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Sample records for portugal ptx profiles

  1. Genes for carbon metabolism and the ToxA virulence factor in Pseudomonas aeruginosa are regulated through molecular interactions of PtxR and PtxS.

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    Abdelali Daddaoua

    Full Text Available Homologs of the transcriptional regulator PtxS are omnipresent in Pseudomonas, whereas PtxR homologues are exclusively found in human pathogenic Pseudomonas species. In all Pseudomonas sp., PtxS with 2-ketogluconate is the regulator of the gluconate degradation pathway and controls expression from its own promoter and also from the P(gad and P(kgu for the catabolic operons. There is evidence that PtxS and PtxR play a central role in the regulation of exotoxin A expression, a relevant primary virulence factor of Pseudomonas aeruginosa. We show using DNaseI-footprint analysis that in P. aeruginosa PtxR binds to the -35 region of the P(toxA promoter in front of the exotoxin A gene, whereas PtxS does not bind to this promoter. Bioinformatic and DNaseI-footprint analysis identified a PtxR binding site in the P(kgu and P(gad promoters that overlaps the -35 region, while the PtxS operator site is located 50 bp downstream from the PtxR site. In vitro, PtxS recognises PtxR with nanomolar affinity, but this interaction does not occur in the presence of 2-ketogluconate, the specific effector of PtxS. DNAaseI footprint assays of P(kgu and P(gad promoters with PtxS and PtxR showed a strong region of hyper-reactivity between both regulator binding sites, indicative of DNA distortion when both proteins are bound; however in the presence of 2-ketogluconate no protection was observed. We conclude that PtxS modulates PtxR activity in response to 2-ketogluconate by complex formation in solution in the case of the P(toxA promoter, or via the formation of a DNA loop as in the regulation of gluconate catabolic genes. Data suggest two different mechanisms of control exerted by the same regulator.

  2. PTX3: A Potential Biomarker in Thyroid Associated Ophthalmopathy

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    Pei Mou

    2018-01-01

    Full Text Available Background. Thyroid associated ophthalmopathy (TAO is an autoimmune disease, which involves inflammation and tissue remodeling. Pentraxin-3 (PTX3 is a component of innate immune system and recently implicated in autoimmunity. This observation may indicate that PTX3 participates in the inflammatory process of TAO. Methods. All studies were performed on TAO patients and healthy controls (45: 28 in total. RNA-seq was used to detect differential gene expression of orbital adipose-connective tissue. Quantitative PCR was performed to verify the results. PTX3 protein in orbital adipose-connective tissues was visualized by immunohistochemistry (IHC. PTX3 concentration in serum was determined by enzyme-linked immunosorbent assay (ELISA. Results. RNA-seq showed 1.86-log⁡2FC higher PTX3 expression in the orbital adipose-connective tissues from TAO group than controls (FDR = 0.0059. qPCR confirmed the difference (5.59-fold increase, p=0.0012. The presence of PTX3 protein was demonstrated. Orbital adipose tissue from healthy controls showed weak staining for PTX3 while tissue from TAO group was strongly positive. Serum PTX3 concentration was significantly elevated in patients when compared to the control group (1.9-fold increase; p<0.0001. Conclusions. Patients with TAO showed increased presence of PTX3 in orbital tissue and serum, which may suggest a potential relationship of PTX3 and TAO.

  3. PTX3: A Potential Biomarker in Thyroid Associated Ophthalmopathy

    Science.gov (United States)

    Chen, Ziyu

    2018-01-01

    Background Thyroid associated ophthalmopathy (TAO) is an autoimmune disease, which involves inflammation and tissue remodeling. Pentraxin-3 (PTX3) is a component of innate immune system and recently implicated in autoimmunity. This observation may indicate that PTX3 participates in the inflammatory process of TAO. Methods All studies were performed on TAO patients and healthy controls (45: 28 in total). RNA-seq was used to detect differential gene expression of orbital adipose-connective tissue. Quantitative PCR was performed to verify the results. PTX3 protein in orbital adipose-connective tissues was visualized by immunohistochemistry (IHC). PTX3 concentration in serum was determined by enzyme-linked immunosorbent assay (ELISA). Results RNA-seq showed 1.86-log⁡2FC higher PTX3 expression in the orbital adipose-connective tissues from TAO group than controls (FDR = 0.0059). qPCR confirmed the difference (5.59-fold increase, p = 0.0012). The presence of PTX3 protein was demonstrated. Orbital adipose tissue from healthy controls showed weak staining for PTX3 while tissue from TAO group was strongly positive. Serum PTX3 concentration was significantly elevated in patients when compared to the control group (1.9-fold increase; p < 0.0001). Conclusions Patients with TAO showed increased presence of PTX3 in orbital tissue and serum, which may suggest a potential relationship of PTX3 and TAO. PMID:29675428

  4. The role of the acute phase protein PTX3 in the ventilator-induced lung injury

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    JM Real

    2008-06-01

    Full Text Available The pentraxin 3 (PTX3 is an acute phase proinflammatory protein produced by fibroblasts and alveolar epithelial cells. We have previously demonstrated that PTX3 is a key modulator of inflammation. Mechanical ventilation (MV is a life saving therapeutic approach for patients with acute lung injury that, nevertheless could lead to an inflammatory response and tissue injury (ventilator-induced lung injury: VILI, representing a major cause of iatrogenic lung damage in intensive units. Our objective was to investigate the role of PTX3 in VILI. PTX3 transgenic, knockout and Wt control mice (n = 12/group were ventilated (45ml·kg–1 until respiratory system Elastance increased 50% (Ers150%, an indicator of VILI. Histological analysis demonstrated that using a Ers150% was appropriate for our analysis since identical degrees of inflammation were observed in Tg, KO and Wt mice as assessed by leukocyte infiltration, oedema, alveolar collapse and number of breaks in alveolar septa. However, Tg mice reached Ers150% faster than Wt controls (p = 0.0225. We also showed that the lack of PTX3 does not abolish the occurrence of VILI in KOs. Gene expression profile of PTX3, IL-1beta, IL-6, KC, IFNgamma, TGFbeta and PCIII were investigated by QPCR. MV drastically up modulated PTX3 as well as IL-1beta, IL-6, IFNgamma and KC. Alternatively, mice were ventilated for 20, 40 and 60 min. The faster kinetics of Tg mice to reach Ers150% was accompanied by an earlier augmentation of IL-1b and PTX3 expression. The kinetics of local PTX3 expression in the lungs of ventilated mice strongly suggests the involvement of this pentraxin in the pathogenesis of VILI.

  5. Geothermal modeling along a two-dimensional crustal profile in Southern Portugal

    Czech Academy of Sciences Publication Activity Database

    Correia, A.; Šafanda, Jan

    2002-01-01

    Roč. 34, č. 1 (2002), s. 47-61 ISSN 0264-3707. [Geothermics at the turn of the century. Evora, 03.04.2000-07.04.2000] Institutional research plan: CEZ:AV0Z3012916 Keywords : geothermal modeling * Southern Portugal * surface heat flow * crustal profile Subject RIV: DC - Siesmology, Volcanology, Earth Structure Impact factor: 1.058, year: 2002

  6. [Profile of tropical diseases in Portugal].

    Science.gov (United States)

    Ventura, F A

    1996-01-01

    The increased incidence of Imported Tropical Diseases in Portugal is correlated to a recent higher standard of living, influence of media and a consequent expansion of tourism, and above all to the close relationship existing between Portugal and Africa. The number and pathology (parasitic diarrhoeas, protozoal and helminthic infections) of in-patients with Tropical Diseases at the Unidade de Doenças Infecciosas, Parasitárias e de Medicina Tropical (UDIP-MT) were described, with special emphasis on Malaria (155 in-patients during the period from 1989 to 1993) and on Sleeping Sickness, where Eflornitin (DFMO) was for the first time used in Portugal. Finally, the impact of HIV epidemic on incidence and different clinical presentations of parasitic and other tropical pathology was also evaluated.

  7. The enhanced activity of mass-selected PtxGd nanoparticles for oxygen electroreduction

    DEFF Research Database (Denmark)

    Velazquez-Palenzuela, Amado Andres; Masini, Federico; Pedersen, Anders Filsøe

    2015-01-01

    Mass-selected platinum–gadolinium alloy nanoparticles (PtxGd NPs) are synthesized for the first time as oxygen reduction reaction (ORR) electrocatalysts using the gas aggregation technique, under ultrahigh vacuum (UHV) conditions. The morphology of the PtxGd catalysts is characterized, and their ......Mass-selected platinum–gadolinium alloy nanoparticles (PtxGd NPs) are synthesized for the first time as oxygen reduction reaction (ORR) electrocatalysts using the gas aggregation technique, under ultrahigh vacuum (UHV) conditions. The morphology of the PtxGd catalysts is characterized...

  8. Implication of the oligomeric state of the N-terminal PTX3 domain in cumulus matrix assembly.

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    Ievoli, Elena; Lindstedt, Ragnar; Inforzato, Antonio; Camaioni, Antonella; Palone, Francesca; Day, Anthony J; Mantovani, Alberto; Salvatori, Giovanni; Salustri, Antonietta

    2011-06-01

    Pentraxin 3 (PTX3) plays a key role in the formation of the hyaluronan-rich matrix of the cumulus oophorus surrounding ovulated eggs that is required for successful fertilization and female fertility. PTX3 is a multimeric protein consisting of eight identical protomers held together by a combination of non-covalent interactions and disulfide bonds. Recent findings suggest that the oligomeric status of PTX3 is important for stabilizing the cumulus matrix. Because the role of PTX3 in the cumulus resides in the unique N-terminal sequence of the protomer, we investigated further this issue by testing the ability of distinct Cys/Ser mutants of recombinant N-terminal region of PTX3 (N(_)PTX3) with different oligomeric arrangement to promote in vitro normal expansion in cumuli from Ptx3-null mice. Here we report that the dimer of the N(_)PTX3 is unable to rescue cumulus matrix organization, and that the tetrameric assembly of the protein is the minimal oligomeric state required for accomplishing this function. We have previously demonstrated that PTX3 binds to HCs of IαI and TSG-6, which are essential for cumulus matrix formation and able to interact with hyaluronan. Interestingly, here we show by solid-phase binding experiments that the dimer of the N(_)PTX3 retains the ability to bind to both IαI and TSG-6, suggesting that the octameric structure of PTX3 provides multiple binding sites for each of these ligands. These findings support the hypothesis that PTX3 contributes to cumulus matrix organization by cross-linking HA polymers through interactions with multiple HCs of IαI and/or TSG-6. The N-terminal PTX3 tetrameric oligomerization was recently reported to be also required for recognition and inhibition of FGF2. Given that this growth factor has been detected in the mammalian preovulatory follicle, we wondered whether FGF2 negatively influences cumulus expansion and PTX3 may also serve in vivo to antagonize its activity. We found that a molar excess of FGF2, above

  9. Antitumor efficacy of a novel CLA-PTX microemulsion against brain tumors: in vitro and in vivo findings.

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    Li, Dan; Yang, Ke; Li, Jie-Si; Ke, Xi-Yu; Duan, Yu; Du, Ruo; Song, Ping; Yu, Ke-Fu; Ren, Wei; Huang, Dan; Li, Xing-Huo; Hu, Xin; Zhang, Xuan; Zhang, Qiang

    2012-01-01

    Considering the observations that linoleic acid conjugated with paclitaxel (CLA-PTX) possesses antitumor activity against brain tumors, is able to cross the blood-brain barrier, but has poor water solubility, the purpose of this study was to prepare a novel CLA-PTX microemulsion and evaluate its activity against brain tumors in vitro and in vivo. The in vitro cytotoxicity of a CLA-PTX microemulsion was investigated in C6 glioma cells. The in vivo antitumor activity of the CLA-PTX microemulsion was evaluated in tumor-bearing nude mice and rats. The pharmacokinetics of the CLA-PTX microemulsion were investigated in rats, and its safety was also evaluated in mice. The average droplet size of the CLA-PTX microemulsion was approximately 176.3 ± 0.8 nm and the polydispersity index was 0.294 ± 0.024. In vitro cytotoxicity results showed that the IC(50) of the CLA-PTX microemulsion was 1.61 ± 0.83 μM for a C6 glioma cell line, which was similar to that of free paclitaxel and CLA-PTX solution (P > 0.05). The antitumor activity of the CLA-PTX microemulsion against brain tumors was confirmed in our in vivo C6 glioma tumor-bearing nude mice as well as in a rat model. In contrast, Taxol(®) had almost no significant antitumor effect in C6 glioma tumor-bearing rats, but could markedly inhibit growth of C6 tumors in C6 glioma tumor-bearing nude mice. The pharmacokinetic results indicated that CLA-PTX in solution has a much longer circulation time and produces higher drug plasma concentrations compared with the CLA-PTX microemulsion. The results of the acute toxicity study showed that the LD(50) of CLA-PTX solution was 103.9 mg/kg. In contrast, the CLA-PTX microemulsion was well tolerated in mice when administered at doses up to 200 mg/kg. CLA-PTX microemulsion is a novel formulation with significant antitumor efficacy in the treatment of brain tumors, and is safer than CLA-PTX solution.

  10. QDP-JIT/PTX: A QDP++ Implementation for CUDA-Enabled GPUs

    Energy Technology Data Exchange (ETDEWEB)

    Winter, Frank T. [JLAB; Edwards, Robert G. [JLAB

    2014-11-01

    These proceedings describe briefly the QDP-JIT/PTX framework for lattice field theory calcula- tions on the CUDA architecture. The framework generates compute kernels in the PTX assembler language which can be compiled to efficient GPU machine code by the NVIDIA JIT compiler. A comprehensive memory management was added to the framework so that applications, e.g. Chroma, can run unaltered on GPU clusters and supercomputers.

  11. [Combination Chemotherapy Including Intraperitoneal(IP)Administration of Paclitaxel(PTX)followed by PTX, CDDP and S-1Triplet Chemotherapy for CY1P0 Gastric Cancer].

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    Shinkai, Masayuki; Imano, Motohiro; Hiraki, Yoko; Kato, Hiroaki; Iwama, Mitsuru; Shiraishi, Osamu; Yasuda, Atsushi; Kimura, Yutaka; Imamoto, Haruhiko; Furukawa, Hiroshi; Yasuda, Takushi

    2017-11-01

    We evaluate the feasibility and efficacy of combination chemotherapy including single intraperitoneal( IP)administration of paclitaxel(PTX), followed by triplet chemotherapy(PTX, cisplatin[CDDP]and S-1: PCS)for CY1P0 gastric cancer. First of all, we performed staging laparoscopy and confirmed CY1P0, and secondary, administrated PTX intraperitoneally. Thirdly, patients received PCS chemotherapy for 2 courses. After antitumor effect had been confirmed, we performed second look laparoscopy. In the case of CY0P0, we performed gastrectomy with D2 lymph nodes dissection. Total 4 patients were enrolled. Grade 3 leukopenia and neutropenia were observed in one patient while intraperitoneal and systemic-chemotherapy. One patients showed PR and 3 patients showed SD. All patients underwent second look laparoscopy. CY0P0 was observed in all patients and gastrectomy with D2 dissection was performed for all patients. Postoperative complications were observed in 2 patients. Two patients were still alive without recurrence, while the remaining 2 had died of liver metastasis and #16 LN metastasis. Combination chemotherapy including single IP PTX followed by PCS systemic-chemotherapy for CY1P0 gastric cancer is feasible and efficient.

  12. An acidic microenvironment sets the humoral pattern recognition molecule PTX3 in a tissue repair mode

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    Doni, Andrea; Musso, Tiziana; Morone, Diego; Bastone, Antonio; Zambelli, Vanessa; Sironi, Marina; Castagnoli, Carlotta; Cambieri, Irene; Stravalaci, Matteo; Pasqualini, Fabio; Laface, Ilaria; Valentino, Sonia; Tartari, Silvia; Ponzetta, Andrea; Maina, Virginia; Barbieri, Silvia S.; Tremoli, Elena; Catapano, Alberico L.; Norata, Giuseppe D.; Bottazzi, Barbara; Garlanda, Cecilia

    2015-01-01

    Pentraxin 3 (PTX3) is a fluid-phase pattern recognition molecule and a key component of the humoral arm of innate immunity. In four different models of tissue damage in mice, PTX3 deficiency was associated with increased fibrin deposition and persistence, and thicker clots, followed by increased collagen deposition, when compared with controls. Ptx3-deficient macrophages showed defective pericellular fibrinolysis in vitro. PTX3-bound fibrinogen/fibrin and plasminogen at acidic pH and increased plasmin-mediated fibrinolysis. The second exon-encoded N-terminal domain of PTX3 recapitulated the activity of the intact molecule. Thus, a prototypic component of humoral innate immunity, PTX3, plays a nonredundant role in the orchestration of tissue repair and remodeling. Tissue acidification resulting from metabolic adaptation during tissue repair sets PTX3 in a tissue remodeling and repair mode, suggesting that matrix and microbial recognition are common, ancestral features of the humoral arm of innate immunity. PMID:25964372

  13. Structural characterization of PTX3 disulfide bond network and its multimeric status in cumulus matrix organization.

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    Inforzato, Antonio; Rivieccio, Vincenzo; Morreale, Antonio P; Bastone, Antonio; Salustri, Antonietta; Scarchilli, Laura; Verdoliva, Antonio; Vincenti, Silvia; Gallo, Grazia; Chiapparino, Caterina; Pacello, Lucrezia; Nucera, Eleonora; Serlupi-Crescenzi, Ottaviano; Day, Anthony J; Bottazzi, Barbara; Mantovani, Alberto; De Santis, Rita; Salvatori, Giovanni

    2008-04-11

    PTX3 is an acute phase glycoprotein that plays key roles in resistance to certain pathogens and in female fertility. PTX3 exerts its functions by interacting with a number of structurally unrelated molecules, a capacity that is likely to rely on its complex multimeric structure stabilized by interchain disulfide bonds. In this study, PAGE analyses performed under both native and denaturing conditions indicated that human recombinant PTX3 is mainly composed of covalently linked octamers. The network of disulfide bonds supporting this octameric assembly was resolved by mass spectrometry and Cys to Ser site-directed mutagenesis. Here we report that cysteine residues at positions 47, 49, and 103 in the N-terminal domain form three symmetric interchain disulfide bonds stabilizing four protein subunits in a tetrameric arrangement. Additional interchain disulfide bonds formed by the C-terminal domain cysteines Cys(317) and Cys(318) are responsible for linking the PTX3 tetramers into octamers. We also identified three intrachain disulfide bonds within the C-terminal domain that we used as structural constraints to build a new three-dimensional model for this domain. Previously it has been shown that PTX3 is a key component of the cumulus oophorus extracellular matrix, which forms around the oocyte prior to ovulation, because cumuli from PTX3(-/-) mice show defective matrix organization. Recombinant PTX3 is able to restore the normal phenotype ex vivo in cumuli from PTX3(-/-) mice. Here we demonstrate that PTX3 Cys to Ser mutants, mainly assembled into tetramers, exhibited wild type rescue activity, whereas a mutant, predominantly composed of dimers, had impaired functionality. These findings indicate that protein oligomerization is essential for PTX3 activity within the cumulus matrix and implicate PTX3 tetramers as the functional molecular units required for cumulus matrix organization and stabilization.

  14. PTX3, a Humoral Pattern Recognition Molecule, in Innate Immunity, Tissue Repair, and Cancer.

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    Garlanda, Cecilia; Bottazzi, Barbara; Magrini, Elena; Inforzato, Antonio; Mantovani, Alberto

    2018-04-01

    Innate immunity includes a cellular and a humoral arm. PTX3 is a fluid-phase pattern recognition molecule conserved in evolution which acts as a key component of humoral innate immunity in infections of fungal, bacterial, and viral origin. PTX3 binds conserved microbial structures and self-components under conditions of inflammation and activates effector functions (complement, phagocytosis). Moreover, it has a complex regulatory role in inflammation, such as ischemia/reperfusion injury and cancer-related inflammation, as well as in extracellular matrix organization and remodeling, with profound implications in physiology and pathology. Finally, PTX3 acts as an extrinsic oncosuppressor gene by taming tumor-promoting inflammation in murine and selected human tumors. Thus evidence suggests that PTX3 is a key homeostatic component at the crossroad of innate immunity, inflammation, tissue repair, and cancer. Dissecting the complexity of PTX3 pathophysiology and human genetics paves the way to diagnostic and therapeutic exploitation.

  15. PTX3 predicts severe disease in febrile patients at the emergency department

    NARCIS (Netherlands)

    de Kruif, Martijn D.; Limper, Maarten; Sierhuis, Karlien; Wagenaar, Jiri F. P.; Spek, C. Arnold; Garlanda, Cecilia; Cotena, Alessia; Mantovani, Alberto; ten Cate, Hugo; Reitsma, Pieter H.; van Gorp, Eric C. M.

    2010-01-01

    Objectives: The long pentraxin PTX3 is a promising marker of disease severity in severely ill patients. In order to identify patients warranting critical care as quickly as possible, we investigated the value of PTX3 as a biomarker for disease severity in patients presenting with fever at the

  16. Interactions of the humoral pattern recognition molecule PTX3 with the complement system

    DEFF Research Database (Denmark)

    Doni, Andrea; Garlanda, Cecilia; Bottazzi, Barbara

    2012-01-01

    The innate immune system comprises a cellular and a humoral arm. The long pentraxin PTX3 is a fluid phase pattern recognition molecule, which acts as an essential component of the humoral arm of innate immunity. PTX3 has antibody-like properties including interactions with complement components....... PTX3 interacts with C1q, ficolin-1 and ficolin-2 as well as mannose-binding lectin, recognition molecules in the classical and lectin complement pathways. The formation of these heterocomplexes results in cooperative pathogen recognition and complement activation. Interactions with C4b binding protein...

  17. The Intra Industry Trade between Portugal European Union, Portugal Spain, Portugal-France, Portugal Germany, Portugal-Ireland, Portugal-Greece and Portugal-Netherlands - a Dynamic Panel Data Analysis (1996 2000)

    OpenAIRE

    Horácio Faustino; Nuno Carlos Leitão

    2005-01-01

    PortugalÂ’s main trade partners have been Spain, Germany and France. In this paper we analyse the intra industry trade in the manufacturing industry between Portugal Spain, Portugal-France, Portugal Germany, Portugal-Ireland and Portugal-Greece. We also present the results of intra industry trade (IIT) between Portugal and the European Union. The innovation, technological progress, human capital, and scale economies are some of the explicative variables of the intra industry trade phenomena. ...

  18. Human pentraxin 3 (PTX3 as a novel biomarker for the diagnosis of pulmonary arterial hypertension.

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    Yuichi Tamura

    Full Text Available BACKGROUND: Although inflammation is an important feature of pulmonary arterial hypertension (PAH, the usefulness of local inflammatory markers as biomarkers for PAH is unknown. In this study, we tested whether plasma concentrations of human pentraxin 3 (PTX3, a local inflammatory marker, would be a useful biomarker for detecting PAH. METHODS: Plasma PTX3 concentrations were evaluated in 50 PAH patients (27 with idiopathic PAH, 17 with PAH associated with connective tissue disease (CTD-PAH, and six with congenital heart disease, 100 age and sex-matched healthy controls, and 34 disease-matched CTD patients without PAH. Plasma concentrations of B-type natriuretic peptide (BNP and C-reactive protein (CRP were also determined. RESULTS: Mean PTX3 levels were significantly higher in all PAH patients than in the healthy controls (4.40±0.37 vs. 1.94±0.09 ng/mL, respectively; P<0.001. Using a threshold level of 2.84 ng/mL, PTX3 yielded a sensitivity of 74.0% and a specificity of 84.0% for the detection of PAH. In CTD-PAH patients, mean PTX3 concentrations were significantly higher than in CTD patients without PAH (5.02±0.69 vs. 2.40±0.14 ng/mL, respectively; P<0.001. There was no significant correlation between plasma levels of PTX3 and BNP or CRP. Receiver operating characteristic (ROC curves for screening PAH in patients with CTD revealed that PTX3 (area under the ROC curve 0.866 is superior to BNP. Using a PTX3 threshold of 2.85 ng/mL maximized true-positive and false-negative results (sensitivity 94.1%, specificity 73.5%. CONCLUSION: Plasma concentrations of PTX3 may be a better biomarker of PAH than BNP, especially in patients with CTD.

  19. Medicinal Product Regulation: Portugal׳s Framework.

    Science.gov (United States)

    Herdeiro, Maria Teresa; Bastos, Paulo D; Teixeira-Rodrigues, António; Roque, Fátima

    2016-09-01

    The pharmaceutical industry is one of the most tightly regulated sectors, and it is essential to know each country׳s legal framework to understand the regulation, approval, and marketing of medicinal products for human use. This article describes the main statutes and procedures governing medicinal products for human use in Portugal and the role of the country׳s National Medicines and Health Products Authority (Autoridade Nacional do Medicamento e Produtos de Saúde, I.P.; INFARMED). From the most recently available data, an update of requests and approvals concerning marketing authorizations, variations, pricing, and reimbursements is provided. Data were sourced from the INFARMED website, Infomed (database of medicinal products for human use), and periodic reports issued by national authorities. Organic laws, acts, and law decrees published in the government gazette (Diário da República) are cited and reproduced as required. In 2015 Portugal ranked fifth in the European System of Medicines Evaluation in terms of the number of completed procedures as a reference member state. Approximately 80% of all approved drug applications in Portugal in 2015 were for generic drugs, mostly pertaining to the nervous system. In Portugal, INFARMED monitors drug quality, safety profile, and efficacy in all stages of the drug life cycle, ensuring patients' safety. The Portuguese market for medicinal products for human use has been appreciably changed by the advent of generic drugs. There is an increased trend for new request applications for biological and biotechnological substances. Copyright © 2016 Elsevier HS Journals, Inc. All rights reserved.

  20. Antitumor effect of iRGD-modified liposomes containing conjugated linoleic acid–paclitaxel (CLA-PTX on B16-F10 melanoma

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    Du R

    2014-06-01

    Full Text Available Ruo Du,1 Ting Zhong,1 Wei-Qiang Zhang,1 Ping Song,1 Wen-Ding Song,1 Yang Zhao,1 Chao-Wang,1 Yi-Qun Tang,3 Xuan Zhang,1,2 Qiang Zhang1,2 1Department of Pharmaceutics, 2State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 3Department of Clinical Pharmacy, China Pharmaceutical University, Nanjing, People’s Republic of China Abstract: In the present study, we prepared a novel delivery system of iRGD (CRGDK/RGPD/EC-modified sterically stabilized liposomes (SSLs containing conjugated linoleic acid–paclitaxel (CLA-PTX. The anti-tumor effect of iRGD-SSL-CLA-PTX was investigated on B16-F10 melanoma in vitro and in vivo. The in vitro targeting effect of iRGD-modified SSLs was investigated in a real-time confocal microscopic analysis experiment. An endocytosis-inhibition assay was used to evaluate the endocytosis pathways of the iRGD-modified SSLs. In addition, the in vitro cellular uptake and in vitro cytotoxicity of iRGD-SSL-CLA-PTX were evaluated in B16-F10 melanoma cells. In vivo biodistribution and in vivo antitumor effects of iRGD-SSL-CLA-PTX were investigated in B16-F10 tumor-bearing mice. The induction of apoptosis by iRGD-SSL-CLA-PTX was evaluated in tumor-tissue sections. Real-time confocal microscopic analysis results indicated that the iRGD-modified SSLs internalized into B16-F10 cells faster than SSLs. The identified endocytosis pathway of iRGD-modified SSLs indicated that energy- and lipid raft-mediated endocytosis played a key role in the liposomes’ cellular uptake. The results of the cellular uptake experiment indicated that the increased cellular uptake of CLA-PTX in the iRGD-SSL-CLA-PTX-treated group was 1.9-, 2.4-, or 2.1-fold compared with that in the CLA-PTX group after a 2-, 4-, or 6-hour incubation, respectively. In the biodistribution test, the CLA-PTX level in tumor tissues from iRGD-SSL-CLA-PTX-treated mice at 1 hour (1.84±0.17 µg/g and 4 hours (1.17±0

  1. Human Albumin Fragments Nanoparticles as PTX Carrier for Improved Anti-cancer Efficacy

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    Liang Ge

    2018-06-01

    Full Text Available For enhanced anti-cancer performance, human serum albumin fragments (HSAFs nanoparticles (NPs were developed as paclitaxel (PTX carrier in this paper. Human albumins were broken into fragments via degradation and crosslinked by genipin to form HSAF NPs for better biocompatibility, improved PTX drug loading and sustained drug release. Compared with crosslinked human serum albumin NPs, the HSAF-NPs showed relative smaller particle size, higher drug loading, and improved sustained release. Cellular and animal results both indicated that the PTX encapsulated HSAF-NPs have shown good anti-cancer performance. And the anticancer results confirmed that NPs with fast cellular internalization showed better tumor inhibition. These findings will not only provide a safe and robust drug delivery NP platform for cancer therapy, but also offer fundamental information for the optimal design of albumin based NPs.

  2. Assessment of ptxD gene as an alternative selectable marker for Agrobacterium-mediated maize transformation.

    Science.gov (United States)

    Nahampun, Hartinio N; López-Arredondo, Damar; Xu, Xing; Herrera-Estrella, Luis; Wang, Kan

    2016-05-01

    Bacterial phosphite oxidoreductase gene and chemical phosphite can be used as a selection system for Agrobacterium -mediated maize transformation. Application of phosphite (Phi) on plants can interfere the plant metabolic system leading to stunted growth and lethality. On the other hand, ectopic expression of the ptxD gene in tobacco and Arabidopsis allowed plants to grow in media with Phi as the sole phosphorous source. The phosphite oxidoreductase (PTXD) enzyme catalyzes the conversion of Phi into phosphate (Pi) that can then be metabolized by plants and utilized as their essential phosphorous source. Here we assess an alternative selectable marker based on a bacterial ptxD gene for Agrobacterium-mediated maize transformation. We compared the transformation frequencies of maize using either the ptxD/Phi selection system or a standard herbicide bar/bialaphos selection system. Two maize genotypes, a transformation amenable hybrid Hi II and an inbred B104, were tested. Transgene presence, insertion copy numbers, and ptxD transcript levels were analyzed and compared. This work demonstrates that the ptxD/Phi selection system can be used for Agrobacterium-mediated maize transformation of both type I and type II callus culture and achieve a comparable frequency as that of the herbicide bar/bialaphos selection system.

  3. Portugal.

    Science.gov (United States)

    Eckles, David; Toro, Leonor, Ed.

    Brief information is provided on the region, climate, agriculture and industry of 10 provinces in Portugal: Tras-os-Montes e Alto Douro, located in Portugal's northeastern region; Beira Alta, the province with Portugal's highest elevation point; Beira Baixa, one of Portugal's poorest regions; Beira Litoral, located in central Portugal along the…

  4. Heterocomplexes of mannose-binding lectin and the pentraxins PTX3 or SAP trigger cross-activation of the complement system

    DEFF Research Database (Denmark)

    Ma, Ying Jie; Doni, Andrea; Skjødt, Mikkel-Ole

    2011-01-01

    The long pentraxin 3 (PTX3), serum amyloid P component (SAP) and C-reactive protein (CRP) belong to the pentraxin family of pattern recognition molecules involved in tissue homeostasis and innate immunity. They interact with C1q from the classical complement pathway. Whether this also occurs via...... the analogous mannose-binding lectin (MBL) from the lectin complement pathway is unknown. Thus, we investigated the possible interaction between MBL and the pentraxins. We report that MBL bound PTX3 and SAP partly via its collagen-like domain, but not CRP. MBL:PTX3 complex formation resulted in recruitment of C......1q, but this was not seen for the MBL:SAP complex. However, both MBL:PTX3 and MBL:SAP complexes enhanced C4 and C3 deposition and opsonophagocytosis of Candida albicans by polymorphonuclear leukocytes. Interaction between MBL and PTX3 lead to communication between the lectin and classical complement...

  5. In situ X-ray data collection from highly sensitive crystals of Pseudomonas putida PtxS in complex with DNA

    International Nuclear Information System (INIS)

    Pineda-Molina, E.; Daddaoua, A.; Krell, T.; Ramos, J. L.; García-Ruiz, J. M.; Gavira, J. A.

    2012-01-01

    The crystallization of both native P. putida transcriptional regulator PtxS and its complex with its DNA recognition sequence using the counter-diffusion method are reported. Pseudomonas putida PtxS is a member of the LacI protein family of transcriptional regulators involved in glucose metabolism. All genes involved in this pathway are clustered into two operons, kgu and gad. PtxS controls the expression of the kgu and gad operons as well as its own transcription. The PtxS operator is a perfect palindrome, 5′-TGAAACCGGTTTCA-3′, which is present in all three promoters. Crystallization of native PtxS failed, and PtxS–DNA crystals were finally produced by the counter-diffusion technique. A portion of the capillary used for crystal growth was attached to the end of a SPINE standard cap and directly flash-cooled in liquid nitrogen for diffraction tests. A full data set was collected with a beam size of 10 × 10 µm. The crystal belonged to the trigonal space group P3, with unit-cell parameters a = b = 213.71, c = 71.57 Å. Only unhandled crystals grown in capillaries of 0.1 mm inner diameter diffracted X-rays to 1.92 Å resolution

  6. [Characterization of lipid profile in primary health care users in Portugal].

    Science.gov (United States)

    Cortez-Dias, Nuno; Robalo Martins, Susana; Belo, Adriana; Fiúza, Manuela

    2013-12-01

    To characterize the distribution of total cholesterol (TC), LDL cholesterol (LDL-C), HDL cholesterol (HDL-C) and triglycerides in primary health care users. We performed a cross-sectional study in a primary care setting, involving 719 general practitioners based on stratified distribution proportional to the population density of each region of Portugal. The first two adult patients scheduled for an appointment on a given day were invited to participate. A questionnaire was applied to assess sociodemographic, clinical and laboratory data including lipid profile. The study included 16 856 individuals (mean age 58.1±15.1 years; 61.6% women). Data on TC, LDL-C, HDL-C and triglycerides were available for 95.9% (n=16 159), 59.1% (n=9956), 95.4% (n=16 074) and 97.9% (n=16 494) of the population, respectively. Hypercholesterolemia (TC ≥200 mg/dl) was detected in 47%, and 38.4% had high levels of LDL-C (≥130 mg/dl). Hypertriglyceridemia (≥200 mg/dl) and low HDL-C (<40 mg/dl) were less prevalent, affecting roughly 13% of the population. Dyslipidemia was more common in middle-aged men and in post-menopausal women. Of the population aged over 40, 54.1% met eligibility criteria for lipid-lowering therapy and 44.7% were medicated with statins, but only 16.0% of these had TC ≤175 mg/dl. Dyslipidemia is highly prevalent in primary health care users in Portugal. It is particularly common in middle-aged men and post-menopausal women, who should be considered target groups for preventive public health measures. Copyright © 2013 Sociedade Portuguesa de Cardiologia. Published by Elsevier España. All rights reserved.

  7. The sweet side of a long pentraxin: how glycosylation affects PTX3 functions in innate immunity and inflammation

    Directory of Open Access Journals (Sweden)

    Antonio eInforzato

    2013-01-01

    Full Text Available Innate immunity represents the first line of defence against pathogens and plays key roles in activation and orientation of the adaptive immune response. The innate immune system comprises both a cellular and a humoral arm. Components of the humoral arm include soluble pattern recognition molecules (PRMs that recognise pathogen associated molecular patterns (PAMPs and initiate the immune response in coordination with the cellular arm, therefore acting as functional ancestors of antibodies. The long pentraxin PTX3 is a prototypic soluble PRM that is produced at sites of infection and inflammation by both somatic and immune cells. Gene targeting of this evolutionarily conserved protein has revealed a non-redundant role in resistance to selected pathogens. Moreover, PTX3 exerts important functions at the crossroad between innate immunity, inflammation and female fertility. The human PTX3 protein contains a single N-glycosylation site that is fully occupied by complex type oligosaccharides, mainly fucosylated and sialylated biantennary glycans. Glycosylation has been implicated in a number of PTX3 activities, including neutralization of influenza viruses, modulation of the complement system, and attenuation of leukocyte recruitment. Therefore, this post translational modification might act as a fine tuner of PTX3 functions in native immunity and inflammation.Here we review the studies on PTX3, with emphasis on the glycan-dependent mechanisms underlying pathogen recognition and crosstalk with other components of the innate immune system.

  8. Ficolin-1-PTX3 complex formation promotes clearance of altered self-cells and modulates IL-8 production

    DEFF Research Database (Denmark)

    Ma, Ying Jie; Doni, Andrea; Romani, Luigina

    2013-01-01

    for enhancement of phagocytosis by human monocyte-derived macrophages and downregulation of IL-8 production during phagocytosis. On A. fumigatus, PTX3 exposed the C-terminal portion of the molecule, probably resulting in steric hindrance of ficolin-1 interaction with PTX3. These results demonstrate that ficolin-1...

  9. Country policy profile - Portugal. August 2015

    International Nuclear Information System (INIS)

    2015-08-01

    In Portugal, electricity from renewable sources is mainly promoted through a feed-in tariff (FiT). The support regime for electricity generated from renewable energy sources (except large hydropower plants) is still in place for existing installations and for micro and mini generation units. Support to new installations can be provided through specific power granting tenders. There is currently no direct support mechanism for RES-H. In the transport sector, the main incentives are a bio-fuel quota system and a tax exemption to small producers (PPDs). The Portuguese progress report was released by the EC in June 2014

  10. PTX3 is up-regulated in epithelial mammary cells during S. aureus intramammary infection in goat

    Directory of Open Access Journals (Sweden)

    Joel Fernando Soares Filipe

    2015-07-01

    PTX3 was up-regulated in epithelial mammary cells and in milk cells after S. aureus infection, demonstrating that it represents a first line of immune defense in goat udder. No modulation was observed in macrophages, in the secretum and in the ductal epithelial cells. Further experiments are needed to elucidate the role of PTX3 in the pathogenesis of S. aureus infection.

  11. Country policy profile - Portugal. October 2014

    International Nuclear Information System (INIS)

    2014-10-01

    In Portugal, electricity from renewable sources is mainly promoted through a feed-in tariff (FiT). The support regime for electricity generated from renewable energy sources (except large hydropower plants) is still in place for existing installations and for micro and mini generation units. Support to new installations can be provided through specific power granting tenders. There is currently no direct support mechanism for RES-H. In the transport sector, the main incentives are a bio-fuel quota system and a tax exemption to small producers (PPDs). The Portuguese progress report was released by the EC in June 2014 and no further policy changes have been documented since then

  12. Tectonic and lithological controls on fluvial landscape development in central-eastern Portugal: Insights from long profile tributary stream analyses

    Science.gov (United States)

    Martins, António A.; Cabral, João; Cunha, Pedro P.; Stokes, Martin; Borges, José; Caldeira, Bento; Martins, A. Cardoso

    2017-01-01

    This study examines the long profiles of tributaries of the Tagus and Zêzere rivers in Portugal (West Iberia) in order to provide new insights into patterns, timing, and controls on drainage development during the Quaternary incision stage. The studied streams are incised into a relict culminant fluvial surface, abandoned at the beginning of the incision stage. The streams flow through a landscape with bedrock variations in lithology (mainly granites and metasediments) and faulted blocks with distinct uplift rates. The long profiles of the analyzed streams record an older transitory knickpoint/knickzone separating (1) an upstream relict graded profile, with lower steepness and higher concavity, that reflects a long period of quasi-equilibrium conditions reached after the beginning of the incision stage, and (2) a downstream rejuvenated long profile, with steeper gradient and lower concavity, particularly for the final reach, which is often convex. The rejuvenated reaches testify to the upstream propagation of several incision waves, interpreted as the response of each stream to increasing crustal uplift and prolonged periods of base-level lowering by the trunk drainages, coeval with low sea level conditions. The morphological configurations of the long profiles enabled spatial and relative temporal patterns of incisions to be quantified. The incision values of streams flowing on the Portuguese Central Range (PCR; ca. 380-150 m) are variable but generally higher than the incision values of streams flowing on the adjacent South Portugal Planation Surface (SPPS; ca. 220-110 m), corroborating differential uplift of the PCR relative to the SPPS. Owing to the fact that the relict graded profiles can be correlated with the Tagus River T1 terrace (1.1-0.9 My) present in the study area, incision rates can be estimated (1) for the streams located in the PCR, 0.38-0.15 m/ky and (2) for the streams flowing on the SPPS, 0.22-0.12 m/ky. The differential uplift inferred in the

  13. Permanent electric dipole moments of PtX (X = H, F, Cl, Br, and I) by the composite approach

    Science.gov (United States)

    Deng, Dan; Lian, Yongqin; Zou, Wenli

    2017-11-01

    Using the FPD composite approach of Peterson et. al. we calculate the permanent electric dipole moments of PtX (X = H, F, Cl, Br, and I) at the equilibrium geometries of their ground states. The dipole moment of PtF is estimated to be 3.421 Debye, being very close to the experimental value of 3.42(6) Debye. This research also suggests the ordering of dipole moments of PtX being proportional to the electronegativity of X.

  14. Exploring the phase space of time of flight mass selected PtxY nanoparticles

    DEFF Research Database (Denmark)

    Masini, Federico; Hernandez-Fernandez, Patricia; Deiana, Davide

    2014-01-01

    the importance of transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS) and ion scattering spectroscopy (ISS) for verifying the morphology, size distribution and chemical composition of the nanoparticles. Furthermore, we correlate the morphology and the composition of the Ptx...

  15. Targeting property and toxicity of a novel ultrasound contrast agent microbubble carrying the targeting and drug-loaded complex FA-CNTs-PTX on MCF7 cells.

    Science.gov (United States)

    Zhang, Jie; Zhang, Yu; Liu, Junxi; Li, Guozhong; Wen, Zhaohui; Zhao, Yue; Zhang, Xiangyu; Liu, Fenghua

    2017-10-01

    The application of ultrasound contrast agents not only is confined to the enhancement of ultrasound imaging but also has started to be used as a drug system for diagnosis and treatment. In this paper, Span60 and PEG1500 were used as membrane materials, and a new targeting and drug-loading multifunctional ultrasound contrast agent microbubble enveloping the FA-CNTs-PTX complex was successfully prepared by acoustic cavitation. With the breast cancer cell line MCF7 as the research target, the effects of the microbubble with FA-CNTs-PTX on the proliferation and toxicity of MCF7 cells were studied using a CCK-8 and AO/EB double-staining method. The influences of the microbubbles with FA-CNTs-PTX on the cellular morphology and apoptosis period of the MCF7 cells were detected using an inverted fluorescence microscope. The apoptosis of MCF7 cells induced by the microbubbles with FA-CNTs-PTX was investigated with flow cytometry and an annexin and PI double staining fluorescence quantitative analysis. The results indicated that the ultrasound contrast agent microbubble with FA-CNTs-PTX remarkably inhibited the proliferation of MCF7 cells, which was mainly controlled by the drug loading rate and the nanometer size of the microbubbles. Moreover, the proliferative inhibition rate of the microbubbles with FA-CNTs-PTX was related to the cell apoptosis period of MCF7 cells. Its inhibition degree on the proliferation of MCF7 cells was higher than that of the hepatoma HepG2 cells. The apoptosis rate of MCF7 cells induced by the microbubbles with FA-CNTs-PTX was higher than that of normal human umbilical vein endothelial cells (HUVECs), and the microbubbles with FA-CNTs-PTX could target the MCF7 cells. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. Portugal: Lisbon seeks to juggle power sell-off, oil deregulation and advent of gas

    International Nuclear Information System (INIS)

    Maxwell, K.

    1994-01-01

    A profile of Portugal's energy sector is presented and the energy balance (1993) in terms of oil, gas, coal, electricity and other sources is located. Topics discussed include the import of natural gas supplies from Algeria by 1996; the construction of a 400km natural gas pipeline; the breakup of the Electricidada de Portugal into separate units, and the impact of liberation and privatisation on the power sector. The first large-scale private power generation, and deregulation and competition in Portugal's oil industry are also examined in this article. (UK)

  17. ptxD gene in combination with phosphite serves as a highly effective selection system to generate transgenic cotton (Gossypium hirsutum L.).

    Science.gov (United States)

    Pandeya, Devendra; Campbell, LeAnne M; Nunes, Eugenia; Lopez-Arredondo, Damar L; Janga, Madhusudhana R; Herrera-Estrella, Luis; Rathore, Keerti S

    2017-12-01

    This report demonstrates the usefulness of ptxD/phosphite as a selection system that not only provides a highly efficient and simple means to generate transgenic cotton plants, but also helps address many of the concerns related to the use of antibiotic and herbicide resistance genes in the production of transgenic crops. Two of the most popular dominant selectable marker systems for plant transformation are based on either antibiotic or herbicide resistance genes. Due to concerns regarding their safety and in order to stack multiple traits in a single plant, there is a need for alternative selectable marker genes. The ptxD gene, derived from Pseudomonas stutzeri WM88, that confers to cells the ability to convert phosphite (Phi) into orthophosphate (Pi) offers an alternative selectable marker gene as demonstrated for tobacco and maize. Here, we show that the ptxD gene in combination with a protocol based on selection medium containing Phi, as the sole source of phosphorus (P), can serve as an effective and efficient system to select for transformed cells and generate transgenic cotton plants. Fluorescence microscopy examination of the cultures under selection and molecular analyses on the regenerated plants demonstrate the efficacy of the system in recovering cotton transformants following Agrobacterium-mediated transformation. Under the ptxD/Phi selection, an average of 3.43 transgenic events per 100 infected explants were recovered as opposed to only 0.41% recovery when bar/phosphinothricin (PPT) selection was used. The event recovery rates for nptII/kanamycin and hpt/hygromycin systems were 2.88 and 2.47%, respectively. Molecular analysis on regenerated events showed a selection efficiency of ~ 97% under the ptxD/Phi system. Thus, ptxD/Phi has proven to be a very efficient, positive selection system for the generation of transgenic cotton plants with equal or higher transformation efficiencies compared to the commonly used, negative selection systems.

  18. Long-Term Effectiveness of the Zilver PTX Drug-Eluting Stent for Femoropopliteal Peripheral Artery Disease in Patients with No Patent Tibial Runoff Vessels-Results from the Zilver PTX Japan Post-Market Surveillance Study.

    Science.gov (United States)

    Cipollari, Stefano; Yokoi, Hiroyoshi; Ohki, Takao; Kichikawa, Kimihiko; Nakamura, Masato; Komori, Kimihiro; Nanto, Shinsuke; O'Leary, Erin E; Lottes, Aaron E; Saunders, Alan T; Dake, Michael D

    2018-01-01

    To evaluate 2-year results of the Zilver PTX (Cook Medical, Bloomington, Indiana) drug-eluting stent (DES) for femoropopliteal peripheral artery disease (PAD) in patients with no continuous patent infrapopliteal runoff arteries compared with patients with ≥ 1 continuous patent runoff vessels. A retrospective analysis of patients with femoropopliteal PAD enrolled in the Zilver PTX Post-Market Surveillance Study in Japan was performed. There were no exclusion criteria. Outcomes, including freedom from target lesion revascularization (TLR), patency, and clinical benefit, for the no-runoff group (n = 54) were compared with the runoff group (n = 846). The 2 groups were similar in terms of demographics, lesion characteristics, and comorbidities (P > .05). There was a higher incidence of critical limb ischemia in the no-runoff group compared with the runoff group (44.8% vs 19.7%; P < .01). There were 3 amputations (5.6%) in the no-runoff group versus 7 amputations (0.8%) in the runoff group (P = .02). At 2 years, freedom from TLR rates were 81.3% versus 83.8% (P = .87), patency rates were 68.4% versus 70.7% (P = .95), and clinical benefit rates were 73.7% versus 80.0% (P = .16) in the no-runoff versus runoff group, respectively. Results in patients with no continuous patent tibial runoff were favorable through 2 years and similar to results for patients with ≥ 1 continuous patent runoff vessels, indicating that the Zilver PTX DES may be a valid treatment option for patients with these difficult-to-treat lesions. Copyright © 2017 SIR. Published by Elsevier Inc. All rights reserved.

  19. [A case of breast cancer with multiple hepatic metastasis successfully treated with S-1/PTX and S-1 chemotherapy].

    Science.gov (United States)

    Hashimoto, Masakazu; Moriyuki, Toshio; Kuranishi, Fumito; Niitsu, Hiroaki; Fujikuni, Nobuaki; Iwako, Hiroshi; Kuroda, Yoshinori

    2010-06-01

    The case is a woman in her 50's. A total glandectomy was performed for her breast cancer on August 8, 1998, and subsequently chemotherapy(5'-DFUR, CMF, uracil.tegafur, CEF, and docetaxel)as well as radiation therapy and surgical resection have been performed for local recurrence. With multiple hepatic metastasis recognized in September, 2007, chemotherapy combined with S-1/paclitaxel(PTX)has been performed. In view of the side effects such as reduction in appetite and leukocyte, the dosage has been reduced as of the second course of treatment. With the disappearance of hepatic metastasis on CT, 6 courses of S-1monotherapy have been performed after completing 6 courses of chemotherapy combined with S-1/ PTX. As of March, 2009, the therapeutic effect shows that continuous CR and outpatient follow-up have been performed while maintaining QOL. Since any chemotherapy after thirdline treatment for recurrent breast cancer has not been established yet, chemotherapy combined with S-1/PTX is considered to be one of the regimens and therefore, the second and thirdphase clinical tests ahead are expected to bring better outcomes.

  20. Portugal; Portugal

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    This short report summarizes the main lines of the energy policy of Portugal. It presents the main energy companies and utilities (EDP, CPPE, REN, Petrogal, GDP, Galp SGPS) of the country, the energy supplies (resources, electricity, petroleum, coal, natural gas), the prices and pricing policy, the global energy consumption per sector, the stakes and perspectives of the energy market (forecasts, contracts). (J.S.)

  1. Tendências comportamentais frente à saúde de imigrantes brasileiros em Portugal Behavioral health trends of Brazilian immigrants in Portugal

    Directory of Open Access Journals (Sweden)

    Maria da Penha de Lima Coutinho

    2010-12-01

    Full Text Available Este estudo teve como objetivo principal obter um conhecimento das condições e configurações das formações de imigrantes brasileiros no contexto português. De modo mais específico, procurou-se determinar quais fatores influenciam a busca, pelos imigrantes, dos serviços de saúde existentes no país acolhedor. A amostra foi composta por 75 brasileiros que vivem em Portugal, sendo 35 homens e 40 mulheres. Os dados foram coletados através de um questionário sociodemográfico e analisados por meio de estatísticas descritivas e inferenciais. Os resultados mostraram um perfil atualmente crescente do imigrante brasileiro em Portugal e a sua inserção em um grupo de risco social, refletido nas suas precárias condições psicológicas, sociais e, mais especificamente, no campo da saúde.This study aimed to understand the main conditions and setting of the Brazilian immigrants formations in the Portuguese context. Specifically, the aim was to clarify which factors contribute to determine the searching for Health services in the host country. The sample was consisted by 75 Brazilians who live in Portugal, from which 35 were men and 40 were women. The data were collected by a socio-demographic questionnaire and analyzed by descriptive and inferential statistics. The results showed an increasing of a Brazilian Immigrants' profile in Portugal, and the insertion of such into a group of social risk, reflected in their psychological and social conditions, and more specifically in the Health field.

  2. Toxin profiles of five geographical isolates of Dinophysis spp. from North and South America.

    Science.gov (United States)

    Fux, Elie; Smith, Juliette L; Tong, Mengmeng; Guzmán, Leonardo; Anderson, Donald M

    2011-02-01

    Marine dinoflagellates of the genus Dinophysis can produce toxins of the okadaic acid (OA) and pectenotoxin (PTX) groups. These lipophilic toxins accumulate in filter-feeding shellfish and cause an illness in consumers called diarrhetic shellfish poisoning (DSP). In 2008, a bloom of Dinophysis led to the closure of shellfish harvesting areas along the Texas coast, one of the first DSP-related closures in the U.S. This event resulted in a broad study of toxin production in isolates of Dinophysis spp. from U.S. waters. In the present study, we compared toxin profiles in geographical isolates of Dinophysis collected in the U.S. (Eel Pond, Woods Hole MA; Martha's Vineyard, MA; and Port Aransas Bay, Texas), and in those from Canada (Blacks Harbour, Bay of Fundy) and Chile (Reloncavi Estuary), when cultured in the laboratory under the same conditions. For each isolate, the mitochondrial cox1 gene was sequenced to assist in species identification. Strains from the northeastern U.S. and Canada were all assigned to Dinophysis acuminata, while those from Chile and Texas were most likely within the D. acuminata complex whereas precise species designation could not be made with this marker. Toxins were detected in all Dinophysis isolates and each isolate had a different profile. Toxin profiles of isolates from Eel Pond, Martha's Vineyard, and Bay of Fundy were most similar, in that they all contained OA, DTX1, and PTX2. The Eel Pond isolate also contained OA-D8 and DTX1-D7, and low levels (unconfirmed structurally) of DTX1-D8 and DTX1-D9. D. acuminata from Martha's Vineyard produced DTX1-D7, along with OA, DTX1, and PTX2, as identified in both the cells and the culture medium. D. acuminata from the Bay of Fundy produced DTX1 and PTX2, as found in both cells and culture medium, while only trace amounts of OA were detected in the medium. The Dinophysis strain from Texas only produced OA, and the one from Chile only PTX2, as confirmed in both cells and culture medium. Published

  3. Novel approach for a PTX/VEGF dual drug delivery system in cardiovascular applications-an innovative bulk and surface drug immobilization.

    Science.gov (United States)

    Wulf, Katharina; Teske, Michael; Matschegewski, Claudia; Arbeiter, Daniela; Bajer, Dalibor; Eickner, Thomas; Schmitz, Klaus-Peter; Grabow, Niels

    2018-06-01

    The successive incorporation of several drugs into the polymeric bulk of implants mostly results in loss of considerable quantity of one drug, and/or the loss in quality of the coating and also in changes of drug release time points. A dual drug delivery system (DDDS) based on poly-L-lactide (PLLA) copolymers combining the effective inhibition of smooth muscle cell proliferation while simultaneously promoting re-endothelialization was successfully developed. To overcome possible antagonistic drug interactions and the limitation of the polymeric bulk material as release system for dual drugs, a novel concept which combines the bulk and surface drug immobilization for a DDDS was investigated. The advantage of this DDDS is that the bulk incorporation of fluorescein diacetate (FDAc) (model drug for paclitaxel (PTX)) via spray coating enhanced the subsequent cleavable surface coupling of vascular endothelial growth factor (VEGF) via the crosslinker bissulfosuccinimidyl suberate (BS 3 ). In the presence of the embedded FDAc, the VEGF loading and release are about twice times higher than in absence. Furthermore, the DDDS combines the diffusion drug delivery (FDAc or PTX) and the chemical controlled drug release, VEGF via hydrolysable ester bonds, without loss in quantity and quality of the drug release curves. Additionally, the performed in vitro biocompatibility study showed the bimodal influences of PTX and VEGF on human endothelial EA.hy926 cells. In conclusion, it was possible to show the feasibility to develop a novel DDDS which has a high potential for the medical application due to the possible easy and short modification of a polymer-based PTX delivery system.

  4. The Atlantic divide in coronary heart disease: Epidemiology and patient care in the US and Portugal.

    Science.gov (United States)

    Lobo, Mariana F; Azzone, Vanessa; Resnic, Frederic S; Melica, Bruno; Teixeira-Pinto, Armando; Azevedo, Luís Filipe; Freitas, Alberto; Nisa, Cláudia; Bacelar-Nicolau, Leonor; Rocha-Gonçalves, Francisco Nuno; Pereira-Miguel, José; Costa-Pereira, Altamiro; Normand, Sharon-Lise

    2017-09-01

    We aimed to compare access to new health technologies to treat coronary heart disease (CHD) in the health systems of Portugal and the US, characterizing the needs of the populations and the resources available. We reviewed data for 2000 and 2010 on epidemiologic profiles of CHD and on health care available to patients. Thirty health technologies (16 medical devices and 14 drugs) introduced during the period 1980-2015 were identified by interventional cardiologists. Approval and marketing dates were compared between countries. Relative to the US, Portugal has lower risk profiles and less than half the hospitalizations per capita, but fewer centers per capita provide catheterization and cardiothoracic surgery services. More than 70% of drugs were available sooner in the US, whereas 12 out of 16 medical devices were approved earlier in Portugal. Nevertheless, at least five of these devices were adopted first or diffused faster in the US. Mortality due to CHD and myocardial infarction (MI) was lower in Portugal (CHD: 72.8 vs. 168 and MI: 48.7 vs. 54.1 in Portugal and the US, respectively; age- and gender-adjusted deaths per 100000 population, 2010); but only CHD deaths exhibited a statistically significant difference between the countries. Differences in regulatory mechanisms and price regulations have a significant impact on the types of health technologies available in the two countries. However, other factors may influence their adoption and diffusion, and this appears to have a greater impact on mortality, due to acute conditions. Copyright © 2017 Sociedade Portuguesa de Cardiologia. Publicado por Elsevier España, S.L.U. All rights reserved.

  5. Zilver PTX Post-Market Surveillance Study of Paclitaxel-Eluting Stents for Treating Femoropopliteal Artery Disease in Japan: 12-Month Results.

    Science.gov (United States)

    Yokoi, Hiroyoshi; Ohki, Takao; Kichikawa, Kimihiko; Nakamura, Masato; Komori, Kimihiro; Nanto, Shinsuke; O'Leary, Erin E; Lottes, Aaron E; Snyder, Scott A; Dake, Michael D

    2016-02-08

    This multicenter, prospective, post-market surveillance study in Japan evaluates the paclitaxel-coated Zilver PTX stent in real-world patients with complex lesions. The Zilver PTX stent is the first drug-eluting stent (DES) approved for the superficial femoral artery. Previously, results from a large randomized study and a complementary, large single-arm study supported the safety and effectiveness of the DES. There were no exclusion criteria, and consecutive patients with symptomatic peripheral artery disease (PAD) treated with the DES were enrolled in the study. Clinically driven target lesion revascularization (TLR) was defined as reintervention performed for ≥50% diameter stenosis after recurrent clinical symptoms of PAD. Clinical benefit was defined as freedom from persistent or worsening symptoms of ischemia. Patency was evaluated by duplex ultrasound where physicians considered this standard of care. In this study, 907 patients were enrolled at 95 institutions in Japan. There were numerous comorbidities including high incidences of diabetes (58.8%), chronic kidney disease (43.8%), and critical limb ischemia (21.5%). Lesions were also complex, with an average length of 14.7 cm, 41.6% total occlusions, and 18.6% in-stent restenosis. In total, 1,861 DES were placed in 1,075 lesions. Twelve-month follow-up was obtained for >95% of eligible patients. Freedom from TLR was 91.0%, and clinical benefit was 87.7% through 12 months. The 12-month primary patency rate was 86.4%. Despite more challenging lesions, results from the current study are similar to outcomes from the previous Zilver PTX studies, confirming the benefit of the Zilver PTX DES in a real-world patient population. (Zilver PTX Post-Market Study in Japan; NCT02254837). Copyright © 2016 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

  6. Renewable Energy Policy Fact sheet - Portugal

    International Nuclear Information System (INIS)

    2017-07-01

    The EurObserv'ER policy profiles give a snapshot of the renewable energy policy in the EU Member States. In Portugal, electricity from renewable sources from existing plants is mainly promoted through a feed-in tariff. Support to new RES plants can currently only be remunerated through the open energy market. For RES-H there is currently no direct support mechanism or fiscal benefit in place (as of January 2017); only indirect support. In the transport sector, the main incentives are a bio-fuel quota system and a tax exemption to small producers of bio-fuels

  7. CERN and Portugal

    International Nuclear Information System (INIS)

    Anon.

    1995-01-01

    In its continual tour of CERN Member States, the European Committee for Future Accelerators (ECFA) visited Lisbon, Portugal, on 21-22 April, where it met at the Instituto Superiore Tecnico, a technical university with 9,000 students. Portuguese particle physics is in a particularly healthy situation, having developed considerably following Portugal's admission to CERN in 1985. With support from Brussels, scientific infrastructure has developed rapidly, although the science base has yet to attain the levels seen in larger nations. The 45-strong population of experimentalists in Portugal, including 14 PhDs, represents a 2.5-fold increase since Portugal joined CERN ten years ago and is in line with the goal stated at the time. This successful development of experimental particle physics has benefited much from physicists returning from abroad (mainly France and the UK). The direct result of the efforts of a few individuals (notably J.M. Gago), this splendid achievement provides an excellent role model for new and potential CERN Member States. At present, particle physics represents some 3 0% of all Portuguese physics publications. This very special role (and the financial support it implies) provides a visible target, but one which can be defended as it provides a catalyst for other national scientific developments. The national hub is the Laboratory for experimental high energy physics and related R&D projects (LIP), with centres in Lisbon (Head, J.M. Gago) and Coimbra (Head, A. Policarpo). LIP, with close links to two universities in Lisbon and to the University of Coimbra, has developed into a centre of expertise and training in electronics, computing and software engineering. Present LIP funding is some 2 million Swiss francs/year (70% in Lisbon and 3 0% in Coimbra), covering most of the salaries of the nonuniversity people, the remainder being supported by grants from Portuguese and European programmes. Portugal's contribution to CERN's 1995 budget

  8. Biosystems Engineering in Portugal

    OpenAIRE

    Marques da Silva, José Rafael; Silva, Luis Leopoldo; Cruz, Vasco Fitas

    2008-01-01

    The paper gives the definition of Biosystems Engineering in Portugal; Possible revisions of the core curriculum presented in the FEANI report; the current situation of Biosystems Engineering in Portugal; The impacts of the transition to Biosystems Engineering; The need for a transition to Biosystems Engineering;Opportunities to the Biosystems Engineer in the labour market.

  9. Portugal's Petrogal eyes expansion amid continuing privatization

    International Nuclear Information System (INIS)

    Anon.

    1995-01-01

    Portugal's recently privatized state oil company Petrogal is about to embark on a major expansion worldwide. That comes against the backdrop of major change in Portugal's energy sector and the rocky road to Petrogal's partial privatization. Despite the controversy, there remain opportunities for foreign companies investing in Portugal's energy sector. The most attractive opportunities are in Portugal's downstream petroleum sector and in the country's continuing campaign to develop its natural gas industry. Typical of the latter is Portugal's participation in the Trans-Maghreb gas pipeline megaproject. The paper discusses the background to privatization, its current status, Petrogal strategy, modernization of refineries, a joint partnership with Venezuela, constraints, energy policy program, gas pipeline privatization, and concerns of the gas industry

  10. La contabilidad pública en Portugal

    OpenAIRE

    Alberto Pedrosa, Fernanda

    2014-01-01

    LA CONTABILIDAD PÚBLICA EN PORTUGAL - Que se entiende por Sector Público - Arquitectura del Sector Público en Portugal. - Evolución de la Contabilidad del Sector Público en Portugal. - El Plan Oficial de Contabilidad Pública (POCP) y Planes de Contabilidad sectoriales. - Las normas de consolidación de cuentas en el Sector Público. - Y hoy, ¿cuál es el punto de la situación? Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech.

  11. España, Portugal y los falsos amigos | Spain, Portugal and the false friends

    Directory of Open Access Journals (Sweden)

    Ángel RIVERO RODRÍGUEZ

    2010-02-01

    Full Text Available España y Portugal son dos países que comparten mucho en el terreno de la historia, la cultura y la geografía. Sin embargo, esa misma proximidad se ha convertido muchas veces en el principal obstáculo para que cooperen entre sí.Desde la perspectiva portuguesa, la proximidad española se ha visto permanentemente como una amenaza a la independencia de Portugal. Desde el punto de vista de España, la cercanía de Portugal ha debilitado su consideración como país extranjero y ha acentuado un sentido de comunidad no siempre bien recibido por los portugueses. De modo que Portugal siempre ha querido diferenciarse y España ha respondido siempre aproximándose. Esta es la raíz del malentendido.Este cruce de percepciones distintas sobre el valor de proximidad, da lugar a todo tipo de equívocos, pues el deseo de diferenciación de uno puede entenderse como enemistad por el otro y, a la inversa, el de aproximación del segundo como invasión por el primero. Ejemplo de esto es lo que ocurre con la palabra iberismo, una palabra que se escribe igual en ambas lenguas pero que puede significar cosas opuestas, esto es, que puede ser un falso amigo. Así en las dos lenguas iberismo señala el ideal de una integración de ambos países, pero en portugués esto implica la subordinación de la soberanía portuguesa a la española y puede vincularse a la idea de traición; mientras que en español tiene una carga política mucho menor y puede apuntar a la simple simpatía por Portugal.En este artículo quiero mostrar cómo la proximidad de España y Portugal ha sido un obstáculo en las relaciones exteriores entre los dos países peninsulares, cuya comunicación ha sido distorsionada por los falsos amigos hasta el punto de convertirse, ellos mismos, en falsos amigos. Esto es, en países a los que se presupone una cercanía de propósitos que casi nunca se ve realizada en los hechos. Portugal and Spain are two countries that share history, culture and

  12. The natural gas industry in Portugal

    International Nuclear Information System (INIS)

    Kheloufi, S.

    2004-01-01

    This article makes a synthesis of the evolution of the natural gas sector in Portugal since the end of the 1990's. The aim of the energy policy of Portugal was the creation of a liberalized energy market capable to ensure the security of the energy supplies and to encourage the energy efficiency in order to reduce the environmental impact. The success of the introduction of natural gas in Portugal perfectly fulfills these goals. Since 1997, the natural gas consumption has increased significantly. The start-up of the methane terminal of Sines allows the diversification of the supply sources and contributes to the growth of the offer. The opening of the market is under development. It will allow the main consumers to select their supplier among those present on the Portuguese market. GALP company should keep its leader position and its daughter company 'Gas du Portugal' should reach 300 MW of power generation capacities by 2005 with the development of multi-energy services. The creation of an Iberian energy market between Spain and Portugal should speed up in 2004 leading to deep modifications in the energy sector of southern Europe. (J.S.)

  13. The differential role of social networks. Strategies and routes in Brazilian migration to Portugal and the Netherlands

    NARCIS (Netherlands)

    M.J. van Meeteren (Masja); S. Pereira (Sonia)

    2013-01-01

    textabstractAbstract This paper draws on qualitative and quantitative data on the migration experiences of Brazilians living in Portugal and the Netherlands to reflect and expand upon the existing knowledge on the role of social networks in migration processes. We consider different migrant profiles

  14. Optometry in Portugal: a historical perspective

    Science.gov (United States)

    Teixeira, Eduardo; Baptista, António M. G.; Sousa, Raul A. R. C.

    2011-05-01

    The establishment and development of optometry in Portugal resulted from the committed work of many individuals and institutions. These efforts have had good results in terms of raising the public's awareness of the major role played by optometrists in primary eye care. Back in the late 80's higher education in optometry was started. Ten years ago the results of scientific research on the topic first became available and are now also contributing to the success of optometry in Portugal. In regard to the optometry profession, specific regulations are to be discussed in the national parliament. The Associação de Profissionais Licenciados de Optometria (APLO), as the professional organization representing optometrists in Portugal, has been critically important in this process. This article will present an overview of the history of optometry in Portugal, of change in the foreseeable future and of the APLO's experience and activities.

  15. CHINESE ENTREPRENEURIAL ACTIVITY IN PORTUGAL: TRADITIONAL ETHNIC STRATEGIES?

    Directory of Open Access Journals (Sweden)

    Catarina Reis Oliveira

    2010-12-01

    Full Text Available In Portugal in recent decades, just like in other welcoming countries, immigrants have reached levels of entrepreneurial activity that are higher than those of autochthonous citizens. However, a deeper analysis of the official data shows that not all immigrant groups have the same tendency to become entrepreneurs. In this respect, the Chinese stand out as being the group with the highest ratio of entrepreneurial activity in Portugal, despite the fact that their migration is a relatively recent phenomenon. What factors can explain the Chinese community’s disproportionate rate of entrepreneurial initiative? Do they possess any particular resources that make them more enterprising than the autochthonous population, or than other groups of immigrants? Does the context of Portugal hamper certain opportunities or in some way limit their economic integration into the job market? Do we find similar business strategies among other Chinese entrepreneurs residing in welcoming societies apart from that of Portugal? Why did Chinese business initiative grow at such an exceptional rate in Portugal in the late 1990s? By seeking answers to these questions, this article attempts to examine Chinese business strategies in Portugal, as well as their exceptional success rate in comparison with other entrepreneurial immigrants. To that end, the author has analysed the data gathered in a survey carried out on 309 Chinese entrepreneurs resident in Portugal (see Oliveira, 2005.

  16. Transnational citizenship: Latin Americans in Portugal

    Directory of Open Access Journals (Sweden)

    Beatriz Padilla

    2014-09-01

    Full Text Available This article is a reflection upon the exercising of transnational citizenship as a consequence of international migration, applied to Latin Americans resident in Portugal. In order to do this we have adopted the concept of transnational citizenship, as its malleability allows us to consider the whole concept of countries of origin and destination and the influence of bilateral and international relations. We ask how transnational citizenship is exercised in the European Union, Ibero-American and, particularly, Portuguese spaces, and whether it is affected by the economic crisis in Europe and, in particular, Portugal, by analysing the cases of Argentines, Brazilians and Uruguayans living in Portugal.

  17. Portugal

    International Nuclear Information System (INIS)

    2001-03-01

    This short report summarizes the main lines of the energy policy of Portugal. It presents the main energy companies and utilities (EDP, CPPE, REN, Petrogal, GDP, Galp SGPS) of the country, the energy supplies (resources, electricity, petroleum, coal, natural gas), the prices and pricing policy, the global energy consumption per sector, the stakes and perspectives of the energy market (forecasts, contracts). (J.S.)

  18. Computer Tomography Scanners in Portugal (1990-2011

    Directory of Open Access Journals (Sweden)

    Ricardo Crispim

    2014-06-01

    Full Text Available The use of Computed Tomography (CT has increased every year since its introduction into medicine in 1972. Technological developments have made CT one of the most important imaging modalities in modern medicine. This importance is evidenced in the increasing demand and number of CT scanners installed in Portugal and worldwide. This review compiles the most recent national statistics from official publications on the number of CT scanners installed in Portugal and compares them with data available in international publications. We conclude that the number of CT scanners installed in Portugal exceeded the EU27 average by 61.5 % and the OECD average by 78.2 %, and that in 2011 there were 203 CT scanners installed in hospitals in Portugal, which equated to 19.23 CT scanners per million inhabitants.

  19. Tourism research in Portugal: a contribution to its characterization

    Directory of Open Access Journals (Sweden)

    João Albino Silva

    2013-12-01

    Full Text Available This work intends to be a first contribution to the characterization of tourism research in Portugal, focusing on the researcher’s profile and the characteristics of research. To that end, and based on a national Tourism Research, it was possible to identify 166 researchers working in this area, spread over about 30 higher education institutions, who subsequently completed an online questionnaire. Data were collected during March 2013 and 111 valid responses were obtained. The results show a growing and predominantly young scientific community and also highlight a diverse, solid and stimulating disciplinary perspective.

  20. The Plasmoid Thruster Experiment (PTX)

    Science.gov (United States)

    Eskridge, Richard; Martin, Adam; Koelfgen, Syri; Lee, Mike; Smith, James W.

