WorldWideScience

Sample records for policy process edited

  1. Energy Policy. Highlights. 2013 Edition

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-07-01

    Energy Policy Highlights showcases recent developments in energy policies among all 28 IEA member countries. Each contribution underscores the changing nature of both global and domestic energy challenges, as well as the commonality of energy concerns among member countries. The policies highlighted in this publication identify an urgent need to reduce greenhouse gas (GHG) emissions as a clear policy objective. Electricity, enhancing energy efficiency and increasing the share of renewables in the energy mix in a cost effective manner are likewise areas of common focus. On the end-user side, increasing public awareness of domestic energy policies through improved transparency and engagement is an important facet of policy support among IEA member countries. The successful implementation of policies and other initiatives benefitted from efforts to inform the public.

  2. Statistical Policy Working Paper 25. Data Editing Workshop and Exposition

    Science.gov (United States)

    1996-12-01

    Statistical Policy Working Paper 25 is the written record of the Data Editing Workshop and Exposition held March 22, 1996, at the Bureau of Labor Statistics (BLS) Conference and Training Center. The program consisted of 44 oral presentations and 19 s...

  3. Gene-Editing: Interpretation of Current Law and Legal Policy

    OpenAIRE

    Kim, Na-Kyoung

    2017-01-01

    ABSTRACT With the development of the third-generation gene scissors, CRISPR-Cas9, concerns are being raised about ethical and social repercussions of the new gene-editing technology. In this situation, this article explores the legislation and interpretation of the positive laws in South Korea. The BioAct does not specify and regulate 'gene editing' itself. However, assuming that genetic editing is used in the process of research and treatment, we can look to the specific details of the regul...

  4. Mining and minerals policy: 1976 bicentennial edition

    Energy Technology Data Exchange (ETDEWEB)

    1976-07-01

    The report is organized into three basic parts. The first part, the Executive Summary, provides a brief description of the major topics and lists the issues and recommendations. The report then is divided into two sections. Section I, Summary, is comprised of three chapters: Increased Energy Security; Metals and Nonmetallic Minerals; and Trends and Events. Section II, Issues in Energy and Minerals Policy, is comprised of seven chapters: Federal Leasing; The Federal Role in Reducing the Fiscal Impacts of Energy Development; Availability of Federal Lands for Mineral Exploration and Development; Environmental Issues and the Mineral Industry; Developments in International Minerals Trade and Investment; Ocean Mining; and The Development of New Tools for Energy and Minerals Policy Analysis. (MCW)

  5. Gene-Editing: Interpretation of Current Law and Legal Policy.

    Science.gov (United States)

    Kim, Na-Kyoung

    2017-09-01

    With the development of the third-generation gene scissors, CRISPR-Cas9, concerns are being raised about ethical and social repercussions of the new gene-editing technology. In this situation, this article explores the legislation and interpretation of the positive laws in South Korea. The BioAct does not specify and regulate 'gene editing' itself. However, assuming that genetic editing is used in the process of research and treatment, we can look to the specific details of the regulations for research on humans as well as gene therapy research in order to see how genetic editing is regulated under the BioAct. BioAct differentiates the regulation between (born) humans and embryos etc. and the regulation differ entirely in the manner and scope. Moreover, due to the fact that gene therapy products are regarded as drugs, they fall under different regulations. The Korean Pharmacopoeia Act put stringent sanctions on clinical trials for gene therapy products and the official Notification "Approval and Examination Regulations for Biological Products, etc." by Food and Drug Safety Administration may be applied to gene editing for gene therapy purposes.

  6. Safety, Security, and Policy Considerations for Plant Genome Editing.

    Science.gov (United States)

    Wolt, Jeffrey D

    2017-01-01

    Genome editing with engineered nucleases (GEEN) is increasingly used as a tool for gene discovery and trait development in crops through generation of targeted changes in endogenous genes. The development of the CRISPR-Cas9 system (clustered regularly interspaced short palindromic repeats with associated Cas9 protein), in particular, has enabled widespread use of genome editing. Research to date has not comprehensively addressed genome-editing specificity and off-target mismatches that may result in unintended changes within plant genomes or the potential for gene drive initiation. Governance and regulatory considerations for bioengineered crops derived from using GEEN will require greater clarity as to target specificity, the potential for mismatched edits, unanticipated downstream effects of off-target mutations, and assurance that genome reagents do not occur in finished products. Since governance and regulatory decision making involves robust standards of evidence extending from the laboratory to the postcommercial marketplace, developers of genome-edited crops must anticipate significant engagement and investment to address questions of regulators and civil society. © 2017 Elsevier Inc. All rights reserved.

  7. Meat and Poultry Processing. Teacher Edition.

    Science.gov (United States)

    Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

    This curriculum guide contains instructional materials for a program that provides students with job skills in meat and poultry processing. The curriculum consists of 10 units that cover the following material: orientation to meat and poultry processing; maintaining plant facilities; equipment and equipment maintenance; purchasing livestock for…

  8. Sport in the Sociocultural Process. Second Edition.

    Science.gov (United States)

    Hart, Marie

    This anthology is an introduction to the sociocultural study of sport for those in physical education, sociology, anthropology, or any other study of human behavior in the social process. Part I provides a cultural framework, a series of definitions, and some understandings of the cultural setting of sport in American society as an orientation to…

  9. Surviving Your Dissertation: A Comprehensive Guide to Content and Process. Third Edition

    Science.gov (United States)

    Rudestam, Kjell Erik; Newton, Rae R.

    2007-01-01

    Like the previous editions of this bestselling text, "Surviving Your Dissertation: A Comprehensive Guide to Content and Process, Third Edition" offers readers guidance that other dissertation guides often miss, from ways to improve one's writing, to identifying one's learning preferences, to dealing with emotional blocks. Using examples from a…

  10. Ethnosocial processes and ethnonational policy

    Directory of Open Access Journals (Sweden)

    Yuri V. Popkov

    2016-07-01

    Full Text Available Article arises the issues of ethnicity in context of globalization, as well as axiological dominants of collective public consciousness, trends of Siberian people ethnosocial evolution, problems of actual national policy of government in Russia.

  11. Edit distance for marked point processes revisited: An implementation by binary integer programming.

    Science.gov (United States)

    Hirata, Yoshito; Aihara, Kazuyuki

    2015-12-01

    We implement the edit distance for marked point processes [Suzuki et al., Int. J. Bifurcation Chaos 20, 3699-3708 (2010)] as a binary integer program. Compared with the previous implementation using minimum cost perfect matching, the proposed implementation has two advantages: first, by using the proposed implementation, we can apply a wide variety of software and hardware, even spin glasses and coherent ising machines, to calculate the edit distance for marked point processes; second, the proposed implementation runs faster than the previous implementation when the difference between the numbers of events in two time windows for a marked point process is large.

  12. Diaspora Lobbies and the US Government: Convergence and Divergence in Making Foreign Policy, edited by Josh DeWind and Renata Segura, Social Science Research Council and New York University Press, 2014

    Directory of Open Access Journals (Sweden)

    Thomas Ambrosio

    2015-07-01

    Full Text Available Ethnic groups in the United States have long advocated on behalf of their countries of origin and their interests. Our understanding of ethnic group influence on the American foreign policy process, however, remains tentative. Diaspora Lobbies and the US Government, a collection of essays edited by Josh DeWind and Renata Segura, makes a fresh contribution to this area of study through its focus on policy convergence/divergence between the US government and ethnic interest groups.

  13. Simulating Policy Processes through Electronic Mail.

    Science.gov (United States)

    Flynn, John P.

    1987-01-01

    Focuses on the use of electronic mail for teaching and learning about social welfare policy processes and compares electronic mail as a simulation medium to more structured computer applications. (Author)

  14. An Automated Policy Refinement Process Supported by Expert Knowledge

    OpenAIRE

    Rochaeli, Taufiq

    2009-01-01

    In a policy-based system management, a policy refinement process is required to translate abstract policies, which are specified by human, into enforceable policies, which are enforced by machine. However, a manual policy refinement process imposes some problems. The first problem is that it requires expert knowledge to perform the policy refinement process. The second problem is that refining policies for complex systems is a tedious task. Manual refinement process may cause some negative co...

  15. Transforming Government's Policy-making Processes

    Directory of Open Access Journals (Sweden)

    Paul Johnston

    2010-09-01

    Full Text Available We have seen a lot of very welcome progress in terms of making it easier for citizens to input their views into government policy-making processes. However, governments and citizens are now in a similar situation – after a burst of initial enthusiasm, they are not sure what to do next. Governments have struggled to get the mass participation they would like and where significant participation has occurred, have had difficulty integrating it effectively into existing decision-making processes. Citizens have been unsure what to make of this new apparent openness and where they have engaged, have found it hard to know what difference their input made. The solution is to focus on using technology to make existing policy processes more transparent and more participative rather than creating separate e-participation initiatives. The challenge for governments is to open up the whole of the policy process and be prepared to flag up very clearly and explicitly the difference citizen input made. The challenge for e-democracy advocates is to convince policymakers that their ideas can improve the existing policy process rather than simply generating more inputs into it.

  16. Social Science in Government: The Role of Policy Researchers. New Edition.

    Science.gov (United States)

    Nathan, Richard P.

    This substantially updated version of a book first published in 1988 tells the story of welfare reform in the United States over the past three decades, with an emphasis on contributions made by social scientists. This edition contains five new chapters with new case material to show how social science principles can be used in U.S. government. In…

  17. Educating Emergent Bilinguals: Policies, Programs, and Practices for English Learners. Second Edition. Language and Literacy Series

    Science.gov (United States)

    Garcia, Ofelia; Kleifgen, Jo Anne

    2018-01-01

    Now available in a revised and expanded edition, this accessible guide introduces readers to the issues and controversies surrounding the education of language minority students in the United States. What makes this book a perennial favorite are the succinct descriptions of alternative practices for transforming our schools and students' futures,…

  18. Human Germline Genome Editing.

    Science.gov (United States)

    Ormond, Kelly E; Mortlock, Douglas P; Scholes, Derek T; Bombard, Yvonne; Brody, Lawrence C; Faucett, W Andrew; Garrison, Nanibaa' A; Hercher, Laura; Isasi, Rosario; Middleton, Anna; Musunuru, Kiran; Shriner, Daniel; Virani, Alice; Young, Caroline E

    2017-08-03

    With CRISPR/Cas9 and other genome-editing technologies, successful somatic and germline genome editing are becoming feasible. To respond, an American Society of Human Genetics (ASHG) workgroup developed this position statement, which was approved by the ASHG Board in March 2017. The workgroup included representatives from the UK Association of Genetic Nurses and Counsellors, Canadian Association of Genetic Counsellors, International Genetic Epidemiology Society, and US National Society of Genetic Counselors. These groups, as well as the American Society for Reproductive Medicine, Asia Pacific Society of Human Genetics, British Society for Genetic Medicine, Human Genetics Society of Australasia, Professional Society of Genetic Counselors in Asia, and Southern African Society for Human Genetics, endorsed the final statement. The statement includes the following positions. (1) At this time, given the nature and number of unanswered scientific, ethical, and policy questions, it is inappropriate to perform germline gene editing that culminates in human pregnancy. (2) Currently, there is no reason to prohibit in vitro germline genome editing on human embryos and gametes, with appropriate oversight and consent from donors, to facilitate research on the possible future clinical applications of gene editing. There should be no prohibition on making public funds available to support this research. (3) Future clinical application of human germline genome editing should not proceed unless, at a minimum, there is (a) a compelling medical rationale, (b) an evidence base that supports its clinical use, (c) an ethical justification, and (d) a transparent public process to solicit and incorporate stakeholder input. Copyright © 2017 American Society of Human Genetics. All rights reserved.

  19. Editorial policies and background in editing Macedonian Medical Review and BANTAO journal.

    Science.gov (United States)

    Spasovski, Goce

    2014-01-01

    Even in as small a country as R. Macedonia with limited resources allocated for science, there are many journals trying to establish good editorial practices and policies in publishing the scientific work achieved. Among the currently existing medical journals Macedonian Medical Review (MMR), ISSN 0025-1097, deserves to be elaborated as the oldest journal with continuous publication since its first appearance as the journal of the Macedonian Medical Association (MMA). Since its first issue, published in 1946, there has been an opus of some 4500 peer-reviewed published papers in more than 210 issues and some 80 supplements from various congresses and meetings. In this regard, great respect should be paid not only to the editorial boards, but also to the collaborators who have contributed to its successful continuity in all previous years. In line with the needs for further development of the journal and possibilities for access to world databases, the Editorial Board of MMR has made every effort to improve and modernize its work as well as the technical quality of the journal. Hence, MMA has signed a contract with De Gruyter Open as leading publisher of Open Access academic content for further improvement and promotion of the journal and facilitation of the Medline application, so we do hope for the further success of the journal. BANTAO Journal is published on behalf of the Balkan Cities Association of Nephrology, Dialysis, Transplantation and Artificial Organs (BANTAO), ISSN 1312-2517. The first issue was published in 2003, ten years after BANTAO was born. Its appearance was an extremely important event in the existence of BANTAO. The first official editor of the journal was Dimitar Nenov, Varna (2003-2005), followed by Ali Basci (Izmir, Turkey) and Goce Spasovski (Skopje, Macedonia) as editor-in-chief since 2009. Over the years, the Journal has been included in the EBSCO, DOAJ and SCOPUS/SCIMAGO databases. The journal is published biannually. Until now, 345

  20. Educacion: Documento de Politica Sectorial. Tercera Edicion. (Education: Sector Policy Paper. Third Edition.)

    Science.gov (United States)

    Haddad, Wadi D.; And Others

    The present paper updates the World Bank's interpretations of education development and outlines a policy framework for lending for education. After chapters on the relationship between education and development and on the state of education development, the paper devotes a chapter to each of five issues: the expansion and equalization of…

  1. Information Warfare: Legal, Regulatory, Policy and Organizational Considerations for Assurance. Second Edition.

    Science.gov (United States)

    1996-07-04

    2-19 2-2-1 State Com puter Crim e Statutes ....................................................................... 2-44...2-2-2 Com puter Crim e Jurisdiction .......................................................................... 2-45 2-4-1 Information Warfare Policy...infrastructures from physical and cyber threats. * Propose statutory and regulatory changes. The Infrastructure Protection Task Force (IPTF): * Increase

  2. Keeping Pace with K-12 Digital Learning: An Annual Review of Policy and Practice. Eleventh Edition

    Science.gov (United States)

    Watson, John; Pape, Larry; Murin, Amy; Gemin, Butch; Vashaw, Lauren

    2014-01-01

    "Keeping Pace with K-12 Digital Learning" (2014) is the 11th in a series of annual reports that began in 2004 that examine the status of K-12 online education across the country. The report provides an overview of the latest policies, practices, and trends affecting online learning programs across all 50 states. It summarizes that at a…

  3. Wikipedia editing dynamics

    Science.gov (United States)

    Gandica, Y.; Carvalho, J.; Sampaio dos Aidos, F.

    2015-01-01

    A model for the probabilistic function followed in editing Wikipedia is presented and compared with simulations and real data. It is argued that the probability of editing is proportional to the editor's number of previous edits (preferential attachment), to the editor's fitness, and to an aging factor. Using these simple ingredients, it is possible to reproduce the results obtained for Wikipedia editing dynamics for a collection of single pages as well as the averaged results. Using a stochastic process framework, a recursive equation was obtained for the average of the number of edits per editor that seems to describe the editing behavior in Wikipedia.

  4. Process Coordination & Policy Officer | IDRC - International ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    When a policy requires updating, the applicable level of management will provide the incumbent with operational and other relevant information; the incumbent will provide Division management with information on current trends and the results of research. Together they will develop the parameters for the policy work that ...

  5. Scholarly Edition in the Digital Era: Models, Dissemination, and the Research Process

    Directory of Open Access Journals (Sweden)

    Paul Spence

    2014-01-01

    Full Text Available This article analyses scholarly edition in the digital age from both theoretical and practical perspectives, with reference to recent history in digital edition, and with special reference to research in this area in the field of digital humanities.

  6. The Role of Interstate Policy Organizations in State Higher Education Policy Processes: Perceptions of Policymakers and Policy Shapers

    Science.gov (United States)

    Michelau, Demaree K.

    2010-01-01

    Political science offers rich explanations for how different types of organizations that are focused on public policy decisions (e.g., boundary organizations, interest groups, policy networks (or communities), and think tanks) influence public policy processes (Cash, Clark, Alcock, Dickson, Eckley, Guston, Jager, and Mitchell 2003; Guston 2001;…

  7. Theories of State Analyzing the Policy Process,

    Science.gov (United States)

    1973-11-01

    Mean, early sociologists; William Graham Sumner; Kurt Lewin, the social psychologist who emphasized group cohesiveness in group dynamics; Wilfred ... Bion ; Leon Festinger, who studied "cognitive dissonance" Harold Kelley, Stanley Schachter and Dorwin Cartwright. 63 For application to policy-making in

  8. Fiscal policy lags and income adjustment processes

    International Nuclear Information System (INIS)

    De Cesare, Luigi; Sportelli, Mario

    2012-01-01

    Highlights: ► There are delays either in the government expenditure or in the tax system. ► Both delays affect fiscal policy outcomes. ► The system of differential equations with two delays may be chaotic. ► Fiscal policy outcomes might be inconsistent with their stabilization purposes. - Abstract: The interest in the impact of fiscal policy lags on economic stability increased in the last decade. Several studies have been made on delays either in the government expenditure or in the tax system, where lags exist between the accrual and the payment of taxes. Nevertheless there is in the literature no model where time delays in government expenditures and in tax revenues are considered together as it happens in the real world. In this paper we remedied this defect and proposed a macro-dynamic model where two delays appear: the first pertains to the public expenditure, the second, to the tax revenue. The resulting system of delayed differential equations is studied qualitatively and numerically. The analysis suggests that only particular combinations of the two delays make the system stable. Prevalently the system is unstable and chaotic motions may arise. This implies that the economy may need appropriate structural changes in the public sector to improve fiscal policy outcomes in such a way they may really be consistent with their stabilization purposes.

  9. Process Coordination and Policy Officer | IDRC - International ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Job Summary This job encompasses the development and maintenance of financial and administrative policies and procedures that affect all aspects of IDRC operations at head office as well as in regional offices. The job bridges functional areas and management information systems. It constitutes a key lever for the ...

  10. Developing new levels of edit

    Energy Technology Data Exchange (ETDEWEB)

    Prono, J.K.

    1997-06-01

    Since 1985, Los Alamos National Laboratory (LANL) staff have had four levels of edit to choose from for technical reports. When a CQI survey showed that both authors and editors felt the levels were not meeting author needs, LANL set about revising them. The goals were to simplify the editing process, focus editing on improving technical clarity, and ensure value added in editing. This paper describes the revision process and product--three author-based levels of edit.

  11. Policy Implementation beyond the Management of Change: A Case Study in Managing the Policy Process.

    Science.gov (United States)

    Welton, John; Evans, Jennifer

    Using the 1981 Education Act of England and Wales as a case study, this paper develops a conceptual framework of education legislation as a significant reference point in the process of negotiation and bargaining that initiates legislation and continues throughout the period of policy implementation. A model of the policy process and the…

  12. Framing and the health policy process: a scoping review.

    Science.gov (United States)

    Koon, Adam D; Hawkins, Benjamin; Mayhew, Susannah H

    2016-07-01

    Framing research seeks to understand the forces that shape human behaviour in the policy process. It assumes that policy is a social construct and can be cast in a variety of ways to imply multiple legitimate value considerations. Frames provide the cognitive means of making sense of the social world, but discordance among them forms the basis of policy contestation. Framing, as both theory and method, has proven to generate considerable insight into the nature of policy debates in a variety of disciplines. Despite its salience for understanding health policy debates; however, little is known about the ways frames influence the health policy process. A scoping review using the Arksey and O'Malley framework was conducted. The literature on framing in the health sector was reviewed using nine health and social science databases. Articles were included that explicitly reported theory and methods used, data source(s), at least one frame, frame sponsor and evidence of a given frame's effect on the health policy process. A total of 52 articles, from 1996 to 2014, and representing 12 countries, were identified. Much of the research came from the policy studies/political science literature (n = 17) and used a constructivist epistemology. The term 'frame' was used as a label to describe a variety of ideas, packaged as values, social problems, metaphors or arguments. Frames were characterized at various levels of abstraction ranging from general ideological orientations to specific policy positions. Most articles presented multiple frames and showed how actors advocated for them in a highly contested political process. Framing is increasingly an important, yet overlooked aspect of the policy process. Further analysis on frames, framing processes and frame conflict can help researchers and policymakers to understand opaque and highly charged policy issues, which may facilitate the resolution of protracted policy controversies. © The Author 2016. Published by Oxford

  13. Duelund, Marts 2012, 13th edition udg. Strasbourg/Bonn : Council of Europe/ERICarts. 78 s. (Compendium of Cultural Policies and Trends in Europe)

    DEFF Research Database (Denmark)

    Duelund, Peter

    2012-01-01

    The Council of Europe/ERICarts "Compendium of Cultural Policies and Trends in Europe, 13th edition", 2012 is a web-based and permanently updated information and monitoring system of national cultural policies in Europe. It is a long term project which aims to include all 50 member states co...... Perspective, General objectives and principles, Competence, decisionsmaking and administration, Current issues in cultural policymaking and debate,Main legal provisions in the cultural field, Financing of culture, Public institutions in the cultural infrastructure, Promoting creativity and participation......-operating within the context of the European Cultural Convention. Compendium cultural policy country profiles are mainly drawn up and updated by independent cultural policy experts (i.e. "the authors"), in consultation with respective ministries. The information presented in the updated country profiles is derived...

  14. Integration Processes of Migrants: Research Findings and Policy Challenges

    Directory of Open Access Journals (Sweden)

    Rinus Penninx

    2007-06-01

    Full Text Available This contribution discusses the integration processes of immigrants and minorities with a recent immigrant background, and the policies related to the process of settlement of these newcomers in European societies at all relevant levels: from the local level of municipalities and cities, to the national level of states, and the international level of the European Union. Within this general approach, however, a strong emphasis is put on the local level, since that is the level where such policies have to be implemented and are primarily felt, both by the immigrants themselves and by those parts of society that are most affected by immigration. To describe the current state of integration research and policies, this paper will explore in the first section the nature of integration processes, their conceptualisation and lessons from empirical studies. The reason for devoting some space to these topics is the assertion that any integration policy should be based on a thorough, scientifically-based knowledge of the processes of integration and exclusion: if a policy wants to steer such a process, it should have a clear idea of what instruments it can use possibly to intervene, in which part of the process, and at what particular moment. Such knowledge is a solid starting point for policy-making, but it is not enough. Processes of policy-making and implementation follow their own set course, which do not necessarily run parallel to the process of integration. That is why, in the following section, the author attempts to explain some of these processes. At the end of this paper he returns to the core questions of immigration and integration policies on the one hand, and the relationship between local, national and international integration policies on the other.

  15. Aging in comparative perspective: processes and policies

    National Research Council Canada - National Science Library

    Cook, Ian G; Halsall, Jamie

    2012-01-01

    .... This timely volume analyzes the aging process in various countries, with special focus on the stresses placed on their economies as the numbers of elders increase with fewer young people available...

  16. Modulation of microRNA editing, expression and processing by ADAR2 deaminase in glioblastoma.

    Science.gov (United States)

    Tomaselli, Sara; Galeano, Federica; Alon, Shahar; Raho, Susanna; Galardi, Silvia; Polito, Vinicia Assunta; Presutti, Carlo; Vincenti, Sara; Eisenberg, Eli; Locatelli, Franco; Gallo, Angela

    2015-01-13

    ADAR enzymes convert adenosines to inosines within double-stranded RNAs, including microRNA (miRNA) precursors, with important consequences on miRNA retargeting and expression. ADAR2 activity is impaired in glioblastoma and its rescue has anti-tumoral effects. However, how ADAR2 activity may impact the miRNome and the progression of glioblastoma is not known. By integrating deep-sequencing and array approaches with bioinformatics analyses and molecular studies, we show that ADAR2 is essential to edit a small number of mature miRNAs and to significantly modulate the expression of about 90 miRNAs in glioblastoma cells. Specifically, the rescue of ADAR2 activity in cancer cells recovers the edited miRNA population lost in glioblastoma cell lines and tissues, and rebalances expression of onco-miRNAs and tumor suppressor miRNAs to the levels observed in normal human brain. We report that the major effect of ADAR2 is to reduce the expression of a large number of miRNAs, most of which act as onco-miRNAs. ADAR2 can edit miR-222/221 and miR-21 precursors and decrease the expression of the corresponding mature onco-miRNAs in vivo and in vitro, with important effects on cell proliferation and migration. Our findings disclose an additional layer of complexity in miRNome regulation and provide information to better understand the impact of ADAR2 editing enzyme in glioblastoma. We propose that ADAR2 is a key factor for maintaining edited-miRNA population and balancing the expression of several essential miRNAs involved in cancer.

  17. Impact of policy game on insight and attitude to inter sectoral policy processes - EU country cases

    DEFF Research Database (Denmark)

    Lau, C.; Glümer, Charlotte; Spitters, Hilde

    Background A policy game is a structured simulated role-play dealing with highly complex decision-making in real life network settings. Its impact on health enhancing physical activity (HEPA) policy making is unexplored. We aim to explore if an internationally developed and pilot tested policy game...... a policy game at local level, with 6 months intervals, including 18–19 policy makers in each game. Data was collected using a structured questionnaire one week after implementation of the games. Participants were asked if the game had changed their insight or attitude. Results: Response rate was 83%, 89......% and 89% in NL, DK and RO respectively. Across countries the majority of participants, 60%, enhanced their nderstanding of the local HEPA policy process, the roles in the organization network, and how stakeholders can collaborate as result of the game. Most participants perceived change in insight...

  18. Science-policy processes for transboundary water governance.

    Science.gov (United States)

    Armitage, Derek; de Loë, Rob C; Morris, Michelle; Edwards, Tom W D; Gerlak, Andrea K; Hall, Roland I; Huitema, Dave; Ison, Ray; Livingstone, David; MacDonald, Glen; Mirumachi, Naho; Plummer, Ryan; Wolfe, Brent B

    2015-09-01

    In this policy perspective, we outline several conditions to support effective science-policy interaction, with a particular emphasis on improving water governance in transboundary basins. Key conditions include (1) recognizing that science is a crucial but bounded input into water resource decision-making processes; (2) establishing conditions for collaboration and shared commitment among actors; (3) understanding that social or group-learning processes linked to science-policy interaction are enhanced through greater collaboration; (4) accepting that the collaborative production of knowledge about hydrological issues and associated socioeconomic change and institutional responses is essential to build legitimate decision-making processes; and (5) engaging boundary organizations and informal networks of scientists, policy makers, and civil society. We elaborate on these conditions with a diverse set of international examples drawn from a synthesis of our collective experiences in assessing the opportunities and constraints (including the role of power relations) related to governance for water in transboundary settings.

  19. Public participation in the process of local public health policy, using policy network analysis.

    Science.gov (United States)

    Park, Yukyung; Kim, Chang-Yup; You, Myoung Soon; Lee, Kun Sei; Park, Eunyoung

    2014-11-01

    To assess the current public participation in-local health policy and its implications through the analysis of policy networks in health center programs. We examined the decision-making process in sub-health center installations and the implementation process in metabolic syndrome management program cases in two districts ('gu's) of Seoul. Participants of the policy network were selected by the snowballing method and completed self-administered questionnaires. Actors, the interactions among actors, and the characteristics of the network were analyzed by Netminer. The results showed that the public is not yet actively participating in the local public health policy processes of decision-making and implementation. In the decision-making process, most of the network actors were in the public sector, while the private sector was a minor actor and participated in only a limited number of issues after the major decisions were made. In the implementation process, the program was led by the health center, while other actors participated passively. Public participation in Korean public health policy is not yet well activated. Preliminary discussions with various stakeholders, including civil society, are needed before making important local public health policy decisions. In addition, efforts to include local institutions and residents in the implementation process with the public officials are necessary to improve the situation.

  20. Towards social acceptance of plant breeding by genome editing

    OpenAIRE

    Araki, Motoko; Ishii, Tetsuya

    2015-01-01

    Although genome-editing technologies facilitate efficient plant breeding without introducing a transgene, it is creating indistinct boundaries in the regulation of genetically modified organisms (GMOs). Rapid advances in plant breeding by genome-editing require the establishment of a new global policy for the new biotechnology, while filling the gap between process-based and product-based GMO regulations. In this Opinion article we review recent developments in producing major crops using gen...

  1. Alcohol policy in South Africa: a review of policy development processes between 1994 and 2009.

    Science.gov (United States)

    Parry, Charles D H

    2010-08-01

    Implementation of effective policies to reduce harmful alcohol consumption requires both a good understanding of the policy development process and which strategies are likely to work. To contribute to this understanding by reviewing four specific policy development initiatives that have taken place in South Africa between 1994 and 2009: restrictions on alcohol advertising and counter-advertising, regulation of retail sales of alcohol, alcohol taxation and controls on alcohol packaging. Material was drawn from a record of meetings and conferences held between 1994 and 2009 and a database of reports, newspaper clippings and policy documentation. When the policy process resulted in a concrete outcome there was always a clear recognition of the problem and policy alternatives, but success was more likely if there was an alignment of 'political' forces and/or when there was a determined bureaucracy. The impact of the other factors such as the media, community mobilization, non-governmental organizations (NGOs), the liquor industry and research are also discussed. Future avenues for policy research are identified, including the need for more systematic studies that give greater consideration to economic factors. Alcohol policy development in South Africa takes place in a piecemeal fashion and is the product of various competing influences. Having a comprehensive national alcohol strategy cutting across different sectors may be a better way for other developing countries to proceed.

  2. Triple-frequency TurboEdit Cycle-slip Processing Method of Weakening Ionospheric Activity

    Directory of Open Access Journals (Sweden)

    HUANG Lingyong

    2015-08-01

    Full Text Available The existing triple-frequency cycle-slip detection method usually can not detect and repair the cycle-slip correctly in the ionospheric activity phase or when the magnetic storm happening. To solve the problem, the triple-frequency TurboEdit method for weakening the ionospheric error is advanced based on the dual-frequency TurboEdit method. Both the triple-frequency geometry-free and ionospheric-free combination and second-order time-difference phase geometry-free combination in this algorithm can whittle the influence of ionospheric error effectively. And then, the triple-frequency data is used to validate this algorithm, the experiment results show that this method can weaken the ionospheric error and realize the no-difference dynamicreal-time cycle-slip detection and correction under ionospheric activity phase.

  3. Why UFI nudges will get stuck in the policy process.

    Science.gov (United States)

    Lawson, Joshua; Howard, Brendan

    2012-01-01

    User financial incentives (UFI), in the context of behavioural public policy, have the potential to shape Canadian health policy by replacing or augmenting traditional information-based mechanisms and by imparting a viewpoint that has traditionally been foreign to the public sphere. Whether or not UFI and more traditional "nudges" should be used, they will likely be limited by traditional moral, efficacy and cost/ benefit challenges, as well as the political and bureaucratic impediments that emerge throughout the policy implementation process. These challenges will likely preclude UFI and nudges from having a transformative effect on public policy, but this new school of thought will likely gain prominence through more amorphous means as more individuals learn and adopt its central theory. We should be excited about the potential of UFI and the use of behavioural public policy, but should temper our excitement with realistic expectations about how extensively such an approach should and will be used.

  4. Dual core processing: MRB1 is an emerging kinetoplast RNA editing complex

    Czech Academy of Sciences Publication Activity Database

    Hashimi, Hassan; Zimmer, S.L.; Ammerman, M. L.; Read, L. K.; Lukeš, Julius

    2013-01-01

    Roč. 29, č. 2 (2013), s. 91-99 ISSN 1471-4922 R&D Projects: GA ČR GAP305/12/2261; GA ČR GA204/09/1667 Institutional support: RVO:60077344 Keywords : kinetoplastida * trypanosome * RNA editing * protein complexes * RECC * MRB1 Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 6.217, year: 2013 http://www.sciencedirect.com/science/article/pii/S1471492212001985

  5. State health agencies and the legislative policy process.

    Science.gov (United States)

    Williams-Crowe, S M; Aultman, T V

    1994-01-01

    A new era of health care reform places increasing pressure on public health leaders and agencies to participate in the public policy arena. Public health professionals have long been comfortable in providing the scientific knowledge base required in policy development. What has been more recent in its evolution, however, is recognition that they must also play an active role in leading and shaping the debate over policy. A profile of effective State legislative policy "entrepreneurs" and their strategies has been developed to assist health agencies in developing such a leadership position. Based on the experiences of State legislative liaison officers, specific strategies for dealing with State legislatures have been identified and are organized into five key areas--agency organization, staff skills, communications, negotiation, and active ongoing involvement. A public health agency must be organized effectively to participate in the legislative policy process. Typically, effective agencies centralize responsibility for policy activities and promote broad and coordinated participation throughout the organization. Playing a key role in the agency's political interventions, the legislative liaison office should be staffed with persons possessing excellent interpersonal skills and a high degree of technical competence. Of central importance to effective legislative policy entrepreneurship is the ability to communicate the agency's position clearly. This includes setting forward a focused policy agenda, documenting policy issues in a meaningful manner, and reaching legislators with the proper information. Once a matter is on the legislative agenda, the agency must be prepared to negotiate and build broad support for the measure. Finally, public health agencies must be active policy players. To take advantage of new opportunities for action, the public health (policy) leader must monitor the political environment continually.By working to anticipate and formulate

  6. Finnish Higher Education Policy and the Ongoing Bologna Process.

    Science.gov (United States)

    Ahola, Sakari; Mesikammen, Jani

    2003-01-01

    Describes the Bologna Process (a European-wide project to create a European Higher Education Area and harmonize degree structures), examining how educational policy has reached a stage for considering a European Higher Education Area that examines concepts of harmonization and the Bologna Process. Discusses future scenarios, highlighting why…

  7. Policy processes underpinning universal health insurance in Vietnam

    Directory of Open Access Journals (Sweden)

    Bui T. T. Ha

    2014-09-01

    Full Text Available Background: In almost 30 years since economic reforms or ‘renovation’ (Doimoi were launched, Vietnam has achieved remarkably good health results, in many cases matching those in much higher income countries. This study explores the contribution made by Universal Health Insurance (UHI policies, focusing on the past 15 years. We conducted a mixed method study to describe and assess the policy process relating to health insurance, from agenda setting through implementation and evaluation. Design: The qualitative research methods implemented in this study were 30 in-depth interviews, 4 focus group discussions, expert consultancy, and 420 secondary data review. The data were analyzed by NVivo 7.0. Results: Health insurance in Vietnam was introduced in 1992 and has been elaborated over a 20-year time frame. These processes relate to moving from a contingent to a gradually expanded target population, expanding the scope of the benefit package, and reducing the financial contribution from the insured. The target groups expanded to include 66.8% of the population by 2012. We characterized the policy process relating to UHI as incremental with a learning-by-doing approach, with an emphasis on increasing coverage rather than ensuring a basic service package and financial protection. There was limited involvement of civil society organizations and users in all policy processes. Intertwined political economy factors influenced the policy processes. Conclusions: Incremental policy processes, characterized by a learning-by-doing approach, is appropriate for countries attempting to introduce new health institutions, such as health insurance in Vietnam. Vietnam should continue to mobilize resources in sustainable and viable ways to support the target groups. The country should also adopt a multi-pronged approach to achieving universal access to health services, beyond health insurance.

  8. Policy processes underpinning universal health insurance in Vietnam.

    Science.gov (United States)

    Ha, Bui T T; Frizen, Scott; Thi, Le M; Duong, Doan T T; Duc, Duong M

    2014-01-01

    In almost 30 years since economic reforms or 'renovation' (Doimoi) were launched, Vietnam has achieved remarkably good health results, in many cases matching those in much higher income countries. This study explores the contribution made by Universal Health Insurance (UHI) policies, focusing on the past 15 years. We conducted a mixed method study to describe and assess the policy process relating to health insurance, from agenda setting through implementation and evaluation. The qualitative research methods implemented in this study were 30 in-depth interviews, 4 focus group discussions, expert consultancy, and 420 secondary data review. The data were analyzed by NVivo 7.0. Health insurance in Vietnam was introduced in 1992 and has been elaborated over a 20-year time frame. These processes relate to moving from a contingent to a gradually expanded target population, expanding the scope of the benefit package, and reducing the financial contribution from the insured. The target groups expanded to include 66.8% of the population by 2012. We characterized the policy process relating to UHI as incremental with a learning-by-doing approach, with an emphasis on increasing coverage rather than ensuring a basic service package and financial protection. There was limited involvement of civil society organizations and users in all policy processes. Intertwined political economy factors influenced the policy processes. Incremental policy processes, characterized by a learning-by-doing approach, is appropriate for countries attempting to introduce new health institutions, such as health insurance in Vietnam. Vietnam should continue to mobilize resources in sustainable and viable ways to support the target groups. The country should also adopt a multi-pronged approach to achieving universal access to health services, beyond health insurance.

  9. 'Race', disadvantage, and policy processes in British planning

    OpenAIRE

    H Thomas; V Krishnarayan

    1994-01-01

    In this paper some of the mechanisms by which black and ethnic minorities can be put at a particular disadvantage within the planning system in Britain (and how these processes can be challenged) are examined. A number of types of policy processes operating in British planning are identified, and, drawing on a range of secondary and primary data, the influence of black and ethnic minorities within these processes are analysed. The paper is concluded with a review of the possibilities for the ...

  10. Processing Dante’s Commedia: From Sanguineti’s Edition to Digital Tools [Review of: Dante Alighieri Commedia A Digital Edition, Prue Shaw (ed.), 2010.

    NARCIS (Netherlands)

    Spadini, E.

    2015-01-01

    The Commedia project aims to investigate the manuscript transmission of the poem, using Sanguineti’s previous edition and checking the validity of his stemma with computer methods. Full transcriptions of the seven selected witnesses are provided alongside the corresponding facsimiles. The end

  11. Stakeholders Analysis of Policy-Making Process: The Case of Timber Legality Policy on Private Forest

    Directory of Open Access Journals (Sweden)

    Mulyaningrum Mulyaningrum

    2013-08-01

    Full Text Available The objective of the study is to identify and measure the relationships among stakeholders that influence the process of policy-making in defining legality of timber from private forests. The study focuses on the policy-making process of the Ministry of Forestry Regulation P.38/Menhut-II/2009 on Standard and Guidelines for Assessment of Sustainable Forest Management Performance and Timber Legality Verification of Concessionaire or of the Private Forest License Holder as the subject that has been implemented in several private forest management units as follow: Giri Mukti Wana Tirta in Lampung, Koperasi Serba Usaha APIK in Bali, Koperasi Hutan Jaya Lestari in South East Sulawesi, and Koperasi Wana Lestari Menoreh Kulonprogo in Yogyakarta. This research used a qualitative approach and the analysis method used in this research is a modified-stakeholder analysis that developed by ODA (1995, Reitbergen et al. (1998, and Mayer (2005. The stakeholder analysis shows that the interests and influences do not consider private forest farmers as primary stakeholder during  the process of policy formulation.  The strong national and international interests, supported by high authority could not be influnced by the role of the NGOs and academicians. The imbalance of responsibilities, rights, and revenues that was experienced by  farmers as the manager of private forest when started implementing the policy was more as burdens, it means implementation of the policy was more as burdens. Strong relationships between the Ministry of Forestry with the state as a core could not empower the relationship with private forest farmers. As result, policy assumptions cannot be implemented properly.Keywords: policy making process, timber legality, private forest, stakeholder.DOI: 10.7226/jtfm.19.2.156

  12. Healthy kids: Making school health policy a participatory learning process

    DEFF Research Database (Denmark)

    Stjernqvist, Nanna Wurr; Bruselius-Jensen, Maria; Høstgaard Bonde, Ane

    programmes. Simultaneously a staff health team is formed from existing organisational structures, integrating local knowledge and building support for school policy making based on the pupils’ visions. A pilot study - applying the model in one Danish elementary school - has been conducted as an action...... was weakhindering sustainable health changes. Conclusion Findings indicate that integrating school policy processes into the teaching of curriculum might pave the way for schools to engage in health promotion. But further knowledge on how to likewise engage the staff on an organisational level is needed....

  13. Interactive policy processes: a challenge for street-level bureaucrats

    DEFF Research Database (Denmark)

    Agger, Annika; Damgaard, Bodil

    2018-01-01

    Street-level bureaucrats (SLB) are, according to the literature, assigned a crucial role providing better policy implementation and generating trust between the system and the citizens. In this article, we argue that Lipsky’s division between public managers and SLB needs an update. Today more...... converting public managers to SLB. The key question raised is thus: What kind of skills and capabilities of SLB are needed in more interactive forms of public policy making? And what are the consequences for how the universities educate these groups?’ Drawing on a study of 32 urban professionals that work...... public managers are expected to work closely and directly with affected stakeholders in order to solve cross-cutting ‘wicked problems’. More interactive and participative collaborative policy processes increasingly require public managers to move from back-office work to front-office work, in effect...

  14. The Hinkley Point decision: An analysis of the policy process

    International Nuclear Information System (INIS)

    Thomas, Stephen

    2016-01-01

    In 2006, the British government launched a policy to build nuclear power reactors based on a claim that the power produced would be competitive with fossil fuel and would require no public subsidy. A decade later, it is not clear how many, if any, orders will be placed and the claims on costs and subsidies have proved false. Despite this failure to deliver, the policy is still being pursued with undiminished determination. The finance model that is now proposed is seen as a model other European countries can follow so the success or otherwise of the British nuclear programme will have implications outside the UK. This paper contends that the checks and balances that should weed out misguided policies, have failed. It argues that the most serious failure is with the civil service and its inability to provide politicians with high quality advice – truth to power. It concludes that the failure is likely to be due to the unwillingness of politicians to listen to opinions that conflict with their beliefs. Other weaknesses include the lack of energy expertise in the media, the unwillingness of the public to engage in the policy process and the impotence of Parliamentary Committees. - Highlights: •Britain's nuclear power policy is failing due to high costs and problems of finance. •This has implications for European countries who want to use the same financing model. •The continued pursuit of a failing policy is due to poor advice from civil servants. •Lack of expertise in the media and lack of public engagement have contributed. •Parliamentary processes have not provided proper critical scrutiny.

  15. Identification of Optimal Policies in Markov Decision Processes

    Czech Academy of Sciences Publication Activity Database

    Sladký, Karel

    46 2010, č. 3 (2010), s. 558-570 ISSN 0023-5954. [ International Conference on Mathematical Methods in Economy and Industry. České Budějovice, 15.06.2009-18.06.2009] R&D Projects: GA ČR(CZ) GA402/08/0107; GA ČR GA402/07/1113 Institutional research plan: CEZ:AV0Z10750506 Keywords : finite state Markov decision processes * discounted and average costs * elimination of suboptimal policies Subject RIV: BB - Applied Statistics, Operational Research Impact factor: 0.461, year: 2010 http://library.utia.cas.cz/separaty/2010/E/sladky-identification of optimal policies in markov decision processes.pdf

  16. A Handbook of Globalisation and Environmental Policy, 2nd edition. National Governments Interventions in a Global Arena

    NARCIS (Netherlands)

    Wijen, F.H.; Zoeteman, B.C.J.; Pieters, J.; van Seters, P.C.M.

    2012-01-01

    In the current era of globalisation, national governments are increasingly exposed to international influences that present new constraints and opportunities for domestic environmental policies. This comprehensive, revised Handbook pushes the frontiers of theoretical and empirical knowledge, and

  17. Defending the scientific integrity of conservation-policy processes.

    Science.gov (United States)

    Carroll, Carlos; Hartl, Brett; Goldman, Gretchen T; Rohlf, Daniel J; Treves, Adrian; Kerr, Jeremy T; Ritchie, Euan G; Kingsford, Richard T; Gibbs, Katherine E; Maron, Martine; Watson, James E M

    2017-10-01

    Government agencies faced with politically controversial decisions often discount or ignore scientific information, whether from agency staff or nongovernmental scientists. Recent developments in scientific integrity (the ability to perform, use, communicate, and publish science free from censorship or political interference) in Canada, Australia, and the United States demonstrate a similar trajectory. A perceived increase in scientific-integrity abuses provokes concerted pressure by the scientific community, leading to efforts to improve scientific-integrity protections under a new administration. However, protections are often inconsistently applied and are at risk of reversal under administrations publicly hostile to evidence-based policy. We compared recent challenges to scientific integrity to determine what aspects of scientific input into conservation policy are most at risk of political distortion and what can be done to strengthen safeguards against such abuses. To ensure the integrity of outbound communications from government scientists to the public, we suggest governments strengthen scientific integrity policies, include scientists' right to speak freely in collective-bargaining agreements, guarantee public access to scientific information, and strengthen agency culture supporting scientific integrity. To ensure the transparency and integrity with which information from nongovernmental scientists (e.g., submitted comments or formal policy reviews) informs the policy process, we suggest governments broaden the scope of independent reviews, ensure greater diversity of expert input and transparency regarding conflicts of interest, require a substantive response to input from agencies, and engage proactively with scientific societies. For their part, scientists and scientific societies have a responsibility to engage with the public to affirm that science is a crucial resource for developing evidence-based policy and regulations in the public interest.

  18. U.S. Army War College Guide to National Security Issues. Third Edition, Volume 2. National Security Policy and Strategy

    Science.gov (United States)

    2008-06-01

    to Buddhist monks and nuns.7 Similarly, a sacred Jain text says, “One may not kill, ill-use, insult, torment, or persecute any kind of living being...While this power struggle illustrates direct conflict, how does the Congress routinely influence policy and strategy formulation in the national...logically flows from its appropriations role.7 The leaders of the foreign policy agencies routinely go to Capitol Hill to testify before various committees

  19. Successful Family Language Policy: Parents, Children and Educators in Interaction, edited by Mila Schwartz and Anna Verschik. Multilingual Matters, 2013.

    OpenAIRE

    Walls, Francesca

    2015-01-01

    Demonstrating a burgeoning interest in the field of family language policy (FLP) around the world, Successful Family Language Policy comprises several contributions from researchers working on multiple different contexts, united in their aim to address the key question of what makes some families successful in achieving bi- or multilingual outcomes for their children and others not.  Many factors that might contribute towards or jeopardise success are put forward throughout the course of...

  20. PROCESS APPROACH TO CULTURAL POLICY IN THE REGIONAL ASPECT

    Directory of Open Access Journals (Sweden)

    Maryna Lavryshsheva

    2017-02-01

    Characteristics of cultural policy, as a process, i.e. procedural approach, allows us to see the specific aspects of interaction of subjects over the governmental authorities. However, due to the fact, that in its scale cultural process is the same as political environment of the state, some scientists identify it either with politics in general or with the totality of the shares of behavioral government entities, change their status and influence. Supporters of the institutional approach associates the cultural political process with the functioning and the transformation of the government institutionы, based on a set of the political system reactions on the environmental challenges. As we speak in the current economic conditions in Ukraine is actual the development of anti-crisis measures for the rehabilitation and development of the conceptual approach of cultural policies in the region. As such, the obvious is the development of a measures set by all courses of the plan, that will mutualize the key goals, objectives and tools into a uniform system of measures. This plan should provide the combined model in the region and provide a transition to the zonal management principle of the transition period. In the plan it is also should be provided institutional support for the proposed measures, namely the mechanisms of technological and socio-cultural issues implementation in range of the cultural policy of the society [1, p.18].

  1. Photo Editing: A Neglected Art.

    Science.gov (United States)

    Bergeman, Rich

    1987-01-01

    Offers guidelines for using photographs effectively in campus newspapers. Reviews the stages in the photo editing process, suggests alternatives to traditional photographic approaches, and offers technical advice. (AYC)

  2. Towards social acceptance of plant breeding by genome editing.

    Science.gov (United States)

    Araki, Motoko; Ishii, Tetsuya

    2015-03-01

    Although genome-editing technologies facilitate efficient plant breeding without introducing a transgene, it is creating indistinct boundaries in the regulation of genetically modified organisms (GMOs). Rapid advances in plant breeding by genome-editing require the establishment of a new global policy for the new biotechnology, while filling the gap between process-based and product-based GMO regulations. In this Opinion article we review recent developments in producing major crops using genome-editing, and we propose a regulatory model that takes into account the various methodologies to achieve genetic modifications as well as the resulting types of mutation. Moreover, we discuss the future integration of genome-editing crops into society, specifically a possible response to the 'Right to Know' movement which demands labeling of food that contains genetically engineered ingredients. Copyright © 2015 Elsevier Ltd. All rights reserved.

  3. National Environmental Policy Act guidance: A model process

    International Nuclear Information System (INIS)

    Angle, B.M.; Lockhart, V.A.T.; Sema, B.; Tuott, L.C.; Irving, J.S.

    1995-04-01

    The ''Model National Environmental Policy Act (NEPA) Process'' includes: References to regulations, guidance documents, and plans; training programs; procedures; and computer databases. Legislative Acts and reference documents from Congress, US Department of Energy, and Lockheed Idaho Technologies Company provide the bases for conducting NEPA at the Idaho National Engineering Laboratory (INEL). Lockheed Idaho Technologies Company (LITCO) NEPA / Permitting Department, the Contractor Environmental Organization (CEO) is responsible for developing and maintaining LITCO NEPA and permitting policies, guidance, and procedures. The CEO develops procedures to conduct environmental evaluations based on NEPA, Council on Environmental Quality (CEQ) regulations, and DOE guidance. This procedure includes preparation or support of environmental checklists, categorical exclusion determinations, environmental assessment determinations, environmental assessments, and environmental impact statements. In addition, the CEO uses this information to train personnel conducting environmental evaluations at the INEL. Streamlining these procedures fosters efficient use of resources, quality documents, and better decisions on proposed actions

  4. genome editing

    Indian Academy of Sciences (India)

    2016-02-11

    Feb 11, 2016 ... terms in molecular biology, but I have the premonition that we are living a similar event, with identically dra- ... meaning of 'editing' occurred in the French language and in biology. In both cases, computers played ..... Tiegs SL, Russell DM and Nemazee D 1993 Receptor editing in self-reactive bone marrow.

  5. Science, Society, and America's Nuclear Waste: The Nuclear Waste Policy Act, Unit 3. Teacher Guide. Second Edition.

    Science.gov (United States)

    Department of Energy, Washington, DC. Office of Civilian Radioactive Waste Management, Washington, DC.

    This guide is Unit 3 of the four-part series, Science, Society, and America's Nuclear Waste, produced by the U.S. Department of Energy's Office of Civilian Radioactive Waste Management. The goal of this unit is to identify the key elements of the United States' nuclear waste dilemma and introduce the Nuclear Waste Policy Act and the role of the…

  6. The Process Architecture of EU Territorial Cohesion Policy

    Directory of Open Access Journals (Sweden)

    Andreas Faludi

    2010-08-01

    Full Text Available When preparing the European Spatial Development Perspective (ESDP, Member States were supported by the European Commission but denied the EU a competence in the matter. Currently, the Treaty of Lisbon identifies territorial cohesion as a competence shared between the Union and the Member States. This paper is about the process architecture of territorial cohesion policy. In the past, this architecture resembled the Open Method of Coordination (OMC which the White Paper on European Governance praised, but only in areas where there was no EU competence. This reflected zero-sum thinking which may continue even under the Lisbon Treaty. After all, for as long as territorial cohesion was not a competence, voluntary cooperation as practiced in the ESDP process was pursued in this way. However, the practice of EU policies, even in areas where there is an EU competence, often exhibits features of the OMC. Surprisingly effective innovations hold the promise of rendering institutions of decision making comprehensible and democratically accountable. In the EU as a functioning polity decision making is thus at least part deliberative so that actors’ preferences are transformed by the force of the better argument. This brings into focus the socialisation of the deliberators into epistemic communities. Largely an informal process, this is reminiscent of European spatial planning having been characterised as a learning process.

  7. Development of oral health policy in Nigeria: an analysis of the role of context, actors and policy process.

    Science.gov (United States)

    Etiaba, Enyi; Uguru, Nkoli; Ebenso, Bassey; Russo, Giuliano; Ezumah, Nkoli; Uzochukwu, Benjamin; Onwujekwe, Obinna

    2015-05-06

    In Nigeria, there is a high burden of oral health diseases, poor coordination of health services and human resources for delivery of oral health services. Previous attempts to develop an Oral Health Policy (OHP) to decrease the oral disease burden failed. However, a policy was eventually developed in November 2012. This paper explores the role of contextual factors, actors and the policy process in the development of the OHP and possible reasons why the current approved OHP succeeded. The study was undertaken across Nigeria; information gathered through document reviews and in-depth interviews with five groups of purposively selected respondents. Analysis of the policy development process was guided by the policy triangle framework, examining context, policy process and actors involved in the policy development. The foremost enabling factor was the yearning among policy actors for a policy, having had four failed attempts. Other factors were the presence of a democratically elected government, a framework for health sector reform instituted by the Federal Ministry of Health (FMOH). The approved OHP went through all stages required for policy development unlike the previous attempts. Three groups of actors played crucial roles in the process, namely academics/researchers, development partners and policy makers. They either had decision making powers or influenced policy through funding or technical ability to generate credible research evidence, all sharing a common interest in developing the OHP. Although evidence was used to inform the development of the policy, the complex interactions between the context and actors facilitated its approval. The OHP development succeeded through a complex inter-relationship of context, process and actors, clearly illustrating that none of these factors could have, in isolation, catalyzed the policy development. Availability of evidence is necessary but not sufficient for developing policies in this area. Wider socio

  8. The Faroe Islands’ Security Policy in a Process of Devolution

    Directory of Open Access Journals (Sweden)

    Beinta í Jákobsstovu

    2012-12-01

    Full Text Available Since the late 1990s there has been a remarkable change in the institutional context of safety and security policies for the Faroes. The end of the Cold War led to a reduction in the strategic importance of, and military presence in, the islands. However, today Faroese sea and air space is increasingly exposed to heavy civilian traffic due to expected oil production as well as new sailing routes from the High North. The Faroese government is in a process, nearly completed, of taking over the full responsibility for societal security policy, a field it used to share with the Danish state authorities. In April 2002, the Faroese authorities took over the responsibility for SAR in Faroese sea territory and established a MRCC Center in Tórshavn. A new civic security law was passed by Løgtingið (the parliament in May 2012. This article discusses micro-states’ options in the international arena; provides a brief overview of the history of Faroese security policy; and discusses the present and future challenges involved in assuring protection and rescue services for the Faroese region of the North Atlantic.

