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Sample records for plato iv terminal

  1. PLATO IV Accountancy Index.

    Science.gov (United States)

    Pondy, Dorothy, Comp.

    The catalog was compiled to assist instructors in planning community college and university curricula using the 48 computer-assisted accountancy lessons available on PLATO IV (Programmed Logic for Automatic Teaching Operation) for first semester accounting courses. It contains information on lesson access, lists of acceptable abbreviations for…

  2. Evaluation of a Three Year Health Sciences PLATO IV Computer-Based Education Project.

    Science.gov (United States)

    Sorlie, William E.; Essex, Diane L.

    Significant findings of the comprehensive evaluation of a computer-based curriculum in the basic medical sciences using the PLATO IV computer system are presented. The study was conducted by the Office of Curriculum and Evaluation (OCE) of the School of Basic Medical Sciences (SBMS) at the University of Illinois, Urbana/Champaign (UC). It was…

  3. A Plan for the Evaluation of a Project to Develop Basic Medical Sciences Lessons on PLATO IV.

    Science.gov (United States)

    Jones, Les A.; And Others

    A project to introduce PLATO IV computer-assisted instruction (CAI) in medical sciences education for health professionals was implemented at the School of Basic Medical Sciences at the University of Illinois. This paper describes the plan for evaluation of the project. Using a student questionnaire and additional general questions, the…

  4. The CGE-PLATO Electronic Laboratory Station Structure and Operation.

    Science.gov (United States)

    Neal, J. P.

    An electronic laboratory station was designed for student use in learning electronic instrumentation and measurement by means of the computer-guided experimentation (CGE) system. The station features rack-mounted electronic laboratory equipment on a laboratory table adjacent to a PLATO IV terminal. An integrated logic system behind the laboratory…

  5. Plato's Embryology.

    Science.gov (United States)

    Wilberding, James

    2015-01-01

    Embryology was a subject that inspired great cross-disciplinary discussion in antiquity, and Plato's Timaeus made an important contribution to this discussion, though Plato's precise views have remained a matter of controversy, especially regarding three key questions pertaining to the generation and nature of the seed: whether there is a female seed; what the nature of seed is; and whether the seed contains a preformed human being. In this paper I argue that Plato's positions on these three issues can be adequately determined, even if some other aspects of his theory cannot. In particular, it is argued that (i) Plato subscribes to the encephalo-myelogenic theory of seed, though he places particular emphasis on the soul being the true seed; (ii) Plato is a two-seed theorist, yet the female seed appears to make no contribution to reproduction; and (iii) Plato cannot be an advocate of preformationism.

  6. Terminal ileum gangrene secondary to a type IV paraesophageal hernia.

    Science.gov (United States)

    Hsu, Ching Tsai; Hsiao, Po Jen; Chiu, Chih Chien; Chan, Jenq Shyong; Lin, Yee Fung; Lo, Yuan Hung; Hsiao, Chia Jen

    2016-02-28

    Type IV paraesophageal hernia (PEH) is very rare, and is characterized by the intrathoracic herniation of the abdominal viscera other than the stomach into the chest. We describe a 78-year-old woman who presented at our emergency department because of epigastric pain that she had experienced over the past 24 h. On the day after admission, her pain became severe and was accompanied by right chest pain and dyspnea. Chest radiography revealed an intrathoracic intestinal gas bubble occupying the right lower lung field. Emergency explorative laparotomy identified a type IV PEH with herniation of only the terminal ileum through a hiatal defect into the right thoracic cavity. In this report, we also present a review of similar cases in the literature published between 1980 and 2015 in PubMed. There were four published cases of small bowel herniation into the thoracic cavity during this period. Our patient represents a rare case of an individual diagnosed with type IV PEH with incarceration of only the terminal ileum.

  7. Filsafat Ketuhanan Menurut Plato

    Directory of Open Access Journals (Sweden)

    Ivan Th.J Weismann

    2005-06-01

    Full Text Available Plato adalah filsuf pertama yang menulis secara filosofis dan secara sistematik teologis mengenai konsep Ketuhanan sehingga dapatlah dikatakan bahwa ia adalah peletqk dasar bagi ilmu teologia dan memberikan pengaruh besar bagi perkembanganfilsafat Barat khususnya tentangkonsep Ketuhanan. Pemikiran Plato tentang Ketuhanan adalah upayanya untuk mereformasi konsep Ketuhanan yang terdapat pada masyarakat Yunani kuno. Tulisan ini berupaya menganalisis dan memahami Ketuhanan menurut Plato agar pembaca masa kini dapat mengerti lebih dalam lagi tentong konsep Ketuhanan yang dipahami masyarakat Yunani kuno dan khususnya menurut Plato, dan juga dapat dijadikan sebagai bahan perbandingan bagifilsafat Ketuhanan pada masa kini. Filsafat Ketuhanan menurut Plato ini penulis jelaskan dengan memperhatikandimensi metafisika, epistemologi, dan etika.

  8. [Plato psychiatrist, Foucault platonic].

    Science.gov (United States)

    Mathov, Nicolás

    2016-05-01

    This work explores the links between the concepts of "soul", "law" and "word" in Plato's work, in order to highlight the importance and the centrality of the philosophical-therapeutic dimension in the Greek philosopher's thought. In that way, this work pretends to show that "contemporary" problems usually discussed within "Human Sciences" in general, and Psychiatry in particular, should confront their knowledge with Plato's work, mainly due to the profound influence his ideas have had in our Greco-Christian culture. In that sense, and with that objective, this work also explores Michel Foucault's lucid and controversial interpretation of Plato.

  9. C-terminal region of DNA ligase IV drives XRCC4/DNA ligase IV complex to chromatin

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Sicheng; Liu, Xunyue; Kamdar, Radhika Pankaj; Wanotayan, Rujira; Sharma, Mukesh Kumar [Research Laboratory for Nuclear Reactors and Department of Nuclear Engineering, Graduate School of Science and Engineering, Tokyo Institute of Technology, Tokyo 152-8550 (Japan); Adachi, Noritaka [Graduate School of Nanobioscience, Yokohama City University, Yokohama 236-0027 (Japan); Matsumoto, Yoshihisa, E-mail: yoshim@nr.titech.ac.jp [Research Laboratory for Nuclear Reactors and Department of Nuclear Engineering, Graduate School of Science and Engineering, Tokyo Institute of Technology, Tokyo 152-8550 (Japan)

    2013-09-20

    Highlights: •Chromatin binding of XRCC4 is dependent on the presence of DNA ligase IV. •C-terminal region of DNA ligase IV alone can recruit itself and XRCC4 to chromatin. •Two BRCT domains of DNA ligase IV are essential for the chromatin binding of XRCC4. -- Abstract: DNA ligase IV (LIG4) and XRCC4 form a complex to ligate two DNA ends at the final step of DNA double-strand break (DSB) repair through non-homologous end-joining (NHEJ). It is not fully understood how these proteins are recruited to DSBs. We recently demonstrated radiation-induced chromatin binding of XRCC4 by biochemical fractionation using detergent Nonidet P-40. In the present study, we examined the role of LIG4 in the recruitment of XRCC4/LIG4 complex to chromatin. The chromatin binding of XRCC4 was dependent on the presence of LIG4. The mutations in two BRCT domains (W725R and W893R, respectively) of LIG4 reduced the chromatin binding of LIG4 and XRCC4. The C-terminal fragment of LIG4 (LIG4-CT) without N-terminal catalytic domains could bind to chromatin with XRCC4. LIG4-CT with W725R or W893R mutation could bind to chromatin but could not support the chromatin binding of XRCC4. The ability of C-terminal region of LIG4 to interact with chromatin might provide us with an insight into the mechanisms of DSB repair through NHEJ.

  10. Terminal parent phosphanide and phosphinidene complexes of zirconium(IV)

    Energy Technology Data Exchange (ETDEWEB)

    Stafford, Hannah; Rookes, Thomas M.; Wildman, Elizabeth P.; Wooles, Ashley J.; Liddle, Stephen T. [School of Chemistry, The University of Manchester (United Kingdom); Balazs, Gabor; Scheer, Manfred [Institute of Inorganic Chemistry, University of Regensburg (Germany)

    2017-06-19

    The reaction of [Zr(Tren{sup DMBS})(Cl)] [Zr1; Tren{sup DMBS}=N(CH{sub 2}CH{sub 2}NSiMe{sub 2}Bu{sup t}){sub 3}] with NaPH{sub 2} gave the terminal parent phosphanide complex [Zr(Tren{sup DMBS})(PH{sub 2})] [Zr2; Zr-P=2.690(2) Aa]. Treatment of Zr2 with one equivalent of KCH{sub 2}C{sub 6}H{sub 5} and two equivalents of benzo-15-crown-5 ether (B15C5) afforded an unprecedented example (outside of matrix isolation) of a structurally authenticated transition-metal terminal parent phosphinidene complex [Zr(Tren{sup DMBS})(PH)][K(B15C5){sub 2}] [Zr3; Zr=P=2.472(2) Aa]. DFT calculations reveal a polarized-covalent Zr=P double bond, with a Mayer bond order of 1.48, and together with IR spectroscopic data also suggest an agostic-type Zr..HP interaction [ angle {sub ZrPH}=66.7 ] which is unexpectedly similar to that found in cryogenic, spectroscopically observed phosphinidene species. Surprisingly, computational data suggest that the Zr=P linkage is similarly polarized, and thus as covalent, as essentially isostructural U=P and Th=P analogues. (copyright 2017 Wiley-VCH Verlag GmbH and Co. KGaA, Weinheim)

  11. Control Data's Education Offering: "Plato Would Have Enjoyed PLATO"

    Science.gov (United States)

    Datamation, 1976

    1976-01-01

    Programmed Learning and Teaching Operation (PLATO) distributes instructional materials in the form of text, numbers, animated drawings and other graphics for individualized, self-paced learning. (Author)

  12. From Pericles to Plato

    DEFF Research Database (Denmark)

    Larsen, Øjvind

    2012-01-01

    Plato is normally taken as one of the founders of Western political philosophy, not at least with his Republic. Here, he constructs a hierarchy of forms of governments, beginning with aristocracy at the top as a critical standard for the other forms of governments, and proceeding through timocrac......’ funeral oration is used to show that Pericles presented a democratic political philosophy that can serve as a counterpoint to Plato’s political philosophy in the Republic....

  13. C-Terminal region of DNA ligase IV drives XRCC4/DNA ligase IV complex to chromatin.

    Science.gov (United States)

    Liu, Sicheng; Liu, Xunyue; Kamdar, Radhika Pankaj; Wanotayan, Rujira; Sharma, Mukesh Kumar; Adachi, Noritaka; Matsumoto, Yoshihisa

    2013-09-20

    DNA ligase IV (LIG4) and XRCC4 form a complex to ligate two DNA ends at the final step of DNA double-strand break (DSB) repair through non-homologous end-joining (NHEJ). It is not fully understood how these proteins are recruited to DSBs. We recently demonstrated radiation-induced chromatin binding of XRCC4 by biochemical fractionation using detergent Nonidet P-40. In the present study, we examined the role of LIG4 in the recruitment of XRCC4/LIG4 complex to chromatin. The chromatin binding of XRCC4 was dependent on the presence of LIG4. The mutations in two BRCT domains (W725R and W893R, respectively) of LIG4 reduced the chromatin binding of LIG4 and XRCC4. The C-terminal fragment of LIG4 (LIG4-CT) without N-terminal catalytic domains could bind to chromatin with XRCC4. LIG4-CT with W725R or W893R mutation could bind to chromatin but could not support the chromatin binding of XRCC4. The ability of C-terminal region of LIG4 to interact with chromatin might provide us with an insight into the mechanisms of DSB repair through NHEJ.

  14. Peers on Socrates and Plato

    Science.gov (United States)

    Mackenzie, Jim

    2014-01-01

    There is more to be said about two of the topics Chris Peers addresses in his article "Freud, Plato and Irigaray: A morpho-logic of teaching and learning" (2012, Educational Philosophy and Theory, 44, 760-774), namely the Socratic method of teaching and Plato's stance with regard to women and feminism. My purpose in this article is…

  15. PLATO Sitcom Dialogs for Russian.

    Science.gov (United States)

    Dawson, Clayton; Provenzano, Nolen

    1981-01-01

    Situation comedy (sitcom) dialogs that are included in PLATO lessons for first year Russian students are described. These comprehension exercises make use of both the touch panel and the audio capabilities of PLATO. The sitcom dialogs were written by a native speaker of Russian and are based on the vocabulary in the textbook plus a small number of…

  16. Peers on Socrates and Plato

    Science.gov (United States)

    Mackenzie, Jim

    2014-01-01

    There is more to be said about two of the topics Chris Peers addresses in his article "Freud, Plato and Irigaray: A morpho-logic of teaching and learning" (2012, Educational Philosophy and Theory, 44, 760-774), namely the Socratic method of teaching and Plato's stance with regard to women and feminism. My purpose in this article is…

  17. Phusis and Nomos in Plato

    Directory of Open Access Journals (Sweden)

    Zahra Nouri Sanghdehi

    2017-07-01

    Full Text Available One of the greatest problems in Plato that appears in different forms in his works is the relation of nomos and phusis. This thesis has been in fifth century B.C as the contradiction of phusis and nomos among big thinkers. In this essay, we tried to investigate the relation of phusis and nomos in Plato’s thoughts according to current theories of the contradiction of these in dialogues Gorgias, Republic and Protagoras. Plato tries to minimize consequences of belief to contradiction of phusis and nomos in social and political life by assertion large scale relation between phusis and nomos. Plato depicts the ultimate solution of this problem in Law. There he accounts nomos as raised from phusis that is sub sovereignty of divine. Indeed union of phusis and gods in Plato’s thought is sanction for the identity of phusis and nomos.

  18. What is Plato? Inference and Allusion in Plato's "Sophist."

    Science.gov (United States)

    Quandahl, Ellen

    1989-01-01

    Discusses inference and allusion in the dialogue in Plato's Sophist. Examines the sense in which a locution is used, distinguishing among senses of the verb to be, and sets the ball rolling for the development of logic and the whole metaphysics of categories of being. (RAE)

  19. High-level inhibition of mitochondrial complexes III and IV is required to increase glutamate release from the nerve terminal

    LENUS (Irish Health Repository)

    Kilbride, Sean M

    2011-07-26

    Abstract Background The activities of mitochondrial complex III (ubiquinol-cytochrome c reductase, EC 1.10.2.2) and complex IV (cytochrome c oxidase EC 1.9.3.1) are reduced by 30-70% in Huntington\\'s disease and Alzheimer\\'s disease, respectively, and are associated with excitotoxic cell death in these disorders. In this study, we investigated the control that complexes III and complex IV exert on glutamate release from the isolated nerve terminal. Results Inhibition of complex III activity by 60-90% was necessary for a major increase in the rate of Ca2+-independent glutamate release to occur from isolated nerve terminals (synaptosomes) depolarized with 4-aminopyridine or KCl. Similarly, an 85-90% inhibition of complex IV activity was required before a major increase in the rate of Ca2+-independent glutamate release from depolarized synaptosomes was observed. Inhibition of complex III and IV activities by ~ 60% and above was required before rates of glutamate efflux from polarized synaptosomes were increased. Conclusions These results suggest that nerve terminal mitochondria possess high reserves of complex III and IV activity and that high inhibition thresholds must be reached before excess glutamate is released from the nerve terminal. The implications of the results in the context of the relationship between electron transport chain enzyme deficiencies and excitotoxicity in neurodegenerative disorders are discussed.

  20. Implementation of a terminal switching network supervisor: SAURON, an interactive extension of PACX IV control techniques

    Energy Technology Data Exchange (ETDEWEB)

    Vahle, M O; Tolendino, L F

    1982-04-01

    The rapidly growing number of interactive terminals at Sandia National Laboratories which compete for a limited number of computer ports has given rise to the development of a Terminal Switching Network. This paper describes a minicomputer-based supervisory node which interacts with the switches comprising the network and the operators. The supervisor amplifies the control capabilities of the operators, provides a realtime display of the system status, and records usage statistics.

  1. The Method of Hypothesis in Plato's Philosophy

    Directory of Open Access Journals (Sweden)

    Malihe Aboie Mehrizi

    2016-09-01

    Full Text Available The article deals with the examination of method of hypothesis in Plato's philosophy. This method, respectively, will be examined in three dialogues of Meno, Phaedon and Republic in which it is explicitly indicated. It will be shown the process of change of Plato’s attitude towards the position and usage of the method of hypothesis in his realm of philosophy. In Meno, considering the geometry, Plato attempts to introduce a method that can be used in the realm of philosophy. But, ultimately in Republic, Plato’s special attention to the method and its importance in the philosophical investigations, leads him to revise it. Here, finally Plato introduces the particular method of philosophy, i.e., the dialectic

  2. Plato's Anti-Kohlbergian Program for Moral Education

    Science.gov (United States)

    Jonas, Mark E.

    2016-01-01

    Following Lawrence Kohlberg it has been commonplace to regard Plato's moral theory as "intellectualist", where Plato supposedly believes that becoming virtuous requires nothing other than "philosophical knowledge or intuition of the ideal form of the good". This is a radical misunderstanding of Plato's educational programme,…

  3. THEORY OF LOVE IN PLATO'S PHILOSOPHY

    Directory of Open Access Journals (Sweden)

    ZOHREH MOZAFARI

    2015-01-01

    Full Text Available The article presents a philosophical analysis of the phenomenon of Plato’s love. It is noted that a large number of works are devoted to the philosophy of Plato’s love, but not all aspects of his philosophy are studied, for example the problems of erotosophy of Plato. Phenomenon of love interested philosophers since ancient times. The first attempts to explain the phenomenon of love appeared in ancient times. These attempts were made by ancient philosophers Socrates, Plato and Aristotle. Platonism is a multifaceted teaching; identification of all possibilities of Plato’s erotic philosophy which can supplement other fields of philosophy is important and topical. 

  4. Polynuclear Hydroxido-Bridged Complexes of Platinum(IV) with Terminal Nitrato Ligands.

    Science.gov (United States)

    Vasilchenko, Danila; Berdugin, Semen; Tkachev, Sergey; Baidina, Iraida; Romanenko, Galina; Gerasko, Olga; Korenev, Sergey

    2015-05-18

    For the first time the polynuclear hydroxido-bridged platinum(IV) nitrato complexes with nuclearity higher than two were isolated from nitric acid solutions of [Pt(H2O)2(OH)4] and crystallized as supramolecular compounds of macrocyclic cavitands cucurbit[n]uril (CB[n], n = 6,8) and 18-crown-6 ether: [Pt4(μ3-OH)2(μ2-OH)4(NO3)10]·CB[6]·25H2O (I), [Pt6(μ3-OH)4(μ2-OH)6(NO3)12](NO3)2·CB[8]·50H2O (II), and [H3O⊂18-crown-6]2[Pt2(μ2-OH)2(NO3)8][Pt4(μ3-OH)2(μ2-OH)4(NO3)10] (III). The isolation of the compounds in the single crystalline state allows the determination of the structure of the tetranuclear and hexanuclear complexes [Pt4(μ3-OH)2(μ2-OH)4(NO3)10] and [Pt6(μ3-OH)4(μ2-OH)6(NO3)12](2+), which have been previously unknown in the solid state. Stability of Ptx(OH)y cores of the polynuclear nitrato complexes toward alkaline hydrolysis was verified by (195)Pt NMR spectroscopy. Analysis of (195)Pt NMR spectra of the compound III reveals that addition of every Pt(μ-OH)2Pt ring results in ∼260 ppm downfield shift relative to the mononuclear form, which allows the prediction of signal positions for complexes of higher nuclearity.

  5. Bent and linear Uranium(IV) metallocenes with terminal and bridging cyanide ligands

    Energy Technology Data Exchange (ETDEWEB)

    Maynadie, J.; Berthet, J.C.; Thuery, P.; Ephritikhine, M. [CEA Saclay, DSM, DRECAM, Serv Chim Mol, Lab Claude Frejacques, CNRS URA 331, F-91191 Gif Sur Yvette, (France)

    2007-07-01

    Treatment of Cp{sub 2}{sup *}UI{sub 2} with KCN in thf led to the formation of Cp{sub 2}{sup *}U(CN){sub 2} (2), which further reacted with NR{sub 4}CN to give [Cp{sub 2}{sup *}U(CN){sub 3}][ NR{sub 4}] (R = Et, 3; R = {sup n}Bu, 3') and [Cp{sub 2}{sup *}U(CN){sub 5}][NR{sub 4}]{sub 3} (R = Et, 4; R {sup n}Bu, 4'). While the tri-cyanide 3' adopts the familiar bent sandwich configuration, the penta-cyanide 4 is, after the [Cp{sub 2}{sup *}U(NCMe){sub 5}]{sup 2+} cation, the second example of a linear metallocene resulting from complete saturation of the equatorial girdle. Compound 3' was also obtained by oxidation of the trivalent compound [Cp{sub 2}{sup *}U(CN){sub 3}][N{sup n}Bu{sub 4}]{sub 2}; the rapid and reversible electron transfer between the U(III) and U(IV) complexes was revealed by {sup 1}H NMR spectroscopy. The NMR spectra also revealed that 4 is partially dissociated in thf into 3, providing the first example of an equilibrating couple of bent and linear metallocenes [K = 4.24(4) * 10{sup -5} at 25 C, {delta}H = 199(6) kJ mol{sup -1}, and {delta}S = 586(20) J mol{sup -1} K{sup -1}]. The trinuclear compound [Cp{sub 2}{sup *}UCl{sub 2}({mu}-CN)]{sub 2}Mg(thf){sub 4} (1) and the 2D polymeric complex [Cp{sub 2}{sup *}U(dmf){sub 3}-({mu}-NC){sub 2}(AgI){sub 2}]{sub n} (5), which were obtained during initial attempts on the synthesis of 2-4 and uranium- (V) derivatives, exhibit a bent and linear sandwich structure, respectively. (authors)

  6. Quoting Plato in Porphyrius' Cuestiones homericas

    Directory of Open Access Journals (Sweden)

    Lucía Rodríguez‑Noriega Guillén

    2016-08-01

    Full Text Available This paper studies the quotations of Plato in Porphyry’s Homeric Questions,including their typology (literal quotation, allusion, paraphrase, etc., their beingor not direct citations, their function in the work, and their possible parallels inother authors.

  7. Plato's problem an introduction to mathematical platonism

    CERN Document Server

    Panza, M

    2013-01-01

    What is mathematics about? And how can we have access to the reality it is supposed to describe? The book tells the story of this problem, first raised by Plato, through the views of Aristotle, Proclus, Kant, Frege, Gödel, Benacerraf, up to the most recent debate on mathematical platonism.

  8. The PLATO 2.0 mission

    NARCIS (Netherlands)

    Rauer, H.; et al., [Unknown; Hekker, S.

    2014-01-01

    PLATO 2.0 has recently been selected for ESA’s M3 launch opportunity (2022/24). Providing accurate key planet parameters (radius, mass, density and age) in statistical numbers, it addresses fundamental questions such as: How do planetary systems form and evolve? Are there other systems with planets

  9. Results of the 1975 Delaware PLATO Project.

    Science.gov (United States)

    Hofstetter, Fred T.

    During the Spring semester of 1975, the University of Delaware initiated a PLATO project with the dual purpose of demonstrating how a computer system might function in a university and of evaluating what part such a system might play in the future of the university and its supporting community. The demonstration phase of the project, which…

  10. Socrates, Plato, "Eros" and Liberal Education

    Science.gov (United States)

    McPherran, Mark L.

    2010-01-01

    This paper focuses on the educational method--the "elenchos"--of Plato's Socrates, arguing, against some prominent interpretations, that it is love, both "eros" and "philia", that is the key that links Socrates' philosophy with his education. This analysis, of course, raises some difficult questions regarding the relationship between teacher and…

  11. Plato's Protagoras: Professional Models, Ethical Concerns.

    Science.gov (United States)

    Gregory, Marshall W.

