WorldWideScience

Sample records for policy osp update

  1. Update of Energy policy of Uruguay

    International Nuclear Information System (INIS)

    2004-08-01

    The National Energy Directorate from Uruguay called a contest for Update Policy L Energy of Uruguay so as to ensure energy supply at the lowest possible cost, with greater safety and lower environmental impact and taking account efficient use of the Energy. FIEL was selected to carry out the work planned within three months and responding to a broad agenda that included the following points in the order of the Terms of Reference of the contest (TORs): 3.1. Evaluation of the existing energy policy 3.2. relative price optimization fuel 3.3. Optimization of tax policy in fuel 3.4. assessment of cost and benefits of alternative import 3.5. strategic reserve 3.6. Ambiental impacts Identification 3.7. Recommendations to improve the framework regulatory 3.8. Institutional framework for the energy sector in Uruguay 3.9. Evaluation of potential of renewable national energy resources 3.10. Energy efficiency 3.11. Action Plan for the National Energy The report presents and order of the TORs. In the first chapter updates assessment of energy policy presented in the progress report. In point 3.2 approaching the economic costs of the various energy alternatives from the parities import and cost efficient products in non tradable. Along with the environmental costs estimated in Section 3.6 is evaluated in the 3.3 How should the taxes structure to take into account externalities generating energy. In Section 3.4 discusses different options imported and in 3.5 energy supply costs are assessed count a strategic reserve, which Uruguay has decided that it is in the form of capacity thermal generation. In paragraphs 3.7 and 3.8 governing institutions is analyzed and they plan the sector, not only from a regulatory point of view but also the organization Internal DNE. In 3.9 alternatives are discussed renewable resources from national and international studies existentes, and in 3.1 updating the results of a recent study on energy efficiency by the World Bank and the case of an eventual

  2. Update LADOTD policy on pile driving vibration management.

    Science.gov (United States)

    2012-02-01

    The main objective of this project was to update the current Louisiana Department of Transportation and Development (LADOTD) policy on pile driving vibration risk management with a focus on how to determine an appropriate vibration monitoring area. T...

  3. AGU's Updated Scientific Integrity and Professional Ethics Policy

    Science.gov (United States)

    McPhaden, M. J.

    2017-12-01

    AGU'S mission is to promote discovery in Earth and space science for the benefit of humanity. This mission can only be accomplished if all those engaged in the scientific enterprise uphold the highest standards of scientific integrity and professional ethics. AGU's Scientific Integrity and Professional Ethics Policy provides a set of principles and guidelines for AGU members, staff, volunteers, contractors, and non-members participating in AGU sponsored programs and activities. The policy has recently been updated to include a new code of conduct that broadens the definition of scientific misconduct to include discrimination, harassment, and bullying. This presentation provides the context for what motivated the updated policy, an outline of the policy itself, and a discussion of how it is being communicated and applied.

  4. Policy and practice in South African prisons: An update | Sloth ...

    African Journals Online (AJOL)

    Policy and practice in South African prisons: An update. Julia Sloth-Nielsen. Abstract. No Abstract. Full Text: EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT · AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's ...

  5. Thailand's role in updating ASEAN immigration policy

    Directory of Open Access Journals (Sweden)

    Palapan Kampan

    2017-09-01

    Full Text Available This research examined how the Association of Southeast Asian Nations (ASEAN can improve upon the common economic community through the revision of policies related to labor and migration. The literature review suggested that economic prosperity and growth are significantly related to national openness to naturalization and foreign investment. Citizenship laws from all 10 ASEAN states and several other nations were analyzed alongside economic indicators. Within ASEAN, Thailand is considered central to widespread immigration law changes due to its leadership role in the region. Human rights aspects of citizenship and migration were assessed and potential solutions posed for the high incidence of statelessness in Myanmar and Thailand. In order to support consistent, long-term economic growth and protection of human rights, the research recommends various statutory revisions and the implementation of an executive strategic plan to protect alien laborers. For the purposes of developing globally-competitive economies in ASEAN, the research supports expansive access to citizenship by descent, birthright, and by naturalization, with full recognition of multiple citizenship.

  6. The Policy on Gender Equality in Denmark - Update

    DEFF Research Database (Denmark)

    Agustin, Lise Rolandsen

    Upon request of the FEMM committee, this in-depth analysis updates a previous note published in October 2011 and describes Danish policies, practices and legislation within the area of women's rights and gender equality, covering the period from October 2011, when the Social Democrat-led government...... took office, to April 2015. During this period, the focus has been put on gender-based violence, leave policies, pay statistics, gender segregation in the labour market and in education, as well as sexual and reproductive health and rights. Earmarked leave for fathers and gender quota on company boards...

  7. On osp(2|2) conformal field theories

    International Nuclear Information System (INIS)

    Ding Xiangmao; Gould, Mark D; Mewton, Courtney J; Zhang Yaozhong

    2003-01-01

    We study the conformal field theories corresponding to current superalgebras osp(2|2) (1) k and osp(2|2) (2) k . We construct the free field realizations, screen currents and primary fields of these current superalgebras at general level k. All the results for osp(2|2) (2) k are new, and the results for the primary fields of osp(2|2) (1) k also seem to be new. Our results are expected to be useful in the supersymmetric approach to Gaussian disordered systems such as the random bond Ising model and the Dirac model

  8. Regulatory, legislative, and policy updates with anticoagulant use.

    Science.gov (United States)

    Fanikos, John; Buckley, Leo F; Aldemerdash, Ahmed; Terry, Kimberly J; Piazza, Gregory; Connors, Jean M; Goldhaber, Samuel Z

    2015-04-01

    Thromboembolism afflicts millions of patients annually in the United States and is associated with a significant cost burden. Recent advances in oral anticoagulation have provided clinicians with more options for management of these diseases. Accordingly, regulatory, legislative, and policy-making organizations have intervened with the aim of improving patient outcomes, ensuring patient safety, and reducing costs. There have been a number of recent developments in surveillance, litigation, and regulatory oversight that clinicians should recognize. In this review article we summarize key updates related to the management of anticoagulant therapy as it relates to thrombosis prevention and treatment.

  9. From osp(1|32)⊕osp(1|32) to the M-theory superalgebra: a contraction procedure

    Energy Technology Data Exchange (ETDEWEB)

    Fernández, J. J., E-mail: julio.j.fernandez@hotmail.es; Izquierdo, J. M., E-mail: izquierd@fta.uva.es; Olmo, M. A. del, E-mail: olmo@fta.uva.es [Universidad de Valladolid, Departamento de Física Teórica and IMUVA (Spain)

    2017-03-15

    We show the impossibility to obtain the D’auria–Fré-type superalgebras that allow for an underlying gauge theoretical structure of D = 11 supergravity from the superalgebra osp(1|32)⊕osp(1|32)−, by means of aWeimar-Woods contraction.

  10. The Shigella flexneri OspB effector: an early immunomodulator.

    Science.gov (United States)

    Ambrosi, Cecilia; Pompili, Monica; Scribano, Daniela; Limongi, Dolores; Petrucca, Andrea; Cannavacciuolo, Sonia; Schippa, Serena; Zagaglia, Carlo; Grossi, Milena; Nicoletti, Mauro

    2015-01-01

    Through the action of the type three secretion system (T3SS) Shigella flexneri delivers several effectors into host cells to promote cellular invasion, multiplication and to exploit host-cell signaling pathways to modulate the host innate immune response. Although much progress has been made in the understanding of many type III effectors, the molecular and cellular mechanism of the OspB effector is still poorly characterized. In this study we present new evidence that better elucidates the role of OspB as pro-inflammatory factor at very early stages of infection. Indeed, we demonstrate that, during the first hour of infection, OspB is required for full activation of ERK1/2 and p38 MAPKs and the cytosolic phospholipase A(2) (cPLA(2)). Activation of cPLA(2) ultimately leads to the production and secretion of PMN chemoattractant metabolite(s) uncoupled with release of IL-8. Moreover, we also present evidence that OspB is required for the development of the full and promptly inflammatory reaction characteristic of S. flexneri wild-type infection in vivo. Based on OspB and OspF similarity (both effectors share similar transcription regulation, temporal secretion into host cells and nuclear localization) we hypothesized that OspB and OspF effectors may form a pair aimed at modulating the host cell response throughout the infection process, with opposite effects. A model is presented to illustrate how OspB activity would promote S. flexneri invasion and bacterial dissemination at early critical phases of infection. Copyright © 2014 Elsevier GmbH. All rights reserved.

  11. Oil and Gas Emergency Policy: Slovak Republic 2011 update

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    In 2007, the IEA published ''Oil Supply Security: Emergency Response of IEA Countries''. This publication provides an overview of the IEA oil emergency response system and a detailed look at the specific systems in each IEA country for responding to an oil supply crisis. This publication represented the findings of a five year review cycle of the emergency response mechanisms in IEA member countries. Since the 2007 publication, the IEA has started a new cycle of reviews which now includes reviewing gas emergency policies. Rather than waiting for the completion of the current review cycle to renew this publication, the IEA will make available updates to the country chapters as these become available following the country's review.

  12. Oil and Gas Emergency Policy: Czech Republic 2010 update

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    This publication provides a detailed look at the specific systems in the Czech Republic for responding to an oil supply crisis. In 2007, the IEA published ''Oil Supply Security: Emergency Response of IEA Countries''. Rather than waiting for the completion of the current review cycle to renew this full publication, the IEA will provide updates to the country chapters as these become available following the specific country's review. The aim of series of publications is to provide an overview of the IEA oil emergency response system and a detailed look at the specific systems in each IEA country for responding to an oil supply crisis. The 2007 publication represented the findings of a five year review cycle of the emergency response mechanisms in IEA member countries. Since the 2007 publication, the IEA has started a new cycle of reviews which now includes reviewing gas emergency policies.

  13. Oil and Gas Emergency Policy: Spain 2011 update

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    In 2007, the IEA published ''Oil Supply Security: Emergency Response of IEA Countries''. This publication provides an overview of the IEA oil emergency response system and a detailed look at the specific systems in each IEA country for responding to an oil supply crisis. This publication represented the findings of a five year review cycle of the emergency response mechanisms in IEA member countries. Since the 2007 publication, the IEA has started a new cycle of reviews which now includes reviewing gas emergency policies. Rather than waiting for the completion of the current review cycle to renew this publication, the IEA will make available updates to the country chapters as these become available following the country's review.

  14. Oil and Gas Emergency Policy: Greece 2010 update

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    This publication provides a detailed look at the specific systems in Greece for responding to an oil supply crisis. In 2007, the IEA published ''Oil Supply Security: Emergency Response of IEA Countries''. Rather than waiting for the completion of the current review cycle to renew this full publication, the IEA will provide updates to the country chapters as these become available following the specific country's review. The aim of series of publications is to provide an overview of the IEA oil emergency response system and a detailed look at the specific systems in each IEA country for responding to an oil supply crisis. The 2007 publication represented the findings of a five year review cycle of the emergency response mechanisms in IEA member countries. Since the 2007 publication, the IEA has started a new cycle of reviews which now includes reviewing gas emergency policies.

  15. Oil and Gas Emergency Policy: Finland 2012 update

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-07-01

    In 2007, the IEA published ''Oil Supply Security: Emergency Response of IEA Countries''. This publication provides an overview of the IEA oil emergency response system and a detailed look at the specific systems in each IEA country for responding to an oil supply crisis. This publication represented the findings of a five year review cycle of the emergency response mechanisms in IEA member countries. Since the 2007 publication, the IEA has started a new cycle of reviews which now includes reviewing gas emergency policies. Rather than waiting for the completion of the current review cycle to renew this publication, the IEA will make available updates to the country chapters as these become available following the country's review.

  16. Oil and Gas Emergency Policy: Luxembourg 2010 update

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    This publication provides a detailed look at the specific systems in Luxembourg for responding to an oil supply crisis. In 2007, the IEA published ''Oil Supply Security: Emergency Response of IEA Countries''. Rather than waiting for the completion of the current review cycle to renew this full publication, the IEA will provide updates to the country chapters as these become available following the specific country's review. The aim of series of publications is to provide an overview of the IEA oil emergency response system and a detailed look at the specific systems in each IEA country for responding to an oil supply crisis. The 2007 publication represented the findings of a five year review cycle of the emergency response mechanisms in IEA member countries. Since the 2007 publication, the IEA has started a new cycle of reviews which now includes reviewing gas emergency policies.

  17. Oil and Gas Emergency Policy: Poland 2011 update

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    In 2007, the IEA published ''Oil Supply Security: Emergency Response of IEA Countries''. This publication provides an overview of the IEA oil emergency response system and a detailed look at the specific systems in each IEA country for responding to an oil supply crisis. This publication represented the findings of a five year review cycle of the emergency response mechanisms in IEA member countries. Since the 2007 publication, the IEA has started a new cycle of reviews which now includes reviewing gas emergency policies. Rather than waiting for the completion of the current review cycle to renew this publication, the IEA will make available updates to the country chapters as these become available following the country's review.

  18. Oil and Gas Emergency Policy: Italy 2010 update

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    This publication provides a detailed look at the specific systems in Italy for responding to an oil supply crisis. In 2007, the IEA published ''Oil Supply Security: Emergency Response of IEA Countries''. Rather than waiting for the completion of the current review cycle to renew this full publication, the IEA will provide updates to the country chapters as these become available following the specific country's review. The aim of series of publications is to provide an overview of the IEA oil emergency response system and a detailed look at the specific systems in each IEA country for responding to an oil supply crisis. The 2007 publication represented the findings of a five year review cycle of the emergency response mechanisms in IEA member countries. Since the 2007 publication, the IEA has started a new cycle of reviews which now includes reviewing gas emergency policies.

  19. Oil and Gas Emergency Policy: Australia 2011 update

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    In 2007, the IEA published ''Oil Supply Security: Emergency Response of IEA Countries''. This publication provides an overview of the IEA oil emergency response system and a detailed look at the specific systems in each IEA country for responding to an oil supply crisis. This publication represented the findings of a five year review cycle of the emergency response mechanisms in IEA member countries. Since the 2007 publication, the IEA has started a new cycle of reviews which now includes reviewing gas emergency policies. Rather than waiting for the completion of the current review cycle to renew this publication, the IEA will make available updates to the country chapters as these become available following the country's review.

  20. Oil and Gas Emergency Policy: Denmark 2011 update

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    In 2007, the IEA published ''Oil Supply Security: Emergency Response of IEA Countries''. This publication provides an overview of the IEA oil emergency response system and a detailed look at the specific systems in each IEA country for responding to an oil supply crisis. This publication represented the findings of a five year review cycle of the emergency response mechanisms in IEA member countries. Since the 2007 publication, the IEA has started a new cycle of reviews which now includes reviewing gas emergency policies. Rather than waiting for the completion of the current review cycle to renew this publication, the IEA will make available updates to the country chapters as these become available following the country's review.

  1. Oil and Gas Emergency Policy: Canada 2010 update

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    This publication provides a detailed look at the specific systems in Canada for responding to an oil supply crisis. In 2007, the IEA published ''Oil Supply Security: Emergency Response of IEA Countries''. Rather than waiting for the completion of the current review cycle to renew this full publication, the IEA will provide updates to the country chapters as these become available following the specific country's review. The aim of series of publications is to provide an overview of the IEA oil emergency response system and a detailed look at the specific systems in each IEA country for responding to an oil supply crisis. The 2007 publication represented the findings of a five year review cycle of the emergency response mechanisms in IEA member countries. Since the 2007 publication, the IEA has started a new cycle of reviews which now includes reviewing gas emergency policies.

  2. Oil and Gas Emergency Policy: Norway 2011 update

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    In 2007, the IEA published ''Oil Supply Security: Emergency Response of IEA Countries''. This publication provides an overview of the IEA oil emergency response system and a detailed look at the specific systems in each IEA country for responding to an oil supply crisis. This publication represented the findings of a five year review cycle of the emergency response mechanisms in IEA member countries. Since the 2007 publication, the IEA has started a new cycle of reviews which now includes reviewing gas emergency policies. Rather than waiting for the completion of the current review cycle to renew this publication, the IEA will make available updates to the country chapters as these become available following the country's review.

  3. Oil and Gas Emergency Policy: Ireland 2011 update

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    In 2007, the IEA published ''Oil Supply Security: Emergency Response of IEA Countries''. This publication provides an overview of the IEA oil emergency response system and a detailed look at the specific systems in each IEA country for responding to an oil supply crisis. This publication represented the findings of a five year review cycle of the emergency response mechanisms in IEA member countries. Since the 2007 publication, the IEA has started a new cycle of reviews which now includes reviewing gas emergency policies. Rather than waiting for the completion of the current review cycle to renew this publication, the IEA will make available updates to the country chapters as these become available following the country's review.

  4. Oil and Gas Emergency Policy: New Zealand 2010 update

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    This publication provides a detailed look at the specific systems in New Zealand for responding to an oil supply crisis. In 2007, the IEA published ''Oil Supply Security: Emergency Response of IEA Countries''. Rather than waiting for the completion of the current review cycle to renew this full publication, the IEA will provide updates to the country chapters as these become available following the specific country's review. The aim of series of publications is to provide an overview of the IEA oil emergency response system and a detailed look at the specific systems in each IEA country for responding to an oil supply crisis. The 2007 publication represented the findings of a five year review cycle of the emergency response mechanisms in IEA member countries. Since the 2007 publication, the IEA has started a new cycle of reviews which now includes reviewing gas emergency policies.

  5. Oil and Gas Emergency Policy: Hungary 2012 update

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-09-06

    This publication provides a detailed look at the specific systems in Hungary for responding to an oil supply crisis. In 2007, the IEA published ''Oil Supply Security: Emergency Response of IEA Countries''. Rather than waiting for the completion of the current review cycle to renew this full publication, the IEA will provide updates to the country chapters as these become available following the specific country's review. The aim of series of publications is to provide an overview of the IEA oil emergency response system and a detailed look at the specific systems in each IEA country for responding to an oil supply crisis. The 2007 publication represented the findings of a five year review cycle of the emergency response mechanisms in IEA member countries. Since the 2007 publication, the IEA has started a new cycle of reviews which now includes reviewing gas emergency policies.

  6. Oil and Gas Emergency Policy: Belgium 2010 update

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    In 2007, the IEA published ''Oil Supply Security: Emergency Response of IEA Countries''. This publication provides an overview of the IEA oil emergency response system and a detailed look at the specific systems in each IEA country for responding to an oil supply crisis. This publication represented the findings of a five year review cycle of the emergency response mechanisms in IEA member countries. Since the 2007 publication, the IEA has started a new cycle of reviews which now includes reviewing gas emergency policies. Rather than waiting for the completion of the current review cycle to renew this publication, the IEA will make available updates to the country chapters as these become available following the country's review.

  7. Oil and Gas Emergency Policy: France 2012 update

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-07-01

    In 2007, the IEA published ''Oil Supply Security: Emergency Response of IEA Countries''. This publication provides an overview of the IEA oil emergency response system and a detailed look at the specific systems in each IEA country for responding to an oil supply crisis. This publication represented the findings of a five year review cycle of the emergency response mechanisms in IEA member countries. Since the 2007 publication, the IEA has started a new cycle of reviews which now includes reviewing gas emergency policies. Rather than waiting for the completion of the current review cycle to renew this publication, the IEA will make available updates to the country chapters as these become available following the country's review.

  8. Oil and Gas Emergency Policy: Portugal 2011 update

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    In 2007, the IEA published ''Oil Supply Security: Emergency Response of IEA Countries''. This publication provides an overview of the IEA oil emergency response system and a detailed look at the specific systems in each IEA country for responding to an oil supply crisis. This publication represented the findings of a five year review cycle of the emergency response mechanisms in IEA member countries. Since the 2007 publication, the IEA has started a new cycle of reviews which now includes reviewing gas emergency policies. Rather than waiting for the completion of the current review cycle to renew this publication, the IEA will make available updates to the country chapters as these become available following the country's review.

  9. Oil and Gas Emergency Policy: Korea 2011 update

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    This publication provides a detailed look at the specific systems in the Republic of Korea for responding to an oil supply crisis. In 2007, the IEA published ''Oil Supply Security: Emergency Response of IEA Countries''. Rather than waiting for the completion of the current review cycle to renew this full publication, the IEA will provide updates to the country chapters as these become available following the specific country's review. The aim of series of publications is to provide an overview of the IEA oil emergency response system and a detailed look at the specific systems in each IEA country for responding to an oil supply crisis. The 2007 publication represented the findings of a five year review cycle of the emergency response mechanisms in IEA member countries. Since the 2007 publication, the IEA has started a new cycle of reviews which now includes reviewing gas emergency policies.

  10. Cloning and expression of soluble truncated variants of Borrelia OspA, OspB and Vmp7

    Energy Technology Data Exchange (ETDEWEB)

    Dunn, J.J.; Barbour, A.G.

    1996-11-05

    A method is provided for preparing soluble recombinant variations of Borrelia lipoproteins such as Borrelia burgdorferi outer surface protein A (OspA) and outer surface protein B (OspB), and B. hermsii variable major protein 7 (Vmp7). The method includes synthesizing a set of oligonucleotide primers, amplifying the template DNA utilizing the PCR, purifying the amplification products, cloning the amplification products into a suitable expression vector, transforming a suitable host utilizing the cloned expression vector, cultivating the transformed host for protein production and subsequently isolating and purifying the resulting protein. Also provided are soluble, recombinant variations of Borrelia burgdorferi outer surface protein A (OspA), outer surface protein B (OspB), and B. hermsii variable major protein 7 (Vmp7). The expression vectors harboring DNA encoding the recombinant variations, pET9-OspA, pET9-OspB and pET9-Vmp7, as well as the E. coli host BL21(DE3)/pLysS transformed with each of these vectors, are also disclosed. 38 figs.

  11. Cloning and expression of soluble truncated variants of Borrelia OspA, OspB and Vmp7

    Science.gov (United States)

    Dunn, John J.; Barbour, Alan G.

    1996-11-05

    A method is provided herein for preparing soluble recombinant variations of Borrelia lipoproteins such as Borrelia burgdorferi outer surface protein A (OspA) and outer surface protein B (OspB), and B. hermsii variable major protein 7 (Vmp7). The method includes synthesizing a set of oligonucleotide primers, amplifying the template DNA utilizing the PCR, purifying the amplification products, cloning the amplification products into a suitable expression vector, transforming a suitable host utilizing the cloned expression vector, cultivating the transformed host for protein production and subsequently isolating and purifying the resulting protein. Also provided are soluble, recombinant variations of Borrelia burgdorferi outer surface protein A (OspA), outer surface protein B (OspB), and B. hermsii variable major protein 7 (Vmp7). The expression vectors harboring DNA encoding the recombinant variations, pET9-OspA, pET9-OspB and pET9-Vmp7, as well as the E. coli host BL21(DE3)/pLysS transformed with each of these vectors, are also disclosed.

  12. Chimeric OspA genes, proteins and methods of use thereof

    Energy Technology Data Exchange (ETDEWEB)

    Crowe, Brian A.; Livey, Ian; O' Rourke, Maria; Schwendinger, Michael; Dunn, John J.; Luft, Benjamin J.

    2018-02-20

    The invention relates to the development of chimeric OspA molecules for use in a new Lyme vaccine. More specifically, the chimeric OspA molecules comprise the proximal portion from one OspA serotype, together with the distal portion from another OspA serotype, while retaining antigenic properties of both of the parent polypeptides. The chimeric OspA molecules are delivered alone or in combination to provide protection against a variety of Borrelia genospecies. The invention also provides methods for administering the chimeric OspA molecules to a subject in the prevention and treatment of Lyme disease or borreliosis.

  13. Assessment of medical students by OSPE method in pathology

    Directory of Open Access Journals (Sweden)

    Prasana K Bandi

    2012-01-01

    Full Text Available Objective structured practical examination (OSPE is a practical exam system wherein there is a series of stations at which students work through tasks designed to test various skills and are tested using agreed check lists with observers sitting at some of the stations. It has been found to be objective, valid and reliable. It also eliminates examiner bias. The purpose of this study is to introduce OSPE both as an evaluation and a teaching tool and to draw attention to its advantages and disadvantages. We designed an OSPE that tested all the above objectives satisfactorily. The OSPE exam was conducted in the department of pathology during the second internal assessment of the students. This method was the compared with the conventional method of practical exam conducted during the first internal assessment of the same batch of students. The results showed that OSPE tests different desired components of competence better. It is an objective, valid and reliable method and gets rid of variation due to examiner bias. It has a better discrimination index on merit. Interpretative exercises are the most relevant part and deserve the lion’s share of total marks. Students feel more comfortable and less stressed to perform the exam.

  14. Innovation Policy of the European Union: Concept Strategic Update and Instruments Improvement

    Directory of Open Access Journals (Sweden)

    Belal Hassouna

    2013-01-01

    Full Text Available The article characterizes formation of EU innovation policy and its conceptual update, which has strategic character and is concerned with the social and economic model change, determines differences between EU innovation policy and national politics and the forms of its implementation, detects major changes of EU innovation policy instruments, which were the result of support concept and innovation regulations change.

  15. Assessment of medical students by OSPE method in pathology ...

    African Journals Online (AJOL)

    ABSTRACT: Objective structured practical examination (OSPE) is a practical exam system wherein there is a series of stations at which students work through tasks designed to test various skills and are tested using agreed check lists with observers sitting at some of the stations. It has been found to be objective, valid and ...

  16. Economic Motives for Adopting LGBT-Related Workplace Policies (Updated)

    OpenAIRE

    Mallory, Christy; Sears, Brad

    2011-01-01

    Over ninety percent of the 100 top companies in the U.S.—the top 50 federal contractors and the top 50 Fortune 500 companies—have policies prohibiting discrimination based on sexual orientation, and 78% of the companies have policies prohibiting discrimination based on gender identity. In comparison to a 2011 study, based on 2010 data, there has been a 50% increase in the number of top federal contractors with gender identity non-discrimination policies and a 26% increase in the number of top...

  17. Teledermatology: An updated overview of clinical applications and reimbursement policies

    Directory of Open Access Journals (Sweden)

    M. Campagna

    2017-09-01

    Full Text Available Telemedicine is an emerging field in healthcare that provides services from different medical specialties to patients all around the world. One of the specialties in telemedicine, teledermatology, has grown exponentially as a cost-effective way to implement dermatological healthcare to underserved areas and populations. This article reviews the literature that pertains to the cost-effectiveness, reliability, public access, patient satisfaction, and reimbursement policies of teledermatology. Teledermatology was found to be cost-effective and reliable in reducing in-person visits and time away from work, and allows for the faster delivery of care. However, reimbursement policies for teledermatology services are rather new and vary significantly from state to state. As public interest in and access to teledermatology continue to grow, the future of teledermatology depends on the development of new technology as well as quality improvement strategies and the evolution of sustainable reimbursement policies.

  18. Globalisation and National Environmental Policy: Update and Overview

    NARCIS (Netherlands)

    F.H. Wijen (Frank); K. Zoeteman; J. Pieters (Jan); P. Seters (Paul)

    2012-01-01

    textabstractSUMMARY After outlining recent developments and the scope, target audience, and structure of the book, we review the literature on globalisation and environmental policy, especially the impact of globalisation on the environment and changes in environmental governance in relation to

  19. Aligning Teacher Preparation with Student Learning Standards. Policy Update. Vol. 22, No. 8

    Science.gov (United States)

    Hoss, Nickta; Eberle, Francis

    2015-01-01

    This Policy Update highlights the mismatch between the skills taught in many teacher preparation programs and those needed to help students achieve rigorous learning standards. State boards of education have a role to play here. They have authority over preparation program standards and approval processes, curriculum, teacher certification and…

  20. Dell Hymes and the New Language Policy Studies: Update from an Underdeveloped Country

    Science.gov (United States)

    McCarty, Teresa L.; Collins, James; Hopson, Rodney K.

    2011-01-01

    This essay updates Dell Hymes's "Report from an Underdeveloped Country" (the USA), positioning our analysis in the New Language Policy Studies. Taking up Hymes's call for comparative, critical studies of language use, we examine three cases, organizing our analysis around Hymes's questions: What "counts" as a language, a language problem, and…

  1. Oil and Gas Emergency Policy: Turkey 2013 update

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-06-01

    Oil has been one of the main energy sources in Turkey, accounting for some 28% of the country’s total primary energy supply (TPES) in 2011. Turkey’s oil demand slightly increased from 637 kb/d in 2003 to 670 kb/d in 2012, although it dropped down from 678 kb/d in 2009 to 650 kb/d in 2010. The transport sector accounted for half of total oil consumption in 2010. Domestic oil production is in decline in Turkey, amounting to 45 kb/d or about 6.7% of total consumption in 2012. In 2012, Turkey imported 712 kb/d, consisting of about 392 kb/d of crude oil and some 320 kb/d refined products. Around 39% of total crude oil imports came from Iran. Crude oil and petroleum products are mainly undertaken by tankers and two major international pipelines running through the country with a total annual handling capacity of 2.8 mb/d. In the country, there are four operational refineries with a total crude distillation capacity of around 610 kb/d. Turkey meets its 90-day stockholding obligation to the IEA by placing a minimum stockholding obligation on industry. Under the relevant acts, refineries and fuel distribution companies are obliged to hold at least 20 days of product stocks based on the average daily sales of previous year, while eligible consumers that use more than 20,000 tonnes annually are required to hold 15 days’ consumption of each type of liquid fuel. Turkey held some 61 million barrels of oil stocks at the end of January 2013, equating to 99 days of 2011 net-imports. Around 55% of total oil stocks are held in the form of crude oil. The use of emergency oil stocks is central to Turkey’s emergency response policy, which can be complemented by demand restraint measures. The share of natural gas in the country’s TPES significantly increased at 32% in 2011. Turkey’s gas demand significantly increased from 0.7 billion cubic meters (2 mcm/d) in 1987 to 45.3 bcm (124 mcm/d) in 2012, while indigenous natural gas production totalled some 0.63 bcm in the same year

  2. Oil and Gas Emergency Policy: China 2012 update

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-09-06

    Although coal is the dominant energy source in China, accounting for some 70% of the country's Total Energy Consumption (TEC) in 2009, oil and gas are also essential energy sources. Despite strong growth in consumption of oil, its share of TEC fell from 22% in 2000 to 18% in 2009, as coal use rose even faster to meet burgeoning demand for electricity. A strong policy push boosted natural gas supplies, particularly to residential customers, so that the share of natural gas doubled from 2% in 2000 to 4% in 2009. China is one of the important oil and natural gas producing counties in the world. In 2010, China's crude oil production exceeded 4 million barrels per day (mb/d). However, with strong and sustained economic growth, its demand for oil has also increased, from 4.6 mb/d in 2000 to over 8 mb/d in 2009. In the New Policy Scenario (NPS) of the IEA World Energy Outlook (WEO) 2011, China's primary oil demand rises to 12.2 mb/d in 2020. Although China is now the world's fifth largest oil producer, the country has been a net oil importer since 1993. In 2011, China imported over 5 mb/d of crude oil, accounting for about 54% of its total demand. More than 50% of the total crude oil imports came from counties of the Middle East. To prevent a potential shock to the economy caused by an oil supply disruption, the Chinese government has been steadily pushing building an oil stock reserve system. China has completed four stockpiling facilities with a capacity of around 103 mb in the first phase of its Strategic Petroleum Reserve (SPR) plan, and has begun construction of its second phase, which comprises eight storage sites that will reportedly have a combined capacity of around 207 mb. Among them, two sites were completed in the second half of 2011 and the Tianjin site is reportedly set to be completed in 2012. According to unofficial reports, the remaining four SPR-II sites are expected to become operational by 2013. The third phase is expected to boost

  3. Oil and Gas Emergency Policy: India 2007 update

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    With almost 1.1 billion inhabitants, India is the second most populous country in the world and the seventh-largest country by geographical area. In 2005, India’s GDP was about USD 644 billion. In terms of purchasing power parity (PPP)21, GDP stood at USD 3 362 which makes it the fourth-largest economy in the world (after the United States, China and Japan). Per capita income in PPP terms is around USD 3 582, about one-tenth of the OECD average. GDP growth in 2005 was 9.2%. India has about 5.6 billion barrels of proven oil reserves (January 2007). The combination of rising oil consumption and fairly stable production levels leaves India increasingly dependent on imports to meet consumption needs; most of these imports are coming from the Middle East. In 2006, the country produced an average of 792 kb/d of total oil liquids, of which 87% (687 kb/d) was crude oil. During 2006, India’s demand for oil reached 2.64 mb/d. In 2004, India decided to build a strategic petroleum reserve (SPR) in a phased manner. The work on the first phase started in 2007, with invitations for tender for the construction of rock caverns with a capacity of some 37 mb (5 Mt), which equates to 20 days of net imports or 15 days of consumption in 2005. The work is planned to be fi nished in 2010, after which the rock caverns will begin to be filled. A second phase is projected (but not yet scheduled), which would expand the storage capacity to 45 days of consumption (roughly 110 mb or 15 Mt). The Integrated Energy Policy of 2006 states that the effectiveness of the reserves can be increased through co-operative operation with the reserves of other countries, such as IEA member countries.

  4. On osp(2 | 2) -relative cohomology of the Lie superalgebra of contact vector fields and deformations

    Science.gov (United States)

    Nizar, Ben Fraj; Abdaoui, Meher; Hamza, Raouafi

    2018-02-01

    We consider the 1 | 2-dimensional real superspace R 1 | 2 endowed with its standard contact structure defined by the 1-form α. The conformal Lie superalgebra K(2) acts on R 1 | 2 as the Lie superalgebra of contact vector fields; it contains the Möbius superalgebra osp(2 | 2) . We classify osp(2 | 2) -invariant superskew-symmetric binary differential operators from K(2) ∧ K(2) to Dλ,μ vanishing on osp(2 | 2) , where Dλ,μ is the superspace of linear differential operators between the superspaces of weighted densities. This result allows us to compute the second differential osp(2 | 2) -relative cohomology of K(2) with coefficients in Dλ,μ. We study generic formal osp(2 | 2) -trivial deformations of the K(2) -module structure on the direct sum of the superspaces of weighted densities. This work is the simplest superization of a result by Bouarroudj (2007).

  5. Oil and Gas Emergency Policy: Japan 2013 update

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-06-01

    (before the March 2011 earthquake) to 22% in 2011, due to growing demand from the electricity generation sector. Japan’s demand for natural gas steadily increased from some 26 billion cubic meters (71 mcm/d) in 1980 to around 109 bcm (298.6 mcm/d) in 2010, to 124 bcm (340 mcm/d) in 2012. Japan’s domestic natural gas production is limited – with production of around 3.3 bcm in 2012. Natural gas supply sources to the country are well diversified. In 2011, Malaysia was the largest supplier, representing 18% of total imports. As Japan has no cross border pipelines, the country imported natural gas through 31 LNG terminals with around 10 bcm of natural gas storage capacity. Key elements of Japan’s overall gas security policy are diversifying its long-term supply contract portfolio, ensuring flexibility of increasing imports in times of an emergency in long term contracts, and using voluntary commercial LNG stocks in industry. Even though industry is not obliged to hold any emergency gas stocks, industry has commercial stocks equivalent to about 20 to 30 days of consumption. There is no single transmission operator in the country as the trunk line networks have developed separately around LNG terminals and they are not necessarily connected to each other. Each gas company is asked to ensure its natural gas supply to its distribution area.

  6. Oral Immunization with OspC Does Not Prevent Tick-Borne Borrelia burgdorferi Infection.

    Science.gov (United States)

    Melo, Rita; Richer, Luciana; Johnson, Daniel L; Gomes-Solecki, Maria

    2016-01-01

    Oral vaccination strategies are of interest to prevent transmission of Lyme disease as they can be used to deliver vaccines to humans, pets, and to natural wildlife reservoir hosts of Borrelia burgdorferi. We developed a number of oral vaccines based in E. coli expressing recombinant OspC type K, OspB, BBK32 from B. burgdorferi, and Salp25, Salp15 from Ixodes scapularis. Of the five immunogenic candidates only OspC induced significant levels of antigen-specific IgG and IgA when administered to mice via the oral route. Antibodies to OspC did not prevent dissemination of B. burgdorferi as determined by the presence of spirochetes in ear, heart and bladder tissues four weeks after challenge. Next generation sequencing of genomic DNA from ticks identified multiple phyletic types of B. burgdorferi OspC (A, D, E, F, I, J, K, M, Q, T, X) in nymphs that engorged on vaccinated mice. PCR amplification of OspC types A and K from flat and engorged nymphal ticks, and from heart and bladder tissues collected after challenge confirmed sequencing analysis. Quantification of spirochete growth in a borreliacidal assay shows that both types of spirochetes (A and K) survived in the presence of OspC-K specific serum whereas the spirochetes were killed by OspA specific serum. We show that oral vaccination of C3H-HeN mice with OspC-K induced significant levels of antigen-specific IgG. However, these serologic antibodies did not protect mice from infection with B. burgdorferi expressing homologous or heterologous types of OspC after tick challenge.

  7. CERN’s Computing rules updated to include policy for control systems

    CERN Document Server

    IT Department

    2008-01-01

    The use of CERN’s computing facilities is governed by rules defined in Operational Circular No. 5 and its subsidiary rules of use. These rules are available from the web site http://cern.ch/ComputingRules. Please note that the subsidiary rules for Internet/Network use have been updated to include a requirement that control systems comply with the CNIC(Computing and Network Infrastructure for Control) Security Policy. The security policy for control systems, which was approved earlier this year, can be accessed at https://edms.cern.ch/document/584092 IT Department

  8. The impact of marijuana policies on youth: clinical, research, and legal update.

    Science.gov (United States)

    Ammerman, Seth; Ryan, Sheryl; Adelman, William P

    2015-03-01

    This technical report updates the 2004 American Academy of Pediatrics technical report on the legalization of marijuana. Current epidemiology of marijuana use is presented, as are definitions and biology of marijuana compounds, side effects of marijuana use, and effects of use on adolescent brain development. Issues concerning medical marijuana specifically are also addressed. Concerning legalization of marijuana, 4 different approaches in the United States are discussed: legalization of marijuana solely for medical purposes, decriminalization of recreational use of marijuana, legalization of recreational use of marijuana, and criminal prosecution of recreational (and medical) use of marijuana. These approaches are compared, and the latest available data are presented to aid in forming public policy. The effects on youth of criminal penalties for marijuana use and possession are also addressed, as are the effects or potential effects of the other 3 policy approaches on adolescent marijuana use. Recommendations are included in the accompanying policy statement. Copyright © 2015 by the American Academy of Pediatrics.

  9. Structure constants of the OSP(1 vertical stroke 2) WZNW model

    Energy Technology Data Exchange (ETDEWEB)

    Hikida, Y.; Schomerus, V.

    2007-11-15

    We propose exact formulas for the 2- and 3-point functions of the WZNW model on the non-compact supergroup OSP(1 vertical stroke 2). Using the path integral approach that was recently developed in arXiv:0706.1030 we show how local correlation functions in the OSP(p vertical stroke 2) WZNW models can be obtained from those of N=p supersymmetric Liouville field theory for p=1,2. We then employ known results on correlators in N=1 Liouville theory to determine the structure constants of the OSP(1 vertical stroke 2) theory. (orig.)

  10. N-point and higher-genus osp(1|2) fusion

    International Nuclear Information System (INIS)

    Rasmussen, Joergen

    2003-01-01

    We study affine osp(1|2) fusion, the fusion in osp(1|2) conformal field theory, for example. Higher-point and higher-genus fusion is discussed. The fusion multiplicities are characterized as discretized volumes of certain convex polytopes, and are written explicitly as multiple sums measuring those volumes. We extend recent methods developed to treat affine su(2) fusion. They are based on the concept of generalized Berenstein-Zelevinsky triangles and virtual couplings. Higher-point tensor products of finite-dimensional irreducible osp(1|2) representations are also considered. The associated multiplicities are computed and written as multiple sums

  11. New Policy Conclusions from Starting Strong II: An Update on the OECD Early Childhood Policy Reviews

    Science.gov (United States)

    Bennett, John

    2006-01-01

    Since the start of the Organisation for Economic Co-operation and Development (OECD) thematic review of Early Childhood Education and Care (ECEC) Policy in 1998, some 20 countries across the world have been involved in the project. Recently the OECD has had a very successful launch of the report from the second round--Starting Strong II. This…

  12. December 2012 Policy Update: School Climate and Bully Prevention Trends State-by-State Assessment. School Climate Brief, Number 6

    Science.gov (United States)

    Bellizio, Dan

    2012-01-01

    This December 2012 Brief updates NSCC's 2011 report "State Policies on School Climate and Bully Prevention Efforts: Challenges and Opportunities for Deepening State Policy Support for Safe and Civil School"s (www.schoolclimate.org/climate/papers-briefs.php). This Brief provides a summary of State level: (1) anti-bullying legislation; (2)…

  13. Representation properties, Racah sum rule, and Biedenharn - Elliott identity for Uq(osp(1|2))

    International Nuclear Information System (INIS)

    Minnaert, P.; Mozrzymas, M.

    1998-01-01

    It is shown that the universal R matrix in the tensor product of two irreducible representation spaces of the quantum superalgebra U q (osp(1|2)) can be expressed by Clebsch - Gordan coefficients. The Racah sum rule satisfied by U q (osp(1|2)) Racah coefficients and 6-j symbols is derived from the properties of the universal R matrix in the tensor product of three representation spaces. Considering the tensor product of four irreducible representations, it is shown that Biedenharn - Elliott identity holds for U q (osp(1|2)) Racah coefficients and 6-j symbols. A recursion relation for U q (osp(1|2)) 6-j symbols is derived from the Biedenharn endash Elliott identity. copyright 1998 American Institute of Physics

  14. Application of Probabilistic Risk Assessment (PRA) During Conceptual Design for the NASA Orbital Space Plane (OSP)

    Science.gov (United States)

    Rogers, James H.; Safie, Fayssal M.; Stott, James E.; Lo, Yunnhon

    2004-01-01

    In order to meet the space transportation needs for a new century, America's National Aeronautics and Space Administration (NASA) has implemented an Integrated Space Transportation Plan to produce safe, economical, and reliable access to space. One near term objective of this initiative is the design and development of a next-generation vehicle and launch system that will transport crew and cargo to and from the International Space Station (ISS), the Orbital Space Plane (OSP). The OSP system is composed of a manned launch vehicle by an existing Evolved Expendable Launch Vehicle (EELV). The OSP will provide emergency crew rescue from the ISS by 2008, and provide crew and limited cargo transfer to and from the ISS by 2012. A key requirement is for the OSP to be safer and more reliable than the Soyuz and Space Shuttle, which currently provide these capabilities.

  15. Responding to the challenge of antimalarial drug resistance by routine monitoring to update national malaria treatment policies

    DEFF Research Database (Denmark)

    Vestergaard, Lasse S; Ringwald, Pascal

    2007-01-01

    additional information about changing patterns of resistance. However, some of the tests are technically demanding, and thus there is a need for more resources for training and capacity building in endemic countries to be able to adequately respond to the challenge of drug resistance....... of rational and updated malaria treatment policies, but defining and updating such policies requires a sufficient volume of high-quality drug-resistance data collected at national and regional levels. Three main tools are used for drug resistance monitoring, including therapeutic efficacy tests, in vitro...... tests, and analyses of molecular markers. Data obtained with the therapeutic efficacy test conducted according to the standard protocol of the World Health Organization are most useful for updating national treatment policies, while the in vitro test and molecular markers can provide important...

  16. Responding to the challenge of antimalarial drug resistance by routine monitoring to update national malaria treatment policies

    DEFF Research Database (Denmark)

    Vestergaard, Lasse S; Ringwald, Pascal

    2007-01-01

    Reduced sensitivity of Plasmodium falciparum to formerly recommended cheap and well-known antimalarial drugs places an increasing burden on malaria control programs and national health systems in endemic countries. The high costs of the new artemisinin-based combination treatments underline the use...... of rational and updated malaria treatment policies, but defining and updating such policies requires a sufficient volume of high-quality drug-resistance data collected at national and regional levels. Three main tools are used for drug resistance monitoring, including therapeutic efficacy tests, in vitro...... tests, and analyses of molecular markers. Data obtained with the therapeutic efficacy test conducted according to the standard protocol of the World Health Organization are most useful for updating national treatment policies, while the in vitro test and molecular markers can provide important...

  17. Medicare Part D research highlights and policy updates, 2013: impact and insights.

    Science.gov (United States)

    Stubbings, JoAnn; Lau, Denys T

    2013-04-01

    Since its implementation in 2006, Medicare Part D has evolved from a program that offered basic access to covered drugs for beneficiaries to one that has the potential to affect patient outcomes. The purpose of this article was to highlight key research findings on Medicare Part D published in 2012 and major public policy initiatives for Part D for 2013. PubMed/MEDLINE was searched for research studies on Part D published in 2012 in biomedical/scientific, peer-reviewed, English-language journals. For policy updates, sources included the Federal Register, the 2013 Final Call Letter, guidance from the Centers for Medicare and Medicaid Services, and 2012 publications on Part D policy identified in PubMed. Part D has been associated with higher medication use and lower out-of-pocket (OOP) costs of many long-term medications; however, differences within subgroups of beneficiaries have been observed. Studies on health outcomes have been inconclusive. Part D policy changes in 2013 have addressed problems with the benefit, namely coverage of benzodiazepines and barbiturates; reducing coinsurance in the coverage gap; reducing fraud, waste, and abuse; medication therapy management program standardization; and an expanded appeals process. Research continues to suggest that Part D is effective in increasing medication utilization and lowering OOP costs. Further work is needed to clarify the effects of Part D on nondrug health care service utilization and health outcomes. Policy changes for 2013 addressed specific improvements in the Medicare Part D benefit while potentially generating cost-savings for Medicare and Medicaid. Future challenges include alleviating access burden to medications during the phase-out of the coverage gap, minimizing disparities among Part D beneficiaries, and coordinating the Part D benefit with Medicare parts A and B via Medicare Accountable Care Organizations. A more integrated and coordinated Medicare benefit among all of its components would

  18. E2~Ub conjugates regulate the kinase activity of Shigella effector OspG during pathogenesis

    Energy Technology Data Exchange (ETDEWEB)

    Pruneda, Jonathan N. [Department of Biochemistry, University of Washington, Seattle WA USA; Smith, F. Donelson [Howard Hughes Medical Institute, Department of Pharmacology, University of Washington, Seattle WA USA; Daurie, Angela [Department of Microbiology and Immunology, Dalhousie University, Halifax NS Canada; Swaney, Danielle L. [Department of Genome Sciences, University of Washington, Seattle WA USA; Villén, Judit [Department of Genome Sciences, University of Washington, Seattle WA USA; Scott, John D. [Howard Hughes Medical Institute, Department of Pharmacology, University of Washington, Seattle WA USA; Stadnyk, Andrew W. [Department of Pediatrics, Dalhousie University, Halifax NS Canada; Le Trong, Isolde [Department of Biological Structure, University of Washington, Seattle WA USA; Stenkamp, Ronald E. [Department of Biochemistry, University of Washington, Seattle WA USA; Department of Biological Structure, University of Washington, Seattle WA USA; Klevit, Rachel E. [Department of Biochemistry, University of Washington, Seattle WA USA; Rohde, John R. [Department of Microbiology and Immunology, Dalhousie University, Halifax NS Canada; Brzovic, Peter S. [Department of Biochemistry, University of Washington, Seattle WA USA

    2014-01-20

    Pathogenic bacteria introduce effector proteins directly into the cytosol of eukaryotic cells to promote invasion and colonization. OspG, a Shigella spp. effector kinase, plays a role in this process by helping to suppress the host inflammatory response. OspG has been reported to bind host E2 ubiquitin-conjugating enzymes activated with ubiquitin (E2~Ub), a key enzyme complex in ubiquitin transfer pathways. A cocrystal structure of the OspG/UbcH5c~Ub complex reveals that complex formation has important ramifications for the activity of both OspG and the UbcH5c~Ub conjugate. OspG is a minimal kinase domain containing only essential elements required for catalysis. UbcH5c~Ub binding stabilizes an active conformation of the kinase, greatly enhancing OspG kinase activity. In contrast, interaction with OspG stabilizes an extended, less reactive form of UbcH5c~Ub. Recognizing conserved E2 features, OspG can interact with at least ten distinct human E2s~Ub. Mouse oral infection studies indicate that E2~Ub conjugates act as novel regulators of OspG effector kinase function in eukaryotic host cells.