  9. Improvements in anatomy knowledge when utilizing a novel cyclical "Observe-Reflect-Draw-Edit-Repeat" learning process.

    Science.gov (United States)

    Backhouse, Mark; Fitzpatrick, Michael; Hutchinson, Joseph; Thandi, Charankumal S; Keenan, Iain D

    2017-01-01

    Innovative educational strategies can provide variety and enhance student learning while addressing complex logistical and financial issues facing modern anatomy education. Observe-Reflect-Draw-Edit-Repeat (ORDER), a novel cyclical artistic process, has been designed based on cognitivist and constructivist learning theories, and on processes of critical observation, reflection and drawing in anatomy learning. ORDER was initially investigated in the context of a compulsory first year surface anatomy practical (ORDER-SAP) at a United Kingdom medical school in which a cross-over trial with pre-post anatomy knowledge testing was utilized and student perceptions were identified. Despite positive perceptions of ORDER-SAP, medical student (n = 154) pre-post knowledge test scores were significantly greater (P artistic preferences when using ORDER were not significantly different (P > 0.05) to those students without these characteristics. These findings will be of value to anatomy instructors seeking to engage students from diverse learning backgrounds in a research-led, innovative, time and cost-effective learning method, in the context of contrasting learning environments. Anat Sci Educ 10: 7-22. © 2016 American Association of Anatomists. © 2016 American Association of Anatomists.

  10. Adaptive and compliant policy implementation : Creating administrative processes using semantic web services and business rules

    NARCIS (Netherlands)

    Gong, Y.; Janssen, M.

    2013-01-01

    Adapting to and complying with frequently changing policy against low costs requires flexible business processes. Yet, existing systems are unrelated, consist of operating silos, involve many human translation tasks and policies are hardcoded in business processes. From a technology perspective,

  11. Solar Energy: Materials, Materials Handling, and Fabrication Processes: Student Material. First Edition.

    Science.gov (United States)

    Bolin, William Everet; Orsak, Charles G., Jr.

    Designed for student use in "Materials, Materials Handling, and Fabrication Processes," one of 11 courses in a 2-year associate degree program in solar technology, this manual provides readings, exercises, worksheets, bibliographies, and illustrations for 13 course modules. The manual, which corresponds to an instructor guide for the…

  12. A comprehensive glossary of autophagy-related molecules and processes (2nd edition)

    DEFF Research Database (Denmark)

    Klionsky, Daniel J; Baehrecke, Eric H; Brumell, John H

    2011-01-01

    The study of autophagy is rapidly expanding, and our knowledge of the molecular mechanism and its connections to a wide range of physiological processes has increased substantially in the past decade. The vocabulary associated with autophagy has grown concomitantly. In fact, it is difficult for r...

  13. Discovering the knowledge creation process of an expert group in women-friendly policy: The policy case of Seoul City.

    Science.gov (United States)

    Oh, Young Sam; Nam, SungHee; Kim, Yuna

    2016-01-01

    This research explores how expert knowledge is created in the process of women-friendly policy making, based on actor network theory (ANT). To address this purpose, this study uses the "Women's Happiness in the City of Seoul" policy initiated by the local government of Seoul as one example of policy development. Research findings demonstrate that knowledge creation in expert groups followed the four stages suggested by ANT. In addition, this study found that various types of knowledge emerged from individual experts. This research elucidates the process of knowledge creation and its meanings for women-friendly policy.

  14. Processes of convergence and divergence in the policy formulation of policing strategies for European metropolises

    NARCIS (Netherlands)

    Devroe, E.; Edwards, A.M.; Ponsaers, P.

    2017-01-01

    This edited collection forms part of a broader, ongoing, research project, ‘The Policing European Metropolises Project’ (‘PEMP’). The Project has its origins in a network of researchers interested in the significance of sub-national policing for understanding processes of convergence and divergence

  15. From 2020 to 2030, from Copenhagen to Paris: a mindset change for the European climate policy? (French Edition)

    International Nuclear Information System (INIS)

    Mathieu, Carole

    2014-01-01

    The European Councils of March 2007 and October 2014 have defined the major guidelines of the European climate policy for the 2010-2020 and 2020-2030 decades. These commitments have then been used as negotiation road-maps for two major conferences on climate held under the United-Nations umbrella, in Copenhagen in 2009 and in Paris in December 2015. In both cases, the aim was, and still is, to reach a global agreement to take over the Kyoto Protocol. The first one was a failure for the European diplomacy and all hopes are now placed in the second, which may well be the last chance for the international climate talks. After seven years, time frames look similar but the context is very different. Domestically, the economic crisis has constrained the investment capacity of Member States and pushed competitiveness higher in the ranks of priorities. Internationally, the centre of gravity of energy demand and greenhouse gases emissions has shifted to emerging countries, advocating for an update of the North-South paradigm which had governed the Kyoto protocol. Lastly, although there is no coordinated action against global warming at this stage, the urgent need to act receives a wider support and more and more initiatives are taken, such as the ones recently announced by China and the United-States. Because of these elements, among others, the EU cannot simply extend the approach initiated seven years ago. The European climate policy opens a new chapter and the conclusions of the European Council of October 2014 have clearly set the tone. A change of mind-set may have occurred, in the sense that the 2030 targets reaffirm Europe's commitment to the shift towards a low carbon economy, while instigating more flexibility to ensure stronger cost-effectiveness. It is a strong signal for the world but this renewed approach still needs to be consolidated, both in the way of implementing the key reforms announced and in the way of approaching the Paris conference

  16. Political Limits to the Processing of Policy Problems

    Directory of Open Access Journals (Sweden)

    Peter J. May

    2013-07-01

    Full Text Available This contribution addresses political limits to the processing of policy problems in the United States. Our foci are the forces that limit policymakers' attention to different aspects of problems and how this affects the prospects for problem resolution. We theorize about three sets of forces: interest engagement, linkages among relevant institutions for policymaking, and partisan conflict. We show how the interplay of these forces limits efforts to address complex problems. Based on secondary accounts, we consider these underlying dynamics for ten complex problems. These include the thorny problems of the financial crisis, climate change, and health care; the persistent problems of K-12 education, drug abuse, and food safety; and the looming problems associated with critical infrastructure, the obesity epidemic, ocean health, and terrorism and extreme events. From these accounts we identify different patterns that we label fractured, allied, bureaucratic, and anemic policymaking.

  17. How do external donors influence national health policy processes? Experiences of domestic policy actors in Cambodia and Pakistan.

    Science.gov (United States)

    Khan, Mishal S; Meghani, Ankita; Liverani, Marco; Roychowdhury, Imara; Parkhurst, Justin

    2018-03-01

    Although concerns have historically been raised about the influence of external donors on health policy process in recipient countries, remarkably few studies have investigated perspectives and experiences of domestic policymakers and advisers. This study examines donor influence at different stages of the health policy process (priority setting, policy formulation, policy implementation and monitoring and evaluation) in two aid-dependent LMICs, Cambodia and Pakistan. It identifies mechanisms through which asymmetries in influence between donors and domestic policy actors emerge. We conducted 24 key informant interviews-14 in Pakistan and 10 in Cambodia-with high-level decision-makers who inform or authorize health priority setting, allocate resources and/or are responsible for policy implementation, identifying three routes of influence: financial resources, technical expertise and indirect financial and political incentives. We used both inductive and deductive approaches to analyse the data. Our findings indicate that different routes of influence emerged depending on the stage of the policy process. Control of financial resources was the most commonly identified route by which donors influenced priority setting and policy implementation. Greater (perceived) technical expertise played an important role in donor influence at the policy formulation stage. Donors' power in influencing decisions, particularly during the final (monitoring and evaluation) stage of the policy process, was mediated by their ability to control indirect financial and political incentives as well as direct control of financial resources. This study thus helps unpack the nuances of donor influence over health policymaking in these settings, and can potentially indicate areas that require attention to increase the ownership of domestic actors of their countries' health policy processes. © The Author(s) 2017. Published by Oxford University Press in association with The London School of

  18. U.S. Trade and Investment Policy Making Process

    Science.gov (United States)

    Overall, EPA’s trade and environment policy organization is designed to create a flexible and collaborative mechanism so that EPA can participate fully and effectively in the development and implementation of U.S. trade and environment policy.

  19. Environmental Education Policy Processes in the Southern African ...

    African Journals Online (AJOL)

    … in ..... documentation, in keeping with the broad understanding of policy outlined at the beginning of this paper, the audit showed .... School environmental policy development is an emerging trend in the southern African region. Initiatives like ...

  20. Towards improved policy processes for promoting innovation in renewable electricity technologies in the UK

    International Nuclear Information System (INIS)

    Foxon, T.J.; Pearson, P.J.G.

    2007-01-01

    This paper analyses recent, current and potential future relations between policy processes and substantive outcomes in UK low carbon innovation policy, focussing on policies relating to renewable electricity generation technologies. It examines the development of policy processes relating to the adoption and implementation of the Renewables Obligation and how these may affect the current and likely future success of the Obligation in promoting low carbon innovation. It examines the new policy and institutional processes put in place in the 2003 Energy White Paper and argues that these are unlikely to provide the strategic long-term framework needed to realise the ambitious goals for UK energy policy set out in the White Paper. Finally, it outlines some suggestions for further development of policy processes to facilitate improved delivery of these goals, based on guiding principles for sustainable innovation policy processes, developed by the authors and their colleagues

  1. Studying and evaluating pharmaceutical policy--becoming a part of the policy and consultative process

    DEFF Research Database (Denmark)

    Almarsdóttir, Anna Birna; Traulsen, Janine M

    2006-01-01

    In this last article in the series the authors focus on the issue of researching and evaluating pharmaceutical policy. The past five articles made an argument for why pharmaceutical policy is important and why it is different from health policy. The evidence base needed for pharmaceutical policym...

  2. The productive techniques and constitutive effects of 'evidence-based policy' and 'consumer participation' discourses in health policy processes.

    Science.gov (United States)

    Lancaster, K; Seear, K; Treloar, C; Ritter, A

    2017-03-01

    For over twenty years there have been calls for greater 'consumer' participation in health decision-making. While it is recognised by governments and other stakeholders that 'consumer' participation is desirable, barriers to meaningful involvement nonetheless remain. It has been suggested that the reifying of 'evidence-based policy' may be limiting opportunities for participation, through the way this discourse legitimates particular voices to the exclusion of others. Others have suggested that assumptions underpinning the very notion of the 'affected community' or 'consumers' as fixed and bounded 'policy publics' need to be problematised. In this paper, drawing on interviews (n = 41) with individuals closely involved in Australian drug policy discussions, we critically interrogate the productive techniques and constitutive effects of 'evidence-based policy' and 'consumer participation' discourses in the context of drug policy processes. To inform our analysis, we draw on and combine a number of critical perspectives including Foucault's concept of subjugated knowledges, the work of feminist theorists, as well as recent work regarding conceptualisations of emergent policy publics. First, we explore how the subject position of 'consumer' might be seen as enacted in the material-discursive practices of 'evidence-based policy' and 'consumer participation' in drug policy processes. Secondly, we consider the centralising power-effects of the dominant 'evidence-based policy' paradigm, and how resistance may be thought about in this context. We suggest that such interrogation has potential to recast the call for 'consumer' participation in health policy decision-making and drug policy processes. Copyright © 2017 Elsevier Ltd. All rights reserved.

  3. Policy processes and decision making of environmental policy in Great Britain and France. Vol. 1

    International Nuclear Information System (INIS)

    Schreiber, H.

    1991-01-01

    Research of central aspects of British environmental policy. This report concentrates on the role of the constitutional system of environmental policy, on the evaluation of a growing of 'Green Policy' in Great Britain, on the central problems of environmental policy and finally on the role of international environmental policy for Great Britain and Great Britain's role in international environmental activities. Beyond that this report contains a presentation of the state of the British environment (Pollution: Air, Water, Waste, Soil; Radioactivity and Noise). (orig.) With 205 refs., 18 tabs., 14 figs [de

  4. Gas Metal Arc Welding and Flux-Cored Arc Welding. Third Edition. Teacher Edition [and] Student Edition [and] Student Workbook.

    Science.gov (United States)

    Knapp, John; Harper, Eddie

    This packet, containing a teacher's edition, a student edition, and a student workbook, introduces students to high deposition welding and processes for "shielding" a weld. In addition to general information, the teacher edition consists of introductory pages and teacher pages, as well as unit information that corresponds to the…

  5. Cluster editing

    DEFF Research Database (Denmark)

    Böcker, S.; Baumbach, Jan

    2013-01-01

    . The problem has been the inspiration for numerous algorithms in bioinformatics, aiming at clustering entities such as genes, proteins, phenotypes, or patients. In this paper, we review exact and heuristic methods that have been proposed for the Cluster Editing problem, and also applications...

  6. genome editing

    Indian Academy of Sciences (India)

    2016-02-11

    Feb 11, 2016 ... What history tells us. XL. The success story of the expression 'genome editing'. MICHEL MORANGE. Centre Cavaillès, République des Savoirs: Lettres, Sciences, Philosophie USR 3608, Ecole. Normale Supérieure, 29 Rue d'Ulm, 75230, Paris Cedex 05, France. (Fax, 33-144-323941; Email, ...

  7. What factors in the policy-making process determine the priority given to a policy issue?

    Directory of Open Access Journals (Sweden)

    Erisa Xhixho

    2015-03-01

    Full Text Available Agenda setting is the process by which problems and alternative solutions gain or lose public attention (Birkland T. (2007, p.63; Werner J. and Wegrich K. (2007, p.46.. The main factor that determine an issue that it could become a priority, drawing the attention of decision makers, the public, reaching for it to become part of the agenda are: “Window of Opportunity”, which is a strategy used by less powerful groups, which are benefiting from the fact that powerful groups in certain situations may lose control of the agenda, they manage this circumstances to make their case to the priority. Another factor are the “Focus Event” that emphasizes the fact that unexpected events that shock the public opinion, as were the cases of corruption of officials, case “Snowden” or 11 September in the USA, affecting an issue that directly lead the decision-making agenda. Advocacy coalitions, is a form that use less powerful groups by joining on the basis of certain principles, values, beliefs they have about a particular issue. This alliance of values, resources and coordination of actions helps to advance the issue becoming a priority. “Venue shop” as a factor that aims to reach groups through institutions, be heard, be able to attract the attention of decision makers, also using the media as a very important factor nowadays for sensitizing public opinion on the issue and influence in order to become a priority issue. “Policy network” has come as a need of developing a relationship between government and the private sector, thus forming a power dependency relationship mainly the exchange of resources and thereby influencing the political agenda on particular issues. Therefore in this article I will try to argue that these factors affect in various ways becoming determinant that the issue be the priority on the decision agenda. Also, I can say that after the development of the analysis, I think that the two factors have a greater influence

  8. Application of Management Policies in the Processing of Member ...

    African Journals Online (AJOL)

    The study found a significant proportion of the respondents (NSSF staff) were generally familiar with the concept of management policy applied by NSSF. Secondly, management policies applied by NSSF included: customer service and corporate imaging (.727), change management (.605), human resource capacity ...

  9. Engaging Effectively in the Policy-Making Process

    Science.gov (United States)

    McLaughlin, Virginia L.; West, Jane E.; Anderson, Jeffrey A.

    2016-01-01

    Current political polarization and competing priorities complicate development of sound education policy. Particularly troubling is the disconnect between research and policy, as decision makers rely more on the work of think tanks and advocacy groups than the knowledge base of the profession. The mismatch between higher education and policy…

  10. Facilitating participatory processes for policy change in natural ...

    African Journals Online (AJOL)

    Mo

    an open and participatory policy and decision -making at the lower .... people who are open minded and who believe in the success of change ..... Figure 3: Policy Task Force Critical Triangle. Source: Adapted form Catacutan et al. (2001). Farmers and local organisations. R&D Facilitators. Decentralized local government.

  11. Vanuatu Education Policy Post-2015: "Alternative", Decolonising Processes for "Development"

    Science.gov (United States)

    McCormick, Alexandra

    2016-01-01

    This article is based on ongoing research in Vanuatu and the wider Pacific. It maps multilevel roles that education and development policy actors, and civil societies in particular, have increasingly been playing in official education and development policy activities. Most recently this has been in relation to the "post-2015" agendas…

  12. Road pricing policy process : The interplay between policy actors, the media and public

    NARCIS (Netherlands)

    Ardiç, O.

    2015-01-01

    Although road pricing policies are generally seen as an effective measure to deal with transport related problems (e.g. congestion), the number of implemented road pricing schemes is relatively limited. The thesis aims to gain insights into complex interplay between policy actors, media and public

  13. Policy Democracy: Social and Material Participation in Biodiesel Policy-Making Processes in India

    NARCIS (Netherlands)

    de Hoop, E.; Arora, Saurabh

    2017-01-01

    Following its 2003 biodiesel mission, the Indian national government released its controversial policy on biodiesel in December 2009. Viewing the policy as a set of propositions that have been progressively assembled and constituted by many voices, we study its making on the basis of 72 qualitative

  14. Policy Making Processes with Respect to Teacher Education in Finland and Norway

    Science.gov (United States)

    Afdal, Hilde Wagsas

    2013-01-01

    This article examines policy making processes in the area of teacher education (TE) in Finland and Norway. Particular attention is given to the roles different actors play in these processes and the potential effects of their involvement on the TE programs in the two countries. Contemporary policy processes are analyzed through a set of interviews…

  15. Public policy processes and getting physical activity into Alberta's urban schools.

    Science.gov (United States)

    Gladwin, Catherine P; Church, John; Plotnikoff, Ronald C

    2008-01-01

    Public policies impact the amount of physical activity (PA) that children receive at school. These policies are of interest because overweight and obesity among Canadian children have grown at significant rates, and increasing PA among children is one way to reverse this trend. This research investigates the public policy processes that have resulted in Alberta's education system adopting in-school daily physical activity (DPA) and not supporting walk-to-school (WTS) initiatives. Using the policy process described by Kingdon and others as a conceptual framework, this research reviews literature and documents on public policy relating to PA in schools and interviews key individuals (N = 20) to identify the policy-related facilitators and barriers in Alberta, Canada to increasing PA in school-aged children. DPA was mandated because Kingdon's three policy streams (problem, solution and politics) became joined or linked. DPA was the most viable solution because literature supports and teachers believe in the educational benefits of PA. As well, a physician with personal beliefs about the benefits of PA became the minister of education and coupled the solution with the political stream through his ministerial power. Reasons that WTS programs have not become school or health policy include advocacy led by politically weak organizations, lack of a supportive policy entrepreneur and poor saliency among educators. This research illuminates the inner workings of the policy process shaping PA in schools, identifying the unseen forces of the policy process that move issues forward. The findings provide valuable insight for building other healthy public policies.

  16. RNA editing machinery in plant organelles.

    Science.gov (United States)

    Yan, Junjie; Zhang, Qunxia; Yin, Ping

    2018-02-01

    RNA editing is a type of post-transcriptional modification that includes nucleotide insertion/deletion or conversion. Different categories of RNA editing have been widely observed in distinct RNAs from divergent organisms. In flowering plants, RNA editing usually alters cytidine to uridine in plastids and mitochondria, playing important roles in various plant developmental processes, including organelle biogenesis, adaptation to environmental changes, and signal transduction. Numerous studies have demonstrated that a number of factors are involved in plant RNA editing, such as pentatricopeptide repeat (PPR) proteins, multiple organelle RNA editing factors (MORF, also known as RIP), organelle RNA recognition motif (ORRM) containing proteins, protoporphyrinogen IX oxidase 1 (PPO1) and organelle zinc finger 1 (OZ1). These factors play diverse roles in plant RNA editing due to their distinct characteristics. In this review, we discuss the functional roles of the individual editing factors and their associations in plant RNA editing.

  17. What shapes research impact on policy? Understanding research uptake in sexual and reproductive health policy processes in resource poor contexts.

    Science.gov (United States)

    Sumner, Andy; Crichton, Jo; Theobald, Sally; Zulu, Eliya; Parkhurst, Justin

    2011-06-16

    Assessing the impact that research evidence has on policy is complex. It involves consideration of conceptual issues of what determines research impact and policy change. There are also a range of methodological issues relating to the question of attribution and the counter-factual. The dynamics of SRH, HIV and AIDS, like many policy arenas, are partly generic and partly issue- and context-specific. Against this background, this article reviews some of the main conceptualisations of research impact on policy, including generic determinants of research impact identified across a range of settings, as well as the specificities of SRH in particular. We find that there is scope for greater cross-fertilisation of concepts, models and experiences between public health researchers and political scientists working in international development and research impact evaluation. We identify aspects of the policy landscape and drivers of policy change commonly occurring across multiple sectors and studies to create a framework that researchers can use to examine the influences on research uptake in specific settings, in order to guide attempts to ensure uptake of their findings. This framework has the advantage that distinguishes between pre-existing factors influencing uptake and the ways in which researchers can actively influence the policy landscape and promote research uptake through their policy engagement actions and strategies. We apply this framework to examples from the case study papers in this supplement, with specific discussion about the dynamics of SRH policy processes in resource poor contexts. We conclude by highlighting the need for continued multi-sectoral work on understanding and measuring research uptake and for prospective approaches to receive greater attention from policy analysts.

  18. Europeanization in VET Policy as a Process of Reshaping the Educational Space

    Directory of Open Access Journals (Sweden)

    Krista Loogma

    2016-04-01

    Full Text Available The EU represents a transforming educational space, where national and supranational boundaries in educational governance are becoming blurred. The EU has become an  important actor in educational governance and an important arena for policy learning and transfer. This paper explores how the process of reshaping the educational space manifests itself in the process of the Europeanization of VET policy in the case of Estonia. In Estonia, this process was followed by the growth of executive VET institutions and has developed from rather uncritical initial policy transfer to more active learning from the EU, although conformism can still be seen in cases of the introduction of standardizing policy tools.

  19. Educational management and policy in the globalization process

    Directory of Open Access Journals (Sweden)

    Myriam Feldfeber

    2007-09-01

    Full Text Available This work analyzes the main orientation of educational policies designed and implemented in the region within the so called “second generation state reforms”, in a context of growing inequality, fragmentation and social polarization. These reforms have been based, on the one hand, on the Knowledge Society Paradigm and the demand for competitive insertion in the global economy, and on the other, on strategies for poverty reduction and containment aimed at guaranteeing democratic governance in Latin American countries. In this vein, new forms of government and management of educational systems have been designed and implemented, that can be analyzed as new ways to regulate educational policy and action.

  20. Influenza vaccination policy-making processes in France and The Netherlands: framework and determinants.

    NARCIS (Netherlands)

    Silva, M.L.; Perrier, L.; Paget, W.J.; Mosnier, A.; Buthion, V.; Cohen, J.M.; Späth, H.M.

    2016-01-01

    Objectives: Target groups for seasonal influenza vaccination are nationally defined based on several factors. However, few studies have explored the policy-making processes at the country-level. We investigated key differences in the policy-making process for the development of vaccination

  1. Mental health policy process: a comparative study of Ghana, South Africa, Uganda and Zambia

    Directory of Open Access Journals (Sweden)

    Kigozi Fred

    2010-08-01

    Full Text Available Abstract Background Mental illnesses are increasingly recognised as a leading cause of disability worldwide, yet many countries lack a mental health policy or have an outdated, inappropriate policy. This paper explores the development of appropriate mental health policies and their effective implementation. It reports comparative findings on the processes for developing and implementing mental health policies in Ghana, South Africa, Uganda and Zambia as part of the Mental Health and Poverty Project. Methods The study countries and respondents were purposively selected to represent different levels of mental health policy and system development to allow comparative analysis of the factors underlying the different forms of mental health policy development and implementation. Data were collected using semi-structured interviews and document analysis. Data analysis was guided by conceptual framework that was developed for this purpose. A framework approach to analysis was used, incorporating themes that emerged from the data and from the conceptual framework. Results Mental health policies in Ghana, South Africa, Uganda and Zambia are weak, in draft form or non-existent. Mental health remained low on the policy agenda due to stigma and a lack of information, as well as low prioritisation by donors, low political priority and grassroots demand. Progress with mental health policy development varied and respondents noted a lack of consultation and insufficient evidence to inform policy development. Furthermore, policies were poorly implemented, due to factors including insufficient dissemination and operationalisation of policies and a lack of resources. Conclusions Mental health policy processes in all four countries were inadequate, leading to either weak or non-existent policies, with an impact on mental health services. Recommendations are provided to strengthen mental health policy processes in these and other African countries.

  2. Policy development: a more formal systems approach process

    CSIR Research Space (South Africa)

    Greeff, AP

    2011-09-01

    Full Text Available is suggested. The similarity between the classical systems approach and typical current policy development life-cycles are striking. The rigorous systems approach, as often used in Systems Engineering projects, could be adapted, and thus provide the rigour...

  3. DEAH-RHA helicase•Znf cofactor systems in kinetoplastid RNA editing and evolutionarily distant RNA processes

    Science.gov (United States)

    Cruz-Reyes, Jorge; Mooers, Blaine H.M.; Abu-Adas, Zakaria; Kumar, Vikas; Gulati, Shelly

    2016-01-01

    Multi-zinc finger proteins are an emerging class of cofactors in DEAH-RHA RNA helicases across highly divergent eukaryotic lineages. DEAH-RHA helicase•zinc finger cofactor partnerships predate the split of kinetoplastid protozoa, which include several human pathogens, from other eukaryotic lineages 100–400 Ma. Despite a long evolutionary history, the prototypical DEAH-RHA domains remain highly conserved. This short review focuses on a recently identified DEAH-RHA helicase•zinc finger cofactor system in kinetoplastid RNA editing, and its potential functional parallels with analogous systems in embryogenesis control in nematodes and antivirus protection in humans. PMID:27540585

  4. A future scenario of the global regulatory landscape regarding genome-edited crops

    Science.gov (United States)

    Araki, Motoko

    2017-01-01

    ABSTRACT The global agricultural landscape regarding the commercial cultivation of genetically modified (GM) crops is mosaic. Meanwhile, a new plant breeding technique, genome editing is expected to make genetic engineering-mediated crop breeding more socially acceptable because it can be used to develop crop varieties without introducing transgenes, which have hampered the regulatory review and public acceptance of GM crops. The present study revealed that product- and process-based concepts have been implemented to regulate GM crops in 30 countries. Moreover, this study analyzed the regulatory responses to genome-edited crops in the USA, Argentina, Sweden and New Zealand. The findings suggested that countries will likely be divided in their policies on genome-edited crops: Some will deregulate transgene-free crops, while others will regulate all types of crops that have been modified by genome editing. These implications are discussed from the viewpoint of public acceptance. PMID:27960622

  5. A future scenario of the global regulatory landscape regarding genome-edited crops.

    Science.gov (United States)

    Ishii, Tetsuya; Araki, Motoko

    2017-01-02

    The global agricultural landscape regarding the commercial cultivation of genetically modified (GM) crops is mosaic. Meanwhile, a new plant breeding technique, genome editing is expected to make genetic engineering-mediated crop breeding more socially acceptable because it can be used to develop crop varieties without introducing transgenes, which have hampered the regulatory review and public acceptance of GM crops. The present study revealed that product- and process-based concepts have been implemented to regulate GM crops in 30 countries. Moreover, this study analyzed the regulatory responses to genome-edited crops in the USA, Argentina, Sweden and New Zealand. The findings suggested that countries will likely be divided in their policies on genome-edited crops: Some will deregulate transgene-free crops, while others will regulate all types of crops that have been modified by genome editing. These implications are discussed from the viewpoint of public acceptance.

  6. Political processes and variation in renewable energy policies between U.S. states

    Science.gov (United States)

    Vasseur, Michael

    Over the past forty years federal efforts at renewable energy policy in the United States have been fragmented and are largely stalled. This is much different from U.S. states, which enact a diverse array of renewable energy policies. What factors explain this subnational variation? Addressing this question requires moving past the standard model of binary policy adoption that dominates studies of renewable energy policy. In its place I provide analyses of multifaceted policy outcomes, and also include predictors from a more inclusive view of politics than the standard economic and political interest factors. These additions to the standard energy policy model shed light not just on when states take policy action, but also on the content of the policies states ultimately adopt. In this dissertation I argue that different combinations of state-level political and economic characteristics influence policy adoption and policy content, a fact that is obscured by analysis of only binary policy action. I demonstrate this through three empirical projects that utilize an original longitudinal dataset and a variety of quantitative methods. The first project examines the diffusion of two varieties of a single regulatory policy instrument within a political context. I demonstrate that, contrary to most diffusion studies, policy adoption should be thought of as a multifaceted process, with separate factors determining the impetus for action and others shaping the content of the policy. My second project examines the role of economic, political, institutional, and cultural factors on a state's portfolio of policies. This work extends findings from prior literature on tax policies and incorporates institutional and cultural accounts of policy adoption into the study of renewable energy policy. I show that state economic and political factors, the predictors in traditional energy policy models, predict policy action but not policy content. Instead it is a state's cultural context

  7. Australia's Health Star Rating policy process: Lessons for global policy-making in front-of-pack nutrition labelling.

    Science.gov (United States)

    Kumar, Medha; Gleeson, Deborah; Barraclough, Simon

    2017-11-12

    This study explored factors that shaped the development of Australia's Health Star Rating system for front-of-pack labelling (FoPL) on packaged foods and whether insights could be drawn from this experience to inform the development of global FoPL standards. Ten individual semi-structured interviews were conducted with public health or consumer advocates, academics in the field of nutrition labelling and policy, a food industry employee, and Australian public servants. Thematic analysis was undertaken, guided by Kingdon's Multiple Streams Framework, to identify factors which shaped Australian and international FoPL policy processes. Senior Australian bureaucrats played the policy entrepreneur role to facilitate the development of the Health Star Rating system. The public health and consumer advocacy groups formed an alliance to counter-balance the influence of the food industry in the Health Star Rating development process. Public health and consumer groups have less influence at Codex Alimentarius, where policy-making is constrained by political alliances and consensus voting structures. Strong leadership, policy entrepreneurship and a coherent alliance between public health and consumer groups enabled the development of a FoPL system in Australia and could contribute to advancing FoPL standards at the international level. © 2017 Dietitians Association of Australia.

  8. Dissolving decision making? Models and their roles in decision-making processes and policy at large.

    Science.gov (United States)

    Zeiss, Ragna; van Egmond, Stans

    2014-12-01

    This article studies the roles three science-based models play in Dutch policy and decision making processes. Key is the interaction between model construction and environment. Their political and scientific environments form contexts that shape the roles of models in policy decision making. Attention is paid to three aspects of the wider context of the models: a) the history of the construction process; b) (changes in) the political and scientific environments; and c) the use in policy processes over longer periods of time. Models are more successfully used when they are constructed in a stable political and scientific environment. Stability and certainty within a scientific field seems to be a key predictor for the usefulness of models for policy making. The economic model is more disputed than the ecology-based model and the model that has its theoretical foundation in physics and chemistry. The roles models play in policy processes are too complex to be considered as straightforward technocratic powers.

  9. International Processes of Education Policy Formation: An Analytic Framework and the Case of Plan 2021 in El Salvador

    Science.gov (United States)

    Edwards, D. Brent, Jr.

    2013-01-01

    This article uses multiple perspectives to frame international processes of education policy formation and then applies the framework to El Salvador's Plan 2021 between 2003 and 2005. These perspectives are policy attraction, policy negotiation, policy imposition, and policy hybridization. Research reveals that the formation of Plan 2021 was the…

  10. Using research evidence to reframe the policy debate around mental illness and guns: process and recommendations.

    Science.gov (United States)

    McGinty, Emma E; Frattaroli, Shannon; Appelbaum, Paul S; Bonnie, Richard J; Grilley, Anna; Horwitz, Joshua; Swanson, Jeffrey W; Webster, Daniel W

    2014-11-01

    Recent mass shootings have prompted a national dialogue around mental illness and gun policy. To advance an evidence-informed policy agenda on this controversial issue, we formed a consortium of national gun violence prevention and mental health experts. The consortium agreed on a guiding principle for future policy recommendations: restricting firearm access on the basis of certain dangerous behaviors is supported by the evidence; restricting access on the basis of mental illness diagnoses is not. We describe the group's process and recommendations.

  11. The legacy of French colonial policy on the nation building process ...

    African Journals Online (AJOL)

    It is against this background that this article examines France's colonial policy in Chad and its impact on nation building process before the outbreak of the country's civil war in the period shortly after independence. The essay argues that France's policies of “useful” and “useless Chad” was greatly responsible for the ...

  12. Dissolving decision making? : Models and their roles in decision-making processes and policy at large

    NARCIS (Netherlands)

    Zeiss, Ragna; van Egmond, S.

    2014-01-01

    This article studies the roles three science-based models play in Dutch policy and decision making processes. Key is the interaction between model construction and environment. Their political and scientific environments form contexts that shape the roles of models in policy decision making.

  13. Policy and Advocacy Concepts and Processes: Innovative Content in Early Childhood Teacher Education

    Science.gov (United States)

    Hollingsworth, Heidi L.; Knight-McKenna, Mary; Bryan, Ren

    2016-01-01

    Knowledge and skills regarding policy and advocacy are important expectations for today's early childhood workforce, yet policy and advocacy content and processes have not traditionally been emphasized in teacher preparation programmes. This article describes an innovative undergraduate course that goes beyond traditional foci on developmental…

  14. Revitalizing REDD+ Policy Processes in Vietnam: The Roles of State and Non-State Actors

    Directory of Open Access Journals (Sweden)

    Thu Ba Huynh

    2017-02-01

    Full Text Available Vietnam was one of the first countries to introduce the National REDD+ (Reduced Emissions from Deforestation and Forest Degradation Action Program in 2012. The country has recently revised the Program to aim for a more inclusive 2016–2020 strategy and a vision to 2030. This study explores how Vietnam policy actors view REDD+ policy development and their influence in these processes. The results can contribute to the discussion on how policy actors can effectively influence policy processes in the evolving context of REDD+ and in the types of political arrangements represented in Vietnam. We examined the influence of state and non-state actors on the 2012 National REDD+ Action Program (NRAP processes, and explored factors that may have shaped this influence, using a combination of document analysis and semi-structured interviews with 81 policy actors. It was found that non-state actors in REDD+ are still on the periphery of decision making, occupying “safe” positions, and have not taken either full advantage of their capacities, or of recent significant changes in the contemporary policy environment, to exert stronger influence on policy. We suggest that REDD+ policy processes in Vietnam need to be revitalized with key actors engaging collectively to promote the possibilities of REDD+ within a broader view of social change that reaches beyond the forestry sector.

  15. Understanding the process of establishing a food and nutrition policy: the case of Slovenia.

    Science.gov (United States)

    Kugelberg, Susanna; Jönsson, Kristina; Yngve, Agneta

    2012-09-01

    There has been an increasing effort across Europe to develop national policies in food and nutrition during the last decade. However, little is known about how public health nutrition issues get on the public health agenda and the roles individuals have when these agendas are being set. The aims of this study were to scrutinise the development process of the Slovenian national food and nutrition policy, and to identify the roles and functions of individuals who have contributed to that process. This study undertook a qualitative approach. Data collection included 18 semi-structured interviews between 2007 and 2011, and grey and scientific literature search. Text analysis was based on Kingdon's streams model, which involved highlighting the relationship between problem identification, policy solutions and political opportunities. Data were coded to identify the roles and functions of individuals participating in the agenda-setting process. The analysis showed that the opportunity for the Slovenian food and nutrition policy to be developed was largely explained by a change in political circumstances, namely the accession of Slovenia to the European Union and the Common Agricultural Policy. Individuals with experience in policy development were identified because of their analytical, strategic and policy entrepreneurial skills. The analyst was responsible for communicating the key nutrition issues to policy-makers, the strategist joined international networks and promoted policy solutions from international experts including the World Health Organization, and the policy entrepreneur took advantage of the political situation to enlist the participation of previous opponents to a national nutrition policy. This study found that individuals, their roles and skills, played an important role in the development of the Slovenian National Food and Nutrition Policy. The roles and functions of these individuals, which are identified in this study, may assist future endeavours

  16. Technical editing of research reports in biomedical journals.

    Science.gov (United States)

    Wager, Elizabeth; Middleton, Philippa

    2008-10-08

    Most journals try to improve their articles by technical editing processes such as proof-reading, editing to conform to 'house styles', grammatical conventions and checking accuracy of cited references. Despite the considerable resources devoted to technical editing, we do not know whether it improves the accessibility of biomedical research findings or the utility of articles. This is an update of a Cochrane methodology review first published in 2003. To assess the effects of technical editing on research reports in peer-reviewed biomedical journals, and to assess the level of accuracy of references to these reports. We searched The Cochrane Library Issue 2, 2007; MEDLINE (last searched July 2006); EMBASE (last searched June 2007) and checked relevant articles for further references. We also searched the Internet and contacted researchers and experts in the field. Prospective or retrospective comparative studies of technical editing processes applied to original research articles in biomedical journals, as well as studies of reference accuracy. Two review authors independently assessed each study against the selection criteria and assessed the methodological quality of each study. One review author extracted the data, and the second review author repeated this. We located 32 studies addressing technical editing and 66 surveys of reference accuracy. Only three of the studies were randomised controlled trials. A 'package' of largely unspecified editorial processes applied between acceptance and publication was associated with improved readability in two studies and improved reporting quality in another two studies, while another study showed mixed results after stricter editorial policies were introduced. More intensive editorial processes were associated with fewer errors in abstracts and references. Providing instructions to authors was associated with improved reporting of ethics requirements in one study and fewer errors in references in two studies, but no

  17. Transformation Directions of the Financial Policy in the Process of Stabilisation of the Ukrainian Economy

    Directory of Open Access Journals (Sweden)

    Petrushevska Viktoriya V.

    2013-11-01

    Full Text Available The goal of the article is consideration of theoretical provisions with respect to the state financial policy. The article considers the role of the financial policy in ensuring stabilisation of the Ukrainian financial system. It presents conceptual provisions regarding main goals, mechanisms and instruments of the stabilisation financial policy of the state. It develops economic indicators of its efficiency. The use of indicators of economic efficiency of the stabilisation financial policy by the bodies of state authority in their practical activity would provide the society with a possibility to assess expediency of measures of this policy increasing its efficiency and decreasing criticism at the government. A necessary direction of achievement of effectiveness and efficiency of the stabilisation financial policy is taking into consideration interests of all social groups (population, entrepreneurs, financial institutes and companies, etc. by the bodies of state authority in the process of its development and realisation.

  18. 32 CFR 507.18 - Processing complaints of alleged breach of policies.

    Science.gov (United States)

    2010-07-01

    ... Program § 507.18 Processing complaints of alleged breach of policies. The Institute of Heraldry may revoke... Institute of Heraldry, 9325 Gunston Road, Room S-112, Fort Belvoir, VA 22060-5579 (hereinafter referred to...

  19. Experiences with a dialogue process between policy makers and global modellers

    International Nuclear Information System (INIS)

    Van Daalen, C.E.; Thissen, W.A.H.; Berk, M.M.

    1998-01-01

    Between 1995 and 1997, a series of five workshops, henceforth called the Delft process, took place with the aim to explore and enhance use of the IMAGE 2 model to support international climate negotiations. The IMAGE 2 model is a multi-disciplinary, integrated model designed to simulate the dynamics of the global society-biosphere-climate system. The workshops facilitated a dialogue between policy makers and scientists involved in the development and applications of the IMAGE 2 model. In this way, policy makers would benefit from the policy makers on how to improve the policy relevance of the IMAGE 2 model. The evaluation at the end of the workshop series showed that participants have used information from the workshop at international negotiation conferences and in preparation of policy documents. The process shows that creating a forum for direct science-policy interactions can be very useful and productive, and has confirmed the importance of creating an open and constructive atmosphere between policy makers, and between policy makers and analysts, to enhance utilisation of scientific knowledge. The authors' analysis also suggests that many factors have to be 'in the right position at the right time and place' to achieve such a success, and that it is difficult to prevent the occurrence of biases in processes like this. 33 refs

  20. Energy shocks, crises and the policy process: A review of theory and application

    International Nuclear Information System (INIS)

    Grossman, Peter Z.

    2015-01-01

    What motivates changes in energy policy? Typically, the process begins with a notable exogenous event, a shock. Often, the shock leads to what is perceived to be a crisis. This review essay surveys theories of crisis policymaking from the social science literature and considers their application to changes in energy policy. Two cases — one from the U.S., the other from Germany — are examined in more detail from the standpoint of the theories discussed. Suggestions are made for improving energy policy analysis in the future. - Highlights: • An analysis of the idea of “crisis” and its application to energy. • A review of theories and models of the policy process and of policy change. • Theory applied to two energy cases. • Suggestion as to how the analysis of energy policymaking might be approached in the future

  1. Optimal dividend policies with transaction costs for a class of jump-diffusion processes

    DEFF Research Database (Denmark)

    Hunting, Martin; Paulsen, Jostein

    2013-01-01

    his paper addresses the problem of finding an optimal dividend policy for a class of jump-diffusion processes. The jump component is a compound Poisson process with negative jumps, and the drift and diffusion components are assumed to satisfy some regularity and growth restrictions. Each dividend......-tailed distributions, the optimal policy is a simple lump sum policy, that is, when assets are equal to or larger than an upper barrier u¯∗, they are immediately reduced to a lower barrier u−∗ through a dividend payment. The case with K=0 is also investigated briefly, and the optimal policy is shown to be a reflecting...... barrier policy for the same light-tailed class. Methods to numerically verify whether a simple lump sum barrier strategy is optimal for any jump distribution are provided at the end of the paper, and some numerical examples are given....

  2. Health policy evolution in Lao People's Democratic Republic: context, processes and agency.

    Science.gov (United States)

    Jönsson, Kristina; Phoummalaysith, Bounfeng; Wahlström, Rolf; Tomson, Göran

    2015-05-01

    During the last 20 years Lao People's Democratic Republic has successfully developed and adopted some 30 health policies, strategies, decrees and laws in the field of health. Still, the implementation process remains arduous. This article aims at discussing challenges of health policy development and effective implementation by contextualizing the policy evolution over time and by focusing particularly on the National Drug Policy and the Health Care Law. Special attention is given to the role of research in policymaking. The analysis was guided by the conceptual framework of policy context, process, content and actors, combined with an institutional perspective, and showed that effective implementation of a health policy is highly dependent on both structures and agency of those involved in the policy process. The National Drug Policy was formulated and adopted in a short period of time in a resource-scarce setting, but with dedicated policy entrepreneurs and support of concerned international collaborators. Timely introduction of operational health systems research played a crucial role to support the implementation, as well as the subsequent revision of the policy. The development of the Health Care Law took several years and once adopted, the implementation was delayed by institutional legacies and issues concerning the choice of institutional design and financing, despite strong support of the law among the policymakers. Among many factors, timing of the implementation appeared to be of crucial importance, in combination with strong leadership. These two examples show that more research, that problematizes the complex policy environment in combination with improved communication between researchers and policymakers, is necessary to inform about measures for effective implementation. A way forward can be to strengthen the domestic research capacity and the international research collaboration regionally as well as globally. Published by Oxford University Press

  3. Exploring maintenance policy selection using the Analytic Hierarchy Process; An application for naval ships

    International Nuclear Information System (INIS)

    Goossens, Adriaan J.M.; Basten, Rob J.I.

    2015-01-01

    In this paper we investigate maintenance policy selection (MPS) through the use of the Analytic Hierarchy Process (AHP). A maintenance policy is a policy that dictates which parameter triggers a maintenance action. In practice, selecting the right maintenance policy appears to be a difficult decision. We investigate MPS for naval ships, but our results have wider applicability. For our study we cooperate with the owner and operator of the ships, as well as with a shipbuilder and an original equipment manufacturer of naval ships. We apply a structured five step approach to obtain the relevant criteria that may make one policy preferable over another. The criteria are drawn from both literature and a series of interviews at several navy related companies and are structured into a hierarchy of criteria usable with the AHP. Additionally, we organize three workshops at the three different companies to test the AHP-based MPS approach in practice. We conclude that the AHP is well suited for maintenance policy selection in this broad setting, and that it provides a structured and detailed approach for MPS. Adding to that, it facilitates discussions during and after the sessions, creating a better understanding of the policy selection process. - Highlights: • We use the Analytic Hierarchy Process (AHP) for maintenance policy selection (MPS). • Using both interviews and case studies from the literature, we construct a hierarchy. • In sessions at 3 companies, we find that 1 hierarchy can be used for multiple assets. • The AHP creates a better understanding of the maintenance policy selection process. • Our work is on naval ships, but our approach and findings have wider applicability

  4. Basic Wiring. Third Edition. Teacher Edition [and] Student Edition.

    Science.gov (United States)

    Kaltwasser, Stan; Flowers, Gary; Blasingame, Don; Batson, Larry; Ipock, Dan; Carroll, Charles; Friesen, Wade; Fleming, Glenn

    This publication contains both a teacher edition and a student edition of materials for a foundation course in an electrical wiring program. The course introduces basic concepts and skills that are prerequisites to residential wiring and commercial and industrial wiring courses. The contents of the materials are tied to measurable and observable…

  5. Diesel Technology: Introduction. Teacher Edition [and] Student Edition. Second Edition.

    Science.gov (United States)

    Joerschke, John D.; Eichhorn, Lane

    This complete teacher edition of a diesel technology course consists of introductory pages, teacher pages, and the student edition. The introductory pages provide these tools: training and competency profile; National Automotive Technicians Education Foundation Crosswalk; instructional/task analysis; basic skills icons and classifications; basic…

  6. Optimum temperature policy for sorption enhanced steam methane reforming process for hydrogen production

    Energy Technology Data Exchange (ETDEWEB)

    Retnamma, Rajasree [National Laboratory of energy and Geology (LNEG), Lisbon (PT). Energy Systems Modeling and Optimization Unit (UMOSE); Ravi Kumar, V.; Kulkarni, B.D. [National Chemical Laboratory, Pune (India). Chemical Engineering and Process Development

    2010-07-01

    Sorption enhanced steam methane reforming (SE-SMR) process offers high potential for producing H{sub 2} in fuel cell applications compared to conventional catalytic steam methane reforming (SMR) process. The reactor temperature can significantly affect the performance of the SE-SMR reaction and simultaneous adsorption behavior of CO{sub 2}. Determination of an optimal temperature policy in SE-SMR reactor is therefore an important optimization issue. Multi-stage operation is a possible way to implement optimum temperature policies. In the present work, simulation study has been carried out for multi-stage operation using a mathematical model incorporating basic mechanisms operating in a fixed bed reactor with nonlinear reaction kinetic features of an SE-SMR process. Three cases were considered for implementing the multi-stage concept and the results show that increase in temperature based on a policy leads to considerable improvement in the process performance. (orig.)

  7. The Emergence and Workings of a Process View in Public Education Policy

    DEFF Research Database (Denmark)

    Pors, Justine Grønbæk; Ratner, Helene

    2017-01-01

    This article presents a study of Danish primary education policy with the purpose of exploring what is put at stake when contemporary management discourses describe the object of management as fluid and emergent processes rather than as entities, persons and things. The article examines how...... such a process view of organisation allows policy makers to imagine innovative change, but also how a process view interacts in particular ways with financial pressures and become entangled to increased performance measurements. We conclude that in this particular case, a conception of the object of management...

  8. The emergence and workings of a process view in public education policy

    DEFF Research Database (Denmark)

    Grønbæk Pors, Justine; Ratner, Helene Gad

    2017-01-01

    This article presents a study of Danish primary education policy with the purpose of exploring what is put at stake when contemporary management discourses describe the object of management as fluid and emergent processes rather than as entities, persons and things. The article examines how...... such a process view of organisation allows policy makers to imagine innovative change, but also how a process view interacts in particular ways with financial pressures and become entangled to increased performance measurements. We conclude that in this particular case, a conception of the object of management...

  9. Interactive Editing of Live Visuals

    Science.gov (United States)

    Müller, Pascal; Müller Arisona, Stefan; Schubiger-Banz, Simon; Specht, Matthias

    This paper describes novel concepts for the interactive composition of artistic real-time graphics, so-called live visuals. By establishing two fundamental techniques dealing with the structured media integration and the intrinsic design process, we significantly increase the efficiency of interactive editing in live visuals applications. First, we present a media manager that supports the user in both retrieval and utilization of automatically annotated digital media. The computer-assisted application of individual media items permits the interactive control of non-linear editing (NLE) of video in real-time. Second, we optimize the design process by introducing the design tree, which collects and organizes the artist's work in an intuitive way. Design tree operations provide interactive high-level editing methods which allow for exploration, combination, reuse, and evolution of designs before and particularly during the performance. We examined the effectiveness of our techniques on numerous long-lasting live performances from which representative examples are demonstrated.

  10. Renewable energy support policy in Spain : An analysis of the decision-making process (1994-2014)

    NARCIS (Netherlands)

    Leston, D.

    2014-01-01

    In this paper, the decision-making process behind the RE support policy will be explored in order to answer the following research questions: “why has the policy-making process been revised so many times?” and “how can such a drastic change on the RE support policy be explained?” The answer is found

  11. The application of theories of the policy process to obesity prevention: a systematic review and meta-synthesis

    OpenAIRE

    Clarke, Brydie; Swinburn, Boyd; Sacks, Gary

    2016-01-01

    Background Theories of the policy process are recommended as tools to help explain both policy stasis and change. Methods A systematic review of the application of such theoretical frameworks within the field of obesity prevention policy was conducted. A meta-synthesis was also undertaken to identify the key influences on policy decision-making. Results The review identified 17 studies of obesity prevention policy underpinned by political science theories. The majority of included studies wer...

  12. Editing Dialogics: Ethical Issues Concerning Student Contributors in Edited Collections.

    Science.gov (United States)

    Tassoni, John Paul; Tayko, Gail

    2003-01-01

    Discusses the authors' attempts to enact a process they have come to call "editing dialogics" and its relation to the Conference on College Composition and Communication's "Guidelines for the Ethical Treatment of Students and Student Writing in Composition Studies." Makes their roles explicit to expose elements of scholarly…

  13. National medicines policies – a review of the evolution and development processes

    Science.gov (United States)

    2013-01-01

    Objectives Continuous provision of appropriate medicines of assured quality, in adequate quantities, and at reasonable prices is a concern for all national governments. A national medicines policy (NMP) developed in a collaborative fashion identifies strategies needed to meet these objectives and provides a comprehensive framework to develop all components of a national pharmaceutical sector. To meet the health needs of the population, there is a general need for medicine policies based on universal principles, but nevertheless adapted to the national situation. This review aims to provide a quantitative and qualitative (describing the historical development) study of the development process and evolution of NMPs. Methods The number of NMPs and their current status has been obtained from the results of the assessment of WHO Level I indicators. The policy formulation process is examined in more detail with case studies from four countries: Sri Lanka, Australia, former Yugoslav Republic of Macedonia and South Africa. Results The number of NMPs worldwide has increased in the last 25 years with the highest proportional increase in the last 5–10 years in high-income countries. Higher income countries seem to have more NMP implementation plans available and have updated their NMP more recently. The four case studies show that the development of a NMP is a complex process that is country specific. In addition, it demonstrates that an appropriate political window is needed for the policy to be passed (for South Africa and the FYR Macedonia, a major political event acted as a trigger for initiating the policy development). Policy-making does not stop with the official adoption of a policy but should create mechanisms for implementation and monitoring. The NMPs of the FYR Macedonia and Australia provide indicators for monitoring. Conclusions To date, not all countries have a NMP since political pressure by national experts or non-governmental organizations is generally

  14. Processes of local alcohol policy-making in England: Does the theory of policy transfer provide useful insights into public health decision-making?

    Science.gov (United States)

    Gavens, Lucy; Holmes, John; Buykx, Penny; de Vocht, Frank; Egan, Matt; Grace, Daniel; Lock, Karen; Mooney, John D; Brennan, Alan

    2017-06-13

    Recent years have seen a rise in new and innovative policies to reduce alcohol consumption and related harm in England, which can be implemented by local, as opposed to national, policy-makers. The aim of this paper is to explore the processes that underpin the adoption of these alcohol policies within local authorities. In particular, it aims to assess whether the concept of policy transfer (i.e. a process through which knowledge about policies in one place is used in the development of policies in another time or place) provides a useful model for understanding local alcohol policy-making. Qualitative data generated through in-depth interviews and focus groups from five case study sites across England were used to explore stakeholder experiences of alcohol policy transfer between local authorities. The purposive sample of policy actors included representatives from the police, trading standards, public health, licensing, and commissioning. Thematic analysis was used inductively to identify key features in the data. Themes from the policy transfer literature identified in the data were: policy copying, emulating, hybridization, and inspiration. Participants described a multitude of ways in which learning was shared between places, ranging from formal academic evaluation to opportunistic conversations in informal settings. Participants also described facilitators and constraints to policy transfer, such as the historical policy context and the local cultural, economic, and bureaucratic context, which influenced whether or not a policy that was perceived to work in one place might be transferred successfully to another context. Theories of policy transfer provide a promising framework for characterising processes of local alcohol policy-making in England, extending beyond debates regarding evidence-informed policy to account for a much wider range of considerations. Applying a policy transfer lens enables us to move beyond simple (but still important) questions of

  15. Exploring health systems research and its influence on policy processes in low income countries

    Directory of Open Access Journals (Sweden)

    Syed Shamsuzzoha B

    2007-10-01

    Full Text Available Abstract Background The interface between research and policymaking in low-income countries is highly complex. The ability of health systems research to influence policy processes in such settings face numerous challenges. Successful analysis of the research-policy interface in these settings requires understanding of contextual factors as well as key influences on the interface. Future Health Systems (FHS: Innovations for Equity is a consortium conducting research in six countries in Asia and Africa. One of the three cross-country research themes of the consortium is analysis of the relationship between research (evidence and policy making, especially their impact on the poor; insights gained in the initial conceptual phase of FHS activities can inform the global knowledge pool on this subject. Discussion This paper provides a review of the research-policy interface in low-income countries and proposes a conceptual framework, followed by directions for empirical approaches. First, four developmental perspectives are considered: social institutional factors; virtual versus grassroots realities; science-society relationships; and construction of social arrangements. Building on these developmental perspectives three research-policy interface entry points are identified: 1. Recognizing policy as complex processes; 2. Engaging key stakeholders: decision-makers, providers, scientists, and communities; and 3. Enhancing accountability. A conceptual framework with three entry points to the research-policy interface – policy processes; stakeholder interests, values, and power; and accountability – within a context provided by four developmental perspectives is proposed. Potential empirical approaches to the research-policy interface are then reviewed. Finally, the value of such innovative empirical analysis is considered. Conclusion The purpose of this paper is to provide the background, conceptual framework, and key research directions for

  16. Developing New Mexico Health Care Policy: An application of the Vital Issues Process

    Energy Technology Data Exchange (ETDEWEB)

    Engi, D. [Sandia National Labs., Albuquerque, NM (United States); Icerman, L. [Icerman & Associates, Santa Fe, NM (United States)

    1995-06-01

    The Vital Issues Process, developed by the Sandia National Laboratories Strategic Technologies Department, was utilized by the Health Care Task Force Advisory Group to apply structure to their policy deliberations. By convening three expert panels, an overarching goal for the New Mexico health care system, seven desired outcomes, nine policy options, and 17 action items were developed for the New Mexico health care system. Three broadly stated evaluation criteria were articulated and used to produce relative rankings of the desired outcomes and policy options for preventive care and information systems. Reports summarizing the policy deliberations were submitted for consideration by the Health Care Task Force, a Joint Interim Committee of the New Mexico Legislature, charged with facilitating the development and implementation of a comprehensive health care delivery system for New Mexico. The Task Force reported its findings and recommendations to the Second Session of the 41st New Mexico State Legislature in January 1994.