    1983-01-01

    In Plato's model his clear criticism of Protagorean careerism and his negotiation with Socratic radicalism shows he is a centrist cultivating criticism and open discourse. In an age when academe seems to have lost a sense of its identify and function in society, its most enduring contributions are criticism and discourse. (MLW)

  12. CAAPM: Computer-Aided Admissible Probability Measurement on PLATO IV

    Science.gov (United States)

    1976-03-01

    late Renaissance paintings b. Byzantine mosaics c. gothic stained glass 2. Of the following, the watercolorist noted for seascapes is: a...Theodore Gericault *b. Winslow Homer c. Jacob Epstein 3. Which of the following Dutch artists is noted for his genre paint- ings? *a. Jan Steen b. Jan

  13. What scientists can learn from Plato's Symposium

    Science.gov (United States)

    van Emmerik, Tim

    2015-04-01

    Conferences and scientific meetings are as old as science itself. The ancient Greeks where (in)famous for organizing so-called symposiums. During a symposium (from Greek, drinking together), attendees followed a program that contained both social and scientific aspects, focused around a certain topic. Whilst drinking and eating, all participants were expected to share their vision on the topic of interest by giving an oral presentation. The goal of these meetings was to arrive at a new common understanding and to come closer to the truth. Plato et al. knew very well how to organize an effective scientific conference, which should make use overthink the way we are organizing present-day conferences. Scientific meetings aim to connect researchers, share research and unravel the truth. The question is now: how do we get this done effectively? Plato knew that discussing science with strangers is difficult and he believed that talking about heavy matter could be done best when combined with social events. What if we try to go back to the times of Plato and model our conferences after the ancient symposiums? We might drop laying on couches and covering ourselves in ivy and flowers. However, a mix of social and scientific events will contribute to achieving the ultimate goal of why scientists go to conferences: to connect, to share and to unravel the truth.

  14. Project Termination Report. Title IV-C Classroom Management Project. ESEA Title IV-C, August 29, 1981 - September 30, 1982.

    Science.gov (United States)

    Halasa, Ofelia; Theus, Frank

    This report provides a summary description of the Title IV-C Classroom Management Project conducted in the Cleveland (Ohio) Public Schools. The purpose of this project was to develop and pilot test a resource handbook designed to improve elementary and secondary school teachers' ability to organize and manage their classrooms. The development of…

  15. From Plato to Orwell: Utopian Rhetoric in a Dystopian World.

    Science.gov (United States)

    Deatherage, Scott

    Plato's "Republic" and George Orwell's "1984" both posit visionary worlds, one where humans are virtuous and understand what Plato refers to as "the Good," and the other where citizens are pawns of a government which uses language as a form of tyranny and control. Despite these overarching differences in philosophical…

  16. A Summary of Plato Curriculum and Research Materials.

    Science.gov (United States)

    Lyman, Elisabeth R.

    PLATO (programmed Logic for Automatic Teaching Operations) is a computer-based teaching system which was developed in the Coordinated Science Laboratory at the University of Illinois to explore the possibilities of automation in individual instruction. The history of the PLATO program is summarized here, along with a list of courses which used…

  17. From Plato to Orwell: Utopian Rhetoric in a Dystopian World.

    Science.gov (United States)

    Deatherage, Scott

    Plato's "Republic" and George Orwell's "1984" both posit visionary worlds, one where humans are virtuous and understand what Plato refers to as "the Good," and the other where citizens are pawns of a government which uses language as a form of tyranny and control. Despite these overarching differences in philosophical…

  18. Plato the Pederast: Rhetoric and Cultural Procreation in the Dialogues.

    Science.gov (United States)

    Ervin, Elizabeth

    1993-01-01

    Examines Plato's Dialogues by reading them through two cultural lenses: the role of eros in classical Greece and its analogous relationship to language and rhetoric; and the educational function of eros within the ancient institution of pederasty. Shows how the cultural values of ancient Greece manifested themselves in Plato's erotic educational…

  19. Plato's Philosophy of Education and the Common Core Debate

    Science.gov (United States)

    Murphy, Madonna M.

    2015-01-01

    This paper examines Plato's Philosophy of Education asking what he would say about the current Common Core initiative which is to better help students to become college and career ready. Plato would be in favor of the common core in as much as the standards are tied to specific skills needed in various career jobs as he was a proponent of…

  20. Fourth Summative Report of the Delaware PLATO Project.

    Science.gov (United States)

    Hofstetter, Fred T.

    A brief history of the Delaware PLATO project and descriptions of new developments in facilities, applications, user services, research, evaluation, and courseware produced since the Third Summative Report (1978) are provided, as well as an overview of PLATO applications at the University of Delaware. Sample lessons, illustrations, and activity…

  1. Fifth Summative Report of the Delaware PLATO Project.

    Science.gov (United States)

    Hofstetter, Fred T.

    A brief history of the Delaware PLATO project and descriptions of the new developments in facilities, applications, user services, research, evaluation, and courseware produced since the Fourth Summative Report (1979) are provided, as well as an overview of PLATO applications at the University of Delaware. Sample lessons, illustrations, and…

  2. Third Summative Report of the Delaware PLATO Project.

    Science.gov (United States)

    Hofstetter, Fred T.

    Descriptions of new developments in the areas of facilities, applications, user services, support staff, research, evaluation, and courseware production since the Second Summative Report (1977) are provided, as well as a summative overview of PLATO applications at the University of Delaware. Through the purchase of its own PLATO system, this…

  3. Plato's ghost the modernist transformation of mathematics

    CERN Document Server

    Gray, Jeremy

    2008-01-01

    Plato's Ghost is the first book to examine the development of mathematics from 1880 to 1920 as a modernist transformation similar to those in art, literature, and music. Jeremy Gray traces the growth of mathematical modernism from its roots in problem solving and theory to its interactions with physics, philosophy, theology, psychology, and ideas about real and artificial languages. He shows how mathematics was popularized, and explains how mathematical modernism not only gave expression to the work of mathematicians and the professional image they sought to create for themselves, but how modernism also introduced deeper and ultimately unanswerable questions

  4. Pemikiran Epistemologi Barat: dari Plato Sampai Gonseth

    Directory of Open Access Journals (Sweden)

    Nunu Burhanuddin

    2015-06-01

    Full Text Available This paper riviewing the Western epistemology thought. The theme focuses on Plato to Gonseth. The Epistemology that referred in this article, is to think about "how humans acquire knowledge?". From this then appear four types of sect modern western epistemology thought, namely: sect of empiricism, rationalism sect, kantinian sect, sect of positivism. Furthermore, the social positivism sciences developed by Comte leaves serious problems associated with the loss of the role of the subject. This problem being the background of epistemology philosophy appears that by Emund Husserl developed through the phenomenology, Habermas through hermeneutics, and Ferdinand Gonseth through critical theory.

  5. The PLATO 2.0 Mission

    CERN Document Server

    Rauer, H; Aerts, C; Appourchaux, T; Benz, W; Brandeker, A; Christensen-Dalsgaard, J; Deleuil, M; Gizon, L; Güdel, M; Janot-Pacheco, E; Mas-Hesse, M; Pagano, I; Piotto, G; Pollacco, D; Santos, N C; Smith, A; -C., J; Suárez,; Szabó, R; Udry, S; Adibekyan, V; Alibert, Y; Almenara, J -M; Amaro-Seoane, P; Eiff, M Ammler-von; Antonello, E; Ball, W; Barnes, S; Baudin, F; Belkacem, K; Bergemann, M; Birch, A; Boisse, I; Bonomo, A S; Borsa, F; Brandão, I M; Brocato, E; Brun, S; Burleigh, M; Burston, R; Cabrera, J; Cassisi, S; Chaplin, W; Charpinet, S; Chiappini, C; Csizmadia, Sz; Cunha, M; Damasso, M; Davies, M B; Deeg, H J; Fialho, F de Oliveira; DÍaz, R F; Dreizler, S; Dreyer, C; Eggenberger, P; Ehrenreich, D; Eigmüller, P; Erikson, A; Farmer, R; Feltzing, S; Figueira, P; Forveille, T; Fridlund, M; García, R; Giuffrida, G; Godolt, M; da Silva, J Gomes; Goupil, M -J; Granzer, T; Grenfell, J L; Grotsch-Noels, A; Günther, E; Haswell, C A; Hatzes, A P; Hébrard, G; Hekker, S; Helled, R; Heng, K; Jenkins, J M; Khodachenko, M L; Kislyakova, K G; Kley, W; Kolb, U; Krivova, N; Kupka, F; Lammer, H; Lanza, A F; Lebreton, Y; Magrin, D; Marcos-Arenal, P; Marrese, P M; Marques, J P; Martins, J; Mathis, S; Mathur, S; Messina, S; Miglio, A; Montalban, J; Montalto, M; Monteiro, M J P F G; Moradi, H; Moravveji, E; Mordasini, C; Morel, T; Mortier, A; Nascimbeni, V; Nielsen, M B; Noack, L; Norton, A J; Ofir, A; Oshagh, M; Ouazzani, R -M; Pápics, P; Parro, V C; Petit, P; Plez, B; Poretti, E; Quirrenbach, A; Ragazzoni, R; Raimondo, G; Rainer, M; Reese, D R; Redmer, R; Reffert, S; Rojas-Ayala, B; Roxburgh, I W; Solanki, S K; Salmon, S; Santerne, A; Schneider, J; Schou, J; Schuh, S; Schunker, H; Silva-Valio, A; Silvotti, R; Skillen, I; Snellen, I; Sohl, F; Sousa, A S; Sozzetti, A; Stello, D; Strassmeier, K G; Švanda, M; Szabó, G M; Tkachenko, A; Valencia, D; van Grootel, V; Vauclair, S D; Ventura, P; Wagner, F W; Walton, N A; Weingrill, J; Werner, S C; Wheatley, P J; Zwintz, K

    2013-01-01

    PLATO 2.0 is a mission candidate for ESA's M3 launch opportunity (2022/24). It addresses fundamental questions such as: How do planetary systems form and evolve? Are there other systems with planets like ours, able to develop life? The PLATO 2.0 instrument consists of 34 small aperture telescopes providing a wide field-of-view and a large photometric magnitude range. It targets bright stars in wide fields to detect and characterize planets down to Earth-size by photometric transits, whose masses can then be determined by ground-based radial-velocity follow-up measurements. Asteroseismology will be performed for stars <=11mag to obtain highly accurate stellar parameters, including masses and ages. The combination of bright targets and asteroseismology results in high accuracy for the bulk planet parameters: 2%, 4-10% and 10% for planet radii, masses and ages, respectively. The foreseen baseline observing strategy includes two long pointings (2-3 years) to detect and bulk characterize planets reaching into t...

  6. Plato on Metaphysical Explanation: Does 'Participating' Mean Nothing?

    Directory of Open Access Journals (Sweden)

    Christine J. Thomas

    2014-12-01

    Full Text Available According to Aristotle, Plato's efforts at metaphysical explanation not only fail, they are nonsensical. In particular, Plato's appeals to Forms as metaphysically explanatory of the sensibles that participate in them is "empty talk" since "'participating' means nothing" (Met. 992a28-9. I defend Plato against Aristotle's charge by identifying a particular, substantive model of metaphysical predication as the favored model of Plato's late ontology. The model posits two basic metaphysical predication relations: self-predication and participation. In order to understand the participation relation, it is important first to understand how Plato's Forms are self-predicative paradigms. According to the favored model, Forms are self-predicative paradigms insofar as they are ideal, abstract encoders of structural essences. Sensibles participate in Forms by exemplifying the structures encoded in the Forms. Given plausible conditions on metaphysical explanation, Plato's appeals to abstract Forms as metaphysically explanatory of sensibles is a reasonable competitor for Aristotle's appeals to natural, substantial forms. At the very least, Plato's appeals to a participation relation are not empty.

  7. Technology validation of the PLATO CCD at ESA

    Science.gov (United States)

    Prod'homme, Thibaut; Verhoeve, Peter; Beaufort, Thierry; Duvet, Ludovic; Lemmel, Frederic; Smit, Hans; Blommaert, Sander; Oosterbroek, Tim; van der Luijt, Cornelis; Visser, Ivo; Heijnen, Jerko; Butler, Bart

    2016-07-01

    PLATO { PLAnetary Transits and Oscillations of stars { is the third medium-class mission to be selected in the European Space Agency (ESA) Science and Robotic Exploration Cosmic Vision programme. Due for launch in 2025, the payload makes use of a large format (8 cm x 8 cm) Charge-Coupled Devices (CCDs) the e2v CCD270 operated at 4 MHz. The manufacture of such large device in large quantity constitutes an unprecedented effort. To de-risk the PLATO CCD procurement and aid the mission definition process, ESA's Payload Technology Validation team is characterizing the electro-optical performance of a number of PLATO devices before and after proton irradiation.

  8. A scientific approach to Plato's Atlantis

    Directory of Open Access Journals (Sweden)

    Massimo Rapisarda

    2015-09-01

    Full Text Available The myth of Atlantis is hard to die. This attempt to use scientific evidence to give it the final smash ends up with the doubt that it might not be totally unsubstantiated. The time of the supposed existence of Atlantis (around twelve thousand years ago was, in fact, characterized by technological revolutions, acknowledged by archaeology, and abrupt climate changes, documented by geology. In principle, it cannot therefore be ruled out that some of those dramatic events left a memory, later used by Plato as a basis for its tale. The climate changes involved the majority of the northern hemisphere, thus all the ancient civilizations (Egyptian, Mesopotamian, Indian and Chinese could have preserved reminiscence, but it is clear that the events occurring closer to Greece would have been more accessible to Plato. Among the Mediterranean sites that experienced the cataclysms of the beginning of the Holocene, a good candidate to host a primordial civilization might have been the archipelago then existing in the Strait of Sicily, a natural maritime link between Tunisia and Italy, prized by the presence of an obsidian source at Pantelleria. Eleven thousand five hundred years ago, a sudden sea level rise erased the archipelago, submerging the possible settlements, but Pantelleria obsidian ores are still there and could provide a significant clue. In fact, the potential discovery of artefacts, originating from a source now submerged by the sea level rise, would imply that the collection of the mineral took place when it was still emerged, namely at the time of Atlantis. Even if such discovery would not be sufficient to prove the existence of the mythical island, it would be enough to shake up the timeline of the human occupation in the region.

  9. The PCP SYS IV Management System: Educational Overview.

    Science.gov (United States)

    Siegel, Martin A.; Davis, Dennis M.

    This paper describes the structure and function of the SYS IV PLATO Curriculum Project's (PCP) computer-based management system and justifies the system design. A consideration of features most critical in the design of management systems provides the context for a discussion of specific SYS IV features, which include its ability to deliver any…

  10. The PCP SYS IV Management System: Technical Overview.

    Science.gov (United States)

    Bryan, John T.; Felty, J. Michael

    This paper is the second in a three-part series on SYS IV, an instructional management system developed by the PLATO Curriculum Project (PCP) that incorporates some of the features of the previous SYS systems. Focus is primarily on the new features that make the system unique. Following a brief background section explaining the purpose of SYS IV,…

  11. Intra-Socratic Polemics: The Symposia of Plato and Xenophon

    Directory of Open Access Journals (Sweden)

    Gabriel Danzig

    2010-11-01

    Full Text Available Textual relationships between the two Symposia suggest that Xenophon wrote first, prompting Plato to write Socrates' critique of Phaedrus, to which Xenophon responded by appending his ch. 8.

  12. Rationality and Motivation: Moral Psychology in Plato's Socratic Dialogues

    OpenAIRE

    Ivars Neiders

    2011-01-01

    "Rationality and Motivation: Moral Psychology in Plato's Socratic Dialogues" Annotation The dissertation "Rationality and Motivation: Moral Psychology in Plato's Socratic Dialogues" is a philosophical study of Socratic views in moral psychology. Particular attention is paid to what the author calls (1) Doxastic competence and (2) Orectic competence. It is argued that according to Socrates these two different epistemic relations are important aspects of our self-understanding. The doxast...

  13. Synthesis and characterization of an f-block terminal parent imido [U═NH] complex: a masked uranium(IV) nitride.

    Science.gov (United States)

    King, David M; McMaster, Jonathan; Tuna, Floriana; McInnes, Eric J L; Lewis, William; Blake, Alexander J; Liddle, Stephen T

    2014-04-16

    Deprotonation of [U(Tren(TIPS))(NH2)] (1) [Tren(TIPS) = N(CH2CH2NSiPr(i)3)3] with organoalkali metal reagents MR (M = Li, R = Bu(t); M = Na-Cs, R = CH2C6H5) afforded the imido-bridged dimers [{U(Tren(TIPS))(μ-N[H]M)}2] [M = Li-Cs (2a-e)]. Treatment of 2c (M = K) with 2 equiv of 15-crown-5 ether (15C5) afforded the uranium terminal parent imido complex [U(Tren(TIPS))(NH)][K(15C5)2] (3c), which can also be viewed as a masked uranium(IV) nitride. The uranium-imido linkage was found to be essentially linear, and theoretical calculations suggested σ(2)π(4) polarized U-N multiple bonding. Attempts to oxidize 3c to afford the neutral uranium terminal parent imido complex [U(Tren(TIPS))(NH)] (4) resulted in spontaneous disproportionation to give 1 and the uranium-nitride complex [U(Tren(TIPS))(N)] (5); this reaction is a new way to prepare the terminal uranium-nitride linkage and was calculated to be exothermic by -3.25 kcal mol(-1).

  14. What Plato and Murdoch Think About Love

    Directory of Open Access Journals (Sweden)

    Shadi Shakouri

    2012-07-01

    Full Text Available There are many interpretations of love and lots of scholars write and talk on love; however, what exactly is the meaning of love? Iris Murdoch’s works are an accumulation of emotional relationships and feelings of love. Her great subject is love, both sexual and non-sexual, and her characters are the portrayal of a small group of people caught up in convoluted ties of love and hate, with Eros ruling over them (Cohen 22. Murdoch was one of the most respected British writers and philosophers of the second half of the twentieth century and, of course, the postwar period. In Murdoch’s novels, love is one of the central themes—marriage, as the institution of love, more often binds than frees. Her characters are mainly ego-centric people who struggle to love and are often overwhelmed by the factor of self-obsession, jealousy, ambition, fascination with suffering and charismatic power. They are absolutely ordinary people with a consuming demand for love, and mental and physical exile. Murdoch was inspired by Plato’s ideas in many ways. Like art, here again Plato’s idea of love is more skeptical than Murdoch’s, whereas Murdoch kept it only as a way to the Good, creation, and happiness. Murdoch and Plato saw love more as a Freudian concept, the Eros, the word that comes from the name of the first Greek god of love. Both the philosophers, Plato and Murdoch, believed that this erotic longing and desires revived by Eros can led to a new direction, a way toward virtue and truth. Her protagonist or marginalized characters are usually tackling it with either vulgarity or the heavenly, which results in creation, art or salvation. Murdoch, as a major moral philosopher, usually grasps the chances to encapsulate her moral visions in her works, and created novels that should be counted as meditations on human love and goodness. Keywords: Eros, erotic love and real artwork, moral philosopher, The Black Prince

  15. A novel COL4A1 frameshift mutation in familial kidney disease: the importance of the C-terminal NC1 domain of type IV collagen

    Science.gov (United States)

    Gale, Daniel P.; Oygar, D. Deren; Lin, Fujun; Oygar, P. Derin; Khan, Nadia; Connor, Thomas M.F.; Lapsley, Marta; Maxwell, Patrick H.; Neild, Guy H.

    2016-01-01

    Background Hereditary microscopic haematuria often segregates with mutations of COL4A3, COL4A4 or COL4A5 but in half of families a gene is not identified. We investigated a Cypriot family with autosomal dominant microscopic haematuria with renal failure and kidney cysts. Methods We used genome-wide linkage analysis, whole exome sequencing and cosegregation analyses. Results We identified a novel frameshift mutation, c.4611_4612insG:p.T1537fs, in exon 49 of COL4A1. This mutation predicts truncation of the protein with disruption of the C-terminal part of the NC1 domain. We confirmed its presence in 20 family members, 17 with confirmed haematuria, 5 of whom also had stage 4 or 5 chronic kidney disease. Eleven family members exhibited kidney cysts (55% of those with the mutation), but muscle cramps or cerebral aneurysms were not observed and serum creatine kinase was normal in all individuals tested. Conclusions Missense mutations of COL4A1 that encode the CB3 [IV] segment of the triple helical domain (exons 24 and 25) are associated with HANAC syndrome (hereditary angiopathy, nephropathy, aneurysms and cramps). Missense mutations of COL4A1 that disrupt the NC1 domain are associated with antenatal cerebral haemorrhage and porencephaly, but not kidney disease. Our findings extend the spectrum of COL4A1 mutations linked with renal disease and demonstrate that the highly conserved C-terminal part of the NC1 domain of the α1 chain of type IV collagen is important in the integrity of glomerular basement membrane in humans. PMID:27190376

  16. Reversing Plato’s Anti-Democratism: Castoriadis’ “Quirky” Plato

    OpenAIRE

    Wendy C. Hamblet

    2008-01-01

    This paper considers the conflicting "loves" of Cornelius Castoriadis--his love for the ancients, and especially Plato, and for the common person of the demos. A detailed study of Castoriadis' analysis of Plato's Statesman exposes that Castoriadis attempts to resolve the paradox by rereading Plato as a radical democrat. I argue that this unorthodox reading is at best "quirky, " (a charge Castoriadis levels at Plato) at worst a groundless sophism. However, I conjecture that Castoriadis' readin...

  17. Eugenics concept: from Plato to present.

    Science.gov (United States)

    Güvercin, C H; Arda, B

    2008-01-01

    All prospective studies and purposes to improve cure and create a race that would be exempt of various diseases and disabilities are generally defined as eugenic procedures. They aim to create the "perfect" and "higher" human being by eliminating the "unhealthy" prospective persons. All of the supporting actions taken in order to enable the desired properties are called positive eugenic actions; the elimination of undesired properties are defined as negative eugenics. In addition, if such applications and approaches target the public as a whole, they are defined as macro-eugenics. On the other hand, if they only aim at individuals and/or families, they are called micro-eugenics. As generally acknowledged, Galton re-introduced eugenic proposals, but their roots stretch as far back as Plato. Eugenic thoughts and developments were widely accepted in many different countries beginning with the end of the 19th to the first half of the 20th centuries. Initially, the view of negative eugenics that included compulsory sterilizations of handicapped, diseased and "lower" classes, resulted in tens of thousands being exterminated especially in the period of Nazi Germany. In the 1930s, the type of micro positive eugenics movement found a place within the pro-natalist policies of a number of countries. However, it was unsuccessful since the policy was not able to become effective enough and totally disappeared in the 1960s. It was no longer a fashionable movement and left a deep impression on public opinion after the long years of war. However, developments in genetics and its related fields have now enabled eugenic thoughts to reappear under the spotlight and this is creating new moral dilemmas from an ethical perspective.

  18. Positure in Plato's Laws: An Introduction to Figuration on Civic Education

    Science.gov (United States)

    Hall, Joshua M.

    2016-01-01

    Purpose: The aim of the research was to determine the benefits of applying the new Figuration philosophy of dance, based in part on Plato, to civic education. Design/methodology: A close phenomenological reading of Plato's "The Laws," with a strategic focus on its account of the concept of posture. Findings: Plato considers posture to be…

  19. Plato's Cosmic Theology: A Rationale for a Polytheistic Astrology?

    Science.gov (United States)

    Henriques, André

    2015-05-01

    Plato's cosmology influenced classical astronomy and religion, but was in turn influenced by the polytheistic context of its time. Throughout his texts, including the cosmological treatise Timaeus, and the discussions on the soul in the Phaedrus, Plato (c.428-c.348 BC) established what can be generalised as Platonic cosmological thought. An understanding of the philosophical and mythical levels of Platonic thought can provide a rationale for polytheistic and astrological worldviews, pointing to some cosmological continuity, alongside major shifts, from ancient Greek religion to the astrological thought of ancient astronomers such as Claudius Ptolemy.