    2003-01-01

    A plasmoid is a compact plasma structure with an integral magnetic field. They have been studied extensively in controlled fusion research and are categorized according to the relative strength of the poloidal and toroidal magnetic field (B(phi), and B(tau), respectively). An object with B(phi)/B(tau) >> 1 is classified as a Field Reverse Configuration (FRC); if B(phi) = B(tau), it is called a Spheromak. There are a number of possible advantages to using accelerated plasmoids for in-space propulsion. A thruster based on this concept would operate by repetitively producing plasmoids and ejecting them from the device at high velocity. The plasmoid is formed inside of a single turn conical theta-pinch coil; as this process is inductive, there are no life-limiting electrodes. Similar experiments have yielded plasmoid velocities of at least 50 km/s (l), and calculations indicate that velocities in excess of 100 km/s are possible. A thruster based on this concept would be capable of producing an I(sp) in the range of 5,000 - 10,OOO s, with thrust densities of order 10(exp 5) N/m(exp 2). The current experiment is designed to produce jet powers in the range of 5-10 kW, although the concept should be scalable to higher power. The purpose of this experiment is to determine the feasibility of this plasma propulsion concept. To accomplish this, it will be necessary to determine: a.) specific impulse and thrust, b.) efficiency and mass utilization, c.) which type of plasmoid (FRC-like or Spheromak-like) gives the best performance, and d.) the characteristics required of actual thruster components (i.e., switch and capacitor technology). The plasmoid mass and velocity will be measured with a variety of diagnostics, including internal and external B-dot probes, flux loops, Langmuir probes, high-speed cameras, and an interferometer. Simulations of the plasmoid thruster using MOQUI, a time dependent MHD code, will be carried out concurrently with experimental testing. The PTX

  1. Lessons from wind policy in Portugal

    Energy Technology Data Exchange (ETDEWEB)

    Peña, Ivonne; L. Azevedo, Inês; Marcelino Ferreira, Luís António Fialho

    2017-04-01

    Wind capacity and generation grew rapidly in several European countries, such as Portugal. Wind power adoption in Portugal began in the early 2000s, incentivized by a continuous feed-in tariff policy mechanism, coupled with public tenders for connection licenses in 2001, 2002, and 2005. These policies led to an enormous success in terms of having a large share of renewables providing electricity services: wind alone accounts today for ~23.5% of electricity demand in Portugal. We explain the reasons wind power became a key part of Portugal's strategy to comply with European Commission climate and energy goals, and provide a detailed review of the wind feed-in tariff mechanism. We describe the actors involved in wind power production growth. We estimate the environmental and energy dependency gains achieved through wind power generation, and highlight the correlation between wind electricity generation and electricity exports. Finally, we compare the Portuguese wind policies with others countries' policy designs and discuss the relevance of a feed-in tariff reform for subsequent wind power additions.

  2. Vocational Profiles and Training Requirements of Foremen and Overseers in the Textile/Clothing Sector in Portugal.

    Science.gov (United States)

    Pereira, Licinio Chainho; And Others

    A study examined the current needs of middle management in the textile and clothing industry in Portugal. Focus was on Level 3--foremen, overseers, and team leaders. Eight of 400 enterprises responded to the first questionnaire; 370 of 1,000 responded to the revised questionnaire. The following data were collected: number of employees according to…

  3. The cavernicolous Oniscidea (Crustacea: Isopoda) of Portugal

    DEFF Research Database (Denmark)

    P. S. Reboleira, Ana Sofia; Gonçalves, Fernando J.; Oromí, Pedro

    2015-01-01

    The study of subterranean Oniscidea in Portugal has been neglected for nearly 70 years, but recent investigations have revealed high diversity. All the terrestrial isopods known from caves of mainland Portugal, including data from the literature and new material, are listed, revealing new biodive...

  4. Synchrotron Based Structural Investigations of Mass-Selected PtxGd Nanoparticles and a Gd/Pt(111) Single Crystal for Electrochemical Oxygen Reduction

    DEFF Research Database (Denmark)

    Pedersen, Anders Filsøe; Velazquez-Palenzuela, Amado Andres; Masini, Federico

    2015-01-01

    . 134, 16476–16479 (2012). 3. Velazquez-Palenzuela, A. et al. The enhanced activity of mass-selected PtxGd nanoparticles for oxygen electroreduction. J. Catal. [in press] (2015). doi:10.1016/j.jcat.2014.12.012 4. Perez-Alonso, F. J. et al. The Effect of Size on the Oxygen Electroreduction Activity...

  5. Padrões de casamento dos imigrantes brasileiros residentes em Portugal Patrones de matrimonio de los inmigrantes brasileños residentes en Portugal Marriage patterns of Brazilian immigrants living in Portugal

    Directory of Open Access Journals (Sweden)

    Ana Cristina Ferreira

    2012-12-01

    Full Text Available Ao longo das últimas décadas, o número de estrangeiros residentes em Portugal aumentou de forma expressiva. Neste contexto, a comunidade brasileira assumiu uma importância cada vez maior, sendo em 2009 a nacionalidade mais representada, com uma participação de 25% no total de residentes estrangeiros em Portugal. Esta evolução tem, como seria de se esperar, reflexos a outros níveis, em particular no contexto do casamento. Contrariando a tendência decrescente observada para o total de casamentos ocorridos entre 2001 e 2009, aqueles em que pelo menos um dos cônjuges nasceu no Brasil quase quadruplicaram nesse período. Para muitos autores, os casamentos mistos são um bom indicador da integração das comunidades imigrantes na sociedade de acolhimento. Assim, dada a importância da comunidade brasileira residente em Portugal, é relevante observar qual o peso dos casamentos mistos nesta comunidade e analisar seus padrões de matrimônio. A análise estatística dos microdados dos casamentos disponibilizados pelo Instituto Nacional de Estatística possibilitou estudar e caraterizar a evolução dos casamentos registrados em Portugal, entre 2001 e 2009, envolvendo brasileiros residentes em Portugal. Ficou patente a existência de um elevado nível de casamentos mistos, em especial com portugueses, neste período, o que indicia sua integração na comunidade de acolhimento. Verificaram-se igualmente algumas diferenças nos padrões de matrimônio entre os sexos, bem como uma tendência para a diminuição da importância dos casamentos mistos, em especial entre os homens.A lo largo de las últimas décadas, el número de extranjeros residentes en Portugal aumentó de forma expresiva. En este contexto, la comunidad brasileña asumió una importancia cada vez mayor, siendo en 2009 la nacionalidad más representativa, con una cuota de residentes del 25% en el total de población extranjera en Portugal. Esta evolución tiene, como cabr

  6. Enoturismo em Portugal: as Rotas de Vinho

    Directory of Open Access Journals (Sweden)

    Simões, Orlando

    2008-04-01

    Full Text Available Since 1993, as supported by the Dyonisios program of the European Union, the wine routes have been the most visible face of the wine tourism practice in Portugal. Since these thematic routes have no specific rules, they usually depend on the initiative of the promoters, namely through the creation of adherent/promoters associations or other institutions, like the Regional Viticulture Commissions, and Tourism Regions. This article aims at analysing the basis for the development of wine tourism in Portugal and its structure around wine routes. The socioeconomics traits of both the vineyards and wine, are analysed. The existing routes in Portugal are presented and their strengths and limitations are identi-fied.

  7. Child Labour and Educational Success in Portugal

    Science.gov (United States)

    Goulart, Pedro; Bedi, Arjun S.

    2008-01-01

    The current debate on child labour focuses on developing countries. However, Portugal is an example of a relatively developed country where child labour is still a matter of concern as between 8% and 12% of Portuguese children may be classified as workers. This paper studies the patterns of child labour in Portugal and assesses the consequences of…

  8. How can Portugal attract more China´S young generation tourists?

    OpenAIRE

    Liu, Yujing

    2017-01-01

    Portugal as a tourism destination has great potential to be further developed, however it is still not well known by the Chinese outbound tourists, especially the young generation who would stay longer and spend more in Portugal. This paper describe the current situation of Portugal tourism in Chinese outbound market, after analyzing explained why Portugal should aim at the young generation, and finally gave some recommendations of how to attract them, mainly through social media platforms.

  9. Relationship between Sustained Reductions in Plasma Lipid and Lipoprotein Concentrations with Apheresis and Plasma Levels and mRNA Expression of PTX3 and Plasma Levels of hsCRP in Patients with HyperLp(alipoproteinemia

    Directory of Open Access Journals (Sweden)

    Claudia Stefanutti

    2016-01-01

    Full Text Available The effect of lipoprotein apheresis (Direct Adsorption of Lipids, DALI (LA on plasma levels of pentraxin 3 (PTX3, an inflammatory marker that reflects coronary plaque vulnerability, and expression of PTX3 mRNA was evaluated in patients with hyperLp(alipoproteinemia and angiographically defined atherosclerosis/coronary artery disease. Eleven patients, aged 55±9.3 years (mean ± SD, were enrolled in the study. PTX3 soluble protein levels in plasma were unchanged by 2 sessions of LA; however, a downregulation of mRNA expression for PTX3 was observed, starting with the first session of LA (p<0.001. The observed reduction was progressively increased in the interval between the first and second LA sessions to achieve a maximum decrease by the end of the second session. A statistically significantly greater treatment-effect correlation was observed in patients undergoing weekly treatments, compared with those undergoing treatment every 15 days. A progressive reduction in plasma levels of C-reactive protein was also seen from the first session of LA, with a statistically significant linear correlation for treatment-effect in the change in plasma levels of this established inflammatory marker (R2=0.99; p<0.001. Our findings suggest that LA has anti-inflammatory and endothelium protective effects beyond its well-established efficacy in lowering apoB100-containing lipoproteins.

  10. Portugal to Accede to ESO

    Science.gov (United States)

    2000-06-01

    The Republic of Portugal will become the ninth member state of the European Southern Observatory (ESO) [1]. Today, during a ceremony at the ESO Headquarters in Garching (Germany), a corresponding Agreement was signed by the Portuguese Minister of Science and Technology, José Mariano Gago and the ESO Director General, Catherine Cesarsky , in the presence of other high officials from Portugal and the ESO member states (see Video Clip 05/00 below). Following subsequent ratification by the Portuguese Parliament of the ESO Convention and the associated protocols [2], it is foreseen that Portugal will formally join this organisation on January 1, 2001. Uniting European Astronomy ESO PR Photo 16/00 ESO PR Photo 16/00 [Preview - JPEG: 400 x 405 pix - 160k] [Normal - JPEG: 800 x 809 pix - 408k] Caption : Signing of the Portugal-ESO Agreement on June 27, 2000, at the ESO Headquarters in Garching (Germany). At the table, the ESO Director General, Catherine Cesarsky , and the Portuguese Minister of Science and Technology, José Mariano Gago . In his speech, the Portuguese Minister of Science and Technology, José Mariano Gago , stated that "the accession of Portugal to ESO is the result of a joint effort by ESO and Portugal during the last ten years. It was made possible by the rapid Portuguese scientific development and by the growth and internationalisation of its scientific community." He continued: "Portugal is fully committed to European scientific and technological development. We will devote our best efforts to the success of ESO". Catherine Cesarsky , ESO Director General since 1999, warmly welcomed the Portuguese intention to join ESO. "With the accession of their country to ESO, Portuguese astronomers will have great opportunities for working on research programmes at the frontiers of modern astrophysics." "This is indeed a good time to join ESO", she added. "The four 8.2-m VLT Unit Telescopes with their many first-class instruments are nearly ready, and the VLT

  11. Lessons from wind policy in Portugal

    International Nuclear Information System (INIS)

    Peña, Ivonne; Azevedo, Inês L.; Marcelino Ferreira, Luís António Fialho

    2017-01-01

    Wind capacity and generation grew rapidly in several European countries, such as Portugal. Wind power adoption in Portugal began in the early 2000s, incentivized by a continuous feed-in tariff policy mechanism, coupled with public tenders for connection licenses in 2001, 2002, and 2005. These policies led to an enormous success in terms of having a large share of renewables providing electricity services: wind alone accounts today for ~23.5% of electricity demand in Portugal. We explain the reasons wind power became a key part of Portugal’s strategy to comply with European Commission climate and energy goals, and provide a detailed review of the wind feed-in tariff mechanism. We describe the actors involved in wind power production growth. We estimate the environmental and energy dependency gains achieved through wind power generation, and highlight the correlation between wind electricity generation and electricity exports. Finally, we compare the Portuguese wind policies with others countries’ policy designs and discuss the relevance of a feed-in tariff reform for subsequent wind power additions. - Highlights: • Portugal relies on feed-in tariffs as the key mechanism for wind diffusion. • Wind generation accounts for a quarter of total electricity generation. • The current feed-in tariffs system is not economically efficiency. • A feed-in tariff reform should be considered.

  12. The Counter-Reformation, Diplomacy, and Art Patronage in Portugal under Cardinal-Infant D. Henrique of Portugal: A Legacy to Serve Church and Kingdom

    Directory of Open Access Journals (Sweden)

    Milton Pedro Dias Pacheco

    2017-12-01

    Full Text Available Commonly known as the Cardinal-King, Don Henrique of Portugal was a Portuguese royal-blood infant who was destined to become a prince of the Church. He was a preeminent figure of the sixteenth century: the period of the political, economic, religious, and cultural expansion of the Portuguese Empire, and of the Counter-Reformation. During his service to the Roman Catholic Church, D. Henrique occupied the seats of the three Portuguese archdioceses, was chosen to govern some of the wealthiest religious orders, and represented the Holy Office in Portugal. He was also nominated cardinal and legate a latere to Portugal. The Cardinal-Infant was responsible for an unprecedented architectural innovation in Portugal and beyond, reforming, expanding, and erecting several buildings. This study focuses on the institutional projects and material reforms in Portugal initiated by Cardinal-King D. Henrique through complex diplomatic relations between the Portuguese Crown and the Holy See during the sixteenth century. Its main objective is to create a basis for further research into his architectural patronage while occupying his several positions of ecclesiastical and lay authority.

  13. Introducción de las artes marciales asiáticas en Portugal = The introduction of asian martial arts in Portugal

    Directory of Open Access Journals (Sweden)

    Carlos Gutiérrez García

    2013-03-01

    Full Text Available El presente estudio analiza la introducción del jujutsu en Portugal, sucedida a principios del siglo XX. Para su realización se ha consultado fundamentalmente prensa histórica portuguesa, tanto general como específica del ámbito deportivo. Los resultados obtenidos muestran que la introducción del jujutsu en Portugal se produjo fundamentalmente a través del mundo del espectáculo, mediante actuaciones de expertos japoneses. Las notables diferencias técnicas y corporales entre estos luchadores japoneses y los luchadores profesionales de lucha libre y grecorromana de la época, a los que habitualmente solían derrotar, contribuyeron a generar un potente imaginario de las artes de combate orientales como sistemas superiores de cultura física y defensa personal. No obstante, a pesar del éxito del jujutsu este no logró afianzarse sólidamente en Portugal, desapareciendo progresivamente de la escena pública desde principios de la segunda década del siglo XX.-------------------------------------------------------------------------------The present study analyzes the introduction of jujutsu in Portugal at the beginning of the 20th century. Mainly, historical Portuguese newspapers were reviewed, both general and specific from sports field. Results show that the introduction of jujutsu in Portugal was principally conduced via the show business through exhibitions performed by Japanese experts. Significant technical and physical differences between the Japanese fighters and the professional Freestyle and Greco-roman fighters, who were usually defeated by the former, contributed to create a powerful imaginary of the eastern fighting arts as superior systems of physical culture and self-defence. However, in spite of jujutsu’s success, it did not come to be strongly established in Portugal, vanishing progressively off the public scene since the beginning of the 1910s.

  14. Plasma aminothiol profile and some of its determinants in subjects from the Azores Archipelago, Portugal

    OpenAIRE

    Lima, Ana Patrícia Rego

    2011-01-01

    Dissertação de Mestrado em Ciências Biomédicas Comparados com Portugal Continental, os Açores possuem as mais altas taxas de mortalidade padronizadas por doenças cardiovasculares (CVD), cuja principal causa é a aterosclerose. Geralmente, os sintomas só surgem em fases avançadas da doença, havendo necessidade de encontrar marcadores precoces e não invasivos. Os aminotióis, tais como a homocisteína (Hcy), a cisteína (Cys), a cisteinil-glicina (Cys-Gly) e o glutationo (GSH) são componentes in...

  15. Post Fire Vegetation Recovery in Portugal

    Science.gov (United States)

    Gouveia, Celia; Bastos, Ana; DaCamara, Carlos; Trigo, Ricardo M.

    2011-01-01

    Fires in Portugal, as in the Mediterranean ecosystems, have a complex effect on vegetation regeneration due to the different responses of vegetation to the variety of fire regimes and to the complexity of landscape structures. A thorough evaluation of vegetation recovery after fire events becomes therefore crucial in land management. In 2005, Portugal suffered a strong damage from forest fires that damaged an area of 300 000 ha of forest and shrub. This year are particularly interesting because it is associated the severe drought of 2005. The aim of the present study is to identify large burnt scars in Portugal during the 2005 fire seasons and monitoring vegetation behaviour throughout the pre and the post fire periods. The mono-parametric model developed by Gouveia et al. (2010), based on monthly values of NDVI, at the 1km×1km spatial scale, as obtained from the VEGETATION-SPOT5 instrument, from 1999 to 2009, was used.

  16. Portugal Democrático: An Exiles’ Newspaper

    Directory of Open Access Journals (Sweden)

    Isabel Travancas

    2017-12-01

    Full Text Available The purpose of this article is to present the newspaper Portugal Democrático (Democratic Portugal through its history, its style and format. It is a periodical publication produced in São Paulo by Portuguese exiles during the dictatorship of Antônio Salazar (1926-1974. The newspaper began to circulate in 1956 and came to an end in 1975, a year after the Carnation Revolution that occurred on April 25, 1974. Fighting the Salazar dictatorship outside Portugal was the reason for the creation of the newspaper in Brazil, where it also had the collaboration of Brazilian journalists and intellectuals. This paper analyzes the newspaper Portugal Democrático both in its political aspect and in its editorial feature and concludes that the paper played a greater role than informative. It was an important part of the international opposition movement and resistance to Salazar's dictatorial regime. O objetivo deste artigo é apresentar o jornal Portugal Democrático através de sua história, de seu estilo e formato. Trata-se de uma publicação periódica produzida em São Paulo por exilados portugueses durante a ditadura de Antônio Salazar (1926-1974. O jornal começou a circular em 1956 e chegou ao fim em 1975, um ano depois da Revolução dos Cravos ocorrida em 25 de abril de 1974. Lutar contra a ditadura salazarista fora de Portugal foi o motivo da criação do jornal no Brasil, onde contou com a colaboração de jornalistas e intelectuais brasileiros. O trabalho analisa o jornal Portugal Democrático tanto em seu aspecto político quanto em sua feição editorial e conclui que o periódico teve um papel maior do que informativo. Ele foi parte importante no movimento internacional de oposição e resistência ao regime ditatorial de Salazar. El objetivo de este artículo es dar a conocer el periódico Portugal Democrático a través de su historia, de su estilo y formato. Se trata de una publicación periódica producida en São Paulo por los

  17. Relationship between Sustained Reductions in Plasma Lipid and Lipoprotein Concentrations with Apheresis and Plasma Levels and mRNA Expression of PTX3 and Plasma Levels of hsCRP in Patients with HyperLp(a)lipoproteinemia

    Science.gov (United States)

    Stefanutti, Claudia; Mazza, Fabio; Steiner, Michael; Watts, Gerald F.; De Nève, Joel; Pasqualetti, Daniela; Paal, Juergen

    2016-01-01

    The effect of lipoprotein apheresis (Direct Adsorption of Lipids, DALI) (LA) on plasma levels of pentraxin 3 (PTX3), an inflammatory marker that reflects coronary plaque vulnerability, and expression of PTX3 mRNA was evaluated in patients with hyperLp(a)lipoproteinemia and angiographically defined atherosclerosis/coronary artery disease. Eleven patients, aged 55 ± 9.3 years (mean ± SD), were enrolled in the study. PTX3 soluble protein levels in plasma were unchanged by 2 sessions of LA; however, a downregulation of mRNA expression for PTX3 was observed, starting with the first session of LA (p < 0.001). The observed reduction was progressively increased in the interval between the first and second LA sessions to achieve a maximum decrease by the end of the second session. A statistically significantly greater treatment-effect correlation was observed in patients undergoing weekly treatments, compared with those undergoing treatment every 15 days. A progressive reduction in plasma levels of C-reactive protein was also seen from the first session of LA, with a statistically significant linear correlation for treatment-effect in the change in plasma levels of this established inflammatory marker (R 2 = 0.99; p < 0.001). Our findings suggest that LA has anti-inflammatory and endothelium protective effects beyond its well-established efficacy in lowering apoB100-containing lipoproteins. PMID:26903710

  18. Reconstruindo memórias: jovens refugiados em Portugal Rebuilding memories: young refugees in Portugal

    Directory of Open Access Journals (Sweden)

    Maria Cristina Santinho

    2009-12-01

    Full Text Available O presente ensaio foi apresentado em setembro de 2007, no contexto do Seminário Internacional "Programa de Cooperação em Ciências Sociais para os Países da CPLP", promovido pela LIESP - Laboratório Interdisciplinar de Estudos e Pesquisas Sociais em Saúde Pública, Faculdade de Saúde Pública, Universidade de São Paulo. Resulta de um work in progress conducente a uma tese de doutoramento em antropologia médica. Pretende apresentar a condição dos jovens refugiados e requerentes de asilo em Portugal, em particular na vertente da saúde mental. O trabalho de campo levado a cabo com estes jovens envolveu a escuta de muitas narrativas de sofrimento provocado pela sua experiência de vida nos contextos originais de guerra, com testemunhos de violência e tortura, e também as dificuldades sentidas no longo percurso de viagem de fuga e posterior inserção em Portugal. O isolamento, as barreiras linguísticas, a ausência de redes sociais e familiares de apoio e a dificuldade de encontrar, em Portugal, referentes socioculturais e simbólicos, comprometem o seu desenvolvimento enquanto jovens, levando-nos a equacionar o valor dos referentes identitários na construção do eu e até o próprio conceito de juventude.This essay was first presented in September 2007, within the seminar "Programa de Cooperação em Ciências Sociais para os Países da CPLP", promoted by LIESP - Faculdade de Saúde Pública, Universidade de São Paulo. It is a work in progress, leading to a PhD thesis on medical anthropology. It aims to present refugee's youth and asylum seeker's condition in Portugal, particularly in regard to mental health. The fieldwork conducted with these youth comprised active listening of their suffer narratives, provoked not only by life experiences in their original war contexts, with testimonies of violence and torture, but also the difficulties felt during the long flee journey and subsequent insertion in Portugal. Isolation, pain

  19. Soil properties and understory herbaceous biomass in forests of three species of Quercus in Northeast Portugal

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    Marina Castro

    2014-12-01

    Full Text Available Aim of study: This paper aims to characterize some soil properties within the first 25 cm of the soil profile and the herbaceous biomass in Quercus forests, and the possible relationships between soil properties and understory standing biomass.Area of study: Three monoespecific Quercus forests (Q. suber L., Q. ilex subsp. rotundifolia Lam. and Q. pyrenaica Willd in NE Portugal.Material and methods: During 1999 and 2000 soil properties (pH-KCl, total soil nitrogen (N, soil organic carbon (SOC, C/N ratio, available phosphorus (P, and available potassium (K and herbaceous biomass production of three forest types: Quercus suber L., Quercus ilex subsp. rotundifolia Lam. and Quercus pyrenaica Willd were studied.Main results: The results showed a different pattern of soil fertility (N, SOC, P, K in Quercus forests in NE of Portugal. The C/N ratio and the herbaceous biomass confirmed this pattern. Research highlights: There is a pattern of Quercus sp. distribution that correlates with different soil characteristics by soil characteristics in NE Portugal. Q. pyrenaica ecosystems were found in more favoured areas (mesic conditions; Q. rotundifolia developed in nutrient-poor soils (oligotrophic conditions; and Q. suber were found in intermediate zones.Keywords: fertility; biomass; C/N ratio; cork oak; holm oak; pyrenean oak.

  20. Analysis of fatal accidents with tractors in the Centre of Portugal: Ten years analysis.

    Science.gov (United States)

    Antunes, Soraia M; Cordeiro, Cristina; Teixeira, Helena M

    2018-06-01

    Tractors have been described as one of the deadliest farming implements concerning agricultural activity. In Portugal, the scientific investigations about this problem are practically non-existent, with only statistical studies performed by entities related to road traffic safety, not in accordance to the study now performed, pinpointing the possibility of an underreporting of these accidents. This work aims to characterize the fatal tractor accidents in Portugal, autopsied at the Forensic Pathology Department of the Centre Branch of the National Institute of Legal Medicine and Forensic Sciences of Portugal, analysing several variables: gender, age, occupation, survival time, the victim position in the tractor, cause of death, toxicological and histological exams, year/month/day of the week, type of agricultural machine, existence of rollover protective structures (ROPS), type of accident, ground conditions, circumstantial information and geographic distribution of the accidents. All the autopsies between 2005 and 2014 were analysed. The victim profile corresponded to a man (89.5%), between 61 and 70 years old (33.3%), retired (43.9%), being the tractor driver (45.6%). In most of the cases, death occurred in less than 24h after the accident. These fatalities arose mainly in May and October. Rollover in sloping land was the most common type of accident, and cranioencephalic, thoracic and abdominal traumatic injuries were the main cause of death. In 16.2% of the cases, blood alcohol concentration was above the lower limit established in our road traffic law (accidents, and the corresponding circumstances that contributed to the death. Many barriers remain about this matter, but the Portuguese government begin to design several laws to prevent this type of accidents. Future investigations should be performed to understand the real dimension of tractor accidents in Portugal, and to comprehend the efficiency of laws implemented by the government. Copyright © 2018

  1. Portugal and United States cooperative energy assessment. Volume 3. Reference reports, Part 1

    Energy Technology Data Exchange (ETDEWEB)

    1981-09-01

    Statistical data on energy production and consumption and supporting information were obtained from US Bureau of Mines records supplemented by additional data obtained in Portugal. Geologic descriptions and analysis of known areas and of areas having possible future potential have been prepared by the US Geological Survey. Portugal lacks sufficient indigenous supplies of organic fuels to meet its energy demands, and so must import large quantities of petroleum and coal. Approximately 80% of Portugal's electric energy is produced by hydroelectric stations; thermal stations produce the other 20%. Portugal has produced no crude oil, natural gas, or condensate; no resources or reserves in these categories are listed for Portugal in the 1976 World Energy Conference report. Until the last year or so (1980), no significant onshore petroleum exploration had been done in Portugal since 1963. Production of coal in Portugal has declined steadily to the present annual yield of about 200,000 metric tons. On the basis of estimates in only three coal fields, resources of coal of all ranks in Portugal total at least 76 million (10/sup 6/) metric tons. Uranium is mined near Viseu and Guarda in the northern part of Portugal; the Nisa mine in east-central Portugal will begin producing uranium ore in 1985 after installation of a processing plant. Portugal produced 95 metric tons of uranium oxide (U/sub 3/O/sub 8/) from ore stocks in each year from 1972 through 1974; production is assumed to have continued at the same rate since then. Geothermal energy has not been developed in mainland Portugal; however, hot springs that may have geothermal energy potential are known in the Minho district in the northwest. Geothermal energy resources exist in the Azores and a program of evaluation and exploration with technical assistance from the USGS is presently in progress there.

  2. Exploring the Personality Traits of Portugal as a Tourist Destination: Perspective of the Czech Market

    Directory of Open Access Journals (Sweden)

    Manuela Guerreiro

    2015-06-01

    Full Text Available The personality of a destination is vital to build a coherent destination brand and strengthen the place identity. Furthermore, brand personality appears in literature as a strategic axis that can be explored by tourist destinations in order to differentiate themselves from competitors. Since a brand encompasses not only functional but also symbolic elements, its image, as perceived by consumers, can be assessed with respect to both its functional and psychological components. Hence, this exploratory study investigates the brand personality of Portugal as a tourist destination, from the perspective of the Czech market, through a destination image approach. The online survey instrument included open-ended items to depict functional and psychological destination features and additional questions to characterize the profile of a sample of Czech university students. The main findings of this research highlight positive personality traits that are related to the brand of Portugal, which suggest its potential as a vacation destination for the Czech market under study.

  3. Safety profile of solid lipid nanoparticles loaded with rosmarinic acid for oral use: in vitro and animal approaches

    Directory of Open Access Journals (Sweden)

    Madureira AR

    2016-08-01

    Full Text Available Ana Raquel Madureira,1 Sara Nunes,2 Débora A Campos,1 João C Fernandes,2 Cláudia Marques,3 Monica Zuzarte,2 Beatriz Gullón,1 Luís M Rodríguez-Alcalá,1 Conceição Calhau,3,4 Bruno Sarmento,5–7 Ana Maria Gomes,1 Maria Manuela Pintado,1 Flávio Reis2 1Catholic University of Portugal, CBQF – Center for Biotechnology and Fine Chemistry – Associate Laboratory, Faculty of Biotechnology, Porto, Portugal; 2Laboratory of Pharmacology and Experimental Therapeutics, Institute for Biomedical Imaging and Life Sciences (IBILI, Faculty of Medicine, and CNC.IBILI Consortium, University of Coimbra, Coimbra, Portugal; 3Department of Biochemistry, Faculty of Medicine, University of Porto, Porto, Portugal; 4Center for Health Technology and Services Research (CINTESIS, Porto, Portugal; 5Department of Pharmaceutical Sciences, Institute of Health Sciences-North, CESPU, Gandra, Portugal; 6“I3S” Instituto de Investigação e Inovação em Saúde, University of Porto, Porto, Portugal; 7INEB, Institute of Biomedical Engineering, University of Porto, Porto, Portugal Abstract: Rosmarinic acid (RA possesses several protective bioactivities that have attracted increasing interest by nutraceutical/pharmaceutical industries. Considering the reduced bioavailability after oral use, effective (and safe delivery systems are crucial to protect RA from gastrointestinal degradation. This study aims to characterize the safety profile of solid lipid nanoparticles produced with Witepsol and Carnauba waxes and loaded with RA, using in vitro and in vivo approaches, focused on genotoxicity and cytotoxicity assays, redox status markers, hematological and biochemical profile, liver and kidney function, gut bacterial microbiota, and fecal fatty acids composition. Free RA and sage extract, empty nanoparticles, or nanoparticles loaded with RA or sage extract (0.15 and 1.5 mg/mL were evaluated for cell (lymphocytes viability, necrosis and apoptosis, and antioxidant

  4. Feminismo(s e psicologia em Portugal

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    Azambuja, Mariana Porto Ruwer de

    2007-01-01

    Full Text Available Apesar da longa história em comum entre Brasil e Portugal, também existem muitas diferenças e, principalmente, muito desconhecimento. A proposta deste artigo é apresentar uma contextualização do modo como as questões de gênero têm sido tartadas Portugal e, a partir disto, estimular maiores laços de cooperação entre os dois países. Iniciamos com uma retomada da história do país e das reformas instauradas após o fim do regime fascista (1974, especialmente o surgimento da psicologia como campo científico e profissional marcado pelo paradigma positivista e, por muito tempo, alheio às transformações e questionamentos presentes em outros contextos. Da mesma forma, o percurso do movimento feminista e sua inserção no contexto acadêmico da psicologia foi marcado por avanços e entraves, os quais apresentamos a seguir. Por fim, tratamos das políticas públicas para a igualdade de oportunidades para as mulheres em Portugal

  5. Putting Portugal on the Map

    Directory of Open Access Journals (Sweden)

    João Ferrão

    2010-01-01

    Full Text Available This paper argues the need to “put Portugal on the map” in a double sense: in a prospective way, in order to place the country on the required map(s, something which entails strategic vision and capacity for action; and in an analytical way – to enable us to understand Portugal from the map(s it is part of, which presupposes a capacity to analyse and understand the current state of affairs. By drawing inspiration from the polymorphic vision on the spatialities of contemporary societies and economies defended by Jessop, Brenner and Jones (2008, we propose the creation of a unifying reference framework to “put Portugal on the map”, using a combination of five elements: territory as a geographic location; territory as a unit of reference of the nation-state; places; geographic scales; and networks. The polymorphic nature of the spatialities that characterize, or should characterize, Portugal’s place in the world reflects several, and even contradictory, ethical values, interests, preferences, and options. Accordingly, the supported polymorphic spatialities ought to stir up controversy based on knowledge and arguments that are solid from a theoretical and empirical stance, and should make explicit the objectives and values they are based on.

  6. Pension Systems in Europe. Case of Portugal

    Directory of Open Access Journals (Sweden)

    Jarosław Poteraj

    2009-03-01

    Full Text Available The article presents an insight into the old age pension system in Portugal. The author’s goal was to present both past and present solutions employed by the Portuguese’s pension system, in search for ideas worth consideration in international comparisons. In the summary, the author highlights as a particular Portuguese approach, on the background of other countries, the fact of using in Portugal definite part of VAT income for pension system financing.

  7. Effect of flaxseed supplementation and exercise training on lipid profile, oxidative stress and inflammation in rats with myocardial ischemia.

    Science.gov (United States)

    Nounou, Howaida A; Deif, Maha M; Shalaby, Manal A

    2012-10-05

    Flaxseed has recently gained attention in the area of cardiovascular disease primarily because of its rich contents of α-linolenic acid (ALA), lignans, and fiber. Although the benefits of exercise on any single risk factor are unquestionable, the effect of exercise on overall cardiovascular risk, when combined with other lifestyle modifications such as proper nutrition, can be dramatic.This study was carried out to evaluate the protective role of flaxseed and exercise on cardiac markers, lipids profile and inflammatory markers in isoproterenol (ISO)-induced myocardial ischemia in rats. The research was conducted on 40 male albino rats, divided into 4 groups (n=10): group I served as control, group II has acute myocardial ischemia induced by isoproterenol, groups III and IV have acute myocardial ischemia induced by isoproterenol pretreated with flaxseed supplementation orally for 6 weeks, additionally group IV practiced muscular exercise through swimming. Alterations of lipid profile, cardiac and inflammatory markers (Il-1β, PTX 3 and TNF- α) were observed in myocardial ischemia group. Flaxseed supplementation combined with exercise training showed significant increase of HDL and PON 1, on the other hand cardiac troponin, Il- 1β and TNF- α levels significantly decreased as compared to myocardial ischemic group. Receiver Operating Characteristics (ROC) analysis of cTnI, PTX 3, Il-1β and TNF- α revealed a satisfactory level of sensitivity and specificity. Regular exercise enhances the improvement in plasma lipoprotein levels and cardiovascular protection that results from flaxseed supplementation by mitigating the pathophysiology of atherosclerosis. Elevation of HDL, the antioxidant PON 1 and the cardioprotective marker PTX 3 emphasizes the protective effects of flaxseed and muscular exercise mutually against the harmful effects of acute myocardial ischemia.

  8. Effect of flaxseed supplementation and exercise training on lipid profile, oxidative stress and inflammation in rats with myocardial ischemia

    Directory of Open Access Journals (Sweden)

    Nounou Howaida A

    2012-10-01

    Full Text Available Abstract Background Flaxseed has recently gained attention in the area of cardiovascular disease primarily because of its rich contents of α-linolenic acid (ALA, lignans, and fiber. Although the benefits of exercise on any single risk factor are unquestionable, the effect of exercise on overall cardiovascular risk, when combined with other lifestyle modifications such as proper nutrition, can be dramatic. This study was carried out to evaluate the protective role of flaxseed and exercise on cardiac markers, lipids profile and inflammatory markers in isoproterenol (ISO-induced myocardial ischemia in rats. Methods The research was conducted on 40 male albino rats, divided into 4 groups (n=10: group I served as control, group II has acute myocardial ischemia induced by isoproterenol, groups III and IV have acute myocardial ischemia induced by isoproterenol pretreated with flaxseed supplementation orally for 6 weeks, additionally group IV practiced muscular exercise through swimming. Results Alterations of lipid profile, cardiac and inflammatory markers (Il-1β, PTX 3 and TNF- α were observed in myocardial ischemia group. Flaxseed supplementation combined with exercise training showed significant increase of HDL and PON 1, on the other hand cardiac troponin, Il- 1β and TNF- α levels significantly decreased as compared to myocardial ischemic group. Receiver Operating Characteristics (ROC analysis of cTnI, PTX 3, Il-1β and TNF- α revealed a satisfactory level of sensitivity and specificity. Conclusion Regular exercise enhances the improvement in plasma lipoprotein levels and cardiovascular protection that results from flaxseed supplementation by mitigating the pathophysiology of atherosclerosis. Elevation of HDL, the antioxidant PON 1 and the cardioprotective marker PTX 3 emphasizes the protective effects of flaxseed and muscular exercise mutually against the harmful effects of acute myocardial ischemia.

  9. HLA-DQA1 and HLA-DQB1 allele diversity and its extended haplotypes in Madeira Island (Portugal).

    Science.gov (United States)

    Spínola, H; Lemos, A; Couto, A R; Parreira, B; Soares, M; Dutra, I; Bruges-Armas, J; Brehm, A

    2017-02-01

    This study shows, for the first time, high-resolution allele frequencies of HLA-DQA1 loci in Madeira Island (Portugal) and allows us to better understand and refine present knowledge on DQB1 variation, with the identification of several alleles not previously reported in this population. Estimates on haplotype profile, involving HLA-A, HLA-B, HLA-DRB1, HLA-DQA1 and HLA-DQB1, are also reported. © 2016 John Wiley & Sons Ltd.

  10. Municipal solid waste disposal in Portugal

    International Nuclear Information System (INIS)

    Magrinho, Alexandre; Didelet, Filipe; Semiao, Viriato

    2006-01-01

    In recent years municipal solid waste (MSW) disposal has been one of the most important environmental problems for all of the Portuguese regions. The basic principles of MSW management in Portugal are: (1) prevention or reduction, (2) reuse, (3) recovery (e.g., recycling, incineration with heat recovery), and (4) polluter-pay principle. A brief history of legislative trends in waste management is provided herein as background for current waste management and recycling activities. The paper also presents and discusses the municipal solid waste management in Portugal and is based primarily on a national inquiry carried out in 2003 and directed to the MSW management entities. Additionally, the MSW responsibility and management structure in Portugal is presented, together with the present situation of production, collection, recycling, treatment and elimination of MSW. Results showed that 96% of MSW was collected mixed (4% was separately collected) and that 68% was disposed of in landfill, 21% was incinerated at waste-to-energy plants, 8% was treated at organic waste recovery plants and 3% was delivered to sorting. The average generation rate of MSW was 1.32 kg/capita/day

  11. Fronteira Portugal-Espanha e individualidade territorial

    Directory of Open Access Journals (Sweden)

    Carminda Cavaco

    1997-06-01

    Full Text Available PORTUGAL-SPAIN BORDER AREA AND ITS CREATIVE TENSION - The text evokes several nuances of the concept of the Portugal-Spain border: its shades of solidarity, complicity, opposition, agitation, confrontation and abandonment. At times, the border has been the zone of tension and separation, whereas at other periods in history, the border has been very permeable and there has been free exchange and mutual cooperation. The borders will be subjected to yet another interpretation as a new area emerges with the active participation of both Iberian countries in the European Union and the cooperative efforts initiated in the programs of INTERREG I and II

  12. [Demography and employment in Portugal].

    Science.gov (United States)

    Barata, O S

    1981-01-01

    The population of Portugal showed a period of slow growth between 1950-60; however, in the 1970s, the return of large numbers of former residents in African territories along with a reduction in emigration changed the trend so that the 1981 census showed a significant increase. The Portuguese economy, on the other hand, is in a state of crisis which has resulted in large numbers of unemployed. The growth of the population along with these hard times has made it more difficult to reduce the rate of unemployment. It is also more difficult for those leaving school to find jobs. The better educated generations are seeking jobs in industry and in other services that Portugal will find difficult to offer in sufficient numbers in the immediate future. At present, the Portuguese economy has a large component of agricultural labor. In any case, the means of economic and social intervention to fight unemployment have limited potential. Therefore, many of those unable to find jobs in Portugal will attempt to emigrate. Many Portuguese are already working in Germany, France, and in other Western European countries but migration today is much more difficult. In addition, these countries cannot be expected to recive many more migrant workers in the future. In fact, those better educated workers from Portugal will not be very interested in the low paying jobs which can be found more easily by foreign workers in Western Euorpe. Many will therefore attempt to find jobs in non-European countries. There has been a recent increase of migration to Canada and the US. A renewal of interest in jobs in Brazil and other South Amerian countries is also to be expected. There may also be a future increase in the number of experts, technicians, and other qualified personnel emigrating to Portuguese speaking African countries if there is adequate security and if these countries find the way to expand economic growth. (author's modified)

  13. Portugal: setting new goals for growth.

    Science.gov (United States)

    Cutler, B

    1987-11-01

    Portugal has entered a period of economic recovery spearheaded by Prime Minister Anibal Cavaco Silva. A slow but steady rise in the standard of living may finally offset the 0.9% annual growth in the country's population. Growth in the gross national product (GNP) reached 5% in 1987 and fixed capital investment increased 9.5% in 1986. Cavaco Silva's economic recovery program has included entry into the Common Market, foreign investment in industry, attention to the enormous public debt, and dismantling of the state-centered economy of the 1970s. Per capita GNP increased from US$743 in 1985 to $1970 in 1986 and unemployment had fallen to 8.5% by 1988. The prolongation of average life expectancy to 68 years for men and 75 years for women indicates a general improvement in the health and lifestyle of most Portuguese. By the year 2000, the population of Portugal is expected to reach 11.1 million, with the largest rates of growth occurring in the west and coastal areas. Half of the population falls into the 25-64-year age group, suggesting potential for economic growth and spending. A low rate of urbanization (30%) has complicated attempts to raise the level of technology in industry. Strong adherence to Catholicism is largely responsible for the exceptionally high marriage rate and low divorce rate in Portugal. The average birth rate was 14.5/1000 in 1987 and the average total fertility rate was 2.1. 34% of all births are to women 20-24 years old. The annual mortality rate is 9.6/1000, while infant mortality stands at 17.8/1000. A significant change occurring in Portugal in the current period is the rise of a new middle class.

  14. Introducción de las artes marciales asiáticas en Portugal = The introduction of asian martial arts in Portugal

    OpenAIRE

    Carlos Gutiérrez García; Vitor Alberto Rosa; Mikel Pérez Gutiérrez

    2013-01-01

    El presente estudio analiza la introducción del jujutsu en Portugal, sucedida a principios del siglo XX. Para su realización se ha consultado fundamentalmente prensa histórica portuguesa, tanto general como específica del ámbito deportivo. Los resultados obtenidos muestran que la introducción del jujutsu en Portugal se produjo fundamentalmente a través del mundo del espectáculo, mediante actuaciones de expertos japoneses. Las notables diferencias técnicas y corporales entre estos luchadores j...

  15. Evaluating fishermen's conservation attitudes and local ecological knowledge of the European sardine (Sardina pilchardus), Peniche, Portugal.

    Science.gov (United States)

    Braga, Heitor O; Azeiteiro, Ulisses M; Oliveira, Henrique M F; Pardal, Miguel A

    2017-05-05

    European sardines are an important fishing resource in the North Atlantic. Recognized for its great commercial and economic value in southern Europe, this resource currently has low stock indices. From this perspective, fishers' local ecological knowledge (LEK) is appreciated as an auxiliary tool in the management of sardines in this region. Our goal is to evaluate the LEK and attitudes towards the conservation of Sardina pilchardus in the typical fishing village of Peniche, Portugal. From June to September 2016, we carried out 87 semi-structured interviews. The four main points of the interviews were interviewee profile, fishing structure, fishermen's LEK and attitudes towards sardine conservation. The interviews were qualitatively and quantitatively analyzed using a 3-point Likert scale. An LEK index and an attitude index were generated. Comparison analyses and correlations were made between the indices and variables of the interviewee profile and the fishing structure. The mean LEK index was 0.55 and was classified as moderate. The attitudes index in relation to conservation was 0.76 and was classified as positive. This index had a positive and significant correlation with the LEK index and a significant negative correlation with the fishermen's age. When the LEK index was compared with the educational level, significant differences were observed only between class A and class C. The result showed that the differences in the attitudes index were statistically significant when the three educational classes were compared. The fishermen of Peniche in Portugal present moderate informal knowledge about the biology and ecology of sardines. Attitudes towards conservation were predominantly positive. Fishermen with greater LEK, with a higher educational level and at a younger age presented more positive attitudes in relation to environmental conservation issues in the present case of the sardine population. The LEK is not necessarily related to the educational level of

  16. Spain and Portugal facing Euratom. Some considerations in the access of Spain and Portugal to Euratom

    International Nuclear Information System (INIS)

    Corretjer, L.; Lopez Rodriguez, M.

    1985-01-01

    The access of Spain and Portugal to the European Community of Atomic Energy (EURATOM) will give rise to significative consequences and it is a subject which must be thoroughly considered as to its implications regarding the present state of nuclear development in both countries and with regard to their reciprocal relations in nuclear energy matters. To determine such consequences and implications it is necessary, first of all, to analyze what EURATOM is and how it acts, in addition to consider the situation of each of its Member States as to the utilization of nuclear energy. As well, it is necessary to explain the evolution and the present situation of nuclear development in Spain and in Portugal and their mutual relations in this field. In pursuit of such analysis we may determine the possible consequences of their access; this is made bearing in mind each of the aspects in which EURATOM acts, according to the Treaty and the ''acquis communitaire'', and dividing them into common consequences and individual ones for both countries. The whole exposition, which was studied and carried out from an exclusively technical point of view, has a result the deduction of the joint possibilities offered to Spain and Portugal to make use of EURATOM's availabilities and of the joint actions which both countries may achieve to benefit as much as possible from their access to EURATOM. (author)

  17. Performance indicators for clinical practice management in primary care in Portugal: consensus from a Delphi study.

    Science.gov (United States)

    Basto-Pereira, Miguel; Furtado, Sara Isabel Félix; Silva, Ricardo Jorge Pereira; Fachado González, Francisco; Vara Fernandes, Tito Manuel; Correia de Sousa, Jaime; Yaphe, John

    2015-03-01

    Performance indicators assessing the quality of medical care and linked to pay for performance may cause disagreement. Portuguese indicators included in recent health care reform are controversial. To obtain consensus from opinion leaders in family medicine regarding the performance indicators for practice management used in the evaluation of Family Health Units in Portugal. Eighty-nine specialists in primary care were invited to answer the following question in an online Delphi study: 'Which performance indicators should be assessed regarding the organization and management of clinical practice in primary care in Portugal?' A Likert scale was used to evaluate validity, reliability, feasibility and sensitivity to change. Twenty-seven experts participated in the second round and achieved a high degree of consensus. Eight categories were created for analysis. The experts suggested the use of existing indicators as well as new indicators. Thirty-nine indicators suggested by the experts are currently in use in Portugal. The assessment of the number of clinical acts performed, the number of administrative acts, and evaluation of the clinical demographic profile achieved a high degree of consensus. The expert panel suggested fifty new indicators. Five categories of these new indicators had a high degree of consensus, and three categories had a low degree of consensus. The expert panel recommended that performance indicators of practice management should first assess the quantity of clinical and administrative activities undertaken. These indicators must take into account the human and financial resources available to the clinic and its demographic context.

  18. Hierarchy formation and hormonal profiles in Australoherus facetus, an invasive freshwater fish in Portugal.

    Directory of Open Access Journals (Sweden)

    Flávia Baduy

    2015-11-01

    Full Text Available Australoheros facetus is a highly social neotropical cichlid that is invasive in the Guadiana and Odelouca basins (Southern Portugal. Phenotypic plasticity is believed to be a key component for invasive success. However, its biology remains largely unknown. In this research we aimed to characterize the behaviour and hormone profiles (Testosterone (T, Estradiol (E, 11-keto-testosterone (11KT and Cortisol throughout the formation of stable social groups, a crucial step in the life-history of A. facetus. Fifteen social groups (n=4-6 size matched individuals per group were observed and filmed until stable hierarchies were formed (7 days at different periods of the year. An ethogram was established and a dominance index (DI=wins/ total interactions was used to quantify social dominance. Blood samples were taken from all fish at the beginning and end of the experiment. After the trial period, the animals were sacrificed and the gonads inspected for sex determination. A pair breeding strategy with territorial behaviour was found, and territorial status was attributed to fish that formed a breeding couple and defended an arena. A positive correlation was found between dominance and size for both sexes (length: females R=0.63, males R=0.74; Weight: females R=0.79; males R=0.69; p<0.05. There were no differences between individuals in the initial levels of all hormones, but while T and E showed no evident pattern, final 11KT was higher in territorial males (territorial=2.30ng/mL, non-territorial=1.11ng/mL, p<0.05. Final cortisol were higher in non-territorial males (territorial=96.91ng/mL, non-territorial=163.3ng/mL, p<0.05 and negatively correlated with dominance (R=-0.47, p<0.05. These results suggest that size is the main driver for social dominance and that high social status lowers stress in all fish and increases 11KT secretion in males. Further analysis are in progress to understand the complex reproductive processes and the interspecific

  19. Geology and religion in Portugal

    Science.gov (United States)

    Carneiro, Ana; Simoes, Ana; Diogo, Maria Paula; Mota, Teresa Salomé

    2013-01-01

    This paper addresses the relationship between geology and religion in Portugal by focusing on three case studies of naturalists who produced original research and lived in different historical periods, from the eighteenth to the twentieth century. Whereas in non-peripheral European countries religious themes and even controversies between science and religion were dealt with by scientists and discussed in scientific communities, in Portugal the absence of a debate between science and religion within scientific and intellectual circles is particularly striking. From the historiographic point of view, in a country such as Portugal, where Roman Catholicism is part of the religious and cultural tradition, the influence of religion in all aspects of life has been either taken for granted by those less familiar with the national context or dismissed by local intellectuals, who do not see it as relevant to science. The situation is more complex than these dichotomies, rendering the study of this question particularly appealing from the historiographic point of view, geology being by its very nature a well-suited point from which to approach the theme. We argue that there is a long tradition of independence between science and religion, agnosticism and even atheism among local elites. Especially from the eighteenth century onwards, they are usually portrayed as enlightened minds who struggled against religious and political obscurantism. Religion—or, to be more precise, the Roman Catholic Church and its institutions—was usually identified with backwardness, whereas science was seen as the path to progress; consequently men of science usually dissociated their scientific production from religious belief.

  20. First autochthone case of sporotrichosis by Sporothrix globosa in Portugal.

    Science.gov (United States)

    de Oliveira, Manoel Marques Evangelista; Veríssimo, Cristina; Sabino, Raquel; Aranha, João; Zancopé-Oliveira, Rosely Maria; Sampaio, Paula; Pais, Célia

    2014-04-01

    In this study, we characterize the first autochthone case of human sporotrichosis reported in Lisbon, Portugal. Phenotypic and genotypic characterization revealed that the infection was caused by Sporothrix globosa. We conclude that sporotrichosis may be underdiagnosed particularly in Southern Europe and suggest Portugal as an emerging area for this fungal infection. © 2014 Elsevier Inc. All rights reserved.

  1. Kolmas vaatus Euroopa võlakriisis - Portugal. Oht Portugali mainel / Sirje Rank

    Index Scriptorium Estoniae

    Rank, Sirje, 1966-

    2011-01-01

    Portugal kavatseb läbi viia riigivõlakirjade emissiooni, samas müüvad teisedki riigid lähiajal võlakirju, mille riskiaste on väiksem. Portugal eitab väidet, nagu oleks Saksamaa ja Prantsusmaa survestanud teda Euroopa kriisifondist abi küsima

  2. PSYCHOSOCIAL REHABILITATION IN ASSISTED HOUSING IN BRAZIL AND PORTUGAL

    Directory of Open Access Journals (Sweden)

    Antonio José de Almeida Filho

    2016-01-01

    Full Text Available El objetivo de esta investigación es analizar cómo las Casas Terapéuticas para los usuarios con trastornos mentales en los municipios de Miranda do Corvo-Portugal y Volta Redonda-Brasil contribuyen a la rehabilitación psicosocial de las personas con sufrimiento mental. Estudio de perspectiva histórica, cuyas fuentes históricas fueron leyes, resoluciones e informes oficiales y declaraciones de enfermeras, psicólogos y trabajadores sociales. Se encontró que en ambos municipios la intención es la desinstitucionalización de las personas con sufrimiento mental, en Miranda do Corvo-Portugal la gestión financiera y administrativa es responsabilidad de una fundación y, en Volta Redonda-Brasil esta gestión es auspiciada por el ejecutivo municipal, además de observar en Miranda del Corvo-Portugal la adopción de medidas disciplinarias en función de exceso de los usuarios. Se concluye que la crisis económica en Portugal ha interferido con la política de expansión de las Casas Terapéuticas en cuanto al número de usuarios que no permite la intervención más individualizada.

  3. O Ecoturismo em Portugal: caraterização da oferta centrada nos Agentes de Animação Turística

    Directory of Open Access Journals (Sweden)

    Bruna Filipa Miranda Cordeiro

    2017-01-01

    Full Text Available The growing ecotourism market, result of a paradigm shift, with important changes of the tourist profile, who selects their holiday destination based on criteria and environmental and social motivations. Faced with this growing demand, there are several companies that have seen this tourist segment as a busi‑ ness opportunity. Based on this assumption and exploratory analysis of tourist animation agents in Portugal (Cordeiro, Alves and Carvalho, 2015, in this article we intend to deepen the knowledge about the market of ecotourism offer, through an online survey for these agents. In addition to other relevant data, in the uni‑ verse of 28 companies identified, 17 participated in the survey, and of these 94.1% claim to sell ecotourism segment, what, not only validates the study referred above, as suggests, also, in later stage, an analysis in search of ecotourists in Portugal.

  4. Nurses in advanced roles: a review of acceptability in Portugal Las enfermeras de competencias avanzadas: una revisión de aceptación en Portugal Enfermeiros em funções avançadas: uma análise da aceitação em Portugal

    Directory of Open Access Journals (Sweden)

    James Buchan

    2013-02-01

    Full Text Available OBJECTIVE: This paper focuses on the policy context for the deployment of nurses in advanced roles, with particular reference to Portugal. The health sector in Portugal, as in all countries, is labour intensive, and the scope to utilise nurses in more advanced roles is currently being debated. METHODS: Mixed methods were used: an analysis of international data on the nursing workforce; an analysis of documents and media articles; interviews with key-informants; an online survey of managers, and a technical workshop with key-informants. CONCLUSIONS: The limited evidence base on nurses in advanced roles in Portugal is a constraint on progress, but it is not an excuse for inaction. Further research in Portugal on health professionals in innovative roles would assist in informing policy direction. There is the need to move forward with a fully informed policy dialogue, taking account of the current political, economic and health service realities of Portugal.OBJETIVO: Este estudio se focaliza en el contexto político del desarrollo de competencias avanzadas de enfermería, con énfasis en el caso portugués. El sector de la salud en Portugal, como en todos los países, es intensivo en mano de obra, y la posibilidad de utilizar enfermeros en funciones más avanzadas está actualmente en debate. MÉTODOS: Fue utilizado una aproximación mixta: análisis de datos internacionales sobre la fuerza de trabajo de enfermería; análisis de documentos y noticias; entrevistas con informadores clave; un cuestionario online y una oficina técnica con informadores clave. CONCLUSIONES: La limitada base de evidencia sobre la extensión de competencias de los enfermeros en Portugal es un obstáculo para el progreso pero no es una excusa para la inacción. Investigación adicional sobre profesionales de la salud en papeles innovadores podría ayudar a informar y direccionar la decisión política. Es necesario avanzar con un diálogo político plenamente informado

  5. A comparative analysis of tourism destination demand in Portugal

    OpenAIRE

    Serra, Jaime; Correia, Antónia; Rodrigues, Paulo M.M.

    2014-01-01

    Tourism has experienced different levels of development in the different regions of Portugal.To frame this development, in this paper dynamic panel data models were estimated with the objective of explaining the evolution of international overnight stays in each region.Secondary data from 2000 to 2011 was used.The analysis includes the main tourism source markets for Portugal, such as the United Kingdom, Germany,the Netherlands, Ireland, France and Spain. The tourism literature suggests that,...

  6. A country-wide probability sample of public attitudes toward stuttering in Portugal.

    Science.gov (United States)

    Valente, Ana Rita S; St Louis, Kenneth O; Leahy, Margaret; Hall, Andreia; Jesus, Luis M T

    2017-06-01

    Negative public attitudes toward stuttering have been widely reported, although differences among countries and regions exist. Clear reasons for these differences remain obscure. Published research is unavailable on public attitudes toward stuttering in Portugal as well as a representative sample that explores stuttering attitudes in an entire country. This study sought to (a) determine the feasibility of a country-wide probability sampling scheme to measure public stuttering attitudes in Portugal using a standard instrument (the Public Opinion Survey of Human Attributes-Stuttering [POSHA-S]) and (b) identify demographic variables that predict Portuguese attitudes. The POSHA-S was translated to European Portuguese through a five-step process. Thereafter, a local administrative office-based, three-stage, cluster, probability sampling scheme was carried out to obtain 311 adult respondents who filled out the questionnaire. The Portuguese population held stuttering attitudes that were generally within the average range of those observed from numerous previous POSHA-S samples. Demographic variables that predicted more versus less positive stuttering attitudes were respondents' age, region of the country, years of school completed, working situation, and number of languages spoken. Non-predicting variables were respondents' sex, marital status, and parental status. A local administrative office-based, probability sampling scheme generated a respondent profile similar to census data and indicated that Portuguese attitudes are generally typical. Copyright © 2017 Elsevier Inc. All rights reserved.

  7. Portugal's Secondary School Modernisation Programme

    Science.gov (United States)

    Heitor, Teresa V.; Freire da Silva, Jose M. R.

    2009-01-01

    The aim of the Secondary School Modernisation Programme, being implemented in Portugal by "Parque Escolar, EPE", is based on the pursuit of quality and makes Portuguese education a potential international benchmark. This paper discusses the strategies adopted to reorganise school spaces. It describes the conceptual model and highlights…

  8. Multivariate statistical analysis of wildfires in Portugal

    Science.gov (United States)

    Costa, Ricardo; Caramelo, Liliana; Pereira, Mário

    2013-04-01

    Several studies demonstrate that wildfires in Portugal present high temporal and spatial variability as well as cluster behavior (Pereira et al., 2005, 2011). This study aims to contribute to the characterization of the fire regime in Portugal with the multivariate statistical analysis of the time series of number of fires and area burned in Portugal during the 1980 - 2009 period. The data used in the analysis is an extended version of the Rural Fire Portuguese Database (PRFD) (Pereira et al, 2011), provided by the National Forest Authority (Autoridade Florestal Nacional, AFN), the Portuguese Forest Service, which includes information for more than 500,000 fire records. There are many multiple advanced techniques for examining the relationships among multiple time series at the same time (e.g., canonical correlation analysis, principal components analysis, factor analysis, path analysis, multiple analyses of variance, clustering systems). This study compares and discusses the results obtained with these different techniques. Pereira, M.G., Trigo, R.M., DaCamara, C.C., Pereira, J.M.C., Leite, S.M., 2005: "Synoptic patterns associated with large summer forest fires in Portugal". Agricultural and Forest Meteorology. 129, 11-25. Pereira, M. G., Malamud, B. D., Trigo, R. M., and Alves, P. I.: The history and characteristics of the 1980-2005 Portuguese rural fire database, Nat. Hazards Earth Syst. Sci., 11, 3343-3358, doi:10.5194/nhess-11-3343-2011, 2011 This work is supported by European Union Funds (FEDER/COMPETE - Operational Competitiveness Programme) and by national funds (FCT - Portuguese Foundation for Science and Technology) under the project FCOMP-01-0124-FEDER-022692, the project FLAIR (PTDC/AAC-AMB/104702/2008) and the EU 7th Framework Program through FUME (contract number 243888).

  9. Occupational radiation doses in Portugal from 1994 to 1998

    International Nuclear Information System (INIS)

    Alves, J.G.; Martins, M.B.; Amaral, E.M.

    2000-01-01

    This work reports on the occupational radiation doses for external radiation received in 1994-1998 by the radiation workers monitored by the Radiological Protection and Nuclear Safety Department (DPRSN) in Portugal. Individual monitoring for external radiation is carried out in Portugal by DPRSN since the 60s, and the workers are monitored on a monthly or quarterly bases. In 1995 DPRSN monitored approximately 8000 people and was the only laboratory carrying out this sort of activity in Portugal. In 1998 the number of monitored people increased to nearly 8500 from 860 facilities, which leads us to state that the results shown in this work are well representative of the universe of radiation workers in Portugal. Until 1996, the dose measurement procedure was based only on film dosimetry and the results reported for the 1994-1995 period were obtained with this methodology. Since 1996, thermoluminescent dosimetry (TLD) was gradually introduced and since then an effort has been made to transfer the monitored workers from film to TLD. In 1998, both film and TLD dosimetry systems were running simultaneously, with average numbers of 4500 workers monitored with film dosimetry, while 4000 were monitored with TLD. The data presented from 1996 to 1998 were obtained with both methodologies. This work reports the annual mean effective doses received from external radiation, for the monitored and exposed workers in the different fields of activity, namely, industry, research laboratories, health and mining. The distribution of the annual effective dose by dose intervals is also reported. The collective annual dose by field of activity is estimated and the contribution to the total annual collective dose is determined. The collective dose estimates for the period 1994 to 1998 demonstrated that the health sector is the most representative exposed group in Portugal. (author)

  10. IDENTIFIKASI WASTE PADA WHOLE STREAM PERUSAHAAN ROKOK DI PT.X16

    Directory of Open Access Journals (Sweden)

    Rakhmawati Rakhmawati

    2016-11-01

    Full Text Available Identify to be done by using method of lean manufacturing. This research aimed at identify waste and formulate effort reduction of waste production process smoke in PT.X. The data were collected from manufacturer records, study to determine processing time, as well as interview and quisioners which were distributed to workers in each department. Big picture mapping and value stream mapping tools (VALSAT were then utilised to process the data.Result of from research got that during once production process can reduce from 152.59 minute become 149.59 time and minute every order 26 day become 19 day. From result of waste workshop known that type extravagance of cause the happening of production process time depth ( 3 highest is defect, waiting time and excessive transportation, so that appliance (tool matching with the extravagance type is mapping filter quality with successive wight 96,6 : 55,86 : and 23,32.According to the result found also cause of extravagance for example, to the number of time used for the activity of inspection between aktifitas so that cause production process time become Ilama, existence of distance which among tobacco warehouse with process of perajangan resulting the happening of movement of bolak return worker so that add production process time become llama. One of the ways to improve it is by applying pull system (Kanban.

  11. Developmental Dyslexia: Perspectives on Teacher Training and Learning Disabilities in Portugal

    Science.gov (United States)

    Carvalhais, Lenia; da Silva, Carlos Fernandes

    2010-01-01

    The focus of this study was to explore primary teachers' attitudes and perceptions toward their training experiences, instructional practices, and supports received in their schools toward working with students with dyslexia in Portugal. Primary school teachers from the centre of Portugal, working with children between the first and fourth grades,…

  12. Site-conditions map for Portugal based on VS measurements: methodology and final model

    Science.gov (United States)

    Vilanova, Susana; Narciso, João; Carvalho, João; Lopes, Isabel; Quinta Ferreira, Mario; Moura, Rui; Borges, José; Nemser, Eliza; Pinto, carlos

    2017-04-01

    In this paper we present a statistically significant site-condition model for Portugal based on shear-wave velocity (VS) data and surface geology. We also evaluate the performance of commonly used Vs30 proxies based on exogenous data and analyze the implications of using those proxies for calculating site amplification in seismic hazard assessment. The dataset contains 161 Vs profiles acquired in Portugal in the context of research projects, technical reports, academic thesis and academic papers. The methodologies involved in characterizing the Vs structure at the sites in the database include seismic refraction, multichannel analysis of seismic waves and refraction microtremor. Invasive measurements were performed in selected locations in order to compare the Vs profiles obtained from both invasive and non-invasive techniques. In general there was good agreement in the subsurface structure of Vs30 obtained from the different methodologies. The database flat-file includes information on Vs30, surface geology at 1:50.000 and 1:500.000 scales, elevation and topographic slope and based on SRTM30 topographic dataset. The procedure used to develop the site-conditions map is based on a three-step process that includes defining a preliminary set of geological units based on the literature, performing statistical tests to assess whether or not the differences in the distributions of Vs30 are statistically significant, and merging of the geological units accordingly. The dataset was, to some extent, affected by clustering and/or preferential sampling and therefore a declustering algorithm was applied. The final model includes three geological units: 1) Igneous, metamorphic and old (Paleogene and Mesozoic) sedimentary rocks; 2) Neogene and Pleistocene formations, and 3) Holocene formations. The evaluation of proxies indicates that although geological analogues and topographic slope are in general unbiased, the latter shows significant bias for particular geological units and

  13. Students' Perceptions of Assessment: A Comparative Analysis between Portugal and Sweden

    Science.gov (United States)

    Pereira, Diana; Niklasson, Laila; Flores, Maria Assunção

    2017-01-01

    This paper aims at investigating students' perceptions about assessment, especially the ways in which it is put into practice. Data were collected through questionnaires in different programmes in Portugal and Sweden. In total, 173 students from Portugal and 72 from Sweden participated in the study. Findings showed that students had similar ideas…

  14. Health professionals moving to... and from Portugal.

    Science.gov (United States)

    Ribeiro, Joana Sousa; Conceição, Claudia; Pereira, Joel; Leone, Cláudia; Mendonça, Pedro; Temido, Marta; Vieira, Carlota Pacheco; Dussault, Gilles

    2014-02-01

    The mobility of health professionals in the European Union is a phenomenon which policy-makers must take into account to provide the conditions to adjust for demand and supply of health services. This paper presents the case of Portugal, a country which at the same time imports and exports health workers. Since the early 1990s Portugal became a destination country receiving foreign health care professionals. This situation is now changing with the current economic situation as fewer immigrants come and more Portuguese emigrate. Foreigners coming to Portugal do so in part for similar reasons that bring Portuguese to want to emigrate, mainly the search for better work conditions and professional development opportunities. The emigration of Portuguese health professionals is also stimulated by the difficulty for recently graduated nurses, dentists and diagnostic and therapeutic technicians to find employment, low salaries in the public and private sectors, heavy workloads, remuneration not related to performance and poor career prospects. The paradoxes described in this study illustrate the consequences of the absence of a policy for the health professions. Strategies based on evidence, and on an integrated information system that captures the dynamic evolution of the workforce in health are not only necessary but also a good investment. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  15. Development and evaluation of targeting ligands surface modified paclitaxel nanocrystals

    Energy Technology Data Exchange (ETDEWEB)

    Sohn, Jeong Sun [Division of Undeclared Majors, Chosun University, Gwangju 501-759 (Korea, Republic of); Yoon, Doo-Soo; Sohn, Jun Youn [Department of Bioenvironmental & Chemical Engineering, Chosun College of Science & Technology, Gwangju 501-744 (Korea, Republic of); Park, Jeong-Sook, E-mail: eicosa@cnu.ac.kr [College of Pharmacy and Institute of Drug Research and Development, Chungnam National University, 99 Daehak-ro, Yuseong-gu, Daejeon 34134 (Korea, Republic of); Choi, Jin-Seok, E-mail: c34281@gmail.com [College of Pharmacy and Institute of Drug Research and Development, Chungnam National University, 99 Daehak-ro, Yuseong-gu, Daejeon 34134 (Korea, Republic of)

    2017-03-01

    To overcome the toxicity of excipient or blank nanoparticles for drug delivery nano-system, the surface modified paclitaxel nanocrystals (PTX-NC) have been developed. PTX-NCs were prepared by nano-precipitation method. The surface of PTX-NCs were modified by grafting with apo-transferrin (Tf) or hyaluronic acid (HA). The physical properties of PTX-NCs were evaluated by field emission scanning electron microscope (FE-SEM), zeta-sizer, zeta-potential, differential scanning calorimetry (DSC) and Fourier transform infrared (FT-IR) spectrometry. In vitro drug release study was performed in phosphate buffered saline (PBS) with or without 0.5% (w/v) Tween 80 for 24 h. Cellular uptake was studied at time intervals of 0.5, 1, and 2 h in MCF-7 cells, and cell growth inhibition study was performed for 24 h using MCF-7 cells (cancer cells), and HaCaT cells (normal cells). Three different types of PTX-NCs with a mean size of 236.0 ± 100.6 nm (PTX-NC), 302.0 ± 152.0 nm (Tf-PTX-NC) and 339 ± 180.6 nm (HA-PTX-NC) were successfully prepared. The drug release profiles showed 29.1%/6.9% (PTX (pure)), 40.7%/23.9% (PTX-NC), 50.5%/25.1% (Tf-PTX-NC) and 46.8/24.8% (HA-PTX-NC) in PBS with/without 0.5% (w/v) Tween 80 for 24 h, respectively. As per the results, the drug release of PTX-NCs showed the faster release as compared to that of PTX (pure). Surface modified PTX-NCs exhibited higher values for cell permeability than unmodified PTX-NC in the cellular uptake study. Surface modified PTX-NCs inhibited the cell growth approximately to 60% in MCF-7 cells, however effect of surface modified PTX-NCs on normal cell line was lower than the PTX-NC and PTX (pure). In conclusion, biological macromolecules (Tf or HA) surface modified PTX-NC enhanced the cellular uptake and the cell growth inhibition. - Highlights: • Surface modified PTX-NCs with HA and Tf are successfully prepared by adsorption method. • Enhanced cellular uptake of modified PTX-NCs compared to unmodified PTX-NC • Improved

  16. [Scientific Research Policy for Health in Portugal: II - Facts and Suggestions].

    Science.gov (United States)

    Guerreiro, Cátia Sá; Hartz, Zulmira; Sambo, Luís; Conceição, Cláudia; Dussault, Gilles; Russo, Giuliano; Viveiros, Miguel; Silveira, Henrique; Pita Barros, Pedro; Ferrinho, Paulo

    2017-03-31

    After more than 40 years of democracy and 30 years of European integration, Portugal has bridged the research gap it had previously. However, when compared to global and European research policies, Portugal still has a long way go regarding investment in research and development. Health Research in Portugal has been managed by the Fundação para a Ciência e Tecnologia and the National Health Institute Doctor Ricardo Jorge, and it has not been a political priority, emphasized by the absence of a national scientific research plan for health, resulting in a weak coordination of actors in the field. The strategic guidelines of the 2004 - 2010 National Health Plan are what comes closest to a health research policy, but these were not implemented by the institutions responsible for scientific research for the health sector. Trusting that adopting a strategy of incentives to stimulate health research is an added-value for the Portuguese health system, the authors present five strategic proposals for research in health in Portugal.

  17. Census Model Transition: Contributions to its Implementation in Portugal

    Directory of Open Access Journals (Sweden)

    Dias Carlos A.

    2016-03-01

    Full Text Available Given the high cost and complexity of traditional censuses, some countries have started to change the census process. Following this trend, Portugal is also evaluating a new census model as an alternative to an exhaustive collection of all statistical units. The main motivations for the implementation of this census model transition in Portugal are related to the decrease in statistical burden on citizens, improvements in the frequency of outputs, and the reduction of collection costs associated with census operations. This article seeks to systematise and critically review all alternatives to the traditional census methodologies, presenting their advantages and disadvantages and the countries that use them. As a result of the comparison, we conclude that the methods that best meet these objectives are those that use administrative data, either in whole or in part. We also present and discuss the results of an inventory and evaluation of administrative registers in Portugal with the potential to produce statistical census information.

  18. Quality of environmental impact statements in Portugal and Spain

    International Nuclear Information System (INIS)

    Canelas, Leonel; Almansa, P.; Merchan, M.; Cifuentes, Pedro

    2005-01-01

    One of the key steps of the Environmental Impact Assessment Process, defined by Directive 337/85 'on the assessment of the effects of certain public and private projects' is the preparation of the Environmental Impact Statement (EIS) of a Project. The quality of the EIS is of great importance to properly inform the public and the decision makers about the significant environmental effects of the project. Using the 'Guidance on EIA-EIS Review' 2001 report, produced with the support of the European Commission, this paper analyses the overall quality of 46 recently elaborated EIS from Portugal and Spain (1998-2003). It also analyses the quality of the various chapters of the EIS and the Non-Technical Summary. A comparison is made between the quality of the EIS from Portugal and from Spain. The results for Portugal are also compared with those of other European countries (Ireland and United Kingdom) in similar periods. Finally it presents overall conclusions and suggestions for improvement

  19. Highly active carbon supported ternary PdSnPtx (x=0.1-0.7) catalysts for ethanol electro-oxidation in alkaline and acid media.

