Degraded character recognition based on gradient pattern

Science.gov (United States)

Babu, D. R. Ramesh; Ravishankar, M.; Kumar, Manish; Wadera, Kevin; Raj, Aakash

2010-02-01

Degraded character recognition is a challenging problem in the field of Optical Character Recognition (OCR). The performance of an optical character recognition depends upon printed quality of the input documents. Many OCRs have been designed which correctly identifies the fine printed documents. But, very few reported work has been found on the recognition of the degraded documents. The efficiency of the OCRs system decreases if the input image is degraded. In this paper, a novel approach based on gradient pattern for recognizing degraded printed character is proposed. The approach makes use of gradient pattern of an individual character for recognition. Experiments were conducted on character image that is either digitally written or a degraded character extracted from historical documents and the results are found to be satisfactory.

Accelerated gradient methods for total-variation-based CT image reconstruction

Energy Technology Data Exchange (ETDEWEB)

Joergensen, Jakob H.; Hansen, Per Christian [Technical Univ. of Denmark, Lyngby (Denmark). Dept. of Informatics and Mathematical Modeling; Jensen, Tobias L.; Jensen, Soeren H. [Aalborg Univ. (Denmark). Dept. of Electronic Systems; Sidky, Emil Y.; Pan, Xiaochuan [Chicago Univ., Chicago, IL (United States). Dept. of Radiology

2011-07-01

Total-variation (TV)-based CT image reconstruction has shown experimentally to be capable of producing accurate reconstructions from sparse-view data. In particular TV-based reconstruction is well suited for images with piecewise nearly constant regions. Computationally, however, TV-based reconstruction is demanding, especially for 3D imaging, and the reconstruction from clinical data sets is far from being close to real-time. This is undesirable from a clinical perspective, and thus there is an incentive to accelerate the solution of the underlying optimization problem. The TV reconstruction can in principle be found by any optimization method, but in practice the large scale of the systems arising in CT image reconstruction preclude the use of memory-intensive methods such as Newton's method. The simple gradient method has much lower memory requirements, but exhibits prohibitively slow convergence. In the present work we address the question of how to reduce the number of gradient method iterations needed to achieve a high-accuracy TV reconstruction. We consider the use of two accelerated gradient-based methods, GPBB and UPN, to solve the 3D-TV minimization problem in CT image reconstruction. The former incorporates several heuristics from the optimization literature such as Barzilai-Borwein (BB) step size selection and nonmonotone line search. The latter uses a cleverly chosen sequence of auxiliary points to achieve a better convergence rate. The methods are memory efficient and equipped with a stopping criterion to ensure that the TV reconstruction has indeed been found. An implementation of the methods (in C with interface to Matlab) is available for download from http://www2.imm.dtu.dk/~pch/TVReg/. We compare the proposed methods with the standard gradient method, applied to a 3D test problem with synthetic few-view data. We find experimentally that for realistic parameters the proposed methods significantly outperform the standard gradient method. (orig.)

A density gradient theory based method for surface tension calculations

DEFF Research Database (Denmark)

Liang, Xiaodong; Michelsen, Michael Locht; Kontogeorgis, Georgios

2016-01-01

The density gradient theory has been becoming a widely used framework for calculating surface tension, within which the same equation of state is used for the interface and bulk phases, because it is a theoretically sound, consistent and computationally affordable approach. Based on the observation...... that the optimal density path from the geometric mean density gradient theory passes the saddle point of the tangent plane distance to the bulk phases, we propose to estimate surface tension with an approximate density path profile that goes through this saddle point. The linear density gradient theory, which...... assumes linearly distributed densities between the two bulk phases, has also been investigated. Numerical problems do not occur with these density path profiles. These two approximation methods together with the full density gradient theory have been used to calculate the surface tension of various...

Gradient descent for robust kernel-based regression

Science.gov (United States)

Guo, Zheng-Chu; Hu, Ting; Shi, Lei

2018-06-01

In this paper, we study the gradient descent algorithm generated by a robust loss function over a reproducing kernel Hilbert space (RKHS). The loss function is defined by a windowing function G and a scale parameter σ, which can include a wide range of commonly used robust losses for regression. There is still a gap between theoretical analysis and optimization process of empirical risk minimization based on loss: the estimator needs to be global optimal in the theoretical analysis while the optimization method can not ensure the global optimality of its solutions. In this paper, we aim to fill this gap by developing a novel theoretical analysis on the performance of estimators generated by the gradient descent algorithm. We demonstrate that with an appropriately chosen scale parameter σ, the gradient update with early stopping rules can approximate the regression function. Our elegant error analysis can lead to convergence in the standard L 2 norm and the strong RKHS norm, both of which are optimal in the mini-max sense. We show that the scale parameter σ plays an important role in providing robustness as well as fast convergence. The numerical experiments implemented on synthetic examples and real data set also support our theoretical results.

Large Airborne Full Tensor Gradient Data Inversion Based on a Non-Monotone Gradient Method

Science.gov (United States)

Sun, Yong; Meng, Zhaohai; Li, Fengting

2018-03-01

Following the development of gravity gradiometer instrument technology, the full tensor gravity (FTG) data can be acquired on airborne and marine platforms. Large-scale geophysical data can be obtained using these methods, making such data sets a number of the "big data" category. Therefore, a fast and effective inversion method is developed to solve the large-scale FTG data inversion problem. Many algorithms are available to accelerate the FTG data inversion, such as conjugate gradient method. However, the conventional conjugate gradient method takes a long time to complete data processing. Thus, a fast and effective iterative algorithm is necessary to improve the utilization of FTG data. Generally, inversion processing is formulated by incorporating regularizing constraints, followed by the introduction of a non-monotone gradient-descent method to accelerate the convergence rate of FTG data inversion. Compared with the conventional gradient method, the steepest descent gradient algorithm, and the conjugate gradient algorithm, there are clear advantages of the non-monotone iterative gradient-descent algorithm. Simulated and field FTG data were applied to show the application value of this new fast inversion method.

Time-domain full waveform inversion using the gradient preconditioning based on transmitted waves energy

KAUST Repository

Zhang, Xiao-bo; Tan, Jun; Song, Peng; Li, Jin-shan; Xia, Dong-ming; Liu, Zhao-lun

2017-01-01

The gradient preconditioning approach based on seismic wave energy can effectively avoid the huge storage consumption in the gradient preconditioning algorithms based on Hessian matrices in time-domain full waveform inversion (FWI), but the accuracy

Adaptive dynamic programming for discrete-time linear quadratic regulation based on multirate generalised policy iteration

Science.gov (United States)

Chun, Tae Yoon; Lee, Jae Young; Park, Jin Bae; Choi, Yoon Ho

2018-06-01

In this paper, we propose two multirate generalised policy iteration (GPI) algorithms applied to discrete-time linear quadratic regulation problems. The proposed algorithms are extensions of the existing GPI algorithm that consists of the approximate policy evaluation and policy improvement steps. The two proposed schemes, named heuristic dynamic programming (HDP) and dual HDP (DHP), based on multirate GPI, use multi-step estimation (M-step Bellman equation) at the approximate policy evaluation step for estimating the value function and its gradient called costate, respectively. Then, we show that these two methods with the same update horizon can be considered equivalent in the iteration domain. Furthermore, monotonically increasing and decreasing convergences, so called value iteration (VI)-mode and policy iteration (PI)-mode convergences, are proved to hold for the proposed multirate GPIs. Further, general convergence properties in terms of eigenvalues are also studied. The data-driven online implementation methods for the proposed HDP and DHP are demonstrated and finally, we present the results of numerical simulations performed to verify the effectiveness of the proposed methods.

Microsphere-based gradient implants for osteochondral regeneration: a long-term study in sheep

Science.gov (United States)

Mohan, Neethu; Gupta, Vineet; Sridharan, Banu Priya; Mellott, Adam J; Easley, Jeremiah T; Palmer, Ross H; Galbraith, Richard A; Key, Vincent H; Berkland, Cory J; Detamore, Michael S

2015-01-01

Background: The microfracture technique for cartilage repair has limited ability to regenerate hyaline cartilage. Aim: The current study made a direct comparison between microfracture and an osteochondral approach with microsphere-based gradient plugs. Materials & methods: The PLGA-based scaffolds had opposing gradients of chondroitin sulfate and β-tricalcium phosphate. A 1-year repair study in sheep was conducted. Results: The repair tissues in the microfracture were mostly fibrous and had scattered fissures with degenerative changes. Cartilage regenerated with the gradient plugs had equal or superior mechanical properties; had lacunated cells and stable matrix as in hyaline cartilage. Conclusion: This first report of gradient scaffolds in a long-term, large animal, osteochondral defect demonstrated potential for equal or better cartilage repair than microfracture. PMID:26418471

Gradient-based reliability maps for ACM-based segmentation of hippocampus.

Science.gov (United States)

Zarpalas, Dimitrios; Gkontra, Polyxeni; Daras, Petros; Maglaveras, Nicos

2014-04-01

Automatic segmentation of deep brain structures, such as the hippocampus (HC), in MR images has attracted considerable scientific attention due to the widespread use of MRI and to the principal role of some structures in various mental disorders. In this literature, there exists a substantial amount of work relying on deformable models incorporating prior knowledge about structures' anatomy and shape information. However, shape priors capture global shape characteristics and thus fail to model boundaries of varying properties; HC boundaries present rich, poor, and missing gradient regions. On top of that, shape prior knowledge is blended with image information in the evolution process, through global weighting of the two terms, again neglecting the spatially varying boundary properties, causing segmentation faults. An innovative method is hereby presented that aims to achieve highly accurate HC segmentation in MR images, based on the modeling of boundary properties at each anatomical location and the inclusion of appropriate image information for each of those, within an active contour model framework. Hence, blending of image information and prior knowledge is based on a local weighting map, which mixes gradient information, regional and whole brain statistical information with a multi-atlas-based spatial distribution map of the structure's labels. Experimental results on three different datasets demonstrate the efficacy and accuracy of the proposed method.

Ionospheric forecasting model using fuzzy logic-based gradient descent method

Directory of Open Access Journals (Sweden)

D. Venkata Ratnam

2017-09-01

Full Text Available Space weather phenomena cause satellite to ground or satellite to aircraft transmission outages over the VHF to L-band frequency range, particularly in the low latitude region. Global Positioning System (GPS is primarily susceptible to this form of space weather. Faulty GPS signals are attributed to ionospheric error, which is a function of Total Electron Content (TEC. Importantly, precise forecasts of space weather conditions and appropriate hazard observant cautions required for ionospheric space weather observations are limited. In this paper, a fuzzy logic-based gradient descent method has been proposed to forecast the ionospheric TEC values. In this technique, membership functions have been tuned based on the gradient descent estimated values. The proposed algorithm has been tested with the TEC data of two geomagnetic storms in the low latitude station of KL University, Guntur, India (16.44°N, 80.62°E. It has been found that the gradient descent method performs well and the predicted TEC values are close to the original TEC measurements.

A gradient based algorithm to solve inverse plane bimodular problems of identification

Science.gov (United States)

Ran, Chunjiang; Yang, Haitian; Zhang, Guoqing

2018-02-01

This paper presents a gradient based algorithm to solve inverse plane bimodular problems of identifying constitutive parameters, including tensile/compressive moduli and tensile/compressive Poisson's ratios. For the forward bimodular problem, a FE tangent stiffness matrix is derived facilitating the implementation of gradient based algorithms, for the inverse bimodular problem of identification, a two-level sensitivity analysis based strategy is proposed. Numerical verification in term of accuracy and efficiency is provided, and the impacts of initial guess, number of measurement points, regional inhomogeneity, and noisy data on the identification are taken into accounts.

Evidence-based policy versus morality policy: the case of syringe access programs.

Science.gov (United States)

de Saxe Zerden, Lisa; O'Quinn, Erin; Davis, Corey

2015-01-01

Evidence-based practice (EBP) combines proven interventions with clinical experience, ethics, and client preferences to inform treatment and services. Although EBP is integrated into most aspects of social work and public health, at times EBP is at odds with social policy. In this article the authors explore the paradox of evidence-based policy using syringe access programs (SAP) as a case example, and review methods of bridging the gap between the emphasis on EBP and lack of evidence informing SAP policy. Analysis includes the overuse of morality policy and examines historical and current theories why this paradox exists. Action steps are highlighted for creating effective policy and opportunities for public health change. Strategies on reframing the problem and shifting target population focus to garner support for evidence-based policy change are included. This interdisciplinary understanding of the way in which these factors converge is a critical first step in moving beyond morality-based policy toward evidence-based policy.

Detection of ferromagnetic target based on mobile magnetic gradient tensor system

Energy Technology Data Exchange (ETDEWEB)

Gang, Y.I.N., E-mail: gang.gang88@163.com; Yingtang, Zhang; Zhining, Li; Hongbo, Fan; Guoquan, Ren

2016-03-15

Attitude change of mobile magnetic gradient tensor system critically affects the precision of gradient measurements, thereby increasing ambiguity in target detection. This paper presents a rotational invariant-based method for locating and identifying ferromagnetic targets. Firstly, unit magnetic moment vector was derived based on the geometrical invariant, such that the intermediate eigenvector of the magnetic gradient tensor is perpendicular to the magnetic moment vector and the source–sensor displacement vector. Secondly, unit source–sensor displacement vector was derived based on the characteristic that the angle between magnetic moment vector and source–sensor displacement is a rotational invariant. By introducing a displacement vector between two measurement points, the magnetic moment vector and the source–sensor displacement vector were theoretically derived. To resolve the problem of measurement noises existing in the realistic detection applications, linear equations were formulated using invariants corresponding to several distinct measurement points and least square solution of magnetic moment vector and source–sensor displacement vector were obtained. Results of simulation and principal verification experiment showed the correctness of the analytical method, along with the practicability of the least square method. - Highlights: • Ferromagnetic target detection method is proposed based on rotational invariants • Intermediate eigenvector is perpendicular to magnetic moment and displacement vector • Angle between magnetic moment and displacement vector is a rotational invariant • Magnetic moment and displacement vector are derived based on invariants of two points.

MR-based field-of-view extension in MR/PET: B0 homogenization using gradient enhancement (HUGE).

Science.gov (United States)

Blumhagen, Jan O; Ladebeck, Ralf; Fenchel, Matthias; Scheffler, Klaus

2013-10-01

In whole-body MR/PET, the human attenuation correction can be based on the MR data. However, an MR-based field-of-view (FoV) is limited due to physical restrictions such as B0 inhomogeneities and gradient nonlinearities. Therefore, for large patients, the MR image and the attenuation map might be truncated and the attenuation correction might be biased. The aim of this work is to explore extending the MR FoV through B0 homogenization using gradient enhancement in which an optimal readout gradient field is determined to locally compensate B0 inhomogeneities and gradient nonlinearities. A spin-echo-based sequence was developed that computes an optimal gradient for certain regions of interest, for example, the patient's arms. A significant distortion reduction was achieved outside the normal MR-based FoV. This FoV extension was achieved without any hardware modifications. In-plane distortions in a transaxially extended FoV of up to 600 mm were analyzed in phantom studies. In vivo measurements of the patient's arms lying outside the normal specified FoV were compared with and without the use of B0 homogenization using gradient enhancement. In summary, we designed a sequence that provides data for reducing the image distortions due to B0 inhomogeneities and gradient nonlinearities and used the data to extend the MR FoV. Copyright © 2011 Wiley Periodicals, Inc.

Directory Enabled Policy Based Networking; TOPICAL

International Nuclear Information System (INIS)

KELIIAA, CURTIS M.

2001-01-01

This report presents a discussion of directory-enabled policy-based networking with an emphasis on its role as the foundation for securely scalable enterprise networks. A directory service provides the object-oriented logical environment for interactive cyber-policy implementation. Cyber-policy implementation includes security, network management, operational process and quality of service policies. The leading network-technology vendors have invested in these technologies for secure universal connectivity that transverses Internet, extranet and intranet boundaries. Industry standards are established that provide the fundamental guidelines for directory deployment scalable to global networks. The integration of policy-based networking with directory-service technologies provides for intelligent management of the enterprise network environment as an end-to-end system of related clients, services and resources. This architecture allows logical policies to protect data, manage security and provision critical network services permitting a proactive defense-in-depth cyber-security posture. Enterprise networking imposes the consideration of supporting multiple computing platforms, sites and business-operation models. An industry-standards based approach combined with principled systems engineering in the deployment of these technologies allows these issues to be successfully addressed. This discussion is focused on a directory-based policy architecture for the heterogeneous enterprise network-computing environment and does not propose specific vendor solutions. This document is written to present practical design methodology and provide an understanding of the risks, complexities and most important, the benefits of directory-enabled policy-based networking

MATLAB Simulation of Gradient-Based Neural Network for Online Matrix Inversion

Science.gov (United States)

Zhang, Yunong; Chen, Ke; Ma, Weimu; Li, Xiao-Dong

This paper investigates the simulation of a gradient-based recurrent neural network for online solution of the matrix-inverse problem. Several important techniques are employed as follows to simulate such a neural system. 1) Kronecker product of matrices is introduced to transform a matrix-differential-equation (MDE) to a vector-differential-equation (VDE); i.e., finally, a standard ordinary-differential-equation (ODE) is obtained. 2) MATLAB routine "ode45" is introduced to solve the transformed initial-value ODE problem. 3) In addition to various implementation errors, different kinds of activation functions are simulated to show the characteristics of such a neural network. Simulation results substantiate the theoretical analysis and efficacy of the gradient-based neural network for online constant matrix inversion.

Integrating policy-based management and SLA performance monitoring

Science.gov (United States)

Liu, Tzong-Jye; Lin, Chin-Yi; Chang, Shu-Hsin; Yen, Meng-Tzu

2001-10-01

Policy-based management system provides the configuration capability for the system administrators to focus on the requirements of customers. The service level agreement performance monitoring mechanism helps system administrators to verify the correctness of policies. However, it is difficult for a device to process the policies directly because the policies are the management concept. This paper proposes a mechanism to decompose a policy into rules that can be efficiently processed by a device. Thus, the device may process the rule and collect the performance statistics information efficiently; and the policy-based management system may collect these performance statistics information and report the service-level agreement performance monitoring information to the system administrator. The proposed policy-based management system achieves both the policy configuration and service-level agreement performance monitoring requirements. A policy consists of a condition part and an action part. The condition part is a Boolean expression of a source host IP group, a destination host IP group, etc. The action part is the parameters of services. We say that an address group is compact if it only consists of a range of IP address that can be denoted by a pair of IP address and corresponding IP mask. If the condition part of a policy only consists of the compact address group, we say that the policy is a rule. Since a device can efficiently process a compact address and a system administrator prefers to define a range of IP address, the policy-based management system has to translate policy into rules and supplements the gaps between policy and rules. The proposed policy-based management system builds the relationships between VPN and policies, policy and rules. Since the system administrator wants to monitor the system performance information of VPNs and policies, the proposed policy-based management system downloads the relationships among VPNs, policies and rules to the

Genetically based differentiation in growth of multiple non-native plant species along a steep environmental gradient.

Science.gov (United States)

Haider, Sylvia; Kueffer, Christoph; Edwards, Peter J; Alexander, Jake M

2012-09-01

A non-native plant species spreading along an environmental gradient may need to adjust its growth to the prevailing conditions that it encounters by a combination of phenotypic plasticity and genetic adaptation. There have been several studies of how non-native species respond to changing environmental conditions along latitudinal gradients, but much less is known about elevational gradients. We conducted a climate chamber experiment to investigate plastic and genetically based growth responses of 13 herbaceous non-native plants along an elevational gradient from 100 to 2,000 m a.s.l. in Tenerife. Conditions in the field ranged from high anthropogenic disturbance but generally favourable temperatures for plant growth in the lower half of the gradient, to low disturbance but much cooler conditions in the upper half. We collected seed from low, mid and high elevations and grew them in climate chambers under the characteristic temperatures at these three elevations. Growth of all species was reduced under lower temperatures along both halves of the gradient. We found consistent genetically based differences in growth over the upper elevational gradient, with plants from high-elevation sites growing more slowly than those from mid-elevation ones, while the pattern in the lower part of the gradient was more mixed. Our data suggest that many non-native plants might respond to climate along elevational gradients by genetically based changes in key traits, especially at higher elevations where low temperatures probably impose a stronger selection pressure. At lower elevations, where anthropogenic influences are greater, higher gene flow and frequent disturbance might favour genotypes with broad ecological amplitudes. Thus the importance of evolutionary processes for invasion success is likely to be context-dependent.

Characterization of the Diamond-like Carbon Based Functionally Gradient Film

Institute of Scientific and Technical Information of China (English)

无

2002-01-01

Diamond-like carbon coatings have been used as solid lubricating coatings in vacuum technology for their goodphysical and chemical properties. In this paper, the hybrid technique of unbalanced magnetron sputtering and plasmaimmersion ion implantation (PIll) was adopted to fabricate diamond-like carbon-based functionally gradient film,N/TiN/Ti(N,C)/DLC, on the 304 stainless steel substrate. The film was characterized by using Raman spectroscopyand glancing X-ray diffraction (GXRD), and the topography and surface roughness of the film was observed usingAFM. The mechanical properties of the film were evaluated by nano-indentation. The results showed that the surfaceroughness of the film was approximately 0.732 nm. The hardness and elastic modulus, fracture toughness andinterfacial fracture toughness of N/TiN/Ti(N,C)/DLC functionally gradient film were about 19.84 GPa, 190.03 GPa,3.75 MPa.m1/2 and 5.68 MPa@m1/2, respectively. Compared with that of DLC monolayer and C/TiC/DLC multilayer,this DLC gradient film has better qualities as a solid lubricating coating.

Multimodal image registration based on binary gradient angle descriptor.

Science.gov (United States)

Jiang, Dongsheng; Shi, Yonghong; Yao, Demin; Fan, Yifeng; Wang, Manning; Song, Zhijian

2017-12-01

Multimodal image registration plays an important role in image-guided interventions/therapy and atlas building, and it is still a challenging task due to the complex intensity variations in different modalities. The paper addresses the problem and proposes a simple, compact, fast and generally applicable modality-independent binary gradient angle descriptor (BGA) based on the rationale of gradient orientation alignment. The BGA can be easily calculated at each voxel by coding the quadrant in which a local gradient vector falls, and it has an extremely low computational complexity, requiring only three convolutions, two multiplication operations and two comparison operations. Meanwhile, the binarized encoding of the gradient orientation makes the BGA more resistant to image degradations compared with conventional gradient orientation methods. The BGA can extract similar feature descriptors for different modalities and enable the use of simple similarity measures, which makes it applicable within a wide range of optimization frameworks. The results for pairwise multimodal and monomodal registrations between various images (T1, T2, PD, T1c, Flair) consistently show that the BGA significantly outperforms localized mutual information. The experimental results also confirm that the BGA can be a reliable alternative to the sum of absolute difference in monomodal image registration. The BGA can also achieve an accuracy of [Formula: see text], similar to that of the SSC, for the deformable registration of inhale and exhale CT scans. Specifically, for the highly challenging deformable registration of preoperative MRI and 3D intraoperative ultrasound images, the BGA achieves a similar registration accuracy of [Formula: see text] compared with state-of-the-art approaches, with a computation time of 18.3 s per case. The BGA improves the registration performance in terms of both accuracy and time efficiency. With further acceleration, the framework has the potential for

Gradient-based methods for production optimization of oil reservoirs

Energy Technology Data Exchange (ETDEWEB)

Suwartadi, Eka

2012-07-01

Production optimization for water flooding in the secondary phase of oil recovery is the main topic in this thesis. The emphasis has been on numerical optimization algorithms, tested on case examples using simple hypothetical oil reservoirs. Gradientbased optimization, which utilizes adjoint-based gradient computation, is used to solve the optimization problems. The first contribution of this thesis is to address output constraint problems. These kinds of constraints are natural in production optimization. Limiting total water production and water cut at producer wells are examples of such constraints. To maintain the feasibility of an optimization solution, a Lagrangian barrier method is proposed to handle the output constraints. This method incorporates the output constraints into the objective function, thus avoiding additional computations for the constraints gradient (Jacobian) which may be detrimental to the efficiency of the adjoint method. The second contribution is the study of the use of second-order adjoint-gradient information for production optimization. In order to speedup convergence rate in the optimization, one usually uses quasi-Newton approaches such as BFGS and SR1 methods. These methods compute an approximation of the inverse of the Hessian matrix given the first-order gradient from the adjoint method. The methods may not give significant speedup if the Hessian is ill-conditioned. We have developed and implemented the Hessian matrix computation using the adjoint method. Due to high computational cost of the Newton method itself, we instead compute the Hessian-timesvector product which is used in a conjugate gradient algorithm. Finally, the last contribution of this thesis is on surrogate optimization for water flooding in the presence of the output constraints. Two kinds of model order reduction techniques are applied to build surrogate models. These are proper orthogonal decomposition (POD) and the discrete empirical interpolation method (DEIM

A systematic approach to robust preconditioning for gradient-based inverse scattering algorithms

International Nuclear Information System (INIS)

Nordebo, Sven; Fhager, Andreas; Persson, Mikael; Gustafsson, Mats

2008-01-01

This paper presents a systematic approach to robust preconditioning for gradient-based nonlinear inverse scattering algorithms. In particular, one- and two-dimensional inverse problems are considered where the permittivity and conductivity profiles are unknown and the input data consist of the scattered field over a certain bandwidth. A time-domain least-squares formulation is employed and the inversion algorithm is based on a conjugate gradient or quasi-Newton algorithm together with an FDTD-electromagnetic solver. A Fisher information analysis is used to estimate the Hessian of the error functional. A robust preconditioner is then obtained by incorporating a parameter scaling such that the scaled Fisher information has a unit diagonal. By improving the conditioning of the Hessian, the convergence rate of the conjugate gradient or quasi-Newton methods are improved. The preconditioner is robust in the sense that the scaling, i.e. the diagonal Fisher information, is virtually invariant to the numerical resolution and the discretization model that is employed. Numerical examples of image reconstruction are included to illustrate the efficiency of the proposed technique

Momentum-weighted conjugate gradient descent algorithm for gradient coil optimization.

Science.gov (United States)

Lu, Hanbing; Jesmanowicz, Andrzej; Li, Shi-Jiang; Hyde, James S

2004-01-01

MRI gradient coil design is a type of nonlinear constrained optimization. A practical problem in transverse gradient coil design using the conjugate gradient descent (CGD) method is that wire elements move at different rates along orthogonal directions (r, phi, z), and tend to cross, breaking the constraints. A momentum-weighted conjugate gradient descent (MW-CGD) method is presented to overcome this problem. This method takes advantage of the efficiency of the CGD method combined with momentum weighting, which is also an intrinsic property of the Levenberg-Marquardt algorithm, to adjust step sizes along the three orthogonal directions. A water-cooled, 12.8 cm inner diameter, three axis torque-balanced gradient coil for rat imaging was developed based on this method, with an efficiency of 2.13, 2.08, and 4.12 mT.m(-1).A(-1) along X, Y, and Z, respectively. Experimental data demonstrate that this method can improve efficiency by 40% and field uniformity by 27%. This method has also been applied to the design of a gradient coil for the human brain, employing remote current return paths. The benefits of this design include improved gradient field uniformity and efficiency, with a shorter length than gradient coil designs using coaxial return paths. Copyright 2003 Wiley-Liss, Inc.

Design and Performance of Property Gradient Ternary Nitride Coating Based on Process Control.

Science.gov (United States)

Yan, Pei; Chen, Kaijie; Wang, Yubin; Zhou, Han; Peng, Zeyu; Jiao, Li; Wang, Xibin

2018-05-09

Surface coating is an effective approach to improve cutting tool performance, and multiple or gradient coating structures have become a common development strategy. However, composition mutations at the interfaces decrease the performance of multi-layered coatings. The key mitigation technique has been to reduce the interface effect at the boundaries. This study proposes a structure design method for property-component gradient coatings based on process control. The method produces coatings with high internal cohesion and high external hardness, which could reduce the composition and performance mutations at the interface. A ZrTiN property gradient ternary nitride coating was deposited on cemented carbide by multi-arc ion plating with separated Ti and Zr targets. The mechanical properties, friction behaviors, and cutting performances were systematically investigated, compared with a single-layer coating. The results indicated that the gradient coating had better friction and wear performance with lower wear rate and higher resistance to peeling off during sliding friction. The gradient coating had better wear and damage resistance in cutting processes, with lower machined surface roughness Ra. Gradient-structured coatings could effectively inhibit micro crack initiation and growth under alternating force and temperature load. This method could be extended to similar ternary nitride coatings.

Implementing evidence-based policy in a network setting: road safety policy in the Netherlands.

Science.gov (United States)

Bax, Charlotte; de Jong, Martin; Koppenjan, Joop

2010-01-01

In the early 1990s, in order to improve road safety in The Netherlands, the Institute for Road Safety Research (SWOV) developed an evidence-based "Sustainable Safety" concept. Based on this concept, Dutch road safety policy, was seen as successful and as a best practice in Europe. In The Netherlands, the policy context has now changed from a sectoral policy setting towards a fragmented network in which safety is a facet of other transport-related policies. In this contribution, it is argued that the implementation strategy underlying Sustainable Safety should be aligned with the changed context. In order to explore the adjustments needed, two perspectives of policy implementation are discussed: (1) national evidence-based policies with sectoral implementation; and (2) decentralized negotiation on transport policy in which road safety is but one aspect. We argue that the latter approach matches the characteristics of the newly evolved policy context best, and conclude with recommendations for reformulating the implementation strategy.

A Scalable Policy and SNMP Based Network Management Framework

Institute of Scientific and Technical Information of China (English)

LIU Su-ping; DING Yong-sheng

2009-01-01

Traditional SNMP-based network management can not deal with the task of managing large-scaled distributed network,while policy-based management is one of the effective solutions in network and distributed systems management. However,cross-vendor hardware compatibility is one of the limitations in policy-based management. Devices existing in current network mostly support SNMP rather than Common Open Policy Service (COPS) protocol. By analyzing traditional network management and policy-based network management, a scalable network management framework is proposed. It is combined with Internet Engineering Task Force (IETF) framework for policybased management and SNMP-based network management. By interpreting and translating policy decision to SNMP message,policy can be executed in traditional SNMP-based device.

Combining Step Gradients and Linear Gradients in Density.

Science.gov (United States)

Kumar, Ashok A; Walz, Jenna A; Gonidec, Mathieu; Mace, Charles R; Whitesides, George M

2015-06-16

Combining aqueous multiphase systems (AMPS) and magnetic levitation (MagLev) provides a method to produce hybrid gradients in apparent density. AMPS—solutions of different polymers, salts, or surfactants that spontaneously separate into immiscible but predominantly aqueous phases—offer thermodynamically stable steps in density that can be tuned by the concentration of solutes. MagLev—the levitation of diamagnetic objects in a paramagnetic fluid within a magnetic field gradient—can be arranged to provide a near-linear gradient in effective density where the height of a levitating object above the surface of the magnet corresponds to its density; the strength of the gradient in effective density can be tuned by the choice of paramagnetic salt and its concentrations and by the strength and gradient in the magnetic field. Including paramagnetic salts (e.g., MnSO4 or MnCl2) in AMPS, and placing them in a magnetic field gradient, enables their use as media for MagLev. The potential to create large steps in density with AMPS allows separations of objects across a range of densities. The gradients produced by MagLev provide resolution over a continuous range of densities. By combining these approaches, mixtures of objects with large differences in density can be separated and analyzed simultaneously. Using MagLev to add an effective gradient in density also enables tuning the range of densities captured at an interface of an AMPS by simply changing the position of the container in the magnetic field. Further, by creating AMPS in which phases have different concentrations of paramagnetic ions, the phases can provide different resolutions in density. These results suggest that combining steps in density with gradients in density can enable new classes of separations based on density.

STOCHASTIC GRADIENT METHODS FOR UNCONSTRAINED OPTIMIZATION

Directory of Open Access Journals (Sweden)

Nataša Krejić

2014-12-01

Full Text Available This papers presents an overview of gradient based methods for minimization of noisy functions. It is assumed that the objective functions is either given with error terms of stochastic nature or given as the mathematical expectation. Such problems arise in the context of simulation based optimization. The focus of this presentation is on the gradient based Stochastic Approximation and Sample Average Approximation methods. The concept of stochastic gradient approximation of the true gradient can be successfully extended to deterministic problems. Methods of this kind are presented for the data fitting and machine learning problems.

Stochastic quasi-gradient based optimization algorithms for dynamic reliability applications

International Nuclear Information System (INIS)

Bourgeois, F.; Labeau, P.E.

2001-01-01

On one hand, PSA results are increasingly used in decision making, system management and optimization of system design. On the other hand, when severe accidental transients are considered, dynamic reliability appears appropriate to account for the complex interaction between the transitions between hardware configurations, the operator behavior and the dynamic evolution of the system. This paper presents an exploratory work in which the estimation of the system unreliability in a dynamic context is coupled with an optimization algorithm to determine the 'best' safety policy. Because some reliability parameters are likely to be distributed, the cost function to be minimized turns out to be a random variable. Stochastic programming techniques are therefore envisioned to determine an optimal strategy. Monte Carlo simulation is used at all stages of the computations, from the estimation of the system unreliability to that of the stochastic quasi-gradient. The optimization algorithm is illustrated on a HNO 3 supply system

Block-Based Gradient Descent for Local Backlight Dimming and Flicker Reduction

DEFF Research Database (Denmark)

Burini, Nino; Mantel, Claire; Nadernejad, Ehsan

2014-01-01

Local backlight dimming technology is a two-fold improvement for LED backlit LCD screens that allows to reduce power consumption and increase visual quality. This paper presents a fast version of an iterative backlight dimming algorithm based on gradient descent search. The speed is increased...

Magnetoelectric Transverse Gradient Sensor with High Detection Sensitivity and Low Gradient Noise

OpenAIRE

Zhang, Mingji; Or, Siu Wing

2017-01-01

We report, theoretically and experimentally, the realization of a high detection performance in a novel magnetoelectric (ME) transverse gradient sensor based on the large ME effect and the magnetic field gradient (MFG) technique in a pair of magnetically-biased, electrically-shielded, and mechanically-enclosed ME composites having a transverse orientation and an axial separation. The output voltage of the gradient sensor is directly obtained from the transverse MFG-induced difference in ME vo...

Asynchronous Gossip-Based Gradient-Free Method for Multiagent Optimization

OpenAIRE

Deming Yuan

2014-01-01

This paper considers the constrained multiagent optimization problem. The objective function of the problem is a sum of convex functions, each of which is known by a specific agent only. For solving this problem, we propose an asynchronous distributed method that is based on gradient-free oracles and gossip algorithm. In contrast to the existing work, we do not require that agents be capable of computing the subgradients of their objective functions and coordinating their...

Enhancing Evidence-Based Public Health Policy: Developing and Using Policy Narratives.

Science.gov (United States)

Troy, Lisa M; Kietzman, Kathryn G

2016-06-01

Academic researchers and clinicians have a critical role in shaping public policies to improve the health of an aging America. Policy narratives that pair personal stories with research statistics are a powerful tool to share knowledge generated in academic and clinical settings with policymakers. Effective policy narratives rely on a trustworthy and competent narrator and a compelling story that highlights the personal impact of policies under consideration and academic research that bolsters the story. Awareness of the cultural differences in the motivations, expectations, and institutional constraints of academic researchers and clinicians as information producers and U.S. Congress and federal agencies as information users is critical to the development of policy narratives that impact policy decisions. The current article describes the development and use of policy narratives to bridge cultures and enhance evidence-based public health policies that better meet the needs of older adults. [Journal of Gerontological Nursing, 42(6), 11-17.]. Copyright 2016, SLACK Incorporated.

Constructing regional advantage: platform policies based on related variety and differentiated knowledge bases.

NARCIS (Netherlands)

Asheim, B.T.; Boschma, R.A.; Cooke, P.

2011-01-01

Constructing regional advantage: platform policies based on related variety and differentiated knowledge bases, Regional Studies. This paper presents a regional innovation policy model based on the idea of constructing regional advantage. This policy model brings together concepts like related

Social gradients in child and adolescent antisocial behavior: a systematic review protocol

Directory of Open Access Journals (Sweden)

Piotrowska Patrycja J

2012-08-01

Full Text Available Abstract Background The relationship between social position and physical health is well-established across a range of studies. The evidence base regarding social position and mental health is less well developed, particularly regarding the development of antisocial behavior. Some evidence demonstrates a social gradient in behavioral problems, with children from low-socioeconomic backgrounds experiencing more behavioral difficulties than children from high-socioeconomic families. Antisocial behavior is a heterogeneous concept that encompasses behaviors as diverse as physical fighting, vandalism, stealing, status violation and disobedience to adults. Whether all forms of antisocial behavior show identical social gradients is unclear from previous published research. The mechanisms underlying social gradients in antisocial behavior, such as neighborhood characteristics and family processes, have not been fully elucidated. This review will synthesize findings on the social gradient in antisocial behavior, considering variation across the range of antisocial behaviors and evidence regarding the mechanisms that might underlie the identified gradients. Methods In this review, an extensive manual and electronic literature search will be conducted for papers published from 1960 to 2011. The review will include empirical and quantitative studies of children and adolescents ( Discussion This systematic review has been proposed in order to synthesize cross-disciplinary evidence of the social gradient in antisocial behavior and mechanisms underlying this effect. The results of the review will inform social policies aiming to reduce social inequalities and levels of antisocial behavior, and identify gaps in the present literature to guide further research.

A study of gradient strengthening based on a finite-deformation gradient crystal-plasticity model

Science.gov (United States)

Pouriayevali, Habib; Xu, Bai-Xiang

2017-11-01

A comprehensive study on a finite-deformation gradient crystal-plasticity model which has been derived based on Gurtin's framework (Int J Plast 24:702-725, 2008) is carried out here. This systematic investigation on the different roles of governing components of the model represents the strength of this framework in the prediction of a wide range of hardening behaviors as well as rate-dependent and scale-variation responses in a single crystal. The model is represented in the reference configuration for the purpose of numerical implementation and then implemented in the FEM software ABAQUS via a user-defined subroutine (UEL). Furthermore, a function of accumulation rates of dislocations is employed and viewed as a measure of formation of short-range interactions. Our simulation results reveal that the dissipative gradient strengthening can be identified as a source of isotropic-hardening behavior, which may represent the effect of irrecoverable work introduced by Gurtin and Ohno (J Mech Phys Solids 59:320-343, 2011). Here, the variation of size dependency at different magnitude of a rate-sensitivity parameter is also discussed. Moreover, an observation of effect of a distinctive feature in the model which explains the effect of distortion of crystal lattice in the reference configuration is reported in this study for the first time. In addition, plastic flows in predefined slip systems and expansion of accumulation of GNDs are distinctly observed in varying scales and under different loading conditions.

Ternary gradient metal-organic frameworks.

Science.gov (United States)

Liu, Chong; Rosi, Nathaniel L

2017-09-08

Gradient MOFs contain directional gradients of either structure or functionality. We have successfully prepared two ternary gradient MOFs based on bMOF-100 analogues, namely bMOF-100/102/106 and bMOF-110/100/102, via cascade ligand exchange reactions. The cubic unit cell parameter discrepancy within an individual ternary gradient MOF crystal is as large as ∼1 nm, demonstrating the impressive compatibility and flexibility of the component MOF materials. Because of the presence of a continuum of unit cells, the pore diameters within individual crystals also change in a gradient fashion from ∼2.5 nm to ∼3.0 nm for bMOF-100/102/106, and from ∼2.2 nm to ∼2.7 nm for bMOF-110/100/102, indicating significant porosity gradients. Like previously reported binary gradient MOFs, the composition of the ternary gradient MOFs can be easily controlled by adjusting the reaction conditions. Finally, X-ray diffraction and microspectrophotometry were used to analyse fractured gradient MOF crystals by comparing unit cell parameters and absorbance spectra at different locations, thus revealing the profile of heterogeneity (i.e. gradient distribution of properties) and further confirming the formation of ternary gradient MOFs.

Electrohydromechanical analysis based on conductivity gradient in microchannel

International Nuclear Information System (INIS)

Jiang Hongyuan; Ren Yukun; Ao Hongrui; Ramos, Antonio

2008-01-01

Fluid manipulation is very important in any lab-on-a-chip system. This paper analyses phenomena which use the alternating current (AC) electric field to deflect and manipulate coflowing streams of two different electrolytes (with conductivity gradient) within a microfluidic channel. The basic theory of the electrohydrodynamics and simulation of the analytical model are used to explain the phenomena. The velocity induced for different voltages and conductivity gradient are computed. The results show that when the AC electrical signal is applied on the electrodes, the fluid with higher conductivity occupies a larger region of the channel and the interface of the two fluids is deflected. It will provide some basic reference for people who want to do more study in the control of different fluids with conductivity gradient in a microfluidic channel. (classical areas of phenomenology)

Conjugate gradient based projection - A new explicit methodology for frictional contact

Science.gov (United States)

Tamma, Kumar K.; Li, Maocheng; Sha, Desong

1993-01-01

With special attention towards the applicability to parallel computation or vectorization, a new and effective explicit approach for linear complementary formulations involving a conjugate gradient based projection methodology is proposed in this study for contact problems with Coulomb friction. The overall objectives are focussed towards providing an explicit methodology of computation for the complete contact problem with friction. In this regard, the primary idea for solving the linear complementary formulations stems from an established search direction which is projected to a feasible region determined by the non-negative constraint condition; this direction is then applied to the Fletcher-Reeves conjugate gradient method resulting in a powerful explicit methodology which possesses high accuracy, excellent convergence characteristics, fast computational speed and is relatively simple to implement for contact problems involving Coulomb friction.

A Gradient-Based Multistart Algorithm for Multimodal Aerodynamic Shape Optimization Problems Based on Free-Form Deformation

Science.gov (United States)

Streuber, Gregg Mitchell

Environmental and economic factors motivate the pursuit of more fuel-efficient aircraft designs. Aerodynamic shape optimization is a powerful tool in this effort, but is hampered by the presence of multimodality in many design spaces. Gradient-based multistart optimization uses a sampling algorithm and multiple parallel optimizations to reliably apply fast gradient-based optimization to moderately multimodal problems. Ensuring that the sampled geometries remain physically realizable requires manually developing specialized linear constraints for each class of problem. Utilizing free-form deformation geometry control allows these linear constraints to be written in a geometry-independent fashion, greatly easing the process of applying the algorithm to new problems. This algorithm was used to assess the presence of multimodality when optimizing a wing in subsonic and transonic flows, under inviscid and viscous conditions, and a blended wing-body under transonic, viscous conditions. Multimodality was present in every wing case, while the blended wing-body was found to be generally unimodal.

Testing the limits of gradient sensing.

Directory of Open Access Journals (Sweden)

Vinal Lakhani

2017-02-01

Full Text Available The ability to detect a chemical gradient is fundamental to many cellular processes. In multicellular organisms gradient sensing plays an important role in many physiological processes such as wound healing and development. Unicellular organisms use gradient sensing to move (chemotaxis or grow (chemotropism towards a favorable environment. Some cells are capable of detecting extremely shallow gradients, even in the presence of significant molecular-level noise. For example, yeast have been reported to detect pheromone gradients as shallow as 0.1 nM/μm. Noise reduction mechanisms, such as time-averaging and the internalization of pheromone molecules, have been proposed to explain how yeast cells filter fluctuations and detect shallow gradients. Here, we use a Particle-Based Reaction-Diffusion model of ligand-receptor dynamics to test the effectiveness of these mechanisms and to determine the limits of gradient sensing. In particular, we develop novel simulation methods for establishing chemical gradients that not only allow us to study gradient sensing under steady-state conditions, but also take into account transient effects as the gradient forms. Based on reported measurements of reaction rates, our results indicate neither time-averaging nor receptor endocytosis significantly improves the cell's accuracy in detecting gradients over time scales associated with the initiation of polarized growth. Additionally, our results demonstrate the physical barrier of the cell membrane sharpens chemical gradients across the cell. While our studies are motivated by the mating response of yeast, we believe our results and simulation methods will find applications in many different contexts.

Pixel-based OPC optimization based on conjugate gradients.

Science.gov (United States)

Ma, Xu; Arce, Gonzalo R

2011-01-31

Optical proximity correction (OPC) methods are resolution enhancement techniques (RET) used extensively in the semiconductor industry to improve the resolution and pattern fidelity of optical lithography. In pixel-based OPC (PBOPC), the mask is divided into small pixels, each of which is modified during the optimization process. Two critical issues in PBOPC are the required computational complexity of the optimization process, and the manufacturability of the optimized mask. Most current OPC optimization methods apply the steepest descent (SD) algorithm to improve image fidelity augmented by regularization penalties to reduce the complexity of the mask. Although simple to implement, the SD algorithm converges slowly. The existing regularization penalties, however, fall short in meeting the mask rule check (MRC) requirements often used in semiconductor manufacturing. This paper focuses on developing OPC optimization algorithms based on the conjugate gradient (CG) method which exhibits much faster convergence than the SD algorithm. The imaging formation process is represented by the Fourier series expansion model which approximates the partially coherent system as a sum of coherent systems. In order to obtain more desirable manufacturability properties of the mask pattern, a MRC penalty is proposed to enlarge the linear size of the sub-resolution assistant features (SRAFs), as well as the distances between the SRAFs and the main body of the mask. Finally, a projection method is developed to further reduce the complexity of the optimized mask pattern.

Vandenberg Air Force Base Pressure Gradient Wind Study

Science.gov (United States)

Shafer, Jaclyn A.

2013-01-01

Warning category winds can adversely impact day-to-day space lift operations at Vandenberg Air Force Base (VAFB) in California. NASA's Launch Services Program and other programs at VAFB use wind forecasts issued by the 30 Operational Support Squadron Weather Flight (30 OSSWF) to determine if they need to limit activities or protect property such as a launch vehicle. The 30 OSSWF tasked the AMU to develop an automated Excel graphical user interface that includes pressure gradient thresholds between specific observing stations under different synoptic regimes to aid forecasters when issuing wind warnings. This required the AMU to determine if relationships between the variables existed.

Policy-Based Management Natural Language Parser

Science.gov (United States)

James, Mark

2009-01-01

The Policy-Based Management Natural Language Parser (PBEM) is a rules-based approach to enterprise management that can be used to automate certain management tasks. This parser simplifies the management of a given endeavor by establishing policies to deal with situations that are likely to occur. Policies are operating rules that can be referred to as a means of maintaining order, security, consistency, or other ways of successfully furthering a goal or mission. PBEM provides a way of managing configuration of network elements, applications, and processes via a set of high-level rules or business policies rather than managing individual elements, thus switching the control to a higher level. This software allows unique management rules (or commands) to be specified and applied to a cross-section of the Global Information Grid (GIG). This software embodies a parser that is capable of recognizing and understanding conversational English. Because all possible dialect variants cannot be anticipated, a unique capability was developed that parses passed on conversation intent rather than the exact way the words are used. This software can increase productivity by enabling a user to converse with the system in conversational English to define network policies. PBEM can be used in both manned and unmanned science-gathering programs. Because policy statements can be domain-independent, this software can be applied equally to a wide variety of applications.

Iris Location Algorithm Based on the CANNY Operator and Gradient Hough Transform

Science.gov (United States)

Zhong, L. H.; Meng, K.; Wang, Y.; Dai, Z. Q.; Li, S.

2017-12-01

In the iris recognition system, the accuracy of the localization of the inner and outer edges of the iris directly affects the performance of the recognition system, so iris localization has important research meaning. Our iris data contain eyelid, eyelashes, light spot and other noise, even the gray transformation of the images is not obvious, so the general methods of iris location are unable to realize the iris location. The method of the iris location based on Canny operator and gradient Hough transform is proposed. Firstly, the images are pre-processed; then, calculating the gradient information of images, the inner and outer edges of iris are coarse positioned using Canny operator; finally, according to the gradient Hough transform to realize precise localization of the inner and outer edge of iris. The experimental results show that our algorithm can achieve the localization of the inner and outer edges of the iris well, and the algorithm has strong anti-interference ability, can greatly reduce the location time and has higher accuracy and stability.

Stability of boundary layer flow based on energy gradient theory

Science.gov (United States)

Dou, Hua-Shu; Xu, Wenqian; Khoo, Boo Cheong

2018-05-01

The flow of the laminar boundary layer on a flat plate is studied with the simulation of Navier-Stokes equations. The mechanisms of flow instability at external edge of the boundary layer and near the wall are analyzed using the energy gradient theory. The simulation results show that there is an overshoot on the velocity profile at the external edge of the boundary layer. At this overshoot, the energy gradient function is very large which results in instability according to the energy gradient theory. It is found that the transverse gradient of the total mechanical energy is responsible for the instability at the external edge of the boundary layer, which induces the entrainment of external flow into the boundary layer. Within the boundary layer, there is a maximum of the energy gradient function near the wall, which leads to intensive flow instability near the wall and contributes to the generation of turbulence.

Approximate error conjugation gradient minimization methods

Science.gov (United States)

Kallman, Jeffrey S

2013-05-21

In one embodiment, a method includes selecting a subset of rays from a set of all rays to use in an error calculation for a constrained conjugate gradient minimization problem, calculating an approximate error using the subset of rays, and calculating a minimum in a conjugate gradient direction based on the approximate error. In another embodiment, a system includes a processor for executing logic, logic for selecting a subset of rays from a set of all rays to use in an error calculation for a constrained conjugate gradient minimization problem, logic for calculating an approximate error using the subset of rays, and logic for calculating a minimum in a conjugate gradient direction based on the approximate error. In other embodiments, computer program products, methods, and systems are described capable of using approximate error in constrained conjugate gradient minimization problems.

Far-Infrared Based Pedestrian Detection for Driver-Assistance Systems Based on Candidate Filters, Gradient-Based Feature and Multi-Frame Approval Matching.

Science.gov (United States)

Wang, Guohua; Liu, Qiong

2015-12-21

Far-infrared pedestrian detection approaches for advanced driver-assistance systems based on high-dimensional features fail to simultaneously achieve robust and real-time detection. We propose a robust and real-time pedestrian detection system characterized by novel candidate filters, novel pedestrian features and multi-frame approval matching in a coarse-to-fine fashion. Firstly, we design two filters based on the pedestrians' head and the road to select the candidates after applying a pedestrian segmentation algorithm to reduce false alarms. Secondly, we propose a novel feature encapsulating both the relationship of oriented gradient distribution and the code of oriented gradient to deal with the enormous variance in pedestrians' size and appearance. Thirdly, we introduce a multi-frame approval matching approach utilizing the spatiotemporal continuity of pedestrians to increase the detection rate. Large-scale experiments indicate that the system works in real time and the accuracy has improved about 9% compared with approaches based on high-dimensional features only.

Far-Infrared Based Pedestrian Detection for Driver-Assistance Systems Based on Candidate Filters, Gradient-Based Feature and Multi-Frame Approval Matching

Directory of Open Access Journals (Sweden)

Guohua Wang

2015-12-01

Full Text Available Far-infrared pedestrian detection approaches for advanced driver-assistance systems based on high-dimensional features fail to simultaneously achieve robust and real-time detection. We propose a robust and real-time pedestrian detection system characterized by novel candidate filters, novel pedestrian features and multi-frame approval matching in a coarse-to-fine fashion. Firstly, we design two filters based on the pedestrians’ head and the road to select the candidates after applying a pedestrian segmentation algorithm to reduce false alarms. Secondly, we propose a novel feature encapsulating both the relationship of oriented gradient distribution and the code of oriented gradient to deal with the enormous variance in pedestrians’ size and appearance. Thirdly, we introduce a multi-frame approval matching approach utilizing the spatiotemporal continuity of pedestrians to increase the detection rate. Large-scale experiments indicate that the system works in real time and the accuracy has improved about 9% compared with approaches based on high-dimensional features only.

Time-domain full waveform inversion using the gradient preconditioning based on seismic wave energy: Application to the South China Sea

KAUST Repository

Mengxuan, Zhong

2017-06-01

The gradient preconditioning algorithms based on Hessian matrices in time-domain full waveform inversion (FWI) are widely used now, but consume a lot of memory and do not fit the FWI of large models or actual seismic data well. To avoid the huge storage consumption, the gradient preconditioning approach based on seismic wave energy has been proposed it simulates the “approximated wave field” with the acoustic wave equation and uses the energy of the simulated wavefield to precondition the gradient. The method does not require computing and storing the Hessian matrix or its inverse and can effectively eliminate the effect caused by geometric diffusion and uneven illumination on gradient. The result of experiments in this article with field data from South China Sea confirms that the time-domain FWI using the gradient preconditioning based on seismic wave energy (GPWE) can achieve higher inversion accuracy for the deep high-velocity model and its underlying strata.

$L_{0}$ Gradient Projection.

