... IAC) Parents of Kids with Infectious Diseases (PKIDs) Pertussis Frequently Asked Questions Language: English (US) Español (Spanish) ... frecuentes sobre la tosferina Q: Can vaccines prevent pertussis? A: Yes. Vaccines can prevent pertussis, or whooping ...
... Herpes Zoster) Tetanus (Lockjaw) Frequently Asked Questions About Rotavirus What is Rotavirus? Why can dehydration be serious ... I find information about the vaccine? What is Rotavirus? Rotavirus is a highly contagious virus that infects ...
... FCA - A A + A You are here Home LGBT Caregiving: Frequently Asked Questions Order this publication Printer- ... service or organization is open to working with LGBT families? Kudos to you for managing to “go ...
... NCLC 2018 Schedule at a Glance Educational Program Hotel & Travel Exhibitors & Sponsors Conference Policies FAQs 2018 Advocacy ... and Chiropractic Neck Pain and Chiropractic Posture Backpack Safety Spinal Health Winter Activities Kids and Sports Exercising ...
Tattersall, Colin; Manderveld, Jocelyn; Hummel, Hans; Sloep, Peter; Koper, Rob; De Vries, Fred
This list of frequently asked questions was composed on the basis of questions asked of the Educational Technology Expertise Centrum. The questions addessed are: Where can I find the IMS Learning Design Specification? What is meant by the phrase “Learning Design”? What is the IMS LD Specification
Judd, Kathleen S.; Young, Joan E.; Lesperance, Ann M.; Malone, John D.
This document provides a summary of Frequently Asked Questions (FAQs) on the treatment of anthrax disease caused by a wide-area release of Bacillus anthracis spores as an act bioterrorism. These FAQs are intended to provide the public health and medical community, as well as others, with guidance and communications to support the response and long-term recovery from an anthrax event.
Full Text Available Roland H Wenger,1,2 Vartan Kurtcuoglu,1,2 Carsten C Scholz,1,2 Hugo H Marti,3 David Hoogewijs1,2,4 1Institute of Physiology and Zurich Center for Human Physiology (ZIHP, University of Zurich, 2National Center of Competence in Research “Kidney.CH”, Zurich, Switzerland; 3Institute of Physiology and Pathophysiology, University of Heidelberg, Heidelberg, 4Institute of Physiology, University of Duisburg-Essen, Essen, Germany Abstract: “What is the O2 concentration in a normoxic cell culture incubator?” This and other frequently asked questions in hypoxia research will be answered in this review. Our intention is to give a simple introduction to the physics of gases that would be helpful for newcomers to the field of hypoxia research. We will provide background knowledge about questions often asked, but without straightforward answers. What is O2 concentration, and what is O2 partial pressure? What is normoxia, and what is hypoxia? How much O2 is experienced by a cell residing in a culture dish in vitro vs in a tissue in vivo? By the way, the O2 concentration in a normoxic incubator is 18.6%, rather than 20.9% or 20%, as commonly stated in research publications. And this is strictly only valid for incubators at sea level. Keywords: gas laws, hypoxia-inducible factor, Krogh tissue cylinder, oxygen diffusion, partial pressure, tissue oxygen levels
... You Ask? [cdc.gov]. Clinical Research at NHGRI Clinical researchers at the National Human Genome Research Institute (NHGRI) are developing advanced methods for studying the fundamental mechanisms of inherited and ...
... New Horizons and Research Patient Management Policy and Ethics Issues Quick Links for Patient Care Education All ... from discrimination by their health insurance provider or employer. GINA does not apply to long-term care, ...
... at www.fda.gov/findmammography . Do private insurance companies, Medicare and Medicaid pay for digital mammography exams, ... Map Nondiscrimination Website Policies U.S. Food and Drug Administration 10903 New Hampshire Avenue Silver Spring, MD 20993 ...
One stop shop for Federal Funding Accountability and Transparency Act (FFATA) questions. This frequently asked document will assist with Federal Funding Accountability and Transparency Act (FFATA) related questions.
... Vaccine Safety Frequently Asked Questions about Ventilator-associated Pneumonia Recommend on Facebook Tweet Share Compartir What is a Ventilator-associated Pneumonia (VAP)? Ventilator-associated pneumonia (VAP) is a lung ...
... Pan American Health Organization Frequently Asked Questions about Measles in the U.S. Language: English (US) Español (Spanish) ... I’ve been exposed to someone who has measles. What should I do? A: Immediately call your ...
Factsheet answering frequently asked questions about the U.S. Department of Energy's Alternative Fuel Transportation Program (the Program) that implements provisions of Titles III–V of the Energy Policy Act of 1992 (EPAct). Answers to questions that are frequently asked about the Program by managers of state government and alternative fuel provider fleets are provided in the factsheet.
As the presidential election of 2012 draws closer, Americans will witness a resurgence of references to the Electoral College in news reports. Here, "Looking at the Law" hopes to demystify the Electoral College, and refresh many social studies memories--just in time for the next election--with some frequently asked questions about electing the…
This article follows the author's previous piece on practical guidelines for the development of comprehensive competence-based education and training (Mulder, 2012). It is about the questions that have been and are still frequently asked in presentations, workshops and classes about the introduction
Kang, Dae Il; Kim, Kil Yoo; Park, Gee Yong
The FAQs(Frequently Asked Questions) in the Fire Probabilistic Safety Assessment(FPSA) are the issues occurred during performing the engineering evaluation based on NFPA-805. In this report, the background and resolutions are reviewed and described for 17 FAQs related to FPSA among 57 FAQs. The current FAQs related to FPSA are the issues concerning to NUREG/CR-6850, and are almost resolved but for the some FAQ, the current resolutions would be changed depending on the results of the future or on-going research. Among FAQs related to FPSA, best estimate approaches are suggested concerning to the conservative method of NUREG/CR-6850. If these best estimate solutions are used in the FPSA of nuclear power plants, realistic evaluation results of fire risk would be obtained
D'alò, G L; Zorzoli, E; Capanna, A; Gervasi, G; Terracciano, E; Zaratti, L; Franco, E
Routine mass immunization programs have contributed greatly to the control of infectious diseases and to the improvement of the health of populations. Over the last decades, the rise of antivaccination movements has threatened the advances made in this field to the point that vaccination coverage rates have decreased and outbreaks of vaccine-preventable diseases have resurfaced. One of the critical points of the immunization debate revolves around the level of risk attributable to vaccination, namely the possibility of experiencing serious and possibly irreversible adverse events. Unfortunately, the knowledge about adverse events, especially rare ones, is usually incomplete at best and the attribution of a causal relationship with vaccinations is subject to significant uncertainties. The aim of this paper is to provide a narrative review of seven rare or very rare adverse events: hypotonic hyporesponsive episode, multiple sclerosis, apnea in preterm newborns, Guillain-Barré syndrome, vasculitides, arthritis/ arthralgia, immune thrombocytopenic purpura. We have selected these adverse events based on our experience of questions asked by health care workers involved in vaccination services. Information on the chosen adverse events was retrieved from Medline using appropriate search terms. The review is in the form of questions and answers for each adverse event, with a view to providing useful and actionable concepts while not ignoring the uncertainties that remain. We also highlight in the conclusion possible future improvements to adverse event detection and assessment that could help identify individuals at higher risk against the probable future backdrop of ever-greater abandonment of compulsory vaccination policies.
This question-and-answer report provides answers in nontechnical language to frequently asked questions about the status of cleanup activities at Three Mile Island, Unit 2. The answers update information first prepared in 1981, shortly after the cleanup got under way. Since then, a variety of important developments in the cleanup has occurred. The information in the report should be read in conjunction with NUREG 1060, a discussion of increased occupational exposure estimates for the cleanup. The questions and answers in this report cover purpose and community involvement, decontamination of water and reactor, fuel removal, radwaste transport, environmental impact, social and economic effects, worker exposures and safety, radiation monitoring, potential for accidents, and schedule and funding
The document presents answers to frequently asked questions about plans for cleanup and decontamination activities at Three Mile Island, Unit 2. Answers to the questions asked are based on information in the NRC 'Draft Programmatic Environmental Impact Statement related to decontamination and disposal of radioactive wastes resulting from March 28, 1979, accident, Three Mile Island Nuclear Station, Unit 2' NUREG-0683
National Association for the Education of Homeless Children and Youth, 2009
This document provides answers to frequently asked questions on the McKinney-Vento Homeless Assistance Act and the education rights of children and youth in homeless situations. The answers are general responses based on federal statutes, regulations, and guidance; relevant case law; and best practices from across the country. While the National…
Duffield, Barbara; Julianelle, Patricia; Santos, Michael
This document provides answers to frequently asked questions on the McKinney-Vento Homeless Assistance Act and the education rights of children and youth in homeless situations, based on the amendments made by the Every Student Succeeds Act of 2015, which took effect on October 1, 2016. The answers are general responses based on federal statutes,…
... for psoriasis Anyone who has risk factors for Creutzfeldt-Jakob disease (CJD) or who has a blood relative with ... transmitting a transfusion-transmissible disease such as variant Creutzfeldt-Jakob disease (vCJD) - the human variety of the disease that ...
... IC Epidemiology (RICE) Study Boston Area Community Health (BACH) Survey ICA Pilot Research Program Funding Opportunities Clinical ... IC Epidemiology (RICE) Study Boston Area Community Health (BACH) Survey ICA Pilot Research Program Funding Opportunities Clinical ...
... SME Issue Briefs Compendium of Interventions ASMP/CDSMP Meta-Analysis Executive Summary Communication Campaigns Physical Activity. The Arthritis Pain Reliever. FAQs Campaign Materials Download General Campaign Materials Buenos días, artritis FAQs ...
... animals, and humans. It is caused by the Yersinia pestis bacteria. These bacteria are found in many areas ... other mammals that are infected with the bacterium Yersinia pestis . Fleas transmit the plague bacteria to humans and ...
Climate Change Finance with Adaptation Projects and Research in Africa (RFEI #11120029) ... in the team.” IDRC response: Please be advised that references to be included with each submission, as indicated in Part A- Instructions, Item 4, should be individuals who may be contacted by ... “What is meant by 'an inventory'?
... four years). What is a venous access device (port-a-cath)? A port-a-cath, or implantable venous access device (VAD), ... Grant Program World Bleeding Disorders Registry Treatment Safety Data Collection Ways to Give Ways to Give Give ...
... and clinical follow-up to a final diagnosis. Target Audience Women aged 40 to 64 years enrolled ... Word file Microsoft Excel file Audio/Video file Apple Quicktime file RealPlayer file Text file Zip Archive ...
... Questions Why are triglycerides important? The amount of triglycerides (or blood fats) in blood are one important barometer of metabolic health; high levels are associated with coronary heart disease, diabetes and fatty liver disease. Metabolism refers to the chemical process that converts the ...
Multitiered licensure structures can provide educators incentives to develop and improve their performance as they work toward advanced status. When working in tandem with compensation, career ladders, and ongoing professional learning policies, licensure can be a lever to promote educator development, advancement, and retention. Licensure…
Bonner, Kimberly B; Segal, David R
This paper is a response to Schumm's 2004 critique of Belkin's 2003 article, dealing with the "Don't Ask, Don't Tell" policy in the U.S. military. Schumm's critique specified four reasons for continuing to exclude homosexuals from military service: military effectiveness, sexual asymmetries, Christian soldiers' dilemma of "living a lie" and skewed opinions of policy makers and military elites. Each of these categories is analyzed and discussed.
On account of an increase of serogroup W135 meningococcal disease (M.D.) observed in Santiago, Chile, during last two years the medical community has experienced an avidity to update their knowledge about M.D. treatment and its prevention. In a queries and answers mode, the following topics on M.D. are presented: nasopharyngeal carriage and its importance, immunity and protection against the disease, reasons to choice ceftriaxone as the first line antibiotic in treatment, rationality and indications of chemoprophylaxis, fundamentals and advantages of conjugate vaccines, its indications, schedules, contraindications and decisions making in public health.
16 mai 2014 ... médicaments? • Non, le programme de recherche ne financera pas d'essais cliniques de vaccins ou de médicaments. Est-ce qu'une période de mise en œuvre du projet plus courte (<54 mois) serait considérée? .... doit posséder un statut juridique indépendant et être en mesure d'administrer des fonds.
... serotonin is made and is also a useful marker sometimes. Carcinoid Heart Disease How do carcinoids in the liver affect heart ... many cases it can be supplemented by other markers which should have been ... heart disease in patients with functioning tumors.In other neuroendocrine ...
... disease result in permanent brain damage leading to memory loss? I am a neurologist and I have ... and usually have jaundice (yellow eyes and skin color) and very abnormal lab results with respect to ...
... heat lamp, or the heat of a stove, fireplace, or radiator for warming. Affected areas are numb ... If you plan to use a wood stove, fireplace, or space heater, be extremely careful. Follow the ...
... some cases, but not always. There is no advantage to listing at more than one transplant center ... Subscribe to enews Follow Facebook Twitter LinkedIn YouTube Instagram Google+ Contact 700 N. 4th Street Richmond, VA ...
... at NHGRI About About the Institute Budget and Financial Information Divisions Director's Page How to Contact Us Institute ... will need Adobe Reader. What is pharmacogenomics? Pharmacogenomics uses information about a person's genetic makeup, or genome, to ...
... it is washed off. Clean clothes should be worn after treatment. In addition to the infested person, treatment also ... can be decontaminated by machine-washing in hot water and drying using the hot ... with scabies. After several treatments, he/she still has symptoms while I am ...
Mar 28, 2013 ... The call is open to research teams from academic institutions, private sector organizations with a research mandate, NGOs, civil society organizations, and research-based organizations. UN organizations may not apply as consortium members. CGIAR centres may apply as third parties, contracted by a ...
... chances are that others are thinking the same thing. Each child who isn't immunized gives highly contagious diseases one more chance to spread. As more people choose not to vaccinate their kids for one reason or another, outbreaks become more common, especially of ...
Why have we tried so hard to find the Higgs particle? How does the Higgs mechanism work? What is the difference in physics between strong evidence and a discovery? Why do physicists speak in terms of "sigmas"? Find out here! Why have we tried so hard to find the Higgs particle? Because it could be the answer to the question: how does Nature decide whether or not to assign mass to particles? All the fundamental particles making up matter – the electron, the quarks, etc. – have masses. Moreover, quantum physics requires that forces are also carried by particles. The W and Z particles that carry the weak force responsible for radioactivity must also have masses, whereas the photon, the carrier of the electromagnetic force, has no mass at all. This is the root of the “Higgs problem”: how to give masses to the fundamental particles and break the symmetry between the massive W and Z and the massless photon? Just assigning masses by hand...
Can IDRC provide help in identifying potential Canadian institution partners? • Unfortunately not. For ethical reasons in a competitive call, IDRC cannot assist applicant organizations and/or companies in identifying partners. We can, however, suggest some umbrella organizations that may provide helpful information.
... Search By Zipcode Search by State SELECT YOUR LANGUAGE Español (Spanish) 简体中文 (Traditional Chinese) 繁体中文 (Simplified Chinese) ... Hey Kids, Learn About Blood Sugar and Diabetes Teaching Gardens Teaching Gardens Recognition Teaching Gardens-See Our ...
... the vaccine, what should I do? What is Japanese encephalitis? Japanese encephalitis (JE) is a potentially severe ... cause inflammation of the brain (encephalitis). Where does Japanese encephalitis occur? JE occurs in Asia and parts ...
... P, Pancreatic Polypeptide and Atrial Naturetic Hormone (ANH) (fasting). The later (ANH) helps indicate development of carcinoid ... brief description of Creon and Pancrease, and the benefits of each? They are both pancreatic extracts of ...
May 16, 2014 ... 3) Co-principal application: a relevant local, district, or national level decision maker from the same country .... The role of the co-principal applicant includes similar responsibilities as those of the principal .... Considering the current political, economic and social instability in South Soudan, can international ...
Neff, Christopher L; Edgell, Luke R
We report on policy entrepreneurship by Servicemembers Legal Defense Network (SLDN) and how its legislative strategies used mini-windows of opportunity to shift Capitol Hill perspectives of Don't Ask, Don't Tell (DADT) from political plutonium to an emerging issue requiring a second look. Four phases in the legislative history of DADT are identified: radioactive, contested, emerging, and viable. In all, this article argues that SLDN's entrepreneurship focused on contesting congressional sensibilities to wait or defer on repeal, maintained that every discharge was damaging and transitioned toward a post-repeal mind set. Finally, we illustrate the importance of these transitions by comparing SLDN's 2004 estimated vote count for the introduction of the Military Readiness Enhancement Act with the final 2010 voting results on the Don't Ask, Don't Tell Repeal Act.
Rushmer, Rosemary; Shucksmith, Janet
In this paper the development of askFuse is used as a case study to illustrate contextual and system barriers to universities providing useful, usable and timely research evidence in response to local practice and policy partners' stated public health research needs. Entrenched systems (research excellence framework, academic career pathways,…
Rogers, Joy J.
Urges policymakers to examine and update their school system's child abuse reporting policy. Such policies must be adequate to help endangered children, protect their right to privacy, and avoid overprotection. Advises on ways to protect staff against unnecessary accusations and develop inservice training programs discussing child abuse, state…
The Department of Defense policy of excluding known homosexuals from military service is partially based on the assumption that homosexual service members pose a threat to the cohesion of a military unit...
Data from 115,052 active United States military personnel were analyzed to explore links between contact with gay people and attitudes about repealing "Don't Ask, Don't Tell." Results showed that prejudice against homosexuals significantly mediated the association between contact and supporting repeal of "Don't Ask, Don't Tell"; quality of contact in the military was a stronger predictor than other measures of contact. Quality and quantity of contact interacted: more contact quantity had opposing statistical effects on policy attitudes for people experiencing high versus low quality contact. Findings are discussed in terms of contact theory, the association between intergroup attitudes and policy preferences, and practical implications for situations in which groups' access to new positions or roles is limited, and hence contact opportunities are rare.
duty at the time of the study were serving when the DADT was enacted.9 It was recommended that the policy would be better utilized if Congress would...years, amid many changes in the military and society. Indeed, some of the U.S. military’s younger recruits during 2009 may have still been in diapers ...2004 survey looks closely at the three previous studies that utilized the same survey—that is, the 1994 study by LCDR Fred Cleveland and LT Mark Ohl
How widespread are workplace rules against discussing wages and salaries in the U.S.? And what are the core correlates of whether or not an employer prohibits or discourages this type of speech? Using a unique dataset that includes a measure of whether workers are prohibited or discouraged from discussing pay, this article investigates the prevalence of pay secrecy policies, and what worker- and workplace-level characteristics are associated with these rules. Key findings reveal that these policies are commonplace, despite being illegal, and that they are concentrated in more "coercive" rather than "enabling" organizations. These more coercive workplaces are disproportionately in the private sector, lack union representation, and have managers that are generally punitive in their approach and unaccommodating of employees. Findings also indicate that the greater discretion pay secrecy provides managers does not result in discriminatory application of these rules to women, racial/ethnic minorities, or immigrants. The article concludes with a call for data collection efforts that would allow researchers to analyze the consequences of this widespread managerial practice. Copyright © 2017 Elsevier Inc. All rights reserved.
... doing their job. Periodontists may also correct gum recession and cover up exposed root surfaces which can ... seeing a periodontist for a consultation is a great first step. There are a few ways to ...
... Compartir If a co-worker is diagnosed with scabies, what precautions must be taken? Should the office ... guidelines in case an employee is diagnosed with scabies. Can CDC provide the rules and regulations for ...
... spread lice? Can swimming spread lice? What are head lice? The head louse, or Pediculus humanus capitis , ... spread disease. Who is at risk for getting head lice? Head lice are found worldwide. In the ...
... medicine is best? Is mayonnaise effective for treating head lice? CDC does not have clear scientific evidence ... effective form of treatment. If the treatment for head lice doesn't seem to be working, does ...
... typhus still exists in places where climate, chronic poverty, and social customs or war and social upheaval ... Page last updated: September 24, 2013 Content source: Global Health – Division of Parasitic Diseases Email Recommend Tweet ...
... Global Activities Sub-Saharan Africa President’s Malaria Initiative (PMI) Kenya Malawi Tanzania Malaria in Pregnancy in Latin ... planning and implementation of the President’s Malaria Initiative (PMI), a $3 billion initiative to rapidly increase malaria ...
... should wear tightly fitting disposable surgical masks. If surgical masks are not available, even makeshift face coverings made of layers of cloth may be helpful in an emergency. People who have been exposed to a contagious ...
... Genome Project Fact Sheets Genetic Education Resources for Teachers Genomic Careers National DNA Day Online Education Kit Online Genetics Education Resources Smithsonian NHGRI Genome Exhibition Talking Glossary: English Talking Glossary: Español Issues Coverage & Reimbursement of Genetic ...
... Genome Project Fact Sheets Genetic Education Resources for Teachers Genomic Careers National DNA Day Online Education Kit Online Genetics Education Resources Smithsonian NHGRI Genome Exhibition Talking Glossary: English Talking Glossary: Español Issues Coverage & Reimbursement of Genetic ...
5) Can I submit the letter of affiliation in Spanish? 6) I have two research supervisors. Do both supervisors have to provide individual letters of approval or can they write a joint letter? 7) Can my research supervisor send the letter of approval directly to IDRC? 8) Do you accept scanned copies of transcripts sent by email, ...
... May Have Been Recently Exposed to Polonium-210 Strontium-90 (Sr-90) Radioisotope Brief Toxicology FAQs Uranium- ... top How will I know if food or water is safe? Following a radiation emergency, scientists will ...
... Treponema pallidum : a comparison of functional genomics, environmental adaptations, and pathogenic mechanisms. J Clin Invest 107: 651- ... This does not mean that the test is bad, only that it needs to be used correctly. ...
A healthy school environment is one of the keys to keeping young minds and bodies strong. In fact, a healthy school environment is one of eight core components in the Centers for Disease Control and Prevention (CDC) model “Healthy Youth! Coordinated
... was eradicated by a collaborative global vaccination programme led by the World Health Organization. The last known ... viruses). It could also be used to protect anyone else judged to have a high risk of ...
... Preventing Violence Pressure Washer Safety Trench Foot or Immersion Foot Emergency Wound Care Wound Management for Healthcare ... the skin. What should I do if I work in a hot environment? Pace yourself. If you ...
... at NHGRI About About the Institute Budget and Financial Information Divisions Director's Page How to Contact Us Institute ... located at: http://rarediseases.info.nih.gov/GARD . Users can also contact GARD's information specialists directly by e-mail, telephone, FAX, TTY ...
... of music in music therapy? Music therapists utilize music as a therapeutic tool; the genre and type of instrument is tailored to the individual and to the goals that are established between the client and the music therapist. Since music choice/usage is tailored to ...
... I be able to walk normally, or even exercise and run, after healing from bunion surgery? In ... Lead to Faster, Less Painful Recovery New techniques & custom surgical implants mean patients get back on their ...
... Management Resources Precision Medicine at NINR Research Highlights Data Science and Nursing Research Spotlight on End-of-Life ... Management Resources Precision Medicine at NINR Research Highlights Data Science and Nursing Research Spotlight on End-of-Life ...
What are the costs involved to submit a request under the Access to Information Act or Privacy Act? I have received my information from your Crown corporation and I am not satisfied with the results. What are my options?
... contact during play and other activities at home, school, and elsewhere (slumber parties, sports activities, camp, playground). Do not share clothing such as hats, scarves, coats, sports uniforms, hair ribbons, or barrettes. Do not share combs, ...
... to get insurance. www.covertheuninsured.org/stateguides Robert Wood Johnson Foundation www.rwjf.org These groups can ... received epidural anesthesia for their delivery. Because the anatomy of the spine is different, the epidural may ...
Do I have to use the IDRC forms to submit the financial report? Does IDRC require submission of receipts with financial reports? How long do we need to keep receipts for? How can .... The generally accepted accounting principles that are applicable in your jurisdiction must be used by your institution to administer the grant.
... equipment - posters 6. Can Ebola be transmitted sexually? Sexual transmission of the Ebola virus, from males to females, ... and research are needed on the risks of sexual transmission, and particularly on the prevalence of viable and ...
... does it mean to be above the legal limit for drinking? The legal limit for drinking is the alcohol level above which ... arrest or loss of a driver’s license). Legal limits are measured using either a blood alcohol test ...
... clump. Another example of post-translational modification of relevance to PSP is “transglutamination,” where the amino acid ... join? See our support group page here. The value of membership in a group of other people ...
... Treatment Care of Patients with Lymphedema, Elephantiasis or Hydrocele Publications Additional Resources Get Email Updates To receive ... prevented with appropriate skin hygiene. Men can develop hydrocele or swelling of the scrotum due to infection ...
... MRSA Mycobacterium abscessus Norovirus Pseudomonas aeruginosa Tracking CRPA Staphylococcus aureus Tuberculosis VISA / VRSA Vancomycin-resistant Enterococci (VRE) in Healthcare Settings Preventing HAIs Targeted Assessment for Prevention (TAP) TAP CAUTI Implementation Guide TAP CDI Implementation ...
... and our publications may not be used for advertising or endorsement purposes. NIMH does not provide specific ... MSC 9663 Bethesda, MD 20892-9663 Follow Us Facebook Twitter YouTube Google Plus NIMH Newsletter NIMH RSS ...
... not intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of ... questions regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something ...
... PHR can be accessed and edited through your mobile phone. My doctor gave me a Notice of Privacy ... to your information. You receive the notice the first time you visit a new healthcare provider, pharmacy, ...
... the Media Room Public Affairs News Releases Speeches Videos Publications National Observances Veterans Day Memorial Day Celebrating America's Freedoms Special Events Adaptive Sports Program Creative Arts Festival Golden Age Games Summer Sports Clinic Training - Exposure - Experience (TEE) Tournament ...
... the BG levels for women that are pregnant? Fasting 60-90 mg/dL (whole blood) 69-104 ... uterus or endometrium is reduced. What are the benefits of hormone replacement therapy? The benefits are decreased ...
Diffusion of innovation in mental health policy adoption: what should we ask about the quality of policy and the role of stakeholders in this process? Comment on "Cross-national diffusion of mental health policy".
In his recent study, Gordon Shen analyses a pertinent question facing the global mental health research and practice community today; that of how and why mental health policy is or is not adopted by national governments. This study identifies becoming a World Health Organization (WHO) member nation, and being in regional proximity to countries which have adopted a mental health policy as supportive of mental health policy adoption, but no support for its hypothesis that country recipients of higher levels of aid would have adopted a mental health policy due to conditionalities imposed on aid recipients by donors. Asking further questions of each may help to understand more not only about how and why mental health policies may be adopted, but also about the relevance and quality of implementation of these policies and the role of specific actors in achieving adoption and implementation of high quality mental health policies. © 2015 by Kerman University of Medical Sciences.
human rights , same-sex marriage, same-sex benefits, Personnel Policy, Gay Ban, Repeal of DADT, LGBT 16. PRICE CODE 17. SECURITY CLASSIFICATION OF...vote of 65–31 the Senate approved allowing gays and lesbians the right to serve openly in the military (Miscaro & Muskal, 2010). Subsequently, the... rights groups, businesses, contractors, religious groups, and civilians, that the change in policy would be treated with the utmost sensitivity and
Administration and, historically speaking, gay, lesbian, and bisexual (same- sex) behavior had not been tolerated in the military services. The issue...October 13, 2010: 1. 4 Usage of terms: Although the law and policy refer to ‘homosexuality’ and ‘ bisexuality ’ this report also refers, interchangeably, to...gays,” “lesbians,” and bisexuals . 5 “[H]e elicited approving whoops when he said he would sign an executive order to eliminate discrimination based
Of growing concern over Jehovah's Witnesses' (JWs) refusal of blood is the intrusion of the religious organisation into its members' personal decision making about medical care. The organisation currently may apply severe religious sanctions to JWs who opt for certain forms of blood-based treatment. While the doctrine may be maintained as the unchangeable "law of God", the autonomy of individual JW patients could still be protected by the organisation modifying its current policy so that it strictly adheres to the right of privacy regarding personal medical information. The author proposes that the controlling religious organisation adopt a "don't-ask-don't-tell" policy, which assures JWs that they would neither be asked nor compelled to reveal personal medical information, either to one another or to the church organisation. This would relieve patients of the fear of breach of medical confidentiality and ensure a truly autonomous decision on blood-based treatments without fear of organisational control or sanction. PMID:10635499
... Rockville, MD. http://www.ahrq.gov/patients-consumers/patient-involvement/ask-your-doctor/index.html Back to top Accessibility Disclaimers EEO Electronic Policies FOIA HHS Digital Strategy HHS Nondiscrimination Notice ...
Full Text Available ... Information Frequently asked questions Clinical Studies Publications Catalog Photos and Images Spanish Language Information Grants and Funding ... job openings visit HHS USAJobs Home >> NEI for Kids >> Ask a Scientist Video Series Listen All About ...
... Rehabilitation Medicine, Spinal Cord Injury Medicine, and/or Sports Medicine. | back to top | What kind of training do ... pediatrics, traumatic brain injury, spinal cord injury, and sports medicine. To become board certified in physical medicine and ...
Lin, S M; Smeltzer, C H; Thomas, C
This article is structured in a question/answer format based on interviews with Dr. Carolyn Hope Smeltzer and Salima Manji Lin of PricewaterhouseCoopers, Chicago, and Chuck Thomas of Hinshaw & Culbertson, Rockford. The questions come from CEO's, healthcare executives, and nurse executives at hospitals that are contemplating mergers or that have both succeeded and failed to merge their institutions. The experts share their knowledge.
Am I eligible? To be considered for the Cancer Prevention Fellowship Program (CPFP), you must meet eligibility criteria related to educational attainment, US citizenship/permanent residency status, and the duration of prior postdoctoral research experience. Refer to the Eligibility Requirements for details. How do I apply? You must apply through our online application process.
Environmental Science & Technology 2012, 46 (6), 3169-3176. REFERENCES 79 (72) Lollar, B. S.; Slater , G. F.; Ahad, J.; Sleep, B.; Spivack, J...3711. REFERENCES 80 (85) Morrill, P.; Lacrampe Couloume, G.; Slater , G. F.; Sleep, B. E.; Edwards, E.; McMaster, M. L.; Major, D...Sherwood Lollar, B., Quantifying Chlorinated Ethene Degradation During Reductive Dechlorination at Kelly Afb Using Stable Carbon Isotopes. Journal of
... group home on an annual excursion to a baseball game. Some sponsored trips carried out as part of a...) (1), requires a negotiated price, which implies an exchange of money. Thus, free service does not... that charter? A: Yes. Even though there are many baseball games over several months, the service is...
conduct their field research in one or more developing countries. Funds may be used to collect data and samples in the field, conduct interviews or surveys with local populations, and organize focus groups or workshops. Candidates must use findings of their field research to write their doctoral dissertation or thesis. You are ...
Hunter Myra S
Full Text Available Abstract The Women's Health Questionnaire (WHQ is a measure of mid-aged women's emotional and physical health. Since its publication in 1992 the WHQ has been widely used in multinational clinical trials, in epidemiological studies as well as in the evaluation of non-medical treatments. In particular the WHQ has been included as a quality of life measure in trials of hormonal preparations for peri and post menopausal women and in studies using a variety of preventative interventions for mid-aged and older women. The questionnaire was developed in English and standardised on a sample of women aged 45–65 years. It is reliable, has good concurrent validity and is sensitive to detecting change, and is available in 27 languages. The range of subscales included in the WHQ enable a detailed assessment of dimensions of emotional and physical health, such as depression, anxiety, sleep problems, somatic symptoms, with optional subscales for menstrual problems and sexual difficulties. The WHQ is the first measure to be included in the MAPI Research Institute's database, the International Health-related Quality of Life Outcomes Database (IQOD. Drawing upon data from international studies this project aims to produce reference values for cross-culturally valid, reliable and responsive quality of life instruments. In addition to this work, a revised shorter version of the WHQ is currently being developed.
... Links for Patient Care Education All About the Human Genome Project Fact Sheets Genetic Education Resources for Teachers Genomic ... Due to the success of large-scale biology projects such as the sequencing of the human genome, the suffix "-ome" is now being used in ...
Cason, Jana; Brannon, Janice A
As telehealth gains momentum as a service delivery model in the United States within the rehabilitation professions, regulatory and legal questions arise. This article examines the following questions: Is there a need to secure licenses in two states (i.e., where the practitioner resides, and where the client is located), before engaging in telehealth?Do state laws differ concerning if and how telehealth can occur?Do any states expressly disallow telehealth?Can services delivered through telehealth be billed the same way as services provided in-person?If practitioners fulfill the requirements to maintain licensure (e.g., continuing education obligations) in their state of residence, do they also need to fulfill the requirements to maintain licensure for the state in which the client resides?Will professional malpractice insurance cover services delivered through telehealth?Does a sole practitioner need to abide by HIPAA regulations?Responses to these questions are offered to raise awareness of the regulatory and legal implications associated with the use of a telehealth service delivery model within the professions of occupational therapy, physical therapy, speech-language pathology and audiology.
... Reconstruction Project Hanford Nuclear Weapons Facility The Hanford Thyroid Disease Study HTDS Guide Overview Hanford History How the ... 2000-2002 Public Involvement and Scientific Review About Thyroid Disease Research Team Video Excerpts Download Library Contact Us ...
... A prosthesis is basically an extension of your body. A standard prosthesis is made of conventional component parts that create ... limb to attain a proper, sound shape. Learn body positioning and strengthening to ... FOR A PROSTHESIS AND IT FEELS COMFORTABLE, WHAT HAPPENS NEXT? You ...
Baycan, T.; Nijkamp, P.
Urban planning has, in its rich history, often been reviewed from the perspective of different philosophical, ideological and methodological approaches by planners, architects and social scientists. In this paper, we aim to highlight the debate on urban planning in the context of planning history
Facebook Twitter Instagram YouTube About PHA Contact Join Careers Store My Account Donate Patients About PH Diagnosis Treatments Newly ... areas © 2017 Pulmonary Hypertension Association. All Rights Reserved. Facebook Twitter Instagram YouTube
... NLM resource. What is MedlinePlus? MedlinePlus is NLM's authoritative consumer health Web site. It includes consumer health ... systems to easily link users to MedlinePlus, an authoritative up-to-date health information resource for patients, ...
... or Giant Congenital Melanocytic Nevus are not hereditary, meaning you did not "pass it on" to your ... are the signs of melanoma? Changes in size, color, surface texture, pain, bleeding, or itching are all ...
... that satellite nevi rarely, if ever, develop melanoma. What are the signs of melanoma? Changes in size, color, surface texture, pain, bleeding, ... may arise deeper in a larger nevus. If melanoma is suspected, usually a small sample of the mole is removed and sent ... should be done about a congenital nevus? It's ...
General concepts and principles of Probabilistic Risk Assessment (PRA), describe how PRA can improve the bases of Agency decisions, and provide illustrations of how PRA has been used in risk estimation and in describing the uncertainty in decision making.
... (1) Can I be reimbursed for hazmat team salaries? Generally, no; only unbudgeted overtime and/or... is affected by a release? No, laying water lines doesn't fall within the definition of temporary...
... early treatment or management can prevent intellectual disability, physical disability, or even early death. How is the screen ... affected babies are at risk of intellectual disability, physical disabilities and even death if they are not diagnosed ...
Full Text Available As telehealth gains momentum as a service delivery model in the United States within the rehabilitation professions, regulatory and legal questions arise. This article examines the following questions:1. Is there a need to secure licenses in two states (i.e., where the practitioner resides, and where the client is located, before engaging in telehealth?2. Do state laws differ concerning if and how telehealth can occur?3. Do any states expressly disallow telehealth?4. Can services delivered through telehealth be billed the same way as services provided in-person?5. If practitioners fulfill the requirements to maintain licensure (e.g., continuing education obligations in their state of residence, do they also need to fulfill the requirements to maintain licensure for the state in which the client resides?6. Will professional malpractice insurance cover services delivered through telehealth?7. Does a sole practitioner need to abide by HIPAA regulations?Responses to these questions are offered to raise awareness of the regulatory and legal implications associated with the use of a telehealth service delivery model
The review of research proposals follows set procedures that do not involve feedback at this stage of your application. Candidates can check out the research currently being supported by. IDRC's programs and become familiar with the objectives of each award. Program staff may be contacted if there is a doubt concerning ...
... outcomes, mood changes (depending on the drug: depression, anxiety, paranoia, psychosis), and social or family problems caused or worsened by drugs. Repeated drug use can also lead to addiction . Studies show that the earlier a teen begins ...
Beck, Isabel L
Bringing Words to Life has enlivened the classrooms of hundreds of thousands of teachers. Responding to readers' success stories, practical questions, and requests for extended examples, this ideal volume builds on the groundbreaking work of Bringing Words to Life. The authors present additional tools, tips, and detailed explanations of such questions as which words to teach, when and how to teach them, and how to adapt instruction for English language learners. They provide specific instructional sequences, including assessments, for grades K-2, 3-5, 6-8, and 9-12, as well as interactive less
Provides answers to frequently asked questions regarding the Climate Leadership Awards, sponsored by EPA's Center for Corporate Climate Leadership with co-sponsorship from the Center for Climate and Energy Solutions and The Climate Registry.
Full Text Available Abstract Background In 2001 Health Canada responded to a series of Ontario court decisions by creating the Marihuana Medical Access Division (MMAD and the Marihuana Medical Access Regulations (MMAR. Although Health Canada has conducted a small number of stakeholder consultations, the federal government has never polled federally authorized cannabis patients. This study is an attempt to learn more about patient needs, challenges and experiences with the MMAD. Methods Launched in the spring of 2007, Quality of Service Assessment of Health Canada's Medical Cannabis Policy and Program pairs a 50 question online survey addressing the personal experiences of patients in the federal cannabis program with 25 semi-guided interviews. Data gathering for this study took place from April 2007 to Jan. 2008, eventually garnering survey responses from 100 federally-authorized users, which at the time represented about 5% of the patients enrolled in Health Canada's program. This paper presents the results of the survey portion of the study. Results 8% of respondents report getting their cannabis from Health Canada, while 66% grow it for themselves. >50% report that they frequent compassion clubs or dispensaries, which remain illegal and unregulated in Canada. 81% of patients would chose certified organic methods of cultivation; >90% state that not all strains are equally effective at relieving symptoms, and 97% would prefer to obtain cannabis from a source where multiple strains are available. Of the 48 patients polled that had tried the Health Canada cannabis supply, >75% rank it as either "1" or "2" on a scale of 1-10 (with "1" being "very poor", and 10 being "excellent". Discussion 72% of respondents report they are either "somewhat" or "totally unsatisfied" with Canada's medical cannabis program. These survey results and relevant court decisions suggest that the MMAR are not meeting the needs of most of the nation's medical cannabis patient community. It is
Hansen, Annette Skovsted
Motivation for the activity In academia the most important skill is to ask academically relevant and sound questions. This is not easy and students need to practice asking questions orally and in writing before they write research papers.......Motivation for the activity In academia the most important skill is to ask academically relevant and sound questions. This is not easy and students need to practice asking questions orally and in writing before they write research papers....
