WorldWideScience

Sample records for political candidates studies

  1. Aspirant candidate behaviour and progressive political ambition

    Directory of Open Access Journals (Sweden)

    Peter Allen

    2017-02-01

    Full Text Available In this paper we take account of the role of aspirant candidate behaviour in progressive political ambition, specifically how some individuals signal their political ambition to political actors by approaching them to discuss running for office. We examine how the effect of this behaviour compares to the more prominently studied effect of elite recruitment. We conclude that signalling behaviour by an aspirant candidate has a substantial effect, particularly with regard to actually acting on initial considerations of whether to stand, and that elite recruitment makes a difference but only in conjunction with the aspirant candidate themselves signalling their ambition to political actors.

  2. Political Candidate Campaign Advertising: A Selected Review of the Literature.

    Science.gov (United States)

    Hellweg, Susan A.

    This paper provides a selected review of political candidate campaign advertising studies from the political science, mass communication, advertising, and political communication literature. The paper examines the literature in terms of research pertaining to (1) candidate advertising content (commercials for male versus female candidates and for…

  3. Communication Styles and Female Candidates: A Study of the Political Advertising during the 1986 Senate Elections.

    Science.gov (United States)

    Johnston, Anne; White, Anne Barton

    1994-01-01

    Explores communication strategies and styles used in television advertising by female U.S. Senate candidates for the 1986 elections. Finds that they focused on issues and stayed away from negative advertising in their ads, tending to highlight their competency as political officials and their past accomplishments. (SR)

  4. How political candidates use Twitter and the impact on votes

    NARCIS (Netherlands)

    Kruikemeier, S.

    2014-01-01

    This study investigates the content characteristics of Twitter during an election campaign, and the relationship between candidates’ style of online campaigning (i.e., politically personalized and interactive communication) and electoral support for those candidates. Thereby, it provides a better

  5. Practicing Politics: Female Political Scientists as Candidates for Elective Office

    Science.gov (United States)

    Burrell, Barbara

    2012-01-01

    In 2007, University of Oklahoma political science professor Cindy Simon Rosenthal was elected mayor of Norman, Oklahoma, after having served as a member of its city council. Was her activity unique within the political science profession among female political scientists? Her election stimulated the curiosity of some of us in the…

  6. Candidate Political Philosophy: Revelations in the 1960 and 1976 Debates.

    Science.gov (United States)

    Meadow, Robert G.; Jackson-Beeck, Marilyn

    Since voters rarely have access to a candidate's unexpurgated statements, they rely on political advertising, film footage, and media interpretations. Thus, their expectations of candidates generally reflect selective reporting and self-aggrandizement. A framework for researching the degree of understanding reached between politicians and the…

  7. Image versus text: How newspaper reports affect evaluations of political candidates

    NARCIS (Netherlands)

    Boomgaarden, H.G.; Boukes, M.; Iorgoveanu, A.

    2016-01-01

    News coverage has become more visual and research suggests that news images affect assessments of political candidates. This study experimentally investigates the effects of textual versus visual on assessments of politicians’ competency and integrity, differentially for males and females. The

  8. 47 CFR 73.4190 - Political candidate authorization notice and sponsorship identification.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false Political candidate authorization notice and sponsorship identification. 73.4190 Section 73.4190 Telecommunication FEDERAL COMMUNICATIONS COMMISSION....4190 Political candidate authorization notice and sponsorship identification. (a) See Joint Public...

  9. Military and Political Studies

    Directory of Open Access Journals (Sweden)

    Alexey I. Podberyozkin

    2014-01-01

    Full Text Available Military-political issues is an important area of research work at MGIMO. The difference in this direction from the classical international specialization is that it is at the intersection of several disciplines: military science, military-technical and military-industrial as well as International Relations. A specialist in military and political issues should not only be an expert in the field of international relations and diplomacy, but also have a deep knowledge of military-technical issues to understand the basic trends in the development of scientific and technological progress and its impact on the balance of forces in the world. Global changes in the balance of power and the nature of the conflict, the emergence of new types of weapons are changing the basic methods and approaches to the art of war, which requires a science-based perspective on problem solving and multi-disciplinary approach in achieving the goals. Military and political studies allow us to understand how the development of military technology and military organization of the state affected by the political situation in the world, the national security of the country and its place in the system of international relations. Military-political research has been developing at MGIMO for a few decades. It laid down the basis for a scientific school of political-military studies. Its founding fathers were such prominent scholars of international affairs, as I.G. Usachyov, A.D. Nikonov, A.G. Arbatov, V.G. Baranovsky, V.M. Kulagin, A.N. Nikitin and other well-known experts. Their work covers a wide range of military and political issues, including the topics of arms control and disarmament, international, and especially European security, military policy, NATO, the Western military-political doctrines and their practical application. Now the lead in the development of this research at MGIMO has taken Center for Military-Political Studies, which became a concentration of relevant

  10. CANDIDATES IN THE PRESIDENTIAL ELECTIONS IN ROMANIA (2014: THE USE OF SOCIAL MEDIA IN POLITICAL MARKETING

    Directory of Open Access Journals (Sweden)

    Monica Patrut

    2015-07-01

    Full Text Available The phenomenon of social media has drawn the attention of the specialists from the political marketing because it contributes quickly and efficiently to the increase of the political product’s visibility and appeals to its supporters for content creation and viral promotion of the political messages. In addition, the candidate can communicate directly with the citizens and may involve them in creating virtual communities. In our study we briefly present the way in which social media was used, timidly at first, during the campaign for the 2008 parliamentary elections, for the 2009 presidential elections and for the 2012 local and parliamentary elections. The importance of social media increased during the 2012 Romanian presidential impeachment referendum and contributed decisively to rallying voters to go to the polls and, implicitly, to the Klaus Iohannis’s victory in the 2014 presidential elections. We have focused especially on Facebook, as social network, because it has managed to attract the largest number of users in Romania. The success of the 2.0 political actors does not imply (only to use the network as an alternative news channel, but especially to establish the bidirectional connection and constant interaction with virtual friends.

  11. Political Correctness and Cultural Studies.

    Science.gov (United States)

    Carey, James W.

    1992-01-01

    Discusses political correctness and cultural studies, dealing with cultural studies and the left, the conservative assault on cultural studies, and political correctness in the university. Describes some of the underlying changes in the university, largely unaddressed in the political correctness debate, that provide the deep structure to the…

  12. 78 FR 71535 - Guidance for Tax-Exempt Social Welfare Organizations on Candidate-Related Political Activities

    Science.gov (United States)

    2013-11-29

    ... political campaigns on behalf of or in opposition to any candidate for public office.'' Treas. Reg. Sec. 1... or distributing of statements), any political campaign on behalf of (or in opposition to) any candidate for public office'' (``political campaign intervention''). However, unlike the absolute...

  13. 78 FR 76032 - Date of Political Party Nominations of Candidates for Special Primary Elections in New York

    Science.gov (United States)

    2013-12-16

    ... 11 CFR Part 100 Date of Political Party Nominations of Candidates for Special Primary Elections in... election under New York law is the date on which the political party committee votes to nominate the party... . . . a convention or caucus of a political party which has authority to nominate a candidate.'' 2 U.S.C...

  14. Speaking two "Languages" in America: A semantic space analysis of how presidential candidates and their supporters represent abstract political concepts differently.

    Science.gov (United States)

    Li, Ping; Schloss, Benjamin; Follmer, D Jake

    2017-10-01

    In this article we report a computational semantic analysis of the presidential candidates' speeches in the two major political parties in the USA. In Study One, we modeled the political semantic spaces as a function of party, candidate, and time of election, and findings revealed patterns of differences in the semantic representation of key political concepts and the changing landscapes in which the presidential candidates align or misalign with their parties in terms of the representation and organization of politically central concepts. Our models further showed that the 2016 US presidential nominees had distinct conceptual representations from those of previous election years, and these patterns did not necessarily align with their respective political parties' average representation of the key political concepts. In Study Two, structural equation modeling demonstrated that reported political engagement among voters differentially predicted reported likelihoods of voting for Clinton versus Trump in the 2016 presidential election. Study Three indicated that Republicans and Democrats showed distinct, systematic word association patterns for the same concepts/terms, which could be reliably distinguished using machine learning methods. These studies suggest that given an individual's political beliefs, we can make reliable predictions about how they understand words, and given how an individual understands those same words, we can also predict an individual's political beliefs. Our study provides a bridge between semantic space models and abstract representations of political concepts on the one hand, and the representations of political concepts and citizens' voting behavior on the other.

  15. Differential Effects of Right-Wing Authoritarianism and Social Dominance Orientation on Political Candidate Support: The Moderating Role of Message Framing

    Directory of Open Access Journals (Sweden)

    Jarret T. Crawford

    2013-09-01

    Full Text Available Employing a dual process motivational (DPM model perspective, we found that how political messages are framed influences the differential effects of right-wing authoritarianism (RWA and social dominance orientation (SDO on political candidate support in the United States. Study 1 (N = 85 found that RWA and SDO differentially predicted support for right-wing candidates who used cohesion and group status threats to frame same-sex marriage, respectively. Study 2 (N = 89 largely replicated those findings on immigration policy. In Study 3 (N = 128, the hypothesis that RWA and SDO negatively predicted support for left-wing candidates who framed same-sex marriage in terms of individual liberty and social equality, respectively, received partial support. Additional analyses indicated that the effects of RWA on candidate support in these studies were driven by specific theoretically-relevant dimensions of RWA. Together, these results indicate that candidates can enhance their appeal by strategically employing value-based political messages targeting different subsets of their constituency.

  16. Is the political animal politically ignorant? Applying evolutionary psychology to the study of political attitudes.

    Science.gov (United States)

    Petersen, Michael Bang; Aarøe, Lene

    2012-12-20

    As evidenced by research in evolutionary psychology, humans have evolved sophisticated psychological mechanisms tailored to solve enduring adaptive problems of social life. Many of these social problems are political in nature and relate to the distribution of costs and benefits within and between groups. In that sense, evolutionary psychology suggests that humans are, by nature, political animals. By implication, a straightforward application of evolutionary psychology to the study of public opinion seems to entail that modern individuals find politics intrinsically interesting. Yet, as documented by more than fifty years of research in political science, people lack knowledge of basic features of the political process and the ability to form consistent political attitudes. By reviewing and integrating research in evolutionary psychology and public opinion, we describe (1) why modern mass politics often fail to activate evolved mechanisms and (2) the conditions in which these mechanisms are in fact triggered.

  17. Vote Choice, Ideology, and Social Dominance Orientation Influence Preferences for Lower Pitched Voices in Political Candidates

    DEFF Research Database (Denmark)

    Laustsen, Lasse; Petersen, Michael Bang; A. Klofstad, Casey

    2015-01-01

    in modern elections with lower-pitched voices are generally more successful. As lower-pitched voices are perceived as stronger and more dominant, these findings have been taken to indicate a general preference for dispositional abilities in leaders to protect and prevail in conflicts. Here we extend upon...... among liberal Democrats. In a third study we show that preferences for lower-pitched candidate voices stem from individual differences in Social Dominance Orientation (SDO). Importantly, across all three studies subjects’ party affiliation, ideology, and SDO only predict references for male candidate...

  18. Neuroelectrical Correlates of Trustworthiness and Dominance Judgments Related to the Observation of Political Candidates

    Directory of Open Access Journals (Sweden)

    Giovanni Vecchiato

    2014-01-01

    Full Text Available The present research investigates the neurophysiological activity elicited by fast observations of faces of real candidates during simulated political elections. We used simultaneous recording of electroencephalographic (EEG signals as well as galvanic skin response (GSR and heart rate (HR as measurements of central and autonomic nervous systems. Twenty healthy subjects were asked to give judgments on dominance, trustworthiness, and a preference of vote related to the politicians’ faces. We used high-resolution EEG techniques to map statistical differences of power spectral density (PSD cortical activity onto a realistic head model as well as partial directed coherence (PDC and graph theory metrics to estimate the functional connectivity networks and investigate the role of cortical regions of interest (ROIs. Behavioral results revealed that judgment of dominance trait is the most predictive of the outcome of the simulated elections. Statistical comparisons related to PSD and PDC values highlighted an asymmetry in the activation of frontal cortical areas associated with the valence of the judged trait as well as to the probability to cast the vote. Overall, our results highlight the existence of cortical EEG features which are correlated with the prediction of vote and with the judgment of trustworthy and dominant faces.

  19. Election of candidates to municipal presidency of political parties in Ciudad Juarez and as practice and internal democracy strengthening

    Directory of Open Access Journals (Sweden)

    Cecilia Sarabia Ríos

    2011-07-01

    Full Text Available The internal democratic of political parties are one of the numerous analyses that can be performed on an electoral process. In this regard, this document aims to understand the logic of development of internal democracy in the party organizations in Ciudad Juarez, focusing on one aspect of it: the selection of candidates. The observation of the selection of candidates for municipal office in the last decade in Ciudad Juarez allowed to comment the advantages and disadvantages for the internal democratic life of party, to understand its development level and the logic that motivates their evolution or turn to be attractive only for external voting and not for the militants.

  20. The influence of political candidates' facial appearance on older and younger adults' voting choices and actual electoral success.

    Science.gov (United States)

    Franklin, Robert G; Zebrowitz, Leslie A

    2016-01-01

    Younger adults (YA) judgments of political candidates' competence from facial appearance accurately predict electoral success. Whether this is true for older adults (OA) has not been investigated despite the fact that OA are more likely to vote than YA and may respond differently to particular facial qualities. We examined whether OA and YA ratings of competence, trustworthiness, attractiveness, and babyfaceness of opposing candidates in US Senate elections independently predicted their own vote choices and actual election outcomes. OA and YA ratings of attractiveness, competence, and trustworthiness positively predicted their choices, but the effect of competence was weaker for OA. Babyfaceness negatively predicted OA, but not YA, choices. OA and YA competence ratings equally predicted the actual election winners, while OA, but not YA, attractiveness ratings did so. Trustworthy and babyface ratings did not predict actual winners. These findings have implications for understanding age differences in candidate preferences and the prediction of election outcomes.

  1. Losing on all fronts: the effects of negative versus positive person-based campaigns on implicit and explicit evaluations of political candidates.

    Science.gov (United States)

    Carraro, Luciana; Gawronski, Bertram; Castelli, Luigi

    2010-09-01

    The current research investigated the effects of negative as compared to positive person-based political campaigns on explicit and implicit evaluations of the involved candidates. Participants were presented with two political candidates and statements that one of them ostensibly said during the last political campaign. For half of the participants, the campaign included positive remarks about the source of the statement (positive campaign); for the remaining half, the campaign included negative remarks about the opponent (negative campaign). Afterwards, participants completed measures of explicit and implicit evaluations of both candidates. Results indicate that explicit evaluations of the source, but not the opponent, were less favourable after negative as compared to positive campaigns. In contrast, implicit evaluations were less favourable for both candidates after negative campaigns. The results are discussed in terms of associative and propositional processes, highlighting the importance of associative processes in political decision making.

  2. Multicultural Politics In Governor Candidates Of Dki Jakarta 2017 In Tempo.Co

    Directory of Open Access Journals (Sweden)

    Diya Sri Widiyanti

    2017-06-01

    Full Text Available The purpose of this research is how to comprehend the politics of Indonesian people for accepting ethnic, racial, religious and tribal diversity in occupying government seat (governor’s election of Jakarta in the context of multicultural country. This research uses Michel Foucaul’s theory, especially in implementing the discourse of  " indigenous Indonesian leader " in people’s mind.  Foucaul’s critical discourse analyses alone does not fully answer the issues of politics in Indonesia, therefore this research also uses Jacques Ranciere's theory in its democratic spirit and the multicultural view of Bhikhu Parekh. The result of the research are society’s heterophobia of multicultural politics, the emerging burden of multicultural politics in Indonesia, antagonism,  failures in politics, and epilogue, becoming a difference border. The conclusion is, issue of SARA (ethnicity, religion, race, intergroups still exists, especially in a country with multicultural status. Politics and multicultural discourses which do not find the logic of the equation is not the dissensus, but consensus.

  3. Recruitment and political career entrance: legislative candidates in Rio Grande do Sul (1998 – 2006

    Directory of Open Access Journals (Sweden)

    Rodrigo da Rosa Bordignon

    2017-06-01

    Full Text Available This work is the result of a previously made research centered on the general problem of the relations between the social space’s structure and the political space, and its effects to the chances and modalities of entrance in politics.The proposed analysis is centered on the examination of the relationship between social resources, parties and electoral competition´s modality of entrance.The main goal is to apprehend the ways through which oppositions that constitute the electoral competition space are defined. To this end, information collected at TRE-RS were used and confronted to the justification modes when entering the dispute over positions of political representation. The main indications point to an association between social positioning resources, parties and electoral competition´s modalities of entrance.

  4. Politics and language rights: a case study of language politics in Croatia

    OpenAIRE

    Pupavac, Vanessa

    2003-01-01

    This chapter discusses language and national aspirations through a case study of language politics in Croatia. Not only is language crucially influenced by national politics, but language politics has played a significant role in national politics in which the status accorded to regional variations in language has paralleled political aspirations. Claims to a distinct Croatian language and rejection of a shared Serbo-Croatian language have been a key part in the Croatian nation-building proce...

  5. Social Studies Teacher Candidates' Views on Historical Thinking Skills

    Science.gov (United States)

    Ozmen, Cengiz

    2015-01-01

    Current study aimed to present Social Studies teacher candidates' views on historical thinking skills. Study was conducted using qualitative design and working group was composed of a total of 121 teacher candidates (62 females and 59 males) attending Social Studies Teaching Department of Karadeniz Technical University and Adiyaman University…

  6. A Data-Driven Voter Guide for U.S. Elections: Adapting Quantitative Measures of the Preferences and Priorities of Political Elites to Help Voters Learn About Candidates

    Directory of Open Access Journals (Sweden)

    Adam Bonica

    2016-11-01

    Full Text Available Internet-based voter advice applications have experienced tremendous growth across Europe in recent years but have yet to be widely adopted in the United States. By comparison, the candidate-centered U.S. electoral system, which routinely requires voters to consider dozens of candidates across a dizzying array of local, state, and federal offices each time they cast a ballot, introduces challenges of scale to the systematic provision of information. Only recently have methodological advances combined with the rapid growth in publicly available data on candidates and their supporters to bring a comprehensive data-driven voter guide within reach. This paper introduces a set of newly developed software tools for collecting, disambiguating, and merging large amounts of data on candidates and other political elites. It then demonstrates how statistical methods developed by political scientists to measure the preferences and expressed priorities of politicians can be adapted to help voters learn about candidates.

  7. The Study of LGBT Politics and Its Contributions to Political Science

    Science.gov (United States)

    Mucciaroni, Gary

    2011-01-01

    Although the study of LGBT (lesbian, gay, bisexual, transgender) politics appears to be widely accepted within political science, a recent survey of political scientists reported some skepticism about its legitimacy and scholarly worth (Novkov and Barclay 2010). This article examines potential concerns about LGBT studies and draws attention to the…

  8. What Do Teacher Candidates Think about the Teaching Education? The Example of Social Studies Teacher Candidates

    Science.gov (United States)

    Tonga, Deniz

    2016-01-01

    In this research, it is aimed to reveal the opinions and observations of social studies teacher candidate about the courses they have taken during their 4-year university education. The focus group interview was used as the data collecting tool, and the content analyses were performed on the data obtained. The criterion sampling approach was used…

  9. Inside the Agenda-Setting Process: How Political Advertising and TV News Prime Viewers Think about Issues and Candidates.

    Science.gov (United States)

    Schleuder, Joan; And Others

    A study of the agenda-setting influence of the mass media on adult viewers explored (in a series of five experiments) how political knowledge stored in long term memory can be activated by the media, leading to decisions about issue salience. Spreading activation theory formed the basis for the study, and priming--the concept that the activation…

  10. ‘Don’t Leave Before You Understand’: Supporting Master’s Candidates in Business Studies

    Directory of Open Access Journals (Sweden)

    Christine Winberg

    2015-06-01

    Full Text Available Postgraduate studies in business faculties pose particular challenges to candidates who have come from practically-oriented undergraduate programmes, particularly those that adopt a ‘technical-rational’ approach towards the improvement of business practices or organisational efficiency. Research studies in the applied business fields usually expect that the candidate will take a more sociological approach, or be able to work within socio-historical or political frameworks (Hordern, 2014. Candidates who are enrolled for postgraduate business studies have to negotiate this complex transition. The focus of this paper is how candidates acquire the necessary academic and social practices for theorising their research, for conducting research activities and writing up their research findings in Masters level applied business studies. We selected candidates who had experienced difficulties throughout their Masters studies and who had successfully completed, or who were close to completion, despite initial difficulty for narrative interviews. The interview data were analysed with a view to establishing the practices that supported successful transition from practice-based undergraduate business degrees to postgraduate studies in the field. This paper concludes with suggestions for supervisory practices that have the potential to support successful postgraduate research in applied business studies.

  11. Typology of electoral candidates. Case study: Sorin Oprescu

    Directory of Open Access Journals (Sweden)

    Coman, C.

    2011-01-01

    Full Text Available By applying the content analysis technique of communication andby using analysis patterns such as the theory of rational choices, thedramaturgical model, the attraction model, the transactional analysis, this study identifies 4 typical categories of candidates to Romania’s presidency(elitist, dominating, reactive, sociable. In the analysis of the electoral itinerary of candidate Sorin Oprescu there are considered aspects such as identity, symbolism, volunteering, propagandas and media exposure, in order to make a SWOT analysis, thus facilitating the understanding of the candidate failure within the election process.

  12. COMPOSITIONAL AND CONTENT-RELATED PARTICULARITIES OF POLITICAL MEDIA TEXTS (THROUGH THE EXAMPLE OF THE TEXTS OF POLITICAL VIDEO CLIPS ISSUED BY THE CANDIDATES FOR PRESIDENCY IN FRANCE IN 2017

    Directory of Open Access Journals (Sweden)

    Dmitrieva, A.V.

    2017-09-01

    Full Text Available The article examines the texts of political advertising video clips issued by the candidates for presidency in France during the campaign before the first round of elections in 2017. The mentioned examples of media texts are analysed from the compositional point of view as well as from that of the content particularities which are directly connected to the text structure. In general, the majority of the studied clips have a similar structure and consist of three parts: introduction, main part and conclusion. However, as a result of the research, a range of advantages marking well-structured videos was revealed. These include: addressing the voters and stating the speech topic clearly at the beginning of the clip, a relevant attention-grabbing opening phrase, consistency and clarity of the information presentation, appropriate use of additional video plots, conclusion at the end of the clip.

  13. Politicizing science: conceptions of politics in science and technology studies.

    Science.gov (United States)

    Brown, Mark B

    2015-02-01

    This essay examines five ideal-typical conceptions of politics in science and technology studies. Rather than evaluating these conceptions with reference to a single standard, the essay shows how different conceptions of politics serve distinct purposes: normative critique, two approaches to empirical description, and two views of democracy. I discuss each conception of politics with respect to how well it fulfills its apparent primary purpose, as well as its implications for the purpose of studying a key issue in contemporary democratic societies: the politicization of science. In this respect, the essay goes beyond classifying different conceptions of politics and also recommends the fifth conception as especially conducive to understanding and shaping the processes whereby science becomes a site or object of political activity. The essay also employs several analytical distinctions to help clarify the differences among conceptions of politics: between science as 'political' (adjective) and science as a site of 'politics' (noun), between spatial-conceptions and activity-conceptions of politics, between latent conflicts and actual conflicts, and between politics and power. The essay also makes the methodological argument that the politics of science and technology is best studied with concepts and methods that facilitate dialogue between actors and analysts. The main goal, however, is not to defend a particular view of politics, but to promote conversation on the conceptions of politics that animate research in social studies of science and technology.

  14. Study of candidate genes for dyslexia in Brazilian individuals.

    Science.gov (United States)

    Svidnicki, M C C M; Salgado, C A; Lima, R F; Ciasca, S M; Secolin, R; Pomilio, M C A; Junqueira, P A; Pinto, M S; Pereira, M M; Sartorato, E L

    2013-11-07

    Dyslexia or reading disability (RD) is the most common childhood learning disorder and a significantly heritable trait. Many recent studies have investigated the genetic basis of dyslexia, and several candidate genes have been proposed. Among these, DCDC2 and KIAA0319 have emerged as the strongest candidate genes for dyslexia; however studies have not provided uniformly supportive results. The aim of this study was to assess the contribution of proposed candidate genes to the molecular etiology of dyslexia in a Brazilian sample. Large deletions and duplications in the candidate genes DCDC2, KIAA0319, and ROBO1 were investigated in 51 dyslexic subjects. Furthermore, a family-based association study was performed to investigate whether associations observed in other populations with variants in the DCDC2 and KIAA0319 genes were reproducible in Brazilian dyslexic individuals. Our analysis did not detect any deletions or duplications in the genes studied, and we found no evidence that the allelic variants in the two candidate genes were significantly associated with RD in our sample. Our data do not support a role of the DCDC2/KIAA0319 locus in influencing dyslexia as a categorical trait. Given the genetic complexity of dyslexia, it is plausible that both genes contribute to an increased risk, but the relative influence of these 2 genes on RD varies in different study samples, and/or depends on analytical approaches.

  15. Politeness

    Directory of Open Access Journals (Sweden)

    Henri Bergson

    2016-12-01

    Full Text Available This is the English translation of a speech Bergson made at Lycée Henri-IV on July 30, 1892. This is an interesting text because it anticipates Bergson’s last book, his The Two Sources of Morality and Religion. Like the distinction in The Two Sources between the open and the closed, “Politeness” defines its subject matter in two ways. There is what Bergson calls “manners” and there is true politeness. For Bergson, both kinds of politeness concern equality. Manners or material politeness amount to the ritualized greetings and formalities by means of which we usually define politeness. Unfortunately and like The Two Sources, Bergson attributes this formalized relation to other human beings with primitive and “inferior races.” Nevertheless, Bergson sees in these formalities an attempt, in the name of equality, to ignore other people’s talents and merits so that one can dominate morally superior people. In contrast, true politeness or “spiritual politeness” consists in “intellectual flexibility.” When one meets a person of superior morality, one is flexible in one’s relation to him or her; one abandons the formalities in order to really live her life and think her thoughts. Here we find equality too: “what defines this very polite person is to prefer each of his friends over the others, and to succeed in this way in loving them equally.” After making a comparison to dance, Bergson defines spiritual politeness as “a grace of the mind.” Since both kinds of politeness concern equality, Bergson associates both with justice. However, beyond these two kinds of politeness and justice there is “politeness of the heart,” which concerns charity. In order to indicate politeness of the heart, Bergson describes the kind of person, a sensitive person, who anxiously awaits a word of praise in order to feel good about herself but who also, when she hears a word of reproach, is thrown into sadness. Although Bergson calls the

  16. Political Economies of Health: A Consideration for International Nursing Studies

    Science.gov (United States)

    Peters, Michael A.; Drummond, John S.

    2008-01-01

    This article introduces and explores the concept of political economy. In particular it focuses upon the political economy of health while also considering the implications for international nursing studies in the context of health care more generally. Political economy is not only about budgets, resources and policy. It is also about particular…

  17. A Pragmatic Study of Barak Obama's Political Propaganda

    Science.gov (United States)

    Al-Ameedi, Riyadh Tariq Kadhim; Khudhier, Zina Abdul Hussein

    2015-01-01

    This study investigates, pragmatically, the language of five electoral political propaganda texts delivered by Barak Obama. It attempts to achieve the following aims: (1) identifying the speech acts used in political propaganda, (2) showing how politicians utilize Grice's maxims and the politeness principle in issuing their propaganda, (3)…

  18. Party and candidate websites: A comparative explanatory analysis

    NARCIS (Netherlands)

    Kruikemeier, S.; Aparaschivei, A.P.; Boomgaarden, H.G.; van Noort, G.; Vliegenthart, R.

    2015-01-01

    This study provides a systematic investigation of party and candidate websites across five countries. It examines three prominent features of current online political communication (interactivity, political personalization, and mobilization). Furthermore it assesses to what extent country, party,

  19. Online politics: a cross-national explanatory analysis of political websites

    NARCIS (Netherlands)

    van Noort, G.; Kruikemeier, S.; Aparaschivei, A.; Boomgaarden, H.; Vliegenthart, R.

    2013-01-01

    This study provides a systematic investigation of party and candidate websites in five European countries: Germany, Romania, Hungary, The Netherlands and Great Britain. It examines three features of online political communication that are presented on political websites (interactivity,

  20. Case Study: "Care" as a Political Winner

    Directory of Open Access Journals (Sweden)

    Meredith Loomis Quinlan

    2017-03-01

    Full Text Available Through face-to-face conversations and open-ended questions designed to elicit stories and deeper interactions, the Michigan People’s Campaign (MPC may have altered voting patterns more effectively than using traditional electoral engagement strategies. During the 2016 election, by campaigning on issues of family care, MPC helped elect a progressive state house candidate in a Downriver Detroit district that Republican presidential candidate Donald Trump carried by over 6,000 votes.

  1. Integrating Women into the Study of Politics.

    Science.gov (United States)

    Elison, Sonja

    1997-01-01

    Maintains that participatory classroom exercises can enrich students' perception of the importance of gender as a concept in political science. Describes three exercises that integrate the concept of gender into the examination of electoral systems, social movements, and German unification. Discusses student response to this approach. (MJP)

  2. Facebook, Political Narrative, and Political Change: A Case Study of Palestinian Youth

    OpenAIRE

    Kenderes, Amanda

    2012-01-01

    In this dissertation I aim to advance political narrative theory by exploring the use of political narrative on Facebook and the possibility for Facebook to be used among Palestinian youth for political change. To examine the concepts of political narrative and political change, I developed a model for political change based on the changing political narratives which in part prompted the 2011 Egyptian revolution. The model, Political Narrative Perspectives (PNPs), identifies individual and re...

  3. Neuropolitics: EEG spectral maps related to a political vote based on the first impression of the candidate's face.

    Science.gov (United States)

    Vecchiato, G; Toppi, J; Cincotti, F; Astolfi, L; De Vico Fallani, F; Aloise, F; Mattia, D; Bocale, S; Vernucci, F; Babiloni, F

    2010-01-01

    The aim of the present research is to investigate the EEG activity elicited by a fast observation of face of real politicians during a simulated political election. Politician's face are taken from real local election performed in Italy in the 2004 and 2008. We recorded the EEG activity of eight healthy subjects while they are asked to give a judgment on dominance, trustworthiness traits and a preference of vote on faces shown. Statistical differences of spectral EEG scalp activity have been mapped onto a realistic head model. For each experimental condition, we employed the t-test to compare the PSD values and adopted the False Discovery Rate correction for multiple comparisons. The scalp statistical maps revealed a desynchronization in the alpha band related to the politicians who lost the simulated elections and have been judged less trustworthy. Although these results might be congruent with the recent literature, the present is the first EEG study about and there is the need to extend the paradigm and the analysis on a larger number of subjects to validate these results.

  4. A study on the impact of campaign finance, political capital and gender on electoral performance

    Directory of Open Access Journals (Sweden)

    Bruno Wilhelm Speck

    2014-04-01

    Full Text Available This article analyzes the association between political finance and electoral performance in the 2010 Brazilian elections for state and federal deputies. It also investigates the interaction effect of incumbency and gender on this association. We conclude: (i there is a positive and statistically significant association between political finance and electoral performance, yet the intensity of this association varies according to the type of candidate; (ii the association is stronger for challengers than for incumbents – thus extending the "Jacobson effect" to the Brazilian case; and (iii the association is stronger for women than for men – which suggests an extension of the idea underlying the "Jacobson effect". The association between finance and electoral performance tends to be stronger for candidates facing electoral disadvantages, whether these stem from limited political capital, gender discrimination, or any other factor not studied here resulting in a similar effect. Political finance works as a tool that, to some extent, may counteract the negative effect of such factors on electoral performance.

  5. Does Studying Political Science Affect Civic Attitudes?: A Panel Comparison of Students of Politics, Law, and Mass Communication

    Science.gov (United States)

    Esaiasson, Peter; Persson, Mikael

    2014-01-01

    The article evaluates the civic implications of studying political science. Previous research has argued that learning rational choice models of political behavior could be detrimental to civic outcomes. However, results from our two panel surveys of students at Swedish universities show the opposite: studying political science has positive…

  6. The specific of the romanian political language in the second half of XIX century. Case study: Mihai Eminescu's political articles

    OpenAIRE

    Mocanu, Mihaela

    2017-01-01

    Abstract Our study proposes an analysis of Romanian political language in the second half of XIX century, in terms of specific discursive mechanisms, of semantic mutations that are recorded in the political vocabulary of the time, of the discrepancies that characterize verbal sign in the space of political communication. Since the press of this time plays a crucial role in the formation and distribution of the Romanian political language, we support our observations on the analysis of pol...

  7. Study of Self-Efficacy Perceptions of Social Studies Teacher Candidates on Educational Internet Usage

    Science.gov (United States)

    Akman, Özkan

    2016-01-01

    This study aimed at examining the self-efficacy perceptions of social studies teacher candidates with respect to educational internet use. This research was conducted on a sample of 174 social studies teacher candidates enrolled in Gaziantep University Nizip Faculty of Education. The "Educational Internet Self-Efficacy Scale," developed…

  8. Perceived Justice in Political Marketing: An Exploratory Study

    Directory of Open Access Journals (Sweden)

    Ihwan Susila

    2011-06-01

    Full Text Available The purpose of this study is to criticize and develop the construct of equity theory within the framework of perceived justice. Specifically, this study aims to investigate perceived justice construct in political marketing perspective. Sample of the research consist of voters of political parties in Indonesia.Data were collected through interviews and a survey using a structured questionnaire with a purposive sampling method to 150 respondents. The study use exploratory factor analyses and Cronbach Alpha method to test the construct validity. The research also use measurement model of structural equation model (SEM which is the same as confirmatory factor analysis procedure. Qualitative method also used in this research to investigate the new construct of perceived justice in political marketing. Result of the study found that procedural justice has weak construct validity and the definition of the construct is not clear. Findings the new concept of justice in a political marketing perspective discussed in this article.

  9. Political Cults as a New Phenomenon of Religious Studies

    Directory of Open Access Journals (Sweden)

    Zoya Vladimirovna Silayeva

    2017-09-01

    Full Text Available The article investigates the study of political cults, the emergence of which is the result of ongoing processes in the religious sphere in the post-secular period. These processes include the active formation and development of new religious movements and politicization of the religion. The growth of their influence is due to a number of reasons. Firstly, the post-Soviet period was characterized by a crisis of religious and national identity, which facilitated the growth of people's interest in the non-traditional religiosity. Secondly, there was an increase in the desire of religious groups to participate in the political process by any means in the 90s. As a result, such processes generate a controversial phenomenon of "political cult". This article includes an attempt to consider and analyze the approaches to the definition of the "political cult" concept available in the current literature. To this end, we have chosen a systematic approach that enables, considering the constructivist and instrumental features of this phenomenon, to consider it from the point of view of a structural, functional and strategic model. This approach made it possible to identify specific features of the political cult, distinguishing it from political parties and individual religious-political entities.

  10. Situating Poligen Studies: Between Moral Enquiry and Political Theory

    Directory of Open Access Journals (Sweden)

    Réal Fillion

    2017-12-01

    Full Text Available In this article, I argue that we can best appreciate those works that appeal to the notion of “political genealogy” as distinct forms of study by situating them between moral enquiry and political theory. They draw from moral enquiry the concern with how we ought to live but are not themselves prescriptive. They address the political constitution of our social lives but not as a theoretical object. Reversing the relation between enquiry and truth, political genealogies are historiographical studies motivated by forms of resistance that expose the will to truth of the present ordering of discourses, thereby releasing the hold such orderings have on what we think, say, and do to their on-going agonistic relations.

  11. PROSPECTS OF DEVELOPMENT OF POLITICAL IMAGEOLOGY

    Directory of Open Access Journals (Sweden)

    Tatiana Evgenievna Telyatnik

    2016-04-01

    Practical implications: results of the conducted research can be used in the applied directions of political science, in studying and the analysis of political image; in the course of designing of image of the political leader or the candidate in election campaign.

  12. Political Consciousness but Not Political Engagement: Results from a Service-Learning Study

    Science.gov (United States)

    Harker, Dave

    2016-01-01

    How does participation in a service-learning program impact the way students think about politics and political engagement? There are reasons to expect that service-learning can contribute to the development of a political consciousness and the skills necessary for political participation. The author uses participant observation, in-depth…

  13. Digital Trace Data in the Study of Public Opinion : An Indicator of Attention Toward Politics Rather Than Political Support

    OpenAIRE

    Jungherr, Andreas; Schoen, Harald; Posegga, Oliver; Jürgens, Pascal

    2017-01-01

    In this article, we examine the relationship between metrics documenting politics-related Twitter activity with election results and trends in opinion polls. Various studies have proposed the possibility of inferring public opinion based on digital trace data collected on Twitter and even the possibility to predict election results based on aggregates of mentions of political actors. Yet, a systematic attempt at a validation of Twitter as an indicator for political support is lacking. In this...

  14. Islamist Women and Political Rights : A Case Study of Islamist Women's Increasing Political Participation in Egypt's Muslim Brotherhood.

    OpenAIRE

    Lillevik, Ragna

    2012-01-01

    Islamist women have become increasingly visible in politics in Egypt over the last decade. What can explain their increased political participation? This thesis examines women's participation in a case study of the Egyptian Muslim Brotherhood. I do so by the use of qualitative interviews with Islamist women in Cairo as well as an extensive review of previous research. In doing so, the relationship between Islamism and the development of women's political rights is explored. The empirical evid...

  15. Politics, Film Studies, and the Academy: A Commentary.

    Science.gov (United States)

    Worland, Rick

    1995-01-01

    Discusses two related topics affecting film studies as an institution: questions concerning certain paradigms of contemporary theory (poststructuralism in particular) as they relate to politics; and to a greater extent, the relationship of this latter issue to the institutionalization of film studies in the academy. (SR)

  16. Political Correctness and Political Science: An Exploratory Study of New York State.

    Science.gov (United States)

    Harman, John D.; Bowers, James R.

    1994-01-01

    Maintains that the issue of political correctness has gained wide coverage in the press as it relates to higher education academic policy. Reports on a survey of 196 New York State political scientists. Finds that they perceive political correctness as an issue on their college campus and in the discipline, but not in their departments. (CFR)

  17. Intimacy’s Politics: New Directions in Caribbean Sexuality Studies

    Directory of Open Access Journals (Sweden)

    Vanessa Agard-Jones

    2011-12-01

    Full Text Available Review of: Pleasures and Perils: Girls’ Sexuality in a Caribbean Consumer Culture. Debra Curtis. New Brunswick NJ: Rutgers University Press, 2009. xii + 222 pp. (Paper US$ 23.95 Economies of Desire: Sex and Tourism in Cuba and the Dominican Republic. Amalia L. Cabezas. Philadelphia PA : Temple University Press, 2009. xii + 218 pp. (Paper US$ 24.95 Queer Ricans: Cultures and Sexualities in the Diaspora. Lawrence La Fountain-Stokes. Minneapolis: University of Minnesota Press, 2009. xxvii + 242 pp. (Paper US$ 22.50 [First paragraph] Over the last ten years the field of Caribbean Studies has seen a precipitous expansion of work on sexualities, as recent review essays by Jenny Sharpe and Samantha Pinto (2006 and Kamala Kempadoo (2009 have observed. The three books under review here, all based on dissertation research and all published in 2009, make important contributions to this growing literature. While each one approaches sexual politics from a distinctive disciplinary, geographic, and theoretical vantage point, all three ask readers to take seriously the central place that sexual desires and practices occupy in the lives of Caribbean people, both at home and in the diaspora. Caribbean sexuality studies are still sometimes thought of as belonging to a domain outside of, or auxiliary to “real” politics, but these studies demonstrate without hesitation how sexuality functions as an important prism through which we might understand broader debates about ethics, politics, and economics in the region. Building from the insights of feminist theorists who connect the “private” realm to community, national, and global geopolitics, they show that sex is intimately connected to certain freedoms – be they market, corporeal, or political – as well as to their consequences. Taken together, they consider sexual subjectivity, political economy, and cultural production in unexpected ways and point to exciting new directions for the

  18. Indigenous Studies and the Politics of Language

    Science.gov (United States)

    McGloin, Colleen; Carlson, Bronwyn L.

    2013-01-01

    Language use changes over time. In Indigenous contexts, language alters to suit the shifting nature of cultural expression as this might fit with Indigenous peoples' preference or as a consequence of changes to outdated and colonial modes of expression. For students studying in the discipline of Indigenous Studies, learning to use appropriate…

  19. Political Campaigns

    OpenAIRE

    Lilleker, Darren

    2017-01-01

    Political campaigns are orchestrated attempts by political organizations to garner public support through persuasive communication in order to influence public policy in their favor. This broad definition encapsulates all forms of campaigns from those of neighborhood organizations seeking to influence local politicians to the campaigns of political parties and candidates who seek election to office in order to shape policy themselves. In pluralist democracies, campaigns are crucial for repres...

  20. Candidate genes detected in transcriptome studies are strongly dependent on genetic background.

    Directory of Open Access Journals (Sweden)

    Pernille Sarup

    2011-01-01

    Full Text Available Whole genome transcriptomic studies can point to potential candidate genes for organismal traits. However, the importance of potential candidates is rarely followed up through functional studies and/or by comparing results across independent studies. We have analysed the overlap of candidate genes identified from studies of gene expression in Drosophila melanogaster using similar technical platforms. We found little overlap across studies between putative candidate genes for the same traits in the same sex. Instead there was a high degree of overlap between different traits and sexes within the same genetic backgrounds. Putative candidates found using transcriptomics therefore appear very sensitive to genetic background and this can mask or override effects of treatments. The functional importance of putative candidate genes emerging from transcriptome studies needs to be validated through additional experiments and in future studies we suggest a focus on the genes, networks and pathways affecting traits in a consistent manner across backgrounds.

  1. Management Studies Educational Knowledge: Technical, Elite or Political?

    Science.gov (United States)

    Hordern, Jim

    2014-01-01

    This paper draws on the technical, elite and political interpretations of the purpose of management, to identify demands for particular forms of educational knowledge in the management studies curriculum. The varied character of this knowledge is discussed using Bernsteinian concepts of verticality, grammaticality, classification and framing, and…

  2. Political discourse as social actions: A study of selected campaign ...

    African Journals Online (AJOL)

    Linguistic and discourse approaches are adopted to describe how campaign utterances constitute discourse acts. Insights from the Speech Act Theory (Austin, 1962 and Searle, 1969) provide the theoretical standpoint, from which the essay describes political campaign utterances as social actions. The data set for the study ...

  3. Contributions of Print Journalism to the Study of Political Communication.

    Science.gov (United States)

    Garrison, Bruce

    Print journalism and journalism research have contributed many concepts, principles, and communication techniques to the field of political communication. An examination of the indexes of "Public Opinion Quarterly,""Journalism Quarterly," and the "Journal of Communication" through the mid-1960s indicates the evolution of the study of print media…

  4. Studies of some IAEA candidate reference materials for microanalytical techniques

    International Nuclear Information System (INIS)

    Zhang Yuanxun; Qian Yine; Li Deyi; Wang Yinsong; Tan Mingguang; Wang Xuepeng; Gu Yingmei; Zhu Jieqing

    2002-01-01

    In order to develop new reference materials for microanalytical nuclear techniques, the Scanning Proton Microprobe (SPM) technique was used to determine homogeneity level within 100x200 μm 2 micro-area on the small pieces of IAEA Urban Dust reference materials. In part 1 of this paper, the experimental methods are described in detail. The results show that IAEA-396A/M Vienna Urban Dust is homogeneous enough for small sample analysis. As a task we prepared the IAEA-386 bovine liver as a new candidate reference material to meet this purpose. In part 2, the preparation process including material collection, dried, pulverize, sieve, homogenization and preliminary test is described in detail. The more effective grinding methods were established to achieve the median particle size of 22 μm. Also in part.3 we performed the qualitative determinations of some candidate reference materials by NAA and AFS. (author)

  5. Personal values and political activism: a cross-national study.

    Science.gov (United States)

    Vecchione, Michele; Schwartz, Shalom H; Caprara, Gian Vittorio; Schoen, Harald; Cieciuch, Jan; Silvester, Jo; Bain, Paul; Bianchi, Gabriel; Kirmanoglu, Hasan; Baslevent, Cem; Mamali, Catalin; Manzi, Jorge; Pavlopoulos, Vassilis; Posnova, Tetyana; Torres, Claudio; Verkasalo, Markku; Lönnqvist, Jan-Erik; Vondráková, Eva; Welzel, Christian; Alessandri, Guido

    2015-02-01

    Using data from 28 countries in four continents, the present research addresses the question of how basic values may account for political activism. Study 1 (N = 35,116) analyses data from representative samples in 20 countries that responded to the 21-item version of the Portrait Values Questionnaire (PVQ-21) in the European Social Survey. Study 2 (N = 7,773) analyses data from adult samples in six of the same countries (Finland, Germany, Greece, Israel, Poland, and United Kingdom) and eight other countries (Australia, Brazil, Chile, Italy, Slovakia, Turkey, Ukraine, and United States) that completed the full 40-item PVQ. Across both studies, political activism relates positively to self-transcendence and openness to change values, especially to universalism and autonomy of thought, a subtype of self-direction. Political activism relates negatively to conservation values, especially to conformity and personal security. National differences in the strength of the associations between individual values and political activism are linked to level of democratization. © 2014 The British Psychological Society.

  6. Affect in electoral politics.

    Science.gov (United States)

    Glaser, J; Salovey, P

    1998-01-01

    Recent U.S. history provides vivid illustrations of the importance of politicians' emotional displays in subsequent judgments of them. Yet, a review of empirical research on the role of affect (emotion, mood, and evaluation) in electoral politics reveals little work that has focused on the impact of candidates' emotional expression on voters' preferences for them. A theoretical framework is proposed to identify psychological mechanisms by which a target's displays of emotion influence judgments of that target. Findings from the emerging literature on emotions and politics challenge the traditional assumption of political science that voters make decisions based solely on the cold consideration of nonaffectively charged information. The affect and politics literature, although somewhat unfocused and broad, represents an interdisciplinary domain of study that contributes to the understanding of both electoral politics and social interaction more generally.

  7. Meaning That Social Studies Teacher Candidates Give to Value Concept and Their Value Rankings

    Science.gov (United States)

    Aysegül, Tural

    2018-01-01

    This work determines the role that value education plays in shaping people's personal and social life. This research aims to put forward meaning that social studies teacher candidates give to value concept and its value ranking. To achieve this aim, the opinions of 12 social studies teacher candidates were obtained. During the data collection…

  8. Politeness in Brazil and Spain: a comparative case study

    Directory of Open Access Journals (Sweden)

    Enrique Huelva Unterbäumen

    2011-12-01

    Full Text Available The aim of this paper is to present some results of a comparative study between the politeness strategies that two Spanish and two Brazilian professors would use, both in Portuguese and Spanish, in twelve hypothetical situations presented on a social behavior questionnaire. This work is based on a previous study published by Piatti (2003 in Argentina, where the author observed some pragmatic differences between a group of students of Spanish as a foreign language and a group of native speakers of the language. With her hypotheses as a starting point, the scope was moved to a small group of people with high communicative competence in both languages, in order to give a different insight on of the pragmatic differences that exist between Brazilians and the Spanish. Based on the findings, we have tried to establish some intercultural differences among the politeness strategies used in Brazil and in Spain.

  9. A Critical Study of Selected Political Elites' Discourse in English

    Directory of Open Access Journals (Sweden)

    Biook Behnam

    2008-02-01

    Full Text Available This study explored how political elites can contribute to power enactment through using language. It started with a theoretical overview of Critical Discourse Analysis (CDA, and then presented a corpus consisting of speeches of eight political elites, namely, Malcolm X, Noam Chomsky, Martin Luther King, Josef Stalin, Vladimir Lenin, Winston Churchill, J.F. Kennedy and Adolph Hitler. This study analyzed speeches in terms of figures of' speech, and interpreted them from the point of view of CDA using the framework introduced by Fairclough (1989 as a three-dimensional approach to the study of discourse (Description, Interpretation, Explanation and van Dijk (2004 as the theory of critical context analysis.. Speech figures are classified in this study into six main categories as Comparison, Grammar, Meaning, Parenthesis, Repetition and Rhetoric. The result of analyses reveals that while there are differences in the type and degree of speech figures employed by our selected individual political elites, there is one striking pattern which is common among all speeches: the frequent use of figures of Grammar, Repetition and Rhetoric

  10. Inoculation in Political Campaign Communication.

    Science.gov (United States)

    Pfau, Michael; Burgoon, Michael

    1988-01-01

    Posits a strategy of resistance to the influence of attack messages in political campaigns. Finds that political campaign messages can be designed to inoculate supporters of candidates against subsequent attack messages of opposing candidates. (MS)

  11. Studying the Russian Arctic: the experience of political analysis

    Directory of Open Access Journals (Sweden)

    Dmitry P. Kondral

    2016-12-01

    Full Text Available The authors discuss the main directions of the political science study of the issues of development of northern regions of the country, the theoretical and applied research in the field of strategic management processes of spatial and territorial development of the North and the Russian Arctic. Key areas of political studies on the management of these processes are systematized and summarized, the main external and internal issues of the Arctic and subarctic regions of the country are analized, connected with the quality of the political process control systems of their spatial and social development. The mechanisms of accounting of interests of key actors in the North of Russia are investigated, recommendations for improving process of control mechanisms of spatial and social development of the northern regions of the country are given. The researchers specify the development of a new paradigm of considering the North and the Russian Arctic, involving the recognition of the value of the northern territories, not only as a resource base of the country, but mostly as social formations.

  12. Study on candidate gene for fecundity traits in Xingjiang Cele black ...

    African Journals Online (AJOL)

    The aim of the present study is to find a potential candidate gene for high fecundity in Cele black sheep. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) technology was used to detect single nuclear polymorphism (SNP) of four candidate genes (BMPR-IB, BMP15, GDF9, and ESRα) in Cele ...

  13. A Case Study of White Teacher Candidates' Conceptions of Racial Profiling in Educational Contexts

    Science.gov (United States)

    Baggett, Hannah Carson; Simmons, Crystal G.

    2017-01-01

    This qualitative case study explored how two White teacher candidates understood and conceptualized racial profiling in the wake of Trayvon Martin's murder. The teacher candidates were interviewed about their experiences with profiling in educational contexts. One participant conceptualized racial profiling as intrinsic to her understanding of the…

  14. An Appraisal of the Utilisation of Social Media for Political ...

    African Journals Online (AJOL)

    Prof

    Ho 1: Voter's choice of political candidates in the 2011 presidential election was not influenced by political communication on ... Ho 3: Electorate voting pattern during the 2011 elections was not influenced by their exposure to political messages on social ...... Studies.1 (2), 161- 173. Sherman, A. (2010). The problem with ...

  15. Political Communication in Malaysia: A study on the Use of New Media in Politics

    OpenAIRE

    Pauline Pooi Yin Leong

    2015-01-01

    To gain and retain political power, politicians use the media to persuade the masses to vote and support them, especially during elections. Barisan Nasional (BN) has successfully used the media to maintain its power for the past 57 years, making it the longest-serving elected government in the world still currently in office. However, the emergence of the Internet has challenged the status quo. The purpose of the research was to investigate how new media has influenced the political process a...

  16. 4 CFR 7.3 - Political activities.

    Science.gov (United States)

    2010-01-01

    ... not take an active part in political management or in a political campaign, except as permitted by... political campaign of a candidate for public office in a partisan election or a candidate for political... political party office in a political advertisement, a broadcast, campaign, literature, or similar material...

  17. Building community in international politics: A study of political press conferences

    Directory of Open Access Journals (Sweden)

    Aditi Bhatia

    2011-04-01

    Full Text Available In today’s increasingly globalised yet disconnected world, especially in the contemporary context of a turbulent political landscape, there has been an increasing effort made by socio-political leaders at solidifying alliances and drawing support from different corners of the world in order to neutralize policies. Drawing on a multidimensional framework, in particular, critical discourse analysis and membership categorization analysis, this paper explores the various strategies employed by political leaders, attempting to reconcile disparate perspectives in the face of increasing socio-economic inter-connection and political dependence. More often than not, it was discovered, political leaders drew upon the somewhat “illusory” notion of “international community”, turning it into a tool of persuasion and membership category. In doing so, this paper aims to illustrate how the creation of illusive categories and perceptions are intended as a means of drawing support from diverse political leaders and projecting a united front before scrutinizing press and public.

  18. Images of Famous People in Political Advertising: Youth Perceptions and Position

    OpenAIRE

    Liubov I. Ryumshina

    2013-01-01

    The article touches upon the issues of youth awareness about the recent political events and its attitude to the political advertising, examines youth perception and position in respect of famous people, as well as candidates participation in political advertising on the example of the last presidential campaign. The study describes the most attractive elements of the political advertising for youth

  19. Determinants of Political Violence: A Study of the Literature

    OpenAIRE

    Daniel Mider

    2014-01-01

    Political violence is a complex phenomenon that is induced by numerous factors. The article focuses on trying to identify and organize the sources of political violence. Three groups of determinants of political violence can be distinguished on the basis of the examined social science literature. The first group of determinants of political violence ¨C referred to as structural determinants ¨C is examined by researchers within the social structure. Cultural patterns and norms operating within...

  20. POLITICAL CORRUPTION: AN INTRODUCTORY STUDY ON TERMINOLOGY AND TYPOLOGY

    OpenAIRE

    Aktan, Coşkun Can

    2018-01-01

    The concept of corruption is generally used to mean all actions and behaviors constituting bribery, embezzlement, favoritism etc. It is important to note that, “corruption” is the name given to the certain types of corruption (mainly; bribery, embezzlement, favoritism), which has political characteristics. Political corruption has a wider meaning than corruption. In other words, political corruption is an umbrella concept which also includes corruption. This paper explores political corruptio...

  1. Political and legal approach to contemporary local democracies collisions` studies

    Directory of Open Access Journals (Sweden)

    K. M. Burya

    2017-04-01

    It has been underlined that heuristic potential of political and legal approach in political science research is based on the possibility to solve genuine issues that contain the means of the legal provision of political institutions and the impact of these institutions on the normative context.

  2. Political Communication in Malaysia: A study on the Use of New Media in Politics

    Directory of Open Access Journals (Sweden)

    Pauline Pooi Yin Leong

    2015-10-01

    Full Text Available To gain and retain political power, politicians use the media to persuade the masses to vote and support them, especially during elections. Barisan Nasional (BN has successfully used the media to maintain its power for the past 57 years, making it the longest-serving elected government in the world still currently in office. However, the emergence of the Internet has challenged the status quo. The purpose of the research was to investigate how new media has influenced the political process and communication strategies in Malaysia and its impact on the political landscape. The researcher interviewed 19 respondents: politicians, bloggers and media consultants from both sides of the political divide. The findings showed that new media, especially Web 2.0, has expanded the public sphere and enabled more Malaysians to participate in the democratic process, through information dissemination, mobilisation or crowd-sourcing. However, the cyber-war between BN and the opposition Pakatan Rakyat (PR has caused confusion and disinformation, affecting the quality of democratic decision-making. Nevertheless, new media has enabled more voices to emerge and challenge the political hegemony.

  3. Criticising with Foucault: Towards a Guiding Framework for Socio-Political Studies in Mathematics Education

    Science.gov (United States)

    Kollosche, David

    2016-01-01

    Socio-political studies in mathematics education often touch complex fields of interaction between education, mathematics and the political. In this paper I present a Foucault-based framework for socio-political studies in mathematics education which may guide research in that area. In order to show the potential of such a framework, I discuss the…

  4. Economic Literacy Levels of Social Studies Teacher Candidates

    Science.gov (United States)

    Akhan, Nadire Emel

    2015-01-01

    The purpose of this study is to determine the levels of economic literacy--an important component of being a good citizen--among seniors studying at social studies teacher program which aims at cultivating good citizens and to find out its relationships in terms of various variables. The quantitative sample of the study was comprised of 726 senior…

  5. Candidal infection in oral leukoplakia: a clinicopathologic study of 396 patients from eastern China.

    Science.gov (United States)

    Wu, Lan; Feng, Jinqiu; Shi, Linjun; Shen, Xuemin; Liu, Wei; Zhou, Zengtong

    2013-02-01

    Previous studies have suggested a link between the presence of Candida invasion and oral premalignant lesion. The objective of the current study was to investigate the clinicopathologic features of candidal infection in biopsies of a large retrospective cohort of patients with premalignant oral leukoplakia (n = 396) from eastern China and assess the clinical implications. Candidal hyphae were detected with periodic acid-Schiff staining of the biopsy samples. The results showed that 59 patients (15.9%) with oral leukoplakia were infected by Candida. The average age of the patients with candidal leukoplakia was 60.7 years with equal sex ratio. The tongue was the predominant site (66.1%). Epithelial hyperplasia and dysplasia were involved in 44.1% and 55.9% of patients, respectively. Multivariate analysis revealed that patient older than 60 years (odd ratio [OR], 2.28; P = .005), lesion located at the tongue (OR, 1.89; P = .038), and presence of dysplasia (OR, 2.02; P = .018) were significant risk factors of candidal infection in oral leukoplakia. Collectively, clinicopathologic features of candidal leukoplakia in eastern China were elucidated. A point to highlight was that we identified a subpopulation that was more liable to candidal infection. Elderly patients with oral tongue leukoplakia with epithelial dysplasia had much higher risk of candidal infection. Antifungal therapy was further recommended to be routine treatment of this subpopulation. Crown Copyright © 2013. Published by Elsevier Inc. All rights reserved.

