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Sample records for plato iv system

  1. PLATO IV Accountancy Index.

    Science.gov (United States)

    Pondy, Dorothy, Comp.

    The catalog was compiled to assist instructors in planning community college and university curricula using the 48 computer-assisted accountancy lessons available on PLATO IV (Programmed Logic for Automatic Teaching Operation) for first semester accounting courses. It contains information on lesson access, lists of acceptable abbreviations for…

  2. The PLATO Dome A site-testing observatory: Power generation and control systems

    Science.gov (United States)

    Lawrence, J. S.; Ashley, M. C. B.; Hengst, S.; Luong-van, D. M.; Storey, J. W. V.; Yang, H.; Zhou, X.; Zhu, Z.

    2009-06-01

    The atmospheric conditions above Dome A, a currently unmanned location at the highest point on the Antarctic plateau, are uniquely suited to astronomy. For certain types of astronomy Dome A is likely to be the best location on the planet, and this has motivated the development of the Plateau Observatory (PLATO). PLATO was deployed to Dome A in early 2008. It houses a suite of purpose-built site-testing instruments designed to quantify the benefits of Dome A site for astronomy, and science instruments designed to take advantage of the observing conditions. The PLATO power generation and control system is designed to provide continuous power and heat, and a high-reliability command and communications platform for these instruments. PLATO has run and collected data throughout the winter 2008 season completely unattended. Here we present a detailed description of the power generation, power control, thermal management, instrument interface, and communications systems for PLATO, and an overview of the system performance for 2008.

  3. The PLATO System: A Study in the Diffusion of an Innovation.

    Science.gov (United States)

    Driscoll, Francis D.; Wolf, W. C., Jr.

    This study was designed to ascertain the relationships between the steps of a tool designed to link knowledge production and the needs of knowledge users (the Wolf-Welsh Linkage Methodology or WWLM) with milestones in the evolution of an innovative computer-assisted instructional system called PLATO (Programming Logic for Advanced Teaching…

  4. Plato (power load analysis tool) - a module of west wall monitoring system

    International Nuclear Information System (INIS)

    Ranjan, Sutapa; Travere, Jean-marcel; Moreau, P.

    2015-01-01

    The mandate of the WEST (W Environment for Steady-state Tokamak) project, is to upgrade the medium- sized superconducting Tokamak, Tore Supra in a major scale. One of it's objectives, is to also act as a test-bed for ITER divertor components, to be procured and used in ITER. WEST would be installing actively cooled Tungsten divertor elements, like the ones to be used in ITER. These components would be tested under two experimental scenarios: high power (Ip = 0.8MA, lasting 30s with 15MW injected power) and high fluence (Ip = 0.6 MA, lasting 1000s with 12 MW injected power). Heat load on the divertor target will range from a few MW/m 2 up to 20 MW/m 2 depending on the X point location and the heat flux decay length. The tungsten Plasma Facing Components (PFCs) are less tolerant to overheating than their Carbon counterparts and prevention of their burnout is a major concern. It is in this context that the Wall Monitoring System (WMS) - a software framework aimed at monitoring the health of the Wall components, was conceived. WMS has been divided into three parts: a) a pre-discharge power load analysis tool to check compatibility between plasma scenario and PFC's operational limits in terms of heat flux b) a real-time system during discharge, to take into account all necessary measurements involved in the PFCs protection c) a set of analysis tools that would be used post-discharge, that would access WEST database and compare predicted and experimental results. This paper presents an overview of PLATo - the pre-pulse module of WMS that has been recently developed under IPR-IRFM research collaboration. PLAto has two major components - one that produces heat flux information of the PFCS and the other that produces energy graphs depending on shot profile defined by time variant magnetic equilibrium and injected power profiles. Preliminary results will be presented based on foreseen WEST plasma reference scenarios. (author)

  5. Dosimetric evaluation of PLATO and Oncentra treatment planning systems for High Dose Rate (HDR) brachytherapy gynecological treatments

    Energy Technology Data Exchange (ETDEWEB)

    Singh, Hardev; De La Fuente Herman, Tania; Showalter, Barry; Thompson, Spencer J.; Syzek, Elizabeth J.; Herman, Terence; Ahmad, Salahuddin [Department of Radiation Oncology, Peggy and Charles Stephenson Oklahoma Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104 (United States)

    2012-10-23

    This study compares the dosimetric differences in HDR brachytherapy treatment plans calculated with Nucletron's PLATO and Oncentra MasterPlan treatment planning systems (TPS). Ten patients (1 T1b, 1 T2a, 6 T2b, 2 T4) having cervical carcinoma, median age of 43.5 years (range, 34-79 years) treated with tandem and ring applicator in our institution were selected retrospectively for this study. For both Plato and Oncentra TPS, the same orthogonal films anterior-posterior (AP) and lateral were used to manually draw the prescription and anatomical points using definitions from the Manchester system and recommendations from the ICRU report 38. Data input for PLATO was done using a digitizer and Epson Expression 10000XL scanner was used for Oncentra where the points were selected on the images in the screen. The prescription doses for these patients were 30 Gy to points right A (RA) and left A (LA) delivered in 5 fractions with Ir-192 HDR source. Two arrangements: one dwell position and two dwell positions on the tandem were used for dose calculation. The doses to the patient points right B (RB) and left B (LB), and to the organs at risk (OAR), bladder and rectum for each patient were calculated. The mean dose and the mean percentage difference in dose calculated by the two treatment planning systems were compared. Paired t-tests were used for statistical analysis. No significant differences in mean RB, LB, bladder and rectum doses were found with p-values > 0.14. The mean percent difference of doses in RB, LB, bladder and rectum are found to be less than 2.2%, 1.8%, 1.3% and 2.2%, respectively. Dose calculations based on the two different treatment planning systems were found to be consistent and the treatment plans can be made with either system in our department without any concern.

  6. Finding Ernst Mayr's Plato.

    Science.gov (United States)

    Powers, Jack

    2013-12-01

    Many biologists have accepted Ernst Mayr's claim that evolutionary biology undermined an essentialist or typological view of species that had its roots in Platonic philosophy. However, Mayr has been accused of failing to support with textual evidence his attributions to Plato of these sorts of views about biology. Contemporary work in history and philosophy of biology often seems to take onboard Mayr's account of Plato's view of species. This paper seeks to provide a critical account of putative inconsistencies between an evolutionary view of species and Platonic philosophy with renewed attention to the Platonic texts in light of recent Plato scholarship; I argue that claims that Plato held an essentialist view of species inconsistent with evolutionary biology are inadequately supported by textual evidence. If Mayr's essentialist thesis fails, one might think that the intuition that Platonic philosophy is in tension with Darwinian evolution could nonetheless be accounted for by Plato's apparent privileging of a certain sort of teleological explanation, a thesis that Mayr suggests in his 1959 paper on Louis Agassiz. However, this thesis also faces difficulties. Ernst Mayr's Plato is more likely to be found in the writings of anti-evolutionary 19th century biologists like Mayr's frequent target, Agassiz, than in a cautious reading of the Platonic dialogues themselves. Interlocutors in discussions of the history of biological thought and classificatory methods in biology should be cautious in ascribing views about biology to Plato and using terms like "Platonic essentialism." Copyright © 2013 Elsevier Ltd. All rights reserved.

  7. [Plato psychiatrist, Foucault platonic].

    Science.gov (United States)

    Mathov, Nicolás

    2016-05-01

    This work explores the links between the concepts of "soul", "law" and "word" in Plato's work, in order to highlight the importance and the centrality of the philosophical-therapeutic dimension in the Greek philosopher's thought. In that way, this work pretends to show that "contemporary" problems usually discussed within "Human Sciences" in general, and Psychiatry in particular, should confront their knowledge with Plato's work, mainly due to the profound influence his ideas have had in our Greco-Christian culture. In that sense, and with that objective, this work also explores Michel Foucault's lucid and controversial interpretation of Plato.

  8. PLATO Esperanto Materials.

    Science.gov (United States)

    Sherwood, Judith

    1981-01-01

    A summary is presented of types of Esperanto materials available on PLATO--a general overview section, a picture introduction, lessons that accompany a textbook, vocabulary drills, crossword puzzles, dictation drills, reading practice, and a concentration game. The general overview lesson gives a comprehensive summary of the history and…

  9. The PLATO 2.0 mission

    NARCIS (Netherlands)

    Rauer, H.; et al., [Unknown; Hekker, S.

    2014-01-01

    PLATO 2.0 has recently been selected for ESA’s M3 launch opportunity (2022/24). Providing accurate key planet parameters (radius, mass, density and age) in statistical numbers, it addresses fundamental questions such as: How do planetary systems form and evolve? Are there other systems with planets

  10. From Pericles to Plato

    DEFF Research Database (Denmark)

    Larsen, Øjvind

    2012-01-01

    Plato is normally taken as one of the founders of Western political philosophy, not at least with his Republic. Here, he constructs a hierarchy of forms of governments, beginning with aristocracy at the top as a critical standard for the other forms of governments, and proceeding through timocracy......’ funeral oration is used to show that Pericles presented a democratic political philosophy that can serve as a counterpoint to Plato’s political philosophy in the Republic....

  11. Verification of the calculation program for brachytherapy planning system of high dose rate (PLATO)

    International Nuclear Information System (INIS)

    Almansa, J.; Alaman, C.; Perez-Alija, J.; Herrero, C.; Real, R. del; Ososrio, J. L.

    2011-01-01

    In our treatments are performed brachytherapy high dose rate since 2007. The procedures performed include gynecological intracavitary treatment and interstitial. The treatments are performed with a source of Ir-192 activity between 5 and 10 Ci such that small variations in treatment times can cause damage to the patient. In addition the Royal Decree 1566/1998 on Quality Criteria in radiotherapy establishes the need to verify the monitor units or treatment time in radiotherapy and brachytherapy. All this justifies the existence of a redundant system for brachytherapy dose calculation that can reveal any abnormality is present.

  12. Peers on Socrates and Plato

    Science.gov (United States)

    Mackenzie, Jim

    2014-01-01

    There is more to be said about two of the topics Chris Peers addresses in his article "Freud, Plato and Irigaray: A morpho-logic of teaching and learning" (2012, Educational Philosophy and Theory, 44, 760-774), namely the Socratic method of teaching and Plato's stance with regard to women and feminism. My purpose in this article is…

  13. Plato's patricide in the sophist

    Directory of Open Access Journals (Sweden)

    Deretić Irina J.

    2012-01-01

    Full Text Available In this paper, the author attempts to elucidate validity of Plato's criticism of Parmenides' simplified monistic ontology, as well as his concept of non-being. In contrast to Parmenides, Plato introduces a more complex ontology of the megista gene and redefines Parmenides' concept of non-being as something absolutely different from being. According to Plato, not all things are in the same sense, i. e. they have the different ontological status. Additionally, he redefines Parmenides' concept of absolute non-being as 'difference' or 'otherness.' .

  14. Safety assessment for Generation IV nuclear systems

    International Nuclear Information System (INIS)

    Leahy, T.J.

    2012-01-01

    The Generation IV International Forum (GIF) Risk and Safety Working Group (RSWG) was created to develop an effective approach for the safety of Generation IV advanced nuclear energy systems. Recent RSWG work has focused on the definition of an integrated safety assessment methodology (ISAM) for evaluating the safety of Generation IV systems. ISAM is an integrated 'tool-kit' consisting of 5 analytical techniques that are available and matched to appropriate stages of Generation IV system concept development: 1) qualitative safety features review - QSR, 2) phenomena identification and ranking table - PIRT, 3) objective provision tree - OPT, 4) deterministic and phenomenological analyses - DPA, and 5) probabilistic safety analysis - PSA. The integrated methodology is intended to yield safety-related insights that help actively drive the evolving design throughout the technology development cycle, potentially resulting in enhanced safety, reduced costs, and shortened development time

  15. Phusis and Nomos in Plato

    Directory of Open Access Journals (Sweden)

    Zahra Nouri Sanghdehi

    2017-07-01

    Full Text Available One of the greatest problems in Plato that appears in different forms in his works is the relation of nomos and phusis. This thesis has been in fifth century B.C as the contradiction of phusis and nomos among big thinkers. In this essay, we tried to investigate the relation of phusis and nomos in Plato’s thoughts according to current theories of the contradiction of these in dialogues Gorgias, Republic and Protagoras. Plato tries to minimize consequences of belief to contradiction of phusis and nomos in social and political life by assertion large scale relation between phusis and nomos. Plato depicts the ultimate solution of this problem in Law. There he accounts nomos as raised from phusis that is sub sovereignty of divine. Indeed union of phusis and gods in Plato’s thought is sanction for the identity of phusis and nomos.

  16. Four Educators in Plato's "Theaetetus"

    Science.gov (United States)

    Mintz, Avi I.

    2011-01-01

    Scholars who have taken interest in "Theaetetus'" educational theme argue that Plato contrasts an inferior, even dangerous, sophistic education to a superior, philosophical, Socratic education. I explore the contrasting exhortations, methods, ideals and epistemological foundations of Socratic and Protagorean education and suggest that Socrates'…

  17. PLATO[R] Achieve Now. What Works Clearinghouse Intervention Report

    Science.gov (United States)

    What Works Clearinghouse, 2010

    2010-01-01

    "PLATO[R] Achieve Now" is a software-based curriculum for the elementary and middle school grades. Instructional content is delivered via the PlayStation Portable (PSP[R]) system, allowing students to access learning materials in various settings. Software-based assessments are used to customize individual instruction, allowing students…

  18. Modcomp MAX IV System Processors reference guide

    Energy Technology Data Exchange (ETDEWEB)

    Cummings, J.

    1990-10-01

    A user almost always faces a big problem when having to learn to use a new computer system. The information necessary to use the system is often scattered throughout many different manuals. The user also faces the problem of extracting the information really needed from each manual. Very few computer vendors supply a single Users Guide or even a manual to help the new user locate the necessary manuals. Modcomp is no exception to this, Modcomp MAX IV requires that the user be familiar with the system file usage which adds to the problem. At General Atomics there is an ever increasing need for new users to learn how to use the Modcomp computers. This paper was written to provide a condensed Users Reference Guide'' for Modcomp computer users. This manual should be of value not only to new users but any users that are not Modcomp computer systems experts. This Users Reference Guide'' is intended to provided the basic information for the use of the various Modcomp System Processors necessary to, create, compile, link-edit, and catalog a program. Only the information necessary to provide the user with a basic understanding of the Systems Processors is included. This document provides enough information for the majority of programmers to use the Modcomp computers without having to refer to any other manuals. A lot of emphasis has been placed on the file description and usage for each of the System Processors. This allows the user to understand how Modcomp MAX IV does things rather than just learning the system commands.

  19. Future development of the PLATO Observatory for Antarctic science

    Science.gov (United States)

    Ashley, Michael C. B.; Bonner, Colin S.; Everett, Jon R.; Lawrence, Jon S.; Luong-Van, Daniel; McDaid, Scott; McLaren, Campbell; Storey, John W. V.

    2010-07-01

    PLATO is a self-contained robotic observatory built into two 10-foot shipping containers. It has been successfully deployed at Dome A on the Antarctic plateau since January 2008, and has accumulated over 730 days of uptime at the time of writing. PLATO provides 0.5{1kW of continuous electrical power for a year from diesel engines running on Jet-A1, supplemented during the summertime with solar panels. One of the 10-foot shipping containers houses the power system and fuel, the other provides a warm environment for instruments. Two Iridium satellite modems allow 45 MB/day of data to be transferred across the internet. Future enhancements to PLATO, currently in development, include a more modular design, using lithium iron-phosphate batteries, higher power output, and a light-weight low-power version for eld deployment from a Twin Otter aircraft. Technologies used in PLATO include a CAN (Controller Area Network) bus, high-reliability PC/104 com- puters, ultracapacitors for starting the engines, and fault-tolerant redundant design.

  20. Prospects for detecting decreasing exoplanet frequency with main-sequence age using PLATO

    Science.gov (United States)

    Veras, D.; Brown, D. J. A.; Mustill, A. J.; Pollacco, D.

    2017-09-01

    The space mission PLATO will usher in a new era of exoplanetary science by expanding our current inventory of transiting systems and constraining host star ages, which are currently highly uncertain. This capability might allow PLATO to detect changes in planetary system architecture with time, particularly because planetary scattering due to Lagrange instability may be triggered long after the system was formed. Here, we utilize previously published instability time-scale prescriptions to determine PLATO's capability to detect a trend of decreasing planet frequency with age for systems with equal- mass planets. For two-planet systems, our results demonstrate that PLATO may detect a trend for planet masses which are at least as massive as super-Earths. For systems with three or more planets, we link their initial compactness to potentially detectable frequency trends in order to aid future investigations when these populations will be better characterized.

  1. Development of generation IV nuclear energy systems

    International Nuclear Information System (INIS)

    Matsui, Kazuaki; Oka, Yoshiaki; Ogawa, Masuro; Ichimiya, Masakazu; Noda, Hiroshi

    2003-01-01

    The fifth 'Generation IV International Forum (GIF), Policy Group Meetings' was held at the Zen-Nikku Hotel in Tokyo, on September 19-20, 2002, under participations of Abraham, Secretary of DOE in U.S.A., Columbani, Secretary of CEA in France, Fujiie, Chairman of CAE in Japan, Kano, Parliamental Minister of MIS in Japan, and so on. Ten nations entering GIF (Argentina, Brazil, Canada, France, Japan, Korea, South Africa, Switzerland, U.K., and U.S.A.) selected six next generation nuclear energy concepts for objects of international cooperative research and development aiming at its practice by 2030. These concepts applicable to not only power generation, but also hydrogen production, sea water purification, and so on, are sodium liquid metal cooled reactor (Japan), high temperature gas cooled reactor (France), Super-critical pressure water cooled reactor (SCWR: Canada), Lead metal cooled reactor (Switzerland), Gas cooled fast reactor (U.S.A.), and molten salts reactor. On the generation IV nuclear reactor systems aiming to further upgrade their sustainability, safety, economical efficiency, and nuclear non proliferation, the 'Plans on Technical Development' (Road-map) to decide priority of their R and Ds has been cooperatively discussed under frameworks of international research cooperation by the GIF members nations. Here were shared descriptions on nuclear fuel cycle as a remise of technical evaluation and adopted concepts by Japanese participants contributing to making up the Road-map. (G.K.)

  2. Relations as Plural-Predications in Plato

    OpenAIRE

    Scaltsas, Theodore

    2013-01-01

    Plato was the first philosopher to discover the metaphysical phenomenon of plural-subjects and plural-predication; e.g. you and I are two, but neither you, nor I are two. I argue that Plato devised an ontology for plural-predication through his Theory of Forms, namely, plural-partaking in a Form. Furthermore, I argue that Plato used plural-partaking to offer an ontology of related individuals without reifying relations. My contention is that Plato’s theory of plural-relatives has evaded detec...

  3. Verification of the calculation program for brachytherapy planning system of high dose rate (PLATO); Programa de verificacion del calculo para un sistema de planificacion de braquiterapia de alta tasa de dosis (PLATO)

    Energy Technology Data Exchange (ETDEWEB)

    Almansa, J.; Alaman, C.; Perez-Alija, J.; Herrero, C.; Real, R. del; Ososrio, J. L.

    2011-07-01

    In our treatments are performed brachytherapy high dose rate since 2007. The procedures performed include gynecological intracavitary treatment and interstitial. The treatments are performed with a source of Ir-192 activity between 5 and 10 Ci such that small variations in treatment times can cause damage to the patient. In addition the Royal Decree 1566/1998 on Quality Criteria in radiotherapy establishes the need to verify the monitor units or treatment time in radiotherapy and brachytherapy. All this justifies the existence of a redundant system for brachytherapy dose calculation that can reveal any abnormality is present.

  4. An Integrated Safety Assessment Methodology for Generation IV Nuclear Systems

    International Nuclear Information System (INIS)

    Leahy, Timothy J.

    2010-01-01

    The Generation IV International Forum (GIF) Risk and Safety Working Group (RSWG) was created to develop an effective approach for the safety of Generation IV advanced nuclear energy systems. Early work of the RSWG focused on defining a safety philosophy founded on lessons learned from current and prior generations of nuclear technologies, and on identifying technology characteristics that may help achieve Generation IV safety goals. More recent RSWG work has focused on the definition of an integrated safety assessment methodology for evaluating the safety of Generation IV systems. The methodology, tentatively called ISAM, is an integrated 'toolkit' consisting of analytical techniques that are available and matched to appropriate stages of Generation IV system concept development. The integrated methodology is intended to yield safety-related insights that help actively drive the evolving design throughout the technology development cycle, potentially resulting in enhanced safety, reduced costs, and shortened development time.

  5. The Method of Hypothesis in Plato's Philosophy

    Directory of Open Access Journals (Sweden)

    Malihe Aboie Mehrizi

    2016-09-01

    Full Text Available The article deals with the examination of method of hypothesis in Plato's philosophy. This method, respectively, will be examined in three dialogues of Meno, Phaedon and Republic in which it is explicitly indicated. It will be shown the process of change of Plato’s attitude towards the position and usage of the method of hypothesis in his realm of philosophy. In Meno, considering the geometry, Plato attempts to introduce a method that can be used in the realm of philosophy. But, ultimately in Republic, Plato’s special attention to the method and its importance in the philosophical investigations, leads him to revise it. Here, finally Plato introduces the particular method of philosophy, i.e., the dialectic

  6. Plato's Anti-Kohlbergian Program for Moral Education

    Science.gov (United States)

    Jonas, Mark E.

    2016-01-01

    Following Lawrence Kohlberg it has been commonplace to regard Plato's moral theory as "intellectualist", where Plato supposedly believes that becoming virtuous requires nothing other than "philosophical knowledge or intuition of the ideal form of the good". This is a radical misunderstanding of Plato's educational programme,…

  7. FORMATION OF ANTIQUE RHETORIC: CHRONOLOGY OF RHETORICAL METHODS AND STYLES (PLATO, ARISTOTLE

    Directory of Open Access Journals (Sweden)

    Irina A. Pantelyeyeva

    2013-09-01

    Full Text Available Purpose of the article: to analyze the basic points of philosophical concepts of rhetoric of Plato and Aristotle, to prove that from Plato the rhetoric in the true sense starts being approved, and Aristotle is an ancestor of real theory of speech of the new genre, the new form, the new purposes and tasks of the description of verbal art. Problem statement: development of the ancient principles of rhetorical style’s creating is reached by efforts of outstanding speakers, each of them were differed not only by the ideological sympathies or antipathies, but also by nature of works, the concepts put in their basis. Two Ancient Greek philosophers: Plato and Aristotle are considered as founders of ancient rhetorical science. Methodology. Author has used system method, methods of content and comparative analysis. Scientific novelty is displayed in the received results from the comparative analysis of two concepts of public speech of Plato and Aristotle from a position of philosophical justification of rhetoric’s rules with orientation on ancient "popular" declamation practices. Practical value of article consists in development of insufficiently studied object "Antique declamation discourse" where Plato and Aristotle's two central rhetorical concepts appear as the intermediate stage in development of a declamation discourse of Ancient Greece and, subsequently, and Ancient Rome. Conclusions. The conclusions can be given by the following facts: from Plato the rhetoric in the true sense is approved: true rhetorical art isn’t based only on argument technique, the true rhethor appears as the philosopher. Plato raises the problem of an ambiguity of two opposite rhetorics presented in "Gorgias" and "Phaedrus ". Rhetoric as scientific discipline, as the present theory of speech is first considered by Aristotle. The rhetoric is presented as the science "about speech and about thoughts", about the relation of thinking to the word.

  8. Plato's problem an introduction to mathematical platonism

    CERN Document Server

    Panza, M

    2013-01-01

    What is mathematics about? And how can we have access to the reality it is supposed to describe? The book tells the story of this problem, first raised by Plato, through the views of Aristotle, Proclus, Kant, Frege, Gödel, Benacerraf, up to the most recent debate on mathematical platonism.

  9. Quoting Plato in Porphyrius' Cuestiones homericas

    Directory of Open Access Journals (Sweden)

    Lucía Rodríguez‑Noriega Guillén

    2016-08-01

    Full Text Available This paper studies the quotations of Plato in Porphyry’s Homeric Questions,including their typology (literal quotation, allusion, paraphrase, etc., their beingor not direct citations, their function in the work, and their possible parallels inother authors.