Full Text Available ... the media Pressroom Contacts Dustin Hays - Chief, Science Communication firstname.lastname@example.org Anna Harper - Media Relations email@example.com NEI Office of Communications (301)496-5248 Health Information Frequently asked questions ...
Full Text Available ... is to “conduct and support research, training, health information dissemination, and other programs with respect to blinding ... NEI Office of Communications (301)496-5248 Health Information Frequently asked questions Clinical Studies Publications Catalog Photos ...
Full Text Available ... visual function, preservation of sight, and the special health problems and requirements of the blind.” News & Events Events Calendar NEI Press Releases News from NEI Grantees Spokesperson bios ... Frequently asked questions Clinical Studies Publications Catalog ...
Ask Me Anything is a poetic text, aspiring to authenticate the particular poetic voice of its subject. This poetic subject is presented in the form of a 'Self' who is actively relating its interiority, reflexively and in a fractured manner, to the text Ask Me Anything.
... Join our e-newsletter! Resources What to Ask: Delirium Tools and Tips Under recognition of delirium is a major problem. It is important to ... questions you can ask your healthcare professional about delirium. What is delirium? What are its symptoms? How ...
Ask Nature is a site devoted to biomimicry, an interdisciplinary field in which practitioners study how animals and plants solve problems, and then use those solutions to develop better human technologies.
Assael, Marc J
Have you ever had a question that keeps persisting and for which you cannot find a clear answer? Is the question seemingly so "simple" that the problem is glossed over in most resources, or skipped entirely? CRC Press/Taylor and Francis is pleased to introduce Commonly Asked Questions in Thermodynamics, the first in a new series of books that address the questions that frequently arise in today's major scientific and technical disciplines. Designed for a wide audience, from students and researchers to practicing professionals in related areas, the books are organized in a user friend
Hoffman, Edward (Editor); Laufer, Alexander (Editor); Post, Todd (Editor); Brady, Jody Lannen (Editor)
The Academy of Program and Project Leadership (APPL) and ASK Magazine is presented. APPL is a research-based organization that serves NASA program and project managers, as well as project teams, at every level of development. In 1997, APPL was created from an earlier program to underscore the importance that NASA places on project management and project teams through a wide variety of products and services, including knowledge sharing, classroom and online courses, career development guidance, performance support, university partnerships, and advanced technology tools. ASK Magazine grew out of our Knowledge Sharing Initiative. The stories that appear in ASK are written by the 'best of the best' project managers, primarily from NASA, but also from other government agencies and industry. These stories contain genuine nuggets of knowledge and wisdom that are transferable across projects. Who better than a project manager to help another project manager address a critical issue on a project? Big projects, small projects-they're all here in ASK. APPL is one of our most exciting publications about project management.
Rutkowski, David J.; Prusinski, Ellen L.
The staff of the Center for Evaluation & Education Policy (CEEP) at Indiana University is often asked about how international large-scale assessments influence U.S. educational policy. This policy brief is designed to provide answers to some of the most frequently asked questions encountered by CEEP researchers concerning the three most popular…
Based on fieldwork in Mali this paper discusses the role of anthropology (and the anthropologist) in a large public health research project on children's health. In the uncertainty and disquiet that comes with the battle to combat and avoid diseases in a setting where poverty and abysmal diseases......, is the ability to move beyond even the best hidden assumptions and question our own questions, thereby enabling us to ask the right questions....
There is a widespread sentiment that panspermia is uninteresting is because it does not answer fundamental questions about the origin of life. The strongest version of panspermia asks entirely new questions. While barriers to the acceptance of panspermia are falling and evidence supporting it is accumulating, the mere possibility of panspermia unhinges the Darwinian account of evolutionary progress. The new theory removes an issue dividing science and religion, but it requires an amendment to the big bang theory.
Full Text Available ... the media Pressroom Contacts Dustin Hays - Chief, Science Communication firstname.lastname@example.org Kathryn DeMott, Media Relations Kathryn.DeMott@nih.gov NEI Office of Communications (301)496-5248 Health Information Frequently asked questions ...
de la Fuente, Luis; Toro, Carlos; Brugal, M Teresa; Vallejo, Fernando; Soriano, Vicente; Barrio, Gregorio; Ballesta, Rosario; Bravo, María J
To assess the validity of self-reported hepatitis B virus vaccination status in young heroin users. Cross-sectional study among 949 street-recruited young injection heroin users (IHUs) and non-injection heroin users (NIHUs) in Madrid, Barcelona and Seville. Face-to-face interviews and dried blood spot tested for anti-HBc and anti-HBs. The validity of self-reported vaccination status was assessed comparing with the serological status. The percentage of agreement with the kappa (kappa) statistic and the positive predictive value were calculated. The percentage of agreement between self-reported and serologic vaccination status was 51.9% overall, with little difference by city (53.1% in Barcelona, 49.0% in Madrid and 51.5% in Seville) or between IHUs (51.3%) and NIHUs (53.0%). All the kappa scores were lower than 0.1. The positive predictive value of self-reports was less than 25% in all categories analysed, except in the city of Barcelona (37%). Among those who indicated that they had been vaccinated, 31% were actually susceptible. In areas with a high prevalence of infection and rising coverage of vaccination the policy "don't ask, take a blood sample, give a dose of vaccine and try to schedule another visit" should be recommended in clinical practice.
Laufer, Alexander (Editor); Little, Terry (Editor); Davis, Marty (Editor); Simmons, Jessica (Editor); Margolies, Donald (Editor); Goshorn, Larry (Editor)
THIS ISSUE FEATURES A VISUAL DEPICTION OF THE ACADEMY of Program and Project Leadership (APPL). I imagine a variety of initial reactions to the drawing. One might be, "What is a cartoon doing in a magazine about project management?" Or perhaps, "Wow, nice colors-and fun." Another may be to closely search the image for signs, symbols and meaning. Still another, to read a new level of innovation and creativity into the picture. Undoubtedly, some readers will raise questions about the cost. Of course, any reaction is a sign of engagement. The stronger, the more energized the emotional and cognitive processing, the better. It is a sign of attention and interaction. For I've heard it said, "You only need to worry if they don t care one way or the other." So what is the point of the picture? To stimulate interest, raise questions, promote discussion, and maybe raise a smile.. .That, at least, was my initial reaction when I was introduced to the work of Nancy Hegedus, who helps to create these drawings for Root Learning Inc. At the NASA PM Conference, I was first shown the work Nancy had been doing with the help of Goddard s Knowledge Management Architect, Dr. Ed Rogers. I was immediately drawn into the power of visualization as a tool for more effective learning, communicating, and conveying complex knowledge concepts. We need new tools in today s world, where information and data overwhelms by sheer volume. There are articles, pamphlets, communications, and white papers-all aiming to convince and influence. Reactions to these tend to be either avoidance or mind-numbing, heavy-eyed consent; the message never registers or enters the soul. That s one of the reasons that APPL s Knowledge Sharing Initiative (KSI) has turned to storytelling as a memorable way of transfer- ring knowledge, inspiring imitation of best practices, and spurring reflection. ASK Magazine s recent fourth birthday marks an important milestone in APPL s continuing quest to provide ongoing support to
Survey of Active Duty Members Office of People Analytics The Defense Research, Surveys, and Statistics Center (RSSC), Office of People Analytics...Service, National Center for Health Statistics, and National Center for Education Statistics. In addition, private survey firms including RAND, WESTAT...conducted by ICF International on behalf of the Tricare Activity Management, had a 22% response rate weighted up to the full active duty military
RJ Salway; R Valenzuela; JM Shoenberger; WK Mallon; A Viccellio
Overcrowding in emergency departments is a problem in many countries around the world, including the United States and Chile. Emergency department (ED) overcrowding causes problems for patients and staff, including increased waiting times, increased ambulance diversion, increased length of stay, increased medical errors, increased patient mortality, and increased harm to hospitals due to financial losses. This article aims to describe the etiology of ED overcrowding and potential solutions th...
Akkaya, Hatice; Büke, Barış
This study aims to investigate average gestational week in which mothers feel their baby's movements for the first time, and the maternal-fetal factors affecting this time. A total of 423 pregnant women between 11 and 25 weeks of gestation were included in this prospective study. The patient cohort was divided into three subgroups according to the gestational week in which fetal movements were felt for the first time by the pregnant women. The women who felt the first movement before 25th percentile value constituted Group 1; between 25th and 75th percentile value constituted Group 2; and beyond 75th percentile value constituted Group 3. These three groups were then compared in terms of maternal age, parity, body mass index (BMI), tea and coffee consumption during pregnancy, smoking, educational status, accordance of mother to regular pregnancy follow-ups, placental site, and gender of the baby. These three groups were statistically and significantly different regarding the above mentioned determinants except for mothers' tea and coffee consumption, smoking, and gender of the baby (p perception of first fetal movements in both a positive and negative manner. Although it is hard to define an exact time for each individual, an approximate time according to our data can be given to a mother, which considers an affecting factor on the basis of average gestational week. Copyright © 2017. Published by Elsevier Taiwan LLC.
Might Authorize the Use of Force in Syria), LAWFARE BLOG, June 13, 2014 (arguing that plain text of 2002 Iraq AUMF may be reasonably construed to...Goldmith, A New Tactic to Avoid War Powers Resolution Time Limits?, LAWFARE BLOG, Sept. 2, 2014, at http://www.lawfareblog.com/2014/09/a-new-tactic-to...See Jack Goldsmith, Problems with the Obama Administration’s War Powers Resolution Theory, LAWFARE BLOG, June 16, 2011, at http://www.lawfareblog.com
... has been reported in 27 countries including Algeria, Austria, Bahrain, China, Egypt, France, Germany, Greece, Islamic Republic ... Middle East by working with the travel and tourism sectors and placing such materials at strategic locations ( ...
equipment at a higher-than-anticipated rate for missions in Afghanistan and elsewhere. As an example, Dunford cited a squadron slated to operate 10 planes ...superiority not only on land , at sea, in the air and in space, but also in cyberspace.” 11 Does the Administration’s budget proposal “fully repeal...military and pursues peace through strength, honoring the Federal Government’s first responsibility: to protect the Nation. It fully repeals the
US Department of Education, 2009
A severe form of influenza known as H1N1, commonly being called swine flu, has health officials around the world concerned. In the United States, the outbreak of H1N1 has prompted school closures and cancellation of school-related events. As the flu spreads, the Department of Education encourages school leaders, parents and students to know how to…
Harry L. Haney; William C. Siegel; Larry M. Bishop
This publication examines the most common situations noncorporate taxpayers. face when calculating Federal income tax on their timber holdings. It addresses aspects of each situation using a three-column format. The columns are: Type of Forest Activity, How to Qualify for Best Tax Treatment, and Reporting and Tax Forms. The responses are necessarily brief, and...
What to ask your doctor about epilepsy - adult; Seizures - what to ask your doctor - adult; Seizure - what to ask your doctor ... call to find more information about driving and epilepsy? What should I discuss with my boss at ...
A graph is a data structure that contains a set of nodes and a set of edges connecting these nodes. Nodes represent objects while edges model relationships among these objects. Graphs are used in various domains due to their ability to model complex relations among several objects. Given an input graph, the Frequent Subgraph Mining (FSM) task finds all subgraphs with frequencies exceeding a given threshold. FSM is crucial for graph analysis, and it is an essential building block in a variety of applications, such as graph clustering and indexing. FSM is computationally expensive, and its existing solutions are extremely slow. Consequently, these solutions are incapable of mining modern large graphs. This slowness is caused by the underlying approaches of these solutions which require finding and storing an excessive amount of subgraph matches. This dissertation proposes a scalable solution for FSM that avoids the limitations of previous work. This solution is composed of four components. The first component is a single-threaded technique which, for each candidate subgraph, needs to find only a minimal number of matches. The second component is a scalable parallel FSM technique that utilizes a novel two-phase approach. The first phase quickly builds an approximate search space, which is then used by the second phase to optimize and balance the workload of the FSM task. The third component focuses on accelerating frequency evaluation, which is a critical step in FSM. To do so, a machine learning model is employed to predict the type of each graph node, and accordingly, an optimized method is selected to evaluate that node. The fourth component focuses on mining dynamic graphs, such as social networks. To this end, an incremental index is maintained during the dynamic updates. Only this index is processed and updated for the majority of graph updates. Consequently, search space is significantly pruned and efficiency is improved. The empirical evaluation shows that the
What to ask your doctor about concussion - child; Mild brain injury - what to ask your doctor - child ... school people I should tell about my child's concussion? Can my child stay for a full day? ...
Jaundice - what to ask your doctor; What to ask your doctor about newborn jaundice ... What causes jaundice in a newborn child? How common is newborn jaundice? Will the jaundice harm my child? What are the ...
Full Text Available ... Ask a Scientist Video Series Listen All About Vision About the Eye Ask a Scientist Video Series ... Eye Health and Safety First Aid Tips Healthy Vision Tips Protective Eyewear Sports and Your Eyes Fun ...
... the Experts | Diphtheria, Tetanus, Pertussis Ask the Experts Diphtheria, Tetanus, Pertussis Ask the Experts Home Administering Vaccines ... infants have died. How many doses of pediatric diphtheria-tetanus-acellular pertussis (DTaP) vaccine does an infant ...
What to ask your doctor about epilepsy - child; Seizures - what to ask your doctor - child ... should I discuss with my child's teachers about epilepsy? Will my child need to take medicines during ...
Full Text Available ... to More Information Optical Illusions Printables Ask a Scientist Video Series Why can’t you see colors ... like these and more with our Ask a Scientist video series. Dr. Sheldon Miller answers questions about ...
What is the answer to inspiring sustainable behaviour? It starts with a question - or nineteen. With this simple and inspiring guide you'll learn how to ask for persistent, pervasive, and near-costless change by uncovering our hidden quirks, judgmental biases, and apparent irrationalities. The only change you'll need to make is how you ask.Businesses, larger or small, will soon have to cut costs and cut carbon, irrespective of the products they sell, or the services they perform. National government has structural policy and legislative needs, and local government has implementation and docum
... Migraine - what to ask your doctor; Tension-type headache - what to ask your doctor; Cluster headache - what to ask your doctor ... How can I tell if the headache I am having is dangerous? What are ... headache ? A migraine headache ? A cluster headache ? What medical ...
What to ask your doctor about dementia; Alzheimer disease - what to ask your doctor; Cognitive impairment - what to ask your doctor ... Alzheimer's Association. Dementia Care Practice Recommendations ... in a Home Setting. Updated 2009. Alz.org. www.alz.org/national/ ...
A problem that has been the focus of much recent research in privacy preserving data-mining is the frequent itemset hiding (FIH) problem. Identifying itemsets that appear together frequently in customer transactions is a common task in association rule mining. Organizations that share data with business partners may consider some of the frequent…
Full Text Available ... MSC 9300 Bethesda, MD 20892-9300 (Courier services use: Rockville, MD 20852) 301-451-2020 Research at ... Ask a Scientist Video Series Glossary The Visual System Your Eyes’ Natural Defenses Eye Health and Safety ... Ask a Scientist Video Series ...
Often teachers do not think through how to ask for what they want, or they are too busy to even try. That attitude can result in missed opportunities. And grumbling in the faculty lounge, rather than raising the issue with the boss, will not get the results. In this article, the author talks about the importance of the ask and describes how to ask…
Full Text Available ... Ask a Scientist Video Series Glossary The Visual System Your Eyes’ Natural Defenses Eye Health and Safety First Aid Tips Healthy Vision Tips Protective Eyewear Sports and Your Eyes Fun Stuff Cool Eye Tricks Links to More Information Optical Illusions Printables Ask a Scientist Video Series ...
What to ask your doctor about diarrhea - child; Loose stools - what to ask your doctor - child ... FOODS What foods can make my child's diarrhea worse? How should I prepare the foods for my child? If my child is still breastfeeding or bottle feeding, do I need to ...
Full Text Available ... Disease Education Program Glaucoma Education Program Low Vision Education Program ... Eye Ask a Scientist Video Series Glossary The Visual System Your Eyes’ Natural Defenses Eye Health and Safety ...
... your doctor; What to ask your doctor about cholesterol ... What is my cholesterol level? What should my cholesterol level be? What are HDL ("good") cholesterol and LDL ("bad") cholesterol? Does my cholesterol ...
Full Text Available ... search for current job openings visit HHS USAJobs Home >> NEI for Kids >> Ask a Scientist Video Series ... can see clearly from 25 feet away. NEI Home Contact Us A-Z Site Map NEI on ...
... Peripheral Artery Disease Venous Thromboembolism Aortic Aneurysm More Heart Failure Questions to Ask Your Doctor Updated:May 9, ... you? This content was last reviewed May 2017. Heart Failure • Home • About Heart Failure • Causes and Risks for ...
Full Text Available ... More Information Optical Illusions Printables Ask a Scientist Video Series Why can’t you see colors well ... Why does saltwater sting your eyes? Select a video below to get answers to questions like these ...
... page: //medlineplus.gov/ency/patientinstructions/000535.htm Taking medicines - what to ask your doctor To use the ... you are given. Get Information About Your New Medicine When your doctor prescribes a medicine, find out ...
What to ask your doctor about radiation therapy ... National Cancer Institute website. Radiation therapy and you: support for people with cancer. www.cancer.gov/publications/patient-education/radiationttherapy.pdf . Updated May 2007. Accessed December ...
Full Text Available ... Ask a Scientist Video Series Glossary The Visual System Your Eyes’ Natural Defenses Eye Health and Safety ... NEI Website Manager . Department of Health and Human Services | The National Institutes of Health | USA.gov NIH… ...
... Stuff Cool Eye Tricks Links to More Information Optical Illusions Printables Ask a Scientist Video Series Why can’ ... a scientist? Click to Watch What is an optical illusion? Click to Watch What is color blindness? Click ...
Full Text Available ... Stuff Cool Eye Tricks Links to More Information Optical Illusions Printables Ask a Scientist Video Series Why can’ ... a scientist? Click to Watch What is an optical illusion? Click to Watch What is color blindness? Click ...
Full Text Available ... Links to More Information Optical Illusions Printables Ask a Scientist Video Series Why can’t you see ... eyelids? Why does saltwater sting your eyes? Select a video below to get answers to questions like ...
This article distinguishes homonymy, homophony, homography and polysemy, and provides a list of the most frequent homonyms using corpus-derived data. For most of the homonyms, the most common meaning accounts for 90% or more of the total uses of the form. The pedagogical and research implications of these findings are discussed. (Contains 5…
Katz, Kenneth A
While U.S. courts consider a lawsuit alleging that the military's "don't ask, don't tell" policy violates the rights of gay and lesbian service members, the policy continues to jeopardize the health of those service members, the military, and the country at large.
Beynon Charlene E
Full Text Available Abstract Background Intimate partner violence (IPV against women is a serious public health issue and is associated with significant adverse health outcomes. The current study was undertaken to: 1 explore physicians’ and nurses’ experiences, both professional and personal, when asking about IPV; 2 determine the variations by discipline; and 3 identify implications for practice, workplace policy and curriculum development. Methods Physicians and nurses working in Ontario, Canada were randomly selected from recognized discipline-specific professional directories to complete a 43-item mailed survey about IPV, which included two open-ended questions about barriers and facilitators to asking about IPV. Text from the open-ended questions was transcribed and analyzed using inductive content analysis. In addition, frequencies were calculated for commonly described categories and the Fisher’s Exact Test was performed to determine statistical significance when examining nurse/physician differences. Results Of the 931 respondents who completed the survey, 769 (527 nurses, 238 physicians, four whose discipline was not stated provided written responses to the open-ended questions. Overall, the top barriers to asking about IPV were lack of time, behaviours attributed to women living with abuse, lack of training, language/cultural practices and partner presence. The most frequently reported facilitators were training, community resources and professional tools/protocols/policies. The need for additional training was a concern described by both groups, yet more so by nurses. There were statistically significant differences between nurses and physicians regarding both barriers and facilitators, most likely related to differences in role expectations and work environments. Conclusions This research provides new insights into the complexities of IPV inquiry and the inter-relationships among barriers and facilitators faced by physicians and nurses. The
Fischer, Lauren H; Bajaj, Anureet K
Women are less likely to reach top-level leadership positions, and more likely to leave academic positions, than men, and are likely to earn less money than men. Women are also less likely to initiate a negotiation-a process that is crucial for professional advancement. This reluctance to ask hinders their advancement and can have long-lasting consequences-both financial and professional. The reasons that women do not ask are multifactorial. In this article, we will explore reasons why women are less likely to negotiate, the barriers they face when they do, and strategies that women can apply to improve their negotiation skills.
Hammond, Cynthia; Ackerman-Rainville, Rosemary
Students are in the best position to recognise the qualities of effective nurse educators. With this in mind, we asked students on the Bachelor of Science in Nursing (BScN) course what makes a good teacher in the clinical practice setting.
Full Text Available ... Jobs Fellowships NEI Summer Intern Program Diversity In Vision Research & Ophthalmology (DIVRO) Student Training Programs To search for current job openings visit HHS USAJobs Home >> NEI for Kids >> Ask a Scientist Video Series Listen All About Vision About ...
Full Text Available ... other programs with respect to blinding eye diseases, visual disorders, mechanisms of visual function, preservation of sight, and the special health ... Eye Ask a Scientist Video Series Glossary The Visual System Your Eyes’ Natural Defenses Eye Health and ...
Abercrombie, Denice; Cochran, Mathilda; Mims, Margaret
Presents a collection of questions that fifth-grade students asked about African artwork and answers provided by staff from the Museum of Fine Arts in Houston, Texas. Observes that students' interest in important visual aspects of the art creates lead-ins to more detailed discussions of West African art and culture. (DSK)
Squires, Katie E.; Bickel, Alyssa
Children with autism have impairments in communication that make it difficult for them to acquire the ability to ask appropriate wh- questions. This is a very important skill, and one that clinicians often do not know how to target. Search terms were entered into several databases to locate studies published in peer-reviewed journals. The studies…
Shows how writing news stories about fairy tale characters enlivens student writing classes. Suggests assignments for creating a fairy tale newspaper with news stories, obituaries, editorials and letters to the editor, advice columns ("Ask Mother Goose"), weddings and social events, sports news, and advertisements. (RL)
Introduction. Failure to find information is common. An exploratory analysis of cases when family members or friends were asked for information can provide better understanding of when, how and why interpersonal information seeking within a close network of individuals fails. Method. A sample of utterances (in form of "I asked my mum, but") was…
Full Text Available Salah satu keunggulan dari sebuah lembaga/unit pelayanan adalah seberapa cepat dan akurat dalam menangani keluhan pelanggan. Keluhan yang disampaikan pelanggan umumnya memiliki kesamaan dengan keluhan-keluhan sebelumnya, sehingga solusi dari keluhan baru dapat didasarkan pada solusi yang diberikan pada keluhan lama. Vector Space Model (VSM merupakan salah satu model yang digunakan untuk mengetahui kemiripan dokumen, yang digunakan dalam membangkitkan FAQ otomatis. Pembobotan term dilakukan dengan teknik Term Frequency-Inverse Document Frequency (TF-IDF. Kombinasi notasi TF-IDF yang dibandingkan adalah TF-IDF itu sendiri, modifikasi logaritmik TF dan modifikasi logaritmik IDF. Similarity measure yang digunakan adalah cosine similarity. Hasil dari penelitian ini adalah algoritma VSM dengan pembobotan TF-IDF dapat digunakan untuk membangkitkan FAQ otomatis dan solusi yang relevan. Berdasarkan hasil perhitungan accuracy pada masing- masing percobaan dapat disimpulkan bahwa pada threshold 0.5, kombinasi notasi TF-IDF yang memiliki nilai rata-rata accuracy dan precision tertinggi adalah modifikasi pertama, yaitu masing-masing sebesar 62.09% dan 55.15%. Sedangkan untuk threshold 0.65 yang memiliki nilai rata-rata accuracy dan precision tertinggi adalah TF-IDF, yaitu masing-masing sebesar 83.18% dan 68.35%. Selain itu percobaan dengan menggunakan 171 data, TF-IDF dan threshold 0.65 dapat membangkitkan 27 FAQ, yaitu dengan persentase 70.37% relevan.
satisfaction , that are not reflected in employment rates or earnings. Further research using other kinds of data, such as surveys and interviews, could help...the Post-Activation Civilian Earnings of Reservists,” Labour Economics, 2012. • Michael Hansen and Shanthi Nataraj, Expectations About Civilian...possibility that the program improved participants’ nonmonetary job outcomes, such as greater job satisfaction or better working conditions. Despite
National Institute of Mental Health (NIMH), 2009
Research shows that half of all lifetime cases of mental illness begin by age 14. Scientists are discovering that changes in the body leading to mental illness may start much earlier, before any symptoms appear. Through greater understanding of when and how fast specific areas of children's brains develop, we are learning more about the early…
Cameron, W. Scott
This paper presents an interview with Scott Cameron who is the Capital Systems Manager for the Food and Beverage Global Business Unit of Procter and Gamble. He has been managing capital projects and mentoring other project managers for the past 20 years at Procter and Gamble within its Beauty Care, Health Care, Food and Beverage, and Fabric and Home Care Businesses. Scott also has been an Academy Sharing Knowledge (ASK) feature writer since Volume One.
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Department of Justice, Washington, DC. Civil Rights Div.
This publication provides answers to 30 frequently asked questions about child care centers and the Americans with Disabilities Act (ADA). Questions are grouped into the following categories: coverage, general information, personal services, issues regarding specific disabilities, making the child-care facility accessible, tax provisions, the…
This guidebook addresses the primary requirements of the Alternative Fuel Transportation Program to help state and alternative fuel provider fleets comply with the Energy Policy Act via the Standard Compliance option. It also addresses the topics that covered fleets ask about most frequently.
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Although frequent sequential pattern mining has an important role in many data mining tasks, however, it often generates a large number of sequential patterns, which reduces its efficiency and effectiveness. For many applications mining all the frequent sequential patterns is not necessary, and mining frequent Max, or Closed sequential patterns will provide the same amount of information. Comparing to frequent sequential pattern mining, frequent Max, or Closed sequential pattern mining g...
Wells, Amy Stuart; Roda, Allison
This chapter examines how the larger political context and policies enacted at different points in American history have affected the questions education researchers asked and answered. The authors argue that while education researchers are often quick to consider how their research should shape policy, they are less likely to contemplate the…
What to ask your doctor about ear tube surgery; Tympanostomy - what to ask your doctor; Myringotomy - what ... other treatments? What are the risks of the surgery? Is it safe to wait before getting ear ...
... Abuse Treatment: Know What To Ask » Introduction Seeking Drug Abuse Treatment: Know What To Ask Email Facebook Twitter Introduction The goal of drug abuse treatment is to stop drug use and allow ...
What to ask your doctor about high blood pressure; Hypertension - what to ask your doctor ... problems? What medicines am I taking to treat high blood pressure? Do they have any side effects? What should ...
What to ask your health care provider about diarrhea - adult; Loose stools - what to ask your health ... medicines, vitamins, herbs, or supplements I take cause diarrhea? Should I stop taking any of them? What ...
Rabel, Antoinette; Leitman, Susan F; Miller, Jeffery L
The study aims to review a condition defined by the desire to consume ice in order to satisfy an addictive-like compulsion, rather than for purposes of hydration or pain relief. This condition is called ice pica, or pagophagia. Associations between ice pica and iron deficiency, suggestions for clinical screening of at risk populations, and recommendations for treatment and follow-up care are provided. An extensive literature review of original research articles, reviews, clinical practice manuscripts, and scientific publications on pica and pagophagia. A compulsion or craving for the consumption of ice is often overlooked in clinical practice. It is therefore important for clinicians to include ice pica as part of the review of systems for certain patient populations. Ice pica is frequently associated with iron deficiency, and iron supplementation is an effective therapy in most cases. Knowledge gained from screening for ice pica can generate valuable patient information and lead to the diagnosis and treatment of iron deficiency. The populations at risk include young women and blood donors of either sex. Published 2015. This article is a U.S. Government work and is in the public domain in the USA.
I will present the results from a qualitative study of the values and norms for thinking about science in academic astronomy, as seen through astronomers’ beliefs about departmental speech events. In-depth interviews were carried out with 12 graduate students and 9 faculty members from a prominent astronomy department at a large, public university. Interviewees were asked about a variety of speaking events in their department. The speaking events chosen were those at which: (1) graduate students could be presenters and/or ask questions, and (2) presenters spoke about science research to an audience of academic peers. This included Coffee Hour, Journal Club, research seminars, Colloquium, and dissertation defense talks. These events are part of the socialization of students into "acting like an astronomer.” Socialization is a process by which novices learn the rules (can and can't do), norms (should and shouldn't do), and values of a culture. The values of astronomy culture are encoded within the rules for participation in these events and the assumptions that audience members make about speakers. When these values contradict each other speakers face the dilemma of choosing between conflicting behaviors. One of the central dilemmas that arose in this study was that of whether or not to ask a question during a talk. Both graduate students and faculty members wanted students to speak up more often. However, students had conflicting worries - of voicing a question and it being a "stupid question” vs. having remained silent if it turned out to have been a "good question.” I will argue that this anxiety is a product of academic culture and not an indicator of individual failure, and discuss a number of factors that influence this situation, such as the perceived goals of each event, and astronomers’ beliefs about intelligence and learning.
Campagna, Andrea; Pagh, Rasmus
concerning finding frequent patterns in event sequences. Our motivation comes from working with a data set of 2 million RFID readings from baggage trolleys at Copenhagen Airport. The question of finding frequent passenger movement patterns is mapped to the above problem. We report on experimental findings...
to status. You could not ask what a person’s sexual status was, but if they displayed or talked about behaviors demonstrating a propensity to engage in... homophobic than the policy in place when President Clinton took office. Second, they think that President Clinton should get the credit for this change... behaviors are seen through the prism of race or sexual orientation. This potentially makes members of racial and sexual minorities targets of
Zimek, Arthur; Assent, Ira; Vreeken, Jilles
Discovering clusters in subspaces, or subspace clustering and related clustering paradigms, is a research field where we find many frequent pattern mining related influences. In fact, as the first algorithms for subspace clustering were based on frequent pattern mining algorithms, it is fair to say...... that frequent pattern mining was at the cradle of subspace clustering—yet, it quickly developed into an independent research field. In this chapter, we discuss how frequent pattern mining algorithms have been extended and generalized towards the discovery of local clusters in high-dimensional data....... In particular, we discuss several example algorithms for subspace clustering or projected clustering as well as point out recent research questions and open topics in this area relevant to researchers in either clustering or pattern mining...
Tompkins, Olga S; Randolph, Susan A; Ostendorf, Judith S
Bagshaw (2004) notes "the modern commercial aircraft cabin is maintained with adequate environmental control for the comfort of most healthy individuals" (p. 417). Occupational health nurses frequently deal with a population that may include unhealthy individuals or those with pre-existing conditions. It is critical for occupational health nurses to stay current with major hazards faced by frequent flyer business travelers to assist in identifying and preventing adverse health effects associated with these exposures.
Did you learn anything today? But not my mother. “Izzy,” she would say, “did you ask a good question today?” That difference — asking good questions — made me become a scientist.” And what kind of scientist did he become? He was. Isidor Isaac Rabi, who worked in the Physics department in. Columbia University, USA.
Saif Ur Rehman
Full Text Available Due to rapid development of the Internet technology and new scientific advances, the number of applications that model the data as graphs increases, because graphs have highly expressive power to model a complicated structure. Graph mining is a well-explored area of research which is gaining popularity in the data mining community. A graph is a general model to represent data and has been used in many domains such as cheminformatics, web information management system, computer network, and bioinformatics, to name a few. In graph mining the frequent subgraph discovery is a challenging task. Frequent subgraph mining is concerned with discovery of those subgraphs from graph dataset which have frequent or multiple instances within the given graph dataset. In the literature a large number of frequent subgraph mining algorithms have been proposed; these included FSG, AGM, gSpan, CloseGraph, SPIN, Gaston, and Mofa. The objective of this research work is to perform quantitative comparison of the above listed techniques. The performances of these techniques have been evaluated through a number of experiments based on three different state-of-the-art graph datasets. This novel work will provide base for anyone who is working to design a new frequent subgraph discovery technique.
Works cited in six forensic psychology journals published 2008-2010 were counted to identify the most frequently cited journals. The sample of works cited (N = 21,776) was not a definitive ranked list of important journals in forensic psychology, but was large enough to indicate high-impact journals. The list of frequently cited publications included more general psychiatry and psychology journals than titles specific to forensic psychology. The implications of the proportion of general versus specific titles for collections supporting research in forensic psychology were discussed.
Hansen, Per Svejstrup
This paper investigates the effect of uncertainty on a single firm's pricing behaviour in a dynamic menu cost model that results in (S,s)-rules where the price is fixed inside a band. It will be demonstrated that even though the band of inaction widens in response to increased uncertainty......, the price may be changed more frequent in the short run, and in the long run it definitely will. Hence, observing frequent price changes is not necessarily inconsistent with a firm operating under menu costs. This paper relies on an article by Dixit (1991), (Review of Economic studies, 58, 141...
Campagna, Andrea; Pagh, Rasmus
concerning finding frequent patterns in event sequences. Our motivation comes from working with a data set of 2 million RFID readings from baggage trolleys at Copenhagen Airport. The question of finding frequent passenger movement patterns is mapped to the above problem. We report on experimental findings......Given a directed acyclic graph with labeled vertices, we consider the problem of finding the most common label sequences (``traces'') among all paths in the graph (of some maximum length $m$). Since the number of paths can be huge, we propose novel algorithms whose time complexity depends only...
Bristowe, Katherine; Patrick, Peter L
To explore use of 'Invitations to Ask Questions' (IAQs) by plastic surgeons in outpatient consultations, and consider how type of IAQ impacts on patients' responses to, and recollection of, IAQs. Descriptive study: 63 patients were audio recorded in consultation with 5 plastic surgeons, and completed a brief questionnaire immediately after the consultation. Consultation transcripts were analyzed using inductive qualitative methods of Discourse Analysis and compared with questionnaire findings. A taxonomy of IAQs was developed, including three types of IAQ (Overt, Covert, and Borderline). Overt IAQs were rarely identified, and almost all IAQs occurred in the closing stages of the consultation. However, when an overt IAQ was used, patients always recollected being asked if they had any questions after the consultation. Patients are rarely explicitly offered the opportunity to ask questions. When this does occur, it is often in the closing stages of the consultation. Clinicians should openly encourage patients to ask questions frequently throughout the consultation, and be mindful that subtle differences in construction of these utterances may impact upon interpretation. Clear communication, of message and intention, is essential in clinical encounters to minimize misunderstanding, misinterpretation, or missed opportunities for patients to raise concerns. Copyright © 2014. Published by Elsevier Ireland Ltd.
Wiendels, Natalie Janette
This thesis describes the results of a large questionnaire-based study on the epidemiology of chronic frequent headache (CFH) in the Dutch adult population. It also includes information on triptan (over)use from the Drug Information Project (GIP database) and the results of a withdrawal trial in
Tye-Murray, Nancy; Spehar, Brent; Sommers, Mitchell; Barcroft, Joe
Purpose: Individuals with hearing loss engage in auditory training to improve their speech recognition. They typically practice listening to utterances spoken by unfamiliar talkers but never to utterances spoken by their most frequent communication partner (FCP)--speech they most likely desire to recognize--under the assumption that familiarity…
Katz, Steven J
The objective of this study was to analyze the use of an Ask-the-Rheumatologist website service. All questions submitted were analyzed for gender, geographic location, topic area, disease, appropriateness, personal experience, and whether the answer is found elsewhere on the hosting website. The number of total visits and their geographic location was determined. The web service was visited 7985 times. Two hundred twenty-seven questions were submitted, with a majority related to personal experience and inflammatory rheumatic disease. One hundred six questions did not have answers available elsewhere on the website. Seventy questions were deemed inappropriate. Ask-the-Rheumatologist was visited frequently, demonstrating an innovative method of knowledge-transfer between health professionals, patients, and the general public.
... Families - Vietnamese Substance Abuse Treatment For Children And Adolescents: Questions To Ask No. 41; Reviewed July 2013 Many children and adolescents use alcohol and other drugs. Some develop serious ...
... Questions to Ask Your Doctor - Implantable Cardioverter Defibrillator (ICD) Updated:Dec 21,2016 Implantable cardioverter defibrillators are ... are the benefits versus the limitations of the ICD? What is the general prognosis and how might ...
Silva Aycaguer, L C
Several errors that are frequently present in clinical research are listed, discussed and illustrated. A distinction is made between what can be considered an "error" arising from ignorance or neglect, from what stems from a lack of integrity of researchers, although it is recognized and documented that it is not easy to establish when we are in a case and when in another. The work does not intend to make an exhaustive inventory of such problems, but focuses on those that, while frequent, are usually less evident or less marked in the various lists that have been published with this type of problems. It has been a decision to develop in detail the examples that illustrate the problems identified, instead of making a list of errors accompanied by an epidermal description of their characteristics. Copyright © 2018 Elsevier España, S.L.U. y SEMICYUC. All rights reserved.