    Science.gov (United States)

    Wang, Xiaoguang; Zhu, Fuchun; He, Yongwei; Wang, Mei; Zhang, Zhonghua; Ma, Zizai; Li, Ruixue

    2016-04-15

    A series of trimetallic PdSnPtx (x=0.1-0.7)/C catalysts with varied Pt content have been synthesized by co-reduction method using NaBH4 as a reducing agent. These catalysts were characterized using X-ray diffraction (XRD), transmission electron microscopy (TEM), high resolution transmission electron microscopy (HRTEM), energy dispersive X-ray spectroscopy (EDX), X-ray photoelectron spectroscopy (XPS), cyclic voltammetry (CV) and chronoamperometry (CA). The electrochemical results show that, after adding a minor amount of Pt dopant, the resultant PdSnPtx/C demonstrated more superior catalytic performance toward ethanol oxidation as compared with that of mono-/bi-metallic Pd/C or PdSn/C in alkaline solution and the PdSnPt0.2/C with optimal molar ratio reached the best. In acid solution, the PdSnPt0.2/C also depicted a superior catalytic activity relative to the commercial Pt/C catalyst. The possible enhanced synergistic effect between Pd, Sn/Sn(O) and Pt in an alloyed state should be responsible for the as-revealed superior ethanol electro-oxidation performance based upon the beneficial electronic effect and bi-functional mechanism. It implies the trimetallic PdSnPt0.2/C with a low Pt content has a promising prospect as anodic electrocatalyst in fields of alkali- and acid-type direct ethanol fuel cells. Copyright © 2016 Elsevier Inc. All rights reserved.

  20. The impact of winter cold weather on acute myocardial infarctions in Portugal

    International Nuclear Information System (INIS)

    Vasconcelos, João; Freire, Elisabete; Almendra, Ricardo

    2013-01-01

    Mortality due to cardiovascular diseases shows a seasonal trend that can be associated with cold weather. Portugal is the European country with the highest excess winter mortality, but nevertheless, the relationship between cold weather and health is yet to be assessed. The main aim of this study is to identify the contribution of cold weather to cardiovascular diseases within Portugal. Poisson regression analysis based on generalized additive models was applied to estimate the influence of a human-biometeorological index (PET) on daily hospitalizations for myocardial infarction. The main results revealed a negative effect of cold weather on acute myocardial infarctions in Portugal. For every degree fall in PET during winter, there was an increase of up to 2.2% (95% CI = 0.9%; 3.3%) in daily hospital admissions. This paper shows the need for public policies that will help minimize or, indeed, prevent exposure to cold. -- Highlights: ► We model the relationship between daily hospitalizations due to myocardial infarctions and cold weather in Portugal. ► We use Physiological Equivalent temperature (PET) as main explanatory variable. ► We adjust the models to confounding factors such as influenza and air pollution. ► Daily hospitalizations increased up to 2.2% per degree fall of PET during winter. ► Exposure to cold weather has a negative impact on human health in Portugal. -- There is an increase of up to 2.2% in daily hospitalizations due to acute myocardial infarctions per degree fall of thermal index during the winter months in Portugal

  1. Hydro-geomorphologic events in Portugal and its association with Circulation weather types

    Science.gov (United States)

    Pereira, Susana; Ramos, Alexandre M.; Rebelo, Luís; Trigo, Ricardo M.; Zêzere, José L.

    2017-04-01

    Floods and landslides correspond to the most hazardous weather driven natural disasters in Portugal. A recent improvement on their characterization has been achieved with the gathering of basic information on past floods and landslides that caused social consequences in Portugal for the period 1865-2015 through the DISASTER database (Zêzere et al., 2014). This database was built under the assumption that strong social impacts of floods and landslides are sufficient relevant to be reported consistently by national and regional newspapers. The DISASTER database contains detailed information on the location, date of occurrence and social impacts (fatalities, injuries, missing people, evacuated and homeless people) of each individual hydro-geomorphologic case (1677 flood cases and 292 landslide cases). These hydro-geomorphologic disaster cases are grouped in a restrict number of DISASTER events that were selected according to the following criteria: a set of at least 3 DISASTER cases sharing the same trigger in time (with no more than 3 days without cases), which have a widespread spatial extension related to the triggering mechanism and a certain magnitude. In total, the DISASTER database includes 134 events (3.7 average days of duration) that generated high social impacts in Portugal (962 fatalities and 40878 homeless people). Each DISASTER event was characterized with the following attributes: hydro-geomorphologic event type (e.g landslides, floods, flash floods, urban floods); date of occurrence (year, month and days); duration in days; spatial location in GIS; number of fatalities, injured, evacuated and homeless people; and weather type responsible for triggering the event. The atmospheric forcing at different time scales is the main trigger for the hydro-meteorological DISASTER events occurred in Portugal. In this regard there is an urge for a more systematic assessment of the weather types associated to flood and landslide damaging events to correctly

  2. The Time Profile of Pentraxin 3 in Patients with Acute ST-Elevation Myocardial Infarction and Stable Angina Pectoris Undergoing Percutaneous Coronary Intervention

    Directory of Open Access Journals (Sweden)

    Ragnhild Helseth

    2014-01-01

    Full Text Available Background. High levels of Pentraxin 3 (PTX3 are reported in acute myocardial infarction (AMI. Aim. To investigate circulating levels and gene expression of PTX3 in patients with AMI and stable angina pectoris (AP undergoing PCI. Methods. Ten patients with AP and 20 patients with AMI were included. Blood samples were drawn before PCI in the AP group and after 3 and 12 hours and days 1, 3, 5, 7, and 14 in both groups. Results. Circulating PTX3 levels were higher in AMI compared to AP at 3 and 12 hours (P<0.001 and P=0.003. Within the AMI group, reduction from 3 hours to all later time points was observed (all P≤0.001. Within the AP group, increase from baseline to 3 hours (P=0.022, followed by reductions thereafter (all P<0.05, was observed. PTX3 mRNA increased in the AMI group from 3 hours to days 7 and 14 in a relative manner of 62% and 73%, while a relative reduction from baseline to 3 and 12 hours of 29% and 37% was seen in the AP group. Conclusion. High circulating PTX3 levels shortly after PCI in AMI indicate that AMI itself influences PTX3 levels. PTX3 mRNA might be in response to fluctuations in circulating levels.

  3. Considerations on Radiation Protection in Portugal

    International Nuclear Information System (INIS)

    Simao, J.V.

    2006-01-01

    The author summarizes the main conclusions of a work group nominated by the Portuguese government in 2004 to propose measures to improve radiological protection in Portugal. The final report of this working group was presented to the Portuguese Government in 2005

  4. PTX-loaded three-layer PLGA/CS/ALG nanoparticle based on layer-by-layer method for cancer therapy.

    Science.gov (United States)

    Wang, Fang; Yuan, Jian; Zhang, Qian; Yang, Siqian; Jiang, Shaohua; Huang, Chaobo

    2018-05-17

    Poly (lactic-co-glycolic acid) (PLGA) nanoparticles are an ideal paclitaxel (PTX)-carrying system due to its biocompatibility and biodegradability. But it possessed disadvantage of drug burst release. In this research, a layer-by-layer deposition of chitosan (CS) and sodium alginate (ALG) was applied to modify the PLGA nanoparticles. The surface charges and morphology of the PLGA, PLGA/CS and PLGA/CS/ALG particles was measured by capillary electrophoresis and SEM and TEM, respectively. The drug encapsulation and loading efficiency were confirmed by ultraviolet spectrophotometer. The nanoparticles were stable and exhibited controlled drug release performance, with good cytotoxicity to human lung carcinoma cells (HepG 2). Cumulatively, our research suggests that this kind of three-layer nanoparticle with LbL-coated shield has great properties to act as a novel drug-loaded system.

  5. In Portugal, the energy revolution is underway

    International Nuclear Information System (INIS)

    Mary, Olivier

    2015-01-01

    As at the beginning of 2013, 70 per cent of the electricity consumed in Portugal had a renewable origin, this article outlines that this result is based on a strong-willed policy. In fact, Portugal entered the energy transition in 2001 with its '4E program' (energy efficiency and endogenous energies) which aimed at reaching 60 per cent of renewable energies in electricity consumption by 2020. This program was based on a strong development of wind and hydraulic energy. Moreover, the country developed its own capacities for the manufacturing of wind turbines. On another hand, other renewable energies (notably solar energy) seem a bit late although several projects are underway. As far as hydraulic energy, a dam project is a matter of controversy

  6. Biogas in Portugal: Status and public policies in a European context

    International Nuclear Information System (INIS)

    Ferreira, Miguel; Marques, Isabel Paula; Malico, Isabel

    2012-01-01

    The current status and legal framework of biogas production in Portugal are analyzed and compared to that of five other European countries, characterized by wide-ranging diversity of substrates and biogas applications. With this comparison, and with the calculation of the biogas energy potential in Portugal, the authors want to assess the significance of developing the Portuguese biogas sector. This study illustrates that the highest biogas feed-in tariffs are applied in the countries with a more developed sector. In Portugal, despite the fact that the organic effluents are a relevant energy source (873 Mm 3 biogas per year; 4889 GW h yr −1 ) and that new feed-in tariffs were established, biogas valorisation is still at an early stage. The importance of anaerobic digestion was only recognized in 2007 and the present installed power is about 10% of the potential electrical power (229 MW). Therefore, it is desirable to strengthen the national and regional biogas market. - Highlights: ► This work is a contribution to promote the development of national biogas sector. ► Current state of biogas production in EU is presented: five countries are considered. ► Portuguese legal framework on biogas is compared to other European countries. ► Organic effluents produced in Portugal are by themselves a relevant source of energy. ► The biogas sector in Portugal is still at an early stage of growth.

  7. A comparative study on music teacher preparation in Portugal and Brazil

    Directory of Open Access Journals (Sweden)

    Graça Mota

    2012-05-01

    Full Text Available The preparation of music teachers in Portugal and Brazil is the focus of this text, which aims at presenting preliminary aspects of a study in progress in the context of higher education in both countries. Inspired by comparative education methodology, the present study is investigating official documents and academic curricula offered in Portugal and Brazil for the music teachers’ preparation to promote, in different ways, the comparative reflection with an emphasis on school education. The music teachers’ education in both countries was analyzed taking into account the following elements: educational context in Portugal and Brazil; music preparation prior to higher education, and the entrance criteria in the courses that are offered for music teachers; curricular elements of the courses; teaching practice and professional perspectives. The preliminary results of this comparative analysis demonstrate similarities and differences in the two contexts: 1 in both countries, music teachers for regular schools receive their degrees in higher education institutions, and in Portugal, beyond the Licenciatura in Music, a Music Education Master degree is demanded; 2 in both countries specific entrance tests are accomplished in the universities, demanding previous musical knowledge; 3 the balance among the musical and pedagogical preparation is one of the curricular objectives; 4 the teaching practice is an emphasized component in the teachers’ preparation; 5 in Portugal, student’s motivation for the work in the regular school appears to be larger than in Brazil.

  8. International Uranium Resources Evaluation Project (IUREP) national favourability studies: Portugal

    International Nuclear Information System (INIS)

    1977-10-01

    Portugal is situated on the western edge of the Iberian Meseta. At present, its reasonably assured reserves are about 7800 t of U (including 1000 t of U at more than 830/lb U 3 O 8 ) and 850 t of U in estimated additional reserves. This potential is divided between vein deposits and deposits located in the peribatholithic schists or enclaved in granite. Two main districts share these reserves - Beira at the centre of the country and Alto Alentejo in the east, approximately at the same latitude as Lisbon. In spite of the considerable prospecting activities authorized by Portugal in the Meseta area, the subject cannot yet be regarded as exhausted. Additional resources may still be located in the horizontal and vertical extensions of the vein mineralizations or schists from the already known deposits or outside the districts containing such deposits. Moreover, certain post-Palaeozoic sedimentary basins exhibit features favourable for the presence of uranium-bearing deposits and therefore deserve to be taken into consideration. However, there are as yet no examples of economic mineralization in such locations in Portugal. All things considered, we considered it reasonable to place Portugal in category No. 3 of the classiffication adopted by BJREP. (author)

  9. Epidemiological review of Toxoplasma gondii infection in humans and animals in Portugal

    Science.gov (United States)

    Toxoplasmosis is a worldwide zoonosis. However, data from Portugal are limited and a considerable part of the literature is in Portuguese. Currently, the rate of congenital infection in Portugal is unknown, and almost nothing is known of sequelae of congenital toxoplasmosis. There is no general popu...

  10. Photovoltaic energy mini-generation: Future perspectives for Portugal

    International Nuclear Information System (INIS)

    Carvalho, Duarte; Wemans, Joao; Lima, Joao; Malico, Isabel

    2011-01-01

    This paper evaluates the benefits of developing the mini-generation PV market in Portugal. It presents the legal framework and current status of the Portuguese PV electricity sector, and compares the country to other European nations: France, Germany, Greece, Italy, Spain and the United Kingdom. A model that combines PVGIS with a self-developed financial tool is used to assess the feasibility of a 150 kW mini-generation system using five different technologies: fixed mount, single-axis tracking, double-axis tracking, low concentration and medium concentration (MCPV). The profitability of the mini-generation systems in the seven countries studied is calculated and compared. According to this analysis, MCPV and, of the conventional technologies, the single-axis tracking systems are the most profitable technologies. Despite the attractiveness of the current Portuguese feed-in tariffs and of the abundant solar resource, investors are discouraged and the country's PV market is far from mature. Specific mini-generation regulations should focus on a fast and transparent licensing procedure and should promote the access to financing. This would attract new investments, which would result in the growth of the PV electricity produced, and would help Portugal to meet its European Union Renewable Energy targets. - Highlights: → This work promotes the development of a mini-generation PV market in Portugal. → The Portuguese current status and legal framework is compared to other EU countries. → The profitability of 5 different PV technologies is compared for 7 European countries. → The Portuguese growth potential for PV energy is still big. → Portugal, due to its radiation levels, presents excellent investment opportunities.

  11. Social housing in Portugal and Denmark

    DEFF Research Database (Denmark)

    Alves, Sonia; Andersen, Hans Thor

    The social housing sector has become increasingly residualized and segregated in Portugal and Denmark. Whilst there is a considerable difference between the systems in these two countries, as regards issues of management and governance, dominant rent regimes (cost rent, social rent) or eligibility...

  12. Portugal 1780-1850

    Directory of Open Access Journals (Sweden)

    Fátima Sá e Melo Ferreira

    2007-01-01

    Full Text Available In this article are highlighted some of the main paths covered by the term “people”, in Portugal in the last decades of the XVIIIth century and in the first half of the XIXth century. The most significant semantic variations that the word suffered in the backdrop of the political conflicts caused by the establishment of Liberalism are investigated, taking in consideration that the modern political uses of this word arose with the French Invasions (1807-1811 and with the resistance to those invasions by a part of the Portuguese population.

  13. Clusters of abusive parenting: a latent class analysis of families referred to Child Protective Services in Portugal.

    Science.gov (United States)

    Matos, Ana Luísa; Moleiro, Carla; Dias, José G

    2014-12-01

    From the perspective of ecological models, it is suggested that a thorough behavior analysis of parental mistreatment and neglect is undertaken from a general approach to a more comprehensive and multi-dimensional perspective. Hence, the main goal of the present study was to determine if meaningful groups or clusters of abusive parenting in Portugal could be identified based on the characterization of the children and adolescents, their parents and context variables. An instrument was developed to assess variables of the children or adolescents, the family and the social context, all of which have been shown to be important in the literature. Child and Youth Protection Commissions from the whole of Portugal participated in the study, a total of 504 cases. Latent class analysis was applied in order to identify distinct parenting abusing behavior. The results showed four distinct clusters of families which are clearly defined in light of the types of risk and associated variables. The four groups are probabilistic and propose the composition of clusters with socio-demographic variables related to the types of risk. The significant interrelationships of different profiling characteristics are directly related to parenting abusing behavior. The results of this study confirmed our hypothesis of heterogeneous abusive parenting in Portugal. The findings yield useful policy-oriented results. Meaningfully organizing abusive parenting may be an important step not only in understanding the origins of abuse and neglect, but also in integrating this information into intervention models with children, young people and their families. Copyright © 2014 Elsevier Ltd. All rights reserved.

  14. Business creation in Portugal: Comparison between the World Bank data and Quadros de Pessoal

    OpenAIRE

    Elsa Morais Sarmento; Alcina Nunes

    2010-01-01

    Portugal has some of the highest business entry rates when compared to other countries, according to Eurostat, Statistics Portugal and the OECD Entrepreneurship Indicators Programme. We look at business creation in Portugal, from 2000 to 2007, by approaching two other complementary data sources, the World Bank Group Entrepreneurship Survey, based on official Portuguese business register’s and the universe of active employer enterprises, obtained by applying to the dataset Quadros de Pessoal, ...

  15. Information Management in Portugal: education and employment conditions and some prospects

    Directory of Open Access Journals (Sweden)

    Maria Cristina Vieira de Freitas

    2014-09-01

    Full Text Available The Professors Cristina Freitas and Maria da Graça Simões answer questions prepared by teachers from the Faculdade de Informação e Comunicação (Gestão da Informação Undergraduate Degree da Universidade Federal de Goiás - UFG. The questions are related to the educational structure dedicated to the issues of information management in Portugal, the influence of the "Big Data" phenomenon on education and training in the area - including discussions on data governance, the fundation areas of Information Management and the main approaches to information research in the Country. Besides, they discuss the employment conditions (threats and opportunities for professionals in Information Management in Portugal and in Europe [Available Language: Portuguese/Portugal].

  16. Prison Conditions in Portugal

    OpenAIRE

    Dores, António Pedro; Loureiro, Ricardo; Pontes, Nuno

    2013-01-01

    GENERAL DESCRIPTION OF THE PORTUGUESE PENITENTIARY SYSTEM Portugal has 51 prisons of different types: 15 penitentiaries (“central prisons”, normally larger ones) for inmates condemned to serve more than 6 months; 31 penitentiaries (“regional prisons”) for inmates condemned to serve less than 6 months; and five penitentiaries (“special prisons”) for inmates who need special attention, such as women, youths, policeman, and the sick (hospital). The first type of penitentiary has security...

  17. Millipedes (Diplopoda) from caves of Portugal

    DEFF Research Database (Denmark)

    P. S. Reboleira, Ana Sofia; Enghoff, Henrik

    2014-01-01

    in caves of the mainland and the island of Madeira has provided new data about the distribution and diversity of millipedes. A review of millipedes from caves of Portugal is presented, listing fourteen species belonging to eight families, among which six species are considered troglobionts...

  18. Portugal's experience with public-private partnerships

    NARCIS (Netherlands)

    Miranda Sarmento, J.J.; Renneboog, L.D.R.; Akintoye, A.; Beck, M.; Kumaraswamy, M.

    2015-01-01

    This paper documents the Portuguese experience in Public-Private Partnerships (PPPs). Since 1993, Portugal has been using PPPs intensively, mainly for highway construction and in the health sector. This has enabled the country to close the infrastructure gap and avoid the budget constraints at the

  19. ANALYSIS AND CHARACTERIZATION OF OZONE-RICH EPISODES IN NORTHEAST PORTUGAL

    Science.gov (United States)

    Carvalho, A.; Monteiro, A.; Ribeiro, I.; Tchepel, O.; Miranda, A.; Borrego, C.; Saavedra, S.; Souto, J. A.; Casares, J. J.

    2009-12-01

    Each summer period extremely high ozone levels are registered at the rural background station of Lamas d’Olo, located in the Northeast of Portugal. In average, 30% of the total alert threshold registered in Portugal is detected at this site. The main purpose of this study is to characterize the atmospheric conditions that lead to the ozone-rich episodes. Synoptic patterns anomalies and back trajectories cluster analysis were performed for a period of 76 days where ozone maximum concentrations were above 200 µg.m-3. This analysis was performed for the period between 2004 and 2007. The obtained anomaly fields suggested that a positive temperature anomaly is visible above the Iberian Peninsula. In addition, a strong wind flow pattern from NE is visible in the North of Portugal and Galicia, in Spain. These two features may lead to an enhancement of the photochemical production and to the transport of pollutants from Spain to Portugal. In addition, the 3D mean back trajectories associated to the ozone episode days were analysed. A clustering method has been applied to the obtained back trajectories. Four main clusters of ozone-rich episodes were identified, with different frequencies of occurrence: north-westerly flows (11%); north-easterly flows (45%), southern flow (4%) and westerly flows (40%). Both analyses highlight the NE flow as a dominant pattern over the North of Portugal. The analysis of the ozone concentrations for each selected cluster indicates that this northeast circulation pattern, together with the southern flow, is responsible for the highest ozone peak episodes. This also suggests that long-range transport of atmospheric pollutants may be the main contributor to the ozone levels registered at Lamas d’Olo. This is also highlighted by the correlation of the ozone time series with the meteorological parameters analysed in the frequency domain.

  20. Assessing International Product Design and Development Graduate Courses: The MIT-Portugal Program

    Science.gov (United States)

    Dori, Yehudit Judy; Silva, Arlindo

    2010-01-01

    The Product Design and Development (PDD) course is part of the graduate curriculum in the Engineering Design and Advanced Manufacturing (EDAM) study in the MIT-Portugal Program. The research participants included about 110 students from MIT, EDAM, and two universities in Portugal, Instituto Superior Técnico-Universidade Técnica de Lisboa (IST) and…

  1. El comercio de los esclavos musulmanes en el Portugal medieval : rutas y papel económico

    Directory of Open Access Journals (Sweden)

    François Soyer

    2010-01-01

    Full Text Available Actualmente existen muy pocos estudios acerca de la esclavitud musulmana en Portugal. Cuando se trata el comercio de los esclavos en la historia portuguesa, generalmente los trabajos se refieren al comercio de los esclavos africanos que los navegantes portugueses comenzaron traer de vuelta a Europa desde el año 1441 en adelante, a pesar de que desde el siglo XI existía una pobulación de esclavos musulmanes —los llamados mouros cativos—. En este artículo propongo estudiar, de la forma la más detallada posible, las características y dinámicas del comercio de los esclavos musulmanes en el reino cristiano de Portugal durante la Edad Media, tratando de responder a preguntas relevantes, como las de cuál era el origen y el papel económico de los esclavos musulmanes en el Portugal medieval, qué sabemos del comercio de los esclavos en aquel reino, o a la cuestión de si Portugal fue un país exportador o importador de esclavos.Whilst the presence of Muslim slaves in medieval Spain has attracted considerable scholarly attention from historians both inside and outside of the Iberian Peninsula, the same cannot be said of the history of Muslim slaves in the medieval Christian kingdom of Portugal. Most studies of slavery in Portugal focus on captives from sub-Saharan Africa brought back by Portuguese slavers to Europe from 1441 onwards even though Muslim slaves were present in Portugal from the eleventh century at the very least. We know next-to-nothing about these Muslim slaves. This article proposes to examine in as much detail as possible the characteristics and dynamics of the commerce of Muslim slaves in medieval Portugal. It addresses problematic questions regarding the origins and economic role of Muslim slaves in premodern Portugal, the nature of slave trading and whether Portugal was an importer or exporter of slaves.

  2. La electricidad en las relaciones España-Portugal

    Directory of Open Access Journals (Sweden)

    Cayetano Espejo Marín

    2004-12-01

    Full Text Available ELECTRICITY AND THE RELATIONS BETWEEN SPAIN AND PORTUGAL. From the early 1960s onwards, Spain and Portugal have maintained far-reaching programs for the exchange of electric power. These contacts have afforded, on the one hand, an increase in the security of electricity supply for both countries and, on the other, a better exploitation of their particular energy resources. The likely launching of the Iberian Electricity Market in April 2004 will lead to a new phase in the relations between Portugal and Spain. The new Market is based on three essential elements: i the expansion of electric links along their shared national borders, ii the setting up of a lone Operator for the single Iberian Market and iii the coordination of the two Operators that exist nowadays, RED ELÉCTRICA DE ESPAÑA and REDE ELÉCTRICA NACIONAL. The Iberian Electricity Market will be the first to comprise countries of the European Community only and it will generate one-tenth of the electric power consumed in Europe, being the fourth largest producer.

  3. O ambiente nas políticas públicas em Portugal

    Directory of Open Access Journals (Sweden)

    Margarida Queirós

    2002-06-01

    Full Text Available ENVIRONMENTAL PUBLIC POLICIES IN PORTUGAL – Despite almost thirty years of environmental activities with the first ‘environmental’ steps taken in Portugal in the early 1970s, it was only in the mid 1980s with Portugal’s joining the European Community that policy guidelines for environmental action were drawn up and established and later consolidated in the 1990s. In accordance with the general European trend, the Portuguese environmental policy was aimed atpreventive measures, at least in some areas. Portugal reflected on the issues over a period of time and defined environmental priorities in practically all areas of economic and social life. In terms of the state’s financial projects (central and local administration, strategy for environmental policies put the emphasis on undertakings that required heavy investment in infrastructures. This article describes the development of the government’s environmental policy in Portugal as reflected in the financial support given to environmental projects, according to industrial or geographical criteria, from the state budget. This process is addressed along with the development of the central administration and respective organisation of public services that handle environmental problems and such like. In this aspect, examination of the development of the environmental services structure and its concomitant duties demonstrates the importance given to environmental issues in public policies.

  4. Post-fire vegetation dynamics in Portugal

    Science.gov (United States)

    Gouveia, C.; Dacamara, C. C.; Trigo, R. M.

    2009-04-01

    The number of fires and the extent of the burned surface in Mediterranean Europe have increased significantly during the last three decades. This may be due either to modifications in land-use (e.g. land abandonment and fuel accumulation) or to climatic changes (e.g. reduction of fuel humidity), both factors leading to an increase of fire risk and fire spread. As in the Mediterranean ecosystems, fires in Portugal have an intricate effect on vegetation regeneration due to the complexity of landscape structures as well as to the different responses of vegetation to the variety of fire regimes. A thorough evaluation of vegetation recovery after fire events becomes therefore crucial in land management. In the above mentioned context remote sensing plays an important role because of its ability to monitor and characterise post-fire vegetation dynamics. A number of fire recovery studies, based on remote sensing, have been conducted in regions characterised by Mediterranean climates and the use of NDVI to monitor plant regeneration after fire events was successfully tested (Díaz-Delgado et al., 1998). In particular, several studies have shown that rapid regeneration occurs within the first 2 years after the fire occurrences, with distinct recovery rates according to the geographical facing of the slopes (Pausas and Vallejo, 1999). In 2003 Portugal was hit by the most devastating sequence of large fires, responsible by a total burnt area of 450 000 ha (including 280 000 ha of forest), representing about 5% of the Portuguese mainland (Trigo et al., 2006). The aim of the present work is to assess and monitor the vegetation behaviour over Portugal following the 2003 fire episodes. For this purpose we have used the regional fields of the Normalized Difference Vegetation Index (NDVI) as obtained from the VEGETATION-SPOT5 instrument, from 1999 to 2008. We developed a methodology to identify large burnt scars in Portugal for the 2003 fire season. The vegetation dynamics was then

  5. Assembling Toyota in Portugal

    OpenAIRE

    Machado, Tiago; Moniz, António

    2003-01-01

    A lot has been written over the last decade with regard to Toyota and the productive model associated to it (toyota-ism). And more specifically concerning the "(…) best-seller that changed the... sociological world" (Castillo, 1998: 31). But the case of Salvador Caetano’s Ovar Industrial Division (OID), that assembles Toyota light commercial vehicles in Portugal, allows us to put forward a sub-hypothesis that fits into the analysis schema proposed in the First GERPISA International Program – ...

  6. Taxation of Insolvent Companies: Empirical Evidence in Portugal

    Directory of Open Access Journals (Sweden)

    Ana Cristina dos Santos Arromba Dinis

    2016-04-01

    Full Text Available This article discusses the issue of taxation of insolvent companies in Portugal, particularly regarding the Portuguese tax on revenue of legal entities (IRC. For this purpose, first, some considerations on the legal framework of insolvent companies are woven and, second, their tax regime is analyzed. Then, a brief review of the main studies that, in the international context, analyze and debate major issues derived from the tax regime of insolvent companies is conducted, particularly in Brazil, Spain, United States, and Italy. Finally, there are the results of an empirical study conducted in Portugal, in 2013, which evaluates and compares the opinions of insolvency administrators (IA, the tax and customs authority (TA, and court magistrates (CM, in order to contribute to a better solution concerning business taxation under this regime. Respondents (IA, TA, CM demonstrate objective thinking about the fact they believe it is very important that the Portuguese Code of Insolvency and Business Recovery (CIRE and the Portuguese Code of Tax on Revenue of Legal Entities (CIRC are modified, now to make clear whether the settlement of property ownership of an insolvent estate is liable to the IRC, then to assign a chapter specifically devoted to the subject of taxation on insolvency in Portugal.

  7. Implementation of the NEAMTWS in Portugal

    Science.gov (United States)

    Matias, L. M.; Annunziato, A.; Carrilho, F.; Baptista, M.

    2008-12-01

    In this paper we present the ongoing implementation of a national tsunami warning system in Portugal. After the Sumatra event in December 2004, the UNESCO, through its International Oceanographic Commission, recognized the need for an end to end global tsunami warning system and International Coordination Groups have been established for different areas around the globe: Indian, Caribbean, Atlantic and Mediterranean ocean basins. This system is the natural response to the historical and recent instrumental events generated along the western segment of the Eurasia and Nubian plates, which eastern end corresponds to the Gulf of Cadiz. The TWS includes three main components: the seismic detection, the tsunami detection and the issue of warnings/alerts. In Portugal the automatic earthquake processing is installed at IM (Instituto de Meteorologia) which is the only national institution operating on a 24x7 basis. This makes IM the natural candidate to host the Portuguese tsunami warning system. The TWS under implementation has several key points: definition of the tsunami scenarios, tsunami detection, and tsunami protocol messages. The system will also be able to predict tsunami potential impact along the coast, wave-heights and arrival times at pre-defined locations along the coast. In this study we present the recent results on definition of tsunami scenarios, establishment of the scenario database and the tsunami analysis tool. This work is a joint effort between Instituto de Meteorologia (Portugal), the Joint Research Center, JRC- ISPRA, Italy and the coordination of the Portuguese Group for the implementation of NEAMTWS in the area. This work has been financed by different European projects as NEAREST and TRANSFER, and also by the JRC, the IM and CGUL/IDL institutions.

  8. Re-investigating the electricity consumption and economic growth nexus in Portugal

    International Nuclear Information System (INIS)

    Tang, Chor Foon; Shahbaz, Muhammad; Arouri, Mohamed

    2013-01-01

    In the previous decades, a number of studies have been conducted to analyse the causal relationship between electricity consumption and economic growth in the Portuguese economy. However, the evidence remains controversial because the previous studies do not provide clear causality evidence. This might be attributed to the omitted variables bias because most previous studies only focus on the relationship between electricity consumption and economic growth in a bi-variate model. This paper attempts to re-investigate the relationship between electricity consumption and economic growth in Portugal using a multivariate model. Based on the bounds testing approach to cointegration and the Granger causality test within the vector error-correction model (VECM), our empirical results confirm the presence of cointegration among the variables. Moreover, there is evidence of bi-directional causality between electricity consumption and economic growth in the short- and long-run. This suggests that energy is an important source of economic growth in Portugal. Therefore, energy conservation policies should not be implemented because it would deteriorate the process of economic growth and development of the Portuguese economy. - Highlights: • Electricity consumption and economic growth series in Portugal are cointegrated. • There is evidence of feedback effects between the two variables. • Energy is an important source of economic growth in Portugal

  9. Predictors of loneliness among students and nuns in Angola and Portugal.

    Science.gov (United States)

    Neto, Félix; Barros, José

    2003-07-01

    The authors conducted 2 studies to examine the relationship between loneliness and psychosocial variables among people from Angola and Portugal. In the 1st study, the participants were 129 college students from Angola and 122 from Portugal, and in the 2nd study participants were 105 nuns from Angola and 74 from Portugal. The following instruments were administered to all participants in both studies: the Revised UCLA Loneliness Scale (D. Russell, L. Peplau, & C. Cutrona, 1980), the Neuroticism Scale (J. Barros, 1999), the Optimism Scale (J. Barros, 1998), and the Satisfaction With Life Scale (E. Diener, R. Emmons, R. Larsen, & S. Griffin, 1985). Ethnic differences were found in loneliness. The Angolan participants recorded higher scores for loneliness than did the Portuguese participants. For both samples the most prominent predictors of loneliness were neuroticism and dissatisfaction with life.

  10. The demand factors for cesareans in Portugal – some preliminary results

    OpenAIRE

    Tavares, Aida Isabel; Rocha, Tania

    2012-01-01

    The aim of this work is to determine the demand factors for cesareans in Portugal. This work is exploratory and preliminary. Data is aggregated in NUTSII , for the period 2002-10. The number of cesareans performed is count data which requires the estimation of this panel data by a negative binomial with fixed effects. The main result is the evidence that there may be induced demand for cesareans in Portugal. Further research is needed.

  11. Mapping the networks of cancer research in Portugal: first results

    Energy Technology Data Exchange (ETDEWEB)

    Bras, O.R.; Cointet, J.P.; Nunes, J.A.; David, L.; Cambrosio, A.

    2016-07-01

    Social studies of cancer research at the international level have contributed to a better understanding of the developmental dynamics – both organizational and epistemic – of this field (Keating & Cambrosio, 2012). In contrast, despite its robust development, oncology research in Portugal has been the subject of only few studies. Most of them have a strong focus on the first half of the 20th century (Raposo, 2004; Costa, 2010, 2012a; 2012b), while a few focus on more contemporary events (Nunes, 2001). Consequently, we do not have a clear picture of recent trends in oncology research in Portugal, and how it integrates into the international landscape. This hinders public accountability of oncology research while also limiting the analysis of how this research relates to health care delivery, health outcomes, and health policy formulations. This paper presents the first results of an ongoing research project on the organizational and epistemic development of oncology research in Portugal, covering the period from the end of the 20th century to 2015. Among other issues, we intend to explore the extent to which oncology research in Portugal mirrors the international dynamics at a smaller scale, and the extent to which it presents features of its own. The study draws upon computer-based analysis of publications using the platform CorText (http://www.cortext.net/) of IFRIS (Institut Francilien Recherche, Innovation, Société), along with interviews with Portuguese oncologists and related practitioners. (Author)

  12. Grow your own REE deposits: Novel observations from the soils of Southern Portugal

    Science.gov (United States)

    Hardy, Liam; Smith, Martin; Boyce, Adrian; McDonald, Alison; Heller, Shaun; Bamberger, Axel; Blum, Astrid; Hood, Leo

    2017-04-01

    Industrialised eucalyptus farming in Serra de Monchique has been well documented for its regional impacts on water flow, for its destructive centralisation of local economics (Jenkins, 1979) and for its derogatory impacts on local ecology (Brito, 1999) (Matias & Lamberts, 2011), it is another story of cash cropping for short term gain in an area of sensitive environmental balance which had previously been suitably subsistence farmed for some 700 years with no outside influence until the early 1950s (Jenkins, 1979). The farming has irreversibly changed local customs, soil and water systems, but formed new and intricate relationships between the troposol, oxisol and latosol formations and plants which have not previously been studied in this region in terms of soil geochemistry. During research in the region (as part of the SoS Rare/NERC-UK program) into metal and clay interactions in the troposol formations of Monchique, it was noted that rare earth elements (REEs) and other soluble ions were being mobilised in the upper half of the profiles by some seasonal cycle other than the natural meteoric input/leaching expected during classical lateritisation (Tardy, 1997). It was observed that some 40% of Fe and some 30% of Y were leaving the profile during wet season and concentrating at specific depths during dry seasons to a grade of some 160ppm Y and were thus, potentially viable as an economic resource of Heavy REEs. This PICO presentation discusses the proposed anthropogenic/biogenic mechanism for this concentration and how you too could potentially grow an economically viable REE enriched garden. References: Brito, J. G. (1999). Management strategies for conservation of the lizard Lacerta schreiberi in Portugal. Biological conservation, 311-319. Jenkins, R. (1979). The Road to Alto: An account of peasants, capitalists and their soil in the mountains of Southern Portugal. London: Pluto, ISBN: 0861040767. Matias, M., & Lamberts, P. (2011, May 26). Parliamentary

  13. Societal costs and burden of otitis media in Portugal

    Directory of Open Access Journals (Sweden)

    Speets AM

    2011-04-01

    Full Text Available Anouk Speets1, Judith Wolleswinkel1, Cristina Cardoso21Pallas health research and consultancy, Rotterdam, the Netherlands; 2GlaxoSmithKline, Algés, PortugalAbstract: This study aimed to estimate the resource consumption and societal impact of otitis media (OM in children younger than five years of age in Portugal. An Internet survey on generic childhood symptoms and diseases was administered to a sample of parents. This self-report survey had been previously implemented in other European countries. Medically confirmed OM was defined as symptoms of earache or “running ear” and/or a diagnosis of OM provided by a medical doctor. Direct medical, nonmedical, and indirect nonmedical costs were calculated for individual cases. Mean total costs per OM episode were estimated at €334. This corresponds to an estimated societal impact of 72 million €/year, of which 39% were indirect nonmedical costs. An epidemiological study should help to confirm the results of this study, and evaluate whether an intervention to reduce the occurrence and/or duration of OM may have an impact on societal costs and quality of life for affected families.Keywords: otitis media, costs, societal burden, Portugal

  14. Judeus de Castela em Portugal no final da Idade Media: onomástica familiar e mobilidade

    Directory of Open Access Journals (Sweden)

    Ferro Tavares, María José

    2014-06-01

    Full Text Available Using mainly unpublished sources of the royal chancery and Inquisition proceedings the author provides profiles of individuals and their families among a Jewish minority of Spanish origin in Portugal from the restoration of the Avis dynasty (1383 to the forced baptism and the expulsions and forced baptism of the Jews. The first part identifies Spanish-Jewish last names found in the sources as the last names of many Jews could indicate their geographic origin or that of their immediate ancestors. Special attention is given to a selection of these families (Navarro, Menir, Abravanel. In the second part, it is exemplified the mobility of the Jewish immigrants as a consequence of the social and political instability.Judíos de Castilla en Portugal a finales de la Edad Media: onomástica familiar y movilidad Mediante el recurso a documentación en buena medida inédita de la cancillería real y procesos inquisitoriales, la autora realiza una lectura diacrónica de la presencia y establecimiento de judíos de origen hispánico en Portugal desde la instauración de la Casa de Avís y hasta después del bautismo forzado de 1497. La primera parte del estudio está dedicada al análisis de la onomástica hispano-judía, partiendo de la premisa de que el sobrenombre de algunos judíos puede indicar su naturalidad u origen toponímico (o el de sus antepasados inmediatos, con especial detenimiento en las familias Navarro, Menir (desmiente la tradicional identificación entre ambos linajes y Abravanel. En la segunda parte se exponen ejemplos de la movilidad de los judíos llegados al reino como consecuencia de la inestabilidad social y las políticas regias.

  15. 'Greenfields' and 'Brownfields': automotive industrial development in the UK and in Portugal

    Directory of Open Access Journals (Sweden)

    Mário Vale

    1996-12-01

    Full Text Available The industrial policy in the UK and in Portugal, as in most EU countries, seeks to attract new investment capacity, to create jobs and to promote the impact of the so-called "demonstration efect" of "greenfield" development strategies pursued in the new plants of inward investors on existing or "brownfield" plants. This industrial policy focus is particularly evident in the automobile industry.This paper compares the industrial policy oriented towards the automobile industry in the UK and in Portugal. Two recent "greenfield" investments are analised: Nissan in the North-East region (UK and Ford/VW in the Setúbal Peninsula (Portugal, as well as three "brownfield" plants: Ford Halewood and GM Vauxhall Ellesmere Port in the North-West region (UK and Renault in Setúbal (Portugal. The first part starts with a discussion of industrial policy in the automobile sector, the role of "greenfield" development strategies and the "demonstration effect" on "brownfield" plants. Then, the limits of new inward investment are pointed out, basically their problems and restrictions. Afterwards, the structural barriers to the "demonstration effect" within "brownfield" plants are outlined and some possabilities for alternative "brownfield" development strategies are presented.

  16. Safety and Efficacy of Low-dose Nanoparticle Albumin-bound Paclitaxel for HER2-negative Metastatic Breast Cancer.

    Science.gov (United States)

    Takashima, Tsutomu; Kawajiri, Hidemi; Nishimori, Takeo; Tei, Seika; Nishimura, Shigehiko; Yamagata, Shigehito; Tokunaga, Shinya; Mizuyama, Yoko; Sunami, Takeshi; Tezuka, Kenji; Ikeda, Katsumi; Ogawa, Yoshinari; Kashiwagi, Shinichiro; Noda, Satoru; Onoda, Naoyoshi; Ishikawa, Tetsuro; Kudoh, Shinzoh; Takada, Minoru; Hirakawa, Kosei; Ohira, Masaichi

    2018-01-01

    Nab-paclitaxel (nab-PTX) is an albumin-bound paclitaxel formulation. Although nab-PTX has shown superior efficacy compared to conventional paclitaxel (PTX) in metastatic breast cancer (MBC), chemotherapy-induced peripheral neuropathy (CIPN) was more frequently observed in nab-PTX. In this study, we aimed to estimate the feasibility of the nab-PTX 175 mg/m 2 /3weeks regimen. Patients having metastatic or inoperable HER2-negative breast cancer received 175 mg/m 2 of nab-PTX every three weeks. The primary endpoint was safety and the secondary endpoints were response and survival. Seventeen patients were enrolled with a median age of 64 years. Ten patients had estrogen receptor positive disease and seven had triple-negative disease. CIPN was observed in seven patients (41%) however, grade 3 CIPN was only seen in one patient (6%). Objective response rate was 41% and progression-free survival was 23 weeks. Nab-PTX 175 mg/m 2 /3wks regimen has a good safety profile and less frequent CIPN. This regimen can contribute to the strategy of MBC treatment. Copyright© 2018, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

  17. Population mobility and the changing epidemics of HIV-2 in Portugal

    DEFF Research Database (Denmark)

    Carvalho, A C; Valadas, E; França, L

    2012-01-01

    Portugal is the European country with the highest frequency of HIV-2 infection, which is mainly concentrated in West Africa. The cumulative number of notified HIV-2 infections in Portugal was 1813 by the end of December 2008. To better characterize the dynamics of HIV-2 infection in the country a...... and to obtain data that may be of use in the prevention of the spread of HIV-2, we evaluated a large pooled sample of patients....

  18. Heart failure in numbers: Estimates for the 21st century in Portugal.

    Science.gov (United States)

    Fonseca, Cândida; Brás, Daniel; Araújo, Inês; Ceia, Fátima

    2018-02-01

    Heart failure is a major public health problem that affects a large number of individuals and is associated with high mortality and morbidity. This study aims to estimate the probable scenario for HF prevalence and its consequences in the short-, medium- and long-term in Portugal. This assessment is based on the EPICA (Epidemiology of Heart Failure and Learning) project, which was designed to estimate the prevalence of chronic heart failure in mainland Portugal in 1998. Estimates of heart failure prevalence were performed for individuals aged over 25 years, distributed by age group and gender, based on data from the 2011 Census by Statistics Portugal. The expected demographic changes, particularly the marked aging of the population, mean that a large number of Portuguese will likely be affected by this syndrome. Assuming that current clinical practices are maintained, the prevalence of heart failure in mainland Portugal will increase by 30% by 2035 and by 33% by 2060, compared to 2011, resulting in 479 921 and 494 191 affected individuals, respectively. In addition to the large number of heart failure patients expected, it is estimated that the hospitalizations and mortality associated with this syndrome will significantly increase its economic impact. Therefore, it is extremely important to raise awareness of this syndrome, as this will favor diagnosis and early referral of patients, facilitating better management of heart failure and helping to decrease the burden it imposes on Portugal. Copyright © 2017 Sociedade Portuguesa de Cardiologia. Publicado por Elsevier España, S.L.U. All rights reserved.

  19. Poverty and precarity in Portugal

    OpenAIRE

    Carvalho, Izaura

    2016-01-01

    This research assesses poverty levels in Portugal within a multidimensional approach, over a period from 2008 to 2014. Further, it aims at inferring a causal relationship between precarious jobs and the estimated multidimensional poverty level. This research adds to the existing literature by applying a discrete choice experiment in the construction of the poverty index, as well as by nding causality between poverty and precarity. Empirical results suggest that, while multidim...

  20. Does Trade Help to Explain Tourism Demand? The Case of Portugal

    Directory of Open Access Journals (Sweden)

    Nuno Carlos LEITÃO

    2010-03-01

    Full Text Available The tourism industry has expanded in recent years due to internal and external environmental forces. These forces, income, trade, consumer price, and geographical distance are interconnected. Accounting for imperfect competition and increasing returns to scale, the new trade theory offers the explanation of dynamic gains from international trade. A large number of studies attempt to test the hypothesis that there is a link between trade and tourism. Most of the studies show that trade and tourism are positively correlated. This paper specifies static and dynamic panel demand models for tourism in Portugal and estimates demand equations using tourist inflow data for the period 1995-2006. We find that bilateral trade, immigration, border, and geographical distance between Portugal and countries of origin are the main determinants of tourism to Portugal. The dynamic panel data approach indicates that trade, population, and income are more important determinants than relative price.

  1. Competitiveness in the Southern Euro Area; France, Greece, Italy, Portugal, and Spain

    OpenAIRE

    Bogdan Lissovolik; Julio Escolano; Stefania Fabrizio; Werner Schule; Herman Z Bennett; Stephen Tokarick; Yuan Xiao; Marialuz Moreno Badia; Eva Gutierrez; Iryna V. Ivaschenko

    2008-01-01

    This collection of studies analyzes developments in nonprice external competitiveness of France, Greece, Italy, Portugal, and Spain. While France, Italy, and Portugal have experienced substantial export market share losses, Greece and Spain performed relatively well. Export market share losses appear associated with rigidities in resource allocation (sectoral, geographical, technological) relative to peers and lower productivity gains in high value-added sectors. Disaggregated analysis of goo...

  2. A new model for cork weight estimation in Northern Portugal with methodology for construction of confidence intervals

    Science.gov (United States)

    Teresa J.F. Fonseca; Bernard R. Parresol

    2001-01-01

    Cork, a unique biological material, is a highly valued non-timber forest product. Portugal is the leading producer of cork with 52 percent of the world production. Tree cork weight models have been developed for Southern Portugal, but there are no representative published models for Northern Portugal. Because cork trees may have a different form between Northern and...

  3. Post-fire vegetation recovery in Portugal based on spot/vegetation data

    Science.gov (United States)

    Gouveia, C.; Dacamara, C. C.; Trigo, R. M.

    2010-04-01

    A procedure is presented that allows identifying large burned scars and the monitoring of vegetation recovery in the years following major fire episodes. The procedure relies on 10-day fields of Maximum Value Composites of Normalized Difference Vegetation Index (MVC-NDVI), with a 1 km×1 km spatial resolution obtained from the VEGETATION instrument. The identification of fire scars during the extremely severe 2003 fire season is performed based on cluster analysis of NDVI anomalies that persist during the vegetative cycle of the year following the fire event. Two regions containing very large burned scars were selected, located in Central and Southwestern Portugal, respectively, and time series of MVC-NDVI analysed before the fire events took place and throughout the post-fire period. It is shown that post-fire vegetation dynamics in the two selected regions may be characterised based on maps of recovery rates as estimated by fitting a monoparametric model of vegetation recovery to MVC-NDVI data over each burned scar. Results indicated that the recovery process in the region located in Central Portugal is mostly related to fire damage rather than to vegetation density before 2003, whereas the latter seems to have a more prominent role than vegetation conditions after the fire episode, e.g. in the case of the region in Southwestern Portugal. These differences are consistent with the respective predominant types of vegetation. The burned area located in Central Portugal is dominated by Pinus Pinaster whose natural regeneration crucially depends on the destruction of seeds present on the soil surface during the fire, whereas the burned scar in Southwestern Portugal was populated by Eucalyptus that may quickly re-sprout from buds after fire. Besides its simplicity, the monoparametric model of vegetation recovery has the advantage of being easily adapted to other low-resolution satellite data, as well as to other types of vegetation indices.

  4. High ozone levels in the northeast of Portugal: Analysis and characterization

    Science.gov (United States)

    Carvalho, A.; Monteiro, A.; Ribeiro, I.; Tchepel, O.; Miranda, A. I.; Borrego, C.; Saavedra, S.; Souto, J. A.; Casares, J. J.

    2010-03-01

    Each summer period extremely high ozone levels are registered at the rural background station of Lamas d'Olo, located in the Northeast of Portugal. In average, 30% of the total alert threshold registered in Portugal is detected at this site. The main purpose of this study is to characterize the atmospheric conditions that lead to the ozone-rich episodes at this site. Synoptic patterns anomalies and back trajectories cluster analysis were performed, for the period between 2004 and 2007, considering 76 days when ozone maximum hourly concentrations were above 200 μg m -3. The obtained atmospheric anomaly fields suggested that a positive temperature anomaly is visible above the Iberian Peninsula. A strong wind flow pattern from NE is observable in the North of Portugal and Galicia, in Spain. These two features may lead to an enhancement of the photochemical production and to the transport of pollutants from Spain to Portugal. In addition, the 3D mean back trajectories associated to the ozone episode days were analysed. A clustering method has been applied to the obtained back trajectories. Four main clusters of ozone-rich episodes were identified, with different frequencies of occurrence: north-westerly flows (11%); north-easterly flows (45%), southern flow (4%) and westerly flows (40%). Both analyses highlight the NE flow as a dominant pattern over the North of Portugal during summer. The analysis of the ozone concentrations for each selected cluster indicates that this northeast circulation pattern, together with the southern flow, are responsible for the highest ozone peak episodes. This also suggests that long-range transport of atmospheric pollutants is the main contributor to the ozone levels registered at Lamas d'Olo. This is also highlighted by the correlation of the ozone time-series with the meteorological parameters analysed in the frequency domain.

  5. Portugal unido y separado. Propaganda y discurso identitario entre Austrias y Braganzas

    Directory of Open Access Journals (Sweden)

    Pedro Cardim

    2014-03-01

    Full Text Available Este artículo analiza el tratado Portugal unido y separado…, escrito por Pedro de Valenzuela y publicado en Madrid en 1659. El prelado Pedro Valenzuela defiende la restauración de la soberanía habsbúrgica en Portugal (la corona portuguesa se había separado de la Monarquía de España en 1640 a través de una imagen profundamente influenciada por su lealtad política. La primera parte de este trabajo está, por lo tanto, dedicada al análisis del tratado de Valenzuela. En la segunda y última parte las ideas de Valenzuela son integradas en un contexto para demostrar que muchos de los asuntos que aparecen en su obra venían discutiéndose desde por lo menos finales del siglo XVI no solamente en Portugal, sino en varias partes de la Península Ibérica. Esta circunstancia evidencia que para captar el significado completo de los planteamientos de Valenzuela es indispensable tener en cuenta el marco ibérico.This article analyses the treatise Portugal unido y separado…, written by Pedro de Valenzuela and printed in Madrid in 1659. The clergyman Pedro Valenzuela supported the restoration of the Habsburg sovereignty in Portugal (the Portuguese crown had split from the Spanish Monarchy in 1640, and the picture he conveys is largely influenced by his political allegiance. The first part of this study is therefore dedicated to an analysis of Valenzuela’s treatise. In the second and final part of this article the ideas expressed by Valenzuela are set in context. It is then demonstrated that many of the issues raised in this book were being discussed since, at least, the late 16th century, not only in Portugal but also in various parts of the Iberian Peninsula. It is thus argued that, in order to capture the full meaning of the questions raised by Valenzuela, it is indispensable to take into account their Iberian context.

  6. Rickettsioses in Latin America, Caribbean, Spain and Portugal

    Directory of Open Access Journals (Sweden)

    Marcelo B. Labruna

    2011-05-01

    Full Text Available Data on genus and infectious by Rickettsia were retrospectively compiled from the critical review literature regarding all countries in Latin America, Caribbean islands, Portugal and Spain. We considered all Rickettsia records reported for human and/or animal hosts, and/or invertebrate hosts considered being the vector. In a few cases, when no direct detection of a given Rickettsia group or species was available for a given country, the serologic method was considered. A total of 13 Rickettsia species have been recorded in Latin America and the Caribbean. The species with the largest number of country confirmed records were Rickettsia felis (9 countries, R. prowazekii (7 countries, R. typhi (6 countries, R. rickettsii (6 countries, R. amblyommii (5 countries, and R. parkeri (4 countries. The rickettsial records for the Caribbean islands (West Indies were grouped in only one geographical area. Both R. bellii, R. akari, and Candidatus ‘R. andeane’ have been recorded in only 2 countries each, whereas R. massiliae, R. rhipicephali, R.monteiroi, and R. africae have each been recorded in a single country (in this case, R. africae has been recorded in nine Caribbean Islands. For El Salvador, Honduras, and Nicaragua, no specific Rickettsia has been reported so far, but there have been serological evidence of human or/and animal infection. The following countries remain without any rickettsial records: Belize, Venezuela, Guyana, Surinam, and Paraguay. In addition, except for a few islands, many Caribbean islands remain without records. A total of 12 Rickettsia species have been reported in Spain and Portugal: R. conorii, R. helvetica, R. monacensis, R. felis, R. slovaca, R. raoultii, R. sibirica, R. aeschlimannii, R. rioja, R. massiliae, R. typhi, and R. prowazekii. Amongst these Rickettsia species reported in Spain and Portugal, only R. prowazekii, R. typhi, R. felis, and R. massiliae have also been reported in Latin America. This study summarizes

  7. Pentoxifylline regulates the cellular adhesion and its allied receptors to extracellular matrix components in breast cancer cells.

    Science.gov (United States)

    Goel, Peeyush N; Gude, Rajiv P

    2014-02-01

    Pentoxifylline (PTX) is a methylxanthine derivative that improves blood flow by decreasing its viscosity. Being an inhibitor of platelet aggregation, it can thus reduce the adhesiveness of cancer cells prolonging their circulation time. This delay in forming secondary tumours makes them more prone to immunological surveillance. Recently, we have evaluated its anti-metastatic efficacy against breast cancer, using MDA-MB-231 model system. In view of this, we had ascertained the effect of PTX on adhesion of MDA-MB-231 cells to extracellular matrix components (ECM) and its allied receptors such as the integrins. PTX affected adhesion of breast cancer cells to matrigel, collagen type IV, fibronectin and laminin in a dose dependent manner. Further, PTX showed a differential effect on integrin expression profile. The experimental metastasis model using NOD-SCID mice showed lesser tumour island formation when treated with PTX compared to the control. These findings further substantiate the anti-adhesive potential of PTX in breast cancer and warrant further insights into the functional regulation. Copyright © 2013 Elsevier Masson SAS. All rights reserved.

  8. Maculinea alcon exploits Myrmica aloba in Portugal

    DEFF Research Database (Denmark)

    Arnaldo, P.S.; Wynhoff, I.; Soares, P.

    2011-01-01

    Larvae of the obligate myrmecophilous social parasite Maculinea alcon (Lepidoptera: Lycaenidae) were found exclusively using Myrmica aloba (Hymenoptera: Formicidae) ant hosts in NE-Portugal. This is the first record of the host ant usage of any Maculinea species in Portugal, and of any Maculinea ...... using M. aloba nests. These results on such peripheral European populations confirm that knowledge of the local host ant species is crucial for the successful protection of these endangered butterflies, and vital for examining the evolution of such interactions...

  9. Regulation, circulation and distribution of penicillin in Portugal (1944-1954).

    Science.gov (United States)

    Bell, Victoria; Rui Pita, João; Pereira, Ana Leonor

    Portugal did not participate in World War II but was one of the first countries in the world to receive penicillin for civilian use. The Portuguese Red Cross began to import the antibiotic from the United States of America in 1944 and appointed a controlling committee to oversee its distribution, due to the small amount available. In 1945, as world production increased, penicillin began to be distributed through the normal channels. An important role in its regulation was played by the official department responsible for controlling pharmaceutical and chemical products in Portugal, the Comissão Reguladora dos Produtos Químicos e Farmacêuticos (Regulatory Committee for Chemical and Pharmaceutical Products). Penicillin was imported as a raw material from 1947 and the first medicaments containing penicillin, prepared in Portugal, were released into the commercial circuit in 1948. A laboratory had been established in 1942 by the Comissão Reguladora for the analytical verification of medicaments and medicinal products with the aim of certifying their quality and minimizing the number of products with no attested therapeutic efficacy. The number of medicaments analysed by this laboratory increased substantially from 72 in the year of its foundation (1942) to 2478 in 1954, including, after 1948, medicaments containing penicillin. The aim of the present paper was to elucidate the role of the Comissão Reguladora dos Produtos Químicos e Farmacêuticos in regulating and controlling the distribution of penicillin in Portugal during the 1940s and 1950s.

  10. Community-associated methicillin-resistant Staphylococcus aureus infection in Portugal

    Directory of Open Access Journals (Sweden)

    R. Nazareth

    2012-01-01

    Full Text Available Methicillin-resistant Staphylococcus aureus (MRSA has recently emerged as a cause of community-acquired infections among individuals without risk factors. Community-associated MRSA (CA-MRSA appears to be more virulent, causing superficial mild skin and soft tissue infections to severe necrotizing fasciitis, and in rare cases, pneumonia.Community-associated MRSA was first reported in Australia in the early 80s, after almost two decades in the USA, and then in several countries in Europe, Asia and South America. No data exists in Portugal.We report the first case of CA-MRSA infection in Portugal, in a young adult with severe necrotizing pneumonia, complicated with bilateral empyema and respiratory failure. Resumo: Recentemente assistiu-se à emergência de infeções na comunidade por Staphylococcus aureus meticilina-resistente (MRSA em indivíduos sem fatores de risco. O MRSA associado à comunidade (CA-MRSA parece ser mais virulento, causando desde infeções superficiais da pele e tecidos moles até fasceíte necrosante e, raramente, pneumonia.O CA-MRSA foi inicialmente identificado na Austrália no início da década de 80 e, após cerca de duas décadas, surgiu nos EUA e em vários países da Europa, Ásia e América do Sul. Não existe informação disponível acerca da prevalência em Portugal.Os autores reportam o primeiro caso de infeção por CA-MRSA em Portugal, num adulto jovem com pneumonia necrotizante grave complicada por empiema bilateral e insuficiência respiratória. Keywords: Community-associated, MRSA, Staphylococcus aureus, Necrotizing pneumonia, Empyema, Palavras-chave: comunidade associada, MRSA, Staphylococcus aureus, pneumonia necrosante, empiema

  11. La desestabilización de Portugal en 1891 y la posición española

    Directory of Open Access Journals (Sweden)

    Pascual Serrano Sirvent

    1997-01-01

    Full Text Available Entre 1890 y 1893 Portugal vivió, como consecuencia del ultimátum inglés del 11 de enero de 1890, una época de profunda inestabilidad política interna además de una fuerte crisis financiera que la agravó. En este momento, la Reina Viuda de Portugal, María Pía, con el conocimiento del Gobierno portugués, comenzó a hacer unas consultas a la Reina Regente María Cristina y el Gobierno español pidiendo una acción militar contra una posible revolución republicana con la aceptación de las primeras potencias europeas. Resultó que las primeras potencias europeas querían la permanencia del principio monárquico en Portugal, con una posible ayuga militar española al ejército de Portugal.Between 1890 and 1893, as a result of the English ultimátum of 11h January 1890, Portugal went through a period of great instability, and also a great financial crack that turned into a political crack. This caused Widow Queen María Pía, with some knowledge of thíe Portuguese Gouvernmwnt, to ask Regent Queen María Cristina and the Spanish Gouvernment to help the Spanish Army against a possible republican revolution in Portugal, with the agreement of the main European powers. As a result, the main European powers wanted to keep the monarchy in Portugal, with the possible aid of the Spanish Army.

  12. Portugal; Request for a Three-Year Arrangement Under the Extended Fund Facility

    OpenAIRE

    International Monetary Fund

    2011-01-01

    Portugal's economy faced severe crisis during the global economic and financial crisis. In this context, Portugal's authorities have put forward an economically well-balanced program that will focus on structural reforms to boost growth and employment, ensure balanced fiscal sustainability, safeguard financial stability, and prevent a credit crunch. The Executive Board of the International Monetary Fund welcomed this step, and approved a three-year arrangement under the Extended Fund Facility...

  13. Understanding differences in cervical cancer incidence in Western Europe: comparing Portugal and England.

    Science.gov (United States)

    Mendes, Diana; Mesher, David; Pista, Angela; Baguelin, Marc; Jit, Mark

    2018-04-01

    Cervical cancer incidence has decreased over time in England particularly after the introduction of organized screening. In Portugal, where opportunistic screening has been widely available with only slightly lower coverage than that of the organized programme in England, rates of cervical cancer have been higher than in England. We compared the burden of cervical cancer, risk factors and preventive interventions over time in both countries, to identify elements hindering the further decline in incidence and mortality in Portugal. We used joinpoint regression to identify significant changes in rate time-trends. We also analyzed individual-level Portuguese data on sexual behaviour and human papillomavirus prevalence, and recent aggregate data on organized and opportunistic screening coverage. We compared published estimates of survival, risk factors and historical screening coverage for both countries. Despite stable incidence, cervical cancer mortality has declined in both countries in the last decade. The burden has been 4 cases and 1 death per 100 000 women annually higher in Portugal than in England. Differences in human papillomavirus prevalence and risk factors for infection and disease progression do not explain the difference found in cervical cancer incidence. Significant mortality declines in both countries followed the introduction of different screening policies, although England showed a greater decline than Portugal over nearly 2 decades after centralizing organized screening. The higher rates of cervical cancer in Portugal compared to England can be explained by differences in screening quality and coverage.

  14. The historical and recent distribution and status of mammals in Portugal

    Directory of Open Access Journals (Sweden)

    Margarida Santos-Reis

    1996-12-01

    Full Text Available Abstract Historical and recent data on Portuguese mammals are presented in this paper, occurring on the mainland and/or in the Azores and Madeira Atlantic islands. Nowadays, 95 species of mammals are known in Portugal, of which only one (Nyctalus azoreum is an endemic species and three others (Pipistrellus maderensis, Microtus cabrerae and Lynx pardina are exclusive for Portugal and Spain. Moreover, two other species, Mustela vison and Sciurus vulgaris are recent records for the Portuguese fauna, the first due to an accidental introduction and the second resulting from a recolonization by Spanish populations. Of the remaining species, around 50% (46 species are threatened in different degrees, 34.8% (16 species being considered endangered or vulnerable. Mammals extinct in Portugal are the Gerês goat (Capra pyrenaica lusitanica and the bear (Ursus arctos.

  15. FAMILY HEALTH MANAGEMENT AND POVERTY IN AN ECONOMIC RECESSION PERIOD IN PORTUGAL

    OpenAIRE

    Carvalho, Ana Branca; Oliveira, Ivo; Nogueira, Fernanda

    2015-01-01

    Abstract: The main purpose of this article, in the management and health, was to assess the contribution of family health and its role in local development in the context of economic recession and worsening poverty in Portugal. Material and Methods. Data were collected through the questionnaire, 1021 individuals were inquired in Portugal, with statistical treatment through inferential analysis, factorial and regression. They were asked to participate voluntarily in writing through email pa...

  16. Regulation of clinical research and bioethics in Portugal.

    Science.gov (United States)

    Carvalho, Fatima Lampreia

    2007-06-01

    This article presents an overview of the Portuguese transposition of the European Directive on Good Clinical Practice (2001/20/E) concerning scientific and academic debates on bioethics and clinical investigation. Since the Directive was transposed into Portuguese law by its National Assembly, the bureaucracy of clinical trials has been ever more complex. Despite demands for swift application processes by the Pharmaceutical industry, supported by the European Parliament, the Directive's transcription to the national law has not always delivered the expected outcome. However, this has led to an increased number of applications for clinical trials in Portuguese hospitals. In this article I revise bioethical publications and decree-laws enabling an informed appraisal of the anxieties and prospects for the implementation of the clinical trials Directive in Portugal. This article also places the European Directive in the field of sociology of bioethics, arguing that Portuguese bioethical institutions differ from those of the US, and also from Northern European counterparts. The main divergence is that those people in Portugal who claim expertise in 'legal' bioethics do not dominate either the bureaucratic structure of research or ethics committees for health. Even experts in the applied ethics field now claim that 'professional bioethicists do not exist'. The recent creation of a national Ethics Committee for Clinical Investigation (CEIC) in line with the European Directive on Good Clinical Practice (GCP) will not change the present imbalance between different professional jurisdictions in the national bioethical debate in Portugal.

  17. Portugal takes step back on abortion legalization.

    Science.gov (United States)

    1998-07-01

    According to international press reports, a law that would have allowed Portuguese women abortions through the 10th week of pregnancy and into the 16th week if their physical or mental health was at risk has been rescinded after a referendum to determine the statute's future was voided because of low voter turnout. Passed in February, the law was a liberalization of Portugal's strict anti-abortion laws, which ban all abortions except for narrowly defined medical reasons or in the case of rape (and those are permitted only until the 12th week of pregnancy). Because the issue is such a controversial one, politicians had turned to a national referendum asking Portuguese voters to overturn or ratify the new law. The referendum was the first in the country since the end of its right-wing dictatorship in 1974, and 50% participation was required. Only 31.5% of the country's 8.5 million eligible voters went to the polls on June 28. Of those voting, 50.9% voted against the liberalized new legislation. Sunny weather and World Cup soccer matches were both pointed to as reasons for the low turnout. Officials estimate there are some 20,000 illegal abortions annually in Portugal. Abortion-rights activists in the mostly Roman-Catholic country say hospitals see roughly 10,000 women a year suffering from complications from illegal abortions, and that at least 800 women die each year from the procedure. In the next day's Diario de Noticias, a daily paper in Portugal, the entire front page was filled with a giant question mark. "What now, lawmakers?" the headline read. full text

  18. Paclitaxel-loaded redox-sensitive nanoparticles based on hyaluronic acid-vitamin E succinate conjugates for improved lung cancer treatment.

    Science.gov (United States)

    Song, Yu; Cai, Han; Yin, Tingjie; Huo, Meirong; Ma, Ping; Zhou, Jianping; Lai, Wenfang

    2018-01-01

    Lung cancer is the primary cause of cancer-related death worldwide. A redox-sensitive nanocarrier system was developed for tumor-targeted drug delivery and sufficient drug release of the chemotherapeutic agent paclitaxel (PTX) for improved lung cancer treatment. The redox-sensitive nanocarrier system constructed from a hyaluronic acid-disulfide-vitamin E succinate (HA-SS-VES, HSV) conjugate was synthesized and PTX was loaded in the delivery system. The physicochemical properties of the HSV nanoparticles were characterized. The redox-sensitivity, tumor-targeting and intracellular drug release capability of the HSV nanoparticles were evaluated. Furthermore, in vitro and in vivo antitumor activity of the PTX-loaded HSV nanoparticles was investigated in a CD44 over-expressed A549 tumor model. This HSV conjugate was successfully synthesized and self-assembled to form nanoparticles in aqueous condition with a low critical micelle concentration of 36.3 μg mL -1 . Free PTX was successfully entrapped into the HSV nanoparticles with a high drug loading of 33.5% (w/w) and an entrapment efficiency of 90.6%. Moreover, the redox-sensitivity of the HSV nanoparticles was confirmed by particle size change of the nanoparticles along with in vitro release profiles in different reducing environment. In addition, the HA-receptor mediated endocytosis and the potency of redox-sensitivity for intracellular drug delivery were further verified by flow cytometry and confocal laser scanning microscopic analysis. The antitumor activity results showed that compared to redox-insensitive nanoparticles and Taxol ® , PTX-loaded redox-sensitive nanoparticles exhibited much greater in vitro cytotoxicity and apoptosis-inducing ability against CD44 over-expressed A549 tumor cells. In vivo, the PTX-loaded HSV nanoparticles possessed much higher antitumor efficacy in an A549 mouse xenograft model and demonstrated improved safety profile. In summary, our PTX-loaded redox-sensitive HSV nanoparticles

  19. Molecular approach to characterize ectomycorrhizae fungi from Mediterranean pine stands in Portugal

    Directory of Open Access Journals (Sweden)

    Carla Ragonezi

    2013-01-01

    Full Text Available Stone pine (Pinus pinea L., like other conifers, forms ectomycorrhizas (ECM, which have beneficial impact on plant growth in natural environments and forest ecosystems. An in vitro co-culture of stone pine microshoots with pure mycelia of isolated ECM sporocarps was used to overcome the root growth cessation not only in vitro but also to improve root development during acclimation phase. Pisolithus arhizus (Scop. Rauschert and Lactarius deliciosus (L. ex Fr. S.F. Gray fungi, were collected, pure cultured and used in in vitro co-culture with stone pine microshoots. Samples of P. arhizus and L. deliciosus for the in vitro co-cultures were collected from the pine stands southwest Portugal. The in situ characterization was based on their morphotypes. To confirm the identity of the collected material, ITS amplification was applied using the pure cultures derived from the sporocarps. Additionally, a molecular profile using PCR based genomic fingerprinting comparison was executed with other genera of Basidiomycetes and Ascomycetes. Our results showed the effectiveness of the techniques used to amplify DNA polymorphic sequences, which enhances the characterization of the genetic profile of ECM fungi and also provides an option to verify the fungus identity at any stage of plant mycorrhization.

  20. Molecular approach to characterize ectomycorrhizae fungi from Mediterranean pine stands in Portugal

    Science.gov (United States)

    Ragonezi, Carla; Caldeira, A. Teresa; Martins, M. Rosário; Salvador, Cátia; Santos-Silva, Celeste; Ganhão, Elsa; Klimaszewska, Krystyna; Zavattieri, Amely

    2013-01-01

    Stone pine (Pinus pinea L.), like other conifers, forms ectomycorrhizas (ECM), which have beneficial impact on plant growth in natural environments and forest ecosystems. An in vitro co-culture of stone pine microshoots with pure mycelia of isolated ECM sporocarps was used to overcome the root growth cessation not only in vitro but also to improve root development during acclimation phase. Pisolithus arhizus (Scop.) Rauschert and Lactarius deliciosus (L. ex Fr.) S.F. Gray fungi, were collected, pure cultured and used in in vitro co-culture with stone pine microshoots. Samples of P. arhizus and L. deliciosus for the in vitro co-cultures were collected from the pine stands southwest Portugal. The in situ characterization was based on their morphotypes. To confirm the identity of the collected material, ITS amplification was applied using the pure cultures derived from the sporocarps. Additionally, a molecular profile using PCR based genomic fingerprinting comparison was executed with other genera of Basidiomycetes and Ascomycetes. Our results showed the effectiveness of the techniques used to amplify DNA polymorphic sequences, which enhances the characterization of the genetic profile of ECM fungi and also provides an option to verify the fungus identity at any stage of plant mycorrhization. PMID:24294266

  1. Electricity consumption and economic growth nexus in Portugal using cointegration and causality approaches

    International Nuclear Information System (INIS)

    Shahbaz, Muhammad; Tang, Chor Foon; Shahbaz Shabbir, Muhammad

    2011-01-01

    The aim of this paper is to re-examine the relationship between electricity consumption, economic growth, and employment in Portugal using the cointegration and Granger causality frameworks. This study covers the sample period from 1971 to 2009. We examine the presence of a long-run equilibrium relationship using the bounds testing approach to cointegration within the Unrestricted Error-Correction Model (UECM). Moreover, we examine the direction of causality between electricity consumption, economic growth, and employment in Portugal using the Granger causality test within the Vector Error-Correction Model (VECM). As a summary of the empirical findings, we find that electricity consumption, economic growth, and employment in Portugal are cointegrated and there is bi-directional Granger causality between the three variables in the long-run. With the exception of the Granger causality between electricity consumption and economic growth, the rest of the variables are also bi-directional Granger causality in the short-run. Furthermore, we find that there is unidirectional Granger causality running from economic growth to electricity consumption, but no evidence of reversal causality. - Highlights: → We re-examine the relationship between electricity consumption, economic growth, and employment in Portugal. → The electricity consumption and economic growth is causing each other in the long-run. → In the short-run, economic growth Granger-cause electricity consumption, but no evidence of reversal causality. → Energy conservation policy will deteriorate the process of economic growth in the long-run. → Portugal should increase investment on R and D to design new energy savings technology.