  10. The generation IV nuclear reactor systems - Energy of future

    International Nuclear Information System (INIS)

    Ohai, Dumitru; Jianu, Adrian

    2006-01-01

    Ten nations joined within the Generation IV International Forum (GIF), agreeing on a framework for international cooperation in research. Their goal is to develop future-generation nuclear energy systems that can be licensed, constructed, and operated in an economically competitive way while addressing the issues of safety, proliferation, and other public perception concerns. The objective is for the Gen IV systems to be available for deployment by 2030. Using more than 100 nuclear experts from its 10 member nations, the GIF has developed a Gen IV Technology Roadmap to guide the research and development of the world's most advanced, efficient and safe nuclear power systems. The Gen IV Technology Roadmap calls for extensive research and development of six different potential future reactor systems. These include water-cooled, gas-cooled, liquid metal-cooled and nonclassical systems. One or more of these reactor systems will provide the best combination of safety, reliability, efficiency and proliferation resistance at a competitive cost. The main goals for the Gen IV Nuclear Energy Systems are: - Provide sustainable energy generation that meets clean air objectives and promotes long-term availability of systems and effective fuel use for worldwide energy production; - Minimize and manage their nuclear waste and noticeably reduce the long-term stewardship burden in the future, improving the protection of public health and the environment; - Increase the assurance that these reactors are very unattractive and the least desirable route for diversion or theft of weapons-usable materials, and provide increased protection against acts of terrorism; - Have a clear life-cycle cost advantage over other energy sources; - Have a level of financial risk comparable to other energy projects; - Excel in safety and reliability; - Have a low likelihood and degree of reactor core damage. (authors)

  11. Socrates the Pythagorean: an Invention of Plato?

    Directory of Open Access Journals (Sweden)

    Yury Shichalin

    2012-06-01

    Full Text Available This article discusses the image of Socrates as found in the Works of Plato and Aristophanes. The author discovers Pythagorean traits in the image of Socrates as portrayed by these two ancient authors. The author also discusses the Pythagoreans and their role in the creation of stable schools of Philosophy. He likewise shows that the sophists were not the only ones contributing to the creation of centres of education and learning in the ancient world

  12. Pemikiran Epistemologi Barat: dari Plato Sampai Gonseth

    OpenAIRE

    Nunu Burhanuddin

    2015-01-01

    This paper riviewing the Western epistemology thought. The theme focuses on Plato to Gonseth. The Epistemology that referred in this article, is to think about "how humans acquire knowledge?". From this then appear four types of sect modern western epistemology thought, namely: sect of empiricism, rationalism sect, kantinian sect, sect of positivism. Furthermore, the social positivism sciences developed by Comte leaves serious problems associated with the loss of the role of the subject. This...

  13. Ancient Doctrines of Passions: Plato and Aristotle

    Directory of Open Access Journals (Sweden)

    Iskra-Paczkowska Agnieszka

    2016-09-01

    Full Text Available The subject of this essay is a discussion of the doctrines of emotions of Plato and Aristotle. According to both them it is impossible to oust the passions from the good, i.e. happy life. On the contrary, emotions are an important component of human excellence. We investigate this question with reference to Plato’s doctrine of the soul and his concept of a perfect life, and Aristotle’s ethics, poetics and rhetoric.

  14. Evaluating PLATO: postgraduate teaching and learning online.

    Science.gov (United States)

    Brown, Menna; Bullock, Alison

    2014-02-01

      The use of the Internet as a teaching medium has increased rapidly over the last decade. PLATO (postgraduate learning and teaching online) was launched in 2008 by the e-learning unit (ELU) of Wales Deanery. Located within Learning@NHSWales, a Moodle virtual learning environment (VLE), it hosts a wide range of freely available courses and resources tailored to support the education, training and continuing professional development (CPD) needs of health care professionals working across the National Health Service (NHS) Wales. The evaluation aimed to identify the costs and benefits of PLATO, report its value as attributed by users, identify potential cost savings and make recommendations.   Five courses (case studies) were selected, representing the range of available e-learning resources: e-induction; fetal heart monitoring; cervical screening; GP prospective trainers; and tools for trainers. Mixed methods were used: one-to-one qualitative interviews, focus group discussions and surveys explored user views, and identified individual and organisational value.   Qualitative findings identified six key areas of value for users: ELU support and guidance; avoidance of duplication and standardisation; central reference; local control; flexibility for learners; and specific features. Survey results (n=72) indicated 72 per cent of consultants reported that PLATO was easy to access and user friendly. E-learning was rated as 'very/important' for CPD by 79 per cent of respondents. Key challenges were: access, navigation, user concerns, awareness and support.   PLATO supports education and helps deliver UK General Medical Council standards. Future plans should address the suggested recommendations to realise cost savings for NHS Wales and the Wales Deanery. The findings have wider applicability to others developing or using VLEs. © 2014 John Wiley & Sons Ltd.

  15. Description of the IV + V System Software Package.

    Science.gov (United States)

    Microcomputers for Information Management: An International Journal for Library and Information Services, 1984

    1984-01-01

    Describes the IV + V System, a software package designed by the Institut fur Maschinelle Dokumentation for the United Nations General Information Programme and UNISIST to support automation of local information and documentation services. Principle program features and functions outlined include input/output, databank, text image, output, and…

  16. JRC-IE's research of safety of Gen IV systems

    International Nuclear Information System (INIS)

    Tsige-Tamirat, H.; Ranguelova, V.; Feutterer, M.; Ammirabile, L.; Carlsson, J.; D'Agata, E.; Laurie, M.; Magallon, D.

    2010-01-01

    The Institute for Energy (IE), one of the seven scientific Institutes of the Joint Research Centre (JRC) of the European Commission, has the mission to provide scientific and technical support for the conception, development, implementation and monitoring of community policies related to energy. To accomplish its mission, IE performs research in the areas of renewable energies, safety and sustainability of nuclear energy for current and future reactor systems, energy technic/economic assessment, and security of energy supply. The Generation IV International Forum (GIF) is a cooperative international endeavour organized to carry out R and D needed to establish the feasibility and performance capabilities of the next generation nuclear energy systems and support the progress towards their realization. The EU, represented by EURATOM and with the JRC as implementing agent, is working together with other GIF partners to perform pre-competitive R and D on key technologies to be implemented in future nuclear systems. IE is engaged in experimental research, simulation and modeling, scientific, feasibility and engineering studies on innovative nuclear reactor systems needed to support the EURATOM contribution to GEN IV initiative, in particular in assessment of innovative fuels and materials, development of new reactor core concepts and safety solutions and knowledge management and preservation. IE's research activities on Generation IV reactor systems are focused on the assessment of the potential of such systems to meet long term EU energy needs with respect to economical advantages, enhanced safety, sustainability, and proliferation resistance. IE participates in international collaborations and has bilateral research cooperation both with European and non-European partners. This paper gives an overview of IE's current research activities on the Gen IV reactor systems related to safety. (authors)

  17. Policy-induced market introduction of Generation IV reactor systems

    International Nuclear Information System (INIS)

    Heek, Aliki Irina van; Roelofs, Ferry

    2011-01-01

    Almost 10 years ago the U.S. Department of Energy (DOE) started the Generation IV Initiative (GenIV) with 9 other national governments with a positive ground attitude towards nuclear energy. Some of these Generation IV systems, like the fast reactors, are nearing the demonstration stage. The question on how their market introduction will be implemented becomes increasingly urgent. One main topic for future reactor technologies is the treatment of radioactive waste products. Technological solutions to this issue are being developed. One possible process is the transformation of long-living radioactive nuclides into short living ones; a process known as transmutation, which can be done in a nuclear reactor only. Various Generation IV reactor concepts are suitable for this process, and of these systems most experience has been gained with the sodium-cooled fast reactor (SFR). However, both these first generation SFR plants and their Generation IV successors are designed as electricity generating plants, and therefore supposed to be commercially viable in the electricity markets. Various studies indicate that the generation costs of a combined LWR-(S)FR nuclear generating park (LWR: light water reactor) will be higher than that of an LWR-only park. To investigate the effects of the deployment of the different reactors and fuel cycles on the waste produced, resources used and costs incurred as a function of time, a dynamic fuel cycle assessment is performed. This study will focus on the waste impact of the introduction of a fraction of fast reactors in the European nuclear reactor park with a cost increase as described in the previous paragraph. The nuclear fuel cycle scenario code DANESS is used for this, as well as the nuclear park model of the EU-27 used for the previous study. (orig.)

  18. Pemikiran Epistemologi Barat: dari Plato Sampai Gonseth

    Directory of Open Access Journals (Sweden)

    Nunu Burhanuddin

    2015-06-01

    Full Text Available This paper riviewing the Western epistemology thought. The theme focuses on Plato to Gonseth. The Epistemology that referred in this article, is to think about "how humans acquire knowledge?". From this then appear four types of sect modern western epistemology thought, namely: sect of empiricism, rationalism sect, kantinian sect, sect of positivism. Furthermore, the social positivism sciences developed by Comte leaves serious problems associated with the loss of the role of the subject. This problem being the background of epistemology philosophy appears that by Emund Husserl developed through the phenomenology, Habermas through hermeneutics, and Ferdinand Gonseth through critical theory.

  19. Plato's ghost the modernist transformation of mathematics

    CERN Document Server

    Gray, Jeremy

    2008-01-01

    Plato's Ghost is the first book to examine the development of mathematics from 1880 to 1920 as a modernist transformation similar to those in art, literature, and music. Jeremy Gray traces the growth of mathematical modernism from its roots in problem solving and theory to its interactions with physics, philosophy, theology, psychology, and ideas about real and artificial languages. He shows how mathematics was popularized, and explains how mathematical modernism not only gave expression to the work of mathematicians and the professional image they sought to create for themselves, but how modernism also introduced deeper and ultimately unanswerable questions

  20. Plato the Pederast: Rhetoric and Cultural Procreation in the Dialogues.

    Science.gov (United States)

    Ervin, Elizabeth

    1993-01-01

    Examines Plato's Dialogues by reading them through two cultural lenses: the role of eros in classical Greece and its analogous relationship to language and rhetoric; and the educational function of eros within the ancient institution of pederasty. Shows how the cultural values of ancient Greece manifested themselves in Plato's erotic educational…

  1. Plato's Theories of Knowledge and Education: an Examination of the ...

    African Journals Online (AJOL)

    Plato's Theories of Knowledge and Education: an Examination of the Interpretations of Cloete and Agyemang. ... UJAH: Unizik Journal of Arts and Humanities ... views, this article reveals some serious logical and factual errors in Cloete's interpretations, and thereby clarifies Plato's epistemology and theories of education.

  2. Plato and the teaching of entrepreneurship studies as general ...

    African Journals Online (AJOL)

    Secondly to use Plato's model of education to stress the importance of the practical aspect of entrepreneurial studies so as to avoid the old syndrome of breeding certificate Laden, theory filled entrepreneurial studies. For Plato, education should be tailored to suit the learner specialization; that is a carpenter should be taught ...

  3. Plato: from Socrates to Pre-Socratics?

    Directory of Open Access Journals (Sweden)

    YU. SHICHALIN

    2015-04-01

    Full Text Available The traditional view on the chronology of the Corpus Platonicum (CP texts turns out to be anachronistic from several, especially formal and historical, points of view. From the formal point of view all the CP texts can be divided into speeches, framed dialogues and dialogues in dramatic form; there are serious reasons for correlating these groups of dialogues with different chronological periods. Historically, to view Plato’s works as modern philosophical and scholarly literature is incorrect; instead, it would seem expedient to correlate the three groups of dialogues mentioned with their changing audiences for which Plato wrote before the establishment of the Academy, during the first stage of its existence (before the second trip to Sicily and in the later period. The evolution of Plato’s philosophy is to be correlated with the evolution of the school created by him. Lack of attention to these methods can lead to incorrect assumptions concerning Plato’s evolution which found their way, among others, into the book “Plato and the Post-Socratic Dialogue” by Prof. Ch. Kahn where he speaks of a transition from Socratic to Pre-Socratic problems in Plato’s works; the book is critically examined by the author of the present article.

  4. Corrosion of structural materials for Generation IV systems

    International Nuclear Information System (INIS)

    Balbaud-Celerier, F.; Cabet, C.; Courouau, J.L.; Martinelli, L.; Arnoux, P.

    2009-01-01

    The Generation IV International Forum aims at developing future generation nuclear energy systems. Six systems have been selected for further consideration: sodium-cooled fast reactor (SFR), gas-cooled fast reactor (GFR), lead-cooled fast reactor (LFR), molten salt reactor (MSR), supercritical water-cooled reactor (SCWR) and very high temperature reactor (VHTR). CEA, in the frame of a national program, of EC projects and of the GIF, contributes to the structural materials developments and research programs. Particularly, corrosion studies are being performed in the complex environments of the GEN IV systems. As a matter of fact, structural materials encounter very severe conditions regarding corrosion concerns: high temperatures and possibly aggressive chemical environments. Therefore, the multiple environments considered require also a large diversity of materials. On the other hand, the similar levels of working temperatures as well as neutron spectrum imply also similar families of materials for the various systems. In this paper, status of the research performed in CEA on the corrosion behavior of the structural material in the different environments is presented. The materials studied are either metallic materials as austenitic (or Y, La, Ce doped) and ferrito-martensitic steels, Ni base alloys, ODS steels, or ceramics and composites. In all the environments studied, the scientific approach is identical, the objective being in all cases the understanding of the corrosion processes to establish recommendations on the chemistry control of the coolant and to predict the long term behavior of the materials by the development of corrosion models. (author)

  5. A scientific approach to Plato's Atlantis

    Directory of Open Access Journals (Sweden)

    Massimo Rapisarda

    2015-09-01

    Full Text Available The myth of Atlantis is hard to die. This attempt to use scientific evidence to give it the final smash ends up with the doubt that it might not be totally unsubstantiated. The time of the supposed existence of Atlantis (around twelve thousand years ago was, in fact, characterized by technological revolutions, acknowledged by archaeology, and abrupt climate changes, documented by geology. In principle, it cannot therefore be ruled out that some of those dramatic events left a memory, later used by Plato as a basis for its tale. The climate changes involved the majority of the northern hemisphere, thus all the ancient civilizations (Egyptian, Mesopotamian, Indian and Chinese could have preserved reminiscence, but it is clear that the events occurring closer to Greece would have been more accessible to Plato. Among the Mediterranean sites that experienced the cataclysms of the beginning of the Holocene, a good candidate to host a primordial civilization might have been the archipelago then existing in the Strait of Sicily, a natural maritime link between Tunisia and Italy, prized by the presence of an obsidian source at Pantelleria. Eleven thousand five hundred years ago, a sudden sea level rise erased the archipelago, submerging the possible settlements, but Pantelleria obsidian ores are still there and could provide a significant clue. In fact, the potential discovery of artefacts, originating from a source now submerged by the sea level rise, would imply that the collection of the mineral took place when it was still emerged, namely at the time of Atlantis. Even if such discovery would not be sufficient to prove the existence of the mythical island, it would be enough to shake up the timeline of the human occupation in the region.

  6. What Plato and Murdoch Think About Love

    Directory of Open Access Journals (Sweden)

    Shadi Shakouri

    2012-07-01

    Full Text Available There are many interpretations of love and lots of scholars write and talk on love; however, what exactly is the meaning of love? Iris Murdoch’s works are an accumulation of emotional relationships and feelings of love. Her great subject is love, both sexual and non-sexual, and her characters are the portrayal of a small group of people caught up in convoluted ties of love and hate, with Eros ruling over them (Cohen 22. Murdoch was one of the most respected British writers and philosophers of the second half of the twentieth century and, of course, the postwar period. In Murdoch’s novels, love is one of the central themes—marriage, as the institution of love, more often binds than frees. Her characters are mainly ego-centric people who struggle to love and are often overwhelmed by the factor of self-obsession, jealousy, ambition, fascination with suffering and charismatic power. They are absolutely ordinary people with a consuming demand for love, and mental and physical exile. Murdoch was inspired by Plato’s ideas in many ways. Like art, here again Plato’s idea of love is more skeptical than Murdoch’s, whereas Murdoch kept it only as a way to the Good, creation, and happiness. Murdoch and Plato saw love more as a Freudian concept, the Eros, the word that comes from the name of the first Greek god of love. Both the philosophers, Plato and Murdoch, believed that this erotic longing and desires revived by Eros can led to a new direction, a way toward virtue and truth. Her protagonist or marginalized characters are usually tackling it with either vulgarity or the heavenly, which results in creation, art or salvation. Murdoch, as a major moral philosopher, usually grasps the chances to encapsulate her moral visions in her works, and created novels that should be counted as meditations on human love and goodness.

  7. Dose distribution around Ir192 brachytherapy source in non-full scattering conditions: comparison of in-phantom measurements and Nucletron-Oldelft plato system calculations

    International Nuclear Information System (INIS)

    Jastrzembski, Michal; Kabacinska, Renata; Makarewicz, Roman

    1996-01-01

    Introduction: Comparing the values of doses measured in vivo during gynaecological brachytherapy with those computed with the use of Nucletron-Oldelft brachytherapy treatment planning system a high level of uncertainty appears. In case of points located close to the media border this is also due to the lack of scattering in this region. The influence of the lack of scattering on dose distribution has been investigated. Measured data has been compared to those given by Nucletron-Oldelft BPS. Materials and methods: Profiles in a large water phantom (PTW MP3 system) has been measured in directions perpendicular to the long axis of the fixed source at varied water level and at varied source-to-detector distances. Normalization values for the curves has been acquired by absolute dose measurements. Obtained data has been compared to profiles calculated in the same axes by Nucletron-Oldelft BPS. Results: The lack of scattering in the region close to water surface (up to 8cm) results in significant drop in measured dose. The decrease depends both on the distance from the medium border and on the distance from the source. For source-to-detector distance of 6.5cm the difference between calculated and measured dose is 8% for 3cm and 21% for 1cm of water above the source. Profiles in this region become flattened and asymmetric according to the drop in dose level. Conclusions: The lack of scattering in the region close to the patient skin results in significant drop in dose which is not taken into account by Nucletron-Oldelft BPS. This means that dose distribution calculated in this region by the System is not correct

  8. Identification of Anaplasma marginale type IV secretion system effector proteins.

    Directory of Open Access Journals (Sweden)

    Svetlana Lockwood

    Full Text Available Anaplasma marginale, an obligate intracellular alphaproteobacterium in the order Rickettsiales, is a tick-borne pathogen and the leading cause of anaplasmosis in cattle worldwide. Complete genome sequencing of A. marginale revealed that it has a type IV secretion system (T4SS. The T4SS is one of seven known types of secretion systems utilized by bacteria, with the type III and IV secretion systems particularly prevalent among pathogenic Gram-negative bacteria. The T4SS is predicted to play an important role in the invasion and pathogenesis of A. marginale by translocating effector proteins across its membrane into eukaryotic target cells. However, T4SS effector proteins have not been identified and tested in the laboratory until now.By combining computational methods with phylogenetic analysis and sequence identity searches, we identified a subset of potential T4SS effectors in A. marginale strain St. Maries and chose six for laboratory testing. Four (AM185, AM470, AM705 [AnkA], and AM1141 of these six proteins were translocated in a T4SS-dependent manner using Legionella pneumophila as a reporter system.The algorithm employed to find T4SS effector proteins in A. marginale identified four such proteins that were verified by laboratory testing. L. pneumophila was shown to work as a model system for A. marginale and thus can be used as a screening tool for A. marginale effector proteins. The first T4SS effector proteins for A. marginale have been identified in this work.

  9. Methods and criterions for IV generation system choice

    International Nuclear Information System (INIS)

    Carre, F; Fiorini, G. L.

    2005-01-01

    The international forum of IV generation has been built up in 2000, initiated by the American Energy Department with an initial participation of nine countries (and of ten today). In a primary phase of these works, which was finished in October 2002, the forum objects were to define the list of nuclear systems conditions which could be ready to use in 2030 to make a sustainable energy development, and select previously the most promising technology to attain these purposes. This article presents, with its trumps and limits, the methodology which was used to select, starting from 120 propositions, one set of 6 systems which includes key technologies for the nuclears of the 21st century. (Authors)

  10. Anamnesis and the Silent Narrator in Plato and John

    Directory of Open Access Journals (Sweden)

    George L. Parsenios

    2017-03-01

    Full Text Available The Gospel of John is often compared to the dialogues of Plato by those who connect Johannine theology and Platonic philosophy. The comparison operates on the level of ideas. The present paper does not ignore issues of theology and philosophy but grounds a comparison of John and Plato first and foremost on the literary level. In several key places in John 1, 3, and 14, the Johannine narrator recedes from view and is unexpectedly silent where one would expect a narrator’s comment to organize the conversations and interactions between characters in John. Plato also renders the voice of the narrator silent in a dialogue like the Theaetetus. This paper argues that John and Plato both suppress the narrator’s voice in order to further their anamnetic efforts and to make later generations not only readers but participants in their original conversations.

  11. 1 Plato's Theories of Knowledge and Education: an Examination of ...

    African Journals Online (AJOL)

    Ngozi Ezenwa-Ohaeto

    doing introduced some of the most insightful theories of knowledge that ..... major deductions he makes from that quotation (but does not explain), are: (i). That Plato 'assumes' that there is 'a pre- linguistic realm whose representation either.

  12. Isocrates and Plato on Rhetoric and Rhetorical Education.

    Science.gov (United States)

    Benoit, William L.

    1991-01-01

    Compares the views of Isocrates and Plato on rhetoric and rhetorical education. Elucidates their criticisms of the sophists, their general assumptions about the nature and function of rhetoric, and their views on rhetorical education. (PRA)

  13. Rationality and Motivation: Moral Psychology in Plato's Socratic Dialogues

    OpenAIRE

    Neiders, Ivars

    2011-01-01

    "Rationality and Motivation: Moral Psychology in Plato's Socratic Dialogues" Annotation The dissertation "Rationality and Motivation: Moral Psychology in Plato's Socratic Dialogues" is a philosophical study of Socratic views in moral psychology. Particular attention is paid to what the author calls (1) Doxastic competence and (2) Orectic competence. It is argued that according to Socrates these two different epistemic relations are important aspects of our self-understanding. The doxast...

  14. Thermodynamic properties of actinide complexes. IV. Thorium(IV)- and uranyl(VI)-malonate systems

    Energy Technology Data Exchange (ETDEWEB)

    Di Bernardo, P; Di Napoli, V; Cassol, A; Magon, L [Consiglio Nazionale delle Ricerche, Padua (Italy). Lab. di Chimica e Tecnologia dei Radioelementi

    1977-01-01

    The stability constants and the enthalpies of formation of thorium(IV)- and uranyl(VI)-malonate complexes have been determined by potentiometric and calorimetric titrations in 1.00 M solutions of Na(ClO/sub 4/) at 25/sup 0/C. All complexes formed are found to be stabilized by a large entropy gain. The values for the stability constants agree with an ionic bonding model. The malonate behaves as a bidentate ligand forming only chelate complexes.

  15. Three Aspects of PLATO Use at Chanute AFB: CBE Production Techniques, Computer-Aided Management, Formative Development of CBE Lessons.

    Science.gov (United States)

    Klecka, Joseph A.

    This report describes various aspects of lesson production and use of the PLATO system at Chanute Air Force Base. The first chapter considers four major factors influencing lesson production: (1) implementation of the "lean approach," (2) the Instructional Systems Development (ISD) role in lesson production, (3) the transfer of…

  16. Good and Bad: Love and Intimacy From Plato to Melanie Klein.

    Science.gov (United States)

    Stromberg, David

    2018-06-01

    Melanie Klein's theories on love outline a complex system of relations-an oscillating dynamic of psychical and emotional tendencies following from both actual experience and fantasies produced by the mind. Her insights are often discussed and applied in psychoanalytical contexts, but the philosophical implications of her theory-especially in relation to Platonic thought-have rarely been discussed. In this article, I will attempt to address this gap by setting out some preliminary yet core considerations shared by both Plato and Klein. First, I will describe some structural parallels between Kleinian and Platonic thought, especially in dialectical terms. Second, I will outline Plato's covert influence on Freud as passing through the teachings of philosopher Franz Brentano. And last, I will discuss intimacy as a struggle between the forces of good and bad, creativity and destruction, and love and hate-suggesting that Klein's conception of love emerges as a moral exigency.

  17. The I-V Measurement System for Solar Cells Based on MCU

    International Nuclear Information System (INIS)

    Chen Fengxiang; Ai Yu; Wang Jiafu; Wang Lisheng

    2011-01-01

    In this paper, an I-V measurement system for solar cells based on Single-chip Microcomputer (MCU) is presented. According to the test principles of solar cells, this measurement system mainly comprises of two parts-data collecting, data processing and displaying. The MCU mainly used as to acquire data, then the collecting results is sent to the computer by serial port. The I-V measurement results of our test system are shown in the human-computer interaction interface based on our hardware circuit. By comparing the test results of our I-V tester and the results of other commercial I-V tester, we found errors for most parameters are less than 5%, which shows our I-V test result is reliable. Because the MCU can be applied in many fields, this I-V measurement system offers a simple prototype for portable I-V tester for solar cells.

  18. The I-V Measurement System for Solar Cells Based on MCU

    Energy Technology Data Exchange (ETDEWEB)

    Chen Fengxiang; Ai Yu; Wang Jiafu; Wang Lisheng, E-mail: phonixchen79@yahoo.com.cn [Department of physics science and technology, Wuhan University of Technology, Wuhan city, Hubei Province, 430070 (China)

    2011-02-01

    In this paper, an I-V measurement system for solar cells based on Single-chip Microcomputer (MCU) is presented. According to the test principles of solar cells, this measurement system mainly comprises of two parts-data collecting, data processing and displaying. The MCU mainly used as to acquire data, then the collecting results is sent to the computer by serial port. The I-V measurement results of our test system are shown in the human-computer interaction interface based on our hardware circuit. By comparing the test results of our I-V tester and the results of other commercial I-V tester, we found errors for most parameters are less than 5%, which shows our I-V test result is reliable. Because the MCU can be applied in many fields, this I-V measurement system offers a simple prototype for portable I-V tester for solar cells.