  20. ESA's CCD test bench for the PLATO mission

    Science.gov (United States)

    Beaufort, Thierry; Duvet, Ludovic; Bloemmaert, Sander; Lemmel, Frederic; Prod'homme, Thibaut; Verhoeve, Peter; Smit, Hans; Butler, Bart; van der Luijt, Cornelis; Heijnen, Jerko; Visser, Ivo

    2016-08-01

    PLATO { PLAnetary Transits and Oscillations of stars { is the third medium-class mission to be selected in the European Space Agency (ESA) Science and Robotic Exploration Cosmic Vision programme. Due for launch in 2025, the payload makes use of a large format (8 cm x 8 cm) Charge-Coupled Devices (CCDs), the e2v CCD270 operated at 4 MHz and at -70 C. To de-risk the PLATO CCD qualification programme initiated in 2014 and support the mission definition process, ESA's Payload Technology Validation section from the Future Missions Office has developed a dedicated test bench.

  1. Alternative communication network designs for an operational Plato 4 CAI system

    Science.gov (United States)

    Mobley, R. E., Jr.; Eastwood, L. F., Jr.

    1975-01-01

    The cost of alternative communications networks for the dissemination of PLATO IV computer-aided instruction (CAI) was studied. Four communication techniques are compared: leased telephone lines, satellite communication, UHF TV, and low-power microwave radio. For each network design, costs per student contact hour are computed. These costs are derived as functions of student population density, a parameter which can be calculated from census data for one potential market for CAI, the public primary and secondary schools. Calculating costs in this way allows one to determine which of the four communications alternatives can serve this market least expensively for any given area in the U.S. The analysis indicates that radio distribution techniques are cost optimum over a wide range of conditions.

  2. Goodpasture syndrome. Localization of the epitope for the autoantibodies to the carboxyl-terminal region of the alpha 3(IV) chain of basement membrane collagen.

    Science.gov (United States)

    Kalluri, R; Gunwar, S; Reeders, S T; Morrison, K C; Mariyama, M; Ebner, K E; Noelken, M E; Hudson, B G

    1991-12-15

    The autoantibodies of patients with Goodpasture syndrome are primarily targeted to the noncollagenous (NC1) domain of the alpha 3(IV) chain of basement membrane collagen (Saus, J., Wieslander, J., Langeveld, J. P. M., Quinones, S., and Hudson, B. G. (1988) J. Biol. Chem. 263, 13374-13380). In the present study, the location of the Goodpasture epitope in human alpha 3NC1 was determined, and its structure was partially characterized. This was achieved by identification of regions of alpha 3NC1 which are candidates for the epitope and which are structurally unique among the five known homologous NC1 domains (alpha 1-alpha 5); amino acids that are critical for Goodpasture antibody binding, by selective chemical modifications; and regions that are critical for Goodpasture antibody binding, by synthesis of 12 alpha 3NC1 peptides and measurement of their antibody binding capacity. The carboxyl-terminal region, residues 198-233, was identified as the most likely region for the epitope. By experiment, lysine and cysteine were identified as critical amino acids for antibody binding. Three synthetic peptides were found to inhibit Goodpasture antibody binding to alpha 3NC1 markedly: a 36-mer (residues 198-233), a 12-mer (residues 222-233), and a 5-mer (residues 229-233). Together, these results strongly indicate that the Goodpasture epitope is localized to the carboxyl-terminal region of alpha 3NC1, encompassing residues 198-233 as the primary antibody interaction site and that its structure is discontinuous. These findings provide a conceptual framework for future studies to elucidate a more complete epitope structure by sequential replacement of residues encompassing the epitope using cDNA expression products and peptides synthesized chemically.

  3. A Data Bank Experience on the PLATO System.

    Science.gov (United States)

    Schwab, Wallace; St-Denis, Richard

    1980-01-01

    Current theories on terminology and lexicography which underlie the logical components of the terminology bank set up on the PLATO system and established standards are briefly presented. The units that were essential to developing the bank are discussed. References are listed. (Author)

  4. Plato and Play: Taking Education Seriously in Ancient Greece

    Science.gov (United States)

    D'Angour, Armand

    2013-01-01

    In this article, the author outlines Plato's notions of play in ancient Greek culture and shows how the philosopher's views on play can be best appreciated against the background of shifting meanings and evaluations of play in classical Greece. Play--in various forms such as word play, ritual, and music--proved central to the development of…

  5. Stonecutter Mills, Inc., Isothermal Community College. PLATO Evaluation Series.

    Science.gov (United States)

    Sherman, Greg

    Stonecutter Mills, Inc., is a textile manufacturing company with a major production facility in Spindale, North Carolina. In the past few years, Stonecutter Mills employees have been given an opportunity to spend up to 2 hours a week on company time to participate in PLATO-supported learning at Isothermal Community College. Employees could choose…

  6. Future development of the PLATO Observatory for Antarctic science

    Science.gov (United States)

    Ashley, Michael C. B.; Bonner, Colin S.; Everett, Jon R.; Lawrence, Jon S.; Luong-Van, Daniel; McDaid, Scott; McLaren, Campbell; Storey, John W. V.

    2010-07-01

    PLATO is a self-contained robotic observatory built into two 10-foot shipping containers. It has been successfully deployed at Dome A on the Antarctic plateau since January 2008, and has accumulated over 730 days of uptime at the time of writing. PLATO provides 0.5{1kW of continuous electrical power for a year from diesel engines running on Jet-A1, supplemented during the summertime with solar panels. One of the 10-foot shipping containers houses the power system and fuel, the other provides a warm environment for instruments. Two Iridium satellite modems allow 45 MB/day of data to be transferred across the internet. Future enhancements to PLATO, currently in development, include a more modular design, using lithium iron-phosphate batteries, higher power output, and a light-weight low-power version for eld deployment from a Twin Otter aircraft. Technologies used in PLATO include a CAN (Controller Area Network) bus, high-reliability PC/104 com- puters, ultracapacitors for starting the engines, and fault-tolerant redundant design.

  7. Pursuing the Good, Ethics and Metaphysics in Plato s Republic

    Institute of Scientific and Technical Information of China (English)

    Douglas; Cairns; Fritz-Gregor; Herrmann; Terry; Penner

    2008-01-01

    ‘Pursuing the good’ is an old subject in both social history of ancient Greece and Greek philosophy studies. There is hardly anything new when we talk about virtue or morality in the time of Plato and Aristotle. In the area of Greek history, many books and articles on or relevant to that

  8. Eschatological narrative in Plato: between logos and myth

    Directory of Open Access Journals (Sweden)

    Francesc Casadesús Bordoy

    2016-08-01

    Full Text Available In his dialogues, Plato frequently resorted to alternate and intertwine his dialectic expositions with images and allegories, aiming to illustrate his arguments. This paper analyses in detail his use of the opposition between logos and myth tointroduce his descriptions of Hades

  9. Go Tell Alcibiades: Tragedy, Comedy, and Rhetoric in Plato's "Symposium"

    Science.gov (United States)

    Crick, Nathan; Poulakos, John

    2008-01-01

    Plato's "Symposium" is a significant but neglected part of his elaborate and complex attitude toward rhetoric. Unlike the intellectual discussion of the "Gorgias" or the unscripted conversation of the "Phaedrus," the "Symposium" stages a feast celebrating and driven by the forces of "Eros." A luxuriously stylish performance rather than a rational…

  10. The Cost of PLATO in a University Environment.

    Science.gov (United States)

    Hofstetter, Fred T.

    1983-01-01

    This analysis of the cost-effectiveness of the University of Delaware's own PLATO system discusses the initial expense of acquiring the system, decreases in unit cost as number of users increased, capital investment in hardware, expenditures and funding sources, comparisons of actual and projected costs, and benefits of individualized instruction.…

  11. Second Summative Report of the Delaware PLATO Project.

    Science.gov (United States)

    Hofstetter, Fred T.

    Begun on an experimental basis in March 1975, the ongoing PLATO project at the University of Delaware has become an established part of the University's academic program. This descriptive report is divided into three sections: (1) project history and development, including organization, utilization, instructor and author training, and projections…

  12. Dodecahedrane—The chemical transliteration of Plato's universe (A Review)

    Science.gov (United States)

    Paquette, Leo A.

    1982-07-01

    The development of chemical interest in three of Plato's five convex polyhedra is described from an historical perspective. The successful synthesis of 1,16-dimethyldodecahedrane and its structural characteristics are outlined. Finally, an account of recent work leading to the still more aesthetically appealing and ultrasymmetric parent dodecahedrane is given.

  13. Arete and physics: The lesson of Plato's "Timaeus"

    Science.gov (United States)

    Wolfe, John R.

    Plato's Timaeus is traditionally read as a work dedicated to the sole purpose of describing the origin and nature of the cosmos, as a straightforward attempt by Plato to produce a peri phuseos treatise. In accord with this reading, the body of Timaeus' monologue is then seen as nothing more than an attempt by Plato to convey his own cosmological doctrines. I propose an alternative to the view that the Timaeus is nothing more than a textbook of Platonic physics. The Timaeus is rather squarely focused on the human being, in her moral and political dimensions, and on her relation to the natural world as a whole. Ultimately, this account of the human being is intended to provide part of the answer to the question of how society can produce good citizens and leaders, and thus serves to provide a theoretical basis for the practices of paideia. When viewed in this light many of the curious features of the Timaeus appear less strange. The various parts of the dialogue: the dramatic introduction, Critias' tale of the Ancient Athenians, and Timaeus' monologue can be seen as each contributing to an investigation of a single topic. It further allows us to understand why Plato chooses to employ Timaeus the Locrian as the principle speaker of the dialogue rather than Socrates. Finally, when read in this way, the Timaeus no longer appears as an outlier in the Platonic corpus, as a work devoted to a radically different subject matter than the rest of his writings. It can be seen as dedicated to the same issues which preoccupied Plato throughout his entire life, as about the determination of the best life and providing the tools with which to realize it.

  14. The PCP SYS IV Management System: Implementation and Training Overview.

    Science.gov (United States)

    Silver, Dorothy Z.; Clapp, Elizabeth J.

    This is the final paper in a series of three on SYS IV, a computer-based management system developed by the PLATO Curriculum Project (PCP) which tests students, routes students to lessons, stores detailed records of online student activity, and keeps summary records of student activities. An introduction describes how the system simultaneously…

  15. Teaching Early Mathematics with PLATO[R] Software: An Overview of the New PLATO Elementary Mathematics Curricula and How To Use Them. Technical Paper.

    Science.gov (United States)

    Quinn, Bill; Foshay, Rob; Morris, Barbara

    The "PLATO[R] Math Expeditions" and "PLATO[R] Projects for the Real World" curricula are designed to implement effective, research-based instructional practices. "Math Expeditions" is designed to give elementary grade users the mathematics skills and practice needed to solve real-life problems. Across the eight…

  16. The C-Terminal Module IV of Connective Tissue Growth Factor, Through EGFR/Nox1 Signaling, Activates the NF-κB Pathway and Proinflammatory Factors in Vascular Smooth Muscle Cells

    Science.gov (United States)

    Rodrigues-Diez, Raúl R.; Orejudo, Macarena; Rodrigues-Diez, Raquel; Briones, Ana Maria; Bosch-Panadero, Enrique; Kery, Gyorgy; Pato, Janos; Ortiz, Alberto; Salaices, Mercedes; Egido, Jesus; Ruiz-Ortega, Marta

    2015-01-01

    Abstract Aims: Connective tissue growth factor (CTGF/CCN2) is a developmental gene upregulated in pathological conditions, including cardiovascular diseases, whose product is a matricellular protein that can be degraded to biologically active fragments. Among them, the C-terminal module IV [CCN2(IV)] regulates many cellular functions, but there are no data about redox process. Therefore, we investigated whether CCN2(IV) through redox signaling regulates vascular responses. Results: CCN2(IV) increased superoxide anion (O2•−) production in murine aorta (ex vivo and in vivo) and in cultured vascular smooth muscle cells (VSMCs). In isolated murine aorta, CCN2(IV), via O2•−, increased phenylephrine-induced vascular contraction. CCN2(IV) in vivo regulated several redox-related processes in mice aorta, including increased nonphagocytic NAD(P)H oxidases (Nox)1 activity, protein nitrosylation, endothelial dysfunction, and activation of the nuclear factor-κB (NF-κB) pathway and its related proinflammatory factors. The role of Nox1 in CCN2(IV)-mediated vascular responses in vivo was investigated by gene silencing. The administration of a Nox1 morpholino diminished aortic O2•− production, endothelial dysfunction, NF-κB activation, and overexpression of proinflammatory genes in CCN2(IV)-injected mice. The link CCN2(IV)/Nox1/NF-κB/inflammation was confirmed in cultured VSMCs. Epidermal growth factor receptor (EGFR) is a known CCN2 receptor. In VSMCs, CCN2(IV) activates EGFR signaling. Moreover, EGFR kinase inhibition blocked vascular responses in CCN2(IV)-injected mice. Innovation and Conclusion: CCN2(IV) is a novel prooxidant factor that in VSMCs induces O2•− production via EGFR/Nox1 activation. Our in vivo data demonstrate that CCN2(IV) through EGFR/Nox1 signaling pathway induces endothelial dysfunction and activation of the NF-κB inflammatory pathway. Therefore, CCN2(IV) could be considered a potential therapeutic target for redox-related cardiovascular

  17. THE JOURNEY OF TRUTH: FROM PLATO TO ZOLA

    Directory of Open Access Journals (Sweden)

    Ribut Basuki

    1999-01-01

    Full Text Available Western theater theory and criticism is generally considered to be set forth by the Greeks. Plato was "the first theater critic" with his negative comments about theater owing to his idealistic views about "the truth." Then came Aristotle who used a different viewpoint from that of Plato, saying that there is "truth" in theater. However, hostile criticism on theater came back in the Middle Ages, championed by Tertulian before Aristotelian theory was revived by the neo-classicists such as Scaliger and Castelvetro. Theater theory and criticism discourse was then made more alive by the romanticists who disagreed with the neo-classicists' rigid rules on theater. As the influence of science became dominant in the theater world, naturalism and realism emerged and became the mainstream of theater theory and criticism until well into the twentieth century.

  18. The necessity of dialectics according to Plato and Adorno

    DEFF Research Database (Denmark)

    Olsen, Anne-Marie Eggert

    2009-01-01

    The paper deals with the notion of philosophy as, on the one hand, an academic or scientific discipline and, on the other, something perhaps superior to the disciplines and in any case dealing with what is not a 'disciplinary' matter. Through an interpretation of Plato's concept of dialectics and...... and Adorno's understanding of philosophy as expression (Ausdruck) it is proposed that this two-fold nature of philosophy is what makes dialectics necessary....

  19. Optical and dark characterization of the PLATO CCD at ESA

    Science.gov (United States)

    Verhoeve, Peter; Prod'homme, Thibaut; Oosterbroek, Tim; Duvet, Ludovic; Beaufort, Thierry; Blommaert, Sander; Butler, Bart; Heijnen, Jerko; Lemmel, Frederic; van der Luijt, Cornelis; Smit, Hans; Visser, Ivo

    2016-07-01

    PLATO - PLAnetary Transits and Oscillations of stars - is the third medium-class mission (M3) to be selected in the European Space Agency (ESA) Science and Robotic Exploration Cosmic Vision programme. It is due for launch in 2025 with the main objective to find and study terrestrial planets in the habitable zone around solar-like stars. The payload consists of >20 cameras; with each camera comprising 4 Charge-Coupled Devices (CCDs), a large number of flight model devices procured by ESA shall ultimately be integrated on the spacecraft. The CCD270 - specially designed and manufactured by e2v for the PLATO mission - is a large format (8 cm x 8 cm) back-illuminated device operating at 4 MHz pixel rate and coming in two variants: full frame and frame transfer. In order to de-risk the PLATO CCD procurement and aid the mission definition process, ESA's Payload Technology Validation section is currently validating the PLATO CCD270. This validation consists in demonstrating that the device achieves its specified electrooptical performance in the relevant environment: operated at 4 MHz, at cold and before and after proton irradiation. As part of this validation, CCD270 devices have been characterized in the dark as well as optically with respect to performance parameters directly relevant for the photometric application of the CCDs. Dark tests comprise the measurement of gain sensitivity to bias voltages, charge injection tests, and measurement of hot and variable pixels after irradiation. In addition, the results of measurements of Quantum Efficiency for a range of angles of incidence, intra- pixel response (non-)uniformity, and response to spot illumination, before and after proton irradiation. In particular, the effect of radiation induced degradation of the charge transfer efficiency on the measured charge in a star-like spot has been studied as a function of signal level and of position on the pixel grid, Also, the effect of various levels of background light on the

  20. The Philosopher's Arete or theStructure of Plato's Parmenides

    Directory of Open Access Journals (Sweden)

    Raúl Gutierrez

    1998-12-01

    Full Text Available The controversy conceming the unity of Plato's Parmenides and the meaning of its first part is stillongoing. The A. proposes a solution, pointing out its structural coincidence with the Republic's simile of the line. This leads him to confine young Socrates in the segment that corresponds to óuivoux and old Parmenides in the vór¡olc; segment. As the one who "possesses insight" of truth based on his apprehension of the One-Good. Parmenides is the actual representative of the philosopher's arete.

  1. Tibial plato leveling osteotomy / Osteotomia de nivelamento do plato da tíbia

    Directory of Open Access Journals (Sweden)

    Julia Maria Matera

    2008-08-01

    Full Text Available The tibial plateau leveling osteotomy (TPLO is a relatively new and innovative surgical treatment for the cranial cruciate ligament rupture in the canine species. The real intent of the procedure is to provide functional stability to the stifle joint by eliminating or neutralizing the cranial tibial thrust during weight bearing instead to restore the cranial cruciate ligament function. The proposal of this study is to report a review of the TPLO procedure, emphasizing procedure, surgical technique, post operative care and complications. The TPLO procedure consists in a radial osteotomy in the tibial plato and rotation of the caudal plateau in order to obtain a desired angle. After the leveling of the tibial plateau, a bone plate and screws are used to stabilize the osteotomy until bone is healed up. The complications that have been associated with the procedure include tibial tuberosity fracture and patellar tendon tendinosis. This procedure has become increasingly more popular for surgical treatment of cranial cruciate ligament injuries in large breed dog. The long term clinical results have not been completely elucidated yet. It has been showed that this technique doesn’t halt the degenerative joint disease.A osteotomia do platô da tíbia (TPLO é um tratamento relativamente novo e inovador para a ruptura do ligamento cruzado cranial (RLCC na espécie canina. Ao invés de restaurar a função do ligamento, o procedimento promove estabilidade funcional para a articulação do joelho, por eliminar ou neutralizar a força tibial cranial durante a sustentação de peso. A proposta do presente estudo é revisar a técnica de TPLO, enfatizando o procedimento, técnica cirúrgica, cuidados pós-operatórios e complicações. A técnica da TPLO consiste na realização de uma osteotomia circular do platô da tíbia com rotação de sua porção caudal até a obtenção do ângulo desejado. Após o nivelamento do platô da tíbia, placa e parafusos

  2. Reversing Plato’s Anti-Democratism: Castoriadis’ “Quirky” Plato

    Directory of Open Access Journals (Sweden)

    Hamblet, Wendy C.

    2008-12-01

    Full Text Available This paper considers the conflicting "loves" of Cornelius Castoriadis--his love for the ancients, and especially Plato, and for the common person of the demos. A detailed study of Castoriadis' analysis of Plato's Statesman exposes that Castoriadis attempts to resolve the paradox by rereading Plato as a radical democrat. I argue that this unorthodox reading is at best "quirky, " (a charge Castoriadis levels at Plato at worst a groundless sophism. However, I conjecture that Castoriadis' reading may not constitute a serious attempt to describe a Platonic politics, so much as a prescriptive reading of what otherwise might have been, given certain strands of political generosity evident elsewhere in Plato's corpus.

  3. Radiation, Thermal Gradient and Weight: a threefold dilemma for PLATO

    Science.gov (United States)

    Magrin, Demetrio; Ragazzoni, Roberto; Bruno, Giordano; Piazza, Daniele; Borsa, Francesco; Ghigo, Mauro; Mogulsky, Valery; Bergomi, Maria; Biondi, Federico; Chinellato, Simonetta; Dima, Marco; Farinato, Jacopo; Greggio, Davide; Gullieuszik, Marco; Marafatto, Luca; Viotto, Valentina; Munari, Matteo; Pagano, Isabella; Sicilia, Daniela; Basso, Stefano; Spiga, Daniele; Bandy, Timothy; Brändli, Mathias; Benz, Willy; De Roche, Thierry; Rieder, Martin; Brandeker, Alexis; Klebor, Maximilian; Schweitzer, Mario; Wieser, Matthias; Erikson, Anders; Rauer, Heike

    2016-07-01

    The project PLAnetary Transits and Oscillations of stars (PLATO) is one of the selected medium class (M class) missions in the framework of the ESA Cosmic Vision 2015-2025 program. The mean scientific goal of PLATO is the discovery and study of extrasolar planetary systems by means of planetary transits detection. The opto mechanical subsystem of the payload is made of 32 normal telescope optical units (N-TOUs) and 2 fast telescope optical units (FTOUs). The optical configuration of each TOU is an all refractive design based on six properly optimized lenses. In the current baseline, in front of each TOU a Suprasil window is foreseen. The main purposes of the entrance window are to shield the following lenses from possible damaging high energy radiation and to mitigate the thermal gradient that the first optical element will experience during the launch from ground to space environment. In contrast, the presence of the window increases the overall mass by a non-negligible quantity. We describe here the radiation and thermal analysis and their impact on the quality and risks assessment, summarizing the trade-off process with pro and cons on having or dropping the entrance window in the optical train.

  4. Manufacturing and alignment tolerance analysis through Montecarlo approach for PLATO

    Science.gov (United States)

    Magrin, Demetrio; Ragazzoni, Roberto; Bergomi, Maria; Biondi, Federico; Chinellato, Simonetta; Dima, Marco; Farinato, Jacopo; Greggio, Davide; Gullieuszik, Marco; Marafatto, Luca; Viotto, Valentina; Munari, Matteo; Pagano, Isabella; Sicilia, Daniela; Basso, Stefano; Borsa, Francesco; Ghigo, Mauro; Spiga, Daniele; Bandy, Timothy; Brändli, Mathias; Benz, Willy; Bruno, Giordano; De Roche, Thierry; Piazza, Daniele; Rieder, Martin; Brandeker, Alexis; Klebor, Maximilian; Mogulsky, Valery; Schweitzer, Mario; Wieser, Matthias; Erikson, Anders; Rauer, Heike

    2016-07-01

    The project PLAnetary Transits and Oscillations of stars (PLATO) is one of the selected medium class (M class) missions in the framework of the ESA Cosmic Vision 2015-2025 program. The main scientific goal of PLATO is the discovery and study of extrasolar planetary systems by means of planetary transits detection. According to the current baseline, the scientific payload consists of 34 all refractive telescopes having small aperture (120mm) and wide field of view (diameter greater than 37 degrees) observing over 0.5-1 micron wavelength band. The telescopes are mounted on a common optical bench and are divided in four families of eight telescopes with an overlapping line-of-sight in order to maximize the science return. Remaining two telescopes will be dedicated to support on-board star-tracking system and will be specialized on two different photometric bands for science purposes. The performance requirement, adopted as merit function during the analysis, is specified as 90% enclosed energy contained in a square having size 2 pixels over the whole field of view with a depth of focus of +/-20 micron. Given the complexity of the system, we have followed a Montecarlo analysis approach for manufacturing and alignment tolerances. We will describe here the tolerance method and the preliminary results, speculating on the assumed risks and expected performances.