Arizaga, Raúl L; Cristalli, Diana O; Golimstok, Angel; Saredo, Gustavo
In the present chapter, that is part of a more comprehensive work performed by the Argentine Consortium for Dementia Study - Consortium Argentino para el Estudio de la Demencia (CAED), we describe the most frequent forms of beginning for the four more prevalent types of dementia: Alzheimer's disease, dementia with Lewy bodies, vascular dementia and frontotemporal dementia). Despite this, it must be kept in mind, that frequently the clinical presentation is not typical and the diagnostic impression at the disease's beginning is controversial comparing it with the etiological diagnosis reached when the dementia is definitively installed. This issue must be considered when the initial impression is given to the patient and/or relatives. It must be clarified, in this instance, that this impression is based in statistical data of ways of presentation, but the definitive diagnosis could be different according to the dementia evolution.
Bayir, Murat Ali; Toroslu, Ismail Hakki; Cosar, Ahmet; Fidan, Guven
Web usage mining is a type of web mining, which exploits data mining techniques to discover valuable information from navigation behavior of World Wide Web users. As in classical data mining, data preparation and pattern discovery are the main issues in web usage mining. The first phase of web usage mining is the data processing phase, which includes the session reconstruction operation from server logs. Session reconstruction success directly affects the quality of the frequent patterns disc...
Full Text Available A frequently forgotten old malady called botulism has been recognized for more than a century. This ailment occurs worldwide, afflicts human of all age groups from infants to elderly and affects Oriental people more often in several regions of China. Occurrence in Taiwan is uncommon, and therefore, it is often overlooked. The outbreaks of human botulism in various regions of the world, the clinical types, the molecular mechanisms, and the electrophysiologic findings will be highlighted.
Seguin, Jade; Osmanlliu, Esli; Zhang, Xun; Clavel, Virginie; Eisman, Harley; Rodrigues, Robert; Oskoui, Maryam
Emergency department (ED) crowding is associated with increased morbidity and mortality. Its etiology is multifactorial, and frequent ED use (defined as more or equal to five visits per year) is a major contributor to high patient volumes. Our primary objective is to characterize the frequent user population. Our secondary objective is to examine risk factors for frequent emergency use. We conducted a retrospective cohort study of pediatric emergency department (PED) visits at the Montreal Children's Hospital using the Système Informatique Urgence (SIURGE), electronic medical record database. We analysed the relation between patient's characteristics and the number of PED visits over a 1-year period following the index visit. Patients totalling 52,088 accounted for 94,155 visits. Of those, 2,474 (4.7%) patients had five and more recurrent visits and accounted for 16.6% (15,612 visits) of the total PED visits. Lower level of acuity at index visit (odds ratio [OR] 0.85) was associated with a lower number of recurrent visits. Lower socioeconomic status (social deprivation index OR 1.09, material deprivation index OR 1.08) was associated with a higher number of recurrent visits. Asthma (OR 1.57); infectious ear, nose, and sinus disorders (OR 1.33); and other respiratory disorders (OR 1.56) were independently associated with a higher incidence of a recurrent visit within the year following the first visit. Our study is the first Canadian study to assess risk factors of frequent pediatric emergency use. The identified risk factors and diagnoses highlight the need for future evidence-based, targeted innovative research evaluating strategies to minimize ED crowding, to improve health outcomes and to improve patient satisfaction.
Elvira A. Baranova
Full Text Available Children’s questions are an indicator of active cognitive perception of reality. Questions but not answers are relevant in revealing a child’s mental life, consciousness and thinking. The lack of question-asking skills can hinder learning, searching and exploration in children. To determine in 7- and 8-year-old school children the common and variable peculiarities of designing a search process for necessary information concerning an unknown object by volitionally formulated questions, as well as the dynamics of the questioning process throughout a school year. The study was based on an experimental methodology, codenamed Guess what there is in the box, and was conducted in four schools in Cheboksary. The sample comprised 158 primary school first-graders who took part in a confirmatory experiment twice, once in September and once in May. The research showed that 96.3% of the questions asked were search questions. Only 30% of the first-graders initiated their searching activities of their own will without having to resort to the given search algorithm, while 70% did not begin asking questions without outside stimulation. The analysis of the dynamics of children’s question-asking behavior exhibited a tendency to decrease in a number of questions asked over the course of the school year. Primary school children need psychological and pedagogical scaffolding aimed at developing a question-asking behavior as a form of cognitive activity to achieve a possible age potential in development.
Randolph, Susan A
The development of policies and procedures is an integral part of the occupational health nurse's role. Policies and procedures serve as the foundation for the occupational health service and are based on its vision, mission, culture, and values. The design and layout selected for the policies and procedures should be simple, consistent, and easy to use. The same format should be used for all existing and new policies and procedures. Policies and procedures should be reviewed periodically based on a specified time frame (i.e., annually). However, some policies may require a more frequent review if they involve rapidly changing external standards, ethical issues, or emerging exposures.
Posamentier, Alfred S (Steven); Germain-Williams, Terri L (Lynn); Paris, Elaine S; Lehmann, Ingmar H (Horst)
100 ways to get students hooked on math! That one question got you stumped? Or maybe you have the answer, but it's not all that compelling. Al Posamentier and his coauthors to the rescue with this handy reference containing fun answers to students'100 most frequently asked math questions. Even if you already have the answers, Al's explanations are certain to keep kids hooked. The big benefits? You'll discover high-interest ways to Teach to the Common Core's math content standards Promote inquiry and process in mathematical thinking Build procedural skills and conceptual understanding Encourage
Strandberg-Larsen, Katrine; Andersen, Anne-Marie Nybo; Olsen, Jørn
OBJECTIVE: To study if pregnant women give the same answers to questions on frequency and timing of binge drinking when asked more than once during and after pregnancy. DESIGN: Cohort study.Setting:The Danish National Birth Cohort. SUBJECTS: The study is based on 76 307 pregnant women with repeat....... CONCLUSIONS: Self-reported information on binge drinking is more frequently under-reported when the recall period is long. To improve the validity of data on binge drinking, future birth cohorts should obtain information several times during pregnancy....
Berard, Aaron V; Cain, Matthew S; Watanabe, Takeo; Sasaki, Yuka
Playing certain types of video games for a long time can improve a wide range of mental processes, from visual acuity to cognitive control. Frequent gamers have also displayed generalized improvements in perceptual learning. In the Texture Discrimination Task (TDT), a widely used perceptual learning paradigm, participants report the orientation of a target embedded in a field of lines and demonstrate robust over-night improvement. However, changing the orientation of the background lines midway through TDT training interferes with overnight improvements in overall performance on TDT. Interestingly, prior research has suggested that this effect will not occur if a one-hour break is allowed in between the changes. These results have suggested that after training is over, it may take some time for learning to become stabilized and resilient against interference. Here, we tested whether frequent gamers have faster stabilization of perceptual learning compared to non-gamers and examined the effect of daily video game playing on interference of training of TDT with one background orientation on perceptual learning of TDT with a different background orientation. As a result, we found that non-gamers showed overnight performance improvement only on one background orientation, replicating previous results with the interference in TDT. In contrast, frequent gamers demonstrated overnight improvements in performance with both background orientations, suggesting that they are better able to overcome interference in perceptual learning. This resistance to interference suggests that video game playing not only enhances the amplitude and speed of perceptual learning but also leads to faster and/or more robust stabilization of perceptual learning.
Aaron V Berard
Full Text Available Playing certain types of video games for a long time can improve a wide range of mental processes, from visual acuity to cognitive control. Frequent gamers have also displayed generalized improvements in perceptual learning. In the Texture Discrimination Task (TDT, a widely used perceptual learning paradigm, participants report the orientation of a target embedded in a field of lines and demonstrate robust over-night improvement. However, changing the orientation of the background lines midway through TDT training interferes with overnight improvements in overall performance on TDT. Interestingly, prior research has suggested that this effect will not occur if a one-hour break is allowed in between the changes. These results have suggested that after training is over, it may take some time for learning to become stabilized and resilient against interference. Here, we tested whether frequent gamers have faster stabilization of perceptual learning compared to non-gamers and examined the effect of daily video game playing on interference of training of TDT with one background orientation on perceptual learning of TDT with a different background orientation. As a result, we found that non-gamers showed overnight performance improvement only on one background orientation, replicating previous results with the interference in TDT. In contrast, frequent gamers demonstrated overnight improvements in performance with both background orientations, suggesting that they are better able to overcome interference in perceptual learning. This resistance to interference suggests that video game playing not only enhances the amplitude and speed of perceptual learning but also leads to faster and/or more robust stabilization of perceptual learning.
Beltran, Alicia; O'Connor, Teresia M; Hughes, Sheryl O; Thompson, Debbe; Baranowski, Janice; Nicklas, Theresa A; Baranowski, Tom
Children can influence the foods available at home, but some ways of approaching a parent may be better than others; and the best way may vary by type of parent. This study explored how parents with different parenting styles would best receive their 10 to 14 years old child asking for fruits and vegetables (FV). An online parenting style questionnaire was completed and follow-up qualitative telephone interviews assessed home food rules, child influence on home food availability, parents' preferences for being asked for food, and common barriers and reactions to their child's FV requests. Parents ( n = 73) with a 10 to 14 years old child were grouped into authoritative, authoritarian, permissive, or uninvolved parenting style categories based on responses to questionnaires, and interviewed. Almost no differences in responses were detected by parenting style or ethnicity. Parents reported their children had a voice in what foods were purchased and available at home and were receptive to their child's asking for FV. The most important child asking characteristic was politeness, especially among authoritarian parents. Other important factors were asking in person, helping in the grocery store, writing requests on the grocery shopping list, and showing information they saw in the media. The barrier raising the most concern was FV cost, but FV quality and safety outside the home environment were also considerations.
Gozzi, Gino; Ganzetti, Alessandra; Martinoli, Carlo; Bacigalupo, Lorenzo; Bodini, Maria; Fiorentino, Carla; Marini, Ugo Paolo; Santini, Dolores
Purpose: To present the mammographic cases most commonly misinterpreted by the participants in the mammography self-test proposed by the Italian Society of Medical Radiology (SIRM) National Congress in Rimini, Italy, 2002, by analysing the findings responsible for errors, suggesting reasons for the errors, and assessing possible inadequacies in the format of the test. Materials and methods: The self-test was performed on the mammograms of 160 cases (32 positive and 128 negative for cancer as confirmed by histology). The mammograms had been taken in the four standard projections and placed on four multi-panel diaphanoscopes, each displaying a set of 40 cases comprising benign and malignant cases in equal proportions. The participants were given pre-printed forms on which to note down their diagnostic judgement. We evaluated a total of 134 fully-completed forms. Among these, we identified the 23 cases most frequently misread by over 15 participants in percentages varying between 40-90%. Of these cases, 10 were malignancies and 13 were negative mammograms. On review, we also assessed the diagnostic contribution of complementary investigations (not available the participants). The 134 fully-completed forms (all of the 40 cases) yielded a total of 5360 responses, 1180 of which (22.01%) were incorrect. Of these 823 out of the 4288 cases expected to be negative (19.2%) were false positive, and 357 out of the 1072 cases expected to be positive (33.3%) were false negative. As regards the 23 most frequently misread cases, these were 10/32 (31.25%) mammograms positive for malignancy and 13/128 (10.15%) negative mammograms or mammograms showing benign disease. The 10 malignancies included 7 infiltrating ductal carcinomas, 1 infiltrating cribriform carcinoma, 1 infiltrating tubular carcinoma, and 1 carcinoma in situ. The 13 cases of benign disease - as established by histology or long-term follow-up - mistaken for malignancies by the test participants were fibrocystic breast
Public information meeting on Monday 28 September 2009 at 10.00 a.m. With effect from 1 August 2009, new provisions regarding staff employment contract policy have entered into force. These provisions are set out in: The Staff Rules and Regulations and Administrative Circular No. 2 (Rev. 4). Further details are available in: Frequently Asked Questions. The new provisions are outlined below: Limited-duration contracts From 1 August 2009, limited-duration contracts will be awarded for a maximum period of five years (instead of four years previously) and no extensions beyond five years will be granted. Contracts for periods shorter than five years can be exceptionally awarded, e.g. for a project whose mission or financial resources are time-limited. Indefinite contracts : award procedure A number of changes have been introduced regarding the procedure for the award of indefinite contracts. From now on, posts leading to the award of an indefinite contract will be opened at le...
Martinenaite, Evelina; Mortensen, Rasmus Erik Johansson; Hansen, Morten
was examined in PBMCs from cancer patients and healthy individuals. IFNγ ELISPOT revealed frequent immune responses against multiple arginase-1-derived peptides. We further identified a hot-spot region within the arginase-1 protein sequence containing multiple epitopes recognized by T cells. Next, we examined......, and further demonstrated the specificity and reactivity of these T cells. Overall, we showed that arginase-1-specific T cells were capable of recognizing arginase-1-expressing cells. The activation of arginase-1-specific T cells by vaccination is an attractive approach to target arginase-1-expressing...... macrophages (TAMs), and its expression is associated with poor prognosis. In the present study, we divided the arginase-1 protein sequence into overlapping 20-amino-acid-long peptides, generating a library of 31 peptides covering the whole arginase-1 sequence. Reactivity towards this peptide library...
Full Text Available Tanweer Karim, Margaret Topno, Vinod Sharma, Raymond Picardo, Ankur HastirSurgery, MGM Medical College, Kamothe, Navi Mumbai, IndiaAbstract: Bladder injuries are very common in patients who have had road traffic accidents. The method of diagnosis and management of such injuries is well established and accepted. However, trauma to the bladder can be associated with other life-threatening injuries which are frequently missed, and often diagnosed during laparotomy for other reasons. The aim of this study was to diagnose bladder injury in polytrauma patients as early as possible, taking into consideration the fact that these patients are hemodynamically unstable and require rapid evaluation and management. In order to achieve our objective, we used bedside sonography with retrograde instillation of normal saline to diagnose bladder injury in addition to use of the conventional retrograde cystogram.Keywords: bladder injury, bladder rupture, retrograde cystogram
López, Laura Beatriz; Ortega Soler, Carlos Rafael; de Portela, María Luz Pita Martín
Pica is the compulsive intake of non-nutritive substances such as earth, clay, chalk, soap and ice. The most common forms of pica are geophagia or the intake of earth and pagophagia or the intake of ice. The description of this peculiar phenomenon dates back to the Greco-Roman civilization. Its prevalence during pregnancy is generally underestimated. Published data reveal a prevalence of between 8% and 65%. Investigations from Latin America indicate a prevalence of 23% to 44%. It is not clear yet which are the causes that predispose to pica, but they are frequently associated with anemia or iron deficiency during pregnancy. Its diagnosis, which only consists in questioning pregnant women, is generally omitted during prenatal care, probably because health professionals have no knowledge about this disorder. The identification of pica in pregnant women could contribute to the detection of a risk group where it is necessary to implement strategies as regards both the evaluation and the nutritional education.
Shockey, Taylor M; Luckhaupt, Sara E; Groenewold, Matthew R; Lu, Ming-Lun
Repeated exposure to occupational ergonomic hazards, such as frequent exertion (repetitive bending or twisting) and frequent standing, can lead to injuries, most commonly musculoskeletal disorders (1). Work-related musculoskeletal disorders have been estimated to cost the United States approximately $2.6 billion in annual direct and indirect costs (2). A recent literature review provided evidence that prolonged standing at work also leads to adverse health outcomes, such as back pain, physical fatigue, and muscle pain (3). To determine which industry and occupation groups currently have the highest prevalence rates of frequent exertion at work and frequent standing at work, CDC analyzed data from the 2015 National Health Interview Survey (NHIS) Occupational Health Supplement (OHS) regarding currently employed adults in the United States. By industry, the highest prevalence of both frequent exertion and frequent standing at work was among those in the agriculture, forestry, fishing, and hunting industry group (70.9%); by occupation, the highest prevalence was among those in the construction and extraction occupation group (76.9%). Large differences among industry and occupation groups were found with regard to these ergonomic hazards, suggesting a need for targeted interventions designed to reduce workplace exposure.
"President General Pervez Musharraf friday asked to give Haams a chance for peace and underscored that the worls which is already in turmoil cannot afford another confrontationist course, says a report received here from Geneva in Switzerlan" (1/2 page)
... your doctor; What to ask your doctor before weight-loss surgery ... What are the reasons someone should have weight-loss surgery? Why is weight-loss surgery not a good choice for everyone who is overweight or obese? What is diabetes ? High blood pressure ? ...
The Importance of Asking Questions - in Different Ways! Uday Maitra. Classroom Volume 20 Issue 1 January 2015 pp 73-75. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/020/01/0073-0075. Keywords. Questions; answers; creativity; classroom teaching. Author Affiliations.
Breivik, Patricia Senn
College administrators are offered a series of questions to ask in evaluating the appropriateness of information technology for their campuses. Issues addressed include defining institutional goals and the role of information technology in them, determining the most effective organization of information resources and technology, and allocation of…
Hinsley, Amy; Sutherland, William J; Johnston, Alison
Gender inequity in science and academia, especially in senior positions, is a recognised problem. The reasons are poorly understood, but include the persistence of historical gender ratios, discrimination and other factors, including gender-based behavioural differences. We studied participation in a professional context by observing question-asking behaviour at a large international conference with a clear equality code of conduct that prohibited any form of discrimination. Accounting for audience gender ratio, male attendees asked 1.8 questions for each question asked by a female attendee. Amongst only younger researchers, male attendees also asked 1.8 questions per female question, suggesting the pattern cannot be attributed to the temporary problem of demographic inertia. We link our findings to the 'chilly' climate for women in STEM, including wider experiences of discrimination likely encountered by women throughout their education and careers. We call for a broader and coordinated approach to understanding and addressing the barriers to women and other under-represented groups. We encourage the scientific community to recognise the context in which these gender differences occur, and evaluate and develop methods to support full participation from all attendees.
Full Text Available Gender inequity in science and academia, especially in senior positions, is a recognised problem. The reasons are poorly understood, but include the persistence of historical gender ratios, discrimination and other factors, including gender-based behavioural differences. We studied participation in a professional context by observing question-asking behaviour at a large international conference with a clear equality code of conduct that prohibited any form of discrimination. Accounting for audience gender ratio, male attendees asked 1.8 questions for each question asked by a female attendee. Amongst only younger researchers, male attendees also asked 1.8 questions per female question, suggesting the pattern cannot be attributed to the temporary problem of demographic inertia. We link our findings to the 'chilly' climate for women in STEM, including wider experiences of discrimination likely encountered by women throughout their education and careers. We call for a broader and coordinated approach to understanding and addressing the barriers to women and other under-represented groups. We encourage the scientific community to recognise the context in which these gender differences occur, and evaluate and develop methods to support full participation from all attendees.
Mathias, Charles W.; Furr, Michael; Sheftall, Arielle H.; Hill-Kapturczak, Nathalie; Crum, Paige; Dougherty, Donald M.
Both researchers and oversight committees share concerns about patient safety in the study-related assessment of suicidality. However, concern about assessing suicidal thoughts can be a barrier to the development of empirical evidence that informs research on how to safely conduct these assessments. A question has been raised if asking about…
... replace all or part of your hip or knee joint with an artificial device (a prosthesis). Below are some questions you may want to ask your health care provider to help you prepare for your hip or knee replacement. Questions Is joint replacement the best treatment ...
Velting, Drew M.; Rathus, Jill H.; Asnis, Gregory M.
Determining suicide risk is a complex matter. A typology of adolescents' most common explanations for discrepant reporting of suicidal behavior is presented. Answers to interview questions were compared to a self-report measure, and adolescent in-patients (N=48) were asked to clarify discrepancies. Seven mutually exclusive and exhaustive…
Children can influence the foods available at home, but some ways of approaching a parent may be better than others; and the best way may vary by type of parent. This study explored how parents with different parenting styles would best receive their 10 to 14 year old child asking for fruit and vege...
This article describes an exercise designed to introduce the topic of Islam and Muslims in a Sociology of Globalization course. The activity asks students to complete a sentence regarding Muslim women. Rather than provide any definitive answers regarding Islam or Muslims, the purpose of the exercise is for students to see the reductive nature of…
... may not absorb all the calories from the food you eat. Below are some questions you may want to ask your health care provider about what will happen after you have the surgery . Questions How much weight will I lose? How fast will I lose it? Will I continue to ...
Document provides clarification and guidance on issues commonly raised regarding the scope of 42 U.S.C. § 8287 et seq. It is a supplement to the Federal Energy Management Program's extensive collection of materials that are available to assist federal agencies execute successful energy savings performance contract (ESPC) projects.
Fuchs, Ota; Kostecka, Arnost; Provaznikova, Dana; Krasna, Blazena; Brezinova, Jana; Filkukova, Jitka; Kotlin, Roman; Kouba, Michal; Kobylka, Petr; Neuwirtova, Radana; Jonasova, Anna; Caniga, Miroslav; Schwarz, Jiri; Markova, Jana; Maaloufova, Jacqueline; Sponerova, Dana; Novakova, Ludmila; Cermak, Jaroslav
C/EBPalpha (CCAAT/enhancer binding protein alpha) belongs to the family of leucine zipper transcription factors and is necessary for transcriptional control of granulocyte, adipocyte and hepatocyte differentiation, glucose metabolism and lung development. C/EBPalpha is encoded by an intronless gene. CEBPA mutations cause a myeloid differentiation block and were detected in acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), multiple myeloma and non-Hodgkin's lymphoma (NHL) patients. In this study we identified in 41 individuals from 824 screened individuals (290 AML patients, 382 MDS patients, 56 NHL patients and 96 healthy individuals) a single class of 23 deletions in CEBPA gene which involved a direct repeat of at least 2 bp. These mutations are characterised by the loss of one of two same repeats at the ends of deleted sequence. Three most frequent repeats included in these deletions in CEBPA gene are CGCGAG (493-498_865-870), GCCAAGCAGC (508-517_907-916) and GG (486-487_885-886), all according to GenBank accession no. NM_004364.2. A mechanism for deletion formation between two repetitive sequences can be recombination events in the repair process. Double-stranded cut in DNA can initiate these recombination events of adjacent DNA sequences.
Full Text Available It is possible to conduct an analysis of the incidence of viral diseases in calves if these diseases are divided into two basic groups. One group comprises diseases of respiratory organs which are manifested by symptoms of a respiratory syndrome, and the second group comprises diseases of digestive tract organs in the form of a gastrointestinal syndrome. It is considered that viruses have the dominant role in the complex etiology of the respiratory syndrome, primarily the IBR virus or the Bovine Herpes Virus-1 (BHV-1, followed by the parainfluenza 3 virus (RSV, the Bovine Viral Diahrrea Virus (BVDV, the bovine Respiratory Syncytial Virus (RSV, but also other viruses, such as adenoviruses, rhinoviruses, coronaviruses, can also influence the appearance of the respiratory syndrome. The respiratory syndrome is rarely caused by a single viral agent, but most frequently by mixed viruses, but also by bacterial infections. Mixed viral infections often have a lethal outcome. Investigations of the etiology of the gastrointestinal syndrome so far indicate that, in addition to bacteria, viruses can also be a significant etiological factor. Rotaviruses, coronaviruses, adenoviruses parvoviruses, herpesviruses (the IBR virus, pestiviruses (BVDV, can be the causes of a gastrointestinal syndrome. It is believed that viruses can be the cause in about 10% cases in the ethiopathogenesis of this syndrome. The paper describes the etiopathogenesis of calf diseases of viral etiology which are most often found in the local conditions of industrial breeding of calves.
biological or genetic factors, thereby disputing the idea that homosexuality is an aberrant behavior [Ref. 60]; the presence of " homophobia " in the...teachings. That’s a hard question because I’m not up on what other religions are saying.. .I’m a Roman Catholic.. .they say love your brother.. .but we...don’t like homosexuals. I guess we’re more tolerant than your southern baptists or southern christian religions . That was a good question I think. Q
Shauna M. Haley
Full Text Available Nature starts the news week by chronicling epidemiological researchers’ wrath over how Britain’s General Medical Council (GMC has implemented the nation’s 1998 Data Protection Act. Science fires up its news with coverage of the torching of two plant labs in the northwestern U.S. by ecoterrorists.
open GLs to serve.27 In fact, experts note that the United Kingdom lifted their GL ban in 2000 and Russia did the same in 2003.28 In 2000, the RAND...television series such as The Real World: San Francisco in 1993; The Real World: Miami; Richard Hatch on Survivor in 2000; and Queer Eye for the
The law affords potential recruits the opportunity to reconcile differences between 4 military standards and their personal sexual preferences before...sexual orientation, but it also allows heterosexual military personnel to demean unknown gays serving in the ranks – a violation of the core value of...this expectation as unfair and narrow-minded since heterosexuals are not generally required to put their sex life on pause. Consequently, a failure to
Monroe, Todd; Kenaga, Heidi
The purpose of this manuscript is to illustrate the challenges faced by nurses who abuse substances and to promote international dialogue about what practitioners, administrators, health care providers and students can do when they suspect someone in the profession is abusing substances, or they may themselves be suffering from addiction. Addiction among nurses has been recognised by professionals in the field for over 100 years, and current estimates place rates of substance misuse, abuse and addiction rates as high as 20% among practicing nurses. Unfortunately, fear of punishment and discipline may keep nurses or students from asking for help for themselves or from reporting a colleague or friend who is in need of help. Discursive paper. This paper synthesises the results of three previous papers conducted on substance abuse policies in the nursing profession. In the first paper, the authors reviewed the history of addiction in nursing and compared disciplinary and alternative-to-discipline policies. The second focused on the development of an alternative-to-dismissal policy for substance abuse in a school of nursing and using telephone and email interviews, and the final paper reported findings of what types of policies seem to be working to retain and rehabilitate nurses who suffer from addiction in the USA. Lastly, this paper introduces international policy for nurses with addictions. Poor or ineffective policies that mandate punitive action endanger the public by making it difficult for impaired students or professionals to ask for help. Providing early intervention and assistance is essential in helping colleagues and students recover from an addictive disorder and providing a non-punitive atmosphere of support may well be a life-saving first step for nurses and those in their care. Many territories and countries throughout the world now offer confidential, non-punitive, assistance for nurses suffering from addictions. Recognition of a colleague's need of
Strike, Carol; Rudzinski, Katherine; Patterson, Jessica; Millson, Margaret
Food insecurity and nutrition are two topics that are under-researched among injection drug users (IDUs). Our study examined the extent and correlates of food insecurity among a sample of IDUs and explored whether there is an association between food insecurity and injection-related HIV risk. A cross-sectional survey was conducted using interviewer-administered questionnaires. Data were collected at a needle exchange program in London, Ontario, Canada between September 2006 and January 2007. Participants included 144 English-speaking IDUs who had injected drugs in the past 30 days. Participants were asked about their socio-demographic characteristics, HIV risk behaviours, food insecurity, and health/social service use. In the past 6 months, 54.5% of participants reported that on a daily/weekly basis they did not have enough to eat because of a lack of money, while 22.1% reported this type of food insecurity on a monthly basis. Moreover, 60.4% and 24.3% reported that they did not eat the quality or quantity of food they wanted on a daily/weekly or a monthly basis, respectively. Participants reported re-using someone else's injection equipment: 21% re-used a needle, 19% re-used water, and 37.3% re-used a cooker. The odds of sharing injection equipment were increased for food insecure individuals. Findings show that IDUs have frequent and variable experiences of food insecurity and these experiences are strongly correlated with sharing of injection-related equipment. Such behaviours may increase the likelihood of HIV and HCV transmission in this population. Addressing food-related needs among IDUs is urgently needed.
Mathias, Charles W.; Furr, R. Michael; Sheftall, Arielle H.; Hill-Kapturczak, Nathalie; Crum, Paige; Dougherty, Donald M.
Both researchers and oversight committees share concerns about patient safety in the study-related assessment of suicidality. However, concern about assessing suicidal thoughts can be a barrier to the development of empirical evidence that informs research on how to safely conduct these assessments. A question has been raised if asking about suicidal thoughts can result in iatrogenic increases of such thoughts, especially among at-risk samples. The current study repeatedly tested suicidal ideation at 6-month intervals for up to 2-years. Suicidal ideation was measured with the Suicidal Ideation Questionnaire Junior, and administered to adolescents who had previously received inpatient psychiatric care. Change in suicidal ideation was tested using several analytic techniques, each of which pointed to a significant decline in suicidal ideation in the context of repeated assessment. This and previous study outcomes suggest that asking an at-risk population about suicidal ideation is not associated with subsequent increases in suicidal ideation. PMID:22548324
Beltran, Alicia; O?Connor, Teresia M.; Hughes, Sheryl O.; Thompson, Debbe; Baranowski, Janice; Nicklas, Theresa A.; Baranowski, Tom
Children can influence the foods available at home, but some ways of approaching a parent may be better than others; and the best way may vary by type of parent. This study explored how parents with different parenting styles would best receive their 10 to 14 years old child asking for fruits and vegetables (FV). An online parenting style questionnaire was completed and follow-up qualitative telephone interviews assessed home food rules, child influence on home food availability, parents? pre...
Hinsley, Amy; Sutherland, William J.; Johnston, Alison
Gender inequity in science and academia, especially in senior positions, is a recognised problem. The reasons are poorly understood, but include the persistence of historical gender ratios, discrimination and other factors, including gender-based behavioural differences. We studied participation in a professional context by observing question-asking behaviour at a large international conference with a clear equality code of conduct that prohibited any form of discrimination. Accounting for au...
Obšil, Tomáš; Obšilová, Veronika
Roč. 66, 1 Dec (2017), s. 31-36 ISSN 2212-4926 R&D Projects: GA ČR(CZ) GA16-02739S; GA MŠk(CZ) ED1.1.00/02.0109 Institutional support: RVO:67985823 Keywords : ASK1 kinase * apoptosis * thioredoxin * 14-3-3 protein Subject RIV: CE - Biochemistry OBOR OECD: Biochemistry and molecular biology
or no answer. To support the use of prompts that require more behavior on the part of the student, Skinner quotes Comenius : "The more the teacher...neither a Socratic method of asking leading questions nor can it be reduced to Comenius ’ contention that students should not be challenged beyond levels...development of higher psychological processes (M. Cole, V. John -Steiner, S. Scribner, & E. Souberman, Eds.). Cambridge, MA: Harvard University Press. Weaver
Kaysen, George A.; Greene, Tom; Larive, Brett; Mehta, Ravindra, L.; Lindsay, Robert; Depner, Tom A.; Hall, Yoshio N.; Daugirdas, John T.; Chertow, Glenn M.
We investigated the effects of frequency of hemodialysis on nutritional status by analyzing the data in the Frequent Hemodialysis Network Trial. We compared changes in albumin, body weight and composition among 245 patients randomized to 6- or 3-times per week in-center hemodialysis (Daily Trial) and 87 patients randomized to 6-times per week nocturnal or 3-times per week conventional hemodialysis, performed largely at home (Nocturnal Trial). In the Daily Trial, there were no significant diff...
French, Judith C; Colbert, Colleen Y; Pien, Lily C; Dannefer, Elaine F; Taylor, Christine A
The Accreditation Council for Graduate Medical Education's Milestones Project focuses trainee education on the formation of valued behaviors and skills believed to be necessary for trainees to become independent practitioners. The development and refinement of behaviors and skills outlined within the milestones will require learners to monitor, reflect, and assess their own performance over time. External feedback provides an opportunity for learners to recalibrate their self-assessments, thereby enabling them to develop better self-monitoring and self-assessment skills. Yet, feedback to trainees is frequently generic, such as "great job," "nice work," or "you need to read more." In this article, we describe a feedback model that faculty can use to provide specific feedback, while increasing accountability for learners. We offer practical examples of its use in a variety of settings in the milestone era. The Ask-Tell-Ask (ATA) patient communication skills strategy, which was adapted for use as a trainee feedback model 10 years ago at our institution, is a learner-centered approach for reinforcing and modifying behaviors. The model is efficient, promotes learner accountability, and helps trainees develop reflection and self-assessment skills. A feedback agreement further enhances ATA by establishing a shared understanding of goals for the educational encounter. The ATA feedback model, combined with a feedback agreement, encourages learners to self-identify strengths and areas for improvement, before receiving feedback. Personal monitoring, reflection, self-assessment, and increased accountability make ATA an ideal learner-centered feedback model for the milestones era, which focuses on performance improvement over time. We believe the introduction of the ATA feedback model in surgical training programs is a step in the right direction towards meaningful programmatic culture change. Copyright © 2015 Association of Program Directors in Surgery. Published by Elsevier
Kaysen, George A.; Greene, Tom; Larive, Brett; Mehta, Ravindra, L.; Lindsay, Robert; Depner, Tom A.; Hall, Yoshio N.; Daugirdas, John T.; Chertow, Glenn M.
We investigated the effects of frequency of hemodialysis on nutritional status by analyzing the data in the Frequent Hemodialysis Network Trial. We compared changes in albumin, body weight and composition among 245 patients randomized to 6- or 3-times per week in-center hemodialysis (Daily Trial) and 87 patients randomized to 6-times per week nocturnal or 3-times per week conventional hemodialysis, performed largely at home (Nocturnal Trial). In the Daily Trial, there were no significant differences between groups in changes in serum albumin or the equilibrated protein catabolic rate by 12 months. There was a significant relative decrease in pre-dialysis body weight of 1.5 ± 0.2 kg in the 6 times per week group at one month, but this significantly rebounded by 1.3 ± 0.5 kg over the remaining 11 months. Extracellular water decreased in the 6 times per week compared to the 3 per week hemodialysis group. There were no significant between-group differences in phase angle, intracellular water or body cell mass. In the Nocturnal Trial, there were no significant between-group differences in any study parameter. Any gain in “dry” body weight corresponded to increased adiposity rather than muscle mass but was not statistically significant. Thus, frequent in-center hemodialysis reduced extracellular water but did not increase serum albumin or body cell mass while frequent nocturnal hemodialysis yielded no net effect on parameters of nutritional status or body composition. PMID:22456602
Full Text Available Old fi ndings on children’s comprehension of ask and tell were subject todifferent interpretations refl ecting progress in the fi eld of language acquisition.We want to show that acquiring a particular skill does not necessarily includecompetence of its intentional control and use. Development of linguistic skillstakes place at different levels starting from early spontaneous, implicit abilitiesto the level of meta-pragmatic refl exive knowledge that enables deliberatemonitoring, planning, and practice. The present study was aimed at exploringtwo extreme points in development: early epi-pragmatic and late refl exive metapragmaticcompetence. The fi rst part aims at fi nding the earliest instancesof children spontaneous ability to pass ask-instructions, and the evidence isprovided for the ages as early as 22 to 40 months (much earlier than recorded inthe previous studies. The second part is experimental and focuses on children’sability to respond to ask- and tell-instructions in the context of a cancelledconversational rule (Gricean Maxim of Quantity which requires deliberatemonitoring and use. The results show that this meta-pragmatic refl exive abilitybecomes stable only at the age of 6 years.
Ashcraft, Phillip Lynn [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Fogle, Blythe G. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Cummings, Susan M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Lopez, Leon [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
This was prepared for the business process improvement presentation to the Department of Energy. Los Alamos National Laboratory provides a single point of contact, the AskIT Service Desk, to address issues that impact customer productivity. At the most basic level, what customers want is for their calls to be received, to get a response from a knowledgeable analyst, and to have their issues resolved and their requests fulfilled. Providing a centralized, single point of contact service desk makes initiating technical or business support simple for the customer and improves the odds of immediately resolving the issue or correctly escalating the request to the next support level when necessary. Fulfilling customer requests through automated workflow also improves customer productivity and reduces costs. Finally, customers should be provided the option to solve their own problems through easy access to self-help resources such as frequently asked questions (FAQs) and how-to guides. To accomplish this, everyone who provides and supports services must understand how these processes and functions work together. Service providers and those who support services must “speak the same language” and share common objectives. The Associate Directorate for Business Innovation (ADBI) began the journey to improve services by selecting a known service delivery framework (Information Technology Infrastructure Library, or ITIL). From this framework, components that contribute significant business value were selected.
Elizabeth Wulan Wahyuningtyas; Fransiska Selvy Wulandari
Through frequent test, students have higher self-motivation to understand every material in order to make them prepared in attending frequent test. This paper aims to see the teachers’ and students’ perceptions on frequent test. In addition, as the further finding, the writers will focus on the benefits of frequent test. The paper is an observation paper that focused on students ‘and teachers’ perception through frequent test, and its benefits. The finding shows that both of the teachers and ...
Payroll expenses may account for over half of all of a hospital's expenses. Manual time card processing requires an abundance of staff time and can often result in costly errors. To alleviate this problem, many healthcare facilities are implementing computerized labor information systems. To minimize the risk of selecting the wrong system, hospital administrators should ask the following questions before committing to any computerized labor information system: Is the software designed for hospital use and easily adaptable to each hospital's unique policies? How flexible is the software's reporting system? Does it include automatic scheduling that creates generic schedules? Does the system have the capability of securing time and attendance records and documenting the audit trail? Does the system include an accurate and reliable badge reader? What type of hardware is best for the particular hospital--microcomputer, minicomputer, or mainframe? Finally, to guarantee successful software installation, the vendor should have extensive experience and documentation in the system's implementation.
This study assesses the role of LGBT advocates in repealing the military's Don't Ask, Don't Tell policy in the U.S. Congress. It draws on the author's direct involvement with that effort as well as personal interviews and media evidence to consider the contributions of the Obama Administration, members of Congress, the media, and individuals and pressure groups in the repeal process. It argues that repeal succeeded not because of the effective implementation of a White House plan but because the pressure of LGBT advocates ultimately shattered several key obstacles including inadequate messaging and dysfunction and inertia among both politicians and interest groups in Washington. The article offers insight into the role of public pressure in forwarding social change.
Gillian S. Gould
Full Text Available Clinicians often ask pregnant women about tobacco smoking, but their practices of asking about other smoking and nicotine exposures are unknown. This study analysed how often clinicians ask pregnant women about their use of e-cigarettes, cannabis, chewing tobacco, and second-hand smoke (SHS exposure. Two cross-sectional surveys were undertaken. A random sample of 500 General Practitioner (GP members were invited from the National Faculty of Aboriginal and Torres Strait Islander Health (NFATSIH to complete an on-line survey, and 5571 GP and Obstetrician (OBS members of the Royal Australian and New Zealand College of Obstetricians and Gynaecologists (RANZCOG were sent a paper survey by mail. Questions on frequency of asking about the exposures used Likert Scales, later dichotomized to “often-always” and “never-sometimes”. Logistic regressions estimated associations between clinician type and asking about cannabis, e-cigarettes, chewing tobacco, and SHS. An adjusted model reduced potential confounders of location, guidelines, gender and population. n = 378 GPs and OBS participated (6.2% response. In total, 13–14% asked “often-always” about e-cigarettes; 58% cannabis; 38% cannabis with tobacco; 27% SHS, and 10% chewing tobacco—compared to 95% of the sample asking about cigarette smoking. After adjustment, the odds of RANZCOG GPs (OR 0.34 and OBS (OR 0.63 asking about cannabis were lower compared to NFATSIH GPs. Clinician type was non-significant for asking about e-cigarettes, chewing tobacco and SHS. Surveyed Australian GPs and obstetricians asked less frequently about e-cigarettes, chewing, SHS exposure, and cannabis, potentially missing important exposures for mother and child.