  19. Generation IV nuclear energy systems: road map and concepts. 2. Generation II Measurement Systems for Generation IV Nuclear Power Plants

    International Nuclear Information System (INIS)

    Miller, Don W.

    2001-01-01

    need for substantial research. As we consider I and C systems in Generation IV reactors, we have the opportunity to take a much less 'timid' design philosophy than was taken in the design of I and C systems in the ALWRs. We need to make use of advanced technology to design an I and C system for the Generation IV multi-unit plant designs currently being considered. Such a design should accomplish the following: 1. provides for multi-unit control; 2. contributes to a plant design objective of a very low core damage frequency; 3. maximizes plant thermal efficiency (>50%); 4. maximizes plant capacity factor (>90%); 5. optimizes operability; 6. maximizes maintainability; 7. provides for on-line monitoring, calibration, and diagnostics; 8. provides optimum response to disturbances; 9. provides excellent load-following capability. When we consider the current situation in operating Generation I and II nuclear power plants and even Generation III ALWR design, we conclude that Generation IV reactors should employ at least Generation II measurement systems. Let us first consider data transmission, which is a form of communication, and ask the question: Do new communication-transferring methods by electrons flow in copper wires? The obvious answer is no. Virtually all new communication systems are using some electromagnetic method, such as light, microwaves, HF or VHF radio signals, and virtually no copper wires. When we envision Generation IV nuclear power plants, we should minimize the use of copper wires for data transmission. We should transmit data primarily by fiber optics and various wireless methods, some of which can penetrate thick barriers. Now let us consider sensors. If we use light for data transmission, then we should also use optical-based sensors. We should also take advantage of microprocessors, which provide opportunities to embed 'intelligence' in the sensor that can be used to increase accuracy, stability, and tolerance to external stressors (i.e., radiation

  20. Plato, Nightingale, and Nursing: Can You Hear Me Now?

    Science.gov (United States)

    Arnone, Jacqueline Michele; Fitzsimons, Virginia

    2015-10-01

    A historical perspective on how the writings of Plato influenced Florence Nightingale in the formation of nursing as a respected profession for women. Comparing Nightingale's life and legacy to Platonic philosophy demonstrates how philosophy continues to speak to the profession of nursing practice as guardians of society in the 21st century. A review of the literature using EBSCO, SAGEpub, MEDLINE, and CINAHL databases and hand searches of literature were initiated for the years 1990-2014 using the terms "Plato," "Nightingale," and "nursing" restricted to English. Florence Nightingale, known as the mother of modern-day nursing, embodied her life and work after the philosophic tenets of Plato. Plato's Allegory of the Cave influenced Nightingale's attitudes with regard to the value of education, knowledge of the good, and the importance of imparting learned knowledge to others. Plato's work spoke of educating both men and women to seek the truth, affording both sexes to become competent as future leaders in the role of guardians to society. Nightingale's emphasis of education for women as a conduit for their usefulness to society mirrored Plato's philosophy. Over 100 years after her death, the impact Florence Nightingale still has on professional nursing practice remains. Scholarship in nursing education today is infused with a liberal arts background in philosophy, ethics, and the sciences. Nightingale's holistic concepts of person, health, and environment in the practice of nursing coalesced with her statistical analyses in validating nursing actions foreshadowed the development of universal nursing knowledge and language base and meta-paradigm concepts in nursing. Further classification and categorization of Nightingale's concepts of assessing, implementing, and evaluating delivery of care became the linguistic precursors for the identification of nursing process, nursing actions, and nursing diagnoses. Plato's and Nightingale's holistic, scientific, and

  1. Plato: A localised orbital based density functional theory code

    Science.gov (United States)

    Kenny, S. D.; Horsfield, A. P.

    2009-12-01

    The Plato package allows both orthogonal and non-orthogonal tight-binding as well as density functional theory (DFT) calculations to be performed within a single framework. The package also provides extensive tools for analysing the results of simulations as well as a number of tools for creating input files. The code is based upon the ideas first discussed in Sankey and Niklewski (1989) [1] with extensions to allow high-quality DFT calculations to be performed. DFT calculations can utilise either the local density approximation or the generalised gradient approximation. Basis sets from minimal basis through to ones containing multiple radial functions per angular momenta and polarisation functions can be used. Illustrations of how the package has been employed are given along with instructions for its utilisation. Program summaryProgram title: Plato Catalogue identifier: AEFC_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEFC_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 219 974 No. of bytes in distributed program, including test data, etc.: 1 821 493 Distribution format: tar.gz Programming language: C/MPI and PERL Computer: Apple Macintosh, PC, Unix machines Operating system: Unix, Linux and Mac OS X Has the code been vectorised or parallelised?: Yes, up to 256 processors tested RAM: Up to 2 Gbytes per processor Classification: 7.3 External routines: LAPACK, BLAS and optionally ScaLAPACK, BLACS, PBLAS, FFTW Nature of problem: Density functional theory study of electronic structure and total energies of molecules, crystals and surfaces. Solution method: Localised orbital based density functional theory. Restrictions: Tight-binding and density functional theory only, no exact exchange. Unusual features: Both atom centred and uniform meshes available

  2. Eugenics concept: from Plato to present.

    Science.gov (United States)

    Güvercin, C H; Arda, B

    2008-01-01

    All prospective studies and purposes to improve cure and create a race that would be exempt of various diseases and disabilities are generally defined as eugenic procedures. They aim to create the "perfect" and "higher" human being by eliminating the "unhealthy" prospective persons. All of the supporting actions taken in order to enable the desired properties are called positive eugenic actions; the elimination of undesired properties are defined as negative eugenics. In addition, if such applications and approaches target the public as a whole, they are defined as macro-eugenics. On the other hand, if they only aim at individuals and/or families, they are called micro-eugenics. As generally acknowledged, Galton re-introduced eugenic proposals, but their roots stretch as far back as Plato. Eugenic thoughts and developments were widely accepted in many different countries beginning with the end of the 19th to the first half of the 20th centuries. Initially, the view of negative eugenics that included compulsory sterilizations of handicapped, diseased and "lower" classes, resulted in tens of thousands being exterminated especially in the period of Nazi Germany. In the 1930s, the type of micro positive eugenics movement found a place within the pro-natalist policies of a number of countries. However, it was unsuccessful since the policy was not able to become effective enough and totally disappeared in the 1960s. It was no longer a fashionable movement and left a deep impression on public opinion after the long years of war. However, developments in genetics and its related fields have now enabled eugenic thoughts to reappear under the spotlight and this is creating new moral dilemmas from an ethical perspective.

  3. Plato, Aristotle and the phytagorean influence on Plutarch's De Musica

    Directory of Open Access Journals (Sweden)

    Roosevelt Rocha

    2012-07-01

    Full Text Available In his treatise On Music, Plutarch cites and discusses excerpts from works of Plato and Aristotle in which these authors deal with issues relevant to the harmonic theory. In these passages, we see that the sources used by Plutarch have a strong influence of the Pythagorean school, under which the study of musical scales was developed focusing on the mathematical relationships that exist between the notes and intervals. This indicates that Plutarch or not directly read the texts of Plato and Aristotle, or read, but using some other source, a commentator of Pythagorean extraction, who we can not identify.

  4. Plato's Cosmic Theology: A Rationale for a Polytheistic Astrology?

    Science.gov (United States)

    Henriques, André

    2015-05-01

    Plato's cosmology influenced classical astronomy and religion, but was in turn influenced by the polytheistic context of its time. Throughout his texts, including the cosmological treatise Timaeus, and the discussions on the soul in the Phaedrus, Plato (c.428-c.348 BC) established what can be generalised as Platonic cosmological thought. An understanding of the philosophical and mythical levels of Platonic thought can provide a rationale for polytheistic and astrological worldviews, pointing to some cosmological continuity, alongside major shifts, from ancient Greek religion to the astrological thought of ancient astronomers such as Claudius Ptolemy.

  5. Expected asteroseismic performances with the space project PLATO

    Directory of Open Access Journals (Sweden)

    Goupil Mariejo

    2017-01-01

    Full Text Available The PLATO (PLAnetary Transits and Oscillations of star space project will observe about fifty percents of the sky with the main purpose of detecting, confirming and characterizing transiting exoplanets of (superEarth sizes in the habitable zone of solar-like stars. Determining masses, radii and ages of exoplanets require the knowledge the masses, radii and ages of the host stars. We give a brief presentation of the main features of the mission. We then discuss some expected seismic performances of PLATO for characterizing bright solar-like stars, focusing on the challenging determination of accurate/precise stellar ages.

  6. The necessity of dialectics according to Plato and Adorno

    DEFF Research Database (Denmark)

    Olsen, Anne-Marie Eggert

    2009-01-01

    The paper deals with the notion of philosophy as, on the one hand, an academic or scientific discipline and, on the other, something perhaps superior to the disciplines and in any case dealing with what is not a 'disciplinary' matter. Through an interpretation of Plato's concept of dialectics and...

  7. Plato and Play: Taking Education Seriously in Ancient Greece

    Science.gov (United States)

    D'Angour, Armand

    2013-01-01

    In this article, the author outlines Plato's notions of play in ancient Greek culture and shows how the philosopher's views on play can be best appreciated against the background of shifting meanings and evaluations of play in classical Greece. Play--in various forms such as word play, ritual, and music--proved central to the development of…

  8. Plato, Freud and Marx on Human Nature: A Comparative Analysis ...

    African Journals Online (AJOL)

    This paper examines the conceptions of human nature by Plato, Sigmund Freud and Karl Marx, with a view to revealing and explaining the convergence and divergence between these conceptions. It shows that agreement or disagreement on the distinguishing characteristics of human individuals can be situated on ...

  9. Three Misunderstandings of Plato's Theory of Moral Education

    Science.gov (United States)

    Jonas, Mark E.

    2016-01-01

    In this essay, Mark Jonas argues that there are three broadly held misconceptions of Plato's philosophy that work against his relevance for contemporary moral education. The first is that he is an intellectualist who is concerned only with the cognitive aspect of moral development and does not sufficiently emphasize the affective and conative…

  10. Go Tell Alcibiades: Tragedy, Comedy, and Rhetoric in Plato's "Symposium"

    Science.gov (United States)

    Crick, Nathan; Poulakos, John

    2008-01-01

    Plato's "Symposium" is a significant but neglected part of his elaborate and complex attitude toward rhetoric. Unlike the intellectual discussion of the "Gorgias" or the unscripted conversation of the "Phaedrus," the "Symposium" stages a feast celebrating and driven by the forces of "Eros." A luxuriously stylish performance rather than a rational…

  11. Painlevé IV Hamiltonian systems and coherent states

    International Nuclear Information System (INIS)

    Bermudez, D; Contreras-Astorga, A; Fernández C, D J

    2015-01-01

    Schrödinger Hamiltonians with third-order differential ladder operators are linked to the Painlevé IV equation. Some of these appear from applying SUSY QM to the harmonic oscillator. Departing from them, we will build coherent states as eigenstates of the annihilation operator, then as displaced versions of the extremal states, both involving the third-order ladder operators, and finally as displaced extremal states using linearized ladder operators. To each Hamiltonian corresponds two families of coherent states for fixed ladder operators: one in the infinite dimension subspace associated with the oscillator spectrum and another in the finite dimension one generated by the eigenstates created by SUSY QM. (paper)

  12. On-ground and in-orbit characterisation plan for the PLATO CCD normal cameras

    Science.gov (United States)

    Gow, J. P. D.; Walton, D.; Smith, A.; Hailey, M.; Curry, P.; Kennedy, T.

    2017-11-01

    PLAnetary Transits and Ocillations (PLATO) is the third European Space Agency (ESA) medium class mission in ESA's cosmic vision programme due for launch in 2026. PLATO will carry out high precision un-interrupted photometric monitoring in the visible band of large samples of bright solar-type stars. The primary mission goal is to detect and characterise terrestrial exoplanets and their systems with emphasis on planets orbiting in the habitable zone, this will be achieved using light curves to detect planetary transits. PLATO uses a novel multi- instrument concept consisting of 26 small wide field cameras The 26 cameras are made up of a telescope optical unit, four Teledyne e2v CCD270s mounted on a focal plane array and connected to a set of Front End Electronics (FEE) which provide CCD control and readout. There are 2 fast cameras with high read-out cadence (2.5 s) for magnitude ~ 4-8 stars, being developed by the German Aerospace Centre and 24 normal (N) cameras with a cadence of 25 s to monitor stars with a magnitude greater than 8. The N-FEEs are being developed at University College London's Mullard Space Science Laboratory (MSSL) and will be characterised along with the associated CCDs. The CCDs and N-FEEs will undergo rigorous on-ground characterisation and the performance of the CCDs will continue to be monitored in-orbit. This paper discusses the initial development of the experimental arrangement, test procedures and current status of the N-FEE. The parameters explored will include gain, quantum efficiency, pixel response non-uniformity, dark current and Charge Transfer Inefficiency (CTI). The current in-orbit characterisation plan is also discussed which will enable the performance of the CCDs and their associated N-FEE to be monitored during the mission, this will include measurements of CTI giving an indication of the impact of radiation damage in the CCDs.

  13. Technology Road-map Update for Generation IV Nuclear Energy Systems

    International Nuclear Information System (INIS)

    2014-01-01

    This Technology Road-map Update provides an assessment of progress made by the Generation IV International Forum (GIF) in the development of the six systems selected when the original Technology Road-map was published in 2002. More importantly, it provides an overview of the major R and D objectives and milestones for the coming decade, aiming to achieve the Generation IV goals of sustainability, safety and reliability, economic competitiveness, proliferation resistance and physical protection. Lessons learnt from the Fukushima Daiichi nuclear power plant accident are taken into account to ensure that Generation IV systems attain the highest levels of safety, with the development of specific safety design criteria that are applicable across the six systems. Accomplishing the ten-year R and D objectives set out in this new Road-map should allow the more advanced Generation IV systems to move towards the demonstration phase. (authors)

  14. Analysis of criticality using NJOY, AMPX-II and KENO-IV systems

    International Nuclear Information System (INIS)

    Ferreira, C.R.; Santos, A. dos

    1989-01-01

    Trough a linking between the nuclear data code systems NJOY and AMPX-II, performed at Divisao de Fisica de Reatores-IPEN, it was made criticality analysis with the KENO-IV in two fast multiplying systems: JEZEBEL and GODIVA. The ENDF/B-IV and JENDL-2 was used throughout the analysis. It was found that the linking between NJOY and AMPX-II systems can be suitable for a benchmark calculation of neutron cross sections. The KENO-IV code cannot be applied in systems where the degree of anisotropic scattering is too high because this computer code treats scattering up to first order. The XSDRNPM results show that the results obtained with ENDF/B-IV are of better quality than those obtained with JENDL-2. (author) [pt

  15. 45 CFR 310.5 - What options are available for Computerized Tribal IV-D Systems and office automation?

    Science.gov (United States)

    2010-10-01

    ... IV-D Systems and office automation? 310.5 Section 310.5 Public Welfare Regulations Relating to Public... AUTOMATION Requirements for Computerized Tribal IV-D Systems and Office Automation § 310.5 What options are available for Computerized Tribal IV-D Systems and office automation? (a) Allowable computerized support...

  16. Slovenian test case Vrbanski Plato aquifer in the EU HORIZON 2020 FREEWAT project

    Directory of Open Access Journals (Sweden)

    Irena Kopač

    2017-09-01

    Full Text Available The Slovenian case study in the EU HORIZON 2020 FREEWAT project was Vrbanski Plato aquifer. Slovenia is divided into two river basin districts: the Danube and the North Adriatic. The Vrbanski Plato aquifer, which he presents both natural and artificial bank filtration from the river Drava, is a part of the Danube river basin district and is the most important water source for 14 municipalities in the northeastern part of Slovenia. We investigated the groundwatersurface water interaction between river Drava and the porous aquifer in the geological old riverbed and possible reduction of city impact. This site is the oldest managed artificial groundwater recharge with riverbank filtration and has more than thirty years of successful operation. It is something special, very abundant in a small space, independent of drought and climate changes, but vulnerable due to the impact of the city. Under the city there is watershed dividing, which is shifting with different water management condition and we would like to have the least possible impact of the city. For optimal water management we decided to use FREEWAT plug-in within QGIS platform. With new developed FREEWAT plug-in in project FREEWAT, we made steady-state and transient groundwater model for presenting this shift of the watershed dividing under the city and optimal water management for this area. The model was designed in a way that it identifies and describes all major aspects of the physical hydrogeological system and water management. During the running of a project, there was an accident with heating oil spillage in city area, right on the watershed dividing. So we oriented with the transient groundwater model as well on heating oil spillage and pumping with additional wells at the place of the accident to present successful rehabilitation and the importance of the managed groundwater recharge. Our experience with FREEWAT platform during the Vrbanski Plato aquifer case study was very

  17. Implementation of SAP-IV on a minicomputer disc operating system

    International Nuclear Information System (INIS)

    Spencer, R.B.; Howard, G.E.

    1977-01-01

    The objective of the described effort was the implementation of a linear elastic finite element structural analysis program version on a minicomputer operating system while maintaining (as much as possible) the general features of the original program. SAP-IV has been successfully implemented on a minicomputer operating system as one component in a portable vibration testing, data acquisition and processing, parameter identification and design optimization system for field work. The primary features in SAP-IV facilitating conversion and implementation on a minicomputer are: (1) the calculational procedures of SAP-IV are well documented and the subroutine structure easy to follow; (2) SAP-IV is organized in a highly modular fashion; (3) it is versatile with respect to its calculational options; and (4) the element library can be readily expanded. (Auth.)

  18. DEVELOPMENT OF RISK-BASED AND TECHNOLOGY-INDEPENDENT SAFETY CRITERIA FOR GENERATION IV SYSTEMS

    Energy Technology Data Exchange (ETDEWEB)

    William E. Kastenberg; Edward Blandford; Lance Kim

    2009-03-31

    This project has developed quantitative safety goals for Generation IV (Gen IV) nuclear energy systems. These safety goals are risk based and technology independent. The foundations for a new approach to risk analysis has been developed, along with a new operational definition of risk. This project has furthered the current state-of-the-art by developing quantitative safety goals for both Gen IV reactors and for the overall Gen IV nuclear fuel cycle. The risk analysis approach developed will quantify performance measures, characterize uncertainty, and address a more comprehensive view of safety as it relates to the overall system. Appropriate safety criteria are necessary to manage risk in a prudent and cost-effective manner. This study is also important for government agencies responsible for managing, reviewing, and for approving advanced reactor systems because they are charged with assuring the health and safety of the public.

  19. DEVELOPMENT OF RISK-BASED AND TECHNOLOGY-INDEPENDENT SAFETY CRITERIA FOR GENERATION IV SYSTEMS

    International Nuclear Information System (INIS)

    Kastenberg, William E.; Blandford, Edward; Kim, Lance

    2009-01-01

    This project has developed quantitative safety goals for Generation IV (Gen IV) nuclear energy systems. These safety goals are risk based and technology independent. The foundations for a new approach to risk analysis has been developed, along with a new operational definition of risk. This project has furthered the current state-of-the-art by developing quantitative safety goals for both Gen IV reactors and for the overall Gen IV nuclear fuel cycle. The risk analysis approach developed will quantify performance measures, characterize uncertainty, and address a more comprehensive view of safety as it relates to the overall system. Appropriate safety criteria are necessary to manage risk in a prudent and cost-effective manner. This study is also important for government agencies responsible for managing, reviewing, and for approving advanced reactor systems because they are charged with assuring the health and safety of the public

  20. THE JOURNEY OF TRUTH: FROM PLATO TO ZOLA

    Directory of Open Access Journals (Sweden)

    Ribut Basuki

    1999-01-01

    Full Text Available Western theater theory and criticism is generally considered to be set forth by the Greeks. Plato was "the first theater critic" with his negative comments about theater owing to his idealistic views about "the truth." Then came Aristotle who used a different viewpoint from that of Plato, saying that there is "truth" in theater. However, hostile criticism on theater came back in the Middle Ages, championed by Tertulian before Aristotelian theory was revived by the neo-classicists such as Scaliger and Castelvetro. Theater theory and criticism discourse was then made more alive by the romanticists who disagreed with the neo-classicists' rigid rules on theater. As the influence of science became dominant in the theater world, naturalism and realism emerged and became the mainstream of theater theory and criticism until well into the twentieth century.

  1. Explorations of new phases in the Ga(III)/In(III)-Mo(VI)-Se(IV)/Te(IV)-O systems.

    Science.gov (United States)

    Kong, Fang; Hu, Chun-Li; Hu, Ting; Zhou, Yong; Mao, Jiang-Gao

    2009-07-07

    Systematic explorations of new phases in the Ga(III)/In(III)-Mo(VI)-Se(IV)/Te(IV)-O systems by hydrothermal syntheses or solid-state reactions at high-temperature led to four new quaternary compounds, namely, Ga(2)MoQ(2)O(10) (Q = Se, Te), In(2)Mo(2)Se(2)O(13)(H(2)O) and In(2)MoTe(2)O(10). Ga(2)MoQ(2)O(10) (Q = Se, Te) are isostructural and their structures feature a 3D network of gallium selenite/tellurite with 12-member ring tunnels along b-axis, the distorted MoO(6) octahedra are attached on the wall of the above tunnels. The structure of In(2)Mo(2)Se(2)O(13)(H(2)O) features a new pillared-layered architecture composed of 2D indium(III) selenite layers that are interconnected by Mo(2)O(10) dimers, forming 8-membered ring tunnels along the b-axis. The structure of In(2)MoTe(2)O(10) features a 2D indium oxide layer formed by corner- and edge-sharing InO(6) and InO(7) polyhedra with MoO(4) tetrahedra and TeO(n) (n = 4, 5) polyhedra hanging on both sides of the layer, there are weak interlayer Te-O bonds of 2.512 A. Results of optical diffuse reflectance spectrum measurements indicate that all four compounds are insulators, which are in agreement with results of band structure calculations based on DFT methods.

  2. Approach to the problem of motion in Plato

    Directory of Open Access Journals (Sweden)

    Ignacio García Peña

    2013-07-01

    Full Text Available Since the first philosophers began to reflect about the idea of nature, the problem of motion became a crucial topic in their discussions. The entire pre-Socratic tradition was gathered by Plato, whose reflections are often triggered by fragments of Parmenides and Heraclitus. The Athenian philosopher analyzed motion in relation to the visible and intelligible regions that he distinguishes in the sphere of reality, as well as the fine line that links it to the soul

  3. Plato and Aristotle on the Problem of Quality

    OpenAIRE

    Santa Cruz, María Isabel

    2013-01-01

    This paper purports toshow that it is not necessary to read the early Platonic dialogues starting from the "classic" theory of Forms. It argues, instead, that it is possibleto analyze them and, above all, to explain the use of the vocabulary of "presence" starting from the more general and prior possibility of distinguishing a subject from its accidental predicates, especially quality. The relation of "present in" or "being in" to which Plato recurs. is inherited by Aristotle. The distinction...

  4. Making System Dynamics Cool IV : Teaching & Testing with Cases & Quizzes

    NARCIS (Netherlands)

    Pruyt, E.

    2012-01-01

    This follow-up paper presents cases and multiple choice questions for teaching and testing System Dynamics modeling. These cases and multiple choice questions were developed and used between January 2012 and April 2012 a large System Dynamics course (250+ 2nd year BSc and 40+ MSc students per year)

  5. THE ELM SURVEY. IV. 24 WHITE DWARF MERGER SYSTEMS

    International Nuclear Information System (INIS)

    Kilic, Mukremin; Brown, Warren R.; Kenyon, S. J.; Allende Prieto, Carlos; Heinke, Craig O.; Agüeros, M. A.; Kleinman, S. J.

    2012-01-01

    We present new radial velocity and X-ray observations of extremely low mass (ELM, ∼0.2 M ☉ ) white dwarf (WD) candidates in the Sloan Digital Sky Survey Data Release 7 area. We identify seven new binary systems with 1-18 hr orbital periods. Five of the systems will merge due to gravitational wave radiation within 10 Gyr, bringing the total number of merger systems found in the ELM Survey to 24. The ELM Survey has now quintupled the known merger WD population. It has also discovered the eight shortest period detached binary WD systems currently known. We discuss the characteristics of the merger and non-merger systems observed in the ELM Survey, including their future evolution. About half of the systems have extreme mass ratios. These are the progenitors of the AM Canum Venaticorum systems and Type Ia supernovae. The remaining targets will lead to the formation of extreme helium stars, subdwarfs, or massive WDs. We identify three targets that are excellent gravitational wave sources. These should be detected by the Laser Interferometer Space Antenna like missions within the first year of operation. The remaining targets are important indicators of what the Galactic foreground may look like for gravitational wave observatories.