  6. Advocacy and political convergence under preference uncertainty

    NARCIS (Netherlands)

    Reuben, E.; Traxler, C.; van Winden, F.

    2015-01-01

    We study the formation of advocacy groups and how they can impact policy outcomes by revealing information about voters׳ preferences to uninformed political candidates. We conduct a laboratory experiment based on a two-candidate spatial electoral competition setting where the policy preferences of

  7. Eating disorders: from twin studies to candidate genes and beyond

    NARCIS (Netherlands)

    Slof-Op 't Landt, M.C.T.; Furth, E.F. van; Meulenbelt, I.; Slagboom, P.E.; Bartels, M.; Boomsma, D.I.; Bulik, C.M.

    2005-01-01

    Substantial effort has been put into the exploration of the biological background of eating disorders, through family, twin and molecular genetic studies. Family studies have shown that anorexia (AN) and bulimia nervosa (BN) are strongly familial, and that familial etiologic factors appear to be

  8. Social Media Participation and Local Politics: A Case Study of the Enschede Council in the Netherlands

    NARCIS (Netherlands)

    Effing, R.; van Hillegersberg, Jos; Huibers, Theo W.C.; Wimmer, M.A.; Tambouris, E.; Macintosh, A.

    Social media such as Facebook, Twitter and YouTube are often seen as political game changers. Yet little is known of the effects of social media on local politics. In this paper the Social Media Participation Model (SMPM) is introduced for studying the effects of social media on local political

  9. Social Media Participation and Local Politics: A Case Study of the Enschede Council in the Netherlands

    NARCIS (Netherlands)

    Effing, Robin; van Hillegersberg, Jos; Huibers, Theo W.C.; Wimmer, Maria A.; Tambouris, Efthimios; Macintosh, Ann

    2013-01-01

    Social media such as Facebook, Twitter and YouTube are often seen as political game changers. Yet little is known of the effects of social media on local politics. In this paper the Social Media Participation Model (SMPM) is introduced for studying the effects of social media on local political

  10. Youtube and Political Communication Case study – Romanian’s Parliamentary Parties

    Directory of Open Access Journals (Sweden)

    Nicoleta Grasu

    2014-12-01

    Full Text Available The study aims at examining the extent to which the parliamentary parties in Romania use YouTube in order to promote the image and the political message of the certain political party as videos. This research is focused on the videos that can be seen on the official channels of the Social Democratic Party, of the National Liberal Party and of the Democratic Union of Hungarians in Romania. It will also be taken into consideration the grouping of the videos into categories such as: interviews, statements, public debates, official meetings, mass meetings of the party, press conferences and appearances in the media, leisure and electioneering. The research was limited by the fact that not all the parliamentary parties in Romania have an official Youtube channel and by the fact that two official channels work in the Social Media for about two years, although Romania is ranked 13th in the world among the countries with the highest download speed. This occurs in the context in which there is a Youtube channel in the United States, since 2007, where citizens were debating matters of public interest with the politician / candidate.

  11. Politics Perceptions as Moderator of the Political Skill-Job Performance Relationship: A Two-Study, Cross-National, Constructive Replication

    Science.gov (United States)

    Kapoutsis, Ilias; Papalexandris, Alexandros; Nikolopoulos, Andreas; Hochwarter, Wayne A.; Ferris, Gerald R.

    2011-01-01

    We developed a two-study, cross-national, constructive replication to examine the role of organizational politics perceptions as a contextual moderator of the political skill-job performance relationship. Specifically, we hypothesized that high levels of political skill would demonstrate its strongest positive effects on job performance when…

  12. Evaluating the ovarian cancer gonadotropin hypothesis: A candidate gene study

    Science.gov (United States)

    Lee, Alice W.; Tyrer, Jonathan P.; Doherty, Jennifer A.; Stram, Douglas A.; Kupryjanczyk, Jolanta; Dansonka-Mieszkowska, Agnieszka; Plisiecka-Halasa, Joanna; Spiewankiewicz, Beata; Myers, Emily J.; Chenevix-Trench, Georgia; Fasching, Peter A.; Beckmann, Matthias W.; Ekici, Arif B.; Hein, Alexander; Vergote, Ignace; Van Nieuwenhuysen, Els; Lambrechts, Diether; Wicklund, Kristine G.; Eilber, Ursula; Wang-Gohrke, Shan; Chang-Claude, Jenny; Rudolph, Anja; Sucheston-Campbell, Lara; Odunsi, Kunle; Moysich, Kirsten B.; Shvetsov, Yurii B.; Thompson, Pamela J.; Goodman, Marc T.; Wilkens, Lynne R.; Dörk, Thilo; Hillemanns, Peter; Dürst, Matthias; Runnebaum, Ingo B.; Bogdanova, Natalia; Pelttari, Liisa M.; Nevanlinna, Heli; Leminen, Arto; Edwards, Robert P.; Kelley, Joseph L.; Harter, Philipp; Schwaab, Ira; Heitz, Florian; du Bois, Andreas; Orsulic, Sandra; Lester, Jenny; Walsh, Christine; Karlan, Beth Y.; Hogdall, Estrid; Kjaer, Susanne K.; Jensen, Allan; Vierkant, Robert A.; Cunningham, Julie M.; Goode, Ellen L.; Fridley, Brooke L.; Southey, Melissa C.; Giles, Graham G.; Bruinsma, Fiona; Wu, Xifeng; Hildebrandt, Michelle A.T.; Lu, Karen; Liang, Dong; Bisogna, Maria; Levine, Douglas A.; Weber, Rachel Palmieri; Schildkraut, Joellen M.; Iversen, Edwin S.; Berchuck, Andrew; Terry, Kathryn L.; Cramer, Daniel W.; Tworoger, Shelley S.; Poole, Elizabeth M.; Olson, Sara H.; Orlow, Irene; Bandera, Elisa V.; Bjorge, Line; Tangen, Ingvild L.; Salvesen, Helga B.; Krakstad, Camilla; Massuger, Leon F.A.G.; Kiemeney, Lambertus A.; Aben, Katja K.H.; van Altena, Anne M.; Bean, Yukie; Pejovic, Tanja; Kellar, Melissa; Le, Nhu D.; Cook, Linda S.; Kelemen, Linda E.; Brooks-Wilson, Angela; Lubinski, Jan; Gronwald, Jacek; Cybulski, Cezary; Jakubowska, Anna; Wentzensen, Nicolas; Brinton, Louise A.; Lissowska, Jolanta; Yang, Hannah; Nedergaard, Lotte; Lundvall, Lene; Hogdall, Claus; Song, Honglin; Campbell, Ian G.; Eccles, Diana; Glasspool, Rosalind; Siddiqui, Nadeem; Carty, Karen; Paul, James; McNeish, Iain A.; Sieh, Weiva; McGuire, Valerie; Rothstein, Joseph H.; Whittemore, Alice S.; McLaughlin, John R.; Risch, Harvey A.; Phelan, Catherine M.; Anton-Culver, Hoda; Ziogas, Argyrios; Menon, Usha; Ramus, Susan J.; Gentry-Maharaj, Aleksandra; Harrington, Patricia; Pike, Malcolm C.; Modugno, Francesmary; Rossing, Mary Anne; Ness, Roberta B.; Pharoah, Paul D.P.; Stram, Daniel O.; Wu, Anna H.; Pearce, Celeste Leigh

    2016-01-01

    Objective Ovarian cancer is a hormone-related disease with a strong genetic basis. However, none of its high-penetrance susceptibility genes and GWAS-identified variants to date are known to be involved in hormonal pathways. Given the hypothesized etiologic role of gonadotropins, an assessment of how variability in genes involved in the gonadotropin signaling pathway impacts disease risk is warranted. Methods Genetic data from 41 ovarian cancer study sites were pooled and unconditional logistic regression was used to evaluate whether any of the 2185 SNPs from 11 gonadotropin signaling pathway genes was associated with ovarian cancer risk. A burden test using the admixture likelihood (AML) method was also used to evaluate gene-level associations. Results We did not find any genome-wide significant associations between individual SNPs and ovarian cancer risk. However, there was some suggestion of gene-level associations for four gonadotropin signaling pathway genes: INHBB (p = 0.045, mucinous), LHCGR (p = 0.046, high-grade serous), GNRH (p = 0.041, high-grade serous), and FSHB (p = 0.036, overall invasive). There was also suggestive evidence for INHA (p = 0.060, overall invasive). Conclusions Ovarian cancer studies have limited sample numbers, thus fewer genome-wide susceptibility alleles, with only modest associations, have been identified relative to breast and prostate cancers. We have evaluated the majority of ovarian cancer studies with biological samples, to our knowledge, leaving no opportunity for replication. Using both our understanding of biology and powerful gene-level tests, we have identified four putative ovarian cancer loci near INHBB, LHCGR, GNRH, and FSHB that warrant a second look if larger sample sizes and denser genotype chips become available. PMID:25528498

  13. How do patients at risk portray candidates for coronary heart disease? A qualitative interview study

    DEFF Research Database (Denmark)

    Frich, J.C.; Malterud, K.; Fugelli, P.

    2007-01-01

    OBJECTIVE: To explore how patients at risk of coronary heart disease (CHD) portray candidates for CHD. DESIGN: Qualitative interview study. SETTING: Norway. SUBJECTS: A total of 20 men and 20 women diagnosed with heterozygous familial hypercholesterolemia (FH) recruited through a lipid clinic. MAIN...... OUTCOME MEASURES: Participants' beliefs concerning persons who are considered candidates for CHD. RESULTS: Some participants believed that CHD could happen to anyone, while the majority conveyed detailed notions of persons they considered to be likely victims of CHD. Participants often portrayed...... the coronary candidate as someone who was different from themselves. Among those who mentioned gender, all presented the candidate as a man. Some women said that they had to reconcile themselves to being at risk of CHD, since they at first had conceived CHD as a man's disease. While some participants...

  14. Immersion studies on candidate container alloys for the Tuff Repository

    International Nuclear Information System (INIS)

    Beavers, J.A.; Durr, C.L.

    1991-05-01

    Cortest Columbus Technologies (CC Technologies) is investigating the long-term performance of container materials used for high-level radioactive waste packages. This information is being developed for the Nuclear Regulatory Commission to aid in their assessment of the Department of Energy's application to construct a geologic repository for disposal of high-level radioactive waste. This report summarizes the results of exposure studies performed on two copper-base and two Fe-Cr-Ni alloys in simulated Tuff Repository conditions. Testing was performed at 90 degrees C in three environments; simulated J-13 well water, and two environments that simulated the chemical effects resulting from boiling and irradiation of the groundwater. Creviced specimens and U-bends were exposed to liquid, to vapor above the condensed phase, and to alternate immersion. A rod specimen was used to monitor corrosion at the vapor-liquid interface. The specimens were evaluated by electrochemical, gravimetric, and metallographic techniques following approximately 2000 hours of exposure. Results of the exposure tests indicated that all four alloys exhibited acceptable general corrosion rates in simulated J-13 well water. These rates decreased with time. Incipient pitting was observed under deposits on Alloy 825 and pitting was observed on both Alloy CDA 102 and Alloy CDA 715 in the simulated J-13 well water. No SCC was observed in U-bend specimens of any of the alloys in simulated J-13 well water. 33 refs., 48 figs., 23 tabs

  15. Candidate gene study of HOXB1 in autism spectrum disorder

    Directory of Open Access Journals (Sweden)

    Muscarella Lucia A

    2010-05-01

    Full Text Available Abstract Background HOXB1 plays a major role in brainstem morphogenesis and could partly determine the cranial circumference in conjunction with HOXA1. In our sample, HOXA1 alleles significantly influence head growth rates both in autistic patients and in population controls. An initial report, suggesting that HOXB1 could confer autism vulnerability in interaction with HOXA1, was not confirmed by five small association studies. Methods Our sample includes 269 autistic individuals, belonging to 219 simplex and 28 multiplex families. A mutational analysis of the two exons and flanking intronic sequences of the HOXB1 gene was carried out in 84 autistic patients by denaturing high performance liquid chromatography, followed by DNA sequencing. Identified rare variants were then searched by a restriction analysis in 236 autistic patients and 325-345 controls. Case-control and family-based association studies were performed on two common variants in 169 Italian patients versus 184 Italian controls and in 247 trios. Results We identified three common polymorphisms, rs72338773 [c.82insACAGCGCCC (INS/nINS], rs12939811 [c.309A>T (Q103H], and rs7207109 [c.450G>A (A150A] and three rare variants, namely IVS1+63G>A, rs35115415 [c.702G>A (V234V] and c.872_873delinsAA (S291N. SNPs rs72338773 and rs12939811 were not associated with autism, using either a case-control (alleles, exact P = 0.13 or a family-based design [transmission/disequilibrium test (TDTχ2 = 1.774, P = 0.183]. The rare variants, all inherited from one of the parents, were present in two Italian and in two Caucasian-American families. Autistic probands in two families surprisingly inherited a distinct rare variant from each parent. The IVS1+63A allele was present in 3/690 control chromosomes, whereas rare alleles at rs35115415 and c.872_873delinsAA (S291N were not found in 662 and 650 control chromosomes, respectively. The INS-T309 allele influenced head size, but its effect appears more modest

  16. Use of the discourse analysis method to study current political practice (by the example of representation of the political leader image

    Directory of Open Access Journals (Sweden)

    Frolova Nadezhda

    2016-01-01

    Full Text Available The potentialities in the application of the discourse analysis method to study a political discourse as a current political practice are shown. The authors, using the Foucault methodology, offer a sociological definition for the political discourse. It is the authors’ opinion that the approach mentioned allows investigating a political discourse as a practice for the formation of a certain reality, specific agents, institutions and organizations. A political discourse is a simulative dynamic model of political area where various subdiscourses interact, thus creating their own ideas of policy, symbols and images. Subdiscourses of political leaders become dominating. Inasmuch as a political discourse in a current political system is carried out with the aid of mass media, it could be considered as a media discourse of policy. The authors consider the representation as a basic mechanism for the formation of a political discourse, by the example of the representation of the image of V.V. Putin, the President of the Russian Federation. The representation of a political leader image in a political discourse has a number of peculiarities. It is carried out on the basis of certain principles with the aid of the system of political codes. Empiric investigations allowed making a conclusion that the main symbolic image for the Russian President is an image of a super-hero. It is the authors’ opinion, the image of V.V. Putin as a leader super-hero is determined by the specificity of the Russian political culture within the limits of which a leader is a center of power establishing an authoritarian style of ruling. The authors show the process of the political legitimacy displacement from the institutional level to the personal one by means of mass media. A political leader gains a status of a subject establishing moral, social and value reference points for the whole of the society.

  17. Broadcast Political Advertisements and the Public Political Debate.

    Science.gov (United States)

    Martin, Howard H.

    The method of campaigning politically on television has changed markedly between 1952, when speeches by candidates were the prevalent mode of television campaigning, and 1972, when 60-second and 30-second spot announcements had almost replaced broadcast addresses. However, studies show that spots do not constitute an important source of political…

  18. Political innovations

    DEFF Research Database (Denmark)

    Sørensen, Eva

    2017-01-01

    are mainly interested in assessing and promoting innovations in public service delivery, but have paid little or no attention to the need for innovations in polity, politics and policy. This article develops a research agenda for studying innovations in political institutions, in the political process...... and in policy outputs. It proposes a number of research themes related to political innovations that call for scholarly attention, and identifies push and pull factors influencing the likelihood that these themes will be addressed in future research....

  19. Performing Femininity in Japanese Politics: Chikage Ogi Case Study

    Directory of Open Access Journals (Sweden)

    Alison Luke

    2016-07-01

    Full Text Available Women’s access to the political sphere in Japan has been limited by structural constraints which perpetuate their roles primarily as housewives and mothers. Some women who seek to become professional politicians use these images of traditional femininity as a deliberate tactic in political campaigns to provide a culturally acceptable way for them to express their political views. This paper analyses the life of Chikage Ōgi, a Japanese politician who was once a Takarazuka actress, in order to develop a deeper understanding of the ways in which gender-role expectations restrict women’s access to opportunities throughout their life course and the pragmatic ways that women strive to achieve their goals despite this. Ōgi used the performance skills she developed during her time as an actress to enhance her political image and fulfil her political ambitions. This paper highlights Ōgi’s creativity in enacting agency in Japan’s male-dominated political sphere and demonstrates the complex ways she both upheld and subverted gender norms in order to achieve political longevity.

  20. Examination of the Professional Self-Esteem of Teacher Candidates Studying at a Faculty of Education

    Science.gov (United States)

    Aral, Neriman; Gursoy, Figen; Ceylan, Remziye; Bicakci, Mudriye Yildiz

    2009-01-01

    This study aims to determine the professional self-esteem levels of teacher candidates studying at the Faculty of Education, Ahi Evran University, Kirsehir, Turkey, to examine whether certain variables create any differences in their professional self-esteem levels and to propose suggestions in accordance with the results. The study was conducted…

  1. Lobbying and political polarization

    OpenAIRE

    Ursprung, Heinrich W.

    2002-01-01

    Standard spatial models of political competition give rise to equilibria in which the competing political parties or candidates converge to a common position. In this paper I show how political polarization can be generated in models that focus on the nexus between pre-election interest group lobbying and electoral competition.

  2. POLITICAL SCIENCES AND THE SECURITY AND DEFENSE STUDIES. PRECISIONS AND PROJECTIONS

    Directory of Open Access Journals (Sweden)

    JUAN FUENTES VERA

    2018-02-01

    Full Text Available This article focus on political science as a matter of study in the programs of the National Academy for Political and Strategic Studies, in order to explain the reason of including this discipline, particularly in its relation with security and defense. It is focused on the object of study of political science, thus delivering precisions about the concept of politics among others related. It also emphasizes some aspects that have been important in this discipline, including some modern epistemological debates, and also open the scope of possibilities that today can be offered as matters of study in a world yielded to the dynamics of the globalization.

  3. Studi Tentang Political Tie, Pengaruhnya Terhadap Keputusan Pemberian Kredit Bank di Indonesia

    Directory of Open Access Journals (Sweden)

    Elisa Tjondro

    2012-01-01

    Full Text Available This study uses bank loan data to examine the effect of (political tie between the company and the government to on the assessment of companies financial leverage and profitability in the bank lending decisions in Indonesia. The numbers of samples are 1465 observations. This study uses moderated regression analysis (MRA. The study finds that a political tie affect corporate profitability assessment in bank lending decisions. Firms with lower profitability receive larger bank loan because their political tie (rent-seeking hypothesis. However, this study inds that a political tie does not affect the assessment of financial leverage in bank's lending decisions. This finding also supports Faccio (2010, Fisman (2001, and Backman (2001. Indonesia condition which has a weak institutional regulation and high information asymmetry is beneficial for companies that have a political tie. This leads to more trusted political tie as an indicator of the profitability.

  4. Preformulation study of the vaccine candidate TAB9 against HIV-1.

    Science.gov (United States)

    Expósito Raya, Néstor; García Díaz, Alina; Carrazana López, Yamilka; Quintana Vazquez, Diógenes; Pichardo Díaz, Dagmara; Martínez de la Puente, Nieves; Duarte Cano, Carlos

    2002-10-01

    A preformulation study was performed for the evaluation of a vaccine candidate against HIV-1. Aluminium hydroxide was used in the preformulation. However, this adjuvant is not a good adsorbent for basic proteins since it is positively charged at a physiological pH. In the present study, we determined the adsorption of TAB9 (basic protein, pI: 11.3) by treating Alhydrogel with different ions. The immunogenicity of the vaccine candidate against HIV was also evaluated using three batches, 9801-A, 9802-A and 9803-A, and a placebo P-001. The evaluation was performed twice (0 and 9 months). Each batch was tested using groups of 10 mice that had a single inoculation. The results showed that the protein was totally adsorbed to the aluminium gel. Seroconvertion was attained in all analysed batches, indicating the potentiality of TAB9 as a vaccine candidate.

  5. Performing political partnership - A study of EU-Liberia relations

    OpenAIRE

    Andersen, Sigrid Bjerre

    2011-01-01

    This thesis investigates the concept of political partnership as a way of describing relations between the European Union and the ACP countries (Africa, Carribean and Pacific). The concept reflects two trends in current development discourse. On the one hand, the renaming of donor-recipient relations as 'partnerships', implying a more equal status between donors and recipients. On the other hand, the bringing in of political principles into donor-recipient relations, based on the philosophy t...

  6. Party website – instrument of political communication. Case study: www.psd.ro

    Directory of Open Access Journals (Sweden)

    Monica Pătruţ

    2012-06-01

    Full Text Available Romanian political parties’ websites have developed especially after 2000 and have been used to disseminate information about candidates, campaigns and political agendas. Combining the quantitative content analysis with well-known models I will quantify the degree in which the Romanian Social Democratic Party website contributes to informing, connecting, involving, and mobilizing visitors. Another objective of the analysis is to pinpoint the place that websites occupy on the trajectory web 1.0 – web 2.0. The findings show that the political website is used more to inform and less to involve or mobilize visitors and that the SDP website is far from the web 2.0. taking account the virtual practices performed.

  7. Characteristics study of bentonite as candidate of buffer materials for radioactive waste disposal system

    International Nuclear Information System (INIS)

    Suryantoro; Arimuladi, S.P.; Sastrowardoyo, P.B.

    1998-01-01

    Literature studies on bentonite characteristic of, as candidate for radioactive waste disposal system, have been conducted. Several information have been obtained from references, which would be contributed on performance assessment of engineered barrier. The functions bentonite includes the buffering of chemical and physical behavior, i.e. swelling property, self sealing, hydraulic conductivities and gas permeability. This paper also presented long-term stability of bentonite in natural condition related to the illitisazation, which could change its buffering capacities. These information, showed that bentonite was satisfied to be used for candidate of buffer materials in radioactive waste disposal system. (author)

  8. West German nuclear politics: a study of international cooperative behavior

    International Nuclear Information System (INIS)

    Driscoll, R.F.

    1983-01-01

    This dissertation is an investigation of the motivations behind West German policies and behavior in the area of nuclear politics. It examines and attempts to explain this behavior using a taxonomy built around the factors of vulnerability, power, domestic support, and autonomy. These are called international cooperative behavior factors. Chapters I and II develop the taxonomy and define the factors in terms of the Federal Republic. Chapter III covers the period up through the functioning of the Nuclear Planning Group, while Chapter IV analyzes NATO's December 1979 modernization decision. The presentation is less chronological and more selective: it focuses on the four international cooperative behavior factors as explanatory concepts. Chapter V examines the utility of the taxonomy. It concludes that the factors of autonomy, domestic support and vulnerability appear to be key in understanding and predicting West German nuclear behavior. The chapter then studies the potential applicability of the taxonomy to other nations or issues. It concludes that the factors are very nation-specific, but they do in fact provide a useful classification and explanatory scheme

  9. Participant Action Research in Political, Psychological, and Gender Studies

    Directory of Open Access Journals (Sweden)

    Olga Lucia Obando-Salazar

    2006-09-01

    Full Text Available Qualitative methodology is used in social and intervention research because it facilitates a deeper analysis of causal factors and development of alternative solutions to social problems. Based on the findings of three studies in the field of political and gender psychology, this article focuses on Participant Action Research (PAR as a useful qualitative approach to deal with social phenomena, such as racism, violence against women, and the problem of children and youth who have been dislocated as the result of armed conflict and sheltered by the Colombian government's program for persons relocated to civil society. This article is composed of three parts. The first part offers historical and theoretical background to the Action Research (AR paradigm, its validation criteria and their meaning for the development of the Latin American rendering of Participant Action Research (PAR. The second part synthesizes trends in the AR approach in the United States and Germany, discusses feminist research and compares these to trends in PAR in Latin America. The third part is a description of Participant Action Research as an intervention method, including features, models, goals, and concepts. URN: urn:nbn:de:0114-fqs060438

  10. An Exploration of Virtual Study Groups Used to Prepare Candidates for a Professional Certification Exam

    Science.gov (United States)

    Kayne Chaplock, Sharon

    2011-01-01

    Professional credentials earned through certification programs are becoming an important way to demonstrate competency within a given discipline. With the globalization of business enterprises and associations, these credentials are eagerly sought by people located throughout the world. Candidates for these credentials often study together using…

  11. A Study towards Views of Teacher Candidates about National and Global Environmental Problems

    Science.gov (United States)

    Alagoz, Bulent; Akman, Ozkan

    2016-01-01

    In this research, determination of primary school, social studies and mathematics candidate teachers' awareness and susceptibility levels about environmental problems, solution suggestions about these problems, activities used in environmental education and views about environmental education were targeted. Sample of this research comprised of 449…

  12. TPACK Survey Development Study for Social Sciences Teachers and Teacher Candidates

    Science.gov (United States)

    Akman, Özkan; Güven, Cemal

    2015-01-01

    The purpose of this research is to develop a scale for analyzing the technological pedagogical and content knowledge (TPACK) and self-efficacy perceptions of the social sciences teachers and teacher candidates. During the development process, an item pool has been generated by evaluating the studies made in the literature. Also, after opinions…

  13. Disrupting ELL Teacher Candidates' Identities: Indigenizing Teacher Education in One Study Abroad Program

    Science.gov (United States)

    Kasun, G. Sue; Saavedra, Cinthya M.

    2016-01-01

    In this article, the researchers describe and theorize the challenges and promises of exposing preservice teachers' identities to indigenous, critical second language teaching experiences in one study abroad program in Mexico. The eight teacher candidates who participated in this 4-week program were predominantly white, like the majority of…

  14. The Preparation of Teacher Candidates for K-12 Online Learning Environments: A Case Study

    Science.gov (United States)

    Williams, Nicole V.

    2015-01-01

    The purpose of this study was to determine how teacher education programs may better prepare teacher candidates to teach in K-12 online learning environments. The primary research question addressed was: What specific knowledge, skills, and dispositions should teacher education programs include in their curriculum to better prepare teacher…

  15. How Internal Political Efficacy Translates Political Knowledge Into Political Participation

    Directory of Open Access Journals (Sweden)

    Frank Reichert

    2016-05-01

    Full Text Available This study presents evidence for the mediation effect of political knowledge through political self-efficacy (i.e. internal political efficacy in the prediction of political participation. It employs an action theoretic approach—by and large grounded on the Theory of Planned Behaviour—and uses data from the German Longitudinal Election Study to examine whether political knowledge has distinct direct effects on voting, conventional, and/or unconventional political participation. It argues that political knowledge raises internal political efficacy and thereby indirectly increases the chance that a citizen will participate in politics. The results of mediated multiple regression analyses yield evidence that political knowledge indeed translates into internal political efficacy, thus it affects political participation of various kinds indirectly. However, internal political efficacy and intentions to participate politically yield simultaneous direct effects only on conventional political participation. Sequentially mediated effects appear for voting and conventional political participation, with political knowledge being mediated by internal political efficacy and subsequently also by behavioural intentions. The mediation patterns for unconventional political participation are less clear though. The discussion accounts for restrictions of this study and points to questions for answer by future research.

  16. How Internal Political Efficacy Translates Political Knowledge Into Political Participation

    Science.gov (United States)

    Reichert, Frank

    2016-01-01

    This study presents evidence for the mediation effect of political knowledge through political self-efficacy (i.e. internal political efficacy) in the prediction of political participation. It employs an action theoretic approach—by and large grounded on the Theory of Planned Behaviour—and uses data from the German Longitudinal Election Study to examine whether political knowledge has distinct direct effects on voting, conventional, and/or unconventional political participation. It argues that political knowledge raises internal political efficacy and thereby indirectly increases the chance that a citizen will participate in politics. The results of mediated multiple regression analyses yield evidence that political knowledge indeed translates into internal political efficacy, thus it affects political participation of various kinds indirectly. However, internal political efficacy and intentions to participate politically yield simultaneous direct effects only on conventional political participation. Sequentially mediated effects appear for voting and conventional political participation, with political knowledge being mediated by internal political efficacy and subsequently also by behavioural intentions. The mediation patterns for unconventional political participation are less clear though. The discussion accounts for restrictions of this study and points to questions for answer by future research. PMID:27298633

  17. Political Cartoons in the EFL and American Studies Classroom

    Directory of Open Access Journals (Sweden)

    Christianna Stavroudis

    2014-10-01

    Full Text Available Political cartoons are anything but innocent caricatures. They have been described as “a confrontational art form” (Oliphant 25, as “purposefully designed to elicit strong emotions and reactions from readers” (Long, Bunch, and Lloyd 651, and as “among the more extreme forms of expression” (Long, Bunch, and Lloyd 651. Stories abound with the harsh punishments endured by political cartoonists under oppressive regimes. One might even say that what allows liberal and conservative American cartoonists to feel any sense of solidarity with one another is their bond through the First Amendment and their belief in the democratic enterprise that is criticizing government.

  18. AUGUSTINIAN MODEL IN THE BYZANTINE POLITICAL THINKING. CASE STUDY: THE ELEMENTS OF POLITICAL AUGUSTINISM IN THE CURRENT ROMANIAN MENTALITY

    Directory of Open Access Journals (Sweden)

    ANDREI TINU

    2012-05-01

    Full Text Available The byzantine society, de jure and de facto heir of the Greco-Roman world, has it’s own philosophy, it’s own structure model and policy thinking. Without doubt, for the New Rome this model is that sprang from the Christian teachings, and as a philosophy it harmoniously blends the legacy of the Roman world with Blessed Augustine’s thinking about man and city which itself is a symbiosis between the acquired pagan knowledge and Christian experience of the latter. The Byzantine fortress (The Empire-n.n. will use religion as the main instrument for political and social consolidation. Religion (Christianity – n.n. is, for the Byzantine monarchy , the path to divinity, immortality... The Byzantine Christianity is not just a "phrase invented by them" as in the words of Eminescu, but a complex mechanism which represents the totality of good concepts about the world and about life of the constantinopolitan city.In preparing this study we started from the model offered by St. Augustine, "De Civitate Dei", a model which compares the two types of cities - people's city, with all its flaws, and the City of God, personified by the Church to which the Christian Roman Empire provides the Regnum. Our study tries to reflect how the model of the two cities becomes a political ideology of the Byzantine Empire and, arch over time, how it is manifested in the public and political mind of the Romanian society. This research tries to increase the understanding of the mental archetypes amongst those who are active participants in public life in Romania. However, we want our message to be disseminated in a wider public and to provide the possibility of assimilation, as much as it can, of the participatory political culture. Thus, the study becomes an attempt of reporting the Byzantine society, respectively the current Romanian society, to the model of the three types of political culture offered by Almond and Verba - participatory, parochial and dependent.

  19. Infrared study of new star cluster candidates associated to dusty globules

    Science.gov (United States)

    Soto King, P.; Barbá, R.; Roman-Lopes, A.; Jaque, M.; Firpo, V.; Nilo, J. L.; Soto, M.; Minniti, D.

    2014-10-01

    We present results from a study of a sample of small star clusters associated to dusty globules and bright-rimmed clouds that have been observed under ESO/Chile public infrared survey Vista Variables in the Vía Láctea (VVV). In this short communication, we analyse the near-infrared properties of a set of four small clusters candidates associated to dark clouds. This sample of clusters associated to dusty globules are selected from the new VVV stellar cluster candidates developed by members of La Serena VVV Group (Barbá et al. 2014). Firstly, we are producing color-color and color-magnitude diagrams for both, cluster candidates and surrounding areas for comparison through PSF photometry. The cluster positions are determined from the morphology on the images and also from the comparison of the observed luminosity function for the cluster candidates and the surrounding star fields. Now, we are working in the procedures to establish the full sample of clusters to be analyzed and methods for subtraction of the star field contamination. These clusters associated to dusty globules are simple laboratories to study the star formation relatively free of the influence of large star-forming regions and populous clusters, and they will be compared with those clusters associated to bright-rimmed globules, which are influenced by the energetic action of nearby O and B massive stars.

  20. Multiplicity and properties of Kepler planet candidates: High spatial imaging and RV studies*

    Directory of Open Access Journals (Sweden)

    Aceituno J.

    2013-04-01

    Full Text Available The Kepler space telescope is discovering thousands of new planet candidates. However, a follow up program is needed in order to reject false candidates and to fully characterize the bona-fide exoplanets. Our main aims are: 1./ Detect and analyze close companions inside the typical Kepler PSF to study if they are the responsible of the dim in the Kepler light curves, 2./ Study the change in the stellar and planetary parameters due to the presence of an unresolved object, 3./ Help to validate those Kepler Objects of Interest that do not present any object inside the Kepler PSF and 4./ Study the multiplicity rate in planet host candidates. Such a large sample of observed planet host candidates allows us to do statistics about the presence of close (visual or bounded companions to the harboring star. We present here Lucky Imaging observations for a total amount of 98 Kepler Objects of Interest. This technique is based on the acquisition of thousands of very short exposure time images. Then, a selection and combination of a small amount of the best quality frames provides a high resolution image with objects having a 0.1 arcsec PSF. We applied this technique to carry out observations in the Sloan i and Sloan z filters of our Kepler candidates. We find blended objects inside the Kepler PSF for a significant percentage of KOIs. On one hand, only 58.2% of the hosts do not present any object within 6 arcsec. On the other hand, we have found 19 companions closer than 3 arcsec in 17 KOIs. According to their magnitudes and i − z color, 8 of them could be physically bounded to the host star. We are also collecting high-spectral resolution spectroscopuy in order to derive the planet properties.

  1. Zero-gravity cloud physics laboratory: Candidate experiments definition and preliminary concept studies

    Science.gov (United States)

    Eaton, L. R.; Greco, R. V.; Hollinden, A. B.

    1973-01-01

    The candidate definition studies on the zero-g cloud physics laboratory are covered. This laboratory will be an independent self-contained shuttle sortie payload. Several critical technology areas have been identified and studied to assure proper consideration in terms of engineering requirements for the final design. Areas include chambers, gas and particle generators, environmental controls, motion controls, change controls, observational techniques, and composition controls. This unique laboratory will allow studies to be performed without mechanical, aerodynamics, electrical, or other type techniques to support the object under study. This report also covers the candidate experiment definitions, chambers and experiment classes, laboratory concepts and plans, special supporting studies, early flight opportunities and payload planning data for overall shuttle payload requirements assessments.

  2. Learning Political Science with Prediction Markets: An Experimental Study

    Science.gov (United States)

    Ellis, Cali Mortenson; Sami, Rahul

    2012-01-01

    Prediction markets are designed to aggregate the information of many individuals to forecast future events. These markets provide participants with an incentive to seek information and a forum for interaction, making markets a promising tool to motivate student learning. We carried out a quasi-experiment in an introductory political science class…

  3. The Politics of Multilingual Communication: Case Studies and Research Agendas

    NARCIS (Netherlands)

    Marácz, L.; Craze, S.; Lempp, F.

    2014-01-01

    Due to globalisation, and different forms of migration and mobility there is a proliferation of linguistic diversity and multilingual communication. At the same time the recognition of the use of one’s first language receives more and more support in international political, legal and institutional

  4. Politeness in Language Use: A Study of Undergraduates of Nnamdi ...

    African Journals Online (AJOL)

    Politeness in language is a very important aspect of communication. This can be referred to as 'tact'. Normally conversation works best if both parties are cooperative. This involves among other things avoiding speaking or behaving in a thoughtless and inconsiderate manner .We each have expectations as to how we ...

  5. VERBAL HYGIENE AND ETHNIC POLITICS IN NIGERIA: A STUDY ...

    African Journals Online (AJOL)

    Dean SPGS NAU

    Social context as a political, psychological, religious, cultural, and educational background of an individual ... selected media textual data to discover the extent to which verbal hygiene obtains in one of the most ... hygiene can be examined during and after every communication process. Another central idea to verbal ...

  6. The relevance of political prestudies for implementation studies of cognitive services in community pharmacies

    DEFF Research Database (Denmark)

    Kaae, Susanne; Traulsen, Janine Marie; Søndergaard, Birthe

    2009-01-01

    serves as an example of this approach and is described in detail. Documentary analysis was used in order to gain knowledge of the political background of the ITAS. RESULTS: Political pre-studies provide a more precise understanding of the background of the cognitive services and the way they are being...

  7. Teaching the Indian Emergency as a Case Study in Introductory Comparative Politics.

    Science.gov (United States)

    Wittman, Philip

    One method of dramatizing the constant state of crisis management in developing countries is to have students in introductory college comparative political science classes study India's political system, which is under stress because of regional, linguistic, and cultural pluralism. This paper, a result of the 1987 Fulbright Summer Seminar to…

  8. Oil Politics and its social implications in the Niger Delta: A study of ...

    African Journals Online (AJOL)

    Oil Politics and its social implications in the Niger Delta: A study of Obari Gomba's Pearls of the Mangrove. Tambari Ogbonanwii Dick. Abstract. The oil politics in the Niger Delta has assumed a global dimension. It is stronger and more complex by the day. It is now a diplomatic weapon even more deadly and efficient than ...

  9. Audience Responses and the Context of Political Speeches

    OpenAIRE

    Choi, Hyangmi; Bull, Peter; Reed, Darren James

    2016-01-01

    Previous studies showed that cultural dimensions (individualism and collectivism) are related to audience behavior in responding to political speeches. However, this study suggests that speech context is an important issue to be considered in understanding speaker-audience interaction in political speeches. Forms of response, audience behavior, and response rates were analyzed in three speech contexts: acceptance speeches to nomination as political parties’ candidates for presidential electio...

  10. A candidate gene association study of bone mineral density in an Iranian population.

    Directory of Open Access Journals (Sweden)

    Seyed Alireza Dastgheib

    2016-10-01

    Full Text Available The genetic epidemiology of variation in bone mineral density (BMD and osteoporosis is not well studied in Iranian populations and needs more research. We report a candidate gene association study of BMD variation in a healthy cross sectional study of 501 males and females sampled from the IMOS study Shiraz, Iran. We selected to study the association with 21 SNPs located in the 7 candidate genes LRP5, RANK, RANKL, OPG, P2RX7, VDR and ESR1. BMD was measured at the three sites L2-L4, neck of femur and total hip. Association between BMD and each SNP was assessed using multiple linear regression assuming an allele dose (additive effect on BMD (adjusted for age and sex. Statistically significant (at the unadjusted 5% level associations were seen with 7 SNPs in 5 of the candidate genes. Two SNPs showed statistically significant association with more than one BMD site. Significant association was seen between BMD at all three sites with the VDR SNP rs731246 (L2-L4 p=0.038; neck of femur p=0.001 and total hip p<0.001. The T allele was consistently associated with lower BMD than the C allele. Significant association was also seen for the P2RX7 SNP rs3751143 where the G allele was consistently associated with lower BMD than the T allele, (L2-L4 p=0.069; neck of femur p=0.024, total hip p=0.045.

  11. SELF-ESTEEM AND PERSONALITY TYPE IN POLITICALLY ENGAGED PEOPLE: A PILOT STUDY

    Directory of Open Access Journals (Sweden)

    Irina MACSINGA

    2011-06-01

    Full Text Available The Romanian political institution is destined to survive in the face of the individual‘s ideological abandonment, passivity and reserve, as well as in the face of a society denouncing the mediocrity of the political class. Based on these considerations, this pilot study sets out to explore and reveal specific personality traits of the Romanian politicians, including the level of selfesteem. A total of 80 participants (divided into two groups, with or without political engagement completed the Myers-Briggs Type Indicator (MBTI and the Rosenberg‘s Self-Esteem Scale (RSES. The results have shown that politically engaged people have a predominant Extrovert Intuitive Feeling Judicative personality type; however, regarding self-esteem, no significant differences were identified in comparison to the group of persons having no political engagement. The results of this pilot study are of interest allowing a better understanding of a politician‘s mindset and behavior

  12. Molecular genetic gene-environment studies using candidate genes in schizophrenia: a systematic review.

    Science.gov (United States)

    Modinos, Gemma; Iyegbe, Conrad; Prata, Diana; Rivera, Margarita; Kempton, Matthew J; Valmaggia, Lucia R; Sham, Pak C; van Os, Jim; McGuire, Philip

    2013-11-01

    The relatively high heritability of schizophrenia suggests that genetic factors play an important role in the etiology of the disorder. On the other hand, a number of environmental factors significantly influence its incidence. As few direct genetic effects have been demonstrated, and there is considerable inter-individual heterogeneity in the response to the known environmental factors, interactions between genetic and environmental factors may be important in determining whether an individual develops the disorder. To date, a considerable number of studies of gene-environment interactions (G×E) in schizophrenia have employed a hypothesis-based molecular genetic approach using candidate genes, which have led to a range of different findings. This systematic review aims to summarize the results from molecular genetic candidate studies and to review challenges and opportunities of this approach in psychosis research. Finally, we discuss the potential of future prospects, such as new studies that combine hypothesis-based molecular genetic candidate approaches with agnostic genome-wide association studies in determining schizophrenia risk. © 2013 Elsevier B.V. All rights reserved.

  13. Major depressive disorder: insight into candidate cerebrospinal fluid protein biomarkers from proteomics studies.

    Science.gov (United States)

    Al Shweiki, Mhd Rami; Oeckl, Patrick; Steinacker, Petra; Hengerer, Bastian; Schönfeldt-Lecuona, Carlos; Otto, Markus

    2017-06-01

    Major Depressive Disorder (MDD) is the leading cause of global disability, and an increasing body of literature suggests different cerebrospinal fluid (CSF) proteins as biomarkers of MDD. The aim of this review is to summarize the suggested CSF biomarkers and to analyze the MDD proteomics studies of CSF and brain tissues for promising biomarker candidates. Areas covered: The review includes the human studies found by a PubMed search using the following terms: 'depression cerebrospinal fluid biomarker', 'major depression biomarker CSF', 'depression CSF biomarker', 'proteomics depression', 'proteomics biomarkers in depression', 'proteomics CSF biomarker in depression', and 'major depressive disorder CSF'. The literature analysis highlights promising biomarker candidates and demonstrates conflicting results on others. It reveals 42 differentially regulated proteins in MDD that were identified in more than one proteomics study. It discusses the diagnostic potential of the biomarker candidates and their association with the suggested pathologies. Expert commentary: One ultimate goal of finding biomarkers for MDD is to improve the diagnostic accuracy to achieve better treatment outcomes; due to the heterogeneous nature of MDD, using bio-signatures could be a good strategy to differentiate MDD from other neuropsychiatric disorders. Notably, further validation studies of the suggested biomarkers are still needed.

  14. Expectation Violation in Political Decision Making: A Psychological Case Study

    Directory of Open Access Journals (Sweden)

    Michael Öllinger

    2017-10-01

    Full Text Available Since the early Gestaltists there has been a strong interest in the question of how problem solvers get stuck in a mental impasse. A key idea is that the repeated activation of a successful strategy from the past results in a mental set (‘Einstellung’ which determines and constrains the option space to solve a problem. We propose that this phenomenon, which mostly was tested by fairly restricted experiments in the lab, could also be applied to more complex problem constellations and naturalistic decision making. We aim at scrutinizing and reconstructing how a mental set determines the misinterpretation of facts in the field of political decision making and leads in consequence to wrong expectations and an ill-defined problem representation. We will exemplify this psychological mechanism considering a historical example, namely the unexpected stabilization of the Franco regime at the end of World War II and its survival thereafter. A specific focus will be drawn to the significant observation that erroneous expectations were taken as the basis for decisions. This is congruent with the notion that in case of discrepancy between preconceived notions and new information, the former prevails over the new findings. Based on these findings, we suggest a theoretical model for expectation violation in political decision making and develop novel approaches for cognitive empirical research on the mechanisms of expectation violation and its maintenance in political decision making processes.

  15. Good governance and political culture: A case study of Bangladesh

    Directory of Open Access Journals (Sweden)

    Syed Serajul Islam

    2016-12-01

    Full Text Available In a democratic system it is essential to have a competitive, and a tolerant party system, but Bangladesh has experienced an intolerant and a confrontational party system that has created a deadlock and brought uncertainty to the whole country. Since 1990, except 2014, Bangladesh has witnessed four systematic peaceful free elections, one each--in 1991, 1996, 2001, and 2008. On January 5, 2014, however, a controversial election took place in which major opposition political parties did not participate except the ruling alliance parties. The two dominant parties—the Bangladesh Nationalist Party (BNP and the Awami League (AL—each won two previous free and fair elections, with the BNP winning in1991, and a BNP-led 4-party coalition in 2001, and the AL in 1996, and an AL-led 14 party alliance in 2008. However, from 2014 Bangladesh is heading towards an authoritarian system. All these are happening due to the lack of good governance. This article intends to emphasize that the political culture emanating from the party politics is retarding good governance in Bangladesh. This article argues that the cultural traits developed in the last four decades in various dimensions,, particularly in more recent years, have worked as an “earth-worm” in the fabrics of democracy in Bangladesh preventing ‘good governance’.

  16. Future possibilities for precise studies of the X(125) Higgs candidate

    CERN Multimedia

    CERN. Geneva; Zimmermann, Frank

    2012-01-01

    We present a summary of the state-of-the-art comparison relevant to possible studies of the X(125) Higgs boson candidate. The machines considered are the LHC and its upgrades, Linear and circular e+e- colliders such as ILC/CLIC or LEP3/TLEP, gamma-gamma colliders and muon colliders. The conclusions of the recent ICFA beam dynamics HF2012 workshop in Fermilab will also be shown.

  17. Candidate gene association studies in syndromic and non-syndromic cleft lip and palate

    Energy Technology Data Exchange (ETDEWEB)

    Daack-Hirsch, S.; Basart, A.; Frischmeyer, P. [Univ. of Iowa, IA (United States)] [and others

    1994-09-01

    Using ongoing case ascertainment through a birth defects registry, we have collected 219 nuclear families with non-syndromic cleft lip and/or palate and 111 families with a collection of syndromic forms. Syndromic cases include 24 with recognized forms and 72 with unrecognized syndromes. Candidate gene studies as well as genome-wide searches for evidence of microdeletions and isodisomy are currently being carried out. Candidate gene association studies, to date, have made use of PCR-based polymorphisms for TGFA, MSX1, CLPG13 (a CA repeat associated with a human homologue of a locus that results in craniofacial dysmorphogenesis in the mouse) and an STRP found in a Van der Woude syndrome microdeletion. Control tetranucleotide repeats, which insure that population-based differences are not responsible for any observed associations, are also tested. Studies of the syndromic cases have included the same list of candidate genes searching for evidence of microdeletions and a genome-wide search using tri- and tetranucleotide polymorphic markers to search for isodisomy or structural rearrangements. Significant associations have previously been identified for TGFA, and, in this report, identified for MSX1 and nonsyndromic cleft palate only (p = 0.04, uncorrected). Preliminary results of the genome-wide scan for isodisomy has returned no true positives and there has been no evidence for microdeletion cases.

  18. A multi-source, multi-study investigation of job performance prediction by political skill

    DEFF Research Database (Denmark)

    Blickle, G.; Ferris, G.R.; Munyon, T.P.

    2011-01-01

    Political skill is a social effectiveness construct with a demonstrated capacity to predict job performance. However, because performance prediction research in this area to date has made exclusive use of self-reports of political skill, and due to frequent distrust of self-ratings of constructs......-sectional and longitudinal designs, this research tested the hypotheses that employee political skill, measured from the perspective of employees' assessor A, will positively predict job performance rated by assessor B (i.e. Hypothesis 1a), and vice versa, that employee political skill measured by assessor B will predict...... in important personnel decisions, there is a need to investigate how multiple alternative sources of political skill and job performance measures relate, thus raising both theoretical and methodological issues. In three studies, employing a triadic data collection methodology, and utilising both cross...

  19. Organizational Life and Political Incorporation of Two Asian Immigrant Groups: A Case Study.

    Science.gov (United States)

    Aptekar, Sofya

    2009-10-14

    Civil society is the foundation of a healthy democracy but its immigrant element has received little attention. This paper is a case study of immigrant organizations of highly-skilled Asian Indians and Chinese immigrants in a suburban town of Edison, New Jersey. I find that civic participation of Asian Indian immigrants spills over into political incorporation while Chinese immigrant organizations remain marginalized. I argue the local processes of racialization are central in explaining differences in political incorporation of immigrants. In the local context, the Chinese are seen as successful but conformist model minorities and Asian Indians as invaders and troublemakers. The racialization of Asian Indians has resulted in more political activity and higher levels of political visibility of their organizations. The results highlight shortcomings of current assimilation theories, which give little space to civic and political incorporation and view human capital in an unqualifiedly positive light.

  20. Thermal stability study for candidate stainless steels of GEN IV reactors

    Energy Technology Data Exchange (ETDEWEB)

    Simeg Veternikova, J., E-mail: jana.veternikova@stuba.sk [Institute of Nuclear and Physical Engineering, Faculty of Electrical and Information Technology, Slovak University of Technology, Ilkovicova 3, 812 19 Bratislava (Slovakia); Degmova, J. [Institute of Nuclear and Physical Engineering, Faculty of Electrical and Information Technology, Slovak University of Technology, Ilkovicova 3, 812 19 Bratislava (Slovakia); Pekarcikova, M. [Institute of Materials Science, Faculty of Materials Science and Technology, Slovak University of Technology, Paulinska 16, 917 24 Trnava (Slovakia); Simko, F. [Department of Molten Salts, Institute of Inorganic Chemistry, Slovak Academy of Sciences, Dubravska cesta 9, 845 36 Bratislava (Slovakia); Petriska, M. [Institute of Nuclear and Physical Engineering, Faculty of Electrical and Information Technology, Slovak University of Technology, Ilkovicova 3, 812 19 Bratislava (Slovakia); Skarba, M. [Slovak University of Technology, Vazovova 5, 812 43 Bratislava (Slovakia); Mikula, P. [Institute of Nuclear and Physical Engineering, Faculty of Electrical and Information Technology, Slovak University of Technology, Ilkovicova 3, 812 19 Bratislava (Slovakia); Pupala, M. [Department of Molten Salts, Institute of Inorganic Chemistry, Slovak Academy of Sciences, Dubravska cesta 9, 845 36 Bratislava (Slovakia)

    2016-11-30

    Highlights: • Thermal resistance of advanced stainless steels were observed at 1000 °C. • GEN IV candidate steels were confronted to classic AISI steels. • ODS AISI 316 has weaker thermal resistance than classic AISI steel. • Ferritic ODS steels and NF 709 has better thermal resistance than AISI steels. - Abstract: Candidate stainless steels for GEN IV reactors were investigated in term of thermal and corrosion stability at high temperatures. New austenitic steel (NF 709), austenitic ODS steel (ODS 316) and two ferritic ODS steels (MA 956 and MA 957) were exposed to around 1000 °C in inert argon atmosphere at pressure of ∼8 MPa. The steels were further studied in a light of vacancy defects presence by positron annihilation spectroscopy and their thermal resistance was confronted to classic AISI steels. The thermal strain supported a creation of oxide layers observed by scanning electron microscopy (SEM).

  1. Boomers versus Millennials: Online Media Influence on Media Performance and Candidate Evaluations

    Directory of Open Access Journals (Sweden)

    Terri Towner

    2016-09-01

    Full Text Available Facebook posts, YouTube videos, tweets and wooing political bloggers have become standard practice in marketing political campaigns. Research has demonstrated the effect of new media on a host of politically-related behavior, including political participation, knowledge acquisition, group formation and self-efficacy. Yet, issues related to media trust, media performance and candidate evaluations have not been fully explored. In addition, much of the political marketing research looks exclusively at the Millennial age cohort, ignoring other age groups, particularly Baby Boomers. This case study addresses whether attention to traditional (i.e., television, hard-copy newspapers and radio and online media sources (i.e., political candidate websites, television network websites, online newspapers, Facebook, Twitter, YouTube, Tumblr and political blogs about the 2012 U.S. presidential campaign influences Millennials and Baby Boomers’ media trust and performance ratings, as well as candidate evaluations. Panel surveys were completed by both age cohorts, Millennials (n = 431 and Baby Boomers (n = 360, during the last two weeks of the presidential election. Findings indicate that traditional sources, specifically television, rather than online sources are significantly linked to media trust and performance ratings among both Boomers and Millennials. Attention to traditional media for campaign information predicts Boomers’ candidate evaluations, whereas Millennials’ candidate evaluations are influenced by online sources, such as Facebook and candidate websites.

  2. Education based thinking and behaving? Towards an identity perspective for studying education differentials in public opinion and political participation

    NARCIS (Netherlands)

    Spruyt, Bram; Kuppens, Toon

    2015-01-01

    Education based thinking and behaving? Towards and identity perspective for studying education differentials in public opinion and political participation Abstract Ever since scholars started studying public opinion and political behaviour, they have reported substantial educational differences.

  3. Photoeducation and photoprotection among liver transplant candidates: a cross-sectional study.

    Science.gov (United States)

    Mendes, Karina Dal Sasso; Rossin, Fabiana Murad; Ziviani, Luciana da Costa; Ribeiro, Kátia Prado; Zago, Márcia Maria Fontão; Ohler, Linda; de Castro-e-Silva, Orlando; Galvão, Cristina Maria

    2013-01-01

    The incidence of skin cancer after liver transplant ranges from 3% to 16%, considerably higher than that observed in the general population. Skin cancer causes 25% of deaths in patients who have survived more than 3 years after liver transplant. The objective of this study was to identify differences regarding the level of sun exposure, knowledge of potential risk factors, and photoprotection measures among liver transplant candidates and recipients. We carried out a prospective cross-sectional study with 100 patients enrolled at a liver transplant program in a Brazilian center. The patients were interviewed and received oral information regarding skin care and sun exposure. Results reveal that measures of photoprotection and photoeducation are more prevalent among recipients than among candidates. High degrees of solar exposure were observed more frequently among candidates, although recipients showed better knowledge about the risks of sun exposure. Educational actions concerning skin cancer prevention should be part of the guidelines given by the multidisciplinary team to the liver transplant patients, in particular, by the nursing team.

  4. Learning through Political Participation: A Case Study of Spanish Elders Involved in Political Organizations

    Science.gov (United States)

    Serrat, Rodrigo; Petriwskyj, Andrea; Villar, Feliciano; Warburton, Jeni

    2016-01-01

    Older people's civic participation contributes to community development while at the same time providing opportunities for personal growth in later life. One important dimension of civic participation that has been largely underexplored is informal learning. The aim of this study is to explore the learnings experienced by Spanish older people…

  5. The justification of studies in genetic epidemiology - political scaling in China Medical City.

    Science.gov (United States)

    Sleeboom-Faulkner, Margaret

    2018-04-01

    Genetic epidemiology examines the role of genetic factors in determining health and disease in families and in populations to help addressing health problems in a responsible manner. This paper uses a case study of genetic epidemiology in Taizhou, China, to explore ways in which anthropology can contribute to the validation of studies in genetic epidemiology. It does so, first, by identifying potential overgeneralizations of data, often due to mismatching scale and, second, by examining it's embedding in political, historical and local contexts. The example of the longitudinal cohort study in Taizhou illustrates dimensions of such 'political scaling'. Political scaling is a notion used here to refer to the effects of scaling biases in relation to the justification of research in terms of relevance, reach and research ethics. The justification of a project on genetic epidemiology involves presenting a maximum of benefits and a minimum of burden for the population. To facilitate the delineation of political scaling, an analytical distinction between donating and benefiting communities was made using the notions of 'scaling of relevance', 'scaling of reach' and 'scaling of ethics'. Political scaling results at least partly from factors external to research. By situating political scaling in the context of historical, political and local discourses, anthropologists can play a complementary role in genetic epidemiology.

  6. Comparative Area Studies and Middle East Politics after the Arab Uprisings

    Directory of Open Access Journals (Sweden)

    André Bank

    2015-05-01

    Full Text Available The Arab uprisings have brought about a new wave of Middle East political science research that seeks to comparatively account for the different political trajectories in the region. In order to situate these diverse post-2011 scholarly studies, this paper introduces Comparative Area Studies (CAS as an analytical perspective which combines the context sensitivity of area studies with the explicit and systematic use of comparisons. It finds that while intra-regional comparisons are the mainstay of political science studies of the Arab uprisings, there is also an emerging, very promising strand of cross-regional comparisons that draws on insights from, for example, the post-Soviet space or from European history. The paper concludes by evaluating the promises, risks and prospects of following a CAS perspective in the study of Middle East politics.

  7. Public political thought: bridging the sociological-philosophical divide in the study of legitimacy.

    Science.gov (United States)

    Abulof, Uriel

    2016-06-01

    The study of political legitimacy is divided between prescriptive and descriptive approaches. Political philosophy regards legitimacy as principled justification, sociology regards legitimacy as public support. However, all people can, and occasionally do engage in morally reasoning their political life. This paper thus submits that in studying socio-political legitimation - the legitimacy-making process - the philosophical ought and the sociological is can be bridged. I call this construct 'public political thought' (PPT), signifying the public's principled moral reasoning of politics, which need not be democratic or liberal. The paper lays PPT's foundations and identifies its 'builders' and 'building blocks'. I propose that the edifice of PPT is built by moral agents constructing and construing socio-moral order (nomization). PPT's building blocks are justificatory common beliefs (doxa) and the deliberative language of legitimation. I illustrate the merits of this groundwork through two empirical puzzles: the end of apartheid and the emergence of Québécois identity. © London School of Economics and Political Science 2016.