Quesada Rodriguez, Marco V.
A set of instructions and / or recommendations are afforded, developed in a systematic way, whose purpose is to help treating doctors to make decisions about the mode of study appropriate for a specialized clinical circumstance. The instructions are aimed at radiologists, in order to facilitate the selection and realization of special studies in the pediatric patient images, so that in this way, guide of the best and most efficient way to the resolution of the cases before diagnostic doubts that seek to clarify the treating clinician. The studies most frequently requested are exposed, as well as those with their prompt realization will lead to a quick and timely medical care and / or surgical of a specific problem [es
James, Ian Andrew; Morse, Rachel; Howarth, Alan
Questions underpin all aspects of therapeutic assessment and intervention and are a vital component of the clinical process. Over recent years frameworks have started to be applied to obtain a greater understanding of questioning formats and processes. This paper examines the use of questions in cognitive therapy (CT). An overview of the main types of questions identified in the literature is presented. In addition, we examine a range of client and therapist characteristics that may impact on the questioning process. Asking questions in therapy is a complex, yet under-taught, skill. This paper provides a set of frameworks to assist in identifying helpful and unhelpful questioning skills. Thus the article has implications for further training and research.
Ipema, Karin; Franssen, Casper; van der Schans, Cees; Smit, Lianne; Noordman, Sabine; Haisma, Hinke
Objective: Dialysis patients frequently report a change of taste that is reversible after renal transplantation, suggesting that uremic toxins may negatively influence taste. Currently, frequent nocturnal home hemodialysis (NHHD) is the most effective method of hemodialysis, and is associated with
Luis dos Ramos Machado
Full Text Available Cerebrospinal fluid (CSF analysis very frequently makes the difference to the diagnosis, not only in relation to infections but also in other diseases of the nervous system such as inflammatory, demyelinating, neoplastic and degenerative diseases. The authors review some practical and important features of CSF analysis in infectious diseases of the nervous system, with regard to acute bacterial meningitis, herpetic meningoencephalitis, neurotuberculosis, neurocryptococcosis, neurocysticercosis and neurosyphilis.
This document is a guide to accessing the Internet and the services available on Internet. The document contains a short explanation of the Internet by E. Kroll and E. Hoffman, brief descriptions of the primary access tools, a glossary, answers to frequently asked questions about the Internet, J. Martin`s `Search for Internet Treasure` and other helpful information. The data access tools discussed in this document include Gopher, World Wide Web, WAIS, ASTRA, ARCHIE, WHOIS, NETSERV, and TRICKLE. The file transfer tool discussed is BITFTP. The two communication services discussed are NETNEWS and LISTSERV.
Health professionals often have to write articles for publication in academic journals. Many of them find this difficult and suffer from one or more variations of writer's block. A good way of avoiding these setbacks is to prepare thoroughly for the writing project, and this article proposes eight different questions writers can ask before they start. The first is whether they are in a good position to complete the task, and if not whether they should try to negotiate their way out of the project. If they commit to going ahead, writers should work out where they will find the necessary time, and set deadlines for ensuring that they do. They should also decide on their co-authors, because getting them involved early should make the rewriting more straightforward as well as reducing the danger of ghost authors emerging once the work has been done. Writers should put their research away and reflect on the most appropriate message - a simple sentence that sums up the main implication of the paper. Armed with this message, they can identify a suitable journal for publication - and thereafter can use articles in this journal to guide them on matters of substance and style. If the article is published in that target journal authors can consider that they have written a successful paper.
Ashcraft, Phillip Lynn [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Cummings, Susan M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Fogle, Blythe G. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Valdez, Christopher D. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
The value model discussed herein provides an accurate and simple calculation of the funding required to adequately staff the AskIT Service Desk (SD). The model is incremental – only technical labor cost is considered. All other costs, such as management, equipment, buildings, HVAC, and training are considered common elements of providing any labor related IT Service. Depending on the amount of productivity loss and the number of hours the defect was unresolved, the value of resolving work from the SD is unquestionably an economic winner; the average cost of $16 per SD resolution can commonly translate to cost avoidance exceeding well over $100. Attempting to extract too much from the SD will likely create a significant downside. The analysis used to develop the value model indicates that the utilization of the SD is very high (approximately 90%). As a benchmark, consider a comment from a manager at Vitalyst (a commercial IT service desk) that their utilization target is approximately 60%. While high SD utilization is impressive, over the long term it is likely to cause unwanted consequences to staff such as higher turnover, illness, or burnout. A better solution is to staff the SD so that analysts have time to improve skills through training, develop knowledge, improve processes, collaborate with peers, and improve customer relationship skills.
Ramirez, Maria Heliana; Rogers, Stephen Joseph; Johnson, Harriet Lee; Banks, Jon; Seay, Wanda Penny; Tinsley, Billy Lee; Grant, Andrew Warren
Following repeal of the Don't Ask Don't Tell Policy, nearly one million lesbian, gay, and bisexual veterans and service members may increasingly seek access to Veterans Affairs services (G. Gates, 2004; G. J. Gates, 2010). Limited data exist regarding lesbian, gay, bisexual, transgender (LGBT) military personnel posing a unique challenge to clinicians and healthcare systems serving veterans with evidence-based and culturally relevant practice. In an effort to fill this information void, participatory program evaluation is used to inform recommendations for LGBT-affirmative health care systems change in a post-DADT world.
Kjærulff, Thora M; Rivera, Francisco; Jiménez-Iglesias, Antonia
AIM: The aim of the study was to examine, for female and male students separately, whether perceived quality of relationships with peers and parents and relations in school predict self-reported frequent drunkenness among Spanish adolescents. METHODS: The Spanish data from the Health Behaviour...... odds of frequent drunkenness compared with those with high level of satisfaction with friendships. CONCLUSION: We found different associations between perceived quality of social relations and frequent drunkenness among male and female students. Results showed that social relations seemed to better...... predictors of frequent drunkenness among female than male students and that other factors than social relations may contribute to explain excessive alcohol use among Spanish adolescents....
Children are natural scientists. They ask questions, they observe, they try things to see what happens. Often school-based science does little to nurture the young scientist and, in fact, may do just the opposite with thick textbooks, fact heavy lessons, and too many equations. The exploration of common toys produces deep learning by emphasizing concepts and connections before formal definitions and mathematics. It also connects the classroom to the familiar world outside of school and gets students writing and talking about physics ideas. At the university level, investigating what toys do and how they do it can be a challenging application of undergraduate physics from the introductory course up through senior mechanics. Toys provide an ideal system for the kind of open-ended inquiry that introduces students to what scientists really do. They can pose their own questions, explore the behavior of the system sufficiently to create a hypothesis, use their theoretical knowledge to make a simplified model of the system and predict an outcome, design an experiment, discover that the real world is messy, think about what they haven't taken into account with their simple model and try to improve it. I have spent close to 30 years thinking about how to use toys to enhance physics education from 4th grade through college. In the process I have collected hundreds of toys the majority of which relate to mechanics, but also to sound, light, electricity and magnetism. I will discuss the pedagogical reasons for using toys in physics education and the many different ways to use them from demonstrations to laboratory experiments to discussion starters as well as how it is possible to use the same toy with many different age levels by approaching the analysis differently. I will share a number of my favorite toys, but focus particularly on those related to energy concepts.
Full Text Available Education researchers who study the effect of family social background on student achievement often use students’ survey reports of parental education to investigate these effects. However, past research has demonstrated that students misreport their parents’ education levels. We expand upon this research in two ways. First we use cognitive theories about the response process to develop and test hypotheses about reporting inconsistencies across these variables. Second we evaluate the impact of student misreporting on estimates of the relationship between parental education levels and student math achievement. Using data from the German administration of PISA 2000 (OECD Programme for International Student Assessment in which both students and parents were asked to report parental variables, we show that reporting inconsistencies are a function of student achievement: students with higher math scores tend to provide reports that are more consistent with their parents' reports. This interesting case of differential measurement error has consequences for comparisons of the effects of parental background on student achievement across different subgroups of the population and across countries (a common use of PISA data and other international studies similar to PISA.
Lankes, R. David
Explores major issues in creating and maintaining Internet services for AskERIC, an educational digital library started by the Educational Resources Information Center (ERIC) system. Highlights include the importance of user input to shape the service, human intermediaries, AskERIC as a virtual library, future directions, and a copy of the AskERIC…
The childhood obesity epidemic has prompted a range of regulatory initiatives that seek to reduce the impact of food marketing on children. Policy recommendations by government and public health organizations have suggested regulating the promotion of high-sugar, -fat, and/or -salt foods to children, while the food industry has created voluntary nutrition guidelines to channel child-targeted marketing toward only "better-for-you" products. This article argues that the overarching focus on the nutrient profile of foods (nutritionism) is wrong-headed: The slippage in terms from "better-for-you" foods to "healthy dietary choices" is problematic and also makes it difficult for children to identify the healthy choice. Nutritionism further works to sidestep important questions pertaining to the ethics of food marketing, not to mention the way that marketing foods as fun and entertainment works to encourage overeating in children.
Goldbach, Jeremy T; Castro, Carl Andrew
Lesbian, gay, and bisexual service members can serve openly in the military with the repeal of the Don't Ask, Don't Tell policy. The fate of transgender service members remains uncertain as the policy preventing them from serving in the military remains under review. The health care needs of these populations remain for the most part unknown, with total acceptance and integration in the military yet to be achieved. In this paper, we review the literature on the health care needs of lesbian, gay, bisexual, and transgender (LGBT) service members, relying heavily on what is known about LGBT civilian and veteran populations. Significant research gaps about the health care needs of LGBT service members are identified, along with recommendations for closing those gaps. In addition, recommendations for improving LGBT acceptance and integration within the military are provided.
Marc L. Martel
Full Text Available Introduction: A subset of frequent users of emergency services are those who use the emergency department (ED for acute alcohol intoxication. This population and their ED encounters have not been previously described. Methods: This was a retrospective, observational, cohort study of patients presenting to the ED for acute alcohol intoxication between 2012 and 2016. We collected all data from the electronic medical record. Frequent users for alcohol intoxication were defined as those with greater than 20 visits for acute intoxication without additional medical chief complaints in the previous 12 months. We used descriptive statistics to evaluate characteristics of frequent users for alcohol intoxication, as well as their ED encounters. Results: We identified 32,121 patient encounters. Of those, 325 patients were defined as frequent users for alcohol intoxication, comprising 11,370 of the encounters during the study period. The median maximum number of encounters per person for alcohol intoxication in a one-year period was 47 encounters (range 20 to 169. Frequent users were older (47 years vs. 39 years, and more commonly male (86% vs. 71%. Frequent users for alcohol intoxication had higher rates of medical and psychiatric comorbidities including liver disease, chronic kidney disease, ischemic vascular disease, dementia, chronic obstructive pulmonary disease, history of traumatic brain injury, schizophrenia, and bipolar disorder. Conclusion: In this study, we identified a group of ED frequent users who use the ED for acute alcohol intoxication. This population had higher rates of medical and psychiatric comorbidities compared to non-frequent users.
Aim of the study: This study was conducted to evaluate the frequency of iron deficiency and relevant factors in frequent and first time female blood donors at Casablanca blood transfusion centre, Morocco. Methods: Between November 2005 and April 2006, twenty-one female first time and twenty-one frequent female blood ...
Vedsted, Peter; Olesen, Frede
of 1423 (73.7%) frequent attenders and 1103 (74.9%) infrequent attenders responded. Male frequent attendance was associated, with statistical significance, with living alone and being without work or on a disability pension. Among women, lack of professional education or being without work tended...
W.H.L.M. Pijls (Wim); R. Potharst (Rob)
textabstractIn this technical report , two new algorithms based upon frequent patterns are proposed. One algorithm is a classification method. The other one is an algorithm for target group selection. In both algorithms, first of all, the collection of frequent patterns in the training set is
Ding, Tienan; Li, Wei; Li, Xiongfei
XML data is widely used in the information exchange field of Internet, and XML document data clustering is the hot research topic. In the XML document clustering process, measure differences between two XML documents is time costly, and impact the efficiency of XML document clustering. This paper proposed an XML documents clustering method based on frequent patterns of XML document dataset, first proposed a coding tree structure for encoding the XML document, and translate frequent pattern mining from XML documents into frequent pattern mining from string. Further, using the cosine similarity calculation method and cohesive hierarchical clustering method for XML document dataset by frequent patterns. Because of frequent patterns are subsets of the original XML document data, so the time consumption of XML document similarity measure is reduced. The experiment runs on synthetic dataset and the real datasets, the experimental result shows that our method is efficient.
Full Text Available Homelessness, HIV, and substance use are interwoven problems. Furthermore, homeless individuals are frequent users of emergency services. The main purpose of this study was to identify risk factors for frequent emergency room (ER visits and to examine the effects of housing status and HIV serostatus on ER utilization. The second purpose was to identify risk factors for frequent ER visits in patients with a history of illicit drug use.A retrospective analysis was performed on 412 patients enrolled in a Boston-based health care for the homeless program (HCH. This study population was selected as a 2:1 HIV seronegative versus HIV seropositive match based on age, sex, and housing status. A subgroup analysis was performed on 287 patients with history of illicit drug use. Chart data were analyzed to compare demographics, health characteristics, and health service utilization. Results were stratified by housing status. Logistic models using generalized estimating equations were used to predict frequent ER visits.In homeless patients, hepatitis C was the only predictor of frequent ER visits (OR 4.49, p<0.01. HIV seropositivity was not predictive of frequent ER visits. In patients with history of illicit drug use, mental health (OR 2.53, 95% CI 1.07-5.95 and hepatitis C (OR 2.85, 95% CI 1.37-5.93 were predictors of frequent ER use. HIV seropositivity did not predict ER use (OR 0.45, 95% CI 0.21 - 0.97.In a HCH population, hepatitis C predicted frequent ER visits in homeless patients. HIV seropositivity did not predict frequent ER visits, likely because HIV seropositive HCH patients are engaged in care. In patients with history of illicit drug use, hepatitis C and mental health disorders predicted frequent ER visits. Supportive housing for patients with mental health disorders and hepatitis C may help prevent unnecessary ER visits in this population.
Thakarar, Kinna; Morgan, Jake R; Gaeta, Jessie M; Hohl, Carole; Drainoni, Mari-Lynn
Homelessness, HIV, and substance use are interwoven problems. Furthermore, homeless individuals are frequent users of emergency services. The main purpose of this study was to identify risk factors for frequent emergency room (ER) visits and to examine the effects of housing status and HIV serostatus on ER utilization. The second purpose was to identify risk factors for frequent ER visits in patients with a history of illicit drug use. A retrospective analysis was performed on 412 patients enrolled in a Boston-based health care for the homeless program (HCH). This study population was selected as a 2:1 HIV seronegative versus HIV seropositive match based on age, sex, and housing status. A subgroup analysis was performed on 287 patients with history of illicit drug use. Chart data were analyzed to compare demographics, health characteristics, and health service utilization. Results were stratified by housing status. Logistic models using generalized estimating equations were used to predict frequent ER visits. In homeless patients, hepatitis C was the only predictor of frequent ER visits (OR 4.49, phomeless patients. HIV seropositivity did not predict frequent ER visits, likely because HIV seropositive HCH patients are engaged in care. In patients with history of illicit drug use, hepatitis C and mental health disorders predicted frequent ER visits. Supportive housing for patients with mental health disorders and hepatitis C may help prevent unnecessary ER visits in this population.
Thakarar, Kinna; Morgan, Jake R.; Gaeta, Jessie M.; Hohl, Carole; Drainoni, Mari-Lynn
Background Homelessness, HIV, and substance use are interwoven problems. Furthermore, homeless individuals are frequent users of emergency services. The main purpose of this study was to identify risk factors for frequent emergency room (ER) visits and to examine the effects of housing status and HIV serostatus on ER utilization. The second purpose was to identify risk factors for frequent ER visits in patients with a history of illicit drug use. Methods A retrospective analysis was performed on 412 patients enrolled in a Boston-based health care for the homeless program (HCH). This study population was selected as a 2:1 HIV seronegative versus HIV seropositive match based on age, sex, and housing status. A subgroup analysis was performed on 287 patients with history of illicit drug use. Chart data were analyzed to compare demographics, health characteristics, and health service utilization. Results were stratified by housing status. Logistic models using generalized estimating equations were used to predict frequent ER visits. Results In homeless patients, hepatitis C was the only predictor of frequent ER visits (OR 4.49, phealth (OR 2.53, 95% CI 1.07–5.95) and hepatitis C (OR 2.85, 95% CI 1.37–5.93) were predictors of frequent ER use. HIV seropositivity did not predict ER use (OR 0.45, 95% CI 0.21 – 0.97). Conclusions In a HCH population, hepatitis C predicted frequent ER visits in homeless patients. HIV seropositivity did not predict frequent ER visits, likely because HIV seropositive HCH patients are engaged in care. In patients with history of illicit drug use, hepatitis C and mental health disorders predicted frequent ER visits. Supportive housing for patients with mental health disorders and hepatitis C may help prevent unnecessary ER visits in this population. PMID:25906394
Laufer, Alexander (Editor); Collins, Michelle (Editor); Post, Todd (Editor)
several times so that they would be able to focus in detail on the many areas of the program that would be scrutinized during the certification inspection. These are just a sampling of some of the articles you'll find in this issue of ASK. We believe this issue offers ample evidence that talented Project Managers know how to use reviews to the great benefit of their projects. A talented Project Manager will typically figure out a way to turn any onerous task into a useful learning exercise. These Project Managers demonstrate that the real value of reviews is that they provide a chance to learn something. No dog and pony shows here.
Pasgaard, Alexander A.; Mæhlisen, Maiken H.; Overgaard, Charlotte
and individual social capital. The aim of this study is to explore this association. METHODS: The analysis is conducted on responders to the North Denmark Region Health Profile 2010 (n = 23,384), individually linked with information from administrative registers. Social capital is operationalized......BACKGROUND: Frequent attendance to primary care constitutes a large use of resources for the health care system. The association between frequent attendance and illness-related factors has been examined in several studies, but little is known about the association between frequent attendance...
Campagna, Andrea; Kutzkow, Konstantin; Pagh, Rasmus
We introduce the Pair Streaming Engine (PairSE) that detects frequent pairs in a data stream of transactions. Our algorithm finds the most frequent pairs with high probability, and gives tight bounds on their frequency. It is particularly space efficient for skewed distribution of pair supports...... items mining in data streams. We show how to efficiently scale these approaches to handle large transactions. We report experimental results showcasing precision and recall of our method. In particular, we find that often our method achieves excellent precision, returning identical upper and lower...... bounds on the supports of the most frequent pairs....
Mazza, I.; van Winden, F.
Endogenous policy models usually neglect that government policies are frequently the result of decisions taken at different tiers by different agents, each enjoying some degree of autonomy. In this paper, policies are the outcome of the choices made by two agents within a hierarchy. A legislator
Andres Velasco; Alejandro Neut
We revisit the question of what determines the credibility of macroeconomic policies here, of promises to repay public debt. Almost all thinking on the issue has focused on governments' strategic decision to default (or erode the value of outstanding debt via inflation/devaluation). But sometimes governments default not because they want to, but because they cannot avoid it: adverse shocks leave them no option. We build a model in which default/devaluation can occur deliberately (for strategi...
Frequent technical questions such Surface Impoundment Requires Corrections, How Do I Assess Toxicity Characteristic Leaching Procedure (TCLP) or Leachability in a Liquid Waste Sample?, Aggregate Hazard Index and Cancer Risk Output Table Correction.
Reilev, Mette; Lykkegaard, Jesper; Halling, Anders
Exacerbation frequency is central in treatment strategies for chronic obstructive pulmonary disease. However, whether chronic obstructive pulmonary disease patients from the general population with frequent exacerbations continue to have frequent exacerbations over an extended period of time...... is currently unknown. In this study, we aimed to investigate the stability of the frequent exacerbator in a population-based setting. To this end, we conducted a nationwide register-based descriptive study with a 10-year follow-up period of chronic obstructive pulmonary disease patients with at least one...... no additional years as frequent exacerbators, while the minority (6%) remained in this category each year. In conclusion, the rate of exacerbations shows considerable variation over time among chronic obstructive pulmonary disease patients in the general population. This might hold implications for chronic...
Full Text Available The incidence of some skin diseases are increasing at adolescent and early adulthood period. The most frequent disease at this period is acne vulgaris whereas fungal diseases, dermatitis, dermatosis which are due to stress and other reasons, oral mucosal lesions and herpetic lesions of perioral region are also frequent. In this research we aim to determine the frequent dermatologic diseases of university students and 147 female, 74 male, a total of 221 students are included. We questioned the dermatologic complaints of students, then examined dermatologically in detail and registered ages, sexes, findings of the dermatological examination and dermatological diagnostic informations. As a result it is found out that the most frequent diseases are acne vulgaris (34.1%, allergic and pruritic dermatosis (16.6%, fungal diseases ( 13.0%, and eritamatous-squamous disease (8.3%. [TAF Prev Med Bull 2005; 4(6.000: 313-320
Full Text Available “The proper business of school is to teach students to think!” has been the most widespread cliché in education over the last two decades (Squire, 1983; Paris, Lipson & Wixson, 1983; Spires et alli, 1993; Littlewood, 1996; Collins, 1998; Yang, 1998; Shneiderman, 1998. That is the bad news. In fact, despite all the rhetoric surrounding the major role assigned to education, the reality is that it is still struggling in the midst of a fundamental shift. The good news is that the cliché has a good chance to become more and more tangible among educators, materials designers and policy makers, who are starting to realise that in today’s Knowledge Era to think [critically] represents an asset which drastically shifts the traditional paradigms of power. Without a doubt, a learning environment which gives priority to the training of skills aiming at making students become critical thinkers can create and strengthen vantages of independence and autonomy for the students/future citizens belonging to that environment. “The proper business of school is to teach students to think!” has been the most widespread cliché in education over the last two decades (Squire, 1983; Paris, Lipson & Wixson, 1983; Spires et alli, 1993; Littlewood, 1996; Collins, 1998; Yang, 1998; Shneiderman, 1998. That is the bad news. In fact, despite all the rhetoric surrounding the major role assigned to education, the reality is that it is still struggling in the midst of a fundamental shift. The good news is that the cliché has a good chance to become more and more tangible among educators, materials designers and policy makers, who are starting to realise that in today’s Knowledge Era to think [critically] represents an asset which drastically shifts the traditional paradigms of power. Without a doubt, a learning environment which gives priority to the training of skills aiming at making students become critical thinkers can create and strengthen vantages of
Lee, Adeline; Coles, Jan; Lee, Stuart J; Kulkarni, Jayashri
Rates of disclosure of child abuse by women survivors are low, and general practitioners seldom ask women about such history. This study explored the experiences of women survivors: child abuse disclosure, GP service use and thoughts on being asked about their abuse experiences. A cross-sectional study containing quantitative and qualitative questions was conducted with 108 women child abuse survivors. Only 5% of the women disclosed their child abuse to their GP and 19% were asked about their child abuse history. More than half of the women (58%) asked reported feeling hopeful or relieved and none reported feeling offended. Rates of child abuse inquiry by GPs and disclosures by women survivors remain low. With the majority of women survivors reporting feeling relieved and none offended when asked about their child abuse experiences, GPs should consider asking women who present to their practice about such experiences: This may facilitate early intervention.
Stolzenberg, Stacia N; McWilliams, Kelly; Lyon, Thomas D
Children's potential confusion between "ask" and "tell" can lead to misunderstandings when child witnesses are asked to report prior conversations. The verbs distinguish both between interrogating and informing, and between requesting and commanding. Children's understanding was examined using both field (Study 1) and laboratory methods (Studies 2-4). Study 1 examined 100 5- to 12-year-olds' trial testimony in child sexual abuse cases, and found that potentially ambiguous use of ask and tell was common, typically found in yes-no questions that elicited unelaborated answers, and virtually never clarified by attorneys or child witnesses. Studies 2 to 4 examined 345 maltreated 6- to 11-year-olds' understanding of ask and tell. The results suggest that children initially comprehend telling as saying, and thus believed that asking is a form of telling. As such, they often endorsed asking as telling when asked yes-no questions, but distinguished between asking and telling when explicitly asked to choose. Their performance was impaired by movement between different use of the words. Child witnesses' characterization of their conversations can easily be misconstrued by the way in which they are questioned, leading questioners to misinterpret whether they were coached by disclosure recipients or coerced by abuse suspects. (PsycINFO Database Record (c) 2017 APA, all rights reserved).
Salam, Noor Efni; Elza, Putri
The development of technology in communication raises the growth of social networking sites that Ask.fm now becomes a popular social network that is loved by many people everywhere, especially in Pekanbaru. The use of social networking Ask.fm as a virtual communication media raises various meanings associated with the reasons why they choose to use the Ask.fm as a social network they use. This study aims to determine the motive, meaning features Ask.fm, and the meaning of friendship on the us...
Mukenge-Tshibaka, Léonard; Alary, Michel; Geraldo, Nassirou; Lowndes, Catherine M
Our objective was to assess if female sex workers (FSWs) and their potential male clients in Cotonou, Benin, know how to use male condoms correctly. From April to June 2000, 314 FSWs and 208 men were interviewed, and asked to demonstrate on a wooden penis how they usually use male condoms. In all, 27.6% of both women and men tore the condom envelope on the notch; 89.3% of the women versus 75.4% of the men easily found the correct side; 17.3% of the women versus 28.3% of the men held the top of the condom to avoid air entering; 91.4% of the women versus 75.6% of the men correctly unrolled the condom. Taking all the four criteria together, only approximately 11% of participants performed a correct condom use demonstration. FSWs frequently reported condom breakage, which was significantly associated with incorrect condom demonstration (P = 0.04). Correct condom use is suboptimal in these heavy consumers of male condoms in Benin. Condom breakage is frequent and is associated with incorrect use.
Opree, Suzanna J; Buijzen, Moniek; Valkenburg, Patti M
Research among adults suggests that materialism and life satisfaction negatively influence each other, causing a downward spiral. So far, cross-sectional research among children has indicated that materialistic children are less happy, but causality remains uncertain. This study adds to the literature by investigating the longitudinal relation between materialism and life satisfaction. We also investigated whether their relation depended on children's level of exposure to advertising. A sample of 466 children (aged 8-11; 55% girls) participated in a 2-wave online survey with a 1-year interval. We asked children questions about material possessions, life satisfaction, and advertising. We used structural equation modeling to study the relationship between these variables. For the children in our sample, no effect of materialism on life satisfaction was observed. However, life satisfaction did have a negative effect on materialism. Exposure to advertising facilitated this effect: We only found an effect of life satisfaction on materialism for children who were frequently exposed to advertising. Among 8- to 11-year-old children, life satisfaction leads to decreased materialism and not the other way around. However, this effect only holds for children who are frequently exposed to television advertising. It is plausible that the material values portrayed in advertising teach children that material possessions are a way to cope with decreased life satisfaction. It is important to reduce this effect, because findings among adults suggest that materialistic children may become less happy later in life. Various intervention strategies are discussed.
Henderson, Jillian T; Yu, Jean M; Harper, Cynthia C; Sawaya, George F
With newer recommendations for less frequent cervical cancer screening, longer intervals between routine gynecologic examinations might also be considered. A nationally representative mailed survey of U.S. obstetrician-gynecologists (n=521, response rate 62%) was conducted in 2010-11. Clinicians were asked their views on annual gynecologic examinations and on the consequences of extending the interval from annually to every 3 years for asymptomatic patients. Over two-thirds considered annual gynecologic examination very important for women in their reproductive years (69%); fewer consider it very important for women in menopause (55%). Most anticipated that shifting examinations to every 3 years would result in lower patient satisfaction (78%), contraceptive provision (74%), and patient health and well-being (74%). Decreases in clinic volume (93%) and financial reimbursement (78%) were also expected. Anticipated effects of longer intervals varied by provider characteristics, geography, and practice setting. Obstetrician-gynecologists in the U.S. believed that longer intervals between routine examinations would have negative repercussions for patients and medical practice, but there were differences by region, practice, and personal characteristics. Redefining annual gynecologic visits as contraceptive counseling and health maintenance visits could address financial and patient volume concerns, and perspectives from patients and other providers might reveal possible benefits of less frequent gynecologic examinations. Copyright © 2014 Elsevier Inc. All rights reserved.
OBJECTIVES: To compare injury patterns in children with many and few emergency department (ED) visits in order to reveal the causes for the frequent visits. METHODS: Three cohorts of Danish children (total 579 721 children) were followed for three years when their ages were 0-2, 6-8, and 12......-14 years. Information on all ED visits was obtained from the Danish National Patient Registry. Injury type, place of accident, injury mechanism, admission, and distance to ED were compared between children with frequent ED visits (five or more during the three years) and children with only one visit....... RESULTS: Children with frequent visits had a different injury pattern with 0-46% more superficial injuries and 25-82% more dislocations, sprains, and strains. There was 20-30% fewer fractures and 12% fewer falls from a higher level. 15-51% fewer were admitted. CONCLUSIONS: Children with many ED visits had...
Landex, Alex; Kaas, Anders H.
The examination of operation quality for high-frequent operation requires other approaches than the typical evaluation of punctuality (trains on time) and reliability (operated trains). This is because passengers in high-frequent railway systems do not necessarily notice train delays as they just...... take the first train in their direction. The article examines four different approaches to examine operation quality for high-frequent operation that are based on the experiences of the passengers. These approaches are the service frequency of the operation, travel time extension, a combination...... of the service frequency and travel time approaches, and passenger delays. The service frequency and travel time approaches are simple measurements with low complexity and complement each other. Therefore, the article recommends combining the service frequency and travel time approaches to get a more accurate...
This article reports the frequency of the use of coping scales in academic journals published from 1998 to 2010. Two thousand empirical journal articles were selected from the EBSCO database. The COPE, Ways of Coping Questionnaire, Coping Strategies Questionnaire, Coping Inventory for Stressful Situations, Religious-COPE and Coping Response Inventory were frequently mentioned. In particular, the COPE (20.2%) and Ways of Coping Questionnaire (13.6%) were used the most frequently. In this literature reviewed, coping scales were most often used to assess coping with health issues (e.g. illness, pain and medical diagnoses) over other types of stressors, and patients were the most frequent participants. Further, alpha coefficients were estimated for the COPE subscales, and correlations between the COPE subscales and coping outcomes were calculated, including depressive symptoms, anxiety, negative affect, psychological distress, physical symptoms and well-being. Copyright © 2013 John Wiley & Sons, Ltd.
Aagaard, Jørgen; Aagaard, Andreas; Buus, Niels
and social support. RESULTS: The study identified two overall trends of predictors of frequent use of the psychiatric emergency room. High use of psychiatric services: ≥5 visits to the psychiatric emergency room, ≥3 admissions or ≥60 bed days during the year, was and continued to be predictive of high use...... to psychiatric emergency services. OBJECTIVES: To identify predictors of frequent use of a psychiatric emergency room at a Danish University Psychiatric Hospital through a 12-year period (1995-2007) and to speculate on how changes in the mental healthcare services affect predictors of frequent use through time....... DESIGN: A large-scale register based logistic regression analysis combined with a small-scale explorative, interpretative interview study. Register data were drawn from the Danish Central Psychiatric Research Register. Four-year cohorts (1995, 1998, 2001 and 2004) of patients with at least one visit...
Vedsted, Peter; Olesen, Frede
BACKGROUND: A lack of social support is associated with increased morbidity and mortality and a decreased effect of prevention. Frequent attenders to primary care are characterised by poorer social conditions than other patients in general practice, but we do not know whether this is due to social...... inequalities in health or whether social factors in themselves determine the use of general practice. AIM: To examine if social factors are associated with frequent attendance in general practice after adjusting for physical and psychological health variables. DESIGN OF STUDY: Population-based cross...... during the period November 1997-October 1998. A questionnaire about physical, psychological and social factors was sent to the patients. The associations between social factors and frequent attendance were adjusted for physical and psychological health and tendency towards somatisation. RESULTS: A total...
Schmoll, S; Boyer, L; Henry, J-M; Belzeaux, R
Frequent visitors of psychiatric emergency wards are an important health care problem. Previous studies underlined that 2 % to 9 % of patients induce 15 % to 33 % of total clinical activity. Those patients have chronic and severe mental illness such as schizophrenia, associated with social and financial difficulties. The aim of this study was to describe demographic and clinical characteristics of frequent visitors to a psychiatric emergency ward in a French Academic hospital over 6years in comparison to non-frequent visitors. The study is based on a retrospective review of the psychiatric emergency wards' administrative and medical computer databases; data that included demographic, financial, clinical, and management information. During this 6-year study, the psychiatric ward recorded 16,754 care episodes for 8800 different patients. We compared frequent visitors with other visitors using univariate and multivariate analyses. Frequent visitors were defined by a number of visits greater than 2 of the mean standard deviation. Two percent of patients (n=192) had nine or more visits during the period. These patients caused 21 % of the total number of the visits. In the univariate analysis, the most significant reasons for referral in frequent visitors versus others (Phomeless (OR=2.7, IC: 1.8-4). Factors associated with non-frequent visitors were mood disorders (OR=0.07, IC: 0.03-0.19) and neurotic, stress-related, and somatoform disorders (OR=0.14, IC: 0.05-0.4). Sex and age were not significant in multivariate analysis. This study identifies significant demographic and clinical factors associated with frequent visits in psychiatric emergency ward in accordance with the large majority of previous studies. We found that psychotic disorders or schizophrenia were the main diagnosis of these patients. Moreover, precariousness (homeless, financial assistance) is an important demographic factor associated with recurrence. However, contrary to numerous studies, we found no
Laruelle, Ph.; Snegaroff, Th.; Moreau, S.; Tellenne, C.; Brunel, S.
Fourth chapter of the book on the geo-policy of the sustainable development, this chapter deal with the different and international policies concerned by the problem. The authors analyze the american energy attitude and policy, the economical equilibrium facing the environmental equilibrium for the european policy, the sanctified and sacrificed nature and the japanese attitude, India and China, the great fear of the 21 century and the sustainable development in Africa. (A.L.B.)
A study was carried out to establish the presence of Cryptococcus neoformans and Candida species in two pigeon-frequented areas; garbage piles from two separate sites in Nairobi, and dog faeces from Small animal clinic, University of Nairobi, Kabete. The sampling included both solid materials and air. Potato Dextrose ...
Conwell, Marilyn; And Others
The following articles are presented in the section of the Northeast Conference Report on less frequently taught languages: (1) "American Sign Language," by M. Conwell and A. Nelson; (2) "Chinese," by D. Gidman; (3) "Japanese," by J. P. Berwald and T. Phipps; (4) "Latin," by M. Cleary; (5) "Portuguese," by R. Pedro Carvalho; and (6) "Russian," by…
DeSimone, Jeffrey S.
Reinforcing earlier findings from other data, college senior fraternity/sorority members are more likely to consume alcohol frequently. Large reductions in estimates upon controlling for time spent partying, and to a lesser extent cigarette use and intramural sports involvement, suggest considerable unobserved heterogeneity in the relationship.…
Farr, Sherry L; Curtis, Kathryn M; Robbins, Cheryl L; Zapata, Lauren B; Dietz, Patricia M
This study examines whether a woman's mental health is associated with use of contraception. We used national data from 2004 and 2006 to calculate the prevalence of contraceptive use among women with frequent mental distress. We examined associations among mental distress and permanent contraception and any highly or moderately effective, reversible contraceptive method. Women with (86%) and without (87%) frequent mental distress reported using contraception, but contraceptive type varied by mental distress and income. Among women who use contraception, those with frequent mental distress had 1.4 times higher odds (95% CI: 1.2-1.6) of using permanent contraception. Among lower income women who use reversible contraception, those with frequent mental distress had lower odds of using highly [adjusted odds ratio (aOR)=0.5, 95% CI: 0.4-0.8] and moderately (aOR=0.6, 95% CI: 0.4-0.9) effective methods than less effective methods. Contraceptive providers should consider mental health when providing counseling about contraception. Published by Elsevier Inc.
This study aimed at establishing occurrences of chest pains and frequent coughing among different classes of residents within Selebi Phikwe, Botswana where there are on going nickel-copper (Ni-Cu) mining and smelting activities. Through the administration of questionnaires and structured questions to 600 individuals, ...
Dang, Xuan-Hong; Ong, Kok-Leong; Lee, Vincent
We consider a CPU constrained environment for finding approximation of frequent sets in data streams using the landmark window. Our algorithm can detect overload situations, i.e., breaching the CPU capacity, and sheds data in the stream to “keep up”. This is done within a controlled error threshold...