  2. Etudes sur le Portugal au Temps de l'Humanisme

    Directory of Open Access Journals (Sweden)

    J. Cruz Costa

    1953-06-01

    Full Text Available BATAILLON (Marcel. — Etudes sur le Portugal au Temps de l'Humanisme.  Acta Universitatis Conimbrigencis, 1952, 309 pp. (Primeiro Parágrafo do Artigo O Prof. Marcel Bataillon, erudito dos mais inteligentes da França atual, autor de uma obra que é hoje impr:scindível para quem pretenda estudar o humanismo renascentista na Espanha ou em Portugal, diríamos melhor, talvez: para quem pretenda estudar o Humanismo e a Renascença, — acaba de publicar, na coleção Acta Universitatis Conimbrigencis, êste volume no qual reune alguns trabalhos da mais alta importância para o conhecimento de muitos aspectos da vida espiritual portuguêsa do século XVI.

  3. Primeras evidencias de arte mueble paleolítico en el sur de Portugal

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    Simón Vallejo, María D.

    2012-06-01

    Full Text Available This paper presents the first evidence for Palaeolithic portable art in Southern Portugal. This include two plaques, dated between 20,500 and 19,500 BP from Solutrean levels from the site of Vale Boi, Western Algarve (Portugal. One of the pieces is a small engraved schist plaque (14,6 × 8,1 mm with abstract lines on one side. The other artefact is an 8 × 5 cm schist plaque. One side is an oxide natural deposit, used to produce dye; the other side has three aurochs and a probable cervid. Stilistic information and the engraving sequence indicate probably production by a single artist. The stylistic characteristics are in full agreement withi those from late Gravettian and early Solutrean art known from Valencia, Andalucia (Spain and the Côa valley (Portugal, thus confirming the absolute AMS dates from the Vale Boi Levels.

    En este trabajo presentamos la primera evidencia de arte mueble paleolítico en el sur de Portugal: dos plaquetas de pizarra procedentes de niveles solutrenses del yacimiento de Vale Boi, zona occidental del Algarve (Portugal. La primera de las piezas es una pequeña placa (14,6 × 8,1 mm que presenta sobre una de sus caras un ideomorfo grabado. La segunda (8 × 5 cm cuenta con una superficie ocupada por óxido de hierro natural de color amarillento, tiene claros indicios de extracción de mineral para producir colorantes. En la superficie opuesta han sido grabados tres uros y una posible cierva. El estilo y secuencia de los grabados apuntan a un solo artista. Las características estilísticas de los zoomorfos concuerdan bien con los rasgos comunes del arte del ciclo Gravetiense final y Solutrense antiguo del País Valenciano, Andalucía y Valle de Côa (Portugal. Esta afinidad sintoniza asimismo con las fechas AMS de los niveles solutrenses de Vale Boi, datados entre ca. 20.500 y 19.500 BP.

  4. Migration, Quality of Life And Health of Brazilian Immigrants in Portugal

    Directory of Open Access Journals (Sweden)

    Eliany Nazaré Oliveira

    2017-05-01

    Full Text Available Background: Immigrants face many challenges when settling in a foreign country, numerous factors influence this immigrant experience including the resources they bring with them and those they find in the host society. The literature has indicated that a significant number of individuals migrate in search of a better quality of life. In this context, the objective of the study was to analyze the quality of life and health of Brazilian immigrants living in Portugal, using the "Medical Outcomes Study: 36-Item Short Form Survey" (SF-36. Methods and Results: A cross-sectional study with a quantitative approach developed under the project titled: Health status and quality of life of Brazilian immigrants in Portugal conducted in the first half of 2016, with 682 Brazilian immigrant women over 18 living in Portugal. This study adopted as reference SF-36, a generic instrument for the evaluation of Quality of Life. It can be affirmed that the quality of life and health of Brazilian immigrants living in Portugal is good, since all dimensions presented values above 50%. It was evidenced that Brazilian immigrants who live alone have lower levels of quality of life and health than those who live with someone and, that Brazilian immigrants who are unemployed, have low levels of quality of life and health compared to those who are in another employment situation, and Brazilian immigrants entering the labor market with a workload of more than 40 hours per week present similar levels of quality of life and health compared to those who work fewer hours. Conclusion: In general, one can affirm that the quality of life and health of Brazilian immigrants living in Portugal is good, but due to the particularities of the migration process in the current political and international context, a systematic monitoring of living conditions and health of this population is necessary. Keywords: Emigrants and Immigrants; Quality of life; Women, Mental health

  5. Psychosocial concomitants of loneliness among students of Cape Verde and Portugal.

    Science.gov (United States)

    Neto, F; Barros, J

    2000-09-01

    This research is an examination of the relationship between loneliness and a number of psychosocial variables (e.g., affective state, cultural issues, gender, age) among adolescents and young adults from Cape Verde and Portugal. Two studies are presented. The participants in the first study were 285 adolescents from Cape Verde and 202 from Portugal, and in the second study there were 134 college students from Cape Verde and 112 from Portugal. The following instruments were administered to all the participants in both studies: The Revised UCLA Loneliness Scale (D. Russell, L. Peplau, & C. Cutrona, 1980), the Neuroticism Scale (J. Barros, 1999), the Optimism Scale (J. Barros, 1998), the Social Anxiety subscale (A. Fenigstein, M. Scheier, & A. Buss, 1975), and the Satisfaction With Life Scale (E. Diener, R. Emmons, R. Larsen, & S. Griffin, 1985). No ethnic or gender differences were found for loneliness between the two groups. For both groups, the most prominent predictors of loneliness were neuroticism and dissatisfaction with life. However, as expected, the adolescent group recorded higher scores for loneliness than did the college students.

  6. Evolução da mortalidade por cancro do pulmão em Portugal (1955-2005 Trends in lung cancer mortality in Portugal (1955-2005

    Directory of Open Access Journals (Sweden)

    Luís Alves

    2009-08-01

    Full Text Available Introdução: A prevalência de fumadores tem diminuído na Europa Ocidental, observando-se já o declínio da mortalidade por cancro do pulmão. Contudo, até 1998 não se observava ainda um decréscimo da frequência deste cancro em Portugal. Objectivo: Descrever a tendência secular da mortalidade por cancro do pulmão em Portugal. Métodos: As taxas de mortalidade por cancro do pulmão (ICD10:C33-34 em Portugal, entre 1955 e 2005, por sexo e grupo etário (5 anos de amplitude, obtiveram-se através da Organização Mundial de Saúde e do Instituto Nacional de Estatística. Calcularam-se taxas de mortalidade padronizadas (método directo, população mundial, para os grupos etários 35-74/35-44/45-54/55-64/65-74 anos. Realizou-se uma regressão joinpoint para calcular a variação anual percentual (VA% da mortalidade e identificar eventuais pontos de inflexão. Resultados: Entre 1955 e 2005, em homens dos 35 aos 74 anos, observou-se uma estabilização da mortalidade por cancro do pulmão, variando 3,77%/ano (intervalo de confiança a 95% [IC95%]: 3,53; 4,01 entre 1955 e 1986 e -0,15%/ano (IC95%: -0,99; 0,69 entre 1996 e 2005. Observaram-se estimativas pontuais da VA% negativas (não significativamente inferiores a zero nas tendências mais recentes de todos os grupos etários, excepto no grupo 45-54 anos, onde apenas se verificou uma desaceleração da VA% desde 1981. Em mulheres entre 35 e 74 anos, a mortalidade aumentou 1,60%/ano (IC95%: 1,40; 1,77 entre 1955 e 2005. Conclusão: Observou-se uma estabilização das taxas de mortalidade por cancro do pulmão nos homens, enquanto nas mulheres esta aumentou de forma constante. Estes resultados colocam Portugal no final do terceiro estádio da epidemia tabágica.Introduction: While the rate of smoking and lung cancer mortality has been decreasing in western Europe, there was no decline in lung cancer mortality in Portugal until 1998. Aim: To describe lung cancer mortality trends in Portugal

  7. [Cerebrovascular mortality in Portugal: are we overemphasizing hypertension and neglecting atrial fibrillation?].

    Science.gov (United States)

    Providência, Rui; Gonçalves, Lino; Ferreira, Maria João

    2013-11-01

    Cerebrovascular disease has long been the leading cause of death in Portugal. Despite improvements in the treatment of hypertension and the resulting decrease in associated mortality, the progressive aging of the population and increased prevalence of atrial fibrillation have prevented the incidence of stroke from falling as much as desired. The authors review the evidence on the situation in Portugal and propose an intervention plan. Copyright © 2013 Sociedade Portuguesa de Cardiologia. Published by Elsevier España. All rights reserved.

  8. Finance and economic and social reproduction: prospects for financialised futures in Portugal

    OpenAIRE

    Rodrigues, João; Santos, Ana C.; Teles, Nuno

    2016-01-01

    Portugal is a semi-peripheral country within the EU that has partially followed similar processes as those of most financialised core countries, and that has been particularly hard-hit by the GFC. This paper reflects on the factors that have shaped economic and social reproduction in Portugal, drawing on previous research examining the involvement of households with finance and the systems of provision for housing, pensions and water conducted for WP5 and WP8 of FESSUD. Based on the Portugues...

  9. International Uranium Resources Evaluation Project (IUREP) orientation phase mission summary report: Portugal

    International Nuclear Information System (INIS)

    1985-01-01

    A report has recently been published which describes the findings of the International Uranium Resources Evaluation Project (IUREP) mission to Portugal. The IUREP Orientation Phase mission to Portugal estimates that the Speculative Resources of that country fall within the range 20,000 to 80,000 tonnes uranium. The majority of this potential is expected to be located in intergranitic vein deposits and in pre-Ordovician schists, but other favourable geological environments include episyenites and Meso-Cainozoic continental sediments. The mission recommends that approximately US$25 million be spent on exploration in Portugal over the next 10 years. The majority of this ($18 million) would be spent on drilling, with a further $7 million on surface surveys and airborne radiometric surveys. It is the opinion of the IUREP Orientation Phase Mission that the considerable funding required for the outlined programme would most suitably be realized by inviting national or foreign commercial organisations to participate in the exploration effort under a partnership or shared production arrangements. (author)

  10. Atmospheric circulation classification comparison based on wildfires in Portugal

    Science.gov (United States)

    Pereira, M. G.; Trigo, R. M.

    2009-04-01

    Atmospheric circulation classifications are not a simple description of atmospheric states but a tool to understand and interpret the atmospheric processes and to model the relation between atmospheric circulation and surface climate and other related variables (Radan Huth et al., 2008). Classifications were initially developed with weather forecasting purposes, however with the progress in computer processing capability, new and more robust objective methods were developed and applied to large datasets prompting atmospheric circulation classification methods to one of the most important fields in synoptic and statistical climatology. Classification studies have been extensively used in climate change studies (e.g. reconstructed past climates, recent observed changes and future climates), in bioclimatological research (e.g. relating human mortality to climatic factors) and in a wide variety of synoptic climatological applications (e.g. comparison between datasets, air pollution, snow avalanches, wine quality, fish captures and forest fires). Likewise, atmospheric circulation classifications are important for the study of the role of weather in wildfire occurrence in Portugal because the daily synoptic variability is the most important driver of local weather conditions (Pereira et al., 2005). In particular, the objective classification scheme developed by Trigo and DaCamara (2000) to classify the atmospheric circulation affecting Portugal have proved to be quite useful in discriminating the occurrence and development of wildfires as well as the distribution over Portugal of surface climatic variables with impact in wildfire activity such as maximum and minimum temperature and precipitation. This work aims to present: (i) an overview the existing circulation classification for the Iberian Peninsula, and (ii) the results of a comparison study between these atmospheric circulation classifications based on its relation with wildfires and relevant meteorological

  11. La inmigración brasileña en Portugal y España: ¿sistema migratorio ibérico? (Brazilian immigration in Portugal and Spain: Iberian immigration system?

    Directory of Open Access Journals (Sweden)

    Padilla, Beatriz

    2010-06-01

    Full Text Available Resumen: El objetivo de este artículo es ofrecer un análisis comparativo de la migración brasileña en España y Portugal a través de su contextualización en la emigración brasileña internacional reciente, la descripción de las características básicas y de los principales perfiles de esta población y del estudio de las motivaciones de la emigración y de la elección del país de destino. El estudio se basa fundamentalmente en las investigaciones llevadas a cabo por las autoras en el contexto portugués, español y brasileño desde una perspectiva metodológica cualitativa. Los resultados de la investigación señalan la presencia de similitudes y divergencias en los dos contextos de recepción de la migración brasileña. Sin embargo, el predominio de los paralelismos nos lleva a sugerir la existencia de una migración brasileña ibérica.Abstract: The aim of this article is to carry out a comparative analysis of Brazilian migration to Spain and Portugal, by providing a contextualization within the recent Brazilian international emigration flows, and a description of its basic features and main profiles of the population; and by offering explanations about the motivations for migration and about the selection of the country of destination. The study is mainly based on qualitative research carried out by the authors in the Portuguese, Spanish and Brazilian contexts. Results highlight similarities and differences in both contexts of reception of Brazilian immigration, however the prevalence of parallelisms suggests the existence of an Iberian Brazilian migration system.

  12. Crise econômica e retorno dos imigrantes brasileiros em Portugal

    Directory of Open Access Journals (Sweden)

    Carolina Nunan

    Full Text Available A crise econômica internacional desencadeada em 2008 produziu enormes efeitos sobre as migrações mundiais. Alguns estudos têm sido dedicados a esta temática. O objetivo deste artigo é refletir e discutir sobre a existência de um possível fluxo de retorno dos imigrantes brasileiros em Portugal ao país de origem. Os resultados desta investigação apontam para uma desaceleração do fluxo de entrada em Portugal, uma propensão significativa ao retorno, mas um volume efetivo de retorno inferior ao que seria teoricamente de esperar.

  13. Energy taxation in Southern Europe: The case of Portugal

    International Nuclear Information System (INIS)

    Modesto, L.

    1993-01-01

    It is investigated whether or not the imposition of a common EC energy tax will penalize more the poorer Southern European economies and if this will harm convergence at the EC level. The existing studies and empirical evidence are briefly surveyed. Then the results obtained when using the macroeconometric HERMES models to stimulate the introduction of an energy tax are exploited. The conclusions, however, have limited value, since the authors only have HERMES results for one Southern European economy: Portugal. Finally, the convergence in Europe and the effects of energy taxation on convergence are investigated. It is concluded that energy taxation will harm growth all over the EC, penalizing more one of the less developed countries (in this case Portugal), and having most probably adverse effects on convergence. 5 figs., 6 tabs., 22 refs

  14. Las relaciones financieras entre España y Portugal, 1563-1580

    Directory of Open Access Journals (Sweden)

    Óscar LUCAS VILLANUEVA

    2009-12-01

    Full Text Available RESUMEN: Las economías de Castilla y Portugal durante la segunda mitad del siglo XVI estaban estrechamente ligadas por vínculos financieros. Un espacio económico en desarrollo, el del Atlántico septentrional, comprendía ambos territorios y se organizaba a partir de los grandes centros feriales de Amberes, Lyon y Medina. El gran tráfico mercantil transoceánico se hacía presente en este escenario europeo gracias a la intervención de España y Portugal, pero con papeles bien distintos: España, incontinente, drenando el oro y la plata americanos hacia Europa, Portugal suministrando las apreciadas mercancías orientales. Las ferias de Medina del Campo y los mercaderes castellanos como Simón Ruiz se convierten en colaboradores necesarios de los mercaderes portugueses, pues a través de éstos negociaban los reembolsos o inversiones financieras en las plazas europeas; sin embargo, para ello era preciso un buen conocimiento de los negocios cambiarlos y su oportunidad, atendiendo a la cotización de las distintas monedas y a demanda de dinero en las ferias europeas. De la mano del mercader medinense entran los lisboetas en las grandes finanzas y la concertación de asientos con la Corona, aunque tal vez sin la pujanza que Felipe II hubiese deseado.ABSTRACT: The correspondence studied shows the importance that had, for this period of time (1563-1580, the relationship between Castille and Portugal. The vigorous economic space of the Northern Atlantic, the space in which were inscribed both territories, was organised from the three great market centres of Amberes, Lyon and Medina del Campo. The big transoceanic commercial trade was present in this European scenery thanks to the supervision of Spain an Portugal, but playing a very different role: Spain, draining gold and silver to Europe; and Portugal, supplying the appreciated oriental goods. The fairs of Medina and the Castilian merchants, like Simon Ruiz, were converted in necessary

  15. The Afrotropical Miomantiscaffra Saussure 1871 and Miomantispaykullii Stal 1871: first records of alien mantid species in Portugal and Europe, with an updated checklist of Mantodea in Portugal (Insecta: Mantodea).

    Science.gov (United States)

    Marabuto, Eduardo

    2014-01-01

    The recent growing interest on the Mantodea fauna of southern Europe and Portugal in particular, has enabled the discovery of two geographically separated populations of hitherto unknown species in Europe. Analysis of specimens shows that they belong to two Afrotropical mantids: Miomantiscaffra Saussure, 1871 and Miomantispaykullii Stal, 1871, thus raising the number of known species in Europe to 39 and in Portugal to 11. While these are remarkable findings, they also represent the first alien mantis species recorded from this continent. As yet, these species appear to be confined to artificial humanised gardened areas but call for more attention to the problem of biological invasions and the need for better bio-security measures for the conservation of natural ecosystems. In the absence of recent revisionary work on the Mantodea of Portugal and given the need to provide an accessible identification tool, both a checklist and a key to species are provided for all species in the country.

  16. IL-1RN VNTR polymorphism as a susceptibility marker for nasopharyngeal carcinoma in Portugal.

    Science.gov (United States)

    Sousa, Hugo; Breda, Eduardo; Santos, Alexandra M; Catarino, Raquel; Pinto, Daniela; Canedo, Paulo; Machado, José Carlos; Medeiros, Rui

    2013-08-01

    Nasopharyngeal carcinoma (NPC) is a rare malignancy in Western countries that is widely associated with the infection by Epstein-Barr virus (EBV). Several studies have showed that a common allele (allele 2) of the 86-bp variable number of tandem repeats (VNTR) polymorphism within intron 2 of the interleukin 1 receptor antagonist (IL-1RN) gene is associated with several disorders, including viral-associated cancers. We have developed a hospital-based case-control study to characterise the role of the IL-1RN 86-bp VNTR polymorphism in the development of NPC with 112 patients with the disease and 433 healthy individuals from the northern region of Portugal. IL-1RN genotypes were combined according to the number of repeats: allele 2 (A2), the short allele that corresponds to two repeats, and L, the long allele that corresponds to three or more repeats. Our study revealed that 31.2% of NPC patients were IL-1RN A2*A2, compared with 9.7% observed in the control group. The statistical analysis revealed that IL-1RN*A2 homozygosity for the A2 allele was associated with a fourfold increased risk for NPC development (pVNTR in NPC development in Portugal. Our study indicates IL-1RN*A2 homozygosity as a significant risk marker in our population and that it should be further investigated for the potential role in the definition of a susceptibility profile for NPC onset. Copyright © 2013 Elsevier Ltd. All rights reserved.

  17. Migration Flow and Its Impact on Tuberculosis Notification in Portugal.

    Science.gov (United States)

    Dias, Ana; Gaio, Rita; Sousa, Pedro; Gomes, Marta; Oliveira, Olena; Duarte, Raquel

    2018-01-01

    Tuberculosis notification in Portugal has decreased in the last few years. As a consequence of the economic crisis, emigration has increased and immigration has decreased. Immigrants are a risk group for tuberculosis. Most emigrants are 20-44 years old and belong to the age group most affected by tuberculosis. To describe the decrease in tuberculosis notification in Portugal over the last years from a demographical point of view. Mathematical analysis was performed to quantify the effect of the migration movements (separately and simultaneously) on tuberculosis notification in Portugal from 2008 to 2014. We calculated the estimated tuberculosis notification for each year during the period of study: 1) fixing immigration rate and tuberculosis rate in immigrants at 2008 values; 2) fixing emigration rate and tuberculosis rate in emigrants at 2008 values; 3) fixing both phenomenons at 2008 values. The differences between the observed and the estimated numbers were small (≤0.5 cases/100000 inhabitants). Impact of the migration movements on tuberculosis notification rate does not seem to be significant when analyzed for each phenomenon individually and simultaneously, by our model. This might mean that we have to concentrate our efforts in other risk factors for tuberculosis. Copyright © 2017 SEPAR. Publicado por Elsevier España, S.L.U. All rights reserved.

  18. Education, State, and Society in Portugal, 1926-1981.

    Science.gov (United States)

    Stoer, Stephen R.; Dale, Roger

    1987-01-01

    Examines the relationship between the state and education in Portugal during periods of modernization, dictatorship, revolution, and democratization from 1926-81. Discusses the role of education, problems faced by education and other ideological systems, and the relationship between education and national development in each historical period. (SV)

  19. I-V Characteristics of PtxCo1−x (x = 0.2, 0.5, and 0.7 Thin Films

    Directory of Open Access Journals (Sweden)

    M. Erkovan

    2013-01-01

    Full Text Available Three different chemical ratios of PtxCo1−x thin films were grown on p-type native oxide Si (100 by Magneto Sputtering System with cosputtering technique at 350°C temperature to investigate electrical prosperities. X-ray photoelectron spectroscopy analysis technique was used to specify chemical ratios of these films. The current-voltage (I-V measurements of metal-semiconductor (MS Schottky diodes were carried out at room temperature. From the I-V analysis of the samples, ideality factor (n, barrier height (ϕ, and contact resistance values were determined by using thermionic emission (TE theory. Some important parameters such as barrier height, ideality factor, and serial resistance were calculated from the I-V characteristics based on thermionic emission mechanism. The ideality factors of the samples were not much greater than unity, and the serial resistances of the samples were also very low.

  20. Critical analysis of documentary sources for Historical Climatology of Northern Portugal (17th-19th centuries)

    Science.gov (United States)

    Amorim, Inês; Sousa Silva, Luís; Garcia, João Carlos

    2017-04-01

    Critical analysis of documentary sources for Historical Climatology of Northern Portugal (17th-19th centuries) Inês Amorim CITCEM, Department of History, Political and International Studies, U. of Porto, Portugal. Luís Sousa Silva CITCEM, PhD Fellowship - FCT. João Carlos Garcia CIUHCT, Geography Department, U. of Porto, Portugal. The first major national project on Historical Climatology in Portugal, called "KLIMHIST: Reconstruction and model simulations of past climate in Portugal using documentary and early instrumental sources (17th-19th centuries)", ended in September 2015, coordinated by Maria João Alcoforado. This project began in March 2012 and counted on an interdisciplinary team of researchers from four Portuguese institutions (Centre of Geographical Studies, University of Trás-os-Montes and Alto Douro, University of Porto, and University of Évora), from different fields of knowledge (Geography, History, Biology, Climatology and Meteorology). The team networked and collaborated with other international research groups on Climate Change and Historical Climatology, resulting in several publications. This project aimed to reconstruct thermal and rainfall patterns in Portugal between the 17th and 19th centuries, as well as identify the main hydrometeorological extremes that occurred over that period. The basic methodology consisted in combining information from different types of anthropogenic sources (descriptive and instrumental) and natural sources (tree rings and geothermal holes), so as to develop climate change models of the past. The data collected were stored in a digital database, which can be searched by source, date, location and type of event. This database, which will be made publically available soon, contains about 3500 weather/climate-related records, which have begun to be studied, processed and published. Following this seminal project, other initiatives have taken place in Portugal in the area of Historical Climatology, namely a Ph

  1. Consideration on the technical service quality and the Portugal situation; Consideracoes sobre a qualidade tecnica de servico e caracterizacao da situacao em Portugal

    Energy Technology Data Exchange (ETDEWEB)

    Santana, J.; Afonso, Jose [Entidade Reguladora do Sector Electrico (ERSE), XX (Portugal)

    1999-07-01

    This paper presents some considerations on the technical quality of power supply for the consumption and, for the specific characterization of the Portugal electric sector, a summary analysis of the energy production, transport and distribution activities.

  2. Monitores de diagnóstico em Mamografia : (Os 5MP em Portugal)

    OpenAIRE

    Timóteo, Maria Teresa

    2012-01-01

    O carcinoma da mama é o mais comum nas mulheres, em Portugal morrem cerca de 1500 mulheres por ano devido a esta patologia. Serviu o presente estudo para investigar se os Hospitais da Região de Lisboa e Vale do Tejo estão equipados, com monitores de diagnóstico em mamografia, que correspondam com as guidelines europeias. O serviço de Mamografia, em Portugal rege-se por estas guidelines, em que é referenciado que para um correcto diagnóstico, com toda a sensibilidade e especific...

  3. Ordens militares de cavalaria de Portugal

    Directory of Open Access Journals (Sweden)

    Álvaro da Veiga Coimbra

    1963-03-01

    Full Text Available Falar nas Ordens Militares de Cavalaria de Portugal, é ter presente a própria história da fundação da monarquia e de re-cuperação territorial e também dos descobrimentos de novos mundos para a civilização. Aos seus cavaleiros couberam no cenário das lutas sangrentas e constantes da dinastia afonsina, os grandes postos da vanguarda.

  4. History of Astronomy in Portugal: Theories, Institutions and Practices

    Science.gov (United States)

    Saraiva, Luis

    2014-01-01

    In Portugal, throughout its history, astronomy was developed in the context of the mathematical sciences. During the times of Portugal's Maritime Discoveries, astronomical navigation was based on spherical trigonometry, and therefore it was the mathematicians who taught astronomy to the pilots. During the 17th century, basic notions of astronomy were taught in mathematical courses in the University and in the main Jesuit colleges. This tradition continued in the 18th century, so it is no wonder that one of the most influent Portuguese astronomers during this period was the mathematician José Monteiro da Rocha. During the 19th century the new centres of science teaching, as the Polytechnic School in Lisbon, or the Polytechnic Academy in Oporto, developed astronomy teaching and research in the context of the mathematics subjects. The inheritors of these 19th century institutions, respectively the Faculties of Sciences of Lisbon and Oporto, upheld this tradition until the final decades of 20th century and continued to consider astronomy as a subject to be taught in their mathematics departments. This Meeting aims at outlining several perspectives on the history of astronomy in Portugal, particularly analysing its ties with mathematical sciences and astronomy applications. The Meeting is organised by the Museum of Science of the University of Lisbon (MCUL) with CMAF, CMUC, CMUP and the CIUHCT, and is included in CIM events. It is integrated in the commemorations of the International Year of Astronomy (IYA2009).

  5. The Policy Gap. Global Mental Health in a Semi-Peripheral Country (Portugal, 1998-2016

    Directory of Open Access Journals (Sweden)

    Tiago Pires Marques

    2017-07-01

    Full Text Available This paper analyzes the impact of the hegemonic paradigm of global mental health (GMH on Portugal. We specifically argue that GMH in Portugal has effected a change of priorities in health policies, favoring the prevention and treatment of common mental disorders to the detriment of the deinstitutionalizing process. Diffused through the media, this model has negative effects, such as the medicalization of social suffering, the reorganization of mental health policy areas according to utilitarian criteria, and the risk of greater invisibility of users with serious psychiatric diagnoses. However, the GMH approach, bringing to the frontline the impact of all social policies on mental health, represents a new opportunity to politically address social suffering. Characterized as a semi-peripheral country, Portugal may be representative of observable trends in similar countries.

  6. Early Childhood Education and Care Policy in Portugal = A Educacao Pre-Escolar e os Cuidados para a Infancia em Portugal.

    Science.gov (United States)

    Ministry of Education, Lisbon (Portugal).

    Based on the view that the rapid expansion and development of preschool education requires careful scrutiny of both educational policy and practices, this book presents information on current early childhood education and care policy in Portugal. Section 1 of the book provides a historical framework for the development of early childhood education…

  7. Cutaneous leishmaniosis in a horse from northern Portugal

    NARCIS (Netherlands)

    Gama, Adelina; Elias, Joana; Ribeiro, Ana J.; Alegria, Nuno; Schallig, Henk D. F. H.; Silva, Filipe; Santarém, Nuno; Cardoso, Luís; Cotovio, Mário

    2014-01-01

    The first case of cutaneous leishmaniosis in a horse from the north of Portugal, with a 1.5 cm in diameter ulcerated nodular lesion on the left face, is reported. The skin nodule was surgically excised and assessed by histopathology, including an immunohistochemistiy method applied for the first

  8. Flora-On: Occurrence data of the vascular flora of mainland Portugal.

    Science.gov (United States)

    Pereira, Ana Júlia; Francisco, Ana; Porto, Miguel

    2016-01-01

    The Flora-On dataset currently includes 253,310 occurrence records for the class Embryopsidae (vascular plants), comprising data collated via the platform http://flora-on.pt/ relating to observation records of vascular plants across mainland Portugal. Observations are uploaded directly to the database primarily by experienced botanists and naturalists, typically on a weekly basis, and consist of geo-referenced data points for species (or infraspecific taxa) along with their date of observation and phenological state. The Flora-On project aims to compile and make publicly accessible chorological, ecological, morphological and photographic information for the entire vascular flora of Portugal. The project's website offers powerful query and visualization capabilities, of which we highlight the probabilistic bioclimatic and phenological queries which operate based on the empirical density distributions of species in those variables. Flora-On was created and continues to be maintained by volunteers who are Associate members of Sociedade Portuguesa de Botânica (Botanical Society of Portugal). Given its focus on research-grade and current data, the Flora-On project represents a significant contribution to the knowledge of the present distribution and status of the Portuguese flora.

  9. Post-fire vegetation recovery in Portugal based ewline on spot/vegetation data

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    C. Gouveia

    2010-04-01

    Full Text Available A procedure is presented that allows identifying large burned scars and the monitoring of vegetation recovery in the years following major fire episodes. The procedure relies on 10-day fields of Maximum Value Composites of Normalized Difference Vegetation Index (MVC-NDVI, with a 1 km×1 km spatial resolution obtained from the VEGETATION instrument. The identification of fire scars during the extremely severe 2003 fire season is performed based on cluster analysis of NDVI anomalies that persist during the vegetative cycle of the year following the fire event. Two regions containing very large burned scars were selected, located in Central and Southwestern Portugal, respectively, and time series of MVC-NDVI analysed before the fire events took place and throughout the post-fire period. It is shown that post-fire vegetation dynamics in the two selected regions may be characterised based on maps of recovery rates as estimated by fitting a monoparametric model of vegetation recovery to MVC-NDVI data over each burned scar. Results indicated that the recovery process in the region located in Central Portugal is mostly related to fire damage rather than to vegetation density before 2003, whereas the latter seems to have a more prominent role than vegetation conditions after the fire episode, e.g. in the case of the region in Southwestern Portugal. These differences are consistent with the respective predominant types of vegetation. The burned area located in Central Portugal is dominated by Pinus Pinaster whose natural regeneration crucially depends on the destruction of seeds present on the soil surface during the fire, whereas the burned scar in Southwestern Portugal was populated by Eucalyptus that may quickly re-sprout from buds after fire. Besides its simplicity, the monoparametric model of vegetation recovery has the advantage of being easily adapted to other low-resolution satellite data, as well as to other types of vegetation

  10. As viagens ferroviárias em Portugal (1845-1896

    Directory of Open Access Journals (Sweden)

    Hugo Silveira Pereira

    2010-01-01

    Full Text Available Between 1852 and 1893 more than two thousand kilometres of railway were built in Portugal, changing the way people travelled across the Kingdom. Before that, travel only took place by river, by sea along the coast or by land where the lack of obstacles allowed it. This new form of transportation shortened distances and thus gave Portuguese travellers more time. Based on contemporary parliamentary debates, the technical opinions of Portuguese engineering (both manuscript in the records of the Ministry of Public Works and published in technical journals and contemporary fictional literature, this study aims to describe and explain some of the changes to travelling habits in Portugal. We shall see that new habits were brought on by the railway, as well as new concerns and new opportunities, and it quickly became a widely-used public service.

  11. Parasites of marine, freshwater and farmed fishes of Portugal: a review

    Directory of Open Access Journals (Sweden)

    Jorge da Costa Eiras

    Full Text Available Abstract An extensive literature review is made of the parasites in marine and freshwater fish in mainland Portugal, the Portuguese archipelagos of the Azores and Madeira, as well as in farmed fish. The host(s of each parasite species, its location in the host, site of capture of the host, whenever possible, and all the available bibliographic references are described. The economic importance of some parasites and the zoonotic relevance of some parasitic forms are discussed. A general overview of the data is provided, and some research lines are suggested in order to increase and complement the current body of knowledge about the parasites of fish from Portugal.

  12. La Psicología Feminista Crítica en el suroeste semiperiférico europeo: el intrigante caso de Portugal

    OpenAIRE

    Oliveira, J. M.; Neves, S.; Saavedra, L.; Nogueira, C.

    2013-01-01

    Buscamos explorar en este texto los desarrollos en el campo de la psicología crítica feminista en Portugal. Haciendo uso de una narrativa figura-fondo, pondremos en contraste estos desarrollos con la hegemonía de la psicología mainstream en Portugal. En la primera sección, contextualizamos la psicología en Portugal histórica y sociológicamente. En la segunda, exploramos las que están consideradas como las mejores prácticas en la investigación en este campo en Portugal, usando algunos textos m...

  13. How the Gold Standard Functioned in Portugal: An Analysis of Some Macroeconomic Aspects

    OpenAIRE

    António Portugal Duarte; João Sousa Andrade

    2011-01-01

    The purpose of this study is to improve understanding of the gold standard period in Portugal through comparison with other monetary systems that were operated afterwards. Portugal was the first country in Europe to join Great Britain in the gold standard, in 1854, and it adhered to it for quite a long time. The principle of free gold convertibility of the Portuguese currency at a fixed price was abandoned in 1891, even though the classical gold standard as an international monetary system ...

  14. Social housing in Portugal and in the municipality of São Paulo : Comparison of space standards

    NARCIS (Netherlands)

    Costa Branco De Oliveira Pedro, J.A.; Boueri, J.J.

    2010-01-01

    This paper compares the space standards for social housing in Portugal and in São Paulo, and seeks explanations for differences in the socio-economic context of both territories. The Controlled Cost Housing (CCH) in Portugal and the housing built within the program My Home My Life (MHML) in São

  15. Fluency profile: comparison between Brazilian and European Portuguese speakers.

    Science.gov (United States)

    Castro, Blenda Stephanie Alves e; Martins-Reis, Vanessa de Oliveira; Baptista, Ana Catarina; Celeste, Letícia Correa

    2014-01-01

    The purpose of the study was to compare the speech fluency of Brazilian Portuguese speakers with that of European Portuguese speakers. The study participants were 76 individuals of any ethnicity or skin color aged 18-29 years. Of the participants, 38 lived in Brazil and 38 in Portugal. Speech samples from all participants were obtained and analyzed according to the variables of typology and frequency of speech disruptions and speech rate. Descriptive and inferential statistical analyses were performed to assess the association between the fluency profile and linguistic variant variables. We found that the speech rate of European Portuguese speakers was higher than the speech rate of Brazilian Portuguese speakers in words per minute (p=0.004). The qualitative distribution of the typology of common dysfluencies (pPortuguese speakers is not available, speech therapists in Portugal can use the same speech fluency assessment as has been used in Brazil to establish a diagnosis of stuttering, especially in regard to typical and stuttering dysfluencies, with care taken when evaluating the speech rate.

  16. The Tourism Potential of Northern Portugal and Its Relevance for a Regional Branding Strategy

    Directory of Open Access Journals (Sweden)

    Eduardo OLIVEIRA

    2014-12-01

    Full Text Available The purpose of this article is to explore a potential regional branding strategy for the northern part of Portugal, emphasizing the regional tourism potential. Furthermore, it aims to clarify the answers of the following research questions: i is tourism a strategic domain with the potential to integrate a branding strategy at the regional level? ii is a regional branding strategy an engine by which to enable economic and social transformation in the region, thus responding to the contemporary challenges such as weak economic confidence and unemployment? To answer these questions, a content analysis on the policy documents: i Northern Portugal Strategic Guidelines 2014-2020 and ii National Strategic Plan for Tourism 2013-2015 has been performed. In addition, the article details the results of in-depth interviews conducted with two regional entities: i Tourism of Porto and the North of Portugal (TPNP, in charge of national tourism planning and promotion and ii North Regional Coordination and Development Commission (CCDRN, involved in regional planning and development. The findings reinforce the importance of tourism as a strategic domain to boost the economy and create momentum in Northern Portugal. Moreover, tourism is seen by the respondents as a key objective in a regional branding strategy.

  17. Cross-shore flow on the inner-shelf off southwest Portugal

    Science.gov (United States)

    Lamas, L.; Peliz, A.; Oliveira, P.; Dias, J.

    2012-04-01

    Velocity measurements from 4 bottom-mounted ADCP deployments (summers of 2006, 2007, 2008 and 2011) at a 12-m depth site off Sines, Portugal, complemented with time series of winds, waves and tides, are used to study the inner-shelf cross-shore flow dependence on wave, tidal and wind forcings. During these four summers, the dominating winds are from the north (upwelling-favorable), with strong diurnal sea breeze cycle throughout these periods. This quasi-steady wind circulation is sometimes interrupted by short event-like reversals. The observed records were split in different subsets according to tidal amplitude, wave height, cross- and along-shore wind magnitudes, and the vertical structure of the cross-shore flow was studied for each of these subsets. Despite different forcing conditions, the cross-shore velocity profiles usually show a vertical parabolic structure with maximum onshore flow at mid-depth, resembling the upwelling return flow for mid-shelf conditions, but atypical for the inner-shelf and in disagreement with other inner-shelf studies from other sites. We compare the observations with simplified 2D inner-shelf models and with results from other studies.

  18. Construction and modification of the autonomy of school mathematical knowledge in Portugal

    Directory of Open Access Journals (Sweden)

    José Manuel Matos

    2016-01-01

    Full Text Available During the second half of the nineteenth century and early twentieth century the discipline of secondary mathematics was gradually built in Portugal and certified teachers, textbooks, programs, special teaching techniques emerge. This consolidation process ends with the emergency of school subjects that develop some kind of autonomy as Chervel puts it. This article discusses how the school discipline of mathematics in secondary education in Portugal was set. This process is inseparable from teacher training and so we will observe professional legitimation processes paying special attention to ways in which autonomy has been building and modifying over time.

  19. Propolis volatiles characterisation from acaricide-treated and -untreated beehives maintained at Algarve (Portugal).

    Science.gov (United States)

    Miguel, Maria G; Nunes, Susana; Cruz, Cláudia; Duarte, João; Antunes, Maria D; Cavaco, Ana M; Mendes, Marta D; Lima, A Sofia; Pedro, Luis G; Barroso, José G; Figueiredo, A Cristina

    2013-04-01

    The variability of the volatile profile of 70 propolis samples from acaricide-treated and -untreated beehives maintained at Algarve (Portugal) was evaluated. Propolis samples were collected in three regions of Algarve at three different periods. Cluster analysis based on the propolis volatiles' chemical composition defined two main clusters, not related to the time of year, collection site, altitude, temperature or humidity ranges, and was based mainly on the relative amounts of viridiflorol, n-tricosane and n-nonadecane for cluster I. Cluster II was mainly characterised by the high thymol content, followed by viridiflorol, n-tricosane and n-nonadecane. The presence of higher thymol levels in propolis samples from cluster II may reflect the long use of an acaricide with thymol as main active ingredient. All samples showed an intense rock-rose aroma supported by the presence of characteristic Cistus and labdanum oil volatile components. Given the nowadays frequent propolis household use, volatiles thorough characterisation may assist in its quality assessment.

  20. Cancro do pulmão no norte de Portugal: um estudo de base hospitalar

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    V. Hespanhol

    2013-11-01

    Full Text Available Resumo: Introdução: O cancro do pulmão é o cancro que mais mortalidade determina em todo mundo. Em Portugal a doença mantém-se a principal causa de morte por cancro no sexo masculino. Objetivo: Neste estudo pretendeu-se avaliar as características demográficas e clínicas dos doentes com cancro do pulmão diagnosticados e tratados nos hospitais do norte de Portugal entre os anos 2000-2010. Doentes e métodos: Doze hospitais contribuíram para este estudo. Foram analisadas as características demográficas e clínicas dos doentes com cancro do pulmão registados em cada hospital, entre os anos 2000-2010, nos hospitais do norte de Portugal, bem como os padrões de ocorrência da doença. Resultados: Ao longo de um período de 11 anos (2000-2010, 9.767 doentes com cancro do pulmão foram registados nos hospitais participantes. Identificamos um importante aumento no número de doentes registados em relação aos registados em 2000. No sexo feminino observou-se uma elevação da ocorrência atingindo os 30%, o que é significativo, apesar do cancro do pulmão nas mulheres, em Portugal, ser muito menos frequente que nos homens e nesta série representar apenas 20% dos casos. Um número elevado de doentes, 3.117 (48,6%, tinha mau estado geral na altura que recorreram aos cuidados de saúde. O adenocarcinoma foi-se tornando a histologia mais preponderante ao longo do período de estudo. A maior parte dos doentes, 7.206 (77,8%, foi diagnosticada em estádios avançados (IIIB, IV da doença. A quimioterapia foi o tratamento escolhido para 3.529 (40,4% dos doentes, por outro lado, a cirurgia foi possível em 1.301 (14,9% dos casos. Conclusão: Um elevado número de doentes com cancro do pulmão é diagnosticado e tratado nos hospitais do norte de Portugal. A incidência no sexo feminino tem vindo a aumentar. A esmagadora maioria dos tumores foi diagnosticada em estádio avançado, tendo sido possível, apesar disso, tratar cirurgicamente 14,9% dos

  1. [Politicized sexualities: AIDS activism and sexual orientation in Portugal].

    Science.gov (United States)

    Santos, Ana Cristina

    2002-01-01

    This article analyzes how both the Portuguese state and civil society have addressed the AIDS issue, focusing on participation by the lesbian, gay, bisexual, and transsexual community (LGBT) in the struggle against AIDS. The article begins by describing the situation of LGBT individuals in Portugal during the 1990s, when the Portuguese LGBT movement emerged and grew, and then characterizes the evolution of HIV/AIDS in Portugal, analyzing the relationship between civil society and sexuality in general and the situation of the epidemic in the country in particular, considering key facts, nongovernmental organizations, and state initiatives. Special attention is given to the role played by LGBT organizations in the struggle against HIV. Finally, the article reflects on the future of the struggle against both AIDS and discrimination in the 21st century, considering recent events in the country and the guidelines recommended by international policies.

  2. Hydro-meteorological extreme events in the 18th century in Portugal

    Science.gov (United States)

    Fragoso, Marcelo; João Alcoforado, Maria; Taborda, João Paulo

    2013-04-01

    The present work is carried out in the frame of the KLIMHIST PROJECT ("Reconstruction and model simulations of past climate in Portugal using documentary and early instrumental sources, 17th-19th century)", and is devoted to the study of hydro-meteorological extreme events during the last 350 years, in order to understand how they have changed in time and compare them with current analogues. More specifically, the results selected to this presentation will focus on some hydro-meteorological extreme events of the 18th century, like severe droughts, heavy precipitation episodes and windstorms. One of the most noteworthy events was the winterstorm Bárbara (3rd to 6th December 1739), already studied in prior investigations (Taborda et al, 2004; Pfister et al, 2010), a devastating storm with strong impacts in Portugal caused by violent winds and heavy rainfall. Several other extreme events were detected by searching different documentary archives, including individual, administrative and ecclesiastic sources. Moreover, a more detailed insight to the 1783-1787 period will be made with regard the Lisbon region, taking into consideration the availability of information for daily meteorological observations as well as documentary evidences, like descriptions from Gazeta de Lisboa, the periodic with more continuous publication in the 18thcentury. Key-words: Instrumental data, Documentary data, Extreme events, Klimhist Project, Portugal References Pfister, C., Garnier, E., Alcoforado, M.J., Wheeler, D. Luterbacher, J. Nunes, M.F., Taborda, J.P. (2010) The meteorological framework and the cultural memory of three severe winter-storms in early eighteenth-century Europe, Climatic Change, 101, 1-2, 281-310 Taborda, JP; Alcoforado, MJ and Garcia, JC (2004) O Clima do Sul de Portugal no Séc.XVIII, Centro de Estudos Geográficos, Área de de Investigação de Geo-Ecologia, relatório no 2

  3. A hybrid PSO-ANFIS approach for short-term wind power prediction in Portugal

    International Nuclear Information System (INIS)

    Pousinho, H.M.I.; Mendes, V.M.F.; Catalao, J.P.S.

    2011-01-01

    The increased integration of wind power into the electric grid, as nowadays occurs in Portugal, poses new challenges due to its intermittency and volatility. Wind power prediction plays a key role in tackling these challenges. The contribution of this paper is to propose a new hybrid approach, combining particle swarm optimization and adaptive-network-based fuzzy inference system, for short-term wind power prediction in Portugal. Significant improvements regarding forecasting accuracy are attainable using the proposed approach, in comparison with the results obtained with five other approaches.

  4. Short-term wind power forecasting in Portugal by neural networks and wavelet transform

    Energy Technology Data Exchange (ETDEWEB)

    Catalao, J.P.S. [Department of Electromechanical Engineering, University of Beira Interior, R. Fonte do Lameiro, 6201-001 Covilha (Portugal); Center for Innovation in Electrical and Energy Engineering, Instituto Superior Tecnico, Technical University of Lisbon, Av. Rovisco Pais, 1049-001 Lisbon (Portugal); Pousinho, H.M.I. [Department of Electromechanical Engineering, University of Beira Interior, R. Fonte do Lameiro, 6201-001 Covilha (Portugal); Mendes, V.M.F. [Department of Electrical Engineering and Automation, Instituto Superior de Engenharia de Lisboa, R. Conselheiro Emidio Navarro, 1950-062 Lisbon (Portugal)

    2011-04-15

    This paper proposes artificial neural networks in combination with wavelet transform for short-term wind power forecasting in Portugal. The increased integration of wind power into the electric grid, as nowadays occurs in Portugal, poses new challenges due to its intermittency and volatility. Hence, good forecasting tools play a key role in tackling these challenges. Results from a real-world case study are presented. A comparison is carried out, taking into account the results obtained with other approaches. Finally, conclusions are duly drawn. (author)

  5. Origin and Population Dynamics of a Novel HIV-1 Subtype G Clade Circulating in Cape Verde and Portugal.

    Science.gov (United States)

    de Pina-Araujo, Isabel Inês M; Delatorre, Edson; Guimarães, Monick L; Morgado, Mariza G; Bello, Gonzalo

    2015-01-01

    The human immunodeficiency virus type 1 (HIV-1) subtype G is the most prevalent and second most prevalent HIV-1 clade in Cape Verde and Portugal, respectively; but there is no information about the origin and spatiotemporal dispersal pattern of this HIV-1 clade circulating in those countries. To this end, we used Maximum Likelihood and Bayesian coalescent-based methods to analyze a collection of 578 HIV-1 subtype G pol sequences sampled throughout Portugal, Cape Verde and 11 other countries from West and Central Africa over a period of 22 years (1992 to 2013). Our analyses indicate that most subtype G sequences from Cape Verde (80%) and Portugal (95%) branched together in a distinct monophyletic cluster (here called G(CV-PT)). The G(CV-PT) clade probably emerged after a single migration of the virus out of Central Africa into Cape Verde between the late 1970s and the middle 1980s, followed by a rapid dissemination to Portugal a couple of years later. Reconstruction of the demographic history of the G(CV-PT) clade circulating in Cape Verde and Portugal indicates that this viral clade displayed an initial phase of exponential growth during the 1980s and 1990s, followed by a decline in growth rate since the early 2000s. Our data also indicate that during the exponential growth phase the G(CV-PT) clade recombined with a preexisting subtype B viral strain circulating in Portugal, originating the CRF14_BG clade that was later disseminated to Spain and Cape Verde. Historical and recent human population movements between Angola, Cape Verde and Portugal probably played a key role in the origin and dispersal of the G(CV-PT )and CRF14_BG clades.

  6. Potential of Biomass for Energy. Market Survey Portugal

    International Nuclear Information System (INIS)

    2007-03-01

    The objective of this market survey is to provide information about the biomass sector in Portugal, relevant to mainly small and medium-sized enterprises (SME) in the Netherlands that are interested to strengthen their position in that sector. Much knowledge could be gathered from conversations with the partners of Sunergy, the company responsible for this survey. Sunergy is producing bio-diesel, and considering further investments in the solid biomass sector, and therefore well familiar with the developments. Other interviews were held with representatives of the Government (DGGE), association of forestry owners (AFLOPS), a biomass trading SME (Sobioen), the leading environmental NGO (Quercus), and an association representing the paper- and pulp industry (CELPA). Chapter 1 is a general introduction on biomass. Chapter 2 gives the background of the Portuguese energy sector and the relative importance of renewable and biomass energies within this market. Some prospects for future developments of the different renewable sources are given. Portugal's energy sector is dominated by a small number of players, which are introduced. Also the current policies and incentives (subsidies) are presented. In Chapter 3 the focus is on the Portuguese biomass sector, presenting the current use of biomass in each of the subsectors: transport, electricity and heat, and an overview of the policy framework specifically for biomass. Chapter 4 is a literature review of the market for existing and potential biomass resources, including demand, supply and other characteristics. Chapter 5 synthesizes the previous chapters. Also an overview of key drivers and key constraints for growth of this sector is given, leading to conclusions regarding the opportunities for Dutch companies. Finally, further information on how to proceed once the interest for Portugal's biomass sector is vested is listed at the end of Chapter 5

  7. Characterization of the medical department of pharmaceutical companies operating in Portugal

    Directory of Open Access Journals (Sweden)

    Acílio Gala

    2017-04-01

    Full Text Available In a context of strong regulatory demands and high economic pressures and constraints, medical departments within pharmaceutical companies, have demonstrated its strategic relevance even though the functions to embrace are not globally consensual. In this context, a study that intended to analyse the management of medical activities, in pharmaceutical companies operating in Portugal, including allocated human resources and investment trends, was implemented. Quantitative information was collected through an electronic survey, in pharmaceutical companies with activity in Portugal. The analysis of the results supported the conclusion that the majority of the companies are affiliates of international companies and that 79% of them have formalized medical departments. The human resources of the medical departments of the participant companies include several professional classes, with predominance of pharmacists. Globally, the number of employees of the medical area has registered a systematic growth in the last years. It was also possible to conclude that the majority of the companies are increasing the investment in medical affairs activities. This study enables the understanding of these activities in pharmaceutical companies operating in Portugal, within the international panorama of pharmaceutical industry. It contributes to improve the knowledge about the relevance of medical departments while enabling the definition of novel pathways to increase the competiveness and sustainability of the companies.

  8. First report of canine ocular thelaziosis by Thelazia callipaeda in Portugal

    Directory of Open Access Journals (Sweden)

    Vieira Lisete

    2012-06-01

    Full Text Available Background Thelazia callipaeda eyeworms are transmitted by the non-biting insect vector Phortica variegata in Europe and infest the conjunctiva(s of several mammalians, including dogs and humans. Infested hosts might remain asymptomatic or display clinical manifestations characterized by variable degrees of severity. Methods From July to November 2011, nine dogs were detected with eyeworms at two veterinary clinics in Chaves and Bragança (North of Portugal. Nematodes collected from dogs were morphologically and molecularly characterized at species level. Results Nematodes were identified as T. callipaeda. The number of worms collected from each dog ranged from three to 76 (average = 17.9 ± 26.8 and was not associated with the severity of clinical signs. Ocular discharge and conjunctivitis were observed in all dogs and ocular pruritus occurred in six of them. Polymerase chain reaction and sequencing of a portion of target cytochrome c oxidase subunit 1 gene further identified all nematodes as haplotype 1. Conclusions This is the first report of T. callipaeda and associated ocular disease in dogs from Portugal, suggesting that thelaziosis should be included in the differential diagnosis of canine ocular affections. The risk of the infestation spreading from Spain and France to Portugal, through domestic dogs or wild mammals, is realistic.

  9. The teaching about the care of the elderly in nursing training: the situation in Portugal

    Directory of Open Access Journals (Sweden)

    Silvana Sidney Costa Santos

    2013-09-01

    Full Text Available This paper aims to look at the teaching situation of the nursing undergraduate degree’s courses about eldercare in Portugal. A documentary research on the teaching programs in 39 nursing schools, 26 schools presented syllabus units related to the topic ‘eldercare’ and in eight of these schools the contents of the units were identified. Using textual analysis and from the categories we concluded that the teaching regarding eldercare for the nurse training in Portugal is focused on hospital care; it is directed to the adult/elderly/family; it explores the definitions related to the aging process; it explores community issues, legislation and research. People responsible for the design/monitoring of teaching programs should include teaching regarding eldercare in the nurse training, considering that the elder population is increasing in Portugal.

  10. Optical conductivity of Ni1 − xPtx alloys (0

    Directory of Open Access Journals (Sweden)

    Lina S. Abdallah

    2014-01-01

    Full Text Available Using spectroscopic ellipsometry and Drude-Lorentz oscillator fitting, we determined the dielectric function and optical conductivity versus photon energy from 0.76 to 6.6 eV of 10 nm thick Ni1 − xPtx alloy (0

  11. Diferenças entre marcas nos serviços multiple-play em Portugal

    OpenAIRE

    Silva, Pedro; Moreira, António; Moutinho, Victor

    2014-01-01

    A concorrência entre operadores do mercado das telecomunicações em Portugal tem sido intensa.Os serviços multiple-play têm vindo a conquistar a preferência dos portugueses e a oferta tem vindo a aumentar ao longo dos anos. Face ao aumento da competitividade dos principais concorrentes, seria de esperar que os desempenhos das suas marcas fossem muito equilibrados. O objetivo deste artigo é o de analisar as diferenças entre as três principais marcas multiple-play em Portugal. Para tal, foi efet...

  12. A hybrid PSO-ANFIS approach for short-term wind power prediction in Portugal

    Energy Technology Data Exchange (ETDEWEB)

    Pousinho, H.M.I. [Department of Electromechanical Engineering, University of Beira Interior, R. Fonte do Lameiro, 6201-001 Covilha (Portugal); Mendes, V.M.F. [Department of Electrical Engineering and Automation, Instituto Superior de Engenharia de Lisboa, R. Conselheiro Emidio Navarro, 1950-062 Lisbon (Portugal); Catalao, J.P.S. [Department of Electromechanical Engineering, University of Beira Interior, R. Fonte do Lameiro, 6201-001 Covilha (Portugal); Center for Innovation in Electrical and Energy Engineering, Instituto Superior Tecnico, Technical University of Lisbon, Av. Rovisco Pais, 1049-001 Lisbon (Portugal)

    2011-01-15

    The increased integration of wind power into the electric grid, as nowadays occurs in Portugal, poses new challenges due to its intermittency and volatility. Wind power prediction plays a key role in tackling these challenges. The contribution of this paper is to propose a new hybrid approach, combining particle swarm optimization and adaptive-network-based fuzzy inference system, for short-term wind power prediction in Portugal. Significant improvements regarding forecasting accuracy are attainable using the proposed approach, in comparison with the results obtained with five other approaches. (author)

  13. LIS Education in Portugal between Academia and Practice

    Science.gov (United States)

    Ribeiro, Fernanda

    2008-01-01

    There is a brief exposition, in a historical perspective, about the evolution of the professional education in Portugal, in the area of Library and Information Science, since the creation of the Curso de Bibliotecario-Arquivista, in 1887, until its closure in 1982, when it was replaced by the Curso de Especializacao em Ciencias Documentais (CECD).…

  14. Imipenem Resistance in Clostridium difficile Ribotype 017, Portugal

    Science.gov (United States)

    Isidro, Joana; Santos, Andrea; Nunes, Alexandra; Borges, Vítor; Silva, Catarina; Vieira, Luís; Mendes, Aristides L.; Serrano, Mónica; Henriques, Adriano O.; Gomes, João Paulo

    2018-01-01

    We describe imipenem-resistant and imipenem-susceptible clinical isolates of Clostridium difficile ribotype 017 in Portugal. All ribotype 017 isolates carried an extra penicillin-binding protein gene, pbp5, and the imipenem-resistant isolates had additional substitutions near the transpeptidase active sites of pbp1 and pbp3. These clones could disseminate and contribute to imipenem resistance. PMID:29553322

  15. Contractual medical liability in Portugal and Macao

    Directory of Open Access Journals (Sweden)

    Rui Miguel Prista Patrício Cascão

    2016-09-01

    Full Text Available Liability of healthcare providers can be framed under the theory of contract in the law of Portugal and Macao, to obtain compensation for injury suffered by aggrieved patients, as a result of medical adverse events. However, shortcomings in the law, court practice and literature lead to some uncertainty in adjudication. This article aims at reducing said uncertainty, setting forward a clear-cut adjudication paradigm, while recommending legal reform.

  16. Le crayon bleu de la censure : oeuvres d’auteurs français interdites au Portugal entre 1933 et 1974

    OpenAIRE

    Gonçalves, Luís Carlos Pimenta

    2017-01-01

    The Censor’s Blue Pen: Works by French Authors Banned in Portugal between 1933 and 1974. The dictatorial regime imposed by the Estado Novo regime in force in Portugal between 1933 and 1974 imposed a severe censorship of publications in general and more specifically to books published in Portugal and abroad. Because of the influence that French culture had, many authors, ancient and contemporary, from Flaubert to Sartre going through Sagan, had their works banned. The reasons for the ban were ...

  17. Järgmine Iirimaa on Portugal / Soe-Surén, Katri

    Index Scriptorium Estoniae

    Soe-Surén, Katri

    2010-01-01

    Ekspertide hinnangul on Portugal järgmine riik, mis vajab finantsabi. Portugali jooksevkonto defitsiit on sel aastal üle 10% SKT-st, Iirimaal 0,3%. Portugali majandustoodang langeb 2011. a., Iirimaal aga peaks majandus kasvama 1,5%

  18. Determinant Factors of the Implementation of the Balanced Scorecard in Portugal: empirical evidence in public and private organizations

    Directory of Open Access Journals (Sweden)

    Patricia Rodrigues Quesado

    2014-09-01

    Full Text Available In this article we aim to identify and analyze a set of variables that can potentially influence the adoption of the Balanced Scorecard (BSC in Portugal. Hypotheses were tested using data obtained from a questionnaire sent to 591 publicly-owned organizations (local governments, municipal corporations and hospitals and 549 privately-owned organizations (large companies and small and medium enterprises in Portugal, with an overall response rate of 31.3%. The results allow us to conclude that although the majority of respondents claimed to know the BSC, its use in Portugal is still limited and very recent, particularly in the public sector organizations. However, it should be noted that its use has increased in Portugal in recent years. Using as theoretical framework the contingency and institutional theories, we found that decentralization, vertical differentiation and the degree of higher education are associated with the implementation of the BSC.

  19. Eimeria infections in goats in Southern Portugal

    Directory of Open Access Journals (Sweden)

    Liliana Machado Ribeiro da Silva

    Full Text Available Coccidiosis caused by Eimeria species is a major form of intestinal infection affecting intensively and semi-intensively reared goats. The province of Alentejo is the main goat-producing area in Portugal. Therefore, all 15 Serpentina goat farms in Alentejo were analyzed regarding the occurrence and diversity of Eimeria species. Fecal samples obtained from 144 animals (52.1% dairy goats, 47.9% pre-pubertal goats were examined using the modified McMaster technique to determine the number of oocysts per gram of feces. Eimeria spp. oocysts were present in 98.61% of the fecal samples and, overall, nine different Eimeria species were identified. The most prevalent species were E. ninakohlyakimovae (88% and E. arloingi (85%, followed by E. alijevi (63% and E. caprovina(63%. The average number of oocysts shed was significantly lower in dairy goats than in pre-adult animals. Astonishingly, no clinical signs of coccidiosis were observed in any of the animals examined, even though they were shedding high numbers of oocysts and were infected with highly pathogenic species. Thus, implementation of routine diagnostic investigation of the occurrence and diversity of caprine Eimeria species may be a useful tool for determination and better understanding of their potential economic impact on goat herds in southern Portugal.

  20. Portugal y su imperio frente a la descolonización 1945-62

    Directory of Open Access Journals (Sweden)

    Adolfo Cueto

    2011-01-01

    Full Text Available Portugal logró construir un imperio colonial en África tan notable como desajustado a las aparentes capacidades del país, y eso fue gracias a una difícil combinación de factores endógenos y exógenos, un éxito que llevó a que los dirigentes lusos confiriesen al Ultramar un papel ideológico capital. Sin embargo, tras la Segunda Guerra Mundial los factores externos que habían favorecido la materialización del Imperio desaparecen, y en este nuevo contexto marcado por la Guerra Fría y la ola descolonizadora, Portugal es incapaz de contemporizar sus relaciones con las colonias. El temor a que la pérdida de los territorios extraeuropeos acabase también con el Régimen, además de otros factores, determinó la imposibilidad de que el Gobierno aceptase revisar sustancialmente su política inmovilista, obligándose a sostenerla en circunstancias internacionales y nacionales extremadamente difíciles, especialmente a partir de 1961. A pesar de la evidente imposibilidad de mantener la soberanía en Ultramar por la fuerza en ese contexto, para buena parte de la cúpula del Estado Novo cualquier alternativa que pusiese en cuestión la «unidad pluricontinental de Portugal y sus provincias ultramarinas» era inaceptable, al ser la piedra angular que sostenía el mito del «caso único» del colonialismo portugués y por consiguiente la justificación de su continuidad, siendo además el dogma que impedía una discusión interior abierta y perniciosa sobre el futuro de las colonias — obviamente junto a la propia naturaleza antidemocrática del Régimen. Por esa razón, el único camino posible era el de la guerra, complementada con algunas reformas administrativas, económicas y sociales que ejecutaría Adriano Moreira, y que no pudieron ser otra cosa que una certificación de los estrechos límites en los que el Portugal de Salazar podía moverse.Portugal managed to build a colonial empire in Africa which was as remarkable as out of proportion

  1. Patterns of glucose lowering drugs utilization in Portugal and in the Netherlands. Trends over time.

    Science.gov (United States)

    Torre, Carla; Guerreiro, José; de Oliveira Martins, Sofia; Raposo, João Filipe; Martins, Ana Paula; Leufkens, Hubert

    2015-12-01

    To compare the temporal trends in the consumption patterns of glucose lowering drugs (GLD) between Portugal and the Netherlands from 2004 to 2013 and to examine possible reasons behind the cross-national variation found. All GLD (ATC pharmacological subgroup A10B) were selected for analysis. Consumption data were obtained for the 10-year period. Portuguese and Dutch drug estimates were obtained from nationwide databases. The consumption of GLD increased in Portugal from 52.9 defined daily dose per 1000 inhabitants per day (DHD) in 2004 to 70.0 DHD in 2013 and in the Netherlands from 44.9 DHD in 2004 to 50.7 DHD in 2013. In Portugal, the use of fixed-dose combinations, especially with dipeptidyl peptidase-4 inhibitors (DPP-4) increased remarkably and in 2013 represented almost a quarter of total GLD consumption. In the Netherlands, the use of combinations was residual. The consumption of GLD rose over the 10-year period in both countries. However, Portuguese overall consumption and costs of GLD were higher. The differentially rapid uptake of DPP-4 inhibitors in Portugal was the main driver of the cost difference. Copyright © 2015 Primary Care Diabetes Europe. Published by Elsevier Ltd. All rights reserved.

  2. School-Based Sexuality Education in Portugal: Strengths and Weaknesses

    Science.gov (United States)

    Rocha, Ana Cristina; Leal, Cláudia; Duarte, Cidália

    2016-01-01

    Portugal, like many other countries, faces obstacles regarding school-based sexuality education. This paper explores Portuguese schools' approaches to implementing sexuality education at a local level, and provides a critical analysis of potential strengths and weaknesses. Documents related to sexuality education in a convenience sample of 89…

  3. Med H.C. Andersen i Portugal år 1866

    DEFF Research Database (Denmark)

    Skousbøll, Karin

    2004-01-01

    ankomst med diligence fra Spanien ind over fastlandet til Lissabon, men også rundt i byen, i omegnen og til havnebyen Setubal. Det indsamlede billedstof som underbygger teksten er dels historisk stof indhentet fra Det kg. Bibliotek o.a. kilder og dels fremskaffet fra Portugals arkiver og de respektive...

  4. La promoción y gestión de los polígonos industriales en la Eurorregión Galicia-Norte de Portugal Promotion and management in industrial states of the Euroregion Galicia-North of Portugal

    Directory of Open Access Journals (Sweden)

    Jesús García-Arca

    2011-09-01

    Full Text Available En un entorno global, para reforzar la competitividad de las empresas es necesario adoptar políticas de desarrollo de infraestructuras logísticas y de polígonos industriales. Sin embargo, a pesar del impacto económico y social que generan estos polígonos industriales, su adecuada promoción y gestión no se ha destacado, especialmente en España. En este contexto, este artículo profundiza en las causas que conducen a una deficiente promoción y gestión de los polígonos industriales, proponiendo líneas de actuación su mejora. Para ilustrar esta problemática general, se analiza la promoción y gestión de los polígonos industriales en la Eurorregión Galicia-Norte de Portugal (provincia de Pontevedra en España y la zona de Minho-Lima en el distrito portugués de Viana do Castelo. Si bien el estudio de campo se centra en el ámbito fronterizo de la Eurorregión Galicia-Norte de Portugal, las conclusiones y recomendaciones del estudio son perfectamente extrapolables al resto de España y Portugal.This paper not only makes a deep analysis of the main causes that imply problems in promotion and management in industrial estates, but also proposes an action plan to improve the current situation. In order to illustrate these problems, the situation of industrial estates in the Euroregion Galicia-North of Portugal (Pontevedra area in Spain and Minho-Lima area in Viana do Castelo, Portugal was presented. Although the study focused only on these geographical areas (55 companies, the conclusions and recommendations could be easily extrapolated to the rest of Spain and Portugal. Among these conclusions, the need for a better strategy to locate new industrial estates, for a higher development of services and infrastructures, and for the adoption of suitable organizational schemes to the maintenance of industrial estates, could be outlined.

  5. Research Management in Portugal: A Quest for Professional Identity

    Science.gov (United States)

    Trindade, Margarida; Agostinho, Marta

    2014-01-01

    Research managers at science-intensive institutions appear as a continuously evolving group of professionals whose identity is somewhat fragmented, even to themselves. In Portugal, specialized research manager roles have rapidly emerged over the last years alongside the development of a small but consolidated scientific system. In order to get an…

  6. Education and Equality in Portugal: The Role of Priority Education Policies

    Directory of Open Access Journals (Sweden)

    Maria Dias

    2013-03-01

    Full Text Available This article addresses priority education policies developed in Portugal and focuses on the latest intervention trends in this regard. Firstly, the contexts in which these policies emerged are described with respect to the country’s specificity concerning the universalization of basic education and compulsory schooling, as well as social and educational equity. Secondly, the main current governmental initiative in the field, Priority Intervention Education Territories (TEIP2, is analyzed. It aims to reduce school failure and school dropout in deprived areas and attempts to fulfill the goals set for Europe in terms of education and training. We analyze TEIP2 program’s impact on students’ school achievement, dropout and on the possibilities of innovating pedagogical practices. We argue that significant changes have occurred in the conceptions and goals of priority education in Portugal, especially in what concerns the need for schools to acknowledge the sociological and cultural diversity of their students and families. However, it cannot be neglected that current policies show an important vulnerability in what concerns their ambitious goals, as they simultaneously try to achieve system modernization, social cohesion and reduction of social inequalities. In our opinion, the question of knowing if these principles and logics of action are compatible or can coexist is remaining, especially in the context of a deep economic and financial crisis that is nowadays prevailing in Portugal.

  7. Chemoresistance in prostate cancer cells is regulated by miRNAs and Hedgehog pathway.

    Directory of Open Access Journals (Sweden)

    Saurabh Singh

    Full Text Available Many prostate cancers relapse due to the generation of chemoresistance rendering first-line treatment drugs like paclitaxel (PTX ineffective. The present study aims to determine the role of miRNAs and Hedgehog (Hh pathway in chemoresistant prostate cancer and to evaluate the combination therapy using Hh inhibitor cyclopamine (CYA. Studies were conducted on PTX resistant DU145-TXR and PC3-TXR cell lines and clinical prostate tissues. Drug sensitivity and apoptosis assays showed significantly improved cytotoxicity with combination of PTX and CYA. To distinguish the presence of cancer stem cell like side populations (SP, Hoechst 33342 flow cytometry method was used. PTX resistant DU145 and PC3 cells, as well as human prostate cancer tissue possess a distinct SP fraction. Nearly 75% of the SP cells are in the G0/G1 phase compared to 62% for non-SP cells and have higher expression of stem cell markers as well. SP cell fraction was increased following PTX monotherapy and treatment with CYA or CYA plus PTX effectively reduced their numbers suggesting the effectiveness of combination therapy. SP fraction cells were allowed to differentiate and reanalyzed by Hoechst staining and gene expression analysis. Post differentiation, SP cells constitute 15.8% of total viable cells which decreases to 0.6% on treatment with CYA. The expression levels of P-gp efflux protein were also significantly decreased on treatment with PTX and CYA combination. MicroRNA profiling of DU145-TXR and PC3-TXR cells and prostate cancer tissue from the patients showed decreased expression of tumor suppressor miRNAs such as miR34a and miR200c. Treatment with PTX and CYA combination restored the expression of miR200c and 34a, confirming their role in modulating chemoresistance. We have shown that supplementing mitotic stabilizer drugs such as PTX with Hh-inhibitor CYA can reverse PTX chemoresistance and eliminate SP fraction in androgen independent, metastatic prostate cancer cell

  8. Co-delivery of cisplatin and paclitaxel by folic acid conjugated amphiphilic PEG-PLGA copolymer nanoparticles for the treatment of non-small lung cancer.

    Science.gov (United States)

    He, Zelai; Huang, Jingwen; Xu, Yuanyuan; Zhang, Xiangyu; Teng, Yanwei; Huang, Can; Wu, Yufeng; Zhang, Xi; Zhang, Huijun; Sun, Wenjie

    2015-12-08

    An amphiphilic copolymer, folic acid (FA) modified poly(ethylene glycol)-poly(lactic-co-glycolic acid) (FA-PEG-PLGA) was prepared and explored as a nanometer carrier for the co-delivery of cisplatin (cis-diaminodichloroplatinum, CDDP) and paclitaxel (PTX). CDDP and PTX were encapsulated inside the hydrophobic inner core and chelated to the middle shell, respectively. PEG provided the outer corona for prolonged circulation. An in vitro release profile of the CDDP + PTX-encapsulated nanoparticles revealed that the PTX chelation cross-link prevented an initial burst release of CDDP. After an incubation period of 24 hours, the CDDP+PTX-encapsulated nanoparticles exhibited a highly synergistic effect for the inhibition of A549 (FA receptor negative) and M109 (FA receptor positive) lung cancer cell line proliferation. Pharmacokinetic experiment and distribution research shows that nanoparticles have longer circulation time in the blood and can prolong the treatment times of chemotherapeutic drugs. For the in vivo treatment of A549 cells xeno-graft lung tumor, the CDDP+PTX-encapsulated nanoparticles displayed an obvious tumor inhibiting effect with an 89.96% tumor suppression rate (TSR). This TSR was significantly higher than that of free chemotherapy drug combination or nanoparticles with a single drug. For M109 cells xeno-graft tumor, the TSR was 95.03%. In vitro and in vivo experiments have all shown that the CDDP+PTX-encapsulated nanoparticles have better targeting and antitumor effects in M109 cells than CDDP+PTX-loaded PEG-PLGA nanoparticles (p nanoparticles came with reduced side-effects. No obvious body weight loss or functional changes occurred within blood components, liver, or kidneys during the treatment of A549 and M109 tumor-bearing mice with the CDDP+PTX-encapsulated nanoparticles. Thus, the FA modified amphiphilic copolymer-based combination of CDDP and PTX may provide useful guidance for effective and safe cancer chemotherapy, especially in tumors with

  9. Transnational citizenship : Latin Americans in Portugal

    OpenAIRE

    Padilla, Beatriz; Scaglione, Alejandra Ortiz

    2014-01-01

    Este artículo reflexiona sobre el ejercicio de la ciudadanía como consecuencia de la migración internacional, aplicado al caso de los latinoamericanos residentes en Portugal. Para ello adoptamos el concepto de ciudadanía transnacional por su maleabilidad, ya que permite considerar la perspectiva conjunta de los países de origen y de destino, así como también la influencia de las relaciones binacionales e internacionales. Nos preguntamos cómo se ejerce la ciudadanía transnacional en los espaci...