  8. Destructiveness in Political Discourse

    Directory of Open Access Journals (Sweden)

    Яна Александровна Волкова

    2016-12-01

    Full Text Available Destructiveness is among the fundamental discourse categories that play a significant role in the organization of communicative interaction and define the pragmatics of discourse; its study helps to understand some mechanisms and principles of communication, identify strategies and tactics used by a destructive communicative personality. The relevance of this study is determined by the increasing aggressiveness in various types of discourse, and, accordingly, by the need to extend the knowledge of destructive behavior of a communicative personality. The study is based on the theory of discourse-analysis and theory of destructiveness (Z. Harris, T. van Dijk, A. Buss, E. Fromm, D. Ponton, K. Hacker, R. Wodak. N. Arutyunova, V. Karasik, M. Makarov, E. Sheigal et al. Developing the theory of destructiveness and relying on Erich Fromm’s research (1973, we specify the concept of “destructiveness” in relation to the political discourse and compare it with the related concept of aggressiveness. The paper analyses the category of destructiveness in modern US political discourse, using excerpts from the speeches of the candidates for presidency of 2016. Particular attention is paid to the dominant destructive intention - to harm the reputation of the opponent and reduce his political chances, as well as to the functions of verbal aggression: on the one hand - to discredit the opponent, bring accusations, on the other hand - to poison the audience mind against him/her and arouse the feeling of danger posed by a political opponent. The analysis of verbal and nonverbal means of destructiveness in the US political discourse is carried out. The article concludes that abusive remarks of politicians do not result from spontaneous emotional outburst, but from an elaborated destructive strategy where the agonistic nature of political discourse stipulates the use of instrumental aggression (Buss, 1971 for the sake of the conquest of power, lowering the

  9. Do Personality and Organizational Politics Predict Workplace Victimization? A Study among Ghanaian Employees

    Directory of Open Access Journals (Sweden)

    Kwesi Amponsah-Tawiah

    2017-03-01

    Conclusion: The study demonstrates that compared with personal characteristics such as personality traits, work environment factors such as organizational politics have a stronger influence on the occurrence of workplace victimization.

  10. Political Shocks and Abnormal Returns During the Taiwan Crisis: An Event Study Analysis

    National Research Council Canada - National Science Library

    Steeves, Geoffrey

    2002-01-01

    .... Focusing on the 1996 Taiwan Crisis, by means of event study analysis, this paper attempts to determine the extent to which this political shock affected the Taiwanese, and surrounding Japanese stock markets...

  11. Reasons for Choosing the Teaching Profession and Beliefs about Teaching: A Study with Elementary School Teacher Candidates

    Science.gov (United States)

    Dündar, Sahin

    2014-01-01

    The purpose of the present study was to examine elementary school teacher candidates' motivations for choosing the teaching profession, beliefs about teaching, and satisfaction with the choice. Data were collected from 176 freshman elementary school teacher candidates at two public universities in Turkey. Results showed that the decision to choose…

  12. STUDYING OF 1917-1918 POLITICAL SITUATION IN BAKU IN SOVIET HISTORIOGRAPHY OF 1920S

    Directory of Open Access Journals (Sweden)

    Вагиф оглы Абышов

    2014-12-01

    Full Text Available The article analyzes the works of Soviet historians, who first turned to the study of the post-revolutionary political situation in Baku in the 1920s. Among them are S.E Sef, S.S. Shaumyan, G. Stein, etc. It is concluded that the aim of this authors was justification of Bolsheviks’ coming to power while neglecting the role of other political forces. This historiographical situation makes it necessary to identify different interpretations of the events related to the political situation in Baku in 1917−1918 in order to restore the objective picture of the past history of Azerbaijan.

  13. Political apathy amongst students: A case study of Nelson Mandela Metropolitan University

    Directory of Open Access Journals (Sweden)

    Ntsikelelo B. Breakfast

    2017-09-01

    Full Text Available The primary motivation for this research, in which a qualitative method was employed, was to examine political apathy amongst students at Nelson Mandela Metropolitan University. The secondary motivation was to question whether youth political apathy threatens the consolidation of democracy. The researchers arranged four focus groups at Nelson Mandela Metropolitan University. A purposive sampling technique was utilised. All 50 participants in the study were Nelson Mandela Metropolitan University undergraduate and postgraduate black students, with ages ranging from 21 to 35 years. The researchers encouraged participants to have maximum participation in the focus group deliberations. The researchers also made use of elite interviews in the study. The findings of this study suggest that political apathy does exist amongst students at Nelson Mandela Metropolitan University. Most of the participants in the focus groups indicated that young people in post-apartheid South Africa have no interest in politics.

  14. Social capital, political trust, and health locus of control: a population-based study.

    Science.gov (United States)

    Lindström, Martin

    2011-02-01

    To investigate the association between political trust in the Riksdag and lack of belief in the possibility to influence one's own health (external locus of control), taking horizontal trust into account. The 2008 public health survey in Skåne is a cross-sectional postal questionnaire study with a 55% participation rate. A random sample of 28,198 persons aged 18-80 years participated. Logistic regression models were used to investigate the associations between political trust in the Riksdag (an aspect of vertical trust) and lack of belief in the possibility to influence one's own health (external locus of control). The multiple regression analyses included age, country of birth, education, and horizontal trust in other people. A 33.7% of all men and 31.8% of all women lack internal locus of control. Low (external) health locus of control is more common in higher age groups, among people born outside Sweden, with lower education, low horizontal trust, low political trust, and no opinion concerning political trust. Respondents with not particularly strong political trust, no political trust at all and no opinion have significantly higher odds ratios of external locus of control throughout the multiple regression analyses. Low political trust in the Riksdag seems to be independently associated with external health locus of control.

  15. Individualism, conservatism, and radicalism as criteria for processing political beliefs: a parametric fMRI study.

    Science.gov (United States)

    Zamboni, Giovanna; Gozzi, Marta; Krueger, Frank; Duhamel, Jean-René; Sirigu, Angela; Grafman, Jordan

    2009-01-01

    Politics is a manifestation of the uniquely human ability to debate, decide, and reach consensus on decisions affecting large groups over long durations of time. Recent neuroimaging studies on politics have focused on the association between brain regions and specific political behaviors by adopting party or ideological affiliation as a criterion to classify either experimental stimuli or subjects. However, it is unlikely that complex political beliefs (i.e., "the government should protect freedom of speech") are evaluated only on a liberal-to-conservative criterion. Here we used multidimensional scaling and parametric functional magnetic resonance imaging to identify which criteria/dimensions people use to structure complex political beliefs and which brain regions are concurrently activated. We found that three independent dimensions explained the variability of a set of statements expressing political beliefs and that each dimension was reflected in a distinctive pattern of neural activation: individualism (medial prefrontal cortex and temporoparietal junction), conservatism (dorsolateral prefrontal cortex), and radicalism (ventral striatum and posterior cingulate). The structures we identified are also known to be important in self-other processing, social decision-making in ambivalent situations, and reward prediction. Our results extend current knowledge on the neural correlates of the structure of political beliefs, a fundamental aspect of the human ability to coalesce into social entities.

  16. Genome-wide association study identifies candidate genes for starch content regulation in maize kernels

    Directory of Open Access Journals (Sweden)

    Na Liu

    2016-07-01

    Full Text Available Kernel starch content is an important trait in maize (Zea mays L. as it accounts for 65% to 75% of the dry kernel weight and positively correlates with seed yield. A number of starch synthesis-related genes have been identified in maize in recent years. However, many loci underlying variation in starch content among maize inbred lines still remain to be identified. The current study is a genome-wide association study that used a set of 263 maize inbred lines. In this panel, the average kernel starch content was 66.99%, ranging from 60.60% to 71.58% over the three study years. These inbred lines were genotyped with the SNP50 BeadChip maize array, which is comprised of 56,110 evenly spaced, random SNPs. Population structure was controlled by a mixed linear model (MLM as implemented in the software package TASSEL. After the statistical analyses, four SNPs were identified as significantly associated with starch content (P ≤ 0.0001, among which one each are located on chromosomes 1 and 5 and two are on chromosome 2. Furthermore, 77 candidate genes associated with starch synthesis were found within the 100-kb intervals containing these four QTLs, and four highly associated genes were within 20-kb intervals of the associated SNPs. Among the four genes, Glucose-1-phosphate adenylyltransferase (APS1; Gene ID GRMZM2G163437 is known as an important regulator of kernel starch content. The identified SNPs, QTLs, and candidate genes may not only be readily used for germplasm improvement by marker-assisted selection in breeding, but can also elucidate the genetic basis of starch content. Further studies on these identified candidate genes may help determine the molecular mechanisms regulating kernel starch content in maize and other important cereal crops.

  17. Alain Touraine’s study on politics and democracy

    Directory of Open Access Journals (Sweden)

    P. S. Kanevskiy

    2015-01-01

    Full Text Available Current article analyzes the influence of Alain Touraine’s ideas and theories on discourse on contemporary sociology and political sociology. How do structural transformations of society, processes of social fragmentation and atomization influence the essence of democracy, public consciousness, interaction between citizens and the state? Such global questions pose difficult tasks for scholars, who need to revise and renew the traditional approaches to be able to respond to challenges of our time. Controversial and deep heritage of Alain Touraine doesn’t give answers to all questions, but it’s able to generate new kinds of discourse in sociological community and this is the reason it’s still valuable.

  18. Political Advertising: A Roadblock in Teaching Social Studies Students the Importance of Truthful Political Communication to a Democratic Society

    Science.gov (United States)

    Martinson, David L.

    2009-01-01

    The author contends that too much political advertising is a form of public relations "spin" in which the truth is sacrificed and the political process damaged as a result. The goal of much of this advertising too frequently focuses on transmitting "disinformation" that, while perhaps not technically a lie, is intended not to inform the public but…

  19. Political Cultural Ecology and the Study of Regions in Mexico

    Directory of Open Access Journals (Sweden)

    Fábregas Puig, Andrés

    2009-06-01

    Full Text Available This paper shows why Cultural Ecology, understood as a method to explore the relationships between the environment and cultural processes, has deeply influenced a whole generation of Mexican anthropologists as a result of the teachings of Ángel Palerm and Eric Wolf. The practical application of Steward’s theories to the processes of Mexican regional formation, linked to the use of hydraulic technologies as part of both adaptative cultural strategies and the political control of water in the process of food production, shows that Cultural Ecology, understood as cultural management of natural environments, as it happens with Economy, is designed and politically manipulated in the context of deeply unequal societies with unadaptative consequences.

    El artículo muestra por qué la ecología cultural, entendida como un método para indagar en las relaciones entre el medio ambiente y los procesos culturales ha arraigado en una generación de antropólogos mexicanos como consecuencia del magisterio de Ángel Palerm y Eric Wolf. La aplicación práctica de las teorías de Steward a los procesos de formación regional mexicana vinculados a usos políticos de tecnologías hidráulicas como parte, tanto de estrategias culturales de adaptación como de control político del agua en el proceso de producción de alimentos, ha puesto de manifiesto que la ecología cultural, entendida como manejo cultural de entornos naturales, al igual que la economía, es diseñada y manejada políticamente en el contexto de sociedades profundamente desiguales con consecuencias maladaptantes.

  20. Do Personality and Organizational Politics Predict Workplace Victimization? A Study among Ghanaian Employees.

    Science.gov (United States)

    Amponsah-Tawiah, Kwesi; Annor, Francis

    2017-03-01

    Workplace victimization is considered a major social stressor with significant implications for the wellbeing of employees and organizations. The aim of this study was to examine the influences of employees' personality traits and organizational politics on workplace victimization among Ghanaian employees. Using a cross-sectional design, data were collected from 631 employees selected from diverse occupations through convenience sampling. Data collection tools were standardized questionnaires that measured experiences of negative acts at work (victimization), the Big Five personality traits, and organizational politics. The results from hierarchical multiple regression analysis showed that among the personality traits neuroticism and conscientiousness had significant, albeit weak relationships with victimization. Organizational politics had a significant positive relationship with workplace victimization beyond employees' personality. The study demonstrates that compared with personal characteristics such as personality traits, work environment factors such as organizational politics have a stronger influence on the occurrence of workplace victimization.

  1. Imputation-based analysis of association studies: candidate regions and quantitative traits.

    Directory of Open Access Journals (Sweden)

    Bertrand Servin

    2007-07-01

    Full Text Available We introduce a new framework for the analysis of association studies, designed to allow untyped variants to be more effectively and directly tested for association with a phenotype. The idea is to combine knowledge on patterns of correlation among SNPs (e.g., from the International HapMap project or resequencing data in a candidate region of interest with genotype data at tag SNPs collected on a phenotyped study sample, to estimate ("impute" unmeasured genotypes, and then assess association between the phenotype and these estimated genotypes. Compared with standard single-SNP tests, this approach results in increased power to detect association, even in cases in which the causal variant is typed, with the greatest gain occurring when multiple causal variants are present. It also provides more interpretable explanations for observed associations, including assessing, for each SNP, the strength of the evidence that it (rather than another correlated SNP is causal. Although we focus on association studies with quantitative phenotype and a relatively restricted region (e.g., a candidate gene, the framework is applicable and computationally practical for whole genome association studies. Methods described here are implemented in a software package, Bim-Bam, available from the Stephens Lab website http://stephenslab.uchicago.edu/software.html.

  2. Popular political continuity in urban England, 1867-1918: the case studies of Bristol and Northampton

    OpenAIRE

    Kidd, Matthew

    2016-01-01

    This thesis examines the transition between working-class radicalism and labour politics in two provincial English constituencies, Bristol and Northampton, between 1867 and 1918. By combining local case studies with a textual analysis of empirical material and a conceptual approach to ideology, it offers fresh insights into popular political change in late nineteenth- and early twentieth-century Britain. \\ud \\ud Its central argument is that, contrary to the prevailing historiography on labour...

  3. Same menu, seperate tables : the institutionalist turn in political science and the study of European integration

    OpenAIRE

    Aspinwall, Mark D.; Schneider, Gerald

    2000-01-01

    Recent research on European integration has largely profited from the institutionalist turn in political science. Theoretical progress has, however, been hampered by the diverse understandings of this new research tradition. This paper tries to tackle the conceptual diversity in a positive way. We first analyze the neo-institutionalist turn in political science and European studies and then move on to a detailed analysis and comparison of the three competing approaches sociological, histori...

  4. The Rhetoric of Networked Publics. Studying Social Network Sites as Rhetorical Arenas for Political Talk

    OpenAIRE

    Vatnøy, Eirik

    2017-01-01

    As social network sites have become a central part of the modern media landscape, they have also become important arenas for political talk between citizens. The possibilities these new arenas offer for social interaction and public participation have generated what social theorists describe as a restructuring of publics into “networked publics”. Numerous studies and theories suggest how the emergence of networked publics influences political participation and democracy. Still, we...

  5. Optimization of Candidate Selection Using Naive Bayes: Case Study in Company X

    Science.gov (United States)

    Kadar, JA; Agustono, D.; Napitupulu, D.

    2018-01-01

    This research was conducted as a decision-making system, and an alternative solution to complete the candidate assessment for a particular position. The human resources (HR) section on company X is responsible and initiative in selecting candidates in accordance with the assessment of their superiors. Selection by using the method of filling out the manager’s assessment questionnaire on the candidate’s subordinate. Three (3) managers have been determined to assess the 11 candidates for subordinates. By using questionnaire of quality classification of human resources and formula naive bayes it will get result which finally grouped using criteria scale as final grouping. The HR department has also determined that what is received is that which meets criteria 5. The result is three (3) candidates who can be proposed as candidates for certain positions in company X, and have met all required calculations. Furthermore the candidate will be given to management as an alternative input data in the selection of candidates.

  6. Identifying candidate sites for crop biofortification in Latin America: case studies in Colombia, Nicaragua and Bolivia.

    Science.gov (United States)

    Zapata-Caldas, Emmanuel; Hyman, Glenn; Pachón, Helena; Monserrate, Fredy Alexander; Varela, Liliana Vesga

    2009-05-19

    Agricultural science can address a population's vitamin, amino acid and mineral malnutrition through biofortification - agronomy, plant breeding and biotechnology to develop crops with high nutrient contents. Biofortified crop varieties should be grown in areas with populations at risk of nutrient deficiency and in areas where the same crop is already grown and consumed. Information on the population at risk of nutrient deficiency is rarely available for sub-national administrative units, such as provinces, districts, and municipalities. Nor is this type of information commonly analyzed with data on agricultural production. This project developed a method to identify populations at risk of nutrient deficiency in zones with high crop production, places where biofortification interventions could be targeted. Nutrient deficiency risk data were combined with crop production and socioeconomic data to assess the suitability of establishing an intervention. Our analysis developed maps of candidate sites for biofortification interventions for nine countries in Latin America and the Caribbean. Results for Colombia, Nicaragua, and Bolivia are presented in this paper. Interventions in northern Colombia appear promising for all crops, while sites for bean biofortification are widely scattered throughout the country. The most promising sites in Nicaragua are found in the center-north region. Candidate sites for biofortification in Bolivia are found in the central part of the country, in the Andes Mountains. The availability and resolution of data limits the analysis. Some areas show opportunities for biofortification of several crops, taking advantage of their spatial coincidence. Results from this analysis should be confirmed by experts or through field visits. This study demonstrates a method for identifying candidate sites for biofortification interventions. The method evaluates populations at risk of nutrient deficiencies for sub-national administrative regions, and

  7. Discovery of novel biomarker candidates for liver fibrosis in hepatitis C patients: a preliminary study.

    Directory of Open Access Journals (Sweden)

    Bevin Gangadharan

    Full Text Available Liver biopsy is the reference standard for assessing liver fibrosis and no reliable non-invasive diagnostic approach is available to discriminate between the intermediate stages of fibrosis. Therefore suitable serological biomarkers of liver fibrosis are urgently needed. We used proteomics to identify novel fibrosis biomarkers in hepatitis C patients with different degrees of liver fibrosis.Proteins in plasma samples from healthy control individuals and patients with hepatitis C virus (HCV induced cirrhosis were analysed using a proteomics technique: two dimensional gel electrophoresis (2-DE. This technique separated the proteins in plasma samples of control and cirrhotic patients and by visualizing the separated proteins we were able to identify proteins which were increasing or decreasing in hepatic cirrhosis. Identified markers were validated across all Ishak fibrosis stages and compared to the markers used in FibroTest, Enhanced Liver Fibrosis (ELF test, Hepascore and FIBROSpect by Western blotting. Forty four candidate biomarkers for hepatic fibrosis were identified of which 20 were novel biomarkers of liver fibrosis. Western blot validation of all candidate markers using plasma samples from patients across all Ishak fibrosis scores showed that the markers which changed with increasing fibrosis most consistently included lipid transfer inhibitor protein, complement C3d, corticosteroid-binding globulin, apolipoprotein J and apolipoprotein L1. These five novel fibrosis markers which are secreted in blood showed a promising consistent change with increasing fibrosis stage when compared to the markers used for the FibroTest, ELF test, Hepascore and FIBROSpect. These markers will be further validated using a large clinical cohort.This study identifies 20 novel fibrosis biomarker candidates. The proteins identified may help to assess hepatic fibrosis and eliminate the need for invasive liver biopsies.

  8. Money and politics: The effects of campaign spending limits on political competition and incumbency advantage

    OpenAIRE

    Avis, Eric; do Amaral, Claudio A. Ferraz; Finan, Frederico S.; Varjão, Carlos

    2017-01-01

    This paper examines the effects of campaign spending limits on political competition and incumbency advantage. We study a reform in Brazil that imposed limits on campaign spending for mayoral elections. These limits were implemented with a discontinuous kink which we exploit for causal identification. We find that stricter limits increase political competition by creating a larger pool of candidates that is on average less wealthy. Moreover, we find that stricter spending limits reduce the in...

  9. Political balance

    DEFF Research Database (Denmark)

    Hopmann, David Nicolas; Van Aelst, Peter; Salgado, Susana

    2017-01-01

    Before every election campaign, the French Conseil supérieur de l’audiovisuel (CSA) publishes detailed rules on how much news coverage candidates are allowed to have vis-à-vis one another in the electronic media to ensure what it calls pluralisme politique (e.g., CSA 2011). Also outside election...... and control news coverage (mainly public broadcasters) or have informal rules that determine news coverage of politics (Hopmann, Van Aelst, and Legnante 2012; Kaid and Strömbäck 2008)....

  10. Social capital, political trust and self-reported psychological health: a population-based study.

    Science.gov (United States)

    Lindstrom, Martin; Mohseni, Mohabbat

    2009-02-01

    This study investigates the association between political trust (an aspect of institutional trust) in the Riksdag (the national parliament in Sweden) and self-reported psychological health, taking generalized (horizontal) trust in other people into account. The 2004 public health survey in Skåne in Southern Sweden is a cross-sectional postal questionnaire study that was answered by 27,757 respondents aged 18-80 yielding a 59% response rate. A logistic regression model was used to investigate the associations between political trust and self-reported psychological health adjusting for possible confounders (age, country of origin, education, economic stress and generalized trust in other people i.e. horizontal trust). We found that 13.0% of the men and 18.9% of the women reported poor psychological health. A total of 17.3% and 11.6% of the male and female respondents, respectively, reported that they had no trust at all in the national parliament, and another 38.2% and 36.2%, respectively, reported that their political trust was not particularly high. Respondents in younger age groups, born abroad, with high education, high levels of economic stress, low horizontal trust and low political trust had significantly higher levels of self-reported poor psychological health. There was a significant association between low political trust and low horizontal trust. After adjustments for age, country of origin, education and economic stress, the inclusion of horizontal trust reduced the odds ratios of self-reported poor psychological health in the "no political trust at all" category compared to the "very high political trust" category from 1.6 to 1.4 among men and from 1.7 to 1.4 among women. It is concluded that low political trust in the Riksdag seems to be significantly and positively associated with poor mental health.

  11. Generating political priority for regulatory interventions targeting obesity prevention: an Australian case study.

    Science.gov (United States)

    Baker, Phillip; Gill, Timothy; Friel, Sharon; Carey, Gemma; Kay, Adrian

    2017-03-01

    Effective obesity prevention requires a synergistic mix of population-level interventions including a strong role for government and the regulation of the marketing, labelling, content and pricing of energy-dense foods and beverages. In this paper we adopt the agenda of the Australian Federal Government (AFG) as a case study to understand the factors generating or hindering political priority for such 'regulatory interventions' between 1990 and 2011. Using a theoretically-guided process tracing method we undertook documentary analysis and conducted 27 interviews with a diversity of actors involved in obesity politics. The analysis was structured by a theoretical framework comprising four dimensions: the power of actors involved; the ideas the actors deploy to interpret and portray the issue; the institutional and political context; and issue characteristics. Despite two periods of sustained political attention, political priority for regulatory interventions did not emerge and was hindered by factors from all four dimensions. Within the public health community, limited cohesion among experts and advocacy groups hampered technical responses and collective action efforts. An initial focus on children (child obesity), framing the determinants of obesity as 'obesogenic environments', and the deployment of 'protecting kids', 'industry demonization' and 'economic costs' frames generated political attention. Institutional norms within government effectively selected out regulatory interventions from consideration. The 'productive power' and activities of the food and advertising industries presented formidable barriers, buttressed by a libertarian/neolibertarian rhetoric emphasizing individual responsibility, a negative view of freedom (as free from 'nanny-state' intervention) and the idea that regulation imposes an unacceptable cost on business. Issue complexity, the absence of a supportive evidence base and a strict 'evidence-based' policy-making approach were used as

  12. A qualitative study of politeness strategies used by Iranian EFL learners in a class blog

    Directory of Open Access Journals (Sweden)

    Seyyed Mohammad Reza Adel

    2016-01-01

    Full Text Available In regard to the significant role of information and communication technology (ICT in educational systems, it becomes increasingly important to gain a better understanding of the features of the language used by learners in the new contexts created by this medium. This paper aims at analyzing politeness strategies including negative politeness, positive politeness, bald on-record, and bald-off record strategies in posts written by Iranian EFL learners in a class blog as an opportunity for asynchronous interaction in response to their teachers and peers. The participants of the study were 14 Iranian EFL learners selected based on their level of language proficiency. There were 1520 politeness utterances across all posts including 800 politeness utterances used when learners were interacting with their instructor and 720 politeness utterances used when learners were interacting with their peers. The collected data were analyzed using content analysis as well as Computer-Mediated Discourse Analysis (CMDA. The results revealed that learners frequently used positive strategies as signs of psychologically close relationship, reciprocity and friendship in a group.

  13. Association study of candidate gene polymorphisms with amnestic mild cognitive impairment in a Chinese population.

    Directory of Open Access Journals (Sweden)

    Xiaoyan Liu

    Full Text Available To investigate the relationship between amnestic mild cognitive impairment (aMCI and candidate gene polymorphisms in a Chinese population, 116 aMCI patients and 93 normal controls were recruited. Multi-dimensional neuropsychological tests were used to extensively assess the cognitive functions of the subjects. MassARRAY and iPLEX systems were used to measure candidate single nucleotide polymorohisms (SNPs and analyse allelic, genotypic or haplotypic distributions. The scores of the neuropsychological tests were significantly lower for the aMCI patients than for the normal controls. The distributions of SNPs relating to the amyloid cascade hypothesis (TOMM40 rs157581 G and TOMM40 rs2075650 G, to the cholesterol metabolism hypothesis (ApoE rs429358 C, LDLR rs11668477 G and CH25H rs7091822 T and PLAU rs2227564 CT and to the tau hypothesis (MAPT/STH rs242562 GG in aMCI were significantly different than those in normal controls. Interactions were also found in aMCI amongst SNPs in LDLR rs11668477, PLAU rs2227564, and TOMM40 rs157581, between SNPs in TOMM40 rs157580 and BACE2 rs9975138. The study suggests that aMCI is characterised by memory impairment and associated with SNPs in three systems relating to the pathogenesis of AD--those of the amyloid cascade, tau and cholesterol metabolism pathways. Interactions were also observed between genes in the amyloid pathway and between the amyloid and cholesterol pathways.

  14. Is effective a prior multiparametric magnetic resonance scan in patients candidates to prostate biopsy? CAT Study.

    Science.gov (United States)

    Ramos Rodríguez, J R; Molinero Pérez, M; Herrera Imbroda, B; Domínguez Pinos, M D

    2016-01-01

    We carried out a critically appraised topic (CAT)-type study to determine whether the relevant scientific evidence supports the recommendation of doing a multiparametric magnetic resonance imaging study of the prostate in all patients who are candidates for prostate biopsy with the aim of improving the detection of clinically significant prostate cancer and stratifying patients to receive active surveillance or treatment. After a formal literature search and an analysis of the two most relevant articles it found, we reached the conclusion that, despite promising results that point to the potential usefulness of this approach, there is still not enough clear scientific evidence to endorse it categorically. Before this approach can be endorsed, we need evidence from well-designed prospective randomized trials using widely agreed upon criteria and including large numbers of patients at multiple centers. Copyright © 2016 SERAM. Published by Elsevier España, S.L.U. All rights reserved.

  15. Expression studies of the obesity candidate gene FTO in pig

    DEFF Research Database (Denmark)

    Madsen, Majbritt Busk; Birck, Malene Muusfeldt; Fredholm, Merete

    2010-01-01

    developmental stages. Expression of the FTO transcript was detected in all tissues tested with significantly higher levels in brain tissues (cortex, cerebellum, and hippocampus; P development and between the specific parts of the brain studied (i.e., frontal cortex......Obesity is an increasing problem worldwide and research on candidate genes in good animal models is highly needed. The pig is an excellent model as its metabolism, organ size, and eating habits resemble that of humans. The present study is focused on the characterization of the fat mass and obesity...... associated gene (FTO) in pig. This gene has recently been associated with increased body mass index in several human populations. To establish information on the expression profile of FTO in the pig we performed quantitative PCR in a panel of adult pig tissues and in tissues sampled at different...

  16. A Quantitative Review of the Empirical Studies on the Negative Political Advertising.

    Science.gov (United States)

    Lin, Yang

    A study quantitatively reviewed empirical studies of negative political advertising using a method that combined citation analysis and content analysis. The citation analysis examined each individual cited work in 20 selected studies with respect to its citation information, and the content analysis investigated the 20 selected studies (citing…

  17. 345 The Language of Satire in Nigerian Politics: A Study of the ...

    African Journals Online (AJOL)

    . This article examines how Wale Okediran deploys the language of political discourse replete with political features satirically in Tenants of the House to expose political corruption and the atrocities of Nigerian political leaders. In many of his.

  18. An Empirical Study of the Relationship between Performance Appraisal Politics and Job Satisfaction

    Directory of Open Access Journals (Sweden)

    Azman Ismail

    2011-02-01

    Full Text Available Performance appraisal politics are viewed as a vital human resource management issuewhere it consists of two salient features: motivational motive and punishment motive. The ability ofappraisers (e.g., immediate bosses/managers to properly implement such appraisal politics inallocating performance ratings may have significant impact on job satisfaction. Although the nature ofthis relationship is important, little is known about the role of performance appraisal politics as apredicting variable in the performance appraisal models. Therefore, this study was conducted toexamine the effect of performance appraisal politics on job satisfaction using 150 usablequestionnaires gathered from employees who have worked in a national postal company in Sarawak,Malaysia. In initial data analysis, the results of exploratory factor analysis confirmed that themeasurement scales used in this study satisfactorily met the standards of validity and reliabilityanalyses. Further, in hypothesis testing, the outcomes of stepwise regression analysis showed thatperformance appraisal politics (i.e., motivational motive and punishment motive significantlycorrelated with job satisfaction. Statistically, this result confirms that performance appraisal politicsact as important predictors of job satisfaction in the studied organization. In addition, discussion,implications and conclusion are elaborated.

  19. A Study on Teacher Candidates' Competencies in Classroom Management

    Science.gov (United States)

    Selçuk, Gülenaz; Kadi, Aysegül; Yildirim, Remzi; Çelebi, Nurhayat

    2017-01-01

    The objective of this paper is to examine competencies in classroom management of teacher candidates. Research design was determined as pre-experimental research design. Research was conducted with 388 teacher candidates. In this research, these were found; Attitudes of students about competencies in classroom management differ according to…

  20. From Kundun to Mulan: A Political Economic Case Study of Disney and China

    Directory of Open Access Journals (Sweden)

    Hongmei Yu

    2015-01-01

    Full Text Available This case study examines the Walt Disney Company’s foray in the Chinese market from a political economic perspective. It focuses on two film-related events: 1 the 'Kundun' incident in 1996 that displays the ideological confrontation between Disney and China in the post-Cold War era, and 2 the production of 'Mulan 'in 1998 as both a political compromise and a strategic marketing decision for Disney to regain the Chinese market. The conflicts and negotiations between Disney and China provide a telling example to study the local operation of global capitalism, especially in terms of its interaction with the state. While many believe that the advent of globalization will open more free markets for fair competition, this study reveals how government policy intervenes in the global entertainment industry, and sheds light on the political and economic struggles behind the silver screen.

  1. Theorising Media, Power and Politics in Discourse Theory and Framing Studies

    DEFF Research Database (Denmark)

    Dindler, Camilla; Roslyng, Mette Marie

    The development of digital media has profound consequences for social and political interaction and, therefore, a new radical interactivity also influences the way in which media can be theorised and analysed? (Couldry, 2012, p. 2). As pointed out by Hall (2006) and others, media discourse may...... either contribute to or challenge the current status quo. Likewise, media framing studies indicate that the media may play an independent political role in terms of raising, shaping and morally judging issues of civic relevance (Entman, 2004). Framing and discourse theory have overlapping as well...... as different trajectories in empirical studies of mediated political communication. Both perspectives bear upon constructivist and critical thinking concerning the role of media in society (Gitlin 1980) and previous studies of media content have even sometimes conflated the terms discourse and frame...

  2. Political action committee for scientists

    Science.gov (United States)

    Richman, Barbara T.

    Spurred by budget proposals that could severely reduce science funding (Eos, March 24, March 3, February 10), seven scientists currently serving as Congressional Science or State Department Fellows recently founded a political action committee (PAC) for scientists. The Science and Technology Political Action Committee (SCITEC-PAC) aims to make scientists more politically aware and better informed about potential legislative actions that affect research. It will also serve to ‘establish a political presence’ with respect to science, said Donald Stein, SCITEC-PAC's chairman.The organization is not a lobbying group, explained Stein, professor of neurology and psychology at Clark University and the University of Massachusetts Medical Center. ‘Lobbyists seek to influence officials by presenting information to them,’ he said, ‘while a PAC tries to influence the outcome of elections through campaign contributions of money, time, and effort in behalf of candidates that share similar goals and aspirations.’ In other words, the PAC will be a vehicle for promoting candidates for federal office who advocate strong support for scientific research and training. In addition, the PAC will develop and study science policy and budget issues and will attempt to stimulate government and private sector interest in these issues.

  3. Women's political participation and health: a health capability study in rural India.

    Science.gov (United States)

    Feldman, Candace H; Darmstadt, Gary L; Kumar, Vishwajeet; Ruger, Jennifer Prah

    2015-02-01

    Understanding the relationship between women's political participation and health has eluded researchers and cannot be adequately studied using traditional epidemiological or social scientific methodologies. We employed a health capability framework to understand dimensions of health agency to illuminate how local political economies affect health. Exploiting a cluster-randomized controlled trial of a community-based behavior change management intervention in northern India, we conducted a qualitative study with semistructured, in-depth focus groups in both intervention and nonintervention villages. We presented scenarios to each group regarding the limitations and motivations involved in women's political participation and health. Thematic analysis focused on four domains of health agency -- participation, autonomy, self-efficacy, and health systems -- relevant for understanding the relationship between political participation and health. Elder women demonstrated the greatest sense of self-efficacy and as a group cited the largest number of successful health advocacy efforts. Participation in an associated community-based neonatal intervention had varying effects, showing some differences in self-efficacy, but only rare improvements in participation, autonomy, or health system functioning. Better understanding of cultural norms surrounding autonomy, the local infrastructure and health system, and male and female perceptions of political participation and self-efficacy are needed to improve women's health agency. For a community-based participatory health intervention to improve health capability effectively, explicit strategies focused on health agency should be as central as health indicators. Copyright © 2015 by Duke University Press.

  4. Genome association study through nonlinear mixed models revealed new candidate genes for pig growth curves

    Directory of Open Access Journals (Sweden)

    Fabyano Fonseca e Silva

    Full Text Available ABSTRACT: Genome association analyses have been successful in identifying quantitative trait loci (QTLs for pig body weights measured at a single age. However, when considering the whole weight trajectories over time in the context of genome association analyses, it is important to look at the markers that affect growth curve parameters. The easiest way to consider them is via the two-step method, in which the growth curve parameters and marker effects are estimated separately, thereby resulting in a reduction of the statistical power and the precision of estimates. One efficient solution is to adopt nonlinear mixed models (NMM, which enables a joint modeling of the individual growth curves and marker effects. Our aim was to propose a genome association analysis for growth curves in pigs based on NMM as well as to compare it with the traditional two-step method. In addition, we also aimed to identify the nearest candidate genes related to significant SNP (single nucleotide polymorphism markers. The NMM presented a higher number of significant SNPs for adult weight (A and maturity rate (K, and provided a direct way to test SNP significance simultaneously for both the A and K parameters. Furthermore, all significant SNPs from the two-step method were also reported in the NMM analysis. The ontology of the three candidate genes (SH3BGRL2, MAPK14, and MYL9 derived from significant SNPs (simultaneously affecting A and K allows us to make inferences with regards to their contribution to the pig growth process in the population studied.

  5. THE MAIN DIRECTIONS IN THE STUDY OF POLITICAL ELITES IN THE POST-CLASSICAL ITALIAN POLITICAL SCIENCE

    Directory of Open Access Journals (Sweden)

    Кирилл Сергеевич Кондрашев

    2013-07-01

    Full Text Available PurposeDetection the main approaches to the definition of the political elites, their appearance and function in a democracy.Methodology of workThe comparative method, structural and functional method.ResultsMarked changes in the methods of communication elites and masses, the emergence of new types of elites that meet the transforming needs of the masses, changing the structure of the political sphere in terms of postmodernism and globalization.Application of resultsThe results can be applied in the process policy advice.DOI: http://dx.doi.org/10.12731/2218-7405-2013-5-27

  6. Internet and politics studies in Brazil: mapping the characteristics and disparities of the research field

    Directory of Open Access Journals (Sweden)

    Maria Alejandra Nicolás

    2013-08-01

    Full Text Available This article focuses on the appropriation of the subject of Internet and Politics by Brazilian Social Sciences. To this end, we analysed 299 papers presented at 11 conferences in the areas of Sociology, Political Science and Social Communication from 2000 to 2011 in Brazil. The methodology was based on content analysis in order to map the main authors, research centres, political and technological objects, theoretical approaches, methods, techniques and coverage areas of the papers presented in each of these conferences. Our findings suggest significant growth in the number of studies presented over the last few years, where 40.5% were based mainly on qualitative research and 56.5% had an emphasis on the civil society strand. Finally, our longitudinal analyses indicate some changes in the field, with a growing number of studies carrying out empirical research, and a tendency to focus on more specific digital tools instead of on the Internet in general.

  7. Political Terrorism: An Historical Case Study of the Italian Red Brigade

    Directory of Open Access Journals (Sweden)

    Major Victor H. Sundquist

    2010-01-01

    Full Text Available As the world's governments become increasingly engulfed in economic and political strife, international leaders should step back and understand what historical realities enabled political extremism to surface in particular regions of the world. More important, these leaders need to recognize what past governments did to counter these movements. Global communities are currently witnessing a dynamic trend of populous uprisings that in some cases, like Greece and the United States, have the potential to severely disrupt the activities of local governments. Consequently, it behooves leaders to reflect upon historical precedence in order to avoid repeating the same mistakes of our forefathers. Accordingly, the rise and fall of the Italian Red Brigades represents a classic case study from which to understand the dynamics behind the development of a political terrorist organization and its effects on society as a whole.

  8. The Candidate

    OpenAIRE

    Osborn, John C

    2013-01-01

    ABSTRACT   The Candidate is an attempt to marry elements of journalism and gaming into a format that both entertains and educates the player. The Google-AP Scholarship, a new scholarship award that is given to several journalists a year to work on projects at the threshold of technology and journalism, funded the project. The objective in this prototype version of the game is to put the player in the shoes of a congressional candidate during an off-year election, specificall...

  9. Methods study of homogeneity and stability test from cerium oxide CRM candidate

    International Nuclear Information System (INIS)

    Samin; Susanna TS

    2016-01-01

    The methods study of homogeneity and stability test from cerium oxide CRM candidate has been studied based on ISO 13258 and KAN DP. 01. 34. The purpose of this study was to select the test method homogeneity and stability tough on making CRM cerium oxide. Prepared 10 sub samples of cerium oxide randomly selected types of analytes which represent two compounds, namely CeO 2 and La 2 O 3 . At 10 sub sample is analyzed CeO 2 and La 2 O 3 contents in duplicate with the same analytical methods, by the same analyst, and in the same laboratory. Data analysis results calculated statistically based on ISO 13528 and KAN DP.01.34. According to ISO 13528 Cerium Oxide samples said to be homogeneous if Ss ≤ 0.3 σ and is stable if | Xr – Yr | ≤ 0.3 σ. In this study, the data of homogeneity test obtained CeO 2 is Ss = 2.073 x 10-4 smaller than 0.3 σ (0.5476) and the stability test obtained | Xr - Yr | = 0.225 and the price is < 0.3 σ. Whereas for La 2 O 3 , the price for homogeneity test obtained Ss = 1.649 x 10-4 smaller than 0.3 σ (0.4865) and test the stability of the price obtained | Xr - Yr | = 0.2185 where the price is < 0.3 σ. Compared with the method from KAN, a sample of cerium oxide has also been homogenized for Fcalc < Ftable and stable, because | Xi - Xhm | < 0.3 x n IQR. Provided that the results of the evaluation homogeneity and stability test from CeO 2 CRM candidate test data were processed using statistical methods ISO 13528 is not significantly different with statistical methods from KAN DP.01.34, which together meet the requirements of a homogeneous and stable. So the test method homogeneity and stability test based on ISO 13528 can be used to make CRM cerium oxide. (author)

  10. 7 CFR 7.27 - Political activity.

    Science.gov (United States)

    2010-01-01

    ... (including the sale of tickets) for political party organizations or for a candidate for political office or... money, pledges, gifts, or anything of value (including the sale of tickets) made for: (1) Political... contributions (including the buying or the refusal to buy tickets) for political purposes, or for supporting or...

  11. Politics and the New African Novel: A Study of the Fiction of Francis Bebey

    Directory of Open Access Journals (Sweden)

    W. Curtis Schade

    1980-01-01

    Full Text Available From its inception African fiction has been strongly marked by political themes. In the late 1950's the virulent satire of Mongo Béti and Ferdinand Oyono stated the case against the denigration of African values inherent in all aspects of the colonial system. Their style and message subsequently gave way to novels focusing upon the drama of the transition of power at the moment of Independence. Whether optimistic or disillusioned, many of these novels featured real events and people, often thinly disguised, and sought to give an «inside» picture of that historical moment. Other tendencies developed in the late 60's, most notably a strongly autocritical, often radical, body of fiction represented by such writers as Ousmane Sembène and Alioum Fangouré, and the more distant, philosophical study of politics and society of writers like Ahmadou Kourouma. In all of these examples the contemporary political situation, whether viewed globally or as it affected the life of a simple man, was the primary moving force within the novel. By contrast, this paper will concentrate upon the work of Francis Bebey, exemplary of another current trend, fiction which, while continuing to deal with political concerns, does so in a different light, creating different tones, using different techniques. In the three novels and one short-story studied, politics is subordinated to other concerns and is treated less reverently than heretofore. We see in the work of Bebey a re-assessment of politics and its place in the life of contemporary (African man.

  12. Candidate molecular markers of hygienic behavior in honeybees (Apis mellifera: an expression study.

    Directory of Open Access Journals (Sweden)

    Francesca Dell'Orco

    2016-06-01

    The differential expression analysis of the candidate markers, performed after selection of the normalizing gene through geNorm and NormFinder algorithms, highlighted a correlation of OBP4 and ACT5C expression level with HB score.

  13. The emergence of maternal health as a political priority in Madhya Pradesh, India: a qualitative study.

    Science.gov (United States)

    Jat, Tej Ram; Deo, Prakash Ramchandra; Goicolea, Isabel; Hurtig, Anna-Karin; San Sebastian, Miguel

    2013-09-30

    Politics plays a critical role in agenda setting in health affairs; therefore, understanding the priorities of the political agenda in health is very important. The political priority for safe motherhood has been investigated at the national level in different countries. The objective of this study was to explore why and how maternal health became a political priority at sub-national level in the state of Madhya Pradesh in India. This study followed a qualitative design. Data were collected by carrying out interviews and review of documents. Semi-structured interviews were carried out with twenty respondents from four stakeholder groups: government officials, development partners, civil society and academics. Data analysis was performed using thematic analysis. The analysis was guided by Kingdon's multiple streams model. The emergence of maternal health as a political priority in Madhya Pradesh was the result of convergence in the developments in different streams: the development of problem definition, policy generation and political change. The factors which influenced this process were: emerging evidence of the high magnitude of maternal mortality, civil society's positioning of maternal mortality as a human rights violation, increasing media coverage, supportive policy environment and launch of the National Rural Health Mission (NRHM), the availability of effective policy solutions, India's aspiration of global leadership, international influence, maternal mortality becoming a hot debate topic and political transition at the national and state levels. Most of these factors first became important at national level which then cascaded to the state level. Currently, there is a supportive policy environment in the state for maternal health backed by greater political will and increased resources. However, malnutrition and population stabilization are the competing priorities which may push maternal health off the agenda. The influence of the events and factors

  14. The emergence of maternal health as a political priority in Madhya Pradesh, India: a qualitative study

    Science.gov (United States)

    2013-01-01

    Background Politics plays a critical role in agenda setting in health affairs; therefore, understanding the priorities of the political agenda in health is very important. The political priority for safe motherhood has been investigated at the national level in different countries. The objective of this study was to explore why and how maternal health became a political priority at sub-national level in the state of Madhya Pradesh in India. Methods This study followed a qualitative design. Data were collected by carrying out interviews and review of documents. Semi-structured interviews were carried out with twenty respondents from four stakeholder groups: government officials, development partners, civil society and academics. Data analysis was performed using thematic analysis. The analysis was guided by Kingdon’s multiple streams model. Results The emergence of maternal health as a political priority in Madhya Pradesh was the result of convergence in the developments in different streams: the development of problem definition, policy generation and political change. The factors which influenced this process were: emerging evidence of the high magnitude of maternal mortality, civil society’s positioning of maternal mortality as a human rights violation, increasing media coverage, supportive policy environment and launch of the National Rural Health Mission (NRHM), the availability of effective policy solutions, India’s aspiration of global leadership, international influence, maternal mortality becoming a hot debate topic and political transition at the national and state levels. Most of these factors first became important at national level which then cascaded to the state level. Currently, there is a supportive policy environment in the state for maternal health backed by greater political will and increased resources. However, malnutrition and population stabilization are the competing priorities which may push maternal health off the agenda. Conclusions

  15. A Critique of Contemporary Approaches to the Study of Political Communication.

    Science.gov (United States)

    Sanders, Keith R.

    The twentieth century history of the academic study of political communication can be divided into three parts: the period between the World Wars, the period 1940-1965, and the period from 1965 to the present. In the first period, social scientists were greatly concerned that the democratic process might be subverted by propaganda; they were…

  16. Hiroshima: A Study in Science, Politics and the Ethics of War. Teacher and Student Manuals.

    Science.gov (United States)

    Harris, Jonathan

    By focusing on the question of whether it was right or wrong to drop the atomic bomb on Hiroshima, this social studies unit seeks to illuminate the political, military, scientific, and moral complexities involved in making far-reaching decisions today. Sections of the unit use primary materials from American, Japanese, and English sources to…

  17. How body balance influences political party evaluations: A wii balance board study

    NARCIS (Netherlands)

    K. Dijkstra (Katinka); A. Eerland (Anita); J.M. Zijlmans (Mark); L.S. Post (Lysanne)

    2012-01-01

    textabstractEmbodied cognition research has shown how actions or body positions may affect cognitive processes, such as autobiographical memory retrieval or judgments. The present study examined the role of body balance (to the left or the right) in participants on their attributions to political

  18. Audience studies 2.0: on the theory, politics and method of qualitative audience research

    NARCIS (Netherlands)

    Hermes, J.

    2009-01-01

    Audience research, this paper suggests, is an excellent field to test the claims of Media Studies 2.0. Moreover, 2.0 claims are a good means to review qualitative audience research itself too. Working from a broad strokes analysis of the theory, politics and method of interpretative research with

  19. Political Engagement during a Presidential Election Year: A Case Study of Media Literacy Students

    Science.gov (United States)

    Powers, Elia; Moeller, Susan; Yuan, Yacong

    2016-01-01

    This exploratory, mixed-methods study uses data gathered during the previous U.S. presidential election in 2012 to evaluate student political engagement and digital culture. Survey results and media diary entries revealed that college students enrolled in a media literacy course during Super Tuesday or Election Day gravitated toward low-barrier…

  20. Citation Behavior of Undergraduate Students: A Study of History, Political Science, and Sociology Papers

    Science.gov (United States)

    Hendley, Michelle

    2012-01-01

    The goal of this analysis was to obtain local citation behavior data on undergraduates researching history, political science, and sociology papers. The study found that students cited books and journals even with the availability of web sources; however, usage varied by subject. References to specific websites' domains also varied across subject…

  1. State Constitutionalism: Completing the Interdisciplinary Study of Constitutional Law and Political Theory.

    Science.gov (United States)

    Williams, Robert F.

    1993-01-01

    Argues that a complete and accurate understanding of constitutional history and constitutional law requires the study of state constitutions. Maintains that state constitutions contain a coherent political theory that is, in important respects, at variance with the concept of federalism. (CFR)

  2. Political skill construct and criterion-related validation: A two-study investigation

    DEFF Research Database (Denmark)

    Ferris, G.R.; Blickle, G.; Schneider, P.B.

    2008-01-01

    made to also identify a single, higher-order factor solution through second-order factor analysis. The present research aims to expand on prior work and report on a two-study investigation of both the construct validity and antecedents and consequences of the political skill construct. Design...

  3. 5 CFR 734.411 - Participation in political campaigning; prohibitions.

    Science.gov (United States)

    2010-01-01

    ... under this subpart may not: (a) Take an active part in managing the political campaign of a candidate for partisan political office or a candidate for political party office; (b) Campaign for partisan... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Participation in political campaigning...

  4. 5 CFR 734.205 - Participation in political campaigns.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Participation in political campaigns. 734... in political campaigns. Subject to the prohibitions in § 734.306, an employee may: (a) Display... candidate or a candidate for political party office in a political advertisement, broadcast, campaign...

  5. The limited role of myocardial fluorine-18 fluorodeoxyglucose imaging in candidates for cardiac transplantation. A planar imaging study

    International Nuclear Information System (INIS)

    Kalff, V.; Van Every, B.; Kelly, M.J.; Barton, H.J.; Bergin, P.J.; Esmore, D.S.; Berlangieri, S.U.

    1998-01-01

    This study compares the incidence and extent of hibernating myocardium (defined by myocardial perfusion/metabolism mismatch) in 28 cardiac transplant candidates with ischaemic cardiomyopathy and in 16 other patients with coronary artery disease (CAD) undergoing viability assessment. It then reviews the impact of myocardial perfusion metabolism imaging on management decisions in the transplant candidates at 6 months after scintigraphy. Each patient underwent a planar myocardial thallium-201 and fluorine-18 fluorodeoxyglucose scan on a modified gamma camera. Perfusion/metabolism mismatch was sized semi-quantitatively and each patient was assigned a global mismatch score. Transplant candidates had a lower left ventricular ejection fraction (LVEF) (P<0.0002) and extent of hibernating myocardium (lower global mismatch score: P=0.005) than other CAD patients but the difference in respect of mismatch frequency (8/28 vs 9/16 patients) did not reach statistical significance. Transplant candidates with LVEF <20% had a lower global mismatch score (P<0.02) than those with an LVEF ≥20%. Interestingly, two of three other CAD patients with LVEF <20% had a moderate mismatch. Follow-up studies revealed the lack of impact of metabolic imaging as none of the three transplant candidates who eventually underwent revascularisation had hibernating myocardium and transplantation was offered to one of only two candidates with more than one minor mismatch. Thus metabolic imaging in potential transplant candidates may be of limited value because of the very low extent of hibernating myocardium, particularly if LVEF is below 20% and where clinical decisions are often based on many other factors. (orig.)

  6. A Study of Curriculum Literacy and Information Literacy Levels of Teacher Candidates in Department of Social Sciences Education

    Science.gov (United States)

    Sural, Serhat; Dedebali, Nurhak Cem

    2018-01-01

    The present study aims to investigate information literacy and curriculum literacy levels of teacher candidates and to identify the relationship between them through their course of study at Faculty of Education. The research model was designed as quantitative one and general screening model was employed. The study group is 895 students, who were…

  7. Political Crowdfunding as concept of political technologies

    Directory of Open Access Journals (Sweden)

    Valeria GOLKA

    2016-09-01

    Full Text Available Political crowdfunding is analyzed as a new concept of political science. The justification of use of crowdfunding technologies not only in business but also in the political sphere is argued. The efficiency, availability, low cost of the new forms of political investment through the development of information and communication technologies are noted. The typology of political crowdfunding is proposed. Political projects promoting domestic crowdfunding platforms are analyzed. Attention is drawn to the problem of legal gaps in the regulation of crowdfunding is studied. The foreign experience of organizing public support (mikroinvestment political projects. It is emphasized that in terms of political theory crowdfunding is based on solidarity. The crowdfunding properties of transforming social capital accumulated by social networks into financial capital are mentioned.

  8. Preparation, homogeneity and stability studies of a candidate LRM for Se speciation

    Energy Technology Data Exchange (ETDEWEB)

    Bodo, Erzsebet Tuende; Stefanka, Zsolt; Ipolyi, Ildiko; Soeroes, Csilla; Dernovics, Mihaly; Fodor, Peter [Department of Applied Chemistry, Faculty of Food Science, Szent Istvan University, Villanyi ut 29-33, 1118, Budapest (Hungary)

    2003-09-01

    A laboratory reference material (LRM) was prepared from Brazil nuts (Bertholletia excelsa) for quality control (QC) purposes of selenium speciation. The preparation of this LRM led through the usual operation steps applied during routine reference material production from biota samples - preparation of the raw material, homogenisation, storage design, checking of homogeneity, microbiological status and possible irradiation effects, and monitoring the species stability vs time at different storage temperatures. The selenium speciation studies to check species stability were carried out on a HPLC-UV-HG-AFS measurement set-up. Special attention was paid to the correct identification of selenium species by applying independent HPLC separation techniques (ion-pairing and anion-exchange chromatography). The concentration of selenomethionine (SeMet) and total Se content were quantified (79.9 {mu}g g{sup -1} (calculated as Se) and 82.9 {mu}g g{sup -1}, respectively). The homogeneity and stability of this candidate reference material passed the relevant tests recommended by Bureau Communautaire de Reference (BCR). (orig.)

  9. A comparative study of candidal invasion in rabbit tongue mucosal explants and reconstituted human oral epithelium.

    Science.gov (United States)

    Jayatilake, J A M S; Samaranayake, Y H; Samaranayake, L P

    2008-06-01

    The purpose of this study is to compare the light and scanning electron microscopic (SEM) features of tissue invasion by three Candida species (C. albicans, C. tropicalis, and C. dubliniensis) in two different tissue culture models: rabbit tongue mucosal explants (RTME) and reconstituted human oral epithelium (RHOE). Tongue mucosal biopsies of healthy New Zealand rabbits were maintained in explant culture using a transwell system. RHOE was obtained from Skinethic Laboratory (Nice, France). RTME and RHOE were inoculated with C. albicans, C. tropicalis, and C. dubliniensis separately and incubated at 37 degrees C, 5% CO(2), and 100% humidity up to 48 h. Light microscopic and SEM examinations of uninfected (controls) and infected tissues were performed at 24 and 48 h. C. albicans produced characteristic hallmarks of pathological tissue invasion in both tissue models over a period of 48 h. Hyphae penetrated through epithelial cells and intercellular gaps latter resembling thigmotropism. SEM showed cavitations on the epithelial cell surfaces particularly pronounced at sites of hyphal invasion. Some hyphae on RTME showed several clusters of blastospores attached in regular arrangements resembling "appareil sporifere". C. tropicalis and C. dubliniensis produced few hyphae mainly on RTME but they did not penetrate either model. Our findings indicate that multiple host-fungal interactions such as cavitations, thigmotropism, and morphogenesis take place during candidal tissue invasion. RTME described here appears to be useful in investigations of such pathogenic processes of Candida active at the epithelial front.

  10. The influence of the political environment and destination governance on sustainable tourism development: a study of Bled, Slovenia

    OpenAIRE

    Mihalič, Tanja; Segota, Tina; Knežević Cvelbar, Ljubica; Kuščer, Kir

    2016-01-01

    In the context of sustainable tourism development, there are many studies about the exchange process between residents and tourism, yet this issue is practically unexplored with respect to the political environment of tourism. Therefore, this paper introduces and posits that the political environment is a necessary enabler for implementing sustainable tourism. The authors extend the established three-pillar sustainability concept by adding in the political dimension. Then they surveyed how re...

  11. How body balance influences political party evaluations: a wii balance board study.

    Science.gov (United States)

    Dijkstra, Katinka; Eerland, Anita; Zijlmans, Josjan; Post, Lysanne S

    2012-01-01

    Embodied cognition research has shown how actions or body positions may affect cognitive processes, such as autobiographical memory retrieval or judgments. The present study examined the role of body balance (to the left or the right) in participants on their attributions to political parties. Participants thought they stood upright on a Wii(™) Balance Board, while they were actually slightly tilted to the left or the right. Participants then ascribed fairly general political statements to one of 10 political parties that are represented in the Dutch House of Representatives. Results showed a significant interaction of congruent leaning direction with left- or right-wing party attribution. When the same analyses were performed with the political parties being divided into affiliations to the right, center, and left based on participants' personal opinions rather than a ruling classification, no effects were found. The study provides evidence that conceptual metaphors are activated by manipulating body balance implicitly. Moreover, people's judgments may be colored by seemingly trivial circumstances such as standing slightly out of balance.

  12. How body balance influences political party evaluations. A Wii balance board study.

    Directory of Open Access Journals (Sweden)

    Katinka eDijkstra

    2012-12-01

    Full Text Available Embodied cognition research has shown how actions or body positions may affect cognitive processes, such as autobiographical memory retrieval or judgments. The present study examined the role of body balance (to the left or the right in participants on their attributions to political parties. Participants thought they stood upright on a Wii™ Balance Board, while they were actually slightly tilted to the left or the right. Participants then ascribed fairly general political statements to one of ten political parties that are represented in the Dutch House of Representatives. Results showed a significant interaction of congruent leaning direction with left- or right wing party attribution. When the same analyses were performed with the political parties being divided into affiliations to the right, center, and left based on participants’ personal opinions rather than a ruling classification, no effects were found. The study provides evidence that conceptual metaphors are activated by manipulating body balance implicitly. Moreover, people’s judgments may be colored by seemingly trivial circumstances such as standing slightly out of balance.

  13. Corrosion susceptibility study of candidate pin materials for ALTC (Active Lithium/Thionyl Chloride) batteries

    Science.gov (United States)

    Bovard, Francine S.; Cieslak, Wendy R.