  5. Crystallization and preliminary X-ray diffraction analysis of two N-terminal fragments of the DNA-cleavage domain of topoisomerase IV from Staphylococcus aureus

    Energy Technology Data Exchange (ETDEWEB)

    Carr, Stephen B., E-mail: bmbsbc@bmb.leeds.ac.uk [Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT (United Kingdom); Makris, George [Omega Mediation Hellas Ltd, Clinical and Pharma Consulting, 11525 N. Psychiko, Athens (Greece); Phillips, Simon E. V.; Thomas, Christopher D. [Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT (United Kingdom)

    2006-11-01

    The crystallization and data collection of topoisomerase IV from S. aureus is described. Phasing by molecular replacement proved difficult owing to the presence of translational NCS and strategies used to overcome this are discussed. DNA topoisomerase IV removes undesirable topological features from DNA molecules in order to help maintain chromosome stability. Two constructs of 56 and 59 kDa spanning the DNA-cleavage domain of the A subunit of topoisomerase IV from Staphylococcus aureus (termed GrlA56 and GrlA59) have been crystallized. Crystals were grown at 291 K using the sitting-drop vapour-diffusion technique with PEG 3350 as a precipitant. Preliminary X-ray analysis revealed that GrlA56 crystals belong to space group P2{sub 1}, diffract to a resolution of 2.9 Å and possess unit-cell parameters a = 83.6, b = 171.5, c = 87.8 Å, β = 90.1°, while crystals of GrlA59 belong to space group P2{sub 1}2{sub 1}2, with unit-cell parameters a = 41.5, b = 171.89, c = 87.9 Å. These crystals diffract to a resolution of 2.8 Å. This is the first report of the crystallization and preliminary X-ray analysis of the DNA-cleavage domain of a topoisomerase IV from a Gram-positive organism.

  6. Crystallization and preliminary X-ray diffraction analysis of two N-terminal fragments of the DNA-cleavage domain of topoisomerase IV from Staphylococcus aureus.

    Science.gov (United States)

    Carr, Stephen B; Makris, George; Phillips, Simon E V; Thomas, Christopher D

    2006-11-01

    DNA topoisomerase IV removes undesirable topological features from DNA molecules in order to help maintain chromosome stability. Two constructs of 56 and 59 kDa spanning the DNA-cleavage domain of the A subunit of topoisomerase IV from Staphylococcus aureus (termed GrlA56 and GrlA59) have been crystallized. Crystals were grown at 291 K using the sitting-drop vapour-diffusion technique with PEG 3350 as a precipitant. Preliminary X-ray analysis revealed that GrlA56 crystals belong to space group P2(1), diffract to a resolution of 2.9 A and possess unit-cell parameters a = 83.6, b = 171.5, c = 87.8 A, beta = 90.1 degrees, while crystals of GrlA59 belong to space group P2(1)2(1)2, with unit-cell parameters a = 41.5, b = 171.89, c = 87.9 A. These crystals diffract to a resolution of 2.8 A. This is the first report of the crystallization and preliminary X-ray analysis of the DNA-cleavage domain of a topoisomerase IV from a Gram-positive organism.

  7. Love as an Object of Initiation in Plato's Philosophy

    Directory of Open Access Journals (Sweden)

    Euaggelia Maraggianou

    2007-07-01

    Full Text Available Initiation ( muvhsh was the first stage of the ancient mysteries celebrating Demeter, the earth-goddess, and her daughter Kore, soon identified with Persephone or Persephasa, a pre-Greek deity of the underworld. Next came the stage of contemplation ( ejpopteiva , at which worshippers were shown a vision of the goddess of Hades. This led them to identify themselves with her, thus reaching the highest form of happiness. The Eleusinian Mysteries were inseparably linked to the Orphic doctrine, which in its turn influenced the thought of Plato. Plato sees love as an object of initiation and as one of the greatest mysteries of human existence. Plato’s dialogues, Phaedrus and Symposium, contain expressions borrowed directly from the vocabulary of the Mysteries. Although neither Socrates in Phaedrus nor Diotima in Symposium make any explicit reference to the mystic ceremonies, it is certain that both allude to them in expounding the mysteries of spiritual life. The latter has to start at the stage of physical love in order to end up in the contemplation of Ideas. The mystery into which Socrates is initiated by Diotima is the following: there is a mystic stairway leading from the earth to the sky, from man to God. It is made visible by Love, and its steps are represented by different kinds of beauty. The ascent is a gradual one, with a long stop at each of the stages. In this way Love, disciplined by philosophy and spiritualised by increasing de-personalisation, ends up in the Intellectual, conceiving the latter with an intuitive insight. By this spiritual process, one is purified, led to the road of salvation and enabled to participate in the Divine.

  8. PLATO as it is : A legacy mission for Galactic archaeology

    Science.gov (United States)

    Miglio, A.; Chiappini, C.; Mosser, B.; Davies, G. R.; Freeman, K.; Girardi, L.; Jofré, P.; Kawata, D.; Rendle, B. M.; Valentini, M.; Casagrande, L.; Chaplin, W. J.; Gilmore, G.; Hawkins, K.; Holl, B.; Appourchaux, T.; Belkacem, K.; Bossini, D.; Brogaard, K.; Goupil, M.-J.; Montalbán, J.; Noels, A.; Anders, F.; Rodrigues, T.; Piotto, G.; Pollacco, D.; Rauer, H.; Prieto, C. Allende; Avelino, P. P.; Babusiaux, C.; Barban, C.; Barbuy, B.; Basu, S.; Baudin, F.; Benomar, O.; Bienaymé, O.; Binney, J.; Bland-Hawthorn, J.; Bressan, A.; Cacciari, C.; Campante, T. L.; Cassisi, S.; Christensen-Dalsgaard, J.; Combes, F.; Creevey, O.; Cunha, M. S.; Jong, R. S.; Laverny, P.; Degl'Innocenti, S.; Deheuvels, S.; Depagne, É.; Ridder, J.; Matteo, P. Di; Mauro, M. P. Di; Dupret, M.-A.; Eggenberger, P.; Elsworth, Y.; Famaey, B.; Feltzing, S.; García, R. A.; Gerhard, O.; Gibson, B. K.; Gizon, L.; Haywood, M.; Handberg, R.; Heiter, U.; Hekker, S.; Huber, D.; Ibata, R.; Katz, D.; Kawaler, S. D.; Kjeldsen, H.; Kurtz, D. W.; Lagarde, N.; Lebreton, Y.; Lund, M. N.; Majewski, S. R.; Marigo, P.; Martig, M.; Mathur, S.; Minchev, I.; Morel, T.; Ortolani, S.; Pinsonneault, M. H.; Plez, B.; Moroni, P. G. Prada; Pricopi, D.; Recio-Blanco, A.; Reylé, C.; Robin, A.; Roxburgh, I. W.; Salaris, M.; Santiago, B. X.; Schiavon, R.; Serenelli, A.; Sharma, S.; Aguirre, V. Silva; Soubiran, C.; Steinmetz, M.; Stello, D.; Strassmeier, K. G.; Ventura, P.; Ventura, R.; Walton, N. A.; Worley, C. C.

    2017-07-01

    Deciphering the assembly history of the Milky Way is a formidable task, which becomes possible only if one can produce high-resolution chrono-chemo-kinematical maps of the Galaxy. Data from large-scale astrometric and spectroscopic surveys will soon provide us with a well-defined view of the current chemo-kinematical structure of the Milky Way, but will only enable a blurred view on the temporal sequence that led to the present-day Galaxy. As demonstrated by the (ongoing) exploitation of data from the pioneering photometric missions CoRoT, Kepler, and K2, asteroseismology provides the way forward: solar-like oscillating giants are excellent evolutionary clocks thanks to the availability of seismic constraints on their mass and to the tight age-initial-mass relation they adhere to. In this paper we identify five key outstanding questions relating to the formation and evolution of the Milky Way that will need precise and accurate ages for large samples of stars to be addressed, and we identify the requirements in terms of number of targets and the precision on the stellar properties that are needed to tackle such questions. By quantifying the asteroseismic yields expected from PLATO for red-giant stars, we demonstrate that these requirements are within the capabilities of the current instrument design, provided that observations are sufficiently long to identify the evolutionary state and allow robust and precise determination of acoustic-mode frequencies. This will allow us to harvest data of sufficient quality to reach a 10% precision in age. This is a fundamental pre-requisite to then reach the more ambitious goal of a similar level of accuracy, which will only be possible if we have to hand a careful appraisal of systematic uncertainties on age deriving from our limited understanding of stellar physics, a goal which conveniently falls within the main aims of PLATO's core science.

  9. Angiographic outcomes in the PLATO Trial (Platelet Inhibition and Patient Outcomes)

    National Research Council Canada - National Science Library

    Kunadian, Vijay; James, Stefan K; Wojdyla, Daniel M; Zorkun, Cafer; Wu, Jinhui; Storey, Robert F; Steg, Ph Gabriel; Katus, Hugo; Emanuelsson, Hakan; Horrow, Jay; Maya, Juan; Wallentin, Lars; Harrington, Robert A; Gibson, C Michael

    2013-01-01

    The PLATO (Platelet Inhibition and Patient Outcomes) angiographic substudy sought to compare the efficacy of ticagrelor versus clopidogrel with respect to angiographic outcomes before and after PCI in the setting of acute coronary syndrome...

  10. The Legacies of Literacy: From Plato to Freire through Harvey Graff.

    Science.gov (United States)

    Gee, James Paul

    1989-01-01

    Reviews "The Legacies of Literacy: Continuities and Contradictions in Western Culture and Society" (Harvey G. Graff). Discusses the historical role of literacy education as a tool for liberation, emphasizing the viewpoints of Plato and Freire. (FMW)

  11. Genesis 2–3 and Alcibiades's speech in Plato's Symposium : A ...

    African Journals Online (AJOL)

    Genesis 2–3 and Alcibiades's speech in Plato's Symposium : A cultural critical reading. ... interpretation can arise from the analysis of Alcibiades's speech compared to M- and LXX-Genesis ... EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT

  12. Prospects for detecting decreasing exoplanet frequency with main sequence age using PLATO

    CERN Document Server

    Veras, Dimitri; Mustill, Alexander J; Pollacco, Don

    2015-01-01

    The space mission PLATO will usher in a new era of exoplanetary science by expanding our current inventory of transiting systems and constraining host star ages, which are currently highly uncertain. This capability might allow PLATO to detect changes in planetary system architecture with time, particularly because planetary scattering due to Lagrange instability may be triggered long after the system was formed. Here, we utilize previously published instability timescale prescriptions to determine PLATO's capability to detect a trend of decreasing planet frequency with age for systems with equal-mass planets. For two-planet systems, our results demonstrate that PLATO may detect a trend for planet masses which are at least as massive as super-Earths. For systems with three or more planets, we link their initial compactness to potentially detectable frequency trends in order to aid future investigations when these populations will be better characterized.

  13. Plato's Charmides as a Political Act: Apologetics and the Promotion of Ideology

    National Research Council Canada - National Science Library

    Danzig, Gabriel

    2013-01-01

      By showing that Critias and Socrates understood the same matters differently, Plato was able to treat seriously ideas that came to be associated with the Thirty and with Socrates while shielding himself from criticism...

  14. Platerm: la banque de terminologie du systeme Platon (PLATERM: The Terminology Bank of the PLATO System).

    Science.gov (United States)

    Schwab, Wallace; St-Denis, Richard

    1980-01-01

    Describes the elements and functioning of the terminology bank of the PLATO (Programmed Loqic for Automated Teaching Operation) system. Discusses contemporary terminology and lexicography notions on which the bank is based and outlines the tasks performed through PLATERM. (MES)

  15. Platerm: la banque de terminologie du systeme Platon (PLATERM: The Terminology Bank of the PLATO System).

    Science.gov (United States)

    Schwab, Wallace; St-Denis, Richard

    1980-01-01

    Describes the elements and functioning of the terminology bank of the PLATO (Programmed Loqic for Automated Teaching Operation) system. Discusses contemporary terminology and lexicography notions on which the bank is based and outlines the tasks performed through PLATERM. (MES)

  16. Primary structure of human alpha 2-macroglobulin. IV. Primary structure of two large CNBr fragments, located in the COOH-terminal part and accounting for 337 residues

    DEFF Research Database (Denmark)

    Kristensen, Torsten; Wierzbicki, D M; Sottrup-Jensen, Lars

    1984-01-01

    The amino acid sequences have been determined for two CNBr fragments of human alpha 2-macroglobulin which, due to the presence of an uncleaved Hse-Thr bond, form an Mr = 40,000 fragment. These fragments are located in the COOH-terminal part of alpha 2-macroglobulin (CB21, residues 955-1185 and CB......, residues 1186-1291). CB21 contains one glucosamine-based carbohydrate group attached to Asn-14 and one internal disulfide bridge (Cys-102 bound to Cys-150). CB21 and CB22 account for 337 of the 1451 residues of the subunit of alpha 2-macroglobulin....

  17. Evaluation of Columbia, USMARC-Composite, Suffolk, and Texel rams as terminal sires in an extensive rangeland production system: IV. Postfabrication carcass component weights.

    Science.gov (United States)

    Mousel, M R; Notter, D R; Leeds, T D; Zerby, H N; Moeller, S J; Lewis, G S

    2013-05-01

    Postfabrication carcass component weights of 517 crossbred wether lambs were analyzed to evaluate 4 terminal-sire breeds. Wethers were produced over 3 yr from single-sire matings of 22 Columbia, 22 USMARC-Composite (Composite), 21 Suffolk, and 17 Texel rams to adult Rambouillet ewes. Lambs were reared to weaning in an extensive western rangeland production system and finished in a feedlot on a high-energy finishing diet. When wethers reached a mean BW of 54.4, 61.2, or 68.0 kg, they were transported to The Ohio State University abattoir for harvest. After refrigeration for approximately 24 h, chilled carcass weight (CCW) was measured, carcasses were fabricated according to Style A of Institutional Meat Purchase Specifications, and postfabrication weights were recorded. At comparable numbers of days on feed, Suffolk-sired lambs had heavier (P wholesale cut weights) and high-value trimming loss were greatest (P 0.06) flank weight. Data adjusted to comparable CCW reduced the number of significant sire-breed effects and changed sire-breed rankings of carcass component weights, for which sire breeds differed. After adjusting, Suffolk-sired lambs had lighter (P < 0.05) loins than Columbia- and Composite-sired lambs, Composite-sired lambs had heavier (P < 0.05) high-value cuts than Suffolk-sired lambs, and Suffolk- and Columbia-sired lambs had heavier (P < 0.05) necks than Texel-sired lambs. At predicted backfat thickness of 6.6 mm, Composite-sired lambs had a greater (P < 0.05) percentage of high-value cuts than Suffolk-sired lambs before but not after trimming. Producers can use these results to select terminal-sire breeds that will complement their production system and improve lamb value.

  18. The PLATO Dome A site-testing observatory: Power generation and control systems

    Science.gov (United States)

    Lawrence, J. S.; Ashley, M. C. B.; Hengst, S.; Luong-van, D. M.; Storey, J. W. V.; Yang, H.; Zhou, X.; Zhu, Z.

    2009-06-01

    The atmospheric conditions above Dome A, a currently unmanned location at the highest point on the Antarctic plateau, are uniquely suited to astronomy. For certain types of astronomy Dome A is likely to be the best location on the planet, and this has motivated the development of the Plateau Observatory (PLATO). PLATO was deployed to Dome A in early 2008. It houses a suite of purpose-built site-testing instruments designed to quantify the benefits of Dome A site for astronomy, and science instruments designed to take advantage of the observing conditions. The PLATO power generation and control system is designed to provide continuous power and heat, and a high-reliability command and communications platform for these instruments. PLATO has run and collected data throughout the winter 2008 season completely unattended. Here we present a detailed description of the power generation, power control, thermal management, instrument interface, and communications systems for PLATO, and an overview of the system performance for 2008.

  19. Gaia and WEAVE/WxES: Supporting the PLATO Exoplanet Hunter

    Science.gov (United States)

    Walton, N. A.

    2016-10-01

    This paper briefly describes the powerful linkages between the Gaia and PLATO missions and the potential for WEAVE in the study of exoplanet populations, for instance through the proposed WxES survey. Gaia successfully launched in December 2013, and over the course of its nominal five year mission will discover, via their astrometric signatures, upwards of 20 000 massive Jupiter sized long period planets at distances out to several hundred parsecs around all star types. In addition Gaia will discover up to a thousand short period hot Jupiters around M stars. PLATO, to launch in 2024, will through precision photometry, observe in detail some million host stars, and will detect, via the transit technique, planets down to Earth masses. PLATO will observe two fields of over 2 000 square degrees for 2-3 years each. At least one of these will be in the northern hemisphere. WEAVE has the potential to provide detailed chemical characterization of the host stars of the Gaia and PLATO exoplanet systems. This will enable insights into, for instance, metallicity of the host star correlations against both massive exoplanets (perhaps confirming current relationships), and lower mass exoplanets. We note how the rapid exploitation of such a potential WEAVE survey could be achieved, utilizing the WEAVE processing systems being developed at the IoA, Cambridge, coupled with efficient interfaces to both Gaia and PLATO data products, that are also being generated at the IoA.

  20. The role of the poet in Plato's ideal cities of Callipolis and Magnesia

    Directory of Open Access Journals (Sweden)

    Gerard Naddaf

    2008-01-01

    Full Text Available Plato's attitude toward the poets and poetry has always been a flashpoint of debate, controversy and notoriety, but most scholars have failed to see their central role in the ideal cities of the Republic and the Laws, that is, Callipolis and Magnesia. In this paper, I argue that in neither dialogue does Plato "exile" the poets, but, instead, believes they must, like all citizens, exercise the expertise proper to their profession, allowing them the right to become full-fledged participants in the productive class. Moreover, attention to certain details reveals that Plato harnesses both positive and negative factors in poetry to bring his ideal cities closer to a practical realization. The status of the poet and his craft in this context has rarely to my knowledge been addressed.

  1. PLATO - the next-generation AASTINO for robotic site-testing on the Antarctic plateau

    Science.gov (United States)

    Hengst, S.; Lawrence, J.; Luong-van, D.; Everett, J.; Ashley, M. C. B.; Storey, J. W. V.; Hall, S.

    2006-08-01

    A new site-testing facility, PLATO (Plateau Observatory), is under development at UNSW for deployment to remote sites on the Antarctic Plateau including Dome A. The new facility will adopt many of the features of the AASTINO (Automated Astrophysical Site Testing InterNational Observatory) facility at Dome C. PLATO will autonomously control a flexible site testing and observing instrument suite, monitored via the Iridium satellite network. A challenging aspect of PLATO is to maximise the reliability of the power source while minimising fuel consumption. We are building a low pressure, low temperature environmental chamber to simulate operation at the highest altitudes (4,100 m at Dome A). Two types of engines will be tested: a single-cylinder diesel engine and a Stirling engine.

  2. Efficient methods for solving discrete topology design problems in the PLATO-N project

    DEFF Research Database (Denmark)

    Canh, Nam Nguyen; Stolpe, Mathias

    This paper considers the general multiple load structural topology design problems in the framework of the PLATO-N project. The problems involve a large number of discrete design variables and were modeled as a non-convex mixed 0–1 program. For the class of problems considered, a global optimizat......This paper considers the general multiple load structural topology design problems in the framework of the PLATO-N project. The problems involve a large number of discrete design variables and were modeled as a non-convex mixed 0–1 program. For the class of problems considered, a global...

  3. The quest for a poetics of goodness in plato and aristotle

    OpenAIRE

    Dairo Orozco

    2012-01-01

    The paper, which compares Plato and Aristotle’s different approaches towards artistic activity, is divided into three parts. The first part discusses Plato’s Ion on mimesis and technē, as well as the role that poetry plays in the Republic. The second section offers an account of Aristotle’s idea of happiness as the end of action. Thelast section of this study deals with an attempt to reconcile Plato and Aristotle’s attitude towards mimetic art in a treatise by a Neoplatonic renaissance thinke...

  4. A Similar Comparison between the Thought of Plato and Confucius on Social Hierarchy and Elitism

    Institute of Scientific and Technical Information of China (English)

    杨馥遥

    2014-01-01

    The spring-autumn period and warring state period of Chinese thoughts coincide strikingly with the thoughts of the Hel enic Age in the west. Plato and Confucius, the two outstanding seminal thinkers have shaped the philosophy of their respective cultures through some similar means and thoughts which definitely meet at a series of significant points. The highlight of the academic thesis lies in the comparison of the general similarities be-tween Plato and Confucius especial y in terms of social hierarchy and elitism.

  5. The PLATO End-to-End CCD Simulator -- Modelling space-based ultra-high precision CCD photometry for the assessment study of the PLATO Mission

    CERN Document Server

    Zima, W; De Ridder, J; Salmon, S; Catala, C; Kjeldsen, H; Aerts, C

    2010-01-01

    The PLATO satellite mission project is a next generation ESA Cosmic Vision satellite project dedicated to the detection of exo-planets and to asteroseismology of their host-stars using ultra-high precision photometry. The main goal of the PLATO mission is to provide a full statistical analysis of exo-planetary systems around stars that are bright and close enough for detailed follow-up studies. Many aspects concerning the design trade-off of a space-based instrument and its performance can best be tackled through realistic simulations of the expected observations. The complex interplay of various noise sources in the course of the observations made such simulations an indispensable part of the assessment study of the PLATO Payload Consortium. We created an end-to-end CCD simulation software-tool, dubbed PLATOSim, which simulates photometric time-series of CCD images by including realistic models of the CCD and its electronics, the telescope optics, the stellar field, the pointing uncertainty of the satellite ...

  6. ST-elevation acute coronary syndromes in the Platelet Inhibition and Patient Outcomes (PLATO) trial

    DEFF Research Database (Denmark)

    Armstrong, Paul W; Siha, Hany; Fu, Yuling;

    2012-01-01

    Ticagrelor, when compared with clopidogrel, reduced the 12-month risk of vascular death/myocardial infarction and stroke in patients with ST-elevation acute coronary syndromes intended to undergo primary percutaneous coronary intervention in the PLATelet inhibition and patient Outcomes (PLATO) tr...

  7. Democratic Freedom and the Concept of Freedom in Plato and Aristotle

    Directory of Open Access Journals (Sweden)

    Mogens Herman Hansen

    2010-11-01

    Full Text Available Among the several meanings of eleutheria used by Greeks in the classical period, democratic freedom is rejected by both Plato and Aristotle, who do not articulate a theory of political freedom but rather confine eleutheria to a social context.

  8. Freud, Plato and Irigaray: A Morpho-Logic of Teaching and Learning

    Science.gov (United States)

    Peers, Chris

    2012-01-01

    This article discusses two well-known texts that respectively describe learning and teaching, drawn from the work of Freud and Plato. These texts are considered in psychoanalytic terms using a methodology drawn from the philosophy of Luce Irigaray. In particular the article addresses Irigaray's approach to the analysis of speech and utterance as a…

  9. Dialectic of Eros and Myth of the Soul in Plato's Phaedrus

    DEFF Research Database (Denmark)

    Larsen, Jens Kristian

    2010-01-01

    In this paper, I question a widespread reading of a passage in the last part of the Phaedrus dealing with the science of dialectic. According to this reading, the passage announces a new method peculiar to the later Plato aiming at defining natural kinds. I show that the Phaedrus itself does not ...

  10. Cost of Initial Development of PLATO Instruction in Veterinary Medicine. CERL Report X-43.

    Science.gov (United States)

    Grimes, George M.

    An academic program instituting the PLATO system of computer-assisted instruction at the University of Illinois College of Veterinary Medicine is discussed. Procedures involved setting up an organization, establishing an administrative system, studying capabilities of the system, studying factors making a lesson suitable for programming, and…

  11. From Dialogos to Dialogue: The Use of the Term from Plato to the Second Century CE

    Directory of Open Access Journals (Sweden)

    Katarzyna Jazdzewska

    2014-02-01

    Full Text Available In Plato the verb διαλέγεσθαι is far more common than the noun, and both denote question-and-answer discussions; it was only in the Hellenistic period that διάλογος became a genre term, though its other meanings survived.

  12. Two examples of the relation between the contemporary science and Plato

    CERN Document Server

    Antonello, Elio

    2016-01-01

    The philosopher Plato is remembered even today by scientists, and his writings are still inspiring the scientific research. In the present short note (intended essentially for public outreach) two examples are briefly illustrated: 1) the European space project that bears his name, dedicated to the discovery of exoplanets; 2) the discussion about platonism in contemporary physics.