Science.gov (United States)

Ono, Shunsuke

2017-04-01

Minimizing L 0 gradient, the number of the non-zero gradients of an image, together with a quadratic data-fidelity to an input image has been recognized as a powerful edge-preserving filtering method. However, the L 0 gradient minimization has an inherent difficulty: a user-given parameter controlling the degree of flatness does not have a physical meaning since the parameter just balances the relative importance of the L 0 gradient term to the quadratic data-fidelity term. As a result, the setting of the parameter is a troublesome work in the L 0 gradient minimization. To circumvent the difficulty, we propose a new edge-preserving filtering method with a novel use of the L 0 gradient. Our method is formulated as the minimization of the quadratic data-fidelity subject to the hard constraint that the L 0 gradient is less than a user-given parameter α . This strategy is much more intuitive than the L 0 gradient minimization because the parameter α has a clear meaning: the L 0 gradient value of the output image itself, so that one can directly impose a desired degree of flatness by α . We also provide an efficient algorithm based on the so-called alternating direction method of multipliers for computing an approximate solution of the nonconvex problem, where we decompose it into two subproblems and derive closed-form solutions to them. The advantages of our method are demonstrated through extensive experiments.

An inverse problem strategy based on forward model evaluations: Gradient-based optimization without adjoint solves

Energy Technology Data Exchange (ETDEWEB)

Aguilo Valentin, Miguel Alejandro [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2016-07-01

This study presents a new nonlinear programming formulation for the solution of inverse problems. First, a general inverse problem formulation based on the compliance error functional is presented. The proposed error functional enables the computation of the Lagrange multipliers, and thus the first order derivative information, at the expense of just one model evaluation. Therefore, the calculation of the Lagrange multipliers does not require the solution of the computationally intensive adjoint problem. This leads to significant speedups for large-scale, gradient-based inverse problems.

Phase gradient algorithm based on co-axis two-step phase-shifting interferometry and its application

Science.gov (United States)

Wang, Yawei; Zhu, Qiong; Xu, Yuanyuan; Xin, Zhiduo; Liu, Jingye

2017-12-01

A phase gradient method based on co-axis two-step phase-shifting interferometry, is used to reveal the detailed information of a specimen. In this method, the phase gradient distribution can only be obtained by calculating both the first-order derivative and the radial Hilbert transformation of the intensity difference between two phase-shifted interferograms. The feasibility and accuracy of this method were fully verified by the simulation results for a polystyrene sphere and a red blood cell. The empirical results demonstrated that phase gradient is sensitive to changes in the refractive index and morphology. Because phase retrieval and tedious phase unwrapping are not required, the calculation speed is faster. In addition, co-axis interferometry has high spatial resolution.

Magnetoelectric Transverse Gradient Sensor with High Detection Sensitivity and Low Gradient Noise.

Science.gov (United States)

Zhang, Mingji; Or, Siu Wing

2017-10-25

We report, theoretically and experimentally, the realization of a high detection performance in a novel magnetoelectric (ME) transverse gradient sensor based on the large ME effect and the magnetic field gradient (MFG) technique in a pair of magnetically-biased, electrically-shielded, and mechanically-enclosed ME composites having a transverse orientation and an axial separation. The output voltage of the gradient sensor is directly obtained from the transverse MFG-induced difference in ME voltage between the two ME composites and is calibrated against transverse MFGs to give a high detection sensitivity of 0.4-30.6 V/(T/m), a strong common-mode magnetic field noise rejection rate of gradient noise of 0.16-620 nT/m/ Hz in a broad frequency range of 1 Hz-170 kHz under a small baseline of 35 mm. An analysis of experimental gradient noise spectra obtained in a magnetically-unshielded laboratory environment reveals the domination of the pink (1/ f ) noise, dielectric loss noise, and power-frequency noise below 3 kHz, in addition to the circuit noise above 3 kHz, in the gradient sensor. The high detection performance, together with the added merit of passive and direct ME conversion by the large ME effect in the ME composites, makes the gradient sensor suitable for the passive, direct, and broadband detection of transverse MFGs.

Pressure gradients fail to predict diffusio-osmosis

Science.gov (United States)

Liu, Yawei; Ganti, Raman; Frenkel, Daan

2018-05-01

We present numerical simulations of diffusio-osmotic flow, i.e. the fluid flow generated by a concentration gradient along a solid-fluid interface. In our study, we compare a number of distinct approaches that have been proposed for computing such flows and compare them with a reference calculation based on direct, non-equilibrium molecular dynamics simulations. As alternatives, we consider schemes that compute diffusio-osmotic flow from the gradient of the chemical potentials of the constituent species and from the gradient of the component of the pressure tensor parallel to the interface. We find that the approach based on treating chemical potential gradients as external forces acting on various species agrees with the direct simulations, thereby supporting the approach of Marbach et al (2017 J. Chem. Phys. 146 194701). In contrast, an approach based on computing the gradients of the microscopic pressure tensor does not reproduce the direct non-equilibrium results.

Persistent misunderstandings about evidence-based (sorry: informed!) policy-making.

Science.gov (United States)

Bédard, Pierre-Olivier; Ouimet, Mathieu

2016-01-01

The field of research on knowledge mobilization and evidence-informed policy-making has seen enduring debates related to various fundamental assumptions such as the definition of 'evidence', the relative validity of various research methods, the actual role of evidence to inform policy-making, etc. In many cases, these discussions serve a useful purpose, but they also stem from serious disagreement on methodological and epistemological issues. This essay reviews the rationale for evidence-informed policy-making by examining some of the common claims made about the aims and practices of this perspective on public policy. Supplementing the existing justifications for evidence-based policy making, we argue in favor of a greater inclusion of research evidence in the policy process but in a structured fashion, based on methodological considerations. In this respect, we present an overview of the intricate relation between policy questions and appropriate research designs. By closely examining the relation between research questions and research designs, we claim that the usual points of disagreement are mitigated. For instance, when focusing on the variety of research designs that can answer a range of policy questions, the common critical claim about 'RCT-based policy-making' seems to lose some, if not all of its grip.

Gradient Evolution-based Support Vector Machine Algorithm for Classification

Science.gov (United States)

Zulvia, Ferani E.; Kuo, R. J.

2018-03-01

This paper proposes a classification algorithm based on a support vector machine (SVM) and gradient evolution (GE) algorithms. SVM algorithm has been widely used in classification. However, its result is significantly influenced by the parameters. Therefore, this paper aims to propose an improvement of SVM algorithm which can find the best SVMs’ parameters automatically. The proposed algorithm employs a GE algorithm to automatically determine the SVMs’ parameters. The GE algorithm takes a role as a global optimizer in finding the best parameter which will be used by SVM algorithm. The proposed GE-SVM algorithm is verified using some benchmark datasets and compared with other metaheuristic-based SVM algorithms. The experimental results show that the proposed GE-SVM algorithm obtains better results than other algorithms tested in this paper.

Environment based innovation: policy questions

Directory of Open Access Journals (Sweden)

Mario Rui Silva

2009-12-01

Full Text Available Natural resources and physical cultural resources, referred to in this paper as “Environmental Resources”, can be important assets for regional competitiveness and innovation. In recent years, these types of assets have been increasingly taken into consideration in the design and implementation of regional development strategies, as a consequence of their potential role as a source of differentiation and of new competitive advantages. However, in contrast to environmental policies, which usually focus on the protection of the environment, innovation policies and their instruments are largely shaped by, and geared towards, knowledge-based innovation.In this paper, we discuss the role played by environmental resources in the context of regional innovation policies. We begin by discussing the relationship between environmental resources and regional development, and by emphasizing some contrasting views with regard to the function of environmental resources in regional development. Then, we address the relationship between regional competitive advantages and innovation strategies. The specific issues and problems that arise whenever the aim is to attain competitive advantages through the valorisation of environmental resources constitute the core of section III. In that section, we highlight the specific characteristics of environmental resources and we discuss the applicability of the “natural resource curse” argument to the dynamics based on the valorisation of environmental resources. The reasons that justify public interventionas well as the difficulties concerning the adequate level of intervention (local / regional / national are also examined. The paper ends with some conclusions and policy implications.

Energy harvesting from vibration of Timoshenko nanobeam under base excitation considering flexoelectric and elastic strain gradient effects

Science.gov (United States)

Managheb, S. A. M.; Ziaei-Rad, S.; Tikani, R.

2018-05-01

The coupling between polarization and strain gradients is called flexoelectricity. This phenomenon exists in all dielectrics with any symmetry. In this paper, energy harvesting from a Timoshenko beam is studied by considering the flexoelectric and strain gradient effects. General governing equations and related boundary conditions are derived using Hamilton's principle. The flexoelectric effects are defined by gradients of normal and shear strains which lead to a more general model. The developed model also covers the classical Timoshenko beam theory by ignoring the flexoelectric effect. Based on the developed model, flexoelectricity effect on dielectric beams and energy harvesting from cantilever beam under harmonic base excitation is investigated. A parametric study was conducted to evaluate the effects of flexoelectric coefficients, strain gradient constants, base acceleration and the attaching tip mass on the energy harvested from a cantilever Timoshenko beam. Results show that the flexoelectricity has a significant effect on the energy harvester performance, especially in submicron and nano scales. In addition, this effect makes the beam to behave softer than before and also it changes the harvester first resonance frequency. The present study provides guidance for flexoelectric nano-beam analysis and a method to evaluate the performance of energy harvester in nano-dielectric devices.

Dose gradient analyses in linac-based intracranial stereotactic radiosurgery using paddick's gradient index. Consideration of the optimal method for plan evaluation

International Nuclear Information System (INIS)

Ohtakara, Kazuhiro; Hayashi, Shinya; Hoshi, Hiroaki

2011-01-01

The objective of our study was to describe the dose gradient characteristics of Linac-based stereotactic radiosurgery using Paddick's gradient index (GI) and to elucidate the factors influencing the GI value. Seventy-three plans for brain metastases using the dynamic conformal arcs were reviewed. The GI values were calculated at the 80% and 90% isodose surfaces (IDSs) and at the different target coverage IDSs (D99, D95, D90, and D85). The GI values significantly decreased as the target coverage of the reference IDS increased (the percentage of the IDS decreased). There was a significant inverse correlation between the GI values and target volume. The plans generated with the addition of a 1-mm leaf margin had worse GI values both at the D99 and D95 relative to those without leaf margin. The number and arrangement of arcs also affected the GI value. The GI values are highly sensitive to the IDS selection variability for dose prescription or evaluation, the target volume, and the planning method. To objectively compare the quality of dose gradient between rival plans, it would be preferable to employ the GI defined at the reference IDS indicating the specific target coverage (exempli gratia (e.g.), D95), irrespective of the intended marginal dose. The modified GI (mGI), defined in this study, substituting the denominator of the original GI with the target volume, would be useful to compensate for the false superior GI value in cases of target over-coverage with the reference IDS and to objectively evaluate the dose gradient outside the target boundary. (author)

A study of microindentation hardness tests by mechanism-based strain gradient plasticity

International Nuclear Information System (INIS)

Huang, Y.; Xue, Z.; Gao, H.; Nix, W. D.; Xia, Z. C.

2000-01-01

We recently proposed a theory of mechanism-based strain gradient (MSG) plasticity to account for the size dependence of plastic deformation at micron- and submicron-length scales. The MSG plasticity theory connects micron-scale plasticity to dislocation theories via a multiscale, hierarchical framework linking Taylor's dislocation hardening model to strain gradient plasticity. Here we show that the theory of MSG plasticity, when used to study micro-indentation, indeed reproduces the linear dependence observed in experiments, thus providing an important self-consistent check of the theory. The effects of pileup, sink-in, and the radius of indenter tip have been taken into account in the indentation model. In accomplishing this objective, we have generalized the MSG plasticity theory to include the elastic deformation in the hierarchical framework. (c) 2000 Materials Research Society

An assessment of long term ecosystem research activities across European socio-ecological gradients.

Science.gov (United States)

Metzger, M J; Bunce, R G H; van Eupen, M; Mirtl, M

2010-06-01

Integration of European long term ecosystem research (LTER) would provide important support for the management of the pan-European environment and ecosystems, as well as international policy commitments. This does require appropriate coverage of Europe and standardised frameworks and research methods between countries. Emerging interest in socio-ecological systems prompted the present assessment of the distribution of LTER activities across European socio-ecological gradients. This paper presents a European stratification with a 1 km(2) resolution, delineating 48 broad socio-ecological regions. The dataset is based on an existing biogeophysical stratification constructed using multivariate clustering of mainly climatic variables and a newly developed socio-economic stratification based on an economic density indicator. The coverage of European LTER facilities across the socio-ecological gradients is tested using this dataset. The analysis shows two strong biases in the present LTER effort. Firstly, urban and disturbed regions are consistently under-represented, illustrating a bias for traditional ecological research away from human activity. Secondly, the Mediterranean, for which some of the most extreme global change impacts are projected, is receiving comparatively little attention. Both findings can help guide future investment in the European LTER network - and especially in a Long Term Socio-Ecological Research (LTSER) component- to provide a more balanced coverage. This will provide better scientific understanding of pan-European environmental concerns and support the management of natural resources and international policy commitments in the European Union. (c) 2010 Elsevier Ltd. All rights reserved.

Gradient-type methods in inverse parabolic problems

International Nuclear Information System (INIS)

Kabanikhin, Sergey; Penenko, Aleksey

2008-01-01

This article is devoted to gradient-based methods for inverse parabolic problems. In the first part, we present a priori convergence theorems based on the conditional stability estimates for linear inverse problems. These theorems are applied to backwards parabolic problem and sideways parabolic problem. The convergence conditions obtained coincide with sourcewise representability in the self-adjoint backwards parabolic case but they differ in the sideways case. In the second part, a variational approach is formulated for a coefficient identification problem. Using adjoint equations, a formal gradient of an objective functional is constructed. A numerical test illustrates the performance of conjugate gradient algorithm with the formal gradient.

The Urban-Rural Gradient In Asthma: A Population-Based Study in Northern Europe

Directory of Open Access Journals (Sweden)

Signe Timm

2015-12-01

Full Text Available The early life environment appears to have a persistent impact on asthma risk. We hypothesize that environmental factors related to rural life mediate lower asthma prevalence in rural populations, and aimed to investigate an urban-rural gradient, assessed by place of upbringing, for asthma. The population-based Respiratory Health In Northern Europe (RHINE study includes subjects from Denmark, Norway, Sweden, Iceland and Estonia born 1945–1973. The present analysis encompasses questionnaire data on 11,123 RHINE subjects. Six categories of place of upbringing were defined: farm with livestock, farm without livestock, village in rural area, small town, city suburb and inner city. The association of place of upbringing with asthma onset was analysed with Cox regression adjusted for relevant confounders. Subjects growing up on livestock farms had less asthma (8% than subjects growing up in inner cities (11% (hazard ratio 0.72 95% CI 0.57–0.91, and a significant urban-rural gradient was observed across six urbanisation levels (p = 0.02. An urban-rural gradient was only evident among women, smokers and for late-onset asthma. Analyses on wheeze and place of upbringing revealed similar results. In conclusion, this study suggests a protective effect of livestock farm upbringing on asthma development and an urban-rural gradient in a Northern European population.

An algorithm for gradient-based dynamic optimization of UV flash processes

DEFF Research Database (Denmark)

Ritschel, Tobias Kasper Skovborg; Capolei, Andrea; Gaspar, Jozsef

2017-01-01

This paper presents a novel single-shooting algorithm for gradient-based solution of optimal control problems with vapor-liquid equilibrium constraints. Such optimal control problems are important in several engineering applications, for instance in control of distillation columns, in certain two...... softwareaswellastheperformanceofdifferentcompilersinaLinuxoperatingsystem. Thesetestsindicatethatreal-timenonlinear model predictive control of UV flash processes is computationally feasible....

Strengthening Research Capacity and Evidence-Based Policy ...

International Development Research Centre (IDRC) Digital Library (Canada)

... wider Central Asian region lack capacity to conduct empirical analysis and create policies based on research evidence. To address government priorities, the region needs quality research driven by local demands and analytical skills that can inform effective development responses through policy. This 39-month project, ...

Role of ideas and ideologies in evidence-based health policy.

Science.gov (United States)

Prinja, S

2010-01-01

Policy making in health is largely thought to be driven by three 'I's namely ideas, interests and institutions. Recent years have seen a shift in approach with increasing reliance being placed on role of evidence for policy making. The present article ascertains the role of ideas and ideologies in shaping evidence which is used to aid in policy decisions. The article discusses different theories of research-policy interface and the relative freedom of research-based evidence from the influence of ideas. Examples from developed and developed countries are cited to illustrate the contentions made. The article highlights the complexity of the process of evidence-based policy making, in a world driven by existing political, social and cultural ideologies. Consideration of this knowledge is paramount where more efforts are being made to bridge the gap between the 'two worlds' of researchers and policy makers to make evidence-based policy as also for policy analysts.

Quaternion Gradient and Hessian

OpenAIRE

Xu, Dongpo; Mandic, Danilo P.

2014-01-01

The optimization of real scalar functions of quaternion variables, such as the mean square error or array output power, underpins many practical applications. Solutions typically require the calculation of the gradient and Hessian. However, real functions of quaternion variables are essentially nonanalytic, which are prohibitive to the development of quaternion-valued learning systems. To address this issue, we propose new definitions of quaternion gradient and Hessian, based on the novel gen...

Segmentation of DTI based on tensorial morphological gradient

Science.gov (United States)

Rittner, Leticia; de Alencar Lotufo, Roberto

2009-02-01

This paper presents a segmentation technique for diffusion tensor imaging (DTI). This technique is based on a tensorial morphological gradient (TMG), defined as the maximum dissimilarity over the neighborhood. Once this gradient is computed, the tensorial segmentation problem becomes an scalar one, which can be solved by conventional techniques, such as watershed transform and thresholding. Similarity functions, namely the dot product, the tensorial dot product, the J-divergence and the Frobenius norm, were compared, in order to understand their differences regarding the measurement of tensor dissimilarities. The study showed that the dot product and the tensorial dot product turned out to be inappropriate for computation of the TMG, while the Frobenius norm and the J-divergence were both capable of measuring tensor dissimilarities, despite the distortion of Frobenius norm, since it is not an affine invariant measure. In order to validate the TMG as a solution for DTI segmentation, its computation was performed using distinct similarity measures and structuring elements. TMG results were also compared to fractional anisotropy. Finally, synthetic and real DTI were used in the method validation. Experiments showed that the TMG enables the segmentation of DTI by watershed transform or by a simple choice of a threshold. The strength of the proposed segmentation method is its simplicity and robustness, consequences of TMG computation. It enables the use, not only of well-known algorithms and tools from the mathematical morphology, but also of any other segmentation method to segment DTI, since TMG computation transforms tensorial images in scalar ones.

Topographic gradient based site characterization in India complemented by strong ground-motion spectral attributes

KAUST Repository

Nath, Sankar Kumar; Thingbaijam, Kiran Kumar; Adhikari, M. D.; Nayak, Avinash; Devaraj, N.; Ghosh, Soumalya K.; Mahajan, Arun K.

2013-01-01

We appraise topographic-gradient approach for site classification that employs correlations between 30. m column averaged shear-wave velocity and topographic gradients. Assessments based on site classifications reported from cities across India indicate that the approach is reasonably viable at regional level. Additionally, we experiment three techniques for site classification based on strong ground-motion recordings, namely Horizontal-to-Vertical Spectral Ratio (HVSR), Response Spectra Shape (RSS), and Horizontal-to-Vertical Response Spectral Ratio (HVRSR) at the strong motion stations located across the Himalayas and northeast India. Statistical tests on the results indicate that these three techniques broadly differentiate soil and rock sites while RSS and HVRSR yield better signatures. The results also support the implemented site classification in the light of strong ground-motion spectral attributes observed in different parts of the globe. © 2013 Elsevier Ltd.

Topographic gradient based site characterization in India complemented by strong ground-motion spectral attributes

KAUST Repository

Nath, Sankar Kumar

2013-12-01

We appraise topographic-gradient approach for site classification that employs correlations between 30. m column averaged shear-wave velocity and topographic gradients. Assessments based on site classifications reported from cities across India indicate that the approach is reasonably viable at regional level. Additionally, we experiment three techniques for site classification based on strong ground-motion recordings, namely Horizontal-to-Vertical Spectral Ratio (HVSR), Response Spectra Shape (RSS), and Horizontal-to-Vertical Response Spectral Ratio (HVRSR) at the strong motion stations located across the Himalayas and northeast India. Statistical tests on the results indicate that these three techniques broadly differentiate soil and rock sites while RSS and HVRSR yield better signatures. The results also support the implemented site classification in the light of strong ground-motion spectral attributes observed in different parts of the globe. © 2013 Elsevier Ltd.

Identification and prognostic value of anterior gradient protein 2 expression in breast cancer based on tissue microarray.

Science.gov (United States)

Guo, Jilong; Gong, Guohua; Zhang, Bin

2017-07-01

Breast cancer has attracted substantial attention as one of the major cancers causing death in women. It is crucial to find potential biomarkers of prognostic value in breast cancer. In this study, the expression pattern of anterior gradient protein 2 in breast cancer was identified based on the main molecular subgroups. Through analysis of 69 samples from the Gene Expression Omnibus database, we found that anterior gradient protein 2 expression was significantly higher in non-triple-negative breast cancer tissues compared with normal tissues and triple-negative breast cancer tissues (p gradient protein 2 expression pattern. Furthermore, we performed immunohistochemical analysis. The quantification results revealed that anterior gradient protein 2 is highly expressed in non-triple-negative breast cancer (grade 3 excluded) and grade 1 + 2 (triple-negative breast cancer excluded) tumours compared with normal tissues. Anterior gradient protein 2 was significantly highly expressed in non-triple-negative breast cancer (grade 3 excluded) and non-triple-negative breast cancer tissues compared with triple-negative breast cancer tissues (p gradient protein 2 was significantly highly expressed in grade 1 + 2 (triple-negative breast cancer excluded) and grade 1 + 2 tissues compared with grade 3 tissues (p gradient protein 2 expression was significantly associated with histologic type, histological grade, oestrogen status and progesterone status. Univariate analysis of clinicopathological variables showed that anterior gradient protein 2 expression, tumour size and lymph node status were significantly correlated with overall survival in patients with grade 1 and 2 tumours. Cox multivariate analysis revealed anterior gradient protein 2 as a putative independent indicator of unfavourable outcomes (p = 0.031). All these data clearly showed that anterior gradient protein 2 is highly expressed in breast cancer and can be regarded as a putative biomarker for

Router Agent Technology for Policy-Based Network Management

Science.gov (United States)

Chow, Edward T.; Sudhir, Gurusham; Chang, Hsin-Ping; James, Mark; Liu, Yih-Chiao J.; Chiang, Winston

2011-01-01

This innovation can be run as a standalone network application on any computer in a networked environment. This design can be configured to control one or more routers (one instance per router), and can also be configured to listen to a policy server over the network to receive new policies based on the policy- based network management technology. The Router Agent Technology transforms the received policies into suitable Access Control List syntax for the routers it is configured to control. It commits the newly generated access control lists to the routers and provides feedback regarding any errors that were faced. The innovation also automatically generates a time-stamped log file regarding all updates to the router it is configured to control. This technology, once installed on a local network computer and started, is autonomous because it has the capability to keep listening to new policies from the policy server, transforming those policies to router-compliant access lists, and committing those access lists to a specified interface on the specified router on the network with any error feedback regarding commitment process. The stand-alone application is named RouterAgent and is currently realized as a fully functional (version 1) implementation for the Windows operating system and for CISCO routers.

Time dependent policy-based access control

DEFF Research Database (Denmark)

Vasilikos, Panagiotis; Nielson, Flemming; Nielson, Hanne Riis

2017-01-01

also on other attributes of the environment such as the time. In this paper, we use systems of Timed Automata to model distributed systems and we present a logic in which one can express time-dependent policies for access control. We show how a fragment of our logic can be reduced to a logic......Access control policies are essential to determine who is allowed to access data in a system without compromising the data's security. However, applications inside a distributed environment may require those policies to be dependent on the actual content of the data, the flow of information, while...... that current model checkers for Timed Automata such as UPPAAL can handle and we present a translator that performs this reduction. We then use our translator and UPPAAL to enforce time-dependent policy-based access control on an example application from the aerospace industry....

ADAPTIVE ANT COLONY OPTIMIZATION BASED GRADIENT FOR EDGE DETECTION

Directory of Open Access Journals (Sweden)

Febri Liantoni

2014-08-01

Full Text Available Ant Colony Optimization (ACO is a nature-inspired optimization algorithm which is motivated by ants foraging behavior. Due to its favorable advantages, ACO has been widely used to solve several NP-hard problems, including edge detection. Since ACO initially distributes ants at random, it may cause imbalance ant distribution which later affects path discovery process. In this paper an adaptive ACO is proposed to optimize edge detection by adaptively distributing ant according to gradient analysis. Ants are adaptively distributed according to gradient ratio of each image regions. Region which has bigger gradient ratio, will have bigger number of ant distribution. Experiments are conducted using images from various datasets. Precision and recall are used to quantitatively evaluate performance of the proposed algorithm. Precision and recall of adaptive ACO reaches 76.98 % and 96.8 %. Whereas highest precision and recall for standard ACO are 69.74 % and 74.85 %. Experimental results show that the adaptive ACO outperforms standard ACO which randomly distributes ants.

Policy administration in tag-based authorization

NARCIS (Netherlands)

Etalle, Sandro; Hinrichs, Timothy L.; Lee, Adam J.; Trivellato, Daniel; Zannone, Nicola

2013-01-01

Tag-Based Authorization (TBA) is a hybrid access control model that combines the ease of use of extensional access control models with the expressivity of logic-based formalisms. The main limitation of TBA is that it lacks support for policy administration. More precisely, it does not allow

Combining rate-based and cap-and-trade emissions policies

International Nuclear Information System (INIS)

Fischer, Carolyn

2003-12-01

Rate-based emissions policies (like tradable performance standards, TPS) fix average emissions intensity, while cap-and-trade (CAT) policies fix total emissions. This paper shows that unfettered trade between rate-based and cap-and-trade programs always raises combined emissions, except when product markets are related in particular ways. Gains from trade are fully passed on to consumers in the rate-based sector, resulting in more output and greater emissions allocations. We consider several policy options to offset the expansion, including a tax, an 'exchange rate' to adjust for relative permit values, output-based allocation (OBA) for the rate-based sector, and tightening the cap. A range of combinations of tighter allocations could improve situations in both sectors with trade while holding emissions constant

Investigation of Size-Dependency in Free-Vibration of Micro-Resonators Based on the Strain Gradient Theory

Directory of Open Access Journals (Sweden)

R. Vatankhah

Full Text Available Abstract This paper investigates the vibration behavior of micro-resonators based on the strain gradient theory, a non-classical continuum theory capable of capturing the size effect appearing in micro-scale structures. The micro-resonator is modeled as a clamped-clamped micro-beam with an attached mass subjected to an axial force. The governing equations of motion and both classical and non-classical sets of boundary conditions are developed based on the strain gradient theory. The normalized natural frequency of the micro-resonator is evaluated and the influences of various parameters are assessed. In addition, the current results are compared to those of the classical and modified couple stress continuum theories.

A physics-based model for maintenance of the pH gradient in the gastric mucus layer.

Science.gov (United States)

Lewis, Owen L; Keener, James P; Fogelson, Aaron L

2017-12-01

It is generally accepted that the gastric mucus layer provides a protective barrier between the lumen and the mucosa, shielding the mucosa from acid and digestive enzymes and preventing autodigestion of the stomach epithelium. However, the precise mechanisms that contribute to this protective function are still up for debate. In particular, it is not clear what physical processes are responsible for transporting hydrogen protons, secreted within the gastric pits, across the mucus layer to the lumen without acidifying the environment adjacent to the epithelium. One hypothesis is that hydrogen may be bound to the mucin polymers themselves as they are convected away from the mucosal surface and eventually degraded in the stomach lumen. It is also not clear what mechanisms prevent hydrogen from diffusing back toward the mucosal surface, thereby lowering the local pH. In this work we investigate a physics-based model of ion transport within the mucosal layer based on a Nernst-Planck-like equation. Analysis of this model shows that the mechanism of transporting protons bound to the mucus gel is capable of reproducing the trans-mucus pH gradients reported in the literature. Furthermore, when coupled with ion exchange at the epithelial surface, our analysis shows that bicarbonate secretion alone is capable of neutralizing the epithelial pH, even in the face of enormous diffusive gradients of hydrogen. Maintenance of the pH gradient is found to be robust to a wide array of perturbations in both physiological and phenomenological model parameters, suggesting a robust physiological control mechanism. NEW & NOTEWORTHY This work combines modeling techniques based on physical principles, as well as novel numerical simulations to test the plausibility of one hypothesized mechanism for proton transport across the gastric mucus layer. Results show that this mechanism is able to maintain the extreme pH gradient seen in in vivo experiments and suggests a highly robust regulation

Gradient for the acoustic VTI full waveform inversion based on the instantaneous traveltime sensitivity kernels

KAUST Repository

Djebbi, Ramzi

2015-08-19

The instantaneous traveltime is able to reduce the non-linearity of full waveform inversion (FWI) that originates from the wrapping of the phase. However, the adjoint state method in this case requires a total of 5 modeling calculations to compute the gradient. Also, considering the larger modeling cost for anisotropic wavefield extrapolation and the necessity to use a line-search algorithm to estimate a step length that depends on the parameters scale, we propose to calculate the gradient based on the instantaneous traveltime sensitivity kernels. We, specifically, use the sensitivity kernels computed using dynamic ray-tracing to build the gradient. The resulting update is computed using a matrix decomposition and accordingly the computational cost is reduced. We consider a simple example where an anomaly is embedded into a constant background medium and we compute the update for the VTI wave equation parameterized using vh, η and ε.

Gradient for the acoustic VTI full waveform inversion based on the instantaneous traveltime sensitivity kernels

KAUST Repository

Djebbi, Ramzi; Alkhalifah, Tariq Ali

2015-01-01

The instantaneous traveltime is able to reduce the non-linearity of full waveform inversion (FWI) that originates from the wrapping of the phase. However, the adjoint state method in this case requires a total of 5 modeling calculations to compute the gradient. Also, considering the larger modeling cost for anisotropic wavefield extrapolation and the necessity to use a line-search algorithm to estimate a step length that depends on the parameters scale, we propose to calculate the gradient based on the instantaneous traveltime sensitivity kernels. We, specifically, use the sensitivity kernels computed using dynamic ray-tracing to build the gradient. The resulting update is computed using a matrix decomposition and accordingly the computational cost is reduced. We consider a simple example where an anomaly is embedded into a constant background medium and we compute the update for the VTI wave equation parameterized using vh, η and ε.

Ultra-high gradient compact accelerator developments

NARCIS (Netherlands)

Brussaard, G.J.H.; Wiel, van der M.J.

2004-01-01

Continued development of relatively compact, although not quite 'table-top', lasers with peak powers in the range up to 100 TW has enabled laser-plasma-based acceleration experiments with amazing gradients of up to 1 TV/m. In order to usefully apply such gradients to 'controlled' acceleration,

Research on n-γ discrimination method based on spectrum gradient analysis of signals

International Nuclear Information System (INIS)

Luo Xiaoliang; Liu Guofu; Yang Jun; Wang Yueke

2013-01-01

Having discovered that there are distinct differences between the spectrum gradient of the output neutron and γ-ray signal from liquid scintillator detectors, this paper presented a n-γ discrimination method called spectrum gradient analysis (SGA) based on frequency-domain features of the pulse signals. The basic principle and feasibility of SGA method were discussed and the validity of n-γ discrimination results of SGA was verified by the associated particle neutron flight experiment. The discrimination performance of SGA was evaluated under different conditions of sampling rates ranging from 5 G/s to 250 M/s. The results show that SGA method exhibits insensitivity to noise, strong anti-interference ability, stable discrimination performance and lower amount of calculation in contrast with time-domain n-γ discrimination methods. (authors)

Gradient-based stochastic estimation of the density matrix

Science.gov (United States)

Wang, Zhentao; Chern, Gia-Wei; Batista, Cristian D.; Barros, Kipton

2018-03-01

Fast estimation of the single-particle density matrix is key to many applications in quantum chemistry and condensed matter physics. The best numerical methods leverage the fact that the density matrix elements f(H)ij decay rapidly with distance rij between orbitals. This decay is usually exponential. However, for the special case of metals at zero temperature, algebraic decay of the density matrix appears and poses a significant numerical challenge. We introduce a gradient-based probing method to estimate all local density matrix elements at a computational cost that scales linearly with system size. For zero-temperature metals, the stochastic error scales like S-(d+2)/2d, where d is the dimension and S is a prefactor to the computational cost. The convergence becomes exponential if the system is at finite temperature or is insulating.

Segmentasi Pembuluh Darah Retina Pada Citra Fundus Menggunakan Gradient Based Adaptive Thresholding Dan Region Growing

Directory of Open Access Journals (Sweden)

Deni Sutaji

2016-07-01

Full Text Available AbstrakSegmentasi pembuluh darah pada citra fundus retina menjadi hal yang substansial dalam dunia kedokteran, karena dapat digunakan untuk mendeteksi penyakit, seperti: diabetic retinopathy, hypertension, dan cardiovascular. Dokter membutuhkan waktu sekitar dua jam untuk mendeteksi pembuluh darah retina, sehingga diperlukan metode yang dapat membantu screening agar lebih cepat.Penelitian sebelumnya mampu melakukan segmentasi pembuluh darah yang sensitif terhadap variasi ukuran lebar pembuluh darah namun masih terjadi over-segmentasi pada area patologi. Oleh karena itu, penelitian ini bertujuan untuk mengembangkan metode segmentasi pembuluh darah pada citra fundus retina yang dapat mengurangi over-segmentasi pada area patologi menggunakan Gradient Based Adaptive Thresholding dan Region Growing.Metode yang diusulkan terdiri dari 3 tahap, yaitu segmentasi pembuluh darah utama, deteksi area patologi dan segmentasi pembuluh darah tipis. Tahap segmentasi pembuluh darah utama menggunakan high-pass filtering dan tophat reconstruction pada kanal hijau citra yang sudah diperbaiki kontrasnya sehingga lebih jelas perbedaan antara pembuluh darah dan background. Tahap deteksi area patologi menggunakan metode Gradient Based Adaptive Thresholding. Tahap segmentasi pembuluh darah tipis menggunakan Region Growing berdasarkan informasi label pembuluh darah utama dan label area patologi. Hasil segmentasi pembuluh darah utama dan pembuluh darah tipis kemudian digabungkan sehingga menjadi keluaran sistem berupa citra biner pembuluh darah. Berdasarkan hasil uji coba, metode ini mampu melakukan segmentasi pembuluh darah retina dengan baik pada citra fundus DRIVE, yaitu dengan akurasi rata-rata 95.25% dan nilai Area Under Curve (AUC pada kurva Relative Operating Characteristic (ROC sebesar 74.28%.                           Kata Kunci: citra fundus retina, gradient based adaptive thresholding, patologi, pembuluh darah retina, region growing

The Adjoint Method for Gradient-based Dynamic Optimization of UV Flash Processes

DEFF Research Database (Denmark)

Ritschel, Tobias Kasper Skovborg; Capolei, Andrea; Jørgensen, John Bagterp

2017-01-01

This paper presents a novel single-shooting algorithm for gradient-based solution of optimal control problems with vapor-liquid equilibrium constraints. Dynamic optimization of UV flash processes is relevant in nonlinear model predictive control of distillation columns, certain two-phase flow pro......-component flash process which demonstrate the importance of the optimization solver, the compiler, and the linear algebra software for the efficiency of dynamic optimization of UV flash processes....

Worship Discourse and White Race-based Policy Attitudes

Science.gov (United States)

Brown, R. Khari; Kaiser, Angela; Jackson, James S.

2014-01-01

The current study relies upon the 2004 National Politics Study to examine the association between exposure to race-based messages within places of worship and White race-based policy attitudes. The present study challenges the notion that, for White Americans, religiosity inevitably leads to racial prejudice. Rather, we argue, as others have, that religion exists on a continuum that spans from reinforcing to challenging the status quo of social inequality. Our findings suggests that the extent to which Whites discuss race along with the potential need for public policy solutions to address racial inequality within worship spaces, worship attendance contributes to support for public policies aimed at reducing racial inequality. On the other hand, apolitical and non-structural racial discussions within worship settings do seemingly little to move many Whites to challenge dominant idealistic perceptions of race that eschews public policy interventions as solutions to racial inequality. PMID:25324579

Illicit Drugs, Policing and the Evidence-Based Policy Paradigm

Science.gov (United States)

Ritter, Alison; Lancaster, Kari

2013-01-01

The mantra of evidence-based policy (EBP) suggests that endeavours to implement evidence-based policing will produce better outcomes. However there is dissonance between the rhetoric of EBP and the actuality of policing policy. This disjuncture is critically analysed using the case study of illicit drugs policing. The dissonance may be ameliorated…

On the Implications of Knowledge Bases for Regional Innovation Policies in Germany

Directory of Open Access Journals (Sweden)

Hassink Robert

2014-12-01

Full Text Available Regional innovation policies have been criticised for being too standardised, one-size-fits-all and place-neutral in character. Embedded in these debates, this paper has two aims: first, to analyse whether industries with different knowledge bases in regions in Germany have different needs for regional innovation policies, and secondly, to investigate whether knowledge bases can contribute to the fine-tuning of regional innovation policies in particular and to a modern, tailor-made, place-based regional innovation policy in general. It concludes that although needs differ due to differences in knowledge bases, those bases are useful only to a limited extent in fine-tuning regional innovation policies

A blind deconvolution method based on L1/L2 regularization prior in the gradient space

Science.gov (United States)

Cai, Ying; Shi, Yu; Hua, Xia

2018-02-01

In the process of image restoration, the result of image restoration is very different from the real image because of the existence of noise, in order to solve the ill posed problem in image restoration, a blind deconvolution method based on L1/L2 regularization prior to gradient domain is proposed. The method presented in this paper first adds a function to the prior knowledge, which is the ratio of the L1 norm to the L2 norm, and takes the function as the penalty term in the high frequency domain of the image. Then, the function is iteratively updated, and the iterative shrinkage threshold algorithm is applied to solve the high frequency image. In this paper, it is considered that the information in the gradient domain is better for the estimation of blur kernel, so the blur kernel is estimated in the gradient domain. This problem can be quickly implemented in the frequency domain by fast Fast Fourier Transform. In addition, in order to improve the effectiveness of the algorithm, we have added a multi-scale iterative optimization method. This paper proposes the blind deconvolution method based on L1/L2 regularization priors in the gradient space can obtain the unique and stable solution in the process of image restoration, which not only keeps the edges and details of the image, but also ensures the accuracy of the results.

Policy-Based Negotiation Engine for Cross-Domain Interoperability

Science.gov (United States)

Vatan, Farrokh; Chow, Edward T.

2012-01-01

A successful policy negotiation scheme for Policy-Based Management (PBM) has been implemented. Policy negotiation is the process of determining the "best" communication policy that all of the parties involved can agree on. Specifically, the problem is how to reconcile the various (and possibly conflicting) communication protocols used by different divisions. The solution must use protocols available to all parties involved, and should attempt to do so in the best way possible. Which protocols are commonly available, and what the definition of "best" is will be dependent on the parties involved and their individual communications priorities.

Content-addressable memory based enforcement of configurable policies

Science.gov (United States)

Berg, Michael J

2014-05-06

A monitoring device for monitoring transactions on a bus includes content-addressable memory ("CAM") and a response policy unit. The CAM includes an input coupled to receive a bus transaction tag based on bus traffic on the bus. The CAM stores data tags associated with rules of a security policy to compare the bus transaction tag to the data tags. The CAM generates an output signal indicating whether one or more matches occurred. The response policy unit is coupled to the CAM to receive the output signal from the CAM and to execute a policy action in response to the output signal.

Optimization of offshore wind turbine support structures using analytical gradient-based method

OpenAIRE

Chew, Kok Hon; Tai, Kang; Ng, E.Y.K.; Muskulus, Michael

2015-01-01

Design optimization of the offshore wind turbine support structure is an expensive task; due to the highly-constrained, non-convex and non-linear nature of the design problem. This report presents an analytical gradient-based method to solve this problem in an efficient and effective way. The design sensitivities of the objective and constraint functions are evaluated analytically while the optimization of the structure is performed, subject to sizing, eigenfrequency, extreme load an...

The Evolution of Policy Enactment on Gender-Based Violence in Schools

Science.gov (United States)

Parkes, Jenny

2016-01-01

This article examines how policies and strategies to address school-related gender-based violence have evolved since 2000, when gender-based violence within education was largely invisible. Through an exploration of policy enactment in three countries--Liberia, South Africa, and Brazil--it traces remarkable progress in policy, programmes, and…

Hidden policy ciphertext-policy attribute-based encryption with keyword search against keyword guessing attack

Institute of Scientific and Technical Information of China (English)

Shuo; QIU; Jiqiang; LIU; Yanfeng; SHI; Rui; ZHANG

2017-01-01

Attribute-based encryption with keyword search(ABKS) enables data owners to grant their search capabilities to other users by enforcing an access control policy over the outsourced encrypted data. However,existing ABKS schemes cannot guarantee the privacy of the access structures, which may contain some sensitive private information. Furthermore, resulting from the exposure of the access structures, ABKS schemes are susceptible to an off-line keyword guessing attack if the keyword space has a polynomial size. To solve these problems, we propose a novel primitive named hidden policy ciphertext-policy attribute-based encryption with keyword search(HP-CPABKS). With our primitive, the data user is unable to search on encrypted data and learn any information about the access structure if his/her attribute credentials cannot satisfy the access control policy specified by the data owner. We present a rigorous selective security analysis of the proposed HP-CPABKS scheme, which simultaneously keeps the indistinguishability of the keywords and the access structures. Finally,the performance evaluation verifies that our proposed scheme is efficient and practical.

A pH-Sensing Optode for Mapping Spatiotemporal Gradients in 3D Paper-Based Cell Cultures.

Science.gov (United States)

Kenney, Rachael M; Boyce, Matthew W; Whitman, Nathan A; Kromhout, Brenden P; Lockett, Matthew R

2018-02-06

Paper-based cultures are an emerging platform for preparing 3D tissue-like structures. Chemical gradients can be imposed upon these cultures, generating microenvironments similar to those found in poorly vascularized tumors. There is increasing evidence that the tumor microenvironment is responsible for promoting drug resistance and increased invasiveness. Acidosis, or the acidification of the extracellular space, is particularly important in promoting these aggressive cancer phenotypes. To better understand how cells respond to acidosis there is a need for 3D culture platforms that not only model relevant disease states but also contain sensors capable of quantifying small molecules in the extracellular environment. In this work, we describe pH-sensing optodes that are capable of generating high spatial and temporal resolution maps of pH gradients in paper-based cultures. This sensor was fabricated by suspending microparticles containing pH-sensitive (fluorescein) and pH-insensitive (diphenylanthracene) dyes in a polyurethane hydrogel, which was then coated onto a transparent film. The pH-sensing films have a fast response time, are reversible, stable in long-term culture environments, have minimal photobleaching, and are not cytotoxic. These films have a pK a of 7.61 ± 0.04 and are sensitive in the pH range corresponding to normal and tumorigenic tissues. With these optodes, we measured the spatiotemporal evolution of pH gradients in paper-based tumor models.

The influence of ALN-Al gradient material gradient index on ballistic performance

International Nuclear Information System (INIS)

Wang Youcong; Liu Qiwen; Li Yao; Shen Qiang

2013-01-01

Ballistic performance of the gradient material is superior to laminated material, and gradient materials have different gradient types. Using ls-dyna to simulate the ballistic performance of ALN-AL gradient target plates which contain three gradient index (b = 1, b = 0.5, b = 2). Through Hopkinson bar numerical simulation to the target plate materials, we obtained the reflection stress wave and transmission stress wave state of gradient material to get the best gradient index. The internal stress state of gradient material is simulated by amplification processing of the target plate model. When the gradient index b is equal to 1, the gradient target plate is best of all.

Variational Level Set Method for Two-Stage Image Segmentation Based on Morphological Gradients

Directory of Open Access Journals (Sweden)

Zemin Ren

2014-01-01

Full Text Available We use variational level set method and transition region extraction techniques to achieve image segmentation task. The proposed scheme is done by two steps. We first develop a novel algorithm to extract transition region based on the morphological gradient. After this, we integrate the transition region into a variational level set framework and develop a novel geometric active contour model, which include an external energy based on transition region and fractional order edge indicator function. The external energy is used to drive the zero level set toward the desired image features, such as object boundaries. Due to this external energy, the proposed model allows for more flexible initialization. The fractional order edge indicator function is incorporated into the length regularization term to diminish the influence of noise. Moreover, internal energy is added into the proposed model to penalize the deviation of the level set function from a signed distance function. The results evolution of the level set function is the gradient flow that minimizes the overall energy functional. The proposed model has been applied to both synthetic and real images with promising results.

Method and means for a spatial and temporal probe for laser-generated plumes based on density gradients

Science.gov (United States)

Yeung, E.S.; Chen, G.

1990-05-01

A method and means are disclosed for a spatial and temporal probe for laser generated plumes based on density gradients includes generation of a plume of vaporized material from a surface by an energy source. The probe laser beam is positioned so that the plume passes through the probe laser beam. Movement of the probe laser beam caused by refraction from the density gradient of the plume is monitored. Spatial and temporal information, correlated to one another, is then derived. 15 figs.

Comparative analysis of gradient-field-based orientation estimation methods and regularized singular-value decomposition for fringe pattern processing.

Science.gov (United States)

Sun, Qi; Fu, Shujun

2017-09-20

Fringe orientation is an important feature of fringe patterns and has a wide range of applications such as guiding fringe pattern filtering, phase unwrapping, and abstraction. Estimating fringe orientation is a basic task for subsequent processing of fringe patterns. However, various noise, singular and obscure points, and orientation data degeneration lead to inaccurate calculations of fringe orientation. Thus, to deepen the understanding of orientation estimation and to better guide orientation estimation in fringe pattern processing, some advanced gradient-field-based orientation estimation methods are compared and analyzed. At the same time, following the ideas of smoothing regularization and computing of bigger gradient fields, a regularized singular-value decomposition (RSVD) technique is proposed for fringe orientation estimation. To compare the performance of these gradient-field-based methods, quantitative results and visual effect maps of orientation estimation are given on simulated and real fringe patterns that demonstrate that the RSVD produces the best estimation results at a cost of relatively less time.

Evidence-based policy? The use of mobile phones in hospital

NARCIS (Netherlands)

Ettelt, Stefanie; Nolte, Ellen; McKee, Martin; Haugen, Odd Arild; Karlberg, Ingvar; Klazinga, Niek; Ricciardi, Walter; Teperi, Juha

2006-01-01

BACKGROUND: Evidence-based policies have become increasingly accepted in clinical practice. However, policies on many of the non-clinical activities that take place in health care facilities may be less frequently evidence based. METHODS: We carried out a review of literature on safety of mobile

Gradient waveform synthesis for magnetic propulsion using MRI gradient coils

International Nuclear Information System (INIS)

Han, B H; Lee, S Y; Park, S

2008-01-01

Navigating an untethered micro device in a living subject is of great interest for both diagnostic and therapeutic applications. Magnetic propulsion of an untethered device carrying a magnetic core in it is one of the promising methods to navigate the device. MRI gradients coils are thought to be suitable for navigating the device since they are capable of magnetic propulsion in any direction while providing magnetic resonance images. For precise navigation of the device, especially in the peripheral region of the gradient coils, the concomitant gradient fields, as well as the linear gradient fields in the main magnetic field direction, should be considered in driving the gradient coils. For simple gradient coil configurations, the Maxwell coil in the z-direction and the Golay coil in the x- and y-directions, we have calculated the magnetic force fields, which are not necessarily the same as the conventional linear gradient fields of MRI. Using the calculated magnetic force fields, we have synthesized gradient waveforms to navigate the device along a desired path

[Landscape pattern gradient dynamics and desakota features in rapid urbanization area: a case study in Panyu of Guangzhou].

Science.gov (United States)

Yu, Long-Sheng; Fu, Yi-Fu; Yu, Huai-Yi; Li, Zhi-Qin

2011-01-01

In order to understand the landscape pattern gradient dynamics and desakota features in rapid urbanization area, this paper took the rapidly urbanizing Panyu District of Guangzhou City as a case, and analyzed its land use and land cover data, based on four Landsat TM images from 1990 to 2008. With the combination of gradient analysis and landscape pattern analysis, and by using the landscape indices in both class and landscape scales, the spatial dynamics and desakota feature of this rapidly urbanizing district were quantified. In the study district, there was a significant change in the landscape pattern, and a typical desakota feature presented along buffer gradient zones. Urban landscape increased and expanded annually, accompanied with serious fragmentation of agricultural landscape. The indices patch density, contagion, and landscape diversity, etc., changed regularly in the urbanization gradient, and the peak of landscape indices appeared in the gradient zone of 4-6 km away from the urban center. The landscape patterns at time series also reflected the differences among the dynamics in different gradient zones. The landscape pattern in desakota region was characterized by complex patch shape, high landscape diversity and fragmentation, and remarkable landscape dynamics. The peaks of landscape indices spread from the urban center to border areas, and desakota region was expanding gradually. The general trend of spatiotemporal dynamics in desakota region and its driving forces were discussed, which could be benefit to the regional land use policy-making and sustainable development planning.

Game Algorithm for Resource Allocation Based on Intelligent Gradient in HetNet

Directory of Open Access Journals (Sweden)

Fang Ye

2017-02-01

Full Text Available In order to improve system performance such as throughput, heterogeneous network (HetNet has become an effective solution in Long Term Evolution-Advanced (LET-A. However, co-channel interference leads to degradation of the HetNet throughput, because femtocells are always arranged to share the spectrum with the macro base station. In this paper, in view of the serious cross-layer interference in double layer HetNet, the Stackelberg game model is adopted to analyze the resource allocation methods of the network. Unlike the traditional system models only focusing on macro base station performance improvement, we take into account the overall system performance and build a revenue function with convexity. System utility functions are defined as the average throughput, which does not adopt frequency spectrum trading method, so as to avoid excessive signaling overhead. Due to the value scope of continuous Nash equilibrium of the built game model, the gradient iterative algorithm is introduced to reduce the computational complexity. As for the solution of Nash equilibrium, one kind of gradient iterative algorithm is proposed, which is able to intelligently choose adjustment factors. The Nash equilibrium can be quickly solved; meanwhile, the step of presetting adjustment factors is avoided according to network parameters in traditional linear iterative model. Simulation results show that the proposed algorithm enhances the overall performance of the system.

Extrusion-based 3D printing of poly(propylene fumarate) scaffolds with hydroxyapatite gradients

Science.gov (United States)

Trachtenberg, Jordan E.; Placone, Jesse K.; Smith, Brandon T.; Fisher, John P.; Mikos, Antonios G.

2017-01-01

The primary focus of this work is to present the current challenges of printing scaffolds with concentration gradients of nanoparticles with an aim to improve the processing of these scaffolds. Furthermore, we address how print fidelity is related to material composition and emphasize the importance of considering this relationship when developing complex scaffolds for bone implants. The ability to create complex tissues is becoming increasingly relevant in the tissue engineering community. For bone tissue engineering applications, this work demonstrates the ability to use extrusion-based printing techniques to control the spatial deposition of hydroxyapatite (HA) nanoparticles in a 3D composite scaffold. In doing so, we combined the benefits of synthetic, degradable polymers, such as poly(propylene fumarate) (PPF), with osteoconductive HA nanoparticles that provide robust compressive mechanical properties. Furthermore, the final 3D printed scaffolds consisted of well-defined layers with interconnected pores, two critical features for a successful bone implant. To demonstrate a controlled gradient of HA, thermogravimetric analysis was carried out to quantify HA on a per-layer basis. Moreover, we non-destructively evaluated the tendency of HA particles to aggregate within PPF using micro-computed tomography (µCT). This work provides insight for proper fabrication and characterization of composite scaffolds containing particle gradients and has broad applicability for future efforts in fabricating complex scaffolds for tissue engineering applications. PMID:28125380

Flexoelectricity: strain gradient effects in ferroelectrics

Energy Technology Data Exchange (ETDEWEB)

Ma Wenhui [Department of Physics, Shantou Unversity, Shantou, Guangdong 515063 (China)

2007-12-15

Mechanical strain gradient induced polarization effect or flexoelectricity in perovskite-type ferroelectric and relaxor ferroelectric ceramics was investigated. The flexoelectric coefficients measured at room temperature ranged from about 1 {mu} C m{sup -1} for lead zirconate titanate to 100 {mu} C m{sup -1} for barium strontium titanate. Flexoelectric effects were discovered to be sensitive to chemical makeup, phase symmetry, and domain structures. Based on phenomenological discussion and experimental data on flexoelectricity, the present study proposed that mechanical strain gradient field could influence polarization responses in a way analogous to electric field. Flexoelectric coefficients were found to be nonlinearly enhanced by dielectric permittivity and strain gradient. Interfacial mismatch in epitaxial thin films can give rise to high strain gradients, enabling flexoelectric effects to make a significant impact in properly engineered ferroelectric heterostructure systems.

