A critical look at spatial scale choices in satellite-based aerosol indirect effect studies

Science.gov (United States)

Grandey, B. S.; Stier, P.

2010-12-01

Analysing satellite datasets over large regions may introduce spurious relationships between aerosol and cloud properties due to spatial variations in aerosol type, cloud regime and synoptic regime climatologies. Using MODerate resolution Imaging Spectroradiometer data, we calculate relationships between aerosol optical depth τa derived liquid cloud droplet effective number concentration Ne and liquid cloud droplet effective radius re at different spatial scales. Generally, positive values of font-size: 10px; color: #000;">dlnNefont-size: 10px; color: #000;">dlnτa are found for ocean regions, whilst negative values occur for many land regions. The spatial distribution of font-size: 10px; color: #000;">dlnrefont-size: 10px; color: #000;">dlnτa shows approximately the opposite pattern, with generally postive values for land regions and negative values for ocean regions. We find that for region sizes larger than 4° × 4°, spurious spatial variations in retrieved cloud and aerosol properties can introduce widespread significant errors to calculations of font-size: 10px; color: #000;">dlnNefont-size: 10px; color: #000;">dlnτa and font-size: 10px; color: #000;">dlnrefont-size: 10px; color: #000;">dlnτa. For regions on the scale of 60° × 60°, these methodological errors may lead to an overestimate in global cloud albedo effect radiative forcing of order 80% relative to that calculated for regions on the scale of 1° × 1°.

Polyaniline/partially exfoliated multi-walled carbon nanotubes based nanocomposites for supercapacitors

International Nuclear Information System (INIS)

Potphode, Darshna D.; Sivaraman, P.; Mishra, Sarada P.; Patri, Manoranjan

2015-01-01

In the present study, polyaniline (PANI)/partially exfoliated multi-walled carbon nanotubes (Px-MWCNT) nanocomposites were investigated for supercapacitor application. Nanocomposites with varying weight/weight ratio of PANI and Px-MWCNT were prepared by in-situ polymerization of aniline over Px-MWCNT. Transmission and scanning electron microscopic analysis showed that the MWCNT was partial unzipped along the length of tubes. The morphology of PANI/Px-MWCNT nanocomposites exhibited wrapping of PANI over Px-MWCNT. Symmetric supercapacitors containing PANI/Px-MWCNT nanocomposites as the electrode material were fabricated. The electrochemical characterization of the nanocomposites was carried by two electrode method (unit cell configuration). Cyclic voltammetric analysis showed a synergistic increase in specific capacitance of the nanocomposites. Charge-discharge cycle study indicated that nanocomposites have greater charge-discharge rate capability than pure PANI. The observed result is attributed to the shorter diffusion length of ions in the nanocomposites as compared to that of pure PANI. The electrochemical impedance spectra of supercapacitors were resolved into real and losscapacitances. The loss capacitance indicated that the time constant of the nanocomposites decreases with increase in the Px-MWCNT content. The supercapacitors showed enhanced stability during continuous charge-discharge cycling as the PX-MWCNT content in the nanocomposites increased. PANI-50 and PANI-25 nanocomposites based supercapacitors exhibited 91% and 93% capacitive retention after 2000 charge-discharge cycle while pure PANI showed only 67% capacitance retention for the same number of cycles

Molecular Cloning and Characterization of a P-Glycoprotein from the Diamondback Moth, Plutella xylostella (Lepidoptera: Plutellidae)

Science.gov (United States)

Tian, Lixia; Yang, Jiaqiang; Hou, Wenjie; Xu, Baoyun; Xie, Wen; Wang, Shaoli; Zhang, Youjun; Zhou, Xuguo; Wu, Qingjun

2013-01-01

Macrocyclic lactones such as abamectin and ivermectin constitute an important class of broad-spectrum insecticides. Widespread resistance to synthetic insecticides, including abamectin and ivermectin, poses a serious threat to the management of diamondback moth, Plutella xylostella (L.) (Lepidoptera: Plutellidae), a major pest of cruciferous plants worldwide. P-glycoprotein (Pgp), a member of the ABC transporter superfamily, plays a crucial role in the removal of amphiphilic xenobiotics, suggesting a mechanism for drug resistance in target organisms. In this study, PxPgp1, a putative Pgp gene from P. xylostella, was cloned and characterized. The open reading frame (ORF) of PxPgp1 consists of 3774 nucleotides, which encodes a 1257-amino acid peptide. The deduced PxPgp1 protein possesses structural characteristics of a typical Pgp, and clusters within the insect ABCB1. PxPgp1 was expressed throughout all developmental stages, and showed the highest expression level in adult males. PxPgp1 was highly expressed in midgut, malpighian tubules and testes. Elevated expression of PxPgp1 was observed in P. xylostella strains after they were exposed to the abamectin treatment. In addition, the constitutive expressions of PxPgp1 were significantly higher in laboratory-selected and field-collected resistant strains in comparison to their susceptible counterpart. PMID:24264038

DNA repair characteristics of a hybrid cell clone between xeroderma pigmentosum and Potorous tridactilis

International Nuclear Information System (INIS)

Ida, Kenji

1986-01-01

A hybrid cell clone PX1 was isolated by fusing UV sensitive XP20S(SV)neo, an SV-40-transformed, neomycin-resistant xeroderma pigmentosum (XP) cell line, and Pt K2, a rat kangaroo (Potorous tridactilis) cell line. The UV-survival curve of PX1 cells fell midway between those of Pt K2 and XP20S(SV)neo cells, since mean lethal doses(D 0 ) were 2.5, 4.7 and 0.27 J/m 2 for PX1, Pt K2 and XP20S(SV)neo, respectively. Amounts of unscheduled DNA synthesis (UDS) after UV, relative to normal human cells, were 60.4 % for Pt K2, 37.7 % for PX1 and 0.1 % for XP20S(SV)neo. Such relative UDS capacities for excision repair of Pt K2, PX1 and XP20S(SV)neo were also consistent with the respective relative capacities of host cell reactivation (HCR) of UV-irradiated Herpes simplex virus. Apparently, there was no single Pt K2 chromosome in the PX1 cells. One possibility is that a gene which may account for the partial restoration of the UV resistance has been transferred from Pt K2 to PX1. (author)

Roberto Mantovani (1854-1933 and his ideas on the expanding Earth, as revealed by his correspondence and manuscripts

Directory of Open Access Journals (Sweden)

Giancarlo Scalera

2009-06-01

Full Text Available

px 0.0px 0.0px 0.0px; font: 9.0px Times;">Roberto Mantovani (Parma, 25 March 1854-Paris, 10 January 1933 – a musician and geologist trained in the Duchy of Parma – was a Consul in the French island of La Réunion at the end of the nineteenth century. In 1878 drawing general conclusions from the similarity in shape between the facing banks of a river that flowed in a volcanic fracture, and the way in which the layers corresponded, Mantovani formulated a mobilistic theory, attributing the moving apart of the continents to the expansion of the entire planet. This theory is more general than that of Wegener from the first decades of the following century. Mantovani’s hypothesis was officially recognised by the French Geological Society in 1924, which incorporated it in its body of legitimate ideas. Encouraged by Bourcart in 1924, Wegener quoted the Italian in his famous book as one who offered ideas extraordinarily close to his own. A letter of Mantovani to Wegener, and the sceptical answer of the German scientist, have been recently found. In his letter Mantovani shows a greater awareness of the predecessors of the continental drift than Wegener

px 0.0px 0.0px 0.0px; font: 9.0px Times;">himself. Mantovani continued to disseminate his idea up to the last years of his life. A final pamphlet, of 1930, was printed with this dedication: «to the mathematicians, physicists, astronomers, geologists, and anyone interested in the great enigmas of the Universe». is biography has been reconstructed thanks to the correspondences carefully conserved in the archives of the Italian Ministry of Foreign Affairs, the Ethnographic Museum Luigi Pigorini, the Società Geografica Italiana, and in the private files of his direct descendants.

Impact of pulsed xenon ultraviolet disinfection on surface contamination in a hospital facility's expressed human milk feed preparation area.

Science.gov (United States)

Dippenaar, Ricky; Smith, Johan

2018-02-23

Expressed human milk (EHM) feed preparation areas represent a potential source of unintentional nosocomial infection. Daily disinfection of environmental surfaces remains an essential intervention to mitigate nosocomial infections. The inefficiency of conventional cleaning and disinfection contributes to an increased risk for the acquisition of multi-drug resistant pathogens. "Non touch" technologies such as the pulsed xenon ultraviolet (PX-UVD) light device have documented sustained reduction in surface bacterial colonization and reduced cross contamination. The impact of a PX-UVD on surface colony forming units per square centimeter (cfu/cm 2 ) in feed preparation areas was evaluated following its implementation as standard care. A quasi-experimental study was performed documenting bacterial colonization from 6 high risk feed preparation areas in a community care hospital in South Africa. Pre and post conventional cleaning neutralizing rinse swabs were collected fortnightly over a 16 week control period prior to the introduction of the PX-UVD and compared to a matching set of samples for the PX-UVD period. A 90% reduction in total surface bioburden was noted from the control period (544 cfu/cm 2 ) compared to the corresponding PX-UVD period (50 cfu/cm 2 ). Sub -analysis of both the Pre-clean Control: Pre-clean PX-UVD counts as well as the Post-clean Control: Post-clean PX-UVD counts noted significant improvements (p cleaning total surface bioburden following exposure to the PX-UVD (p = 0.0004). The introduction of the PX-UVD was associated with a sustained reduction in the pre clean bioburden counts with a risk trend (per week) 0.19, (95% CI [0.056, 0.67], p = 0.01). The use of a PX-UVD as adjunct to standard cleaning protocols was associated with a significant decrease in surface bioburden. The study demonstrated the inefficiency of conventional cleaning. Persistence of potentially pathological species in both periods highlights current health

Impaired growth and force production in skeletal muscles of young partially pancreatectomized rats: a model of adolescent type 1 diabetic myopathy?

Directory of Open Access Journals (Sweden)

Carly S Gordon

Full Text Available This present study investigated the temporal effects of type 1 diabetes mellitus (T1DM on adolescent skeletal muscle growth, morphology and contractile properties using a 90% partial pancreatecomy (Px model of the disease. Four week-old male Sprague-Dawley rats were randomly assigned to Px (n = 25 or Sham (n = 24 surgery groups and euthanized at 4 or 8 weeks following an in situ assessment of muscle force production. Compared to Shams, Px were hyperglycemic (>15 mM and displayed attenuated body mass gains by days 2 and 4, respectively (both P<0.05. Absolute maximal force production of the gastrocnemius plantaris soleus complex (GPS was 30% and 50% lower in Px vs. Shams at 4 and 8 weeks, respectively (P<0.01. GP mass was 35% lower in Px vs Shams at 4 weeks (1.24±0.06 g vs. 1.93±0.03 g, P<0.05 and 45% lower at 8 weeks (1.57±0.12 vs. 2.80±0.06, P<0.05. GP fiber area was 15-20% lower in Px vs. Shams at 4 weeks in all fiber types. At 8 weeks, GP type I and II fiber areas were ∼25% and 40% less, respectively, in Px vs. Shams (group by fiber type interactions, P<0.05. Phosphorylation states of 4E-BP1 and S6K1 following leucine gavage increased 2.0- and 3.5-fold, respectively, in Shams but not in Px. Px rats also had impaired rates of muscle protein synthesis in the basal state and in response to gavage. Taken together, these data indicate that exposure of growing skeletal muscle to uncontrolled T1DM significantly impairs muscle growth and function largely as a result of impaired protein synthesis in type II fibers.

Protective effects of Punica granatum (pomegranate) peel extract on concanavalin A-induced autoimmune hepatitis in mice.

Science.gov (United States)

Wang, Tingting; Men, Ruoting; Hu, Mingxing; Fan, Xiaoli; Yang, Xiaoxue; Huang, Xiaojun; Ye, Tinghong; Yang, Li

2018-04-01

Autoimmune hepatitis (AIH) is a chronic inflammatory liver disease of an unknown etiology, glucocorticoid therapy is currently recognized as an effective treatment for AIH, but conventional application and patient compliance are both hindered by its side effects. The exploration of the AIH pathogenesis and the searching for the new candidate drugs that exert potential activity and low toxicity are urgently needed. Pomegranate peel extract (PoPx) is a natural extract of Punica granatum and has been reported to have anti-inflammatory and antioxidative properties. The present study aimed to clarify the effect of PoPx on the concanavalin A (ConA)-induced autoimmune hepatitis in a mouse model that is well established at 12h after tail vein injection with a dose of 20 mg/kg of ConA. C57BL/6 female mice were pretreated with PoPx (250 mg/kg, once daily for 3 days) followed by a ConA challenge. Pretreatment with PoPx significantly alleviated ConA-induced liver injury by down-regulating the levels of plasma alanine transaminase (ALT), aspartate transaminase (AST) and cytokine, including TNF-α, interferon (IFN) -γ and interleukin (IL)-6. Moreover, liver hematoxylin and eosin (H&E) staining displayed a lighter inflammatory infiltration around the portal area in the PoPx-pretreated mice. In addition, the flow cytometry (FCM) data showed that the immune response in the liver was died down in the PoPx-pretreated condition. Specially, pretreatment with PoPx reduced the infiltration of activated CD4 + and CD8 + T cells in the liver. Taken together, these findings contributed to a better understanding of the actions of PoPx against acute AIH and indicated that PoPx might be a potential compound in treating T cell-mediated autoimmune liver injury. Copyright © 2018 Elsevier Masson SAS. All rights reserved.

Tensor and vector analysing powers A{sub yy} and A{sub y} in the {sup 12}C(d, p)X and {sup 12}C(d, d)X reactions at initial deuteron momentum of 9 GeV/c and emission angle of 85 mrad

Energy Technology Data Exchange (ETDEWEB)

Afanas` ev, S V; Arkhipov, V V; Azhgirej, L S [Joint Institute for Nuclear Research, Dubna (Russian Federation); and others

1998-12-01

The first data on tensor and vector analysing powers A{sub yy} and A{sub y} in the {sup 12}C(d, p)X and {sup 12}C(d, d)X reactions have been obtained at incident deuteron momentum of 9 GeV/c and emission angle for the secondary particles of 85 mrad. The value of A{sub yy} in inclusive deuteron breakup remains positive at the highest measured momentum of proton, that is in contradiction with the predictions of the model using conventional deuteron wave functions. The values of A{sub y} in this reaction are small but non-negligible. The data on A{sub yy} and A{sub y} in deuteron inelastic scattering could bring new important information on the baryonic resonance properties in the vicinity of masses {approx}2.2 GeV/c{sup 2} 34 refs., 24 figs., 9 tabs.

A sensitive voltammetric detection of pramipexole based on 1,1,3,3-tetramethyldisilazanecarbon nanotube modified electrode

Energy Technology Data Exchange (ETDEWEB)

Amirighadi, Saeede [Electroanalytical Chemistry Research Laboratory, Department of Analytical Chemistry, Faculty of Chemistry, University of Mazandaran, Babolsar (Iran, Islamic Republic of); Raoof, Jahan Bakhsh, E-mail: j.raoof@umz.ac.ir [Electroanalytical Chemistry Research Laboratory, Department of Analytical Chemistry, Faculty of Chemistry, University of Mazandaran, Babolsar (Iran, Islamic Republic of); Department of Chemistry, Ayatollah Amoli Branch, Islamic Azad University, Amol (Iran, Islamic Republic of); Chekin, Fereshteh [Department of Chemistry, Ayatollah Amoli Branch, Islamic Azad University, Amol (Iran, Islamic Republic of); Ojani, Reza [Electroanalytical Chemistry Research Laboratory, Department of Analytical Chemistry, Faculty of Chemistry, University of Mazandaran, Babolsar (Iran, Islamic Republic of)

2017-06-01

A simple low-cost method is proposed to fabricate a functionalized multi-wall carbon nanotube (MWCNT) with 1,1,3,3-tetramethyldisilazane (TMDS) molecule. The techniques of scanning electron microscope (SEM) with electron diffraction and energy dispersive X-ray (EDAX) analysis were applied to characterize the functionalized TMDS-MWCNT. The results showed that a MWCNT with high functionalization of TMDS can be obtained using this simple method. A new nanostructure sensor was constructed based on a glassy carbon electrode modified with TMDS-MWCNT (TMDS-MWCNT/GCE). It was found that the TMDS-MWCNT/GCE exhibits good catalytic activity toward oxidation of pramipexole (PPX) drug, leading to a concentration range of 0.8 to 600 μM with a detection limit of 0.2 μM at 3σ using the differential pulse voltammetry technique, a sensitivity of 0.084 μA μM{sup −1}, and a correlation coefficient of 0.991. Furthermore, the TMDS-MWCNT/GCE was used for PPX detection in tablets and human blood serum samples. The method showed no interference from tablet excipients; hence, it can be useful and fit for the quantification of PPX in bulk and tablet dosage forms. The proposed method was validated successfully as applied to the quantification of the drug in tablet dosage forms. The accuracy of detection results using the proposed method was evaluated as excellent comparing with those obtained by the reference method. - Highlights: • The MWCNT was functionalized with TMDS molecule by a simple and low-cost method. • The new nanostructure sensor based on glassy carbon electrode modified with TMDS-MWCNT • It was found that TMDS-MWCNT/GCE exhibits good catalytic activity toward the oxidation of pramipexole. • This sensor showed concentration range of 0.8 to 600 μM with a detection limit of 0.2 μM. • The proposed method does not differ significantly in precision and accuracy from the reference method.

Cloning and functional identification of moricins from the diamondback moth, Plutella xylostella (L.).

Science.gov (United States)

Xia, X-F; Li, Y; Yu, X-Q; Lin, J-H; Li, S-Y; Li, Q; You, M-S

2017-10-01

Antimicrobial peptides (AMPs) are small-molecule peptides that play crucial roles in insect innate immune responses. To better understand the function of AMPs in Plutella xylostella, one of the main pests of cruciferous vegetables, three full-length cDNAs encoding moricins were cloned from Pl. xylostella. Two variants of the moricin named PxMor2 and PxMor3 were heterologously expressed and purified. A secondary structure analysis using circular dichroism demonstrated that the two peptides adopted an α-helical structure in the membrane-like environment, but in aqueous solution, they were present in random coiled conformation. Antimicrobial activity assays demonstrated that PxMor2 exhibited high activity against Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli; however, PxMor3 only demonstrated high activity against E. coli. Scanning electron microscopy and confocal laser-scanning microscopy analyses suggest that PxMors can lead to the disruption of bacterial membrane, which might be the mechanism by which PxMors inhibit bacterial growth. This study contributes to the understanding of Pl. xylostella AMPs and immune responses, and also enriches the knowledge of insect moricin. © 2017 The Royal Entomological Society.

Subklinik Laminitis ile İlgili Araştırmalar

OpenAIRE

Çeçen, Göksen

2014-01-01

 Tüm dünyada kabul edildiği üzere, topallıklar sığırlar için ciddi bir refah sorunudur. Sığır topallıklarının şekillenmesinde laminitis’in subklinik formunun önemli bir rol oynadığı kabul edilir. Hastalığın bu formu yaygın olup, teşhisi ise oldukça güçtür. Hayvanların bireysel olarak sağaltımları pratik olmadığı için, sürü genelinde hastalığa karşı gerekli tedbirler alınmalıdır. p.p1 {margin: 0.0px 0.0px 0.0px 0.0px; font: 12.0px 'Times New Roman'; min-height: 15.0...

Management and communication courses – Places available

CERN Multimedia

2014-01-01

Please note that there are some places available on the following management and communication courses starting in September or October.   For more information on the course, click on the course title, which will take you to the training catalogue. You can then sign up on line.  .tftable {color:#333333;width:100%;border-width: 1px;border-color: #a9a9a9;border-collapse: collapse;} .tftable th {background-color:#cdcdcd;border-width: 1px;padding: 8px;border-style: solid;border-color: #a9a9a9;text-align:left;} .tftable tr {background-color:#ffffff;} .tftable td {border-width: 1px;padding: 8px;border-style: solid;border-color: #a9a9a9;} Course Next session Duration Language Availability Managing Time 15 September 9 October 7 November 20 hours English 2 Managing Stress 6 October 7 October 16 hours English 5  

Quantitative Structure-Relative Volatility Relationship Model for Extractive Distillation of Ethylbenzene/p-Xylene Mixtures: Application to Binary and Ternary Mixtures as Extractive Agents

Energy Technology Data Exchange (ETDEWEB)

Kang, Young-Mook; Oh, Kyunghwan; You, Hwan; No, Kyoung Tai [Bioinformatics and Molecular Design Research Center, Seoul (Korea, Republic of); Jeon, Yukwon; Shul, Yong-Gun; Hwang, Sung Bo; Shin, Hyun Kil; Kim, Min Sung; Kim, Namseok; Son, Hyoungjun [Yonsei University, Seoul (Korea, Republic of); Chu, Young Hwan [Sangji University, Wonju (Korea, Republic of); Cho, Kwang-Hwi [Soongsil University, Seoul (Korea, Republic of)

2016-04-15

Ethylbenzene (EB) and p-xylene (PX) are important chemicals for the production of industrial materials; accordingly, their efficient separation is desired, even though the difference in their boiling points is very small. This paper describes the efforts toward the identification of high-performance extractive agents for EB and PX separation by distillation. Most high-performance extractive agents contain halogen atoms, which present health hazards and are corrosive to distillation plates. To avoid this disadvantage of extractive agents, we developed a quantitative structure-relative volatility relationship (QSRVR) model for designing safe extractive agents. We have previously developed and reported QSRVR models for single extractive agents. In this study, we introduce extended QSRVR models for binary and ternary extractive agents. The QSRVR models accurately predict the relative volatilities of binary and ternary extractive agents. The service to predict the relative volatility for binary and ternary extractive agents is freely available from the Internet at http://qsrvr.o pengsi.org/.

Quantitative Structure-Relative Volatility Relationship Model for Extractive Distillation of Ethylbenzene/p-Xylene Mixtures: Application to Binary and Ternary Mixtures as Extractive Agents

International Nuclear Information System (INIS)

Kang, Young-Mook; Oh, Kyunghwan; You, Hwan; No, Kyoung Tai; Jeon, Yukwon; Shul, Yong-Gun; Hwang, Sung Bo; Shin, Hyun Kil; Kim, Min Sung; Kim, Namseok; Son, Hyoungjun; Chu, Young Hwan; Cho, Kwang-Hwi

2016-01-01

Ethylbenzene (EB) and p-xylene (PX) are important chemicals for the production of industrial materials; accordingly, their efficient separation is desired, even though the difference in their boiling points is very small. This paper describes the efforts toward the identification of high-performance extractive agents for EB and PX separation by distillation. Most high-performance extractive agents contain halogen atoms, which present health hazards and are corrosive to distillation plates. To avoid this disadvantage of extractive agents, we developed a quantitative structure-relative volatility relationship (QSRVR) model for designing safe extractive agents. We have previously developed and reported QSRVR models for single extractive agents. In this study, we introduce extended QSRVR models for binary and ternary extractive agents. The QSRVR models accurately predict the relative volatilities of binary and ternary extractive agents. The service to predict the relative volatility for binary and ternary extractive agents is freely available from the Internet at http://qsrvr.o pengsi.org/.

Molecular Cloning and Characterization of the Calcineurin Subunit A from Plutella xylostella

Directory of Open Access Journals (Sweden)

Xi'en Chen

2013-10-01

Full Text Available Calcineurin (or PP2B has been reported to be involved in an array of physiological process in insects, and the calcineurin subunit A (CNA plays a central role in calcineurin activity. We cloned the CNA gene from Plutella xylostella (PxCNA. This gene contains an ORF of 1488 bp that encodes a 495 amino acid protein, showing 98%, and 80% identities to the CNA of Bombyx mori, and humans respectively. The full-length of PxCNA and its catalytic domain (CNA1–341, defined as PxCNα were both expressed in Escherichia coli. Purified recombinant PxCNA displayed no phosphatase activity, whereas recombinant PxCNα showed high phosphatase activity with a Km of 4.6 mM and a kcat of 0.66 S−1 against pNPP. It could be activated at different degrees by Mn2+, Ni2+, Mg2+, and Ca2+. The optimum reaction pH was about 7.5 and the optimum reaction temperature was around 45 °C. An in vitro inhibition assay showed that okadaic acid (OA and cantharidin (CTD competitively inhibited recombinant PxCNα activity with the IC50 values of 8.95 μM and 77.64 μM, respectively. However, unlike previous reports, pyrethroid insecticides were unable to inhibit recombinant PxCNα, indicating that the P. xylostella calcineurin appears not to be sensitive to class II pyrethroid insecticides.

The extract from Punica granatum (pomegranate) peel induces apoptosis and impairs metastasis in prostate cancer cells.

Science.gov (United States)

Deng, Yuanle; Li, Yali; Yang, Fangfang; Zeng, Anqi; Yang, Shuping; Luo, Yi; Zhang, Yiwen; Xie, Yongmei; Ye, Tinghong; Xia, Yong; Yin, Wenya

2017-09-01

Prostate cancer is a big threat to male for its poor prognosis and high mortality rate. Natural compounds are important resources of many anticancer drugs. Pomegranate is a kind of antioxidant-rich fruit and its peel and seed has potential anticancer activities. In this study, we aimed to investigate the effects of pomegranate peel extract (PoPx) on the apoptosis and metastasis of prostate cancer cells and the related mechanism. We found that PoPx showed growth inhibition on prostate cancer cells. Nuclei morphological and flow cytometer (FCM) analysis indicated that PoPx could induce prostate cancer apoptosis. Further investigation indicated that mitochondrial mediated intrinsic pathway is involved in the apoptosis. Exposure to PoPx led to loss of mitochondrial transmembrane potential (Δym), accumulation of reactive oxygen species (ROS). Western blot analysis showed that PoPx could increase the expression ratio of Bax/Bcl2 and activation of apoptosis executor caspase 3. Wound healing assay and transwell migration and invasion assay implied that PoPx has the potential to inhibit migration and invasion, two critical steps in prostate cancer metastasis. Downregulation of MMP2/MMP9 and upregulation of TIMP2 showed accordance with the inhibition of migration and invasion. In summary, the present data showed that PoPx could be a promising drug candidate to treat prostate cancer, showing us a better way to develop novel drugs from natural compounds. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

Continuous stroke unit electrocardiographic monitoring versus 24-hour Holter electrocardiography for detection of paroxysmal atrial fibrillation after stroke.

Science.gov (United States)

Rizos, Timolaos; Güntner, Janina; Jenetzky, Ekkehart; Marquardt, Lars; Reichardt, Christine; Becker, Rüdiger; Reinhardt, Roland; Hepp, Thomas; Kirchhof, Paulus; Aleynichenko, Elena; Ringleb, Peter; Hacke, Werner; Veltkamp, Roland

2012-10-01

Cardioembolism in paroxysmal atrial fibrillation (pxAF) is a frequent cause of ischemic stroke. Sensitive detection of pxAF after stroke is crucial for adequate secondary stroke prevention; the optimal diagnostic modality to detect pxAF on stroke units is unknown. We compared 24-hour Holter electrocardiography (ECG) with continuous stroke unit ECG monitoring (CEM) for pxAF detection. Patients with acute ischemic stroke or transient ischemic attack were prospectively enrolled. After a 12-channel ECG on admission, all patients received 24-hour Holter ECG and CEM. Additionally, ECG monitoring data underwent automated analysis using dedicated software to identify pxAF. Patients with a history of atrial fibrillation or with atrial fibrillation on the admission ECG were excluded. Four hundred ninety-six patients (median age, 69 years; 61.5% male) fulfilled all inclusion criteria (ischemic stroke: 80.4%; transient ischemic attack: 19.6%). Median stroke unit stay lasted 88.8 hours (interquartile range, 65.0-122.0). ECG data for automated CEM analysis were available for a median time of 64.0 hours (43.0-89.8). Paroxysmal AF was documented in 41 of 496 patients (8.3%). Of these, Holter detected pxAF in 34.1%; CEM in 65.9%; and automated CEM in 92.7%. CEM and automated CEM detected significantly more patients with pxAF than Holter (Pstroke on stroke units compared with 24-hour Holter ECG. The comparative usefulness of prolonged or repetitive Holter ECG recordings requires further evaluation.

An analysis of radioisotope power systems using improved ATEC cells

International Nuclear Information System (INIS)

El-Genk, M.S.; Tournier, J.M.

1998-01-01

Recently, a ground demo of eight AMTEC (PX-3G) cells has been tested successfully in vacuum at the Air Force Research laboratory (AFRL). Results showed that the electric power output and voltage of the best performing PX-3G cell are short of meeting the requirements of the Pluto/Express (PX) mission. Using the basic configuration of the PX-3G cell, several design changes are explored, to improve the cell performance. Also, several integration options of the improved PX-3G cells with General-Purpose Heat Source (GPHS) modules are investigated for an electric power level of 130 W e and a 15-year mission. The options explored include varying the number of GPHS modules and AMTEC cells, and using fresh or aged fuel. The effects of changing the generators' output voltage (24 V or 28 V) on the evaporator and BASE metal-ceramic brazes temperatures and temperature margin in the cell are also examined

N6-(2-Hydroxyethyl)-Adenosine Exhibits Insecticidal Activity against Plutella xylostella via Adenosine Receptors.

Science.gov (United States)

Fang, Ming; Chai, Yiqiu; Chen, Guanjv; Wang, Huidong; Huang, Bo

The diamondback moth, Plutella xylostella, is one of the most important pests of cruciferous crops. We have earlier shown that N6-(2-hydroxyethyl)-adenosine (HEA) exhibits insecticidal activity against P. xylostella. In the present study we investigated the possible mechanism of insecticidal action of HEA on P. xylostella. HEA is a derivative of adenosine, therefore, we speculated whether it acts via P. xylostella adenosine receptor (PxAdoR). We used RNAi approach to silence PxAdoR gene and used antagonist of denosine receptor (AdoR) to study the insecticidal effect of HEA. We cloned the whole sequence of PxAdoR gene. A BLAST search using NCBI protein database showed a 61% identity with the Drosophila adenosine receptor (DmAdoR) and a 32-35% identity with human AdoR. Though the amino acids sequence of PxAdoR was different compared to other adenosine receptors, most of the amino acids that are known to be important for adenosine receptor ligand binding and signaling were present. However, only 30% binding sites key residues was similar between PxAdoR and A1R. HEA, at a dose of 1 mg/mL, was found to be lethal to the second-instar larvae of P. xylostella, and a significant reduction of mortality and growth inhibition ratio were obtained when HEA was administered to the larvae along with PxAdoR-dsRNA or antagonist of AdoR (SCH58261) for 36, 48, or 60 h. Especially at 48 h, the rate of growth inhibition of the PxAdoR knockdown group was 3.5-fold less than that of the HEA group, and the corrected mortality of SCH58261 group was reduced almost 2-fold compared with the HEA group. Our findings show that HEA may exert its insecticidal activity against P. xylostella larvae via acting on PxAdoR.

Study on inclusion interaction of piroxicam with β-cyclodextrin derivatives

Science.gov (United States)

Xiliang, Guo; Yu, Yang; Guoyan, Zhao; Guomei, Zhang; Jianbin, Chao; Shaomin, Shuang

2003-12-01

The inclusion behavior of piroxicam (PX) with β-cyclodextrin (β-CD), hydroxypropyl-β-cyclodextrin (HP-β-CD), and carboxymethyl-β-cyclodextrin (CM-β-CD) was investigated by using steady-state fluorescence and nuclear magnetic resonance (NMR) technique. The various factors affecting the inclusion process were examined in detail. The remarkable fluorescence emission enhancement upon addition of CDs suggested that cyclodextrins (CDs) were most suitable for inclusion of the uncharged species of PX. The stoichiometry of the PX-CDs inclusion complexes was 1:1, except for β-CD where a 1:2 inclusion complex was formed. The formation constants showed the strongest inclusion capacity of β-CD. NMR showed the inclusion mode of PX with CDs.

miRNAs regulated overexpression of ryanodine receptor is involved in chlorantraniliprole resistance in Plutella xylostella (L.)

Science.gov (United States)

Li, Xiuxia; Guo, Lei; Zhou, Xuguo; Gao, Xiwu; Liang, Pei

2015-01-01

The amino acid mutations in ryanodine receptor (RyR) and elevated activity of detoxification enzymes have been associated with the diamide insecticide resistance in the diamondback moth, Plutella xylostella (L.). The up-regulation of P. xylostella RyR mRNA (PxRyR) expression has also been reported in field populations of different graphical origin. However, whether the up-regulation of PxRyR is involved in diamide resistance remains unknown. In this paper, 2.28- to 4.14-fold higher expression of PxRyR was detected in five field collected resistant populations, compared to that in a susceptible population. The expression of PxRyR was up-regulated 5.0- and 7.2-fold, respectively, after P. xylostella was treated with LC50 and LC75 of chlorantraniliprole for 12 h. Suppression of PxRyR using RNA interference restored the toxicity of chlorantraniliprole against the fourth instar larvae from the resistant population. More importantly, the expression of PxRyR is regulated by two miRNAs, miR-7a and miR-8519. These findings provide an empirical evidence of the involvement of miRNAs in the regulation of insecticide resistance, and shed light on the novel targets for the sustainable management of this devastating insect pest. PMID:26370154

Is the pulsed xenon ultraviolet light no-touch disinfection system effective on methicillin-resistant Staphylococcus aureus in the absence of manual cleaning?