  19. 3D printed porous polycaprolactone/oyster shell powder (PCL/OSP) scaffolds for bone tissue engineering

    Science.gov (United States)

    Luo, Wenfeng; Zhang, Shuangying; Lan, Yuewei; Huang, Chen; Wang, Chao; Lai, Xuexu; Chen, Hanwei; Ao, Ningjian

    2018-04-01

    In this work, oyster shell powder (OSP) was used as the bio-filler and combined with polycaprolactone (PCL) through melt blending methodology. The PCL and PCL/OSP scaffolds were prepared using additive manufacturing process. All the 3D printed scaffolds hold a highly porosity and interconnected pore structures. OSP particles are dispersed in the polymer matrix, which helped to improve the degree of crystallinity and mineralization ability of the scaffolds. There was no significant cytotoxicity of the prepared scaffolds towards MG-63 cells, and all the scaffolds showed a well ALP activity. Therefore, PCL/OSP scaffolds had a high potential to be employed in the bone tissue engineering.

  20. Evidence for frequent OspC gene transfer between Borrelia valaisiana sp. nov. and other Lyme disease spirochetes.

    Science.gov (United States)

    Wang, G; van Dam, A P; Dankert, J

    1999-08-15

    Molecular polymorphism of the ospC gene has been reported in Borrelia burgdorferi sensu stricto, Borrelia garinii and Borrelia afzelii, the spirochetes causing human Lyme borreliosis. To assess the genetic relationship between ospC genes from the recently described Borrelia valaisiana sp. nov. and other B. burgdorferi sensu lato species, the ospC genes from eight B. valaisiana isolates were amplified by PCR, cloned and sequenced. The ospC genes of three B. valaisiana isolates were identical, but clearly distinct from ospC genes from other Borrelia species. Four B. valaisiana isolates possessed ospC genes more related to those of B. garinii, and fell into a cluster representing B. garinii species in the phylogenetic tree. One isolate had an ospC gene encoding a protein identical to that of B. afzelii strain. Since five of the eight (62.5%) B. valaisiana isolates contained a gene highly homologous or even identical to ospC genes found among B. garinii and B. afzelii strains, our findings indicate that ospC gene transfer occurs between B. valaisiana and other Lyme disease spirochetes.

  1. The impact of marijuana policies on youth: clinical, research, and legal update.

    Science.gov (United States)

    2015-03-01

    This policy statement is an update of the American Academy of Pediatrics policy statement "Legalization of Marijuana: Potential Impact on Youth," published in 2004. Pediatricians have special expertise in the care of children and adolescents and may be called on to advise legislators about the potential impact of changes in the legal status of marijuana on adolescents. Parents also may look to pediatricians for advice as they consider whether to support state-level initiatives that propose to legalize the use of marijuana for medical and nonmedical purposes or to decriminalize the possession of small amounts of marijuana. This policy statement provides the position of the American Academy of Pediatrics on the issue of marijuana legalization. The accompanying technical report reviews what is currently known about the relationships of marijuana use with health and the developing brain and the legal status of marijuana and adolescents' use of marijuana to better understand how change in legal status might influence the degree of marijuana use by adolescents in the future. Copyright © 2015 by the American Academy of Pediatrics.

  2. Regulatory, policy and quality update for venous thromboembolism and stroke in United States hospitals.

    Science.gov (United States)

    Mahan, Charles E

    2012-10-01

    Stroke and venous thromboembolism (VTE) have a large impact on the United States (US) healthcare system. It is estimated that up to 1.7million new and recurrent stroke and VTE events are occurring in the US on an annual basis with the combined cost approaching over $200billion per year. A significant amount of stroke and VTE are preventable from appropriate antithrombotic use in at-risk patients and the Center for Medicaid and Medicare Services, the Joint Commission, the National Quality Forum and other key quality and regulatory entities have prioritized minimizing the impact of morbidity, mortality and avoidable costs related to these diseases. This review provides a brief history, overview, and update for the development of quality measures, quality systems, and regulatory and policy changes as related to stroke and VTE within the US healthcare system. Copyright © 2012 Elsevier Ltd. All rights reserved.

  3. Light-cone superspace BPS equations, and OSp(2, 2|16)

    Science.gov (United States)

    Hearin, Patrick

    The BPS bound is formulated in light-cone superspace for the N = 4 superYang-Mills theory. As a consequence of the superalgebra all momenta are shown to be expressed as quadratic forms in the relevant supertransformations, and these forms are used to derive the light-cone superspace BPS equations. Finally, the superfield expressions are expanded out to component form, and the Wu-Yang Monopole boosted to the infinite momentum frame is shown to be a solution. A possible non-linear realization of the OSp(2, 2|16) superconformal algebra is prescribed with methods used to derive the OSp(2, 2|8) theory in light-cone superspace. This theory is shown to have an inconsistency in the dynamical constraints which cannot be resolved, and no non-linear field theory can be consistently realized. This inconsistency is derived in the covariant OSp(2, 2|16) theory.

  4. Evidence for frequent OspC gene transfer between Borrelia valaisiana sp. nov. and other Lyme disease spirochetes

    NARCIS (Netherlands)

    Wang, G.; van Dam, A. P.; Dankert, J.

    1999-01-01

    Molecular polymorphism of the ospC gene has been reported in Borrelia burgdorferi sensu stricto, Borrelia garinii and Borrelia afzelii, the spirochetes causing human Lyme borreliosis. To assess the genetic relationship between ospC genes from the recently described Borrelia valaisiana sp. nov. and

  5. Public Policies for ICT Update In Business: Some Key Indicators for Spain in the European Area

    Directory of Open Access Journals (Sweden)

    Ana Lanero

    2011-08-01

    Full Text Available Purpose—Based on the new face of business in the twenty first century, this general review is aimed at analyzing the use of information and communication technologies (ICT as social technologies by Spanish enterprises in the European context, as a result of recent policy frameworks set at communitarian and national levels. Design/methodology/approach—The paper reviews the guidelines marked by European common policies with regards to ICT update in business, just as the translation of such standards in the Spanish area. From this framework, implications of ICT adoption in the social relationships with consumers, employees, business partners and public authorities are analyzed by providing some figures in the Spanish context in comparison with the European average.Findings—The analysis supports a positive effect of national policies on Spanish enterprises’ use of social technologies in the interactions with their internal and external stakeholders, while some differences can be reported attending size and sector criteria. In this respect, ICT penetration seems to be widespread in Spanish enterprises longer than ten employees, specially within informatics, telecommunications and audiovisuals, whereas automation of interactions is moderated in micro-enterprises in the manufacture, building, retailing, and transportation sectors.Research limitations/implications—The paper offers a general overview of the use of ICT as social technologies in Spanish enterprises based on public reports. However, further research should be oriented to analyze more in deep the impact of public policies on ICT adoption and usage in business, by explaining their determining factors and comparing different clusters of counties and major regions of the world.Practical implications—The analysis reported point to the need of reinforcing the Spanish positioning in the ICT European sector in the long term. In this sense, future policy measures should be devoted to

  6. Public Policies for ICT Update In Business: Some Key Indicators for Spain in the European Area

    Directory of Open Access Journals (Sweden)

    José Luis Vázquez

    2013-08-01

    Full Text Available Purpose—Based on the new face of business in the twenty first century, this general review is aimed at analyzing the use of information and communication technologies (ICT as social technologies by Spanish enterprises in the European context, as a result of recent policy frameworks set at communitarian and national levels.Design/methodology/approach—The paper reviews the guidelines marked by European common policies with regards to ICT update in business, just as the translation of such standards in the Spanish area. From this framework, implications of ICT adoption in the social relationships with consumers, employees, business partners and public authorities are analyzed by providing some figures in the Spanish context in comparison with the European average.Findings—The analysis supports a positive effect of national policies on Spanish enterprises’ use of social technologies in the interactions with their internal and external stakeholders, while some differences can be reported attending size and sector criteria. In this respect, ICT penetration seems to be widespread in Spanish enterprises longer than ten employees, specially within informatics, telecommunications and audiovisuals, whereas automation of interactions is moderated in micro-enterprises in the manufacture, building, retailing, and transportation sectors.Research limitations/implications—The paper offers a general overview of the use of ICT as social technologies in Spanish enterprises based on public reports. However, further research should be oriented to analyze more in deep the impact of public policies on ICT adoption and usage in business, by explaining their determining factors and comparing different clusters of counties and major regions of the world.Practical implications—The analysis reported point to the need of reinforcing the Spanish positioning in the ICT European sector in the long term. In this sense, future policy measures should be devoted to

  7. A Cholera Conjugate Vaccine Containing O-specific Polysaccharide (OSP of V. cholerae O1 Inaba and Recombinant Fragment of Tetanus Toxin Heavy Chain (OSP:rTTHc Induces Serum, Memory and Lamina Proprial Responses against OSP and Is Protective in Mice.

    Directory of Open Access Journals (Sweden)

    Md Abu Sayeed

    Full Text Available Vibrio cholerae is the cause of cholera, a severe watery diarrhea. Protection against cholera is serogroup specific. Serogroup specificity is defined by the O-specific polysaccharide (OSP component of lipopolysaccharide (LPS.Here we describe a conjugate vaccine for cholera prepared via squaric acid chemistry from the OSP of V. cholerae O1 Inaba strain PIC018 and a recombinant heavy chain fragment of tetanus toxin (OSP:rTTHc. We assessed a range of vaccine doses based on the OSP content of the vaccine (10-50 μg, vaccine compositions varying by molar loading ratio of OSP to rTTHc (3:1, 5:1, 10:1, effect of an adjuvant, and route of immunization.Immunized mice developed prominent anti-OSP and anti-TT serum IgG responses, as well as vibriocidal antibody and memory B cell responses following intramuscular or intradermal vaccination. Mice did not develop anti-squarate responses. Intestinal lamina proprial IgA responses targeting OSP occurred following intradermal vaccination. In general, we found comparable immune responses in mice immunized with these variations, although memory B cell and vibriocidal responses were blunted in mice receiving the highest dose of vaccine (50 μg. We found no appreciable change in immune responses when the conjugate vaccine was administered in the presence or absence of immunoadjuvant alum. Administration of OSP:rTTHc resulted in 55% protective efficacy in a mouse survival cholera challenge model.We report development of an Inaba OSP:rTTHc conjugate vaccine that induces memory responses and protection against cholera in mice. Development of an effective cholera conjugate vaccine that induces high level and long-term immune responses against OSP would be beneficial, especially in young children who respond poorly to polysaccharide antigens.

  8. Human rights principles in developing and updating policies and laws on mental health.

    Science.gov (United States)

    Schulze, M

    2016-01-01

    The World Health Organization's Mental Health Action Plan 2013-2020 stipulates human rights as a cross-cutting principle (WHO, 2013) and foresees global targets to update policies as well as mental health laws in line with international and regional human rights instruments. The international human rights agreements repeatedly refer to health, including mental health. The most pertinent provisions related to mental health are enshrined in the 2006 Convention on the Rights of Persons with Disabilities (CRPD), which sets out human rights in an accessible and inclusive fashion to ensure the equal participation of persons with disabilities. The inconclusive description of disability in the treaty overtly refers to 'mental impairment' as part of an explicitly evolving understanding of disability. This text sketches some of the underlying concepts as they apply to the realm of mental health: non-discrimination of persons with disabilities and measures that should be taken to ensure accessibility in a holistic understanding; removal of social and attitudinal barriers as much as communication and intellectual barriers but also institutional hurdles. The CRPD's paradigm shift away from framing disability mainly through deficits towards a social understanding of disability as the result of interaction and focusing on capacity is the core on which the provision of mental health services at community level to enable participation in society shall be ensured. Questions of capacity, also to make decisions and the possible need for support in so doing, are sketched out.

  9. Dunkl operators and a family of realizations of osp(1|2)

    DEFF Research Database (Denmark)

    de Bie, H.; Ørsted, B.; Somberg, P.

    2012-01-01

    In this paper, a family of radial deformations of the realization of the Lie superalgebra osp(1|2) in the theory of Dunkl operators is obtained. This leads to a Dirac operator depending on 3 parameters. Several function theoretical aspects of this operator are studied, such as the associated...

  10. Magnetic charges in the AdS(4) superalgebra osp(4 vertical bar 2)

    NARCIS (Netherlands)

    Dibitetto, Giuseppe; Klemm, Dietmar

    2010-01-01

    We discuss the issue of how to include magnetic charges in the AdS(4) superalgebra osp(4 vertical bar 2). It is shown that the usual way of introducing a pseudoscalar central charge on the right hand side of the basic anticommutator does not work, because this breaks SO(2, 3) covariance. We propose

  11. Identification of a defined linear epitope in the OspA protein of the Lyme disease spirochetes that elicits bactericidal antibody responses: Implications for vaccine development.

    Science.gov (United States)

    Izac, Jerilyn R; Oliver, Lee D; Earnhart, Christopher G; Marconi, Richard T

    2017-05-31

    The lipoprotein OspA is produced by the Lyme disease spirochetes primarily in unfed ticks. OspA production is down-regulated by the blood meal and it is not produced in mammals except for possible transient production during late stage infection in patients with Lyme arthritis. Vaccination with OspA elicits antibody (Ab) that can target spirochetes in the tick midgut during feeding and inhibit transmission to mammals. OspA was the primary component of the human LYMErix™ vaccine. LYMErix™ was available from 1998 to 2002 but then pulled from the market due to declining sales as a result of unsubstantiated concerns about vaccination induced adverse events and poor efficacy. It was postulated that a segment of OspA that shares sequence similarity with a region in human LFA-1 and may trigger putative autoimmune events. While evidence supporting such a link has not been demonstrated, most efforts to move forward with OspA as a vaccine component have sought to eliminate this region of concern. Here we identify an OspA linear epitope localized within OspA amino acid residues 221-240 (OspA 221-240 ) that lacks the OspA region suggested to elicit autoimmunity. A peptide consisting of residues 221-240 was immunogenic in mice. Ab raised against OspA 221-240 peptide surface labeled B. burgdorferi in IFAs and displayed potent Ab mediated-complement dependent bactericidal activity. BLAST analyses identified several variants of OspA 221-240 and a closely related sequence in OspB. It is our hypothesis that integration of the OspA 221-240 epitope into a multivalent-OspC based chimeric epitope based vaccine antigen (chimeritope) could result in a subunit vaccine that protects against Lyme disease through synergistic mechanisms. Copyright © 2017. Published by Elsevier Ltd.

  12. Piranti Lunak Pengujian Struktur Matematika Grup, Ring, Field Berbasis Osp (Open Source Program

    Directory of Open Access Journals (Sweden)

    Ngarap Im Manik

    2014-06-01

    Full Text Available This design of a computer software is a development and continuation of the software made on the previous research (2009/2010. However, this further research developed and expanded the scopes of testing more on the Siclic Group, Isomorphism Group, Semi Group, Sub Group and Abelian Group, Factor Ring, Sub Ring and Polynomial Ring; developed on the OSP (Open Source Program-based. The software was developed using the OSP-based language programming, such Java, so it is open and free to use for its users. This research succeeded to develop an open source software of Java program that can be used for testing specific mathematical Groups, such Ciclic Group, Isomorphism Group, Semi Group, Sub Group and Abelian Group, and Rings, Commutative Ring, Division Ring, Ideal Sub Ring, Ring Homomorphism, Ring Epimorphism and Fields. By the results, the software developed was able to test as same as the results from manual testing.

  13. Finite-size effects in the spectrum of the OSp (3 | 2) superspin chain

    Science.gov (United States)

    Frahm, Holger; Martins, Márcio J.

    2015-05-01

    The low energy spectrum of a spin chain with OSp (3 | 2) supergroup symmetry is studied based on the Bethe ansatz solution of the related vertex model. This model is a lattice realization of intersecting loops in two dimensions with loop fugacity z = 1 which provides a framework to study the critical properties of the unusual low temperature Goldstone phase of the O (N) sigma model for N = 1 in the context of an integrable model. Our finite-size analysis provides strong evidence for the existence of continua of scaling dimensions, the lowest of them starting at the ground state. Based on our data we conjecture that the so-called watermelon correlation functions decay logarithmically with exponents related to the quadratic Casimir operator of OSp (3 | 2). The presence of a continuous spectrum is not affected by a change to the boundary conditions although the density of states in the continua appears to be modified.

  14. Finite-size effects in the spectrum of the OSp(3|2 superspin chain

    Directory of Open Access Journals (Sweden)

    Holger Frahm

    2015-05-01

    Full Text Available The low energy spectrum of a spin chain with OSp(3|2 supergroup symmetry is studied based on the Bethe ansatz solution of the related vertex model. This model is a lattice realization of intersecting loops in two dimensions with loop fugacity z=1 which provides a framework to study the critical properties of the unusual low temperature Goldstone phase of the O(N sigma model for N=1 in the context of an integrable model. Our finite-size analysis provides strong evidence for the existence of continua of scaling dimensions, the lowest of them starting at the ground state. Based on our data we conjecture that the so-called watermelon correlation functions decay logarithmically with exponents related to the quadratic Casimir operator of OSp(3|2. The presence of a continuous spectrum is not affected by a change to the boundary conditions although the density of states in the continua appears to be modified.

  15. Inspection activities of other strategic points (OSPs) at Rokkasho Reprocessing Plant

    International Nuclear Information System (INIS)

    Kaifuki, Yukinobu; Ebata, Takashi; Nakano, Sadayuki; Fujimaki, Kazunori

    2008-01-01

    At Rokkasho Reprocessing Plant (RRP), Active Test (AT) using actual spent fuels for the final confirmation of the equipment and the system has been performed since March 31, 2006 toward the commercial operation. The safeguards inspection during AT is required in the same manner as commercial operation condition because plutonium is handled. In RRP automated verification systems are established by using unattended verification systems including a number of process monitoring systems along with main plutonium handling process from the spent fuel storage until the MOX product storages. Even under the modernized safeguards, inspection activities at Other Strategic Points (OSPs) are required to confirm plant status in accordance with requirements of the IAEA safeguards criteria. This paper presents procedures and inspection activities at OSPs which has been implemented in RRP since start of AT. (author)

  16. Conflicts of Interest in Clinical Guidelines: Update of U.S. Preventive Services Task Force Policies and Procedures.

    Science.gov (United States)

    Ngo-Metzger, Quyen; Moyer, Virginia; Grossman, David; Ebell, Mark; Woo, Meghan; Miller, Therese; Brummer, Tana; Chowdhury, Joya; Kato, Elisabeth; Siu, Albert; Phillips, William; Davidson, Karina; Phipps, Maureen; Bibbins-Domingo, Kirsten

    2018-01-01

    The U.S. Preventive Services Task Force (USPSTF) provides independent, objective, and scientifically rigorous recommendations for clinical preventive services. A primary concern is to avoid even the appearance of members having special interests that might influence their ability to judge evidence and formulate unbiased recommendations. The conflicts of interest policy for the USPSTF is described, as is the formal process by which best practices were incorporated to update the policy. The USPSTF performed a literature review, conducted key informant interviews, and reviewed conflicts of interest policies of ten similar organizations. Important findings included transparency and public accessibility; full disclosure of financial relationships; disclosure of non-financial relationships (that create the potential for bias and compromise a member's objective judgment); disclosure of family members' conflicts of interests; and establishment of appropriate reporting periods. Controversies in best practices include the threshold of financial disclosures, ease of access to conflicts of interest policies and declarations, vague definition of non-financial biases, and request for family members' conflicts of interests (particularly those that are non-financial in nature). The USPSTF conflicts of interest policy includes disclosures for immediate family members, a clear non-financial conflicts of interest definition, long look-back period and application of the policy to prospective members. Conflicts of interest is solicited from all members every 4 months, formally reviewed, adjudicated, and made publicly available. The USPSTF conflicts of interest policy is publicly available as part of the USPSTF Procedure Manual. A continuous improvement process can be applied to conflicts of interest policies to enhance public trust in members of panels, such as the USPSTF, that produce clinical guidelines and recommendations. Copyright © 2018 American Journal of Preventive Medicine

  17. The Position of His-Tag in Recombinant OspC and Application of Various Adjuvants Affects the Intensity and Quality of Specific Antibody Response after Immunization of Experimental Mice.

    Directory of Open Access Journals (Sweden)

    Michal Krupka

    Full Text Available Lyme disease, Borrelia burgdorferi-caused infection, if not recognized and appropriately treated by antibiotics, may lead to chronic complications, thus stressing the need for protective vaccine development. The immune protection is mediated by phagocytic cells and by Borrelia-specific complement-activating antibodies, associated with the Th1 immune response. Surface antigen OspC is involved in Borrelia spreading through the host body. Previously we reported that recombinant histidine tagged (His-tag OspC (rOspC could be attached onto liposome surfaces by metallochelation. Here we report that levels of OspC-specific antibodies vary substantially depending upon whether rOspC possesses an N' or C' terminal His-tag. This is the case in mice immunized: (a with rOspC proteoliposomes containing adjuvants MPLA or non-pyrogenic MDP analogue MT06; (b with free rOspC and Montanide PET GEL A; (c with free rOspC and alum; or (d with adjuvant-free rOspC. Stronger responses are noted with all N'-terminal His-tag rOspC formulations. OspC-specific Th1-type antibodies predominate post-immunization with rOspC proteoliposomes formulated with MPLA or MT06 adjuvants. Further analyses confirmed that the structural features of soluble N' and C' terminal His-tag rOspC and respective rOspC proteoliposomes are similar including their thermal stabilities at physiological temperatures. On the other hand, a change in the position of the rOspC His-tag from N' to C' terminal appears to affect substantially the immunogenicity of rOspC arguably due to steric hindrance of OspC epitopes by the C' terminal His-tag itself and not due to differences in overall conformations induced by changes in the His-tag position in rOspC variants.

  18. Conformal primaries of $OSp(8/4,R)$ and BPS states in $AdS_{4}$

    CERN Document Server

    Ferrara, Sergio; Ferrara, Sergio; Sokatchev, Emery

    2000-01-01

    We derive short UIR's of the OSp(8/4,R) superalgebra of 3d N=8 superconformalfield theories by the requirement that the highest weight states areannihilated by a subset of the super-Poincare odd generators. We then find asuperfield realization of these BPS saturated UIR's as "composite operators" ofthe two basic ultrashort "supersingleton" multiplets. These representations arethe AdS4 analogue of BPS states preserving different fractions of supersymmetryand are therefore suitable to classify perturbative and non-perturbativeexcitations of M-theory compactifications.

  19. The universal Racah-Wigner symbol for Uq(osp(1|2))

    International Nuclear Information System (INIS)

    Pawelkiewicz, Michal; Schomerus, Volker; Suchanek, Paulina; Wroclaw Univ.

    2013-10-01

    We propose a new and elegant formula for the Racah-Wigner symbol of self-dual continuous series of representations of U q (osp(1 vertical stroke 2)). It describes the entire fusing matrix for both NS and R sector of N=1 supersymmetric Liouville field theory. In the NS sector, our formula is related to an expression derived in an earlier paper (L. Hadaz, M. Pawelkiewicz, and V. Schomerus, arXiv:1305.4596[hep-th]). Through analytic continuation in the spin variables, our universal expression reproduces known formulas for the Racah-Wigner coefficients of finite dimensional representations.

  20. The reliability and predictive validity of a sixth-semester OSPE in conservative dentistry regarding performance on the state examination

    Directory of Open Access Journals (Sweden)

    Petko, Petkov

    2017-02-01

    Full Text Available Introduction: The aim of this study was to ascertain whether the testing format of an OSPE (Objective Structured Practical Examination in conservative dentistry (sixth semester predicts the scores on the practical section of the state examination (11 semester in the same subject. Taking general student profiles into consideration (score on the school-leaving exam [Abitur], score on the preliminary exam in dental medicine [Physikum], length of university study, cohorts, and sex, we also investigated if any correlations or differences exist in regard to the total and partial scores on the OSPE and the corresponding state examination.Methods: Within the scope of this longitudinal retrospective study, exam-specific data spanning 11 semesters for dental students (N=223 in Frankfurt am Main were collected and analyzed. Statistical analysis was carried out by calculating Spearman rank correlations, partial correlations, Pearson’s correlation coefficients, and multiple regressions (SPSS Statistics 21, IBM Corporation, New York.Results: The results show that the OSPE (Cronbach’s α=.87 correlates with level of success on the practical section of the state exam in conservative dentistry (=.01, =.17. Length of university study also emerged to correlate significantly with the state exam score (=.001, =.23. Together, these two variables contribute significantly to predicting the state exam score (=.001, =.076. This was seen extensively among female students. It was also discovered that these female students had higher school-leaving exam scores than male students (=6.09, =.01, =.027, and that a significant correlation between scores on the Physikum (preliminary exam in dental medicine and OSPE scores existed only for male students (=.17, =.01.Conclusion: This study was able to demonstrate the predictive effect of a clinical OSPE regarding scores achieved on the state exam. Taking the limitations of this study into account, we are able to recommend using

  1. American Society of Clinical Oncology Policy Statement Update: Genetic and Genomic Testing for Cancer Susceptibility.

    Science.gov (United States)

    Robson, Mark E; Bradbury, Angela R; Arun, Banu; Domchek, Susan M; Ford, James M; Hampel, Heather L; Lipkin, Stephen M; Syngal, Sapna; Wollins, Dana S; Lindor, Noralane M

    2015-11-01

    The American Society of Clinical Oncology (ASCO) has long affirmed that the recognition and management of individuals with an inherited susceptibility to cancer are core elements of oncology care. ASCO released its first statement on genetic testing in 1996 and updated that statement in 2003 and 2010 in response to developments in the field. In 2014, the Cancer Prevention and Ethics Committees of ASCO commissioned another update to reflect the impact of advances in this area on oncology practice. In particular, there was an interest in addressing the opportunities and challenges arising from the application of massively parallel sequencing-also known as next-generation sequencing-to cancer susceptibility testing. This technology introduces a new level of complexity into the practice of cancer risk assessment and management, requiring renewed effort on the part of ASCO to ensure that those providing care to patients with cancer receive the necessary education to use this new technology in the most effective, beneficial manner. The purpose of this statement is to explore the challenges of new and emerging technologies in cancer genetics and provide recommendations to ensure their optimal deployment in oncology practice. Specifically, the statement makes recommendations in the following areas: germline implications of somatic mutation profiling, multigene panel testing for cancer susceptibility, quality assurance in genetic testing, education of oncology professionals, and access to cancer genetic services. © 2015 by American Society of Clinical Oncology.

  2. The exact solution and the finite-size behaviour of the Osp(1vertical stroke 2)-invariant spin chain

    International Nuclear Information System (INIS)

    Martins, M.J.

    1995-01-01

    We have solved exactly the Osp(1vertical stroke 2) spin chain by the Bethe ansatz approach. Our solution is based on an equivalence between the Osp(1vertical stroke 2) chain and a certain special limit of the Izergin-Korepin vertex model. The completeness of the Bethe ansatz equations is discussed for a system with four sites and the appearance of special string structures is noted. The Bethe ansatz presents an important phase factor which distinguishes the even and odd sectors of the theory. The finite-size properties are governed by a conformal field theory with central charge c=1. (orig.)

  3. The IEEE-SA patent policy update under the lens of EU competition law

    NARCIS (Netherlands)

    Kanevskaia, Olia; Zingales, Nicolo

    2016-01-01

    In 2015, the Institute of Electrical and Electronics Engineers (IEEE) Standardization Association made some controversial changes to its patent policy. The changes include a recommended method of calculation of FRAND royalty rates, and a request to members holding a standard-essential patent to

  4. ESSA and Students with Disabilities. Policy Update. Vol. 23, No. 20

    Science.gov (United States)

    Parsi, Ace; Casey, Meghan

    2016-01-01

    The nation's six million students with disabilities have graduation rates nearly 25 percent lower than their general education peers and significantly lower postsecondary enrollment and completion rates. For the last decade and a half, state policy leaders have decried No Child Left Behind's lack of flexibility and one-size-fits-all design for…

  5. Addressing the Policy-bias of Q-learning by Repeating Updates

    NARCIS (Netherlands)

    S. Abdallah (Sherief); M. Kaisers (Michael); T. Ito; C.M. Jonker (Catholijn); M. Gini; O. Shehory (Onn)

    2013-01-01

    htmlabstractQ-learning is a very popular reinforcement learning algorithm being proven to converge to optimal policies in Markov decision processes. However, Q-learning shows artifacts in non-stationary environments, e.g., the probability of playing the optimal action may decrease if Q-values

  6. Complex structure of OspI and Ubc13: the molecular basis of Ubc13 deamidation and convergence of bacterial and host E2 recognition.

    Directory of Open Access Journals (Sweden)

    Panhan Fu

    Full Text Available Ubc13 is an important ubiquitin-conjugating (E2 enzyme in the NF-κB signaling pathway. The Shigella effector OspI targets Ubc13 and deamidates Gln100 of Ubc13 to a glutamic acid residue, leading to the inhibition of host inflammatory responses. Here we report the crystal structure of the OspI-Ubc13 complex at 2.3 Å resolution. The structure reveals that OspI uses two differently charged regions to extensively interact with the α1 helix, L1 loop and L2 loop of Ubc13. The Gln100 residue is bound within the hydrophilic catalytic pocket of OspI. A comparison between Ubc13-bound and wild-type free OspI structures revealed that Ubc13 binding induces notable structural reassembly of the catalytic pocket, suggesting that substrate binding might be involved in the catalysis of OspI. The OspI-binding sites in Ubc13 largely overlap with the binding residues for host ubiquitin E3 ligases and a deubiquitinating enzyme, which suggests that the bacterial effector and host proteins exploit the same surface on Ubc13 for specific recognition. Biochemical results indicate that both of the differently charged regions in OspI are important for the interaction with Ubc13, and the specificity determinants in Ubc13 for OspI recognition reside in the distinct residues in the α1 helix and L2 region. Our study reveals the molecular basis of Ubc13 deamidation by OspI, as well as a convergence of E2 recognition by bacterial and host proteins.

  7. The OSp(32 vertical stroke 1) versus OSp(8 vertical stroke 2) supersymmetric M-brane action from self-dual (2,2) strings

    International Nuclear Information System (INIS)

    Ketov, S.V.

    1996-09-01

    Taking the (2,2) strings as a starting point, we discuss the equivalent self-dual field theories and analyze their symmetry structure in 2+2 dimensions from the viewpoint of string/membrane unification. Requiring the 'Lorentz' invariance and supersymmetry in the (2,2) string target space leads to an extension of the (2,2) string theory to a theory of 2+2 dimensional supermembranes (M-branes) propagating in a higher dimensional target space. The origin of the hidden target space dimensions of the M-brane is related to the maximally extended supersymmetry implied by the 'Lorentz' covariance and dimensional reasons. The Kaehler-Chern-Simons-type action describing the self-dual gravity in 2+2 dimensions is proposed. Its maximal supersymmetrization (of the Green-Schwarz-type) naturally leads to the 2+10 (or higher) dimensions for the M-brane target space. The proposed OSp(32 vertical stroke 1) supersymmetric action gives the pre-geometrical description of M-branes, which may be useful for a fundamental formulation of F and M theory. (orig.)

  8. Biofuel developments in Mozambique. Update and analysis of policy, potential and reality

    International Nuclear Information System (INIS)

    Schut, Marc; Slingerland, Maja; Locke, Anna

    2010-01-01

    Climate change, rising oil prices and concerns about future energy supplies have contributed to a growing interest in using biomass for energy purposes. Several studies have highlighted the biophysical potential of biofuel production on the African continent, and analysts see Mozambique as one of the most promising African countries. Favorable growing conditions and the availability of land, water and labor are mentioned as major drivers behind this potential. Moreover, the potential of biofuel production to generate socio-economic benefits is reflected in the government's policy objectives for the development of the sector, such as reducing fuel import dependency and creating rural employment. This article provides an overview of biofuel developments in Mozambique and explores to what extent reality matches the suggested potential in the country. We conclude that biofuel developments mainly take place in areas near good infrastructure, processing and storage facilities, where there is (skilled) labor available, and access to services and goods. Moreover, our analysis shows the need to timely harmonize current trends in biofuel developments with the government's policy objectives as the majority of existing and planned projects are not focusing on remote rural areas, and - in absence of domestic markets - principally target external markets. (author)

  9. The need for a single cleaning standard for OEM and OSP fiber optic connections

    Science.gov (United States)

    Forrest, Edward J., Jr.; Blair, Paul

    2009-01-01

    Development of fiber optic communications networks has continued in virtually all geographies of the world. Some calculate that expansion in the USA alone will continue to 2025. After that time there will maintenance, upgrade, and replacement. While some nations are more advanced than others and some enterprises more sophisticated than others, the undeniable reality is that previous networks will, in some fashion or another, include fiber optics. The future need is for speed and reliable bandwidth: lots of it. Decisions will be made based on new concepts that will enable far more data at far faster rates than once considered feasible or necessary. As the consumer enters the market with newly engineered home entertainment systems, additional burdens will be placed on both OEM and OSP. These are not negative challenges, but rather indicators of a new generation of consumers with awareness and demand far more advanced any may have imagined just a few years ago.

  10. Zero curvature condition of OSp(2/2) and the associated supergravity theory

    International Nuclear Information System (INIS)

    Das, A.; Huang, W.J.; Roy, S.

    1992-01-01

    In this paper, the N = 2 fermionic extensions of the KdV equations are derived from the zero curvature condition associated with the graded Lie algebra of OSp(2/2). These equations lead to two bi-Hamiltonian systems, one of which is supersymmetric. The authors also derive the one-parameter family of N = 2 supersymmetric KdV equations without a bi-Hamiltonian structure in this approach. Following the authors' earlier proposal, the authors interpret the zero curvature conditions as a gauge anomaly equation which brings out the underlying current algebra for the corresponding 2D supergravity theory. This current algebra is then used to obtain the operator product expansions of various fields of this theory

  11. The Updated AGU Ethics Policy: Supporting Inclusive and Diverse Field and Lab Environments within the Geosciences.

    Science.gov (United States)

    Williams, B. M.; McPhaden, M. J.; Gundersen, L. C.

    2017-12-01

    The American Geophysical Union (AGU), a scientific society of >60,000 members worldwide, has established a set of scientific integrity and professional ethics guidelines for the actions of its members, for the governance of the union in its internal activities, and for the operations and participation in its publications and scientific meetings. More recently AGU has undertaken actions to help address the issue of harassment in the sciences and other work climate issues; and, where applied more broadly as a code of standard behavior, will help address tangential issues of diversity and inclusion. This presentation will highlight the proposed policy changes and additional resources now in place, as they apply to field and lab environments. Progress to date and remaining challenges of this effort will be discussed, including AGU's work to provide additional program strength in the areas of Ethics, Diversity and Inclusion.

  12. Climate change policy initiatives. 1995/96 update. Volume II: selected non-iea countries

    International Nuclear Information System (INIS)

    1996-01-01

    This IEA study details in a standard format the actions that twenty non-IEA countries are taking under the United Nations Framework Convention on Climate Change. It provides information on the development of their national strategies to address greenhouse gas emissions, along with detailed data regarding such emissions from energy sources. The book summarises the positions of these countries in the international negotiations on the Convention, their efforts regarding emissions of CO 2 and other greenhouse gases, and their present and planned policies relevant to emissions from the energy sector. Key data on each country's energy production and use are given, along with tables showing recent trends (through 1993) in energy demand and energy-related CO 2 emissions. Most country profiles also include information on relevant national studies. (author)

  13. Global warming 2007. An update to global warming: the balance of evidence and its policy implications.

    Science.gov (United States)

    Keller, Charles F

    2007-03-09

    In the four years since my original review (Keller[25]; hereafter referred to as CFK03), research has clarified and strengthened our understanding of how humans are warming the planet. So many of the details highlighted in the IPCC's Third Assessment Report[21] and in CFK03 have been resolved that I expect many to be a bit overwhelmed, and I hope that, by treating just the most significant aspects of the research, this update may provide a road map through the expected maze of new information. In particular, while most of CFK03 remains current, there are important items that have changed: Most notable is the resolution of the conundrum that mid-tropospheric warming did not seem to match surface warming. Both satellite and radiosonde (balloon-borne sensors) data reduction showed little warming in the middle troposphere (4-8 km altitude). In the CFK03 I discussed potential solutions to this problem, but at that time there was no clear resolution. This problem has now been solved, and the middle troposphere is seen to be warming apace with the surface. There have also been advances in determinations of temperatures over the past 1,000 years showing a cooler Little Ice Age (LIA) but essentially the same warming during medieval times (not as large as recent warming). The recent uproar over the so-called "hockey stick" temperature determination is much overblown since at least seven other groups have made relatively independent determinations of northern hemisphere temperatures over the same time period and derived essentially the same results. They differ on how cold the LIA was but essentially agree with the Mann's hockey stick result that the Medieval Warm Period was not as warm as the last 25 years. The question of the sun's influence on climate continues to generate controversy. It appears there is a growing consensus that, while the sun was a major factor in earlier temperature variations, it is incapable of having caused observed warming in the past quarter

  14. New solutions of the Yang-Baxter equation based on root of 1 representations of the Para-Bose superalgebra Uq[osp(1/2)

    International Nuclear Information System (INIS)

    Palev, T.D.; Stoilova, N.I.

    1995-07-01

    New solutions of the quantum Yang-Baxter equation, depending in general on three arbitrary parameters, are written down. They are based on the root of unity representations of the quantum orthosymplectic superalgebra U q [osp(1/2)], which were found recently. Representations of the braid group B N are defined within any N th tensorial power of root of 1 U q [osp(1/2)] modules. (author). 40 refs

  15. "Alkohol und Nikotin" − Konzept und Evaluation eines interdisziplinären Wahlfachs mit OSPE im Studienabschnitt Medizin 1

    Directory of Open Access Journals (Sweden)

    Bergelt, Corinna

    2014-02-01

    Full Text Available [english] In the last decade, increasing interest has been paid to interdisciplinary and practical courses in the medical education in Germany. This report describes the implementation and outcome of a preclinical interdisciplinary elective course with a team-teaching concept developed by lecturers in medical psychology, anatomy, physiology and biochemistry. The practical orientation of the course led to the implementation of a final interdisciplinary OSPE to ensure fair consideration of the different disciplines involved in grading. Individual OSPE results correlate well with the fact that different skills are required in medical psychology compared to those required in anatomy, physiology and biochemistry. Student course evaluation and lecturers` experience indicate the success of this elective course. Its concept can be well adapted to other interdisciplinary courses.

  16. Demonstration of a New Smallsat Launch Vehicle: The Orbital/Suborbital Program (OSP) Space Launch Vehicle Inaugural Mission Results

    OpenAIRE

    Schoneman, Scott; Buckley, MAJ Steven; Stoller, MAJ George; Marina, CPT Luis; Morris, LT Christopher

    2000-01-01

    The United States Air Force and Orbital Sciences Corporation (Orbital) completed development and demonstration of a new low cost space launch vehicle for launching small satellites using surplus Minuteman II rocket motors melded with commercial launch vehicle technology. The Orbital Suborbital Program Space Launch Vehicle (OSPSLV, aka OSP Minotaur) successfully achieved all mission objectives with the inaugural launch into a 405 nm circular, 100 deg inclination orbit on 26 January, 2000. This...

  17. Borrelia burgdorferi outer surface protein C (OspC) binds complement component C4b and confers bloodstream survival.

    Science.gov (United States)

    Caine, Jennifer A; Lin, Yi-Pin; Kessler, Julie R; Sato, Hiromi; Leong, John M; Coburn, Jenifer

    2017-12-01

    Borrelia burgdorferi (Bb) is the causative agent of Lyme disease in the United States, a disease that can result in carditis, and chronic and debilitating arthritis and/or neurologic symptoms if left untreated. Bb survives in the midgut of the Ixodes scapularis tick, or within tissues of immunocompetent hosts. In the early stages of infection, the bacteria are present in the bloodstream where they must resist clearance by the innate immune system of the host. We have found a novel role for outer surface protein C (OspC) from B. burgdorferi and B. garinii in interactions with the complement component C4b and bloodstream survival in vivo. Our data show that OspC inhibits the classical and lectin complement pathways and competes with complement protein C2 for C4b binding. Resistance to complement is important for maintenance of the lifecycle of Bb, enabling survival of the pathogen within the host as well as in the midgut of a feeding tick when ospC expression is induced. © 2017 John Wiley & Sons Ltd.

  18. Future considerations for clinical dermatology in the setting of 21st century American policy reform: The Relative Value Scale Update Committee.

    Science.gov (United States)

    Barbieri, John S; Nguyen, Harrison P; Forman, Howard P; Bolognia, Jean L; Collins, Scott A B

    2018-04-01

    The American Medical Association-Specialty Society Relative Value Scale Update Committee, also known as the RUC, plays a critical role in assessing the relative value of physician services and procedures. This committee provides access for all physicians, including dermatologists, to the reimbursement process. Since the introduction of the Resource-Based Relative Value Scale by Medicare, the RUC has done important work to evaluate and refine reimbursement for physician services. The RUC recommendations have also led the Current Procedural Terminology (CPT) Editorial Panel to develop additional reimbursement codes as new procedures and services are developed. In this article (from the series Future Considerations for Clinical Dermatology in the Setting of 21st Century American Policy Reform), we will review the RUC, including its history and membership, the RUC update process, and a brief discussion of a few issues of particular importance to dermatologists. Copyright © 2017 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved.

  19. Targeting of chromatin readers: a novel strategy used by the Shigella flexneri virulence effector OspF to reprogram transcription

    Directory of Open Access Journals (Sweden)

    Habiba Harouz

    2014-12-01

    Full Text Available Shigella flexneri, a gram-negative bacterium responsible of bacillary dysentery, uses multiple strategies to overcome host immune defense. We have decrypted how this bacterium manipulates host-cell chromatin binders to take control of immune gene expression. We found that OspF, an injected virulence factor previously identified as a repressor of immune gene expression, targets the chromatin reader HP1γ. Heterochromatin Protein 1 family members specifically recognize and bind histone H3 methylated at Lys 9. Although initially identified as chromatin-associated transcriptional silencers in heterochromatin, their location in euchromatin indicates an active role in gene expression. Notably, HP1γ phosphorylation at Serine 83 defines a subpopulation exclusively located to euchromatin, targeted to the site of transcriptional elongation. We showed that OspF directly interacts with HP1γ, and causes HP1 dephosphorylation, suggesting a model in which this virulence effector “uses” HP1 proteins as beacons to target and repress immune gene expression (Harouz, et al. EMBO J (2014. OspF alters HP1γ phosphorylation mainly by inactivating the Erk-activated kinase MSK1, spotlighting it as a new HP1 kinase. In vivo, infectious stresses trigger HP1γ phosphorylation in the colon, principally in the lamina propria and the intestinal crypts. Several lines of evidence suggest that HP1 proteins are modified as extensively as histones, and decrypting the impact of these HP1 post-translational modifications on their transcriptional activities in vivo will be the next challenges to be taken up.

  20. The universal Racah-Wigner symbol for U{sub q}(osp(1 vertical stroke 2))

    Energy Technology Data Exchange (ETDEWEB)

    Pawelkiewicz, Michal; Schomerus, Volker [DESY Hamburg (Germany). Theory Group; Suchanek, Paulina [DESY Hamburg (Germany). Theory Group; Wroclaw Univ. (Poland). Inst. for Theoretical Physics

    2013-10-15

    We propose a new and elegant formula for the Racah-Wigner symbol of self-dual continuous series of representations of U{sub q}(osp(1 vertical stroke 2)). It describes the entire fusing matrix for both NS and R sector of N=1 supersymmetric Liouville field theory. In the NS sector, our formula is related to an expression derived in an earlier paper (L. Hadaz, M. Pawelkiewicz, and V. Schomerus, arXiv:1305.4596[hep-th]). Through analytic continuation in the spin variables, our universal expression reproduces known formulas for the Racah-Wigner coefficients of finite dimensional representations.

  1. On a possible algebra morphism of Uq[osp(1/2n)] onto the deformed oscillator algebra Wq(n)

    International Nuclear Information System (INIS)

    Palev, T.D.; Stoilova, N.I.

    1993-03-01

    We formulate a conjecture, stating that the algebra of n pairs of deformed Bose creation and annihilation operators is a factor-algebra of U q [osp(1/2n)], considered as a Hopf algebra, and prove it for n=2 case. To this end we show that for any value of qU q [osp(1/4)] can be viewed as a superalgebra, freely generated by two pairs B 1 ± , B 2 ± of deformed para-Bose operators. We write down all Hopf algebra relations, an analogue of the Cartan-Weyl basis, the ''commutation'' relations between the generators and a basis in U q [osp(1/2n)] entirely in terms of B 1 ± , B 2 ± . (author). 21 refs

  2. Biochemical and biophysical characterization of the major outer surface protein, OSP-A from North American and European isolates of Borrelia burgdorferi

    Energy Technology Data Exchange (ETDEWEB)

    McGrath, B.C.; Dunn, J.J. [Brookhaven National Lab., Upton, NY (United States); France, L.L. [Plum Island Animal Disease Center, Greenport, NY (United States); Jaing, W.; Polin, D.; Gorgone, G.; Luft, B.; Dykhuizen, D. [SUNY at Stony Brook, Stony Brook, NY (United States)

    1995-12-31

    Lyme borreliosis, caused by the spirochete Borrelia burgdorferi, is the most common vector-borne disease in North America and Western Europe. As the major delayed immune response in humans, a better understanding of the major outer surface lipoproteins OspA and OspB are of much interest. These proteins have been shown to exhibit three distinct phylogenetic genotypes based on their DNA sequences. This paper describes the cloning of genomic DNA for each variant and amplification of PCR. DNA sequence data was used to derive computer driven phylogenetic analysis and deduced amino acid sequences. Overproduction of variant OspAs was carried out in E. coli using a T7-based expression system. Circular dichroism and fluorescence studies was carried out on the recombinant B31 PspA yielding evidence supporting a B31 protein containing 11% alpha-helix, 34% antiparallel beta-sheet, 12% parallel beta sheet.

  3. NMR studies of Borrelia burgdorferi OspA, a 28 kDa protein containing a single-layer {beta}-sheet

    Energy Technology Data Exchange (ETDEWEB)

    Pham, Thuy-Nga; Koide, Shohei

    1998-05-15

    The crystal structure of outer surface protein A (OspA) from Borrelia burgdorferi contains a single-layer {beta}-sheet connecting the N- and C-terminal globular domains. The central {beta}-sheet consists largely of polar amino acids and it is solvent-exposed on both faces, which so far appears to be unique among known protein structures. We have accomplished nearly complete backbone H, C and N and C{sup ;}/H{sup {beta}} assignments of OspA (28 kDa) using standard triple resonance techniques without perdeuteration. This was made possible by recording spectra at a high temperature (45 {sup o}C ). The chemical shift index and {sup 15}N T{sub 1}/T{sub 2} ratios show that both the secondary structure and the global conformation of OspA in solution are similar to the crystal structure, suggesting that the unique central {beta}-sheet is fairly rigid.