This paper investigated a large number of errors found in the topic-based writings of Chinese EFL learners, especially provided an analysis on frequent errors, to find useful pedagogical implications for English grammar teaching and writing instruction in Chinese EFL setting. Students' topic-based writings were examined by the author. The findings…
Lopez-Castroman, Jorge; Perez-Rodriguez, Maria de las Mercedes; Jaussent, Isabelle; Alegria, Analucia A; Artes-Rodriguez, Antonio; Freed, Peter; Guillaume, Sébastien; Jollant, Fabrice; Leiva-Murillo, Jose Miguel; Malafosse, Alain; Oquendo, Maria A; de Prado-Cumplido, Mario; Saiz-Ruiz, Jeronimo; Baca-Garcia, Enrique; Courtet, Philippe
In spite of the high prevalence of suicide behaviours and the magnitude of the resultant burden, little is known about why individuals reattempt. We aim to investigate the relationships between clinical risk factors and the repetition of suicidal attempts. 1349 suicide attempters were consecutively recruited in the Emergency Room (ER) of two academic hospitals in France and Spain. Patients were extensively assessed and demographic and clinical data obtained. Data mining was used to determine the minimal number of variables that blinded the rest in relation to the number of suicide attempts. Using this set, a probabilistic graph ranking relationships with the target variable was constructed. The most common diagnoses among suicide attempters were affective disorders, followed by anxiety disorders. Risk of frequent suicide attempt was highest among middle-aged subjects, and diminished progressively with advancing age of onset at first attempt. Anxiety disorders significantly increased the risk of presenting frequent suicide attempts. Pathway analysis also indicated that frequent suicide attempts were linked to greater odds for alcohol and substance abuse disorders and more intensive treatment. Novel statistical methods found several clinical features that were associated with a history of frequent suicide attempts. The identified pathways may promote new hypothesis-driven studies of suicide attempts and preventive strategies. Copyright © 2010 Elsevier Ltd. All rights reserved.
Grønbæk, Karin Elmegård; Ralfkiaer, U.; Dahl, C.
Allelic loss at chromosome 9q31-34 is a frequent event in many lymphoproliferative malignancies. Here, we examined DBC1 at 9q33.1 as a potential target in lymphomagenesis. DBC1 is a putative tumor suppressor that has been shown to be involved in the regulation of cell growth and programmed cell d...
Perlman, Baron; McCann, Lee I.
Explores the most frequently listed undergraduate psychology courses for four institutional types by analyzing 400 college catalogs. Reports that some segmentation continues in the research methodology and developmental areas, the balance of natural and social science courses appear stable, and there are no signs of a change toward vocationalism.…
El Saeedy, Mohammed El Sayed
Mining frequent subgraphs is an important operation on graphs. Most existing work assumes a database of many small graphs, but modern applications, such as social networks, citation graphs or protein-protein interaction in bioinformatics, are modeled as a single large graph. Interesting interactions in such applications may be transitive (e.g., friend of a friend). Existing methods, however, search for frequent isomorphic (i.e., exact match) subgraphs and cannot discover many useful patterns. In this paper we propose GRAMI, a framework that generalizes frequent subgraph mining in a large single graph. GRAMI discovers frequent patterns. A pattern is a graph where edges are generalized to distance-constrained paths. Depending on the definition of the distance function, many instantiations of the framework are possible. Both directed and undirected graphs, as well as multiple labels per vertex, are supported. We developed an efficient implementation of the framework that models the frequency resolution phase as a constraint satisfaction problem, in order to avoid the costly enumeration of all instances of each pattern in the graph. We also implemented CGRAMI, a version that supports structural and semantic constraints; and AGRAMI, an approximate version that supports very large graphs. Our experiments on real data demonstrate that our framework is up to 3 orders of magnitude faster and discovers more interesting patterns than existing approaches.
Frequent visitors at the psychiatric emergency room (PER) constitute a small subgroup of patients, yet they are responsible for a disproportionate number of visits and thus claim considerable resources. Their needs are often left unmet and their repetitive visits reflect their dissatisfaction as well as that of PERs' staff. Motivated by these dilemmas, this study systematically reviews the literature about frequent visitors at PER and seeks to answer two questions: What characterizes frequent visitors at PER in the literature? and What characterizes PER in the literature? Based on 29 studies, this paper offers answers to the two questions based on a strength weakness opportunities and threats (SWOT) analysis. The results of the review and subsequent analysis of the literature revealed the multiplicity and complexity of frequent visitors' characteristics and how they appear to converge. Commonalities were more difficult to identify in PER characteristics. In some cases, this happened because the characteristics were poorly described or were context specific. As a result, it was not easy to compare the studies on PER. Based on SWOT and the findings of the analysis, the paper proposes new venues of research and suggests how the field of mental health might develop by taking into account its opportunities and threats.
Weinstein, Suzanne E.; Wu, Shao-Wei
This study compares the effectiveness of two different assessment techniques; readiness assessment tests (RATs) and frequent quizzing. We report student perceptions of the impact of these techniques on the number of readings done prior to the class period, thorough reading of assignments, ability to follow class discussions, ability to participate…
Suzuki, H; Toyota, M; Caraway, H; Gabrielson, E; Ohmura, T; Fujikane, T; Nishikawa, N; Sogabe, Y; Nojima, M; Sonoda, T; Mori, M; Hirata, K; Imai, K; Shinomura, Y; Baylin, S B; Tokino, T
Although mutation of APC or CTNNB1 (β-catenin) is rare in breast cancer, activation of Wnt signalling is nonetheless thought to play an important role in breast tumorigenesis, and epigenetic silencing of Wnt antagonist genes, including the secreted frizzled-related protein (SFRP) and Dickkopf (DKK) families, has been observed in various tumours. In breast cancer, frequent methylation and silencing of SFRP1 was recently documented; however, altered expression of other Wnt antagonist genes is largely unknown. In the present study, we found frequent methylation of SFRP family genes in breast cancer cell lines (SFRP1, 7 out of 11, 64%; SFRP2, 11 out of 11, 100%; SFRP5, 10 out of 11, 91%) and primary breast tumours (SFRP1, 31 out of 78, 40%; SFRP2, 60 out of 78, 77%; SFRP5, 55 out of 78, 71%). We also observed methylation of DKK1, although less frequently, in cell lines (3 out of 11, 27%) and primary tumours (15 out of 78, 19%). Breast cancer cell lines express various Wnt ligands, and overexpression of SFRPs inhibited cancer cell growth. In addition, overexpression of a β-catenin mutant and depletion of SFRP1 using small interfering RNA synergistically upregulated transcriptional activity of T-cell factor/lymphocyte enhancer factor. Our results confirm the frequent methylation and silencing of Wnt antagonist genes in breast cancer, and suggest that their loss of function contributes to activation of Wnt signalling in breast carcinogenesis. PMID:18283316
Smits, Frans T.; Brouwer, Henk J.; Zwinderman, Aeilko H.; van den Akker, Marjan; van Steenkiste, Ben; Mohrs, Jacob; Schene, Aart H.; van Weert, Henk C.; ter Riet, Gerben
Frequent attenders are patients who visit their general practitioner exceptionally frequently. Frequent attendance is usually transitory, but some frequent attenders become persistent. Clinically, prediction of persistent frequent attendance is useful to target treatment at underlying diseases or
Gregg A. Garn
Full Text Available When Republican legislators in Arizona failed to approve educational vouchers in four consecutive legislative sessions, a charter school program was approved as a compromise. The charter school policy was written during a special summer session and within three years, over 30,000 students were enrolled in 260 charter schools across the state. Republican policy makers, who failed to enact voucher legislation, proclaimed the charter school program to be an overwhelming success and protected it from amendments by Democrats and potential actions of bureaucrats that could have altered the policy intent. Research on the implementation of policy indicates that state and local implementors frequently undermine or alter legislative intentions. However, when Arizona policy makers approved the charter school policy, they overcame this persistent implementation phenomenon and, in fact, succeeded in preserving the legislative intentions in the working program. This policy study analyzes how they were able to achieve this elusive result. Key policy makers attended to four significant features of policy implementation in creating the charter school policy: communication, financial resources, implementor attitudes, and bureaucratic structure. Manipulating these key variables allowed policy makers to reduce implementation slippage.
Gerdes, A.; Heeren, B.J.; Jeuring, J.T.; Binsbergen, Thomas~van
Ask-Elle is a tutor for learning the higher-order, strongly-typed functional programming language Haskell. It supports the stepwise development of Haskell programs by verifying the correctness of incomplete programs, and by providing hints. Programming exercises are added to Ask-Elle by providing a
Describes a method of using newspaper articles in the English-language classroom called Read-Ask-and-Tell. The place of authentic materials in the classroom, including some of the pitfalls, are discussed. The Reading, Asking, and Telling components are outlined, and activities for consolidation and reinforcement of skills are suggested. Appendices…
Tokle, Torger; Serbay, M.; Rosenkranz, W.
32.1 Gbit/s InverseRZ-ASK-DQPSK is experimentally investigated using a new InverseRZ generation method. We demonstrate......32.1 Gbit/s InverseRZ-ASK-DQPSK is experimentally investigated using a new InverseRZ generation method. We demonstrate...
France, Bev; Bay, Jacquie L.
It was proposed that an analysis of the questions students anticipate asking, and ask, could provide information about an enculturation encounter between Year 13 biology students and scientists working in a biomedical-clinical research unit. As part of a day-long intervention at this research institute, small groups of students (10-15) met with…
Morton, Cory M.; Hoefinger, Heidi; Linn-Walton, Rebecca; Aikins, Ross; Falkin, Gregory P.
The current study analyzes a sample of questions about drugs asked online by youth who participated in the National Institute on Drug Abuse's (NIDA) "Drug Facts Chat Day." The types of drugs youth asked about were coded into 17 substance categories, and the topics they raised were coded into seven thematic categories. The top five…
Gerdes, Alex; Heeren, Bastiaan; Jeuring, J.T.; Binsbergen, Thomas van
Ask-Elle is a tutor for learning the higher-order, strongly-typed functional programming language Haskell. It supports the stepwise development of Haskell programs by verifying the correctness of incomplete programs, and by providing hints. Programming exercises are added to Ask-Elle by providing a
Lankes, R. David; Kasowitz, Abby S.
This Starter Kit is designed to help organizations and individuals who wish to offer human-mediated information services via the Internet to users in the K-12 community. A six-step process is proposed for organizations to follow in creating an "AskA" service. This process addresses all aspects involved in building and maintaining an AskA…
Song, Juhyun; Cheon, So Yeong; Lee, Won Taek; Park, Kyung Ah; Lee, Jong Eun
Apoptosis signal-regulating kinase-1 (ASK1) is the mitogen-activated protein kinase kinase kinase (MAPKKK) and participates in the various central nervous system (CNS) signaling pathways. In cerebral ischemia, vascular permeability in the brain is an important issue because regulation failure of it results in edema formation and blood-brain barrier (BBB) disruption. To determine the role of ASK1 on vascular permeability and edema formation following cerebral ischemia, we first investigated ASK1-related gene expression using microarray analyses of ischemic brain tissue. We then measured protein levels of ASK1 and vascular endothelial growth factor (VEGF) in brain endothelial cells after hypoxia injury. We also examined protein expression of ASK1 and VEGF, edema formation, and morphological alteration through cresyl violet staining in ischemic brain tissue using ASK1-small interference RNA (ASK1-siRNA). Finally, immunohistochemistry was performed to examine VEGF and aquaporin-1 (AQP-1) expression in ischemic brain injury. Based on our findings, we propose that ASK1 is a regulating factor of vascular permeability and edema formation in cerebral ischemia. Copyright © 2014 The Authors. Published by Elsevier B.V. All rights reserved.
Smith, Earl Justice
A female patient presented with erotomanic delusions of other female soldiers sexually harassing her and plotting to sexually assault her. On MRI, the patient was found to have numerous periventricular foci of signal changes extending into the deep white matter of both hemispheres. The MRI findings, along with lumbar puncture findings of oligoclonal bands in the cerebral spinal fluid, were consistent with a diagnosis of multiple sclerosis. After treatment with aripiprazole acutely and interferon beta-1a for several months, the patient experienced a decrease in her psychosis. The discussion of this case includes a brief overview of psychosis as a presenting symptom of multiple sclerosis, and also includes consideration of the patient's initial reluctance to seek treatment in light of the policy known colloquially as "don't ask, don't tell".
Allsep, L Michael
The image of the male warrior still dominates military culture, to the exclusion of women and homosexuals. Complicating the picture is a technological revolution that promises to widen the current gap between the myth and reality of the modern warrior even further. Nonetheless, despite long arguing that homosexuals were a direct threat to military culture and effectiveness, the Pentagon has largely treated the end of Don't Ask, Don't Tell as a policy matter. The difficulties still experienced by women in the armed services 40 years after they were first incorporated in significant numbers indicates that this response will be insufficient to address the deeper cultural issues. Gender issues implicate deeply held beliefs and values that persist even in the face of years of official admonishment and denial. Unless the military begins to transparently bridge the gap between the myth and reality of the modern warrior, military service without discrimination based on sexual orientation will remain an unachieved goal.
Full Text Available I provide a synthesis of the papers in the Special Issue, The Conservation and Restoration of Old Growth in Frequent-fire Forests of the American West. These papers - the product of an Old Growth Writing Workshop, held at Northern Arizona University in Flagstaff, Arizona on 18-19 April 2006 - represent the ideas of 25 workshop participants who argue for a new attitude toward managing old growth in the frequent-fire forests of the American West. Unlike the lush, old-growth rainforests of the Pacific Northwest, the dry, frequent-fire forests of the western United States evolved with surface fires that disturbed the system with such regularity that young trees were almost always killed. When saplings did survive, they grew beyond the harm of frequent surface fires and, ultimately, attained the characteristics that define old growth in these systems. This system worked well, producing old-growth trees in abundance, until the onset of Euro-American settlement in the mid- to late-19th century. The arrival of these settlers put in motion an interplay of unprecedented social, political, economic, and ecological forces (e.g., removal of Native Americans and their fire-based land management systems, overgrazing of the understory, aggressive logging, establishment of federal land management agencies, implementation of a federal fire suppression policy. These activities have culminated in 1 overly dense forested ecosystems that are now on the verge of collapse because of catastrophic fires (i.e., crown fire at the landscape level; the Rodeo-Chediski Fire and insect outbreaks, 2 the emergence of conservation-minded environmental legislation and policy, and 3 greater levels of interaction between citizens, federal agencies, and fire-prone landscapes. Recognizing the tenuous ecological situation of these forests, restoration ecologists, foresters, and others have developed ways to return historic ecological processes and lower tree densities to these forests
Cahill, Sean; Singal, Robbie; Grasso, Chris; King, Dana; Mayer, Kenneth; Baker, Kellan; Makadon, Harvey
Background The Institute of Medicine and The Joint Commission have recommended asking sexual orientation and gender identity (SOGI) questions in clinical settings and including such data in Electronic Health Records (EHRs). This is increasingly viewed as a critical step toward systematically documenting and addressing health disparities affecting lesbian, gay, bisexual, and transgender (LGBT) people. The U.S. government is currently considering whether to include SOGI data collection in the Stage 3 guidelines for the incentive program promoting meaningful use of EHR. However, some have questioned whether acceptable standard measures to collect SOGI data in clinical settings exist. Methods In order to better understand how a diverse group of patients would respond if SOGI questions were asked in primary care settings, 301 randomly selected patients receiving primary care at four health centers across the U.S. were asked SOGI questions and then asked follow-up questions. This sample was mainly heterosexual, racially diverse, and geographically and regionally broad. Results There was a strong consensus among patients surveyed about the importance of asking SOGI questions. Most of the LGBT respondents thought that the questions presented on the survey allowed them to accurately document their SOGI. Most respondents—heterosexual and LGBT—answered the questions, and said that they would answer such questions in the future. While there were some age-related differences, respondents of all ages overwhelmingly expressed support for asking SOGI questions and understood the importance of providers' knowing their patients' SOGI. Conclusions Given current deliberations within national health care regulatory bodies and the government's increased attention to LGBT health disparities, the finding that patients can and will answer SOGI questions has important implications for public policy. This study provides evidence that integrating SOGI data collection into the meaningful
Full Text Available The Institute of Medicine and The Joint Commission have recommended asking sexual orientation and gender identity (SOGI questions in clinical settings and including such data in Electronic Health Records (EHRs. This is increasingly viewed as a critical step toward systematically documenting and addressing health disparities affecting lesbian, gay, bisexual, and transgender (LGBT people. The U.S. government is currently considering whether to include SOGI data collection in the Stage 3 guidelines for the incentive program promoting meaningful use of EHR. However, some have questioned whether acceptable standard measures to collect SOGI data in clinical settings exist.In order to better understand how a diverse group of patients would respond if SOGI questions were asked in primary care settings, 301 randomly selected patients receiving primary care at four health centers across the U.S. were asked SOGI questions and then asked follow-up questions. This sample was mainly heterosexual, racially diverse, and geographically and regionally broad.There was a strong consensus among patients surveyed about the importance of asking SOGI questions. Most of the LGBT respondents thought that the questions presented on the survey allowed them to accurately document their SOGI. Most respondents--heterosexual and LGBT--answered the questions, and said that they would answer such questions in the future. While there were some age-related differences, respondents of all ages overwhelmingly expressed support for asking SOGI questions and understood the importance of providers' knowing their patients' SOGI.Given current deliberations within national health care regulatory bodies and the government's increased attention to LGBT health disparities, the finding that patients can and will answer SOGI questions has important implications for public policy. This study provides evidence that integrating SOGI data collection into the meaningful use requirements is both
Cahill, Sean; Singal, Robbie; Grasso, Chris; King, Dana; Mayer, Kenneth; Baker, Kellan; Makadon, Harvey
The Institute of Medicine and The Joint Commission have recommended asking sexual orientation and gender identity (SOGI) questions in clinical settings and including such data in Electronic Health Records (EHRs). This is increasingly viewed as a critical step toward systematically documenting and addressing health disparities affecting lesbian, gay, bisexual, and transgender (LGBT) people. The U.S. government is currently considering whether to include SOGI data collection in the Stage 3 guidelines for the incentive program promoting meaningful use of EHR. However, some have questioned whether acceptable standard measures to collect SOGI data in clinical settings exist. In order to better understand how a diverse group of patients would respond if SOGI questions were asked in primary care settings, 301 randomly selected patients receiving primary care at four health centers across the U.S. were asked SOGI questions and then asked follow-up questions. This sample was mainly heterosexual, racially diverse, and geographically and regionally broad. There was a strong consensus among patients surveyed about the importance of asking SOGI questions. Most of the LGBT respondents thought that the questions presented on the survey allowed them to accurately document their SOGI. Most respondents--heterosexual and LGBT--answered the questions, and said that they would answer such questions in the future. While there were some age-related differences, respondents of all ages overwhelmingly expressed support for asking SOGI questions and understood the importance of providers' knowing their patients' SOGI. Given current deliberations within national health care regulatory bodies and the government's increased attention to LGBT health disparities, the finding that patients can and will answer SOGI questions has important implications for public policy. This study provides evidence that integrating SOGI data collection into the meaningful use requirements is both acceptable to
Jørgensen, Jeanette Therming; Andersen, John Sahl; Tjønneland, Anne
.57-0.69, >4 years higher education vs. no vocational training) and employment (0.61; 0.57-0.65) were inversely associated with frequent attendance. Finally, obesity (1.54; 1.14-2.08), smoking (1.21; 1.12-1.30, current vs. never), physical activity (0.84; 0.80-89), alcohol consumption (0.83; 0.78-0.87 above vs....... below recommended level), and hormone therapy in women (1.52; 1.42-1.63) were all significant determinants of frequent attendance. CONCLUSIONS: In addition to pre-existing medical conditions, gender, socio-demographic and gender-specific factors, lifestyle (obesity, smoking, exercise and alcohol use...
Nichols, H J; Cant, M A; Hoffman, J I; Sanderson, J L
As breeding between relatives often results in inbreeding depression, inbreeding avoidance is widespread in the animal kingdom. However, inbreeding avoidance may entail fitness costs. For example, dispersal away from relatives may reduce survival. How these conflicting selection pressures are resolved is challenging to investigate, but theoretical models predict that inbreeding should occur frequently in some systems. Despite this, few studies have found evidence of regular incest in mammals, even in social species where relatives are spatio-temporally clustered and opportunities for inbreeding frequently arise. We used genetic parentage assignments together with relatedness data to quantify inbreeding rates in a wild population of banded mongooses, a cooperatively breeding carnivore. We show that females regularly conceive to close relatives, including fathers and brothers. We suggest that the costs of inbreeding avoidance may sometimes outweigh the benefits, even in cooperatively breeding species where strong within-group incest avoidance is considered to be the norm.
Full Text Available Continual data checking is considered as one of the most common search tools for frequent itemsets which requires storage on memory. On the other hand, according to properties of data stream which are unlimited productions with a high-speed, it is not possible saving these data on memory and we need for techniques which enables online processing and finding repetitive standards. One of the most popular techniques in this case is using sliding windows. The benefits of these windows can be reducing memory usage and also search acceleration. In this article, a new vertical display and an algorithm is provided based on the pins in order to find frequent itemsets in data streams. Since this new display has a compressed format itself so, the proposed algorithm in terms of memory consumption and processing is more efficient than any other similar algorithms.
Lim, Jung-Ah; Lee, Soon-Tae; Kim, Tae-Joon; Moon, Jangsup; Sunwoo, Jun-Sang; Byun, Jung-Ick; Jung, Keun-Hwa; Jung, Ki-Young; Chu, Kon; Lee, Sang Kun
The aim of this study was to analyze the clinical presentation and provocation factors of rhabdomyolysis in anti-NMDAR encephalitis. Among the 16 patients with anti-NMDAR encephalitis in our institutional cohort, nine patients had elevated CK enzyme levels and clinical evidence of rhabdomyolysis. Rhabdomyolysis was more frequent after immunotherapy. The use of dopamine receptor blocker (DRB) increased the risk of rhabdomyolysis. None of the patients without rhabdomyolysis received DRBs. Rhabdomyolysis is a frequent complication in anti-NMDAR encephalitis and more common after immunotherapy and the use of DRBs increases the risk. Therefore, DRBs should be administered carefully in patients with anti-NMDAR encephalitis. Copyright © 2016 Elsevier B.V. All rights reserved.
Frequent malaria in two patients on ART after stopping CPT 57. Malawi Medical Journal 29 (1): March 2017 http://dx.doi.org/10.4314/mmj.v29i1.12. Wongani J.S. Nyangulu1, Edson Mwinjiwa1, Titus H. Divala2, Randy G. Mungwira2,. Osward Nyirenda2, Maxwell Kanjala2, Gillian Mbambo3, Jane Mallewa4, Terrie E. Taylor2,.
Seth Bigelow; Michael C. Stambaugh; Joseph J. O' Brien; Andrew J. Larson; Michael A. Battaglia
To see a frequent-fire forest burn for the first time is to experience a remarkable teat of nature. Most people are accustomed to the slow change of forests with the seasons, not the instantaneous conversion of green and brown plant mass to smoke and char. Yet to visit such a forest a week after it bums is to see bright green shoots emerging, highlighted against a...
Lausch, Karen Rokkedal; Westh, Lena; Kristensen, Lena Hagelskjær; Lindberg, Jens; Tarp, Britta; Larsen, Carsten Schade
Rotavirus infection is the most common aetiology of acute gastroenteritis (AGE) among young children. In adults, diagnostics focus mainly on bacterial causes, though recent studies suggest that rotavirus is a frequent agent. The aim of this study was to examine the proportion of rotavirus in adults hospitalised with AGE and to identify possible predictors. During a 24-month period from 1 May 2010 adults (> 15 years) with AGE admitted to one of four hospitals in the Central Denmark Region were examined for rotavirus with VIKIA Rota-Adeno rapid test in addition to routine culture for bacterial pathogens. A total of 265 adult patients were included. 9.4% tested positive for rotavirus. Enteropathogenic bacteria were found in 24.5% of the cases. In the majority of cases (62.3%), no pathogen was found. Overall, rotavirus was the second-most frequent pathogen, exceeded only by Campylobacter spp. Immunosuppression and a C-reactive protein (CRP) below 50 mg/l (0-8 mg/l) were associated with rotavirus. The seasonality of rotavirus differed markedly from that of bacterial gastroenteritis. Rotavirus is the second-most frequently identified pathogen in adults hospitalised with AGE. Close contact to children or travel activity does not predict rotavirus gastroenteritis, but immunosuppression and a CRP below 50 mg/l do. The seasonality of rotavirus differs from that of bacterial gastroenteritis, making rotavirus the most frequently identified cause of AGE in adults admitted to hospital in the colder months. The trial was funded by an unrestricted grant from Sanofi Pasteur MSD. not relevant.
Kurpas, Donata; Szwamel, Katarzyna; Mroczek, Bożena
Governments struggle to fund health services and there is a growing interest in the cost, clinical characteristics, and interventions for high utilizers of care, such as persistent frequent attenders to primary care. The purpose of this study was to determine the components shaping the phenomenon of frequent attendance in patients with chronic respiratory diseases in primary care settings. We examined 200 adult patients with chronic diseases (median age 65, range 18-90) recruited from 126 general practitioners. We conclude that, in patients with chronic respiratory diseases, frequent attendance can be expected among those with a low level of satisfaction with their quality of health, a low level of QoL in the physical domain as much as QoL in the social relationships domain, making multiple visits to a doctor (more than 4 visits), taking more than five drugs, being treated for more than three chronic diseases, waiting at the doctor's office for no more than 30 min, receiving a greater number of primary care services, and requiring the assistance of a district nurse. Such patients may need social support interventions and monitoring of their clinical status.
Denisova, Evgeniya; Heidenreich, Barbara; Nagore, Eduardo; Rachakonda, P Sivaramakrishna; Hosen, Ismail; Akrap, Ivana; Traves, Víctor; García-Casado, Zaida; López-Guerrero, José Antonio; Requena, Celia; Sanmartin, Onofre; Serra-Guillén, Carlos; Llombart, Beatriz; Guillén, Carlos; Ferrando, Jose; Gimeno, Enrique; Nordheim, Alfred; Hemminki, Kari; Kumar, Rajiv
Recent reports suggested frequent occurrence of cancer associated somatic mutations within regulatory elements of the genome. Based on initial exome sequencing of 21 melanomas, we report frequent somatic mutations in skin cancers in a bidirectional promoter of diphthamide biosynthesis 3 (DPH3) and oxidoreductase NAD-binding domain containing 1 (OXNAD1) genes. The UV-signature mutations occurred at sites adjacent and within a binding motif for E-twenty six/ternary complex factors (Ets/TCF), at -8 and -9 bp from DPH3 transcription start site. Follow up screening of 586 different skin lesions showed that the DPH3 promoter mutations were present in melanocytic nevi (2/114; 2%), melanoma (30/304; 10%), basal cell carcinoma of skin (BCC; 57/137; 42%) and squamous cell carcinoma of skin (SCC; 12/31; 39%). Reporter assays carried out in one melanoma cell line for DPH3 and OXNAD1 orientations showed statistically significant increased promoter activity due to -8/-9CC > TT tandem mutations; although, no effect of the mutations on DPH3 and OXNAD1 transcription in tumors was observed. The results from this study show occurrence of frequent somatic non-coding mutations adjacent to a pre-existing binding site for Ets transcription factors within the directional promoter of DPH3 and OXNAD1 genes in three major skin cancers. The detected mutations displayed typical UV signature; however, the functionality of the mutations remains to be determined.
Frequent subgraph mining is a core graph operation used in many domains, such as graph data management and knowledge exploration, bioinformatics and security. Most existing techniques target static graphs. However, modern applications, such as social networks, utilize large evolving graphs. Mining these graphs using existing techniques is infeasible, due to the high computational cost. In this paper, we propose IncGM+, a fast incremental approach for continuous frequent subgraph mining problem on a single large evolving graph. We adapt the notion of “fringe” to the graph context, that is the set of subgraphs on the border between frequent and infrequent subgraphs. IncGM+ maintains fringe subgraphs and exploits them to prune the search space. To boost the efficiency, we propose an efficient index structure to maintain selected embeddings with minimal memory overhead. These embeddings are utilized to avoid redundant expensive subgraph isomorphism operations. Moreover, the proposed system supports batch updates. Using large real-world graphs, we experimentally verify that IncGM+ outperforms existing methods by up to three orders of magnitude, scales to much larger graphs and consumes less memory.
Prusak, Laurence (Editor); Cohen, Don (Editor); Ellis, Kerry (Editor); Kohut, Matt (Editor)
The topics covered include: The Summer of Hydrogen; Leading Your Leaders; Dawn: Cooperation, not Control; Best Buy: Planning for Disaster The Astronaut Glove Challenge: Big Innovation from a (Very) Small Team; Using the Space Glove to Teach Spatial Thinking; The Power of Story; Interview with Jay O'Callahan; Learning from Space Entrepreneurs; Featured Invention: Laser Scaling Device; Reaching for the APEX at Ames; The Project Manager Who Saved His Country; Choosing and Developing the Right Leadership Styles for Projects; and The Costs of Knowledge.
Cao, YongGang; Liu, Feifan; Simpson, Pippa; Antieau, Lamont; Bennett, Andrew; Cimino, James J; Ely, John; Yu, Hong
Clinical questions are often long and complex and take many forms. We have built a clinical question answering system named AskHERMES to perform robust semantic analysis on complex clinical questions and output question-focused extractive summaries as answers. This paper describes the system architecture and a preliminary evaluation of AskHERMES, which implements innovative approaches in question analysis, summarization, and answer presentation. Five types of resources were indexed in this system: MEDLINE abstracts, PubMed Central full-text articles, eMedicine documents, clinical guidelines and Wikipedia articles. We compared the AskHERMES system with Google (Google and Google Scholar) and UpToDate and asked physicians to score the three systems by ease of use, quality of answer, time spent, and overall performance. AskHERMES allows physicians to enter a question in a natural way with minimal query formulation and allows physicians to efficiently navigate among all the answer sentences to quickly meet their information needs. In contrast, physicians need to formulate queries to search for information in Google and UpToDate. The development of the AskHERMES system is still at an early stage, and the knowledge resource is limited compared with Google or UpToDate. Nevertheless, the evaluation results show that AskHERMES' performance is comparable to the other systems. In particular, when answering complex clinical questions, it demonstrates the potential to outperform both Google and UpToDate systems. AskHERMES, available at http://www.AskHERMES.org, has the potential to help physicians practice evidence-based medicine and improve the quality of patient care. Copyright © 2011 Elsevier Inc. All rights reserved.
Ball, Stephen J.
This paper identifies some new research issues and sketches out some new research questions for education policy and leadership researchers as a response to ongoing changes in the landscape of English education policy. Three interrelated issues are considered: leadership, values and interests, and ownership. It argues for the need to ask new…
Winton, Sue; Tuters, Stephanie
As the prevalence and negative effects of bullying become widely known, people around the world seem desperate to solve the bullying "problem". A sizeable body of research about many aspects of bullying and a plethora of anti-bullying programmes and policies now exist. This critical policy analysis asks: how does Ontario, Canada's…
Introduction: Health Policy and Systems Research and Analysis (HPSR&A) is an applied science that deals with complexity as it tries to provide lessons, tools and methods to understand and improve health systems and health policy. It is defined by the kinds of questions asked rather than a particular methodology.
presumption.... And four, all provisions of the Uniform Code of Military Justice will be enforced in an even-handed manner as regards both heterosexuals and...service unless manifested by homosexual conduct.18 In addition, the definition of “sexual orientation” was modified: An abstract sexual preference for...abstract preference . Other sources define sexual “orientation” to include overt sexual behavior.20 Current regulations, therefore, are based on conduct
eat away attheir organizational pride like unseen termite damage·, at least this seems to be the .. consensus gathered from one on one...Roadmap of Political, Legal,Regulatory, and Organizational Steps to Equal Treatment." In Attitudes Aren’t Free; Thinking Deeply about Diversity in...Attitudes Aren’t Free; Thinking. Deeply about Diversity in the US Anned Forces, by James E Parco and David A Levy. Maxwell Air Force Base AL: Air
orientation define whether he or she is fit to serve the nation? Are heterosexuals more patriotic than homosexuals ? Are heterosexuals more effective in...2) Bisexual means a person who engages in, desires to engage in, or intends to engage in homosexual and heterosexual acts; and (3) A homosexual ...
Conde, Ana R; Martins, Ana P; Brito, Miguel
in cell differentiation and protection and has been proposed as a candidate tumour suppressor for brain and epithelial cancer. One study reported a loss of DMBT1 expression in 12.5% (5/40) of gastric cancer samples. Here, we examined in more detail DMBT1 protein and mRNA expression in 78 primary gastric...... preferentially take place in well-differentiated gastric carcinoma. However, an upregulation of DMBT1 expression is more frequently found across all gastric cancer types....
Full Text Available The effect of frequent examinations on the students' learning has had inconsistent results. This study aimed to assess the effectiveness of frequent announced quizzes on the learning of a representative sample of Iranian medical students.This experimental study was conducted among 37 fifth semester medical students who had taken the course in Protozoology and Helminthology, in which the same basic information were provided about different types of protozoa and worms. Initially, in the teaching of helminthology, ten routine sessions were handled with lectures and interactive questions and answers. Then at the beginning of the protozoology topic in the beginning of all of the next 9 sessions, the students were informed that they will have a quiz at the end of each session. At the end of the semester, the total scores of quizzes were compared with the mean final scores of protozoology and helminthology using paired t and repeated measure tests.The mean final scores of the protozoology lesson were not significantly different from that of the helminthology (10.45 ± 2.75 vs.11.25 ± 2.56 on the scale of 20, respectively, P=0.13. There was no significant difference in the mean score of the five quizzes compared with the mean final term score of protozoology. The overall mean scores in the helminthology lesson (11.25±2.56, protozoology lesson (10.45±2.75, and the quizzes (9.16 ± 3.55 were significantly different (P <0.0001.Frequent announced quizzes were not effective on increasing the medical students' motivation and learning.
Analy Marquardt de Matos
were a self-administered questionnaire designed in compliance with WHO recommendations and other valid questionnaires from similar studies. Anonymous confidential data collecting was assured. Adolescents who reported frequent alcohol drinking (at least every weekend were considered exposed. RESULTS: Frequent alcohol drinking was associated with the male gender; early consumption; little-known sexual partner; problems with other drugs in the family; living with a partner; own income; drug trafficking; consumption with friends, activities at school, motivations (anxiety, excitement/pleasure, and consequences (other drugs, fights, debts in work/school CONCLUSIONS: Knowledge of personal, interpersonal, family and environmental factors associated with alcohol use in adolescents should be considered in the implementation of school programs and public policies for alcohol use prevention focusing on behaviors that could minimize exposure to risk.
Carl E. Fiedler
Full Text Available There is no one-size-fits-all approach to managing frequent-fire, old-growth forests. However, there are general guidelines to follow: 1 set objectives for both structure (tree density, diameter distribution, tree species composition, spatial arrangement, amount of coarse woody debris and function (nutrient cycling, desired tree species regeneration; 2 prioritize treatments according to ecological, economic, and social needs and risks; 3 identify the potential treatments (natural fire, prescribed fire, silvicultural cutting that best meet the objectives and scale of the project; and 4 implement the treatment(s. We discuss each of these guidelines in this article.
Schutte, Tim; Tichelaar, Jelle; Nanayakkara, Prabath; Richir, Milan; van Agtmael, Michiel
Given the increasing healthcare costs of an ageing population, there is growing interest in rational prescribing, which takes costs of medication into account. We aimed to gain insight into the attitude to and knowledge of medication costs of medical students and doctors in daily practice. This was a cross-sectional electronic survey among medical students (bachelor/master) and doctors (consultants/registrars). Attitude to costs was evaluated using a cost-consciousness scale. In open questions, the participants estimated the cost of commonly prescribed (generic/non-generic) drugs (including separate pharmacy dispensing costs). They were asked where they could find information about drug costs. Overall, a reasonable cost-consciousness was found. Students were less conscious of the cost than were doctors (15.56 SD 3.25 versus 17.81 SD 2.25; scale 0-24; p = 0.001). In contrast to this consciousness, actual estimated drug costs were within a 25% margin for only 5.4% of generic and 13.7% of proprietary drugs (Wilcoxon signed-rank, p price of generic drugs was frequently overestimated (77.5%) and that of proprietary drugs was underestimated (51.4%). The dispensing costs were estimated correctly for 30% of the drugs. Most doctors (84%) and a minority of students (40%) were able to identify at least one source of information about drug costs. While doctors and students considered it important to be aware of the cost of drugs, this attitude is not reflected in their ability to estimate the cost of frequently prescribed drugs. Cost awareness is important in therapeutic reasoning and cost-effective prescribing. Both should be better addressed in (undergraduate) pharmacotherapy education. © 2016 The Authors. Basic & Clinical Pharmacology & Toxicology published by John Wiley & Sons Ltd on behalf of Nordic Association for the Publication of BCPT (former Nordic Pharmacological Society).
... (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM RECREATIONAL ENGINES AND VEHICLES Testing Production-Line Vehicles and Engines § 1051.335 How do I ask EPA to reinstate my suspended certificate? (a...
... Auditing § 1068.440 How do I ask EPA to reinstate my suspended certificate? (a) Send us a written report... failure, propose a remedy, and commit to a date for carrying it out. In your proposed remedy include any...
Full Text Available A number of studies investigated how financial information affected investment decisions. The study extendedthis line of research by examining the effect of risk, proxied by price per share, number of shareholders, numberof dealers, trading volume, accounting risk and market risk measures on the bid ask spread. Further, theresearch tried to test the relationship between bid ask spread and cost of equity capital. The samples of thisresearch were the manufacturing companies listed at Indonesian Stock Exchange which shared the dividendfor 3 years; there were 40 companies. Data analysis technique used multiple regression analysis. The results ofregression provided evidence of statistically significant effect of price per share, market value, asset size andprice variability on bid ask spread. At last, there was a positive relationship between bid ask spread and cost ofequity capital
as with national and sub-national governments in Europe, all of them introducing interesting novelties in their innovation policy. These changes refer to different aspects of policy, mainly the content of policy initiatives towards science, technology and innovation; the instruments governments are using...... to achieve their goals; and the actors in the policy system that are being mobilised in pursuing these goals. This paper deals with these policy changes, paying special attention to the novelties introduced since the early 1990s in Europe. The perspective of this paper deals mainly on the changes introduced...... at the EU level, and mentions similar trends taking place at national and sub-national levels. The questions that guide the contents here are essentially three, namely, what are the main traits of innovation policies in Europe since the 1990s and how have the EU and different national governments approached...