Science.gov (United States)

Jinadatha, Chetan; Villamaria, Frank C; Restrepo, Marcos I; Ganachari-Mallappa, Nagaraja; Liao, I-Chia; Stock, Eileen M; Copeland, Laurel A; Zeber, John E

2015-08-01

Methicillin-resistant Staphylococcus aureus (MRSA) has been shown to survive on ambient surfaces for extended periods of time. Leftover MRSA environmental contamination in a hospital room places future patients at risk. Manual disinfection supplemented by pulsed xenon ultraviolet (PX-UV) light disinfection has been shown to greatly decrease the MRSA bioburden in hospital rooms. However, the effect of PX-UV in the absence of manual disinfection has not been evaluated. Rooms that were previously occupied by a MRSA-positive patient (current colonization or infection) were selected for the study immediately postdischarge. Five high-touch surfaces were sampled, before and after PX-UV disinfection, in each hospital room. The effectiveness of the PX-UV device on the concentration of MRSA was assessed employing a Wilcoxon signed-rank test for all 70 samples with MRSA in 14 rooms, as well as by surface location. The final analysis included 14 rooms. Before PX-UV disinfection there were a total of 393 MRSA colonies isolated from the 5 high-touch surfaces. There were 100 MRSA colonies after disinfection by the PX-UV device and the overall reduction was statistically significant (P disinfection. These findings are important for hospital and environmental services supervisors who plan to adapt new technologies as an adjunct to routine manual disinfection. Published by Elsevier Inc.

Survivability as a Tool for Evaluating Open Source Software

Science.gov (United States)

2015-06-01

tremendously successful in certain applications such as the Mozilla Firefox web browser and the Apache web server [10]. Open source software is often...source versions (such as Internet Explorer compared to Mozilla Firefox ), which typically conclude that vulnerabilities are, in fact, much more...for radios M. Smith ACS ACS ROS autonomous functionality (none) ACS PX4 Firmware PX4 FMU driver BSD 3-clause ACS PX4 Nuttx real time OS BSD ACS

Wrox SharePoint 2010 SharePoint911 three-pack

CERN Document Server

Klindt, Todd; Mason, Jennifer; Rogers, Laura; Drisgill, Randy; Ross, John; Riemann, Larry; Perran, Amanda; Perran, Shane; Sanford, Jacob J; Stubbs, Paul; Caravajal, Steve

2012-01-01

The Wrox SharePoint 2010 SharePoint911 Three-Pack combines the contents of three full e-books written by the experts from SharePoint911.  That's over 1800 pages of hands-on advice from Todd Klindt, Shane Young, Laura Rogers, Randy Drisgill, Jennifer Mason, John Ross, and Larry Riemann, among others. In Beginning SharePoint 2010: Building Business Solutions with SharePoint (ISBN 978-0-470-61789-2) by Amanda Perran, Shane Perran, Jennifer Mason, and Laura Rogers, readers learn the core concepts, terminology, and features of SharePoint 2010. In Professiona

The Utilization of Advanced Composites in Military Aircraft Held in San Diego, California on 7-11 October 1991 (L’Emploi des Materiaux Composites de Pointe pour les Avions Militaires)

Science.gov (United States)

1992-04-01

layered media , a (4.17). we may express this as for example in Kennett 191. P(x,,0) - exp((x,- -1 )Rr)exa(hr -1 R-., The advantage of the formulation...riuinii.iiuL-e S.P 11(17 .IS 1- 4(19 I hic ’’oict i 0i .1t I CL 101 irk .1rujiiiuuiid int tetd IC t 11 R It Krieger. filIe RV(iiitifl htst ~k:’ rI lir i;C

Beginning SharePoint 2010 Administration Windows SharePoint Foundation 2010 and Microsoft SharePoint Server 2010

CERN Document Server

Husman, Göran

2010-01-01

Complete coverage on the latest advances in SharePoint 2010 administration. SharePoint 2010 comprises an abundance of new features, and this book shows you how to take advantage of all SharePoint 2010's many improvements. Written by a four-time SharePoint MVP, Beginning SharePoint 2010 Administration begins with a comparison of SharePoint 2010 compared to the previous version and then examines the differences between WSS 4.0 and MSS 2010. Packed with step-by-step instructions, tips and tricks, and real-world examples, this book dives into the basics of how to install, manage, and administrate

May 2002 Lidar Point Data of Southern California Coastline: Dana Point to Point La Jolla

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains lidar point data from a strip of Southern California coastline (including water, beach, cliffs, and top of cliffs) from Dana Point to Point La...

September 2002 Lidar Point Data of Southern California Coastline: Dana Point to Point La Jolla

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains lidar point data from a strip of Southern California coastline (including water, beach, cliffs, and top of cliffs) from Dana Point to Point La...

Effects of low-dose cyclophosphamide with piroxicam on tumour neovascularization in a canine oral malignant melanoma-xenografted mouse model.

Science.gov (United States)

Choisunirachon, N; Jaroensong, T; Yoshida, K; Saeki, K; Mochizuki, M; Nishimura, R; Sasaki, N; Nakagawa, T

2015-12-01

Low-dose cyclophosphamide (CyLD) has shown promise in the treatment of several cancers; however, the effect of CyLD on canine oral malignant melanoma has never been explored. In this study, we investigated the effects of CyLD with or without piroxicam (Px) on tumour neovascularization and vascular normalization in a canine oral malignant melanoma-xenografted mice model. After treatment with CyLD, Px or a combination of both (CyPx), the growth of the tumour in the treatment groups was significantly suppressed compared to the control group at 30 days of treatment. Proliferation index was also significantly reduced by all treatments, only CyPx significantly lowered microvessel density and vascular endothelial growth factor (VEGF) levels. Additionally, CyLD significantly reduced the proportion of normal vessels and caused an imbalance between VEGF and thrombospondin-1. These results suggested that CyPx has potent anti-angiogenic effects in terms of both the number and quality of blood vessels in xenografted canine oral malignant melanoma. © 2013 John Wiley & Sons Ltd.

Identification and characterisation of multiple glutathione S-transferase genes from the diamondback moth, Plutella xylostella.

Science.gov (United States)

Chen, Xi'en; Zhang, Ya-lin

2015-04-01

The diamondback moth (DBM), Plutella xylostella, is one of the most harmful insect pests on crucifer crops worldwide. In this study, 19 cDNAs encoding glutathione S-transferases (GSTs) were identified from the genomic and transcriptomic database for DBM (KONAGAbase) and further characterized. Phylogenetic analysis showed that the 19 GSTs were classified into six different cytosolic classes, including four in delta, six in epsilon, three in omega, two in sigma, one in theta and one in zeta. Two GSTs were unclassified. RT-PCR analysis revealed that most GST genes were expressed in all developmental stages, with higher expression in the larval stages. Six DBM GSTs were expressed at the highest levels in the midgut tissue. Twelve purified recombinant GSTs showed varied enzymatic properties towards 1-chloro-2,4-dinitrobenzene and glutathione, whereas rPxGSTo2, rPxGSTz1 and rPxGSTu2 had no activity. Real-time quantitative PCR revealed that expression levels of the 19 DBM GST genes were varied and changed after exposure to acephate, indoxacarb, beta-cypermethrin and spinosad. PxGSTd3 was significantly overexpressed, while PxGSTe3 and PxGSTs2 were significantly downregulated by all four insecticide exposures. The changes in DBM GST gene expression levels exposed to different insecticides indicate that they may play individual roles in tolerance to insecticides and xenobiotics. © 2014 Society of Chemical Industry.

The Effect of Paroxetine on Ouabain-Induced Toxicity in Isolated Guinea Pig Atria

Directory of Open Access Journals (Sweden)

Farzaneh Najar

2011-04-01

Full Text Available It has been reported that selective serotonin reuptake inhibitors (SSRIs possess some cardiac effects. In the present study we have investigated the effect of paroxetine (PX, a potent SSRI agent, on spontaneously as well as ouabain-induced arrhythmia beating isolated guinea-pig atria. The Guinea-pig heart was rapidly removed; the auricles were dissected out in oxygenated modified Krebs solution. The rate and force of spontaneous contractions were recorded isometrically with a photosensitive transducer. PX (1-16 µg/ml caused a dose-dependent decrease in the rate of contractions (14-70% and contractile force (8-16%. Ouabain alone (1.2 µg/ml produced arrhythmia at 7.2 ± 1.5 min and asystole at 20.1 ± 3.1 min. Pretreatment with PX (4 µg/ml significantly increased the time of arrhythmia onset to 19.8 min. In addition, PX prolonged the duration of action beating from 20.1 ± 3.1 min to 43.1± 2.6 and delayed the occurrence of asystole. The pattern of contractile force by PX + ouabain treatment was more regular than that observed after administration of ouabain alone. The above findings may the probably be due to the inhibition of cardiac Na+ and Ca2+ channels or autonomic nervous system. Results also suggest that PX may reduce the membrane conductance through inhibition of ionic channels to prevent ouabain-induced arrhythmia.

Investigation of glutathione peroxidase activity in chicken meat under different experimental conditions Investigação da atividade de glutationa peroxidase em carne de frango submetida a diferentes condições experimentais

Directory of Open Access Journals (Sweden)

Alexandre José Cichoski

2012-12-01

Full Text Available Due to the fact that previous studies on the enzymatic activity of Glutathione peroxidase (GSH-Px diverge widely in their methodology and results, this study aimed to investigate the influence of different analytical conditions on GSH-Px activity in chicken thighs from broilers that were fed different diets with different sources and concentrations of selenium. GSH-Px activity was evaluated six hours after slaughter and 120 days after frozen storage at -18 ºC. The different analytical conditions included time of pre-incubation (0, 10 and 30 minutes, reaction medium, types of substrate (H2O2 (0.72 mM, 7.2 mM, and 72 mM and Terc-butil hydroperoxide 15 mM, and different buffer concentrations (buffer 1, potassium phosphate 50 mM pH 7.0 + EDTA 1 mM + mercaptoethanol 1 mM, and buffer 2, tris-HCl 50 mM pH 7.6 + EDTA 1 mM + mercapthanol 5 mM. The results show that the highest GSH-Px activity was observed when enzyme and substrate were in contact at 22 ºC without any pre-incubation, and that, when used at concentrations above 0.72 mM, hydrogen peroxide saturated the GSH-Px enzyme and inhibited its activity. The enzyme presented higher affinity to hydrogen peroxide when compared to terc-butil peroxide, and the addition of a buffer containing mercaptoethanol did not increase GSH-Px enzymatic activity. The activity of GSH-Px was not influenced by the source and concentration of selenium in the diet either. The obtained results allowed the determination of the best temperature of contact between the enzyme and substrate (22 ºC, the optimum concentration, and the type of substrate and buffer to be used. This information is extremely useful for future studies on GSH-Px activity in meat due to the divergence and little information found in the literature.Uma vez que estudos anteriores sobre a atividade enzimática da glutationa peroxidase (GSH-Px divergem acerca da metodologia e dos resultados, este estudo teve por objetivo investigar a influência de

Existence of solutions for a fourth order eigenvalue problem ] {Existence of solutions for a fourth order eigenvalue problem with variable exponent under Neumann boundary conditions

Directory of Open Access Journals (Sweden)

Khalil Ben Haddouch

2016-04-01

Full Text Available In this work we will study the eigenvalues for a fourth order elliptic equation with $p(x$-growth conditions $\\Delta^2_{p(x} u=\\lambda |u|^{p(x-2} u$, under Neumann boundary conditions, where $p(x$ is a continuous function defined on the bounded domain with $p(x>1$. Through the Ljusternik-Schnireleman theory on $C^1$-manifold, we prove the existence of infinitely many eigenvalue sequences and $\\sup \\Lambda =+\\infty$, where $\\Lambda$ is the set of all eigenvalues.

Effects of transcranial direct current stimulation on hemichannel pannexin-1 and neural plasticity in rat model of cerebral infarction.

Science.gov (United States)

Jiang, T; Xu, R X; Zhang, A W; Di, W; Xiao, Z J; Miao, J Y; Luo, N; Fang, Y N

2012-12-13

The aim of this study was to investigate the effects of transcranial direct current stimulation (TDCS) on hemichannel pannexin-1 (PX1) in cortical neurons and neural plasticity, and explore the optimal time window of TDCS therapy after stroke. Adult male Sprague-Dawley rats (n=90) were randomly assigned to sham operation, middle cerebral artery occlusion (MCAO), and TDCS groups, and underwent sham operation, unilateral middle cerebral artery (MCA) electrocoagulation, and unilateral MCA electrocoagulation plus TDCS (daily anodal and cathodal 10 Hz, 0.1 mA TDCS for 30 min beginning day 1 after stroke), respectively. Motor function was assessed using the beam walking test (BWT), and density of dendritic spines (DS) and PX1 mRNA expression were compared among groups on days 3, 7, and 14 after stroke. Effects of PX1 blockage on DS in hippocampal neurons after hypoxia-ischemia were observed. TDCS significantly improved motor function on days 7 and 14 after stroke as indicated by reduced BWT scores compared with the MCAO group. The density of DS was decreased after stroke; the TDCS group had increased DS density compared with the MCAO group on days 3, 7, and 14 (all P<0.0001). Cerebral infarction induced increased PX1 mRNA expression on days 3, 7, and 14 (P<0.0001), and the peak PX1 mRNA expression was observed on day 7. TDCS did not decrease the up-regulated PX1 mRNA expression after stroke on day 3, but did reduce the increased post-stroke PX1 mRNA expression on days 7 and 14 (P<0.0001). TDCS increased the DS density after stroke, indicating that it may promote neural plasticity after stroke. TDCS intervention from day 7 to day 14 after stroke demonstrated motor function improvement and can down-regulate the elevated PX1 mRNA expression after stroke. Copyright © 2012 IBRO. Published by Elsevier Ltd. All rights reserved.

N6-(2-Hydroxyethyl)-Adenosine Exhibits Insecticidal Activity against Plutella xylostella via Adenosine Receptors

Science.gov (United States)

Fang, Ming; Chai, Yiqiu; Chen, Guanjv; Wang, Huidong; Huang, Bo

2016-01-01

The diamondback moth, Plutella xylostella, is one of the most important pests of cruciferous crops. We have earlier shown that N6-(2-hydroxyethyl)-adenosine (HEA) exhibits insecticidal activity against P. xylostella. In the present study we investigated the possible mechanism of insecticidal action of HEA on P. xylostella. HEA is a derivative of adenosine, therefore, we speculated whether it acts via P. xylostella adenosine receptor (PxAdoR). We used RNAi approach to silence PxAdoR gene and used antagonist of denosine receptor (AdoR) to study the insecticidal effect of HEA. We cloned the whole sequence of PxAdoR gene. A BLAST search using NCBI protein database showed a 61% identity with the Drosophila adenosine receptor (DmAdoR) and a 32–35% identity with human AdoR. Though the amino acids sequence of PxAdoR was different compared to other adenosine receptors, most of the amino acids that are known to be important for adenosine receptor ligand binding and signaling were present. However, only 30% binding sites key residues was similar between PxAdoR and A1R. HEA, at a dose of 1 mg/mL, was found to be lethal to the second-instar larvae of P. xylostella, and a significant reduction of mortality and growth inhibition ratio were obtained when HEA was administered to the larvae along with PxAdoR-dsRNA or antagonist of AdoR (SCH58261) for 36, 48, or 60 h. Especially at 48 h, the rate of growth inhibition of the PxAdoR knockdown group was 3.5-fold less than that of the HEA group, and the corrected mortality of SCH58261 group was reduced almost 2-fold compared with the HEA group. Our findings show that HEA may exert its insecticidal activity against P. xylostella larvae via acting on PxAdoR. PMID:27668428

Investigation of glutathione peroxidase activity in chicken meat under different experimental conditions

Directory of Open Access Journals (Sweden)

Alexandre José Cichoski

2012-12-01

Full Text Available Due to the fact that previous studies on the enzymatic activity of Glutathione peroxidase (GSH-Px diverge widely in their methodology and results, this study aimed to investigate the influence of different analytical conditions on GSH-Px activity in chicken thighs from broilers that were fed different diets with different sources and concentrations of selenium. GSH-Px activity was evaluated six hours after slaughter and 120 days after frozen storage at -18 ºC. The different analytical conditions included time of pre-incubation (0, 10 and 30 minutes, reaction medium, types of substrate (H2O2 (0.72 mM, 7.2 mM, and 72 mM and Terc-butil hydroperoxide 15 mM, and different buffer concentrations (buffer 1, potassium phosphate 50 mM pH 7.0 + EDTA 1 mM + mercaptoethanol 1 mM, and buffer 2, tris-HCl 50 mM pH 7.6 + EDTA 1 mM + mercapthanol 5 mM. The results show that the highest GSH-Px activity was observed when enzyme and substrate were in contact at 22 ºC without any pre-incubation, and that, when used at concentrations above 0.72 mM, hydrogen peroxide saturated the GSH-Px enzyme and inhibited its activity. The enzyme presented higher affinity to hydrogen peroxide when compared to terc-butil peroxide, and the addition of a buffer containing mercaptoethanol did not increase GSH-Px enzymatic activity. The activity of GSH-Px was not influenced by the source and concentration of selenium in the diet either. The obtained results allowed the determination of the best temperature of contact between the enzyme and substrate (22 ºC, the optimum concentration, and the type of substrate and buffer to be used. This information is extremely useful for future studies on GSH-Px activity in meat due to the divergence and little information found in the literature.

Address Points - COUNTY_ADDRESS_POINTS_IDHS_IN: Address Points Maintained by County Agencies in Indiana (Indiana Department of Homeland Security, Point feature class)

Data.gov (United States)

NSGIC State | GIS Inventory — COUNTY_ADDRESS_POINTS_IDHS_IN is an ESRI Geodatabase point feature class that contains address points maintained by county agencies in Indiana, provided by personnel...

Analysis of characteristic performance curves in radiodiagnosis by an observer

International Nuclear Information System (INIS)

Kossovoj, A.L.

1988-01-01

Methods and ways of construction of performance characteristic curves (PX-curves) in roentgenology, their qualitative and quantitative estimation are described. Estimation of PX curves application for analysis of scintigraphic and sonographic images is presented

Beginning SharePoint 2010 Building Business Solutions with SharePoint

CERN Document Server

Perran, Amanda; Mason, Jennifer; Rogers, Laura

2010-01-01

Two SharePoint MVPs provide the ultimate introduction to SharePoint 2010Beginning SharePoint 2010: Building Team Solutions with SharePoint provides information workers and site managers with extensive knowledge and expert advice, empowering them to become SharePoint champions within their organizations.Provides expansive coverage of SharePoint topics, as well as specialty areas such as forms, excel services, records management, and web content managementDetails realistic usage scenarios, and includes practice examples that highlight best practices for configuration and customizationIncludes de

Mutual synergy between catalase and peroxidase activities of the bifunctional enzyme KatG is facilitated by electron hole-hopping within the enzyme.

Science.gov (United States)

Njuma, Olive J; Davis, Ian; Ndontsa, Elizabeth N; Krewall, Jessica R; Liu, Aimin; Goodwin, Douglas C

2017-11-10

KatG is a bifunctional, heme-dependent enzyme in the front-line defense of numerous bacterial and fungal pathogens against H 2 O 2 -induced oxidative damage from host immune responses. Contrary to the expectation that catalase and peroxidase activities should be mutually antagonistic, peroxidatic electron donors (PxEDs) enhance KatG catalase activity. Here, we establish the mechanism of synergistic cooperation between these activities. We show that at low pH values KatG can fully convert H 2 O 2 to O 2 and H 2 O only if a PxED is present in the reaction mixture. Stopped-flow spectroscopy results indicated rapid initial rates of H 2 O 2 disproportionation slowing concomitantly with the accumulation of ferryl-like heme states. These states very slowly returned to resting ( i.e. ferric) enzyme, indicating that they represented catalase-inactive intermediates. We also show that an active-site tryptophan, Trp-321, participates in off-pathway electron transfer. A W321F variant in which the proximal tryptophan was replaced with a non-oxidizable phenylalanine exhibited higher catalase activity and less accumulation of off-pathway heme intermediates. Finally, rapid freeze-quench EPR experiments indicated that both WT and W321F KatG produce the same methionine-tyrosine-tryptophan (MYW) cofactor radical intermediate at the earliest reaction time points and that Trp-321 is the preferred site of off-catalase protein oxidation in the native enzyme. Of note, PxEDs did not affect the formation of the MYW cofactor radical but could reduce non-productive protein-based radical species that accumulate during reaction with H 2 O 2 Our results suggest that catalase-inactive intermediates accumulate because of off-mechanism oxidation, primarily of Trp-321, and PxEDs stimulate KatG catalase activity by preventing the accumulation of inactive intermediates. © 2017 by The American Society for Biochemistry and Molecular Biology, Inc.

Tipping Point

Medline Plus

Full Text Available ... en español Blog About OnSafety CPSC Stands for Safety The Tipping Point Home > 60 Seconds of Safety (Videos) > The Tipping Point The Tipping Point by ... danger death electrical fall furniture head injury product safety television tipover tv Watch the video in Adobe ...

Analytic solution of the lifeguard problem

Science.gov (United States)

De Luca, Roberto; Di Mauro, Marco; Naddeo, Adele

2018-03-01

A simple version due to Feynman of Fermat’s principle is analyzed. It deals with the path a lifeguard on a beach must follow to reach a drowning swimmer. The solution for the exact point, P(x, 0) , at the beach-sea boundary, corresponding to the fastest path to the swimmer, is worked out in detail and the analogy with light traveling at the air-water boundary is described. The results agree with the known conclusion that the shortest path does not coincide with the fastest one. The relevance of the subject for a basic physics course, at an advanced high school level, is pointed out.

The geometry of percolation fronts in two-dimensional lattices with spatially varying densities

International Nuclear Information System (INIS)

Gastner, Michael T; Oborny, Beáta

2012-01-01

Percolation theory is usually applied to lattices with a uniform probability p that a site is occupied or that a bond is closed. The more general case, where p is a function of the position x, has received less attention. Previous studies with long-range spatial variations in p(x) have only investigated cases where p has a finite, non-zero gradient at the critical point p c . Here we extend the theory to two-dimensional cases in which the gradient can change from zero to infinity. We present scaling laws for the width and length of the hull (i.e. the boundary of the spanning cluster). We show that the scaling exponents for the width and the length depend on the shape of p(x), but they always have a constant ratio 4/3 so that the hull's fractal dimension D = 7/4 is invariant. On this basis, we derive and verify numerically an asymptotic expression for the probability h(x) that a site at a given distance x from p c is on the hull. (paper)

The oxidative stress and antioxidant responses of Litopenaeus vannamei to low temperature and air exposure.

Science.gov (United States)

Xu, Zihan; Regenstein, Joe M; Xie, Dandan; Lu, Wenjing; Ren, Xingchen; Yuan, Jiajia; Mao, Linchun

2018-01-01

Low temperature and air exposure were the key attributes for waterless transportation of fish and shrimp. In order to investigate the oxidative stress and antioxidant responses of the live shrimp Litopenaeus vannamei in the mimic waterless transportation, live shrimp were cooled at 13 °C for 3 min, stored in oxygen at 15 °C for 12 h, and then revived in water at 25 °C. The survival rate of shrimp under this waterless transportation system was over 86.67%. The ultrastructure of hepatopancreas cells were observed while activities of superoxide dismutase (SOD), peroxidase (POD), catalase (CAT), glutathione peroxidase (GSH-Px), antisuperoxide anion free radicals (ASAFR), total antioxidant capacity (TAOC), reactive oxygen species (ROS) production, content of malondialdehyde (MDA) and relative mRNA expressions of CAT and GSH-Px in the hemolymph and hepatopancreas were determined. Slight distortions of some organelles in hepatopancreas cells was reversible upon the shrimp revived from the cold shock. The activities of SOD, POD, CAT, GSH-Px, TAOC, ROS production and relative mRNA expressions of CAT and GSH-Px increased following the cold shock and reached peak levels after 3 or 6 h of storage, and then decreased gradually. There was no significant difference between the fresh and the revived shrimp in SOD, POD, GSH-Px, TAOC, ROS, MDA and relative mRNA expressions of CAT and GSH-Px. The oxidative stress and antioxidant responses were tissue-specific because hepatopancreas seemed to have a greater ability to defend against organelle damage and was more sensitive to stress than hemolymph based on the results of SOD activity, MDA content and GSH-Px mRNA expression. These results revealed that low temperature and air exposure caused significant oxidative and antioxidant responses, but did not lead to irreversible damages in this waterless system. Copyright © 2017 Elsevier Ltd. All rights reserved.

Ethyl cellulose nanoparticles as a platform to decrease ulcerogenic potential of piroxicam: formulation and in vitro/in vivo evaluation.

Science.gov (United States)

El-Habashy, Salma E; Allam, Ahmed N; El-Kamel, Amal H

2016-01-01

Nanoparticles (NPs) have long gained significant interest for their use in various drug formulations in order to increase bioavailability, prolong drug release, and decrease side effects of highly toxic drugs. The objective of this investigation was to evaluate the potential of ethyl cellulose-based NPs (EC-NPs) to modulate the release and reduce ulcerogenicity of piroxicam (PX) after oral administration. PX-loaded EC-NPs were prepared by solvent evaporation technique using different stabilizers at three concentration levels. Morphological examination of selected formulas confirmed the formation of spherical NPs with slightly porous surface. Formulation containing poloxamer-stabilized EC-NPs (P188/0.2), having a particle size of 240.26±29.24 nm, polydispersity index of 0.562±0.030, entrapment efficiency of 85.29%±1.57%, and modulated release of PX (88% after 12 hours), was selected as the optimum formulation. Differential scanning calorimetry demonstrated the presence of PX in an amorphous form in the NPs. Fourier-transform infrared spectroscopy revealed the possible formation of hydrogen bond and the absence of chemical interaction. In vivo study, evaluation of pharmacokinetic parameters, evaluation of gastric irritation potential, and histological examination were conducted after administration of the selected formulation. Time to reach maximum plasma concentration, t max, of poloxamer-stabilized EC-NPs was significantly higher than that of Feldene(®) 20 mg capsules (P≤0.001). Encapsulation of the acidic, gastric offender PX into NPs managed to significantly suppress gastric ulceration potential in rats (P≤0.05) as compared to that of PX suspension. A reduction of 66% in mean ulcer index was observed. In conclusion, poloxamer-stabilized EC-NPs (P188/0.2) had a significant potential of offsetting deleterious side effects common in PX use.

Sensitive and selective spectrophotometric assay of piroxicam in pure form, capsule and human blood serum samples via ion-pair complex formation

Science.gov (United States)

Alizadeh, Nina; Keyhanian, Fereshteh

2014-09-01

A simple, accurate and highly sensitive spectrophotometric method has been developed for the rapid determination of piroxicam (PX) in pure and pharmaceutical formulations. The proposed method involves formation of stable yellow colored ion-pair complexes of the amino derivative (basic nitrogen) of PX with three sulphonphthalein acid dyes namely; bromocresol green (BCG), bromothymol blue (BTB), bromophenol blue (BPB) in acidic medium. The colored species exhibited absorption maxima at 438, 429 and 432 nm with molar absorptivity values of 9.400 × 103, 1.218 × 103 and 1.02 × 104 L mol-1 cm-1 for PX-BCG, PX-BTB and PX-BPB complexes, respectively. The effect of optimum conditions via acidity, reagent concentration, time and solvent were studied. The reactions were extremely rapid at room temperature and the absorbance values remained constant for 48 h. Beer’s law was obeyed with a good correlation coefficient in the concentration ranges 1-100 μg mL-1 for BCG, BTB complexes and 1-95 μg mL-1 for BPB complex. The composition ratio of the ion-pair complexes were found to be 1:1 in all cases as established by Job’s method. No interference was observed from common additives and excipients which may be present in the pharmaceutical preparations. The proposed method was successfully applied for the determination of PX in capsule and human blood serum samples with good accuracy and precision.

Spider Veins

Science.gov (United States)

... and lead to blood pooling. Fall for bogus advertisements . While tempting, such treatments may not be legitimate. ... 480px View Render 320px View Connect with ASDS: Facebook LinkedIn YouTube Twitter Quick Links About ASDS Advocacy ...

Oxidative stress and antioxidant status in dairy cows during prepartal and postpartal periods

Directory of Open Access Journals (Sweden)

Jana Konvičná

2015-01-01

Full Text Available The aim of the present study was to evaluate the indicators of oxidative stress (malondialdehyde [MDA] and antioxidant status (ferric reducing ability of plasma [FRAP]; superoxide dismutase [SOD]; glutathione peroxidase [GSH-Px]; selenium [Se]; vitamin E in dairy cows of the Slovak Pied cattle from 3 weeks before parturition to 9 weeks after parturition. The mean MDA concentration was significantly (P P P P < 0.05 were recorded between Se and vitamin E (r = 0.897, SOD and GSH-Px (r = 0.903, while Se and GSH-Px had no significantly positive correlation (r = 0.520. Significant changes between MDA and indicators of oxidative stress (SOD, GSH-Px, vitamin E confirm that during parturition and onset of lactation, oxidative stress occurs in dairy cows. Exposure of peripartal cows to oxidative stress may cause an increased incidence of metabolic diseases.

Tyrosine phosphorylation of WW proteins

Science.gov (United States)

Reuven, Nina; Shanzer, Matan

2015-01-01

A number of key regulatory proteins contain one or two copies of the WW domain known to mediate protein–protein interaction via proline-rich motifs, such as PPxY. The Hippo pathway components take advantage of this module to transduce tumor suppressor signaling. It is becoming evident that tyrosine phosphorylation is a critical regulator of the WW proteins. Here, we review the current knowledge on the involved tyrosine kinases and their roles in regulating the WW proteins. PMID:25627656

Point-to-point people with purpose—Exploring the possibility of a commercial traveler market for point-to-point suborbital space transportation

Science.gov (United States)

Webber, Derek

2013-12-01

An argument was made at the First Arcachon Conference on Private Human Access to Space in 2008 [1] that some systematic market research should be conducted into potential market segments for point-to-point suborbital space transportation (PtP), in order to understand whether a commercial market exists which might augment possible government use for such a vehicle. The cargo market potential was subsequently addressed via desk research, and the results, which resulted in a pessimistic business case outlook, were presented in [2]. The same desk research approach is now used in this paper to address the potential business and wealthy individual passenger traveler market segment ("point-to-point people with purpose"). The results, with the assumed ticket pricing, are not encouraging.

Asymptotic behaviour of Feynman integrals

International Nuclear Information System (INIS)

Bergere, M.C.

1980-01-01

In these lecture notes, we describe how to obtain the asymptotic behaviour of Feynman amplitudes; this technique has been already applied in several cases, but the general solution for any kind of asymptotic behaviour has not yet been found. From the mathematical point of view, the problem to solve is close to the following problem: find the asymptotic expansion at large lambda of the integral ∫...∫ [dx] esup(-LambdaP[x]) where P[x] is a polynomial of several variables. (orig.)

Actividad de glutatión peroxidasa en bovinos lecheros a pastoreo correlacionada con la concentración sanguinea y plasmática de selenio Blood activity of glutathione peroxidase and its correlation with blood selenium concentration in grazing dairy cattle

Directory of Open Access Journals (Sweden)

Alejandro Ceballos

1999-12-01

Full Text Available Con el objeto de validar una técnica para determinar la actividad sanguínea de glutatión peroxidasa (GSH-Px; EC 1.11.1.9 en el Laboratorio de Patología Clínica de la Universidad Austral de Chile y establecer la correlación entre su actividad y la concentración sanguínea y plasmática de selenio (Se en bovinos a pastoreo en rebaños lecheros del sur de Chile, se tomaron 5-10 mL de sangre heparinizada a 112 vacas de ocho rebaños en la provincia de Valdivia. La actividad enzimática se analizó mediante una técnica cinética, y el Se por activación de neutrones. Fueron calculadas la inexactitud e imprecisión de la técnica cinética y se describen el rango, promedio y desviación estándar de la actividad enzimática. La correlación entre la actividad sanguínea de GSH-Px y la concentración de Se fue obtenida mediante el coeficiente de correlación simple. La inexactitud e imprecisión fueron 5,9% y 10%, respectivamente. La actividad de GSH-Px fue 89 ± 45 U/g de hemoglobina (Hb y la correlación entre las variables señaladas fue r=0,97 (PSelenium (Se is part of the antioxidant enzyme glutathione peroxidase (GSH-Px; EC 1.11.1.9 structure, whose blood activity is related to the blood level of selenium. This study was designed to validate the analytical method to analyze the GSH-Px blood activity at the Clinical Pathology Laboratory of the Universidad Austral de Chile, and to correlate it with blood Se level in dairy cattle from the South of Chile. Blood heparinized samples were taken from 112 dairy cows from eight dairy herds located at Valdivia province, Chile. A kinetic NADPH-dependent technique was used to analyze the blood GSH-Px, and the content of Se in blood and plasma was analyzed by neutron activation. The Se concentration in blood was analyzed in 12 samples to correlate GSH-Px blood activity with blood and plasma Se level. The inaccuracy and imprecision were 5.9% and 10%, respectively. The mean and standard deviation of the

Hardware-accelerated Point Generation and Rendering of Point-based Impostors

DEFF Research Database (Denmark)

Bærentzen, Jakob Andreas

2005-01-01

This paper presents a novel scheme for generating points from triangle models. The method is fast and lends itself well to implementation using graphics hardware. The triangle to point conversion is done by rendering the models, and the rendering may be performed procedurally or by a black box API....... I describe the technique in detail and discuss how the generated point sets can easily be used as impostors for the original triangle models used to create the points. Since the points reside solely in GPU memory, these impostors are fairly efficient. Source code is available online....