On fracture in finite strain gradient plasticity

DEFF Research Database (Denmark)

Martínez Pañeda, Emilio; Niordson, Christian Frithiof

2016-01-01

In this work a general framework for damage and fracture assessment including the effect of strain gradients is provided. Both mechanism-based and phenomenological strain gradient plasticity (SGP) theories are implemented numerically using finite deformation theory and crack tip fields are invest......In this work a general framework for damage and fracture assessment including the effect of strain gradients is provided. Both mechanism-based and phenomenological strain gradient plasticity (SGP) theories are implemented numerically using finite deformation theory and crack tip fields...... are investigated. Differences and similarities between the two approaches within continuum SGP modeling are highlighted and discussed. Local strain hardening promoted by geometrically necessary dislocations (GNDs) in the vicinity of the crack leads to much higher stresses, relative to classical plasticity...... in the multiple parameter version of the phenomenological SGP theory. Since this also dominates the mechanics of indentation testing, results suggest that length parameters characteristic of mode I fracture should be inferred from nanoindentation....

The Role Played by Agricultural Policy-based Finance in New Village Construction

Institute of Scientific and Technical Information of China (English)

2011-01-01

The necessity of the agricultural policy-based finance in terms of supporting the new village construction is analyzed: in the first place, the theoretical roots of agricultural policy-based finance supporting new village construction are "market failure" and "government intervention"; in the second place, the continual decline of agriculture and the "rural financial market failure" in recent years have become the objective evidence and historical mission for agricultural policy-based finance to support new village construction; in the third place, the combination of agricultural policy-based finance and new village construction is conducive to solving the "three agriculture" problems and facilitating the reform of new village construction. The feasibility of the support is analyzed: firstly, agricultural policy-based finance boasts the status and position of the "primary drive" in new village construction; secondly, the nation continuously deepens the reform of rural financial system and policy-based banks and strengthens the functions of Agricultural Development Bank, which provides policies for agricultural policy-based finance to support new village construction; thirdly, the 14 years’ reform and development of Agricultural Development Bank and the eleventh five year plan lay sound practical basis for the support of agricultural policy-based finance to new village construction. Based on the necessity and feasibility, the following six aspects are analyzed to fully display the function of the "first engine" of agricultural policy-related finance to new village construction. Firstly, strengthening the credit and loan aid to grain and cotton and some other agricultural products in the circulation domain; secondly, strengthening the credit and loan aid to agricultural industrialization in processing field; thirdly, intensifying the credit and loan aid to agricultural comprehensive development, rural infrastructure construction, application and promotion of

Self-induced temperature gradients in Brownian dynamics

Science.gov (United States)

Devine, Jack; Jack, M. W.

2017-12-01

Brownian systems often surmount energy barriers by absorbing and emitting heat to and from their local environment. Usually, the temperature gradients created by this heat exchange are assumed to dissipate instantaneously. Here we relax this assumption to consider the case where Brownian dynamics on a time-independent potential can lead to self-induced temperature gradients. In the same way that externally imposed temperature gradients can cause directed motion, these self-induced gradients affect the dynamics of the Brownian system. The result is a coupling between the local environment and the Brownian subsystem. We explore the resulting dynamics and thermodynamics of these coupled systems and develop a robust method for numerical simulation. In particular, by focusing on one-dimensional situations, we show that self-induced temperature gradients reduce barrier-crossing rates. We also consider a heat engine and a heat pump based on temperature gradients induced by a Brownian system in a nonequilibrium potential.

Accelerated gradient-based free form deformable registration for online adaptive radiotherapy

International Nuclear Information System (INIS)

Yu, Gang; Yang, Guanyu; Shu, Huazhong; Li, Baosheng; Liang, Yueqiang; Yin, Yong; Li, Dengwang

2015-01-01

The registration of planning fan-beam computed tomography (FBCT) and daily cone-beam CT (CBCT) is a crucial step in adaptive radiation therapy. The current intensity-based registration algorithms, such as Demons, may fail when they are used to register FBCT and CBCT, because the CT numbers in CBCT cannot exactly correspond to the electron densities. In this paper, we investigated the effects of CBCT intensity inaccuracy on the registration accuracy and developed an accurate gradient-based free form deformation algorithm (GFFD). GFFD distinguishes itself from other free form deformable registration algorithms by (a) measuring the similarity using the 3D gradient vector fields to avoid the effect of inconsistent intensities between the two modalities; (b) accommodating image sampling anisotropy using the local polynomial approximation-intersection of confidence intervals (LPA-ICI) algorithm to ensure a smooth and continuous displacement field; and (c) introducing a ‘bi-directional’ force along with an adaptive force strength adjustment to accelerate the convergence process. It is expected that such a strategy can decrease the effect of the inconsistent intensities between the two modalities, thus improving the registration accuracy and robustness. Moreover, for clinical application, the algorithm was implemented by graphics processing units (GPU) through OpenCL framework. The registration time of the GFFD algorithm for each set of CT data ranges from 8 to 13 s. The applications of on-line adaptive image-guided radiation therapy, including auto-propagation of contours, aperture-optimization and dose volume histogram (DVH) in the course of radiation therapy were also studied by in-house-developed software. (paper)

Fast gradient-based methods for Bayesian reconstruction of transmission and emission PET images

International Nuclear Information System (INIS)

Mumcuglu, E.U.; Leahy, R.; Zhou, Z.; Cherry, S.R.

1994-01-01

The authors describe conjugate gradient algorithms for reconstruction of transmission and emission PET images. The reconstructions are based on a Bayesian formulation, where the data are modeled as a collection of independent Poisson random variables and the image is modeled using a Markov random field. A conjugate gradient algorithm is used to compute a maximum a posteriori (MAP) estimate of the image by maximizing over the posterior density. To ensure nonnegativity of the solution, a penalty function is used to convert the problem to one of unconstrained optimization. Preconditioners are used to enhance convergence rates. These methods generally achieve effective convergence in 15--25 iterations. Reconstructions are presented of an 18 FDG whole body scan from data collected using a Siemens/CTI ECAT931 whole body system. These results indicate significant improvements in emission image quality using the Bayesian approach, in comparison to filtered backprojection, particularly when reprojections of the MAP transmission image are used in place of the standard attenuation correction factors

3D printing for the design and fabrication of polymer-based gradient scaffolds.

Science.gov (United States)

Bracaglia, Laura G; Smith, Brandon T; Watson, Emma; Arumugasaamy, Navein; Mikos, Antonios G; Fisher, John P

2017-07-01

To accurately mimic the native tissue environment, tissue engineered scaffolds often need to have a highly controlled and varied display of three-dimensional (3D) architecture and geometrical cues. Additive manufacturing in tissue engineering has made possible the development of complex scaffolds that mimic the native tissue architectures. As such, architectural details that were previously unattainable or irreproducible can now be incorporated in an ordered and organized approach, further advancing the structural and chemical cues delivered to cells interacting with the scaffold. This control over the environment has given engineers the ability to unlock cellular machinery that is highly dependent upon the intricate heterogeneous environment of native tissue. Recent research into the incorporation of physical and chemical gradients within scaffolds indicates that integrating these features improves the function of a tissue engineered construct. This review covers recent advances on techniques to incorporate gradients into polymer scaffolds through additive manufacturing and evaluate the success of these techniques. As covered here, to best replicate different tissue types, one must be cognizant of the vastly different types of manufacturing techniques available to create these gradient scaffolds. We review the various types of additive manufacturing techniques that can be leveraged to fabricate scaffolds with heterogeneous properties and discuss methods to successfully characterize them. Additive manufacturing techniques have given tissue engineers the ability to precisely recapitulate the native architecture present within tissue. In addition, these techniques can be leveraged to create scaffolds with both physical and chemical gradients. This work offers insight into several techniques that can be used to generate graded scaffolds, depending on the desired gradient. Furthermore, it outlines methods to determine if the designed gradient was achieved. This review

Application of an online ion-chromatography-based instrument for gradient flux measurements of speciated nitrogen and sulfur

Science.gov (United States)

Rumsey, Ian C.; Walker, John T.

2016-06-01

The dry component of total nitrogen and sulfur atmospheric deposition remains uncertain. The lack of measurements of sufficient chemical speciation and temporal extent make it difficult to develop accurate mass budgets and sufficient process level detail is not available to improve current air-surface exchange models. Over the past decade, significant advances have been made in the development of continuous air sampling measurement techniques, resulting with instruments of sufficient sensitivity and temporal resolution to directly quantify air-surface exchange of nitrogen and sulfur compounds. However, their applicability is generally restricted to only one or a few of the compounds within the deposition budget. Here, the performance of the Monitor for AeRosols and GAses in ambient air (MARGA 2S), a commercially available online ion-chromatography-based analyzer is characterized for the first time as applied for air-surface exchange measurements of HNO3, NH3, NH4+, NO3-, SO2 and SO42-. Analytical accuracy and precision are assessed under field conditions. Chemical concentrations gradient precision are determined at the same sampling site. Flux uncertainty measured by the aerodynamic gradient method is determined for a representative 3-week period in fall 2012 over a grass field. Analytical precision and chemical concentration gradient precision were found to compare favorably in comparison to previous studies. During the 3-week period, percentages of hourly chemical concentration gradients greater than the corresponding chemical concentration gradient detection limit were 86, 42, 82, 73, 74 and 69 % for NH3, NH4+, HNO3, NO3-, SO2 and SO42-, respectively. As expected, percentages were lowest for aerosol species, owing to their relatively low deposition velocities and correspondingly smaller gradients relative to gas phase species. Relative hourly median flux uncertainties were 31, 121, 42, 43, 67 and 56 % for NH3, NH4+, HNO3, NO3-, SO2 and SO42-, respectively. Flux

An optical flow algorithm based on gradient constancy assumption for PIV image processing

International Nuclear Information System (INIS)

Zhong, Qianglong; Yang, Hua; Yin, Zhouping

2017-01-01

Particle image velocimetry (PIV) has matured as a flow measurement technique. It enables the description of the instantaneous velocity field of the flow by analyzing the particle motion obtained from digitally recorded images. Correlation based PIV evaluation technique is widely used because of its good accuracy and robustness. Although very successful, correlation PIV technique has some weakness which can be avoided by optical flow based PIV algorithms. At present, most of the optical flow methods applied to PIV are based on brightness constancy assumption. However, some factors of flow imaging technology and the nature property of the fluids make the brightness constancy assumption less appropriate in real PIV cases. In this paper, an implementation of a 2D optical flow algorithm (GCOF) based on gradient constancy assumption is introduced. The proposed GCOF assumes the edges of the illuminated PIV particles are constant during motion. It comprises two terms: a combined local-global gradient data term and a first-order divergence and vorticity smooth term. The approach can provide accurate dense motion fields. The approach are tested on synthetic images and on two experimental flows. The comparison of GCOF with other optical flow algorithms indicates the proposed method is more accurate especially in conditions of illumination variation. The comparison of GCOF with correlation PIV technique shows that the proposed GCOF has advantages on preserving small divergence and vorticity structures of the motion field and getting less outliers. As a consequence, the GCOF acquire a more accurate and better topological description of the turbulent flow. (paper)

Policy and Validity Prospects for Performance-Based Assessment.

Science.gov (United States)

Baker, Eva L.; And Others

1994-01-01

This article describes performance-based assessment as expounded by its proponents, comments on these conceptions, reviews evidence regarding the technical quality of performance-based assessment, and considers its validity under various policy options. (JDD)

Determination of accelerated factors in gradient descent iterations based on Taylor's series

Directory of Open Access Journals (Sweden)

Petrović Milena

2017-01-01

Full Text Available In this paper the efficiency of accelerated gradient descent methods regarding the way of determination of accelerated factor is considered. Due to the previous researches we assert that the use of Taylor's series of posed gradient descent iteration in calculation of accelerated parameter gives better final results than some other choices. We give a comparative analysis of efficiency of several methods with different approaches in obtaining accelerated parameter. According to the achieved results of numerical experiments we make a conclusion about the one of the most optimal way in defining accelerated parameter in accelerated gradient descent schemes.

Batch Policy Gradient Methods for Improving Neural Conversation Models

OpenAIRE

Kandasamy, Kirthevasan; Bachrach, Yoram; Tomioka, Ryota; Tarlow, Daniel; Carter, David

2017-01-01

We study reinforcement learning of chatbots with recurrent neural network architectures when the rewards are noisy and expensive to obtain. For instance, a chatbot used in automated customer service support can be scored by quality assurance agents, but this process can be expensive, time consuming and noisy. Previous reinforcement learning work for natural language processing uses on-policy updates and/or is designed for on-line learning settings. We demonstrate empirically that such strateg...

Evaluation of extreme ionospheric total electron content gradient associated with plasma bubbles for GNSS Ground-Based Augmentation System

Science.gov (United States)

Saito, S.; Yoshihara, T.

2017-08-01

Associated with plasma bubbles, extreme spatial gradients in ionospheric total electron content (TEC) were observed on 8 April 2008 at Ishigaki (24.3°N, 124.2°E, +19.6° magnetic latitude), Japan. The largest gradient was 3.38 TECU km-1 (total electron content unit, 1 TECU = 1016 el m-2), which is equivalent to an ionospheric delay gradient of 540 mm km-1 at the GPS L1 frequency (1.57542 GHz). This value is confirmed by using multiple estimating methods. The observed value exceeds the maximum ionospheric gradient that has ever been observed (412 mm km-1 or 2.59 TECU km-1) to be associated with a severe magnetic storm. It also exceeds the assumed maximum value (500 mm km-1 or 3.08 TECU km-1) which was used to validate the draft international standard for Global Navigation Satellite System (GNSS) Ground-Based Augmentation Systems (GBAS) to support Category II/III approaches and landings. The steepest part of this extreme gradient had a scale size of 5.3 km, and the front-normal velocities were estimated to be 71 m s-1 with a wavefront-normal direction of east-northeastward. The total width of the transition region from outside to inside the plasma bubble was estimated to be 35.3 km. The gradient of relatively small spatial scale size may fall between an aircraft and a GBAS ground subsystem and may be undetectable by both aircraft and ground.

A Novel Ship Detection Method Based on Gradient and Integral Feature for Single-Polarization Synthetic Aperture Radar Imagery

Directory of Open Access Journals (Sweden)

Hao Shi

2018-02-01

Full Text Available With the rapid development of remote sensing technologies, SAR satellites like China’s Gaofen-3 satellite have more imaging modes and higher resolution. With the availability of high-resolution SAR images, automatic ship target detection has become an important topic in maritime research. In this paper, a novel ship detection method based on gradient and integral features is proposed. This method is mainly composed of three steps. First, in the preprocessing step, a filter is employed to smooth the clutters and the smoothing effect can be adaptive adjusted according to the statistics information of the sub-window. Thus, it can retain details while achieving noise suppression. Second, in the candidate area extraction, a sea-land segmentation method based on gradient enhancement is presented. The integral image method is employed to accelerate computation. Finally, in the ship target identification step, a feature extraction strategy based on Haar-like gradient information and a Radon transform is proposed. This strategy decreases the number of templates found in traditional Haar-like methods. Experiments were performed using Gaofen-3 single-polarization SAR images, and the results showed that the proposed method has high detection accuracy and rapid computational efficiency. In addition, this method has the potential for on-board processing.

Analysis of Artificial Neural Network Backpropagation Using Conjugate Gradient Fletcher Reeves In The Predicting Process

Science.gov (United States)

Wanto, Anjar; Zarlis, Muhammad; Sawaluddin; Hartama, Dedy

2017-12-01

Backpropagation is a good artificial neural network algorithm used to predict, one of which is to predict the rate of Consumer Price Index (CPI) based on the foodstuff sector. While conjugate gradient fletcher reeves is a suitable optimization method when juxtaposed with backpropagation method, because this method can shorten iteration without reducing the quality of training and testing result. Consumer Price Index (CPI) data that will be predicted to come from the Central Statistics Agency (BPS) Pematangsiantar. The results of this study will be expected to contribute to the government in making policies to improve economic growth. In this study, the data obtained will be processed by conducting training and testing with artificial neural network backpropagation by using parameter learning rate 0,01 and target error minimum that is 0.001-0,09. The training network is built with binary and bipolar sigmoid activation functions. After the results with backpropagation are obtained, it will then be optimized using the conjugate gradient fletcher reeves method by conducting the same training and testing based on 5 predefined network architectures. The result, the method used can increase the speed and accuracy result.

Base stock policies with degraded service to larger orders

DEFF Research Database (Denmark)

Du, Bisheng; Larsen, Christian

We study an inventory system controlled by a base stock policy assuming a compound renewal demand process. We extend the base stock policy by incorporating rules for degrading the service of larger orders. Two specific rules are considered, denoted Postpone(q,t) and Split(q), respectively. The aim...... of using these rules is to achieve a given order fill rate of the regular orders (those of size less than or equal to the parameter q) having less inventory. We develop mathematical expressions for the performance measures order fill rate (of the regular orders) and average on-hand inventory level. Based...

Unimodal and crossmodal gradients of spatial attention

DEFF Research Database (Denmark)

Föcker, J.; Hötting, K.; Gondan, Matthias

2010-01-01

Behavioral and event-related potential (ERP) studies have shown that spatial attention is gradually distributed around the center of the attentional focus. The present study compared uni- and crossmodal gradients of spatial attention to investigate whether the orienting of auditory and visual...... spatial attention is based on modality specific or supramodal representations of space. Auditory and visual stimuli were presented from five speaker locations positioned in the right hemifield. Participants had to attend to the innermost or outmost right position in order to detect either visual...... or auditory deviant stimuli. Detection rates and event-related potentials (ERPs) indicated that spatial attention is distributed as a gradient. Unimodal spatial ERP gradients correlated with the spatial resolution of the modality. Crossmodal spatial gradients were always broader than the corresponding...

Penalty Algorithm Based on Conjugate Gradient Method for Solving Portfolio Management Problem

Directory of Open Access Journals (Sweden)

Wang YaLin

2009-01-01

Full Text Available A new approach was proposed to reformulate the biobjectives optimization model of portfolio management into an unconstrained minimization problem, where the objective function is a piecewise quadratic polynomial. We presented some properties of such an objective function. Then, a class of penalty algorithms based on the well-known conjugate gradient methods was developed to find the solution of portfolio management problem. By implementing the proposed algorithm to solve the real problems from the stock market in China, it was shown that this algorithm is promising.

Conditioning the full-waveform inversion gradient to welcome anisotropy

KAUST Repository

Alkhalifah, Tariq Ali

2015-04-23

Multiparameter full-waveform inversion (FWI) suffers from complex nonlinearity in the objective function, compounded by the eventual trade-off between the model parameters. A hierarchical approach based on frequency and arrival time data decimation to maneuver the complex nonlinearity associated with this problem usually falls short in anisotropic media. In place of data decimation, I use a model gradient filter approach to access the parts of the gradient more suitable to combat the potential nonlinearity and parameter trade-off. The filter is based on representing the gradient in the time-lag normalized domain, in which small scattering-angles of the gradient update are initially muted out. The model update hierarchical filtering strategy include applying varying degrees of filtering to the different anisotropic parameter updates, a feature not easily accessible to simple data decimation. Using FWI and reflection-based FWI, when the modeled data are obtained with the single-scattering theory, allows access to additional low model wavenumber components. Combining such access to wavenumbers with scattering-angle filters applied to the individual parameter gradients allows for multiple strategies to avoid complex FWI nonlinearity as well as the parameter trade-off.

Advancing team-based primary health care: a comparative analysis of policies in western Canada.

Science.gov (United States)

Suter, Esther; Mallinson, Sara; Misfeldt, Renee; Boakye, Omenaa; Nasmith, Louise; Wong, Sabrina T

2017-07-17

We analyzed and compared primary health care (PHC) policies in British Columbia, Alberta and Saskatchewan to understand how they inform the design and implementation of team-based primary health care service delivery. The goal was to develop policy imperatives that can advance team-based PHC in Canada. We conducted comparative case studies (n = 3). The policy analysis included: Context review: We reviewed relevant information (2007 to 2014) from databases and websites. Policy review and comparative analysis: We compared and contrasted publically available PHC policies. Key informant interviews: Key informants (n = 30) validated narratives prepared from the comparative analysis by offering contextual information on potential policy imperatives. Advisory group and roundtable: An expert advisory group guided this work and a key stakeholder roundtable event guided prioritization of policy imperatives. The concept of team-based PHC varies widely across and within the three provinces. We noted policy gaps related to team configuration, leadership, scope of practice, role clarity and financing of team-based care; few policies speak explicitly to monitoring and evaluation of team-based PHC. We prioritized four policy imperatives: (1) alignment of goals and policies at different system levels; (2) investment of resources for system change; (3) compensation models for all members of the team; and (4) accountability through collaborative practice metrics. Policies supporting team-based PHC have been slow to emerge, lacking a systematic and coordinated approach. Greater alignment with specific consideration of financing, reimbursement, implementation mechanisms and performance monitoring could accelerate systemic transformation by removing some well-known barriers to team-based care.

Mediated Ciphertext-Policy Attribute-Based Encryption and Its Application

NARCIS (Netherlands)

Ibraimi, L.; Petkovic, M.; Nikova, S.I.; Hartel, Pieter H.; Jonker, Willem; Youm, Heung Youl; Yung, Moti

2009-01-01

In Ciphertext-Policy Attribute-Based Encryption (CP-ABE), a user secret key is associated with a set of attributes, and the ciphertext is associated with an access policy over attributes. The user can decrypt the ciphertext if and only if the attribute set of his secret key satisfies the access

Nonlinear conjugate gradient methods in micromagnetics

Directory of Open Access Journals (Sweden)

J. Fischbacher

2017-04-01

Full Text Available Conjugate gradient methods for energy minimization in micromagnetics are compared. The comparison of analytic results with numerical simulation shows that standard conjugate gradient method may fail to produce correct results. A method that restricts the step length in the line search is introduced, in order to avoid this problem. When the step length in the line search is controlled, conjugate gradient techniques are a fast and reliable way to compute the hysteresis properties of permanent magnets. The method is applied to investigate demagnetizing effects in NdFe12 based permanent magnets. The reduction of the coercive field by demagnetizing effects is μ0ΔH = 1.4 T at 450 K.

Enhanced sensitivity of DNA- and rRNA-based stable isotope probing by fractionation and quantitative analysis of isopycnic centrifugation gradients.

Science.gov (United States)

Lueders, Tillmann; Manefield, Mike; Friedrich, Michael W

2004-01-01

Stable isotope probing (SIP) of nucleic acids allows the detection and identification of active members of natural microbial populations that are involved in the assimilation of an isotopically labelled compound into nucleic acids. SIP is based on the separation of isotopically labelled DNA or rRNA by isopycnic density gradient centrifugation. We have developed a highly sensitive protocol for the detection of 'light' and 'heavy' nucleic acids in fractions of centrifugation gradients. It involves the fluorometric quantification of total DNA or rRNA, and the quantification of either 16S rRNA genes or 16S rRNA in gradient fractions by real-time PCR with domain-specific primers. Using this approach, we found that fully 13C-labelled DNA or rRNA of Methylobacterium extorquens was quantitatively resolved from unlabelled DNA or rRNA of Methanosarcina barkeri by cesium chloride or cesium trifluoroacetate density gradient centrifugation respectively. However, a constant low background of unspecific nucleic acids was detected in all DNA or rRNA gradient fractions, which is important for the interpretation of environmental SIP results. Consequently, quantitative analysis of gradient fractions provides a higher precision and finer resolution for retrieval of isotopically enriched nucleic acids than possible using ethidium bromide or gradient fractionation combined with fingerprinting analyses. This is a prerequisite for the fine-scale tracing of microbial populations metabolizing 13C-labelled compounds in natural ecosystems.

Conditioning the full waveform inversion gradient to welcome anisotropy

KAUST Repository

Alkhalifah, Tariq Ali

2014-01-01

Multi-parameter full waveform inversion (FWI) suffers from the complex nonlinearity in the objective function, compounded by the eventual tradeoff between the model parameters. A hierarchical approach based on frequency and arrival time data decimation to maneuver the complex nonlinearity associated with this problem usually falls short in anisotropic media. In place of data decimation, I use a model gradient filter approach to access the parts of the gradient more suitable to combat the potential nonlinearity and parameter trade off. The filter is based on representing the gradient in the time-lag normalized domain in which the small scattering angles of the gradient update is initially muted out. A model update hierarchical filtering strategy includes applying varying degree of filtering to the different parameter updates. A feature not easily accessible to simple data decimation. Using both FWI and reection based FWI (RFWI), two strategies to combat the tradeoff between anisotropic parameters are outlined.

Conditioning the full waveform inversion gradient to welcome anisotropy

KAUST Repository

Alkhalifah, Tariq Ali

2014-08-05

Multi-parameter full waveform inversion (FWI) suffers from the complex nonlinearity in the objective function, compounded by the eventual tradeoff between the model parameters. A hierarchical approach based on frequency and arrival time data decimation to maneuver the complex nonlinearity associated with this problem usually falls short in anisotropic media. In place of data decimation, I use a model gradient filter approach to access the parts of the gradient more suitable to combat the potential nonlinearity and parameter trade off. The filter is based on representing the gradient in the time-lag normalized domain in which the small scattering angles of the gradient update is initially muted out. A model update hierarchical filtering strategy includes applying varying degree of filtering to the different parameter updates. A feature not easily accessible to simple data decimation. Using both FWI and reection based FWI (RFWI), two strategies to combat the tradeoff between anisotropic parameters are outlined.

Role of spatial averaging in multicellular gradient sensing.

Science.gov (United States)

Smith, Tyler; Fancher, Sean; Levchenko, Andre; Nemenman, Ilya; Mugler, Andrew

2016-05-20

Gradient sensing underlies important biological processes including morphogenesis, polarization, and cell migration. The precision of gradient sensing increases with the length of a detector (a cell or group of cells) in the gradient direction, since a longer detector spans a larger range of concentration values. Intuition from studies of concentration sensing suggests that precision should also increase with detector length in the direction transverse to the gradient, since then spatial averaging should reduce the noise. However, here we show that, unlike for concentration sensing, the precision of gradient sensing decreases with transverse length for the simplest gradient sensing model, local excitation-global inhibition. The reason is that gradient sensing ultimately relies on a subtraction of measured concentration values. While spatial averaging indeed reduces the noise in these measurements, which increases precision, it also reduces the covariance between the measurements, which results in the net decrease in precision. We demonstrate how a recently introduced gradient sensing mechanism, regional excitation-global inhibition (REGI), overcomes this effect and recovers the benefit of transverse averaging. Using a REGI-based model, we compute the optimal two- and three-dimensional detector shapes, and argue that they are consistent with the shapes of naturally occurring gradient-sensing cell populations.

Ultimate gradient in solid-state accelerators

International Nuclear Information System (INIS)

Whittum, D.H.

1998-08-01

The authors recall the motivation for research in high-gradient acceleration and the problems posed by a compact collider. They summarize the phenomena known to appear in operation of a solid-state structure with large fields, and research relevant to the question of the ultimate gradient. They take note of new concepts, and examine one in detail, a miniature particle accelerator based on an active millimeter-wave circuit and parallel particle beams

Strengthening Science-based Environmental Policy Development in ...

International Development Research Centre (IDRC) Digital Library (Canada)

Strengthening Science-based Environmental Policy Development in Burma's Democratic ... IDRC is providing funding to Simon Fraser University to support a network of ... The project will also encourage and assist in the creation of a business ...

Global correlation imaging of magnetic total field gradients

International Nuclear Information System (INIS)

Guo, Lianghui; Meng, Xiaohong; Shi, Lei

2012-01-01

Firstly we introduce the correlation imaging approach for the x-, y- and z-gradients of a magnetic total field anomaly for deriving the distribution of equivalent magnetic sources of the subsurface. In this approach, the subsurface space is divided into a regular grid, and then a correlation coefficient function is computed at each grid node, based on the cross-correlation between the x-gradient (or y-gradient or z-gradient) of the observed magnetic total field anomaly and the x-gradient (or y-gradient or z-gradient) of the theoretical magnetic total field anomaly due to a magnetic dipole. The resultant correlation coefficient is used to describe the probability of a magnetic dipole occurring at the node. We then define a global correlation coefficient function for comprehensively delineating the probability of an occurrence of a magnetic dipole, which takes, at each node, the maximum positive value of the corresponding correlation coefficient function of the three gradients. We finally test the approach both on synthetic data and real data from a metallic deposit area in the middle-lower reaches of the Yangtze River, China. (paper)

Full waveform inversion based on the optimized gradient and its spectral implementation

KAUST Repository

Wu, Zedong

2014-01-01

Full waveform inversion (FWI) despite it\\'s potential suffers from the ability to converge to the desired solution due to the high nonlinearity of the objective function at conventional seismic frequencies. Even if frequencies necessary for the convergence are available, the high number of iterations required to approach a solution renders FWI as very expensive (especially in 3D). A spectral implementation in which the wavefields are extrapolated and gradients are calculated in the wavenumber domain allows for a cleaner more efficient implementation (no finite difference dispersion errors). In addition, we use not only an up and down going wavefield decomposition of the gradient to access the smooth background update, but also a right and left propagation decomposition to allow us to do that for large dips. To insure that the extracted smooth component of the gradient has the right decent direction, we solve an optimization problem to search for the smoothest component that provides a negative (decent) gradient. Application to the Marmousi model shows that this approach works well with linear increasing initial velocity model and data with frequencies above 2Hz.

Design of LED projector based on gradient-index lens

Science.gov (United States)

Qian, Liyong; Zhu, Xiangbing; Cui, Haitian; Wang, Yuanhang

2018-01-01

In this study, a new type of projector light path is designed to eliminate the deficits of existing projection systems, such as complex structure and low collection efficiency. Using a three-color LED array as the lighting source, by means of the special optical properties of a gradient-index lens, the complex structure of the traditional projector is simplified. Traditional components, such as the color wheel, relay lens, and mirror, become unnecessary. In this way, traditional problems, such as low utilization of light energy and loss of light energy, are solved. With the help of Zemax software, the projection lens is optimized. The optimized projection lens, LED, gradient-index lens, and digital micromirror device are imported into Tracepro. The ray tracing results show that both the utilization of light energy and the uniformity are improved significantly.

Development of evidence-based health policy documents in developing countries: a case of Iran.

Science.gov (United States)

Imani-Nasab, Mohammad Hasan; Seyedin, Hesam; Majdzadeh, Reza; Yazdizadeh, Bahareh; Salehi, Masoud

2014-02-07

Evidence-based policy documents that are well developed by senior civil servants and are timely available can reduce the barriers to evidence utilization by health policy makers. This study examined the barriers and facilitators in developing evidence-based health policy documents from the perspective of their producers in a developing country. In a qualitative study with a framework analysis approach, we conducted semi-structured interviews using purposive and snowball sampling. A qualitative analysis software (MAXQDA-10) was used to apply the codes and manage the data. This study was theory-based and the results were compared to exploratory studies about the factors influencing evidence-based health policy-making. 18 codes and three main themes of behavioral, normative, and control beliefs were identified. Factors that influence the development of evidence-based policy documents were identified by the participants: behavioral beliefs included quality of policy documents, use of resources, knowledge and innovation, being time-consuming and contextualization; normative beliefs included policy authorities, policymakers, policy administrators, and co-workers; and control beliefs included recruitment policy, performance management, empowerment, management stability, physical environment, access to evidence, policy making process, and effect of other factors. Most of the cited barriers to the development of evidence-based policy were related to control beliefs, i.e. barriers at the organizational and health system levels. This study identified the factors that influence the development of evidence-based policy documents based on the components of the theory of planned behavior. But in exploratory studies on evidence utilization by health policymakers, the identified factors were only related to control behaviors. This suggests that the theoretical approach may be preferable to the exploratory approach in identifying the barriers and facilitators of a behavior.

Coreless Concept for High Gradient Induction Cell

International Nuclear Information System (INIS)

Krasnykh, Anatoly

2008-01-01

An induction linac cell for a high gradient is discussed. The proposed solid state coreless approach for the induction linac topology (SLIM(reg s ign)) is based on nanosecond mode operation. This mode may have an acceleration gradient comparable with gradients of rf- accelerator structures. The discussed induction system has the high electric efficiency. The key elements are a solid state semiconductor switch and a high electric density dielectric with a thin section length. The energy in the induction system is storied in the magnetic field. The nanosecond current break-up produces the high voltage. The induced voltage is used for acceleration. This manner of an operation allows the use of low voltage elements in the booster part and achieves a high accelerating gradient. The proposed topology was tested in POP (proof of principle) experiments

Quasi Gradient Projection Algorithm for Sparse Reconstruction in Compressed Sensing

Directory of Open Access Journals (Sweden)

Xin Meng

2014-02-01

Full Text Available Compressed sensing is a novel signal sampling theory under the condition that the signal is sparse or compressible. The existing recovery algorithms based on the gradient projection can either need prior knowledge or recovery the signal poorly. In this paper, a new algorithm based on gradient projection is proposed, which is referred as Quasi Gradient Projection. The algorithm presented quasi gradient direction and two step sizes schemes along this direction. The algorithm doesn’t need any prior knowledge of the original signal. Simulation results demonstrate that the presented algorithm cans recovery the signal more correctly than GPSR which also don’t need prior knowledge. Meanwhile, the algorithm has a lower computation complexity.

Full magnetic gradient tensor from triaxial aeromagnetic gradient measurements: Calculation and application

Science.gov (United States)

Luo, Yao; Wu, Mei-Ping; Wang, Ping; Duan, Shu-Ling; Liu, Hao-Jun; Wang, Jin-Long; An, Zhan-Feng

2015-09-01

The full magnetic gradient tensor (MGT) refers to the spatial change rate of the three field components of the geomagnetic field vector along three mutually orthogonal axes. The tensor is of use to geological mapping, resources exploration, magnetic navigation, and others. However, it is very difficult to measure the full magnetic tensor gradient using existing engineering technology. We present a method to use triaxial aeromagnetic gradient measurements for deriving the full MGT. The method uses the triaxial gradient data and makes full use of the variation of the magnetic anomaly modulus in three dimensions to obtain a self-consistent magnetic tensor gradient. Numerical simulations show that the full MGT data obtained with the proposed method are of high precision and satisfy the requirements of data processing. We selected triaxial aeromagnetic gradient data from the Hebei Province for calculating the full MGT. Data processing shows that using triaxial tensor gradient data allows to take advantage of the spatial rate of change of the total field in three dimensions and suppresses part of the independent noise in the aeromagnetic gradient. The calculated tensor components have improved resolution, and the transformed full tensor gradient satisfies the requirement of geological mapping and interpretation.

School-based obesity policy, social capital, and gender differences in weight control behaviors.

Science.gov (United States)

Zhu, Ling; Thomas, Breanca

2013-06-01

We examined the associations among school-based obesity policies, social capital, and adolescents' self-reported weight control behaviors, focusing on how the collective roles of community and adopted policies affect gender groups differently. We estimated state-level ecologic models using 1-way random effects seemingly unrelated regressions derived from panel data for 43 states from 1991 to 2009, which we obtained from the Centers for Disease Control and Prevention's Youth Risk Behavior Surveillance System. We used multiplicative interaction terms to assess how social capital moderates the effects of school-based obesity policies. School-based obesity policies in active communities were mixed in improving weight control behaviors. They increased both healthy and unhealthy weight control behaviors among boys but did not increase healthy weight control behaviors among girls. Social capital is an important contextual factor that conditions policy effectiveness in large contexts. Heterogeneous behavioral responses are associated with both school-based obesity policies and social capital. Building social capital and developing policy programs to balance outcomes for both gender groups may be challenging in managing childhood obesity.

Towards a Demand-Driven Agenda for Place-Based Policies in the EU

DEFF Research Database (Denmark)

Jensen, Camilla

This policy study is the second report on the policy implications of the EU funded project Policy Incentives for the Creation of Knowledge – Methods and Evidence (PICK-ME). All contributions in the project related with place-based policy and cluster building are summarized and reviewed (Work...

Strain gradient plasticity-based modeling of hydrogen environment assisted cracking

DEFF Research Database (Denmark)

Martínez Pañeda, Emilio; Niordson, Christian Frithiof; P. Gangloff, Richard

2016-01-01

Finite element analysis of stress about a blunt crack tip, emphasizing finite strain and phenomenologicaland mechanism-based strain gradient plasticity (SGP) formulations, is integrated with electrochemical assessment of occluded-crack tip hydrogen (H) solubility and two H-decohesion models...... to predict hydrogen environment assisted crack growth properties. SGP elevates crack tip geometrically necessary dislocation density and flow stress, with enhancement declining with increasing alloy strength. Elevated hydrostatic stress promotes high-trapped H concentration for crack tip damage......; it is imperative to account for SGP in H cracking models. Predictions of the threshold stress intensity factor and H-diffusion limited Stage II crack growth rate agree with experimental data for a high strength austenitic Ni-Cusuperalloy (Monel®K-500) and two modern ultra-high strength martensitic steels (Aer...

Computational Strain Gradient Crystal Plasticity

DEFF Research Database (Denmark)

Niordson, Christian Frithiof; Kysar, Jeffrey W.

2011-01-01

A model for strain gradient crystal visco-plasticity is formulated along the lines proposed by Fleck andWillis (2009) for isotropic plasticity. Size-effects are included in the model due to the addition of gradient terms in both the free energy as well as through a dissipation potential. A finite...... element solution method is presented, which delivers the slip-rate field and the velocity-field based on two minimum principles. Some plane deformation problems relevant for certain specific orientations of a face centered cubic crystal under plane loading conditions are studied, and effective in......-plane parameters are developed based on the crystallographic properties of the material. The problem of cyclic shear of a single crystal between rigid platens is studied as well as void growth of a cylindrical void....

Development of Evidence-Based Health Policy Documents in Developing Countries: A Case of Iran

Science.gov (United States)

Imani-Nasab, Mohammad Hasan; Seyedin, Hesam; Majdzadeh, Reza; Yazdizadeh, Bahareh; Salehi, Masoud

2014-01-01

Background: Evidence-based policy documents that are well developed by senior civil servants and are timely available can reduce the barriers to evidence utilization by health policy makers. This study examined the barriers and facilitators in developing evidence-based health policy documents from the perspective of their producers in a developing country. Methods: In a qualitative study with a framework analysis approach, we conducted semi-structured interviews using purposive and snowball sampling. A qualitative analysis software (MAXQDA-10) was used to apply the codes and manage the data. This study was theory-based and the results were compared to exploratory studies about the factors influencing evidence-based health policymaking. Results: 18 codes and three main themes of behavioral, normative, and control beliefs were identified. Factors that influence the development of evidence-based policy documents were identified by the participants: behavioral beliefs included quality of policy documents, use of resources, knowledge and innovation, being time-consuming and contextualization; normative beliefs included policy authorities, policymakers, policy administrators, and co-workers; and control beliefs included recruitment policy, performance management, empowerment, management stability, physical environment, access to evidence, policy making process, and effect of other factors. Conclusion: Most of the cited barriers to the development of evidence-based policy were related to control beliefs, i.e. barriers at the organizational and health system levels. This study identified the factors that influence the development of evidence-based policy documents based on the components of the theory of planned behavior. But in exploratory studies on evidence utilization by health policymakers, the identified factors were only related to control behaviors. This suggests that the theoretical approach may be preferable to the exploratory approach in identifying the barriers

Subsurface temperatures and geothermal gradients on the north slope of Alaska

Science.gov (United States)

Collett, T.S.; Bird, K.J.; Magoon, L.B.

1993-01-01

On the North Slope of Alaska, geothermal gradient data are available from high-resolution, equilibrated well-bore surveys and from estimates based on well-log identification of the base of ice-bearing permafrost. A total of 46 North Slope wells, considered to be in or near thermal equilibrium, have been surveyed with high-resolution temperatures devices and geothermal gradients can be interpreted directly from these recorded temperature profiles. To augment the limited North Slope temperature data base, a new method of evaluating local geothermal gradients has been developed. In this method, a series of well-log picks for the base of the ice-bearing permafrost from 102 wells have been used, along with regional temperature constants derived from the high-resolution stabilized well-bore temperature surveys, to project geothermal gradients. Geothermal gradients calculated from the high-resolution temperature surveys generally agree with those projected from known ice-bearing permafrost depths over most of the North Slope. Values in the ice-bearing permafrost range from ??? 1.5??C 100 m in the Prudhoe Bay area to ??? 4.5??C 100 m in the east-central portion of the National Petroleum Reserve in Alaska. Geothermal gradients below the ice-bearing permafrost sequence range from ??? 1.6??C 100 m to ??? 5.2??C 100 m. ?? 1993.

Gradient networks on uncorrelated random scale-free networks

International Nuclear Information System (INIS)

Pan Guijun; Yan Xiaoqing; Huang Zhongbing; Ma Weichuan

2011-01-01

Uncorrelated random scale-free (URSF) networks are useful null models for checking the effects of scale-free topology on network-based dynamical processes. Here, we present a comparative study of the jamming level of gradient networks based on URSF networks and Erdos-Renyi (ER) random networks. We find that the URSF networks are less congested than ER random networks for the average degree (k)>k c (k c ∼ 2 denotes a critical connectivity). In addition, by investigating the topological properties of the two kinds of gradient networks, we discuss the relations between the topological structure and the transport efficiency of the gradient networks. These findings show that the uncorrelated scale-free structure might allow more efficient transport than the random structure.

Systems biology derived source-sink mechanism of BMP gradient formation.

Science.gov (United States)

Zinski, Joseph; Bu, Ye; Wang, Xu; Dou, Wei; Umulis, David; Mullins, Mary C

2017-08-09

A morphogen gradient of Bone Morphogenetic Protein (BMP) signaling patterns the dorsoventral embryonic axis of vertebrates and invertebrates. The prevailing view in vertebrates for BMP gradient formation is through a counter-gradient of BMP antagonists, often along with ligand shuttling to generate peak signaling levels. To delineate the mechanism in zebrafish, we precisely quantified the BMP activity gradient in wild-type and mutant embryos and combined these data with a mathematical model-based computational screen to test hypotheses for gradient formation. Our analysis ruled out a BMP shuttling mechanism and a bmp transcriptionally-informed gradient mechanism. Surprisingly, rather than supporting a counter-gradient mechanism, our analyses support a fourth model, a source-sink mechanism, which relies on a restricted BMP antagonist distribution acting as a sink that drives BMP flux dorsally and gradient formation. We measured Bmp2 diffusion and found that it supports the source-sink model, suggesting a new mechanism to shape BMP gradients during development.

Moving force identification based on modified preconditioned conjugate gradient method

Science.gov (United States)

Chen, Zhen; Chan, Tommy H. T.; Nguyen, Andy

2018-06-01

This paper develops a modified preconditioned conjugate gradient (M-PCG) method for moving force identification (MFI) by improving the conjugate gradient (CG) and preconditioned conjugate gradient (PCG) methods with a modified Gram-Schmidt algorithm. The method aims to obtain more accurate and more efficient identification results from the responses of bridge deck caused by vehicles passing by, which are known to be sensitive to ill-posed problems that exist in the inverse problem. A simply supported beam model with biaxial time-varying forces is used to generate numerical simulations with various analysis scenarios to assess the effectiveness of the method. Evaluation results show that regularization matrix L and number of iterations j are very important influence factors to identification accuracy and noise immunity of M-PCG. Compared with the conventional counterpart SVD embedded in the time domain method (TDM) and the standard form of CG, the M-PCG with proper regularization matrix has many advantages such as better adaptability and more robust to ill-posed problems. More importantly, it is shown that the average optimal numbers of iterations of M-PCG can be reduced by more than 70% compared with PCG and this apparently makes M-PCG a preferred choice for field MFI applications.

On Scalable Deep Learning and Parallelizing Gradient Descent

CERN Document Server

AUTHOR|(CDS)2129036; Möckel, Rico; Baranowski, Zbigniew; Canali, Luca

Speeding up gradient based methods has been a subject of interest over the past years with many practical applications, especially with respect to Deep Learning. Despite the fact that many optimizations have been done on a hardware level, the convergence rate of very large models remains problematic. Therefore, data parallel methods next to mini-batch parallelism have been suggested to further decrease the training time of parameterized models using gradient based methods. Nevertheless, asynchronous optimization was considered too unstable for practical purposes due to a lacking understanding of the underlying mechanisms. Recently, a theoretical contribution has been made which defines asynchronous optimization in terms of (implicit) momentum due to the presence of a queuing model of gradients based on past parameterizations. This thesis mainly builds upon this work to construct a better understanding why asynchronous optimization shows proportionally more divergent behavior when the number of parallel worker...

The effect of water uptake gradient in membrane electrode assembly on fuel cell performance

Energy Technology Data Exchange (ETDEWEB)

Fujita, H., E-mail: hajime.phy@gmail.co [Research Institute for Science Engineering, Waseda University, 103, R.J.Shillman Hall, 3-14-9, Okubo, Shinjuku, Tokyo 169-0072 (Japan); Shiraki, F.; Oshima, Y.; Tatsumi, T.; Yoshikawa, T.; Sasaki, T. [Research Institute for Science Engineering, Waseda University, 103, R.J.Shillman Hall, 3-14-9, Okubo, Shinjuku, Tokyo 169-0072 (Japan); Oshima, A. [Institute for Scientific and Industrial Research, Osaka University, 8-1 Mihogaoka, Ibaraki, Osaka 567-0047 (Japan); Washio, M. [Research Institute for Science Engineering, Waseda University, 103, R.J.Shillman Hall, 3-14-9, Okubo, Shinjuku, Tokyo 169-0072 (Japan)

2011-02-15

Novel proton exchange membranes (PEMs) with functionally gradient ionic sites were fabricated utilizing low energy electron beam (EB) irradiations. The low energy electron beam irradiation to polymer membranes possessed the property of gradient energy deposition in the membrane thickness direction. In the process of EB grafting of styrene onto base films, selective ranges of the gradient energy deposition were used. Micro FT-IR spectra showed that the simulated energy deposition of EB irradiation to base polymer membranes in the thickness direction corresponded to the amount of styrene grafted onto EB-irradiated films. After sulfonation, a functionally gradient ionic site PEM (gradient-PEM) was prepared, corresponding to EB depth-dose profile. The functionally gradients of ionic sites in the gradient-PEM and flat-PEM were evaluated with XPS and SEM-EDX. The results of XPS and SEM-EDX suggest that the prepared gradient-PEM had a gradient sulfonated acid groups. In addition, the polarization performance of MEA based on gradient-PEM was improved in high current density. It was thought that water uptake gradient could have a function to prevent flooding in the MEA during FC operation. Thus, the functionally gradient-PEMs could be a promising solution to manage the water behavior in MEA.

Age replacement policy based on imperfect repair with random probability

International Nuclear Information System (INIS)

Lim, J.H.; Qu, Jian; Zuo, Ming J.

2016-01-01

In most of literatures of age replacement policy, failures before planned replacement age can be either minimally repaired or perfectly repaired based on the types of failures, cost for repairs and so on. In this paper, we propose age replacement policy based on imperfect repair with random probability. The proposed policy incorporates the case that such intermittent failure can be either minimally repaired or perfectly repaired with random probabilities. The mathematical formulas of the expected cost rate per unit time are derived for both the infinite-horizon case and the one-replacement-cycle case. For each case, we show that the optimal replacement age exists and is finite. - Highlights: • We propose a new age replacement policy with random probability of perfect repair. • We develop the expected cost per unit time. • We discuss the optimal age for replacement minimizing the expected cost rate.

Missing value imputation in DNA microarrays based on conjugate gradient method.

Science.gov (United States)

Dorri, Fatemeh; Azmi, Paeiz; Dorri, Faezeh

2012-02-01

Analysis of gene expression profiles needs a complete matrix of gene array values; consequently, imputation methods have been suggested. In this paper, an algorithm that is based on conjugate gradient (CG) method is proposed to estimate missing values. k-nearest neighbors of the missed entry are first selected based on absolute values of their Pearson correlation coefficient. Then a subset of genes among the k-nearest neighbors is labeled as the best similar ones. CG algorithm with this subset as its input is then used to estimate the missing values. Our proposed CG based algorithm (CGimpute) is evaluated on different data sets. The results are compared with sequential local least squares (SLLSimpute), Bayesian principle component analysis (BPCAimpute), local least squares imputation (LLSimpute), iterated local least squares imputation (ILLSimpute) and adaptive k-nearest neighbors imputation (KNNKimpute) methods. The average of normalized root mean squares error (NRMSE) and relative NRMSE in different data sets with various missing rates shows CGimpute outperforms other methods. Copyright © 2011 Elsevier Ltd. All rights reserved.

Improved incorporation of strain gradient elasticity in the flexoelectricity based energy harvesting from nanobeams

Science.gov (United States)

Zhou, Yarong; Yang, Xu; Pan, Dongmei; Wang, Binglei

2018-04-01

Flexoelectricity, the coupling of strain gradient and polarization, exists in all the dielectric materials and numerous models have been proposed to study this mechanism. However, the contribution of strain gradient elasticity has typically been underestimated. In this work, inspired by the one-length scale parameter model developed by Deng et al. [19], we incorporate three length-scale parameters to carefully capture the contribution of the purely mechanical strain gradients on flexoelectricity. This three-parameter model is more flexible and could be applied to investigate the flexoelectricity in a wide range of complicated deformations. Accordingly, we carry out our analysis by studying a dielectric nanobeam under different boundary conditions. We show that the strain gradient elasticity and flexoelectricity have apparent size effects and significant influence on the electromechanical response. In particular, the strain gradient effects could significantly reduce the energy efficiency, indicating their importance and necessity. This work may be helpful in understanding the mechanism of flexoelectricity at the nanoscale and sheds light on the flexoelectricity energy harvesting.

Rank gradient and p-gradient of amalgamated free products and HNN extensions

OpenAIRE

Pappas, Nathaniel

2013-01-01

We calculate the rank gradient and p-gradient of free products, free products with amalgamation over an amenable subgroup, and HNN extensions with an amenable associated subgroup. The notion of cost is used to compute the rank gradient of amalgamated free products and HNN extensions. For the p-gradient the Kurosh subgroup theorems for amalgamated free products and HNN extensions will be used.

A review of Agent Based Modeling for agricultural policy evaluation

NARCIS (Netherlands)

Kremmydas, Dimitris; Athanasiadis, I.N.; Rozakis, Stelios

2018-01-01

Farm level scale policy analysis is receiving increased attention due to a changing agricultural policy orientation. Agent based models (ABM) are farm level models that have appeared in the end of 1990's, having several differences from traditional farm level models, like the consideration of

Designing optimal nanofocusing with a gradient hyperlens

Directory of Open Access Journals (Sweden)

Shen Lian

2017-11-01

Full Text Available We report the design of a high-throughput gradient hyperbolic lenslet built with real-life materials and capable of focusing a beam into a deep sub-wavelength spot of λ/23. This efficient design is achieved through high-order transformation optics and circular effective-medium theory (CEMT, which are used to engineer the radially varying anisotropic artificial material based on the thin alternating cylindrical metal and dielectric layers. The radial gradient of the effective anisotropic optical constants allows for matching the impedances at the input and output interfaces, drastically improving the throughput of the lenslet. However, it is the use of the zeroth-order CEMT that enables the practical realization of a gradient hyperlens with realistic materials. To illustrate the importance of using the CEMT versus the conventional planar effective-medium theory (PEMT for cylindrical anisotropic systems, such as our hyperlens, both the CEMT and PEMT are adopted to design gradient hyperlenses with the same materials and order of elemental layers. The CEMT- and PEMT-based designs show similar performance if the number of metal-dielectric binary layers is sufficiently large (9+ pairs and if the layers are sufficiently thin. However, for the manufacturable lenses with realistic numbers of layers (e.g. five pairs and thicknesses, the performance of the CEMT design continues to be practical, whereas the PEMT-based design stops working altogether. The accurate design of transformation optics-based layered cylindrical devices enabled by CEMT allow for a new class of robustly manufacturable nanophotonic systems, even with relatively thick layers of real-life materials.

Arbitrary magnetic field gradient waveform correction using an impulse response based pre-equalization technique.

Science.gov (United States)

Goora, Frédéric G; Colpitts, Bruce G; Balcom, Bruce J

2014-01-01

The time-varying magnetic fields used in magnetic resonance applications result in the induction of eddy currents on conductive structures in the vicinity of both the sample under investigation and the gradient coils. These eddy currents typically result in undesired degradations of image quality for MRI applications. Their ubiquitous nature has resulted in the development of various approaches to characterize and minimize their impact on image quality. This paper outlines a method that utilizes the magnetic field gradient waveform monitor method to directly measure the temporal evolution of the magnetic field gradient from a step-like input function and extracts the system impulse response. With the basic assumption that the gradient system is sufficiently linear and time invariant to permit system theory analysis, the impulse response is used to determine a pre-equalized (optimized) input waveform that provides a desired gradient response at the output of the system. An algorithm has been developed that calculates a pre-equalized waveform that may be accurately reproduced by the amplifier (is physically realizable) and accounts for system limitations including system bandwidth, amplifier slew rate capabilities, and noise inherent in the initial measurement. Significant improvements in magnetic field gradient waveform fidelity after pre-equalization have been realized and are summarized. Copyright © 2013 Elsevier Inc. All rights reserved.

Fifty shades of gradients: does the pressure gradient in venous sinus stenting for idiopathic intracranial hypertension matter? A systematic review.