  13. Grades 1-8, Apache Junction Unified School District 43, Apache Junction, Arizona. PLATO Evaluation Series.

    Science.gov (United States)

    Quinn, David W.; Quinn, Nancy W.

    Apache Junction Unified School District, Arizona, has embarked on a 5-year program of instructional improvement using technology. PLATO Elementary reading and mathematics products were installed in the district's elementary and middle schools at the beginning of the 1999-2000 school year. This evaluation studied the use and preliminary student…

  14. Can Prior Knowledge Hurt Text Comprehension? An Answer Borrowed from Plato, Aristotle, and Descartes.

    Science.gov (United States)

    Friedman, Lawrence B.

    Taking a philosophical approach based on what Plato, Aristotle, and Descartes said about knowledge, this paper addresses some of the murkiness in the conceptual space surrounding the issue of whether prior knowledge does or does not facilitate text comprehension. Specifically, the paper first develops a non-exhaustive typology of cases in which…

  15. A Philosophical Investigation of the Role of Teachers: A Synthesis of Plato, Confucius, Buber, and Freire

    Science.gov (United States)

    Shim, Seung Hwan

    2008-01-01

    This study proposes the ideal role of teachers through the examination of Plato, Confucius, Buber, and Freire on the subject. Teachers not only contribute to the development of individuals and societies but also attain self-realization through teaching. As such, the role of teachers is important as a goal as well as a means. To examine such role,…

  16. Genesis 2–3 and Alcibiades's speech in Plato's Symposium: A ...

    African Journals Online (AJOL)

    2015-08-26

    Aug 26, 2015 ... Friedländer 1975:26f; Gauss 1958:111–117) is the last speech in Plato's ... leader (450–404/3 BCE), appears to be in a great state of intoxication .... command (Gn 2:18: 'You are free to eat of all the trees in the garden.

  17. Freud, Plato and Irigaray: A Morpho-Logic of Teaching and Learning

    Science.gov (United States)

    Peers, Chris

    2012-01-01

    This article discusses two well-known texts that respectively describe learning and teaching, drawn from the work of Freud and Plato. These texts are considered in psychoanalytic terms using a methodology drawn from the philosophy of Luce Irigaray. In particular the article addresses Irigaray's approach to the analysis of speech and utterance as a…

  18. From Plato to Erikson: How the War on "Bad Play" Has Impoverished Higher Education

    Science.gov (United States)

    Carnes, Mark C.

    2015-01-01

    For centuries, the titans of educational reform--Plato, Rousseau, Dewey, Piaget, Erikson, Csikszentmihalyi and others--have championed the educational benefits of play. Yet many professors and administrators are boggled by the idea of playing academic games in college. They instantly dismiss faculty initiatives like "Reacting to the…

  19. 29 CFR 4022.63 - Estimated title IV benefit.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false Estimated title IV benefit. 4022.63 Section 4022.63 Labor... PAYABLE IN TERMINATED SINGLE-EMPLOYER PLANS Benefit Reductions in Terminating Plans § 4022.63 Estimated... administrator shall determine each participant's estimated title IV benefit. The estimated title IV...

  20. Plato, Wilde, and Woolf: the poetics of homoerotic "intercourse" in A Room of One's Own.

    Science.gov (United States)

    Vanita, Ruth

    2010-01-01

    This article places Woolf in the context of homoerotic literary ancestry. It suggests that the overall argument in A Room of One's Own owes a debt to Wilde's 1891 pamphlet The Soul of Man under Socialism. It also examines Woolf's controversial meditation on male-female collaboration and intercourse in A Room, and suggests a homoerotic reading of this meditation, drawing on images and ideas of literary transmission and creation from Plato's Symposium.

  1. The philosopher Socrates had exophthalmos (a term coined by Plato) and probably Graves' disease.

    Science.gov (United States)

    Papapetrou, Peter D

    2015-01-01

    According to a previously published theory, Socrates was afflicted with temporal lobe epilepsy since his childhood. Plato, Xenophon, and Aristoxenus described Socrates as having exophthalmos, probably diplopia, and some symptoms compatible with hyperthyroidism. Using these data, we theorize that Socrates had Graves' disease. In order to determine a cause of his temporal lobe epilepsy, we speculate that the philosopher also had autoimmune thyroiditis and Hashimoto encephalopathy during his childhood and his epilepsy may have been a sequel to this hypothesized encephalopathy.

  2. The instrument control unit of the ESA-PLATO 2.0 mission

    Science.gov (United States)

    Focardi, M.; Pezzuto, S.; Cosentino, R.; Giusi, G.; Pancrazzi, M.; Noce, V.; Ottensamer, R.; Steller, M.; Di Giorgio, A. M.; Pace, E.; Plasson, P.; Peter, G.; Pagano, I.

    2016-07-01

    PLATO 2.0 has been selected by ESA as the third medium-class Mission (M3) of the Cosmic Vision Program. Its Payload is conceived for the discovery of new transiting exoplanets on the disk of their parent stars and for the study of planetary system formation and evolution as well as to answer fundamental questions concerning the existence of other planetary systems like our own, including the presence of potentially habitable new worlds. The PLATO Payload design is based on the adoption of four sets of short focal length telescopes having a large field of view in order to exploit a large sky coverage and to reach, at the same time, the needed photometry accuracy and signalto- noise ratio (S/N) within a few tens of seconds of exposure time. The large amount of data produced by the telescope is collected and processed by means of the Payload's Data Processing System (DPS) composed by many processing electronics units. This paper gives an overview of the PLATO 2.0 DPS, mainly focusing on the architecture and processing capabilities of its Instrument Control Unit (ICU), the electronic subsystem acting as the main interface between the Payload (P/L) and the Spacecraft (S/C).

  3. Termination Documentation

    Science.gov (United States)

    Duncan, Mike; Hill, Jillian

    2014-01-01

    In this study, we examined 11 workplaces to determine how they handle termination documentation, an empirically unexplored area in technical communication and rhetoric. We found that the use of termination documentation is context dependent while following a basic pattern of infraction, investigation, intervention, and termination. Furthermore,…

  4. Echoes in Plato's cave : ontology of sound objects in computer music and analysis

    OpenAIRE

    Marsden, Alan

    2014-01-01

    The sonic aspects of Plato's analogy of the cave is taken as a starting point for thought experiments to investigate the objective nature of sound, and the idea of quasi-Platonic forms in music. Sounds are found to be objects in a way that sights or appearances are not, and it is only in the presence of technology that they become artificial. When recognition, control and communication about sound come into play, abstract concepts emerge, but there is no reason to give these the priority stat...

  5. Ontological Questions in Schelling’s Late Philosophy: Plato and Aristotle

    Directory of Open Access Journals (Sweden)

    Jean-François Courtine

    2010-09-01

    Full Text Available The purpose of the article is to understand the reasons and procedures employed by F. W. Schelling in his Plato and Aristotle re-appropriation, and to extract the authentically ontological thematic of it. It makes a path through the Schelling’s late writings and letters, to construct a complete view about the relation between this appropriation and the possibility of the constitution of a positive philosophy, as a particular science, in opposition to a negative philosophy, understood as metaphysics.

  6. Numbers Rule The Vexing Mathematics of Democracy, from Plato to the Present

    CERN Document Server

    Szpiro, George G

    2010-01-01

    Since the very birth of democracy in ancient Greece, the simple act of voting has given rise to mathematical paradoxes that have puzzled some of the greatest philosophers, statesmen, and mathematicians. Numbers Rule traces the epic quest by these thinkers to create a more perfect democracy and adapt to the ever-changing demands that each new generation places on our democratic institutions. In a sweeping narrative that combines history, biography, and mathematics, George Szpiro details the fascinating lives and big ideas of great minds such as Plato, Pliny the Younger, Ramon Llull, Pierre Simo

  7. Asteroids IV

    Science.gov (United States)

    Michel, Patrick; DeMeo, Francesca E.; Bottke, William F.

    . Asteroids, like planets, are driven by a great variety of both dynamical and physical mechanisms. In fact, images sent back by space missions show a collection of small worlds whose characteristics seem designed to overthrow our preconceived notions. Given their wide range of sizes and surface compositions, it is clear that many formed in very different places and at different times within the solar nebula. These characteristics make them an exciting challenge for researchers who crave complex problems. The return of samples from these bodies may ultimately be needed to provide us with solutions. In the book Asteroids IV, the editors and authors have taken major strides in the long journey toward a much deeper understanding of our fascinating planetary ancestors. This book reviews major advances in 43 chapters that have been written and reviewed by a team of more than 200 international authorities in asteroids. It is aimed to be as comprehensive as possible while also remaining accessible to students and researchers who are interested in learning about these small but nonetheless important worlds. We hope this volume will serve as a leading reference on the topic of asteroids for the decade to come. We are deeply indebted to the many authors and referees for their tremendous efforts in helping us create Asteroids IV. We also thank the members of the Asteroids IV scientific organizing committee for helping us shape the structure and content of the book. The conference associated with the book, "Asteroids Comets Meteors 2014" held June 30-July 4, 2014, in Helsinki, Finland, did an outstanding job of demonstrating how much progress we have made in the field over the last decade. We are extremely grateful to our host Karri Muinonnen and his team. The editors are also grateful to the Asteroids IV production staff, namely Renée Dotson and her colleagues at the Lunar and Planetary Institute, for their efforts, their invaluable assistance, and their enthusiasm; they made life as

  8. Philosophy and Mathematics in the Teaching of Plato: the Development of Idea and Modernity

    Directory of Open Access Journals (Sweden)

    Mikhailova N. V.

    2014-01-01

    Full Text Available It is well known that the largest philosophers differently explain the origin of mathematics. This question was investigated in antiquity, a substantial and decisive role in this respect was played by the Platonic doctrine. Therefore, discussing this issue the problem of interaction of philosophy and mathematics in the teachings of Plato should be taken into consideration. Many mathematicians believe that abstract mathematical objects belong in a certain sense to the world of ideas and that consistency of objects and theories really describes mathematical reality, as Plato quite clearly expressed his views on math, according to which mathematical concepts objectively exist as distinct entities between the world of ideas and the world of material things. In the context of foundations of mathematics, so called “Gödel’s Platonism” is of particular interest. It is shown in the article how Platonic objectification of mathematical concepts contributes to the development of modern mathematics by revealing philosophical understanding of the nature of abstraction. To substantiate his point of view, the author draws the works of contemporary experts in the field of philosophy of mathematics.

  9. The PLATO Simulator: Modelling of High-Precision High-Cadence Space-Based Imaging

    CERN Document Server

    Marcos-Arenal, P; De Ridder, J; Aerts, C; Huygen, R; Samadi, R; Green, J; Piotto, G; Salmon, S; Catala, C; Rauer, H

    2014-01-01

    Many aspects of the design trade-off of a space-based instrument and its performance can best be tackled through simulations of the expected observations. The complex interplay of various noise sources in the course of the observations make such simulations an indispensable part of the assessment and design study of any space-based mission. We present a formalism to model and simulate photometric time series of CCD images by including models of the CCD and its electronics, the telescope optics, the stellar field, the jitter movements of the spacecraft, and all important natural noise sources. This formalism has been implemented in a versatile end-to-end simulation software tool, called PLATO Simulator, specifically designed for the PLATO space mission to be operated from L2, but easily adaptable to similar types of missions. We provide a detailed description of several noise sources and discuss their properties, in connection with the optical design, the allowable level of jitter, the quantum efficiency of th...

  10. Dialectic and Dialogue in Plato: Refuting the Model of Socrates-as-Teacher in the Pursuit of Authentic "Paideia"

    Science.gov (United States)

    Magrini, James Michael

    2014-01-01

    Incorporating Gadamer and other thinkers from the continental tradition, this essay is a close and detailed hermeneutic, phenomenological, and ontological study of the dialectic practice of Plato's Socrates--it radicalizes and refutes the Socrates-as-teacher model that educators from scholar academic ideology embrace.

  11. Three Aspects of PLATO Use at Chanute AFB: CBE Production Techniques, Computer-Aided Management, Formative Development of CBE Lessons.

    Science.gov (United States)

    Klecka, Joseph A.

    This report describes various aspects of lesson production and use of the PLATO system at Chanute Air Force Base. The first chapter considers four major factors influencing lesson production: (1) implementation of the "lean approach," (2) the Instructional Systems Development (ISD) role in lesson production, (3) the transfer of…

  12. An Evaluation of the Teaching Effectiveness of PLATO in a First Level Biology Course. CERL Report X-32.

    Science.gov (United States)

    Arsenty, Richard P.; Kieffer, George H.

    This paper describes a study of the teaching effectiveness of computer-assisted instruction using the PLATO system at the University of Illinois in a first level biology course. College enrollment, class rank, final grade, and time study data of the control and experimental groups were obtained from master rosters. A questionnaire administered to…

  13. The Education of the Third Class in "The Republic": Plato and the "Locus Classicus" of Formative Justice

    Science.gov (United States)

    Mintz, Avi I.

    2016-01-01

    Background/Context: In one of the classics of educational philosophy, a key issue is remains unsettled. In Plato's "Republic," Socrates makes a case for the importance of a comprehensive education. Socrates is unclear, however, about whether the producer class is eligible for this comprehensive education. Purpose/Objective: Previous…

  14. Dialectic and Dialogue in Plato: Refuting the Model of Socrates-as-Teacher in the Pursuit of Authentic "Paideia"

    Science.gov (United States)

    Magrini, James Michael

    2014-01-01

    Incorporating Gadamer and other thinkers from the continental tradition, this essay is a close and detailed hermeneutic, phenomenological, and ontological study of the dialectic practice of Plato's Socrates--it radicalizes and refutes the Socrates-as-teacher model that educators from scholar academic ideology embrace.

  15. Retrospective study on prognostic importance of serum procalcitonin and amino - terminal pro - brain natriuretic peptide levels as compared to Acute Physiology and Chronic Health Evaluation IV Score on Intensive Care Unit admission, in a mixed Intensive Care Unit population

    Directory of Open Access Journals (Sweden)

    Chitra Mehta

    2016-01-01

    Full Text Available Background: Timely decision making in Intensive Care Unit (ICU is very essential to improve the outcome of critically sick patients. Conventional scores like Acute Physiology and Chronic Health Evaluation (APACHE IV are quite cumbersome with calculations and take minimum 24 hours. Procalcitonin has shown to have prognostic value in ICU/Emergency department (ED in disease states like pneumonia, sepsis etc. NTproBNP has demonstrated excellent diagnostic and prognostic importance in cardiac diseases. It has also been found elevated in non-cardiac diseases. We chose to study the prognostic utility of these markers on ICU admission. Settings and Design: Retrospective observational study. Materials and Methods: A Retrospective analysis of 100 eligible patients was done who had undergone PCT and NTproBNP measurements on ICU admission. Their correlations with all cause mortality, length of hospital stay, need for ventilator support, need for vasopressors were performed. Results: Among 100 randomly selected ICU patients, 28 were non-survivors. NTproBNP values on admission significantly correlated with all cause mortality (P = 0.036, AUC = 0.643 and morbidity (P = 0.000, AUC = 0.763, comparable to that of APACHE-IV score. PCT values on admission did not show significant association with mortality, but correlated well with morbidity and prolonged hospital length of stay (AUC = 0.616, P = 0.045. Conclusion: The current study demonstrated a good predictive value of NTproBNP, in terms of mortality and morbidity comparable to that of APACHE-IV score. Procalcitonin, however, was found to have doubtful prognostic importance. These findings need to be confirmed in a prospective larger study.

  16. The Theory of Argumentation within Language and its relation to Plato, Saussure and Benveniste

    Directory of Open Access Journals (Sweden)

    Cristiane Dall'Cortivo-Lebler

    2014-12-01

    Full Text Available The Theory of Argumentation within Language, developed by Oswald Ducrot, Jean-Claude Anscombre and Marion Carel, has experienced along its development different phases and forms, constantly seeking to align to what its main developer, Oswald Ducrot, called external hypotheses and internal hypotheses. This paper discusses the presence of Linguistic Theories and Philosophy in Ducrot’s work regarding concepts of Plato, Ferdinand de Saussure and Émile Benveniste, which constitute its external assumptions. The presence of these concepts culminated in the creation of different concepts that comprise the Linguistic Semantics, and gave it a specific point of view about language that emphasizes the internal relationships among language components and understands that speech is the result of a linguistic activity where an “I” speaks to a “you”.

  17. Efficient methods for solving discrete topology design problems in the PLATO-N project

    DEFF Research Database (Denmark)

    Canh, Nam Nguyen; Stolpe, Mathias

    This paper considers the general multiple load structural topology design problems in the framework of the PLATO-N project. The problems involve a large number of discrete design variables and were modeled as a non-convex mixed 0–1 program. For the class of problems considered, a global...... optimization method based on the branch-and-cut concept was developed and implemented. In the method a large number of continuous relaxations were solved. We also present an algorithm for generating cuts to strengthen the quality of the relaxations. Several heuristics were also investigated to obtain efficient...... algorithms. The branch and cut method is used to solve benchmark examples which can be used to validate other methods and heuristics....

  18. Banishing the Poet: The Pedagogical Function of Mythology in the Dialogues of Plato

    Directory of Open Access Journals (Sweden)

    Javier Martínez

    2013-06-01

    Full Text Available This text attempts to develop a sound justification for Plato’s pedagogical use of myth in the dialogues. In particular, I seek to resolve a seeming contradiction: why Plato personally made use of myths in spite of his many statements that seem to contradict such a pedagogical approach, especially his edict that poets and myth-makers be banished from his republic for the danger their works pose to the attainment of true philosophical wisdom. An analysis of the centrality of myths to the dialogues is carried out, followed by a discussion of the place of muthos in its Ionian historical context. This establishes the basis for resolving the contradiction through the division of muthos into two distinct modes: the fantastic and the eikastic.

  19. Arete and Gender-Differentiation in Socrates/Plato and Aristotle

    Directory of Open Access Journals (Sweden)

    Thomas Robinson

    1998-12-01

    Full Text Available The article grapples with the question whether Plato believed that, in the matter of arete, the female psyche had a built-in inclination to immorality in a way that the male psyche did not, and was therefore assuch signiticantly different from the male psyche. It is argued that the evidence of the Timaeus ( and, to some lesser degree, of the Laws suggests very strongly that he did, though fortunately the political consequence she drew from this (in the Laws tum out to be positive rather than negative. Aristotle, by contrast,it is argued, while still holding to the lamentable theory of the inferiority of woman, talks of ditl'eringquanta of (one and the same arete in male and female souls, rather than a difference in their very arete.

  20. Platón y el silogismo Plato and the syllogism

    Directory of Open Access Journals (Sweden)

    Manuel Correia Machuca

    2010-03-01

    Full Text Available La cuestión de si Platón pudo ser el autor de una primera noción de deducción silogística (un método que Aristóteles hizo conocido a través de una definición y un progreso teórico en los Analíticos Primeros fue discutida en la antigüedad y, desde entonces, debatida por varios comentaristas. En este artículo, comento dos pasajes de la literatura post-aristotélica, uno atestiguado por Boecio (que se remonta a Alejandro de Afrodisia y el otro presente en Juan Filópono, en su comentario a los Analíticos Primeros. El artículo intenta mostrar que estos pasajes contienen información suficiente para favorecer a Platón como conocedor de la técnica deductiva silogística, aunque no para conferirle el desarrollo de la metodología silogística.The question of whether Plato could be the author of a first concept of syllogistic deduction (a method that Aristotle made known by means of a definition and a theoretical improvement in his Prior Analytics was known in the antiquity and from that time, the question has usually examined by several commentators. In this article, I comment on two passages of post-Aristotelian tradition; one is given by Boethius (which stems from Alexander of Aphrodisias and the other was given by Johannes Philoponus in his commentary on Prior Analytics. The article intends to show that these passages contain information that is sufficient to come to an opinion favoring Plato, although it does not imply that they are sufficient to confer him the syllogistic method.

  1. Simulation results for PLATO: a prototype hybrid X-ray photon counting detector with a low energy threshold for fusion plasma diagnostics

    Science.gov (United States)

    Habib, A.; Menouni, M.; Pangaud, P.; Fenzi, C.; Colledani, G.; Moureau, G.; Escarguel, A.; Morel, C.

    2017-01-01

    PLATO is a prototype hybrid X-ray photon counting detector that has been designed to meet the specifications for plasma diagnostics for the WEST tokamak platform (Tungsten (W) Environment in Steady-state Tokamak) in southern France, with potential perspectives for ITER. PLATO represents a customized solution that fulfills high sensitivity, low dispersion and high photon counting rate. The PLATO prototype matrix is composed of 16 × 18 pixels with a 70 μm pixel pitch. New techniques have been used in analog sensitive blocks to minimize noise coupling through supply rails and substrate, and to suppress threshold dispersion across the matrix. The PLATO ASIC is designed in CMOS 0.13 μm technology and was submitted for a fabrication run in June 2016. The chip is designed to be bump-bonded to a silicon sensor. This paper presents pixel architecture as well as simulation results while highlighting novel solutions.

  2. Terminal structure

    Science.gov (United States)

    Schmidt, Frank; Allais, Arnaud; Mirebeau, Pierre; Ganhungu, Francois; Lallouet, Nicolas

    2009-10-20

    A terminal structure (2) for a superconducting cable (1) is described. It consists of a conductor (2a) and an insulator (2b) that surrounds the conductor (2a), wherein the superconducting cable (1) has a core with a superconducting conductor (5) and a layer of insulation that surrounds the conductor (5), and wherein the core is arranged in such a way that it can move longitudinally in a cryostat. The conductor (2a) of the terminal structure (2) is electrically connected with the superconducting conductor (5) or with a normal conductor (6) that is connected with the superconducting conductor (5) by means of a tubular part (7) made of an electrically conductive material, wherein the superconducting conductor (5) or the normal conductor (6) can slide in the part (7) in the direction of the superconductor.

  3. Termination unit

    Energy Technology Data Exchange (ETDEWEB)

    Traeholt, Chresten; Willen, Dag; Roden, Mark; Tolbert, Jerry C.; Lindsay, David; Fisher, Paul W.; Nielsen, Carsten Thidemann

    2016-05-03

    Cable end section comprises end-parts of N electrical phases/neutral, and a thermally-insulation envelope comprising cooling fluid. The end-parts each comprises a conductor and are arranged with phase 1 innermost, N outermost surrounded by the neutral, electrical insulation being between phases and N and neutral. The end-parts comprise contacting surfaces located sequentially along the longitudinal extension of the end-section. A termination unit has an insulating envelope connected to a cryostat, special parts at both ends comprising an adapter piece at the cable interface and a closing end-piece terminating the envelope in the end-section. The special parts houses an inlet and/or outlet for cooling fluid. The space between an inner wall of the envelope and a central opening of the cable is filled with cooling fluid. The special part at the end connecting to the cryostat houses an inlet or outlet, splitting cooling flow into cable annular flow and termination annular flow.

  4. From Pericles to Plato – from democratic political praxis to totalitarian political philosophy

    Directory of Open Access Journals (Sweden)

    Øjvind Larsen

    2012-03-01

    Full Text Available Plato is normally taken as one of the founders of Western political philosophy, not at least with his Republic. Here, he constructs a hierarchy of forms of governments, beginning with aristocracy at the top as a critical standard for the other forms of governments, and proceeding through timocracy and oligarchy to democracy and tyranny at the bottom. Following Karl Popper, the paper argues that Plato’s is a totalitarian philosophy that emphasizes the similarities between democracy and tyranny, which it considers to be the two worst forms of government. Plato’s denigration of democracy has dominated the tradition of political philosophy until recent times. This paper, however, shows that political philosophy in fact originates in democracy, especially as developed by the sophists and that philosophy is only a form of sophism with a similar origin in ancient Greek democracy. A discussion of Pericles’ funeral oration is used to show that Pericles presented a democratic political philosophy that can serve as a counterpoint to Plato’s political philosophy in the Republic.