Progress of the Civil Engineering Work in the Main Amphithéâtre.

CERN Multimedia

Maximilien Brice

2011-01-01

Picture 1 and 2 : 31 Janvier 2011. - PanoA1 & PanoA2 : 09 March 2011. #mypanoviewer { height:480px; width: 800px; margin:auto} var viewer=new PTGuiViewer(); viewer.setSwfUrl("/record/1334834/files/PTGuiViewer.swf"); viewer.preferFlashViewer(); viewer.setVars({ pano: "/record/1334834/files/PanoA1_", format: "14faces", pan: 0, minpan: -180, maxpan: 180, tilt:0, mintilt: -75.60468140442133, maxtilt: 75.60468140442133, fov: 90, minfov: 10, maxfov: 120, autorotatespeed: 5, autorotatedelay: 10, maxiosdimension: 396 }); viewer.embed("mypanoviewer"); #mypanoviewer2 { height:480px; width: 800px; margin:auto} var viewer2=new PTGuiViewer(); viewer2.setSwfUrl("/record/1334834/files/PTGuiViewer.swf"); viewer2.preferFlashViewer(); viewer2.setVars({ pano: "/record/1334834/files/PanoA2_", format: "14faces", pan: 0, minpan: -180, maxpan: 180, tilt:0, mintilt: -75.60468140442133, maxtilt: 75.604681404...

Using Python to Program LEGO MINDSTORMS® Robots: The PyNXC Project

Directory of Open Access Journals (Sweden)

2010-04-01

Full Text Available

px/normal Helvetica; margin: 0px">px" class="Apple-style-span">

 

Determination of Optimal Double Sampling Plan using Genetic Algorithm

Directory of Open Access Journals (Sweden)

Sampath Sundaram

2012-03-01

Full Text Available Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4 Designing double sampling plan requires identification of sample sizes and acceptance numbers. In this paper a genetic algorithm has been designed for the selection of optimal acceptance numbers and sample sizes for the specified producer’s risk and consumer’s risk. Implementation of the algorithm has been illustrated numerically for different choices of quantities involved in a double sampling plan   

Laser Dew-Point Hygrometer

Science.gov (United States)

Matsumoto, Shigeaki; Toyooka, Satoru

1995-01-01

A rough-surface-type automatic dew-point hygrometer was developed using a laser diode and an optical fiber cable. A gold plate with 0.8 µ m average surface roughness was used as a surface for deposition of dew to facilitate dew deposition and prevent supersaturation of water vapor at the dew point. It was shown experimentally that the quantity of dew deposited can be controlled to be constant at any predetermined level, and is independent of the dew point to be measured. The dew points were measured in the range from -15° C to 54° C in which the temperature ranged from 0° C to 60° C. The measurement error of the dew point was ±0.5° C which was equal to below ±2% in relative humidity in the above dew-point range.

Construyendo soportes para el cuidado: producción de discursos de profesores sobre inclusión de niños y adolescentes con deficiencia Building scaffolding for care: Teachers' discourse and the inclusion of children and adolescents with impairments Construindo suportes para o cuidado: produção de discursos de professores sobre a inclusão de crianças e adolescentes com deficiência

Directory of Open Access Journals (Sweden)

Paulo Franca

2009-05-01

Full Text Available

px; color: #333333;">px; font-family: Times; color: #000000;">

Measurement of polarization-transfer to bound protons in carbon and its virtuality dependence

Science.gov (United States)

Izraeli, D.; Brecelj, T.; Achenbach, P.; Ashkenazi, A.; Böhm, R.; Cohen, E. O.; Distler, M. O.; Esser, A.; Gilman, R.; Kolar, T.; Korover, I.; Lichtenstadt, J.; Mardor, I.; Merkel, H.; Mihovilovič, M.; Müller, U.; Olivenboim, M.; Piasetzky, E.; Ron, G.; Schlimme, B. S.; Schoth, M.; Sfienti, C.; Širca, S.; Štajner, S.; Strauch, S.; Thiel, M.; Weber, A.; Yaron, I.; A1 Collaboration

2018-06-01

We measured the ratio Px /Pz of the transverse to longitudinal components of polarization transferred from electrons to bound protons in 12C by the 12C (e → ,e‧ p →) process at the Mainz Microtron (MAMI). We observed consistent deviations from unity of this ratio normalized to the free-proton ratio, (Px /Pz) 12C /(Px /Pz) 1H, for both s- and p-shell knocked out protons, even though they are embedded in averaged local densities that differ by about a factor of two. The dependence of the double ratio on proton virtuality is similar to the one for knocked out protons from 2H and 4He, suggesting a universal behavior. It further implies no dependence on average local nuclear density.

Learning power point 2000 easily

Energy Technology Data Exchange (ETDEWEB)

Mon, In Su; Je, Jung Suk

2000-05-15

This book introduces power point 2000, which gives descriptions what power point is, what we can do with power point 2000, is it possible to install power point 2000 in my computer? Let's run power point, basic of power point such as new presentation, writing letter, using text box, changing font size, color and shape, catching power user, insertion of word art and creating of new file. It also deals with figure, chart, graph, making multimedia file, presentation, know-how of power point for teachers and company workers.

From Contrapuntal Music to Polyphonic Novel: Aldous Huxley’s Point Counter Point

Directory of Open Access Journals (Sweden)

Mevlüde ZENGİN

2015-06-01

Full Text Available Taken at face value Point Counter Point (1928 written by Aldous Huxley seems to be a novel including many stories of various and sundry people and reflecting their points of view about the world in which they live and about the life they have been leading. However, it is this very quality of the novel that provides grounds for the study of the novel as a polyphonic one. The novel presents to its reader an aggregate of strikingly different characters and thus a broad spectrum of contemporary society. The characters in the novel are all characterized by and individualized with easily recognizable physical, intellectual, emotional, psychological and moral qualities. Each of them is well-contrived through their differences in social status, political views, wealth, etc. Thus, many different viewpoints, conflicting voices, contrasting insights and ideas are heard and seen synchronically in Point Counter Point, which makes it polyphonic. Polyphony is a musical motif referring to different notes and chords played at the same time to create a rhythm. It was first adopted by M. M. Bakhtin to analyze F. M. Dostoyevsky’s fiction. The aim of this study is firstly to elucidate, in Bakhtinian thought, polyphony and then dialogism and heteroglossia closely related to his concept of polyphony; and then to put the polyphonic qualities in Point Counter Point forth, studying the novel’s dialogism and heteroglot qualities

Flow area optimization in point to area or area to point flows

International Nuclear Information System (INIS)

Ghodoossi, Lotfollah; Egrican, Niluefer

2003-01-01

This paper deals with the constructal theory of generation of shape and structure in flow systems connecting one point to a finite size area. The flow direction may be either from the point to the area or the area to the point. The formulation of the problem remains the same if the flow direction is reversed. Two models are used in optimization of the point to area or area to point flow problem: cost minimization and revenue maximization. The cost minimization model enables one to predict the shape of the optimized flow areas, but the geometric sizes of the flow areas are not predictable. That is, as an example, if the area of flow is a rectangle with a fixed area size, optimization of the point to area or area to point flow problem by using the cost minimization model will only predict the height/length ratio of the rectangle not the height and length itself. By using the revenue maximization model in optimization of the flow problems, all optimized geometric aspects of the interested flow areas will be derived as well. The aim of this paper is to optimize the point to area or area to point flow problems in various elemental flow area shapes and various structures of the flow system (various combinations of elemental flow areas) by using the revenue maximization model. The elemental flow area shapes used in this paper are either rectangular or triangular. The forms of the flow area structure, made up of an assembly of optimized elemental flow areas to obtain bigger flow areas, are rectangle-in-rectangle, rectangle-in-triangle, triangle-in-triangle and triangle-in-rectangle. The global maximum revenue, revenue collected per unit flow area and the shape and sizes of each flow area structure have been derived in optimized conditions. The results for each flow area structure have been compared with the results of the other structures to determine the structure that provides better performance. The conclusion is that the rectangle-in-triangle flow area structure

Professional SharePoint 2010 Development

CERN Document Server

Rizzo, Tom; Fried, Jeff

2010-01-01

Learn to leverage the features of the newest version of SharePoint, in this update to the bestseller. More than simply a portal, SharePoint is Microsoft's popular content management solution for building intranets and Web sites or hosting wikis and blogs. Offering broad coverage on all aspects of development for the SharePoint platform, this comprehensive book shows you exactly what SharePoint does, how to build solutions, and what features are accessible within SharePoint. Written by one of the most recognized names in SharePoint development, Professional SharePoint 2010 Development offers an

The Lagrangian Points

Science.gov (United States)

Linton, J. Oliver

2017-01-01

There are five unique points in a star/planet system where a satellite can be placed whose orbital period is equal to that of the planet. Simple methods for calculating the positions of these points, or at least justifying their existence, are developed.

The End of Points

Science.gov (United States)

Feldman, Jo

2018-01-01

Have teachers become too dependent on points? This article explores educators' dependency on their points systems, and the ways that points can distract teachers from really analyzing students' capabilities and achievements. Feldman argues that using a more subjective grading system can help illuminate crucial information about students and what…

Multispectral Image Feature Points

Directory of Open Access Journals (Sweden)

Cristhian Aguilera

2012-09-01

Full Text Available This paper presents a novel feature point descriptor for the multispectral image case: Far-Infrared and Visible Spectrum images. It allows matching interest points on images of the same scene but acquired in different spectral bands. Initially, points of interest are detected on both images through a SIFT-like based scale space representation. Then, these points are characterized using an Edge Oriented Histogram (EOH descriptor. Finally, points of interest from multispectral images are matched by finding nearest couples using the information from the descriptor. The provided experimental results and comparisons with similar methods show both the validity of the proposed approach as well as the improvements it offers with respect to the current state-of-the-art.

Quantitative structure-property relationships for prediction of boiling point, vapor pressure, and melting point.

Science.gov (United States)

Dearden, John C

2003-08-01

Boiling point, vapor pressure, and melting point are important physicochemical properties in the modeling of the distribution and fate of chemicals in the environment. However, such data often are not available, and therefore must be estimated. Over the years, many attempts have been made to calculate boiling points, vapor pressures, and melting points by using quantitative structure-property relationships, and this review examines and discusses the work published in this area, and concentrates particularly on recent studies. A number of software programs are commercially available for the calculation of boiling point, vapor pressure, and melting point, and these have been tested for their predictive ability with a test set of 100 organic chemicals.

The correspondence of Giovanni Santini and Giuseppe Lorenzoni, directors of the Astronomical Observatory of Padua in the 19th century

Directory of Open Access Journals (Sweden)

Luisa Pigatto

2009-06-01

Full Text Available

px 0.0px 0.0px 0.0px; font: 9.0px Times;">Giovanni Santini was appointed director of the Astronomical Observatory of Padova from 1817 to 1877. His scientific correspondence covers a period from 1807 to 1874. Most of the letters are from Italian and European astronomers, mainly concerning astronomical subjects. In actual fact, all Santini’s activity was devoted to the classical astronomy, mainly to the new comets and planets orbit calculation, as far as to the compilation of a catalogue of almost ten thousand stars. From 1821 to 1828, he was involved in geodetic observations in order to determine the difference of longitude between Milan-Padua and Padua-Fiume. Giuseppe Lorenzoni was appointed director after Santini’s death, from 1877 to 1913. Since 1873, he took part in the Italian Geodetic Commission to which he devoted almost all his scientific activity. Lorenzoni’s scientific correspondence was partly lost for war reasons. A partial correspondence with Giovanni Virginio Schiaparelli and almost the complete correspondence with Pietro Tacchini, were recovered after the second World War. Santini and Lorenzoni correspondence cover a period about a hundred years long. So, it is an important tool of knowledge for the history of Padova Astronomical Observatory in the 19th century, for its scientific activity, and for the relationship among Italian and European astronomers and institutions.

Professional SharePoint 2010 Development

CERN Document Server

Rizzo, Tom; Fried, Jeff; Swider, Paul J; Hillier, Scot; Schaefer, Kenneth

2012-01-01

Updated guidance on how to take advantage of the newest features of SharePoint programmability More than simply a portal, SharePoint is Microsoft's popular content management solution for building intranets and websites or hosting wikis and blogs. Offering broad coverage on all aspects of development for the SharePoint platform, this comprehensive book shows you exactly what SharePoint does, how to build solutions, and what features are accessible within SharePoint. Written by a team of SharePoint experts, this new edition offers an extensive selection of field-tested best practices that shows

SharePoint 2010 For Dummies

CERN Document Server

Williams, Vanessa L

2012-01-01

Here's the bestselling guide on SharePoint 2010, updated to cover Office 365 SharePoint Portal Server is an essential part of the enterprise infrastructure for many businesses. The Office 365 version includes significantly enhanced cloud capabilities. This second edition of the bestselling guide to SharePoint covers getting a SharePoint site up and running, branded, populated with content, and more. It explains ongoing site management and offers plenty of advice for administrators who want to leverage SharePoint and Office 365 in various ways.Many businesses today rely on SharePoint Portal Ser

Impaired insulin-stimulated nonoxidative glucose metabolism in pancreas-kidney transplant recipients

DEFF Research Database (Denmark)

Christiansen, Erik; Vestergaard, Henrik; Tibell, Annika

1996-01-01

-response curve for glucose disposal rates (Rd) was shifted to the right in the Px and Kx groups, and the maximal glucose disposal rate was reduced by 40% in the Px group (11.7 +/- 1.1 mg.kg-1 fat-free mass.min-1) and 30% in the Kx group (13.9 +/- 1.2 mg.kg-1 fat-free mass.min-1) compared with that in control...

ON A NUMERICAL ALGORITHM FOR UNCERTAIN SYSTEM ∫ Φ ...

African Journals Online (AJOL)

Administrator

Science World Journal Vol 7 (No 1) 2012 www.scienceworldjournal.org. ISSN 1597-6343. On a Numerical Algorithm for Uncertain System. Newton's Algorithm. Step 1 Calculate. )(),().(k k k. xAxgxF. Step 2. Check if ε. <. )(k xg for a predetermined ,ε if so stop, else. Step3. Set k k. PxA. )( = )(k xg. -. Step4. Set k k k. Px x. +. = +1.

Impaired insulin-stimulated nonoxidative glucose metabolism in pancreas-kidney transplant recipients. Dose-response effects of insulin on glucose turnover

DEFF Research Database (Denmark)

Christiansen, E; Vestergaard, H; Tibell, A

1996-01-01

-response curve for glucose disposal rates (Rd) was shifted to the right in the Px and Kx groups, and the maximal glucose disposal rate was reduced by 40% in the Px group (11.7 +/- 1.1 mg.kg-1 fat-free mass.min-1) and 30% in the Kx group (13.9 +/- 1.2 mg.kg-1 fat-free mass.min-1) compared with that in control...

Throughput analysis of point-to-multi-point hybric FSO/RF network

KAUST Repository

Rakia, Tamer; Gebali, Fayez; Yang, Hong-Chuan; Alouini, Mohamed-Slim

2017-01-01

This paper presents and analyzes a point-to-multi-point (P2MP) network that uses a number of free-space optical (FSO) links for data transmission from the central node to the different remote nodes. A common backup radio-frequency (RF) link is used

Pilot points method for conditioning multiple-point statistical facies simulation on flow data

Science.gov (United States)

Ma, Wei; Jafarpour, Behnam

2018-05-01

We propose a new pilot points method for conditioning discrete multiple-point statistical (MPS) facies simulation on dynamic flow data. While conditioning MPS simulation on static hard data is straightforward, their calibration against nonlinear flow data is nontrivial. The proposed method generates conditional models from a conceptual model of geologic connectivity, known as a training image (TI), by strategically placing and estimating pilot points. To place pilot points, a score map is generated based on three sources of information: (i) the uncertainty in facies distribution, (ii) the model response sensitivity information, and (iii) the observed flow data. Once the pilot points are placed, the facies values at these points are inferred from production data and then are used, along with available hard data at well locations, to simulate a new set of conditional facies realizations. While facies estimation at the pilot points can be performed using different inversion algorithms, in this study the ensemble smoother (ES) is adopted to update permeability maps from production data, which are then used to statistically infer facies types at the pilot point locations. The developed method combines the information in the flow data and the TI by using the former to infer facies values at selected locations away from the wells and the latter to ensure consistent facies structure and connectivity where away from measurement locations. Several numerical experiments are used to evaluate the performance of the developed method and to discuss its important properties.

Digital microwave communication engineering point-to-point microwave systems

CERN Document Server

Kizer, George

2013-01-01

The first book to cover all engineering aspects of microwave communication path design for the digital age Fixed point-to-point microwave systems provide moderate-capacity digital transmission between well-defined locations. Most popular in situations where fiber optics or satellite communication is impractical, it is commonly used for cellular or PCS site interconnectivity where digital connectivity is needed but not economically available from other sources, and in private networks where reliability is most important. Until now, no book has adequately treated all en

Dynamic Fracture Initiation Toughness at Elevated Temperatures With Application to the New Generation of Titanium Aluminide Alloys. Chapter 8

Science.gov (United States)

Shazly, Mostafa; Prakash, Vikas; Draper, Susan; Shukla, Arun (Editor)

2006-01-01

Recently, a new generation of titanium aluminide alloy, named Gamma-Met PX, has been developed with better rolling and post-rolling characteristics. I'revious work on this alloy has shown the material to have higher strengths at room and elevated temperatures when compared with other gamma titanium aluminides. In particular, this new alloy has shown increased ductility at elevated temperatures under both quasi-static and high strain rate uniaxial compressive loading. However, its high strain rate tensile ductility at room and elevated temperatures is limited to approx. 1%. In the present chapter, results of a study to investigate the effects of loading rate and test temperature on the dynamic fracture initiation toughness in Gamma-Met PX are presented. Modified split Hopkinson pressure bar was used along with high-speed photography to determine the crack initiation time. Three-point bend dynamic fracture experiments were conducted at impact speeds of approx. 1 m/s and tests temperatures of up-to 1200 C. The results show that thc dynamic fracture initiation toughness decreases with increasing test temperatures beyond 600 C. Furthermore, thc effect of long time high temperature air exposure on the fracture toughness was investigated. The dynamic fracture initiation toughness was found to decrease with increasing exposure time. The reasons behind this drop are analyzed and discussed.

Late Wash/Nitric Acid flowsheet hydrogen generation bases for simulation of a deflagration/detonation in the DWPF CPC

International Nuclear Information System (INIS)

Ritter, J.A.

1993-01-01

Hydrogen generation data obtained from IDMS runs PX4 and PX5 will be used to determine a bases for a deflagration/detonation simulation in the DWPF CPC. This simulation is necessary due to the new chemistry associated with the Late Wash/ Nitric Acid flowsheet and process modifications associated with the presence of H 2 in the offgas. The simulation will be performed by Professor Van Brunt from the University of South Carolina. The scenario which leads up to the deflagration/detonation simulation will be chosen such that the following conditions apply. The SRAT is filled to its maximum operating level with 9,600 gal of sludge, which corresponds to the minimum vapor space above the sludge. The SRAT is at the boiling point, producing H 2 at a very low rate (about 10 % of the peak) and 15 scfm of air inleakage is entering the SRAT. Then, the H 2 generation rate will be allowed to increase exponentially (catalyst activation) until it readies the peak H 2 generation rate of the IDMS run, after which the H 2 generation rate will be allowed to decay exponentially (catalyst deactivation) until the total amount of H2 produced is between 85 and 100% of that produced during the IDMS run

The goal of ape pointing.

Science.gov (United States)

Halina, Marta; Liebal, Katja; Tomasello, Michael

2018-01-01

Captive great apes regularly use pointing gestures in their interactions with humans. However, the precise function of this gesture is unknown. One possibility is that apes use pointing primarily to direct attention (as in "please look at that"); another is that they point mainly as an action request (such as "can you give that to me?"). We investigated these two possibilities here by examining how the looking behavior of recipients affects pointing in chimpanzees (Pan troglodytes) and bonobos (Pan paniscus). Upon pointing to food, subjects were faced with a recipient who either looked at the indicated object (successful-look) or failed to look at the indicated object (failed-look). We predicted that, if apes point primarily to direct attention, subjects would spend more time pointing in the failed-look condition because the goal of their gesture had not been met. Alternatively, we expected that, if apes point primarily to request an object, subjects would not differ in their pointing behavior between the successful-look and failed-look conditions because these conditions differed only in the looking behavior of the recipient. We found that subjects did differ in their pointing behavior across the successful-look and failed-look conditions, but contrary to our prediction subjects spent more time pointing in the successful-look condition. These results suggest that apes are sensitive to the attentional states of gestural recipients, but their adjustments are aimed at multiple goals. We also found a greater number of individuals with a strong right-hand than left-hand preference for pointing.

Automatic markerless registration of point clouds with semantic-keypoint-based 4-points congruent sets

Science.gov (United States)

Ge, Xuming

2017-08-01

The coarse registration of point clouds from urban building scenes has become a key topic in applications of terrestrial laser scanning technology. Sampling-based algorithms in the random sample consensus (RANSAC) model have emerged as mainstream solutions to address coarse registration problems. In this paper, we propose a novel combined solution to automatically align two markerless point clouds from building scenes. Firstly, the method segments non-ground points from ground points. Secondly, the proposed method detects feature points from each cross section and then obtains semantic keypoints by connecting feature points with specific rules. Finally, the detected semantic keypoints from two point clouds act as inputs to a modified 4PCS algorithm. Examples are presented and the results compared with those of K-4PCS to demonstrate the main contributions of the proposed method, which are the extension of the original 4PCS to handle heavy datasets and the use of semantic keypoints to improve K-4PCS in relation to registration accuracy and computational efficiency.

Analisis de crecimiento de Limonium sinuatum Mill cv. Midnight Blue propagada sexual y asexualmente a partir de yemas vegetativas y florales.

Directory of Open Access Journals (Sweden)

Pedroza Jaime

1997-06-01

Full Text Available

px;">Se realizo el análisis clásico de crecimiento de plantas de estatice px;">(Limoniumpx;"> px;">sinuatum px;">Mill. cv. Midnight Blue propagadas sexualmente y mediante los sistemas px;">in vitro,px;"> a partir de yemas vegetativas y florales bajo condiciones de invernadero en la Sabana de Bogotá, Colombia, mediante el empleo de 10 índices que evalúan el desempeño fisiológico del material vegetal. En este cultivar es característico el comportamiento oscilatorio y simétrico de algunos índices que evidencian una posible actividad fisiológica muy particular en la relación Fuente: Demanda; Así, la exportaci6n de fotoasimilados (RAF esta afectada por su retención en las hojas (AFE, especialmente durante la fase vegetativa. De igual forma. es importante destacar que, en la fase reproductiva, los tallos florales son la principal demanda de fotosintatos. Con respecto a la T.R.C., se nota que detalla muy bien el crecimiento vegetativo y es afectada por la T.A.N., mientras que la T.C.C, el reproductivo.

Aunque se presentaron algunas diferencias cuantitativas en la fase vegetativa, en la reproductiva, presumiblemente, por efectos fisiológicos compensatorios, ocurre total homogeneidad entre los tipos de plantas analizadas.

Point Cluster Analysis Using a 3D Voronoi Diagram with Applications in Point Cloud Segmentation

Directory of Open Access Journals (Sweden)

Shen Ying

2015-08-01

Full Text Available Three-dimensional (3D point analysis and visualization is one of the most effective methods of point cluster detection and segmentation in geospatial datasets. However, serious scattering and clotting characteristics interfere with the visual detection of 3D point clusters. To overcome this problem, this study proposes the use of 3D Voronoi diagrams to analyze and visualize 3D points instead of the original data item. The proposed algorithm computes the cluster of 3D points by applying a set of 3D Voronoi cells to describe and quantify 3D points. The decompositions of point cloud of 3D models are guided by the 3D Voronoi cell parameters. The parameter values are mapped from the Voronoi cells to 3D points to show the spatial pattern and relationships; thus, a 3D point cluster pattern can be highlighted and easily recognized. To capture different cluster patterns, continuous progressive clusters and segmentations are tested. The 3D spatial relationship is shown to facilitate cluster detection. Furthermore, the generated segmentations of real 3D data cases are exploited to demonstrate the feasibility of our approach in detecting different spatial clusters for continuous point cloud segmentation.

SharePoint 2010 Field Guide

CERN Document Server

Mann, Steven; Gazmuri, Pablo; Caravajal, Steve; Wheeler, Christina

2012-01-01

Hands-on solutions for common SharePoint 2010 challenges Aimed at the more than 100 million licensed SharePoint 2010 users, this indispensable field guide addresses an abundance of common SharePoint 2010 problems and offers proven solutions. A team of authors encourages you to customize SharePoint beyond the out-of-the-box functionality so that you can build more complex solutions to these challenges. You?ll discover intricate details and specific full-scale solutions that you can then implement to your own SharePoint 2010 solutions.Tackles a variety of SharePoint 2010 problems ranging from si

Professional SharePoint 2010 Administration

CERN Document Server

Klindt, Todd; Caravajal, Steve

2010-01-01

Thorough coverage of the improvements and changes to SharePoint 2010. SharePoint 2010 boasts a variety of incredible new features that will challenge even the most experienced administrator who is upgrading from SharePoint 2007. Written by a team of SharePoint experts, this book places a takes aim at showing you how to make these new features work right for you. Offering an in-depth look at SharePoint 2010, the authors focus on how SharePoint functionality has changed from its earliest version to its newest, and they provide you with detailed coverage of all the new features and capabilities.:

Professional SharePoint 2013 administration

CERN Document Server

Young, Shane; Klindt, Todd

2013-01-01

SharePoint admin author gurus return to prepare you for working with the new features of SharePoint 2013! The new iteration of SharePoint boasts exciting new features. However, any new version also comes with its fair share of challenges and that's where this book comes in. The team of SharePoint admin gurus returns to presents a fully updated resource that prepares you for making all the new SharePoint 2013 features work right. They cover all of the administration components of SharePoint 2013 in detail, and present a clear understanding of how they affect the role of the adminis

High dimension feature extraction based visualized SOM fault diagnosis method and its application in p-xylene oxidation process☆

Institute of Scientific and Technical Information of China (English)

Ying Tian; Wenli Du; Feng Qian

2015-01-01

Purified terephthalic acid (PTA) is an important chemical raw material. P-xylene (PX) is transformed to terephthalic acid (TA) through oxidation process and TA is refined to produce PTA. The PX oxidation reaction is a complex process involving three-phase reaction of gas, liquid and solid. To monitor the process and to im-prove the product quality, as wel as to visualize the fault type clearly, a fault diagnosis method based on self-organizing map (SOM) and high dimensional feature extraction method, local tangent space alignment (LTSA), is proposed. In this method, LTSA can reduce the dimension and keep the topology information simultaneously, and SOM distinguishes various states on the output map. Monitoring results of PX oxidation reaction process in-dicate that the LTSA–SOM can wel detect and visualize the fault type.

I See Your Point: Infants under 12 Months Understand that Pointing Is Communicative

Science.gov (United States)

Krehm, Madelaine; Onishi, Kristine H.; Vouloumanos, Athena

2014-01-01

Do young infants understand that pointing gestures allow the pointer to change the information state of a recipient? We used a third-party experimental scenario to examine whether 9- and 11-month-olds understand that a pointer's pointing gesture can inform a recipient about a target object. When the pointer pointed to a target, infants…

Bubble-point and dew-point equation for binary refrigerant mixture R22-R142b

Energy Technology Data Exchange (ETDEWEB)

Liancheng Tan; Zhongyou Zhao; Yonghong Duan (Xi' an Jiaotong Univ., Xi' an (China). Dept. of Power Machinery Engineering)

1992-01-01

A bubble-point and dew-point equation (in terms either of temperature or of pressure is suggested for the refrigerant mixture R22-R142b), which is regarded as one of the alternatives to R12. This equation has been examined with experimental data. A modified Rackett equation for the calculation of the bubble-point volume is also proposed. Compared with the experimental data, the rms errors in the calculated values of the bubble-point temperature, the dew-point temperature, and the bubble-point volume are 1.093%, 0.947%, and 1.120%, respectively. The calculation covers a wide range of temperatures and pressures, even near the critical point. It is shown how the equations are extrapolated to calculate other binary refrigerant mixtures. (author)

Imaging study on acupuncture points

Science.gov (United States)

Yan, X. H.; Zhang, X. Y.; Liu, C. L.; Dang, R. S.; Ando, M.; Sugiyama, H.; Chen, H. S.; Ding, G. H.

2009-09-01

The topographic structures of acupuncture points were investigated by using the synchrotron radiation based Dark Field Image (DFI) method. Four following acupuncture points were studied: Sanyinjiao, Neiguan, Zusanli and Tianshu. We have found that at acupuncture point regions there exists the accumulation of micro-vessels. The images taken in the surrounding tissue out of the acupuncture points do not show such kind of structure. It is the first time to reveal directly the specific structure of acupuncture points by X-ray imaging.

Imaging study on acupuncture points

International Nuclear Information System (INIS)

Yan, X H; Zhang, X Y; Liu, C L; Dang, R S; Ando, M; Sugiyama, H; Chen, H S; Ding, G H

2009-01-01

The topographic structures of acupuncture points were investigated by using the synchrotron radiation based Dark Field Image (DFI) method. Four following acupuncture points were studied: Sanyinjiao, Neiguan, Zusanli and Tianshu. We have found that at acupuncture point regions there exists the accumulation of micro-vessels. The images taken in the surrounding tissue out of the acupuncture points do not show such kind of structure. It is the first time to reveal directly the specific structure of acupuncture points by X-ray imaging.

Magic Pointing for Eyewear Computers

DEFF Research Database (Denmark)

Jalaliniya, Shahram; Mardanbegi, Diako; Pederson, Thomas

2015-01-01

In this paper, we propose a combination of head and eye movements for touchlessly controlling the "mouse pointer" on eyewear devices, exploiting the speed of eye pointing and accuracy of head pointing. The method is a wearable computer-targeted variation of the original MAGIC pointing approach...... which combined gaze tracking with a classical mouse device. The result of our experiment shows that the combination of eye and head movements is faster than head pointing for far targets and more accurate than eye pointing....

Adaptive Soft-sensor Modeling Algorithm Based on FCMISVM and Its Application in PX Adsorption Separation Process%基于FCMISVM的自适应软测量建模算法及其在PX吸附分离过程中的应用

Institute of Scientific and Technical Information of China (English)

傅永峰; 苏宏业; 张英; 褚健

2008-01-01

To overcome the problem that soft sensor models cannot be updated with the process changes.a soft sensor modeling algorithm based on hybrid fuzzy C-means(FCM、algorithm and incremental support vector ma-chines(ISVM)iS proposed.This hybrid algorithm FCMISVM includes three parts:samples clustering based on FCM algorithm.leaming algorithm based on ISVM.and heuristic sample displacement method.In the training process,the training samples are first clustered bv the FCM algorithm.and then by training each clustering with the sVM algorithm.a sub-model is built to each clustering.In the predicting process.when an incremental sample that represents new operation information is introduced in the model,the fuzzy membership function of the sample to each clustering is first computed bv the FCM algorithm.Then.a corresponding SVM sub.model of the clustering with the largest fuzzy membership function iS used to predict and perform incremental learning SO the model can be updated on-line.An old sample chosen by heuristic sample displacement method iS then discarded from the sub-model to control the size of the working set.The proposed method is applied to predict the P-xylene(PX)purity in the adsorption separation process.Simulation results indicate that the proposed method actually increases the model'S adaptive abilities to various operation conditions and improves its generalization capability.

View of the Linac 4 building under construction.

CERN Multimedia

Sousa Mickael

2011-01-01

#mypanoviewer { height:480px; width: 800px; margin:auto} var viewer=new PTGuiViewer(); viewer.setSwfUrl("/record/1341296/files/PTGuiViewer.swf"); viewer.preferFlashViewer(); viewer.setVars({ pano: "/record/1341296/files/pano04_", format: "14faces", pan: 0, minpan: -180, maxpan: 180, tilt:0, mintilt: -75.60468140442133, maxtilt: 75.60468140442133, fov: 90, minfov: 10, maxfov: 120, autorotatespeed: 5, autorotatedelay: 10, maxiosdimension: 396 }); viewer.embed("mypanoviewer");

Effect of saddle-point anisotropy on point-defect drift-diffusion into straight dislocations

International Nuclear Information System (INIS)

Skinner, B.C.; Woo, C.H.