  6. THE ELM SURVEY. IV. 24 WHITE DWARF MERGER SYSTEMS

    Energy Technology Data Exchange (ETDEWEB)

    Kilic, Mukremin [Homer L. Dodge Department of Physics and Astronomy, University of Oklahoma, 440 West Brooks Street, Norman, OK 73019 (United States); Brown, Warren R.; Kenyon, S. J. [Smithsonian Astrophysical Observatory, 60 Garden Street, Cambridge, MA 02138 (United States); Allende Prieto, Carlos [Instituto de Astrofisica de Canarias, E-38205 La Laguna, Tenerife (Spain); Heinke, Craig O. [Department of Physics, CCIS 4-183, University of Alberta, Edmonton, AB, T6G 2E1 (Canada); Agueeros, M. A. [Department of Astronomy, Columbia University, 550 West 120th Street, New York, NY 10027 (United States); Kleinman, S. J., E-mail: kilic@ou.edu [Gemini Observatory, 670 North A' ohoku Place, Hilo, HI 96720 (United States)

    2012-06-01

    We present new radial velocity and X-ray observations of extremely low mass (ELM, {approx}0.2 M{sub Sun }) white dwarf (WD) candidates in the Sloan Digital Sky Survey Data Release 7 area. We identify seven new binary systems with 1-18 hr orbital periods. Five of the systems will merge due to gravitational wave radiation within 10 Gyr, bringing the total number of merger systems found in the ELM Survey to 24. The ELM Survey has now quintupled the known merger WD population. It has also discovered the eight shortest period detached binary WD systems currently known. We discuss the characteristics of the merger and non-merger systems observed in the ELM Survey, including their future evolution. About half of the systems have extreme mass ratios. These are the progenitors of the AM Canum Venaticorum systems and Type Ia supernovae. The remaining targets will lead to the formation of extreme helium stars, subdwarfs, or massive WDs. We identify three targets that are excellent gravitational wave sources. These should be detected by the Laser Interferometer Space Antenna like missions within the first year of operation. The remaining targets are important indicators of what the Galactic foreground may look like for gravitational wave observatories.

  7. A computer-controlled conformal radiotherapy system. IV: Electronic chart

    International Nuclear Information System (INIS)

    Fraass, Benedick A.; McShan, Daniel L.; Matrone, Gwynne M.; Weaver, Tamar A.; Lewis, James D.; Kessler, Marc L.

    1995-01-01

    Purpose: The design and implementation of a system for electronically tracking relevant plan, prescription, and treatment data for computer-controlled conformal radiation therapy is described. Methods and Materials: The electronic charting system is implemented on a computer cluster coupled by high-speed networks to computer-controlled therapy machines. A methodical approach to the specification and design of an integrated solution has been used in developing the system. The electronic chart system is designed to allow identification and access of patient-specific data including treatment-planning data, treatment prescription information, and charting of doses. An in-house developed database system is used to provide an integrated approach to the database requirements of the design. A hierarchy of databases is used for both centralization and distribution of the treatment data for specific treatment machines. Results: The basic electronic database system has been implemented and has been in use since July 1993. The system has been used to download and manage treatment data on all patients treated on our first fully computer-controlled treatment machine. To date, electronic dose charting functions have not been fully implemented clinically, requiring the continued use of paper charting for dose tracking. Conclusions: The routine clinical application of complex computer-controlled conformal treatment procedures requires the management of large quantities of information for describing and tracking treatments. An integrated and comprehensive approach to this problem has led to a full electronic chart for conformal radiation therapy treatments

  8. A monequillibrium mary-body systems IV: Respouse function theory

    International Nuclear Information System (INIS)

    Luzzi, R.; Vasconcellos, A.R.; Algarte, A.C.S.

    1987-01-01

    A response function theory for many-body systems arbitrarily away from equilibrium is presented. It is based on the nonequilibrium statistical operator method fully described in a previous article. A formal theory is presented evaluation of transition probabilties and the average values of dynamical quantities in far-from-equilibrium many-body systems under the action of external perturbations. A nonequilibrium thermodynamic Green's function algorithn appropriate for the calculation of response functions and scattering cross sections in terms of a generalized fluctuation-dissipation theorem for far-from-equilibrium systems is also derived. (author) [pt

  9. Motion control system of MAX IV Laboratory soft x-ray beamlines

    International Nuclear Information System (INIS)

    Sjöblom, Peter; Lindberg, Mirjam; Forsberg, Johan; Persson, Andreas G.; Urpelainen, Samuli; Såthe, Conny

    2016-01-01

    At the MAX IV Laboratory, five new soft x-ray beamlines are under development. The first is Species and it will be used to develop and set the standard of the control system, which will be common across the facility. All motion axes at MAX IV will be motorized using stepper motors steered by the IcePAP motion controller and a mixture of absolute and incremental encoders following a predefined coordinate system. The control system software is built in Tango and uses the Python-based Sardana framework. The user controls the entire beamline through a synoptic overview and Sardana is used to run the scans.

  10. Motion control system of MAX IV Laboratory soft x-ray beamlines

    Energy Technology Data Exchange (ETDEWEB)

    Sjöblom, Peter, E-mail: peter.sjoblom@maxlab.lu.se; Lindberg, Mirjam, E-mail: mirjam.lindberg@maxlab.lu.se; Forsberg, Johan, E-mail: johan.forsberg@maxlab.lu.se; Persson, Andreas G., E-mail: andreas-g.persson@maxlab.lu.se; Urpelainen, Samuli, E-mail: samuli.urpelainen@maxlab.lu.se; Såthe, Conny, E-mail: conny.sathe@maxlab.lu.se [MAX IV Laboratory, Photongatan 2, 225 92 Lund (Sweden)

    2016-07-27

    At the MAX IV Laboratory, five new soft x-ray beamlines are under development. The first is Species and it will be used to develop and set the standard of the control system, which will be common across the facility. All motion axes at MAX IV will be motorized using stepper motors steered by the IcePAP motion controller and a mixture of absolute and incremental encoders following a predefined coordinate system. The control system software is built in Tango and uses the Python-based Sardana framework. The user controls the entire beamline through a synoptic overview and Sardana is used to run the scans.

  11. Monitoring and Fault Detection in Photovoltaic Systems Based On Inverter Measured String I-V Curves

    DEFF Research Database (Denmark)

    Spataru, Sergiu; Sera, Dezso; Kerekes, Tamas

    2015-01-01

    Most photovoltaic (PV) string inverters have the hardware capability to measure at least part of the current-voltage (I-V) characteristic curve of the PV strings connected at the input. However, this intrinsic capability of the inverters is not used, since I-V curve measurement and monitoring...... functions are not implemented in the inverter control software. In this paper, we aim to show how such a functionality can be useful for PV system monitoring purposes, to detect the presence and cause of power-loss in the PV strings, be it due to shading, degradation of the PV modules or balance......-of-system components through increased series resistance losses, or shunting of the PV modules. To achieve this, we propose and experimentally demonstrate three complementary PV system monitoring methods that make use of the I-V curve measurement capability of a commercial string inverter. The first method is suitable...

  12. Implementation of SAP-IV on a minicomputer disc operating system

    International Nuclear Information System (INIS)

    Spencer, R.B.; Howard, G.E.

    1977-01-01

    The objective of the described effort was the implementation of a linear elastic finite element structural analysis program version on a minicomputer operating system while maintaining (as much as possible) the general features of the original program. SAP-IV has been successfully implemented on a minicomputer operating system as one component in a portable vibration testing, data acquisition and processing, parameter identification and design optimization system for field work. The primary features in SAP-IV facilitating conversion and implementation on a minicomputer are: (1) the calculational procedures of SAP-IV are well documented and the subroutine structure easy to follow; (2) SAP-IV is organized in a highly modular fashion; (3) it is versatile with respect to its calculational options; and (4) the element library can be readily expanded. SAP-IV was installed on a Data General NOVA 32K memory disc operating system which utilizes various input-output peripherals and a single 1.2 megaword disc. The entire theoretical analysis-vibration test-data analysis-parameter identification-model modification system required such additional components as analog/digital converters, computer-driven electro-mechanical vibrators, a maximum of 512 transducers, and special-purpose software for test planning, execution, data processing, and matrix manipulation. The software system capabilities which allowed implementation of SAP-IV on the minicomputer were: (1) the availability of double precision; (2) the ability to use multiple OVERLAYs; (3) the ability to read and write programs from the disc to memory without destroying the programs (SWAP); (4) the ability to CHAIN a series of connected programs into the memory and execute them sequentially; and (5) the ability to utilize random access disc files

  13. Conservation of the Type IV secretion system throughout Wolbachia evolution

    DEFF Research Database (Denmark)

    Pichon, Samuel; Bouchon, Didier; Cordaux, Richard

    2009-01-01

    , encoding a T4SS were previously identified and characterized at two separate genomic loci. Using the largest data set of Wolbachia strains studied so far, we show that vir gene sequence and organization are strictly conserved among 37 Wolbachia strains inducing various phenotypes such as cytoplasmic...... incompatibility, feminization, or oogenesis in their arthropod hosts. In sharp contrast, extensive variation of genomic sequences flanking the virB8-D4 operon suggested its distinct location among Wolbachia genomes. Long term conservation of the T4SS may imply maintenance of a functional effector translocation...... system in Wolbachia, thereby suggesting the importance for the T4SS in Wolbachia biology and survival inside host cells....

  14. Electrochemistry and Spectroelectrochemistry of the Pu (III/IV) and (IV/VI) Couples in Nitric Acid Systems

    Energy Technology Data Exchange (ETDEWEB)

    Lines, Amanda M. [Nuclear Chemistry and Engineering, Pacific Northwest National Laboratory, Richland WA 99352; Adami, Susan R. [Nuclear Chemistry and Engineering, Pacific Northwest National Laboratory, Richland WA 99352; Casella, Amanda J. [Nuclear Chemistry and Engineering, Pacific Northwest National Laboratory, Richland WA 99352; Sinkov, Sergey I. [Nuclear Chemistry and Engineering, Pacific Northwest National Laboratory, Richland WA 99352; Lumetta, Gregg J. [Nuclear Chemistry and Engineering, Pacific Northwest National Laboratory, Richland WA 99352; Bryan, Samuel A. [Nuclear Chemistry and Engineering, Pacific Northwest National Laboratory, Richland WA 99352

    2017-09-20

    The solution chemistry of Pu in nitric acid is explored via electrochemistry and spectroelectrochemistry. By utilizing and comparing these techniques, an improved understanding of Pu behavior and its dependence on nitric acid concentration can be achieved. Here the Pu (III/IV) couple is characterized using cyclic voltammetry, square wave voltammetry, and a spectroelectrochemical Nernst step. Results indicate the formal reduction potential of the couple shifts negative with increasing acid concentration and reversible electrochemistry is no longer attainable above 6 M HNO3. Spectroelectrochemistry is also used to explore the irreversible oxidation of Pu(IV) to Pu(VI) and shine light on the mechanism and acid dependence of the redox reaction.

  15. Discourse, Dialectic and Intrapersonal Rhetoric: A Reinterpretation of Plato's Rhetorical Theory.

    Science.gov (United States)

    Hikins, James W.

    The idea that rhetoric might operate in epistemologically significant ways was first presented by Plato. This paper argues that the heart of Plato's conception of epistemic discourse is a recognition of the centrality of intrapersonal rhetoric. Through a careful study of Platonic writing, particularly the "Phaedrus," three principal…

  16. Worldly and Otherworldly Virtue: Likeness to God as Educational Ideal in Plato, Plotinus, and Today

    Science.gov (United States)

    Zovko, Marie-Élise

    2018-01-01

    In Plato, 'Becoming like God' constitutes the "telos" of the philosophical life. Our 'likeness to God' is rooted in the relationship of the divine paradeigma to its image established in the generation of the Cosmos. This relationship makes knowledge and virtue possible, and informs Plato's theory of education. Related concepts preexist…

  17. Plato and the Modern American "Right": Agendas, Assumptions, and the Culture of Fear

    Science.gov (United States)

    Ramsey, Paul

    2009-01-01

    This article presents an interpretation of Plato's "Republic" that has many striking similarities to the social agenda of modern educational conservatives in the United States, which is particularly timely because George W. Bush's administration is, at this writing, coming to an end. Plato's ideal city is best seen as one that promoted an…

  18. Reversing Plato’s Anti-Democratism: Castoriadis’ “Quirky” Plato

    Directory of Open Access Journals (Sweden)

    Hamblet, Wendy C.

    2008-12-01

    Full Text Available This paper considers the conflicting "loves" of Cornelius Castoriadis--his love for the ancients, and especially Plato, and for the common person of the demos. A detailed study of Castoriadis' analysis of Plato's Statesman exposes that Castoriadis attempts to resolve the paradox by rereading Plato as a radical democrat. I argue that this unorthodox reading is at best "quirky, " (a charge Castoriadis levels at Plato at worst a groundless sophism. However, I conjecture that Castoriadis' reading may not constitute a serious attempt to describe a Platonic politics, so much as a prescriptive reading of what otherwise might have been, given certain strands of political generosity evident elsewhere in Plato's corpus.

  19. PLATO: a computer code for the analysis of fission product plateout in HTGRs

    International Nuclear Information System (INIS)

    Suzuki, Katsuo; Morimoto, Toshio.

    1981-01-01

    The computer code PLATO for estimating plateout activities on surfaces of primary cooling system of HTGRs has been developed, and in this report, analytical model and digital calculation method incorporated in the code are described. The code utilizes the mass transfer model analogous to heat transfer coupled with an expression for adsorption-desorption phenomenon, and is able to analyze plateout behaviours in a closed circuit, like a reactor cooling system, which is constructed from a various kind of components, as well as in an open-ended tube. With the code, fission product concentration in the coolant and plateout amount on the surfaces are calculated along the coolant stream, and total removal rate by the plateout process is also obtained. Comparison of the analytical results with the experimental results, including checks of the effects of some calculation conditions on the results, and preliminary analysis on the VHTR plant have been made. (author)

  20. Journal of Sustainable Development of Energy, Water and Environment Systems – Volume IV

    Directory of Open Access Journals (Sweden)

    Neven Duić

    2016-12-01

    In total 32 manuscripts were published in Volume IV, all of them reviewed by at least two reviewers. The Journal of Sustainable Development of Energy, Water and Environment Systems would like to thank reviewers for their contribution to the quality of the published manuscripts.

  1. Library generation and tests for the HAMMER system from the ENDF/B-IV data

    International Nuclear Information System (INIS)

    Queiroz Bogado Leite, S. de; Chalhoub, E.S.; Moraes, Marisa de.

    1983-05-01

    The modifications made to a number of programs belonging to the HAMMER system in order to process data from ENDF/B-IV are presented. An alternate scheme of representing the resonance region by means of extensive tabulation of profiles is made available for selected materials. Numerical examples illustrate comparisons of the results obtained with these libraries against those from the literature. (Author) [pt

  2. Preparation, spectrometric analysis and determination of the electrochemical transport characteristics of uranium (IV) in aqueous systems

    International Nuclear Information System (INIS)

    Schwarzer, W.G.

    1985-01-01

    A process for the quantitative development of uranium-(IV) solutions in nitric and perchloric acid media was developed. After appropriate concentration setting of the solutions, the conductivity of the uranium (IV) in the dependence on concentration were analysed. The conversion of the measuring results on the standard system water was done by means of a conductivity theory; this allows a comparison with the conductivity data of other ions. The conductivity calculated, at an ion strength I tending to zero, provided the suitable data for the ion mobility and the transference number. (orig./PW) [de

  3. Design of Radiation-Tolerant Structural Alloys for Generation IV Nuclear Energy Systems

    Energy Technology Data Exchange (ETDEWEB)

    Allen, T.R.; Was, G.S.; Bruemmer, S.M.; Gan, J.; Ukai, S.

    2005-12-28

    The objective of this program is to improve the radiation tolerance of both austenitic and ferritic-martensitic (F-M) alloys projected for use in Generation IV systems. The expected materials limitations of Generation IV components include: creep strength, dimensional stability, and corrosion/stress corrosion compatibility. The material design strategies to be tested fall into three main categories: (1) engineering grain boundaries; (2) alloying, by adding oversized elements to the matrix; and (3) microstructural/nanostructural design, such as adding matrix precipitates. These three design strategies were tested across both austenitic and ferritic-martensitic alloy classes

  4. Aristotle vs. Plato: The Balkans' Paradoxical Enlightenment

    Directory of Open Access Journals (Sweden)

    D. Michalopoulos

    2007-09-01

    Full Text Available As it occurred in West, Aristotle’s thought was in Byzantium the main organon of philosophical meditation within the frame of the Christian Faith. Nonetheless, from the ninth century on it was a revival of Platonism that took place – of Neo-Platonism at the beginning and of Platonism itself at the end. The Church, initially indifferent, became suspicious only when, at the turning of the fourteenth to the fifteenth century, the Platonism seemed to engender somewhat a latent paganism; but the Patriarchate was not then able to fight that tendency. So only after the 1453 capture of Constantinople by the Ottomans, Gennadius Scholarius managed to root out from the Greek lands Platonism and its crypto-pagan extension. Be that as it may; the main paradox of the Balkan history is that in the early seventeenth century some leading Greek scholars endorsed the materialist interpretation of Aristotle’s thought – as it was taught in the University of Padua by Cesare Cremonini; and as a corollary this materialistic philosophical system began being taught in both Constantinople and Athens. It was that very way that the Enlightenment took birth in the Balkans – and somehow became a State ideology - long before its prevalence in France. And of course all this had as a result a turn toward Physics and Chemistry with far-reaching consequences

  5. Generation IV Nuclear Energy Systems Ten-Year Program Plan Fiscal Year 2005, Volume 1

    International Nuclear Information System (INIS)

    None

    2005-01-01

    As reflected in the U.S. ''National Energy Policy'', nuclear energy has a strong role to play in satisfying our nation's future energy security and environmental quality needs. The desirable environmental, economic, and sustainability attributes of nuclear energy give it a cornerstone position, not only in the U.S. energy portfolio, but also in the world's future energy portfolio. Accordingly, on September 20, 2002, U.S. Energy Secretary Spencer Abraham announced that, ''The United States and nine other countries have agreed to develop six Generation IV nuclear energy concepts''. The Secretary also noted that the systems are expected to ''represent significant advances in economics, safety, reliability, proliferation resistance, and waste minimization''. The six systems and their broad, worldwide research and development (R and D) needs are described in ''A Technology Roadmap for Generation IV Nuclear Energy Systems'' (hereafter referred to as the Generation IV Roadmap). The first 10 years of required U.S. R and D contributions to achieve the goals described in the Generation IV Roadmap are outlined in this Program Plan

  6. A Study on the Planning of Technology Development and Research for Generation IV Nuclear Energy Systems

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Moon Hee; Kim, H. R.; Kim, H. J. and others

    2005-08-15

    This study aimed at the planning the domestic technology development of the Gen IV and the formulating the international collaborative project contents and executive plan for 'A Validity Assessment and Policies of the R and D of Generation IV Nuclear Energy Systems'. The results of the study include follows; - Survey of the technology state in the fields of the Gen IV system specific technologies and the common technologies, and the plans of the international collaborative research - Drawing up the executive research and development plan by the experts of the relevant technology field for the systems which Korean will participate in. - Formulating the effective conduction plan of the program reflecting the view of the experts from the industry, the university and the research institute. - Establishing the plan for estimation of the research fund and the manpower for the efficient utilization of the domestic available resources. This study can be useful material for evaluating the appropriateness of the Korea's participation in the international collaborative development of the Gen IV, and can be valuably utilized to establish the strategy for the effective conduction of the program. The executive plan of the research and development which was produced in this study will be used to the basic materials for the establishing the guiding direction and the strategic conduction of the program when the research and development is launched in the future.

  7. 45 CFR 310.40 - What requirements apply for accessing systems and records for monitoring Computerized Tribal IV-D...

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false What requirements apply for accessing systems and records for monitoring Computerized Tribal IV-D Systems and Office Automation? 310.40 Section 310.40... COMPUTERIZED TRIBAL IV-D SYSTEMS AND OFFICE AUTOMATION Accountability and Monitoring Procedures for...

  8. DEVELOPMENT OF A METHODOLOGY TO ASSESS PROLIFERATION RESISTANCE AND PHYSICAL PROTECTION FOR GENERATION IV SYSTEMS

    International Nuclear Information System (INIS)

    Nishimura, R.; Bari, R.; Peterson, P.; Roglans-Ribas, J.; Kalenchuk, D.

    2004-01-01

    Enhanced proliferation resistance and physical protection (PR and PP) is one of the technology goals for advanced nuclear concepts, such as Generation IV systems. Under the auspices of the Generation IV International Forum, the Office of Nuclear Energy, Science and Technology of the U.S. DOE, the Office of Nonproliferation Policy of the National Nuclear Security Administration, and participating organizations from six other countries are sponsoring an international working group to develop an evaluation methodology for PR and PP. This methodology will permit an objective PR and PP comparison between alternative nuclear systems (e.g., different reactor types or fuel cycles) and support design optimization to enhance robustness against proliferation, theft and sabotage. The paper summarizes the proposed assessment methodology including the assessment framework, measures used to express the PR and PP characteristics of the system, threat definition, system element and target identification, pathway identification and analysis, and estimation of the measures

  9. Design and application of the MARK IV scanning system for radionuclide computed tomography of the brain

    International Nuclear Information System (INIS)

    Kuhl, D.E.; Hoffman, E.J.; Phelps, M.E.; Ricci, A.; Reivich, M.

    1976-01-01

    The MARK IV radioisotope scanning system was built to provide fast and accurate radionuclide computed tomography (RCT). It is designed primarily for detecting commonly available radioactive labels such as /sup 99m/Tc, but it is also adapted to detecting positron emitters such as 18 F. The system has interlaced convergent collimation in a 4-sided arrangement of 32-independent detectors which continuously rotate as a unit, detecting, processing, and displaying the reconstructed data while the study progresses

  10. Aerodynamic performance analysis of an airborne wind turbine system with NREL Phase IV rotor

    International Nuclear Information System (INIS)

    Saeed, Muhammad; Kim, Man-Hoe

    2017-01-01

    Highlights: • Aerodynamic predictions for a buoyant airborne system at an altitude of 400 m. • Aerodynamic characteristics of NREL Phase IV rotor operating in a shell casing. • Buoyant shell aerodynamics under varying wind conditions. - Abstract: Wind energy becomes more powerful and consistent with an increase in altitude, therefore, harvesting the wind energy at high altitude results in a naturally restocked source of energy which is cheaper and far more efficient than the conventional wind power system. Airborne wind turbine (AWT), one of the many techniques being employed for this purpose, stands out due to its uninterrupted scheme of energy production. This paper presents the aerodynamic performance of AWT system with NREL Phase IV rotor at an altitude of 400 m. Unsteady simulation of the airborne system has been carried out and variations in the rotor’s torque for a complete revolution are reported and discussed. In order to compare the performance of the shell mounted configuration of Phase IV rotor with its standard test configuration, steady state simulations of the rotor are also conducted under various wind conditions for both configurations. Finally, for stable design of the buoyant airborne system, aerodynamic forces on the shell body are computed and reported.

  11. 45 CFR 310.35 - Under what circumstances would emergency FFP be available for Computerized Tribal IV-D Systems?

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Under what circumstances would emergency FFP be... AND OFFICE AUTOMATION Funding for Computerized Tribal IV-D Systems and Office Automation § 310.35 Under what circumstances would emergency FFP be available for Computerized Tribal IV-D Systems? (a...

  12. 45 CFR 310.25 - What conditions apply to acquisitions of Computerized Tribal IV-D Systems?

    Science.gov (United States)

    2010-10-01

    ... FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES COMPUTERIZED TRIBAL IV-D SYSTEMS AND OFFICE AUTOMATION Funding for Computerized Tribal IV-D Systems and Office Automation § 310.25 What conditions apply to... 45 Public Welfare 2 2010-10-01 2010-10-01 false What conditions apply to acquisitions of...

  13. On social justice: Comparing Paul with Plato, Aristotle and the Stoics

    Directory of Open Access Journals (Sweden)

    Johan Strijdom

    2007-05-01

    Full Text Available n “In search of Paul” (2004 Crossan and Reed argue that Paul’s vision and program were essentially in continuity with Jesus’: both opposed, be it in Galilean villages or Roman cities, an unjust imperial system by means of an alternative project of egalitarian, distributive justice. Although Crossan elsewhere demonstrates the deep roots of this concern in the Jewish tradition, he tends to downplay the importance of Greek contributions in this regard. The purpose of this essay will be to offer, in constant dialogue with Crossan (and Reed, a more refined comparison of social justice in Paul on the one hand and Plato, Aristotle and the Stoics on the other. If Paul tried to establish egalitarian and sharing Christian communities under the Roman empire, how do this vision and program compare and contrast with Plato's hierarchical but communal concept of justice, Aristotle’s distributive notion according to merit, and most importantly the Stoics’ argument of “oikeiosis” (i.e., other-concern by concentrical familiarization with the other? Imagine, say Crossan and Reed (CR hereafter in their recent book on Paul, the following dialogue between ourselves and Paul: Do you think, Paul, that all men are created equal and endowed by their Creator with certain inalienable rights? I am not speaking about all men, but about all Christians. But do you think, Paul, that all people should be Christians? Yes, of course,. And do you think, Paul, that all Christians should be equal with one another?Yes, of course. Then do you think, Paul, that it is God’s will for all people to be equal with one another? Well, let me think about that one for a while and, in the meantime, you think about equality in Christ. (CR 2004:234

  14. A Study on planning of promotion for international collaborative development of Generation IV Nuclear Energy Systems

    International Nuclear Information System (INIS)

    Hee, Chang Moon; Yang, M. S.; Ha, J. J.