Lachman, Margie E; Agrigoroaei, Stefan; Murphy, Chandra; Tun, Patricia A
To test the hypothesis that frequent participation in cognitive activities can moderate the effects of limited education on cognitive functioning. A national study of adult development and aging, Midlife in the United States, with assessments conducted at the second wave of measurement in 2004-2006. Assessments were made over the telephone (cognitive measures) and in a mail questionnaire (demographic variables, measures of cognitive and physical activity, and self-rated health). A total of 3,343 men and women between the ages of 32 and 84 with a mean age of 55.99 years. The dependent variables were Episodic Memory (Immediate and Delayed Word List Recall) and Executive Functioning (Category Fluency, Backward Digit Span, Backward Counting Speed, Reasoning, and Attention Switching Speed). The independent variables were years of education and frequency of cognitive activity (reading, writing, doing word games or puzzles, and attending lectures). The covariates were age, sex, self-rated health, income, and frequency of physical activity. The two cognitive measures were regressed on education, cognitive activity frequency, and their interaction, while controlling for the covariates. Education and cognitive activity were significantly correlated with both cognitive abilities. The interaction of education and cognitive activity was significant for episodic memory but not for executive functioning. Those with lower education had lower cognitive functioning, but this was qualified by level of cognitive activity. For those with lower education, engaging frequently in cognitive activities showed significant compensatory benefits for episodic memory, which has promise for reducing social disparities in cognitive aging.
Shomura, Yusuke; Watanabe, Yoshinori; Yoshida, Kenichi
Abnormal traffic that causes various problems on the Internet, such as P2P flows, DDoS attacks, and Internet worms, is increasing; therefore, the importance of methods that identify and control abnormal traffic is also increasing. Though the application of frequent-itemset-mining techniques is a promising way to analyze Internet traffic, the huge amount of data on the Internet prevents such techniques from being effective. To overcome this problem, we have developed a simple frequent-itemset-mining method that uses only a small amount of memory but is effective even with the large volumes of data associated with broadband Internet traffic. Using our method also involves analyzing the number of distinct elements in the itemsets found, which helps identify abnormal traffic. We used a cache-based implementation of our method to analyze actual data on the Internet and demonstrated that such an implementation can be used to provide on-line analysis of data while using only a small amount of memory.
Boidi, María Fernanda; Queirolo, Rosario; Cruz, José Miguel
In 2013, Uruguay became the first country to fully regulate the cannabis market, which now operates under state control. Cannabis can be legally acquired in three ways: growing it for personal use (self-cultivation), cannabis club membership, and from pharmacies (not yet implemented). Users must be entered into a confidential official registry to gain access. This article presents findings of a Respondent Driven Sample survey of 294 high-frequency cannabis consumers in the Montevideo metropolitan area. Frequent consumers resort to more than one method for acquiring cannabis, with illegal means still predominating after 1 year of the new regulation law. Cannabis users overwhelmingly support the current regulation, but many of them are reluctant to register. Some of the attitudes and behaviors of the high-frequency consumers pose a challenge to the success of the cannabis law. Individuals relying on more than one method of access defy the single access clause, a prerequisite for legal use, while the maximum amount of cannabis individuals can access monthly seems too high even for most frequent consumers, which might promote the emergence of a grey market. Reluctance to register among a significant proportion of high-frequency consumers raises doubts about the law's ability to achieve its stated objectives. Copyright © 2016 Elsevier B.V. All rights reserved.
Popovska-Jovicić, Biljana; Canović, Predrag; Gajović, Olgica; Raković, Ivana; Mijailović, Zeljko
The differential diagnosis of fever of unknown origin (FUO) includes more than 200 different diseases and conditions. The aim of this study was to identify the most frequent causes of FUO among adult patients according to gender and age. The study included 74 patients examined from June 2010 to June 2013 at the Infectious Disease Clinic, Clinical Center Kragujevac in Serbia, according to the defined criteria for FUO. The patients were divided according to the diagnosis into four groups: infectious, malignant, rheumatic and "other diseases". A cause of febricity could not be estabilshed in a portion of subjects, and they comprised the group of undiagnosed cases. Infectious diseases were dominant in the study, followed by rheumatic diseases, which were most frequently found in women and the elderly. The diseases recognised as the most common causes of febricity were subacute thyroiditis, subacute endocarditis, Still's disease, rheumatic polymyalgia with or without temporal arteritis, and cytomegalovirus infection. In 44% of the patients, the final diagnosis was composed of only six clinical entities. The importance of establishing the diagnosis of rheumatic disease is especially emphasised, in line with other authors' research indicating the number of these diseases is on the rise. The diagnostic approach to FUO should always be directed to the known frequency of diseases.
Raven, Maria C; Carrier, Emily R; Lee, Joshua; Billings, John C; Marr, Mollie; Gourevitch, Marc N
Substance use (SU) disorders adversely impact health status and contribute to inappropriate health services use. This qualitative study sought to determine SU-related factors contributing to repeated hospitalizations and to identify opportunities for preventive interventions. Fifty Medicaid-insured inpatients identified by a validated statistical algorithm as being at high-risk for frequent hospitalizations were interviewed at an urban public hospital. Patient drug/alcohol history, experiences with medical, psychiatric and addiction treatment, and social factors contributing to readmission were evaluated. Three themes related to SU and frequent hospitalizations emerged: (a) barriers during hospitalization to planning long-term treatment and follow-up, (b) use of the hospital as a temporary solution to housing/family problems, and (c) unsuccessful SU aftercare following discharge. These data indicate that homelessness, brief lengths of stay complicating discharge planning, patient ambivalence regarding long-term treatment, and inadequate detox-to-rehab transfer resources compromise substance-using patients' likelihood of avoiding repeat hospitalization. Intervention targets included supportive housing, detox-to-rehab transportation, and postdischarge patient support.
Full Text Available Apoptosis signal-regulating kinase 1 (ASK1, a member of the MAPK kinase kinase kinase (MAP3K family, is activated by various stimuli, which include oxidative stress, endoplasmic reticulum (ER stress, calcium influx, DNA damage-inducing agents and receptor-mediated signaling through tumor necrosis factor receptor (TNFR. Inspiration of a high concentration of oxygen is a palliative therapy which counteracts hypoxemia caused by acute lung injury (ALI-induced pulmonary edema. However, animal experiments so far have shown that hyperoxia itself could exacerbate ALI through reactive oxygen species (ROS. Our previous data indicates that ASK1 plays a pivotal role in hyperoxia-induced acute lung injury (HALI. However, it is unclear whether or not deletion of ASK1 in vivo protects against HALI. In this study, we investigated whether ASK1 deletion would lead to attenuation of HALI. Our results show that ASK1 deletion in vivo significantly suppresses hyperoxia-induced elevation of inflammatory cytokines (i.e. IL-1β and TNF-α, cell apoptosis in the lung, and recruitment of immune cells. In summary, the results from the study suggest that deletion of ASK1 in mice significantly inhibits hyperoxic lung injury.
cation technology (ICT) and now. Minister of Science and Technology, was one of the architects of Mozam- bique's ICT policy in 2000 — the first in Africa. Nationwide access to these technologies is one of the pillars of the government's science and technology policy. “We don't believe in politicians, but we believe in politics.
Menendez, Mariano E; van Hoorn, Bastiaan T; Mackert, Michael; Donovan, Erin E; Chen, Neal C; Ring, David
In the midst of rapid expansion of medical knowledge and decision-support tools intended to benefit diverse patients, patients with limited health literacy (the ability to obtain, process, and understand information and services to make health decisions) will benefit from asking questions and engaging actively in their own care. But little is known regarding the relationship between health literacy and question-asking behavior during outpatient office visits. (1) Do patients with lower levels of health literacy ask fewer questions in general, and as stratified by types of questions? (2) What other patient characteristics are associated with the number of questions asked? (3) How often do surgeons prompt patients to ask questions during an office visit? We audio-recorded office visits of 84 patients visiting one of three orthopaedic hand surgeons for the first time. Patient questions were counted and coded using an adaptation of the Roter Interaction Analysis System in 11 categories: (1) therapeutic regimen; (2) medical condition; (3) lifestyle; (4) requests for services or medications; (5) psychosocial/feelings; (6) nonmedical/procedural; (7) asks for understanding; (8) asks for reassurance; (9) paraphrase/checks for understanding; (10) bid for repetition; and (11) personal remarks/social conversation. Directly after the visit, patients completed the Newest Vital Sign (NVS) health literacy test, a sociodemographic survey (including age, sex, race, work status, marital status, insurance status), and three Patient-Reported Outcomes Measurement Information System-based questionnaires: Upper-Extremity Function, Pain Interference, and Depression. The NVS scores were divided into limited (0-3) and adequate (4-6) health literacy as done by the tool's creators. We also assessed whether the surgeons prompted patients to ask questions during the encounter. Patients with limited health literacy asked fewer questions than patients with adequate health literacy (5 ± 4 versus 9
Isinger-Ekstrand, Anna; Therkildsen, Christina; Bernstein, Inge
The Wnt signaling pathway is frequently deranged in colorectal cancer and is a key target for future preventive and therapeutic approaches. Colorectal cancers associated with the hereditary nonpolyposis colorectal cancer (HNPCC) syndrome are characterized by wide-spread microsatellite instability......, but show few gross genomic alterations. We characterized expression of the Wnt signaling pathway markers β-catenin, E-cadherin, TCF-4, and PTEN using immunohistochemical staining in colorectal cancers from individuals with HNPCC. Reduced membranous staining for β-catenin was found in 64% and for E......% of the tumors. In summary, altered expression of target molecules in the Wnt signaling pathway was demonstrated in the vast majority of the HNPCC-associated tumors, which support deranged Wnt-signaling as a central tumorigenic mechanism also in MMR defective colorectal cancer....
Isinger-Ekstrand, Anna; Therkildsen, Christina; Bernstein, Inge
The Wnt signaling pathway is frequently deranged in colorectal cancer and is a key target for future preventive and therapeutic approaches. Colorectal cancers associated with the hereditary nonpolyposis colorectal cancer (HNPCC) syndrome are characterized by wide-spread microsatellite instability......, but show few gross genomic alterations. We characterized expression of the Wnt signaling pathway markers ß-catenin, E-cadherin, TCF-4, and PTEN using immunohistochemical staining in colorectal cancers from individuals with HNPCC. Reduced membranous staining for ß-catenin was found in 64% and for E......% of the tumors. In summary, altered expression of target molecules in the Wnt signaling pathway was demonstrated in the vast majority of the HNPCC-associated tumors, which support deranged Wnt-signaling as a central tumorigenic mechanism also in MMR defective colorectal cancer....
Oliveira, Mirna Fontenele de; Freitas, Maria Célia de
This study aimed at identifying the most frequent Nursing Diagnoses and propose interventions for women under critical care into a maternal intensive care unit in a public hospital in Fortaleza, CE, Brazil. Retrospective study conducted with women's hospital health records. Ten Nursing Diagnoses were elaborated, being four risk: risk of infection, risk of unbalance of liquids volume, risk of aspiration, risk of damaged skin integrity and six real: altered maternity, impaired physical mobility, anxiety and impaired verbal communication. For the referred Nursing Diagnoses, nursing interventions are proposed according to the link between NANDA, NIC and NOC. It was concluded that the use of ND is a necessary technology for the Nursing reality, as it makes possible the integral care.
Andersen, Claus Lindbjerg; Wiuf, Carsten; Kruhøffer, Mogens
, consisting of 17 normal mucosa and 66 adenocarcinoma samples. The transcriptional analysis revealed an unchanged expression level in areas with intact copy number, including regions with uniparental disomy, and a reduced expression level in the LOH regions representing factual losses (including 5q, 8p and 17......) and lymph node metastasis status (gain of 7q and 13q). Another subset of the identified alterations was shown to represent intratumor heterogeneity. In conclusion, we demonstrate that uniparental disomy is frequent in CRC, and identify genomic alterations associated with TP53 inactivation and lymph node...... LOH regions showed no evidence of a reduced copy number, indicating the presence of uniparental structures. The distribution of these structures was non-random, primarily involving 8q, 13q and 20q. This finding was supported by analysis of an independent set of array-based transcriptional profiles...
Chiecchio, Laura; Dagrada, Gian Paolo; White, Helen E; Towsend, Mark R; Protheroe, Rebecca K M; Cheung, Kan Luk; Stockley, David M; Orchard, Kim H; Cross, Nicholas C P; Harrison, Christine J; Ross, Fiona M
Plasma cell leukemia (PCL) is a rare form of monoclonal gammopathy, which can originate de novo or evolve from multiple myeloma (MM) as a terminal leukemic phase. Previous cytogenetic studies of PCL have reported the presence of complex karyotypes with involvement of multiple unidentified chromosomal regions. We report here the analysis of 12 PCL (10 primary and two secondary) by metaphase and FISH analysis combined with oligonucleotide array data (244 k, Agilent). Interphase-FISH results were compared with those from a series of 861 newly diagnosed patients with MM. Cytogenetic analysis was successful on 11 patients, all of whom showed clonal chromosomal abnormalities. Compared with MM, t(11;14)(q13;q32) (42% versus 15%; P = 0.027) and t(14;16)(q32;q23) (25% versus 4%; P = 0.010) were more frequent in PCL, although neither the specific partner chromosome involved in the IgH translocation nor the ploidy status predicted for survival. Chromosomes 1, 8, 13, and 16 showed the highest number of copy number alterations with 8q24 being the chromosomal region most frequently involved. In eight of 12 patients we found abnormalities (translocations, one amplification, small deletions, and duplications) that directly targeted or were very close to MYC. Only four of these changes were detected by routine FISH analysis using commercial probes with the others exclusively detected by arrays. Quantitative reverse transcription polymerase chain reaction demonstrated that these different abnormalities were associated with increased levels of MYC mRNA. We conclude that MYC dysregulation by complex mechanisms is one of the major molecular events in the oncogenesis of PCL.
Menéndez Granados, Nicolás; Vaquero Abellán, Manuel; Toledano Estepa, Manuel; Pérez Díaz, Manuel Modesto; Redondo Pedraza, Rosa
To describe the distribution of frequent attenders (FA) through the different primary care practices in Cordoba-Guadalquivir Health District (Córdoba, Spain). An ecological study was performed, including data from 2011 to 2015. Defining FA as those subjects who made12 or more appointments per year; independently analysed for nursing, general practice and paediatrics. Prevalence of frequent attendance and FA/professional ratio were used as dependent variables. Demographic characteristics from district population, number of health professionals and use of general facilities were also examinated. Aiming to understand FA distribution, primary health settings were classified according to facility size and environmental location (urban, suburban and rural). The mean prevalence for FA was 10.86% (0.5 SE) for nursing; general practice 21.70% (0.7 SE) and for paediatrics 16.96% (0.7 SE). FA/professional ratios for the different professional categories were: 101.07 (5.0 SE) for nursing, 239.74 (9.0 SE) for general practice and 159.54 (9.8 SE) for paediatrics. A major part of primary health care users make a high number of consultations. From this group, women overuse nursing and general practitioner services more compared to men. A higher prevalence of FAs was observed in smaller settings, in rural areas. Although taking the FAs:professional ratio as the bar, medium-size practices are more highly overused. Copyright © 2017 SESPAS. Publicado por Elsevier España, S.L.U. All rights reserved.
Bodenmann, Patrick; Baggio, Stéphanie; Iglesias, Katia; Althaus, Fabrice; Velonaki, Venetia-Sofia; Stucki, Stephanie; Ansermet, Corine; Paroz, Sophie; Trueb, Lionel; Hugli, Olivier; Griffin, Judith L; Daeppen, Jean-Bernard
vulnerable population, when taking into account all five dimensions of a conceptual framework of vulnerability. The predictive factors identified could be useful in the early detection of future frequent users, in order to address their specific needs and decrease vulnerability, a key priority for health care policy makers. Application of the conceptual framework in future research is warranted.
Hotta, Tracey A
Do you really need to have a policy and procedure in the office? Frequently they are seen sitting on the shelf, collecting dust. The answer is yes for a number of very important reasons. A policy and procedure manual is a tool to set guidelines and expectations on the basis of the mission and vision of the office. A well-written manual is a powerful training tool for new staff so they can get a feel for the office culture. Furthermore, it is a provincial or state legislative requirement that can reduce management's concern about potential legal issues or problems. If an office does not have a manual to set guidelines, the employees may be forced to make their own decisions to solve problems, which can often result in confusion, inconsistencies, and mistakes.
Kerker, Bonnie D; Storfer-Isser, Amy; Szilagyi, Moira; Stein, Ruth E K; Garner, Andrew S; O'Connor, Karen G; Hoagwood, Kimberly E; Horwitz, Sarah M
The stress associated with adverse childhood experiences (ACEs) has immediate and long-lasting effects. The objectives of this study were to examine 1) how often pediatricians ask patients' families about ACEs, 2) how familiar pediatricians are with the original ACE study, and 3) physician/practice characteristics, physicians' mental health training, and physicians' attitudes/beliefs that are associated with asking about ACEs. Data were collected from 302 nontrainee pediatricians exclusively practicing general pediatrics who completed the 2013 American Academy of Pediatrics Periodic Survey. Pediatricians indicated whether they usually, sometimes, or never inquired about or screened for 7 ACEs. Sample weights were used to reduce nonresponse bias. Weighted descriptive and logistic regression analyses were conducted. Only 4% of pediatricians usually asked about all 7 ACEs; 32% did not usually ask about any. Less than 11% of pediatricians reported being very or somewhat familiar with the ACE study. Pediatricians who screened/inquired about ACEs usually asked about maternal depression (46%) and parental separation/divorce (42%). Multivariable analyses showed that pediatricians had more than twice the odds of usually asking about ACEs if they disagreed that they have little effect on influencing positive parenting skills, disagreed that screening for social emotional risk factors within the family is beyond the scope of pediatricians, or were very interested in receiving further education on managing/treating mental health problems in children and adolescents. Few pediatricians ask about all ACEs. Pediatric training that emphasizes the importance of social/emotional risk factors may increase the identification of ACEs in pediatric primary care. Copyright © 2016 Academic Pediatric Association. Published by Elsevier Inc. All rights reserved.
Marsland, Madeleine J; Lazarus, Michelle D
Social media (SoMe) is increasingly used in higher education (HE) to access knowledge and enable global communication. The SoMe platform Twitter ® is particularly beneficial in these contexts because it is readily accessible, easily searchable (via hashtags) and global. Given these advantages, the twitter platform @AskAnatomist was created to foster a global weekly tweet chat, where students and academics can ask and address anatomy-related questions. The aim of this study was to identify themes arising in the early stages of the @AskAnatomy Twitter community to gain insights into current needs/key areas for academic anatomists, students, and other followers. A qualitative analysis of tweets including the hashtag #AnatQ, (the associated @AskAnatomist hashtag), was undertaken to achieve this aim. Thematic analysis revealed three core themes arising in the formative stages of the @AskAnatomist Twitter site: (1) anatomical education modalities, (2) specific anatomy content, and (3) research motivations. These themes reveal controversies within the field of anatomical sciences, areas for potential education resource improvement and research, as well as the humor of anatomists. Though the original intent of the @AskAnatomist site was to engage the general public in anatomy content and knowledge, tweet analysis suggests that academic anatomists were the primary active "tweeters". Interestingly, this analysis reveals that the @AskAnatomist site progressed into a web-based community of practice (CoP), suggesting an additional benefit of SoMe communities in the field of anatomy. © 2017 American Association of Anatomists.
Ren, Carina Bregnholm; Rasmussen, Rasmus Kjærgaard
planning and execution and of event outcomes beyond the narrow confines of bed nights and legacies. Second, we introduce policies as an entry point to unlock discussions and manifestations of value and futures which connect to AWG. In order to exemplify the workings of the AWG event in these domains, we...... present three central policy stories from the field. The stories tell of how the event was first interested, then activated and finally evaluated. Besides adding a new understanding to policy-driven events as a locus of value creation, we also argue that the AWG 2016 offer speculative bets for new...
Full Text Available Most federal legislation and policies (e.g., the Wilderness Act, Endangered Species Act, National Forest Management Act fail to speak directly to the need for old-growth protection, recruitment, and restoration on federal lands. Various policy and attitudinal barriers must be changed to move beyond the current situation. For example, in order to achieve the goal of healthy old growth in frequent-fire forests, the public must be educated regarding the evolutionary nature of these ecosystems and persuaded that collaborative action rather than preservation and litigation is the best course for the future of these forests. Land managers and policy makers must be encouraged to look beyond the single-species management paradigm toward managing natural processes, such as fire, so that ecosystems fall within the natural range of variability. They must also see that, given their recent evidence of catastrophic fires, management must take place outside the wildland-urban interface in order to protect old-growth forest attributes and human infrastructure. This means that, in some wilderness areas, management may be required. Land managers, researchers, and policy makers will also have to agree on a definition of old growth in frequent-fire landscapes; simply adopting a definition from the mesic Pacific Northwest will not work. Moreover, the culture within the federal agencies needs revamping to allow for more innovation, especially in terms of tree thinning and wildland fire use. Funding for comprehensive restoration treatments needs to be increased, and monitoring of the Healthy Forest Initiative and Healthy Forest Restoration Act must be undertaken.
Daniels, Jo; Osborn, Mike; Davis, Cara
Pain accounts for the majority of attendances to the Emergency Department (ED), with insufficient alleviation of symptoms resulting in repeated attendance. People who frequently attend the ED are typically considered to be psychologically and socially vulnerable in addition to experiencing health difficulties. This service development study was commissioned to identify the defining characteristics and unmet needs of frequent attenders (FAs) in a UK acute district general hospital ED, with a view to developing strategies to meet the needs of this group. A mixed-methods multi-pronged exploratory approach was used, involving staff interviews, focus groups, business data and case note analysis. Findings reflect an absence of a coherent approach to meeting the needs of FAs in the ED, especially those experiencing pain. FAs to this ED tend to be vulnerable, complex and report significant worry and anxiety. Elevated anxiety on the part of the patient may be contributing to a 'better safe than sorry' culture within the ED and is reported to bear some influence on the clinical decision-making process. It is recommended that a systemic approach is taken to improve the quality and accessibility of individualised care plans, provision of patient education, psychological care and implementation of policies and procedures. Change on an organisational level is likely to improve working culture, staff satisfaction and staff relationships with this vulnerable group of patients. A structured care pathway and supportive changes are likely to lead to economic benefits. Further research should build on findings to implement and test the efficacy of these interventions.
Adam, Taghreed; Hsu, Justine; de Savigny, Don; Lavis, John N; Røttingen, John-Arne; Bennett, Sara
In recent years, there have been several calls for rigorous health policy and systems research to inform efforts to strengthen health systems (HS) in low- and middle-income countries (LMICs), including the use of systems thinking concepts in designing and evaluating HS strengthening interventions. The objectives of this paper are to assess recent evaluations of HS strengthening interventions to examine the extent to which they ask a broader set of questions, and provide an appropriately comprehensive assessment of the effects of these interventions across the health system. A review of evaluations conducted in 2009-10 was performed to answer these questions. Out of 106 evaluations, less than half (43%) asked broad research questions to allow for a comprehensive assessment of the intervention's effects across multiple HS building blocks. Only half of the evaluations referred to a conceptual framework to guide their impact assessment. Overall, 24% and 9% conducted process and context evaluations, respectively, to answer the question of whether the intervention worked as intended, and if so, for whom, and under what circumstances. Almost half of the evaluations considered HS impact on one building block, while most interventions were complex targeting two or more building blocks. None incorporated evaluation designs that took into account the characteristics of complex adaptive systems such as non-linearity of effects or interactions between the HS building blocks. While we do not argue that all evaluations should be comprehensive, there is a need for more comprehensive evaluations of the wider range of the intervention's effects, when appropriate. Our findings suggest that the full range of barriers to more comprehensive evaluations need to be examined and, where appropriate, addressed. Possible barriers may include limited capacity, lack of funding, inadequate time frames, lack of demand from both researchers and research funders, or difficulties in undertaking this
ter Riet Gerben
Full Text Available Abstract Background General Practitioners spend a disproportionate amount of time on frequent attenders. So far, trials on the effect of interventions on frequent attenders have shown negative results. However, these trials were conducted in short-term frequent attenders. It would be more reasonable to target intervention at persistent frequent attenders. Typical characteristics of persistent frequent attenders, as opposed to 1-year frequent attenders and non-frequent attenders, may generate hypotheses regarding modifiable factors on which new randomized trials may be designed. Methods We used the data of all 28,860 adult patients from 5 primary healthcare centers. Frequent attenders were patients whose attendance rate ranked in the (age and sex adjusted top 10 percent during 1 year (1-year frequent attenders or 3 years (persistent frequent attenders. All other patients on the register over the 3-year period were referred to as non-frequent attenders. The lists of medical problems coded by the GP using the International Classification of Primary Care (ICPC were used to assess morbidity. First, we determined which proportion of 1-year frequent attenders was still a frequent attender during the next two consecutive years and calculated the GPs' workload for these patients. Second, we compared morbidity and number of prescriptions for non-frequent attenders, 1-year frequent attenders and persistent frequent attenders. Results Of all 1-year frequent attenders, 15.4% became a persistent frequent attender equal to 1.6% of all patients. The 1-year frequent attenders (3,045; 10.6% were responsible for 39% of the face-to-face consultations; the 470 patients who would become persistent frequent attenders (1.6% were responsible for 8% of all consultations in 2003. Persistent frequent attenders presented more social problems, more psychiatric problems and medically unexplained physical symptoms, but also more chronic somatic diseases (especially diabetes
Kristina M. Zierold
Full Text Available People living near environmental hazards may develop symptoms and health conditions that require specialized monitoring and treatment by healthcare providers. One emerging environmental hazard is coal ash. Coal ash is comprised of small particles containing heavy metals, polycyclic aromatic hydrocarbons, and radioactive elements. The overall purpose of this study was to explore whether healthcare providers ask patients if they live near an environmental hazard like coal ash storage sites and to assess what health conditions prompt a provider inquiry. Focus groups were conducted in 2012 and a cross-sectional survey was administered in 2013. Overall, 61% of survey respondents reported that their healthcare providers never asked if they lived near an environmental hazard. One focus group member stated “No, they don’t ask that. They just always blame stuff on you….” Respondents with asthma and other lung conditions were significantly more likely to be asked by a healthcare provider if they lived near an environmental hazard. Due to the unique exposures from environmental hazards and the low prevalence of patients being asked about environmental hazards, we recommend that healthcare providers take environmental health histories in order to understand patients’ exposures, to monitor symptoms of exposure, and to assist with education about reducing exposure.
Nones, Katia; Waddell, Nicola; Wayte, Nicci; Patch, Ann-Marie; Bailey, Peter; Newell, Felicity; Holmes, Oliver; Fink, J Lynn; Quinn, Michael C J; Tang, Yue Hang; Lampe, Guy; Quek, Kelly; Loffler, Kelly A; Manning, Suzanne; Idrisoglu, Senel; Miller, David; Xu, Qinying; Waddell, Nick; Wilson, Peter J; Bruxner, Timothy J C; Christ, Angelika N; Harliwong, Ivon; Nourse, Craig; Nourbakhsh, Ehsan; Anderson, Matthew; Kazakoff, Stephen; Leonard, Conrad; Wood, Scott; Simpson, Peter T; Reid, Lynne E; Krause, Lutz; Hussey, Damian J; Watson, David I; Lord, Reginald V; Nancarrow, Derek; Phillips, Wayne A; Gotley, David; Smithers, B Mark; Whiteman, David C; Hayward, Nicholas K; Campbell, Peter J; Pearson, John V; Grimmond, Sean M; Barbour, Andrew P
Oesophageal adenocarcinoma (EAC) incidence is rapidly increasing in Western countries. A better understanding of EAC underpins efforts to improve early detection and treatment outcomes. While large EAC exome sequencing efforts to date have found recurrent loss-of-function mutations, oncogenic driving events have been underrepresented. Here we use a combination of whole-genome sequencing (WGS) and single-nucleotide polymorphism-array profiling to show that genomic catastrophes are frequent in EAC, with almost a third (32%, n=40/123) undergoing chromothriptic events. WGS of 22 EAC cases show that catastrophes may lead to oncogene amplification through chromothripsis-derived double-minute chromosome formation (MYC and MDM2) or breakage-fusion-bridge (KRAS, MDM2 and RFC3). Telomere shortening is more prominent in EACs bearing localized complex rearrangements. Mutational signature analysis also confirms that extreme genomic instability in EAC can be driven by somatic BRCA2 mutations. These findings suggest that genomic catastrophes have a significant role in the malignant transformation of EAC.
Fernández Alonso, Cesáreo; Romero Pareja, Rodolfo; Rivas García, Aristides; Jiménez Gallego, Rosa; Majo Carbajo, Yolanda; Aguilar Mulet, Juan Mariano
To describe the characteristics of frequent users of hospital emergency departments and analyze whether characteristics varied in relation to how revisits were distributed over the course of the year studied. Retrospective study of patients over the age of 14 years who were treated in a hospital emergency department at least 10 times in 2013. Patients were identified in 17 public hospitals in the Spanish autonomous community of Madrid. Data related to the first and successive visits were gathered and analyzed by quarter year. We included 2340 patients with a mean (SD) age of 54 (21) years. A total of 1361 (58.%) were women, 1160 (50%) had no concomitant diseases, 1366 (58.2%) were substance abusers, and 25 (1.1%) were homeless. During the first visit, 2038 (87.1%) complained of a recent health problem, and 289 (12.4%) were admitted. Sixty (2.6%) patients concentrated their revisits in a single quarters 335 (14.3%) in 2 quarters, 914 (39.1%) in 3, and 1005 (42.9%) in 4. Patients whose revisits were distributed over more quarters were older (> 65 years), had more concomitant conditions, were on more medications (P women (P = .012) and more likely to have a specific diagnosis (P loyally comes to the same emergency department over the course of a year. Patients whose revisits are dispersed over a longer period have more complex problems and use more resources during their initial visit.
Higuera, P E; Brubaker, L B; Anderson, P M; Brown, T A; Kennedy, A T; Hu, F S
Understanding feedbacks between terrestrial and atmospheric systems is vital for predicting the consequences of global change, particularly in the rapidly changing Arctic. Fire is a key process in this context, but the consequences of altered fire regimes in tundra ecosystems are rarely considered, largely because tundra fires occur infrequently on the modern landscape. We present paleoecological data that indicate frequent tundra fires in northcentral Alaska between 14,000 and 10,000 years ago. Charcoal and pollen from lake sediments reveal that ancient birchdominated shrub tundra burned as often as modern boreal forests in the region, every 144 years on average (+/- 90 s.d.; n = 44). Although paleoclimate interpretations and data from modern tundra fires suggest that increased burning was aided by low effective moisture, vegetation cover clearly played a critical role in facilitating the paleo-fires by creating an abundance of fine fuels. These records suggest that greater fire activity will likely accompany temperature-related increases in shrub-dominated tundra predicted for the 21st century and beyond. Increased tundra burning will have broad impacts on physical and biological systems as well as land-atmosphere interactions in the Arctic, including the potential to release stored organic carbon to the atmosphere.
Liu, Chun-Hao; Lin, Sheng-Hsuan; Pan, Yuan-Chien; Lin, Yu-Hsuan
Abstract The aim of this study was to investigate the risk factors of smartphone addiction in high school students. A total of 880 adolescents were recruited from a vocational high school in Taiwan in January 2014 to complete a set of questionnaires, including the 10-item Smartphone Addiction Inventory, Chen Internet Addiction Scale, and a survey of content and patterns of personal smartphone use. Of those recruited, 689 students (646 male) aged 14 to 21 and who owned a smartphone completed the questionnaire. Multiple linear regression models were used to determine the variables associated with smartphone addiction. Smartphone gaming and frequent smartphone use were associated with smartphone addiction. Furthermore, both the smartphone gaming-predominant and gaming with multiple-applications groups showed a similar association with smartphone addiction. Gender, duration of owning a smartphone, and substance use were not associated with smartphone addiction. Our findings suggest that smartphone use patterns should be part of specific measures to prevent and intervene in cases of excessive smartphone use. PMID:27428191
Tsaponina, Olga; Haber, James E.
Summary Although repair of double-strand breaks (DSBs) by gene conversion is the most accurate way to repair such lesions, in budding yeast there is a thousand-fold increase in accompanying mutations, including interchromosomal template switches (ICTS) involving highly mismatched (homeologous) ectopic sequences. Although such events are rare and appear at a rate of 2×10−7 when template jumps occur between 71% identical sequences, they are surprisingly frequent (0.3% of all repair events) when the second template is identical to the first, revealing the remarkable instability of repair DNA synthesis. With homeologous donors, ICTS uses microhomologies as small as 2 bp. Cells lacking mismatch repair proteins Msh6 and Mlh1 form chimeric recombinants with two distinct patches of microhomology, implying that these proteins are crucial for strand discrimination of heteroduplex DNA formed during ICTS. We identify the chromatin remodeler Rdh54 as the first protein required for template switching that does not affect simple gene conversion. PMID:25066232
Full Text Available Chest pain is one of the most frequent patient’s complaints. The commonest underlying causes are well known, but, sometimes, in some clinical scenarios, it is necessary to consider other diagnoses. We report a case of a 68-year-old Caucasian male, chronically hypertensive, who complained of recurrent episodes of chest pain and fever with elevated acute phase reactants. The first investigation was negative for some of the most likely diagnosis and he quickly improved with anti-inflammatory drugs. Over a few months, his symptoms continued to recur periodically, his hypertension was aggravated, and he developed headaches and lower limbs claudication. After a temporal artery biopsy that was negative for vasculitis, he underwent a positron emission tomography suggestive of Takayasu Arteritis. Takayasu Arteritis is a rare chronic granulomatous vasculitis of the aorta and its first-order branches affecting mostly females up to 50 years old. Chest pain is experienced by >40% of the patients and results from the inflammation of the aorta, pulmonary artery, or coronaries.
Liu, Chun-Hao; Lin, Sheng-Hsuan; Pan, Yuan-Chien; Lin, Yu-Hsuan
The aim of this study was to investigate the risk factors of smartphone addiction in high school students.A total of 880 adolescents were recruited from a vocational high school in Taiwan in January 2014 to complete a set of questionnaires, including the 10-item Smartphone Addiction Inventory, Chen Internet Addiction Scale, and a survey of content and patterns of personal smartphone use. Of those recruited, 689 students (646 male) aged 14 to 21 and who owned a smartphone completed the questionnaire. Multiple linear regression models were used to determine the variables associated with smartphone addiction.Smartphone gaming and frequent smartphone use were associated with smartphone addiction. Furthermore, both the smartphone gaming-predominant and gaming with multiple-applications groups showed a similar association with smartphone addiction. Gender, duration of owning a smartphone, and substance use were not associated with smartphone addiction.Our findings suggest that smartphone use patterns should be part of specific measures to prevent and intervene in cases of excessive smartphone use.
Takasu, Michihiko; Kubota, Tetsuo; Tsuji, Takeshi; Kurahashi, Hirokazu; Numoto, Shingo; Watanabe, Kazuyoshi; Okumura, Akihisa
To clarify the semiology of febrile seizures (FS) and to determine the frequency of FS with symptoms suggestive of focal onset. FS symptoms in children were reported within 24h of seizure onset by the parents using a structured questionnaire consisting principally of closed-ended questions. We focused on events at seizure commencement, including changes in behavior and facial expression, and ocular and oral symptoms. We also investigated the autonomic and motor symptoms developing during seizures. The presence or absence of focal and limbic features was determined for each patient. The associations of certain focal and limbic features with patient characteristics were assessed. Information was obtained on FS in 106 children. Various events were recorded at seizure commencement. Behavioral changes were observed in 35 children, changes in facial expression in 53, ocular symptoms in 78, and oral symptoms in 90. In terms of events during seizures, autonomic symptoms were recognized in 78, and convulsive motor symptoms were recognized in 68 children. Focal features were evident in 81 children; 38 children had two or more such features. Limbic features were observed in 44 children, 9 of whom had two or more such features. There was no significant relationship between any patient characteristic and the numbers of focal or limbic features. The semiology of FS varied widely among children, and symptoms suggestive of focal onset were frequent. FS of focal onset may be more common than is generally thought. Copyright © 2017 Elsevier Inc. All rights reserved.
Tian, Hui; Yurchyshyn, Vasyl; Peter, Hardi; Solanki, Sami K.; Young, Peter R.; Ni, Lei; Cao, Wenda; Ji, Kaifan; Zhu, Yingjie; Zhang, Jingwen; Samanta, Tanmoy; Song, Yongliang; He, Jiansen; Wang, Linghua; Chen, Yajie
Solid evidence of magnetic reconnection is rarely reported within sunspots, the darkest regions with the strongest magnetic fields and lowest temperatures in the solar atmosphere. Using the world’s largest solar telescope, the 1.6 m Goode Solar Telescope, we detect prevalent reconnection through frequently occurring fine-scale jets in the Hα line wings at light bridges, the bright lanes that may divide the dark sunspot core into multiple parts. Many jets have an inverted Y-shape, shown by models to be typical of reconnection in a unipolar field environment. Simultaneous spectral imaging data from the Interface Region Imaging Spectrograph show that the reconnection drives bidirectional flows up to 200 km s‑1, and that the weakly ionized plasma is heated by at least an order of magnitude up to ∼80,000 K. Such highly dynamic reconnection jets and efficient heating should be properly accounted for in future modeling efforts of sunspots. Our observations also reveal that the surge-like activity previously reported above light bridges in some chromospheric passbands such as the Hα core has two components: the ever-present short surges likely to be related to the upward leakage of magnetoacoustic waves from the photosphere, and the occasionally occurring long and fast surges that are obviously caused by the intermittent reconnection jets.
Mladenovic, A.; Suput, J.S.; Ducman, V.; Skapin, A.S.
Lightweight aggregates (LWAs) are frequently used in concrete as well as in thermally insulating mortars and grouts, so that information on their alkali-silica reactivity (ASR) is very important. Four LWAs - expanded vermiculite, expanded clay, expanded glass and perlite - were studied regarding their ASR, using the following test methods: the accelerated mortar bar test (ASTM C 1260), the rapid chemical test (ASTM C 289) and the combined scanning electron microscopy-energy dispersive X-ray technique (SEM-EDX). According to these methods, neither the expanded vermiculite nor the expanded clay exhibited any potential ASR. On the other hand, in the case of the aggregates containing a glassy phase (expanded glass and perlite), the results of SEM-EDX analysis showed serious decomposition of aggregate texture due to ASR, although no deleterious expansion was observed in the accelerated mortar bar test. Therefore, suitable test criteria for ASR need to be defined for LWAs of this type when the AMBT method is used, as has already been suggested for slowly reactive aggregates in Australia
McCain, Kevin; Kampourakis, Kostas
Data from studies conducted to determine acceptance rates for evolution are often misleading. The questions that are asked and compared to one another do not always give an authentic picture of respondents' views. Quite often, polls, such as those by IPSOS, Gallup, and PEW, also run together questions asking respondents' beliefs in concepts like God with questions asking respondents' beliefs about concepts like evolution. The two are distinct and should not be confused. One might believe in evolution while having wrong beliefs about it, whereas someone else might decide not to believe in evolution while having accurate beliefs about it. Distinguishing between " belief in" and " belief about" might help remove an unrecognized confounding element from these studies.