  5. Plato's Concept of Justice%论柏拉图的正义观

    Institute of Scientific and Technical Information of China (English)

    刘欣如

    2015-01-01

    本文以柏拉图的作品《申辩》、《斐多》、《理想国》为切入点,论述了正义是在应在的位置上做应做之事、正义的本质是灵魂的一种属性以及正义的产生,并通过作品提供的背景和对话讨论了正义之人和不义之人的区别、正义的种类、正义行为的动机、正义的各种不同状态等问题.%In this paper, the works of Plato,"defense","Phaedo","Utopia"as the starting point, discusses the justice should be done is to do things in a position to be in, the nature of justice is an attribute of the soul, and justice generation, background and dialogue and through providing discussed works of justice and the unrighteous man of distinction, just the kind of moti-vation act of justice, justice of various states and other issues.

  6. Lost in follow-up rates in TRACER, ATLAS ACS 2, TRITON and TRA 2P trials: challenging PLATO mortality rates.

    Science.gov (United States)

    DiNicolantonio, James J; Can, Mehmet Mustafa; Serebruany, Victor L

    2013-04-15

    Extreme rates of vascular and all-cause mortality especially in the clopidogrel arm of the Platelet Inhibition and Patient Outcomes (PLATO) non-USA cohort raise concerns of data integrity, and call for independent verification of vital records in the national death registries. Four recent acute coronary syndrome (ACS) trials: Thrombin Receptor Antagonist for Clinical Event Reduction in Acute Coronary Syndrome (TRACER), Anti-Xa therapy to lower cardiovascular events in addition to standard therapy in subjects with acute coronary syndrome (ATLAS-ACS 2), Trial to Assess Improvement in Therapeutic Outcomes by Optimizing Platelet Inhibition with Prasugrel (TRITON), and the Thrombin Receptor Antagonist in Secondary Prevention of Atherothrombotic Ischemic Events (TRA 2P), provide a valuable opportunity to match lost in follow-up (LIFU) with mortality rates among similar ACS studies. To compare the LIFU from PLATO, TRACER, ATLAS-ACS 2, TRITON-TIMI 38 and TRA 2P trials. The disturbingly high (8.9%-14.7%) LIFU in PLATO was no match to LIFU in TRACER (0.1%), ATLAS ACS 2 (0.3%), TRITON (0.1%) and TRA 2P (0.1%). In fact, such an astronomical (49-147 fold higher) PLATO LIFU rate should result in less mortality compared to the other ACS trials since no event can be reported or adjudicated if the patient has been lost. Adjusting LIFU rate revealed that vascular (5.55%) and all cause (6.05%) mortality in PLATO was even more disparate than in TRACER (3.2% and 4.9%), ATLAS-ACS 2 (4.1% and 4.5%), TRITON-TIMI 38 (2.4% and 3.2%) and TRA 2P (3.0% and 5.3%) control arms, respectfully. Moreover, the incomplete CV follow-up in the ATLAS ACS 2 trial was later revealed to be around 12%, which lead to the rejection of rivaroxaban for the treatment of ACS. PLATO's LIFU rate was just as high, if not higher, than seen in ATLAS ACS 2. The chance to die in PLATO far exceeds the mortality risks observed in the clopidogrel arms of four recent ACS trials, which becomes especially evident after

  7. Terminal ballistics

    CERN Document Server

    Rosenberg, Zvi

    2016-01-01

    This book comprehensively discusses essential aspects of terminal ballistics, combining experimental data, numerical simulations and analytical modeling. Employing a unique approach to numerical simulations as a measure of sensitivity for the major physical parameters, the new edition also includes the following features: new figures to better illustrate the problems discussed; improved explanations for the equation of state of a solid and for the cavity expansion process; new data concerning the Kolsky bar test; and a discussion of analytical modeling for the hole diameter in a thin metallic plate impacted by a shaped charge jet. The section on thick concrete targets penetrated by rigid projectiles has now been expanded to include the latest findings, and two new sections have been added: one on a novel approach to the perforation of thin concrete slabs, and one on testing the failure of thin metallic plates using a hydrodynamic ram.

  8. Dosimetric evaluation of PLATO and Oncentra treatment planning systems for High Dose Rate (HDR) brachytherapy gynecological treatments

    Science.gov (United States)

    Singh, Hardev; Herman, Tania De La Fuente; Showalter, Barry; Thompson, Spencer J.; Syzek, Elizabeth J.; Herman, Terence; Ahmad, Salahuddin

    2012-10-01

    This study compares the dosimetric differences in HDR brachytherapy treatment plans calculated with Nucletron's PLATO and Oncentra MasterPlan treatment planning systems (TPS). Ten patients (1 T1b, 1 T2a, 6 T2b, 2 T4) having cervical carcinoma, median age of 43.5 years (range, 34-79 years) treated with tandem & ring applicator in our institution were selected retrospectively for this study. For both Plato and Oncentra TPS, the same orthogonal films anterior-posterior (AP) and lateral were used to manually draw the prescription and anatomical points using definitions from the Manchester system and recommendations from the ICRU report 38. Data input for PLATO was done using a digitizer and Epson Expression 10000XL scanner was used for Oncentra where the points were selected on the images in the screen. The prescription doses for these patients were 30 Gy to points right A (RA) and left A (LA) delivered in 5 fractions with Ir-192 HDR source. Two arrangements: one dwell position and two dwell positions on the tandem were used for dose calculation. The doses to the patient points right B (RB) and left B (LB), and to the organs at risk (OAR), bladder and rectum for each patient were calculated. The mean dose and the mean percentage difference in dose calculated by the two treatment planning systems were compared. Paired t-tests were used for statistical analysis. No significant differences in mean RB, LB, bladder and rectum doses were found with p-values > 0.14. The mean percent difference of doses in RB, LB, bladder and rectum are found to be less than 2.2%, 1.8%, 1.3% and 2.2%, respectively. Dose calculations based on the two different treatment planning systems were found to be consistent and the treatment plans can be made with either system in our department without any concern.

  9. Dosimetric evaluation of PLATO and Oncentra treatment planning systems for High Dose Rate (HDR) brachytherapy gynecological treatments

    Energy Technology Data Exchange (ETDEWEB)

    Singh, Hardev; De La Fuente Herman, Tania; Showalter, Barry; Thompson, Spencer J.; Syzek, Elizabeth J.; Herman, Terence; Ahmad, Salahuddin [Department of Radiation Oncology, Peggy and Charles Stephenson Oklahoma Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104 (United States)

    2012-10-23

    This study compares the dosimetric differences in HDR brachytherapy treatment plans calculated with Nucletron's PLATO and Oncentra MasterPlan treatment planning systems (TPS). Ten patients (1 T1b, 1 T2a, 6 T2b, 2 T4) having cervical carcinoma, median age of 43.5 years (range, 34-79 years) treated with tandem and ring applicator in our institution were selected retrospectively for this study. For both Plato and Oncentra TPS, the same orthogonal films anterior-posterior (AP) and lateral were used to manually draw the prescription and anatomical points using definitions from the Manchester system and recommendations from the ICRU report 38. Data input for PLATO was done using a digitizer and Epson Expression 10000XL scanner was used for Oncentra where the points were selected on the images in the screen. The prescription doses for these patients were 30 Gy to points right A (RA) and left A (LA) delivered in 5 fractions with Ir-192 HDR source. Two arrangements: one dwell position and two dwell positions on the tandem were used for dose calculation. The doses to the patient points right B (RB) and left B (LB), and to the organs at risk (OAR), bladder and rectum for each patient were calculated. The mean dose and the mean percentage difference in dose calculated by the two treatment planning systems were compared. Paired t-tests were used for statistical analysis. No significant differences in mean RB, LB, bladder and rectum doses were found with p-values > 0.14. The mean percent difference of doses in RB, LB, bladder and rectum are found to be less than 2.2%, 1.8%, 1.3% and 2.2%, respectively. Dose calculations based on the two different treatment planning systems were found to be consistent and the treatment plans can be made with either system in our department without any concern.

  10. Ancient philosophical ideas of the soul (Plato-Aristotelian tradition and Stoicism as a source of Patristic Thought

    Directory of Open Access Journals (Sweden)

    Zaitsev Cornelius

    2014-10-01

    Full Text Available The article discusses the ancient idea of the soul that in the patristic era has been enriched by the perception of the methodology of ancient philosophy. Greek and Roman thinkers considered some properties of the soul, its immortality, revealed its “levels and strata” (Plato, Aristotle, expressed first guesses about the nature of sinful passions (the Stoics. But some aspects still remained unresolved so far. This is the issue of materiality or immateriality, of the soul, which "raised" in the Russian Empire in the 19th century (the dispute saints Theophan the Recluse and Ignatius Brianchaninov and remains relevant today.

  11. Toward a Poeticognosis: Re-reading Plato's The Republic via Wallace Stevens' "An Ordinary Evening in New Haven"

    Directory of Open Access Journals (Sweden)

    Dan Disney

    2008-01-01

    Full Text Available This article is a language-based re-reading of Plato's exile of the poets via Wallace Stevens' poem-manifesto, "An Ordinary Evening in New Haven." I examine how philosophy and poetry use language differently in order to deconstruct an origin of the speech-acts -- wonder -- that I then identify as a phenomenological difference between philosophers and poets. I contend that the thinking-into-language of philosophers is based in theoria, comprehension, and a resulting closure of wonder. I contrast this with the processes of poets, who I show to be moving thought into language via gnosis, apprehension, and a phenomenology opening onto inexhaustible wonder.

  12. Love and/in psychoanalysis: a commentary on Lacan's reading of Plato's Symposium in Seminar VIII: Transference.

    Science.gov (United States)

    Fink, Bruce

    2015-02-01

    What is love and what part does it play in psychoanalysis? Where are the analyst and the analysand situated in relation to the roles defined as those of the "lover" and the "beloved"? Jacques Lacan explores these and other questions in his soon-to-be-published Seminar VIII: Transference by providing an extensive commentary on Plato's most famous dialogue on love, the Symposium. This paper outlines some of the major points about love that grow out of Lacan's reading of the dialogue and examines their relevance to the analytic setting. Can the analyst be characterized as a sort of modern-day Socrates?

  13. Characterization of human and mouse peroxiredoxin IV: Evidence for inhibition by Prx-IV of epidermal growth factor- and p53-induced reactive oxygen species

    OpenAIRE

    Wong, CM; Kok, KH; Jin, DY; Chun, ACS; Zhou, Y.; Fung, PCW; Kung, HF; Jeang, KT

    2000-01-01

    The aim of this study was to identify and characterize human and mouse Prx-IV. We identified mouse peroxiredoxin IV (Prx-IV) by virtue of sequence homology to its human ortholog previously called AOE372. Mouse Prx-IV conserves an amino-terminal presequence coding for signal peptide. The amino acid sequences of mature mouse and human Prx-IV share 97.5% identity. Phylogenetic analysis demonstrates that Prx-IV is more closely related to Prx-I/-II/-III than to Prx-V/-VI. Previously, we mapped the...

  14. ¿Solamente platos? Cerámicas de barniz rojo en el depósito ibérico del Zacatín (Granada)

    OpenAIRE

    Sánchez Moreno, Amparo; Niveau de Villedary y Mariñas, Ana María; Adroher Auroux, Andrés María

    2015-01-01

    Se presenta un conjunto homogéneo de platos de barniz rojo indígena con un perfil muy particular y sin paralelos conocidos por el momento. Dicho conjunto formaba parte del depósito ritual hallado en la granadina calle del Zacatín, una fosa junto al río Darro que se rellenó con los resultantes de un festín sagrado posiblemente en relación con el propio río. En este trabajo planteamos que estos platos fueron fabricados ex profeso para el ritual que tuvo lugar fuera de las murallas de Iliberri e...

  15. Enhanced Flight Termination System Study Phase I - IV Reports

    Science.gov (United States)

    2002-11-01

    manufactured by Zeta ( EPSCO ) Corp. The CTS equipment is remotely activated by the RSO in the mission control area. The CTS hardware is similar to the...Command Panel System Operations and Maintenance Manual, August 1998. 14. ZETA ( EPSCO ) Command Transmitter System Maintenance Manual for Model 1376...Command Panel System Operations and Maintenance Manual, August 1998. 14. ZETA ( EPSCO ) Command Transmitter System Maintenance Manual for Model 1376

  16. 25 CFR 11.1114 - Termination.

    Science.gov (United States)

    2010-04-01

    ... by the parents or guardian of the child. The petition shall state: (1) The name, birth date, and... functions; (iii) The parent(s) has subjected the minor to willful and repeated acts of sexual abuse; (iv... Minor-in-Need-of-Care Procedure § 11.1114 Termination. (a) Parental rights to a child may be...

  17. The micro-fascism of Plato's good citizen: producing (dis)order through the construction of risk.

    Science.gov (United States)

    O'Byrne, Patrick; Holmes, Dave

    2007-04-01

    The human body has come to be seen as forever susceptible to both external and internal hazards, which in many circumstances require immediate, heroic, and expensive intervention. In response to this, there has been a shift from a treatment-based healthcare model to one of prevention wherein nurses play an integral role by identifying and assessing risks for individuals, communities, and populations. This paper uses Deborah Lupton's outline of the spectrum of risk and applies the theoretical works of Foucault and Plato to demonstrate the means by which nurses maintain social order by identifying and counselling risk takers. It also utilizes the work of Deleuze and Guattari to illustrate how Plato's framework for creating social order through the creation of the good citizen can be viewed as a micro-fascist system, which has been adopted wholeheartedly by preventative health professionals. The goal of this paper is to present an alternate understanding of risk to provide nurses and other healthcare professionals with a non-traditional appreciation of certain aspects of their practice as researchers and clinicians.

  18. Negação e diferença em Platão Negation and diference in Plato

    Directory of Open Access Journals (Sweden)

    Eliane Christina de Souza

    2010-01-01

    Full Text Available Platão, ao tratar da negação no diálogo Sofista, afirma que sempre que enunciamos o que não é, não enunciamos algo contrário ao que é, mas algo diferente. A negação significa cada parte da natureza da diferença em antítese ao que é. Tal tratamento da negação resulta da necessidade de resolver alguns problemas colocados pelo eleatismo. Propõe-se indicar esses problemas e examinar o tratamento que Platão dá ao não-ser como diferença.Plato, in dealing with negation in the dialogue Sophist, says that when we say what is not, we speak not of something that is the opposite of being, but of something different. Negation means each part of the nature of the difference in antithesis to what is. This treatment of negation results from the need to solve some problems posed by eleatism. It is proposed to indicate these problems and examine the treatment that Plato gives to non-being as difference.

  19. Comparative Study of Meanings and Status of Imagination in Mathnavi and Plato’s Ideas

    Directory of Open Access Journals (Sweden)

    sh alyari

    2013-02-01

    Full Text Available Describing and explaining the nature of imagination and its function with regard to human being and ontology has always been one of the preoccupations of philosophers and thinkers. Plato is the first philosopher who considered an epistemological status for imagination and, by dividing the world into the world of reason and world of senses, he ascribed the knowledge of imagination to the world of senses. In different parts of Mathnavi, Molavi, the great Muslim-Iranian mystic, has paid much attention to imagination, its types, its status in the Knowledge of Man (both physical and metaphysical affairs and its various influences on the body, soul and mental states of any individual. Thus, the present article aims to compare the concept of imagination in the view of the two thinkers. For reaching such aim, while using a descriptive-comparative method, first, the definitions of imagination in Mathnavi and Plato’s ideas are investigated and, then, the similarities and differences of the two views are shown. The conclusion is that their ideas are similar with regard to unreality and shadowiness of the world and phenomena, the relation between imitation and imagination, deficiency and restrictions of imagination for understanding the reality, whereas their ideas are different regarding the power of imagination, its epistemological status and the meaning and influence of it.

  20. Topological characterisation and identification of critical domains within glucosyltransferase IV (GtrIV of Shigella flexneri

    Directory of Open Access Journals (Sweden)

    Nair Anesh

    2011-12-01

    Full Text Available Abstract Background The three bacteriophage genes gtrA, gtrB and gtr(type are responsible for O-antigen glucosylation in Shigella flexneri. Both gtrA and gtrB have been demonstrated to be highly conserved and interchangeable among serotypes while gtr(type was found to be specific to each serotype, leading to the hypothesis that the Gtr(type proteins are responsible for attaching glucosyl groups to the O-antigen in a site- and serotype- specific manner. Based on the confirmed topologies of GtrI, GtrII and GtrV, such interaction and attachment of the glucosyl groups to the O-antigen has been postulated to occur in the periplasm. Results In this study, the topology of GtrIV was experimentally determined by creating different fusions between GtrIV and a dual-reporter protein, PhoA/LacZ. This study shows that GtrIV consists of 8 transmembrane helices, 2 large periplasmic loops, 2 small cytoplasmic N- and C- terminal ends and a re-entrant loop that occurs between transmembrane helices III and IV. Though this topology differs from that of GtrI, GtrII, GtrV and GtrX, it is very similar to that of GtrIc. Furthermore, both the N-terminal periplasmic and the C-terminal periplasmic loops are important for GtrIV function as shown via a series of loop deletion experiments and the creation of chimeric proteins between GtrIV and its closest structural homologue, GtrIc. Conclusion The current study provides the basis for elucidating the structure and mechanism of action of this important O-antigen modifying glucosyltransferase.

  1. The Case against the Arts from Plato to Tolstoy and Its Implications for Why and How the Arts Should Be Taught in Schools

    Science.gov (United States)

    Tate, Nicholas

    2016-01-01

    From Plato onwards many of the great Western thinkers have explored the nature of the arts, their contribution to society and their role in education. This has often involved a discussion of the potentially negative impact of the arts. The recurring message has been that the arts can warp judgment, elevate emotion at the expense of reason,…

  2. Why Did Socrates Deny That He Was a Teacher? Locating Socrates among the New Educators and the Traditional Education in Plato's "Apology of Socrates"

    Science.gov (United States)

    Mintz, Avi I.

    2014-01-01

    Plato's "Apology of Socrates" contains a spirited account of Socrates' relationship with the city of Athens and its citizens. As Socrates stands on trial for corrupting the youth, surprisingly, he does not defend the substance and the methods of his teaching. Instead, he simply denies that he is a teacher. Many scholars have…

  3. Cardiovascular events in acute coronary syndrome patients with peripheral arterial disease treated with ticagrelor compared to clopidogrel: Data from the PLATO trials

    DEFF Research Database (Denmark)

    Patel, Manesh R.; Becker, Richard C.; Wojdyla, Daniel M.;

    Abstract 14299: Cardiovascular Events in Acute Coronary Syndrome Patients With Peripheral Arterial Disease Treated With Ticagrelor Compared to Clopidogrel: Data From the PLATO Trial Manesh R Patel1; Richard C Becker1; Daniel M Wojdyla2; Håkan Emanuelsson3; William Hiatt4; Jay Horrow5; Steen Husted6...

  4. Aging, Terminal Decline, and Terminal Drop

    Science.gov (United States)

    Palmore, Erdman; Cleveland, William

    1976-01-01

    Data from a 20-year longitudinal study of persons over 60 were analyzed by step-wise multiple regression to test for declines in function with age, for terminal decline (linear relationship to time before death), and for terminal drop (curvilinear relationship to time before death). There were no substantial terminal drop effects. (Author)

  5. NNDSS - Table IV. Tuberculosis

    Data.gov (United States)

    U.S. Department of Health & Human Services — NNDSS - Table IV. Tuberculosis - 2014.This Table includes total number of cases reported in the United States, by region and by states, in accordance with the...

  6. NNDSS - Table IV. Tuberculosis

    Data.gov (United States)

    U.S. Department of Health & Human Services — NNDSS - Table IV. Tuberculosis - 2016.This Table includes total number of cases reported in the United States, by region and by states, in accordance with the...

  7. NNDSS - Table IV. Tuberculosis

    Data.gov (United States)

    U.S. Department of Health & Human Services — NNDSS - Table IV. Tuberculosis - 2015.This Table includes total number of cases reported in the United States, by region and by states, in accordance with the...

  8. Interplanetary Type IV Bursts

    CERN Document Server

    Hillaris, Alexander; Nindos, Alexander

    2016-01-01

    In this work we study the characteristics of moving type IV radio bursts which extend to the hectometric wavelengths (interplanetary type IV or type IV IP bursts) and their relationship with energetic phenomena on the Sun. Our dataset comprised 48 Interplanetary type IV bursts observed by the Wind/WAVES in the 13.825 MHz?20 KHz frequency range. The dynamic spec tra of the RSTN, DAM, ARTEMIS-IV, CULGOORA, Hiraiso and IZMIRAN Radio-spectrographs were used to track the evolution of the events in the low corona; these were supplemented with SXR ?ux recordings from GOES and CME data from LASCO. Positional information for the coronal bursts were obtained by the Nan\\c{c}ay radioheliograph (NRH). We examined the relationship of the type IV events with coronal radio bursts, CMEs and SXR ?ares. The majority of the events (45) were characterized as compact; their duration was on average 106 min. This type of events were, mostly, associated with M and X class ?ares (40 out of 45) and fast CMEs; 32 of these events had CME...

  9. Interplanetary Type IV Bursts

    Science.gov (United States)

    Hillaris, A.; Bouratzis, C.; Nindos, A.

    2016-08-01

    We study the characteristics of moving type IV radio bursts that extend to hectometric wavelengths (interplanetary type IV or type {IV}_{{IP}} bursts) and their relationship with energetic phenomena on the Sun. Our dataset comprises 48 interplanetary type IV bursts observed with the Radio and Plasma Wave Investigation (WAVES) instrument onboard Wind in the 13.825 MHz - 20 kHz frequency range. The dynamic spectra of the Radio Solar Telescope Network (RSTN), the Nançay Decametric Array (DAM), the Appareil de Routine pour le Traitement et l' Enregistrement Magnetique de l' Information Spectral (ARTEMIS-IV), the Culgoora, Hiraso, and the Institute of Terrestrial Magnetism, Ionosphere and Radio Wave Propagation (IZMIRAN) Radio Spectrographs were used to track the evolution of the events in the low corona. These were supplemented with soft X-ray (SXR) flux-measurements from the Geostationary Operational Environmental Satellite (GOES) and coronal mass ejections (CME) data from the Large Angle and Spectroscopic Coronagraph (LASCO) onboard the Solar and Heliospheric Observatory (SOHO). Positional information of the coronal bursts was obtained by the Nançay Radioheliograph (NRH). We examined the relationship of the type IV events with coronal radio bursts, CMEs, and SXR flares. The majority of the events (45) were characterized as compact, their duration was on average 106 minutes. This type of events was, mostly, associated with M- and X-class flares (40 out of 45) and fast CMEs, 32 of these events had CMEs faster than 1000 km s^{-1}. Furthermore, in 43 compact events the CME was possibly subjected to reduced aerodynamic drag as it was propagating in the wake of a previous CME. A minority (three) of long-lived type {IV}_{{IP}} bursts was detected, with durations from 960 minutes to 115 hours. These events are referred to as extended or long duration and appear to replenish their energetic electron content, possibly from electrons escaping from the corresponding coronal

  10. DNA Ligase IV regulates XRCC4 nuclear localization.

    Science.gov (United States)

    Francis, Dailia B; Kozlov, Mikhail; Chavez, Jose; Chu, Jennifer; Malu, Shruti; Hanna, Mary; Cortes, Patricia

    2014-09-01

    DNA Ligase IV, along with its interacting partner XRCC4, are essential for repairing DNA double strand breaks by non-homologous end joining (NHEJ). Together, they complete the final ligation step resolving the DNA break. Ligase IV is regulated by XRCC4 and XLF. However, the mechanism(s) by which Ligase IV control the NHEJ reaction and other NHEJ factor(s) remains poorly characterized. Here, we show that a C-terminal region of Ligase IV (aa 620-800), which encompasses a NLS, the BRCT I, and the XRCC4 interacting region (XIR), is essential for nuclear localization of its co-factor XRCC4. In Ligase IV deficient cells, XRCC4 showed deregulated localization remaining in the cytosol even after induction of DNA double strand breaks. DNA Ligase IV was also required for efficient localization of XLF into the nucleus. Additionally, human fibroblasts that harbor hypomorphic mutations within the Ligase IV gene displayed decreased levels of XRCC4 protein, implicating that DNA Ligase IV is also regulating XRCC4 stability. Our results provide evidence for a role of DNA Ligase IV in controlling the cellular localization and protein levels of XRCC4.