    2006-06-01

    Korea has participated in the international collaboration programs for the development of future nuclear energy systems driven by the countries holding advanced nuclear technology and Korea and U. S. have cooperated in the INERI. This study is mainly at developing the plan for participation in the collaborative development of the Gen IV, searching the participation strategy for INERI and the INPRO, and the international cooperation in these programs. Contents and scope of the study for successful achievement are as follows; - Investigation and analysis of international and domestic trends related to advanced nuclear technologies - Development of the plan for collaborative development of the Gen IV and conducting the international cooperation activities - Support for the activities related to I-NERI between Korea and U. S. and conducting the international cooperation - International cooperation activities for the INPRO This study can be useful for planning the research plan and setting up of the strategy of integrating the results of the international collaboration and the domestic R and D results by combining the Gen IV and the domestic R and D in the field of future nuclear technology. Furthermore, this study can contribute to establishing the effective foundation and broadening the cooperation activities not only with the advanced countries for acquisition of the advanced technologies but also with the developing countries for the export of the domestic nuclear energy systems

  15. Fuel research for subcritical and critical GEN-IV systems cooled by heavy liquid metal

    International Nuclear Information System (INIS)

    Sobolev, V.; Verwerft, M.

    2009-01-01

    The participation of the Belgian Nuclear Research Centre SCK-CEN in the worldwide GEN-IV research can be considered as an opportunity. Today's GEN-IV research at SCK-CEN is mainly driven by the interests of the project MYRRHA (Multipurpose hYbrid Research Reactor for High-tech Applications). The main goal of this project is to build at SCK-CEN in Mol a new generation fast spectrum, subcritical, research and materials testing reactor MYRRHA driven by a high-energy proton accelerator. This GEN-IV MTR is cooled by heavy liquid metal (Pb-Bi) and will be used for the ADS concept demonstration, testing and qualification of new fuels, transmutation targets and innovative materials. On the European scale, MYRRHA is integrated in the Euratom FP6 Integrated Project (IP) EUROTRANS (EUROpean research programme for TRANSmutation of high level nuclear waste in an accelerator driven system), as the small-scale experimental machine for transmutation demonstration called XT-ADS. Last but not least, this experimental facility will also demonstrate the technological feasibility of the LFR (Lead-cooled Fast Reactor) GEN-IV concept; in EU the LFR design studies are performed in the framework of the Euratom FP6 ELSY (European Lead-cooled SYstem) project, where SCK-CEN is a partner. Among the research needed to ensure a safe and reliable operation of the MYRRHA/XT ADS reactor, the development and qualification of fuel and cladding materials have been recognized as one of the main key issues to be addressed

  16. Democratic institutions: the spell of Plato and the return to the classics

    OpenAIRE

    Colen, José

    2012-01-01

    The purpose of this paper, that reflects an ongoing research, is to suggest the usefulness of an analysis of the readings of Karl Popper and Leo Strauss on Plato's political philosophy. Very different as they are, both thinkers saw in the Republic one of the most powerful critics of democracy and built interpretations and polemic arguments by contrast with Plato's arguments. There are currently two arguments questioning liberal or constitutional democracy. The first originates in the social s...

  17. The role of the poet in Plato's ideal cities of Callipolis and Magnesia

    OpenAIRE

    Gerard Naddaf

    2008-01-01

    Plato's attitude toward the poets and poetry has always been a flashpoint of debate, controversy and notoriety, but most scholars have failed to see their central role in the ideal cities of the Republic and the Laws, that is, Callipolis and Magnesia. In this paper, I argue that in neither dialogue does Plato "exile" the poets, but, instead, believes they must, like all citizens, exercise the expertise proper to their profession, allowing them the right to become full-fledged participants in ...

  18. Irradiation Alters MMP-2/TIMP-2 System and Collagen Type IV Degradation in Brain

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Won Hee [School of Biomedical Engineering and Sciences, Virginia Polytechnic Institute and State University, Blacksburg, Virginia (United States); Warrington, Junie P.; Sonntag, William E. [Reynolds Oklahoma Center on Aging, Department of Geriatric Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma (United States); Lee, Yong Woo, E-mail: ywlee@vt.edu [School of Biomedical Engineering and Sciences, Virginia Polytechnic Institute and State University, Blacksburg, Virginia (United States); Department of Biomedical Sciences and Pathobiology, Virginia Polytechnic Institute and State University, Blacksburg, Virginia (United States)

    2012-04-01

    Purpose: Blood-brain barrier (BBB) disruption is one of the major consequences of radiation-induced normal tissue injury in the central nervous system. We examined the effects of whole-brain irradiation on matrix metalloproteinases (MMPs)/tissue inhibitors of metalloproteinases (TIMPs) and extracellular matrix (ECM) degradation in the brain. Methods and Materials: Animals received either whole-brain irradiation (a single dose of 10 Gy {gamma}-rays or a fractionated dose of 40 Gy {gamma}-rays, total) or sham-irradiation and were maintained for 4, 8, and 24 h following irradiation. mRNA expression levels of MMPs and TIMPs in the brain were analyzed by real-time reverse transcriptase-polymerase chain reaction (PCR). The functional activity of MMPs was measured by in situ zymography, and degradation of ECM was visualized by collagen type IV immunofluorescent staining. Results: A significant increase in mRNA expression levels of MMP-2, MMP-9, and TIMP-1 was observed in irradiated brains compared to that in sham-irradiated controls. In situ zymography revealed a strong gelatinolytic activity in the brain 24 h postirradiation, and the enhanced gelatinolytic activity mediated by irradiation was significantly attenuated in the presence of anti-MMP-2 antibody. A significant reduction in collagen type IV immunoreactivity was also detected in the brain at 24 h after irradiation. In contrast, the levels of collagen type IV were not significantly changed at 4 and 8 h after irradiation compared with the sham-irradiated controls. Conclusions: The present study demonstrates for the first time that radiation induces an imbalance between MMP-2 and TIMP-2 levels and suggests that degradation of collagen type IV, a major ECM component of BBB basement membrane, may have a role in the pathogenesis of brain injury.

  19. Irradiation Alters MMP-2/TIMP-2 System and Collagen Type IV Degradation in Brain

    International Nuclear Information System (INIS)

    Lee, Won Hee; Warrington, Junie P.; Sonntag, William E.; Lee, Yong Woo

    2012-01-01

    Purpose: Blood-brain barrier (BBB) disruption is one of the major consequences of radiation-induced normal tissue injury in the central nervous system. We examined the effects of whole-brain irradiation on matrix metalloproteinases (MMPs)/tissue inhibitors of metalloproteinases (TIMPs) and extracellular matrix (ECM) degradation in the brain. Methods and Materials: Animals received either whole-brain irradiation (a single dose of 10 Gy γ-rays or a fractionated dose of 40 Gy γ-rays, total) or sham-irradiation and were maintained for 4, 8, and 24 h following irradiation. mRNA expression levels of MMPs and TIMPs in the brain were analyzed by real-time reverse transcriptase-polymerase chain reaction (PCR). The functional activity of MMPs was measured by in situ zymography, and degradation of ECM was visualized by collagen type IV immunofluorescent staining. Results: A significant increase in mRNA expression levels of MMP-2, MMP-9, and TIMP-1 was observed in irradiated brains compared to that in sham-irradiated controls. In situ zymography revealed a strong gelatinolytic activity in the brain 24 h postirradiation, and the enhanced gelatinolytic activity mediated by irradiation was significantly attenuated in the presence of anti-MMP-2 antibody. A significant reduction in collagen type IV immunoreactivity was also detected in the brain at 24 h after irradiation. In contrast, the levels of collagen type IV were not significantly changed at 4 and 8 h after irradiation compared with the sham-irradiated controls. Conclusions: The present study demonstrates for the first time that radiation induces an imbalance between MMP-2 and TIMP-2 levels and suggests that degradation of collagen type IV, a major ECM component of BBB basement membrane, may have a role in the pathogenesis of brain injury.

  20. The Systemic Theory of Living Systems. Part IV: Systemic Medicine—The Praxis

    Directory of Open Access Journals (Sweden)

    José A. Olalde Rangel

    2005-01-01

    Full Text Available This fourth lecture illustrates the praxis and results of Systemic Medicine (SM in various therapeutic applications. SM's success has made it popular throughout Venezuela and Puerto Rico. The treatment of over 300 000 patients by 150 orthodox MD's, trained and qualified in SM, in 35 medical establishments with above average results corroborate its effectiveness as an eCAM in chronic degenerative diseases. Herein we provide a synopsis of results obtained in four such pathologies—the journal's necessary space restrictions somewhat limiting content—as well as clinical and photographic evidence. The validity of any medical theory is substantiated by its degree of effectivity and success. The workability of evidence-based SM corroborates Systemic Theory's transcendence.

  1. Data flow methods for dynamic system simulation - A CSSL-IV microcomputer network interface

    Science.gov (United States)

    Makoui, A.; Karplus, W. J.

    1983-01-01

    A major problem in employing networks of microcomputers for the real-time simulation of complex systems is to allocate computational tasks to the various microcomputers in such a way that idle time and time lost in interprocess communication is minimized. The research reported in this paper is directed to the development of a software interface between a higher-level simulation language and a network of microcomputers. A CSSL-IV source program is translated to a data flow graph. This graph is then analyzed automatically so as to allocate computing tasks to the various processors.

  2. Chaos in periodically forced Holling type IV predator-prey system with impulsive perturbations

    International Nuclear Information System (INIS)

    Zhang Shuwen; Tan Dejun; Chen Lansun

    2006-01-01

    The effect of periodic forcing and impulsive perturbations on predator-prey model with Holling type IV functional response is investigated. The periodic forcing is affected by assuming a periodic variation in the intrinsic growth rate of the prey. The impulsive perturbations are affected by introducing periodic constant impulsive immigration of predator. The dynamical behavior of the system is simulated and bifurcation diagrams are obtained for different parameters. The results show that periodic forcing and impulsive perturbation can easily give rise to complex dynamics, including (1) quasi-periodic oscillating, (2) period doubling cascade, (3) chaos, (4) period halfing cascade

  3. World Energy Data System (WENDS). Volume IV. Country data, SG-YO

    Energy Technology Data Exchange (ETDEWEB)

    None

    1979-06-01

    The World Energy Data System contains organized data on those countries and international organizations that may have critical impact on the world energy scene. Included in this volume, Vol. IV, are Senegal, South Africa, Soviet Union, Spain, Sweden, Switzerland, Taiwan, Tanzania, Thailand, Turkey, United Kingdom, United States, Upper Volta, Venezuela, and Yugoslavia. The following topics are covered for most of the countries: economic, demographic, and educational profiles; energy policy; indigenous energy resources and uses; forecasts, demand, exports, imports of energy supplies; environmental considerations of energy supplies; power production facilities; energy industries; commercial applications of energy; research and development activities of energy; and international activities.

  4. AtlA functions as a peptidoglycan lytic transglycosylase in the Neisseria gonorrhoeae type IV secretion system.

    Science.gov (United States)

    Kohler, Petra L; Hamilton, Holly L; Cloud-Hansen, Karen; Dillard, Joseph P

    2007-08-01

    Type IV secretion systems require peptidoglycan lytic transglycosylases for efficient secretion, but the function of these enzymes is not clear. The type IV secretion system gene cluster of Neisseria gonorrhoeae encodes two peptidoglycan transglycosylase homologues. One, LtgX, is similar to peptidoglycan transglycosylases from other type IV secretion systems. The other, AtlA, is similar to endolysins from bacteriophages and is not similar to any described type IV secretion component. We characterized the enzymatic function of AtlA in order to examine its role in the type IV secretion system. Purified AtlA was found to degrade macromolecular peptidoglycan and to produce 1,6-anhydro peptidoglycan monomers, characteristic of lytic transglycosylase activity. We found that AtlA can functionally replace the lambda endolysin to lyse Escherichia coli. In contrast, a sensitive measure of lysis demonstrated that AtlA does not lyse gonococci expressing it or gonococci cocultured with an AtlA-expressing strain. The gonococcal type IV secretion system secretes DNA during growth. A deletion of ltgX or a substitution in the putative active site of AtlA severely decreased DNA secretion. These results indicate that AtlA and LtgX are actively involved in type IV secretion and that AtlA is not involved in lysis of gonococci to release DNA. This is the first demonstration that a type IV secretion peptidoglycanase has lytic transglycosylase activity. These data show that AtlA plays a role in type IV secretion of DNA that requires peptidoglycan breakdown without cell lysis.

  5. IVS Organization

    Science.gov (United States)

    2004-01-01

    International VLBI Service (IVS) is an international collaboration of organizations which operate or support Very Long Baseline Interferometry (VLBI) components. The goals are: To provide a service to support geodetic, geophysical and astrometric research and operational activities. To promote research and development activities in all aspects of the geodetic and astrometric VLBI technique. To interact with the community of users of VLBI products and to integrate VLBI into a global Earth observing system.

  6. AtlasT4SS: a curated database for type IV secretion systems.

    Science.gov (United States)

    Souza, Rangel C; del Rosario Quispe Saji, Guadalupe; Costa, Maiana O C; Netto, Diogo S; Lima, Nicholas C B; Klein, Cecília C; Vasconcelos, Ana Tereza R; Nicolás, Marisa F

    2012-08-09

    The type IV secretion system (T4SS) can be classified as a large family of macromolecule transporter systems, divided into three recognized sub-families, according to the well-known functions. The major sub-family is the conjugation system, which allows transfer of genetic material, such as a nucleoprotein, via cell contact among bacteria. Also, the conjugation system can transfer genetic material from bacteria to eukaryotic cells; such is the case with the T-DNA transfer of Agrobacterium tumefaciens to host plant cells. The system of effector protein transport constitutes the second sub-family, and the third one corresponds to the DNA uptake/release system. Genome analyses have revealed numerous T4SS in Bacteria and Archaea. The purpose of this work was to organize, classify, and integrate the T4SS data into a single database, called AtlasT4SS - the first public database devoted exclusively to this prokaryotic secretion system. The AtlasT4SS is a manual curated database that describes a large number of proteins related to the type IV secretion system reported so far in Gram-negative and Gram-positive bacteria, as well as in Archaea. The database was created using the RDBMS MySQL and the Catalyst Framework based in the Perl programming language and using the Model-View-Controller (MVC) design pattern for Web. The current version holds a comprehensive collection of 1,617 T4SS proteins from 58 Bacteria (49 Gram-negative and 9 Gram-Positive), one Archaea and 11 plasmids. By applying the bi-directional best hit (BBH) relationship in pairwise genome comparison, it was possible to obtain a core set of 134 clusters of orthologous genes encoding T4SS proteins. In our database we present one way of classifying orthologous groups of T4SSs in a hierarchical classification scheme with three levels. The first level comprises four classes that are based on the organization of genetic determinants, shared homologies, and evolutionary relationships: (i) F-T4SS, (ii) P-T4SS, (iii

  7. The micro-fascism of Plato's good citizen: producing (dis)order through the construction of risk.

    Science.gov (United States)

    O'Byrne, Patrick; Holmes, Dave

    2007-04-01

    The human body has come to be seen as forever susceptible to both external and internal hazards, which in many circumstances require immediate, heroic, and expensive intervention. In response to this, there has been a shift from a treatment-based healthcare model to one of prevention wherein nurses play an integral role by identifying and assessing risks for individuals, communities, and populations. This paper uses Deborah Lupton's outline of the spectrum of risk and applies the theoretical works of Foucault and Plato to demonstrate the means by which nurses maintain social order by identifying and counselling risk takers. It also utilizes the work of Deleuze and Guattari to illustrate how Plato's framework for creating social order through the creation of the good citizen can be viewed as a micro-fascist system, which has been adopted wholeheartedly by preventative health professionals. The goal of this paper is to present an alternate understanding of risk to provide nurses and other healthcare professionals with a non-traditional appreciation of certain aspects of their practice as researchers and clinicians.

  8. Basis for the safety approach for design and assessment of Generation IV nuclear systems

    International Nuclear Information System (INIS)

    Fiorini, G.L.; Leahy, T.

    2009-01-01

    The primary objective of the RSWG is the implementation of a harmonized approach on long-term safety, and to address risk and regulatory issues in development of the next generation of nuclear systems. To this end, the group is proposing safety goals and evaluation methodology applicable for the design and assessment of future systems. The paper resumes the content of the first RSWG report which provides insights for the safety approach and assists the GIF Systems Steering Committee as well as the GIF Experts Group and the GIF Policy Group for the definition of the most adequate safety related Gen IV R and D. The document is also an essential contributor to help identifying the needed supportive crosscut R and D effort (i.e. applicable to all the innovative nuclear technologies). Although the report presents a number of thoughts and recommendations, it really represents only the start of the efforts for the RSWG. (author)

  9. Overall system description and safety characteristics of Prototype Gen IV Sodium Cooled Fast Reactor in Korea

    International Nuclear Information System (INIS)

    Yoo, Jae Woon; Chang, Jin Wook; Lim, Jae Yong; Cheon, Jin Sik; Lee, Tae Ho; Kim, Sung Kyun; Lee, Kwi Lim; Joo, Hyung Kook

    2016-01-01

    The Prototype Gen IV sodium cooled fast reactor (PGSFR) has been developed for the last 4 years, fulfilling the technology demonstration of the burning capability of transuranic elements included in light water reactor spent nuclear fuel. The PGSFR design has been focused on the robustness of safety systems by enhancing inherent safety characteristics of metal fuel and strengthening passive safety features using natural circulation and thermal expansion. The preliminary safety information document as a major outcome of the first design phase of PGSFR development was issued at the end of 2015. The project entered the second design phase at the beginning of 2016. This paper summarizes the overall structures, systems, and components of nuclear steam supply system and safety characteristics of the PGSFR. The research and development activities to demonstrate the safety performance are also briefly introduced in the paper

  10. Overall System Description and Safety Characteristics of Prototype Gen IV Sodium Cooled Fast Reactor in Korea

    Directory of Open Access Journals (Sweden)

    Jaewoon Yoo

    2016-10-01

    Full Text Available The Prototype Gen IV sodium cooled fast reactor (PGSFR has been developed for the last 4 years, fulfilling the technology demonstration of the burning capability of transuranic elements included in light water reactor spent nuclear fuel. The PGSFR design has been focused on the robustness of safety systems by enhancing inherent safety characteristics of metal fuel and strengthening passive safety features using natural circulation and thermal expansion. The preliminary safety information document as a major outcome of the first design phase of PGSFR development was issued at the end of 2015. The project entered the second design phase at the beginning of 2016. This paper summarizes the overall structures, systems, and components of nuclear steam supply system and safety characteristics of the PGSFR. The research and development activities to demonstrate the safety performance are also briefly introduced in the paper.

  11. Systemic Correction of Murine Glycogen Storage Disease Type IV by an AAV-Mediated Gene Therapy.

    Science.gov (United States)

    Yi, Haiqing; Zhang, Quan; Brooks, Elizabeth D; Yang, Chunyu; Thurberg, Beth L; Kishnani, Priya S; Sun, Baodong

    2017-03-01

    Deficiency of glycogen branching enzyme (GBE) causes glycogen storage disease type IV (GSD IV), which is characterized by the accumulation of a less branched, poorly soluble form of glycogen called polyglucosan (PG) in multiple tissues. This study evaluates the efficacy of gene therapy with an adeno-associated viral (AAV) vector in a mouse model of adult form of GSD IV (Gbe1 ys/ys ). An AAV serotype 9 (AAV9) vector containing a human GBE expression cassette (AAV-GBE) was intravenously injected into 14-day-old Gbe1 ys/ys mice at a dose of 5 × 10 11 vector genomes per mouse. Mice were euthanized at 3 and 9 months of age. In the AAV-treated mice at 3 months of age, GBE enzyme activity was highly elevated in heart, which is consistent with the high copy number of the viral vector genome detected. GBE activity also increased significantly in skeletal muscles and the brain, but not in the liver. The glycogen content was reduced to wild-type levels in muscles and significantly reduced in the liver and brain. At 9 months of age, though GBE activity was only significantly elevated in the heart, glycogen levels were significantly reduced in the liver, brain, and skeletal muscles of the AAV-treated mice. In addition, the AAV treatment resulted in an overall decrease in plasma activities of alanine transaminase, aspartate transaminase, and creatine kinase, and a significant increase in fasting plasma glucose concentration at 9 months of age. This suggests an alleviation of damage and improvement of function in the liver and muscles by the AAV treatment. This study demonstrated a long-term benefit of a systemic injection of an AAV-GBE vector in Gbe1 ys/ys mice.

  12. Study on high temperature design methodology of heat-resistant materials for GEN-IV systems

    Energy Technology Data Exchange (ETDEWEB)

    Ryu, Woo Seog; Kim, D. W.; Kim, S. H.; Kim, W. G.; Kim, J. H.; Park, D. G.; Yoon, J. H.; Lee, H. Y.; Hing, J. H

    2005-08-15

    Analysis of the existing high temperature design and assessment codes such as US(ASME-NH,Draft Code Case for Alloy 617), France(RCC-MR), UK(R5), Japan(BDS/DDS/FDS) for Gen IV reactor structure has been carried out. In addition the scope and fields for research and development is needed in the future have been defined. For assessing the high temperature creep cracks, time dependent fracture mechanics (TDFM) parameters of the C and Ct were analyzed. The creep propagation data were obtained from the creep crack growth tests for type 316LN stainless steels, and creep crack growth testing machine for Gen-IV system up to 950 .deg. C was set up. Damage mechanism and causes for creep-fatigue were investigated. The difference between prediction creep-fatigue life and experimental life were investigated. Material properties for analysis creep-fatigue damage were recommended. The assessment procedure (Draft) on creep-fatigue crack initiation has been developed based on the technical appendix A16 of French RCC-MR code. Ultrasonic wave signal against creep ruptured specimens of type 316LN stainless steel was obtained. It was identified that creep damage can be evaluated by ultrasonic method. The NDT techniques evaluated include Barkhausen noise, magnetic hysteresis parameters, positron annihilation, X-ray diffraction and small angle neutron scattering. Experimental procedure and evaluation method of material integrity were developed through the fracture toughness test of Cr-Mo steel.

  13. The role of the poet in Plato's ideal cities of Callipolis and Magnesia

    Directory of Open Access Journals (Sweden)

    Gerard Naddaf

    2008-01-01

    Full Text Available Plato's attitude toward the poets and poetry has always been a flashpoint of debate, controversy and notoriety, but most scholars have failed to see their central role in the ideal cities of the Republic and the Laws, that is, Callipolis and Magnesia. In this paper, I argue that in neither dialogue does Plato "exile" the poets, but, instead, believes they must, like all citizens, exercise the expertise proper to their profession, allowing them the right to become full-fledged participants in the productive class. Moreover, attention to certain details reveals that Plato harnesses both positive and negative factors in poetry to bring his ideal cities closer to a practical realization. The status of the poet and his craft in this context has rarely to my knowledge been addressed.

  14. Plato's Critique of Rhetoric in the "Gorgias" (447a-466a): Epistemology, Methodology, and the Lyotardian Differend.

    Science.gov (United States)

    McComiskey, Bruce

    The uncritical acceptance of Plato's treatment of sophistic doctrines (specifically in Plato's dialogue the "Gorgias") in the university has resulted in an impoverished contemporary view of sophistic rhetoric. Since Socrates' foundational epistemology allows for the knowledge of immutable truth and Gorgias' relativistic epistemology does…

  15. Purification through Emotions: The Role of Shame in Plato's "Sophist" 230B4-E5

    Science.gov (United States)

    Candiotto, Laura

    2018-01-01

    This article proposes an analysis of Plato's "Sophist" (230b4--e5) that underlines the bond between the logical and the emotional components of the Socratic "elenchus", with the aim of depicting the social valence of this philosophical practice. The use of emotions characterizing the 'elenctic' method described by Plato is…

  16. Kinetics of Vinyl Polymerization of Methyl Methacrylate Initiated by Ce(IV-Vanillin Redox System

    Directory of Open Access Journals (Sweden)

    M. Palanivelu

    2012-01-01

    Full Text Available The kinetics of polymerization of methyl methacrylate initiated by Ce(IV-Vanillin redox system was studied in aqueous solution of sulfuric acid at 40°C. The rate of polymerization (Rp and the reaction orders with respect to monomer, initiator and ligand have been determined and found to be 1.5, 0.5 and 0.5 respectively. The effect of concentration of sulfuric acid on the polymerization was also studied. The rate of polymerization was found to increase with increasing temperature 30–60°C and decreases at higher temperature (>60°C. The overall activation energy (Ea was found to be 36.7 kJ/mol. A suitable kinetic scheme has been proposed.