  17. Language Editing at Astronomy & Astrophysics

    Science.gov (United States)

    Adams, J.

    2011-07-01

    In 2002, the A&A Board of Directors voted that all articles must be written in English and decided to improve the overall quality of the language in the articles with the help of a team of language editors. This article reviews the general advantages of editing the English expression and describes both the aims of this effort and its place in the full publication process. This is followed by the Guide to language editing that has been available on the Journal's website for several years now.

  18. Soil Carbon Sequestration and the Greenhouse Effect (2nd Edition)

    Science.gov (United States)

    This volume is a second edition of the book “Soil Carbon Sequestration and The Greenhouse Effect”. The first edition was published in 2001 as SSSA Special Publ. #57. The present edition is an update of the concepts, processes, properties, practices and the supporting data. All chapters are new co...

  19. Between Policies and Practices: The Challenges of Inclusive Education in Brazil

    Science.gov (United States)

    Pletsch, Marcia Denise; Mendes, Geovana Mendonça Lunardi

    2015-01-01

    This paper aims to present the second edition of the Special Education Dossier: Differences, Curriculum and Teaching and Learning Processes. We discuss policies and practices regarding the inclusive education proposal in the Basic Education context. Our starting point is the idea that we are facing a global education policy and thus many local…

  20. Off-Policy Reinforcement Learning: Optimal Operational Control for Two-Time-Scale Industrial Processes.

    Science.gov (United States)

    Li, Jinna; Kiumarsi, Bahare; Chai, Tianyou; Lewis, Frank L; Fan, Jialu

    2017-12-01

    Industrial flow lines are composed of unit processes operating on a fast time scale and performance measurements known as operational indices measured at a slower time scale. This paper presents a model-free optimal solution to a class of two time-scale industrial processes using off-policy reinforcement learning (RL). First, the lower-layer unit process control loop with a fast sampling period and the upper-layer operational index dynamics at a slow time scale are modeled. Second, a general optimal operational control problem is formulated to optimally prescribe the set-points for the unit industrial process. Then, a zero-sum game off-policy RL algorithm is developed to find the optimal set-points by using data measured in real-time. Finally, a simulation experiment is employed for an industrial flotation process to show the effectiveness of the proposed method.

  1. Europeanization in VET Policy as a Process of Reshaping the Educational Space

    Science.gov (United States)

    Loogma, Krista

    2016-01-01

    The EU represents a transforming educational space, where national and supranational boundaries in educational governance are becoming blurred. The EU has become an important actor in educational governance and an important arena for policy learning and transfer. This paper explores how the process of reshaping the educational space manifests…

  2. Policies lost in translation? Unravelling water reform processes in African waterscapes

    NARCIS (Netherlands)

    Kemerink-Seyoum, J.S.

    2015-01-01

    Since the 1980s a major change took place in public policies for water resources management. The role of governments shifted under this reform process from an emphasis on investment in the development, operation and maintenance of water infrastructure to a focus on managing water resources systems

  3. The Implementation Process of Alcohol Policies in Eight Swedish Football Clubs

    Science.gov (United States)

    Geidne, Susanna; Quennerstedt, Mikael; Eriksson, Charli

    2013-01-01

    Purpose: Alcohol stands in an ambiguous relationship to sports, and there is a common belief that participation in sports prevents alcohol consumption. Although this is not always the case, sports clubs can be important settings for health promoting alcohol policy interventions .The purpose of this paper is to explore the process of implementing…

  4. Researching International Processes of Education Policy Formation: Conceptual and Methodological Considerations

    Science.gov (United States)

    Edwards, D. Brent, Jr.

    2012-01-01

    This article elaborates one approach to conceptualizing and investigating international processes of education policy formation (IPEPF), which are dynamic, multi-level and processual in nature. This contribution is important because, although research is increasingly conducted on phenomena with such characteristics, extended discussions of how…

  5. Integrated Tales of Policies, Teaching and Teacher Education: Reflecting on an Ongoing Process

    Science.gov (United States)

    Reddy, C.

    2009-01-01

    Changing times in teacher education has been a long mantra and many changes have been occurring globally in this sector of higher education. In South Africa teacher education change has been linked to changes in the broader education processes and includes policy changes and the development of regulatory frameworks which all impacted on practice…

  6. Exploring National Environmental Policy Act processes across federal land management agencies

    Science.gov (United States)

    Marc J. Stern; Michael J. Mortimer

    2009-01-01

    Broad discretion is granted at all levels throughout federal land management agencies regarding compliance with the National Environmental Policy Act (NEPA). We explored the diversity of procedures employed in NEPA processes across four agencies, the USDA Forest Service, The USDI National Park Service and Bureau of Land Management, and the U.S. Army Corps of Engineers...

  7. Comparison of NITAG policies and working processes in selected developed countries.

    NARCIS (Netherlands)

    Ricciardi, G.W.; Toumi, M; Weil-Olivier, C.; Ruitenberg, E.J.; Danko, D; Picazo, J.; Zöllner, Y.; Poland, G.; Drummond, M

    2014-01-01

    Background: Vaccines are specific medicines characterized by two country-specific market access processes: (1) a recommendation by National Immunization Technical Advisory Group (NITAG), and (2) a funding policy decision. Objectives: The objective of this study was to compare and analyze NITAGs of

  8. Tracing the Policy Mediation Process in the Implementation of a Change in the Life Sciences Curriculum

    Science.gov (United States)

    Singh-Pillay, Asheena; Alant, Busisiwe

    2015-01-01

    This paper accounts for the enacted realities of curriculum reform in South Africa, in particular the mediation of curriculum change. Curriculum implementation is viewed as a complex networked process of transforming or mediating policy into classroom practice. The fact that curriculum implementation is seen as problematic requires attention for…

  9. Politics, policies and processes: a multidisciplinary and multimethods research programme on policies on the social determinants of health inequity in Australia.

    Science.gov (United States)

    Baum, Fran; Friel, Sharon

    2017-12-21

    The development and implementation of multisectoral policy to improve health and reduce health inequities has been slow and uneven. Evidence is largely focused on the facts of health inequities rather than understanding the political and policy processes. This 5-year funded programme of research investigates how these processes could function more effectively to improve equitable population health. The programme of work is organised in four work packages using four themes (macroeconomics and infrastructure, land use and urban environments, health systems and racism) related to the structural drivers shaping the distribution of power, money and resources and daily living conditions. Policy case studies will use publicly available documents (policy documents, published evaluations, media coverage) and interviews with informants (policy-makers, former politicians, civil society, private sector) (~25 per case). NVIVO software will be used to analyse the documents to see how 'social and health equity' is included and conceptualised. The interview data will include qualitative descriptive and theory-driven critical discourse analysis. Our quantitative methodological work assessing the impact of public policy on health equity is experimental that is in its infancy but promises to provide the type of evidence demanded by policy-makers. Our programme is recognising the inherently political nature of the uptake, formulation and implementation of policy. The early stages of our work indicate its feasibility. Our work is aided by a Critical Policy Reference Group. Multiple ethics approvals have been obtained with the foundation approval from the Social and Behavioural Ethics Committee, Flinders University (Project No: 6786).The theoretical, methodological and policy engagement processes established will provide improved evidence for policy-makers who wish to reduce health inequities and inform a new generation of policy savvy knowledge on social determinants. © Article author

  10. On applications of excess level processes to (N,D-policy bulk queueing systems

    Directory of Open Access Journals (Sweden)

    Jewgeni H. Dshalalow

    1996-01-01

    Full Text Available The paper deals with queueing systems in which N- and D-policies are combined into one. This means that an idle or vacationing server will resume his service if the queueing or workload process crosses some specified fixed level N or D, respectively. For the proposed (N,D-policy we study the queueing processes in models with and without server vacations, with compound Poisson input, and with generally distributed service and vacation periods. The analysis of the models is essentially based on fluctuation techniques for two-dimensional marked counting processes newly developed by the author. The results enable us to arrive at stationary distributions for the embedded and continuous time parameter queueing processes in closed analytic forms, enhancing the well-known Kendall formulas and their modifications.

  11. From chloroquine to artemether-lumefantrine: the process of drug policy change in Zambia

    Directory of Open Access Journals (Sweden)

    Snow Robert W

    2008-01-01

    Full Text Available Abstract Background Following the recognition that morbidity and mortality due to malaria had dramatically increased in the last three decades, in 2002 the government of Zambia reviewed its efforts to prevent and treat malaria. Convincing evidence of the failing efficacy of chloroquine resulted in the initiation of a process that eventually led to the development and implementation of a new national drug policy based on artemisinin-based combination therapy (ACT. Methods All published and unpublished documented evidence dealing with the antimalarial drug policy change was reviewed. These data were supplemented by the authors' observations of the policy change process. The information has been structured to capture the timing of events, the challenges encountered, and the resolutions reached in order to achieve implementation of the new treatment policy. Results A decision was made to change national drug policy to artemether-lumefantrine (AL in the first quarter of 2002, with a formal announcement made in October 2002. During this period, efforts were undertaken to identify funding for the procurement of AL and to develop new malaria treatment guidelines, training materials, and plans for implementation of the policy. In order to avoid a delay in implementation, the policy change decision required a formal adoption within existing legislation. Starting with donated drug, a phased deployment of AL began in January 2003 with initial use in seven districts followed by scaling up to 28 districts in the second half of 2003 and then to all 72 districts countrywide in early 2004. Conclusion Drug policy changes are not without difficulties and demand a sustained international financing strategy for them to succeed. The Zambian experience demonstrates the need for a harmonized national consensus among many stakeholders and a political commitment to ensure that new policies are translated into practice quickly. To guarantee effective policies requires

  12. Influence in the Policy Making Process: the Rise of Economics at the Expense of Geology

    Science.gov (United States)

    McCurdy, K. M.

    2007-12-01

    Scientific influence in resource policy making reached a zenith in the early 1970s during the legislative monopoly in the United States Congress that produced command and control regulatory protection policies. This congressional consensus began in 1879 with legislation producing the U.S. Geological Survey. Other scientific agencies followed. The Congresses of the first half of the 20th century merely strengthened the influence of science in policy outcomes that was present in the earliest congressional debates. What then happened at the turn of the 21st century when representatives in the administration frequently dismissed sound science in their policy deliberations? Policy monopolies arise from agreement in principle, and alternately decline as rival ideas gain hold in policy space. The science policy monopoly began to face competition from economics when cost benefit analysis was introduced into political parlance in 1936, again in the 1950s as a successful blocking tactic by the minority in opposition to western dams, and in 1961 when systems analysis was introduced to the Department of Defense under Robert McNamara. As businessmen replaced farmers as the modal profession of legislators, the language of politics increasingly contained economic terms and concepts. A ternary diagram and a budget simplex have the same shape, but have different theoretical meanings and imply different processes. Policy consensus is not dissimilar to a mineral phase diagram, with boundary conditions marked by election magnitudes and majority parties. The 1980 elections brought economic principles into all aspects of government decision-making, with a particular long-term interest in reducing the size and scope of government. Since then the shift in policy jargon from science to economics has been incremental. With the 1994 Republican legislative majority, scientists, their programs, and the funds required to maintain data collection projects became targets. The Conservative

  13. Enhancing Wikipedia Editing with WAI-ARIA

    Science.gov (United States)

    Senette, Caterina; Buzzi, Maria Claudia; Buzzi, Marina; Leporini, Barbara

    Nowadays Web 2.0 applications allow anyone to create, share and edit on-line content, but accessibility and usability issues still exist. For instance, Wikipedia presents many difficulties for blind users, especially when they want to write or edit articles. In a previous stage of our study we proposed and discussed how to apply the W3C ARIA suite to simplify the Wikipedia editing page when interacting via screen reader. In this paper we present the results of a user test involving totally blind end-users as they interacted with both the original and the modified Wikipedia editing pages. Specifically, the purpose of the test was to compare the editing and formatting process for original and ARIA-implemented Wikipedia user interfaces, and to evaluate the improvements.

  14. Ratification of the Kyoto Protocol: a citizen's guide to the Canadian climate change policy process

    International Nuclear Information System (INIS)

    Macdonald, D.; Bjorn, A.; Duminuco, S.

    2002-01-01

    Canada is faced with the important decision of whether it should ratify the Kyoto Protocol. A reference for stakeholders and non-expert interested parties, this document is a guide into the Canadian Climate Change Policy Process. An understanding of climate science is required for climate policy, as is a knowledge of policy options available to overcome the challenges posed by climate change. The situation is further complicated by international and federal-provincial negotiations over the measures that should be implemented, if any. Climate policy affects all aspects of our lives, especially how we produce and use energy. An overview of climate science is provided in the first section, and the relationship between climate and rising temperatures due to greenhouse gas emissions is established. The sources of greenhouse gases in Canada are identified, with a closer look at the current trends. The Kyoto Protocol, if ratified, calls for Canada to reduce its emissions of greenhouse gases to six per cent below 1990 levels. It is noted that to date, Canada's emissions have risen 19.7 per cent above 1990 levels. The process underlying the international negotiations associated with the Kyoto Protocol, and especially Canada's role in it, are discussed. Flexibility mechanisms are strongly supported by Canada, such as credits for sinks, international carbon trading and credits for Clean Energy Exports. By approving such measures, the integrity of the Protocol would be considerably weakened. The domestic policy-making environment is examined, presenting key federal, provincial business and environmental players. In addition, the policy process in Canada is described, as well as the decisions made up to September 2002. Bibliographic and contact information is added in the last section of the document. 89 refs., 7 tabs., 7 figs

  15. [The role of the state and society relationship in the foreign policy making process : arvustus] / Hiski Haukkala

    Index Scriptorium Estoniae

    Haukkala, Hiski

    2013-01-01

    Arvustus: Maria Groeneveld. The role of the state and society relationship in the foreign policy making process. Tartu : Tartu University Press, 2012. ( Dissertationes rerum politicarum Universitatis Tartuensis ; 7)

  16. Geometric-Process-Based Battery Management Optimizing Policy for the Electric Bus

    OpenAIRE

    Li, Yan; Wang, Jin-kuan; Han, Peng; Han, Ying-hua

    2015-01-01

    With the rapid development of the electric vehicle industry and promotive policies worldwide, the electric bus (E-bus) has been adopted in many major cities around the world. One of the most important factors that restrain the widespread application of the E-bus is the high operating cost due to the deficient battery management. This paper proposes a geometric-process-based (GP-based) battery management optimizing policy which aims to minimize the average cost of the operation on the premise ...

  17. Policy Iteration for Continuous-Time Average Reward Markov Decision Processes in Polish Spaces

    Directory of Open Access Journals (Sweden)

    Quanxin Zhu

    2009-01-01

    Full Text Available We study the policy iteration algorithm (PIA for continuous-time jump Markov decision processes in general state and action spaces. The corresponding transition rates are allowed to be unbounded, and the reward rates may have neither upper nor lower bounds. The criterion that we are concerned with is expected average reward. We propose a set of conditions under which we first establish the average reward optimality equation and present the PIA. Then under two slightly different sets of conditions we show that the PIA yields the optimal (maximum reward, an average optimal stationary policy, and a solution to the average reward optimality equation.

  18. Introducing payment for performance in the health sector of Tanzania- the policy process.

    Science.gov (United States)

    Chimhutu, Victor; Tjomsland, Marit; Songstad, Nils Gunnar; Mrisho, Mwifadhi; Moland, Karen Marie

    2015-09-02

    Prompted by the need to achieve progress in health outcomes, payment for performance (P4P) schemes are becoming popular policy options in the health systems in many low income countries. This paper describes the policy process behind the introduction of a payment for performance scheme in the health sector of Tanzania illuminating in particular the interests of and roles played by the Government of Norway, the Government of Tanzania and the other development partners. The study employed a qualitative research design using in-depth interviews (IDIs), observations and document reviews. Thirteen IDIs with key-informants representing the views of ten donor agencies and government departments influential in the process of introducing the P4P scheme in Tanzania were conducted in Dar es Salaam, Tanzania and Oslo, Norway. Data was collected on the main trends and thematic priorities in development aid policy, countries and actors perceived to be proponents and opponents to the P4P scheme, and P4P agenda setting in Tanzania. The initial introduction of P4P in the health sector of Tanzania was controversial. The actors involved including the bilateral donors in the Health Basket Fund, the World Bank, the Tanzanian Government and high level politicians outside the Health Basket Fund fought for their values and interests and formed alliances that shifted in the course of the process. The process was characterized by high political pressure, conflicts, changing alliances, and, as it evolved, consensus building. The P4P policy process was highly political with external actors playing a significant role in influencing the agenda in Tanzania, leaving less space for the Government of Tanzania to provide leadership in the process. Norway in particular, took a leading role in setting the agenda. The process of introducing P4P became long and frustrating causing mistrust among partners in the Health Basket Fund.

  19. ILC-BR (2015), Active Ageing : A Policy Framework in Response to the Longevity Revolution, 1st edition, International Longevity Centre Brazil, Rio de Janeiro, Brazil

    OpenAIRE

    Bárrios, Maria João

    2016-01-01

    O documento publicado pela OMS em 2002 : Active Ageing. A Policy Framework (WHO, 2002) tem sido destacado como um marco nas políticas de saúde e envelhecimento, inspirando o desenvolvimento de programas nacionais e locais baseados no conceito de “envelhecimento ativo”. É este conceito que sustenta medidas políticas adotadas em vários países e regiões como o projeto “As Cidades Amigas das Pessoas Idosas” (WHO, 2007), que reforça estratégias como o “Movimento Cidades Saudáveis” (WHO, 2014) e qu...

  20. Substantive Editing as a Form of Plagiarism among Postgraduate Students in Australia

    Science.gov (United States)

    Lines, Lisa

    2016-01-01

    In university plagiarism policies, and in the research into plagiarism, one form of collusion remains virtually unacknowledged: substantive editing performed by editors. While almost all Australian universities allow postgraduate students to have their thesis professionally edited, "substantive" editing is prohibited. This article…

  1. Does Money Matter in Education? Second Edition

    Science.gov (United States)

    Baker, Bruce D.

    2016-01-01

    This second edition policy brief revisits the long and storied literature on whether money matters in providing a quality education. It includes research released since the original brief in 2012 and covers a handful of additional topics. Increasingly, political rhetoric adheres to the unfounded certainty that money does not make a difference in…

  2. School Law: Cases and Concepts. Seventh Edition.

    Science.gov (United States)

    LaMorte, Michael W.

    This book examines the sizable body of school law that outlines legally defensible decisions. A substantial part of it contains edited, reported, and verbatim decisions. Historical perspective is provided, as well as specific case and statutory law. Chapter 1 discusses sources of law for educators, state school board policies, attorneys-general…

  3. Fostering a Durable Relationship between a Radioactive Waste Management Facility and its Host Community. Adding Value through Design and Process. 2015 Edition

    International Nuclear Information System (INIS)

    2015-01-01

    In the field of long-term radioactive waste management, repository projects last from decades to centuries. Such projects will inevitably have an effect on the host community from the planning stage to the end of construction and beyond. The key to a long-lasting and positive relationship between a facility and its host community is ensuring that solutions are reached together throughout the entire process. The sustainability of radioactive waste management solutions can potentially be achieved through design and implementation of a facility that provides added cultural and amenity value, as well as economic opportunities, to the local community. This edition of Fostering a Durable Relationship between a Waste Management Facility and its Host Community: Adding Value through Design and Process highlights new innovations in siting processes and in facility design - functional, cultural and physical - from different countries, which could be of added value to host communities and their sites in the short to long term. These new features are examined from the perspective of sustainability, with a focus on increasing the likelihood that people will both understand the facility and its functions, and remember over very long timescales what is located at the site. This 2015 update by the NEA Forum on Stakeholder Confidence will be beneficial in designing paths forward for local or regional communities, as well as for national radioactive waste management programmes. Section 2 of this report summarises the value of developing a sustainable relationship between a community and a radioactive waste management facility through added cultural and amenity value. In Section 3, the report identifies design considerations - functional, cultural and physical - that may help facilities to fit into the community in a sustainable manner. Each design feature is illustrated with examples. Section 4 discusses the benefits that may be gained from the very process of planning radioactive

  4. The commercialization of genome-editing technologies.

    Science.gov (United States)

    Brinegar, Katelyn; K Yetisen, Ali; Choi, Sun; Vallillo, Emily; Ruiz-Esparza, Guillermo U; Prabhakar, Anand M; Khademhosseini, Ali; Yun, Seok-Hyun

    2017-11-01

    The emergence of new gene-editing technologies is profoundly transforming human therapeutics, agriculture, and industrial biotechnology. Advances in clustered regularly interspaced short palindromic repeats (CRISPR) have created a fertile environment for mass-scale manufacturing of cost-effective products ranging from basic research to translational medicine. In our analyses, we evaluated the patent landscape of gene-editing technologies and found that in comparison to earlier gene-editing techniques, CRISPR has gained significant traction and this has established dominance. Although most of the gene-editing technologies originated from the industry, CRISPR has been pioneered by academic research institutions. The spinout of CRISPR biotechnology companies from academic institutions demonstrates a shift in entrepreneurship strategies that were previously led by the industry. These academic institutions, and their subsequent companies, are competing to generate comprehensive intellectual property portfolios to rapidly commercialize CRISPR products. Our analysis shows that the emergence of CRISPR has resulted in a fivefold increase in genome-editing bioenterprise investment over the last year. This entrepreneurial movement has spurred a global biotechnology revolution in the realization of novel gene-editing technologies. This global shift in bioenterprise will continue to grow as the demand for personalized medicine, genetically modified crops and environmentally sustainable biofuels increases. However, the monopolization of intellectual property, negative public perception of genetic engineering and ambiguous regulatory policies may limit the growth of these market segments.

  5. Role of Evidence in Maternal Health Policy Processes in Vietnam, India and China: Findings from the HEPVIC Project

    Science.gov (United States)

    Mirzoev, Tolib; Green, Andrew; Gerein, Nancy; Pearson, Stephen; Bird, Philippa; Ha, Bui Thi Thu; Ramani, Karaikurichi; Qian, Xu; Yang, Xiaoguang; Mukhopadhyay, Maitrayee; Soors, Werner

    2013-01-01

    This paper explores the role of evidence in maternal health policy processes in Vietnam, India and China. Both formal and informal types of evidence were used; and differences were found between the stages of policy processes. Evidence used mostly covered easily quantifiable issues and clearly identifiable technical solutions. Different policy…

  6. WHO policy development processes for a new vaccine: case study of malaria vaccines.

    Science.gov (United States)

    Milstien, Julie; Cárdenas, Vicky; Cheyne, James; Brooks, Alan

    2010-06-24

    Recommendations from the World Health Organization (WHO) are crucial to inform developing country decisions to use, or not, a new intervention. This article analysed the WHO policy development process to predict its course for a malaria vaccine. The decision-making processes for one malaria intervention and four vaccines were classified through (1) consultations with staff and expert advisors to WHO's Global Malaria Programme (GMP) and Immunization, Vaccines and Biologicals Department (IVB); (2) analysis of the procedures and recommendations of the major policy-making bodies of these groups; (3) interviews with staff of partnerships working toward new vaccine availability; and (4) review and analyses of evidence informing key policy decisions. WHO policy formulation related to use of intermittent preventive treatment in infancy (IPTi) and the following vaccine interventions: Haemophilus influenzae type b conjugate vaccine (Hib), pneumococcal conjugate vaccine (PCV), rotavirus vaccine (RV), and human papillomavirus vaccine (HPV), five interventions which had relatively recently been through systematic WHO policy development processes as currently constituted, was analysed. Required information was categorized in three areas defined by a recent WHO publication on development of guidelines: safety and efficacy in relevant populations, implications for costs and population health, and localization of data to specific epidemiological situations. Data needs for a malaria vaccine include safety; the demonstration of efficacy in a range of epidemiological settings in the context of other malaria prevention interventions; and information on potential rebound in which disease increases subsequent to the intervention. In addition, a malaria vaccine would require attention to additional factors, such as costs and cost-effectiveness, supply and demand, impact of use on other interventions, and distribution issues. Although policy issues may be more complex for future vaccines

  7. The process of institutionalising the EU’s anti-terrorist policy

    Directory of Open Access Journals (Sweden)

    Javier Argomaniz

    2010-09-01

    Full Text Available This article applies the perspective of historical institutionalism to the empirical analysis of the motors and characteristics of the institutionalisation process of the European Union’s anti-terrorist policies. Based on a theoretical model developed by Stone Sweet, Sandholtz and Fligstein, this contribution critically analyses the impact of external crises in the form of a series of terrorist attacks on the emergence of antiterrorism as an sphere of European governance. The article also examines political developments and key institutions, studies the role of policy entrepreneurs during this period and compares the importance of “revolutionary” and “evolutionist” perspectives to our understanding of the process of institutional change in this field.

  8. Spatial misfits in a multi-level renewable energy policy implementation process on the Small Island State of Malta

    International Nuclear Information System (INIS)

    Kotzebue, Julia R.; Bressers, Hans Th.A.; Yousif, Charles

    2010-01-01

    One of the priorities of energy policies of the European Union (EU) is to generate 20% of EU's total energy consumption from renewable energy (RE) sources by 2020. The EU policy framework mainly emphasizes economical and technical aspects of RE sources, and promotes large scale projects. However the local implementation of RE EU policies can lead to spatial misfits if the policy implementation neglects the peculiarities of the place. It is important to understand the misfits and relationship between the EU RE policies and the local implementation process, as misfits can affect the policy implementation process and subsequently policy outcomes can be different from those intended, leading to inapt or inapplicable measures. This article presents findings of a qualitative in-depth study of Malta's RE policy implementation. The paper shows that planning of central large-scale RE projects in Malta provokes land and marine use conflicts and can cause difficulties in implementation. The concerned key actors implement the policies according to their motivation, perception, and capacity, and the context in which they are embedded. Hence, both the EU RE policy framework and the national interaction process influence the implementation process, which can lead to spatial mismatches.

  9. Embracing the Complexity of Policy Processes in Sanitation: Insights from India

    OpenAIRE

    Hueso, Andrés; Boni Aristizábal, Alejandra; Fernández-Baldor, Álvaro

    2018-01-01

    [EN] Different stakeholders tried participatory approaches to boost progress in rural sanitation in India. The policy processes around these experiences, despite shaping their outcomes, remain a knowledge gap this paper addresses. Evidence show that the interests of the actors involved resulted in the national campaign being construction-focused. Therefore, participatory approaches could only be successfully introduced through networks with political champions at their centre. Moreover, polit...

  10. Clashing frames: human rights and foreign policy in the Brazilian re-democratization process

    Directory of Open Access Journals (Sweden)

    João Henrique Roriz

    2017-11-01

    Full Text Available Abstract This article deals with the use of rights in the Brazilian foreign policy in the late 1970s. Two main arguments are advanced: there was a novel understanding of rights that clashed with the traditional statist one, and the Brazilian strategies were less a complete rebuttal of rights language and more a reading of rights as a possible threat to the Abertura process.

  11. Sub-national entities’ participation in Brazil’s foreign policy and in regional integration processes

    Directory of Open Access Journals (Sweden)

    Deisy Ventura

    2012-09-01

    Full Text Available This article focuses on how sub-national entities’ gradual participation in Brazilian foreign policy has come about, with reference to a decentralised scenario of the decision-making process in Itamaraty, where the ministries and presidential organs have a voice on many strategic themes, mainly concerning development. The article examines the insertion of sub-national entities into the decision-making process in the Southern Common Market (Mercosur, and concludes that in spite of the incipient participation, relevant contributions to the process of regional integration have arisen. Regarding the hypothesis that the participation of the federative entities in the decision-making process generates local and regional development, we argue that this is an alternative to increasing state efficiency. In conclusion, and despite the incipient institutionalisation that does not guarantee their vote in the decision-making process, at least their voice is heard.

  12. Global Environmental Problems: Implications for U.S. Policy. Tenth Edition. Teacher Resource Book [and Student Text]. Public Policy Debate in the Classroom. Choices for the 21st Century.

    Science.gov (United States)

    Fox, Sarah Cleveland

    Scientists have increasingly focused attention on far-reaching environmental threats, such as climate change, ozone depletion, and deforestation, that transcend national boundaries. A new concept, global environmental problems, has entered the public arena, particularly in the area of foreign policy and economic matters. This unit explores the…

  13. ‘Rowing against the current’: the policy process and effects of removing user fees for caesarean sections in Benin

    Science.gov (United States)

    Cresswell, Jenny A; Makoutodé, Patrick; De Brouwere, Vincent; Witter, Sophie; Filippi, Veronique; Kanhonou, Lydie G; Goufodji, Sourou B; Lange, Isabelle L; Lawin, Lionel; Affo, Fabien; Marchal, Bruno

    2018-01-01

    Background In 2009, the Benin government introduced a user fee exemption policy for caesarean sections. We analyse this policy with regard to how the existing ideas and institutions related to user fees influenced key steps of the policy cycle and draw lessons that could inform the policy dialogue for universal health coverage in the West African region. Methods Following the policy stages model, we analyse the agenda setting, policy formulation and legitimation phase, and assess the implementation fidelity and policy results. We adopted an embedded case study design, using quantitative and qualitative data collected with 13 tools at the national level and in seven hospitals implementing the policy. Results We found that the initial political goal of the policy was not to reduce maternal mortality but to eliminate the detention in hospitals of mothers and newborns who cannot pay the user fees by exempting a comprehensive package of maternal health services. We found that the policy development process suffered from inadequate uptake of evidence and that the policy content and process were not completely in harmony with political and public health goals. The initial policy intention clashed with the neoliberal orientation of the political system, the fee recovery principles institutionalised since the Bamako Initiative and the prevailing ideas in favour of user fees. The policymakers did not take these entrenched factors into account. The resulting tension contributed to a benefit package covering only caesarean sections and to the variable implementation and effectiveness of the policy. Conclusion The influence of organisational culture in the decision-making processes in the health sector is often ignored but must be considered in the design and implementation of any policy aimed at achieving universal health coverage in West African countries. PMID:29564156

  14. Multiplex editing system

    DEFF Research Database (Denmark)

    2015-01-01

    The present invention relates to a multiplex editing system. The system allows multiple editing of nucleic acid sequences such as genomic sequences, such as knockins of genes of interest in a genome, knockouts of genomic sequences and/or allele replacement. Also provided herein are a method...

  15. A Community Health Clinic Breastfeeding-Friendly Pilot: What Can We Learn about the Policy Process?

    Science.gov (United States)

    Johnson, Donna B; Lamson, Erica; Schwartz, Rachel; Goldhammer, Camie; Ellings, Amy

    2015-11-01

    Implementing evidence-based practices and policies for breastfeeding support in community clinics is a promising, but challenging, approach to reducing disparities in breastfeeding rates. This study aimed to apply a policy process research framework to increase knowledge of factors that facilitate adoption and implementation of breastfeeding policy changes. In 2013, Washington State piloted a process to encourage 8 clinics to adopt and implement steps to become breastfeeding friendly. Evaluation data were collected through interviews, project reports, training evaluations, and pre- and post-self-assessments of achievement of the steps. In 6 months, clinics increased the breastfeeding-friendly steps that they were implementing from a median (interquartile range) of 1.5 (0-3) to 6 (5-7). Improvements were most likely in the steps that required the fewest resources and administrative changes. Barriers to implementation included misperceptions about breastfeeding and breastfeeding support; lack of administrative "buy-in"; need for organizational changes to accommodate actions like monitoring breastfeeding rates and allowing providers training time; and the social-political climate of the clinic. Several factors, including actions taken by public health practitioners, enhanced the change process. These included fostering supportive relationships, targeting technical assistance, and providing resources for planning and training. This pilot project demonstrates that it is possible to make changes in breastfeeding support practices and policies in community clinics. Recommendations to enhance future work include framing and marketing breastfeeding support in ways that resonate with clinic decision makers and enhancing training, resources, and advocacy to build capacity for internal and external systems changes to support breastfeeding best practices. © The Author(s) 2015.

  16. [Processes in the construction of the Brazilian National Health Promotion Policy].

    Science.gov (United States)

    Ferreira Neto, João Leite; Kind, Luciana; Resende, Maria Carolina Costa; Colen, Natália Silva

    2013-10-01

    We investigated the processes involved in the construction of the Brazilian National Health Promotion Policy (PNPS) through the analysis of three documents produced by the Ministry of Health from 2002 to 2005 and the final text of the National Health Promotion Policy, approved in 2006. We interviewed five subjects who participated in drafting the PNPS, three of whom were Ministry of Health administrators, plus two researchers. The documents were explored with discourse analysis. The article contributes to the debate on the development of the PNPS. Health promotion showed various points of disagreement, which led to the delay in the document's final approval. International induction via funding proved to be a crucial element for defining the final wording of the PNPS, reestablishing the emphasis (subject to criticism) on lifestyle changes in its "Actions". The article highlights the negotiated consensus that led to the creation of the PNPS Management Committee, with participation by various sub-sectors, an innovative structure within the Ministry of Health.

  17. Serbian migration policy concerning irregular migration and asylum in the context of the EU integration process

    Directory of Open Access Journals (Sweden)

    Marta Stojić-Mitrović

    2016-02-01

    Full Text Available In this paper I would like to present Serbian migration policy concerning irregular migration and asylum in the context of the attempts of the Serbian state to become a member of the European Union. I would describe the history of the asylum system prior and after the implementation of the independent asylum system in Serbia in 2008. My presentation of the Serbian migration policy would be channelled by the analysis of some particular political issues, such as the externalization of the EU borders’ control, as well as some relevant elements of the European integration process, like visa liberalization. The second, more culturally specific dimension of the issue would be accessed through the demonstration of both legislative and public conceptualizations of the irregular migrants, asylum seekers and refugees in Serbia.

  18. CULTURAL PHENOMENA AND PROCESSES IN CONTEMPORARY SOCIETY – DETERMINANTS OF CULTURAL POLICIES

    Directory of Open Access Journals (Sweden)

    ANDREEA MIHAELA NITA

    2012-05-01

    Full Text Available Cultural phenomena and processes in the contemporary society, influenced by the social development models and by the fact that the constitutive elements of the culture have become the decisive factors of social change, are the determinants of the cultural policies. They are centered on the active process of cultural globalization that emphasizes besides the assimilation of the European principles, also the preservation of the cultural dialog without identity loss. Contemporary culture cannot be appreciated unless we know the main processes and phenomena that lately have generated impressive changes in the area of technology and means of communication. Due to these transformations we witness a change of the cultural paradigms, a mutation of values.

  19. From Capitol Hill to Dupont Circle and Beyond: The Influence of Policy Actors in the Federal Higher Education Rulemaking Process

    Science.gov (United States)

    Natow, Rebecca S.

    2015-01-01

    The federal higher education rulemaking process develops policies that can profoundly affect college students, higher education institutions, and other actors in the higher education policy community. But little has been researched about the influence that different types of actors have on higher education rulemaking. By analyzing interviews with…

  20. Genome editing systems in novel therapies.

    Science.gov (United States)

    Jang, Yoon-Young; Cai, Liuhong; Ye, Zhaohui

    2016-01-01

    Genome editing is the process in which DNA sequences at precise genomic locations are modified. In the past three decades, genome editing by homologous recombination has been successfully performed in mouse for generating genetic models. The low efficiency of this process in human cells, however, had prevented its clinical application until the recent advancements in designer endonuclease technologies. The significantly improved genome editing efficiencies aided by ZFN, TALEN, and CRISPR systems provide unprecedented opportunities not only for biomedical research, but also for developing novel therapies. Applications based on these genome editing tools to disrupt deleterious genes, correct genetic mutations, deliver functional transgenes more effectively or even modify the epigenetic landscape are being actively investigated for gene and cell therapy purposes. Encouraging results have been obtained in limited clinical trials in the past two years. While most of the applications are still in proof-of-principle or preclinical development stages, it is anticipated that the coming years will see increasing clinical success in novel therapies based on the modern genome editing technologies. It should be noted that critical issues still remain before the technologies can be translated into more reliable therapies. These key issues include off-target evaluation, establishing appropriate preclinical models and improving the currently low efficiency of homology-based precise gene replacement. In this review we discuss the preclinical and clinical studies aiming at translating the genome editing technologies as well as the issues that are important for more successful translation.

  1. MRB3010 is a core component of the MRB1 complex that facilitates an early step of the kinetoplastid RNA editing process

    Czech Academy of Sciences Publication Activity Database

    Ammerman, M. L.; Hashimi, Hassan; Novotná, Lucie; Číčová, Zdeňka; Mcevoy, S. M.; Lukeš, Julius; Read, L. K.

    2011-01-01

    Roč. 17, č. 5 (2011), 865-877 ISSN 1355-8382 R&D Projects: GA ČR GA204/09/1667; GA MŠk 2B06129; GA MŠk LC07032 Institutional research plan: CEZ:AV0Z60220518 Keywords : RNA editing * trypanosome * MRB1 complex * mitochondria * kinetoplast Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 5.095, year: 2011

  2. An Analysis of the Extent of Social Inclusion and Equity Consideration in Malawi's National HIV and AIDS Policy Review Process.

    Science.gov (United States)

    Chinyama, Mathews Junior; MacLachlan, Malcolm; McVeigh, Joanne; Huss, Tessy; Gawamadzi, Sylvester

    2017-07-29

    Equity and social inclusion for vulnerable groups in policy development processes and resulting documents remain a challenge globally. Most often, the marginalization of vulnerable groups is overlooked in both the planning and practice of health service delivery. Such marginalization may occur because authorities deem the targeting of those who already have better access to healthcare a cheaper and easier way to achieve short-term health gains. The Government of Malawi wishes to achieve an equitable and inclusive HIV and AIDS Policy. The aim of this study is to assess the extent to which the Malawi Policy review process addressed regional and international health priorities of equity and social inclusion for vulnerable groups in the policy content and policy revision process. This research design comprised two phases. First, the content of the Malawi HIV and AIDS Policy was assessed using EquiFrame regarding its coverage of 21 Core Concepts of human rights and inclusion of 12 Vulnerable Groups. Second, the engagement of vulnerable groups in the policy process was assessed using the EquIPP matrix. For the latter, 10 interviews were conducted with a purposive sample of representatives of public sector, civil society organizations and development partners who participated in the policy revision process. Data was also collected from documented information of the policy processes. Our analyses indicated that the Malawi HIV and AIDS Policy had a relatively high coverage of Core Concepts of human rights and Vulnerable Groups; although with some notable omissions. The analyses also found that reasonable steps were taken to engage and promote participation of vulnerable groups in the planning, development, implementation, monitoring and evaluation processes of the HIV and AIDS Policy, although again, with some notable exceptions. This is the first study to use both EquiFrame and EquIPP as complimentary tools to assess the content and process of policy. While the findings

  3. A national public health programme on gambling policy development in New Zealand: insights from a process evaluation.

    Science.gov (United States)

    Kolandai-Matchett, Komathi; Landon, Jason; Bellringer, Maria; Abbott, Max

    2018-03-06

    In New Zealand, a public health programme on gambling policy development is part of a national gambling harm reduction and prevention strategy mandated by the Gambling Act 2003. Funded by the Ministry of Health, the programme directs workplace/organisational gambling policies, non-gambling fundraising policies, and local council policies on electronic gaming machines (EGMs). We carried out a process evaluation of this programme to identify practical information (e.g. advocacy approaches; challenges and ameliorating strategies) that can be used by programme planners and implementers to reinforce programme effectiveness and serve to guide similar policy-focused public health initiatives elsewhere. Evaluation criteria, based on the programme's official service specifications, guided our evaluation questions, analysis and reporting. To identify informative aspects of programme delivery, we thematically analysed over 100 six-monthly implementer progress reports (representing 3 years of programme delivery) and transcript of a focus group with public health staff. Identified output-related themes included purposeful awareness raising to build understanding about gambling harms and the need for harm-reduction policies and stakeholder relationship development. Outcome-related themes included enhanced community awareness about gambling harms, community involvement in policy development, some workplace/organisational policy development, and some influences on council EGM policies. Non-gambling fundraising policy development was not common. The programme offers an unprecedented gambling harm reduction approach. Although complex (due to its three distinct policy focus areas targeting different sectors) and challenging (due to the extensive time and resources needed to develop relationships and overcome counteractive views), the programme resulted in some policy development. Encouraging workplace/organisational policy development requires increased awareness of costs to

  4. The European Union Cohesion Policy in Romania - Strategic Approach to the Implementation Process

    Directory of Open Access Journals (Sweden)

    LAZAR Szilard

    2012-06-01

    Full Text Available Achieving economic, social and territorial cohesion by reducing existing disparities between regions through investing in infrastructure, human resources and diversification of regional economies remains a major goal for the EU Member States. The achievement of this goal would not be possible without the development and implementation of regional policy strategic instruments at national and EU level. This study presents the role, the essential elements, and objectives of instruments such as the Community Strategic Guidelines on Cohesion, the National Strategic Reference Framework, and the Romanian Operational Programmes for the programming period 2007-2013. Since the success of the cohesion policy is tied to its implementation, we also present the management and control system applicable for the operational programmes. The final part of the study deals with issues concerning the payment rate of Structural Funds in Romania, with a focus on the main challenges of the implementation process. An important task for the Romanian government is to remove the obstacles that brake the effective implementation of the Cohesion policy and the absorption of Structural and Cohesion Funds.

  5. Processes and challenges of the interaction betweeen research and policy from the perspective of researchers.

    Science.gov (United States)

    Angulo-Tuesta, Antonia; Santos, Leonor Maria Pacheco; Iturri, José Antonio

    2018-01-01

    Evidence-informed policies can produce social and economic impacts and equity and health benefits. Interaction between researchers in politics depends on the interests of social stakeholders and favorable political environments. This paper seeks to understand the meanings and researchers' perspectives of interaction processes between scientists and decision-makers that would influence the research impact on the health policy. This is a qualitative content analysis study conducted in 2014 to identify the core meanings and relationships between research and politics. The paper builds on the RAPID program approach of the Overseas Development Institute. Fourteen researchers who conducted maternal and neonatal morbidity and mortality studies sponsored by the Health Ministry were interviewed. Researchers focused on the production of knowledge, strengthening of research capacities and dissemination of results. On some occasions, researchers also participated in the definition of clinical care policies and performance of health services. They pointed to barriers to interact and produce an impact on politics due to tensions in the political, economic and social context, as well as to institutional and organizational changes in the health sector and to the academic evaluation system.

  6. One small edit for humans, one giant edit for humankind? Points and questions to consider for a responsible way forward for gene editing in humans.

    Science.gov (United States)

    Howard, Heidi C; van El, Carla G; Forzano, Francesca; Radojkovic, Dragica; Rial-Sebbag, Emmanuelle; de Wert, Guido; Borry, Pascal; Cornel, Martina C

    2018-01-01

    Gene editing, which allows for specific location(s) in the genome to be targeted and altered by deleting, adding or substituting nucleotides, is currently the subject of important academic and policy discussions. With the advent of efficient tools, such as CRISPR-Cas9, the plausibility of using gene editing safely in humans for either somatic or germ line gene editing is being considered seriously. Beyond safety issues, somatic gene editing in humans does raise ethical, legal and social issues (ELSI), however, it is suggested to be less challenging to existing ethical and legal frameworks; indeed somatic gene editing is already applied in (pre-) clinical trials. In contrast, the notion of altering the germ line or embryo such that alterations could be heritable in humans raises a large number of ELSI; it is currently debated whether it should even be allowed in the context of basic research. Even greater ELSI debates address the potential use of germ line or embryo gene editing for clinical purposes, which, at the moment is not being conducted and is prohibited in several jurisdictions. In the context of these ongoing debates surrounding gene editing, we present herein guidance to further discussion and investigation by highlighting three crucial areas that merit the most attention, time and resources at this stage in the responsible development and use of gene editing technologies: (1) conducting careful scientific research and disseminating results to build a solid evidence base; (2) conducting ethical, legal and social issues research; and (3) conducting meaningful stakeholder engagement, education and dialogue.

  7. DEMOGRAPHIC IMPERATIVES OF MODERNIZATION PROCESSES IN EDUCATIONAL POLICY (FOR EXAMPLE REGIONS OF INNER ASIA

    Directory of Open Access Journals (Sweden)

    Tatiana Innokentievna Garmaeva

    2017-02-01

    Methodological basis of the research are the historical, sociological methods, and also systematic and structural-functional analysis. The results of the research will help to determine the demographic processes in the cross-border regions of Inner Asia, in particular in the Republic of Buryatia (Russia, Autonomous Region of Inner Mongolia (China, Mongolia; the possibility of the higher education system’s development in the designated regions. The obtained results can be used in the work of public authorities involved in the development of public policy in the field of education, in reading of the lecture course, special seminars on pedagogy and history of education for the students and specialists of humanities.

  8. Towards a Nordic child care policy – the political processes and agendas

    DEFF Research Database (Denmark)

    Rostgaard, Tine; Eydal, Gudny

    2012-01-01

    This chapter will address the question of why childcare policies have been shaped in the way that it has. In other words, the chapter examines the underlying political processes and the agendas of the various political parties. In the literature about the driving forces of welfare state development......, two types of approaches have dominated the theoretical debate: functionalism, stressing the importance of structures and whole systems, and conflict theories, stressing institutions and actors (Borchorst & Siim 2009; Esping-Andersen 1991). This chapter will adopt a conflict-theory perspective....

  9. Participation, public policy-making, and legitimacy in the EU Voluntary Partnership Agreement process

    DEFF Research Database (Denmark)

    Wodschow, Astrid; Nathan, Iben; Cerutti, Paolo

    2016-01-01

    This paper discusses how participatory policy-making processes such as the Voluntary Partnership Agreement (VPA) negotiations are and should be organised to foster political legitimacy and support. The VPAs are bilateral agreements between the European Union (EU) and timber producing countries....... VPAs constitute a cornerstone in EU's Forest Law Enforcement, Governance and Trade (FLEGT) programme, the most important tool for the EU to address illegal logging problems. The EU requires that national VPA negotiations include participation by the relevant stakeholders. Based on primary data, we...

  10. Political economy of renewable energy policy in Germany. A consideration of the policy making process in the electricity market under the influence of interest groups

    International Nuclear Information System (INIS)

    Mueller, Tom

    2015-01-01

    In the research, it is argued that the targeted promotion of renewables leads to a change in the technological path dependency on the electricity market or led. The historically market depending portfolio of products in the conventional power industry will be replaced by an increasingly strong dependence on the product portfolio of Renewable Energy Sector according to this argumentation. The present work is devoted to the political explanation of the change and transition process in the electricity market. The process of policy formation in this market (especially support policies for renewable energies) will be discussed. It is examined from a public choice perspective, which political actors and instances in the past were responsible for the development and maintenance of individual policy elements. In particular, in this analysis the different private sector stakeholders in the electricity market move to center of attention. [de

  11. CRISPR Genome Editing

    Science.gov (United States)

    A research article about a technique for gene editing known as CRISPR-Cas9. The technique has made it much easier and faster for cancer researchers to study mutations and test new therapeutic targets.

  12. The genome editing revolution

    DEFF Research Database (Denmark)

    Stella, Stefano; Montoya, Guillermo

    2016-01-01

    -Cas system has become the main tool for genome editing in many laboratories. Currently the targeted genome editing technology has been used in many fields and may be a possible approach for human gene therapy. Furthermore, it can also be used to modifying the genomes of model organisms for studying human......In the last 10 years, we have witnessed a blooming of targeted genome editing systems and applications. The area was revolutionized by the discovery and characterization of the transcription activator-like effector proteins, which are easier to engineer to target new DNA sequences than...... sequence). This ribonucleoprotein complex protects bacteria from invading DNAs, and it was adapted to be used in genome editing. The CRISPR ribonucleic acid (RNA) molecule guides to the specific DNA site the Cas9 nuclease to cleave the DNA target. Two years and more than 1000 publications later, the CRISPR...

  13. Neurosurgery. Fourth edition

    International Nuclear Information System (INIS)

    Simon, L.; Thomas, D.G.T.; Clark, W.K.

    1987-01-01

    The Fourth Edition of this volume in the Operative Surgery Series has been considerably revised to accommodate the many changes which have changed the practice of neurosurgery in the past eight years. There have been advances in technology, such as the wider application of CT scanning, in surgical technique, and in the design of new implantable materials. All these developments have substantially affected both the practice of neurosurgery and the prognosis for the patient and are fully reflected in the new edition

  14. Human Germline Genome Editing

    OpenAIRE

    Ormond, Kelly E.; Mortlock, Douglas P.; Scholes, Derek T.; Bombard, Yvonne; Brody, Lawrence C.; Faucett, W. Andrew; Garrison, Nanibaa’ A.; Hercher, Laura; Isasi, Rosario; Middleton, Anna; Musunuru, Kiran; Shriner, Daniel; Virani, Alice; Young, Caroline E.

    2017-01-01

    With CRISPR/Cas9 and other genome-editing technologies, successful somatic and germline genome editing are becoming feasible. To respond, an American Society of Human Genetics (ASHG) workgroup developed this position statement, which was approved by the ASHG Board in March 2017. The workgroup included representatives from the UK Association of Genetic Nurses and Counsellors, Canadian Association of Genetic Counsellors, International Genetic Epidemiology Society, and US National Society of Gen...

  15. Decimal Classification Editions

    Directory of Open Access Journals (Sweden)

    Zenovia Niculescu

    2009-01-01

    Full Text Available The study approaches the evolution of Dewey Decimal Classification editions from the perspective of updating the terminology, reallocating and expanding the main and auxilary structure of Dewey indexing language. The comparative analysis of DDC editions emphasizes the efficiency of Dewey scheme from the point of view of improving the informational offer, through basic index terms, revised and developed, as well as valuing the auxilary notations.

  16. Is it Feasible to Use Students' Self-reported Step Data in a Local School Policy Process?

    DEFF Research Database (Denmark)

    Bonde, Ane Høstgaard; Bruselius-Jensen, Maria

    2017-01-01

    Objective: We examined students’ self-reported step data and discussed the feasibility of using these data in a local school policy process. Methods: For 5 days during school hours, 281 stu- dents from grades 5–7 participating in a health education program, measured their steps using a pedometer......: Student-collected data showed similar patterns as reported in the literature, and therefore, a feasible perspective could be to use students’ self-reported step data in a local school policy process....

  17. The formulation of public policies for rural youth in Brazil and the constituent elements of social process

    Directory of Open Access Journals (Sweden)

    Sérgio Botton Barcellos

    2015-08-01

    Full Text Available The construction of the research problem occurred in trying to investigate the configuration of public policies for the rural youth and how this political agenda was introduced in the State of the Brazil. The main issue in the research is how the process of configuration of public policies for rural youth in federal government has occurred. The methodology for this study used was qualitative research procedures were triggered participant observation, interviews and documentary analysis. During the research the actors, the formulated policies and rural youth category expressed during this process were highlighted.

  18. On the evaluation of segmentation editing tools

    Science.gov (United States)

    Heckel, Frank; Moltz, Jan H.; Meine, Hans; Geisler, Benjamin; Kießling, Andreas; D’Anastasi, Melvin; dos Santos, Daniel Pinto; Theruvath, Ashok Joseph; Hahn, Horst K.