1983-02-01

Effects on point-defect drift-diffusion in the strain fields of edge or screw dislocations, due to the anisotropy of the point defect in its saddle-point configuration, are investigated. Expressions for sink strength and bias that include the saddle-point shape effect are derived, both in the absence and presence of an externally applied stress. These are found to depend on intrinsic parameters such as the relaxation volume and the saddle-point shape of the point defects, and extrinsic parameters such as temperature and the magnitude and direction of the externally applied stress with respect to the line direction and Burgers vector direction of the dislocation. The theory is applied to fcc copper and bcc iron. It is found that screw dislocations are biased sinks and that the stress-induced bias differential for the edge dislocations depends much more on the line direction than the Burgers vector direction. Comparison with the stress-induced bias differential due to the usual SIPA effect is made. It is found that the present effect causes a bias differential that is more than an order of magnitude larger

Handbook of floating-point arithmetic

CERN Document Server

Muller, Jean-Michel; de Dinechin, Florent; Jeannerod, Claude-Pierre; Joldes, Mioara; Lefèvre, Vincent; Melquiond, Guillaume; Revol, Nathalie; Torres, Serge

2018-01-01

This handbook is a definitive guide to the effective use of modern floating-point arithmetic, which has considerably evolved, from the frequently inconsistent floating-point number systems of early computing to the recent IEEE 754-2008 standard. Most of computational mathematics depends on floating-point numbers, and understanding their various implementations will allow readers to develop programs specifically tailored for the standard’s technical features. Algorithms for floating-point arithmetic are presented throughout the book and illustrated where possible by example programs which show how these techniques appear in actual coding and design. The volume itself breaks its core topic into four parts: the basic concepts and history of floating-point arithmetic; methods of analyzing floating-point algorithms and optimizing them; implementations of IEEE 754-2008 in hardware and software; and useful extensions to the standard floating-point system, such as interval arithmetic, double- and triple-word arithm...

Indexing Moving Points

DEFF Research Database (Denmark)

Agarwal, Pankaj K.; Arge, Lars Allan; Erickson, Jeff

2003-01-01

We propose three indexing schemes for storing a set S of N points in the plane, each moving along a linear trajectory, so that any query of the following form can be answered quickly: Given a rectangle R and a real value t, report all K points of S that lie inside R at time t. We first present an...

Inhibition effect of calcium hydroxide point and chlorhexidine point on root canal bacteria of necrosis teeth

Directory of Open Access Journals (Sweden)

Andry Leonard Je

2006-03-01

Full Text Available Calcium Hydroxide point and Chlorhexidine point are new drugs for eliminating bacteria in the root canal. The points slowly and controly realease Calcium Hydroxide and Chlorhexidine into root canal. The purpose of the study was to determined the effectivity of Calcium hydroxide point (Calcium hydroxide plus point and Chlorhexidine point in eleminating the root canal bacteria of nescrosis teeth. In this study 14 subjects were divided into 2 groups. The first group was treated with Calcium hydroxide point and the second was treated with Chlorhexidine poin. The bacteriological sampling were measured with spectrofotometry. The Paired T Test analysis (before and after showed significant difference between the first and second group. The Independent T Test which analysed the effectivity of both groups had not showed significant difference. Although there was no significant difference in statistical test, the result of second group eliminate more bacteria than the first group. The present finding indicated that the use of Chlorhexidine point was better than Calcium hydroxide point in seven days period. The conclusion is Chlorhexidine point and Calcium hydroxide point as root canal medicament effectively eliminate root canal bacteria of necrosis teeth.

Pro SharePoint 2013 administration

CERN Document Server

Garrett, Robert

2013-01-01

Pro SharePoint 2013 Administration is a practical guide to SharePoint 2013 for intermediate to advanced SharePoint administrators and power users, covering the out-of-the-box feature set and capabilities of Microsoft's collaboration and business productivity platform. SharePoint 2013 is an incredibly complex product, with many moving parts, new features, best practices, and 'gotchas.' Author Rob Garrett distills SharePoint's portfolio of features, capabilities, and utilities into an in-depth professional guide-with no fluff and copious advice-that is designed from scratch to be the manual Micr

Geodetic Control Points - Multi-State Control Point Database

Data.gov (United States)

NSGIC State | GIS Inventory — The Multi-State Control Point Database (MCPD) is a database of geodetic and mapping control covering Idaho and Montana. The control were submitted by registered land...

Modelling point patterns with linear structures

DEFF Research Database (Denmark)

Møller, Jesper; Rasmussen, Jakob Gulddahl

2009-01-01

processes whose realizations contain such linear structures. Such a point process is constructed sequentially by placing one point at a time. The points are placed in such a way that new points are often placed close to previously placed points, and the points form roughly line shaped structures. We...... consider simulations of this model and compare with real data....

Modelling point patterns with linear structures

DEFF Research Database (Denmark)

Møller, Jesper; Rasmussen, Jakob Gulddahl

processes whose realizations contain such linear structures. Such a point process is constructed sequentially by placing one point at a time. The points are placed in such a way that new points are often placed close to previously placed points, and the points form roughly line shaped structures. We...... consider simulations of this model and compare with real data....

Selenium Status in Heifers, Late Pregnancy Cows and Their Calves in the Šumava Region, Czech Republic

Directory of Open Access Journals (Sweden)

P. Slavík

2007-01-01

Full Text Available The objective of this study was to ascertain selenium status in beef cattle in different stages of production in the Šumava region. In the region, blood collections and analyses for selected metabolic variables were performed in 54 animals in different production stages (18 heifers, 18 cows in late pregnancy and 18 calves aged 3 weeks on the average. Three herds were studied. The selenium status was determined both directly by measuring serum selenium (Se contents and indirectly by measuring glutathione peroxidase (GSH-Px activity in whole blood. The mean serum selenium concentration in all the animals under study (n = 54 was 30.6 μg/l +/- 2.91, and mean GSH-Px activity was 167.01 μkat/l +/- 92.39. In heifers, mean serum selenium concentration was 34.81 μg/l +/- 13.84; mean GSHPx activity was 186.96 μkat/l +/- 112.15. In late pregnancy cows, mean serum selenium concentration was 26.58 μg/l +/- 8.01, mean GSH-Px activity was 94.55 +/- 35.72 μkat/l. In calves, mean serum selenium concentration and GSH-Px activity were 30.41 μg/l +/- 12 and 219.54 μkat/l +/- 64.41, respectively. There was a statistically significant difference between the heifers and late pregnancy cows in both variables under study. However, between the late pregnancy cows and the calves, only the difference in GSH-Px activity was significant. The results indicate severe Se deficiency in the animals under study. It means apart from other things that mineral licks used did not provide enough minerals to meet the basic requirements of the animals.

Beginning SharePoint Designer 2010

CERN Document Server

Windischman, Woodrow W; Rehmani, Asif

2010-01-01

Teaching Web designers, developers, and IT professionals how to use the new version of SharePoint Designer. Covering both the design and business applications of SharePoint Designer, this complete Wrox guide brings readers thoroughly up to speed on how to use SharePoint Designer in an enterprise. You'll learn to create and modify web pages, use CSS editing tools to modify themes, use Data View to create interactivity with SharePoint and other data, and much more. Coverage includes integration points with Visual Studio, Visio, and InfoPath.: Shows web designers, developers, and IT professionals

SharePoint 2013 for dummies

CERN Document Server

Withee, Ken

2013-01-01

The bestselling guide on running SharePoint, now updated to cover all the new features of SharePoint 2013 SharePoint Portal Server is an essential part of the enterprise infrastructure for many businesses. Building on the success of previous versions of SharePoint For Dummies, this new edition covers all the latest features of SharePoint 2013 and provides you with an easy-to-understand resource for making the most of all that this version has to offer. You'll learn how to get a site up and running, branded, and populated with content, workflow, and management. In addition, t

Pro SharePoint 2010 Search

CERN Document Server

Noble, J; Bakman-Mikalski, Dan

2011-01-01

Pro SharePoint 2010 Search gives you expert advice on planning, deploying and customizing searches in SharePoint 2010. Drawing on the authors' extensive experience of working with real-world SharePoint deployments, this book teaches everything you'll need to know to create well-designed SharePoint solutions that always keep the end-user's experience in mind. Increase your search efficiency with SharePoint 2010's search functionality: extend the search user interface using third-party tools, and utilize analytics to improve relevancy. This practical hands-on book is a must-have resource for any

Effects of thyroid dysfunction and radiation exposure on some biochemical aspects in rats

International Nuclear Information System (INIS)

Mansour, S.Z.

2005-01-01

Radiation exposure effect associated with altered thyroid gland activity was investigated in rats. The results obtained showed that hypothyroidism was associated with low blood levels of free thyroxine (FT4), free triiodothyronine (FT3), high levels of thyroid stimulating hormone (TSH), decreased blood malondialdehyde level (MDA), increased glutathione peroxidase (GSH-Px) activity and hypocalcemia were observed. Hyperthyroidism was accompanied with high blood FT4 and FT3, low TSH levels, increased MDA levels, decreased GSH-Px activity, hypercalcaemia, low albumin level and A/G ratio were recorded. Globulin and vitamin E levels were not affected by the changes of animal thyroid states. In hypothyroid irradiated rats, although significant amelioration was recorded in blood GSH-Px activity and MDA contents, compared to hypothyroid rats, irradiation exaggerated the changes in FT4, FT3, TSH levels and also increased globulin and decreased vitamin E. Irradiation of hyperthyroid rats ameliorated hormones and albumin levels as compared to hyperthyroid rats. Despite of a decrease in blood vitamin E, the changes in MDA levels, GSH-Px activity and Ca levels were nearly similar to those recorded for hyperthyroid rats. According to the data obtained in the present study, it could be concluded that symptoms of hypothyroidism could be intensified by exposure to radiation

TauG-guidance of dynamic balance control during gait initiation in patients with chronic fatigue syndrome and fibromyalgia.

Science.gov (United States)

Rasouli, Omid; Stensdotter, Ann-Katrin; Van der Meer, Audrey L H

2016-08-01

Impaired postural control has been reported in static conditions in chronic fatigue syndrome and fibromyalgia, but postural control in dynamic tasks have not yet been investigated. Thus, we investigated measurements from a force plate to evaluate dynamic balance control during gait initiation in patients with chronic fatigue syndrome and fibromyalgia compared to matched healthy controls. Thirty female participants (10 per group) performed five trials of gait initiation. Center of pressure (CoP) trajectory of the initial weight shift onto the supporting foot in the mediolateral direction (CoPX) was analyzed using General Tau Theory. We investigated the hypothesis that tau of the CoPX motion-gap (τCoPx) is coupled onto an intrinsic tauG-guide (τG) by keeping the relation τCoPx=KτG, where K is a scaling factor that determines the relevant kinematics of a movement. Mean K values were 0.57, 0.55, and 0.50 in fibromyalgia, chronic fatigue syndrome, and healthy controls, respectively. Both patient groups showed K values significantly higher than 0.50 (P0.5). The findings revealed a lower level of dynamic postural control in both fibromyalgia and chronic fatigue syndrome compared to controls. Copyright © 2016 Elsevier Ltd. All rights reserved.

State-specific transport properties of electronically excited Ar and C

Science.gov (United States)

Istomin, V. A.; Kustova, E. V.

2018-05-01

In the present study, a theoretical model of state-resolved transport properties in electronically excited atomic species developed earlier is applied to argon and carbon atomic species. It is shown that for Ar and C, similarly to the case of atomic nitrogen and oxygen, the Slater-like models can be applied to calculate diameters of electronically excited atoms. Using the Slater-like model it is shown that for half-filled N (2 px1py1pz1) and full-filled Ar (3 px2py2pz2) electronic shells the growth of atomic radius goes slowly compared to C (2 px1py1) and O (2 px2py1pz1). The effect of collision diameters on the transport properties of Ar and C is evaluated. The influence of accounted number of electronic levels on the transport coefficients is examined for the case of Boltzmann distributions over electronic energy levels. It is emphasized that in the temperature range 1000-14000 K, for Boltzmann-like distributions over electronic states the number of accounted electronic levels do not influence the transport coefficients. Contrary to this, for higher temperatures T > 14000 K this effect becomes of importance, especially for argon.

Prevalence of estrogen receptor alpha PvuII and XbaI polymorphism in population of Polish postmenopausal women.

Directory of Open Access Journals (Sweden)

Jozef Haczynski

2008-01-01

Full Text Available Numerous data indicate that polymorphism of estrogen receptor alpha (ERalpha may predict lipid levels, lipid response to hormone replacement therapy (HRT, myocardial infarction risk, bone fracture risk, bone mineral density (BMD and changes in BMD over time. In this study we aimed to evaluate distribution of ERalpha PvuII and XbaI genotypes in population of Polish postmenopausal women qualified to different protocols of HRT. Subject of the study were 64 consecutive postmenopausal women aged from 45 to 65 years (mean 56.6 assigned to HRT. ERalpha PvuII and XbaI polymorphism was determined by PCR-restriction fragment length polymorphism (RFLP. The absence of PvuII and XbaI restriction sites were indicated by "P" and "X" and presence by "p" and "x", respectively. PvuII genotype was distributed as follows: PP 17.2% (n=11, Pp 50% (n=32, pp 32.83% (n=21. Frequency of XbaI genotype was: XX 6.25% (n=4, Xx 34.4% (n=22, xx 59.4% (n=38. Four haplotypes with following frequencies were recognized: PX 17.3%, px 47.4%, Px 24.4% and pX 10.9%. Prevalence of estrogen receptor alpha PvuII and XbaI polymorphisms in Polish women is similar to previously studied population.

The electronic structure of Ga As1-xPx and Ga Sb1-xPx calculated using the recursion method

International Nuclear Information System (INIS)

El-Hasan, M.; Tomak, M.

1988-10-01

The electronic structure calculation of Ga As 1-x P x and Ga Sb 1-x P x alloys using the recursion method is reported. A five orbitals, sp 3 s*, per atom model is used in the tight-binding representation of the Hamiltonian. The local density of states are calculated for Ga, As, Sb and P-sites, in a cluster of 216 atoms, the results are reasonably in good agreement with previous calculations. (author). 12 refs, 8 figs, 1 tab

On Motion Planning for Point-to-Point Maneuvers for a Class of Sailing Vehicles

DEFF Research Database (Denmark)

Xiao, Lin; Jouffroy, Jerome

2011-01-01

Despite their interesting dynamic and controllability properties, sailing vehicles have not been much studied in the control community. In this paper, we investigate motion planning of such vehicles. Starting from a simple dynamic model of sailing vessels in one dimension, this paper first...... considers their associated controllability issues, with the so-called no-sailing zone as a starting point, and it links them with a motion planning strategy using two-point boundary value problems as the main mathematical tool. This perspective is then expanded to do point-to-point maneuvers of sailing...

Making Sense of Boiling Points and Melting Points

Indian Academy of Sciences (India)

GENERAL | ARTICLE. The boiling and melting points of a pure substance are char- ... bonds, which involves high energy and hence high temperatures. Among the .... with zero intermolecular force at all temperatures and pressures, which ...

Octopuses use a human-like strategy to control precise point-to-point arm movements.

Science.gov (United States)

Sumbre, Germán; Fiorito, Graziano; Flash, Tamar; Hochner, Binyamin

2006-04-18

One of the key problems in motor control is mastering or reducing the number of degrees of freedom (DOFs) through coordination. This problem is especially prominent with hyper-redundant limbs such as the extremely flexible arm of the octopus. Several strategies for simplifying these control problems have been suggested for human point-to-point arm movements. Despite the evolutionary gap and morphological differences, humans and octopuses evolved similar strategies when fetching food to the mouth. To achieve this precise point-to-point-task, octopus arms generate a quasi-articulated structure based on three dynamic joints. A rotational movement around these joints brings the object to the mouth . Here, we describe a peripheral neural mechanism-two waves of muscle activation propagate toward each other, and their collision point sets the medial-joint location. This is a remarkably simple mechanism for adjusting the length of the segments according to where the object is grasped. Furthermore, similar to certain human arm movements, kinematic invariants were observed at the joint level rather than at the end-effector level, suggesting intrinsic control coordination. The evolutionary convergence to similar geometrical and kinematic features suggests that a kinematically constrained articulated limb controlled at the level of joint space is the optimal solution for precise point-to-point movements.

A MARKED POINT PROCESS MODEL FOR VEHICLE DETECTION IN AERIAL LIDAR POINT CLOUDS

Directory of Open Access Journals (Sweden)

A. Börcs

2012-07-01

Full Text Available In this paper we present an automated method for vehicle detection in LiDAR point clouds of crowded urban areas collected from an aerial platform. We assume that the input cloud is unordered, but it contains additional intensity and return number information which are jointly exploited by the proposed solution. Firstly, the 3-D point set is segmented into ground, vehicle, building roof, vegetation and clutter classes. Then the points with the corresponding class labels and intensity values are projected to the ground plane, where the optimal vehicle configuration is described by a Marked Point Process (MPP model of 2-D rectangles. Finally, the Multiple Birth and Death algorithm is utilized to find the configuration with the highest confidence.

Recent progress in fission at saddle point and scission point

International Nuclear Information System (INIS)

Blons, J.; Paya, D.; Signarbieux, C.

High resolution measurements of 230 Th and 232 Th fission cross sections for neutrons exhibit a fine structure. Such a structure is interpreted as a superposition of two rotational bands in the third, asymmetric, well of the fission barrier. The fragment mass distribution in the thermal fission of 235 U and 233 U does not show any even-odd effect, even at the highest kinetic energies. This is the mark of a strong viscosity in the descent from saddle point to scission point [fr

The algorithm to generate color point-cloud with the registration between panoramic image and laser point-cloud

International Nuclear Information System (INIS)

Zeng, Fanyang; Zhong, Ruofei

2014-01-01

Laser point cloud contains only intensity information and it is necessary for visual interpretation to obtain color information from other sensor. Cameras can provide texture, color, and other information of the corresponding object. Points with color information of corresponding pixels in digital images can be used to generate color point-cloud and is conducive to the visualization, classification and modeling of point-cloud. Different types of digital cameras are used in different Mobile Measurement Systems (MMS).the principles and processes for generating color point-cloud in different systems are not the same. The most prominent feature of the panoramic images is the field of 360 degrees view angle in the horizontal direction, to obtain the image information around the camera as much as possible. In this paper, we introduce a method to generate color point-cloud with panoramic image and laser point-cloud, and deduce the equation of the correspondence between points in panoramic images and laser point-clouds. The fusion of panoramic image and laser point-cloud is according to the collinear principle of three points (the center of the omnidirectional multi-camera system, the image point on the sphere, the object point). The experimental results show that the proposed algorithm and formulae in this paper are correct

Publication point indicators

DEFF Research Database (Denmark)

Elleby, Anita; Ingwersen, Peter

2010-01-01

The paper presents comparative analyses of two publication point systems, The Norwegian and the in-house system from the interdiscplinary Danish Institute for International Studies (DIIS), used as case in the study for publications published 2006, and compares central citation-based indicators...... with novel publication point indicators (PPIs) that are formalized and exemplified. Two diachronic citation windows are applied: 2006-07 and 2006-08. Web of Science (WoS) as well as Google Scholar (GS) are applied to observe the cite delay and citedness for the different document types published by DIIS...... for all document types. Statistical significant correlations were only found between WoS and GS and the two publication point systems in between, respectively. The study demonstrates how the nCPPI can be applied to institutions as evaluation tools supplementary to JCI in various combinations...

Do acupuncture points exist?

International Nuclear Information System (INIS)

Yan Xiaohui; Zhang Xinyi; Liu Chenglin; Dang, Ruishan; Huang Yuying; He Wei; Ding Guanghong

2009-01-01

We used synchrotron x-ray fluorescence analysis to probe the distribution of four chemical elements in and around acupuncture points, two located in the forearm and two in the lower leg. Three of the four acupuncture points showed significantly elevated concentrations of elements Ca, Fe, Cu and Zn in relation to levels in the surrounding tissue, with similar elevation ratios for Cu and Fe. The mapped distribution of these elements implies that each acupuncture point seems to be elliptical with the long axis along the meridian. (note)

Do acupuncture points exist?

Energy Technology Data Exchange (ETDEWEB)

Yan Xiaohui; Zhang Xinyi [Department of Physics, Surface Physics Laboratory (State Key Laboratory), and Synchrotron Radiation Research Center of Fudan University, Shanghai 200433 (China); Liu Chenglin [Physics Department of Yancheng Teachers' College, Yancheng 224002 (China); Dang, Ruishan [Second Military Medical University, Shanghai 200433 (China); Huang Yuying; He Wei [Beijing Synchrotron Radiation Facility, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100039 (China); Ding Guanghong [Shanghai Research Center of Acupuncture and Meridian, Pudong, Shanghai 201203 (China)

2009-05-07

We used synchrotron x-ray fluorescence analysis to probe the distribution of four chemical elements in and around acupuncture points, two located in the forearm and two in the lower leg. Three of the four acupuncture points showed significantly elevated concentrations of elements Ca, Fe, Cu and Zn in relation to levels in the surrounding tissue, with similar elevation ratios for Cu and Fe. The mapped distribution of these elements implies that each acupuncture point seems to be elliptical with the long axis along the meridian. (note)

Tipping Point

Science.gov (United States)

... Point by CPSC Blogger September 22, 2009 appliance child Childproofing CPSC danger death electrical fall furniture head injury product safety television tipover tv Watch the video in Adobe Flash ...

Surface chemistry of PH 3, PF 3 and PCl 3 on Ru(0001)

Science.gov (United States)

Tao, H.-S.; Diebold, U.; Shinn, N. D.; Madey, T. E.

1994-06-01

The adsorption, desorption and decomposition of PH 3, PF 3 and PCl 3 on Ru(0001) have been studied by soft X-ray photoelectron spectroscopy (SXPS) using synchrotron radiation. Due to large chemical shifts in the P 2p core levels, different phosphorus containing surface species can be identified. We find that PF 3 adsorbs molecularly on Ru(0001) at 80 and 300 K. At 80 K, PH 3 saturates the surface with one layer of atomic hydrogen, elemental phosphorus, subhydride (i.e., PHx (0 PH 3, with a total phosphorus coverage of 0.4 ML. At 300 K, PH 3 decomposes into atomic hydrogen and elemental phosphorus with a phosphorus coverage of 0.8 ML. At 80 K, PCl 3 adsorbs dissociatively into atomic chlorine, elemental phosphorus, PCl and possibly PCl 2 and PCl 3 in the first monolayer. Formation of multilayers of PCl 3 is observed at 80 K. At 300 K, PCl 3 adsorbs dissociatively as atomic chlorine and elemental phosphorus with a saturation phosphorus coverage of 0.1 ML. The variation in total phosphorus uptake at 300 K from PX3 ( X = H, FandCl) adsorption is a result of competition between site blocking by dissociation fragments and displacement reactions. Annealing surfaces with adsorbed phosphorus to 1000 K results in formation of RuzP ( z = 1 or 2), which is manifested by the chemical shifts in the P2p core level, as well as the P LVV Auger transition. The recombination of adsorbed phosphorus and adsorbed X ( = H, FandCl) from decomposition is also observed, but is a minor reaction channel on the surface. Thermochemical data are used to analyze the different stabilities of PX 3 at 300 K, namely, PF 3 adsorbs molecularly and PH 3 and PCl 3 dissociate completely. First, we compare the heat of molecular adsorption and the heat of dissociative adsorption of PX 3 on Ru(0001), using an enthalpy approach, and find results consistent with experimental observations. Second, we compare the total bond energy difference between molecular adsorption and complete dissociation of PX 3 on Ru

Pseudo-dynamic source modelling with 1-point and 2-point statistics of earthquake source parameters

KAUST Repository

Song, S. G.; Dalguer, L. A.; Mai, Paul Martin

2013-01-01

statistical framework that governs the finite-fault rupture process with 1-point and 2-point statistics of source parameters in order to quantify the variability of finite source models for future scenario events. We test this method by extracting 1-point

PowerPoint 2013 bible

CERN Document Server

Wempen, Faithe

2013-01-01

Master PowerPoint and improve your presentation skills with one book! In today's business climate, you need to know PowerPoint inside and out, and that's not all. You also need to be able to make a presentation that makes an impact. From using sophisticated transitions and animation in your PowerPoint presentations to interfacing in person with your audience, this information-packed book helps you succeed. Start creating professional-quality slides that captivate audiences and discover essential tips and techniques for making first-rate presentations, whether you're at a podium or

December 2002 Lidar Point Data of Southern California Coastline: Dana Point to Point La Jolla

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains lidar point data (latitude and longitude) from a strip of Southern California coastline (including water, beach, cliffs, and top of cliffs)...

April 2004 Lidar Point Data of Southern California Coastline: Dana Point to Point La Jolla

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains lidar point data (Geodetic Coordinates) from a strip of Southern California coastline (including water, beach, cliffs, and top of cliffs) from...

March 2003 Lidar Point Data of Southern California Coastline: Dana Point to Point La Jolla

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains lidar point data (Geodetic Coordinates) from a strip of Southern California coastline (including water, beach, cliffs, and top of cliffs) from...

Computing bubble-points of CO

NARCIS (Netherlands)

Ramdin, M.; Balaji, S.P.; Vicent Luna, J.M.; Torres-Knoop, A; Chen, Q.; Dubbeldam, D.; Calero, S; de Loos, T.W.; Vlugt, T.J.H.

2016-01-01

Computing bubble-points of multicomponent mixtures using Monte Carlo simulations is a non-trivial task. A new method is used to compute gas compositions from a known temperature, bubble-point pressure, and liquid composition. Monte Carlo simulations are used to calculate the bubble-points of

Magnonic triply-degenerate nodal points

Science.gov (United States)

Owerre, S. A.

2017-12-01

We generalize the concept of triply-degenerate nodal points to non-collinear antiferromagnets. Here, we introduce this concept to insulating quantum antiferromagnets on the decorated honeycomb lattice, with spin-1 bosonic quasiparticle excitations known as magnons. We demonstrate the existence of magnonic surface states with constant energy contours that form pairs of magnonic arcs connecting the surface projection of the magnonic triple nodal points. The quasiparticle excitations near the triple nodal points represent three-component bosons beyond that of magnonic Dirac, Weyl, and nodal-line cases. They can be regarded as a direct reflection of the intrinsic spin carried by magnons. Furthermore, we show that the magnonic triple nodal points can split into magnonic Weyl points, as the system transits from a non-collinear spin structure to a non-coplanar one with a non-zero scalar spin chirality. Our results not only apply to insulating antiferromagnets, but also provide a platform to seek for triple nodal points in metallic antiferromagnets.

Fermat's point from five perspectives

Science.gov (United States)

Park, Jungeun; Flores, Alfinio

2015-04-01

The Fermat point of a triangle is the point such that minimizes the sum of the distances from that point to the three vertices. Five approaches to study the Fermat point of a triangle are presented in this article. First, students use a mechanical device using masses, strings and pulleys to study the Fermat point as the one that minimizes the potential energy of the system. Second, students use soap films between parallel planes connecting three pegs. The tension on the film will be minimal when the sum of distances is minimal. Third, students use an empirical approach, measuring distances in an interactive GeoGebra page. Fourth, students use Euclidean geometry arguments for two proofs based on the Torricelli configuration, and one using Viviani's Theorem. And fifth, the kinematic method is used to gain additional insight on the size of the angles between the segments joining the Fermat point with the vertices.

Coronary artery disease, left ventricular hypertrophy and diastolic dysfunction are associated with stroke in patients affected by persistent non-valvular atrial fibrillation: a case-control study

Directory of Open Access Journals (Sweden)

Andrea Passantino

2009-04-01

Full Text Available Persistent non-valvular atrial fibrillation (NVAF is associated with an increased risk of cardiovascular events such as stroke, and its rate is expected to rise because of the ageing population. The absolute rate of stroke depends on age and comorbidity. Risk stratification for stroke in patients with NVAF derives from populations enrolled in randomized clinical trials. However, participants in clinical trials are often not representative of the general population. Many stroke risk stratification scores have been used, but they do not include transthoracic echocardiogram (TTE, pulsate wave Doppler (PWD and tissue Doppler imaging (TDI, simple and non-invasive diagnostic tools. The role of TTE, PWD and TDI findings has not been previously determined. Our study goal was to determine the association between TTE and PWD findings and stroke prevalence in a population of NVAF prone outpatients. Patients were divided into two groups: P for stroke prone and F for stroke free. There were no statistically significant differences between the two groups concerning cardiovascular risk factors, age (p=0.2, sex (p=0.2, smoking (p=0.3, diabetes (p=0.1 and hypercholesterolemia (p=0.2; hypertension was statistically significant (p less than 0.001. There were statistically significant differences concerning coronary artery disease, previous acute myocardial infarction (AMI (p px; ">less than 0.05 and non- AMI coronaropathy (p less than 0.04, a higher rate being in the P group. Concerning echo-Doppler findings, a higher statistically significant rate of left ventricular hypertrophy (LVH (ppx;"> px;">less than  0.05 and left ventricular diastolic dysfunction (ppx;"> px;">less than 0.001 was found in the P group and dilated left atrium (ppx;"> px

Point card compatible automatic vending machine for canned drink; Point card taio kan jido hanbaiki

Energy Technology Data Exchange (ETDEWEB)

NONE

2000-01-10

A point card compatible automatic vending machine for canned drinks is developed, which provides drink manufacturers with a powerful tool to acquire selling sites and attract consumers. Since the machine is equipped with a device to handle point cards, regular customers have increased and sales have picked up. A point card issuing device is also installed, and the new machine issues a point card whenever a customer wants. The drink manufacturers are evaluating high of the vending machine because it will contribute to the diffusion of the point card system and because a sales promotion campaign may be conducted through the vending machine for instance by exchanging a fully marked card with a giveaway on the spot. In the future, a bill validator (paper money identifier) will be integrated even with small size machines for the diffusion of point card compatible machines. (translated by NEDO)

SharePoint governance

OpenAIRE

Ali, Mudassar

2013-01-01

Masteroppgave i informasjons- og kommunikasjonsteknologi IKT590 2013 – Universitetet i Agder, Grimstad SharePoint is a web-based business collaboration platform from Microsoft which is very robust and dynamic in nature. The platform has been in the market for more than a decade and has been adapted by large number of organisations in the world. The platform has become larger in scale, richer in features and is improving consistently with every new version. However, SharePoint ...

Solving discrete zero point problems

NARCIS (Netherlands)

van der Laan, G.; Talman, A.J.J.; Yang, Z.F.

2004-01-01

In this paper an algorithm is proposed to .nd a discrete zero point of a function on the collection of integral points in the n-dimensional Euclidean space IRn.Starting with a given integral point, the algorithm generates a .nite sequence of adjacent integral simplices of varying dimension and

Error Mitigation of Point-to-Point Communication for Fault-Tolerant Computing

Science.gov (United States)

Akamine, Robert L.; Hodson, Robert F.; LaMeres, Brock J.; Ray, Robert E.

2011-01-01

Fault tolerant systems require the ability to detect and recover from physical damage caused by the hardware s environment, faulty connectors, and system degradation over time. This ability applies to military, space, and industrial computing applications. The integrity of Point-to-Point (P2P) communication, between two microcontrollers for example, is an essential part of fault tolerant computing systems. In this paper, different methods of fault detection and recovery are presented and analyzed.

Befolkningsudviklingen (Population Development)

DEFF Research Database (Denmark)

Nørgaard, Jørgen

2010-01-01

The article takes the 1972 report, The Limits to Growth as its starting point, briefly explaining the Systam Dynamics model used for the report's analyses. Focus is on the important role of population. The simple model of I = PxAxT, where I is the environmental Impact, P population......, A is the Affluence and T the ecoimpact-intensity of the Technology used. Various scenarios ar shown, illustrating how a choice of 1.6 birth per woman on average instead of 2.6 birth, will in 2150 result in 3.6 billion people on earth instead of 27 billions. The article warns against the believe that growth in GDP...

Dew point vs bubble point : a misunderstood constraint on gravity drainage processes

Energy Technology Data Exchange (ETDEWEB)

Nenninger, J. [N-Solv Corp., Calgary, AB (Canada); Gunnewiek, L. [Hatch Ltd., Mississauga, ON (Canada)

2009-07-01

This study demonstrated that gravity drainage processes that use blended fluids such as solvents have an inherently unstable material balance due to differences between dew point and bubble point compositions. The instability can lead to the accumulation of volatile components within the chamber, and impair mass and heat transfer processes. Case studies were used to demonstrate the large temperature gradients within the vapour chamber caused by temperature differences between the bubble point and dew point for blended fluids. A review of published data showed that many experiments on in-situ processes do not account for unstable material balances caused by a lack of steam trap control. A study of temperature profiles during steam assisted gravity drainage (SAGD) studies showed significant temperature depressions caused by methane accumulations at the outside perimeter of the steam chamber. It was demonstrated that the condensation of large volumes of purified solvents provided an efficient mechanism for the removal of methane from the chamber. It was concluded that gravity drainage processes can be optimized by using pure propane during the injection process. 22 refs., 1 tab., 18 figs.

Dew Point

OpenAIRE

Goldsmith, Shelly

1999-01-01

Dew Point was a solo exhibition originating at PriceWaterhouseCoopers Headquarters Gallery, London, UK and toured to the Centre de Documentacio i Museu Textil, Terrassa, Spain and Gallery Aoyama, Tokyo, Japan.