    1987-09-01

    The corrosion susceptibilities of eight alternate battery pin material candidates for ALTC (Active Lithium/Thionyl Chloride) batteries in 1.5M LiAlCl4/SOCl2 electrolyte have been investigated using ampule exposure and electrochemical tests. The thermal expansion coefficients of these candidate materials are expected to match Sandia-developed Li-corrosion resistant glasses. The corrosion resistances of the candidate materials, which included three stainless steels (15-5 PH, 17-4 PH, and 446), three Fe-Ni glass sealing alloys (Kovar, Alloy 52, and Niromet 426), a Ni-based alloy (Hastelloy B-2) and a zirconium-based alloy (Zircaloy), were compared to the reference materials Ni and 316L SS. All of the candidate materials showed some evidence of corrosion and, therefore, did not perform as well as the reference materials. The Hastelloy B-2 and Zircaloy are clearly unacceptable materials for this application. Of the remaining alternate materials, the 446 SS and Alloy 52 are the most promising candidates.

  14. Candidal carriage predicts candidiasis during topical immunosuppressive therapy: a preliminary retrospective cohort study.

    Science.gov (United States)

    Tejani, Sara; Sultan, Ahmed; Stojanov, Ivan; Woo, Sook-Bin

    2016-10-01

    To determine (1) the prevalence of candidal carriage in patients with oral mucosal disease to be treated with topical immunosuppressive therapy, and (2) the incidence of oral candidiasis among carriers and noncarriers after initiation of therapy to assess any correlation between carriage and the development of candidiasis. Records of patients who underwent swab cultures for Candida between January 2009 and October 2014 at the Brigham and Women's Hospital in Boston, Massachusetts, were retrospectively reviewed. The prevalence of candidal carriage and incidence of candidiasis were determined by using descriptive statistics. Of 99 evaluable patients, 20 (20.2%) were Candida positive and 79 (79.8%) were Candida negative. Of 44 patients with follow-up, 7 (15.9%) were Candida positive and 37 (84.1%) were Candida negative; five (11.4%) developed candidiasis. Four of seven (57.1%) Candida-positive patients developed candidiasis, whereas only one of 37 (2.7%) Candida-negative patients developed candidiasis (P = .0012). The overall prevalence of candidal carriage was low (20.2%), and there was a significant difference in the incidence of candidiasis between carriers and noncarriers (P = .0012) after topical immunosuppressive therapy. Therefore, patients who are candidal carriers should be monitored closely for the development of secondary candidiasis and may be candidates for prophylactic antifungal therapy. Copyright © 2016 Elsevier Inc. All rights reserved.

  15. Genome-wide and candidate gene association study of cigarette smoking behaviors.

    Directory of Open Access Journals (Sweden)

    Neil Caporaso

    Full Text Available The contribution of common genetic variation to one or more established smoking behaviors was investigated in a joint analysis of two genome wide association studies (GWAS performed as part of the Cancer Genetic Markers of Susceptibility (CGEMS project in 2,329 men from the Prostate, Lung, Colon and Ovarian (PLCO Trial, and 2,282 women from the Nurses' Health Study (NHS. We analyzed seven measures of smoking behavior, four continuous (cigarettes per day [CPD], age at initiation of smoking, duration of smoking, and pack years, and three binary (ever versus never smoking, 10 cigarettes per day [CPDBI], and current versus former smoking. Association testing for each single nucleotide polymorphism (SNP was conducted by study and adjusted for age, cohabitation/marital status, education, site, and principal components of population substructure. None of the SNPs achieved genome-wide significance (p<10(-7 in any combined analysis pooling evidence for association across the two studies; we observed between two and seven SNPs with p<10(-5 for each of the seven measures. In the chr15q25.1 region spanning the nicotinic receptors CHRNA3 and CHRNA5, we identified multiple SNPs associated with CPD (p<10(-3, including rs1051730, which has been associated with nicotine dependence, smoking intensity and lung cancer risk. In parallel, we selected 11,199 SNPs drawn from 359 a priori candidate genes and performed individual-gene and gene-group analyses. After adjusting for multiple tests conducted within each gene, we identified between two and five genes associated with each measure of smoking behavior. Besides CHRNA3 and CHRNA5, MAOA was associated with CPDBI (gene-level p<5.4x10(-5, our analysis provides independent replication of the association between the chr15q25.1 region and smoking intensity and data for multiple other loci associated with smoking behavior that merit further follow-up.

  16. Event-related potential evidence suggesting voters remember political events that never happened.

    Science.gov (United States)

    Coronel, Jason C; Federmeier, Kara D; Gonsalves, Brian D

    2014-03-01

    Voters tend to misattribute issue positions to political candidates that are consistent with their partisan affiliation, even though these candidates have never explicitly stated or endorsed such stances. The prevailing explanation in political science is that voters misattribute candidates' issue positions because they use their political knowledge to make educated but incorrect guesses. We suggest that voter errors can also stem from a different source: false memories. The current study examined event-related potential (ERP) responses to misattributed and accurately remembered candidate issue information. We report here that ERP responses to misattributed information can elicit memory signals similar to that of correctly remembered old information--a pattern consistent with a false memory rather than educated guessing interpretation of these misattributions. These results suggest that some types of voter misinformation about candidates may be harder to correct than previously thought.

  17. Factors Affecting the Participation of Social Studies Teacher Candidates in Discussions on Controversial Issues

    Directory of Open Access Journals (Sweden)

    A. Figen ERSOY

    2013-05-01

    about culturally and socially sensitive issues. 40.5% pre-service teachers in the study shared that they do not have discussions with their peers who are not tolerant to different ideas and perspectives. On the other hand, 48.7% participants argued that if the discussions become a personal battles between peers, they are not comfortable sharing their ideas. 54.8% of the participants stated that even if they feel like the teacher supports one of group against other groups, they still are comfortable expressing themselves during classroom discussions; however, 32.8% participants pointed out that they do not participate in the discussions if they believe the teacher is not objective about the sensitive issue.The findings of the study show that participants’ gender, income, their parents’ education, residency, the university they attend, grade level, and high school they graduated from are contributed to their level of participation in the classroom discussions about controversial issues. Female participants stated that if they feel like they do not have enough knowledge about the discussion topic or the topic is a culturally and socially sensitve issue, they either do not participate at all or their participation is limited. However, male pre-service teachers shared that they are more concerned about peer interaction and having good relationships with their peers after the discussion is ended as well. Another finding of the study indicate that pre-service teachers from low socio-economic status shared that if they feel like the teacher’s judgement might be compromised based on students’ contradicted ideas, they rarely participate in the discussions. In addition, students whose parents have limited education (i.e., elementary level said that they have difficulty expressing themselves during classroom discussions. Furthermore, another finding show that teacher candidates who come from big cities feel more comfortable participating in the classroom discussions about

  18. Association study of candidate genes for susceptibility to schizophrenia and bipolar disorder on chromosome 22Q13

    DEFF Research Database (Denmark)

    Severinsen, Jacob; Binderup, Helle; Mors, Ole

    , in which a missense mutation recently has been suggested to cause catatonic schizophrenia in a German family. The selected candidate genes were analyzed by a combination of database search and direct sequencing in a subset of the patients from the Faroe Islands in order to identify SNPs in the coding......Chromosome 22q is suspected to harbor risk genes for schizophrenia as well as bipolar affective disorder. This is evidenced through genetic mapping studies, investigations of cytogenetic abnormalities, and direct examination of candidate genes. In a recent study of distantly related patients from...... the Faroe Islands we have obtained evidence suggesting two regions on chromosome 22q13 to potentially harbor susceptibility genes for both schizophrenia and bipolar affective disorder. We have selected a number of candidate genes from these two regions for further analysis, including the neuro-gene WKL1...

  19. Hmong Political Involvement in St. Paul, Minnesota and Fresno, California

    Directory of Open Access Journals (Sweden)

    Yang Lor

    2010-01-01

    Full Text Available Over the past several years, Hmong in the United States have gained prominence for their increasing involvement in politics. Most of the attention has understandably focused on Fresno, California and St. Paul, Minnesota, home to the two largest Hmong populations in this country. While the Hmong communities in both cities are similar in size and have made significant political progress as evidenced by the election of Hmong candidates, the Hmong community in St. Paul has made greater inroads in the political realm. In addition to the elections of two Hmong candidates to the Minnesota State Legislature and two to the St. Paul School Board, the Hmong community in St. Paul has been able to engage local and state governments in Minnesotato address issues that affect the Hmong community. Through interviews, census data, and newspaper coverage of political campaigns, I show that Hmong in St. Paul have achieved greaterrepresentation in local and state governments and received greater support from government officials than Hmong in Fresno because Minnesota offers a social, economic, and politicalcontext that is favorable to fostering Hmong political involvement. Compared to Hmong in Fresno, Hmong in St. Paul have higher levels of socioeconomic resources and are more visible given their large size relative to other minority groups. They live in a region with consistently high levels of political participation and have political candidates who devote resources to mobilizing the Hmong community. Moreover, the Hmong vote has been critical to the success of Hmong candidates in St. Paul, an indication of the increasing political clout of the Hmong community there and a major reason why politicians in Minnesota are more willing to respond toissues that affect the Hmong community. Overall, this study highlights the importance of local and regional context in understanding the political incorporation of immigrants.

  20. A Study on the Views of Preschool Teachers and Teacher Candidates about the Concepts of Learning and Participation

    Science.gov (United States)

    Erkan, Semra; Akyol, Tugçe

    2017-01-01

    This study was conducted in order to examine the views of preschool teachers and teacher candidates about the concepts of learning and participation, and to explore how they perceive the relationship between the two. The study group comprised of 10 preschool teachers working at formal preschools located in Afyonkarahisar and affiliated with the…

  1. Obesity and treatment meanings in bariatric surgery candidates: a qualitative study.

    Science.gov (United States)

    da Silva, Susana Sofia Pereira; da Costa Maia, Angela

    2012-11-01

    This study used a qualitative approach to comprehend how the morbid obese conceptualize and deal with obesity and obesity treatment, with the particular aim of exploring the expectations and beliefs about the exigencies and the impact of bariatric surgery. The study population included 30 morbid obese patients (20 women and 10 men) with a mean age of 39.17 years (SD = 8.81) and a mean body mass index of 47.5 (SD = 8.2) (reviewer #2, comment #9) interviewed individually before surgery using open-ended questions. The interviews were audiotaped, transcribed, and then coded according to grounded analysis methodology. Three main thematic areas emerged from the data: obesity, eating behavior, and treatment. Obesity is described as a stable and hereditary trait. Although participants recognize that personal eating behavior exacerbates this condition, patients see their eating behavior as difficult to change and control. Food seems to be an ever-present dimension and a coping strategy, and to follow an adequate diet plan is described as a huge sacrifice. Bariatric surgery emerges as the only treatment for obesity, and participants highlight this moment as the beginning of a new life where health professionals have the main role. Bariatric surgery candidates see their eating behavior as out of their control, and to commit to its demands is seen as a big sacrifice. For these patients, surgery is understood as a miracle moment that will change their lives without requiring an active role or their participation. According to these results, it is necessary to validate them with qualitative and quantitative studies (reviewer #2, comment #3); it is necessary to promote a new awareness of the weight loss process and to empower patients before and after bariatric surgery.

  2. Inclusion and difusion studies of D in fusion breeding blanket candidate materials

    Energy Technology Data Exchange (ETDEWEB)

    Fan, L.

    2015-07-01

    Deuterium-Tritium (D-T) reaction is the most practical fusion reaction on the way to harness fusion energy. As tritium presents trace quantities on Earth [1], tritium fuel is essential to be generated simultaneously with the D-T reaction in a commerical fusion power plant. Tritium can be obtained in the lithium contained breeding blanket as a transmutation product of nuclear reaction 6Li (n, a)T. Li2T iO3 is considered to be one promising candidate solid tritium breeder material, due to its high lithium density, low activation, compatiblity with structure materials and high chemical stability. The tritium generated in Li2T iO3 breeding blanket needs to be collected and recycled back to the fusion reaction. Therefore, the study of the diffusion characteristic of breeder material Li2T iO3 is necessary to determine tritium mobility and tritium extraction efficiency. In order to study tritium release mechanism of Li2T iO3 breeding material in a fusion power plant environment, a fusion like neutron spectrum is essential while it is now not availble in any laboratory. One alternative is using ion accelerator or implantor to get energetic hydrogenic (H,D,T) ions impacting on breeding material, to simulate the tritium distribution situation. Because of the radioactive property of tritium which will complicate processing procedure, another isotope of hydrogen Deuterium is actually used to be studied. The defect structure in Li2T iO3, due to reactor exposure to fusion generated particles and ? ray irradiation, is achieved by energetic Ti ions. SRIM program is implemented to simulate the D ion or Ti ion distributions after bombarding, as well as the defects. X-ray diffraction technique helps to identify phase compositions. Transmission electron microscopy technique is used to observe the microstructures (Author)

  3. PPARγ Ligand as a Promising Candidate for Colorectal Cancer Chemoprevention: A Pilot Study

    Directory of Open Access Journals (Sweden)

    Hirokazu Takahashi

    2010-01-01

    Full Text Available Activating synthetic ligands for peroxisome proliferator-activated receptor gamma (PPARγ, such as pioglitazone, are commonly used to treat persons with diabetes mellitus with improvement of insulin resistance. Several reports have clearly demonstrated that PPARγ ligands could inhibit colorectal cancer cell growth and induce apoptosis. Meanwhile, aberrant crypt foci (ACF have come to be established as a biomarker of the risk of CRC in azoxymethane-treated mice and rats. In humans, ACF can be detected using magnifying colonoscopy. Previously, CRC and adenoma were used as a target for chemopreventive agents, but it needs a long time to evaluate, however, ACF can be a surrogate marker of CRC even for a brief period. In this clinical study, we investigated the chemopreventive effect of pioglitazone on the development of human ACF as a surrogate marker of CRC. Twenty-nine patients were divided into two groups, 20 were in the endoscopically normal control group and 9 were in the pioglitazone (15 mg/day group, and ACF and adenoma were examined before and after 1-month treatment. The number of ACF was significantly decreased (5.8±1.1 to 3.3±2.3 after 1 month of pioglitazone treatment, however, there was no significant change in the number of crypts/ACF or in the number and size of adenomas. Pioglitazone may have a clinical application as a cancer-preventive drug. This investigation is just a pilot study, therefore, further clinical studies are needed to show that the PPARγ ligand may be a promising candidate as a chemopreventive agent for colorectal carcinogenesis.

  4. PROTECTIVE ACTIVITY STUDY OF A CANDIDATE VACCINE AGAINST ROTAVIRUS INFECTION BASED ON RECOMBINANT PROTEIN FliCVP6VP8

    Directory of Open Access Journals (Sweden)

    I. V. Dukhovlinov

    2016-01-01

    Full Text Available Rotavirus infection is among leading causes of severe diarrhea which often leads to severe dehydration, especially, in children under 5 years old. In Russia, the incidence of rotavirus infection is constantly increased, due to higher rates of actual rotavirus infection cases and improved diagnostics of the disease. Immunity to rotavirus is unstable, thus causing repeated infections intra vitam. Anti-infectious resistance in reconvalescents is explained by induction of specific IgM, IgG, and, notably, IgA antibodies. Due to absence of market drugs with direct action against rotavirus, a rational vaccination is considered the most effective way to control the disease. Currently available vaccines for prevention of rotavirus infection are based on live attenuated rotavirus strains, human and/or animal origin, which replicate in human gut. Their implementation may result into different complications. Meanwhile, usage of vaccines based on recombinant proteins is aimed to avoid risks associated with introduction of a complete virus into humans. In this paper, we studied protective activity of candidate vaccines against rotavirus.In this work we studied protective activity of a candidate vaccine against rotavirus infection based on recombinant FliCVP6VP8 protein which includes VP6 and VP8, as well as components of Salmonella typhimurium flagellin (FliC as an adjuvant. Different components are joined by flexible bridges. Efficiency of the candidate vaccine was studied in animal model using Balb/c mice. We have shown high level of protection which occurs when the candidate vaccine is administered twice intramuscularly. Complete protection of animals against mouse rotavirus EDC after intramuscular immunization with a candidate vaccine was associated with arising rotavirus-specific IgA and IgG antibodies in serum and intestine of immunized animals. The efficacy of candidate vaccine based on recombinant protein FliCVP6VP8 against rotavirus infection was

  5. Politics without Politics

    OpenAIRE

    Dean, Jodi

    2009-01-01

    textabstractProf.dr. Jodi Dean, hoogleraar politieke filosofie aan Hobart and William Smith Colleges (Geneva, New York), sprak donderdag 19 februari 2009 haar inaugurele rede uit, getiteld "Politics without politics". Dean is dit jaar Erasmus Professor op de Erasmus Chair of Humanities in de Faculteit der Wijsbegeerte. De Erasmus Wisselleerstoel is ingesteld door de G. Ph. Verhagen Stichting. V In haar oratie gaat Dean in op het thema democratie in relatie tot linkse politiek. Enkele politiek...

  6. The Memory of Katyn in Polish Political Discourse: A Quantitative Study

    OpenAIRE

    Fredheim, Rolf

    2014-01-01

    This study uses quantitative methods to explore how the memory of Katyn is mobilised in political discourse. The scholarly literature on memory conflict tends to see international memory disputes as an expression of a state's interests as a whole; this study analyses when hostile rhetoric is mobilised and finds that in Poland Katyn is invoked as part of an opposition strategy that criticises the incumbent regime for undermining the national interest. Periods of accelerated debate about the si...

  7. The presidential politics of climate discourse: energy frames, policy, and political tactics from the 2016 Primaries in the United States

    OpenAIRE

    Brown, George; Sovacool, Benjamin K

    2017-01-01

    his study presents the results of an investigation into the frequency in which four candidates of the 2016 United States Presidential Primary season communicated their political positions on climate change, and how they subsequently framed these stances in numerous contextual drivers alongside energy policies. A systematic content analysis of political debates, campaign speeches, and press statements reveals how Hillary Clinton, Bernie Sanders, Donald Trump, and Ted Cruz undertook in vote-see...

  8. Functional complementation studies identify candidate genes and common genetic variants associated with ovarian cancer survival

    DEFF Research Database (Denmark)

    Quaye, Lydia; Dafou, Dimitra; Ramus, Susan J

    2009-01-01

    Common germline genetic variation and/or somatic alterations in tumours may be associated with survival in women diagnosed with ovarian cancer. The successful identification of genetic associations relies on a suitable strategy for identifying and testing candidate genes. We used microcell-mediat...

  9. The Evolution of Foreign Language AP Exam Candidates: A 36-Year Descriptive Study

    Science.gov (United States)

    Brown, Alan V.; Thompson, Gregory L.

    2016-01-01

    Using a data set exclusively prepared for and licensed to them by the College Board, the authors examined the growth of the Advanced Placement program in foreign languages and overall trends in regard to the number of candidates who sat for the foreign language exams, their gender, their scores, and their ethnicity over the 36-year period covering…

  10. Risk prediction models for selection of lung cancer screening candidates: A retrospective validation study

    NARCIS (Netherlands)

    K. ten Haaf (Kevin); J. Jeon (Jihyoun); M.C. Tammemagi (Martin); S.S. Han (Summer); C.Y. Kong (Chung Yin); S.K. Plevritis (Sylvia); E. Feuer (Eric); H.J. de Koning (Harry); E.W. Steyerberg (Ewout W.); R. Meza (Rafael)

    2017-01-01

    textabstractBackground: Selection of candidates for lung cancer screening based on individual risk has been proposed as an alternative to criteria based on age and cumulative smoking exposure (pack-years). Nine previously established risk models were assessed for their ability to identify those most

  11. A Study of Teacher Candidates' Experiences Investigating Global Climate Change within an Elementary Science Methods Course

    Science.gov (United States)

    Hestness, Emily; McGinnis, J. Randy; Riedinger, Kelly; Marbach-Ad, Gili

    2011-01-01

    We investigated the inclusion of a curricular module on global climate change in an Elementary Science Methods course. Using complementary research methods, we analyzed findings from 63 teacher candidates' drawings, questionnaires, and journal entries collected throughout their participation in the module. We highlighted three focal cases to…

  12. Potentiodynamic polarization studies on candidate container alloys for the Tuff Repository

    International Nuclear Information System (INIS)

    Thompson, N.G.; Beavers, J.A.; Durr, C.L.

    1992-01-01

    Cortest Columbus Technologies, Inc. (CC Technologies) is investigating the long-term performance of container materials used for high-level radioactive waste packages. This information is being developed for the Nuclear Regulatory Commission to aid in their assessment of the Department of Energy's application to construct a geologic repository for disposal of high-level radioactive waste. This report summarizes the results of cyclic-potentiodynamic-polarization (CCP) studies performed on candidate container materials for the Tuff Repository. The CPP technique was used to provide an understanding of how specific variables such as environmental composition, temperature, alloy composition, and welding affect both the general- and localized-corrosion behavior of two copper-base and two Fe-Cr-Ni alloys in simulated repository environments. A statistically-designed test solution matrix was formulated, based on an extensive search of the literature, to evaluate the possible range of environmental species that may occur in the repository over the life of the canister. Forty-two CPP curves were performed with each alloy and the results indicated that several different types of corrosion were possible. The copper-base alloys exhibited unusual CCP behavior in that hysteresis was not always associated with pitting. The effects of temperature on the corrosions behavior were evaluated in two types of tests; isothermal tests at temperatures from 50 degrees C to 90 degrees C and heat-transfer tests where the solution was maintained at 50 degrees C and the specimen was internally heated to 90 degrees C. In the isothermal test, CPP curves were obtained with each alloy in simulated environments at 50 degrees C, 75 degrees C, and 90 degrees C. The results of these CCP experiments indicated that no systematic trends were evident for the environments tested. Lastly, the effects of welding on the corrosion behavior of the alloys in simulated environments were examined

  13. Anti-HIV-1 activity of anionic polymers: a comparative study of candidate microbicides

    Directory of Open Access Journals (Sweden)

    Li Yun-Yao

    2002-11-01

    Full Text Available Abstract Background Cellulose acetate phthalate (CAP in soluble form blocks coreceptor binding sites on the virus envelope glycoprotein gp120 and elicits gp41 six-helix bundle formation, processes involved in virus inactivation. CAP is not soluble at pH Methods Enzyme linked immunosorbent assays (ELISA were used to (1 study HIV-1 IIIB and BaL binding to micronized CAP; (2 detect virus disintegration; and (3 measure gp41 six-helix bundle formation. Cells containing integrated HIV-1 LTR linked to the β-gal gene and expressing CD4 and coreceptors CXCR4 or CCR5 were used to measure virus infectivity. Results 1 HIV-1 IIIB and BaL, respectively, effectively bound to micronized CAP. 2 The interaction between HIV-1 and micronized CAP led to: (a gp41 six-helix bundle formation; (b virus disintegration and shedding of envelope glycoproteins; and (c rapid loss of infectivity. Polymers other than CAP, except Carbomer 974P, elicited gp41 six-helix bundle formation in HIV-1 IIIB but only poly(napthalene sulfonate, in addition to CAP, had this effect on HIV-1 BaL. These polymers differed with respect to their virucidal activities, the differences being more pronounced for HIV-1 BaL. Conclusions Micronized CAP is the only candidate topical microbicide with the capacity to remove rapidly by adsorption from physiological fluids HIV-1 of both the X4 and R5 biotypes and is likely to prevent virus contact with target cells. The interaction between micronized CAP and HIV-1 leads to rapid virus inactivation. Among other anionic polymers, cellulose sulfate, BufferGel and aryl sulfonates appear most effective in this respect.

  14. Text Messaging to Reduce Alcohol Relapse in Prelisting Liver Transplant Candidates: A Pilot Feasibility Study.

    Science.gov (United States)

    DeMartini, Kelly S; Schilsky, Michael L; Palmer, Amanda; Fehon, Dwain C; Zimbrean, Paula; O'Malley, Stephanie S; Lee, Hochang B; Toll, Benjamin A

    2018-03-02

    Many liver transplantation programs require documented alcohol sobriety prior to United Network for Organ Sharing (UNOS) listing. This pilot study examined the feasibility of the first mobile, alcohol relapse prevention intervention for liver transplant patients with alcoholic liver disease (ALD). This was a randomized 8-week pilot feasibility trial of a text message-based alcohol intervention. In-treatment assessment was conducted at 4 weeks (4W), and immediate posttreatment assessment was conducted at 8W. Participants were liver transplant candidates (N = 15) diagnosed with ALD who reported at least 1 drinking episode in the past year. Primary feasibility outcomes were percent of messages responded to and posttreatment intervention satisfaction ratings. Preliminary clinical efficacy outcomes were any biologically confirmed alcohol consumption, stress, abstinence self-efficacy, and alcohol craving. On feasibility outcomes, participants responded to 81% of messages received and reported high rates of intervention satisfaction, looked forward to receiving the messages, and found it easy to complete the intervention. On preliminary efficacy outcomes, zero participants in the text message (TM) had positive urine alcohol tests at 8W. Two of the 6 participants in standard care (SC) tested positive at 8W. No effects were seen on craving. For stress, a condition × time interaction emerged. TM participants had less stress at 4W and 8W compared with SC at baseline. They maintained their stress level during the intervention. For self-efficacy, a trend for condition effect emerged. TM participants had higher self-efficacy than SC participants. Participants reported high satisfaction with the intervention, looked forward to the messages, and found it easy to complete. Participants who received the intervention had better treatment outcomes than those who received standard care. They maintained higher levels of self-efficacy and lower stress. Mobile alcohol interventions

  15. A candidate gene-based association study of tocopherol content and composition in rapeseed (Brassica napus

    Directory of Open Access Journals (Sweden)

    Steffi eFritsche

    2012-06-01

    Full Text Available Rapeseed (Brassica napus L. is the most important oil crop of temperate climates. Rapeseed oil contains tocopherols, also known as vitamin E, which is an indispensable nutrient for humans and animals due to its antioxidant and radical scavenging abilities. Moreover, tocopherols are also important for the oxidative stability of vegetable oils. Therefore, seed oil with increased tocopherol content or altered tocopherol composition is a target for breeding. We investigated the role of nucleotide variations within candidate genes from the tocopherol biosynthesis pathway. Field trials were carried out with 229 accessions from a worldwide B. napus collection which was divided into two panels of 96 and 133 accessions. Seed tocopherol content and composition were measured by HPLC. High heritabilities were found for both traits, ranging from 0.62 to 0.94. We identified polymorphisms by sequencing selected regions of the tocopherol genes from the 96 accession panel. Subsequently, we determined the population structure (Q and relative kinship (K as detected by genotyping with genome-wide distributed SSR markers. Association studies were performed using two models, the structure-based GLM+Q and the PK mixed model. Between 26 and 12 polymorphisms within two genes (BnaX.VTE3.a, BnaA.PDS1.c were significantly associated with tocopherol traits. The SNPs explained up to 16.93 % of the genetic variance for tocopherol composition and up to 10.48 % for total tocopherol content. Based on the sequence information we designed CAPS markers for genotyping the 133 accessions from the 2nd panel. Significant associations with various tocopherol traits confirmed the results from the first experiment. We demonstrate that the polymorphisms within the tocopherol genes clearly impact tocopherol content and composition in B. napus seeds. We suggest that these nucleotide variations may be used as selectable markers for breeding rapeseed with enhanced tocopherol quality.

  16. A candidate-gene association study for berry colour and anthocyanin content in Vitis vinifera L.

    Directory of Open Access Journals (Sweden)

    Silvana Cardoso

    Full Text Available Anthocyanin content is a trait of major interest in Vitis vinifera L. These compounds affect grape and wine quality, and have beneficial effects on human health. A candidate-gene approach was used to identify genetic variants associated with anthocyanin content in grape berries. A total of 445 polymorphisms were identified in 5 genes encoding transcription factors and 10 genes involved in either the biosynthetic pathway or transport of anthocyanins. A total of 124 SNPs were selected to examine association with a wide range of phenotypes based on RP-HPLC analysis and visual characterization. The phenotypes were total skin anthocyanin (TSA concentration but also specific types of anthocyanins and relative abundance. The visual assessment was based on OIV (Organisation Internationale de la Vigne et du Vin descriptors for berry and skin colour. The genes encoding the transcription factors MYB11, MYBCC and MYC(B were significantly associated with TSA concentration. UFGT and MRP were associated with several different types of anthocyanins. Skin and pulp colour were associated with nine genes (MYB11, MYBCC, MYC(B, UFGT, MRP, DFR, LDOX, CHI and GST. Pulp colour was associated with a similar group of 11 genes (MYB11, MYBCC, MYC(B, MYC(A, UFGT, MRP, GST, DFR, LDOX, CHI and CHS(A. Statistical interactions were observed between SNPs within the transcription factors MYB11, MYBCC and MYC(B. SNPs within LDOX interacted with MYB11 and MYC(B, while SNPs within CHI interacted with MYB11 only. Together, these findings suggest the involvement of these genes in anthocyanin content and on the regulation of anthocyanin biosynthesis. This work forms a benchmark for replication and functional studies.

  17. Warfarin Anticoagulation Therapy in Caribbean Hispanics of Puerto Rico: A Candidate Gene Association Study

    Directory of Open Access Journals (Sweden)

    Karla Claudio-Campos

    2017-06-01

    Full Text Available Existing algorithms account for ~50% of observed variance in warfarin dose requirements after including common polymorphisms. However, they do not perform as well in populations other than Caucasians, in part because some ethno-specific genetic variants are overlooked. The objective of the present study was to identify genetic polymorphisms that can explain variability in warfarin dose requirements among Caribbean Hispanics of Puerto Rico. Next-Generation Sequencing of candidate genes CYP2C9 and VKORC1 and genotyping by DMET® Plus Assay of cardiovascular patients were performed. We also aimed at characterizing the genomic structure and admixture pattern of this study cohort. Our study used the Extreme Discordant Phenotype approach to perform a case-control association analysis. The CYP2C9 variant rs2860905, which was found in all the major haplotypes occurring in the Puerto Rican population, showed stronger association with warfarin sensitivity (<4 mg/day than common variants CYP2C9*2 and CYP2C9*3. Although, CYP2C9*2 and CYP2C9*3 are separately contained within two of the haplotypes, 10 subjects with the sensitive phenotype were carriers of only the CYP2C9 rs2860905 variant. Other polymorphisms in CES2 and ABCB1 were found to be associated with warfarin resistance. Incorporation of rs2860905 in a regression model (R2 = 0.63, MSE = 0.37 that also includes additional genetics (i.e., VKORC1-1639 G>A; CYP2C9 rs1856908; ABCB1 c.IVS9-44A>G/ rs10276036; CES2 c.269-965A>G/ rs4783745 and non-genetic factors (i.e., hypertension, diabetes and age showed better prediction of warfarin dose requirements than CYP2C9*2 and CYP2C9*3 combined (partial R2 = 0.132 vs. 0.023 and 0.007, respectively, p < 0.001. The genetic background of Puerto Ricans in the study cohort showed a tri-hybrid admixture pattern, with a slightly higher than expected contribution of Native American ancestry (25%. The genomic diversity of Puerto Ricans is highlighted by the presence of

  18. Thermal Stability Studies of Candidate Decontamination Agents for Hanford’s Plutonium Finishing Plant Plutonium-Contaminated Gloveboxes

    Energy Technology Data Exchange (ETDEWEB)

    Scheele, Randall D.; Cooper, Thurman D.; Jones, Susan A.; Ewalt, John R.; Compton, James A.; Trent, Donald S.; Edwards, Matthew K.; Kozelisky, Anne E.; Scott, Paul A.; Minette, Michael J.

    2005-09-29

    This report provides the results of PNNL's and Fluor's studies of the thermal stabilities of potential wastes arising from decontamination of Hanford's Plutonium Finishing Plant's plutonium contaminated gloveboxes. The candidate wastes arising from the decontamination technologies ceric nitrate/nitric acid, RadPro, Glygel, and Aspigel.

  19. Campaigning on the Internet: 2008 Presidential General Election Candidate Webpage

    Directory of Open Access Journals (Sweden)

    William L. Benoit

    2016-12-01

    Full Text Available The Internet is becoming an increasingly important component of political campaigns. This study employed content analysis to apply Functional Theory and Issue Ownership Theory to Obama’s and McCain’s presidential candidate webpages in the 2008 campaign. Acclaims (92% were more common than attacks (98%; defenses did not occur in this sample. Policy (82% was addressed more than character (18%. When discussing policy, these candidates addressed future plans most frequently, followed by general goals and then past deeds; on character, candidates discussed ideals, then personal qualities, and then leadership ability. This study shows that as candidates use the Internet to reach voters, their webpages conform to theoretical expectations.

  20. Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease.

    Science.gov (United States)

    Li, Hao; Wetten, Sally; Li, Li; St Jean, Pamela L; Upmanyu, Ruchi; Surh, Linda; Hosford, David; Barnes, Michael R; Briley, James David; Borrie, Michael; Coletta, Natalie; Delisle, Richard; Dhalla, Daniella; Ehm, Margaret G; Feldman, Howard H; Fornazzari, Luis; Gauthier, Serge; Goodgame, Neil; Guzman, Danilo; Hammond, Sandra; Hollingworth, Paul; Hsiung, Ging-Yuek; Johnson, Joan; Kelly, Devon D; Keren, Ron; Kertesz, Andrew; King, Karen S; Lovestone, Simon; Loy-English, Inge; Matthews, Paul M; Owen, Michael J; Plumpton, Mary; Pryse-Phillips, William; Prinjha, Rab K; Richardson, Jill C; Saunders, Ann; Slater, Andrew J; St George-Hyslop, Peter H; Stinnett, Sandra W; Swartz, Jina E; Taylor, Rachel L; Wherrett, John; Williams, Julie; Yarnall, David P; Gibson, Rachel A; Irizarry, Michael C; Middleton, Lefkos T; Roses, Allen D

    2008-01-01

    . This could be a consequence of the coevolution of more than 1 susceptibility allele, such as APOC1, in this region. We also provide new evidence for additional candidate genetic risk factors for AD that can be tested in further studies.

  1. Emotion and Memory Responses for Negative Political Advertising: A Study of Television Commercials Used in the 1988 Presidential Election.

    Science.gov (United States)

    Newhagen, John E.; Reeves, Byron

    A study tested the relationships between emotion in political television commercials, viewer memory, and evaluations of those advertisements. Subjects were in two groups, one of 31 undergraduates and one of 30 adults from the local community. Subjects in the first group were shown 34 different political ads followed by 28 30-second advertisements.…

  2. Political Terrorism: A Mini-Course for High School Social Studies.

    Science.gov (United States)

    Ellington, Lucien

    By participating in the 2-week mini-course, high school students will learn that (1) there is a difference between political terror and other criminal activity; (2) governments as well as nongovernmental groups engage in political terrorism; (3) political terrorism has been present throughout history; (4) political terrorism is a world wide…

  3. Politics of Deceit and Reality in Africa: A Study of Joseph Edoki's ...

    African Journals Online (AJOL)

    Politics and political activities have been very important issues that most critics and literary writers have devoted their attention in Africa. Political matter is a very prominent topic of contemporary scholarship. This is due to the fact that African literary works, being reflections of the debased and unholy political activities of the ...

  4. A multi-level geographical study of Italian political elections from Twitter data.

    Science.gov (United States)

    Caldarelli, Guido; Chessa, Alessandro; Pammolli, Fabio; Pompa, Gabriele; Puliga, Michelangelo; Riccaboni, Massimo; Riotta, Gianni

    2014-01-01

    In this paper we present an analysis of the behavior of Italian Twitter users during national political elections. We monitor the volumes of the tweets related to the leaders of the various political parties and we compare them to the elections results. Furthermore, we study the topics that are associated with the co-occurrence of two politicians in the same tweet. We cannot conclude, from a simple statistical analysis of tweet volume and their time evolution, that it is possible to precisely predict the election outcome (or at least not in our case of study that was characterized by a "too-close-to-call" scenario). On the other hand, we found that the volume of tweets and their change in time provide a very good proxy of the final results. We present this analysis both at a national level and at smaller levels, ranging from the regions composing the country to macro-areas (North, Center, South).

  5. Phase I Randomized Safety Study of Twice Daily Dosing of Acidform Vaginal Gel: Candidate Antimicrobial Contraceptive

    Science.gov (United States)

    Keller, Marla J.; Carpenter, Colleen A.; Lo, Yungtai; Einstein, Mark H.; Liu, Congzhou; Fredricks, David N.; Herold, Betsy C.

    2012-01-01

    of antimicrobial (lactoferrin) and anti-inflammatory (IL-1ra) proteins. These findings indicate the need for additional safety studies of this candidate non-hormonal contraceptive. Trial Registration ClinicalTrials.gov NCT00850837 PMID:23056520

  6. Women, Politics, Elections, and Citizenship.

    Science.gov (United States)

    Webster, Gerald R.

    2000-01-01

    Outlines the historical development of women's legal and political status in the United States, focusing on suffrage, the three "waves" of women's movements, and access to elected office. Discusses three impediments of electing women candidates to public office: (1) solidarity; (2) political culture; and (3) the impact of the single-member…

  7. Gaps in Political Interest

    DEFF Research Database (Denmark)

    Robison, Joshua

    2015-01-01

    Political interest fundamentally influences political behavior, knowledge, and persuasion (Brady, Verba, & Schlozman, 1995; Delli Carpini & Keeter, 1996; Luskin, 1990; Zukin, Andolina, Keeter, Jenkins, & Delli Carpini, 2006). Since the early 1960s, the American National Election Studies (ANES) ha...

  8. An appraisal of the utilisation of social media for political ...

    African Journals Online (AJOL)

    The study is a survey aimed at examining the utilisation of social media for political communication during the 2011 presidential election in Nigeria. The rationale behind the study was to determine whether voters' choice of presidential candidates was influenced by their social media use. 249 respondents selected through ...

  9. Characterization nanoparticles-based vaccines and vaccine candidates: a Transmission Electron Microscopy study

    Directory of Open Access Journals (Sweden)

    I. Menéndez I

    2016-05-01

    Full Text Available Transmission Electron Microscopy (TEM is a valuable tool for the biotech industry. This paper summarizes some of the contributions of MET in the characterization of the recombinant antigens are part of vaccines or vaccine candidates obtained in the CIGB. It mentions the use of complementary techniques MET (Negative staining, and immunoelectron that enhance visualization and ultrastructural characterization of the recombinant proteins obtained by Genetic Engineering.

  10. Selection in the dopamine receptor 2 gene: a candidate SNP study

    Directory of Open Access Journals (Sweden)

    Tobias Göllner

    2015-08-01

    Full Text Available Dopamine is a major neurotransmitter in the human brain and is associated with various diseases. Schizophrenia, for example, is treated by blocking the dopamine receptors type 2. Shaner, Miller & Mintz (2004 stated that schizophrenia was the low fitness variant of a highly variable mental trait. We therefore explore whether the dopamine receptor 2 gene (DRD2 underwent any selection processes. We acquired genotype data of the 1,000 Genomes project (phase I, which contains 1,093 individuals from 14 populations. We included single nucleotide polymorphisms (SNPs with two minor allele frequencies (MAFs in the analysis: MAF over 0.05 and over 0.01. This is equivalent to 151 SNPs (MAF > 0.05 and 246 SNPs (MAF > 0.01 for DRD2. We used two different approaches (an outlier approach and a Bayesian approach to detect loci under selection. The combined results of both approaches yielded nine (MAF > 0.05 and two candidate SNPs (MAF > 0.01, under balancing selection. We also found weak signs for directional selection on DRD2, but in our opinion these were too weak to draw any final conclusions on directional selection in DRD2. All candidates for balancing selection are in the intronic region of the gene and only one (rs12574471 has been mentioned in the literature. Two of our candidate SNPs are located in specific regions of the gene: rs80215768 lies within a promoter flanking region and rs74751335 lies within a transcription factor binding site. We strongly encourage research on our candidate SNPs and their possible effects.

  11. Trends in Addressing Social Needs: A Longitudinal Study of Congregation-Based Service Provision and Political Participation

    Directory of Open Access Journals (Sweden)

    Brad R. Fulton

    2016-05-01

    Full Text Available When congregations seek to address social needs, they often pursue this goal through acts of service and political engagement. Over the past three decades, a tremendous amount of research has been dedicated to analyzing congregation-based service provision and political participation. However, little is known about how congregations’ involvement in these arenas has changed during this period. To help fill this gap, this study analyzes three waves of data from a national survey of congregations to assess how congregations’ participation patterns in service-related and political activities have been changing since the 1990s. It also examines trends among subpopulations of congregations grouped by their religious tradition, ethnoracial composition, and ideological orientation. Overall, this study finds that among most types of congregations, the percentage participating in service-related activities is substantial and increasing, while the percentage participating in political activities is less substantial and decreasing. This decline in political participation has implications for the role congregations play in addressing social needs. Relieving immediate needs through service provision without also pursuing long-term solutions through political participation can limit congregations’ ability to comprehensively address social needs. Among the few types of congregations that have high and/or increasing participation rates in both service-related and political activities are Catholic, predominantly Hispanic, and politically liberal congregations.

  12. A comparative study of oral candidal species carriage in patients with type1 and type2 diabetes mellitus

    Science.gov (United States)

    Shenoy, Mangesh P; Puranik, Rudrayya S; Vanaki, Shrinivas S; Puranik, Surekha R; Shetty, Pushparaja; Shenoy, Radhika

    2014-01-01

    Context: Diabetes mellitus can have profound effects upon the oral tissues especially in patients with poor glycemic control being prone to severe and/or recurrent infections particularly candidiasis. The main aim was to study the association between Type 1 and Type 2 diabetes mellitus and candidal carriage. Materials and Methods: The study design comprised of previously diagnosed 30 patients each with type 1 diabetes mellitus (Group A) and type 2 diabetes mellitus (Group B) and 30 age-, sex- and dental status-matched healthy non-diabetic individuals as controls (Group C). The saliva samples were collected and inoculated onto Sabouraud dextrose agar (SDA) and chromogenic agar culture medium. Candidal colony forming units per ml (CFU/ml) values were determined. Statistical Analysis: Data were analyzed by χ2 test, Mann-Whitney U-test, Spearman's rank correlation and Karl Pearson's correlation coefficient. Results: Data analysis showed statistically significant higher positive candidal growth in Group A and Group B when compared to Group C. The CFU/ml values were significantly higher in Groups A and B as compared with Group C. Significant positive correlation of CFU/ml with fasting blood sugar level and HbA1c% in both Groups A and B was seen. Oral signs and symptoms observed in diabetics were dry mouth, burning sensation, fissuring and atrophic changes of tongue and erythematous areas, which positively correlated with candidal load. Conclusion: The glycemic control status of the diabetic patients may directly influence candidal colonization. The quantitative and biochemical characterization allows better insight into the study of association of diabetes mellitus and candida. PMID:25364182

  13. Classification study of WISE infrared sources: identification of candidate asymptotic giant branch stars

    Science.gov (United States)

    Tu, Xun; Wang, Zhong-Xiang

    2013-03-01

    In the Wide-field Infrared Survey Explorer (WISE) all-sky source catalog there are 76 million mid-infrared point sources that were detected in the first three WISE bands and have association with only one 2MASS near-IR source within 3″. We search for their identifications in the SIMBAD database and find 3.2 million identified sources. Based on these known sources, we establish three criteria for selecting candidate asymptotic giant branch (AGB) stars in the Galaxy, which are three defined zones in a color-color diagram, Galactic latitude |b| W3c W3c, we estimate their distances and derive their Galactic distributions. The candidates are generally distributed around the Galactic center uniformly, with 68% (1-σ) of them within approximately 8 kpc. We discuss the idea that optical spectroscopy can be used to verify the C-rich AGB stars in our candidates, and thus a fraction of them (~10%) will be good targets for the Large Sky Area Multi-Object Fiber Spectroscopic Telescope (LAMOST) survey that is planned to start in fall of 2012.

  14. Virtually Impossible: Deleuze and Derrida on the Political Problem of Islands (and Island Studies

    Directory of Open Access Journals (Sweden)

    Stewart Williams

    2012-11-01

    Full Text Available It is commonplace to think of an island as a discreetly bounded unit. Selected writings on islands by the poststructuralist philosophers Gilles Deleuze and Jacques Derrida reveal the island variously to be both real and imaginary, mythological and scientific, but as most problematic when constituted in political terms as an indivisible, sovereign entity. These two thinkers’ more broadly developed concepts of the virtual and the impossible, respectively, are seen to disrupt any assumptions about the fixity and closure of the island polity. Instead they emphasize its actualization through processual relations that can be difficult yet dynamic and decisive in effecting the move from being to becoming-other. As the possibilities for instituting more ethical as well as different political relations open up, the question of island studies remaining in its currently coherent, familiar form is raised for consideration.

  15. Linkage study of nonsyndromic cleft lip with or without cleft palate using candidate genes and mapped polymorphic markers

    Energy Technology Data Exchange (ETDEWEB)

    Stein, J.D.; Nelson, L.D.; Conner, B.J. [Univ. of Texas, Houston (United States)] [and others

    1994-09-01

    Nonsyndromic cleft lip with or without cleft palate (CL(P)) involves fusion or growth failure of facial primordia during development. Complex segregation analysis of clefting populations suggest that an autosomal dominant gene may play a role in this common craniofacial disorder. We have ascertained 16 multigenerational families with CL(P) and tested linkage to 29 candidate genes and 139 mapped short tandem repeat markers. The candidate genes were selected based on their expression in craniofacial development or were identified through murine models. These include: TGF{alpha}, TGF{beta}1, TGF{beta}2, TGF{beta}3, EGF, EGFR, GRAS, cMyc, FGFR, Jun, JunB, PDFG{alpha}, PDGF{beta}, IGF2R, GCR Hox7, Hox8, Hox2B, twirler, 5 collagen and 3 extracellular matrix genes. Linkage was tested assuming an autosomal dominant model with sex-specific decreased penetrance. Linkage to all of the candidate loci was excluded in 11 families. RARA was tested and was not informative. However, haplotype analysis of markers flanking RARA on 17q allowed exclusion of this candidate locus. We have previously excluded linkage to 61 STR markers in 11 families. Seventy-eight mapped short tandem repeat markers have recently been tested in 16 families and 30 have been excluded. The remaining are being analyzed and an exclusion map is being developed based on the entire study results.

  16. Michael Young, the Institute of Community Studies, and the Politics of Kinship.

    Science.gov (United States)

    Butler, Lise

    2015-01-01

    This article examines the East London-based Institute of Community Studies, and its founder, Michael Young, to show that sociology and social research offered avenues for left-wing political expression in the 1950s. Young, who had previously been Head of the Labour Party Research Department during the Attlee government, drew upon existing currents of psychological and sociological research to emphasize the continuing relevance of the extended family in industrial society and to offer a model of socialist citizenship, solidarity and mutual support not tied to productive work. Young and his colleagues at the Institute of Community Studies promoted the supportive kinship networks of the urban working class, and an idealized conception of the relationships between women, to suggest that family had been overlooked by the left and should be reclaimed as a progressive force. The article shows that the Institute's sociological work was informed by a pre-existing concern with family as a model for cooperative socialism, and suggests that sociology and social research should be seen as important sources of political commentary for scholars of post-war politics.

  17. Media competition and electoral politics

    NARCIS (Netherlands)

    Piolatto, A.; Schütt, F.

    2015-01-01

    We build a framework linking competition in the media market to political participation. Media outlets report on the ability of candidates running for office and compete for audience through their choice of slant. Citizens consume news only if the expected utility of being informed about candidates'

  18. Political Marketing Success: An Investigation on 2015 Iranian Parliamentary Elections

    Directory of Open Access Journals (Sweden)

    Seyed Mohsen Lotfi Ashtiani

    2017-02-01

    Full Text Available This study investigates factors affecting the success of political marketing by basing on a fieldwork. To evaluate proposed hypotheses, a questionnaire was used to collect data. This research’s statistical society includes citizens of Arak city by using proportional sampling method and reaches 287 completed questionnaires. According to the data analysis, the results indicate that the market–oriented strategy adoption, doing of effective research about voters, voters division, candidates status and creation and management of mental image have the positive effect on the political marketing. Given the importance of political marketing and proper use of the marketing techniques in the campaigns and realizations of successful political marketing, this study introduces advantages of political marketing and explains how to use it and provides a conceptual model.

  19. Basic Teaching Skill Quality of Teacher Candidates in Microteaching Study Subject of Department of Biology Education, Pasir Pengaraian University

    OpenAIRE

    Nurul Afifah

    2017-01-01

    This research purposed on knowing basic teaching skill quality of teacher candidates in study subject Microteaching of Department of Biology Education, Pasir Pengaraian University, academic year 2016/2016. This research is qualitative research. This research has been done in February to June 2015. The subject of this research is all of the 6th semester students who are taking the Microteaching Study Subject. The instruments of this research including syllabus, teaching plans, and questionnair...

  20. A Conceptual Shift in Studies of Belonging and the Politics of Belonging

    Directory of Open Access Journals (Sweden)

    Eva Youkhana

    2015-07-01

    Full Text Available The study of belonging, its underlying notions, and the politics of belonging shows that social, political, and territorial demarcations are still based on essentialist conceptions of the collective. These are often applied and reproduced in the social sciences as a result of methodological nationalism. Space-sensitive studies of migration and globalization and a return to the material have recently challenged social constructivist lines of argumentation and have provoked a conceptual shift from analytical categories with inherent spatiality, territoriality, and boundary marking to concepts based on movement and flow. In this paper the analysis of belonging and the related politics of belonging in migration studies incorporates space as an analytical category that cross-cuts established categorizations such as race, class, gender, and stage in the life cycle, and integrates a material semiotic perspective more systematically into the study of social relations at the intersection of the social categories mentioned. A new concept of belonging is defined which reflects the complex relations that individuals have with other people, circulating objects, artefacts, and changing social, political, and cultural landscapes, thus mirroring both the material conditions and the underlying power relations. Such an understanding of belonging proceeds from social naturalizations and fixations to the multiplicity and situatedness of individual attachments, which entangle social, imagined, and sensual-material relations that are constantly re-articulated and re-negotiated by actors in their day-to-day practices. In such a reading, belonging comes into being as a result of individual life stories, versatile contexts, and situated experiences and acts. In times of constant exchange through travel, mass media, and communication technologies, the conceptualization of belonging questions established sociocultural and political demarcations, indicates the

  1. The genetic and environmental foundations of political, psychological, social, and economic behaviors: a panel study of twins and families.

    Science.gov (United States)

    Hatemi, Peter K; Smith, Kevin; Alford, John R; Martin, Nicholas G; Hibbing, John R

    2015-06-01

    Here we introduce the Genetic and Environmental Foundations of Political and Economic Behaviors: A Panel Study of Twins and Families (PIs Alford, Hatemi, Hibbing, Martin, and Smith). This study was designed to explore the genetic and environmental influences on social, economic, and political behaviors and attitudes. It involves identifying the psychological mechanisms that operate on these traits, the heritability of complex economic and political traits under varying conditions, and specific genetic correlates of attitudes and behaviors. In addition to describing the study, we conduct novel analyses on the data, estimating the heritability of two traits so far unexplored in the extant literature: Machiavellianism and Baron-Cohen's Empathizing Quotient.

  2. A Study on Freedom of Speech Based on Politness Strategies Used by the Jakarta Post Readers

    Directory of Open Access Journals (Sweden)

    Muhartoyo Muhartoyo

    2011-10-01

    Full Text Available Freedom of speech or expression is an indication of a democratic country. Indonesia that has transformed itself from an authoritarian government during the New Order Era into a democratic country in the so called Reform Era. This study is an attempt to find out the existence of freedom of expression in the Indonesian printed media. The data were collected from the Jakarta Post Readers’Forum from 1 November 2010 to 28 February 2011. The data were then classified and analysed based on Brown and Levinson’s theory of politeness strategies. The data analysis shows that a lot of utterances can be classified under Politeness Strategy 1 (the least polite strategy out of the four strategies. This proves that people are now free to express their ideas and criticisms in the most direct manner without fear of being arrested or reprimanded by the government. Even the sensitive issues like SARA (Ethnic, Religion, Racial and Communal conflicts can be freely discussed in the printed media. Thus freedom of expression is prevailing in Indonesia under the New Era government. 

  3. A biased review of biases in Twitter studies on political collective action

    Science.gov (United States)

    Cihon, Peter; Yasseri, Taha

    2016-08-01

    In recent years researchers have gravitated to Twitter and other social media platforms as fertile ground for empirical analysis of social phenomena. Social media provides researchers access to trace data of interactions and discourse that once went unrecorded in the offline world. Researchers have sought to use these data to explain social phenomena both particular to social media and applicable to the broader social world. This paper offers a minireview of Twitter-based research on political crowd behaviour. This literature offers insight into particular social phenomena on Twitter, but often fails to use standardized methods that permit interpretation beyond individual studies. Moreover, the literature fails to ground methodologies and results in social or political theory, divorcing empirical research from the theory needed to interpret it. Rather, investigations focus primarily on methodological innovations for social media analyses, but these too often fail to sufficiently demonstrate the validity of such methodologies. This minireview considers a small number of selected papers; we analyse their (often lack of) theoretical approaches, review their methodological innovations, and offer suggestions as to the relevance of their results for political scientists and sociologists.

  4. A biased review of biases in Twitter studies on political collective action

    Directory of Open Access Journals (Sweden)

    Peter Cihon

    2016-08-01

    Full Text Available In recent years researchers have gravitated to Twitter and other social media platforms as fertile ground for empirical analysis of social phenomena. Social media provides researchers access to trace data of interactions and discourse that once went unrecorded in the offline world. Researchers have sought to use these data to explain social phenomena both particular to social media and applicable to the broader social world. This paper offers a minireview of Twitter-based research on political crowd behaviour. This literature offers insight into particular social phenomena on Twitter, but often fails to use standardized methods that permit interpretation beyond individual studies. Moreover, the literature fails to ground methodologies and results in social or political theory, divorcing empirical research from the theory needed to interpret it. Rather, investigations focus primarily on methodological innovations for social media analyses, but these too often fail to sufficiently demonstrate the validity of such methodologies. This minireview considers a small number of selected papers; we analyse their (often lack of theoretical approaches, review their methodological innovations, and offer suggestions as to the relevance of their results for political scientists and sociologists.

  5. Line Balancing Using Largest Candidate Rule Algorithm In A Garment Industry: A Case Study

    Directory of Open Access Journals (Sweden)

    V. P.Jaganathan

    2014-12-01

    Full Text Available The emergence of fast changes in fashion has given rise to the need to shorten production cycle times in the garment industry. As effective usage of resources has a significant effect on the productivity and efficiency of production operations, garment manufacturers are urged to utilize their resources effectively in order to meet dynamic customer demand. This paper focuses specifically on line balancing and layout modification. The aim of assembly line balance in sewing lines is to assign tasks to the workstations, so that the machines of the workstation can perform the assigned tasks with a balanced loading. Largest Candidate Rule Algorithm (LCR has been deployed in this paper.

  6. Verbal Behavior and Politics.

    Science.gov (United States)

    Graber, Doris A.

    This book illustrates how and why knowledge of verbal behavior is important to an understanding of politics by analyzing and describing verbal behavior studies pertaining to politics. Chapters in the first part of the book discuss the various characteristics of verbal behavior: the importance of verbal behavior in politics, construction of…

  7. The Sexual Politics of Introducing Women's Studies: Memories and Reflections from North America and the United Kingdom, 1965-1995

    Science.gov (United States)

    Bird, Elizabeth

    2004-01-01

    The paper is part of a wider study into how women's studies was introduced in the academic curriculum in the United Kingdom, Canada and the USA. It looks at the sexual politics of the academy during the 1970s and 1980s, and at how they are now remembered. Women's studies was inextricably bound up in the politics of feminist activism in the period,…

  8. The political reference point: How geography shapes political identity.

    Directory of Open Access Journals (Sweden)

    Matthew Feinberg

    Full Text Available It is commonly assumed that how individuals identify on the political spectrum-whether liberal, conservative, or moderate-has a universal meaning when it comes to policy stances and voting behavior. But, does political identity mean the same thing from place to place? Using data collected from across the U.S. we find that even when people share the same political identity, those in "bluer" locations are more likely to support left-leaning policies and vote for Democratic candidates than those in "redder" locations. Because the meaning of political identity is inconsistent across locations, individuals who share the same political identity sometimes espouse opposing policy stances. Meanwhile, those with opposing identities sometimes endorse identical policy stances. Such findings suggest that researchers, campaigners, and pollsters must use caution when extrapolating policy preferences and voting behavior from political identity, and that animosity toward the other end of the political spectrum is sometimes misplaced.