Science.gov (United States)

McDougall, Cameron M; Ban, Vin Shen; Beecher, Jeffrey; Pride, Lee; Welch, Babu G

2018-03-02

OBJECTIVE The role of venous sinus stenting (VSS) for idiopathic intracranial hypertension (IIH) is not well understood. The aim of this systematic review is to attempt to identify subsets of patients with IIH who will benefit from VSS based on the pressure gradients of their venous sinus stenosis. METHODS MEDLINE/PubMed was searched for studies reporting venous pressure gradients across the stenotic segment of the venous sinus, pre- and post-stent pressure gradients, and clinical outcomes after VSS. Findings are reported according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. RESULTS From 32 eligible studies, a total of 186 patients were included in the analysis. Patients who had favorable outcomes had higher mean pressure gradients (22.8 ± 11.5 mm Hg vs 17.4 ± 8.0 mm Hg, p = 0.033) and higher changes in pressure gradients after stent placement (19.4 ± 10.0 mm Hg vs 12.0 ± 6.0 mm Hg, p = 0.006) compared with those with unfavorable outcomes. The post-stent pressure gradients between the 2 groups were not significantly different (2.8 ± 4.0 mm Hg vs 2.7 ± 2.0 mm Hg, p = 0.934). In a multivariate stepwise logistic regression controlling for age, sex, body mass index, CSF opening pressure, pre-stent pressure gradient, and post-stent pressure gradient, the change in pressure gradient with stent placement was found to be an independent predictor of favorable outcome (p = 0.028). Using a pressure gradient of 21 as a cutoff, 81/86 (94.2%) of patients with a gradient > 21 achieved favorable outcomes, compared with 82/100 (82.0%) of patients with a gradient ≤ 21 (p = 0.022). CONCLUSIONS There appears to be a relationship between the pressure gradient of venous sinus stenosis and the success of VSS in IIH. A randomized controlled trial would help elucidate this relationship and potentially guide patient selection.

Validation for 2D/3D registration II: The comparison of intensity- and gradient-based merit functions using a new gold standard data set

International Nuclear Information System (INIS)

Gendrin, Christelle; Markelj, Primoz; Pawiro, Supriyanto Ardjo; Spoerk, Jakob; Bloch, Christoph; Weber, Christoph; Figl, Michael; Bergmann, Helmar; Birkfellner, Wolfgang; Likar, Bostjan; Pernus, Franjo

2011-01-01

Purpose: A new gold standard data set for validation of 2D/3D registration based on a porcine cadaver head with attached fiducial markers was presented in the first part of this article. The advantage of this new phantom is the large amount of soft tissue, which simulates realistic conditions for registration. This article tests the performance of intensity- and gradient-based algorithms for 2D/3D registration using the new phantom data set. Methods: Intensity-based methods with four merit functions, namely, cross correlation, rank correlation, correlation ratio, and mutual information (MI), and two gradient-based algorithms, the backprojection gradient-based (BGB) registration method and the reconstruction gradient-based (RGB) registration method, were compared. Four volumes consisting of CBCT with two fields of view, 64 slice multidetector CT, and magnetic resonance-T1 weighted images were registered to a pair of kV x-ray images and a pair of MV images. A standardized evaluation methodology was employed. Targets were evenly spread over the volumes and 250 starting positions of the 3D volumes with initial displacements of up to 25 mm from the gold standard position were calculated. After the registration, the displacement from the gold standard was retrieved and the root mean square (RMS), mean, and standard deviation mean target registration errors (mTREs) over 250 registrations were derived. Additionally, the following merit properties were computed: Accuracy, capture range, number of minima, risk of nonconvergence, and distinctiveness of optimum for better comparison of the robustness of each merit. Results: Among the merit functions used for the intensity-based method, MI reached the best accuracy with an RMS mTRE down to 1.30 mm. Furthermore, it was the only merit function that could accurately register the CT to the kV x rays with the presence of tissue deformation. As for the gradient-based methods, BGB and RGB methods achieved subvoxel accuracy (RMS m

An extended discrete gradient formula for oscillatory Hamiltonian systems

International Nuclear Information System (INIS)

Liu Kai; Shi Wei; Wu Xinyuan

2013-01-01

In this paper, incorporating the idea of the discrete gradient method into the extended Runge–Kutta–Nyström integrator, we derive and analyze an extended discrete gradient formula for the oscillatory Hamiltonian system with the Hamiltonian H(p,q)= 1/2 p T p+ 1/2 q T Mq+U(q), where q:R→R d represents generalized positions, p:R→R d represents generalized momenta and M is an element of R dxd is a symmetric and positive semi-definite matrix. The solution of this system is a nonlinear oscillator. Basically, many nonlinear oscillatory mechanical systems with a partitioned Hamiltonian function lend themselves to this approach. The extended discrete gradient formula presented in this paper exactly preserves the energy H(p, q). We derive some properties of the new formula. The convergence is analyzed for the implicit schemes based on the discrete gradient formula, and it turns out that the convergence of the implicit schemes based on the extended discrete gradient formula is independent of ‖M‖, which is a significant property for the oscillatory Hamiltonian system. Thus, it transpires that a larger step size can be chosen for the new energy-preserving schemes than that for the traditional discrete gradient methods when applied to the oscillatory Hamiltonian system. Illustrative examples show the competence and efficiency of the new schemes in comparison with the traditional discrete gradient methods in the scientific literature. (paper)

From theory based policy evaluation to SMART Policy Design: Lessons learned from 20 ex-post evaluations of energy efficiency instruments

International Nuclear Information System (INIS)

Harmelink, Mirjam; Harmsen, Robert; Nilsson, Lars

2007-01-01

This article presents the results of an in-depth ex-post analysis of 20 energy efficiency policy instruments applied across different sectors and countries. Within the AID-EE project, we reconstructed and analysed the implementation process of energy efficiency policy instruments with the aim to identify key factors behind successes and failures. The analysis was performed using a uniform methodology called 'theory based policy evaluation'. With this method the whole implementation process is assessed with the aim to identify: (i) the main hurdles in each step of the implementation process, (ii) key success factors for different types of instruments and (iii) the key indicators that need to be monitored to enable a sound evaluation of the energy efficiency instruments. Our analysis shows that: Energy efficiency policies often lack quantitative targets and clear timeframes; Often policy instruments have multiple and/or unclear objectives; The need for monitoring information does often not have priority in the design phase; For most instruments, monitoring information is collected on a regular basis. However, this information is often insufficient to determine the impact on energy saving, cost-effectiveness and target achievement of an instrument; Monitoring and verification of actual energy savings have a relatively low priority for most of the analyzed instruments. There is no such thing as the 'best' policy instrument. However, typical circumstances in which to apply different types of instruments and generic characteristics that determine success or failure can be identified. Based on the assessments and the experience from applying theory based policy evaluation ex-post, we suggest that this should already be used in the policy formulation and design phase of instruments. We conclude that making policy theory an integral and mandated part of the policy process would facilitate more efficient and effective energy efficiency instruments

GROUP POLICY BASED AUTHENTICATION ON INCOMING CALLS FOR ANDROID SMARTPHONES

OpenAIRE

Sunita M. Kumbhar, Prof. Z.M Shaikh

2016-01-01

The numbers of Smartphone users increasing day by day. Hence, there is need to propose advanced Group Policy based Authentication for incoming calls for Android phone. Android platform provides a variety of functions that support the programming of face recognition, as in image processing. Group policy based authentication scheme increases the security which restricts the access of incoming call form un-authorized user. To solve problems, related to face recognition should be applied in the p...

Stable Computation of the Vertical Gradient of Potential Field Data Based on Incorporating the Smoothing Filters

Science.gov (United States)

Baniamerian, Jamaledin; Liu, Shuang; Abbas, Mahmoud Ahmed

2018-04-01

The vertical gradient is an essential tool in interpretation algorithms. It is also the primary enhancement technique to improve the resolution of measured gravity and magnetic field data, since it has higher sensitivity to changes in physical properties (density or susceptibility) of the subsurface structures than the measured field. If the field derivatives are not directly measured with the gradiometers, they can be calculated from the collected gravity or magnetic data using numerical methods such as those based on fast Fourier transform technique. The gradients behave similar to high-pass filters and enhance the short-wavelength anomalies which may be associated with either small-shallow sources or high-frequency noise content in data, and their numerical computation is susceptible to suffer from amplification of noise. This behaviour can adversely affect the stability of the derivatives in the presence of even a small level of the noise and consequently limit their application to interpretation methods. Adding a smoothing term to the conventional formulation of calculating the vertical gradient in Fourier domain can improve the stability of numerical differentiation of the field. In this paper, we propose a strategy in which the overall efficiency of the classical algorithm in Fourier domain is improved by incorporating two different smoothing filters. For smoothing term, a simple qualitative procedure based on the upward continuation of the field to a higher altitude is introduced to estimate the related parameters which are called regularization parameter and cut-off wavenumber in the corresponding filters. The efficiency of these new approaches is validated by computing the first- and second-order derivatives of noise-corrupted synthetic data sets and then comparing the results with the true ones. The filtered and unfiltered vertical gradients are incorporated into the extended Euler deconvolution to estimate the depth and structural index of a magnetic

Magnetic field of longitudinal gradient bend

Science.gov (United States)

Aiba, Masamitsu; Böge, Michael; Ehrlichman, Michael; Streun, Andreas

2018-06-01

The longitudinal gradient bend is an effective method for reducing the natural emittance in light sources. It is, however, not a common element. We have analyzed its magnetic field and derived a set of formulae. Based on the derivation, we discuss how to model the longitudinal gradient bend in accelerator codes that are used for designing electron storage rings. Strengths of multipole components can also be evaluated from the formulae, and we investigate the impact of higher order multipole components in a very low emittance lattice.

Adaptive Regularization of Neural Networks Using Conjugate Gradient

DEFF Research Database (Denmark)

Goutte, Cyril; Larsen, Jan

1998-01-01

Andersen et al. (1997) and Larsen et al. (1996, 1997) suggested a regularization scheme which iteratively adapts regularization parameters by minimizing validation error using simple gradient descent. In this contribution we present an improved algorithm based on the conjugate gradient technique........ Numerical experiments with feedforward neural networks successfully demonstrate improved generalization ability and lower computational cost...

Variable high gradient permanent magnet quadrupole (QUAPEVA)

Science.gov (United States)

Marteau, F.; Ghaith, A.; N'Gotta, P.; Benabderrahmane, C.; Valléau, M.; Kitegi, C.; Loulergue, A.; Vétéran, J.; Sebdaoui, M.; André, T.; Le Bec, G.; Chavanne, J.; Vallerand, C.; Oumbarek, D.; Cosson, O.; Forest, F.; Jivkov, P.; Lancelot, J. L.; Couprie, M. E.

2017-12-01

Different applications such as laser plasma acceleration, colliders, and diffraction limited light sources require high gradient quadrupoles, with strength that can reach up to 200 T/m for a typical 10 mm bore diameter. We present here a permanent magnet based quadrupole (so-called QUAPEVA) composed of a Halbach ring and surrounded by four permanent magnet cylinders. Its design including magnetic simulation modeling enabling us to reach 201 T/m with a gradient variability of 45% and mechanical issues are reported. Magnetic measurements of seven systems of different lengths are presented and confirmed the theoretical expectations. The variation of the magnetic center while changing the gradient strength is ±10 μm. A triplet of QUAPEVA magnets is used to efficiently focus a beam with large energy spread and high divergence that is generated by a Laser Plasma Acceleration source for a free electron laser demonstration and has enabled us to perform beam based alignment and control the dispersion of the beam.

Inversion gradients for acoustic VTI wavefield tomography

KAUST Repository

Li, Vladimir; Wang, Hui; Tsvankin, Ilya; Dí az, Esteban; Alkhalifah, Tariq Ali

2017-01-01

Wavefield tomography can handle complex subsurface geology better than ray-based techniques and, ultimately, provide a higher resolution. Here, we implement forward and adjoint wavefield extrapolation for VTI (transversely isotropic with a vertical symmetry axis) media using a generalized pseudospectral operator based on a separable approximation for the P-wave dispersion relation. This operator is employed to derive the gradients of the differential semblance optimization (DSO) and modified image-power objective functions. We also obtain the gradient expressions for a data-domain objective function that can more easily incorporate borehole information necessary for stable VTI velocity analysis. These gradients are similar to the ones obtained with a space-time finite-difference (FD) scheme for a system of coupled wave equations but the pseudospectral method is not hampered by the imprint of the shear-wave artifact. Numerical examples also show the potential advantages of the modified image-power objective function in estimating the anellipticity parameter η.

Inversion gradients for acoustic VTI wavefield tomography

KAUST Repository

Li, Vladimir

2017-03-21

Wavefield tomography can handle complex subsurface geology better than ray-based techniques and, ultimately, provide a higher resolution. Here, we implement forward and adjoint wavefield extrapolation for VTI (transversely isotropic with a vertical symmetry axis) media using a generalized pseudospectral operator based on a separable approximation for the P-wave dispersion relation. This operator is employed to derive the gradients of the differential semblance optimization (DSO) and modified image-power objective functions. We also obtain the gradient expressions for a data-domain objective function that can more easily incorporate borehole information necessary for stable VTI velocity analysis. These gradients are similar to the ones obtained with a space-time finite-difference (FD) scheme for a system of coupled wave equations but the pseudospectral method is not hampered by the imprint of the shear-wave artifact. Numerical examples also show the potential advantages of the modified image-power objective function in estimating the anellipticity parameter η.

Realizing IoT service's policy privacy over publish/subscribe-based middleware.

Science.gov (United States)

Duan, Li; Zhang, Yang; Chen, Shiping; Wang, Shiyao; Cheng, Bo; Chen, Junliang

2016-01-01

The publish/subscribe paradigm makes IoT service collaborations more scalable and flexible, due to the space, time and control decoupling of event producers and consumers. Thus, the paradigm can be used to establish large-scale IoT service communication infrastructures such as Supervisory Control and Data Acquisition systems. However, preserving IoT service's policy privacy is difficult in this paradigm, because a classical publisher has little control of its own event after being published; and a subscriber has to accept all the events from the subscribed event type with no choice. Few existing publish/subscribe middleware have built-in mechanisms to address the above issues. In this paper, we present a novel access control framework, which is capable of preserving IoT service's policy privacy. In particular, we adopt the publish/subscribe paradigm as the IoT service communication infrastructure to facilitate the protection of IoT services policy privacy. The key idea in our policy-privacy solution is using a two-layer cooperating method to match bi-directional privacy control requirements: (a) data layer for protecting IoT events; and (b) application layer for preserving the privacy of service policy. Furthermore, the anonymous-set-based principle is adopted to realize the functionalities of the framework, including policy embedding and policy encoding as well as policy matching. Our security analysis shows that the policy privacy framework is Chosen-Plaintext Attack secure. We extend the open source Apache ActiveMQ broker by building into a policy-based authorization mechanism to enforce the privacy policy. The performance evaluation results indicate that our approach is scalable with reasonable overheads.

The Exit Gradient As a Measure of Groundwater Dependency of Watershed Ecosystem Services

Science.gov (United States)

Faulkner, B. R.; Canfield, T. J.; Justin, G. F.

2014-12-01

Flux of groundwater to surface water is often of great interest for the determination of the groundwater dependency of ecosystem services, such as maintenance of wetlands and of baseflow as a contributor to stream channel storage. It is difficult to measure. Most methods are based on coarse mass balance estimates or seepage meters. One drawback of these methods is they are not entirely spatially explicit. The exit gradient is commonly used in engineering studies of hydraulic structures affected by groundwater flow. It can be simply defined in the groundwater modeling context as the ratio of the difference between the computed head and the land surface elevation, for each computational cell, to the thickness of the cell, as it varies in space. When combined with calibrated groundwater flow models, it also has the potential to be useful in watershed scale evaluations of groundwater dependency in a spatially explicit way. We have taken advantage of calibrated models for the Calapooia watershed, Oregon, to map exit gradients for the watershed. Streams in the Calapooia are hydraulically well connected with groundwater. Not surprisingly, we found large variations in exit gradients between wet and dry season model runs, supporting the notion of stream expansion, as observed in the field, which may have a substantial influence on water quality. We have mapped the exit gradients in the wet and dry seasons, and compared them to regions which have been mapped in wetland surveys. Those classified as Palustrine types fell largest in the area of contribution from groundwater. In many cases, substantially high exit gradients, even on average, did not correspond to mapped wetland areas, yet nutrient retention ecosystem services may still be playing a role in these areas. The results also reinforce the notion of the importance of baseflow to maintenance of stream flow, even in the dry summer season in this Temperate/Mediterranean climate. Exit gradient mapping is a simple, yet

Moving Zimbabwe Forward : an Evidence Based Policy Dialogue ...

International Development Research Centre (IDRC) Digital Library (Canada)

Moving Zimbabwe Forward : an Evidence Based Policy Dialogue ... levels of poverty, unemployment, inflation and poor service provision in the areas of education, ... International Water Resources Association, in close collaboration with IDRC, ...

A Path-Based Gradient Projection Algorithm for the Cost-Based System Optimum Problem in Networks with Continuously Distributed Value of Time

Directory of Open Access Journals (Sweden)

Wen-Xiang Wu

2014-01-01

Full Text Available The cost-based system optimum problem in networks with continuously distributed value of time is formulated as a path-based form, which cannot be solved by the Frank-Wolfe algorithm. In light of magnitude improvement in the availability of computer memory in recent years, path-based algorithms have been regarded as a viable approach for traffic assignment problems with reasonably large network sizes. We develop a path-based gradient projection algorithm for solving the cost-based system optimum model, based on Goldstein-Levitin-Polyak method which has been successfully applied to solve standard user equilibrium and system optimum problems. The Sioux Falls network tested is used to verify the effectiveness of the algorithm.

Explanation of L→H mode transition based on gradient stabilization of edge thermal fluctuations

International Nuclear Information System (INIS)

Stacey, W.M.

1996-01-01

A linear analysis of thermal fluctuations, using a fluid model which treats the large radial gradient related phenomena in the plasma edge, leads to a constraint on the temperature and density gradients for stabilization of edge temperature fluctuations. A temperature gradient, or conductive edge heat flux, threshold is identified. It is proposed that the L→H transition takes place when the conductive heat flux to the edge produces a sufficiently large edge temperature gradient to stabilize the edge thermal fluctuations. The consequences following from this mechanism for the L→H transition are in accord with observed phenomena associated with the L→H transition and with the observed parameter dependences of the power threshold. First, a constraint is established on the edge temperature and density gradients that are sufficient for the stability of edge temperature fluctuations. A slab approximation for the thin plasma edge and a fluid model connected to account for the large radial gradients present in the plasma edge are used. Equilibrium solutions are characterized by the value of the density and of its gradient L n -1 double-bond - n -1 , etc. Temperature fluctuations expanded about the equilibrium value are then used in the energy balance equation summed over plasma ions, electrons and impurities to obtain, after linearization, an expression for the growth rate ω of edge localized thermal fluctuations. Thermal stability of the equilibrium solution requires ω ≤ 0, which establishes a constraint that must be satisfied by L n -1 and L T -1 . The limiting value of the constraint (ω = 0) leads to an expression for the minimum value of that is sufficient for thermal stability, for a given value of L T -1. It is found that there is a minimum value of the temperature gradient, (L T -1 ) min that is necessary for a stable solution to exist for any value of L n -1

Economic transition policies in Chinese resource-based cities: An overview of government efforts

International Nuclear Information System (INIS)

Li, Huijuan; Long, Ruyin; Chen, Hong

2013-01-01

Resource-based cities in China have made momentous contributions to the development of the national economy for decades. However, with the depletion of natural resources, their sustainable development is challenging and transition is important. The Chinese government has made great efforts to help resource-based cities. The purpose of this study is to investigate transition policies and their implementation. Firstly, we reviewed previous studies and summarized the essential elements of some successful resource-based cities, which are useful experiences for Chinese resource-based cities. Secondly, we studied the development of resource-based cities over the past 10 years with a focus on economic development, industrial structure, government revenue and environmental conditions. We found that resource-based cities were less developed compared to other cities. The main reasons are the after-effects of a planned economy, an unreasonable tax system, planning mistakes and misguided resources exploitation policies. Thirdly, we analyzed several aspects of the policy responses after the introduction of transition policies, including designating 69 resource-exhausted cities, supporting cities with funds and projects, formulating transition plans and evaluating transition performance. However, there are some deficiencies in the process of policy implementation. Finally, some recommendations were provided to improve transition performance and sustainable development for resource-based cities. - Highlights: ► Analyze the development of Chinese resource-based cities from four aspects. ► Analyze the causes of less development in resource-based cities. ► Investigate policies and their responses to transformation. ► Provide recommendations to improve transformation performance and sustainable development

Comparative Studies of High-Gradient Rf and Dc Breakdowns

CERN Document Server

Kovermann, Jan Wilhelm; Wuensch, Walter

2010-01-01

The CLIC project is based on normal-conducting high-gradient accelerating structures with an average accelerating gradient of 100 MV/m. The maximum achievable gradient in these structures is limited by the breakdown phenomenon. The physics of breakdowns is not yet fully understood quantitatively. A full knowledge could have strong impact on the design, material choice and construction of rf structures. Therefore, understanding breakdowns has great importance to reaching a gradient of 100MV/m with an acceptable breakdown probability. This thesis addresses the physics underlying the breakdown effect, focusing on a comparison of breakdowns in rf structures and in a dc spark setup. The dc system is simpler, easier to benchmark against simulations, with a faster turnaround time, but the relationship to rf breakdown must be established. To do so, an experimental approach based on optical diagnostics and electrical measurements methods was made. Following an introduction into the CLIC project, a general theoretical ...

A strain gradient plasticity theory with application to wire torsion

KAUST Repository

Liu, J. X.; El Sayed, Tamer S.

2014-01-01

Based on the framework of the existing strain gradient plasticity theories, we have examined three kinds of relations for the plastic strain dependence of the material intrinsic length scale, and thus developed updated strain gradient plasticity

Evidence-based medicine - an appropriate tool for evidence-based health policy? A case study from Norway.

Science.gov (United States)

Malterud, Kirsti; Bjelland, Anne Karen; Elvbakken, Kari Tove

2016-03-05

Evidence-based policy (EBP), a concept modelled on the principles of evidence-based medicine (EBM), is widely used in different areas of policymaking. Systematic reviews (SRs) with meta-analyses gradually became the methods of choice for synthesizing research evidence about interventions and judgements about quality of evidence and strength of recommendations. Critics have argued that the relation between research evidence and service policies is weak, and that the notion of EBP rests on a misunderstanding of policy processes. Having explored EBM standards and knowledge requirements for health policy decision-making, we present an empirical point of departure for discussing the relationship between EBM and EBP. In a case study exploring the Norwegian Knowledge Centre for the Health Services (NOKC), an independent government unit, we first searched for information about the background and development of the NOKC to establish a research context. We then identified, selected and organized official NOKC publications as an empirical sample of typical top-of-the-line knowledge delivery adhering to EBM standards. Finally, we explored conclusions in this type of publication, specifically addressing their potential as policy decision tools. From a total sample of 151 SRs published by the NOKC in the period 2004-2013, a purposive subsample from 2012 (14 publications) advised major caution about their conclusions because of the quality or relevance of the underlying documentation. Although the case study did not include a systematic investigation of uptake and policy consequences, SRs were found to be inappropriate as universal tools for health policy decision-making. The case study demonstrates that EBM is not necessarily suited to knowledge provision for every kind of policy decision-making. Our analysis raises the question of whether the evidence-based movement, represented here by an independent government organization, undertakes too broad a range of commissions using

Dexamethasone levels and base to apex concentration gradients in scala tympani perilymph following intracochlear delivery in the guinea pig

Science.gov (United States)

Hahn, Hartmut; Salt, Alec N.; Biegner, Thorsten; Kammerer, Bernd; Delabar, Ursular; Hartsock, Jared; Plontke, Stefan K.

2012-01-01

Hypothesis To determine whether intracochlearly applied dexamethasone will lead to better control of drug levels, higher peak concentrations and lower base-to apex concentration gradients in scala tympani (ST) of the guinea pig than after intratympanic (round window, RW) application. Background Local application of drugs to the RW results in substantial variation of intracochlear drug levels and significant base-to apex concentration gradients in ST. Methods Two μL of dexamethasone-phosphate (10 mg/mL) were injected into ST either through the RW membrane which was covered with 1% sodium hyaluronate gel or through a cochleostomy with a fluid tight seal of the micropipette. Perilymph was sequentially sampled from the apex at a single time point for each animal, at 20, 80, or 200 min after the injection ended. Results were mathematically interpreted by the means of an established computer model and compared with prior experiments performed by our group with the same experimental techniques but using intratympanic applications. Results Single intracochlear injections over 20 min resulted in approximately ten times higher peak concentrations (on average) than 2-3 hours of intratympanic application to the round window niche. Intracochlear drug levels were less variable and could be measured for at least up to 220 min. Concentration gradients along scala tympani were less pronounced. The remaining variability in intracochlear drug levels was attributable to perilymph and drug leak from the injection site. Conclusion With significantly higher, less variable drug levels and smaller base-to apex concentration gradients, intracochlear applications have advantages to intratympanic injections. For further development of this technique, it is of importance to control leaks of perilymph and drug from the injection site and to evaluate its clinical feasibility and associated risks. PMID:22588238

Lactate uptake against a concentration gradient

DEFF Research Database (Denmark)

Nordström, Carl-Henrik; Nielsen, Troels Halfeld; Nielsen, Hans Boye

2014-01-01

The recently published article by Jalloh et al (Jalloh I, Helmy A, Shannon RJ, Gallagher CN, Menon D, Carpenter K, Hutchinson P. Lactate uptake by the injured human brain - evidence from an arterio-venous gradient and cerebral microdialysis study. J Neurotrauma. 2013 Aug 22. [Epub ahead of print......]) concludes that lactate may be transported across the blood brain barrier into the brain against a concentration gradient. Unfortunately the authors have misinterpreted the concept of analytical imprecision and their conclusion is based on analytical artifact. As the topic of lactate transport into the brain...

Efficient L1 regularization-based reconstruction for fluorescent molecular tomography using restarted nonlinear conjugate gradient.

Science.gov (United States)

Shi, Junwei; Zhang, Bin; Liu, Fei; Luo, Jianwen; Bai, Jing

2013-09-15

For the ill-posed fluorescent molecular tomography (FMT) inverse problem, the L1 regularization can protect the high-frequency information like edges while effectively reduce the image noise. However, the state-of-the-art L1 regularization-based algorithms for FMT reconstruction are expensive in memory, especially for large-scale problems. An efficient L1 regularization-based reconstruction algorithm based on nonlinear conjugate gradient with restarted strategy is proposed to increase the computational speed with low memory consumption. The reconstruction results from phantom experiments demonstrate that the proposed algorithm can obtain high spatial resolution and high signal-to-noise ratio, as well as high localization accuracy for fluorescence targets.

Dai-Kou type conjugate gradient methods with a line search only using gradient.

Science.gov (United States)

Huang, Yuanyuan; Liu, Changhe

2017-01-01

In this paper, the Dai-Kou type conjugate gradient methods are developed to solve the optimality condition of an unconstrained optimization, they only utilize gradient information and have broader application scope. Under suitable conditions, the developed methods are globally convergent. Numerical tests and comparisons with the PRP+ conjugate gradient method only using gradient show that the methods are efficient.

Policy-based Network Management in Home Area Networks: Interim Test Results

OpenAIRE

Ibrahim Rana, Annie; Ó Foghlú, Mícheál

2009-01-01

This paper argues that Home Area Networks (HANs) are a good candidate for advanced network management automation techniques, such as Policy-Based Network Management (PBNM). What is proposed is a simple use of policy based network management to introduce some level of Quality of Service (QoS) and Security management in the HAN, whilst hiding this complexity from the home user. In this paper we have presented the interim test results of our research experiments (based on a scenario) using the H...

A Sea-Sky Line Detection Method for Unmanned Surface Vehicles Based on Gradient Saliency.

Science.gov (United States)

Wang, Bo; Su, Yumin; Wan, Lei

2016-04-15

Special features in real marine environments such as cloud clutter, sea glint and weather conditions always result in various kinds of interference in optical images, which make it very difficult for unmanned surface vehicles (USVs) to detect the sea-sky line (SSL) accurately. To solve this problem a saliency-based SSL detection method is proposed. Through the computation of gradient saliency the line features of SSL are enhanced effectively, while other interference factors are relatively suppressed, and line support regions are obtained by a region growing method on gradient orientation. The SSL identification is achieved according to region contrast, line segment length and orientation features, and optimal state estimation of SSL detection is implemented by introducing a cubature Kalman filter (CKF). In the end, the proposed method is tested on a benchmark dataset from the "XL" USV in a real marine environment, and the experimental results demonstrate that the proposed method is significantly superior to other state-of-the-art methods in terms of accuracy rate and real-time performance, and its accuracy and stability are effectively improved by the CKF.

MODIFIED ARMIJO RULE ON GRADIENT DESCENT AND CONJUGATE GRADIENT

Directory of Open Access Journals (Sweden)

ZURAIDAH FITRIAH

2017-10-01

Full Text Available Armijo rule is an inexact line search method to determine step size in some descent method to solve unconstrained local optimization. Modified Armijo was introduced to increase the numerical performance of several descent algorithms that applying this method. The basic difference of Armijo and its modified are in existence of a parameter and estimating the parameter that is updated in every iteration. This article is comparing numerical solution and time of computation of gradient descent and conjugate gradient hybrid Gilbert-Nocedal (CGHGN that applying modified Armijo rule. From program implementation in Matlab 6, it's known that gradient descent was applying modified Armijo more effectively than CGHGN from one side: iteration needed to reach some norm of the gradient  (input by the user. The amount of iteration was representing how long the step size of each algorithm in each iteration. In another side, time of computation has the same conclusion.

Formation of actin networks in microfluidic concentration gradients

Directory of Open Access Journals (Sweden)

Natalja eStrelnikova

2016-05-01

Full Text Available The physical properties of cytoskeletal networks are contributors in a number of mechanical responses of cells including cellular deformation and locomotion, and are crucial for the proper action of living cells. Local chemical gradients modulate cytoskeletal functionality including the interactions of the cytoskeleton with other cellular components. Actin is a major constituent of the cytoskeleton. Introducing a microfluidic-based platform, we explored the impact of concentration gradients on the formation and structural properties of actin networks. Microfluidics-controlled flow-free steady state experimental conditions allow for the generation of chemical gradients of different profiles, such as linear or step-like. We discovered specific features of actin networks emerging in defined gradients. In particular, we analyzed the effects of spatial conditions on network properties, bending rigidities of network links, and the network elasticity.

Dose gradient curve: A new tool for evaluating dose gradient.

Science.gov (United States)

Sung, KiHoon; Choi, Young Eun

2018-01-01

Stereotactic radiotherapy, which delivers an ablative high radiation dose to a target volume for maximum local tumor control, requires a rapid dose fall-off outside the target volume to prevent extensive damage to nearby normal tissue. Currently, there is no tool to comprehensively evaluate the dose gradient near the target volume. We propose the dose gradient curve (DGC) as a new tool to evaluate the quality of a treatment plan with respect to the dose fall-off characteristics. The average distance between two isodose surfaces was represented by the dose gradient index (DGI) estimated by a simple equation using the volume and surface area of isodose levels. The surface area was calculated by mesh generation and surface triangulation. The DGC was defined as a plot of the DGI of each dose interval as a function of the dose. Two types of DGCs, differential and cumulative, were generated. The performance of the DGC was evaluated using stereotactic radiosurgery plans for virtual targets. Over the range of dose distributions, the dose gradient of each dose interval was well-characterized by the DGC in an easily understandable graph format. Significant changes in the DGC were observed reflecting the differences in planning situations and various prescription doses. The DGC is a rational method for visualizing the dose gradient as the average distance between two isodose surfaces; the shorter the distance, the steeper the dose gradient. By combining the DGC with the dose-volume histogram (DVH) in a single plot, the DGC can be utilized to evaluate not only the dose gradient but also the target coverage in routine clinical practice.

Gradient algorithm applied to laboratory quantum control

International Nuclear Information System (INIS)

Roslund, Jonathan; Rabitz, Herschel

2009-01-01

The exploration of a quantum control landscape, which is the physical observable as a function of the control variables, is fundamental for understanding the ability to perform observable optimization in the laboratory. For high control variable dimensions, trajectory-based methods provide a means for performing such systematic explorations by exploiting the measured gradient of the observable with respect to the control variables. This paper presents a practical, robust, easily implemented statistical method for obtaining the gradient on a general quantum control landscape in the presence of noise. In order to demonstrate the method's utility, the experimentally measured gradient is utilized as input in steepest-ascent trajectories on the landscapes of three model quantum control problems: spectrally filtered and integrated second harmonic generation as well as excitation of atomic rubidium. The gradient algorithm achieves efficiency gains of up to approximately three times that of the standard genetic algorithm and, as such, is a promising tool for meeting quantum control optimization goals as well as landscape analyses. The landscape trajectories directed by the gradient should aid in the continued investigation and understanding of controlled quantum phenomena.

Analysis of magnetic gradients to study gravitropism.

Science.gov (United States)

Hasenstein, Karl H; John, Susan; Scherp, Peter; Povinelli, Daniel; Mopper, Susan

2013-01-01

Gravitropism typically is generated by dense particles that respond to gravity. Experimental stimulation by high-gradient magnetic fields provides a new approach to selectively manipulate the gravisensing system. The movement of corn, wheat, and potato starch grains in suspension was examined with videomicroscopy during parabolic flights that generated 20 to 25 s of weightlessness. During weightlessness, a magnetic gradient was generated by inserting a wedge into a uniform, external magnetic field that caused repulsion of starch grains. The resultant velocity of movement was compared with the velocity of sedimentation under 1 g conditions. The high-gradient magnetic fields repelled the starch grains and generated a force of at least 0.6 g. Different wedge shapes significantly affected starch velocity and directionality of movement. Magnetic gradients are able to move diamagnetic compounds under weightless or microgravity conditions and serve as directional stimulus during seed germination in low-gravity environments. Further work can determine whether gravity sensing is based on force or contact between amyloplasts and statocyte membrane system.

Gradient computation for VTI acoustic wavefield tomography

KAUST Repository

Li, Vladimir

2016-09-06

Wavefield tomography can handle complex subsurface geology better than ray-based techniques and, ultimately, provide a higher resolution. Here, we implement forward and adjoint wavefield extrapolation for VTI (transversely isotropic with a vertical symmetry axis) media using a pseudospectral operator that employes a separable approximation of the P-wave dispersion relation. This operator is employed to derive the gradients of the differential semblance optimization (DSO) and modified stack-power objective functions. We also obtain the gradient expressions for the data-domain objective function, which can incorporate borehole information necessary for stable VTI velocity analysis. These gradients are compared to the ones obtained with a space-time finite-difference (FD) scheme for a system of coupled wave equations. Whereas the kernels computed with the two wave-equation operators are similar, the pseudospectral method is not hampered by the imprint of the shear-wave artifact. Numerical examples also show that the modified stack-power objective function produces cleaner gradients than the more conventional DSO operator.

Democratic population decisions result in robust policy-gradient learning: a parametric study with GPU simulations.

Directory of Open Access Journals (Sweden)

Paul Richmond

2011-05-01

Full Text Available High performance computing on the Graphics Processing Unit (GPU is an emerging field driven by the promise of high computational power at a low cost. However, GPU programming is a non-trivial task and moreover architectural limitations raise the question of whether investing effort in this direction may be worthwhile. In this work, we use GPU programming to simulate a two-layer network of Integrate-and-Fire neurons with varying degrees of recurrent connectivity and investigate its ability to learn a simplified navigation task using a policy-gradient learning rule stemming from Reinforcement Learning. The purpose of this paper is twofold. First, we want to support the use of GPUs in the field of Computational Neuroscience. Second, using GPU computing power, we investigate the conditions under which the said architecture and learning rule demonstrate best performance. Our work indicates that networks featuring strong Mexican-Hat-shaped recurrent connections in the top layer, where decision making is governed by the formation of a stable activity bump in the neural population (a "non-democratic" mechanism, achieve mediocre learning results at best. In absence of recurrent connections, where all neurons "vote" independently ("democratic" for a decision via population vector readout, the task is generally learned better and more robustly. Our study would have been extremely difficult on a desktop computer without the use of GPU programming. We present the routines developed for this purpose and show that a speed improvement of 5x up to 42x is provided versus optimised Python code. The higher speed is achieved when we exploit the parallelism of the GPU in the search of learning parameters. This suggests that efficient GPU programming can significantly reduce the time needed for simulating networks of spiking neurons, particularly when multiple parameter configurations are investigated.

Three-dimensional Gravity Inversion with a New Gradient Scheme on Unstructured Grids

Science.gov (United States)

Sun, S.; Yin, C.; Gao, X.; Liu, Y.; Zhang, B.

2017-12-01

Stabilized gradient-based methods have been proved to be efficient for inverse problems. Based on these methods, setting gradient close to zero can effectively minimize the objective function. Thus the gradient of objective function determines the inversion results. By analyzing the cause of poor resolution on depth in gradient-based gravity inversion methods, we find that imposing depth weighting functional in conventional gradient can improve the depth resolution to some extent. However, the improvement is affected by the regularization parameter and the effect of the regularization term becomes smaller with increasing depth (shown as Figure 1 (a)). In this paper, we propose a new gradient scheme for gravity inversion by introducing a weighted model vector. The new gradient can improve the depth resolution more efficiently, which is independent of the regularization parameter, and the effect of regularization term will not be weakened when depth increases. Besides, fuzzy c-means clustering method and smooth operator are both used as regularization terms to yield an internal consecutive inverse model with sharp boundaries (Sun and Li, 2015). We have tested our new gradient scheme with unstructured grids on synthetic data to illustrate the effectiveness of the algorithm. Gravity forward modeling with unstructured grids is based on the algorithm proposed by Okbe (1979). We use a linear conjugate gradient inversion scheme to solve the inversion problem. The numerical experiments show a great improvement in depth resolution compared with regular gradient scheme, and the inverse model is compact at all depths (shown as Figure 1 (b)). AcknowledgeThis research is supported by Key Program of National Natural Science Foundation of China (41530320), China Natural Science Foundation for Young Scientists (41404093), and Key National Research Project of China (2016YFC0303100, 2017YFC0601900). ReferencesSun J, Li Y. 2015. Multidomain petrophysically constrained inversion and

Development of a New Gradient Based Strain-Criterion for Prediction of Bendability in Quality Assurance and FEA

Science.gov (United States)

Denninger, Ralf; Liewald, Mathias; Sindel, Manfred

2011-08-01

Numerical simulation systems are more and more used in process development of car bodies. Nowadays, also the hemming process is optimised in FEA. Thus, the analysing of process robustness calls for a failure criterion for the specific bending and hemming load condition. For that purpose the experimental determination of bendability under various pre-load conditions that occur in real production, e.g. during deep drawing in press shop, is content of this contribution. Using these experimental results, a new approach for a strain-gradient based failure criterion for bending operations is presented to optimise bendability prediction. The bending-strain-gradient approach can be used both in production related departments of quality assurance as well as for simulative process design or process validation for vehicle manufacturing planning.

Dexamethasone levels and base-to-apex concentration gradients in the scala tympani perilymph after intracochlear delivery in the guinea pig.

Science.gov (United States)

Hahn, Hartmut; Salt, Alec N; Biegner, Thorsten; Kammerer, Bernd; Delabar, Ursular; Hartsock, Jared J; Plontke, Stefan K

2012-06-01

To determine whether intracochlearly applied dexamethasone will lead to better control of drug levels, higher peak concentrations, and lower base-to-apex concentration gradients in the scala tympani (ST) of the guinea pig than after intratympanic (round window [RW]) application. Local application of drugs to the RW results in substantial variation of intracochlear drug levels and significant base-to-apex concentration gradients in ST. Two microliters of dexamethasone-phosphate (10 mg/ml) were injected into ST either through the RW membrane, which was covered with 1% sodium hyaluronate gel or through a cochleostomy with a fluid tight seal of the micropipette. Perilymph was sequentially sampled from the apex at a single time point for each animal, at 20, 80, or 200 min after the injection ended. Results were mathematically interpreted by means of an established computer model and compared with previous experiments performed by our group with the same experimental techniques but using intratympanic applications. Single intracochlear injections of 20 minutes resulted in approximately 10 times higher peak concentrations (on average) than 2 to 3 hours of intratympanic application to the RW niche. Intracochlear drug levels were less variable and could be measured for over 220 minutes. Concentration gradients along the scala tympani were less pronounced. The remaining variability in intracochlear drug levels was attributable to perilymph and drug leak from the injection site. With significantly higher, less variable drug levels and smaller base-to-apex concentration gradients, intracochlear applications have advantages to intratympanic injections. For further development of this technique, it is of importance to control leaks of perilymph and drug from the injection site and to evaluate its clinical feasibility and associated risks.

Estimating Soil Hydraulic Parameters using Gradient Based Approach

Science.gov (United States)

Rai, P. K.; Tripathi, S.

2017-12-01

The conventional way of estimating parameters of a differential equation is to minimize the error between the observations and their estimates. The estimates are produced from forward solution (numerical or analytical) of differential equation assuming a set of parameters. Parameter estimation using the conventional approach requires high computational cost, setting-up of initial and boundary conditions, and formation of difference equations in case the forward solution is obtained numerically. Gaussian process based approaches like Gaussian Process Ordinary Differential Equation (GPODE) and Adaptive Gradient Matching (AGM) have been developed to estimate the parameters of Ordinary Differential Equations without explicitly solving them. Claims have been made that these approaches can straightforwardly be extended to Partial Differential Equations; however, it has been never demonstrated. This study extends AGM approach to PDEs and applies it for estimating parameters of Richards equation. Unlike the conventional approach, the AGM approach does not require setting-up of initial and boundary conditions explicitly, which is often difficult in real world application of Richards equation. The developed methodology was applied to synthetic soil moisture data. It was seen that the proposed methodology can estimate the soil hydraulic parameters correctly and can be a potential alternative to the conventional method.

Human impact gradient on mammalian biodiversity

Directory of Open Access Journals (Sweden)

Mariana Munguía

2016-04-01

Full Text Available Drastic changes have been caused by human influence in natural landscapes, which may exert an intensive effect on species loss. However, species loss from human pressure is not random but depends on a series of environmentally associated factors. Linking species traits to environmental attributes may allow us to detect the ecological impacts of habitat so that meaningful habitat degradation gradients can be identified. The relationships between environmental factors and species traits provide the basis for identifying those biological traits that make species more sensitive to disturbance. These relationships are also helpful to detect the geographic distribution of latent risk to reveal areas where biodiversity is threatened. Here, we identify a “Human Impact Gradient for Biodiversity (HIGB” based on a three-table ordination method (RLQ analysis and fourth-corner analysis to identify key species traits that are associated with environmental gradient. Species distribution and environmental geographic data were gathered nationwide to analyze 68 localities, which represent 27% of Mexico’s surface, including 211 species of mammals. Nine environmental variables (including biophysical, geophysical and land-use impacts were analyzed by using the Geographic Information System. Three types of species’ traits were evaluated: locomotion, trophic habit and body size. We identified a human impact gradient, which was mainly determined by the percentage of the area that was covered by seedlings, the plant richness, the understory coverage percentage and the human settlement index. The most important species traits that are associated with non-human-impacted sites were carnivores, frugivores–herbivores and a body size that was greater than 17.8 kg; 25 species were selected by the decision criteria framework for species that were sensitive to degradation based on ecological function information. Conversely, granivores, fossorial and semifossorial

Gradient pre-emphasis to counteract first-order concomitant fields on asymmetric MRI gradient systems.

Science.gov (United States)

Tao, Shengzhen; Weavers, Paul T; Trzasko, Joshua D; Shu, Yunhong; Huston, John; Lee, Seung-Kyun; Frigo, Louis M; Bernstein, Matt A

2017-06-01

To develop a gradient pre-emphasis scheme that prospectively counteracts the effects of the first-order concomitant fields for any arbitrary gradient waveform played on asymmetric gradient systems, and to demonstrate the effectiveness of this approach using a real-time implementation on a compact gradient system. After reviewing the first-order concomitant fields that are present on asymmetric gradients, we developed a generalized gradient pre-emphasis model assuming arbitrary gradient waveforms to counteract their effects. A numerically straightforward, easily implemented approximate solution to this pre-emphasis problem was derived that was compatible with the current hardware infrastructure of conventional MRI scanners for eddy current compensation. The proposed method was implemented on the gradient driver subsystem, and its real-time use was tested using a series of phantom and in vivo data acquired from two-dimensional Cartesian phase-difference, echo-planar imaging, and spiral acquisitions. The phantom and in vivo results demonstrated that unless accounted for, first-order concomitant fields introduce considerable phase estimation error into the measured data and result in images with spatially dependent blurring/distortion. The resulting artifacts were effectively prevented using the proposed gradient pre-emphasis. We have developed an efficient and effective gradient pre-emphasis framework to counteract the effects of first-order concomitant fields of asymmetric gradient systems. Magn Reson Med 77:2250-2262, 2017. © 2016 International Society for Magnetic Resonance in Medicine. © 2016 International Society for Magnetic Resonance in Medicine.

ℓ0 Gradient Minimization Based Image Reconstruction for Limited-Angle Computed Tomography.

Directory of Open Access Journals (Sweden)

Wei Yu

Full Text Available In medical and industrial applications of computed tomography (CT imaging, limited by the scanning environment and the risk of excessive X-ray radiation exposure imposed to the patients, reconstructing high quality CT images from limited projection data has become a hot topic. X-ray imaging in limited scanning angular range is an effective imaging modality to reduce the radiation dose to the patients. As the projection data available in this modality are incomplete, limited-angle CT image reconstruction is actually an ill-posed inverse problem. To solve the problem, image reconstructed by conventional filtered back projection (FBP algorithm frequently results in conspicuous streak artifacts and gradual changed artifacts nearby edges. Image reconstruction based on total variation minimization (TVM can significantly reduce streak artifacts in few-view CT, but it suffers from the gradual changed artifacts nearby edges in limited-angle CT. To suppress this kind of artifacts, we develop an image reconstruction algorithm based on ℓ0 gradient minimization for limited-angle CT in this paper. The ℓ0-norm of the image gradient is taken as the regularization function in the framework of developed reconstruction model. We transformed the optimization problem into a few optimization sub-problems and then, solved these sub-problems in the manner of alternating iteration. Numerical experiments are performed to validate the efficiency and the feasibility of the developed algorithm. From the statistical analysis results of the performance evaluations peak signal-to-noise ratio (PSNR and normalized root mean square distance (NRMSD, it shows that there are significant statistical differences between different algorithms from different scanning angular ranges (p<0.0001. From the experimental results, it also indicates that the developed algorithm outperforms classical reconstruction algorithms in suppressing the streak artifacts and the gradual changed

To What Extent Are Canadian Second Language Policies Evidence-Based? Reflections on the Intersections of Research and Policy

Directory of Open Access Journals (Sweden)

Jim eCummins

2014-05-01

Full Text Available The paper addresses the intersections between research, ideology, and Canadian educational policies focusing on four major areas: (a core and immersion programs for the teaching of French to Anglophone students, (b policies concerning the learning of English and French by students from immigrant backgrounds, (c heritage language teaching, and (d the education of Deaf and hard-of hearing students. With respect to the teaching of French, policy-makers have largely ignored the fact that most core French programs produce meager results for the vast majority of students. Only a small proportion of students (< 10% attend more effective alternatives (e.g. French immersion and Intensive French programs. With respect to immigrant-background students, a large majority of teachers and administrators have not had opportunities to access the knowledge base regarding effective instruction for these students nor have they had opportunities for pre-service or in-service professional development regarding effective instructional practices. Educational policies have also treated the linguistic resources that children bring to school with, at best, benign neglect. In some cases (e.g., Ontario school systems have been explicitly prohibited from instituting enrichment bilingual programs that would promote students’ bilingualism and biliteracy. Finally, with respect to Deaf students, policy-makers have ignored overwhelming research on the positive relationship between academic success and the development of proficiency in natural sign languages, preferring instead to perpetuate the falsehood that acquisition of languages such as American Sign Language by young children (with or without cochlear implants will impede children’s language and academic development. The paper reviews the kinds of policies, programs, and practices that could be implemented (at no additional cost if policy-makers and educators pursued evidence-based educational policies.

To what extent are Canadian second language policies evidence-based? Reflections on the intersections of research and policy.

Science.gov (United States)

Cummins, Jim

2014-01-01

THE PAPER ADDRESSES THE INTERSECTIONS BETWEEN RESEARCH FINDINGS AND CANADIAN EDUCATIONAL POLICIES FOCUSING ON FOUR MAJOR AREAS: (a) core and immersion programs for the teaching of French to Anglophone students, (b) policies concerning the learning of English and French by students from immigrant backgrounds, (c) heritage language teaching, and (d) the education of Deaf and hard-of hearing students. With respect to the teaching of French, policy-makers have largely ignored the fact that most core French programs produce meager results for the vast majority of students. Only a small proportion of students (languages, preferring instead to leave uncorrected the proposition that acquisition of languages such as American Sign Language by young children (with or without cochlear implants) will impede children's language and academic development. The paper reviews the kinds of policies, programs, and practices that could be implemented (at no additional cost) if policy-makers and educators pursued evidence-based educational policies.

A condition-based maintenance policy for stochastically deteriorating systems

International Nuclear Information System (INIS)

Grall, A.; Berenguer, C.; Dieulle, L.

2002-01-01

We focus on the analytical modeling of a condition-based inspection/replacement policy for a stochastically and continuously deteriorating single-unit system. We consider both the replacement threshold and the inspection schedule as decision variables for this maintenance problem and we propose to implement the maintenance policy using a multi-level control-limit rule. In order to assess the performance of the proposed maintenance policy and to minimize the long run expected maintenance cost per unit time, a mathematical model for the maintained system cost is derived, supported by the existence of a stationary law for the maintained system state. Numerical experiments illustrate the performance of the proposed policy and confirm that the maintenance cost rate on an infinite horizon can be minimized by a joint optimization of the maintenance structure thresholds, or equivalently by a joint optimization of a system replacement threshold and the aperiodic inspection schedule

Research-Based Knowledge: Researchers' Contribution to Evidence-Based Practice and Policy Making in Career Guidance

Science.gov (United States)

Haug, Erik Hagaseth; Plant, Peter

2016-01-01

To present evidence for the outcomes of career guidance is increasingly seen as pivotal for a further professionalization of policy making and service provision. This paper puts an emphasis on researchers' contribution to evidence-based practice and policy making in career guidance. We argue for a broader and more pluralistic research strategy to…

Fire Regime Characteristics along Environmental Gradients in Spain

Directory of Open Access Journals (Sweden)

María Vanesa Moreno

2016-11-01

Full Text Available Concern regarding global change has increased the need to understand the relationship between fire regime characteristics and the environment. Pyrogeographical theory suggests that fire regimes are constrained by climate, vegetation and fire ignition processes, but it is not obvious how fire regime characteristics are related to those factors. We used a three-matrix approach with a multivariate statistical methodology that combined an ordination method and fourth-corner analysis for hypothesis testing to investigate the relationship between fire regime characteristics and environmental gradients across Spain. Our results suggest that fire regime characteristics (i.e., density and seasonality of fire activity are constrained primarily by direct gradients based on climate, population, and resource gradients based on forest potential productivity. Our results can be used to establish a predictive model for how fire regimes emerge in order to support fire management, particularly as global environmental changes impact fire regime characteristics.

Fabrication of Ni-Al/diamond composite based on layered and gradient structures of SHS system

Directory of Open Access Journals (Sweden)

Lu Jiafeng

2017-01-01

Full Text Available In this paper layered and gradient structures of Ni-Al SHS system were adopted to manufacture Ni-Al/diamond composites. The effect of the layered and the diamond mesh gradient structures of Ni-Al/diamond on the SHS process and the microstructure of the composites were investigated. It is found that with the increasing of the number of layers, the combustion wave velocity is decreased. The combustion wave velocity for diamond mesh size gradient structure of Ni-Al SHS is faster than that for the layered structure. A well bonding can be formed between diamond and the matrix in layered and gradient structure Ni-Al/diamond composites due to the melt of Ni-Cr brazing alloy.

Validation of measured poleward TEC gradient using multi-station GPS with Artificial Neural Network based TEC model in low latitude region for developing predictive capability of ionospheric scintillation

Science.gov (United States)

Sur, D.; Paul, A.

2017-12-01

The equatorial ionosphere shows sharp diurnal and latitudinal Total Electron Content (TEC) variations over a major part of the day. Equatorial ionosphere also exhibits intense post-sunset ionospheric irregularities. Accurate prediction of TEC in these low latitudes is not possible from standard ionospheric models. An Artificial Neural Network (ANN) based Vertical TEC (VTEC) model has been designed using TEC data in low latitude Indian longitude sector for accurate prediction of VTEC. GPS TEC data from the stations Calcutta (22.58°N, 88.38°E geographic, magnetic dip 32°), Baharampore (24.09°N, 88.25°E geographic, magnetic dip 35°) and Siliguri (26.72°N, 88.39°E geographic; magnetic dip 40°) are used as training dataset for the duration of January 2007-September 2011. Poleward VTEC gradients from northern EIA crest to region beyond EIA crest have been calculated from measured VTEC and compared with that obtained from ANN based VTEC model. TEC data from Calcutta and Siliguri are used to compute VTEC gradients during April 2013 and August-September 2013. It has been observed that poleward VTEC gradient computed from ANN based TEC model has shown good correlation with measured values during vernal and autumnal equinoxes of high solar activity periods of 2013. Possible correlation between measured poleward TEC gradients and post-sunset scintillations (S4 ≥ 0.4) from northern crest of EIA has been observed in this paper. From the observation, a suitable threshold poleward VTEC gradient has been proposed for possible occurrence of post-sunset scintillations at northern crest of EIA along 88°E longitude. Poleward VTEC gradients obtained from ANN based VTEC model are used to forecast possible ionospheric scintillation after post-sunset period using the threshold value. It has been observed that these predicted VTEC gradients obtained from ANN based VTEC model can forecast post-sunset L-band scintillation with an accuracy of 67% to 82% in this dynamic low latitude

A Critical Assessment of Evidence-Based Policy and Practice in Social Work.