    2014-01-01

    Abstract. Efficient segmentation editing tools are important components in the segmentation process, as no automatic methods exist that always generate sufficient results. Evaluating segmentation editing algorithms is challenging, because their quality depends on the user’s subjective impression. So far, no established methods for an objective, comprehensive evaluation of such tools exist and, particularly, intermediate segmentation results are not taken into account. We discuss the evaluation of editing algorithms in the context of tumor segmentation in computed tomography. We propose a rating scheme to qualitatively measure the accuracy and efficiency of editing tools in user studies. In order to objectively summarize the overall quality, we propose two scores based on the subjective rating and the quantified segmentation quality over time. Finally, a simulation-based evaluation approach is discussed, which allows a more reproducible evaluation without the need for human input. This automated evaluation complements user studies, allowing a more convincing evaluation, particularly during development, where frequent user studies are not possible. The proposed methods have been used to evaluate two dedicated editing algorithms on 131 representative tumor segmentations. We show how the comparison of editing algorithms benefits from the proposed methods. Our results also show the correlation of the suggested quality score with the qualitative ratings. PMID:26158063

  19. Challenges in Australian policy processes for disinvestment from existing, ineffective health care practices.

    Science.gov (United States)

    Elshaug, Adam G; Hiller, Janet E; Tunis, Sean R; Moss, John R

    2007-10-31

    Internationally, many health care interventions were diffused prior to the standard use of assessments of safety, effectiveness and cost-effectiveness. Disinvestment from ineffective or inappropriately applied practices is a growing priority for health care systems for reasons of improved quality of care and sustainability of resource allocation. In this paper we examine key challenges for disinvestment from these interventions and explore potential policy-related avenues to advance a disinvestment agenda. We examine five key challenges in the area of policy driven disinvestment: 1) lack of resources to support disinvestment policy mechanisms; 2) lack of reliable administrative mechanisms to identify and prioritise technologies and/or practices with uncertain clinical and cost-effectiveness; 3) political, clinical and social challenges to removing an established technology or practice; 4) lack of published studies with evidence demonstrating that existing technologies/practices provide little or no benefit (highlighting complexity of design) and; 5) inadequate resources to support a research agenda to advance disinvestment methods. Partnerships are required to involve government, professional colleges and relevant stakeholder groups to put disinvestment on the agenda. Such partnerships could foster awareness raising, collaboration and improved health outcome data generation and reporting. Dedicated funds and distinct processes could be established within the Medical Services Advisory Committee and Pharmaceutical Benefits Advisory Committee to, a) identify technologies and practices for which there is relative uncertainty that could be the basis for disinvestment analysis, and b) conduct disinvestment assessments of selected item(s) to address existing practices in an analogous manner to the current focus on new and emerging technology. Finally, dedicated funding and cross-disciplinary collaboration is necessary to build health services and policy research capacity

  20. From policy implementation to business process management : Principles for creating flexibility and agility

    NARCIS (Netherlands)

    Gong, Y.; Janssen, M.

    2012-01-01

    Organizations are required to comply with changes in legislation and policy. Yet the implementation of new legislation is often expensive, can have long lead times and is prone to failure. The existing situation significantly constrains policy-making. To improve this, policy makers and policy

  1. Aligning food-processing policies to promote healthier fat consumption in India.

    Science.gov (United States)

    Downs, Shauna M; Marie Thow, Anne; Ghosh-Jerath, Suparna; Leeder, Stephen R

    2015-09-01

    India is undergoing a shift in consumption from traditional foods to processed foods high in sugar, salt and fat. Partially hydrogenated vegetable oils (PHVOs) high in trans-fat are often used in processed foods in India given their low cost and extended shelf life. The World Health Organization has called for the elimination of PHVOs from the global food supply and recommends their replacement with polyunsaturated fat to maximize health benefits. This study examined barriers to replacing industrially produced trans-fat in the Indian food supply and systematically identified potential policy solutions to assist the government in encouraging its removal and replacement with healthier polyunsaturated fat. A combination of food supply chain analysis and semi-structured interviews with key stakeholders was conducted. The main barriers faced by the food-processing sector in terms of reducing use of trans-fat and replacing it with healthier oils in India were the low availability and high cost of oils high in polyunsaturated fats leading to a reliance on palm oil (high in saturated fat) and the low use of those healthier oils in product reformulation. Improved integration between farmers and processors, investment in technology and pricing strategies to incentivize use of healthier oils for product reformulation were identified as policy options. Food processors have trouble accessing sufficient affordable healthy oils for product reformulation, but existing incentives aimed at supporting food processing could be tweaked to ensure a greater supply of healthy oils with the potential to improve population health. © The Author (2014). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  2. Case Studies in Policy Making. Twelfth Edition

    Science.gov (United States)

    2010-01-01

    Annie Sundberg and Ricki Stern, New York Times, 25 July 2007, available at http://movies.nytimes.com/2007/07/25/ movies/25hors.html. 32. Sheryl Gay ...www.defense.gov/news/ newsarticle.aspx?id=52556. 66. Sherry Gay Stolbert, “U.S. Sending Emer- gency Aid to Darfur,” New York Times, 5 January 2009, http...remained the Schonau incident.27 Not everyone in AMAN was as wedded to “the concept” as those at the top. On 1 October, a young intelligence officer in

  3. The Health Policy Process in Vietnam: Going Beyond Kingdon's Multiple Streams TheoryComment on "Shaping the Health Policy Agenda: The Case of Safe Motherhood Policy in Vietnam".

    Science.gov (United States)

    Kane, Sumit

    2016-04-25

    This commentary reflects upon the article along three broad lines. It reflects on the theoretical choices and omissions, particularly highlighting why it is important to adapt the multiple streams framework (MSF) when applying it in a socio-political context like Vietnam's. The commentary also reflects upon the analytical threads tackled by Ha et al; for instance, it highlights the opportunities offered by, and raises questions about the centrality of the Policy Entrepreneur in getting the policy onto the political agenda and in pushing it through. The commentary also dwells on the implications of the article for development aid policies and practices. Throughout, the commentary signposts possible themes for Ha et al to consider for further analysis, and more generally, for future research using Kingdon's multiple streams theory. © 2016 by Kerman University of Medical Sciences.

  4. The application of theories of the policy process to obesity prevention: a systematic review and meta-synthesis.

    Science.gov (United States)

    Clarke, Brydie; Swinburn, Boyd; Sacks, Gary

    2016-10-13

    Theories of the policy process are recommended as tools to help explain both policy stasis and change. A systematic review of the application of such theoretical frameworks within the field of obesity prevention policy was conducted. A meta-synthesis was also undertaken to identify the key influences on policy decision-making. The review identified 17 studies of obesity prevention policy underpinned by political science theories. The majority of included studies were conducted in the United States (US), with significant heterogeneity in terms of policy level (e.g., national, state) studied, areas of focus, and methodologies used. Many of the included studies were methodologically limited, in regard to rigour and trustworthiness. Prominent themes identified included the role of groups and networks, political institutions, and political system characteristics, issue framing, the use of evidence, personal values and beliefs, prevailing political ideology, and timing. The limited application of political science theories indicates a need for future theoretically based research into the complexity of policy-making and multiple influences on obesity prevention policy processes.

  5. HIV/AIDS Policy Making Process in Iran: Analysis of HIV/AIDS Agenda Setting Based on Kingdon's Framework

    Directory of Open Access Journals (Sweden)

    Rahim Khodayari Zarnaq

    2016-12-01

    Full Text Available Background and Objectives : Agenda setting is the process by which certain issues come onto the policy agenda from the much larger number of issues potentially worthy of attention by policy makers. The aim of this study was to deeply understand about how AIDS entered to health policy agenda in Iran. Material and Methods: An exploratory qualitative retrospective study based on multiple streams framework to analyze AIDS agenda setting process, 32 semi-structured interviews were conducted with key informants and stakeholders in Iran and 30 policy documents were reviewed. Data were analyzed using framework analysis method and MAXQDA software. Results : Problem, policy and politics, the three streams of HIV/AIDS in context of Iran were identified and the advent and continuity of multiple streams and their interactions and combination by policy entrepreneurs in couple of streams in policy windows were explained. Conclusion: In this study, the assumption of independence of three streams from each other was doubted. Also, framework has ambiguities in explaining entrepreneurs' act when opening policy windows. Other researchers can modify the framework by learning-by-doing.

  6. Close Reading and Slow Programming — Computer Code as Digital Scholarly Edition

    NARCIS (Netherlands)

    van Zundert, Joris J.

    2016-01-01

    Currently most digital scholarly editions are representational digital documentary editions, largely along the lines described by Elena Pierazzo (2015). Alternative theoretical perspectives take less document centric and more process analytical oriented approaches. Textual scholars have, for

  7. Banning shisha smoking in public places in Iran: an advocacy coalition framework perspective on policy process and change.

    Science.gov (United States)

    Khayatzadeh-Mahani, Akram; Breton, Eric; Ruckert, Arne; Labonté, Ronald

    2017-07-01

    Shisha smoking is a widespread custom in Iran with a rapidly growing prevalence especially among the youth. In this article, we analyze the policy process of enforcing a federal/state ban on shisha smoking in all public places in Kerman Province, Iran. Guided by the Advocacy Coalition Framework (ACF), we investigate how a shisha smoking ban reached the political agenda in 2011, how it was framed by different policy actors, and why no significant breakthrough took place despite its inclusion on the agenda. We conducted a qualitative study using a case study approach. Two main sources of data were employed: face-to-face in-depth interviews and document analysis of key policy texts. We interviewed 24 policy actors from diverse sectors. A qualitative thematic framework, incorporating both inductive and deductive analyses, was employed to analyze our data. We found that the health sector was the main actor pushing the issue of shisha smoking onto the political agenda by framing it as a public health risk. The health sector and its allies advocated enforcement of a federal law to ban shisha smoking in all public places including teahouses and traditional restaurants whereas another group of actors opposed the ban. The pro-ban group was unable to neutralize the strategies of the anti-ban group and to steer the debate towards the health harms of shisha smoking. Our analysis uncovers three main reasons behind the policy stasis: lack of policy learning due to lack of agreement over evidence and related analytical conflicts between the two groups linked to differences in core and policy beliefs; the inability of the pro-ban group to exploit opportunities in the external policy subsystem through generating stronger public support for enforcement of the shisha smoking ban; and the nature of the institutional setting, in particular the autocratic governance of CHFS which contributed to a lack of policy learning within the policy subsystem. Our research demonstrated the utility

  8. A Markov Decision Process Model for Cervical Cancer Screening Policies in Colombia.

    Science.gov (United States)

    Akhavan-Tabatabaei, Raha; Sánchez, Diana Marcela; Yeung, Thomas G

    2017-02-01

    Cervical cancer is the second most common cancer in women around the world, and the human papillomavirus (HPV) is universally known as the necessary agent for developing this disease. Through early detection of abnormal cells and HPV virus types, cervical cancer incidents can be reduced and disease progression prevented. We propose a finite-horizon Markov decision process model to determine the optimal screening policies for cervical cancer prevention. The optimal decision is given in terms of when and what type of screening test to be performed on a patient based on her current diagnosis, age, HPV contraction risk, and screening test results. The cost function considers the tradeoff between the cost of prevention and treatment procedures and the risk of taking no action while taking into account a cost assigned to loss of life quality in each state. We apply the model to data collected from a representative sample of 1141 affiliates at a health care provider located in Bogotá, Colombia. To track the disease incidence more effectively and avoid higher cancer rates and future costs, the optimal policies recommend more frequent colposcopies and Pap tests for women with riskier profiles.

  9. China’s Foreign- and Security-policy Decision-making Processes under Hu Jintao

    Directory of Open Access Journals (Sweden)

    Jean-Pierre Cabestan

    2009-10-01

    Full Text Available Since 1979, foreign- and security-policy-making and implementation processes have gradually and substantially changed. New modes of operation that have consolidated under Hu Jintao, actually took shape under Jiang Zemin in the 1990s, and some, under Deng Xiaoping. While the military’s role has diminished, that of diplomats, experts, and bureaucracies dealing with trade, international economic relations, energy, propaganda and education has increased. Decision making in this area has remained highly centralized and concentrated in the supreme leading bodies of the Chinese Communist Party (CCP. However, China’s globalization and decentralization, as well as the increasing complexity of its international interests, have intensified the need to better coordinate the activities of the various CCP and state organs involved in foreign and security policy; hence, the growing importance of the CCP leading small groups (foreign affairs, national security, Taiwan, etc.. But the rigidity of the current institutional pattern has so far foiled repeated attempts to establish a National Security Council.

  10. [Inclusive education policy: perceptions of managers about the process of changes in Higher Education Institutions].

    Science.gov (United States)

    Pereira, Francilene Jane Rodrigues; dos Santos, Sérgio Ribeiro; da Silva, Cesar Cavalcanti

    2011-01-01

    This is a qualitative descriptive exploratory study, conducted in Higher Education Institutions (HEI) which offers Nursing course, in Joao Pessoa-PB. The study aimed to understand the concept of managers about the need for organizational changes to attend customers with special needs. Four managers participated in the study. A semi-structured interview with guiding questions was used to collect information and to interpret the data we used the method of discourse analysis based on Fiorin. It was noticed that the managers have a concern to meet the demands of inclusive policies, including the adequacy of physical spaces and the pedagogy adopted to meet the students' needs. However, some of them admitted to have little knowledge on how to deal with students with special needs and also mentioned that the institutions do not have an efficient and logistic work which can meet the current legislation of inclusion. We concluded that the process of structural and pedagogical changes is built in a slow and gradual way and it requires an involvement of qualified managers who are committed to execute the policies of inclusion of customers with special needs in a civil and legal way.

  11. Carbon Offsets in California: What Role for Earth Scientists in the Policy Process? (Invited)

    Science.gov (United States)

    Cullenward, D.; Strong, A. L.

    2013-12-01

    some offset protocols award credits for activities that would have occurred anyway; by replacing a company's need to acquire an allowance in the carbon market, critics believe that poorly designed offset protocols increase greenhouse gas emissions. Thus, the effectiveness of the policy approach depends on the scientific integrity of the offset protocols. To date, California has approved offset protocols for emissions reductions in four applications: (1) forestry, (2) urban forestry, (3) livestock, and (4) destruction of ozone-depleting substances. In addition, the State is currently considering protocols that would address (5) methane emissions from mining and (6) greenhouse gas reductions from improved rice cultivation practices. These protocols rely heavily on findings from the environmental and earth sciences communities, especially when the protocol subject involves land use or land use change. Yet, due to budget constraints, the Air Resources Board is relying primarily on third-party protocol developers to design and propose the detailed structures under which offset credits will be issued. Despite the fact that any member of the public may participate in the governance regime that leads to protocol approvals, few scientists or scientific organizations provide input into the policy process. We use case studies from several of the California protocols to illustrate ways scientists can apply their skills to a crucial stage of climate policy development.

  12. Networks of power in digital copyright law and policy political salience, expertise and the legislative process

    CERN Document Server

    Farrand, Benjamin

    2014-01-01

    In this book, Benjamin Farrand employs an interdisciplinary approach that combines legal analysis with political theory to explore the development of copyright law in the EU. Farrand utilises Foucault's concept of Networks of Power and Culpepper's Quiet Politics to assess the adoption and enforcement of copyright law in the EU, including the role of industry representative, cross-border licensing, and judicial approaches to territorial restrictions. Focusing in particular on legislative initiatives concerning copyright, digital music and the internet, Networks of Power in Digital Copyright Law and Policy: Political Salience, Expertise and the Legislative Process demonstrates the connection between copyright law and complex network relationships. This book presents an original socio-political theoretical framework for assessing developments in copyright law that will interest researchers and post-graduate students of law and politics, as well as those more particularly concerned with political theory, EU and c...

  13. GPU Computing Gems Emerald Edition

    CERN Document Server

    Hwu, Wen-mei W

    2011-01-01

    ".the perfect companion to Programming Massively Parallel Processors by Hwu & Kirk." -Nicolas Pinto, Research Scientist at Harvard & MIT, NVIDIA Fellow 2009-2010 Graphics processing units (GPUs) can do much more than render graphics. Scientists and researchers increasingly look to GPUs to improve the efficiency and performance of computationally-intensive experiments across a range of disciplines. GPU Computing Gems: Emerald Edition brings their techniques to you, showcasing GPU-based solutions including: Black hole simulations with CUDA GPU-accelerated computation and interactive display of

  14. Policies and Processes for Social Inclusion: Using EquiFrame and EquIPP for Policy Dialogue Comment on "Are Sexual and Reproductive Health Policies Designed for All? Vulnerable Groups in Policy Documents of Four European Countries and Their Involvement in Policy Development".

    Science.gov (United States)

    MacLachlan, Malcolm; Mannan, Hasheem; Huss, Tessy; Munthali, Alister; Amin, Mutamad

    2015-11-16

    The application of EquiFrame in the analysis of sexual and reproductive health policies by Ivanova et al to a new thematic area, their selection of only some of the Core Concepts of human rights in health service provision and the addition of new vulnerable groups relevant to the purpose of their analysis, are all very welcome developments. We also applaud their application of EquiFrame to policies in countries where it has not previously been used, along with their use of interviews with policy-makers to produce a deeper understanding of policy processes. We argue that clear justification for the inclusion of additional, or replacement of some exiting vulnerable groups within EquiFrame should be accompanied by clear definitions of such groups, along with the evidence-base that justifies their classification as a vulnerable or marginalised group. To illustrate the versatility of EquiFrame, we summarise a range of ways in which it has been used across a number of regions; including a brief Case Study of its use to develop the National Health Policy of Malawi. While EquiFrame focuses on policy content, we preview a new policy analysis tool - Equity and Inclusion in Policy Processes (EquIPP) - which assesses the extent of equity and inclusion in broader policy processes. Together, EquiFrame and EquIPP can be used to help governments and civil society ensure that policies are addressing the much stronger emphasis on social inclusion, now apparent in the Sustainable Development Goals (SDGs). © 2016 by Kerman University of Medical Sciences.

  15. Precision genome editing

    DEFF Research Database (Denmark)

    Steentoft, Catharina; Bennett, Eric P; Schjoldager, Katrine Ter-Borch Gram

    2014-01-01

    of glycobiology, primarily due to their low efficiencies, with resultant failure to impose substantial phenotypic consequences upon the final glycosylation products. Here, we review novel nuclease-based precision genome editing techniques enabling efficient and stable gene editing, including gene disruption......Precise and stable gene editing in mammalian cell lines has until recently been hampered by the lack of efficient targeting methods. While different gene silencing strategies have had tremendous impact on many biological fields, they have generally not been applied with wide success in the field...... by introducing single or double-stranded breaks at a defined genomic sequence. We here compare and contrast the different techniques and summarize their current applications, highlighting cases from the field of glycobiology as well as pointing to future opportunities. The emerging potential of precision gene...

  16. Genome editing: progress and challenges for medical applications

    Directory of Open Access Journals (Sweden)

    Dana Carroll

    2016-11-01

    Full Text Available Editorial summary The development of the CRISPR-Cas platform for genome editing has greatly simplified the process of making targeted genetic modifications. Applications of genome editing are expected to have a substantial impact on human therapies through the development of better animal models, new target discovery, and direct therapeutic intervention.

  17. A Minimal Cognitive Model for Translating and Post-editing

    DEFF Research Database (Denmark)

    Schaeffer, Moritz; Carl, Michael

    2017-01-01

    This study investigates the coordination of reading (input) and writing (output) activities in from-scratch translation and post-editing. We segment logged eye movements and keylogging data into minimal units of reading and writing activity and model the process of post-editing and from-scratch...

  18. State of the environment reporting (SOER) and the policy process in South Africa: Learing for the future

    CSIR Research Space (South Africa)

    Will, C

    2006-01-01

    Full Text Available State of the Environment Report 2005 (Year One). Department of Environmental Affairs and Development Planning, Provincial Government of the Western Cape. Dryzek, J. S (1997) The Politics of the Earth: Environmental Discourses. Oxford University Press...) The Politics of Environmental Discourse. Ecological Modernisation and the Policy Process. Oxford University Press, Oxford. Hajer, M. A and Wagenaar, H. (eds) (2004) Deliberative Policy Analysis: Understanding Governance in the Network Society, Cambridge...

  19. Introduction to Energy - 2nd Edition

    Science.gov (United States)

    Cassedy, Edward S.; Grossman, Peter Z.

    1998-12-01

    Energy issues such as pollution, resource depletion, global warming, nuclear power and waste are problems that demand timely solutions. This book provides a critical examination of the resources, market forces, and social impacts of modern energy production. The book addresses the dilemmas that have arisen due to society's crucial dependence on energy, particularly fossil fuels, and explores the available alternative energy producing technologies. The second edition has increased emphasis on those issues at the forefront of the current energy debate: energy sustainability, climate change, and the radical restructuring of the power industry due to de-regulation. Assuming no prior technical expertise and avoiding complex mathematical formulation, it is directed at a broad readership. The second edition will follow the first in proving especially useful as a textbook for undergraduate programs in Science, Technology and Society (STS), and as a supplementary text in a variety of courses which touch upon energy studies, including environmental and technology policy, environmental, mineral and business law, energy and resource economics. Fully updated second edition of successful first edition that was adopted on Science, Technology and Society courses Provides a critical examination of all aspects of modern energy production for non-technical readers For a broad readership from a variety of backgrounds

  20. Factors affecting evidence-use in food policy-making processes in health and agriculture in Fiji.

    Science.gov (United States)

    Waqa, Gade; Bell, Colin; Snowdon, Wendy; Moodie, Marj

    2017-01-09

    There is limited research on the use of evidence to inform policy-making in the Pacific. This study aims to identify and describe factors that facilitate or limit the use of evidence in food-related policy-making in the Health and Agriculture Ministries in Fiji. Semi-structured face-to-face interviews were conducted with selected policy-makers in two government ministries that were instrumental in the development of food-related policies in Fiji designed to prevent Non-Communicable Diseases (NCDs). Snowball sampling was used to recruit, as key informants, senior policy-makers in management positions such as national advisors and directors who were based at either the national headquarters or equivalent. Interviewees were asked about their experiences in developing food-related or other policies, barriers or facilitators encountered in the policy development and implementation process and the use of evidence. Each interview lasted approximately 45-60 minutes, and was conducted in English. Audio-recorded interviews were transcribed, thematically coded and analyzed using N-Vivo 8.0 software. Thirty-one policy-makers from the Ministry of Health and Medical Services (MoHMS n = 18) and the Ministry of Agriculture (MoA n = 13) in Fiji participated in the study. Whilst evidence is sometimes used in food-related policy-making in both the Health and Agriculture Ministries (including formal evidence such as published research and informal evidence such as personal experiences and opinions), it is not yet embedded as an essential part of the process. Participants indicated that a lack of resources, poor technical support in terms of training, the absence of clear strategies for improving competent use of evidence, procedures regarding engagement with other stakeholders across sectors, varying support from senior managers and limited consultation across sectors were barriers to evidence use. The willingness of organizations to create a culture of using evidence was

  1. The impact of health system governance and policy processes on health services in Iraqi Kurdistan.

    Science.gov (United States)

    Tawfik-Shukor, Ali; Khoshnaw, Hiro

    2010-06-08

    Relative to the amount of global attention and media coverage since the first and second Gulf Wars, very little has been published in the health services research literature regarding the state of health services in Iraq, and particularly on the semi-autonomous region of Kurdistan. Building on findings from a field visit, this paper describes the state of health services in Kurdistan, analyzes their underlying governance structures and policy processes, and their overall impact on the quality, accessibility and cost of the health system, while stressing the importance of reinvesting in public health and community-based primary care. Very little validated, research-based data exists relating to the state of population health and health services in Kurdistan. What little evidence exists, points to a region experiencing an epidemiological polarization, with different segments of the population experiencing rapidly-diverging rates of morbidity and mortality related to different etiological patterns of communicable, non-communicable, acute and chronic illness and disease. Simply put, the rural poor suffer from malnutrition and cholera, while the urban middle and upper classes deal with issues of obesity and Type 2 diabetes. The inequity is exacerbated by a poorly governed, fragmented, unregulated, specialized and heavily privatized system, that not only leads to poor quality of care and catastrophic health expenditures, but also threatens the economic and political stability of the region. There is an urgent need to revisit and clearly define the core values and goals of a future health system, and to develop an inclusive governance and policy framework for change, towards a more equitable and effective primary care-based health system, with attention to broader social determinants of health and salutogenesis. This paper not only frames the situation in Kurdistan in terms of a human rights or special political issue of a minority population, but provides important

  2. The impact of health system governance and policy processes on health services in Iraqi Kurdistan

    Directory of Open Access Journals (Sweden)

    Khoshnaw Hiro

    2010-06-01

    Full Text Available Abstract Background Relative to the amount of global attention and media coverage since the first and second Gulf Wars, very little has been published in the health services research literature regarding the state of health services in Iraq, and particularly on the semi-autonomous region of Kurdistan. Building on findings from a field visit, this paper describes the state of health services in Kurdistan, analyzes their underlying governance structures and policy processes, and their overall impact on the quality, accessibility and cost of the health system, while stressing the importance of reinvesting in public health and community-based primary care. Discussion Very little validated, research-based data exists relating to the state of population health and health services in Kurdistan. What little evidence exists, points to a region experiencing an epidemiological polarization, with different segments of the population experiencing rapidly-diverging rates of morbidity and mortality related to different etiological patterns of communicable, non-communicable, acute and chronic illness and disease. Simply put, the rural poor suffer from malnutrition and cholera, while the urban middle and upper classes deal with issues of obesity and Type 2 diabetes. The inequity is exacerbated by a poorly governed, fragmented, unregulated, specialized and heavily privatized system, that not only leads to poor quality of care and catastrophic health expenditures, but also threatens the economic and political stability of the region. There is an urgent need to revisit and clearly define the core values and goals of a future health system, and to develop an inclusive governance and policy framework for change, towards a more equitable and effective primary care-based health system, with attention to broader social determinants of health and salutogenesis. Summary This paper not only frames the situation in Kurdistan in terms of a human rights or special political

  3. Scorecard for spina bifida research, prevention, and policy - A development process.

    Science.gov (United States)

    Kancherla, Vijaya; Walani, Salimah R; Weakland, Aliki P; Bauwens, Lieven; Oakley, Godfrey P; Warf, Benjamin C

    2017-06-01

    Spina bifida is a serious and largely preventable neural tube birth defect and an important cause of mortality and lifelong disability. The People and Organizations United for Spina Bifida and Hydrocephalus (PUSH!) Global Alliance was formed in 2014 to provide a common platform for various organizations worldwide to raise the visibility of spina bifida and hydrocephalus. In its formative phase, the alliance recognized that in order to accelerate surveillance, prevention, and care for these conditions, there was a need to provide an evidence-based assessment of how nations are performing in specific areas. In this paper, we describe the impetus for, and the process of, developing country-level scorecards for spina bifida surveillance, prevention and care. The PUSH! Executive Committee formulated a comprehensive list of six actionable indicators measuring availability of published studies on population-based folate studies; surveillance of prevalence and mortality; prevention-based policies; access to care; and quality of life associated with spina bifida. Rubrics were developed to score each country on the aforementioned indicators. Country scores were pooled across each indicator and the composite scores ranged between zero and three if there was a need for improvement, four and five if they were in good standing, or six for an excellent status. The scorecard included country-specific recommendations assimilated from the literature and published guidelines to aid policy makers in accelerating surveillance and prevention, and improving the care and quality of life indicators. For comparison, country-level scorecards were grouped by WHO-regions. Score cards were made available publicly through the website "www.pu-sh.org". Copyright © 2017 Elsevier Inc. All rights reserved.

  4. Editing tools. Transcribing and encoding

    NARCIS (Netherlands)

    Spadini, E.

    2015-01-01

    This paper deals with editing tools and editing platforms, i.e. programs used by editors in order to fulfil one or more tasks in the creation of a scholarly digital edition (SDE). Recurring themes in the field of SDEs are the standardization of XML-TEI markup and the success of documentary digital

  5. Nair handbook. 1995 edition

    International Nuclear Information System (INIS)

    1995-01-01

    This Handbook contains general background, administrative and technical information for those participating in the National Arrangements for Incidents involving Radioactivity (NAIR), updating and replacing the previous edition published in 1987. The overriding need for revision was brought about as a result of changes introduced by British Telecom to the telephone numbers of establishments. (UK)

  6. Beginning to edit physics

    Energy Technology Data Exchange (ETDEWEB)

    Murphy, P.W.

    1995-02-01

    A physicist-turned-editor shows you the basics required for copyediting physics papers (physical quantities, symbols, units, scientific notation, the structure of mathematical expressions, the nature of graphs), and points the way to learning enough ``editorial physics`` to begin substantive editing.

  7. MENTAL DEFICIENCY. SECOND EDITION.

    Science.gov (United States)

    HILLIARD, L.T.; KIRMAN, BRIAN H.

    REVISED TO INCLUDE LEGISLATIVE AND ADMINISTRATIVE PROCEDURES NEW IN BRITAIN SINCE THE 1957 EDITION, THE TEXT INCLUDES RECENT ADVANCES IN ETIOLOGY, PATHOLOGY, AND TREATMENT OF MENTAL DEFICIENCY. CONSIDERATION OF THE BACKGROUND OF MENTAL DEFICIENCY INCLUDES HISTORICAL AND LEGAL ASPECTS, THE SOCIAL BACKGROUND OF MENTAL DEFECT, PRENATAL CAUSES OF…

  8. Newspaper Editing: English, Journalism.

    Science.gov (United States)

    Bullock, Johanna

    A course designed to groom editors for the newspaper is presented. Editing copy, copyreading and proofreading, principles of headlining, responsibility of the press, libel and slander laws, and problems of censorship are covered. Course objectives include the following: (1) The student will recognize and correct all newspaper items that do not…

  9. Black Psychology. Third Edition.

    Science.gov (United States)

    Jones, Reginald L., Ed.

    This book is the third edition of a resource for advanced students and professionals in black psychology in the form of 41 papers organized under 5 subheadings. The "overview" section includes one classic article and offers a new, world view paper. A "perspectives" section treats Afrocentric, humanistic, historical,…

  10. The Craft of Editing

    DEFF Research Database (Denmark)

    Moeran, Brian

    To edit is to make a choice, or series of choices. Will I write a rough draft of this essay in longhand, or hammer it out on my computer? If the latter, what font shall I use? Times New Roman, Book Antiqua, or Garamond? Once I get started, what style shall I adopt: realistic, confessional or impr...

  11. Genome Editing in Human Pluripotent Stem Cells.

    Science.gov (United States)

    Carlson-Stevermer, Jared; Saha, Krishanu

    2017-01-01

    Genome editing in human pluripotent stem cells (hPSCs) enables the generation of reporter lines and knockout cell lines. Zinc finger nucleases, transcription activator-like effector nucleases (TALENs), and CRISPR/Cas9 technology have recently increased the efficiency of proper gene editing by creating double strand breaks (DSB) at defined sequences in the human genome. These systems typically use plasmids to transiently transcribe nucleases within the cell. Here, we describe the process for preparing hPSCs for transient expression of nucleases via electroporation and subsequent analysis to create genetically modified stem cell lines.

  12. No link of serotonin 2C receptor editing to serotonin transporter genotype

    NARCIS (Netherlands)

    Lyddon, R.; Cuppen, E.; Haroutunian, V.; Siever, L.J.; Dracheva, S.

    2010-01-01

    RNA editing is a post-transcriptional process, which has the potential to alter the function of encoded proteins. In particular, serotonin 2C receptor (5-HT2cR) mRNA editing can produce 24 protein isoforms of varying functionality. Rodent studies have shown that 5-HT2cR editing is dynamically

  13. Tokamaks (Second Edition)

    International Nuclear Information System (INIS)

    Stott, Peter

    1998-01-01

    The first edition of John Wesson's book on tokamaks, published in 1987, established itself as essential reading for researchers in the field of magnetic confinement fusion: it was an excellent introduction for students to tokamak physics and also a valuable reference work for the more experienced. The second edition, published in 1997, has been completely rewritten and substantially enlarged (680 pages compared with 300). The new edition maintains the aim of providing a simple introduction to basic tokamak physics, but also includes discussion of the substantial advances in fusion research during the past decade. The new book, like its predecessor, is well written and commendable for its clarity and accuracy. In fact many of the chapters are written by a series of co-authors bringing the benefits of a wide range of expertise but, by careful editing, Wesson has maintained a uniformity of style and presentation. The chapter headings and coverage for the most part remain the same - but are expanded considerably and brought up to date. The most substantial change is that the single concluding chapter in the first edition on 'Experiments' has been replaced by three chapters: 'Tokamak experiments' which deals with some of the earlier key experiments plus a selection of recent small and medium-sized devices, 'Large experiments' which gives an excellent summary of the main results from the four large tokamaks - TFTR, JET, JT60/JT60U and DIII-D, and 'The future' which gives a very short (possibly too short in my opinion) account of reactors and ITER. This is an excellent book, which I strongly recommend should have a place - on the desk rather than in the bookshelf - of researchers in magnetic confinement fusion. (book review)

  14. Processes for consensus building and role sharing. Lessons learned from HLW policies in European countries

    International Nuclear Information System (INIS)

    Nagano, Koji

    2003-01-01

    This report attempts to obtain lessons in implementation of HLW management policies for Japan by reviewing past experiences and present status of policy formulation and implementation as well as reflection of public opinions and consensus building of selected European countries, such as Finland, Sweden and others. After examining the situations of those countries, the author derives four key aspects that need to be addressed; separation of nuclear energy policies and HLW policies, fundamental support shared among national public, sense of controllability, and proper scheme of responsibility sharing. (author)

  15. An overview of the United States government's space and science policy-making process

    CERN Multimedia

    CERN. Geneva

    2008-01-01

    A brief overview of the basic elements of the US space and science policy-making apparatus will be presented, focussing on insights into the interactions among the principal organizations, policy-making bodies and individual participants and their respective impact on policy outcomes. Several specific examples will be provided to illustrate the points made, and in the conclusion there will be some observations on current events in the US that may shape the outcome for the near-term future of US space and science policy in several areas.

  16. Genome editing: the breakthrough technology for inherited retinal disease?

    Science.gov (United States)

    Smith, Andrew J; Carter, Stephen P; Kennedy, Breandán N

    2017-10-01

    Genetic alterations resulting in a dysfunctional retinal pigment epithelium and/or degenerating photoreceptors cause impaired vision. These juxtaposed cells in the retina of the posterior eye are crucial for the visual cycle or phototransduction. Deficits in these biochemical processes perturb neural processing of images capturing the external environment. Notably, there is a distinct lack of clinically approved pharmacological, cell- or gene-based therapies for inherited retinal disease. Gene editing technologies are rapidly advancing as a realistic therapeutic option. Areas covered: Recent discovery of endonuclease-mediated gene editing technologies has culminated in a surge of investigations into their therapeutic potential. In this review, the authors discuss gene editing technologies and their applicability in treating inherited retinal diseases, the limitations of the technology and the research obstacles to overcome before editing a patient's genome becomes a viable treatment option. Expert opinion: The ability to strategically edit a patient's genome constitutes a treatment revolution. However, concerns remain over the safety and efficacy of either transplanting iPSC-derived retinal cells following ex vivo gene editing, or with direct gene editing in vivo. Ultimately, further refinements to improve efficacy and safety profiles are paramount for gene editing to emerge as a widely available treatment option.

  17. European experiences as guidelines for public, private and civil sector role redefinition in spatial policy formulation process in Serbia

    Directory of Open Access Journals (Sweden)

    Maksić Milica

    2012-01-01

    Full Text Available The period of post-socialist transition in Serbia brings more complex actors environment compared to socialistic period, while institutional arrangements are not enough developed to actively involve different groups of actors in spatial policy formulation process. In order to gather certain knowledge as guidelines for redefining institutional practices in Serbia, institutional framework of Serbia was compared in this paper with institutional framework of three developed European countries, especially in relation to the roles of public, private and civil sector in spatial policy formulation process. The European countries selected for the analysis are United Kingdom, Netherlands and Germany because of diverse national administrative traditions, so different institutional arrangements could be researched. By comparing institutional framework in Serbia with the ones in developed European countries following questions are researched: which actors are missing in Serbia, what are the ways institutional arrangements for different groups inclusion into spatial policy formulation process are formed, what are the differences between the roles of certain groups of actors in decision-making process. Current roles of actors in spatial policy formulation process in Serbia are reviewed and possible directions for public, private and civil sector role redefinition in Serbia are discussed in accordance with experiences of developed European countries.

  18. Role of the national energy system modelling in the process of the policy development

    Directory of Open Access Journals (Sweden)

    Merse Stane

    2012-01-01

    Full Text Available Strategic planning and decision making, nonetheless making energy policies and strategies, is very extensive process and has to follow multiple and often contradictory objectives. During the preparation of the new Slovenian Energy Programme proposal, complete update of the technology and sector oriented bottom up model of Reference Energy and Environmental System of Slovenia (REES-SLO has been done. During the redevelopment of the REES-SLO model trade-off between the simulation and optimisation approach has been done, favouring presentation of relations between controls and their effects rather than the elusive optimality of results which can be misleading for small energy systems. Scenario-based planning was integrated into the MESAP (Modular Energy System Analysis and Planning environment, allowing integration of past, present and planned (calculated data in a comprehensive overall system. Within the paper, the main technical, economic and environmental characteristics of the Slovenian energy system model REES-SLO are described. This paper presents a new approach in modelling relatively small energy systems which goes beyond investment in particular technologies or categories of technology and allows smooth transition to low carbon economy. Presented research work confirms that transition from environment unfriendly fossil fuelled economy to sustainable and climate friendly development requires a new approach, which must be based on excellent knowledge of alternative possibilities of development and especially awareness about new opportunities in exploitation of energy efficiency and renewable energy sources.

  19. Deep in your room you never leave your room. Edition as a feminist pedagogic tool in the processes of intergenerational translation

    Directory of Open Access Journals (Sweden)

    Maria José Belbel

    2016-07-01

    Full Text Available The author explains the projects she’s worked,  directed  and  collaborated  in the cultural and political field in fortyfive years of activism, from 1971 to the present: the struggle to overthrow Franco’s dictator- ship in the first half of the 70s, linked to a cultural scene which wasn’t so grey in Spain as it is often said. The learning from the pre- vious generation of the sixties, linked to the foucauldian concept of genealogy in music, fashion, performance and the visual arts. The revolutionary arrival of the second wave of feminism in the middle of the 70s. The impact of punk and postpunk in the Spanish movida at the end of the 70s and the beginning of the 80s linked to the Spanish political Transición. The links with Andalucian and Basque young- er generations of activist and visual artists in the 90s. The critical feminist intervention of queer theory in Spanish feminism by the mid and late 90s. Different collaborative and individual projects in grassroots organized feminism Conferences in the first decade of the present century. Edition and translation projects in diverse formats since the 90s to the  present.

  20. Genes (including RNA editing information) - RMG | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us RMG Genes... (including RNA editing information) Data detail Data name Genes (including RNA edi... Site Policy | Contact Us Genes (including RNA editing information) - RMG | LSDB Archive ...

  1. Analyzing Public Discourse: Using Media Content Analysis to Understand the Policy Process

    Science.gov (United States)

    Saraisky, Nancy Green

    2016-01-01

    One of the most basic and obvious sources of data for education policy analysis is text. This article discusses content analysis as an important part of the methodological toolbox for elucidating patterns and trends about education policy. Focusing specifically on media, I show how media content analysis can produce nuanced insights about the ways…

  2. Maintenance policy selection for ships: an investigation using the analytic hierarchy process

    NARCIS (Netherlands)

    Goossens, Adriaan

    2015-01-01

    Maintenance is an important contributor to reach the intended life-time of capital technical assets. How to maintain these assets is gaining increasing attention and relevance. One of the decisions within maintenance is selecting the right maintenance policy: maintenance policy selection (MPS). A

  3. Knowing and Doing Vocational Education and Training Reform: Evidence, Learning and the Policy Process

    Science.gov (United States)

    McGrath, Simon; Lugg, Rosemary

    2012-01-01

    Much of VET policy internationally draws on a toolkit that has been seriously questioned for its logic, international relevance and effectiveness by considerable amounts of academic research. Reflecting primarily on our experiences of leading a complex, multi-country policy study, we develop an account that seeks to explore ways in which the…

  4. Computing Optimal Stationary Policies for Multi-objective Markov Decision Processes

    NARCIS (Netherlands)

    Wiering, M.A.; Jong, E.D. de

    2007-01-01

    This paper describes a novel algorithm called CONMODP for computing Pareto optimal policies for deterministic multi-objective sequential decision problems. CON-MODP is a value iteration based multi-objective dynamic programming algorithm that only computes stationary policies. We observe

  5. Migratory Processes: Contrasts between Immigration Law and Social Policy in Argentina

    Directory of Open Access Journals (Sweden)

    Liliana Madrid

    2011-10-01

    aspects of the new immigration law. Likewise, the article examines the fit between social policies and the prevailing immigration law, and questions the concrete possibilities of access to public policies that guarantee the daily reproduction of the immigrant population, as well as the logic grounding the criteria for the exclusion or inclusion of said population

  6. Revamping the Teacher Evaluation Process. Education Policy Brief. Volume 9, Number 4, Fall 2011

    Science.gov (United States)

    Whiteman, Rodney S.; Shi, Dingjing; Plucker, Jonathan A.

    2011-01-01

    This policy brief explores Senate Enrolled Act 001 (SEA 1), specifically the provisions for how teachers must be evaluated. After a short summary of SEA 1 and its direct changes to evaluation policies and practices, the brief reviews literature in teacher evaluation and highlights important issues for school corporations to consider when selecting…

  7. Fan edits and the legacy of The Phantom Edit

    Directory of Open Access Journals (Sweden)

    Joshua Wille

    2014-09-01

    Full Text Available A fan edit can generally be defined as an alternative version of a film or television text created by a fan. It offers a different viewing experience, much as a song remix offers a different listening experience. The contemporary wave of fan edits has emerged during the remix zeitgeist of digital media and at a time when digital video editing technology has become more affordable and popular. The increasing number of alternative versions of films and the works of revisionist Hollywood filmmakers such as George Lucas have contributed to a greater public understanding of cinema as a fluid medium instead of one that exists in a fixed form. The Phantom Edit (2000, a seminal fan edit based on Lucas's Star Wars Episode I: The Phantom Menace (1999, inspired new ranks of fan editors. However, critics have misunderstood fan edits as merely the work of disgruntled fans. In order to provide a critical and historical basis for studies in fan editing as a creative practice, I examine previous interpretations of fan edits in the context of relevant contemporary works, and I use an annotated chronology of The Phantom Edit to trace its influence on subsequent fan editing communities and uncover their relationship with intellectual property disputes.

  8. Multi-national knowledge strategies, policy and the upgrading process of regions: Revisiting the automotive industry in Ostrava and Shanghai

    NARCIS (Netherlands)

    Tuijl, E. van; Carvalho, L.; Winden, W. van; Jacobs, W.A.A.

    2012-01-01

    This paper revisits how and why new multinational knowledge-based strategies and multi-level governmental policies influence the upgrading process of regions in developing economies. Automotive multinationals traditionally exploited local asset conditions, but it is shown that they have also been

  9. A note on optimal (s,S) and (R,nQ) policies under a stuttering Poisson demand process

    DEFF Research Database (Denmark)

    Larsen, Christian

    2015-01-01

    In this note, a new efficient algorithm is proposed to find an optimal (s, S) replenishment policy for inventory systems with continuous reviews and where the demand follows a stuttering Poisson process (the compound element is geometrically distributed). We also derive three upper bounds...

  10. Preface to Special Edition

    Directory of Open Access Journals (Sweden)

    Renee Nathanson

    2012-04-01

    Full Text Available Given that reading comprehension is at the forefront of global literacy discourse, this special edition of Per Linguam, the first number that is also published online, features a collection of articles that cover different aspects of reading comprehension and instruction, such as, strategies for comprehending texts, metacognitive awareness, the reciprocity of assessment and comprehension instruction and socio-affective factors that influence comprehension.

  11. UN-EDITED VERSION

    Indian Academy of Sciences (India)

    57

    1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 25. 26. 27. 28. 29. 30. 31. 32. 33. 34. 35. 36. 37. 38. 39. 40. 41. 42. 43. 44. 45. 46. 47. 48. 49. 50. 51. 52. 53. 54. 55. 56. 57. 58. 59. 60. 61. 62. 63. 64. 65. UN-EDITED VERSION ...

  12. Accelerating research through reagent repositories: the genome editing example.

    Science.gov (United States)

    Joung, J Keith; Voytas, Daniel F; Kamens, Joanne

    2015-11-20

    Keith Joung, Dan Voytas and Joanne Kamens share insights into how the genome editing field was advanced by early access to biological resources and the role in this process that plasmid repositories play.

  13. The Evaluation of the Effectiveness of Counterterrorism Policies on the PKK-inflicted Violence during the Democratization Process of Turkey

    OpenAIRE

    Irfan Ciftci; Sedat Kula

    2015-01-01

    This study tries to explore the relationship between soft-line governmental policy interventions of Turkey and the responses of the PKK (The Kurdistan Workers’ Party) by using time series data from 1995 to 2010. The negative binomial specifications for two models, the number of incidents and the number casualties are used. The aggregated impact of soft-line policies on the level of violence is found to be positive and significant. In one hand, Turkey’s EU accession process had a decreasing im...

  14. ABOUT THE ROLE OF GOVERNMENT SPENDING IN THE PROCESSES OF FINANCIAL POLICY

    Directory of Open Access Journals (Sweden)

    V. Ye. Vlasiuk

    2008-08-01

    Full Text Available The paper deals with the analyses of financial system conditions through the state expenses. The factors of the state regulation influence on forming the financial policy are analyzed.

  15. Engaging China in the International Export Control Process: Options for U.S. Policy

    National Research Council Canada - National Science Library

    Goldman, Charles

    1995-01-01

    .... objectives and potential policy initiatives toward that end. Using knowledge about the operation of the Chinese bureaucratic system, especially in defense related research and development, the briefing describes a number of strategy options for U.S...

  16. Global Bathymetry: Machine Learning for Data Editing

    Science.gov (United States)

    Sandwell, D. T.; Tea, B.; Freund, Y.

    2017-12-01

    The accuracy of global bathymetry depends primarily on the coverage and accuracy of the sounding data and secondarily on the depth predicted from gravity. A main focus of our research is to add newly-available data to the global compilation. Most data sources have 1-12% of erroneous soundings caused by a wide array of blunders and measurement errors. Over the years we have hand-edited this data using undergraduate employees at UCSD (440 million soundings at 500 m resolution). We are developing a machine learning approach to refine the flagging of the older soundings and provide automated editing of newly-acquired soundings. The approach has three main steps: 1) Combine the sounding data with additional information that may inform the machine learning algorithm. The additional parameters include: depth predicted from gravity; distance to the nearest sounding from other cruises; seafloor age; spreading rate; sediment thickness; and vertical gravity gradient. 2) Use available edit decisions as training data sets for a boosted tree algorithm with a binary logistic objective function and L2 regularization. Initial results with poor quality single beam soundings show that the automated algorithm matches the hand-edited data 89% of the time. The results show that most of the information for detecting outliers comes from predicted depth with secondary contributions from distance to the nearest sounding and longitude. A similar analysis using very high quality multibeam data shows that the automated algorithm matches the hand-edited data 93% of the time. Again, most of the information for detecting outliers comes from predicted depth secondary contributions from distance to the nearest sounding and longitude. 3) The third step in the process is to use the machine learning parameters, derived from the training data, to edit 12 million newly acquired single beam sounding data provided by the National Geospatial-Intelligence Agency. The output of the learning algorithm will be

  17. Tokamaks - Third Edition

    International Nuclear Information System (INIS)

    Rogister, A L

    2004-01-01

    John Wesson's well known book, now re-edited for the third time, provides an excellent introduction to fusion oriented plasma physics in tokamaks. The author's task was a very challenging one, for a confined plasma is a complex system characterised by a variety of dimensionless parameters and its properties change qualitatively when certain threshold values are reached in this multi-parameter space. As a consequence, theoretical description is required at different levels, which are complementary: particle orbits, kinetic and fluid descriptions, but also intuitive and empirical approaches. Theory must be carried out on many fronts: equilibrium, instabilities, heating, transport etc. Since the properties of the confined plasma depend on the boundary conditions, the physics of plasmas along open magnetic field lines and plasma surface interaction processes must also be accounted for. Those subjects (and others) are discussed in depth in chapters 2-9. Chapter 1 mostly deals with ignition requirements and the tokamak concept, while chapter 14 provides a list of useful relations: differential operators, collision times, characteristic lengths and frequencies, expressions for the neoclassical resistivity and heat conduction, the bootstrap current etc. The presentation is sufficiently broad and thorough that specialists within tokamak research can either pick useful and up-to-date information or find an authoritative introduction into other areas of the subject. It is also clear and concise so that it should provide an attractive and accurate initiation for those wishing to enter the field and for outsiders who would like to understand the concepts and be informed about the goals and challenges on the horizon. Validation of theoretical models requires adequately resolved experimental data for the various equilibrium profiles (clearly a challenge in the vicinity of transport barriers) and the fluctuations to which instabilities give rise. Chapter 10 is therefore devoted to

  18. Crossing institutional boundaries: mapping the policy process for improved control of endemic and neglected zoonoses in sub-Saharan Africa.

    Science.gov (United States)

    Okello, Anna; Welburn, Susan; Smith, James

    2015-07-01

    The recent adoption of the World Health Assembly Resolution 66.12 for neglected tropical diseases (NTDs) in May 2013 is an important turning point for advocacy regarding a number of endemic zoonotic infections, defined by the World Health Organization as the neglected zoonotic diseases (NZDs). In addition to NTD-listed zoonoses such as rabies, echinococcosis (hydatid disease), leishmaniasis, Human African trypanosomiasis (sleeping sickness) and Taenia solium cysticercosis, the NZDs also include important bacterial zoonoses such as anthrax, bovine tuberculosis and brucellosis. To date, analysis of the processes that prioritize, develop and deliver zoonoses control programmes in many low- and middle-income countries is lacking, despite its potential to highlight significant evidence gaps and institutional constraints to the intersectoral approach required for their control. Policy process analysis was conducted via a series of semi-structured interviews with key policy actors within various ministries and institutes in Uganda and Nigeria. The study concluded that despite the rhetoric around 'linear' models of health policy development promoting consultation with a wide range of national stakeholders, the decision-making process for zoonotic disease control appears instead overtly influenced by the external political economy of trending pandemic threats, often overlooking national and regional zoonoses priorities. The inclusion of political systems remains a key factor in the zoonoses analysis matrix, enhancing our understanding of the intersectoral and transdisciplinary approaches required for their control. The authors consider policy process analysis to be a fundamental first step of any attempt to holistically strengthen human and animal health systems in a development context, particularly regarding the promotion of integrated control policies for regionally important zoonoses under the growing One Health movement. Published by Oxford University Press in

  19. Revising and editing for translators

    CERN Document Server

    Mossop, Brian

    2014-01-01

    Revising and Editing for Translators provides guidance and learning materials for translation students learning to edit texts written by others, and professional translators wishing to improve their self-revision ability or learning to revise the work of others. Editing is understood as making corrections and improvements to texts, with particular attention to tailoring them to the given readership. Revising is this same task applied to draft translations. The linguistic work of editors and revisers is related to the professional situations in which they work. Mossop offers in-depth coverage of a wide range of topics, including copyediting, style editing, structural editing, checking for consistency, revising procedures and principles, and translation quality assessment. This third edition provides extended coverage of computer aids for revisers, and of the different degrees of revision suited to different texts. The inclusion of suggested activities and exercises, numerous real-world examples, a proposed gra...

  20. Knowledge brokering between researchers and policymakers in Fiji to develop policies to reduce obesity: a process evaluation.

    Science.gov (United States)

    Waqa, Gade; Mavoa, Helen; Snowdon, Wendy; Moodie, Marj; Schultz, Jimaima; McCabe, Marita; Kremer, Peter; Swinburn, Boyd

    2013-07-01

    The importance of using research evidence in decisionmaking at the policy level has been increasingly recognized. However, knowledge brokering to engage researchers and policymakers in government and non-government organizations is challenging. This paper describes and evaluates the knowledge exchange processes employed by the Translational Research on Obesity Prevention in Communities (TROPIC) project that was conducted from July 2009 to April 2012 in Fiji. TROPIC aimed to enhance: the evidence-informed decisionmaking skills of policy developers; and awareness and utilization of local and other obesity-related evidence to develop policies that could potentially improve the nation's food and physical activity environments. The specific research question was: Can a knowledge brokering approach advance evidence-informed policy development to improve eating and physical activity environments in Fiji. The intervention comprised: recruiting organizations and individuals; mapping policy environments; analyzing organizational capacity and support for evidence-informed policymaking (EIPM); developing EIPM skills; and facilitating development of evidence-informed policy briefs. Flexible timetabling of activities was essential to accommodate multiple competing priorities at both individual and organizational levels. Process diaries captured the duration, frequency and type of each interaction and/or activity between the knowledge brokering team and participants or their organizations. Partnerships were formalized with high-level officers in each of the six participating organization. Participants (n = 49) developed EIPM skills (acquire, assess, adapt and apply evidence) through a series of four workshops and applied this knowledge to formulate briefs with ongoing one-to-one support from TROPIC team members. A total of 55% of participants completed the 12 to18 month intervention, and 63% produced one or more briefs (total = 20) that were presented to higher

  1. Process, paper policy and practice : a case study of the introduction of a formal extension policy in Queensland, Australia 1987 - 1994

    NARCIS (Netherlands)

    Coutts, J.A.

    1994-01-01

    This study explores the policy element of public sector agricultural extension. It was contended that this policy element lacked an adequate framework. Without such a framework, there was a risk that major policy - or operational - issues would be neglected in policy formulation. The study

  2. The influence of knowledge on the public policy making process: the case of renewable energies in Midi Pyrenees

    International Nuclear Information System (INIS)

    Behar, L.

    2012-01-01

    Even though energy policy makers were novices when wind power was introduced in the Midi Pyrenees region, the situation had changed when the photovoltaic was implemented. The new challenges policy makers experimented about the wind power and their opponents, the wood energy and the primacy of the wood's industrials, the photovoltaic and the preservation of the agricultural lands, fostered their learning and gradually lead them to change their perception of inherent issues. The coalitions forged between technical experts and policy makers unbind along the progressive empowerment of the formers. Shared between different forms of knowledge, however, the resources needed to implement renewable energies projects cannot be reduced to the technical dimension. Local knowledge and engineering knowledge increasingly compete with expert knowledge. This evolution corresponds to a policy arrangement change. Since the dynamic but also the elements that compose this political system change, a new reality gradually emerges. This whole process will be the main concern of this thesis. We will finally notice that there are some differences between the implementation of these renewable energies among the territories but also among the three forms of renewable energies we analyze. This means that although renewable energy policy are based on interactions between actors' resources, discourse and rules, they also emerge from the action of intermediates actors, and from the characteristic of each territories in which they are implemented. (author)

  3. REDIdb: the RNA editing database.

    Science.gov (United States)

    Picardi, Ernesto; Regina, Teresa Maria Rosaria; Brennicke, Axel; Quagliariello, Carla

    2007-01-01

    The RNA Editing Database (REDIdb) is an interactive, web-based database created and designed with the aim to allocate RNA editing events such as substitutions, insertions and deletions occurring in a wide range of organisms. The database contains both fully and partially sequenced DNA molecules for which editing information is available either by experimental inspection (in vitro) or by computational detection (in silico). Each record of REDIdb is organized in a specific flat-file containing a description of the main characteristics of the entry, a feature table with the editing events and related details and a sequence zone with both the genomic sequence and the corresponding edited transcript. REDIdb is a relational database in which the browsing and identification of editing sites has been simplified by means of two facilities to either graphically display genomic or cDNA sequences or to show the corresponding alignment. In both cases, all editing sites are highlighted in colour and their relative positions are detailed by mousing over. New editing positions can be directly submitted to REDIdb after a user-specific registration to obtain authorized secure access. This first version of REDIdb database stores 9964 editing events and can be freely queried at http://biologia.unical.it/py_script/search.html.