  4. Analytical complements to the parity-independent Racah-Wigner calculus for the superalgebra osp(1/2). Part 1

    International Nuclear Information System (INIS)

    Brehamet, L.

    2006-01-01

    Essential simplifications are successfully carried out for all the phase factors occurring in various sum rules, formulas or expressions of mathematical tools, related to osp(1|2) parity-independent features. Another bringing-in lies in the introduction of a supertriangle Δ S in terms of integral parts, and of a symmetrical contraction phase factor g. From sometimes unusual techniques, new results are derived: a cyclic form of an identity between 3-j S symbols, intrinsic form of the irreducibility for any tensor operator, a linear identity between some special 6-j S symbols, a set of non-trivial zeros of 6-j S symbols, and--for the first time--explicit general analytical formulas for the 6-j S symbols. These latter are compact and given as a series over an integral index z in terms of Δ S and integral parts. A comparative synoptic of su(2) and osp(1|2) various formulas is supplied. New useful algebraic tables of boundary 6-j S symbols and those with one argument equal to 1 are listed

  5. Analytical complements to the parity-independent Racah-Wigner calculus for the superalgebra osp(1/2). Part 2. (9-jS symbols)

    International Nuclear Information System (INIS)

    Brehamet, L.

    2006-01-01

    An original method for defining 9-j S symbols for osp(1|2), directly in terms of parity-independent 6-j S symbols is developed, from both osp(1|2) Racah and Biedenharn-Elliott sum rules only. The important property of invariance under transposition is preserved. This method exhibits at the same time their definition and their permutational symmetries. Formulas of the six different 9-j S symbols with one argument zero are listed. In addition to the pseudo-orthogonality relation, various sum rules up to triple summations, analogous to those known for su(2), are also derived, the phase factors of which are given with the most compact form as possible, mainly in terms of integral parts. osp(1|2) analog of the famous Innes-Ufford identity is written down. Definition of mixed tensor operators is given, followed by the formula of its associated osp(1|2) tensorial permutation identity. Expressions for their reduced matrix elements in coupled basis are derived and explicited in terms of 9-j S symbols. After a detailed approach of the concept of a total super angular momentum J (1x2), examples of calculus with products of mixed tensor operators are presented, showing clearly the occurrence of 9-j S symbols in the study of reduced matrix elements problems

  6. Use of T7 RNA polymerase to direct expression of outer Surface Protein A (OspA) from the Lyme disease Spirochete, Borrelia burgdorferi

    Science.gov (United States)

    Dunn, John J.; Lade, Barbara N.

    1991-01-01

    The OspA gene from a North American strain of the Lyme disease Spirochete, Borrelia burgdorferi, was cloned under the control of transciption and translation signals from bacteriophage T7. Full-length OspA protein, a 273 amino acid (31kD) lipoprotein, is expressed poorly in Escherichia coli and is associated with the insoluble membrane fraction. In contrast, a truncated form of OspA lacking the amino-terminal signal sequence which normally would direct localization of the protein to the outer membrane is expressed at very high levels (less than or equal to 100 mg/liter) and is soluble. The truncated protein was purified to homogeneity and is being tested to see if it will be useful as an immunogen in a vaccine against Lyme disease. Circular dichroism and fluorescence spectroscopy was used to characterize the secondary structure and study conformational changes in the protein. Studies underway with other surface proteins from B burgdorferi and a related spirochete, B. hermsii, which causes relapsing fever, leads us to conclude that a strategy similar to that used to express the truncated OspA can provide a facile method for producing variations of Borrelia lipoproteins which are highly expressed in E. coli and soluble without exposure to detergents.

  7. Childhood Obesity and Nutrition Issues in the United States: An Update on School-based Policies and Practices. Education Policy Brief, Volume 10, Number 1, Spring 2012

    Science.gov (United States)

    Spradlin, Terry; Gard, Greta; Huang, Vivian; Kopp, Beth; Malik, Alanna

    2012-01-01

    This Education Policy Brief examines the latest research and statistics regarding childhood obesity. In addition to providing an overview of current trends and effects of childhood obesity, this brief considers the reasons for the increase in obesity rates among children, as well as the latest federal and state initiatives created to combat…

  8. Induced (N,0) supergravity as a constrained Osp(N|2) WZWN model and its effective action

    CERN Document Server

    Delius, G W; van Nieuwenhuizen, P

    1993-01-01

    A chiral $(N,0) $ supergravity theory in d=2 dimensions for any $N$ and its induced action can be obtained by constraining the currents of an Osp(N$|$2) WZWN model. The underlying symmetry algebras are the nonlinear SO(N) superconformal algebras of Knizhnik and Bershadsky. The case $N=3$ is worked out in detail. We show that by adding quantum corrections to the classical transformation rules, the gauge algebra on gauge fields and currents closes. Integrability conditions on Ward identities are derived. The effective action is computed at one loop. It is finite, and can be obtained from the induced action by rescaling the central charge and fields by finite Z factors.

  9. Making Students Visible: Comparing Different Student Subgroup Sizes for Accountability. Update. Policy Memo 16-2B

    Science.gov (United States)

    Hough, Heather; Witte, Joe

    2016-01-01

    In May 2016, the authors released a policy memo comparing the effect of reporting subgroups at an n-size of 20+ compared to 100+. In response to this original memo, the U.S. Department of Education released a rule notice proposing changes to ESSA regulation §200.17 allowing states "to establish a range of n-sizes, not to exceed 30." To…

  10. Update on NHANES Dietary Data: Focus on Collection, Release, Analytical Considerations, and Uses to Inform Public Policy.

    Science.gov (United States)

    Ahluwalia, Namanjeet; Dwyer, Johanna; Terry, Ana; Moshfegh, Alanna; Johnson, Clifford

    2016-01-01

    NHANES is the cornerstone for national nutrition monitoring to inform nutrition and health policy. Nutritional assessment in NHANES is described with a focus on dietary data collection, analysis, and uses in nutrition monitoring. NHANES has been collecting thorough data on diet, nutritional status, and chronic disease in cross-sectional surveys with nationally representative samples since the early 1970s. Continuous data collection began in 1999 with public data release in 2-y cycles on ∼10,000 participants. In 2002, the Continuing Survey of Food Intakes by Individuals and the NHANES dietary component were merged, forming a consolidated dietary data collection known as What We Eat in America; since then, 24-h recalls have been collected on 2 d using the USDA's Automated Multiple-Pass Method. Detailed and targeted food-frequency questionnaires have been collected in some NHANES cycles. Dietary supplement use data have been collected (in detail since 2007) so that total nutrient intakes can be described for the population. The continuous NHANES can adapt its content to address emerging public health needs and reflect federal priorities. Changes in data collection methods are made after expert input and validation/crossover studies. NHANES dietary data are used to describe intake of foods, nutrients, food groups, and dietary patterns by the US population and large sociodemographic groups to plan and evaluate nutrition programs and policies. Usual dietary intake distributions can be estimated after adjusting for day-to-day variation. NHANES remains open and flexible to incorporate improvements while maintaining data quality and providing timely data to track the nation's nutrition and health status. In summary, NHANES collects dietary data in the context of its broad, multipurpose goals; the strengths and limitations of these data are also discussed in this review. © 2016 American Society for Nutrition.

  11. Update on NHANES Dietary Data: Focus on Collection, Release, Analytical Considerations, and Uses to Inform Public Policy12

    Science.gov (United States)

    Ahluwalia, Namanjeet; Dwyer, Johanna; Terry, Ana; Moshfegh, Alanna; Johnson, Clifford

    2016-01-01

    NHANES is the cornerstone for national nutrition monitoring to inform nutrition and health policy. Nutritional assessment in NHANES is described with a focus on dietary data collection, analysis, and uses in nutrition monitoring. NHANES has been collecting thorough data on diet, nutritional status, and chronic disease in cross-sectional surveys with nationally representative samples since the early 1970s. Continuous data collection began in 1999 with public data release in 2-y cycles on ∼10,000 participants. In 2002, the Continuing Survey of Food Intakes by Individuals and the NHANES dietary component were merged, forming a consolidated dietary data collection known as What We Eat in America; since then, 24-h recalls have been collected on 2 d using the USDA’s Automated Multiple-Pass Method. Detailed and targeted food-frequency questionnaires have been collected in some NHANES cycles. Dietary supplement use data have been collected (in detail since 2007) so that total nutrient intakes can be described for the population. The continuous NHANES can adapt its content to address emerging public health needs and reflect federal priorities. Changes in data collection methods are made after expert input and validation/crossover studies. NHANES dietary data are used to describe intake of foods, nutrients, food groups, and dietary patterns by the US population and large sociodemographic groups to plan and evaluate nutrition programs and policies. Usual dietary intake distributions can be estimated after adjusting for day-to-day variation. NHANES remains open and flexible to incorporate improvements while maintaining data quality and providing timely data to track the nation’s nutrition and health status. In summary, NHANES collects dietary data in the context of its broad, multipurpose goals; the strengths and limitations of these data are also discussed in this review. PMID:26773020

  12. Invasive potential of Borrelia burgdorferi sensu stricto ospC type L strains increases the possible disease risk to humans in the regions of their distribution

    Czech Academy of Sciences Publication Activity Database

    Golovchenko, Maryna; Šíma, Radek; Hajdušek, Ondřej; Grubhoffer, Libor; Oliver, J. H., Jr.; Rudenko, Natalia

    2014-01-01

    Roč. 7, NOV 28 2014 (2014), s. 538 ISSN 1756-3305 R&D Projects: GA ČR GP13-27630P; GA ČR GP13-12816P Institutional support: RVO:60077344 Keywords : B. burgdorferi ospC type * Invasive potential * Lyme disease * Southeastern U.S.A. * Tick vector * Vertebrate host Subject RIV: EC - Immunology Impact factor: 3.430, year: 2014

  13. Eleven-dimensional gauge theory for the M-algebra as an Abelian semigroup expansion of osp (32 vertical stroke 1)

    International Nuclear Information System (INIS)

    Izaurieta, F.; Rodriguez, E.; Salgado, P.

    2008-01-01

    A new Lagrangian realizing the symmetry of the M-algebra in eleven-dimensional space-time is presented. By means of the novel technique of Abelian semigroup expansion, a link between the M-algebra and the orthosymplectic algebra osp(32 vertical stroke 1) is established, and an M-algebra-invariant symmetric tensor of rank six is computed. This symmetric invariant tensor is a key ingredient in the construction of the new Lagrangian. The gauge-invariant Lagrangian is displayed in an explicitly Lorentz-invariant way by means of a subspace separation method based on the extended Cartan homotopy formula. (orig.)

  14. A guideline update for the practice of echocardiography in the cardiac screening of sports participants: a joint policy statement from the British Society of Echocardiography and Cardiac Risk in the Young

    Directory of Open Access Journals (Sweden)

    David Oxborough PhD

    2018-03-01

    Full Text Available Sudden cardiac death (SCD in an athlete is a rare but tragic event. In view of this, pre-participation cardiac screening is mandatory across many sporting disciplines to identify those athletes at risk. Echocardiography is a primary investigation utilized in the pre-participation setting and in 2013 the British Society of Echocardiography and Cardiac Risk in the Young produced a joint policy document providing guidance on the role of echocardiography in this setting. Recent developments in our understanding of the athlete’s heart and the application of echocardiography have prompted this 2018 update.

  15. Updating systematic reviews: an international survey.

    Directory of Open Access Journals (Sweden)

    Chantelle Garritty

    Full Text Available BACKGROUND: Systematic reviews (SRs should be up to date to maintain their importance in informing healthcare policy and practice. However, little guidance is available about when and how to update SRs. Moreover, the updating policies and practices of organizations that commission or produce SRs are unclear. METHODOLOGY/PRINCIPAL FINDINGS: The objective was to describe the updating practices and policies of agencies that sponsor or conduct SRs. An Internet-based survey was administered to a purposive non-random sample of 195 healthcare organizations within the international SR community. Survey results were analyzed using descriptive statistics. The completed response rate was 58% (n = 114 from across 26 countries with 70% (75/107 of participants identified as producers of SRs. Among responders, 79% (84/107 characterized the importance of updating as high or very-high and 57% (60/106 of organizations reported to have a formal policy for updating. However, only 29% (35/106 of organizations made reference to a written policy document. Several groups (62/105; 59% reported updating practices as irregular, and over half (53/103 of organizational respondents estimated that more than 50% of their respective SRs were likely out of date. Authors of the original SR (42/106; 40% were most often deemed responsible for ensuring SRs were current. Barriers to updating included resource constraints, reviewer motivation, lack of academic credit, and limited publishing formats. Most respondents (70/100; 70% indicated that they supported centralization of updating efforts across institutions or agencies. Furthermore, 84% (83/99 of respondents indicated they favoured the development of a central registry of SRs, analogous to efforts within the clinical trials community. CONCLUSIONS/SIGNIFICANCE: Most organizations that sponsor and/or carry out SRs consider updating important. Despite this recognition, updating practices are not regular, and many organizations lack

  16. Does providing more services increase the primary hospitals' revenue? An assessment of national essential medicine policy based on 2,675 counties in China.

    Directory of Open Access Journals (Sweden)

    Fei Chen

    Full Text Available To understand whether the increased outpatient service provision (OSP brings in enough additional income (excluding income from essential medicine for primary hospitals (INCOME to compensate for reduced costs of medicine.The two outcomes, annual OSP and INCOME for the period of 2008-2012, were collected from 34,506 primary hospitals in 2,675 counties in 31 provinces in China by the national surveillance system. The data had a four-level hierarchical structure; time points were nested within primary hospital, hospitals within county, and counties within province. We fitted bivariate five-level random effects regression models to examine correlations between OSP and INCOME in terms of their mean values and dose-response effects of the essential medicine policy (EMP. We adjusted for the effects of time period and selected hospital resources.The estimated correlation coefficients between the two outcomes' mean values were strongly positive among provinces (r = 0.910, moderately positive among counties (r = 0.380, and none among hospitals (r = 0.002 and time (r = 0.007. The correlation between their policy effects was weakly positive among provinces (r = 0.234, but none at the county and hospital levels. However, there were markedly negative correlation coefficients between the mean and policy effects at -0.328 for OSP and -0.541 for INCOME at the hospital level.There was no evidence to suggest an association between the two outcomes in terms of their mean values and dose-response effects of EMP at the hospital level. This indicated that increased OSP did not bring enough additional INCOME. Sustainable mechanisms to compensate primary hospitals are needed.

  17. Circular Updates

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Circular Updates are periodic sequentially numbered instructions to debriefing staff and observers informing them of changes or additions to scientific and specimen...

  18. Effect of policies on pellet production and forests in the U.S. South: a technical document supporting the Forest Service update of the 2010 RPA Assessment

    Science.gov (United States)

    Karen L. Abt; Robert C. Abt; Christopher S. Galik; Kenneth E. Skog

    2014-01-01

    Current policies in the European Union (EU) requiring renewable and low greenhouse gas-emitting energy are affecting wood products manufacturing and forests in the United States. These policies have led to increased U.S. pellet production and export to the EU, which has in turn affected U.S. forests and other wood products manufacturing. At this time, the primary...

  19. The type III effectors NleE and NleB from enteropathogenic E. coli and OspZ from Shigella block nuclear translocation of NF-kappaB p65.

    Directory of Open Access Journals (Sweden)

    Hayley J Newton

    2010-05-01

    Full Text Available Many bacterial pathogens utilize a type III secretion system to deliver multiple effector proteins into host cells. Here we found that the type III effectors, NleE from enteropathogenic E. coli (EPEC and OspZ from Shigella, blocked translocation of the p65 subunit of the transcription factor, NF-kappaB, to the host cell nucleus. NF-kappaB inhibition by NleE was associated with decreased IL-8 expression in EPEC-infected intestinal epithelial cells. Ectopically expressed NleE also blocked nuclear translocation of p65 and c-Rel, but not p50 or STAT1/2. NleE homologues from other attaching and effacing pathogens as well OspZ from Shigella flexneri 6 and Shigella boydii, also inhibited NF-kappaB activation and p65 nuclear import; however, a truncated form of OspZ from S. flexneri 2a that carries a 36 amino acid deletion at the C-terminus had no inhibitory activity. We determined that the C-termini of NleE and full length OspZ were functionally interchangeable and identified a six amino acid motif, IDSY(M/IK, that was important for both NleE- and OspZ-mediated inhibition of NF-kappaB activity. We also established that NleB, encoded directly upstream from NleE, suppressed NF-kappaB activation. Whereas NleE inhibited both TNFalpha and IL-1beta stimulated p65 nuclear translocation and IkappaB degradation, NleB inhibited the TNFalpha pathway only. Neither NleE nor NleB inhibited AP-1 activation, suggesting that the modulatory activity of the effectors was specific for NF-kappaB signaling. Overall our data show that EPEC and Shigella have evolved similar T3SS-dependent means to manipulate host inflammatory pathways by interfering with the activation of selected host transcriptional regulators.

  20. The type III effectors NleE and NleB from enteropathogenic E. coli and OspZ from Shigella block nuclear translocation of NF-kappaB p65.

    Science.gov (United States)

    Newton, Hayley J; Pearson, Jaclyn S; Badea, Luminita; Kelly, Michelle; Lucas, Mark; Holloway, Gavan; Wagstaff, Kylie M; Dunstone, Michelle A; Sloan, Joan; Whisstock, James C; Kaper, James B; Robins-Browne, Roy M; Jans, David A; Frankel, Gad; Phillips, Alan D; Coulson, Barbara S; Hartland, Elizabeth L

    2010-05-13

    Many bacterial pathogens utilize a type III secretion system to deliver multiple effector proteins into host cells. Here we found that the type III effectors, NleE from enteropathogenic E. coli (EPEC) and OspZ from Shigella, blocked translocation of the p65 subunit of the transcription factor, NF-kappaB, to the host cell nucleus. NF-kappaB inhibition by NleE was associated with decreased IL-8 expression in EPEC-infected intestinal epithelial cells. Ectopically expressed NleE also blocked nuclear translocation of p65 and c-Rel, but not p50 or STAT1/2. NleE homologues from other attaching and effacing pathogens as well OspZ from Shigella flexneri 6 and Shigella boydii, also inhibited NF-kappaB activation and p65 nuclear import; however, a truncated form of OspZ from S. flexneri 2a that carries a 36 amino acid deletion at the C-terminus had no inhibitory activity. We determined that the C-termini of NleE and full length OspZ were functionally interchangeable and identified a six amino acid motif, IDSY(M/I)K, that was important for both NleE- and OspZ-mediated inhibition of NF-kappaB activity. We also established that NleB, encoded directly upstream from NleE, suppressed NF-kappaB activation. Whereas NleE inhibited both TNFalpha and IL-1beta stimulated p65 nuclear translocation and IkappaB degradation, NleB inhibited the TNFalpha pathway only. Neither NleE nor NleB inhibited AP-1 activation, suggesting that the modulatory activity of the effectors was specific for NF-kappaB signaling. Overall our data show that EPEC and Shigella have evolved similar T3SS-dependent means to manipulate host inflammatory pathways by interfering with the activation of selected host transcriptional regulators.

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  9. Update History of This Database - Metabolonote | LSDB Archive [Life Science Database Archive metadata

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    Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...List Contact us Metabolonote Update History of This Database Date Update contents 2016/06/22 Metabolonote En... About This Database Database Description Download License Update History of This Database Site Policy | Contact Us Update History of This Database - Metabolonote | LSDB Archive ...

  10. Update History of This Database - Dicty_cDB | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...List Contact us Dicty_cDB Update History of This Database Date Update contents 2015/01/09 The original websi...ase Description Download License Update History of This Database Site Policy | Contact Us Update History of This Database - Dicty_cDB | LSDB Archive ...

  11. Update History of This Database - Q-TARO | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...List Contact us Q-TARO Update History of This Database Date Update contents 2014/10/20 The URL of the portal...ption Download License Update History of This Database Site Policy | Contact Us Update History of This Database - Q-TARO | LSDB Archive ...

  12. Update History of This Database - SAHG | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...List Contact us SAHG Update History of This Database Date Update contents 2016/05/09 SAHG English archive si...Download License Update History of This Database Site Policy | Contact Us Update History of This Database - SAHG | LSDB Archive ...

  13. Update History of This Database - ConfC | LSDB Archive [Life Science Database Archive metadata

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  14. Update History of This Database - DB-SPIRE | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...List Contact us DB-SPIRE Update History of This Database Date Update contents 2017/02/16 DB-SPIRE English ar...ase Description Download License Update History of This Database Site Policy | Contact Us Update History of This Database - DB-SPIRE | LSDB Archive ...

  15. Update History of This Database - JSNP | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...List Contact us JSNP Update History of This Database Date Update contents 2016/12/06 Description of the orig...ption Download License Update History of This Database Site Policy | Contact Us Update History of This Database - JSNP | LSDB Archive ...

  16. Update History of This Database - GenLibi | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

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  17. Update History of This Database - TogoTV | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...List Contact us TogoTV Update History of This Database Date Update contents 2017/05/12 TogoTV English archiv...ription Download License Update History of This Database Site Policy | Contact Us Update History of This Database - TogoTV | LSDB Archive ...

  18. Anti-O-specific polysaccharide (OSP) immune responses following vaccination with oral cholera vaccine CVD 103-HgR correlate with protection against cholera after infection with wild-type Vibrio cholerae O1 El Tor Inaba in North American volunteers.

    Science.gov (United States)

    Islam, Kamrul; Hossain, Motaher; Kelly, Meagan; Mayo Smith, Leslie M; Charles, Richelle C; Bhuiyan, Taufiqur Rahman; Kováč, Pavol; Xu, Peng; LaRocque, Regina C; Calderwood, Stephen B; Simon, Jakub K; Chen, Wilbur H; Haney, Douglas; Lock, Michael; Lyon, Caroline E; Kirkpatrick, Beth D; Cohen, Mitchell; Levine, Myron M; Gurwith, Marc; Harris, Jason B; Qadri, Firdausi; Ryan, Edward T

    2018-04-01

    Cholera is an acute voluminous dehydrating diarrheal disease caused by toxigenic strains of Vibrio cholerae O1 and occasionally O139. A growing body of evidence indicates that immune responses targeting the O-specific polysaccharide (OSP) of V. cholerae are involved in mediating protection against cholera. We therefore assessed whether antibody responses against OSP occur after vaccination with live attenuated oral cholera vaccine CVD 103-HgR, and whether such responses correlate with protection against cholera. We assessed adult North American volunteers (n = 46) who were vaccinated with 5 × 108 colony-forming units (CFU) of oral cholera vaccine CVD 103-HgR and then orally challenged with approximately 1 × 105 CFU of wild-type V. cholerae O1 El Tor Inaba strain N16961, either 10 or 90 days post-vaccination. Vaccination was associated with induction of significant serum IgM and IgA anti-OSP and vibriocidal antibody responses within 10 days of vaccination. There was significant correlation between anti-OSP and vibriocidal antibody responses. IgM and IgA anti-OSP responses on day 10 following vaccination were associated with lower post-challenge stool volume (r = -0.44, P = 0.002; r = -0.36, P = 0.01; respectively), and none of 27 vaccinees who developed a ≥1.5 fold increase in any antibody isotype targeting OSP on day 10 following vaccination compared to baseline developed moderate or severe cholera following experimental challenge, while 5 of 19 who did not develop such anti-OSP responses did (P = 0.01). Oral vaccination with live attenuated cholera vaccine CVD 103-HgR induces antibodies that target V. cholerae OSP, and these anti-OSP responses correlate with protection against diarrhea following experimental challenge with V. cholerae O1. ClinicalTrials.gov NCT01895855.

  19. Health economic assessment tools (HEAT) for walking and for cycling. Methodology and user guide.:Economic assessment of transport infrastructure and policies. 2014 Update

    OpenAIRE

    Kahlmeier, Sonja; Kelly, Paul; Foster, Charles; Gotschi, Thomas; Cavill, Nick; Dinsdale, Hywell; Woodcock, James; Schweizer, Christian; Rutter, Harry; Lieb, Christoph; Oja, Pekka; Racioppi, Francesca

    2014-01-01

    The promotion of cycling and walking for everyday physical activity not only promotes health but can also have positive effects on the environment.This booklet summarizes the tools and guidance developed to facilitate this shift: the methodology for the economic assessment of transport infrastructure and policies in relation to the health effects of walking and cycling; systematic reviews of the economic and health literature; and guidance on applying the health economic assessment tools and ...

  20. Multi-objective clustering technique based on k-nodes update policy and similarity matrix for mining communities in social networks

    Science.gov (United States)

    Shang, Ronghua; Liu, Huan; Jiao, Licheng

    2017-11-01

    This paper proposes a relatively all-purpose network clustering technique based on the framework of multi-objective evolutionary algorithms, which can effectively dispose the issue of community detection in unsigned social networks, as well as in signed social networks. Firstly, we formulate a generalized similarity function to construct a similarity matrix, and then a pre-partitioning strategy is projected according to the similarity matrix. The pre-partitioning strategy merely considers nodes with high similarity values, which avoids the interference of noise nodes during the label update phase. In this way, at the initial phase of the algorithm, nodes with strong connections are fleetly gathered into sub-communities. Secondly, we elaborately devise a crossover operator, called cross-merging operator, to merge sub-communities generated by the pre-partitioning technique. Moreover, a special mutation operator, based on the similarity matrix of nodes, is implemented to adjust boundary nodes connecting different communities. Finally, to handle different types of networks, we, therefore, have presented the novel multi-objective optimization models for this issue. Through a bulk of rigorous experiments on both unsigned and signed social networks, the preeminent clustering performance illustrate that the proposed algorithm is capable of mining communities effectively.

  1. Recommendations for reporting of secondary findings in clinical exome and genome sequencing, 2016 update (ACMG SF v2.0): a policy statement of the American College of Medical Genetics and Genomics.

    Science.gov (United States)

    Kalia, Sarah S; Adelman, Kathy; Bale, Sherri J; Chung, Wendy K; Eng, Christine; Evans, James P; Herman, Gail E; Hufnagel, Sophia B; Klein, Teri E; Korf, Bruce R; McKelvey, Kent D; Ormond, Kelly E; Richards, C Sue; Vlangos, Christopher N; Watson, Michael; Martin, Christa L; Miller, David T

    2017-02-01

    the process was implemented. Applying the new process while upholding the core principles of the original policy statement resulted in the addition of four genes and removal of one gene; one gene did not meet criteria for inclusion. The updated secondary findings minimum list includes 59 medically actionable genes recommended for return in clinical genomic sequencing. We discuss future areas of focus, encourage continued input from the medical community, and call for research on the impact of returning genomic secondary findings.Genet Med 19 2, 249-255.

  2. Identification and functional characterisation of Complement Regulator Acquiring Surface Protein-1 of serum resistant Borrelia garinii OspA serotype 4

    Directory of Open Access Journals (Sweden)

    Zipfel Peter F

    2010-02-01

    Full Text Available Abstract Background B. burgdorferi sensu lato (sl is the etiological agent of Lyme borreliosis in humans. Spirochetes have adapted themselves to the human immune system in many distinct ways. One important immune escape mechanism for evading complement activation is the binding of complement regulators Factor H (CFH or Factor H-like protein1 (FHL-1 to Complement Regulator-Acquiring Surface Proteins (CRASPs. Results We demonstrate that B. garinii OspA serotype 4 (ST4 PBi resist complement-mediated killing by binding of FHL-1. To identify the primary ligands of FHL-1 four CspA orthologs from B. garinii ST4 PBi were cloned and tested for binding to human CFH and FHL-1. Orthologs BGA66 and BGA71 were found to be able to bind both complement regulators but with different intensities. In addition, all CspA orthologs were tested for binding to mammalian and avian CFH. Distinct orthologs were able to bind to CFH of different animal origins. Conclusions B. garinii ST4 PBi is able to evade complement killing and it can bind FHL-1 to membrane expressed proteins. Recombinant proteins BGA66 can bind FHL-1 and human CFH, while BGA71 can bind only FHL-1. All recombinant CspA orthologs from B. garinii ST4 PBi can bind CFH from different animal origins. This partly explains the wide variety of animals that can be infected by B. garinii.

  3. Measuring the burden of disease and injury in Spain using disability-adjusted life years: an updated and policy-oriented overview.

    Science.gov (United States)

    Gènova-Maleras, R; Álvarez-Martín, E; Morant-Ginestar, C; Fernández de Larrea-Baz, N; Catalá-López, F

    2012-12-01

    To provide a comprehensive and detailed overview of the burden of disease in Spain for 2008. Implications for public health policies are discussed. Cross-sectional population-based study. Disability-adjusted life years (DALYs) were calculated at country level using the methodology developed in the Global Burden of Disease study. DALYs were divided into years of life lost and years of life lived with disability. Results were obtained using Spanish mortality data for 2008 and morbidity data estimated previously by the World Health Organization for Euro-A. In 2008, DALYs lost due to all diseases and injuries were estimated at 5.1 million. Non-communicable diseases accounted for 89.2% of the total DALYs. The leading causes of DALYs were neurological and mental disorders (29.9%), malignant neoplasms (15.8%) and cardiovascular diseases (12.5%). The main specific causes included depression (5.5%), ischaemic heart disease (5.5%), lung cancer (5.3%) and alcohol abuse (4.7%) among males; and depression (11.7%), dementias (10.0%), hearing loss (4.2%) and cerebrovascular disease (3.5%) among females. Measuring DALYs specifically for Spain represents a systematic analysis of population health losses, and also provides an important measure to track the outcomes of future health interventions. Copyright © 2012 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

  4. Biomass [updated

    Energy Technology Data Exchange (ETDEWEB)

    Turhollow Jr, Anthony F [ORNL

    2016-01-01

    Biomass resources and conversion technologies are diverse. Substantial biomass resources exist including woody crops, herbaceous perennials and annuals, forest resources, agricultural residues, and algae. Conversion processes available include fermentation, gasification, pyrolysis, anaerobic digestion, combustion, and transesterification. Bioderived products include liquid fuels (e.g. ethanol, biodiesel, and gasoline and diesel substitutes), gases, electricity, biochemical, and wood pellets. At present the major sources of biomass-derived liquid fuels are from first generation biofuels; ethanol from maize and sugar cane (89 billion L in 2013) and biodiesel from vegetable oils and fats (24 billion liters in 2011). For other than traditional uses, policy in the forms of mandates, targets, subsidies, and greenhouse gas emission targets has largely been driving biomass utilization. Second generation biofuels have been slow to take off.

  5. Update History of This Database - RGP estmap2001 | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...List Contact us RGP estmap2001 Update History of This Database Date Update contents 2015/04/02 RGP estmap200...stmap2001/index.html) is opened. About This Database Database Description Download License Update History... of This Database Site Policy | Contact Us Update History of This Database - RGP estmap2001 | LSDB Archive ...

  6. Update History of This Database - DMPD | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...List Contact us DMPD Update History of This Database Date Update contents 2010/03/29 DMPD English archive si....jp/macrophage/ ) is released. About This Database Database Description Download License Update History of T...his Database Site Policy | Contact Us Update History of This Database - DMPD | LSDB Archive ...

  7. Update History of This Database - DGBY | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...List Contact us DGBY Update History of This Database Date Update contents 2014/10/20 The URL of the portal s...aro.affrc.go.jp/yakudachi/yeast/index.html ) is opened. About This Database Database Description Download License Update History... of This Database Site Policy | Contact Us Update History of This Database - DGBY | LSDB Archive ...

  8. Update History of This Database - RGP gmap2000 | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...List Contact us RGP gmap2000 Update History of This Database Date Update contents 2015/03/10 RGP gmap2000 En...icmap2000/index.html) is opened. About This Database Database Description Download License Update History... of This Database Site Policy | Contact Us Update History of This Database - RGP gmap2000 | LSDB Archive ...

  9. Update History of This Database - NBDC NikkajiRDF | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...List Contact us NBDC NikkajiRDF Update History of This Database Date Update contents 2017/02/17 Archive vers...iweb.jst.go.jp/ ) is opened. About This Database Database Description Download License Update History... of This Database Site Policy | Contact Us Update History of This Database - NBDC NikkajiRDF | LSDB Archive ...

  10. Update History of This Database - RMOS | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...List Contact us RMOS Update History of This Database Date Update contents 2015/10/27 RMOS English archive si...12 RMOS (http://cdna01.dna.affrc.go.jp/RMOS/) is opened. About This Database Database Description Download License Update History... of This Database Site Policy | Contact Us Update History of This Database - RMOS | LSDB Archive ...

  11. Policies and procedures for considering environmental impacts

    Science.gov (United States)

    2006-03-20

    This order updates the FAA agency-wide policies and procedures for compliance with the : National Environmental Policy Act (NEPA) and implementing regulations issued by the Council : on Environmental Quality (40 CFR parts 1500-1508). The provisions o...

  12. Enhancement of immune response towards non-lipidized Borrelia burgdorferi recombinant OspC antigen by binding onto the surface of metallochelating nanoliposomes with entrapped lipophilic derivatives of norAbuMDP

    Czech Academy of Sciences Publication Activity Database

    Křupka, M.; Mašek, J.; Bartheldyová, E.; Turánek Knotigová, P.; Plocková, J.; Korvasová, Z.; Škrabalová, M.; Koudelka, Š.; Kulich, P.; Zachová, K.; Czerneková, L.; Strouhal, O.; Horynová, M.; Šebela, M.; Miller, A. D.; Ledvina, Miroslav; Raška, M.; Turánek, J.

    2012-01-01

    Roč. 160, č. 2 (2012), s. 374-381 ISSN 0168-3659 R&D Projects: GA ČR(CZ) GAP304/10/1951; GA TA ČR TA01011165; GA AV ČR(CZ) KAN200520703; GA AV ČR KAN200100801 Grant - others:GA UP(CZ) LF-2010-014; GA UP(CZ) LF-2011-002 Institutional research plan: CEZ:AV0Z40550506 Keywords : Borrelia burgdorferi * OspC * metallochelating liposomes * MDP Subject RIV: CC - Organic Chemistry Impact factor: 7.633, year: 2012

  13. DoD Green Remediation Policy Update

    Science.gov (United States)

    2011-05-11

    decisions and practices  Green remediation is the practice of considering all environmental effects of remedy implementation and incorporating... reforestation irrigation – More than 30,000 tons of soil remediated and 270 tons of lead bullet fragments were reclaimed for recycling  Footprint Reduction

  14. Geothermal Brief: Market and Policy Impacts Update

    Energy Technology Data Exchange (ETDEWEB)

    Speer, B.

    2012-10-01

    Utility-scale geothermal electricity generation plants have generally taken advantage of various government initiatives designed to stimulate private investment. This report investigates these initiatives to evaluate their impact on the associated cost of energy and the development of geothermal electric generating capacity using conventional hydrothermal technologies. We use the Cost of Renewable Energy Spreadsheet Tool (CREST) to analyze the effects of tax incentives on project economics. Incentives include the production tax credit, U.S. Department of Treasury cash grant, the investment tax credit, and accelerated depreciation schedules. The second half of the report discusses the impact of the U.S. Department of Energy's (DOE) Loan Guarantee Program on geothermal electric project deployment and possible reasons for a lack of guarantees for geothermal projects. For comparison, we examine the effectiveness of the 1970s DOE drilling support programs, including the original loan guarantee and industry-coupled cost share programs.

  15. 25 energy efficiency policy recommendations. 2011 update

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    The IEA recommends that G8 leaders adopt and urgently implement this package of measures to significantly enhance energy efficiency. This package was developed under the Gleneagles G8 Plan of Action, which mandates the pursuit of a clean, clever and competitive energy future.

  16. Internet Journal of Medical Update - EJOURNAL

    African Journals Online (AJOL)

    Internet Journal of Medical Update (IJMU) is an international e-journal which provides a multidisciplinary forum for the exchange of current ideas in form of review articles, original research work, interesting case reports, etc. among medical professionals. Editorial policy: The Editor receives manuscripts with the ...

  17. OSP-Immunofluorescent remyelinating oligodendrocytes in the brainstem of toxically-demyelinated Wistar rats Oligodendrócitos remielinizantes positivos para OSP - proteína específica do oligodendrócito- no tronco encefálico de ratos Wistar desmielinizados toxicamente

    Directory of Open Access Journals (Sweden)

    Eliza Simone Viégas Sallis

    2006-06-01

    Full Text Available Central nervous system (CNS remyelination following toxically-induced demyelination is a well known process. Oligodendrocytes constitute the bulk of the myelinating cells in the brain whereas Schwann cells overwhelm oligodendrocytes numbers in spinal cord remyelination. Despite the common knowledge of these facts, we still do not know completely the origin of both remyelinating cells. The present study investigated the participation of mature oligodendrocytes in remyelination after ethidium-bromide (EB induced demyelination in the brainstem of normal and cyclosporin A-immunosuppressed Wistar rats. Thirty adult female rats were divided into three experimental groups. In group 1 the rats received a single intracisternal injection of 10 muL of 0.1% ethidium bromide (EB in 0.9% saline (n=10; in group 2 the rats received the EB injection while immunosuppressed with cyclosporin A (n=10; in group 3 the rats received a single 10 muL injection of 0.9% saline while treated with cyclosporin A. The rats were killed at 15, 21 and 31 days after injection. Within the EB lesions, from 15 days onward many cells within the periphery of the lesions stained positive for OSP (oligodendrocyte specific protein a marker for mature oligodendrocytes and myelin. This cell marking signals that, at least, part of the process of repairing the myelin sheaths is carried out by mature cells of the oligodendrocyte lineage.A remielinização do sistema nervoso central após desmielinização tóxica é um processo bem conhecido. No encéfalo, os oligodendrócitos remielinizam uma área maior do que na medula espinhal, onde as células de Schwann são preponderantes. Embora esses fatos sejam bem conhecidos, ainda não se conhece com certeza a origem das células remielinizantes. Esta investigação foi desenhada para esclarecer a participação de oligodendrócitos maduros na reconstrução das bainhas perdidas após a desmielinização induzida por brometo de etídio (BE no

  18. 78 FR 68849 - Draft Current Intelligence Bulletin “Update of NIOSH Carcinogen Classification and Target Risk...

    Science.gov (United States)

    2013-11-15

    ..., benzene, and others. Further, the existing NIOSH carcinogen policy does not allow for classification on...; Docket Number NIOSH 240-A] Draft Current Intelligence Bulletin ``Update of NIOSH Carcinogen... document for public comment entitled ``Current Intelligence Bulletin: Update of NIOSH Carcinogen...

  19. Update History of This Database - Togo Picture Gallery | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available List Contact us Togo Picture Gallery Update History of This Database Date Update contents 2017/05/16 Togo Picture Gallery... English archive site is opened. 2011/04/01 Togo Picture Gallery ( http://togotv.dbcls.jp/ja/pi...se Site Policy | Contact Us Update History of This Database - Togo Picture Gallery | LSDB Archive ...

  20. Update History of This Database - Arabidopsis Phenome Database | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available List Contact us Arabidopsis Phenome Database Update History of This Database Date Update contents 2017/02/27... Arabidopsis Phenome Database English archive site is opened. - Arabidopsis Phenome Database (http://jphenom...e.info/?page_id=95) is opened. About This Database Database Description Download License Update History of This Database... Site Policy | Contact Us Update History of This Database - Arabidopsis Phenome Database | LSDB Archive ...

  1. Update History of This Database - SKIP Stemcell Database | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available List Contact us SKIP Stemcell Database Update History of This Database Date Update contents 2017/03/13 SKIP Stemcell Database... English archive site is opened. 2013/03/29 SKIP Stemcell Database ( https://www.skip.med.k...eio.ac.jp/SKIPSearch/top?lang=en ) is opened. About This Database Database Description Download License Upda...te History of This Database Site Policy | Contact Us Update History of This Database - SKIP Stemcell Database | LSDB Archive ...

  2. Investing in updating: how do conclusions change when Cochrane systematic reviews are updated?

    Directory of Open Access Journals (Sweden)

    McKenzie Joanne E

    2005-10-01

    Full Text Available Abstract Background Cochrane systematic reviews aim to provide readers with the most up-to-date evidence on the effects of healthcare interventions. The policy of updating Cochrane reviews every two years consumes valuable time and resources and may not be appropriate for all reviews. The objective of this study was to examine the effect of updating Cochrane systematic reviews over a four year period. Methods This descriptive study examined all completed systematic reviews in the Cochrane Database of Systematic Reviews (CDSR Issue 2, 1998. The latest version of each of these reviews was then identified in CDSR Issue 2, 2002 and changes in the review were described. For reviews that were updated within this time period and had additional studies, we determined whether their conclusion had changed and if there were factors that were predictive of this change. Results A total of 377 complete reviews were published in CDSR Issue 2, 1998. In Issue 2, 2002, 14 of these reviews were withdrawn and one was split, leaving 362 reviews to examine for the purpose of this study. Of these reviews, 254 (70% were updated. Of these updated reviews, 23 (9% had a change in conclusion. Both an increase in precision and a change in statistical significance of the primary outcome were predictive of a change in conclusion of the review. Conclusion The concerns around a lack of updating for some reviews may not be justified considering the small proportion of updated reviews that resulted in a changed conclusion. A priority-setting approach to the updating of Cochrane systematic reviews may be more appropriate than a time-based approach. Updating all reviews as frequently as every two years may not be necessary, however some reviews may need to be updated more often than every two years.

  3. Investing in updating: how do conclusions change when Cochrane systematic reviews are updated?

    Science.gov (United States)

    French, Simon D; McDonald, Steve; McKenzie, Joanne E; Green, Sally E

    2005-10-14

    Cochrane systematic reviews aim to provide readers with the most up-to-date evidence on the effects of healthcare interventions. The policy of updating Cochrane reviews every two years consumes valuable time and resources and may not be appropriate for all reviews. The objective of this study was to examine the effect of updating Cochrane systematic reviews over a four year period. This descriptive study examined all completed systematic reviews in the Cochrane Database of Systematic Reviews (CDSR) Issue 2, 1998. The latest version of each of these reviews was then identified in CDSR Issue 2, 2002 and changes in the review were described. For reviews that were updated within this time period and had additional studies, we determined whether their conclusion had changed and if there were factors that were predictive of this change. A total of 377 complete reviews were published in CDSR Issue 2, 1998. In Issue 2, 2002, 14 of these reviews were withdrawn and one was split, leaving 362 reviews to examine for the purpose of this study. Of these reviews, 254 (70%) were updated. Of these updated reviews, 23 (9%) had a change in conclusion. Both an increase in precision and a change in statistical significance of the primary outcome were predictive of a change in conclusion of the review. The concerns around a lack of updating for some reviews may not be justified considering the small proportion of updated reviews that resulted in a changed conclusion. A priority-setting approach to the updating of Cochrane systematic reviews may be more appropriate than a time-based approach. Updating all reviews as frequently as every two years may not be necessary, however some reviews may need to be updated more often than every two years.

  4. An Update on Memory Reconsolidation Updating.

    Science.gov (United States)

    Lee, Jonathan L C; Nader, Karim; Schiller, Daniela

    2017-07-01

    The reactivation of a stored memory in the brain can make the memory transiently labile. During the time it takes for the memory to restabilize (reconsolidate) the memory can either be reduced by an amnesic agent or enhanced by memory enhancers. The change in memory expression is related to changes in the brain correlates of long-term memory. Many have suggested that such retrieval-induced plasticity is ideally placed to enable memories to be updated with new information. This hypothesis has been tested experimentally, with a translational perspective, by attempts to update maladaptive memories to reduce their problematic impact. We review here progress on reconsolidation updating studies, highlighting their translational exploitation and addressing recent challenges to the reconsolidation field. Copyright © 2017 Elsevier Ltd. All rights reserved.

  5. Morocco; Financial System Stability Assessment: Update

    OpenAIRE

    International Monetary Fund

    2008-01-01

    This paper presents an update to the Financial System Stability Assessment on Morocco. Major reforms have been achieved since the 2002 Financial Sector Assessment Program (FSAP) within a policy of actively promoting economic and financial sector opening. The 2002 FSAP recommendations have been largely implemented. Although the financial system is stable and considerably more robust than in the past, the liberalization of capital flows and increased exchange rate flexibility present challenges...

  6. Update on women in physics in Argentina

    Science.gov (United States)

    Brudny, Vera; Lagorio, Cecilia; Frechero, Marisa; Tamarit, Francisco

    2013-03-01

    Data collected 10 years ago in Argentina concluded that women in physics were underrepresented in many instances and that a "crystal ceiling" was firmly in place. We have collected updated data for several indicators and compared them with those obtained 10 years ago. Although there is not a clear conclusion to be drawn from this comparison, we try to explain the results within the framework of the changes in scientific policies in Argentina.

  7. Update on women in physics in Argentina

    OpenAIRE

    Brudny, Vera Leonor; Lagorio, Cecilia; Frechero, Marisa Alejandra; Tamarit, Francisco

    2016-01-01

    Data collected 10 years ago in Argentina concluded that women in physics were underrepresented in many instances and that a “crystal ceiling” was firmly in place. We have collected updated data for several indicators and compared them with those obtained 10 years ago. Although there is not a clear conclusion to be drawn from this comparison, we try to explain the results within the framework of the changes in scientific policies in Argentina. Fil: Brudny, Vera Leonor. Universidad de Buenos...

  8. Red Hill Updates

    Science.gov (United States)

    This and other periodic updates are intended to keep the public informed on major progress being made to protect public health and the environment at the Red Hill Underground Fuel Storage Facility in Hawaii.

  9. Update History of This Database - PGDBj - Ortholog DB | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available List Contact us PGDBj - Ortholog DB Update History of This Database Date Update contents 2017/03/07 PGDBj Orth...L of the Whole data download The URL of The original website information 2014/05/12 PGDBj Ortholog DB (Relea...se57 ver.) English archive site is opened. (Archive V1) 2012/08/01 PGDBj Ortholog DB ( http://pgdbj.jp/ortho...e Update History of This Database Site Policy | Contact Us Update History of This Database - PGDBj - Ortholog DB | LSDB Archive ... ...switchLanguage; BLAST Search Image Search Home About Archive Update History Data

  10. Update History of This Database - RGP physicalmap | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available calmap Update History of This Database Date Update contents 2015/07/07 RGP physical...map English archive site is opened. 2013/04/01 The URL of RGP physicalmap is changed to ... http://rgp.dna.affrc.go.jp/E/publicdata/phys...icalmap/physicalmap.html . 1997/07/09 RGP physicalmap (http://rgp.dna.affrc.go.jp/publicdata/physicalmap/phy...escription Download License Update History of This Database Site Policy | Contact Us Update History of This Database - RGP physicalmap | LSDB Archive ... ...switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us RGP physi

  11. Update History of This Database - Gene Name Thesaurus | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available List Contact us Gene Name Thesaurus Update History of This Database Date Update contents 2013/01/17 Added a simple search URL for the... ... Gene Name Thesaurus ... data. 2012/01/17 License is updated. 2010/03/29 Gene Name The...saurus English archive site is opened. 2007/3 Gene Name Thesaurus is released in MEXT Integrated Database P...tabase Database Description Download License Update History of This Database Site Policy | Contact Us Update History of This Database - Gene Name Thesaurus | LSDB Archive ...