Science.gov (United States)

Diaz, Clive; Drewery, Sian

2016-01-01

In this article the authors consider how effective social work has been in terms of evidence-based policies and practice. They consider the role that "evidence" plays in policy making both in the wider context and, in particular, in relation to social work. The authors argue that there are numerous voices in the policy-making process and evidence only plays a minor role in terms of policy development and practice in social work.

Optimal random perturbations for stochastic approximation using a simultaneous perturbation gradient approximation

DEFF Research Database (Denmark)

Sadegh, Payman; Spall, J. C.

1998-01-01

simultaneous perturbation approximation to the gradient based on loss function measurements. SPSA is based on picking a simultaneous perturbation (random) vector in a Monte Carlo fashion as part of generating the approximation to the gradient. This paper derives the optimal distribution for the Monte Carlo...

Two dimensional dynamic analysis of sandwich plates with gradient foam cores

Energy Technology Data Exchange (ETDEWEB)

Mu, Lin; Xiao, Deng Bao; Zhao, Guiping [State Key Laboratory for Mechanical structure Strength and Vibration, School of AerospaceXi' an Jiaotong University, Xi' an (China); Cho, Chong Du [Dept. of Mechanical Engineering, Inha University, Inchon (Korea, Republic of)

2016-09-15

Present investigation is concerned about dynamic response of composite sandwich plates with the functionally gradient foam cores under time-dependent impulse. The analysis is based on a model of the gradient sandwich plate, in which the face sheets and the core adopt the Kirchhoff theory and a [2, 1]-order theory, respectively. The material properties of the gradient foam core vary continuously along the thickness direction. The gradient plate model is validated with the finite element code ABAQUS®. And the results show that the proposed model can predict well the free vibration of composite sandwich plates with gradient foam cores. The influences of gradient foam cores on the natural frequency, deflection and energy absorbing of the sandwich plates are also investigated.

Exploration Opportunity Search of Near-earth Objects Based on Analytical Gradients

Science.gov (United States)

Ren, Yuan; Cui, Ping-Yuan; Luan, En-Jie

2008-07-01

The problem of search of opportunity for the exploration of near-earth minor objects is investigated. For rendezvous missions, the analytical gradients of the performance index with respect to the free parameters are derived using the variational calculus and the theory of state-transition matrix. After generating randomly some initial guesses in the search space, the performance index is optimized, guided by the analytical gradients, leading to the local minimum points representing the potential launch opportunities. This method not only keeps the global-search property of the traditional method, but also avoids the blindness in the latter, thereby increasing greatly the computing speed. Furthermore, with this method, the searching precision could be controlled effectively.

Rationality versus reality: the challenges of evidence-based decision making for health policy makers.

Science.gov (United States)

McCaughey, Deirdre; Bruning, Nealia S

2010-05-26

Current healthcare systems have extended the evidence-based medicine (EBM) approach to health policy and delivery decisions, such as access-to-care, healthcare funding and health program continuance, through attempts to integrate valid and reliable evidence into the decision making process. These policy decisions have major impacts on society and have high personal and financial costs associated with those decisions. Decision models such as these function under a shared assumption of rational choice and utility maximization in the decision-making process. We contend that health policy decision makers are generally unable to attain the basic goals of evidence-based decision making (EBDM) and evidence-based policy making (EBPM) because humans make decisions with their naturally limited, faulty, and biased decision-making processes. A cognitive information processing framework is presented to support this argument, and subtle cognitive processing mechanisms are introduced to support the focal thesis: health policy makers' decisions are influenced by the subjective manner in which they individually process decision-relevant information rather than on the objective merits of the evidence alone. As such, subsequent health policy decisions do not necessarily achieve the goals of evidence-based policy making, such as maximizing health outcomes for society based on valid and reliable research evidence. In this era of increasing adoption of evidence-based healthcare models, the rational choice, utility maximizing assumptions in EBDM and EBPM, must be critically evaluated to ensure effective and high-quality health policy decisions. The cognitive information processing framework presented here will aid health policy decision makers by identifying how their decisions might be subtly influenced by non-rational factors. In this paper, we identify some of the biases and potential intervention points and provide some initial suggestions about how the EBDM/EBPM process can be

Rationality versus reality: the challenges of evidence-based decision making for health policy makers

Directory of Open Access Journals (Sweden)

Bruning Nealia S

2010-05-01

Full Text Available Abstract Background Current healthcare systems have extended the evidence-based medicine (EBM approach to health policy and delivery decisions, such as access-to-care, healthcare funding and health program continuance, through attempts to integrate valid and reliable evidence into the decision making process. These policy decisions have major impacts on society and have high personal and financial costs associated with those decisions. Decision models such as these function under a shared assumption of rational choice and utility maximization in the decision-making process. Discussion We contend that health policy decision makers are generally unable to attain the basic goals of evidence-based decision making (EBDM and evidence-based policy making (EBPM because humans make decisions with their naturally limited, faulty, and biased decision-making processes. A cognitive information processing framework is presented to support this argument, and subtle cognitive processing mechanisms are introduced to support the focal thesis: health policy makers' decisions are influenced by the subjective manner in which they individually process decision-relevant information rather than on the objective merits of the evidence alone. As such, subsequent health policy decisions do not necessarily achieve the goals of evidence-based policy making, such as maximizing health outcomes for society based on valid and reliable research evidence. Summary In this era of increasing adoption of evidence-based healthcare models, the rational choice, utility maximizing assumptions in EBDM and EBPM, must be critically evaluated to ensure effective and high-quality health policy decisions. The cognitive information processing framework presented here will aid health policy decision makers by identifying how their decisions might be subtly influenced by non-rational factors. In this paper, we identify some of the biases and potential intervention points and provide some initial

Rationality versus reality: the challenges of evidence-based decision making for health policy makers

Science.gov (United States)

2010-01-01

Background Current healthcare systems have extended the evidence-based medicine (EBM) approach to health policy and delivery decisions, such as access-to-care, healthcare funding and health program continuance, through attempts to integrate valid and reliable evidence into the decision making process. These policy decisions have major impacts on society and have high personal and financial costs associated with those decisions. Decision models such as these function under a shared assumption of rational choice and utility maximization in the decision-making process. Discussion We contend that health policy decision makers are generally unable to attain the basic goals of evidence-based decision making (EBDM) and evidence-based policy making (EBPM) because humans make decisions with their naturally limited, faulty, and biased decision-making processes. A cognitive information processing framework is presented to support this argument, and subtle cognitive processing mechanisms are introduced to support the focal thesis: health policy makers' decisions are influenced by the subjective manner in which they individually process decision-relevant information rather than on the objective merits of the evidence alone. As such, subsequent health policy decisions do not necessarily achieve the goals of evidence-based policy making, such as maximizing health outcomes for society based on valid and reliable research evidence. Summary In this era of increasing adoption of evidence-based healthcare models, the rational choice, utility maximizing assumptions in EBDM and EBPM, must be critically evaluated to ensure effective and high-quality health policy decisions. The cognitive information processing framework presented here will aid health policy decision makers by identifying how their decisions might be subtly influenced by non-rational factors. In this paper, we identify some of the biases and potential intervention points and provide some initial suggestions about how the

The theory-based policy evaluation method applied to the ex-post evaluation of climate change policies in the built environment in the Netherlands

International Nuclear Information System (INIS)

Harmelink, Mirjam; Joosen, Suzanne; Blok, Kornelis

2005-01-01

The challenge within ex-post policy evaluation research is to unravel the whole policy process and evaluate the effect and effectiveness of the different steps. Through this unravelling of the policy implementation process, insight is gained on where something went wrong in the process of policy design and implementation and where the keys are for improving the effectiveness and efficiency. This article presents the results of an ex-post policy evaluation of the effect and effectiveness of the Energy Premium Regulation scheme and the Long Term Voluntary agreements to reduce CO 2 emissions in the built environment in the Netherlands applying the theory-based policy evaluation method. The article starts with a description of the theory-based policy evaluation method. The method begins with the formulation of a program theory, which describes the 'ideal' operation of a policy instrument, from the viewpoint of the policy makers. Thereupon the theory is checked and adapted through interviews with policy makers and executors, and the cause and effect chain is finally translated to (quantitative) indicators. The article shows that the theory-based evaluation method has benefits over other ex-post evaluation methods that include: The whole policy implementation process is evaluated and the focus is not just on the 'end-result' (i.e. efficiency improvement and CO 2 emission reduction). Through the development of indicators for each step in the implementation process, 'successes and failures' are quantified to the greatest possible extent. By applying this approach we not only learn whether policies are successful or not, but also why they succeeded or failed and how they can be improved

Gradient-Based Optimization of Wind Farms with Different Turbine Heights

Energy Technology Data Exchange (ETDEWEB)

Stanley, Andrew P. J.; Thomas, Jared; Ning, Andrew; Annoni, Jennifer; Dykes, Katherine; Fleming, Paul

2017-01-09

Turbine wakes reduce power production in a wind farm. Current wind farms are generally built with turbines that are all the same height, but if wind farms included turbines with different tower heights, the cost of energy (COE) may be reduced. We used gradient-based optimization to demonstrate a method to optimize wind farms with varied hub heights. Our study includes a modified version of the FLORIS wake model that accommodates three-dimensional wakes integrated with a tower structural model. Our purpose was to design a process to minimize the COE of a wind farm through layout optimization and varying turbine hub heights. Results indicate that when a farm is optimized for layout and height with two separate height groups, COE can be lowered by as much as 5%-9%, compared to a similar layout and height optimization where all the towers are the same. The COE has the best improvement in farms with high turbine density and a low wind shear exponent.

Data-Based Decision Making at the Policy, Research, and Practice Levels

NARCIS (Netherlands)

Schildkamp, Kim; Ebbeler, J.

2015-01-01

Data-based decision making (DBDM) can lead to school improvement. However, schools struggle with the implementation of DBDM. In this symposium, we will discuss research and the implementation of DBDM at the national and regional policy level and the classroom level. We will discuss policy issues

Case-Based Policy and Goal Recognition

Science.gov (United States)

2015-09-30

Policy and Goal Recognizer (PaGR), a case- based system for multiagent keyhole recognition. PaGR is a knowledge recognition component within a decision...However, unlike our agent in the BVR domain, these recognition agents have access to perfect information. Single-agent keyhole plan recognition can be...listed below: 1. Facing Target 2. Closing on Target 3. Target Range 4. Within a Target’s Weapon Range 5. Has Target within Weapon Range 6. Is in Danger

Generation of tunable and pulsatile concentration gradients via microfluidic network

KAUST Repository

Zhou, Bingpu

2014-06-04

We demonstrate a compact Polydimethylsiloxane microfluidic chip which can quickly generate ten different chemical concentrations simultaneously. The concentration magnitude of each branch can be flexibly regulated based on the flow rate ratios of the two injecting streams. The temporal/pulsatile concentration gradients are achieved by integrating on-chip pneumatic actuated valves controlled by the external signals. The temporal concentration gradients can also be tuned precisely by varying applied frequency and duty cycle of the trigger signal. It is believed that such microdevice will be potentially used for some application areas of producing stable chemical gradients as well as allowing fast, pulsatile gradient transformation in seconds.

Informing principal policy reforms in South Africa through data-based evidence

Directory of Open Access Journals (Sweden)

Gabrielle Wills

2015-12-01

Full Text Available In the past decade there has been a notable shift in South African education policy that raises the value of school leadership as a lever for learning improvements. Despite a growing discourse on school leadership, there has been a lack of empirical based evidence on principals to inform, validate or debate the efficacy of proposed policies in raising the calibre of school principals. Drawing on findings from a larger study to understand the labour market for school principals in South Africa, this paper highlights four overarching characteristics of this market with implications for informing principal policy reforms. The paper notes that improving the design and implementation of policies guiding the appointment process for principals is a matter of urgency. A substantial and increasing number of principal replacements are taking place across South African schools given a rising age profile of school principals. In a context of low levels of principal mobility and high tenure, the leadership trajectory of the average school is established for nearly a decade with each principal replacement. Evidence-based policy making has a strong role to play in getting this right.

Joining of Tungsten Armor Using Functional Gradients

International Nuclear Information System (INIS)

John Scott O'Dell

2006-01-01

The joining of low thermal expansion armor materials such as tungsten to high thermal expansion heat sink materials has been a major problem in plasma facing component (PFC) development. Conventional planar bonding techniques have been unable to withstand the high thermal induced stresses resulting from fabrication and high heat flux testing. During this investigation, innovative functional gradient joints produced using vacuum plasma spray forming techniques have been developed for joining tungsten armor to copper alloy heat sinks. A model was developed to select the optimum gradient architecture. Based on the modeling effort, a 2mm copper rich gradient was selected. Vacuum plasma pray parameters and procedures were then developed to produce the functional gradient joint. Using these techniques, dual cooling channel, medium scale mockups (32mm wide x 400mm length) were produced with vacuum plasma spray formed tungsten armor. The thickness of the tungsten armor was up to 5mm thick. No evidence of debonding at the interface between the heat sink and the vacuum plasma sprayed material was observed.

Improved plenum pressure gradient facemaps for PKL reactors

International Nuclear Information System (INIS)

Crowley, D.A.; Hamm, L.L.

1988-05-01

This report documents the development of improved plenum pressure gradient facemaps* for PKL Mark 16--31 and Mark 22 reactor charges. These new maps are based on the 1985 L-area AC flow tests. Use of the L-area data base for estimating C-area plenum pressure gradient maps is inappropriate because the nozzle geometry plays a major role in determining the shape of the plenum pressure profile. These plenum pressure gradient facemaps are used in the emergency cooling system (ECS) and in the flow instability (FI) loss of coolant accident (LOCA) limits calculations. For the ECS LOCA limits calculations, the maps are used as input to the FLOWZONE computer code to determine the average flow within a flowzone during normal operating conditions. For the FI LOCA limits calculations, the maps are used as plenum pressure boundary conditions in the FLOWTRAN computer code to determine the maximum pre-incident assembly flow within a flowzone. These maps will also be used for flowzoning and transient protection limits analyses

Wetting of flat gradient surfaces.

Science.gov (United States)

Bormashenko, Edward

2018-04-01

Gradient, chemically modified, flat surfaces enable directed transport of droplets. Calculation of apparent contact angles inherent for gradient surfaces is challenging even for atomically flat ones. Wetting of gradient, flat solid surfaces is treated within the variational approach, under which the contact line is free to move along the substrate. Transversality conditions of the variational problem give rise to the generalized Young equation valid for gradient solid surfaces. The apparent (equilibrium) contact angle of a droplet, placed on a gradient surface depends on the radius of the contact line and the values of derivatives of interfacial tensions. The linear approximation of the problem is considered. It is demonstrated that the contact angle hysteresis is inevitable on gradient surfaces. Electrowetting of gradient surfaces is discussed. Copyright © 2018 Elsevier Inc. All rights reserved.

A Sea-Sky Line Detection Method for Unmanned Surface Vehicles Based on Gradient Saliency

Directory of Open Access Journals (Sweden)

Bo Wang

2016-04-01

Full Text Available Special features in real marine environments such as cloud clutter, sea glint and weather conditions always result in various kinds of interference in optical images, which make it very difficult for unmanned surface vehicles (USVs to detect the sea-sky line (SSL accurately. To solve this problem a saliency-based SSL detection method is proposed. Through the computation of gradient saliency the line features of SSL are enhanced effectively, while other interference factors are relatively suppressed, and line support regions are obtained by a region growing method on gradient orientation. The SSL identification is achieved according to region contrast, line segment length and orientation features, and optimal state estimation of SSL detection is implemented by introducing a cubature Kalman filter (CKF. In the end, the proposed method is tested on a benchmark dataset from the “XL” USV in a real marine environment, and the experimental results demonstrate that the proposed method is significantly superior to other state-of-the-art methods in terms of accuracy rate and real-time performance, and its accuracy and stability are effectively improved by the CKF.

Proper orthogonal decomposition-based estimations of the flow field from particle image velocimetry wall-gradient measurements in the backward-facing step flow

International Nuclear Information System (INIS)

Nguyen, Thien Duy; Wells, John Craig; Mokhasi, Paritosh; Rempfer, Dietmar

2010-01-01

In this paper, particle image velocimetry (PIV) results from the recirculation zone of a backward-facing step flow, of which the Reynolds number is 2800 based on bulk velocity upstream of the step and step height (h = 16.5 mm), are used to demonstrate the capability of proper orthogonal decomposition (POD)-based measurement models. Three-component PIV velocity fields are decomposed by POD into a set of spatial basis functions and a set of temporal coefficients. The measurement models are built to relate the low-order POD coefficients, determined from an ensemble of 1050 PIV fields by the 'snapshot' method, to the time-resolved wall gradients, measured by a near-wall measurement technique called stereo interfacial PIV. These models are evaluated in terms of reconstruction and prediction of the low-order temporal POD coefficients of the velocity fields. In order to determine the estimation coefficients of the measurement models, linear stochastic estimation (LSE), quadratic stochastic estimation (QSE), principal component regression (PCR) and kernel ridge regression (KRR) are applied. We denote such approaches as LSE-POD, QSE-POD, PCR-POD and KRR-POD. In addition to comparing the accuracy of measurement models, we introduce multi-time POD-based estimations in which past and future information of the wall-gradient events is used separately or combined. The results show that the multi-time estimation approaches can improve the prediction process. Among these approaches, the proposed multi-time KRR-POD estimation with an optimized window of past wall-gradient information yields the best prediction. Such a multi-time KRR-POD approach offers a useful tool for real-time flow estimation of the velocity field based on wall-gradient data

Gradient Dynamics and Entropy Production Maximization

Science.gov (United States)

Janečka, Adam; Pavelka, Michal

2018-01-01

We compare two methods for modeling dissipative processes, namely gradient dynamics and entropy production maximization. Both methods require similar physical inputs-how energy (or entropy) is stored and how it is dissipated. Gradient dynamics describes irreversible evolution by means of dissipation potential and entropy, it automatically satisfies Onsager reciprocal relations as well as their nonlinear generalization (Maxwell-Onsager relations), and it has statistical interpretation. Entropy production maximization is based on knowledge of free energy (or another thermodynamic potential) and entropy production. It also leads to the linear Onsager reciprocal relations and it has proven successful in thermodynamics of complex materials. Both methods are thermodynamically sound as they ensure approach to equilibrium, and we compare them and discuss their advantages and shortcomings. In particular, conditions under which the two approaches coincide and are capable of providing the same constitutive relations are identified. Besides, a commonly used but not often mentioned step in the entropy production maximization is pinpointed and the condition of incompressibility is incorporated into gradient dynamics.

A flexible environmental reuse/recycle policy based on economic strength.

Science.gov (United States)

Tsiliyannis, C A

2007-01-01

Environmental policies based on fixed recycling rates may lead to increased environmental impacts (e.g., landfilled wastes) during economic expansion. A rate policy is proposed, which is adjusted according to the overall strength or weakness of the economy, as reflected by overall packaging demand and consumption, production and imports-exports. During economic expansion featuring rising consumption, production or exports, the proposed flexible policy suggests a higher reuse/recycle rate. During economic slowdown a lower rate results in lower impacts. The flexible target rates are determined in terms of annual data, including consumption, imports-exports and production. Higher environmental gains can be achieved at lower cost if the flexible policy is applied to widely consumed packaging products and materials associated with low rates, or if cleaner recycling technology is adopted.

DRAWING FOR TRAFFIC MARKING USING BIDIRECTIONAL GRADIENT-BASED DETECTION WITH MMS LIDAR INTENSITY

Directory of Open Access Journals (Sweden)

G. Takahashi

2016-06-01

Full Text Available Recently, the development of autonomous cars is accelerating on the integration of highly advanced artificial intelligence, which increases demand for a digital map with high accuracy. In particular, traffic markings are required to be precisely digitized since automatic driving utilizes them for position detection. To draw traffic markings, we benefit from Mobile Mapping Systems (MMS equipped with high-density Laser imaging Detection and Ranging (LiDAR scanners, which produces large amount of data efficiently with XYZ coordination along with reflectance intensity. Digitizing this data, on the other hand, conventionally has been dependent on human operation, which thus suffers from human errors, subjectivity errors, and low reproductivity. We have tackled this problem by means of automatic extraction of traffic marking, which partially accomplished to draw several traffic markings (G. Takahashi et al., 2014. The key idea of the method was extracting lines using the Hough transform strategically focused on changes in local reflection intensity along scan lines. However, it failed to extract traffic markings properly in a densely marked area, especially when local changing points are close each other. In this paper, we propose a bidirectional gradient-based detection method where local changing points are labelled with plus or minus group. Given that each label corresponds to the boundary between traffic markings and background, we can identify traffic markings explicitly, meaning traffic lines are differentiated correctly by the proposed method. As such, our automated method, a highly accurate and non-human-operator-dependent method using bidirectional gradient-based algorithm, can successfully extract traffic lines composed of complex shapes such as a cross walk, resulting in minimizing cost and obtaining highly accurate results.

Drawing for Traffic Marking Using Bidirectional Gradient-Based Detection with MMS LIDAR Intensity

Science.gov (United States)

Takahashi, G.; Takeda, H.; Nakamura, K.

2016-06-01

Recently, the development of autonomous cars is accelerating on the integration of highly advanced artificial intelligence, which increases demand for a digital map with high accuracy. In particular, traffic markings are required to be precisely digitized since automatic driving utilizes them for position detection. To draw traffic markings, we benefit from Mobile Mapping Systems (MMS) equipped with high-density Laser imaging Detection and Ranging (LiDAR) scanners, which produces large amount of data efficiently with XYZ coordination along with reflectance intensity. Digitizing this data, on the other hand, conventionally has been dependent on human operation, which thus suffers from human errors, subjectivity errors, and low reproductivity. We have tackled this problem by means of automatic extraction of traffic marking, which partially accomplished to draw several traffic markings (G. Takahashi et al., 2014). The key idea of the method was extracting lines using the Hough transform strategically focused on changes in local reflection intensity along scan lines. However, it failed to extract traffic markings properly in a densely marked area, especially when local changing points are close each other. In this paper, we propose a bidirectional gradient-based detection method where local changing points are labelled with plus or minus group. Given that each label corresponds to the boundary between traffic markings and background, we can identify traffic markings explicitly, meaning traffic lines are differentiated correctly by the proposed method. As such, our automated method, a highly accurate and non-human-operator-dependent method using bidirectional gradient-based algorithm, can successfully extract traffic lines composed of complex shapes such as a cross walk, resulting in minimizing cost and obtaining highly accurate results.

Bone marrow-derived cells for cardiovascular cell therapy: an optimized GMP method based on low-density gradient improves cell purity and function.

Science.gov (United States)

Radrizzani, Marina; Lo Cicero, Viviana; Soncin, Sabrina; Bolis, Sara; Sürder, Daniel; Torre, Tiziano; Siclari, Francesco; Moccetti, Tiziano; Vassalli, Giuseppe; Turchetto, Lucia

2014-09-27

Cardiovascular cell therapy represents a promising field, with several approaches currently being tested. The advanced therapy medicinal product (ATMP) for the ongoing METHOD clinical study ("Bone marrow derived cell therapy in the stable phase of chronic ischemic heart disease") consists of fresh mononuclear cells (MNC) isolated from autologous bone marrow (BM) through density gradient centrifugation on standard Ficoll-Paque. Cells are tested for safety (sterility, endotoxin), identity/potency (cell count, CD45/CD34/CD133, viability) and purity (contaminant granulocytes and platelets). BM-MNC were isolated by density gradient centrifugation on Ficoll-Paque. The following process parameters were optimized throughout the study: gradient medium density; gradient centrifugation speed and duration; washing conditions. A new manufacturing method was set up, based on gradient centrifugation on low density Ficoll-Paque, followed by 2 washing steps, of which the second one at low speed. It led to significantly higher removal of contaminant granulocytes and platelets, improving product purity; the frequencies of CD34+ cells, CD133+ cells and functional hematopoietic and mesenchymal precursors were significantly increased. The methodological optimization described here resulted in a significant improvement of ATMP quality, a crucial issue to clinical applications in cardiovascular cell therapy.

A rapid and robust gradient measurement technique using dynamic single-point imaging.

Science.gov (United States)

Jang, Hyungseok; McMillan, Alan B

2017-09-01

We propose a new gradient measurement technique based on dynamic single-point imaging (SPI), which allows simple, rapid, and robust measurement of k-space trajectory. To enable gradient measurement, we utilize the variable field-of-view (FOV) property of dynamic SPI, which is dependent on gradient shape. First, one-dimensional (1D) dynamic SPI data are acquired from a targeted gradient axis, and then relative FOV scaling factors between 1D images or k-spaces at varying encoding times are found. These relative scaling factors are the relative k-space position that can be used for image reconstruction. The gradient measurement technique also can be used to estimate the gradient impulse response function for reproducible gradient estimation as a linear time invariant system. The proposed measurement technique was used to improve reconstructed image quality in 3D ultrashort echo, 2D spiral, and multi-echo bipolar gradient-echo imaging. In multi-echo bipolar gradient-echo imaging, measurement of the k-space trajectory allowed the use of a ramp-sampled trajectory for improved acquisition speed (approximately 30%) and more accurate quantitative fat and water separation in a phantom. The proposed dynamic SPI-based method allows fast k-space trajectory measurement with a simple implementation and no additional hardware for improved image quality. Magn Reson Med 78:950-962, 2017. © 2016 International Society for Magnetic Resonance in Medicine. © 2016 International Society for Magnetic Resonance in Medicine.

IMPACTS OF GROUP-BASED SIGNAL CONTROL POLICY ON DRIVER BEHAVIOR AND INTERSECTION SAFETY

Directory of Open Access Journals (Sweden)

Keshuang TANG

2008-01-01

Full Text Available Unlike the typical stage-based policy commonly applied in Japan, the group-based control (often called movement-based in the traffic control industry in Japan refers to such a control pattern that the controller is capable of separately allocating time to each signal group instead of stage based on traffic demand. In order to investigate its applicability at signalized intersections in Japan, an intersection located in Yokkaichi City of Mie Prefecture was selected as an experimental application site by the Japan Universal Traffic Management Society (UTMS. Based on the data collected at the intersection before and after implementing the group-based control policy respectively, this study evaluated the impacts of such a policy on driver behavior and intersection safety. To specify those impacts, a few models utilizing cycle-based data were first developed to interpret the occurrence probability and rate of red-light-running (RLR. Furthermore, analyses were performed on the yellow-entry time (Ye of the last cleared vehicle and post encroachment time (PET during the phase switching. Conclusions supported that the group-based control policy, along with certain other factors, directly or indirectly influenced the RLR behavior of through and right-turn traffics. Meanwhile, it has potential safety benefits as well, indicated by the declined Ye and increased PET values.

An Experiment Using Sucrose Density Gradients in the Undergraduate Biochemistry Laboratory.

Science.gov (United States)

Turchi, Sandra L.; Weiss, Monica

1988-01-01

Describes an experiment to be performed in an undergraduate biochemistry laboratory that is based on a gradient centrifugation system employing a simple bench top centrifuge, a freezer, and frozen surcose gradient solution to separate macromolecules and subcellular components. (CW)

Identification of small-scale discontinuities based on dip-oriented gradient energy entropy coherence estimation

Science.gov (United States)

Peng, Da; Yin, Cheng

2017-09-01

Locating small-scale discontinuities is one of the most challenging geophysical tasks; these subtle geological features are significant since they are often associated with subsurface petroleum traps. Subtle faults, fractures, unconformities, reef textures, channel boundaries, thin-bed boundaries and other structural and stratigraphic discontinuities have subtle geological edges which may provide lateral variation in seismic expression. Among the different geophysical techniques available, 3D seismic discontinuity attributes are particularly useful for highlighting discontinuities in the seismic data. Traditional seismic discontinuity attributes are sensitive to noise and are not very appropriate for detecting small-scale discontinuities. Thus, we present a dip-oriented gradient energy entropy (DOGEE) coherence estimation method to detect subtle faults and structural features. The DOGEE coherence estimation method uses the gradient structure tensor (GST) algorithm to obtain local dip information and construct a gradient correlation matrix to calculate gradient energy entropy. The proposed DOGEE coherence estimation method is robust to noise, and also improves the clarity of fault edges. It is effective for small-scale discontinuity characterisation and interpretation.

Sobolev gradients and differential equations

CERN Document Server

Neuberger, J W

2010-01-01

A Sobolev gradient of a real-valued functional on a Hilbert space is a gradient of that functional taken relative to an underlying Sobolev norm. This book shows how descent methods using such gradients allow a unified treatment of a wide variety of problems in differential equations. For discrete versions of partial differential equations, corresponding Sobolev gradients are seen to be vastly more efficient than ordinary gradients. In fact, descent methods with these gradients generally scale linearly with the number of grid points, in sharp contrast with the use of ordinary gradients. Aside from the first edition of this work, this is the only known account of Sobolev gradients in book form. Most of the applications in this book have emerged since the first edition was published some twelve years ago. What remains of the first edition has been extensively revised. There are a number of plots of results from calculations and a sample MatLab code is included for a simple problem. Those working through a fair p...

A dual justification for science-based policy-making

DEFF Research Database (Denmark)

Pedersen, David Budtz

2014-01-01

Science-based policy-making has grown ever more important in recent years, in parallel with the dramatic increase in the complexity and uncertainty of the ways in which science and technology interact with society and economy at the national, regional and global level. Installing a proper framewo...

Precision bounds for gradient magnetometry with atomic ensembles

Science.gov (United States)

Apellaniz, Iagoba; Urizar-Lanz, Iñigo; Zimborás, Zoltán; Hyllus, Philipp; Tóth, Géza

2018-05-01

We study gradient magnetometry with an ensemble of atoms with arbitrary spin. We calculate precision bounds for estimating the gradient of the magnetic field based on the quantum Fisher information. For quantum states that are invariant under homogeneous magnetic fields, we need to measure a single observable to estimate the gradient. On the other hand, for states that are sensitive to homogeneous fields, a simultaneous measurement is needed, as the homogeneous field must also be estimated. We prove that for the cases studied in this paper, such a measurement is feasible. We present a method to calculate precision bounds for gradient estimation with a chain of atoms or with two spatially separated atomic ensembles. We also consider a single atomic ensemble with an arbitrary density profile, where the atoms cannot be addressed individually, and which is a very relevant case for experiments. Our model can take into account even correlations between particle positions. While in most of the discussion we consider an ensemble of localized particles that are classical with respect to their spatial degree of freedom, we also discuss the case of gradient metrology with a single Bose-Einstein condensate.

Developing Moral Sport Policies Through Act-Utilitarianism Based on Bentham’s Hedonic Calculus

Directory of Open Access Journals (Sweden)

ROBERT C. SCHNEIDER

2010-01-01

Full Text Available Moral policy can be developed and maintained in sport organizations through an approach that incorporates act-utilitarianism (AU based on Jeremy Bentham’s hedonic calculus (HC. Sport managers’ effective application of AU based on HC takes on the form of a holistic approach to moral policy development and maintenance and requires an under-standing of the parts and process of a strict adherence to AU based on HC. The traits of common sense, habits, and past experience are supported by the utilitarian views held by Bentham and Mill to accurately predict happiness and un-happiness that result from actions (Beauchamp, 1982 and are also necessary to drive a holistic approach of AU based on HC that develops and maintains moral policy in sport organizations.

Refined discrete and empirical horizontal gradients in VLBI analysis

Science.gov (United States)

Landskron, Daniel; Böhm, Johannes

2018-02-01

Missing or incorrect consideration of azimuthal asymmetry of troposphere delays is a considerable error source in space geodetic techniques such as Global Navigation Satellite Systems (GNSS) or Very Long Baseline Interferometry (VLBI). So-called horizontal troposphere gradients are generally utilized for modeling such azimuthal variations and are particularly required for observations at low elevation angles. Apart from estimating the gradients within the data analysis, which has become common practice in space geodetic techniques, there is also the possibility to determine the gradients beforehand from different data sources than the actual observations. Using ray-tracing through Numerical Weather Models (NWMs), we determined discrete gradient values referred to as GRAD for VLBI observations, based on the standard gradient model by Chen and Herring (J Geophys Res 102(B9):20489-20502, 1997. https://doi.org/10.1029/97JB01739) and also for new, higher-order gradient models. These gradients are produced on the same data basis as the Vienna Mapping Functions 3 (VMF3) (Landskron and Böhm in J Geod, 2017.https://doi.org/10.1007/s00190-017-1066-2), so they can also be regarded as the VMF3 gradients as they are fully consistent with each other. From VLBI analyses of the Vienna VLBI and Satellite Software (VieVS), it becomes evident that baseline length repeatabilities (BLRs) are improved on average by 5% when using a priori gradients GRAD instead of estimating the gradients. The reason for this improvement is that the gradient estimation yields poor results for VLBI sessions with a small number of observations, while the GRAD a priori gradients are unaffected from this. We also developed a new empirical gradient model applicable for any time and location on Earth, which is included in the Global Pressure and Temperature 3 (GPT3) model. Although being able to describe only the systematic component of azimuthal asymmetry and no short-term variations at all, even these

Reconstruction for limited-projection fluorescence molecular tomography based on projected restarted conjugate gradient normal residual.

Science.gov (United States)

Cao, Xu; Zhang, Bin; Liu, Fei; Wang, Xin; Bai, Jing

2011-12-01

Limited-projection fluorescence molecular tomography (FMT) can greatly reduce the acquisition time, which is suitable for resolving fast biology processes in vivo but suffers from severe ill-posedness because of the reconstruction using only limited projections. To overcome the severe ill-posedness, we report a reconstruction method based on the projected restarted conjugate gradient normal residual. The reconstruction results of two phantom experiments demonstrate that the proposed method is feasible for limited-projection FMT. © 2011 Optical Society of America

Spiral Gradient Coil Design for Use in Cylindrical MRI Systems.

Science.gov (United States)

Wang, Yaohui; Xin, Xuegang; Liu, Feng; Crozier, Stuart

2018-04-01

In magnetic resonance imaging, the stream function based method is commonly used in the design of gradient coils. However, this method can be prone to errors associated with the discretization of continuous current density and wire connections. In this paper, we propose a novel gradient coil design scheme that works directly in the wire space, avoiding the system errors that may appear in the stream function approaches. Specifically, the gradient coil pattern is described with dedicated spiral functions adjusted to allow the coil to produce the required field gradients in the imaging area, minimal stray field, and other engineering terms. The performance of a designed spiral gradient coil was compared with its stream-function counterpart. The numerical evaluation shows that when compared with the conventional solution, the inductance and resistance was reduced by 20.9 and 10.5%, respectively. The overall coil performance (evaluated by the figure of merit (FoM)) was improved up to 26.5% for the x -gradient coil design; for the z-gradient coil design, the inductance and resistance were reduced by 15.1 and 6.7% respectively, and the FoM was increased by 17.7%. In addition, by directly controlling the wire distributions, the spiral gradient coil design was much sparser than conventional coils.

Characterization of a texture gradient in tantalum plate

International Nuclear Information System (INIS)

Wright, S.I.; Gray, G.T. III.

1994-01-01

Clark et al. have shown that significant texture gradients can be produced in rolled tantalum plate and that the strength of the gradient is dependent on the processing path. Texture gradients are often ignored because they are time consuming to characterize and add significant complexity to materials modeling. The variation in texture through the thickness of rolled materials is most commonly measured by sectioning samples to different depths through the thickness of the plate and then measuring the texture from these section planes by X-ray diffraction. A new technique based on automatic indexing of electron backscatter diffraction patterns in the scanning electron microscope enables spatially specific orientations to be measured in a practical manner. This technique allows spatial variations in texture to be measured directly enabling gradients in texture to be investigated in more detail than previously possible. This data can be used directly in coupled finite-element/polycrystal-plasticity models to simulate the effects of variations in texture on the plastic behavior of polycrystals. This work examines the variation in texture through the thickness of a tantalum plate and its resultant effect on the compressive deformation of samples prepared from the plate. The characterization of the texture gradient using the automatic point-by-point measurement technique mentioned above is described in detail. The effect of the gradient on the plastic response of through-thickness compression tests is also discussed

Ecosystem Based Management in Transition: From Ocean Policy to Application

Science.gov (United States)

Saumweber, W. J.; Goldman, E.

2016-12-01

Ecosystem-based management (EBM) has been proposed as a means to improve resource management and stewardship for more than two decades. Over this history, its exact goals and approaches have evolved in concert with advances in science and policy, including a greater understanding of ecosystem function, valuation, and thresholds for change, along with direct reference to EBM principles in statute, regulation, and other Executive Actions. Most recently, and explicitly, the Administration's National Ocean Policy (NOP) called for the development of a Federal EBM framework that would outline principles and guidelines for implementing EBM under existing authorities. This cross-agency framework has yet to be developed, but, the NOP, and related Administration initiatives, have resulted in the practical application of EBM principles in several issue-specific policy initiatives ranging from fisheries and marine protected area management to coastal adaptation and water resource infrastructure investment. In each case, the application of EBM principles uses apparently unique policy mechanisms (e.g. marine planning, ecosystem services assessment, adaptive management, dynamic ocean management, etc.). Despite differences in terminology and policy context, each of these policy initiatives is linked at its core to concepts of integrated and adaptive management that consider broad ecosystem function and services. This practical history of EBM implementation speaks to both the challenges and opportunities in broad incorporation of EBM across diverse policy initiatives and frameworks. We suggest that the continued growth of EBM as a practical policy concept will require a move away from broad frameworks, and towards the identification of specific resource management issues and accompanying policy levers with which to address those issues. In order to promote this progression, Federal policy should recognize and articulate the diverse set of policy mechanisms encompassed under the

Stochastic parallel gradient descent based adaptive optics used for a high contrast imaging coronagraph

International Nuclear Information System (INIS)

Dong Bing; Ren Deqing; Zhang Xi

2011-01-01

An adaptive optics (AO) system based on a stochastic parallel gradient descent (SPGD) algorithm is proposed to reduce the speckle noises in the optical system of a stellar coronagraph in order to further improve the contrast. The principle of the SPGD algorithm is described briefly and a metric suitable for point source imaging optimization is given. The feasibility and good performance of the SPGD algorithm is demonstrated by an experimental system featured with a 140-actuator deformable mirror and a Hartmann-Shark wavefront sensor. Then the SPGD based AO is applied to a liquid crystal array (LCA) based coronagraph to improve the contrast. The LCA can modulate the incoming light to generate a pupil apodization mask of any pattern. A circular stepped pattern is used in our preliminary experiment and the image contrast shows improvement from 10 -3 to 10 -4.5 at an angular distance of 2λ/D after being corrected by SPGD based AO.

Subspace learning from image gradient orientations

NARCIS (Netherlands)

Tzimiropoulos, Georgios; Zafeiriou, Stefanos; Pantic, Maja

2012-01-01

We introduce the notion of subspace learning from image gradient orientations for appearance-based object recognition. As image data is typically noisy and noise is substantially different from Gaussian, traditional subspace learning from pixel intensities fails very often to estimate reliably the

Moving an Evidence-Based Policy Agenda Forward: Leadership Tips From the Field.

Science.gov (United States)

Garrett, Teresa

2018-05-01

Advancing evidence-based policy change is a leadership challenge that nurses should embrace. Key tips to ensure that evidence-based policy changes are successful at the individual, community, and population levels are offered to help nurses through the change process. The public trust in the nursing profession is a leverage point that should be used to advance the use of evidence, expedite change, and improve health for students and across communities.

The process of developing policy based on global environmental risk assessment

International Nuclear Information System (INIS)

Fisk, D.J.

1995-01-01

A brief presentation is given on developing policy based on a global environmental risk assessment. The author looks at the global warming issue as if it were a formal problem in risk assessment. He uses that framework to make one or two suggestions as to how the interaction of policy and research might evolve as the climate convention progresses

Density Gradient Stabilization of Electron Temperature Gradient Driven Turbulence in a Spherical Tokamak

International Nuclear Information System (INIS)

Ren, Y.; Kaye, S.M.; Mazzucato, E.; Guttenfelder, W.; Bell, R.E.; Domier, C.W.; LeBlanc, B.P.; Lee, K.C.; Luhmann, N.C. Jr.; Smith, D.R.; Yuh, H.

2011-01-01

In this letter we report the first clear experimental observation of density gradient stabilization of electron temperature gradient driven turbulence in a fusion plasma. It is observed that longer wavelength modes, k (perpendicular) ρ s ∼< 10, are most stabilized by density gradient, and the stabilization is accompanied by about a factor of two decrease in the plasma effective thermal diffusivity.

Quantifying the Spatiotemporal Patterns of Urbanization along Urban-Rural Gradient with a Roadscape Transect Approach: A Case Study in Shanghai, China

Directory of Open Access Journals (Sweden)

Zhonghao Zhang

2016-08-01

Full Text Available Quantifying the landscape pattern change can effectively demonstrate the ecological progresses and the consequences of urbanization. Based on remotely sensed land cover data in 1994, 2000, 2006 and a gradient analysis with landscape metrics at landscape- and class- level, we attempted to characterize the individual and entire landscape patterns of Shanghai metropolitan during the rapid urbanization. We highlighted that a roadscape transect approach that combined the buffer zone method and the transect-based approach was introduced to describe the urban-rural patterns of agricultural, residential, green, industrial, and public facilities land along the railway route. Our results of landscape metrics showed significant spatiotemporal patterns and gradient variations along the transect. The urban growth pattern in two time spans conform to the hypothesis for diffusion–coalescence processes, implying that the railway is adaptive as a gradient element to analyze the landscape patterns with urbanization. As the natural landscape was replaced by urban landscape gradually, the desakota region expanded its extent widely. Suburb areas witnessed the continual transformation from the predominantly rural landscape to peri-urban landscape. Furthermore, the gap between urban and rural areas remained large especially in public service. More reasonable urban plans and land use policies should push to make more efforts to transition from the urban-rural separation to coordinated urban-rural development. This study is a meaningful trial in demonstrating a new form of urban–rural transects to study the landscape change of large cities. By combining gradient analysis with landscape metrics, we addressed the process of urbanization both spatially and temporally, and provided a more quantitative approach to urban studies.

Nano-resonator frequency response based on strain gradient theory

International Nuclear Information System (INIS)

Miandoab, Ehsan Maani; Yousefi-Koma, Aghil; Pishkenari, Hossein Nejat; Fathi, Mohammad

2014-01-01

This paper aims to explore the dynamic behaviour of a nano-resonator under ac and dc excitation using strain gradient theory. To achieve this goal, the partial differential equation of nano-beam vibration is first converted to an ordinary differential equation by the Galerkin projection method and the lumped model is derived. Lumped parameters of the nano-resonator, such as linear and nonlinear springs and damper coefficients, are compared with those of classical theory and it is demonstrated that beams with smaller thickness display greater deviation from classical parameters. Stable and unstable equilibrium points based on classic and non-classical theories are also compared. The results show that, regarding the applied dc voltage, the dynamic behaviours expected by classical and non-classical theories are significantly different, such that one theory predicts the un-deformed shape as the stable condition, while the other theory predicts that the beam will experience bi-stability. To obtain the frequency response of the nano-resonator, a general equation including cubic and quadratic nonlinearities in addition to parametric electrostatic excitation terms is derived, and the analytical solution is determined using a second-order multiple scales method. Based on frequency response analysis, the softening and hardening effects given by two theories are investigated and compared, and it is observed that neglecting the size effect can lead to two completely different predictions in the dynamic behaviour of the resonators. The findings of this article can be helpful in the design and characterization of the size-dependent dynamic behaviour of resonators on small scales. (paper)

Gradients estimation from random points with volumetric tensor in turbulence

Science.gov (United States)

Watanabe, Tomoaki; Nagata, Koji

2017-12-01

We present an estimation method of fully-resolved/coarse-grained gradients from randomly distributed points in turbulence. The method is based on a linear approximation of spatial gradients expressed with the volumetric tensor, which is a 3 × 3 matrix determined by a geometric distribution of the points. The coarse grained gradient can be considered as a low pass filtered gradient, whose cutoff is estimated with the eigenvalues of the volumetric tensor. The present method, the volumetric tensor approximation, is tested for velocity and passive scalar gradients in incompressible planar jet and mixing layer. Comparison with a finite difference approximation on a Cartesian grid shows that the volumetric tensor approximation computes the coarse grained gradients fairly well at a moderate computational cost under various conditions of spatial distributions of points. We also show that imposing the solenoidal condition improves the accuracy of the present method for solenoidal vectors, such as a velocity vector in incompressible flows, especially when the number of the points is not large. The volumetric tensor approximation with 4 points poorly estimates the gradient because of anisotropic distribution of the points. Increasing the number of points from 4 significantly improves the accuracy. Although the coarse grained gradient changes with the cutoff length, the volumetric tensor approximation yields the coarse grained gradient whose magnitude is close to the one obtained by the finite difference. We also show that the velocity gradient estimated with the present method well captures the turbulence characteristics such as local flow topology, amplification of enstrophy and strain, and energy transfer across scales.

Influence of permittivity on gradient force exerted on Mie spheres.

Science.gov (United States)

Chen, Jun; Li, Kaikai; Li, Xiao

2018-04-01

In optical trapping, whether a particle could be stably trapped into the focus region greatly depends on the strength of the gradient force. Individual theoretical study on gradient force exerted on a Mie particle is rare because the mathematical separation of the gradient force and the scattering force in the Mie regime is difficult. Based on the recent forces separation work by Du et al. [Sci. Rep.7, 18042 (2017)SRCEC32045-232210.1038/s41598-017-17874-1], we investigate the influence of permittivity (an important macroscopic physical quantity) on the gradient force exerted on a Mie particle by cooperating numerical calculation using fast Fourier transform and analytical analysis using multipole expansion. It is revealed that gradient forces exerted on small spheres are mainly determined by the electric dipole moment except for certain permittivity with which the real part of polarizability of the electric dipole approaches zero, and gradient forces exerted on larger spheres are complex because of the superposition of the multipole moments. The classification of permittivity corresponding to different varying tendencies of gradient forces exerted on small spheres or larger Mie particles are illustrated. Absorption of particles favors the trapping of small spheres by gradient force, while it is bad for the trapping of larger particles. Moreover, the absolute values of the maximal gradient forces exerted on larger Mie particles decline greatly versus the varied imaginary part of permittivity. This work provides elaborate investigation on the different varying tendencies of gradient forces versus permittivity, which favors more accurate and free optical trapping.

The Origins of UV-optical Color Gradients in Star-forming Galaxies at z ˜ 2: Predominant Dust Gradients but Negligible sSFR Gradients

Science.gov (United States)

Liu, F. S.; Jiang, Dongfei; Faber, S. M.; Koo, David C.; Yesuf, Hassen M.; Tacchella, Sandro; Mao, Shude; Wang, Weichen; Guo, Yicheng; Fang, Jerome J.; Barro, Guillermo; Zheng, Xianzhong; Jia, Meng; Tong, Wei; Liu, Lu; Meng, Xianmin

2017-07-01

The rest-frame UV-optical (I.e., NUV - B) color is sensitive to both low-level recent star formation (specific star formation rate—sSFR) and dust. In this Letter, we extend our previous work on the origins of NUV - B color gradients in star-forming galaxies (SFGs) at z˜ 1 to those at z˜ 2. We use a sample of 1335 large (semimajor axis radius {R}{SMA}> 0\\buildrel{\\prime\\prime}\\over{.} 18) SFGs with extended UV emission out to 2{R}{SMA} in the mass range {M}* ={10}9{--}{10}11 {M}⊙ at 1.5negative NUV - B color gradients (redder centers), and their color gradients strongly increase with galaxy mass. We also show that the global rest-frame FUV - NUV color is approximately linear with {A}{{V}}, which is derived by modeling the observed integrated FUV to NIR spectral energy distributions of the galaxies. Applying this integrated calibration to our spatially resolved data, we find a negative dust gradient (more dust extinguished in the centers), which steadily becomes steeper with galaxy mass. We further find that the NUV - B color gradients become nearly zero after correcting for dust gradients regardless of galaxy mass. This indicates that the sSFR gradients are negligible and dust reddening is likely the principal cause of negative UV-optical color gradients in these SFGs. Our findings support that the buildup of the stellar mass in SFGs at Cosmic Noon is self-similar inside 2{R}{SMA}.

Gradient effects in a new class of electro-elastic bodies

Science.gov (United States)

Arvanitakis, Antonios

2018-06-01

Continuum theories for electro-elastic solids suggest the development of electric field or polarization-based models. Advanced versions of these models are the so-called gradient models, i.e., polarization gradient and electric field gradient models, which prove to be more than capable of explaining the behavior of a continuum in a wider range of length scales. In this work, implicit constitutive relations for electro-elastic bodies are considered with the introduction of polarization and electric field gradient effects. In this sense, the new class of electro-elastic bodies extends even further to account for nonlocality in constitutive equations, besides strain-limiting behavior and polarization saturation for large values of stresses and electric field, respectively. Nonlocality in constitutive equations is essential in modeling various phenomena.

Using Internet-Based Videos as Pedagogical Tools in the Social Work Policy Classroom

Directory of Open Access Journals (Sweden)

Sarabeth Leukefeld

2011-11-01

Full Text Available Students often feel disconnected from their introductory social welfare policy courses. Therefore, it is important that instructors employ engaging pedagogical methods in the classroom. A review of the literature reveals that a host of methods have been utilized to attempt to interest students in policy courses, but there is no mention of using internet-based videos in the social welfare policy classroom. This article describes how to select and use appropriate internet-based videos from websites such as YouTube and SnagFilms, to effectively engage students in social welfare policy courses. Four rules are offered for choosing videos based on emotional impact, brevity, and relevance to course topics. The selected videos should elicit students’ passions and stimulate critical thinking when used in concert with instructor-generated discussion questions, writing assignments, and small group dialogue. Examples of the process of choosing videos, discussion questions, and student reactions to the use of videos are provided.

Rapid Gradient-Echo Imaging

Science.gov (United States)

Hargreaves, Brian

2012-01-01

Gradient echo sequences are widely used in magnetic resonance imaging (MRI) for numerous applications ranging from angiography to perfusion to functional MRI. Compared with spin-echo techniques, the very short repetition times of gradient-echo methods enable very rapid 2D and 3D imaging, but also lead to complicated “steady states.” Signal and contrast behavior can be described graphically and mathematically, and depends strongly on the type of spoiling: fully balanced (no spoiling), gradient spoiling, or RF-spoiling. These spoiling options trade off between high signal and pure T1 contrast while the flip angle also affects image contrast in all cases, both of which can be demonstrated theoretically and in image examples. As with spin-echo sequences, magnetization preparation can be added to gradient-echo sequences to alter image contrast. Gradient echo sequences are widely used for numerous applications such as 3D perfusion imaging, functional MRI, cardiac imaging and MR angiography. PMID:23097185

Image defog algorithm based on open close filter and gradient domain recursive bilateral filter

Science.gov (United States)

Liu, Daqian; Liu, Wanjun; Zhao, Qingguo; Fei, Bowen

2017-11-01

To solve the problems of fuzzy details, color distortion, low brightness of the image obtained by the dark channel prior defog algorithm, an image defog algorithm based on open close filter and gradient domain recursive bilateral filter, referred to as OCRBF, was put forward. The algorithm named OCRBF firstly makes use of weighted quad tree to obtain more accurate the global atmospheric value, then exploits multiple-structure element morphological open and close filter towards the minimum channel map to obtain a rough scattering map by dark channel prior, makes use of variogram to correct the transmittance map,and uses gradient domain recursive bilateral filter for the smooth operation, finally gets recovery images by image degradation model, and makes contrast adjustment to get bright, clear and no fog image. A large number of experimental results show that the proposed defog method in this paper can be good to remove the fog , recover color and definition of the fog image containing close range image, image perspective, the image including the bright areas very well, compared with other image defog algorithms,obtain more clear and natural fog free images with details of higher visibility, what's more, the relationship between the time complexity of SIDA algorithm and the number of image pixels is a linear correlation.

High gradient RF test results of S-band and C-band cavities for medical linear accelerators

Science.gov (United States)

Degiovanni, A.; Bonomi, R.; Garlasché, M.; Verdú-Andrés, S.; Wegner, R.; Amaldi, U.

2018-05-01

TERA Foundation has proposed and designed hadrontherapy facilities based on novel linacs, i.e. high gradient linacs which accelerate either protons or light ions. The overall length of the linac, and therefore its cost, is almost inversely proportional to the average accelerating gradient. With the scope of studying the limiting factors for high gradient operation and to optimize the linac design, TERA, in collaboration with the CLIC Structure Development Group, has conducted a series of high gradient experiments. The main goals were to study the high gradient behavior and to evaluate the maximum gradient reached in 3 and 5.7 GHz structures to direct the design of medical accelerators based on high gradient linacs. This paper summarizes the results of the high power tests of 3.0 and 5.7 GHz single-cell cavities.