  9. Risk prediction models for selection of lung cancer screening candidates: A retrospective validation study.

    Directory of Open Access Journals (Sweden)

    Kevin Ten Haaf

    2017-04-01

    Full Text Available Selection of candidates for lung cancer screening based on individual risk has been proposed as an alternative to criteria based on age and cumulative smoking exposure (pack-years. Nine previously established risk models were assessed for their ability to identify those most likely to develop or die from lung cancer. All models considered age and various aspects of smoking exposure (smoking status, smoking duration, cigarettes per day, pack-years smoked, time since smoking cessation as risk predictors. In addition, some models considered factors such as gender, race, ethnicity, education, body mass index, chronic obstructive pulmonary disease, emphysema, personal history of cancer, personal history of pneumonia, and family history of lung cancer.Retrospective analyses were performed on 53,452 National Lung Screening Trial (NLST participants (1,925 lung cancer cases and 884 lung cancer deaths and 80,672 Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial (PLCO ever-smoking participants (1,463 lung cancer cases and 915 lung cancer deaths. Six-year lung cancer incidence and mortality risk predictions were assessed for (1 calibration (graphically by comparing the agreement between the predicted and the observed risks, (2 discrimination (area under the receiver operating characteristic curve [AUC] between individuals with and without lung cancer (death, and (3 clinical usefulness (net benefit in decision curve analysis by identifying risk thresholds at which applying risk-based eligibility would improve lung cancer screening efficacy. To further assess performance, risk model sensitivities and specificities in the PLCO were compared to those based on the NLST eligibility criteria. Calibration was satisfactory, but discrimination ranged widely (AUCs from 0.61 to 0.81. The models outperformed the NLST eligibility criteria over a substantial range of risk thresholds in decision curve analysis, with a higher sensitivity for all models and a

  10. Risk prediction models for selection of lung cancer screening candidates: A retrospective validation study.

    Science.gov (United States)

    Ten Haaf, Kevin; Jeon, Jihyoun; Tammemägi, Martin C; Han, Summer S; Kong, Chung Yin; Plevritis, Sylvia K; Feuer, Eric J; de Koning, Harry J; Steyerberg, Ewout W; Meza, Rafael

    2017-04-01

    Selection of candidates for lung cancer screening based on individual risk has been proposed as an alternative to criteria based on age and cumulative smoking exposure (pack-years). Nine previously established risk models were assessed for their ability to identify those most likely to develop or die from lung cancer. All models considered age and various aspects of smoking exposure (smoking status, smoking duration, cigarettes per day, pack-years smoked, time since smoking cessation) as risk predictors. In addition, some models considered factors such as gender, race, ethnicity, education, body mass index, chronic obstructive pulmonary disease, emphysema, personal history of cancer, personal history of pneumonia, and family history of lung cancer. Retrospective analyses were performed on 53,452 National Lung Screening Trial (NLST) participants (1,925 lung cancer cases and 884 lung cancer deaths) and 80,672 Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial (PLCO) ever-smoking participants (1,463 lung cancer cases and 915 lung cancer deaths). Six-year lung cancer incidence and mortality risk predictions were assessed for (1) calibration (graphically) by comparing the agreement between the predicted and the observed risks, (2) discrimination (area under the receiver operating characteristic curve [AUC]) between individuals with and without lung cancer (death), and (3) clinical usefulness (net benefit in decision curve analysis) by identifying risk thresholds at which applying risk-based eligibility would improve lung cancer screening efficacy. To further assess performance, risk model sensitivities and specificities in the PLCO were compared to those based on the NLST eligibility criteria. Calibration was satisfactory, but discrimination ranged widely (AUCs from 0.61 to 0.81). The models outperformed the NLST eligibility criteria over a substantial range of risk thresholds in decision curve analysis, with a higher sensitivity for all models and a slightly

  11. An Overview Across the New Political Economy Literature

    OpenAIRE

    Luca Murrau

    2006-01-01

    This work presents a review of the literature on political process formation and the role of institutions on economic development. Models of citizen candidacy and candidate choice and equilibria under plurality rule elections are illustrated. Studies of the relation between institutional structure and paths of economic development are also reviewed.

  12. The Political Parties and Political Participation in Rivers State, Nigeria

    African Journals Online (AJOL)

    The Political Parties and Political Participation in Rivers State, Nigeria: A Case Study of 2015 General Elections. Goddey Wilson. Abstract. The study reviewed the activities of the political parties and its impact on voters' participation in the political activities in Rivers State. In pursuit of this objective, the study generated ...

  13. Politeness, emotion, and gender: A sociophonetic study of voice pitch modulation

    Science.gov (United States)

    Yuasa, Ikuko

    The present dissertation is a cross-gender and cross-cultural sociophonetic exploration of voice pitch characteristics utilizing speech data derived from Japanese and American speakers in natural conversations. The roles of voice pitch modulation in terms of the concepts of politeness and emotion as they pertain to culture and gender will be investigated herein. The research interprets the significance of my findings based on the acoustic measurements of speech data as they are presented in the ERB-rate scale (the most appropriate scale for human speech perception). The investigation reveals that pitch range modulation displayed by Japanese informants in two types of conversations is closely linked to types of politeness adopted by those informants. The degree of the informants' emotional involvement and expressions reflected in differing pitch range widths plays an important role in determining the relationship between pitch range modulation and politeness. The study further correlates the Japanese cultural concept of enryo ("self-restraint") with this phenomenon. When median values were examined, male and female pitch ranges across cultures did not conspicuously differ. However, sporadically occurring women's pitch characteristics which culturally differ in width and height of pitch ranges may create an 'emotional' perception of women's speech style. The salience of these pitch characteristics appears to be the source of the stereotypically linked sound of women's speech being identified as 'swoopy' or 'shrill' and thus 'emotional'. Such women's salient voice characteristics are interpreted in light of camaraderie/positive politeness. Women's use of conspicuous paralinguistic features helps to create an atmosphere of camaraderie. These voice pitch characteristics promote the establishment of a sense of camaraderie since they act to emphasize such feelings as concern, support, and comfort towards addressees, Moreover, men's wide pitch ranges are discussed in view

  14. Modern standardization case studies at the crossroads of technology, economics, and politics

    CERN Document Server

    Schneiderman, R

    2015-01-01

    Modern Standardization -- Case Studies at the Crossroads of Technology, Economics, and Politics covers the development of new technical standards, how these standards are typically triggered, and how they are submitted to standards development organizations (SDOs) for review and evaluation. It fills the gap in the shortage of reference material in the development of real-world standards. The increasing pace of innovation in technology has accelerated the competitive nature of standardization, particularly in emerging markets. Modern Standardization addresses these and other issues through a series of case studies in a format designed for academics and their engineering, business, and law school students.

  15. 47 CFR 76.1701 - Political file.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false Political file. 76.1701 Section 76.1701... CABLE TELEVISION SERVICE Documents to be Maintained for Inspection § 76.1701 Political file. (a) Every... (political file) of all requests for cablecast time made by or on behalf of a candidate for public office...

  16. Political Communication via the Media. ERIC Digest.

    Science.gov (United States)

    Aiex, Nola Kortner; Gottlieb, Stephen S.

    Noting that critics charge that news reporting focuses on the superficial, personal characteristics of candidates and ignores the issues underlying elections, this Digest examines the relationship between the political process and political communication through the media. It addresses the power of advertising, cyberspace political communication,…

  17. Maintaining Quality of Candidate Strains of Transgenic Mosquitoes for Studies in Containment Facilities in Disease Endemic Countries.

    Science.gov (United States)

    Mumford, John D; Leach, Adrian W; Benedict, Mark Q; Facchinelli, Luca; Quinlan, M Megan

    2018-01-01

    Transgenic mosquitoes are being developed as novel components of area-wide approaches to vector-borne disease control. Best practice is to develop these in phases, beginning with laboratory studies, before moving to field testing and inclusion in control programs, to ensure safety and prevent costly field testing of unsuitable strains. The process of identifying and developing good candidate strains requires maintenance of transgenic colonies over many generations in containment facilities. By working in disease endemic countries with target vector populations, laboratory strains may be developed and selected for properties that will enhance intended control efficacy in the next phase, while avoiding traits that introduce unnecessary risks. Candidate strains aiming toward field use must consistently achieve established performance criteria, throughout the process of scaling up from small study colonies to production of sufficient numbers for field testing and possible open release. Maintenance of a consistent quality can be demonstrated by a set of insect quality and insectary operating indicators, measured over time at predetermined intervals. These indicators: inform comparability of studies using various candidate strains at different times and locations; provide evidence of conformity relevant to compliance with terms of approval for regulated use; and can be used to validate some assumptions related to risk assessments covering the contained phase and for release into the environment.

  18. Women in Politics in Ghana: A Study on Local Government in the ...

    African Journals Online (AJOL)

    Women's participation in politics in Ghana is low, both at local and the national level. This reflects the global trend of women's participation in politics. This paper examines ways of deepening women's participation as assembly members in local government. It examines women's participation in politics with the aim of ...

  19. Results of the ESA study on psychological selection of astronaut candidates for Columbus missions II: Personality assessment

    Science.gov (United States)

    Goeters, Klaus-Martin; Fassbender, Christoph

    A unique composition of personality assessment methods was applied to a group of 97 ESA scientists and engineers. This group is highly comparable to real astronaut candidates with respect to age and education. The list of used tests includes personality questionnaires, problem solving in groups as well as a projective technique. The study goals were: 1. Verification of psychometric qualities and applicability of tests to the target group; 2. Search for culture-fair tests by which multi-national European groups can be examined; 3. Identification of test methods by which the adaptability of the candidates to the psycho-social stress of long-duration space flights can be assessed. Based on the empirical findings, a test battery was defined which can be used in the selection of ESA space personnel.

  20. Political Ideology, Confidence in Science, and Participation in Alzheimer Disease Research Studies.

    Science.gov (United States)

    Gabel, Matthew; Gooblar, Jonathan; Roe, Catherine M; Selsor, Natalie J; Morris, John C

    2018-01-18

    Americans' confidence in science varies based on their political ideology. This ideological divide has potentially important effects on citizens' engagement with and participation in clinical studies of Alzheimer disease (AD). A probability sample of 1583 Americans was surveyed about their willingness to participate in longitudinal AD research and about their political attitudes. These survey results were compared with a survey of 382 participants in a longitudinal AD study at the Knight Alzheimer Disease Research Center. Among Americans, more conservative ideology decreases willingness to participate in a hypothetical longitudinal cohort study of AD both directly and through its negative effect on confidence in science. The Knight Alzheimer Disease Research Center study participants expressed more liberal ideology and greater confidence in science than Americans in general. Of the survey respondents opposed to participation, over a quarter changed to neutral or positive if the study returned their research results to them. Clinical studies of AD are likely biased toward participants who are more liberal and have higher confidence in science than the general population. This recruitment bias may be reduced by lowering the trust demanded of participants through measures such as returning research results to participants.

  1. Putting newborn hearing screening on the political agenda in Belgium: local initiatives toward a community programme - a qualitative study.

    Science.gov (United States)

    Vos, Bénédicte; Lagasse, Raphaël; Levêque, Alain

    2014-07-01

    The Kingdon model, based on the convergence of three streams (problem, policy, and politics) and the opening of a policy window, analyses the process by which a health issue is placed on the political agenda. We used this model to document the political agenda-setting process of the newborn hearing screening programme in Belgium. A qualitative study based on a document review and on semi-directed interviews was carried out. The interviews were conducted with nine people who had played a role in putting the issue in question on the political agenda, and the documents reviewed included scientific literature and internal reports and publications from the newborn hearing screening programme. The thematic analysis of the data collected was carried out on the basis of the Kingdon model's three streams. The political agenda-setting of this screening programme was based on many factors. The problem stream included factors external to the context under study, such as the technological developments and the contribution of the scientific literature which led to the recommendation to provide newborn hearing screening. The two other streams (policy and politics) covered factors internal to the Belgian context. The fact that it was locally feasible with financial support, the network of doctors convinced of the need for newborn hearing screening, the drafting of various proposals, and the search for financing were all part of the policy stream. The Belgian political context and the policy opportunities concerning preventive medicine were identified as significant factors in the third stream. When these three streams converged, a policy window opened, allowing newborn hearing screening onto the political agenda and enabling the policy decision for its introduction. The advantage of applying the Kingdon model in our approach was the ability to demonstrate the political agenda-setting process, using the three streams. This made it possible to identify the many factors involved in

  2. Evaluation of 6 candidate genes on chromosome 11q23 for coeliac disease susceptibility: a case control study

    Directory of Open Access Journals (Sweden)

    Close Eimear

    2010-05-01

    Full Text Available Abstract Background Recent whole genome analysis and follow-up studies have identified many new risk variants for coeliac disease (CD, gluten intolerance. The majority of newly associated regions encode candidate genes with a clear functional role in T-cell regulation. Furthermore, the newly discovered risk loci, together with the well established HLA locus, account for less than 50% of the heritability of CD, suggesting that numerous additional loci remain undiscovered. Linkage studies have identified some well-replicated risk regions, most notably chromosome 5q31 and 11q23. Methods We have evaluated six candidate genes in one of these regions (11q23, namely CD3E, CD3D, CD3G, IL10RA, THY1 and IL18, as risk factors for CD using a 2-phase candidate gene approach directed at chromosome 11q. 377 CD cases and 349 ethnically matched controls were used in the initial screening, followed by an extended sample of 171 additional coeliac cases and 536 additional controls. Results Promotor SNPs (-607, -137 in the IL18 gene, which has shown association with several autoimmune diseases, initially suggested association with CD (P IL18-137/-607 also supported this effect, primarily due to one relatively rare haplotype IL18-607C/-137C (P Conclusion Haplotypes of the IL18 promotor region may contribute to CD risk, consistent with this cytokine's role in maintaining inflammation in active CD.

  3. Candidate proteins, metabolites and transcripts in the Biomarkers for Spinal Muscular Atrophy (BforSMA clinical study.

    Directory of Open Access Journals (Sweden)

    Richard S Finkel

    Full Text Available Spinal Muscular Atrophy (SMA is a neurodegenerative motor neuron disorder resulting from a homozygous mutation of the survival of motor neuron 1 (SMN1 gene. The gene product, SMN protein, functions in RNA biosynthesis in all tissues. In humans, a nearly identical gene, SMN2, rescues an otherwise lethal phenotype by producing a small amount of full-length SMN protein. SMN2 copy number inversely correlates with disease severity. Identifying other novel biomarkers could inform clinical trial design and identify novel therapeutic targets.To identify novel candidate biomarkers associated with disease severity in SMA using unbiased proteomic, metabolomic and transcriptomic approaches.A cross-sectional single evaluation was performed in 108 children with genetically confirmed SMA, aged 2-12 years, manifesting a broad range of disease severity and selected to distinguish factors associated with SMA type and present functional ability independent of age. Blood and urine specimens from these and 22 age-matched healthy controls were interrogated using proteomic, metabolomic and transcriptomic discovery platforms. Analyte associations were evaluated against a primary measure of disease severity, the Modified Hammersmith Functional Motor Scale (MHFMS and to a number of secondary clinical measures.A total of 200 candidate biomarkers correlate with MHFMS scores: 97 plasma proteins, 59 plasma metabolites (9 amino acids, 10 free fatty acids, 12 lipids and 28 GC/MS metabolites and 44 urine metabolites. No transcripts correlated with MHFMS.In this cross-sectional study, "BforSMA" (Biomarkers for SMA, candidate protein and metabolite markers were identified. No transcript biomarker candidates were identified. Additional mining of this rich dataset may yield important insights into relevant SMA-related pathophysiology and biological network associations. Additional prospective studies are needed to confirm these findings, demonstrate sensitivity to change with

  4. (Un- Political Ethics, (un- Ethical Politics

    Directory of Open Access Journals (Sweden)

    Wolff-Michael Roth

    2004-09-01

    Full Text Available Ethics and politics are normally con­sidered domains that do not mix, in fact, domains that have little to do with one another. In this article, I provide four factual fictions that show how at the university, research ethics and politics are intertwined. Politics appears to be used for the sole purpose of constructing and maintaining con­trol over the research process and its products. Ultimately, even ethics reviews of proposed research studies are caught up in the politics of power. URN: urn:nbn:de:0114-fqs0403357

  5. Ezekiel and the politics of Yahweh : a study in the kingship of God

    OpenAIRE

    Bechtel, Christopher Ronald

    2012-01-01

    The book of Ezekiel, like much of the Hebrew Bible, depicts Yahweh as a king. However, Ezekiel’s presentation of Yahweh’s kingship has been largely ignored by modern scholarship, and, when it has been addressed, has been categorized as a grand metaphor for Yahweh’s divine superiority. In contrast, this study argues that Yahweh’s kingship is a genuine political force, not merely a cipher for the exalted status of Israel’s deity. To answer the objection that ‘Yahweh is king’ i...

  6. The Political Economy of Funding Agricultural R&D in Papua New Guinea: A Case Study

    OpenAIRE

    Omuru, Eric; Kingwell, Ross S.

    2002-01-01

    Adequate and reliable funding of agricultural R&D is critical for sustaining research activities. A breakdown in funding arrangements can be detrimental to the long-term existence of R&D organisation/systems. This paper first, reviews the trends in funding arrangements for agricultural R&D in Papua New Guinea (PNG) in recent years. Second, the paper explores the extent to which political influence affects funding arrangements for agricultural R&D in PNG in terms of a case study. Third, with i...

  7. Exchange and Political Communication: Study at Regent Election of Soppeng District

    OpenAIRE

    Rosmawati, Rosmawati; Harifuddin, Harifuddin; Sudirman, Sudirman

    2015-01-01

    This paper aims to reveal the socio-political reality that is loaded with interest. The interest certainly are mutually-beneficial but often unbalanced political advantage. In this regard, politics always intersect or identical to ‘exchange' and ‘communication'. When interpreted in reverse, that isn't politics if it doesn't contain elements of ‘exchange' which must be preceded by a communication strategy its politicians. Specifi cally, this paper reveals the occurrence of a ‘political exchang...

  8. Summary Authoritarialism as Political Regime: Analysis of Historical and Empirical Studies

    Directory of Open Access Journals (Sweden)

    O. D. Grossman

    2016-01-01

    Full Text Available This article is devoted to the problems of existence of authoritarian regimes. The ambiguity of the resulting data determines the importance of the considered research. Authoritarianism is quite complicated socio-political phenomenon. For this reason, there are a lot of typologies and special features of authoritarianism as a political regime. Authoritarianism is not only a political regime, but it is also a set of social and political characteristics. Some countries, where the authoritarian tendencies dominate, are economically developed, and they have a competitive economy, but other countries, which are steeped in a reactionary authoritarian, do not develop properly. From the materials of this article it should be concluded that the political regime in Russia is principally authoritarian, or to be specific it is liberal authoritarian regime. This political regime has been established for the whole history of our country, and it is supported by paternalistic political culture and special mindset our nation.

  9. Placental genome and maternal-placental genetic interactions: a genome-wide and candidate gene association study of placental abruption.

    Directory of Open Access Journals (Sweden)

    Marie Denis

    Full Text Available While available evidence supports the role of genetics in the pathogenesis of placental abruption (PA, PA-related placental genome variations and maternal-placental genetic interactions have not been investigated. Maternal blood and placental samples collected from participants in the Peruvian Abruptio Placentae Epidemiology study were genotyped using Illumina's Cardio-Metabochip platform. We examined 118,782 genome-wide SNPs and 333 SNPs in 32 candidate genes from mitochondrial biogenesis and oxidative phosphorylation pathways in placental DNA from 280 PA cases and 244 controls. We assessed maternal-placental interactions in the candidate gene SNPS and two imprinted regions (IGF2/H19 and C19MC. Univariate and penalized logistic regression models were fit to estimate odds ratios. We examined the combined effect of multiple SNPs on PA risk using weighted genetic risk scores (WGRS with repeated ten-fold cross-validations. A multinomial model was used to investigate maternal-placental genetic interactions. In placental genome-wide and candidate gene analyses, no SNP was significant after false discovery rate correction. The top genome-wide association study (GWAS hits were rs544201, rs1484464 (CTNNA2, rs4149570 (TNFRSF1A and rs13055470 (ZNRF3 (p-values: 1.11e-05 to 3.54e-05. The top 200 SNPs of the GWAS overrepresented genes involved in cell cycle, growth and proliferation. The top candidate gene hits were rs16949118 (COX10 and rs7609948 (THRB (p-values: 6.00e-03 and 8.19e-03. Participants in the highest quartile of WGRS based on cross-validations using SNPs selected from the GWAS and candidate gene analyses had a 8.40-fold (95% CI: 5.8-12.56 and a 4.46-fold (95% CI: 2.94-6.72 higher odds of PA compared to participants in the lowest quartile. We found maternal-placental genetic interactions on PA risk for two SNPs in PPARG (chr3:12313450 and chr3:12412978 and maternal imprinting effects for multiple SNPs in the C19MC and IGF2/H19 regions

  10. Constructing Perceptions of Climate Change: a case study of regional political decision makers

    Science.gov (United States)

    Bray, D.

    2012-12-01

    This case study of climate change communications assesses the salient means of communication and the message adopted by regional political decision makers on the German Baltic coast. Realizing that cultural factors and local values (and not simply knowledge) are significant influences in explaining attitudes towards climate change, this analysis draws from the records of regional weather, from scientists with a specific focus on the region, from the political decision makers for that region, and the media message reaching the decision makers, ensuring all elements of the analysis are drawn from the same socioeconomic, geophysical, political and cultural context. This is important as the social dynamics surrounding the trust in science is of critical importance and, as such, all elements of the case study are specifically contained within a common context. If the utility of climate change knowledge is to prompt well conceived adaptation/mitigation strategies then the political decision process, or at least the perceptions shaping it, can best be understood by locating it within the world view of the decision makers involved in the production process. Using the results of two survey questionnaires, one of regional climate scientists and one of regional political decision makers, ten years of local weather records, and a summary of the message from mass media circulation, the discord in perceptions of regional climate change are quantitatively explored. The conclusions drawn from the analysis include, compared to the scientific assessment: The decision makers' perceptions of recent past differ from actual observations. The decision makers' perceptions of the future differ from scientific assessments. The decision makers tend to over estimate the magnitude of regional climate change and its impacts. The decision makers tend to over estimate the sense of immediacy for adaptation measures. The conclusions drawn suggest that in the regional political realm, it is often a

  11. From crucial issue to additional question. A study of the political debate about nuclear waste in Sweden 1976-2009

    International Nuclear Information System (INIS)

    Nord, Lars; Stur, Elisabeth

    2010-11-01

    The overall purpose of this paper is to investigate how the premises for the political decision processes in the issue of final disposal of the Swedish nuclear waste are affected by changes in the public opinion climate and global events. The paper therefore focuses on questions concerning how the national political debate leading up to decisions interacts with the media debate, and the public opinion dynamic that arises when the two debates relate to each other. Particular interest is devoted to the arguments and standpoints that occur in politics and media and how they refer to the prevailing public opinion situation and to conditions in the surrounding world of a political, legal, economic, ecological and technological nature. An analysis of the arenas and actors involved in the debates ought to provide valuable knowledge regarding how the political agenda has been formed at different points in time. The following questions are of central interest to the study: - What characterizes the parliamentary and the party political debate in the nuclear waste issue, and in what way have actors, standpoints and arguments changed over time? - What characterizes opinion formation and news reporting in the media in the nuclear waste issue and in what way have actors, standpoints and arguments changed over time? The course of the debate at four different times and in connection with four parliamentary elections during the period 1976-2009 is analyzed in the study. The subject of the analysis includes the four parliamentary parties the Centre Party, the Liberal Party, the Moderates and the Social Democrats. These four parties have been chosen because they have been represented in the Swedish Parliament during the entire period studied and are therefore reasonable to compare. The study has mainly been conducted as a qualitative textual analysis of public print, party documents and media content. The qualitative text analysis is complemented to some extent by other existing

  12. Water Scarcity and Political Instability in the Middle East - a multiscale study of Syria and its surrounding environment

    OpenAIRE

    Blaabjerg, Karoline; D'Costa, Lauren Lindsey; Grønbech, Peter; Hansen, Gultiano Hansen

    2015-01-01

    This thesis investigates the effect of water scarcity in the Middle East on political stability at the local, regional and global scale. Guided by a comprehensive Conceptual Framework encompassing theories and concepts of scales, national- human- and environmental security, the thesis is structured as a multiscale case study of Syria. The analyses each present a narrative about water scarcity and political stability specific to their scale. As such, it is established how water scarcity in the...

  13. Political Budget Cycles

    DEFF Research Database (Denmark)

    Aaskoven, Lasse; Lassen, David Dreyer

    2017-01-01

    The political budget cycle—how elections affect government fiscal policy—is one of the most studied subjects in political economy and political science. The key theoretical question is whether incumbent governments can time or structure public finances in ways that improve their chances of reelec......The political budget cycle—how elections affect government fiscal policy—is one of the most studied subjects in political economy and political science. The key theoretical question is whether incumbent governments can time or structure public finances in ways that improve their chances...... on political budget cycles have recently focused on conditions under which such cycles are likely to obtain. Much recent research focuses on subnational settings, allowing comparisons of governments in similar institutional environments, and a consensus on the presences of cycles in public finances...

  14. Political party affiliation, political ideology and mortality.

    Science.gov (United States)

    Pabayo, Roman; Kawachi, Ichiro; Muennig, Peter

    2015-05-01

    Ecological and cross-sectional studies have indicated that conservative political ideology is associated with better health. Longitudinal analyses of mortality are needed because subjective assessments of ideology may confound subjective assessments of health, particularly in cross-sectional analyses. Data were derived from the 2008 General Social Survey-National Death Index data set. Cox proportional analysis models were used to determine whether political party affiliation or political ideology was associated with time to death. Also, we attempted to identify whether self-reported happiness and self-rated health acted as mediators between political beliefs and time to death. In this analysis of 32,830 participants and a total follow-up time of 498,845 person-years, we find that political party affiliation and political ideology are associated with mortality. However, with the exception of independents (adjusted HR (AHR)=0.93, 95% CI 0.90 to 0.97), political party differences are explained by the participants' underlying sociodemographic characteristics. With respect to ideology, conservatives (AHR=1.06, 95% CI 1.01 to 1.12) and moderates (AHR=1.06, 95% CI 1.01 to 1.11) are at greater risk for mortality during follow-up than liberals. Political party affiliation and political ideology appear to be different predictors of mortality. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  15. Candidate gene polymorphisms study between human African trypanosomiasis clinical phenotypes in Guinea.

    Science.gov (United States)

    Kaboré, Justin Windingoudi; Ilboudo, Hamidou; Noyes, Harry; Camara, Oumou; Kaboré, Jacques; Camara, Mamadou; Koffi, Mathurin; Lejon, Veerle; Jamonneau, Vincent; MacLeod, Annette; Hertz-Fowler, Christiane; Belem, Adrien Marie Gaston; Matovu, Enock; Bucheton, Bruno; Sidibe, Issa

    2017-08-01

    Human African trypanosomiasis (HAT), a lethal disease induced by Trypanosoma brucei gambiense, has a range of clinical outcomes in its human host in West Africa: an acute form progressing rapidly to second stage, spontaneous self-cure and individuals able to regulate parasitaemia at very low levels, have all been reported from endemic foci. In order to test if this clinical diversity is influenced by host genetic determinants, the association between candidate gene polymorphisms and HAT outcome was investigated in populations from HAT active foci in Guinea. Samples were collected from 425 individuals; comprising of 232 HAT cases, 79 subjects with long lasting positive and specific serology but negative parasitology and 114 endemic controls. Genotypes of 28 SNPs in eight genes passed quality control and were used for an association analysis. IL6 rs1818879 allele A (p = 0.0001, OR = 0.39, CI95 = [0.24-0.63], BONF = 0.0034) was associated with a lower risk of progressing from latent infection to active disease. MIF rs36086171 allele G seemed to be associated with an increased risk (p = 0.0239, OR = 1.65, CI95 = [1.07-2.53], BONF = 0.6697) but did not remain significant after Bonferroni correction. Similarly MIF rs12483859 C allele seems be associated with latent infections (p = 0.0077, OR = 1.86, CI95 = [1.18-2.95], BONF = 0.2157). We confirmed earlier observations that APOL1 G2 allele (DEL) (p = 0.0011, OR = 2.70, CI95 = [1.49-4.91], BONF = 0.0301) is associated with a higher risk and APOL1 G1 polymorphism (p = 0.0005, OR = 0.45, CI95 = [0.29-0.70], BONF = 0.0129) with a lower risk of developing HAT. No associations were found with other candidate genes. Our data show that host genes are involved in modulating Trypanosoma brucei gambiense infection outcome in infected individuals from Guinea with IL6 rs1818879 being associated with a lower risk of progressing to active HAT. These results enhance our understanding of host-parasite interactions and, ultimately, may

  16. Social Studies Teacher Candidates' Opinions about Digital Citizenship and Its Place in Social Studies Teacher Training Program: A Comparison between the USA and Turkey

    Science.gov (United States)

    Karaduman, Hidir

    2017-01-01

    This research aims to determine and compare what social studies teacher candidates living in two different countries think about digital citizenship and its place within social studies and social studies teacher training program and to produce suggestions concerning digital citizenship education. Having a descriptive design, this research has…

  17. Public Sphere - Political Advertisement Relationship in Turkey: Analysing Political Advertisements of JDP in General Elections 2011

    Directory of Open Access Journals (Sweden)

    Erdal Dağtaş

    2015-09-01

    Full Text Available Public sphere is a social space, open to active individual access and free discussion, rescued from state intervention, where communicative action free from violence and individual benefits is undertaken; and rational-critical discourse is built. Political advertisement is the type advertising which aims at directing voters or the government to a particular action, having them adopt a certain view or approach. The concept of political advertising emerged with the practice of using commercial advertising techniques to promote a party, candidate or an idea. Justice and Development Party (JDP, has been ruling Turkey since 2002. The leader of the party is Prime Minister Recep Tayyip Erdoğan. It is a conservative party and has carried out some practices that could be regarded as negative. Anti-secular attitudes are also among these practices. Thus, analysing the political advertisements of JDP has proved to be interesting. Public sphere studies are mostly conducted through news stories and columns in media. In that sense, it is significant to analyse political advertisements in terms of public sphere. In this study, the political advertisements of the ruling Justice and Development Party (JDP in the process of Turkish General Parliamentary Election, 2011 have been analysed. The political advertisements in question have been analysed via Sabah newspaper. The reason for choosing Sabah is that it supports JDP as an example of partisan press. The samples have been taken from 2 weeks before the elections. Accordingly, as a full-page advertisement is published every day, 14 political advertisement analyses have been conducted in total. Political advertisements have been analysed using qualitative text analysis. As the study follows the path of public place-political advertising relationship, it finds meaning in itself.

  18. A Study of Teacher Stereotypes: How Do Tuition-Free Teacher Candidates and General Undergraduates Think about Middle School and University Teachers in China?

    Science.gov (United States)

    Zuo, Youxia; Zhao, Yufang; Peng, Chunhua; Chen, Youguo

    2017-01-01

    A tuition-free teacher candidate is an undergraduate who receives tuition-free teacher education and must work as a teacher in a middle school after their graduation. Tuition-free candidates are of the focus of many researchers; however, no study reports how tuition-free teacher candidates think about teachers. The present study explored stereotypes about middle school and university teachers held by teacher candidates. Specifically, we looked for the differences between the stereotypes held by the teacher candidates and general undergraduates. This study attempted to provide a potential tool to predict the actual willingness of teacher candidates to work as middle school teachers. University and middle school teachers were evaluated using descriptive phrases or words on a five-point Likert scale by 116 tuition-free teacher candidates and 155 general undergraduates. Exploratory factor analyses revealed a three-factor stereotype model including occupational cognition, occupational personality, and occupational emotion. Compared with general undergraduates, teacher candidates held more positive occupational personality and emotions toward middle school teachers; they held more negative occupational emotions toward university teachers. Further, the undergraduates' willingness to be middle school teachers positively correlated with positive occupational emotions and negatively correlated with negative occupational personality and emotions toward middle school teachers. This supported previous studies that individuals' professional willingness were influenced by their stereotypes about professions. PMID:28469587

  19. Using microarrays to identify positional candidate genes for QTL: the case study of ACTH response in pigs

    DEFF Research Database (Denmark)

    Jouffe, Vincent; Rowe, Suzanne; Liaubet, Laurence

    2009-01-01

    of 237 differentially expressed cDNA clones in adrenal tissue from two pig breeds, before and after treatment with adrenocorticotropic hormone (ACTH) Microarray studies can supplement QTL studies by suggesting potential candidate genes in the QTL regions, which by themselves are too large to provide...... this with information on published QTL. The starting point is a set of 237 differentially expressed cDNA clones in adrenal tissue from two pig breeds, before and after treatment with adrenocorticotropic hormone (ACTH) Results: Different approaches to localize the differentially expressed (DE) genes to the pig genome...

  20. The Effects of Majoring in Political Science on Political Efficacy

    Science.gov (United States)

    Dominguez, Casey B. K.; Smith, Keith W.; Williams, J. Michael

    2017-01-01

    This study tests, and finds support, for the hypotheses that a student who majors in political science will have stronger feelings of political competence and will be more willing to engage in hypothetical political actions than two peer groups: (a) those who major in other fields and (b) those who show an interest in politics but have not studied…

  1. Alteration of Political Belief by Non-invasive Brain Stimulation.

    Science.gov (United States)

    Chawke, Caroline; Kanai, Ryota

    2015-01-01

    People generally have imperfect introspective access to the mechanisms underlying their political beliefs, yet can confidently communicate the reasoning that goes into their decision making process. An innate desire for certainty and security in ones beliefs may play an important and somewhat automatic role in motivating the maintenance or rejection of partisan support. The aim of the current study was to clarify the role of the DLPFC in the alteration of political beliefs. Recent neuroimaging studies have focused on the association between the DLPFC (a region involved in the regulation of cognitive conflict and error feedback processing) and reduced affiliation with opposing political candidates. As such, this study used a method of non-invasive brain simulation (tRNS) to enhance activity of the bilateral DLPFC during the incorporation of political campaign information. These findings indicate a crucial role for this region in political belief formation. However, enhanced activation of DLPFC does not necessarily result in the specific rejection of political beliefs. In contrast to the hypothesis the results appear to indicate a significant increase in conservative values regardless of participant's initial political orientation and the political campaign advertisement they were exposed to.

  2. Civic political culture, participatory governance and political ...

    African Journals Online (AJOL)

    This study x-rayed the significance of civic political culture on participatory governance and its potentialities on political development. It adopted theoretical postulations in analyzing the subject matter. The analytical model showed a diagrammatic presentation of the relationship among participant culture features, elements ...

  3. Civic Political Culture, Participatory Governance and Political ...

    African Journals Online (AJOL)

    Prof

    Indexed African Journals Online: www.ajol.info as its potential contribution to political development in Nigeria-as it will be applicable to other developing countries of the world. This study provided theoretical postulations in analysing the notion of participatory governance, and linking the research problem (civic political ...

  4. The politics of local hospital reform: a case study of hospital reorganization following the 2002 Norwegian hospital reform.

    Science.gov (United States)

    Tjerbo, Trond

    2009-11-20

    The Norwegian hospital reform of 2002 was an attempt to make restructuring of hospitals easier by removing politicians from the decision-making processes. To facilitate changes seen as necessary but politically difficult, the central state took over ownership of the hospitals and stripped the county politicians of what had been their main responsibility for decades. This meant that decisions regarding hospital structure and organization were now being taken by professional administrators and not by politically elected representatives. The question raised here is whether this has had any effect on the speed of restructuring of the hospital sector. The empirical part is a case study of the restructuring process in Innlandet Hospital Trust (IHT), which was one of the largest enterprise established after the hospital reform and where the vision for restructuring was clearly set. Different sources of qualitative data are used in the analysis. These include interviews with key actors, observational data and document studies. The analysis demonstrates how the new professional leaders at first acted in accordance with the intentions of the hospital reform, but soon chose to avoid the more ambitious plans for restructuring the hospital structure and in fact reintroduced local politics into the decision-making process. The analysis further illustrates how local networks and engagement of political representatives from all levels of government complicated the decision-making process surrounding local structural reforms. Local political representatives teamed up with other actors and created powerful networks. At the same time, national politicians had incentives to involve themselves in the processes as supporters of the status quo. Because of the incentives that faced political actors and the controversial nature of major hospital reforms, the removal of local politicians and the centralization of ownership did not necessarily facilitate reforms in the hospital structure

  5. The politics of local hospital reform: a case study of hospital reorganization following the 2002 Norwegian hospital reform

    Directory of Open Access Journals (Sweden)

    Tjerbo Trond

    2009-11-01

    Full Text Available Abstract Background The Norwegian hospital reform of 2002 was an attempt to make restructuring of hospitals easier by removing politicians from the decision-making processes. To facilitate changes seen as necessary but politically difficult, the central state took over ownership of the hospitals and stripped the county politicians of what had been their main responsibility for decades. This meant that decisions regarding hospital structure and organization were now being taken by professional administrators and not by politically elected representatives. The question raised here is whether this has had any effect on the speed of restructuring of the hospital sector. Method The empirical part is a case study of the restructuring process in Innlandet Hospital Trust (IHT, which was one of the largest enterprise established after the hospital reform and where the vision for restructuring was clearly set. Different sources of qualitative data are used in the analysis. These include interviews with key actors, observational data and document studies. Results The analysis demonstrates how the new professional leaders at first acted in accordance with the intentions of the hospital reform, but soon chose to avoid the more ambitious plans for restructuring the hospital structure and in fact reintroduced local politics into the decision-making process. The analysis further illustrates how local networks and engagement of political representatives from all levels of government complicated the decision-making process surrounding local structural reforms. Local political representatives teamed up with other actors and created powerful networks. At the same time, national politicians had incentives to involve themselves in the processes as supporters of the status quo. Conclusion Because of the incentives that faced political actors and the controversial nature of major hospital reforms, the removal of local politicians and the centralization of ownership did

  6. Studies on reproductive stress caused by candidate Gram positive and Gram negative bacteria using model organism, Caenorhabditis elegans.

    Science.gov (United States)

    Sharika, Rajasekharan; Subbaiah, Priya; Balamurugan, Krishnaswamy

    2018-04-05

    Microbial association with a host using model system C. elegans have been widely studied based on factors such as host survival, the mode of infection, disease pathogenesis and the role of various players regulated during infection. The influence of pathogenic microorganism on reproduction and associated issues has not been explored fully. The present study focuses on the impact of bacterial infection on male reproductive parameters such as spermatogenesis and spermiogenesis, including physiological aspects like tail morphology defect and underlying molecular mechanisms that have been perturbed. In order to compare the consequence of infection caused by Gram positive and negative bacteria, Staphylococcus aureus and Vibrio alginolyticus were chosen as candidate pathogens, respectively. Microscopic observations revealed notable changes in tail morphology during 24 h of infection, as along with change in sperm size and activation. The Real Time-PCR results suggest the plausible down regulation of DBL-1/TGF-β pathway suggesting the morphological change in the tail. Shotgun proteomics further lead to the identification of MAG-1, Magonashi Protein a candidate regulatory player that affects spermatogenesis and HIF-1 that regulate during stress in both Gram positive and Gram negative infection. The protein-protein interaction with detected proteins revealed RACK-1 protein and mTOR pathway in S. aureus and V. alginolyticus respectively interacting with MAG-1 protein, which plays an important role in spermatogenesis termination in hermaphrodites during L4 to adult switch. This study paves a way to understand the candidate players that regulate reproduction during bacterial infection. Copyright © 2018 Elsevier B.V. All rights reserved.

  7. Online deliberation and beyond? A time-based and comparative study of Danish political debates online

    Directory of Open Access Journals (Sweden)

    Jakob Linaa Jensen

    2014-04-01

    Full Text Available This article discusses online political debates in Denmark over a time period from 2001 to 2011 and compares three different online debates in 2011. By taking a time-based as well as a comparative perspective, it examines whether online debates have come closer to deliberative ideals of democracy and how online debates differ in form and content. The article particularly addresses the interplay between everyday and political discussions. It is demonstrated that shifts between the two forms of discussion often happen abruptly and that even people who tend not to become involved politically in a formal sense happily discuss politics in more informal, non-political settings. Furthermore, the article expands our understanding of demographic differences in political participation in debates online. All this helps enhance and broaden our concept of democracy in an online setting. 

  8. Managing Perceptions of Public Opinion: Candidates' and Journalists' Reactions to the 1992 Polls.

    Science.gov (United States)

    Bauman, Sandra; Herbst, Susan

    1994-01-01

    Reports on an exploratory, interpretive study of campaign rhetoric, specifically the discourse surrounding opinion polls. Analyzes how candidates, their managers, and journalists reacted to polling results during the 1992 presidential race. Finds that political actors reify public opinion by speaking of survey data as though it were independent of…

  9. Has Political Science Ignored Religion?

    Science.gov (United States)

    Kettell, Steven

    2012-01-01

    A common complaint from political scientists involved in the study of religion is that religious issues have been largely overlooked by political science. Through a content analysis of leading political science and sociology journals from 2000 to 2010, this article considers the extent of this claim. The results show that political science…

  10. AXIOLOGICAL POTENTIAL OF POLITICAL NICKNAMES

    Directory of Open Access Journals (Sweden)

    SHUSTOVA IRINA NIKOLAEVNA

    2015-01-01

    Full Text Available The article is devoted to the study of axiological possibilities of political nicknames. Political nicknames are very expressive. They can be personal and impersonal. Some nicknames lose their primary meaning to become a part of evaluative political lexis. In the language of politics nicknames often serve not only as means of assessment, but also as ideological weapon.

  11. POLITICAL DIALOGUE AS THE BASIS OF FOREIGN POLICY: A CASE STUDY OF MODERN RUSSIAN-GERMAN RELATIONS

    Directory of Open Access Journals (Sweden)

    Natalia V. Zaytseva

    2014-01-01

    Full Text Available His article deals with political dialogue as the basis of the progressive development of interstate cooperation and one of the few ways to diminish interstate tensions without use of military force. With the growing list of new threats and challenges it is very important to work out an effective mechanism of interstate cooperation and to use it in foreign policy. Political dialogue helps to form the basis for cooperation between states to ensure the security, political and socio-economic stability of countries. Moreover, the political dialogue in its various forms is no longer a seldom-used private practice. It is the "all-encompassing reality" now the study of which is necessary for understanding of the social, economic, and humanitarian phenomena in the international relations. The author analyzes principles, functions, rules of constructive interstate dialogue, reflects the conditions of the development of a true political dialogue and reveals the situation of its "stylization" The provisions presented in this article are presented from the viewpoint of practical use in the development of a constructive foreign policy. At the same time the author points to their philosophical basis, identifies regularities and characteristics from the standpoint of philosophical knowledge. As a practical demonstration of carrying on the political dialogue the article presents a brief description of Russian-German political relations at the present stage. Bilateral relations between these two countries, based on the rich history, consilience of main positions in resolving of international problems, largely reflect the basic terms and principles of a competent political dialogue.

  12. Political Dialogue As The Basis Of Foreign Policy: A Case Study Of Modern Russian-German Relations

    Directory of Open Access Journals (Sweden)

    Natalia V. Zaytseva

    2014-01-01

    Full Text Available His article deals with political dialogue as the basis of the progressive development of interstate cooperation and one of the few ways to diminish interstate tensions without use of military force. With the growing list of new threats and challenges it is very important to work out an effective mechanism of interstate cooperation and to use it in foreign policy. Political dialogue helps to form the basis for cooperation between states to ensure the security, political and socio-economic stability of countries. Moreover, the political dialogue in its various forms is no longer a seldom-used private practice. It is the "all-encompassing reality" now the study of which is necessary for understanding of the social, economic, and humanitarian phenomena in the international relations. The author analyzes principles, functions, rules of constructive interstate dialogue, reflects the conditions of the development of a true political dialogue and reveals the situation of its "stylization" The provisions presented in this article are presented from the viewpoint of practical use in the development of a constructive foreign policy. At the same time the author points to their philosophical basis, identifies regularities and characteristics from the standpoint of philosophical knowledge. As a practical demonstration of carrying on the political dialogue the article presents a brief description of Russian-German political relations at the present stage. Bilateral relations between these two countries, based on the rich history, consilience of main positions in resolving of international problems, largely reflect the basic terms and principles of a competent political dialogue.

  13. Genome-Wide Association Studies Candidate Gene to Dual Modifier of Nonalcoholic Steatohepatitis and Atherosclerosis

    Directory of Open Access Journals (Sweden)

    Clint L. Miller, PhD

    2016-12-01

    Full Text Available Nonalcoholic steatohepatitis is a common disease involving chronic accumulation of fat and inflammation in the liver, often leading to advanced fibrosis, cirrhosis, and cancer. It is known that nonalcoholic steatohepatitis shares many features with atherosclerosis; however, there are still no effective therapeutics. In a recent study published in Nature, investigators demonstrated that mice lacking a high-density lipoprotein–associated gene were surprisingly protected from both steatohepatitis and atherosclerosis through the stabilization of the liver X receptor. This work reveals a timely candidate target for 2 highly prevalent cardiovascular diseases.

  14. Putting politics into perspective. A Study of the Implementation of EU public utilities directives

    International Nuclear Information System (INIS)

    Berglund, S.K.

    2009-01-01

    In the area of public utilities, the member states of the European Union (EU) have agreed on ambitious policies to open up markets for competition and to regulate these markets. To have the expected effect, these policies have to be implemented effectively. In this book it is demonstrated that this is problematic; difficulties appear already in the first step of transposing the directives into national legislation. The analysis of an original quantitative data set including all public utilities directives and their transposition in five member states - the Netherlands, Germany, the United Kingdom, Spain, and Greece - shows that almost two thirds of all cases are transposed after the deadlines that are included in the directives. In order to explain problems with the implementation of EU policies, three main types of variables are used in the literature, namely political, administrative, and institutional variables. In recent literature on transposition the focus is on political explanations. However, despite a surge of attention for transposition there is no consensus regarding which type of variable is most important. In this book the focus on political variables is addressed. It is examined if such a focus is well founded, and whether and how different types of variables combine in order to produce the transposition outcome. To this end, a novel approach is taken by developing a theoretical framework that applies implementation theory to transposition. In this framework the three types of variables in the literature on transposition are combined in one coherent framework. The theoretical framework is applied mainly in a case study setting. The transposition of two packages of directives in the fields of telecommunications and energy in the Netherlands, Germany and Greece is studied in detail. The main conclusion is that political factors play an important role for the timeliness of transposition, but that a number of 'mediating' variables of institutional

  15. POLITICAL CORRUPTION:  AN INTRODUCTORY STUDY ON TERMINOLOGY AND TYPOLOGY

    Directory of Open Access Journals (Sweden)

    Coskun Can Aktan

    2015-01-01

    Full Text Available The concept of corruption is generally used to mean all actions and behaviorsconstituting bribery, embezzlement, favoritism etc. It is important to note that,“corruption” is the name given to the certain types of corruption (mainly; bribery,embezzlement, favoritism, which has political characteristics. Political corruptionhas a wider meaning than corruption. In other words, political corruption is anumbrella concept which also includes corruption. This paper explores politicalcorruption, the abuse of public office for private gain. The goal of this paper is toprovide the terminology and especially typology of political corruption.

  16. An Audience Study on PTT Gossiping and the Politics of Truth

    Directory of Open Access Journals (Sweden)

    Szuping Lin

    2017-10-01

    Full Text Available Through the audience research approach of in-depth interviews with users of the internet PTT Gossiping forum, this papers employs the concept of “politics of truth” to examine the “gossip” culture in the forum as well as the operation of truth/power politics within it. User interviews provide understandings of the meanings, operations, subject positions and social practices of the forum and how they interact with power politics in society. The gossip forum has expanded what gossip culture represents from collective imagination to social practices, renewing the perspectives derived from it, while engaging in a dialogue with the concept of politics of truth.

  17. Evaluation of 6 candidate genes on chromosome 11q23 for coeliac disease susceptibility: a case control study.

    LENUS (Irish Health Repository)

    Brophy, Karen

    2010-01-01

    BACKGROUND: Recent whole genome analysis and follow-up studies have identified many new risk variants for coeliac disease (CD, gluten intolerance). The majority of newly associated regions encode candidate genes with a clear functional role in T-cell regulation. Furthermore, the newly discovered risk loci, together with the well established HLA locus, account for less than 50% of the heritability of CD, suggesting that numerous additional loci remain undiscovered. Linkage studies have identified some well-replicated risk regions, most notably chromosome 5q31 and 11q23. METHODS: We have evaluated six candidate genes in one of these regions (11q23), namely CD3E, CD3D, CD3G, IL10RA, THY1 and IL18, as risk factors for CD using a 2-phase candidate gene approach directed at chromosome 11q. 377 CD cases and 349 ethnically matched controls were used in the initial screening, followed by an extended sample of 171 additional coeliac cases and 536 additional controls. RESULTS: Promotor SNPs (-607, -137) in the IL18 gene, which has shown association with several autoimmune diseases, initially suggested association with CD (P < 0.05). Follow-up analyses of an extended sample supported the same, moderate effect (P < 0.05) for one of these. Haplotype analysis of IL18-137\\/-607 also supported this effect, primarily due to one relatively rare haplotype IL18-607C\\/-137C (P < 0.0001), which was independently associated in two case-control comparisons. This same haplotype has been noted in rheumatoid arthritis. CONCLUSION: Haplotypes of the IL18 promotor region may contribute to CD risk, consistent with this cytokine\\'s role in maintaining inflammation in active CD.

  18. Evaluation of 6 candidate genes on chromosome 11q23 for coeliac disease susceptibility: a case control study

    LENUS (Irish Health Repository)

    Brophy, Karen

    2010-05-17

    Abstract Background Recent whole genome analysis and follow-up studies have identified many new risk variants for coeliac disease (CD, gluten intolerance). The majority of newly associated regions encode candidate genes with a clear functional role in T-cell regulation. Furthermore, the newly discovered risk loci, together with the well established HLA locus, account for less than 50% of the heritability of CD, suggesting that numerous additional loci remain undiscovered. Linkage studies have identified some well-replicated risk regions, most notably chromosome 5q31 and 11q23. Methods We have evaluated six candidate genes in one of these regions (11q23), namely CD3E, CD3D, CD3G, IL10RA, THY1 and IL18, as risk factors for CD using a 2-phase candidate gene approach directed at chromosome 11q. 377 CD cases and 349 ethnically matched controls were used in the initial screening, followed by an extended sample of 171 additional coeliac cases and 536 additional controls. Results Promotor SNPs (-607, -137) in the IL18 gene, which has shown association with several autoimmune diseases, initially suggested association with CD (P < 0.05). Follow-up analyses of an extended sample supported the same, moderate effect (P < 0.05) for one of these. Haplotype analysis of IL18-137\\/-607 also supported this effect, primarily due to one relatively rare haplotype IL18-607C\\/-137C (P < 0.0001), which was independently associated in two case-control comparisons. This same haplotype has been noted in rheumatoid arthritis. Conclusion Haplotypes of the IL18 promotor region may contribute to CD risk, consistent with this cytokine\\'s role in maintaining inflammation in active CD.

  19. The Association Study between Twenty One Polymorphisms in Seven Candidate Genes and Coronary Heart Diseases in Chinese Han Population.

    Directory of Open Access Journals (Sweden)

    Barrak F Alobeidy

    Full Text Available Previous genome-wide association studies (GWAS in multiple populations identified several genetic loci for coronary heart diseases (CHD. Here we utilized a 2-stage candidate gene association strategy in Chinese Han population to shed light on the putative association between several metabolic-related candidate genes and CHD. At the 1(st stage, 190 patients with CHD and 190 controls were genotyped through the MassARRAY platform. At the 2(nd stage, a larger sample including 400 patients and 392 controls was genotyped by the High Resolution Melt (HRM method to confirm or rule out the associations with CHD. MLXIP expression level was quantified by the real time PCR in 65 peripheral blood samples. From the 21 studied single nucleotide polymorphisms (SNPs of seven candidate genes: MLXIPL, MLXIP, MLX, ADIPOR1, VDR, SREBF1 and NR1H3, only one tag SNP rs4758685 (T→C was found to be statistically associated with CHD (P-value = 0.02, Odds ratio (OR of 0.83. After adjustment for the age, sex, lipid levels and diabetes, the association remained significant (P-value = 0.03. After adjustment for the hypertension, P-value became 0.20 although there was a significant difference in the allele distribution between the CHD patients with hypertension and the controls (P-value = 0.04, 406 vs 582. In conclusion, among the 21 tested SNPs, we identified a novel association between rs4758685 of MLXIP gene and CHD. The C allele of common variant rs4758685 interacted with hypertension, and was found to be protective against CHD in both allelic and genotypic models in Chinese Han population.

  20. Office Politics

    Science.gov (United States)

    Storm, Paula; Kelly, Robert; deVries, Susann

    2008-01-01

    People and organizations are inherently political. Library workplace environments have zones of tension and dynamics just like any corporation, often leading to the formation of political camps. These different cliques influence productivity and work-related issues and, at worst, give meetings the feel of the Camp David negotiations. Politics are…

  1. Moral politics

    DEFF Research Database (Denmark)

    Rapp, Carolin; Traunmüller, Richard; Freitag, Markus

    2014-01-01

    This article combines the research strands of moral politics and political behavior by focusing on the effect of individual and contextual religiosity on individual vote decisions in popular initiatives and public referenda concerning morally charged issues. We rely on a total of 13 surveys with 1...... American research on moral politics, direct democracies, and the public role of religion....

  2. Politics of religious minoritisation and glocalisation: notes towards a study of religious networks of transnational

    Directory of Open Access Journals (Sweden)

    Joanildo Burity

    2015-08-01

    Full Text Available This article offers a preliminary analytical framework for the study of one of the main forms of global expression of religious movements in the contemporary scenario and its specific impact on the public sphere: the involvement of networks of social and political activism at translocal, trasnational and global levels. This is done through the analysis of the relationship between religion and globalisation, with particular attention to Christian groups, stressing two sets of processes: first, the dynamics of visibility and latency within these experiences; and second, the convergence betweenprocesses of minoritisation and imbrication of local and global (which will be developed though the concept of glocalisation. The study will be conducted as a comparative analysis of existing networks between Brazil, Argentina and the United Kingdom. 

  3. The Truth in Political Advertising: A Modest Proposal.

    Science.gov (United States)

    Schier, Richard F.

    1980-01-01

    Proposes that political candidates, particularly those running for lesser offices, be required to make their party affiliation visible. This would protect the voter from misrepresentation and help stop the erosion of political parties. (CK)

  4. The political domain appears simpler to the politically extreme than to political moderates

    NARCIS (Netherlands)

    Lammers, J.; Koch, Alex; Conway, Paul; Brandt, M.J.

    2018-01-01

    How does political preference affect categorization in the political domain? Eight studies demonstrate that people on both ends of the political spectrum—strong Republicans and strong Democrats—form simpler and more clustered categories of political stimuli than do moderates and neutrals. This

  5. Cross-study and cross-omics comparisons of three nephrotoxic compounds reveal mechanistic insights and new candidate biomarkers

    International Nuclear Information System (INIS)

    Matheis, Katja A.; Com, Emmanuelle; Gautier, Jean-Charles; Guerreiro, Nelson; Brandenburg, Arnd; Gmuender, Hans; Sposny, Alexandra; Hewitt, Philip; Amberg, Alexander; Boernsen, Olaf; Riefke, Bjoern; Hoffmann, Dana; Mally, Angela; Kalkuhl, Arno; Suter, Laura; Dieterle, Frank; Staedtler, Frank

    2011-01-01

    The European InnoMed-PredTox project was a collaborative effort between 15 pharmaceutical companies, 2 small and mid-sized enterprises, and 3 universities with the goal of delivering deeper insights into the molecular mechanisms of kidney and liver toxicity and to identify mechanism-linked diagnostic or prognostic safety biomarker candidates by combining conventional toxicological parameters with 'omics' data. Mechanistic toxicity studies with 16 different compounds, 2 dose levels, and 3 time points were performed in male Crl: WI(Han) rats. Three of the 16 investigated compounds, BI-3 (FP007SE), Gentamicin (FP009SF), and IMM125 (FP013NO), induced kidney proximal tubule damage (PTD). In addition to histopathology and clinical chemistry, transcriptomics microarray and proteomics 2D-DIGE analysis were performed. Data from the three PTD studies were combined for a cross-study and cross-omics meta-analysis of the target organ. The mechanistic interpretation of kidney PTD-associated deregulated transcripts revealed, in addition to previously described kidney damage transcript biomarkers such as KIM-1, CLU and TIMP-1, a number of additional deregulated pathways congruent with histopathology observations on a single animal basis, including a specific effect on the complement system. The identification of new, more specific biomarker candidates for PTD was most successful when transcriptomics data were used. Combining transcriptomics data with proteomics data added extra value.

  6. Genome-wide association study identified genetic variations and candidate genes for plant architecture component traits in Chinese upland cotton.

    Science.gov (United States)

    Su, Junji; Li, Libei; Zhang, Chi; Wang, Caixiang; Gu, Lijiao; Wang, Hantao; Wei, Hengling; Liu, Qibao; Huang, Long; Yu, Shuxun

    2018-03-01

    Thirty significant associations between 22 SNPs and five plant architecture component traits in Chinese upland cotton were identified via GWAS. Four peak SNP loci located on chromosome D03 were simultaneously associated with more plant architecture component traits. A candidate gene, Gh_D03G0922, might be responsible for plant height in upland cotton. A compact plant architecture is increasingly required for mechanized harvesting processes in China. Therefore, cotton plant architecture is an important trait, and its components, such as plant height, fruit branch length and fruit branch angle, affect the suitability of a cultivar for mechanized harvesting. To determine the genetic basis of cotton plant architecture, a genome-wide association study (GWAS) was performed using a panel composed of 355 accessions and 93,250 single nucleotide polymorphisms (SNPs) identified using the specific-locus amplified fragment sequencing method. Thirty significant associations between 22 SNPs and five plant architecture component traits were identified via GWAS. Most importantly, four peak SNP loci located on chromosome D03 were simultaneously associated with more plant architecture component traits, and these SNPs were harbored in one linkage disequilibrium block. Furthermore, 21 candidate genes for plant architecture were predicted in a 0.95-Mb region including the four peak SNPs. One of these genes (Gh_D03G0922) was near the significant SNP D03_31584163 (8.40 kb), and its Arabidopsis homologs contain MADS-box domains that might be involved in plant growth and development. qRT-PCR showed that the expression of Gh_D03G0922 was upregulated in the apical buds and young leaves of the short and compact cotton varieties, and virus-induced gene silencing (VIGS) proved that the silenced plants exhibited increased PH. These results indicate that Gh_D03G0922 is likely the candidate gene for PH in cotton. The genetic variations and candidate genes identified in this study lay a foundation

  7. Civic Education as a Collaborative Dimension of Social Studies Education in Attainment of Political Ethics in Nigeria

    Science.gov (United States)

    Dania, Peter

    2015-01-01

    The paper investigated Civic Education as a collaborative dimension of Social Studies Education in attainment of political ethics in Nigeria. The study adopted the survey research design. The sample for the study consisted of 580 Social Studies teachers selected from thirty secondary schools in the three senatorial districts of Delta State. The…

  8. Genetic determinants of facial clefting: analysis of 357 candidate genes using two national cleft studies from Scandinavia.