  12. Establishment of a minor groove binder-probe based quantitative real time PCR to detect Borrelia burgdorferi sensu lato and differentiation of Borrelia spielmanii by ospA-specific conventional PCR

    Directory of Open Access Journals (Sweden)

    Strube Christina

    2010-08-01

    Full Text Available Abstract Background Borrelia burgdorferi sensu lato (sl, the causative agent of Lyme borreliosis, is transmitted by ticks of the genus Ixodes as vector. For identification of Borrelia infections in ticks a TaqMan™ minor groove binder (MGB probe-based quantitative real time PCR (qPCR was established targeting the 5S-23S intergenic spacer. Extension to a duplex qPCR included an Ixodes spp. positive control to verify successful DNA isolation. Besides qPCR, an ospA-specific conventional PCR for species-specific identification of B. spielmanii was established. Afterwards 1000 I. ricinus flagged in the city of Hanover, Germany, were investigated for B. burgdorferi sl infections followed by species identification. Furthermore, I. hexagonus ticks were investigated to proof applicability of the PCRs. Results Quantitative real time PCR (qPCR identifying B. burgdorferi sl in ticks was able to detect 1-10 copies per reaction. B. spielmanii ospA-specific conventional PCR was also highly specific and showed no cross reactions with the other tested Borrelia species. From 1000 hanoveranian ticks 24.3% were positive compared to only 7.4% positives by dark-field microscopy. Related to tick stage 1.7% larvae, 18.1% nymphs, and 34.6% adults were positive. The most frequent species was B. garinii, followed by B. afzelii, B. spielmanii, B. valaisiana and B. burgdorferi sensu stricto (ss. 70.6% of I. ricinus were mono-infected, whereas 28.0% and 1.4% were infected with two and three Borrelia species, respectively. From 232 I. hexagonus collected from hedgehogs in different sites of Germany, qPCR detected 5.7% to be infected with B. burgdorferi sl, which were identified as B. afzelii, B. garinii and B. spielmanii. Conclusions The evaluated qPCR to detect B. burgdorferi sl in Ixodes spp. is highly specific and sensitive. As a duplex qPCR including detection of Ixodes spp. DNA it is the first DNA based technique incorporating a control for successful DNA isolation from

  13. 2007 State Policies on Assessment Participation and Accommodations for Students with Disabilities. Synthesis Report 69

    Science.gov (United States)

    Christensen, Laurene L.; Lazarus, Sheryl S.; Crone, Melissa; Thurlow, Martha L.

    2008-01-01

    This document presents an update of a 2006 report from NCEO tracking and analyzing state policies on assessment participation and accommodations since 1992. The purpose of the current analysis is to update information on these policies that was last reported by NCEO in 2006 (based on 2005 data). In this analysis, policies from all 50 states, plus…

  14. Update of European bioethics

    DEFF Research Database (Denmark)

    Rendtorff, Jacob Dahl

    2015-01-01

    This paper presents an update of the research on European bioethics undertaken by the author together with Professor Peter Kemp since the 1990s, on Basic ethical principles in European bioethics and biolaw. In this European approach to basic ethical principles in bioethics and biolaw......, the principles of autonomy, dignity, integrity and vulnerability are proposed as the most important ethical principles for respect for the human person in biomedical and biotechnological development. This approach to bioethics and biolaw is presented here in a short updated version that integrates the earlier...... research in a presentation of the present understanding of the basic ethical principles in bioethics and biolaw....

  15. Updating action domain descriptions.

    Science.gov (United States)

    Eiter, Thomas; Erdem, Esra; Fink, Michael; Senko, Ján

    2010-10-01

    Incorporating new information into a knowledge base is an important problem which has been widely investigated. In this paper, we study this problem in a formal framework for reasoning about actions and change. In this framework, action domains are described in an action language whose semantics is based on the notion of causality. Unlike the formalisms considered in the related work, this language allows straightforward representation of non-deterministic effects and indirect effects of (possibly concurrent) actions, as well as state constraints; therefore, the updates can be more general than elementary statements. The expressivity of this formalism allows us to study the update of an action domain description with a more general approach compared to related work. First of all, we consider the update of an action description with respect to further criteria, for instance, by ensuring that the updated description entails some observations, assertions, or general domain properties that constitute further constraints that are not expressible in an action description in general. Moreover, our framework allows us to discriminate amongst alternative updates of action domain descriptions and to single out a most preferable one, based on a given preference relation possibly dependent on the specified criteria. We study semantic and computational aspects of the update problem, and establish basic properties of updates as well as a decomposition theorem that gives rise to a divide and conquer approach to updating action descriptions under certain conditions. Furthermore, we study the computational complexity of decision problems around computing solutions, both for the generic setting and for two particular preference relations, viz. set-inclusion and weight-based preference. While deciding the existence of solutions and recognizing solutions are PSPACE-complete problems in general, the problems fall back into the polynomial hierarchy under restrictions on the additional

  16. BI-RADS update.

    Science.gov (United States)

    Mercado, Cecilia L

    2014-05-01

    The updated American College of Radiology (ACR) Breast Imaging Reporting and Data System (BI-RADS) has been newly released. This article summarizes the changes and updates that have been made to BI-RADS. The goal of the revised edition continues to be the same: to improve clarification in image interpretation, maintain reporting standardization, and simplify the monitoring of outcomes. The new BI-RADS also introduces new terminology to provide a more universal lexicon across all 3 imaging modalities. Copyright © 2014 Elsevier Inc. All rights reserved.

  17. Adição da proteína específica do oviduto de porcas (pOSP e da melatonina em meios de maturação e o efeito na clivagem in vitro de embriões suínos

    Directory of Open Access Journals (Sweden)

    T.S. Kawamoto

    Full Text Available RESUMO No presente estudo, utilizou-se a melatonina e a proteína específica do oviduto (pOSP nos meios de maturação in vitro. Foram avaliadas a expansão do complexo cumulus-ovócito (CCOs, as concentrações intracelulares de espécies reativas de oxigênio (ROS e o desenvolvimento embrionário nos diferentes grupos (C = controle; T1 = somente com melatonina; T2 = com melatonina e pOSP e T3 somente com pOSP. No tocante à expansão do CCOs, houve diferença (P0,05. Na dosagem de ROS, não houve diferença entre os valores médios obtidos no grupo C (26,4±10,9 e o valor verificado no grupo T1 (23,4±7,8, porém no grupo T2 (21,3±9,7 o valor médio mostrou-se satisfatório em relação ao valor do grupo C. No entanto, o valor médio do grupo T3 (16,6±10,5 foi o que demonstrou resultado mais satisfatório quando comparado aos demais grupos (P0,05 entre os valores obtidos entre o grupo C (48,9 % e os valores verificados nos grupos T1 (51,5 %, T2 (50 %, T3 (57,7 %, nem destes entre si. Este estudo permitiu concluir que a proteína específica do oviduto recombinante e a melatonina foram eficientes em melhorar a expansão dos CCOs. Além disso, as células tratadas com pOSP mostraram-se com menor quantidade de ROS, podendo a pOSP ser considerada um antioxidante proteico.

  18. USAID Policy: Gender equality and female empowerment policy

    OpenAIRE

    United States Agency for International Development (USAID)

    2012-01-01

    Metadata only record This report is an update on USAID's progress towards gender equity and female empowerment since 1982. This policy strives towards positive development that is beneficial to men, women, and children. The goals are to reduce gender disparity in access to resources, reduce gender-based violence, and increase women's agency, leadership, and decision-making.

  19. Supreme Court Update

    Science.gov (United States)

    Taylor, Kelley R.

    2009-01-01

    "Chief Justice Flubs Oath." "Justice Ginsburg Has Cancer Surgery." At the start of this year, those were the news headlines about the U.S. Supreme Court. But January 2009 also brought news about key education cases--one resolved and two others on the docket--of which school administrators should take particular note. The Supreme Court updates on…

  20. Update: Biological Nitrogen Fixation.

    Science.gov (United States)

    Wiseman, Alan; And Others

    1985-01-01

    Updates knowledge on nitrogen fixation, indicating that investigation of free-living nitrogen-fixing organisms is proving useful in understanding bacterial partners and is expected to lead to development of more effective symbioses. Specific areas considered include biochemistry/genetics, synthesis control, proteins and enzymes, symbiotic systems,…

  1. Liver transplantation : an update

    NARCIS (Netherlands)

    Verdonk, R. C.; Van den Berg, A. P.; Slooff, M. J. H.; Porte, R. J.; Haagsma, E. B.

    2007-01-01

    Liver transplantation has been an accepted treatment for end-stage liver disease since the 1980s. Currently it is a highly successful treatment for this indication. The aim of this review is to give a general update on recent developments in the field of liver transplantation. In the last decades

  2. Phaeochromocytoma – an update

    African Journals Online (AJOL)

    but has been advocated as the test of choice in many studies. The management of a phaeochromocytoma is mainly surgical and requires careful patient preparation to avoid catecholamine-induced complications during surgery. This review provides an update on phaeochromocytomas. Genetics. 68. J e. MDS a. November ...

  3. Updating protocols prodigy.

    Science.gov (United States)

    Ambrose, Kate

    2005-04-01

    If you are updating protocols, why not try the Prodigy website, at www.prodigy.nhs.uk ? It is a source of clinical knowledge on a range oftopics that is based on best evidence and organised to support clinical decision making.

  4. Update of telephone exchange

    CERN Multimedia

    2006-01-01

    As part of the upgrade of telephone services, the CERN switching centre will be updated on Monday 3 July between 8.00 p.m. and 3.00 a.m. Telephone services may be disrupted and possibly even interrupted during this operation.We apologise in advance for any inconvenience this may cause. CERN TELECOM Service

  5. Update of telephone exchange

    CERN Multimedia

    2006-01-01

    As part of the upgrade of telephone services, the CERN switching centre will be updated on between Monday 23 October 8.00 p.m. and Tuesday 24 October 2.00 a.m. Telephone services may be disrupted and possibly even interrupted during this operation. We apologise in advance for any inconvenience this may cause. CERN TELECOM Service

  6. Update of telephone exchange

    CERN Multimedia

    2006-01-01

    As part of the upgrade of telephone services, the CERN switching centre will be updated on Monday 3 July between 8.00 p.m. and 3.00 a.m. Telephone services may be disrupted and possibly even interrupted during this operation. We apologise in advance for any inconvenience this may cause. CERN TELECOM Service

  7. Update of telephone exchange

    CERN Multimedia

    2006-01-01

    As part of the upgrade of telephone services, the CERN switching centre will be updated on Wednesday 14 June between 8.00 p.m. and midnight. Telephone services may be disrupted and possibly even interrupted during this operation. We apologise in advance for any inconvenience this may cause. CERN TELECOM Service

  8. 78 FR 34383 - Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation...

    Science.gov (United States)

    2013-06-07

    ... purposes of the statement of policy published in the July 2, 1992 issue of the Federal Register (57 FR... FEDERAL DEPOSIT INSURANCE CORPORATION Update to Notice of Financial Institutions for Which the...: Federal Deposit Insurance Corporation. ACTION: Update listing of financial institutions in liquidation...

  9. 76 FR 2687 - Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation...

    Science.gov (United States)

    2011-01-14

    ... purposes of the statement of policy published in the July 2, 1992 issue of the Federal Register (57 FR... FEDERAL DEPOSIT INSURANCE CORPORATION Update to Notice of Financial Institutions for Which the...: Federal Deposit Insurance Corporation. ACTION: Update Listing of Financial Institutions in Liquidation...

  10. 78 FR 35929 - Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation...

    Science.gov (United States)

    2013-06-14

    ... purposes of the statement of policy published in the July 2, 1992 issue of the Federal Register (57 FR... FEDERAL DEPOSIT INSURANCE CORPORATION Update to Notice of Financial Institutions for Which the...: Federal Deposit Insurance Corporation. ACTION: Update Listing of Financial Institutions in Liquidation...

  11. 77 FR 31357 - Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation...

    Science.gov (United States)

    2012-05-25

    ... purposes of the statement of policy published in the July 2, 1992 issue of the Federal Register (57 FR... FEDERAL DEPOSIT INSURANCE CORPORATION Update to Notice of Financial Institutions for Which the...: Federal Deposit Insurance Corporation. ACTION: Update Listing of Financial Institutions in Liquidation...

  12. 76 FR 42125 - Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation...

    Science.gov (United States)

    2011-07-18

    ... purposes of the statement of policy published in the July 2, 1992 issue of the Federal Register (57 FR... FEDERAL DEPOSIT INSURANCE CORPORATION Update to Notice of Financial Institutions for Which the...: Federal Deposit Insurance Corporation (FDIC). ACTION: Update Listing of Financial Institutions in...

  13. 76 FR 4113 - Federal Procurement Data System Product Service Code Manual Update

    Science.gov (United States)

    2011-01-24

    ... From the Federal Register Online via the Government Publishing Office GENERAL SERVICES ADMINISTRATION Federal Procurement Data System Product Service Code Manual Update AGENCY: Office of Governmentwide Policy, General Services Administration (GSA). ACTION: Notice. SUMMARY: This notice announces that...

  14. 48 CFR 1804.470-2 - Policy.

    Science.gov (United States)

    2010-10-01

    ...) 2810, Security of Information Technology; NASA Procedural Requirements (NPR) 2810, Security of Information Technology; and interim policy updates in the form of NASA Information Technology Requirements... ADMINISTRATIVE MATTERS Safeguarding Classified Information Within Industry 1804.470-2 Policy. NASA IT security...

  15. Process Coordination & Policy Officer | IDRC - International ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    When a policy requires updating, the applicable level of management will provide the incumbent with operational and other relevant information; the incumbent will provide Division management with information on current trends and the results of research. Together they will develop the parameters for the policy work that ...

  16. Time to update and quantitative changes in the results of cochrane pregnancy and childbirth reviews.

    Directory of Open Access Journals (Sweden)

    Wanlop Jaidee

    Full Text Available BACKGROUND: The recommended interval between updates for systematic reviews included in The Cochrane Library is 2 years. However, it is unclear whether this interval is always appropriate. Whereas excessive updating wastes time and resources, insufficient updating allows out-of-date or incomplete evidence to guide clinical decision-making. We set out to determine, for Cochrane pregnancy and childbirth reviews, the frequency of updates, factors associated with updating, and whether updating frequency was appropriate. METHODOLOGY/PRINCIPAL FINDINGS: Cochrane pregnancy and childbirth reviews published in Issue 3, 2007 of the Cochrane Database of Systematic Reviews were retrieved, and data were collected from their original and updated versions. Quantitative changes were determined for one of the primary outcomes (mortality, or the outcome of greatest clinical significance. Potential factors associated with time to update were assessed using the Cox proportional hazard model. Among the 101 reviews in our final sample, the median time before the first update was 3.3 years (95% CI 2.7-3.8. Only 32.7% had been updated within the recommended interval of 2 years. In 75.3% (76/101, a median of 3 new trials with a median of 576 additional participants were included in the updated versions. There were quantitative changes in 71% of the reviews that included new trials (54/76: the median change in effect size was 18.2%, and the median change in 95% CI width was 30.8%. Statistical significance changed in 18.5% (10/54 of these reviews, but conclusions were revised in only 3.7% (2/54. A shorter time to update was associated with the same original review team at updating. CONCLUSIONS/SIGNIFICANCE: Most reviews were updated less frequently than recommended by Cochrane policy, but few updates had revised conclusions. Prescribed time to update should be reconsidered to support improved decision-making while making efficient use of limited resources.

  17. Sequence History Update Tool

    Science.gov (United States)

    Khanampompan, Teerapat; Gladden, Roy; Fisher, Forest; DelGuercio, Chris

    2008-01-01

    The Sequence History Update Tool performs Web-based sequence statistics archiving for Mars Reconnaissance Orbiter (MRO). Using a single UNIX command, the software takes advantage of sequencing conventions to automatically extract the needed statistics from multiple files. This information is then used to populate a PHP database, which is then seamlessly formatted into a dynamic Web page. This tool replaces a previous tedious and error-prone process of manually editing HTML code to construct a Web-based table. Because the tool manages all of the statistics gathering and file delivery to and from multiple data sources spread across multiple servers, there is also a considerable time and effort savings. With the use of The Sequence History Update Tool what previously took minutes is now done in less than 30 seconds, and now provides a more accurate archival record of the sequence commanding for MRO.

  18. Net Zero Water Update

    Science.gov (United States)

    2011-05-12

    Update 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7...Opened to Collect Supplemental Data from Candidate Installations 15 Mar 11 Supplemental Data received from Army Commands 16-31 Mar 11 DOE...hierarchy (reduction, re-purpose, recycling & composting , energy recovery, and disposal) • Complied with Net Zero definitions • Demonstrated

  19. Ontario Hydro's DSP update

    International Nuclear Information System (INIS)

    Anon.

    1992-01-01

    Ontario Hydro's Demand/Supply Plan (DSP), the 25 year plan which was submitted in December 1989, is currently being reviewed by the Environmental Assessment Board (EAB). Since 1989 there have been several changes which have led Ontario Hydro to update the original Demand/Supply Plan. This information sheet gives a quick overview of what has changed and how Ontario Hydro is adapting to that change

  20. Update History of This Database - Trypanosomes Database | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available List Contact us Trypanosomes Database Update History of This Database Date Update contents 2014/05/07 The co...ntact information is corrected. The features and manner of utilization of the database are corrected. 2014/02/04 Trypanosomes Databas...e English archive site is opened. 2011/04/04 Trypanosomes Database ( http://www.tan...paku.org/tdb/ ) is opened. About This Database Database Description Download Lice...nse Update History of This Database Site Policy | Contact Us Update History of This Database - Trypanosomes Database | LSDB Archive ...

  1. Web Browser Security Update Effectiveness

    Science.gov (United States)

    Duebendorfer, Thomas; Frei, Stefan

    We analyze the effectiveness of different Web browser update mechanisms on various operating systems; from Google Chrome's silent update mechanism to Opera's update requiring a full re-installation. We use anonymized logs from Google's world wide distributed Web servers. An analysis of the logged HTTP user-agent strings that Web browsers report when requesting any Web page is used to measure the daily browser version shares in active use. To the best of our knowledge, this is the first global scale measurement of Web browser update effectiveness comparing four different Web browser update strategies including Google Chrome. Our measurements prove that silent updates and little dependency on the underlying operating system are most effective to get users of Web browsers to surf the Web with the latest browser version.

  2. Astrophysics Update 2

    CERN Document Server

    Mason, John W

    2006-01-01

    "Astrophysics Updates" is intended to serve the information needs of professional astronomers and postgraduate students about areas of astronomy, astrophysics and cosmology that are rich and active research spheres. Observational methods and the latest results of astronomical research are presented as well as their theoretical foundations and interrelations. The contributed commissioned articles are written by leading exponents in a format that will appeal to professional astronomers and astrophysicists who are interested in topics outside their own specific areas of research. This collection of timely reviews may also attract the interest of advanced amateur astronomers seeking scientifically rigorous coverage.

  3. Radiotherapy: An Update

    Directory of Open Access Journals (Sweden)

    Vikrant Kasat

    2010-01-01

    Full Text Available Radiotherapy is the art of using ionizing radiation to destroy malignant cells while minimizing damage to normal tissue. Radiotherapy has become a standard treatment option for a wide range of malignancies. Several new imaging techniques, both anatomical and functional are currently being evaluated as well as practiced for treatment planning of cancer. These recent developments have allowed radiation oncologists to escalate the dose of radiation delivered to tumors while minimizing the dose delivered to surrounding normal tissue. In this update, we attempt to pen down important aspects of radiotherapy.

  4. Hypokalemia: a clinical update

    Directory of Open Access Journals (Sweden)

    Efstratios Kardalas

    2018-04-01

    Full Text Available Hypokalemia is a common electrolyte disturbance, especially in hospitalized patients. It can have various causes, including endocrine ones. Sometimes, hypokalemia requires urgent medical attention. The aim of this review is to present updated information regarding: (1 the definition and prevalence of hypokalemia, (2 the physiology of potassium homeostasis, (3 the various causes leading to hypokalemia, (4 the diagnostic steps for the assessment of hypokalemia and (5 the appropriate treatment of hypokalemia depending on the cause. Practical algorithms for the optimal diagnostic, treatment and follow-up strategy are presented, while an individualized approach is emphasized.

  5. Context updates are hierarchical

    Directory of Open Access Journals (Sweden)

    Anton Karl Ingason

    2016-10-01

    Full Text Available This squib studies the order in which elements are added to the shared context of interlocutors in a conversation. It focuses on context updates within one hierarchical structure and argues that structurally higher elements are entered into the context before lower elements, even if the structurally higher elements are pronounced after the lower elements. The crucial data are drawn from a comparison of relative clauses in two head-initial languages, English and Icelandic, and two head-final languages, Korean and Japanese. The findings have consequences for any theory of a dynamic semantics.

  6. WIMS Library updating

    International Nuclear Information System (INIS)

    Ravnik, M.; Trkov, A.; Holubar, A.

    1992-01-01

    At the end of 1990 the WIMS Library Update Project (WLUP) has been initiated at the International Atomic Energy Agency. The project was organized as an international research project, coordinated at the J. Stefan Institute. Up to now, 22 laboratories from 19 countries joined the project. Phase 1 of the project, which included WIMS input optimization for five experimental benchmark lattices, has been completed. The work presented in this paper describes also the results of Phase 2 of the Project, in which the cross sections based on ENDF/B-IV evaluated nuclear data library have been processed. (author) [sl

  7. Tough Policies, Incredible Policies?

    OpenAIRE

    Andres Velasco; Alejandro Neut

    2003-01-01

    We revisit the question of what determines the credibility of macroeconomic policies here, of promises to repay public debt. Almost all thinking on the issue has focused on governments' strategic decision to default (or erode the value of outstanding debt via inflation/devaluation). But sometimes governments default not because they want to, but because they cannot avoid it: adverse shocks leave them no option. We build a model in which default/devaluation can occur deliberately (for strategi...

  8. 75 FR 4391 - Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation...

    Science.gov (United States)

    2010-01-27

    ... 12 U.S.C. 1825(b)(2) and 28 U.S.C. 2410(c). The policy statement and an initial listing of financial... receiver for purposes of the statement of policy. For information concerning the identification of any... FEDERAL DEPOSIT INSURANCE CORPORATION Update to Notice of Financial Institutions for Which the...

  9. China's Health Reform Update.

    Science.gov (United States)

    Liu, Gordon G; Vortherms, Samantha A; Hong, Xuezhi

    2017-03-20

    China experienced both economic and epistemological transitions within the past few decades, greatly increasing demand for accessible and affordable health care. These shifts put significant pressure on the existing outdated, highly centralized bureaucratic system. Adjusting to growing demands, the government has pursued a new round of health reforms since the late 2000s; the main goals are to reform health care financing, essential drug policies, and public hospitals. Health care financing reform led to universal basic medical insurance, whereas the public hospital reform required more complex measures ranging from changes in regulatory, operational, and service delivery settings to personnel management. This article reviews these major policy changes and the literature-based evidence of the effects of reforms on cost, access, and quality of care. It then highlights the outlook for future reforms. We argue that a better understanding of the unintended consequences of reform policies and of how practitioners' and patients' interests can be better aligned is essential for reforms to succeed.

  10. Memory Updating and Mental Arithmetic.

    Science.gov (United States)

    Han, Cheng-Ching; Yang, Tsung-Han; Lin, Chia-Yuan; Yen, Nai-Shing

    2016-01-01

    Is domain-general memory updating ability predictive of calculation skills or are such skills better predicted by the capacity for updating specifically numerical information? Here, we used multidigit mental multiplication (MMM) as a measure for calculating skill as this operation requires the accurate maintenance and updating of information in addition to skills needed for arithmetic more generally. In Experiment 1, we found that only individual differences with regard to a task updating numerical information following addition (MUcalc) could predict the performance of MMM, perhaps owing to common elements between the task and MMM. In Experiment 2, new updating tasks were designed to clarify this: a spatial updating task with no numbers, a numerical task with no calculation, and a word task. The results showed that both MUcalc and the spatial task were able to predict the performance of MMM but only with the more difficult problems, while other updating tasks did not predict performance. It is concluded that relevant processes involved in updating the contents of working memory support mental arithmetic in adults.

  11. Memory updating and mental arithmetic

    Directory of Open Access Journals (Sweden)

    Cheng-Ching eHan

    2016-02-01

    Full Text Available Is domain-general memory updating ability predictive of calculation skills or are such skills better predicted by the capacity for updating specifically numerical information? Here, we used multidigit mental multiplication (MMM as a measure for calculating skill as this operation requires the accurate maintenance and updating of information in addition to skills needed for arithmetic more generally. In Experiment 1, we found that only individual differences with regard to a task updating numerical information following addition (MUcalc could predict the performance of MMM, perhaps owing to common elements between the task and MMM. In Experiment 2, new updating tasks were designed to clarify this: a spatial updating task with no numbers, a numerical task with no calculation, and a word task. The results showed that both MUcalc and the spatial task were able to predict the performance of MMM but only with the more difficult problems, while other updating tasks did not predict performance. It is concluded that relevant processes involved in updating the contents of working memory support mental arithmetic in adults.

  12. Updates in ophthalmic pathology.

    Science.gov (United States)

    Mendoza, Pia R; Grossniklaus, Hans E

    2017-05-01

    Ophthalmic pathology has a long history and rich heritage in the field of ophthalmology. This review article highlights updates in ophthalmic pathology that have developed significantly through the years because of the efforts of committed individuals and the confluence of technology such as molecular biology and digital pathology. This is an exciting period in the history of ocular pathology, with cutting-edge techniques paving the way for new developments in diagnostics, therapeutics, and research. Collaborations between ocular oncologists and pathologists allow for improved and comprehensive patient care. Ophthalmic pathology continues to be a relevant specialty that is important in the understanding and clinical management of ocular disease, education of eye care providers, and overall advancement of the field.

  13. Updates in ophthalmic pathology

    Directory of Open Access Journals (Sweden)

    Pia R Mendoza

    2017-01-01

    Full Text Available Ophthalmic pathology has a long history and rich heritage in the field of ophthalmology. This review article highlights updates in ophthalmic pathology that have developed significantly through the years because of the efforts of committed individuals and the confluence of technology such as molecular biology and digital pathology. This is an exciting period in the history of ocular pathology, with cutting-edge techniques paving the way for new developments in diagnostics, therapeutics, and research. Collaborations between ocular oncologists and pathologists allow for improved and comprehensive patient care. Ophthalmic pathology continues to be a relevant specialty that is important in the understanding and clinical management of ocular disease, education of eye care providers, and overall advancement of the field.

  14. Geothermal Greenhouse Development Update

    Energy Technology Data Exchange (ETDEWEB)

    Lienau, Paul J.

    1997-01-01

    Greenhouse heating is one of the popular applications of low-to moderated-temperature geothermal resources. Using geothermal energy is both an economical and efficient way to heat greenhouses. Greenhouse heating systems can be designed to utilize low-temperature (>50oC or 122oF) resources, which makes the greenhouse an attractive application. These resources are widespread throughout the western states providing a significant potential for expansion of the geothermal greenhouse industry. This article summarizes the development of geothermal heated greenhouses, which mainly began about the mid-1970's. Based on a survey (Lienau, 1988) conducted in 1988 and updated in 1997, there are 37 operators of commercial greenhouses. Table 1 is a listing of known commercial geothermal greenhouses, we estimate that there may be an additional 25% on which data is not available.

  15. [Update Chagas disease].

    Science.gov (United States)

    Molina, Israel; Salvador, Fernando; Sánchez-Montalvá, Adrián

    2016-02-01

    The constant migration flows have favored the presence of people with Chagas disease in regions traditionally regarded as non-endemic, such as North America, Europe, Asia and Oceania. This has forced both health authorities and professionals to be updated in order to respond to such a demand for assistance. Recent years have led to significant progress in the field of diagnosis and treatment of Chagas disease, one of the most neglected tropical diseases. Recent clinical trials are providing new evidence that makes the management of these patients, a constant challenge for the professionals involved. Innovative diagnostic tools and therapeutic regimens, allow us to face the future of Chagas disease with optimism. Copyright © 2016 Elsevier España, S.L.U. y Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved.

  16. Y2K UPDATE

    CERN Multimedia

    Sverre JARP

    1999-01-01

    Concerning Y2K preparation, please note the following:Everybody, who has a NICE installation on his/her PC, needs to log in to NICE at least once before Xmas to get the Y2K update installed. This applies especially to dual boot systems.The test schedule on Y2Kplus.cern.ch will be prolonged. The last restart took place on 10 November and two more will take place on 24 November and 8 December, respectively. The Oracle users responsible for the maintenance of Oracle Forms applications which include PL/SQL blocks where date fields are handled with the default format are requested to contact oracle.support@cern.ch at their earliest convenience.Sverre Jarp (CERN Y2K co-ordinator, phone: 74944)

  17. Amblyopia update: new treatments.

    Science.gov (United States)

    Vagge, Aldo; Nelson, Leonard B

    2016-09-01

    This review article is an update on the current treatments for amblyopia. In particular, the authors focus on the concepts of brain plasticity and their implications for novel treatment strategies for both children and adults affected by amblyopia. A variety of strategies has been developed to treat amblyopia in children and adults. New evidence on the pathogenesis of amblyopia has been obtained both in animal models and in clinical trials. Mainly, these studies have challenged the classical concept that amblyopia becomes untreatable after the 'end' of the sensitive or critical period of visual development, because of a lack of sufficient plasticity in the adult brain. New treatments for amblyopia in children and adults are desirable and should be encouraged. However, further studies should be completed before such therapies are widely accepted into clinical practice.

  18. Update in urethral stents.

    Science.gov (United States)

    Bahouth, Z; Meyer, G; Yildiz, G; Nativ, O; Moskovitz, B

    2016-10-01

    Urethral stents were first introduced in 1988, and since then, they have undergone significant improvements. However, they did not gain a wide popularity and their use is limited to a small number of centers around the world. Urethral stents can be used in the entire urethra and for various and diverse indications. In the anterior urethra, it can be used to treat urethral strictures. In the prostatic urethra, they can be used for the treatment of prostatic obstruction, including benign, malignant and iatrogenic prostatic obstruction. Moreover, although not widely used, it can be also applied for the treatment of posterior urethral stricture and bladder neck contracture, usually resulting in urinary incontinence and the need for subsequent procedures. Our main experience are with Allium urethral stents, and as such, we provide the latest updates in urethral stents with special emphasis on the various types of Allium urethral stents: bulbar, prostatic and bladder neck stents.

  19. Update on equine allergies.

    Science.gov (United States)

    Fadok, Valerie A

    2013-12-01

    Horses develop many skin and respiratory disorders that have been attributed to allergy. These disorders include pruritic skin diseases, recurrent urticaria, allergic rhinoconjunctivitis, and reactive airway disease. Allergen-specific IgE has been detected in these horses, and allergen-specific immunotherapy is used to ameliorate clinical signs. The best understood atopic disease in horses is insect hypersensitivity, but the goal of effective treatment with allergen-specific immunotherapy remains elusive. In this review, updates in pathogenesis of allergic states and a brief mention of the new data on what is known in humans and dogs and how that relates to equine allergic disorders are discussed. Copyright © 2013 Elsevier Inc. All rights reserved.

  20. AOS clearwater project update

    Energy Technology Data Exchange (ETDEWEB)

    Palmgren, Claes [Alberta Oilsands Inc (Canada)

    2011-07-01

    The Athabasca oil sands, located in northeastern Alberta, are one of the largest deposits of bitumen in the world. In this presentation Alberta Oilsands Inc. provides an update of their two phase Clearwater project which aims at using an SLP-SAGD system to recover Athabasca bitumen. The Clearwater project site is located nearby the Fort McMurray regional airport. The idea behind the project is to utilize a low pressure SAGD system in combination with a co-injected solvent in order to extract the bitumen. The injected solvent mixes with the bitumen, decreasing its viscosity and improving its ability to flow. This type of system requires only 1000 kPa of operating pressure which leads to a lower steam to oil ratio. By the end of phase one, the Clearwater project aims at bringing in 4,500 barrels of oil per day (BOPD) and 15,000 to 25,000 BOPD by the end of phase two.

  1. Cohort Profile Update

    DEFF Research Database (Denmark)

    Omland, Lars Haukali; Ahlström, Magnus Glindvad; Obel, Niels

    2014-01-01

    of Causes of Death, the Danish National Prescription Registry, the Attainment Register and the Integrated Database for Labour Market Research to get information on vital status, migration, cancer, hospital contacts, causes of death, dispensed prescriptions, education and employment. Using this design, rates......The DHCS is a cohort of all HIV-infected individuals seen in one of the eight Danish HIV centres after 31 December 1994. Here we update the 2009 cohort profile emphasizing the development of the cohort. Every 12-24 months, DHCS is linked with the Danish Civil Registration System (CRS) in order...... to extract an age- and sex-matched comparison cohort from the general population, as well as cohorts of family members of the HIV-infected patients and of the comparison cohort. The combined cohort is linked with CRS, the Danish Cancer Registry, the Danish National Hospital Registry, the Danish Registry...

  2. ADAS Update and Maintainability

    Science.gov (United States)

    Watson, Leela R.

    2010-01-01

    Since 2000, both the National Weather Service Melbourne (NWS MLB) and the Spaceflight Meteorology Group (SMG) have used a local data integration system (LOIS) as part of their forecast and warning operations. The original LOIS was developed by the Applied Meteorology Unit (AMU) in 1998 (Manobianco and Case 1998) and has undergone subsequent improvements. Each has benefited from three-dimensional (3-D) analyses that are delivered to forecasters every 15 minutes across the peninsula of Florida. The intent is to generate products that enhance short-range weather forecasts issued in support of NWS MLB and SMG operational requirements within East Central Florida. The current LDIS uses the Advanced Regional Prediction System (ARPS) Data Analysis System (AD AS) package as its core, which integrates a wide variety of national, regional, and local observational data sets. It assimilates all available real-time data within its domain and is run at a finer spatial and temporal resolution than current national or regional-scale analysis packages. As such, it provides local forecasters with a more comprehensive understanding of evolving fine-scale weather features. Over the years, the LDIS has become problematic to maintain since it depends on AMU-developed shell scripts that were written for an earlier version of the ADAS software. The goals of this task were to update the NWS MLB/SMG LDIS with the latest version of ADAS, incorporate new sources of observational data, and upgrade and modify the AMU-developed shell scripts written to govern the system. In addition, the previously developed ADAS graphical user interface (GUI) was updated. Operationally, these upgrades will result in more accurate depictions of the current local environment to help with short-range weather forecasting applications, while also offering an improved initialization for local versions of the Weather Research and Forecasting (WRF) model used by both groups.

  3. Oil sands development update

    International Nuclear Information System (INIS)

    1999-01-01

    A detailed review and update of oil sands development in Alberta are provided covering every aspect of the production and economic aspects of the industry. It is pointed out that at present oil sands account for 28 per cent of Canadian crude oil production, expected to reach 50 per cent by 2005. Based on recent announcements, a total of 26 billion dollars worth of projects are in progress or planned; 20 billion dollars worth of this development is in the Athabasca area, the remainder in Cold Lake and other areas. The current update envisages up to 1,800,000 barrels per day by 2008, creating 47,000 new jobs and total government revenues through direct and indirect taxes of 118 billion dollars. Provinces other than Alberta also benefit from these development, since 60 per cent of all employment and income created by oil sands production is in other parts of Canada. Up to 60 per cent of the expansion is for goods and services and of this, 50 to 55 per cent will be purchased from Canadian sources. The remaining 40 per cent of the new investment is for engineering and construction of which 95 per cent is Canadian content. Aboriginal workforce by common consent of existing operators matches regional representation (about 13 per cent), and new developers are expected to match these standards. Planned or ongoing development in environmental protection through improved technologies and optimization, energy efficiency and improved tailings management, and active support of flexibility mechanisms such as emission credits trading, joint implementation and carbon sinks are very high on the industry's agenda. The importance of offsets are discussed extensively along with key considerations for international negotiations, as well as further research of other options such as sequestration, environmentally benign disposal of waste, and enhanced voluntary action

  4. Updated WHO guidance on safe abortion: health and human rights.

    Science.gov (United States)

    Erdman, Joanna N; DePiñeres, Teresa; Kismödi, Eszter

    2013-02-01

    Since its first publication in 2003, the World Health Organization's "Safe abortion: technical and policy guidance for health systems" has had an influence on abortion policy, law, and practice worldwide. To reflect significant developments in the clinical, service delivery, and human rights aspects of abortion care, the Guidance was updated in 2012. This article reviews select recommendations of the updated Guidance, highlighting 3 key themes that run throughout its chapters: evidence-based practice and assessment, human rights standards, and a pragmatic orientation to safe and accessible abortion care. These themes not only connect the chapters into a coherent whole. They reflect the research and advocacy efforts of a growing field in women's health and human rights. Copyright © 2012 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.

  5. Update of CERN exchange network

    CERN Multimedia

    2003-01-01

    An update of the CERN exchange network will be done next April. Disturbances or even interruptions of telephony services may occur from 4th to 24th April during evenings from 18:30 to 00:00 but will not exceed more than 4 consecutive hours (see tentative planning below). CERN divisions are invited to avoid any change requests (set-ups, move or removals) of telephones and fax machines from 4th to 25th April. Everything will be done to minimize potential inconveniences which may occur during this update. There will be no loss of telephone functionalities. CERN GSM portable phones won't be affected by this change. Should you need more details, please send us your questions by email to Standard.Telephone@cern.ch. DateChange typeAffected areas April 11 Update of switch in LHC 4 LHC 4 Point April 14 Update of switch in LHC 5 LHC 5 Point April 15 Update of switches in LHC 3 and LHC 2 Points LHC 3 and LHC 2 April 22 Update of switch N4 Meyrin Ouest April 23 Update of switch  N6 Prévessin Site Ap...

  6. The policies

    International Nuclear Information System (INIS)

    Laruelle, Ph.; Snegaroff, Th.; Moreau, S.; Tellenne, C.; Brunel, S.

    2005-01-01

    Fourth chapter of the book on the geo-policy of the sustainable development, this chapter deal with the different and international policies concerned by the problem. The authors analyze the american energy attitude and policy, the economical equilibrium facing the environmental equilibrium for the european policy, the sanctified and sacrificed nature and the japanese attitude, India and China, the great fear of the 21 century and the sustainable development in Africa. (A.L.B.)

  7. Multiplicative updates for the LASSO

    DEFF Research Database (Denmark)

    Mørup, Morten; Clemmensen, Line Katrine Harder

    2007-01-01

    .e. least squares minimization with $L_1$-norm regularization, since the multiplicative updates (MU) can efficiently exploit the structure of the problem traditionally solved using quadratic programming (QP). We derive an algorithm based on MU for the LASSO and compare the performance to Matlabs standard QP......Multiplicative updates have proven useful for non-negativity constrained optimization. Presently, we demonstrate how multiplicative updates also can be used for unconstrained optimization. This is for instance useful when estimating the least absolute shrinkage and selection operator (LASSO), i...

  8. Updating optical pseudoinverse associative memories.

    Science.gov (United States)

    Telfer, B; Casasent, D

    1989-07-01

    Selected algorithms for adding to and deleting from optical pseudoinverse associative memories are presented and compared. New realizations of pseudoinverse updating methods using vector inner product matrix bordering and reduced-dimensionality Karhunen-Loeve approximations (which have been used for updating optical filters) are described in the context of associative memories. Greville's theorem is reviewed and compared with the Widrow-Hoff algorithm. Kohonen's gradient projection method is expressed in a different form suitable for optical implementation. The data matrix memory is also discussed for comparison purposes. Memory size, speed and ease of updating, and key vector requirements are the comparison criteria used.

  9. Tetraplegia Management Update.

    Science.gov (United States)

    Fridén, Jan; Gohritz, Andreas

    2015-12-01

    Tetraplegia is a profound impairment of mobility manifesting as a paralysis of all 4 extremities owing to cervical spinal cord injury. The purpose of this article is to provide an update and analyze current management, treatment options, and outcomes of surgical reconstruction of arm and hand function. Surgical restoration of elbow and wrist extension or handgrip has tremendous potential to improve autonomy, mobility, and critical abilities, for example, eating, personal care, and self-catheterization and productive work in at least 70% of tetraplegic patients. Tendon and nerve transfers, tenodeses, and joint stabilizations reliably enable improved arm and hand usability, reduce muscle imbalance and pain in spasticity, and prevent joint contractures. One-stage combined procedures have proven considerable advantages over traditional multistage approaches. Immediate activation of transferred muscles reduces the risk of adhesions, facilitates relearning, avoids adverse effects of immobilization, and enhances functional recovery. Transfer of axillary, musculocutaneous, and radial nerve fascicles from above the spinal cord injury are effective and promising options to enhance motor outcome and sensory protection, especially in groups with limited resources. Improved communication between medical disciplines, therapists, patients, and their relatives should help that more individuals can benefit from these advances and could empower many thousands tetraplegic individuals "to take life into their own hands" and live more independently. Copyright © 2015 American Society for Surgery of the Hand. Published by Elsevier Inc. All rights reserved.

  10. Scabies: A clinical update.

    Science.gov (United States)

    Hardy, Myra; Engelman, Daniel; Steer, Andrew

    2017-01-01

    Scabies is a common, yet neglected, skin disease. Scabies occurs across Australia, but most frequently in socioeconomically disadvantaged populations in tropical regions, including in remote Aboriginal and Torres Strait Islander communities. In temperate settings, the disease clusters in institutional care facilities. The objective of this article is to provide updates on the clinical diagnosis and treatment approaches for scabies in Australia. Clinical examination remains the mainstay of diagnosis, although dermatoscopy is a useful adjunct. Scabies presents with severe itch and a papular rash, with a predilection for the hands, feet and genitalia. The distribution may be more widespread in infants and older people. Secondary bacterial infection is also common in patients with scabies. Crusted scabies is a rare but highly infectious variant. Topical permethrin is highly effective for individual treatment, but less practical for treatment of asymptomatic contacts and control of outbreaks. Oral ivermectin is a safe and effective alternative, and is now listed on the Pharmaceutical Benefits Scheme as a third-line treatment.

  11. Updates on obesity pharmacotherapy.

    Science.gov (United States)

    Velazquez, Amanda; Apovian, Caroline M

    2018-01-01

    Obesity is a chronic, relapsing disease that necessitates a multidisciplinary approach to management. Behavioral changes are the foundation to management, but adjunctive therapy is often warranted, including pharmacologic therapies and/or bariatric surgery. Until recently, treatment options included only short-term therapy (≤12 weeks), and paths beyond that schedule were challenging, as knowledge of the biology of obesity was lacking. With increased recognition of obesity as a chronic, complex medical disease, newer agents have been approved as long-term therapy, and the cornerstone of treatment is chronic behavior and lifestyle change. In the last decade, the Food and Drug Administration (FDA) has approved several new weight loss medications for the chronic management of obesity. In this review paper, we provide the latest updates on obesity pharmacotherapy. The main areas we will cover include (1) pharmacological management of obesity, (2) a review of FDA-approved weight loss medications, (3) comanagement of obesity and its metabolic sequelae (type 2 diabetes mellitus, hypertension, and dyslipidemia), and (4) obesity-centric prescribing for mental illness, neurological disorders, and contraceptive planning. © 2018 New York Academy of Sciences.

  12. Peritoneal dialysis update 1994.

    Directory of Open Access Journals (Sweden)

    Nolph K

    1994-07-01

    Full Text Available Each year there are over 400 papers published in the field of peritoneal dialysis. In this review I have touched on only a few highlights of some of the more active areas of investigation and development. The advances in controlling peritonitis rates with the Y-set have been dramatic and have resulted in peritonitis rates in many centers less than one episode per 24 patient months. Technique survivals have also improved with lower peritonitis rates. The enormous literature on new approaches to treatment and new understandings of host defenses are beyond the scope of this review. There are also many advances in peritoneal access. We now have many new types of catheters under investigation such as the Swan-Neck Missouri catheter and the Moncrief-Popovich catheter, with complete burial of the catheter until eventual externalization for CAPD training. There have been major advances in understanding the normal healing of exit sites and the early diagnosis and treatment of exit-site infections. All the extensive literature on catheter development in the management of exit sites will be reviewed elsewhere. I have focused primarily on an update of worldwide demographics, some of the new findings in peritoneal transport, the use of low-calcium solutions, experiences with EPO, new thinking about adequacy and nutrition, and finally, on recent comparisons of CAPD and hemodialysis.

  13. Dali server update.

    Science.gov (United States)

    Holm, Liisa; Laakso, Laura M

    2016-07-08

    The Dali server (http://ekhidna2.biocenter.helsinki.fi/dali) is a network service for comparing protein structures in 3D. In favourable cases, comparing 3D structures may reveal biologically interesting similarities that are not detectable by comparing sequences. The Dali server has been running in various places for over 20 years and is used routinely by crystallographers on newly solved structures. The latest update of the server provides enhanced analytics for the study of sequence and structure conservation. The server performs three types of structure comparisons: (i) Protein Data Bank (PDB) search compares one query structure against those in the PDB and returns a list of similar structures; (ii) pairwise comparison compares one query structure against a list of structures specified by the user; and (iii) all against all structure comparison returns a structural similarity matrix, a dendrogram and a multidimensional scaling projection of a set of structures specified by the user. Structural superimpositions are visualized using the Java-free WebGL viewer PV. The structural alignment view is enhanced by sequence similarity searches against Uniprot. The combined structure-sequence alignment information is compressed to a stack of aligned sequence logos. In the stack, each structure is structurally aligned to the query protein and represented by a sequence logo. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

  14. Gambling in Spain: update on experience, research and policy.

    Science.gov (United States)

    Jiménez-Murcia, Susana; Fernández-Aranda, Fernando; Granero, Roser; Menchón, Jose Manuel

    2014-10-01

    To describe the current situation of gambling in Spain, sketching its history and discussing the regulations and legislation currently in force within the framework of the European Union (EU), and to review the epidemiology of gambling in Spain, the self-help groups and professional treatments available, and their potential effectiveness. A systematic computerized search was performed in three databases (EMBASE, PubMed and PsychINFO, including articles and chapters) and the reference lists from previous reviews to obtain some of the most relevant studies published up to now on the topic of pathologic gambling in Spain. Similar to other EU countries, Spain has a high prevalence of pathologic gambling, focused on specific culturally bounded types of gambling. Expenditure in online gaming has risen significantly in the last few years, prompting the Spanish government to draft new legislation to regulate gaming. The gaming industry is expected to be one of the fastest growing sectors in Spain in the coming years owing to the rise of new technologies and the development of online gaming. © 2013 Society for the Study of Addiction.

  15. ESSA and Homeless Youth. Policy Update. Vol. 23, No. 18

    Science.gov (United States)

    Parsi, Ace; Duffield, Barbara

    2016-01-01

    As state and district leaders evaluate characteristics of their student populations, many will find one number particularly startling: The number of homeless students has doubled in less than a decade. States can take several actions to serve these students better, some of which are incorporated in the Every Student Succeeds Act (ESSA). Some of…

  16. Oil and Gas Emergency Policy: Chile 2012 update

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-09-06

    Chile has experienced several serious energy supply incidents over the last decade, including major droughts, a sustained gas supply cut from Argentina (since 2004), and a major earthquake in early 2010 which affected electricity networks and refineries, and caused several black-outs. Due to Chile's unique and sinuous geography - it runs 4 300 kilometres from North to South and only 175 kms from East to West- the country's energy markets are regionally disjointed, particularly as the regional gas and electricity grids are not connected. In the arid North, energy demand is dominated by the mining industry, and operates based on a separate thermal-based Sistema Interconectado Norte Grande (SING) electricity grid. The more densely-populated central region (including Santiago) operates on the more hydro-dependent Sistema Interconectado Central (SIC) electricity grid. The southernmost, hydro-rich regions of the country are not connected to the rest of Chile in terms of electricity and gas. The following report is based on an IEA Emergency Response Assessment carried out in 2010 and 2011 which looked specifically at Chile's capacity to respond to short-term emergencies in oil, gas and electricity.

  17. General equilibrium basic needs policy model, (updating part).

    OpenAIRE

    Kouwenaar A

    1985-01-01

    ILO pub-WEP pub-PREALC pub. Working paper, econometric model for the assessment of structural change affecting development planning for basic needs satisfaction in Ecuador - considers population growth, family size (households), labour force participation, labour supply, wages, income distribution, profit rates, capital ownership, etc.; examines nutrition, education and health as factors influencing productivity. Diagram, graph, references, statistical tables.