  4. Genome Editing Tools in Plants

    Directory of Open Access Journals (Sweden)

    Tapan Kumar Mohanta

    2017-12-01

    Full Text Available Genome editing tools have the potential to change the genomic architecture of a genome at precise locations, with desired accuracy. These tools have been efficiently used for trait discovery and for the generation of plants with high crop yields and resistance to biotic and abiotic stresses. Due to complex genomic architecture, it is challenging to edit all of the genes/genomes using a particular genome editing tool. Therefore, to overcome this challenging task, several genome editing tools have been developed to facilitate efficient genome editing. Some of the major genome editing tools used to edit plant genomes are: Homologous recombination (HR, zinc finger nucleases (ZFNs, transcription activator-like effector nucleases (TALENs, pentatricopeptide repeat proteins (PPRs, the CRISPR/Cas9 system, RNA interference (RNAi, cisgenesis, and intragenesis. In addition, site-directed sequence editing and oligonucleotide-directed mutagenesis have the potential to edit the genome at the single-nucleotide level. Recently, adenine base editors (ABEs have been developed to mutate A-T base pairs to G-C base pairs. ABEs use deoxyadeninedeaminase (TadA with catalytically impaired Cas9 nickase to mutate A-T base pairs to G-C base pairs.

  5. A REVIEW ON GENOME EDITING

    OpenAIRE

    Akshay Patil, Latesh Patil, H. P. Suryawanshi, S. P. Pawar

    2017-01-01

    The Present Review report contains the information about Genome Editing. In this report genome editing is illustrated at the basic level for better understanding. It contains History of Genome Editing from 1800 to Current day i.e. from concept of DNA till current time. Genome editing is an technique to make every human smarter not our choice, by customizing next generation the way we want it to be like to be look and also the intellectual capacity. In this Concept, the viral Immunity is used ...

  6. From forest landscape to agricultural landscape in the developing tropical country of Malaysia: pattern, process, and their significance on policy.

    Science.gov (United States)

    Abdullah, Saiful Arif; Hezri, Adnan A

    2008-11-01

    Agricultural expansion and deforestation are spatial processes of land transformation that impact on landscape pattern. In peninsular Malaysia, the conversion of forested areas into two major cash crops--rubber and oil palm plantations--has been identified as driving significant environmental change. To date, there has been insufficient literature studying the link between changes in landscape patterns and land-related development policies. Therefore, this paper examines: (i) the links between development policies and changes in land use/land cover and landscape pattern and (ii) the significance and implications of these links for future development policies. The objective is to generate insights on the changing process of land use/land cover and landscape pattern as a functional response to development policies and their consequences for environmental conditions. Over the last century, the development of cash crops has changed the country from one dominated by natural landscapes to one dominated by agricultural landscapes. But the last decade of the century saw urbanization beginning to impact significantly. This process aligned with the establishment of various development policies, from land development for agriculture between the mid 1950s and the 1970s to an emphasis on manufacturing from the 1980s onward. Based on a case study in Selangor, peninsular Malaysia, a model of landscape pattern change is presented. It contains three stages according to the relative importance of rubber (first stage: 1900--1950s), oil palm (second stage: 1960s--1970s), and urban (third stage: 1980s--1990s) development that influenced landscape fragmentation and heterogeneity. The environmental consequences of this change have been depicted through loss of biodiversity, geohazard incidences, and the spread of vector-borne diseases. The spatial ecological information can be useful to development policy formulation, allowing diagnosis of the country's "health" and sustainability. The

  7. Understanding farmers' strategic decision-making processes and the implications for biodiversity conservation policy.

    Science.gov (United States)

    Farmar-Bowers, Quentin; Lane, Ruth

    2009-02-01

    The conservation of biodiversity is an important issue world wide and in Australia the maintenance of native biodiversity on farms makes an important contribution to overall conservation objectives. This paper seeks to explain Australian farmers' rationale for maintaining biodiversity on their farms for personal as opposed to business reasons by developing a decision-systems theory from in-depth interviews. This difference has implications for policy development. The decision-systems theory is divided into two main sections. The first section contains five parts. (1) A hierarchy of motivation stories, (2) the concept of suitability and availability of opportunities, (3) a hierarchy of three decision-systems, (4) the concept of personal career paths, (5) the concept of Lenses. The second section contains one part, a policy classification system called 'boxes of influence' that suggests how policy developers can use the information in the first section to develop new biodiversity conservation policy. The paper suggests that decision-systems theory could be used to shed new light on current trends in agriculture and become an important investigative tool for policy development concerning the conservation of biodiversity on farms.

  8. The process of construction of evidence: An analysis of the use of indicators in two decisions of innovation policy

    Energy Technology Data Exchange (ETDEWEB)

    Boavida, N.; Moniz, A.; Laranja, M.

    2016-07-01

    Despite increasing calls for evidence-based policies, knowledge about the practical use of evidences remains limited. This paper studies the process of construction of evidences in decisions of innovation policy to understand how evidences were used. It analysis the use of indicators and other evidences through interviews conducted to inquire about the two decisions: an electric mobility policy and a nanotechnology laboratory. Results show indicators and other evidences were brought to decision processes according to their availability and capacity to support the different interests of the actors and the stakeholders. Their role was influenced by the particular situation of the decision makers. More importantly, the use of persuasive analytical evidences appears to be related with the adversity of the policy context. In addition, research suggests that indicators are one tool among others to foster innovation decisions. In fact, the relatively minor instrumental role of indicators suggests that indicators are mostly a complementary instrument of decision. When used relevantly, indicators can offer support to a decision. But there are other significant influences that need to be taken into account to understand the specific role indicators and other evidences play, such as the social relations of the decision makers and their emotional-intuitive decisions. (Author)

  9. The Health Policy Process in Vietnam: Going Beyond Kingdon’s Multiple Streams Theory

    Science.gov (United States)

    Kane, Sumit

    2016-01-01

    This commentary reflects upon the article along three broad lines. It reflects on the theoretical choices and omissions, particularly highlighting why it is important to adapt the multiple streams framework (MSF) when applying it in a socio-political context like Vietnam’s. The commentary also reflects upon the analytical threads tackled by Ha et al; for instance, it highlights the opportunities offered by, and raises questions about the centrality of the Policy Entrepreneur in getting the policy onto the political agenda and in pushing it through. The commentary also dwells on the implications of the article for development aid policies and practices. Throughout, the commentary signposts possible themes for Ha et al to consider for further analysis, and more generally, for future research using Kingdon’s multiple streams theory. PMID:27694671

  10. Public policy for children in Brazil – the process of implementation of a new model

    Directory of Open Access Journals (Sweden)

    Rodrigo Stumpf González

    2015-06-01

    Full Text Available Recently happened the 25th anniversary of the approval of the Child and Adolescent Statute. Which goals are achieved? What changed? This work analyses the Brazilian case in implementation of a new paradigm of children rights and his impact in the definition of aconcrete agenda of public policies, doing an evaluation of the new model and the changes, with focus of the development of a agenda of policies in four subjects: creation of councils, attention for the young lawbreakers, exploitation of child labour and sexual violence against children. At the end are discussed motivation for partial success in implementation of the agenda and responsibilities of the institutional actors involved.

  11. Changing the malaria treatment protocol policy in Timor-Leste: an examination of context, process, and actors’ involvement

    Science.gov (United States)

    2013-01-01

    In 2007 Timor-Leste, a malaria endemic country, changed its Malaria Treatment Protocol for uncomplicated falciparum malaria from sulphadoxine-pyrimethamine to artemether-lumefantrine. The change in treatment policy was based on the rise in morbidity due to malaria and perception of increasing drug resistance. Despite a lack of nationally available evidence on drug resistance, the Ministry of Health decided to change the protocol. The policy process leading to this change was examined through a qualitative study on how the country developed its revised treatment protocol for malaria. This process involved many actors and was led by the Timor-Leste Ministry of Health and the WHO country office. This paper examines the challenges and opportunities identified during this period of treatment protocol change. PMID:23672371

  12. An interoperable architecture and principles for implementing strategy and policy in operational processes

    NARCIS (Netherlands)

    Gong, Y.; Janssen, M.

    2013-01-01

    In today's economy managers expect new strategies and policies to be implemented quickly. Yet practice shows that current systems are not able to implement changes within a short time frame. Nowadays a variety of technologies including semantic web services, business rules and software agents are

  13. Children's Friendships in Diverse Primary Schools: Teachers and the Processes of Policy Enactment

    Science.gov (United States)

    Vincent, Carol; Neal, Sarah; Iqbal, Humera

    2016-01-01

    Drawing on data from a project exploring children's and adults' friendships across social class and ethnic difference, this paper focuses on the enactment of national and institutional policy around children's friendships as realized in three primary schools in diverse urban areas in London. Through a focus on the way in which social and emotional…

  14. Shifts in EU cohesion policy and processes of peripheralization: a view from Central Eastern Europe

    NARCIS (Netherlands)

    Faragó, L.; Varró, K.

    2016-01-01

    The increasing dominance of neoliberalism as the key steering mechanism of the European Union (EU) since the early 1990s has implied the competitiveness-oriented reshaping of cohesion policy. The aim of this paper is to initiate a debate from a critical political economic perspective on the

  15. Regional Integrated Assessments in Support of Decision-making: Process, Product, and Policy

    Science.gov (United States)

    Luers, A. L.; Hayhoe, K.

    2006-12-01

    Regional integrated climate assessments are increasingly viewed as critical for informing sound climate policy. Yet, the scientific information in many assessments often is not effectively transformed in to policies to protect the environment. Why are some assessments more effective at informing policies than others? We will provide some insight into this question by describing the lessons learned from a series of regional assessments organized by the Union of Concerned Scientists (UCS). Working with independent experts in the global change research community, UCS has produced assessments in three regions of the US California, the Great Lakes, and the Gulf Coast. The reports from each of these assessments continue to be used by local, state and regional decision-makers in related management and policy initiatives. We attribute the success of these assessments in motivating and supporting climate-related decisions to four factors: (1) credibility, attained both through scientific peer-review and by engaging local scientific and community leaders; (2) regional relevance of assessment focus areas; (3) accessible presentation of the results to non-technical audiences; and (4) wide communication and distribution of the report to the media, the public, civic groups, and public officials.

  16. The planning process regarding inflow in GP training in the Netherlands: between policy and practice.

    NARCIS (Netherlands)

    Greuningen, M. van; Batenburg, R.; Velden, L. van der

    2011-01-01

    Context: Shortages and oversupply of health care personnel are a major concern of policy makers and professional bodies. It is commonly acknowledged manpower planning can be an important instrument to control these fluctuations. In the Netherlands, there has been a long period of experience with

  17. Instrumental analysis, second edition

    International Nuclear Information System (INIS)

    Christian, G.D.; O'Reilly, J.E.

    1988-01-01

    The second edition of Instrumental Analysis is a survey of the major instrument-based methods of chemical analysis. It appears to be aimed at undergraduates but would be equally useful in a graduate course. The volume explores all of the classical quantitative methods and contains sections on techniques that usually are not included in a semester course in instrumentation (such as electron spectroscopy and the kinetic methods). Adequate coverage of all of the methods contained in this book would require several semesters of focused study. The 25 chapters were written by different authors, yet the style throughout the book is more uniform than in the earlier edition. With the exception of a two-chapter course in analog and digital circuits, the book purports to de-emphasize instrumentation, focusing more on the theory behind the methods and the application of the methods to analytical problems. However, a detailed analysis of the instruments used in each method is by no means absent. The book has the favor of a user's guide to analysis

  18. Quantitative Seismology, Second Edition

    Science.gov (United States)

    Lay, Thorne

    As recently as 1980, anyone seeking a rigorous treatment of the fundamentals of elastodynamics relevant to the rapidly maturing field of seismology had to delve into a host of primary sources, some of which were rather obscure or difficult to obtain. Classical texts in this field tended to focus on limited topics and to treat some areas either superficially or in excessive depth. Graduate education in the field of seismology tended to reflect local faculty expertise and interests, often with compendia of handwritten notes, inconsistent notation, and variable generality. That situation was dramatically changed with the appearance of the first edition of Quantitative Seismology, a two-volume set that distilled the key foundations of elastodynamics for linear elastic materials into an accessible and satisfyingly thorough presentation of seismological theory. The adoption of a uniform, consistent notation in which many previous contributions were represented was perhaps as great of a contribution to the field as the many conceptual insights revealed by the authors' treatment of the topic. That work has become a disciplinary standard, with tremendous impact on the education of students and the research of advanced practitioners in the field. No subsequent text has supplanted this cornerstone of the discipline, but over time the second volume went out of print and a second edition became necessary.

  19. Natural Hazards, Second Edition

    Science.gov (United States)

    Rouhban, Badaoui

    Natural disaster loss is on the rise, and the vulnerability of the human and physical environment to the violent forces of nature is increasing. In many parts of the world, disasters caused by natural hazards such as earthquakes, floods, landslides, drought, wildfires, intense windstorms, tsunami, and volcanic eruptions have caused the loss of human lives, injury, homelessness, and the destruction of economic and social infrastructure. Over the last few years, there has been an increase in the occurrence, severity, and intensity of disasters, culminating with the devastating tsunami of 26 December 2004 in South East Asia.Natural hazards are often unexpected or uncontrollable natural events of varying magnitude. Understanding their mechanisms and assessing their distribution in time and space are necessary for refining risk mitigation measures. This second edition of Natural Hazards, (following a first edition published in 1991 by Cambridge University Press), written by Edward Bryant, associate dean of science at Wollongong University, Australia, grapples with this crucial issue, aspects of hazard prediction, and other issues. The book presents a comprehensive analysis of different categories of hazards of climatic and geological origin.

  20. With this Special Edition

    Directory of Open Access Journals (Sweden)

    Oscar Antonio Martínez Molina

    2017-02-01

    Full Text Available With this Special Edition, the refereed Scientific Magazine, published in February 2017, presents a nourished and multidisciplinary theme, from the relationship of Environmental Education, in this ecological sharing man-environment; the social responsibility from the Management environment and the motivational values ​​conducive to the teaching performance in the different educational levels. Twenty-five (25 articles, generated from research production in university environments at the International level, are a signature of the quality of articles / essays presented in this Special Edition. Several reasons motivate the literary pen of our authors, adjusting to the rhythm of the times and the use of new technologies; and in correspondence with the care of the environment, this way of disseminating and making visible the scientific contents of humanistic and social court, support the care and protection of the forests, being an online production, in the Cloud. Thanks to the support of the Instituto Internacional de Investigación y Desarrollo Tecnológico Educativo INDTEC, CA, Scientific Magazine has been able to develop from the cooperative work of the people who compose its different committees: Editorial Academic Committee, Academic Scientific Committee and the Arbitrators in the review and valuation of the quality of the articles. With these assets, the Scientific Magazine, opening to the general public and especially to the academic new intellectual horizons.

  1. Annotation in Digital Scholarly Editions

    NARCIS (Netherlands)

    Boot, P.; Haentjens Dekker, R.

    2016-01-01

    Annotation in digital scholarly editions (of historical documents, literary works, letters, etc.) has long been recognized as an important desideratum, but has also proven to be an elusive ideal. In so far as annotation functionality is available, it is usually developed for a single edition and

  2. Fundamentals of Welding. Teacher Edition [and] Student Edition [and] Student Workbook. Second Edition.

    Science.gov (United States)

    Fortney, Clarence; Gregory, Mike; New, Larry

    Teacher and student editions and a student workbook for fundamentals of welding comprise the first of six in a series of competency-based instructional materials for welding programs. Introductory pages in the teacher edition are training and competency profile, instructional/task analysis, basic skills icons and classifications, basic skills…

  3. Oxyacetylene Welding and Oxyfuel Cutting. Third Edition. Teacher Edition [and] Student Edition [and] Student Workbook.

    Science.gov (United States)

    Knapp, John; Harper, Eddie

    This Oklahoma curriculum guide, which includes a teacher edition, a student edition, and a student workbook, provides three units for a course on oxyacetylene welding, oxyfuel cutting, and cutting done with alternative fuels such as MAPP, propane, and natural gas. The three units are: "Oxyacetylene Welding"; "Oxyfuel Cutting";…

  4. South African Risk and Vulnerability Atlas: Understanding the Social & Environmental Implications of Global Change. 2nd edition

    CSIR Research Space (South Africa)

    Mambo, Julia

    2017-12-01

    Full Text Available edition in several respects and comprises more chapters, which are more detailed and incorporate feedback received from the first edition. The selection of the contributing authors to the second edition atlas was based on the experiences and knowledge... MDG Millennium Development Goal NCCRP National Climate Change Response Policy NFA National Forests Act of 1998 NPC National Planning Commission NRE Natural Resources and Environment (unit) NWA National Water Act (No. 36 of 1998) PCIS Principles...

  5. Approximating Tree Edit Distance through String Edit Distance

    OpenAIRE

    Akutsu, Tatsuya; Fukagawa, Daiji; Takasu, Atsuhiro

    2010-01-01

    We present an algorithm to approximate edit distance between two ordered and rooted trees of bounded degree. In this algorithm, each input tree is transformed into a string by computing the Euler string, where labels of some edges in the input trees are modified so that structures of small subtrees are reflected to the labels. We show that the edit distance between trees is at least 1/6 and at most O(n 3/4) of the edit distance between the transformed strings, where n is the maximum size of t...

  6. Assessing the influence of knowledge translation platforms on health system policy processes to achieve the health millennium development goals in Cameroon and Uganda: a comparative case study.

    Science.gov (United States)

    Ongolo-Zogo, Pierre; Lavis, John N; Tomson, Goran; Sewankambo, Nelson K

    2018-05-01

    There is a scarcity of empirical data on the influence of initiatives supporting evidence-informed health system policy-making (EIHSP), such as the knowledge translation platforms (KTPs) operating in Africa. To assess whether and how two KTPs housed in government-affiliated institutions in Cameroon and Uganda have influenced: (1) health system policy-making processes and decisions aiming at supporting achievement of the health millennium development goals (MDGs); and (2) the general climate for EIHSP. We conducted an embedded comparative case study of four policy processes in which Evidence Informed Policy Network (EVIPNet) Cameroon and Regional East African Community Health Policy Initiative (REACH-PI) Uganda were involved between 2009 and 2011. We combined a documentary review and semi structured interviews of 54 stakeholders. A framework-guided thematic analysis, inspired by scholarship in health policy analysis and knowledge utilization was used. EVIPNet Cameroon and REACH-PI Uganda have had direct influence on health system policy decisions. The coproduction of evidence briefs combined with tacit knowledge gathered during inclusive evidence-informed stakeholder dialogues helped to reframe health system problems, unveil sources of conflicts, open grounds for consensus and align viable and affordable options for achieving the health MDGs thus leading to decisions. New policy issue networks have emerged. The KTPs indirectly influenced health policy processes by changing how interests interact with one another and by introducing safe-harbour deliberations and intersected with contextual ideational factors by improving access to policy-relevant evidence. KTPs were perceived as change agents with positive impact on the understanding, acceptance and adoption of EIHSP because of their complementary work in relation to capacity building, rapid evidence syntheses and clearinghouse of policy-relevant evidence. This embedded case study illustrates how two KTPs influenced

  7. Towards environmentally sustainable human behaviour: targeting non-conscious and conscious processes for effective and acceptable policies.

    Science.gov (United States)

    Marteau, Theresa M

    2017-06-13

    Meeting climate change targets to limit global warming to 2°C requires rapid and large reductions in demand for products that most contribute to greenhouse gas (GHG) emissions. These include production of bulk materials (e.g. steel and cement), energy supply (e.g. fossil fuels) and animal source foods (particularly ruminants and their products). Effective strategies to meet these targets require transformative changes in supply as well as demand, involving changes in economic, political and legal systems at local, national and international levels, building on evidence from many disciplines. This paper outlines contributions from behavioural science in reducing demand. Grounded in dual-process models of human behaviour (involving non-conscious and conscious processes) this paper considers first why interventions aimed at changing population values towards the environment are usually insufficient or unnecessary for reducing demand although they may be important in increasing public acceptability of policies that could reduce demand. It then outlines two sets of evidence from behavioural science towards effective systems-based strategies, to identify interventions likely to be effective at: (i) reducing demand for products that contribute most to GHG emissions, mainly targeting non-conscious processes and (ii) increasing public acceptability for policy changes to enable these interventions, targeting conscious processes.This article is part of the themed issue 'Material demand reduction'. © 2017 The Authors.

  8. Towards environmentally sustainable human behaviour: targeting non-conscious and conscious processes for effective and acceptable policies

    Science.gov (United States)

    Marteau, Theresa M.

    2017-05-01

    Meeting climate change targets to limit global warming to 2°C requires rapid and large reductions in demand for products that most contribute to greenhouse gas (GHG) emissions. These include production of bulk materials (e.g. steel and cement), energy supply (e.g. fossil fuels) and animal source foods (particularly ruminants and their products). Effective strategies to meet these targets require transformative changes in supply as well as demand, involving changes in economic, political and legal systems at local, national and international levels, building on evidence from many disciplines. This paper outlines contributions from behavioural science in reducing demand. Grounded in dual-process models of human behaviour (involving non-conscious and conscious processes) this paper considers first why interventions aimed at changing population values towards the environment are usually insufficient or unnecessary for reducing demand although they may be important in increasing public acceptability of policies that could reduce demand. It then outlines two sets of evidence from behavioural science towards effective systems-based strategies, to identify interventions likely to be effective at: (i) reducing demand for products that contribute most to GHG emissions, mainly targeting non-conscious processes and (ii) increasing public acceptability for policy changes to enable these interventions, targeting conscious processes. This article is part of the themed issue 'Material demand reduction'.

  9. Processes of globalization, economic policy and the role of state in raw materials and energy complex

    Directory of Open Access Journals (Sweden)

    Vladimír Vodzinský

    2009-09-01

    Full Text Available Authors dedicate this article to impacts of constrains in paradigm of potentials forming our society.As entire societies are assembled in certain pattern, this article is dedicated to reasoning why economical growth builton influence and a use of knowledge of the reasons would accelerate consumer orientation of reproduction cycle on the levelof ownership.Both of these, causes and reasons, result in aggravation of social order and ecological crises.End products of globalization and concomitant state economic policies do not lead to crisis solution nor do they lead to effectivedisappearance of their consequences.

  10. REDIdb: an upgraded bioinformatics resource for organellar RNA editing sites.

    Science.gov (United States)

    Picardi, Ernesto; Regina, Teresa M R; Verbitskiy, Daniil; Brennicke, Axel; Quagliariello, Carla

    2011-03-01

    RNA editing is a post-transcriptional molecular process whereby the information in a genetic message is modified from that in the corresponding DNA template by means of nucleotide substitutions, insertions and/or deletions. It occurs mostly in organelles by clade-specific diverse and unrelated biochemical mechanisms. RNA editing events have been annotated in primary databases as GenBank and at more sophisticated level in the specialized databases REDIdb, dbRES and EdRNA. At present, REDIdb is the only freely available database that focuses on the organellar RNA editing process and annotates each editing modification in its biological context. Here we present an updated and upgraded release of REDIdb with a web-interface refurbished with graphical and computational facilities that improve RNA editing investigations. Details of the REDIdb features and novelties are illustrated and compared to other RNA editing databases. REDIdb is freely queried at http://biologia.unical.it/py_script/REDIdb/. Copyright © 2010 Elsevier B.V. and Mitochondria Research Society. All rights reserved.

  11. Genome Editing: A New Approach to Human Therapeutics.

    Science.gov (United States)

    Porteus, Matthew

    2016-01-01

    The ability to manipulate the genome with precise spatial and nucleotide resolution (genome editing) has been a powerful research tool. In the past decade, the tools and expertise for using genome editing in human somatic cells and pluripotent cells have increased to such an extent that the approach is now being developed widely as a strategy to treat human disease. The fundamental process depends on creating a site-specific DNA double-strand break (DSB) in the genome and then allowing the cell's endogenous DSB repair machinery to fix the break such that precise nucleotide changes are made to the DNA sequence. With the development and discovery of several different nuclease platforms and increasing knowledge of the parameters affecting different genome editing outcomes, genome editing frequencies now reach therapeutic relevance for a wide variety of diseases. Moreover, there is a series of complementary approaches to assessing the safety and toxicity of any genome editing process, irrespective of the underlying nuclease used. Finally, the development of genome editing has raised the issue of whether it should be used to engineer the human germline. Although such an approach could clearly prevent the birth of people with devastating and destructive genetic diseases, questions remain about whether human society is morally responsible enough to use this tool.

  12. The ethics of interrogation and the American Psychological Association: a critique of policy and process.

    Science.gov (United States)

    Olson, Brad; Soldz, Stephen; Davis, Martha

    2008-01-29

    The Psychological Ethics and National Security (PENS) task force was assembled by the American Psychological Association (APA) to guide policy on the role of psychologists in interrogations at foreign detention centers for the purpose of U.S. national security. The task force met briefly in 2005, and its report was quickly accepted by the APA Board of Directors and deemed consistent with the APA Ethics Code by the APA Ethics Committee. This rapid acceptance was unusual for a number of reasons but primarily because of the APA's long-standing tradition of taking great care in developing ethical policies that protected anyone who might be impacted by the work of psychologists. Many psychological and non-governmental organizations (NGOs), as well as reputable journalists, believed the risk of harm associated with psychologist participation in interrogations at these detention centers was not adequately addressed by the report. The present critique analyzes the assumptions of the PENS report and its interpretations of the APA Ethics Code. We demonstrate that it presents only one (and not particularly representative) side of a complex set of ethical issues. We conclude with a discussion of more appropriate psychological contributions to national security and world peace that better respect and preserve human rights.

  13. The ethics of interrogation and the American Psychological Association: A critique of policy and process

    Directory of Open Access Journals (Sweden)

    Davis Martha

    2008-01-01

    Full Text Available Abstract The Psychological Ethics and National Security (PENS task force was assembled by the American Psychological Association (APA to guide policy on the role of psychologists in interrogations at foreign detention centers for the purpose of U.S. national security. The task force met briefly in 2005, and its report was quickly accepted by the APA Board of Directors and deemed consistent with the APA Ethics Code by the APA Ethics Committee. This rapid acceptance was unusual for a number of reasons but primarily because of the APA's long-standing tradition of taking great care in developing ethical policies that protected anyone who might be impacted by the work of psychologists. Many psychological and non-governmental organizations (NGOs, as well as reputable journalists, believed the risk of harm associated with psychologist participation in interrogations at these detention centers was not adequately addressed by the report. The present critique analyzes the assumptions of the PENS report and its interpretations of the APA Ethics Code. We demonstrate that it presents only one (and not particularly representative side of a complex set of ethical issues. We conclude with a discussion of more appropriate psychological contributions to national security and world peace that better respect and preserve human rights.

  14. The impact of continuity editing in narrative film on event segmentation.

    Science.gov (United States)

    Magliano, Joseph P; Zacks, Jeffrey M

    2011-01-01

    Filmmakers use continuity editing to engender a sense of situational continuity or discontinuity at editing boundaries. The goal of this study was to assess the impact of continuity editing on how people perceive the structure of events in a narrative film and to identify brain networks that are associated with the processing of different types of continuity editing boundaries. Participants viewed a commercially produced film and segmented it into meaningful events, while brain activity was recorded with functional magnetic resonance imaging (MRI). We identified three degrees of continuity that can occur at editing locations: edits that are continuous in space, time, and action; edits that are discontinuous in space or time but continuous in action; and edits that are discontinuous in action as well as space or time. Discontinuities in action had the biggest impact on behavioral event segmentation, and discontinuities in space and time had minor effects. Edits were associated with large transient increases in early visual areas. Spatial-temporal changes and action changes produced strikingly different patterns of transient change, and they provided evidence that specialized mechanisms in higher order perceptual processing regions are engaged to maintain continuity of action in the face of spatiotemporal discontinuities. These results suggest that commercial film editing is shaped to support the comprehension of meaningful events that bridge breaks in low-level visual continuity, and even breaks in continuity of spatial and temporal location. Copyright © 2011 Cognitive Science Society, Inc.

  15. Implementation of a Positive Youth Development Program in a Chinese Context: The Role of Policy, Program, People, Process, and Place

    Directory of Open Access Journals (Sweden)

    Daniel T. L. Shek

    2008-01-01

    Full Text Available In this paper, a case study is presented based on one school, conducted to examine the factors that influenced the process and quality of implementation of the Tier 1 Program of the Project P.A.T.H.S. Through interviews with the school contact person and focus group interviews with the instructors, an integration of the findings showed that several factors related to the program, people, process, policy, and place (5 “P”s facilitated the implementation process of the Tier 1 Program in the school. Obstacles and difficulties with reference to the 5 “P”s that affected the quality of implementation were also identified. Overall, the quality of program implementation in the school was good, and the program was well received by the program implementers. Implications of the present findings for future program implementation with reference to school administrative arrangements and implementation issues are discussed.

  16. Multi-Level Policy Dialogues, Processes, and Actions: Challenges and Opportunities for National REDD+ Safeguards Measurement, Reporting, and Verification (MRV

    Directory of Open Access Journals (Sweden)

    Pamela Jagger

    2014-09-01

    Full Text Available REDD+ social safeguards have gained increasing attention in numerous forums. This paper reviews the evolution of multi-level policy dialogues, processes, and actions related to REDD+ social safeguards (e.g., Cancun Safeguards 1–5 among policy makers, civil society organizations, and within the media in Brazil, Indonesia and Tanzania, three countries with well advanced REDD+ programs. We find that progress on core aspects of social safeguards is uneven across the three countries. Brazil is by far the most advanced having drafted a REDD+ social safeguards policy. Both Brazil and Indonesia have benefited from progress made by strong sub-national entities in the operationalization of REDD+ safeguards including free prior and informed consent (FPIC, participation, and benefit sharing. Tanzania has weakly articulated how social safeguards will be operationalized and has a more top-down approach. We conclude that in all three countries, measuring, reporting and verifying progress on social safeguards is likely to be a complex issue. Stakeholders with vested interests in REDD+ social safeguards operate in polycentric rather than nested systems, suggesting that aggregation of information from local to national-scale will be a challenge. However, polycentric systems are also likely to support more transparent and comprehensive safeguards systems. Clear direction from the international community and financing for REDD+ safeguard MRV is essential if REDD+ social safeguards are to be meaningfully integrated into forest-based climate mitigation strategies.

  17. European environmental policy: The pioneers

    DEFF Research Database (Denmark)

    Andersen and Liefferink's edited volume takes a different approach to comparative environmental policy studies. It looks at how domestic environmental policies and activities In six specific countries (Sweden, Austria, Finland, Germany, The Netherlands, Denmark and Norway) have affected...... to enable a regional agreement to be reached, and at other times they need to use regional policy-making as a way to put pressure on domestic constituencies....

  18. The Invisible Hand or What Makes the Bureaucracy Indispensable? A Short Theoretical Inquiry Into the Bureaucracy's Role in the Policy Making Process

    Directory of Open Access Journals (Sweden)

    Cristina HARUŢA

    2010-02-01

    Full Text Available In the study of public bureaucracy, an intrinsic preoccupation arises concerning the balance of policy making authority between politicians and bureaucrats. In this paper we attempt to show from a theoretical point of view that bureaucracies enjoy some degree of discretion over policy making via implementation, rulemaking and enforcement activities. According to many authors it appears that the bureaucrats are entitled as well to play the role of both partners and contributors in the public policy formulation process, even if sometimes their policy preferences do not overlap all the times with the preferences of their elected overseers.

  19. Environmental policy in Norway: emission quotas to the processing industries, taxation of the oil companies

    International Nuclear Information System (INIS)

    Tjernshaugen, Andreas

    2002-01-01

    In a white paper on the climate policy, the Norwegian Government proposes a variety of political instruments. In the years 2005 to 2007, the Government will give priority to a quota system for the industrial sectors that are currently exempt from the CO 2 tax. At the same time, the tax on oil- and gas extraction and on traffic will be continued. In addition, a series of measures are evaluated against specific emission sources such as waste management and oil heating. For the years 2008 to 2012, which is the period of commitment under the Kyoto protocol, the CO 2 will be replaced by a broad quota system that will apply to all sources that can be technically included

  20. The International System in the 21st Century: Considering the U.S. Role. Third Edition. Teacher Resource Book [and Student Text]. Public Policy Debate in the Classroom. Choices for the 21st Century.

    Science.gov (United States)

    Fox, Sarah Cleveland

    Although the attacks of September 11, 2001, present new challenges and priorities for U.S. policy, it is uncertain what direction international relations will take. China's growth and power, Russia's political and economic problems, resentment and corruption in Russia, and global warming effect policymaking. While the war on terrorism may be a…

  1. Emerging technologies planning guide, 1993 edition

    Energy Technology Data Exchange (ETDEWEB)

    1992-11-01

    Information system technology enhancements during the next five years are expected to provide some of the most significant individual and organization work improvements ever made in the office environment. This guide is an aid to planning these technologies and assessing their roles in improving the effectiveness of Headquarters programs. Their implementation will cost-effectively support Departmental operations and the National Energy Strategy. At the hear of this process is an understanding of the relationship which exists between technology introduction and the planning, budgeting and acquisition process. The 1993 edition of this guide covers the 1993--1997 time frame.

  2. [Preface for genome editing special issue].

    Science.gov (United States)

    Gu, Feng; Gao, Caixia

    2017-10-25

    Genome editing technology, as an innovative biotechnology, has been widely used for editing the genome from model organisms, animals, plants and microbes. CRISPR/Cas9-based genome editing technology shows its great value and potential in the dissection of functional genomics, improved breeding and genetic disease treatment. In the present special issue, the principle and application of genome editing techniques has been summarized. The advantages and disadvantages of the current genome editing technology and future prospects would also be highlighted.

  3. Marine botany. Second edition

    Energy Technology Data Exchange (ETDEWEB)

    Dawes, C.J. [Univ. of South Florida, Tampa, FL (United States)

    1998-12-01

    Marine plants are a diverse group that include unicellular algae, seaweeds, seagrasses, salt marshes, and mangrove forests. They carry out a variety of ecological functions and serve as the primary producers in coastal wetlands and oceanic waters. The theme that connects such a wide variety of plants is their ecology, which was also emphasized in the 1981 edition. The goal of this revision is to present taxonomic, physiological, chemical, and ecological aspects of marine plants, their adaptations, and how abiotic and biotic factors interact in their communities. The data are presented in a concise, comparative manner in order to identify similarities and differences between communities such as salt marsh and mangroves or subtidal seaweeds and seagrasses. To accomplish this, the text is organized into five chapters that introduce the marine habitats, consider abiotic and biotic factors, and anthropogenic influences on the communities followed by seven chapters that deal with microalgae, seaweeds, salt marshes, mangroves, seagrasses, and coral reefs. Two appendixes are included; one presents simple field techniques and the other is a summary of seaweed uses.

  4. Genome editing in cardiovascular diseases.

    Science.gov (United States)

    Strong, Alanna; Musunuru, Kiran

    2017-01-01

    Genome-editing tools, which include zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated 9 (Cas9) systems, have emerged as an invaluable technology to achieve somatic and germline genomic manipulation in cells and model organisms for multiple applications, including the creation of knockout alleles, introducing desired mutations into genomic DNA, and inserting novel transgenes. Genome editing is being rapidly adopted into all fields of biomedical research, including the cardiovascular field, where it has facilitated a greater understanding of lipid metabolism, electrophysiology, cardiomyopathies, and other cardiovascular disorders, has helped to create a wider variety of cellular and animal models, and has opened the door to a new class of therapies. In this Review, we discuss the applications of genome-editing technology throughout cardiovascular disease research and the prospect of in vivo genome-editing therapies in the future. We also describe some of the existing limitations of genome-editing tools that will need to be addressed if cardiovascular genome editing is to achieve its full scientific and therapeutic potential.

  5. The Formation of Accounting Policies for Processing Enterprises in the Context of Adaptation of National Regulations to the International Standards of Accounting and Reporting

    Directory of Open Access Journals (Sweden)

    Rozheliuk Viktoriia M.

    2017-04-01

    Full Text Available The article defines principles for preparation of accounting policies using both domestic and foreign experience, generalizes scientific and theoretical approaches, and improves the wordings of the concept of «accounting policy». The feasibility of conducting a preliminary assessment of efficiency of organizational activities through the use of the criteria generalized in the accounting policy has been substantiated, the legal and regulatory levels have been highlighted, taking into consideration the existing legislation. The procedure for determining the accounting policy parameters and directions has been disclosed, requirements to the formation of accounting policy have been defined, influencing of factors on its formation in market conditions has been researched. Recommendations for the main sections of the accounting policy order in the processing enterprise have been formulated, a list of parts of the accounting policy order has been determined, taking into consideration the organization and technology of the working process of processing enterprises in the circumstances of market economy. A comparison of international and national regulations on the formation of accounting policies for the market-based enterprises has been carried out.

  6. Genome editing of crops: A renewed opportunity for food security.

    Science.gov (United States)

    Georges, Fawzy; Ray, Heather

    2017-01-02

    Genome editing of crop plants is a rapidly advancing technology whereby targeted mutations can be introduced into a plant genome in a highly specific manner and with great precision. For the most part, the technology does not incorporate transgenic modifications and is far superior to conventional chemical mutagenesis. In this study we bring into focus some of the underlying differences between the 3 existing technologies: classical plant breeding, genetic modification and genome editing. We discuss some of the main achievements from each area and highlight their common characteristics and individual limitations, while emphasizing the unique capabilities of genome editing. We subsequently examine the possible regulatory mechanisms which governments may be inclined to use in assessing the status of genome edited products. If assessed on the basis of their phenotype rather than the process by which they are obtained, these products will be categorized as equivalent to those produced by classical mutagenesis. This would mean that genome edited products will not be subject to the restrictions imposed on genetically modified products, except in some cases where the mutation involves a large sequence insertion into the genome. We conclude by examining the potential of societal acceptance of genome editing technology, reinforced by a scientific perspective on promoting such acceptance.

  7. A comparison of the first and second editions of the Dictionary of Literary Slovene

    Directory of Open Access Journals (Sweden)

    Simon Krek

    2014-12-01

    Full Text Available The paper investigates the differences between the first and second editions of the Dictionary of Literary Slovene (SSKJ. The analysis is two-fold: first, a detailed comparison of headword lists of both editions is conducted, followed by the comparison of 2,500 entries from both editions, consisting of a hundred entries for each letter. The analysis shows that the spelling and pronunciation changes to the entries in the second edition were made without the approval of any relevant language authority. Also, the changes introduced are random and inconsistent, and are affecting the consistency of lexicographic description of the first edition, especially on the grammatical level. Furthermore, the editorial decision to make identifying the source of lexicographic information (i.e. the first edition of SSKJ or the Dictionary of New Words of the Slovenian language impossible, raises doubts about lexicographic credibility of the second edition as a description of contemporary Slovene. From the lexicographic perspective, it would have been more appropriate to leave the first edition unchanged and the Dictionary of New Words of the Slovenian language as a separate publication. In addition, the second edition of SSKJ is not freely available online, and neither of the editions is freely available in the form of a dictionary database for natural language processing and other uses.

  8. The policy process in a petro-state. An analysis of PDVSA's (Petroleos de Venezuela SA's) internationalisation strategy

    Energy Technology Data Exchange (ETDEWEB)

    Baena, C.E. [Instituto de Estudios Superiores de Administracion, Caracas (Venezuela)

    1999-07-01

    Venezuela offers a unique case and fertile ground for the study of oil policy-making processes. In the specialised literature very little attention has been paid to the nature and operations of multinationals from developing countries. By analysing Petroleos de Venezuela SA's (PDVSA's) internationalisation policy, this unique book explores the difficulties encountered by a major state oil enterprise in its efforts to grow beyond national borders. This informative study focuses on the impact of democratic bargaining on the process of oil policy-making in Venezuela, stressing the constraints posed by politics on PDVSA's efforts to expand its foreign operations. (author)

  9. To edit or not to edit: regulation of ADAR editing specificity and efficiency.

    Science.gov (United States)

    Deffit, Sarah N; Hundley, Heather A

    2016-01-01

    Hundreds to millions of adenosine (A)-to-inosine (I) modifications are present in eukaryotic transcriptomes and play an essential role in the creation of proteomic and phenotypic diversity. As adenosine and inosine have different base-pairing properties, the functional consequences of these modifications or 'edits' include altering coding potential, splicing, and miRNA-mediated gene silencing of transcripts. However, rather than serving as a static control of gene expression, A-to-I editing provides a means to dynamically rewire the genetic code during development and in a cell-type specific manner. Interestingly, during normal development, in specific cells, and in both neuropathological diseases and cancers, the extent of RNA editing does not directly correlate with levels of the substrate mRNA or the adenosine deaminase that act on RNA (ADAR) editing enzymes, implying that cellular factors are required for spatiotemporal regulation of A-to-I editing. The factors that affect the specificity and extent of ADAR activity have been thoroughly dissected in vitro. Yet, we still lack a complete understanding of how specific ADAR family members can selectively deaminate certain adenosines while others cannot. Additionally, in the cellular environment, ADAR specificity and editing efficiency is likely to be influenced by cellular factors, which is currently an area of intense investigation. Data from many groups have suggested two main mechanisms for controlling A-to-I editing in the cell: (1) regulating ADAR accessibility to target RNAs and (2) protein-protein interactions that directly alter ADAR enzymatic activity. Recent studies suggest cis- and trans-acting RNA elements, heterodimerization and RNA-binding proteins play important roles in regulating RNA editing levels in vivo. WIREs RNA 2016, 7:113-127. doi: 10.1002/wrna.1319. © 2015 Wiley Periodicals, Inc.

  10. Social values and health policy: a new international research programme.

    Science.gov (United States)

    Littlejohns, Peter; Weale, Albert; Chalkidou, Kalipso; Faden, Ruth; Teerawattananon, Yot

    2012-01-01

    This editorial aims to outline the context of healthcare priority-setting, and summarise each of the other ten papers in this special edition. It introduces a new multidisciplinary research programme drawing on ethics, philosophy, health economics, political science and health technology assessment, out of which the papers in this edition have arisen. Key normative concepts are introduced and policy and research context provided to frame subsequent papers in the edition. Common challenges of health priority-setting are faced by many countries across the world, and a range of social value judgments is in play as resource allocation decisions are made. Although the challenges faced by different countries are in many ways similar, the way in which social values affect the processes and content of priority-setting decisions means that those challenges are resolved very differently in a variety of social, political, cultural and institutional settings, as subsequent papers in this edition demonstrate. How social values affect decision making in this way is the subject of a new multi-disciplinary research programme. Technical analyses of health priority setting are commonplace, but approaching the issues from the perspective of social values and conducting comparative analyses across countries with very different cultural, social and institutional contexts provides the content for a new research agenda.

  11. Replacement policy in a system under shocks following a Markovian arrival process

    Energy Technology Data Exchange (ETDEWEB)

    Montoro-Cazorla, Delia [Department of Statistics and Operational Research, University of Jaen (Spain); Perez-Ocon, Rafael [Department of Statistics and Operational Research, University of Granada, Granada (Spain)], E-mail: rperezo@ugr.es; Carmen Segovia, Maria del [Departamento de Estadistica e I.O., University of Granada, Granada (Spain)

    2009-02-15

    We present a system subject to shocks that arrive following a Markovian arrival process. The system is minimally repaired. It is replaced when a certain number of shocks arrive. A general model where the replacements are governed by a discrete phase-type distribution is studied. For this system, the Markov process governing the system is constructed, and the interarrival times between replacements and the number of replacements are calculated. A special case of this system is when it can stand a prefixed number of shocks. For this new system, the same performance measures are calculated. The systems are considered in transient and stationary regime.

  12. Loss of matK RNA editing in seed plant chloroplasts

    Directory of Open Access Journals (Sweden)

    Maier Uwe G

    2009-08-01

    Full Text Available Abstract Background RNA editing in chloroplasts of angiosperms proceeds by C-to-U conversions at specific sites. Nuclear-encoded factors are required for the recognition of cis-elements located immediately upstream of editing sites. The ensemble of editing sites in a chloroplast genome differs widely between species, and editing sites are thought to evolve rapidly. However, large-scale analyses of the evolution of individual editing sites have not yet been undertaken. Results Here, we analyzed the evolution of two chloroplast editing sites, matK-2 and matK-3, for which DNA sequences from thousands of angiosperm species are available. Both sites are found in most major taxa, including deep-branching families such as the nymphaeaceae. However, 36 isolated taxa scattered across the entire tree lack a C at one of the two matK editing sites. Tests of several exemplary species from this in silico analysis of matK processing unexpectedly revealed that one of the two sites remain unedited in almost half of all species examined. A comparison of sequences between editors and non-editors showed that specific nucleotides co-evolve with the C at the matK editing sites, suggesting that these nucleotides are critical for editing-site recognition. Conclusion (i Both matK editing sites were present in the common ancestor of all angiosperms and have been independently lost multiple times during angiosperm evolution. (ii The editing activities corresponding to matK-2 and matK-3 are unstable. (iii A small number of third-codon positions in the vicinity of editing sites are selectively constrained independent of the presence of the editing site, most likely because of interacting RNA-binding proteins.

  13. Loss of matK RNA editing in seed plant chloroplasts

    Science.gov (United States)

    Tillich, Michael; Le Sy, Vinh; Schulerowitz, Katrin; von Haeseler, Arndt; Maier, Uwe G; Schmitz-Linneweber, Christian

    2009-01-01

    Background RNA editing in chloroplasts of angiosperms proceeds by C-to-U conversions at specific sites. Nuclear-encoded factors are required for the recognition of cis-elements located immediately upstream of editing sites. The ensemble of editing sites in a chloroplast genome differs widely between species, and editing sites are thought to evolve rapidly. However, large-scale analyses of the evolution of individual editing sites have not yet been undertaken. Results Here, we analyzed the evolution of two chloroplast editing sites, matK-2 and matK-3, for which DNA sequences from thousands of angiosperm species are available. Both sites are found in most major taxa, including deep-branching families such as the nymphaeaceae. However, 36 isolated taxa scattered across the entire tree lack a C at one of the two matK editing sites. Tests of several exemplary species from this in silico analysis of matK processing unexpectedly revealed that one of the two sites remain unedited in almost half of all species examined. A comparison of sequences between editors and non-editors showed that specific nucleotides co-evolve with the C at the matK editing sites, suggesting that these nucleotides are critical for editing-site recognition. Conclusion (i) Both matK editing sites were present in the common ancestor of all angiosperms and have been independently lost multiple times during angiosperm evolution. (ii) The editing activities corresponding to matK-2 and matK-3 are unstable. (iii) A small number of third-codon positions in the vicinity of editing sites are selectively constrained independent of the presence of the editing site, most likely because of interacting RNA-binding proteins. PMID:19678945

  14. The Impact of Institutional Culture, Policy and Process on Student Engagement in University Decision-Making

    Science.gov (United States)

    Carey, Philip

    2018-01-01

    There is a strong focus on the importance of student engagement in higher education, with increasing attention on how students can participate in their university's decision-making processes. Yet, although the concept appears to be almost universally accepted, it is rarely problematised. This has led some commentators to conclude that student…

  15. 76 FR 60941 - Policy Regarding Submittal of Amendments for Processing of Equivalent Feed at Licensed Uranium...

    Science.gov (United States)

    2011-09-30

    ... feed as material other than natural uranium ores. Alternate feed can, therefore, be certain wastes... waste would be considered as 11e.(2) byproduct material. To constitute equivalent feed, resin must be... facilities, the wastes associated with processing equivalent feed (i.e., unloaded resin) are considered...

  16. Tightening the Purchasing Process: Superintendents Get More Involved in Buying Policies

    Science.gov (United States)

    Rivero, Victor

    2009-01-01

    Over the last 18 months, school district purchasing offices across the country have been tightening the reins like never before while more top-level administrators get involved in the budget process. "When the economy really hit the skids, states got hit hard, so a lot of school districts were forced to make severe budget cuts," says John Musso,…

  17. Ecological modernization and environmental policy reform in Thailand: the case of food processing SMEs

    NARCIS (Netherlands)

    Wattanapinyo, A.; Mol, A.P.J.

    2013-01-01

    To mitigate environmental pollution from a rapidly expanding Thai food processing industry, different options and technologies can be identifi ed. However, actually implementing these environmental improvements within small and medium-sized agro-food companies requires governing efforts of a variety

  18. The Bologna Process Policy Implementation in Russia and Ukraine: Similarities and Differences

    Science.gov (United States)

    Luchinskaya, Daria; Ovchynnikova, Olena

    2011-01-01

    The recent establishment of the European Higher Education Area and the ongoing monitoring carried out by the Bologna Follow-up Group raises the question: to what extent have the objectives of the Bologna Process been implemented in the varied higher education systems of the 47 signatory states, including the former Soviet Union states? This…

  19. U.S. Budgeting for the United Nations: Process, Policy, and Problems

    Science.gov (United States)

    2009-06-01

    that concluded WWII; Chapter XVIII deal with the method for amending the Charter; and Chapter XIX describes the time line and process for Charter...In the last few years there have been reports of crimes by UN personnel, including rape and forced prostitution of women and young girls (Schaefer

  20. Re-approaching social development: a field of action between social life and policy processes

    NARCIS (Netherlands)

    Arce, A.M.G.

    2003-01-01

    This article reflects on contemporary social development, and suggests that we need to initiate a process of thinking about a post neo-liberal development agenda. As a step in this direction, it is suggested we need to re-approach the social as a conceptual category in order to consider social

  1. Community Psychology as a Process of Citizen Participation in Health Policy Comment on "The Rise of Post-truth Populism in Pluralist Liberal Democracies: Challenges for Health Policy".

    Science.gov (United States)

    Taggart, Danny

    2017-06-25

    This brief commentary discusses a recent paper by Speed and Mannion that explores "The Rise of post truth populism in liberal democracies: challenges for health policy." It considers their assertion that through meaningful democratic engagement in health policy, some of the risks brought about by an exclusionary populist politics can be mediated. With an overview of what participation means in modern healthcare policy and implementation, the field of community psychology is presented as one way to engage marginalized groups at risk of exploitation or exclusion by nativist populist policy. © 2018 The Author(s); Published by Kerman University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

  2. The development of new environmental policies and processes in response to a crisis: the case of the multiple barrier approach for safe drinking water

    International Nuclear Information System (INIS)

    Plummer, Ryan; Velaniskis, Jonas; Grosbois, Danuta de; Kreutzwiser, Reid D.; Loe, Rob de

    2010-01-01

    While new environmental policies and procedures often are developed incrementally, they can also result from crises or other significant events. In situations where policies and procedures are introduced in response to a crisis, questions about the strengths and weaknesses of existing mechanisms, and the extent to which they can be used to address concerns, may be ignored. This paper explores the complexities of introducing new policies and processes where planning systems and procedures already exist. Drinking water source protection policies that are being developed in response to the tragic events in Walkerton, Ontario, Canada serve as the context for the inquiry. Three case study watersheds were selected to reflect the diversity of municipal jurisdictions and water supply systems in Ontario. A content analysis was undertaken on regulatory and non-regulatory policy documents to determine the extent to which they addressed elements of the multi-barrier approach for drinking water safety. Findings from the research reveal considerable evidence of the multi-barrier approach in the policy and guiding documents analyzed. Policy development in response to a crisis can advance progress on the issue of drinking water safety and coincide with emerging governance strategies. Policy effectiveness may be enhanced by considering existing policies as well as contextual and jurisdictional differences.

  3. Scalable approximate policies for Markov decision process models of hospital elective admissions.

    Science.gov (United States)

    Zhu, George; Lizotte, Dan; Hoey, Jesse

    2014-05-01

    To demonstrate the feasibility of using stochastic simulation methods for the solution of a large-scale Markov decision process model of on-line patient admissions scheduling. The problem of admissions scheduling is modeled as a Markov decision process in which the states represent numbers of patients using each of a number of resources. We investigate current state-of-the-art real time planning methods to compute solutions to this Markov decision process. Due to the complexity of the model, traditional model-based planners are limited in scalability since they require an explicit enumeration of the model dynamics. To overcome this challenge, we apply sample-based planners along with efficient simulation techniques that given an initial start state, generate an action on-demand while avoiding portions of the model that are irrelevant to the start state. We also propose a novel variant of a popular sample-based planner that is particularly well suited to the elective admissions problem. Results show that the stochastic simulation methods allow for the problem size to be scaled by a factor of almost 10 in the action space, and exponentially in the state space. We have demonstrated our approach on a problem with 81 actions, four specialities and four treatment patterns, and shown that we can generate solutions that are near-optimal in about 100s. Sample-based planners are a viable alternative to state-based planners for large Markov decision process models of elective admissions scheduling. Copyright © 2014 Elsevier B.V. All rights reserved.

  4. Social Media and the Policy-Making Process a Traditional Novel Interaction

    Science.gov (United States)

    2014-02-13

    in their deliberative process. 1 Introduction Social media is a new model of interaction that brings unanticipated changes to the world’s...communication strategy aimed only at a few groups and channeled only through traditional media will necessarily fall short . 31 However, according...in a Globalised World, ed. Jolyon Welsh and Daniel Fearn (London: Foreign and Commonwealth Office, 2008), 66, http://uscpublicdiplomacy.org

  5. Connectivity editing for quadrilateral meshes

    KAUST Repository

    Peng, Chihan

    2011-12-01

    We propose new connectivity editing operations for quadrilateral meshes with the unique ability to explicitly control the location, orientation, type, and number of the irregular vertices (valence not equal to four) in the mesh while preserving sharp edges. We provide theoretical analysis on what editing operations are possible and impossible and introduce three fundamental operations to move and re-orient a pair of irregular vertices. We argue that our editing operations are fundamental, because they only change the quad mesh in the smallest possible region and involve the fewest irregular vertices (i.e., two). The irregular vertex movement operations are supplemented by operations for the splitting, merging, canceling, and aligning of irregular vertices. We explain how the proposed high-level operations are realized through graph-level editing operations such as quad collapses, edge flips, and edge splits. The utility of these mesh editing operations are demonstrated by improving the connectivity of quad meshes generated from state-of-art quadrangulation techniques.