  17. Anomalous isotope effects in the U(IV)-U(VI) exchange system

    International Nuclear Information System (INIS)

    Fujii, Yasuhiko; Nomura, Masao; Okamoto, Makoto; Onitsuka, Hatsuki; Nakanishi, Takashi.

    1992-01-01

    In previous papers, the enrichment of 236 U in the U(IV) - U(VI) chemical exchange system was found to be significantly smaller than the value estimated by the normal mass dependence enrichment of 235 U. Further experiments have been carried out in the present work to confirm the strange phenomenon of the isotopic anomaly in uranium enrichment. The results have indicated that the separation coefficient of 236 U is the same value as one previously reported. To confirm the anomaly of uranium isotope separation, α-ray spectrometry was implemented to check the enrichment behavior of 234 U. Although no theoretical explanation is given for the isotopic anomaly, this is favorable phenomenon for the re-enrichment of recycled uranium which contains isotopes 232 U and 236 U. (author)

  18. A novel chemiluminescence system with diperiodatonickelate (IV) for the determination of adrenaline

    Science.gov (United States)

    Yang, Chunyan; Chen, Fubin; Chang, Ziqiang; Sun, Yonghua; Zhang, Zhujun

    2014-03-01

    A novel chemiluminescence (CL) system with diperiodatonickelate (IV) (DPN) was developed for the determination of adrenaline for the first time. The possible CL emission mechanism was briefly discussed by comparing the fluorescence emission spectra with CL spectra. Under the optimum conditions, the relative CL intensity was linear over the concentration of AD ranging from 1.0 × 10-7 to 1.0 × 10-5 g mL-1 with a detection limit of 4.0 × 10-8 g mL-1 (3σ). And the relative standard deviation was 3.7% for 2.0 × 10-6 g mL-1 AD (n = 11). The developed method has been successfully applied to the determination of AD in pharmaceutical preparations.

  19. Reassessing the role of DotF in the Legionella pneumophila type IV secretion system.

    Directory of Open Access Journals (Sweden)

    Molly C Sutherland

    Full Text Available Legionella pneumophila, the causative agent of a severe pneumonia termed Legionnaires' Disease, survives and replicates within both protozoan hosts and human alveolar macrophages. Intracellular survival is dependent upon secretion of a plethora of protein effectors that function to form a replicative vacuole, evade the endocytic pathway and subvert host immune defenses. Export of these factors requires a type IV secretion system (T4SS called Dot/Icm that is composed of twenty-seven proteins. This report focuses on the DotF protein, which was previously postulated to have several different functions, one of which centered on binding Dot/Icm substrates. In this report, we examined if DotF functions as the T4SS inner membrane receptor for Dot/Icm substrates. Although we were able to recapitulate the previously published bacterial two-hybrid interaction between DotF and several substrates, the interaction was not dependent on the Dot/Icm substrates' signal sequences as predicted for a substrate:receptor interaction. In addition, binding did not require the cytoplasmic domain of DotF, which was anticipated to be involved in recognizing substrates in the cytoplasm. Finally, inactivation of dotF did not abolish intracellular growth of L. pneumophila or translocation of substrates, two phenotypes dependent on the T4SS receptor. These data strongly suggest that DotF does not act as the major receptor for Dot/Icm substrates and therefore likely performs an accessory function within the core-transmembrane subcomplex of the L. pneumophila Dot/Icm type IV secretion system.

  20. Kinetics of a redox reaction in the system Ce(IV) β-diketonate - additional ligand

    International Nuclear Information System (INIS)

    Anufrieva, S.I.; Snezhko, N.I.; Pechurova, N.I.; Martynenko, L.N.; Spitsyn, V.I.

    1982-01-01

    Preparation of solutions containing stable compounds of Ce(IV) with organic ligands is difficult, because even strong Ce(IV) complexes undergo intramolecular reduction and have a tendency to hydrolysis. It is known that Ce(IV) β-diketonates have different resistances to reduction inorganic solvents, depending on the structure. Using spectrophotometric analysis we have investigated the oxidation-reduction characteristics of solutions of certain Ce(IV) β-diketonates in benzene in the absence and presence of neutral ligands containing donor O or N atoms

  1. Methodology for proliferation resistance and physical protection of Generation IV nuclear energy systems

    International Nuclear Information System (INIS)

    Bari, R.; Peterson, P.; Nishimura, R.; Roglans-Ribas, J.

    2005-01-01

    Enhanced proliferation resistance and physical protection (PR and PP) is one of the technology goals for advanced nuclear concepts. Under the auspices of the Generation IV International Forum an international experts group has been chartered to develop an evaluation methodology for PR and PP. This methodology will permit an objective PR and PP comparison between alternative nuclear systems and support design optimization to enhance robustness against proliferation, theft and sabotage. The assessment framework consists of identifying the threats to be considered, defining the PR and PP measures required to evaluate the resistance of a nuclear system to proliferation, theft or sabotage, and establishing quantitative methods to evaluate the proposed measures. The defined PR and PP measures are based on the design of the system (e.g., materials, processes, facilities), and institutional measures (e.g., safeguards, access control). The assessment methodology uses analysis of pathways' with respect to specific threats to determine the PR and PP measures. Analysis requires definition of the threats (i.e. objective, capability, strategy), decomposition of the system into its relevant elements (e.g., reactor core, fuel recycle facility, fuel storage), and identification of targets. (author)

  2. The dynamics of a harvested predator-prey system with Holling type IV functional response.

    Science.gov (United States)

    Liu, Xinxin; Huang, Qingdao

    2018-05-31

    The paper aims to investigate the dynamical behavior of a predator-prey system with Holling type IV functional response in which both the species are subject to capturing. We mainly consider how the harvesting affects equilibria, stability, limit cycles and bifurcations in this system. We adopt the method of qualitative and quantitative analysis, which is based on the dynamical theory, bifurcation theory and numerical simulation. The boundedness of solutions, the existence and stability of equilibrium points of the system are further studied. Based on the Sotomayor's theorem, the existence of transcritical bifurcation and saddle-node bifurcation are derived. We use the normal form theorem to analyze the Hopf bifurcation. Simulation results show that the first Lyapunov coefficient is negative and a stable limit cycle may bifurcate. Numerical simulations are performed to make analytical studies more complete. This work illustrates that using the harvesting effort as control parameter can change the behaviors of the system, which may be useful for the biological management. Copyright © 2018 Elsevier B.V. All rights reserved.

  3. System for the measurement and detection of electric energy losses (SIM-IV); Sistema de medicion y deteccion de perdidas de energia electrica (SIM-IV)

    Energy Technology Data Exchange (ETDEWEB)

    Vidrio L, Gilberto; Gomez L, Martin J; Castan L, Roberto [Instituto de Investigaciones Electricas, Cuernavaca, Morelos (Mexico)

    2004-07-01

    The electric utility companies worldwide suffer, in greater or lesser degree, electrical energy losses. A great percentage of these losses is mostly due to illegal appropriations of energy. The consumers, by means of illicit practices such as clandestine connections and alteration of the operation of electricity meters, carry out the energy robbery. In order to try to alleviate the problematic of electric energy losses, in their majority by illicit, the electric utility companies have implemented one or more actions. Among the most important are: Visual inspection of the metering facilities. Its purpose is to verify the condition of the traditional protections of the metering installations, such as the seals and safety rings. Detection Equipment: These are recorders of energy consumption and of faults in conductors and are used to detect illicit connections and deviations in the consumption patterns and to the electrical energy connection or to the secondary distribution network. Statistical analysis of consumption: Many electric facility companies have adapted their processing consumption reading systems to detect deviations in the of consumption patterns of their clients. This could correspond to abnormal situations. Since this country is not extraneous to the problematic of energy losses, in the Instituto de Investigaciones Electricas it was developed a System of Measurement and Detection of Losses of Electrical Energy (SIM-IV) as a result of the knowledge of the problematic obtained from the projects in the metering area and of the interaction through work meetings with personnel of the Comision Federal de Electricidad and of Luz y Fuerza del Centro (LyFC), in which concepts of advanced technology were applied for the measurement of electrical variables. The SIM-IV is a system oriented to the metering of consumption and the detection of robberies of electrical energy caused by clandestine connections and non-allowed interventions to the energy meters. Since

  4. Nuclear proliferation and civilian nuclear power: report of the Nonproliferation Alternative Systems Assessment Program. Volume IV. Commercial potential

    International Nuclear Information System (INIS)

    1979-12-01

    Volume IV provides time and cost estimates for positioning new nuclear power systems for commercial deployment. The assessment also estimates the rates at which the new systems might penetrate the domestic market, assuming the continuing viability of the massive light-water reactor network that now exists worldwide. This assessment does not recommend specific, detailed program plans and budgets for individual systems; however, it is clear from this analysis that any of the systems investigated could be deployed if dictated by national interest

  5. Vibrio tapetis Displays an Original Type IV Secretion System in Strains Pathogenic for Bivalve Molluscs

    Directory of Open Access Journals (Sweden)

    Graciela M. Dias

    2018-02-01

    Full Text Available The Brown Ring Disease (BRD caused high mortality rates since 1986 in the Manila clam Venerupis philippinarum introduced and cultured in Western Europe from the 1970s. The causative agent of BRD is a Gram-Negative bacterium, Vibrio tapetis, which is also pathogenic to fish. Here we report the first assembly of the complete genome of V. tapetis CECT4600T, together with the genome sequences of 16 additional strains isolated across a broad host and geographic range. Our extensive genome dataset allowed us to describe the pathogen pan- and core genomes and to identify putative virulence factors. The V. tapetis core genome consists of 3,352 genes, including multiple potential virulence factors represented by haemolysins, transcriptional regulators, Type I restriction modification system, GGDEF domain proteins, several conjugative plasmids, and a Type IV secretion system. Future research on the coevolutionary arms race between V. tapetis virulence factors and host resistance mechanisms will improve our understanding of how pathogenicity develops in this emerging pathogen.

  6. Overview of the CEA R and D support to generation IV nuclear energy systems

    International Nuclear Information System (INIS)

    Carre, Frank; Anzieu, Pascal; Billot, Philippe; Brossard, Philippe; Fiorini, Gian-Luigi

    2004-01-01

    As a result of an early technology road-map performed at the end of 2000, the CEA selected a sequenced development of advanced gas cooled high temperature nuclear systems as main focus for its R and D programme on future nuclear energy systems. The selection of this research objectives originates both from the significance of fast neutrons and high temperature for nuclear energy to meet the needs anticipated beyond 2020/2030, and from the significant common R and D pathway that supports both medium term industrial projects and more advanced versions of gas cooled reactors. The first step of the 'Gas Technology Path' aims to support the development of a modular HTR likely to meet international market needs around 2020. The second step is a Very High Temperature Reactor (> 950 deg. C) to efficiently produce, among others, hydrogen though thermo-chemical water splitting or to generate electricity with an efficiency above 50%. The third step of the Path is a Gas Fast Reactor that features a fast-spectrum helium-cooled reactor and closed fuel cycle, with a direct-cycle helium turbine for electricity production and full recycle of actinides. The paper succinctly presents the R and D program launched in 2001 by the CEA with industrial partners on the 'Gas Technology Path', which is destined to become the contribution of France to the development of the VHTR and the GFR within the next phase of the Generation IV Forum

  7. Overview of the CEA R and D support to generation IV nuclear energy systems

    Energy Technology Data Exchange (ETDEWEB)

    Carre, Frank; Anzieu, Pascal; Billot, Philippe; Brossard, Philippe; Fiorini, Gian-Luigi

    2004-07-01

    As a result of an early technology road-map performed at the end of 2000, the CEA selected a sequenced development of advanced gas cooled high temperature nuclear systems as main focus for its R and D programme on future nuclear energy systems. The selection of this research objectives originates both from the significance of fast neutrons and high temperature for nuclear energy to meet the needs anticipated beyond 2020/2030, and from the significant common R and D pathway that supports both medium term industrial projects and more advanced versions of gas cooled reactors. The first step of the 'Gas Technology Path' aims to support the development of a modular HTR likely to meet international market needs around 2020. The second step is a Very High Temperature Reactor (> 950 deg. C) to efficiently produce, among others, hydrogen though thermo-chemical water splitting or to generate electricity with an efficiency above 50%. The third step of the Path is a Gas Fast Reactor that features a fast-spectrum helium-cooled reactor and closed fuel cycle, with a direct-cycle helium turbine for electricity production and full recycle of actinides. The paper succinctly presents the R and D program launched in 2001 by the CEA with industrial partners on the 'Gas Technology Path', which is destined to become the contribution of France to the development of the VHTR and the GFR within the next phase of the Generation IV Forum.

  8. ST-elevation acute coronary syndromes in the Platelet Inhibition and Patient Outcomes (PLATO) trial

    DEFF Research Database (Denmark)

    Armstrong, Paul W; Siha, Hany; Fu, Yuling

    2012-01-01

    Ticagrelor, when compared with clopidogrel, reduced the 12-month risk of vascular death/myocardial infarction and stroke in patients with ST-elevation acute coronary syndromes intended to undergo primary percutaneous coronary intervention in the PLATelet inhibition and patient Outcomes (PLATO...

  9. Genesis 2–3 and Alcibiades's speech in Plato's Symposium : A ...

    African Journals Online (AJOL)

    Genesis 2–3 and Alcibiades's speech in Plato's Symposium : A cultural critical reading. ... Abstract. The purpose of this article is to discuss some basic problems and methodological steps concerning the encounter between Hebrews and Greeks in the Classical period and its impact on the Hellenistic era. The relationship ...

  10. Freud, Plato and Irigaray: A Morpho-Logic of Teaching and Learning

    Science.gov (United States)

    Peers, Chris

    2012-01-01

    This article discusses two well-known texts that respectively describe learning and teaching, drawn from the work of Freud and Plato. These texts are considered in psychoanalytic terms using a methodology drawn from the philosophy of Luce Irigaray. In particular the article addresses Irigaray's approach to the analysis of speech and utterance as a…

  11. From Plato to Erikson: How the War on "Bad Play" Has Impoverished Higher Education

    Science.gov (United States)

    Carnes, Mark C.

    2015-01-01

    For centuries, the titans of educational reform--Plato, Rousseau, Dewey, Piaget, Erikson, Csikszentmihalyi and others--have championed the educational benefits of play. Yet many professors and administrators are boggled by the idea of playing academic games in college. They instantly dismiss faculty initiatives like "Reacting to the…

  12. Can Prior Knowledge Hurt Text Comprehension? An Answer Borrowed from Plato, Aristotle, and Descartes.

    Science.gov (United States)

    Friedman, Lawrence B.

    Taking a philosophical approach based on what Plato, Aristotle, and Descartes said about knowledge, this paper addresses some of the murkiness in the conceptual space surrounding the issue of whether prior knowledge does or does not facilitate text comprehension. Specifically, the paper first develops a non-exhaustive typology of cases in which…

  13. PUFF-IV, Code System to Generate Multigroup Covariance Matrices from ENDF/B-VI Uncertainty Files

    International Nuclear Information System (INIS)

    2007-01-01

    1 - Description of program or function: The PUFF-IV code system processes ENDF/B-VI formatted nuclear cross section covariance data into multigroup covariance matrices. PUFF-IV is the newest release in this series of codes used to process ENDF uncertainty information and to generate the desired multi-group correlation matrix for the evaluation of interest. This version includes corrections and enhancements over previous versions. It is written in Fortran 90 and allows for a more modular design, thus facilitating future upgrades. PUFF-IV enhances support for resonance parameter covariance formats described in the ENDF standard and now handles almost all resonance parameter covariance information in the resolved region, with the exception of the long range covariance sub-subsections. PUFF-IV is normally used in conjunction with an AMPX master library containing group averaged cross section data. Two utility modules are included in this package to facilitate the data interface. The module SMILER allows one to use NJOY generated GENDF files containing group averaged cross section data in conjunction with PUFF-IV. The module COVCOMP allows one to compare two files written in COVERX format. 2 - Methods: Cross section and flux values on a 'super energy grid,' consisting of the union of the required energy group structure and the energy data points in the ENDF/B-V file, are interpolated from the input cross sections and fluxes. Covariance matrices are calculated for this grid and then collapsed to the required group structure. 3 - Restrictions on the complexity of the problem: PUFF-IV cannot process covariance information for energy and angular distributions of secondary particles. PUFF-IV does not process covariance information in Files 34 and 35; nor does it process covariance information in File 40. These new formats will be addressed in a future version of PUFF

  14. SANS study of Th (IV) third phase formation in HNO3 / DHDECMP-n-dodecane system

    International Nuclear Information System (INIS)

    Lohithakshan, K.V.; Aggarwal, S.K.; Aswal, V.K.

    2009-01-01

    Third phase formation taking place during the extraction of Th (IV) from nitric acid medium by DHDECMP in dodecane has been investigated by small angle neutron scattering (SANS) and explained the process with Baxter model. (author)

  15. God as Intellect in the philosophical Theology of Plato, Aristotle and Plotinus.

    Directory of Open Access Journals (Sweden)

    Nadezhda Volkova

    2017-12-01

    Full Text Available The article gives an overview of the main stages in the development of philosophical theology in Plato, Aristotle and Plotinus, as well as its central concept - Active Intellect or God. It is shown, firstly, that Plato was the first who formulated the concept of a One omnibenevolent God. Plato opposed this doctrine to the gods of traditional mythology. In the "Timaeus" talking about the creation of the world, Plato represents God as an artisan, i. e. Demiurge, who arranges the World soul and matter with the help of the numbers. Therefore, God is introduced as an Intellect, because looking at an intelligible paradigm, he created the cosmos as its likeness. Secondly, it was shown that Aristotle made theology demonstrative theoretical knowledge. God as a subject of such knowledge is the pure actuality of thinking. Third, it is shown that Plotinus, continuing the line of Plato and Aristotle, gave philosophical theology a new, much more personal character. Theology for Plotinus is not only an demonstrative knowledge of the omnibenevolent God, but also a personal experience of reunion with him. A special attention in the article is paid for Plotinus' interpretation of the Platonic Demiurge. It is shown that Plotinus first connected the two aspects of the divine, namely the Demiurge-creator and the intelligible paradigm that are described in the "Timaeus," into the single hypostasis of Intellect. The main reason for this assertion was the necessity to postulate the unity of the intellect and the intelligible object as a necessary condition for the possibility of all cognitions. As a result, instead of the traditional idea of the two gods, Plotinus elaborates the doctrine of a single divine Intellect, combining both these aspects.

  16. Some consideration on nuclear power development. Topics aroused by U.S. proposed 'Generation IV Nuclear Power System

    International Nuclear Information System (INIS)

    Wang Chuanying; Chen Shiqi

    2001-01-01

    U.S. proposed 'Generation IV Nuclear Power System' concept. Its origin and proposed goals for it are analyzed; goals are compared with requirements of URD. In particular, discussed issues on nuclear fuel cycle and Non-proliferation. A well-considered nuclear power development plan, paying close attention to international trend and considering comprehensively domestic situation, is expected

  17. Permanence of a predator-prey discrete system with Holling-IV functional response and distributed delays.

    Science.gov (United States)

    Zhang, X; Wu, Z; Zhou, T

    2016-01-01

    A predator-prey discrete-time model with Holling-IV functional response and distributed delays is investigated in this paper. By using the comparison theorem of the difference equation and some analysis technique, some sufficient conditions are obtained for the permanence of the discrete predator-prey system. Two examples are given to illustrate the feasibility of the obtained result.

  18. Aircraft Alerting Systems Standardization Study. Phase IV. Accident Implications on Systems Design.

    Science.gov (United States)

    1982-06-01

    computing and processing to assimilate and process status informa- 5 tion using...provided with capabilities in computing and processing , sensing, interfacing, and controlling and displaying. 17 o Computing and Processing - Algorithms...alerting system to perform a flight status monitor function would require additional sensinq, computing and processing , interfacing, and controlling

  19. Oceanic Area System Improvement Study (OASIS). Volume IV. Caribbean Region Air Traffic Services System Description.

    Science.gov (United States)

    1981-09-01

    OASIS) U Final Report This report i.s one of a set of companion documents which includes the following volumes: Volume I Executive Summary and...Northern Coastal Region of 4 the Directorate of Engineering and Systems (Direccion de Ingenieria y Sistemas ), which is responsible for maintenance of the

  20. MODERATE C IV ABSORBER SYSTEMS REQUIRE 1012 M☉ DARK MATTER HALOS AT z ∼ 2.3: A CROSS-CORRELATION STUDY OF C IV ABSORBER SYSTEMS AND QUASARS IN SDSS-III BOSS DR9

    International Nuclear Information System (INIS)

    Vikas, Shailendra; Wood-Vasey, W. Michael; Lundgren, Britt; Ross, Nicholas P.; Myers, Adam D.; AlSayyad, Yusra; York, Donald G.; Schneider, Donald P.; Brinkmann, J.; Bizyaev, Dmitry; Brewington, Howard; Malanushenko, Elena; Malanushenko, Viktor; Oravetz, Daniel; Pan, Kaike; Snedden, Stephanie; Ge, Jian; Muna, Demitri; Pâris, Isabelle; Petitjean, Patrick

    2013-01-01

    We measure the two-point cross-correlation function of C IV absorber systems and quasars, using spectroscopic data from the Sloan Digital Sky Survey III Baryon Oscillation Spectroscopic Survey (BOSS; Data Release 9). The 19,701 quasars and 6149 C IV ''moderate'' absorbers, 0.28 Å 2 and represent a factor of two increase in sample size over previous investigations. We find a correlation scale length and slope of the redshift-space cross-correlation function of s 0 = 8.46 ± 1.24 Mpc, γ = 1.68 ± 0.19, in the redshift-space range 10 0 = 7.76 ± 2.80 Mpc, γ = 1.74 ± 0.21. We measure the combined quasar and C IV bias to be b QSO b C I V = 8.81 ± 2.28. Using an estimate of b QSO from the quasar auto-correlation function we find b CIV = 2.38 ± 0.62. This b CIV implies that EW > 0.28 Å C IV absorbers at z ∼ 2.3 are typically found in dark matter halos that have masses ≥10 11.3 -10 13.4 M ☉ at that redshift. The complete BOSS sample will triple the number of both quasars and absorption systems and increase the power of this cross-correlation measurement by a factor of two.

  1. Euratom research and training in generation IV systems with emphasis on V/HTR

    International Nuclear Information System (INIS)

    Goethem, G. van; Manolatos, P.; Fuetterer, M.

    2006-01-01

    In this overview paper, the following questions are addressed: (1) What are the challenges facing the European Union nuclear fission research community in the short (today), medium (2010) and long term (2040)? (2) What kind of research and technological development (RTD) does Euratom offer to respond to these challenges, in particular in the area of reactor systems and fuel cycles? In the general debate about energy supply technologies there are challenges of both a scientific and technological (S/T) as well as an economic and political (E/P) nature. Though the Community research programme acts mainly on the former, there is nevertheless important links with Community policy. These not only exist in the specific area of nuclear policy. It is shown in the particular area of nuclear fission, to what extent Euratom research, education and innovation ('Knowledge Triangle: Education, Research, and Innovation') respond to the S/T challenges: (1) sustainability, (2) economics, (3) safety, and (4) proliferation resistance. At the European Commission (EC), the research related to nuclear reactor systems and fuel cycles is principally under the responsibility of the 2 Directorates Generals (DG) DG Research (RTD, located in Brussels), which implements and manages the programme of 'indirect actions', and the DG Joint Research Centre (JRC, headquarters in Brussels and 7 scientific institutes in 5 Member States) which carries out 'direct actions' in their own laboratories. In this HTR-2006 introductory paper, the emphasis is on the indirect and direct actions of the 6 th Euratom research framework programme 2003-2006, FP-6, with special emphasis on V/HTR Generation IV research. (orig.)

  2. Design and application of Mark IV scanning system for radionuclide computed tomography of the brain

    International Nuclear Information System (INIS)

    Kuhl, D.E.; Hoffman, E.J.; Phelps, M.E.; Ricci, A.; Reivich, M.