    Directory of Open Access Journals (Sweden)

    Astanand Jugessur

    Full Text Available Facial clefts are common birth defects with a strong genetic component. To identify fetal genetic risk factors for clefting, 1536 SNPs in 357 candidate genes were genotyped in two population-based samples from Scandinavia (Norway: 562 case-parent and 592 control-parent triads; Denmark: 235 case-parent triads.We used two complementary statistical methods, TRIMM and HAPLIN, to look for associations across these two national samples. TRIMM tests for association in each gene by using multi-SNP genotypes from case-parent triads directly without the need to infer haplotypes. HAPLIN on the other hand estimates the full haplotype distribution over a set of SNPs and estimates relative risks associated with each haplotype. For isolated cleft lip with or without cleft palate (I-CL/P, TRIMM and HAPLIN both identified significant associations with IRF6 and ADH1C in both populations, but only HAPLIN found an association with FGF12. For isolated cleft palate (I-CP, TRIMM found associations with ALX3, MKX, and PDGFC in both populations, but only the association with PDGFC was identified by HAPLIN. In addition, HAPLIN identified an association with ETV5 that was not detected by TRIMM.Strong associations with seven genes were replicated in the Scandinavian samples and our approach effectively replicated the strongest previously known association in clefting--with IRF6. Based on two national cleft cohorts of similar ancestry, two robust statistical methods and a large panel of SNPs in the most promising cleft candidate genes to date, this study identified a previously unknown association with clefting for ADH1C and provides additional candidates and analytic approaches to advance the field.

  9. Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study

    Science.gov (United States)

    Fox, Ervin R.; Young, J. Hunter; Li, Yali; Dreisbach, Albert W.; Keating, Brendan J.; Musani, Solomon K.; Liu, Kiang; Morrison, Alanna C.; Ganesh, Santhi; Kutlar, Abdullah; Ramachandran, Vasan S.; Polak, Josef F.; Fabsitz, Richard R.; Dries, Daniel L.; Farlow, Deborah N.; Redline, Susan; Adeyemo, Adebowale; Hirschorn, Joel N.; Sun, Yan V.; Wyatt, Sharon B.; Penman, Alan D.; Palmas, Walter; Rotter, Jerome I.; Townsend, Raymond R.; Doumatey, Ayo P.; Tayo, Bamidele O.; Mosley, Thomas H.; Lyon, Helen N.; Kang, Sun J.; Rotimi, Charles N.; Cooper, Richard S.; Franceschini, Nora; Curb, J. David; Martin, Lisa W.; Eaton, Charles B.; Kardia, Sharon L.R.; Taylor, Herman A.; Caulfield, Mark J.; Ehret, Georg B.; Johnson, Toby; Chakravarti, Aravinda; Zhu, Xiaofeng; Levy, Daniel; Munroe, Patricia B.; Rice, Kenneth M.; Bochud, Murielle; Johnson, Andrew D.; Chasman, Daniel I.; Smith, Albert V.; Tobin, Martin D.; Verwoert, Germaine C.; Hwang, Shih-Jen; Pihur, Vasyl; Vollenweider, Peter; O'Reilly, Paul F.; Amin, Najaf; Bragg-Gresham, Jennifer L.; Teumer, Alexander; Glazer, Nicole L.; Launer, Lenore; Zhao, Jing Hua; Aulchenko, Yurii; Heath, Simon; Sõber, Siim; Parsa, Afshin; Luan, Jian'an; Arora, Pankaj; Dehghan, Abbas; Zhang, Feng; Lucas, Gavin; Hicks, Andrew A.; Jackson, Anne U.; Peden, John F.; Tanaka, Toshiko; Wild, Sarah H.; Rudan, Igor; Igl, Wilmar; Milaneschi, Yuri; Parker, Alex N.; Fava, Cristiano; Chambers, John C.; Kumari, Meena; JinGo, Min; van der Harst, Pim; Kao, Wen Hong Linda; Sjögren, Marketa; Vinay, D.G.; Alexander, Myriam; Tabara, Yasuharu; Shaw-Hawkins, Sue; Whincup, Peter H.; Liu, Yongmei; Shi, Gang; Kuusisto, Johanna; Seielstad, Mark; Sim, Xueling; Nguyen, Khanh-Dung Hoang; Lehtimäki, Terho; Matullo, Giuseppe; Wu, Ying; Gaunt, Tom R.; Charlotte Onland-Moret, N.; Cooper, Matthew N.; Platou, Carl G.P.; Org, Elin; Hardy, Rebecca; Dahgam, Santosh; Palmen, Jutta; Vitart, Veronique; Braund, Peter S.; Kuznetsova, Tatiana; Uiterwaal, Cuno S.P.M.; Campbell, Harry; Ludwig, Barbara; Tomaszewski, Maciej; Tzoulaki, Ioanna; Palmer, Nicholette D.; Aspelund, Thor; Garcia, Melissa; Chang, Yen-Pei C.; O'Connell, Jeffrey R.; Steinle, Nanette I.; Grobbee, Diederick E.; Arking, Dan E.; Hernandez, Dena; Najjar, Samer; McArdle, Wendy L.; Hadley, David; Brown, Morris J.; Connell, John M.; Hingorani, Aroon D.; Day, Ian N.M.; Lawlor, Debbie A.; Beilby, John P.; Lawrence, Robert W.; Clarke, Robert; Collins, Rory; Hopewell, Jemma C.; Ongen, Halit; Bis, Joshua C.; Kähönen, Mika; Viikari, Jorma; Adair, Linda S.; Lee, Nanette R.; Chen, Ming-Huei; Olden, Matthias; Pattaro, Cristian; Hoffman Bolton, Judith A.; Köttgen, Anna; Bergmann, Sven; Mooser, Vincent; Chaturvedi, Nish; Frayling, Timothy M.; Islam, Muhammad; Jafar, Tazeen H.; Erdmann, Jeanette; Kulkarni, Smita R.; Bornstein, Stefan R.; Grässler, Jürgen; Groop, Leif; Voight, Benjamin F.; Kettunen, Johannes; Howard, Philip; Taylor, Andrew; Guarrera, Simonetta; Ricceri, Fulvio; Emilsson, Valur; Plump, Andrew; Barroso, Inês; Khaw, Kay-Tee; Weder, Alan B.; Hunt, Steven C.; Bergman, Richard N.; Collins, Francis S.; Bonnycastle, Lori L.; Scott, Laura J.; Stringham, Heather M.; Peltonen, Leena; Perola, Markus; Vartiainen, Erkki; Brand, Stefan-Martin; Staessen, Jan A.; Wang, Thomas J.; Burton, Paul R.; SolerArtigas, Maria; Dong, Yanbin; Snieder, Harold; Wang, Xiaoling; Zhu, Haidong; Lohman, Kurt K.; Rudock, Megan E.; Heckbert, Susan R.; Smith, Nicholas L.; Wiggins, Kerri L.; Shriner, Daniel; Veldre, Gudrun; Viigimaa, Margus; Kinra, Sanjay; Prabhakaran, Dorairajan; Tripathy, Vikal; Langefeld, Carl D.; Rosengren, Annika; Thelle, Dag S.; MariaCorsi, Anna; Singleton, Andrew; Forrester, Terrence; Hilton, Gina; McKenzie, Colin A.; Salako, Tunde; Iwai, Naoharu; Kita, Yoshikuni; Ogihara, Toshio; Ohkubo, Takayoshi; Okamura, Tomonori; Ueshima, Hirotsugu; Umemura, Satoshi; Eyheramendy, Susana; Meitinger, Thomas; Wichmann, H.-Erich; Cho, Yoon Shin; Kim, Hyung-Lae; Lee, Jong-Young; Scott, James; Sehmi, Joban S.; Zhang, Weihua; Hedblad, Bo; Nilsson, Peter; Smith, George Davey; Wong, Andrew; Narisu, Narisu; Stančáková, Alena; Raffel, Leslie J.; Yao, Jie; Kathiresan, Sekar; O'Donnell, Chris; Schwartz, Steven M.; Arfan Ikram, M.; Longstreth, Will T.; Seshadri, Sudha; Shrine, Nick R.G.; Wain, Louise V.; Morken, Mario A.; Swift, Amy J.; Laitinen, Jaana; Prokopenko, Inga; Zitting, Paavo; Cooper, Jackie A.; Humphries, Steve E.; Danesh, John; Rasheed, Asif; Goel, Anuj; Hamsten, Anders; Watkins, Hugh; Bakker, Stephan J.L.; van Gilst, Wiek H.; Janipalli, Charles S.; Radha Mani, K.; Yajnik, Chittaranjan S.; Hofman, Albert; Mattace-Raso, Francesco U.S.; Oostra, Ben A.; Demirkan, Ayse; Isaacs, Aaron; Rivadeneira, Fernando; Lakatta, Edward G.; Orru, Marco; Scuteri, Angelo; Ala-Korpela, Mika; Kangas, Antti J.; Lyytikäinen, Leo-Pekka; Soininen, Pasi; Tukiainen, Taru; Würz, Peter; Twee-Hee Ong, Rick; Dörr, Marcus; Kroemer, Heyo K.; Völker, Uwe; Völzke, Henry; Galan, Pilar; Hercberg, Serge; Lathrop, Mark; Zelenika, Diana; Deloukas, Panos; Mangino, Massimo; Spector, Tim D.; Zhai, Guangju; Meschia, James F.; Nalls, Michael A.; Sharma, Pankaj; Terzic, Janos; Kranthi Kumar, M.J.; Denniff, Matthew; Zukowska-Szczechowska, Ewa; Wagenknecht, Lynne E.; Fowkes, Gerald R.; Charchar, Fadi J.; Schwarz, Peter E.H.; Hayward, Caroline; Guo, Xiuqing; Bots, Michiel L.; Brand, Eva; Samani, Nilesh J.; Polasek, Ozren; Talmud, Philippa J.; Nyberg, Fredrik; Kuh, Diana; Laan, Maris; Hveem, Kristian; Palmer, Lyle J.; van der Schouw, Yvonne T.; Casas, Juan P.; Mohlke, Karen L.; Vineis, Paolo; Raitakari, Olli; Wong, Tien Y.; Shyong Tai, E.; Laakso, Markku; Rao, Dabeeru C.; Harris, Tamara B.; Morris, Richard W.; Dominiczak, Anna F.; Kivimaki, Mika; Marmot, Michael G.; Miki, Tetsuro; Saleheen, Danish; Chandak, Giriraj R.; Coresh, Josef; Navis, Gerjan; Salomaa, Veikko; Han, Bok-Ghee; Kooner, Jaspal S.; Melander, Olle; Ridker, Paul M.; Bandinelli, Stefania; Gyllensten, Ulf B.; Wright, Alan F.; Wilson, James F.; Ferrucci, Luigi; Farrall, Martin; Tuomilehto, Jaakko; Pramstaller, Peter P.; Elosua, Roberto; Soranzo, Nicole; Sijbrands, Eric J.G.; Altshuler, David; Loos, Ruth J.F.; Shuldiner, Alan R.; Gieger, Christian; Meneton, Pierre; Uitterlinden, Andre G.; Wareham, Nicholas J.; Gudnason, Vilmundur; Rettig, Rainer; Uda, Manuela; Strachan, David P.; Witteman, Jacqueline C.M.; Hartikainen, Anna-Liisa; Beckmann, Jacques S.; Boerwinkle, Eric; Boehnke, Michael; Larson, Martin G.; Järvelin, Marjo-Riitta; Psaty, Bruce M.; Abecasis, Gonçalo R.; Elliott, Paul; van Duijn , Cornelia M.; Newton-Cheh, Christopher

    2011-01-01

    The prevalence of hypertension in African Americans (AAs) is higher than in other US groups; yet, few have performed genome-wide association studies (GWASs) in AA. Among people of European descent, GWASs have identified genetic variants at 13 loci that are associated with blood pressure. It is unknown if these variants confer susceptibility in people of African ancestry. Here, we examined genome-wide and candidate gene associations with systolic blood pressure (SBP) and diastolic blood pressure (DBP) using the Candidate Gene Association Resource (CARe) consortium consisting of 8591 AAs. Genotypes included genome-wide single-nucleotide polymorphism (SNP) data utilizing the Affymetrix 6.0 array with imputation to 2.5 million HapMap SNPs and candidate gene SNP data utilizing a 50K cardiovascular gene-centric array (ITMAT-Broad-CARe [IBC] array). For Affymetrix data, the strongest signal for DBP was rs10474346 (P= 3.6 × 10−8) located near GPR98 and ARRDC3. For SBP, the strongest signal was rs2258119 in C21orf91 (P= 4.7 × 10−8). The top IBC association for SBP was rs2012318 (P= 6.4 × 10−6) near SLC25A42 and for DBP was rs2523586 (P= 1.3 × 10−6) near HLA-B. None of the top variants replicated in additional AA (n = 11 882) or European-American (n = 69 899) cohorts. We replicated previously reported European-American blood pressure SNPs in our AA samples (SH2B3, P= 0.009; TBX3-TBX5, P= 0.03; and CSK-ULK3, P= 0.0004). These genetic loci represent the best evidence of genetic influences on SBP and DBP in AAs to date. More broadly, this work supports that notion that blood pressure among AAs is a trait with genetic underpinnings but also with significant complexity. PMID:21378095

  10. Comparing Political Journalism

    DEFF Research Database (Denmark)

    Comparing Political Journalism is a systematic, in-depth study of the factors that shape and influence political news coverage today. Using techniques drawn from the growing field of comparative political communication, an international group of contributors analyse political news content drawn f...... Comparing Political Journalism offers an unparalleled scope in assessing the implications for the ongoing transformation of Western media systems, and addresses core concepts of central importance to students and scholars of political communication world-wide.......Comparing Political Journalism is a systematic, in-depth study of the factors that shape and influence political news coverage today. Using techniques drawn from the growing field of comparative political communication, an international group of contributors analyse political news content drawn...... from newspapers, television news, and news websites from 16 countries, to assess what kinds of media systems are most conducive to producing quality journalism. Underpinned by key conceptual themes, such as the role that the media are expected to play in democracies and quality of coverage...

  11. Carotenoid content and root color of cultivated carrot: a candidate-gene association study using an original broad unstructured population.

    Directory of Open Access Journals (Sweden)

    Matthieu Jourdan

    Full Text Available Accumulated in large amounts in carrot, carotenoids are an important product quality attribute and therefore a major breeding trait. However, the knowledge of carotenoid accumulation genetic control in this root vegetable is still limited. In order to identify the genetic variants linked to this character, we performed an association mapping study with a candidate gene approach. We developed an original unstructured population with a broad genetic basis to avoid the pitfall of false positive detection due to population stratification. We genotyped 109 SNPs located in 17 candidate genes – mostly carotenoid biosynthesis genes – on 380 individuals, and tested the association with carotenoid contents and color components. Total carotenoids and β-carotene contents were significantly associated with genes zeaxanthin epoxydase (ZEP, phytoene desaturase (PDS and carotenoid isomerase (CRTISO while α-carotene was associated with CRTISO and plastid terminal oxidase (PTOX genes. Color components were associated most significantly with ZEP. Our results suggest the involvement of the couple PDS/PTOX and ZEP in carotenoid accumulation, as the result of the metabolic and catabolic activities respectively. This study brings new insights in the understanding of the carotenoid pathway in non-photosynthetic organs.

  12. Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle.

    Science.gov (United States)

    Mota, R R; Guimarães, S E F; Fortes, M R S; Hayes, B; Silva, F F; Verardo, L L; Kelly, M J; de Campos, C F; Guimarães, J D; Wenceslau, R R; Penitente-Filho, J M; Garcia, J F; Moore, S

    2017-12-01

    We performed a genome-wide mapping for the age at first calving (AFC) with the goal of annotating candidate genes that regulate fertility in Nellore cattle. Phenotypic data from 762 cows and 777k SNP genotypes from 2,992 bulls and cows were used. Single nucleotide polymorphism (SNP) effects based on the single-step GBLUP methodology were blocked into adjacent windows of 1 Megabase (Mb) to explain the genetic variance. SNP windows explaining more than 0.40% of the AFC genetic variance were identified on chromosomes 2, 8, 9, 14, 16 and 17. From these windows, we identified 123 coding protein genes that were used to build gene networks. From the association study and derived gene networks, putative candidate genes (e.g., PAPPA, PREP, FER1L6, TPR, NMNAT1, ACAD10, PCMTD1, CRH, OPKR1, NPBWR1 and NCOA2) and transcription factors (TF) (STAT1, STAT3, RELA, E2F1 and EGR1) were strongly associated with female fertility (e.g., negative regulation of luteinizing hormone secretion, folliculogenesis and establishment of uterine receptivity). Evidence suggests that AFC inheritance is complex and controlled by multiple loci across the genome. As several windows explaining higher proportion of the genetic variance were identified on chromosome 14, further studies investigating the interaction across haplotypes to better understand the molecular architecture behind AFC in Nellore cattle should be undertaken. © 2017 Blackwell Verlag GmbH.

  13. Preliminary geological study in kabupaten Pamekasan area to support the selection of candidate site of nuclear desalination plant

    International Nuclear Information System (INIS)

    Ngadenin; Lilik Subiantoro; Kurnia Setiawan Widana

    2014-01-01

    The area around the southern coast Pamekasan is one of the candidates for the alternatives location of nuclear desalination plant site. In 1949 around Sampang Madura ever tectonic earthquake measuring 5 on the Richter scale with its epicenter on land. Tectonic earthquake with epicenter on land is likely related to the presence of active faults on the Madura island. Location prospective nuclear desalination plant site should be away or free of active faults. The study aimed to obtain geological information and find out the characteristics of tectonics including active fault to support site studies of nuclear desalination plant on the island of Madura. The method used is the geological mapping scale, 1 : 50,000. Lithology in the area along the south coast district Pamekasan is alluvium Holocene age and conglomerate units of Pleistocene age. There were no indications of active faults in the region. Candidates site at this location is less attractive in terms of geotechnical foundation as can be ascertained bedrock will be found sufficient in that building construction will require expensive. (author)

  14. Genome-wide association study to identify candidate loci and genes for Mn toxicity tolerance in rice.

    Directory of Open Access Journals (Sweden)

    Asis Shrestha

    Full Text Available Manganese (Mn is an essential micro-nutrient for plants, but flooded rice fields can accumulate high levels of Mn2+ leading to Mn toxicity. Here, we present a genome-wide association study (GWAS to identify candidate loci conferring Mn toxicity tolerance in rice (Oryza sativa L.. A diversity panel of 288 genotypes was grown in hydroponic solutions in a greenhouse under optimal and toxic Mn concentrations. We applied a Mn toxicity treatment (5 ppm Mn2+, 3 weeks at twelve days after transplanting. Mn toxicity caused moderate damage in rice in terms of biomass loss and symptom formation despite extremely high shoot Mn concentrations ranging from 2.4 to 17.4 mg g-1. The tropical japonica subpopulation was more sensitive to Mn toxicity than other subpopulations. Leaf damage symptoms were significantly correlated with Mn uptake into shoots. Association mapping was conducted for seven traits using 416741 single nucleotide polymorphism (SNP markers using a mixed linear model, and detected six significant associations for the traits shoot manganese concentration and relative shoot length. Candidate regions contained genes coding for a heavy metal transporter, peroxidase precursor and Mn2+ ion binding proteins. The significant marker SNP-2.22465867 caused an amino acid change in a gene (LOC_Os02g37170 with unknown function. This study demonstrated significant natural variation in rice for Mn toxicity tolerance and the possibility of using GWAS to unravel genetic factors responsible for such complex traits.

  15. Space, politics, and the political

    OpenAIRE

    dikec, mustafa

    1987-01-01

    International audience; Introduction Geography and politics'', Gottmann wrote in 1980, ``have long been in search of each other'' (page 11). Debates in the literature suggest not only that they have found each other, but also that the encounter has instigated, notably in the last decade or so, a body of literature seeking to think space politically, and to think politics spatially. This is not to suggest that previous work on space was apolitical, nor to suggest that previous work on politics...

  16. Constituency Orientation in Irish Politics

    DEFF Research Database (Denmark)

    Kusche, Isabel

    2017-01-01

    The constituency orientation of Irish politicians is a recurring topic in Irish political science. Its analysis has predominantly focused on TDs. This article uses a content analysis of candidate video statements in the general election 2016 in order to assess the strength of constituency...... this pattern, indicated by the weak constituency orientation in Dublin and Cork constituencies. Results also indicate differences between parties and some political statuses, while the gender of the candidates is of no relevance. Although the material does not permit a clear distinction between effects...... of political culture and short-term considerations, taken together the results indicate that localism in Irish politics matters, but in more complicated ways than usually depicted....

  17. Developing Research and Teaching Resources for the Study of Organizational Communication in Political Settings.

    Science.gov (United States)

    Graber, Doris A.

    It is unfortunate that the field of organizational communication has neglected communication in political settings, because the bulk of students enrolled in social science curricula are likely to work in public or semipublic institutions. Problems unique to the political setting stem from the fact that most public agencies must tailor their…

  18. Temperature, Cultural Masculinity, and Domestic Political Violence. A Cross-National Study

    NARCIS (Netherlands)

    Van de Vliert, E.; Schwartz, S.H; Huismans, S.E.; Hofstede, G.; Daan, S

    Cross-national data sets were used to examine the association between ambient temperature and internal political violence in 136 countries between 1948 and 1977. Political riots and armed attacks occur more frequently in warm countries than in both cold and hot countries, after controlling for

  19. A Study of Politeness Strategies Used by the National University of ...

    African Journals Online (AJOL)

    Another common feature found as a strategy by NUL students to express politeness is the extension of kinship terms to all lecturers (even non - kins). I finally argue that with urbanization, caused by exodus from cities to rural areas and vice versa, modernization, and adoption of Western way of life, the polite linguistic and ...

  20. The politics of reproduction.

    Science.gov (United States)

    Ginsburg, F; Rapp, R

    1991-01-01

    The topic of human reproduction encompasses events throughout the human and especially female life-cycle as well as ideas and practices surrounding fertility, birth, and child care. Most of the scholarship on the subject, up through the 1960s, was based on cross-cultural surveys focused on the beliefs, norms, and values surrounding reproductive behaviors. Multiple methodologies and subspecialties, and fields like social history, human biology, and demography were utilized for the analysis. The concept of the politics of reproduction synthesizes local and global perspectives. The themes investigated include: the concept of reproduction, population control, and the internationalization of state and market interests (new reproductive technologies); social movements and contested domains; medicalization and its discontents; fertility and its control; adolescence and teen pregnancy; birth; birth attendants; the construction of infancy and the politics of child survival; rethinking the demographic transition; networks of nurturance; and meanings of menopause. The medicalization of reproduction is a central issue of studies of birth, midwifery, infertility, and reproductive technologies. Scholars have also analyzed different parts of the female life-cycle as medical problems. Other issues worth analysis include the internationalization of adoption and child care workers; the crisis of infertility of low-income and minority women who are not candidates for expensive reproductive technologies; the concerns of women at high risk for HIV whose cultural status depends on their fertility; questions of reproduction concerning, lesbians and gay men (artificial insemination and discrimination in child rearing); the study of menopause; and fatherhood. New discourse analysis is used to analyze state eugenic policies; conflicts over Western neocolonial influences in which women's status as childbearers represent nationalist interests; fundamentalist attacks on abortion rights; and

  1. Professional and political reflections on the 'grand round': a critical case study.

    Science.gov (United States)

    Cooper, Dan; Mercer, Dave

    2017-09-07

    This case study presents a critical reflective account of a change to working practices in one NHS Trust. To promote quality care and effective clinical decision making, a 'grand round' was introduced in the orthopaedic department. Implementation presented frustrations and challenges for members of the multidisciplinary team. These are explored using transformative learning and critical reflection, enabling connections to be made between micro-level interactions of clinical care and macro-level structures that frame healthcare services. It is important that nurses recognise the escalating impact of a neoliberal agenda, and new public management, that drive UK health policy and politics. The value base of nursing is threatened by a corporate culture that measures performance in terms of institutional targets rather than individual care.

  2. Performing Politics

    Directory of Open Access Journals (Sweden)

    Troy R. E. Paddock

    2016-01-01

    Full Text Available Walter Benjamin’s observation that fascism turns politics into aesthetics is, by now, a well-worn idea. This article argues that Benjamin’s critique of politics can apply just as much to the modern democratic politics of the United States. Borrowing from Benjamin, Jürgen Habermas, and Carl Schmitt, this article suggests that modern political discourse in the United States does not follow the classical liberal ideal of rational discourse in the marketplace of ideas within the public sphere. Instead, contemporary politics has become spectacle where images and slogans replace thought and debate in a 24/7 news cycle and political infotainment programs. The result is that progressives and conservatives have their own political “ecospheres” which enable them to have their own perspective reinforced, and debate is replaced by straw man arguments and personal attacks.

  3. Interpersonal politics: the role of terror management and attachment processes in shaping political preferences.

    Science.gov (United States)

    Weise, David R; Pyszczynski, Tom; Cox, Cathy R; Arndt, Jamie; Greenberg, Jeff; Solomon, Sheldon; Kosloff, Spee

    2008-05-01

    Research on terror management theory (TMT) indicates that reminders of death affect political attitudes, but political orientation only sometimes moderates these effects. We propose that secure relationships are associated with values of tolerance and compassion, thus orienting people toward liberalism; insecure attachments are associated with more rigid and absolutist values that orient people toward conservatism. Given that attachment relationships become especially active when security needs are heightened, we predicted that mortality salience would be an important factor in understanding the relationship between attachment processes and political orientation. Supporting these ideas, Study 1 showed that after a mortality-salience manipulation, securely attached participants increased their support for a liberal presidential candidate, and less securely attached participants increased their support for a conservative presidential candidate. In Study 2, a secure-relationship prime following a mortality-salience manipulation engendered a less violent approach to the problem of terrorism than did a neutral-relationship prime. We discuss the interaction of TMT processes and individual differences in attachment in shaping political preferences.

  4. Teaching Politically without Political Correctness.

    Science.gov (United States)

    Graff, Gerald

    2000-01-01

    Discusses how to bring political issues into the classroom, highlighting the influence of local context and noting conservative and liberal criticisms of political correctness. Suggests the need for a different idea of how to teach politically from the advocacy pedagogy advanced by recent critical educators, explaining that bringing students into…

  5. New discursive strategies within Political Communication. Case study: Parliamentary Parties in Romania

    Directory of Open Access Journals (Sweden)

    Cristina Ariton-Gelan

    2013-07-01

    Full Text Available The development of new technologies, implicitely that of Internet contributed to the reconfiguration of the political communication field. In this respect, politicians report themselves to an electorate that is more detached from institutionalized politics and political ideologies, electorate that has the possibility to participate to debating alternative forms of the political, through some social movements and through online forums. Generally, new media created the possibility that journalists and media production agencies imagine more dynamic media formats from the point of view of interaction with citizens and visual strategies. Within the new context coming from the relation between politician, media and electorate, the Internet, through its functions, generates a special kind of „political communication management”.

  6. Guide of attributes of the nurse's political competence: a methodological study.

    Science.gov (United States)

    Melo, Wesley Soares de; Oliveira, Paulo Jorge Ferreira de; Monteiro, Flávia Paula Magalhães; Santos, Francisca Carla Dos Angelos; Silva, Maria Janaína Nogueira da; Calderon, Carolina Jimenez; Fonseca, Lilian Nara Amaral da; Simão, Ana Adélia Chaves

    2017-01-01

    To build and validate a guide of attributes of the nurse's political competence. Methodological research. This study comprised the construction of the instrument through literature review; experts validation of pre-established attributes for composing the guide; and clinical validation in the nurses work environment/reality. The data collection took place in the months from August to October 2014, and the analysis was based on the content analysis of Bardin and use of Epi info 3.5. All ethical precepts have been complied with. From 29 attributes found in the literature, 25 have been validated by experts. Clinical/practical validation involved the participation of 43 nurses, who observed that the attributes are not articulated with the professional practices developed by them. The attributes of the nurse's political competence were identified with support of literature. It is concluded that the professionals still have limited and fragmented perception of political competence, expressing difficulty/limitation. Construir e validar um guia de atributos da competência política do enfermeiro. Pesquisa metodológica. O estudo compreendeu a construção do instrumento por meio de revisão da literatura; validação, por especialistas, dos atributos preestabelecidos para composição do guia; e validação clínica no ambiente/realidade de trabalho dos enfermeiros. A coleta dos dados ocorreu nos meses de agosto a outubro de 2014, e a análise baseou-se na análise de conteúdo de Bardin e utilização do Epi info 3.5. Foram respeitados todos os preceitos éticos. Dos 29 atributos encontrados na literatura, 25 foram validados pelos especialistas. A validação clínica/prática envolveu a participação de 43 enfermeiros, os quais observaram que os atributos não apresentam articulação com as práticas profissionais por eles desenvolvidas. Identificados os atributos da competência política do enfermeiro com apoio da literatura. Conclui-se que os profissionais ainda

  7. School of Political Science

    Directory of Open Access Journals (Sweden)

    A. D. Voskresensky

    2014-01-01

    Full Text Available Out of all the departments of political sciences in Russia - the Department at MGIMO-University is probably the oldest one. In fact it is very young. While MGIMO-University is celebrating its 70th anniversary the Department of Political Sciences turns 15. Despite the fact that political analyst is a relatively new profession in Russia, it acquired a legal standing only in the 1990s, the political science school at MGIMO-University is almost as old as the university itself. Unlike many other universities, focused on the training teachers of political science or campaign managers MGIMO-University has developed its own unique political science school of "full cycle", where students grow into political sciences from a zero level up to the highest qualifications as teachers and researchers, and campaign managers, consultants and practitioners. The uniqueness of the school of political science at MGIMO-University allows its institutional incarnation -the Department of Political Science - to offer prospective studentsa training in a wide range of popular specialties and specializations, while ensuring a deep theoretical and practical basis of the training. Studying at MGIMO-University traditionally includes enhanced linguistic component (at least two foreign languages. For students of international relations and political science learning foreign languages is particularly important.It allows not only to communicate, but also to produce expertise and knowledge in foreign languages.

  8. Political learning among youth

    DEFF Research Database (Denmark)

    Solhaug, Trond; Kristensen, Niels Nørgaard

    2014-01-01

    This article focuses on students’ first political learning and explores the research question, what dynamic patterns of political learning can be explored among a selection of young, diverse Danish students’ first political interests? The authors use theories of learning in their analytical...... approach to students´ stories. A group of 10 young students who claim a certain political interest and attend a social studies course in Danish upper secondary school were selected to interview. A “life story approach” is used in the interviews and in the analytical approach. Findings: contrary to many...... “single agent studies in the tradition” of political socialization, the authors find that all students display a complex pattern of political influence. The influence from various agents like school, family, media and peers is also rather complex. Students are not passive recipients of influence...

  9. Political Identitiy Of A Minority Group Study Of Noaulu State Community Survival Strategy In Sepa Central Maluku

    Directory of Open Access Journals (Sweden)

    Abdul Manaf Tubaka

    2017-01-01

    Full Text Available This study has five objectives. Firstly why religion of Noaulu can survive in the Midst of social change Increasingly. Secondly how the relationship that has developed between Naulu Community and the government maintains Reviews their identity. Thirdly how the government treats the minority of Noaulu along with Reviews their existence. Fourthly how the factors of social culture and politics influence the sustainability of the political dynamic of Noaulu community in Sepa. Sixthly how the shared value that has been applied by Noaulu community and the political identity as addressing the political dynamic of the social structure of society. This study used a qualitative method with the approach of verstehen or understanding to dig the data is from inside inside view of values or meanings that comes from the subject of the study through the individuals and the phenomenon of political identity in Noaulu community. Data were gained through the observation depth interview and documentation. The analysis of data begins with making the abstraction Categorization coding checking the correctness of the data and then interpreting the data is and drawing the conclusion. Results of the study Showed that firstly the religion Becomes the adhesive strength of identity that Allows the sustainability of Noaulu Community. Secondly each of the minority community it will adapt Strategically to the power of the state in the relations of Resistance in compliance. Thirdly the New Order State has made the space plurality of race religion and ethnicity in the political stability that is rigid Thus it turns off the articulation space of religion and cultural identity of each minority group. Fourthly factors of social cultural political and give impact in the area of social relations culture and politics as well. Fifthly each of minority community always possess shared values such as high trust commitment to the religion loyaity to the group and the value of reciprocity

  10. Gendering transnational party politics

    DEFF Research Database (Denmark)

    Kantola, Johanna; Rolandsen-Agustín, Lise

    2016-01-01

    research traditions, we build toward an analytical framework to study gender and transnational party politics. Our empirical analysis focuses on two policy issues, the economic crisis and the sexual and reproductive health and rights, analyzing European Parliament reports, debates and voting on the issues......In this article, we analyze transnational party politics in the European Union from a gender perspective. This is a subject that has been neglected both by mainstream European studies on party politics and by gender scholars who work on political parties. Drawing on the insights of these two...... right axis and, at the same time, internal divisions within party groups affect policy output....

  11. Nuclear Magnetic Resonance (NMR Study for the Detection and Quantitation of Cholesterol in HSV529 Therapeutic Vaccine Candidate

    Directory of Open Access Journals (Sweden)

    Rahima Khatun

    Full Text Available This study describes the NMR-based method to determine the limit of quantitation (LOQ and limit of detection (LOD of cholesterol, a process-related impurity in the replication-deficient Herpes Simplex Virus (HSV type 2 candidate vaccine HSV529. Three signature peaks from the 1D 1H NMR of a cholesterol reference spectrum were selected for the identification of cholesterol. The LOQ for a cholesterol working standard was found to be 1 μg/mL, and the LOD was found to be 0.1 μg/mL. The identity of cholesterol, separated from the formulation of growth supplement by thin layer chromatography (TLC, was confirmed by 1D 1H NMR and 2D 1H-13C HSQC NMR. The three signature peaks of cholesterol were detected only in a six-times concentrated sample of HSV529 candidate vaccine sample and not in the single dose HSV529 vaccine sample under similar experimental conditions. Taken together, the results demonstrated that NMR is a direct method that can successfully identify and quantify cholesterol in viral vaccine samples, such as HSV529, and as well as in the growth supplement used during the upstream stages of HSV529 manufacturing. Keywords: Herpes simplex virus type 2 (HSV-2, Viral vaccine, NMR, Residuals, LOD and LOQ, TLC, Growth supplement

  12. A Selected Reaction Monitoring Mass Spectrometry Protocol for Validation of Proteomic Biomarker Candidates in Studies of Psychiatric Disorders.

    Science.gov (United States)

    Reis-de-Oliveira, Guilherme; Garcia, Sheila; Guest, Paul C; Cassoli, Juliana S; Martins-de-Souza, Daniel

    2017-01-01

    Most biomarker candidates arising from proteomic studies of psychiatric disorders have not progressed for use in clinical studies due to insufficient validation steps. Here we describe a selective reaction monitoring mass spectrometry (SRM-MS) approach that could be used as a follow-up validation tool of proteins identified in blood serum or plasma. This protocol specifically covers the stages of peptide selection and optimization. The increasing application of SRM-MS should enable fast, sensitive, and robust methods with the potential for use in clinical studies involving sampling of serum or plasma. Understanding the molecular mechanisms and identifying potential biomarkers for risk assessment, diagnosis, prognosis, and prediction of drug response goes toward the implementation of translational medicine strategies for improved treatment of patients with psychiatric disorders and other debilitating diseases.

  13. A study on homogeneity of the IAEA candidate reference materials for microanalysis and analytical support in the certification of these materials

    International Nuclear Information System (INIS)

    Dybczynski, R.; Danko, B.; Polkowska-Motrenko, H.

    2002-01-01

    In this paper a study on homogeneity of new IAEA candidate reference materials: IAEA 338 Lichen and IAEA 413 Algae in small (ca.10 mg) samples as well as some data contributing to certification of these materials are presented. (author)

  14. Training of Critical Thinking Skills in Teacher Candidates and Placebo Effect: A Quasi-Experimental Study

    Science.gov (United States)

    Demirbag, Betul; Unisen, Ali; Yesilyurt, Abdullah

    2016-01-01

    Problem Statement: In recent years many different studies have examined critical thinking disposition; however, these studies focus on investigating the variables that are related to this subject. There are actually few empirical studies in the literature. It is clear that there is a need for experimental research in order to comprehend the…

  15. [Political psychology].

    Science.gov (United States)

    Resch, Mária; Bella, Tamás

    2013-04-21

    In Hungary one can mostly find references to the psychological processes of politics in the writings of publicists, public opinion pollsters, philosophers, social psychologists, and political analysts. It would be still important if not only legal scientists focusing on political institutions or sociologist-politologists concentrating on social structures could analyse the psychological aspects of political processes; but one could also do so through the application of the methods of political psychology. The authors review the history of political psychology, its position vis-à-vis other fields of science and the essential interfaces through which this field of science, which is still to be discovered in Hungary, connects to other social sciences. As far as its methodology comprising psycho-biographical analyses, questionnaire-based queries, cognitive mapping of interviews and statements are concerned, it is identical with the psychiatric tools of medical sciences. In the next part of this paper, the focus is shifted to the essence and contents of political psychology. Group dynamics properties, voters' attitudes, leaders' personalities and the behavioural patterns demonstrated by them in different political situations, authoritativeness, games, and charisma are all essential components of political psychology, which mostly analyses psychological-psychiatric processes and also involves medical sciences by relying on cognitive and behavioural sciences. This paper describes political psychology, which is basically part of social sciences, still, being an interdisciplinary science, has several ties to medical sciences through psychological and psychiatric aspects.

  16. Politics and health outcomes.

    Science.gov (United States)

    Navarro, Vicente; Muntaner, Carles; Borrell, Carme; Benach, Joan; Quiroga, Agueda; Rodríguez-Sanz, Maica; Vergés, Núria; Pasarín, M Isabel

    2006-09-16

    The aim of this study was to examine the complex interactions between political traditions, policies, and public health outcomes, and to find out whether different political traditions have been associated with systematic patterns in population health over time. We analysed a number of political, economic, social, and health variables over a 50-year period, in a set of wealthy countries belonging to the Organisation for Economic Co-operation and Development (OECD). Our findings support the hypothesis that the political ideologies of governing parties affect some indicators of population health. Our analysis makes an empirical link between politics and policy, by showing that political parties with egalitarian ideologies tend to implement redistributive policies. An important finding of our research is that policies aimed at reducing social inequalities, such as welfare state and labour market policies, do seem to have a salutary effect on the selected health indicators, infant mortality and life expectancy at birth.

  17. Establishing Political Deliberation Systems

    DEFF Research Database (Denmark)

    Rose, Jeremy; Sæbø, Øystein

    2008-01-01

    The extension and transformation of political participation is dependent on widespread deliberation supported by information and communication technologies.  The most commonly found examples of these eParticipation systems are political discussion forums.  Though much of the discussion...... of these technologies is conducted in the eGovernment and (particularly) the eDemocracy literature, political discussion forums present a distinct set of design and management challenges which relate directly to IS concerns. In this article we analyze problems in establishing political deliberation systems under five...... headings: stakeholder engagement, web platform design, web platform management, political process re-shaping and evaluation and improvement. We review the existing literature and present a longitudinal case study of a political discussion forum: the Norwegian DemokratiTorget (Democracy Square).  We define...

  18. Genome-Wide Association Study Identifying Candidate Genes Influencing Important Agronomic Traits of Flax (Linum usitatissimum L.) Using SLAF-seq

    Science.gov (United States)

    Xie, Dongwei; Dai, Zhigang; Yang, Zemao; Sun, Jian; Zhao, Debao; Yang, Xue; Zhang, Liguo; Tang, Qing; Su, Jianguang

    2018-01-01

    Flax (Linum usitatissimum L.) is an important cash crop, and its agronomic traits directly affect yield and quality. Molecular studies on flax remain inadequate because relatively few flax genes have been associated with agronomic traits or have been identified as having potential applications. To identify markers and candidate genes that can potentially be used for genetic improvement of crucial agronomic traits, we examined 224 specimens of core flax germplasm; specifically, phenotypic data for key traits, including plant height, technical length, number of branches, number of fruits, and 1000-grain weight were investigated under three environmental conditions before specific-locus amplified fragment sequencing (SLAF-seq) was employed to perform a genome-wide association study (GWAS) for these five agronomic traits. Subsequently, the results were used to screen single nucleotide polymorphism (SNP) loci and candidate genes that exhibited a significant correlation with the important agronomic traits. Our analyses identified a total of 42 SNP loci that showed significant correlations with the five important agronomic flax traits. Next, candidate genes were screened in the 10 kb zone of each of the 42 SNP loci. These SNP loci were then analyzed by a more stringent screening via co-identification using both a general linear model (GLM) and a mixed linear model (MLM) as well as co-occurrences in at least two of the three environments, whereby 15 final candidate genes were obtained. Based on these results, we determined that UGT and PL are candidate genes for plant height, GRAS and XTH are candidate genes for the number of branches, Contig1437 and LU0019C12 are candidate genes for the number of fruits, and PHO1 is a candidate gene for the 1000-seed weight. We propose that the identified SNP loci and corresponding candidate genes might serve as a biological basis for improving crucial agronomic flax traits. PMID:29375606

  19. Science Teacher Candidates' Learning and Studying Strategies in the Context of Self-Regulation

    Science.gov (United States)

    Yilmaz, Özkan

    2017-01-01

    This study investigated the students' individual study and learning strategies. Toward this purpose, open ended question form was administered to 40 university students who have enrolled department of mathematics and science education, faculty of education. Students were selected randomly in all level of class. Qualitative research method was used…

  20. Evaluation of Reading Habits of Teacher Candidates: Study of Scale Development

    Science.gov (United States)

    Erkan, Senem Seda Sahenk; Dagal, Asude Balaban; Tezcan, Özlem

    2016-01-01

    The main purpose of this study was to develop a valid and reliable scale for printed and digital competencies ("The Printed and Digital Reading Habits Scale"). The problem statement of this research can be expressed as: "The Printed and Digital Reading Habits Scale: is a valid and reliable scale?" In this study, the scale…

  1. A genome-wide study of panic disorder suggests the amiloride-sensitive cation channel 1 as a candidate gene

    DEFF Research Database (Denmark)

    Gregersen, Noomi; Dahl, Hans A.; Buttenschön, Henriette N.

    2012-01-01

    Panic disorder (PD) is a mental disorder with recurrent panic attacks that occur spontaneously and are not associated to any particular object or situation. There is no consensus on what causes PD. However, it is recognized that PD is influenced by environmental factors, as well as genetic factors....... Despite a significant hereditary component, genetic studies have only been modestly successful in identifying genes of importance for the development of PD. In this study, we conducted a genome-wide scan using microsatellite markers and PD patients and control individuals from the isolated population...... of the Faroe Islands. Subsequently, we conducted a fine mapping, which revealed the amiloride-sensitive cation channel 1 (ACCN1) located on chromosome 17q11.2-q12 as a potential candidate gene for PD. The further analyses of the ACCN1 gene using single-nucleotide polymorphisms (SNPs) revealed significant...

  2. The Normality of EU Sport Policy Studies: Disciplinary Locus in Political Science, Sport Science or Elsewhere?

    Directory of Open Access Journals (Sweden)

    Jacob Kornbeck

    2014-05-01

    Full Text Available The Normality of EU Sport Policy Studies: Disciplinary Locus in Political Science, Sport Science or Elsewhere? Mainstream European integration research has shown that research on the EU tends to follow the conjunctures of European integration itself. This realisation has led to some debate on which branch of political science – international relations or government – or indeed other academic disciplines is/are the most appropriate locus for such research. The paper takes these debates one step further by looking at the occurrence of ‘EU & sport’ studies within the wider field of EU studies. The main material used comes from the ECLAS database. Findings lead to a discussion of whether ‘EU & sport’ studies should rather be for EU specialists or for sport specialists and a plea for disciplinary normalisation whereby sport science would need to get more directly involved (without necessarily overwriting political science. Some ideas are added regarding the need for a mapping of Central & Eastern European scholarship. Normalita politických studií EU v oblasti sportu: místo v oborech politologie, sportovních vědách či jinde? Hlavní integrační proudy v evropském výzkumu dokumentují, že výzkum v EU má tendenci zkoumat evropskou integraci jako takovou. Toto poznání vedlo k diskusi, v kterém oboru politologie – mezinárodní vztahy či vláda – nebo i v jiných akademických disciplínách je nejvhodnější místo pro takový výzkum. Stať se pokouší posunout tyto diskuse o krok dále tím, že studie o „EU a sportu“ se posuzují v širším záběru EU studií. Hlavní informační zdroje pocházejí z databáze ECLAS. Naše zjištění vedou k diskusi o problematice „EU a sportu“ v tom smyslu, zda by tyto studie měly být spíše určeny odborníkům EU, nebo sportovním specialistům. Důležitá je otázka disciplinární začlenění této problematiky, s širším zapojením sportovních věd (aniž by

  3. Do Political Attitudes Affect Consumer Choice? Evidence from a Large-Scale Field Study with Genetically Modified Bread in Switzerland

    Directory of Open Access Journals (Sweden)

    Philipp Aerni

    2011-09-01

    Full Text Available Independent of the left-right model of ideological structure, genetically modified organisms (GMOs in food and agriculture are resented across the political spectrum in Switzerland. In the absence of any real experience with genetically modified (GM food but faced with continuous exposure to warning messages in the media, conditioned feelings related to such a politically sensitive product may have a significant influence on revealed consumer choice. In our large-scale field study, we examined this assumption by selling three types of bread labeled as ‘made with organic corn’, ‘made with genetically modified corn’ and ‘made with conventional corn’ respectively in five locations across Switzerland using different price scenarios and selling groups. Customers who decided to buy bread also received an envelope containing a questionnaire about their prior political attitude expressed through their voting decision in a national referendum on a five-year ban on GMOs in 2005. The results demonstrate that consumer purchase decisions are determined by contextual factors not captured by general political attitudes. Surprisingly, the mere presence of GM food did have a positive impact on overall sales. The assumption that consumers would feel turned off by the mere presence of GM food for political reasons can therefore be safely discarded.

  4. The Logic of Political Media Scandals in Japan and the Case Study of Ozawa Ichirō

    Directory of Open Access Journals (Sweden)

    Igor Prusa

    2012-11-01

    Full Text Available First of all we wish to reveal certain universally-structuralist qualities, same as culturally-relative features of scandals and their mediation in a non-Western society. Secondly, we will illuminate how the mass media take active part in processing political issues in Japan, where as anywhere else in the media-saturated modern industrial world politicians significantly depend on the media (and vice versa; where political live shows and news programs – including scandals – became an important force, at times driving public sentiment while eventually generating support for opposition; and where wealth and its surplus is inevitably tied to a higher potential to grasp and secure power. We will then proceed to the main part of the paper, where we focus more closely on Japanese political scandals whereby preparing theoretical ground for a discourse analysis in the scandal case study of Ozawa Ichirō – one of the most powerful political heavyweights, and simultaneously one of the epitomes of political corruption in Japan.1 In our endeavor we were motivated by the fact that there exists plethora of literature on scandals in the west, but a detailed media discourse analysis of Japanese scandals is still lacking in academia worldwide.

  5. Texture, Textuality and Political Discourse: A Study of Lexical Cohesion in Nigeria's President Goodluck Jonathan's Inaugural Address, May, 2011

    Science.gov (United States)

    Enyi, Amaechi Uneke; Chitulu, Mark Ononiwu

    2015-01-01

    This study, entitled, "Texture and textuality in Political Discourse: A Study of Cohesive Devices in President Goodluck Jonathan's Inaugural Address-May, 2011" was an analysis of the lexical cohesive devices employed by Nigeria's President Goodluck Jonathan in crafting his May, 2011's Presidential Inaugural Address (PIA). Guided by the…

  6. An association study of suicide and candidate genes in the serotonergic system

    DEFF Research Database (Denmark)

    Buttenschon, H. N.; Flint, T. J.; Foldager, L.

    2013-01-01

    Introduction: Strong evidence demonstrates a genetic susceptibility to suicidal behaviour and a relationship between suicide and mental disorders. The aim of this study was to test for association between suicide and five selected genetic variants, which had shown association with suicide in other...... populations. Method: We performed a nationwide case-control study on all suicide cases sent for autopsy in Denmark between the years 2000 and 2007. The study comprised 572 cases and 1049 controls and is one of the largest genetic studies in completed suicide to date. The analysed markers were located within...... the Serotonin Transporter (SLC6A4), Monoamine Oxidase-A (MAOA) and the Ttyptophan Hydroxylase I and II (TPH1 and TPH2) genes. Results: None of the genetic markers within SLC6A4, MAOA, TPH1 and TPH2 were significantly associated with completed suicide or suicide method in the basic association tests. Exploratory...

  7. Politics, Security, Theory

    DEFF Research Database (Denmark)

    Wæver, Ole

    2011-01-01

    ’ is distinct from both the study of political practices of securitization and explorations of competing concepts of politics among security theories. It means tracking what kinds of analysis the theory can produce and whether such analysis systematically impacts real-life political struggles. Securitization...... theory is found to ‘act politically’ through three structural features that systematically shape the political effects of using the theory. The article further discusses – on the basis of the preceding articles in the special issue – three emerging debates around securitization theory: ethics...

  8. New Institutional Politics

    Directory of Open Access Journals (Sweden)

    Buğra KALKAN

    2015-12-01

    Full Text Available New institutional politics is an interdisciplinary movement that tries to reinstate the institutional politics to the center of the political science. After the limits of formal-legal analyze, used by old institutional politics, have been criticized by behaviorists, rational choice and neo-Marxist movements, since 1950, the state was alienated from the center of the political studies as an independent variable. Since 1980, neo institutional politics, raised as a reaction to this development, has been developing a new description and understanding of the institution which goes beyond the limitations of the old one. The rise and change of the political institutions and the interactions between political institutions and the actors, are being retheorized, by depending on informal rules and conventions as much as formal rules, and pointing out cultural factors as much as legal factors. So, in this study, rational choice, sociological and historical new institutional politics, as the three different school of new institutionalism, will be examined separately and there will be a debate on colliding and overlapping points of these schools

  9. Changes in gene expression linked with adult reproductive diapause in a northern malt fly species: a candidate gene microarray study

    Directory of Open Access Journals (Sweden)

    Hoikkala Anneli

    2010-02-01

    Full Text Available Abstract Background Insect diapause is an important biological process which involves many life-history parameters important for survival and reproductive fitness at both individual and population level. Drosophila montana, a species of D. virilis group, has a profound photoperiodic reproductive diapause that enables the adult flies to survive through the harsh winter conditions of high latitudes and altitudes. We created a custom-made microarray for D. montana with 101 genes known to affect traits important in diapause, photoperiodism, reproductive behaviour, circadian clock and stress tolerance in model Drosophila species. This array gave us a chance to filter out genes showing expression changes during photoperiodic reproductive diapause in a species adapted to live in northern latitudes with high seasonal changes in environmental conditions. Results Comparisons among diapausing, reproducing and young D. montana females revealed expression changes in 24 genes on microarray; for example in comparison between diapausing and reproducing females one gene (Drosophila cold acclimation gene, Dca showed up-regulation and 15 genes showed down-regulation in diapausing females. Down-regulation of seven of these genes was specific to diapause state while in five genes the expression changes were linked with the age of the females rather than with their reproductive status. Also, qRT-PCR experiments confirmed couch potato (cpo gene to be involved in diapause of D. montana. Conclusions A candidate gene microarray proved to offer a practical and cost-effective way to trace genes that are likely to play an important role in photoperiodic reproductive diapause and further in adaptation to seasonally varying environmental conditions. The present study revealed two genes, Dca and cpo, whose role in photoperiodic diapause in D. montana is worth of studying in more details. Also, further studies using the candidate gene microarray with more specific experimental

  10. Obesity and treatment meanings in bariatric surgery candidates : a qualitative study

    OpenAIRE

    Silva, Susana Sofia P.; Maia, Ângela

    2012-01-01

    Background This study used a qualitative approach to comprehend how the morbid obese conceptualize and deal with obesity and obesity treatment, with the particular aim of exploring the expectations and beliefs about the exigencies and the impact of bariatric surgery. Methods The study population included 30 morbid obese patients (20 women and 10 men) with a mean age of 39.17 years (SD = 8.81) and a mean body mass index of 47.5 (SD = 8.2) interviewed individually before surgery using ...

  11. Study of thermal stability and degradation of fire resistant candidate polymers for aircraft interiors

    Science.gov (United States)

    Hsu, M. T. S.

    1976-01-01

    The thermochemistry of bismaleimide resins and phenolphthalein polycarbonate was studied. Both materials are fire-resistant polymers and may be suitable for aircraft interiors. The chemical composition of the polymers has been determined by nuclear magnetic resonance and infrared spectroscopy and by elemental analysis. Thermal properties of these polymers have been characterized by thermogravimetric analyses. Qualitative evaluation of the volatile products formed in pyrolysis under oxidative and non-oxidative conditions has been made using infrared spectrometry. The residues after pyrolysis were analyzed by elemental analysis. The thermal stability of composite panel and thermoplastic materials for aircraft interiors was studied by thermogravimetric analyses.

  12. A genome-wide association study on androstenone levels in pigs reveals a cluster of candidate genes on chromosome 6

    Directory of Open Access Journals (Sweden)

    Groenen Martien AM

    2010-05-01

    Full Text Available Abstract Background In many countries, male piglets are castrated shortly after birth because a proportion of un-castrated male pigs produce meat with an unpleasant flavour and odour. Main compounds of boar taint are androstenone and skatole. The aim of this high-density genome-wide association study was to identify single nucleotide polymorphisms (SNPs associated with androstenone levels in a commercial sire line of pigs. The identification of major genetic effects causing boar taint would accelerate the reduction of boar taint through breeding to finally eliminate the need for castration. Results The Illumina Porcine 60K+SNP Beadchip was genotyped on 987 pigs divergent for androstenone concentration from a commercial Duroc-based sire line. The association analysis with 47,897 SNPs revealed that androstenone levels in fat tissue were significantly affected by 37 SNPs on pig chromosomes SSC1 and SSC6. Among them, the 5 most significant SNPs explained together 13.7% of the genetic variance in androstenone. On SSC6, a larger region of 10 Mb was shown to be associated with androstenone covering several candidate genes potentially involved in the synthesis and metabolism of androgens. Besides known candidate genes, such as cytochrome P450 A19 (CYP2A19, sulfotransferases SULT2A1, and SULT2B1, also new members of the cytochrome P450 CYP2 gene subfamilies and of the hydroxysteroid-dehydrogenases (HSD17B14 were found. In addition, the gene encoding the ß-chain of the luteinizing hormone (LHB which induces steroid synthesis in the Leydig cells of the testis at onset of puberty maps to this area on SSC6. Interestingly, the gene encoding the α-chain of LH is also located in one of the highly significant areas on SSC1. Conclusions This study reveals several areas of the genome at high resolution responsible for variation of androstenone levels in intact boars. Major genetic factors on SSC1 and SSC6 showing moderate to large effects on androstenone

  13. Political CSR

    DEFF Research Database (Denmark)

    Jeppesen, Søren; Morsing, Mette

    We engage a discussion of political CSR in SMEs in an African context. Based on critical observations on Western MNC CSR action in emerging economies that holds counterproductive implications for social development, political economists have argued that business profit far more than society...... development in local African communities. Our findings extend political CSR research by directing attention to how the corporate influence in developing economies does not only emerge from MNCs but is also established and retained by SMEs CSR work....

  14. Political Competitiveness

    OpenAIRE

    Casey B. Mulligan; Kevin K. Tsui

    2006-01-01

    Political competitiveness - which many interpret as the degree of democracy - can be modeled as a monopolistic competition. All regimes are constrained by the threat of "entry," and thereby seek some combination of popular support and political entry barriers. This simple model predicts that many public policies are unrelated to political competitiveness, and that even unchallenged nondemocratic regimes should tax far short of their Laffer curve maximum. Economic sanctions, odious debt repudi...

  15. Political Ecology

    OpenAIRE

    DeFriez, Joshua; Larsen, Justine; Hilton, Nicholas

    2014-01-01

    Environmental legislation is commonly accepted as an altruistic approach to land management. A closer examination however, reveals that political incentives and flawed arguments consistently shape U.S. environmental policy at high public costs. As student fellows at the Institute of Political Economy at Utah State University, we have had the opportunity to research this subject under the direction of Professor Randy Simmons. Political Ecology is his upcoming book that explores a variety of en...

  16. Political administration

    OpenAIRE

    Åkerstrøm Andersen, Niels

    2000-01-01

    One of the major discussions of the 1990s has been about the relation between politics and administration. The themes of the discussions have been many and varied. It has been suggested that the level of politics should concentrate on the general political outlining and entrust the remaining to the administration. It has been criticised that politicians make their decisions on the basis of single cases, which ought to be an administrative matter entirely. It has been a theme that efficient op...