  6. Connectivity editing for quadrilateral meshes

    KAUST Repository

    Peng, Chihan

    2011-12-12

    We propose new connectivity editing operations for quadrilateral meshes with the unique ability to explicitly control the location, orientation, type, and number of the irregular vertices (valence not equal to four) in the mesh while preserving sharp edges. We provide theoretical analysis on what editing operations are possible and impossible and introduce three fundamental operations to move and re-orient a pair of irregular vertices. We argue that our editing operations are fundamental, because they only change the quad mesh in the smallest possible region and involve the fewest irregular vertices (i.e., two). The irregular vertex movement operations are supplemented by operations for the splitting, merging, canceling, and aligning of irregular vertices. We explain how the proposed highlevel operations are realized through graph-level editing operations such as quad collapses, edge flips, and edge splits. The utility of these mesh editing operations are demonstrated by improving the connectivity of quad meshes generated from state-of-art quadrangulation techniques. © 2011 ACM.

  7. [Genome editing of industrial microorganism].

    Science.gov (United States)

    Zhu, Linjiang; Li, Qi

    2015-03-01

    Genome editing is defined as highly-effective and precise modification of cellular genome in a large scale. In recent years, such genome-editing methods have been rapidly developed in the field of industrial strain improvement. The quickly-updating methods thoroughly change the old mode of inefficient genetic modification, which is "one modification, one selection marker, and one target site". Highly-effective modification mode in genome editing have been developed including simultaneous modification of multiplex genes, highly-effective insertion, replacement, and deletion of target genes in the genome scale, cut-paste of a large DNA fragment. These new tools for microbial genome editing will certainly be applied widely, and increase the efficiency of industrial strain improvement, and promote the revolution of traditional fermentation industry and rapid development of novel industrial biotechnology like production of biofuel and biomaterial. The technological principle of these genome-editing methods and their applications were summarized in this review, which can benefit engineering and construction of industrial microorganism.

  8. A multi-level analysis of the EU linking directive process: the controversial connection between EU and global climate policy

    Energy Technology Data Exchange (ETDEWEB)

    Flaam, Karoline Haegstad

    2007-10-15

    Despite initial scepticism in the EU towards the Kyoto Protocol's project mechanisms (the CDM and JI), the 'Linking Directive' was adopted in October 2004, connecting the EU emissions trading scheme with the project mechanisms. Not only was the Linking Directive settled remarkably quickly, the decision-making process also left a more liberal text, with fewer restrictions on the use of the project mechanisms, as compared to the initial directive proposal. This report examines possible explanations to this puzzle, evaluating whether Member State preferences, EU institutions or external influence from the climate regime best can contribute to understanding the process. On the basis of the analysis of written sources stemming from the decision-making process, as well as seven in-depth interviews, the report finds that Member State preferences were the main driver in the Linking Directive process. This gives support to the intergovernmentalist mantra, that Member States are the main decision-makers in the EU. It also challenges much recent research claiming that EU policy-making is increasingly being taken out of the hands of the nation-state and into supranational actors such as the Commission and the European Parliament. (author). 41 refs., figs., tabs

  9. Collaboration: a SWOT analysis of the process of conducting a review of nursing workforce policies in five European countries.

    Science.gov (United States)

    Uhrenfeldt, Lisbeth; Lakanmaa, Riitta-Liisa; Flinkman, Mervi; Basto, Marta Lima; Attree, Moira

    2014-05-01

    This paper critically reviews the literature on international collaboration and analyses the collaborative process involved in producing a nursing workforce policy analysis. Collaboration is increasingly promoted as a means of solving shared problems and achieving common goals; however, collaboration creates its own opportunities and challenges. Evidence about the collaboration process, its outcomes and critical success factors is lacking. A literature review and content analysis of data collected from six participants (from five European countries) members of the European Academy of Nursing Science Scholar Collaborative Workforce Workgroup, using a SWOT (Strengths, Weaknesses, Opportunities and Threats) analysis template. Two major factors affecting scholarly collaboration were identified: Facilitators, which incorporated personal attributes and enabling contexts/mechanisms, including individual commitment, responsibility and teamwork, facilitative supportive structures and processes. The second, Barriers, incorporated unmet needs for funding; time; communication and impeding contexts/mechanisms, including workload and insufficient support/mentorship. The literature review identified a low level of evidence on collaboration processes, outcomes, opportunities and challenges. The SWOT analysis identified critical success factors, planning strategies and resources of effective international collaboration. Collaboration is an important concept for management. Evidence-based knowledge of the critical success factors facilitating and impeding collaboration could help managers make collaboration more effective. © 2012 John Wiley & Sons Ltd.

  10. Diffusion of innovation in mental health policy adoption: what should we ask about the quality of policy and the role of stakeholders in this process? Comment on "Cross-national diffusion of mental health policy".

    Science.gov (United States)

    Lee, Lucy

    2015-03-10

    In his recent study, Gordon Shen analyses a pertinent question facing the global mental health research and practice community today; that of how and why mental health policy is or is not adopted by national governments. This study identifies becoming a World Health Organization (WHO) member nation, and being in regional proximity to countries which have adopted a mental health policy as supportive of mental health policy adoption, but no support for its hypothesis that country recipients of higher levels of aid would have adopted a mental health policy due to conditionalities imposed on aid recipients by donors. Asking further questions of each may help to understand more not only about how and why mental health policies may be adopted, but also about the relevance and quality of implementation of these policies and the role of specific actors in achieving adoption and implementation of high quality mental health policies. © 2015 by Kerman University of Medical Sciences.

  11. RNA interference analyses suggest a transcript-specific regulatory role for mitochondrial RNA-binding proteins MRP1 and MRP2 in RNA editing and other RNA processing in Trypanosoma brucei

    Czech Academy of Sciences Publication Activity Database

    Horáková, Eva; Van Den Burg, J.; Zíková, Alena; Ernst, N. L.; Stuart, K.; Benne, R.; Lukeš, Julius

    2005-01-01

    Roč. 280, č. 4 (2005), s. 2429-2438 ISSN 0021-9258 R&D Projects: GA AV ČR IAA6022903 Institutional research plan: CEZ:AV0Z60220518 Keywords : Trypanosoma brucei * RNA editing * interference RNA Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 5.854, year: 2005

  12. RNA interference analyses suggest a transcript-specific regulatory role for mitochondrial RNA-binding proteins MRP1 and MRP2 in RNA editing and other RNA processing in Trypanosoma brucei

    NARCIS (Netherlands)

    Vondrusková, Eva; van den Burg, Janny; Zíková, Alena; Ernst, Nancy Lewis; Stuart, Kenneth; Benne, Rob; Lukes, Julius

    2005-01-01

    Mitochondrial RNA-binding proteins MRP1 and MRP2 occur in a heteromeric complex that appears to play a role in U-insertion/deletion editing in trypanosomes. Reduction in the levels of MRP1 (gBP21) and/or MRP2 (gBP25) mRNA by RNA interference in procyclic Trypanosoma brucei resulted in severe growth

  13. The European Union renewable directive: The policy-making process and the stakeholders positions

    Energy Technology Data Exchange (ETDEWEB)

    Gullberg, Anne Therese

    2011-07-01

    This working paper focuses on the proposal for a renewable energy directive in the European Union (EU), which main aim is to increase the share of renewable energy sources in EU energy consumption from 8.5 to 20 per cent by 2020. It accounts for the legislative process, from the drafting and consultation stage to the final directive was formally adopted in April 2009, and in particular the proposal of binding interim targets and financial penalty. The formal proposals as well as the stakeholders positions on this issue are examined.(auth)

  14. Boneless Pose Editing and Animation

    DEFF Research Database (Denmark)

    Bærentzen, Jakob Andreas; Hansen, Kristian Evers; Erleben, Kenny

    2007-01-01

    In this paper, we propose a pose editing and animation method for triangulated surfaces based on a user controlled partitioning of the model into deformable parts and rigid parts which are denoted handles. In our pose editing system, the user can sculpt a set of poses simply by transforming...... the handles for each pose. Using Laplacian editing, the deformable parts are deformed to match the handles. In our animation system the user can constrain one or several handles in order to define a new pose. New poses are interpolated from the examples poses, by solving a small non-linear optimization...... problem in order to obtain the interpolation weights. While the system can be used simply for building poses, it is also an animation system. The user can specify a path for a given constraint and the model is animated correspondingly....

  15. Editörden

    Directory of Open Access Journals (Sweden)

    Nadir Arıcan

    2007-04-01

    Full Text Available Değerli Adli Bilimci’ler, Dergimizin ilk baskısının yapıldığı 1996 yılından 2006 yılı sonuna kadar 11 ciltten oluşan dizisini ara vermeden kesintisiz olarak yayınlanma başarısını gösteren Adli Tıp Bülteni Yayın Kurulu adına saygı ile selamlıyoruz. Dergimizin 12. cildinin ilk sayısı, yayın kurulundaki görev değişikliği ile elinize ulaşıyor. “Adli Tıp Bülteni”ni tüm olumsuz koşullara karşın, siz alana emek veren adli bilimcilerin de büyük desteği ile yayın hayatım başarı ile sürdürdü. Bu başarıda başta editörlerimiz sayın Prof. Dr. Serpil Salaçin ve sayın Prof. Dr. Şebnem Korur Fincancı ile yayın kurulunda görev almış meslektaşlarımıza teşekkür ediyor ve desteklerinin artarak devam edeceğini ümit ediyoruz. Adli Tıp Bülteni, ilk editörü sayın Prof. Dr. Serpil Salaçin’in bültenin 1. sayısında belirttiği amaca uygun olarak, her geçen gün daha da güçlenerek yayın hayatını sürdürmektedir. Yayın akışında zaman zaman kesintiler olsa da, amacı doğrultusunda “alanındaki bilgi akışını sağlama ve bilimsel gelişmelerin önemli bir parçası olma özelliğini” Adli Tıp Uzmanları Derneği’nin resmi bilimsel yayın organı kimliği ile devam ettirmektedir. Hedefleri doğrultusunda uluslararası indekslerce taranan bir dergi olma yolunda ilk adımını atan dergimizin bu alandaki çalışmaları sayın Prof. Dr. Şebnem Korur Fincancı tarafından yürütülmektedir. Görevini genç meslektaşına devretmiş olsa da alanımızdaki uluslar arası deneyimi ile Adli Tıp Bülteni’ni çok farklı noktalara taşıyacağı inancındayım. Bu alanda yapacağı katkılardan dolayı sayın hocama biz kez daha teşekkür etmek istiyorum. Bundan böyle Adli Tıp Bülteni’ne yayınlanmak üzere gönderdiğiniz çalışmalarınızın değerlendirmesini daha hızlı yapabilmek ve baskı aşamasına getirmek amacı ile iletişimi elektronik ortamda yapmaya

  16. Making Space for New Voices: The Politics of Editing in South Africa ...

    African Journals Online (AJOL)

    This article looks at the dilemmas and challenges of editing in the very specific milieu of contemporary South Africa, where historically sidelined voices are just beginning to find their literary presence, and the editing process often involves a certain amount of enabling. The editor's role is to walk the delicate tension between ...

  17. The Digital Critical Edition of Fragments: Theoretical Problems and Technical Solution

    OpenAIRE

    Romanello, Matteo

    2011-01-01

    The process of creating a digital critical edition of fragmentary texts is also a valuable opportunity to look at the nature of such texts under a new light. This paper contains some reflections about how the nature of fragments can be more appropriately represented in a digital critical edition and what challenges this task poses

  18. Multiplex gene editing by CRISPR-Cpf1 using a single crRNA array

    NARCIS (Netherlands)

    Zetsche, Bernd; Heidenreich, Matthias; Mohanraju, Prarthana; Fedorova, Iana; Kneppers, Jeroen; Degennaro, Ellen M.; Winblad, Nerges; Choudhury, Sourav R.; Abudayyeh, Omar O.; Wu, Wen Y.; Oost, van der John

    2017-01-01

    Targeting of multiple genomic loci with Cas9 is limited by the need for multiple or large expression constructs. Here we show that the ability of Cpf1 to process its own CRISPR RNA (crRNA) can be used to simplify multiplexed genome editing. Using a single customized CRISPR array, we edit up to

  19. Applying decision-making tools to national e-waste recycling policy: an example of Analytic Hierarchy Process.

    Science.gov (United States)

    Lin, Chun-Hsu; Wen, Lihchyi; Tsai, Yue-Mi

    2010-05-01

    As policy making is in essence a process of discussion, decision-making tools have in many cases been proposed to resolve the differences of opinion among the different parties. In our project that sought to promote a country's performance in recycling, we used the Analytic Hierarchy Process (AHP) to evaluate the possibilities and determine the priority of the addition of new mandatory recycled waste, also referred to as Due Recycled Wastes, from candidate waste appliances. The evaluation process started with the collection of data based on telephone interviews and field investigations to understand the behavior of consumers as well as their overall opinions regarding the disposal of certain waste appliances. With the data serving as background information, the research team then implemented the Analytic Hierarchy Process using the information that formed an incomplete hierarchy structure in order to determine the priority for recycling. Since the number of objects to be evaluated exceeded the number that the AHP researchers had suggested, we reclassified the objects into four groups and added one more level of pair-wise comparisons, which substantially reduced the inconsistency in the judgment of the AHP participants. The project was found to serve as a flexible and achievable application of AHP to the environmental policy-making process. In addition, based on the project's outcomes derived from the project as a whole, the research team drew conclusions regarding the government's need to take back 15 of the items evaluated, and suggested instruments that could be used or recycling regulations that could be changed in the future. Further analysis on the top three items recommended by the results of the evaluation for recycling, namely, Compact Disks, Cellular Phones and Computer Keyboards, was then conducted to clarify their concrete feasibility. After the trial period for recycling ordered by the Taiwan Environmental Protection Administration, only Computer

  20. Understanding Editing Behaviors in Multilingual Wikipedia.

    Science.gov (United States)

    Kim, Suin; Park, Sungjoon; Hale, Scott A; Kim, Sooyoung; Byun, Jeongmin; Oh, Alice H

    2016-01-01

    Multilingualism is common offline, but we have a more limited understanding of the ways multilingualism is displayed online and the roles that multilinguals play in the spread of content between speakers of different languages. We take a computational approach to studying multilingualism using one of the largest user-generated content platforms, Wikipedia. We study multilingualism by collecting and analyzing a large dataset of the content written by multilingual editors of the English, German, and Spanish editions of Wikipedia. This dataset contains over two million paragraphs edited by over 15,000 multilingual users from July 8 to August 9, 2013. We analyze these multilingual editors in terms of their engagement, interests, and language proficiency in their primary and non-primary (secondary) languages and find that the English edition of Wikipedia displays different dynamics from the Spanish and German editions. Users primarily editing the Spanish and German editions make more complex edits than users who edit these editions as a second language. In contrast, users editing the English edition as a second language make edits that are just as complex as the edits by users who primarily edit the English edition. In this way, English serves a special role bringing together content written by multilinguals from many language editions. Nonetheless, language remains a formidable hurdle to the spread of content: we find evidence for a complexity barrier whereby editors are less likely to edit complex content in a second language. In addition, we find that multilinguals are less engaged and show lower levels of language proficiency in their second languages. We also examine the topical interests of multilingual editors and find that there is no significant difference between primary and non-primary editors in each language.

  1. Understanding Editing Behaviors in Multilingual Wikipedia.

    Directory of Open Access Journals (Sweden)

    Suin Kim

    Full Text Available Multilingualism is common offline, but we have a more limited understanding of the ways multilingualism is displayed online and the roles that multilinguals play in the spread of content between speakers of different languages. We take a computational approach to studying multilingualism using one of the largest user-generated content platforms, Wikipedia. We study multilingualism by collecting and analyzing a large dataset of the content written by multilingual editors of the English, German, and Spanish editions of Wikipedia. This dataset contains over two million paragraphs edited by over 15,000 multilingual users from July 8 to August 9, 2013. We analyze these multilingual editors in terms of their engagement, interests, and language proficiency in their primary and non-primary (secondary languages and find that the English edition of Wikipedia displays different dynamics from the Spanish and German editions. Users primarily editing the Spanish and German editions make more complex edits than users who edit these editions as a second language. In contrast, users editing the English edition as a second language make edits that are just as complex as the edits by users who primarily edit the English edition. In this way, English serves a special role bringing together content written by multilinguals from many language editions. Nonetheless, language remains a formidable hurdle to the spread of content: we find evidence for a complexity barrier whereby editors are less likely to edit complex content in a second language. In addition, we find that multilinguals are less engaged and show lower levels of language proficiency in their second languages. We also examine the topical interests of multilingual editors and find that there is no significant difference between primary and non-primary editors in each language.

  2. Medical writing, revising and editing

    DEFF Research Database (Denmark)

    Pilegaard, Morten

    2006-01-01

    The globalization of science makes medical writing, editing and revision a rapidly growing field of linguistic study and practice. Medical science texts are written according to uniform, general guidelines and medical genres have become highly conventionalized in terms of structure and linguistic...... form. Medical editing often takes the form of peer review and mainly addresses issues of contents and overall validity. Medical revision incorporates the checking of the macrostructure and the microstructure of the text, its language and style and its suitability for the target reader or client...

  3. Handbook of ecotoxicology, second edition

    Science.gov (United States)

    Hoffman, David J.; Rattner, Barnett A.; Burton, G. Allen; Cairns, John

    2003-01-01

    Handbook of Ecotoxicology, Second Edition focuses on toxic substances and how they affect ecosystems worldwide. It presents methods for quantifying and measuring ecotoxicological effects in the field and in the lab, as well as methods for estimating, predicting, and modeling in ecotoxicology studies. Completely revised and updated with 18 new chapters, this second edition includes contributions from over 75 international experts. Also, a Technical Review Board reviewed all manuscripts for accuracy and currency. This authoritative work is the definitive reference for students, researchers, consultants, and other professionals in the environmental sciences, toxicology, chemistry, biology, and ecology - in academia, industry, and government.

  4. Beginning XML, 5th Edition

    CERN Document Server

    Fawcett, Joe; Quin, Liam R E

    2012-01-01

    A complete update covering the many advances to the XML language The XML language has become the standard for writing documents on the Internet and is constantly improving and evolving. This new edition covers all the many new XML-based technologies that have appeared since the previous edition four years ago, providing you with an up-to-date introductory guide and reference. Packed with real-world code examples, best practices, and in-depth coverage of the most important and relevant topics, this authoritative resource explores both the advantages and disadvantages of XML and addresses the mo

  5. Introducing ZBrush 3rd Edition

    CERN Document Server

    Keller, Eric

    2012-01-01

    Learn ZBrush inside and out with this updated new edition Get totally comfortable sculpting in a digital environment with the latest edition of this bestselling beginner's guide to ZBrush. Fully updated for the newest version of the software, ZBrush 4R3, this book dispels any fears you might have about the difficulty of using ZBrush and soon has you creating realistic, cartoon, and organic models with flair. Learn all the essentials, as you complete fun tutorials on painting, meshes, organic scripting, hard surface sculpting, lighting, rendering, and more. Introduces you to ZBrush, the sculpt

  6. Genome editing comes of age.

    Science.gov (United States)

    Kim, Jin-Soo

    2016-09-01

    Genome editing harnesses programmable nucleases to cut and paste genetic information in a targeted manner in living cells and organisms. Here, I review the development of programmable nucleases, including zinc finger nucleases (ZFNs), TAL (transcription-activator-like) effector nucleases (TALENs) and CRISPR (cluster of regularly interspaced palindromic repeats)-Cas9 (CRISPR-associated protein 9) RNA-guided endonucleases (RGENs). I specifically highlight the key advances that set the foundation for the rapid and widespread implementation of CRISPR-Cas9 genome editing approaches that has revolutionized the field.

  7. Instruments and options for environmental policy during the accession process of EU associated countries in the area of environment and energy. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Cames, M.; Matthes, F.C.; Baer, S.; Oberthuer, S.; Krug, M.; Mez, L.; Tempel, S.

    2001-07-01

    With regard to the leading role of the EU in climate protection policies, it is important to consider the impact of the accession process on EU climate policy. This study includes the analysis of the most important issues related to environment and energy within the accession process, namely: 1) status quo and development of the energy sector and structural CO{sub 2} mitigation options; 2) legal gap assessment and analysis of performance in the accession process; 3) identification of implementation patterns through detailed policy analysis; 4) evaluation of co-operation projects in the field of environment and energy in order to develop new projects that promote the accession process. This volume includes comparative analysis of the five Accession Countries. The detailed analysis of each country is documented in five country reports, each in a separate volume available only on the attached CD. (orig.)

  8. Uneven dietary development: linking the policies and processes of globalization with the nutrition transition, obesity and diet-related chronic diseases.

    Science.gov (United States)

    Hawkes, Corinna

    2006-03-28

    In a "nutrition transition", the consumption of foods high in fats and sweeteners is increasing throughout the developing world. The transition, implicated in the rapid rise of obesity and diet-related chronic diseases worldwide, is rooted in the processes of globalization. Globalization affects the nature of agri-food systems, thereby altering the quantity, type, cost and desirability of foods available for consumption. Understanding the links between globalization and the nutrition transition is therefore necessary to help policy makers develop policies, including food policies, for addressing the global burden of chronic disease. While the subject has been much discussed, tracing the specific pathways between globalization and dietary change remains a challenge. To help address this challenge, this paper explores how one of the central mechanisms of globalization, the integration of the global marketplace, is affecting the specific diet patterns. Focusing on middle-income countries, it highlights the importance of three major processes of market integration: (I) production and trade of agricultural goods; (II) foreign direct investment in food processing and retailing; and (III) global food advertising and promotion. The paper reveals how specific policies implemented to advance the globalization agenda account in part for some recent trends in the global diet. Agricultural production and trade policies have enabled more vegetable oil consumption; policies on foreign direct investment have facilitated higher consumption of highly-processed foods, as has global food marketing. These dietary outcomes also reflect the socioeconomic and cultural context in which these policies are operating. An important finding is that the dynamic, competitive forces unleashed as a result of global market integration facilitates not only convergence in consumption habits (as is commonly assumed in the "Coca-Colonization" hypothesis), but adaptation to products targeted at different

  9. The Social Process of Analyzing Real Water Resource Systems Plans and Management Policies

    Science.gov (United States)

    Loucks, Daniel

    2016-04-01

    Developing and applying systems analysis methods for improving the development and management of real world water resource systems, I have learned, is primarily a social process. This talk is a call for more recognition of this reality in the modeling approaches we propose in the papers and books we publish. The mathematical models designed to inform planners and managers of water systems that we see in many of our journals often seem more complex than they need be. They also often seem not as connected to reality as they could be. While it may be easier to publish descriptions of complex models than simpler ones, and while adding complexity to models might make them better able to mimic or resemble the actual complexity of the real physical and/or social systems or processes being analyzed, the usefulness of such models often can be an illusion. Sometimes the important features of reality that are of concern or interest to those who make decisions can be adequately captured using relatively simple models. Finding the right balance for the particular issues being addressed or the particular decisions that need to be made is an art. When applied to real world problems or issues in specific basins or regions, systems modeling projects often involve more attention to the social aspects than the mathematical ones. Mathematical models addressing connected interacting interdependent components of complex water systems are in fact some of the most useful methods we have to study and better understand the systems we manage around us. They can help us identify and evaluate possible alternative solutions to problems facing humanity today. The study of real world systems of interacting components using mathematical models is commonly called applied systems analyses. Performing such analyses with decision makers rather than of decision makers is critical if the needed trust between project personnel and their clients is to be developed. Using examples from recent and ongoing

  10. Shielded Metal Arc Pipe Welding. Teacher Edition. Second Edition.

    Science.gov (United States)

    Fortney, Clarence; And Others

    This second edition of the shielded metal arc pipe welding curriculum guide presents both basic and advanced pipe welding skills. All specifications for procedure and welder qualification are presented according to national standards. The standards also include the test position for both groove and fillet pipe welding. The guide contains three…

  11. Gas Tungsten Arc Welding and Plasma Arc Cutting. Teacher Edition [and] Student Edition [and] Student Workbook. Second Edition.

    Science.gov (United States)

    Harper, Eddie; Knapp, John

    This packet of instructional materials for a gas tungsten arc welding (GTAW) and plasma arc cutting course is comprised of a teacher edition, student edition, and student workbook. The teacher edition consists of introductory pages and teacher pages. Introductory pages include training and competency profile, state duty/task crosswalk,…

  12. sept edition 2008.cdr

    African Journals Online (AJOL)

    User

    Informed consent in surgical practice sometimes involved a process of sharing decisional authority with the patient when the choice hinged on personal values or preferences. This process, in which a continuous physician-patient decision making partnership agrees on an option of treatment, has been described as the best ...

  13. Abundant RNA editing sites of chloroplast protein-coding genes in Ginkgo biloba and an evolutionary pattern analysis.

    Science.gov (United States)

    He, Peng; Huang, Sheng; Xiao, Guanghui; Zhang, Yuzhou; Yu, Jianing

    2016-12-01

    RNA editing is a posttranscriptional modification process that alters the RNA sequence so that it deviates from the genomic DNA sequence. RNA editing mainly occurs in chloroplasts and mitochondrial genomes, and the number of editing sites varies in terrestrial plants. Why and how RNA editing systems evolved remains a mystery. Ginkgo biloba is one of the oldest seed plants and has an important evolutionary position. Determining the patterns and distribution of RNA editing in the ancient plant provides insights into the evolutionary trend of RNA editing, and helping us to further understand their biological significance. In this paper, we investigated 82 protein-coding genes in the chloroplast genome of G. biloba and identified 255 editing sites, which is the highest number of RNA editing events reported in a gymnosperm. All of the editing sites were C-to-U conversions, which mainly occurred in the second codon position, biased towards to the U_A context, and caused an increase in hydrophobic amino acids. RNA editing could change the secondary structures of 82 proteins, and create or eliminate a transmembrane region in five proteins as determined in silico. Finally, the evolutionary tendencies of RNA editing in different gene groups were estimated using the nonsynonymous-synonymous substitution rate selection mode. The G. biloba chloroplast genome possesses the highest number of RNA editing events reported so far in a seed plant. Most of the RNA editing sites can restore amino acid conservation, increase hydrophobicity, and even influence protein structures. Similar purifying selections constitute the dominant evolutionary force at the editing sites of essential genes, such as the psa, some psb and pet groups, and a positive selection occurred in the editing sites of nonessential genes, such as most ndh and a few psb genes.

  14. Human Genome Editing and Ethical Considerations.

    Science.gov (United States)

    Krishan, Kewal; Kanchan, Tanuj; Singh, Bahadur

    2016-04-01

    Editing human germline genes may act as boon in some genetic and other disorders. Recent editing of the genome of the human embryo with the CRISPR/Cas9 editing tool generated a debate amongst top scientists of the world for the ethical considerations regarding its effect on the future generations. It needs to be seen as to what transformation human gene editing brings to humankind in the times to come.

  15. Buying green! A handbook on green energy procurement. 2nd edition

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-11-10

    Over 2 trillion Euros is spent on public contracts on a yearly basis in the EU, translating to 19 percent of its GDP. ICLEI has been working with the European Commission to produce guidance on green public procurement (GPP) which will help public authorities to reduce their environmental impact, while complying with the procurement rules. The result is the new edition of the Buying Green! handbook. The handbook identifies strategies for GPP, and explains in detail how these can be implemented at each stage of the procurement process. It is intended for public sector procurers but is also a useful reference for policy makers and businesses who are either implementing their own green purchasing or responding to tenders. In addition to explaining how GPP can be implemented under the EU procurement rules, the handbook includes examples of green contracts from across the EU-27. The resource has been fully updated from the previous 2004 edition and includes expanded sections on life-cycle costing (LCC) and the construction, timber, electricity and food and drink sectors.

  16. Strategies of Qualitative Inquiry. Third Edition

    Science.gov (United States)

    Denzin, Norman K., Ed.; Lincoln, Yvonna S., Ed.

    2007-01-01

    "Strategies of Qualitative Inquiry, Third Edition," the second volume in the paperback version of "The SAGE Handbook of Qualitative Research, 3rd Edition," consists of Part III of the handbook ("Strategies of Inquiry"). "Strategies of Qualitative Inquiry, Third Edition" presents the major tactics--historically, the research methods--that…

  17. Promoting School Success. Third Edition

    Science.gov (United States)

    Lovitt, Thomas C.

    2007-01-01

    Like its two predecessors, "Preventing School Dropouts" [C1991] and "Preventing School Failure" [C2000], this third edition is a book about teaching. Although primarily written for teachers, tutors and parents may also find this book helpful. It is a collection of carefully selected teaching techniques aimed at helping young adults learn important…

  18. Money and Schools. Fifth Edition

    Science.gov (United States)

    Thompson, David C.; Crampton, Faith E.; Wood, R. Craig

    2012-01-01

    In the new edition of this essential, all-inclusive text, the authors provide more important research for future principals and others enrolled in graduate-level school finance courses. Written in a style that is highly readable, the book offers strong connections to real-world experiences. Readers get both a broad overview of funding concepts and…

  19. Nuclear Electricity. 5th Edition.

    Science.gov (United States)

    Hore-Lacy, Ian

    Educators must address the need for young people to be informed about both the scientific concepts and the reasons for controversy when dealing with controversial issues. Young people must be given the opportunity to form their own opinions when presented with evidence for conflicting arguments. Previous editions of "Nuclear Electricity" have…

  20. Veterinary Microbiology, 3rd Edition

    Science.gov (United States)

    Veterinary Microbiology, Third Edition is organized into four sections and begins with an updated and expanded introductory section on infectious disease pathogenesis, diagnosis and clinical management. The second section covers bacterial and fungal pathogens, and the third section describes viral d...

  1. Gene editing. Time to reflection.

    OpenAIRE

    Santaló Pedro, Josep

    2017-01-01

    The development of new gene editing technologies and their special characteristics have led to a passionate debate on the suitability and reliability of their use both in plant and animal species and in the human species itself. A brief analysis of the arguments used in this debate as well as a summary of some of the most relevant statements in this regard is made.

  2. A Subdivision-Based Representation for Vector Image Editing.

    Science.gov (United States)

    Liao, Zicheng; Hoppe, Hugues; Forsyth, David; Yu, Yizhou

    2012-11-01

    Vector graphics has been employed in a wide variety of applications due to its scalability and editability. Editability is a high priority for artists and designers who wish to produce vector-based graphical content with user interaction. In this paper, we introduce a new vector image representation based on piecewise smooth subdivision surfaces, which is a simple, unified and flexible framework that supports a variety of operations, including shape editing, color editing, image stylization, and vector image processing. These operations effectively create novel vector graphics by reusing and altering existing image vectorization results. Because image vectorization yields an abstraction of the original raster image, controlling the level of detail of this abstraction is highly desirable. To this end, we design a feature-oriented vector image pyramid that offers multiple levels of abstraction simultaneously. Our new vector image representation can be rasterized efficiently using GPU-accelerated subdivision. Experiments indicate that our vector image representation achieves high visual quality and better supports editing operations than existing representations.

  3. Oligonucleotide-directed mutagenesis for precision gene editing.

    Science.gov (United States)

    Sauer, Noel J; Mozoruk, Jerry; Miller, Ryan B; Warburg, Zachary J; Walker, Keith A; Beetham, Peter R; Schöpke, Christian R; Gocal, Greg F W

    2016-02-01

    Differences in gene sequences, many of which are single nucleotide polymorphisms, underlie some of the most important traits in plants. With humanity facing significant challenges to increase global agricultural productivity, there is an urgent need to accelerate the development of these traits in plants. oligonucleotide-directed mutagenesis (ODM), one of the many tools of Cibus' Rapid Trait Development System (RTDS(™) ) technology, offers a rapid, precise and non-transgenic breeding alternative for trait improvement in agriculture to address this urgent need. This review explores the application of ODM as a precision genome editing technology, with emphasis on using oligonucleotides to make targeted edits in plasmid, episomal and chromosomal DNA of bacterial, fungal, mammalian and plant systems. The process of employing ODM by way of RTDS technology has been improved in many ways by utilizing a fluorescence conversion system wherein a blue fluorescent protein (BFP) can be changed to a green fluorescent protein (GFP) by editing a single nucleotide of the BFP gene (CAC→TAC; H66 to Y66). For example, dependent on oligonucleotide length, applying oligonucleotide-mediated technology to target the BFP transgene in Arabidopsis thaliana protoplasts resulted in up to 0.05% precisely edited GFP loci. Here, the development of traits in commercially relevant plant varieties to improve crop performance by genome editing technologies such as ODM, and by extension RTDS, is reviewed. © 2015 The Authors. Plant Biotechnology Journal published by Society for Experimental Biology and The Association of Applied Biologists and John Wiley & Sons Ltd.

  4. Uneven dietary development: linking the policies and processes of globalization with the nutrition transition, obesity and diet-related chronic diseases

    Science.gov (United States)

    Hawkes, Corinna

    2006-01-01

    In a "nutrition transition", the consumption of foods high in fats and sweeteners is increasing throughout the developing world. The transition, implicated in the rapid rise of obesity and diet-related chronic diseases worldwide, is rooted in the processes of globalization. Globalization affects the nature of agri-food systems, thereby altering the quantity, type, cost and desirability of foods available for consumption. Understanding the links between globalization and the nutrition transition is therefore necessary to help policy makers develop policies, including food policies, for addressing the global burden of chronic disease. While the subject has been much discussed, tracing the specific pathways between globalization and dietary change remains a challenge. To help address this challenge, this paper explores how one of the central mechanisms of globalization, the integration of the global marketplace, is affecting the specific diet patterns. Focusing on middle-income countries, it highlights the importance of three major processes of market integration: (I) production and trade of agricultural goods; (II) foreign direct investment in food processing and retailing; and (III) global food advertising and promotion. The paper reveals how specific policies implemented to advance the globalization agenda account in part for some recent trends in the global diet. Agricultural production and trade policies have enabled more vegetable oil consumption; policies on foreign direct investment have facilitated higher consumption of highly-processed foods, as has global food marketing. These dietary outcomes also reflect the socioeconomic and cultural context in which these policies are operating. An important finding is that the dynamic, competitive forces unleashed as a result of global market integration facilitates not only convergence in consumption habits (as is commonly assumed in the "Coca-Colonization" hypothesis), but adaptation to products targeted at different

  5. Uneven dietary development: linking the policies and processes of globalization with the nutrition transition, obesity and diet-related chronic diseases

    Directory of Open Access Journals (Sweden)

    Hawkes Corinna

    2006-03-01

    Full Text Available Abstract In a "nutrition transition", the consumption of foods high in fats and sweeteners is increasing throughout the developing world. The transition, implicated in the rapid rise of obesity and diet-related chronic diseases worldwide, is rooted in the processes of globalization. Globalization affects the nature of agri-food systems, thereby altering the quantity, type, cost and desirability of foods available for consumption. Understanding the links between globalization and the nutrition transition is therefore necessary to help policy makers develop policies, including food policies, for addressing the global burden of chronic disease. While the subject has been much discussed, tracing the specific pathways between globalization and dietary change remains a challenge. To help address this challenge, this paper explores how one of the central mechanisms of globalization, the integration of the global marketplace, is affecting the specific diet patterns. Focusing on middle-income countries, it highlights the importance of three major processes of market integration: (I production and trade of agricultural goods; (II foreign direct investment in food processing and retailing; and (III global food advertising and promotion. The paper reveals how specific policies implemented to advance the globalization agenda account in part for some recent trends in the global diet. Agricultural production and trade policies have enabled more vegetable oil consumption; policies on foreign direct investment have facilitated higher consumption of highly-processed foods, as has global food marketing. These dietary outcomes also reflect the socioeconomic and cultural context in which these policies are operating. An important finding is that the dynamic, competitive forces unleashed as a result of global market integration facilitates not only convergence in consumption habits (as is commonly assumed in the "Coca-Colonization" hypothesis, but adaptation to

  6. Accessible tourism in Brazil: an exploratory study about the public policies and the process of inclusion of persons with disabilities

    Directory of Open Access Journals (Sweden)

    Donária Coelho Duarte

    2015-12-01

    Full Text Available One of the biggest challenges of society Brazilian is confronting the issue of equality and social exclusion. It is estimated that there are approximately 45 million people with disabilities in Brazil (IBGE, 2010, many of them still unable to enjoy leisure and tourism activities due to their physical limitations and lack of adaptation of the environment. The purpose of this article is to verify if public policy focused tourism for people with disabilities (PWD have been able to meet demands for inclusion these  segment, also seeks the perception of these people as to the inclusion process. The focus of this study, therefore, refers to people who were born or have acquired some kind of permanent limitation, not being object of this survey people who have had temporary physical limitations and/or sporadic or who have reduced mobility. In terms of methodology, a exploratory and qualitative research was made with interviews of semi-structured scripts.  The participants of study were nine managers chosen from representatives of government, of representatives of the tourist trade and of associations of people with disabilities. From the interviews with the public, given the diversity of actions and their characteristics, it proposed the classification of programs/government actions. As result, the research shows that the government has to attack the problem and sought to create and implement policies directed to this segment. However, people with disabilities consider that what has been done is not enough to include them really in tourist activities and say they are not being heard enough. All disabled associations mentions that the limitations/difficult environment hamper achievement of tourism. It was noticed also that the private sector does not consider the disabled person as a consumer public and that are not done research to understand the profile and the needs of this segment. Both the private sector as PWD associations, showed little

  7. Harnessing CRISPR-Cas systems for bacterial genome editing.

    Science.gov (United States)

    Selle, Kurt; Barrangou, Rodolphe

    2015-04-01

    Manipulation of genomic sequences facilitates the identification and characterization of key genetic determinants in the investigation of biological processes. Genome editing via clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated (Cas) constitutes a next-generation method for programmable and high-throughput functional genomics. CRISPR-Cas systems are readily reprogrammed to induce sequence-specific DNA breaks at target loci, resulting in fixed mutations via host-dependent DNA repair mechanisms. Although bacterial genome editing is a relatively unexplored and underrepresented application of CRISPR-Cas systems, recent studies provide valuable insights for the widespread future implementation of this technology. This review summarizes recent progress in bacterial genome editing and identifies fundamental genetic and phenotypic outcomes of CRISPR targeting in bacteria, in the context of tool development, genome homeostasis, and DNA repair. Copyright © 2015 Elsevier Ltd. All rights reserved.

  8. The impact of the European Environment and Health Process on UK environment and health policy, plans and practice: what difference has it made?

    Science.gov (United States)

    Capleton, Alexander C; Stevens, Jane; Harrison, Paul T C

    2005-10-01

    The European Environment and Health Process (EEHP), led by the World Health Organization (WHO) Regional Office for Europe, aims to support WHO Member States as they plan and implement national and international environment and health policies. An evaluation of the impact of the EEHP in the UK was conducted in preparation for the fourth Ministerial Conference on Environment and Health in Budapest, 2004. The evaluation identified a number of impacts and influences of the EEHP. This concluded that the process had only a marginal direct influence on policy within the UK. However, it was also concluded that the process had resulted in several indirect influences, including better cooperation between government departments, greater awareness of environment and health issues from an international perspective, and a higher political profile of environment and health issues. A few outcomes of the EEHP also appear to have been taken into account in some national and local policy documents. The National Environmental Health Action Plan, which was produced as a direct result of the EEHP, appears to have had little direct impact in the UK, probably because of the lack of an implementation process and indicators, and because it was superseded by other policy initiatives relatively soon after publication. A need for better coordination and promotion of the EEHP amongst stakeholders responsible for environment and health policy areas was also identified.

  9. Collaborative Work and Language Learners' Identities When Editing Academic Texts

    Science.gov (United States)

    Caviedes, Lorena; Meza, Angélica; Rodriguez, Ingrid

    2016-01-01

    This paper presents a qualitative case study that involved three groups of English as a foreign language pre-service teachers at a Colombian private university. Each group attended tutoring sessions during an academic semester. Along these sessions, students were asked to work collaboratively in the editing process of some chapters of their thesis…

  10. Action Research: Improving Schools and Empowering Educators. Third Edition

    Science.gov (United States)

    Mertler, Craig A.

    2011-01-01

    Written for pre- and in-service educators, this "Third Edition" of Craig A. Mertler's "Action Research: Improving Schools and Empowering Educators" introduces the process of conducting one's own classroom- or school-based action research in conjunction with everyday instructional practices and activities. The text provides educators with the…

  11. Weeding Library Collections: Library Weeding Methods. Fourth Edition.

    Science.gov (United States)

    Slote, Stanly J.

    Weeding is one of the best ways to make long-term improvements to library collections, but it is also a difficult and sometimes painful task. In the tradition of previous editions, this book guides librarians in the process of methodical and efficient weeding. The book shows how to identify core collections versus the weedable items. The approach…

  12. Special Edition: Environment in Sustainable Development

    Directory of Open Access Journals (Sweden)

    Stephen Morse

    2014-11-01

    Full Text Available When we were invited by the editors of Sustainability to put together a special edition on “Environment in Sustainable Development” our first reaction was to question whether this was really needed. After all, the environment has long been regarded as a central plank in sustainability and there are countless articles and books published on an annual basis that explore the impact of our economic and social activities on our environment. Just what is it that a special edition can achieve? What new angles could we hope to provide? Our initial thinking was to link the special edition to a particular, almost unique, location in time rather than space. We are in the process of recovering, albeit stuttering, from the deepest economic crash experienced by the European and North American economies. The crash has brought some national economies to their knees and, if economic commentators are to be believed, almost destroyed the Euro. Recovery from that crash has been slow and it is arguable whether at the time of writing this has developed much momentum. There is still the skewed perception that prosperity equals economic growth and that economic growth can take place without real (sustainable development or by simply implementing austerity measures and surely without people’s participation. An analogy from National Parks worldwide is when conservation agencies try to enforce protection without local people’s support. All such attempts have either failed or resurrected only once people’s involvement was secured and guaranteed. The unidirectional austerity measures imposed mainly in the countries of southern Europe have destroyed social cohesion leaving deeply wounded societies, while at the same time have also put up for grabs important assets (including natural capital in each of these countries and therefore in jeopardy even their long term recovery.

  13. IT Policy Archive

    Data.gov (United States)

    National Aeronautics and Space Administration — CIO defines IT processes and policies. The CIO defines the development processes, milestones, review gates, and the overall policies for all capital planning,...

  14. An Analysis of the Economic Impact of Cap-and-Trade Policy on the California Food Processing Industry: A Look at Processed Tomatoes and Dairy Products

    OpenAIRE

    Paggi, Mechel S.; Yamazaki, Fumiko; Konduru, Srinivasa

    2014-01-01

    California Cap-and-Trade policy, sets a statewide limit on sources responsible for an estimated 85 percent of the state’s greenhouse gas emissions. To maintain the cap as per the policy, individual industrial facilities in California must obtain enough allowances to cover their emissions either by purchasing allowances at auction or reducing their emissions by operating more efficiently. This research report analyses the economic impact of the Cap-and-Trade policy on the California food pro...

  15. State Teacher Policy Yearbook, 2009. Hawaii

    Science.gov (United States)

    National Council on Teacher Quality, 2009

    2009-01-01

    The Hawaii edition of the National Council on Teacher Quality's (NCTQ's) 2009 "State Teacher Policy Yearbook" is the third annual look at state policies impacting the teaching profession. It is hoped that this report will help focus attention on areas where state policymakers can make changes that will have a positive impact on teacher…

  16. State Teacher Policy Yearbook, 2009. Nevada

    Science.gov (United States)

    National Council on Teacher Quality, 2009

    2009-01-01

    The Nevada edition of the National Council on Teacher Quality's (NCTQ's) 2009 "State Teacher Policy Yearbook" is the third annual look at state policies impacting the teaching profession. It is hoped that this report will help focus attention on areas where state policymakers can make changes that will have a positive impact on teacher…

  17. Diesel Technology: Steering and Suspension. Second Edition. Teacher Edition [and] Student Edition.

    Science.gov (United States)

    Miller, Roger; Scarberry, Terry; Tesch, Carl; Kellum, Mary

    These teacher and student editions on steering and suspension are part of the diesel mechanics series of instructional materials. The series aligns with the medium/heavy duty truck task list developed by the National Automotive Technicians Education Foundation and used by the National Institute for Automotive Service Excellence in the…

  18. Diesel Technology: Safety Skills. Teacher Edition [and] Student Edition. Second Edition.

    Science.gov (United States)

    Kellum, Mary

    Teacher and student editions of this document are one in a series of competency-based instructional materials for diesel technology programs. The series aligns with the medium/heavy diesel duty truck task list used by the National Institute for Automotive Service Excellence in the certification of medium/heavy duty truck technicians. Introductory…

  19. Country Nuclear Power Profiles - 2007 Edition

    International Nuclear Information System (INIS)

    2008-01-01

    The preparation of Country Nuclear Power Profiles (CNPP) was initiated within the framework of the IAEA's programme on assessment and feedback of nuclear power plant performance. It responded to a need for a database and a technical publication containing a description of the energy and economic situation, the energy and the electricity sector, and the primary organizations involved in nuclear power in IAEA Member States. It covers background information on the status and development of nuclear power programmes in countries having nuclear plants in operation and/or plants under construction. This is the 2007 edition issued on CD-ROM and Web pages. It updates the country information, in general, to the end of 2006 for 39 countries. The CNPP is updated based on information voluntarily provided by participating IAEA Member States. Participants include the 30 countries that have operating nuclear power plants, as well as nine countries having past or planned nuclear power programmes (Bangladesh, Egypt, Indonesia, the Islamic Republic of Iran, Italy, Kazakhstan, Poland, Turkey, and Vietnam). For the 2007 edition, 21 countries provided information to the IAEA to update their profiles. For the 18 other countries, the IAEA updated the profile statistical tables on nuclear power, energy development, and economic indicators based on information from IAEA and World Bank databases. These 18 countries are Argentina, Belgium, Bulgaria, Canada, China, Egypt, Finland, Indonesia, Japan, Mexico, Netherlands, Poland, Romania, Slovenia, South Africa, Spain, Switzerland, and Ukraine. Overall, the CNPP reviews the organizational and industrial aspects of nuclear power programmes in participating countries, and provides information about the relevant legislative, regulatory and international frameworks in each country. It compiles the current issues in the new environment within which the electricity and nuclear sector operates, i.e. energy policy, and privatization and deregulation in

  20. Water Pollution, Teachers' Edition.

    Science.gov (United States)

    Lavaroni, Charles W.; And Others

    One of three in a series about pollution, this teacher's guide for a unit on water pollution is designed for use in junior high school grades. It offers suggestions for extending the information and activities contained in the textual material for students. Chapter 1 discusses the problem of water pollution and involves students in processes of…

  1. Air Pollution, Teachers' Edition.

    Science.gov (United States)

    Lavaroni, Charles W.; O'Donnell, Patrick A.

    One of three in a series about pollution, this teacher's guide for a unit on air pollution is designed for use in junior high school grades. It offers suggestions for extending the information and activities contained in the textual material for students. Chapter 1 discusses the problem of air pollution and involves students in processes of…

  2. UN-EDITED VERSION

    Indian Academy of Sciences (India)

    38

    pharmacological intervention that slows the aging process and extends both lifespan and health span (Fontana et al. 2010;. Mitchell et al. 2010). DR is a decrease in food intake without causing malnutrition. Various types of DR regimes exist that ...

  3. Are social security policies for Chinese landless farmers really effective on health in the process of Chinese rapid urbanization? A study on the effect of social security policies for Chinese landless farmers on their health-related quality of life.

    Science.gov (United States)

    Liang, Ying; Lu, Wanyi; Wu, Wei

    2014-01-15

    on the HRQOL of landless farmers. As regards social security policies, the land acquisition compensation policy and the employment security policy produce the greatest and weakest influences on the HRQOL of landless farmers, respectively. The rapid urbanization in China has deprived many farmers of their lands and of the benefits of urbanization. These farmers are often in a disadvantaged position in the land acquisition process. Statistic analysis in this paper shows that the satisfaction of landless farmers with their social security policies positively influences their HRQOL. The implementation and improvement of social security policies is very important for the long-term and sustainable development of these landless farmers.

  4. Addressing the challenges to health sector decentralization in Nepal: an inquiry into the policy and implementation processes.

    Science.gov (United States)

    Dhakal, R; Ratanawijitrasin, S; Srithamrongsawat, S

    2009-09-01

    The objective of the study was to analyze the status and explore the challenges to decentralization policy implementation in Nepal. Thirty seven key informants rich in experience and knowledge, seven focus group discussions, observation of six health facilities and analysis of about 25 key policy documents provided the data for this study. The study identified the challenges to the implementation of decentralization reforms in the public health sector as: (i) centralised and weak management and programming practices of the government; (ii) weak legal and institutional framework; (iii) conflicting policy objectives; (iv) lack of implementation strategy; (v) poor financial and human resource management system; (vi) lack of adequate preparation for managing the reform; (vii) weak capacity at all levels; (viii) political instability. It was revealed that the implementation of the policy in Nepal was extremely poor as many of the important policy measures were either never initiated or they were only partially implemented. The challenges lie both at - policy design and implementation phase. Clear policy objectives, appropriate structure, sound planning, financing and human resources policy, adequate capacity, responsive information system, defined service packages, active participation of stakeholders and a conducive socio-political environment are considered imperative for successful implementation of the policy. Preparation for managing reform implementation at national and district levels is prerequisite for decentralization to work. Pushing for decentralization in a politically fragile environment may rather lead to further fragmentation, instead of strengthening government legitimacy.

  5. Statistical Physics Approaches to RNA Editing

    Science.gov (United States)

    Bundschuh, Ralf

    2012-02-01

    The central dogma of molecular Biology states that DNA is transcribed base by base into RNA which is in turn translated into proteins. However, some organisms edit their RNA before translation by inserting, deleting, or substituting individual or short stretches of bases. In many instances the mechanisms by which an organism recognizes the positions at which to edit or by which it performs the actual editing are unknown. One model system that stands out by its very high rate of on average one out of 25 bases being edited are the Myxomycetes, a class of slime molds. In this talk we will show how the computational methods and concepts from statistical Physics can be used to analyze DNA and protein sequence data to predict editing sites in these slime molds and to guide experiments that identified previously unknown types of editing as well as the complete set of editing events in the slime mold Physarum polycephalum.

  6. Progress and prospects in plant genome editing.

    Science.gov (United States)

    Yin, Kangquan; Gao, Caixia; Qiu, Jin-Long

    2017-07-31

    The emergence of sequence-specific nucleases that enable genome editing is revolutionizing basic and applied biology. Since the introduction of CRISPR-Cas9, genome editing has become widely used in transformable plants for characterizing gene function and improving traits, mainly by inducing mutations through non-homologous end joining of double-stranded breaks generated by CRISPR-Cas9. However, it would be highly desirable to perform precision gene editing in plants, especially in transformation-recalcitrant species. Recently developed Cas9 variants, novel RNA-guided nucleases and base-editing systems, and DNA-free CRISPR-Cas9 delivery methods now provide great opportunities for plant genome engineering. In this Review Article, we describe the current status of plant genome editing, focusing on newly developed genome editing tools and methods and their potential applications in plants. We also discuss the specific challenges facing plant genome editing, and future prospects.

  7. Polymer chemistry (revised edition)

    International Nuclear Information System (INIS)

    Kim, Jae Mum

    1987-02-01

    This book deals with polymer chemistry, which is divided into fourteen chapters. The contents of this book are development of polymer chemistry, conception of polymer, measurement of polymer chemistry, conception of polymer, measurement of polymer, molecule structure of polymer, thermal prosperities of solid polymer, basic theory of polymerization, radical polymerization, ion polymerization, radical polymerization, copolymerization, polymerization by step-reaction, polymer reaction, crown polymer and inorganic polymer on classification and process of creation such as polymeric sulfur and carbon fiber.

  8. Condition-specific RNA editing in the coral symbiont Symbiodinium microadriaticum

    KAUST Repository

    Liew, Yi Jin

    2017-03-01

    RNA editing is a rare post-transcriptional event that provides cells with an additional level of gene expression regulation. It has been implicated in various processes including adaptation, viral defence and RNA interference; however, its potential role as a mechanism in acclimatization has just recently been recognised. Here, we show that RNA editing occurs in 1.6% of all nuclear-encoded genes of Symbiodinium microadriaticum, a dinoflagellate symbiont of reef-building corals. All base-substitution edit types were present, and statistically significant motifs were associated with three edit types. Strikingly, a subset of genes exhibited condition-specific editing patterns in response to different stressors that resulted in significant increases of non-synonymous changes. We posit that this previously unrecognised mechanism extends this organism’s capability to respond to stress beyond what is encoded by the genome. This in turn may provide further acclimatization capacity to these organisms, and by extension, their coral hosts.

  9. [The application of genome editing in identification of plant gene function and crop breeding].

    Science.gov (United States)

    Zhou, Xiang-chun; Xing, Yong-zhong

    2016-03-01

    Plant genome can be modified via current biotechnology with high specificity and excellent efficiency. Zinc finger nucleases (ZFN), transcription activator-like effector nucleases (TALEN) and clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated 9 (Cas9) system are the key engineered nucleases used in the genome editing. Genome editing techniques enable gene targeted mutagenesis, gene knock-out, gene insertion or replacement at the target sites during the endogenous DNA repair process, including non-homologous end joining (NHEJ) and homologous recombination (HR), triggered by the induction of DNA double-strand break (DSB). Genome editing has been successfully applied in the genome modification of diverse plant species, such as Arabidopsis thaliana, Oryza sativa, and Nicotiana tabacum. In this review, we summarize the application of genome editing in identification of plant gene function and crop breeding. Moreover, we also discuss the improving points of genome editing in crop precision genetic improvement for further study.