  10. Establishment of heart teams in Portugal.

    Science.gov (United States)

    Sousa Uva, M; Leite Moreira, A; Gavina, C; Pereira, H; Lopes, M G

    2014-01-01

    Whenever several therapeutic options exist, multidisciplinary decision-making is beneficial for the patient and for society at large. The main obstacles to the establishment of heart teams in Portugal are organizational and logistical. Implementing a heart team approach entails definition of the situations requiring multidisciplinary discussion, creation of clear lines of communication, written protocols and obtaining patient informed consent. The European Society of Cardiology guidelines define the clinical scenarios where intervention of the heart team is recommended. Copyright © 2013 Sociedade Portuguesa de Cardiologia. Published by Elsevier España. All rights reserved.

  11. Extracellular acidification synergizes with PDGF to stimulate migration of mouse embryo fibroblasts through activation of p38MAPK with a PTX-sensitive manner

    International Nuclear Information System (INIS)

    An, Caiyan; Sato, Koichi; Wu, Taoya; Bao, Muqiri; Bao, Liang; Tobo, Masayuki; Damirin, Alatangaole

    2015-01-01

    The elucidation of the functional mechanisms of extracellular acidification stimulating intracellular signaling pathway is of great importance for developing new targets of treatment for solid tumors, and inflammatory disorders characterized by extracellular acidification. In the present study, we focus on the regulation of extracellular acidification on intracellular signaling pathways in mouse embryo fibroblasts (MEFs). We found extracellular acidification was at least partly involved in stimulating p38MAPK pathway through PTX-sensitive behavior to enhance cell migration in the presence or absence of platelet-derived growth factor (PDGF). Statistical analysis showed that the actions of extracellular acidic pH and PDGF on inducing enhancement of cell migration were not an additive effect. However, we also found extracellular acidic pH did inhibit the viability and proliferation of MEFs, suggesting that extracellular acidification stimulates cell migration probably through proton-sensing mechanisms within MEFs. Using OGR1-, GPR4-, and TDAG8-gene knock out technology, and real-time qPCR, we found known proton-sensing G protein-coupled receptors (GPCRs), transient receptor potential vanilloid subtype 1 (TRPV1), and acid-sensing ion channels (ASICs) were unlikely to be involved in the regulation of acidification on cell migration. In conclusion, our present study validates that extracellular acidification stimulates chemotactic migration of MEFs through activation of p38MAPK with a PTX-sensitive mechanism either by itself, or synergistically with PDGF, which was not regulated by the known proton-sensing GPCRs, TRPV1, or ASICs. Our results suggested that others proton-sensing GPCRs or ion channels might exist in MEFs, which mediates cell migration induced by extracellular acidification in the presence or absence of PDGF. - Highlights: • Acidic pH and PDGF synergize to stimulate MEFs migration via Gi/p38MAPK pathway. • Extracellular acidification inhibits the

  12. Extracellular acidification synergizes with PDGF to stimulate migration of mouse embryo fibroblasts through activation of p38MAPK with a PTX-sensitive manner

    Energy Technology Data Exchange (ETDEWEB)

    An, Caiyan [Department of Biochemistry and Molecular Biology, College of Life Sciences, Inner Mongolia University, Hohhot, Inner Mongolia (China); Laboratory of Signal Transduction, Institute for Molecular and Cellular Regulation, Gunma University, Maebashi (Japan); Clinical Medicine Research Center of the Affiliated Hospital, Inner Mongolia Medical University, Hohhot, Inner Mongolia (China); Sato, Koichi [Laboratory of Signal Transduction, Institute for Molecular and Cellular Regulation, Gunma University, Maebashi (Japan); Wu, Taoya; Bao, Muqiri; Bao, Liang [Department of Biochemistry and Molecular Biology, College of Life Sciences, Inner Mongolia University, Hohhot, Inner Mongolia (China); Tobo, Masayuki [Laboratory of Signal Transduction, Institute for Molecular and Cellular Regulation, Gunma University, Maebashi (Japan); Damirin, Alatangaole, E-mail: bigaole@imu.edu.cn [Department of Biochemistry and Molecular Biology, College of Life Sciences, Inner Mongolia University, Hohhot, Inner Mongolia (China)

    2015-05-01

    The elucidation of the functional mechanisms of extracellular acidification stimulating intracellular signaling pathway is of great importance for developing new targets of treatment for solid tumors, and inflammatory disorders characterized by extracellular acidification. In the present study, we focus on the regulation of extracellular acidification on intracellular signaling pathways in mouse embryo fibroblasts (MEFs). We found extracellular acidification was at least partly involved in stimulating p38MAPK pathway through PTX-sensitive behavior to enhance cell migration in the presence or absence of platelet-derived growth factor (PDGF). Statistical analysis showed that the actions of extracellular acidic pH and PDGF on inducing enhancement of cell migration were not an additive effect. However, we also found extracellular acidic pH did inhibit the viability and proliferation of MEFs, suggesting that extracellular acidification stimulates cell migration probably through proton-sensing mechanisms within MEFs. Using OGR1-, GPR4-, and TDAG8-gene knock out technology, and real-time qPCR, we found known proton-sensing G protein-coupled receptors (GPCRs), transient receptor potential vanilloid subtype 1 (TRPV1), and acid-sensing ion channels (ASICs) were unlikely to be involved in the regulation of acidification on cell migration. In conclusion, our present study validates that extracellular acidification stimulates chemotactic migration of MEFs through activation of p38MAPK with a PTX-sensitive mechanism either by itself, or synergistically with PDGF, which was not regulated by the known proton-sensing GPCRs, TRPV1, or ASICs. Our results suggested that others proton-sensing GPCRs or ion channels might exist in MEFs, which mediates cell migration induced by extracellular acidification in the presence or absence of PDGF. - Highlights: • Acidic pH and PDGF synergize to stimulate MEFs migration via Gi/p38MAPK pathway. • Extracellular acidification inhibits the

  13. Sensory profile of portuguese white wines using long-term memory: a novel nationwide approach

    OpenAIRE

    Coutinho, A. J.; Ávila, P.; Silva, J. M.

    2015-01-01

    WOS:000362820600004 (Nº de Acesso Web of Science) White wine sensory profiling of all 12 Protected Geographical Indications (PGIs) of mainland Portugal was achieved through completion of extended sensory questionnaires by 20 professional wine experts. No samples were assessed; the experiment was based on memory alone. Three macro-zonings were found and typicality differences were statistically validated and sensory described. PGI MINHO was found the most typical of all PGIs, with several e...

  14. The Bologna Process in Portugal and Poland: A comparative study

    Directory of Open Access Journals (Sweden)

    Eduardo Tomé

    2016-04-01

    Full Text Available We analyze the consequences of the introduction of the EU directed Bologna Process in Portuguese and Polish Universities. Specifically, we study how the Bologna Process has impacted in the employment situations of graduates in Portugal and Poland. Concerning methodology, we use available official data on the implementation of the Bologna Process in Poland and Portugal. We have found that the investment in Higher Education (HE stalled in both countries in the years since the implementation of the Bologna Process due to massive budgetary restrictions. Nevertheless, the stock of HE graduates increased massively, seemingly because the authorities thought that the free market should lead the HE market in the two countries. Employment prospects, unemployment prospects and wages of graduates continued to be much higher than those of non-graduates. But an unexpected divide appeared between graduates and Masters/PhDs, with important social consequences. While the first “saved” themselves and prospered going into high skilled jobs, the later had to endure minimum wage and underskilled occupations. The low payment for these youngsters was also justified because the supply of HE with Bologna increased but the demand by companies did not match. In fact, both Portugal and Poland have stronger needs in the demand side of the market than in the supply side. Finally, both markets continue to be essentially public and the experiences of privatization did not succeed to much. In terms of social implications, the Bologna Process faces in both countries the massive and decisive challenge of eliminating youth unemployment and emigration but this can only be done with the cooperation of companies that should create high paid and high skilled jobs. Only when this occurs the Bologna Process will achieve its ultimate goal of transforming Portugal and Poland in high skilled equibriuns. Let us hope it happens, for the good of the two countries and particularly for the

  15. Testing continuous earthquake detection and location in Alentejo (South Portugal) by waveform coherency analysis

    Science.gov (United States)

    Matos, Catarina; Grigoli, Francesco; Cesca, Simone; Custódio, Susana

    2015-04-01

    In the last decade a permanent seismic network of 30 broadband stations, complemented by dense temporary deployments, covered Portugal. This extraordinary network coverage enables now the computation of a high-resolution image of the seismicity of Portugal, which in turn will shed light on the seismotectonics of Portugal. The large data volumes available cannot be analyzed by traditional time-consuming manual location procedures. In this presentation we show first results on the automatic detection and location of earthquakes occurred in a selected region in the south of Portugal Our main goal is to implement an automatic earthquake detection and location routine in order to have a tool to quickly process large data sets, while at the same time detecting low magnitude earthquakes (i.e., lowering the detection threshold). We present a modified version of the automatic seismic event location by waveform coherency analysis developed by Grigoli et al. (2013, 2014), designed to perform earthquake detections and locations in continuous data. The event detection is performed by continuously computing the short-term-average/long-term-average of two different characteristic functions (CFs). For the P phases we used a CF based on the vertical energy trace, while for S phases we used a CF based on the maximum eigenvalue of the instantaneous covariance matrix (Vidale 1991). Seismic event detection and location is obtained by performing waveform coherence analysis scanning different hypocentral coordinates. We apply this technique to earthquakes in the Alentejo region (South Portugal), taking advantage from a small aperture seismic network installed in the south of Portugal for two years (2010 - 2011) during the DOCTAR experiment. In addition to the good network coverage, the Alentejo region was chosen for its simple tectonic setting and also because the relationship between seismicity, tectonics and local lithospheric structure is intriguing and still poorly understood. Inside

  16. Deforestation in Portugal

    Directory of Open Access Journals (Sweden)

    João Branco

    2014-01-01

    Full Text Available Deforestation is not a new problem although world-wide population awareness is increasing. This issue has terrible environmental, social and economic consequences due to the over-exploitation of the natural resources and to alternative land uses which are more profitable in the short term. The combat and mitigation of deforestation is one of the biggest challenges for the 21st Century in order to achieve the Millennium Goals and a global sustainable development at all levels of human activities. Therefore, this paper will address this concerns focusing on the causes and consequences of deforestation as well as on the actions carried out by the decision makers in order to provide solutions for this increasingly and alarming problem. This paper will also approach the concepts of sustainability as well as the economy and management of the natural resources aiming an insight of the past deforestation in Portugal, the present situation and a sustainable perspective regarding the future.

  17. Novel thermo-sensitive core-shell nanoparticles for targeted paclitaxel delivery

    International Nuclear Information System (INIS)

    Li Yuanpei; Pan Shirong; Zhang Wei; Du Zhuo

    2009-01-01

    Novel thermo-sensitive nanoparticles self-assembled from poly(N,N-diethylacrylamide- co-acrylamide)-block-poly(γ-benzyl L-glutamate) were designed for targeted drug delivery in localized hyperthermia. The lower critical solution temperature (LCST) of nanoparticles was adjusted to a level between physiological body temperature (37 deg. C) and that used in local hyperthermia (about 43 deg. C). The temperature-dependent performances of the core-shell nanoparticles were systemically studied by nuclear magnetic resonance (NMR), circular dichroism (CD), fluorescence spectroscopy, dynamic light scattering (DLS), and atom force microscopy (AFM). The mean diameter of the nanoparticles increased slightly from 110 to 129 nm when paclitaxel (PTX), a poorly water-soluble anti-tumor drug, was encapsulated. A stability study in bovine serum albumin (BSA) solution indicated that the PTX loaded nanoparticles may have a long circulation time under physiological environments as the LCST was above physiological body temperature and the shell remained hydrophilic at 37 deg.C. The PTX release profiles showed thermo-sensitive controlled behavior. The proliferation inhibiting activity of PTX loaded nanoparticles was evaluated against Hela cells in vitro, compared with Taxol (a formulation of paclitaxel dissolved in Cremophor EL and ethanol). The cytotoxicity of PTX loaded nanoparticles increased obviously when hyperthermia was performed. The nanoparticles synthesized here could be an ideal candidate for thermal triggered anti-tumor PTX delivery system.

  18. Impact of Chronic Renal Failure on Safety and Effectiveness of Paclitaxel-Eluting Stents for Femoropopliteal Artery Disease: Subgroup Analysis from Zilver PTX Post-Market Surveillance Study in Japan.

    Science.gov (United States)

    Ogawa, Yukihisa; Yokoi, Hiroyoshi; Ohki, Takao; Kichikawa, Kimihiko; Nakamura, Masato; Komori, Kimihiro; Nanto, Shinsuke; O'Leary, Erin E; Lottes, Aaron E; Saunders, Alan T; Dake, Michael D

    2017-11-01

    Favorable long-term outcomes of the Zilver PTX drug-eluting stent (DES) in femoropopliteal lesions have been demonstrated. Chronic renal failure (CRF) has been shown to be a risk factor for restenosis and decreased limb salvage. The results of the DES in patients with CRF have not previously been reported. This study compares the results with the DES in patients with CRF and those without CRF. This retrospective analysis from the Zilver PTX Japan Post-Market Surveillance Study included 321 patients with CRF and 584 patients without CRF. Outcomes included freedom from target lesion revascularization (TLR) and patency. Of the patients included in this subgroup analysis, 2-year data were available for 209 patients in the CRF group and 453 patients in the non-CRF group. The two groups were similar in terms of lesion length and the frequency of in-stent restenosis. Critical limb ischemia, severe calcification, and diabetes were more common in patients with CRF, whereas total occlusion was more common in patients without CRF. Freedom from TLR rates were 81.4 versus 84.9% (p = 0.24), and patency rates were 70.7 versus 70.3% (p = 0.95) in patients with and without CRF at 2 years, respectively. This is the first comparative study of the DES in femoropopliteal artery lesions in patients with and without CRF. These results indicate that the DES placed in femoropopliteal artery lesions of CRF patients is safe and effective with similar patency and TLR rates to patients without CRF. Level 3, Post-Market Surveillance Study.

  19. Molecular epidemiology of Bordetella pertussis in Cambodia determined by direct genotyping of clinical specimens.

    Science.gov (United States)

    Moriuchi, Takumi; Vichit, Ork; Vutthikol, Yong; Hossain, Md Shafiqul; Samnang, Chham; Toda, Kohei; Grabovac, Varja; Hiramatsu, Yukihiro; Otsuka, Nao; Shibayama, Keigo; Kamachi, Kazunari

    2017-09-01

    This study sought to determine the genotypes of circulating Bordetella pertussis, the causative agent of pertussis, in Cambodia by direct molecular typing of clinical specimens. DNA extracts from nasopharyngeal swabs obtained from 82 pertussis patients in 2008-2016 were analyzed by multilocus variable-number tandem repeat analysis (MLVA). B. pertussis virulence-associated allelic genes (ptxA, prn, and fim3) and the pertussis toxin promoter ptxP were also investigated by DNA sequence-based typing. Forty-four DNA extracts (54%) yielded a complete MLVA profile, and these were sorted into 8 MLVA types (MT18, MT26, MT27, MT29, MT43, MT72, MT95, and MT200). MT27 and MT29, which are common in developed countries, were the predominant strain types (total 73%). The predominant profile of virulence-associated allelic genes was the combination of ptxP3/ptxA1/prn2/fim3A (48%). MT27 strains were detected during the entire study period, whereas MT29 strains were only found in 2014-2016. The B. pertussis population in Cambodia, where a whole-cell pertussis vaccine (WCV) has been continuously used, resembled those observed previously in developed countries where acellular pertussis vaccines are used. Circulating B. pertussis strains in Cambodia were distinct from those in other countries using WCVs. Copyright © 2017 The Author(s). Published by Elsevier Ltd.. All rights reserved.

  20. Trends in gastric cancer mortality and in the prevalence of Helicobacter pylori infection in Portugal.

    Science.gov (United States)

    Morais, Samantha; Ferro, Ana; Bastos, Ana; Castro, Clara; Lunet, Nuno; Peleteiro, Bárbara

    2016-07-01

    Portugal has the highest gastric cancer mortality rates in Western Europe, along with high prevalences of Helicobacter pylori infection. Monitoring their trends is essential to predict the burden of this cancer. We aimed to quantify time trends in gastric cancer mortality in Portugal and in each administrative region, and to compute short-term predictions, as well as to describe the prevalence of H. pylori infection, through a systematic review. Joinpoint analyses were used to identify significant changes in sex-specific trends in gastric cancer age-standardized mortality rates (ASMR) and to estimate annual percent changes (APC). The most recent trends were considered to compute estimates up to 2020 by adjusting Poisson regression models. We searched PubMed and IndexRMP to identify studies carried out in Portugal reporting the prevalence of H. pylori. Gastric cancer mortality has been decreasing in Portugal since 1971 in men (from ASMR=55.3/100 000; APC=-2.4, 95% confidence interval: -2.5 to -2.3) and since 1970 in women (from ASMR=28.0/100 000; APC=-2.8, 95% confidence interval: -2.9 to -2.7), although large regional differences were observed. Predicted ASMR for 2015 and 2020 were 18.8/100 000 and 16.7/100 000 for men and 8.5/100 000 and 7.4/100 000 for women, respectively. The prevalence of H. pylori varied from almost 5% at 0.5-2 years to just over 90% at 70 years or more. No consistent variation was observed since the 1990s. The downward trends in mortality rates are expected to remain in the next decades. The high prevalence of H. pylori infection across age groups and studies from different periods shows a large potential for decrease in the burden of gastric cancer in Portugal.

  1. Evaluation of the level of depression among medical students from Poland, Portugal and Germany.

    Science.gov (United States)

    Seweryn, Mariusz; Tyrała, Kinga; Kolarczyk-Haczyk, Aleksandra; Bonk, Magdalena; Bulska, Weronika; Krysta, Krzysztof

    2015-09-01

    Depression is a serious illness affecting health, family and professional life of many people of all sectors of society. It also concerns students, regardless of their geographical location. The Beck Depression Inventory (BDI) is a proper tool to brief check of the level of depression because it has high correlation with depression. The aim of this study was to assess and compare the level of depression among medical students from Poland, Portugal and Germany. Students from different countries were asked to fill in an electronic form containing the BDI. The form was created separately for each country, using official translation of the BDI, approved by the competent psychiatric association. Google Drive software was used for the electronic form, and Stat soft Statistica v10 software for statistical analysis. There were statistically significant differences (p<0.05) in terms of average score of the BDI and of the proportion of the scores more than 10 points of medical and technology students among kinds of studies and countries. The average score of the BDI of medical students: Poland: 13.76±9.99 points; Germany: 8.49±7.64 points; Portugal: 7.37±7.67 points. The average score of the BDI of technology students: Poland: 12.42±9.66 points; Germany: 10.51±8.49 points; Portugal: 9.25±8.97 points. The proportion of the scores more than 10 points of medical students: Poland 56.32% (285/506) Germany 34.92% (154/441) Portugal 26.03% (82/315). The proportion of the scores more than 10 points of technology students: Poland 55.01% (368/669) Germany 43.82% (156/356) Portugal 37.57% (136/362). The highest depression score among medical and technology students according the BDI was found in Poland. A proper monitoring of depression is required, as well as rapid and appropriate help for those who suffer from it.

  2. Evolución histórica de la planeación de ciudades en Portugal

    Directory of Open Access Journals (Sweden)

    Carlos Balsas

    2006-12-01

    Full Text Available Este escrito refiere a la evolución de la planeación de ciudades en Portugal, con un énfasis especial en la revitalización del centro de la ciudad. Se identifican cinco períodos, los cuales son: el nacimiento de la planificación de ciudades (antes de 1820, la monarquía constitucional (1820- 1910, el régimen de dictadura (1926-1974, el"tercer movimiento" (1974-1985 y la fase de unión europea (1985-2003. Se argumenta que, a pesar de no haber un lapso directo correspondiente entre desarrollos históricos, los cuatro mayores movimientos internacionales _embellecimiento de la ciudad, renovación de la ciudad, ciudad empresarial y ciudad creativa y sustentable_ todos ellos hicieron su inicio en PortugalThis paper discusses the evolution of city planning in Portugal with a special emphasis on revitalization of city centre. Five periods are identified as: the birth of city planning (before 1820, the constitutional monarchy (1820-1910, the dictatorship regime (1926-1974, the `third wave' (1974-1985, and the European Union phase (1985-2003. I argue that even although there may not be direct temporal correspondence between historic developments, the four major international movements of the city beautiful, urban renewal, urban enterprise, and the sustainable and creative city all made their debut in Portugal

  3. Comparing flood mortality in Portugal and Greece under a gender and age perspective

    Science.gov (United States)

    Pereira, Susana; Diakakis, Michalis; Deligiannakis, Georgios; Luís Zêzere, José

    2017-04-01

    Flood mortality is analyzed and compared between Portugal and Greece. Flood fatality incidents are explored and compared in terms of their temporal evolution, spatial distribution, deadliest flood types, surrounding environments, gender and age of the victims. A common flood fatalities database for the period 1960-2010 was formed by merging the DISASTER database for Portugal and the Greek database previously built from documental sources. Each entry of the database, corresponding to a flood fatal incident has the following attributes: (i) ID number of the flood case; (ii) the flood type (riverine flood, flash flood, urban flood, or not defined type); (iii) date (day-month-year); (iv) location (x and y coordinates); (v) number of fatalities; (vi) surrounding environment where the flood fatal incident occurred (i.e. outdoors on foot, outdoors inside a vehicle, or inside a building). (vii) gender of the victim (male, female, or gender not reported); (viii) age of the victim (65 years). Excluding the outlier 1967 flash flood event occurred in the Lisbon metropolitan area that caused 522 fatalities, Portugal recorded 114 flood fatalities (related to 80 flood cases) and Greece registered 189 fatalities (related to 57 flood cases). Results identified decreasing mortality trend in both countries, despite some fluctuations irregularly distributed over time. Since the 1980's the number of flood cases with multiple fatalities has been gradually decreasing. In both Greece and Portugal flash floods were responsible for more than 80% of flood mortality and the main metropolitan areas of each country (Athens and Lisbon) presented a clustering of fatalities, attributed to the higher population density combined with the presence of flood-prone areas. Indoor fatalities have been gradually reducing with time, whereas vehicle-related deaths have been rising in both countries. In both countries the majority of flood victims are males, indicating that males are more vulnerable to fatal

  4. Weather types and the regime of wildfires in Portugal

    Science.gov (United States)

    Pereira, M. G.; Trigo, R. M.; Dacamara, C. C.

    2009-04-01

    An objective classification scheme, as developed by Trigo and DaCamara (2000), was applied to classify the daily atmospheric circulation affecting Portugal between 1980 and 2007 into a set of 10 basic weather types (WTs). The classification scheme relies on a set of atmospheric circulation indices, namely southerly flow (SF), westerly flow (WF), total flow (F), southerly shear vorticity (ZS), westerly shear vorticity (ZW) and total vorticity (Z). The weather-typing approach, together with surfacemeteorological variables (e.g. intensity and direction of geostrophic wind, maximum and minimum temperature and precipitation) were then associated to wildfire events as recorded in the official Portuguese fire database consisting of information on each fire occurred in the 18 districts of Continental Portugal within the same period (>450.000 events). The objective of this study is to explore the dependence of wildfire activity on weather and climate and then evaluate the potential of WTs to discriminate among recorded wildfires on what respects to their occurrence and development. Results show that days characterised by surface flow with an eastern component (i.e. NE, E and SE) account for a high percentage of daily burnt area, as opposed to surface westerly flow (NW, W and SW), which represents about a quarter of the total number of days but only accounts for a very low percentage of active fires and of burnt area. Meteorological variables such as minimum and maximum temperatures, that are closely associated to surface wind intensity and direction, also present a good ability to discriminate between the different types of fire events.. Trigo R.M., DaCamara C. (2000) "Circulation Weather Types and their impact on the precipitation regime in Portugal". Int J of Climatology, 20, 1559-1581.

  5. Dental radiographic exposures in Portugal

    International Nuclear Information System (INIS)

    Carvalho, A.F.; Oliveira, A.D.; Amaral, E.M.; Carreiro, J.V.; Galvao, J.P.

    1992-01-01

    A survey of dental intra-oral radiography was carried out in Portugal in 1989 and 1990 in hospitals, clinics and private offices. About 25% of the operational X ray units were checked. A total of 847 x 10 3 films were estimated as having been performed in 1989 corresponding to a frequency of 86 films per 10 3 inhabitants, which amounts to about 12% of all radiological examinations. The median entrance absorbed dose for a molar tooth was calculated to be 6.3 mGy but 85% of measured doses were out of acceptable dose range for good practice. Improvement of image quality and reduction of patient dose can be mainly achieved by improving the quality of film processing

  6. Depression and unemployment incidence rate evolution in Portugal, 1995-2013: General Practitioner Sentinel Network data.

    Science.gov (United States)

    Rodrigues, Ana Paula; Sousa-Uva, Mafalda; Fonseca, Rita; Marques, Sara; Pina, Nuno; Matias-Dias, Carlos

    2017-11-17

    Quantify, for both genders, the correlation between the depression incidence rate and the unemployment rate in Portugal between 1995 and 2013. An ecological study was developed to correlate the evolution of the depression incidence rates estimated by the General Practitioner Sentinel Network and the annual unemployment rates provided by the National Statistical Institute in official publications. There was a positive correlation between the depression incidence rate and the unemployment rate in Portugal, which was significant only for males (R2 = 0.83, p = 0.04). For this gender, an increase of 37 new cases of depression per 100,000 inhabitants was estimated for each 1% increase in the unemployment rate between 1995 and 2013. Although the study design does not allow the establishment of a causal association between unemployment and depression, the results suggest that the evolution of unemployment in Portugal may have had a significant impact on the level of mental health of the Portuguese, especially among men.

  7. HLA genes in Madeira Island (Portugal) inferred from sequence-based typing: footprints from different origins.

    Science.gov (United States)

    Spínola, Hélder; Bruges-Armas, Jácome; Mora, Marian Gantes; Middleton, Derek; Brehm, António

    2006-04-01

    Human leukocyte antigen (HLA)-A, HLA-B, and HLA-DRB1 polymorphisms were examined in Madeira Island populations. The data was obtained at high-resolution level, using sequence-based typing (SBT). The most frequent alleles at each loci were: A*020101 (24.6%), B*5101 (9.7%), B*440201 (9.2%), and DRB1*070101 (15.7%). The predominant three-loci haplotypes in Madeira were A*020101-B*510101-DRB1*130101 (2.7%) and A*010101-B*0801-DRB1*030101 (2.4%), previously found in north and central Portugal. The present study corroborates historical sources and other genetic studies that say Madeira were populated not only by Europeans, mostly Portuguese, but also sub-Saharan Africans due to slave trade. Comparison with other populations shows that Madeira experienced a stronger African influence due to slave trade than Portugal mainland and even the Azores archipelago. Despite this African genetic input, haplotype and allele frequencies were predominantly from European origin, mostly common to mainland Portugal.

  8. High relative frequency of thyroid papillary carcinoma in northern Portugal.

    Science.gov (United States)

    Sambade, M C; Gonçalves, V S; Dias, M; Sobrinho-Simões, M A

    1983-05-01

    Two hundred and twelve papillary and 40 follicular carcinomas were found in 3002 thyroid glands examined from 1931 to 1975 in four Laboratories of Pathology that fairly cover northern Portugal. There was a striking preponderance of women both in papillary (female:male = 6.9:1) and follicular carcinoma (5.7:1). Sex-specific frequency of malignancy was significantly greater in men (13.3%) than in women (8.8%). The overall papillary/follicular ratio was 5.3:1 and did not significantly change throughout the study period. Papillary/follicular ratio was not significantly greater in litoral (5.5:1) than in regions with a low iodine intake and a relatively high prevalence of goiter (3.5:1). It is advanced that this high relative frequency of papillary carcinoma in northern Portugal, even in goiter areas, may reflect the existence of a racial factor since there is not enough evidence to support the influence of dietary iodine, previous irradiation and concurrent thyroiditis.

  9. Prospective application of municipal solid wastes for energy production in Portugal

    International Nuclear Information System (INIS)

    Teixeira, Sandra; Monteiro, Eliseu; Silva, Valter; Rouboa, Abel

    2014-01-01

    Municipal solid waste (MSW) collection and disposal is a major urban environment issue in the world today. MSW management solutions have to be technologically feasible, legally and socially acceptable and environmentally and financially sustainable. European policy is pushing for a rational management of natural resources; a promising technological perspective today is waste valorisation, a process that involves sorting at the source, combined with material recycling and waste-to-energy conversion. In this paper, we analyze the evolution of the Portuguese MSW management system, criticize the environmental policy issues for MSW management in Portugal and identify weak points in the criteria used for the technologies selection. Portugal is facing multiple problems with MSW management and is attempting to tackle them by passing legislation in order to improve the performance of waste management systems. At the technological level, gasification increasingly presents as an efficient and viable alternative to incineration. Gasification is a waste-to-energy conversion scheme that offers an attractive solution to both waste disposal and energy problems. Waste gasification by plasma has been validated but the economic viability of this technology must be proven before to be accepted by the industry. - Highlights: • MSW collection and disposal are a major problem of urban environment. • Portugal is facing multiple problems and improving the MSW management system. • Gasification offers the most attractive solution to both waste disposal and energy problems. • Plasma gasification seems to be validated but the economic viability must be proven

  10. Salud y Seguridad del Trabajo en Portugal: apuntes diversos Some annotations about Occupational Health and Safety in Portugal

    Directory of Open Access Journals (Sweden)

    António de Sousa Uva

    2009-03-01

    Full Text Available El autor aborda algunos aspectos relativos a la Salud y Seguridad del Trabajo (SST en Portugal llamando la atención para, esencialmente, intentar sostener la tesis de que, desde mediados de la década de los 90, se observaron importantes avances en la mejoría de las condiciones del trabajo en la perspectiva de la SST, aunque se mantuvieron algunos problemas en la práctica concreta de las normativas legales. Incluso con estas mejoras, las tasas de frecuencia de accidentes de trabajo y de enfermedades profesionales en Portugal todavía se mantienen muy elevadas necesitando, por tanto, estrategias más "agresivas" para concienciar la sociedad portuguesa en torno a las políticas públicas de SST efectivamente promotoras de prevención de riesgos profesionales y de la promoción de la salud de quien trabaja. Es por tanto indispensable que la protección de la salud y de la seguridad de los trabajadores en los puestos de trabajo sea encarada como un conjunto de actividades de indiscutible utilidad para todos los representantes del mundo del trabajo e que la agenda política pase a valorizar, aún más, la promoción de espacios de trabajo saludables y seguros, con la consecuente valorización de las variables individuales en la estrategia nacional de salud y seguridad.In the present work, the author analyzes several aspects of Occupational Health and Safety (OHS in Portugal. He provides evidence sustaining the assumption of an important progress, since the mid-nineties, in the improvement of the working conditions from an OHS perspective. Nevertheless, several problems still remain in the practical application of legal regulations. In addition, despite of these improvements, the frequency rates of working accidents and occupational diseases remain very high. Hence, more "aggressive" strategies are required to increase the awareness of the Portuguese society relative to the OHS public policies, whose effectiveness has been demonstrated either in

  11. Multi-small molecule conjugations as new targeted delivery carriers for tumor therapy

    Directory of Open Access Journals (Sweden)

    Shan L

    2015-09-01

    Full Text Available Lingling Shan,1 Ming Liu,2 Chao Wu,1 Liang Zhao,1 Siwen Li,3 Lisheng Xu,1 Wengen Cao,1 Guizhen Gao,1 Yueqing Gu3 1Institute of Pharmaceutical Biotechnology, School of Biology and Food Engineering, Suzhou University, Suzhou, People’s Republic of China; 2Department of Biology, University of South Dakota, Vermillion, SD, USA; 3Department of Biomedical Engineering, School of Life Science and Technology, China Pharmaceutical University, Nanjing, People’s Republic of China Abstract: In response to the challenges of cancer chemotherapeutics, including poor physicochemical properties, low tumor targeting ability, and harmful side effects, we developed a new tumor-targeted multi-small molecule drug delivery platform. Using paclitaxel (PTX as a model therapeutic, we prepared two prodrugs, ie, folic acid-fluorescein-5(6-isothiocyanate-arginine-paclitaxel (FA-FITC-Arg-PTX and folic acid-5-aminofluorescein-glutamic-paclitaxel (FA-5AF-Glu-PTX, composed of folic acid (FA, target, amino acids (Arg or Glu, linker, and fluorescent dye (fluorescein in vitro or near-infrared fluorescent dye in vivo in order to better understand the mechanism of PTX prodrug targeting. In vitro and acute toxicity studies demonstrated the low toxicity of the prodrug formulations compared with the free drug. In vitro and in vivo studies indicated that folate receptor-mediated uptake of PTX-conjugated multi-small molecule carriers induced high antitumor activity. Notably, compared with free PTX and with PTX-loaded macromolecular carriers from our previous study, this multi-small molecule-conjugated strategy improved the water solubility, loading rate, targeting ability, antitumor activity, and toxicity profile of PTX. These results support the use of multi-small molecules as tumor-targeting drug delivery systems. Keywords: multi-small molecules, paclitaxel, prodrugs, targeting, tumor therapy

  12. Una historia de diseño del cartel en Portugal del siglo XVII al XIX

    OpenAIRE

    María Helena Ferreira Braga Barbosa

    2017-01-01

    To write an history of the design of the poster about three centuries in Portugal allows to understand how this artefact has changed over time. Usually, the result does not configure the reasons that gave rise of the poster, because they are not always visible and so, they don’t illustrate the reality in which they emerged. This article reveals a series of factors associated not only with the historical events, as well the adjacent constraints to design a poster. Portugal has in some cases...

  13. Prevalencia del Sobrepeso y de la Obesidad Infantil en Portugal.Programa MUNSI de Base Municipal

    OpenAIRE

    Rito, Ana; Silva, Ana Lúcia; Carvalho, Maria Ana; Ramos, Carlos; Breda, João

    2010-01-01

    INTRODUCIÓN: Hoy en día la prevalencia de obesidad infantil constituye uno de los problemas más serios de salud pública en Portugal. Estudios recientes demuestran que Portugal tiene una de las peores cifras de los paises de la Comunidad Europea. Hábitos alimentarios poco saludables relacionados con el consumo de alimentos de elevada densidad energética, principalmente en grasas saturadas y azúcares rápidos, asociados a bajos niveles de actividad física, surgen como los principales facto...

  14. Ecological survey of Saccharomyces cerevisiae strains from vineyards in the Vinho Verde Region of Portugal.

    Science.gov (United States)

    Schuller, Dorit; Alves, Hugo; Dequin, Sylvie; Casal, Margarida

    2005-01-01

    One thousand six hundred and twenty yeast isolates were obtained from 54 spontaneous fermentations performed from grapes collected in 18 sampling sites of three vineyards (Vinho Verde Wine Region in northwest Portugal) during the 2001-2003 harvest seasons. All isolates were analyzed by mitochondrial DNA restriction fragment length polymorphism (mtDNA RFLP) and a pattern profile was verified for each isolate, resulting in a total of 297 different profiles, that all belonged to the species Saccharomyces cerevisiae. The strains corresponding to seventeen profiles showed a wider temporal and geographical distribution, being characterized by a generalized pattern of sporadic presence, absence and reappearance. One strain (ACP10) showed a more regional distribution with a perennial behavior. In different fermentations ACP10 was either dominant or not, showing that the final outcome of fermentation was dependent on the specific composition of the yeast community in the must. Few of the grape samples collected before harvest initiated a spontaneous fermentation, compared to the samples collected after harvest, in a time frame of about 2 weeks. The associated strains were also much more diversified: 267 patterns among 1260 isolates compared to 30 patterns among 360 isolates in the post- and pre-harvest samples, respectively. Fermenting yeast populations have never been characterized before in this region and the present work reports the presence of commercial yeast strains used by the wineries. The present study aims at the development of strategies for the preservation of biodiversity and genetic resources as a basis for further strain development.

  15. Dinâmicas e processos de inovaçâo em regiôes do interior de Portugal: caso de estudo = Dynamics and processes of innovation in the interior regions of Portugal: a case study

    Directory of Open Access Journals (Sweden)

    Maria Manuela Natario

    2011-12-01

    between the helices to promote innovation. This empirical study includes three districts in Portugal (Castelo-Branco, Guarda and Viseu. The methodology consisted of a survey involving the companies in these districts and application of multivariate statistical analysis “k-means clusters” to detect their behavioral patterns within the region’s profile in terms of dynamics of innovation, spirit of business initiative, cooperation with the higher education institutions and proactivity of public institutions. In order to verify the formulated hypotheses, we resorted to the application of tests of multiple average differences to assess the unique characteristics of each cluster.O presente trabalho tem como objectivo analisar as dinâmicas e os processos de inovação em regiões do interior centro de Portugal, procurando identificar factores que estimulam a dinâmica territorial de inovação. A preocupação com as dinâmicas de inovação tem sido alvo de diversos estudos no âmbito dos sistemas regionais de inovação e mais recentemente tem sido enquadrada no desenvolvimento do Modelo “Triple Helix” (Leydesdorff e Etzkowitz, 2000; Dzisah e Etzkowitz, 2009. Este modelo integra o estudo da interacção entre as hélices para promover a inovação. O estudo empírico incide sobre as empresas de três distritos do interior centro de Portugal. Como metodologia foi realizado um questionário às empresas destes distritos e utilizou-se a aplicação da análise estatística multivariada “k-means clusters” para detectar padrões comportamentais das empresas relativamente à sua dinâmica de inovação e face ao perfil da região em termos de inovação, espírito de iniciativa empresarial, cooperação com as IES e proactividade das Instituições Públicas. Para verificar as hipóteses formuladas recorremos à aplicação de testes de diferenças múltiplas de médias para aferirmos as características únicas de cada cluster.

  16. Infeção por staphylococcus aureus meticilina-resistente da comunidade em Portugal

    Directory of Open Access Journals (Sweden)

    R. Nazareth

    2012-01-01

    Full Text Available Resumo: Recentemente assistiu-se à emergência de infeções na comunidade por Staphylococcus aureus meticilina-resistente (MRSA em indivíduos sem fatores de risco. O MRSA associado à comunidade (CA-MRSA parece ser mais virulento, causando desde infeções superficiais da pele e tecidos moles até fasceíte necrosante e, raramente, pneumonia.O CA-MRSA foi inicialmente identificado na Austrália no início da década de 80 e, após cerca de duas décadas, surgiu nos EUA e em vários países da Europa, Ásia e América do Sul. Não existe informação disponível acerca da prevalência em Portugal.Os autores reportam o primeiro caso de infeção por CA-MRSA em Portugal, num adulto jovem com pneumonia necrotizante grave complicada por empiema bilateral e insuficiência respiratória. Abstract: Methicillin-resistant Staphylococcus aureus (MRSA has recently emerged as a cause of community-acquired infections among individuals without risk factors. Community-associated MRSA (CA-MRSA appears to be more virulent, causing superficial mild skin and soft tissue infections to severe necrotizing fasciitis, and in rare cases, pneumonia.Community-associated MRSA was first reported in Australia in the early 80s, after almost two decades in the USA, and then in several countries in Europe, Asia and South America. No data exists in Portugal.We report the first case of CA-MRSA infection in Portugal, in a young adult with severe necrotizing pneumonia, complicated with bilateral empyema and respiratory failure. Palavras-chave: comunidade associada, MRSA, Staphylococcus aureus, pneumonia necrosante, empiema, Keywords: Community-associated, MRSA, Staphylococcus aureus, Necrotizing pneumonia, Empyema

  17. Deterministic tsunami hazard assessment of Sines - Portugal

    OpenAIRE

    Wronna, Martin

    2015-01-01

    Tese de mestrado em Ciências Geográficas, apresentada à Universidade de Lisboa, através da Faculdade de Ciências, 2015 Neste trabalho apresenta-se uma abordagem determinística de perigo de tsunamis considerando múltiplas fontes para a cidade costeira de Sines, Portugal. Tsunamis ou maremotos são eventos extremos, energeticamente elevados mas pouco frequentes. Normalmente são geradas por um deslocamento duma grande quantidade de água seja por erupções vulcânicas, colapso de caldeiras, desli...

  18. Modelling post-fire vegetation recovery in Portugal

    OpenAIRE

    A. Bastos; C. M. Gouveia; C. C. DaCamara; R. M. Trigo

    2011-01-01

    Wildfires in Mediterranean Europe have been increasing in number and extension over the last decades and constitute one of the major disturbances of these ecosystems. Portugal is the country with more burnt area in the last decade and the years of 2003 and 2005 were particularly devastating, the total burned areas of 425 000 and 338 000 ha being several times higher than the corresponding average. The year of 2005 further coincided with one of the most severe droughts since early 20th century...

  19. Genetic characterization of Toxoplasma gondii isolates from Portugal, Austria, and Israel reveals higher genetic variability within the type II lineage

    Science.gov (United States)

    This study compared genetic diversity of Toxoplasma gondii isolates from Portugal, Austria and Israel. For this, we genotyped 90 T. gondii isolates (16 from Portugal, 67 from Austria and 7 from Israel) using 10 nested PCR-restriction length polymorphism (RFLP) genetic markers and 15 microsatellite (...

  20. Portugal and South Africa: Close Allies or Unwilling Partners in ...

    African Journals Online (AJOL)

    The popular perception of the existence of a straightforward alliance between Portugal and South Africa as a result of the growing efficacy of African nationalist groups during the 1960s and early 1970s has never been seriously questioned. However, new research into recently declassified documents from the Portuguese ...

  1. Estudo de dois mapas do geógrafo Robert de Vaugondy relativos ao Reino de Portugal do Século XVIII (1751

    Directory of Open Access Journals (Sweden)

    Marco Pais Neves dos Santos

    2013-07-01

    Full Text Available Analisamos dois mapas alusivos ao reino de Portugal, datados de 1751, publicados em Paris e assinados pelo geógrafo Robert de Vaugondy, a saber: Partie Septentrionale du Royaume de Portugal, par le Sr. Robert, Geographe ordinaire du Roy. Avec Privilege. 1751. e Partie Meridionale du Royaume de Portugal, par le Sr. Robert, Geographe ordinaire du Roy. Avec Privilege. 1751., com o objetivo de propor uma explicação para as divisões administrativas cartografadas. Como suporte ao objeto do trabalho, caracterizamos de forma concisa a evolução dos limites administrativos do reino de Portugal, desde a sua formação até a atualidade, e abordamos a vida e obra de Robert de Vaugondy. Concluímos ser o mais consentâneo com a lógica representarem divisões eclesiásticas.

  2. High altitude Chironomidae (Diptera of Serra da Estrela (Portugal: Additions to the Portuguese and Iberian Peninsula fauna

    Directory of Open Access Journals (Sweden)

    Rieradevall, M.

    2007-12-01

    Full Text Available A Chironomidae (Diptera fauna list for headwater streams of high altitude areas in Serra da Estrela (Portugal is presented, doubling the previously established species richness for the region. The findings include 17 new records for Portugal, which represent an increase to 219 species for the Continental Portugal Chironomidae fauna. Two new records were detected for the Iberian Peninsula: one species (Tvetenia duodenaria, and one subgenus –Psectrocladius (Mesopsectrocladius–; and the presence of the genus Natarsia is confirmed. The last two occurrences correspond to monoespecific taxa of the Palearctic region. However, as taxonomic identification has been based on larval material, instead of pupae, pupal exuviae or imagoes, species level assignment is still uncertain.

    Se presenta una lista de especies de Chironomidae (Diptera recolectadas en los ríos de cabecera de zonas de alta montaña en la Serra da Estrela (Portugal. Con esta aportación se duplica la riqueza de especies regional conocida hasta el momento y se eleva la fauna de quironómidos del Portugal continental a 219 especies. Se incluyen dos nuevas citas para la Península Ibérica, una especie (Tvetenia duodenaria y un subgénero –Psectrocladius (Mesopsectrocladius–, y se confirma la presencia del género Natarsia. En los dos últimos casos se trata de larvas de taxones hasta el momento monoespecíficos en la región paleárctica, pero al no haberse recolectado pupas o adultos no se puede asegurar la identificación específica.

  3. Using Choice Experiments to Assess Environmental Impacts of Dams in Portugal

    Directory of Open Access Journals (Sweden)

    Anabela Botelho

    2015-08-01

    Full Text Available Despite their well-known benefits in electricity production, dams are also responsible for some adverse environmental impacts affecting particularly the wellbeing of residents of the local communities. These environmental damages have not been included in the cost-benefit analysis of hydropower developments mainly because of the difficulty to determine their value. The prime objective of this paper is to measure the economic values of several environmental impacts due to the dams' activity in Portugal, using a discrete choice experiments approach. With the results of this research paper, we expect to contribute to a more efficient and thorough cost-benefit analysis within the complex process of deciding the optimal location of future dams to be built not only in Portugal, but elsewhere. The addition of this stage to the decision-making process allows the integration of economic, social and environmental dimensions, promoting a richer and more informed decision process.

  4. Air quality management in Portugal: example of needs and available tools.

    Science.gov (United States)

    Borrego, C; Miranda, A I; Coutinho, M; Ferreira, J; Carvalho, A C

    2002-01-01

    The Framework Directive (FWD) and the proposed Daughter Directives are the newest legislative instruments concerning a new political strategy and air quality management approach for Europe. Additionally, the member countries of the United Nations Economic Commission for Europe have included the concepts of critical load and level for planning air pollution abatement strategies and as a base of international agreements concerning limitation of the emissions of air pollutants. These concepts imply an accurate knowledge about pollutants deposition fluxes. The paper describes the main needs and the tools available to define a strategy of air quality management in Portugal. Two study cases are presented: (1) extensive monitoring plan to assess the impact of an urban incinerator plant; and (2) contribution to a methodology to estimate critical levels for a coastal region in Portugal. These different approaches allowed illustrating the complexity of the implementation of an air pollution management strategy.

  5. Corporate Blended Learning in Portugal: Current Status and Future Directions

    Science.gov (United States)

    Marcal, Julia; Caetano, Antonio

    2010-01-01

    The aim of this study is to characterize the current status of blended learning in Portugal, given that b-learning has grown exponentially in the Portuguese market over recent years. 38 organizations (representing 68% of all institutions certified to provide distance training by the Government Labour Office--DGERT-) participated in this study. The…

  6. Regional thermal patterns in Portugal using satellite images (NOAA AVHRR

    Directory of Open Access Journals (Sweden)

    António Lopes

    1995-06-01

    Full Text Available In this paper two NOAA AVHRR diurnal images (channel 4 are used to determine the required procedures aiming at a future operational analysis system in Portugal. Preprocessing and classification operations are described. Strong correlation between air and surface temperature is verified and rather detailed air temperature patterns can be inferred.

  7. Portugal's war in Angola 1961-1974 | Van Dar Waals | Scientia ...

    African Journals Online (AJOL)

    Scientia Militaria: South African Journal of Military Studies. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 23, No 4 (1993) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register. Portugal's war in Angola 1961- ...

  8. A New Pilgrimage in Portugal: Following the Steps of Saint Nuno

    Directory of Open Access Journals (Sweden)

    Carla Braga

    2013-12-01

    Full Text Available Tourism is an ever-changing reality. Pilgrimages need different stimuli to attract new followers. In this context we propose to create an itinerary following the steps of Saint Nuno of Santa Maria, canonized in 2009. Nuno Álvares Pereira was the real name of Saint Nuno, who was granted the title Constable of Portugal, and became a historic legend in the independence wars of Portugal during the political crisis of 1383-1385. After fighting against the power of Castile (Spain he decided to devote his life to religion as a Carmelite Friar. He represents the perfect hero of the Middle Ages - associating military prowess with a religious character. Our proposal is to create a religious itinerary based on facts of Saint Nuno’s life, so that any visitor may easily discover the country following the steps of this saint who was deeply devoted to the Virgin - in fact, all temples he founded and restored were dedicated to Our Lady. One of his most famous foundations is the Carmelite Convent in Lisbon, which long after his death was an outstanding popular pilgrimage place, and today is still a strong visitor attraction. This exploratory study is based on literature review and text analyses about religious tourism, itinerary design and the life of the saint. The fieldwork includes acknowledging the different sites related to the saint. We believe that it is possible to create an original religious itinerary in Portugal, which will attract not only foreigners but also domestic visitors, increasing the ‘Production and Consumption of the Pilgrimage Tourism Experience’.

  9. Is kenaf an effective land-use alternative for the energy and industrial sectors in Portugal?

    Energy Technology Data Exchange (ETDEWEB)

    Fernando, A.; Morais, J.; Mendes, B.; Oliveira, J.F.S. [Grupo de Disciplinas de Ecologia da Hidrosfera, Unidate de Biotecnologia Ambiental, Faculdade de Ciencis e Tecnologia da Universidade Nova de Lisboa, Caparica (Portugal)

    2008-07-01

    The overall objective of this work was to evaluate kenaf as a non-food crop through an integrated approach for alternative land use in Portugal that will provide diversified opportunities for farmers and biological materials for the bio-based industries of the future. Results show that kenaf appears to represent an efficient land-use alternative in Portugal. At the pedoclimatic conditions of South Portugal, high yields can be achieved (28 t dry matter.ha-1.year-1), depending on the applied cultivation techniques. The time of sowing and the level of irrigation are the main crop management factors that affect biomass yields. Benefits of this crop relies not only on the possibility of its use as a renewable raw material for energy and industrial purposes but also on the possibility to make good use of set aside land or even derelict land, limiting erosion risks. Detailed consideration of the energy balances suggests that the use of kenaf-fibres for the production of thermal insulation boards are favored over its use as an energy feedstock, where energy balances may be poor.

  10. Ciudadanía transnacional: latinoamericanos en Portugal

    OpenAIRE

    Padilla, Beatriz; Ortiz Scaglione, Alejandra

    2014-01-01

    Este artículo reflexiona sobre el ejercicio de la ciudadanía como consecuencia de la migración internacional, aplicado al caso de los latinoamericanos residentes en Portugal. Para ello adoptamos el concepto de ciudadanía transnacional por su maleabilidad, ya que permite considerar la perspectiva conjunta de los países de origen y de destino, así como también la influencia de las relaciones binacionales e internacionales. Nos preguntamos cómo se ejerce la ciudadanía transnacional en los espaci...

  11. Current status of nucleonic gauges in Portugal

    International Nuclear Information System (INIS)

    Salgado, J.; Carvalho, F.G.; Manteigas, J.; Oliveira, C.; Goncalves, I.F.; Neves, J.; Cruz, C.

    2000-01-01

    The nucleonic gauges are largely used in Portugal industry, despite the fact that design and manufacturing of prototypes of nucleonic gauges is rather limited. The modernization of some industrial sectors (cement, paper and civil engineering) has enhanced applications of nucleonic gauges and has created local capability but new legislation tends to restrict further spread of them. The Institute of Nuclear Technology is the only applied research institution developing nucleonic gauges for moisture, thickness and density, and elemental analysis, as well as providing assistance in calibration, safe operation and maintenance of them. (author)

  12. Hybrid modeling to support energy-climate policy: Effects of feed-in tariffs to promote renewable energy in Portugal

    International Nuclear Information System (INIS)

    Proença, Sara; St Aubyn, Miguel

    2013-01-01

    Feed-in tariffs have been the main policy instrument applied in Portugal for the promotion of electricity produced from renewable energy sources under the EU Directives on energy and climate regulation. In this paper, we provide an empirical impact assessment of the economic and environmental effects of Portugal's FITs policy to promote RES-E generation. Impact assessment of policy instruments plays a crucial role on decision-making process. For numerical simulations, we make use of a hybrid top-down/bottom-up general equilibrium modeling approach, which represents a reliable tool to analyze the complex interactions between economic, energy, and environmental issues related to energy policies. Numerical simulations confirm the empirical evidence that the FITs policy implemented by Portugal was both an effective and a cost-efficient way to increase the generation of electricity from renewable energy sources and thus to achieve the national RES-E target of 45% in 2010. Results show relatively modest macroeconomic impacts indicating potentially low economic adjustment costs. From an environmental perspective, the deployment of renewable energy source results in significant carbon emissions reductions. - Highlights: ► We provide an impact assessment of Portugal's FITs policy to promote RES-E generation. ► For numerical simulations, we make use of a hybrid top-down/bottom-up general equilibrium model. ► Portugal's FITs policy proved to be a cost-efficient way to increase generation of renewable electricity. ► Results show relatively modest macroeconomic effects indicating potentially low economic adjustment costs. ► The deployment of renewable energy sources results in significant carbon emission reductions

  13. O uso das redes sociais por jornalistas em Portugal

    Directory of Open Access Journals (Sweden)

    Ana Sofia Veloso

    2015-03-01

    Full Text Available Este artigo pretende mostrar como as redes sociais são utilizadas pelosjornalistas, nomeadamente os que trabalham em Portugal. É ainda intuito deste trabalho perceber se o uso destas ferramentas por estes profissionais pode constituir uma nova prática rotineira.Para o efeito, levou-se a cabo um estudo de carácter exploratório baseado nos resultados de um inquérito por questionário – realizado de raiz – dirigido à classe jornalística em Portugal. O artigo divide-se em quatro partes. Tendo em conta que, em pouco mais de uma década, as redes sociais se tornaram a atividade online mais popular a nível global, começa-se por realizar um enquadramento de apoio ao surgimento destas ferramentas na sociedade atual, dando conta de algumas estatísticas de uso e de novos processos de socialização subsequentes. Num segundo momento, é feito refereência à relação do jornalismo com as redes sociais e algumas novas práticas jornalísticas neste âmbito, apresentando conclusões de estudos internacionais sobre a utilização que jornalistas de diversos países fazem das redes sociais. Aborda-se ainda as orientações existentes sobre o uso ético que os jornalistas devem dar a estas ferramentas segundo várias entidades ligadas ao universo do jornalismo. A terceira parte foca-se no inquérito, designadamente a metodologia usada e a estrutura do mesmo; realiza-se um breve retrato sociográfico da classe jornalística em Portugal e faz-se uma caracterização socioprofissional da amostra obtida através do inquérito; apresentam-se os resultados conseguidos e analisam-se e discutem-se os mesmos, nomeadamente através de comparações com as estatísticas e as conclusões dos estudos nacionais e internacionais já mencionadas. Na quarta secção, tendo por base a discussão realizada e o balanço do tratamento do inquérito, menciona-se alguns desafios que se colocam aos jornalistas na era da Web 2.0. E conclui-se com a confirmação de que a

  14. Training requirements for agro-food industry in Portugal

    OpenAIRE

    Pedro D. Gaspar; Rita Pinheiro; Cláudia Domingues; Celestino Almeida; Teresa Paiva; Carlos D. Pereira; Manuela Vaz-Velho

    2015-01-01

    Agro-food companies are aware that the technical and soft skills of their employees directly influence business performance and, consequently, improving those skills will enhance the effectiveness and efficiency of their companies. This paper presents the main results of the AgriTraining project “Training requirements for the agro-food industry". Activities in pursuit of the objectives of this project involved: (1) analysis of the training needs in the agro-food industry in Portugal; (2) anal...

  15. Pesquisa ambiental de agentes de esporotricose em Portugal

    OpenAIRE

    Dançante, Ana Mafalda da Silva Grilo Carreteiro

    2017-01-01

    A esporotricose é uma das principais micoses subcutâneas reportadas mundialmente. O agente etiológico é um complexo de espécies dimórficas relacionadas conhecido como complexo Sporothrix schenckii. Considerada uma doença rara na Europa, foi recentemente identificado um caso autóctone em Portugal. Este trabalho teve como principal objetivo, desenvolver um ensaio baseado em PCR para detetar e identificar membros do complexo S. schenckii em amostras ambientais, e realizar uma pesquisa ...

  16. The impact of minimum wages on youth employment in Portugal

    NARCIS (Netherlands)

    S.C. Pereira

    2003-01-01

    textabstractFrom January 1, 1987, the legal minimum wage for workers aged 18 and 19 in Portugal was uprated to the full adult rate, generating a 49.3% increase between 1986 and 1987 in the legal minimum wage for this age group. This shock is used as a ?natural experiment? to evaluate the impact of

  17. Occupational exposure in Portugal in the 1999 - 2003 period

    International Nuclear Information System (INIS)

    Martins, M.B.; Abrantes, J.N.; Alves, J.G.

    2006-01-01

    The annual effective doses evaluated by the Individual Monitoring Service of the Radiological Protection and Nuclear Safety Department (D.P.R.S.N.) of the Nuclear and Technological Institute (I.T.N.) in Portugal, in the 5-year period from 1999 - 2003, are analysed and presented in this paper. In this period, the I.M.S. at I.T.N.-D.P.R.S.N. monitored nearly 91% of all the monitored population in Portugal. In 2003, approximately 9,000 professionally exposed workers from 970 facilities spread from all over the country were monitored. The workers are organized in four fields of activity, namely conventional industry, research, medicine and mining. In the period from 1999 to 2003, the workers from the medical sector represented 80-85% of the monitored population. In Portugal there are no nuclear power plants but there is a nuclear research reactor at I.T.N. premises. People working at the reactor were included in the research field. In this period, the number of workers involved in the mining field decreased as the exploration of natural Uranium ore was gradually discontinued. During this period there were two monitoring systems operating at the I.M.S. of I.T.N.-D.P.R.S.N., one based on film and the other one based on thermoluminescence detectors (TLD). An effort was made to transfer people monitored by film to TLD and in 2003 nearly 6,500 workers (approx.) were monitored with this methodology. Workers shifted from film to TLD monitoring method were taken into account and considered only once. In this work, the annual whole body doses evaluated in the period 1999 to 2003 were considered. The distribution of workers in each field of activity was determined and the distribution of workers by dose intervals in each field is presented. The annual average doses were computed for the total monitored population and for the exposed workers in each field of activity. The annual collective doses in each field of activity and the total collective doses were also determined and

  18. THE SOCIAL PERCEPTION OF NATURAL HAZARDS RISK: PORTUGAL AND TUVALU

    Directory of Open Access Journals (Sweden)

    Rodrigo Rudge Ramos Ribeiro

    2012-01-01

    Full Text Available Los efectos del cambio climático y del nivel del mar deben causar graves problemas para los habitantes de algunas pequeñas islas como Tuvalu en el futuro. Como resultado de una combinación de procesos naturales y acción antropogénica, el cambio del nivel del mar genera un impacto diferente. Esta investigación aborda la percepción del riesgo natural y del cambio climático en Portugal y Tuvalu. La percepción de algunos riesgos naturales, como la subida del nivel del mar, puede ser distinta para cada sitio. La percepción de los cambios climáticos en Tuvalu es poco conocida por la comunidad académica de la Universidad de Aveiro, y creen que los impactos del aumento del nivel del mar para Portugal y Tuvalu no son los mismos. La distancia geográfica tiene una influencia en la percepción del riesgo, a mayor distancia se le da una menor atención.

  19. Pensar o homem como corpo: a cunhagem Simbólica em Portugal e Espanha (século 19 - Thinking man as body: symbolic coinage in Portugal and Spain (19th century

    Directory of Open Access Journals (Sweden)

    José Viegas Brás

    2014-05-01

    Full Text Available Neste artigo investigamos a construção do corpo pelos manuais de civilidade publicados em Portugal e em Espanha no século 19. Os manuais de civilidade constituíram um mecanismo de poder-saber disciplinador da burguesia em ascensão eque marcaram certo processo de subjectivação. A partir do corpo estabeleceu-se uma nova ordem, que elevou o orgânico ao funcional e simbólico, em sintonia com a classe burguesa em ascensão, e que buscou orientar cada indivíduo a constituir-se como um sujeito moral, dando-lhe distinção e prestígio.Palavras-chave: corpo, história, manuais, civilidade.THINKING MAN AS BODY: SYMBOLIC COINAGE IN PORTUGAL AND SPAIN (19TH CENTURYAbstractIn this paper, we study the construction of the body through civility course books published in Portugaland Spainin the 19th century. The civility course books were a mechanism of power-knowledge relationship disciplinary of the rising bourgeoisie which un le as he da certain process of subjectivity. From the body a new order was set up, which raised the organic to functional and symbolic-in line with the growing bourgeois class-and guide de ach individual to establish him/herself as a moral subject, giving him/her distinction and prestige.Key-words: body, history, manuals, civility.PENSANDO EN EL HOMBRE COMO CUERPO: INVENCIÓN SIMBÓLICAEN PORTUGAL Y ESPAÑA (SIGLO 19ResumenEn este trabajo, investigamos la construcción del cuerpo a través de los manuales de civilidad publicado en Portugal y en España en el siglo 19. Los manuales de civilidad eran un mecanismo de poder-saber disciplinador de la burguesía naciente que marcaron cierto proceso de subjetividad. Partiendo del cuerpo, si establece un nuevo orden que eleva el orgánico al funcional y simbólico, según la naciente burguesía, y que guío a cada individuo para constituirse como sujeto moral, dándole prestigio y distinción.Palabras-clave: cuerpo, historia, manuales, civilidad.PENSER L'HOMME COMME CORPS

  20. Fugitives in transit. The Spanish Republican exile through Portugal (1936-1950

    Directory of Open Access Journals (Sweden)

    Aurelio Velázquez Hernández

    2018-01-01

    Full Text Available Despite scant attention from historiography, Portugal played an important role as a way station on the road to exile for many Republicans during and after the Spanish Civil War. The situation in the neighbouring country was not easy for these people, as Antonio Oliveira de Salazar’s regime —officially allied with Franco’s Spain— did not recognize them as political refugees, but as illegal immigrants to be returned to Spain, which would have catastrophic consequences for many of them. Through the analysis of abundant primary sources in archives from Spain, Portugal, Mexico and the United States, we seek to understand the details of this Portuguese stage of the exile. We discover how, despite the official position of the Portuguese authorities, there were certain margins of ambiguity that allowed the departure of several thousand Spaniards to Mexico and other countries. Finally we study the fundamental intervention of international aid agencies like the Unitarian Service Committee.

  1. Antimicrobial, antiviral and antioxidant activities of "água-mel" from Portugal.

    Science.gov (United States)

    Miguel, Maria G; Faleiro, Leonor; Antunes, Maria D; Aazza, Smail; Duarte, Joana; Silvério, Ana R

    2013-06-01

    "Água-mel" is a honey-based product produced in Portugal for ancient times. Several attributes have been reported to "água-mel" particularly in the alleviation of simple symptoms of upper respiratory tract. Samples of "água-mel" from diverse beekeepers from different regions of Portugal were studied in what concerns antimicrobial, antioxidant and antiviral properties. The amounts of phenol and brown pigment were also evaluated and correlated with the antioxidant activities. A great variability on the levels of these compounds was found among samples which were responsible for the variability detected also on the antioxidant activities, independent on the method used. Generally, antioxidant activity correlated better with brown pigments' amount than with phenols' content. The antimicrobial activity found for "água-mel" samples confirm the virtues reported by popular findings. In addition, this work also reveals the antiviral properties of "água-mel" evidenced by a decrease on the infectivity of the Qβ bacteriophage. Copyright © 2013 Elsevier Ltd. All rights reserved.

  2. Factors Affecting Students' Choice of Science and Engineering in Portugal.

    Science.gov (United States)

    de Almeida, Maria Jose B. M.; Leite, Maria Salete S. C. P.; Woolnough, Brian E.

    This paper presents the results of a study undertaken in Portugal to determine the influence of different factors on students' (n=499) decisions to study or refuse to study in one of the physical sciences or engineering. Some influencing factors are related to what goes on in school and during science lessons, and other factors are related to the…

  3. Five new hypogean Occidenchthonius (Pseudoscorpiones: Chthoniidae) from Portugal

    DEFF Research Database (Denmark)

    Zaragoza, Juan A.; Reboleira, Ana Sofia

    2018-01-01

    Five new species of the recently created genus Occidenchthonius Zaragoza, 2017 are described from caves of Portugal: Occidenchthonius alandroalensis sp. nov., O. algharbicus sp. nov., O. duecensis sp. nov., O. goncalvesi sp. nov. and O. vachoni sp. nov. The species Occidenchthonius cardosoi (Zara...

  4. Geoconservation education: the leading role of the University of Minho (Portugal)

    Science.gov (United States)

    Brilha, J.; Pereira, D.; Pereira, P.

    2012-04-01

    The University of Minho (with two campuses in Braga and Guimarães, northern Portugal) is a middle-size university created in 1973 and today with around 18,000 students and 1,100 academic staff members. The first works concerning geoconservation were developed in 1996 in the Earth Sciences Department. The research was related with the inventory of geological heritage in Alvão Natural Park, under the scope of a master thesis on Environmental Sciences. But it was only in 2005 that a major step was taken by this university with the creation of the master course on Geological Heritage and Geoconservation. Since that time, around 70 students were enrolled with an average of 10 new students each year. This 2-years course (120 ECTS) is the only post-graduation degree totally dedicated to this domain. During the first year, students have to complete several multidisciplinary modules like: Geodiversity; GIS and computers applied to geoconservation; Inventorying, conservation and interpretation of geological heritage; Environmental legislation; Geotourism; Education for sustainable development; and Mining heritage. The second year is dedicated to the preparation of a dissertation or project. This experience on geoconservation education has been motivating internationalisation with other universities with the support of different grant programmes like Erasmus and AlBan (both from the European Union) and Gulbenkian (Portugal): Students exchange (to Brazil and Greece; from Argentina, Brazil, Cape Verde, Chile, Mozambique, and Thailand) and staff exchange (to/from Greece, Spain, Switzerland, Turkey, United Kingdom, and United States of America). After finishing their master degree, students are finding jobs as geoconservationist experts in geoparks, protected areas, natural history museums, and also as teachers in secondary schools and universities. The University of Minho is also engaged with geoconservation at the PhD level. Several theses have been produced focused of themes

  5. The paradox of EU enlargement and member states' policies: Dilemmas and challenges: The case of Portugal

    Directory of Open Access Journals (Sweden)

    Neves Santos Miguel

    2016-01-01

    Full Text Available The paper addresses the issue of EU enlargement with its dual nature: of an intra-EU process, related to the consolidation of a democratic-peace based on collective security, and an external process, involving EU foreign policy and impact on relations with other major global players. Although enlargement is a multidimensional process that combines different perspectives - candidate countries' enlargement politics, member states' politics/policy, EU enlargement politics and external global impact - the paper focuses on Member States policies towards enlargement by looking at the case of Portugal, in particular in relation with the Big Bang Eastern enlargement, and aims at explaining the paradox of Portugal's strong political support to enlargement while it was one of the main potential losers in terms of economic interests. A 'foreign policy analysis' framework is adopted in order to understand the process of decision-making and the interaction between the domestic and the EU levels. The argument put forward is that an exclusive constructivist approach does not provide a satisfactory explanation, as there was also rationalist-interest logic at play. The Portuguese policy towards enlargement was determined not only by the 'solidaritysimilarity' logic, dominant in the formal political discourse but also by the consideration of long-term interests in the EU related to the preservation of the strategic alliance with Germany. The overall systemic impact of enlargement tends to weaken the EU as it presents a major paradox functioning as a double-edged sword. While it has a positive impact by contributing to the enhancement of the EU international profile as it grows in size raising expectations about its potential global role, it also leads to greater heterogeneity, undermining the EU cohesion and its ability to act together with a single voice becoming a robust global player, thus frustrating the expectations raised in the first place.

  6. La expulsión de los jesuitas de Portugal en la “era pombalina”

    Directory of Open Access Journals (Sweden)

    Vivanco Díaz, Borja

    2014-04-01

    Full Text Available The Jesuits were expelled from Portugal in 1759 as a consequence of Regalian policy of enlightened despotism, which had been wholeheartedly accepted by Marquis of Pombal, prime-minister under the King Joseph I. Accusations of inciting the Guarani people to rise up against “The Treaty of the borders”, on the one hand, and of conspiring in the assassination attempt against King Joseph I, on the other, supported the decision to force the Jesuits into exile. However, neither allegation has been ever proven, rather they were the result of Pombal’s campaign against Saint Ignatius of Loyola’s order. The ultimate outcome of the expulsion of the Jesuits was the diminished influence of Catholic Church, thus encourating the introduction of new Enlightenment ideas in Portugal.Los jesuitas fueron expulsados de Portugal en 1759 como consecuencia de la política “regalista” del “despotismo ilustrado” y a la que se había adherido sin reservas el Marqués de Pombal, primer ministro del rey José I. Las acusaciones de instigar a los guaraníes a rebelarse contra el Tratado de los Límites, por un lado, y de conspirar en la organización del atentado frustrado contra la vida de José I, por otro, sirvieron de argumentos para provocar el exilio de la Compañía de Jesús. Sin embargo, ninguna de las dos acusaciones ha podido ser nunca probada y respondieron más bien a la campaña “pombalina” contra la orden de Ignacio de Loyola. Como resultado final, la expulsión de los jesuitas aminoró la influencia de la Iglesia Católica y favoreció la introducción en Portugal de las nuevas ideas de la Ilustración.

  7. Imprensa, escola e a forma da leitura em Portugal no século 19

    Directory of Open Access Journals (Sweden)

    Carlota Boto

    2012-06-01

    Full Text Available  Este trabalho procura abordar a situação da educação e particularmente da escola primária em Portugal na primeira metade do século 19, à luz do olhar que a imprensa tinha da mesma escolarização. Parte-se da interpretação do discurso educacional que à época seria assumido particularmente por um setor específico da imprensa, constituído por revistas e periódicos que tinham intenção de esclarecimento e instrução das populações. Tais revistas propunham, portanto, o investimento social na escola primária como uma maneira de reconstituir uma dada vocação perdida da nacionalidade portuguesa. De alguma maneira, tratava-se de inserir Portugal na desejada modernidade, mediante a criação do rito escolar, ou daquilo que já se caracterizou por forma escolar de socialização.  Abstract This paper looks for approaching the education situation and, in particular, of the primary school in Portugal during the first half of the 19th century, coming to light the way of thinking that the press had about the same act of schooling. Starting from the interpretation of the educational discourse that, in that epoch, would be assumed, in particular, by a specific sector of the press, constituted by magazines and periodicals wich had the intention of clearness and instruction of the populations. Such magazines were proposing, consequently, the social investiment in the primary school as a manner to rebuild the inborn lost vocation of the portuguese nationality. In any way, the objective was to introduce Portugal in the desired modernity, by means of the schooling rite, or of what that had already be characterized through socialization schoolinhg forme. 

  8. Jardim de Infância de Lisboa: O primeiro jardim de infância em Portugal

    OpenAIRE

    Vilhena, Carla

    1997-01-01

    Neste artigo descreve-se a criação do primeiro jardim de infância em Portugal, O Jardim de Infância de Lisboa, fornecem-se alguns dados acerca do seu funcionamento, dos seus objectivos e currículos. São igualmente referidas algumas críticas feitas a esta escola. In this article we shall describe the setting up of the first nursery school in Portugal and give some details about its running, its aims We shall also outline some of the criticism to which it was subjecte...

  9. Residential electricity consumption in Portugal: Findings from top-down and bottom-up models

    International Nuclear Information System (INIS)

    Wiesmann, Daniel; Lima Azevedo, Ines; Ferrao, Paulo; Fernandez, John E.

    2011-01-01

    An econometric study of the Portuguese residential electricity consumption is presented, with a focus on the influence of dwelling characteristics on consumption. The relationship between the dwelling and household characteristics on per capita residential electricity consumption is estimated at two different scales, involving two distinct databases: the first includes data at the municipality level for 2001, the second is the most recent Portuguese consumer expenditure survey that was collected in 2005 and 2006. The results of the analysis at both scales are consistent and indicate that household and dwelling characteristics have a significant influence on residential electricity consumption. Our results show that in Portugal the direct effect of income on electricity consumption is low and becomes smaller when more relevant control variables are included in the analysis. Future demand of electricity in Portugal will be significantly influenced by trends in socioeconomic factors as well as changes in the building stock. These trends should be taken in consideration in the formulation of policy measures to reduce electricity consumption. - Research highlights: → Econometric study of per capita residential electricity consumption in Portugal. → Comparing models at two levels of aggregation: by municipality and by household. → Using proxies for the dwelling characteristics on the municipality level. → Results from both scales are consistent. → Income elasticity is low and the influence of dwelling characteristics is significant.