Sivolodskii, E P
The chromogenic synthetic medium "Klebsiella 5-ASK CHROM-C was developedfor isolation and identification of klebsiellae of species of K. pneumoniae subsp. pneumoniae K. oxytoca, K. mobilis according chromogenic reaction to enzyme 5-aminosalycilate decarboxylase as a unique marker of genus Klebsiella. The L-proline and L-calcium glutamate are used as a source of nitrogen and carbon in medium. The consistency of composition of growth medium that ensure its regularity. The diagnostic sensitivity of chromogenic medium is 95.3 ± 1.7%; diagnostic specificity is 100%; analytical sensitivity is 1-2 colony-forming units per ml-1. The identification of Klebsiella is achieved simultaneously with their isolation during 24 = 48 hours. The test of 5-ASK decarboxylase using two chromogenic mediums "Klebsiella 5-ASK CHROM-C" permits identifying additionally K. pneumoniae subsp, ozaenae, K .pneumoniae subsp. Rhinoscleromatis.
Full Text Available A chipless RFID tag with unique ASK encoding technique is presented in this paper. The coding efficiency is enhanced regarding tag capacity. The amplitude varia¬tions of the backscattered RFID signal is used for encoding data instead of OOK. Strips of different widths are used to have amplitude variations. The ASK technique is applied using three different substrates of Kapton®HN, PET, and paper. To incorporate ASK technique, dual polarized rhombic shaped resonators are designed. These tags operate in the frequency range of 3.1–10.6 GHz with size of 70 × 42 mm^2. The presented tags are flexible and offer easy printability. The paper-based decomposable organic tag appears as an ultra low-cost solution for wide scale tracking. This feature enables them to secure a prominent position in the emerging fields of IoT and green electronics.
Liu, Meixian; Xu, Xianli; Wang, Kelin; Sun, Alexander Y; Liu, Wen; Zhang, Xiaoyan
Climate extremes have and will continue to cause severe damages to buildings and natural environments around the world. A full knowledge of the probability of the climate extremes is important for the management and mitigation of natural hazards. Based on Mann–Kendall trend test and copulas, this study investigated the characteristics of precipitation extremes as well as their implications in southwestern China (Yunnan, Guangxi and Guizhou Province), through analyzing the changing trends and probabilistic characteristics of six indices, including the consecutive dry days, consecutive wet days, annual total wet day precipitation, heavy precipitation days (R25), max 5 day precipitation amount (Rx5) and the rainy days (RDs). Results showed that the study area had generally become drier (regional mean annual precipitation decreased by 11.4 mm per decade) and experienced enhanced precipitation extremes in the past 60 years. Relatively higher risk of drought in Yuanan and flood in Guangxi was observed, respectively. However, the changing trends of the precipitation extremes were not spatially uniform: increasing risk of extreme wet events for Guangxi and Guizhou, and increasing probability of concurrent extreme wet and dry events for Yunnan. Meanwhile, trend analyses of the 10 year return levels of the selected indices implied that the severity of droughts decreased in Yunnan but increased significantly in Guangxi and Guizhou, and the severity of floods increased in Yunnan and Guangxi in the past decades. Hence, the policy-makers need to be aware of the different characterizations and the spatial heterogeneity of the precipitation extremes. (letters)
Lau, C.; Glümer, Charlotte; Spitters, Hilde
Background A policy game is a structured simulated role-play dealing with highly complex decision-making in real life network settings. Its impact on health enhancing physical activity (HEPA) policy making is unexplored. We aim to explore if an internationally developed and pilot tested policy game...... a policy game at local level, with 6 months intervals, including 18–19 policy makers in each game. Data was collected using a structured questionnaire one week after implementation of the games. Participants were asked if the game had changed their insight or attitude. Results: Response rate was 83%, 89......% and 89% in NL, DK and RO respectively. Across countries the majority of participants, 60%, enhanced their nderstanding of the local HEPA policy process, the roles in the organization network, and how stakeholders can collaborate as result of the game. Most participants perceived change in insight...
Connell, Ruth Sara
This study examines how frequently parental leave and other related childcare policies are available to academic librarians across the United States. It also looks at the relationships between policies offered and types of academic libraries that offer those policies. The author surveyed administrators at academic libraries serving baccalaureate,…
Sallé, Agnès; Demarsy, Delphine; Poirier, Anne Lise; Lelièvre, Bénédicte; Topart, Philippe; Guilloteau, Gérard; Bécouarn, Guillaume; Rohmer, Vincent
Although zinc deficiency is common after bariatric surgery, its incidence is underestimated. The objective was to monitor zinc and nutritional status before and 6, 12 and 24 months (M6, M12 and M24) after gastric bypass (Roux-en-Y gastric bypass), sleeve gastrectomy and biliopancreatic diversion with duodenal switch (DS) in patients receiving systematised nutritional care. Data for 324 morbidly obese patients (mean body mass index 46.2 ± 7.3 kg/m(2)) were reviewed retrospectively. The follow-up period was 6 months for 272 patients, 12 months for 175, and 24 months for 70. Anthropometric, dietary and serum albumin, prealbumin, zinc, iron and transferrin saturation measures were determined at each timepoint. Nine percent of patients had zinc deficiency pre-operatively. Zinc deficiency was present in 42.5% of the population at M12 and then remained stable. Zinc deficiency was significantly more frequent after DS, with a prevalence of 91.7% at M12. Between M0 and M6, variation in plasma prealbumin, surgery type and zinc supplementation explained 27.2% of the variance in plasma zinc concentration. Surgery type explained 22.1% of this variance between M0 and M24. Mean supplemental zinc intake was low (22 mg/day). The percentage of patients taking zinc supplementation at M6, M12 and M24 was 8.9%, 20.6% and 29%, respectively. Reduced protein intake, impaired zinc absorption and worsening compensatory mechanisms contribute to zinc deficiency. The mechanisms involved differ according to the type of surgery and time since surgery. Zinc supplementation is necessary early after bariatric surgery, but this requirement is often underestimated or is inadequate.
Singhi, Aatur D; Goyal, Alka; Davison, Jon M; Regueiro, Miguel D; Roche, Robyn L; Ranganathan, Sarangarajan
. Although anti-enterocyte antibodies were identified in the majority of the cases, their presence was variable and insensitive. In addition, pediatric autoimmune enteropathy was frequently encountered in the setting of immunodeficiency disorders.
Lucas, Timothy A; Johns, Garrett; Jiang, Wancen; Yang, Lucie
The recent increase in wildfire frequency in the Santa Monica Mountains (SMM) may substantially impact plant community structure. Species of Chaparral shrubs represent the dominant vegetation type in the SMM. These species can be divided into three life history types according to their response to wildfires. Nonsprouting species are completely killed by fire and reproduce by seeds that germinate in response to a fire cue, obligate sprouting species survive by resprouting from dormant buds in a root crown because their seeds are destroyed by fire, and facultative sprouting species recover after fire both by seeds and resprouts. Based on these assumptions, we developed a set of nonlinear difference equations to model each life history type. These models can be used to predict species survivorship under varying fire return intervals. For example, frequent fires can lead to localized extinction of nonsprouting species such as Ceanothus megacarpus while several facultative sprouting species such as Ceanothus spinosus and Malosma (Rhus) laurina will persist as documented by a longitudinal study in a biological preserve in the SMM. We estimated appropriate parameter values for several chaparral species using 25 years of data and explored parameter relationships that lead to equilibrium populations. We conclude by looking at the survival strategies of these three species of chaparral shrubs under varying fire return intervals and predict changes in plant community structure under fire intervals of short return. In particular, our model predicts that an average fire return interval of greater than 12 years is required for 50 % of the initial Ceanothus megacarpus population and 25 % of the initial Ceanothus spinosus population to survive. In contrast, we predict that the Malosma laurina population will have 90 % survivorship for an average fire return interval of at least 6 years.
Özbilgin, M; Ünek, T; Egeli, T; Ağalar, C; Özbilgin, Ş; Hancı, V; Ellidokuz, H; Astarcıoğlu, I
We investigated the liver transplantation literature since 1975 and found the most frequently cited 100 articles and assessed the distribution of authors and journals of these articles. Using the advanced mode of the Institute for Scientific Information (ISI) Web of Science (WOS) search engine, the words "SU = transplantation AND TI = liver OR SU = transplantation AND TS = liver" were used to scan articles and determine the most-cited 100 articles on July 18, 2016. From 1975 to date, it appears a total of 43,369 articles were published in the field of liver transplantation in the WOS. Although the most cited article had 677 citations, the least cited article had 180 citations. The mean citation number for the 100 articles was 252.31 ± 96.75. The mean annual citation number for the articles varied from 61.55 to 5 and the mean was 15.31 ± 8.63. The most cited article was by Feng et al "Characteristics Associated With Liver Graft Failure: The Concept of a Donor Risk Index" published in the American Journal of Transplantation (677 citations). Bibliometric analysis highlights the key topics and publications that have shaped the understanding and management of liver transplantation. According to our research, this is the first study to investigate articles with most citations in the field of liver transplantation. In our study the article with the most citations was cited 677 times, whereas the 100th article was cited 180 times with a mean citation number for the 100 articles of 252.31 ± 96.75. Copyright © 2017 Elsevier Inc. All rights reserved.
Sacchetti, Marta; Lambiase, Alessandro; Coassin, Marco; Bonini, Sergio; Bonini, Stefano
Overtreatment with topical ophthalmic preparations can lead to toxic corneal ulcer development. This study aimed to investigate the clinical and visual impact of toxic corneal ulcers and the management and risk factors for their development and outcomes. Clinical records of 226 consecutive patients with corneal ulcers referred to our tertiary care center were retrospectively evaluated. Frequency, clinical features, and management of toxic corneal ulcers are described. The relationship between clinical severity and outcomes (healing time, corneal transparency, and visual acuity) of toxic corneal ulcers and the number and classes of topical drugs, the number of daily instillations, and the duration of treatment were statistically evaluated. Toxic corneal ulcer was diagnosed in 9% (21/226) of all patients. After topical treatment discontinuation, the cornea spontaneously healed in all patients in 2 to 21 days. A longer healing time was related to a greater number of topical drugs used (p=0.029), a greater frequency of daily instillations (p=0.042), and a longer duration of treatment (p=0.048). The specific drugs used did not significantly influence healing time. After resolution, 16 out of 21 patients showed corneal scarring and impairment of visual function. The severity of corneal haze was related to the number of drugs used (p=0.023), to the frequency of daily instillations (p=0.031), and to the healing time (p=0.008). Toxic corneal ulcer is a frequent disease that can potentially lead to permanent visual impairment. A high-dose regimen is the major risk factor for corneal toxic ulcer development and poor visual outcomes.
Franklin, S.P.; Troyer, J.L.; TerWee, J.A.; Lyren, L.M.; Boyce, W.M.; Riley, S.P.D.; Roelke, M.E.; Crooks, K.R.; VandeWoude, S.
With the exception of human immunodeficiency virus (HIV), which emerged in humans after cross-species transmissions of simian immunodeficiency viruses from nonhuman primates, immunodeficiency viruses of the family Lentiviridae represent species-specific viruses that rarely cross species barriers to infect new hosts. Among the Felidae, numerous immunodeficiency-like lentiviruses have been documented, but only a few cross-species transmissions have been recorded, and these have not been perpetuated in the recipient species. Lentivirus seroprevalence was determined for 79 bobcats (Lynx rufus) and 31 pumas (Puma concolor) from well-defined populations in Southern California. Partial genomic sequences were subsequently obtained from 18 and 12 seropositive bobcats and pumas, respectively. Genotypes were analyzed for phylogenic relatedness and genotypic composition among the study set and archived feline lentivirus sequences. This investigation of feline immunodeficiency virus infection in bobcats and pumas of Southern California provides evidence that cross-species infection has occurred frequently among these animals. The data suggest that transmission has occurred in multiple locations and are most consistent with the spread of the virus from bobcats to pumas. Although the ultimate causes remain unknown, these transmission events may occur as a result of puma predation on bobcats, a situation similar to that which fostered transmission of HIV to humans, and likely represent the emergence of a lentivirus with relaxed barriers to cross-species transmission. This unusual observation provides a valuable opportunity to evaluate the ecological, behavioral, and molecular conditions that favor repeated transmissions and persistence of lentivirus between species. Copyright ?? 2007, American Society for Microbiology. All Rights Reserved.
Aford, Brandon; Lee, Shawna J
The 2010 repeal of Don't Ask, Don't Tell (DADT) is one example of how U.S. public policy has shifted toward greater inclusion of lesbian, gay, and bisexual (LGB) individuals. The repeal of DADT reversed the practice of discharging LGB service members on the basis of sexual identity. LGB service members may now serve their country without fear of direct repercussions stemming from sexual identity. Though it is a statutory step toward parity, DADT repeal does not address a number of cultural and institutional inequities that continue to hinder full inclusion of sexual minority service members. Notably, as discussed in this article, DADT largely ignores issues facing the transgender population. This study examines remaining inequities and their ramifications for lesbian, gay, bisexual, and transgender service members and their families. The article concludes with practice and policy recommendations for culturally competent social work practice with military service members across the sexual identity spectrum.
Conde, Ana R; Martins, Ana P; Brito, Miguel
Well-differentiated gastric carcinomas are considered to represent a distinct entity emerging via specific molecular changes different from those found in other gastric carcinoma types. The gene deleted in malignant brain tumours 1 (DMBT1) at 10q25.3-q26.1 codes for a protein presumably involved ...... preferentially take place in well-differentiated gastric carcinoma. However, an upregulation of DMBT1 expression is more frequently found across all gastric cancer types.......Well-differentiated gastric carcinomas are considered to represent a distinct entity emerging via specific molecular changes different from those found in other gastric carcinoma types. The gene deleted in malignant brain tumours 1 (DMBT1) at 10q25.3-q26.1 codes for a protein presumably involved...... in cell differentiation and protection and has been proposed as a candidate tumour suppressor for brain and epithelial cancer. One study reported a loss of DMBT1 expression in 12.5% (5/40) of gastric cancer samples. Here, we examined in more detail DMBT1 protein and mRNA expression in 78 primary gastric...
Harolds, Jay A
The type and caliber of the questions asked by a job hunter is one of the ways an interviewer will evaluate the candidate. Questions that show poor preparation should not be asked, such as failure to read what the employer sent to the job seeker or not doing elementary research on the practice, the organization, or the community. Asking about insignificant details also is not helpful. Not having any good questions to ask is a negative in an interview. This article discusses many possible important questions for the applicant to ask during an interview.
Tani, Pekka; Lindberg, Nina; Nieminen-von Wendt, Taina; von Wendt, Lennart; Alanko, Lauri; Appelberg, Björn; Porkka-Heiskanen, Tarja
Background Asperger syndrome (AS) is a neurodevelopmental disorder belonging to autism spectrum disorders with prevalence rate of 0,35% in school-age children. It has been most extensively studied in childhood while there is scarcity of reports concerning adulthood of AS subjects despite the lifelong nature of this syndrome. In children with Asperger syndrome the initiation and continuity of sleep is disturbed because of the neuropsychiatric deficits inherent of AS. It is probable that sleep difficulties are present in adulthood as well. Our hypothesis was that adults with AS suffer from difficulty in initiating and maintaining sleep and nonrestorative sleep (insomnia). Methods 20 AS without medication were compared with 10 healthy controls devoid of neuropsychiatric anamnesis. Clinical examination, blood test battery and head MRI excluded confounding somatic illnesses. Structured psychiatric interview for axis-I and axis-II disorders were given to both groups as well as Beck Depression Inventory and Wechsler adult intelligence scale, revised version. Sleep quality was assessed with sleep questionnaire, sleep diary during 6 consecutive days and description of possible sleep problems by the participants own words was requested. Results compared with controls and with normative values of good sleep, AS adults had frequent insomnia. In sleep questionnaire 90% (18/20), in sleep diary 75% (15/20) and in free description 85% (17/20) displayed insomnia. There was a substantial psychiatric comorbidity with only 4 AS subject devoid of other axis-I or axis-II disorders besides AS. Also these persons displayed insomnia. It can be noted that the distribution of psychiatric diagnoses in AS subjects was virtually similar to that found among patient with chronic insomnia. Conclusions the neuropsychiatric deficits inherent of AS predispose both to insomnia and to anxiety and mood disorders. Therefore a careful assessment of sleep quality should be an integral part of the treatment
Full Text Available Abstract Background Worldwide, acute leukemia is the most common type of childhood cancer. It is particularly common in the Hispanic populations residing in the United States, Costa Rica, and Mexico City. The objective of this study was to determine the incidence of acute leukemia in children who were diagnosed and treated in public hospitals in Mexico City. Methods Included in this study were those children, under 15 years of age and residents of Mexico City, who were diagnosed in 2006 and 2007 with leukemia, as determined by using the International Classification of Childhood Cancer. The average annual incidence rates (AAIR, and the standardized average annual incidence rates (SAAIR per million children were calculated. We calculated crude, age- and sex-specific incidence rates and adjusted for age by the direct method with the world population as standard. We determined if there were a correlation between the incidence of acute leukemias in the various boroughs of Mexico City and either the number of agricultural hectares, the average number of persons per household, or the municipal human development index for Mexico (used as a reference of socio-economic level. Results Although a total of 610 new cases of leukemia were registered during 2006-2007, only 228 fit the criteria for inclusion in this study. The overall SAAIR was 57.6 per million children (95% CI, 46.9-68.3; acute lymphoblastic leukemia (ALL was the most frequent type of leukemia, constituting 85.1% of the cases (SAAIR: 49.5 per million, followed by acute myeloblastic leukemia at 12.3% (SAAIR: 6.9 per million, and chronic myeloid leukemia at 1.7% (SAAIR: 0.9 per million. The 1-4 years age group had the highest SAAIR for ALL (77.7 per million. For cases of ALL, 73.2% had precursor B-cell immunophenotype (SAAIR: 35.8 per million and 12.4% had T-cell immunophenotype (SAAIR 6.3 per million. The peak ages for ALL were 2-6 years and 8-10 years. More than half the children (58.8% were
Aydin, B.; Angryk, R.; Filali Boubrahimi, S.; Hamdi, S. M.
Solar physics researchers entered the big data era with the launch of NASA's Solar Dynamics Observatory (SDO) mission, which captures approximately 60,000 high-resolution images every day and generates 0.55 petabytes of raster data each year. The big data trend in solar data is anticipated to be sustained by the ground-based DKIST telescope, which is expected to generate three to five petabytes of data each year. Many software modules continuously work on SDO's image data to detect spatial boundaries of solar events. Recently, a solar event tracking algorithm and interpolation methodologies have been proposed for creating large-scale solar event vector data sets in GSU's Data Mining Lab. The solar event tracking algorithm utilizes the spatial locations and corresponding image parameters for linking the polygon-based instances; therefore, creates spatiotemporal trajectory objects with extended geometric representations. Thus, we can access and make use of vector-based solar event metadata, which is in the form of continuously evolving region trajectories. Spatial and temporal patterns such as co-occurrences, sequences, periodicity and convergences frequently transpire among solar event instances. Here, we will concentrate on spatiotemporal co-occurrences and event sequences. Spatiotemporal co-occurrences are the spatial and temporal overlap among two or more solar event instances. On the other hand, spatiotemporal event sequences appear among the events that are temporally following each other and spatially in close-by locations. Our study includes approximately 120,000 trajectory-based instances of seven solar event types (Active Regions, Coronal Holes, Emerging Flux, Filaments, Flares, Sigmoids, and Sunspots) that occurred between January 2012 and December 2014. The tracked solar events are interpolated at each 10-minute interval. We will present the results of our spatiotemporal co-occurrence pattern mining and spatiotemporal event sequence mining algorithms
Pérez-Saldivar, María Luisa; Fajardo-Gutiérrez, Arturo; Bernáldez-Ríos, Roberto; Martínez-Avalos, Armando; Medina-Sanson, Aurora; Espinosa-Hernández, Laura; Flores-Chapa, José de Diego; Amador-Sánchez, Raquel; Peñaloza-González, José Gabriel; Alvarez-Rodríguez, Francisco Javier; Bolea-Murga, Victoria; Flores-Lujano, Janet; Rodríguez-Zepeda, María Del Carmen; Rivera-Luna, Roberto; Dorantes-Acosta, Elisa María; Jiménez-Hernández, Elva; Alvarado-Ibarra, Martha; Velázquez-Aviña, Martha Margarita; Torres-Nava, José Refugio; Duarte-Rodríguez, David Aldebarán; Paredes-Aguilera, Rogelio; Del Campo-Martínez, María de Los Ángeles; Cárdenas-Cardos, Rocío; Alamilla-Galicia, Paola Hillary; Bekker-Méndez, Vilma Carolina; Ortega-Alvarez, Manuel Carlos; Mejia-Arangure, Juan Manuel
Worldwide, acute leukemia is the most common type of childhood cancer. It is particularly common in the Hispanic populations residing in the United States, Costa Rica, and Mexico City. The objective of this study was to determine the incidence of acute leukemia in children who were diagnosed and treated in public hospitals in Mexico City. Included in this study were those children, under 15 years of age and residents of Mexico City, who were diagnosed in 2006 and 2007 with leukemia, as determined by using the International Classification of Childhood Cancer. The average annual incidence rates (AAIR), and the standardized average annual incidence rates (SAAIR) per million children were calculated. We calculated crude, age- and sex-specific incidence rates and adjusted for age by the direct method with the world population as standard. We determined if there were a correlation between the incidence of acute leukemias in the various boroughs of Mexico City and either the number of agricultural hectares, the average number of persons per household, or the municipal human development index for Mexico (used as a reference of socio-economic level). Although a total of 610 new cases of leukemia were registered during 2006-2007, only 228 fit the criteria for inclusion in this study. The overall SAAIR was 57.6 per million children (95% CI, 46.9-68.3); acute lymphoblastic leukemia (ALL) was the most frequent type of leukemia, constituting 85.1% of the cases (SAAIR: 49.5 per million), followed by acute myeloblastic leukemia at 12.3% (SAAIR: 6.9 per million), and chronic myeloid leukemia at 1.7% (SAAIR: 0.9 per million). The 1-4 years age group had the highest SAAIR for ALL (77.7 per million). For cases of ALL, 73.2% had precursor B-cell immunophenotype (SAAIR: 35.8 per million) and 12.4% had T-cell immunophenotype (SAAIR 6.3 per million). The peak ages for ALL were 2-6 years and 8-10 years. More than half the children (58.8%) were classified as high risk. There was a positive
von Wendt Lennart
Full Text Available Abstract Background Asperger syndrome (AS is a neurodevelopmental disorder belonging to autism spectrum disorders with prevalence rate of 0,35% in school-age children. It has been most extensively studied in childhood while there is scarcity of reports concerning adulthood of AS subjects despite the lifelong nature of this syndrome. In children with Asperger syndrome the initiation and continuity of sleep is disturbed because of the neuropsychiatric deficits inherent of AS. It is probable that sleep difficulties are present in adulthood as well. Our hypothesis was that adults with AS suffer from difficulty in initiating and maintaining sleep and nonrestorative sleep (insomnia. Methods 20 AS without medication were compared with 10 healthy controls devoid of neuropsychiatric anamnesis. Clinical examination, blood test battery and head MRI excluded confounding somatic illnesses. Structured psychiatric interview for axis-I and axis-II disorders were given to both groups as well as Beck Depression Inventory and Wechsler adult intelligence scale, revised version. Sleep quality was assessed with sleep questionnaire, sleep diary during 6 consecutive days and description of possible sleep problems by the participants own words was requested. Results compared with controls and with normative values of good sleep, AS adults had frequent insomnia. In sleep questionnaire 90% (18/20, in sleep diary 75% (15/20 and in free description 85% (17/20 displayed insomnia. There was a substantial psychiatric comorbidity with only 4 AS subject devoid of other axis-I or axis-II disorders besides AS. Also these persons displayed insomnia. It can be noted that the distribution of psychiatric diagnoses in AS subjects was virtually similar to that found among patient with chronic insomnia. Conclusions the neuropsychiatric deficits inherent of AS predispose both to insomnia and to anxiety and mood disorders. Therefore a careful assessment of sleep quality should be an
Jul 26, 2016 ... Ask-Upmark kidney with pelvi-ureteric junction obstruction. 191. Fig. 3. Specimen left kidney: gross examination shows left kidney smooth, grossly dilated with thinned out parenchyma. Fig. 4. (Hematoxylin and Eosin, 40×): histopathological examination of resected left kidney shows thyroidisation of tubules, ...
Chi, Nan; Yu, S.Y.; Xu, Lin
This paper presents an experimental assessment of the transmission performance and all-optical label swapping for an orthogonal amplitude-shift keying-frequency-shift keying (ASK/FSK) labeled signal. Transmission through different dispersion maps with various compensation schemes and fiber types ...... is investigated. All-optical label erasure, reinsertion, and multihop transmission are experimentally demonstrated....
Harrison, Ashley J.; Bradshaw, Laine P.; Naqvi, Nilofer C.; Paff, Madison L.; Campbell, Jonathan M.
ASD knowledge deficits contribute to disparities in the timing and quality of ASD services. To address the limitations with existing measures of ASD knowledge, we developed and examined the Autism Stigma and Knowledge Questionnaire (ASK-Q), which comprehensively assesses multiple subdomains of ASD knowledge while maintaining strong psychometric…
Aller, Wayne K.; And Others
In a study extending and refining Carol Chomsky's research, 48 Arabic speaking children aged six, eight, and ten were tested for their comprehension of imperatives using the complement-requiring verbs Ask, Tell, and Promise. Clear support for children's overgeneralization of the minimal distance principle was found only with Promise constructions.…
Hanousek, Jan; Podpiera, R.
Roč. 31, č. 2 (2003), s. 275-296 ISSN 0147-5967 R&D Projects: GA MŠk ME 595 Institutional research plan: CEZ:AV0Z7085904 Keywords : market microstructure * bid-ask spread * informed trading Subject RIV: AH - Economics Impact factor: 0.746, year: 2003
Barnes, William F.
Three recent untested theoretical models of the wage setting behavior of the unemployed jobseeker by Gronau, Mortensen, and McCall are compared. The investigation supports McCall's model which indicates downward flexibility in the minimum asking wage resulting from learning during search and unemployment. (Author/MW)
...In this document, the Wireless Telecommunications Bureau seeks comment on a December 3, 2010 petition for declaratory ruling (Petition) filed by CTIA-The Wireless Association (Petitioners). The Petitioners ask the Federal Communications Commission (Commission) to clarify ``the scope of Section 332(c)(3)(A)'s ban on state and local entry regulation.''
Teacher use questioning techniques to evaluate students' learning, check class work and homework, review and summarize lessons, and motivate students to pay attention, learn, develop thinking skills, and investigate independently. Teachers often overestimate the value of such questions. Asking thought-provoking questions and waiting for answers…
Informed consent procedures and requirements must be clearly established and communicated. The learning and proficiency practices should be restricted to the staff that can truly benefit from the experience. The practice of 'don't ask, don't tell' is not an option. South African Journal of Family Practice Vol. 50 (4) 2008: pp.
Rashmi Ranjan Paital
Full Text Available This paper empirically examines the relationship between stock return volatility, trading volume and bid-ask spread within the scope of mixture of distribution hypothesis (MDH and sequential information arrival hypothesis (SIAH in the Indian stock market using high frequency 5-minute data set over the period of 2 July 2012 to 31 December 2012. This is the first kind of study in India using bid-ask spread as an additional information variable along with trading volume to investigate the relationship with stock return volatility. Our empirical findings provide evidence of a positive contemporaneous relationship between return volatility and trading volume, and also between return volatility and bid-ask spread. Moreover, the results of Granger causality test show that the information content of trading volume and bid-ask spread are useful for predicting stock return volatility. Our results indicate that information arrival to investors tends to follow a sequential rather than a simultaneous process. This finding is consistent with the sequential information arrival hypothesis and contradicts the mixture of distribution hypothesis.
Cushing, Ellen; Meyer, Cassandra
States take a wide range of approaches to Student Learning Objectives (SLO) assessment selection. This "Ask the Team" brief helps states consider the trade-offs between approaches that offer more teacher choice and those that offer better comparability across SLOs. The brief identifies four common approaches to selecting SLO assessments:…
Camenga, Kristin A.
We discuss a mathematics capstone course designed to help students grow in mathematical independence. We describe how the course is structured to support this goal and the major assignments: a course wiki, a group expository project, and an individual problem to solve and extend. Students learn to ask and answer their own questions, helping them…
Gemellaro, Dorian Marrone
In this study, the researcher examined the strength and direction of relationships between NJ School Report Card Variables (NJ SRC) and 2008-2009 NJ ASK 5 Math and Language Arts Literacy (LAL) student test scores. Variables found to have an influence on standardized test scores in the extant literature were evaluated and reported. Analyses were…
Full Text Available Jakarta stock exchange (JSX and Surabaya Stock exchange (SSX were the organizers of capital market inIndonesia. Thus, to srengthen the capital market in Indonesia SSX merged into JSX on November 30th, 2007.New information coming into market would influence the trading activities, including trading volume activity(TVA, and bid-ask spread. While, merger also influenced the total issuer of listed companies in Indonesiastock exchange (IDX. This research included an event study with quantitative method about the analysis oftotal issuer differences, TVA and bid-ask spread before and after the merger announcement of SSX into JSX. Itused t-test method and autoregressive distribution lag test. The result of research analysis showed the difference,significance and insignificance. Based on t-test, the total issuer, TVA, and bid-ask spread were notsignificant before and after the merger announcement of SSX into JSX shown by the higher value of sig.2 tailedthan level of significance and value of standard deviation before the merger announcement of SSX into JSXfrom each variable. Based on autoregressive distribution lag test, it showed significant response by hightrading volume of TVA and bid-ask spread and also high volume of buy-offer investor did on several days ofwindows period before and after the merger announcement of SSX into JSX.
Kupper, Lisa, Ed.
This guide, available in both English and Spanish, answers questions often asked by parents about special education services. Questions and answers address the following topics: where to begin if a parent believes a child needs special education services, services available to very young children, the evaluation process, the Individualized…
... problem from happening again. (b) Give us data from production-line testing that shows the remedied engine... (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM NEW, SMALL NONROAD SPARK-IGNITION ENGINES AND EQUIPMENT Production-line Testing § 1054.335 How do I ask EPA to reinstate my suspended certificate? (a...
... (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM NEW, LARGE NONROAD SPARK-IGNITION ENGINES Testing Production-line Engines § 1048.335 How do I ask EPA to reinstate my suspended certificate? (a... problem from happening again. (b) Give us data from production-line testing that shows the remedied engine...
... (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM SPARK-IGNITION PROPULSION MARINE ENGINES AND VESSELS Testing Production-line Engines § 1045.335 How do I ask EPA to reinstate my suspended certificate... problem from happening again. (b) Give us data from production-line testing that shows the remedied engine...
Everett, Gregory E.; Harsy, Jennifer D.; Hupp, Stephen D. A.; Jewell, Jeremy D.
The current study evaluated the effects of the Look-Ask-Pick (LAP) mnemonic on the addition and subtraction of fraction skills of 3 general education sixth graders. Following identification of fraction skill deficits, participants were taught to add and subtract fractions with like denominators, unlike denominators where one divides evenly into…
Okay, Sezer; Ünsaldı, Eser; Taşkın, Bilgin; Liras, Paloma; Piret, Jacqueline
In this study, the effect of homologous multiple copies of the ask gene, which encodes aspartokinase catalyzing the first step of the aspartate pathway, on cephamycin C biosynthesis in S. clavuligerus NRRL 3585 and its hom mutant was investigated. The intracellular pool levels of aspartate pathway amino acids accorded well with the Ask activity levels in TB3585 and AK39. When compared with the control strain carrying vector alone without any gene insert, amplification of the ask gene in the wild strain resulted in a maximum of 3.1- and 3.3-fold increase in specific, 1.7- and 1.9-fold increase in volumetric cephamycin C production when grown in trypticase soy broth (TSB) and a modified chemically defined medium (mCDM), respectively. However, expression of multicopy ask gene in a hom-deleted background significantly decreased cephamycin C yields when the cells were grown in either TSB or mCDM, most probably due to physiological disturbance resulting from enzyme overexpression and high copy number plasmid burden in an auxotrophic host, respectively. PMID:21326925
This policy reader comprises: Correspondence; Memorandum of Understanding between the US Department of Transportation and the US Department of Energy for the Transportation of Radioactive Materials under the Nuclear Waste Policy Act; Internal Guidelines for Interactions with Communities and Local Governments; Statement by Ben C. Rusche before the Committee on Interior and Insular Affairs, Subcommittee on Energy and the Environment, US House of Representatives, September 13, 1985; Speech presented by Ben C. Rusche before the ANS/CNS/AESJ/ENS Topical Meeting, Pasco, Washington, September 24, 1985 - ''Status of the United States' High-Level Nuclear Waste Disposal Program''; and ''DOE Seeks Comments on Nuclear Transportation Planning,'' DOE News, September 30, 1985
Participants in the Seminar on Population Policies for Top-level Policy Makers and Program Managers, meeting in Thailand during January 1987, examined the challenges now facing them regarding the implementation of fertility regulation programs in their respective countries -- Bangladesh, China, India, Indonesia, Malaysia, Nepal, Pakistan, the Philippines, the Republic of Korea, and Thailand. This Seminar was organized to coincide with the completion of an Economic and Social Commission for Asia and the Pacific (ESCAP) study investigating the impact and efficiency of family planning programs in the region. Country studies were reviewed at the Seminar along with policy issues about the status of women, incentive and disincentive programs, and socioeconomic factors affecting fertility. In Bangladesh the government recognizes population growth as its top priority problem related to the socioeconomic development of the country and is working to promote a reorientation strategy from the previous clinic-oriented to a multidimensional family welfare program. China's family planning program seeks to postpone marraige, space the births of children between 3-5 years, and promote the 1-child family. Its goal is to reduce the rate of natural increase from 12/1000 in 1978 to 5/1000 by 1985 and 0 by 2000. India's 7th Five-Year-Plan (1986-90) calls for establishing a 2-child family norm by 2000. In Indonesia the government's population policy includes reducing the rate of population growth, achieving a redistribution of the population, adjusting economic factors, and creating prosperous families. The government of Indonesia reversed its policy to reduce the population growth rate in 1984 and announced its goal of achieving a population of 70 million by 2100 in order to support mass consumption industries. It has created an income tax deduction system favoring large families and maternity benefits for women who have up to 5 children as incentives. Nepal's official policy is to
Lauridsen, Karen M.
Like any other text, instructive texts function within a given cultural and situational setting and may only be available in one language. However, the end users may not be familiar with that language and therefore unable to read and understand the instructions. This article therefore argues...... that instructive texts should always be available in a language that is understood by the end users, and that a corporate communication policy which includes a language policy should ensure that this is in fact the case for all instructive texts....
Kritz, M M
Kritz reviews national concepts and policies of migration. She examines how nation-states approach migration and how they define who is a migrant. Policies for permanent, temporary, and illegal migrants are examined for selected countries. While the traditional permanent immigration countries--Australia, Canada, New Zealand, and the US--continue to admit large numbers of permanent migrants, they are also admitting growing numbers of temporary migrants. Other countries, in Europe and the developing world, have different migration histories and use other approaches to admit foreigners--migrants are generally admitted on a temporary basis for work or other purposes. Growing numbers of these temporary migrants, however, do become long-term or permanent settlers, and the distinction between permanent and temporary migration policies becomes a short-term legal one rather than a long-term sociological one. Governments have been seeking those policy instruments that would allow them to improve control over who enters and settles in their territories, and temporary migration policies are the measures to which they are turning. While increasing restriction characterizes the policy stance of most countries toward international migration, this does not necessarily mean that the number of migrants entering is declining. Kritz argues that the concepts employed by countries in their immigration policies frequently do not correspond to the reality, making it necessary to examine the actual context.
Kinnersley, Paul; Edwards, Adrian; Hood, Kerry; Ryan, Rebecca; Prout, Hayley; Cadbury, Naomi; MacBeth, Fergus; Butow, Phyllis; Butler, Christopher
To assess the effects on patients, clinicians, and the healthcare system of interventions before consultations to help patients or their representatives gather information in consultations by question asking. Systematic review with meta-analysis. Electronic literature searches of seven databases and hand searching of one journal and bibliographies of relevant articles. Review methods Inclusion criteria included randomised controlled trials. Primary outcomes were question asking; patients' anxiety, knowledge, and satisfaction; and length of consultation. 33 randomised trials of variable quality involving 8244 patients were identified. A few studies showed positive effects. Meta-analyses showed small and statistically significantly increases in question asking (standardised mean difference 0.27, 95% confidence interval 0.19 to 0.36) and patients' satisfaction (0.09, 0.03 to 0.16). Non-statistically significant changes occurred in patients' anxiety before consultations (weighted mean difference -1.56, -7.10 to 3.97), patients' anxiety after consultations (standardised mean difference -0.08, -0.22 to 0.06), patients' knowledge (-0.34, -0.94 to 0.25), and length of consultation (0.10, -0.05 to 0.25). Interventions comprising written materials had similar effects on question asking, consultation length, and patients' satisfaction as those comprising the coaching of patients. Interventions with additional training of clinicians had little further effect than those targeted at patients alone for patients' satisfaction and consultation length. Interventions for patients before consultations produce small benefits for patients. This may be because patients and clinicians have established behaviours in consultations that are difficult to change. Alternatively small increases in question asking may not be sufficient to make notable changes to other outcomes.