Tipping Point

Medline Plus

Full Text Available ... Point by CPSC Blogger September 22, 2009 appliance child Childproofing CPSC danger death electrical fall furniture head injury product safety television tipover tv Watch the video in Adobe Flash ...

PowerPoint 2007 for Dummies

CERN Document Server

Lowe, Doug

2007-01-01

New and inexperienced PowerPoint users will discover how to use the latest enhancements to PowerPoint 2007 quickly and efficiently so that they can produce unique and informative presentations PowerPoint continues to be the world's most popular presentation software This updated For Dummies guide shows users different ways to create powerful and effective slideshow presentations that incorporate data from other applications in the form of charts, clip art, sound, and video Shares the key features of PowerPoint 2007 including creating and editing slides, working with hyperlinks and action butt

Beginning SharePoint 2010 Development

CERN Document Server

Fox, Steve

2010-01-01

Discover how to take advantage of the many new features in SharePoint 2010. SharePoint provides content management (enterprise content management, Web content management, records management, and more), workflow, and social media features, and the new version boasts enhanced capabilities. This introductory-level book walks you through the process of learning, developing, and deploying SharePoint 2010 solutions. You'll leverage your existing skills and tools to grasp the fundamental programming concepts and practices of SharePoint 2010. The author clearly explains how to develop your first appli

Professional SharePoint 2013 development

CERN Document Server

Alirezaei, Reza; Ranlett, Matt; Hillier, Scot; Wilson, Brian; Fried, Jeff; Swider, Paul

2013-01-01

Thorough coverage of development in SharePoint 2013 A team of well-known Microsoft MVPs joins forces in this fully updated resource, providing you with in-depth coverage of development tools in the latest iteration of the immensely popular SharePoint. From building solutions to building custom workflow and content management applications, this book shares field-tested best practices on all aspect of SharePoint 2013 development. Offers a thorough look at Windows Azure and SharePoint 2013Includes new chapters on Application Life Cycle Management, developing apps in ShareP

The power of PowerPoint.

Science.gov (United States)

Niamtu , J

2001-08-01

Carousel slide presentations have been used for academic and clinical presentations since the late 1950s. However, advances in computer technology have caused a paradigm shift, and digital presentations are quickly becoming standard for clinical presentations. The advantages of digital presentations include cost savings; portability; easy updating capability; Internet access; multimedia functions, such as animation, pictures, video, and sound; and customization to augment audience interest and attention. Microsoft PowerPoint has emerged as the most popular digital presentation software and is currently used by many practitioners with and without significant computer expertise. The user-friendly platform of PowerPoint enables even the novice presenter to incorporate digital presentations into his or her profession. PowerPoint offers many advanced options that, with a minimal investment of time, can be used to create more interactive and professional presentations for lectures, patient education, and marketing. Examples of advanced PowerPoint applications are presented in a stepwise manner to unveil the full power of PowerPoint. By incorporating these techniques, medical practitioners can easily personalize, customize, and enhance their PowerPoint presentations. Complications, pitfalls, and caveats are discussed to detour and prevent misadventures in digital presentations. Relevant Web sites are listed to further update, customize, and communicate PowerPoint techniques.

Photoacoustic Point Source

International Nuclear Information System (INIS)

Calasso, Irio G.; Craig, Walter; Diebold, Gerald J.

2001-01-01

We investigate the photoacoustic effect generated by heat deposition at a point in space in an inviscid fluid. Delta-function and long Gaussian optical pulses are used as sources in the wave equation for the displacement potential to determine the fluid motion. The linear sound-generation mechanism gives bipolar photoacoustic waves, whereas the nonlinear mechanism produces asymmetric tripolar waves. The salient features of the photoacoustic point source are that rapid heat deposition and nonlinear thermal expansion dominate the production of ultrasound

Proton production from Si+Au collisions at 14.5 A/center dot/GeV

International Nuclear Information System (INIS)

Sarabura, M.; Abbott, T.; Akiba, Y.

1988-01-01

Recent results are presented from the study of central Si+Au → p+X, Si+Au → π/sup +-/+X, and Si+Cu → p+X at 14.5 A/center dot/GeV. The distribution of protons in rapidity indicates that many target protons are found above 0.5 units. The variation of the slope parameter in rapidity is consistent with a thermal source of protons at the geometric center-of-mass rapidity. 4 refs., 4 figs

The transition to electronic communications networks in the secondary treasury market

OpenAIRE

Bruce Mizrach; Christopher J. Neely

2006-01-01

This article reviews the history of the recent shift to electronic trading in equity, foreign exchange, and fixed-income markets. The authors analyze a new data set: the eSpeed electronic Treasury network. They contrast the market microstructure of the eSpeed trading platform with the traditional voice-assisted networks that report through GovPX. The electronic market (eSpeed) has greater volume, smaller spreads, and a lower estimated trade impact than the voice market (GovPX). ; Appeared ear...

Sets of Fourier coefficients using numerical quadrature

International Nuclear Information System (INIS)

Lyness, J. N.

2001-01-01

One approach to the calculation of Fourier trigonometric coefficients f(r) of a given function f(x) is to apply the trapezoidal quadrature rule to the integral representation f(r)=(line i ntegral)(sub 0)(sup 1) f(x)e(sup -2(pi)irx)dx. Some of the difficulties in this approach are discussed. A possible way of overcoming many of these is by means of a subtraction function. Thus, one sets f(x)= h(sub p-1)(x)+ g(sub p)(x), where h(sub -1)(x) is an algebraic polynomial of degree p-1, specified in such a way that the Fourier series of g(sub p)(x) converges more rapidly than that of f(x). To obtain the Fourier coefficients of f(x), one uses an analytic expression for those of h(sub p-1)(x) and numerical quadrature to approximately those of g(sub p)(x)

Pseudo-dynamic source modelling with 1-point and 2-point statistics of earthquake source parameters

KAUST Repository

Song, S. G.

2013-12-24

Ground motion prediction is an essential element in seismic hazard and risk analysis. Empirical ground motion prediction approaches have been widely used in the community, but efficient simulation-based ground motion prediction methods are needed to complement empirical approaches, especially in the regions with limited data constraints. Recently, dynamic rupture modelling has been successfully adopted in physics-based source and ground motion modelling, but it is still computationally demanding and many input parameters are not well constrained by observational data. Pseudo-dynamic source modelling keeps the form of kinematic modelling with its computational efficiency, but also tries to emulate the physics of source process. In this paper, we develop a statistical framework that governs the finite-fault rupture process with 1-point and 2-point statistics of source parameters in order to quantify the variability of finite source models for future scenario events. We test this method by extracting 1-point and 2-point statistics from dynamically derived source models and simulating a number of rupture scenarios, given target 1-point and 2-point statistics. We propose a new rupture model generator for stochastic source modelling with the covariance matrix constructed from target 2-point statistics, that is, auto- and cross-correlations. Our sensitivity analysis of near-source ground motions to 1-point and 2-point statistics of source parameters provides insights into relations between statistical rupture properties and ground motions. We observe that larger standard deviation and stronger correlation produce stronger peak ground motions in general. The proposed new source modelling approach will contribute to understanding the effect of earthquake source on near-source ground motion characteristics in a more quantitative and systematic way.

Pharmacological characterization of a β-adrenergic-like octopamine receptor in Plutella xylostella.

Science.gov (United States)

Huang, Qing-Ting; Ma, Hai-Hao; Deng, Xi-Le; Zhu, Hang; Liu, Jia; Zhou, Yong; Zhou, Xiao-Mao

2018-04-25

The β-adrenergic-like octopamine receptor (OA2B2) belongs to the class of G-protein coupled receptors. It regulates important physiological functions in insects, thus is potentially a good target for insecticides. In this study, the putative open reading frame sequence of the Pxoa2b2 gene in Plutella xylostella was cloned. Orthologous sequence alignment, phylogenetic tree analysis, and protein sequence analysis all showed that the cloned receptor belongs to the OA2B2 protein family. PxOA2B2 was transiently expressed in HEK-293 cells. It was found that PxOA2B2 could be activated by both octopamine and tyramine, resulting in increased intracellular cyclic AMP (cAMP) levels, whereas dopamine and serotonin were not effective in eliciting cAMP production. Further studies with series of PxOA2B2 agonists and antagonists showed that all four tested agonists (e.g., naphazoline, clonidine, 2-phenylethylamine, and amitraz) could activate the PxOA2B2 receptor, and two of tested antagonists (e.g., phentolamine and mianserin) had significant antagonistic effects. However, antagonist of yohimbine had no effects. Quantitative real-time polymerase chain reaction analysis showed that Pxoa2b2 gene was expressed in all developmental stages of P. xylostella and that the highest expression occurred in male adults. Further analysis with fourth-instar P. xylostella larvae showed that the Pxoa2b2 gene was mainly expressed in Malpighian tubule, epidermal, and head tissues. This study provides both a pharmacological characterization and the gene expression patterns of the OA2B2 in P. xylostella, facilitating further research for insecticides using PxOA2B2 as a target. © 2018 Wiley Periodicals, Inc.

Microseismic monitoring during Hydraulic stimulation in Pohang (Korea) for EGS pilot project

Science.gov (United States)

Kim, M.; Yoon, B.; Lee, C.; Park, K. G.; Yoon, W. S.; Song, Y.; Lee, T. J.

2017-12-01

Since the geothermal anomaly in the Pohang area has been reported in 1960s, various geological and geophysical surveys have been conducted by Korea Institute of Geoscience and Mineral Resources (KIGAM) including gravity, seismic, airborne magnetic and magneto-telluric surveys. Based on these explorations, the Enhanced Geothermal System (EGS) pilot project has been carried out in Pohang since the end of 2010. One vertical well (PX-2, MD 4,348 m) and one deviated well (PX-1, MD 4,362 m) have been drilled in granite rock for the EGS. Microseismic (MS) monitoring is the best way to understand how the fracture grows during the hydraulic stimulation. KIGAM has set up 9 shallow borehole stations (100-130 m), 4 surface stations and two borehole geophones (1,350 and 1,550 m deep) within 5 km radius from injection well for the MS monitoring during hydraulic stimulation. The first hydraulic stimulation started on January 29th to February 20th, 2016 at PX-2 and the second stimulation was conducted in PX-1 from December 15th, 2016 to January 11th, 2017. Several hundreds of MS events occurred during stimulation and the biggest event was ML 2.3 during the shut in period of the second stimulation. Based on the results of the MS monitoring, a soft stimulation is scheduled at PX-1 in cooperation with one of the European Horizon2020 project, DESTRESS (Demonstration of soft stimulation treatments of geothermal reservoirs). We will present the MS monitoring system in Pohang and the data of the stimulation with the MS monitoring results. We believe that the data from Pohang will improve the understanding of seismic behavior due to hydraulic stimulation in crystalline rocks and also will contribute to success of the Pohang EGS project.

SharePoint 2010 Six-in-One

CERN Document Server

Geier, Chris; Bertram, Becky

2011-01-01

A team of SharePoint authorities addresses the six most essential areas of SharePoint 2010. SharePoint enables Web sites to host shared workspaces and is a leading solution for Enterprise Content Management. This book serves as one-stop shopping for concise coverage on six key areas that you need to know in order to get up and running with SharePoint 2010 quickly. After an introduction to the new features of SharePoint 2010, the author team of SharePoint experts walk you through branding and customization, workflow, business connectivity services, social networking and tools, the search functi

18 CFR 157.211 - Delivery points.

Science.gov (United States)

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Delivery points. 157... for Certain Transactions and Abandonment § 157.211 Delivery points. (a) Construction and operation—(1... delivery point, excluding the construction of certain delivery points subject to the prior notice...

Backward exotic meson production in π-n→px--

International Nuclear Information System (INIS)

Mantell, D.

1978-01-01

A discussion is given of some of the theory and theoretical techniques as well as actual previous experiments for the study of π - + n → p + X -- interactions. Included are the forces, classification, inclusive reactions, quark diagrams, properties of the unobserved X, cross sections, exotic mesons, duality and crossing, the working and normalization of some actual rexperiments, and analysis. 10 references

Network Competition - the Coexistence of Hub-and-Spoke and Point-to-Point Systems

NARCIS (Netherlands)

Alderighi, M.; Cento, A.; Nijkamp, P.; Rietveld, P.

2005-01-01

The paper identifies conditions under which asymmetric equilibria may exist when carriers compete in designing their network configurations in a game-theoretical framework. Two carriers are assumed here, which are allowed to play three different strategies: Point-to-point (PP), hub-and-spoke (HS) or

Wolf Point Substation, Roosevelt County, Montana

International Nuclear Information System (INIS)

1991-05-01

The Western Area Power Administration (Western), an agency of the United States Department of Energy, is proposing to construct the 115-kV Wolf Point Substation near Wolf Point in Roosevelt County, Montana (Figure 1). As part of the construction project, Western's existing Wolf Point Substation would be taken out of service. The existing 115-kV Wolf Point Substation is located approximately 3 miles west of Wolf Point, Montana (Figure 2). The substation was constructed in 1949. The existing Wolf Point Substation serves as a ''Switching Station'' for the 115-kV transmission in the region. The need for substation improvements is based on operational and reliability issues. For this environmental assessment (EA), the environmental review of the proposed project took into account the removal of the old Wolf Point Substation, rerouting of the five Western lines and four lines from the Cooperatives and Montana-Dakota Utilities Company, and the new road into the proposed substation. Reference to the new proposed Wolf Point Substation in the EA includes these facilities as well as the old substation site. The environmental review looked at the impacts to all resource areas in the Wolf Point area. 7 refs., 6 figs

SharePoint 2007 Collaboration For Dummies

CERN Document Server

Harvey, Greg

2009-01-01

If you're looking for a way to help your teams access what they need to know, work together, and get the job done, SharePoint can do just that. SharePoint 2007 Collaboration For Dummies shows you the easiest way to set up and customize SharePoint, manage your data, interact using SharePoint blogs and wikis, integrate Office programs, and make your office more productive. You'll learn what SharePoint can do and how to make it work for your business, understand the technical terms, and enable your people to collaborate on documents and spreadsheets. You'll even discover how to get SharePoint hel

Calorimetry end-point predictions

International Nuclear Information System (INIS)

Fox, M.A.

1981-01-01

This paper describes a portion of the work presently in progress at Rocky Flats in the field of calorimetry. In particular, calorimetry end-point predictions are outlined. The problems associated with end-point predictions and the progress made in overcoming these obstacles are discussed. The two major problems, noise and an accurate description of the heat function, are dealt with to obtain the most accurate results. Data are taken from an actual calorimeter and are processed by means of three different noise reduction techniques. The processed data are then utilized by one to four algorithms, depending on the accuracy desired to determined the end-point

Tipping Point

Medline Plus

Full Text Available ... Point by CPSC Blogger September 22, 2009 appliance child Childproofing CPSC danger death electrical fall furniture head ... see news reports about horrible accidents involving young children and furniture, appliance and tv tip-overs. The ...

Tipping Point

Medline Plus

Full Text Available ... Point by CPSC Blogger September 22, 2009 appliance child Childproofing CPSC danger death electrical fall furniture head ... TV falls with about the same force as child falling from the third story of a building. ...

Tipping Point

Medline Plus

Full Text Available ... Tipping Point by CPSC Blogger September 22, 2009 appliance child Childproofing CPSC danger death electrical fall furniture ... about horrible accidents involving young children and furniture, appliance and tv tip-overs. The force of a ...

Generalized zero point anomaly

International Nuclear Information System (INIS)

Nogueira, Jose Alexandre; Maia Junior, Adolfo

1994-01-01

It is defined Zero point Anomaly (ZPA) as the difference between the Effective Potential (EP) and the Zero point Energy (ZPE). It is shown, for a massive and interacting scalar field that, in very general conditions, the renormalized ZPA vanishes and then the renormalized EP and ZPE coincide. (author). 3 refs

Cross sectional and longitudinal study on selenium, glutathione peroxidase, smoking, and occupational exposure in coal miners

Energy Technology Data Exchange (ETDEWEB)

Nadif, R.; Oryszczyn, M.P.; Fradier-Dusch, M.; Hellier, G.; Bertrand, J.P.; Pham, Q.T.; Kauffmann, F. [INSERM, Vandoeuvre-les-Nancy (France). Faculty of Medicine

2001-04-01

The aim of the study was to understand the variations of selenium (Se) concentration relative to changes in occupational exposure to coal dust, taking into account age and changes in smoking habits in miners surveyed twice, in 1990 and 1994. It was found that selenium concentration and glutathione peroxidase activities (GSH-Px) activities were significantly lower in active than in retired miners. Moreover, Se concentration was lower in miners exposed to high compared with those exposed to low dust concentrations. In miners exposed to high dust concentrations, Se concentration was significantly lower whereas erythrocyte GSH-Px activity was significantly higher in the subgroup with estimated cumulative exposure {gt} 68 mg/m{sup 3}.y. In all miners, plasma GSH-Px activity was correlated with Se concentration. The 4 year Se changes were negatively related to exposure to high dust concentrations and positively related to change in exposure from high to retirement and to change from smoker to ex-smoker. The variations of Se concentration in relation to changes in occupational exposure to coal dust and in smoking habits, and the close correlation found between plasma Se concentration and GSH-Px activity suggest that both are required in antioxidant defence. These results agree well with the hypothesis that the decrease in Se concentration reflects its use against reactive oxygen species generated by exposure to coal mine dust and by smoking.

Uncertainty analysis of point by point sampling complex surfaces using touch probe CMMs

DEFF Research Database (Denmark)

Barini, Emanuele; Tosello, Guido; De Chiffre, Leonardo

2007-01-01

The paper describes a study concerning point by point scanning of complex surfaces using tactile CMMs. A four factors-two level full factorial experiment was carried out, involving measurements on a complex surface configuration item comprising a sphere, a cylinder and a cone, combined in a singl...

WHO Standard Acupuncture Point Locations

Directory of Open Access Journals (Sweden)

Sabina Lim

2010-01-01

Full Text Available ‘WHO Standard Acupuncture Point Locations in the Western Pacific Region (WHO Standard was released in 2008. Initially, there were 92/361 controversial acupuncture points (acupoints. Through seven informal consultations and four task force team meetings, 86 points were agreed upon among the 92 controversial acupoints, leaving 6 remaining controversial acupoints, demanding active research in the future. This will enhance the reproducibility and validity of acupuncture studies. It will also lead to a better understanding of acupuncture mechanisms in order to optimize its clinical efficacy for a range of diseases and syndromes. This book has two parts: General Guidelines for Acupuncture Point Locations and WHO Standard Acupuncture Point Locations. First of all, familiarity with the General Guidelines for Acupuncture Point Locations in this book can help the reader to understand and use the contents of this book in depth. I would like to thank all of the participating experts and scholars for this great work, who have overcome the limits of previous acupuncture references. I also appreciate the dedicated effort and harmonious leadership of Dr Choi Seung-hoon, former Regional Adviser in Traditional Medicine of Western Pacific Office, WHO.

Two-sorted Point-Interval Temporal Logics

DEFF Research Database (Denmark)

Balbiani, Philippe; Goranko, Valentin; Sciavicco, Guido

2011-01-01

There are two natural and well-studied approaches to temporal ontology and reasoning: point-based and interval-based. Usually, interval-based temporal reasoning deals with points as particular, duration-less intervals. Here we develop explicitly two-sorted point-interval temporal logical framework...... whereby time instants (points) and time periods (intervals) are considered on a par, and the perspective can shift between them within the formal discourse. We focus on fragments involving only modal operators that correspond to the inter-sort relations between points and intervals. We analyze...

Experimental evidence for a vector-like behaviour of Pomeron exchange

CERN Document Server

Barberis, D.; Close, F.E.; Danielsen, K.M.; Donskov, S.V.; Earl, B.C.; Evans, D.; French, B.R.; Hino, T.; Inaba, S.; Jacholkowski, A.; Jacobsen, T.; Khaustov, G.V.; Kinson, J.B.; Kirk, A.; Kondashov, A.A.; Lednev, A.A.; Lenti, V.; Minashvili, I.; Peigneux, J.P.; Romanovsky, V.; Russakovich, N.; Semenov, A.; Shagin, P.M.; Shimizu, H.; Singovsky, A.V.; Sobol, A.; Stassinaki, M.; Stroot, J.P.; Takamatsu, K.; Tsuru, T.; Villalobos Baillie, O.; Votruba, M.F.; Yasu, Y.

1999-01-01

Evidence is presented that the Pomeron act as a non-conserved vector current. A study has been made of the azimuthal angle phi, which is defined as the angle between the pT vectors of the two outgoing protons, in the reaction pp -> pp(X0) for those resonances (X0) which are compatible with being produced by double Pomeron exchange. These distributions have been compared with a model which describes the Pomeron as a non-conserved vector current and a qualitative agreement is found. In addition, when one of the particles exchanged is known to have spin 0, namely pi-Pomeron exchange, the phi distribution is flat.

Effect of cation nature on development of Zn-, Cd- and Ca-zeolite catalysts during ethylbenzene transformations

International Nuclear Information System (INIS)

Tuan, K.Kh.; Berentsvejg, V.V.; Rudenko, A.P.; Tkhuan, N.T.; Topchieva, K.V.

1984-01-01

It is shown that in the course of ethylbenzene transformations at 650 deg, 0.25 7nY, 0.25CdY, 0.82CdY catalysts on the basis of Y-type zeolite are developed for the process of styrene formation accompanied by the accumulation of packing products (PP) and increase in styrene selectivity from 0 to 100%. It is shown that the nature of Me 2+ ion in zeolite is of great importance in the manifestation of the effect of catalyst development in the course of ethylbenzene transformations. Ions capable of PP formation and accumulation composing polymercatalyst complexes [PPxMe 2+ ] are active in this process

Derivation of Parathyroid Gland Cells and Their Progenitors fromInduced Pluripotent Stem Cells (iPSCs) for Personalized Therapy

Science.gov (United States)

2016-09-01

mRFP sequences derived from amplifying CFTRex27- mRFP-pUC19 into the GCM2 donor DNA. This template sequence contained a 2A peptide sequence immediately...Undigested px330 is the SP negative control. px330 is a chimeric sequence that contains both the gRNA and Cas9 sequence in a single plasmid construct...and shows the correct junction sequence between GCM2 exon 5 and the 2A Peptide . (C) Primary and secondary antibodies for immunostaining are shown

Past, present and future polarization experiments with deuterons

International Nuclear Information System (INIS)

Punjabi, V.; Perdrisat, C.F.

1996-01-01

Recent experimental data for the inclusive breakup reaction A(d, p)X, with emphasis on 1 H(d, p)X, and the backward elastic scattering reaction dp → pd are discussed. There is now a fairly complete data base for these reactions, with measurements of the differential cross section, the tensor analyzing power T 20 and the deuteron to proton polarization transfer k 0 . The relevance of these reactions to the study of the short range properties of the deuteron is estimated [ru

ACS Zero Point Verification

Science.gov (United States)

Dolphin, Andrew

2005-07-01

The uncertainties in the photometric zero points create a fundamental limit to the accuracy of photometry. The current state of the ACS calibration is surprisingly poor, with zero point uncertainties of 0.03 magnitudes. The reason for this is that the ACS calibrations are based primarily on semi-emprical synthetic zero points and observations of fields too crowded for accurate ground-based photometry. I propose to remedy this problem by obtaining ACS images of the omega Cen standard field with all nine broadband ACS/WFC filters. This will permit the direct determination of the ACS zero points by comparison with excellent ground-based photometry, and should reduce their uncertainties to less than 0.01 magnitudes. A second benefit is that it will facilitate the comparison of the WFPC2 and ACS photometric systems, which will be important as WFPC2 is phased out and ACS becomes HST's primary imager. Finally, three of the filters will be repeated from my Cycle 12 observations, allowing for a measurement of any change in sensitivity.

Usefulness of K-Point Injection for the Nonspecific Neck Pain in So-Called K-Point Syndrome.

Science.gov (United States)

Moon, Jeong Jae; Ahn, Myun Whan; Ahn, Hyo Sae; Lee, Sung Jun; Lee, Dong Yeol

2016-12-01

Shoichi Kokubun introduced his successful experience with local anesthetic injection at the occipital insertion of the sternocleidomastoid muscle in K-point syndrome. The purpose of this study was to evaluate the short-term and long-term effectiveness of K-point injection and investigate factors affecting treatment results. K-point injection was performed in 58 patients with K-point syndrome at Yeungnam University Medical Center. The syndrome was associated with cervical whiplash injury in 10 patients and was of nonspecific origin in the rest. One milliliter of 2% lidocaine mixed with 1 milliliter of dexamethasone was injected in 50 patients and 2 milliliters of 1% lidocaine alone in the rest. Initially, the severity of local tenderness at the K-point and other tender points was examined and the degree of immediate pain relief effect was assessed within 1 hour after injection. Early effect within 1 month after the injection and current effect were evaluated in 27 patients using a modified Kim's questionnaire with regard to the duration of improvement, degree of improvement in pain and daily living activities, and satisfaction. Of the total 58 patients, 44 (75.8%) apparently had immediate pain relief after K-point injection. The only factor associated with successful immediate pain relief was the whiplash injury associated with traffic accident (TA). The early pain control effect was associated with the immediate effect. The current effect was associated with the early effect alone. Satisfaction with the K-point injection was related to early successful pain relief. K-point injection would be useful for early pain relief in nonspecific neck pain syndrome so called K-point syndrome, but not for current pain relief. Especially, it was very effective for early pain control in the whiplash injury associated with TA.

Quantum Triple Point and Quantum Critical End Points in Metallic Magnets.

Science.gov (United States)

Belitz, D; Kirkpatrick, T R

2017-12-29

In low-temperature metallic magnets, ferromagnetic (FM) and antiferromagnetic (AFM) orders can exist, adjacent to one another or concurrently, in the phase diagram of a single system. We show that universal quantum effects qualitatively alter the known phase diagrams for classical magnets. They shrink the region of concurrent FM and AFM order, change various transitions from second to first order, and, in the presence of a magnetic field, lead to either a quantum triple point where the FM, AFM, and paramagnetic phases all coexist or a quantum critical end point.

Point defects in solids

International Nuclear Information System (INIS)

Anon.

1978-01-01

The principal properties of point defects are studied: thermodynamics, electronic structure, interactions with etended defects, production by irradiation. Some measuring methods are presented: atomic diffusion, spectroscopic methods, diffuse scattering of neutron and X rays, positron annihilation, molecular dynamics. Then points defects in various materials are investigated: ionic crystals, oxides, semiconductor materials, metals, intermetallic compounds, carbides, nitrides [fr

Detecting determinism from point processes.

Science.gov (United States)

Andrzejak, Ralph G; Mormann, Florian; Kreuz, Thomas

2014-12-01

The detection of a nonrandom structure from experimental data can be crucial for the classification, understanding, and interpretation of the generating process. We here introduce a rank-based nonlinear predictability score to detect determinism from point process data. Thanks to its modular nature, this approach can be adapted to whatever signature in the data one considers indicative of deterministic structure. After validating our approach using point process signals from deterministic and stochastic model dynamics, we show an application to neuronal spike trains recorded in the brain of an epilepsy patient. While we illustrate our approach in the context of temporal point processes, it can be readily applied to spatial point processes as well.

Detecting change-points in extremes

KAUST Repository

Dupuis, D. J.

2015-01-01

Even though most work on change-point estimation focuses on changes in the mean, changes in the variance or in the tail distribution can lead to more extreme events. In this paper, we develop a new method of detecting and estimating the change-points in the tail of multiple time series data. In addition, we adapt existing tail change-point detection methods to our specific problem and conduct a thorough comparison of different methods in terms of performance on the estimation of change-points and computational time. We also examine three locations on the U.S. northeast coast and demonstrate that the methods are useful for identifying changes in seasonally extreme warm temperatures.

Fixed-Point Configurable Hardware Components

Directory of Open Access Journals (Sweden)

Rocher Romuald

2006-01-01

Full Text Available To reduce the gap between the VLSI technology capability and the designer productivity, design reuse based on IP (intellectual properties is commonly used. In terms of arithmetic accuracy, the generated architecture can generally only be configured through the input and output word lengths. In this paper, a new kind of method to optimize fixed-point arithmetic IP has been proposed. The architecture cost is minimized under accuracy constraints defined by the user. Our approach allows exploring the fixed-point search space and the algorithm-level search space to select the optimized structure and fixed-point specification. To significantly reduce the optimization and design times, analytical models are used for the fixed-point optimization process.

Analysis of relationship between registration performance of point cloud statistical model and generation method of corresponding points

International Nuclear Information System (INIS)

Yamaoka, Naoto; Watanabe, Wataru; Hontani, Hidekata

2010-01-01

Most of the time when we construct statistical point cloud model, we need to calculate the corresponding points. Constructed statistical model will not be the same if we use different types of method to calculate the corresponding points. This article proposes the effect to statistical model of human organ made by different types of method to calculate the corresponding points. We validated the performance of statistical model by registering a surface of an organ in a 3D medical image. We compare two methods to calculate corresponding points. The first, the 'Generalized Multi-Dimensional Scaling (GMDS)', determines the corresponding points by the shapes of two curved surfaces. The second approach, the 'Entropy-based Particle system', chooses corresponding points by calculating a number of curved surfaces statistically. By these methods we construct the statistical models and using these models we conducted registration with the medical image. For the estimation, we use non-parametric belief propagation and this method estimates not only the position of the organ but also the probability density of the organ position. We evaluate how the two different types of method that calculates corresponding points affects the statistical model by change in probability density of each points. (author)

Fermion-induced quantum critical points.

Science.gov (United States)

Li, Zi-Xiang; Jiang, Yi-Fan; Jian, Shao-Kai; Yao, Hong

2017-08-22

A unified theory of quantum critical points beyond the conventional Landau-Ginzburg-Wilson paradigm remains unknown. According to Landau cubic criterion, phase transitions should be first-order when cubic terms of order parameters are allowed by symmetry in the Landau-Ginzburg free energy. Here, from renormalization group analysis, we show that second-order quantum phase transitions can occur at such putatively first-order transitions in interacting two-dimensional Dirac semimetals. As such type of Landau-forbidden quantum critical points are induced by gapless fermions, we call them fermion-induced quantum critical points. We further introduce a microscopic model of SU(N) fermions on the honeycomb lattice featuring a transition between Dirac semimetals and Kekule valence bond solids. Remarkably, our large-scale sign-problem-free Majorana quantum Monte Carlo simulations show convincing evidences of a fermion-induced quantum critical points for N = 2, 3, 4, 5 and 6, consistent with the renormalization group analysis. We finally discuss possible experimental realizations of the fermion-induced quantum critical points in graphene and graphene-like materials.Quantum phase transitions are governed by Landau-Ginzburg theory and the exceptions are rare. Here, Li et al. propose a type of Landau-forbidden quantum critical points induced by gapless fermions in two-dimensional Dirac semimetals.

Critical points in magnetic systems

International Nuclear Information System (INIS)

Bongaarts, A.L.M.

1975-01-01

The magnetical phase transitions of CsCoCl 3 .2H 2 O and CsCoCl 3 .2D 2 O are investigated by neutron diffraction techniques with special attention to the critical points in the phase diagrams. CsCoCl 3 .2H 2 O turned out to be a one-dimentional magnetic antiferromagnet with ferromagnetic and antiferromagnetic interactions. In the vicinity of the Neel point, the critical behavior in zero magnetic field could be described as a three-dimentional long range ordering, while the fluctuations in the system are one-dimensional. In the presence of a magnetic field, the behavior of the system in the critical region of the magnetic phase diagram between the Neel temperature at zero field (3.3degK) and 1.85degK, was in good agreement with the theory. Below 1.85degK, the phase transition in a magnetic field changes into a line of triple points whose end point could be identified as a tricritical point, i.e., an intersection of three critical lines. The parameters derived from observations in the neighborhood of this tricritical point obey the scaling laws but are not in numerical agreement with theoretical predictions

Conical evaporator and liquid-return wick model for vapor anode, multi-tube AMTEC cells

Science.gov (United States)

Tournier, Jean-Michel; El-Genk, Mohamed S.

2000-01-01

A detailed, 2-D thermal-hydraulic model for conical and flat evaporators and the liquid sodium return artery in PX-type AMTEC cells was developed, which predicts incipient dryout at the evaporator wick surface. Results obtained at fixed hot and cold side temperatures showed that the flat evaporator provided a slightly lower vapor pressure, but reached the capillary limit at higher temperature. The loss of performance due to partial recondensation over up to 20% of the wick surface of the deep conical evaporators was offset by the larger surface area available for evaporation, providing a slightly higher vapor pressure. Model results matched the PX-3A cell's experimental data of electrical power output, but the predicted temperature of the cell's conical evaporator was consistently ~50 K above measurements. A preliminary analysis indicated that sodium vapor leakage in the cell (through microcracks in the BASE tubes' walls or brazes) may explain the difference between predicted and measured evaporator temperatures in PX-3A. .

Erythrocyte and platelet fatty acids in retinitis pigmentosa.