  10. Detection of the Invasive Mosquito Species Aedes (Stegomyia) albopictus (Diptera: Culicidae) in Portugal

    Science.gov (United States)

    Osório, Hugo Costa; Zé-Zé, Líbia; Neto, Maria; Silva, Sílvia; Marques, Fátima; Silva, Ana Sofia; Alves, Maria João

    2018-01-01

    The Asian tiger mosquito Aedes albopictus is an invasive mosquito originating from the Asia-Pacific region. This species is of major concern to public and veterinary health because of its vector role in the transmission of several pathogens, such as chikungunya, dengue, and Zika viruses. In Portugal, a National Vector Surveillance Network (REde de VIgilância de VEctores—REVIVE) is responsible for the surveillance of autochthonous, but also invasive, mosquito species at points of entry, such as airports, ports, storage areas, and specific border regions with Spain. At these locations, networks of mosquito traps are set and maintained under surveillance throughout the year. In September 2017, Ae. albopictus was detected for the first time in a tyre company located in the North of Portugal. Molecular typing was performed, and a preliminary phylogenetic analysis indicated a high similarity with sequences of Ae. albopictus collected in Europe. A prompt surveillance response was locally implemented to determine its dispersal and abundance, and adult mosquitoes were screened for the presence of arboviral RNA. A total of 103 specimens, 52 immatures and 51 adults, were collected. No pathogenic viruses were detected. Despite the obtained results suggest low abundance of the population locally introduced, the risk of dispersal and potential establishment of Ae. albopictus in Portugal has raised concern for autochthonous mosquito-borne disease outbreaks. PMID:29690531

  11. Residential electricity consumption in Portugal: Findings from top-down and bottom-up models

    Energy Technology Data Exchange (ETDEWEB)

    Wiesmann, Daniel, E-mail: daniel.wiesmann@ist.utl.p [Instituto Superior Tecnico, Technical University of Lisbon, Avenida Rovisco Pais 1, 1049-001 Lisbon (Portugal); Lima Azevedo, Ines [Department of Engineering and Public Policy, Carnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, PA 15213 (United States); Ferrao, Paulo [Instituto Superior Tecnico, Technical University of Lisbon, Avenida Rovisco Pais 1, 1049-001 Lisbon (Portugal); Fernandez, John E. [Department of Architecture, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139 (United States)

    2011-05-15

    An econometric study of the Portuguese residential electricity consumption is presented, with a focus on the influence of dwelling characteristics on consumption. The relationship between the dwelling and household characteristics on per capita residential electricity consumption is estimated at two different scales, involving two distinct databases: the first includes data at the municipality level for 2001, the second is the most recent Portuguese consumer expenditure survey that was collected in 2005 and 2006. The results of the analysis at both scales are consistent and indicate that household and dwelling characteristics have a significant influence on residential electricity consumption. Our results show that in Portugal the direct effect of income on electricity consumption is low and becomes smaller when more relevant control variables are included in the analysis. Future demand of electricity in Portugal will be significantly influenced by trends in socioeconomic factors as well as changes in the building stock. These trends should be taken in consideration in the formulation of policy measures to reduce electricity consumption. - Research highlights: {yields} Econometric study of per capita residential electricity consumption in Portugal. {yields} Comparing models at two levels of aggregation: by municipality and by household. {yields} Using proxies for the dwelling characteristics on the municipality level. {yields} Results from both scales are consistent. {yields} Income elasticity is low and the influence of dwelling characteristics is significant.

  12. Detection of the Invasive Mosquito Species Aedes (Stegomyia albopictus (Diptera: Culicidae in Portugal

    Directory of Open Access Journals (Sweden)

    Hugo Costa Osório

    2018-04-01

    Full Text Available The Asian tiger mosquito Aedes albopictus is an invasive mosquito originating from the Asia-Pacific region. This species is of major concern to public and veterinary health because of its vector role in the transmission of several pathogens, such as chikungunya, dengue, and Zika viruses. In Portugal, a National Vector Surveillance Network (REde de VIgilância de VEctores—REVIVE is responsible for the surveillance of autochthonous, but also invasive, mosquito species at points of entry, such as airports, ports, storage areas, and specific border regions with Spain. At these locations, networks of mosquito traps are set and maintained under surveillance throughout the year. In September 2017, Ae. albopictus was detected for the first time in a tyre company located in the North of Portugal. Molecular typing was performed, and a preliminary phylogenetic analysis indicated a high similarity with sequences of Ae. albopictus collected in Europe. A prompt surveillance response was locally implemented to determine its dispersal and abundance, and adult mosquitoes were screened for the presence of arboviral RNA. A total of 103 specimens, 52 immatures and 51 adults, were collected. No pathogenic viruses were detected. Despite the obtained results suggest low abundance of the population locally introduced, the risk of dispersal and potential establishment of Ae. albopictus in Portugal has raised concern for autochthonous mosquito-borne disease outbreaks.

  13. Nocturnal Reversed Flows Above Parallel Ridges in Perdigão, Portugal

    Science.gov (United States)

    Krishnamurthy, R.; Fernando, H. J.; Leo, L. S.; Vassallo, D.; Hocut, C. M.; Creegan, E.; Rodriguez, C. V.; Palma, J. L.

    2017-12-01

    Prediction of topographically forced or induced wind events is extremely important for dispersion modeling and wind energy studies in complex terrain. To improve the current understanding of micro-scale processes over complex terrain, a large-scale field experiment was conducted in Perdigão, Portugal from May 1st, 2017 to June 15th, 2017. Measurements over a periodic valley were performed using 52 meteorological met-masts, 30 Doppler Lidars (scanning & vertical profilers), 2 tethered lifting systems and other remote sensing instruments (Sodar-rass, wind profilers & radiometer), and radiosondes were released every 6 hours over the period of study. The observations showed several cases of flow reversals confined to a thin layer of 70 - 100 m above the ridge under stably stratified conditions. These flow reversals were mostly observed during the lee wave formation over the periodic valley. It was observed that the flow reversal occurs predominantly under two atmospheric conditions: a) presence of large recirculation zones on the lee side of the hill causing a pressure gradient between the lee-side floor and the mountain ridge, and b) local change in the horizontal pressure gradient due to differential heating rates of the neighboring valley atmospheres. Microscale flow simulations could capture these observed flow reversals. Based on the network of tower instruments and remote sensing devices, the development, structure and occurrences of the flow reversals are being analyzed and quantified. Since these flow reversals are observed within the rotor swept area of modern wind turbines, they would drastically increase the fatigue loads on wind turbine blades. This presentation will include reversed flow observations from several synchronized scanning Doppler Lidars and meteorological towers and a theoretical framework for reverse flow over parallel valleys.

  14. Notes on Bolboschoenus glaucus, a new species to the flora of Portugal

    Czech Academy of Sciences Publication Activity Database

    Hroudová, Zdenka; Zákravský, Petr; Jarolímová, Vlasta

    2007-01-01

    Roč. 22, 1-4 (2007), s. 211-220 ISSN 0874-9035 R&D Projects: GA AV ČR(CZ) IAA6005905 Institutional research plan: CEZ:AV0Z60050516 Keywords : taxonomy * flora of Portugal * weed s Subject RIV: EF - Botanics

  15. Retrospective and prospective analysis of policy incentives for wind power in Portugal

    Science.gov (United States)

    Pena Cabra, Ivonne A.

    Concerns over climate change impacts, goals to increase environmental sustainability, and questions about the reliability of fuel supply have led several countries to pursue the goal of increasing the share of renewable energy sources in their electricity grid. Portugal is one of the leading countries for wind electricity generation. Wind diffusion in Portugal started in the early 2000's and in 2013 wind electricity generation accounted for more than 24% (REN 2013b). The large share of wind in Portuguese electricity production is a consequence of European Union (E.U.) mandates and national policies, mainly feed-in tariffs. Discussions on the appropriate policy design and level of incentive to promote renewable energy adoption and meet further renewable capacity goals are ongoing in Portugal, namely in what concerns the level and duration of feed-in tariffs that should be provided to independent power producers. This, in turn, raises the question of whether the past feed-in tariff levels were well designed to achieve the goals of a larger penetration of renewables in the Portuguese grid. The policies to induce wind adoption have led to a growth in wind installed capacity and share of electricity generated by wind in Portugal from less than 1% in 2000 to approximately 24% in 2013, but questions arise on their cost-effectiveness and whether alternative policy designs would have led to the same goal. The Portuguese wind feed-in tariffs are a guaranteed incentive which has varied between 85- 180/MWh over the last 20 years (ERSE 2011), and remained approximately constant since 2001 at $101/MWh. They are currently guaranteed for 20 years of production or 44GWh of electricity generation per MW installed (Diario da Republica 2013) - the longest period among countries with high wind electricity share. They do not incorporate any digression rate besides inflation, and are guaranteed for every unit of electricity fed to the grid. There are no power plants that have already

  16. UNIDADES GEOMORFOLÓGICAS DE PORTUGAL CONTINENTAL

    Directory of Open Access Journals (Sweden)

    Diamantino Insua Pereira

    2014-12-01

    Full Text Available São representadas cartograficamente as unidades geomorfológicas identificadas para os 89015 km2 do território de Portugal Continental. A delimitação das unidades teve por base a análise dos padrões da textura fornecida por imagens SRTM, com revisão e adaptação posterior à altimetria e à geologia, para os quais foram usadas bases cartográficas digitais. Foram considerados três níveis taxionómicos que permitem descrever e caracterizar áreas homogéneas do ponto de vista geomorfológico. As três unidades de 1º nível baseiam-se nas unidades morfostruturais clássicas consideradas para a Península Ibérica. As dez unidades de 2º nível constituem, na sua maioria, divisões clássicas do relevo de Portugal Continental, agora agrupadas de acordo com a metodologia adoptada e designadas como unidades morfosculturais. As 56 unidades de 3º nível, ou subunidades morfosculturais, foram individualizadas com base nos padrões de relevo identificados nas imagens SRTM e na observação de campo e adquiriram uma designação baseada essencialmente nas geoformas que as individualizam e na toponímia local. As unidades geomorfológicas identificadas são descritas através de características do relevo, dissecação fluvial, estruturas, tipo de drenagem e base geológica, bem como de parâmetros numéricos gerados de forma automática, como classes de altitude e de declividade. Pretende-se que o mapa elaborado possa contribuir para a gestão territorial, em especial na tomada de decisões em conservação da natureza.

  17. King João II of Portugal “O Principe Perfeito” and the Jews (1481-1495

    Directory of Open Access Journals (Sweden)

    Soyer, François

    2009-06-01

    Full Text Available King João II (1481-1495 is chiefly remembered in Portuguese historiography as the first “modern” King of Portugal and a monarch who vigorously worked to restore the status of the Portuguese Crown, weakened during the reign of his father Afonso V (1438-1481. In Jewish historiography, however, João II has become infamous for his persecution of the Jews who came to Portugal after their expulsion from Castile in 1492 as well as his order to seize Jewish children from their parents so that they could be converted to Christianity and sent to colonize the Island of São Tomé. Using Hebrew, Spanish and Portuguese sources, this article examines in detail the nature of the relations that existed between João II and the Jews, both those who were natives of Portugal as well as the Jewish exiles from Castile.

    El rey João II es recordado en la historiografía portuguesa principalmente como el primer rey «moderno» de Portugal, y un monarca que trabajó enérgicamente para restaurar el estatus de la Corona, debilitada durante el reinado de su padre Afonso V (1438-1481. Sin embargo, la historiografía judía ha construido una imagen del rey como infame por su persecución de los judíos expulsos llegados de Castilla en 1492, así como por la orden de sustracción de niños judíos a sus progenitores para usarlos en la colonización de la isla de São Tomé. Mediante el uso de fuentes hebreas, hispánicas y portuguesas, este artículo examina de forma detallada la naturaleza de las relaciones existentes entre João II y los judíos, tanto de los que eran nativos de Portugal, como de los castellanos exiliados.

  18. Detection of Anaplasma phagocytophilum DNA in Ixodes ticks (Acari: Ixodidae) from Madeira Island and Setubal District, mainland Portugal.

    Science.gov (United States)

    Santos, Ana Sofia; Santos-Silva, Maria Margarida; Almeida, Victor Carlos; Bacellar, Fátima; Dumler, John Stephen

    2004-09-01

    A total of 278 Ixodes ticks, collected from Madeira Island and Setubal District, mainland Portugal, were examined by polymerase chain reaction (PCR) for the presence of Anaplasma phagocytophilum. Six (4%) of 142 Ixodes ricinus nymphs collected in Madeira Island and 1 nymph and 1 male (2%) of 93 I. ventalloi collected in Setubal District tested positive for A. phagocytophilum msp2 genes or rrs. Infection was not detected among 43 I. ricinus on mainland Portugal. All PCR products were confirmed by nucleotide sequencing to be identical or to be most closely related to A. phagocytophilum. To our knowledge, this is the first evidence of A. phagocytophilum in ticks from Setubal District, mainland Portugal, and the first documentation of Anaplasma infection in I. ventalloi. Moreover, these findings confirm the persistence of A. phagocytophilum in Madeira Island's I. ricinus.

  19. Canine babesiosis in northern Portugal and molecular characterization of vector-borne co-infections

    Science.gov (United States)

    2010-01-01

    Background Protozoa and bacteria transmitted by arthropods, including ticks and phlebotomine sand flies, may cause a wide range of canine vector-borne diseases. Dogs can be simultaneously or sequentially infected with multiple pathogens. Canine babesiosis caused by Babesia canis canis and Babesia canis vogeli is known to occur in Portugal. This study assessed, by means of blood smear examination, PCR and DNA nucleotide sequencing, the presence of Babesia spp. and co-infecting agents Leishmania, Anaplasma/Ehrlichia and Hepatozoon in 45 dogs from northern Portugal clinically suspected of babesiosis. Results Forty-four dogs (98%) had infection with B. canis canis and one with B. canis vogeli. Co-infections were detected in nine animals (20%). Eight dogs were found infected with two vector-borne agents: six with B. canis canis and Leishmania infantum; one with B. canis canis and Ehrlichia canis; and one with B. canis canis and Hepatozoon canis. Another dog was infected with three vector-borne pathogens: B. canis vogeli, E. canis and L. infantum. Overall, L. infantum was found in seven (16%), E. canis in two (4%), and H. canis in one (2%) out of the 45 dogs with babesiosis. Almost 90% of the 45 cases of canine babesiosis were diagnosed in the colder months of October (18%), November (27%), December (20%), February (13%) and March (9%). Co-infections were detected in February, March, April, May, October and November. Twenty-two (50%) out of 44 dogs infected with B. canis were found infested by ticks including Dermacentor spp., Ixodes spp. and Rhipicephalus sanguineus. Mortality (9%) included two co-infected dogs that died spontaneously and two with single infections that were euthanized. Conclusions Babesia canis canis is the main etiological agent of canine babesiosis in northern Portugal. A higher sensitivity of Babesia spp. detection was obtained with PCR assays, compared to the observation of blood smears. Twenty percent of the dogs were co-infected with L. infantum

  20. Canine babesiosis in northern Portugal and molecular characterization of vector-borne co-infections

    Directory of Open Access Journals (Sweden)

    Machado João

    2010-04-01

    Full Text Available Abstract Background Protozoa and bacteria transmitted by arthropods, including ticks and phlebotomine sand flies, may cause a wide range of canine vector-borne diseases. Dogs can be simultaneously or sequentially infected with multiple pathogens. Canine babesiosis caused by Babesia canis canis and Babesia canis vogeli is known to occur in Portugal. This study assessed, by means of blood smear examination, PCR and DNA nucleotide sequencing, the presence of Babesia spp. and co-infecting agents Leishmania, Anaplasma/Ehrlichia and Hepatozoon in 45 dogs from northern Portugal clinically suspected of babesiosis. Results Forty-four dogs (98% had infection with B. canis canis and one with B. canis vogeli. Co-infections were detected in nine animals (20%. Eight dogs were found infected with two vector-borne agents: six with B. canis canis and Leishmania infantum; one with B. canis canis and Ehrlichia canis; and one with B. canis canis and Hepatozoon canis. Another dog was infected with three vector-borne pathogens: B. canis vogeli, E. canis and L. infantum. Overall, L. infantum was found in seven (16%, E. canis in two (4%, and H. canis in one (2% out of the 45 dogs with babesiosis. Almost 90% of the 45 cases of canine babesiosis were diagnosed in the colder months of October (18%, November (27%, December (20%, February (13% and March (9%. Co-infections were detected in February, March, April, May, October and November. Twenty-two (50% out of 44 dogs infected with B. canis were found infested by ticks including Dermacentor spp., Ixodes spp. and Rhipicephalus sanguineus. Mortality (9% included two co-infected dogs that died spontaneously and two with single infections that were euthanized. Conclusions Babesia canis canis is the main etiological agent of canine babesiosis in northern Portugal. A higher sensitivity of Babesia spp. detection was obtained with PCR assays, compared to the observation of blood smears. Twenty percent of the dogs were co

  1. Study on Energy Productivity Ratio (EPR) at palm kernel oil processing factory: case study on PT-X at Sumatera Utara Plantation

    Science.gov (United States)

    Haryanto, B.; Bukit, R. Br; Situmeang, E. M.; Christina, E. P.; Pandiangan, F.

    2018-02-01

    The purpose of this study was to determine the performance, productivity and feasibility of the operation of palm kernel processing plant based on Energy Productivity Ratio (EPR). EPR is expressed as the ratio of output to input energy and by-product. Palm Kernel plan is process in palm kernel to become palm kernel oil. The procedure started from collecting data needed as energy input such as: palm kernel prices, energy demand and depreciation of the factory. The energy output and its by-product comprise the whole production price such as: palm kernel oil price and the remaining products such as shells and pulp price. Calculation the equality of energy of palm kernel oil is to analyze the value of Energy Productivity Ratio (EPR) bases on processing capacity per year. The investigation has been done in Kernel Oil Processing Plant PT-X at Sumatera Utara plantation. The value of EPR was 1.54 (EPR > 1), which indicated that the processing of palm kernel into palm kernel oil is feasible to be operated based on the energy productivity.

  2. A new carbon tax in Portugal: A missed opportunity to achieve the triple dividend?

    International Nuclear Information System (INIS)

    Pereira, Alfredo M.; Pereira, Rui M.; Rodrigues, Pedro G.

    2016-01-01

    In 2014, the Portuguese government appointed a Commission for Environmental Tax Reform that formulated a carbon-tax proposal designed to achieve three dividends: to help Portugal meet the European Union's target for emissions reductions by 2030, to boost long-term employment and GDP above their pre-carbon-tax levels, and to strengthen public finances by lowering public indebtedness. A key feature of this proposal was a judicious set of mixed strategies to recycle all carbon-tax revenues back into the economy. In this note, we show how the carbon tax that the Portuguese Parliament eventually approved deviated from such guidelines, and ultimately failed to achieve the triple dividend. We argue that authorities need to quickly amend the existing legislation to avoid this misguided attempt turning into a missed opportunity to improve environmental, macroeconomic, and fiscal outcomes. - Highlights: •In a general-equilibrium model, we simulate the effects of a carbon tax in Portugal. •A carbon tax is needed for Portugal to meet its 2030 target in emissions reductions. •In the long run, it's possible to design a carbon tax to achieve the triple dividend. •The Portuguese parliament ultimately approved an unsatisfactory carbon-tax package. •Carbon-tax revenues must be recycled into lower taxes and promote energy efficiency.

  3. Psicologia feminista em Portugal : dificuldades e conquistas

    OpenAIRE

    Saavedra, Luísa

    2010-01-01

    Pretende-se, com este artigo, fazer um balanço do que tem sido a Psicologia Feminista em Portugal. Tendo em conta que cada ciência comporta evoluções e posições epistemológicas e metodológicas distintas, começar-se-á por traçar em linhas gerais alguns marcos da psicologia no que diz respeito à forma de abordar as questões das mulheres e homens e definindo o que se entende por psicologia feminista. Seguidamente, serão evidenciados alguns aspectos políticos e sociais que condicionaram o desenvo...

  4. Public Management Reform in Napoleonic states: france, greece, Italy, Portugal, Spain

    OpenAIRE

    E. Ongaro

    2008-01-01

    The special issue fills a gap in literature by providing systematic and comparative analysis of public management reform in five under-investigated countries in the Napoleonic administrative tradition: France, Greece, Italy, Portugal, Spain. It thus provides an important contribution to the widening of the comparative research agenda in public management

  5. The Importance of Housing in Portugal in the Age of Austerity

    DEFF Research Database (Denmark)

    Alves, Sonia; Veludo, Ricardo

    2014-01-01

    -specific political factors bearing upon it. By using statistical data and a literature review, this paper will provide an overview of the key factors shaping the housing system in Portugal in recent decades. We demonstrate the critical importance of housing in the Portuguese economy and society in regard to its...

  6. Stratigraphie et structure de Trás-os-Montes oriental (Portugal)

    NARCIS (Netherlands)

    Ribeiro, Antonio; Almeida Rebelo, Jose

    1967-01-01

    Rocks in the eastern part of the province of Trás-os-Montes, N. Portugal belong to five units: 1: a complex of pre-Ordovician schists and greywackes; 2: Ordovician and Silurian sediments; 3: a low-grade metamorphic scries of Silurian age; 4: two complexes of probably Precambrian, predominantly meso-

  7. Una historia de diseño del cartel en Portugal del siglo XVII al XIX

    Directory of Open Access Journals (Sweden)

    María Helena Ferreira Braga Barbosa

    2017-11-01

    Full Text Available To write an history of the design of the poster about three centuries in Portugal allows to understand how this artefact has changed over time. Usually, the result does not configure the reasons that gave rise of the poster, because they are not always visible and so, they don’t illustrate the reality in which they emerged. This article reveals a series of factors associated not only with the historical events, as well the adjacent constraints to design a poster. Portugal has in some cases a particular path with regard to the design history of the poster. To reveal this history the adopted methodology to explain this narrative will refer the technology (paper production and selection, printing techniques, use of different materials, programme (categories of posters – political, cultural and commercial – in parallel with the historical events and authorship (anonymous and identified posters, styles and references. The article is divided in four sections, where each section is related to one century. The set of examples collected contribute to the knowledge of the history of design of the poster in Portugal.

  8. Forest Owners’ Organizations in North and Central Portugal – Assessment of Success

    Directory of Open Access Journals (Sweden)

    Diana Feliciano

    2011-06-01

    Full Text Available Background and Purpose: The emergence of forest owners’ organizations (FOOs in Portugal occurred in the 1990s. Fifteen years later there were 173 FOOs providing services to the private forest owners and also to the whole of society. This study aims to evaluate the success of FOOs in increasing their membership and the quantity of services provided. Material and Methods: Eight FOOs from the North and Central Portugal were chosen as case studies. Quantitative data on membership numbers and number of services provided by the eight case studies were collected from the archives of FORESTIS or directly at the FOOs headquarters. Qualitative data from newsletters, annual reports, local newspapers and letters were also collected to be further analysed. Secondary data collected cover a period of ten years (1994-2005. In addition, eight interviews to members of staff or FOOs directors were conducted in 2005. It was hypothesised that the number of members and the quantity of services provided may be interrelated and that the turnover of staff and their productivity influence the success of FOOs in increasing their membership and providing technical advice services. Results and Conclusion: The study showed that although most FOOs were successful in making their membership grow, there were big differences in the number of members, in the forest area covered by them and in the quantity of services provided. It was concluded that human capital, financial capital and path dependence were the factors that most constrained the success FOOs in North and Central Portugal.

  9. Cancer incidence predictions in the North of Portugal: keeping population-based cancer registration up to date.

    Science.gov (United States)

    Castro, Clara; Antunes, Luís; Lunet, Nuno; Bento, Maria José

    2016-09-01

    Decision making towards cancer prevention and control requires monitoring of trends in cancer incidence and accurate estimation of its burden in different settings. We aimed to estimate the number of incident cases in northern Portugal for 2015 and 2020 (all cancers except nonmelanoma skin and for the 15 most frequent tumours). Cancer cases diagnosed in 1994-2009 were collected by the North Region Cancer Registry of Portugal (RORENO) and corresponding population figures were obtained from Statistics Portugal. JoinPoint regression was used to analyse incidence trends. Population projections until 2020 were derived by RORENO. Predictions were performed using the Poisson regression models proposed by Dyba and Hakulinen. The number of incident cases is expected to increase by 18.7% in 2015 and by 37.6% in 2020, with lower increments among men than among women. For most cancers considered, the number of cases will keep rising up to 2020, although decreasing trends of age-standardized rates are expected for some tumours. Cervix was the only cancer with a decreasing number of incident cases in the entire period. Thyroid and lung cancers were among those with the steepest increases in the number of incident cases expected for 2020, especially among women. In 2020, the top five cancers are expected to account for 82 and 62% of all cases diagnosed in men and women, respectively. This study contributes to a broader understanding of cancer burden in the north of Portugal and provides the basis for keeping population-based incidence estimates up to date.

  10. Toward the antioxidant and chemical characterization of mycorrhizal mushrooms from northeast Portugal.

    Science.gov (United States)

    Reis, Filipa S; Heleno, Sandrina A; Barros, Lillian; Sousa, Maria João; Martins, Anabela; Santos-Buelga, Celestino; Ferreira, Isabel C F R

    2011-08-01

    Mushrooms are widely appreciated all over the world for their nutritional properties and pharmacological value as sources of important bioactive compounds. Mycorrhizal macrofungi associate with plant roots constituting a symbiotic relationship. This symbiosis could influence the production of secondary metabolites, including bioactive compounds. We focused on the evaluation of antioxidant potential and chemical composition of mycorrhizal mushrooms species from Northeast Portugal: Amanita caesarea, Amanita muscaria, Amanita pantherina, Chroogomphus fulmineus, Cortinarius anomalus, Cortinarius collinitus, Cortinarius violaceus, Lactarius quietus, Lactarius volemus, Russula sardonia, Suillus luteus, and Tricholoma ustale. A similar profile of metabolites was observed in the studied species with the order sugars > fat > ascorbic acid > phenolic compounds > tocopherols. Nevertheless, the samples revealed different compositions: prevalence of sugars in L. volemus, fat and ascorbic acid in A. muscaria, phenolic compounds in C. anomalus and tocopherols, and antioxidant activity in S. luteus. Chemical characterization of 12 mycorrhizal mushrooms was achieved. They are sources of nutraceuticals, such as sugars and fatty acids, and contain bioactive compounds, such as vitamins and phenolic acids. Edible species can be incorporated in diets as sources of antioxidants, while nonedible species can be explored as sources of bioactive metabolites. © 2011 Institute of Food Technologists®

  11. A History and Historiography of Foreign Languages Teaching and Learning in Portugal

    Science.gov (United States)

    Santos, Ana Clara

    2018-01-01

    This "state of the art" review on the history of language teaching in Portugal provides an opportunity for a historiographical analysis, highlighting the relationships between languages, the links between languages and educational policy and implementation, and the cultural implications resulting from this. Researching language teaching…

  12. Plano de marketing para a venda de camiões Volvo em Portugal – Auto Sueco, Lda.

    OpenAIRE

    Martins, José Nuno da Rocha

    2014-01-01

    O principal objetivo deste estudo foi o desenvolvimento de um plano de marketing para a venda de camiões Volvo em Portugal. O estudo pretende dotar a Auto Sueco Lda. de ferramentas que lhe permitam melhorar a performance no negócio da venda de camiões Volvo em Portugal. Nesse sentido, o plano começa por fazer uma caracterização detalhada da envolvente externa, bem como elaborar um diagnóstico da situação interna da empresa. Mediante esta análise, são enumerados os pontos que a empresa deve...

  13. Destination Brand Personality of Portugal for the Russian-Speaking Market

    Directory of Open Access Journals (Sweden)

    Taisiya Chaykina

    2014-03-01

    Full Text Available Nowadays brand personality is admitted to be one of the essential parts of brand strategy. It has also become a popular aspect of destination branding due to the fact that destinations are constantly competing for visitors attention in various ways. The term of branding has been first applied to marketing of services or places since the 1990’s. Later on it was broadened and utilized by specialists in the field of tourism marketing. Tourism brand personality is a relatively new one and there are only few works devoted to brand personality of countries as tourism destinations. Keeping in mind the novelty of the research area, this study was planned as exploratory in nature. The stated goal of the research is: to identify the brand personality attributes ascribed to Portugal by the Russian-speaking market and compare the possible existing differences of attributes among the subgroups of the study (actual visitors and possible future visitors. The results of this research might be interesting to the local officials and to business representatives as it highlights the main attributes of Portugal brand personality from the Russian speaking people’s point of view.

  14. Precipitation Thresholds for Triggering Floods in the Corgo Basin, Portugal

    Directory of Open Access Journals (Sweden)

    Mónica Santos

    2016-08-01

    Full Text Available Thresholds based on critical combinations of amount/duration of precipitation and flood events were estimated for the Corgo hydrographic basin, in northern Portugal. Thirty-one flood events in the Corgo basin were identified between 1865 and 2011 from a database of hydrometeorological disasters in Portugal. The minimum, maximum, and pre-warning thresholds that define the boundaries for flood occurrence were determined. The results show that the ratio between the total number of floods and precipitation events exceeding the minimum threshold denotes a relatively low probability of successful forecasting. This result may be due to the reduced number of flooding events in the floods database, which only include floods that caused damage as reported by the media. The estimated maximum threshold is not adequate for use in floods, since the majority of true positives are below this limit. However, and more interestingly, the retrospective verification of the estimated thresholds suggests that the minimum and pre-warning thresholds are well adjusted. Therefore, the application of these precipitation thresholds may contribute to minimize possible situations of pre-crisis or immediate crisis by reducing the flood consequences and the resources involved in emergency response to flood events.

  15. Labour Human Rights in Portugal: Challenges to Their Effectiveness

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    Marina Pessoa Henriques

    2016-09-01

    Full Text Available This article discusses the relationship between Portugal and the International Labour Organization (ILO, considering the extent to which the ILO’s system of international labour standards is recognised at the national level in the context of labour law and labour relations, and observes the ILO’s special procedures (complaints and representations in the field of international labour human rights. The use of the ILO’s system of complaints and representations by national social actors is relevant for the configuration of the Portuguese labour relations system, considering that the changes and tensions emerging from labour relations gain expression and voice within these mechanisms. In order to assess the effectiveness of national laws and regulations, we analyse the effects of ILO’s special control mechanisms on the state, law and labour relations system. Indeed, the use of the ILO’s complaints and representations system seems to reveal the ineffectiveness of labour human rights in Portugal. The ILO’s special procedures are analysed according to three functions: a political function as a result of the mediation state/labour civil society; an instrumental/procedural function referring to the regulation of conflicts; and a symbolic function related to the setting/expression of social expectations. The soft law characteristics associated with this mechanism as well as its results are also considered. En este artículo se analiza la relación entre Portugal y la Organización Internacional del Trabajo (OIT, teniendo en cuenta el grado en que el sistema de normas laborales internacionales de la OIT es reconocido a nivel nacional en el contexto del derecho laboral y las relaciones laborales, y observa los procedimientos especiales (quejas y reclamaciones de la OIT en el ámbito de los derechos humanos laborales internacionales. Para la configuración del sistema de relaciones laborales portugués, es relevante el uso que actores sociales

  16. Training requirements for agro-food industry in Portugal

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    Pedro D. Gaspar

    2015-04-01

    Full Text Available Agro-food companies are aware that the technical and soft skills of their employees directly influence business performance and, consequently, improving those skills will enhance the effectiveness and efficiency of their companies. This paper presents the main results of the AgriTraining project “Training requirements for the agro-food industry". Activities in pursuit of the objectives of this project involved: (1 analysis of the training needs in the agro-food industry in Portugal; (2 analysis of the training provision and the training organizations; (3 analysis of market trends; (4 definition of a training strategy; and (5 adjustment and development of training strategies for the agro-food sector. This last activity comprised the development of training curricula, suitable for the food sector as a whole and adjusted for the specific needs of some traditional industries, in order to promote the development and competitiveness of the agro-food industry in Portugal. Such training curricula aimed to promote the uptake of innovative technologies and methodologies, increase the ability of agro-food industries to invest and take risks, and enable adoption of European Community standards for production and marketing. Gaps in training supply were identified and the training provision was updated according to the needs of the agro-food companies. It was determined that companies need and demand knowledge and innovation to increase their competitive position for internationalization purposes. It was possible to define a training strategy based on market-orientation for agro-food differentiation.

  17. Estratégias para aumentar a sensibilidade da farmacovigilância em Portugal Estrategias para aumentar la sensibilidad de la farmacovigilancia en Portugal Strategies to increase the sensitivity of pharmacovigilance in Portugal

    Directory of Open Access Journals (Sweden)

    Inês Ribeiro-Vaz

    2011-02-01

    Full Text Available OBJETIVO: Avaliar os resultados de intervenção para melhoria da quantidade e relevância das notificações de reacções adversas a medicamentos. MÉTODOS: Foi implementado um estudo controlado aleatorizado, por agrupamentos em farmacêuticos a exercer actividade profissional na região norte de Portugal, em 2007. Após aleatorização, 364 indivíduos foram alocados ao grupo de intervenção (261 na intervenção telefónica e 103 nos workshops; o grupo de controlo foi constituído por 1.103 farmacêuticos. Na intervenção educativa foram abordados a problemática das reacções adversas a medicamentos, o impacto na saúde pública e a notificação espontânea. Quanto à relevância, as reações adversas foram classificadas em graves e inesperadas. A análise estatística foi efectuada com base no princípio intention-to-treat; aplicaram-se modelos lineares generalizados mistos, utilizando o método penalized quasi-likelihood. Os farmacêuticos estudados foram seguidos durante um período de 20 meses. RESULTADOS: A intervenção aumentou três vezes a taxa de notificação espontânea das reações adversas (RR = 3,22; IC 95%: 1,33; 7,80 relativamente ao grupo de controlo. Houve incremento da relevância das notificações com aumento das reações adversas graves em cerca de quatro vezes (RR = 3,87; IC 95%: 1,29;11,61 e inesperadas em cinco vezes (RR = 5,02; IC 95%: 1,33;18,93, relativamente ao grupo de controlo. CONCLUSÕES: As intervenções educativas aumentam significativamente, por até quatro meses, a quantidade e a relevância das notificações espontâneas de reacções adversas a medicamentos por parte dos farmacêuticos da região norte de Portugal.OBJETIVO: Evaluar los resultados de intervención para mejoría de la cantidad y relevancia de las notificaciones de reacciones adversas a medicamentos. MÉTODOS: Fue implementado un estudio controlado aleatorio, por agrupaciones de farmacéuticos que ejercen actividad profesional

  18. Nocturnal surface ozone enhancement over Portugal during winter: Influence of different atmospheric conditions

    KAUST Repository

    Kulkarni, Pavan S.

    2016-09-24

    Four distinct nocturnal surface ozone (NSO) enhancement events were observed, with NSO concentration exceeding 80μg/m3, at multiple ozone (O3) monitoring stations (32 sites) in January, November and December between year 2000–2010, in Portugal. The reasonable explanation for the observed bimodal pattern of surface ozone with enhanced NSO concentration during nighttime has to be transport processes, as the surface ozone production ceases at nighttime. Simultaneous measurements of O3 at multiple stations during the study period in Portugal suggest that horizontal advection alone cannot explain the observed NSO enhancement. Thus, detailed analysis of the atmospheric conditions, simulated with the Weather Research and Forecasting (WRF) model, were performed to evaluate the atmospheric mechanisms responsible for NSO enhancement in the region. Simulations revealed that each event occurred as a result of one or the combination of different atmospheric processes such as, passage of a cold front followed by a subsidence zone; passage of a moving surface trough, with associated strong horizontal wind speed and vertical shear; combination of vertical and horizontal transport at the synoptic scale; formation of a low level jet with associated vertical mixing below the jet stream. The study confirmed that large-scale flow pattern resulting in enhanced vertical mixing in the nocturnal boundary layer, plays a key role in the NSO enhancement events, which frequently occur over Portugal during winter months. © 2016 Elsevier Ltd

  19. Nocturnal surface ozone enhancement over Portugal during winter: Influence of different atmospheric conditions

    KAUST Repository

    Kulkarni, Pavan S.; Dasari, Hari Prasad; Sharma, Ashish; Bortoli, D.; Salgado, Rui; Silva, A.M.

    2016-01-01

    Four distinct nocturnal surface ozone (NSO) enhancement events were observed, with NSO concentration exceeding 80μg/m3, at multiple ozone (O3) monitoring stations (32 sites) in January, November and December between year 2000–2010, in Portugal. The reasonable explanation for the observed bimodal pattern of surface ozone with enhanced NSO concentration during nighttime has to be transport processes, as the surface ozone production ceases at nighttime. Simultaneous measurements of O3 at multiple stations during the study period in Portugal suggest that horizontal advection alone cannot explain the observed NSO enhancement. Thus, detailed analysis of the atmospheric conditions, simulated with the Weather Research and Forecasting (WRF) model, were performed to evaluate the atmospheric mechanisms responsible for NSO enhancement in the region. Simulations revealed that each event occurred as a result of one or the combination of different atmospheric processes such as, passage of a cold front followed by a subsidence zone; passage of a moving surface trough, with associated strong horizontal wind speed and vertical shear; combination of vertical and horizontal transport at the synoptic scale; formation of a low level jet with associated vertical mixing below the jet stream. The study confirmed that large-scale flow pattern resulting in enhanced vertical mixing in the nocturnal boundary layer, plays a key role in the NSO enhancement events, which frequently occur over Portugal during winter months. © 2016 Elsevier Ltd

  20. Zola, Lourdes and the New Religious Crowd in Ideological Debates in Portugal (1894-1932 Zola, Lourdes et la foule religieuse dans les débats idéologiques au Portugal (1894-1932

    Directory of Open Access Journals (Sweden)

    Eduardo Cintra Torres

    2010-09-01

    Full Text Available The impact of Émile Zola’s novel on Lourdes was felt in Portugal even before its publication in France in 1894. The naturalist writer’s documentary fiction plucked a central chord in the political and religious debate of the time, particularly the dichotomy between science and religion, the renewal of faith and the legitimacy of the crowd in public spaces. This paper deals with only one aspect of that debate, active in Portugal between 1894 and 1932 – the impact of Zola´s innovative thesis about Lourdes’ new religious crowd and ‘the crowd’s healing power’. The development of the debates shows how Catholic sectors increasingly incorporated the ‘crowd’ into renewed Catholicism, especially after the Fátima events of 1917, while the liberal bourgeoisie continued to reject the masses.L’impact du roman Lourdes d’Émile Zola au Portugal s’est fait avant même sa publication en France en 1894. Cette fiction documentaire de l’écrivain naturaliste a touché une corde sensible dans les débats politiques et religieux de l’époque, notamment en atour de questions telles que la dichotomie entre science et religion, le renouveau de la foi catholique et la légitimité de la foule dans l’espace public. Cet article se penche sur un aspect particulier des débats qui furent actifs au Portugal entre 1894 et 1932 : l’impact de la thèse originale de Zola sur les foules religieuses de Lourdes et le pouvoir guérisseur de la foule. Le développement des débats montre comment les catholiques ont progressivement incorporé la « foule » dans leur vision d’un catholicisme renouvelé, alors que la bourgeoisie libérale continua à rejeter les masses, particulièrement après les apparitions de Fátima en 1917.

  1. For the improvement of Heart Failure treatment in Portugal - Consensus statement.

    Science.gov (United States)

    Fonseca, Cândida; Brito, Dulce; Cernadas, Rui; Ferreira, Jorge; Franco, Fátima; Rodrigues, Teresa; Morais, João; Silva Cardoso, José

    2017-01-01

    Heart failure is a syndrome with high prevalence, morbidity and mortality, but awareness of the disease is poor among the general public and policy makers. This document, which was prepared by a group of experts consisting of cardiologists, internists and general practitioners, aims to set out in detail the problem of heart failure in Portugal at several levels: burden of the disease, diagnosis, treatment and monitoring. To this aim, different aspects of the management of the various stages of the disease are identified and discussed in detail, covering both outpatients and hospitalized patients. In order to optimize the medical care provided to these patients, various short-, medium- and long-term solutions and strategies are put forward that have the potential to improve the integration and use of available resources. The intention is to highlight strategies that are not based on a single model but can be adapted to different regional circumstances, in order to increase awareness and improve management of heart failure in Portugal. Copyright © 2016 Sociedade Portuguesa de Cardiologia. Publicado por Elsevier España, S.L.U. All rights reserved.

  2. Detection of Anaplasma phagocytophilum DNA in Ixodes Ticks (Acari: Ixodidae) from Madeira Island and Setúbal District, Mainland Portugal

    Science.gov (United States)

    Santos-Silva, Maria Margarida; Almeida, Victor Carlos; Bacellar, Fátima; Dumler, John Stephen

    2004-01-01

    A total of 278 Ixodes ticks, collected from Madeira Island and Setúbal District, mainland Portugal, were examined by polymerase chain reaction (PCR) for the presence of Anaplasma phagocytophilum. Six (4%) of 142 Ixodes ricinus nymphs collected in Madeira Island and 1 nymph and 1 male (2%) of 93 I. ventalloi collected in Setúbal District tested positive for A. phagocytophilum msp2 genes or rrs. Infection was not detected among 43 I. ricinus on mainland Portugal. All PCR products were confirmed by nucleotide sequencing to be identical or to be most closely related to A. phagocytophilum. To our knowledge, this is the first evidence of A. phagocytophilum in ticks from Setúbal District, mainland Portugal, and the first documentation of Anaplasma infection in I. ventalloi. Moreover, these findings confirm the persistence of A. phagocytophilum in Madeira Island's I. ricinus. PMID:15498168

  3. Mathematics Diagnostic Testing in Engineering: An International Comparison between Ireland and Portugal

    Science.gov (United States)

    Carr, M.; Fidalgo, C.; Bigotte de Almeida, M. E.; Branco, J. R.; Santos, V.; Murphy, E.; Ní Fhloinn, E.

    2015-01-01

    Concern has been expressed throughout Europe about the significant deficiencies in the basic mathematical skills of many engineering undergraduates. Mathematics diagnostic tests in the UK, Ireland and Portugal have shown these shortcomings, which provide a challenge to those striving to introduce more innovative educational practices into…

  4. Ciganos e políticas sociais em Portugal

    Directory of Open Access Journals (Sweden)

    Olga Magano

    2014-01-01

    Full Text Available Considering the social and political changes that took place in Portugal, from April 25, 1974, specifically provided since the democratic system was implemented, became effective an understanding that advocates universal citizenship for all Portuguese. However, not all citizens are in equal circumstances on full access to the rights of citizenship. The objective of this paper is to reflect and discuss some of the impacts of measures and social policies on Gypsies people and families, as well as the (invisible changes, although the underlying behind the plural processes of social and identity reconfiguration.

  5. Legislation for higher education disabled students in Brazil and Portugal: some reflections

    Directory of Open Access Journals (Sweden)

    Francisco Ricardo Lins Vieira de Melo

    2016-08-01

    Full Text Available This study aims to make a critical analysis of legislation regulating the inclusion of disabled students in higher education in Brazil and Portugal. Based on a documentary study, conducted between September and November 2015, the legal standards in recent decades have been analyzed. The results point out different stages of construction of the inclusion policy in the researched countries. It is emphasized that there is a significant variety of norms in the Brazilian context to ensure that these students have equal opportunities, and a scarcity of regulations in Portugal. The legislation has been referred to as an important factor for the development of inclusive education; however it is noteworthy that the existence of legislation does not necessarily imply it is actually complied. Besides legislation, removing barriers for the full participation and learning of disabled students involves awareness, investment in resources, public policy makers and managers’ scientific knowledge to ensure a quality education throughout life for all people.

  6. Particulate Matter and Health Risk under a Changing Climate: Assessment for Portugal

    Directory of Open Access Journals (Sweden)

    Daniela Dias

    2012-01-01

    Full Text Available The potential impacts of climate-induced changes in air pollution levels and its impacts on population health were investigated. The IPCC scenario (SRES A2 was used to analyse the effects of climate on future PM10 concentrations over Portugal and their impact on short-term population exposure and mortality. The air quality modelling system has been applied with high spatial resolution looking on climate changes at regional scale. To quantify health impacts related to air pollution changes, the WHO methodology for health impact assessment was implemented. The results point to 8% increase of premature mortality attributed to future PM10 levels in Portugal. The pollution episodes with daily average PM10 concentration above the current legislated value (50 μg·m−3 would be responsible for 81% of attributable cases. The absolute number of deaths attributable to PM10 under future climate emphasizes the importance of indirect effects of climate change on human health.

  7. O perfil esperado de um professor de contabilidade: uma análise a partir dos estudantes da cidade de Barcelos – Portugal = The expected profile of an accounting professor: an analysis from the students from the city of Barcelos - Portugal

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    Jacqueline Elene de Faria Tolentino

    2014-08-01

    Full Text Available Na Europa a Declaração de Bolonha possibilitou a integração entre os 30 Estados-Membros, facilitando o ingresso no ensino superior e também ampliando as oportunidades de intercâmbio entre as universidades. O objetivo deste trabalho é identificar a percepção dos alunos portugueses quanto à competência necessária ao julgamento de um bom professor. Justifica-se o estudo face à necessidade constante de formar melhores Contadores e logo, também, melhores professores da área Contábil. Para a concretização deste trabalho, foi aplicado um questionário a 127 alunos de uma instituição de ensino localizada na Cidade de Barcelos, no distrito de Braga. O questionário buscou mensurar a importância de cinco competências, atribuídas pelos alunos aos docentes, combinados de maneira a formar doze perfis distintos. Foi concluído que a competência docente e experiência de mercado são os atributos de melhor e pior avaliação. Já, quanto ao perfil, um “bom professor”, no julgamento dos respondentes, é aquele docente que possui uma boa didática, um próximo relacionamento com os alunos, muita experiência de mercado, pouca exigência e amplo conhecimento teórico. In Europe, the Bologna Declaration has enabled the integration among the 30 Member States, facilitating the access to higher education and also expanding opportunities for exchanges among universities. The objective of this work is to identify the perception of Portuguese students concerning the necessary competence for the judgment of a good teacher. The study is justified due to the constant need to form better Accountants, and consequently, also better teachers in the Accounting area. To accomplish this work, a questionnaire was applied to 127 students in an educational institution located in the city of Barcelos, in the district of Braga, Portugal. The questionnaire sought to measure the importance of five teaching skills, assigned by students to teachers, combined to

  8. Consumption Patterns of Energy Drinks in Portuguese Adolescents from A City in Northern Portugal

    Directory of Open Access Journals (Sweden)

    Albino Martins

    2018-04-01

    Conclusion: This study showed a high prevalence of energy drinks consumption among adolescents from a city in Northern Portugal, with self-reported symptoms after consumption and common concomitant use of alcohol.

  9. The Afrotropical Miomantis caffra Saussure 1871 and M. paykullii Stal 1871: first records of alien mantid species in Portugal and Europe, with an updated checklist of Mantodea in Portugal (Insecta: Mantodea

    Directory of Open Access Journals (Sweden)

    Eduardo Marabuto

    2014-11-01

    In the absence of recent revisionary work on the Mantodea of Portugal and given the need to provide an accessible identification tool, both a checklist and a key to species are provided for all species in the country.

  10. LANGUAGE SCHOOLS AND FOREIGN LANGUAGE STUDYING PROGRAMS IN PORTUGAL

    OpenAIRE

    Hritchenko, Iryna

    2017-01-01

    The article is devoted to the description and characterizing of language schools and foreign language studying programs in Portugal. The relevance of language learning for professional, mobility, self-developing means is shown. The main courses and programs are observed and the advantages and disadvantages of each of them are given. It is stated that Portuguese courses mostly follow the Common European Framework of Reference for Languages. A small synopsis of the abilities for each level is p...

  11. Participation in lifelong learning in Portugal and the UK

    OpenAIRE

    Hilary Ingham; Mike Ingham; Jose Adelino Afonso

    2013-01-01

    Lifelong learning (LLL) has now been on the agenda of the European Union and other major international organizations for some considerable time, with the European institutions stressing the need that such learning should be available to all, especially hard to reach groups. This paper seeks to explore LLL participation in Portugal and the UK, two countries at opposite ends of the adult learning spectrum and having very different labour market and educational contexts. Using Labour Force Surve...

  12. Spatio-temporal evolution of forest fires in Portugal

    Science.gov (United States)

    Tonini, Marj; Pereira, Mário G.; Parente, Joana

    2017-04-01

    A key issue in fire management is the ability to explore and try to predict where and when fires are more likely to occur. This information can be useful to understand the triggering factors of ignitions and for planning strategies to reduce forest fires, to manage the sources of ignition and to identify areas and frame period at risk. Therefore, producing maps displaying forest fires location and their occurrence in time can be of great help for accurately forecasting these hazardous events. In a fire prone country as Portugal, where thousands of events occurs each year, it is involved to drive information about fires over densities and recurrences just by looking at the original arrangement of the mapped ignition points or burnt areas. In this respect, statistical methods originally developed for spatio-temporal stochastic point processes can be employed to find a structure within these large datasets. In the present study, the authors propose an approach to analyze and visualize the evolution in space and in time of forest fires occurred in Portugal during a long frame period (1990 - 2013). Data came from the Portuguese mapped burnt areas official geodatabase (by the Institute for the Conservation of Nature and Forests), which is the result of interpreted satellite measurements. The following statistical analyses were performed: the geographically-weighted summary statistics, to analyze the local variability of the average burned area; the space-time Kernel density, to elaborate smoothed density surfaces representing over densities of fires classed by size and on North vs South region. Finally, we emploied the volume rendering thecnique to visualize the spatio-temporal evolution of these events into a unique map: this representation allows visually inspecting areas and time-step more affected from a high aggregation of forest fires. It results that during the whole investigated period over densities are mainly located in the northern regions, while in the

  13. Southern-European Signposts for Critical Popular Adult Education: Italy, Portugal and Spain

    Science.gov (United States)

    Guimaraes, Paula; Lucio-Villegas, Emilio; Mayo, Peter

    2018-01-01

    This paper focuses on three Southern European countries, Italy, Portugal and Spain, to explore examples of projects that provide signposts for a critical popular education that contributes to an ongoing democratic process--one whereby citizens are developed as social actors and members of a collectivity rather than simply passive…

  14. Construction and Modification of the Autonomy of School Mathematical Knowledge in Portugal

    Science.gov (United States)

    Matos, José Manuel

    2016-01-01

    During the second half of the nineteenth century and early twentieth century the discipline of secondary mathematics was gradually built in Portugal and certified teachers, textbooks, programs, special teaching techniques emerge. This consolidation process ends with the emergency of school subjects that develop some kind of autonomy as Chervel…

  15. Astronomy Week in Madeira, Portugal

    Science.gov (United States)

    Augusto, P.; Sobrinho, J. L.

    2012-05-01

    The outreach programme Semanas da Astronomia (Astronomy Weeks) is held in late spring or summer on the island of Madeira, Portugal. This programme has been attracting enough interest to be mentioned in the regional press/TV/radio every year and is now, without doubt, the astronomical highlight of the year on Madeira. We believe that this programme is a good case study for showing how to attract the general public to astronomy in a small (population 250 000, area 900 km2) and fairly isolated place such as Madeira. Our Astronomy Weeks have been different each year and have so far included exhibitions, courses, talks, a forum, documentaries, observing sessions (some with blackouts), music and an astro party. These efforts may contribute towards putting Madeira on the map with respect to observational astronomy, and have also contributed to the planned installation of two observatories in the island.

  16. Experiences and plans of portugal in developing energy markets

    International Nuclear Information System (INIS)

    Duic, N.; Carvalho, M. da G. S.

    2000-01-01

    portuguese government energy strategy concentrates on market opening, correction of distorted prices and gradual increase in competition as laid down by the European Union Directives. The national electricity system is divided into two segments, the public and the independent electric systems. Independent power producers are for the time being mainly producers in special regime (co-generation and renewables) and some hydropower plants, making 15% of the installed capacity. The IPP sell the generated electricity to the public system. The transmission is separated into special legal entity, and grid is open to all competitors. Since the beginning of 1999 all consumers that buy more than 9 GWh of electricity annually, so-called eligible customers, are free to chose their electricity provider. In the process of the local electric system restructuring the government decided to privatise 49,5% of the monopolist, EdP, floating most of 30% immediately on the local and international stock exchanges in the biggest Portuguese privatisation event so far, and selling the rest to institutional investors. Later, further 19,5% were similarly privatised. The introduction of natural gas in Portugal started in 1997 by giving local distribution concession and making big consumers eligible to buy directly from the monopolist importer and pipeline owner (GdP). The paper will show the results expected from gradual demonopolisation and privatisation of electric and gas systems in Portugal. (author)

  17. Artisanal salt production in Aveiro/Portugal - an ecofriendly process.

    Science.gov (United States)

    Rodrigues, Carolina M; Bio, Ana; Amat, Francisco; Vieira, Natividade

    2011-11-04

    Solar salinas are man-made systems exploited for the extraction of salt, by solar and wind evaporation of seawater. Salt production achieved by traditional methods is associated with landscapes and environmental and patrimonial values generated throughout history. Since the mid-twentieth century, this activity has been facing a marked decline in Portugal, with most salinas either abandoned or subjected to destruction, making it necessary to find a strategy to reverse this trend.It is, however, possible to generate revenue from salinas at several levels, not merely in terms of good quality salt production, but also by obtaining other products that can be commercialized, or by exploring their potential for tourism, and as research facilities, among others. Furthermore, with an adequate management, biodiversity can be restored to abandoned salinas, which constitute important feeding and breeding grounds for resident and migratory aquatic birds, many of which are protected by European Community Directives.The aims of this manuscript are to present a brief overview on the current state of sea salt exploitation in Portugal and to stress the importance of recovering these salinas for the conservation of this particular environment, for the regional economy, the scientific community and the general public. The Aveiro salina complex is presented in detail, to exemplify salina structure and functioning, as well as current problems and potential solutions for artisanal salinas.

  18. A direita radical em Portugal: da Revolução dos Cravos à era da internet

    OpenAIRE

    Almeida, Fábio Chang de

    2015-01-01

    O presente artigo busca revisitar o desenvolvimento da direita radical em Portugal, desde a queda do regime autoritário (1974) até a era da internet, com ênfase no período entre os anos de 1984 e 2012. A análise abordou dois eixos fundamentais: a criação de organizações culturais e políticas de direita radical e a organização de grupos violentos de conotação racista e xenofóbica. This paper analyzes the development of the radical right in Portugal, since the fall of the authoritarian regim...

  19. NUVEM - New methods to Use gnss water Vapor Estimates for Meteorology of Portugal

    Science.gov (United States)

    Fernandes, R. M. S.; Viterbo, P.; Bos, M. S.; Martins, J. P.; Sá, A. G.; Valentim, H.; Jones, J.

    2014-12-01

    NUVEM (New methods to Use gnss water Vapor Estimates for Meteorology of Portugal) is a collaborative project funded by the Portuguese National Science Foundation (FCT) aiming to implement a multi-disciplinary approach in order to operationalize the inclusion of GNSS-PWV estimates for nowcasting in Portugal, namely for the preparation of warnings of severe weather. To achieve such goal, the NUVEM project is divided in two major components: a) Development and implementation of methods to compute accurate estimates of PWV (Precipitable Water Vapor) in NRT (Near Real-Time); b) Integration of such estimates in nowcasting procedures in use at IPMA (Portuguese Meteorological Service). Methodologies will be optimized at SEGAL to passive and actively access to the data; the PWV estimations will be computed using PPP (Precise Point Positioning), which permits the estimation of each individual station separately; solutions will be validated using internal and external values; and computed solutions will be transferred timely to the IPMA Operational Center. Validation of derived estimations using robust statistics is an important component of the project. The need for sending computed values as soon as possible to IPMA requires fast but reliable internal (e.g., noise estimation) and external (e.g., feedback from IPMA using other sensors like radiosondes) assessment of the quality of the PWV estimates. At IPMA, the goal is to implement the operational use of GNSS-PWV to assist weather nowcasting in Portugal. This will be done with the assistance of the Meteo group of IDL. Maps of GNSS-PWV will be automatically created and compared with solutions provided by other operational systems in order to help IPMA to detect suspicious patterns at near real time. This will be the first step towards the assimilation of GNSS-PWV estimates at IPMA nowcasting models. The NUVEM (EXPL/GEO-MET/0413/2013) project will also contribute to the active participation of Portugal at the COST Action ES

  20. Phytochemical characterization of wild edible Boletus sp. from Northeast Portugal

    OpenAIRE

    Heleno, Sandrina A.; Barros, Lillian; Martins, Anabela; Sousa, Maria João; Ferreira, Isabel C.F.R.

    2010-01-01

    Our research has been focused on the documentation of nutritional composition and nutraceutical potential of wild mushrooms, making the information available for a better management and conservation of these species and related habitats. In the present work, the chemical composition and bioactivity of three wild edible Boletus sp. (Boletus aereus, Boletus edulis, Boletus reticulatus) from Northeast Portugal were evaluated, in order to valorise these species as sources of important...

  1. Driver mutations (JAK2V617F, MPLW515L/K or CALR), pentraxin-3 and C-reactive protein in essential thrombocythemia and polycythemia vera.

    Science.gov (United States)

    Lussana, Federico; Carobbio, Alessandra; Salmoiraghi, Silvia; Guglielmelli, Paola; Vannucchi, Alessandro Maria; Bottazzi, Barbara; Leone, Roberto; Mantovani, Alberto; Barbui, Tiziano; Rambaldi, Alessandro

    2017-02-22

    The driver mutations JAK2V617F, MPLW515L/K and CALR influence disease phenotype of myeloproliferative neoplasms (MPNs) and might sustain a condition of chronic inflammation. Pentraxin 3 (PTX3) and high-sensitivity C-reactive protein (hs-CRP) are inflammatory biomarkers potentially useful for refining prognostic classification of MPNs. We evaluated 305 with essential thrombocythemia (ET) and 172 polycythemia vera (PV) patients diagnosed according to the 2016 WHO criteria and with full molecular characterization for driver mutations. PTX3 levels were significantly increased in carriers of homozygous JAK2V617F mutation compared to all the other genotypes and triple negative ET patients, while hs-CRP levels were independent of the mutational profile. The risk of haematological evolution and death from any cause was about 2- and 1.5-fold increased in individuals with high PTX-3 levels, while the thrombosis rate tended to be lower. High hs-CRP levels were associated with risk of haematological evolution, death and also major thrombosis. After sequential adjustment for potential confounders (age, gender, diagnosis and treatments) and the presence of JAK2V617F homozygous status, high hs-CRP levels remained significant for all outcomes, while JAK2V617F homozygous status as well as treatments were the factors independently accounting for adverse outcomes among patients with high PTX3 levels. These results provide evidence that JAK2V617F mutation influences MPN-associated inflammation with a strong correlation between allele burden and PTX3 levels. Plasma levels of hs-CRP and PTX3 might be of prognostic value for patients with ET and PV, but their validation in future prospective studies is needed.

  2. Differing trends in the association between obesity and self-reported health in Portugal and Switzerland. Data from national health surveys 1992-2007.

    Science.gov (United States)

    Marques-Vidal, Pedro; Ravasco, Paula; Paccaud, Fred

    2012-08-01

    The escalating prevalence of obesity might prompt obese subjects to consider themselves as normal, as this condition is gradually becoming as frequent as normal weight. In this study, we aimed to assess the trends in the associations between obesity and self-rated health in two countries. Data from the Portuguese (years 1995-6, 1998-6 and 2005-6) and Swiss (1992-3, 1997, 2002 and 2007) National Health Surveys were used, corresponding to more than 130,000 adults (64,793 for Portugal and 65,829 for Switzerland). Body mass index and self-rated health were derived from self-reported data. Obesity levels were higher in Portugal (17.5% in 2005-6 vs. 8.9% in 2007 in Switzerland, p Switzerland (21.8% in 2005-6 vs 3.9% in 2007, p Switzerland, the prevalence of "bad" or "very bad" rates among obese participants, increased from 6.5% in 1992-3 to 9.8% in 2007, while in Portugal it decreased from 41.3% to 32.3%. After multivariate adjustment, the odds ratio (OR) of stating one self's health as "bad" or "very bad" among obese relative to normal weight participants, almost doubled in Switzerland: from 1.38 (95% confidence interval, CI: 1.01-1.87) in 1992-3 to 2.64 (95% CI: 2.14-3.26) in 2007, and similar findings were obtained after sample weighting. Conversely, no such trend was found in Portugal: 1.35 (95% CI: 1.23-1.48) in 1995-6 and 1.52 (95% CI: 1.37-1.70) in 2005-6. Obesity is increasing in Switzerland and Portugal. Obesity is increasingly associated with poorer self-health ratings in Switzerland but not in Portugal.

  3. High-pressure synthesis and structural, physical properties of CaIr1-xPtxO3 and CaIr1-xRhxO3

    Science.gov (United States)

    Hirai, S.; Bromiley, G. D.; Klemme, S.; Irifune, T.; Ohfuji, H.; Attfield, P.; Nishiyama, N.

    2010-12-01

    in terms of materials science applications. To our knowledge, this will be the first report on structural, magnetic and charge-transport properties of B-site substituted solid solutions of post-perovskite oxides with 4d/5d transition metals. High-quality polycrystalline samples of CaIr1-xPtxO3 and CaIr1-xRhxO3 have been obtained at high pressures, and structural, magnetic and charge-transport properties of the compounds will be reported. ODF analysis reveals that solutions of CaIrO3, CaPtO3 and CaRhO3 exhibit similar grain growth features to the mother compound, although growth in [0 1 0] plays a more dominant role than the growth in [0 0 1] for the solid solutions. CaIrO3 is a characteristic hard magnet suitable for applications such as magnetic recording, with TN = 108K. A new phase of CaIr1-xPtxO3 synthesized at a high P/T condition has Raman modes which resemble those of CaIrO3 perovskite, suggesting this phase has a perovskite structure.The instability of the perovskite phase of CaIr1-xPtxO3 reveals why the post-perovskite to peovskite phase transition has not been observed for CaPtO3 unlike the case for CaIrO3, CaRhO3 and CaRuO3.

  4. FlorNExT®, a cloud computing application to estimate growth and yield of maritime pine (Pinus pinaster Ait.) stands in Northeastern Portugal

    Energy Technology Data Exchange (ETDEWEB)

    Barreiro, S.; Rua, J.; Tomé, M.

    2016-07-01

    Aim of the study. To introduce and describe FlorNExT®, a free cloud computing application to estimate growth and yield of maritime pine (Pinus pinaster Ait.) even-aged stands in the Northeast of Portugal (NE Portugal). Area of study: NE Portugal. Material and methods: FlorNExT® implements a dynamic growth and yield modelling framework which integrates transition functions for dominant height (site index curves) and basal area, as well as output functions for tree and stand volume, biomass, and carbon content. Main results: FlorNExT® is freely available from any device with an Internet connection at: http://flornext.esa.ipb.pt/. Research highlights: This application has been designed to make it possible for any stakeholder to easily estimate standing volume, biomass, and carbon content in maritime pine stands from stand data, as well as to estimate growth and yield based on four stand variables: age, density, dominant height, and basal area. FlorNExT® allows planning thinning treatments. FlorNExT® is a fundamental tool to support forest mobilization at local and regional scales in NE Portugal. (Author)

  5. Trabalho em equipe na atenção primária: a experiência de Portugal Teamwork in primary care: the experience of Portugal

    Directory of Open Access Journals (Sweden)

    Marize Barros de Souza

    2013-03-01

    Full Text Available OBJETIVO: Analisar o trabalho em equipe na atenção primária em saúde em Portugal. MÉTODOS: Foi realizada uma pesquisa avaliativa de abordagem qualitativa, com desenho de estudo de caso. Os dados foram obtidos por entrevista semiestruturada, observação direta e análise documental. Foram entrevistados gestores, profissionais e usuários de 11 unidades de saúde familiar (USF portuguesas, totalizando 71 participantes. Utilizou-se a técnica de análise de conteúdo na interpretação das entrevistas. RESULTADOS: Cada equipe era constituída por médico, enfermeiro e funcionário administrativo, atendendo entre 1 250 e 2 060 usuários. Uma característica marcante da experiência portuguesa foi a formação das equipes nas USF de forma voluntária, por meio de afinidades pessoais, com autonomia de composição. Observou-se nessas USF o desenvolvimento de "carteira básica de serviços" juntamente com intervenções de vigilância, promoção da saúde e prevenção de doença, cuidados em situação de doença aguda, acompanhamento clínico de doença crônica e de patologia múltipla, cuidados domiciliares, interligação e colaboração em rede com outros serviços (cuidados hospitalares. Foram relatadas dificuldades no atendimento domiciliar. A informatização era ampla nas USF. De acordo com os entrevistados, as mudanças advindas da implementação das USF foram maior acessibilidade dos usuários aos serviços, maior qualidade do cuidado prestado e trabalho em equipe com objetivos e metas, além da existência de um plano de ação. CONCLUSÕES: Mesmo não tendo assumido um papel de coordenação da rede de cuidados, a atenção primária em saúde organizada a partir de equipes foi avaliada positivamente em Portugal, como promotora de maior acesso, continuidade e humanização dos serviços.OBJECTIVE: To analyze the work of health care teams delivering primary care in Portugal. METHODS: We performed an evaluative research project

  6. Monetary Poverty, Material Deprivation and Consistent Poverty in Portugal

    OpenAIRE

    Carlos Farinha Rodrigues; Isabel Andrade

    2012-01-01

    In this paper we use the Portuguese component of the European Union Statistics on Income and Living Conditions {EU-SILC) to develop a measure of consistent poverty in Portugal. It is widely agreed that being poor does not simply mean not having enough monetary resources. It also reflects a lack of access to the resources required to enjoy a minimum standard of living and participation in the society one belor]gs to. The coexistence of material deprivation and monetary poverty leads ...

  7. Tourist Spaces and Tourism Policy in Spain and Portugal

    OpenAIRE

    Almeida-Garcia, Fernando; Cortes-Macias, Rafael; Balbuena Vázquez, Antonia

    2013-01-01

    This study analyses the relationship between the development of the tourism policy of Spain and Portugal and their effects on regional imbalances. Despite the proximity of the two countries and their specialisation in tourism, there are few comparative studies on tourism of the two Iberian countries. The study focuses on the two major phases of tourism policy: the period of mass tourism and post-Fordist stage. In the conclusions we refer the debate on the existence of a model of development b...

  8. For the greater credibility: Jesuit science and education in modern Portugal (1858-1910).

    Science.gov (United States)

    Malta Romeiras, Francisco

    2018-03-01

    Upon the restoration of the Society of Jesus in Portugal in 1858, the Jesuits founded two important colleges that made significant efforts in the promotion of hands-on experimental teaching of the natural sciences. At the Colégio de Campolide (Lisbon, 1858-1910) and the Colégio de São Fiel (Louriçal do Campo, 1863-1910) the Jesuits created modern chemistry and physics laboratories, organized significant botanical, zoological and geological collections, promoted scientific expeditions with their students to observe eclipses and to collect novel species of animals and plants, and engaged in original research work in physics, botany, and zoology. The successful implementation of modern scientific practices gained these colleges public recognition as the most prominent secondary institutions in nineteenth-century Portugal, and this made a major contribution to countering the widespread and commonly accepted anti-Jesuit accusations of obscurantism and scientific backwardness.

  9. Prevalence and management of cardiovascular risk factors in Portuguese living in Portugal and Portuguese who migrated to Switzerland.

    Science.gov (United States)

    Alves, Luís; Azevedo, Ana; Barros, Henrique; Vollenweider, Peter; Waeber, Gérard; Marques-Vidal, Pedro

    2015-03-31

    Information regarding the health status of migrants compared to subjects who remain in the country of origin is scarce. We compared the levels and management of the main cardiovascular risk factors between Portuguese living in Porto (Portugal) and Portuguese migrants living in Lausanne (Switzerland). Cross-sectional studies conducted in Porto (EPIPorto, 1999 to 2003, n = 1150) and Lausanne (CoLaus, 2003 to 2006, n = 388) among subjects aged 35-65 years. Educational level, medical history and time since migration were collected using structured questionnaires. Body mass index, blood pressure, cholesterol and glucose levels were measured using standardized procedures. Portuguese living in Lausanne were younger, more frequently male and had lower education than Portuguese living in Porto. After multivariate adjustment using Poisson regression, no differences were found between Portuguese living in Porto or in Lausanne: prevalence rate ratio (PRR) and (95% confidence interval) for Portuguese living in Lausanne relative to Portuguese living in Porto: 0.92 (0.71 - 1.18) for current smoking; 0.78 (0.59 - 1.04) for obesity; 0.81 (0.62 - 1.05) for abdominal obesity; 0.82 (0.64 - 1.06) for hypertension; 0.88 (0.75 - 1.04) for hypercholesterolemia and 0.92 (0.49 - 1.73) for diabetes. Treatment and control rates for hypercholesterolemia were higher among Portuguese living in Lausanne: PRR = 1.91 (1.15 - 3.19) and 3.98 (1.59 - 9.99) for treatment and control, respectively. Conversely, no differences were found regarding hypertension treatment and control rates: PRR = 0.98 (0.66 - 1.46) and 0.97 (0.49 - 1.91), respectively, and for treatment rates of diabetes: PRR = 1.51 (0.70 - 3.25). Portuguese living in Lausanne, Switzerland, present a similar cardiovascular risk profile but tend to be better managed regarding hypercholesterolemia than Portuguese living in Porto, Portugal.

  10. Introdução à História Medieval de Portugal

    Directory of Open Access Journals (Sweden)

    Manoela Mendonça

    2006-01-01

    Full Text Available Dans cet article on prétend discuter la question qui motive plusieurs débats académiciens, autrement dit s´ilya eu ou non féodalisme au Portugal et quelles implications qui sont découlant de l´analyse du féodalisme à peine comme une réalité sociale et economique.

  11. JPRS Report, West Europe, Reference Aid, Acronyms and Abbreviations of Portugal

    Science.gov (United States)

    1988-09-02

    Bank of Portugal Portuguese Bank of the Atlantic Banco Portugues de Investimentos Portuguese Investment Bank BPSM Banco Pinto & Sotto Mayor BRI...Pinto & Sotto Mayor Bank Boletim de Registo de Importacao Import Register Bulletin BSB Batalhao de Sapadores Bombeiros fire-fighting battalion...3. Congresso Nacional Africano CNAEBA Conselho Nacional de ^ Alfabetizacao e Educacao de Base de Adultos CNASPEL Comissao Nacional de Apoio e

  12. A Gazeta dos Caminhos de Ferro e a Promoção do Turismo em Portugal (1888-1940).

    OpenAIRE

    Figueiredo Ribeiro, Elói de

    2009-01-01

    Tendo como objecto de estudo a Gazeta dos Caminhos de Ferro pretende-se fazer uma abordagem ao desenvolvimento do turismo em Portugal no período que decorreu entre 1888 e 1940. O levantamento dos vários artigos publicados na Gazeta e as iniciativas dos seus editores para incentivar as viagens turísticas permitem perceber o papel relevante que esta publicação teve no desenvolvimento do turismo em Portugal. Sendo uma publicação dedicada ao caminho-de-ferro a Gazeta traduz a importância que este...

  13. A deficiente informação aumenta os riscos dos pesticidas em Portugal The deficient information increase the pesticides risks in Portugal

    Directory of Open Access Journals (Sweden)

    Pedro Amaro

    2010-12-01

    Full Text Available O risco do uso dos pesticidas agrícolas ser aceitável depende da adopção de rigorosas medidas de segurança definidas pela UE. Esta problemática, em Portugal, é muito preocupante em consequência de graves ilegalidades, como o não funcionamento da CATPF há 5 anos e da sistemática prática, a nível oficial (ex: DGPC/DGADR e Serviços de Avisos e das empresas de pesticidas, da política de esconder a informação essencial para: a selecção dos pesticidas menos perigosos; o conhecimento das indispensáveis medidas de mitigação do risco; e a adequada formação de técnicos e de agricultores.The pesticide risk could be acceptable if mitigation measures decided by EU are adopted. In Portugal that problematic is quite difficult in consequence of graves illegalities, as the CATPF 5 years not working and the systematic practice, at official level (ex: DGPC/DGADR and Warning Service and at pesticides suppliers, of a political to hide the information that is essential to: the pesticides selection of the less dangerous to human health and the environment; the knowledge of indispensable and appropriate measures to reduce those risks as much as possible; and the level of education and training of technicians and farmers.