Yerke, Adam F; Mitchell, Valory
The repeal of Don't Ask, Don't Tell offered legal equality to sexual minorities in the military. However, this big step forward had no impact on the policy of exclusion and rejection and the fear and secrecy that resulted for transgender people (whether lesbian, gay, bisexual, or heterosexual). In this article, we argue that transgender citizens should have equal opportunity to honorably serve their country, and to be treated with respect and sensitivity as they do so. Many transgender persons may be drawn to military service and its ethos of masculine values. However, they are currently not permitted entry, and, if they are to enter, must remain hidden or face dismissal, leaving them vulnerable to harassment. While they report both positive and negative experiences during their service, research documents discrimination in veterans' healthcare as well as mental health risks resulting from fear and harassment. In contrast to the United States, 11 countries include transgender people in their militaries. Drawing in part from their examples, we end with recommendations for change in the direction of respect and equality of opportunity.
Huey, Laura; Broll, Ryan; Hryniewicz, Danielle; Fthenos, Georgios
As "access brokers" to resources for their clients, homeless shelter workers are often in a position to aid victimized homeless women in securing medical and psychological services post-victimization. Given high rates of victimization within this population, we would expect that a routine part of a shelter's case management process would involve queries regarding victimization. Through in-depth qualitative interviews with 42 victimized homeless women in Chicago and Detroit, we sought to discover the extent to which such queries were pursued by staff at their current shelter. What we found is that women are seldom asked to provide a complete history that includes experiences of violent victimization and its effects. From these results, we make several recommendations aimed at improving homeless victims' access to services.
The main question asked in this thesis is how market-based governance structures influence the resource utilisation in public sector. The four essays are predominately occupied with policy issues. For instance, all essays are inspired by public sector reforms implemented across OECD member states during the last ten to fifteen years. Three out of four essays are applied econometric work concerned with analysing and describing effects of reforms made in the health care and social care sectors....
Zhuang, Juzhong; Kanbur, Ravi; Rhee, Changyong
This paper looks at the recent trends of rising inequality in developing Asia, asks why inequality matters, examines the driving forces of rising inequality, and proposes policy options for tackling high and rising inequality. Technological change, globalization, and market-oriented reform have driven Asiaâ€™s rapid growth, but have also had significant distributional consequences. These factors have favored owners of capital over labor, skilled over unskilled workers, and urban and coastal a...
This tutorial is aimed at those who are new to the area of repositories and who want to learn more about key advocacy and policy issues. The tutorial will include information and advice on putting together an institutional advocacy campaign and developing policies for your repository. There will be opportunities for participants to share experiences and to ask questions. The tutorial will include a practical exercise in developing an advocacy presentation. Participants with experience of advocacy are welcome to attend the session to share their experiences, but should bear in mind that it is aimed primarily at those looking for help and advice in advocacy matters.
Netto, Carlos Pinto Coelho Amaral
Mestrado em Economia da Empresa e da Concorrência / JEL Codes: Q42; N74 Policies chosen to promote renewables can vary significantly and determine different levels of deployment, efficiency and technological innovation. Instruments in this sector have been mostly directed towards electricity generation and are usually divided into two main types: feed-in tariffs and quota obligations. The former is more frequent in the European Union and is associated with higher levels of deployment, as w...
Fu, Meili; Wan, Fuqiang; Li, Zhengling; Zhang, Fenghua
The aim of the present study is to investigate the potential anti-hepatocellular carcinoma (HCC) cell activity by 4SC-202, a novel class I HDAC inhibitor (HDACi). The associated signaling mechanisms were also analyzed. We showed that 4SC-202 treatment induced potent cytotoxic and proliferation–inhibitory activities against established HCC cell lines (HepG2, HepB3, SMMC-7721) and patient-derived primary HCC cells. Further, adding 4SC-202 in HCC cells activated mitochondrial apoptosis pathway, which was evidenced by mitochondrial permeability transition pore (mPTP) opening, cytochrome C cytosol release and caspase-3/-9 activation. Inhibition of this apoptosis pathway, by caspase-3/-9 inhibitors, mPTP blockers, or by shRNA-mediated knockdown of cyclophilin-D (Cyp-D, a key component of mPTP), significantly attenuated 4SC-202-induced HCC cell death and apoptosis. Reversely, over-expression of Cyp-D enhanced 4SC-202's sensitivity in HCC cells. Further studies showed that 4SC-202 induced apoptosis signal-regulating kinase 1 (ASK1) activation, causing it translocation to mitochondria and physical association with Cyp-D. This mitochondrial ASK1-Cyp-D complexation appeared required for mediating 4SC-202-induced apoptosis activation. ASK1 stable knockdown by targeted-shRNAs largely inhibited 4SC-202-induced mPTP opening, cytochrome C release, and following HCC cell apoptotic death. Together, we suggest that 4SC-202 activates ASK1-dependent mitochondrial apoptosis pathway to potently inhibit human HCC cells. - Highlights: • 4SC-202 exerts potent anti-proliferative and cytotoxic activity against established/primary HCC cells. • SC-202-induced anti-HCC cell activity relies on caspase-dependent apoptosis activation. • 4SC-202 activates Cyp-D-dependent mitochondrial apoptosis pathway in HCC cells. • 4SC-202 activates ASK1 in HCC cells, causing it translocation to mitochondria. • Mitochondrial ASK1-Cyp-D complexation mediates 4SC-202's activity in HCC cells.
Fu, Meili, E-mail: firstname.lastname@example.org [Department of Infectious Disease, Linyi People' s Hospital, Linyi 276000 (China); Wan, Fuqiang [Department of Head and Neck Surgery, Linyi Tumor Hospital, Linyi 276000 (China); Li, Zhengling [Department of Nursing, Tengzhou Central People' s Hospital, Tengzhou 277500 (China); Zhang, Fenghua [Department of Operating Room, Linyi People' s Hospital, Linyi 276000 (China)
The aim of the present study is to investigate the potential anti-hepatocellular carcinoma (HCC) cell activity by 4SC-202, a novel class I HDAC inhibitor (HDACi). The associated signaling mechanisms were also analyzed. We showed that 4SC-202 treatment induced potent cytotoxic and proliferation–inhibitory activities against established HCC cell lines (HepG2, HepB3, SMMC-7721) and patient-derived primary HCC cells. Further, adding 4SC-202 in HCC cells activated mitochondrial apoptosis pathway, which was evidenced by mitochondrial permeability transition pore (mPTP) opening, cytochrome C cytosol release and caspase-3/-9 activation. Inhibition of this apoptosis pathway, by caspase-3/-9 inhibitors, mPTP blockers, or by shRNA-mediated knockdown of cyclophilin-D (Cyp-D, a key component of mPTP), significantly attenuated 4SC-202-induced HCC cell death and apoptosis. Reversely, over-expression of Cyp-D enhanced 4SC-202's sensitivity in HCC cells. Further studies showed that 4SC-202 induced apoptosis signal-regulating kinase 1 (ASK1) activation, causing it translocation to mitochondria and physical association with Cyp-D. This mitochondrial ASK1-Cyp-D complexation appeared required for mediating 4SC-202-induced apoptosis activation. ASK1 stable knockdown by targeted-shRNAs largely inhibited 4SC-202-induced mPTP opening, cytochrome C release, and following HCC cell apoptotic death. Together, we suggest that 4SC-202 activates ASK1-dependent mitochondrial apoptosis pathway to potently inhibit human HCC cells. - Highlights: • 4SC-202 exerts potent anti-proliferative and cytotoxic activity against established/primary HCC cells. • SC-202-induced anti-HCC cell activity relies on caspase-dependent apoptosis activation. • 4SC-202 activates Cyp-D-dependent mitochondrial apoptosis pathway in HCC cells. • 4SC-202 activates ASK1 in HCC cells, causing it translocation to mitochondria. • Mitochondrial ASK1-Cyp-D complexation mediates 4SC-202's activity in HCC cells.
School governing bodies in England have considerable powers and responsibilities with regard to the education of pupils. This paper draws on an analysis of policy and on qualitative research in the governing bodies of four maintained schools. It explores two policy technologies through which education and the work of school governing bodies are…
Te One, Sarah; Blaikie, Rebecca; Egan-Bitran, Michelle; Henley, Zoey
Recent social policy discourses in Aotearoa New Zealand focus on vulnerable children's well-being and the detrimental, long-term and costly impacts of child poverty. The discourse pervading much of the policy labels children and young people as "vulnerable" or "at risk" or "in crisis", a view, which we argue, is both…
Full Text Available This paper tests the validity of the Corwin-Schultz bid-ask spread estimator in the Brazilian stock market. The Corwin-Schultz estimator arises as an easy way to compute asymmetric information throughout daily high and low stock prices for estimating overnight and non-negative adjusted spreads. The sample consisted of Ibovespa firms from 1986 to 2014 and was analysed with time series econometrics. The findings show that the measures of spread have stationarity properties, allowing for forecasting in a period of lagged variables, besides having the property of time-varying cointegration with market-to-book ratio, debt on equity, size and return and also presenting sensibility to different periods, industries and listing segments. Thus, the Corwin-Schultz bid-ask spread estimator seems to be a valid and reliable measure for forecasting aggregate-data variables through the weighted average of firm-level variables.
Morton, B; Richardson, A; Duncan, S
The National Institute for Clinical Excellence in the UK has issued guidelines stating all individuals with epilepsy be given information about sudden unexpected death in epilepsy (SUDEP). We conducted a survey of current practice among UK neurologists, using a questionnaire sent to all practising neurologists in the UK listed on the Association of British Neurologists database, asking under what circumstances they told patients about SUDEP. Of the validated respondents, 5% discussed SUDEP with all patients, 26% with a majority, 61% with a few, and 7.5% with none. The commonest reasons for SUDEP to be discussed were the patient asking about it and the neurologist counselling people with known risk factors for SUDEP. The variation we found, although not necessarily in tune with the guidelines, reflects the variation in patients' need for knowledge about their condition.
Zhou, Qirui; Ma, Jun; Lu, Yang; Huang, Lingchen; Chen, Biao
A novel evolution scheme from legacy TDM-PON to the next generation WDM-PON with DPSK/ASK orthogonal modulation is proposed. The new WDM-PON is added into the existing PON infrastructure and coexisting with the current TDM-PON. To eliminate any change requirement for the existing TDM-PON, DPSK is applied for WDM-PON downstream. Meanwhile, upstream remodualtion is applied to achieve colorless ONU in WDM-PON. The application of DPSK/ASK reduces both crosstalk from coexisting and remodulation. The experiment results show the crosstalk is very little. Good performance is achieved for both unchanged coexisting TDM-PON and WDM-PON upstream signals in our proposed scheme.
There is a clear association between antibiotic use and resistance both on individual and population levels. In the European Union, countries with large antibiotic consumption have higher resistance rates. Antibiotic resistance leads to failed treatments, prolonged hospitalisations, increased costs and deaths. With few new antibiotics in the Research & Development pipeline, prudent antibiotic use is the only option to delay the development of resistance. Antibiotic policy consists of prescrib...
Gong, Y.; Janssen, M.
Adapting to and complying with frequently changing policy against low costs requires flexible business processes. Yet, existing systems are unrelated, consist of operating silos, involve many human translation tasks and policies are hardcoded in business processes. From a technology perspective,
Gooyert, V. de; Rouwette, E.A.J.A.; Kranenburg, H.L. van; Freeman, R.E.; Breen, H.J. van
Various countries seek to establish an energy transition, a structural change towards a more sustainable energy system. Countries implement a combination of energy policies aimed at establishing an energy transition, but these policies frequently result in unintended negative consequences. This
New question and answer websites Ask.fm and Formspring have brought highly specific and personal abuse to a new level amongst young people by providing easy anonymity to users within a circle of offline friendship groups culled from Facebook. Relatively unknown due to their unattractiveness to adults, these sites are growing rapidly and have already been associated with at least eight suicides amongst teenagers. \\ud \\ud Media educators at school level encouraging self-awareness of social medi...
Waldorff, Frans Boch; Rishoj, Susanne; Waldemar, Gunhild
OBJECTIVES: To investigate the prevalence and potential clinical implications of self-reported memory impairment among elderly patients in general practice. METHODS: This was a cross-sectional study in 17 general practices serving 40,865 patients, of whom 2934 were 65 years of age or older. Outco...... will not present with these symptoms. It may be useful for general practitioners to ask about memory problems in order to identify potentially frail patients. Prospective trials are warranted....
APPL is a research-based organization that serves NASA program and project managers, as well as project teams, at every level of development. In 1997, APPL was created from an earlier program to underscore the importance that NASA places on project management and project teams through a wide variety of products and services, including knowledge sharing, classroom and online courses, career development guidance, performance support, university partnerships, and advanced technology tools. ASK Magazine grew out of APPL's Knowledge Sharing Initiative. The stories that appear in ASK are written by the 'best of the best' project managers, primarily from NASA, but also from other government agencies and industry. Contributors to this issue include: Teresa Bailey, a librarian at the Jet Propulsion Laboratory, Roy Malone, Deputy Director in the Safety and Mission Assurance (S&MA) Office at the NASA Marshall Space Flight Center (MSFC), W. Scott Cameron, Capital Systems Manager for the Food and Beverage Global Business Unit of Procter and Gamble, Ray Morgan, recent retiree as Vice President of AeroVironment, Inc., Marty Davis, Program Manager of the Geostationary Operational Environmental Satellite (GOES) at the NASA Goddard Space Flight Center (GSFC) in Greenbelt, Maryland, Todd Post, editor of ASK Magazine, and works for EduTech Ltd. in Silver Spring, Maryland, Dr. Owen Gadeken, professor of Engineering Management at the Defense Acquisition University, Ken Schwer, currently the Project Manager of Solar Dynamics Observatory, Dr. Edward Hoffmwan, Director of the NASA Academy of Program and Project Leadership, Frank Snow, a member of the NASA Explorer Program at Goddard Space Flight Center since 1992, Dr. Alexander Laufer, Editor-in-Chief of ASK Magazine and a member of the Advisory Board of the NASA Academy of Program and Project Leadership, Judy Stokley, presently Air Force Program Executive Officer for Weapons in Washington, D.C. and Terry Little, Director of the Kinetic
Schmidt, Sarah J.; Douglas, Stephanie; Gosnell, Natalie M.; Muirhead, Philip S.; Booth, Rachel S.; Davenport, James R. A.; Mace, Gregory N.
We examine the gender balance of the 18th and 19th meetings of the Cambridge Workshop on Cool Stellar Systems and the Sun (CS18 and CS19). The percent of female attendees at both meetings (31% at CS18 and 37% at CS19) was higher than the percent of women in the American Astronomical Society (25%) and the International Astronomical Union (18%). The representation of women in Cool Stars as SOC members, invited speakers, and contributed speakers was similar to or exceeded the percent of women attending the meetings. We requested that conference attendees assist in a project to collect data on the gender of astronomers asking questions after talks. Using this data, we found that men were over-represented (and women were under-represented) in the question sessions after each talk. Men asked 79% of the questions at CS18 and 75% of the questions at CS19, but were 69% and 63% of the attendees respectively. Contrary to findings from previous conferences, we did not find that the gender balance of questions was strongly affected by the session chair gender, the speaker gender, or the length of the question period. We also found that female and male speakers were asked a comparable number of questions after each talk. The contrast of these results from previous incarnations of the gender questions survey indicate that more data would be useful in understanding the factors that contribute to the gender balance of question askers. We include a preliminary set of recommendations based on this and other work on related topics, but also advocate for additional research on the demographics of conference participants. Additional data on the intersection of gender with race, seniority, sexual orientation, ability and other marginalized identities is necessary to fully address the role of gender in asking questions at conferences.
This project attempts to provide one cognitive, that is, schematic, network of all occurrences of the Qurʔānic saʔala "ask." The theoretical framework to argue for the proposed network is dual: to argue for a number of pragmatic functions that seem to underlie the choice of saʔala; and to make a strong case that these ...
Kylarová, Salome; Košek, Dalibor; Petrvalská, Olivia; Pšenáková, Katarína; Man, Petr; Večeř, J.; Herman, P.; Obšilová, Veronika; Obšil, Tomáš
Roč. 283, č. 20 (2016), s. 3821-3838 ISSN 1742-464X R&D Projects: GA ČR(CZ) GA14-10061S; GA MŠk(CZ) ED1.1.00/02.0109 Institutional support: RVO:67985823 ; RVO:61388971 Keywords : ASK 1 * cysteine * disulfide bond * mass spectrometry * TRX Subject RIV: CE - Biochemistry; EE - Microbiology, Virology (MBU-M) Impact factor: 3.902, year: 2016
Dungey, Azie Mira; Tyson, Amy M
In this interview, Azie Mira Dungey (creator of the web series, "Ask a Slave") and Amy M. Tyson (Associate Professor of History at DePaul University and author of The Wages of History: Emotional Labor on Public History's Front Lines) discuss Dungey's web series, as well as her experiences as a living history interpreter at both the Smithsonian Museum of American History and at Mount Vernon.
Lehr, William H.; Pupillo, Lorenzo Maria
The Internet is now widely regarded as essential infrastructure for our global economy and society. It is in our homes and businesses. We use it to communicate and socialize, for research, and as a platform for E-commerce. In the late 1990s, much was predicted about what the Internet has become at present; but now, we have actual experience living with the Internet as a critical component of our everyday lives. Although the Internet has already had profound effects, there is much we have yet to realize. The present volume represents a third installment in a collaborative effort to highlight the all-encompassing, multidisciplinary implications of the Internet for public policy. The first installment was conceived in 1998, when we initiated plans to organize an international conference among academic, industry, and government officials to discuss the growing policy agenda posed by the Internet. The conference was hosted by the European Commission in Brussels in 1999 and brought together a diverse mix of perspectives on what the pressing policy issues would be confronting the Internet. All of the concerns identified remain with us today, including how to address the Digital Divide, how to modify intellectual property laws to accommodate the new realities of the Internet, what to do about Internet governance and name-space management, and how to evolve broadcast and telecommunications regulatory frameworks for a converged world.
Full Text Available Background. Few studies have explored how providers communicate about control medications during pediatric asthma visits. Objectives. The purpose of this study was to: (a describe the extent to which providers discuss, educate, and ask children and their caregivers questions about control medications and (b examine how child, caregiver, and provider characteristics are associated with provider communication about control medications during pediatric asthma visits. Methods. Children ages 8 through 16 with mild, moderate, or severe persistent asthma and their caregivers were recruited at five pediatric practices in nonurban areas of North Carolina. After audio-tape recording medical visits, caregivers completed questionnaires and children were interviewed. Generalized estimating equations were used to analyze the data. Results. Providers educated families about control medications during 61% of the visits, and they asked questions about control medications during 67% of visits. Providers were significantly more likely to discuss control medications if a child was taking a control medication, if the child had moderate to severe persistent asthma, and if the child was present for an asthma-related visit. Conclusion. Providers need to educate and ask more questions of families about side effects and how well control medications are working.
Gardiner, Paula; Sadikova, Ekaterina; Filippelli, Amanda C; White, Laura F; Jack, Brian W
To explore inpatient reconciliation of dietary supplement (DS) use and determine characteristics associated with DS documentation. We analyzed DS use among 558 inpatients recruited from the Re-Engineered Discharge clinical trial to identify: (1) if patients self-reported DS and (2) if DS use was documented at admission. We examined socio-demographics for association with documentation using chi squares and t-tests. Logistic regression was performed to assess adjusted associations with DS documentation. Sixty percent reported DS use (n=333). Among users, 36% had admission DS documentation, 20% were asked about use at admission, 18% reported disclosing use to a provider, and 48% reported they would continue to use DS. Overall, 6% of participants were asked, disclosed, and had documentation of DS. Logistic regression revealed increased age associated with lower odds of DS documentation. Identifying as Hispanic or African American reduces DS documentation odds compared to those identifying as white. There is lack of consistent DS medical reconciliation in the inpatient setting. While more than half of patients used DS prior to hospitalization, most were not asked about use on admission. This study adds to literature on medical reconciliation which requires that providers inquire and document patient DS use. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.
Gardiner, Paula; Sadikova, Ekaterina; Filippelli, Amanda C.; White, Laura F.; Jack, Brian W.
Objective To explore inpatient reconciliation of dietary supplement (DS) use and determine characteristics associated with DS documentation. Methods We analyzed DS use among 558 inpatients recruited from the Re-Engineered Discharge clinical trial to identify: 1) if patients self-reported DS and 2) if DS use was documented at admission. We examined socio-demographics for association with documentation using chi squares and t-tests. Logistic regression was performed to assess adjusted associations with DS documentation. Results Sixty percent reported DS use (n=333). Among users, 36% had admission DS documentation, 20% were asked about use at admission, 18% reported disclosing use to a provider, and 48% reported they would continue to use DS. Overall, 6% of participants were asked, disclosed, and had documentation of DS. Logistic regression revealed increased age associated with lower odds of DS documentation. Identifying as Hispanic or African American reduces DS documentation odds compared to those identifying as white. Conclusions There is lack of consistent DS medical reconciliation in the inpatient setting. While more than half of patients used DS prior to hospitalization, most were not asked about use on admission. Practice Implications This study adds to literature on medical reconciliation which requires that providers inquire and document patient DS use. PMID:25636694
Hodgson, Kate; Darling, Marcia; Freeman, Douglas; Monavvari, Alan
This research explored whether asking patients about their pets would enable better environmental/social history taking, and improve patient communication/care. Primary health care providers (PHPs) were surveyed about prevalence of patients living with pets, the health impact of pets, and influences on patient communication. Following an educational intervention, they committed to asking patients about their pets. A follow-up survey was conducted electronically. PHPs were recruited at a continuing medical education (CME) conference and at CME workshops. All 225 participants were PHPs. At the conference, participants were educated one-on-one about the clinical relevance of pets in the family. CME sessions were large or small group teaching. Baseline and final surveys measured awareness of pets in patients' families, assessment of determinants of health, impact on rapport with patients, and patient care. A sign test assessed difference in scores using repeated-measures analysis. Binomial outcomes were assessed using Fisher's exact test. Comments were themed. Ninety-four PHPs (42%) completed the study. Pet-related discussions opened communication with patients. Two-thirds of participants identified positive effects on practice and on relationships with patients. PHPs were able to leverage the health benefits of pets (zooeyia) and mitigate zoonotic risk. Asking patients about pets in the family reveals clinically relevant information, improves communication, and strengthens the therapeutic alliance.
Maynard, Douglas W; Hollander, Matthew M
This paper is in the vein of applied conversation analysis, dealing with a problem of declining participation rates for survey interviews. When calling a household to request participation in a survey, interviewers may ask for a pre-selected "sample person." We first explore how interviewers design this request in a more or less presumptive way, depending on how and when they identify themselves. Secondly, we analyze different linguistic structures that embody degrees of entitlement. Thirdly, we examine greeting items for their degree of ceremoniousness and in terms of what work they do when not part of an explicit greeting sequence. We examine other features of asking to speak to another as well, including "please" and references to the sample person. Our strategy for analyzing survey interview data is to explore the design of "switchboard" requests in ordinary telephone calls. We relate our analysis to previous research that addresses whether the detailed practices for asking to speak to another matter for obtaining consent to do an interview. We draw implications for obtaining participation in the survey interview and other kinds of phone call solicitations. Data in American English.
Farooq Alam Khan
Full Text Available Abstract Much literature on electronic government services research could be found on adoptability issues from government and service providers point of view. Many studies have looked into adoptability factors from user perspectives and majority captured adoptability perspectives of frequent Internet users the ones who use Internet applications for more than 10 hours a week. On the contrary the perspectives of majority of Pakistani users which use Internet applications for less than 10 hours per week are never inquired. This paper tries to fill this gap by looking into electronic government adoptability perspectives and expectations of such Internet users of Pakistan which are much greater in numbers than others. An amended UTAUT model with all its moderators is used in this study and the results demonstrate that performance level ease of effort and social influence strongly effect behavioral intention of users in using electronic government services in Pakistan. The individuals behavioral intention along with presence of appropriate facilitating conditions triggers use behavior of users. The results show that only gender moderates majority of UTAUT relationships and accordingly a modified UTAUT model is presented. The paper provides certain insights for people making policies and academicians for performing further research while it stresses for service proliferation with special attention towards female population.
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Giddens, Jennifer M.
Objective: The author of the widely used suicidality scale, the Columbia–Suicide Severity Rating Scale, has repeatedly made the claim that asking the question, “Do you think you would be better off dead?” in suicidality assessment delivers false positive results. This case study investigates the value of this question as an immediate antecedent to impulsive suicidality and as a correlate of functional impairment. Method: One subject with daily suicidality and frequent impulsive suicidality rated five passive suicidal ideation phenomena and impulsive suicidality daily on a 0 to 4 Likert scale and rated weekly functional impairment scores for 13 weeks on a 0 to 10 Discan metric. Results: Each of the five passive suicidal ideation phenomena studied frequently occurred at a different severity level, and the five phenomena did not move in synchrony. Most passive suicidal ideation phenomena were very low on dates of impulsive suicidality. Thoughts of being better off dead were a frequent antecedent to impulsive suicidality and were related to an increase in functional impairment. Conclusion: The relationship to both functional impairment and impulsive suicidality suggest that it is potentially dangerous to ignore thoughts of being better off dead in suicidality assessment. PMID:25520897
Schmidt, Robert L; Chute, Deborah J; Colbert-Getz, Jorie M; Firpo-Betancourt, Adolfo; James, Daniel S; Karp, Julie K; Miller, Douglas C; Milner, Danny A; Smock, Kristi J; Sutton, Ann T; Walker, Brandon S; White, Kristie L; Wilson, Andrew R; Wojcik, Eva M; Yared, Marwan A; Factor, Rachel E
-Statistical literacy can be defined as understanding the statistical tests and terminology needed for the design, analysis, and conclusions of original research or laboratory testing. Little is known about the statistical literacy of clinical or anatomic pathologists. -To determine the statistical methods most commonly used in pathology studies from the literature and to assess familiarity and knowledge level of these statistical tests by pathology residents and practicing pathologists. -The most frequently used statistical methods were determined by a review of 1100 research articles published in 11 pathology journals during 2015. Familiarity with statistical methods was determined by a survey of pathology trainees and practicing pathologists at 9 academic institutions in which pathologists were asked to rate their knowledge of the methods identified by the focused review of the literature. -We identified 18 statistical tests that appear frequently in published pathology studies. On average, pathologists reported a knowledge level between "no knowledge" and "basic knowledge" of most statistical tests. Knowledge of tests was higher for more frequently used tests. Greater statistical knowledge was associated with a focus on clinical pathology versus anatomic pathology, having had a statistics course, having an advanced degree other than an MD degree, and publishing research. Statistical knowledge was not associated with length of pathology practice. -An audit of pathology literature reveals that knowledge of about 12 statistical tests would be sufficient to provide statistical literacy for pathologists. On average, most pathologists report they can interpret commonly used tests but are unable to perform them. Most pathologists indicated that they would benefit from additional statistical training.
James S McLay
Full Text Available Over the last decade academic interest in the prevalence and nature of herbal medicines use by pregnant women has increased significantly. Such data are usually collected by means of an administered questionnaire survey, however a key methodological limitation using this approach is the need to clearly define the scope of 'herbals' to be investigated. The majority of published studies in this area neither define 'herbals' nor provide a detailed checklist naming specific 'herbals' and CAM modalities, which limits inter-study comparison, generalisability and the potential for meta-analyses. The aim of this study was to compare the self-reported use of herbs, herbal medicines and herbal products using two different approaches implemented in succession.Cross-sectional questionnaire surveys of women attending for their mid-trimester scan or attending the postnatal unit following live birth at the Royal Aberdeen Maternity Hospital, North-East Scotland. The questionnaire utilised two approaches to collect data on 'herbals' use, a single closed yes/no answer to the question "have you used herbs, herbal medicines and herbal products in the last three months"; and a request to tick which of a list of 40 'herbals' they had used in the same time period.A total of 889 responses were obtained of which 4.3% (38 answered 'yes' to herbal use via the closed question. However, using the checklist 39% (350 of respondents reported the use of one or more specific 'herbals' (p<0.0001. The 312 respondents who reported 'no' to 'herbals' use via the closed question but "yes" via the checklist consumed a total of 20 different 'herbals' (median 1, interquartile range 1-2, range 1-6.This study demonstrates that the use of a single closed question asking about the use of 'herbals', as frequently reported in published studies, may not yield valid data resulting in a gross underestimation of actual use.
LaDonna, Kori A; Bates, Joanna; Tait, Glendon R; McDougall, Allan; Schulz, Valerie; Lingard, Lorelei
Complex, chronically ill patients require interprofessional teams to address their multiple health needs; heart failure (HF) is an iconic example of this growing problem. While patients are the common denominator in interprofessional care teams, patients have not explicitly informed our understanding of team composition and function. Their perspectives are crucial for improving quality, patient-centred care. To explore how individuals with HF conceptualize their care team, and perceive team members' roles. Individuals with advanced HF were recruited from five cities in three Canadian provinces. Individuals were asked to identify their HF care team during semi-structured interviews. Team members' titles and roles, quotes pertaining to team composition and function, and frailty criteria were extracted and analysed using descriptive statistics and content analysis. A total of 62 individuals with HF identified 2-19 team members. Caregivers, nurses, family physicians and cardiologists were frequently identified; teams also included dentists, foot care specialists, drivers, housekeepers and spiritual advisors. Most individuals met frailty criteria and described participating in self-management. Individuals with HF perceived being active participants, not passive recipients, of care. They identified teams that were larger and more diverse than traditional biomedical conceptualizations. However, the nature and importance of team members' roles varied according to needs, relationships and context. Patients' degree of agency was negotiated within this context, causing multiple, sometimes conflicting, responses. Ignoring the patient's role on the care team may contribute to fragmented care. However, understanding the team through the patient's lens - and collaborating meaningfully among identified team members - may improve health-care delivery. © 2016 The Authors. Health Expectations Published by John Wiley & Sons Ltd.
Resnik, David B; Tyler, Ana M; Black, Jennifer R; Kissling, Grace
We analysed the authorship policies of a random sample of 600 journals from the Journal Citation Reports database. 62.5% of the journals we sampled had an authorship policy. Having an authorship policy was positively associated with impact factor. Journals from the biomedical sciences and social sciences/humanities were more likely to have an authorship policy than journals from the physical sciences, engineering or mathematical sciences. Among journals with a policy, the most frequent type of policy was guidance on criteria for authorship (99.7%); followed by guidance on acknowledgments (97.3%); requiring that authors make substantial contributions to the research (94.7%); requiring that authors be accountable for the research as a whole (84.8%); guidance on changes in authorship (77.9%); requiring that authors give final approval to the manuscript (77.6%); requiring that authors draft or critically revise the manuscript (71.7%); providing guidance on corporate authorship (58.9%); prohibiting gift, guest or ghost authorship (31.7%); requiring authors to describe their contributions (5.3%); limiting the number of authors for some types of articles (4.0%) and requiring authors to be accountable for their part in the research (1.1%). None of the policies addressed equal contribution statements. Journals that do not have authorship policies should consider adopting or developing ones. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/
Cleveland, Gordon; Krashinsky, Michael
... of child care policy and asked them to consider a number of important questions. Based on a symposium on the topic held in 1998, Our Children's Future makes a significant contribution to understanding how Canada, with its particular institutions, history, politics, and values, should design a national child care strategy. Presenting a healthy and vigo...
Miller, Kevin J.; Morfidi, Eleni; Soulis, Spyros
Special education teachers and related service providers were interviewed for their perspectives on Greek special education policies and practices and how these influenced their job preparation and duties. Specifically, they were asked about the impact of the following on their jobs: Greek law related to the education of students with…
Schmidt, Johannes Dragsbæk; Christensen, Line Kikkenborg
This contribution analyzes how the intentions for social development activities within the area of health promotion through education are in conflict with outcomes. The paper asks; what are the discrepancies between policies intention at central level and the implementation on ‘the ground...
Viczko, Melody; Tascón, Clara I.
Internationalization processes are at the fore of university strategic plans on a global scale. However, the work of internationalization is being performed through the connections between many actors at different policy levels. Our purpose here is to ask, what is happening with internationalization of higher education at the Canadian national…
commissioners. Scoping studies are an essential element in the portfolio of approaches to research, particularly as a mechanism for helping research commissioners and policy makers to ask the right questions. Their utility will be further enhanced by greater recognition of the individual components, definitions for which are provided.
Feng, Hong; Cao, Jianlei; Zhang, Guangyu; Wang, Yanggan
Kaempferol has been demonstrated to provide benefits for the treatment of atherosclerosis, coronary heart disease, hyperlipidemia, and diabetes through its antioxidant and anti-inflammatory properties. However, its role in cardiac hypertrophy remains to be elucidated. The aim of our study was to investigate the effects of kaempferol on cardiac hypertrophy and the underlying mechanism. Mice subjected to aorta banding were treated with or without kaempferol (100 mg/kg/d, p. o.) for 6 weeks. Echocardiography was performed to evaluate cardiac function. Mice hearts were collected for pathological observation and molecular mechanism investigation. H9c2 cardiomyocytes were stimulated with or without phenylephrine for in vitro study. Kaempferol significantly attenuated cardiac hypertrophy induced by aorta banding as evidenced by decreased cardiomyocyte areas and interstitial fibrosis, accompanied with improved cardiac functions and decreased apoptosis. The ASK1/MAPK signaling pathways (JNK1/2 and p38) were markedly activated in the aorta banding mouse heart but inhibited by kaempferol treatment. In in vitro experiments, kaempferol also inhibited the activity of ASK1/JNK1/2/p38 signaling pathway and the enlargement of H9c2 cardiomyocytes. Furthermore, our study revealed that kaempferol could protect the mouse heart and H9c2 cells from pathological oxidative stress. Our investigation indicated that treatment with kaempferol protects against cardiac hypertrophy, and its cardioprotection may be partially explained by the inhibition of the ASK1/MAPK signaling pathway and the regulation of oxidative stress. Georg Thieme Verlag KG Stuttgart · New York.
Full Text Available A key research area in wireless transmission is underwater communications. It has a vital role in applications such as underwater sensor networks (UWSNs and disaster detection. The underwater channel is very unique as compared to other alternatives of transmission channels. It is characterized by path loss, multipath fading, Doppler spread and ambient noise. Thus, the bit error rate (BER is increased to a large extent when compared to its counterpart of cellular communications. Acoustic signals are the current best solution for underwater communications. The use of electromagnetic or optical waves obviously entails a much higher data rate. However, they suffer from high attenuation, absorption or scattering. This paper proposes a novel fractional fast Fourier transform (FrFT—orthogonal frequency division multiplexing (FrFT-OFDM system for underwater acoustic (UWA communication—which employs the amplitude shift keying (ASK modulation technique (FrFT-ASK-OFDM. Specifically, ASK achieves a better bandwidth efficiency as compared to other commonly used modulation techniques, such as quadrature amplitude modulation (QAM and phase shift keying (PSK. In particular, the system proposed in this article can achieve a very promising BER performance, and can reach higher data rates when compared to other systems proposed in the literature. The BER performance of the proposed system is evaluated numerically, and is compared to the corresponding M-ary QAM system in the UWA channel for the same channel conditions. Moreover, the performance of the proposed system is compared to the conventional fast Fourier transform (FFT-OFDM (FFT-OFDM system in the absence and presence of the effect of carrier frequency offset (CFO. Numerical results show that the proposed system outperforms the conventional FFT-based systems for UWA channels, even in channels dominated by CFO. Moreover, the spectral efficiency and data rate of the proposed system are approximately double
Post, Todd (Editor)
How big is your project world? Is it big enough to contain other cultures, headquarters, hierarchies, and weird harpoon-like guns? Sure it is. The great American poet Walt Whitman said it best, 'I am large/I contain multitudes.' And so must you, Mr. and Ms. Project Manager. In this issue of ASK, we look outside the project box. See how several talented project managers have expanded their definition of project scope to include managing environments outside the systems and subsystems under their care. Here's a sampling of what we've put together for you this issue: In 'Three Screws Missing,' Mike Skidmore tells about his adventures at the Plesetek Cosmodrome in northern Russia. Ray Morgan in his story, 'Our Man in Kauai,' suggests we take a broader view of what's meant by 'the team.' Jenny Baer-Riedhart, the NASA program manager on the same Pathfinder solar-powered airplane, schools us in how to sell a program to Headquarters in 'Know Thyself--But Don't Forget to Learn About the Customer Too.' Scott Cameron of Proctor and Gamble talks about sharpening your hierarchical IQ in 'The Project Manager and the Hour Glass.' Mike Jansen in 'The Lawn Dart' describes how he and the 'voodoo crew' on the Space Shuttle Advanced Solid Rocket Motor program borrowed a harpoon-like gun from the Coast Guard to catch particles inside of a plume. These are just some of the stories you'll find in ASK this issue. We hope they cause you to stop and reflect on your own project's relationship to the world outside. We are also launching a new section this issue, 'There are No Mistakes, Only Lessons.' No stranger to ASK readers, Terry Little inaugurates this new section with his article 'The Don Quixote Complex.'
Full Text Available We present ML-Ask – the first Open Source Affect Analysis system for textual input in Japanese. ML-Ask analyses the contents of an input (e.g., a sentence and annotates it with information regarding the contained general emotive expressions, specific emotional words, valence-activation dimensions of overall expressed affect, and particular emotion types expressed with their respective expressions. ML-Ask also incorporates the Contextual Valence Shifters model for handling negation in sentences to deal with grammatically expressible shifts in the conveyed valence. The system, designed to work mainly under Linux and MacOS, can be used for research on, or applying the techniques of Affect Analysis within the framework Japanese language. It can also be used as an experimental baseline for specific research in Affect Analysis, and as a practical tool for written contents annotation. Funding statement: This research has been supported by: a Research Grant from the Nissan Science Foundation (years 2009–2010, The GCOE Program founded by Japan’s Ministry of Education, Culture, Sports, Science and Technology (years 2009–2010, (JSPS KAKENHI Grant-in-Aid for JSPS Fellows (Project Number: 22-00358 (years 2010–2012, (JSPS KAKENHI Grant-in-Aid for Scientific Research (Project Number: 24600001 (years 2012–2015, (JSPS KAKENHI Grant-in-Aid for Research Activity Start-up (Project Number: 25880003 (years 2013–2015, and (JSPS KAKENHI Grant-in-Aid for Encouragement of Young Scientists (B (Project Number: 15K16044 (years 2015-present, project estimated to end in March 2018.