  18. Oil and Gas Emergency Policy: Germany 2012 update

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-07-01

    Germany has very little domestic oil and natural gas production and relies heavily on imports. It has well diversified and flexible oil and natural gas supply infrastructure, which consists of crude, product and gas pipelines and crude and oil product import terminals. Natural gas is imported into Germany exclusively by cross-border pipeline. The country has no LNG infrastructure, although some German companies have booked capacities in overseas LNG terminals. Oil continues to be the main source of energy in Germany although it has declined markedly since the early 1970s. It now represents approximately 32% of Germany’s total primary energy supply (TPES). Natural gas consumption in Germany has declined 10% since 2006. Demand was 90 bcm in 2010, down from 100 bcm in 2005. According to government commissioned analysis, the total consumption of natural gas in Germany is expected to continue to decline over the long term. The share of natural gas in Germany’s TPES is currently around 22%. German oil stock levels are generally well above the required 90-days. Total oil stock levels in Germany were equivalent to 140 days net imports in April 2012. Since 1998, the German oil stockholding agency (EBV) has been solely responsible for meeting Germany's 90-day stockholding obligation. The Oil Stockholding Act stipulates that the EBV shall constantly maintain stocks of oil and petroleum products at a level equivalent to or above 90 days of net imports. There is no minimum stockholding obligation on industry, so industry held commercial stocks are held in addition to the EBV stocks. There are several legal tools available to German authorities for natural gas emergency response. These include Ordinances that can be used to restrict the sale, purchase or use of goods, both in terms of quantity and time, or permit them only for certain priority purposes, to ensure that vital energy needs are met. There are no compulsory natural gas storage requirements in Germany, and no state-owned storage facilities. Operators of gas storage facilities must grant other companies access to their storage facilities and auxiliary services at a fair market price. There are 47 gas storage facilities in Germany, with a total capacity 20.9 bcm. German firms also have access to natural gas storage in Haidach (Austria) which has a capacity of 2.6 bcm.

  19. Internet Journal of Medical Update - EJOURNAL: Editorial Policies

    African Journals Online (AJOL)

    ... current ideas in form of review articles, original research work, interesting case reports, etc. among medical professionals. It is also intended to provide a platform for young medical professionals to participate in research activities, with the aim to enhance their outlook towards recent developments in the field of medicine.

  20. Genomics and Health Impact Update

    Science.gov (United States)

    ... Alzheimer’s Disease Autism Breast Cancer Cardiomyopathy Colorectal Cancer Diabetes Familial Hypercholesterolemia Heart Disease Hepatitis HIV/AIDS Influenza Listeriosis Lynch Syndrome Malaria Osteoporosis Sudden Death Tuberculosis Zika Virus Updates on Specific Topics Big Data ...

  1. Argonne Wakefield Accelerator Update '92

    International Nuclear Information System (INIS)

    Rosing, M.; Balka, L.; Chojnacki, E.; Gai, W.; Ho, C.; Konecny, R.; Power, J.; Schoessow, P.; Simpson, J.

    1992-01-01

    The Argonne Wakefield Accelerator (AWA) is an experiment designed to test various ideas related to wakefield technology. Construction is now underway for a 100 nC electron beam in December of 1992. This report updates this progress

  2. Efficient Synthesis of Network Updates

    Science.gov (United States)

    2015-06-17

    Pavol Černý CU Boulder pavol.cerny@colorado.edu Nate Foster Cornell University jnfoster@cs.cornell.edu Abstract Software-defined networking ( SDN ...is revolutionizing the net- working industry, but current SDN programming platforms do not provide automated mechanisms for updating global...configurations on the fly. Implementing updates by hand is challenging for SDN programmers because networks are distributed systems with hun- dreds or thousands

  3. Communication technology update and fundamentals

    CERN Document Server

    Grant, August E

    2010-01-01

    New communication technologies are being introduced at an astonishing rate. Making sense of these technologies is increasingly difficult. Communication Technology Update and Fundamentals is the single best source for the latest developments, trends, and issues in communication technology. Featuring the fundamental framework along with the history and background of communication technologies, Communication Technology Update and Fundamentals, 12th edition helps you stay ahead of these ever-changing and emerging technologies.As always, every chapter ha

  4. Communication technology update and fundamentals

    CERN Document Server

    Grant, August E

    2008-01-01

    New communication technologies are being introduced at an astonishing rate. Making sense of these technologies is increasingly difficult. Communication Technology Update is the single best source for the latest developments, trends, and issues in communication technology. Now in its 11th edition, Communication Technology Update has become an indispensable information resource for business, government, and academia. As always, every chapter has been completely rewritten to reflect the latest developments and market statistics, and now covers mobile computing, dig

  5. Decentralized Consistent Updates in SDN

    KAUST Repository

    Nguyen, Thanh Dang

    2017-04-10

    We present ez-Segway, a decentralized mechanism to consistently and quickly update the network state while preventing forwarding anomalies (loops and blackholes) and avoiding link congestion. In our design, the centralized SDN controller only pre-computes information needed by the switches during the update execution. This information is distributed to the switches, which use partial knowledge and direct message passing to efficiently realize the update. This separation of concerns has the key benefit of improving update performance as the communication and computation bottlenecks at the controller are removed. Our evaluations via network emulations and large-scale simulations demonstrate the efficiency of ez-Segway, which compared to a centralized approach, improves network update times by up to 45% and 57% at the median and the 99th percentile, respectively. A deployment of a system prototype in a real OpenFlow switch and an implementation in P4 demonstrate the feasibility and low overhead of implementing simple network update functionality within switches.

  6. Nova Scotia electricity update

    International Nuclear Information System (INIS)

    Crandlemire, A.L.

    2004-01-01

    This paper provides an update of electricity issues concerning Nova Scotia such as supply, capacity, emission commitments, as well as co-generation and the Electricity Marketplace Governance Committee (EMGC). The goals of the strategy were reliability combined with competitive prices and greater environmental responsibility. The scope of these objectives included new capacity, transmission, renewables and co-generation. Other objectives included encouraging wholesale market competition; meeting reciprocity requirements; and a 50 MW renewable energy target. Recommendations of the EMGC included wholesale market competition; a broader market scope with a cost benefit analysis; Open Access Transmission Tariff (OATT); a scheduling and information system; network integration and a point to point service; and a separation of transmission and generation business units. Other recommendations included an open competitive process for new generation; a consideration of emissions and overall efficiency; a Renewable Energy Portfolio Standard (RPS) to start in 2006; the separation of RPS tags from electricity; and net metering of renewables. These recommendations were accepted in 2003, followed by the new Electricity Act in 2004, which made OATT mandatory, established RPS and opened to the wholesale market. Capacity at present was considered to be tight, with preparations for the new regulations under way. Reductions in air pollution were reported at 25 per cent, with renewable energy projects such as 2 windmills currently under way, as well as various other projects. Opportunities for provincial Atlantic cooperation were identified as being management of reserve requirements; trading of lowest cost electricity; new generation on a regional scale; stronger transmission ties; a system operator; a regional approach to RPS; regional management of air emissions; and regional opportunities for Carbon dioxide reductions. tabs., figs

  7. NB market update

    International Nuclear Information System (INIS)

    Marshall, W. K.

    2004-01-01

    The 2004 New Brunswick proclamation introduced several changes to the industry. This paper presents an update of the current New Brunswick electricity market from the perspective of the recently created New Brunswick System Operator (NBSO). A comparison was made between the modified industry and the previous industry structure. Significant changes included: corporate restructuring and market implementation; the formation of the independent system operator; and an increase in Public Utilities Board regulatory authority. The main objectives of the NBSO were reviewed, including its intention to reliably plan and operate the integrated power system as well as facilitating and operating the electricity market. Details of directors and officers were provided along with a list of legislated functions which included entering agreements with transmitters; provision and procurement of ancillary services; maintenance of integrated system; coordination of external activities; participation with standards authorities; planning and development of transmission; and the facilitation of a competitive market. An outline of the NBSO, Transco and Public Utilities Board relationships were presented. Details of the market advisory committee were outlined, with information concerning contracts, operations and services agreements. Transmission and ancillary services were also discussed, as well as issues concerning interruptible load agreements. A chart of the New Brunswick electricity market structure was presented, along with a market overview including details of capacity, ancillary services and suppliers. Market rules and amendments were presented, as well as market participation guides. Details of generation resource adequacy requirements and the imposition of penalties were outlined. Scheduling and dispatch issues were overviewed, as well as settlement processes, inputs and their sources, including settlements for variances. Future development possibilities included an expansion of

  8. Herpes Labialis: An Update.

    Science.gov (United States)

    Leung, Alexander K C; Barankin, Benjamin

    2017-01-01

    Herpes labialis is characterized by recurrent vesicular eruptions primarily on the lips and perioral skin. The condition is contagious, can cause significant discomfort/pain, and can have an adverse effect on the quality of life. To update the evaluation and treatment of herpes labialis. A PubMed search was completed in Clinical Queries using the key term "herpes labialis". Patents were searched using the key term "herpes labialis" from www.freepatentsonline.com. The diagnosis of herpes labialis is mainly clinical based on classic grouped lesions (papules, vesicles, ulcers) on the lip. Antiviral therapy shortens the duration of pain and discomfort, hastens healing, and reduces viral shedding. Thus, episodic treatment is warranted, especially if the patient desires treatment for cosmetic purposes or for relief of pain. Such treatment needs to be initiated promptly, ideally in the prodromal stage and no later than 48 hours from the onset of lesions to achieve optimal results. Chronic suppressive therapy with oral antiviral agents should be considered for patients with severe or frequent (six or more episodes per year) recurrences. Recent patents related to the management of herpes labialis are also discussed. For episodic treatment, oral antiviral agents, such as acyclovir (Zovirax), valacyclovir (Valtrex) and famciclovir (Famvir), are superior to topical antiviral therapy. Valacyclovir and famciclovir have greater oral bioavailability and are better absorbed than acyclovir, require less frequent dosing, but are more expensive and are not approved for children. Topical antiviral agents such as 5% acyclovir cream/ointment (Zovirax) ± hydrocortisone (Xerese), 1% penciclovir (Denavir) cream, and 50 mg Buccal Adhesive Tablet (ABT-50 mg) can also be used for episodic treatment of herpes labialis. These topical agents are not effective in the prevention of recurrent herpes labialis. For chronic daily suppressive therapy, oral antivirals are the treatment of choice

  9. African Journal of Oral Health: Editorial Policies

    African Journals Online (AJOL)

    c) Update articles surveying the present state of knowledge in selected fields of Dentistry and oral health. d) Critical or analytical reviews in the area of theory, policy, or research in Dentistry. e) Reviews of recently published books or group of books which would be of relevance to the improvement of oral health in Africa.

  10. Malaria Policy Advisory Committee to the WHO: conclusions and recommendations of seventh biannual meeting (March 2015).

    Science.gov (United States)

    2015-08-05

    The Malaria Policy Advisory Committee to the World Health Organization held its seventh meeting in Geneva, Switzerland from 5 to 7 March 2015. This article provides a summary of the discussions, conclusions and meeting recommendations. Meeting sessions included: an update on the Greater Mekong Subregion elimination strategy; an update on the RTS,S vaccine; G6PD testing to support the safe use of anti-relapse therapy for Plasmodium vivax; update from the Vector Control Advisory Group; newly proposed evidence reviews or consultations on malaria terminology, malaria in pregnancy, and the feasibility of eradication; as well as updates from the World Health Organization Global Malaria Programme regarding their strategy update and policy setting processes. Policy statements, position statements, and guidelines that arise from the Malaria Policy Advisory Committee meeting conclusions and recommendations will be formally issued and disseminated to World Health Organization Member States by the World Health Organization Global Malaria Programme.

  11. Telecommunication Policy

    DEFF Research Database (Denmark)

    Khajeheian, Datis

    2016-01-01

    This article is a response to the call of the Energy and Commerce Committee for Communications Act Update, and implies that setting a regulation which may prevent the free movement of market players for proposition of new value. As It is almost impossible to understand the future requirements of ...

  12. Tablets: A Survey of Circulation Policies at Academic Libraries

    Science.gov (United States)

    Derr, Janice; Tolppanen, Bradley P.

    2015-01-01

    This article presents the results of a Web-based survey regarding the circulation of tablets in academic libraries. The survey, which was completed by 61 respondents, identifies the most common circulation policies and procedures used. These results will help other academic institutions develop their own policy or update existing ones. Areas of…

  13. State of the States, 2012: Arts Education State Policy Summary

    Science.gov (United States)

    Arts Education Partnership (NJ1), 2012

    2012-01-01

    The "State of the States 2012" summarizes state policies for arts education identified in statute or code for all 50 states and the District of Columbia. Information is based primarily on results from the AEP Arts Education State Policy Survey conducted in 2010-11, and updated in April 2012.

  14. World Energy Update

    International Nuclear Information System (INIS)

    Ferriter, JP.

    1996-01-01

    This document deals with the importance of fossil fuels in energy consumption. In the future, the increasing energy demand will still be met by fossil fuels, although the latter will be consumed mainly in newly industrializing nations and less in developed countries. This demand for fossil fuels must be met while satisfying the objectives of security of supply and environmental protection. As far as security is concerned, it requires the maintenance and improvement of emergency response capability. Energy policy options must be developed to sustain economic growth while minimising environmental degradation. Eventually, since industrializing countries are growing in importance, new forms of association should be explored between the IEA and major energy players. (TEC)

  15. Liver Transplantation Update: 2014.

    Science.gov (United States)

    Dogan, Serkan; Gurakar, Ahmet

    2015-01-01

    of organs donated after cardiac death. Herein, we briefly summarize recent advances in knowledge related to LT. We also report common causes of death after liver transplant, including the recurrence of hepatitis C virus (HCV) and its management, and coronary artery disease (CAD), including the role of the cardiac calcium score in identifying occult CAD. Dogan S, Gurakar A. Liver Transplantation Update: 2014. Euroasian J Hepato-Gastroenterol 2015;5(2):98-106.

  16. VIIP 2017 Clinical Update

    Science.gov (United States)

    Tarver, William

    2017-01-01

    INTRODUCTION: NASA's Space Medicine community knowledge regarding the "Vision Impairment Intracranial Pressure", or VIIP.has been evolving over time.. Various measures of occupational health related to this condition had to be determined and then plans/processes put into place. The most robust of these processes were inititated in 2010. This presentation will provide a clinic update of the astronaut occupational health data related to VIIP. METHODS: NASA and its international partners require its astronauts to undergo routine health measures deemed important to monitoring VIIP. The concern is that the spaceflight environment aboard ISS could cause some astronauts to have physiologic changes detrimental to either ongoing mission operations or long-term health related to the ocular system and possibly the CNS. Specific medical tests include but are not limited to brain/orbit MRI (NASA unique protocol), OCT, fundoscopy and ocular ultrasound. Measures are taken prior to spaceflight, in-flight and post-flight. Measures to be reported include incidence of disc edema, globe flattening, choroidal folds, ONSD and change in refractive error. RESULTS: 73 ISS astronauts have been evaluated at least partially for VIIP related measures. Of these individuals, approximately 1 in 7 have experienced disc edema. The prevalence of the other findings is more complicated as the medical testing has changed over time. Overall, 26 separate individuals have experienced at least one of the findings NASA has associated with VIIP Another confounding factor is most of the astronauts have prior spaceflight experience at the time of the "pre-flight" testing. DISCUSSION: In 2010 NASA and its US operating segment (USOS) partners (CSA, ESA and JAXA) began routine occupational monitoring and data collection for most VIIP related changes. Interpretation of that data is extremely challenging for several reasons. For example, the determination of disc edema is the most complete finding as we have had

  17. NASA UAS Update

    Science.gov (United States)

    Bauer, Jeffrey Ervin; Mulac, Brenda Lynn

    2010-01-01

    Last year may prove to be a pivotal year for the National Aeronautics and Space Administration (NASA) in the Unmanned Aircraft Systems (UAS) arena, especially in relation to routine UAS access to airspace as NASA accepted an invitation to join the UAS Executive Committee (UAS ExCom). The UAS ExCom is a multi-agency, Federal executive-level committee comprised of the Federal Aviation Administration (FAA), Department of Defense (DoD), Department of Homeland Security (DHS), and NASA with the goals to: 1) Coordinate and align efforts between key Federal Government agencies to achieve routine safe federal public UAS operations in the National Airspace System (NAS); 2) Coordinate and prioritize technical, procedural, regulatory, and policy solutions needed to deliver incremental capabilities; 3) Develop a plan to accommodate the larger stakeholder community at the appropriate time; and 4) Resolve conflicts between Federal Government agencies (FAA, DoD, DHS, and NASA), related to the above goals. The committee was formed in recognition of the need of UAS operated by these agencies to access to the National Airspace System (NAS) to support operational, training, development and research requirements. In order to meet that need, technical, procedural, regulatory, and policy solutions are required to deliver incremental capabilities leading to routine access. The formation of the UAS ExCom is significant in that it represents a tangible commitment by FAA senior leadership to address the UAS access challenge. While the focus of the ExCom is government owned and operated UAS, civil UAS operations are bound to benefit by the progress made in achieving routine access for government UAS. As the UAS ExCom was forming, NASA's Aeronautics Research Mission Directorate began to show renewed interest in UAS, particularly in relation to the future state of the air transportation system under the Next Generation Air Transportation System (NextGen). NASA made funding from the American

  18. Policy Innovation in Innovation Policy

    DEFF Research Database (Denmark)

    Borras, Susana

    as with national and sub-national governments in Europe, all of them introducing interesting novelties in their innovation policy. These changes refer to different aspects of policy, mainly the content of policy initiatives towards science, technology and innovation; the instruments governments are using...... to achieve their goals; and the actors in the policy system that are being mobilised in pursuing these goals. This paper deals with these policy changes, paying special attention to the novelties introduced since the early 1990s in Europe. The perspective of this paper deals mainly on the changes introduced...... at the EU level, and mentions similar trends taking place at national and sub-national levels. The questions that guide the contents here are essentially three, namely, what are the main traits of innovation policies in Europe since the 1990s and how have the EU and different national governments approached...

  19. [Preoperative fasting. An update].

    Science.gov (United States)

    Spies, C D; Breuer, J P; Gust, R; Wichmann, M; Adolph, M; Senkal, M; Kampa, U; Weissauer, W; Schleppers, A; Soreide, E; Martin, E; Kaisers, U; Falke, K J; Haas, N; Kox, W J

    2003-11-01

    In Germany the predominant standard of preoperative care for elective surgery is fasting after midnight, with the aim of reducing the risk of pulmonary aspiration. However, for the past several years the scientific evidence supporting such a practice has been challenged. Experimental and clinical studies prove a reliable gastric emptying within 2 h suggesting that, particularly for limited intake of clear fluids up to 2 h preoperatively, there would be no increased risk for the patient. In addition, the general incidence of pulmonary aspiration during general anaesthesia (before induction, during surgery and during recovery) is extremely low, has a good prognosis and is more a consequence of insufficient airway protection and/or inadequate anaesthetic depth rather than due to the patient's fasting state. Therefore, primarily to decrease perioperative discomfort for patients, several national anaesthesia societies have changed their guidelines for preoperative fasting. They recommend a more liberal policy regarding per os intake of both liquid and solid food, with consideration of certain conditions and contraindications. The following article reviews the literature and gives an overview of the scientific background on which the national guidelines are based. The intention of this review is to propose recommendations for preoperative fasting regarding clear fluids for Germany as well.

  20. Tidal energy update 2009

    Energy Technology Data Exchange (ETDEWEB)

    O Rourke, Fergal; Boyle, Fergal; Reynolds, Anthony [Department of Mechanical Engineering, Dublin Institute of Technology, Bolton Street, Dublin 1 (Ireland)

    2010-02-15

    Tidal energy has the potential to play a valuable part in a sustainable energy future. It is an extremely predictable energy source, depending only on the gravitational pull of the moon and the sun and the centrifugal forces created by the rotation of the earth-moon system. Tidal energy has been exploited on a significant scale since the construction of the La Rance tidal barrage in France in 1967. A tidal barrage utilises the potential energy of the tide and has proven to be very successful, despite opposition from environmental groups. Kinetic energy can also be harnessed from tidal currents to generate electricity and involves the use of a tidal current turbine. This is the more desired method of capturing the energy in the tides. However, tidal current turbine technology is currently not economically viable on a large scale, as it is still in an early stage of development. This paper provides an up-to-date review of the status of tidal energy technology and identifies some of the key barriers challenging the development of tidal energy. The future development of tidal current devices and tidal barrage systems is discussed as well as examining the importance of a supportive policy to assist development. (author)

  1. PACE Status Update

    Energy Technology Data Exchange (ETDEWEB)

    M., Zimring,; Hoffman, I.; Fuller, M.

    2010-08-11

    The Federal Housing Finance Agency (FHFA) regulates Fannie Mae, Freddie Mac, and the 12 Federal Home Loan Banks (the government-sponsored enterprises - GSEs). On July 6, 2010, FHFA and the Office of the Comptroller of the Currency (OCC) concluded that Property Assessed Clean Energy (PACE) programs 'present significant safety and soundness concerns' to the housing finance industry. This statement came after a year of discussions with state and federal agencies in which PACE, a novel mechanism for financing energy efficiency and renewable energy improvements, has gone from receiving support from the White House, canonization as one of Scientific American's 'World Changing Ideas' and legislative adoption in 24 states to questionable relevance, at least in the residential sector. Whether PACE resumes its expansion as an innovative tool for financing energy efficiency and clean generation depends on outcomes in each of the three branches of government - discussions on a PACE pilot phase among federal agencies, litigation in federal court, and legislation in Congress - all highly uncertain. This policy brief addresses the practical impacts of these possible outcomes on existing and emerging PACE programs across the United States and potential paths forward.

  2. Informed policies

    International Development Research Centre (IDRC) Digital Library (Canada)

    cation technology (ICT) and now. Minister of Science and Technology, was one of the architects of Mozam- bique's ICT policy in 2000 — the first in Africa. Nationwide access to these technologies is one of the pillars of the government's science and technology policy. “We don't believe in politicians, but we believe in politics.

  3. Adaptive web data extraction policies

    Directory of Open Access Journals (Sweden)

    Provetti, Alessandro

    2008-12-01

    Full Text Available Web data extraction is concerned, among other things, with routine data accessing and downloading from continuously-updated dynamic Web pages. There is a relevant trade-off between the rate at which the external Web sites are accessed and the computational burden on the accessing client. We address the problem by proposing a predictive model, typical of the Operating Systems literature, of the rate-of-update of each Web source. The presented model has been implemented into a new version of the Dynamo project: a middleware that assists in generating informative RSS feeds out of traditional HTML Web sites. To be effective, i.e., make RSS feeds be timely and informative and to be scalable, Dynamo needs a careful tuning and customization of its polling policies, which are described in detail.

  4. Nephrogenic systemic fibrosis: epidemiology update

    DEFF Research Database (Denmark)

    Marckmann, P.

    2008-01-01

    Purpose of review The aim of this article is to outline the history of nephrogenic systemic fibrosis, a new and serious disease of patients with renal failure, and to give an update on its aetiology and prevalence. Recent findings Epidemiological and histochemical studies demonstrated that gadoli......Purpose of review The aim of this article is to outline the history of nephrogenic systemic fibrosis, a new and serious disease of patients with renal failure, and to give an update on its aetiology and prevalence. Recent findings Epidemiological and histochemical studies demonstrated...

  5. Global update: Malaysia.

    Science.gov (United States)

    1993-01-01

    Malaysia produces more condoms than any other country in the world, yet it has one of the lowest per capita condom usage rates. The official number of HIV-infected persons and of persons with AIDS in Malaysia is 5140 and 72, respectively. People working in AIDS prevention efforts believe the actual number of HIV-infected people is closer to 50,000 and climbing. People working in AIDS prevention efforts believe the actual number of HIV-infected people is closer to 50,000 and climbing. Public health officials report that AIDS is spreading rapidly through Malaysia's relatively large population of IV drug users. The Ministry of Health wants to introduce comprehensive and pragmatic efforts to stem the AIDS epidemic. They include sex education in schools, ways to prevent IV drug users from sharing needles, promotion of condoms among high risk groups, and screening to monitor HIV transmission. Islamic and Catholic groups oppose these program and policy measures, however. The new director of the Ministry's AIDS prevention unit announced during a meeting of health officials that a return to the teaching of Islam and adoption of Islamic values are the means to deal with AIDS. He suggested that boys and girls be separated, television be rigorously censored, and that Muslim scholars not be limited to mosques to do their teaching. The government has greatly increased the 1993 AIDS budget with all of the funds dedicated to blood screening, nongovernmental organizations (NGOs), and health education. The deputy health minister noted that the NGOs are supposed to address the more sensitive issues. The government does not allow any of the funds to directly go to condom promotion or programs for IV drug users, however.

  6. UPDATE: Applications of Research in Music Education. UPDATE Yearbook

    Science.gov (United States)

    Rowman & Littlefield Education, 2005

    2005-01-01

    The Fall 2004 and Spring 2005 issues of "UPDATE: Applications of Research in Music Education," in one print volume, presents hard facts and statistical data in a style that can be easily understood and appreciated by music researchers, teachers, graduates, and undergraduates alike. Includes advice to first-year music teachers, instrument…

  7. 76 FR 26235 - EPAAR Clause for Compliance with EPA Policies for Information Resources Management

    Science.gov (United States)

    2011-05-06

    ... Protection Agency (EPA) amends the EPA Acquisition Regulation (EPAAR) to update policy, procedures, and... under this contract in accordance with the IRM policies, standards, and procedures set forth on the... Agency's IRM policies, standards, and procedures. (c) Section 508 Requirements. Contract deliverables are...

  8. Shaping the Educational Policy Field: "Cross-Field Effects" in the Chinese Context

    Science.gov (United States)

    Yu, Hui

    2018-01-01

    This paper theorises how politics, economy and migrant population policies influence educational policy, utilising Bourdieusian theoretical resources to analyse the Chinese context. It develops the work of Lingard and Rawolle on cross-field effects and produces an updated three-step analytical framework. Taking the policy issue of the schooling of…

  9. 77 FR 9964 - Availability of the Reclamation National Environmental Policy Act Handbook

    Science.gov (United States)

    2012-02-21

    ... Bureau of Reclamation Availability of the Reclamation National Environmental Policy Act Handbook AGENCY... announcing the availability of its updated National Environmental Policy Act (NEPA) Handbook. This handbook... for existing laws, regulations, policies, and other guidance. It is a guidance document, and as such...

  10. Policy stories

    DEFF Research Database (Denmark)

    Ren, Carina Bregnholm; Rasmussen, Rasmus Kjærgaard

    planning and execution and of event outcomes beyond the narrow confines of bed nights and legacies. Second, we introduce policies as an entry point to unlock discussions and manifestations of value and futures which connect to AWG. In order to exemplify the workings of the AWG event in these domains, we...... present three central policy stories from the field. The stories tell of how the event was first interested, then activated and finally evaluated. Besides adding a new understanding to policy-driven events as a locus of value creation, we also argue that the AWG 2016 offer speculative bets for new...

  11. The update of the accounting procedures in Agricultural Cooperatives.

    Directory of Open Access Journals (Sweden)

    Rafael Enrique Viña Echevarría

    2014-06-01

    Full Text Available As part of the implementation of Internal Control in Agricultural Cooperatives from the standards established by the General Controller of the Republic, and the harmonization of accounting procedures Cuban Accounting Standards, It is need to update the accounting procedure manuals to guide and regulate the flows, times and registration basis, considering the current legislation, being these the purpose of the discussion in this investigation. The results focused on organizational dynamics of cooperatives, serving the agricultural cooperative sector and its relation to internal control and accounting management guidelines based on economic and social policy of the Party and the Revolution, as well as updating the procedure manuals. It even showed limitations in the application of internal control procedures and accounting according to the current regulations in Cuba, expressing the need to continue its development.

  12. Treatment of spasticity: an update

    OpenAIRE

    TEIVE, HÉLIO A.G.; ZONTA, MARISE; KUMAGAI, YUMI

    1998-01-01

    Apresentamos revisão sobre o tratamento atual da espasticidade, enfocando a terapêutica farmacológica, fisioterápica e através da utilização de toxina botulínica.We present an update about the treatment of spasticity, stressing the pharmacological treatment, physical therapy and botulinum toxin therapy.

  13. Treatability study sample exemption: update

    International Nuclear Information System (INIS)

    1997-01-01

    This document is a RCRA Information Brief intended to update the information in the 1991 Small-Scale Treatability Study Information Brief, and to address questions about the waste and treatability study sample exemptions that have arisen since References 3 and 5 were published

  14. Internet Journal of Medical Update

    African Journals Online (AJOL)

    Arun Kumar Agnihotri

    The two surveys on 'Gambling Addiction' published in this issue of the Internet Journal of. Medical Update recommend that there is a need to improve training of psychiatrists in India as regards identification, assessment and treatment of gambling addicts. I think the findings will inform the development and implementation of ...

  15. Financial Sector Assessment Update : Uganda

    OpenAIRE

    World Bank

    2005-01-01

    A joint International Monetary Fund-World Bank team conducted an assessment update of Uganda's financial system in connection with the Financial Sector Assessment Program (FSAP) in November, 2004. The purpose of the mission was to help the Ugandan authorities identify financial system strengths and weaknesses with a view to implementing an action plan to increase the system's contribution ...

  16. Upgrade trigger: Biannual performance update

    CERN Document Server

    Aaij, Roel; Couturier, Ben; Esen, Sevda; De Cian, Michel; De Vries, Jacco Andreas; Dziurda, Agnieszka; Fitzpatrick, Conor; Fontana, Marianna; Grillo, Lucia; Hasse, Christoph; Jones, Christopher Rob; Le Gac, Renaud; Matev, Rosen; Neufeld, Niko; Nikodem, Thomas; Polci, Francesco; Del Buono, Luigi; Quagliani, Renato; Schwemmer, Rainer; Seyfert, Paul; Stahl, Sascha; Szumlak, Tomasz; Vesterinen, Mika Anton; Wanczyk, Joanna; Williams, Mark Richard James; Yin, Hang; Zacharjasz, Emilia Anna

    2017-01-01

    This document presents the performance of the LHCb Upgrade trigger reconstruction sequence, incorporating changes to the underlying reconstruction algorithms and detector description since the Trigger and Online Upgrade TDR. An updated extrapolation is presented using the most recent example of an Event Filter Farm node.

  17. AMDIS and CHART update. 1

    Energy Technology Data Exchange (ETDEWEB)

    Murakami, I.; Kato, T. [National Inst. for Fusion Science, Toki, Gifu (Japan); Igarashi, A. [Miyazaki Univ., Miyazaki (JP)] [and others

    2002-10-01

    A working group for updating atomic and molecular collision data in the NIFS database AMDIS (electron scattering) and CHART (ion scattering) has been organized. This group has searched and reviewed literatures for collecting relevant atomic data with are to be included into the database. This is a summary report of the activities of this working group. (author)

  18. National Educators' Workshop: Update 1996

    Science.gov (United States)

    Gardner, James E.; Freeman, Ginger L.; Jacobs, James; Parkin, Don M.

    1997-01-01

    This document contains a collection of experiments presented and demonstrated at the National Educators' Workshop: Update 96, held at Los Alamos National Laboratory, Los Alamos, New Mexico on October 27-30, 1996. The experiments related to the nature and properties of engineering materials and provided information to assist in teaching about materials in the education community.

  19. Update of CERN exchange network

    CERN Multimedia

    2003-01-01

    An update of the CERN exchange network will be done next April. Disturbances or even interruptions of telephony services may occur from 4th to 24th April during evenings from 18:30 to 00:00 but will not exceed more than 4 consecutive hours (see tentative planning below). In addition, the voice messaging system will be shut down on March, 26th April from 18:00 to 00:00. Calls supposed to be routed to the voice messaging system will not be possible during the shutdown. CERN divisions are invited to avoid any change requests (set-ups, move or removals) of telephones and fax machines from 4th to 25th April. Everything will be done to minimize potential inconveniences which may occur during this update. There will be no loss of telephone functionalities. CERN GSM portable phones won't be affected by this change. Should you need more details, please send us your questions by email to Standard.Telephone@cern.ch. Date Change type Affected areas April 8 Update of switch in LHC 7 LHC 7 Point April 9 Update of...

  20. Update of CERN exchange network

    CERN Multimedia

    2003-01-01

    An update of the CERN exchange network will be done next April. Disturbances or even interruptions of telephony services may occur from 4th to 24th April during evenings from 18:30 to 00:00 but will not exceed more than 4 consecutive hours (see tentative planning below). In addition, the voice messaging system will be shut down on March, 26th April from 18:00 to 00:00. Calls supposed to be routed to the voice messaging system will not be possible during the shutdown. CERN divisions are invited to avoid any change requests (set-ups, move or removals) of telephones and fax machines from 4th to 25th April. Everything will be done to minimize potential inconveniences which may occur during this update. There will be no loss of telephone functionalities. CERN GSM portable phones won't be affected by this change. Should you need more details, please send us your questions by email to Standard.Telephone@cern.ch. DateChange typeAffected areas March 26Update of the voice messaging systemAll CERN sites April 4Updat...

  1. Wind turbine reliability database update.

    Energy Technology Data Exchange (ETDEWEB)

    Peters, Valerie A.; Hill, Roger Ray; Stinebaugh, Jennifer A.; Veers, Paul S.

    2009-03-01

    This report documents the status of the Sandia National Laboratories' Wind Plant Reliability Database. Included in this report are updates on the form and contents of the Database, which stems from a fivestep process of data partnerships, data definition and transfer, data formatting and normalization, analysis, and reporting. Selected observations are also reported.

  2. Nephrogenic systemic fibrosis: epidemiology update

    DEFF Research Database (Denmark)

    Marckmann, P.

    2008-01-01

    Purpose of review The aim of this article is to outline the history of nephrogenic systemic fibrosis, a new and serious disease of patients with renal failure, and to give an update on its aetiology and prevalence. Recent findings Epidemiological and histochemical studies demonstrated that gadoli...

  3. Model validation: Correlation for updating

    Indian Academy of Sciences (India)

    Department of Mechanical Engineering, Imperial College of Science, ... If we are unable to obtain a satisfactory degree of correlation between the initial theoretical model and the test data, then it is extremely unlikely that any form of model updating (correcting the model to match the test data) will succeed. Thus, a successful ...

  4. Myopic control of stochastic inventories with intermittent updates: continuous versus periodic replenishment

    OpenAIRE

    M Shnaiderman

    2012-01-01

    A manufacturer who is responsible for supplying a retailer with a single product is considered. The retailer sells the product in response to stochastic demand and provides the manufacturer with periodic updates about his inventories. Replenishing the retailer's inventory under two myopic base-stock policies is addressed. These policies, referred to as vendor managed inventory, represent a relatively new approach to allocating responsibility in the replenishment process. Specifically, the man...

  5. Archives: Internet Journal of Medical Update - EJOURNAL

    African Journals Online (AJOL)

    Items 1 - 23 of 23 ... Archives: Internet Journal of Medical Update - EJOURNAL. Journal Home > Archives: Internet Journal of Medical Update - EJOURNAL. Log in or Register to get access to full text downloads.

  6. Breast Cancer and Estrogen-Alone Update

    Science.gov (United States)

    ... Current Issue Past Issues Research News From NIH Breast Cancer and Estrogen-Alone Update Past Issues / Summer 2006 ... hormone therapy does not increase the risk of breast cancer in postmenopausal women, according to an updated analysis ...

  7. Program Updates - San Antonio River Basin

    Science.gov (United States)

    This page will house updates for this urban waters partnership location. As projects progress, status updates can be posted here to reflect the ongoing work by partners in San Antonio working on the San Antonio River Basin.

  8. Energy policies of IEA countries. 1993 review

    International Nuclear Information System (INIS)

    1994-01-01

    Energy policies in Member countries's and the international energy situation are highlighted in this 1993 edition. It reviews recent trends and developments in energy demand, conservation and efficiency, supply of primary fuels, environment, technology and R and D. This year's Review also gives an overview of significant developments in key policy areas since the IEA's creation, on the occasion of its 20th anniversary. Member countries' energy policies are reviewed in depth on a four-year cycle. In-depth reviews of the energy policies of Austria, Denmark, Germany, Greece, the United Kingdom and the United States were conducted in 1993. Energy policy developments and supply and demand trends for the other 17 countries are updated from the previous in-depth reviews and summarized in this volume. (authors). figs., tabs

  9. 75 FR 81037 - Waste Confidence Decision Update

    Science.gov (United States)

    2010-12-23

    ... NUCLEAR REGULATORY COMMISSION 10 CFR Part 51 [NRC-2008-0482] Waste Confidence Decision Update AGENCY: Nuclear Regulatory Commission. ACTION: Update and final revision of Waste Confidence Decision. SUMMARY: The U.S. Nuclear Regulatory Commission (NRC or Commission) is updating its Waste Confidence...

  10. France's Climate Plan - update 2011

    International Nuclear Information System (INIS)

    Kosciusko-Morizet, Nathalie

    2011-07-01

    After a presentation of the background of the French climate policy and of prospective data regarding carbon emissions by 2020 (global evolution, sector-based analysis, vigilance items, scenario by 2030), this report presents the different policies and measures implemented in France. After the transverse policies and measures, it presents the current status and policies and measures for different sectors: housing and office building, transports, industry, agriculture and forest, energy (energy demand and management of greenhouse gas emissions related to energy production), wastes, public authorities and local communities

  11. 76 FR 7848 - Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation...

    Science.gov (United States)

    2011-02-11

    ... Corporation has been appointed receiver for purposes of the statement of policy published in the July 2, 1992... CORPORATION Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation Has Been Appointed Either Receiver, Liquidator, or Manager AGENCY: Federal Deposit Insurance Corporation...

  12. 78 FR 29134 - Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation...

    Science.gov (United States)

    2013-05-17

    ... Corporation has been appointed receiver for purposes of the statement of policy published in the July 2, 1992... CORPORATION Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation Has Been Appointed Either Receiver, Liquidator, or Manager AGENCY: Federal Deposit Insurance Corporation...

  13. 78 FR 6105 - Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation...

    Science.gov (United States)

    2013-01-29

    ... Corporation has been appointed receiver for purposes of the statement of policy published in the July 2, 1992... CORPORATION Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation Has Been Appointed Either Receiver, Liquidator, or Manager AGENCY: Federal Deposit Insurance Corporation...

  14. 78 FR 50054 - Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation...

    Science.gov (United States)

    2013-08-16

    ... Corporation has been appointed receiver for purposes of the statement of policy published in the July 2, 1992... CORPORATION Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation Has Been Appointed Either Receiver, Liquidator, or Manager AGENCY: Federal Deposit Insurance Corporation...

  15. 78 FR 12754 - Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation...

    Science.gov (United States)

    2013-02-25

    ... Corporation has been appointed receiver for purposes of the statement of policy published in the July 2, 1992... CORPORATION Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation Has Been Appointed Either Receiver, Liquidator, or Manager AGENCY: Federal Deposit Insurance Corporation...

  16. 77 FR 9924 - Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation...

    Science.gov (United States)

    2012-02-21

    ... Corporation has been appointed receiver for purposes of the statement of policy published in the July 2, 1992... CORPORATION Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation Has Been Appointed Either Receiver, Liquidator, or Manager AGENCY: Federal Deposit Insurance Corporation...

  17. 77 FR 5802 - Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation...

    Science.gov (United States)

    2012-02-06

    ... Corporation has been appointed receiver for purposes of the statement of policy published in the July 2, 1992... CORPORATION Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation Has Been Appointed Either Receiver, Liquidator, or Manager AGENCY: Federal Deposit Insurance Corporation...

  18. 77 FR 37673 - Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation...

    Science.gov (United States)

    2012-06-22

    ... Corporation has been appointed receiver for purposes of the statement of policy published in the July 2, 1992... CORPORATION Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation Has Been Appointed Either Receiver, Liquidator, or Manager AGENCY: Federal Deposit Insurance Corporation...

  19. 78 FR 25083 - Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation...

    Science.gov (United States)

    2013-04-29

    ... Corporation has been appointed receiver for purposes of the statement of policy published in the July 2, 1992... CORPORATION Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation has been Appointed Either Receiver, Liquidator, or Manager AGENCY: Federal Deposit Insurance Corporation...

  20. 78 FR 58304 - Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation...

    Science.gov (United States)

    2013-09-23

    ... Corporation has been appointed receiver for purposes of the statement of policy published in the July 2, 1992... CORPORATION Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation Has Been Appointed Either Receiver, Liquidator, or Manager AGENCY: Federal Deposit Insurance Corporation...

  1. 77 FR 47841 - Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation...

    Science.gov (United States)

    2012-08-10

    ... Corporation has been appointed receiver for purposes of the statement of policy published in the July 2, 1992... CORPORATION Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation Has Been Appointed Either Receiver, Liquidator, or Manager AGENCY: Federal Deposit Insurance Corporation...

  2. 75 FR 6667 - Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation...

    Science.gov (United States)

    2010-02-10

    ... Corporation has been appointed receiver for purposes of the statement of policy published in the July 2, 1992... CORPORATION Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation Has Been Appointed Either Receiver, Liquidator, or Manager AGENCY: Federal Deposit Insurance Corporation...

  3. 78 FR 48679 - Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation...

    Science.gov (United States)

    2013-08-09

    ... Corporation has been appointed receiver for purposes of the statement of policy published in the July 2, 1992... CORPORATION Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation has been Appointed Either Receiver, Liquidator, or Manager AGENCY: Federal Deposit Insurance Corporation...

  4. 77 FR 70438 - Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation...

    Science.gov (United States)

    2012-11-26

    ... Corporation has been appointed receiver for purposes of the statement of policy published in the July 2, 1992... CORPORATION Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation Has Been Appointed Either Receiver, Liquidator, or Manager AGENCY: Federal Deposit Insurance Corporation...

  5. 78 FR 53759 - Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation...

    Science.gov (United States)

    2013-08-30

    ... Corporation has been appointed receiver for purposes of the statement of policy published in the July 2, 1992... CORPORATION Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation Has Been Appointed Either Receiver, Liquidator, or Manager AGENCY: Federal Deposit Insurance Corporation...

  6. 77 FR 4321 - Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation...

    Science.gov (United States)

    2012-01-27

    ... Corporation has been appointed receiver for purposes of the statement of policy published in the July 2, 1992... CORPORATION Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation Has Been Appointed Either Receiver, Liquidator, or Manager AGENCY: Federal Deposit Insurance Corporation...

  7. 77 FR 65686 - Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation...

    Science.gov (United States)

    2012-10-30

    ... Corporation has been appointed receiver for purposes of the statement of policy published in the July 2, 1992... CORPORATION Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation Has Been Appointed Either Receiver, Liquidator, or Manager AGENCY: Federal Deposit Insurance Corporation...

  8. 77 FR 66840 - Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation...

    Science.gov (United States)

    2012-11-07

    ... Corporation has been appointed receiver for purposes of the statement of policy published in the July 2, 1992... CORPORATION Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation Has Been Appointed Either Receiver, Liquidator, or Manager AGENCY: Federal Deposit Insurance Corporation...

  9. 78 FR 77127 - Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation...

    Science.gov (United States)

    2013-12-20

    ... Corporation has been appointed receiver for purposes of the statement of policy published in the July 2, 1992... CORPORATION Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation Has Been Appointed Either Receiver, Liquidator, or Manager AGENCY: Federal Deposit Insurance Corporation...

  10. 77 FR 41405 - Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation...

    Science.gov (United States)

    2012-07-13

    ... Corporation has been appointed receiver for purposes of the statement of policy published in the July 2, 1992... CORPORATION Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation Has Been Appointed Either Receiver, Liquidator, or Manager AGENCY: Federal Deposit Insurance Corporation...

  11. 77 FR 60988 - Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation...

    Science.gov (United States)

    2012-10-05

    ... Corporation has been appointed receiver for purposes of the statement of policy published in the July 2, 1992... CORPORATION Update to Notice of Financial Institutions for Which the Federal Deposit Insurance Corporation has been Appointed Either Receiver, Liquidator, or Manager AGENCY: Federal Deposit Insurance Corporation...

  12. Computer Science in High School Graduation Requirements. ECS Education Trends (Updated)

    Science.gov (United States)

    Zinth, Jennifer

    2016-01-01

    Allowing high school students to fulfill a math or science high school graduation requirement via a computer science credit may encourage more student to pursue computer science coursework. This Education Trends report is an update to the original report released in April 2015 and explores state policies that allow or require districts to apply…

  13. 75 FR 61419 - Inquiry on Copyright Policy, Creativity, and Innovation in the Internet Economy

    Science.gov (United States)

    2010-10-05

    ... infringement is the primary motivation for the Task Force to seek an updated understanding of stakeholders..., NTIA has been a lead contributor to the development of Internet policy in the Executive branch and...

  14. Environmental Development Plan for Transportation Energy Conservation. FY 79 update

    Energy Technology Data Exchange (ETDEWEB)

    Singh, M. K.; Bernard, III, M. J.

    1978-12-15

    This is the first annual update of the Environment Development Plan (EDP) for the DOE Division of Transportation Energy Conservation program. It identifies the ecosystem, resource, physical environment, health, safety, and socioeconomic concerns associated with the division's transportation programs. These programs include the research, development, demonstration and assessment (RDD and A) of seventeen transportation technologies and several strategy and policy development and implementation projects. The transportation technologies projects deal with highway transport including electric vehicles, marine transport and pipeline transport. This EDP presents a research and assessment plan for resolving any potentially adverse environmental concerns stemming from these programs.

  15. [Preoperative fasting guidelines: an update].

    Science.gov (United States)

    López Muñoz, A C; Busto Aguirreurreta, N; Tomás Braulio, J

    2015-03-01

    Anesthesiology societies have issued various guidelines on preoperative fasting since 1990, not only to decrease the incidence of lung aspiration and anesthetic morbidity, but also to increase patient comfort prior to anesthesia. Some of these societies have been updating their guidelines, as such that, since 2010, we now have 2 evidence-based preoperative fasting guidelines available. In this article, an attempt is made to review these updated guidelines, as well as the current instructions for more controversial patients such as infants, the obese, and a particular type of ophthalmic surgery. Copyright © 2014 Sociedad Española de Anestesiología, Reanimación y Terapéutica del Dolor. Publicado por Elsevier España, S.L.U. All rights reserved.

  16. Updating Recursive XML Views of Relations

    DEFF Research Database (Denmark)

    Choi, Byron; Cong, Gao; Fan, Wenfei

    2009-01-01

    This paper investigates the view update problem for XML views published from relational data. We consider XML views defined in terms of mappings directed by possibly recursive DTDs compressed into DAGs and stored in relations. We provide new techniques to efficiently support XML view updates...... specified in terms of XPath expressions with recursion and complex filters. The interaction between XPath recursion and DAG compression of XML views makes the analysis of the XML view update problem rather intriguing. Furthermore, many issues are still open even for relational view updates, and need...... to be explored. In response to these, on the XML side, we revise the notion of side effects and update semantics based on the semantics of XML views, and present effecient algorithms to translate XML updates to relational view updates. On the relational side, we propose a mild condition on SPJ views, and show...

  17. Cannabis and Psychopathology : Update 2004

    OpenAIRE

    Grover, Sandeep; Basu, Debasish

    2004-01-01

    The study of cannabis use and psychopathology remains an interesting area from both academic and pragmatic perspectives. This article provides an update on the progress made in this area over the past decade or so. Psychopathology and psychiatric syndromes associated with cannabis use that have received research attention in recent years include cannabis withdrawal, cannabis and psychotic disorders (especially schizophrenia), depression, anxiety, and cognitive impairment. Status of a specific...