Low-gradient aortic stenosis.

Science.gov (United States)

Clavel, Marie-Annick; Magne, Julien; Pibarot, Philippe

2016-09-07

An important proportion of patients with aortic stenosis (AS) have a 'low-gradient' AS, i.e. a small aortic valve area (AVA gradient (gradient discrepancy raises uncertainty about the actual stenosis severity and thus about the indication for aortic valve replacement (AVR) if the patient has symptoms and/or left ventricular (LV) systolic dysfunction. The most frequent cause of low-gradient (LG) AS is the presence of a low LV outflow state, which may occur with reduced left ventricular ejection fraction (LVEF), i.e. classical low-flow, low-gradient (LF-LG), or preserved LVEF, i.e. paradoxical LF-LG. Furthermore, a substantial proportion of patients with AS may have a normal-flow, low-gradient (NF-LG) AS: i.e. a small AVA-low-gradient combination but with a normal flow. One of the most important clinical challenges in these three categories of patients with LG AS (classical LF-LG, paradoxical LF-LG, and NF-LG) is to differentiate a true-severe AS that generally benefits from AVR vs. a pseudo-severe AS that should be managed conservatively. A low-dose dobutamine stress echocardiography may be used for this purpose in patients with classical LF-LG AS, whereas aortic valve calcium scoring by multi-detector computed tomography is the preferred modality in those with paradoxical LF-LG or NF-LG AS. Although patients with LF-LG severe AS have worse outcomes than those with high-gradient AS following AVR, they nonetheless display an important survival benefit with this intervention. Some studies suggest that transcatheter AVR may be superior to surgical AVR in patients with LF-LG AS. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2016. For permissions please email: journals.permissions@oup.com.

Thickness filters for gradient based multi-material and thickness optimization of laminated composite structures

DEFF Research Database (Denmark)

Sørensen, Rene; Lund, Erik

2015-01-01

This paper presents a new gradient based method for performing discrete material and thickness optimization of laminated composite structures. The novelty in the new method lies in the application of so-called casting constraints, or thickness filters in this context, to control the thickness...... variation throughout the laminate. The filters replace the layerwise density variables with a single continuous through-the-thickness design variable. Consequently, the filters eliminate the need for having explicit constraints for preventing intermediate void through the thickness of the laminate....... Therefore, the filters reduce both the number of constraints and design variables in the optimization problem. Based upon a continuous approximation of a unit step function, the thickness filters are capable of projecting discrete 0/1 values to the underlying layerwise or ”physical” density variables which...

Assembly of multiple cell gradients directed by three-dimensional microfluidic channels.

Science.gov (United States)

Li, Yiwei; Feng, Xiaojun; Wang, Yachao; Du, Wei; Chen, Peng; Liu, Chao; Liu, Bi-Feng

2015-08-07

Active control over the cell gradient is essential for understanding biological systems and the reconstitution of the functionality of many types of tissues, particularly for organ-on-a-chip. Here, we propose a three-dimensional (3D) microfluidic strategy for generating controllable cell gradients. In this approach, a homogeneous cell suspension is loaded into a 3D stair-shaped PDMS microchannel to generate a cell gradient within 10 min by sedimentation. We demonstrate that cell gradients of various profiles (exponential and piecewise linear) can be achieved by precisely controlling the height of each layer during the fabrication. With sequential seeding, we further demonstrate the generation of two overlapping cell gradients on the same glass substrate with pre-defined designs. The cell gradient-based QD cytotoxicity assay also demonstrated that cell behaviors and resistances were regulated by the changes in cell density. These results reveal that the proposed 3D microfluidic strategy provides a simple and versatile means for establishing controllable gradients in cell density, opening up a new avenue for reconstructing functional tissues.

Optimization of Simple Monetary Policy Rules on the Base of Estimated DSGE-model

OpenAIRE

Shulgin, A.

2015-01-01

Optimization of coefficients in monetary policy rules is performed on the base of the DSGE-model with two independent monetary policy instruments estimated on the Russian data. It was found that welfare maximizing policy rules lead to inadequate result and pro-cyclical monetary policy. Optimal coefficients in Taylor rule and exchange rate rule allow to decrease volatility estimated on Russian data of 2001-2012 by about 20%. The degree of exchange rate flexibility parameter was found to be low...

Assessing of energy policies based on Turkish agriculture:

International Nuclear Information System (INIS)

Sayin, Cengiz; Nisa Mencet, M.; Ozkan, Burhan

2005-01-01

In this study, the current energy status of Turkey and the effects of national energy policies on Turkish agricultural support policies are discussed for both current and future requirements. Turkey is an energy-importing country producing 30 mtoe (million tons of oil equivalent) energy but consuming 80 mtoe. The energy import ratio of Turkey is 65-70% and the majority of this import is based on petroleum and natural gas. Furthermore, while world energy demand increases by 1.8% annually, Turkey's energy demand increases by about 8%. Although energy consumption in agriculture is much lower than the other sectors in Turkey, energy use as both input and output of agricultural sector is a very important issue due to its large agricultural potential and rural area. Total agricultural land area is 27.8 million hectares and about 66.5% of this area is devoted for cereal production. On the other hand, Turkey has over 4 million agricultural farm holdings of which 70-75% is engaged in cereal production. Machinery expenses, mainly diesel, constitute 30-50% of total variable expenses in cereal production costs. It is observed that energy policies pursued in agriculture have been directly affected by diesel prices in Turkey. Therefore, support policy tools for using diesel and electricity in agriculture are being pursued by the Turkish government

Spatially Different Tissue-Scale Diffusivity Shapes ANGUSTIFOLIA3 Gradient in Growing Leaves.

Science.gov (United States)

Kawade, Kensuke; Tanimoto, Hirokazu; Horiguchi, Gorou; Tsukaya, Hirokazu

2017-09-05

The spatial gradient of signaling molecules is pivotal for establishing developmental patterns of multicellular organisms. It has long been proposed that these gradients could arise from the pure diffusion process of signaling molecules between cells, but whether this simplest mechanism establishes the formation of the tissue-scale gradient remains unclear. Plasmodesmata are unique channel structures in plants that connect neighboring cells for molecular transport. In this study, we measured cellular- and tissue-scale kinetics of molecular transport through plasmodesmata in Arabidopsis thaliana developing leaf primordia by fluorescence recovery assays. These trans-scale measurements revealed biophysical properties of diffusive molecular transport through plasmodesmata and revealed that the tissue-scale diffusivity, but not the cellular-scale diffusivity, is spatially different along the leaf proximal-to-distal axis. We found that the gradient in cell size along the developmental axis underlies this spatially different tissue-scale diffusivity. We then asked how this diffusion-based framework functions in establishing a signaling gradient of endogenous molecules. ANGUSTIFOLIA3 (AN3) is a transcriptional co-activator, and as we have shown here, it forms a long-range signaling gradient along the leaf proximal-to-distal axis to determine a cell-proliferation domain. By genetically engineering AN3 mobility, we assessed each contribution of cell-to-cell movement and tissue growth to the distribution of the AN3 gradient. We constructed a diffusion-based theoretical model using these quantitative data to analyze the AN3 gradient formation and demonstrated that it could be achieved solely by the diffusive molecular transport in a growing tissue. Our results indicate that the spatially different tissue-scale diffusivity is a core mechanism for AN3 gradient formation. This provides evidence that the pure diffusion process establishes the formation of the long-range signaling

Graded/Gradient Porous Biomaterials

Directory of Open Access Journals (Sweden)

Xigeng Miao

2009-12-01

Full Text Available Biomaterials include bioceramics, biometals, biopolymers and biocomposites and they play important roles in the replacement and regeneration of human tissues. However, dense bioceramics and dense biometals pose the problem of stress shielding due to their high Young’s moduli compared to those of bones. On the other hand, porous biomaterials exhibit the potential of bone ingrowth, which will depend on porous parameters such as pore size, pore interconnectivity, and porosity. Unfortunately, a highly porous biomaterial results in poor mechanical properties. To optimise the mechanical and the biological properties, porous biomaterials with graded/gradient porosity, pores size, and/or composition have been developed. Graded/gradient porous biomaterials have many advantages over graded/gradient dense biomaterials and uniform or homogenous porous biomaterials. The internal pore surfaces of graded/gradient porous biomaterials can be modified with organic, inorganic, or biological coatings and the internal pores themselves can also be filled with biocompatible and biodegradable materials or living cells. However, graded/gradient porous biomaterials are generally more difficult to fabricate than uniform or homogenous porous biomaterials. With the development of cost-effective processing techniques, graded/gradient porous biomaterials can find wide applications in bone defect filling, implant fixation, bone replacement, drug delivery, and tissue engineering.

Fuzzy logic-based assessment for mapping potential infiltration areas in low-gradient watersheds.

Science.gov (United States)

Quiroz Londoño, Orlando Mauricio; Romanelli, Asunción; Lima, María Lourdes; Massone, Héctor Enrique; Martínez, Daniel Emilio

2016-07-01

This paper gives an account of the design a logic-based approach for identifying potential infiltration areas in low-gradient watersheds based on remote sensing data. This methodological framework is applied in a sector of the Pampa Plain, Argentina, which has high level of agricultural activities and large demands for groundwater supplies. Potential infiltration sites are assessed as a function of two primary topics: hydrologic and soil conditions. This model shows the state of each evaluated subwatershed respecting to its potential contribution to infiltration mainly based on easily measurable and commonly used parameters: drainage density, geomorphologic units, soil media, land-cover, slope and aspect (slope orientation). Mapped outputs from the logic model displayed 42% very low-low, 16% moderate, 41% high-very high contribution to potential infiltration in the whole watershed. Subwatersheds in the upper and lower section were identified as areas with high to very high potential infiltration according to the following media features: low drainage density (drainage plain and, dunes and beaches. Copyright © 2016 Elsevier Ltd. All rights reserved.

Analytical and policy issues in energy economics: Uses of the FRS data base

Science.gov (United States)

1981-12-01

The relevant literature concerning several major analytical and policy issues in energy economics is reviewed and criticized. The possible uses of the Financial Reporting System (FRS) data base for the analysis of energy policy issues are investigated. Certain features of FRS data suggest several ways in which the data base can be used by policy makers. FRS data are collected on the firm level, and different segments of the same firm operating in different markets can be separately identified. The methods of collection as well as FRS's elaborate data verification process guarantee a high degree of accuracy and consistency among firms.

Evidence-based policy learning: the case of the research excellence indicat

Energy Technology Data Exchange (ETDEWEB)

Hardeman, S.; Vertesy, D.

2016-07-01

Excellence is arguably the single most important concept in academia today, especially when it comes to science policy making. At the same time, however, excellence leads to a great amount of discomfort, leading some to plea for an overall rejection of the concept. The discomfort with excellence reaches its heights whenever proposals are made for measuring it. Yet, especially given the period of professionalization science policy making finds itself in, these same metrics are frequently called upon to legitimate policy interventions. Excellence and its measurement, it seems therefore, is something we can neither life with nor without. This paper offers some middle ground in the debate on excellence and its measurement for science policy purposes. Using the case of the European Commission’s Research Excellence Indicator as an example, we show how the development and use of indicators offers an opportunity for learning in science policy making. Ultimately, therefore, we show how and in what ways measuring excellence can contribute to evidence-based science policy learning in practice. (Author)

Simulations of Flame Acceleration and DDT in Mixture Composition Gradients

Science.gov (United States)

Zheng, Weilin; Kaplan, Carolyn; Houim, Ryan; Oran, Elaine

2017-11-01

Unsteady, multidimensional, fully compressible numerical simulations of methane-air in an obstructed channel with spatial gradients in equivalence ratios have been carried to determine the effects of the gradients on flame acceleration and transition to detonation. Results for gradients perpendicular to the propagation direction were considered here. A calibrated, optimized chemical-diffusive model that reproduces correct flame and detonation properties for methane-air over a range of equivalence ratios was derived from a combination of a genetic algorithm with a Nelder-Mead optimization scheme. Inhomogeneous mixtures of methane-air resulted in slower flame acceleration and longer distance to DDT. Detonations were more likely to decouple into a flame and a shock under sharper concentration gradients. Detailed analyses of temperature and equivalence ratio illustrated that vertical gradients can greatly affect the formation of hot spots that initiate detonation by changing the strength of leading shock wave and local equivalence ratio near the base of obstacles. This work is supported by the Alpha Foundation (Grant No. AFC215-20).

Avoiding vacuum arcs in high gradient normal conducting RF structures

CERN Document Server

Sjøbæk, Kyrre Ness; Adli, Erik; Grudiev, Alexej; Wuensch, Walter

In order to build the Compact LInear Collider (CLIC), accelerating structures reaching extremely high accelerating gradients are needed. Such structures have been built and tested using normal-conducting copper, powered by X-band RF power and reaching gradients of 100 MV/m and above. One phenomenon that must be avoided in order to reliably reach such gradients, is vacuum arcs or “breakdowns”. This can be accomplished by carefully designing the structure geometry such that high surface fields and large local power flows are avoided. The research presented in this thesis presents a method for optimizing the geometry of accelerating structures so that these breakdowns are made less likely, allowing the structure to operate reliably at high gradients. This was done primarily based on a phenomenological scaling model, which predicted the maximum gradient as a function of the break down rate, pulse length, and field distribution in the structure. The model is written in such a way that it allows direct comparis...

Time-domain full waveform inversion using the gradient preconditioning based on seismic wave energy: Application to the South China Sea

KAUST Repository

Mengxuan, Zhong; Jun, Tan; Peng, Song; Xiao-bo, Zhang; Chuang, Xie; Zhao-lun, Liu

2017-01-01

The gradient preconditioning algorithms based on Hessian matrices in time-domain full waveform inversion (FWI) are widely used now, but consume a lot of memory and do not fit the FWI of large models or actual seismic data well. To avoid the huge

The Potential of Tropospheric Gradients for Regional Precipitation Prediction

Science.gov (United States)

Boisits, Janina; Möller, Gregor; Wittmann, Christoph; Weber, Robert

2017-04-01

Changes of temperature and humidity in the neutral atmosphere cause variations in tropospheric path delays and tropospheric gradients. By estimating zenith wet delays (ZWD) and gradients using a GNSS reference station network the obtained time series provide information about spatial and temporal variations of water vapour in the atmosphere. Thus, GNSS-based tropospheric parameters can contribute to the forecast of regional precipitation events. In a recently finalized master thesis at TU Wien the potential of tropospheric gradients for weather prediction was investigated. Therefore, ZWD and gradient time series at selected GNSS reference stations were compared to precipitation data over a period of six months (April to September 2014). The selected GNSS stations form two test areas within Austria. All required meteorological data was provided by the Central Institution for Meteorology and Geodynamics (ZAMG). Two characteristics in ZWD and gradient time series can be anticipated in case of an approaching weather front. First, an induced asymmetry in tropospheric delays results in both, an increased magnitude of the gradient and in gradients pointing towards the weather front. Second, an increase in ZWD reflects the increased water vapour concentration right before a precipitation event. To investigate these characteristics exemplary test events were processed. On the one hand, the sequence of the anticipated increase in ZWD at each GNSS station obtained by cross correlation of the time series indicates the direction of the approaching weather front. On the other hand, the corresponding peak in gradient time series allows the deduction of the direction of movement as well. To verify the results precipitation data from ZAMG was used. It can be deduced, that tropospheric gradients show high potential for predicting precipitation events. While ZWD time series rather indicate the orientation of the air mass boundary, gradients rather indicate the direction of movement

Thermal gradients caused by the CANDU moderator circulation

International Nuclear Information System (INIS)

Mohindra, V.K.; Vartolomei, M.A.; Scharfenberg, R.

2008-01-01

The heavy water moderator circulation system of a CANDU reactor, maintains calandria moderator temperature at power-dependent design values. The temperature differentials between the moderator and the cooler heavy water entering the calandria generate thermal gradients in the reflector and moderator. The resultant small changes in thermal neutron population are detected by the out-of-core ion chambers as small, continuous fluctuations of the Log Rate signals. The impact of the thermal gradients on the frequency of the High Log Rate fluctuations and their amplitude is relatively more pronounced for Bruce A as compared to Bruce B reactors. The root cause of the Log Rate fluctuations was investigated using Bruce Power operating plant information data and the results of the investigation support the interpretation based on the thermal gradient phenomenon. (author)

Gradient index metamaterials realized by drilling hole arrays

International Nuclear Information System (INIS)

Mei Zhonglei; Cui Tiejun; Bai Jing

2010-01-01

Gradient index metamaterials have wide applications in the microwave and optical fields. Based on the quasi-static theory, such materials at the microwave band have been realized by drilling hole arrays on ordinary dielectric materials. As applications of the gradient index metamaterials, novel devices including a 45 0 dielectric wave-bending structure, a 16 0 wave-steering lens and a microwave focusing lens are designed and fabricated. Field mapping measurements validate the proposed gradient index metamaterials and the device designs. The method can be directly and easily extended to the design of cloaks, various lenses, beam shifters and beam-steering devices. It can also be applied in the optical band as long as quasi-static conditions are satisfied. The method and the devices may find applications in integrated circuit systems.

Pilling evaluation of patterned fabrics based on a gradient field method

Czech Academy of Sciences Publication Activity Database

Techniková, L.; Tunák, M.; Janáček, Jiří

2016-01-01

Roč. 41, č. 1 (2016), s. 97-101 ISSN 0971-0426 Institutional support: RVO:67985823 Keywords : 3D surface reconstruction * fabric pilling * gradient field method * patterned fabric * pills detection Subject RIV: JS - Reliability ; Quality Management, Testing Impact factor: 0.430, year: 2016

Versatile gradients of chemistry, bound ligands and nanoparticles on alumina nanopore arrays

International Nuclear Information System (INIS)

Michelmore, Andrew; Poh, Zihan; Goreham, Renee V; Short, Robert D; Vasilev, Krasimir; Mierczynska, Agnieszka; Losic, Dusan

2011-01-01

Nanoporous alumina (PA) arrays produced by self-ordering growth, using electrochemical anodization, have been extensively explored for potential applications based upon the unique thermal, mechanical and structural properties, and high surface-to-volume ratio of these materials. However, the potential applications and functionality of these materials may be further extended by molecular-level engineering of the surface of the pore rims. In this paper we present a method for the generation of chemical gradients on the surface of PA arrays based upon plasma co-polymerization of two monomers. We further extend these chemical gradients, which are also gradients of surface charge, to those of bound ligands and number density gradients of nanoparticles. The latter represent a highly exotic new class of materials, comprising aligned PA, capped by gold nanoparticles around the rim of the pores. Gradients of chemistry, ligands and nanoparticles generated by our method retain the porous structure of the substrate, which is important in applications that take advantage of the inherent properties of these materials. This method can be readily extended to other porous materials.

Versatile gradients of chemistry, bound ligands and nanoparticles on alumina nanopore arrays

Energy Technology Data Exchange (ETDEWEB)

Michelmore, Andrew; Poh, Zihan; Goreham, Renee V; Short, Robert D; Vasilev, Krasimir [Mawson Institute, University of South Australia, Mawson Lakes, SA 5095, Adelaide (Australia); Mierczynska, Agnieszka; Losic, Dusan, E-mail: Krasimir.vasilev@unisa.edu.au [Ian Wark Research Institute, University of South Australia, Mawson Lakes, SA 5095, Adelaide (Australia)

2011-10-14

Nanoporous alumina (PA) arrays produced by self-ordering growth, using electrochemical anodization, have been extensively explored for potential applications based upon the unique thermal, mechanical and structural properties, and high surface-to-volume ratio of these materials. However, the potential applications and functionality of these materials may be further extended by molecular-level engineering of the surface of the pore rims. In this paper we present a method for the generation of chemical gradients on the surface of PA arrays based upon plasma co-polymerization of two monomers. We further extend these chemical gradients, which are also gradients of surface charge, to those of bound ligands and number density gradients of nanoparticles. The latter represent a highly exotic new class of materials, comprising aligned PA, capped by gold nanoparticles around the rim of the pores. Gradients of chemistry, ligands and nanoparticles generated by our method retain the porous structure of the substrate, which is important in applications that take advantage of the inherent properties of these materials. This method can be readily extended to other porous materials.

THE IMAGE REGISTRATION OF FOURIER-MELLIN BASED ON THE COMBINATION OF PROJECTION AND GRADIENT PREPROCESSING

Directory of Open Access Journals (Sweden)

D. Gao

2017-09-01

Full Text Available Image registration is one of the most important applications in the field of image processing. The method of Fourier Merlin transform, which has the advantages of high precision and good robustness to change in light and shade, partial blocking, noise influence and so on, is widely used. However, not only this method can’t obtain the unique mutual power pulse function for non-parallel image pairs, even part of image pairs also can’t get the mutual power function pulse. In this paper, an image registration method based on Fourier-Mellin transformation in the view of projection-gradient preprocessing is proposed. According to the projection conformational equation, the method calculates the matrix of image projection transformation to correct the tilt image; then, gradient preprocessing and Fourier-Mellin transformation are performed on the corrected image to obtain the registration parameters. Eventually, the experiment results show that the method makes the image registration of Fourier-Mellin transformation not only applicable to the registration of the parallel image pairs, but also to the registration of non-parallel image pairs. What’s more, the better registration effect can be obtained

Evaluation of stress gradient by x-ray stress measurement based on change in angle phi

International Nuclear Information System (INIS)

Sasaki, Toshihiko; Kuramoto, Makoto; Yoshioka, Yasuo.

1985-01-01

A new principle of X-ray stress evaluation for a sample with steep stress gradient has been prosed. The feature of this method is that the stress is determined by using so-called phi-method based on the change of phi-angle and thus has no effect on the penetration depth of X-rays. The procedure is as follows; firstly, an average stress within the penetration depth of X-rays is determined by changing only phi-angle under a fixed psi-angle, and then a distribution of the average stress vs. the penetration depth of X-rays is detected by repeating the similar procedure at different psi-angles. The following conclusions were found out as the result of residual stress measurements on a carbon steel of type S 55 C polished by emery paper. This method is practical enough to use for a plane stress problem. And the assumption of a linear stress gradient adopted in the authors' previous investigations is valid. In case of a triaxial stress analysis, this method is effective for the solution of three shearing stresses. However, three normal stresses can not be solved perfectly except particular psi-angles. (author)

Gradient-Based Optimization of Wind Farms with Different Turbine Heights: Preprint

Energy Technology Data Exchange (ETDEWEB)

Stanley, Andrew P. J.; Thomas, Jared; Ning, Andrew; Annoni, Jennifer; Dykes, Katherine; Fleming, Paul

2017-05-08

Turbine wakes reduce power production in a wind farm. Current wind farms are generally built with turbines that are all the same height, but if wind farms included turbines with different tower heights, the cost of energy (COE) may be reduced. We used gradient-based optimization to demonstrate a method to optimize wind farms with varied hub heights. Our study includes a modified version of the FLORIS wake model that accommodates three-dimensional wakes integrated with a tower structural model. Our purpose was to design a process to minimize the COE of a wind farm through layout optimization and varying turbine hub heights. Results indicate that when a farm is optimized for layout and height with two separate height groups, COE can be lowered by as much as 5%-9%, compared to a similar layout and height optimization where all the towers are the same. The COE has the best improvement in farms with high turbine density and a low wind shear exponent.

Designing a climate change policy for the international maritime transport sector: Market-based measures and technological options for global and regional policy actions

International Nuclear Information System (INIS)

Miola, A.; Marra, M.; Ciuffo, B.

2011-01-01

The international maritime transport sector has a significant abatement potential and some technical improvements that reduce GHG emissions would already be profitable without any policy in place. This paper analyses in-depth the limits and opportunities of policy options currently under consideration at the international level to stimulate the sector to reduce its GHG emissions. In particular, in order for the maritime transport sector to become more environmentally friendly, the flexible nature of international market-based measures and the European Union Emission Trading Scheme provide a definite window of opportunity without placing unnecessary high burden on the sector. However, the development of a regional policy, such as at European level, for the international maritime transport sector faces several obstacles: allocation of emissions, carbon leakage, permit allocation, treatment of the great variety in ship type, size and usage, and transaction cost. Global market-based policies could overcome most of these challenges. This paper provides an in-depth analysis of the policy instruments currently under discussion to reduce the sector's burden on the environment, and focuses on economic theory, legal principles, technological options, and the political framework that together make up the basis of decision-making regarding the international maritime transport sector's climate change policies. - Highlights: → Technologies for a more environmental friendly maritime transport sector and their cost-effectiveness. → How to combine ambitious CO 2 reduction goals with a sector-wide market-based policy. → Permits should be auctioned frequently and small emitters have to be excluded. → Inclusion of shipping in the EU ETS causes carbon leakage, so the policy should aim at expansion.

Sector-based political analysis of energy transition: Green shift in the forest policy regime in France

International Nuclear Information System (INIS)

Sergent, Arnaud

2014-01-01

This article examines energy transition political process from a sector-based approach, through the analysis of recent shift in the French forest policy regime. We demonstrate that, since 2007, energy transition policies have led to a harvesting turn within the French forest policy framework, meaning that priority is given to wood mobilisation, mainly for biomass uses. In addition, our findings suggest that the political authority wielded by the state over forest policy has shifted from forest administrative services to energy agencies and local authorities. Finally, we show that, although implementation of the harvesting turn is a cause of sectoral and inter-sectoral tensions, energy transition challenge also contributes to a process of (re)institutionalisation of mediation relationships among forestry stakeholders and wood-based industries representatives. The article concludes by arguing that sectors should retain relevant institutional frameworks for actors when choosing political arrangements required for implementing energy transition policy. - Highlights: • Implementing energy transition policy potentially challenges sector-based politics. • We propose a policy regime framework and socio-political investigations. • We analyse the political impact of energy transition policy on French forest sector. • Shifts occur in sectoral policy framework, authority, and mediation relationships

What Is the Best Way to Contour Lung Tumors on PET Scans? Multiobserver Validation of a Gradient-Based Method Using a NSCLC Digital PET Phantom

Energy Technology Data Exchange (ETDEWEB)

Werner-Wasik, Maria, E-mail: Maria.Werner-wasik@jeffersonhospital.org [Department of Radiation Oncology, Thomas Jefferson University Hospital, Philadelphia, PA (United States); Nelson, Arden D. [MIM Software Inc., Cleveland, OH (United States); Choi, Walter [Department of Radiation Oncology, UPMC Health Systems, Pittsburgh, PA (United States); Arai, Yoshio [Department of Radiation Oncology, Beth Israel Medical Center, New York, NY (Israel); Faulhaber, Peter F. [University Hospitals Case Medical Center, Cleveland, OH (United States); Kang, Patrick [Department of Radiology, Beth Israel Medical Center, New York, NY (Israel); Almeida, Fabio D. [Division of Nuclear Medicine, University of Arizona Health Sciences Center, Tucson, AZ (United States); Xiao, Ying; Ohri, Nitin [Department of Radiation Oncology, Thomas Jefferson University Hospital, Philadelphia, PA (United States); Brockway, Kristin D.; Piper, Jonathan W.; Nelson, Aaron S. [MIM Software Inc., Cleveland, OH (United States)

2012-03-01

Purpose: To evaluate the accuracy and consistency of a gradient-based positron emission tomography (PET) segmentation method, GRADIENT, compared with manual (MANUAL) and constant threshold (THRESHOLD) methods. Methods and Materials: Contouring accuracy was evaluated with sphere phantoms and clinically realistic Monte Carlo PET phantoms of the thorax. The sphere phantoms were 10-37 mm in diameter and were acquired at five institutions emulating clinical conditions. One institution also acquired a sphere phantom with multiple source-to-background ratios of 2:1, 5:1, 10:1, 20:1, and 70:1. One observer segmented (contoured) each sphere with GRADIENT and THRESHOLD from 25% to 50% at 5% increments. Subsequently, seven physicians segmented 31 lesions (7-264 mL) from 25 digital thorax phantoms using GRADIENT, THRESHOLD, and MANUAL. Results: For spheres <20 mm in diameter, GRADIENT was the most accurate with a mean absolute % error in diameter of 8.15% (10.2% SD) compared with 49.2% (51.1% SD) for 45% THRESHOLD (p < 0.005). For larger spheres, the methods were statistically equivalent. For varying source-to-background ratios, GRADIENT was the most accurate for spheres >20 mm (p < 0.065) and <20 mm (p < 0.015). For digital thorax phantoms, GRADIENT was the most accurate (p < 0.01), with a mean absolute % error in volume of 10.99% (11.9% SD), followed by 25% THRESHOLD at 17.5% (29.4% SD), and MANUAL at 19.5% (17.2% SD). GRADIENT had the least systematic bias, with a mean % error in volume of -0.05% (16.2% SD) compared with 25% THRESHOLD at -2.1% (34.2% SD) and MANUAL at -16.3% (20.2% SD; p value <0.01). Interobserver variability was reduced using GRADIENT compared with both 25% THRESHOLD and MANUAL (p value <0.01, Levene's test). Conclusion: GRADIENT was the most accurate and consistent technique for target volume contouring. GRADIENT was also the most robust for varying imaging conditions. GRADIENT has the potential to play an important role for tumor delineation in

Policy recommendations for addressing privacy challenges associated with cell-based research and interventions.

Science.gov (United States)

Ogbogu, Ubaka; Burningham, Sarah; Ollenberger, Adam; Calder, Kathryn; Du, Li; El Emam, Khaled; Hyde-Lay, Robyn; Isasi, Rosario; Joly, Yann; Kerr, Ian; Malin, Bradley; McDonald, Michael; Penney, Steven; Piat, Gayle; Roy, Denis-Claude; Sugarman, Jeremy; Vercauteren, Suzanne; Verhenneman, Griet; West, Lori; Caulfield, Timothy

2014-02-03

The increased use of human biological material for cell-based research and clinical interventions poses risks to the privacy of patients and donors, including the possibility of re-identification of individuals from anonymized cell lines and associated genetic data. These risks will increase as technologies and databases used for re-identification become affordable and more sophisticated. Policies that require ongoing linkage of cell lines to donors' clinical information for research and regulatory purposes, and existing practices that limit research participants' ability to control what is done with their genetic data, amplify the privacy concerns. To date, the privacy issues associated with cell-based research and interventions have not received much attention in the academic and policymaking contexts. This paper, arising out of a multi-disciplinary workshop, aims to rectify this by outlining the issues, proposing novel governance strategies and policy recommendations, and identifying areas where further evidence is required to make sound policy decisions. The authors of this paper take the position that existing rules and norms can be reasonably extended to address privacy risks in this context without compromising emerging developments in the research environment, and that exceptions from such rules should be justified using a case-by-case approach. In developing new policies, the broader framework of regulations governing cell-based research and related areas must be taken into account, as well as the views of impacted groups, including scientists, research participants and the general public. This paper outlines deliberations at a policy development workshop focusing on privacy challenges associated with cell-based research and interventions. The paper provides an overview of these challenges, followed by a discussion of key themes and recommendations that emerged from discussions at the workshop. The paper concludes that privacy risks associated with cell-based

An alternative treatment of phenomenological higher-order strain-gradient plasticity theory

DEFF Research Database (Denmark)

Kuroda, Mitsutoshi; Tvergaard, Viggo

2010-01-01

strain is discussed, applying a dislocation theory-based consideration. Then, a differential equation for the equivalent plastic strain-gradient is introduced as an additional governing equation. Its weak form makes it possible to deduce and impose extra boundary conditions for the equivalent plastic...... strain. A connection between the present treatment and strain-gradient theories based on an extended virtual work principle is discussed. Furthermore, a numerical implementation and analysis of constrained simple shear of a thin strip are presented....

Preconditioned stochastic gradient descent optimisation for monomodal image registration

NARCIS (Netherlands)

Klein, S.; Staring, M.; Andersson, J.P.; Pluim, J.P.W.; Fichtinger, G.; Martel, A.; Peters, T.

2011-01-01

We present a stochastic optimisation method for intensity-based monomodal image registration. The method is based on a Robbins-Monro stochastic gradient descent method with adaptive step size estimation, and adds a preconditioning matrix. The derivation of the pre-conditioner is based on the

METALLICITY GRADIENTS OF THICK DISK DWARF STARS

Energy Technology Data Exchange (ETDEWEB)

Carrell, Kenneth; Chen Yuqin; Zhao Gang, E-mail: carrell@nao.cas.cn [Key Laboratory of Optical Astronomy, National Astronomical Observatories, Chinese Academy of Sciences, Beijing 100012 (China)

2012-12-01

We examine the metallicity distribution of the Galactic thick disk using F, G, and K dwarf stars selected from the Sloan Digital Sky Survey, Data Release 8. Using the large sample of dwarf stars with proper motions and spectroscopically determined stellar parameters, metallicity gradients in the radial direction for various heights above the Galactic plane and in the vertical direction for various radial distances from the Galaxy center have been found. In particular, we find a vertical metallicity gradient of -0.113 {+-} 0.010 (-0.125 {+-} 0.008) dex kpc{sup -1} using an isochrone (photometric) distance determination in the range 1 kpc <|Z| < 3 kpc, which is the vertical height range most consistent with the thick disk of our Galaxy. In the radial direction, we find metallicity gradients between +0.02 and +0.03 dex kpc{sup -1} for bins in the vertical direction between 1 kpc <|Z| < 3 kpc. Both of these results agree with similar values determined from other populations of stars, but this is the first time a radial metallicity gradient for the thick disk has been found at these vertical heights. We are also able to separate thin and thick disk stars based on kinematic and spatial probabilities in the vertical height range where there is significant overlap of these two populations. This should aid further studies of the metallicity gradients of the disk for vertical heights lower than those studied here but above the solar neighborhood. Metallicity gradients in the thin and thick disks are important probes into possible formation scenarios for our Galaxy and a consistent picture is beginning to emerge from results using large spectroscopic surveys, such as the ones presented here.

Strain gradient effects on cyclic plasticity

DEFF Research Database (Denmark)

Niordson, Christian Frithiof; Legarth, Brian Nyvang

2010-01-01

Size effects on the cyclic shear response are studied numerically using a recent higher order strain gradient visco-plasticity theory accounting for both dissipative and energetic gradient hardening. Numerical investigations of the response under cyclic pure shear and shear of a finite slab between...... rigid platens have been carried out, using the finite element method. It is shown for elastic–perfectly plastic solids how dissipative gradient effects lead to increased yield strength, whereas energetic gradient contributions lead to increased hardening as well as a Bauschinger effect. For linearly...... hardening materials it is quantified how dissipative and energetic gradient effects promote hardening above that of conventional predictions. Usually, increased hardening is attributed to energetic gradient effects, but here it is found that also dissipative gradient effects lead to additional hardening...

What Is the Best Way to Contour Lung Tumors on PET Scans? Multiobserver Validation of a Gradient-Based Method Using a NSCLC Digital PET Phantom

International Nuclear Information System (INIS)

Werner-Wasik, Maria; Nelson, Arden D.; Choi, Walter; Arai, Yoshio; Faulhaber, Peter F.; Kang, Patrick; Almeida, Fabio D.; Xiao, Ying; Ohri, Nitin; Brockway, Kristin D.; Piper, Jonathan W.; Nelson, Aaron S.

2012-01-01

Purpose: To evaluate the accuracy and consistency of a gradient-based positron emission tomography (PET) segmentation method, GRADIENT, compared with manual (MANUAL) and constant threshold (THRESHOLD) methods. Methods and Materials: Contouring accuracy was evaluated with sphere phantoms and clinically realistic Monte Carlo PET phantoms of the thorax. The sphere phantoms were 10–37 mm in diameter and were acquired at five institutions emulating clinical conditions. One institution also acquired a sphere phantom with multiple source-to-background ratios of 2:1, 5:1, 10:1, 20:1, and 70:1. One observer segmented (contoured) each sphere with GRADIENT and THRESHOLD from 25% to 50% at 5% increments. Subsequently, seven physicians segmented 31 lesions (7–264 mL) from 25 digital thorax phantoms using GRADIENT, THRESHOLD, and MANUAL. Results: For spheres 20 mm (p < 0.065) and <20 mm (p < 0.015). For digital thorax phantoms, GRADIENT was the most accurate (p < 0.01), with a mean absolute % error in volume of 10.99% (11.9% SD), followed by 25% THRESHOLD at 17.5% (29.4% SD), and MANUAL at 19.5% (17.2% SD). GRADIENT had the least systematic bias, with a mean % error in volume of –0.05% (16.2% SD) compared with 25% THRESHOLD at –2.1% (34.2% SD) and MANUAL at –16.3% (20.2% SD; p value <0.01). Interobserver variability was reduced using GRADIENT compared with both 25% THRESHOLD and MANUAL (p value <0.01, Levene’s test). Conclusion: GRADIENT was the most accurate and consistent technique for target volume contouring. GRADIENT was also the most robust for varying imaging conditions. GRADIENT has the potential to play an important role for tumor delineation in radiation therapy planning and response assessment.

Full Waveform Inversion Using an Energy-Based Objective Function with Efficient Calculation of the Gradient

KAUST Repository

Choi, Yun Seok

2017-05-26

Full waveform inversion (FWI) using an energy-based objective function has the potential to provide long wavelength model information even without low frequency in the data. However, without the back-propagation method (adjoint-state method), its implementation is impractical for the model size of general seismic survey. We derive the gradient of the energy-based objective function using the back-propagation method to make its FWI feasible. We also raise the energy signal to the power of a small positive number to properly handle the energy signal imbalance as a function of offset. Examples demonstrate that the proposed FWI algorithm provides a convergent long wavelength structure model even without low-frequency information, which can be used as a good starting model for the subsequent conventional FWI.

Mixed model phase evolution for correction of magnetic field inhomogeneity effects in 3D quantitative gradient echo-based MRI

DEFF Research Database (Denmark)

Fatnassi, Chemseddine; Boucenna, Rachid; Zaidi, Habib

2017-01-01

PURPOSE: In 3D gradient echo magnetic resonance imaging (MRI), strong field gradients B0macro are visually observed at air/tissue interfaces. At low spatial resolution in particular, the respective field gradients lead to an apparent increase in intravoxel dephasing, and subsequently, to signal...... loss or inaccurate R2* estimates. If the strong field gradients are measured, their influence can be removed by postprocessing. METHODS: Conventional corrections usually assume a linear phase evolution with time. For high macroscopic gradient inhomogeneities near the edge of the brain...

Nonlinear behavior of capacitive micro-beams based on strain gradient theory

International Nuclear Information System (INIS)

Fathalilou, Mohammad; Sadeghi, Morteza; Rezazadeh, Ghader

2014-01-01

This paper studies the size dependent behavior of materials in MEMS structures. This behavior becomes noticeable for a structure when the characteristic size such as thickness or diameter is close to its internal length-scale parameter and is insignificant for the high ratio of the characteristic size to the length-scale parameter, which is the case of the silicon base micro-beams. However, in some types of micro-beams like gold or nickel bases, the size dependent effect cannot be overlooked. In such cases, ignoring this behavior in modeling will lead to incorrect results. Some previous researchers have applied classic beam theory on their models and imposed a considerable hypothetical value of residual stress to match their theoretical results with the experimental ones. The equilibrium positions or fixed points of the gold and nickel micro-beams are obtained and shown that for a given DC voltage, there is a considerable difference between the obtained fixed points using classic beam theory, modified couple stress theory, and modified strain gradient theory. In addition, it is shown that the calculated static and dynamic pull-in voltages using higher order theories are much closer to the experimental results and are higher several times than those obtained by classic beam theory.

Travelling gradient thermocouple calibration

International Nuclear Information System (INIS)

Broomfield, G.H.

1975-01-01

A short discussion of the origins of the thermocouple EMF is used to re-introduce the idea that the Peltier and Thompson effects are indistinguishable from one another. Thermocouples may be viewed as devices which generate an EMF at junctions or as integrators of EMF's developed in thermal gradients. The thermal gradient view is considered the more appropriate, because of its better accord with theory and behaviour, the correct approach to calibration, and investigation of service effects is immediately obvious. Inhomogeneities arise in thermocouples during manufacture and in service. The results of travelling gradient measurements are used to show that such effects are revealed with a resolution which depends on the length of the gradient although they may be masked during simple immersion calibration. Proposed tests on thermocouples irradiated in a nuclear reactor are discussed

Exploring Dutch surgeons' views on volume-based policies: a qualitative interview study.

Science.gov (United States)

Mesman, Roos; Faber, Marjan J; Westert, Gert P; Berden, Bart

2018-01-01

Objective In many countries, the evidence for volume-outcome associations in surgery has been transferred into policy. Despite the large body of research that exists on the topic, qualitative studies aimed at surgeons' views on, and experiences with, these volume-based policies are lacking. We interviewed Dutch surgeons to gain more insight into the implications of volume-outcome policies for daily clinical practice, as input for effective surgical quality improvement. Methods Semi-structured interviews were conducted with 20 purposively selected surgeons from a stratified sample for hospital type and speciality. The interviews were recorded, transcribed verbatim and underwent inductive content analysis. Results Two overarching themes were inductively derived from the data: (1) minimum volume standards and (2) implications of volume-based policies. Although surgeons acknowledged the premise 'more is better', they were critical about the validity and underlying evidence for minimum volume standards. Patients often inquire about caseload, which is met with both understanding and discomfort. Surgeons offered many examples of controversies surrounding the process of determining thresholds as well as the ways in which health insurers use volume as a purchasing criterion. Furthermore, being held accountable for caseload may trigger undesired strategic behaviour, such as unwarranted operations. Volume-based policies also have implications for the survival of low-volume providers and affect patient travel times, although the latter is not necessarily problematic in the Dutch context. Conclusions Surgeons in this study acknowledged that more volume leads to better quality. However, validity issues, undesired strategic behaviour and the ways in which minimum volume standards are established and applied have made surgeons critical of current policy practice. These findings suggest that volume remains a controversial quality measure and causes polarization that is not

Self-organization of intracellular gradients during mitosis

Directory of Open Access Journals (Sweden)

Fuller Brian G

2010-01-01

Full Text Available Abstract Gradients are used in a number of biological systems to transmit spatial information over a range of distances. The best studied are morphogen gradients where information is transmitted over many cell lengths. Smaller mitotic gradients reflect the need to organize several distinct events along the length of the mitotic spindle. The intracellular gradients that characterize mitosis are emerging as important regulatory paradigms. Intracellular gradients utilize intrinsic auto-regulatory feedback loops and diffusion to establish stable regions of activity within the mitotic cytosol. We review three recently described intracellular mitotic gradients. The Ran GTP gradient with its elaborate cascade of nuclear transport receptors and cargoes is the best characterized, yet the dynamics underlying the robust gradient of Ran-GTP have received little attention. Gradients of phosphorylation have been observed on Aurora B kinase substrates both before and after anaphase onset. In both instances the phosphorylation gradient appears to result from a soluble gradient of Aurora B kinase activity. Regulatory properties that support gradient formation are highlighted. Intracellular activity gradients that regulate localized mitotic events bare several hallmarks of self-organizing biologic systems that designate spatial information during pattern formation. Intracellular pattern formation represents a new paradigm in mitotic regulation.

A penalized linear and nonlinear combined conjugate gradient method for the reconstruction of fluorescence molecular tomography.

Science.gov (United States)

Shang, Shang; Bai, Jing; Song, Xiaolei; Wang, Hongkai; Lau, Jaclyn

2007-01-01

Conjugate gradient method is verified to be efficient for nonlinear optimization problems of large-dimension data. In this paper, a penalized linear and nonlinear combined conjugate gradient method for the reconstruction of fluorescence molecular tomography (FMT) is presented. The algorithm combines the linear conjugate gradient method and the nonlinear conjugate gradient method together based on a restart strategy, in order to take advantage of the two kinds of conjugate gradient methods and compensate for the disadvantages. A quadratic penalty method is adopted to gain a nonnegative constraint and reduce the illposedness of the problem. Simulation studies show that the presented algorithm is accurate, stable, and fast. It has a better performance than the conventional conjugate gradient-based reconstruction algorithms. It offers an effective approach to reconstruct fluorochrome information for FMT.

Databases as policy instruments. About extending networks as evidence-based policy

Directory of Open Access Journals (Sweden)

Stoevelaar Herman

2007-12-01

Full Text Available Abstract Background This article seeks to identify the role of databases in health policy. Access to information and communication technologies has changed traditional relationships between the state and professionals, creating new systems of surveillance and control. As a result, databases may have a profound effect on controlling clinical practice. Methods We conducted three case studies to reconstruct the development and use of databases as policy instruments. Each database was intended to be employed to control the use of one particular pharmaceutical in the Netherlands (growth hormone, antiretroviral drugs for HIV and Taxol, respectively. We studied the archives of the Dutch Health Insurance Board, conducted in-depth interviews with key informants and organized two focus groups, all focused on the use of databases both in policy circles and in clinical practice. Results Our results demonstrate that policy makers hardly used the databases, neither for cost control nor for quality assurance. Further analysis revealed that these databases facilitated self-regulation and quality assurance by (national bodies of professionals, resulting in restrictive prescription behavior amongst physicians. Conclusion The databases fulfill control functions that were formerly located within the policy realm. The databases facilitate collaboration between policy makers and physicians, since they enable quality assurance by professionals. Delegating regulatory authority downwards into a network of physicians who control the use of pharmaceuticals seems to be a good alternative for centralized control on the basis of monitoring data.

Place-based innovation in Cohesion Policy: meeting and measuring the challenges

Directory of Open Access Journals (Sweden)

Alys Solly

2016-01-01

Full Text Available This paper, prepared in conjunction with the European Union’s Open Days 2015, examines current Cohesion Policy in terms of its place-based logic, a key aspect of the new Smart Specialisation strategy platform. After discussing changing notions of urbanization and governance, which seem to be shifting Cohesion Policy towards a more performance-oriented analysis of its outcomes, the paper focuses on the question of identifying an appropriate set of indicators and measuring framework. It suggests that measurements of Cohesion Policy performance should analyse the outcomes and indicators, as well as the European and national data sources and statistics, through the lens of effectiveness and well-being.

Value-based Q(s,S) policy for joint replenishments

DEFF Research Database (Denmark)

Johansen, Søren Glud; Thorstenson, Anders

replenishment order is issued, if the expected cost of ordering immediately according to the (s, S) policy is less than the expected cost of deferring the order until the next demand or until the level Q is reached. We use simulation to evaluate our policy. Applying the value-based Q(s, S) policy to a standard...... set of 12-item numerical examples from the literature, the long-run average cost of the best known solution is reduced by approximately 1%. Further examples are also investigated and in some cases for which the cost structure implies a high service level, the cost reduction exceeds 10% of the cost...

Combined use of headwind ramps and gradients based on LIDAR data in the alerting of low-level windshear/turbulence

Energy Technology Data Exchange (ETDEWEB)

Chan, P.W.; Hon, K.K. [Hong Kong Observatory, Hong Kong (China); Shin, D.K. [Korea Meteorological Administration, Seoul (Korea, Republic of)

2011-12-15

A sophisticated algorithm based on the detection of significant headwind changes, the so-called ''windshear ramps'', has been developed by the Hong Kong Observatory (HKO) in the alerting of low-level windshear using LIDAR data. The method, named as LIWAS (LIDAR Windshear Alerting System), is particularly efficient in detecting airflow disturbances in the vicinity of the Hong Kong International Airport (HKIA) due to terrain disruption of the background wind. It puts emphasis on sustained headwind change from one level to another level. However, for terrain-disrupted airflow, there may also be abrupt wind changes of smaller spatial scales (e.g. over a distance of a few hundred metres) embedded in the windshear ramp which typically spans a larger spatial scale (e.g. over a couple of kilometres). As such, for the alerting of low-level windshear it may be advantageous to consider both the larger scale windshear ramps and the smaller scale wind changes, i.e. headwind gradients. This paper examines the usefulness of such an approach by applying the method to the windshear cases in spring time over four years. It turns out that the inclusion of headwind gradients helps capture 5-10 % more of the significant windshear reported by the pilots. For a particular runway corridor, the combined use of the two windshear detection methods even outperforms the existing windshear alerting service at HKIA. The paper will discuss the rationale behind the headwind gradient method, a prototype of its implementation, and its combined use with the existing LIWAS alerts. It will also discuss preliminary results on the climatology of headwind changes at HKIA based on LIDAR data, as well as the use of aircraft simulator in improving the calculation of LIDAR-based F-factor. (orig.)

Sustainable development based energy policy making frameworks, a critical review

International Nuclear Information System (INIS)

Meyar-Naimi, H.; Vaez-Zadeh, S.

2012-01-01

This paper, in the first step, presents an overview of the origination and formulation of sustainable development (SD) concept and the related policy making frameworks. The frameworks include Pressure–State–Response (PSR), Driving Force–State–Response (DSR), Driving Force–Pressure–State–Impact–Response (DPSIR), Driving Force–Pressure–State–Effect–Action (DPSEA) and Driving Force-Pressure-State-Exposure-Effect-Action (DPSEEA). In this regard, 40 case studies using the reviewed frameworks reported during 1994–2011 are surveyed. Then, their application area and application intensity are investigated. It is concluded that PSR, and DPSEA and DPSEEA have the higher and lower application intensities, respectively. Moreover, using Analytical Hierarchy Process (AHP) with a set of criteria, it is shown that PSR and DPSIR have the highest and lowest priorities. Finally, the shortcomings of frameworks applications are discussed. The paper is helpful in selecting appropriate policy making frameworks and presents some hints for future research in the area for developing more comprehensive models especially for sustainable electric energy policy making. - Highlights: ► The origination and formulation of sustainable development (SD) concept is reviewed. ► SD based frameworks (PSR, DSR, DPSIR, DPSEA and DPSEEA) are also reviewed. ► Then, the frameworks application area and intensity in recent years are investigated. ► Finally, the SD concept and the SD based frameworks are criticized. ► It will be helpful for developing more comprehensive energy policy making models.

Filtering Airborne LIDAR Data by AN Improved Morphological Method Based on Multi-Gradient Analysis

Science.gov (United States)

Li, Y.

2013-05-01

The technology of airborne Light Detection And Ranging (LIDAR) is capable of acquiring dense and accurate 3D geospatial data. Although many related efforts have been made by a lot of researchers in the last few years, LIDAR data filtering is still a challenging task, especially for area with high relief or hybrid geographic features. In order to address the bare-ground extraction from LIDAR point clouds of complex landscapes, a novel morphological filtering algorithm is proposed based on multi-gradient analysis in terms of the characteristic of LIDAR data distribution in this paper. Firstly, point clouds are organized by an index mesh. Then, the multigradient of each point is calculated using the morphological method. And, objects are removed gradually by choosing some points to carry on an improved opening operation constrained by multi-gradient iteratively. 15 sample data provided by ISPRS Working Group III/3 are employed to test the filtering algorithm proposed. These sample data include those environments that may lead to filtering difficulty. Experimental results show that filtering algorithm proposed by this paper is of high adaptability to various scenes including urban and rural areas. Omission error, commission error and total error can be simultaneously controlled in a relatively small interval. This algorithm can efficiently remove object points while preserves ground points to a great degree.

Base Stock Policy in a Join-Type Production Line with Advanced Demand Information

Science.gov (United States)

Hiraiwa, Mikihiko; Tsubouchi, Satoshi; Nakade, Koichi

Production control such as the base stock policy, the kanban policy and the constant work-in-process policy in a serial production line has been studied by many researchers. Production lines, however, usually have fork-type, join-type or network-type figures. In addition, in most previous studies on production control, a finished product is required at the same time as arrival of demand at the system. Demand information is, however, informed before due date in practice. In this paper a join-type (assembly) production line under base stock control with advanced demand information in discrete time is analyzed. The recursive equations for the work-in-process are derived. The heuristic algorithm for finding appropriate base stock levels of all machines at short time is proposed and the effect of advanced demand information is examined by simulation with the proposed algorithm. It is shown that the inventory cost can decreases with little backlogs by using the appropriate amount of demand information and setting appropriate base stock levels.

Strength gradient enhances fatigue resistance of steels

Science.gov (United States)

Ma, Zhiwei; Liu, Jiabin; Wang, Gang; Wang, Hongtao; Wei, Yujie; Gao, Huajian

2016-02-01

Steels are heavily used in infrastructure and the transportation industry, and enhancing their fatigue resistance is a major challenge in materials engineering. In this study, by introducing a gradient microstructure into 304 austenitic steel, which is one of the most widely used types of stainless steel, we show that a strength gradient substantially enhances the fatigue life of the material. Pre-notched samples with negative strength gradients in front of the notch’s tip endure many more fatigue cycles than do samples with positive strength gradients during the crack initiation stage, and samples with either type of gradient perform better than do gradient-free samples with the same average yield strength. However, as a crack grows, samples with positive strength gradients exhibit better resistance to fatigue crack propagation than do samples with negative gradients or no gradient. This study demonstrates a simple and promising strategy for using gradient structures to enhance the fatigue resistance of materials and complements related studies of strength and ductility.