  14. Formaldehyde and acetaldehyde emissions from residential wood combustion in Portugal

    Science.gov (United States)

    Cerqueira, Mário; Gomes, Luís; Tarelho, Luís; Pio, Casimiro

    2013-06-01

    A series of experiments were conducted to characterize formaldehyde and acetaldehyde emissions from residential combustion of common wood species growing in Portugal. Five types of wood were investigated: maritime pine (Pinus pinaster), eucalyptus (Eucalyptus globulus), cork oak (Quercus suber), holm oak (Quercus rotundifolia) and pyrenean oak (Quercus pyrenaica). Laboratory experiments were performed with a typical wood stove used for domestic heating in Portugal and operating under realistic home conditions. Aldehydes were sampled from diluted combustion flue gas using silica cartridges coated with 2,4-dinitrophenylhydrazine and analyzed by high performance liquid chromatography with diode array detection. The average formaldehyde to acetaldehyde concentration ratio (molar basis) in the stove flue gas was in the range of 2.1-2.9. Among the tested wood types, pyrenean oak produced the highest emissions for both formaldehyde and acetaldehyde: 1772 ± 649 and 1110 ± 454 mg kg-1 biomass burned (dry basis), respectively. By contrast, maritime pine produced the lowest emissions: 653 ± 151 and 371 ± 162 mg kg-1 biomass (dry basis) burned, respectively. Aldehydes were sampled separately during distinct periods of the holm oak wood combustion cycles. Significant variations in the flue gas concentrations were found, with higher values measured during the devolatilization stage than in the flaming and smoldering stages.

  15. Trichinella britovi in a red fox (Vulpes vulpes) from Portugal.

    Science.gov (United States)

    Lopes, Ana Patrícia; Vila-Viçosa, Maria João; Coutinho, Teresa; Cardoso, Luís; Gottstein, Bruno; Müller, Norbert; Cortes, Helder C E

    2015-06-15

    Trichinellosis is one of the most important foodborne parasitic zoonoses, caused by nematodes of the genus Trichinella. Pigs and other domestic and wild animals, including red foxes (Vulpes vulpes), are sources of Trichinella infection for human beings. Trichinella britovi is the major agent of infection in sylvatic animals and the most important species circulating in the European wildlife. The present study aimed at assessing Trichinella spp. infection in red foxes from the North of Portugal. Forty-seven carcasses of wild red foxes shot during the official hunting season or killed in road accidents were obtained between November 2008 and March 2010. In order to identify the presence of Trichinella spp. larvae in red foxes, an individual artificial digestion was performed using approximately 30 g of muscle samples. Larvae of Trichinella spp. were detected in one (2.1%) out of the 47 assessed foxes. After a multiplex polymerase chain reaction analysis, T. britovi was molecularly identified as the infecting species. The recognition of T. britovi in a red fox confirms that a sylvatic cycle is present in the North of Portugal and that the local prevalence of Trichinella infection in wildlife must not be ignored due to its underlying zoonotic risks. Copyright © 2015 Elsevier B.V. All rights reserved.

  16. Spatial and temporal variability of precipitation and drought in Portugal

    Directory of Open Access Journals (Sweden)

    D. S. Martins

    2012-05-01

    Full Text Available The spatial variability of precipitation and drought are investigated for Portugal using monthly precipitation from 74 stations and minimum and maximum temperature from 27 stations, covering the common period of 1941–2006. Seasonal precipitation and the corresponding percentages in the year, as well as the precipitation concentration index (PCI, was computed for all 74 stations and then used as an input matrix for an R-mode principal component analysis to identify the precipitation patterns. The standardized precipitation index at 3 and 12 month time scales were computed for all stations, whereas the Palmer Drought Severity Index (PDSI and the modified PDSI for Mediterranean conditions (MedPDSI were computed for the stations with temperature data. The spatial patterns of drought over Portugal were identified by applying the S-mode principal component analysis coupled with varimax rotation to the drought indices matrices. The result revealed two distinct sub-regions in the country relative to both precipitation regimes and drought variability. The analysis of time variability of the PC scores of all drought indices allowed verifying that there is no linear trend indicating drought aggravation or decrease. In addition, the analysis shows that results for SPI-3, SPI-12, PDSI and MedPDSI are coherent among them.

  17. Spatio-temporal clustering of wildfires in Portugal

    Science.gov (United States)

    Costa, R.; Pereira, M. G.; Caramelo, L.; Vega Orozco, C.; Kanevski, M.

    2012-04-01

    Several studies have shown that wildfires in Portugal presenthigh temporal as well as high spatial variability (Pereira et al., 2005, 2011). The identification and characterization of spatio-temporal clusters contributes to a comprehensivecharacterization of the fire regime and to improve the efficiency of fire prevention and combat activities. The main goalsin this studyare: (i) to detect the spatio-temporal clusters of burned area; and, (ii) to characterize these clusters along with the role of human and environmental factors. The data were supplied by the National Forest Authority(AFN, 2011) and comprises: (a)the Portuguese Rural Fire Database, PRFD, (Pereira et al., 2011) for the 1980-2007period; and, (b) the national mapping burned areas between 1990 and 2009. In this work, in order to complement the more common cluster analysis algorithms, an alternative approach based onscan statistics and on the permutation modelwas used. This statistical methodallows the detection of local excess events and to test if such an excess can reasonably have occurred by chance.Results obtained for different simulations performed for different spatial and temporal windows are presented, compared and interpreted.The influence of several fire factors such as (climate, vegetation type, etc.) is also assessed. Pereira, M.G., Trigo, R.M., DaCamara, C.C., Pereira, J.M.C., Leite, S.M., 2005:"Synoptic patterns associated with large summer forest fires in Portugal".Agricultural and Forest Meteorology. 129, 11-25. Pereira, M. G., Malamud, B. D., Trigo, R. M., and Alves, P. I.: The history and characteristics of the 1980-2005 Portuguese rural fire database, Nat. Hazards Earth Syst. Sci., 11, 3343-3358, doi:10.5194/nhess-11-3343-2011, 2011 AFN, 2011: AutoridadeFlorestalNacional (National Forest Authority). Available at http://www.afn.min-agricultura.pt/portal.

  18. New finds of stegosaur tracks from the Upper Jurassic Lourinhã formation, Portugal

    DEFF Research Database (Denmark)

    Mateus, Octavio; Milàn, Jesper; Romano, Michael

    2011-01-01

    Eleven new tracks from the Upper Jurassic of Portugal are described and attributed to the stegosaurian ichnogenus Deltapodus. One track exhibits exceptionally well−preserved impressions of skin on the plantar surface, showing the stegosaur foot to be covered by closely spaced skin tubercles of ca...

  19. Academic publishing in Portugal: threats and major opportunities

    Directory of Open Access Journals (Sweden)

    Delfim Leão

    2015-03-01

    Full Text Available This article begins with an analysis of the current state of scientific publication in Portugal, with reference to the impact of the open access (OA policies of commercial and academic publishers. It then explores the relationship between academic publishing and institutional repositories, discussing the way they should complement one another, taking as reference the activities of the Portuguese Association of Higher Education Publishers (APEES. Final remarks deal more specifically with the UC Digitalis project from Coimbra University Press (CUP, and the way it is committed to the goal of fostering science produced in Portuguese-speaking countries.

  20. Population dose assessment from radiodiagnosis in Portugal

    International Nuclear Information System (INIS)

    Serro, R.; Carreiro, J.V.; Galvao, J.P.; Reis, R.

    1992-01-01

    A survey of radiodiagnostic installations was carried out in Portugal covering 75 premises including public hospitals, local and regional public health centres. A total of 175 X ray tubes was surveyed using the new NEXT methodology covering data on premises, tube and operator, and projection. Average value of voltage, current-time product, HVL, ratio of beam area to film area and source to film distance for the eleven most frequent projections are reported as well as the skin entrance exposure and the doses to some organs. The weighted average dose values per projection and for the different organs allowed an estimate of the whole-body dose per caput. From the gonadal doses the genetic significant dose was also estimated

  1. Energy efficiency and renewable energy systems in Portugal and Brazil

    DEFF Research Database (Denmark)

    Østergaard, Poul Alberg; Soares, Isabel; Ferreira, Paula

    2014-01-01

    This article presents a review of the energy situation in Brazil and Portugal; two countries which are both characterised by high utilisation of renewable energy sources though with differences between them. The article also introduces contemporary energy research conducted on the two countries...... and presented at The 1st International Congress on Energy & Environment ranging from electricity end-use analyses, electricity production analyses to socio-economic assessment and large-scale energy scenarios....

  2. Being a male nurse in Portugal during Salazar's dictatorship (1940-70).

    Science.gov (United States)

    da Silva, Helena

    2013-06-01

    In several western countries, nursing was clearly seen as an occupation for women. With the creation of the first nursing schools, the gendering of the profession was accelerated. Male nurses' contribution to the development of the profession was limited in comparison with women's. However, the situation was slightly different in Portugal. This article aims at demonstrating a specific example of the gendering of the nursing profession, by simply copying the western model--considered the most developed--without questioning the consequences or even whether it was adapted to the country that had a different nursing tradition. Because the consequences of this gendering are still felt nowadays, this article opens a reflection on how complex it is to follow a foreign nursing model and on the issues associated with such a copy. Qualitative and quantitative analysis of several historical documents and interviews with several retired nurses contributed to an understanding of how men became nurses and how they worked in Portugal, despite gender discrimination, between 1940 and 1970. With different nursing training and job opportunities, Portuguese male nurses still managed to contribute, even beyond that of female nurses, to the improvement of the nursing profession. © 2012 John Wiley & Sons Ltd.

  3. Mycosphaerella and Teratosphaeria species associated with Mycosphaerella Leaf Disease on Eucalyptus globulus in Portugal

    Energy Technology Data Exchange (ETDEWEB)

    Silva, M. C.; Machado, H. N.; Neves, L.; Araujo, C.; Phillips, J. L.

    2012-11-01

    Plantations of Eucalyptus globulus represent the main source of wood for the pulp and paper industry in Portugal and are affected by the complex of Mycosphaerella and Teratosphaeria species (Mycosphaerella leaf disease), which is an important foliage disease worldwide. This disease affect mainly young trees with juvenile-phase foliage, causing premature defoliation, decreased growth and wood production. Species of Mycosphaerella sensu lato reported on eucalypts in Portugal are M. communis, M. heimii, M. lateralis, M. madeirae, M. marksii M. walkeri, T. africana, T. molleriana, T. nubilosa and T. parva. In order to complete the survey, symptomatic leaves were collected from Eucalyptus globulus plantations. Morphological and molecular characterization was used to give an indication of the species occurrence and most frequent species (T. nubilosa) and the composition of the MLD complex that did not change after the latest review. (Author) 28 refs.

  4. DIVERSIDADE E INTERNACIONALIZAÇÃO DA EDUCAÇÃO: OS ESTUDANTES BRASILEIROS EM PORTUGAL

    Directory of Open Access Journals (Sweden)

    Aline Bazzarella Merçon

    2012-06-01

    Full Text Available Este artigo resulta de um trabalho de mestrado em Ciências da Educação e pretendemos apresentar, brevemente, os conceitos e opiniões de diferentes autores sobre a integração, internacionalização da educação e ideais de interculturalidade estabelecidos, entre Portugal e Brasil no ensino superior. Examinamos alguns Acordos e Leis celebrados entre os países com a finalidade de compreendermos o papel social dos mesmos. Buscamos esclarecer como os programas de internacionalização e cooperação para mobilidade estudantil facilitam e estimulam a integração na vida estudantil e o desenvolvimento pessoal e social dos alunos brasileiros, em Portugal, bem como as questões da interculturalidade no sistema educativo universitário português, com base na realidade da Universidade de Aveiro.

  5. First records of crocodyle and pterosaur tracks in the Upper Jurassic of Portugal

    DEFF Research Database (Denmark)

    Mateus, Octavio; Milàn, Jesper

    2010-01-01

    The Upper Jurassic of Portugal has a rich vertebrate fauna well documented from both body and trace fossils. Although the occurrence of crocodyles and pterosaurs is well documented from body fossils, trace fossils from both groups were unknown until now. Here we describe an isolated crocodyle-lik...

  6. Associations between Early Family Risk, Children's Behavioral Regulation, and Academic Achievement in Portugal

    Science.gov (United States)

    Cadima, Joana; Gamelas, Ana M.; McClelland, Megan; Peixoto, Carla

    2015-01-01

    Research Findings: This study examined concurrent associations between family sociodemographic risk, self-regulation, and early literacy and mathematics in young children from Azores, Portugal (N = 186). Family sociodemographic risk was indexed by low maternal education, low family income, and low occupational status. Behavioral aspects of…

  7. Analysis of genuine saving and potential green net national income. Portugal, 1990-2005

    International Nuclear Information System (INIS)

    Mota, Rui Pedro; Domingos, Tiago; Martins, Victor

    2010-01-01

    The context of this paper is the measurement of welfare and weak sustainability (defined as non-declining utility) in dynamic economies, i.e., comprehensive or green accounting. We estimate green net national income (GNNI) and genuine saving (GS) for Portugal, for the years 1990 to 2005, accounting for the disamenity of air pollution emissions, the depreciation of commercial forests and the value of time, discussing the implications of the assumptions underlying the inclusion of these terms in the green accounting model. The influence of short-run cycles is analyzed by estimating GNNI excluding business cycles. Our results suggest that business cycles affect the sustainability message of GNNI. We find that potential GNNI is growing and GS is positive in the analyzed period, thereby not indicating a weak sustainability problem in Portugal, although both depict a trend towards unsustainability. Excluding technological progress there is a contradiction in the sustainability message of GNNI and GS. (author)

  8. Fascist labscapes: geneticists, wheat, and the landscapes of Fascism in Italy and Portugal.

    Science.gov (United States)

    Saraiva, Tiago

    2010-01-01

    This paper explores the role of scientists in the building of fascist regimes in Italy and Portugal by focusing on plant geneticists' participation in the Italian and Portuguese wheat wars for bread self-sufficiency. It looks closely at the work undertaken by Nazareno Strampelli at the National Institute of Genetics for Grain Cultivation (Italy) and by António Sousa da Câmara at the National Agronomic Experiment Station (Portugal), both of whom took wheat as their prime experimental object of genetics research. The main argument is that the production of standardized organisms—the breeder's elite seeds—in laboratory spaces is deeply entangled with their circulation through extended distribution networks that allowed for their massive presence in Italian and Portuguese landscapes such as the Po Valley and the Alentejo. The narrative pays particular attention to the historical development of fascist regimes in the two countries, advancing the argument that breeders' artifacts were key components of the institutionalization of the new political regimes.

  9. Analysis of genuine saving and potential green net national income. Portugal, 1990-2005

    Energy Technology Data Exchange (ETDEWEB)

    Mota, Rui Pedro; Domingos, Tiago [Environment and Energy Section, DEM, Instituto Superior Tecnico (Portugal); Martins, Victor [Department of Economics, Instituto Superior de Economia e Gestao (Portugal)

    2010-08-15

    The context of this paper is the measurement of welfare and weak sustainability (defined as non-declining utility) in dynamic economies, i.e., comprehensive or green accounting. We estimate green net national income (GNNI) and genuine saving (GS) for Portugal, for the years 1990 to 2005, accounting for the disamenity of air pollution emissions, the depreciation of commercial forests and the value of time, discussing the implications of the assumptions underlying the inclusion of these terms in the green accounting model. The influence of short-run cycles is analyzed by estimating GNNI excluding business cycles. Our results suggest that business cycles affect the sustainability message of GNNI. We find that potential GNNI is growing and GS is positive in the analyzed period, thereby not indicating a weak sustainability problem in Portugal, although both depict a trend towards unsustainability. Excluding technological progress there is a contradiction in the sustainability message of GNNI and GS. (author)

  10. As funções da resposabilidade social no marketing social de hoje : o caso de estudo McDonald's Portugal

    OpenAIRE

    Marco, Débora Alexandra Rodrigues do

    2012-01-01

    No âmbito deste trabalho propomo-nos elaborar um estudo sobre o conceito da Responsabilidade Social Empresarial em Portugal, compreender a sua relação com o Marketing Social e ilustrar algumas das vantagens inerentes à adopção de um comportamento empresarial socialmente responsável, que contribui por sua vez para o entendimento, comunicação, divulgação e crescimento desta estratégia empresarial em Portugal. A União Europeia desempenha um papel fundamental para o crescimento do ...

  11. Childbearing across borders: Fertility and parenthood attitudes and decisions among breast cancer survivors in USA and Portugal.

    Science.gov (United States)

    Gonçalves, Vânia; Hudson, Janella; Canavarro, Maria Cristina; Morris, Julie; Lee, M Catherine; Donovan, Kristine A; Sutton, Steven K; Vadaparampil, Susan T; Quinn, Gwendolyn P

    2018-04-16

    To compare fertility and childbearing attitudes and decisions of Portuguese and American female reproductive aged breast cancer survivors. This was a cross-sectional study of 102 young breast cancer survivors (59 from Portugal and 43 from USA). Demographic, clinical and reproductive information were collected. Fertility and parenthood attitudes and decisions were assessed through a self-report questionnaire devised specifically for the study. Fertility issues became very important after the diagnosis for most of the women (51%). Few differences existed between USA and Portuguese participants. USA participants were more likely to undergo FP (23% USA vs Portugal 5%, p = 0.01). Portuguese women were more dissatisfied with their physician's explanations about fertility (Portugal: 23% vs USA: 3%; p = 0.01). Overall, women relied on their oncologist for fertility information (70%); only Portuguese women discussed fertility with their family medicine physician (11%). Overall, women showed positive attitudes towards motherhood. Portuguese women were more likely to report their partners placed more value on the family after their illness (Portuguese agree: 55% vs USA agree: 14%; p USA and Portuguese samples were found on fertility and childbearing attitudes and decisions. Copyright © 2018 Elsevier Ltd. All rights reserved.

  12. Association between cardiovascular disease and socioeconomic level in Portugal.

    Science.gov (United States)

    Ribeiro, Sónia; Furtado, Cláudia; Pereira, João

    2013-11-01

    Cardiovascular disease is the leading cause of morbidity, mortality and disability in Portugal. Socioeconomic level is known to influence health status but there is scant evidence on socioeconomic inequalities in cardiovascular disease in Portugal. To analyze the distribution of cardiovascular disease in the Portuguese population according to socioeconomic status. We conducted a cross-sectional study using data from the fourth National Health Survey on a representative sample of the Portuguese population. Socioeconomic inequalities in cardiovascular disease, risk factors and number of medical visits were analyzed using odds ratios according to socioeconomic status (household equivalent income) in the adult population (35-74 years). Comparisons focused on the top and bottom 50% and 10% of household income distribution. Of the 21 807 individuals included, 53.3% were female, and mean age was 54 ± 11 years. Cardiovascular disease, stroke, ischemic heart disease, hypertension, diabetes, obesity and physical inactivity were associated with lower socioeconomic status, while smoking was associated with higher status; number of medical visits and psychological distress showed no association. When present, inequality was greater at the extremes of income distribution. The results reveal an association between morbidity, lifestyle and socioeconomic status. They also suggest that besides improved access to effective medical intervention, there is a need for a comprehensive strategy for health promotion and disease prevention that takes account of individual, cultural and socioeconomic characteristics. Copyright © 2012 Sociedade Portuguesa de Cardiologia. Published by Elsevier España. All rights reserved.

  13. Blepharitis due to in a cat from northern Portugal

    Directory of Open Access Journals (Sweden)

    Paulo Pimenta

    2015-07-01

    Full Text Available Case summary We report a clinical case of blepharitis due to Cryptococcus neoformans yeasts in a 2-year-old stray cat from northern Portugal (Vila Real without concurrent naso-ocular signs. Ophthalmological examination revealed mucopurulent discharge from an open wound in the right upper and lower lids. Slit-lamp biomicroscopy showed a normal anterior segment, and intraocular pressure was within the normal reference interval. No fundoscopic alterations were detected in either eye by direct and indirect ophthalmoscopic examination. Cytological examination of an appositional smear showed numerous polymorphic neutrophils and macrophages, together with spherical yeast cells compatible with Cryptococcus species. Molecular analysis by means of PCR and restriction fragment length polymorphism identified C neoformans genotype VNI. The cat was treated with itraconazole, and amoxicillin and clavulanic acid, combined with a commercial ear ointment and an imidacloprid/moxidectin spot-on application for bilateral parasitic otitis caused by Otodectes cynotis . One month after treatment, the clinical signs were completely resolved. Localised cutaneous lesions, as in the present case, probably result from contamination of cat-scratch injuries with viable encapsulated yeasts. Relevance and novel information This is, to the best of our knowledge, the first clinical report of feline blepharitis due to C neoformans without concurrent naso-ocular signs. The current findings, together with those from recent reports of the infection in domestic animals, should alert the veterinary community both in Portugal and in Europe to this underdiagnosed disease.

  14. Level of commitment of the fans of the Thermas of Centre of Portugal in Facebook

    Directory of Open Access Journals (Sweden)

    Maria Filomena Torres

    2016-05-01

    Full Text Available Social networks like Facebook have revolutionized communication strategies of the brands and its effects are clear and deep, and have transformed the way in which society is communicated to changed perceptions and social norms and, therefore, have transformed the dynamics of communication. In this sense, it is pertinent to analyze the presence of Termas of Centre of Portugal in social networks is essential, once that allows them to transmit information about their services and products.  The aim of this study is to measure, through digital indicators, the level of interaction of the Termas of Centre of Portugal (in the official pages of Facebook with his audience, in order to compare and measure the participation and interaction of each one of the pages with their users, and thus help managers to develop content strategies that make possible increasing the level of participation of the fans to the brand. The choice of Termas which are establishments where health care is provided, in which it is performed harnessing the therapeutic properties of a medicinal mineral water for prevention of ailments, therapeutic, etc., it is based on the importance today is acquiring health tourism in Portugal, being Termas its main representative. The working methodology is based on quantitative analysis using the analysis of digital metrics PageMarch and Kaushik together with an analysis of the content of the official website of Termas on Facebook. The sampling process was non-probabilistic intentional and collection was carried out between June and October 2015.It is observed that the amount of information available on the pages, just for them, is not responsible for the increased level of commitment. It was verified that most of the pages of the Termas of Centre of Portugal on Facebook, do not take this tool, which Facebook has become, in order to communicate through Electronic Word-of-mouse with your audience.

  15. A new species of Speonemadus from Portugal, with the revision of the escalerai-group (Coleoptera, Leiodidae

    Directory of Open Access Journals (Sweden)

    Ana Sofia P.S. Reboleira

    2017-01-01

    Full Text Available Over recent years, intense field work in caves of Portugal has provided new data on the distribution of subterranean Iberian leiodid beetles. Speonemadus algarvensis sp. nov. is described from caves of southern Portugal. The new species is included in the Speonemadus Jeannel, 1922 escalerai-group (Cholevinae; Anemadini. All species of the S. escalerai-group are revised and S. breuili (Jeannel, 1922 is resurrected as a valid species. A key to identify the species of the S. escalerai-group is provided and the distinctive characters are illustrated. The distribution of all species of the group is mapped with new data together with biogeographic considerations.

  16. A salinização do solo em Portugal: Causas, extensão e soluções

    OpenAIRE

    Gonçalves, M. C.; Martins, J. C.; Ramos, T. B.

    2015-01-01

    A salinização é um dos principais processosde degradação do solo a nível mundial. Em Portugal, este problema está limitado às zonas costeiras afectadas pelas marés (sapais) e a algumas áreas regadas no sul do País. Contudo, o aumento da área regada e as perspectivas de mudanças climáticas para as próximas décadas, nomeadamente o aumento das temperaturas, podem levar a um acréscimo da área afectada por aquele problema em Portugal e a uma crescente degradação dos solos. Descrevem-se as principa...

  17. FlorNExT®, a cloud computing application to estimate growth and yield of maritime pine (Pinus pinaster Ait. stands in Northeastern Portugal

    Directory of Open Access Journals (Sweden)

    Fernando Pérez-Rodríguez

    2016-07-01

    Full Text Available Aim of the study: To introduce and describe FlorNExT®, a free cloud computing application to estimate growth and yield of maritime pine (Pinus pinaster Ait. even-aged stands in the Northeast of Portugal (NE Portugal. Area of study: NE Portugal. Material and methods: FlorNExT® implements a dynamic growth and yield modelling framework which integrates transition functions for dominant height (site index curves and basal area, as well as output functions for tree and stand volume, biomass, and carbon content. Main results: FlorNExT® is freely available from any device with an Internet connection at: http://flornext.esa.ipb.pt/. Research highlights: This application has been designed to make it possible for any stakeholder to easily estimate standing volume, biomass, and carbon content in maritime pine stands from stand data, as well as to estimate growth and yield based on four stand variables: age, density, dominant height, and basal area. FlorNExT® allows planning thinning treatments. FlorNExT® is a fundamental tool to support forest mobilization at local and regional scales in NE Portugal. Keywords: forest management; maritime pine; forest modelling; knowledge transfer tool.

  18. Assessment of forest biomass for use as energy. GIS-based analysis of geographical availability and locations of wood-fired power plants in Portugal

    Science.gov (United States)

    H. Viana; Warren B. Cohen; D. Lopes; J. Aranha

    2010-01-01

    Following the European Union strategy concerning renewable energy (RE), Portugal established in their national policy programmes that the production of electrical energy from RE should reach 45% of the total supply by 2010. Since Portugal has large forest biomass resources, a significant part of this energy will be obtained from this source. In addition to the two...

  19. Redox-sensitive self-assembled nanoparticles based on alpha-tocopherol succinate-modified heparin for intracellular delivery of paclitaxel.

    Science.gov (United States)

    Yang, Xiaoye; Cai, Xiaoqing; Yu, Aihua; Xi, Yanwei; Zhai, Guangxi

    2017-06-15

    To remedy the problems riddled in cancer chemotherapy, such as poor solubility, low selectivity, and insufficient intra-cellular release of drugs, novel heparin-based redox-sensitive polymeric nanoparticles were developed. The amphiphilic polymer, heparin-alpha-tocopherol succinate (Hep-cys-TOS) was synthesized by grafting hydrophobic TOS to heparin using cystamine as the redox-sensitive linker, which could self-assemble into nanoparticles in phosphate buffer saline (PBS) with low critical aggregation concentration (CAC) values ranging from 0.026 to 0.093mg/mL. Paclitaxel (PTX)-loaded Hep-cys-TOS nanoparticles were prepared via a dialysis method, exhibiting a high drug-loading efficiency of 18.99%. Physicochemical properties of the optimized formulation were characterized by dynamic light scattering (DLS), transmission electron microscope (TEM) and differential scanning calorimetry (DSC). Subsequently, the redox-sensitivity of Hep-cys-TOS nanoparticles was confirmed by the changes in size distribution, morphology and appearance after dithiothreitol (DTT) treatment. Besides, the in vitro release of PTX from Hep-cys-TOS nanoparticles also exhibited a redox-triggered profile. Also, the uptake behavior and pathways of coumarin 6-loaded Hep-cys-TOS nanoparticles were investigated, suggesting the nanoparticles could be taken into MCF-7 cells in energy-dependent, caveolae-mediated and cholesterol-dependent endocytosis manners. Later, MTT assays of different PTX-free and PTX-loaded formulations revealed the desirable safety of PTX-free nanoparticles and the enhanced anti-cancer activity of PTX-loaded Hep-cys-TOS nanoparticles (IC 50 =0.79μg/mL). Apoptosis study indicated the redox-sensitive formulation could induce more apoptosis of MCF-7 cells than insensitive one (55.2% vs. 41.7%), showing the importance of intracellular burst release of PTX. Subsequently, the hemolytic toxicity confirmed the safety of the nanoparticles for intravenous administration. The results

  20. Continuing Vocational Training in Local Government in Portugal, 2000-05--What Has Changed?

    Science.gov (United States)

    Cabrito, Belmiro Gil; Simao, Ana Margarida Veiga; Alves, Mariana Gaio; Almeida, Antonio

    2009-01-01

    Local government in Portugal had a good opportunity to modernise through the Programa de Formacao para as Autarquias Locais (Foral) [Training programme for local authorities], implemented between 2000 and 2005. Substantial financial resources were made available through the programme to retrain local government human resources in order to improve…

  1. Genetic characterization of Toxoplasma gondii isolates from Portugal, Austria and Israel reveals higher genetic variability within the type II lineage.

    Science.gov (United States)

    Verma, S K; Ajzenberg, D; Rivera-Sanchez, A; Su, C; Dubey, J P

    2015-06-01

    This study compared genetic diversity of Toxoplasma gondii isolates from Portugal, Austria and Israel. For this, we genotyped 90 T. gondii isolates (16 from Portugal, 67 from Austria and 7 from Israel) using 10 nested PCR-restriction length polymorphism (RFLP) genetic markers and 15 microsatellite (MS) markers. By PCR-RFLP typing, 7 isolates from Portugal chickens were identified as type II (ToxoDB #1 or #3), 4 were type III (ToxoDB #2) and the remaining 4 isolates have unique genotype pattern were designated as ToxoDB #254. One mouse virulent isolate from a bovine fetus (Bos taurus) in Portugal was type I (ToxoDB #10) at all loci and designated as TgCowPr1. All 67 isolates from Austria and 7 from Israel were type II (ToxoDB #1 or #3). By MS typing, many additional genetic variations were revealed among the type II and type III isolates. Phylogenetic analysis showed that isolates from the same geographical locations tend to cluster together, and there is little overlapping of genotypes among different locations. This study demonstrated that the MS markers can provide higher discriminatory power to reveal association of genotypes with geographical locations. Future studies of the type II strains in Europe by these MS markers will be useful to reveal transmission patterns of the parasite.

  2. Plano de social media marketing para a TAP Portugal

    OpenAIRE

    Lopes, Andreia Cristina Figueiredo

    2014-01-01

    Mestrado em Marketing O social media marketing adquire cada vez maior relevo para as empresas e exige, tal como noutras áreas de marketing, a delineação de um plano estratégico por forma a potenciar o seu sucesso. Tomando como objecto de estudo a companhia aérea TAP Portugal, foi elaborado um Plano de Social Media Marketing, com base no modelo conceptual de Barker et al. (2013), designado de "Social Media Planning Cycle". Para a elaboração do Plano, foram recolhidos dados primários, seguin...

  3. Medieval codes of ius commune in Portugal: status quaestionis

    Directory of Open Access Journals (Sweden)

    José Domingues

    2016-12-01

    Full Text Available Portugal inherited from the kingdom of León legal sources and its earliest law code. With the “rebirth” of Roman law, the Ius commune –arriving very early in the twelfth century– soon came to shape everyday life, from the middle ages until the Enlightenment of the late eighteenth century. Enormous research efforts have been made to locate chronologically and spatially medieval remnants of these legal texts. This work aims to provide a summary, including a comprehensive and updated picture, of the status quaestionis of this theme.

  4. Monitorização da força da ondulação na base da arriba (Pessegueiro, SW Portugal. Primeiros resultados

    Directory of Open Access Journals (Sweden)

    Mário Neves

    1997-11-01

    Full Text Available MEASUREMENT OF THE WAVE FORCE AT THE CLIFF BASE (PESSEGUEIRO, SW PORTUGAL. FIRST RESULTS. In this article the characteristicsof a new wave force sensor (EWIN are briefly described. This instrument was bolted to the shore platform of Pessegueiro on a first trial experience in Portugal. The maximum wave force records are also analysed in correlation with the wave climate accured in these occasions.

  5. Educational technology in care management: technological profile of nurses in Portuguese hospitals.

    Science.gov (United States)

    Landeiro, Maria José Lumini; Freire, Rosa Maria Albuquerque; Martins, Maria Manuela; Martins, Teresa Vieira; Peres, Heloísa Helena Ciqueto

    2015-12-01

    Objective To identify the technological profile of nurses in Portuguese hospitals. Method A quantitative exploratory study conducted in two hospitals in the northern region and one in the central region of Portugal. The sample was randomly selected and included 960 nurses. Results Of the participants, 420 (46.1%) used computers, 196 (23.4%) reported having knowledge about using computers for teaching, 174 (21.1%) used computers to teach, 112 (15.1%) recognized that using computers can be a technological means to supplement classroom training, 477 (61.6%) would like to receive training on using computers, and 382 (40.9%) reported self-learning of information technology. In relation to distance education, 706 (74.9%) reported they were familiar with it and 752 (76.4%) indicated an interest in participating in training using this modality. Conclusion Organizations should be mindful of the technological profile shown by this group of nurses and look for ways to introduce educational technologies in the management of care.

  6. Driver mutations (JAK2V617F, MPLW515L/K or CALR, pentraxin-3 and C-reactive protein in essential thrombocythemia and polycythemia vera

    Directory of Open Access Journals (Sweden)

    Federico Lussana

    2017-02-01

    Full Text Available Abstract Background The driver mutations JAK2V617F, MPLW515L/K and CALR influence disease phenotype of myeloproliferative neoplasms (MPNs and might sustain a condition of chronic inflammation. Pentraxin 3 (PTX3 and high-sensitivity C-reactive protein (hs-CRP are inflammatory biomarkers potentially useful for refining prognostic classification of MPNs. Methods We evaluated 305 with essential thrombocythemia (ET and 172 polycythemia vera (PV patients diagnosed according to the 2016 WHO criteria and with full molecular characterization for driver mutations. Results PTX3 levels were significantly increased in carriers of homozygous JAK2V617F mutation compared to all the other genotypes and triple negative ET patients, while hs-CRP levels were independent of the mutational profile. The risk of haematological evolution and death from any cause was about 2- and 1.5-fold increased in individuals with high PTX-3 levels, while the thrombosis rate tended to be lower. High hs-CRP levels were associated with risk of haematological evolution, death and also major thrombosis. After sequential adjustment for potential confounders (age, gender, diagnosis and treatments and the presence of JAK2V617F homozygous status, high hs-CRP levels remained significant for all outcomes, while JAK2V617F homozygous status as well as treatments were the factors independently accounting for adverse outcomes among patients with high PTX3 levels. Conclusions These results provide evidence that JAK2V617F mutation influences MPN-associated inflammation with a strong correlation between allele burden and PTX3 levels. Plasma levels of hs-CRP and PTX3 might be of prognostic value for patients with ET and PV, but their validation in future prospective studies is needed.

  7. Incidence and prevalence of hypercholesterolemia in Portugal: a systemic review. Part II.

    Science.gov (United States)

    Costa, João; Borges, Margarida; Oliveira, Eduardo; Gouveia, Miguel; Carneiro, António Vaz

    2003-05-01

    Over 50% of the mortality and disability caused by ischemic heart disease and stroke could be avoided by controlling individual risk factors (hypertension, hypercholesterolemia, smoking and obesity). The ignorance of the extent and impact of hypercholesterolemia (HC) in Portugal prompted us to undertake this systematic review of the prevalence and incidence of hyperlipidemia in Portugal, based exclusively on work published nationally. We included every study published in the country that could provide data on the prevalence or incidence of hypercholesterolemia. The search strategy included an electronic search of national and international biomedical databases (Medline, Index Revistas Médicas Portuguesas, the Portuguese Directorate-General for Health and the Portuguese National School of Public Health), screening of reference lists from the individual studies, and personal contacts with institutions, groups and authors (such as the Portuguese Foundation of Cardiology). The data--recorded in electronic format--was collected independently by two of the authors (JC and MB), with consensus achieved with a third (AVC) when there were differences in the study coding. We could only identify one paper on the incidence of HC in Portugal, which gave an incidence of 559 new cases per 100,000 inhabitants, increasing with age up to 54 years for men and 64 years for women. There was a higher incidence in men than in women up to the age of 54, but at more advanced ages this relationship was reversed. Prevalence studies on HC included 53,445 individuals overall, with sample size lower than 1000 in most of the individual studies. The most frequently used criterion for HC was > 200 mg/dL, with the mean level being higher in most studies. We calculated the mean prevalence for several cut-off points (190 mg/dL: 63.8%; 200 mg/dL: 56.7%; 240 mg/dL: 31.7%; 250 mg/dL: 21%). Due to the heterogeneity of the data, these results are to be interpreted with caution, even though they are

  8. Incidence and prevalence of hypercholesterolemia in Portugal: a systematic review. Part I.

    Science.gov (United States)

    Costa, João; Borges, Margarida; Oliveira, Eduardo; Gouveia, Miguel; Carneiro, António Vaz

    2003-04-01

    Over 50% of the mortality and disability caused by ischemic heart disease and stroke could be avoided by controlling individual risk factors (hypertension, hypercholesterolemia, smoking and obesity). The ignorance of the extent and impact of hypercholesterolemia (HC) in Portugal prompted us to undertake this systematic review of the prevalence and incidence of hyperlipidemia in Portugal, based exclusively on work published nationally. We included every study published in the country that could provide data on the prevalence or incidence of hypercholesterolemia. The search strategy included an electronic search of national and international biomedical databases (Medline, Index Revistas Médicas Portuguesas, the Portuguese Directorate-General for Health and the Portuguese National School of Public Health), screening of reference lists from the individual studies, and personal contacts with institutions, groups and authors (such as the Portuguese Foundation of Cardiology). The data--recorded in electronic format--was collected independently by two of the authors (JC and MB), with consensus achieved with a third (AVC) when there were differences in the study coding. We could only identify one paper on the incidence of HC in Portugal, which gave an incidence of 559 new cases per 100,000 inhabitants, increasing with age up to 54 years for men and 64 years for women. There was a higher incidence in men than in women up to the age of 54, but at more advanced ages this relationship was reversed. Prevalence studies on HC included 53,445 individuals overall, with sample size lower than 1000 in most of the individual studies. The most frequently used criterion for HC was > 200 mg/dL, with the mean level being higher in most studies. We calculated the mean prevalence for several cut-off points (190 mg/dL: 63.8%; 200 mg/dL: 56.7%; 240 mg/dL: 31.7%; 250 mg/dL: 21%). Due to the heterogeneity of the data, these results are to be interpreted with caution, even though they are

  9. The Guarda structure (Portugal): Impact structure or not? Microstructural studies of Quartz, Zircon and Monazite

    NARCIS (Netherlands)

    Zalinge, M.E. van; Hamers, M.F.; Drury, M.R.

    2012-01-01

    The Guarda Structure in north-eastern Portugal has been proposed as a potential impact structure. We have studied the structure in detail, but no field or microscopic evidence has been found to support the impact hypothesis

  10. Teacher Education in Portugal: Analysing Changes using the ATEE-RDC19 Scenario Methodology.

    Science.gov (United States)

    Sousa, Jesus Maria

    2003-01-01

    Reviews the development of teacher education in Portugal since the 1974 revolution, which brought the country to democracy. Using the Association for Teacher Education in Europe's scenario model, the paper describes the hidden philosophies underlying changes that are occurring and shows how teacher education has evolved from a romantic, idealistic…

  11. Patients’ and physicians’ preferences for type 2 diabetes mellitus treatments in Spain and Portugal: a discrete choice experiment

    Directory of Open Access Journals (Sweden)

    Morillas C

    2015-10-01

    Full Text Available Carlos Morillas,1 Rosa Feliciano,2 Pablo Fernández Catalina,3 Carla Ponte,4 Marta Botella,5 João Rodrigues,6 Enric Esmatjes,7 Javier Lafita,8 Luis Lizán,9 Ignacio Llorente,10 Cristóbal Morales,11 Jorge Navarro-Pérez,12 Domingo Orozco-Beltran,13 Silvia Paz,9 Antonio Ramirez de Arellano,14 Cristina Cardoso,15 Maribel Tribaldos Causadias9 1Hospital Universitario Dr Peset, Valencia, Spain; 2USF São Domingos, Santarém, Portugal; 3Hospital Montecelo de Pontevedra, Galicia, Spain; 4USF Porta do Sol, Matosinhos, Portugal; 5Hospital Universitario Principe de Asturias, Madrid, Spain; 6USF Serra da Lousã, Lousã, Portugal; 7Hospital Clinic, Barcelona, Spain; 8Hospital de Navarra, Navarra, Spain; 9Outcomes’10, Universidad Jaume I, Castellón, Spain; 10Hospital Universitario Nuestra Señora de la Candelaria, Canarias, Spain; 11Hospital Universitario Virgen de la Macarena, Sevilla, Spain; 12INCLIVA, CIBERESP, Universidad de Valencia, Valencia, Spain; 13Sociedad Española de Medicina Familiar y Comunitaria, Valencia, Spain; 14Novo Nordisk EU-HEOR Europe, Madrid, Spain; 15Novo Nordisk, Lisbon, Portugal Objective: To assess Spanish and Portuguese patients’ and physicians’ preferences regarding type 2 diabetes mellitus (T2DM treatments and the monthly willingness to pay (WTP to gain benefits or avoid side effects.Methods: An observational, multicenter, exploratory study focused on routine clinical practice in Spain and Portugal. Physicians were recruited from multiple hospitals and outpatient clinics, while patients were recruited from eleven centers operating in the public health care system in different autonomous communities in Spain and Portugal. Preferences were measured via a discrete choice experiment by rating multiple T2DM medication attributes. Data were analyzed using the conditional logit model.Results: Three-hundred and thirty (n=330 patients (49.7% female; mean age 62.4 [SD: 10.3] years, mean T2DM duration 13.9 [8.2] years, mean body

  12. Cloud-to-ground lightning in Portugal: patterns and dynamical forcing

    Science.gov (United States)

    Santos, J. A.; Reis, M. A.; Sousa, J.; Leite, S. M.; Correia, S.; Janeira, M.; Fragoso, M.

    2012-03-01

    An analysis of the cloud-to-ground discharges (CGD) over Portugal is carried out using data collected by a network of sensors maintained by the Portuguese Meteorological Institute for 2003-2009 (7 yr). Only cloud-to-ground flashes are considered and negative polarity CGD are largely dominant. The total number of discharges reveals a considerable interannual variability and a large irregularity in their distribution throughout the year. However, it is shown that a large number of discharges occur in the May-September period (71%), with a bimodal distribution that peaks in May and September, with most of the lightning activity recorded in the afternoon (from 16:00 to 18:00 UTC). In spring and autumn the lightning activity tends to be scattered throughout the country, whereas in summer it tends to be more concentrated over northeastern Portugal. Winter generally presents low lightning activity. Furthermore, two significant couplings between the monthly number of days with discharges and the large-scale atmospheric circulation are isolated: a regional forcing, predominantly in summer, and a remote forcing. In fact, the identification of daily lightning regimes revealed three important atmospheric conditions for triggering lightning activity: regional cut-off lows, cold troughs induced by remote low pressure systems and summertime regional low pressures at low-tropospheric levels combined with a mid-tropospheric cold trough.

  13. The market features of imported non-indigenous polychaetes in Portugal and consequent ecological concerns

    Directory of Open Access Journals (Sweden)

    Pedro Fidalgo e Costa

    2006-12-01

    Full Text Available The importance of the market for polychaetes dramatically increased after the discovery of their potential as food in aquaculture. In Portugal, the gathering of polychaetes solely from natural populations is not sufficient to meet market demand, both as bait for sea anglers and as a food item in aquaculture. The requests for worms to polychaete dealers by Portuguese and Spanish seafarms have increased during recent years. Due to the lack of intensive culture of these worms in Portugal and the proximity of southern Spanish farms, a large component of imported polychaetes that arrive in Portugal at Lisbon Airport go directly to Spain by road. In 2002 and 2003 a total of 12,728,379 and 16,866,839 polychaetes respectively were imported to Europe via Lisbon Airport from China and the USA. In 2003 the imports from China and the USA realised 716,180 and 291,845 US dollars respectively. Two species were reported to have been imported in these years, namely the Korean blue ragworm Perinereis aibuhitensis and the American bloodworm Glycera dibranchiata. Imports of non-indigenous species, which are traded and sold alive, may increase the risk of accidental introduction into the wild. This is of special concern as Perinereis aibuhitensis has been successfully reared in captivity within the range of environmental conditions existing in the Ria Formosa coastal lagoon. Other risks associated with introduced species are the transport of foreign pathogens and other associated non-native organisms, which may act as carriers of disease.

  14. Characterization of antibiotic resistant enterococci isolated from untreated waters for human consumption in Portugal.

    Science.gov (United States)

    Macedo, Ana S; Freitas, Ana R; Abreu, Cristina; Machado, Elisabete; Peixe, Luísa; Sousa, João C; Novais, Carla

    2011-01-31

    Untreated drinking water is frequently overlooked as a source of antibiotic resistance in developed countries. To gain further insight on this topic, we isolated the indicator bacteria Enterococcus spp. from water samples collected in wells, fountains and natural springs supplying different communities across Portugal, and characterized their antibiotic resistance profile with both phenotypic and genetic approaches. We found various rates of resistance to seven antibiotic families. Over 50% of the isolates were resistant to at least ciprofloxacin, tetracyclines or quinupristin-dalfopristin and 57% were multidrug resistant to ≥3 antibiotics from different families. Multiple enterococcal species (E. faecalis, E. faecium, E. hirae, E. casseliflavus and other Enterococcus spp) from different water samples harbored genes encoding resistance to tetracyclines, erythromycin or gentamicin [tet(M)-46%, tet(L)-14%, tet(S)-5%, erm(B)-22%, aac(6´)-Ie-aph(2″)-12%] and putative virulence factors [gel-28%, asa1-16%]. The present study positions untreated drinking water within the spectrum of ecological niches that may be reservoirs of or vehicles for antibiotic resistant enterococci/genes. These findings are worthy of attention as spread of antibiotic resistant enterococci to humans and animals through water ingestion cannot be dismissed. Copyright © 2010 Elsevier B.V. All rights reserved.

  15. Education and Political Participation of Women: The Case of Portugal

    OpenAIRE

    David, Fátima; Morais, Joana; Abreu, Rute; Marques, Lúcia; Segura, Liliane

    2016-01-01

    This research aims to analyses the women’s participation in Portugal politics in consequence of its educational attainment. On the one hand, the Constitution of the Portuguese Republic of April 2, 1976, gives women (and men) a right to equal opportunities for school success, to access to the higher education and to better working conditions. On the other hand, the same Constitution defends, in article 9, that fundamental task of the State is to promote equality between men and women and, in a...

  16. Prevalência de anticorpos para chlamydia trachomatis em grupos populacionais do Brasil, Inglaterra e Portugal

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    Marluísa de Oliveira Guimarães Ishak

    1988-02-01

    Full Text Available A prevalência de anticorpos IgG, grupo-específico para Chlamydia, em populações do Brasil, Inglaterra e Portugal foi determinada através do teste de imunofluorescência indireta, tendo-se como antígeno a cepa SA2 (f. Foram considerados positivos os soros com títulos de IgG >1:32. Dentre as populações brasileiras, a prevalência de anticorpos para Chlamydia foi maior em Serra Norte (76,2%, p < 0,01 do que nas das populações de Belém (53,6% e dos Índios Xicrins (51,3%. Entre os pacientes do Departamento de Medicina Genito-Urinária do University College Hospital (UCH e do quadro do mesmo Hospital, a prevalência de anticorpos anti-Chlamydia foi de 62% e 53,1%, respectivamente. Anticorpos anti-Chlamydia foram detectados em 54% e 66% na Inglaterra e em 56% e 68% em Portugal, nas pacientes do sexo feminino que freqüentavam Clínicas de Pré-Natal e de Infertilidade, respectivamente, Os resultados encontrados mostram uma alta exposição das populações testadas, à Chlamydia, principalmente do grupo de baixo nível sócio-econômico de Serra Norte, Brasil. A evidência de infecção por Chlamydia é da mesma ordem, tanto no Brasil, quanto na Inglaterra e Portugal.

  17. Cross-border mobility of workers between Galicia and north of Portugal

    Directory of Open Access Journals (Sweden)

    Jorge Falagán Mota

    2013-07-01

    Full Text Available In this paper we deal with cross-border flows of people within the Euroregion Galicia-North of Portugal, paying particular attention to those led by workers. Based on data for daily mobility between the places of residence and work (commuters, it can be defined, within this territory, the so-called Polycentric Urban Regions (PUR of Vigo and Porto. These regions should constitute significant referents of cross-border mobility, whose importance we begin to realize by estimating the movement of passengers across border crossings linking the south of Galicia and the north of Portugal. In this context, given the non-existence of official statistics, the reports prepared by the Eures Galicia/Região Norte office provide relevant information about the flow of cross-border workers in the area, which we have complemented by conducting two surveys directed, respectively, to involved workers and companies, and data from a recent study on labour mobility in the Euroregion. The evidence demonstrates the quantitative importance achieved in the territory analyzed by this interesting phenomenon of cross-border work and allows a description of its characteristics that shows the difficulties faced by the process of construction of a European labor market.

  18. Occult pneumothoraces in acute trauma patients.

    Science.gov (United States)

    Ernst, Amy A; McIntyre, William A; Weiss, Steven J; Berryman, Chad

    2012-11-01

    Many traumatic pneumothoraces (PTX) are not seen on initial chest radiograph (CR) (occult PTX) but are detected only on computed tomography (CT). Although CR remains the first tool for detecting PTX, most trauma patients with significant thoracoabdominal injuries will receive both CT and CR. The primary objective of this study was to retrospectively determine the effectiveness of CR for detecting PTX in trauma patients. Our hypotheses were that CR is a sensitive indicator of PTX on CT, that chest pain and shortness of breath are good predictors of PTX on CR, and that we could determine other predictors of PTX on CR. All trauma patients presenting to our Level I trauma center with a CT-diagnosed PTX over a 2-year period who had both a CR and a chest CT were included. The CT reading was considered the gold standard for PTX diagnosis. Electronic medical records were searched using key words for diagnoses, symptoms, demographics, and radiologic results. We recorded the official radiologist readings for both CR and CT (positive or negative) and the size of the PTX on CT (large, moderate, small, or tiny). The outcome variable was dichotomized based on presence or absence of PTX detected on CR. Descriptive statistics and χ(2) tests were used for univariate analysis. A regression analysis was performed to determine characteristics predictive of a PTX on CR, and 1 variable was added to the model for every 10 positive CRs. With equal-size groups, this study has the power of 80% to detect a 10% absolute difference in single predictors of PTX on CR with 45 subjects in each group. There were 134 CT-documented PTXs included in the study. Mean age was 42, and 74% were men. For 66 (49%) patients, PTX was detected on CR (sensitivity = 50%). The CR detected 30% of small PTX, 35% of moderate PTX, and 33% of large PTX. Comparing patients with and without PTX on CR, there were no significant differences in shortness of breath or chest pain. There no relationships between PTX detected

  19. Cross-Cultural Validation of the Basic Psychological Needs in Physical Education Scale between Portugal and Brazil Samples.

    Science.gov (United States)

    Cid, Luis; Lettnin, Carla; Stobäus, Claus; Monteiro, Diogo; Davoglio, Tárcia; Moutão, João

    2016-02-19

    The main propose of this study is the cross-cultural validation of the Basic Psychological Needs in Physical Education Scale among Portugal and Brazil samples, through the study of measurement model invariance. Participated in this study, two independent samples, one with 616 Portuguese students, of the 2nd and 3rd basic grade of public school, aged between 9 and 18 years old and another with 450 Brazilian students, from 1st, 2nd and 3rd middle grade of public and private school, aged between 14 and 18 years old. The results support the suitability of the model (three factors, each one with four items), showing an adequate fit to the data in each sample (Portugal: χ2 = 203.8, p = .001, df = 51, SRMR = .062, NNFI = .926, CFI = .943, RMSEA = .070, RMSEA 90% IC = .060-.080; Brazil: χ2 = 173.7, p = .001, df = 51, SRMR = .052, NNFI = .940, CFI = .954, RMSEA = .073, RMSEA 90% IC = .061-.085), as well valid cross-cultural invariance among Portuguese e Brazilian samples (∆CFI ≤ .01). Those findings allow us to conclude that scale can be used to measure the basic psychological needs in physical education in Portugal and in Brazil.

  20. THE EUROPEAN UNION EXPOSED TO THE RISK OF THE SOVEREIGN DEBT CRISIS. CASE STUDY: SPAIN AND PORTUGAL

    Directory of Open Access Journals (Sweden)

    Ioana-Iulica, MIHAI

    2013-12-01

    Full Text Available The global economic crisis, intensely debated, started almost six years ago, subjected the EU to new resistance tests because of the macroeconomic imbalances in the Euro Zone, generated by the increase of sovereign debts, especially in the PIIGS countries (Portugal, Ireland, Italy, Greece, Spain. The situation has degenerated because of the lack of legal leverages through which the member countries should be forced to correct the fiscal imbalances and to meet the macroeconomic convergence criteria imposed. The Treaty on Fiscal Governance in the EU, signed on 2 March 2012, appears to be the key to the macroeconomic recovery in the Euro Zone, due to the more severe budgetary discipline it imposes. This paper, by means of deductive analysis and causal explanations, outlines the current economic situation of the Euro Zone, under the impact of the member countries’ sovereign debt crisis, focusing on Spain and Portugal. In addition to reliable statistics, the paper also presents the EU’s economic recovery strategy that anticipates its future. Unfortunately, the perspective of the Euro Zone is still in a fairly high degree of uncertainty, strongly influenced by the economic development of the member countries and by solving the problems they face. Spain and Portugal are the actual example.

  1. Safety of radioactive sources in Portugal

    International Nuclear Information System (INIS)

    Ferro de Carvalho, A.

    2001-01-01

    The safety of radioactive sealed sources is assured in Portugal through a control system with a main goal of prevention of lost of control and inappropriate waste. The legal tools of the regulatory system are: authorization to use, keep, transfer or transport; a deposit of money as a guarantee; civil liability insurance; periodical information. The competent authority shall keep a national inventory of sealed sources. About 50% of the new sources authorized in 1999 were to be used in medical brachytherapy and industrial radiography. The radionuclide Ir-192 contributed with 99.6 % to the total amount of activity. The control system implemented in the country appears to be effective for activities over some GBq but quite ineffective for lower activities. It is supposed that the law will be revised in the near future to increase the effectiveness of the sealed source control system. (author)

  2. Opportunities for teaching and studying medicine in medieval Portugal before the foundation of the University of Lisbon (1290).

    Science.gov (United States)

    McCleery, I

    2000-01-01

    This paper discusses where Portuguese physicians studied medicine. The careers of two thirteenth-century physicians, Petrus Hispanus and Giles of Santarem, indicate that the Portuguese travelled abroad to study in Montpellier or Paris. But it is also possible that there were opportunities for study in Portugal itself. Particularly significant in this respect is the tradition of medical teaching associated with the Augustinian house of Santa Cruz in Coimbra and the reference to medical texts found in Coimbra archives. From these sources it can be shown that there was a suitable environment for medical study in medieval Portugal, encouraging able students to further their medical interests elsewhere.

  3. Los Militares en la Revolución y en la Transición a la Democracia en Portugal

    OpenAIRE

    Rezola, Maria Inácia

    2016-01-01

    En la madrugada del día 25 de abril de 1974, un grupo de oficiales de las Fuerzas Armadas Portuguesas puso en marcha un golpe militar que, en menos de 24 horas, deponía a la más antigua y larga dictadura europea contemporánea. La transición hacia la democracia en Portugal acabará revelándose original pero agitada. Mientras en otros países, como España, la transición se hizo de forma gradual y pactada, en Portugal se asistió a una ruptura del sistema y al desencadenamiento de un proceso rev...

  4. THE TOURISM POTENTIAL OF NORTHERN PORTUGAL AND ITS RELEVANCE FOR A REGIONAL BRANDING STRATEGY

    NARCIS (Netherlands)

    Oliveira, Eduardo

    2014-01-01

    The purpose of this article is to explore a potential regional branding strategy for the northern part of Portugal, emphasizing the regional tourism potential. Furthermore, it aims to clarify the answers of the following research questions: i) is tourism a strategic domain with the potential to

  5. Sexualidades politizadas: ativismo nas áreas da AIDS e da orientação sexual em Portugal Politicized sexualities: AIDS activism and sexual orientation in Portugal

    Directory of Open Access Journals (Sweden)

    Ana Cristina Santos

    2002-06-01

    Full Text Available O presente artigo analisa a forma como o Estado português e a sociedade civil têm tratado a questão da AIDS, enfatizando o envolvimento da comunidade lésbica, gay, bissexual e transexual (LGBT no combate ao vírus. Começamos pela descrição da situação dos membros dessa comunidade em Portugal ao longo da década de 90, período da emergência e consolidação do movimento LGBT português. Num segundo momento, caracterizamos a evolução do complexo HIV/AIDS no citado país, analisando a relação entre a sociedade civil e as questões relacionadas com a sexualidade em geral, por um lado, e a situação da epidemia, por outro, considerando fatos, iniciativas estatais e associações existentes. Num terceiro momento, consagramos especial atenção ao papel desempenhado pelas associações LGBT na luta contra o HIV/AIDS. Finalmente, refletimos acerca do futuro da luta contra a epidemia e a discriminação no século XXI, tendo em conta os desenvolvimentos verificados no País e as linhas orientadoras da política de combate à AIDS adotadas por organismos internacionais.This article analyzes how both the Portuguese state and civil society have addressed the AIDS issue, focusing on participation by the lesbian, gay, bisexual, and transsexual community (LGBT in the struggle against AIDS. The article begins by describing the situation of LGBT individuals in Portugal during the 1990s, when the Portuguese LGBT movement emerged and grew, and then characterizes the evolution of HIV/AIDS in Portugal, analyzing the relationship between civil society and sexuality in general and the situation of the epidemic in the country in particular, considering key facts, nongovernmental organizations, and state initiatives. Special attention is given to the role played by LGBT organizations in the struggle against HIV. Finally, the article reflects on the future of the struggle against both AIDS and discrimination in the 21st century, considering recent events

  6. A survey of entomopathogenic nematode species in continental Portugal.

    Science.gov (United States)

    Valadas, V; Laranjo, M; Mota, M; Oliveira, S

    2014-09-01

    Entomopathogenic nematodes (EPN) are lethal parasites of insects, used as biocontrol agents. The objectives of this work were to survey the presence of EPN in continental Portugal and to characterize the different species. Of the 791 soil samples collected throughout continental Portugal, 53 were positive for EPN. Steinernema feltiae and Heterorhabditis bacteriophora were the two most abundant species. Analysis of EPN geographical distribution revealed an association between nematode species and vegetation type. Heterorhabditis bacteriophora was mostly found in the Alentejo region while S. feltiae was present in land occupied by agriculture with natural vegetation, broadleaved forest, mixed forest and transitional woodland-shrub, agro-forestry areas, complex cultivated patterns and non-irrigated arable land. Although no clear association was found between species and soil type, S. feltiae was typically recovered from cambisols and H. bacteriophora was more abundant in lithosols. Sequencing of the internal transcribed spacer (ITS) region indicated that S. feltiae was the most abundant species, followed by H. bacteriophora. Steinernema intermedium and S. kraussei were each isolated from one site and Steinernema sp. from two sites. Phylogenetic analyses of ITS, D2D3 expansion region of the 28S rRNA gene, as well as mitochondrial cytochrome c oxidase subunit I (COXI) and cytochrome b (cytb) genes, was performed to evaluate the genetic diversity of S. feltiae and H. bacteriophora. No significant genetic diversity was found among H. bacteriophora isolates. However, COXI seems to be the best marker to study genetic diversity of S. feltiae. This survey contributes to the understanding of EPN distribution in Europe.

  7. Essai de Phytoclimatologie dynamique dans le nord du Portugal, et réflexion sur les climats mediterranéens portugais

    Directory of Open Access Journals (Sweden)

    Ana Isabel D. Correia

    1996-05-01

    Full Text Available A STUDY IN DYNAMIC PHYTOCLIMATOLOGY IN THE NORTH OF PORTUGAL AND THE QUESTION OF MEDITERRANEAN CLIMATES IN PORTUGAL - The climate-vegetation relation in the north of Portugal is studied in a new way. The dynamic continuity of the climate is revealed by the existence of botanical "continuums". The vegetation sampling was made along a continous NW-SE line transect, 185 km long, parallel to the strongest pluviometric gradient. Multivariate analysis and some of the applications of the information theory were used in the floristic study. In the climate study the spatial patterns of daily values of precipitation were analysed for a period of three years. This description was also done by means of multivariate analysis, including CCA for the aerological explanation. A "threshold of hydric satisfaction", around 1400mm of mean annual rainfall seems to determine the existence of an Atlantic vegetation, between the Alvão and Falperra mountains and the Ocean. This vegetation is homogeneous because it does not respond to the udometric variations above this level. To the east, the Atlantic vegetation rapidly dissapears. The comparison between daily precipitation regimes in the different stations and the dynamic interpretation of the differences bring some light to the discussion about the climate in the NW of the Iberian Peninsula: is it an Atlantic or a Mediterranean climate? In the maritime coast of Portugal these two influences mingle, as opposed to the sheltered interior provinces.

  8. The demise of multidrug-resistant HIV-1: the national time trend in Portugal.

    Science.gov (United States)

    Vercauteren, Jurgen; Theys, Kristof; Carvalho, Ana Patricia; Valadas, Emília; Duque, Luis Miguel; Teófilo, Eugénio; Faria, Telo; Faria, Domitília; Vera, José; Aguas, Maria João; Peres, Susana; Mansinho, Kamal; Vandamme, Anne-Mieke; Camacho, Ricardo Jorge

    2013-04-01

    Despite a decreasing mortality and morbidity in treated HIV-1 patients, highly active antiretroviral treatment (HAART) can still fail due to the development of drug resistance. Especially, multidrug-resistant viruses pose a threat to efficient therapy. We studied the changing prevalence of multidrug resistance (MDR) over time in a cohort of HIV-1-infected patients in Portugal. We used data of 8065 HIV-1-infected patients followed from July 2001 up to April 2012 in 22 hospitals located in Portugal. MDR at a specific date of sampling was defined as no more than one fully active drug (excluding integrase and entry inhibitors) at that time authorized by the Portuguese National Authority of Medicines and Health Products (INFARMED), as interpreted with the Rega algorithm version 8.0.2. A generalized linear mixed model was used to study the time trend of the prevalence of MDR. We observed a statistically significant decrease in the prevalence of MDR over the last decade, from 6.9% (95% CI: 5.7-8.4) in 2001-03, 6.0% (95% CI: 4.9-7.2) in 2003-05, 3.7% (95% CI: 2.8-4.8) in 2005-07 and 1.6% (95% CI: 1.1-2.2) in 2007-09 down to 0.6% (95% CI: 0.3-0.9) in 2009-12 [OR=0.80 (95% CI: 0.75-0.86); P<0.001]. In July 2011 the last new case of MDR was seen. The prevalence of multidrug-resistant HIV-1 is decreasing over time in Portugal, reflecting the increasing efficiency of HAART and the availability of new drugs. Therefore, in designing a new drug, safety and practical aspects, e.g. less toxicity and ease of use, may need more attention than focusing mainly on efficacy against resistant strains.

  9. THE RISKS OF A TOO QUICK EURO ADOPTION BY THE EU MEMBER STATES. THE CASE OF PORTUGAL

    Directory of Open Access Journals (Sweden)

    Cristian Stefan Ovidiu

    2011-12-01

    Full Text Available In this article we present the risks faced by the new countries that have joined the European Union, and which also desire to adopt the euro currency as quickly as possible. We will analyze the existing literature regarding the ways these risks manifest themselves, depending on the economic conditions present in these countries. The risks are mostly caused by an incomplete fulfillment of the optimum currency area conditions, especially the ones regarding the synchronization of the business cycles, the existence of mitigation mechanisms in the case of asymmetric shocks, and to a lesser extent, the insufficient flexibility of the European labor markets. In addition, because there are different economic conditions between the countries that plan on introducing the euro currency and the ones that already had, mostly related to a lower economic development and lower prices, there are specific risks that affect the former countries. Moreover, the benefits of entering the EMU greater monetary stability, reduced transaction costs, lower exchange rate volatility and a decrease of the interest rates can in some specific cases become also costs. In order to quantify all these elements, we have constructed a case study of Portugal, which has entered the EMU in the first wave. We have determined that Portugal's experience after the euro introduction was a negative one, when compared with the previous period, because the convergence process did not actually happened, as expected. Not only that, but the economic differences between Portugal and the other EMU countries deepened, and the country's fiscal situation also deteriorated badly in all these years, up to the point where Portugal was forced to ask for external help. The case of Portugal is very important for the countries that are eager to adopt the common currency without first achieving a sustainable economic development, through increasing labor productivity and exports. It shows that fulfilling the

  10. Biotic and abiotic interactions in temporary summer pools of southern Portugal

    OpenAIRE

    Rosado, Joana; Morais, Manuela; Guilherme, Pedro; Ilheu, Maria

    2012-01-01

    In the south of Portugal, the summer season is characterized by reduced precipitation and high air temperatures, which causes the disruption of surface flow and subsequent formation of disconnect pools that may dry out entirely. During this dry period, there is a natural decrease of water quality standards due to the lack of water, leaving temporary rivers very vulnerable. Nevertheless, the remaining pools and surroundings become important in the survival of biological communities. Aquatic...

  11. Deterministic approach for multiple-source tsunami hazard assessment for Sines, Portugal

    OpenAIRE

    Wronna, M.; Omira, R.; Baptista, M. A.

    2015-01-01

    In this paper, we present a deterministic approach to tsunami hazard assessment for the city and harbour of Sines, Portugal, one of the test sites of project ASTARTE (Assessment, STrategy And Risk Reduction for Tsunamis in Europe). Sines has one of the most important deep-water ports, which has oil-bearing, petrochemical, liquid-bulk, coal, and container terminals. The port and its industrial infrastructures face the ocean southwest towards the main seismogenic sources. This...

  12. Os cursos de Ciência da Informação no Brasil e em Portugal: perspectivas diacrônicas Cursos de Ciencia de la Informacion en Brasil y en Portugal: perspectivas diacrónicas

    Directory of Open Access Journals (Sweden)

    Terezinha Batista de Souza

    2009-10-01

    Full Text Available Apresenta uma breve retrospectiva histórica da Ciência da Informação (CI no Brasil e em Portugal. No Brasil a C.I foi introduzida na década de 70 com a implementação do Mestrado, no Instituto Brasileiro de Bibliografia e Documentação (IBBD e em Portugal surgiu a partir dos cursos de pós-graduação em Ciências Documentais que evoluíram no sentido da adoção do termo Ciência da Informação, tendo em vista a implementação, em 2001, num esforço conjunto entre a Faculdade de Engenharia e a Faculdade de Letras da primeira Licenciatura em CI. Neste sentido mostra as as diferenças e semelhanças, bem como o quadro atual da CI nos dois países.

  13. Turismo médico em Portugal : análise de viabilidade do desenvolvimento de um operador turístico

    OpenAIRE

    Pereira, Joana Santos Brilha, 1990-; Antão, Mário Alexandre Guerreiro, 1965-

    2016-01-01

    Lusíada. Economia & Empresa. - ISSN 1645-6750. - S. 2, n. 20 (2016). - p. 61-79 Este estudo visa um dos sectores de atividade económica mais importantes para Portugal; a indústria turística. Propõe incidir a sua análise sobre o conceito de Turismo Médico, através da análise da viabilidade da criação de um operador turístico especializado, não esquecendo a importância dos demais factores para o aparecimento e desenvolvimento do Turismo Médico em Portugal. Pretende-se compreender de que f...

  14. Report on the progress of work in Portugal [Processing of Low-Grade Uranium Ores]; Rapport sur l'etat d'avancement des travaux au Portugal

    Energy Technology Data Exchange (ETDEWEB)

    Carreira Pich, H [Junta de Energia Nuclear, Laboratorio de Fisica e Engenharia Nucleares, Sacavem (Portugal)

    1967-06-15

    The purpose of the principal studies until now in Portugal were the development of two types of treatment of the uranium minerals: - Traditional leaching by agitation of the ore milled in a finely sulphuric acid solution; - Leaching of the type 'heap leaching' in which the ore is hard crushed, and then sprinkles is crammed with sulphuric acid solution. Leaching tests were performed traditionally with samples of available Portuguese minerals. In most cases, the dissolution of uranium is easy and low consumption of acid. Efforts were oriented in the direction of a leaching type 'heap leaching'.

  15. High speed in Portugal - metamorphosis from planning construction measures to a national railway concept; Hochgeschwindigkeit in Portugal - von der Bauplanung zu einem nationalen Eisenbahnkonzept

    Energy Technology Data Exchange (ETDEWEB)

    Stohler, Werner [Beratungfirma SMA und Partner AG, Zuerich (Switzerland)

    2010-03-15

    Portugal is planning the construction of two high-speed railway lines (using the UIC gauge of 1435 mm) between Lisbon and Madrid and between Lisbon and Porto. Integration with the country's existing Iberian-gauge network will be achieved in some places by laying three-rail tracks and in other places by running trains with adjustable wheel gauges. The adaptations to the legacy network triggered by the plants for the high-speed lines include, inter alia, a rearrangement of the networks of the regional-express services in and around Lisbon and Porto. (orig.)

  16. REDES COMUNITARIAS DE BANDA ANCHA: UNA CONTRIBUCIÓN PARA EL DESARROLLO REGIONAL EN PORTUGAL COMMUNITY NETWORKS: A CONTRIBUTE FOR REGIONAL DEVELOPMENT IN PORTUGAL Redes comunitárias de banda larga: um contributo para o desenvolvimento regional em Portugal

    Directory of Open Access Journals (Sweden)

    Flávio Paulo Jorge Nunes

    2010-12-01

    Full Text Available El acceso a Internet por banda ancha constituye una potencialidad cada vez más relevante en el dominio del desarrollo regional, con todo la privatización y la liberalización del sector de las telecomunicaciones y la mera aplicación de las reglas del mercado no han conseguido asegurar una repartición geográfica equitativa del acceso a la banda ancha. Ante la constatación de esta tendencia se ha requerido financiación pública para la creación de las infraestructuras necesarias para generalizar el acceso a esta red, sobre todo en las áreas rurales menos pobladas. Este estudio tiene como objetivo evaluar la respuesta dada en Portugal para complementar la acción de las operadoras privadas de telecomunicaciones, con la creación de redes comunitarias de banda ancha. Actualmente está en curso la implementación de cuatro proyectos de redes comunitarias en Portugal, que pretenden viabilizar el acceso a aplicaciones telemáticas más innovadoras, las cuales constituyen hoy en día una condición necesaria para el éxito de muchos de los proyectos más innovadores de desarrollo regional y local.Broadband Internet access offers several potential benefits as a regional and local development tool, however it is nowadays commonly accepted that privatisation and pro-competitive policies are not enough to ensure a reasonable geographical equality as regards broadband access. Therefore public policies are more and more required in order to achieve a greater infrastructural equity and a widespread use of advanced telecommunications services in less-populated markets (rural areas. In several countries Governments are investing public funds in community-based broadband solutions, as an alternative method for the provision of local broadband services. This study will evaluate how the Portuguese government is trying to complement the action of Internet Service Providers (private operators with public policies for under-served areas (“notspots”, in

  17. The Electronic Control of the Employer in Portugal

    Directory of Open Access Journals (Sweden)

    Teresa Coelho Moreira

    2016-02-01

    Full Text Available The way the work is made has been suffering in the last years countless changes related with the huge increase and development of the use of new information and communication technologies in the work relationship. The theme of privacy and surveillance of the employer have been turning in a matter of considerable interest and surrounded of great controversy in the last years all around the world and Portugal is no exception.The technological innovation allows, through several instruments as the use of video surveillance, GPS, RFID, control of electronic communications, control of online social networks or the internet, the continuous surveillance and monitoring of the workers and new questions arise in the horizon. These new forms of control constitute powerful means of surveillance and of memorization, but also of analysis and of interference in the people’ privacy, and one of the major challenges put today is the regulation of this new forms of control in the workplace because the advancement of modern technology has made it possible to collect and store information on a seemingly limitless scale, while also facilitating access to it. The question that arises before the use of this technology is to know what limits should be established. And the answer is related, it seems, with the principles of data protection, mainly, in Portugal, articles 20, 21 and 22 of Portuguese Labour Code and also the Portuguese Data Protection Act, Law number 67/98, from 26th October, and, most of all, the legitimate principle, the proportionality principle and the transparency principle.This as led to a new form of control much more intrusive and that controls almost everything even the way the worker thinks.