  18. CSTT Update: Fuel Quality Analyzer

    Energy Technology Data Exchange (ETDEWEB)

    Brosha, Eric L. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Lujan, Roger W. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Mukundan, Rangachary [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Rockward, Tommy [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Romero, Christopher J. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Williams, Stefan [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Wilson, Mahlon S. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2018-02-06

    These are slides from a presentation. The following topics are covered: project background (scope and approach), developing the prototype (timeline), update on intellectual property, analyzer comparisons (improving humidification, stabilizing the baseline, applying clean-up strategy, impact of ionomer content and improving clean-up), proposed operating mode, considerations for testing in real-world conditions (Gen 1 analyzer electronics development, testing partner identified, field trial planning), summary, and future work.

  19. Profile updating for information systems

    International Nuclear Information System (INIS)

    Abrantes, J.F.

    1983-02-01

    Profiles updating methods were analysed. A method suitable to the characteristics of the system used in the research (SDI/CIN/CNEN) that uses as the selection criterio the threshold and weights criterion, was determined. Relevance weighting theory was described and experiments to verify precision were carried out. The improvements obtained were good nevertheless more significant tests are required to attain more reliable results. (Author) [pt

  20. Towards Dynamic Updates In AUTOSAR

    OpenAIRE

    Martorell , Hélène; Fabre , Jean-Charles; Roy , Matthieu; Valentin , Régis

    2013-01-01

    International audience; Vehicles are nowadays increasingly software-intensive.Current practice shows that the whole software system is tested, validated and then uploaded in ECUs in a monolithic fashion, before a vehicle is put in operation. Yet, adding speci c features or updates without restarting the full validation and upload procedure could yield to signi cant gains. Unfortunately, the AUTOSAR (AUTomotive Open System ARchitec- ture) standard does not include native support for software u...

  1. Atypical odontalgia--an update.

    Science.gov (United States)

    Patel, Seena B; Boros, Audrey L; Kumar, Satish K S

    2012-09-01

    Atypical odontalgia is a commonly misdiagnosed condition that frequently leads to unnecessary dental treatments such as extraction and endodontic therapy. These treatments often worsen the pain. Despite greater recognition and understanding of this condition, proper diagnosis and treatment remains a challenge. It is believed that atypical odontalgia is a neuropathic condition. This article updates the current understanding of the etiology and pathophysiology of atypical odontalgia, and provides appropriate diagnostic and management approaches for this condition.

  2. Update on Internet2 Activities

    Science.gov (United States)

    Yun, T. Charles

    [14 Feb 2003] I propose an overview talk/update on several Internet2 activities that might be of interest to the e-VLBI community including: End-to-End performance project (PiPES); national (American) fiber infrastructure (a.k.a. National Light Rail, FiberCo, etc.); request for interest in short-term, dedicated, test-labmdas (inside the US only at this point).

  3. Reference projection energy and emissions. 2012 Update. Energy and emissions for the years 2012, 2020 and 2030

    International Nuclear Information System (INIS)

    Verdonk, M.; Wetzels, W.

    2012-08-01

    This report contains estimates of greenhouse gas emissions and air pollutants and the use of renewable energy for the year 2020. An outlook is presented for the year 2030. This estimate is an update of the Reference Projection Energy and Emissions 2010-2020, published in 2010. The goal of the update is to provide insight into the progress in realizing the targets for Dutch policies with regard to climate, air and energy. [nl

  4. Update of CERN exchange network

    CERN Multimedia

    2003-01-01

    An update of the CERN exchange network will be done next April. Disturbances or even interruptions of telephony services may occur from 4th to 24th April during evenings from 18:30 to 00:00 but will not exceed more than 4 consecutive hours (see tentative planning below). In addition, the voice messaging system will be shut down on March, 26th April from 18:00 to 00:00. Calls supposed to be routed to the voice messaging system will not be possible during the shutdown. CERN divisions are invited to avoid any change requests (set-ups, move or removals) of telephones and fax machines from 4th to 25th April. Everything will be done to minimize potential inconveniences which may occur during this update. There will be no loss of telephone functionalities. CERN GSM portable phones won't be affected by this change. Should you need more details, please send us your questions by email to Standard.Telephone@cern.ch. Date Change type Affected areas March 26 Update of the voice messaging system All CERN sites April...

  5. Policy Reader

    International Nuclear Information System (INIS)

    1985-09-01

    This policy reader comprises: Correspondence; Memorandum of Understanding between the US Department of Transportation and the US Department of Energy for the Transportation of Radioactive Materials under the Nuclear Waste Policy Act; Internal Guidelines for Interactions with Communities and Local Governments; Statement by Ben C. Rusche before the Committee on Interior and Insular Affairs, Subcommittee on Energy and the Environment, US House of Representatives, September 13, 1985; Speech presented by Ben C. Rusche before the ANS/CNS/AESJ/ENS Topical Meeting, Pasco, Washington, September 24, 1985 - ''Status of the United States' High-Level Nuclear Waste Disposal Program''; and ''DOE Seeks Comments on Nuclear Transportation Planning,'' DOE News, September 30, 1985

  6. Population policy.

    Science.gov (United States)

    1987-03-01

    Participants in the Seminar on Population Policies for Top-level Policy Makers and Program Managers, meeting in Thailand during January 1987, examined the challenges now facing them regarding the implementation of fertility regulation programs in their respective countries -- Bangladesh, China, India, Indonesia, Malaysia, Nepal, Pakistan, the Philippines, the Republic of Korea, and Thailand. This Seminar was organized to coincide with the completion of an Economic and Social Commission for Asia and the Pacific (ESCAP) study investigating the impact and efficiency of family planning programs in the region. Country studies were reviewed at the Seminar along with policy issues about the status of women, incentive and disincentive programs, and socioeconomic factors affecting fertility. In Bangladesh the government recognizes population growth as its top priority problem related to the socioeconomic development of the country and is working to promote a reorientation strategy from the previous clinic-oriented to a multidimensional family welfare program. China's family planning program seeks to postpone marraige, space the births of children between 3-5 years, and promote the 1-child family. Its goal is to reduce the rate of natural increase from 12/1000 in 1978 to 5/1000 by 1985 and 0 by 2000. India's 7th Five-Year-Plan (1986-90) calls for establishing a 2-child family norm by 2000. In Indonesia the government's population policy includes reducing the rate of population growth, achieving a redistribution of the population, adjusting economic factors, and creating prosperous families. The government of Indonesia reversed its policy to reduce the population growth rate in 1984 and announced its goal of achieving a population of 70 million by 2100 in order to support mass consumption industries. It has created an income tax deduction system favoring large families and maternity benefits for women who have up to 5 children as incentives. Nepal's official policy is to

  7. Language Policy

    DEFF Research Database (Denmark)

    Lauridsen, Karen M.

    2008-01-01

    Like any other text, instructive texts function within a given cultural and situational setting and may only be available in one language. However, the end users may not be familiar with that language and therefore unable to read and understand the instructions. This article therefore argues...... that instructive texts should always be available in a language that is understood by the end users, and that a corporate communication policy which includes a language policy should ensure that this is in fact the case for all instructive texts....

  8. «Soft Power»: the Updated Theoretical Concept and Russian Assembly Model

    Directory of Open Access Journals (Sweden)

    Владимир Сергеевич Изотов

    2011-12-01

    Full Text Available The article is dedicated to critically important informational and ideological aspects of Russia's foreign policy. The goal is to revise and specify the notion soft power in the context of rapidly changing space of global politics. During the last years international isolation of Russia, including informational and ideological sphere is increasing. The way to overcome this negative trend is modernization of foreign policy strategy on the basis of updating of operational tools and ideological accents. It's becoming obvious that the real foreign policy success in the global world system is achieved by the use of soft power. The author tries to specify and conceptualize the phenomenon of Russia's soft power as a purposeful external ideology facing the urgent need of updating.

  9. Internet policy and economics challenges and perspectives

    CERN Document Server

    Pupillo, Lorenzo

    2009-01-01

    Presents cutting-edge research, practice, and policy in electronic communications, commerce, and cultureIncludes contributions from leading researchers and industry expertsAddresses such hot-button issues as privacy issues, universal access, cybercrime, intellectual property rights, on-line content, and peer-to-peer networksApplies perspectives from economics, political science, law, business, and communicationsFully updated and revised paperback edition will appeal to practitioners, policymakers, and students

  10. Country policy profile - Cyprus. December 2015

    International Nuclear Information System (INIS)

    2015-12-01

    In 2013, four renewable energy sources (RES) support schemes were implemented in Cyprus: grants and/or subsidies for the use of renewable energy sources and energy saving, regulation on cost of ancillary services and the use of system. Moreover, support is available for investments for the improvement of competitiveness and management of farm waste (RES-Legal Europe, 2014). This report monitors the policy changes after the release of the Cypriot 2013 Progress Report and is has been updated until December 2015

  11. Country policy profile - Cyprus. August 2015

    International Nuclear Information System (INIS)

    2015-08-01

    In 2013, four renewable energy sources (RES) support schemes were implemented in Cyprus: grants and/or subsidies for the use of renewable energy sources and energy saving, regulation on cost of ancillary services and the use of system. Moreover, support is available for investments for the improvement of competitiveness and management of farm waste (RES-Legal Europe, 2014). This report monitors the policy changes after the release of the Cypriotic 2013 Progress Report and is regularly updated

  12. The Energy Imperative: Report Update

    National Research Council Canada - National Science Library

    Marburger, III, John H; Kvamme, E. F

    2008-01-01

    .... energy security over the next two decades. Overall, since publication of the 2006 report, PCAST has seen notable improvements in energy supply and demand trends, advanced energy technologies, and Federal policies related to energy security...

  13. A New Zealand Market Update

    International Nuclear Information System (INIS)

    Frazer, S.

    2006-02-01

    Since the first Climate Change and Business Conference in November 2004, New Zealand's climate change policies have been through an extraordinary period. This paper provides background on New Zealand's Kyoto Protocol obligations, and the challenge of its unusual greenhouse gas emissions profile. Progress on policy measures is summarised with a focus on the market activities, Kyoto compliant and grey market, that have resulted. The latter section covers the inventory reassessment leading to a full review of New Zealand's climate change policies. This review ultimately led to the scrapping of the carbon tax and the need to develop new policies. The paper ends with a forecast on the impacts of these changes on the potential for a New Zealand emission trading system and New Zealand's business and government engagement in international market trades

  14. Group Policy Fundamentals, Security, and the Managed Desktop

    CERN Document Server

    Moskowitz, Jeremy

    2010-01-01

    The ultimate Group Policy guide-now updated for Windows 7 and Server 2008 R2!. IT and network administrators can streamline their Windows Server management tasks by using Group Policy tools to automate or implement rules, processes, or new security across the enterprise. In this comprehensive guide, Microsoft Group Policy MVP Jeremy Moskowitz thoroughly explores Group Policy across all Windows platforms, including the latest on Windows 7 and Server 2008 R2. If you're a Windows network administrator managing scores of users and computers, you need this essential reference on your desk.: Covers

  15. Energy policy of the Czech Republic

    Energy Technology Data Exchange (ETDEWEB)

    Cerny, M. [Ministry of Industry and Trade, Prague (Czechoslovakia)

    1995-12-01

    On February 16, 1992, the Government of the Czech Republic sanctioned, by its Decree No. 112/82, its first Energy Policy. Since that time, a number of conditions have changed: first of all, there was the partition of the former Federal Czechoslovak Republic, then the privatization of most of energy producing corporations, the deregulation of a significant proportion of power and energy commodities, the decision to bring to an end the construction of the Temelin nuclear power station, the creation of conditions for the construction of the Ingoldstadt oil pipeline, etc. These steps, on which the final decisions have been made, have brought about the necessity of updating the existing general Energy Policy. The updated Energy Policy is based on the Programme Statement by the Government of the Czech Republic of July 1992, as well as on other materials associated with energy and power generation, either approved or negotiated by the Government, in particular the State Environmental Policy the Rules of the State Raw Materials Policy, the European Association Agreement, the European Energy Charter, the results of the Uruguayan Round of GATT, the Convention on Climate Changes, the Ecological Action Programme for central and East-European countries, and other international documents that have either been, or are likely to be sanctioned by the Czech Government (especially the European Energy Charter Treaty, and the protocol on Trans-boundary Air Pollution and on Further Reduction of Sulphur Oxide Emissions).

  16. Nordic MCL2 trial update

    DEFF Research Database (Denmark)

    Geisler, Christian H; Kolstad, Arne; Laurell, Anna

    2012-01-01

    Mantle cell lymphoma (MCL) is a heterogenic non-Hodgkin lymphoma entity, with a median survival of about 5 years. In 2008 we reported the early - based on the median observation time of 4 years - results of the Nordic Lymphoma Group MCL2 study of frontline intensive induction immunochemotherapy...... and autologous stem cell transplantation (ASCT), with more than 60% event-free survival at 5 years, and no subsequent relapses reported. Here we present an update after a median observation time of 6·5 years. The overall results are still excellent, with median overall survival and response duration longer than...

  17. Update in Infectious Diseases 2017.

    Science.gov (United States)

    Candel, F J; Peñuelas, M; Lejárraga, C; Emilov, T; Rico, C; Díaz, I; Lázaro, C; Viñuela-Prieto, J M; Matesanz, M

    2017-09-01

    Antimicrobial resistance in complex models of continuous infection is a current issue. The update 2017 course addresses about microbiological, epidemiological and clinical aspects useful for a current approach to infectious disease. During the last year, nosocomial pneumonia approach guides, recommendations for management of yeast and filamentous fungal infections, review papers on the empirical approach to peritonitis and extensive guidelines on stewardship have been published. HIV infection is being treated before and more intensively. The implementation of molecular biology, spectrometry and inmunology to traditional techniques of staining and culture achieve a better and faster microbiological diagnosis. Finally, the infection is increasingly integrated, assessing non-antibiotic aspects in the treatment.

  18. Big bang nucleosynthesis: An update

    Energy Technology Data Exchange (ETDEWEB)

    Olive, Keith A. [William I. Fine Theoretical Physics Institute, School of Physics and Astronomy, University of Minnesota, Minneapolis, MN 55455 (United States)

    2013-07-23

    An update on the standard model of big bang nucleosynthesis (BBN) is presented. With the value of the baryon-tophoton ratio determined to high precision by WMAP, standard BBN is a parameter-free theory. In this context, the theoretical prediction for the abundances of D, {sup 4}He, and {sup 7}Li is discussed and compared to their observational determination. While concordance for D and {sup 4}He is satisfactory, the prediction for {sup 7}Li exceeds the observational determination by a factor of about four. Possible solutions to this problem are discussed.

  19. Primary Anorectal Melanoma: An Update

    Directory of Open Access Journals (Sweden)

    P Carcoforo, M.T Raiji, G.M Palini, M Pedriali, U Maestroni, G Soliani, A Detroia, M.V Zanzi, A.L Manna, J.G Crompton, R.C Langan, A Stojadinovic, I Avital

    2012-01-01

    Full Text Available The anorectum is a rare anatomic location for primary melanoma. Mucosal melanoma is a distinct biological and clinical entity from the more common cutaneous melanoma. It portrays worse prognosis than cutaneous melanoma, with distant metastases being the overwhelming cause of morbidity and mortality. Surgery is the treatment of choice, but significant controversy exists over the extent of surgical resection. We present an update on the state of the art of anorectal mucosal melanoma. To illustrate the multimodality approach to anorectal melanoma, we present a typical patient.

  20. Communication technology update and fundamentals

    CERN Document Server

    Grant, August E

    2014-01-01

    A classic now in its 14th edition, Communication Technology Update and Fundamentals is the single best resource for students and professionals looking to brush up on how these technologies have developed, grown, and converged, as well as what's in store for the future. It begins by developing the communication technology framework-the history, ecosystem, and structure-then delves into each type of technology, including everything from mass media, to computers and consumer electronics, to networking technologies. Each chapter is written by faculty and industry experts who p

  1. Cushing syndrome: update on testing.

    Science.gov (United States)

    Raff, Hershel

    2015-03-01

    Endogenous hypercortisolism (Cushing syndrome) is one of the most enigmatic diseases in clinical medicine. The diagnosis and differential diagnosis of Cushing syndrome depend on proper laboratory evaluation. In this review, an update is provided on selected critical issues in the diagnosis and differential diagnosis of Cushing syndrome: the use of late-night salivary cortisol in initial diagnosis and for postoperative surveillance, and the use of prolactin measurement to improve the performance of inferior petrosal sinus sampling to distinguish Cushing disease from ectopic adrenocorticotropic hormone (ACTH) syndrome during differential diagnosis of ACTH-dependent Cushing syndrome. Copyright © 2015 Elsevier Inc. All rights reserved.

  2. Neurobiology of emotions: an update.

    Science.gov (United States)

    Esperidião-Antonio, Vanderson; Majeski-Colombo, Marilia; Toledo-Monteverde, Diana; Moraes-Martins, Glaciele; Fernandes, Juliana José; Bauchiglioni de Assis, Marjorie; Montenegro, Stefânia; Siqueira-Batista, Rodrigo

    2017-06-01

    The 'nature' of emotions is one of the archaic themes of Western thought, thematized in different cultural manifestations - such as art, science, philosophy, myths and religion -, since Ancient times. In the last decades, the advances in neurosciences have permitted the construction of hypotheses that explain emotions, especially through the studies involving the limbic system. To present an updated discussion about the neurobiology of processes relating to emotions - focusing (1) on the main neural structures that relate to emotions, (2) the paths and circuits of greater relevance, (3) the implicated neurotransmitters, (4) the connections that possess neurovegetative control and (5) the discussion about the main emotions - is the objective of this present article.

  3. Los Alamos Climatology 2016 Update

    Energy Technology Data Exchange (ETDEWEB)

    Bruggeman, David Alan [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-02-10

    The Los Alamos National Laboratory (LANL or the Laboratory) operates a meteorology monitoring network to support LANL emergency response, engineering designs, environmental compliance, environmental assessments, safety evaluations, weather forecasting, environmental monitoring, research programs, and environmental restoration. Weather data has been collected in Los Alamos since 1910. Bowen (1990) provided climate statistics (temperature and precipitation) for the 1961– 1990 averaging period, and included other analyses (e.g., wind and relative humidity) based on the available station locations and time periods. This report provides an update to the 1990 publication Los Alamos Climatology (Bowen 1990).

  4. Antibiotic policy

    OpenAIRE

    Gyssens, Inge

    2011-01-01

    There is a clear association between antibiotic use and resistance both on individual and population levels. In the European Union, countries with large antibiotic consumption have higher resistance rates. Antibiotic resistance leads to failed treatments, prolonged hospitalisations, increased costs and deaths. With few new antibiotics in the Research & Development pipeline, prudent antibiotic use is the only option to delay the development of resistance. Antibiotic policy consists of prescrib...

  5. The updated billion-ton resource assessment

    Science.gov (United States)

    Anthony Turhollow; Robert Perlack; Laurence Eaton; Matthew Langholtz; Craig Brandt; Mark Downing; Lynn Wright; Kenneth Skog; Chad Hellwinckel; Bryce Stokes; Patricia Lebow

    2014-01-01

    This paper summarizes the results of an update to a resource assessment, published in 2005, commonly referred to as the Billion-Ton Study (BTS). The updated results are consistent with the 2005 BTS in terms of overall magnitude. The 2005 BTS projected between 860 and 1240 Tg of biomass available in the 2050 timeframe, while the Billion-Ton Update (BT2), for a price of...

  6. Renewables global status report - 2006 Update

    International Nuclear Information System (INIS)

    Martinot, Eric; Mastny, Lisa; Rosbotham, Lyle; Suding, Paul; Lempp, Philippe

    2006-01-01

    This update covers major changes since mid-2005 when the Renewables 2005 Global Status Report was written. Background and further information is contained in the original report, available at www.ren21.net. Record investment in new renewable energy capacity occurred in 2005-$38 billion, up from $30 billion in 2004. Germany and China were the investment leaders, with about $7 billion each, followed by the United States, Spain, Japan, and India.Wind power registered the second highest added capacity, almost as much as large hydropower, with existing capacity growing 24 percent to reach 59 gigawatts (GW). Biomass power production saw 50-100 percent increases in annual production in several countries in 2004. High growth rates also occurred in bio-diesel (85 percent increase in annual production) and grid-connected solar PV (55 percent increase in existing capacity). Solar hot water existing capacity grew by 23 percent in China and reached record levels across Europe as well. And construction began in the United States and Spain on the world's first utility-scale solar thermal power plants in 20 years. Country leadership changed or broadened in several areas. Germany leapt ahead of Japan in grid-connected solar PV, adding 600 megawatts (MW) in one year to achieve a higher cumulative capacity. The United States was the leader in wind power additions for the first time since 1992, while at the same time India's existing capacity surpassed wind pioneer Denmark. Ten countries added over 300 MW of wind, up from five countries that did so in 2004. India passed Japan in total renewable power capacity. In ethanol, U.S. production caught up to Brazil, long the world's leading producer, and three new European Union (EU) countries became producers. In bio-diesel, nine new EU countries became producers. The renewables industry captured investors' attention, as the number of renewable energy companies or divisions with market valuations greater than $40 million

  7. Scientific Integrity Policy Creation and Implementation.

    Science.gov (United States)

    Koizumi, K.

    2017-12-01

    Ensuring the integrity of science was a priority for the Obama Administration. In March 2009, President Obama issued a Presidential Memorandum that recognized the need for the public to be able to trust the science and scientific process informing public policy decisions. In 2010, the White House Office of Science and Technology Policy (OSTP) issued a Memorandum providing guidelines for Federal departments and agencies to follow in developing scientific integrity policies. This Memorandum describes minimum standards for: (1) strengthening the foundations of scientific integrity in government, including by shielding scientific data and analysis from inappropriate political influence; (2) improving public communication about science and technology by promoting openness and transparency; (3) enhancing the ability of Federal Advisory Committees to provide independent scientific advice; and (4) supporting the professional development of government scientists and engineers. The Memorandum called upon the heads of departments and agencies to develop scientific integrity policies that meet these requirements. At the end of the Obama Administration, 24 Federal departments and agencies had developed and implemented scientific integrity policies consistent with the OSTP guidelines. This year, there are significant questions as to the Trump Administration's commitment to these scientific integrity policies and interest in the Congress in codifying these policies in law. The session will provide an update on the status of agency scientific integrity policies and legislation.

  8. Internet Policy

    Science.gov (United States)

    Lehr, William H.; Pupillo, Lorenzo Maria

    The Internet is now widely regarded as essential infrastructure for our global economy and society. It is in our homes and businesses. We use it to communicate and socialize, for research, and as a platform for E-commerce. In the late 1990s, much was predicted about what the Internet has become at present; but now, we have actual experience living with the Internet as a critical component of our everyday lives. Although the Internet has already had profound effects, there is much we have yet to realize. The present volume represents a third installment in a collaborative effort to highlight the all-encompassing, multidisciplinary implications of the Internet for public policy. The first installment was conceived in 1998, when we initiated plans to organize an international conference among academic, industry, and government officials to discuss the growing policy agenda posed by the Internet. The conference was hosted by the European Commission in Brussels in 1999 and brought together a diverse mix of perspectives on what the pressing policy issues would be confronting the Internet. All of the concerns identified remain with us today, including how to address the Digital Divide, how to modify intellectual property laws to accommodate the new realities of the Internet, what to do about Internet governance and name-space management, and how to evolve broadcast and telecommunications regulatory frameworks for a converged world.

  9. Model Updating Nonlinear System Identification Toolbox Project

    Data.gov (United States)

    National Aeronautics and Space Administration — ZONA Technology (ZONA) proposes to develop an enhanced model updating nonlinear system identification (MUNSID) methodology that utilizes flight data with...

  10. Changing the policy for intermittent preventive treatment with sulfadoxine-pyrimethamine during pregnancy in Malawi.

    Science.gov (United States)

    Mwendera, Chikondi A; de Jager, Christiaan; Longwe, Herbert; Phiri, Kamija; Hongoro, Charles; Mutero, Clifford M

    2017-02-20

    The growing resistance of Plasmodium falciparum to sulfadoxine-pyrimethamine (SP) treatment for uncomplicated malaria led to a recommendation by the World Health Organization for the use of artemisinin-based combination therapy. Inevitably, concerns were also raised surrounding the use of SP for intermittent prevention treatment of malaria during pregnancy (IPTp) amidst the lack of alternative drugs. Malawi was the first country to adopt intermittent prevention treatment with SP in 1993, and updated in 2013. This case study examines the policy updating process and the contribution of research and key stakeholders to this process. The findings support the development of a malaria research-to-policy framework in Malawi. Documents and evidence published from 1993 to 2012 were systematically reviewed in addition to key informant interviews. The online search identified 170 potential publications, of which eight from Malawi met the inclusion criteria. Two published studies from Malawi were instrumental in the WHO policy recommendation which in turn led to the updating of national policies. The updated policy indicates that more than two SP doses, as informed by research, overcome the challenges of the first policy of two SP doses only because of ineffectiveness by P. falciparum resistance and the global lack of replacement drugs to SP for IPTp. International WHO recommendations facilitated a smooth policy change driven by motivated local leadership with technical and financial support from development partners. Policy development and implementation should include key stakeholders and use local malaria research in a research-to-policy framework.

  11. Alternative energies. Updates on progress

    International Nuclear Information System (INIS)

    Ferreira, German

    2013-01-01

    Presents fundamental and applied research of alternative energies. Address key pillars in the alternative energy field, such as: biomass energy, hydrogen energy, solar energy, wind energy, hydroelectric power, geothermal energy and their environmental implications, with the most updated progress. Includes the life cycle assessment and thermoeconomic analysis as tools for evaluating and optimising environmental and cost subjects. This book presents nine chapters based on fundamental and applied research of alternative energies. At the present time, the challenge is that technology has to come up with solutions that can provide environmentally friendly energy supply options that are able to cover the current world energy demand. Experts around the world are working on these issues for providing new solutions that will break the existing technological barriers. This book aims to address key pillars in the alternative energy field, such as: biomass energy, hydrogen energy, solar energy, wind energy, hydroelectric power, geothermal energy and their environmental implications, with the most updated progress for each pillar. It also includes the life cycle assessment (LCA) and thermoeconomic analysis (TA) as tools for evaluating and optimising environmental and cost subjects. Chapters are organized into fundamental research, applied research and future trends; and written for engineers, academic researches and scientists.

  12. Alternative energies. Updates on progress

    Energy Technology Data Exchange (ETDEWEB)

    Ferreira, German (ed.) [CIRCE - Centre of Research for Energy Resources and Consumption, Zaragoza (Spain)

    2013-07-01

    Presents fundamental and applied research of alternative energies. Address key pillars in the alternative energy field, such as: biomass energy, hydrogen energy, solar energy, wind energy, hydroelectric power, geothermal energy and their environmental implications, with the most updated progress. Includes the life cycle assessment and thermoeconomic analysis as tools for evaluating and optimising environmental and cost subjects. This book presents nine chapters based on fundamental and applied research of alternative energies. At the present time, the challenge is that technology has to come up with solutions that can provide environmentally friendly energy supply options that are able to cover the current world energy demand. Experts around the world are working on these issues for providing new solutions that will break the existing technological barriers. This book aims to address key pillars in the alternative energy field, such as: biomass energy, hydrogen energy, solar energy, wind energy, hydroelectric power, geothermal energy and their environmental implications, with the most updated progress for each pillar. It also includes the life cycle assessment (LCA) and thermoeconomic analysis (TA) as tools for evaluating and optimising environmental and cost subjects. Chapters are organized into fundamental research, applied research and future trends; and written for engineers, academic researches and scientists.

  13. Renewables global status report - 2009 Update

    International Nuclear Information System (INIS)

    Sawin, Janet L.; Martinot, Eric; Mastny, Lisa; Lempp, Philippe; Sonntag-O'Brien, Virginia; Lempp, Philippe; Foulon, Samia; Roussell, Jodie; Welker, Bettina

    2009-01-01

    from conventional sources (including gas, coal, oil, and nuclear). Renewable energy industries boomed during most of 2008. Global solar PV production increased by 90 percent to 6.9 GW in 2008. China usurped Japan to become the new world leader in PV cell production and also experienced huge growth in its wind power industry, with many new companies producing wind turbines and components. Globally, the wind industry continued to push turbine sizes higher, with models of 3 MW or larger becoming more widespread. The concentrating solar power (CSP) industry saw many entrants and new manufacturing facilities. The ethanol and bio-diesel industries similarly expanded, particularly in North America and Latin America, and the cellulosic ethanol industry was in the process of booming, with 300 million liters per year of capacity under construction. Although the clean energy sector initially weathered the financial crisis in late 2008 better than many other sectors, renewable investment did experience a downturn after September 2008. However, projects continued to progress and many economic stimulus bills included components for supporting renewable energy. At the same time, development assistance for renewables in developing countries expanded greatly, reaching about $2 billion in 2008. By early 2009, policy targets existed in at least 73 countries, and at least 64 countries had policies to promote renewable power generation, including 45 countries and 18 states/provinces/territories with feed-in tariffs (many of these recently updated). The number of countries/states/ provinces with renewable portfolio standards increased to 49. Policy targets for renewable energy were added, supplemented, revised, or clarified in a large number of countries in 2008. Many forms of policy support for renewables were added, supplemented, or extended in a number of countries during 2008. For example, new solar PV subsidy programs were adopted in Australia, China, Japan, Luxembourg, the Netherlands

  14. "See Translation": Explicit and Implicit Language Policies on Facebook

    Science.gov (United States)

    Hendus, Ulrike

    2015-01-01

    The currently tested "See Translation" button can be considered an expression of Facebook's explicit language policy. It offers the users fast and easy translations of others' status updates and can therefore be seen as diminishing language barriers and reducing the need for a lingua franca in polylingual networks, thus enhancing…

  15. Foreign Assistance Policies of India and China | IDRC - International ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    While the aid policies of these countries have garnered attention, there is, as yet, little understanding of their systems and strategies. This study addresses this gap by updating data on each country's foreign assistance and mapping the institutions involved, the beneficiaries, the sectors they are investing in, and their funding ...

  16. Non-Linear Approximation of Bayesian Update

    KAUST Repository

    Litvinenko, Alexander

    2016-06-23

    We develop a non-linear approximation of expensive Bayesian formula. This non-linear approximation is applied directly to Polynomial Chaos Coefficients. In this way, we avoid Monte Carlo sampling and sampling error. We can show that the famous Kalman Update formula is a particular case of this update.

  17. Census in Schools Educator Update, March 2009

    Science.gov (United States)

    US Census Bureau, 2009

    2009-01-01

    The "Census in Schools Educator Update" is sent to educators and educational organizations periodically to keep them informed about current and upcoming census data and to provide ideas about how to use data in the classroom. This issue of the "Census in Schools Educator Update" newsletter focuses on the following topics: (1)…

  18. Better Plants Progress Update Fall 2013

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2013-09-23

    This Progress Update summarizes the significant energy saving achievements and cumulative cost savings made by these industry leaders from 2010-2012. The update also shares the plans and priorities over the next year for the Better Plants Program to continue to advance energy efficiency in the industrial sector.

  19. 34 CFR 668.55 - Updating information.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false Updating information. 668.55 Section 668.55 Education... Information § 668.55 Updating information. (a)(1) Unless the provisions of paragraph (a)(2) or (a)(3) of this... applicant to verify the information contained in his or her application for assistance in an award year if...

  20. Control of Interference during Working Memory Updating

    Science.gov (United States)

    Szmalec, Arnaud; Verbruggen, Frederick; Vandierendonck, Andre; Kemps, Eva

    2011-01-01

    The current study examined the nature of the processes underlying working memory updating. In 4 experiments using the n-back paradigm, the authors demonstrate that continuous updating of items in working memory prevents strong binding of those items to their contexts in working memory, and hence leads to an increased susceptibility to proactive…

  1. Brief update on endometriosis treatment

    Directory of Open Access Journals (Sweden)

    Moamar Al-Jefout

    2011-09-01

    Full Text Available Endometriosis is a chronic debilitating disease with features of chronic inflammation. Endometriosis is defined as the presence of endometrial like stroma and glands outside the uterine cavity (1. Medical professionals dealing with endometriosis face a lot of problems; in diagnosis, treatment and follow up of patients. Recent advances in molecular and clinical sciences offered a wide range of modalities for treatment. However, up to date there is no single very successful option for the ultimate treatment. In this review I have searched the literature using Medline, Pubmed, text books and other search engines to look for the most updated modalities for the treatment of endometriosis both surgical and medical ones. It seems to be that for fertility purposes surgical treatment followed by ART is the best available most beneficial way of dealing with endometriosis, while medical treatment is the best way to treat pain symptoms associated with endometriosis.

  2. Update on abusive head trauma.

    Science.gov (United States)

    Shaahinfar, Ashkon; Whitelaw, Kevin D; Mansour, Karim M

    2015-06-01

    This article provides an update on abusive head trauma (AHT), focusing on new developments most salient to the emergency medicine clinician, including epidemiology, clinical recognition, diagnostic work-up, management of neurologic injury, and public health implications. The recent literature has focused on honing the clinician's ability to recognize AHT and its immediate sequelae, to more accurately distinguish between abusive and accidental head injuries by patterns of neuroimaging and retinal hemorrhages, and to appreciate the long-term impacts. Specifically, both a clinical prediction rule and biomarker show promise, and new research advocates for the early identification of subclinical seizures as well as cervical spine injuries. The emergency medicine provider must be able to recognize and manage children who may have AHT and to appreciate when the diagnostic findings warrant consultation with a child protection team. These authors summarize the recent and notable advances in our understanding of AHT.

  3. Methodological update in Medicina Intensiva.

    Science.gov (United States)

    García Garmendia, J L

    2018-04-01

    Research in the critically ill is complex by the heterogeneity of patients, the difficulties to achieve representative sample sizes and the number of variables simultaneously involved. However, the quantity and quality of records is high as well as the relevance of the variables used, such as survival. The methodological tools have evolved to offering new perspectives and analysis models that allow extracting relevant information from the data that accompanies the critically ill patient. The need for training in methodology and interpretation of results is an important challenge for the intensivists who wish to be updated on the research developments and clinical advances in Intensive Medicine. Copyright © 2017 Elsevier España, S.L.U. y SEMNIM. All rights reserved.

  4. [An update on myasthenia gravis].

    Science.gov (United States)

    Martínez Torre, S; Gómez Molinero, I; Martínez Girón, R

    2018-03-16

    Myasthenia gravis is one of the most common disorders that affect neuromuscular transmission. It is currently one of the most understood and characterised autoimmune disorders Its typical symptoms are fluctuating weakness and fatigue that affects a combination of ocular muscles, bulbar functions, as well as limb and respiratory muscles, which are due to an immune attack against the postsynaptic membrane of the neuromuscular junction. The diagnosis of myasthenia gravis is based on clinical and serological test. It is a disease that can be effectively controlled with the current therapeutic lines, even achieving a complete remission. An update of this interesting disorder is now presented. Copyright © 2018 Sociedad Española de Médicos de Atención Primaria (SEMERGEN). Publicado por Elsevier España, S.L.U. All rights reserved.

  5. Papillomaviruses in ruminants: An update.

    Science.gov (United States)

    Daudt, C; Da Silva, F R C; Lunardi, M; Alves, C B D T; Weber, M N; Cibulski, S P; Alfieri, A F; Alfieri, A A; Canal, C W

    2018-03-30

    Papillomaviruses (PVs) are complex viruses which infect the skin or mucosae of a broad range of amniotes worldwide. They cause benign or malignant lesions depending on environmental factors, virus oncogenicity and the location of infection. Bovine papillomaviruses (BPVs) are the second most studied PVs beyond human PVs. In the past few years, genetic characterization of animal PVs has increased due to the availability of new techniques, which simplified the sequencing of entire genomes. Therefore, this review aims to provide an update of the current epidemiology, classification and genome features of ruminant PVs (mainly BPVs) affecting animals worldwide. The review also aimed to clarify the key differences between the high-risk Delta papillomaviruses and the seemingly low-risk Xi, Epsilon, Dyoxi and Dyokappapillomavirus as well as the recently described PVs BPV18, 19, 21 and PpuPV1 that belongs to an unclassified genus. © 2018 Blackwell Verlag GmbH.

  6. TWEAT '95: User's documentation update

    International Nuclear Information System (INIS)

    Robertus, B.; Lambert, R.

    1996-03-01

    This report is designed to be a supplement to TWEAT'94 (PVTD-C94-05.01K Rev.1). It is intended to describe the primary features of the Ternary Waste Envelope Assessment Tool software package that have been added in FY'95 and how to use them. It contains only minimal duplication of information found in TWEAT'94 even though all features of TWEAT'94 will still be available. Emphasis on this Update is the binary plotting capability and the OWL Import modifications. Like it's predecessors, this manual does not provide instructions for modifying the program code itself. The user of TWEAT'95 is expected to be familiar with the basic concepts and operation of the TWEAT software as discussed in TWEAT'94. Software and hardware requirements have not changed since TWEAT'94. TWEAT has now been tested using Macintosh System software versions 6.05 through 7.5

  7. Sprucing up the site - update

    CERN Multimedia

    2009-01-01

    As mentioned in a previous article the Bulletin will be publishing regular short updates following the consolidation work going on around the CERN sites: All internal lighting is being replaced in the office buildings on the Prevessin site. Work has started in building 866 and will move to 864 and 865 later. New energy-efficient lights are being installed, which will reduce electricity consumption by 30 -50%, and in the common areas like corridors the lighting will be switched on by motion sensors. Also in the Prevessin site, the lines in the car parks are being repainted. This will continue in the Meyrin site later. Work has started in Building 30 to completely refurbish the AT Auditorium.

  8. 2009 State Policies on Assessment Participation and Accommodations for Students with Disabilities. Synthesis Report 83

    Science.gov (United States)

    Christensen, Laurene L.; Braam, Maureen; Scullin, Sarah; Thurlow, Martha L.

    2011-01-01

    The National Center on Educational Outcomes (NCEO) has been tracking and analyzing state policies on assessment participation and accommodations since 1992. The purpose of the current analysis is to update information on these policies that was last reported by NCEO in 2008 (based on 2007 data). In addition, current state accommodations policies…

  9. 2005 State Policies on Assessment Participation and Accommodations for Students with Disabilities. Synthesis Report 64

    Science.gov (United States)

    Lazarus, Sheryl S.; Thurlow, Martha L.; Lail, Kathryn E.; Eisenbraun, Kristin D.; Kato, Kentaro

    2006-01-01

    The National Center on Educational Outcomes (NCEO) has been tracking and analyzing state policies on assessment participation and accommodations since 1992. The purpose of the current analysis is to update information on these policies that was last reported by NCEO in 2005 (based on 2003 data). The current analysis of states' 2005 participation…

  10. Ask These Key Questions When You Review Child Abuse Reporting Policies.

    Science.gov (United States)

    Rogers, Joy J.

    1988-01-01

    Urges policymakers to examine and update their school system's child abuse reporting policy. Such policies must be adequate to help endangered children, protect their right to privacy, and avoid overprotection. Advises on ways to protect staff against unnecessary accusations and develop inservice training programs discussing child abuse, state…

  11. Fiscal policy under alternative monetary policy regimes

    OpenAIRE

    Diaz-Roldan; Carmelo Monteagudo-Cuerva

    2013-01-01

    In the particular policy framework of a monetary union, the management of fiscal policy becomes an issue of special relevance, because the fiscal discipline imposed by the monetary agreements could limit the scope of stabilization fiscal policies, and its implications on economic growth. Therefore, is not trivial to manage fiscal policy in such particular economic framework. In this paper we will review the implications of fiscal policy in open economies. But we will pay special attention to ...

  12. Family Economic Security Policies and Child and Family Health

    Science.gov (United States)

    Spencer, Rachael A.; Komro, Kelli A.

    2017-01-01

    In this review we examine the effects of family economic security policies (i.e., minimum wage, Earned Income Tax Credit, unemployment insurance, Temporary Assistance to Needy Families) on child and family health outcomes, summarize policy generosity across states in the U.S., and discuss directions and possibilities for future research. This manuscript is an update to a review article that was published in 2014. Millions of Americans are affected by family economic security policies each year, many of whom are the most vulnerable in society. There is increasing evidence that these policies impact health outcomes and behaviors of adults and children. Further, research indicates that, overall, policies which are more restrictive are associated with poorer health behaviors and outcomes; however, the strength of the evidence differs across each of the four policies. There is significant diversity in state-level policies and it is plausible that these policy variations are contributing to health disparities across and within states. Despite increasing evidence of the relationship between economic policies and health, there continues to be limited attention to this issue. State policy variations offer a valuable opportunity for scientists to conduct natural experiments and contribute to evidence linking social policy effects to family and child wellbeing. The mounting evidence will help to guide future research and policy making for evolving toward a more nurturing society for family and child health and wellbeing. PMID:28176020

  13. Family Economic Security Policies and Child and Family Health.

    Science.gov (United States)

    Spencer, Rachael A; Komro, Kelli A

    2017-03-01

    In this review, we examine the effects of family economic security policies (i.e., minimum wage, earned income tax credit, unemployment insurance, Temporary Assistance to Needy Families) on child and family health outcomes, summarize policy generosity across states in the USA, and discuss directions and possibilities for future research. This manuscript is an update to a review article that was published in 2014. Millions of Americans are affected by family economic security policies each year, many of whom are the most vulnerable in society. There is increasing evidence that these policies impact health outcomes and behaviors of adults and children. Further, research indicates that, overall, policies which are more restrictive are associated with poorer health behaviors and outcomes; however, the strength of the evidence differs across each of the four policies. There is significant diversity in state-level policies, and it is plausible that these policy variations are contributing to health disparities across and within states. Despite increasing evidence of the relationship between economic policies and health, there continues to be limited attention to this issue. State policy variations offer a valuable opportunity for scientists to conduct natural experiments and contribute to evidence linking social policy effects to family and child well-being. The mounting evidence will help to guide future research and policy making for evolving toward a more nurturing society for family and child health and well-being.

  14. Country policy profile - Romania. April 2015

    International Nuclear Information System (INIS)

    2015-04-01

    According to the Directive 2009/28/EC of the European Parliament and of the European Council on the promotion of the use of energy from renewable sources the target for the share of energy from renewable sources in gross final energy consumption in the year 2020 for Romania is 24%, whereas in 2012 it reached 21,3%. The Romanian renewable electricity promotion relies primarily on a quota system. Grid operators are obliged to develop their grids on the request of a plant operator, if the connection of a plant to the grid requires so. Romania has certain policies pertaining to renewable energy like training programmes for RES installers and on enhancing the development of RES-H infrastructure. This report monitors the policy changes after the release of the 2013 Progress Report for Romania and is regularly updated. In recent months, no significant change in country's RES policies has been reported

  15. Country policy profile - Romania. December 2015

    International Nuclear Information System (INIS)

    2015-12-01

    According to the Directive 2009/28/EC of the European Parliament and of the European Council on the promotion of the use of energy from renewable sources the target for the share of energy from renewable sources in gross final energy consumption in the year 2020 for Romania is 24%, whereas in 2012 it reached 21,3%. The Romanian renewable electricity promotion relies primarily on a quota system. Grid operators are obliged to develop their grids on the request of a plant operator, if the connection of a plant to the grid requires so. Romania has certain policies pertaining to renewable energy like training programmes for RES installers and on enhancing the development of RES-H infrastructure. This report monitors the policy changes after the release of the 2013 Progress Report for Romania and is regularly updated. In recent months, no significant change in country's RES policies has been reported

  16. Planetary Protection and Mars Special Regions--A Suggestion for Updating the Definition.

    Science.gov (United States)

    Rettberg, Petra; Anesio, Alexandre M; Baker, Victor R; Baross, John A; Cady, Sherry L; Detsis, Emmanouil; Foreman, Christine M; Hauber, Ernst; Ori, Gian Gabriele; Pearce, David A; Renno, Nilton O; Ruvkun, Gary; Sattler, Birgit; Saunders, Mark P; Smith, David H; Wagner, Dirk; Westall, Frances

    2016-02-01

    We highlight the role of COSPAR and the scientific community in defining and updating the framework of planetary protection. Specifically, we focus on Mars "Special Regions," areas where strict planetary protection measures have to be applied before a spacecraft can explore them, given the existence of environmental conditions that may be conducive to terrestrial microbial growth. We outline the history of the concept of Special Regions and inform on recent developments regarding the COSPAR policy, namely, the MEPAG SR-SAG2 review and the Academies and ESF joint committee report on Mars Special Regions. We present some new issues that necessitate the update of the current policy and provide suggestions for new definitions of Special Regions. We conclude with the current major scientific questions that remain unanswered regarding Mars Special Regions.

  17. The Impact of Implementing Tobacco Control Policies: The 2017 Tobacco Control Policy Scorecard.

    Science.gov (United States)

    Levy, David T; Tam, Jamie; Kuo, Charlene; Fong, Geoffrey T; Chaloupka, Frank

    2018-01-17

    The Tobacco Control Scorecard, published in 2004, presented estimates of the effectiveness of different policies on smoking rates. Since its publication, new evidence has emerged. We update the Scorecard to include recent studies of demand-reducing tobacco policies for high-income countries. We include cigarette taxes, smoke-free air laws, media campaigns, comprehensive tobacco control programs, marketing bans, health warnings, and cessation treatment policies. To update the 2004 Scorecard, a narrative review was conducted on reviews and studies published after 2000, with additional focus on 3 policies in which previous evidence was limited: tobacco control programs, graphic health warnings, and marketing bans. We consider evaluation studies that measured the effects of policies on smoking behaviors. Based on these findings, we derive estimates of short-term and long-term policy effect sizes. Cigarette taxes, smoke-free air laws, marketing restrictions, and comprehensive tobacco control programs are each found to play important roles in reducing smoking prevalence. Cessation treatment policies and graphic health warnings also reduce smoking and, when combined with policies that increase quit attempts, can improve quit success. The effect sizes are broadly consistent with those previously reported for the 2004 Scorecard but now reflect the larger evidence base evaluating the impact of health warnings and advertising restrictions.This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

  18. 77 FR 66483 - Public Comment on the Draft Federal Urban Design Element and the Draft Update to the Federal...

    Science.gov (United States)

    2012-11-05

    ... COMMISSION Public Comment on the Draft Federal Urban Design Element and the Draft Update to the Federal... Urban Design Element provides policies that will guide the design and management of federal buildings... resources. All interested parties are invited to submit written comment. The draft Federal Urban Design...

  19. Utility residual fuel oil market conditions: An update

    International Nuclear Information System (INIS)

    Mueller, H.A. Jr.

    1992-01-01

    Planning for residual fuel oil usage and management remains an important part of the generation fuel planning and management function for many utilities. EPRI's Utility Planning Methods Center has maintained its analytical overview of the fuel oil markets as part of its overall fuel planning and management research program. This overview provides an update of recent fuel oil market directions. Several key events of the past year have had important implications for residual fuel oil markets. The key events have been the changes brought about by the Persian Gulf War and its aftermath, as well as continuing environmental policy developments. The Persian Gulf conflict has created renewed interest in reducing fuel oil use by utilities as part of an overall reduction in oil imports. The policy analysis performed to date has generally failed to properly evaluate utility industry capability. The Persian Gulf conflict has also resulted in an important change in the structure of international oil markets. The result of this policy-based change is likely to be a shift in oil pricing strategy. Finally, continued change in environmental requirements is continuing to shift utility residual oil requirements, but is also changing the nature of the US resid market itself

  20. Dataset of statements on policy integration of selected intergovernmental organizations

    Directory of Open Access Journals (Sweden)

    Jale Tosun

    2018-04-01

    Full Text Available This article describes data for 78 intergovernmental organizations (IGOs working on topics related to energy governance, environmental protection, and the economy. The number of IGOs covered also includes organizations active in other sectors. The point of departure for data construction was the Correlates of War dataset, from which we selected this sample of IGOs. We updated and expanded the empirical information on the IGOs selected by manual coding. Most importantly, we collected the primary law texts of the individual IGOs in order to code whether they commit themselves to environmental policy integration (EPI, climate policy integration (CPI and/or energy policy integration (EnPI.