  10. The influence of bureaucrats on the policy-making process in the former Soviet Union: The case of Chernobyl

    Science.gov (United States)

    Kerner, Lucy Alexandra

    The events that started to unfurl in the former Soviet Union in the beginning of the 1990s and that ended with the disintegration of the USSR caught many sovietologists, and specialists on former communist and socialist regimes by surprise. Major theories and analyses developed and successfully used in such areas as Comparative Politics, International Relations, and Comparative Socialism turned out to be impotent to foresee the approach of the dramatic changes. Noticing the growing significance of and influence on the policy making process of numerous bureaucracies, this study has applied alternative approaches that were developed in such fields as Organizational Theory, Bureaucratic Behavior, and Public Policy. The issue of bureaucratic performance in the former USSR became the central focal point of the study. Methods suggested by specialists in these fields permitted measurement of the performance of different bureaucratic medical institutions during and after the Chernobyl crisis. Utilization of performance measurements helped uncover several important phenomena. One, that performance of the Soviet medical institutions/organizations and bureaucracies that they housed reached an ultimate dysfunctional stage. It became counterproductive to the point that we can brand it pathological. The characteristic feature of pathological performance is that its outcomes (final results) have a totally counterproductive effect on the external environment and on the community which uses its services and/or products. In the case of Chernobyl it was medical services that were either very poorly provided to the victims of the accident or totally withheld from them The result was a manifold increase in different illnesses and deaths among the population affected by the accident. Second, behavior and performance of the medical bureaucracies in comparison with the behavior and performance of other Soviet bureaucracies has shown that it was not unique. This counterproductive behavior

  11. Sewer Processes

    DEFF Research Database (Denmark)

    Hvitved-Jacobsen, Thorkild; Vollertsen, Jes; Nielsen, Asbjørn Haaning

    Since the first edition was published over a decade ago, advancements have been made in the design, operation, and maintenance of sewer systems, and new problems have emerged. For example, sewer processes are now integrated in computer models, and simultaneously, odor and corrosion problems caused...... and valuable information on the sewer as a chemical and biological reactor. It focuses on how to predict critical impacts and control adverse effects. It also provides an integrated description of sewer processes in modeling terms. This second edition is full of illustrative examples and figures, includes...... of odor formation and prediction • Details the WATS sewer process model • Highlights the importance of aerobic, anoxic, and anaerobic processes Sewer Processes: Microbial and Chemical Process Engineering of Sewer Networks, Second Edition, provides a basis for up-to-date understanding and modeling of sewer...

  12. Editing as a psychological practice.

    Science.gov (United States)

    Beebe, John

    2006-06-01

    The experience of the Jungian analyst in the role of editor of manuscripts by creative colleagues is examined. Historical precedents include Michael Fordham's editorial correspondence with Jung around the latter's synchronicity essay; Jung's handling of manuscripts submitted by Sabina Spielrein to the Jahrbuch für psychoanalytische und psychopathologische Forschungen and various authors to the Zentralblatt für Psychotherapie und ihre Grenzgebiete, and the author's close editing of a paper submitted by Andrew Samuels to the Journal of Analytical Psychology. In addition to mustering an adequate amount of generosity, erudition, and availability, the analytic editor must know how to clarify a psychological argument and to gauge the psychological impact of the written text. Notwithstanding transference/countertransference phenomena that can emerge around issues of competition, envy, and territoriality when author and editor are also fellow-authors working in the same field, the editor needs to be comfortable about serving as the author's selfobject and midwife. From an analytic perspective, although communicating decisions about the best way to put ideas into words can sometimes attract transference to the editor, the more profound transference that analysts experience in the editing situation is toward the text being edited, which helps to motivate donated time spent caring for journal manuscripts.

  13. Peer-editing Practice in the Writing Classroom: Benefits and Drawbacks

    Directory of Open Access Journals (Sweden)

    Ann Rosnida Md. Deni

    2011-01-01

    Full Text Available Small scale studies have shown that peer-editing is beneficial to students as it increases their awareness of the complex process of writing, it improves their knowledge of and skills in writing and helps them become more autonomous in learning. Teachers too may benefit from peer-editing as this practice discloses invaluable information on students’ writing weaknesses and strengths: and teachers’ teaching effectiveness. This is a small scale study conducted on fifteen first-year degree students majoring in Tourism to view the usefulness of peer-editing practice in enhancing their writing skills. Retrospective notes were taken to record students’ receptiveness and reaction towards peer editing practice: students writing samples and peer- editing questionnaires were analyzed to view students’ revisions and comments; and an open— ended questionnaire was distributed to identify students perceptions of peer—editing practice in the writing classroom. Analysis of data gathered revealed that peer-editing practice benefitted both the teacher and most of her students as it exposed important information that could improve her teaching of writing and her students’ writing practices. Data analysis also. however, discloses that peer-editing practice may have adverse effects on students’ motivation and improvement in writing if they are not deployed properly.

  14. Review: Questioning Ireland: debates in political philosophy and public policy

    OpenAIRE

    Sheehan, Helena

    2000-01-01

    This is a review of a collection of essays entitled Questioning Ireland: debates in political philosophy and public policy, edited by Joseph Dunne, Attracta Ingram and Frank Litton, published in Dublin by the Institute of Public Administration in 2000.

  15. Role of tRNAPro in pretransfer editing of alanine by prolyl-tRNA synthetase

    Directory of Open Access Journals (Sweden)

    Boyarshin K. S.

    2013-09-01

    Full Text Available Aim. To characterize the process of tRNA-dependent pretransfer edi- ting of alanine by prolyl-tRNA synthetase of bacteria Enterococcus faecalis (ProRSEf. Methods. Velocity of the editing processes in vitro was determined by ATP hydrolysis by ProRSEf. Pretransfer and posttransfer editing were experimentally separated by site-directed mutagenesis. Results. tRNA-dependent pretransfer editing is characterized by three-fold larger velocity then tRNA-independent editing. Effectivity of the process depends on the presence of 2'-hydroxyle group of A76 tRNAPro. In the absence of tRNAPro selective release of alanyl-AMP occurs simultaneously with tRNA-independent pretransfer editing. Released alanyl-AMP can be re-bound and hydrolyzed. Conclusions. tRNA-dependent pretransfer editing of alanine by ProRSEf is the catalytic mechanism, mediated by 2'-hydroxyl group of A76 tRNAPro. In the absence of tRNAPro tRNA-independent pretransfer editing and selective release of alanyl-AMP occur.

  16. The Health Policy Process in Vietnam: Going Beyond Kingdon’s Multiple Streams Theory Comment on “Shaping the Health Policy Agenda: The Case of Safe Motherhood Policy in Vietnam”

    Directory of Open Access Journals (Sweden)

    Sumit Kane

    2016-07-01

    Full Text Available This commentary reflects upon the article along three broad lines. It reflects on the theoretical choices and omissions, particularly highlighting why it is important to adapt the multiple streams framework (MSF when applying it in a socio-political context like Vietnam’s. The commentary also reflects upon the analytical threads tackled by Ha et al; for instance, it highlights the opportunities offered by, and raises questions about the centrality of the Policy Entrepreneur in getting the policy onto the political agenda and in pushing it through. The commentary also dwells on the implications of the article for development aid policies and practices. Throughout, the commentary signposts possible themes for Ha et al to consider for further analysis, and more generally, for future research using Kingdon’s multiple streams theory.

  17. Technology Catalogue. First edition

    Energy Technology Data Exchange (ETDEWEB)

    1994-02-01

    The Department of Energy`s Office of Environmental Restoration and Waste Management (EM) is responsible for remediating its contaminated sites and managing its waste inventory in a safe and efficient manner. EM`s Office of Technology Development (OTD) supports applied research and demonstration efforts to develop and transfer innovative, cost-effective technologies to its site clean-up and waste management programs within EM`s Office of Environmental Restoration and Office of Waste Management. The purpose of the Technology Catalogue is to provide performance data on OTD-developed technologies to scientists and engineers assessing and recommending technical solutions within the Department`s clean-up and waste management programs, as well as to industry, other federal and state agencies, and the academic community. OTD`s applied research and demonstration activities are conducted in programs referred to as Integrated Demonstrations (IDs) and Integrated Programs (IPs). The IDs test and evaluate.systems, consisting of coupled technologies, at specific sites to address generic problems, such as the sensing, treatment, and disposal of buried waste containers. The IPs support applied research activities in specific applications areas, such as in situ remediation, efficient separations processes, and site characterization. The Technology Catalogue is a means for communicating the status. of the development of these innovative technologies. The FY93 Technology Catalogue features technologies successfully demonstrated in the field through IDs and sufficiently mature to be used in the near-term. Technologies from the following IDs are featured in the FY93 Technology Catalogue: Buried Waste ID (Idaho National Engineering Laboratory, Idaho); Mixed Waste Landfill ID (Sandia National Laboratories, New Mexico); Underground Storage Tank ID (Hanford, Washington); Volatile organic compound (VOC) Arid ID (Richland, Washington); and VOC Non-Arid ID (Savannah River Site, South Carolina).

  18. Identifying the Machine Translation Error Types with the Greatest Impact on Post-editing Effort.

    Science.gov (United States)

    Daems, Joke; Vandepitte, Sonia; Hartsuiker, Robert J; Macken, Lieve

    2017-01-01

    Translation Environment Tools make translators' work easier by providing them with term lists, translation memories and machine translation output. Ideally, such tools automatically predict whether it is more effortful to post-edit than to translate from scratch, and determine whether or not to provide translators with machine translation output. Current machine translation quality estimation systems heavily rely on automatic metrics, even though they do not accurately capture actual post-editing effort. In addition, these systems do not take translator experience into account, even though novices' translation processes are different from those of professional translators. In this paper, we report on the impact of machine translation errors on various types of post-editing effort indicators, for professional translators as well as student translators. We compare the impact of MT quality on a product effort indicator (HTER) with that on various process effort indicators. The translation and post-editing process of student translators and professional translators was logged with a combination of keystroke logging and eye-tracking, and the MT output was analyzed with a fine-grained translation quality assessment approach. We find that most post-editing effort indicators (product as well as process) are influenced by machine translation quality, but that different error types affect different post-editing effort indicators, confirming that a more fine-grained MT quality analysis is needed to correctly estimate actual post-editing effort. Coherence, meaning shifts, and structural issues are shown to be good indicators of post-editing effort. The additional impact of experience on these interactions between MT quality and post-editing effort is smaller than expected.

  19. Experimental Stochatics (2nd edition)

    International Nuclear Information System (INIS)

    Wiberg, P

    2004-01-01

    Otto Moeschlin and his co-authors have written a book about simulation of stochastic systems. The book comes with a CD-ROM that contains the experiments discussed in the book, and the text from the book is repeated on the CD-ROM. According to the authors, the aim of the book is to give a quick introduction to stochastic simulation for 'all persons interested in experimental stochastics'. To please this diverse audience, the authors offer a book that has four parts. Part 1, called 'Artificial Randomness', is the longest of the four parts. It gives an overview of the generation, testing and basic usage of pseudo random numbers in simulation. Although algorithms for generating sequences of random numbers are fundamental to simulation, it is a slightly unusual choice to give it such weight in comparison to other algorithmic topics. The remaining three parts consist of simulation case studies. Part 2, 'Stochastic Models', treats four problems - Buffon's needle, a queuing system, and two problems related to the kinetic theory of gases. Part 3 is called 'Stochastic Processes' and discusses the simulation of discrete time Markov chains, birth-death processes, Brownian motion and diffusions. The last section of Part 3 is about simulation as a tool to understand the traffic flow in a system controlled by stoplights, an area of research for the authors. Part 4 is called 'Evaluation of Statistical Procedures'. This section contains examples where simulation is used to test the performance of statistical methods. It covers four examples: the Neymann-Pearson lemma, the Wald sequential test, Bayesian point estimation and Hartigan procedures. The CD-ROM contains an easy-to-install software package that runs under Microsoft Windows. The software contains the text and simulations from the book. What I found most enjoyable about this book is the number of topics covered in the case studies. The highly individual selection of applications, which may serve as a source of inspiration

  20. Comparing different policy scenarios to reduce the consumption of ultra-processed foods in UK: impact on cardiovascular disease mortality using a modelling approach.

    Science.gov (United States)

    Moreira, Patricia V L; Baraldi, Larissa Galastri; Moubarac, Jean-Claude; Monteiro, Carlos Augusto; Newton, Alex; Capewell, Simon; O'Flaherty, Martin

    2015-01-01

    The global burden of non-communicable diseases partly reflects growing exposure to ultra-processed food products (UPPs). These heavily marketed UPPs are cheap and convenient for consumers and profitable for manufacturers, but contain high levels of salt, fat and sugars. This study aimed to explore the potential mortality reduction associated with future policies for substantially reducing ultra-processed food intake in the UK. We obtained data from the UK Living Cost and Food Survey and from the National Diet and Nutrition Survey. By the NOVA food typology, all food items were categorized into three groups according to the extent of food processing: Group 1 describes unprocessed/minimally processed foods. Group 2 comprises processed culinary ingredients. Group 3 includes all processed or ultra-processed products. Using UK nutrient conversion tables, we estimated the energy and nutrient profile of each food group. We then used the IMPACT Food Policy model to estimate reductions in cardiovascular mortality from improved nutrient intakes reflecting shifts from processed or ultra-processed to unprocessed/minimally processed foods. We then conducted probabilistic sensitivity analyses using Monte Carlo simulation. Approximately 175,000 cardiovascular disease (CVD) deaths might be expected in 2030 if current mortality patterns persist. However, halving the intake of Group 3 (processed) foods could result in approximately 22,055 fewer CVD related deaths in 2030 (minimum estimate 10,705, maximum estimate 34,625). An ideal scenario in which salt and fat intakes are reduced to the low levels observed in Group 1 and 2 could lead to approximately 14,235 (minimum estimate 6,680, maximum estimate 22,525) fewer coronary deaths and approximately 7,820 (minimum estimate 4,025, maximum estimate 12,100) fewer stroke deaths, comprising almost 13% mortality reduction. This study shows a substantial potential for reducing the cardiovascular disease burden through a healthier food system

  1. Guidelines for the editing of dissertations and theses: A survey of ...

    African Journals Online (AJOL)

    The general lack of explicit policy guidelines for the editing of dissertations and theses in South Africa, and the variation among sets of guidelines that do exist, create a possible ethical dilemma, with potential ramifications for the editor, the postgraduate student and the highereducation institution from which the qualification ...

  2. Guidelines for the editing of dissertations and theses: A survey of ...

    African Journals Online (AJOL)

    This article presents the findings of an empirical study undertaken to investigate South African editors' perceptions of the tasks and responsibilities of the editor working with dissertations and theses. The general lack of explicit policy guidelines for the editing of dissertations and theses in South Africa, and the variation ...

  3. What Can We Learn About the Processes of Regulation of Tuberculosis Medicines From the Experiences of Health Policy and System Actors in India, Tanzania, and Zambia?

    Directory of Open Access Journals (Sweden)

    Kabir Sheikh

    2016-07-01

    Full Text Available Background: The unregulated availability and irrational use of tuberculosis (TB medicines is a major issue of public health concern globally. Governments of many low- and middle-income countries (LMICs have committed to regulating the quality and availability of TB medicines, but with variable success. Regulation of TB medicines remains an intractable challenge in many settings, but the reasons for this are poorly understood. The objective of this paper is to elaborate processes of regulation of quality and availability of TB medicines in three LMICs – India, Tanzania, and Zambia – and to understand the factors that constrain and enable these processes. Methods: We adopted the action-centred approach of policy implementation analysis that draws on the experiences of relevant policy and health system actors in order to understand regulatory processes. We drew on data from three case studies commissioned by the World Health Organization (WHO, on the regulation of TB medicines in India, Tanzania, and Zambia. Qualitative research methods were used, including in-depth interviews with 89 policy and health system actors and document review. Data were organized thematically into accounts of regulators’ authority and capacity; extent of policy implementation; and efficiency, transparency, and accountability. Results: In India, findings included the absence of a comprehensive policy framework for regulation of TB medicines, constraints of authority and capacity of regulators, and poor implementation of prescribing and dispensing norms in the majority private sector. Tanzania had a policy that restricted import, prescribing and dispensing of TB medicines to government operators. Zambia procured and dispensed TB medicines mainly through government services, albeit in the absence of a single policy for restriction of medicines. Three cross-cutting factors emerged as crucially influencing regulatory processes - political and stakeholder support for

  4. What Can We Learn About the Processes of Regulation of Tuberculosis Medicines From the Experiences of Health Policy and System Actors in India, Tanzania, and Zambia?

    Science.gov (United States)

    Sheikh, Kabir; Uplekar, Mukund

    2016-03-09

    The unregulated availability and irrational use of tuberculosis (TB) medicines is a major issue of public health concern globally. Governments of many low- and middle-income countries (LMICs) have committed to regulating the quality and availability of TB medicines, but with variable success. Regulation of TB medicines remains an intractable challenge in many settings, but the reasons for this are poorly understood. The objective of this paper is to elaborate processes of regulation of quality and availability of TB medicines in three LMICs - India, Tanzania, and Zambia - and to understand the factors that constrain and enable these processes. We adopted the action-centred approach of policy implementation analysis that draws on the experiences of relevant policy and health system actors in order to understand regulatory processes. We drew on data from three case studies commissioned by the World Health Organization (WHO), on the regulation of TB medicines in India, Tanzania, and Zambia. Qualitative research methods were used, including in-depth interviews with 89 policy and health system actors and document review. Data were organized thematically into accounts of regulators' authority and capacity; extent of policy implementation; and efficiency, transparency, and accountability. In India, findings included the absence of a comprehensive policy framework for regulation of TB medicines, constraints of authority and capacity of regulators, and poor implementation of prescribing and dispensing norms in the majority private sector. Tanzania had a policy that restricted import, prescribing and dispensing of TB medicines to government operators. Zambia procured and dispensed TB medicines mainly through government services, albeit in the absence of a single policy for restriction of medicines. Three cross-cutting factors emerged as crucially influencing regulatory processes - political and stakeholder support for regulation, technical and human resource capacity of

  5. A framework for an institutional high level security policy for the processing of medical data and their transmission through the Internet.

    Science.gov (United States)

    Ilioudis, C; Pangalos, G

    2001-01-01

    The Internet provides many advantages when used for interaction and data sharing among health care providers, patients, and researchers. However, the advantages provided by the Internet come with a significantly greater element of risk to the confidentiality, integrity, and availability of information. It is therefore essential that Health Care Establishments processing and exchanging medical data use an appropriate security policy. To develop a High Level Security Policy for the processing of medical data and their transmission through the Internet, which is a set of high-level statements intended to guide Health Care Establishment personnel who process and manage sensitive health care information. We developed the policy based on a detailed study of the existing framework in the EU countries, USA, and Canada, and on consultations with users in the context of the Intranet Health Clinic project. More specifically, this paper has taken into account the major directives, technical reports, law, and recommendations that are related to the protection of individuals with regard to the processing of personal data, and the protection of privacy and medical data on the Internet. We present a High Level Security Policy for Health Care Establishments, which includes a set of 7 principles and 45 guidelines detailed in this paper. The proposed principles and guidelines have been made as generic and open to specific implementations as possible, to provide for maximum flexibility and adaptability to local environments. The High Level Security Policy establishes the basic security requirements that must be addressed to use the Internet to safely transmit patient and other sensitive health care information. The High Level Security Policy is primarily intended for large Health Care Establishments in Europe, USA, and Canada. It is clear however that the general framework presented here can only serve as reference material for developing an appropriate High Level Security Policy in a

  6. Editorial policy in reporting ethical processes: A survey of 'instructions for authors' in International Indexed Dental Journals.

    Science.gov (United States)

    Navaneetha, Cugati

    2011-04-01

    The International Committee of Medical Journal Editors expects authors to report if their studies were carried out in accordance with the International Ethical Guidelines and Declaration of Helsinki; and inform readers regarding the same. To determine the proportion of International Indexed Dental Journals reporting on ethical clearance for human and animal research, obtaining of informed consent and / or assent, and the conduction of research in accordance with the Declaration of Helsinki and International Medical Research, 2006. A cross-sectional survey of 'instructions for authors,' for analysis of editorial policy on ethical processes, was done. One hundred and twenty-six dental journals (which included 50 general and 76 specialties) were reviewed for reporting, with regard to the Ethical Committee Approval for human and animal researches, obtaining of informed consent / assent from the research participants, and research in accordance with the Declaration of Helsinki as well as International Medical Research 2006 were analyzed. Descriptive statistics was used and results were expressed in percentages. Of the 126 dental journals, 57 (45.23%) reported having obtained approval from the Ethics Committee, 33 (26.19%) were instructed about the Animal Ethics Committee approval, and 38 (30.15%) insisted on obtaining and reporting informed consent / assent. 41 (32.53%) journals expected authors to mention the research being conducted according to Declaration of Helsinki and and 3 (2.38%) journals required researches to be conducted in accordance with International Medical Research, 2006. A significant proportion of international indexed dental journals did not provide instructions to authors to report on the ethical approval, informed consent and / assent, and research conduction according to the Declaration of Helsinki as well as the International Medical Research, 2006.

  7. Editorial policy in reporting ethical processes: A survey of ′instructions for authors′ in International Indexed Dental Journals

    Directory of Open Access Journals (Sweden)

    Cugati Navaneetha

    2011-01-01

    Full Text Available Background: The International Committee of Medical Journal Editors expects authors to report if their studies were carried out in accordance with the International Ethical Guidelines and Declaration of Helsinki; and inform readers regarding the same. Aims: To determine the proportion of International Indexed Dental Journals reporting on ethical clearance for human and animal research, obtaining of informed consent and / or assent, and the conduction of research in accordance with the Declaration of Helsinki and International Medical Research, 2006. Settings and Design: A cross-sectional survey of ′instructions for authors,′ for analysis of editorial policy on ethical processes, was done. Materials and Methods: One hundred and twenty-six dental journals (which included 50 general and 76 specialties were reviewed for reporting, with regard to the Ethical Committee Approval for human and animal researches, obtaining of informed consent / assent from the research participants, and research in accordance with the Declaration of Helsinki as well as International Medical Research 2006 were analyzed. Statistical Analysis Used: Descriptive statistics was used and results were expressed in percentages. Results: Of the 126 dental journals, 57 (45.23% reported having obtained approval from the Ethics Committee, 33 (26.19% were instructed about the Animal Ethics Committee approval, and 38 (30.15% insisted on obtaining and reporting informed consent / assent. 41 (32.53% journals expected authors to mention the research being conducted according to Declaration of Helsinki and and 3 (2.38% journals required researches to be conducted in accordance with International Medical Research, 2006. Conclusions: A significant proportion of international indexed dental journals did not provide instructions to authors to report on the ethical approval, informed consent and / assent, and research conduction according to the Declaration of Helsinki as well as the

  8. RNA editing in plants and its evolution.

    Science.gov (United States)

    Takenaka, Mizuki; Zehrmann, Anja; Verbitskiy, Daniil; Härtel, Barbara; Brennicke, Axel

    2013-01-01

    RNA editing alters the identity of nucleotides in RNA molecules such that the information for a protein in the mRNA differs from the prediction of the genomic DNA. In chloroplasts and mitochondria of flowering plants, RNA editing changes C nucleotides to U nucleotides; in ferns and mosses, it also changes U to C. The approximately 500 editing sites in mitochondria and 40 editing sites in plastids of flowering plants are individually addressed by specific proteins, genes for which are amplified in plant species with organellar RNA editing. These proteins contain repeat elements that bind to cognate RNA sequence motifs just 5' to the edited nucleotide. In flowering plants, the site-specific proteins interact selectively with individual members of a different, smaller family of proteins. These latter proteins may be connectors between the site-specific proteins and the as yet unknown deaminating enzymatic activity.

  9. Connectivity editing for quad-dominant meshes

    KAUST Repository

    Peng, Chihan

    2013-08-01

    We propose a connectivity editing framework for quad-dominant meshes. In our framework, the user can edit the mesh connectivity to control the location, type, and number of irregular vertices (with more or fewer than four neighbors) and irregular faces (non-quads). We provide a theoretical analysis of the problem, discuss what edits are possible and impossible, and describe how to implement an editing framework that realizes all possible editing operations. In the results, we show example edits and illustrate the advantages and disadvantages of different strategies for quad-dominant mesh design. © 2013 The Author(s) Computer Graphics Forum © 2013 The Eurographics Association and John Wiley & Sons Ltd.

  10. How Philadelphia is Integrating Climate Science and Policy: Changing Capital Planning Processes and Developing Flood-Depth Tools

    Science.gov (United States)

    Bhat, C.; Dix, B.; Choate, A.; Wong, A.; Asam, S.; Schultz, P. A.

    2016-12-01

    Policy makers can implement more effective climate change adaptation programs if they are provided with two tools: accessible information on the impacts that they need to prepare for, and clear guidance on how to integrate climate change considerations into their work. This presentation will highlight recent and ongoing efforts at the City of Philadelphia to integrate climate science into their decision-making. These efforts include developing a climate change information visualization tool, climate change risk assessments across the city, and processes to integrate climate change into routine planning and budgeting practices. The goal of these efforts is to make climate change science highly targeted to decision maker needs, non-political, easily accessible, and actionable. While sea level rise inundation maps have been available to communities for years, the maps do not effectively communicate how the design of a building or a piece of infrastructure would need to be modified to protect it. The Philadelphia Flood Risk Viewer is an interactive planning tool that allows Philadelphia to identify projected depths of flooding for any location within the City, for a variety of sea level rise and storm surge scenarios. Users can also determine whether a location is located in a FEMA floodplain. By having access to information on the projected depth of flooding at a given location, the City can determine what flood protection measures may be effective, or even inform the long-term viability of developing a particular area. With an understanding of climate vulnerabilities, cities have the opportunity to make smart, climate-resilient investments with their capital budgets that will yield multiple benefits for years to come. Few, however, have established protocols for doing so. Philadelphia, with support from ICF, developed a guidance document that identifies recommendations for integrating climate change considerations throughout the Capital Program and capital budgeting

  11. Operational Transformation In Co-Operative Editing

    Directory of Open Access Journals (Sweden)

    Mandeep Kaur

    2015-08-01

    Full Text Available Cooperative Editing Systems in real-time allows a virtual team to view and edit a shared document at the same time. The document shared must be synchronized in order to ensure consistency for all the participants. This paper describes the Operational Transformation the evolution of its techniques its various applications major issues and achievements. In addition this paper will present working of a platform where two users can edit a code programming file at the same time.

  12. When and How do Bureaucratic Conflicts Matter in Trade Policy? Evidence from the US Trade Policymaking Process during the Clinton Administration (1993–2001

    Directory of Open Access Journals (Sweden)

    Rodrigo Fagundes Cézar

    Full Text Available Abstract The study of the role played by bureaucracies contributed substantively to the analysis of the domestic determinants of foreign policy outcomes, particularly by softening the premise of the state as a unitary-rational actor. However, the potential of focusing on bureaucracies to analyse US trade policy outcomes has been severely underestimated by the most recent IPE scholarship, which tends to focus on the Congress and interest groups, and to consider the Executive a unitary actor. Based on elements of the bureaucratic politics model, this article uses evidence from the US trade policy during Clinton’s administration (1993–2001 in order to present arguments regarding how and when bureaucratic conflicts matter the most, and highlight the relevance of these conflicts in the trade decision-making process.

  13. Power and Politics in the Global Health Landscape: Beliefs, Competition and Negotiation Among Global Advocacy Coalitions in the Policy-Making Process

    Directory of Open Access Journals (Sweden)

    Lori McDougall

    2016-05-01

    of advantage. Global health policy-making is an arena of contested interests, power and ideas, shaped by the interaction of coalitions. Although policy-making is often seen as a process that should be guided by evidence rather than interest-based politics, this study concludes that a participatory process of debate among different actorcoalitions is vital to progress and can lend greater legitimacy, accountability and transparency to the policy process.

  14. Power and Politics in the Global Health Landscape: Beliefs, Competition and Negotiation Among Global Advocacy Coalitions in the Policy-Making Process.

    Science.gov (United States)

    McDougall, Lori

    2016-01-30

    contested interests, power and ideas, shaped by the interaction of coalitions. Although policy-making is often seen as a process that should be guided by evidence rather than interest-based politics, this study concludes that a participatory process of debate among different actor-coalitions is vital to progress and can lend greater legitimacy, accountability and transparency to the policy process. © 2016 by Kerman University of Medical Sciences.

  15. Façade insulation retrofitting policy implementation process and its effects on health equity determinants: A realist review

    International Nuclear Information System (INIS)

    Camprubí, Lluís; Malmusi, Davide; Mehdipanah, Roshanak

    2016-01-01

    Fuel poverty and cold housing constitute a significant public health problem. Energy efficiency interventions, such as façade retrofitting, address the problem from a structural and long-term perspective. Despite evidence of the health benefits of insulation, little is known about the political and social contexts that contribute to social inequalities in receiving and experiencing health benefits from these interventions. We used a realist review methodology to better understand the mechanisms that explain how and why variations across different social groups appear in receiving energy efficiency façade retrofitting interventions and in their impact on health determinants. We considered the four stages of the policy implementation framework: public policy approach; policy; receiving intervention and impact on health determinants. We found strong evidence that certain social groups (low-income, renters, elderly) suffering most from fuel poverty, experience more barriers for undertaking a building retrofitting (due to factors such as upfront costs, “presentism” thinking, split incentives, disruption and lack of control), and that some public policies on housing energy efficiency may exacerbate these inequalities. This can be avoided if such policies specifically aim at tackling fuel poverty or social inequities, are completely free to users, target the most affected groups and are adapted to their needs. - Highlights: •Health benefits of housing façade insulation more pronounced in fuel poor groups. •Social groups suffering most from fuel poverty least likely to undergo insulation. •Energy efficiency policies focused solely on CO 2 reduction may increase inequalities. •Split Incentives and “Take-Back” effect show socioeconomic and contextual variability. •Universal policies without targeting increase inequalities in retrofitting uptake.

  16. Fuel Cell Handbook, Fourth Edition

    Energy Technology Data Exchange (ETDEWEB)

    Stauffer, D.B; Hirschenhofer, J.H.; Klett, M.G.; Engleman, R.R.

    1998-11-01

    Robust progress has been made in fuel cell technology since the previous edition of the Fuel Cell Handbook was published in January 1994. This Handbook provides a foundation in fuel cells for persons wanting a better understanding of the technology, its benefits, and the systems issues that influence its application. Trends in technology are discussed, including next-generation concepts that promise ultra high efficiency and low cost, while providing exceptionally clean power plant systems. Section 1 summarizes fuel cell progress since the last edition and includes existing power plant nameplate data. Section 2 addresses the thermodynamics of fuel cells to provide an understanding of fuel cell operation at two levels (basic and advanced). Sections 3 through 6 describe the four major fuel cell types and their performance based on cell operating conditions. The section on polymer electrolyte membrane fuel cells has been added to reflect their emergence as a significant fuel cell technology. Phosphoric acid, molten carbonate, and solid oxide fuel cell technology description sections have been updated from the previous edition. New information indicates that manufacturers have stayed with proven cell designs, focusing instead on advancing the system surrounding the fuel cell to lower life cycle costs. Section 7, Fuel Cell Systems, has been significantly revised to characterize near-term and next-generation fuel cell power plant systems at a conceptual level of detail. Section 8 provides examples of practical fuel cell system calculations. A list of fuel cell URLs is included in the Appendix. A new index assists the reader in locating specific information quickly.

  17. Case Studies in Policy Making. 11th Edition

    Science.gov (United States)

    2008-01-01

    buildup. Rather, the “hot topic” remained the Schonau incident.27 Not everyone in AMAN was as wedded to “the concept” as those at the top. On 1 October, a...His effort to allow gays to serve openly, one that he had pursued early in his first administration, started the rela- tionship off on a pretty bad

  18. From engineering to editing the rat genome.

    Science.gov (United States)

    Meek, Stephen; Mashimo, Tomoji; Burdon, Tom

    2017-08-01

    ES culture and gene editing technologies can play complementary roles in generating accurate bespoke rat models for studying biological processes and modelling human disease.

  19. A survey on the methodological processes and policies of renal guideline groups as a first step to harmonize renal guidelines.

    Science.gov (United States)

    Haller, Maria C; van der Veer, Sabine N; Nagler, Evi V; Tomson, Charlie; Lewington, Andrew; Hemmelgarn, Brenda R; Gallagher, Martin; Rocco, Michael; Obrador, Gregorio; Vanholder, Raymond; Craig, Jonathan C; van Biesen, Wim

    2015-07-01

    Worldwide, several bodies produce renal guidelines, potentially leading to duplication of effort while other topics may remain uncovered. A collaborative work plan could improve efficiency and impact, but requires a common approved methodology. The aim of this study was to identify organizational and methodological similarities and differences among seven major renal guideline bodies to identify methodological barriers to a collaborative effort. An electronic 62-item survey with questions based on the Institute of Medicine standards for guidelines was completed by representatives of seven major organizations producing renal guidelines: the Canadian Society of Nephrology (CSN), European Renal Best Practice (ERBP), Kidney Disease Improving Global Outcome (KDIGO), Kidney Health Australia-Caring for Australians with Renal Insufficiency (KHA-CARI), Kidney Disease Outcome Quality Initiative (KDOQI), Sociedad Latino-Americano de Nefrologia e Hipertension (SLANH) and United Kingdom Renal Association (UK-RA). Five of the seven groups conduct systematic searches for evidence, two include detailed critical appraisal and all use the GRADE framework. Five have public review of the guideline draft. Guidelines are updated as new evidence comes up in all, and/or after a specified time frame has passed (N = 3). Commentaries or position statements on guidelines published by other groups are produced by five, with the ADAPTE framework (N = 1) and the AGREEII (N = 2) used by some. Funding is from their parent organizations (N = 5) or directly from industry (N = 2). None allow funders to influence topic selection or guideline content. The budgets to develop a full guideline vary from $2000 to $500 000. Guideline development groups vary in size from <5 (N = 1) to 13-20 persons (N = 3). Three explicitly seek patient perspectives, for example, by involving patients in the scoping process, and four incorporate health economic considerations. All provide training in methodology for

  20. Systematic identification of edited microRNAs in the human brain

    Science.gov (United States)

    Alon, Shahar; Mor, Eyal; Vigneault, Francois; Church, George M.; Locatelli, Franco; Galeano, Federica; Gallo, Angela; Shomron, Noam; Eisenberg, Eli

    2012-01-01

    Adenosine-to-inosine (A-to-I) editing modifies RNA transcripts from their genomic blueprint. A prerequisite for this process is a double-stranded RNA (dsRNA) structure. Such dsRNAs are formed as part of the microRNA (miRNA) maturation process, and it is therefore expected that miRNAs are affected by A-to-I editing. Editing of miRNAs has the potential to add another layer of complexity to gene regulation pathways, especially if editing occurs within the miRNA–mRNA recognition site. Thus, it is of interest to study the extent of this phenomenon. Current reports in the literature disagree on its extent; while some reports claim that it may be widespread, others deem the reported events as rare. Utilizing a next-generation sequencing (NGS) approach supplemented by an extensive bioinformatic analysis, we were able to systematically identify A-to-I editing events in mature miRNAs derived from human brain tissues. Our algorithm successfully identified many of the known editing sites in mature miRNAs and revealed 17 novel human sites, 12 of which are in the recognition sites of the miRNAs. We confirmed most of the editing events using in vitro ADAR overexpression assays. The editing efficiency of most sites identified is very low. Similar results are obtained for publicly available data sets of mouse brain-regions tissues. Thus, we find that A-to-I editing does alter several miRNAs, but it is not widespread. PMID:22499667

  1. RCC-MX (2008 edition)

    International Nuclear Information System (INIS)

    Bravo, X.; Drubay, B.

    2008-10-01

    The RCC-MX books is a compilation of design and construction rules for the mechanical materials of experimental reactors, for their auxiliaries and irradiation devices. This second edition includes the updates of references to NF, EN and ISO standards, the compliance with the regulations for nuclear pressure equipments, and the feedback since the 2005 edition. It comprises 9 books and a CD-Rom and includes a presentation document. The RCC-MX has been developed for the Jules Horowitz reactor but can be used for the design and construction of new projects of new experimental reactors or new equipments and devices for existing facilities. Content: - Book 1: general dispositions, materials for experimental reactors and their auxiliaries, for irradiation devices and for control or handling mechanisms, complementary requirements and particular dispositions; - Book 2: materials for the reactor and for its level 1 auxiliaries; - Book 3: materials for the reactor and for its level 2 and level 3 auxiliaries, control and handling mechanisms, materials for irradiation devices; - Book 4: technical appendixes - materials characteristics (steels and alloys); - Book 5: technical appendixes (design rules); - Book 6: technical specifications of materials; - Book 7: tests and control methods; - Book 8: welding; - Book 9: fabrication. (J.S.)

  2. Glycine receptors caught between genome and proteome - functional implications of RNA editing and splicing

    Directory of Open Access Journals (Sweden)

    Pascal Legendre

    2009-11-01

    Full Text Available Information processing in the brain requires a delicate balance between excitation and inhibition. Glycine receptors (GlyR are involved in inhibitory mechanisms mainly at a synaptic level, but potential novel roles for these receptors recently emerged due to the discovery of posttranscriptional processing. GLR transcripts are edited through enzymatic modification of a single nucleotide leading to amino acid substitution within the neurotransmitter binding domain. RNA editing produces gain-of-function receptors well suited for generation and maintenance of tonic inhibition of neuronal excitability. As neuronal activity deprivation in early stages of development or in epileptic tissue is detrimental to neurons and because RNA editing of GlyR is up-regulated in temporal lobe epilepsy patients with a severe course of disease a pathophysiological role of these receptors emerges. This review contains a state-of-the-art discussion of (pathophysiological implications of GlyR RNA editing.

  3. TALEN-mediated genome editing: prospects and perspectives

    Energy Technology Data Exchange (ETDEWEB)

    Wright, DA; Li, T; Yang, B; Spalding, MH

    2014-08-15

    Genome editing is the practice of making predetermined and precise changes to a genome by controlling the location of DNA DSBs (double-strand breaks) and manipulating the cell's repair mechanisms. This technology results from harnessing natural processes that have taken decades and multiple lines of inquiry to understand. Through many false starts and iterative technology advances, the goal of genome editing is just now falling under the control of human hands as a routine and broadly applicable method. The present review attempts to define the technique and capture the discovery process while following its evolution from meganucleases and zinc finger nucleases to the current state of the art: TALEN (transcription-activator-like effector nuclease) technology. We also discuss factors that influence success, technical challenges, and future prospects of this quickly evolving area of study and application.

  4. Social acceptability of climate change policies; will energy efficiency always fail to win its case through the consultation process? Volume 1

    International Nuclear Information System (INIS)

    Pett, Jacky

    2007-01-01

    Which segments of society 'win' as a result of climate change policies? Actors generally support the principle of reduced emissions through decarbonising fuels, and many are convinced that reducing overall energy consumption is an essential strategy to prevent further damaging climate change. However, proposed strategies for ensuring that sufficient action is taken to reduce emissions suffer from complexity, uncertainty and dissent, especially from vested interests. The policy maker has to choose between many options, and many conflicting consultation responses, to select the most politically feasible and socially acceptable pathway. An FP6 funded project into Adaptation and Mitigation Strategies for climate change is developing an innovative tool to support policy choice based on a mix of methods, using case studies to test the outputs. Resources include stakeholder deliberation on criteria necessary to evaluate pathway options. The first stage maps energy actors' perspectives of climate change, identifying key issues for socially acceptable policies for the 2012 - 2050 period that would either limit climate change to only 2 deg C increase, or provide a 'soft landing' to a world 5 degrees above present.This paper describes this mapping exercise and indicates the issues of most debate, on which rest the criteria for social acceptability. It describes how deliberative methods can involve stakeholders more effectively in policy formation, contrasts the roles of deliberation and consultation, and discusses the engagement of powerful vested interests with this approach. While there are considerable overlaps in perspectives of different actors, leading to specific points of contention, importantly, decisions on selection and engagement of stakeholders with the process become critical if the criteria for policy decisions are to be accepted by society

  5. Bibliography of Fynbos ecology: 2nd edition

    CSIR Research Space (South Africa)

    Manders, PT

    1989-12-01

    Full Text Available The first edition of a bibliography of fynbos ecology was produced in 1981 and comprised 814 references to work completed or commenced prior to the initiation of the Fynbos Biome Project. It is appropriate that this second edition...

  6. The Technique of Editing 16mm. Films.

    Science.gov (United States)

    Burder, John

    For professionals and advanced amateurs, this book covers all aspects of editing 16 millimeter film. Beginning with basic matters of film gauge, equipment, and editing facilities, it covers the mechanics of the subject using a how-to-do-it approach. The techniques discussed include preparation of the sound track, cutting, mixing, choice of pace…

  7. Site-specific photochemical RNA editing.

    Science.gov (United States)

    Fujimoto, Kenzo; Konishi-Hiratsuka, Kaoru; Sakamoto, Takashi; Yoshimura, Yoshinaga

    2010-10-28

    Photo-induced artificial RNA editing was demonstrated using photo-reactive oligonucleotides containing 3-cyanovinylcarbazole nucleoside. This non-enzymatic and sequence-specific methodology will make a major contribution to the elucidation of RNA functions including non-coding RNAs and to the development of drugs based on sequence-specific RNA editing.

  8. The Aldine Edition of Aristotle's De Sensu

    DEFF Research Database (Denmark)

    Bloch, David Kristian

    2006-01-01

    This small article examines the quality of and the textual foundation for the først printed edition ever of Aristotle's De Sensu et Sensibilibus, that is, Aldus Manutius' (1497).......This small article examines the quality of and the textual foundation for the først printed edition ever of Aristotle's De Sensu et Sensibilibus, that is, Aldus Manutius' (1497)....

  9. Sex Differences in Cognitive Abilities. Fourth Edition

    Science.gov (United States)

    Halpern, Diane F.

    2011-01-01

    The fourth edition of "Sex Differences in Cognitive Abilities" critically examines the breadth of research on this complex and controversial topic, with the principal aim of helping the reader to understand where sex differences are found--and where they are not. Since the publication of the third edition, there have been many exciting and…

  10. Framing in policy processes: a case study from hospital planning in the National Health Service in England.

    Science.gov (United States)

    Jones, Lorelei; Exworthy, Mark

    2015-01-01

    This paper reports from an ethnographic study of hospital planning in England undertaken between 2006 and 2009. We explored how a policy to centralise hospital services was espoused in national policy documents, how this shifted over time and how it was translated in practice. We found that policy texts defined hospital planning as a clinical issue and framed decisions to close hospitals or hospital departments as based on the evidence and necessary to ensure safety. We interpreted this framing as a rhetorical strategy for implementing organisational change in the context of community resistance to service closure and a concomitant policy emphasising the importance of public and patient involvement in planning. Although the persuasive power of the framing was limited, a more insidious form of power was identified in the way the framing disguised the political nature of the issue by defining it as a clinical problem. We conclude by discussing how the clinical rationale constrains public participation in decisions about the delivery and organisation of healthcare and restricts the extent to which alternative courses of action can be considered. Copyright © 2014 Elsevier Ltd. All rights reserved.

  11. Therapeutic Genome Editing and its Potential Enhancement through CRISPR Guide RNA and Cas9 Modifications.

    Science.gov (United States)

    Batzir, Nurit Assia; Tovin, Adi; Hendel, Ayal

    2017-06-01

    Genome editing with engineered nucleases is a rapidly growing field thanks to transformative technologies that allow researchers to precisely alter genomes for numerous applications including basic research, biotechnology, and human gene therapy. The genome editing process relies on creating a site-specific DNA double-strand break (DSB) by engineered nucleases and then allowing the cell's repair machinery to repair the break such that precise changes are made to the DNA sequence. The recent development of CRISPR-Cas systems as easily accessible and programmable tools for genome editing accelerates the progress towards using genome editing as a new approach to human therapeutics. Here we review how genome editing using engineered nucleases works and how using different genome editing outcomes can be used as a tool set for treating human diseases. We then review the major challenges of therapeutic genome editing and we discuss how its potential enhancement through CRISPR guide RNA and Cas9 protein modifications could resolve some of these challenges. Copyright© of YS Medical Media ltd.

  12. Journal of Special Operations Medicine, Volume 7, Edition 1

    Science.gov (United States)

    2007-01-01

    Hypertensive vascular disease Chp 246 Harrison’s Principles of Internal Medicine 15th edition McGraw Hill. 4. American Heart Association, Statistical...submit articles that deal with trauma, orthopedic injuries, infectious disease processes, and/or en- vironment and wilderness medicine. More than...by chronicling the formation and evolution of Special Operations medicine. Special Operations units are truly that – spe- cial, and their medical care

  13. Design and safety features of commercial nuclear power plants in Japan, 1976 edition

    International Nuclear Information System (INIS)

    Izumi, Fumio; Harayama, Yasuo

    1976-10-01

    The December 1975 edition (JAERI-M 5959) contained design particulars and safety features of 20 commercial nuclear power plants in Japan as of December 1974. Subsequently new plants have been put into operation and some plants under construction have undergone design modifications. The present edition presents similar data of the commercial nuclear power plants in Japan up to June 1976, compiled by computer processing. (auth.)

  14. Extended Edited Synoptic Cloud Reports from Ships and Land Stations Over the Globe, 1952-1996

    Energy Technology Data Exchange (ETDEWEB)

    Hahn, C.J.; Warren, S.G.

    1999-08-01

    Surface synoptic weather reports for the entire globe, gathered from various available data sets, were processed, edited, and rewritten to provide a single data set of individual observations of clouds, spanning the 44 years 1952-1995 for ship data and the 26 years 1971-1996 for land station data. In addition to the cloud portion of the synoptic report, each edited report also includes the associated pressure, present weather, wind, air temperature, and dew point (and sea surface temperature over oceans).

  15. A review of the progress and pitfalls of FDA policy process: Planning a pathway for pharmaceutical interventions for hearing loss development.

    Science.gov (United States)

    Hammill, Tanisha L

    2017-06-01

    The Federal Food and Drug Administration, or FDA is generally considered a powerful gatekeeper, able to deliver or withhold life-saving cures and create or destroy economic windfalls. As the decades go by, and technologies, diseases, public health demands, and politics evolve, we can identify patterns of change, action and inter-action among some of these traditional stakeholders in the FDA's policy sphere. A careful examination of this agency's colorful history can shed light on central features of the agency's policy process, which has been quite receptive to its stakeholders and adaptive to change over the decades and, in turn, show the way for development in lanes which do not fit neatly into the current paradigms offered by the agency. This paper will explore the history of FDA policy process, through examination of seminal moments in FDA history, the prominent actors and focusing events within them, and the outcomes of those events, in an attempt to illuminate a pattern of behavior or processes by which a struggling field of pharmaceutical development such as interventions for hearing loss can advance. Copyright © 2016 Elsevier B.V. All rights reserved.

  16. CRISPR-Cas9-Edited Site Sequencing (CRES-Seq): An Efficient and High-Throughput Method for the Selection of CRISPR-Cas9-Edited Clones.

    Science.gov (United States)

    Veeranagouda, Yaligara; Debono-Lagneaux, Delphine; Fournet, Hamida; Thill, Gilbert; Didier, Michel

    2018-01-16

    The emergence of clustered regularly interspaced short palindromic repeats-Cas9 (CRISPR-Cas9) gene editing systems has enabled the creation of specific mutants at low cost, in a short time and with high efficiency, in eukaryotic cells. Since a CRISPR-Cas9 system typically creates an array of mutations in targeted sites, a successful gene editing project requires careful selection of edited clones. This process can be very challenging, especially when working with multiallelic genes and/or polyploid cells (such as cancer and plants cells). Here we described a next-generation sequencing method called CRISPR-Cas9 Edited Site Sequencing (CRES-Seq) for the efficient and high-throughput screening of CRISPR-Cas9-edited clones. CRES-Seq facilitates the precise genotyping up to 96 CRISPR-Cas9-edited sites (CRES) in a single MiniSeq (Illumina) run with an approximate sequencing cost of $6/clone. CRES-Seq is particularly useful when multiple genes are simultaneously targeted by CRISPR-Cas9, and also for screening of clones generated from multiallelic genes/polyploid cells. © 2018 by John Wiley & Sons, Inc. Copyright © 2018 John Wiley & Sons, Inc.

  17. Fuel Cell Handbook, Fifth Edition

    Energy Technology Data Exchange (ETDEWEB)

    Energy and Environmental Solutions

    2000-10-31

    Progress continues in fuel cell technology since the previous edition of the Fuel Cell Handbook was published in November 1998. Uppermost, polymer electrolyte fuel cells, molten carbonate fuel cells, and solid oxide fuel cells have been demonstrated at commercial size in power plants. The previously demonstrated phosphoric acid fuel cells have entered the marketplace with more than 220 power plants delivered. Highlighting this commercial entry, the phosphoric acid power plant fleet has demonstrated 95+% availability and several units have passed 40,000 hours of operation. One unit has operated over 49,000 hours. Early expectations of very low emissions and relatively high efficiencies have been met in power plants with each type of fuel cell. Fuel flexibility has been demonstrated using natural gas, propane, landfill gas, anaerobic digester gas, military logistic fuels, and coal gas, greatly expanding market opportunities. Transportation markets worldwide have shown remarkable interest in fuel cells; nearly every major vehicle manufacturer in the U.S., Europe, and the Far East is supporting development. This Handbook provides a foundation in fuel cells for persons wanting a better understanding of the technology, its benefits, and the systems issues that influence its application. Trends in technology are discussed, including next-generation concepts that promise ultrahigh efficiency and low cost, while providing exceptionally clean power plant systems. Section 1 summarizes fuel cell progress since the last edition and includes existing power plant nameplate data. Section 2 addresses the thermodynamics of fuel cells to provide an understanding of fuel cell operation at two levels (basic and advanced). Sections 3 through 8 describe the six major fuel cell types and their performance based on cell operating conditions. Alkaline and intermediate solid state fuel cells were added to this edition of the Handbook. New information indicates that manufacturers have stayed

  18. The Raison d'Être of Mutual Recognition: An Analysis of the 2015 Reform to Research Ethics Review Policies, Processes and Problems in Québec

    Directory of Open Access Journals (Sweden)

    Vasiliki Rahimzadeh

    2017-11-01

    Full Text Available Ethics review is a pre-requisite to conducting research involving humans in Canada, and indeed in most international jurisdictions. The Tri-Council Policy Statement on Ethical Conduct for Research Involving Humans (TCPS2 serves as the national policy framework for research ethics review in Canada, and outlines three potential oversight models: independent, delegated and reciprocal. While the independent model preserves institutional oversight of research, it contributes to a duplicative system that can unduly delay research and impose barriers to research collaboration. This analysis centres on a 2015 reform to the policy model of research ethics review for collaborative, multi-site studies in the province of Québec. Informal interviews with key informants supplemented a document analysis of provincial research ethics policies using the comparative framework proposed by Lavis and colleagues. Consolidating bureaucratic structures and preserving locally-relevant review studies that span multiple sites remain among the most pressing challenges to transitioning from an independent model, and could provide reference for other provinces that have, or are currently in the process of such a transition.

  19. Evaluating the Process and Extent of Institutionalization: A Case Study of a Rapid Response Unit for Health Policy in Burkina Faso

    Directory of Open Access Journals (Sweden)

    Andre Zida

    2018-01-01

    Full Text Available Background Good decision-making requires gathering and using sufficient information. Several knowledge translation platforms have been introduced in Burkina Faso to support evidence-informed decision-making. One of these is the rapid response service for health. This platform aims to provide quick access for policy-makers in Burkina Faso to highquality research evidence about health systems. The purpose of this study is to describe the process and extent of the institutionalization of the rapid response service. Methods A qualitative case study design was used, drawing on interviews with policy-makers, together with documentary analysis. Previously used institutionalization frameworks were combined to guide the analysis. Results Burkina Faso’s rapid response service has largely reached the consolidation phase of the institutionalization process but not yet the final phase of maturity. The impetus for the project came from designated project leaders, who convinced policy-makers of the importance of the rapid response service, and obtained resources to run a pilot. During the expansion stage, additional policy-makers at national and sub-national levels began to use the service. Unit staff also tried to improve the way it was delivered, based on lessons learned during the pilot stage. The service has, however, stagnated at the consolidation stage, and not moved into the final phase of maturity. Conclusion The institutionalization process for the rapid response service in Burkina Faso has been fluid rather than linear, with some areas developing faster than others. The service has reached the consolidation stage, but now requires additional efforts to reach maturity.

  20. Evaluating the Process and Extent of Institutionalization: A Case Study of a Rapid Response Unit for Health Policy in Burkina Faso.

    Science.gov (United States)

    Zida, Andre; Lavis, John N; Sewankambo, Nelson K; Kouyate, Bocar; Ouedraogo, Salimata

    2017-04-10

    Good decision-making requires gathering and using sufficient information. Several knowledge translation platforms have been introduced in Burkina Faso to support evidence-informed decision-making. One of these is the rapid response service for health. This platform aims to provide quick access for policy-makers in Burkina Faso to highquality research evidence about health systems. The purpose of this study is to describe the process and extent of the institutionalization of the rapid response service. A qualitative case study design was used, drawing on interviews with policy-makers, together with documentary analysis. Previously used institutionalization frameworks were combined to guide the analysis. Burkina Faso's rapid response service has largely reached the consolidation phase of the institutionalization process but not yet the final phase of maturity. The impetus for the project came from designated project leaders, who convinced policy-makers of the importance of the rapid response service, and obtained resources to run a pilot. During the expansion stage, additional policy-makers at national and sub-national levels began to use the service. Unit staff also tried to improve the way it was delivered, based on lessons learned during the pilot stage. The service has, however, stagnated at the consolidation stage, and not moved into the final phase of maturity. The institutionalization process for the rapid response service in Burkina Faso has been fluid rather than linear, with some areas developing faster than others. The service has reached the consolidation stage, but now requires additional efforts to reach maturity. © 2018 The Author(s); Published by Kerman University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly

  1. сисOptimization of the state information policy of Ukraine in the conditions of contemporary modernization processes

    Directory of Open Access Journals (Sweden)

    E. O. Romanenko

    2014-10-01

    Today in Ukraine is a strategic document that at the national level to govern the main priorities, directions, principles, principles and ways of realization of the State policy on implementing its information and communication functions. Moreover the communicative component state is not clearly separated from the information, and therefore does not have the proper conceptual, technological and functional software, also destablzacjno affects the livelihoods of its public sector.