Science.gov (United States)

Stanzial, A M; Bonomi, L; Cobbe, C; Olivieri, O; Girelli, D; Trevisan, M T; Bassi, A; Ferrari, S; Corrocher, R

1991-05-01

The fatty acid composition and the glutathione-peroxidase activity (GSH-Px) of erythrocytes and platelets, the production of malondialdehyde (MDA) by platelets and the activity of the main systems of transmembrane cation transport in erythrocyte have been studied in 12 patients (5 males and 7 females) affected by retinitis pigmentosa (RP). A remarkable increase of saturated fatty acids (SFA), particularly of stearic acid (C18:0), has been noted in these patients. The reduced unsaturated/saturated fatty acids ratio (PUFA/SFA) observed in both erythrocytes and platelets and the decrease of arachidonic acid in platelets may depend by an active peroxidation process as documented by the increase of MDA. Platelet glutathione-peroxidase (PTL-GSH-PX) and plasma retinol were in the normal range, whereas erythrocyte glutathione-peroxidase (E-GSH-PX), MDA and plasma alfa-toco-pherol were increased in patients with RP. The activities of Na(+)-K+ pump, cotransport and Na(+)-Li+ countertransport were normal in RP erythrocytes.

Shock response of a gamma titanium aluminide

International Nuclear Information System (INIS)

Shazly, Mostafa; Prakash, Vikas

2008-01-01

Potential use of γ-TiAl alloys in aerospace and other structural applications require knowledge of their impact behavior for better evaluation and modeling. In the present study plate impact experiments are conducted using a single-stage gas gun to better understand the shock behavior of the recently developed class of gamma titanium aluminide alloys--the Gamma-Met PX. The Gamma-Met PX showed superior shock properties when compared to the conventional titanium aluminide alloys. The spall strength of Gamma-Met PX is 1.8±0.09 GPa, which is four to six times higher than those reported for other gamma titanium aluminide alloys. Moreover, it has a Hugoniot elastic limit of 1.88 GPa at a target thickness of 3.86 mm, which drops to 1.15 GPa at target thickness of 15.8 mm. The decay in the elastic precursor is continuous without showing an asymptote to a constant level within the range of target thicknesses studied

X-point effect on edge stability

International Nuclear Information System (INIS)

Saarelma, S; Kirk, A; Kwon, O J

2011-01-01

We study the effects of the X-point configuration on edge localized mode (ELM) triggering peeling and ballooning modes using fixed boundary equilibria and modifying the plasma shape to approach the limit of a true X-point. The current driven pure peeling modes are asymptotically stabilized by the X-point while the stabilizing effect on ballooning modes depends on the poloidal location of the X-point. The coupled peeling-ballooning modes experience the elimination of the peeling component as the X-point is introduced. This can significantly affect the edge stability diagrams used to analyse the ELM triggering mechanisms.

Optimal Point-to-Point Trajectory Tracking of Redundant Manipulators using Generalized Pattern Search

Directory of Open Access Journals (Sweden)

Thi Rein Myo

2008-11-01

Full Text Available Optimal point-to-point trajectory planning for planar redundant manipulator is considered in this study. The main objective is to minimize the sum of the position error of the end-effector at each intermediate point along the trajectory so that the end-effector can track the prescribed trajectory accurately. An algorithm combining Genetic Algorithm and Pattern Search as a Generalized Pattern Search GPS is introduced to design the optimal trajectory. To verify the proposed algorithm, simulations for a 3-D-O-F planar manipulator with different end-effector trajectories have been carried out. A comparison between the Genetic Algorithm and the Generalized Pattern Search shows that The GPS gives excellent tracking performance.

Dynamic magnetic x-points

International Nuclear Information System (INIS)

Leboeuf, J.N.; Tajima, T.; Dawson, J.M.

1981-03-01

Two-and-one-half dimensional magnetostatic and electromagnetic particle simulations of time-varying magnetic x-points and the associated plasma response are reported. The stability and topology depend on the crossing angle of the field lines at the x-point, irrespective of the plasma β. The electrostatic field and finite Larmor radius effects play an important role in current penetration and shaping of the plasma flow. The snapping of the field lines, and dragging of the plasma into, and confinement of the plasma at, an o-point (magnetic island) is observed. Magnetic island coalescence with explosive growth of the coalescence mode occurs and is accompanied by a large increase of kinetic energy and temperature as well as the formation of hot tails on the distribution functions

Distributional modeling and short-term forecasting of electricity prices by Generalized Additive Models for Location, Scale and Shape

International Nuclear Information System (INIS)

Serinaldi, Francesco

2011-01-01

In the context of the liberalized and deregulated electricity markets, price forecasting has become increasingly important for energy company's plans and market strategies. Within the class of the time series models that are used to perform price forecasting, the subclasses of methods based on stochastic time series and causal models commonly provide point forecasts, whereas the corresponding uncertainty is quantified by approximate or simulation-based confidence intervals. Aiming to improve the uncertainty assessment, this study introduces the Generalized Additive Models for Location, Scale and Shape (GAMLSS) to model the dynamically varying distribution of prices. The GAMLSS allow fitting a variety of distributions whose parameters change according to covariates via a number of linear and nonlinear relationships. In this way, price periodicities, trends and abrupt changes characterizing both the position parameter (linked to the expected value of prices), and the scale and shape parameters (related to price volatility, skewness, and kurtosis) can be explicitly incorporated in the model setup. Relying on the past behavior of the prices and exogenous variables, the GAMLSS enable the short-term (one-day ahead) forecast of the entire distribution of prices. The approach was tested on two datasets from the widely studied California Power Exchange (CalPX) market, and the less mature Italian Power Exchange (IPEX). CalPX data allow comparing the GAMLSS forecasting performance with published results obtained by different models. The study points out that the GAMLSS framework can be a flexible alternative to several linear and nonlinear stochastic models. - Research Highlights: ► Generalized Additive Models for Location, Scale and Shape (GAMLSS) are used to model electricity prices' time series. ► GAMLSS provide the entire dynamicaly varying distribution function of prices resorting to a suitable set of covariates that drive the instantaneous values of the parameters

SharePoint 2010 Development For Dummies

CERN Document Server

Withee, Ken

2011-01-01

A much-needed guide that shows you how to leverage SharePoint tools without writing a line of code!. The great news about SharePoint is…you don't need to be a seasoned .NET developer to develop custom functions for it. This book shows you how to use SharePoint Designer, Report Builder, Dashboard Designer, InfoPath, Excel, Word, Visio, and the SharePoint web-based UI to design and develop—without ever writing a line of code! Learn how to customize your site, build SharePoint apps, start social networking, or add Web parts.  This straightforward guide makes everything easier.: Introduces you to

Critical point analysis of phase envelope diagram

International Nuclear Information System (INIS)

Soetikno, Darmadi; Siagian, Ucok W. R.; Kusdiantara, Rudy; Puspita, Dila; Sidarto, Kuntjoro A.; Soewono, Edy; Gunawan, Agus Y.

2014-01-01

Phase diagram or phase envelope is a relation between temperature and pressure that shows the condition of equilibria between the different phases of chemical compounds, mixture of compounds, and solutions. Phase diagram is an important issue in chemical thermodynamics and hydrocarbon reservoir. It is very useful for process simulation, hydrocarbon reactor design, and petroleum engineering studies. It is constructed from the bubble line, dew line, and critical point. Bubble line and dew line are composed of bubble points and dew points, respectively. Bubble point is the first point at which the gas is formed when a liquid is heated. Meanwhile, dew point is the first point where the liquid is formed when the gas is cooled. Critical point is the point where all of the properties of gases and liquids are equal, such as temperature, pressure, amount of substance, and others. Critical point is very useful in fuel processing and dissolution of certain chemicals. Here in this paper, we will show the critical point analytically. Then, it will be compared with numerical calculations of Peng-Robinson equation by using Newton-Raphson method. As case studies, several hydrocarbon mixtures are simulated using by Matlab

Critical point analysis of phase envelope diagram

Energy Technology Data Exchange (ETDEWEB)

Soetikno, Darmadi; Siagian, Ucok W. R. [Department of Petroleum Engineering, Institut Teknologi Bandung, Jl. Ganesha 10, Bandung 40132 (Indonesia); Kusdiantara, Rudy, E-mail: rkusdiantara@s.itb.ac.id; Puspita, Dila, E-mail: rkusdiantara@s.itb.ac.id; Sidarto, Kuntjoro A., E-mail: rkusdiantara@s.itb.ac.id; Soewono, Edy; Gunawan, Agus Y. [Department of Mathematics, Institut Teknologi Bandung, Jl. Ganesha 10, Bandung 40132 (Indonesia)

2014-03-24

Phase diagram or phase envelope is a relation between temperature and pressure that shows the condition of equilibria between the different phases of chemical compounds, mixture of compounds, and solutions. Phase diagram is an important issue in chemical thermodynamics and hydrocarbon reservoir. It is very useful for process simulation, hydrocarbon reactor design, and petroleum engineering studies. It is constructed from the bubble line, dew line, and critical point. Bubble line and dew line are composed of bubble points and dew points, respectively. Bubble point is the first point at which the gas is formed when a liquid is heated. Meanwhile, dew point is the first point where the liquid is formed when the gas is cooled. Critical point is the point where all of the properties of gases and liquids are equal, such as temperature, pressure, amount of substance, and others. Critical point is very useful in fuel processing and dissolution of certain chemicals. Here in this paper, we will show the critical point analytically. Then, it will be compared with numerical calculations of Peng-Robinson equation by using Newton-Raphson method. As case studies, several hydrocarbon mixtures are simulated using by Matlab.

Stochastic Lanchester Air-to-Air Campaign Model: Model Description and Users Guides

Science.gov (United States)

2009-01-01

state PBW = Probability of Blue win PRW = Probability of Red win PNL = Probability of no loss Px = Probability of event x Qx = (1-Px) Probability...probabilities are PNL , PBW, and PRW.4 To infer KRR ≡ kb/kr, we may evaluate P11 as equal to PNL , and then solve [ ] [ 1111BW10 P1KRR1 KRRP1 k ] rkb kbPP...Eq. 2-10] for KRR. 4 One may choose to divide the Pd − Pk probabilities PBW, PRW, and PNL by 1

The ultimate SharePoint performance guide ! configuring SharePoint, SQL and Office 365 for maximum performance

CERN Document Server

Catrinescu, Vlad

2017-01-01

This is an ultimate guidance on performance for SharePoint Server 2013, 2016 and SharePoint Online inspired both by Microsoft’s best practices and real life experiences from countless deployments on the field.This book was Tech Reviewed by Microsoft MVP & RD Jussi Roine and includes an awesome foreword by SharePoint MVP Christian Buckley.

77 FR 14963 - Special Local Regulation; Moss Point Rockin' the Riverfront Festival; O'Leary Lake; Moss Point, MS

Science.gov (United States)

2012-03-14

...-AA08 Special Local Regulation; Moss Point Rockin' the Riverfront Festival; O'Leary Lake; Moss Point, MS..., and persons on navigable waters during the Moss Point Rockin' the Riverfront Festival high speed boat... and vessels from safety hazards associated with the Moss Point Rockin' the Riverfront Festival high...

Interest point detection for hyperspectral imagery

Science.gov (United States)

Dorado-Muñoz, Leidy P.; Vélez-Reyes, Miguel; Roysam, Badrinath; Mukherjee, Amit

2009-05-01

This paper presents an algorithm for automated extraction of interest points (IPs)in multispectral and hyperspectral images. Interest points are features of the image that capture information from its neighbours and they are distinctive and stable under transformations such as translation and rotation. Interest-point operators for monochromatic images were proposed more than a decade ago and have since been studied extensively. IPs have been applied to diverse problems in computer vision, including image matching, recognition, registration, 3D reconstruction, change detection, and content-based image retrieval. Interest points are helpful in data reduction, and reduce the computational burden of various algorithms (like registration, object detection, 3D reconstruction etc) by replacing an exhaustive search over the entire image domain by a probe into a concise set of highly informative points. An interest operator seeks out points in an image that are structurally distinct, invariant to imaging conditions, stable under geometric transformation, and interpretable which are good candidates for interest points. Our approach extends ideas from Lowe's keypoint operator that uses local extrema of Difference of Gaussian (DoG) operator at multiple scales to detect interest point in gray level images. The proposed approach extends Lowe's method by direct conversion of scalar operations such as scale-space generation, and extreme point detection into operations that take the vector nature of the image into consideration. Experimental results with RGB and hyperspectral images which demonstrate the potential of the method for this application and the potential improvements of a fully vectorial approach over band-by-band approaches described in the literature.

On the influence of extrinsic point defects on irradiation-induced point-defect distributions in silicon

International Nuclear Information System (INIS)

Vanhellemont, J.; Romano-Rodriguez, A.

1994-01-01

A semi-quantitative model describing the influence of interfaces and stress fields on {113}-defect generation in silicon during 1-MeV electron irradiation, is further developed to take into account also the role of extrinsic point defects. It is shown that the observed distribution of {113}-defects in high-flux electron-irradiated silicon and its dependence on irradiation temperature and dopant concentration can be understood by taking into account not only the influence of the surfaces and interfaces as sinks for intrinsic point defects but also the thermal stability of the bulk sinks for intrinsic point defects. In heavily doped silicon the bulk sinks are related with pairing reactions of the dopant atoms with the generated intrinsic point defects or related with enhanced recombination of vacancies and self-interstitials at extrinsic point defects. The obtained theoretical results are correlated with published experimental data on boron-and phosphorus-doped silicon and are illustrated with observations obtained by irradiating cross-section transmission electron microscopy samples of wafer with highly doped surface layers. (orig.)

MOVING WINDOW SEGMENTATION FRAMEWORK FOR POINT CLOUDS

Directory of Open Access Journals (Sweden)

G. Sithole

2012-07-01

Full Text Available As lidar point clouds become larger streamed processing becomes more attractive. This paper presents a framework for the streamed segmentation of point clouds with the intention of segmenting unstructured point clouds in real-time. The framework is composed of two main components. The first component segments points within a window shifting over the point cloud. The second component stitches the segments within the windows together. In this fashion a point cloud can be streamed through these two components in sequence, thus producing a segmentation. The algorithm has been tested on airborne lidar point cloud and some results of the performance of the framework are presented.

Equipartitioning and balancing points of polygons

Directory of Open Access Journals (Sweden)

Shunmugam Pillay

2010-07-01

Full Text Available The centre of mass G of a triangle has the property that the rays to the vertices from G sweep out triangles having equal areas. We show that such points, termed equipartitioning points in this paper, need not exist in other polygons. A necessary and sufficient condition for a quadrilateral to have an equipartitioning point is that one of its diagonals bisects the other. The general theorem, namely, necessary and sufficient conditions for equipartitioning points for arbitrary polygons to exist, is also stated and proved. When this happens, they are in general, distinct from the centre of mass. In parallelograms, and only in them, do the two points coincide.

Seeing your error alters my pointing: observing systematic pointing errors induces sensori-motor after-effects.

Directory of Open Access Journals (Sweden)

Roberta Ronchi

Full Text Available During the procedure of prism adaptation, subjects execute pointing movements to visual targets under a lateral optical displacement: as consequence of the discrepancy between visual and proprioceptive inputs, their visuo-motor activity is characterized by pointing errors. The perception of such final errors triggers error-correction processes that eventually result into sensori-motor compensation, opposite to the prismatic displacement (i.e., after-effects. Here we tested whether the mere observation of erroneous pointing movements, similar to those executed during prism adaptation, is sufficient to produce adaptation-like after-effects. Neurotypical participants observed, from a first-person perspective, the examiner's arm making incorrect pointing movements that systematically overshot visual targets location to the right, thus simulating a rightward optical deviation. Three classical after-effect measures (proprioceptive, visual and visual-proprioceptive shift were recorded before and after first-person's perspective observation of pointing errors. Results showed that mere visual exposure to an arm that systematically points on the right-side of a target (i.e., without error correction produces a leftward after-effect, which mostly affects the observer's proprioceptive estimation of her body midline. In addition, being exposed to such a constant visual error induced in the observer the illusion "to feel" the seen movement. These findings indicate that it is possible to elicit sensori-motor after-effects by mere observation of movement errors.

NOTE: Do acupuncture points exist?

Science.gov (United States)

Yan, Xiaohui; Zhang, Xinyi; Liu, Chenglin; Dang, Ruishan; Huang, Yuying; He, Wei; Ding, Guanghong

2009-05-01

We used synchrotron x-ray fluorescence analysis to probe the distribution of four chemical elements in and around acupuncture points, two located in the forearm and two in the lower leg. Three of the four acupuncture points showed significantly elevated concentrations of elements Ca, Fe, Cu and Zn in relation to levels in the surrounding tissue, with similar elevation ratios for Cu and Fe. The mapped distribution of these elements implies that each acupuncture point seems to be elliptical with the long axis along the meridian.

Detecting Change-Point via Saddlepoint Approximations

Institute of Scientific and Technical Information of China (English)

Zhaoyuan LI; Maozai TIAN

2017-01-01

It's well-known that change-point problem is an important part of model statistical analysis.Most of the existing methods are not robust to criteria of the evaluation of change-point problem.In this article,we consider "mean-shift" problem in change-point studies.A quantile test of single quantile is proposed based on saddlepoint approximation method.In order to utilize the information at different quantile of the sequence,we further construct a "composite quantile test" to calculate the probability of every location of the sequence to be a change-point.The location of change-point can be pinpointed rather than estimated within a interval.The proposed tests make no assumptions about the functional forms of the sequence distribution and work sensitively on both large and small size samples,the case of change-point in the tails,and multiple change-points situation.The good performances of the tests are confirmed by simulations and real data analysis.The saddlepoint approximation based distribution of the test statistic that is developed in the paper is of independent interest and appealing.This finding may be of independent interest to the readers in this research area.

Residual analysis for spatial point processes

DEFF Research Database (Denmark)

Baddeley, A.; Turner, R.; Møller, Jesper

We define residuals for point process models fitted to spatial point pattern data, and propose diagnostic plots based on these residuals. The techniques apply to any Gibbs point process model, which may exhibit spatial heterogeneity, interpoint interaction and dependence on spatial covariates. Ou...... or covariate effects. Q-Q plots of the residuals are effective in diagnosing interpoint interaction. Some existing ad hoc statistics of point patterns (quadrat counts, scan statistic, kernel smoothed intensity, Berman's diagnostic) are recovered as special cases....

Determine point-to-point networking interactions using regular expressions

Directory of Open Access Journals (Sweden)

Konstantin S. Deev

2015-06-01

Full Text Available As Internet growth and becoming more popular, the number of concurrent data flows start to increasing, which makes sense in bandwidth requested. Providers and corporate customers need ability to identify point-to-point interactions. The best is to use special software and hardware implementations that distribute the load in the internals of the complex, using the principles and approaches, in particular, described in this paper. This paper represent the principles of building system, which searches for a regular expression match using computing on graphics adapter in server station. A significant computing power and capability to parallel execution on modern graphic processor allows inspection of large amounts of data through sets of rules. Using the specified characteristics can lead to increased computing power in 30…40 times compared to the same setups on the central processing unit. The potential increase in bandwidth capacity could be used in systems that provide packet analysis, firewalls and network anomaly detectors.

Effects of chestnut tannins on performance and antioxidative status of transition dairy cows.

Science.gov (United States)

Liu, H W; Zhou, D W; Li, K

2013-09-01

This study was conducted to evaluate the effects of chestnut tannins (CT) on performance and antioxidative status of transition dairy cows. Twenty multiparous Chinese Holstein cows in late gestation were paired according to expected calving date and randomly assigned either to a diet supplemented with CT (CNT, 10 g of CT/kg of diet, dry matter basis) or to an unsupplemented control (CON) diet from 3 wk prepartum to 3 wk postpartum. Blood samples were taken on d -21, 1, 7, and 21 relative to calving for analysis of superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), total antioxidant capacity (T-AOC), and malondialdehyde (MDA). Liver samples were taken by puncture biopsy on d 1 and 21 relative to calving for analysis of SOD, GSH-Px, and MDA. Data were analyzed for a completely randomized block design with repeated measures. The addition of CT had no significant effects on dry matter intake, body weight, body condition score, milk yield, 3.5% fat-corrected milk yield, and milk composition but did decrease milk MDA and somatic cell score in transition dairy cows. Dry matter intake decreased from d -21 to 0 and increased from d 1 to 21 relative to calving across treatments. During the experimental period, body weight and body condition score decreased, whereas milk MDA and somatic cell score increased across treatments. A time effect was also observed for plasma MDA, which peaked on d 1 relative to calving and remained higher than that on d -21 relative to calving across treatments. Addition of CT decreased MDA concentrations in plasma and liver. Neither time nor CT × time effects were observed for SOD and T-AOC in plasma and SOD and GSH-Px in liver; a time effect was observed for plasma GSH-Px, which peaked on d 1 relative to calving and remained higher than those on d -21 relative to calving across treatments. Addition of CT increased SOD, GSH-Px, and T-AOC activities in plasma and SOD and GSH-Px activities in liver. In conclusion, addition of CT might

Implementation of Steiner point of fuzzy set.

Science.gov (United States)

Liang, Jiuzhen; Wang, Dejiang

2014-01-01

This paper deals with the implementation of Steiner point of fuzzy set. Some definitions and properties of Steiner point are investigated and extended to fuzzy set. This paper focuses on establishing efficient methods to compute Steiner point of fuzzy set. Two strategies of computing Steiner point of fuzzy set are proposed. One is called linear combination of Steiner points computed by a series of crisp α-cut sets of the fuzzy set. The other is an approximate method, which is trying to find the optimal α-cut set approaching the fuzzy set. Stability analysis of Steiner point of fuzzy set is also studied. Some experiments on image processing are given, in which the two methods are applied for implementing Steiner point of fuzzy image, and both strategies show their own advantages in computing Steiner point of fuzzy set.

A specific glycerol kinase induces rapid cold hardening of the diamondback moth, Plutella xylostella.

Science.gov (United States)

Park, Youngjin; Kim, Yonggyun

2014-08-01

Insects in temperate zones survive low temperatures by migrating or tolerating the cold. The diamondback moth, Plutella xylostella, is a serious insect pest on cabbage and other cruciferous crops worldwide. We showed that P. xylostella became cold-tolerant by expressing rapid cold hardiness (RCH) in response to a brief exposure to moderately low temperature (4°C) for 7h along with glycerol accumulation in hemolymph. Glycerol played a crucial role in the cold-hardening process because exogenously supplying glycerol significantly increased the cold tolerance of P. xylostella larvae without cold acclimation. To determine the genetic factor(s) responsible for RCH and the increase of glycerol, four glycerol kinases (GKs), and glycerol-3-phosphate dehydrogenase (PxGPDH) were predicted from the whole P. xylostella genome and analyzed for their function associated with glycerol biosynthesis. All predicted genes were expressed, but differed in their expression during different developmental stages and in different tissues. Expression of the predicted genes was individually suppressed by RNA interference (RNAi) using double-stranded RNAs specific to target genes. RNAi of PxGPDH expression significantly suppressed RCH and glycerol accumulation. Only PxGK1 among the four GKs was responsible for RCH and glycerol accumulation. Furthermore, PxGK1 expression was significantly enhanced during RCH. These results indicate that a specific GK, the terminal enzyme to produce glycerol, is specifically inducible during RCH to accumulate the main cryoprotectant. Copyright © 2014 Elsevier Ltd. All rights reserved.

Multi-objective optimization of p-xylene oxidation process using an improved self-adaptive differential evolution algorithm

Institute of Scientific and Technical Information of China (English)

Lili Tao; Bin Xu; Zhihua Hu; Weimin Zhong

2017-01-01

The rise in the use of global polyester fiber contributed to strong demand of the Terephthalic acid (TPA). The liquid-phase catalytic oxidation of p-xylene (PX) to TPA is regarded as a critical and efficient chemical process in industry [1]. PX oxidation reaction involves many complex side reactions, among which acetic acid combustion and PX combustion are the most important. As the target product of this oxidation process, the quality and yield of TPA are of great concern. However, the improvement of the qualified product yield can bring about the high energy consumption, which means that the economic objectives of this process cannot be achieved simulta-neously because the two objectives are in conflict with each other. In this paper, an improved self-adaptive multi-objective differential evolution algorithm was proposed to handle the multi-objective optimization prob-lems. The immune concept is introduced to the self-adaptive multi-objective differential evolution algorithm (SADE) to strengthen the local search ability and optimization accuracy. The proposed algorithm is successfully tested on several benchmark test problems, and the performance measures such as convergence and divergence metrics are calculated. Subsequently, the multi-objective optimization of an industrial PX oxidation process is carried out using the proposed immune self-adaptive multi-objective differential evolution algorithm (ISADE). Optimization results indicate that application of ISADE can greatly improve the yield of TPA with low combustion loss without degenerating TA quality.

Nerve supply to the internal anal sphincter differs from that to the distal rectum: an immunohistochemical study of cadavers.

Science.gov (United States)

Kinugasa, Yusuke; Arakawa, Takashi; Murakami, Gen; Fujimiya, Mineko; Sugihara, Kenichi

2014-04-01

Fecal incontinence is a common problem after anal sphincter-preserving operations. The intersphincteric autonomic nerves supplying the internal anal sphincter (IAS) are formed by the union of: (1) nerve fibers from Auerbach's nerve plexus of the most distal part of the rectum and (2) the inferior rectal branches of the pelvic plexus (IRB-PX) running along the conjoint longitudinal muscle coat. The aim of the present study is to identify the detailed morphology of nerves to the IAS. The study comprised histological and immunohistochemical evaluations of paraffin-embedded sections from a large block of anal canal from the preserved 10 cadavers. The IRB-PX came from the superior aspect of the levator ani and ran into the anal canal on the anterolateral side. These nerves contained both sympathetic and parasympathetic fibers, but the sympathetic content was much higher than in nerves from the distal rectum. All intramural ganglion cells in the distal rectum were neuronal nitric oxide synthase-positive and tyrosine hydroxylase-negative and were restricted to above the squamous-columnar epithelial junction. Parasympathetic nerves formed a lattice-like plexus in the circular smooth muscles of the distal rectum, whereas the IAS contained short, longitudinally running sympathetic and parasympathetic nerves, although sympathetic nerves were dominant. The major autonomic nerve input to the IAS seemed not to originate from the distal rectum but from the IRB-PX. Injury to the IRB-PX during surgery seemed to result in loss of innervation to the major part of the IAS.

Parametric statistical change point analysis

CERN Document Server

Chen, Jie

2000-01-01

This work is an in-depth study of the change point problem from a general point of view and a further examination of change point analysis of the most commonly used statistical models Change point problems are encountered in such disciplines as economics, finance, medicine, psychology, signal processing, and geology, to mention only several The exposition is clear and systematic, with a great deal of introductory material included Different models are presented in each chapter, including gamma and exponential models, rarely examined thus far in the literature Other models covered in detail are the multivariate normal, univariate normal, regression, and discrete models Extensive examples throughout the text emphasize key concepts and different methodologies are used, namely the likelihood ratio criterion, and the Bayesian and information criterion approaches A comprehensive bibliography and two indices complete the study

Mastering Microsoft SharePoint Foundation 2010

CERN Document Server

Callahan, C A

2011-01-01

Everything IT professionals need to create collaborative solutions. SharePoint Foundation 2010 is the newest version of a powerful collaboration tool used in many Exchange-enabled organizations. This book gets network professionals and business application administrators up to speed on the updates, features, and installation procedures, preparing them to create powerful collaboration structures for their companies.: Microsoft SharePoint Foundation 2010 is the successor to Windows SharePoint Services 3.0 and is used with Microsoft Office SharePoint Server to enable collaboration; this guide pre

Review of NJ point system.

Science.gov (United States)

2013-03-01

The purpose of this study is to investigate the comparative effectiveness of point-based versus incident-based : negligent driver monitoring systems and to explore how certain changes to the existing point-based system used in : New Jersey might impr...

Comprehensive Interpretation of a Three-Point Gauss Quadrature with Variable Sampling Points and Its Application to Integration for Discrete Data

Directory of Open Access Journals (Sweden)

Young-Doo Kwon

2013-01-01

Full Text Available This study examined the characteristics of a variable three-point Gauss quadrature using a variable set of weighting factors and corresponding optimal sampling points. The major findings were as follows. The one-point, two-point, and three-point Gauss quadratures that adopt the Legendre sampling points and the well-known Simpson’s 1/3 rule were found to be special cases of the variable three-point Gauss quadrature. In addition, the three-point Gauss quadrature may have out-of-domain sampling points beyond the domain end points. By applying the quadratically extrapolated integrals and nonlinearity index, the accuracy of the integration could be increased significantly for evenly acquired data, which is popular with modern sophisticated digital data acquisition systems, without using higher-order extrapolation polynomials.

Effect of Antenna Pointing Errors on SAR Imaging Considering the Change of the Point Target Location

Science.gov (United States)

Zhang, Xin; Liu, Shijie; Yu, Haifeng; Tong, Xiaohua; Huang, Guoman

2018-04-01

Towards spaceborne spotlight SAR, the antenna is regulated by the SAR system with specific regularity, so the shaking of the internal mechanism is inevitable. Moreover, external environment also has an effect on the stability of SAR platform. Both of them will cause the jitter of the SAR platform attitude. The platform attitude instability will introduce antenna pointing error on both the azimuth and range directions, and influence the acquisition of SAR original data and ultimate imaging quality. In this paper, the relations between the antenna pointing errors and the three-axis attitude errors are deduced, then the relations between spaceborne spotlight SAR imaging of the point target and antenna pointing errors are analysed based on the paired echo theory, meanwhile, the change of the azimuth antenna gain is considered as the spotlight SAR platform moves ahead. The simulation experiments manifest the effects on spotlight SAR imaging caused by antenna pointing errors are related to the target location, that is, the pointing errors of the antenna beam will severely influence the area far away from the scene centre of azimuth direction in the illuminated scene.

'Saddle-point' ionization

International Nuclear Information System (INIS)

Gay, T.J.; Hale, E.B.; Irby, V.D.; Olson, R.E.; Missouri Univ., Rolla; Berry, H.G.

1988-01-01

We have studied the ionization of rare gases by protons at intermediate energies, i.e., energies at which the velocities of the proton and the target-gas valence electrons are comparable. A significant channel for electron production in the forward direction is shown to be 'saddle-point' ionization, in which electrons are stranded on or near the saddle-point of electric potential between the receding projectile and the ionized target. Such electrons yield characteristic energy spectra, and contribute significantly to forward-electron-production cross sections. Classical trajectory Monte Carlo calculations are found to provide qualitative agreement with our measurements and the earlier measurements of Rudd and coworkers, and reproduce, in detail, the features of the general ionization spectra. (orig.)

Unconventional Quantum Critical Points

OpenAIRE

Xu, Cenke

2012-01-01

In this paper we review the theory of unconventional quantum critical points that are beyond the Landau's paradigm. Three types of unconventional quantum critical points will be discussed: (1). The transition between topological order and semiclassical spin ordered phase; (2). The transition between topological order and valence bond solid phase; (3). The direct second order transition between different competing orders. We focus on the field theory and universality class of these unconventio...

Implementing floating-point DSP

Czech Academy of Sciences Publication Activity Database

Kadlec, Jiří; Chappel, S.

2006-01-01

Roč. 2, č. 3 (2006), s. 12-14 R&D Projects: GA AV ČR 1ET400750406; GA MŠk 1M0567 EU Projects: European Commission(XE) 027611 - AETHER Program:FP6 Institutional research plan: CEZ:AV0Z10750506 Keywords : PicoBlaze * floating point * FPGA Subject RIV: JC - Computer Hardware ; Software http://www.xilinx.com/publications/ magazines /emb_03/xc_pdf/p12-14_3emb-point.pdf

SharePoint User's Guide

CERN Document Server

Corporation, Infusion Development

2009-01-01

This straightforward guide shows SharePoint users how to create and use web sites for sharing and collaboration. Learn to use the document and picture libraries for adding and editing content, add discussion boards and surveys, receive alerts when documents and information have been added or changed, and enhance security. Designed to help you find answers quickly, the book shows how to make the most of SharePoint for productivity and collaboration.

SharePoint Server 2010 Enterprise Content Management

CERN Document Server

Kitta, Todd; Caplinger, Chris; Houberg, Russ

2011-01-01

SharePoint experts focus on SharePoint 2010 as a platform for Enterprise Content Management SharePoint allows all users in an organization to manage and share their content reliably and securely. If you're interested in building Web sites using the new capabilities of enterprise content management (ECM) in SharePoint 2010, then this book is for you. You'll discover how SharePoint 2010 spans rich document management, records management, business process management and web content management in a seamless way to manage and share content. The team of SharePoint experts discusses the ECM capabi

How PowerPoint Is Killing Education

Science.gov (United States)

Isseks, Marc

2011-01-01

Although it is essential to incorporate new technologies into the classroom, says Isseks, one trend has negatively affected instruction--the misuse of PowerPoint presentations. The author describes how poorly designed PowerPoint presentations reduce complex thoughts to bullet points and reduce the act of learning to transferring text from slide to…

Making SharePoint® Chemically Aware™.