    1977-01-01

    The MARK IV system was built in our laboratory to provide fast and accurate radionuclide computed tomography (RCT). It is designed primarily for detecting commonly available radioactive labels such as 99 Tcsup(m), but it is also adapted to detecting positron emitters such as 18 F. The system has interlaced convergent collimation in a four-sided arrangement of 32 independent detectors which continuously rotate as a unit, detecting, processing and displaying the reconstructed data while the study progresses. During the scanning procedure, accumulated data are transferred to a digital computer for reconstruction processing. Data are corrected to equalize detector response and compensate for photon attenuation in the head. This program requires 30 seconds for completion, whereupon the final reconstruction, a 64 x 64 matrix from the single revolution, outputs to a core store and is displayed on the screen of a cathode-ray tube. As the rotation sequence continues, new data from each revolution are added to previous data and reprocessed for a new picture. Since the instrument operates at 50 s per revolution, the continuous collection and processing of data causes a new picture to appear on the display every 50 s as the study progresses. The operator may extend or curtail the duration of the examination according to the appearance of the picture. In practice, a five revolution (4.2 min.) scan is commonly used in most clinical studies. The instrument is a high sensitivity device with approximately uniform resolution (1.7 cm FWHM) throughout the section plane. Quantification of concentration of radioactivity in small regions is accurate and reproducible. The instrument has been applied to the study of alterations in cerebral vascular permeability, blood flow and blood volume, and to the study of cerebral glucose metabolism and cerebral spinal fluid distribution. (author)

  3. System for the measurement and detection of electric energy losses (SIM-IV); Sistema de medicion y deteccion de perdidas de energia electrica (SIM-IV)

    Energy Technology Data Exchange (ETDEWEB)

    Vidrio L, Gilberto; Gomez L, Martin J; Castan L, Roberto [Instituto de Investigaciones Electricas, Cuernavaca, Morelos (Mexico)

    2004-07-01

    The electric utility companies worldwide suffer, in greater or lesser degree, electrical energy losses. A great percentage of these losses is mostly due to illegal appropriations of energy. The consumers, by means of illicit practices such as clandestine connections and alteration of the operation of electricity meters, carry out the energy robbery. In order to try to alleviate the problematic of electric energy losses, in their majority by illicit, the electric utility companies have implemented one or more actions. Among the most important are: Visual inspection of the metering facilities. Its purpose is to verify the condition of the traditional protections of the metering installations, such as the seals and safety rings. Detection Equipment: These are recorders of energy consumption and of faults in conductors and are used to detect illicit connections and deviations in the consumption patterns and to the electrical energy connection or to the secondary distribution network. Statistical analysis of consumption: Many electric facility companies have adapted their processing consumption reading systems to detect deviations in the of consumption patterns of their clients. This could correspond to abnormal situations. Since this country is not extraneous to the problematic of energy losses, in the Instituto de Investigaciones Electricas it was developed a System of Measurement and Detection of Losses of Electrical Energy (SIM-IV) as a result of the knowledge of the problematic obtained from the projects in the metering area and of the interaction through work meetings with personnel of the Comision Federal de Electricidad and of Luz y Fuerza del Centro (LyFC), in which concepts of advanced technology were applied for the measurement of electrical variables. The SIM-IV is a system oriented to the metering of consumption and the detection of robberies of electrical energy caused by clandestine connections and non-allowed interventions to the energy meters. Since

  4. Thermodynamic properties of actinide complexes. Part 5: Uranyl(VI)-thioglycolate system; thorium(IV)-glycolate and -thioglycolate systems

    Energy Technology Data Exchange (ETDEWEB)

    di Bernardo, P; Roncari, E; Mazzi, U; Bettella, F [Padua Univ. (Italy). Istituto di Chimica Generale ed Inorganica; Consiglio Nazionale delle Ricerche, Padua (Italy). Lab. di Chimica e Tecnologia dei Radioelementi); Magon, L [Ferrara Univ. (Italy). Istituto Chimico

    1978-04-01

    The changes in free energy, enthalpy and entropy for the formation of uranyl(VI)-thioglycolate, thorium(IV)-glycolate and -thioglycolate complexes have been determined. The changes in free energy were calculated from the stability constants obtained from a potentiometric determination of the concentration of free hydrogen ion, using a glass or quinhydrone electrode. The enthalpy values were measured calorimetrically. The measurements were performed at 25.0/sup 0/C in an aqueous sodium perchlorate medium with the total sodium concentration equal to 100 M. A comparison of the magnitude of the enthalpy and entropy changes for the various systems gives additional support of the view that the thioglycolate acts as a monodentate ligand while the glycolate forms chelate rings.

  5. The Trw type IV secretion system of Bartonella mediates host-specific adhesion to erythrocytes.

    Directory of Open Access Journals (Sweden)

    Muriel Vayssier-Taussat

    2010-06-01

    Full Text Available Bacterial pathogens typically infect only a limited range of hosts; however, the genetic mechanisms governing host-specificity are poorly understood. The alpha-proteobacterial genus Bartonella comprises 21 species that cause host-specific intraerythrocytic bacteremia as hallmark of infection in their respective mammalian reservoirs, including the human-specific pathogens Bartonella quintana and Bartonella bacilliformis that cause trench fever and Oroya fever, respectively. Here, we have identified bacterial factors that mediate host-specific erythrocyte colonization in the mammalian reservoirs. Using mouse-specific Bartonella birtlesii, human-specific Bartonella quintana, cat-specific Bartonella henselae and rat-specific Bartonella tribocorum, we established in vitro adhesion and invasion assays with isolated erythrocytes that fully reproduce the host-specificity of erythrocyte infection as observed in vivo. By signature-tagged mutagenesis of B. birtlesii and mutant selection in a mouse infection model we identified mutants impaired in establishing intraerythrocytic bacteremia. Among 45 abacteremic mutants, five failed to adhere to and invade mouse erythrocytes in vitro. The corresponding genes encode components of the type IV secretion system (T4SS Trw, demonstrating that this virulence factor laterally acquired by the Bartonella lineage is directly involved in adherence to erythrocytes. Strikingly, ectopic expression of Trw of rat-specific B. tribocorum in cat-specific B. henselae or human-specific B. quintana expanded their host range for erythrocyte infection to rat, demonstrating that Trw mediates host-specific erythrocyte infection. A molecular evolutionary analysis of the trw locus further indicated that the variable, surface-located TrwL and TrwJ might represent the T4SS components that determine host-specificity of erythrocyte parasitism. In conclusion, we show that the laterally acquired Trw T4SS diversified in the Bartonella lineage

  6. Plato crater, first observative session: not any "hook" but a shark fin? (Italian Title: La 1° Campagna Osservativa del cratere Plato: non un "uncino" ma una "pinna di squalo"?)

    Science.gov (United States)

    Mercatali, A.

    2018-01-01

    On 1st March 2012 an observative session of Moon's Plato crater was made. The purpose of these observations was to check the presence of one shadow with "hook" form at the inner of Plato crater already reported by H. Percy Wilkins, 3th April 21:30 UT, 1952. The results obtained by us have not shown any shadow with an hook form, but a shadow like a shark fin.

  7. The use of IV-tubing as a closed-suction drainage system during neurosurgical cases in Tanzania.

    Science.gov (United States)

    Bonfield, Christopher M; Shabani, Hamisi K; Kanumba, Emmanuel S; Ellegala, Dilantha B; Nicholas, Joyce

    2013-01-01

    Commercial closed-suctions drainage systems are commonly used in the United States and many other countries for use in neurosurgical cases. However, in Tanzania and other developing nations with fewer resources, these are not available. This report explores another option for a closed-system drainage system utilizing inexpensive supplies found commonly in hospitals around the world. Sterile IV-tubing is cut, inserted into the wound, and brought out through an adjacent puncture incision. For suction, an empty plastic bottle can be attached to the tubing. The IV-tubing closed-suction drainage system was applied in both cranial and spinal neurosurgical procedures, including as subdural, subgaleal, epidural, and suprafacial drains. It maintained suction and was an adequate substitute when commercial drains are unavailable. This report illustrates how sterile IV-tubing can be adapted for use as a closed-drainage system. It utilizes inexpensive supplies commonly found in many hospitals throughout the world and can be applied to both cranial and spinal neurosurgical procedures.

  8. Study of electrolytic reduction of uranium VI to uranium IV in nitrate systems

    Energy Technology Data Exchange (ETDEWEB)

    Araujo, B.F. de; Almeida, S.G. de; Forbicini, S; Matsuda, H T; Araujo, J.A. de [Instituto de Pesquisas Energeticas e Nucleares, Sao Paulo (Brazil). Centro de Engenharia Quimica

    1980-01-01

    Experimental parameters are optimized in order to obtain uranium (IV) nitrate solutions at maximum yield, using hydrazine as stabilizer. Uranium (VI) electrolytic reduction was chosen because: there is no increase in the volume of radioactive effluents; there are no secondary reactions; there is no need for further separations; all reagents used are not inflammable. The method is, therefore, efficient and of low cost.

  9. 75 FR 8508 - Computerized Tribal IV-D Systems and Office Automation

    Science.gov (United States)

    2010-02-25

    ... operating comprehensive Tribal Child Support Enforcement programs under Title IV-D of the Social Security... security and privacy safeguarding requirements reflects our position that security and privacy of child... DEPARTMENT OF HEALTH AND HUMAN SERVICES Administration for Children and Families 45 CFR Parts 309...

  10. The validity of the DSM-IV diagnostic classification system of non-affective psychoses

    NARCIS (Netherlands)

    Korver-Nieberg, Nikie; Quee, Piotr J.; Boos, Heleen B.; Simons, Claudia J.; Kahn, René S.; Cahn, Wiepke; Linszen, Don H.; de Haan, Lieuwe; van Os, Jim; Krabbendam, Lydia; Myin-Germeys, Inez; Wiersma, Durk; Bruggeman, Richard; van den Berg, S. E.; Schroeder, C. L. A.; van der Valk, R.; Dekker, N. [=Nienke; Meijer, C. J.; Korver, N.; Boyette, L. N.; Meijer, J.; van Dam, D.; de Rijke, I.; Huinink, S.; de Vries, R. J.; Jansen, M.; Bos, D.; Hoen, W. P.; te West, E. M.; Groeneveld, S. H. J.; Vergunst, E. M.; Swets, M.; Vothknecht, S.; Poleacov, I.; van Dijk, D.; de Metz, S.; Hasty, M. T.; Geertsa, G.; de Baaij, P. M.; Metzger, A.; van Beveren, N. J. M.; Baldini, M.; Grimbergen, F. D.; Boerma, M. A. M.; van der Werf, M.; Habets, P.; Derks, E. M.; van Leeuwen, M.; Verweij, K.; van Wijk, M.

    2011-01-01

    The schizophrenia and other non-affective disorders categories listed in the DSM-IV, are currently under revision for the development of the fifth edition. The aim of the present study is to demonstrate the validity of these categories by investigating possible differences between diagnostic patient

  11. Title IV Quality Control Project, Stage II. Management Option II: Delivery System Quality Improvements.

    Science.gov (United States)

    Advanced Technology, Inc., Reston, VA.

    Stage Two of the Title IV Quality Control Project is an integrated study of quality in five related Federal financial aid programs for postsecondary students. Section 1 of the paper establishes a framework for defining quality improvements, in order to identify the types of changes that would tend to improve quality across all facets of the…

  12. The validity of the DSM-IV diagnostic classification system of non-affective psychoses

    NARCIS (Netherlands)

    Korver-Nieberg, Nikie; Quee, Piotr J.; Boos, Heleen B.; Simons, Claudia J.

    2011-01-01

    Objective: The schizophrenia and other non-affective disorders categories listed in the DSM-IV, are currently under revision for the development of the fifth edition. The aim of the present study is to demonstrate the validity of these categories by investigating possible differences between

  13. Structure of the type IV secretion system in different strains of Anaplasma phagocytophilum

    Directory of Open Access Journals (Sweden)

    Al-Khedery Basima

    2012-11-01

    Full Text Available Abstract Background Anaplasma phagocytophilum is an intracellular organism in the Order Rickettsiales that infects diverse animal species and is causing an emerging disease in humans, dogs and horses. Different strains have very different cell tropisms and virulence. For example, in the U.S., strains have been described that infect ruminants but not dogs or rodents. An intriguing question is how the strains of A. phagocytophilum differ and what different genome loci are involved in cell tropisms and/or virulence. Type IV secretion systems (T4SS are responsible for translocation of substrates across the cell membrane by mechanisms that require contact with the recipient cell. They are especially important in organisms such as the Rickettsiales which require T4SS to aid colonization and survival within both mammalian and tick vector cells. We determined the structure of the T4SS in 7 strains from the U.S. and Europe and revised the sequence of the repetitive virB6 locus of the human HZ strain. Results Although in all strains the T4SS conforms to the previously described split loci for vir genes, there is great diversity within these loci among strains. This is particularly evident in the virB2 and virB6 which are postulated to encode the secretion channel and proteins exposed on the bacterial surface. VirB6-4 has an unusual highly repetitive structure and can have a molecular weight greater than 500,000. For many of the virs, phylogenetic trees position A. phagocytophilum strains infecting ruminants in the U.S. and Europe distant from strains infecting humans and dogs in the U.S. Conclusions Our study reveals evidence of gene duplication and considerable diversity of T4SS components in strains infecting different animals. The diversity in virB2 is in both the total number of copies, which varied from 8 to 15 in the herein characterized strains, and in the sequence of each copy. The diversity in virB6 is in the sequence of each of the 4 copies in

  14. One aspect of the methodology of cognition in Plato and Dionysius the Areopagite

    Directory of Open Access Journals (Sweden)

    Moiseev, Petr

    2008-06-01

    Full Text Available Petr Moiseev (Perm State Institute of Arts and Cultureshows how the concept of ascension to truth, first formulated by Plato, was later reworked and reevaluated in new cognitive context by such later thinkers, as Plutarch, Iamblichus and, finally, Pseudo-Dionysius the Areopagite. Special attention is given to the concept of knowledge beyond human cognition and the role symbolism played in the process of its development.

  15. Los platos de los peces y el más allá

    OpenAIRE

    Aranegui Gascó, Carmen

    1996-01-01

    - Interpretación de la decoración de los platos de peces ibéticos como expresión de una determinada concepción del orden del universo y del tránsito a la otra vida. Flores, estrellas y espirales son la expresion de los tres elementos, mientras que el pez muestra el camino hacia el más allá.

  16. [History and reception of the translations of Plato's Dialogues by Antoni Bronikowski].

    Science.gov (United States)

    Mróz, Tomasz

    2014-01-01

    The article presents the history of translations of Plato's dialogues as made by A. Bronikowski (1817-1884), their assessment formulated by the contemporary for the translator recipients and today's opinions on them. Bronikowski began his translation work on the legacy of Plato in the '50s of the 19th century and carried them out systematically, despite the many adversities, until his death. The article presents the most important criticisms of the reviewers of Bronikowski's translations, which focused on the flaws of his style. The critics pointed out numerous shortcomings, archaisms, which hindered and prevented smooth reading of the text by readers unfamiliar with the language of the original. Most of the criticisms came from the Warsaw environment, especially from K. Kozłowski, the son of the first Polish translator of Plato, FA. Kozłowski. Among the defenders of Bronikowski there were K. Libelt and J.I. Kraszewski. They raised the subject of difficulty which the translator had to deal with and the lack of literary taste of the audience. It seems that both parties were partially right. Bronikowski's text was indeed not suitable for smooth reading in many places, however, it could serve as a useful tool for students who acquainted themselves with the Greek originals of the dialogues.

  17. A system for customer feedback: the InterVention (IV) Line.

    Science.gov (United States)

    Wood, K E; Barker, J R; Stump, J W

    2001-01-01

    Healthcare organizations use a number of data collection methodologies to identify opportunities for improving customer satisfaction. One methodology used at the 665-bed University Hospitals and Clinics of the University of Mississippi Medical Center is a customer service telephone hotline. Patients, visitors, and staff members call in their compliments and concerns to the InterVention (IV) Line, which provides customized problem solving. This article provides an overview of the customer hotline and presents lessons learned from its implementation.

  18. Asteroids IV

    Science.gov (United States)

    Michel, Patrick; DeMeo, Francesca E.; Bottke, William F.

    Asteroids are fascinating worlds. Considered the building blocks of our planets, many of the authors of this book have devoted their scientific careers to exploring them with the tools of our trade: ground- and spacebased observations, in situ space missions, and studies that run the gamut from theoretical modeling efforts to laboratory work. Like fossils for paleontologists, or DNA for geneticists, they allow us to construct a veritable time machine and provide us with tantalizing glimpses of the earliest nature of our solar system. By investigating them, we can probe what our home system was like before life or even the planets existed. The origin and evolution of life on our planet is also intertwined with asteroids in a different way. It is believed that impacts on the primordial Earth may have delivered the basic components for life, with biology favoring attributes that could more easily survive the aftermath of such energetic events. In this fashion, asteroids may have banished many probable avenues for life to relative obscurity. Similarly, they may have also prevented our biosphere from becoming more complex until more recent eras. The full tale of asteroid impacts on the history of our world, and how human life managed to emerge from myriad possibilities, has yet to be fully told. The hazard posed by asteroid impacts to our civilization is low but singular. The design of efficient mitigation strategies strongly relies on asteroid detection by our ground- and spacebased surveys as well as knowledge of their physical properties. A more positive motivation for asteroid discovery is that the proximity of some asteroids to Earth may allow future astronauts to harvest their water and rare mineral resources for use in exploration. A key goal of asteroid science is therefore to learn how humans and robotic probes can interact with asteroids (and extract their materials) in an efficient way. We expect that these adventures may be commonplace in the future

  19. DNA Delivery and Genomic Integration into Mammalian Target Cells through Type IV A and B Secretion Systems of Human Pathogens

    Directory of Open Access Journals (Sweden)

    Dolores L. Guzmán-Herrador

    2017-08-01

    Full Text Available We explore the potential of bacterial secretion systems as tools for genomic modification of human cells. We previously showed that foreign DNA can be introduced into human cells through the Type IV A secretion system of the human pathogen Bartonella henselae. Moreover, the DNA is delivered covalently attached to the conjugative relaxase TrwC, which promotes its integration into the recipient genome. In this work, we report that this tool can be adapted to other target cells by using different relaxases and secretion systems. The promiscuous relaxase MobA from plasmid RSF1010 can be used to deliver DNA into human cells with higher efficiency than TrwC. MobA also promotes DNA integration, albeit at lower rates than TrwC. Notably, we report that DNA transfer to human cells can also take place through the Type IV secretion system of two intracellular human pathogens, Legionella pneumophila and Coxiella burnetii, which code for a distantly related Dot/Icm Type IV B secretion system. This suggests that DNA transfer could be an intrinsic ability of this family of secretion systems, expanding the range of target human cells. Further analysis of the DNA transfer process showed that recruitment of MobA by Dot/Icm was dependent on the IcmSW chaperone, which may explain the higher DNA transfer rates obtained. Finally, we observed that the presence of MobA negatively affected the intracellular replication of C. burnetii, suggesting an interference with Dot/Icm translocation of virulence factors.

  20. Generation IV Nuclear Energy Systems Construction Cost Reductions through the Use of Virtual Environments - Task 5 Report: Generation IV Reactor Virtual Mockup Proof-of-Principle Study

    International Nuclear Information System (INIS)

    Timothy Shaw; Anthony Baratta; Vaughn Whisker

    2005-01-01

    Task 5 report is part of a 3 year DOE NERI-sponsored effort evaluating immersive virtual reality (CAVE) technology for design review, construction planning, and maintenance planning and training for next generation nuclear power plants. Program covers development of full-scale virtual mockups generated from 3D CAD data presented in a CAVE visualization facility. Created a virtual mockup of PBMR reactor cavity and discussed applications of virtual mockup technology to improve Gen IV design review, construction planning, and maintenance planning

  1. Generation IV Nuclear Energy Systems Construction Cost Reductions through the Use of Virtual Environments - Task 5 Report: Generation IV Reactor Virtual Mockup Proof-of-Principle Study

    Energy Technology Data Exchange (ETDEWEB)

    Timothy Shaw; Anthony Baratta; Vaughn Whisker

    2005-02-28

    Task 5 report is part of a 3 year DOE NERI-sponsored effort evaluating immersive virtual reality (CAVE) technology for design review, construction planning, and maintenance planning and training for next generation nuclear power plants. Program covers development of full-scale virtual mockups generated from 3D CAD data presented in a CAVE visualization facility. Created a virtual mockup of PBMR reactor cavity and discussed applications of virtual mockup technology to improve Gen IV design review, construction planning, and maintenance planning.

  2. Generation IV Nuclear Energy Systems Construction Cost Reductions through the Use of Virtual Environments - Final Report

    International Nuclear Information System (INIS)

    Timothy Shaw; Anthony Baratta; Vaughn Whisker

    2005-01-01

    Final report of 3 year DOE NERI-sponsored effort evaluating immersive virtual reality (CAVE) technology for design review, construction planning, and maintenance planning and training for next generation nuclear power plants. Program covers development of full-scale virtual mockups generated from 3D CAD data presented in a CAVE visualization facility. Mockups applied to design review of AP600/1000, Construction planning for AP 600, and AP 1000 maintenance evaluation. Proof of concept study also performed for GenIV PBMR models

  3. Generation IV Nuclear Energy Systems Construction Cost Reductions through the Use of Virtual Environments - Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Timothy Shaw; Anthony Baratta; Vaughn Whisker

    2005-02-28

    Final report of 3 year DOE NERI-sponsored effort evaluating immersive virtual reality (CAVE) technology for design review, construction planning, and maintenance planning and training for next generation nuclear power plants. Program covers development of full-scale virtual mockups generated from 3D CAD data presented in a CAVE visualization facility. Mockups applied to design review of AP600/1000, Construction planning for AP 600, and AP 1000 maintenance evaluation. Proof of concept study also performed for GenIV PBMR models.

  4. Mechanisms Governing the Creep Behavior of High Temperature Alloys for Generation IV Nuclear Energy Systems

    International Nuclear Information System (INIS)

    Vasudevan, Vijay; Carroll, Laura; Sham, Sam

    2015-01-01

    This research project, which includes collaborators from INL and ORNL, focuses on the study of alloy 617 and alloy 800H that are candidates for applications as intermediate heat exchangers in GEN IV nuclear reactors, with an emphasis on the effects of grain size, grain boundaries and second phases on the creep properties; the mechanisms of dislocation creep, diffusional creep and cavitation; the onset of tertiary creep; and theoretical modeling for long-term predictions of materials behavior and for high temperature alloy design.

  5. Mechanisms Governing the Creep Behavior of High Temperature Alloys for Generation IV Nuclear Energy Systems

    Energy Technology Data Exchange (ETDEWEB)

    Vasudevan, Vijay [Univ. of Cincinnati, OH (United States); Carroll, Laura [Idaho National Lab. (INL), Idaho Falls, ID (United States); Sham, Sam [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2015-04-06

    This research project, which includes collaborators from INL and ORNL, focuses on the study of alloy 617 and alloy 800H that are candidates for applications as intermediate heat exchangers in GEN IV nuclear reactors, with an emphasis on the effects of grain size, grain boundaries and second phases on the creep properties; the mechanisms of dislocation creep, diffusional creep and cavitation; the onset of tertiary creep; and theoretical modeling for long-term predictions of materials behavior and for high temperature alloy design.

  6. Comparative kinetic and equilibrium investigations on the extraction of U(IV) in nitric acid/Tbp or TLA-Kerosene systems

    Energy Technology Data Exchange (ETDEWEB)

    Daoud, J A; Khalifa, S M; Abdel Rahman, N; Aly, H F [Hot laboratories center, Atomic energy authority post code 13758, (Egypt)

    1995-10-01

    The extraction equilibrium of U(IV) by tributyl-phosphate (Tbp) or trilaurylamine (TLA) in kerosene from nitric acid media was investigated. The effect of the different parameters affecting the extraction was separately studied and compared. The kinetics of extraction of U(IV) by Tbp or TLA was also investigated using a stirred lewis cell. The data showed that the rate of extraction of U(IV) by Tbp is controlled by chemical reactions at the interface. In the TLA system, the extraction of U(IV) is controlled by chemical reactions at the interface and bulk phase. Rate equations show that the extraction of U(IV) is first order dependent on Tbp concentration while it is of fractional negative order with respect to TLA. The effect of temperature on the rate of extraction was also studied and the thermodynamic functions were evaluated for the two systems. 5 figs.

  7. Innovative materials for GEN IV systems and transmutation facilities (cross-cutting research project GETMAT)

    International Nuclear Information System (INIS)

    Fazio, Concetta; Rieth, Michael; Gomez Briceno, Dolores; Gessi, Alessandro; Henry, Jean; Malerba, Lorenzo

    2010-01-01

    The objectives of the 'Generation IV and Transmutation Materials' (GETMAT) project is to contribute to the development, qualification and ranking of different types of ODS steels and to qualify Ferritic/Martensitic steels in a wide irradiation condition range. The experimental approach is complemented by the development of physical models with the aim to understand and improve the predictability of the materials performance. The GETMAT consortium is composed of fourteen Research centres, nine Universities and one Utility, from eleven European countries. The R and D tasks address (i) the materials availability, fabricability, weldability and their fundamental mechanical properties, (ii) their compatibility with aggressive coolants and development of corrosion protection methods; (iii) their performance under neutron irradiation, and (iv) starting from model alloys relevant for the two classes of alloys, the development and validation of physical models. The exploitation of results to potential end-users will occur through the 'GETMAT User Group', where exchange of information with the nuclear and steel industries, international (outside Europe) Research Organisations and engineers involved in the design of the new reactors, will occur. The exploitation of results to potential end-users will occur through the G ETMAT User Group , where exchange of information with the nuclear and steel industries, international (outside Europe) Research Organisations and engineers involved in the design of the new reactors, will occur

  8. Basic research in support of innovative fuels design for the Generation IV systems (F-BRIDGE project)

    International Nuclear Information System (INIS)

    Valot, Carole; Bertolus, Marjorie; Konings, Rudy; Somers, Joe; Groot, Sander de

    2010-01-01

    F-BRIDGE (Basic Research in support of Innovative Fuels Design for the GEN IV systems) is a 4-year project which started in 2008. It seeks to bridge the gap between basic research and technological applications for generation IV nuclear reactor systems. One of the challenges for the next generation of reactors is to significantly increase the efficiency in designing innovative fuels. The object of the F-BRIDGE project is to complement the empirical approach by a physically-based description of fuel and cladding materials to enable a rationalization of the design process and a better selection of promising fuel systems. Advanced modelling and separate effects experiments are carried out in order to obtain more exact physical descriptions of ceramic fuels and cladding, at relevant scales from the atomic to the macroscopic scale. Research is also focused on assessing and improving 'sphere-pac' fuel, a composite-ceramics concept which has shown promise. The project activities can be broken down into four main areas: (i) Basic research investigations using a multi-scale approach in both experimentation and modelling to enable the generation of missing basic data, the identification of relevant mechanisms and the development of appropriate models; (ii) Transfer between technological issues and basic research by bringing together within the same project materials scientists, engineers and end-users; (iii) Assessment of the drawbacks and benefits of the sphere-pac fuel application to various Generation IV systems; (iv) Education and training to promote research in the field of fuel materials, to ensure the exchange of results and ideas among the participants and to link the project with other related European or international initiatives. The project relies on the complementary expertise of 19 partners: nuclear and non nuclear research organisations, universities, a nuclear engineering company, as well as technology and project management consultancy small and medium

  9. Analysis of piping systems by finite element method using code SAP-IV

    International Nuclear Information System (INIS)

    Cizelj, L.; Ogrizek, D.