  2. Relating Actor Analysis Methods to Policy Problems

    NARCIS (Netherlands)

    Van der Lei, T.E.

    2009-01-01

    For a policy analyst the policy problem is the starting point for the policy analysis process. During this process the policy analyst structures the policy problem and makes a choice for an appropriate set of methods or techniques to analyze the problem (Goeller 1984). The methods of the policy

  3. Ensuring due process in the IACUC and animal welfare setting: considerations in developing noncompliance policies and procedures for institutional animal care and use committees and institutional officials.

    Science.gov (United States)

    Hansen, Barbara C; Gografe, Sylvia; Pritt, Stacy; Jen, Kai-Lin Catherine; McWhirter, Camille A; Barman, Susan M; Comuzzie, Anthony; Greene, Molly; McNulty, Justin A; Michele, Daniel Eugene; Moaddab, Naz; Nelson, Randall J; Norris, Karen; Uray, Karen D; Banks, Ron; Westlund, Karin N; Yates, Bill J; Silverman, Jerald; Hansen, Kenneth D; Redman, Barbara

    2017-10-01

    Every institution that is involved in research with animals is expected to have in place policies and procedures for the management of allegations of noncompliance with the Animal Welfare Act and the U.S. Public Health Service Policy on the Humane Care and Use of Laboratory Animals. We present here a model set of recommendations for institutional animal care and use committees and institutional officials to ensure appropriate consideration of allegations of noncompliance with federal Animal Welfare Act regulations that carry a significant risk or specific threat to animal welfare. This guidance has 3 overarching aims: 1 ) protecting the welfare of research animals; 2 ) according fair treatment and due process to an individual accused of noncompliance; and 3 ) ensuring compliance with federal regulations. Through this guidance, the present work seeks to advance the cause of scientific integrity, animal welfare, and the public trust while recognizing and supporting the critical importance of animal research for the betterment of the health of both humans and animals.-Hansen, B. C., Gografe, S., Pritt, S., Jen, K.-L. C., McWhirter, C. A., Barman, S. M., Comuzzie, A., Greene, M., McNulty, J. A., Michele, D. E., Moaddab, N., Nelson, R. J., Norris, K., Uray, K. D., Banks, R., Westlund, K. N., Yates, B. J., Silverman, J., Hansen, K. D., Redman, B. Ensuring due process in the IACUC and animal welfare setting: considerations in developing noncompliance policies and procedures for institutional animal care and use committees and institutional officials. © FASEB.

  4. Genome edited animals: Learning from GM crops?

    Science.gov (United States)

    Bruce, Ann

    2017-06-01

    Genome editing of livestock is poised to become commercial reality, yet questions remain as to appropriate regulation, potential impact on the industry sector and public acceptability of products. This paper looks at how genome editing of livestock has attempted to learn some of the lessons from commercialisation of GM crops, and takes a systemic approach to explore some of the complexity and ambiguity in incorporating genome edited animals in a food production system. Current applications of genome editing are considered, viewed from the perspective of past technological applications. The question of what is genome editing, and can it be considered natural is examined. The implications of regulation on development of different sectors of livestock production systems are studied, with a particular focus on the veterinary sector. From an EU perspective, regulation of genome edited animals, although not necessarily the same as for GM crops, is advocated from a number of different perspectives. This paper aims to open up new avenues of research on genome edited animals, extending from the current primary focus on science and regulation, to engage with a wider-range of food system actors.

  5. MP3 audio-editing software for the department of radiology

    International Nuclear Information System (INIS)

    Hong Qingfen; Sun Canhui; Li Ziping; Meng Quanfei; Jiang Li

    2006-01-01

    Objective: To evaluate the MP3 audio-editing software in the daily work in the department of radiology. Methods: The audio content of daily consultation seminar, held in the department of radiology every morning, was recorded and converted into MP3 audio format by a computer integrated recording device. The audio data were edited, archived, and eventually saved in the computer memory storage media, which was experimentally replayed and applied in the research or teaching. Results: MP3 audio-editing was a simple process and convenient for saving and searching the data. The record could be easily replayed. Conclusion: MP3 audio-editing perfectly records and saves the contents of consultation seminar, and has replaced the conventional hand writing notes. It is a valuable tool in both research and teaching in the department. (authors)

  6. Regulation of gene expression and RNA editing in Drosophila adapting to divergent microclimates.

    Science.gov (United States)

    Yablonovitch, Arielle L; Fu, Jeremy; Li, Kexin; Mahato, Simpla; Kang, Lin; Rashkovetsky, Eugenia; Korol, Abraham B; Tang, Hua; Michalak, Pawel; Zelhof, Andrew C; Nevo, Eviatar; Li, Jin Billy

    2017-11-17

    Determining the mechanisms by which a species adapts to its environment is a key endeavor in the study of evolution. In particular, relatively little is known about how transcriptional processes are fine-tuned to adjust to different environmental conditions. Here we study Drosophila melanogaster from 'Evolution Canyon' in Israel, which consists of two opposing slopes with divergent microclimates. We identify several hundred differentially expressed genes and dozens of differentially edited sites between flies from each slope, correlate these changes with genetic differences, and use CRISPR mutagenesis to validate that an intronic SNP in prominin regulates its editing levels. We also demonstrate that while temperature affects editing levels at more sites than genetic differences, genetically regulated sites tend to be less affected by temperature. This work shows the extent to which gene expression and RNA editing differ between flies from different microclimates, and provides insights into the regulation responsible for these differences.

  7. A-to-I editing of coding and non-coding RNAs by ADARs

    Science.gov (United States)

    Nishikura, Kazuko

    2016-01-01

    Adenosine deaminases acting on RNA (ADARs) convert adenosine to inosine in double-stranded RNA. This A-to-I editing occurs not only in protein-coding regions of mRNAs, but also frequently in non-coding regions that contain inverted Alu repeats. Editing of coding sequences can result in the expression of functionally altered proteins that are not encoded in the genome, whereas the significance of Alu editing remains largely unknown. Certain microRNA (miRNA) precursors are also edited, leading to reduced expression or altered function of mature miRNAs. Conversely, recent studies indicate that ADAR1 forms a complex with Dicer to promote miRNA processing, revealing a new function of ADAR1 in the regulation of RNA interference. PMID:26648264

  8. Genome-editing technologies and patent landscape overview.

    Science.gov (United States)

    Benahmed-Miniuk, Fairouz; Kresz, Mat; Kanaujiya, Jitendra K; Southgate, Christopher D

    2017-05-01

    Unlike with zinc finger nuclease and transcriptional activator-like effector nuclease DNA modification technologies that rely on lead proteins, developed through expensive and time-consuming processes, the clustered regularly interspaced short palindromic repeat (CRISPR)/Cas system has rapidly emerged as the most promising gene-editing technology to date for the modification of any selected DNA sequence. CRISPR is receiving tremendous fanfare due, in part, to its potential to provide a means to fundamentally alter medical genetics and especially cancer medicine. In this review, we compare key technologies of genome-editing zinc finger nucleases, transcriptional activator-like effector nucleases and CRISPR, with a focus on the race to acquire lucrative intellectual property rights, the current CRISPR patent dispute and potential repercussions on innovation and the adoption of this promising technology by the medical community.

  9. CRISPR-Cas9 Toolkit for Actinomycete Genome Editing

    DEFF Research Database (Denmark)

    Tong, Yaojun; Robertsen, Helene Lunde; Blin, Kai

    2018-01-01

    engineering approaches for boosting known and discovering novel natural products. In order to facilitate the genome editing for actinomycetes, we developed a CRISPR-Cas9 toolkit with high efficiency for actinomyces genome editing. This basic toolkit includes a software for spacer (sgRNA) identification......, a system for in-frame gene/gene cluster knockout, a system for gene loss-of-function study, a system for generating a random size deletion library, and a system for gene knockdown. For the latter, a uracil-specific excision reagent (USER) cloning technology was adapted to simplify the CRISPR vector...... construction process. The application of this toolkit was successfully demonstrated by perturbation of genomes of Streptomyces coelicolor A3(2) and Streptomyces collinus Tü 365. The CRISPR-Cas9 toolkit and related protocol described here can be widely used for metabolic engineering of actinomycetes....

  10. Genome Editing During Development Using the CRISPR-Cas Technology.

    Science.gov (United States)

    Arzate-Mejía, Rodrigo G; Licona-Limón, Paula; Recillas-Targa, Félix

    2018-01-01

    Over the years, the study of gene function during development involved the implementation of sophisticated transgenic strategies to visualize how organisms change during their lifetime. These strategies are diverse and extremely useful and allowed the discovery of some of the fundamental mechanisms governing organism's development. Such strategies can be time-consuming, in some cases expensive, and require complex infrastructure. With the advent of the genome editing CRISPR-Cas9 RNA-guided DNA endonuclease system a tremendous progress has been achieved in manipulating diverse organisms and cell types. In recent years this system has contributed importantly to the design of novel experimental strategies to further understand developmental processes, to generate genetically modified animal models, and develop disease models. Here we highlight examples in which the genome editing CRISPR-Cas9 system has been employed to understand the mechanisms controlling embryonic development and disease.

  11. The image processing handbook

    CERN Document Server

    Russ, John C

    2006-01-01

    Now in its fifth edition, John C. Russ's monumental image processing reference is an even more complete, modern, and hands-on tool than ever before. The Image Processing Handbook, Fifth Edition is fully updated and expanded to reflect the latest developments in the field. Written by an expert with unequalled experience and authority, it offers clear guidance on how to create, select, and use the most appropriate algorithms for a specific application. What's new in the Fifth Edition? ·       A new chapter on the human visual process that explains which visual cues elicit a response from the vie

  12. Open Access Policy for CERN Physics Publications

    CERN Document Server

    2014-01-01

    CERN is committed to Open Access. It represents one of the values written in our Convention sixty years ago and is increasingly important for our Member States.   In the last edition of the Bulletin, this article described how CERN is doing with regards to open access publishing today. On Thursday this week, the Open Access Policy for CERN Physics Publications* was endorsed by the Scientific Information Policy Board (SIPB) and approved by the Director-General the same day . For any clarifications regarding the policy, please contact the Scientific Information Service library.desk@cern.ch. * A French version of the policy will be made available shortly.

  13. Key figures on climate France, Europe and Worldwide. Edition 2018

    International Nuclear Information System (INIS)

    Baude, Manuel; Dussud, Francois-Xavier; Ecoiffier, Mathieu; Moreau, Sylvain; Bottin, Anne; Duvernoy, Jerome; Vailles, Charlotte

    2017-10-01

    In line with previous years, the 2018 edition of 'Key figures on climate' has been written in the context of the 22. Conference of the Parties on Climate Change (COP 22) held in Bonn from 6 to 17 November 2017. This latest version was updated relative to the 2017 edition. New data sources have been used for emissions factors and the part on the carbon footprint was further developed. The part on climate policies notably deals with the Paris Agreement adopted in December 2015 at COP 21. Several data sets, displayed in graphs in this document are also available in tables on the web version. Content: 1 - What is climate change? This part summarizes the scientific basis of climate change, including indicators, causes and possible consequences of global warming. 2 - Which amounts of greenhouse gases are emitted globally? The focus here is on the most relevant data related to global greenhouse gases (GHG) emissions, in particular the geographic distribution of these emissions. 3 - How much greenhouse gas is emitted in Europe and in France? A complete overview of GHG emissions statistics in Europe and in France is presented in this part as well as estimates of the carbon footprint of French people. 4 - What is the sectoral distribution of GHG emissions in Europe and in France? This part features the detailed evolution since 1990 of GHG emissions in the following economic sectors: energy sector, transports, industry, residential and tertiary, agriculture, forestry, land use and waste management. 5 - Which climate policies in the world, in Europe and in France? The main climate policies are described at each level: global, European and French

  14. Key figures on climate France and Worldwide - 2017 Edition

    International Nuclear Information System (INIS)

    Baude, Manuel; Dussud, Francois-Xavier; Ecoiffier, Mathieu; Duvernoy, Jerome; Vailles, Charlotte; Moreau, Sylvain; Bottin, Anne; Hiblot, Guillaume

    2016-10-01

    In line with previous years, the 2017 edition of 'Key figures on climate' has been written in the context of the 22. Conference of the Parties on Climate Change (COP 22) held in Marrakech from 7 to 18 November 2016. This latest version, published as part of the new 'datalab' collection of the General commission for sustainable development was updated and expanded relative to the 2016 edition. New data sources have been used for the part on global CO 2 emissions. The part on climate policies was further developed, and notably deals with the Paris agreement adopted in December 2015 at COP 21. Moreover, the analysis of climate finance (current climate investments and climate finance needs) has been expanded. About the form, and with a goal of simplification, some data previously displayed in both a graph and a table is now presented only in a graph. Content: Part 1: What is climate change? This part summarizes the scientific basis of climate change, including indicators, causes and possible consequences of global warming. Part 2: Which amounts of greenhouse gases are emitted globally? The focus here is on the most relevant data related to global greenhouse gases (GHG) emissions, in particular the geographic distribution of these emissions. Part 3: How much greenhouse gas is emitted in Europe and in France? A complete overview of GHG emissions statistics in Europe and in France is presented in this part as well as estimates of the carbon footprint of French people. Part 4: What is the sectoral distribution of GHG emissions in Europe and in France? This part features the detailed evolution since 1990 of GHG emissions in the following economic sectors: energy sector, transports, industry, residential and tertiary, agriculture, forestry, land use and waste management. Part 5: Which climate policies in the world, in Europe and in France? The main climate policies are described at each level: global, European and French

  15. KWIC Index of nuclear codes (1975 edition)

    International Nuclear Information System (INIS)

    Akanuma, Makoto; Hirakawa, Takashi

    1976-01-01

    It is a KWIC Index for 254 nuclear codes in the Nuclear Code Abstracts (1975 edition). The classification of nuclear codes and the form of index are the same as those in the Computer Programme Library at Ispra, Italy. (auth.)

  16. Specification Editing and Discovery Assistant Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The project will prototype a specification editing and discovery tool (SPEEDY) for C/C++ that will assist software developers with modular formal verification tasks...

  17. A genome editing primer for the hematologist

    Science.gov (United States)

    Hoban, Megan D.

    2016-01-01

    Gene editing enables the site-specific modification of the genome. These technologies have rapidly advanced such that they have entered common use in experimental hematology to investigate genetic function. In addition, genome editing is becoming increasingly plausible as a treatment modality to rectify genetic blood disorders and improve cellular therapies. Genome modification typically ensues from site-specific double-strand breaks and may result in a myriad of outcomes. Even single-strand nicks and targeted biochemical modifications that do not permanently alter the DNA sequence (epigenome editing) may be powerful instruments. In this review, we examine the various technologies, describe their advantages and shortcomings for engendering useful genetic alterations, and consider future prospects for genome editing to impact hematology. PMID:27053532

  18. LabVIEW 8 student edition

    CERN Document Server

    Bishop, Robert H

    2007-01-01

    For courses in Measurement and Instrumentation, Electrical Engineering lab, and Physics and Chemistry lab. This revised printing has been updated to include new LabVIEW 8.2 Student Edition. National Instruments' LabVIEW is the defacto industry standard for test, measurement, and automation software solutions. With the Student Edition of LabVIEW, students can design graphical programming solutions to their classroom problems and laboratory experiments with software that delivers the graphical programming capabilites of the LabVIEW professional version. . The Student Edition is also compatible with all National Instruments data acquisition and instrument control hardware. Note: The LabVIEW Student Edition is available to students, faculty, and staff for personal educational use only. It is not intended for research, institutional, or commercial use. For more information about these licensing options, please visit the National Instruments website at (http:www.ni.com/academic/)

  19. TRANSFORMATION THE ROLE OF THINK TANKS IN THE PROCESS OF GOVERNMENT POLICY FORMATION IN THE CONTEXT OF WORLD FINANCIAL CRISIS IN 2008-2010

    Directory of Open Access Journals (Sweden)

    Barsukov Anton Yuryevich

    2013-04-01

    Full Text Available The study is dedicated to the evolution of think tanks role as a political tool of government policy formation in the context of world financial crisis. The main purpose of the study was the description of such evolution, revealing of the basic differences with the analytical centers, founded before 2008 in China, and finding-out of think tank’ role in the process of anticrisis campaign. The actuality of the study is obvious, proceeding from there are not any other study dedicated to the Chinese “new type” think tanks in Russian politologycal science. The appearance of “new type” think tanks in the PRC is mentioned in the study. The special meaning devoted to the increasing of returnees’ role in the process of government policy formation. The author makes the conclusion that “new type” think tanks have a very important meaning just as in the process of anticrisis campaign so in the public life. “New type” think tanks have more independence from the official authorities.

  20. TRANSFORMATION THE ROLE OF THINK TANKS IN THE PROCESS OF GOVERNMENT POLICY FORMATION IN THE CONTEXT OF WORLD FINANCIAL CRISIS IN 2008-2010

    Directory of Open Access Journals (Sweden)

    Антон Юрьевич Барсуков

    2013-05-01

    Full Text Available The study is dedicated to the evolution of think tanks role as a political tool of government policy formation in the context of world financial crisis. The main purpose of the study was the description of such evolution, revealing of the basic differences with the analytical centers, founded before 2008 in China, and finding-out of think tank’ role in the process of anticrisis campaign.The actuality of the study is obvious, proceeding from there are not any other study dedicated to the Chinese “new type” think tanks in Russian politologycal science.The appearance of “new type” think tanks in the PRC is mentioned in the study. The special meaning devoted to the increasing of returnees’ role in the process of government policy formation. The author makes the conclusion that “new type” think tanks have a very important meaning just as in the process of anticrisis campaign so in the public life. “New type” think tanks have more independence from the official authorities. DOI: http://dx.doi.org/10.12731/2218-7405-2013-4-38

  1. Ambiguously Divided Responsibilities across Government Spheres: How they Impact the Policy Process and Result in Coordination Problems in the Case of Poland

    Directory of Open Access Journals (Sweden)

    Hans Dubois

    2014-07-01

    Full Text Available Empirical studies in decentralized settings associate ambiguities in the division of responsibilities between government spheres with coordination problems. This study explores the mechanisms behind this association, mainly drawing on in-depth interviews with local government officials in Poland. A typology emerges from the data. Ambiguities can refer to the policy content, but also to the rationale behind responsibilities. They may be real or perceived. The agent who perceives the ambiguities can be close to public administration (internal or further removed from it (external. External ambiguities mostly inhibit front-room stages of the policy cycle, while external ambiguities impede back-room stages. Through different paths, they contribute to tensions between government spheres, obstructing cooperation needed to address the ambiguities. Overall, the article contributes to a better understanding of the policy process in decentralized settings, unwraps the dynamic causal framework surrounding the ambiguities, and highlights the role of perceptions, not only by the electorate, but by public officials in particular.

  2. Geography and history education in Estonia: processes, policies and practices in an ethnically divided society from the late 1980s to the early 2000s

    Directory of Open Access Journals (Sweden)

    Jaanus Veemaa

    2016-09-01

    Full Text Available This article studies processes, policies and practices for geography and history education in Estonia. The analysis covers the societal transformation period in an ethnically divided society from the 1980s to the early 2000s characterized by Estonia’s disintegration from the Soviet Union towards the integration to the European Union and NATO. Geography and history education curricula, textbooks and related policies and practices promoted a particular national time-space by supporting the belongingness of Estonia into Europe, rejecting connections towards Russia and suggesting a division between ethnic Estonians and ethnically non-Estonian residents of Estonia. In geography and history textbooks, the Russian-speaking population, comprising then almost a third of the entire population of Estonia, was divided into non-loyal, semi-loyal and loyal groups of whom only the latter could be integrated in the Estonian time-space. The formal education policies for geography and history supported Estonia’s disintegration from the Soviet past and pawed way to integration to the western political and economic structures. However, challenging market and sensitive cultural contexts created peculiar, alternative and sometimes opposing local practices in geography and history education.

  3. Introductory physics of nuclear medicine. Third edition

    International Nuclear Information System (INIS)

    Chandra, R.

    1987-01-01

    The new third edition includes essential details and many examples and problems taken from the routine practice of nuclear medicine. Basic principles and underlying concepts are explained, although it is assumed that the reader has some current use as a bone densitometer. For resident physicians in nuclear medicine, residents in pathology, radiology, and internal medicine, and students of nuclear medicine technology, the third edition offers a simplified and reliable approach to the physics and basic sciences of nuclear medicine

  4. Nuclear electronics laboratory manual 1989 edition

    International Nuclear Information System (INIS)

    1989-10-01

    This manual is a joint product of several electronics experts who have been associated with IAEA activity in this field for many years. It is based on the experience of conducting twenty-three training courses on nuclear electronics. Compared with the first edition, published 1984, this edition contains many new experiments, mainly on the advanced technical level. The total number of experiments and special projects is 58. Tabs and figs

  5. Non-GMO genetically edited crop plants.

    Science.gov (United States)

    Kanchiswamy, Chidananda Nagamangala; Malnoy, Mickael; Velasco, Riccardo; Kim, Jin-Soo; Viola, Roberto

    2015-09-01

    Direct delivery of purified Cas9 protein with guide RNA into plant cells, as opposed to plasmid-mediated delivery, displays high efficiency and reduced off-target effects. Following regeneration from edited cells, the ensuing plant is also likely to bypass genetically modified organism (GMO) legislation as the genome editing complex is degraded in the recipient cells. Copyright © 2015 Elsevier Ltd. All rights reserved.

  6. The Ethics of Germline Gene Editing

    OpenAIRE

    Gyngell, Christopher; Douglas, Thomas; Savulescu, Julian

    2016-01-01

    Germline Gene Editing (GGE) has enormous potential both as a research tool and a therapeutic intervention. While other types of gene editing are relatively uncontroversial, GGE has been strongly resisted. In this paper, we analyze the ethical arguments for and against pursuing GGE, which we take to consist in allowing and funding its development. We argue there is a strong case for pursuing GGE for the prevention of disease. We then examine objections that have been raised against pursuing GG...

  7. Genome Editing in Sugarcane: Challenges Ahead

    OpenAIRE

    Mohan, Chakravarthi

    2016-01-01

    Genome editing opens new and unique opportunities for researchers to enhance crop production. Until 2013, the zinc finger nucleases (ZFNs) and transcription activator-like effector nucleases (TALENs) were the key tools used for genome editing applications. The advent of RNA-guided engineered nucleases - the type II clustered regularly interspaced short palindromic repeat (CRISPR)/Cas9 (CRISPR-associated) system from Streptococcus pyogenes holds great potential since it is simple, effective an...

  8. A genome editing primer for the hematologist

    OpenAIRE

    Hoban, Megan D.; Bauer, Daniel E.

    2016-01-01

    Gene editing enables the site-specific modification of the genome. These technologies have rapidly advanced such that they have entered common use in experimental hematology to investigate genetic function. In addition, genome editing is becoming increasingly plausible as a treatment modality to rectify genetic blood disorders and improve cellular therapies. Genome modification typically ensues from site-specific double-strand breaks and may result in a myriad of outcomes. Even single-strand ...

  9. Solar engineering of thermal processes

    CERN Document Server

    Duffie, John A

    2013-01-01

    The updated fourth edition of the ""bible"" of solar energy theory and applications Over several editions, Solar Engineering of Thermal Processes has become a classic solar engineering text and reference. This revised Fourth Edition offers current coverage of solar energy theory, systems design, and applications in different market sectors along with an emphasis on solar system design and analysis using simulations to help readers translate theory into practice. An important resource for students of solar engineering, solar energy, and alternative energy as well

  10. Computational Physics - 2nd Edition

    Science.gov (United States)

    Thijssen, J. M.

    1998-11-01

    This second edition describes the computational methods used in theoretical physics, and has been fully updated. New sections have been added to cover finite element methods and lattice Boltzmann simulation, density functional theory, quantum molecular dynamics, Monte Carlo simulation, and diagonalisation of one-dimensional quantum systems. It covers many different areas of physics research and different computational methodologies, including computational methods such as Monte Carlo and molecular dynamics, various electronic structure methodologies, methods for solving partial differential equations, and lattice gauge theory. Throughout the book the relations between the methods used in different fields of physics are emphasised. Several new programs are described and can be downloaded from www.cambridge.org/9780521833462. The book requires a background in elementary programming, numerical analysis, and field theory, as well as undergraduate knowledge on condensed matter theory and statistical physics. It will be of interest to graduate students and researchers in theoretical, computational and experimental physics. Completely revised with new chapters including finite element methods and lattice Boltzmann simulation Describes several new programs which can be downloaded from www.cambridge.org/9780521833462 Contains questions on theory and implementation at the end of each chapter

  11. Genome editing with engineered nucleases in plants.

    Science.gov (United States)

    Osakabe, Yuriko; Osakabe, Keishi

    2015-03-01

    Numerous examples of successful 'genome editing' now exist. Genome editing uses engineered nucleases as powerful tools to target specific DNA sequences to edit genes precisely in the genomes of both model and crop plants, as well as a variety of other organisms. The DNA-binding domains of zinc finger (ZF) proteins were the first to be used as genome editing tools, in the form of designed ZF nucleases (ZFNs). More recently, transcription activator-like effector nucleases (TALENs), as well as the clustered regularly interspaced short palindromic repeats/Cas9 (CRISPR/Cas9) system, which utilizes RNA-DNA interactions, have proved useful. A key step in genome editing is the generation of a double-stranded DNA break that is specific to the target gene. This is achieved by custom-designed endonucleases, which enable site-directed mutagenesis via a non-homologous end-joining (NHEJ) repair pathway and/or gene targeting via homologous recombination (HR) to occur efficiently at specific sites in the genome. This review provides an overview of recent advances in genome editing technologies in plants, and discusses how these can provide insights into current plant molecular biology research and molecular breeding technology. © The Author 2014. Published by Oxford University Press on behalf of Japanese Society of Plant Physiologists. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  12. The concern for nature, a natural process for public policy? How to promote sustainable development in urban environmental agendas

    Directory of Open Access Journals (Sweden)

    María de los Ángeles Barrionuevo Mora

    2016-11-01

    Full Text Available Ecuador is a leader worldwide for its recognition of the Rights of Nature and the Rights of the City in its Constitution. In so far as Quito, its capital, has positioned itself among the first municipalities that have demonstrated their compliance with the international commitments on climate change, it is a relevant case study. From the experience of this city, we aim to identify the main factors that contribute to local government taking on a sustainability agenda. Although the national and international context influence on the positioning of such topics, such factors as leadership, the influence of international networks, the level of specialization of the bureaucratic apparatus and local regulations have permitted to include issues related to sustainable development in the public policy agenda and thus have given visibility to cities as relevant actors in the pursuit of sustainable development.

  13. Repfinder: Finding approximately repeated scene elements for image editing

    KAUST Repository

    Cheng, Ming-Ming

    2010-07-26

    Repeated elements are ubiquitous and abundant in both manmade and natural scenes. Editing such images while preserving the repetitions and their relations is nontrivial due to overlap, missing parts, deformation across instances, illumination variation, etc. Manually enforcing such relations is laborious and error-prone. We propose a novel framework where user scribbles are used to guide detection and extraction of such repeated elements. Our detection process, which is based on a novel boundary band method, robustly extracts the repetitions along with their deformations. The algorithm only considers the shape of the elements, and ignores similarity based on color, texture, etc. We then use topological sorting to establish a partial depth ordering of overlapping repeated instances. Missing parts on occluded instances are completed using information from other instances. The extracted repeated instances can then be seamlessly edited and manipulated for a variety of high level tasks that are otherwise difficult to perform. We demonstrate the versatility of our framework on a large set of inputs of varying complexity, showing applications to image rearrangement, edit transfer, deformation propagation, and instance replacement. © 2010 ACM.

  14. Advancing Crop Transformation in the Era of Genome Editing.

    Science.gov (United States)

    Altpeter, Fredy; Springer, Nathan M; Bartley, Laura E; Blechl, Ann E; Brutnell, Thomas P; Citovsky, Vitaly; Conrad, Liza J; Gelvin, Stanton B; Jackson, David P; Kausch, Albert P; Lemaux, Peggy G; Medford, June I; Orozco-Cárdenas, Martha L; Tricoli, David M; Van Eck, Joyce; Voytas, Daniel F; Walbot, Virginia; Wang, Kan; Zhang, Zhanyuan J; Stewart, C Neal

    2016-07-01

    Plant transformation has enabled fundamental insights into plant biology and revolutionized commercial agriculture. Unfortunately, for most crops, transformation and regeneration remain arduous even after more than 30 years of technological advances. Genome editing provides novel opportunities to enhance crop productivity but relies on genetic transformation and plant regeneration, which are bottlenecks in the process. Here, we review the state of plant transformation and point to innovations needed to enable genome editing in crops. Plant tissue culture methods need optimization and simplification for efficiency and minimization of time in culture. Currently, specialized facilities exist for crop transformation. Single-cell and robotic techniques should be developed for high-throughput genomic screens. Plant genes involved in developmental reprogramming, wound response, and/or homologous recombination should be used to boost the recovery of transformed plants. Engineering universal Agrobacterium tumefaciens strains and recruiting other microbes, such as Ensifer or Rhizobium, could facilitate delivery of DNA and proteins into plant cells. Synthetic biology should be employed for de novo design of transformation systems. Genome editing is a potential game-changer in crop genetics when plant transformation systems are optimized. © 2016 American Society of Plant Biologists. All rights reserved.

  15. Science and Mathematics Faculty Responses to a Policy-Based Initiative: Change Processes, Self-Efficacy Beliefs, and Department Culture

    Science.gov (United States)

    Ellett, Chad D.; Demir, Kadir; Monsaas, Judith

    2015-01-01

    The purpose of this study was to examine change processes, self-efficacy beliefs, and department culture and the roles these elements play in faculty engagement in working in K-12 schools. The development of three new web-based measures of faculty perceptions of change processes, self-efficacy beliefs, and department culture are described. The…

  16. The sun and space weather Second Edition

    CERN Document Server

    Hanslmeier, Arnold

    2007-01-01

    This second edition is a great enhancement of literature which will help the reader get deeper into the specific topics. There are new sections included such as space weather data sources and examples, new satellite missions, and the latest results. At the end a comprehensive index is given which will allow the reader to quickly find his topics of interest. The Sun and Space weather are two rapidly evolving topics. The importance of the Sun for the Earth, life on Earth, climate and weather processes was recognized long ago by the ancients. Now, for the first time there is a continuous surveillance of solar activity at nearly all wavelengths. These data can be used to improve our understanding of the complex Sun-Earth interaction. The first chapters of the book deal with the Sun as a star and its activity phenomena as well as its activity cycle in order to understand the complex physics of the Sun-Earth system. The reader will see that there are many phenomena but still no definite explanations and models exis...

  17. A comprehensive overview of computational resources to aid in precision genome editing with engineered nucleases.

    Science.gov (United States)

    Periwal, Vinita

    2017-07-01

    Genome editing with engineered nucleases (zinc finger nucleases, TAL effector nucleases s and Clustered regularly inter-spaced short palindromic repeats/CRISPR-associated) has recently been shown to have great promise in a variety of therapeutic and biotechnological applications. However, their exploitation in genetic analysis and clinical settings largely depends on their specificity for the intended genomic target. Large and complex genomes often contain highly homologous/repetitive sequences, which limits the specificity of genome editing tools and could result in off-target activity. Over the past few years, various computational approaches have been developed to assist the design process and predict/reduce the off-target activity of these nucleases. These tools could be efficiently used to guide the design of constructs for engineered nucleases and evaluate results after genome editing. This review provides a comprehensive overview of various databases, tools, web servers and resources for genome editing and compares their features and functionalities. Additionally, it also describes tools that have been developed to analyse post-genome editing results. The article also discusses important design parameters that could be considered while designing these nucleases. This review is intended to be a quick reference guide for experimentalists as well as computational biologists working in the field of genome editing with engineered nucleases. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  18. Mitochondrial Genome Evolution and a Novel RNA Editing System in Deep-Branching Heteroloboseids.

    Science.gov (United States)

    Yang, Jiwon; Harding, Tommy; Kamikawa, Ryoma; Simpson, Alastair G B; Roger, Andrew J

    2017-05-01

    Discoba (Excavata) is an evolutionarily important group of eukaryotes that includes Jakobida, with the most bacterial-like mitochondrial genomes known, and Euglenozoa, many of which have extensively fragmented mitochondrial genomes. However, little is known about the mitochondrial genomes of Heterolobosea, the third main group of Discoba. Here, we studied two heteroloboseids-an undescribed amoeba "BB2" and Pharyngomonas kirbyi. Phylogenomic analysis revealed that they form a clade that is a sister group to all other Heterolobosea. We characterized the mitochondrial genomes of BB2 and P. kirbyi, which encoded 44 and 48 putative protein-coding genes respectively. Their gene contents were similar to that of Naegleria. In BB2, mitochondrially encoded RNAs were heavily edited, with ∼500 mononucleotide insertion events, mostly guanosines. These insertions always have the same identity as an adjacent nucleotide. Editing occurs in all ribosomal RNAs and protein-coding transcripts except one, and half of the transfer RNAs. Analysis of Illumina deep-sequencing data suggested that this RNA editing is very accurate and efficient, and most likely co-transcriptional. The dissimilarity of this editing process to other RNA editing phenomena in discobids, as well as its apparent absence in P. kirbyi, suggest that this remarkably extensive system of insertional editing evolved independently in the BB2 lineage, after its divergence from the P. kirbyi lineage. © The Author 2017. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

  19. Book Review: New Perspectives on Technical Editing

    Science.gov (United States)

    Murphy, A. J. (Ed.); Sterken, Christiaan

    2012-08-01

    New Perspectives on Technical Editing by Avon J. Murphy (ed.) ISBN : 978-0895033949 (2010) Baywood Publishing Company Inc, Hardcover, 210 pages, 35.5 GBP This book presents a collection of 10 chapters dealing with diverse aspects of technical editing (ie, editorial planning, and analysis and structural changes made to other people's technological documents): research in technical editing, trends and teaching of technical editing, copyediting, and technical journal editing. The role and function of the modern journal and book editor is also dealt with in detail. Each chapter is written by an expert in the field: senior editors, university professors in technical communication, technical writers and linguists. The ever-evolving role of the editor is clearly elucidated in several historical reviews, and in the descriptions of the expectations for the future. A very striking aspect of this book is its extensive collection of bibliographic resources: every chapter lists dozens of very useful references, and the closing chapter, and annotated bibliography, contain many not so well known references, and are most useful. All in all, the book is a treasure trove listing more than 400 references, in addition to numerous webpage URLs embedded in the texts. The book is designed to help the reader to understand current practices and norms in technical editing, and to help to take action in editing as well as in teaching and educating would-be editors. The audience for this book thus includes editors and teachers, but also writers, researchers and students. A deep reading of this book will result in a better understanding of the difference between full technical editing and its much narrower component so well known as copyediting, and will convince any prospective editor that editing should not be undertaken if the people involved do not master the art of precision and accuracy in technical (as well as in human) communication, do not possess the technical know how and computer

  20. Reshaping skills policy in South Africa: structures, policies and ...

    African Journals Online (AJOL)

    Reshaping skills policy in South Africa: structures, policies and processes. ... New Agenda: South African Journal of Social and Economic Policy ... South African skills development policy since the promulgation of the Skills Development Act of 1998 has undergone a number of different iterations or attempts at accelerating ...

  1. Introduction to stochastic processes

    CERN Document Server

    Cinlar, Erhan

    2013-01-01

    Clear presentation employs methods that recognize computer-related aspects of theory. Topics include expectations and independence, Bernoulli processes and sums of independent random variables, Markov chains, renewal theory, more. 1975 edition.

  2. Transition Toolkit 3.0: Meeting the Educational Needs of Youth Exposed to the Juvenile Justice System. Third Edition

    Science.gov (United States)

    Clark, Heather Griller; Mathur, Sarup; Brock, Leslie; O'Cummings, Mindee; Milligan, DeAngela

    2016-01-01

    The third edition of the National Technical Assistance Center for the Education of Neglected or Delinquent Children and Youth's (NDTAC's) "Transition Toolkit" provides updated information on existing policies, practices, strategies, and resources for transition that build on field experience and research. The "Toolkit" offers…

  3. 76 FR 74803 - Laboratory Animal Welfare: Adoption and Implementation of the Eighth Edition of the Guide for the...

    Science.gov (United States)

    2011-12-01

    ...: Adoption and Implementation of the Eighth Edition of the Guide for the Care and Use of Laboratory Animals... the Guide for the Care and Use of Laboratory Animals (Guide) and has determined to adopt the 8th... the PHS Policy on Humane Care and Use of Laboratory Animals, that they have met the required schedule...

  4. Solar Powering Your Community: A Guide for Local Governments; Second Edition

    Energy Technology Data Exchange (ETDEWEB)

    2011-01-01

    DOE designed this guide "Solar Powering Your Community: A Guide for Local Governments" to assist local government officials and stakeholders in designing and implementing strategic local solar plans. The 2011 edition contains the most recent lessons and successes from the 25 Solar America Cities and other communities promoting solar energy. Because DOE recognizes that there is no one path to solar market development, this guide introduces a range of policy and program options that can help a community build a local solar infrastructure.

  5. Communications Style Guide. Fourth Edition

    Science.gov (United States)

    2010-08-01

    such as EBSCO or STINET Bibliography: Kan, Shirley A. China and Proliferation of Weapons of Mass Destruction and Missiles: Policy Issues. CRS Report...17. Journal Articles from Electronic Databases such as ProQuest, JSTOR, and EBSCO Bibliography: Hammes, T. X. “The Emergence of 5th Generation...Time, June 11, 2007, 43. Magazine Articles from Electronic Databases such as ProQuest, EBSCO , and LexisNexis Bibliography: McGirk

  6. Residential Wiring. Fourth Edition. Teacher Edition [and] Student Guide [and] Student Workbook.

    Science.gov (United States)

    Taylor, Mark

    Residential Wiring, the second publication in a series of three wiring publications, prepares students for entry-level employment in the residential wiring trade. Instructional materials include a teacher edition, student guide, and student workbook. The teacher edition begins with introductory pages, including a training and competency profile,…

  7. English-to-Japanese Translation vs. Dictation vs. Post-editing

    DEFF Research Database (Denmark)

    Carl, Michael; Aizawa, Akiko; Yamada, Masaru

    2016-01-01

    post-editing. The transcription of the spoken data, keyboard logging and eye-tracking data were recorded with Translog-II, post-processed and integrated into the CRITT Translation Process Research-DB (TPR-DB), which is publicly available under a creative commons license. The paper presents the ENJA15...

  8. Standards of specialized diabetes care. Edited by Dedov II, Shestakova MV (6th edition

    Directory of Open Access Journals (Sweden)

    Ivan Ivanovich Dedov

    2013-06-01

    Full Text Available Dear Colleagues!We are glad to present the 6th Edition of Standards of Diabetes Care. These evidence-based guidelines were designed to standardize and facilitate diabetes care in all regions of the Russian Federation. The Standards are updated on the regular basis to incorporate new data and relevant recommendations from national and international clinical societies, including World Health Organization Guidelines (WHO, 2011, International Diabetes Federation (IDF, 2011, American Diabetes Association (ADA, 2013, American Association of Clinical Endocrinologists (AACE, 2009, International Society for Pediatric and Adolescent Diabetes (ISPAD, 2009 and Russian Association of Endocrinologists (RAE, 2011, 2012. Current edition of the “Standards” also integrates results of completed randomized clinical trials (ADVANCE, ACCORD, VADT, UKPDS, etc., as well as findings from the national studies of diabetes mellitus (DM, conducted in close partnership with a number of Russian hospitals.Latest data indicates that prevalence of DM increased during the last decade more than two-fold, reaching some 371 million patients by 2013. According to the current estimation by the International Diabetes Federation, every tenth inhabitant of the planet will be suffering from DM by 2030. These observations resulted in the UN Resolution 61/225 passed on 20.12.2006 that encouraged all Member States “to develop national policies for the prevention, treatment and care of diabetes”.Like many other countries, Russian Federation experiences a sharp rise in the prevalence of DM. According to Russian State Diabetes Register, there are at least 3.799 million patients with DM in this country. However, the epidemiological survey conducted by the Federal Endocrinology Research Centre during 2002-2010 suggests that actual prevalence is 3 to 4 times greater than the officially recognized and, by this estimate, amounts to 9-10 million persons, comprising 7% of the

  9. How much participation makes a participatory process legitimate? Observations from participants in forestry policy-making and nuclear weapons complex management

    International Nuclear Information System (INIS)

    Tuler, S.

    1997-01-01

    Public participation has received increasing attention as a means for improving research, policy-making, and decision-making in a variety of contexts. Regulators have experimented with a variety of participatory approaches to improve the legitimacy of outcomes in the eyes of diverse publics. In this paper the authors will explore how participants (as opposed to planners) perceived legitimacy of both processes and outcomes in planning processes. Data from two case studies will be presented: (1) a forestry planning process in the northeastern US and (2) environmental health, waste management, and clean-up activities in the US nuclear weapons complex. The data reveal that judgments about the appropriateness of particular forms of participation and about the quality of participation can be a critical factor in perceived legitimacy of processes and outcomes, and that judgments of appropriateness and quality are grounded in the experiences of individual participants. In addition, linkages between judgments about the adequacy of participation and legitimacy can be mediated by historical interactions and judgments of trust. Implications for the design of participatory processes will be discussed

  10. Smoke-free policy development in Italy through the legislative process of the ban 2000-2005, and press media review 1998-2008

    Directory of Open Access Journals (Sweden)

    Giuseppe Gorini

    2011-01-01

    Full Text Available The objective of this article is to describe the process of approval of the Italian smoking ban, enacted in 2005. The method is to conduct a review of proposed and approved legislation 20002005, and of articles published in Italian newspapers, 1998-2008. Enabling factors in the process were: the leadership of two consecutive Health Ministers, both physicians, who introduced the bill four times between 2000-2002; the repeated presentation and final approval of the bill as an amendment within a bill on public administration which enabled timely approval of the ban; and the stringent air quality standards in the 2003 regulation that made building smoking rooms impracticable and prohibitively expensive. Limiting factors in the process were: the 6-month delay in approving the regulation on smoking rooms; the 1.5-year delay in approving the regulation establishing owners' responsibility for enforcing the ban in hospitality premises and the legal action in August 2005, which shifted responsibility for enforcement to police. Eighty-three percent of the 808 articles published on smoking in 1998-2008 were released between 2000-2005, during the policy process. While the press devoted considerable attention to the issues raised by the hospitality sector, the long legislative process of the bill and its regulations also stimulated coverage on tobacco control issues.

  11. Smoke-free policy development in Italy through the legislative process of the ban 2000-2005, and press media review 1998-2008.

    Science.gov (United States)

    Gorini, Giuseppe; Currie, Laura; Spizzichino, Lorenzo; Galeone, Daniela; Lopez, Maria J

    2011-01-01

    The objective of this article is to describe the process of approval of the Italian smoking ban, enacted in 2005. The method is to conduct a review of proposed and approved legislation 2000- 2005, and of articles published in Italian newspapers, 1998-2008. Enabling factors in the process were: the leadership of two consecutive Health Ministers, both physicians, who introduced the bill four times between 2000-2002; the repeated presentation and final approval of the bill as an amendment within a bill on public administration which enabled timely approval of the ban; and the stringent air quality standards in the 2003 regulation that made building smoking rooms impracticable and prohibitively expensive. Limiting factors in the process were: the 6-month delay in approving the regulation on smoking rooms; the 1.5-year delay in approving the regulation establishing owners' responsibility for enforcing the ban in hospitality premises and the legal action in August 2005, which shifted responsibility for enforcement to police. Eighty-three percent of the 808 articles published on smoking in 1998-2008 were released between 2000-2005, during the policy process. While the press devoted considerable attention to the issues raised by the hospitality sector, the long legislative process of the bill and its regulations also stimulated coverage on tobacco control issues.

  12. BOOK REVIEW: Quantum Gravity: third edition Quantum Gravity: third edition

    Science.gov (United States)

    Rovelli, Carlo

    2012-09-01

    The request by Classical and Quantum Gravity to review the third edition of Claus Kiefer's 'Quantum Gravity' puts me in a slightly awkward position. This is a remarkably good book, which every person working in quantum gravity should have on the shelf. But in my opinion quantum gravity has undergone some dramatic advances in the last few years, of which the book makes no mention. Perhaps the omission only attests to the current vitality of the field, where progress is happening fast, but it is strange for me to review a thoughtful, knowledgeable and comprehensive book on my own field of research, which ignores what I myself consider the most interesting results to date. Kiefer's book is unique as a broad introduction and a reliable overview of quantum gravity. There are numerous books in the field which (often notwithstanding titles) focus on a single approach. There are also countless conference proceedings and article collections aiming to be encyclopaedic, but offering disorganized patchworks. Kiefer's book is a careful and thoughtful presentation of all aspects of the immense problem of quantum gravity. Kiefer is very learned, and brings together three rare qualities: he is pedagogical, he is capable of simplifying matter to the bones and capturing the essential, and he offers a serious and balanced evaluation of views and ideas. In a fractured field based on a major problem that does not yet have a solution, these qualities are precious. I recommend Kiefer's book to my students entering the field: to work in quantum gravity one needs a vast amount of technical knowledge as well as a grasp of different ideas, and Kiefer's book offers this with remarkable clarity. This novel third edition simplifies and improves the presentation of several topics, but also adds very valuable new material on quantum gravity phenomenology, loop quantum cosmology, asymptotic safety, Horava-Lifshitz gravity, analogue gravity, the holographic principle, and more. This is a testament

  13. Development of the regional policy process for air pollution in South Asia, southern Africa and Latin America

    CSIR Research Space (South Africa)

    Hicks, WK

    2001-08-01

    Full Text Available issues in three sub-regions of three continents. Experiences gained through activities within a programme on Regional Air Pollution in Developing Countries are used to illustrate progress. The sub-regional process in South Asia developed through a series...

  14. Genome Editing of Monogenic Neuromuscular Diseases

    Science.gov (United States)

    Long, Chengzu; Amoasii, Leonela; Bassel-Duby, Rhonda; Olson, Eric N.

    2017-01-01

    IMPORTANCE Muscle weakness, the most common symptom of neuromuscular disease, may result from muscle dysfunction or may be caused indirectly by neuronal and neuromuscular junction abnormalities. To date, more than 780 monogenic neuromuscular diseases, linked to 417 different genes, have been identified in humans. Genome-editing methods, especially the CRISPR (clustered regularly interspaced short palindromic repeats)–Cas9 (CRISPR-associated protein 9) system, hold clinical potential for curing many monogenic disorders, including neuromuscular diseases such as Duchenne muscular dystrophy, spinal muscular atrophy, amyotrophic lateral sclerosis, and myotonic dystrophy type 1. OBJECTIVES To provide an overview of genome-editing approaches; to summarize published reports on the feasibility, efficacy, and safety of current genome-editing methods as they relate to the potential correction of monogenic neuromuscular diseases; and to highlight scientific and clinical opportunities and obstacles toward permanent correction of disease-causing mutations responsible for monogenic neuromuscular diseases by genome editing. EVIDENCE REVIEW PubMed and Google Scholar were searched for articles published from June 30, 1989, through June 9, 2016, using the following keywords: genome editing, CRISPR-Cas9, neuromuscular disease, Duchenne muscular dystrophy, spinal muscular atrophy, amyotrophic lateral sclerosis, andmyotonic dystrophy type 1. The following sources were reviewed: 341 articles describing different approaches to edit mammalian genomes; 330 articles describing CRISPR-Cas9–mediated genome editing in cell culture lines (in vitro) and animal models (in vivo); 16 websites used to generate single-guide RNA; 4 websites for off-target effects; and 382 articles describing viral and nonviral delivery systems. Articles describing neuromuscular diseases, including Duchenne muscular dystrophy, spinal muscular atrophy, amyotrophic lateral sclerosis, and myotonic dystrophy type 1

  15. Problematizations in Health Policy

    Directory of Open Access Journals (Sweden)

    Carol Bacchi

    2016-06-01

    Full Text Available This article directs attention to the significance, for health promotion advocates, of reflecting on how “problems” are constituted, or brought into existence, as particular sorts of problems, within policies and policy proposals. To this end, it introduces a poststructural analytic strategy called “What’s the Problem Represented to be?” (WPR approach, and contrasts this perspective to the ways in which “problems” are commonly conceptualized in health policy analyses (e.g., “a problem stream,” “wicked problems”. Such a perspective offers a significant rethinking of the conventional emphasis on agenda setting and policy-making processes in considering the meaning of success or failure in health policy initiatives. The starting point is a close analysis of items that are “successful,” in the sense that they make the political agenda, to see how representations of “problems” within selected policies limit what is talked about as possible or desirable, or as impossible and undesirable. This form of analysis thus enables critical reflections on the substantive content of policy initiatives in health policy. The article takes a step back from policy process theories, frameworks, and models to offer reflections at the level of paradigms. Highlighting potential dangers and limitations in positivism, interpretivism, and critical realism, it uses international, Australian, and South Australian examples in health policy to explore what poststructural policy analysis contributes to understanding the broad political influences shaping contemporary modes of rule.

  16. Energy Technology Roadmaps: A Guide to Development and Implementation. 2014 edition

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2014-03-01

    New low-carbon technologies show clear potential for transforming the global energy system, but a key challenge remains: what steps do governments and industry need to take to ensure their development and deployment? Roadmapping, used for decades in technology-intensive industries, is a useful tool to help address complicated issues strategically at the national, regional and global levels. To help turn political statements and analytical work into concrete action, the International Energy Agency (IEA) is developing a series of global roadmaps devoted to low-carbon energy technologies. Drawing upon the extensive IEA experience, this guide is aimed at providing countries and companies with the context, information and tools needed to design, manage and implement an effective energy technology roadmap process relevant to their own local circumstances and objectives. This edition of the Energy Technology Roadmaps: a guide to development and implementation includes more detailed guidance on how to identify key stakeholders, develop a technology baseline and development of indicators to help track progress against roadmap milestones. The IEA hopes that this guide and the examples and references it offers, together with the new IEA How2Guides, which provide technology-specific guidance, will help national and local policy makers and industry to develop strategies that accelerate the deployment of low-carbon energy technologies worldwide.

  17. Designed nucleases for targeted genome editing.

    Science.gov (United States)

    Lee, Junwon; Chung, Jae-Hee; Kim, Ho Min; Kim, Dong-Wook; Kim, Hyongbum

    2016-02-01

    Targeted genome-editing technology using designed nucleases has been evolving rapidly, and its applications are widely expanding in research, medicine and biotechnology. Using this genome-modifying technology, researchers can precisely and efficiently insert, remove or change specific sequences in various cultured cells, micro-organisms, animals and plants. This genome editing is based on the generation of double-strand breaks (DSBs), repair of which modifies the genome through nonhomologous end-joining (NHEJ) or homology-directed repair (HDR). In addition, designed nickase-induced generation of single-strand breaks can also lead to precise genome editing through HDR, albeit at relatively lower efficiencies than that induced by nucleases. Three kinds of designed nucleases have been used for targeted DSB formation: zinc-finger nucleases, transcription activator-like effector nucleases, and RNA-guided engineered nucleases derived from the bacterial clustered regularly interspaced short palindromic repeat (CRISPR)-Cas (CRISPR-associated) system. A growing number of researchers are using genome-editing technologies, which have become more accessible and affordable since the discovery and adaptation of CRISPR-Cas9. Here, the repair mechanism and outcomes of DSBs are reviewed and the three types of designed nucleases are discussed with the hope that such understanding will facilitate applications to genome editing. © 2015 Society for Experimental Biology, Association of Applied Biologists and John Wiley & Sons Ltd.

  18. Simulation-based algorithms for Markov decision processes

    CERN Document Server

    Chang, Hyeong Soo; Fu, Michael C; Marcus, Steven I

    2013-01-01

    Markov decision process (MDP) models are widely used for modeling sequential decision-making problems that arise in engineering, economics, computer science, and the social sciences.  Many real-world problems modeled by MDPs have huge state and/or action spaces, giving an opening to the curse of dimensionality and so making practical solution of the resulting models intractable.  In other cases, the system of interest is too complex to allow explicit specification of some of the MDP model parameters, but simulation samples are readily available (e.g., for random transitions and costs). For these settings, various sampling and population-based algorithms have been developed to overcome the difficulties of computing an optimal solution in terms of a policy and/or value function.  Specific approaches include adaptive sampling, evolutionary policy iteration, evolutionary random policy search, and model reference adaptive search. This substantially enlarged new edition reflects the latest developments in novel ...

  19. Safe meat-handling knowledge, attitudes and practices of private and government meat processing plants' workers: implications for future policy

    OpenAIRE

    ADESOKAN, H.K.; RAJI, A.O.Q.

    2014-01-01

    Summary Introduction. Food-borne disease outbreaks remain a major global health challenge and cross-contamination from raw meat due to poor handling is a major cause in developing countries. Adequate knowledge of meat handlers is important in limiting these outbreaks. This study evaluated and compared the safe meat-handling knowledge, attitudes and practices (KAP) of private (PMPP) and government meat processing plants' (GMPP) workers in south-western Nigeria. Methods. This cross sectional st...

  20. Further Evidence on the Effect of Acquisition Policy and Process on Cost Growth of Major Defense Acquisition Programs (Revised)

    Science.gov (United States)

    2016-08-01

    two significant findings. First, Major Defense Acquisition Programs (MDAPs) that entered Engineering and Manufacturing Development (EMD) during...First, Major Defense Acquisition Programs (MDAPs) that entered Engineering and Manufacturing Development (EMD) during “bust” funding climates on...Additionally, a major building block of McNamara’s process began operating in 1959. See William D. O’Neil and Gene H. Porter, “What to Buy ? The Role of