  11. IV access in dental practice.

    LENUS (Irish Health Repository)

    Fitzpatrick, J J

    2009-04-01

    Intravenous (IV) access is a valuable skill for dental practitioners in emergency situations and in IV sedation. However, many people feel some apprehension about performing this procedure. This article explains the basic principles behind IV access, and the relevant anatomy and physiology, as well as giving a step-by-step guide to placing an IV cannula.

  12. Dibromidodimethyldipyridineplatinum(IV

    Directory of Open Access Journals (Sweden)

    Mairéad E. Kelly

    2008-11-01

    Full Text Available In the title complex, [PtBr2(CH32(C5H5N2], the PtIV metal centre lies on a twofold rotation axis and adopts a slightly distorted octahedral coordination geometry. The structure displays weak intramolecular C—H...Br hydrogen-bonding interactions.

  13. Marketing produktu Karel IV.

    OpenAIRE

    Mikšů, Šárka

    2009-01-01

    Goal of the thesis Marketing of the product Karel IV. is to propose chanels of marketing communication and indicate possibilities of next product's development. Theoretical part is based on marketing plan and it's partition. In the practical part you can find market analysis and competing products analysis, product's evolution description and marketing research.

  14. The Operational Planner and War Termination

    Science.gov (United States)

    1993-02-22

    Termination: Campaign Plan Format ................... 16 IV THE CLARKE MODEL ......................................... 18 Critica .. Guidance...periods of crisis . Consequently, the military aim has all to often become the national policy--an end in itself, instead of as merely a means to the end.1...capabilities. Also, consider the influence of and advantages to strategic by-standers not directly a party to the crisis . (4) Conclusions Regarding

  15. Republican Utopia:from Plato to Moore%共和主义乌托邦:从柏拉图到莫尔

    Institute of Scientific and Technical Information of China (English)

    徐百军

    2012-01-01

    通过对柏拉图的《理想国》和莫尔的《乌托邦》的文本分析,我们发现他们的乌托邦思想中潜藏着共和主义叙事,实质上柏拉图和莫尔都希图建构一种共和主义乌托邦,由此也可以说乌托邦思想与共和主义之间原本就存在着一种共生的却被遗忘的历史关系,因而我们试图恢复以柏拉图和莫尔为代表的乌托邦思想家在共和主义政治光谱中的理论地位也并非一种主观冲动。%Through making a text analysis of Plato's Republic and Moore's Utopia,we find that a republican narrative has been hidden in their Utopian thought.Essencially,Plato and Moore both hoped to construct a republican utopia.It also can be said that there is a symbiotic and forgotten historical relation between the utopian thought and republicanism.So it is not a subjective impulse that we try to give the theoretical status in the republican political spectrum back to the utopian thinkers whose representatives are Plato and Moore.

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    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

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    Data.gov (United States)

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  7. paen Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  11. kafw Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  12. kabq Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  18. ktpa Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  7. Terminated Multifamily Mortgages Database

    Data.gov (United States)

    Department of Housing and Urban Development — Includes all terminated HUD Multifamily insured mortgages. It includes the Holder and Servicer at the time the mortgage was terminated. The data is good as of...

  8. Terminated Multifamily Mortgages Database

    Data.gov (United States)

    Department of Housing and Urban Development — This Excel 2010 file includes all terminated HUD Multifamily insured mortgages. It includes the Holder and Servicer at the time the mortgage was terminated. The data...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

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    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  13. ksoa Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  14. paom Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  15. kgmu Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  16. khya Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  17. kjfk Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  18. kpie Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  19. kpns Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  20. ksat Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  1. kcid Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  2. ksny Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  3. klch Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  4. khnd Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  5. ksaf Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  6. kdec Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  7. ktvl Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  8. kttd Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  9. kluk Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  10. ksdf Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  11. krno Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  12. kwwr Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  13. kowb Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  14. kcle Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  15. kcxp Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  16. kgpi Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  17. paun Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  18. keat Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  19. pasc Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  20. koun Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  1. klee Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  2. kiag Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  3. kbmg Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  4. pakn Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  5. kmmh Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  6. kiln Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  7. kbmi Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  8. kcha Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  9. pahn Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  10. khon Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  11. kpeq Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  12. kden Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  13. kmia Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  14. kmaf Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  15. khsa Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  16. kvis Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  17. ktcl Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  18. kmrb Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  19. kcub Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  20. kpdt Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  1. ptkk Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  2. kcsm Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  3. ksfo Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  4. kjhw Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  5. kdab Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  6. kecp Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  7. kmls Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  8. kroc Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  9. kfod Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  10. khdn Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  11. pabe Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  12. ktop Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  13. ktrk Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  14. krvs Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  15. kgld Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  16. kama Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  17. kmgm Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  18. The great Lisbon earthquake and tsunami of 1755: lessons from the recent Sumatra earthquakes and possible link to Plato's Atlantis

    Science.gov (United States)

    Gutscher, M.-A.

    2006-05-01

    Great earthquakes and tsunami can have a tremendous societal impact. The Lisbon earthquake and tsunami of 1755 caused tens of thousands of deaths in Portugal, Spain and NW Morocco. Felt as far as Hamburg and the Azores islands, its magnitude is estimated to be 8.5 9. However, because of the complex tectonics in Southern Iberia, the fault that produced the earthquake has not yet been clearly identified. Recently acquired data from the Gulf of Cadiz area (tomography, seismic profiles, high-resolution bathymetry, sampled active mud volcanoes) provide strong evidence for an active east dipping subduction zone beneath Gibraltar. Eleven out of 12 of the strongest earthquakes (M>8.5) of the past 100 years occurred along subduction zone megathrusts (including the December 2004 and March 2005 Sumatra earthquakes). Thus, it appears likely that the 1755 earthquake and tsunami were generated in a similar fashion, along the shallow east-dipping subduction fault plane. This implies that the Cadiz subduction zone is locked (like the Cascadia and Nankai/Japan subduction zones), with great earthquakes occurring over long return periods. Indeed, the regional paleoseismic record (contained in deep-water turbidites and shallow lagoon deposits) suggests great earthquakes off South West Iberia every 1500 2000 years. Tsunami deposits indicate an earlier great earthquake struck SW Iberia around 200 BC, as noted by Roman records from Cadiz. A written record of even older events may also exist. According to Plato's dialogues The Critias and The Timaeus, Atlantis was destroyed by ‘strong earthquakes and floods … in a single day and night’ at a date given as 11,600 BP. A 1 m thick turbidite deposit, containing coarse grained sediments from underwater avalanches, has been dated at 12,000 BP and may correspond to the destructive earthquake and tsunami described by Plato. The effects on a paleo-island (Spartel) in the straits of Gibraltar would have been devastating, if inhabited, and may

  19. Enhanced Design Alternative IV

    Energy Technology Data Exchange (ETDEWEB)

    N. E. Kramer

    1999-05-18

    This report evaluates Enhanced Design Alternative (EDA) IV as part of the second phase of the License Application Design Selection (LADS) effort. The EDA IV concept was compared to the VA reference design using criteria from the ''Design Input Request for LADS Phase II EDA Evaluations'' (CRWMS M&O 1999b) and (CRWMS M&O 1999f). Briefly, the EDA IV concept arranges the waste packages close together in an emplacement configuration known as ''line load''. Continuous pre-closure ventilation keeps the waste packages from exceeding the 350 C cladding and 200 C (4.3.13) drift wall temperature limits. This EDA concept keeps relatively high, uniform emplacement drift temperatures (post-closure) to drive water away from the repository and thus dry out the pillars between emplacement drifts. The waste package is shielded to permit human access to emplacement drifts and includes an integral filler inside the package to reduce the amount of water that can contact the waste form. Closure of the repository is desired 50 years after first waste is emplaced. Both backfill and a drip shields will be emplaced at closure to improve post-closure performance.

  20. 49 CFR 1242.27 - Coal marine terminals, ore marine terminals, TOFC/COFC terminals, other marine terminals, motor...

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Coal marine terminals, ore marine terminals, TOFC/COFC terminals, other marine terminals, motor vehicle loading and distribution facilities, and... Structures § 1242.27 Coal marine terminals, ore marine terminals, TOFC/COFC terminals, other marine...

  1. Organizational Relationship Termination Competence

    DEFF Research Database (Denmark)

    Ritter, Thomas; Geersbro, Jens

    2011-01-01

    that a firm's percentage of unwanted customers decreases significantly as acceptance of termination increases, if the firm's definition of unwanted customers is well understood, and if a firm has clear termination routines. In addition, general focus on profitability and external constraints on relationship...... termination are found to significantly affect a firm's relationship termination competence. The findings suggest that managers should regard termination as a legitimate option in customer relationship management. In order to decrease the number of unwanted customers, managers must accept termination......Most firms are involved in a number of customer relationships that drain the firm's resources. However, many firms are hesitant to address this problem. This paper investigates customer relationship termination at the organizational level. We develop and analyze the organizational dimensions...

  2. A dialogical exploration of the grey zone of health and illness: medical science, anthropology, and Plato on alcohol consumption.

    Science.gov (United States)

    Bonner, Kieran

    2009-01-01

    This paper takes a phenomenological hermeneutic orientation to explicate and explore the notion of the grey zone of health and illness and seeks to develop the concept through an examination of the case of alcohol consumption. The grey zone is an interpretive area referring to the irremediable zone of ambiguity that haunts even the most apparently resolute discourse. This idea points to an ontological indeterminacy, in the face of which decisions have to be made with regard to the health of a person (e.g., an alcoholic), a system (e.g., the health system), or a society. The fundamental character of this notion will be developed in relation to the discourse on health and the limitations of different disciplinary practices. The case of alcohol consumption will be used to tease out the grey zone embedded in the different kinds of knowledge made available through the disciplinary traditions of medical science, with its emphasis on somatic well-being, and anthropology, with its focus on communal well-being. This tension or grey zone embedded in different knowledge outcomes will be shown to have a discursive parallel with the dialogue between the Athenian, the Spartan, and the Cretan in Plato's Laws. Making use of the dialogical approach as described by Gadamer, the Athenian's particular resolution of the tension will be explored as a case study to demonstrate the necessarily particular analysis involved in a grey zone resolution.

  3. What is good sport: Plato's view Co je to dobrý sport: Platónův pohled

    Directory of Open Access Journals (Sweden)

    Jernej Pisk

    2006-02-01

    Full Text Available One of Plato's most common questions found in his dialogues is "What is something?" By asking this question Plato usually brought his co-speakers to the recognition that in fact they do not have a full comprehension of what something is, although they have a partial comprehension of it. The awareness of one's incomplete cognition is the first step to be made on the philosophic way to truth. As in ancient times also today Plato asks us – the modern philosophers of sport – "What is sport?" or more precisely "What is good sport?" Probably the best of Plato's answers to this question can be found in the basic concepts of his philosophy regarding his hierarchical division of the state and human soul into three parts. Since sport is derived from human being also the goodness of sport can be divided into three stages. The lowest stage of sport corresponds to the first part of the soul – the appetite soul. On this stage sport is based on the gaining of material goods through prizes won at competitions. In the philosophic view, this is the lowest possible stage of goodness of sport. The second stage of sport corresponds to the second part of the soul – the emotional soul. Sport at this stage is based on the elementary ancient agon, which seeks fulfilment in the winning of honour and glory. The greatest and the most superior is the third part of the soul – the reasonable soul. According to this, also the sport corresponding to the third part of the soul is the best. For this kind of sport it is no longer necessary to compete with other contestants, since it can achieve it's fulfilment in perfect execution of movement or exercise, in which the perfect cooperation between reason (soul and body is attained. At this stage of sport it is the most important to compete and win over one's self, and this can be achieved by everyone, without regard to his/her physical abilities in comparison with others. In Plato's view, good sport is the sport directed

  4. Characterization of human and mouse peroxiredoxin IV: evidence for inhibition by Prx-IV of epidermal growth factor- and p53-induced reactive oxygen species.

    Science.gov (United States)

    Wong, C M; Chun, A C; Kok, K H; Zhou, Y; Fung, P C; Kung, H F; Jeang, K T; Jin, D Y

    2000-01-01

    The aim of this study was to identify and characterize human and mouse Prx-IV. We identified mouse peroxiredoxin IV (Prx-IV) by virtue of sequence homology to its human ortholog previously called AOE372. Mouse Prx-IV conserves an amino-terminal presequence coding for signal peptide. The amino acid sequences of mature mouse and human Prx-IV share 97.5% identity. Phylogenetic analysis demonstrates that Prx-IV is more closely related to Prx-I/-II/-III than to Prx-V/-VI. Previously, we mapped the mouse Prx-IV gene to chromosome X by analyzing two sets of multiloci genetic crosses. Here we performed further comparative analysis of mouse and human Prx-IV genomic loci. Consistent with the mouse results, human Prx-IV gene localized to chromosome Xp22.135-136, in close proximity to SAT and DXS7178. A bacterial artificial chromosome (BAC) clone containing the complete human Prx-IV locus was identified. The size of 7 exons and the sequences of the splice junctions were confirmed by PCR analysis. We conclude that mouse Prx-IV is abundantly expressed in many tissues. However, we could not detect Prx-IV in the conditioned media of NIH-3T3 and Jurkat cells. Mouse Prx-IV was specifically found in the nucleus-excluded region of cultured mouse cells. Intracellularly, overexpression of mouse Prx-IV prevented the production of reactive oxygen species induced by epidermal growth factor or p53. Taken together, mouse Prx-IV is likely a cytoplasmic or organellar peroxiredoxin involved in intracellular redox signaling.

  5. CONTAINER TERMINALS IN EUROPE

    Directory of Open Access Journals (Sweden)

    Bart W. WIEGMANS

    2001-01-01

    Full Text Available This paper aims to address the linkage between logistics (in particular, the management of marketing channel flows and transport markets, while also the interaction between these two markets and intermodal container terminals is analysed. The marketing channel theory is used to describe all relevant actors and flows that run through marketing channels, starting with customer needs and ending with customer satisfaction. Porter's theory of competitive advantages is used to review competitive forces in both markets. Finally, a competitor analysis is performed for the logistics and transport market. These theories are applied so as to be able to determine the competitive position of intermodal container terminals with a view to the management of marketing channel flows and the physical transport of freight flows. Hence, the central question of this paper is: Which markets are served by intermodal container terminals and with whom are they competing? At present, neither the maritime container terminals nor the continental container terminals appear to have a significant influence in the logistics service market; they concentrate mainly on the physical movement of containers (transshipment. Furthermore, maritime container terminals and continental container terminals are not dominant players in the transport service market. Our conclusion is that continental terminals are predominantly competing with unimodal road transport, with neighbouring continental terminals and with barge transport companies.

  6. Diaquatetrabromidotin(IV trihydrate

    Directory of Open Access Journals (Sweden)

    Fei Ye

    2012-09-01

    Full Text Available The title compound, [SnBr4(H2O2]·3H2O, forms large colourless crystals in originally sealed samples of tin tetrabromide. It constitutes the first structurally characterized hydrate of SnBr4 and is isostructural with the corresponding hydrate of SnCl4. It is composed of SnIV atoms octahedrally coordinated by four Br atoms and two cis-related water molecules. The octahedra exhibit site symmetry 2. They are arranged into columns along [001] via medium–strong O—H...O hydrogen bonds involving the two lattice water molecules (one situated on a twofold rotation axis while the chains are interconnected via longer O—H...Br hydrogen bonds, forming a three-dimensional network.

  7. The influence of Plato, Aristotle, and the ancient Polis on a programme for congenital cardiac surgery: the virtuous partnership.

    Science.gov (United States)

    Mavroudis, Constantine; Backer, Carl L

    2007-09-01

    The problems that exist in maintaining a partnership in paediatric cardiac surgery are considerable. They relate to fairness in allocation of time for leisure, the apportioning of cases between the partners, internal competition between them, financial considerations, and promotion of the ego. In this review, we discuss our own experiences in maintaining a partnership over a period of more than 18 years, relating such a "virtuous partnership" to the writings of Plato and Aristotle, and setting it against the tenets of the ancient Greek polis. The polis, or city state, came to prominence in ancient Greece during the golden age of Pericles, this period seeing the initial evolution of Western philosophy, as well as numerous other scientific, artistic and architectural advances. The concept of the polis was to create a natural association with its citizens that nurtured all that is best in people, at the same time defining their character. In this respect, according to Plato, the person and the polis are mirror images. Aristotle then expanded this notion to incorporate the various forms of friendship, which he pointed out last only as long as the interrelated pleasure survives. Using these principles as the point of departure, we argue that cardiac surgeons should respect moral virtue in each other. Extending this process means that we should also respect, and celebrate, our relationships with affiliated physicians, nurses, perfusionists, administrators, and all concerned in the care of children with congenitally malformed hearts. In this way, we create a virtuous partnership for congenital cardiac surgery that promotes all that was good, as engendered in the ancient Greek polis. As we extend these observations to the modern world, we discuss some of the features that have permitted us to work so well together. One of the most important is a summoning and unwritten tenet that greets us as we enter the operating room, namely "check your ego at the door". The operative

  8. dBASE IV basics

    Energy Technology Data Exchange (ETDEWEB)

    O`Connor, P.

    1994-09-01

    This is a user`s manual for dBASE IV. dBASE IV is a popular software application that can be used on your personal computer to help organize and maintain your database files. It is actually a set of tools with which you can create, organize, select and manipulate data in a simple yet effective manner. dBASE IV offers three methods of working with the product: (1) control center: (2) command line; and (3) programming.

  9. Phase IV of Drug Development

    OpenAIRE

    Viraj Suvarna

    2010-01-01

    Not all Phase IV studies are post-marketing surveillance (PMS) studies but every PMS study is a phase IV study. Phase IV is also an important phase of drug development. In particular, the real world effectiveness of a drug as evaluated in an observational, non-interventional trial in a naturalistic setting which complements the efficacy data that emanates from a pre-marketing randomized controlled trial (RCT). No matter how many patients are studied pre-marketing in a controlled environment, ...

  10. 34 CFR 668.86 - Limitation or termination proceedings.

    Science.gov (United States)

    2010-07-01

    ... place; and (iv) In the case of a limitation or termination proceeding against a third-party servicer... program or the eligibility of a third-party servicer to contract with any institution to administer any... financial charges, or the employability of its graduates; or (B) In the case of a third-party servicer,...

  11. Confirmatory Factor Analysis of the WAIS-IV/WMS-IV

    Science.gov (United States)

    Holdnack, James A.; Zhou, Xiaobin; Larrabee, Glenn J.; Millis, Scott R.; Salthouse, Timothy A.

    2011-01-01

    The Wechsler Adult Intelligence Scale-fourth edition (WAIS-IV) and the Wechsler Memory Scale-fourth edition (WMS-IV) were co-developed to be used individually or as a combined battery of tests. The independent factor structure of each of the tests has been identified; however, the combined factor structure has yet to be determined. Confirmatory…

  12. Confirmatory Factor Analysis of the WAIS-IV/WMS-IV

    Science.gov (United States)

    Holdnack, James A.; Zhou, Xiaobin; Larrabee, Glenn J.; Millis, Scott R.; Salthouse, Timothy A.

    2011-01-01

    The Wechsler Adult Intelligence Scale-fourth edition (WAIS-IV) and the Wechsler Memory Scale-fourth edition (WMS-IV) were co-developed to be used individually or as a combined battery of tests. The independent factor structure of each of the tests has been identified; however, the combined factor structure has yet to be determined. Confirmatory…

  13. Retrospective study on prognostic importance of serum procalcitonin and amino-terminal pro-brain natriuretic peptide levels as compared to Acute Physiology and Chronic Health Evaluation IV Score on Intensive Care Unit admission, in a mixed Intensive Care Unit population

    OpenAIRE

    2016-01-01

    Background: Timely decision making in Intensive Care Unit (ICU) is very essential to improve the outcome of critically sick patients. Conventional scores like Acute Physiology and Chronic Health Evaluation (APACHE IV) are quite cumbersome with calculations and take minimum 24 hours. Procalcitonin has shown to have prognostic value in ICU/Emergency department (ED) in disease states like pneumonia, sepsis etc. NTproBNP has demonstrated excellent diagnostic and prognostic importance in cardiac d...

  14. DSM-IV Progress Report.

    Science.gov (United States)

    Hohenshil, Thomas H.

    1992-01-01

    Notes that Diagnostic and Statistical Manual of Mental Disorders fourth edition (DSM-IV) will become one of most frequently used reference documents in counseling profession. Describes progress being made in development of DSM-IV, scheduled for publication in 1994. Describes revision process and proposed organizational changes and new diagnostic…

  15. Identification and characterization of a dipeptidyl peptidase IV inhibitor from aronia juice

    Energy Technology Data Exchange (ETDEWEB)

    Kozuka, Miyuki [Department of Health and Nutrition, Faculty of Human Science, Hokkaido Bunkyo University, Eniwa 061-1449 (Japan); Yamane, Takuya, E-mail: t-yamane@pharm.hokudai.ac.jp [Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-ku, Sapporo 060-0812 (Japan); Nakano, Yoshihisa [Center for Research and Development Bioresources, Research Organization for University-Community Collaborations, Osaka Prefecture University, Sakai, Osaka 599-8570 (Japan); Nakagaki, Takenori [Institute of Food Sciences, Nakagaki Consulting Engineer Co., Ltd, Nishi-ku, Sakai 593-8328 (Japan); Ohkubo, Iwao [Department of Nutrition, School of Nursing and Nutrition, Tenshi College, Higashi-ku, Sapporo 065-0013 (Japan); Ariga, Hiroyoshi [Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-ku, Sapporo 060-0812 (Japan)

    2015-09-25

    Aronia berries have many potential effects on health, including an antioxidant effect, effect for antimutagenesis, hepatoprotection and cardioprotection, an antidiabetic effect and inhibition of cancer cell proliferation. Previous human studies have shown that aronia juice may be useful for treatment of obesity disorders. In this study, we found that aronia juice has an inhibitory effect against dipeptidyl peptidase IV (DPP IV) (EC 3.4.14.5). DPP IV is a peptidase that cleaves the N-terminal region of incretins such as glucagon-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1). Inactivation of incretins by DPP IV induces reduction of insulin secretion. Furthermore, we identified that cyanidin 3, 5-diglucoside as the DPP IV inhibitor in aronia juice. DPP IV was inhibited more strongly by cyanidin 3, 5-diglucoside than by cyanidin and cyanidin 3-glucoside. The results suggest that DPP IV is inhibited by cyanidin 3, 5-diglucoside present in aronia juice. The antidiabetic effect of aronia juice may be mediated through DPP IV inhibition by cyanidin 3, 5-diglucoside. - Highlights: • DPP IV activity is inhibited by aronia juice. • DPP IV inhibitor is cyanidin 3, 5-diglucoside in aronia juice. • DPP IV is inhibited by cyanidin 3, 5-diglucoside more than cyanidin and cyanidin 3-glucoside.

  16. Terminal Velocity Infall in QSO Absorption Line Halos

    Science.gov (United States)

    Benjamin, Robert A.

    We explore the hypothesis that clouds detected in quasar absorption line systems are falling at a terminal velocity toward the center of high redshift gaseous galactic halos. Since both the ionization level and terminal velocity of halo clouds increase with increasing distance from the central galaxy, velocity resolved profiles of highly ionized gas are predicted to have a greater width than low ionization gas. A line of sight passing through the center of gaseous halo (an idealized damped Ly alpha system), yields low ionization absorption at the velocity of the galaxy, flanked by high ionization on either side. Reasonable halo parameters yield total velocity extents for C IV of Delta v_{C IV}=100-200 km s^{-1}, in agreement with many systems observed by Lu et al (1997). The remaining systems may better described by the rotating disk model of Prochaska & Wolfe (1998). Finally, observational tests are suggested for verifying or falsifying the terminal velocity hypothesis for these systems.

  17. 29 CFR 2578.1 - Termination of abandoned individual account plans.