Science.gov (United States)

Tallapragada, Kartik; Chewning, Joseph; Kombo, David; Ludwick, Beverly

2012-01-12

The use of SharePoint® collaboration software for content management has become a critical part of today's drug discovery process. SharePoint 2010 software has laid a foundation which enables researchers to collaborate and search on various contents. The amount of data generated during a transition of a single compound from preclinical discovery to commercialization can easily range in terabytes, thus there is a greater demand of a chemically aware search algorithm that supplements SharePoint which enables researchers to query for information in a more intuitive and effective way. Thus by supplementing SharePoint with Chemically Aware™ features provides a great value to the pharmaceutical and biotech companies and makes drug discovery more efficient. Using several tools we have integrated SharePoint with chemical, compound, and reaction databases, thereby improving the traditional search engine capability and enhancing the user experience. This paper describes the implementation of a Chemically Aware™ system to supplement SharePoint. A Chemically Aware SharePoint (CASP) allows users to tag documents by drawing a structure and associating it with the related content. It also allows the user to search SharePoint software content and internal/external databases by carrying out substructure, similarity, SMILES, and IUPAC name searches. Building on traditional search, CASP takes SharePoint one step further by providing a intuitive GUI to the researchers to base their search on their knowledge of chemistry than textual search. CASP also provides a way to integrate with other systems, for example a researcher can perform a sub-structure search on pdf documents with embedded molecular entities. A Chemically Aware™ system supplementing SharePoint is a step towards making drug discovery process more efficient and also helps researchers to search for information in a more intuitive way. It also helps the researchers to find information which was once difficult to find

Making SharePoint® Chemically Aware™

Directory of Open Access Journals (Sweden)

Tallapragada Kartik

2012-01-01

Full Text Available Abstract Background The use of SharePoint® collaboration software for content management has become a critical part of today's drug discovery process. SharePoint 2010 software has laid a foundation which enables researchers to collaborate and search on various contents. The amount of data generated during a transition of a single compound from preclinical discovery to commercialization can easily range in terabytes, thus there is a greater demand of a chemically aware search algorithm that supplements SharePoint which enables researchers to query for information in a more intuitive and effective way. Thus by supplementing SharePoint with Chemically Aware™ features provides a great value to the pharmaceutical and biotech companies and makes drug discovery more efficient. Using several tools we have integrated SharePoint with chemical, compound, and reaction databases, thereby improving the traditional search engine capability and enhancing the user experience. Results This paper describes the implementation of a Chemically Aware™ system to supplement SharePoint. A Chemically Aware SharePoint (CASP allows users to tag documents by drawing a structure and associating it with the related content. It also allows the user to search SharePoint software content and internal/external databases by carrying out substructure, similarity, SMILES, and IUPAC name searches. Building on traditional search, CASP takes SharePoint one step further by providing a intuitive GUI to the researchers to base their search on their knowledge of chemistry than textual search. CASP also provides a way to integrate with other systems, for example a researcher can perform a sub-structure search on pdf documents with embedded molecular entities. Conclusion A Chemically Aware™ system supplementing SharePoint is a step towards making drug discovery process more efficient and also helps researchers to search for information in a more intuitive way. It also helps the

Rayleigh-Love model of longitudinal vibrations of conical and exponential rods: Exact solutions and numerical simulation by the method of lines

CSIR Research Space (South Africa)

Shatalov, M

2011-07-01

Full Text Available of conical surface of the rod is described by equation ( ) ( )pr x k x x kx= ? = , where px is coordinate of the pole of the cone, px x x= ? , then ( ) 2 2S x k xpi= , ( ) 4 4 2pI x k xpi= and equation (2) is rewritten as follows: ( ) ( ) ( ) ( ) ( ) 2... rod in accordance with the classi- cal theory, and 2 k c ? ?? = is the wavenumber of the conical rod which has dimension 1m? . Introducing new dimensionless variable z x?= , considering new function ( ) zV z U ? ? ? = ? ?? ? ( )W z z...

The Tipping Points of Technology Development

Directory of Open Access Journals (Sweden)

Tauno Kekäle

2014-07-01

Full Text Available The tipping point, the decisive point in time in the competition between old and new, is an interesting phenomenon in physics of today. This aspect in technology acceptance is connected to many business decisions such as technology investments, product releases, resource allocation, sales forecasts and, ultimately, affects the profitability and even survival of a company. The tipping point itself is based on many stochastic and dynamic variables, and the process may at least partly be described as path-dependent. This paper analyses the tipping point from three aspects: (1 product performance, (2 features of the market and infrastructure (including related technologies and human network externalities, and (3 actions of the incumbents (including customer lock-in, systems lock-in, and sustaining innovation. The paper is based on the Bass s-curve idea and the technology trajectory concept proposed by Dosi. Three illustrative cases are presented to make the point of the multiple factors affecting technology acceptance and, thus, the tipping point. The paper also suggests outlines for further research in field of computer simulation.

PowerPoint 2013 for dummies

CERN Document Server

Lowe, Doug

2013-01-01

Get up and running with this full-color guide to PowerPoint 2013! PowerPoint, the number one presentation software, has been revised and improved with the introduction of Microsoft Office 2013. With this all-new, full-color book by your side, you will learn how to take full advantage of all of PowerPoint's powerful and dynamic capabilities. Bestselling veteran For Dummies, author Doug Lowe breaks it all down so that you can create a powerful and effective slideshow presentation with the new wide-screen theme and variant that incorporates videos, pictures, and shapes, and all

Generation of a statistical shape model with probabilistic point correspondences and the expectation maximization- iterative closest point algorithm

International Nuclear Information System (INIS)

Hufnagel, Heike; Pennec, Xavier; Ayache, Nicholas; Ehrhardt, Jan; Handels, Heinz

2008-01-01

Identification of point correspondences between shapes is required for statistical analysis of organ shapes differences. Since manual identification of landmarks is not a feasible option in 3D, several methods were developed to automatically find one-to-one correspondences on shape surfaces. For unstructured point sets, however, one-to-one correspondences do not exist but correspondence probabilities can be determined. A method was developed to compute a statistical shape model based on shapes which are represented by unstructured point sets with arbitrary point numbers. A fundamental problem when computing statistical shape models is the determination of correspondences between the points of the shape observations of the training data set. In the absence of landmarks, exact correspondences can only be determined between continuous surfaces, not between unstructured point sets. To overcome this problem, we introduce correspondence probabilities instead of exact correspondences. The correspondence probabilities are found by aligning the observation shapes with the affine expectation maximization-iterative closest points (EM-ICP) registration algorithm. In a second step, the correspondence probabilities are used as input to compute a mean shape (represented once again by an unstructured point set). Both steps are unified in a single optimization criterion which depe nds on the two parameters 'registration transformation' and 'mean shape'. In a last step, a variability model which best represents the variability in the training data set is computed. Experiments on synthetic data sets and in vivo brain structure data sets (MRI) are then designed to evaluate the performance of our algorithm. The new method was applied to brain MRI data sets, and the estimated point correspondences were compared to a statistical shape model built on exact correspondences. Based on established measures of ''generalization ability'' and ''specificity'', the estimates were very satisfactory

Inhomogeneous Markov point processes by transformation

DEFF Research Database (Denmark)

Jensen, Eva B. Vedel; Nielsen, Linda Stougaard

2000-01-01

We construct parametrized models for point processes, allowing for both inhomogeneity and interaction. The inhomogeneity is obtained by applying parametrized transformations to homogeneous Markov point processes. An interesting model class, which can be constructed by this transformation approach......, is that of exponential inhomogeneous Markov point processes. Statistical inference For such processes is discussed in some detail....

Effects of dietary [alpha]-tocopherol and [beta]-carotene on lipid peroxidation induced by methyl mercuric chloride in mice

Energy Technology Data Exchange (ETDEWEB)

Raun Andersen, H; Andersen, O [Department of Environmental Medicine, University of Odense, Odense (Denmark)

1993-01-01

Exposure of male CBA mice to methyl mercuric chloride, CH[sub 3]HgCl, (10-40 mg/l in drinking water) for 2 weeks resulted in dose-related Hg deposition and enhanced lipid peroxidation in liver, kidney and brain. Mice were fed well-defined semisynthetic diets containing different levels of [alpha]-tocopherol (10, 100 or 1000 mg/kg) or [beta]-carotene (1000, 10,000 or 100,000 IU/kg) for four weeks, two groups on each diet. The concentration of [alpha]-tocopherol and [beta]-carotene used corresponded to deficient, normal and high levels. During the last two weeks, one group on each diet was given 40 mg CH[sub 3]HgCl/l of drinking water. High dietary [alpha]-tocopherol protected against CH[sub 3]HgCl induced hepatic lipid peroxidation, whereas the [alpha]-tocopherol deficient diet further enhanced CH[sub 3]HgCl induced hepatic lipid peroxidation. Similar, though statistically non-significant effects occurred in the kidneys, [alpha]-tocopherol did not protect against CH[sub 3]HgCl induced lipid peroxidation in the brain. Excess dietary [beta]-carotene further enhanced CH[sub 3]HgCl induced lipid peroxidation in liver, kidney and brain. CH[sub 3]HgCl significantly decreased the activity of total glutathione peroxidase (T-GSH-Px) and Se-dependent glutathione peroxidase (Se-GSH-Px) in the kidneys in all dietary groups. High dietary [alpha]-tocopherol enhanced the activity of Se-GSH-Px in liver and kidney compared to the activity in mice fed the normal level of [alpha]-tocopherol. This occurred in mice exposed to CH[sub 3]-HgCl as well as in unexposed mice, and the difference between CH[sub 3]HgCl exposed and unexposed mice was not diminished. High dietary [alpha]-tocopherol increased the activity of both Se-GSH-Px and T-GSH-Px in the brain of CH[sub 3]HgCl-exposed mice. The dietary level of [beta]-carotene did not affect the activity of the two enzymes in the organs investigated. (au) (43 refs.).

Effects of dietary α-tocopherol and β-carotene on lipid peroxidation induced by methyl mercuric chloride in mice

International Nuclear Information System (INIS)

Raun Andersen, H.; Andersen, O.

1993-01-01

Exposure of male CBA mice to methyl mercuric chloride, CH 3 HgCl, (10-40 mg/l in drinking water) for 2 weeks resulted in dose-related Hg deposition and enhanced lipid peroxidation in liver, kidney and brain. Mice were fed well-defined semisynthetic diets containing different levels of α-tocopherol (10, 100 or 1000 mg/kg) or β-carotene (1000, 10,000 or 100,000 IU/kg) for four weeks, two groups on each diet. The concentration of α-tocopherol and β-carotene used corresponded to deficient, normal and high levels. During the last two weeks, one group on each diet was given 40 mg CH 3 HgCl/l of drinking water. High dietary α-tocopherol protected against CH 3 HgCl induced hepatic lipid peroxidation, whereas the α-tocopherol deficient diet further enhanced CH 3 HgCl induced hepatic lipid peroxidation. Similar, though statistically non-significant effects occurred in the kidneys, α-tocopherol did not protect against CH 3 HgCl induced lipid peroxidation in the brain. Excess dietary β-carotene further enhanced CH 3 HgCl induced lipid peroxidation in liver, kidney and brain. CH 3 HgCl significantly decreased the activity of total glutathione peroxidase (T-GSH-Px) and Se-dependent glutathione peroxidase (Se-GSH-Px) in the kidneys in all dietary groups. High dietary α-tocopherol enhanced the activity of Se-GSH-Px in liver and kidney compared to the activity in mice fed the normal level of α-tocopherol. This occurred in mice exposed to CH 3 -HgCl as well as in unexposed mice, and the difference between CH 3 HgCl exposed and unexposed mice was not diminished. High dietary α-tocopherol increased the activity of both Se-GSH-Px and T-GSH-Px in the brain of CH 3 HgCl-exposed mice. The dietary level of β-carotene did not affect the activity of the two enzymes in the organs investigated. (au) (43 refs.)

Trifocal intraocular lenses: a comparison of the visual performance and quality of vision provided by two different lens designs

Directory of Open Access Journals (Sweden)

Gundersen KG

2017-06-01

Full Text Available Kjell G Gundersen,1 Rick Potvin2 1IFocus Øyeklinikk AS, Haugesund, Norway; 2Science in Vision, Akron, NY, USA Purpose: To compare two different diffractive trifocal intraocular lens (IOL designs, evaluating longer-term refractive outcomes, visual acuity (VA at various distances, low contrast VA and quality of vision.Patients and methods: Patients with binocularly implanted trifocal IOLs of two different designs (FineVision [FV] and Panoptix [PX] were evaluated 6 months to 2 years after surgery. Best distance-corrected and uncorrected VA were tested at distance (4 m, intermediate (80 and 60 cm and near (40 cm. A binocular defocus curve was collected with the subject’s best distance correction in place. The preferred reading distance was determined along with the VA at that distance. Low contrast VA at distance was also measured. Quality of vision was measured with the National Eye Institute Visual Function Questionnaire near subset and the Quality of Vision questionnaire.Results: Thirty subjects in each group were successfully recruited. The binocular defocus curves differed only at vergences of −1.0 D (FV better, P=0.02, −1.5 and −2.00 D (PX better, P<0.01 for both. Best distance-corrected and uncorrected binocular vision were significantly better for the PX lens at 60 cm (P<0.01 with no significant differences at other distances. The preferred reading distance was between 42 and 43 cm for both lenses, with the VA at the preferred reading distance slightly better with the PX lens (P=0.04. There were no statistically significant differences by lens for low contrast VA (P=0.1 or for quality of vision measures (P>0.3.Conclusion: Both trifocal lenses provided excellent distance, intermediate and near vision, but several measures indicated that the PX lens provided better intermediate vision at 60 cm. This may be important to users of tablets and other handheld devices. Quality of vision appeared similar between the two lens designs

Snacks containing whey protein and polydextrose induce a sustained reduction in daily energy intake over 2 wk under free-living conditions.

Science.gov (United States)

Astbury, Nerys M; Taylor, Moira A; French, Stephen J; Macdonald, Ian A

2014-05-01

The manipulation of the composition of foods consumed as between-meal snacks may aid daily energy restriction. We compared the effects of the consumption of 2 energy-matched snack bars on appetite, energy intake (EI), and metabolic and endocrine responses. In addition, we investigated whether the acute effects of the consumption of snacks were maintained under free-living conditions and whether the habitual daily consumption of the snack over 14 d influenced these effects. Ten lean men [mean ± SD age: 30.7 ± 9.7 y; body mass index (in kg/m(2)): 23.2 ± 2.8] consumed a whey protein and polydextrose (PPX) snack bar or an isoenergetic control snack bar as a midmorning, between-meal snack for 14 consecutive days in a double-blind, randomized, crossover design. The two 14-d intervention phases were separated by a 14-d washout period. On the first (day 1) and last (day 15) days of each intervention phase, appetite, food intake, and blood metabolite and endocrine responses were assessed under laboratory conditions. Free-living EI was recorded on days 4, 8, and 12 of interventions. Total daily EI was significantly lower when the PPX snack was consumed during experimental days (10,149 ± 831 compared with 11,931 ± 896 kJ; P snack was consumed during the free-living part of the intervention (7904 ± 610 compared with 9041 ± 928 kJ; P snack was associated with lower glucose and ghrelin and higher glucagon-like peptide 1 and peptide tyrosine-tyrosine responses. The manipulation of the composition of foods consumed as snacks is an effective way to limit subsequent EI. This trial was registered at clinicaltrials.gov as NCT01927926.

Influence of CeO{sub 2} NPs on biological phosphorus removal and bacterial community shifts in a sequencing batch biofilm reactor with the differential effects of molecular oxygen

Energy Technology Data Exchange (ETDEWEB)

Xu, Yi; Wang, Chao [Key Laboratory of Integrated Regulation and Resources Development on Shallow Lakes, Ministry of Education, Hohai University, Nanjing 210098 (China); College of Environment, Hohai University, Nanjing 210098 (China); Hou, Jun, E-mail: hhuhjyhj@126.com [Key Laboratory of Integrated Regulation and Resources Development on Shallow Lakes, Ministry of Education, Hohai University, Nanjing 210098 (China); College of Environment, Hohai University, Nanjing 210098 (China); Wang, Peifang, E-mail: pfwang2005@hhu.edu.cn [Key Laboratory of Integrated Regulation and Resources Development on Shallow Lakes, Ministry of Education, Hohai University, Nanjing 210098 (China); College of Environment, Hohai University, Nanjing 210098 (China); You, Guoxiang; Miao, Lingzhan; Lv, Bowen; Yang, Yangyang [Key Laboratory of Integrated Regulation and Resources Development on Shallow Lakes, Ministry of Education, Hohai University, Nanjing 210098 (China); College of Environment, Hohai University, Nanjing 210098 (China)

2016-11-15

The effects of CeO{sub 2} nanoparticles (CeO{sub 2} NPs) on a sequencing batch biofilm reactor (SBBR) with established biological phosphorus (P) removal were investigated from the processes of anaerobic P release and aerobic P uptake. At low concentration (0.1 mg/L), no significant impact was observed on total phosphorus (TP) removal after operating for 8 h. However, at a concentration of 20 mg/L, TP removal efficiency decreased from 83.68% to 55.88% and 16.76% when the CeO{sub 2} NPs were added at the beginning of the anaerobic and aerobic periods, respectively. Further studies illustrated that the inhibition of the specific P release rate was caused by the reversible states of Ce{sup 3+} and Ce{sup 4+}, which inhibited the activity of exopolyphosphatase (PPX) and transformation of poly-β-hydoxyalkanoates (PHA) and glycogen, as well as the uptake of volatile fatty acids (VFAs). The decrease in the specific P uptake rate was mainly attributed to the significantly suppressed energy generation and decreased abundance of Burkholderia caused by excess reactive oxygen species. The removal of chemical oxygen demand (COD) was not influenced by CeO{sub 2} NPs under aerobic conditions, due to the increased abundance of Acetobacter and Acidocella after exposure. The inhibitory effects of CeO{sub 2} NPs with molecular oxygen were reduced after anaerobic exposure due to the enhanced particle size and the presence of Ce{sup 3+}. - Highlights: • CeO{sub 2} NPs (20 mg/L) had a notable toxicity effect on P removal in SBBR system. • The deteriorated SPRR was caused by the inhibited key enzyme activity (PPX). • The decreased SPUR was caused by the bacterial community shifts. • Ce ions converting and excess ROS generation are related toxicity mechanisms.

HECT E3 Ubiquitin Ligase Itch Functions as a Novel Negative Regulator of Gli-Similar 3 (Glis3 Transcriptional Activity.

Directory of Open Access Journals (Sweden)

Gary T ZeRuth

Full Text Available The transcription factor Gli-similar 3 (Glis3 plays a critical role in the generation of pancreatic ß cells and the regulation insulin gene transcription and has been implicated in the development of several pathologies, including type 1 and 2 diabetes and polycystic kidney disease. However, little is known about the proteins and posttranslational modifications that regulate or mediate Glis3 transcriptional activity. In this study, we identify by mass-spectrometry and yeast 2-hybrid analyses several proteins that interact with the N-terminal region of Glis3. These include the WW-domain-containing HECT E3 ubiquitin ligases, Itch, Smurf2, and Nedd4. The interaction between Glis3 and the HECT E3 ubiquitin ligases was verified by co-immunoprecipitation assays and mutation analysis. All three proteins interact through their WW-domains with a PPxY motif located in the Glis3 N-terminus. However, only Itch significantly contributed to Glis3 polyubiquitination and reduced Glis3 stability by enhancing its proteasomal degradation. Itch-mediated degradation of Glis3 required the PPxY motif-dependent interaction between Glis3 and the WW-domains of Itch as well as the presence of the Glis3 zinc finger domains. Transcription analyses demonstrated that Itch dramatically inhibited Glis3-mediated transactivation and endogenous Ins2 expression by increasing Glis3 protein turnover. Taken together, our study identifies Itch as a critical negative regulator of Glis3-mediated transcriptional activity. This regulation provides a novel mechanism to modulate Glis3-driven gene expression and suggests that it may play a role in a number of physiological processes controlled by Glis3, such as insulin transcription, as well as in Glis3-associated diseases.

Rescue of HIV-1 release by targeting widely divergent NEDD4-type ubiquitin ligases and isolated catalytic HECT domains to Gag.

Directory of Open Access Journals (Sweden)

Eric R Weiss

2010-09-01

Full Text Available Retroviruses engage the ESCRT pathway through late assembly (L domains in Gag to promote virus release. HIV-1 uses a PTAP motif as its primary L domain, which interacts with the ESCRT-I component Tsg101. In contrast, certain other retroviruses primarily use PPxY-type L domains, which constitute ligands for NEDD4-type ubiquitin ligases. Surprisingly, although HIV-1 Gag lacks PPxY motifs, the release of HIV-1 L domain mutants is potently enhanced by ectopic NEDD4-2s, a native isoform with a naturally truncated C2 domain that appears to account for the residual titer of L domain-defective HIV-1. The reason for the unique potency of the NEDD4-2s isoform has remained unclear. We now show that the naturally truncated C2 domain of NEDD4-2s functions as an autonomous Gag-targeting module that can be functionally replaced by the unrelated Gag-binding protein cyclophilin A (CypA. The residual C2 domain of NEDD4-2s was sufficient to transfer the ability to stimulate HIV-1 budding to other NEDD4 family members, including the yeast homologue Rsp5, and even to isolated catalytic HECT domains. The isolated catalytic domain of NEDD4-2s also efficiently promoted HIV-1 budding when targeted to Gag via CypA. We conclude that the regions typically required for substrate recognition by HECT ubiquitin ligases are all dispensable to stimulate HIV-1 release, implying that the relevant target for ubiquitination is Gag itself or can be recognized by divergent isolated HECT domains. However, the mere ability to ubiquitinate Gag was not sufficient to stimulate HIV-1 budding. Rather, our results indicate that the synthesis of K63-linked ubiquitin chains is critical for ubiquitin ligase-mediated virus release.

Influence of CeO2 NPs on biological phosphorus removal and bacterial community shifts in a sequencing batch biofilm reactor with the differential effects of molecular oxygen

International Nuclear Information System (INIS)

Xu, Yi; Wang, Chao; Hou, Jun; Wang, Peifang; You, Guoxiang; Miao, Lingzhan; Lv, Bowen; Yang, Yangyang

2016-01-01

The effects of CeO 2 nanoparticles (CeO 2 NPs) on a sequencing batch biofilm reactor (SBBR) with established biological phosphorus (P) removal were investigated from the processes of anaerobic P release and aerobic P uptake. At low concentration (0.1 mg/L), no significant impact was observed on total phosphorus (TP) removal after operating for 8 h. However, at a concentration of 20 mg/L, TP removal efficiency decreased from 83.68% to 55.88% and 16.76% when the CeO 2 NPs were added at the beginning of the anaerobic and aerobic periods, respectively. Further studies illustrated that the inhibition of the specific P release rate was caused by the reversible states of Ce 3+ and Ce 4+ , which inhibited the activity of exopolyphosphatase (PPX) and transformation of poly-β-hydoxyalkanoates (PHA) and glycogen, as well as the uptake of volatile fatty acids (VFAs). The decrease in the specific P uptake rate was mainly attributed to the significantly suppressed energy generation and decreased abundance of Burkholderia caused by excess reactive oxygen species. The removal of chemical oxygen demand (COD) was not influenced by CeO 2 NPs under aerobic conditions, due to the increased abundance of Acetobacter and Acidocella after exposure. The inhibitory effects of CeO 2 NPs with molecular oxygen were reduced after anaerobic exposure due to the enhanced particle size and the presence of Ce 3+ . - Highlights: • CeO 2 NPs (20 mg/L) had a notable toxicity effect on P removal in SBBR system. • The deteriorated SPRR was caused by the inhibited key enzyme activity (PPX). • The decreased SPUR was caused by the bacterial community shifts. • Ce ions converting and excess ROS generation are related toxicity mechanisms.

75 FR 16201 - FPL Energy Point Beach, LLC; Point Beach Nuclear Plant, Units 1 and 2; Exemption

Science.gov (United States)

2010-03-31

... NUCLEAR REGULATORY COMMISSION [Docket Nos. 50-266 and 50-301; NRC-2010-0123] FPL Energy Point Beach, LLC; Point Beach Nuclear Plant, Units 1 and 2; Exemption 1.0 Background FPL Energy Point Beach.... Borchardt (NRC) to M. S. Fertel (Nuclear Energy Institute) dated June 4, 2009. The licensee's request for an...

Organic particulate matter formation at varying relative humidity using surrogate secondary and primary organic compounds with activity corrections in the condensed phase obtained using a method based on the Wilson equation

Directory of Open Access Journals (Sweden)

E. I. Chang

2010-06-01

Full Text Available Secondary organic aerosol (SOA formation in the atmosphere is currently often modeled using a multiple lumped "two-product" (N·2p approach. The N·2p approach neglects: 1 variation of activity coefficient (ζ_i values and mean molecular weight px solid #000; color: #000;">MW in the particulate matter (PM phase; 2 water uptake into the PM; and 3 the possibility of phase separation in the PM. This study considers these effects by adopting an (N·2p^{ζ_ppx solid #000; color: #000;">MW,ζ} approach (θ is a phase index. Specific chemical structures are assigned to 25 lumped SOA compounds and to 15 representative primary organic aerosol (POA compounds to allow calculation of ζ_i and px solid #000; color: #000;">MW values. The SOA structure assignments are based on chamber-derived 2p gas/particle partition coefficient values coupled with known effects of structure on vapor pressure p_L,i^o (atm. To facilitate adoption of the (N·2p^{ζ_ppx solid #000; color: #000;">MW,θ} approach in large-scale models, this study also develops CP-Wilson.1 (Chang-Pankow-Wilson.1, a group-contribution ζ_i-prediction method that is more computationally economical than the UNIFAC model of Fredenslund et al. (1975. Group parameter values required by CP-Wilson.1 are obtained by fitting ζ_i values to predictions from UNIFAC. The (N·2p^{ζ_ppx solid #000; color: #000;">MW,θ} approach is applied (using CP-Wilson.1 to several real α-pinene/O₃ chamber cases for high reacted hydrocarbon levels (ΔHC≈400 to 1000 μg m⁻³ when relative humidity (RH ≈50%. Good agreement between the chamber and predicted results is

Dietary supplementation of chelated selenium and broiler chicken meat qualitySuplementação de selênio quelatado na ração e qualidade da carne de frango

Directory of Open Access Journals (Sweden)

Massami Shimokomaki

2012-02-01

Full Text Available The glutathione peroxidase (GSH-Px is selenium-containing enzyme, which catalyses the reduction of hydrogen peroxides and lipid hydroperoxides preventing the oxidative damages in animal tissues. The selenium (Se deficiency increases the need for vitamin E. The aim of this study was to investigate the effect of dietary supplementation of chelated Se on the poultry meat quality. Fourteen Cobb chicks with 1 day of age were divided into two groups: C-Control group (without supplementation and S-Supplemented group (with 0.03mg of chelated Se.kg-1 of feed. Birds at 42 days of age were slaughtered and boneless skinless chicken thighs were collected and stored at –18ºC for 30 days. Thighs were analyzed for the cooking loss, lipid oxidation by Thiobarbituric-Acid-Reactive Substances (TBARS and GSH-Px activity by coupled assay procedure recording the NADPH (nicotinamide adenine dinucleotide phosphate reduced oxidation. Samples of Supplemented group presented 33.8% less water after cooking (p ? 0.05 and were 23.6% (p ? 0.10 less oxidized when compared with samples of group Control. The GSH-Px activity of thighs did not differ significantly (p> 0.05 between groups Supplemented and Control. The supplementation with 0.03mg of Se in the kg of feed improved the meat quality by reducing the lipid oxidation and cooking loss, however did not increase the GSH-Px activity.O selênio (Se é componente da enzima glutationa peroxidase (GSH-Px que catalisa a redução de peróxido de hidrogênio e peróxido lipídico, prevenindo danos oxidativos nos tecidos animais. A deficiência de Se aumenta a necessidade de vitamina E pelos animais. O objetivo deste trabalho foi avaliar o efeito da suplementação de selênio quelatado sobre a qualidade da carne de frango. Os 14 pintinhos de corte da linhagem Cobb de 1 dia de idade foram divididos em 2 grupos: C-Controle (sem suplementação e S-Suplementado com 0,03mg Se quelatado. kg-1 de ração. Os frangos com 42 dias de

Teach yourself visually PowerPoint 2013

CERN Document Server

Wood, William

2013-01-01

A straightforward, visual approach to learning the new PowerPoint 2013! PowerPoint 2013 boasts updated features and new possibilities; this highly visual tutorial provides step-by-step instructions to help you learn all the capabilities of PowerPoint 2013. It covers the basics, as well as all the exciting new changes and additions in a series of easy-to-follow, full-color, two-page tutorials. Learn how to create slides, dress them up using templates and graphics, add sound and animation, and more. This book is the ideal ""show me, don't tell me"" guide to PowerPoint 2013.De

Cleaning Massive Sonar Point Clouds

DEFF Research Database (Denmark)

Arge, Lars Allan; Larsen, Kasper Green; Mølhave, Thomas

2010-01-01

We consider the problem of automatically cleaning massive sonar data point clouds, that is, the problem of automatically removing noisy points that for example appear as a result of scans of (shoals of) fish, multiple reflections, scanner self-reflections, refraction in gas bubbles, and so on. We...

Mathematical points as didactical ideas

DEFF Research Database (Denmark)

Mogensen, Arne

Mathematics teaching in Denmark was recently recommended better organized in sequences with clear mathematical pedagogical goals and a focus on mathematical points. In this paper I define a mathematical point and inform on coding of transcripts in a video based Danish research study on grade 8 te...

Endogenizing Prospect Theory's Reference Point

OpenAIRE

Ulrich Schmidt; Horst Zank

2010-01-01

In previous models of (cumulative) prospect theory reference-dependence of preferences is imposed beforehand and the location of the reference point is exogenously determined. This note provides a foundation of prospect theory, where reference-dependence is derived from preference conditions and a unique reference point arises endogenously.

Flat Coalgebraic Fixed Point Logics

Science.gov (United States)

Schröder, Lutz; Venema, Yde

Fixed point logics are widely used in computer science, in particular in artificial intelligence and concurrency. The most expressive logics of this type are the μ-calculus and its relatives. However, popular fixed point logics tend to trade expressivity for simplicity and readability, and in fact often live within the single variable fragment of the μ-calculus. The family of such flat fixed point logics includes, e.g., CTL, the *-nesting-free fragment of PDL, and the logic of common knowledge. Here, we extend this notion to the generic semantic framework of coalgebraic logic, thus covering a wide range of logics beyond the standard μ-calculus including, e.g., flat fragments of the graded μ-calculus and the alternating-time μ-calculus (such as ATL), as well as probabilistic and monotone fixed point logics. Our main results are completeness of the Kozen-Park axiomatization and a timed-out tableaux method that matches ExpTime upper bounds inherited from the coalgebraic μ-calculus but avoids using automata.

Dynamic scaling near the lambda point of liquid helium and at bicritical points

International Nuclear Information System (INIS)

Dohm, V.

1979-02-01

The critical dynamics of liquid helium and of uniaxial antiferromagnets at bicritical points are studied by means of renormalized field theory. The problem of dynamic scaling is analyzed in detail. Explicit calculations are performed using the epsilon-expansion in d = 4 - epsilon dimensions. Results in one- and two-loop order, i.e. first and second order in epsilon, are obtained for dynamic critical exponents, dynamic transient exponents, amplitude ratios and scaling functions at and above the critical points. (orig.)

The Philosophy of Turning Points

DEFF Research Database (Denmark)

Turcan, Romeo V.

2013-01-01

business and management field, the turning point is seen as a valuable unit of analysis within the research field. It is expected that this paper will encourage a dynamic scholarly conversation about the concept of turning point and how it can aid international business researchers in the development...

A fixed-point farrago

CERN Document Server

Shapiro, Joel H

2016-01-01

This text provides an introduction to some of the best-known fixed-point theorems, with an emphasis on their interactions with topics in analysis. The level of exposition increases gradually throughout the book, building from a basic requirement of undergraduate proficiency to graduate-level sophistication. Appendices provide an introduction to (or refresher on) some of the prerequisite material and exercises are integrated into the text, contributing to the volume’s ability to be used as a self-contained text. Readers will find the presentation especially useful for independent study or as a supplement to a graduate course in fixed-point theory. The material is split into four parts: the first introduces the Banach Contraction-Mapping Principle and the Brouwer Fixed-Point Theorem, along with a selection of interesting applications; the second focuses on Brouwer’s theorem and its application to John Nash’s work; the third applies Brouwer’s theorem to spaces of infinite dimension; and the fourth rests ...

Mechanistic spatio-temporal point process models for marked point processes, with a view to forest stand data

DEFF Research Database (Denmark)

Møller, Jesper; Ghorbani, Mohammad; Rubak, Ege Holger

We show how a spatial point process, where to each point there is associated a random quantitative mark, can be identified with a spatio-temporal point process specified by a conditional intensity function. For instance, the points can be tree locations, the marks can express the size of trees......, and the conditional intensity function can describe the distribution of a tree (i.e., its location and size) conditionally on the larger trees. This enable us to construct parametric statistical models which are easily interpretable and where likelihood-based inference is tractable. In particular, we consider maximum...