  17. Transcriptomic and genetic studies identify NFAT5 as a candidate gene for cocaine dependence

    NARCIS (Netherlands)

    Fernandez-Castillo, N.; Cabana-Dominguez, J.; Soriano, J.; Sanchez-Mora, C.; Roncero, C.; Grau-Lopez, L.; Ros-Cucurull, E.; Daigre, C.; Donkelaar, M.M.J. van; Franke, B.; Casas, M.; Ribases, M.; Cormand, B.

    2015-01-01

    Cocaine reward and reinforcing effects are mediated mainly by dopaminergic neurotransmission. In this study, we aimed at evaluating gene expression changes induced by acute cocaine exposure on SH-SY5Y-differentiated cells, which have been widely used as a dopaminergic neuronal model. Expression

  18. Influence of Candidate Genes on Attention Problems in Children: A Longitudinal Study

    NARCIS (Netherlands)

    van Beijsterveldt, C.E.M.; Middeldorp, C.M.; Slof-Op 't Landt, M.C.T.; Bartels, M.; Hottenga, J.J.; Suchiman, H.E.D.; Slagboom, P.E.; Boomsma, D.I.

    2011-01-01

    Attention problems form one of the core characteristics of Attention-Deficit Hyperactive Disorder (ADHD), a multifactorial neurodevelopmental disorder. From twin research it is clear that genes play a considerable role in the etiology and in the stability of ADHD in childhood. Association studies

  19. Genetic Influence of Candidate Osteoporosis Genes in Saudi Arabian Population: A Pilot Study

    Directory of Open Access Journals (Sweden)

    Mir Sadat-Ali

    2012-01-01

    Full Text Available Background and Objectives. The purpose of the present study is to find the genes and SNP that influence BMD and postmenopausal Saudi women. Material and Methods. Two-hundred ethnic Saudi Arabian women with a diagnosis of postmenopausal osteoporosis were the subjects of this study. Baseline blood hematology, biochemistry, and bone panel were done. Blood was collected, and three TaqMan-MGB probes were used to analyze SNP variants in ALOX15 (rs7220870, LRP5 (C 25752205 10, and TNFRSF11B (C 11869235 10. Results. The variant of ALOX15 17p13 showed that the BMD of the spine was lower in the AA allele (P value <0.002 and fractures were highest at 50% compared to CC allele. In the TNFRSF11B gene, BMD of the hip and spine was significantly higher in the GG allele and the history of fractures was significantly higher in GG group. With regard to the LRP5 (C 25752205 10 gene, there was no significant difference between allele groups. Conclusion(s. This study shows that the genetic influence of osteoporosis in the Caucasian and Saudi Arabians population is similar. We believe that the same genetic markers that influence osteoporosis in the Caucasian race could be used for further studies in the Saudi Arabian population.

  20. Genetic influence of candidate osteoporosis genes in saudi arabian population: a pilot study.

    Science.gov (United States)

    Sadat-Ali, Mir; Al-Turki, Haifa A

    2012-01-01

    Background and Objectives. The purpose of the present study is to find the genes and SNP that influence BMD and postmenopausal Saudi women. Material and Methods. Two-hundred ethnic Saudi Arabian women with a diagnosis of postmenopausal osteoporosis were the subjects of this study. Baseline blood hematology, biochemistry, and bone panel were done. Blood was collected, and three TaqMan-MGB probes were used to analyze SNP variants in ALOX15 (rs7220870), LRP5 (C 25752205 10), and TNFRSF11B (C 11869235 10). Results. The variant of ALOX15 17p13 showed that the BMD of the spine was lower in the AA allele (P value LRP5 (C 25752205 10) gene, there was no significant difference between allele groups. Conclusion(s). This study shows that the genetic influence of osteoporosis in the Caucasian and Saudi Arabians population is similar. We believe that the same genetic markers that influence osteoporosis in the Caucasian race could be used for further studies in the Saudi Arabian population.

  1. Association studies of serotonin system candidate genes in early-onset obsessive-compulsive disorder.

    Science.gov (United States)

    Dickel, Diane E; Veenstra-VanderWeele, Jeremy; Bivens, Nancy Chiu; Wu, Xiaolin; Fischer, Daniel J; Van Etten-Lee, Michelle; Himle, Joseph A; Leventhal, Bennett L; Cook, Edwin H; Hanna, Gregory L

    2007-02-01

    Family-based evidence for association at serotonin system genes SLC6A4, HTR1B, HTR2A, and brain-derived neurotrophic factor (BDNF) has been previously reported in obsessive-compulsive disorder (OCD). Early-onset OCD is a more familial form of the disorder. We used the transmission-disequilibrium test of association at common polymorphisms in each of these genes in 54 parent-child trios ascertained through probands with early-onset OCD. No evidence for association was detected at any of the polymorphisms in the entire set of subjects. Nominally significant association was found at the HTR2A rs6311 polymorphism in subjects with tic disorder and OCD (p = .05), replicating a previous finding in Tourette syndrome and OCD. Nominally significant association was also found for the SLC6A4 HT transporter gene-linked polymorphic region (5-HTTLPR) polymorphism for female subjects (p = .03). Neither association would remain significant after statistical correction for multiple testing. Despite no individual study reporting replication, a pooled analysis of five replication studies of the SLC6A4 5-HTTLPR polymorphism supports association (p = .02). Low power across individual association studies in OCD may lead to a false acceptance of the null hypothesis. Accumulation of evidence from multiple studies will be necessary to evaluate the potential role for these genes in contributing to susceptibility to OCD.

  2. Variable selection in Bayesian generalized linear-mixed models: an illustration using candidate gene case-control association studies.

    Science.gov (United States)

    Tsai, Miao-Yu

    2015-03-01

    The problem of variable selection in the generalized linear-mixed models (GLMMs) is pervasive in statistical practice. For the purpose of variable selection, many methodologies for determining the best subset of explanatory variables currently exist according to the model complexity and differences between applications. In this paper, we develop a "higher posterior probability model with bootstrap" (HPMB) approach to select explanatory variables without fitting all possible GLMMs involving a small or moderate number of explanatory variables. Furthermore, to save computational load, we propose an efficient approximation approach with Laplace's method and Taylor's expansion to approximate intractable integrals in GLMMs. Simulation studies and an application of HapMap data provide evidence that this selection approach is computationally feasible and reliable for exploring true candidate genes and gene-gene associations, after adjusting for complex structures among clusters. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  3. Political Terrorism in Southeast Asia and US Policy Issues: Case Studies of Thailand and Indonesia

    National Research Council Canada - National Science Library

    McDonald, George

    1998-01-01

    ... and regional Southeast Asian relations. The main purpose of this thesis is to examine political terrorism in Southeast Asia, with particular attention paid to terrorism conducted by separatist groups in Thailand and Indonesia...

  4. Candidate salivary biomarkers associated with alveolar bone loss: cross-sectional and in vitro studies

    OpenAIRE

    Ng, Patricia Yen Bee; Donley, Maureen; Hausmann, Ernest; Hutson, Alan D.; Rossomando, Edward F.; Scannapieco, Frank A.

    2007-01-01

    This cross-sectional study evaluated the association between radiographic evidence of alveolar bone loss and the concentration of host-derived bone resorptive factors (interleukin-1 beta, tumor necrosis factor-alpha, interleukin-6, prostaglandin-E2), and markers of bone turnover [pyridinoline cross-linked carboxyterminal telopeptide of type I collagen (ICTP), osteocalcin, osteonectin] in stimulated human whole saliva collected from 110 untreated dental patients. Alveolar bone loss scores for ...

  5. A candidate gene association study on muscat flavor in grapevine (Vitis vinifera L.

    Directory of Open Access Journals (Sweden)

    Boursiquot Jean-Michel

    2010-11-01

    Full Text Available Abstract Background The sweet, floral flavor typical of Muscat varieties (Muscats, due to high levels of monoterpenoids (geraniol, linalool and nerol, is highly distinct and has been greatly appreciated both in table grapes and in wine since ancient times. Muscat flavor determination in grape (Vitis vinifera L. has up to now been studied by evaluating monoterpenoid levels through QTL analysis. These studies have revealed co-localization of 1-deoxy-D-xylulose 5-phosphate synthase (VvDXS with the major QTL positioned on chromosome 5. Results We resequenced VvDXS in an ad hoc association population of 148 grape varieties, which included muscat-flavored, aromatic and neutral accessions as well as muscat-like aromatic mutants and non-aromatic offsprings of Muscats. Gene nucleotide diversity and intragenic linkage disequilibrium (LD were evaluated. Structured association analysis revealed three SNPs in moderate LD to be significantly associated with muscat-flavored varieties. We identified a putative causal SNP responsible for a predicted non-neutral substitution and we discuss its possible implications for flavor metabolism. Network analysis revealed a major star-shaped cluster of reconstructed haplotypes unique to muscat-flavored varieties. Moreover, muscat-like aromatic mutants displayed unique non-synonymous mutations near the mutated site of Muscat genotypes. Conclusions This study is a crucial step forward in understanding the genetic regulation of muscat flavor in grapevine and it also sheds light on the domestication history of Muscats. VvDXS appears to be a possible human-selected locus in grapevine domestication and post-domestication. The putative causal SNP identified in Muscat varieties as well as the unique mutations identifying the muscat-like aromatic mutants under study may be immediately applied in marker-assisted breeding programs aimed at enhancing fragrance and aroma complexity respectively in table grape and wine cultivars.

  6. Comparative study of therapeutic antibody candidates derived from mini-pool and clonal cell lines.

    Science.gov (United States)

    Fan, Lianchun; Rizzi, Giovanni; Bierilo, Kathleen; Tian, Jun; Yee, Joon Chong; Russell, Reb; Das, Tapan K

    2017-11-01

    The long journey of developing a drug from initial discovery target identification to regulatory approval often leaves many patients with missed window of opportunities. Both regulatory agencies and biopharmaceutical industry continue to develop creative approaches to shorten the time of new drug development in order to deliver life-saving medicine to patients. Generally, drug substance materials to support the toxicology and early phase clinical study can only be manufactured after creating the final Master Cell Bank (MCB) of the clonally derived cell line, which normally takes 1-2 years. With recent advances in cell line development, cell culture process and analytical technologies, generating more homogeneous bulk/mini-pool population with higher productivity and acceptable quality attributes has become a norm, thereby making it possible to shorten the timeline to initiate First in Human (FIH) trial by using bulk/mini-pool generated materials to support toxicology and FIH studies. In this study, two monoclonal antibodies of different subclasses (IgG1 and IgG4) were expressed from the mini-pool cells as well as clonally derived cell lines generated from the same mini-pool. Cell growth, productivity, and product quality were compared between the materials generated from the mini-pool and clonally derived cell line. The results demonstrate the similarity of the antibody products generated from mini-pool cells and clonally derived cell lines from the same mini-pool, and strongly support the concept and feasibility of using antibody materials produced from mini-pool cultures for toxicology and FIH studies. The strategy to potentially shorten the FIH timeline is discussed. © 2017 American Institute of Chemical Engineers Biotechnol. Prog., 33:1456-1462, 2017. © 2017 American Institute of Chemical Engineers.

  7. Political communication in Malaysia: a study on the use of new media

    OpenAIRE

    Leong, Pauline Pooi Yin

    2017-01-01

    To gain and retain political power, politicians utilise the mass media to persuade the polity to support them, especially during elections. The Barisan Nasional (BN) coalition has successfully manipulated the mass media in Malaysia to maintain power for the past 57 years, making it one of the longest serving government in the world. The emergence of new media, however, has challenged this status quo. The purpose of this thesis was to investigate how new media has influenced the political proc...

  8. Genomewide association analysis followed by a replication study implicates a novel candidate gene for neuroticism.

    Science.gov (United States)

    van den Oord, Edwin J C G; Kuo, Po-Hsiu; Hartmann, Annette M; Webb, B Todd; Möller, Hans-Jürgen; Hettema, John M; Giegling, Ina; Bukszár, József; Rujescu, Dan

    2008-09-01

    Neuroticism is a trait that reflects a tendency toward negative mood states. It has long been linked to internalizing psychiatric conditions, such as anxiety and depression, and it accounts for much of the substantial comorbidity seen between these disorders. To identify common genetic variants that affect neuroticism to better understand (the comorbidity between) a broad range of psychiatric disorders and to develop effective treatments. More than 420,000 genetic markers were tested for their association with neuroticism in a genomewide association study (GWAS). The GWAS sample consisted of 1227 healthy individuals ascertained from a US national sampling frame and available from the National Institute of Mental Health genetics repository. The most promising markers were subsequently tested in a German replication sample comprising 1880 healthy individuals. A strict definition of replication (same marker, same direction of effects, and same measure) combined with a threshold we proposed previously for declaring significance in genetic studies that ensures a mean probability of producing false-positive findings of less than 10%. The most promising results in the GWAS and replication samples were single-nucleotide polymorphisms (SNPs) in the gene MAMDC1. These SNPs all tagged the same 2 haplotypes and had P values of 10(-5) to 10(-6) in the GWAS sample and of .006 to .02 in the replication sample. Furthermore, the replication involved the same SNPs and the same direction of effects. In a combined analysis of all data, several SNPs were significant according to the threshold that allows for 10% false-positive findings. The small effect sizes may limit the prognostic, diagnostic, and therapeutic use of SNP markers such as those in MAMDC1. However, the present study demonstrates the potential of a GWAS to discover potentially important pathogenic pathways for which clinically more powerful (bio)markers may eventually be developed.

  9. Political Preferences and Individual Choice: A Latin American's Countries Perspective

    Directory of Open Access Journals (Sweden)

    Regina Carla Madalozzo

    American countries, a significant amount of future research remains. The definitions of “left” and “right” continue to be unclear as they relate to dimensions that include democracy, autocracy, and political reform. Understanding the ways individuals set up their choices would increase the responsibility of political parties and authorities for the hidden claim the population has about their deliverables. At the same time, studies like ours may enhance the awareness of the general impression over political party choices of candidates. Finally, even with so many confounding aspects in this antagonist position, the left and the right continue to be a simple way to characterize veiled assumptions. Therefore, it may be an ambiguous form of defining choices, but this seemingly binary choice is still very significant for voters in Latin America.

  10. Transcriptome and Proteome Studies Reveal Candidate Attachment Genes during the Development of the Barnacle Amphibalanus Amphitrite

    KAUST Repository

    Al-Aqeel, Sarah

    2016-09-21

    The acorn barnacle, Balanus amphitrite, is the main biofouling organism in marine environments. In the present study we profiled the transcriptome and proteome of B. amphitrite at different life stages (nauplius II, nauplius VI, and cyprid) from the Red Sea, where the average water surface temperature is 34°C and the salinity reaches 41%. We identified 65,784 expressed contigs, and a total of 1387 expressed proteins measured by quantitative proteomics. We found that osmotic stress, salt stress, hyperosmotic response and the Wnt signaling pathway were strongly up-regulated during the planktonic stage, while the MAPK pathway, lipid metabolism, and cuticle development genes were down-regulated. In the transition stage between the nauplius VI and the cyprid, genes that are involved in blood coagulation, cuticle development and eggshell formation were highly up-regulated, while the nitric oxide pathway, which stimulates the swimming and feeding response in marine invertebrates, was down-regulated. We are able to report for the first time that sound sensory system proteins are highly abundant in the nauplius VI stage, implying that these proteins are good targets for the development of new antifouling compounds. The results presented here together with the new genome-wide datasets for a non-model specie represent an important resource for the study of biofouling and development. Proteomics data are available via ProteomeXchange with identifier PXD004679.

  11. Transcriptome and proteome studies reveal candidate attachment genes during the development of the barnacle Amphibalanus Amphitrite

    Directory of Open Access Journals (Sweden)

    Sarah Al-Aqeel

    2016-09-01

    Full Text Available The acorn barnacle, Balanus amphitrite, is the main biofouling organism in marine environments. In the present study we profiled the transcriptome and proteome of B. amphitrite at different life stages (nauplius II, nauplius VI and cyprid from the Red Sea, where the average water surface temperature is 34°C and the salinity reaches 41‰. We identified 65,784 expressed contigs, and a total of 1,387 expressed proteins measured by quantitative proteomics. We found that osmotic stress, salt stress, hyperosmotic response and the Wnt signaling pathway were strongly up-regulated during the planktonic stage, while the MAPK pathway, lipid metabolism, and cuticle development genes were down-regulated. In the transition stage between the nauplius VI and the cyprid, genes that are involved in blood coagulation, cuticle development and eggshell formation were highly up-regulated, while the nitric oxide pathway, which stimulates the swimming and feeding response in marine invertebrates, was down-regulated. We are able to report for the first time that sound sensory system proteins are highly abundant in the nauplius VI stage, implying that these proteins are good targets for the development of new antifouling compounds. The results presented here together with the new genome-wide datasets for a non-model specie represent an important resource for the study of biofouling and development.

  12. Art therapy and mindfulness with survivors of political violence: A qualitative study.

    Science.gov (United States)

    Kalmanowitz, Debra L; Ho, Rainbow T H

    2017-08-01

    This study's objective was to understand how art therapy and mindfulness meditation could be integrated together in the context of different cultures and political violence and in work with asylum seekers suffering from trauma. We conducted a qualitative phenomenological study based on the social construction paradigm. Twelve participants took part in 4 intensive full-day art therapy and mindfulness workshops. The study's setting was an art therapy and mindfulness studio ( Inhabited Studio ) in Hong Kong where participants engaged in art making and in mindfulness-meditation practice. Different aspects of the Inhabited Studio appealed to participants based on each individual's worldview, culture, religion, and coping style. Responses to the Inhabited Studio were organized into 7 thematic clusters. Five themes were categorized into 2 broad categories composed of personal elements (memory, identity) and mediating aspects (emotional/self-regulation, communication, and imagination). The final 2, resilience and worldview, spanned both areas. Participants found the Inhabited Studio culturally compatible and some of the skills they learned helpful in times of stress. This points to how this combination can contribute to building resilience. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  13. Homogeneity study on biological candidate reference materials: the role of neutron activation analysis

    International Nuclear Information System (INIS)

    Silva, Daniel P.; Moreira, Edson G.

    2015-01-01

    Instrumental Neutron activation Analysis (INAA) is a mature nuclear analytical technique able to accurately determine chemical elements without the need of sample digestion and, hence, without the associated problems of analyte loss or contamination. This feature, along with its potentiality use as a primary method of analysis, makes it an important tool for the characterization of new references materials and in the assessment of their homogeneity status. In this study, the ability of the comparative method of INAA for the within-bottle homogeneity of K, Mg, Mn and V in a mussel reference material was investigated. Method parameters, such as irradiation time, sample decay time and distance from sample to the detector were varied in order to allow element determination in subsamples of different sample masses in duplicate. Sample masses were in the range of 1 to 250 mg and the limitations of the detection limit for small sample masses and dead time distortions for large sample masses were investigated. (author)

  14. Homogeneity study on biological candidate reference materials: the role of neutron activation analysis

    Energy Technology Data Exchange (ETDEWEB)

    Silva, Daniel P.; Moreira, Edson G., E-mail: dsilva.pereira@usp.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2015-07-01

    Instrumental Neutron activation Analysis (INAA) is a mature nuclear analytical technique able to accurately determine chemical elements without the need of sample digestion and, hence, without the associated problems of analyte loss or contamination. This feature, along with its potentiality use as a primary method of analysis, makes it an important tool for the characterization of new references materials and in the assessment of their homogeneity status. In this study, the ability of the comparative method of INAA for the within-bottle homogeneity of K, Mg, Mn and V in a mussel reference material was investigated. Method parameters, such as irradiation time, sample decay time and distance from sample to the detector were varied in order to allow element determination in subsamples of different sample masses in duplicate. Sample masses were in the range of 1 to 250 mg and the limitations of the detection limit for small sample masses and dead time distortions for large sample masses were investigated. (author)

  15. An ultrastructural and a cytochemical study of candidal invasion of reconstituted human oral epithelium.

    Science.gov (United States)

    Jayatilake, J A M S; Samaranayake, Y H; Samaranayake, L P

    2005-04-01

    Opportunistic yeast, Candida albicans causes superficial and systemic mycoses in compromised patients. Adhesion to host tissues, morphogenesis and extracellular phospholipases (PL) are thought to contribute to its virulence. The nature of numerous host-parasite interactions at the invasive phase of oral candidiasis is not fully understood. Hence in this study, we explore the ultrastructural features of oral candidiasis using a tissue culture model based on reconstituted human oral epithelium (RHOE). Reconstituted human oral epithelium (Skinethic Laboratory, Nice, France) was inoculated with C. albicans SC5314 and incubated up to 48 h. The infected tissue was harvested at 12, 24 and 48 h and examined using light, scanning (SEM) and transmission electron microscopy (TEM). Localized activity of PLs of C. albicans during tissue invasion was also examined using a cytochemical method. Over a period of 48 h C. albicans invaded the RHOE, and histological examination revealed characteristic hallmarks of pathological tissue invasion. Hyphal penetration into the superficial epithelium, particularly at cell junctions, together with features of cellular internalization of yeasts was noted. Phospholipase activity was visible at the tips of hyphae and initial sites of bud formation. Further, SEM studies revealed cavitations on the surface epithelial cells particularly pronounced at the sites of hyphal invasion. Hyphal invasion was seen both at cell surfaces and intercellular cell junctions of the epithelium, the latter resembling thigmotropic behaviour. Our findings confirm that multiple cellular interactions such as internalization, thigmotropism and extracellular PLs contribute to invasive candidiasis. The RHOE model, described here, appears to be a satisfactory model for the investigation of ultrastructural and histochemical features of invasive candidiasis in humans.

  16. Political Parties and Interest Groups Members' Patterns of Social Network Site Usage in Kyrgyzstan

    Directory of Open Access Journals (Sweden)

    Elira Turdubaeva

    2014-11-01

    Full Text Available Kyrgyzstan, with a high level of political participation and an avant-garde position regarding internet access in Central Asia, broadband and social media penetration in the population, is a critical case for studying social network sites (SNSs in relation to political participation. This study analyzes the practices and attitudes of SNS users in Kyrgyzstan. Two types of users – members of political parties and members of interest organizations – are interviewed in focus groups about their practices and attitudes towards political content in the social network site Facebook. The findings indicate that, to some extent, the political engagement is indeed occurring within the Facebook environment, suggesting that the popular social networking sites (SNSs are an avenue for young people to express and share their political views. Facebook allowed users to share their political beliefs, support specific candidates, and interact with others on political issues. Participants’ perceptions regarding the appropriateness of political activity on Facebook, as well as the specific types of political activities they engaged in and witnessed within the site, were also explored.

  17. Stress-corrosion-cracking studies on candidate container alloys for the Tuff Repository

    International Nuclear Information System (INIS)

    Beavers, J.A.; Durr, C.L.

    1992-05-01

    Cortest Columbus Technologies, Inc. (CC Technologies) investigated the long-term performance of container materials used for high-level waste package as part of the information needed by the Nuclear Regulatory Commission (NRC) to assess the Department of Energy's application to construct to geologic repository for high-level radioactive waste. At the direction of the NRC, the program focused on the Tuff Repository. This report summarizes the results of Stress-Corrosion-Cracking (SCC) studies performed in Tasks 3, 5, and 7 of the program. Two test techniques were used; U-bend exposures and Slow-Strain-Rate (SSR) tests. The testing was performed on two copper-base alloys (Alloy CDA 102 and Alloy CDA 175) and two Fe-Cr-Ni alloys (Alloy 304L and Alloy 825) in simulated J-13 groundwater and other simulated solutions for the Tuff Repository. These solutions were designed to simulate the effects of concentration and irradiation on the groundwater composition. All SCC testing on the Fe-Cr-Ni Alloys was performed on solution-annealed specimens and thus issues such as the effect of sensitization on SCC were not addressed

  18. Analytical Study of Self-Motivations among a Southwest Public University Nonpolitical Science Major Students in Required Political Science Courses

    Science.gov (United States)

    Gasim, Gamal; Stevens, Tara; Zebidi, Amira

    2012-01-01

    All undergraduate students are required by state law to take six credited hours in political science. This study will help us identify if differences exist in self-determination among students enrolled in American Public Policy and American Government at a large, Southwestern public university. Because some types of motivation are associated with…

  19. Hegemony and the Politics of Policy Making for Education for Sustainable Development: A Case Study of Vietnam

    Science.gov (United States)

    Bengtsson, Stefan Lars

    2016-01-01

    Assumptions are readily made about the global nature and discourse of education for sustainable development. This study challenges assumptions made about structural power as expressed through Education for Sustainable Development (ESD) policy and politics of education. Focusing on the concept of sustainable development (SD) and ESD, the research…

  20. Principals' Perceptions of Politics

    Science.gov (United States)

    Tooms, Autumn K.; Kretovics, Mark A.; Smialek, Charles A.

    2007-01-01

    This study is an effort to examine principals' perceptions of workplace politics and its influence on their productivity and efficacy. A survey was used to explore the perceptions of current school administrators with regard to workplace politics. The instrument was disseminated to principals serving public schools in one Midwestern state in the…

  1. Enhancing Political Participation in Jamaica

    Directory of Open Access Journals (Sweden)

    Lloyd George Waller

    2013-04-01

    Full Text Available Youth participation through political talk appears to be shifting to the online public sphere in many parts of the world. Many attribute this shift to online social networks such as Facebook. Emerging research seem to suggest that this may be a cure for the problem of political apathy among the youth. This study explores such a possibility in Jamaica. In all, 752 youth ages 15 to 24 were surveyed to ascertain whether Facebook encourages political talk among this age cohort, and what if any are the primary factors that discourage this practice. The findings suggest that (a Facebook is an extension of offline political talk among the civically engaged and politically charged youth of Jamaica; (b Facebook does not substantively encourage political talk among the politically apathetic Jamaican youth; and (c fear of political victimization is the primary factor that discourages many Jamaican youth to engage in political talk on Facebook.

  2. Do inferences of competence from faces predict political selection in authoritarian regimes? Evidence from China.

    Science.gov (United States)

    Wong, Stan Hok-Wui; Zeng, Yu

    2017-08-01

    Candidate appearance is a significant predictor of election outcomes in democracies because voters often make inference of competence based on facial appearance. Do inferences of competence from faces matter in autocracies? In this article, we study the effects of candidate appearance on the selection of three types of Chinese officials: (1) rural deputies elected to a local people's congress (LPC), (2) urban deputies elected to the LPC, and (3) unelected mayors and bureaucrats. We find that facial competence cues are relevant only to the votes received by rural LPC candidates. Our findings suggest the importance of information accessibility in political selection. In particular, the "selectorate" of mayors and bureaucrats do not need facial appearance cues because they have access to substantive information about the quality of political candidates. Our findings provide a possible explanation for the resilience of some autocracies: they are able to identify talent through an informative, albeit non-electoral, selection mechanism. Copyright © 2016 Elsevier Inc. All rights reserved.

  3. Environmental knowledge, environmental politics. Case studies from Canada and Western Europe

    International Nuclear Information System (INIS)

    Clapperton, Jonathan; Piper, Liza

    2016-01-01

    The ways in which we come to know the environment are always inherently political - as are the ways in which environmental knowledge is put to use in the world. Focusing on ''scientific knowledge'' and ''Indigenous knowledge,'' on knowledge obtained through work as well as through leisure, the contributions in this volume explore how environmental knowledge is acquired, constructed, and deployed to make political claims on or for the environment. This volume also shows how environmental knowledge is embedded in grassroots, national, and international political efforts to find solutions to environmental problems. These essays showcase examples from Canada and Western Europe, offering insights into how different forms of environmental knowledge and environmental politics come to be seen as legitimate or illegitimate. This volume contains nine topics: 1. Indigenous Ecological Knowledge and the Politics of Postcolonial Writing (Jonathan Clapperton); 2. Bitumen Exploration and the Southern Re-Inscription of Northeastern Alberta: 1875-1967 (Hereward Longley); 3. Pollution, Local Activism, and the Politics of Development in the Canadian North (John Sandlos and Arn Keeling); 4. Seeds of Knowledge: From Back-to-the-Land to Urban Gardening (Nancy Janovicek); 5. Between Stewardship and Exploitation: Private Tourism, State Parks, and Environmentalism (Jessica M. DeWitt); 6. Reflections on Water: Knowing a River (Marianna Dudley); 7. ''We Are as Gods'': The Green Technical Fix (Henry Trim); 8. Environmental Knowledge and Politics in Portugal: From Resistance to Incorporation (Margarida Queiros); 9. Coal in the Age of the Oil Sands (Liza Piper).

  4. Regional Autonomy and Local Democracy: Independent Candidates Cases

    Directory of Open Access Journals (Sweden)

    Suryanto

    2016-11-01

    Full Text Available One of the efforts to achieve local democracy is through the participation of independent candidates in the Direct General Election in the region. The presence of independent candidates in the Direct General Election gives a great hope to change the political structure of the shackles of the old forces. This paper aims to discuss the implication of regional heads coming from independent candidates on the effectiveness of local governance and the implementation of substantive democracy in the region. The method used is a qualitative approach using descriptive research method. The data collection is done through literature approach. Processing data uses Milles and Huberman interactive models, which includes data reduction, data presentation, and conclusion. The study concluded three things: First, the presence of independent candidates in the Direct General Election gives the opportunities to achieve local democracy that is getting bigger, Second, Regional Heads elected from independent candidates face the challenges of the ineffectiveness of regional government, and Third, within certain limits, the power of elected regional heads from independent lane leads to the realization of democracy that is not substantial.

  5. Media Competition and Electoral Politics

    NARCIS (Netherlands)

    Piolatto, A.; Schuett, F.

    2013-01-01

    Abstract: We build a framework linking competition in the media market to political participation, media slant, and selection of politicians. Media outlets report on the ability of candidates running for office and compete for audience through their choice of slant. Citizens derive utility from

  6. The (limited) political influence of ecological economics. A case study on Dutch environmental policies

    International Nuclear Information System (INIS)

    Boezeman, Daan; Leroy, Pieter; Maas, Rob; Kruitwagen, Sonja

    2010-01-01

    Although the ecological economics (EE) discourse attempts to influence environmental policy, empirical studies have concluded that its success in this endeavour has been limited thus far. In the Netherlands, however, two EE-related policy concepts, Environmental Utilisation Space and Ecological Footprint, were strongly present in environmental policy during certain periods in time, but subsequently disappeared from the environmental agenda. The central question of this article is how these ups and downs of the EE concepts can be understood: which factors determine their rise on and fall from the policy agenda over time? To answer this question, this article offers a conceptual model informed by the approaches in political science on framing, agenda-setting and knowledge utilisation. We conclude that the interplay of concept-specific characteristics, the formation of coalitions around the concept and contextual variables explain the rise and fall of the aforementioned concepts. A match between the dominant policy frame and the core elements of the concept provides the opportunity for the two concepts to be pushed on the agenda. We observe the alternation of 'constraining' frames, which allows for EE concepts to survive, and 'reconciling' frames, which block agenda entrance for EE concepts. Furthermore, the alternation of these frames seems to correlate with economic and public environmental attention cycles in the Netherlands. (author)

  7. A study of some political problems considering current geographical analytical parameters

    Directory of Open Access Journals (Sweden)

    Héctor Adolfo Dupuy

    2008-01-01

    Full Text Available This paper intends to study some of the main problems presented, on different scales, by current politics, considering the spatial implications as well as various parameters offered lately by the geographical science. The proposal is supported by the theoretical bases developed from Emmanuel Wallerstein and Peter Taylor's statement about a world system structured as a world economy, based on the capitalist mode of production. Conversely, it attempts to provide a theoretical explanation for the dynamics experienced by the territories upon thee basis of such world system's mechanics. According to these assumptions, an analysis is proposed of some of the main phenomena resulting from the previous analysis and its spatial implications, such as the current power relations in the system, the subsistence of traditional power factors (Nation-states, ethnically based cultural configurations and the appearance of new ones (the forming of transnational blocs and associations, new social movements, new forms of local participation, the importance of hegemonic and counter-hegemonic discourses in the construction of symbolic representations and of the mass media in such processes or the new cultural identity and hybridization chart from population mobility.

  8. Turkish Republic as an Object of Study of US Scienific and Political community: Conceptualization and Methodology of Research

    Directory of Open Access Journals (Sweden)

    Vera A Chmyreva

    2015-12-01

    Full Text Available The article presents the main approaches developed within US scientific and political community concerning the Republic of Turkey and the Middle East region as a whole. These theoretical developments are a long-term conceptual framework of US foreign policy in the Middle East; moreover, the fact of American participation in the processes of political and military transformation of the region, as well as the desire to model the dynamics of these processes, is recognized in modern American historiography. In this context, research of the situation in the region, should be analyzed not through the prism of the theoretical understanding, but be perceived as political technologies designed to ensure the implementation of US foreign policy goals. Therefore the study of American historiography, analysis of new research approaches and methods are of scientific interest, but it must be noted that most research of well-known representatives of American scientific and political community are free from theorizing and methodological analysis, which creates certain difficulties in the study of its methodological framework.

  9. Use of meta-analysis to combine candidate gene association studies: application to study the relationship between the ESR PvuII polymorphism and sow litter size

    Directory of Open Access Journals (Sweden)

    Alfonso Leopoldo

    2005-07-01

    Full Text Available Abstract This article investigates the application of meta-analysis on livestock candidate gene effects. The PvuII polymorphism of the ESR gene is used as an example. The association among ESR PvuII alleles with the number of piglets born alive and total born in the first (NBA1, TNB1 and later parities (NBA, TNB is reviewed by conducting a meta-analysis of 15 published studies including 9329 sows. Under a fixed effects model, litter size values were significantly lower in the "AA" genotype groups when compared with "AB" and "BB" homozygotes. Under the random effects model, the results were similar although differences between "AA" and "AB" genotype groups were not clearly significant for NBA and TNB. Nevertheless, the most noticeable result was the high and significant heterogeneity estimated among studies. This heterogeneity could be assigned to error sampling, genotype by environment interaction, linkage or epistasis, as referred to in the literature, but also to the hypothesis of population admixture/stratification. It is concluded that meta-analysis can be considered as a helpful analytical tool to synthesise and discuss livestock candidate gene effects. The main difficulty found was the insufficient information on the standard errors of the estimated genotype effects in several publications. Consequently, the convenience of publishing the standard errors or the concrete P-values instead of the test significance level should be recommended to guarantee the quality of candidate gene effect meta-analyses.

  10. The role of political efficacy on the relationship between facebook use and participatory behaviors: a comparative study of young American and Chinese adults.

    Science.gov (United States)

    Chan, Michael; Guo, Jing

    2013-06-01

    This comparative study of young adults in an established democracy (America) and transitional democracy (Hong Kong) analyzed the impact of political efficacy on the relationship between Internet/Facebook use on political and civic participation. Regression analyses in both samples showed that Facebook use consistently predicted both types of participation. Moreover, there were significant negative interaction effects of political efficacy and Facebook use on participation, such that the relationship between Facebook use and participation was stronger for those with lower levels of political efficacy. The findings provide cross-cultural support for the argument that social media use among youth can facilitate greater political and civic engagement, particularly for those who perceive that they have limited ability to participate and understand political affairs.

  11. Association study of molecular polymorphisms in candidate genes related to stress responses with production and meat quality traits in pigs.

    Science.gov (United States)

    Terenina, E; Babigumira, B M; Le Mignon, G; Bazovkina, D; Rousseau, S; Salin, F; Bendixen, C; Mormede, P

    2013-02-01

    The hypothalamic-pituitary-adrenal (HPA) axis exerts a large range of effects on metabolism, the immune system, inflammatory processes, and brain functions. Together with the sympathetic nervous system, it is also the most important stress-responsive neuroendocrine system. Both systems influence production traits, carcass composition, and meat quality. The HPA axis may be a critical target for genetic selection of more robust animals. Indeed, numerous studies in various species have demonstrated the importance of genetic factors in shaping the individual HPA axis phenotype, and genetic polymorphism can be found at each level of the axis, including hormone production by the adrenal cortices under stimulation by adrenocorticotropic hormone (ACTH), hormone bioavailability, or receptor and postreceptor mechanisms. The aim of the present experiment was to extend these findings to the brain neurochemical systems involved in stress responses. To this end, a number of candidate genes were sequenced for molecular polymorphisms and their association was studied with stress neuroendocrine and production traits in a genetically diverse population consisting of 100 female pigs from an advanced intercross (F10-F12) between 2 highly divergent breeds, Large White (LW) and Meishan (MS). The LW breed has a high production potential for lean meat and a low HPA axis activity, and the MS breed has low growth rate, fat carcasses-but large litters of highly viable piglets-and a high HPA axis activity. Candidate genes were chosen in the catecholaminergic and serotonergic pathways, in the pituitary control of cortisol production, among genes previously demonstrated to be differentially expressed in ACTH-stimulated adrenal glands from LW and MS pigs, and in cortisol receptors. Sixty new polymorphisms were found. The association study with carcass and meat quality traits and with endocrine traits showed a number of significant results, such as monoamine oxidase (MAOA) polymorphisms with

  12. Haplotype-based genome-wide association study identifies loci and candidate genes for milk yield in Holsteins.

    Directory of Open Access Journals (Sweden)

    Zhenliang Chen

    Full Text Available Since milk yield is a highly important economic trait in dairy cattle, the genome-wide association study (GWAS is vital to explain the genetic architecture underlying milk yield and to perform marker-assisted selection (MAS. In this study, we adopted a haplotype-based empirical Bayesian GWAS to identify the loci and candidate genes for milk yield. A total of 1 092 Holstein cows were sequenced by using the genotyping by genome reducing and sequencing (GGRS method. After filtering, 164 312 high-confidence SNPs and 13 476 haplotype blocks were identified to use for GWAS. The results indicated that 17 blocks were significantly associated with milk yield. We further identified the nearest gene of each haplotype block and annotated the genes with milk-associated quantitative trait locus (QTL intervals and ingenuity pathway analysis (IPA networks. Our analysis showed that four genes, DLGAP1, AP2B1, ITPR2 and THBS4, have relationships with milk yield, while another three, ARHGEF4, TDRD1 and KIF19, were inferred to have potential relationships. Additionally, a network derived from the IPA containing one inferred (ARHGEF4 and all four confirmed genes likely regulates milk yield. Our findings add to the understanding of identifying the causal genes underlying milk production traits and could guide follow up studies for further confirmation of the associated genes, pathways and biological networks.

  13. Genome-Wide Association Study with Sequence Variants Identifies Candidate Genes for Mastitis Resistance in Dairy Cattle

    DEFF Research Database (Denmark)

    Sahana, Goutam; Guldbrandtsen, Bernt; Bendixen, Christian

    component in a linear mixed model. A total of 90 bulls’ whole genomes were sequenced with a coverage > 10X. Sequence reads were aligned to the cattle reference genome and polymorphisms in candidate regions were identified when one or more samples differed from the reference sequence. The polymorphisms...... Factor Receptor Alpha (LIFR) emerged as a strong candidate gene for mastitis resistance. The LIFR gene is involved in acute phase response and is expressed in saliva and mammary gland....

  14. Evolution in the enunciative structure of the political discourse

    Directory of Open Access Journals (Sweden)

    Joanna Jereczek-Lipińska

    2012-01-01

    Full Text Available This study is based upon discursive and logometric analysis of the political speeches delivered by the candidates during the campaign and pre-campaign phases of the 2012 presidential elections in France, taking into account the results of previous studies related to the 2007 presidential elections. The present paper aims at tracing the different representations of the speaker within his own speeches and at analyzing the way he verbalizes himself in his campaign by observing the use, the distribution, the role and the possible impact of “I” and of the other personal pronouns within the frame of political communication. The analysis of statistical data tends to emphasize syntactic as well as morphological, stylistic, lexical, and gramatical distinctive features of the speeches delivered by the candidates to the presidential elections, especially in relation with the new possibilities conveyed by internet.

  15. Fuel for Debate: Three Studies of the Political Mobilization for and against Hydraulic Fracturing in New York State

    Science.gov (United States)

    Dokshin, Fedor Aleksandrovich

    This dissertation uses the context of the unfolding boom in oil and gas production enabled by hydraulic fracturing ("fracking") technology to ask several interrelated questions: What motivates people to oppose or support industrial development? How do material interests interact with political identities to shape political mobilization? What consequences does this political contestation have for policymaking? Three stand-alone articles, each using unique data and methods, provide new evidence for answering these questions. The three studies place a common emphasis on the multiple meanings that fracking has for opponents and supporters of proposed development as well as the alternative structural conditions that give rise to the divergent beliefs and the social networks that facilitate mobilization. The first article, examines the passage of local zoning ordinances prohibiting fracking and identifies spatial and temporal processes that influenced the pattern of ordinance adoption. The second article, looks more closely at political mobilization for and against hydraulic fracturing by examining individual-level data collected from one town's debate over a proposed ban on oil and gas development. The third article uses a large set of public comments to directly examine the meanings that the public attached to hydraulic fracturing and whether residents who live in close proximity to proposed development understood the industry in systematically different terms than individuals who participated in the debate despite facing little or no direct impact from fracking.

  16. Populism and Anti-Establishment Politics in Kosovo: A Case Study of Lëvizja Vetëvendosje

    Directory of Open Access Journals (Sweden)

    Bilge Yabanci

    2016-12-01

    Full Text Available Few studies have systematically examined the rising political and social unrest in the Balkans. This paper investigates the local dynamics and consequences of widespread anti-establishment discontent in Kosovo through the analytical framework of populism. By focusing on the case of Lëvizja Vetëvendosje (LVV, the paper sets out to consider two related questions: the unique populist style of the LVV and the complex reasons behind its electoral breakthrough and continuing support among various groups. Based on a qualitative documentary analysis of the party programme, manifesto, party publications, speeches of the leadership and interviews, the paper finds that the LVV successfully melds a populist political style, leftist/social democratic agenda and contentious politics as a means to disperse its message. The second part of the article offers three arguments to explain its appeal: structural factors (electoral availability and party system, societal dynamics (political and economic dissatisfaction and the agency of the LVV (internal organisation, cohesion and leadership. The article contributes to the thriving literature on populism through a novel empirical scope, and to the literature on Southeast Europe through a focus on local agency, voter preferences and party system.

  17. The Influence of Liberal Studies on Students' Participation in Socio-Political Activities: The Case of the Umbrella Movement in Hong Kong

    Science.gov (United States)

    Fung, Dennis; Su, Angie

    2016-01-01

    This paper reports an investigation into how secondary student participants in Hong Kong's Umbrella Movement related this particular political experience to their learning of Liberal Studies. Questionnaire-based surveys and interviews were conducted to probe their interpretations of Liberal Studies' impact on their political involvement and their…

  18. Politics and society: for a return to political sociology

    OpenAIRE

    Perissinotto, Renato Monseff; Universidade Federal do Paraná

    2004-01-01

    The purpose of this essay is to make some considerations on the limits and advantages of institutionalism’s rational choice in regard to the understanding of political phenomena. The text critically examines some of the representative studies that Brazilian political science has attached to this theoretical approach. This criticism develops around three themes: state, political elites and democracy. It suggests that a prudent return to the approach of political sociology wou...

  19. Political Power and Violence

    Directory of Open Access Journals (Sweden)

    Bianca Mitu

    2011-10-01

    Full Text Available Political violence plays a huge role in public affairs and people's behavior, requiring both knowledge and rigorous research in many of its occurrences and its consequences for the proper management, organization and functioning of a society as a whole. Although political violence is a problem of a particular importance in our social life it is not analyzed and investigated in the scientific literature. Political violence it is a subject that usually passes into oblivion. This study presents some ideas and themes about the role and functions of political power, displaying the types of political violence and their consequences for the management and functioning of a society, which can be subject to wider debates and researchs.

  20. Distinguishing between cancer driver and passenger gene alteration candidates via cross-species comparison: a pilot study

    International Nuclear Information System (INIS)

    Ji, Xinglai; Tang, Jie; Halberg, Richard; Busam, Dana; Ferriera, Steve; Peña, Maria Marjorette O; Venkataramu, Chinnambally; Yeatman, Timothy J; Zhao, Shaying

    2010-01-01

    We are developing a cross-species comparison strategy to distinguish between cancer driver- and passenger gene alteration candidates, by utilizing the difference in genomic location of orthologous genes between the human and other mammals. As an initial test of this strategy, we conducted a pilot study with human colorectal cancer (CRC) and its mouse model C57BL/6J Apc Min/+ , focusing on human 5q22.2 and 18q21.1-q21.2. We first performed bioinformatics analysis on the evolution of 5q22.2 and 18q21.1-q21.2 regions. Then, we performed exon-targeted sequencing, real time quantitative polymerase chain reaction (qPCR), and real time quantitative reverse transcriptase PCR (qRT-PCR) analyses on a number of genes of both regions with both human and mouse colon tumors. These two regions (5q22.2 and 18q21.1-q21.2) are frequently deleted in human CRCs and encode genuine colorectal tumor suppressors APC and SMAD4. They also encode genes such as MCC (mutated in colorectal cancer) with their role in CRC etiology unknown. We have discovered that both regions are evolutionarily unstable, resulting in genes that are clustered in each human region being found scattered at several distinct loci in the genome of many other species. For instance, APC and MCC are within 200 kb apart in human 5q22.2 but are 10 Mb apart in the mouse genome. Importantly, our analyses revealed that, while known CRC driver genes APC and SMAD4 were disrupted in both human colorectal tumors and tumors from Apc Min/+ mice, the questionable MCC gene was disrupted in human tumors but appeared to be intact in mouse tumors. These results indicate that MCC may not actually play any causative role in early colorectal tumorigenesis. We also hypothesize that its disruption in human CRCs is likely a mere result of its close proximity to APC in the human genome. Expanding this pilot study to the entire genome may identify more questionable genes like MCC, facilitating the discovery of new CRC driver gene candidates

  1. Current methodological questions of studying social-political relations of global society

    Directory of Open Access Journals (Sweden)

    Marković Danilo Ž.

    2010-01-01

    Full Text Available Identification and critical study of social-political aspects of contemporary society within conditions of globalization must start from the characteristics (essence of globalization as a process of human kind consolidation. Globalization represents a process of economic, political and cultural connecting of all separate mankind societies (specific societies into the one whole, into a 'World' - 'Global' society (mega-society on the Planet with many contradictions. It is a meaningful way for money to bring profit in a peaceful manner. It leads not only to expanding of economic power through transnational and multinational economic corporations, but also to imposing way of life, social organization and categorized value system of countries - protagonists of globalization to others, as indicators of their creative capabilities and specific forms of their appearance, specialty and durability. These and other changes, as well as multiple and versatile consequences that accompany them, indicate the necessity of constructing a new social approach in their scientific cognition, with full respect of not only social but also natural laws on cognition and estimation of accomplishing social life. The social and especially sociological sciences should investigate and excogitate the next areas of global reality of contemporary society in this context. Macrostructures in the architecture of its construction: world community, socio-economic system that appears with globalization process and international community that appears by agreement between the states, their dynamic relationship and influence on flows and future of mankind civilization and social position of human. Diversity of the forms of cooperation, conflicts and collisions in the 'world' society and possibility of war conflicts regarding safety of not only specific people, regions and states, but also regarding the survival of human civilization, since it is obvious that such a conflict would have

  2. Problems and pit-falls in testing for G × E and epistasis in candidate gene studies of human behavior.

    Science.gov (United States)

    Eaves, Lindon; Verhulst, Brad

    2014-11-01

    Conclusions about the genetic architecture of a phenotype relating to the contributions of genetic additivity, dominance, epistasis or genotype × environment interaction, depend upon the statistical and distributional properties of the measured trait. This dependence is frequently ignored in contemporary genetic studies and can radically change the conclusions that may be drawn from the data. The interdependence of the conclusions about genetic architecture and instruments used for behavioral measurement is explored by simulated studies of the interaction between candidate genes and measured environment in psychiatric genetics. Trait values are simulated (N = 100,000) under several commonly encountered scenarios and subjected to two simulated 20-item psychological tests each comprising items with different patterns of difficulty and sensitivity to variation (discriminating power) in the latent trait. Test scores are generated for each test by summing the binary responses across all items. The full model for digenic additive and non-additive genetic effects and G × E is fitted to the trait values and test scores under a range of different simulated genetic architectures. Untransformed test scores show complex patterns of epistasis and G × E even when the underlying effects of genes and environment are purely additive and the transformation of symptom counts does not fully recover the simulated underlying genetic architecture. Accordingly, failing to allow for the theory of measurement when analyzing details of genetic architecture may frequently lead to replicable over-reporting of interactions and mislead potential investigators and funding agencies.

  3. A Test-Replicate Approach to Candidate Gene Research on Addiction and Externalizing Disorders: A Collaboration Across Five Longitudinal Studies.

    Science.gov (United States)

    Samek, Diana R; Bailey, Jennifer; Hill, Karl G; Wilson, Sylia; Lee, Susanne; Keyes, Margaret A; Epstein, Marina; Smolen, Andrew; Miller, Michael; Winters, Ken C; Hawkins, J David; Catalano, Richard F; Iacono, William G; McGue, Matt

    2016-09-01

    This study presents results from a collaboration across five longitudinal studies seeking to test and replicate models of gene-environment interplay in the development of substance use and externalizing disorders (SUDs, EXT). We describe an overview of our conceptual models, plan for gene-environment interplay analyses, and present main effects results evaluating six candidate genes potentially relevant to SUDs and EXT (MAOA, 5-HTTLPR, COMT, DRD2, DAT1, and DRD4). All samples included rich longitudinal and phenotypic measurements from childhood/adolescence (ages 5-13) through early adulthood (ages 25-33); sample sizes ranged from 3487 in the test sample, to ~600-1000 in the replication samples. Phenotypes included lifetime symptom counts of SUDs (nicotine, alcohol and cannabis), adult antisocial behavior, and an aggregate externalizing disorder composite. Covariates included the first 10 ancestral principal components computed using all autosomal markers in subjects across the data sets, and age at the most recent assessment. Sex, ancestry, and exposure effects were thoroughly evaluated. After correcting for multiple testing, only one significant main effect was found in the test sample, but it was not replicated. Implications for subsequent gene-environment interplay analyses are discussed.

  4. Processing political misinformation: comprehending the Trump phenomenon.

    Science.gov (United States)

    Swire, Briony; Berinsky, Adam J; Lewandowsky, Stephan; Ecker, Ullrich K H

    2017-03-01

    This study investigated the cognitive processing of true and false political information. Specifically, it examined the impact of source credibility on the assessment of veracity when information comes from a polarizing source (Experiment 1), and effectiveness of explanations when they come from one's own political party or an opposition party (Experiment 2). These experiments were conducted prior to the 2016 Presidential election. Participants rated their belief in factual and incorrect statements that President Trump made on the campaign trail; facts were subsequently affirmed and misinformation retracted. Participants then re-rated their belief immediately or after a delay. Experiment 1 found that (i) if information was attributed to Trump, Republican supporters of Trump believed it more than if it was presented without attribution, whereas the opposite was true for Democrats and (ii) although Trump supporters reduced their belief in misinformation items following a correction, they did not change their voting preferences. Experiment 2 revealed that the explanation's source had relatively little impact, and belief updating was more influenced by perceived credibility of the individual initially purporting the information. These findings suggest that people use political figures as a heuristic to guide evaluation of what is true or false, yet do not necessarily insist on veracity as a prerequisite for supporting political candidates.

  5. Evaluation of GWAS candidate susceptibility loci for uterine leiomyoma in the multi-ethnic NIEHS uterine fibroid study

    Directory of Open Access Journals (Sweden)

    Brahim eAissani

    2015-07-01

    Full Text Available We evaluated the association of 56 candidate SNPs identified in two published genome-wide association studies (GWAS of uterine leiomyoma (UL, or fibroids, with the risk and tumor size in the multi-ethnic uterine fibroid study (NIEHS-UFS. The selected SNPs were genotyped in 916 premenopausal women of African American (AA and European American (EA descents and their association with the outcomes was evaluated in race-stratified models and in meta-analysis of risk in NIEHS-UFS and discovery and replication GWAS in the Japanese population. We report moderate associations of variant rs4954368 in THSD7B (thrombospondin, type I, domain containing 7B with tumor size in pooled analysis of AA and EA samples (P = 0.004, and at TNRC6B (trinucleotide repeat containing 6B variants rs138039 and rs139909 in EA (P = 0.001 and P = 0.008, respectively. The most significant associations with risk in meta-analysis were observed at TNRC6B variants rs739182 (P = 3.7 x 10-10 and rs2072858 (P = 1.1 x 10-9 and were stronger than those reported in the discovery GWAS (P =2.01 x 10-8 and P = 2.58 x 10-8, respectively. The present study failed to replicate the associations reported for CCDC57 and FASN in a discovery GWAS in populations of European descent. Consistent with previous replication studies in the Right From the Start Study (RFTS and the BioVU DNA repository, we provide independent evidence for association of TNRC6B with both risk and size of UL. The present study is the first to report a replicated association of THSD7B with UL, albeit with tumor size and not with risk.

  6. Topic Signatures in Political Campaign Speeches

    OpenAIRE

    Gautrais , Clément; Cellier , Peggy; Quiniou , René; Termier , Alexandre

    2017-01-01

    International audience; Highlighting the recurrence of topics usage in candidates speeches is a key feature to identify the main ideas of each candidate during a political campaign. In this paper, we present a method combining standard topic modeling with signature mining for analyzing topic recurrence in speeches of Clinton and Trump during the 2016 American presidential campaign. The results show that the method extracts automatically the main ideas of each candidate and, in addition, provi...

  7. WOMEN IN POLITICS IN GHANA A Study on Local Government in ...

    African Journals Online (AJOL)

    UDS-CAPTURED

    Women's participation in politics in Ghana is low, both at local and the national level. This reflects the global trend of women's ... Women in Ghana earned low incomes coupled with low educational status. Also, lack of confidence was found to be a ..... Migration for Employment.' In A. Adepoju and Christine Oppong (eds).

  8. Environmental NGOs and the Bio-safety Protocol. A case study on political influence

    NARCIS (Netherlands)

    Arts, B.J.M.; Mack, S.

    2003-01-01

    It is not only governments which play an important role in securing international agreements, but environmental non-governmental organizations (ENGOs) as well. This is reflected in the ever-growing body of literature concerning this topic. This article deals with the political influence of ENGOs on

  9. Oil Politics and its Social Implications in the Niger Delta: A Study of ...

    African Journals Online (AJOL)

    info

    in terms of the people's reaction in the face of this ''death by instalment''. Other writers in the region have ... exploration by Shell usually on the orders of political leaders both in the military and. 'democratic' dispensations whose ... the Niger Delta having most senior military officers on its payrolls. SHELL LOVES THE DELTA.

  10. Enacting Third-Party Certification: A Case Study of Science and Politics in Organic Shrimp Certification

    Science.gov (United States)

    Konefal, Jason; Hatanaka, Maki

    2011-01-01

    As third-party certification has become a prominent governance mechanism, conflicting understandings of it have emerged. Proponents advance third-party certification as a technical and objective governance mechanism, while critics argue that politics and relations of power characterize it. We reject this dichotomization both in terms of how TPC is…

  11. Political Youth Education in Germany. Presenting a Qualitative Study on Its Biographically Long-Term Effects

    Science.gov (United States)

    Balzter, Nadine; Ristau, Yan; Schröder, Achim

    2017-01-01

    Purpose: There is an impact analysis presented, which explores the long-term effect of extra-curricular political youth education from the perspective of participants. Methods: The former participants retell their own education and life stories about five years later. Life stories were then interpreted in the course of research workshops and…

  12. The Dramatist and His Praxis: A Comparative Study of the Political ...

    African Journals Online (AJOL)

    There seems to be a comparable personal circumstance between the Attic dramatist, Euripides, and the Nigerian dramatist, Wole Soyinka on one hand, and between Soyinka and the popular dramatist, Hubert Ogunde on the other. They all appeared to be actively involved in the politics of their time and society. However ...

  13. The Language of Satire in Nigerian Politics: A Study of the Syntactic ...

    African Journals Online (AJOL)

    They are not only exploiting Nigerians, but have plunged them into abject poverty and hardship through corrupt practices and bad governance. Unlike what obtains in many developed countries, politics in Nigeria like in most African countries is characterized by corrupt practices due to avarice and greed associated with ...

  14. Verbal hygiene and ethnic politics in Nigeria: a study of selected ...

    African Journals Online (AJOL)

    The collected data were textually analyzed through the lens of Politeness Theory of Brown and Levinson. It was found that a strong relationship exists between poor verbal hygiene, hate speech, electoral violence and ethnicity in Nigeria. This work also found out that the speeches of most opinion leaders analysed in this ...

  15. Thinking Whimsically: Queering the Study of Educational Policy-Making and Politics

    Science.gov (United States)

    Lugg, Catherine A.; Murphy, Jason P.

    2014-01-01

    This paper discusses employing queer theory (QT) and queer legal theory (QLT) for critical policy analysis as applied to education. In doing so, the authors will highlight how both QT and QLT can empower analyses to look beyond the identity politics of a particular time period or space and toward potential reforms in curriculum, pedagogy, and…

  16. Longing for Wikitopia: the study and politics of self-organization

    NARCIS (Netherlands)

    Uitermark, J.

    2015-01-01

    Self-organisation is an idea whose time has come. As an explanatory concept, self-organisation is central to complexity theory, which is quickly becoming a powerful and perhaps even dominant paradigm in both the natural and social sciences. As a political ideal, self-organisation is filling the void

  17. Political Studies: An Entry into "Social Science Thought" in the South African Academy

    Science.gov (United States)

    Tselapedi, Thapelo

    2016-01-01

    This paper briefly examines the epistemic orientation of the Politics discipline in South Africa, and specifically in "formerly white universities". The focus is to expose the disparity between this epistemic orientation and the South African locale that it finds itself in; that is, a locale whose history is different from its…

  18. HA03 as an Iranian Candidate Concealed Antigen for Vaccination against Hyalomma anatolicum anatolicum: Comparative Structural and In silico Studies

    Directory of Open Access Journals (Sweden)

    Mohammadi, A.