  18. GIS-Based Suitability Model for Assessment of Forest Biomass Energy Potential in a Region of Portugal

    Science.gov (United States)

    Quinta-Nova, Luis; Fernandez, Paulo; Pedro, Nuno

    2017-12-01

    This work focuses on developed a decision support system based on multicriteria spatial analysis to assess the potential for generation of biomass residues from forestry sources in a region of Portugal (Beira Baixa). A set of environmental, economic and social criteria was defined, evaluated and weighted in the context of Saaty’s analytic hierarchies. The best alternatives were obtained after applying Analytic Hierarchy Process (AHP). The model was applied to the central region of Portugal where forest and agriculture are the most representative land uses. Finally, sensitivity analysis of the set of factors and their associated weights was performed to test the robustness of the model. The proposed evaluation model provides a valuable reference for decision makers in establishing a standardized means of selecting the optimal location for new biomass plants.

  19. The Electoral Geography of the 2016 Presidential Election in Portugal

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    Giorgian-Ionuţ GUŢOIU

    2016-07-01

    Full Text Available Portugal elected a new president in January, this year. While the campaign was rather atypical, with a majority of independent candidates and a low involvement of the parties, we employ here an analysis of the election’s electoral geography, in order to identify if the geographical partisan delimitations influenced the electoral outcome. At this election a clear political geographical divide existed between the urban North and the rural South. Our findings suggest that the geographical distribution of the votes follows the candidates’ ideological identity.

  20. Para um Programa de Estudo do Neolítico em Portugal

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    Victor dos Santos GONÇALVES

    2009-10-01

    Full Text Available RESUMEN: El autor presenta, en líneas generales, los principales problemas de análisis del Neolítico en Portugal. Problemas que sólo en algunos casos son exclusivos del territorio portugués, ya que la mayor parte de ellos están ligados a la compleja evolución global del Neolítico en el Mediterráneo occidental. A continuación va a referirse a las propias dificultades intrínsecas para la definición de un concepto de Neolítico, e indica la escasez de información que todavía hoy existe a propósito del Neolítico portugués. Cita como ejemplo de las distorsiones provocadas por esta situación el caso de la cerámica cardial, escasa en el Neolítico antiguo portugués, donde abunda la cerámica incisa e impresa no cardial. En lo que se refiere al Neolítico antiguo, señala las principales estaciones encontradas hasta hoy en Portugal y alude más ampliamente a propósito de una, inédita el abrigo «das Bocas» (Rio Maior. A continuación, analiza las perspectivas con que se tendrá que abordar el fenómeno megalítico, planteando diversos problemas y enumerando las posibles acepciones para la palabra. Igualmente se refiere a la relación entre las inhumaciones en tres grutas localizadas en la región de Alcanena (la «Gruta dos Carrascos», la «Lapa da Galinha» y la «Gruta da Marmota» y una de las fases del megalitismo coincidente con el Neolítico medio. Sin embargo, como subraya el autor, únicamente un trabajo pluridisciplinar y de equipo podrá contribuir para obtener soluciones positivas a este problema.ABSTRACT: The Author presents an outline of the mam problems of the analysis of the Neolithic in Portugal. Problems that only in certain cases are exclusively found in Portuguese territory, since most of them are connected with the global evolution of the Neolithic in the Western Mediterranean. He refers the difficulties to found a definition for the concept of Neolithic and he points out the shortage of information that still

  1. MODERNIZATION OF GENEOTIPING OF STRAINS B. PERTUSSIS

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    G. A. Ivashinnikova

    2013-01-01

    Full Text Available The new rapid molecular genotyping method was developed for studying the structure of ptxP promoter of pertussis toxin. Method is based on PCR-RFLP analysis, which allows studying the specific restriction profiles of the B. pertussis strains and allows differentiation of the strains with the ptxP structural particularities. The developed method for genotyping of strains of B. pertussis can be hhelpful when monitoring strains of the causative agent of whooping cough in system of an epidemiological surveillance over pertussis infections, allowing observation over circulating population of B.pertussis, revealing strains of the causative agent of whooping cough with high production of pertussis toxin and to watch their distribution.

  2. Incidence and prevalence of hypercholesterolemia in Portugal: a systematic review. Part III.

    Science.gov (United States)

    Costa, João; Borges, Margarida; Oliveira, Eduardo; Gouveia, Miguel; Carneiro, António Vaz

    2003-06-01

    Over 50% of the mortality and disability caused by ischemic heart disease and stroke could be avoided by controlling individual risk factors (hypertension, hypercholesterolemia, smoking and obesity). The ignorance of the extent and impact of hypercholesterolemia (HC) in Portugal prompted us to undertake this systematic review of the prevalence and incidence of hyperlipidemia in Portugal, based exclusively on work published nationally. We included every study published in the country that could provide data on the prevalence or incidence of hypercholesterolemia. The search strategy included an electronic search of national and international biomedical databases (Medline, Index Revistas Médicas Portuguesas, the Portuguese Directorate-General for Health and the Portuguese National School of Public Health), screening of reference lists from the individual studies, and personal contacts with institutions, groups and authors (such as the Portuguese Foundation of Cardiology). The data--recorded in electronic format--was collected independently by two of the authors (JC and MB), with consensus achieved with a third (AVC) when there were differences in the study coding. We could only identify one paper on the incidence of HC in Portugal, which gave an incidence of 559 new cases per 100,000 inhabitants, increasing with age up to 54 years for men and 64 years for women. There was a higher incidence in men than in women up to the age of 54, but at more advanced ages this relationship was reversed. Prevalence studies on HC included 53,445 individuals overall, with sample size lower than 1000 in most of the individual studies. The most frequently used criterion for HC was > 200 mg/dL, with the mean level being higher in most studies. We calculated the mean prevalence for several cut-off points (> or = 190 mg/dL: 63.8%; > or = 200 mg/dL: 56.7%; > or = 240 mg/dL; 31.7%; > or 250 mg/d; 21%). Due to the heterogeneity of the data, these results are to be interpreted with caution

  3. Post-fire diversity and abundance in pine and eucalipt stands in Portugal: effects of biogeography, topography, forest type and post-fire management

    OpenAIRE

    Maia, P.; Keizer, J.; Vasques, A.; Abrantes, N.; Roxo, L.; Fernandes, P.; Ferreira, A.; Moreira, F.

    2014-01-01

    This study concerned the mid-term regeneration of the woody understory vegetation of pure and mixed stands of Pinus pinaster Ait. and Eucalyptus globulus Labill. in northern and central Portugal following wildfires in 2005 and 2006. Pine and eucalypt stands are the most widespread and most fire-prone forest types in Portugal. The main aim was to investigate the importance of biogeography, topography, forest type and post-fire management operations in explaining the patterns in shr...

  4. ESSAY ON THE EFFECTIVENESS OF THE COLLECTIVE PROTECTION IN PORTUGAL

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    Luciano Picoli Gagno

    2017-08-01

    Full Text Available This essay aims to examine certain aspects concerning collective judicial process by the light of some Portuguese cases, having as base the collective judicial protection understood as a fundamental right. With regard to the employed research method, the approach is the qualitative one, while the method is the deductive and the technique is the bibliographic e jurisprudential research. The theoretical framework is based on the doctrine and theory of some of the cited authors during the research. Among them are Robert Alexy, Mauro Cappelletti and Bryant Garth. In addition, this paper is divided into three sections: the first one is a brief study on access to justice clarified as a fundamental right of the citizen. In the second section a parallel is made with the first one, but the collective judicial protection is therefore seen as a fundamental right. In the third and last section we have the analysis of four cases of two superior courts of Portugal, being them the Supreme Court of Justice (STJ and the Supreme Administrative Court (STA, in order to understand the collective process in Portugal and to see which points that can offer a contribution for the brazilian collective procedural technic. As a result, it is found that collective judicial protection is inevitable and immanent for a substantial vision of the fundamental right of access to justice, understood like a orders of optimization, that may his realization in the biggest measure is possible

  5. A Novel Paclitaxel Microemulsion Containing a Reduced Amount of Cremophor EL: Pharmacokinetics, Biodistribution, and In Vivo Antitumor Efficacy and Safety

    Science.gov (United States)

    Wang, Ying; Wu, Ke-Chun; Zhao, Bing-Xiang; Zhao, Xin; Wang, Xin; Chen, Su; Nie, Shu-Fang; Pan, Wei-San; Zhang, Xuan; Zhang, Qiang

    2011-01-01

    The purpose of this study was to prepare a novel paclitaxel (PTX) microemulsion containing a reduced amount of Cremophor EL (CrEL) which had similar pharmacokinetics and antitumor efficacy as the commercially available PTX injection, but a significantly reduced allergic effect due to the CrEL. The pharmacokinetics, biodistribution, in vivo antitumor activity and safety of PTX microemulsion was evaluated. The results of pharmacokinetic and distribution properties of PTX in the microemulsion were similar to those of the PTX injection. The antitumor efficacy of the PTX microemulsion in OVCRA-3 and A 549 tumor-bearing animals was similar to that of PTX injection. The PTX microemulsion did not cause haemolysis, erythrocyte agglutination or simulative reaction. The incidence and degree of allergic reactions exhibited by the PTX microemulsion group, with or without premedication, were significantly lower than those in the PTX injection group (P microemulsion had similar pharmacokinetics and anti-tumor efficacy to the PTX injection, but a significantly reduced allergic effect due to CrEL, indicating that the PTX microemulsion overcomes the disadvantages of the conventional PTX injection and is one way of avoiding the limitations of current injection product while providing suitable therapeutic efficacy. PMID:21331356

  6. Synthesis, characterization, and biological evaluation of poly(L-γ-glutamyl-glutamine-paclitaxel nanoconjugate

    Directory of Open Access Journals (Sweden)

    Sang Van

    2010-10-01

    Full Text Available Sang Van1, Sanjib K Das1, Xinghe Wang1, Zhongling Feng1, Yi Jin1, Zheng Hou1, Fu Chen1, Annie Pham1, Nan Jiang1, Stephen B Howell2, Lei Yu11Nitto Denko Technical Corporation, Oceanside, CA, USA; 2Moores Cancer Center, University of California, La Jolla, San Diego, CA, USAAbstract: The purpose of this study was to develop a novel, highly water-soluble poly(L-γ-glutamyl-glutamine-paclitaxel nanoconjugate (PGG-PTX that would improve the therapeutic index of paclitaxel (PTX. PGG-PTX is a modification of poly(L-glutamic acid-paclitaxel conjugate (PGA-PTX in which an additional glutamic acid has been added to each glutamic side chain in the polymer. PGG-PTX has higher water-solubility and faster dissolution than PGA-PTX. Unlike PGA-PTX, PGG-PTX self-assembles into nanoparticles, whose size remains in the range of 12–15 nm over the concentration range from 25 to 2,000 µg/mL in saline. Its critical micellar concentration in saline was found to be ~25 µg/mL. The potency of PGG-PTX when tested in vitro against the human lung cancer H460 cell line was comparable to other known polymer-PTX conjugates. However, PGG-PTX possesses lower toxicity compared with PGA-PTX in mice. The maximum tolerated dose of PGG-PTX was found to be 350 mg PTX/kg, which is 2.2-fold higher than the maximum tolerated dose of 160 mg PTX/kg reported for the PGA-PTX. This result indicates that PGG-PTX was substantially less toxic in vivo than PGA-PTX.Keywords: nanoconjugates, poly(L-glutamic acid, poly(L-γ-glutamyl-glutamine-paclitaxel, nanoparticles, anticancer

  7. Experiments in Popular Education in Portugal, 1974-1976. Education Studies and Documents, No. 29.

    Science.gov (United States)

    Melo, Alberto; Benavente, Ana

    The first in a series of studies of lifelong learning, this paper discusses educational activities undertaken in Portugal after the fall of the dictatorship in 1974 and through 1976. Intended for educational planners and for those working in popular education, the study emphasizes original strategies and experiments, particulary those encouraging…

  8. Well sediments: a medium for geochemical prospecting, an example from the Nisa region, Portugal

    NARCIS (Netherlands)

    Vriend, S.P.; Dekkers, M.J.; Janssen, M.A.; Commandeur, J.

    1991-01-01

    Vriend, S.P., Dekkers, M.J.. Janssen, M.A. and Commandeur, J., 1991. Well sediments: a medium for geochemical prospecting, an example from the Nisa region. Portugal. In: A.W. Rose and P.M. Taufen I Editors). Geochemical Exploration ! 989. J. Geochem. Expior., 4 ! : ! 5 I- 167. Tile potential of

  9. Subjective social status and intergroup attitudes among ethnic majority and minority children in Portugal

    NARCIS (Netherlands)

    Feddes, A.R.; Monteiro, M.B.; Justo, M.G.

    2014-01-01

    A measure of subjective social status (SSS) was examined among high (White), and low (Black and Roma) ethnic status children in Portugal within a developmental design including 6-8-year-old and 9-12-year-old children. White children favoured their ingroup over the Black and Roma out-groups on the

  10. España y Portugal durante la Segunda Guerra Mundial

    OpenAIRE

    Sacristán Lucas, Esther; Gómez de las Heras Hernández, María Soledad

    1989-01-01

    Cuando las relaciones internacionales entran en franco deterioro en el escenario europeo, el entendimiento político entre España y Portugal presentaba a la Península Ibérica como un bloque relativamente unido ante la conflagración mundial. La política exterior de estos dos Estados durante la segunda guerra mundial se enmarca dentro de unas coordenadas, que son tenidas en cuenta por los diplomáticos de ambas naciones, de los beligerantes y neutrales: la coincidencia del talante político e ideo...

  11. A Comparison of Parent and Professional Perceptions of Children with Autism Spectrum Disorder in Portugal

    Science.gov (United States)

    Reis, Helena; Pereira, Ana; Almeida, Leandro

    2017-01-01

    Improving early intervention in Portugal for children with autism spectrum disorder (ASD) requires parents and professionals to collaborate in assessing and planning intervention programmes. This article analyses parental and professional assessments of children with ASD, in the dimensions of social communication, repetitive behaviours and…

  12. Self-assembly PEGylation assists SLN-paclitaxel delivery inducing cancer cell apoptosis upon internalization.

    Science.gov (United States)

    Arranja, Alexandra; Gouveia, Luís F; Gener, Petra; Rafael, Diana F; Pereira, Carolina; Schwartz, Simó; Videira, Mafalda A

    2016-03-30

    In past years, a considerable progress has been made in the conversion of conventional chemotherapy into potent and safe nanomedicines. The ultimate goal is to improve the therapeutic window of current chemotherapeutics by reducing systemic toxicities and to deliver higher concentrations of the chemotherapeutic agents to malignant cells. In this work, we report that PEGylation of the nanocarriers increases drug intracellular bioavailability leading therefore to higher therapeutic efficacy. The surface of the already patented solid lipid nanoparticles (SLN) loaded with paclitaxel (SLN-PTX) was coated with a PEG layer (SLN-PTX_PEG) through an innovative process to provide stable and highly effective nanoparticles complying with the predefined pharmaceutical quality target product profile. We observed that PEGylation not only stabilizes the SLN, but also modulates their cellular uptake kinetics. As a consequence, the intracellular concentration of chemotherapeutics delivered by SLN-PTX_PEG increases. This leads to the increase of efficacy and thus it is expected to significantly circumvent cancer cell resistance and increase patient survival and cure. Copyright © 2016 Elsevier B.V. All rights reserved.

  13. Development of biodegradable PLGA nanoparticles surface engineered with hyaluronic acid for targeted delivery of paclitaxel to triple negative breast cancer cells.

    Science.gov (United States)

    Cerqueira, Brenda Brenner S; Lasham, Annette; Shelling, Andrew N; Al-Kassas, Raida

    2017-07-01

    This study aimed at development of poly (lactic-co-glycolic acid) (PLGA) nanoparticles embedded with paclitaxel and coated with hyaluronic acid (HA-PTX-PLGA) to actively target the drug to a triple negative breast cancer cells. Nanoparticles were successfully fabricated using a modified oil-in-water emulsion method. The effect of various formulations parameters on the physicochemical properties of the nanoparticles was investigated. SEM imaging confirmed the spherical shape and nano-scale size of the nanoparticles. A sustained drug release profile was obtained and enhanced PTX cytotoxicity was observed when MDA-MB-231 cells were incubated with the HA-PTX-PLGA formulation compared to cells incubated with the non-HA coated nanoparticles. Moreover, HA-PLGA nanoparticles exhibited improved cellular uptake, based on a possible receptor mediated endocytosis due to interaction of HA with CD44 receptors when compared to non-coated PLGA nanoparticles. The non-haemolytic potential of the nanoparticles indicated the suitability of the developed formulation for intravenous administration. Copyright © 2017 Elsevier B.V. All rights reserved.

  14. Assessing wildfire occurrence probability in Pinus pinaster Ait. stands in Portugal

    Energy Technology Data Exchange (ETDEWEB)

    Marques, S.; Garcia-Gonzalo, J.; Botequim, B.; Ricardo, A.; Borges, J. G.; Tome, M.; Oliveira, M. M.

    2012-11-01

    Maritime pine (Pinus pinaster Ait.) is an important conifer from the western Mediterranean Basin extending over 22% of the forest area in Portugal. In the last three decades nearly 4% of Maritime pine area has been burned by wildfires. Yet no wildfire occurrence probability models are available and forest and fire management planning activities are thus carried out mostly independently of each other. This paper presents research to address this gap. Specifically, it presents a model to assess wildfire occurrence probability in regular and pure Maritime pine stands in Portugal. Emphasis was in developing a model based on easily available inventory data so that it might be useful to forest managers. For that purpose, data from the last two Portuguese National Forest Inventories (NFI) and data from wildfire perimeters in the years from 1998 to 2004 and from 2006 to 2007 were used. A binary logistic regression model was build using biometrics data from the NFI. Biometric data included indicators that might be changed by operations prescribed in forest planning. Results showed that the probability of wildfire occurrence in a stand increases in stand located at steeper slopes and with high shrubs load while it decreases with precipitation and with stand basal area. These results are instrumental for assessing the impact of forest management options on wildfire probability thus helping forest managers to reduce the risk of wildfires. (Author) 57 refs.

  15. Occult Pneumothoraces in Acute Trauma Patients

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    Chad Berryman

    2012-12-01

    Full Text Available Introduction: Many traumatic pneumothoraces (PTX are not seen on initial chest radiograph (CR(occult PTX but are detected only on computed tomography (CT. Although CR remains the first toolfor detecting PTX, most trauma patients with significant thoracoabdominal injuries will receive both CTand CR. The primary objective of this study was to retrospectively determine the effectiveness of CR fordetecting PTX in trauma patients. Our hypotheses were that CR is a sensitive indicator of PTX on CT,that chest pain and shortness of breath are good predictors of PTX on CR, and that we could determineother predictors of PTX on CR.Methods: All trauma patients presenting to our Level I trauma center with a CT-diagnosed PTX over a2-year period who had both a CR and a chest CT were included. The CT reading was considered thegold standard for PTX diagnosis. Electronic medical records were searched using key words fordiagnoses, symptoms, demographics, and radiologic results. We recorded the official radiologistreadings for both CR and CT (positive or negative and the size of the PTX on CT (large, moderate,small, or tiny. The outcome variable was dichotomized based on presence or absence of PTXdetected on CR. Descriptive statistics and v2 tests were used for univariate analysis. A regressionanalysis was performed to determine characteristics predictive of a PTX on CR, and 1 variable wasadded to the model for every 10 positive CRs. With equal-size groups, this study has the power of 80%to detect a 10% absolute difference in single predictors of PTX on CR with 45 subjects in each group.Results: There were 134 CT-documented PTXs included in the study. Mean age was 42, and 74%were men. For 66 (49% patients, PTX was detected on CR (sensitivity¼50%. The CR detected 30%of small PTX, 35% of moderate PTX, and 33% of large PTX. Comparing patients with and without PTXon CR, there were no significant differences in shortness of breath or chest pain. There no

  16. Environmental contamination with Toxocara spp. eggs in public parks and playground sandpits of Greater Lisbon, Portugal.

    NARCIS (Netherlands)

    Otero, David; Alho, Ana M; Nijsse, Rolf; Roelfsema, Jeroen; Overgaauw, Paul; Madeira de Carvalho, Luís

    2018-01-01

    Toxocarosis is a zoonotic parasitic disease transmitted from companion animals to humans. Environmental contamination with Toxocara eggs is considered to be the main source of human infections. In Portugal, knowledge regarding the current situation, including density, distribution and environmental

  17. Environmental contamination with Toxocara spp. eggs in public parks and playground sandpits of Greater Lisbon, Portugal

    NARCIS (Netherlands)

    Otero, David; Alho, Ana M.; Nijsse, Rolf; Roelfsema, Jeroen; Overgaauw, Paul; Madeira de Carvalho, Luís

    2018-01-01

    Toxocarosis is a zoonotic parasitic disease transmitted from companion animals to humans. Environmental contamination with Toxocara eggs is considered to be the main source of human infections. In Portugal, knowledge regarding the current situation, including density, distribution and environmental

  18. Sexualidad juvenil y cambio social: el caso de Portugal Youth sexuality and social change: the case of Portugal

    Directory of Open Access Journals (Sweden)

    José Machado-Pais

    2003-01-01

    Full Text Available OBJETIVO: Investigar si, dentro de un marco de profundos cambios sociales, las nuevas generaciones estarán creando nuevos valores sociales. MATERIAL Y MÉTODOS: Aplicando el método de las generaciones, se utilizaron datos de una encuesta sobre valores y generaciones, hecho en 1996 a 2 012 individuos residentes en Portugal continental y representativos de la población portuguesa. Recurriendo al programa SPAD (Estadística para análisis de datos, se procedió a un análisis factorial de correspondencias múltiples en conjugación con un análisis de tipo cluster. RESULTADOS: Constatamos que las principales discontinuidades intergeneracionales se presentan en el área de las actitudes y prácticas sexuales. Comprobamos que los grupos y agregados resultantes del análisis tienen índices de sobrerrepresentación de generaciones específicas. Por ejemplo, los encuestados hedonistas se caracterizan por un elevado índice de sobrerrepresentación de jóvenes, en contraste con los inhibidos o los moralistas. CONCLUSIONES: Los jóvenes portugueses aparecen como una generación portadora de valores hedonistas y de carácter experimental en el plano de la vida sexual y amorosa. Sin embargo, se caracterizan al mismo tiempo por su vulnerabilidad a conductas de riesgo.OBJECTIVE: To investigate whether the new generations are creating new social values in the current setting of deep social change. MATERIAL AND METHODS: Using the generations method (Mannheim, a survey was conducted in 1996, among 2 012 residents of Portugal, to collect data on values and generations of the Portuguese population. The SPAD statistical analysis program was used to perform a multiple correspondence factorial analysis, in addition to a cluster-type analysis. RESULTS: The main generational gaps were found in sexual attitudes and practices. Findings showed that groups and aggregates have overrepresentation indices for specific generations, e.g., hedonistic interviewees are

  19. Novos dados sobre os Spoligotypes de estirpes do complexo Mycobacterium tuberculosis isoladas no Hospital Fernando Fonseca (Amadora-Sintra, Portugal

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    Suzana David

    2005-11-01

    Full Text Available Resumo: O presente estudo populacional, que decorreu entre 1999 e 2003, foi baseado na utilização do Spoligotyping na genotipagem de 452 isolados do complexo Mycobacterium tuberculosis de doentes com tuberculose internados no Hospital Fernando Fonseca. Spoligotypes foram identificados como shared types (ST recorrendo a uma base de dados internacional. Onze ST raros, não identificados na base de dados, acomodaram 8,4% dos isolados. Aliás, particular a Portugal poderá ser a predominância de ST identificados na base de dados mas não previamente classificados como famílias genotípicas, tais como o ST244, ST150 e ST389, representando 13,3 % do total. A identificação de isolados clínicos de M. africanum de genótipo Afri1 e de M. tuberculosis de genótipo CAS1 poderá confirmar a importação de isolados de origem africana e asiática. M. tuberculosis da família Beijing foi pela primeira vez por nós assinalado a partir de 1999. Desde então, o número de isolados provenientes do hospital passou de um para cinco, anualmente, representando actualmente 2,2%, o que a coloca em décimo lugar em prevalência. M. tuberculosis Beijing poderá corresponder a um problema emergente em Portugal devido à recente imigração proveniente da Europa Oriental e da Ásia. Outros genótipos, ST150 e ST389, mostraram um incremento, cujo significado não é claro. No entanto, as frequências relativas das famílias predominantes LAM, T1 e Haarlem mantiveram-se relativamente estáveis. O presente estudo confirma a variabilidade genética em Portugal dos isolados do complexo M. tuberculosis. Estes estudos poderão contribuir para a definição de prioridades nos programas nacionais de luta contra a tuberculose.Rev Port Pneumol 2005; XI (6: 513-531 Abstract: The present population study, from 1999 to 2003, has been based on the use of Spoligotyping in the genotyping of 452 isolates of

  20. Financial Report on the Internet in Portugal

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    Sandra Raquel Pinto Alves

    2005-03-01

    Full Text Available In the last decade, the advances in communication and information technologies dramaticallychanged the information flow and our notions of time and space. The Internet has been changingthe information policy of companies world-wide. Basically in all developed countries,companies are increasingly using the Internet to provide their financial information. Thisresearch presents an empirical study aiming to analyze the organization and informationprovided on the financial report of the 250 most profitable companies in Portugal, particularlytheir financial statements published on the Internet. After the observation and in-depth analysisof the websites of the above-mentioned companies, for the year 2002, it was concluded that 119companies (48% had a webpage on the internet. In what concerns the disclosure of financialinformation, only 51 (43% out of the 119 companies had some kind of financial informationstated on their websites.

  1. Public Attitudes towards Parties in Portugal: A Longitudinal Overview

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    Conceição Pequito Teixeira

    2011-06-01

    Full Text Available This article reviews the case of the often claimed “crisis of parties” in Portugal, and argues that such controversy rests at least in part on “ambiguous” evidence. We will try to answer two fundamental research questions: 1 What motivates popular support for political parties (or lack thereof? 2 Why does antiparty rhetoric resonate with some citizens, but not with others? The empirical data and statistical regression models used allow the following conclusion: in the eyes of Portuguese citizens, parties have become a kind of “necessary evil”, being criticized for “what they actually do” and supported for “what they are supposed to do”.

  2. Portugal and Spain entering the Common Market: Their industrial competitiveness revisited

    OpenAIRE

    Donges, Jürgen B.; Schatz, Klaus-Werner

    1985-01-01

    The purpose of this paper is to assess the overall position as well as the relative strength and weakness of the Iberian manufacturing industries within an enlarged Community. Earlier studies of the authors (Donges, Schatzf 1980; Donges et al., 1982) are up-dated and extended to cover the bilateral trade relations between Portugal and Spain. Following a recapitulation of the major trade patterns of the Iberian countries, we examine the nature of their specialization, both with regard to the E...

  3. Evaluation and quality libraries performance : a view from Portugal and Brazil

    OpenAIRE

    Melo, Luiza Baptista; Sampaio, Maria Imaculada

    2003-01-01

    The main purpose of this poster is to give a view of some projects, on evaluation and quality in libraries performances, which have been developed in Portugal and Brazil during the last ten years. Library services quality is a concept that librarians around of the world has been adopted, that is a way for assessing user needs, satisfaction, and better performance at the libraries. The two academic librarians present a brief description of some methods to obtain performance and quality measure...

  4. A paclitaxel prodrug with bifunctional folate and albumin binding moieties for both passive and active targeted cancer therapy.

    Science.gov (United States)

    Shan, Lingling; Zhuo, Xin; Zhang, Fuwu; Dai, Yunlu; Zhu, Guizhi; Yung, Bryant C; Fan, Wenpei; Zhai, Kefeng; Jacobson, Orit; Kiesewetter, Dale O; Ma, Ying; Gao, Guizhen; Chen, Xiaoyuan

    2018-01-01

    Folate receptor (FR) has proven to be a valuable target for chemotherapy using folic acid (FA) conjugates. However, FA-conjugated chemotherapeutics still have low therapeutic efficacy accompanied with side effects, resulting from complications such as short circulation half-life, limited tumor delivery, as well as high kidney accumulation. Herein, we present a novel FA-conjugated paclitaxel (PTX) prodrug which was additionally conjugated with an Evans blue (EB) derivative for albumin binding. The resulting bifunctional prodrug prolonged blood circulation, enhanced tumor accumulation, and consequently improved tumor therapeutic efficacy. Methods: Fmoc-Cys(Trt)-OH was coupled onto PTX at the 7'-OH position for further synthesis of ester prodrug FA-PTX-EB. The targeting ability was investigated using confocal microscopy and flow cytometry. The pharmacokinetics of this bifunctional compound was also studied. Meanwhile, cell viability was evaluated in normal cells and three cancer cell lines by MTT assay. In vivo therapeutic effect was tested on FR-α overexpressing MDA-MB-231 tumor model. Results: Compared with free PTX, the FA-PTX, PTX-EB and FA-PTX-EB prodrugs increased circulation half-life in mice from 2.19 to 3.82, 4.41, and 7.51 h, respectively. Pharmacokinetics studies showed that the FA-PTX-EB delivered more PTX to tumors than FA-PTX and free PTX. In vitro and in vivo studies demonstrated that FA-EB-conjugated PTX induced potent antitumor activity. Conclusion: FA-PTX-EB showed prolonged blood circulation, enhanced drug accumulation in tumors, higher therapeutic index, and lower side effects than either free PTX or monofunctional FA-PTX and EB-PTX. The results support the potential of using EB for the development of long-acting therapeutics.

  5. FORMACIÓN DEL PROFESORADO DE MÚSICA EN EUROPA MERIDIONAL: CHIPRE, GRECIA, MALTA Y PORTUGAL

    Directory of Open Access Journals (Sweden)

    Juan José Carmona Fernández

    2010-01-01

    Full Text Available El presente artículo informa y reflexiona sobre los planes de estudios de formación del profesorado de música en países de Europa Septentrional: Chipre, Grecia, Malta y Portugal. La metodología de análisis utilizada es común para todos los países estudiados, correspondientes al Proyecto ALFA al que se hace referencia en el editorial de este monográfico. En Chipre hablaremos sobre tres universidades con planes de estudio musicales; en Grecia distinguiremos cuatro tipos de docentes dependiendo del nivel educativo en el que impartan docencia (Infantil, Primaria y Secundaria; en tercer lugar hablaremos sobre las peculiaridades del sistema de la universidad de Malta; se procederá al análisis de Portugal donde contamos con un número mayor de universidades; y, por último, aportaremos nuestra reflexión sobre los planes de estudios analizados y sus implicaciones para la formación del profesorado de música.

  6. ‘Holistic Mothers’ or ‘Bad Mothers’? Challenging Biomedical Models of the Body in Portugal

    Directory of Open Access Journals (Sweden)

    Anna Fedele

    2016-06-01

    Full Text Available This paper is based on early fieldwork findings on ‘holistic mothering’ in contemporary Portugal. I use holistic mothering as an umbrella term to cover different mothering choices, which are rooted in the assumption that pregnancy, childbirth and early childhood are important spiritual occasions for both mother and child. Considering that little social scientific literature exists about the religious dimension of alternative mothering choices, I present here a first description of this phenomenon and offer some initial anthropological reflections, paying special attention to the influence of Goddess spirituality on holistic mothers. Drawing on Pamela Klassen’s ethnography about religion and home birth in America (2001, I argue that in Portugal holistic mothers are challenging biomedical models of the body, asking for a more woman-centred care, and contributing to the process, already widespread in certain other European countries, of ‘humanising’ pregnancy and childbirth.

  7. Cellular uptake mechanism and comparative evaluation of antineoplastic effects of paclitaxel–cholesterol lipid emulsion on triple-negative and non-triple-negative breast cancer cell lines

    Directory of Open Access Journals (Sweden)

    Ye J

    2016-08-01

    Full Text Available Jun Ye,1,2 Xuejun Xia,1,2 Wujun Dong,1,2 Huazhen Hao,1,2 Luhua Meng,1,2 Yanfang Yang,1,2 Renyun Wang,1,2 Yuanfeng Lyu,3 Yuling Liu1,2 1State Key Laboratory of Bioactive Substance and Function of Natural Medicines, 2Beijing Key Laboratory of Drug Delivery Technology and Novel Formulation, Institute of Materia Medica, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, 3School of Pharmacy, China Pharmaceutical University, Nanjing, People’s Republic of China Abstract: There is no effective clinical therapy for triple-negative breast cancers (TNBCs, which have high low-density lipoprotein (LDL requirements and express relatively high levels of LDL receptors (LDLRs on their membranes. In our previous study, a novel lipid emulsion based on a paclitaxel–cholesterol complex (PTX-CH Emul was developed, which exhibited improved safety and efficacy for the treatment of TNBC. To date, however, the cellular uptake mechanism and intracellular trafficking of PTX-CH Emul have not been investigated. In order to offer powerful proof for the therapeutic effects of PTX-CH Emul, we systematically studied the cellular uptake mechanism and intracellular trafficking of PTX-CH Emul and made a comparative evaluation of antineoplastic effects on TNBC (MDA-MB-231 and non-TNBC (MCF7 cell lines through in vitro and in vivo experiments. The in vitro antineoplastic effects and in vivo tumor-targeting efficiency of PTX-CH Emul were significantly more enhanced in MDA-MB-231-based models than those in MCF7-based models, which was associated with the more abundant expression profile of LDLR in MDA-MB-231 cells. The results of the cellular uptake mechanism indicated that PTX-CH Emul was internalized into breast cancer cells through the LDLR-mediated internalization pathway via clathrin-coated pits, localized in lysosomes, and then released into the cytoplasm, which was consistent with the internalization pathway and intracellular trafficking of native

  8. The dynamics of cork oak systems in Portugal: the role of ecological and land use factors

    NARCIS (Netherlands)

    Acácio, V.C.

    2009-01-01

    Vegetation degradation and desertification occur in many semiarid ecosystems worldwide, particularly in the Western Mediterranean Basin. A peculiar semiarid Mediterranean land use system dominates the landscape of southern Portugal where cork oak (Quercus suber) is the main tree species. This system

  9. Occupational exposure in nuclear medicine in Portugal in the 1999-2003 period

    International Nuclear Information System (INIS)

    Martins, M. B.; Alves, J. G.; Abrantes, J. N.; Roda, A. R.

    2007-01-01

    The annual doses received by the staff of nuclear medicine departments from public hospitals and private clinics and evaluated by the Individual Monitoring Service of the Radiological Protection and Nuclear Safety Dept. (DPRSN) of the Nuclear and Technological Inst. (ITN) in Portugal, in the 5 y period from 1999 to 2003, are analysed and presented in this paper. In the 1999-2003 period, ITN-DPRSN monitored on an average 462 workers from nuclear medicine departments, which represents 6% of the 8000 workers of the medical field (approximately). The medical sector represents 80-85% of all the monitored population in Portugal. The professions of the monitored workers at nuclear medicine departments were identified by the respective departments as administrative, auxiliary, medical doctor, nuclear medicine technician, nurse, pharmacist and physicist. This information was collected at the onset of the monitoring and was updated over the last 3 y. The annual whole-body doses evaluated in the period 1999-2003 were used to derive the distribution of workers by dose intervals for every profession. The respective annual average doses and annual collective doses, as well as, the total average and total collective doses for the nuclear medicine sector were also determined and are presented. Internal radiation hasn't been monitored. (authors)

  10. Molecular and histopathological detection of Hepatozoon canis in red foxes (Vulpes vulpes) from Portugal.

    Science.gov (United States)

    Cardoso, Luís; Cortes, Helder C E; Eyal, Osnat; Reis, Antónia; Lopes, Ana Patrícia; Vila-Viçosa, Maria João; Rodrigues, Paula A; Baneth, Gad

    2014-03-24

    Hepatozoon canis is a protozoan tick-borne pathogen of dogs and wild canids. Hepatozoon spp. have been reported to infect foxes in different continents and recent studies have mostly used the polymerase chain reaction (PCR) for the detection and characterization of the infecting species. Surveying red foxes (Vulpes vulpes) may contribute to better understanding the epidemiology of canine vector-borne diseases, including hepatozoonosis caused by H. canis in domestic dogs. The present study investigated the prevalence of Hepatozoon spp. by means of histopathology and molecular analysis of different tissues in red foxes from different parts of Portugal. Blood and tissues including bone marrow, heart, hind leg muscle, jejunum, kidney, liver, lung, popliteal or axillary lymph nodes, spleen and/or tongue were collected from 91 red foxes from eight districts in northern, central and southern Portugal. Tissues were formalin-fixed, paraffin-embedded, cut and stained with hematoxylin and eosin. Polymerase chain reaction (PCR) amplified a ~650 bp fragment of the 18S rRNA gene of Hepatozoon spp. and the DNA products were sequenced. Hepatozoon canis was detected in 68 out of 90 foxes (75.6%) from all the sampled areas by PCR and sequencing. Histopathology revealed H. canis meronts similar in shape to those found in dogs in the bone marrow of 11 (23.4%) and in the spleen of two (4.3%) out of 47 foxes (p = 0.007). All the 11 foxes found positive by histopathology were also positive by PCR of bone marrow and/or blood. Positivity by PCR (83.0%) was significantly higher (p Hepatozoon canis was found to be highly prevalent in red fox populations from northern, central and southern Portugal. Detection of the parasite by histopathology was significantly less sensitive than by PCR. Red foxes are a presumptive reservoir of H. canis infection for domestic dogs.

  11. Between Germanic and Latin eugenics: Portugal, 1930-1960

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    Richard Mark Cleminson

    Full Text Available Abstract This article assesses critically the participation of Portuguese eugenicists in “Latin eugenics” and traces the continuities and discontinuities with respect to this model. In particular, it focuses on a number of examples of more “Germanic” eugenics in contrast and in comparison to Latin versions of eugenics. In the former category, Eusébio Tamagnini, José Ayres de Azevedo and Leopoldina Ferreira de Paulo are considered; in the latter category, especially the work of Almerindo Lessa on “racial mixing” is considered. The conclusions suggest that we should seek diversity in both Latin and northern European eugenic models while at the same time placing Portugal within the array of possible versions of eugenics during the first half of the twentieth century.

  12. “Jesus made in Brazil”: notas sobre a transnacionalização do pentecostalismo brasileiro para Portugal (“Jesus made in Brazil”: notes on the transnationalization of Brazilian Pentecostalism to Portugal - DOI: 10.5752/P.2175-5841.2011v9n22p416

    Directory of Open Access Journals (Sweden)

    Paulo Gracino Junior

    2011-09-01

    Full Text Available O impacto de novas modalidades religiosas sobre “culturas locais” é um tema clássico das Ciências Sociais. Partindo das teses weberianas, muitos cientistas sociais analisam a adesão de crescentes contingentes populacionais ao protestantismo pentecostal no mundo não desenvolvido em sua relação positiva com o estabelecimento da modernidade capitalista. Porém, quando se trata da implantação desses movimentos religiosos em solo europeu, o que antes era uma “boa nova”, um sopro de modernidade para os corações latinos, torna-se algo ameaçador, capaz de corromper os sólidos pilares da modernidade europeia. Pensando nessas abordagens, a implantação do pentecostalismo brasileiro em Portugal torna-se curiosa, uma vez que é compreendida, por um lado, como uma corrupção da tradição católica portuguesa e, por outro, como um surto irracionalista, um entrave à europeização portuguesa. Dito isso, o objetivo desse trabalho é analisar como os atores sociais acionam esses aspectos nas diversas frentes de resistência ao crescimento pentecostal no país.Palavras-chave: Pentecostalismo; Transnacionalização; Brasil; Portugal. AbstractThe impact of new religious modalities on "local cultures" is a classic theme of Social Sciences. Building on the weberian thesis, many social scientists have examined the adhesion of the growing population contingents to Pentecostal Protestantism in the undeveloped world in its positive relationship with the establishment of capitalist modernity. However, when it comes to the deployment of these religious movements in Europe, what was once a "good new", a blow of modernity to the hearts of modern Latin, becomes something threatening, capable of corrupting the solid pillars of European modernity. Thinking about these approaches, the implementation of Brazilian Pentecostalism in Portugal becomes curious, since it is understood, first, as a corruption of the Portuguese Catholic tradition and, secondly

  13. Assessment for Learning in Norway and Portugal: The Case of Primary School Mathematics Teaching

    Science.gov (United States)

    Nortvedt, Guri A.; Santos, Leonor; Pinto, Jorge

    2016-01-01

    In this study, we aim to understand the forces driving assessment for learning (AfL) in primary school teaching. By applying a case study design, including the two cases of Norway and Portugal and using mathematics teaching as an example, available policy documents and research reports are analysed to identify the differences and similarities that…

  14. Glycaemic threshold for diabetes-specific retinopathy among individuals from Saudi Arabia, Algeria and Portugal

    DEFF Research Database (Denmark)

    Almdal, Thomas Peter; Handlos, Line Neerup; Vistisen, Dorte

    2014-01-01

    We studied the glycaemic threshold and prevalence of diabetic retinopathy in screen-detected diabetes in Saudi Arabia, Algeria and Portugal. The prevalence of diabetes-specific retinopathy started to increase at an HbA1c level of 6-6.4% and in individuals with HbA1c >7.0% the prevalence was 6.0%....

  15. Vidrios romanos de Bracara Augusta (Portugal: Análisis Arqueométrico = Roman glass from Bracara Augusta (Portugal: Archaeometric analysys

    Directory of Open Access Journals (Sweden)

    Rosario García Giménez

    2015-11-01

    Full Text Available En este trabajo se han estudiado vidrios romanos de Bracara Augusta, actualmente Braga (Portugal, a través de su composición química, analizando los constituyentes mayoritarios, minoritarios y traza mediante espectrometría de plasma-masas (ICPMS. Los resultados obtenidos han sido tratados estadísticamente, por un lado realizando diversos análisis univariantes, y por otro llevando a cabo una clasificación de las muestras mediante análisis de clasificación jerárquica y varios análisis discriminantes. Se llega a la conclusión de que, si bien todas las muestras de vidrio presentan una composición parecida en cuanto a los elementos mayoritarios, existen algunas diferencias significativas tanto en éstos como en los elementos minoritarios estudiados que permiten su clasificación. Además, mediante el análisis discriminante se establecen grupos en función de la datación de los vidrios y se pueden incluir en ellos las muestras previamente no datadas en los grupos anteriores.In this work Roman glass from Bracara Augusta, nowadays Braga (Portugal, were studied through their chemical composition, analyzing the major, minor and trace constituents using plasma-mass spectrometry (ICP-MS. The obtained data were statistically analysed, with the following statistical methodologies: (i various  univariate analyses and (ii several multivariate analyses which gave rise to a sample classification using hierarchical classification and by multiple discriminant analyses. Results concluded that, while all the glass samples showed a similar composition in terms of major components, there were some significant differences in these and in the minor components that allowed their classification. Furthermore, discriminant analysis helped to establish groups based on the dating of the glass and include undated samples in the previous stated groups.

  16. User Profiling and Knowledge Extraction For Tourism

    OpenAIRE

    Almeida, Diogo Miguel Rodrigues Soares de

    2015-01-01

    O sector do turismo é uma área francamente em crescimento em Portugal e que tem desenvolvido a sua divulgação e estratégia de marketing. Contudo, apenas se prende com indicadores de desempenho e de oferta instalada (número de quartos, hotéis, voos, estadias), deixando os indicadores estatísticos em segundo plano. De acordo com o “ Travel & tourism Competitiveness Report 2013”, do World Economic Forum, classifica Portugal em 72º lugar no que respeita à qualidade e cobertura da ...

  17. Peregrinos e viajantes no Norte de Portugal : as esmolas distribuídas pela ordem terceira franciscana de Braga aos irmãos «passageiros» (1720-1816

    Directory of Open Access Journals (Sweden)

    Juliana de Mello Moraes

    2010-01-01

    Full Text Available During the 18th century many people came to Braga as travellers or pilgrims. In this town they found several institutions, some of which helped the travellers materially and spiritually, such as the Third Order of Saint Francis. Based on this Order’s records, it was possible to draw a profile of those who sought out the secular order for help. At the same time, this information allowed us to analyze, from a quantitative and qualitative perspective, some relevant characteristics of travellers in northern Portugal during that period. Besides the specifics of those whom the brothers assisted, this paper also evaluates the management of this activity, that of the distribution of alms, by the secular Franciscans of Braga, revealing a welfare practice that is practically unknown in current historiography.

  18. Pilot monitoring study of ibuprofen in surface waters of north of Portugal

    OpenAIRE

    Paíga, Paula; Santos, Lúcia; Amorim, Célia G.; Araújo, Alberto N.; Montenegro, M. Conceição B. S. M.; Pena, Angelina; Delerue-Matos, Cristina

    2013-01-01

    Ibuprofen is amongst the most worldwide consumed pharmaceuticals. The present work presents the first data in the occurrence of ibuprofen in Portuguese surface waters, focusing in the north area of the country, which is one of the most densely populated areas of Portugal. Analysis of ibuprofen is based on pre-concentration of the analyte with solid phase extraction and subsequent determination with liquid chromatography coupled to fluorescence detection. A total of 42 ...

  19. Scenario based approach for multiple source Tsunami Hazard assessment for Sines, Portugal

    OpenAIRE

    M. Wronna; R. Omira; M. A. Baptista

    2015-01-01

    In this paper, we present a scenario-based approach for tsunami hazard assessment for the city and harbour of Sines – Portugal, one of the test-sites of project ASTARTE. Sines holds one of the most important deep-water ports which contains oil-bearing, petrochemical, liquid bulk, coal and container terminals. The port and its industrial infrastructures are facing the ocean southwest towards the main seismogenic sources. This work considers two different seis...

  20. Prevalence of antibodies to Leishmania infantum and Toxoplasma gondii in horses from the north of Portugal

    Science.gov (United States)

    Background Leishmania infantum and Toxoplasma gondii are protozoa with zoonotic and economic importance. Prevalences of antibodies to these agents were assessed in 173 horses from the north of Portugal. Findings Antibodies to L. infantum were detected by the direct agglutination test (DAT); seven (...

  1. Larvicidal activity against Aedes aegypti of Foeniculum vulgare essential oils from Portugal and Cape Verde.

    Science.gov (United States)

    Rocha, Diara Kady; Matosc, Olivia; Novoa, Maria Teresa; Figueiredo, Ana Cristina; Delgado, Manuel; Moiteiro, Cristina

    2015-04-01

    Dengue is a potentially fatal mosquito-borne infection with 50 million cases per year and 2.5 billion people vulnerable to the disease. This major public health problem has recurrent epidemics in Latin America and occurred recently in Cape Verde and Madeira Island. The lack of anti-viral treatment or vaccine makes the control of mosquito vectors a high option to prevent virus transmission. Essential oil (EO) constituents can affect insect's behaviour, being potentially effective in pest control. The present study evaluated the potential use of Foenicultm vulgare (fennel) EO in the control of the dengue vector Aedes aegypti. EOs isolated from fennel aerial parts collected in Cape Verde and from a commercial fennel EO of Portugal were analysed by NMR, GC and GC-MS. trans-Anethole (32 and 30%, respectively), limonene (28 and 18%, respectively) and fenchone (10% in both cases) were the main compounds identified in the EOs isolated from fennel from Cape Verde and Portugal, respectively. The larvicidal activity of the EOs and its major constituents were evaluated, using WHO procedures, against third instar larvae ofAe. aegypti for 24 h. Pure compounds, such as limonene isomers, were also assayed. The lethal concentrations LC50, C90 and LC99 were determined by probit analysis using mortality rates of bioassays. A 99% mortality of Ae. aegypti larvae was estimated at 37.1 and 52.4 µL L-1 of fennel EOs from Cape Verde and Portugal, respectively. Bioassays showed that fennel EOs from both countries displayed strong larvicidal effect against Ae. aegypti, the Cape Verde EO being as active as one of its major constituents, (-)-limonene.

  2. Dinâmicas atuais da enfermagem em Portugal: a representação dos enfermeiros Dinámicas actuales de la enfermeria en Portugal: la representación de los enfermeros Current dynamics of nursing in Portugal: nurses' representations

    Directory of Open Access Journals (Sweden)

    Felismina Rosa Parreira Mendes

    2010-04-01

    Full Text Available Trata-se de pesquisa qualitativa, com o objetivo de identificar as representações dos enfermeiros acerca das dinâmicas atuais da profissão, os marcos de sua evolução e as perspectivas futuras, realizada com vinte enfermeiros de Évora-Portugal, em abril/ maio de 2009, através de testemunhos narrativos. A formação ao longo dos anos e a Ordem dos Enfermeiros foram representadas como pilares centrais na construção da identidade profissional. A autonomia integra o cotidiano de cuidados, mas as questões hegemônicas de poder na equipe de saúde continuam a pautar a atuação dos enfermeiros e a balizar o seu auto e heterorreconhecimento profissional e social. As perspectivas futuras se direcionam para a empregabilidade, carreira e se consubstanciam na esperança de uns e na incerteza de outros.Se trata de pesquisa cualitativa con el objeto de identificar las representaciones de los enfermeros sobre las dinámicas actuales de la profesión, los hitos de su evolución y las perspectivas futuras, realizadas con veinte enfermeros de Évora en Portugal entre los meses de abril y mayo de 2009, por medio de declaraciones. La formación a lo largo de los años y la Orden de los Enfermeros fueron mostrados como pilares principales en la construcción de la identidad profesional. La autonomía integra los cuidados diarios, así como las cuestiones de hegemonía de poder en el equipo de salud que continúan a balizar la actuación de los enfermeros y a nortear su auto y heteroreconocimiento profesional y social. Las perspectivas futuras se direccionan para la empregabilidad, carrera y se consustancian en la esperanza de unos y la incertidumbre de otros.This research study, with a qualitative approach was carried out aiming to identify nurses' representation on current professional dynamics, evolutionary landmarks and the future outlook for Portuguese nursing with twenty nurses from Évora, Portugal, in April / May of 2009, through narrative

  3. Demonstrating managed aquifer recharge as a solution for climate change adaptation: results from Gabardine project and asemwaterNet coordination action in the Algarve region (Portugal

    Directory of Open Access Journals (Sweden)

    João Paulo Lobo Ferreira

    2014-09-01

    Full Text Available In the Algarve southern Portugal region, Managed Aquifer Recharge (MAR research activities have been developed to provide not only water surplus storage in aquifers during wet years, focusing in the Querença-Silves aquifer (FP6 ASEMWATERNet Coordination Action, but also groundwater quality rehabilitation in the Campina de Faro aquifer (FP6 Gabardine Project. Following MAR research potentialities in southern Portugal, this paper describes the objectives, conceptual demonstration, background and capabilities of one of the selected Circum-Mediterranean pilot sites (in Portugal that will be researched in the new FP7-ENV-2013-WATER-INNO-DEMO MARSOL project, which started Dec. 1st, 2013. In the Algarve pilot site, several case-study areas will be located in the Querença-Silves aquifer and in the Campina de Faro aquifer.

  4. Teaching Writing to Middle School Students in Portugal and in Brazil: An Exploratory Study

    Science.gov (United States)

    Veiga Simão, Ana Margarida; Malpique, Anabela Abreu; Frison, Lourdes Maria Bragagnolo; Marques, André

    2016-01-01

    Learning how to write is a challenging process, typically developed in schools. Teachers' practices in teaching writing, however, have been under researched. The aim of this study was to survey a sample of teachers from Portugal (n = 96) and Brazil (n = 99) about their practices for and perceptions about writing instruction. Teachers reported on…

  5. Participation et construction de barrage à Alqueva (Portugal. Quelles méthodes, quels moyens ?

    Directory of Open Access Journals (Sweden)

    Fabienne Wateau

    2004-12-01

    Full Text Available Ce n’est pas la participation qui est en cause, mais les façons inadaptées ou faussement démocratiques et légitimatrices de la présenter. Quelques-unes de ces situations, dans le contexte de la construction d’un grand barrage au Portugal, sont explicitées dans cet article.

  6. Regulação, circulação e distribuição da penicilina em Portugal (anos 40 e 50 do século XX)

    OpenAIRE

    Bell, Victoria; Pita, João Rui; Pereira, Ana Leonor

    2017-01-01

    Estudar a regulação, circulação e distribuição da penicilina em Portugal nos anos 40 e 50 do século XX. Estudo realizado no Arquivo da Cruz Vermelha Portuguesa e no Arquivo da Universidade de Coimbra. Conclui-se que Portugal teve uma exemplar regulação e distribuição da penicilina

  7. Shallow and deep landslides induced by rainfall in the Lisbon region (Portugal: assessment of relationships with the North Atlantic Oscillation

    Directory of Open Access Journals (Sweden)

    J. L. Zêzere

    2005-01-01

    Full Text Available The aim of this study is to assess the impact of the North Atlantic Oscillation (NAO on both the winter precipitation and the temporal occurrence of different landslide types in Portugal. The analysis is applied to five sample areas located just north of Lisbon, the capital of Portugal. These sites are particularly relevant because actual dates of most of the recent landslide events are known but also because the landslides occurred in a suburban area with growing urbanization pressure. Results show that the large inter-annual variability of winter precipitation observed in western Iberia, i.e. Portugal and parts of Spain, is largely modulated by the NAO mode. In particular, precipitation falling in Portugal between November and March presents a correlation coefficient of R=–0.66 with the NAO index. Precipitation distribution for the reference rain gauge in the study area reveals that the probability of a wet month to occur is much higher for low NAO index composites than for the corresponding high NAO index composite. It is shown that this control, exerted by NAO on the precipitation regime, is related to corresponding changes in the associated activity of North-Atlantic storm tracks that affect the western Iberia. Landslide activity in the study area is related to both intense, short duration precipitation events (1–15 days and long-lasting rainfall episodes (1–3 months. The former events trigger shallow translational slides while the later episodes are usually associated with deeper and larger slope movements. This second group of landslides is shown to be statistically associated with the 3-month average of the NAO index.

  8. [The Road towards the Responsible and Safe Legalization of Cannabis Use in Portugal].

    Science.gov (United States)

    Baptista-Leite, Ricardo; Ploeg, Lisa

    2018-02-28

    Recently, the world has seen examples of the legalization of cannabis for recreational purposes. Due to the diversity of experiences in progress, it is urgent to analyze the impacts of this legalization, from a public health perspective. Therefore, this article aims to review the accumulated knowledge in the states and countries where the use of cannabis is legal and to ponder over the relevance of starting a similar path towards legalization in Portugal, thus supporting political decisions to be properly informed and evidence-based. An extensive literature review was performed using databases and scientific journals, such as PubMed, as well as the search of institutional documentation, including the EMCDDA and SICAD. The gathered information provided insights and enabled assessment of (1) the acute and chronic effects of cannabis use on health, (2) the Portuguese situation related to cannabis and (3) the processes and lessons learned after the legalization of cannabis in other countries or states. Given the above, and according to the data presented, the authors argue for a safe and responsible strategy towards the legalization of cannabis use in Portugal. In accordance, a set of concrete proposals are presented. From a public health perspective, it is assumed that the interest of this proposal is to reduce the problematic use of cannabis, to effectively fight against illicit drug trafficking and drug-related crime, as well as health promotion and prevention of addictions and other adverse health impacts. This article reveals that the effects of legalization might, contrary to general beliefs, generate positive results with respect to these aims, given that there will be greater control on the market, price, quality, and information - to name a few - if implementation occurs with proper consideration and definition. The debate on the responsible and safe legalization of cannabis use in Portugal should be open and promoted, based on a public health

  9. The demise of multidrug-resistant HIV-1: the national time trend in Portugal

    Science.gov (United States)

    Vercauteren, Jurgen; Theys, Kristof; Carvalho, Ana Patricia; Valadas, Emília; Duque, Luis Miguel; Teófilo, Eugénio; Faria, Telo; Faria, Domitília; Vera, José; Águas, Maria João; Peres, Susana; Mansinho, Kamal; Vandamme, Anne-Mieke; Camacho, Ricardo Jorge; Mansinho, Kamal; Cláudia Miranda, Ana; Aldir, Isabel; Ventura, Fernando; Nina, Jaime; Borges, Fernando; Valadas, Emília; Doroana, Manuela; Antunes, Francisco; João Aleixo, Maria; João Águas, Maria; Botas, Júlio; Branco, Teresa; Vera, José; Vaz Pinto, Inês; Poças, José; Sá, Joana; Duque, Luis; Diniz, António; Mineiro, Ana; Gomes, Flora; Santos, Carlos; Faria, Domitília; Fonseca, Paula; Proença, Paula; Tavares, Luís; Guerreiro, Cristina; Narciso, Jorge; Faria, Telo; Teófilo, Eugénio; Pinheiro, Sofia; Germano, Isabel; Caixas, Umbelina; Faria, Nancy; Paula Reis, Ana; Bentes Jesus, Margarida; Amaro, Graça; Roxo, Fausto; Abreu, Ricardo; Neves, Isabel

    2013-01-01

    Objectives Despite a decreasing mortality and morbidity in treated HIV-1 patients, highly active antiretroviral treatment (HAART) can still fail due to the development of drug resistance. Especially, multidrug-resistant viruses pose a threat to efficient therapy. We studied the changing prevalence of multidrug resistance (MDR) over time in a cohort of HIV-1-infected patients in Portugal. Patients and methods We used data of 8065 HIV-1-infected patients followed from July 2001 up to April 2012 in 22 hospitals located in Portugal. MDR at a specific date of sampling was defined as no more than one fully active drug (excluding integrase and entry inhibitors) at that time authorized by the Portuguese National Authority of Medicines and Health Products (INFARMED), as interpreted with the Rega algorithm version 8.0.2. A generalized linear mixed model was used to study the time trend of the prevalence of MDR. Results We observed a statistically significant decrease in the prevalence of MDR over the last decade, from 6.9% (95% CI: 5.7–8.4) in 2001–03, 6.0% (95% CI: 4.9–7.2) in 2003–05, 3.7% (95% CI: 2.8–4.8) in 2005–07 and 1.6% (95% CI: 1.1–2.2) in 2007–09 down to 0.6% (95% CI: 0.3–0.9) in 2009–12 [OR = 0.80 (95% CI: 0.75–0.86); P < 0.001]. In July 2011 the last new case of MDR was seen. Conclusions The prevalence of multidrug-resistant HIV-1 is decreasing over time in Portugal, reflecting the increasing efficiency of HAART and the availability of new drugs. Therefore, in designing a new drug, safety and practical aspects, e.g. less toxicity and ease of use, may need more attention than focusing mainly on efficacy against resistant strains. PMID:23228933

  10. Water resources and sustainable development: planning requirements and shared management between Spain and Portugal; Recursos hidricos y desarrollo sostenible: requisitos para la planificacion y gestion compartida entre Espana y Portugal

    Energy Technology Data Exchange (ETDEWEB)

    Lopez Lopez, A.

    2011-07-01

    The Earth has a constant quantity of water, but suffers hydric stress and forecast of future is not optimistic. Thus, the UN in the Millennium Development Goals for 2015 establishes special reference to the issues of water. This paper highlights the indicators of sustainability for the hydric resources and proposes an ecosistemic model of eco-social efficiency for the sharing planning and management between Spain and Portugal. (Author)

  11. Interpretation of SO2 dry deposition measurements made in Portugal and Spain within the framework of SREMP

    NARCIS (Netherlands)

    Erisman JW; LLO

    1996-01-01

    Het RIVM heeft deelgenomen aan het internationale project SREMP (Surface Resistance Emergency Measurement Program), tezamen met de Universiteit van Aveiro, Portugal ; de Universiteit Politecnica uit Madrid, Spanje ; de Universiteit Paul Sabatier de Toulouse, Frankrijk ; Joint Research Center,

  12. Development of a hybrid paclitaxel-loaded arsenite nanoparticle (HPAN) delivery system for synergistic combined therapy of paclitaxel-resistant cancer

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Fei-yan; Zhang, Yu [Nanchang University, College of Chemistry (China); Chen, Xiang-yu [Xiangya No.2 Hospital of Central South University, Department of Radiology (China); Li, Jia-qian; Xiao, Xiao-ping; Yu, Lu-lu; Tang, Qun, E-mail: tangqun@ncu.edu.cn [Nanchang University, Institute for Advanced Study (China)

    2017-04-15

    Multidrug resistance (MDR) is a major reason for failure of chemotherapy in a variety of human tumors. For instance, paclitaxel (PTX) has been widely used as a first-line anticancer drug, but resistance to PTX is becoming increasingly serious. Herein, we propose a strategy of combined therapy to overcome MDR of PTX by introducing a hybrid paclitaxel-loaded gadolinium arsenite nanoparticle (HPAN), where PTX was conjugated with rod-shaped gadolinium arsenite (GdAsO{sub x}) nanoparticle (NP). Triggered by endogenous inorganic phosphate (Pi), the hybrid nanoparticles readily collapse, thereby releasing PTX and arsenic trioxide (ATO). An MTT assay indicated IC50 values for HPAN one order of magnitude lower than for a simple equivalent mixture of PTX and ATO against PTX-resistant human colon cancer cells (HCT 166), indicating remarkable synergistic effect. Species type-dependent cellular uptake, induced apoptosis, and cell cycle modulation were also evaluated. Cellular uptake tests indicate that the HPAN presents higher PTX intracellular loading for the PTX-resistant cells and longer intracellular retention time, displaying resistance to drug efflux from the cancer cell than pristine PTX or the equivalent mixture of PTX and ATO. Cell cycle and apoptosis tests consistently proved that addition of HPAN resulted in higher G2/M and apoptosis in PTX-resistant cells. In vivo anticancer experiments evidenced that HPAN had better therapeutic effect on the resistant tumor in the murine xenograft model than pristine PTX or a mixture of PTX and ATO. Our results suggest that HPAN might enhance the therapeutic index and overcome PTX resistance and also demonstrate that the combined therapy is not only related to the species of combined agents but also their physiochemical states.

  13. The expression of endothelial and inducible nitric oxide synthase and apoptosis in intestinal ischemia and reperfusion injury under the action of ischemic preconditioning and pentoxifylline.

    Science.gov (United States)

    Oliveira, Teresinha Regina Ribeiro de; Oliveira, Geraldo Ferreira de; Simões, Ricardo Santos; Feitosa, Suellen Maurim; Tikazawa, Eduardo Hiroshi; Monteiro, Hugo Pequeno; Fagundes, Djalma José; Taha, Murched Omar

    2017-11-01

    To investigate the expression of nitric oxide synthase (NOS) and apoptosis associated with ischemic preconditioning (IPC) and pentoxifylline (PTX) in intestinal ischemia (I) and reperfusion (R) injury. Thirty male rats were assigned to 5 groups: (CG), no clamping of the superior mesenteric artery (90 minutes); (IR-SS) saline + ischemia (30 minutes) + reperfusion (60 minutes); (IR-PTX) PTX + ischemia (30 minutes) + reperfusion (60 minutes); (IPC-IR-SS) 5 minutes of ischemia + 5 minutes of reperfusion (IPC) + saline + I(30 minutes)+R(60 minutes); and (IPC-IR-PTX) IPC + PTX + I(30 minutes)+ R(60 minutes). The application of IPC and PTX showed a significantly lower immunohistochemistry reaction for active caspase-3 (P0.05). The NOS-2 expression (qRTPCR) in the IR-PTX group (P<0.05) was higher than the values for the IPC+IR-SS and IPC-IR-PTX groups. The NOS-3 expression was significantly upper in the IPC-IR-PTX group than in the CG (P<0.05), the IR-SS (P<0.05) and the IR-PTX (P<0.05) groups. The BCL-2 and active caspase-3 showed beneficial effects on PTX and IPC. The expression of NOS-2 and NOS-3 in the IPC and IPC-PTX groups showed no synergistic effect.

  14. O franchising como paradigma de crescimento das PME em Portugal

    OpenAIRE

    Carvalhosa, José Manuel Pinto

    2011-01-01

    Mestrado em Controlo e Gestão dos Negócios O tecido empresarial português assenta maioritariamente em organizações com características que se enquadram na categoria denominada de pequenas e médias empresas. Consequentemente gozam de enorme relevância e influência na economia nacional. O franchising teve origem nos Estados Unidos da América e começou a dar os primeiros passos no início do século passado. A introdução em Portugal deste conceito foi mais recente, final da dé...

  15. THE SOCIAL PERCEPTION OF NATURAL HAZARDS RISK: PORTUGAL AND TUVALU

    OpenAIRE

    Rodrigo Rudge Ramos Ribeiro; Celeste Oliveira Alves Coelho

    2012-01-01

    Los efectos del cambio climático y del nivel del mar deben causar graves problemas para los habitantes de algunas pequeñas islas como Tuvalu en el futuro. Como resultado de una combinación de procesos naturales y acción antropogénica, el cambio del nivel del mar genera un impacto diferente. Esta investigación aborda la percepción del riesgo natural y del cambio climático en Portugal y Tuvalu. La percepción de algunos riesgos naturales, como la subida del nivel del mar, puede ser distinta para...

  16. Exploring the Relationship between Institutional and Professional Autonomy: A Comparative Study between Portugal and Finland

    Science.gov (United States)

    Carvalho, Teresa; Diogo, Sara

    2018-01-01

    By comparing two distinct settings--Portugal and Finland--and based on previous studies revealing similar trends in both countries, this article analyses the relationship between institutional and academic autonomy in the higher education sector. Based on crosschecking of the literature review and 47 interviews with key actors in both the…

  17. Using cellular automata to simulate forest fire propagation in Portugal

    Science.gov (United States)

    Freire, Joana; daCamara, Carlos

    2017-04-01

    Wildfires in the Mediterranean region have severe damaging effects mainly due to large fire events [1, 2]. When restricting to Portugal, wildfires have burned over 1:4 million ha in the last decade. Considering the increasing tendency in the extent and severity of wildfires [1, 2], the availability of modeling tools of fire episodes is of crucial importance. Two main types of mathematical models are generally available, namely deterministic and stochastic models. Deterministic models attempt a description of fires, fuel and atmosphere as multiphase continua prescribing mass, momentum and energy conservation, which typically leads to systems of coupled PDEs to be solved numerically on a grid. Simpler descriptions, such as FARSITE, neglect the interaction with atmosphere and propagate the fire front using wave techniques. One of the most important stochastic models are Cellular Automata (CA), in which space is discretized into cells, and physical quantities take on a finite set of values at each cell. The cells evolve in discrete time according to a set of transition rules, and the states of the neighboring cells. In the present work, we implement and then improve a simple and fast CA model designed to operationally simulate wildfires in Portugal. The reference CA model chosen [3] has the advantage of having been applied successfully in other Mediterranean ecosystems, namely to historical fires in Greece. The model is defined on a square grid with propagation to 8 nearest and next-nearest neighbors, where each cell is characterized by 4 possible discrete states, corresponding to burning, not-yet burned, fuel-free and completely burned cells, with 4 possible rules of evolution which take into account fuel properties, meteorological conditions, and topography. As a CA model, it offers the possibility to run a very high number of simulations in order to verify and apply the model, and is easily modified by implementing additional variables and different rules for the

  18. Bevacizumab Exacerbates Paclitaxel-Induced Neuropathy: A Retrospective Cohort Study.

    Directory of Open Access Journals (Sweden)

    Ayumu Matsuoka

    Full Text Available Bevacizumab (BEV, a humanized anti-vascular endothelial growth factor (VEGF monoclonal antibody, enhances the antitumor effectiveness of paclitaxel (PTX-based chemotherapy in many metastatic cancers. A recent study in mice showed that VEGF receptor inhibitors can interfere with the neuroprotective effects of endogenous VEGF, potentially triggering the exacerbation of PTX-induced neuropathy. In clinical trials, exacerbation of neuropathy in patients who received PTX combined with BEV (PTX+BEV has generally been explained by increased exposure to PTX owing to the extended duration of chemotherapy. We investigated whether the concurrent use of BEV is associated with the exacerbation of PTX-induced neuropathy.Female patients with breast cancer who had received weekly PTX or PTX+BEV from September 2011 through May 2016 were studied retrospectively. PTX-induced neuropathy was evaluated at the same time points (at the 6th and 12th courses of chemotherapy in both cohorts. A multivariate Cox proportional-hazards model was used to assess the independent effect of BEV on the time to the onset of neuropathy.A total of 107 patients (median age, 55 years; range, 32-83 were studied. Sixty-one patients received PTX as adjuvant chemotherapy, 23 received PTX for metastatic disease, and 23 received PTX+BEV for metastatic disease. Peripheral sensory neuropathy was worse in patients who received PTX+BEV than in those who received PTX alone: at the 6th course, Grade 0/1/2/3 = 4/13/4/0 vs. 25/42/6/0 (P = 0.095; at the 12th course, 2/3/11/3 vs. 7/30/23/2 (P = 0.016. At the 12th course, the incidence of Grade 2 or higher neuropathy was significantly higher in patients treated with PTX+BEV than in those treated with PTX alone (74% vs. 40%; P = 0.017. In multivariate analysis, BEV was significantly associated with an increased risk of neuropathy (HR 2.32, 95% CI 1.21-4.44, P = 0.012.The concurrent use of BEV could worsen PTX-induced neuropathy in patients with breast

  19. El voto religioso en España y Portugal

    Directory of Open Access Journals (Sweden)

    Montero, Jóse Ramón

    2008-12-01

    Full Text Available This article explores the relationship between religiosity and voting decisions in Spain and Portugal. We study whether religion (measured as church attendance and opinions about moral issues influences voting for the two main political parties. Results show a different relationship between religion and voting in both countries: only in Spain religious beliefs play an important role in electoral behaviour. We claim that to account for this finding several factors need to be considered, namely the different configuration of the party systems and religious maps, the distinctive mechanisms linking religious identities with voting and, above all, the important role played by political leaders in activating religiosity within the electoral competition.

    Este artículo explora la relación entre la religiosidad y las preferencias electorales en España y Portugal. Estudiamos si la religión (medida como asistencia a oficios religiosos y opiniones sobre asuntos morales tiene influencia sobre el voto a los dos principales partidos nacionales. Los resultados del análisis apuntan a una relación diferente entre religión y voto en ambos países: sólo en España las creencias religiosas desempeñan un papel destacado en el comportamiento electoral. Defendemos que la explicación a este hallazgo se encuentra en un conjunto de factores entre los que cabe destacar la diferente configuración del sistema de partidos y de los mapas religiosos, los distintos mecanismos que canalizan las identidades religiosas hacia el voto y, fundamentalmente, el importante papel desempeñado por las elites políticas en la activación de la religiosidad dentro de la competición electoral.

  20. [Thromboprophylaxis in critically ill children in Spain and Portugal].

    Science.gov (United States)

    Rodríguez Núñez, A; Fonte, M; Faustino, E V S

    2015-03-01

    Although critically ill children may be at risk from developing deep venous thrombosis (DVT), data on its incidence and effectiveness of thromboprophylaxis are lacking. To describe the use of thromboprophylaxis in critically ill children in Spain and Portugal, and to compare the results with international data. Secondary analysis of the multinational study PROTRACT, carried out in 59 PICUs from 7 developed countries (4 from Portugal and 6 in Spain). Data were collected from patients less than 18 years old, who did not receive therapeutic thromboprophylaxis. A total of 308 patients in Spanish and Portuguese (Iberian) PICUS were compared with 2176 admitted to international PICUs. Risk factors such as femoral vein (P=.01), jugular vein central catheter (P<.001), cancer (P=.03), and sepsis (P<.001), were more frequent in Iberian PICUs. The percentage of patients with pharmacological thromboprophylaxis was similar in both groups (15.3% vs. 12.0%). Low molecular weight heparin was used more frequently in Iberian patients (P<.001). In treated children, prior history of thrombosis (P=.02), femoral vein catheter (P<.001), cancer (P=.02) and cranial trauma or craniectomy (P=.006), were more frequent in Iberian PICUs. Mechanical thromboprophylaxis was used in only 6.8% of candidates in Iberian PICUs, compared with 23.8% in the international PICUs (P<.001). Despite the presence of risk factors for DVT in many patients, thromboprophylaxis is rarely prescribed, with low molecular weight heparin being the most used drug. Passive thromboprophylaxis use is anecdotal. There should be a consensus on guidelines of thromboprophylaxis in critically ill children. Copyright © 2014 Asociación Española de Pediatría. Published by Elsevier España, S.L.U. All rights reserved.