Active point out-of-plane ultrasound calibration

Science.gov (United States)

Cheng, Alexis; Guo, Xiaoyu; Zhang, Haichong K.; Kang, Hyunjae; Etienne-Cummings, Ralph; Boctor, Emad M.

2015-03-01

Image-guided surgery systems are often used to provide surgeons with informational support. Due to several unique advantages such as ease of use, real-time image acquisition, and no ionizing radiation, ultrasound is a common intraoperative medical imaging modality used in image-guided surgery systems. To perform advanced forms of guidance with ultrasound, such as virtual image overlays or automated robotic actuation, an ultrasound calibration process must be performed. This process recovers the rigid body transformation between a tracked marker attached to the transducer and the ultrasound image. Point-based phantoms are considered to be accurate, but their calibration framework assumes that the point is in the image plane. In this work, we present the use of an active point phantom and a calibration framework that accounts for the elevational uncertainty of the point. Given the lateral and axial position of the point in the ultrasound image, we approximate a circle in the axial-elevational plane with a radius equal to the axial position. The standard approach transforms all of the imaged points to be a single physical point. In our approach, we minimize the distances between the circular subsets of each image, with them ideally intersecting at a single point. We simulated in noiseless and noisy cases, presenting results on out-of-plane estimation errors, calibration estimation errors, and point reconstruction precision. We also performed an experiment using a robot arm as the tracker, resulting in a point reconstruction precision of 0.64mm.

A scalable and multi-purpose point cloud server (PCS) for easier and faster point cloud data management and processing

Science.gov (United States)

Cura, Rémi; Perret, Julien; Paparoditis, Nicolas

2017-05-01

In addition to more traditional geographical data such as images (rasters) and vectors, point cloud data are becoming increasingly available. Such data are appreciated for their precision and true three-Dimensional (3D) nature. However, managing point clouds can be difficult due to scaling problems and specificities of this data type. Several methods exist but are usually fairly specialised and solve only one aspect of the management problem. In this work, we propose a comprehensive and efficient point cloud management system based on a database server that works on groups of points (patches) rather than individual points. This system is specifically designed to cover the basic needs of point cloud users: fast loading, compressed storage, powerful patch and point filtering, easy data access and exporting, and integrated processing. Moreover, the proposed system fully integrates metadata (like sensor position) and can conjointly use point clouds with other geospatial data, such as images, vectors, topology and other point clouds. Point cloud (parallel) processing can be done in-base with fast prototyping capabilities. Lastly, the system is built on open source technologies; therefore it can be easily extended and customised. We test the proposed system with several billion points obtained from Lidar (aerial and terrestrial) and stereo-vision. We demonstrate loading speeds in the ˜50 million pts/h per process range, transparent-for-user and greater than 2 to 4:1 compression ratio, patch filtering in the 0.1 to 1 s range, and output in the 0.1 million pts/s per process range, along with classical processing methods, such as object detection.

Acid dew point measurement in flue gases

Energy Technology Data Exchange (ETDEWEB)

Struschka, M.; Baumbach, G.

1986-06-01

The operation of modern boiler plants requires the continuous measurement of the acid dew point in flue gases. An existing measuring instrument was modified in such a way that it can determine acid dew points reliably, reproduceably and continuously. The authors present the mechanisms of the dew point formation, the dew point measuring principle, the modification and the operational results.

Improved Dynamic Planar Point Location

DEFF Research Database (Denmark)

Brodal, Gerth Stølting; Arge, Lars; Georgiadis, Loukas

2006-01-01

We develop the first linear-space data structures for dynamic planar point location in general subdivisions that achieve logarithmic query time and poly-logarithmic update time.......We develop the first linear-space data structures for dynamic planar point location in general subdivisions that achieve logarithmic query time and poly-logarithmic update time....

Behavior of mercury in the formic acid vent condenser. Final report

International Nuclear Information System (INIS)

Zamecnik, J.R.

1996-01-01

The concentrations of mercury at the FAVC inlet and exit were measured during the BL1 and PX6 runs of the Integrated DWPF Melter System (IDMS) with the HEME bypassed and without the ammonia scrubber. The results showed that mercury concentrations of approximately 1.02-12.7 (mean 5.74) times saturation occurred at the FAVC exit. The concentration of mercury at the FAVC inlet was found to be 0.66-6.2 times the saturation value (based on the SRAT condenser exit). In the PX7 run, the ammonia scrubber was used and the FAVC HEME was not bypassed. The results from this run showed that the FAVC inlet concentrations again were above saturation (1.45-15.5 times saturation), but that the FAVC exit concentrations were only 0.02-0.41 times saturation (except for one data point at 1.61 times saturation). Operation of the FAVC without the HEME could therefore result in FAVC exit mercury concentrations of greater than 5.74 times saturation, which would result in DWPF emitting greater than 405 lb/yr of mercury at 100 percent attainment; this quantity is well in excess of the permit limit of 175 lb/yr (for all of DWPF). However, with the HEME in place, the emissions are predicted to be only about 40 lb/yr for an FAVC exit temperature of 10 degrees C. The experimental results also indicate that the ammonia scrubbers have little effect on the removal of mercury

Effects of dietary supplementation of Artemisia argyi aqueous extract on antioxidant indexes of small intestine in broilers.

Science.gov (United States)

Zhao, Fei; Shi, Binlin; Sun, Dengsheng; Chen, Hongyan; Tong, Manman; Zhang, Pengfei; Guo, Xiaoyu; Yan, Sumei

2016-09-01

The present study was conducted to investigate the effect of Artemisia argyi aqueous extract (AAE) on antioxidant indexes in the small intestine. A total of 192 Arbor Acre broiler chickens (one-day-old) were randomly divided into 4 treatments with 6 replicates of 8 chickens. These 4 diets were formulated by adding 0, 500, 1,000 and 2,000 mg/kg AAE to the basal diet. The results showed as follows: 1) compared with the control, the total antioxidant capacity (T-AOC) in ileum for the 2,000 mg/kg treatment group was significantly increased at 21 days of age ( P  < 0.05); the T-AOC levels in jejunum and ileum were significantly increased in broilers supplemented with 500 mg/kg AAE at 42 days of age ( P  < 0.05), and the T-AOC levels in jejunum and ileum were significantly improved in 1,000 mg/kg treatment group ( P  < 0.01). 2) At 21 days of age, supplementation of 500 mg/kg AAE significantly increased the catalase (CAT) activity of small intestine, and the glutathione peroxidase (GSH-Px) activity of jejunum was improved ( P  < 0.01), meanwhile, the GSH-Px activity of duodenum and the total superoxide dismutase (T-SOD) activity of duodenum and jejunum were significantly higher than those of the control group ( P  < 0.05); supplementation of 1,000 mg/kg AAE significantly increased the CAT activity of duodenum and ileum and the GSH-Px activity of duodenum and jejunum ( P  < 0.05), and the ileum GSH-Px activity was significantly increased ( P  < 0.01); supplementation of 2,000 mg/kg AAE significantly increased the CAT activity of duodenum and ileum ( P  < 0.05). At 42 days of age, supplementation of 500 mg/kg AAE significantly increased the GSH-Px activity of ileum and the T-SOD activity of duodenum ( P  < 0.05), meanwhile, the T-SOD activity of jejunum was significantly increased ( P  < 0.01); supplementation of 1,000 mg/kg AAE significantly increased the CAT activity of jejunum and the T-SOD activity of ileum ( P  < 0.01), and the GSH-Px

Dose point kernels for beta-emitting radioisotopes

International Nuclear Information System (INIS)

Prestwich, W.V.; Chan, L.B.; Kwok, C.S.; Wilson, B.

1986-01-01

Knowledge of the dose point kernel corresponding to a specific radionuclide is required to calculate the spatial dose distribution produced in a homogeneous medium by a distributed source. Dose point kernels for commonly used radionuclides have been calculated previously using as a basis monoenergetic dose point kernels derived by numerical integration of a model transport equation. The treatment neglects fluctuations in energy deposition, an effect which has been later incorporated in dose point kernels calculated using Monte Carlo methods. This work describes new calculations of dose point kernels using the Monte Carlo results as a basis. An analytic representation of the monoenergetic dose point kernels has been developed. This provides a convenient method both for calculating the dose point kernel associated with a given beta spectrum and for incorporating the effect of internal conversion. An algebraic expression for allowed beta spectra has been accomplished through an extension of the Bethe-Bacher approximation, and tested against the exact expression. Simplified expression for first-forbidden shape factors have also been developed. A comparison of the calculated dose point kernel for 32 P with experimental data indicates good agreement with a significant improvement over the earlier results in this respect. An analytic representation of the dose point kernel associated with the spectrum of a single beta group has been formulated. 9 references, 16 figures, 3 tables

Infra-red fixed points in supersymmetry

Indian Academy of Sciences (India)

¾c /font>, and c stands for the color quadratic Casimir of the field. Fixed points arise when R* ¼ or when R*. /nobr>. ´S-½. µ ´r ·b¿µ. The stability of the solutions may be tested by linearizing the system about the fixed points. For the non-trivial fixed points we need to consider the eigenvalues of the stability matrix whose ...

Fixed-point signal processing

CERN Document Server

Padgett, Wayne T

2009-01-01

This book is intended to fill the gap between the ""ideal precision"" digital signal processing (DSP) that is widely taught, and the limited precision implementation skills that are commonly required in fixed-point processors and field programmable gate arrays (FPGAs). These skills are often neglected at the university level, particularly for undergraduates. We have attempted to create a resource both for a DSP elective course and for the practicing engineer with a need to understand fixed-point implementation. Although we assume a background in DSP, Chapter 2 contains a review of basic theory

The succinonitrile triple-point standard: a fixed point to improve the accuracy of temperature measurements in the clinical laboratory.

Science.gov (United States)

Mangum, B W

1983-07-01

In an investigation of the melting and freezing behavior of succinonitrile, the triple-point temperature was determined to be 58.0805 degrees C, with an estimated uncertainty of +/- 0.0015 degrees C relative to the International Practical Temperature Scale of 1968 (IPTS-68). The triple-point temperature of this material is evaluated as a temperature-fixed point, and some clinical laboratory applications of this fixed point are proposed. In conjunction with the gallium and ice points, the availability of succinonitrile permits thermistor thermometers to be calibrated accurately and easily on the IPTS-68.

Model plant Key Measurement Points

International Nuclear Information System (INIS)

Schneider, R.A.

1984-01-01

For IAEA safeguards a Key Measurement Point is defined as the location where nuclear material appears in such a form that it may be measured to determine material flow or inventory. This presentation describes in an introductory manner the key measurement points and associated measurements for the model plant used in this training course

Heilbronn problem for five points

International Nuclear Information System (INIS)

Yang Lu; Zhang Jingzhong; Zeng Zhenbing

1991-08-01

Put 5 points in a unit square, then there must be at least one triangle, formed by three of these points, with an area not greater than √3/9. And the upper bound √3/9 is the best. Unexpectedly, this disproves an old conjecture posed twenty years ago. (author). 15 refs, 19 figs

Marine Point Forecasts

Science.gov (United States)

will link to the zone forecast and then allow further zooming to the point of interest whereas on the Honolulu, HI Chicago, IL Northern Indiana, IN Lake Charles, LA New Orleans, LA Boston, MA Caribou, ME

Smooth random change point models.

Science.gov (United States)

van den Hout, Ardo; Muniz-Terrera, Graciela; Matthews, Fiona E

2011-03-15

Change point models are used to describe processes over time that show a change in direction. An example of such a process is cognitive ability, where a decline a few years before death is sometimes observed. A broken-stick model consists of two linear parts and a breakpoint where the two lines intersect. Alternatively, models can be formulated that imply a smooth change between the two linear parts. Change point models can be extended by adding random effects to account for variability between subjects. A new smooth change point model is introduced and examples are presented that show how change point models can be estimated using functions in R for mixed-effects models. The Bayesian inference using WinBUGS is also discussed. The methods are illustrated using data from a population-based longitudinal study of ageing, the Cambridge City over 75 Cohort Study. The aim is to identify how many years before death individuals experience a change in the rate of decline of their cognitive ability. Copyright © 2010 John Wiley & Sons, Ltd.

ACS Photometric Zero Point Verification

Science.gov (United States)

Dolphin, Andrew

2003-07-01

The uncertainties in the photometric zero points create a fundamental limit to the accuracy of photometry. The current state of the ACS calibration is surprisingly poor, with zero point uncertainties of 0.03 magnitudes in the Johnson filters. The reason for this is that ACS observations of excellent ground-based standard fields, such as the omega Cen field used for WFPC2 calibrations, have not been obtained. Instead, the ACS photometric calibrations are based primarily on semi-emprical synthetic zero points and observations of fields too crowded for accurate ground-based photometry. I propose to remedy this problem by obtaining ACS broadband images of the omega Cen standard field with both the WFC and HRC. This will permit the direct determination of the ACS transformations, and is expected to double the accuracy to which the ACS zero points are known. A second benefit is that it will facilitate the comparison of the WFPC2 and ACS photometric systems, which will be important as WFPC2 is phased out and ACS becomes HST's primary imager.

Zero point energy of renormalized Wilson loops

International Nuclear Information System (INIS)

Hidaka, Yoshimasa; Pisarski, Robert D.

2009-01-01

The quark-antiquark potential, and its associated zero point energy, can be extracted from lattice measurements of the Wilson loop. We discuss a unique prescription to renormalize the Wilson loop, for which the perturbative contribution to the zero point energy vanishes identically. A zero point energy can arise nonperturbatively, which we illustrate by considering effective string models. The nonperturbative contribution to the zero point energy vanishes in the Nambu model, but is nonzero when terms for extrinsic curvature are included. At one loop order, the nonperturbative contribution to the zero point energy is negative, regardless of the sign of the extrinsic curvature term.

Microsoft SharePoint 2013 disaster recovery guide

CERN Document Server

Ward, Peter

2013-01-01

The style and approach of the book is an easytoread SharePoint admin guide. This is not a stepbystep instruction book, but rather a guide on how to implement and execute a disaster recovery plan to your SharePoint environment.This book is great for both SharePoint and SQL administrators new to the SharePoint 2013 architecture, and who are looking to get a good grounding in how to use implement a solid disaster recoveryrecovery plan. It's assumed that you have some experience in SharePoint and Windows Server and, as well be familiar with SQL.

Point-to-point radio link variation at E-band and its effect on antenna design

NARCIS (Netherlands)

Al-Rawi, A.; Dubok, A.; Herben, M.H.A.J.; Smolders, A.B.

2015-01-01

Radio propagation will strongly influence the design of the antenna and front-end components of E-band point-to-point communication systems. Based on the ITU rain model, the rain attenuation is estimated in a statistical sense and it is concluded that for backhaul links of 1–10 km, antennas with a

Bayesian analysis of Markov point processes

DEFF Research Database (Denmark)

Berthelsen, Kasper Klitgaard; Møller, Jesper

2006-01-01

Recently Møller, Pettitt, Berthelsen and Reeves introduced a new MCMC methodology for drawing samples from a posterior distribution when the likelihood function is only specified up to a normalising constant. We illustrate the method in the setting of Bayesian inference for Markov point processes...... a partially ordered Markov point process as the auxiliary variable. As the method requires simulation from the "unknown" likelihood, perfect simulation algorithms for spatial point processes become useful....

Some results about the global attractivity of bounded solutions of difference equations with applications to periodic solutions

International Nuclear Information System (INIS)

Dehghan, Mehdi; Mazrooei-Sebdani, Reza

2007-01-01

We obtain some results about the global attractivity of bounded solutions of difference equation x n+1 =f(x n ,x n-1 ,...,x n-k ), n=0,1,... where f is non-increasing or non-decreasing in each argument and every point in I is an equilibrium point of above equation where I is an invariant interval for this equation. By our results we prove that when k is an odd positive integer and p>=1 is a real number, every positive solution ofx n+1 =p+x n-k 1+x n ,n=0,1,...converges to a period-two solution of this equation. We also apply our results to the rational difference equationx n+1 =1+x n-2k+1 x n-2l ,n=0,1,...where k,l-bar {0,1,...}, and we show that every positive solution of this equation converges to a period-two solution of this equation

Cystoviral polymerase complex protein P7 uses its acidic C-terminal tail to regulate the RNA-directed RNA polymerase P2.

Science.gov (United States)

Alphonse, Sébastien; Arnold, Jamie J; Bhattacharya, Shibani; Wang, Hsin; Kloss, Brian; Cameron, Craig E; Ghose, Ranajeet

2014-07-15

In bacteriophages of the cystovirus family, the polymerase complex (PX) encodes a 75-kDa RNA-directed RNA polymerase (P2) that transcribes the double-stranded RNA genome. Also a constituent of the PX is the essential protein P7 that, in addition to accelerating PX assembly and facilitating genome packaging, plays a regulatory role in transcription. Deletion of P7 from the PX leads to aberrant plus-strand synthesis suggesting its influence on the transcriptase activity of P2. Here, using solution NMR techniques and the P2 and P7 proteins from cystovirus ϕ12, we demonstrate their largely electrostatic interaction in vitro. Chemical shift perturbations on P7 in the presence of P2 suggest that this interaction involves the dynamic C-terminal tail of P7, more specifically an acidic cluster therein. Patterns of chemical shift changes induced on P2 by the P7 C-terminus resemble those seen in the presence of single-stranded RNA suggesting similarities in binding. This association between P2 and P7 reduces the affinity of the former toward template RNA and results in its decreased activity both in de novo RNA synthesis and in extending a short primer. Given the presence of C-terminal acidic tracts on all cystoviral P7 proteins, the electrostatic nature of the P2/P7 interaction is likely conserved within the family and could constitute a mechanism through which P7 regulates transcription in cystoviruses. Copyright © 2014 Elsevier Ltd. All rights reserved.

Multi-point probe for testing electrical properties and a method of producing a multi-point probe

DEFF Research Database (Denmark)

2011-01-01

A multi-point probe for testing electrical properties of a number of specific locations of a test sample comprises a supporting body defining a first surface, a first multitude of conductive probe arms (101-101'''), each of the probe arms defining a proximal end and a distal end. The probe arms...... of contact with the supporting body, and a maximum thickness perpendicular to its perpendicular bisector and its line of contact with the supporting body. Each of the probe arms has a specific area or point of contact (111-111''') at its distal end for contacting a specific location among the number...... of specific locations of the test sample. At least one of the probe arms has an extension defining a pointing distal end providing its specific area or point of contact located offset relative to its perpendicular bisector....

An X-point ergodic divertor

International Nuclear Information System (INIS)

Chu, M.S.; Jensen, T.H.; La Haye, R.J.; Taylor, T.S.; Evans, T.E.

1991-10-01

A new ergodic divertor is proposed. It utilizes a system of external (n = 3) coils arranged to generate overlapping magnetic islands in the edge region of a diverted tokamak and connect the randomized field lines to the external (cold) divertor plate. The novel feature in the configuration is the placement of the external coils close to the X-point. A realistic design of the external coil set is studied by using the field line tracing method for a low aspect ratio (A ≅ 3) tokamak. Two types of effects are observed. First, by placing the coils close to the X-point, where the poloidal magnetic field is weak and the rational surfaces are closely packed only a moderate amount of current in the external coils is needed to ergodize the edge region. This ergodized edge enhances the edge transport in the X-point region and leads to the potential of edge profile control and the avoidance of edge localized modes (ELMs). Furthermore, the trajectories of the field lines close to the X-point are modified by the external coil set, causing the hit points on the external divertor plates to be randomized and spread out in the major radius direction. A time-dependent modulation of the currents in the external (n = 3) coils can potentially spread the heat flux more uniformly on the divertor plate avoiding high concentration of the heat flux. 10 refs., 9 figs

Near-point string: Simple method to demonstrate anticipated near point for multifocal and accommodating intraocular lenses.

Science.gov (United States)

George, Monica C; Lazer, Zane P; George, David S

2016-05-01

We present a technique that uses a near-point string to demonstrate the anticipated near point of multifocal and accommodating intraocular lenses (IOLs). Beads are placed on the string at distances corresponding to the near points for diffractive and accommodating IOLs. The string is held up to the patient's eye to demonstrate where each of the IOLs is likely to provide the best near vision. None of the authors has a financial or proprietary interest in any material or method mentioned. Copyright © 2016 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

A new compact fixed-point blackbody furnace

International Nuclear Information System (INIS)

Hiraka, K.; Oikawa, H.; Shimizu, T.; Kadoya, S.; Kobayashi, T.; Yamada, Y.; Ishii, J.

2013-01-01

More and more NMIs are realizing their primary scale themselves with fixed-point blackbodies as their reference standard. However, commercially available fixed-point blackbody furnaces of sufficient quality are not always easy to obtain. CHINO Corp. and NMIJ, AIST jointly developed a new compact fixed-point blackbody furnace. The new furnace has such features as 1) improved temperature uniformity when compared to previous products, enabling better plateau quality, 2) adoption of the hybrid fixed-point cell structure with internal insulation to improve robustness and thereby to extend lifetime, 3) easily ejectable and replaceable heater unit and fixed-point cell design, leading to reduced maintenance cost, 4) interchangeability among multiple fixed points from In to Cu points. The replaceable cell feature facilitates long term maintenance of the scale through management of a group of fixed-point cells of the same type. The compact furnace is easily transportable and therefore can also function as a traveling standard for disseminating the radiation temperature scale, and for maintaining the scale at the secondary level and industrial calibration laboratories. It is expected that the furnace will play a key role of the traveling standard in the anticipated APMP supplementary comparison of the radiation thermometry scale

NIM Realization of the Gallium Triple Point

Science.gov (United States)

Xiaoke, Yan; Ping, Qiu; Yuning, Duan; Yongmei, Qu

2003-09-01

In the last three years (1999 to 2001), the gallium triple-point cell has been successfully developed, and much corresponding research has been carried out at the National Institute of Metrology (NIM), Beijing, China. This paper presents the cell design, apparatus and procedure for realizing the gallium triple point, and presents studies on the different freezing methods. The reproducibility is 0.03 mK, and the expanded uncertainty of realization of the gallium triple point is evaluated to be 0.17 mK (p=0.99, k=2.9). Also, the reproducibility of the gallium triple point was compared with that of the triple point of water.

Realization of Copper Melting Point for Thermocouple Calibrations

Directory of Open Access Journals (Sweden)

Y. A. ABDELAZIZ

2011-08-01

Full Text Available Although the temperature stability and uncertainty of the freezing plateau is better than that of the melting plateau in most of the thermometry fixed points, but realization of melting plateaus are easier than that of freezing plateaus for metal fixed points. It will be convenient if the melting points can be used instead of the freezing points in calibration of standard noble metal thermocouples because of easier realization and longer plateau duration of melting plateaus. In this work a comparison between the melting and freezing points of copper (Cu was carried out using standard noble metal thermocouples. Platinum - platinum 10 % rhodium (type S, platinum – 30 % rhodium / platinum 6 % rhodium (type B and platinum - palladium (Pt/Pd thermocouples are used in this study. Uncertainty budget analysis of the melting points and freezing points is presented. The experimental results show that it is possible to replace the freezing point with the melting point of copper cell in the calibration of standard noble metal thermocouples in secondary-level laboratories if the optimal methods of realization of melting points are used.

Zero Point Energy of Renormalized Wilson Loops

OpenAIRE

Hidaka, Yoshimasa; Pisarski, Robert D.

2009-01-01

The quark antiquark potential, and its associated zero point energy, can be extracted from lattice measurements of the Wilson loop. We discuss a unique prescription to renormalize the Wilson loop, for which the perturbative contribution to the zero point energy vanishes identically. A zero point energy can arise nonperturbatively, which we illustrate by considering effective string models. The nonperturbative contribution to the zero point energy vanishes in the Nambu model, but is nonzero wh...

3D reconstruction of laser projective point with projection invariant generated from five points on 2D target.

Science.gov (United States)

Xu, Guan; Yuan, Jing; Li, Xiaotao; Su, Jian

2017-08-01

Vision measurement on the basis of structured light plays a significant role in the optical inspection research. The 2D target fixed with a line laser projector is designed to realize the transformations among the world coordinate system, the camera coordinate system and the image coordinate system. The laser projective point and five non-collinear points that are randomly selected from the target are adopted to construct a projection invariant. The closed form solutions of the 3D laser points are solved by the homogeneous linear equations generated from the projection invariants. The optimization function is created by the parameterized re-projection errors of the laser points and the target points in the image coordinate system. Furthermore, the nonlinear optimization solutions of the world coordinates of the projection points, the camera parameters and the lens distortion coefficients are contributed by minimizing the optimization function. The accuracy of the 3D reconstruction is evaluated by comparing the displacements of the reconstructed laser points with the actual displacements. The effects of the image quantity, the lens distortion and the noises are investigated in the experiments, which demonstrate that the reconstruction approach is effective to contribute the accurate test in the measurement system.

Neutral-point current modeling and control for Neutral-Point Clamped three-level converter drive with small DC-link capacitors

DEFF Research Database (Denmark)

Maheshwari, Ram Krishan; Munk-Nielsen, Stig; Busquets-Monge, Sergio

2011-01-01

A Neutral-Point-Clamped (NPC) three-level inverter with small DC-link capacitors is presented in this paper. This inverter requires zero average neutral-point current for stable neutral-point potential. A simple carrier based modulation strategy is proposed for achieving zero average neutral...... drive with only 14 μF DC-link capacitors. A fast and stable performance of the neutral-point voltage controller is achieved and verified by experiments....

Some remarks on farthest points

Czech Academy of Sciences Publication Activity Database

Montesinos, V.; Zizler, P.; Zizler, Václav

2011-01-01

Roč. 105, č. 1 (2011), s. 119-131 ISSN 1578-7303 R&D Projects: GA AV ČR IAA100190901 Institutional research plan: CEZ:AV0Z10190503 Keywords : farthest points * strongly exposed points * generic differentiability * convex functions Subject RIV: BA - General Mathematics Impact factor: 0.340, year: 2011 http://link.springer.com/article/10.1007%2Fs13398-011-0012-z

Exact 2-point function in Hermitian matrix model

International Nuclear Information System (INIS)

Morozov, A.; Shakirov, Sh.

2009-01-01

J. Harer and D. Zagier have found a strikingly simple generating function [1,2] for exact (all-genera) 1-point correlators in the Gaussian Hermitian matrix model. In this paper we generalize their result to 2-point correlators, using Toda integrability of the model. Remarkably, this exact 2-point correlation function turns out to be an elementary function - arctangent. Relation to the standard 2-point resolvents is pointed out. Some attempts of generalization to 3-point and higher functions are described.

Fixed points of quantum operations

International Nuclear Information System (INIS)

Arias, A.; Gheondea, A.; Gudder, S.

2002-01-01

Quantum operations frequently occur in quantum measurement theory, quantum probability, quantum computation, and quantum information theory. If an operator A is invariant under a quantum operation φ, we call A a φ-fixed point. Physically, the φ-fixed points are the operators that are not disturbed by the action of φ. Our main purpose is to answer the following question. If A is a φ-fixed point, is A compatible with the operation elements of φ? We shall show in general that the answer is no and we shall give some sufficient conditions under which the answer is yes. Our results will follow from some general theorems concerning completely positive maps and injectivity of operator systems and von Neumann algebras

Automatic dew-point temperature sensor.

Science.gov (United States)

Graichen, H; Rascati, R; Gonzalez, R R

1982-06-01

A device is described for measuring dew-point temperature and water vapor pressure in small confined areas. The method is based on the deposition of water on a cooled surface when at dew-point temperature. A small Peltier module lowers the temperature of two electrically conductive plates. At dew point the insulating gap separating the plates becomes conductive as water vapor condenses. Sensors based on this principle can be made small and rugged and can be used for measuring directly the local water vapor pressure. They may be installed within a conventional ventilated sweat capsule used for measuring water vapor loss from the skin surface. A novel application is the measurement of the water vapor pressure gradients across layers of clothing worn by an exercising subject.

Metal Wire-array Load for Z-pinch Used as X-ray Source

Institute of Scientific and Technical Information of China (English)

1999-01-01

<正> The inertial confinement fusion （ICF） has evident minatory applications becasuse ICF ignites the fusion fuel with high energy media. As a method of ICF, Z-pinch has obtained evidently increased X-ray power PX-ray and energy EX-ray. The scientists have noticed this promising achievement. The Z-accelerator which is an operating Z-pinch device in Sandia national laboratory （SNL） in USA achieved 290 TW Px-ray in 1997 and the energy and defense departments of USA will finance SNL for a larger Z-pinch device. The early Z-pinch aimed to obtain high tempera

Maximum entropy PDF projection: A review

Science.gov (United States)

Baggenstoss, Paul M.

2017-06-01

We review maximum entropy (MaxEnt) PDF projection, a method with wide potential applications in statistical inference. The method constructs a sampling distribution for a high-dimensional vector x based on knowing the sampling distribution p(z) of a lower-dimensional feature z = T (x). Under mild conditions, the distribution p(x) having highest possible entropy among all distributions consistent with p(z) may be readily found. Furthermore, the MaxEnt p(x) may be sampled, making the approach useful in Monte Carlo methods. We review the theorem and present a case study in model order selection and classification for handwritten character recognition.

Interval Mathematics Applied to Critical Point Transitions

Directory of Open Access Journals (Sweden)

Benito A. Stradi

2012-03-01

Full Text Available The determination of critical points of mixtures is important for both practical and theoretical reasons in the modeling of phase behavior, especially at high pressure. The equations that describe the behavior of complex mixtures near critical points are highly nonlinear and with multiplicity of solutions to the critical point equations. Interval arithmetic can be used to reliably locate all the critical points of a given mixture. The method also verifies the nonexistence of a critical point if a mixture of a given composition does not have one. This study uses an interval Newton/Generalized Bisection algorithm that provides a mathematical and computational guarantee that all mixture critical points are located. The technique is illustrated using several example problems. These problems involve cubic equation of state models; however, the technique is general purpose and can be applied in connection with other nonlinear problems.

Post-Processing in the Material-Point Method

DEFF Research Database (Denmark)

Andersen, Søren; Andersen, Lars Vabbersgaard

The material-point method (MPM) is a numerical method for dynamic or static analysis of solids using a discretization in time and space. The method has shown to be successful in modelling physical problems involving large deformations, which are difficult to model with traditional numerical tools...... such as the finite element method. In the material-point method, a set of material points is utilized to track the problem in time and space, while a computational background grid is utilized to obtain spatial derivatives relevant to the physical problem. Currently, the research within the material-point method......-point method. The first idea involves associating a volume with each material point and displaying the deformation of this volume. In the discretization process, the physical domain is divided into a number of smaller volumes each represented by a simple shape; here quadrilaterals are chosen for the presented...

The Bayesian Approach to Association

Science.gov (United States)

Arora, N. S.

2017-12-01

The Bayesian approach to Association focuses mainly on quantifying the physics of the domain. In the case of seismic association for instance let X be the set of all significant events (above some threshold) and their attributes, such as location, time, and magnitude, Y1 be the set of detections that are caused by significant events and their attributes such as seismic phase, arrival time, amplitude etc., Y2 be the set of detections that are not caused by significant events, and finally Y be the set of observed detections We would now define the joint distribution P(X, Y1, Y2, Y) = P(X) P(Y1 | X) P(Y2) I(Y = Y1 + Y2) ; where the last term simply states that Y1 and Y2 are a partitioning of Y. Given the above joint distribution the inference problem is simply to find the X, Y1, and Y2 that maximizes posterior probability P(X, Y1, Y2| Y) which reduces to maximizing P(X) P(Y1 | X) P(Y2) I(Y = Y1 + Y2). In this expression P(X) captures our prior belief about event locations. P(Y1 | X) captures notions of travel time, residual error distributions as well as detection and mis-detection probabilities. While P(Y2) captures the false detection rate of our seismic network. The elegance of this approach is that all of the assumptions are stated clearly in the model for P(X), P(Y1|X) and P(Y2). The implementation of the inference is merely a by-product of this model. In contrast some of the other methods such as GA hide a number of assumptions in the implementation details of the inference - such as the so called "driver cells." The other important aspect of this approach is that all seismic knowledge including knowledge from other domains such as infrasound and hydroacoustic can be included in the same model. So, we don't need to separately account for misdetections or merge seismic and infrasound events as a separate step. Finally, it should be noted that the objective of automatic association is to simplify the job of humans who are publishing seismic bulletins based on this

Compound nucleus decay: Comparison between saddle point and scission point barriers

Energy Technology Data Exchange (ETDEWEB)

Santos, T. J.; Carlson, B. V. [Depto. de Física, Instituto Tecnológico de Aeronáutica, São José dos Campos, SP (Brazil)

2014-11-11

One of the principal characteristics of nuclear multifragmentation is the emission of complex fragments of intermediate mass. An extension of the statistical multifragmentation model has been developed, in which the process can be interpreted as the near simultaneous limit of a series of sequential binary decays. In this extension, intermediate mass fragment emissions are described by expressions almost identical to those of light particle emission. At lower temperatures, similar expressions have been shown to furnish a good description of very light intermediate mass fragment emission but not of the emission of heavier fragments, which seems to be determined by the transition density at the saddle-point rather than at the scission point. Here, we wish to compare these different formulations of intermediate fragmment emission and analyze the extent to which they remain distinguishable at high excitation energy.