Micro-Structural Evolution and Size-Effects in Plastically Deformed Single Crystals: Strain Gradient Continuum Modeling

DEFF Research Database (Denmark)

El-Naaman, Salim Abdallah

the macroscopic effects related to strain gradients, most predict smooth micro-structures. The evolution of dislocation micro-structures, during plastic straining of ductile crystalline materials, is highly complex and nonuniform. Published experimental measurements on deformed metal crystals show distinct......An extensive amount of research has been devoted to the development of micro-mechanics based gradient plasticity continuum theories, which are necessary for modeling micron-scale plasticity when large spatial gradients of plastic strain appear. While many models have proven successful in capturing...... strain. It is clear that many challenges are associated with modeling dislocation structures, within a framework based on continuum fields, however, since the strain gradient effects are attributed to the dislocation micro-structure, it is a natural step, in the further development of gradient theories...

Trends in the educational gradient of mortality among US adults aged 45 to 84 years: bringing regional context into the explanation.

Science.gov (United States)

Montez, Jennifer Karas; Berkman, Lisa F

2014-01-01

We investigated trends in the educational gradient of US adult mortality, which has increased at the national level since the mid-1980s, within US regions. We used data from the 1986-2006 National Health Interview Survey Linked Mortality File on non-Hispanic White and Black adults aged 45 to 84 years (n = 498,517). We examined trends in the gradient within 4 US regions by race-gender subgroup by using age-standardized death rates. Trends in the gradient exhibited a few subtle regional differences. Among women, the gradient was often narrowest in the Northeast. The region's distinction grew over time mainly because low-educated women in the Northeast did not experience a significant increase in mortality like their counterparts in other regions (particularly for White women). Among White men, the gradient narrowed to a small degree in the West. The subtle regional differences indicate that geographic context can accentuate or suppress trends in the gradient. Studies of smaller areas may provide insights into the specific contextual characteristics (e.g., state tax policies) that have shaped the trends, and thus help explain and reverse the widening mortality disparities among US adults.

Gradient Boosting Machines, A Tutorial

Directory of Open Access Journals (Sweden)

Alexey eNatekin

2013-12-01

Full Text Available Gradient boosting machines are a family of powerful machine-learning techniques that have shown considerable success in a wide range of practical applications. They are highly customizable to the particular needs of the application, like being learned with respect to different loss functions. This article gives a tutorial introduction into the methodology of gradient boosting methods. A theoretical information is complemented with many descriptive examples and illustrations which cover all the stages of the gradient boosting model design. Considerations on handling the model complexity are discussed. A set of practical examples of gradient boosting applications are presented and comprehensively analyzed.

The geomagnetic field gradient tensor

DEFF Research Database (Denmark)

Kotsiaros, Stavros; Olsen, Nils

2012-01-01

We develop the general mathematical basis for space magnetic gradiometry in spherical coordinates. The magnetic gradient tensor is a second rank tensor consisting of 3 × 3 = 9 spatial derivatives. Since the geomagnetic field vector B is always solenoidal (∇ · B = 0) there are only eight independent...... tensor elements. Furthermore, in current free regions the magnetic gradient tensor becomes symmetric, further reducing the number of independent elements to five. In that case B is a Laplacian potential field and the gradient tensor can be expressed in series of spherical harmonics. We present properties...... of the magnetic gradient tensor and provide explicit expressions of its elements in terms of spherical harmonics. Finally we discuss the benefit of using gradient measurements for exploring the Earth’s magnetic field from space, in particular the advantage of the various tensor elements for a better determination...

An online supervised learning method based on gradient descent for spiking neurons.

Science.gov (United States)

Xu, Yan; Yang, Jing; Zhong, Shuiming

2017-09-01

The purpose of supervised learning with temporal encoding for spiking neurons is to make the neurons emit a specific spike train encoded by precise firing times of spikes. The gradient-descent-based (GDB) learning methods are widely used and verified in the current research. Although the existing GDB multi-spike learning (or spike sequence learning) methods have good performance, they work in an offline manner and still have some limitations. This paper proposes an online GDB spike sequence learning method for spiking neurons that is based on the online adjustment mechanism of real biological neuron synapses. The method constructs error function and calculates the adjustment of synaptic weights as soon as the neurons emit a spike during their running process. We analyze and synthesize desired and actual output spikes to select appropriate input spikes in the calculation of weight adjustment in this paper. The experimental results show that our method obviously improves learning performance compared with the offline learning manner and has certain advantage on learning accuracy compared with other learning methods. Stronger learning ability determines that the method has large pattern storage capacity. Copyright © 2017 Elsevier Ltd. All rights reserved.

Performance evaluation of matrix gradient coils.

Science.gov (United States)

Jia, Feng; Schultz, Gerrit; Testud, Frederik; Welz, Anna Masako; Weber, Hans; Littin, Sebastian; Yu, Huijun; Hennig, Jürgen; Zaitsev, Maxim

2016-02-01

In this paper, we present a new performance measure of a matrix coil (also known as multi-coil) from the perspective of efficient, local, non-linear encoding without explicitly considering target encoding fields. An optimization problem based on a joint optimization for the non-linear encoding fields is formulated. Based on the derived objective function, a figure of merit of a matrix coil is defined, which is a generalization of a previously known resistive figure of merit for traditional gradient coils. A cylindrical matrix coil design with a high number of elements is used to illustrate the proposed performance measure. The results are analyzed to reveal novel features of matrix coil designs, which allowed us to optimize coil parameters, such as number of coil elements. A comparison to a scaled, existing multi-coil is also provided to demonstrate the use of the proposed performance parameter. The assessment of a matrix gradient coil profits from using a single performance parameter that takes the local encoding performance of the coil into account in relation to the dissipated power.

New Conjugacy Conditions and Related Nonlinear Conjugate Gradient Methods

International Nuclear Information System (INIS)

Dai, Y.-H.; Liao, L.-Z.

2001-01-01

Conjugate gradient methods are a class of important methods for unconstrained optimization, especially when the dimension is large. This paper proposes a new conjugacy condition, which considers an inexact line search scheme but reduces to the old one if the line search is exact. Based on the new conjugacy condition, two nonlinear conjugate gradient methods are constructed. Convergence analysis for the two methods is provided. Our numerical results show that one of the methods is very efficient for the given test problems

Gradient-driven flux-tube simulations of ion temperature gradient turbulence close to the non-linear threshold

Energy Technology Data Exchange (ETDEWEB)

Peeters, A. G.; Rath, F.; Buchholz, R.; Grosshauser, S. R.; Strintzi, D.; Weikl, A. [Physics Department, University of Bayreuth, Universitätsstrasse 30, Bayreuth (Germany); Camenen, Y. [Aix Marseille Univ, CNRS, PIIM, UMR 7345, Marseille (France); Candy, J. [General Atomics, PO Box 85608, San Diego, California 92186-5608 (United States); Casson, F. J. [CCFE, Culham Science Centre, Abingdon OX14 3DB, Oxon (United Kingdom); Hornsby, W. A. [Max Planck Institut für Plasmaphysik, Boltzmannstrasse 2 85748 Garching (Germany)

2016-08-15

It is shown that Ion Temperature Gradient turbulence close to the threshold exhibits a long time behaviour, with smaller heat fluxes at later times. This reduction is connected with the slow growth of long wave length zonal flows, and consequently, the numerical dissipation on these flows must be sufficiently small. Close to the nonlinear threshold for turbulence generation, a relatively small dissipation can maintain a turbulent state with a sizeable heat flux, through the damping of the zonal flow. Lowering the dissipation causes the turbulence, for temperature gradients close to the threshold, to be subdued. The heat flux then does not go smoothly to zero when the threshold is approached from above. Rather, a finite minimum heat flux is obtained below which no fully developed turbulent state exists. The threshold value of the temperature gradient length at which this finite heat flux is obtained is up to 30% larger compared with the threshold value obtained by extrapolating the heat flux to zero, and the cyclone base case is found to be nonlinearly stable. Transport is subdued when a fully developed staircase structure in the E × B shearing rate forms. Just above the threshold, an incomplete staircase develops, and transport is mediated by avalanche structures which propagate through the marginally stable regions.

Designing and implementing science-based methane policies

Science.gov (United States)

George, F.

2017-12-01

The phenomenal growth in shale gas production across the U.S. has significantly improved the energy security and economic prospects of the country. Natural gas is a "versatile" fuel that has application in every major end-use sector of the economy, both as a fuel and a feedstock. Natural gas has also played a significant role in reducing CO2 emissions from the power sector by displacing more carbon intensive fossil fuels. However, emissions of natural gas (predominantly methane) from the wellhead to the burner tip can erode this environmental benefit. Preserving the many benefits of America's natural gas resources requires smart, science-based policies to optimize the energy delivery efficiency of the natural gas supply chain and ensure that natural gas remains a key pillar in our transition to a low-carbon economy. Southwestern Energy (SWN) is the third largest natural gas producer in the United States. Over the last several years, SWN has participated in a number of scientific studies with regulatory agencies, academia and non-governmental entities that have led to over a dozen peer-reviewed papers on methane emissions from oil and gas operations. This presentation will review how our participation in these studies has informed our internal policies and procedures, as well as our external programs, including the ONE Future coalition (ONE Future). In particular, the presentation will highlight the impact of such studies on our Leak Detection and Repair (LDAR) program, designing new methane research and on the ONE Future initiatives - all with the focus of improving the delivery efficiency of oil and gas operations. Our experience supports continued research in the detection and mitigation of methane emissions, with emphasis on longer duration characterization of methane emissions from oil and gas facilities and further development of cost-effective methane detection and mitigation techniques. We conclude from our scientific and operational experiences that a

PROSPECTS OF THE REGIONAL INTEGRATION POLICY BASED ON CLUSTER FORMATION

Directory of Open Access Journals (Sweden)

Elena Tsepilova

2018-01-01

Full Text Available The purpose of this article is to develop the theoretical foundations of regional integration policy and to determine its prospects on the basis of cluster formation. The authors use such research methods as systematization, comparative and complex analysis, synthesis, statistical method. Within the framework of the research, the concept of regional integration policy is specified, and its integration core – cluster – is allocated. The authors work out an algorithm of regional clustering, which will ensure the growth of economy and tax income. Measures have been proposed to optimize the organizational mechanism of interaction between the participants of the territorial cluster and the authorities that allow to ensure the effective functioning of clusters, including taxation clusters. Based on the results of studying the existing methods for assessing the effectiveness of cluster policy, the authors propose their own approach to evaluating the consequences of implementing the regional integration policy, according to which the list of quantitative and qualitative indicators is defined. The present article systematizes the experience and results of the cluster policy of certain European countries, that made it possible to determine the prospects and synergetic effect from the development of clusters as an integration foundation of regional policy in the Russian Federation. The authors carry out the analysis of activity of cluster formations using the example of the Rostov region – a leader in the formation of conditions for the cluster policy development in the Southern Federal District. 11 clusters and cluster initiatives are developing in this region. As a result, the authors propose measures for support of the already existing clusters and creation of the new ones.

Electrical Field Guided Electrospray Deposition for Production of Gradient Particle Patterns.

Science.gov (United States)

Yan, Wei-Cheng; Xie, Jingwei; Wang, Chi-Hwa

2018-06-06

Our previous work demonstrated the uniform particle pattern formation on the substrates using electrical field guided electrospray deposition. In this work, we reported for the first time the fabrication of gradient particle patterns on glass slides using an additional point, line, or bar electrode based on our previous electrospray deposition configuration. We also demonstrated that the polydimethylsiloxane (PDMS) coating could result in the formation of uniform particle patterns instead of gradient particle patterns on glass slides using the same experimental setup. Meanwhile, we investigated the effect of experimental configurations on the gradient particle pattern formation by computational simulation. The simulation results are in line with experimental observations. The formation of gradient particle patterns was ascribed to the gradient of electric field and the corresponding focusing effect. Cell patterns can be formed on the particle patterns deposited on PDMS-coated glass slides. The formed particle patterns hold great promise for high-throughput screening of biomaterial-cell interactions and sensing.

Evidence-based policymaking is not like evidence-based medicine, so how far should you go to bridge the divide between evidence and policy?

Science.gov (United States)

Cairney, Paul; Oliver, Kathryn

2017-04-26

There is extensive health and public health literature on the 'evidence-policy gap', exploring the frustrating experiences of scientists trying to secure a response to the problems and solutions they raise and identifying the need for better evidence to reduce policymaker uncertainty. We offer a new perspective by using policy theory to propose research with greater impact, identifying the need to use persuasion to reduce ambiguity, and to adapt to multi-level policymaking systems.We identify insights from secondary data, namely systematic reviews, critical analysis and policy theories relevant to evidence-based policymaking. The studies are drawn primarily from countries such as the United States, United Kingdom, Canada, Australia and New Zealand. We combine empirical and normative elements to identify the ways in which scientists can, do and could influence policy.We identify two important dilemmas, for scientists and researchers, that arise from our initial advice. First, effective actors combine evidence with manipulative emotional appeals to influence the policy agenda - should scientists do the same, or would the reputational costs outweigh the policy benefits? Second, when adapting to multi-level policymaking, should scientists prioritise 'evidence-based' policymaking above other factors? The latter includes governance principles such the 'co-production' of policy between local public bodies, interest groups and service users. This process may be based primarily on values and involve actors with no commitment to a hierarchy of evidence.We conclude that successful engagement in 'evidence-based policymaking' requires pragmatism, combining scientific evidence with governance principles, and persuasion to translate complex evidence into simple stories. To maximise the use of scientific evidence in health and public health policy, researchers should recognise the tendency of policymakers to base judgements on their beliefs, and shortcuts based on their emotions

Management of clandestine drug laboratories: need for evidence-based environmental health policies.

Science.gov (United States)

Al-Obaidi, Tamara A; Fletcher, Stephanie M

2014-01-01

Clandestine drug laboratories (CDLs) have been emerging and increasing as a public health problem in Australia, with methamphetamine being the dominant illegally manufactured drug. However, management and remediation of contaminated properties are still limited in terms of regulation and direction, especially in relation to public and environmental health practice. Therefore, this review provides an update on the hazards and health effects associated with CDLs, with a specific look at the management of these labs from an Australian perspective. Particularly, the paper attempts to describe the policy landscape for management of CDLs, and identifies current gaps and how further research may be utilised to advance understanding and management of CDLs and inform public health policies. The paper highlights a significant lack of evidence-based policies and guidelines to guide regulatory authority including environmental health officers in Australia. Only recently, the national Clandestine Drug Laboratory Guidelines were developed to assist relevant authority and specialists manage and carry out investigations and remediation of contaminated sites. However, only three states have developed state-based guidelines, some of which are inadequate to meet environmental health requirements. The review recommends well-needed inter-sectoral collaborations and further research to provide an evidence base for the development of robust policies and standard operating procedures for safe and effective environmental health management and remediation of CDLs.

Evidence-based ICT Policy for Development and Innovation | CRDI ...

International Development Research Centre (IDRC) Digital Library (Canada)

Evidence-based ICT Policy for Development and Innovation. The cost of access to information and communication technologies (ITCs) in Africa remains the major impediment to the participation of Africans in the networked society. While Africa is the region with the fastest growing number of mobile phone subscribers in the ...

The evolution of conditional dispersal and reproductive isolation along environmental gradients.

Science.gov (United States)

Payne, Joshua L; Mazzucco, Rupert; Dieckmann, Ulf

2011-03-21

Dispersal modulates gene flow throughout a population's spatial range. Gene flow affects adaptation at local spatial scales, and consequently impacts the evolution of reproductive isolation. A recent theoretical investigation has demonstrated that local adaptation along an environmental gradient, facilitated by the evolution of limited dispersal, can lead to parapatric speciation even in the absence of assortative mating. This and other studies assumed unconditional dispersal, so individuals start dispersing without regard to local environmental conditions. However, many species disperse conditionally; their propensity to disperse is contingent upon environmental cues, such as the degree of local crowding or the availability of suitable mates. Here, we use an individual-based model in continuous space to investigate by numerical simulation the relationship between the evolution of threshold-based conditional dispersal and parapatric speciation driven by frequency-dependent competition along environmental gradients. We find that, as with unconditional dispersal, parapatric speciation occurs under a broad range of conditions when reproduction is asexual, and under a more restricted range of conditions when reproduction is sexual. In both the asexual and sexual cases, the evolution of conditional dispersal is strongly influenced by the slope of the environmental gradient: shallow environmental gradients result in low dispersal thresholds and high dispersal distances, while steep environmental gradients result in high dispersal thresholds and low dispersal distances. The latter, however, remain higher than under unconditional dispersal, thus undermining isolation by distance, and hindering speciation in sexual populations. Consequently, the speciation of sexual populations under conditional dispersal is triggered by a steeper gradient than under unconditional dispersal. Enhancing the disruptiveness of frequency-dependent selection, more box-shaped competition kernels

Mutation screening of the TP53 gene by temporal temperature gradient gel electrophoresis.

Science.gov (United States)

Sørlie, Therese; Johnsen, Hilde; Vu, Phuong; Lind, Guro Elisabeth; Lothe, Ragnhild; Børresen-Dale, Anne-Lise

2005-01-01

A protocol for detection of mutations in the TP53 gene using temporal temperature gradient gel electrophoresis (TTGE) is described. TTGE is a mutation detection technique that separates DNA fragments differing by single base pairs according to their melting properties in a denaturing gel. It is based on constant denaturing conditions in the gel combined with a temperature gradient during the electrophoretic run. This method combines some of the advantages of the related techniques denaturing gradient gel electrophoresis (DGGE) and constant denaturant gel electrophoresis (CDGE) and eliminates some of the problems. The result is a rapid and sensitive screening technique that is robust and easily set up in smaller laboratory environments.

Spatial Resolution Effect on Forest Road Gradient Calculation and Erosion Modelling

Science.gov (United States)

Cao, L.; Elliot, W.

2017-12-01

, predicted erosion rates exponentially increased with segment length. At the watershed scale, most of the predicted soil loss occurred on segments with gradients ranging from 3% to 9%. Based on the road gradient calculated with the 10-m and 30-m DEMs, soil loss was overestimated when compared to the 1m LiDAR DEM. Both the 10m and 30m DEM result in similar total road soil loss.

Generating multiplex gradients of biomolecules for controlling cellular adhesion in parallel microfluidic channels.

Science.gov (United States)

Didar, Tohid Fatanat; Tabrizian, Maryam

2012-11-07

Here we present a microfluidic platform to generate multiplex gradients of biomolecules within parallel microfluidic channels, in which a range of multiplex concentration gradients with different profile shapes are simultaneously produced. Nonlinear polynomial gradients were also generated using this device. The gradient generation principle is based on implementing parrallel channels with each providing a different hydrodynamic resistance. The generated biomolecule gradients were then covalently functionalized onto the microchannel surfaces. Surface gradients along the channel width were a result of covalent attachments of biomolecules to the surface, which remained functional under high shear stresses (50 dyn/cm(2)). An IgG antibody conjugated to three different fluorescence dyes (FITC, Cy5 and Cy3) was used to demonstrate the resulting multiplex concentration gradients of biomolecules. The device enabled generation of gradients with up to three different biomolecules in each channel with varying concentration profiles. We were also able to produce 2-dimensional gradients in which biomolecules were distributed along the length and width of the channel. To demonstrate the applicability of the developed design, three different multiplex concentration gradients of REDV and KRSR peptides were patterned along the width of three parallel channels and adhesion of primary human umbilical vein endothelial cell (HUVEC) in each channel was subsequently investigated using a single chip.

Block-conjugate-gradient method

International Nuclear Information System (INIS)

McCarthy, J.F.

1989-01-01

It is shown that by using the block-conjugate-gradient method several, say s, columns of the inverse Kogut-Susskind fermion matrix can be found simultaneously, in less time than it would take to run the standard conjugate-gradient algorithm s times. The method improves in efficiency relative to the standard conjugate-gradient algorithm as the fermion mass is decreased and as the value of the coupling is pushed to its limit before the finite-size effects become important. Thus it is potentially useful for measuring propagators in large lattice-gauge-theory calculations of the particle spectrum

Gradient-index phononic crystal lens-based enhancement of elastic wave energy harvesting

Science.gov (United States)

Tol, S.; Degertekin, F. L.; Erturk, A.

2016-08-01

We explore the enhancement of structure-borne elastic wave energy harvesting, both numerically and experimentally, by exploiting a Gradient-Index Phononic Crystal Lens (GRIN-PCL) structure. The proposed GRIN-PCL is formed by an array of blind holes with different diameters on an aluminum plate, where the blind hole distribution is tailored to obtain a hyperbolic secant gradient profile of refractive index guided by finite-element simulations of the lowest asymmetric mode Lamb wave band diagrams. Under plane wave excitation from a line source, experimentally measured wave field validates the numerical simulation of wave focusing within the GRIN-PCL domain. A piezoelectric energy harvester disk located at the first focus of the GRIN-PCL yields an order of magnitude larger power output as compared to the baseline case of energy harvesting without the GRIN-PCL on the uniform plate counterpart.

Air temperature gradient in large industrial hall

Science.gov (United States)

Karpuk, Michał; Pełech, Aleksander; Przydróżny, Edward; Walaszczyk, Juliusz; Szczęśniak, Sylwia

2017-11-01

In the rooms with dominant sensible heat load, volume airflow depends on many factors incl. pre-established temperature difference between exhaust and supply airflow. As the temperature difference is getting higher, airflow volume drops down, consequently, the cost of AHU is reduced. In high industrial halls with air exhaust grids located under the ceiling additional temperature gradient above working zone should be taken into consideration. In this regard, experimental research of the vertical air temperature gradient in high industrial halls were carried out for the case of mixing ventilation system The paper presents the results of air temperature distribution measurements in high technological hall (mechanically ventilated) under significant sensible heat load conditions. The supply airflow was delivered to the hall with the help of the swirl diffusers while exhaust grids were located under the hall ceiling. Basing on the air temperature distribution measurements performed on the seven pre-established levels, air temperature gradient in the area between 2.0 and 7.0 m above the floor was calculated and analysed.

Economic gradients in early child neurodevelopment: A multi-country study

Science.gov (United States)

Wehby, George L.; McCarthy, Ann Marie

2013-01-01

Little is known about the importance of household wealth for child neurodevelopment very early in life including during infancy. Previous studies have focused on specific developmental domains instead of more holistic multi-domain measures of neurodevelopment and on economic effects for the “average” child instead of evaluating the heterogeneity in economic gradients by different levels of developmental ability. Furthermore, not much is known about whether economic gradients in early child neurodevelopment are country-specific or generalizable between populations. We evaluate wealth gradients in child neurodevelopment, an important predictor of future health and human capital, between ages 3 and 24 months in four South American countries. We also assess the heterogeneity in these gradients at different locations of the neurodevelopment distribution using quantile regression. Employing a unique dataset of 2032 children with neurodevelopment measures obtained by physicians in 2005–2006, we find a large positive wealth gradient in neurodevelopment in Brazil. The wealth gradient is larger for children at higher neurodevelopment rankings, suggesting that wealth is associated with child development inequalities in the form of a wider gap between low and high achievers on neurodevelopment in Brazil. This result highlights the need to target poverty in Brazil as a key factor in health and human capital disparities earlier in life rather than later as early developmental deficits will be carried forward and possibly multiplied later in life. More importantly, small or insignificant wealth gradients are generally found in the other countries. These results suggest that wealth gradients in child neurodevelopment are country-specific and vary with population demographic, health, and socioeconomic characteristics. Therefore, findings from previous studies based on specific populations may not be generalizable to other countries. Furthermore, wealth gradients in child

СREATING OF BARCODES FOR FACIAL IMAGES BASED ON INTENSITY GRADIENTS

Directory of Open Access Journals (Sweden)

G. A. Kukharev

2014-05-01

Full Text Available The paper provides analysis of existing approaches to the generating of barcodes and description of the system structure for generating of barcodes from facial images. The method for generating of standard type linear barcodes from facial images is proposed. This method is based on the difference of intensity gradients, which represent images in the form of initial features. Further averaging of these features into a limited number of intervals is performed; the quantization of results into decimal digits from 0 to 9 and table conversion into the standard barcode is done. Testing was conducted on the Face94 database and database of composite faces of different ages. It showed that the proposed method ensures the stability of generated barcodes according to changes of scale, pose and mirroring of facial images, as well as changes of facial expressions and shadows on faces from local lighting. The proposed solutions are computationally low-cost and do not require the use of any specialized image processing software for generating of facial barcodes in real-time systems.

Strain gradient drives shear banding in metallic glasses

Science.gov (United States)

Tian, Zhi-Li; Wang, Yun-Jiang; Chen, Yan; Dai, Lan-Hong

2017-09-01

Shear banding is a nucleation-controlled process in metallic glasses (MGs) involving multiple temporal-spatial scales, which hinders a concrete understanding of its structural origin down to the atomic scale. Here, inspired by the morphology of composite materials, we propose a different perspective of MGs as a hard particle-reinforced material based on atomic-scale structural heterogeneity. The local stable structures indicated by a high level of local fivefold symmetry (L5FS) act as hard "particles" which are embedded in the relatively soft matrix. We demonstrate this concept by performing atomistic simulations of shear banding in CuZr MG. A shear band is prone to form in a sample with a high degree of L5FS which is slowly quenched from the liquid. An atomic-scale analysis on strain and the structural evolution reveals that it is the strain gradient effect that has originated from structural heterogeneity that facilitates shear transformation zones (STZs) to mature shear bands. An artificial composite model with a high degree of strain gradient, generated by inserting hard MG strips into a soft MG matrix, demonstrates a great propensity for shear banding. It therefore confirms the critical role strain gradient plays in shear banding. The strain gradient effect on shear banding is further quantified with a continuum model and a mechanical instability analysis. These physical insights might highlight the strain gradient as the hidden driving force in transforming STZs into shear bands in MGs.

Food Availability in School Stores in Seoul, South Korea after Implementation of Food- and Nutrient-Based Policies

Science.gov (United States)

Choi, Seul Ki; Frongillo, Edward A.; Blake, Christine E.; Thrasher, James F.

2017-01-01

Background: To improve school store food environments, the South Korean government implemented 2 policies restricting unhealthy food sales in school stores. A food-based policy enacted in 2007 restricts specific food sales (soft drinks); and a nutrient-based policy enacted in 2009 restricts energy-dense and nutrient-poor (EDNP) food sales. The…

Corporate Language Policies

DEFF Research Database (Denmark)

Sanden, Guro Refsum

This paper offers a review of literature dealing with language policies in general and corporate language policies in particular. Based on a discussion of various definitions of these concepts within two research traditions, i.e. sociolinguistics and international management, a three......-level definition of corporate language policies is presented, emphasising that a corporate language policy is a context-specific policy about language use. The three-level definition is based on the argument that in order to acquire a complete understanding of what corporate language policies involve, one needs...... to consider three progressive questions; 1) what is a policy? 2) what is a language policy?, and ultimately, 3) what is a corporate language policy?...

Corporate Language Policies

DEFF Research Database (Denmark)

Sanden, Guro Refsum

2015-01-01

This paper offers a review of literature dealing with language policies in general and corporate language policies in particular. Based on a discussion of various definitions of these concepts within two research traditions, i.e. sociolinguistics and international management, a three......-level definition of corporate language policies is presented, emphasising that a corporate language policy is a context-specific policy about language use. The three-level definition is based on the argument that in order to acquire a complete understanding of what corporate language policies involve, one needs...... to consider three progressive questions; 1) what is a policy? 2) what is a language policy?, and ultimately, 3) what is a corporate language policy?...

3D DC Resistivity Inversion with Topography Based on Regularized Conjugate Gradient Method

Directory of Open Access Journals (Sweden)

Jian-ke Qiang

2013-01-01

Full Text Available During the past decades, we observed a strong interest in 3D DC resistivity inversion and imaging with complex topography. In this paper, we implemented 3D DC resistivity inversion based on regularized conjugate gradient method with FEM. The Fréchet derivative is assembled with the electric potential in order to speed up the inversion process based on the reciprocity theorem. In this study, we also analyzed the sensitivity of the electric potential on the earth’s surface to the conductivity in each cell underground and introduced an optimized weighting function to produce new sensitivity matrix. The synthetic model study shows that this optimized weighting function is helpful to improve the resolution of deep anomaly. By incorporating topography into inversion, the artificial anomaly which is actually caused by topography can be eliminated. As a result, this algorithm potentially can be applied to process the DC resistivity data collected in mountain area. Our synthetic model study also shows that the convergence and computation speed are very stable and fast.

Full waveform inversion based on the optimized gradient and its spectral implementation

KAUST Repository

Wu, Zedong; Alkhalifah, Tariq Ali

2014-01-01

for the convergence are available, the high number of iterations required to approach a solution renders FWI as very expensive (especially in 3D). A spectral implementation in which the wavefields are extrapolated and gradients are calculated in the wavenumber domain

Improving anti-bullying laws and policies to protect youth from weight-based victimization: parental support for action.

Science.gov (United States)

Puhl, R M; Suh, Y; Li, X

2017-04-01

Weight-based bullying is a prevalent problem among youth with overweight and obesity, but remains neglected in existing policy-level strategies to address youth bullying. Parental support is an influential catalyst motivating political will for policy decisions affecting youth, but has received limited research attention. To assess levels of, and predictors of, parental support for school-based policies and state/federal legal measures to address weight-based bullying in 2014 and 2015. Identical online questionnaires were completed by two independent national samples of parents in 2014 and 2015 (N = 1804). Parental support for all policy actions was high (at least 81%) and significantly increased from 2014 to 2015 for legal measures that would a) require state anti-bullying laws to add protections against weight-based bullying, and b) enact a federal anti-bullying law that includes weight-based bullying. These findings can inform policy discourse about remedies for youth bullying, and suggest that parental support for improved legal protections against weight-based bullying is present, consistent, and strong. © 2016 World Obesity Federation.

Study of flow instability in a centrifugal fan based on energy gradient theory

International Nuclear Information System (INIS)

Xiao, Meina; Dou, Hua-Shu; Ma, Xiaoyang; Xiao, Qing; Chen, Yongning; He, Haijiang; Ye, Xinxue

2016-01-01

Flow instability in a centrifugal fan was studied using energy gradient theory. Numerical simulation was performed for the three dimensional turbulent flow field in a centrifugal fan. The flow is governed by the three-dimensional incompressible Navier-Stokes equations coupled with the RNG k-ε turbulent model. The finite volume method was used to discretize the governing equations and the Semiimplicit method for pressure linked equation (SIMPLE) algorithm is employed to iterate the system of the equations. The interior flow field in the centrifugal fan and the distribution of the energy gradient function K are obtained at different flow rates. According to the energy gradient method, the area with larger value of K is the place where the flow loses stability easier. The results show that instability is easier to generate in the regions of impeller outlet and volute tongue. The air flow near the hub is more stable than that near the shroud. That is due to the influences of variations of the velocity and the inlet angle along the axial direction. With the decrease of the flow rate, instability zone in a blade channel moves to the impeller inlet from the outlet and the unstable regions in different channels develop in opposite direction to the rotation of impeller

Structuring AHP-based maintenance policy selection

NARCIS (Netherlands)

Goossens, Adriaan; Basten, Robertus Johannes Ida; Hummel, J. Marjan; van der Wegen, Leonardus L.M.

2015-01-01

We aim to structure the maintenance policy selection process for ships, using the Analytic Hierarchy Process (AHP). Maintenance is an important contributor to reach the intended life-time of capital technical assets, and it is gaining increasing interest and relevance. A maintenance policy is a

Slab Geometry and Segmentation on Seismogenic Subduction Zone; Insight from gravity gradients

Science.gov (United States)

Saraswati, A. T.; Mazzotti, S.; Cattin, R.; Cadio, C.

2017-12-01

Slab geometry is a key parameter to improve seismic hazard assessment in subduction zones. In many cases, information about structures beneath subduction are obtained from geophysical dedicated studies, including geodetic and seismic measurements. However, due to the lack of global information, both geometry and segmentation in seismogenic zone of many subductions remain badly-constrained. Here we propose an alternative approach based on satellite gravity observations. The GOCE (Gravity field and steady-state Ocean Circulation Explorer) mission enables to probe Earth deep mass structures from gravity gradients, which are more sensitive to spatial structure geometry and directional properties than classical gravitational data. Gravity gradients forward modeling of modeled slab is performed by using horizontal and vertical gravity gradient components to better determine slab geophysical model rather than vertical gradient only. Using polyhedron method, topography correction on gravity gradient signal is undertaken to enhance the anomaly signal of lithospheric structures. Afterward, we compare residual gravity gradients with the calculated signals associated with slab geometry. In this preliminary study, straightforward models are used to better understand the characteristic of gravity gradient signals due to deep mass sources. We pay a special attention to the delineation of slab borders and dip angle variations.

Near field plasmonic gradient effects on high vacuum tip-enhanced Raman spectroscopy.

Science.gov (United States)

Fang, Yurui; Zhang, Zhenglong; Chen, Li; Sun, Mengtao

2015-01-14

Near field gradient effects in high vacuum tip-enhanced Raman spectroscopy (HV-TERS) are a recent developing ultra-sensitive optical and spectral analysis technology on the nanoscale, based on the plasmons and plasmonic gradient enhancement in the near field and under high vacuum. HV-TERS can not only be used to detect ultra-sensitive Raman spectra enhanced by surface plasmon, but also to detect clear molecular IR-active modes enhanced by strongly plasmonic gradient. Furthermore, the molecular overtone modes and combinational modes can also be experimentally measured, where the Fermi resonance and Darling-Dennison resonance were successfully observed in HV-TERS. Theoretical calculations using electromagnetic field theory firmly supported experimental observation. The intensity ratio of the plasmon gradient term over the linear plasmon term can reach values greater than 1. Theoretical calculations also revealed that with the increase in gap distance between tip and substrate, the decrease in the plasmon gradient was more significant than the decrease in plasmon intensity, which is the reason that the gradient Raman can be only observed in the near field. Recent experimental results of near field gradient effects on HV-TERS were summarized, following the section of the theoretical analysis.

Informing principal policy reforms in South Africa through data-based evidence

OpenAIRE

Gabrielle Wills

2015-01-01

In the past decade there has been a notable shift in South African education policy that raises the value of school leadership as a lever for learning improvements. Despite a growing discourse on school leadership, there has been a lack of empirical based evidence on principals to inform, validate or debate the efficacy of proposed policies in raising the calibre of school principals. Drawing on findings from a larger study to understand the labour market for school principals in South Africa...

Geothermal gradients map of Hokkaido; Hokkaido no chion kobaizu ni tsuite

Energy Technology Data Exchange (ETDEWEB)

Akita, F.; Matsunami, T.; Wakahama, H. [Hokkaido Geological Survey, Sapporo (Japan)

1997-06-15

This paper outlines the newly prepared geothermal gradient map (GGM) of Hokkaido which is important for survey on geothermal and hot spring resources. The temperature data of 687 wells were compiled by data collection and field survey. The geothermal gradient was calculated from the ratio of the temperature difference between the bottom (deepest well log) and the ground surface (10degC) to a bottom depth. GGM was prepared using data of 85 wells which show real geothermal temperatures through conductive temperature profiles, or SBHT (static bottom hole temperature) calculation is possible. Geological profiles were classified into three types based on base rocks. The thermal structure of GGM was clearly divided into a high geothermal gradient over 10degC/100m, and a low one within 3degC/100m. The former showed active volcano and high geothermal areas, while the latter showed a volcanic front arc area. This underground temperature structure relates to the formation process of volcanos and the origin of magma, and is also similar to the trend of a crust thermal flow rate. The geothermal gradient increases with a decrease in Curie point depth. 26 refs., 10 figs., 2 tabs.

Gradient Alloy for Optical Packaging

Data.gov (United States)

National Aeronautics and Space Administration — Advances in additive manufacturing, such as Laser Engineered Net Shaping (LENS), enables the fabrication of compositionally gradient microstructures, i.e. gradient...

Applications of seismic spatial wavefield gradient and rotation data in exploration seismology

Science.gov (United States)

Schmelzbach, C.; Van Renterghem, C.; Sollberger, D.; Häusler, M.; Robertsson, J. O. A.

2017-12-01

Seismic spatial wavefield gradient and rotation data have the potential to open up new ways to address long-standing problems in land-seismic exploration such as identifying and separating P-, S-, and surface waves. Gradient-based acquisition and processing techniques could enable replacing large arrays of densely spaced receivers by sparse spatially-compact receiver layouts or even one single multicomponent station with dedicated instruments (e.g., rotational seismometers). Such approaches to maximize the information content of single-station recordings are also of significant interest for seismic measurements at sites with limited access such as boreholes, the sea bottom, and extraterrestrial seismology. Arrays of conventional three-component (3C) geophones enable measuring not only the particle velocity in three dimensions but also estimating their spatial gradients. Because the free-surface condition allows to express vertical derivatives in terms of horizontal derivatives, the full gradient tensor and, hence, curl and divergence of the wavefield can be computed. In total, three particle velocity components, three rotational components, and divergence, result seven-component (7C) seismic data. Combined particle velocity and gradient data can be used to isolate the incident P- or S-waves at the land surface or the sea bottom using filtering techniques based on the elastodynamic representation theorem. Alternatively, as only S-waves exhibit rotational motion, rotational measurements can directly be used to identify S-waves. We discuss the derivations of the gradient-based filters as well as their application to synthetic and field data, demonstrating that rotational data can be of particular interest to S-wave reflection and P-to-S-wave conversion imaging. The concept of array-derived gradient estimation can be extended to source arrays as well. Therefore, source arrays allow us to emulate rotational (curl) and dilatational (divergence) sources. Combined with 7C

An equity- and sustainability-based policy response to global climate change

International Nuclear Information System (INIS)

Byrne, J.; Wang, Y.-D.; Kim, Jong-dall

1998-01-01

In the debate over policy options for the reduction of greenhouse gas emissions, two precautionary approaches, 'no regrets' and 'insurance' have been proposed. An alternative to these is put forward which adopts an equity and sustainability based approach. It will not be easy to meet the challenge which this approach demands. From wealthy countries it will require a strong commitment to a social policy at home and an economic policy abroad that aims at sharing the ability of humankind to meet the needs of the present without compromising the ability of future generations to meet their needs. In developing countries the necessary improvement in lives and livelihoods must be achieved without repeating the unsustainable environmental and social legacy of the industrial era. (UK)

When to base clinical policies on observational versus randomized trial data.

Science.gov (United States)

Hornberger, J; Wrone, E

1997-10-15

Physicians must decide when the evidence is sufficient to adopt a new clinical policy. Analysis of large clinical and administrative databases is becoming an important source of evidence for changing clinical policies. Because such analysis cannot control for the effects of all potential confounding variables, physicians risk drawing the wrong conclusion about the cause-and-effect relation between a change in clinical policy and outcomes. Randomized studies offer protection against drawing a conclusion that would lead to adoption of an inferior policy. However, a randomized study may be difficult to justify because of the extra costs of collecting data for a randomized study and concerns that a study will not directly benefit the patients enrolled in the study. This article reviews the advantages and disadvantages of basing clinical policy on analysis of large databases compared with conducting a randomized study. A technique is described and illustrated for accessing the potential costs and benefits of conducting such a study. This type of analysis formed the basis for a physician-managed health care organization deciding to sponsor a randomized study among patients with end-stage renal disease as part of a quality-improvement initiative.

COMPARISON OF GKS CALCULATED CRITICAL ION TEMPERATURE GRADIENTS AND ITG GROWTH RATES TO DIII-D MEASURED GRADIENTS AND DIFFUSIVITIES

International Nuclear Information System (INIS)

BAKER, DR; STAEBLER, GM; PETTY, CC; GREENFIELD, CM; LUCE, TC

2003-01-01

OAK-B135 The gyrokinetic equations predict that various drift type waves or modes can be unstable in a tokamak. For some of these modes, such as the ion temperature gradient (ITG) mode and the electron temperature gradient mode, there exists a critical gradient, above which the mode is unstable. Since the existence of unstable modes can cause increased transport, plasmas which are centrally heated tend to increase in temperature gradient until the modes become unstable. Under some conditions the increased transport can fix the gradient at the critical value. here they present a comparison between the measured ion temperature gradients and the critical gradient as calculated by a gyrokinetic linear stability (GKS) code. They also present the maximum linear growth rate as calculated by this code for comparison to experimentally derived transport coefficients. The results show that for low confinement mode (L-mode) discharges, the measured ion temperature gradient is significantly greater than the GKS calculated critical gradient over a large region of the plasma. This is the same region of the plasma where the ion thermal diffusivity is large. For high confinement mode (H-mode) discharges the ion temperature gradient is closer to the critical gradient, but often still greater than the critical gradient over some region. For the best H-mode discharges, the ion temperature is less than or equal to the critical gradient over the whole plasma. In general they find that the position in the plasma where the ion thermal diffusivity starts to increase rapidly is where the maximum linear growth rate is greater than the E x B shearing rate

Strain gradient effects in surface roughening

DEFF Research Database (Denmark)

Borg, Ulrik; Fleck, N.A.

2007-01-01

evidence for strain gradient effects. Numerical analyses of a bicrystal undergoing in-plane tensile deformation are also studied using a strain gradient crystal plasticity theory and also by using a strain gradient plasticity theory for an isotropic solid. Both theories include an internal material length...

Understanding the cost bases of Space Shuttle pricing policies for commercial and foreign customers

Science.gov (United States)

Stone, Barbara A.

1984-01-01

The principles and underlying cost bases of the 1977 and 1982 Space Shuttle Reimbursement Policies are compared and contrasted. Out-of-pocket cost recovery has been chosen as the base of the price for the 1986-1988 time period. With this cost base, it is NASA's intent to recover the total cost of consumables and the launch and flight operations costs added by commercial and foreign customers over the 1986-1988 time period. Beyond 1988, NASA intends to return to its policy of full cost recovery.

Modified Convolutional Neural Network Based on Dropout and the Stochastic Gradient Descent Optimizer

Directory of Open Access Journals (Sweden)

Jing Yang

2018-03-01

Full Text Available This study proposes a modified convolutional neural network (CNN algorithm that is based on dropout and the stochastic gradient descent (SGD optimizer (MCNN-DS, after analyzing the problems of CNNs in extracting the convolution features, to improve the feature recognition rate and reduce the time-cost of CNNs. The MCNN-DS has a quadratic CNN structure and adopts the rectified linear unit as the activation function to avoid the gradient problem and accelerate convergence. To address the overfitting problem, the algorithm uses an SGD optimizer, which is implemented by inserting a dropout layer into the all-connected and output layers, to minimize cross entropy. This study used the datasets MNIST, HCL2000, and EnglishHand as the benchmark data, analyzed the performance of the SGD optimizer under different learning parameters, and found that the proposed algorithm exhibited good recognition performance when the learning rate was set to [0.05, 0.07]. The performances of WCNN, MLP-CNN, SVM-ELM, and MCNN-DS were compared. Statistical results showed the following: (1 For the benchmark MNIST, the MCNN-DS exhibited a high recognition rate of 99.97%, and the time-cost of the proposed algorithm was merely 21.95% of MLP-CNN, and 10.02% of SVM-ELM; (2 Compared with SVM-ELM, the average improvement in the recognition rate of MCNN-DS was 2.35% for the benchmark HCL2000, and the time-cost of MCNN-DS was only 15.41%; (3 For the EnglishHand test set, the lowest recognition rate of the algorithm was 84.93%, the highest recognition rate was 95.29%, and the average recognition rate was 89.77%.

Education policies and health inequalities: evidence from changes in the distribution of Body Mass Index in France, 1981-2003.

Science.gov (United States)

Etile, Fabrice

2014-03-01

This paper contributes to the debate over the effectiveness of education policies in reducing overall health inequalities as compared to public health actions directed at the less-educated. Recentered Influence Function (RIF) regressions are used to decompose the contribution of education to the changing distribution of Body Mass Index (BMI) in France, between 1981 and 2003, into a composition effect (the shift in population education due to a massive educational expansion), and a structure effect (a changing educational gradient in BMI). Educational expansion has reduced overall BMI inequality by 3.4% for women and 2.3% for men. However, the structure effect on its own has produced a 10.9% increase in overall inequality for women, due to a steeper education gradient starting from the second quartile of the distribution. This structure effect on overall inequality is also large (7.6%) for men, albeit insignificant as it remains concentrated in the last decile. Educational expansion policies can thus reduce overall BMI inequalities; but attention must still be paid to the BMI gradient in education even for policies addressing overall rather than socioeconomic health inequalities. Copyright © 2013 Elsevier B.V. All rights reserved.

Patterns of macromycete community assemblage along an elevation gradient: options for fungal gradient and metacommunity analyse

Science.gov (United States)

Marko Gómez-Hernández; Guadalupe Williams-Linera; Roger Guevara; D. Jean Lodge

2012-01-01

Gradient analysis is rarely used in studies of fungal communities. Data on macromycetes from eight sites along an elevation gradient in central Veracruz, Mexico, were used to demonstrate methods for gradient analysis that can be applied to studies of communities of fungi. Selected sites from 100 to 3,500 m altitude represent tropical dry forest, tropical montane cloud...

LES of the adverse-pressure gradient turbulent boundary layer

International Nuclear Information System (INIS)

Inoue, M.; Pullin, D.I.; Harun, Z.; Marusic, I.

2013-01-01

Highlights: • The adverse-pressure gradient turbulent boundary layer at high Re is studied. • Wall-model LES works well for nonequilibrium turbulent boundary layer. • Relationship of skin-friction to Re and Clauser pressure parameter is explored. • Self-similarity is observed in the velocity statistics over a wide range of Re. -- Abstract: We describe large-eddy simulations (LES) of the flat-plate turbulent boundary layer in the presence of an adverse pressure gradient. The stretched-vortex subgrid-scale model is used in the domain of the flow coupled to a wall model that explicitly accounts for the presence of a finite pressure gradient. The LES are designed to match recent experiments conducted at the University of Melbourne wind tunnel where a plate section with zero pressure gradient is followed by section with constant adverse pressure gradient. First, LES are described at Reynolds numbers based on the local free-stream velocity and the local momentum thickness in the range 6560–13,900 chosen to match the experimental conditions. This is followed by a discussion of further LES at Reynolds numbers at approximately 10 times and 100 times these values, which are well out of range of present day direct numerical simulation and wall-resolved LES. For the lower Reynolds number runs, mean velocity profiles, one-point turbulent statistics of the velocity fluctuations, skin friction and the Clauser and acceleration parameters along the streamwise, adverse pressure-gradient domain are compared to the experimental measurements. For the full range of LES, the relationship of the skin-friction coefficient, in the form of the ratio of the local free-stream velocity to the local friction velocity, to both Reynolds number and the Clauser parameter is explored. At large Reynolds numbers, a region of collapse is found that is well described by a simple log-like empirical relationship over two orders of magnitude. This is expected to be useful for constant adverse

Organizations' Ways of Employing Early Retirees: The Role of Age-Based HR Policies.

Science.gov (United States)

Oude Mulders, Jaap; Henkens, Kène; Schippers, Joop

2015-06-01

We examine whether from an organizational perspective it is possible to distinguish different ways of employing early retirees and explore how the employment of early retirees is related to the application of 4 age-based human resource (HR) policies, namely demotion, offering training opportunities to older workers, offering early retirement, and allowing flexible working hours. We perform a latent class analysis on a sample of 998 Dutch organizations in order to categorize them based on 3 dimensions of their employment of early retirees. We then run a multinomial logistic regression to relate the employment of early retirees to the 4 age-based HR policies. We distinguish 4 types of organizations based on their way of employing early retirees: nonusers (52.6%), users for mainly standard work (20.8%), users for mainly nonstandard work (9.8%), and users for standard and nonstandard work (16.7%). We find that organizations that apply demotion, offer early retirement, and allow flexible working hours are more likely to be users for mainly standard work. Also, organizations that do not offer early retirement are less likely to employ early retirees. Age-based HR policies, especially demotion, offering early retirement, and allowing flexible working hours, are conducive to the employment of early retirees for mainly standard work. Broader implementation of these policies may provide opportunities for older workers to make a more gradual transition from work to retirement. © The Author 2013. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Policy design and performance of emissions trading markets: an adaptive agent-based analysis.

Science.gov (United States)

Bing, Zhang; Qinqin, Yu; Jun, Bi

2010-08-01

Emissions trading is considered to be a cost-effective environmental economic instrument for pollution control. However, the pilot emissions trading programs in China have failed to bring remarkable success in the campaign for pollution control. The policy design of an emissions trading program is found to have a decisive impact on its performance. In this study, an artificial market for sulfur dioxide (SO2) emissions trading applying the agent-based model was constructed. The performance of the Jiangsu SO2 emissions trading market under different policy design scenario was also examined. Results show that the market efficiency of emissions trading is significantly affected by policy design and existing policies. China's coal-electricity price system is the principal factor influencing the performance of the SO2 emissions trading market. Transaction costs would also reduce market efficiency. In addition, current-level emissions discharge fee/tax and banking mechanisms do not distinctly affect policy performance. Thus, applying emissions trading in emission control in China should consider policy design and interaction with other existing policies.

A controlled community-based trial to promote smoke-free policy in rural communities.

Science.gov (United States)

Hahn, Ellen J; Rayens, Mary Kay; Adkins, Sarah; Begley, Kathy; York, Nancy

2015-01-01

Rural, tobacco-growing areas are disproportionately affected by tobacco use, secondhand smoke, and weak tobacco control policies. The purpose was to test the effects of a stage-specific, tailored policy-focused intervention on readiness for smoke-free policy, and policy outcomes in rural underserved communities. A controlled community-based trial including 37 rural counties. Data were collected annually with community advocates (n = 330) and elected officials (n = 158) in 19 intervention counties and 18 comparison counties over 5 years (average response rate = 68%). Intervention communities received policy development strategies from community advisors tailored to their stage of readiness and designed to build capacity, build demand, and translate and disseminate science. Policy outcomes were tracked over 5 years. Communities receiving the stage-specific, tailored intervention had higher overall community readiness scores and better policy outcomes than the comparison counties, controlling for county-level smoking rate, population size, and education. Nearly one-third of the intervention counties adopted smoke-free laws covering restaurants, bars, and all workplaces compared to none of the comparison counties. The stage-specific, tailored policy-focused intervention acted as a value-added resource to local smoke-free campaigns by promoting readiness for policy, as well as actual policy change in rural communities. Although actual policy change and percent covered by the policies were modest, these areas need additional resources and efforts to build capacity, build demand, and translate and disseminate science in order to accelerate smoke-free policy change and reduce the enormous toll from tobacco in these high-risk communities. © 2014 National Rural Health Association.

Combining Correlation-Based and Reward-Based Learning in Neural Control for Policy Improvement

DEFF Research Database (Denmark)

Manoonpong, Poramate; Kolodziejski, Christoph; Wörgötter, Florentin

2013-01-01

Classical conditioning (conventionally modeled as correlation-based learning) and operant conditioning (conventionally modeled as reinforcement learning or reward-based learning) have been found in biological systems. Evidence shows that these two mechanisms strongly involve learning about...... associations. Based on these biological findings, we propose a new learning model to achieve successful control policies for artificial systems. This model combines correlation-based learning using input correlation learning (ICO learning) and reward-based learning using continuous actor–critic reinforcement...... learning (RL), thereby working as a dual learner system. The model performance is evaluated by simulations of a cart-pole system as a dynamic motion control problem and a mobile robot system as a goal-directed behavior control problem. Results show that the model can strongly improve pole balancing control...

Increasing Use of Research Findings in Improving Evidence-Based Health Policy at the National Level

Directory of Open Access Journals (Sweden)

Meiwita Budiharsana

2017-11-01

Full Text Available In February 2016, the Minister of Health decided to increase the use of research findings in improving the quality of the national health policy and planning. The Ministry of Health has instructed the National Institute of Health Research and Development or NIHRD to play a stronger role of monitoring and evaluating all health programs, because “their opinion and research findings should be the basis for changes in national health policies and planning”. Compared to the past, the Ministry of Health has increased the research budget for evidence-based research tremendously. However, there is a gap between the information needs of program and policy-makers and the information offered by researchers. A close dialogue is needed between the users (program managers, policy makers and planners and the suppliers (researchers and evaluators to ensure that the evidence-based supplied by research is useful for programs, planning and health policy.

Weighted graph based ordering techniques for preconditioned conjugate gradient methods

Science.gov (United States)

Clift, Simon S.; Tang, Wei-Pai

1994-01-01

We describe the basis of a matrix ordering heuristic for improving the incomplete factorization used in preconditioned conjugate gradient techniques applied to anisotropic PDE's. Several new matrix ordering techniques, derived from well-known algorithms in combinatorial graph theory, which attempt to implement this heuristic, are described. These ordering techniques are tested against a number of matrices arising from linear anisotropic PDE's, and compared with other matrix ordering techniques. A variation of RCM is shown to generally improve the quality of incomplete factorization preconditioners.