  1. Dataset of statements on policy integration of selected intergovernmental organizations.

    Science.gov (United States)

    Tosun, Jale; Peters, B Guy

    2018-04-01

    This article describes data for 78 intergovernmental organizations (IGOs) working on topics related to energy governance, environmental protection, and the economy. The number of IGOs covered also includes organizations active in other sectors. The point of departure for data construction was the Correlates of War dataset, from which we selected this sample of IGOs. We updated and expanded the empirical information on the IGOs selected by manual coding. Most importantly, we collected the primary law texts of the individual IGOs in order to code whether they commit themselves to environmental policy integration (EPI), climate policy integration (CPI) and/or energy policy integration (EnPI).

  2. Impact of EU agricultural policy on developing countries

    DEFF Research Database (Denmark)

    Boysen, Ole; Jensen, Hans Grinsted; Matthews, Alan

    2016-01-01

    Despite substantial reforms, the EU’s Common Agricultural Policy (CAP) is still criticised for its detrimental effects on developing countries. This paper provides updated evidence on the impact of the CAP on one developing country, Uganda. It goes beyond estimating macro-level economic effects...... by analysing the impacts on poverty. The policy simulation results show that eliminating EU agricultural support would have marginal but nonetheless positive impacts on the Ugandan economy and its poverty indicators. From the perspective of the EU’s commitment to policy coherence for development, this supports...... the view that further reducing EU Agricultural support would be positive for development....

  3. Impact of EU agricultural policy on developing countries

    DEFF Research Database (Denmark)

    Boysen, Ole; Jensen, Hans Grinsted; Matthews, Alan

    2014-01-01

    Despite substantial reforms, the EU’s Common Agricultural Policy (CAP) is still criticised for its detrimental effects on developing countries. This paper provides updated evidence on the impact of the CAP on one developing country, Uganda. It goes beyond estimating macro-level economic effects...... by analysing the impacts on poverty. The policy simulation results show that eliminating EU agricultural support would have marginal but nonetheless positive impacts on the Ugandan economy and its poverty indicators. From the perspective of the EU’s commitment to policy coherence for development, this supports...... the view that further reducing EU Agricultural support would be positive for development....

  4. Optimizing Key Updates in Sensor Networks

    DEFF Research Database (Denmark)

    Yuksel, Ender; Nielson, Hanne Riis; Nielson, Flemming

    2011-01-01

    Sensor networks offer the advantages of simple and low–resource communication. Nevertheless, security is of particular importance in many cases such as when sensitive data is communicated or tamper-resistance is required. Updating the security keys is one of the key points in security, which...... restrict the amount of data that may be exposed when a key is compromised. In this paper, we propose novel key update methods, and benefiting from stochastic model checking we propose a novel method for determining optimal key update strategies for custom network scenarios. We also present a case study...

  5. Studying the potential impact of automated document classification on scheduling a systematic review update

    Science.gov (United States)

    2012-01-01

    Background Systematic Reviews (SRs) are an essential part of evidence-based medicine, providing support for clinical practice and policy on a wide range of medical topics. However, producing SRs is resource-intensive, and progress in the research they review leads to SRs becoming outdated, requiring updates. Although the question of how and when to update SRs has been studied, the best method for determining when to update is still unclear, necessitating further research. Methods In this work we study the potential impact of a machine learning-based automated system for providing alerts when new publications become available within an SR topic. Some of these new publications are especially important, as they report findings that are more likely to initiate a review update. To this end, we have designed a classification algorithm to identify articles that are likely to be included in an SR update, along with an annotation scheme designed to identify the most important publications in a topic area. Using an SR database containing over 70,000 articles, we annotated articles from 9 topics that had received an update during the study period. The algorithm was then evaluated in terms of the overall correct and incorrect alert rate for publications meeting the topic inclusion criteria, as well as in terms of its ability to identify important, update-motivating publications in a topic area. Results Our initial approach, based on our previous work in topic-specific SR publication classification, identifies over 70% of the most important new publications, while maintaining a low overall alert rate. Conclusions We performed an initial analysis of the opportunities and challenges in aiding the SR update planning process with an informatics-based machine learning approach. Alerts could be a useful tool in the planning, scheduling, and allocation of resources for SR updates, providing an improvement in timeliness and coverage for the large number of medical topics needing SRs

  6. Country policy profile - Poland. December 2015

    International Nuclear Information System (INIS)

    2015-12-01

    According to the Directive 2009/28/EC of the European Parliament and of the European Council on the promotion of the use of energy from renewable sources the target for the share of energy from renewable sources in gross final energy consumption in the year 2020 for Poland is 15%. Poland promotes renewable electricity through a quota system, tax relief and subsidies, as well as loans. There are three subsidy models and a loan scheme, which support heat generated from renewable energy sources. In dimension to transport renewable energy is promoted primarily by bio-fuels. The Republic of Poland established two programmes for renewable energy plants: a training programme, which is dedicated to installers in RES sector and certification system pertaining solar thermal installations. This report monitors the policy changes after the release of the 2013 Progress Report for Poland and was regularly updated (updated until December 2015)

  7. Obesity management: update on orlistat.

    Science.gov (United States)

    Drew, Belinda S; Dixon, Andrew F; Dixon, John B

    2007-01-01

    Over the past 20 years obesity has become a worldwide concern of frightening proportion. The World Health Organization estimates that there are over 400 million obese and over 1.6 billion overweight adults, a figure which is projected to almost double by 2015. This is not a disease restricted to adults - at least 20 million children under the age of 5 years were overweight in 2005 (WHO 2006). Overweight and obesity lead to serious health consequences including coronary artery disease, stroke, type-2 diabetes, heart failure, dyslipidemia, hypertension, reproductive and gastrointestinal cancers, gallstones, fatty liver disease, osteoarthritis and sleep apnea (Padwal et al 2003). Modest weight loss in the obese of between 5% and 10% of bodyweight is associated with improvements in cardiovascular risk profiles and reduced incidence of type 2 diabetes (Goldstein 1992; Avenell et al 2004; Padwal and Majumdar 2007). Orlistat, a gastric and pancreatic lipase inhibitor that reduces dietary fat absorption by approximately 30%, has been approved for use for around ten years (Zhi et al 1994; Hauptman 2000). There is now a growing body of evidence to suggest that Orlistat assists weight loss and that it may also have additional benefits. The aim of this review is to provide a brief update on the current literature studying the efficacy, safety and significance of the use of Orlistat in clinical practice.

  8. Vasectomy reversal: a clinical update

    Directory of Open Access Journals (Sweden)

    Abhishek P Patel

    2016-01-01

    Full Text Available Vasectomy is a safe and effective method of contraception used by 42-60 million men worldwide. Approximately 3%-6% of men opt for a vasectomy reversal due to the death of a child or divorce and remarriage, change in financial situation, desire for more children within the same marriage, or to alleviate the dreaded postvasectomy pain syndrome. Unlike vasectomy, vasectomy reversal is a much more technically challenging procedure that is performed only by a minority of urologists and places a larger financial strain on the patient since it is usually not covered by insurance. Interest in this procedure has increased since the operating microscope became available in the 1970s, which consequently led to improved patency and pregnancy rates following the procedure. In this clinical update, we discuss patient evaluation, variables that may influence reversal success rates, factors to consider in choosing to perform vasovasostomy versus vasoepididymostomy, and the usefulness of vasectomy reversal to alleviate postvasectomy pain syndrome. We also review the use of robotics for vasectomy reversal and other novel techniques and instrumentation that have emerged in recent years to aid in the success of this surgery.

  9. Stuttering: Clinical and research update.

    Science.gov (United States)

    Perez, Hector R; Stoeckle, James H

    2016-06-01

    To provide an update on the epidemiology, genetics, pathophysiology, diagnosis, and treatment of developmental stuttering. The MEDLINE and Cochrane databases were searched for past and recent studies on the epidemiology, genetics, pathophysiology, diagnosis, and treatment of developmental stuttering. Most recommendations are based on small studies, limited-quality evidence, or consensus. Stuttering is a speech disorder, common in persons of all ages, that affects normal fluency and time patterning of speech. Stuttering has been associated with differences in brain anatomy, functioning, and dopamine regulation thought to be due to genetic causes. Attention to making a correct diagnosis or referral in children is important because there is growing consensus that early intervention with speech therapy for children who stutter is critical. For adults, stuttering can be associated with substantial psychosocial morbidity including social anxiety and low quality of life. Pharmacologic treatment has received attention in recent years, but clinical evidence is limited. The mainstay of treatment for children and adults remains speech therapy. A growing body of research has attempted to uncover the pathophysiology of stuttering. Referral for speech therapy remains the best option for children and adults. Copyright© the College of Family Physicians of Canada.

  10. Updating neutrino magnetic moment constraints

    Directory of Open Access Journals (Sweden)

    B.C. Cañas

    2016-02-01

    Full Text Available In this paper we provide an updated analysis of the neutrino magnetic moments (NMMs, discussing both the constraints on the magnitudes of the three transition moments Λi and the role of the CP violating phases present both in the mixing matrix and in the NMM matrix. The scattering of solar neutrinos off electrons in Borexino provides the most stringent restrictions, due to its robust statistics and the low energies observed, below 1 MeV. Our new limit on the effective neutrino magnetic moment which follows from the most recent Borexino data is 3.1×10−11μB at 90% C.L. This corresponds to the individual transition magnetic moment constraints: |Λ1|≤5.6×10−11μB, |Λ2|≤4.0×10−11μB, and |Λ3|≤3.1×10−11μB (90% C.L., irrespective of any complex phase. Indeed, the incoherent admixture of neutrino mass eigenstates present in the solar flux makes Borexino insensitive to the Majorana phases present in the NMM matrix. For this reason we also provide a global analysis including the case of reactor and accelerator neutrino sources, presenting the resulting constraints for different values of the relevant CP phases. Improved reactor and accelerator neutrino experiments will be needed in order to underpin the full profile of the neutrino electromagnetic properties.

  11. The Updated Multiple Star Catalog

    Science.gov (United States)

    Tokovinin, Andrei

    2018-03-01

    The catalog of hierarchical stellar systems with three or more components is an update of the original 1997 version. For 2000 hierarchies, the new Multiple Star Catalog (MSC) provides distances, component masses and periods, and supplementary information (astrometry, photometry, identifiers, orbits, notes). The MSC content and format are explained, and its incompleteness and strong observational selection are stressed. Nevertheless, the MSC can be used for statistical studies and is a valuable source for planning observations of multiple stars. Rare classes of stellar hierarchies found in the MSC (with six or seven components, extremely eccentric orbits, planar and possibly resonant orbits, hosting planets) are briefly presented. High-order hierarchies have smaller velocity dispersion compared to triples and are often associated with moving groups. The paper concludes with an analysis of the ratio of periods and separations between inner and outer subsystems. In wide hierarchies, the ratio of semimajor axes, estimated statistically, is distributed between 3 and 300, with no evidence of dynamically unstable systems.

  12. Febrile seizures. Update and controversies.

    Science.gov (United States)

    Jan, Mohammed M; Girvin, John P

    2004-10-01

    Febrile seizures are the most common seizure disorder in children younger than 5 years of age. Most febrile seizures are brief, do not require any specific treatment or workup, and have benign prognoses. Generalists and pediatricians are frequently faced with anxious parents and are required to make rational decisions regarding the need to investigate and treat such a child. They subsequently need to provide further prognostic information and counseling to the families. The aim of this article is to provide an updated overview of febrile seizures and review the most recent diagnostic and therapeutic recommendations. Despite the progress in the understanding of this benign syndrome, a wide variation in physician evaluation and management persists. However, there is recent evidence that pediatricians are becoming more selective in admitting and investigating children with febrile seizures. Admitted children frequently had complex seizures, status epilepticus, or were ill looking. Considering the full scope of febrile seizures, the yield of investigations that might alter management remains low and does not justify extensive work-up or prolonged hospitalization.

  13. Extraglottic airway devices: technology update

    Directory of Open Access Journals (Sweden)

    Sharma B

    2017-08-01

    Full Text Available Bimla Sharma, Chand Sahai, Jayashree Sood Department of Anaesthesiology, Pain and Perioperative Medicine, Sir Ganga Ram Hospital, New Delhi, India Abstract: Extraglottic airway devices (EADs have revolutionized the field of airway management. The invention of the laryngeal mask airway was a game changer, and since then, there have been several innovations to improve the EADs in design, functionality, safety and construction material. These have ranged from changes in the shape of the mask, number of cuffs and material used, like rubber, polyvinylchloride and latex. Phthalates, which were added to the construction material in order to increase device flexibility, were later omitted when this chemical was found to have serious adverse reproductive outcomes. The various designs brought out by numerous companies manufacturing EADs resulted in the addition of several devices to the airway market. These airway devices were put to use, many of them with inadequate or no evidence base regarding their efficacy and safety. To reduce the possibility of compromising the safety of the patient, the Difficult Airway Society (DAS formed the Airway Device Evaluation Project Team (ADEPT to strengthen the evidence base for airway equipment and vet the new extraglottic devices. A preuse careful analysis of the design and structure may help in better understanding of the functionality of a particular device. In the meantime, the search for the ideal EAD continues. Keywords: extraglottic airway devices, laryngeal mask airway, other extraglottic airway devices, safety, technology update

  14. IDSA releases updated coccidioidomycosis guidelines

    Directory of Open Access Journals (Sweden)

    Robbins RA

    2016-09-01

    Full Text Available No abstract available. Article truncated at 150 words. The Infectious Diseases Society of America (IDSA has released updated Guidelines for the Treatment of Coccidioidomycosis, also known as cocci or Valley Fever (1. Coccidioidomycosis is a fungal infection endemic to the southwestern United States and a common cause of pneumonia and pulmonary nodules in this area. However, the infection can disseminate systemically especially in immunocompromised hosts and certain ethnic populations resulting in a variety of pulmonary and extrapulmonary complications. In addition to recommendations for these complications, the new guidelines address management of special at-risk populations, preemptive management strategies in at-risk populations and after unintentional laboratory exposure. The guidelines also suggest shorter courses of antibiotics for hospitalized patients and more ambulatory treatment for most individuals who have contracted Valley Fever. The panel was led by John N. Galgiani, MD, director of the Valley Fever Center for Excellence at the University of Arizona Health Sciences. Galgiani led a panel of 16 ...

  15. Updating of the bovine neosporosis

    Directory of Open Access Journals (Sweden)

    Alexander Martínez Contreras

    2012-06-01

    Full Text Available In the fields of Medicine and bovine production, there is a wide variety of diseases affecting reproduction, in relation to the number of live births, the interval between births and open days, among others. Some of these diseases produce abortions and embryonic death, which explain the alteration of reproductive parameters. Many of these diseases have an infectious origin, such as parasites, bacteria, viruses and fungi, which are transmitted among animals. Besides, some of them have zoonotic features that generate problems to human health. Among these agents, the Neospora caninum, protozoan stands out. Its life cycle is fulfilled in several species of animals like the dog and the coyote. These two act as its definitive hosts and the cattle as its intermediary host. The Neospora caninum causes in the infected animals, reproductive disorders, clinical manifestations and decreased production which affects productivity of small, medium and large producers. Because of this, diagnostic techniques that allow understanding the epidemiological behavior of this disease have been developed. However in spite of being a major agent in the bovine reproductive health, few studies have been undertaken to determine the prevalence of this agent around the world. Therefore, the objective of this review was to collect updated information on the behavior of this parasite, targeting its epidemiology, its symptoms, its impact on production and the methods of its control and prevention.

  16. Diuretics: a review and update.

    Science.gov (United States)

    Roush, George C; Kaur, Ramdeep; Ernst, Michael E

    2014-01-01

    Diuretics have been recommended as first-line treatment of hypertension and are also valuable in the management of hypervolemia and electrolyte disorders. This review summarizes the key features of the most commonly used diuretics. We then provide an update of clinical trials for diuretics during the past 5 years. Compared to other classes of medications, thiazide diuretics are at least as effective in reducing cardiovascular events (CVEs) in patients with hypertension and are more effective than β-blockers and angiotensin-converting enzyme inhibitors in reducing stroke. Observational cohort data and a network analysis have shown that CVEs are lowered by one-fifth from chlorthalidone when compared to the commonly used thiazide, hydrochlorothiazide. Relative to placebo, chlorthalidone increases life expectancy. In those aged 80 years and older, the diuretic, indapamide, lowers CVEs relative to placebo. The aldosterone antagonist, eplerenone, lowers total mortality in early congestive heart failure. The benefit of eplerenone following acute myocardial infarction (MI) is limited to administration within 3 to 6 days post-MI. Aldosterone antagonists have been shown to lower the incidence of sudden cardiac death and to reduce proteinuria. In the setting of heart failure, long acting loop diuretics azosemide and torasemide are more effective in improving heart failure outcomes than the far more commonly used short acting furosemide. Evening dosing of diuretics appears to lower CVEs relative to morning dosing. In conclusion, diuretics are a diverse class of drugs that remain extremely important in the management of hypertension and hypervolemic states.

  17. Research reactor fuel - an update

    International Nuclear Information System (INIS)

    Finlay, M.R.; Ripley, M.I.

    2003-01-01

    In the two years since the last ANA conference there have been marked changes in the research reactor fuel scene. A new low-enriched uranium (LEU) fuel, 'monolithic' uranium molybdenum, has shown such promise in initial trials that it may be suitable to meet the objectives of the Joint Declaration signed by Presidents Bush and Putin to commit to converting all US and Russian research reactors to LEU by 2012. Development of more conventional aluminium dispersion UMo LEU fuel has continued in the meantime and is entering the final qualification stage of multiple full sized element irradiations. Despite this progress, the original 2005 timetable for UMo fuel qualification has slipped and research reactors, including the RRR, may not convert from silicide to UMo fuel before 2007. The operators of the Swedish R2 reactor have been forced to pursue the direct route of qualifying a UMo lead test assembly (LTA) in order to meet spent fuel disposal requirements of the Swedish law. The LTA has recently been fabricated and is expected to be loaded shortly into the R2 reactor. We present an update of our previous ANA paper and details of the qualification process for UMo fuel

  18. Hypersensitivity and vaccines: an update.

    Science.gov (United States)

    Barbaud, Annick; Deschildre, Antoine; Waton, Julie; Raison-Peyron, Nadia; Tréchot, Philippe

    2013-04-01

    Allergic reactions to vaccines can be classified as sensitivity to one of the vaccine components, pseudo-allergic reactions, often after hyperimmunization, and exacerbation of atopic symptoms or vasculitis. Pseudo-allergic reactions, some possibly due to hyperimmunization, are probably more common than true allergies. Atopic reactions should not be confused with the "flash" phenomenon, defined as an exacerbation of an allergic reaction due to a reduction in the allergic reactivity threshold following the vaccine injection. BCGitis occurs frequently, and for this reason, guidelines for Bacillus Calmette-Guérin (BCG) have been modified. The vaccine is now reserved for people at risk of exposure to Mycobacterium tuberculosis. This review provides an update on the vaccination modalities for people allergic to eggs, on the assessment that should be performed when a reaction occurs due to tetanus vaccination, on the urticaria after hepatitis vaccination, on an aluminum granuloma, which is more and more frequent in young children, and vasculitis after flu vaccination and BCGitis. The side effects associated with new, recently released vaccines, such as anti-influenza A H1N1 or anti-human papilloma virus (HPV) will also be presented.

  19. Passive Nuclear Plants Program (UPDATE)

    International Nuclear Information System (INIS)

    Chimeno, M. A.

    1998-01-01

    The light water passive plants program (PCNP), today Advanced Nuclear Power Plants Program (PCNA), was constituted in order to reach the goals of the Spanish Electrical Sector in the field of advanced nuclear power plants, optimize the efforts of all Spanish initiatives, and increase joint presence in international projects. The last update of this program, featured in revision 5th of the Program Report, reflects the consolidation of the Spanish sector's presence in International programs of the advanced power plants on the basis of the practically concluded American ALWR program. Since the beginning of the program , the PCNP relies on financing from the Electrical sector, Ocide, SEPI-Endesa, Westinghouse, General Electric, as well as from the industrial cooperators, Initec, UTE (Initec- Empresarios Agrupados), Ciemat, Enusa, Ensa and Tecnatom. The program is made up of the following projects, already concluded: - EPRI's Advanced Light Water Plants Certification Project - Westinghouse's AP600 Project - General Electric's SBWR Project (presently paralyzed) and ABWR project Currently, the following project are under development, at different degrees of advance: - EPP project (European Passive Plant) - EBWR project (European Advanced Boiling Water Reactor)

  20. ADVISORY ON UPDATED METHODOLOGY FOR ...

    Science.gov (United States)

    The National Academy of Sciences (NAS) published the Biological Effects of Ionizing Radiation (BEIR) committee's report (BEIR VII) on risks from ionizing radiation exposures in 2006. The Committee analyzed the most recent epidemiology from the important exposed cohorts and factored in changes resulting from the updated analysis of dosimetry for the Japanese atomic bomb survivors. To the extent practical, the Committee also considered relevant radiobiological data, including that from the Department of Energy's low dose effects research program. Based on the review of this information, the Committee proposed a set of models for estimating risks from low-dose ionizing radiation. ORIA then prepared a white paper revising the Agency's methodology for estimating cancer risks from exposure to ionizing radiation in light of this report and other relevant information. This is the first product to be developed as a result of the BEIR VII report. We requested that the SAB conduct an advisory during the development of this methodology. The second product to be prepared will be a revised version of the document,

  1. Expert panel on weight loss surgery: executive report update.

    Science.gov (United States)

    Blackburn, George L; Hutter, Matthew M; Harvey, Alan M; Apovian, Caroline M; Boulton, Hannah R W; Cummings, Susan; Fallon, John A; Greenberg, Isaac; Jiser, Michael E; Jones, Daniel B; Jones, Stephanie B; Kaplan, Lee M; Kelly, John J; Kruger, Rayford S; Lautz, David B; Lenders, Carine M; Lonigro, Robert; Luce, Helen; McNamara, Anne; Mulligan, Ann T; Paasche-Orlow, Michael K; Perna, Frank M; Pratt, Janey S A; Riley, Stancel M; Robinson, Malcolm K; Romanelli, John R; Saltzman, Edward; Schumann, Roman; Shikora, Scott A; Snow, Roger L; Sogg, Stephanie; Sullivan, Mary A; Tarnoff, Michael; Thompson, Christopher C; Wee, Christina C; Ridley, Nancy; Auerbach, John; Hu, Frank B; Kirle, Leslie; Buckley, Rita B; Annas, Catherine L

    2009-05-01

    Rapid shifts in the demographics and techniques of weight loss surgery (WLS) have led to new issues, new data, new concerns, and new challenges. In 2004, this journal published comprehensive evidence-based guidelines on WLS. In this issue, we've updated those guidelines to assure patient safety in this fast-changing field. WLS involves a uniquely vulnerable population in need of specialized resources and ongoing multidisciplinary care. Timely best-practice updates are required to identify new risks, develop strategies to address them, and optimize treatment. Findings in these reports are based on a comprehensive review of the most current literature on WLS; they directly link patient safety to methods for setting evidence-based guidelines developed from peer-reviewed scientific publications. Among other outcomes, these reports show that WLS reduces chronic disease risk factors, improves health, and confers a survival benefit on those who undergo it. The literature also shows that laparoscopy has displaced open surgery as the predominant approach; that government agencies and insurers only reimburse procedures performed at accredited WLS centers; that best practice care requires close collaboration between members of a multidisciplinary team; and that new and existing facilities require wide-ranging changes to accommodate growing numbers of severely obese patients. More than 100 specialists from across the state of Massachusetts and across the many disciplines involved in WLS came together to develop these new standards. We expect them to have far-reaching effects of the development of health care policy and the practice of WLS.

  2. Information services directory: An Update of 5/87

    International Nuclear Information System (INIS)

    1989-03-01

    The Information Services Directory is intended to facilitate dissemination of information. The Directory is produced by the Information Services Division of OCRWM's Office of External Relations and Policy and will be updated periodically. This is the second such update since its issuance in August 1986. It is a reference document that lists the sources of program information available to States, Indian Tribes and the public. Chapter I of this Directory describes current program information sources, including the OCRWM Bulletin, the Electronic Bulletin Board (INFOLINK) and other periodic publications produced by OCRWM and DOE's Office of Scientific and Technical Information (OSTI). Chapter II is an index of DOE, State and Federal Agency contacts. Chapter III provides a directory of DOE technical information and includes descriptions of computerized data bases and other resources. Chapter IV enumerates Congressional Committees and Subcommittees that have jurisdiction over various components of the Civilian Radioactive Waste Management Program, and Chapter V lists DOE Reading Rooms and Information Offices, NRC Local Public Document Rooms, and public libraries in the State of Nevada that are on one or more of OCRWM's mailing lists. Chapter VI is an index of systems and Chapter VII offers listings of selected publications

  3. Update in cardiology: vascular risk and cardiac rehabilitation.

    Science.gov (United States)

    Galve, Enrique; Cordero, Alberto; Bertomeu-Martínez, Vicente; Fácila, Lorenzo; Mazón, Pilar; Alegría, Eduardo; Fernández de Bobadilla, Jaime; García-Porrero, Esteban; Martínez-Sellés, Manuel; González-Juanatey, José Ramón

    2015-02-01

    As in other fields, understanding of vascular risk and rehabilitation is constantly improving. The present review of recent epidemiological update shows how far we are from achieving good risk factor control: in diet and nutrition, where unhealthy and excessive societal consumption is clearly increasing the prevalence of obesity; in exercise, where it is difficult to find a balance between benefit and risk, despite systemization efforts; in smoking, where developments center on programs and policies, with the electronic cigarette seeming more like a problem than a solution; in lipids, where the transatlantic debate between guidelines is becoming a paradigm of the divergence of views in this extensively studied area; in hypertension, where a nonpharmacological alternative (renal denervation) has been undermined by the SYMPLICITY HTN-3 setback, forcing a deep reassessment; in diabetes mellitus, where the new dipeptidyl peptidase-4 and sodium-glucose cotransporter type 2 inhibitors and glucagon like peptide 1 analogues have contributed much new information and a glimpse of the future of diabetes treatment, and in cardiac rehabilitation, which continues to benefit from new information and communication technologies and where clinical benefit is not hindered by advanced diseases, such as heart failure. Our summary concludes with the update in elderly patients, whose treatment criteria are extrapolated from those of younger patients, with the present review clearly indicating that should not be the case. Copyright © 2014 Sociedad Española de Cardiología. Published by Elsevier España, S.L.U. All rights reserved.

  4. Food policy an ethics

    DEFF Research Database (Denmark)

    Coff, Christian Eyde; Kemp, Peter

    2014-01-01

    makes of food policy a highly complex and diverse area. The entry opens with at description of the concept of policy and food policy and how it relates to ethical principles and values. The fourth section discusses some influental definitions of food policy. The final section contains a description......This entry gives an overview of food policy and major ethical principles that in the last decades have been proposed and advocated for in debates on food policy. Food policies touch upon a vast area of interrelated policies (like health, transport, environment, poverty, animal welfare etc.) which...... of ethical principles and ideas of relevance to food policy....

  5. Food policy an ethics

    DEFF Research Database (Denmark)

    Coff, Christian Eyde; Kemp, Peter

    2014-01-01

    This entry gives an overview of food policy and major ethical principles that in the last decades have been proposed and advocated for in debates on food policy. Food policies touch upon a vast area of interrelated policies (like health, transport, environment, poverty, animal welfare etc.) which...... makes of food policy a highly complex and diverse area. The entry opens with at description of the concept of policy and food policy and how it relates to ethical principles and values. The fourth section discusses some influental definitions of food policy. The final section contains a description...... of ethical principles and ideas of relevance to food policy....

  6. Update on Radioactive Waste Management in the UK

    International Nuclear Information System (INIS)

    Dalton, John; McCall, Ann

    2003-01-01

    This paper provides a brief background to the current position in the United Kingdom (UK) and provides an update on the various developments and initiatives within the field of radioactive waste management that have been taking place during 2002/03. These include: The UK Government's Department of Trade and Industry (DTi) review of UK energy policy; The UK Government's (Department of Environment, Food and Rural Affairs (Defra) and Devolved Administrations*) consultation program; The UK Government's DTi White Paper, 'Managing the Nuclear Legacy: A Strategy for Action'; Proposals for improved regulation of Intermediate Level Waste (ILW) conditioning and packaging. These various initiatives relate, in Nirex's opinion, to the three sectors of the industry and this paper will provide a comment on these initiatives in light of the lessons that Nirex has learnt from past events and suggest some conclusions for the future

  7. Research for health policy

    National Research Council Canada - National Science Library

    Bell, Erica

    2010-01-01

    ... Explicit, implicit, and pragmatic dimensions of policy-maker's needs and context 31 Constraints on policy-makers 32 Deciphering trade-offs 33 The policy-problem: deciphering uncertainty and the problem of innovation 34 A tool for deciphering policy problems 35 The different components of the policy problem 37 Recommended reading 38 Case studies in...

  8. Policies and strategies for radioactive waste management

    International Nuclear Information System (INIS)

    2009-01-01

    (organizational, technical and legislative), and on future needs and waste arisings. The technical procedures proposed for the waste types in the country should be politically, technically and economically feasible. When selecting a set of technological procedures, an appropriate end point must be identified, usually a suitable disposal option. The steps in formulating and implementing the strategy include selecting the technological procedures, allocating the responsibility for implementing the identified procedures, establishing supervisory mechanisms and developing implementation plans. Policies and strategies may need to be updated because of new national circumstances (legislative changes, plans for new nuclear facilities), new international agreements and/or experience obtained with the original policy and strategy. The lead in making changes should be taken by the body responsible for the initial formulation of the policy (government) and strategy (waste management organization); but all relevant parties in the country should be involved and consulted in this process. (author)

  9. AAP Updates Recommendations on Car Seats

    Science.gov (United States)

    ... Size Email Print Share AAP Updates Recommendations on Car Seats Page Content Article Body Children should ride ... of approved car safety seats. Healthy Children Radio: Car Seat Safety Dennis Durbin, MD, FAAP, lead author ...

  10. Rapid Update Cycle (RUC) [13 km

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Rapid Update Cycle (RUC) weather forecast model was developed by the National Centers for Environmental Prediction (NCEP). On May 1, 2012, the RUC was replaced...

  11. Model Updating Nonlinear System Identification Toolbox Project

    Data.gov (United States)

    National Aeronautics and Space Administration — ZONA Technology proposes to develop an enhanced model updating nonlinear system identification (MUNSID) methodology by adopting the flight data with state-of-the-art...

  12. Veterans and agent orange: update 2000

    National Research Council Canada - National Science Library

    Division of Health Promotion and Disease Prevention Staff; Institute of Medicine, Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides

    2001-01-01

    Veterans and Agent Orange: Update 2000 examines the state of the scientific evidence regarding associations between diseases and exposure to dioxin and other chemical compounds in herbicides used in Vietnam...

  13. Rapid Update Cycle (RUC) [20 km

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Rapid Update Cycle (RUC) weather forecast model was developed by the National Centers for Environmental Prediction (NCEP). On May 1, 2012, the RUC was replaced...

  14. NODA for EPA's Updated Ozone Transport Modeling

    Science.gov (United States)

    Find EPA's NODA for the Updated Ozone Transport Modeling Data for the 2008 Ozone National Ambient Air Quality Standard (NAAQS) along with the ExitExtension of Public Comment Period on CSAPR for the 2008 NAAQS.

  15. Earth Observing System Covariance Realism Updates

    Science.gov (United States)

    Ojeda Romero, Juan A.; Miguel, Fred

    2017-01-01

    This presentation will be given at the International Earth Science Constellation Mission Operations Working Group meetings June 13-15, 2017 to discuss the Earth Observing System Covariance Realism updates.

  16. Policy entrepreneurship and policy networks in healthcare systems - the case of Israel's pediatric dentistry reform.

    Science.gov (United States)

    Cohen, Nissim; Horev, Tuvia

    2017-01-01

    Can the entry of a policy entrepreneur challenge the equilibrium of a policy network and promote changes that might clash with the goals of powerful civil-servants and/or interest groups and, if so, why and how? Our goal is to examine two sides of the same coin: how does an in-depth analysis of Israel's dental care reform enrich our understanding of policy networks and policy entrepreneurship? Second, how does the literature on policy networks and policy entrepreneurship help us understand this reform? Based on a theoretical framework that appears in the literature of policy entrepreneurship and policy networks, we analyze the motivations, goals and strategies of the main actors involved in the process of reforming pediatric dental care in Israel. We demonstrate how a policy entrepreneur navigated within a policy network and managed to promote a reform that, until his appearance, no one else in that network had succeeded in enacting. Our goals are advanced through a case study of a reform in pediatric dentistry implemented in Israel in 2010. It rests on textual analyses of the literature, reports, committee minutes, parliamentary proceedings, print and online media, and updates in relevant legislation and case law between 2009 and 2015. In addition, the case study draws on the insights of one of the authors (TH), who played a role in the reform process. Historical circumstances and the Israeli public's longstanding lack of interest in changing the existing model as well as interest groups that preferred the dominance of the private sector in the dental healthcare system kept that area out of the services supplied, universally, under the National Health Insurance Law. This situation changed significantly following the publication in 2007 of a policy analysis that contributed to shifts in the motivations and balance of power within the policy network, which in turn prepared the ground for a policy change. In this environment a determined policy entrepreneur, who

  17. Environmental regulatory update table, July 1991

    Energy Technology Data Exchange (ETDEWEB)

    Houlberg, L.M.; Hawkins, G.T.; Salk, M.S.

    1991-08-01

    This Environmental Regulatory Update Table (July 1991) provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  18. Environmental Regulatory Update Table, November 1991

    Energy Technology Data Exchange (ETDEWEB)

    Houlberg, L.M.; Hawkins, G.T.; Salk, M.S.

    1991-12-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  19. Environmental Regulatory Update Table, April 1989

    International Nuclear Information System (INIS)

    Houlberg, L.; Langston, M.E.; Nikbakht, A.; Salk, M.S.

    1989-05-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action

  20. Environmental Regulatory Update Table, December 1991

    Energy Technology Data Exchange (ETDEWEB)

    Houlberg, L.M.; Hawkins, G.T.; Salk, M.S.

    1992-01-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  1. Environmental regulatory update table, March 1989

    International Nuclear Information System (INIS)

    Houlberg, L.; Langston, M.E.; Nikbakht, A.; Salk, M.S.

    1989-04-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action

  2. Environmental regulatory update table, March 1989

    Energy Technology Data Exchange (ETDEWEB)

    Houlberg, L.; Langston, M.E.; Nikbakht, A.; Salk, M.S.

    1989-04-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  3. Update of Part 61 impacts analysis methodology

    International Nuclear Information System (INIS)

    Oztunali, O.I.; Roles, G.W.

    1986-01-01

    The US Nuclear Regulatory Commission is expanding the impacts analysis methodology used during the development of the 10 CFR Part 61 rule to allow improved consideration of costs and impacts of disposal of waste that exceeds Class C concentrations. The project includes updating the computer codes that comprise the methodology, reviewing and updating data assumptions on waste streams and disposal technologies, and calculation of costs for small as well as large disposal facilities. This paper outlines work done to date on this project

  4. Update of Part 61 impacts analysis methodology

    International Nuclear Information System (INIS)

    Oztunali, O.I.; Roles, G.W.; US Nuclear Regulatory Commission, Washington, DC 20555)

    1985-01-01

    The US Nuclear Regulatory Commission is expanding the impacts analysis methodology used during the development of the 10 CFR Part 61 regulation to allow improved consideration of costs and impacts of disposal of waste that exceeds Class C concentrations. The project includes updating the computer codes that comprise the methodology, reviewing and updating data assumptions on waste streams and disposal technologies, and calculation of costs for small as well as large disposal facilities. This paper outlines work done to date on this project

  5. Environmental Regulatory Update Table, April 1989

    Energy Technology Data Exchange (ETDEWEB)

    Houlberg, L.; Langston, M.E.; Nikbakht, A.; Salk, M.S.

    1989-05-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  6. Environmental Regulatory Update Table, August 1991

    Energy Technology Data Exchange (ETDEWEB)

    Houlberg, L.M., Hawkins, G.T.; Salk, M.S.

    1991-09-01

    This Environmental Regulatory Update Table (August 1991) provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  7. Environmental Regulatory Update Table, September 1991

    Energy Technology Data Exchange (ETDEWEB)

    Houlberg, L.M.; Hawkins, G.T.; Salk, M.S.

    1991-10-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  8. Environmental Regulatory Update Table, October 1991

    Energy Technology Data Exchange (ETDEWEB)

    Houlberg, L.M.; Hawkins, G.T.; Salk, M.S.

    1991-11-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  9. Updating Dosimetry for Emergency Response Dose Projections.

    Science.gov (United States)

    DeCair, Sara

    2016-02-01

    In 2013, the U.S. Environmental Protection Agency (EPA) proposed an update to the 1992 Protective Action Guides (PAG) Manual. The PAG Manual provides guidance to state and local officials planning for radiological emergencies. EPA requested public comment on the proposed revisions, while making them available for interim use by officials faced with an emergency situation. Developed with interagency partners, EPA's proposal incorporates newer dosimetric methods, identifies tools and guidelines developed since the current document was issued, and extends the scope of the PAGs to all significant radiological incidents, including radiological dispersal devices or improvised nuclear devices. In order to best serve the emergency management community, scientific policy direction had to be set on how to use International Commission on Radiological Protection Publication 60 age groups in dose assessment when implementing emergency guidelines. Certain guidelines that lend themselves to different PAGs for different subpopulations are the PAGs for potassium iodide (KI), food, and water. These guidelines provide age-specific recommendations because of the radiosensitivity of the thyroid and young children with respect to ingestion and inhalation doses in particular. Taking protective actions like using KI, avoiding certain foods or using alternative sources of drinking water can be relatively simple to implement by the parents of young children. Clear public messages can convey which age groups should take which action, unlike how an evacuation or relocation order should apply to entire households or neighborhoods. New in the PAG Manual is planning guidance for the late phase of an incident, after the situation is stabilized and efforts turn toward recovery. Because the late phase can take years to complete, decision makers are faced with managing public exposures in areas not fully remediated. The proposal includes quick-reference operational guidelines to inform re-entry to

  10. Science-based regulatory and policy considerations in nutrition.

    Science.gov (United States)

    Schneeman, Barbara

    2015-05-01

    Scientific evidence is necessary for the development of effective and enforceable regulations and government policy. To use scientific information appropriately, a systematic approach is needed for review and evaluation of the evidence. Federal agencies in the United States have developed useful approaches for such a review and evaluation to develop nutrition labeling, including health claims, and for updating of the Dietary Guidelines for Americans. The WHO is using a systematic evaluation process to update its recommendations on diet and health. The results of such reviews also highlight research needs to address relevant gaps in our knowledge. © 2015 American Society for Nutrition.

  11. Working Memory Updating as a Predictor of Academic Attainment

    Science.gov (United States)

    Lechuga, M. Teresa; Pelegrina, Santiago; Pelaez, Jose L.; Martin-Puga, M. Eva; Justicia, M. Jose

    2016-01-01

    There is growing evidence supporting the importance of executive functions, and specifically working memory updating (WMU), for children's academic achievement. This study aimed to assess the specific contribution of updating to the prediction of academic performance. Two updating tasks, which included different updating components, were…

  12. Nuclear technology review 2005 update

    International Nuclear Information System (INIS)

    2005-08-01

    The year 2004 marked the 50th anniversary of civilian nuclear power generation. While the current outlook for nuclear energy remains mixed, there is clearly a sense of rising expectations. Both the OECD International Energy Agency and the IAEA adjusted their medium-term projections for nuclear power upwards. The IAEA now projects 423 - 592 GW(e) of nuclear power installed worldwide in 2030, compared to 366 GW(e) at the end of 2004. This is driven by nuclear power's performance record, by growing energy needs around the world coupled with rising oil and natural gas prices, by new environmental constraints including entry-into-force of the Kyoto Protocol, by concerns about energy supply security in a number of countries, and by ambitious expansion plans in several key countries. National research on advanced reactor designs continues on all reactor categories - water cooled, gas cooled, liquid metal cooled, and hybrid systems. Five members of the US-initiated Generation IV International Forum (GIF) signed a framework agreement on international collaboration in research and development on Generation IV nuclear energy systems in February 2005. The IAEA's International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO) grew to 23 members. It completed a series of case studies testing its assessment methodology and the final report on the updated INPRO methodology was published in December. The realization of the International Thermonuclear Experimental Reactor, ITER, came closer with the announcement on 28 June 2005 by the ITER parties. The aim of ITER is to demonstrate the scientific and technological feasibility of fusion energy by constructing a functional fusion power plant. Nuclear technology developments are rapid and cover many fields of application. Not all can be covered in this update review, but certain key areas and trends are covered where these are seen to be of significant interest to IAEA Member States, and which are of relevance to and have

  13. Dutch Venous Ulcer guideline update.

    Science.gov (United States)

    Maessen-Visch, M Birgitte; de Roos, Kees-Peter

    2014-05-01

    The revised guideline of 2013 is an update of the 2005 guideline "venous leg ulcer". In this special project four separate guidelines (venous leg ulcer, varicose veins, compression therapy and deep venous disorders) were revised and developed simultaneously. A meeting was held including representatives of any organisation involved in venous disease management including patient organizations and health insurance companies. Eighteen clinical questions where defined, and a new strategy was used to accelerate the process. This resulted in two new and two revised guidelines within one year. The guideline committee advises use of the C of the CEAP classification as well as the Venous Clinical Severity Score (VCSS) and a Quality of life (QoL) score in the assessment of clinical signs. These can provide insight into the burden of disease and the effects of treatment as experienced by the patient. A duplex ultrasound should be performed in every patient to establish the underlying aetiology and to evaluate the need for treatment (which is discussed in a separate guideline). The use of the TIME model for describing venous ulcers is recommended. There is no evidence for antiseptic or antibiotic wound care products except for a Cochrane review in which some evidence is presented for cadexomer iodine. Signs of infection are the main reason for the use of oral antibiotics. When the ulcer fails to heal the use of oral aspirin and pentoxifylline can be considered as an adjunct. For the individual patient, the following aspects should be considered: the appearance of the ulcer (amount of exudate) according to the TIME model, the influence of wound care products on moisturising the wound, frequency of changing compression bandages, pain and allergies. The cost of the dressings should also be considered. Education and training of patients t improves compliance with compression therapy but does not influence wound healing rates. © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

  14. Obesity management: Update on orlistat

    Directory of Open Access Journals (Sweden)

    Belinda S Drew

    2008-01-01

    Full Text Available Belinda S Drew, Andrew F Dixon, John B DixonCentre for Obesity Research and Education, Monash University, Melbourne, AustraliaAbstract: Over the past 20 years obesity has become a worldwide concern of frightening proportion. The World Health Organization estimates that there are over 400 million obese and over 1.6 billion overweight adults, a figure which is projected to almost double by 2015. This is not a disease restricted to adults – at least 20 million children under the age of 5 years were overweight in 2005 (WHO 2006. Overweight and obesity lead to serious health consequences including coronary artery disease, stroke, type-2 diabetes, heart failure, dyslipidemia, hypertension, reproductive and gastrointestinal cancers, gallstones, fatty liver disease, osteoarthritis and sleep apnea (Padwal et al 2003.Modest weight loss in the obese of between 5% and 10% of bodyweight is associated with improvements in cardiovascular risk profiles and reduced incidence of type 2 diabetes (Goldstein 1992; Avenell et al 2004; Padwal and Majumdar 2007. Orlistat, a gastric and pancreatic lipase inhibitor that reduces dietary fat absorption by approximately 30%, has been approved for use for around ten years (Zhi et al 1994; Hauptman 2000. There is now a growing body of evidence to suggest that Orlistat assists weight loss and that it may also have additional benefits. The aim of this review is to provide a brief update on the current literature studying the efficacy, safety and significance of the use of Orlistat in clinical practice.Keywords: obese, weight, diet, orlistat, hypertension, cholesterol

  15. Policy Archaeology: A New Policy Studies Methodology.

    Science.gov (United States)

    Scheurich, James Joseph

    1994-01-01

    Discusses policy archaeology, a radically different approach to policy studies in education drawn from the poststructuralist work of Foucault. Policy archaeology examines the social construction of problems before they become visible, focusing on five social regularities (race, gender, class, governmentality, and professionalization) comprising…

  16. A Supply and Demand Update of the Molybdenum-99 Market

    International Nuclear Information System (INIS)

    2012-08-01

    Medical diagnostic imaging techniques using technetium-99m account for roughly 80% of all nuclear medicine procedures, representing over 30 million examinations worldwide every year. Disruptions in the supply chain of these medical isotopes - which have half-lives of 66 hours for molybdenum-99 ( 99 Mo) and 6 hours for its daughter isotope, technetium-99m (' 99m Tc), and thus must be produced continually - can lead to cancellations or delays in important medical testing services. Unfortunately, supply reliability has declined over the past decade due to unexpected or extended shutdowns at the few ageing 99 Mo-producing research reactor and processing facilities. These shutdowns have created global supply shortages. In 2011, the OECD Nuclear Energy Agency (NEA), along with its High-level Group on the Security of Supply of Medical Radioisotopes (HLG-MR), released a report that presents the reasons behind the lack of infrastructure that led to global supply shortages and a policy approach to encourage long-term medical isotope supply security. In that report, The Supply of Medical Radioisotopes: The Path to Reliability, the NEA also provides potential futures of supply and demand out to 2030. Since the release of The Path there have been a number of changes in the market and therefore this document provides an update on the 2011 supply and demand situation. This update is based on information provided to the NEA by members of the HLG-MR and other key stakeholders. This presentation of supply and demand future scenarios for the 99 Mo market revises previous NEA future scenarios based on new data and target conversion commitments from the supply chain. The update, unfortunately, does not present a more optimistic future scenario than previous presentations - the concern around the uneconomic situation of the supply chain continues to dominate the potential for new projects. This results in the potential for long-term shortages within the decade. However, there are a

  17. Environmental policy performance revisited

    DEFF Research Database (Denmark)

    Daugbjerg, Carsten; Sønderskov, Kim Mannemar

    2012-01-01

    Studies of environmental policy performance tend to concentrate on the impact of particular policy institutions or of single policy instruments. However, environmental policies most often consist of a package of policy instruments. Further, these studies pay no or very little attention to policy......-country variation in organic food consumption is explained by differences in the packages of policy instruments applied, controlling for numerous systemic and individual-level alternative explanations. The analysis suggests that for environmental and political reasons, governments should apply more demand......-side instruments when introducing environmental policies....

  18. Policy Feedback System (PFS)

    Data.gov (United States)

    Social Security Administration — The Policy Feedback System (PFS) is a web application developed by the Office of Disability Policy Management Information (ODPMI) team that gathers empirical data...

  19. Quantifying Update Effects in Citizen-Oriented Software

    Directory of Open Access Journals (Sweden)

    Ion Ivan

    2009-02-01

    Full Text Available Defining citizen-oriented software. Detailing technical issues regarding update process in this kind of software. Presenting different effects triggered by types of update. Building model for update costs estimation, including producer-side and consumer-side effects. Analyzing model applicability on INVMAT – large scale matrix inversion software. Proposing a model for update effects estimation. Specifying ways for softening effects of inaccurate updates.