    Science.gov (United States)

    2010-07-01

    ... administrator satisfies the requirements of paragraph (d)(2)(iii)(A) of this section. (iv) Engage service... services provided to customers that are not plans terminated pursuant to this section, if the qualified termination administrator (or affiliate) provides same or similar services to such other customers, and...

  18. Misrepresentation of vital status follow-up: challenging the integrity of the PLATO trial and the claimed mortality benefit of ticagrelor versus clopidogrel.

    Science.gov (United States)

    DiNicolantonio, James J; Tomek, Ales

    2013-10-30

    Ticagrelor, a novel, reversible, and oral P2Y12 receptor antagonist, was claimed to reduce all-cause mortality compared to clopidogrel in the PLATO trial. We sought to ascertain vital status follow-up for clopidogrel and ticagrelor to determine if any discrepancy existed by reviewing data from the FDA Complete Response Review. The FDA Complete Response Review indicated misrepresentation of vital status follow-up by the sponsor's presenter at the Cardiovascular and Renal Drugs Advisory Committee. Instead of five patients with missing vital status follow-up, the FDA primary efficacy reviewer indicated that there was a minimum of 106 patients. Additionally and more concerning was the fact that significantly more patients on ticagrelor (3.1%, n = 289 patients) had incomplete vital status follow-up versus clopidogrel (2.6%, n = 242 patients, p = 0.04 for the difference). The Advisory Committee that voted in favor to approve ticagrelor was given misrepresented data, which may have affected the approval of ticagrelor. The fact that significantly more patients on ticagrelor had incomplete vital status follow-up versus clopidogrel challenges the claimed mortality benefit of ticagrelor and the approval of the PLATO trial. © 2013 Elsevier Ireland Ltd. All rights reserved.

  19. Proporción y autoría. Arte mueble paleolítico. Figuras de los Omóplatos de

    Directory of Open Access Journals (Sweden)

    José Antonio Fernández Lombera

    2003-01-01

    Full Text Available El trabajo se compone de las siguientes partes : a.- Realización de calcos con una gran objetividad gráfica de las figuras grabadas en los omóplatos de El Castillo, exhumados por OBERMAIER en sus campañas de 1911/12. b.- Diseño, validación y aplicación de un método para el cálculo de la proporción de una figura, independoentemente de cuál sea, enfrentándola a un arquetipo. c.- Aplicación de tal método, una vez validado, a las figuras de los omóplatos de El Castillo. d.- Análisis de la manera de hacer de cada uno de los autores de las figuras de El Castillo ; es a lo que llamamos autoría. e.- Obtención de un conjunto de conclusiones de tipo formal, artístico y paleoetnológico

  20. Terminated Multifamily Mortgages Database

    Data.gov (United States)

    Department of Housing and Urban Development — This dataset includes all terminated HUD Multifamily mortgages except those from the Hospital Mortgage Insurance Program. It includes the Holder and Servicer at the...

  1. Coal terminal directory

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-06-15

    The directory gives a comprehensive listing of the world's coal terminals, in a total of 50 countries including information on throughput, facilities, storage capacity, and vessel size limitation.

  2. Retrospective study on prognostic importance of serum procalcitonin and amino-terminal pro-brain natriuretic peptide levels as compared to Acute Physiology and Chronic Health Evaluation IV Score on Intensive Care Unit admission, in a mixed Intensive Care Unit population

    Science.gov (United States)

    Mehta, Chitra; Dara, Babita; Mehta, Yatin; Tariq, Ali M.; Joby, George V.; Singh, Manish K.

    2016-01-01

    Background: Timely decision making in Intensive Care Unit (ICU) is very essential to improve the outcome of critically sick patients. Conventional scores like Acute Physiology and Chronic Health Evaluation (APACHE IV) are quite cumbersome with calculations and take minimum 24 hours. Procalcitonin has shown to have prognostic value in ICU/Emergency department (ED) in disease states like pneumonia, sepsis etc. NTproBNP has demonstrated excellent diagnostic and prognostic importance in cardiac diseases. It has also been found elevated in non-cardiac diseases. We chose to study the prognostic utility of these markers on ICU admission. Settings and Design: Retrospective observational study. Materials and Methods: A Retrospective analysis of 100 eligible patients was done who had undergone PCT and NTproBNP measurements on ICU admission. Their correlations with all cause mortality, length of hospital stay, need for ventilator support, need for vasopressors were performed. Results: Among 100 randomly selected ICU patients, 28 were non-survivors. NTproBNP values on admission significantly correlated with all cause mortality (P = 0.036, AUC = 0.643) and morbidity (P = 0.000, AUC = 0.763), comparable to that of APACHE-IV score. PCT values on admission did not show significant association with mortality, but correlated well with morbidity and prolonged hospital length of stay (AUC = 0.616, P = 0.045). Conclusion: The current study demonstrated a good predictive value of NTproBNP, in terms of mortality and morbidity comparable to that of APACHE-IV score. Procalcitonin, however, was found to have doubtful prognostic importance. These findings need to be confirmed in a prospective larger study. PMID:27052066

  3. Native pyroglutamation of huwentoxin-IV: a post-translational modification that increases the trapping ability to the sodium channel.

    Directory of Open Access Journals (Sweden)

    Mingqiang Rong

    Full Text Available Huwentoxin-IV (HWTX-IV, a tetrodotoxin-sensitive (TTX-s sodium channel antagonist, is found in the venom of the Chinese spider Ornithoctonus huwena. A naturally modified HWTX-IV (mHWTX-IV, having a molecular mass 18 Da lower than HWTX-IV, has also been isolated from the venom of the same spider. By a combination of enzymatic fragmentation and MS/MS de novo sequencing, mHWTX-IV has been shown to have the same amino acid sequence as that of HWTX-IV, except that the N-terminal glutamic acid replaced by pyroglutamic acid. mHWTX-IV inhibited tetrodotoxin-sensitive voltage-gated sodium channels of dorsal root ganglion neurons with an IC50 nearly equal to native HWTX-IV. mHWTX-IV showed the same activation and inactivation kinetics seen for native HWTX-IV. In contrast with HWTX-IV, which dissociates at moderate voltage depolarization voltages (+50 mV, 180000 ms, mHWTX-IV inhibition of TTX-sensitive sodium channels is not reversed by strong depolarization voltages (+200 mV, 500 ms. Recovery of Nav1.7current was voltage-dependent and was induced by extreme depolarization in the presence of HWTX-IV, but no obvious current was elicited after application of mHWTX-IV. Our data indicate that the N-terminal modification of HWTX-IV gives the peptide toxin a greater ability to trap the voltage sensor in the sodium channel. Loss of a negative charge, caused by cyclization at the N-terminus, is a possible reason why the modified toxin binds much stronger. To our knowledge, this is the first report of a pyroglutamic acid residue in a spider toxin; this modification seems to increase the trapping ability of the voltage sensor in the sodium channel.

  4. Aqueous complexation of thorium(IV), uranium(IV), neptunium(IV), plutonium(III/IV), and cerium(III/IV) with DTPA.

    Science.gov (United States)

    Brown, M Alex; Paulenova, Alena; Gelis, Artem V

    2012-07-16

    Aqueous complexation of Th(IV), U(IV), Np(IV), Pu(III/IV), and Ce(III/IV) with DTPA was studied by potentiometry, absorption spectrophotometry, and cyclic voltammetry at 1 M ionic strength and 25 °C. The stability constants for the 1:1 complex of each trivalent and tetravalent metal were calculated. From the potentiometric data, we report stability constant values for Ce(III)DTPA, Ce(III)HDTPA, and Th(IV)DTPA of log β(101) = 20.01 ± 0.02, log β(111) = 22.0 ± 0.2, and log β(101) = 29.6 ± 1, respectively. From the absorption spectrophotometry data, we report stability constant values for U(IV)DTPA, Np(IV)DTPA, and Pu(IV)DTPA of log β(101) = 31.8 ± 0.1, 32.3 ± 0.1, and 33.67 ± 0.02, respectively. From the cyclic voltammetry data, we report stability constant values for Ce(IV) and Pu(III) of log β(101) = 34.04 ± 0.04 and 20.58 ± 0.04, respectively. The values obtained in this work are compared and discussed with respect to the ionic radius of each cationic metal.

  5. The Modern RPG IV Language

    CERN Document Server

    Cozzi, Robert

    2006-01-01

    This updated, classic work on the RPG language covers all the new functions and features that have been added since 2003, including new op codes and built-in functions, new chapters on free-format RPG IV and Web programming interfaces, information on implementing XML within RPG IV, and expanded information on procedures. This reference guide takes both novice and experienced RPG IV programmers through the language, from its foundation to its most advanced techniques. More than 100 charts and tables, as well as 350 real-life code samples of functions and operations are included, showing readers

  6. The Goodpasture autoantigen. Structural delineation of two immunologically privileged epitopes on alpha3(IV) chain of type IV collagen.

    Science.gov (United States)

    Kalluri, R; Sun, M J; Hudson, B G; Neilson, E G

    1996-04-12

    The family of type IV collagen comprises six chains numbered alpha1 through alpha6. The alpha3(IV) NC1 domain is the primary target antigen for autoantibodies from patients with anti-basement membrane disease and Goodpasture syndrome. Earlier peptide studies suggested that the last 36 amino acids of the alpha3 NC1 domain probably contains one recognition site for Goodpasture autoantibodies, and an algorithm analysis of secondary structure from a later study predicted a second possible upstream epitope near the triple helix junction. We have used several analytic approaches to evaluate the likelihood of two immunologic epitopes for the Goodpasture antigen. In our first set of studies, peptide antibodies directed against these two putative regions co-inhibited Goodpasture autoantibodies binding to denatured human alpha3(IV) NC1 monomer by nearly 80%, with the helix-junction region of the alpha3 NC1 domain contributing 26% of the binding sites and the C-terminal region contributing the remaining 50%. Second, both of these candidate regions are normally sequestered within the associated alpha3(IV) NC1 hexamer but become more visible for binding by anti-peptide antibodies upon their dissociation, a property that is shared by the Goodpasture autoantibodies. Third, segment deletions of recombinant alpha3 NC1 domain further confirmed the presence of two serologic binding sites. Finally, we looked more closely at the C-terminal binding region of the alpha3(IV) NC1 domain. Since the lysines in that region have been previously advanced as possible contact sites, we created several substitutions within the C-terminal epitope of the alpha3 NC1 domain. Substitution of lysines to alanines revealed lysines 219 and 229 as essential for antibody binding to this distal site; no lysines were present in the NC1 part of the helix-NC1 junction region. Substitutions involving arginine and cysteines to alanines in the same C-terminal region did not produce significant reductions in

  7. Documents from malicious terminals

    Science.gov (United States)

    Berta, Istvan Z.; Vajda, Istvan

    2003-04-01

    The user wishes to communicate with a remote partner over an insecure network. Since the user is a human being, a terminal is needed for communication. Cryptographic algorithms running on the terminal may provide authenticity for the user's messages. In this paper the problem of sending authentic messages from insecure or untrusted terminals is analyzed. In this case attackers are able to gain total control over the terminal, so the user must consider the terminal a potential attacker. Smart cards are often considered the ultimate tool for secure messaging from untrusted terminals. However, their lack of user interface enables man-in-the middle attack from the terminal. The authors assume, that user is a human being with limited memory and computational power, and also makes mistakes in his calculations. They demnostrate, that only exceptional useres are able to authenticate messages without a trusted device. Several biometric media encapsulate the content of the message and the identity of the sender, such as speech, video and handwriting. The authors suggest, that such media is far more difficult to counterfeit than plaintext. Thus, the user must rely on his other resources, like biometric ones. In the protocol proposed by the authors, the user sends messages in a biometric format, strengthened by simple algorithmic authenticators. The smart card functions as a secure time gate ensuring, that the attacker has extremely little time to counterfeit both the biometric and the algorithmic protection on the message. The authors claim, that with the proper calibration of the biometric method and the time gate of the smart card, their protocol is strong enough for practical use.

  8. Local Termination: theory and practice

    CERN Document Server

    Endrullis, Joerg; Waldmann, Johannes

    2010-01-01

    The characterisation of termination using well-founded monotone algebras has been a milestone on the way to automated termination techniques, of which we have seen an extensive development over the past years. Both the semantic characterisation and most known termination methods are concerned with global termination, uniformly of all the terms of a term rewriting system (TRS). In this paper we consider local termination, of specific sets of terms within a given TRS. The principal goal of this paper is generalising the semantic characterisation of global termination to local termination. This is made possible by admitting the well-founded monotone algebras to be partial. We also extend our approach to local relative termination. The interest in local termination naturally arises in program verification, where one is probably interested only in sensible inputs, or just wants to characterise the set of inputs for which a program terminates. Local termination will be also be of interest when dealing with a specif...

  9. Genetics Home Reference: mucopolysaccharidosis type IV

    Science.gov (United States)

    ... Mucopolysaccharidosis type IV (MPS IV), also known as Morquio syndrome, is a progressive condition that mainly affects ... Management Genetic Testing (3 links) Genetic Testing Registry: Morquio syndrome Genetic Testing Registry: Mucopolysaccharidosis, MPS-IV-A ...

  10. La cuadratura del plato

    Directory of Open Access Journals (Sweden)

    Ángeles Mora

    2012-06-01

    Full Text Available Una de las cosas que el Jurado del X Premio de Poesía Vicente Núñez destacó de este libro fue “su exquisito tratamiento del lenguaje”. Y desde luego lo es, es exquisito su tratamiento del lenguaje pero no porque utilice un lenguaje exquisito o excelso sino porque sabe arrancarle al lenguaje de todos los días, a las palabras sencillas, toda la carga poética de emoción e iluminación que llevan dentro. Mónica Doña nos dice que en su libro ha querido huir de un lirismo que muchas veces resulta falso, hueco, y nos habla de que lo que ha querido hacer es “épica cotidiana”, sin héroes, porque por su libro, como por la vida nuestra de todos los días, lo que circulan son seres que sobreviven como pueden en un mundo adverso.

  11. La cuadratura del plato

    OpenAIRE

    Ángeles Mora

    2012-01-01

    Una de las cosas que el Jurado del X Premio de Poesía Vicente Núñez destacó de este libro fue “su exquisito tratamiento del lenguaje”. Y desde luego lo es, es exquisito su tratamiento del lenguaje pero no porque utilice un lenguaje exquisito o excelso sino porque sabe arrancarle al lenguaje de todos los días, a las palabras sencillas, toda la carga poética de emoción e iluminación que llevan dentro. Mónica Doña nos dice que en su libro ha querido huir de un lirismo que muchas veces resulta fa...

  12. A display model for the TOU of PLATO: just a cool toy or a benchmark of opportunities?

    Science.gov (United States)

    Dima, M.; Greggio, D.; Bergomi, M.; Biondi, F.; Farinato, J.; Farisato, G.; Magrin, D.; Lessio, L.; Marafatto, L.; Munari, M.; Pagano, I.; Ragazzoni, R.; Viotto, V.; Piazza, D.

    2016-07-01

    We produced a "toy-model" of one Telescope Optical Unit of PLATO, the Medium sized mission selected by ESA to fly in 2024. This is a six lenses dioptric very wide field camera with a window in front to take care of radiation impact on the first lens whose optical glass cannot be replaced with a radiation hardened one. The main aim of this project is just to produce a "cool" model for display purposes, in which one can "explore" the details of the inside through some openings in the tube, in order to visually inspect some of the fine details of the opto-mechanics. While its didactic and advertising role is out of doubt, during its construction we realized that some interesting outcome can be of some relevance for the project itself and that some findings could be useful, in order to assess the ability of producing with the same technology some (of course of much more modest quality) optical systems. In this context, we immediately dropped the option of producing the lenses with opaque material painted with a color resembling a refractive material (like blue for instance) and decided to actually produce them with transparent plastic. Furthermore the surfaces are then finely polished in order to give them basic optical properties. Such an optical system has only very coarsely the converging properties of the original nominal design for a number of reasons: the refractive indexes are not the nominal ones, the quality of the surfaces and their nominal values are only roughly, within a few percent, the targeted one, and the way the surfaces are built up makes them prone to some diffraction effects. However, the bulk of the lens and the surface roughness will give a large magnification of the scattering effects that will be experienced, at a much lower level, on the actual flight model. We investigated through propagation of a laser beam and by digital camera the main stray light modes that this toymodel offers. In other words, the model amplifies, to a large extent, the

  13. Interaction between Escherichia coli DNA polymerase IV and single-stranded DNA-binding protein is required for DNA synthesis on SSB-coated DNA.

    Science.gov (United States)

    Furukohri, Asako; Nishikawa, Yoshito; Akiyama, Masahiro Tatsumi; Maki, Hisaji

    2012-07-01

    DNA polymerase IV (Pol IV) is one of three translesion polymerases in Escherichia coli. A mass spectrometry study revealed that single-stranded DNA-binding protein (SSB) in lysates prepared from exponentially-growing cells has a strong affinity for column-immobilized Pol IV. We found that purified SSB binds directly to Pol IV in a pull-down assay, whereas SSBΔC8, a mutant protein lacking the C-terminal tail, failed to interact with Pol IV. These results show that the interaction between Pol IV and SSB is mediated by the C-terminal tail of SSB. When polymerase activity was tested on an SSBΔC8-coated template, we observed a strong inhibition of Pol IV activity. Competition experiments using a synthetic peptide containing the amino acid sequence of SSB tail revealed that the chain-elongating capacity of Pol IV was greatly impaired when the interaction between Pol IV and SSB tail was inhibited. These results demonstrate that Pol IV requires the interaction with the C-terminal tail of SSB to replicate DNA efficiently when the template ssDNA is covered with SSB. We speculate that at the primer/template junction, Pol IV interacts with the tail of the nearest SSB tetramer on the template, and that this interaction allows the polymerase to travel along the template while disassembling SSB.

  14. Modeling Terminal Velocity

    Science.gov (United States)

    Brand, Neal; Quintanilla, John A.

    2013-01-01

    Using a simultaneously falling softball as a stopwatch, the terminal velocity of a whiffle ball can be obtained to surprisingly high accuracy with only common household equipment. This classroom activity engages students in an apparently daunting task that nevertheless is tractable, using a simple model and mathematical techniques at their…

  15. Making Wireless Terminals Simpler

    DEFF Research Database (Denmark)

    Christensen, Søren Skovgaard; Popovski, Petar; De Carvalho, Elisabeth

    2005-01-01

    The exponential growth of user demands and the limitations of 3G systems have brought researchers and industry to propose solutions for the next generation. Among the requirements are higher bit rates and cheaper deployment. In this paper we focus on a terminal complexity problem related to chann...

  16. 苏格拉底、柏拉图、亚里士多德与丑%Socrates,Plato and Aristotle's Views on Ugliness

    Institute of Scientific and Technical Information of China (English)

    区翰子; 李佳

    2014-01-01

    尽管从苏格拉底开始就萌生“丑”这个美学范畴,其在古代一直处于被忽视和非独立的地位。拟通过分析苏格拉底、柏拉图和亚里士多德三位巨匠的“丑”观,揭示“审丑”在萌芽时期的状态。%Despite its first faint showing started from Socrates , Ugliness had constantly been over-looked as a dependent aesthetic category in the ancient time .The following discussion will analyze the views of Socrates ,Plato and Aristotle on the appreciation of ugliness ,thus revealing the state of the appre-ciation of ugliness in its earlier stage .

  17. On Aesthetic Thoughts of Socrates, Plato and Aristotle%古希腊“三贤”美育思想概论

    Institute of Scientific and Technical Information of China (English)

    秦宾; 刘忠伟

    2011-01-01

    Based on analysis of aesthetic thoughts of Socrates, Plato and Aristotle, the famous philosophers in ancient Greek, this paper attempts to use their ideas for reference in guiding the cur- rent teaching practice to better aesthetic education.%通过对古希腊时期三位著名哲学家苏格拉底、柏拉图、亚里土多德美育思想的简要概括和论述,试图从他们对美育思想的主张中提取有益于符合我们现实国情的教育理念,对我们在教学实践中更好地实施美育教育提供可资借鉴的依据。

  18. NPOESS Field Terminal Updates

    Science.gov (United States)

    Heckmann, G.; Route, G.

    2009-12-01

    The National Oceanic and Atmospheric Administration (NOAA), Department of Defense (DoD), and National Aeronautics and Space Administration (NASA) are jointly acquiring the next-generation weather and environmental satellite system; the National Polar-orbiting Operational Environmental Satellite System (NPOESS). NPOESS replaces the current Polar-orbiting Operational Environmental Satellites (POES) managed by NOAA and the Defense Meteorological Satellite Program (DMSP) managed by the DoD. The NPOESS satellites carry a suite of sensors that collect meteorological, oceanographic, climatological, and solar-geophysical observations of the earth, atmosphere, and space. The ground data processing segment for NPOESS is the Interface Data Processing Segment (IDPS), developed by Raytheon Intelligence and Information Systems. The IDPS processes NPOESS satellite data to provide environmental data products (aka, Environmental Data Records or EDRs) to NOAA and DoD processing centers operated by the United States government. The IDPS will process EDRs beginning with the NPOESS Preparatory Project (NPP) and continuing through the lifetime of the NPOESS system. IDPS also provides the software and requirements for the Field Terminal Segment (FTS). NPOESS provides support to deployed field terminals by providing mission data in the Low Rate and High Rate downlinks (LRD/HRD), mission support data needed to generate EDRs and decryption keys needed to decrypt mission data during Selective data Encryption (SDE). Mission support data consists of globally relevant data, geographically constrained data, and two line element sets. NPOESS provides these mission support data via the Internet accessible Mission Support Data Server and HRD/LRD downlinks. This presentation will illustrate and describe the NPOESS capabilities in support of Field Terminal users. This discussion will include the mission support data available to Field Terminal users, content of the direct broadcast HRD and LRD

  19. The Differences between Plato and Aristotle's Educational Philosophy%柏拉图与亚里士多德教育哲学的差异

    Institute of Scientific and Technical Information of China (English)

    刘良华

    2012-01-01

    古典西方教育哲学分为两个阵营:柏拉图以苏格拉底的名义组建他的“理想国”,按照“理论理性”设计他的“政治哲学”和教育方案;柏拉图坚持“哲人王”统治、公产制和道德教育。亚里士多德虽然坚持了哲学对政治的指导,但他看到了哲学对政治的危险,按照“实践理性”的优先性开创了不同于柏拉图的“政治哲学”的“政治科学”以及相关的教育方案。亚里士多德重视轮流制、私有制和法制教育。%The classical philosophy of education is divided into two camps. Plato built his Republic in the name of Socrates and designed the political philosophy and education plan with the theoretical reason. He adhered to the rule of the “philosophy king”, the communist membership system and moral education. Aristotle realized the danger of the philosophy to the politics, although he insisted in the guidance of philosophy to politics. He created the political science and education plan with the practical reason instead of Plato's political philosophy. He valued the political rule, the private ownership, and the legal education.

  20. Confirmatory factor analysis of the WAIS-IV/WMS-IV.

    Science.gov (United States)

    Holdnack, James A; Xiaobin Zhou; Larrabee, Glenn J; Millis, Scott R; Salthouse, Timothy A

    2011-06-01

    The Wechsler Adult Intelligence Scale-fourth edition (WAIS-IV) and the Wechsler Memory Scale-fourth edition (WMS-IV) were co-developed to be used individually or as a combined battery of tests. The independent factor structure of each of the tests has been identified; however, the combined factor structure has yet to be determined. Confirmatory factor analysis was applied to the WAIS-IV/WMS-IV Adult battery (i.e., age 16-69 years) co-norming sample (n = 900) to test 13 measurement models. The results indicated that two models fit the data equally well. One model is a seven-factor solution without a hierarchical general ability factor: Verbal Comprehension, Perceptual Reasoning, Processing Speed, Auditory Working Memory, Visual Working Memory, Auditory Memory, and Visual Memory. The second model is a five-factor model composed of Verbal Comprehension, Perceptual Reasoning, Processing Speed, Working Memory, and Memory with a hierarchical general ability factor. Interpretative implications for each model are discussed.