Gradient descent learning in and out of equilibrium

International Nuclear Information System (INIS)

Caticha, Nestor; Araujo de Oliveira, Evaldo

2001-01-01

Relations between the off thermal equilibrium dynamical process of on-line learning and the thermally equilibrated off-line learning are studied for potential gradient descent learning. The approach of Opper to study on-line Bayesian algorithms is used for potential based or maximum likelihood learning. We look at the on-line learning algorithm that best approximates the off-line algorithm in the sense of least Kullback-Leibler information loss. The closest on-line algorithm works by updating the weights along the gradient of an effective potential, which is different from the parent off-line potential. A few examples are analyzed and the origin of the potential annealing is discussed

Improving the evidence base for energy policy: The role of systematic reviews

International Nuclear Information System (INIS)

Sorrell, Steve

2007-01-01

The concept of evidence-based policy and practice (EBPP) has gained increasing prominence in the UK over the last 10 years and now plays a dominant role in a number of policy areas, including healthcare, education, social work, criminal justice and urban regeneration. But despite this substantial, influential and growing activity, the concept remains largely unknown to policymakers and researchers within the energy field. This paper defines EBPP, identifies its key features and examines the potential role of systematic reviews of evidence in a particular area of policy. It summarises the methods through which systematic reviews are achieved; discusses their advantages and limitations; identifies the particular challenges they face in the energy policy area; and assesses whether and to what extent they can usefully be applied to contemporary energy policy questions. The concept is illustrated with reference to a proposed review of evidence for a 'rebound effect' from improved energy efficiency. The paper concludes that systematic reviews may only be appropriate for a subset of energy policy questions and that research-funding priorities may need to change if their use is to become more widespread

An Object-Oriented Information Model for Policy-based Management of Distributed Applications

NARCIS (Netherlands)

Diaz, G.; Gay, V.C.J.; Horlait, E.; Hamza, M.H.

2002-01-01

This paper presents an object-oriented information model to support a policy-based management for distributed multimedia applications. The information base contains application-level information about the users, the applications, and their profile. Our Information model is described in details and

Dynamic Pressure Gradient Model of Axial Piston Pump and Parameters Optimization

Directory of Open Access Journals (Sweden)

Shi Jian

2014-01-01

Full Text Available The unsteady pressure gradient can cause flow noise in prepressure rising of piston pump, and the fluid shock comes up due to the large pressure difference of the piston chamber and discharge port in valve plate. The flow fluctuation control is the optimization objective in previous study, which cannot ensure the steady pressure gradient. Our study is to stabilize the pressure gradient in prepressure rising and control the pressure of piston chamber approaching to the pressure in discharge port after prepressure rising. The models for nonoil shock and dynamic pressure of piston chamber in prepressure rising are established. The parameters of prepressure rising angle, cross angle, wrap angle of V-groove, vertex angle of V-groove, and opening angle of V-groove were optimized, based on which the pressure of the piston chamber approached the pressure in discharge port after prepressure rising, and the pressure gradient is more steady compared to the original parameters. The max pressure gradient decreased by 70.8% and the flow fluctuation declined by 21.4%, which showed the effectivness of optimization.

Condition-based inspection/replacement policies for non-monotone deteriorating systems with environmental covariates

Energy Technology Data Exchange (ETDEWEB)

Zhao Xuejing [Universite de Technologie de Troyes, Institut Charles Delaunay and STMR UMR CNRS 6279, 12 rue Marie Curie, 10010 Troyes (France); School of mathematics and statistics, Lanzhou University, Lanzhou 730000 (China); Fouladirad, Mitra, E-mail: mitra.fouladirad@utt.f [Universite de Technologie de Troyes, Institut Charles Delaunay and STMR UMR CNRS 6279, 12 rue Marie Curie, 10010 Troyes (France); Berenguer, Christophe [Universite de Technologie de Troyes, Institut Charles Delaunay and STMR UMR CNRS 6279, 12 rue Marie Curie, 10010 Troyes (France); Bordes, Laurent [Universite de Pau et des Pays de l' Adour, LMA UMR CNRS 5142, 64013 PAU Cedex (France)

2010-08-15

The aim of this paper is to discuss the problem of modelling and optimising condition-based maintenance policies for a deteriorating system in presence of covariates. The deterioration is modelled by a non-monotone stochastic process. The covariates process is assumed to be a time-homogenous Markov chain with finite state space. A model similar to the proportional hazards model is used to show the influence of covariates on the deterioration. In the framework of the system under consideration, an appropriate inspection/replacement policy which minimises the expected average maintenance cost is derived. The average cost under different conditions of covariates and different maintenance policies is analysed through simulation experiments to compare the policies performances.

Condition-based inspection/replacement policies for non-monotone deteriorating systems with environmental covariates

International Nuclear Information System (INIS)

Zhao Xuejing; Fouladirad, Mitra; Berenguer, Christophe; Bordes, Laurent

2010-01-01

The aim of this paper is to discuss the problem of modelling and optimising condition-based maintenance policies for a deteriorating system in presence of covariates. The deterioration is modelled by a non-monotone stochastic process. The covariates process is assumed to be a time-homogenous Markov chain with finite state space. A model similar to the proportional hazards model is used to show the influence of covariates on the deterioration. In the framework of the system under consideration, an appropriate inspection/replacement policy which minimises the expected average maintenance cost is derived. The average cost under different conditions of covariates and different maintenance policies is analysed through simulation experiments to compare the policies performances.

Detection of human DNA polymorphisms with a simplified denaturing gradient gel electrophoresis technique.

OpenAIRE

Noll, W W; Collins, M

1987-01-01

Single base pair differences between otherwise identical DNA molecules can result in altered melting behavior detectable by denaturing gradient gel electrophoresis. We have developed a simplified procedure for using denaturing gradient gel electrophoresis to detect base pair changes in genomic DNA. Genomic DNA is digested with restriction enzymes and hybridized in solution to labeled single-stranded probe DNA. The excess probe is then hybridized to complementary phage M13 template DNA, and th...

INVESTIGATION OF FISCAL AND BUDGETARY POLICIES BASED ON ECONOMIC THEORIES

Directory of Open Access Journals (Sweden)

EMILIA CAMPEANU

2011-04-01

Full Text Available Empirical analysis of fiscal and budgetary policies cannot be achieved without first knowing how they are viewed in the economic theories. This approach is important to indicate the position and implications of fiscal and budgetary policy tools in the economic theory considering their major differences. Therefore, the paper aims is to investigate the fiscal and budgetary policies based on economic theories such as neoclassical, Keynesian and neo-Keynesian theory in order to indicate their divergent points. Once known these approaches at the economic theory level is easier to establish the appropriate measures taking into consideration the framing of a country economy in a certain pattern. This work was supported from the European Social Fund through Sectoral Operational Programme Human Resources Development 2007-2013, project number POSDRU/89/1.5/S/59184 „Performance and excellence in postdoctoral research in Romanian economics science domain” (contract no. 0501/01.11.2010.

Uniform gradient expansions

CERN Document Server

Giovannini, Massimo

2015-01-01

Cosmological singularities are often discussed by means of a gradient expansion that can also describe, during a quasi-de Sitter phase, the progressive suppression of curvature inhomogeneities. While the inflationary event horizon is being formed the two mentioned regimes coexist and a uniform expansion can be conceived and applied to the evolution of spatial gradients across the protoinflationary boundary. It is argued that conventional arguments addressing the preinflationary initial conditions are necessary but generally not sufficient to guarantee a homogeneous onset of the conventional inflationary stage.

Monitoring of the spatio-temporal change in the interplate coupling at northeastern Japan subduction zone based on the spatial gradients of surface velocity field

Science.gov (United States)

Iinuma, Takeshi

2018-04-01

A monitoring method to grasp the spatio-temporal change in the interplate coupling in a subduction zone based on the spatial gradients of surface displacement rate fields is proposed. I estimated the spatio-temporal change in the interplate coupling along the plate boundary in northeastern (NE) Japan by applying the proposed method to the surface displacement rates based on global positioning system observations. The gradient of the surface velocities is calculated in each swath configured along the direction normal to the Japan Trench for time windows such as 0.5, 1, 2, 3 and 5 yr being shifted by one week during the period of 1997-2016. The gradient of the horizontal velocities is negative and has a large magnitude when the interplate coupling at the shallow part (less than approximately 50 km in depth) beneath the profile is strong, and the sign of the gradient of the vertical velocity is sensitive to the existence of the coupling at the deep part (greater than approximately 50 km in depth). The trench-parallel variation of the spatial gradients of a displacement rate field clearly corresponds to the trench-parallel variation of the amplitude of the interplate coupling on the plate interface, as well as the rupture areas of previous interplate earthquakes. Temporal changes in the trench-parallel variation of the spatial gradient of the displacement rate correspond to the strengthening or weakening of the interplate coupling. We can monitor the temporal change in the interplate coupling state by calculating the spatial gradients of the surface displacement rate field to some extent without performing inversion analyses with applying certain constraint conditions that sometimes cause over- and/or underestimation at areas of limited spatial resolution far from the observation network. The results of the calculation confirm known interplate events in the NE Japan subduction zone, such as the post-seismic slip of the 2003 M8.0 Tokachi-oki and 2005 M7.2 Miyagi

Gradient Flow Convolutive Blind Source Separation

DEFF Research Database (Denmark)

Pedersen, Michael Syskind; Nielsen, Chinton Møller

2004-01-01

Experiments have shown that the performance of instantaneous gradient flow beamforming by Cauwenberghs et al. is reduced significantly in reverberant conditions. By expanding the gradient flow principle to convolutive mixtures, separation in a reverberant environment is possible. By use...... of a circular four microphone array with a radius of 5 mm, and applying convolutive gradient flow instead of just applying instantaneous gradient flow, experimental results show an improvement of up to around 14 dB can be achieved for simulated impulse responses and up to around 10 dB for a hearing aid...

An implicit tensorial gradient plasticity model - formulation and comparison with a scalar gradient model

NARCIS (Netherlands)

Poh, L.H.; Peerlings, R.H.J.; Geers, M.G.D.; Swaddiwudhipong, S.

2011-01-01

Many rate-independent models for metals utilize the gradient of effective plastic strain to capture size-dependent behavior. This enhancement, sometimes termed as "explicit" gradient formulation, requires higher-order tractions to be imposed on the evolving elasto-plastic boundary and the resulting

High Gradient Accelerator Research

International Nuclear Information System (INIS)

Temkin, Richard

2016-01-01

The goal of the MIT program of research on high gradient acceleration is the development of advanced acceleration concepts that lead to a practical and affordable next generation linear collider at the TeV energy level. Other applications, which are more near-term, include accelerators for materials processing; medicine; defense; mining; security; and inspection. The specific goals of the MIT program are: • Pioneering theoretical research on advanced structures for high gradient acceleration, including photonic structures and metamaterial structures; evaluation of the wakefields in these advanced structures • Experimental research to demonstrate the properties of advanced structures both in low-power microwave cold test and high-power, high-gradient test at megawatt power levels • Experimental research on microwave breakdown at high gradient including studies of breakdown phenomena induced by RF electric fields and RF magnetic fields; development of new diagnostics of the breakdown process • Theoretical research on the physics and engineering features of RF vacuum breakdown • Maintaining and improving the Haimson / MIT 17 GHz accelerator, the highest frequency operational accelerator in the world, a unique facility for accelerator research • Providing the Haimson / MIT 17 GHz accelerator facility as a facility for outside users • Active participation in the US DOE program of High Gradient Collaboration, including joint work with SLAC and with Los Alamos National Laboratory; participation of MIT students in research at the national laboratories • Training the next generation of Ph. D. students in the field of accelerator physics.

The temporal distribution of directional gradients under selection for an optimum.

Science.gov (United States)

Chevin, Luis-Miguel; Haller, Benjamin C

2014-12-01

Temporal variation in phenotypic selection is often attributed to environmental change causing movements of the adaptive surface relating traits to fitness, but this connection is rarely established empirically. Fluctuating phenotypic selection can be measured by the variance and autocorrelation of directional selection gradients through time. However, the dynamics of these gradients depend not only on environmental changes altering the fitness surface, but also on evolution of the phenotypic distribution. Therefore, it is unclear to what extent variability in selection gradients can inform us about the underlying drivers of their fluctuations. To investigate this question, we derive the temporal distribution of directional gradients under selection for a phenotypic optimum that is either constant or fluctuates randomly in various ways in a finite population. Our analytical results, combined with population- and individual-based simulations, show that although some characteristic patterns can be distinguished, very different types of change in the optimum (including a constant optimum) can generate similar temporal distributions of selection gradients, making it difficult to infer the processes underlying apparent fluctuating selection. Analyzing changes in phenotype distributions together with changes in selection gradients should prove more useful for inferring the mechanisms underlying estimated fluctuating selection. © 2014 The Author(s). Evolution © 2014 The Society for the Study of Evolution.

Effects of Gradient Coil Noise and Gradient Coil Replacement on the Reproducibility of Resting State Networks.

Science.gov (United States)

Bagarinao, Epifanio; Tsuzuki, Erina; Yoshida, Yukina; Ozawa, Yohei; Kuzuya, Maki; Otani, Takashi; Koyama, Shuji; Isoda, Haruo; Watanabe, Hirohisa; Maesawa, Satoshi; Naganawa, Shinji; Sobue, Gen

2018-01-01

The stability of the MRI scanner throughout a given study is critical in minimizing hardware-induced variability in the acquired imaging data set. However, MRI scanners do malfunction at times, which could generate image artifacts and would require the replacement of a major component such as its gradient coil. In this article, we examined the effect of low intensity, randomly occurring hardware-related noise due to a faulty gradient coil on brain morphometric measures derived from T1-weighted images and resting state networks (RSNs) constructed from resting state functional MRI. We also introduced a method to detect and minimize the effect of the noise associated with a faulty gradient coil. Finally, we assessed the reproducibility of these morphometric measures and RSNs before and after gradient coil replacement. Our results showed that gradient coil noise, even at relatively low intensities, could introduce a large number of voxels exhibiting spurious significant connectivity changes in several RSNs. However, censoring the affected volumes during the analysis could minimize, if not completely eliminate, these spurious connectivity changes and could lead to reproducible RSNs even after gradient coil replacement.

An Investigation into the Effects of Temperature Gradient on the Soil Water–Salt Transfer with Evaporation

Directory of Open Access Journals (Sweden)

Rong Ren

2017-06-01

Full Text Available Temperature gradients exist in the field under brackish water irrigation conditions, especially in northern semi–arid areas of China. Although there are many investigators dedicated to studying the mechanism of brackish water irrigation and the effect of brackish water irrigation on crops, there are fewer investigations of the effects of temperature gradient on the water–salt transport. Based on the combination of a physical experiment and a mathematical model, this study was conducted to: (a build a physical model and observe the redistribution of soil water–heat–salt transfer; (b develop a mathematical model focused on the influence of a temperature gradient on soil water and salt redistribution based on the physical model and validate the proposed model using the measured data; and (c analyze the effects of the temperature gradient on the soil water–salt transport by comparing the proposed model with the traditional water–salt model in which the effects of temperature gradient on the soil water–salt transfer are neglected. Results show that the soil temperature gradient has a definite influence on the soil water–salt migration. Moreover, the effect of temperature gradient on salt migration was greater than that of water movement.

Sustaining School-Based Asthma Interventions through Policy and Practice Change

Science.gov (United States)

Carpenter, Laurie M.; Lachance, Laurie; Wilkin, Margaret; Clark, Noreen M.

2013-01-01

Background: Schools are an ideal setting for implementation of asthma interventions for children; however, sustaining school-based programs can be challenging. This study illustrates policy and practice changes brought about through the Childhood Asthma Linkages in Missouri (CALM) program to sustain such programs. Methods: Researchers analyzed…

Strategies and applications for incorporating physical and chemical signal gradients in tissue engineering.

Science.gov (United States)

Singh, Milind; Berkland, Cory; Detamore, Michael S

2008-12-01

From embryonic development to wound repair, concentration gradients of bioactive signaling molecules guide tissue formation and regeneration. Moreover, gradients in cellular and extracellular architecture as well as in mechanical properties are readily apparent in native tissues. Perhaps tissue engineers can take a cue from nature in attempting to regenerate tissues by incorporating gradients into engineering design strategies. Indeed, gradient-based approaches are an emerging trend in tissue engineering, standing in contrast to traditional approaches of homogeneous delivery of cells and/or growth factors using isotropic scaffolds. Gradients in tissue engineering lie at the intersection of three major paradigms in the field-biomimetic, interfacial, and functional tissue engineering-by combining physical (via biomaterial design) and chemical (with growth/differentiation factors and cell adhesion molecules) signal delivery to achieve a continuous transition in both structure and function. This review consolidates several key methodologies to generate gradients, some of which have never been employed in a tissue engineering application, and discusses strategies for incorporating these methods into tissue engineering and implant design. A key finding of this review was that two-dimensional physicochemical gradient substrates, which serve as excellent high-throughput screening tools for optimizing desired biomaterial properties, can be enhanced in the future by transitioning from two dimensions to three dimensions, which would enable studies of cell-protein-biomaterial interactions in a more native tissue-like environment. In addition, biomimetic tissue regeneration via combined delivery of graded physical and chemical signals appears to be a promising strategy for the regeneration of heterogeneous tissues and tissue interfaces. In the future, in vivo applications will shed more light on the performance of gradient-based mechanical integrity and signal delivery

Tearing modes with pressure gradient effect in pair plasmas

International Nuclear Information System (INIS)

Cai Huishan; Li Ding; Zheng Jian

2009-01-01

The general dispersion relation of tearing mode with pressure gradient effect in pair plasmas is derived analytically. If the pressure gradients of positron and electron are not identical in pair plasmas, the pressure gradient has significant influence at tearing mode in both collisionless and collisional regimes. In collisionless regime, the effects of pressure gradient depend on its magnitude. For small pressure gradient, the growth rate of tearing mode is enhanced by pressure gradient. For large pressure gradient, the growth rate is reduced by pressure gradient. The tearing mode can even be stabilized if pressure gradient is large enough. In collisional regime, the growth rate of tearing mode is reduced by the pressure gradient. While the positron and electron have equal pressure gradient, tearing mode is not affected by pressure gradient in pair plasmas.

Analysis and correction of gradient nonlinearity bias in apparent diffusion coefficient measurements.

Science.gov (United States)

Malyarenko, Dariya I; Ross, Brian D; Chenevert, Thomas L

2014-03-01

Gradient nonlinearity of MRI systems leads to spatially dependent b-values and consequently high non-uniformity errors (10-20%) in apparent diffusion coefficient (ADC) measurements over clinically relevant field-of-views. This work seeks practical correction procedure that effectively reduces observed ADC bias for media of arbitrary anisotropy in the fewest measurements. All-inclusive bias analysis considers spatial and time-domain cross-terms for diffusion and imaging gradients. The proposed correction is based on rotation of the gradient nonlinearity tensor into the diffusion gradient frame where spatial bias of b-matrix can be approximated by its Euclidean norm. Correction efficiency of the proposed procedure is numerically evaluated for a range of model diffusion tensor anisotropies and orientations. Spatial dependence of nonlinearity correction terms accounts for the bulk (75-95%) of ADC bias for FA = 0.3-0.9. Residual ADC non-uniformity errors are amplified for anisotropic diffusion. This approximation obviates need for full diffusion tensor measurement and diagonalization to derive a corrected ADC. Practical scenarios are outlined for implementation of the correction on clinical MRI systems. The proposed simplified correction algorithm appears sufficient to control ADC non-uniformity errors in clinical studies using three orthogonal diffusion measurements. The most efficient reduction of ADC bias for anisotropic medium is achieved with non-lab-based diffusion gradients. Copyright © 2013 Wiley Periodicals, Inc.

One Dimension Analytical Model of Normal Ballistic Impact on Ceramic/Metal Gradient Armor

International Nuclear Information System (INIS)

Liu Lisheng; Zhang Qingjie; Zhai Pengcheng; Cao Dongfeng

2008-01-01

An analytical model of normal ballistic impact on the ceramic/metal gradient armor, which is based on modified Alekseevskii-Tate equations, has been developed. The process of gradient armour impacted by the long rod can be divided into four stages in this model. First stage is projectile's mass erosion or flowing phase, mushrooming phase and rigid phase; second one is the formation of comminuted ceramic conoid; third one is the penetration of gradient layer and last one is the penetration of metal back-up plate. The equations of third stage have been advanced by assuming the behavior of gradient layer as rigid-plastic and considering the effect of strain rate on the dynamic yield strength

One Dimension Analytical Model of Normal Ballistic Impact on Ceramic/Metal Gradient Armor

Science.gov (United States)

Liu, Lisheng; Zhang, Qingjie; Zhai, Pengcheng; Cao, Dongfeng

2008-02-01

An analytical model of normal ballistic impact on the ceramic/metal gradient armor, which is based on modified Alekseevskii-Tate equations, has been developed. The process of gradient armour impacted by the long rod can be divided into four stages in this model. First stage is projectile's mass erosion or flowing phase, mushrooming phase and rigid phase; second one is the formation of comminuted ceramic conoid; third one is the penetration of gradient layer and last one is the penetration of metal back-up plate. The equations of third stage have been advanced by assuming the behavior of gradient layer as rigid-plastic and considering the effect of strain rate on the dynamic yield strength.

National Drought Policy: Shifting the Paradigm from Crisis to Risk-based Management

Science.gov (United States)

Wilhite, D. A.; Sivakumar, M. K.; Stefanski, R.

2011-12-01

Drought is a normal part of climate for virtually all of the world's climatic regimes. To better address the risks associated with this hazard and societal vulnerability, there must be a dramatic paradigm shift in our approach to drought management in the coming decade in the light of the increasing frequency of droughts and projections of increased severity and duration of these events in the future for many regions, especially in the developing world. Addressing this challenge will require an improved awareness of drought as a natural hazard, the establishment of integrated drought monitoring and early warning systems, a higher level of preparedness that fully incorporates risk-based management, and the adoption of national drought policies that are directed at increasing the coping capacity and resilience of populations to future drought episodes. The World Meteorological Organization (WMO), in partnership with other United Nations' agencies, the National Drought Mitigation Center at the University of Nebraska, NOAA, the U.S. Department of Agriculture, and other partners, is currently launching a program to organize a High Level Meeting on National Drought Policy (HMNDP) in March 2013 to encourage the development of national drought policies through the development of a compendium of key policy elements. The key objectives of a national drought policy are to: (1) encourage vulnerable economic sectors and population groups to adopt self-reliant measures that promote risk management; (2) promote sustainable use of the agricultural and natural resource base; and (3) facilitate early recovery from drought through actions consistent with national drought policy objectives. The key elements of a drought policy framework are policy and governance, including political will; addressing risk and improving early warnings, including vulnerability analysis, impact assessment, and communication; mitigation and preparedness, including the application of effective and

Optimization in Quaternion Dynamic Systems: Gradient, Hessian, and Learning Algorithms.

Science.gov (United States)

Xu, Dongpo; Xia, Yili; Mandic, Danilo P

2016-02-01

The optimization of real scalar functions of quaternion variables, such as the mean square error or array output power, underpins many practical applications. Solutions typically require the calculation of the gradient and Hessian. However, real functions of quaternion variables are essentially nonanalytic, which are prohibitive to the development of quaternion-valued learning systems. To address this issue, we propose new definitions of quaternion gradient and Hessian, based on the novel generalized Hamilton-real (GHR) calculus, thus making a possible efficient derivation of general optimization algorithms directly in the quaternion field, rather than using the isomorphism with the real domain, as is current practice. In addition, unlike the existing quaternion gradients, the GHR calculus allows for the product and chain rule, and for a one-to-one correspondence of the novel quaternion gradient and Hessian with their real counterparts. Properties of the quaternion gradient and Hessian relevant to numerical applications are also introduced, opening a new avenue of research in quaternion optimization and greatly simplified the derivations of learning algorithms. The proposed GHR calculus is shown to yield the same generic algorithm forms as the corresponding real- and complex-valued algorithms. Advantages of the proposed framework are illuminated over illustrative simulations in quaternion signal processing and neural networks.

Frequency-domain beamformers using conjugate gradient techniques for speech enhancement.

Science.gov (United States)

Zhao, Shengkui; Jones, Douglas L; Khoo, Suiyang; Man, Zhihong

2014-09-01

A multiple-iteration constrained conjugate gradient (MICCG) algorithm and a single-iteration constrained conjugate gradient (SICCG) algorithm are proposed to realize the widely used frequency-domain minimum-variance-distortionless-response (MVDR) beamformers and the resulting algorithms are applied to speech enhancement. The algorithms are derived based on the Lagrange method and the conjugate gradient techniques. The implementations of the algorithms avoid any form of explicit or implicit autocorrelation matrix inversion. Theoretical analysis establishes formal convergence of the algorithms. Specifically, the MICCG algorithm is developed based on a block adaptation approach and it generates a finite sequence of estimates that converge to the MVDR solution. For limited data records, the estimates of the MICCG algorithm are better than the conventional estimators and equivalent to the auxiliary vector algorithms. The SICCG algorithm is developed based on a continuous adaptation approach with a sample-by-sample updating procedure and the estimates asymptotically converge to the MVDR solution. An illustrative example using synthetic data from a uniform linear array is studied and an evaluation on real data recorded by an acoustic vector sensor array is demonstrated. Performance of the MICCG algorithm and the SICCG algorithm are compared with the state-of-the-art approaches.

Detection of human DNA polymorphisms with a simplified denaturing gradient gel electrophoresis technique

International Nuclear Information System (INIS)

Noll, W.W.; Collins, M.

1987-01-01

Single base pair differences between otherwise identical DNA molecules can result in altered melting behavior detectable by denaturing gradient gel electrophoresis. The authors have developed a simplified procedure for using denaturing gradient gel electrophoresis to detect base pair changes in genomic DNA. Genomic DNA is digested with restriction enzymes and hybridized in solution to labeled single-stranded probe DNA. The excess probe is then hybridized to complementary phage M13 template DNA, and the reaction mixture is electrophoresed on a denaturing gradient gel. Only the genomic DNA probe hybrids migrate into the gel. Differences in hybrid mobility on the gel indicate base pair changes in the genomic DNA. They have used this technique to identify two polymorphic sites within a 1.2-kilobase region of human chromosome 20. This approach should greatly facilitate the identification of DNA polymorphisms useful for gene linkage studies and the diagnosis of genetic diseases

Dynamic analysis of the urban-based low-carbon policy using system dynamics: Focused on housing and green space

Energy Technology Data Exchange (ETDEWEB)

Hong, Taehoon, E-mail: hong7@yonsei.ac.kr [Associate Professor, Department of Architectural Engineering, Yonsei University, Seoul, 120-749 (Korea, Republic of); Kim, Jimin, E-mail: cookie6249@yonsei.ac.kr; Jeong, Kwangbok, E-mail: kbjeong7@yonsei.ac.kr [Research Assistant and Ph.D. Student, Department of Architectural Engineering, Yonsei University, Seoul, 120-749 (Korea, Republic of); Koo, Choongwan, E-mail: cwkoo@yonsei.ac.kr [Postdoctoral Fellow, Department of Architectural Engineering, Yonsei University, Seoul, 120-749 (Korea, Republic of)

2015-02-09

To systematically manage the energy consumption of existing buildings, the government has to enforce greenhouse gas reduction policies. However, most of the policies are not properly executed because they do not consider various factors from the urban level perspective. Therefore, this study aimed to conduct a dynamic analysis of an urban-based low-carbon policy using system dynamics, with a specific focus on housing and green space. This study was conducted in the following steps: (i) establishing the variables of urban-based greenhouse gases (GHGs) emissions; (ii) creating a stock/flow diagram of urban-based GHGs emissions; (iii) conducting an information analysis using the system dynamics; and (iv) proposing the urban-based low-carbon policy. If a combined energy policy that uses the housing sector (30%) and the green space sector (30%) at the same time is implemented, 2020 CO{sub 2} emissions will be 7.23 million tons (i.e., 30.48% below 2020 business-as-usual), achieving the national carbon emissions reduction target (26.9%). The results of this study could contribute to managing and improving the fundamentals of the urban-based low-carbon policies to reduce greenhouse gas emissions.

Dynamic analysis of the urban-based low-carbon policy using system dynamics: Focused on housing and green space

International Nuclear Information System (INIS)

Hong, Taehoon; Kim, Jimin; Jeong, Kwangbok; Koo, Choongwan

2015-01-01

To systematically manage the energy consumption of existing buildings, the government has to enforce greenhouse gas reduction policies. However, most of the policies are not properly executed because they do not consider various factors from the urban level perspective. Therefore, this study aimed to conduct a dynamic analysis of an urban-based low-carbon policy using system dynamics, with a specific focus on housing and green space. This study was conducted in the following steps: (i) establishing the variables of urban-based greenhouse gases (GHGs) emissions; (ii) creating a stock/flow diagram of urban-based GHGs emissions; (iii) conducting an information analysis using the system dynamics; and (iv) proposing the urban-based low-carbon policy. If a combined energy policy that uses the housing sector (30%) and the green space sector (30%) at the same time is implemented, 2020 CO 2 emissions will be 7.23 million tons (i.e., 30.48% below 2020 business-as-usual), achieving the national carbon emissions reduction target (26.9%). The results of this study could contribute to managing and improving the fundamentals of the urban-based low-carbon policies to reduce greenhouse gas emissions

Gradient elution behavior of proteins in hydrophobic interaction chromatography with U-shaped retention factor curves.

Science.gov (United States)

Creasy, Arch; Lomino, Joseph; Barker, Gregory; Khetan, Anurag; Carta, Giorgio

2018-04-27

Protein retention in hydrophobic interaction chromatography is described by the solvophobic theory as a function of the kosmostropic salt concentration. In general, an increase in salt concentration drives protein partitioning to the hydrophobic surface while a decrease reduces it. In some cases, however, protein retention also increases at low salt concentrations resulting in a U-shaped retention factor curve. During gradient elution the salt concentration is gradually decreased from a high value thereby reducing the retention factor and increasing the protein chromatographic velocity. For these conditions, a steep gradient can overtake the protein in the column, causing it to rebind. Two dynamic models, one based on the local equilibrium theory and the other based on the linear driving force approximation, are presented. We show that the normalized gradient slope determines whether the protein elutes in the gradient, partially elutes, or is trapped in the column. Experimental results are presented for two different monoclonal antibodies and for lysozyme on Capto Phenyl (High Sub) resin. One of the mAbs and lysozyme exhibit U-shaped retention factor curves and for each, we determine the critical gradient slope beyond which 100% recovery is no longer possible. Elution with a reverse gradient is also demonstrated at low salt concentrations for these proteins. Understanding this behavior has implications in the design of gradient elution since the gradient slope impacts protein recovery. Copyright © 2018 Elsevier B.V. All rights reserved.

Evidence of counter-gradient growth in western pond turtles (Actinemys marmorata) across thermal gradients

Science.gov (United States)

Snover, Melissa; Adams, Michael J.; Ashton, Donald T.; Bettaso, Jamie B.; Welsh, Hartwell H.

2015-01-01

Counter-gradient growth, where growth per unit temperature increases as temperature decreases, can reduce the variation in ectothermic growth rates across environmental gradients. Understanding how ectothermic species respond to changing temperatures is essential to their conservation and management due to human-altered habitats and changing climates.

Fostering integrity in postgraduate research: an evidence-based policy and support framework.

Science.gov (United States)

Mahmud, Saadia; Bretag, Tracey

2014-01-01

Postgraduate research students have a unique position in the debate on integrity in research as students and novice researchers. To assess how far policies for integrity in postgraduate research meet the needs of students as "research trainees," we reviewed online policies for integrity in postgraduate research at nine particular Australian universities against the Australian Code for Responsible Conduct of Research (the Code) and the five core elements of exemplary academic integrity policy identified by Bretag et al. (2011 ), i.e., access, approach, responsibility, detail, and support. We found inconsistency with the Code in the definition of research misconduct and a lack of adequate detail and support. Based on our analysis, previous research, and the literature, we propose a framework for policy and support for postgraduate research that encompasses a consistent and educative approach to integrity maintained across the university at all levels of scholarship and for all stakeholders.

A Robust Gradient Based Method for Building Extraction from LiDAR and Photogrammetric Imagery

Directory of Open Access Journals (Sweden)

Fasahat Ullah Siddiqui

2016-07-01

Full Text Available Existing automatic building extraction methods are not effective in extracting buildings which are small in size and have transparent roofs. The application of large area threshold prohibits detection of small buildings and the use of ground points in generating the building mask prevents detection of transparent buildings. In addition, the existing methods use numerous parameters to extract buildings in complex environments, e.g., hilly area and high vegetation. However, the empirical tuning of large number of parameters reduces the robustness of building extraction methods. This paper proposes a novel Gradient-based Building Extraction (GBE method to address these limitations. The proposed method transforms the Light Detection And Ranging (LiDAR height information into intensity image without interpolation of point heights and then analyses the gradient information in the image. Generally, building roof planes have a constant height change along the slope of a roof plane whereas trees have a random height change. With such an analysis, buildings of a greater range of sizes with a transparent or opaque roof can be extracted. In addition, a local colour matching approach is introduced as a post-processing stage to eliminate trees. This stage of our proposed method does not require any manual setting and all parameters are set automatically from the data. The other post processing stages including variance, point density and shadow elimination are also applied to verify the extracted buildings, where comparatively fewer empirically set parameters are used. The performance of the proposed GBE method is evaluated on two benchmark data sets by using the object and pixel based metrics (completeness, correctness and quality. Our experimental results show the effectiveness of the proposed method in eliminating trees, extracting buildings of all sizes, and extracting buildings with and without transparent roof. When compared with current state

Spatial gradient tuning in metamaterials

Science.gov (United States)

Driscoll, Tom; Goldflam, Michael; Jokerst, Nan; Basov, Dimitri; Smith, David

2011-03-01

Gradient Index (GRIN) metamaterials have been used to create devices inspired by, but often surpassing the potential of, conventional GRIN optics. The unit-cell nature of metamaterials presents the opportunity to exert much greater control over spatial gradients than is possible in natural materials. This is true not only during the design phase but also offers the potential for real-time reconfiguration of the metamaterial gradient. This ability fits nicely into the picture of transformation-optics, in which spatial gradients can enable an impressive suite of innovative devices. We discuss methods to exert control over metamaterial response, focusing on our recent demonstrations using Vanadium Dioxide. We give special attention to role of memristance and mem-capacitance observed in Vanadium Dioxide, which simplify the demands of stimuli and addressing, as well as intersecting metamaterials with the field of memory-materials.

Transformation of Croatian Disabled Policy: Analysis of Policy Goals

Directory of Open Access Journals (Sweden)

Ana Petek

2010-01-01

Full Text Available The article is based on the idea of transformation of the policy-making mode of Croatian disabled policy, from the medical model, through the social model to the human rights model. The paper highlights 7 elements according to which these models differ, and which are structured into categories of problem-definition, goal-determination and then implementation of disabled policy. The analysis is focused on the goals of Croatian disabled policy, and is based on an interdisciplinary research project of political science, special education and social work. Empirical data were collected by document analysis, by interviewing relevant policy actors and by a survey with the members of representative bodies on all government levels. With the discourse analysis of documents, open coding of interviews and statistical analysis of data collected in the survey, the paper attempts, through the indicator of activity of persons with disability, to answer to what extent Croatian disabled policy is transformed into human rights policy.

Feedback-Based Projected-Gradient Method For Real-Time Optimization of Aggregations of Energy Resources: Preprint

Energy Technology Data Exchange (ETDEWEB)

Dall-Anese, Emiliano [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Bernstein, Andrey [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Simonetto, Andrea [IBM Research Center Ireland

2017-11-27

This paper develops an online optimization method to maximize the operational objectives of distribution-level distributed energy resources (DERs) while adjusting the aggregate power generated (or consumed) in response to services requested by grid operators. The design of the online algorithm is based on a projected-gradient method, suitably modified to accommodate appropriate measurements from the distribution network and the DERs. By virtue of this approach, the resultant algorithm can cope with inaccuracies in the representation of the AC power, it avoids pervasive metering to gather the state of noncontrollable resources, and it naturally lends itself to a distributed implementation. Optimality claims are established in terms of tracking of the solution of a well-posed time-varying optimization problem.

A novel technique for real-time estimation of edge pedestal density gradients via reflectometer time delay data

Energy Technology Data Exchange (ETDEWEB)

Zeng, L., E-mail: zeng@fusion.gat.com; Doyle, E. J.; Rhodes, T. L.; Wang, G.; Sung, C.; Peebles, W. A. [Physics and Astronomy Department, University of California, Los Angeles, California 90095 (United States); Bobrek, M. [Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831-6006 (United States)

2016-11-15

A new model-based technique for fast estimation of the pedestal electron density gradient has been developed. The technique uses ordinary mode polarization profile reflectometer time delay data and does not require direct profile inversion. Because of its simple data processing, the technique can be readily implemented via a Field-Programmable Gate Array, so as to provide a real-time density gradient estimate, suitable for use in plasma control systems such as envisioned for ITER, and possibly for DIII-D and Experimental Advanced Superconducting Tokamak. The method is based on a simple edge plasma model with a linear pedestal density gradient and low scrape-off-layer density. By measuring reflectometer time delays for three adjacent frequencies, the pedestal density gradient can be estimated analytically via the new approach. Using existing DIII-D profile reflectometer data, the estimated density gradients obtained from the new technique are found to be in good agreement with the actual density gradients for a number of dynamic DIII-D plasma conditions.

Gradient-based estimation of Manning's friction coefficient from noisy data

KAUST Repository

Calo, Victor M.

2013-01-01

We study the numerical recovery of Manning\\'s roughness coefficient for the diffusive wave approximation of the shallow water equation. We describe a conjugate gradient method for the numerical inversion. Numerical results for one-dimensional models are presented to illustrate the feasibility of the approach. Also we provide a proof of the differentiability of the weak form with respect to the coefficient as well as the continuity and boundedness of the linearized operator under reasonable assumptions using the maximal parabolic regularity theory. © 2012 Elsevier B.V. All rights reserved.

Accelerated gradient methods for total-variation-based CT image reconstruction

DEFF Research Database (Denmark)

Jørgensen, Jakob Heide; Jensen, Tobias Lindstrøm; Hansen, Per Christian

2011-01-01

incorporates several heuristics from the optimization literature such as Barzilai-Borwein (BB) step size selection and nonmonotone line search. The latter uses a cleverly chosen sequence of auxiliary points to achieve a better convergence rate. The methods are memory efficient and equipped with a stopping...... reconstruction can in principle be found by any optimization method, but in practice the large scale of the systems arising in CT image reconstruction preclude the use of memory-demanding methods such as Newton’s method. The simple gradient method has much lower memory requirements, but exhibits slow convergence...

Gradient-based estimation of Manning's friction coefficient from noisy data

KAUST Repository

Calo, Victor M.; Collier, Nathan; Gehre, Matthias; Jin, Bangti; Radwan, Hany G.; Santillana, Mauricio

2013-01-01

We study the numerical recovery of Manning's roughness coefficient for the diffusive wave approximation of the shallow water equation. We describe a conjugate gradient method for the numerical inversion. Numerical results for one-dimensional models are presented to illustrate the feasibility of the approach. Also we provide a proof of the differentiability of the weak form with respect to the coefficient as well as the continuity and boundedness of the linearized operator under reasonable assumptions using the maximal parabolic regularity theory. © 2012 Elsevier B.V. All rights reserved.

Ultrasonic wave propagation through aberrating layers: experimental verification of the conjugate gradient Rayleigh method

NARCIS (Netherlands)

Ledoux, L.A.F.; Berkhoff, Arthur P.; Thijssen, J.M.

The Conjugate Gradient Rayleigh method for the calculation of acoustic reflection and transmission at a rough interface between two media was experimentally verified. The method is based on a continuous version of the conjugate gradient technique and plane-wave expansions. We measured the beam

Gravity gradient preprocessing at the GOCE HPF

Science.gov (United States)

Bouman, J.; Rispens, S.; Gruber, T.; Schrama, E.; Visser, P.; Tscherning, C. C.; Veicherts, M.

2009-04-01

One of the products derived from the GOCE observations are the gravity gradients. These gravity gradients are provided in the Gradiometer Reference Frame (GRF) and are calibrated in-flight using satellite shaking and star sensor data. In order to use these gravity gradients for application in Earth sciences and gravity field analysis, additional pre-processing needs to be done, including corrections for temporal gravity field signals to isolate the static gravity field part, screening for outliers, calibration by comparison with existing external gravity field information and error assessment. The temporal gravity gradient corrections consist of tidal and non-tidal corrections. These are all generally below the gravity gradient error level, which is predicted to show a 1/f behaviour for low frequencies. In the outlier detection the 1/f error is compensated for by subtracting a local median from the data, while the data error is assessed using the median absolute deviation. The local median acts as a high-pass filter and it is robust as is the median absolute deviation. Three different methods have been implemented for the calibration of the gravity gradients. All three methods use a high-pass filter to compensate for the 1/f gravity gradient error. The baseline method uses state-of-the-art global gravity field models and the most accurate results are obtained if star sensor misalignments are estimated along with the calibration parameters. A second calibration method uses GOCE GPS data to estimate a low degree gravity field model as well as gravity gradient scale factors. Both methods allow to estimate gravity gradient scale factors down to the 10-3 level. The third calibration method uses high accurate terrestrial gravity data in selected regions to validate the gravity gradient scale factors, focussing on the measurement band. Gravity gradient scale factors may be estimated down to the 10-2 level with this method.

Application of preconditioned conjugate gradient-like methods to reactor kinetics

International Nuclear Information System (INIS)

Yang, D.Y.; Chen, G.S.; Chou, H.P.

1993-01-01

Several conjugate gradient-like (CG-like) methods are applied to solve the nonsymmetric linear systems of equations derived from the time-dependent two-dimensional two-energy-group neutron diffusion equations by a finite difference approximation. The methods are: the generalized conjugate residual method; the generalized conjugate gradient least-square method; the generalized minimal residual method (GMRES); the conjugate gradient square method; and a variant of bi-conjugate gradient method (Bi-CGSTAB). In order to accelerate these methods, six preconditioning techniques are investigated. Two are based on pointwise incomplete factorization: the incomplete LU (ILU) and the modified incomplete LU (MILU) decompositions; two, based on the block tridiagonal structure of the coefficient matrix, are blockwise and modified blockwise incomplete factorizations, BILU and MBILU; two are the alternating-direction implicit and symmetric successive overrelaxation (SSOR) preconditioners, derived from the basic iterative schemes. Comparisons are made by using CG-like methods combined with different preconditioners to solve a sequence of time-step reactor transient problems. Numerical tests indicate that preconditioned BI-CGSTAB with the preconditioner MBILU requires less CPU time and fewer iterations than other methods. The preconditioned CG-like methods are less sensitive to the time-step size used than the Chebyshev semi-iteration method and line SOR method. The indication is that the CGS, Bi-CGSTAB and GMRES methods are, on average, better than the other methods in reactor kinetics computation and that a good preconditioner is more important than the choice of CG-like methods. The MILU decomposition based on the conventional row-sum criterion has difficulty yielding a convergent solution and an improved version is introduced. (author)

Agricultural policy, food policy, and communicable disease policy.

Science.gov (United States)

Grant, Wyn

2012-12-01

Food and agricultural policy is an essential element of a communicable disease policy. The European Union has developed a more systematic and broadly based interest in questions of food safety and animal health and welfare linked to modernization of the Common Agricultural Policy, reflected in a new treaty obligation on animal welfare. Following the bovine spongiform encephalopathy crisis, moves were made to create a European competency, but implementation and enforcement resources reside with the member states. The European Animal Health Strategy is meant to lead to an EU animal health law, but this has already been constrained by fiscal austerity. The development of such a law may lead to a lowest common denominator formula that does little to enhance consumer protection or improve animal welfare. This is an inherent risk with top-down forms of Europeanization; more attention should be paid to lessons to be learned from bottom-up initiatives of the type used to counteract the bovine diarrhea virus. There will always be a tension among what is good policy for reducing the incidence of communicable disease, policy that is popular with EU citizens, and policy that is acceptable to member states.

The disparate impact of the ion temperature gradient and the density gradient on edge transport and the low-high transition in tokamaks

International Nuclear Information System (INIS)

Kleva, Robert G.; Guzdar, Parvez N.

2009-01-01

Steepening of the ion temperature gradient in nonlinear fluid simulations of the edge region of a tokamak plasma causes a rapid degradation in confinement. As the density gradient steepens, there is a continuous improvement in confinement analogous to the low (L) to high (H) transition observed in tokamaks. In contrast, as the ion temperature gradient steepens, there is a rapid increase in the particle and energy fluxes and no L-H transition. For a given pressure gradient, confinement always improves when more of the pressure gradient arises from the density gradient, and less of the pressure gradient arises from the ion temperature gradient.

Switching neuronal state: optimal stimuli revealed using a stochastically-seeded gradient algorithm.

Science.gov (United States)

Chang, Joshua; Paydarfar, David

2014-12-01

Inducing a switch in neuronal state using energy optimal stimuli is relevant to a variety of problems in neuroscience. Analytical techniques from optimal control theory can identify such stimuli; however, solutions to the optimization problem using indirect variational approaches can be elusive in models that describe neuronal behavior. Here we develop and apply a direct gradient-based optimization algorithm to find stimulus waveforms that elicit a change in neuronal state while minimizing energy usage. We analyze standard models of neuronal behavior, the Hodgkin-Huxley and FitzHugh-Nagumo models, to show that the gradient-based algorithm: (1) enables automated exploration of a wide solution space, using stochastically generated initial waveforms that converge to multiple locally optimal solutions; and (2) finds optimal stimulus waveforms that achieve a physiological outcome condition, without a priori knowledge of the optimal terminal condition of all state variables. Analysis of biological systems using stochastically-seeded gradient methods can reveal salient dynamical mechanisms underlying the optimal control of system behavior. The gradient algorithm may also have practical applications in future work, for example, finding energy optimal waveforms for therapeutic neural stimulation that minimizes power usage and diminishes off-target effects and damage to neighboring tissue.

Developing consensus-based policy solutions for medicines adherence for Europe: a delphi study

Science.gov (United States)

2012-01-01

Background Non-adherence to prescribed medication is a pervasive problem that can incur serious effects on patients’ health outcomes and well-being, and the availability of resources in healthcare systems. This study aimed to develop practical consensus-based policy solutions to address medicines non-adherence for Europe. Methods A four-round Delphi study was conducted. The Delphi Expert Panel comprised 50 participants from 14 countries and was representative of: patient/carers organisations; healthcare providers and professionals; commissioners and policy makers; academics; and industry representatives. Participants engaged in the study remotely, anonymously and electronically. Participants were invited to respond to open questions about the causes, consequences and solutions to medicines non-adherence. Subsequent rounds refined responses, and sought ratings of the relative importance, and operational and political feasibility of each potential solution to medicines non-adherence. Feedback of individual and group responses was provided to participants after each round. Members of the Delphi Expert Panel and members of the research group participated in a consensus meeting upon completion of the Delphi study to discuss and further refine the proposed policy solutions. Results 43 separate policy solutions to medication non-adherence were agreed by the Panel. 25 policy solutions were prioritised based on composite scores for importance, and operational and political feasibility. Prioritised policy solutions focused on interventions for patients, training for healthcare professionals, and actions to support partnership between patients and healthcare professionals. Few solutions concerned actions by governments, healthcare commissioners, or interventions at the system level. Conclusions Consensus about practical actions necessary to address non-adherence to medicines has been developed for Europe. These actions are also applicable to other regions. Prioritised

Analytical method for optimization of maintenance policy based on available system failure data

International Nuclear Information System (INIS)

Coria, V.H.; Maximov, S.; Rivas-Dávalos, F.; Melchor, C.L.; Guardado, J.L.

2015-01-01

An analytical optimization method for preventive maintenance (PM) policy with minimal repair at failure, periodic maintenance, and replacement is proposed for systems with historical failure time data influenced by a current PM policy. The method includes a new imperfect PM model based on Weibull distribution and incorporates the current maintenance interval T 0 and the optimal maintenance interval T to be found. The Weibull parameters are analytically estimated using maximum likelihood estimation. Based on this model, the optimal number of PM and the optimal maintenance interval for minimizing the expected cost over an infinite time horizon are also analytically determined. A number of examples are presented involving different failure time data and current maintenance intervals to analyze how the proposed analytical optimization method for periodic PM policy performances in response to changes in the distribution of the failure data and the current maintenance interval. - Highlights: • An analytical optimization method for preventive maintenance (PM) policy is proposed. • A new imperfect PM model is developed. • The Weibull parameters are analytically estimated using maximum likelihood. • The optimal maintenance interval and number of PM are also analytically determined. • The model is validated by several numerical examples

A new 3-D ray tracing method based on LTI using successive partitioning of cell interfaces and traveltime gradients

Science.gov (United States)

Zhang, Dong; Zhang, Ting-Ting; Zhang, Xiao-Lei; Yang, Yan; Hu, Ying; Qin, Qian-Qing

2013-05-01

We present a new method of three-dimensional (3-D) seismic ray tracing, based on an improvement to the linear traveltime interpolation (LTI) ray tracing algorithm. This new technique involves two separate steps. The first involves a forward calculation based on the LTI method and the dynamic successive partitioning scheme, which is applied to calculate traveltimes on cell boundaries and assumes a wavefront that expands from the source to all grid nodes in the computational domain. We locate several dynamic successive partition points on a cell's surface, the traveltimes of which can be calculated by linear interpolation between the vertices of the cell's boundary. The second is a backward step that uses Fermat's principle and the fact that the ray path is always perpendicular to the wavefront and follows the negative traveltime gradient. In this process, the first-arriving ray path can be traced from the receiver to the source along the negative traveltime gradient, which can be calculated by reconstructing the continuous traveltime field with cubic B-spline interpolation. This new 3-D ray tracing method is compared with the LTI method and the shortest path method (SPM) through a number of numerical experiments. These comparisons show obvious improvements to computed traveltimes and ray paths, both in precision and computational efficiency.

Photodetachment of negative ion in a gradient electric field near a metal surface

International Nuclear Information System (INIS)

Liu Tian-Qi; Wang De-Hua; Han Cai; Liu Jiang; Liang Dong-Qi; Xie Si-Cheng

2012-01-01

Based on closed-orbit theory, the photodetachment of H − in a gradient electric field near a metal surface is studied. It is demonstrated that the gradient electric field has a significant influence on the photodetachment of negative ions near a metal surface. With the increase of the gradient of the electric field, the oscillation in the photodetachment cross section becomes strengthened. Besides, in contrast to the photodetachment of H − near a metal surface in a uniform electric field, the oscillating amplitude and the oscillating region in the cross section of a gradient electric field also become enlarged. Therefore, we can use the gradient electric field to control the photodetachment of negative ions near a metal surface. We hope that our results will be useful for understanding the photodetachment of negative ions in the vicinity of surfaces, cavities, and ion traps. (atomic and molecular physics)

On modeling micro-structural evolution using a higher order strain gradient continuum theory

DEFF Research Database (Denmark)

El-Naaman, S. A.; Nielsen, K. L.; Niordson, C. F.

2016-01-01

is to improve the micro-structural response predicted using strain gradient crystal plasticity within a continuum mechanics framework. One approach to modeling the dislocation structures observed is through a back stress formulation, which can be related directly to the strain gradient energy. The present work...... the experimentally observed micro-structural behavior, within a framework based on continuous field quantities, poses obvious challenges, since the evolution of dislocation structures is inherently a discrete and discontinuous process. This challenge, in particular, motivates the present study, and the aim...... offers an investigation of constitutive equations for the back stress based on both considerations of the gradient energy, but also includes results obtained from a purely phenomenological starting point. The influence of model parameters is brought out in a parametric study, and it is demonstrated how...

A Case Study of Policies and Procedures to Address Cyberbullying at a Technology-Based Middle School

Science.gov (United States)

Tate, Bettina Polite

2017-01-01

This qualitative case study explored the policies and procedures used to effectively address cyberbullying at a technology-based middle school. The purpose of the study was to gain an in-depth understanding of policies and procedures used to address cyberbullying at a technology-based middle school in the southern United States. The study sought…

Intracellular chemical gradients: morphing principle in bacteria

Directory of Open Access Journals (Sweden)

Endres Robert G

2012-09-01

Full Text Available Abstract Advances in computational biology allow systematic investigations to ascertain whether internal chemical gradients can be maintained in bacteria – an open question at the resolution limit of fluorescence microscopy. While it was previously believed that the small bacterial cell size and fast diffusion in the cytoplasm effectively remove any such gradient, a new computational study published in BMC Biophysics supports the emerging view that gradients can exist. The study arose from the recent observation that phosphorylated CtrA forms a gradient prior to cell division in Caulobacter crescentus, a bacterium known for its complicated cell cycle. Tropini et al. (2012 postulate that such gradients can provide an internal chemical compass, directing protein localization, cell division and cell development. More specifically, they describe biochemical and physical constraints on the formation of such gradients and explore a number of existing bacterial cell morphologies. These chemical gradients may limit in vitro analyses, and may ensure timing control and robustness to fluctuations during critical stages in cell development.

Wood formation from the base to the crown in Pinus radiata: gradients of tracheid wall thickness, wood density, radial growth rate and gene expression

Science.gov (United States)

Sheree Cato; Lisa McMillan; Lloyd Donaldson; Thomas Richardson; Craig Echt; Richard Gardner

2006-01-01

Wood formation was investigated at five heights along the bole for two unrelated trees of Pinus radiataBoth trees showed clear gradients in wood properties from the base to the crown. Cambial cells at the base of the tree were dividing 3.3-fold slower than those at the crown, while the average thickness of cell walls in wood was highest at the base....

Protein gradient films of fibroin and gelatine.

Science.gov (United States)