  20. Partial updating of clinical practice guidelines often makes more sense than full updating: a systematic review on methods and the development of an updating procedure.

    Science.gov (United States)

    Becker, Monika; Neugebauer, Edmund A M; Eikermann, Michaela

    2014-01-01

    To conduct a systematic review of the methods used to determine when and how to update clinical practice guidelines (CPGs) and develop a procedure for updating CPGs. We searched MEDLINE, Embase, and the Cochrane Methodology Register for methodological publications on updating CPGs. Guideline development manuals were obtained from the Web sites of guideline-developing organizations. Using the information obtained from these records, a procedure for updating CPGs was developed. A total of 5,116 journal articles were screened, and seven articles met the criteria for inclusion. Forty-seven manuals were included; of these, eight included details about the methods used to update the guidelines. Most of the included publications focused on assessing whether the CPGs needed updating and not on how to update them. The developed procedure includes a systematic monitoring system and a scheduled process for updating the CPGs, which includes guidance on how to determine the type and scope of an update. Partial updating often makes more sense than updating the whole CPG because topics and recommendations differ in terms of the need for updating. Guideline developers should implement a systematic updating procedure that includes an ongoing monitoring system that is appropriate for the nature of the guideline topics and the capabilities of the developers. Copyright © 2014 Elsevier Inc. All rights reserved.

  1. Updated NGNP Fuel Acquisition Strategy

    Energy Technology Data Exchange (ETDEWEB)

    David Petti; Tim Abram; Richard Hobbins; Jim Kendall

    2010-12-01

    A Next Generation Nuclear Plant (NGNP) fuel acquisition strategy was first established in 2007. In that report, a detailed technical assessment of potential fuel vendors for the first core of NGNP was conducted by an independent group of international experts based on input from the three major reactor vendor teams. Part of the assessment included an evaluation of the credibility of each option, along with a cost and schedule to implement each strategy compared with the schedule and throughput needs of the NGNP project. While credible options were identified based on the conditions in place at the time, many changes in the assumptions underlying the strategy and in externalities that have occurred in the interim requiring that the options be re-evaluated. This document presents an update to that strategy based on current capabilities for fuel fabrication as well as fuel performance and qualification testing worldwide. In light of the recent Pebble Bed Modular Reactor (PBMR) project closure, the Advanced Gas Reactor (AGR) fuel development and qualification program needs to support both pebble and prismatic options under the NGNP project. A number of assumptions were established that formed a context for the evaluation. Of these, the most important are: • Based on logistics associated with the on-going engineering design activities, vendor teams would start preliminary design in October 2012 and complete in May 2014. A decision on reactor type will be made following preliminary design, with the decision process assumed to be completed in January 2015. Thus, no fuel decision (pebble or prismatic) will be made in the near term. • Activities necessary for both pebble and prismatic fuel qualification will be conducted in parallel until a fuel form selection is made. As such, process development, fuel fabrication, irradiation, and testing for pebble and prismatic options should not negatively influence each other during the period prior to a decision on reactor type

  2. Dissociating Working Memory Updating and Automatic Updating: The Reference-Back Paradigm

    Science.gov (United States)

    Rac-Lubashevsky, Rachel; Kessler, Yoav

    2016-01-01

    Working memory (WM) updating is a controlled process through which relevant information in the environment is selected to enter the gate to WM and substitute its contents. We suggest that there is also an automatic form of updating, which influences performance in many tasks and is primarily manifested in reaction time sequential effects. The goal…

  3. IEA Bioenergy task 40. Country report for the Netherlands. Update 2006

    International Nuclear Information System (INIS)

    Junginger, M.; De Wit, M.; Faaij, A.

    2006-09-01

    Short-term objectives of the IEA Bioenergy Task 40 'Sustainable International Bio-energy Trade: Securing Supply and Demand' are amongst other objectives to present an overview of development of biomass markets in various parts of the world and to identify existing barriers hampering development of a (global) commodity market (e.g. policy framework, ecology, economics). As in most countries biomass is a relatively new (though quickly growing) commodity, relatively little information is available on e.g. the traded volumes and prices of various biomass streams, policies and regulations on biomass use and trade, and existing and perceived barriers. This country report aims to provide an overview of these issues for the Netherlands, and also sets the first step to make an inventory of barriers as perceived by various Dutch stakeholders. The information gathered in this report is to a large extent based on existing statistics and reports from Dutch institutions. The literature data is complemented by additional information obtained from stakeholders, such as utilities, biomass traders, the port of Rotterdam, policy makers and custom institutions. In some cases, the data source was left anonymous because of the confidential nature of the data concerned. This report was first published in 2005. In this updated 2006 version, additional data has been collected for the year 2005, mainly concerning the import of biomass and renewable electricity. Also the policy section has been updated (situation September 2006), and some information on the use of biofuels has been added.

  4. "Updates to Model Algorithms & Inputs for the Biogenic ...

    Science.gov (United States)

    We have developed new canopy emission algorithms and land use data for BEIS. Simulations with BEIS v3.4 and these updates in CMAQ v5.0.2 are compared these changes to the Model of Emissions of Gases and Aerosols from Nature (MEGAN) and evaluated the simulations against observations. This has resulted in improvements in model evaluations of modeled isoprene, NOx, and O3. The National Exposure Research Laboratory (NERL) Atmospheric Modeling and Analysis Division (AMAD) conducts research in support of EPA mission to protect human health and the environment. AMAD research program is engaged in developing and evaluating predictive atmospheric models on all spatial and temporal scales for forecasting the air quality and for assessing changes in air quality and air pollutant exposures, as affected by changes in ecosystem management and regulatory decisions. AMAD is responsible for providing a sound scientific and technical basis for regulatory policies based on air quality models to improve ambient air quality. The models developed by AMAD are being used by EPA, NOAA, and the air pollution community in understanding and forecasting not only the magnitude of the air pollution problem, but also in developing emission control policies and regulations for air quality improvements.

  5. Important update of CERN Mail Services

    CERN Document Server

    IT Department

    2009-01-01

    The CERN Mail Services are evolving. In the course of June and July 2009, all CERN mailboxes will be updated with a new infrastructure for hosting mailboxes, running Exchange 2007. This update is taking place in order to provide the capacity upgrade for the constantly growing volume of CERN mailboxes. It is also the opportunity to provide a number of improvements to CERN mailboxes: new and improved Outlook Web Access (the web interface used to access your mailbox from a web browser, also known as "webmail"), new features in the Out-of-Office auto-reply assistant, easier spam management... The update will preserve the mailbox configuration and no specific action is required by users. During the next weeks, each mailbox will be individually notified of the upcoming update the day before it takes place. We invite all users to carefully read this notification as it will contain the latest information for this update. The mailbox will be unavailable for a short time during the ni...

  6. PUMA: The Positional Update and Matching Algorithm

    Science.gov (United States)

    Line, J. L. B.; Webster, R. L.; Pindor, B.; Mitchell, D. A.; Trott, C. M.

    2017-01-01

    We present new software to cross-match low-frequency radio catalogues: the Positional Update and Matching Algorithm. The Positional Update and Matching Algorithm combines a positional Bayesian probabilistic approach with spectral matching criteria, allowing for confusing sources in the matching process. We go on to create a radio sky model using Positional Update and Matching Algorithm based on the Murchison Widefield Array Commissioning Survey, and are able to automatically cross-match 98.5% of sources. Using the characteristics of this sky model, we create simple simulated mock catalogues on which to test the Positional Update and Matching Algorithm, and find that Positional Update and Matching Algorithm can reliably find the correct spectral indices of sources, along with being able to recover ionospheric offsets. Finally, we use this sky model to calibrate and remove foreground sources from simulated interferometric data, generated using OSKAR (the Oxford University visibility generator). We demonstrate that there is a substantial improvement in foreground source removal when using higher frequency and higher resolution source positions, even when correcting positions by an average of 0.3 arcmin given a synthesised beam-width of 2.3 arcmin.

  7. Updated uncertainty budgets for NIST thermocouple calibrations

    Science.gov (United States)

    Meyer, C. W.; Garrity, K. M.

    2013-09-01

    We have recently updated the uncertainty budgets for calibrations in the NIST Thermocouple Calibration Laboratory. The purpose for the updates has been to 1) revise the estimated values of the relevant uncertainty elements to reflect the current calibration facilities and methods, 2) provide uncertainty budgets for every standard calibration service offered, and 3) make the uncertainty budgets more understandable to customers by expressing all uncertainties in units of temperature (°C) rather than emf. We have updated the uncertainty budgets for fixed-point calibrations of type S, R, and B thermocouples and comparison calibrations of type R and S thermocouples using a type S reference standard. In addition, we have constructed new uncertainty budgets for comparison calibrations of type B thermocouples using a type B reference standard as well as using both a type S and type B reference standard (for calibration over a larger range). We have updated the uncertainty budgets for comparison calibrations of base-metal thermocouples using a type S reference standard and alternately using a standard platinum resistance thermometer reference standard. Finally, we have constructed new uncertainty budgets for comparison tests of noble-metal and base-metal thermoelements using a type S reference standard. A description of these updates is presented in this paper.

  8. Working for Policy

    NARCIS (Netherlands)

    Colebatch, H.K.; Hoppe, Robertus; Noordegraaf, Mirko

    2010-01-01

    Though democratic government calls for well-designed and implemented policy, there is surprisingly little expert guidance available for policy makers and politicians. Working for Policy fills that gap, addressing the nature of policy work and offering necessary guidance. The contributors bring

  9. Education Policy Outlook: Austria

    Science.gov (United States)

    Figueroa, Diana Toledo; Golden, Gillian; Giovinazzo, Manon; Peterka, Judith; Ullmann, Marie

    2017-01-01

    This policy profile on education in Austria is part of the "Education Policy Outlook" series, which presents comparative analysis of education policies and reforms across OECD countries. Building on the OECD's substantial comparative and sectoral knowledge base, the series offers a comparative outlook on education policy by providing…

  10. Using Updated Climate Accounting to Slow Global Warming Before 2035

    Science.gov (United States)

    Schultz, T.

    2015-12-01

    The current and projected worsening of climate impacts make clear the urgency of limiting the global mean temperature to 2°C over preindustrial levels. But while mitigation policy today may slow global warming at the end of the century, it will not keep global warming within these limits. This failure arises in large part from the climate accounting system used to inform this policy, which does not factor in several scientific findings from the last two decades, including: The urgent need to slow global warming before 2035. This can postpone the time the +1.5°C limit is passed, and is the only way to avoid the most serious long-term climate disruptions. That while it may mitigate warming by the end of the century, reducing emissions of CO2 alone, according to UNEP/WMO[1], will do "little to mitigate warming over the next 20-30 years," and "may temporarily enhance near-term warming as sulfate [cooling] is reduced." That the only emissions reductions that can slow warming before 2035 are focused on short-lived climate pollutants. A small increase in current mitigation funding could fund these projects, the most promising of which target emissions in regional climate "hot spots" like the Arctic and India.[2] To ensure policies can effectively slow global warming before 2035, a new climate accounting system is needed. Such an updated system is being standardized in the USA,[3] and has been proposed for use in ISO standards. The key features of this updated system are: consideration of all climate pollutants and their multi-faceted climate effects; use of time horizons which prioritize mitigation of near-term warming; a consistent and accurate accounting for "biogenic" CO2; protocols ensuring that new scientific findings are incorporated; and a distinct accounting for emissions affecting regional "hot spots". This accounting system also considers environmental impacts outside of climate change, a feature necessary to identify "win-win" projects with climate benefits

  11. Public Education Finance Systems in the United States and Funding Policies for Populations with Special Educational Needs

    Science.gov (United States)

    Verstegen, Deborah A.

    2011-01-01

    This research investigates state finance policies for public education using survey methodology. The purpose is to update previous work and the existing knowledge base in the field as well as to provide a compendium of finance and policy options that are used across the states to finance public elementary and secondary schools. Chief state school…

  12. Environmental policy in Japan

    Energy Technology Data Exchange (ETDEWEB)

    Tsuru, Shigeto; Weidner, H. (eds.)

    1989-01-01

    This book deals in English with the most important features of Japanese environmental policy in a number of individual articles by different authors. The various sections report on: 1. History and organization of environmental policy; 2. The role of non-governmental actors in environmental policy (large industries); 3. Special features of environmental policies and problems; 4. Classical pollution control areas: Regulations and effects; 5. Environmental problems in a broader perspective (nature conservation); 6. Policy areas with influence on environmental quality; 7. Environmental monitoring and reporting; 8. Japanese environmental policy in an international perspective (preventive policies, developing countries). (HSCH).

  13. Policy for Sustainable Entrepreneurship

    DEFF Research Database (Denmark)

    Watson, Rosina; Nielsen, Kristian Roed; Wilson, Hugh N.

    Sustainable entrepreneurship—entrepreneurship with social and ecological gains as well as economic ones—can significantly address societal and environmental challenges, however, it is not clear how policy can support it. The authors develop a policy framework for sustainable entrepreneurship, using...... impact/performance; and innovating government. Contributions to entrepreneurship policy literature include measuring impact/performance and open policy innovation for entrepreneurship policy. Contributions to sustainability policy literature include empowering individuals as entrepreneurs and not just...... consumers. A sustainable entrepreneurship framework is developed. A method for crowdsourcing policy innovations is outlined....

  14. Updated Colombian Seismic Hazard Map

    Science.gov (United States)

    Eraso, J.; Arcila, M.; Romero, J.; Dimate, C.; Bermúdez, M. L.; Alvarado, C.

    2013-05-01

    possible to determinate environments and scenarios where the seismic hazard is a function of distance and magnitude and also the principal seismic sources that contribute to the seismic hazard at each site (dissagregation). This project was conducted by the Servicio Geológico Colombiano (Colombian Geological Survey) and the Universidad Nacional de Colombia (National University of Colombia), with the collaboration of national and foreign experts and the National System of Prevention and Attention of Disaster (SNPAD). It is important to stand out that this new seismic hazard map was used in the updated national building code (NSR-10). A new process is ongoing in order to improve and present the Seismic Hazard Map in terms of intensity. This require new knowledge in site effects, in both local and regional scales, checking the existing and develop new acceleration to intensity relationships, in order to obtain results more understandable and useful for a wider range of users, not only in the engineering field, but also all the risk assessment and management institutions, research and general community.

  15. Fast reactor database. 2006 update

    International Nuclear Information System (INIS)

    2006-12-01

    plants. The recurring themes are the selection and summary of the data associated with the choice of coolant, fuel and structural materials, reduction of the steel weight, simplification of the plant design/layout, other important fast reactor design issues, and how to solve these problems. In the field of fast reactor design and operational data, the last reference document published by the IAEA was the 1996 Fast Reactor Database (IAEA-TECDOC-866). Since its publication, quite a lot has happened: the construction of two new reactors has been launched, and conceptual/design studies were initiated for various fast reactors, e.g. the Japanese JSFR-1500 and the Russian BN-1800 (both cooled by sodium), as well as for a wholly new line of LMFR concepts - modular reactors cooled by sodium and by lead-bismuth alloy, and prototype and demonstration commercial size fast reactors cooled by lead. The data were produced by the IAEA's Technical Working Group on Fast Reactors (TWG-FR). For many of the TWG-FR Member States there is a significant history of fast reactor development, often extending over a period of 40+ years. The new and updated information on LMFR, which are in operation, under construction or development, has been prepared with contributions from China, India, Japan, Republic of Korea and the Russian Federation. The information contained in IAEA-TECDOC-866, produced by France, Germany, Italy, the UK and the USA, was included in the present report with some modification taking into account last events

  16. Country policy profile - Slovakia. April 2015

    International Nuclear Information System (INIS)

    2015-04-01

    According to the Directive 2009/28/EC of the European Parliament and of the European Council on the promotion of the use of energy from renewable sources the target for the share of energy from renewable sources in gross final energy consumption in the year 2020 for Slovakia is 14%, whereas in 2012 it reached 10,6%. The Slovak Republic uses a feed-in tariff system in the promotion of renewable electricity. Energy companies are obliged to purchase and pay for electricity transmitted to the grid. Renewable energy utilization is furthermore incentivised in a form of exemption from excise tax. Currently the Slovak Republic conducts a professional training programme for RES-installers and there are RES-H building obligations. This report monitors the policy changes after the release of the 2013 Progress Report for Slovakia and is regularly updated. In recent months, no significant change in country's RES policies has been reported

  17. Country policy profile - Slovakia. December 2015

    International Nuclear Information System (INIS)

    2015-12-01

    According to the Directive 2009/28/EC of the European Parliament and of the European Council on the promotion of the use of energy from renewable sources the target for the share of energy from renewable sources in gross final energy consumption in the year 2020 for Slovakia is 14%, whereas in 2012 it reached 10,6%. The Slovak Republic uses a feed-in tariff system in the promotion of renewable electricity. Energy companies are obliged to purchase and pay for electricity transmitted to the grid. Renewable energy utilization is furthermore incentivised in a form of exemption from excise tax. Currently the Slovak Republic conducts a professional training programme for RES-installers and there are RES-H building obligations. This report monitors the policy changes after the release of the 2013 Progress Report for Slovakia and is regularly updated. In recent months, no significant change in country's RES policies has been reported

  18. A Provenance Tracking Model for Data Updates

    Directory of Open Access Journals (Sweden)

    Gabriel Ciobanu

    2012-08-01

    Full Text Available For data-centric systems, provenance tracking is particularly important when the system is open and decentralised, such as the Web of Linked Data. In this paper, a concise but expressive calculus which models data updates is presented. The calculus is used to provide an operational semantics for a system where data and updates interact concurrently. The operational semantics of the calculus also tracks the provenance of data with respect to updates. This provides a new formal semantics extending provenance diagrams which takes into account the execution of processes in a concurrent setting. Moreover, a sound and complete model for the calculus based on ideals of series-parallel DAGs is provided. The notion of provenance introduced can be used as a subjective indicator of the quality of data in concurrent interacting systems.

  19. Clean Coal Technology Programs: Program Update 2009

    Energy Technology Data Exchange (ETDEWEB)

    None

    2009-10-01

    The purpose of the Clean Coal Technology Programs: Program Update 2009 is to provide an updated status of the U.S. Department of Energy (DOE) commercial-scale demonstrations of clean coal technologies (CCT). These demonstrations have been performed under the Clean Coal Technology Demonstration Program (CCTDP), the Power Plant Improvement Initiative (PPII), and the Clean Coal Power Initiative (CCPI). Program Update 2009 provides: (1) a discussion of the role of clean coal technology demonstrations in improving the nation’s energy security and reliability, while protecting the environment using the nation’s most abundant energy resource—coal; (2) a summary of the funding and costs of the demonstrations; and (3) an overview of the technologies being demonstrated, along with fact sheets for projects that are active, recently completed, or recently discontinued.

  20. Model parameter updating using Bayesian networks

    Energy Technology Data Exchange (ETDEWEB)

    Treml, C. A. (Christine A.); Ross, Timothy J.

    2004-01-01

    This paper outlines a model parameter updating technique for a new method of model validation using a modified model reference adaptive control (MRAC) framework with Bayesian Networks (BNs). The model parameter updating within this method is generic in the sense that the model/simulation to be validated is treated as a black box. It must have updateable parameters to which its outputs are sensitive, and those outputs must have metrics that can be compared to that of the model reference, i.e., experimental data. Furthermore, no assumptions are made about the statistics of the model parameter uncertainty, only upper and lower bounds need to be specified. This method is designed for situations where a model is not intended to predict a complete point-by-point time domain description of the item/system behavior; rather, there are specific points, features, or events of interest that need to be predicted. These specific points are compared to the model reference derived from actual experimental data. The logic for updating the model parameters to match the model reference is formed via a BN. The nodes of this BN consist of updateable model input parameters and the specific output values or features of interest. Each time the model is executed, the input/output pairs are used to adapt the conditional probabilities of the BN. Each iteration further refines the inferred model parameters to produce the desired model output. After parameter updating is complete and model inputs are inferred, reliabilities for the model output are supplied. Finally, this method is applied to a simulation of a resonance control cooling system for a prototype coupled cavity linac. The results are compared to experimental data.

  1. Indoor Spatial Updating with Reduced Visual Information.

    Directory of Open Access Journals (Sweden)

    Gordon E Legge

    Full Text Available Spatial updating refers to the ability to keep track of position and orientation while moving through an environment. People with impaired vision may be less accurate in spatial updating with adverse consequences for indoor navigation. In this study, we asked how artificial restrictions on visual acuity and field size affect spatial updating, and also judgments of the size of rooms.Normally sighted young adults were tested with artificial restriction of acuity in Mild Blur (Snellen 20/135 and Severe Blur (Snellen 20/900 conditions, and a Narrow Field (8° condition. The subjects estimated the dimensions of seven rectangular rooms with and without these visual restrictions. They were also guided along three-segment paths in the rooms. At the end of each path, they were asked to estimate the distance and direction to the starting location. In Experiment 1, the subjects walked along the path. In Experiment 2, they were pushed in a wheelchair to determine if reduced proprioceptive input would result in poorer spatial updating.With unrestricted vision, mean Weber fractions for room-size estimates were near 20%. Severe Blur but not Mild Blur yielded larger errors in room-size judgments. The Narrow Field was associated with increased error, but less than with Severe Blur. There was no effect of visual restriction on estimates of distance back to the starting location, and only Severe Blur yielded larger errors in the direction estimates. Contrary to expectation, the wheelchair subjects did not exhibit poorer updating performance than the walking subjects, nor did they show greater dependence on visual condition.If our results generalize to people with low vision, severe deficits in acuity or field will adversely affect the ability to judge the size of indoor spaces, but updating of position and orientation may be less affected by visual impairment.

  2. State energy-price system: 1981 update

    Energy Technology Data Exchange (ETDEWEB)

    Fang, J.M.; Imhoff, K.L.; Hood, L.J.

    1983-08-01

    This report updates the State Energy Price Data System (STEPS) to include state-level energy prices by fuel and by end-use sectors for 1981. Both physical unit prices and Btu prices are presented. Basic documentation of the data base remains generally the same as in the original report: State Energy Price System; Volume 1: Overview and Technical Documentation (DOE/NBB-0029 Volume 1 of 2, November 1982). The present report documents only the changes in procedures necessitated by the update to 1981 and the corrections to the basic documentation.

  3. Summary Analysis: Hanford Site Composite Analysis Update

    Energy Technology Data Exchange (ETDEWEB)

    Nichols, W. E. [CH2M HILL Plateau Remediation Company, Richland, WA (United States); Lehman, L. L. [CH2M HILL Plateau Remediation Company, Richland, WA (United States)

    2017-06-05

    The Hanford Site’s currently maintained Composite Analysis, originally completed in 1998, requires an update. A previous update effort was undertaken by the U.S. Department of Energy (DOE) in 2001-2005, but was ended before completion to allow the Tank Closure & Waste Management Environmental Impact Statement (TC&WM EIS) (DOE/EIS-0391) to be prepared without potential for conflicting sitewide models. This EIS was issued in 2012, and the deferral was ended with guidance in memorandum “Modeling to Support Regulatory Decision Making at Hanford” (Williams, 2012) provided with the aim of ensuring subsequent modeling is consistent with the EIS.

  4. Updating radiation protection regulations in Egypt

    International Nuclear Information System (INIS)

    Gomaa, M.A.; El-Naggar, A.M.

    1996-01-01

    The aim of this treatise is to present -the rational steps taken in the process of updating the Radiation Protection Regulations in Egypt. The contents of the review will include a historical synopsis, and the current state of art regarding competent authorities. Furthermore, the various committees formed with responsibilities for specific issues are indicated, including the role of the Ministry of Health (MOH), and that of the Atomic Energy Authority (AEA). Finally, the efforts made towards updating the radiation Protection Regulations in Egypt are highlighted. (author)

  5. Policy and Strategies for Environmental Remediation

    International Nuclear Information System (INIS)

    2015-01-01

    out in the policy statement. For its formulation, detailed information is needed on the current situation in the country (organizational, technical and legislative). The technical solutions proposed for the remediation of sites in the country need to be politically, technically and economically feasible. When selecting a set of technological procedures, an appropriate end point must be identified, usually a suitable end state. The steps in formulating and implementing the strategy include selecting the technical procedures, allocating the responsibility for implementing the identified procedures, establishing supervisory mechanisms and developing implementation plans. The policy and strategies may need to be updated because of new national circumstances (legislative changes, plans for new nuclear facilities), new international agreements and/or experience obtained with the original policy and strategies. The lead in making changes is to be taken by the body responsible for the initial formulation of the policy (government) and strategy, but all relevant parties in the country are to be involved and consulted in this process

  6. How do we update faces? Effects of gaze direction and facial expressions on working memory updating

    Directory of Open Access Journals (Sweden)

    Caterina eArtuso

    2012-09-01

    Full Text Available The aim of the study was to investigate how the biological binding between different facial dimensions, and their social and communicative relevance, may impact updating processes in working memory (WM. We focused on WM updating because it plays a key role in ongoing processing. Gaze direction and facial expression are crucial and changeable components of face processing. Direct gaze enhances the processing of approach-oriented facial emotional expressions (e.g. joy, while averted gaze enhances the processing of avoidance-oriented facial emotional expressions (e.g. fear. Thus, the way in which these two facial dimensions are combined communicates to the observer important behavioral and social information. Updating of these two facial dimensions and their bindings has not been investigated before, despite the fact that they provide a piece of social information essential for building and maintaining an internal ongoing representation of our social environment. In Experiment 1 we created a task in which the binding between gaze direction and facial expression was manipulated: high binding conditions (e.g. joy-direct gaze were compared to low binding conditions (e.g. joy-averted gaze. Participants had to study and update continuously a number of faces, displaying different bindings between the two dimensions. In Experiment 2 we tested whether updating was affected by the social and communicative value of the facial dimension binding; to this end, we manipulated bindings between eye and hair color, two less communicative facial dimensions. Two new results emerged. First, faster response times were found in updating combinations of facial dimensions highly bound together. Second, our data showed that the ease of the ongoing updating processing varied depending on the communicative meaning of the binding that had to be updated. The results are discussed with reference to the role of WM updating in social cognition and appraisal processes.

  7. How do we update faces? Effects of gaze direction and facial expressions on working memory updating.

    Science.gov (United States)

    Artuso, Caterina; Palladino, Paola; Ricciardelli, Paola

    2012-01-01

    The aim of the study was to investigate how the biological binding between different facial dimensions, and their social and communicative relevance, may impact updating processes in working memory (WM). We focused on WM updating because it plays a key role in ongoing processing. Gaze direction and facial expression are crucial and changeable components of face processing. Direct gaze enhances the processing of approach-oriented facial emotional expressions (e.g., joy), while averted gaze enhances the processing of avoidance-oriented facial emotional expressions (e.g., fear). Thus, the way in which these two facial dimensions are combined communicates to the observer important behavioral and social information. Updating of these two facial dimensions and their bindings has not been investigated before, despite the fact that they provide a piece of social information essential for building and maintaining an internal ongoing representation of our social environment. In Experiment 1 we created a task in which the binding between gaze direction and facial expression was manipulated: high binding conditions (e.g., joy-direct gaze) were compared to low binding conditions (e.g., joy-averted gaze). Participants had to study and update continuously a number of faces, displaying different bindings between the two dimensions. In Experiment 2 we tested whether updating was affected by the social and communicative value of the facial dimension binding; to this end, we manipulated bindings between eye and hair color, two less communicative facial dimensions. Two new results emerged. First, faster response times were found in updating combinations of facial dimensions highly bound together. Second, our data showed that the ease of the ongoing updating processing varied depending on the communicative meaning of the binding that had to be updated. The results are discussed with reference to the role of WM updating in social cognition and appraisal processes.

  8. Corporate Language Policies

    DEFF Research Database (Denmark)

    Sanden, Guro Refsum

    This paper offers a review of literature dealing with language policies in general and corporate language policies in particular. Based on a discussion of various definitions of these concepts within two research traditions, i.e. sociolinguistics and international management, a three......-level definition of corporate language policies is presented, emphasising that a corporate language policy is a context-specific policy about language use. The three-level definition is based on the argument that in order to acquire a complete understanding of what corporate language policies involve, one needs...... to consider three progressive questions; 1) what is a policy? 2) what is a language policy?, and ultimately, 3) what is a corporate language policy?...

  9. Corporate Language Policies

    DEFF Research Database (Denmark)

    Sanden, Guro Refsum

    2015-01-01

    This paper offers a review of literature dealing with language policies in general and corporate language policies in particular. Based on a discussion of various definitions of these concepts within two research traditions, i.e. sociolinguistics and international management, a three......-level definition of corporate language policies is presented, emphasising that a corporate language policy is a context-specific policy about language use. The three-level definition is based on the argument that in order to acquire a complete understanding of what corporate language policies involve, one needs...... to consider three progressive questions; 1) what is a policy? 2) what is a language policy?, and ultimately, 3) what is a corporate language policy?...

  10. Update on an Interstellar Asteroid

    Science.gov (United States)

    Kohler, Susanna

    2018-01-01

    Whats the news coming from the research world on the interstellar asteroid visitor, asteroid 1I/Oumuamua? Read on for an update from a few of the latest studies.What is Oumuamua?In lateOctober2017, the discovery of minor planet 1I/Oumuamua was announced. This body which researchers first labeled asa comet and later revised to an asteroid had just zipped around the Sun and was already in the process of speeding away whenwe trained our telescopes on it. Its trajectory, however, marked it as being a visitor from outside our solar system: the first knownvisitorof its kind.Since Oumuamuasdiscovery, scientists have been gathering as many observations of this bodyas possible before it vanishes into the distance. Simultaneously, theorists have leapt at the opportunity to explain its presence and the implications its passage has on our understanding of our surroundings. Here we present just a few of the latest studies that have been published on this first detected interstellar asteroid including several timelystudies published in our new journal, Research Notes of the AAS.The galactic velocity of Oumuamua does not coincide with any of the nearest stars to us. [Mamajek 2018]Where Did Oumuamua Come From?Are we sure Oumuamua didnt originate in our solar system andget scattered into a weird orbit? Jason Wright (The Pennsylvania State University) demonstrates via a series of calculations that no known solar system body could have scattered Oumuamua onto its current orbit nor could any stillunknown object bound to our solar system.Eric Mamajek (Caltech and University of Rochester) showsthat thekinematics of Oumuamua areconsistent with what we might expect of interstellar field objects, though he argues that its kinematics suggest its unlikely to have originated from many of the neareststellar systems.What AreOumuamuas Properties?Oumuamuas light curve. [Bannister et al. 2017]A team of University of Maryland scientists led by Matthew Knight captured a light curve of Oumuamua using

  11. Environmental development plan for transportation programs: FY80 update

    Energy Technology Data Exchange (ETDEWEB)

    Saricks, C.L.; Singh, M.K.; Bernard, M.J. III; Bevilacqua, O.M.

    1980-09-01

    This is the second annual update of the environmental development plan (EDP) for transportation programs. It has been prepared as a cooperative effort of the Assistant Secretaries for Conservation and Solar Energy (ASCS) Office of Transportation Programs (CS/TP) and the Environment (ASEV) Office of Environmental Assessments. EDPs identify the ecosystem, resource, physical environment, health, safety, socioeconomic, and environmental control concerns associated with DOE programs. The programs include the research, development, demonstration, and assessment (RDD and A) of 14 transportation technologies and several strategy implementation projects. This EDP update presents a research and assessment plan for resolving any potentially adverse environmental concerns arising from these programs. The EDP process provides a framework for: incorporating environmental concerns into CS/TP planning and decision processes early to ensure they are assigned the same importance as technological, fiscal, and institutional concerns in decision making; resolving environmental concerns concurrently with energy technology and strategy development; and providing a research schedule that mitigates adverse environmental effects through sound technological design or policy analysis. This EDP also describes the status of each environmental concern and the plan for its resolution. Much of ongoing DOE reseirch and technology development is aimed at resolving concerns identified in this EDP. Each EDP is intended to be so comprehensive that no concerns escape notice. Care is taken to include any CS/TP action that may eventually require an Environmental Impact Statement. Because technology demonstration and commercialization tend to raise more environmental concerns than other portions of the transportation program, most of this EDP addresses these concerns.

  12. Collaborative pharmacy practice: an update

    Directory of Open Access Journals (Sweden)

    Law AV

    2013-06-01

    Full Text Available Anandi V Law, Eric K Gupta, Micah Hata, Karl M Hess, Roger S Klotz, Quang A Le, Emmanuelle Schwartzman, Bik-Wai Bilvick Tai Department of Pharmacy Practice and Administration, College of Pharmacy, Western University of Health Sciences, Pomona, CA, USA Abstract: Collaborative practice among health professionals is slowly coming of age, given the global focus on efficiency and effectiveness of care to achieve positive patient outcomes and to reduce the economic burden of fragmented care. Collaborative pharmacy practice (CPP is accordingly evolving within different models including: disease management, medication therapy management, patient centered medical home, and accountable care organizations. Pharmacist roles in these models relate to drug therapy management and include therapy introduction, adjustment, or discontinuation, patient counseling and education, and identification, resolution, and prevention of problems leading to drug interactions and adverse reactions. Most forms of CPP occur with physicians in various settings. Collaborative practice agreements exist in many states in the US and are mentioned in the International Pharmaceutical Federation policy statement. Impetus for CPP comes from health system and economic concerns, as well as from a regulatory push. There are positive examples in community, ambulatory care, and inpatient settings that have well documented protocols, indicators of care, and measurement and reporting of clinical, economic, and patient reported outcomes; however, implementation of the practice is still not widespread. Conceptual and implementation challenges include health professional training, attitudes, confidence and comfort levels, power and communication issues, logistic barriers of time, workload, proximity, resistance to establish and adopt regulations, and importantly, payment models. Some of the attitudinal and perceptual challenges can be mitigated by incorporation of interprofessional concepts and

  13. Developing and implementing an oral care policy and assessment tool.

    LENUS (Irish Health Repository)

    Stout, Michelle

    2012-01-09

    Oral hygiene is an essential aspect of nursing care. Poor oral care results in patients experiencing pain and discomfort, puts individuals at risk of nutritional deficiency and infection, and has an adverse effect on quality of life. This article describes how an oral care policy and assessment tool were updated to ensure the implementation of evidence-based practice at one hospital in the Republic of Ireland.

  14. Streamlining Policy Creation in Policy Frameworks

    NARCIS (Netherlands)

    M.A. Hills (Mark); N. Martí-Oliet; M. Palomino

    2012-01-01

    textabstract{\\it Policy frameworks} provide a technique for improving reuse in program analysis: the same language frontend, and a core analysis semantics, can be shared among multiple analysis policies for the same language, while analysis domains (such as units of measurement) can be shared among

  15. Economic and Policy Review: Editorial Policies

    African Journals Online (AJOL)

    ... and economic environment in which they operate and work. EPR enlists experts in public policy, business, economic theory and practice to express their thoughts and views in the most influential way possible on economic policy and direction of government and the Nigerian economy in the short, medium and long terms.

  16. Fitness for duty in the nuclear industry: Update of the technical issues 1996

    Energy Technology Data Exchange (ETDEWEB)

    Durbin, N.; Grant, T. [eds.] [Battelle Seattle Research Center, WA (United States)

    1996-05-01

    The purpose of this report is to provide an update of information on the technical issues surrounding the creation, implementation, and maintenance of fitness-for-duty (FFD) policies and programs. It has been prepared as a resource for Nuclear Regulatory Commission (NRC) and nuclear power plant personnel who deal with FFD programs. It contains a general overview and update on the technical issues that the NRC considered prior to the publication of its original FFD rule and the revisions to that rule (presented in earlier NUREG/CRs). It also includes chapters that address issues about which there is growing concern and/or about which there have been substantial changes since NUREG/CR-5784 was published. Although this report is intended to support the NRC`s rule making on fitness for duty, the conclusions of the authors of this report are their own and do not necessarily represent the opinions of the NRC.

  17. Fitness for duty in the nuclear industry: Update of the technical issues 1996

    International Nuclear Information System (INIS)

    Durbin, N.; Grant, T.

    1996-05-01

    The purpose of this report is to provide an update of information on the technical issues surrounding the creation, implementation, and maintenance of fitness-for-duty (FFD) policies and programs. It has been prepared as a resource for Nuclear Regulatory Commission (NRC) and nuclear power plant personnel who deal with FFD programs. It contains a general overview and update on the technical issues that the NRC considered prior to the publication of its original FFD rule and the revisions to that rule (presented in earlier NUREG/CRs). It also includes chapters that address issues about which there is growing concern and/or about which there have been substantial changes since NUREG/CR-5784 was published. Although this report is intended to support the NRC's rule making on fitness for duty, the conclusions of the authors of this report are their own and do not necessarily represent the opinions of the NRC

  18. Developing policies and procedures.

    Science.gov (United States)

    Randolph, Susan A

    2006-11-01

    The development of policies and procedures is an integral part of the occupational health nurse's role. Policies and procedures serve as the foundation for the occupational health service and are based on its vision, mission, culture, and values. The design and layout selected for the policies and procedures should be simple, consistent, and easy to use. The same format should be used for all existing and new policies and procedures. Policies and procedures should be reviewed periodically based on a specified time frame (i.e., annually). However, some policies may require a more frequent review if they involve rapidly changing external standards, ethical issues, or emerging exposures.

  19. The Policy Design Effect

    DEFF Research Database (Denmark)

    Hedegaard, Troels Fage

    2014-01-01

    Public and individual support for a policy is affected by how it is designed – that is, how eligibility is determined. This results in universal policies being more popular than contributions-based policies, which in turn enjoy more public support than the selective kind. The literature on welfare...... benefits in Denmark shows a large impact on attitudes from being proximate to recipients under selective policies, little or no impact from universal policies and a pattern that falls in-between for the contributions-based policy. This article thus provides micro-level evidence for the different impacts...

  20. [Healthy pharmaceutical policy].

    Science.gov (United States)

    González Pier, Eduardo

    2008-01-01

    Today, the pharmaceutical industry is experiencing a profound transition. Globalization and technological advancement represent the principal pressures for change in the market, where it is increasingly more difficult for this type of industry to efficiently recoup the growing cost of innovation. Mexico needs to analyze the policy implications of these change factors and promote, in the pharmaceutical market, policies that maximize health gains on invested resources. Pharmaceutical policy offers a rare example for a complementary approach between a sound health policy and an efficient economic policy; that is, a "healthy pharmaceutical policy."

  1. Innovation policies for tourism

    DEFF Research Database (Denmark)

    Hjalager, Anne-Mette

    2012-01-01

    The nature, extent, and implications of innovation in tourism are increasingly investigated in academic research, but the policies that affect these transformations in the industry and at tourism destinations are not equally well conceptualised theoretically or analysed empirically. The purpose...... of this article is, in an analysis of the literature, to interpret the rationale behind innovation policy, and to explain the persisting challenges related to acquisition of an informed foundation for policies based upon quantitative and qualitative inquiries. Observed in a historical perspective, innovation...... framework of policy instruments for innovation in tourism. New generations of policies instigate a mainstreaming of the innovation agenda in ways that proceed beyond the traditional policy concepts....

  2. [Energy policy rather than climate policy].

    Science.gov (United States)

    Kroonenberg, Salomon B

    2009-01-01

    Energy policy and climate policy are two different issues and should not be treated as if they were the same. Whether the climate gets warmer or colder, saving energy and developing sustainable forms of energy production remain of paramount importance because fossil hydrocarbons are likely to be exhausted soon. But climate policy is a fallacy: it is human arrogance to think we can control the climate by reducing emissions and by storing CO2 underground. In spite of rising CO2 levels, the climate has cooled down slightly over the past decade. Since the International Panel on Climate Change (IPCC) did not predict this, it is questionable whether they can reliably predict warming. Other factors such as solar activity are probably more important for climate than greenhouse gases. The danger of coupling energy policy to climate policy is evident: if the climate cools down, people will lose belief in the greenhouse effect and therefore also lose interest in saving energy.

  3. 2016 updated MASCC/ESMO consensus recommendations

    DEFF Research Database (Denmark)

    Roila, Fausto; Warr, David; Hesketh, Paul J

    2017-01-01

    PURPOSE: An update of the recommendations for the prophylaxis of acute and delayed emesis induced by moderately emetogenic chemotherapy published after the last MASCC/ESMO antiemetic consensus conference in 2009 has been carried out. METHODS: A systematic literature search using PubMed from Janua...

  4. American Automobile and Light Truck Statistics Update

    Science.gov (United States)

    Feldman, Bernard J.

    2014-01-01

    Given that transportation is an essential topic in any Physics and Society or Energy course, it is necessary to have useful statistics on transportation in order to have a reasoned discussion on this topic. And a major component of the transportation picture is the automobile. This paper presents updated transportation statistics for American…

  5. Invasive Species Science Update (No. 1)

    Science.gov (United States)

    Mee-Sook Kim; Jack Butler

    2008-01-01

    This electronic newsletter (Invasive Species Science Update) is published by the Rocky Mountain Research Station (RMRS) Cross-Program, Interdisciplinary Project team on Invasive Species. This newsletter will be published 3 times per year and is intended to enhance communication among RMRS scientists, wildland managers, other partners, stakeholders, and customers about...

  6. Invasive Species Science Update (No. 4)

    Science.gov (United States)

    Ned B. Klopfenstein; Brian W. Geils

    2010-01-01

    The fourth issue of Invasive Species Science Update has finally arrived. This newsletter has no set publication schedule, but our intent is to deliver invasive species information on a timely basis. The RMRS Invasive Species Working Group (ISWG) has been reorganized and recharged. General information on the ISWG is presented in a publication by Butler and others (2009...

  7. Invasive Species Science Update (No. 7)

    Science.gov (United States)

    Dean Pearson; Yvette Ortega; Jack Butler

    2014-01-01

    Invasive Species Science Updates are designed to keep managers and other users up-to-date with recently completed and ongoing research by RMRS scientists, as well as highlight breaking news related to invasive species issues. The newsletter is produced by the RMRS Invasive Species Working Group (ISWG), which is a core group of scientists who volunteer to coordinate...

  8. Invasive Species Science Update (No. 5)

    Science.gov (United States)

    Dean Pearson; Yvette Ortega

    2011-01-01

    Welcome to the fifth issue of the Rocky Mountain Research Station's (RMRS) Invasive Species Science Update. The newsletter is produced by the RMRS Invasive Species Working Group (ISWG), which is a core group of scientists who volunteer to coordinate outreach of RMRS invasive species science to managers and the public. After publishing the past four newsletters, we...

  9. Invasive Species Science Update (No. 8)

    Science.gov (United States)

    Dean Pearson; Yvette Ortega; Jack Butler

    2015-01-01

    Invasive Species Science Updates are designed to keep managers and other users up-to-date with recently completed and ongoing research by RMRS scientists, as well as highlight breaking news related to invasive species issues. The newsletter is produced by the RMRS Invasive Species Working Group (ISWG), which is a core group of scientists who volunteer to coordinate...

  10. Invasive Species Science Update (No. 6)

    Science.gov (United States)

    Paula Fornwalt

    2013-01-01

    The sixth issue of the Rocky Mountain Research Station's (RMRS) Invasive Species Science Update is now complete. Published approximately once per year, this newsletter keeps managers and other users up-to-date with recently completed and ongoing research by RMRS scientists, and covers breaking news related to invasive species issues. The newsletter is produced by...

  11. Traffic Flow Management: Data Mining Update

    Science.gov (United States)

    Grabbe, Shon R.

    2012-01-01

    This presentation provides an update on recent data mining efforts that have been designed to (1) identify like/similar days in the national airspace system, (2) cluster/aggregate national-level rerouting data and (3) apply machine learning techniques to predict when Ground Delay Programs are required at a weather-impacted airport

  12. Update on phototherapy in jaundiced neonates

    DEFF Research Database (Denmark)

    Ebbesen, Finn; Hansen, Thor Willy Ruud; Maisels, M Jeffrey

    2017-01-01

    is the current treatment of choice. OBJECTIVE: To present an update on the most important issues involved in phototherapy for jaundiced infants. RESULTS: Light absorption by bilirubin in the skin transforms the native Z,Z-bilirubin to conformational photoisomers Z,E-bilirubin and E,Z-bilirubin and structural...

  13. [WWW.2CHEAT.COM] Update

    Science.gov (United States)

    Rooks, Clay D.

    2006-01-01

    This paper is an updated presentation on the subject of cheating and plagiarism via the World Wide Web. In a few hours searching the Internet, the author found even more "cheat" sites than in 1998 that offered not only all types of term and research papers, but college admission letters, reviews, case studies, even dissertations as well. Most now…

  14. 77 FR 13198 - Product List Update

    Science.gov (United States)

    2012-03-06

    ... Agreements Domestic Outbound International Part C--Glossary of Terms and Conditions [Reserved] Part D... rule. SUMMARY: The Commission is updating the market dominant and competitive product lists. This..., CP2012-12 and CP2012-13); Global Plus 2C (MC2012-5, CP2012-10 and CP2012-11); and Inbound Market Dominant...

  15. The 2005 RPA timber assessment update.

    Science.gov (United States)

    Richard W. Haynes; Darius M. Adams; Ralph J. Alig; Peter J. Ince; John R. Mills; Xiaoping. Zhou

    2007-01-01

    This update reports changes in the Nation's timber resource since the Analysis of the Timber Situation in the United States was completed in 2003. Prospective trends in demands for and supplies of timber, and the factors that affect these trends are examined. These trends include changes in the U.S. economy, increased salvage of British Columbia beetle-killed...

  16. Update of the exploratory report Acrolein

    NARCIS (Netherlands)

    Slooff W; Bont PFH; Janus JA; Pronk MEJ; Ros JPM; ECO; PPCbv; ACT; LAE

    1994-01-01

    The report is an update of the exploratory report acrolein (Slooff et al., 1991) that served as a basis for the discussion during the exploratory meeting on acrolein in March 1992. The meeting supported the conclusion that priority should be given to the compartment air and to the risks to humans.

  17. Kalman filter to update forest cover estimates

    Science.gov (United States)

    Raymond L. Czaplewski

    1990-01-01

    The Kalman filter is a statistical estimator that combines a time-series of independent estimates, using a prediction model that describes expected changes in the state of a system over time. An expensive inventory can be updated using model predictions that are adjusted with more recent, but less expensive and precise, monitoring data. The concepts of the Kalman...

  18. Kingdom of Morocco : Financial Sector Assessment Update

    OpenAIRE

    World Bank

    2008-01-01

    A joint World Bank and International Monetary Fund team visited Morocco in November 2007 at the request of the authorities to update the analysis and recommendations made in the framework of the Financial Sector Assessment Program (FSAP) in 2002 and to assist the authorities in preparing their medium-term strategy for modernizing financial intermediation in Morocco. This Financial Sector A...

  19. An update to the Surface Ocean CO

    NARCIS (Netherlands)

    Bakker, D.C.E.; de Baar, H.J.W.; van heuven, S.

    2014-01-01

    The Surface Ocean CO2 Atlas (SOCAT), an activity of the international marine carbon research community, provides access to synthesis and gridded fCO2 (fugacity of carbon dioxide) products for the surface oceans. Version 2 of SOCAT is an update of the previous release (version

  20. Updated Abraham solvation parameters for polychlorinated biphenyls

    NARCIS (Netherlands)

    van Noort, P.C.M.; Haftka, J.J.H.; Parsons, J.R.

    2010-01-01

    This study shows that the recently published polychlorinated biphenyl (PCB) Abraham solvation parameters predict PCB air−n-hexadecane and n-octanol−water partition coefficients very poorly, especially for highly ortho-chlorinated congeners. Therefore, an updated set of PCB solvation parameters was