    2013-12-01

    Full Text Available In the last decades researchers had focused on developing a vaccine against tick based on protective antigen. Recombinant vaccines based on concealed antigen from Boophilus microplus have been developed in Australia and Cuba by the name of TICKGARD and GAVAC (De La Fuente and Kocan, 2006. Further studies on this antigen have shown some extent of protection against other species (De Vos et al., 2001. In Iran most important species is Hyalomma anatolicum and limited information about its control are available. This paper reports structural and polymorphic analysis of HA03 as an Iranian candidate concealed antigen of H. a. anatolicum deposited in Gen-Bank .(Aghaeipour et al. GQ228820. The comparison between this antigen and other mid gut concealed antigen that their characteristics are available in GenBank showed there are high rate of similarity between them. The HA03 amino acid sequence had a homology of around 89%, 64%, 56% with HA98, BM86, BM95 respectively. Potential of MHC class I and II binding region indicated a considerable variation between BM86 antigen and its efficiency against Iranian H. a. anatolicum. In addition, predicted major of hydrophobisity and similarity in N-glycosylation besides large amount of cystein and seven EGF like regions presented in protein structure revealed that value of HA03 as a new protective antigen and the necessity of the development, BM86 homolog of H. a. anatolicum HA03 based recombinant vaccine.

  19. Evaluation of the SIPAT instrument to assess psychosocial risk in heart transplant candidates: A retrospective single center study.

    Science.gov (United States)

    Vandenbogaart, Elizabeth; Doering, Lynn; Chen, Belinda; Saltzman, Ann; Chaker, Tamara; Creaser, Julie W; Rourke, Darlene; Cheng, Richard W; Fonarow, Gregg C; Deng, Mario

    We evaluated the reliability of the Stanford Integrated Psychosocial Assessment for Transplantation (SIPAT) in heart transplant (HT) recipients and explored its usefulness in predicting post-transplant outcomes. Pre-transplant psychosocial and behavioral risk is associated with post-transplant clinical outcomes. SIPAT is a risk assessment tool created for pre-transplant psychosocial evaluation. Via retrospective chart review, three examiners applied the SIPAT to 51 adult HT recipients. Examiners blinded to SIPAT scores extracted data and interviewed clinicians for one-year post-transplant outcomes. Analysis included Intra-class correlation coefficient (ICC), Pearson's correlation coefficient and Chi-square. SIPAT demonstrated strong inter-rater reliability (ICC = 0.89, 95% CI = 0.76-0.96). Compared to those with SIPAT ratings of "Excellent/Good", the "Minimally Acceptable Candidate/High Risk" group was more likely to miss clinic visits (p = 0.004). The SIPAT tool had strong IRR. Less favorable SIPAT ratings were associated with nonadherence to clinic visits. Further study is warranted to determine association of SIPAT ratings to clinical outcomes. Copyright © 2017 Elsevier Inc. All rights reserved.

  20. Important Factors in the Cognitive Development of Children with Hearing Impairment: Case Studies of Candidates for Cochlear Implants

    Directory of Open Access Journals (Sweden)

    Nasralla, Heloisa Romeiro

    2014-06-01

    Full Text Available Introduction The factors that affect the development of children with and without hearing disabilities are similar, provided their innate communication abilities are taken into account. Parents need to mourn the loss of the expected normally hearing child, and it is important that parents create bonds of affection with their child. Objective To conduct a postevaluation of the development and cognition of 20 candidates for cochlear implants between 1 and 13 years of age and to observe important factors in their development. Methods The following instruments were used in accordance with their individual merits: interviews with parents; the Vineland Social Maturity Scale; the Columbia Maturity Scale; free drawings; Bender and Pre-Bender testing; and pedagogical tests. Results The results are described. Conclusion Parental acceptance of a child's deafness proved to be the starting point for the child's verbal or gestural communication development, as well as for cognitive, motor, and emotional development. If the association between deafness and fine motor skills (with or without multiple disabilities undermines the development of a child's speech, it does not greatly affect communication when the child interacts with his or her peers and receives maternal stimulation. Overprotection and poor sociability make children less independent, impairs their development, and causes low self-esteem. Further observational studies are warranted to determine how cochlear implants contribute to patient recovery.

  1. Bridging Worlds in the Social Studies Classroom:Teachers' Practices and Latino Immigrant Youths' Civic and Political Development.

    Science.gov (United States)

    Callahan, Rebecca M; Obenchain, Kathryn M

    2013-01-01

    Prior research suggests that high school experiences shape young adult political behaviors, particularly among immigrant youth. The U.S. social studies classroom, focused on democratic citizenship education, proves an interesting socializing institution. Through qualitative inquiry, we interviewed Latino immigrant young adults and their former teachers regarding their high school social studies experiences and evolving political and civic engagement. indicate that armed with experience bridging the worlds of the school and home, immigrant students respond and relate to the content and pedagogy of the social studies classroom in such a way that they (1) participate in civic discourse and (2) nurture a disposition toward leadership through teachers' civic expectations of them and instructional emphasis on critical thinking skills. The ability to engage in civic discourse and a disposition toward leadership are both necessary to foster America's democratic ideals, and to take on leadership roles during adulthood. With focused effort on the unique perspective of immigrant youth, high school social studies teachers can nurture in these students the ability to become leaders in young adulthood, broadening the potential leadership pool. This study highlights how the social studies curriculum may be particularly salient to Latino immigrant youth as they transition from adolescence to young adulthood and develop their political and civic identities.

  2. Integrative species delimitation in photosynthetic sea slugs reveals twenty candidate species in three nominal taxa studied for drug discovery, plastid symbiosis or biological control.

    Science.gov (United States)

    Krug, Patrick J; Vendetti, Jann E; Rodriguez, Albert K; Retana, Jennifer N; Hirano, Yayoi M; Trowbridge, Cynthia D

    2013-12-01

    DNA barcoding can highlight taxa in which conventional taxonomy underestimates species richness, identifying mitochondrial lineages that may correspond to unrecognized species. However, key assumptions of barcoding remain untested for many groups of soft-bodied marine invertebrates with poorly resolved taxonomy. Here, we applied an integrative approach for species delimitation to herbivorous sea slugs in clade Sacoglossa, in which unrecognized diversity may complicate studies of drug discovery, plastid endosymbiosis, and biological control. Using the mitochondrial barcoding COI gene and the nuclear histone 3 gene, we tested the hypothesis that three widely distributed "species" each comprised a complex of independently evolving lineages. Morphological and reproductive characters were then used to evaluate whether each lineage was distinguishable as a candidate species. The "circumtropical" Elysia ornata comprised a Caribbean species and four Indo-Pacific candidate species that are potential sources of kahalalides, anti-cancer compounds. The "monotypic" and highly photosynthetic Plakobranchus ocellatus, used for over 60 years to study chloroplast symbiosis, comprised 10 candidate species. Finally, six candidate species were distinguished in the Elysia tomentosa complex, including potential biological control agents for invasive green algae (Caulerpa spp.). We show that a candidate species approach developed for vertebrates effectively categorizes cryptic diversity in marine invertebrates, and that integrating threshold COI distances with non-molecular character data can delimit species even when common assumptions of DNA barcoding are violated. Copyright © 2013 Elsevier Inc. All rights reserved.

  3. Spiritual Politics

    Directory of Open Access Journals (Sweden)

    Frédéric Rambeau

    2015-01-01

    Full Text Available According to Foucault, the uprising of the Iranian people in the seventies reveals how much the political force of Islam is due precisely to the fact that it is not principally located in the field of politics, but in that of ethics. Religion (Shiite Islam appears as the guarantee of real change in the very mode of existence. This spiritual politics is marginalized by Marxism, where it is understood as a discontinuity in relation to proper politics, given that the latter is necessarily linked to a strategic rationalization. By indicating, at this juncture of what is intolerable, the living source and the critical impulse of the Foucauldian ethics, this spiritual politics also leads to recognize in the concept of “subjectivation” a dimension that might escape the circle of freedom as determined by a total immanence to power. This conceptual possibility is highly present in the aporias of the Foucauldian concept of the “relation to oneself”, both as a first condition of governmentality and the ultimate point of resistance against any governmentality. It thus reveals the difficulties in relating political to ethical subjectivation.

  4. Political dynamics of economic sanctions: a case study of Arab oil embargoes

    Energy Technology Data Exchange (ETDEWEB)

    Daoudi, M.S.

    1981-01-01

    The general question is considered of the effectiveness of economic sanctions in international politics, in terms of the Arabs' use of oil as a political weapon in 1956, 1967, and 1973. Chapter 3 focuses on the impact of the interruption of oil supplies to Western Europe throughout the 1956 Suez crisis. By 1967, pressure on the conservative governing elites of Saudi Arabia, Kuwait, Libya, and the Gulf Sheikdoms obliged these states to join Iraq and Algeria in imposing production cutbacks and an embargo. Yet the conservative regimes' ties to the West, and the control exerted by multinational oil corporations over all phases of their oil industry, insured that the embargo was not enforced. Chapter 4 explains historically how, by the late 1960s, relinquishment of old concessions, nationalization acts, and participation agreements had caused a decline in the multinationals' domination of the oil industry. The rise of OPEC and OAPEC, which by 1970 had united and organized the producing governments, channeled their demands, and created an international forum for their political grievances, is discussed. Chapter 5 considers how by 1973 international and Arab political developments had forced states like Saudi Arabia, which had sought to dissociate oil and politics, to unsheathe the oil weapon and wave it in the faces of their Western allies. The author concludes from analysis of these complex cases that scholarship has exaggerated the inefficacy of sanctions. The effectiveness of sanctions is seen to depend upon how the demands are formulated and presented and to what extent they can be negotiated, as well as upon the sociopolitical, cultural, and psychological characteristics of the target population.

  5. A Political Innovator?

    DEFF Research Database (Denmark)

    Tang, Yi; Lin, Yu; Andersen, Torben Juul

    2016-01-01

    Political networking is frequently used in transition economies to gain superior performance. This study draws on upper echelons theory (UET) and the resource-based view (RBV) to analyze the relationship between political networking and firm innovation moderated by the core self-evaluation (CSE......) of the CEO. Based on a sample of 381 manufacturing firms extracted from the Entrepreneurs Survey System of Chinese CEOs with 2014 data from the Jiangsu province, the study finds that political networking is positively related to explorative and exploitative innovation but negatively moderated by the CSE...

  6. HIV-infection, atherosclerosis and the inflammatory pathway: candidate gene study in a Spanish HIV-infected population.

    Directory of Open Access Journals (Sweden)

    Laura Ibáñez

    Full Text Available BACKGROUND: Higher prevalence of atherosclerosis and higher cardiovascular risk is observed in HIV-infected individuals. The biological mechanisms underlying these processes are unclear. Several studies have implicated genetic variants in the inflammatory genes in cardiovascular disease and in HIV natural course infection. METHODS & FINDINGS: In this study we have tested the possible association between genetic variants in several inflammatory genes and asymptomatic cardiovascular disease measured by carotid intima media thickness (cIMT and atherosclerotic plaque presence as dependent variables in 213 HIV-infected individuals. A total of 101 genetic variants in 25 candidate genes have been genotyped. Results were analyzed using Plink and SPSS statistical packages. We have found several polymorphisms in the genes ALOX5 (rs2115819 p = 0.009, ALOX5AP (rs9578196 p = 0.007; rs4769873 p = 0.004 and rs9315051 p = 0.0004, CX3CL1 (rs4151117 p = 0.040 and rs614230 p = 0.015 and CCL5 (rs3817655 p = 0.018 and rs2107538 p = 0.018 associated with atherosclerotic plaque. cIMT mean has been associated with CRP (1130864 p = 0.0003 and rs1800947 p = 0.008, IL1RN (rs380092 p = 0.002 and ALOX5AP (rs3885907 p = 0.02 genetic variants. CONCLUSIONS: In this study we have found modest associations between genetic variants in several inflammatory genes and atherosclerotic plaque or cIMT. Nevertheless, our study adds evidence to the association between inflammatory pathway genetic variants and the atherosclerotic disease in HIV-infected individuals.

  7. Televised Political Advertising and the Voter: A Survey of Voter Attitudes in the 1972 Presidential Campaign.

    Science.gov (United States)

    Nayman, Oguz B.

    During the recent election campaigns in the United States, speculative arguments about the use or the abuse of televised political spot commercials to "package" and "sell" the candidates to the public were widespread. With this popularly held belief in mind, the present study concerned itself with the reactions to and utilization of televised…

  8. A Comparison of the Two-Party and Multi-Party Political Systems: A Case Study Using the United States and West Germany.

    Science.gov (United States)

    Garland, James

    The political system of the Federal Republic of Germany (West Germany) is explained and comparisons are made with the U.S. system. Descriptions are given of the West German political parties and the process and importance of forming coalitions is explained. A lesson plan is presented that utilizes the case study and includes a simulation exercise…

  9. Democracy as a Contested Concept in Postwar Western Europe: A Comparative Study of Political Debates in France, West Germany and Italy

    NARCIS (Netherlands)

    Corduwener, P.

    2016-01-01

    This article explores how political parties in France, West Germany, and Italy conceptualized democracy and challenged the conceptions of democracy of their political adversaries between the end of the 1940s and the early 1960s. It studies from a comparative perspective the different conceptions of

  10. Elections, Information, and State-Dependent Candidate Quality

    DEFF Research Database (Denmark)

    Jensen, Thomas

    The quality of political candidates often depends on the current state of the world, for example because their personal characteristics are more valuable in some situations than in others. We explore the implications of state-dependent candidate quality in a model of electoral competition where...

  11. Audience Responses and the Context of Political Speeches

    Directory of Open Access Journals (Sweden)

    Hyangmi Choi

    2016-11-01

    Full Text Available Previous studies showed that cultural dimensions (individualism and collectivism are related to audience behavior in responding to political speeches. However, this study suggests that speech context is an important issue to be considered in understanding speaker-audience interaction in political speeches. Forms of response, audience behavior, and response rates were analyzed in three speech contexts: acceptance speeches to nomination as political parties’ candidates for presidential election, presidential election campaign speeches, and presidential inauguration speeches in the Korean presidential election of 2012. We found that audience response forms and behavior were distinctive according to the three speech contexts: in-group partisan leadership, competitive, and formal contexts. However, there was no relationship between the affiliative response rate and electoral success in the election. The function of the audience response is popularity and support of a speaker in acceptance and election campaign speeches, while it is conformity to social norms in inauguration speeches.

  12. 'I Will Crawl Before You' Political endorsements, defections and ...

    African Journals Online (AJOL)

    While public endorsement of presidential candidates is a relatively new phenomenon in Zambian politics, political defections have existed for a longer period. However, both of these political manoeuvres have increasingly become ubiquitous since Zambia's return to multiparty democracy in the 1990s. Often, defectors prey ...

  13. Training the Next Generation of Teaching Professors: A Comparative Study of Ph.D. Programs in Political Science

    Science.gov (United States)

    Ishiyama, John; Miles, Tom; Balarezo, Christine

    2010-01-01

    In this article, we investigate the graduate curricula of political science programs and 122 Ph.D.-granting political science programs in the United States and how they seek to prepare political science teachers. We first investigate whether the department offers a dedicated political science course at the graduate level on college teaching, and…

  14. Generating Political Priority to Tackle Health Disparities: A Case Study in the Dutch City of The Hague

    Science.gov (United States)

    Joosen, Isabel; Kunst, Anton E.; Klazinga, Niek S.; Stronks, Karien

    2010-01-01

    Objectives. We sought to study the factors that determined the success of a recent initiative to generate political priority for the problem of health disparities in the city of The Hague, the Netherlands. Methods. Our study had a prospective design. The qualitative data collection included interviews, document analyses, and observations. Results. Crucial for the success of this initiative was the presence of powerful and credible actors. These actors effectively presented scientific evidence on health disparities and framed the issue in the light of shared values, priorities, and policy principles. Finally, their actions were supported by the national context, including the availability of national scientific research on health disparities. Conclusions. The project in The Hague shows that political priority for tackling health disparities can be generated at a local level. Key factors included framing the issue in the light of shared values and framing the problem and the solution as in line with existing policy principles. PMID:20147684

  15. Coming of Age in U.S. High Schools: Economic, Kinship, Religious, and Political Crosscurrents. Sociocultural, Political, and Historical Studies in Education Series

    Science.gov (United States)

    Hemmings, Annette B.

    2004-01-01

    This book takes readers into the lives of urban and suburban adolescents for a close-up look at how they navigate the conflicting discourses and disciplinary practices of American cultural crosscurrents that flow through economic, kinship, religious, and political domains of American life. The book is distinctive in how it combines classic…

  16. Political symbols and political transitions

    Directory of Open Access Journals (Sweden)

    Herrero de Miñón, Miguel

    2006-11-01

    Full Text Available Politics, Law and Psychology are fields that come together in the symbolic. This text takes evidence from those three areas to develop an analysis of political symbols and political transitions. The development of the analysis goes through three stages. The first succinctly describes the concept of transition and its meaning. The second closely examines the notion of the symbol, in terms of its definition, to explain aspects that allow us to understand it, characterise it and make its functions clear. Finally, from the author's experience as a witness and as an actor, I suggest three ways of understanding symbols in the processes of political transition: as symbols of change, as symbols of acknowledgment, and as symbols of support.

  17. Child health and nutrition in Peru within an antipoverty political agenda: a Countdown to 2015 country case study

    OpenAIRE

    Huicho, L.; Segura, E.R.; Huayanay-Espinoza, C.A.; Niño de Guzman, J.; Restrepo-Méndez, M.C.; Tam, Y.; Barros, A.J.D.; Victora, C.G.; Hernández-Peña, P.

    2016-01-01

    Background Peru is an upper-middle-income country with wide social and regional disparities. In recent years, sustained multisectoral antipoverty programmes involving governments, political parties, and civil society have included explicit health and nutrition goals and spending increased sharply. We did a country case study with the aim of documenting Peru's progress in reproductive, maternal, neonatal, and child health from 2000–13, and explored the potential determinants. Methods We examin...

  18. Candidate Gene Study of TRAIL and TRAIL Receptors: Association with Response to Interferon Beta Therapy in Multiple Sclerosis Patients

    Science.gov (United States)

    Órpez-Zafra, Teresa; Pinto-Medel, María Jesús; Oliver-Martos, Begoña; Ortega-Pinazo, Jesús; Arnáiz, Carlos; Guijarro-Castro, Cristina; Varadé, Jezabel; Álvarez-Lafuente, Roberto; Urcelay, Elena; Sánchez-Jiménez, Francisca

    2013-01-01

    TRAIL and TRAIL Receptor genes have been implicated in Multiple Sclerosis pathology as well as in the response to IFN beta therapy. The objective of our study was to evaluate the association of these genes in relation to the age at disease onset (AAO) and to the clinical response upon IFN beta treatment in Spanish MS patients. We carried out a candidate gene study of TRAIL, TRAILR-1, TRAILR-2, TRAILR-3 and TRAILR-4 genes. A total of 54 SNPs were analysed in 509 MS patients under IFN beta treatment, and an additional cohort of 226 MS patients was used to validate the results. Associations of rs1047275 in TRAILR-2 and rs7011559 in TRAILR-4 genes with AAO under an additive model did not withstand Bonferroni correction. In contrast, patients with the TRAILR-1 rs20576-CC genotype showed a better clinical response to IFN beta therapy compared with patients carrying the A-allele (recessive model: p = 8.88×10−4, pc = 0.048, OR = 0.30). This SNP resulted in a non synonymous substitution of Glutamic acid to Alanine in position 228 (E228A), a change previously associated with susceptibility to different cancer types and risk of metastases, suggesting a lack of functionality of TRAILR-1. In order to unravel how this amino acid change in TRAILR-1 would affect to death signal, we performed a molecular modelling with both alleles. Neither TRAIL binding sites in the receptor nor the expression levels of TRAILR-1 in peripheral blood mononuclear cell subsets (monocytes, CD4+ and CD8+ T cells) were modified, suggesting that this SNP may be altering the death signal by some other mechanism. These findings show a role for TRAILR-1 gene variations in the clinical outcome of IFN beta therapy that might have relevance as a biomarker to predict the response to IFN beta in MS. PMID:23658636

  19. A genetic predictive model for canine hip dysplasia: integration of Genome Wide Association Study (GWAS and candidate gene approaches.

    Directory of Open Access Journals (Sweden)

    Nerea Bartolomé

    Full Text Available Canine hip dysplasia is one of the most prevalent developmental orthopedic diseases in dogs worldwide. Unfortunately, the success of eradication programs against this disease based on radiographic diagnosis is low. Adding the use of diagnostic genetic tools to the current phenotype-based approach might be beneficial. The aim of this study was to develop a genetic prognostic test for early diagnosis of hip dysplasia in Labrador Retrievers. To develop our DNA test, 775 Labrador Retrievers were recruited. For each dog, a blood sample and a ventrodorsal hip radiograph were taken. Dogs were divided into two groups according to their FCI hip score: control (A/B and case (D/E. C dogs were not included in the sample. Genetic characterization combining a GWAS and a candidate gene strategy using SNPs allowed a case-control population association study. A mathematical model which included 7 SNPs was developed using logistic regression. The model showed a good accuracy (Area under the ROC curve = 0.85 and was validated in an independent population of 114 dogs. This prognostic genetic test represents a useful tool for choosing the most appropriate therapeutic approach once genetic predisposition to hip dysplasia is known. Therefore, it allows a more individualized management of the disease. It is also applicable during genetic selection processes, since breeders can benefit from the information given by this test as soon as a blood sample can be collected, and act accordingly. In the authors' opinion, a shift towards genomic screening might importantly contribute to reducing canine hip dysplasia in the future. In conclusion, based on genetic and radiographic information from Labrador Retrievers with hip dysplasia, we developed an accurate predictive genetic test for early diagnosis of hip dysplasia in Labrador Retrievers. However, further research is warranted in order to evaluate the validity of this genetic test in other dog breeds.

  20. Boomers versus Millennials: Online Media Influence on Media Performance and Candidate Evaluations

    OpenAIRE

    Terri Towner; Caroline Lego Munoz

    2016-01-01

    Facebook posts, YouTube videos, tweets and wooing political bloggers have become standard practice in marketing political campaigns. Research has demonstrated the effect of new media on a host of politically-related behavior, including political participation, knowledge acquisition, group formation and self-efficacy. Yet, issues related to media trust, media performance and candidate evaluations have not been fully explored. In addition, much of the political marketing research looks exclusiv...

  1. The Impact of Political Conviction on the Relation Between Winning or Losing and Political Dissatisfaction

    OpenAIRE

    Ali Abdelzadeh

    2014-01-01

    Election outcomes, or more specifically belonging to a political minority or majority, have a significant impact on citizens’ attitudes toward the political system and political involvement. This study aims to broaden our understanding in these regards by taking into account the effects of people’s political convictions on the relation between belonging to a political minority or majority and their dissatisfaction with...

  2. The Anabolic Steroid Control Act of 2004: a study in the political economy of drug policy.

    Science.gov (United States)

    Denham, Bryan E

    2006-01-01

    This article examines the processes by which the Anabolic Steroid Control Act of 2004, an act that added steroid precursors such as androstenedione to the list of Schedule III Controlled Substances in the United States, came to pass in both the House of Representatives and the Senate. Grounded theoretically in political economy, the article addresses, in the abstract, how the interplay of political pressures and economic influences stands to affect the actions of public officials, and how "tougher" drug policies-those touted to be more substantive and efficacious than existing regulations-often fail to effect change. The article concludes with implications for those involved in the regulation of anabolic steroids and steroid precursors.

  3. Politics, markets and EU gas supply security. Case studies of the UK and Germany

    Energy Technology Data Exchange (ETDEWEB)

    Kopp, Sandu-Daniel

    2015-03-01

    Publication in the field of social sciences. Sandu-Daniel Kopp investigates whether carbon reduction targets are compatible with market-driven competition in gas (and power) industries, and whether security of supply is compatible with competitive markets. He examines the policy trade-offs which need to be made between the three different elements, and whether these policy judgements should be economically or politically based. The analysis shows the need for a complex set of politically determined options to protect (competitive) markets from price risks and emergency events and demonstrates that this has thus far failed the policy test. Overall, the author argues that the three major elements of EU energy policy are incompatible in important respects and thereby challenges much of the conventional wisdom of EU and Member State policies of the past decade.

  4. Politics, markets and EU gas supply security. Case studies of the UK and Germany

    International Nuclear Information System (INIS)

    Kopp, Sandu-Daniel

    2015-01-01

    Publication in the field of social sciences. Sandu-Daniel Kopp investigates whether carbon reduction targets are compatible with market-driven competition in gas (and power) industries, and whether security of supply is compatible with competitive markets. He examines the policy trade-offs which need to be made between the three different elements, and whether these policy judgements should be economically or politically based. The analysis shows the need for a complex set of politically determined options to protect (competitive) markets from price risks and emergency events and demonstrates that this has thus far failed the policy test. Overall, the author argues that the three major elements of EU energy policy are incompatible in important respects and thereby challenges much of the conventional wisdom of EU and Member State policies of the past decade.

  5. The Politics of Smoking in Federal Buildings: An Executive Order Case Study

    Science.gov (United States)

    Bero, Lisa A.

    2009-01-01

    Executive orders are important presidential tools for health policymaking that are subject to less public scrutiny than are legislation and regulatory rulemaking. President Bill Clinton banned smoking in federal government buildings by executive order in 1997, after the administration of George H. W. Bush had twice considered and abandoned a similar policy. The 1991 and 1993 Bush proposals drew objections from agency heads and labor unions, many coordinated by the tobacco industry. We analyzed internal tobacco industry documents and found that the industry engaged in extensive executive branch lobbying and other political activity surrounding the Clinton smoking ban. Whereas some level of stakeholder politics might have been expected, this policy also featured jockeying among various agencies and the participation of organized labor. PMID:19608948

  6. Nationalism, Mass Politics, and Sport: Cold War Case Studies at Seven Degrees

    Science.gov (United States)

    2008-06-01

    began to develop such as the clan, tribe, and chiefdom. As the societies grew, so did inequality among humans – resulting mainly from the fact... inequality , and chiefs were no longer able to manage quarrels amongst their people. This led to the creation of laws and rules, along with organizations... globalised world of the 21st century,” Third World Quarterly 25:7 (2004): 1326 and 1328. 189 Robert J. Paddick, “Sport and Politics: the (Gross) Anatomy

  7. POLITICAL CHARACTER OF THE SOCIAL ACTIONS IN THE PROCESS OF GLOBALIZATION: A CASE STUDY

    OpenAIRE

    ÇAKIR, Derya; DEMİRHAN, Kamil

    2011-01-01

    Globalization’s attribution of blurring the boundaries is not restricted to the economical and cultural terms. It is also notable for the questions of what is social, what is ecological and what is political. Due to the increase of ecological risks in the global world, some spontaneous social movements have developed to prevent the causes and negative effects of these dangers. Mostly, these movements are seen as in the respect of ecological and social actions. Today it is rather difficu...

  8. POLITICAL COMMUNICATION AND INTERNATIONAL PUBLIC OPINION: A STUDY OF JOKOWI’S INDONESIA

    Directory of Open Access Journals (Sweden)

    Sukawarsini Djelantik

    2016-12-01

    Full Text Available Abstract Joko Widodo (nicknamed Jokowi is Indonesia’s 7th President, elected amid strong popular hope for a new, clean, and effective government. With the support from Indonesia’s Democratic Party for Struggle (PDIP, Jokowi won popular support (53% against Prabowo (47% in the 2014 election. This paper analyzes the effectiveness of Jokowi’s political communication from the general election up to his presidency (2014-2015. Furthermore, the paper discusses Jokowi’s international image through verbal and non-verbal communication. Prabowo, his rival during the election, depicted Jokowi as an Enemy of Islam, a supporter of Christianity, an anti-Muslim, a Zionist, and a mere puppet of the West, in addition to drawing attention to his Chinese descent. Jokowi’s main supporters were volunteers, or “the people’s coalition” as the media called them. Jokowi’s victory was due to the strong support of volunteers who had made effective use of social media (Facebook, Twitter, SMS, and online games. Jokowi’s most significant volunteers were performers and musicians who successfully organized spectacular music concerts for free. These concerts enabled the increase of popular support significantly. After Jokowi became President, people’s expectations were very high. Their expectations were tempered by previous experiences when Indonesia was challenged by corruption perpetrated at various levels of government as well as business interests. This research aims to analyze Jokowi’s political communication performance and international image using the Strength, Weakness, Threat and Opportunity (SWOT analysis. It concludes that Jokowi’s failures were due to poor political communication management. However, his changes in political strategies and management of coalition parties have successfully gained both media and popular support.

  9. Politics and the New African Novel: A Study of the Fiction of Francis Bebey

    OpenAIRE

    W. Curtis Schade

    1980-01-01

    From its inception African fiction has been strongly marked by political themes. In the late 1950's the virulent satire of Mongo Béti and Ferdinand Oyono stated the case against the denigration of African values inherent in all aspects of the colonial system. Their style and message subsequently gave way to novels focusing upon the drama of the transition of power at the moment of Independence. Whether optimistic or disillusioned, many of these novels featured real events and people, often th...

  10. Political terrorism in Southeast Asia and US polity issues : case studies of Thailand and Indonesia

    OpenAIRE

    McDonald, George R.

    1998-01-01

    Approved for public release; distribution is unlimited The end of the Cold War has brought about a decrease in global tensions while regional disorder has increased. In particular, Southeast Asia has become an area of regional economic and political instability. As a result, the possibility of an increase in terrorism, separatist violence, ethnic disputes, and stained regional relations takes on greater significance, both for United States foreign policy and regional Southeast Asian relati...

  11. Theoretical and methodological bases of studying the symbolization of social and political reality in transit societies

    Directory of Open Access Journals (Sweden)

    O. V. Slavina

    2014-10-01

    Full Text Available This article is an attempt to form a methodological foundation to explore the process of symbolic constructioning of reality in the political systems in a state of democratic transition. From the author’s point of view, such transit systems differ with the phenomenal features of transitional type of sign-symbolic context. There are the most significant of them: the confrontation of symbols of old and new, and the formation of public anxiety due to violation of the established values (significant symbols. The result of these processes is the emergence of the conditions for increasing capacity of perception of new symbols (re-symbolization, transmigration of symbolic forms, the appearance of spontaneous symbolic interactions in the community in the form of political protests, rallies, and panic. In this regard, it is necessary to understand the possibilities of the productive management of the collective consciousness in transit period to achieve mental solidarity of concrete society with democratic values. To perform this task, author develops the appropriate tools, which are based on the phenomenological theory, the Schutz’s theory of the constitution of the multiple realities, the philosophy of symbolic forms of E. Cassirer, the theory of social construction of P. Berger and T. Luckmann, as well as Lotman’s semiotic concept. It is concluded that in the collision of alternative symbolic projects of social order it is advisable to resort to controlled symbolization (the production of special symbolic codes of political legitimation. At the same time it is important to understand the mechanisms of auto- symbolization of the society (changing of mass consciousness by virtue of the progressive development of the political culture of people. Careless use of these technologies in the countries with non-consolidated democracy may become a factor of destabilization and formation of the conditions for authoritarian rollback.

  12. Genome-wide association studies and epistasis analyses of candidate genes related to age at menarche and age at natural menopause in a Korean population.

    Science.gov (United States)

    Pyun, Jung-A; Kim, Sunshin; Cho, Nam H; Koh, InSong; Lee, Jong-Young; Shin, Chol; Kwack, KyuBum

    2014-05-01

    The aim of this study was to identify polymorphisms and gene-gene interactions that are significantly associated with age at menarche and age at menopause in a Korean population. A total of 3,452 and 1,827 women participated in studies of age at menarche and age at natural menopause, respectively. Linear regression analyses adjusted for residence area were used to perform genome-wide association studies (GWAS), candidate gene association studies, and interactions between the candidate genes for age at menarche and age at natural menopause. In GWAS, four single nucleotide polymorphisms (SNPs; rs7528241, rs1324329, rs11597068, and rs6495785) were strongly associated with age at natural menopause (lowest P = 9.66 × 10). However, GWAS of age at menarche did not reveal any strong associations. In candidate gene association studies, SNPs with P menopause, there was a significant interaction between intronic SNPs on ADAM metallopeptidase with thrombospondin type I motif 9 (ADAMTS9) and SMAD family member 3 (SMAD3) genes (P = 9.52 × 10). For age at menarche, there were three significant interactions between three intronic SNPs on follicle-stimulating hormone receptor (FSHR) gene and one SNP located at the 3' flanking region of insulin-like growth factor 2 receptor (IGF2R) gene (lowest P = 1.95 × 10). Novel SNPs and synergistic interactions between candidate genes are significantly associated with age at menarche and age at natural menopause in a Korean population.

  13. Framing political messages to fit the audience's regulatory orientation: how to improve the efficacy of the same message content.

    Science.gov (United States)

    Mannetti, Lucia; Brizi, Ambra; Giacomantonio, Mauro; Higgins, E Tory

    2013-01-01

    This research investigates how the impact of persuasive messages in the political domain can be improved when fit is created by subliminally priming recipients' regulatory focus (either promotion or prevention) and by linguistic framing of the message (either strategic approach framing or strategic avoidance framing). Results of two studies show that regulatory fit: a) increases the impact of a political message favoring nuclear energy on implicit attitudes of the target audience (Study 1); and b) induces a more positive evaluation of, and intentions to vote for, the political candidate who is delivering a message concerning immigration policies (Study 2).

  14. Citizen Candidates Under Uncertainty

    OpenAIRE

    Eguia, Jon X.

    2005-01-01

    In this paper we make two contributions to the growing literature on "citizen-candidate" models of representative democracy. First, we add uncertainty about the total vote count. We show that in a society with a large electorate, where the outcome of the election is uncertain and where winning candidates receive a large reward from holding office, there will be a two-candidate equilibrium and no equilibria with a single candidate. Second, we introduce a new concept of equilibrium, which we te...

  15. Corrosion susceptibility study of candidate pin materials for ALTC (active lithium/thionyl chloride) batteries. [Active lithium/thionyl chloride

    Energy Technology Data Exchange (ETDEWEB)

    Bovard, F.S.; Cieslak, W.R.

    1987-09-01

    (ALTC = active lithium/thionyl chloride.) We have investigated the corrosion susceptibilities of eight alternate battery pin materials in 1.5M LiAlCl/sub 4//SOCl/sub 2/ electrolyte using ampule exposure and electrochemical tests. The thermal expansion coefficients of these candidate materials are expected to match Sandia-developed Li-corrosion resistant glasses. The corrosion resistances of the candidate materials, which included three stainless steels (15-5 PH, 17-4 PH, and 446), three Fe-Ni glass sealing alloys (Kovar, Alloy 52, and Niromet 426), a Ni-based alloy (Hastelloy B-2) and a zirconium-based alloy (Zircaloy), were compared to the reference materials Ni and 316L SS. All of the candidate materials showed some evidence of corrosion and, therefore, did not perform as well as the reference materials. The Hastelloy B-2 and Zircaloy are clearly unacceptable materials for this application. Of the remaining alternate materials, the 446 SS and Alloy 52 are the most promising candidates.

  16. Teacher Self-Efficacy Perceptions, Learning Oriented Motivation, Lifelong Learning Tendencies of Candidate Teachers: A Modeling Study

    Science.gov (United States)

    Akyol, Bertan

    2016-01-01

    Problem Statement: While the concept of professional self-efficacy corresponds to the power and belief employees feel related to tasks they are performing, motivation can be defined as the internal energy which shapes work related behaviors of employees positively. Although there are many features that teachers and candidate teachers must have,…

  17. Theoretical study of sensitizer candidates for dye-sensitized solar cells: peripheral substituted dizinc pyrazinoporphyrazine-phthalocyanine complexes.

    Science.gov (United States)

    Zarate, Ximena; Schott, Eduardo; Gomez, Tatiana; Arratia-Pérez, Ramiro

    2013-01-17

    We have carried out a theoretical study of the geometrical and electronic structures of a family of planar dimers constituted by zinc(II) pyrazinoporphyrazine and zinc(II) phthalocyanine with peripheral electron-donating and electron-withdrawing substituents R [where R = -OH (1), -C(CH(3))(3) (2), -CH(3) (3), -C(6)H(5) (4), -H (5), -CO(2)H (7), -NO(2) (7), and -PO(3)H(2) (8)]. The complexes are connected by varying the bridge (B) ligand, where, in 1-9, B is -CH= and, in 10-12, B is -N=, -O-, and -S-, respectively. The -CO(2)H group was included in complexes identified as 9-12. This was done because of the known properties of this group in acting as an anchor to adsorb a dye onto a semiconductor oxide. The aim of this work was to provide a useful theoretical basis for the design and screening of new potential dye candidates to be used in these devices, based on the properties of the dyes suitable for their good performance in solar cells, such as frontier molecular orbital spatial distributions; charge-separated states in the electronic transitions in the visible region of the spectrum; and importantly, the energy diagram of the frontier MOs of these dyes and the conduction band (CB) of the semiconductor, where the LUMO energy levels that are above of the CB suggest which dyes are capable of electron injection into TiO(2). In this sense, it is expected that complexes 1-5 and 9-12 should be very promising dyes to act as sensitizers. Finally, a linear correlation was found between the HOMO and LUMO energies of all of the systems and the Hammett constants, where these molecular orbitals become more stable when R is more electron-withdrawing.

  18. Political Campaigns Music Video As A Strategy For Forming Perceptions

    Directory of Open Access Journals (Sweden)

    Winny Gunarti Widya Wardani

    2017-11-01

    Full Text Available Political campaigns music video not only acts as a medium of information but has the potential to form perceptions in an entertaining way. As a media campaign the music video which broadcast through television and social media are considered as a more persuasive strategy towards the target audience. This study discusses the political campaigns music video of candidates for Jakartas regional head of Gerindra Party during the Election of Jakarta Regional Head 2017 which features three different music video styles namely pop rap and religious. Qualitatively visual modalities and visual perception approach are used to analyze the formation of perceptions in the political campaigns music video. As a result music video can effectively build perceptions through elements of text image and music as an informative and entertaining campaign spectacle.

  19. The Effects of Print Comparative Political Advertising on Political Decision-Making and Participation.

    Science.gov (United States)

    Pinkleton, Bruce E.

    1998-01-01

    Examines intended and unintended effects of print comparative political advertising on political decision making, voting preferences, and situational election involvement among a sample of communication and business undergraduate students. Suggests that comparative advertising reduces targeted-candidate voting preferences while avoiding most forms…

  20. Political philosophy, ethnology, and time: a study of the notion of historical handicap

    Directory of Open Access Journals (Sweden)

    João Feres Jr

    2002-06-01

    Full Text Available This article starts by identifying the crucial importance of the notion of historical handicap for the present-day social sciences of Latin America. Such notion is not an original invention made by Latinamericanists. On the contrary, I demonstrate that the genealogy of the notion of historical handicap must be sought in the tradition of Western political philosophy. Such genealogy must take into account the way it was integrated into ethnological descriptions. When and how did the Other become the backward, the primitive? While this relation was secondary for ancient Greek thought, theories of historical development became the main source of ethnological categories in the modern era. Interestingly enough, this modern synthesis suited the practical purpose of justifying two successive waves of European imperialistic: the era of discoveries, and 19th century colonialism. The article concludes by raising questions about the present role and application of the social sciences.Esse artigo começa por identificar o papel central da noção de incapacidade histórica para a literatura de Latin American studies produzida no pós-guerra. Tal noção não foi criada pelos Latinoamericanistas contemporâneos. É possível identificar o embrião da noção de incapacidade histórica nos mitos primitivistas da antiguidade clássica e, a partir daí, examinar as várias maneiras com que ela foi recebida e rearticulada pela tradição filosófica ocidental. Esse estudo é feito tendo em vista a incorporação da noção de incapacidade histórica a teorias etnológicas. Quando e como o "outro" passou a ser visto como o "atrasado", o "primitivo"? Se na antiguidade clássica essa identificação era incompleta, na era moderna teorias de desenvolvimento histórico se tornaram a fonte principal de categorias etnológicas. É importante notar que a síntese moderna dessas teorias também serviram para justificar as aventuras imperialistas Européias: a era dos

  1. Political ecology

    International Nuclear Information System (INIS)

    Strohm, H.

    1979-01-01

    Using facts and examples, this didactically structures textbook gives an insight into the extent and consequences of the damage to the environment, with the subjects - fundamentals of ecology; - population and food problems; - the energy problem; - economic growth; scarcity of resources, recycling; - ground, water, and air pollution, - city and traffic problems; - work protection and medical care; - political alternatives and 'soft technologies'. The analysis of the political and economic reasons is combined with social and technical alternatives from which demands to be made and measures to be taken can be derived for individuals, citizens' interest groups, political groups and trade unions. Teaching models intend to help teachers to work on specific problems of ecology. (orig.) [de

  2. Political priorities

    DEFF Research Database (Denmark)

    Ren, Jingzheng

    2016-01-01

    …THE POLITICAL LEADERS of the local government of Chongqing, China, vigorously promote a low-carbon economy and sustainable development to mitigate environmental pollution. Accordingly, research grants focused on this issue were supported by the government, and our group obtained a grant for a pr...... for a project about industrial park planning and design.…In my view, political priorities based on correct decision-making and market requirements are beneficial for researchers.......…THE POLITICAL LEADERS of the local government of Chongqing, China, vigorously promote a low-carbon economy and sustainable development to mitigate environmental pollution. Accordingly, research grants focused on this issue were supported by the government, and our group obtained a grant...

  3. Political CSR

    DEFF Research Database (Denmark)

    Jeppesen, Søren; Morsing, Mette

    We engage a discussion of political CSR in SMEs in an African context. Based on critical observations on Western MNC CSR action in emerging economies that holds counterproductive implications for social development, political economists have argued that business profit far more than society...... development in local African communities. Our findings extend political CSR research by directing attention to how the corporate influence in developing economies does not only emerge from MNCs but is also established and retained by SMEs CSR work....... in developing economies from CSR. In this paper we argue that local SMEs CSR work have strong influence in developing economies, that also includes counterproductive influence for social development. Based on empirical findings from African countries, we conceptualize how CSR in African SMEs differ from...

  4. Does refining the phenotype improve replication rates? A review and replication of candidate gene studies on Major Depressive Disorder and Chronic Major Depressive Disorder.

    Science.gov (United States)

    Luo, Xiaochen; Stavrakakis, Nikolaos; Penninx, Brenda W; Bosker, Fokko J; Nolen, Willem A; Boomsma, Dorret I; de Geus, Eco J; Smit, Johan H; Snieder, Harold; Nolte, Ilja M; Hartman, Catharina A

    2016-03-01

    Replication has been poor for previously reported candidate genes involved in Major Depressive Disorder (MDD). One possible reason is phenotypic and genetic heterogeneity. The present study replicated genetic associations with MDD as defined in DSM-IV and with a more narrowly defined MDD subtype with a chronic and severe course. We first conducted a systematic review of genetic association studies on MDD published between September 2007 and June 2012 to identify all reported candidate genes. Genetic associations were then tested for all identified single nucleotide polymorphisms (SNPs) and the entire genes using data from the GAIN genome-wide association study (MDD: n = 1,352; chronic MDD subsample: n = 225; controls: n =  1,649). The 1,000 Genomes database was used as reference for imputation. From 157 studies identified inthe literature, 81 studies reported significant associations with MDD, involving 245 polymorphisms in 97 candidate genes, from which we were able to investigate 185 SNPs in 89 genes. We replicated nine candidate SNPs in eight genes for MDD and six in five genes for chronic MDD. However, these were not more than expected by chance. At gene level, we replicated 18 genes for MDD and 17 genes for chronic MDD, both significantly more than expected by chance. We showed that replication rates were improved for MDD compared to a previous, highly similar, replication study based on studies published before 2007. Effect sizes of the SNPs and replication rates of the candidate genes were improved in the chronic subsample compared to the full sample. Nonetheless, replication rates were still poor. © 2015 Wiley Periodicals, Inc.

  5. Determination of Perceptions of the Teacher Candidates Studying in the Computer and Instructional Technology Department towards Human-Computer Interaction and Related Basic Concepts

    Science.gov (United States)

    Kiyici, Mubin

    2011-01-01

    HCI is a field which has an increasing popularity by virtue of the spread of the computers and internet and gradually contributes to the production of the user-friendlier software and hardware with the contribution of the scientists from different disciplines. Teacher candidates studying at the computer and instructional technologies department…

  6. An International Standard for specifying the minimum potency of anti-D blood-grouping reagents: evaluation of a candidate preparation in an international collaborative study

    NARCIS (Netherlands)

    Thorpe, S. J.; Fox, B.; Heath, A. B.; Scott, M.; de Haas, M.; Kochman, S.; Padilla, A.

    2006-01-01

    The aim of this study was to evaluate a lyophilized monoclonal immunoglobulin M (IgM) anti-D preparation for use as an International Standard to specify a recommended minimum acceptable potency of anti-D blood-grouping reagents. The candidate International Standard (99/836) for specifying the

  7. Hyper-Plurality of Candidates, Effectiveness of Democratic Representation and Regulation of Candidate Entry in India

    OpenAIRE

    Kaushik, Bhattacharya; Subrata K, Mitra

    2013-01-01

    The presence of large number of candidates in Indian elections had often evoked extremely strong policy recommendations from different expert groups. The major policy tool to control candidate entry in India had, however, been electoral deposit. Using panel data on elections in different states and UTs, our study estimates the impact of electoral deposit on candidate entry. Results suggest that increase in deposit had a substantial short-term negative impact on candidate entry. The candidate ...

  8. A Political Campaign Strategy and Campaign Theme : How to Win a Political Campaign

    OpenAIRE

    河村, 直幸; Kawamura, Naoyuki

    2004-01-01

    The aim of this research paper is to introduce a political campaign strategy. A political campaign should do on a scientific system and needs effective strategy. Before political campaign begin, a candidate and its campaigner needs to analyze election district and sample voter opinion. An election campaign needs campaign theme. The creation of campaign theme needs careful and elaborate planning. A style of campaign varies according to incumbent or challenger. The developing of an effective po...

  9. Data politics

    OpenAIRE

    Bigo, Didier; Isin, Engin; Ruppert, Evelyn

    2017-01-01

    The commentary raises political questions about the ways in which data has been constituted as an object vested withcertain powers, influence, and rationalities.We place the emergence and transformation of professional practices such as‘data science’, ‘data journalism’, ‘data brokerage’, ‘data mining’, ‘data storage’, and ‘data analysis’ as part of the reconfigurationof a series of fields of power and knowledge in the public and private accumulation of data. Data politics asksquestions about ...

  10. 'Grounded' Politics

    DEFF Research Database (Denmark)

    Schmidt, Garbi

    2012-01-01

    A prominent strand within current migration research argues that, to understand the participation of immigrants in their host societies, we must focus on their incorporation into the cities in which they settle. This article narrows the perspective further by focusing on the role that immigrants...... play within one particular neighbourhood: Nørrebro in the Danish capital, Copenhagen. The article introduces the concept of grounded politics to analyse how groups of Muslim immigrants in Nørrebro use the space, relationships and history of the neighbourhood for identity political statements...

  11. Political regimes, political ideology, and self-rated health in Europe : a multilevel analysis

    NARCIS (Netherlands)

    Huijts, T.; Perkins, J.M; Subramanian, S.V.

    2010-01-01

    Background: Studies on political ideology and health have found associations between individual ideology and health as well as between ecological measures of political ideology and health. Individual ideology and aggregate measures such as political regimes, however, were never examined

  12. Genetic association study of selected candidate genes (ApoB, LPL, Leptin and telomere length in obese and hypertensive individuals

    Directory of Open Access Journals (Sweden)

    Saini Divyalakshmi

    2009-09-01

    Full Text Available Abstract Background A genetic study was carried out among obese and hypertensive individuals from India to assess allelic association, if any, at three candidate loci: Apolipoprotein B (ApoB minisatellite and two tetranucleotide repeat loci; LPL (Lipoprotein lipase and Leptin. Attempt has also been made to find out whether telomere length attrition is associated with hypertension and obese individuals. Methods Venous blood samples were collected from 37 normal, 35 obese and 47 hypertensive individuals. Genomic DNA was extracted from peripheral blood mononuclear cells (PBMC and PCR amplifications were achieved using locus specific primers. Genotyping of ApoB minisatellite was performed using 4% polyacrylamide gel electrophoresis (PAGE followed by silver staining, whereas LPL and Leptin loci were genotyped using ALF Express™ DNA sequencer. Telomere length was determined using a recently developed real time based quantitative PCR, where the relative telomere length was determined by calculating the relative ratio of telomere (T and single copy gene (S PCR products which is expressed as T/S ratio. Results All the three loci are highly polymorphic, display high heterozygosity and conform to Hardy-Weinberg's equilibrium expectations. ApoB minisatellite displayed 14 alleles, whereas LPL and Leptin tetranucleotide loci were having 9 and 17 alleles, respectively. Interestingly two new alleles (9 and 11 repeats were detected at ApoB locus for the first time. The alleles at Leptin locus were classified as Class I (lower alleles: 149-200 bp and Class II alleles (higher alleles: >217 bp. Higher alleles at ApoB (>39 repeats, predominant allele 9 at LPL and alleles 164 bp and 224 bp at Leptin loci have shown allelic association with hypertensive individuals. After adjusting the influence of age and gender, the analysis of co-variance (ANCOVA revealed the relative telomere length (T/S ratio in hypertensive individuals to be (1.01 ± 0.021, which was

  13. Multi-institutional Study of Outcomes After Pediatric Heart Transplantation: Candidate Gene Polymorphism Analysis of ABCC2

    Science.gov (United States)

    Burckart, Gilbert J.; Figg, William D.; Brooks, Maria M.; Green, Dionna J.; Troutman, Sarah M.; Ferrell, Robert; Chinnock, Richard; Canter, Charles; Addonizio, Linda; Bernstein, Daniel; Kirklin, James K.; Naftel, David; Price, Douglas K.; Sissung, Tristan M.; Girnita, Diana M.; Zeevi, Adriana; Webber, Steven A.

    2014-01-01

    OBJECTIVES Earlier studies have indicated that the pharmacokinetics of mycophenolic acid (MPA) is influenced by polymorphisms of ABCC2, which encodes for the membrane transporter MRP2. The ABCC2 rs717620 A allele has been associated with enterohepatic recirculation of MPA, and our previous work had correlated the discontinuance of MPA with this allele in pediatric heart transplant patients. Therefore, we hypothesized that the ABCC2 rs717620 A allele would be associated with poorer outcomes including rejection with hemodynamic compromise (RHC), graft failure, and death in the pediatric heart transplant (PHTx) population receiving MPA. METHODS PHTx recipients from 6 institutions in the Pediatric Heart Transplantation Study (PHTS) from the period of 1993–2009, receiving MPA therapy, were genotyped for ABCC2 rs717620. Genotyping was accomplished by direct sequencing. Demographic and outcome data were limited to the data routinely collected as part of the PHTS and included RHC and mortality. RESULTS Two hundred ninety patients were identified who received MPA at some point post transplantation, of which 200 carried the GG genotype, 81 carried the AG genotype, and 9 carried the AA genotype. Follow-up time after transplantation was 6 years. RHC occurred in 76 patients and 18 patients died. In the 281 patients followed up more than 1 year, late RHC (>1 year post transplantation) occurred in 42 patients. While both RHC and late RHC were associated with the ABCC2 rs717620 GG genotype (hazard ratios: 1.80 and 4.57, respectively, p<0.05) in all patients, this association was not significant in PHTx patients receiving only MPA as the antiproliferative agent from the time of transplant (n=142). CONCLUSIONS ABCC2 rs717620 polymorphisms varied within racial groups. As a candidate gene assessment, the ABCC2 rs717620 AG and AA genotypes may be associated with improved, rather than poorer, RHC in PHTx patients receiving MPA therapy. ABCC2 rs717620 polymorphisms should be included

  14. Computer-aided discovery of debris disk candidates: A case study using the Wide-Field Infrared Survey Explorer (WISE) catalog

    Science.gov (United States)

    Nguyen, T.; Pankratius, V.; Eckman, L.; Seager, S.

    2018-04-01

    Debris disks around stars other than the Sun have received significant attention in studies of exoplanets, specifically exoplanetary system formation. Since debris disks are major sources of infrared emissions, infrared survey data such as the Wide-Field Infrared Survey (WISE) catalog potentially harbors numerous debris disk candidates. However, it is currently challenging to perform disk candidate searches for over 747 million sources in the WISE catalog due to the high probability of false positives caused by interstellar matter, galaxies, and other background artifacts. Crowdsourcing techniques have thus started to harness citizen scientists for debris disk identification since humans can be easily trained to distinguish between desired artifacts and irrelevant noises. With a limited number of citizen scientists, however, increasing data volumes from large surveys will inevitably lead to analysis bottlenecks. To overcome this scalability problem and push the current limits of automated debris disk candidate identification, we present a novel approach that uses citizen science results as a seed to train machine learning based classification. In this paper, we detail a case study with a computer-aided discovery pipeline demonstrating such feasibility based on WISE catalog data and NASA's Disk Detective project. Our approach of debris disk candidates classification was shown to be robust under a wide range of image quality and features. Our hybrid approach of citizen science with algorithmic scalability can facilitate big data processing for future detections as envisioned in future missions such as the Transiting Exoplanet Survey Satellite (TESS) and the Wide-Field Infrared Survey Telescope (WFIRST).

  15. A study to determine the association between tobacco smoking habit and oral candidal infection in median rhomboid glossitis by cytologic and histopathologic methods

    Directory of Open Access Journals (Sweden)

    Anitha Bojan

    2012-01-01

    Full Text Available Objectives: To determine the association, if any, between tobacco smoking and candidal infection in median rhomboid glossitis (MRG and to histopathologically evaluate the presence of dysplastic changes in it. Study design: Hospital-based study consisting of 100 subjects who satisfied the clinical criteria of MRG- Smears and swabs were collected to ascertain the presence of Candida and sub-typing was done utilizing the CHROMagar technique. Biopsy and histopathological examination was done to determine the presence or absence of dysplasia of the lesional tissue. Results: All the subjects were male and had the habit of smoking- Smears and swabs taken from glossal lesion of 60 subjects′ showed 100% candidal positivity. Tissue section from 31 subjects showed histological picture consistent with MRG and 23 (74% showed dysplastic changes. Conclusion: MRG is a Candida-associated lesion and the tobacco-smoking habit in our cohort may play an important role in increasing the candidal colonization. As some of our cases exhibited mild epithelial dysplasia, both candidal colonization and smoking habits may have contributed to the dysplastic changes.

  16. Understanding political market orientation

    DEFF Research Database (Denmark)

    Ormrod, Robert P.; Henneberg, Stephan C.

    influences of such behavior. The study includes structural equation modeling to investigate several propositions. While the results show that political parties need to focus on several different aspects of market-oriented behavior, especially using an internal and external orientation as cultural antecedents......This article develops a conceptual framework and measurement model of political market orientation that consists of attitudinal and behavioural constructs. The article reports on perceived relationships among different behavioral aspects of political market orientation and the attitudinal......, a more surprising result is the inconclusive effect of a voter orientation on market-oriented behaviours. The article discusses the findings in the context of the existing literature in political marketing and commercial market orientation....

  17. The Politics of Universalism

    DEFF Research Database (Denmark)

    Simonsen, Karen-Margrethe

    2013-01-01

    ’ of globalization. Historically speaking, human rights are closely connected with globalization, but at the same time, they raise a question about the foundation of globalization: is there a universal community or only economic and political power-relations? The article argues that the political use of human rights...... discourses is split down the middle: it serves both as a critique of power and as an extension of power, and the disclosure of this split helps us understand the inner politics of human rights. The article discusses the trial in Valladolid in 1550 when the rights of the barbarian Indians of America were put......This article investigates the political function of human rights in the 16th Century in Spain just after the conquest of America. It claims that the study of this period of early globalization is relevant for the understanding of the function of human rights discourses to day, at the ‘end...

  18. [Medical politics. Graffiti].

    Science.gov (United States)

    Fugelli, P

    1991-03-20

    If doctors want to play a role in future health promotion, they have to leave their citadel, and come closer to life and society. Modern preventive medicine cannot be dissociated from basic political, cultural and religious values and processes. Genetic counseling and engineering, influencing lifestyle, community intervention and changing the health culture among patients and doctors all require ethical and political competence rather than traditional medical skills. The author advocates the development of a new discipline, medical politics, with two major commitments: -To define basic health rights -To study the public health consequences of political systems and decisions. In a polemic and provocative style the article enlightens the potentials and dangers associated with an expanded concept of preventive medicine.

  19. Politics 3

    Science.gov (United States)

    Maslow, Abraham

    1977-01-01

    This article expresses some last thoughts from Abraham Maslow on his vision of humanistic psychology. He suggests that the two main problems of creating the good person and the good society are interwoven inextricably. He gives some social and political mechanisms which would enhance desirable personal growth and considers the main tasks of…

  20. Political bugs.

    Science.gov (United States)

    Lucas, W. R.

    1972-01-01

    Certain decisions, problems, and successes are selected to recall the great impact of the 1950s on the history of rocketry, and particularly the inauguration of the space age. In reviewing the history of the Redstone, Juno, and Jupiter, some of the largest stepping stones to space, problems stand out in three areas: technical or engineering, management, and political.