    1987-01-01

    Due to extensive and multiple use of the computer code SAP-IV we have decided to install it on VAX 11/750 machine. Installation required a large quantity of programming due to great discrepancies between the CDC (the original program version) and the VAX. Testing was performed basically in the field of pipe elements, based on a comparison between results obtained with the codes PSAFE2, DOCIJEV, PIPESD and SAP -V. Besides, the model of reactor pressure vessel with 3-D thick shell elements was done. The capabilities show good agreement with the results of other programs mentioned above. Along with the package installation, the graphical postprocessors being developed for mesh plotting. (author)

  10. DESIGN AND LAYOUT CONCEPTS FOR COMPACT, FACTORY-PRODUCED, TRANSPORTABLE, GENERATION IV REACTOR SYSTEMS

    Energy Technology Data Exchange (ETDEWEB)

    Mynatt Fred R.; Townsend, L.W.; Williamson, Martin; Williams, Wesley; Miller, Laurence W.; Khan, M. Khurram; McConn, Joe; Kadak, Andrew C.; Berte, Marc V.; Sawhney, Rapinder; Fife, Jacob; Sedler, Todd L.; Conway, Larry E.; Felde, Dave K.

    2003-11-12

    The purpose of this research project is to develop compact (100 to 400 MWe) Generation IV nuclear power plant design and layout concepts that maximize the benefits of factory-based fabrication and optimal packaging, transportation and siting. The reactor concepts selected were compact designs under development in the 2000 to 2001 period. This interdisciplinary project was comprised of three university-led nuclear engineering teams identified by reactor coolant type (water, gas, and liquid metal) and a fourth Industrial Engineering team. The reactors included a Modular Pebble Bed helium-cooled concept being developed at MIT, the IRIS water-cooled concept being developed by a team led by Westinghouse Electric Company, and a Lead-Bismuth-cooled concept developed by UT. In addition to the design and layout concepts this report includes a section on heat exchanger manufacturing simulations and a section on construction and cost impacts of proposed modular designs.

  11. ROSA-IV Large Scale Test Facility (LSTF) system description for second simulated fuel assembly

    International Nuclear Information System (INIS)

    1990-10-01

    The ROSA-IV Program's Large Scale Test Facility (LSTF) is a test facility for integral simulation of thermal-hydraulic response of a pressurized water reactor (PWR) during small break loss-of-coolant accidents (LOCAs) and transients. In this facility, the PWR core nuclear fuel rods are simulated using electric heater rods. The simulated fuel assembly which was installed during the facility construction was replaced with a new one in 1988. The first test with this second simulated fuel assembly was conducted in December 1988. This report describes the facility configuration and characteristics as of this date (December 1988) including the new simulated fuel assembly design and the facility changes which were made during the testing with the first assembly as well as during the renewal of the simulated fuel assembly. (author)

  12. DESIGN AND LAYOUT CONCEPTS FOR COMPACT, FACTORY-PRODUCED, TRANSPORTABLE, GENERATION IV REACTOR SYSTEMS

    International Nuclear Information System (INIS)

    Mynatt, Fred R.; Townsend, L.W.; Williamson, Martin; Williams, Wesley; Miller, Laurence W.; Khan, M. Khurram; McConn, Joe; Kadak, Andrew C.; Berte, Marc V.; Sawhney, Rapinder; Fife, Jacob; Sedler, Todd L.; Conway, Larry E.; Felde, Dave K.

    2003-01-01

    The purpose of this research project is to develop compact (100 to 400 MWe) Generation IV nuclear power plant design and layout concepts that maximize the benefits of factory-based fabrication and optimal packaging, transportation and siting. The reactor concepts selected were compact designs under development in the 2000 to 2001 period. This interdisciplinary project was comprised of three university-led nuclear engineering teams identified by reactor coolant type (water, gas, and liquid metal) and a fourth Industrial Engineering team. The reactors included a Modular Pebble Bed helium-cooled concept being developed at MIT, the IRIS water-cooled concept being developed by a team led by Westinghouse Electric Company, and a Lead-Bismuth-cooled concept developed by UT. In addition to the design and layout concepts this report includes a section on heat exchanger manufacturing simulations and a section on construction and cost impacts of proposed modular designs

  13. A dialogical exploration of the grey zone of health and illness: medical science, anthropology, and Plato on alcohol consumption.

    Science.gov (United States)

    Bonner, Kieran

    2009-01-01

    This paper takes a phenomenological hermeneutic orientation to explicate and explore the notion of the grey zone of health and illness and seeks to develop the concept through an examination of the case of alcohol consumption. The grey zone is an interpretive area referring to the irremediable zone of ambiguity that haunts even the most apparently resolute discourse. This idea points to an ontological indeterminacy, in the face of which decisions have to be made with regard to the health of a person (e.g., an alcoholic), a system (e.g., the health system), or a society. The fundamental character of this notion will be developed in relation to the discourse on health and the limitations of different disciplinary practices. The case of alcohol consumption will be used to tease out the grey zone embedded in the different kinds of knowledge made available through the disciplinary traditions of medical science, with its emphasis on somatic well-being, and anthropology, with its focus on communal well-being. This tension or grey zone embedded in different knowledge outcomes will be shown to have a discursive parallel with the dialogue between the Athenian, the Spartan, and the Cretan in Plato's Laws. Making use of the dialogical approach as described by Gadamer, the Athenian's particular resolution of the tension will be explored as a case study to demonstrate the necessarily particular analysis involved in a grey zone resolution.

  14. The role of the poet in Plato's ideal cities of Callipolis and Magnesia

    Directory of Open Access Journals (Sweden)

    Gerard Naddaf

    2007-12-01

    Full Text Available Plato's attitude toward the poets and poetry has always been a flashpoint of debate, controversy and notoriety, but most scholars have failed to see their central role in the ideal cities of the Republic and the Laws, that is, Callipolis and Magnesia. In this paper, I argue that in neither dialogue does Plato "exile" the poets, but, instead, believes they must, like all citizens, exercise the expertise proper to their profession, allowing them the right to become full-fledged participants in the productive class. Moreover, attention to certain details reveals that Plato harnesses both positive and negative factors in poetry to bring his ideal cities closer to a practical realization. The status of the poet and his craft in this context has rarely to my knowledge been addressed.A atitude de Platão com relação aos poetas e à poesia tem sempre sido um ponto de debate, controvérsia e notoriedade, mas a maioria dos estudiosos não consegue ver seu papel central nas cidades ideais da República e das Leis, ou seja, Callipolis e Magnésia. Neste artigo, defendo que em nenhum dos dois diálogos Platão exila os poetas, mas, ao contrário, acredita que eles devem, como todos os cidadãos, exercitar a competência própria à sua profissão, permitindo-lhes o direito de se tornarem participantes com todos os direitos da classe produtora. Principalmente, se prestarmos a atenção devida em certos detalhes, veremos que Platão controla tanto os fatores positivos, como os negativos na poesia, para aproximar mais suas cidades ideais da realização prática. A meu ver, o estatuto do poeta e de sua habilidade, nesse contexto, foram raramente estudados.

  15. Kilowatt isotope power system, Phase II Plan. Volume IV. Teledyne FSCD vs GDS

    Energy Technology Data Exchange (ETDEWEB)

    1978-03-15

    This Volume contains Teledyne's input to the Kilowatt Isotope Power System Phase II Plan. Included is a description of the Flight System Heat Generation System, Flight System Radiator, Thermal Insulation Stability, GDS Heat Generation System and GDS Radiator.

  16. Dialectic of Eros and Myth of the Soul in Plato's Phaedrus

    DEFF Research Database (Denmark)

    Larsen, Jens Kristian

    2010-01-01

    In this paper, I question a widespread reading of a passage in the last part of the Phaedrus dealing with the science of dialectic. According to this reading, the passage announces a new method peculiar to the later Plato aiming at defining natural kinds. I show that the Phaedrus itself does not ...... not support such a reading. As an alternative reading, I suggest that the science of dialectic, as discussed in the passage, must be seen as dealing primarily with philosophical rhetoric and knowledge of human souls....

  17. Numbers Rule The Vexing Mathematics of Democracy, from Plato to the Present

    CERN Document Server

    Szpiro, George G

    2010-01-01

    Since the very birth of democracy in ancient Greece, the simple act of voting has given rise to mathematical paradoxes that have puzzled some of the greatest philosophers, statesmen, and mathematicians. Numbers Rule traces the epic quest by these thinkers to create a more perfect democracy and adapt to the ever-changing demands that each new generation places on our democratic institutions. In a sweeping narrative that combines history, biography, and mathematics, George Szpiro details the fascinating lives and big ideas of great minds such as Plato, Pliny the Younger, Ramon Llull, Pierre Simo

  18. [Plato's philosophy and the bioethical debate on the end of life: intersections in public health].

    Science.gov (United States)

    Siqueira-Batista, Rodrigo; Schramm, Fermin Roland

    2004-01-01

    This article discusses bioethical aspects of medical futility, focusing on some of its intersections in public health. Starting from a demarcation of finitude in the core of the philosophical and bioethical debate on the end of life, we confront the contemporary criticism regarding medical futility with the ideas of Plato (427-347 B.C.), a philosopher who proposed significant considerations on numerous features of the medicine of his time. We thus explore novel theoretic references to guide the disputes related to this essential problem, the implications of which are decisive to health and life.

  19. R and D programme on generation IV nuclear energy systems: the high temperatures gas-cooled reactors

    International Nuclear Information System (INIS)

    Carre, F.; Fiorini, G.L.; Billot, P.; Anzieu, P.; Brossard, P.

    2005-01-01

    The Generation IV Technology Roadmap selected, among others, a sequenced development of advanced high temperature gas cooled reactors as one of the main focus for R and D on future nuclear energy systems. The selection of this research objective originates both from the significance of high temperature and fast neutrons for nuclear energy to meet the needs for a sustainable development for the medium-long term (2020/2030 and beyond), and from the significant common R and D pathway that supports both medium term industrial projects and more advanced versions of gas cooled reactors. The first step of the 'Gas Technology Path' aims to support the development of a modular HTR to meet specific international market needs around 2020. The second step is a Very High Temperature Reactor - VHTR (>950 C) - to efficiently produce hydrogen through thermo-chemical or electro-chemical water splitting or to generate electricity with an efficiency above 50%, among other applications of high temperature nuclear heat. The third step of the Path is a Gas Fast Reactor - GFR - that features a fast-spectrum helium-cooled reactor and closed fuel cycle, with a direct or indirect thermodynamic cycle for electricity production and full recycle of actinides. Hydrogen production is also considered for the GFR. The paper succinctly presents the R and D program currently under definition and partially launched within the Generation IV International Forum on this consistent set of advanced gas cooled nuclear systems. (orig.)

  20. AUTOMOTIVE DIESEL MAINTENANCE 1. UNIT IV, MAINTAINING THE COOLING SYSTEM--DETROIT DIESEL ENGINES.

    Science.gov (United States)

    Human Engineering Inst., Cleveland, OH.

    THIS MODULE OF A 30-MODULE COURSE IS DESIGNED TO DEVELOP AN UNDERSTANDING OF THE OPERATION AND MAINTENANCE OF THE DIESEL ENGINE COOLING SYSTEM. TOPICS ARE PURPOSE OF THE COOLING SYSTEM, CARE MAINTENANCE OF THE COOLING SYSTEM, COOLING SYSTEM COMPONENTS, AND TROUBLESHOOTING TIPS. THE MODULE CONSISTS OF A SELF-INSTRUCTIONAL BRANCH PROGRAMED TRAINING…

  1. The Atalante facility at CEA/Marcoule: towards Gen IV systems fuel cycle

    Energy Technology Data Exchange (ETDEWEB)

    Bordier, Gilles; Warin, Dominique; Masson, Michel [CEA/Marcoule Direction, BP 17171 - 30207 - Bagnols-sur-Ceze Cedex (France)

    2008-07-01

    The Atalante facility is a complete set of 18 hot labs and 9 shielded cells devoted to the research and development on fuel cycle. The activities correspond to 4 major sectors of nuclear research: -) to support the operation of actual reprocessing plants with the aim of adapting the head of the process to the increase of the spend fuel burn-up and to different types of new burnt fuels to be reprocessed (including MOX, USi or UMo fuels); -) to develop the COEX{sup TM} process that jointly manages uranium and plutonium from the dissolution of spent fuel to the production of UPuO{sub 2} powder and the fabrication of MOX fuel pellets; -) to prepare the recycling of minor actinides (MA) by partitioning or by grouped actinide extraction, and by MA bearing fuel fabrication; -) to study the long term behavior of high level waste conditioning matrices and especially self irradiation and leaching of vitrified waste. The first hot lab of Atalante was operated in 1992, the process shielded cell (CBP) in 2003 and the last LN1 lab in 2005, while at the same time a large scale demonstration test on the DIAMEX-SANEX MA partitioning process was performed. Now some new challenges involve further necessary evolutions of the facility. Some are related to safety assessment and operating flexibility; the major evolutions will come from new scientific goals and research programs. Furthermore, minor actinides materials irradiation tests in fast reactors will be prepared in the framework of a large international cooperation (GACID program) and need the production of significant amounts of MA bearing mixed U-Pu oxide compounds in new hot labs and shielded cells equipment. The major new research tools are presented and we highlight how Atalante is a unique facility which brings a real opportunity to reinforce the European and international scientific cooperation in order to prepare the next Gen IV fuel cycle. (authors)

  2. The Atalante facility at CEA/Marcoule: towards Gen IV systems fuel cycle

    International Nuclear Information System (INIS)

    Bordier, Gilles; Warin, Dominique; Masson, Michel

    2008-01-01

    The Atalante facility is a complete set of 18 hot labs and 9 shielded cells devoted to the research and development on fuel cycle. The activities correspond to 4 major sectors of nuclear research: -) to support the operation of actual reprocessing plants with the aim of adapting the head of the process to the increase of the spend fuel burn-up and to different types of new burnt fuels to be reprocessed (including MOX, USi or UMo fuels); -) to develop the COEX TM process that jointly manages uranium and plutonium from the dissolution of spent fuel to the production of UPuO 2 powder and the fabrication of MOX fuel pellets; -) to prepare the recycling of minor actinides (MA) by partitioning or by grouped actinide extraction, and by MA bearing fuel fabrication; -) to study the long term behavior of high level waste conditioning matrices and especially self irradiation and leaching of vitrified waste. The first hot lab of Atalante was operated in 1992, the process shielded cell (CBP) in 2003 and the last LN1 lab in 2005, while at the same time a large scale demonstration test on the DIAMEX-SANEX MA partitioning process was performed. Now some new challenges involve further necessary evolutions of the facility. Some are related to safety assessment and operating flexibility; the major evolutions will come from new scientific goals and research programs. Furthermore, minor actinides materials irradiation tests in fast reactors will be prepared in the framework of a large international cooperation (GACID program) and need the production of significant amounts of MA bearing mixed U-Pu oxide compounds in new hot labs and shielded cells equipment. The major new research tools are presented and we highlight how Atalante is a unique facility which brings a real opportunity to reinforce the European and international scientific cooperation in order to prepare the next Gen IV fuel cycle. (authors)

  3. Sensor System for Long-term Recording of Photovoltaic (PV) IV-curves

    DEFF Research Database (Denmark)

    Paasch, Kasper; Nymand, Morten; Haase, Frerk

    The purpose of this paper is to present a recording system for long-term investigation of PV panel dynamics under partial shading conditions. The system is intended to be a low-cost system deployable for stand-alone field use and long-term data recording at PV-plants. Passing clouds will affect...

  4. Chemiluminescent determination of vanadium(IV) using a cinchomeronic hydrazide-H2O2 system and flow injection analysis

    International Nuclear Information System (INIS)

    Pradana Perez, J.A.; Alegria, J.S. Durand; Hernando, P. Fernandez; Sierra, A. Narros

    2005-01-01

    This paper proposes a new chemiluminescent flow injection analysis (FIA) method for the determination of vanadium(IV) ions in aqueous media. The method is based on the chemiluminescent reaction that occurs between cinchomeronic hydrazide (CH) and hydrogen peroxide in a strongly alkaline medium, in which vanadium(IV) acts as a catalyst. The chemical and physical variables involved in the flow injection system are optimised using a modified simplex method. Vanadium ions can be detected in the 0.08 and 1.00 μg mL -1 range; the detection limit for a signal-to-noise ratio of 3 is 0.08 μg mL -1 . Great variations in the quantum yield were observed when cobalt(II), chromium(III), copper(II) and/or nickel(II) were present in the reaction medium. The proposed method is selective and simple, and can be successfully used to analyse water samples without the need for separation or preconcentration processes

  5. Wien Automatic System Planning (WASP) Package. A computer code for power generating system expansion planning. Version WASP-IV. User's manual

    International Nuclear Information System (INIS)

    2001-01-01

    As a continuation of its efforts to provide methodologies and tools to Member States to carry out comparative assessment and analyse priority environmental issues related to the development of the electric power sector, the IAEA has completed a new version of the Wien Automatic System Planning (WASP) Package WASP-IV for carrying out power generation expansion planning taking into consideration fuel availability and environmental constraints. This manual constitutes a part of this work and aims to provide users with a guide to use effectively the new version of the model WASP-IV. WASP was originally developed in 1972 by the Tennessee Valley Authority and the Oak Ridge National Laboratory in the USA to meet the IAEA needs to analyse the economic competitiveness of nuclear power in comparison to other generation expansion alternatives for supplying the future electricity requirements of a country or region. Previous versions of the model were used by Member States in many national and regional studies to analyse the electric power system expansion planning and the role of nuclear energy in particular. Experience gained from its application allowed development of WASP into a very comprehensive planning tool for electric power system expansion analysis. New, improved versions were developed, which took into consideration the needs expressed by the users of the programme in order to address important emerging issues being faced by the electric system planners. In 1979, WASP-IV was released and soon after became an indispensable tool in many Member States for generation expansion planning. The WASP-IV version was continually upgraded and the development of version WASP-III Plus commenced in 1992. By 1995, WASP-III Plus was completed, which followed closely the methodology of the WASP-III but incorporated new features. In order to meet the needs of electricity planners and following the recommendations of the Helsinki symposium, development of a new version of WASP was

  6. A simple Cr(VI)–S(IV)–O{sub 2} system for rapid and simultaneous reduction of Cr(VI) and oxidative degradation of organic pollutants

    Energy Technology Data Exchange (ETDEWEB)

    Yuan, Yanan; Yang, Shaojie [Department of Environmental Science, Hubei Key Lab of Biomass Resource Chemistry and Environmental Biotechnology, School of Resources and Environmental Science, Wuhan University, 430079 (China); Zhou, Danna, E-mail: zdncug@163.com [Faculty of Material Science and Chemistry, China University of Geosciences, Wuhan 430074 (China); Wu, Feng [Department of Environmental Science, Hubei Key Lab of Biomass Resource Chemistry and Environmental Biotechnology, School of Resources and Environmental Science, Wuhan University, 430079 (China)

    2016-04-15

    Highlights: • Rapid and simultaneous reduction of Cr(VI) and degradation of organic pollutants occur. • Oxysulfur radicals generated in Cr(VI)–S(IV)–O{sub 2} system oxidize the organic pollutants. • Acidic pH facilitates the reactions from both directions of reduction and oxidation. • Degradation potential of aromatic amines depends on the substituted groups. • Cr(VI)–S(IV)–O{sub 2} system is promising for “waste control by waste”. - Abstract: Hexavalent chromium (Cr(VI)), a heavy-metal contaminant, can be easily reduced to less toxic trivalent chromium (Cr(III)) by sulfite ions (S(IV)). However, S(IV) has not drawn as much attention as the ferrous ion has. We report herein a novel Cr(VI)–S(IV)–O{sub 2} system containing sulfite ions that rapidly and simultaneously reduces Cr(VI) and oxidize organic pollutants in the presence of oxygen in aqueous solutions. This Cr(VI)–S(IV)-O{sub 2} system contains the initiator Cr(VI), the reductant S(IV), and the oxidant O{sub 2}, which produce oxysulfur radicals (mainly SO{sub 4}·{sup −} and SO{sub 5}·{sup −}) and hydroxyl radicals (OH·). The Cr(VI)/S(IV) molar ratio, pH, and oxygen content play important roles in the entire reaction system. Acidic conditions (pH 3.0) facilitated degradation of organic compounds and reduction of Cr(VI) as well. In addition, experiments of rapid degradation of several kinds of organic pollutants such as azo dye (acid orange 7, AO7), aniline, phenol, bisphenol A etc were also conducted. Preliminary results show that the removal rates of the analogs of phenols or aromatic amines in this Cr(VI)–S(IV)–O{sub 2} system have a relationship with the electronic parameters (Hammett constant, σ) of the substituted groups. Thus, the Cr(VI)–S(IV)–O{sub 2} system, provides an excellent strategy of “waste control by waste” for removing multiple industrial contaminants.

  7. Separation method for ions of elements of the III., IV., VI. and VIII. groups of periodical system

    International Nuclear Information System (INIS)

    Marhol, M.

    1973-01-01

    The method is presented of separating the ions of the elements of the periodic system groups III, IV, and VIII by ion exchangers. The ions are complex-bonded to a new type of ion exchanger consisting of the polycondensates of phenol with aldehydes or ketones and containing an atom of phosphorus, arsenic or antimony with an atom of sulphur or oxygen in a complex bond. The polymers of compounds containing a double bond, e.g., of butadiene, polyvinyl alcohol, polyethylene, polypropylene, and the compounds of styrene with fural may also be used for this purpose. The method is demonstrated on a case of uranium and heavy metal concentration and the separation thereof from waste waters. (L.K.)

  8. Analysis of 235U enrichment by chemical exchange in U(IV) - U(VI) system on anionite

    International Nuclear Information System (INIS)

    Raica, Paula; Axente, Damian

    2007-01-01

    Full text: A theoretical study about the 235 U enrichment by chemical exchange method in U(IV)-U(VI) system on anion-exchange resins is presented. The 235 U isotope concentration profiles along the band were numerically calculated using an accurate mathematical model and simulations were carried out for the situation of product and waste withdrawal and feed supply. By means of numerical simulation, an estimation of the migration time, necessary for a desired enrichment degree, was obtained. The required migration distance, the production of uranium 3 at.% 235 U per year and the plant configuration are calculated for different operating conditions. An analysis of the process scale for various experimental conditions is also presented. (authors)

  9. Conversion of actinide solutions for the production of MA bearing fuels for Gen IV fast reactor systems

    International Nuclear Information System (INIS)

    Fernandez, A.; McGinley, J.; Somers, J.

    2008-01-01

    The conversion of the solution to solid for fuels containing minor actinides for accelerator driven systems or Gen IV fast reactors cannot be made by conventional ammonia or oxalate precipitation as is the case in today's reprocessing plant. The small particle size and concomitant dust that is produced in subsequent processing steps will not permit use of these processes on industrial scale. Innovation is needed to avoid dust generating powders, and indeed to simplify the processes themselves. Two such processing routes have been developed at the JRC-ITU. The sol gel route has been used to produce fuel containing Am and Np for the SUPERFACT, TRABANT and other irradiation experiments. The infiltration process has also been established and fuels have been produced for the FUTURIX and HELIOS experiments. (authors)

  10. Conversion of actinide solutions for the production of MA bearing fuels for Gen IV fast reactor systems

    Energy Technology Data Exchange (ETDEWEB)

    Fernandez, A.; McGinley, J.; Somers, J. [European Commission, Joint Research Centre, Institute for Transuranium Elements P.O.Box 2340, Karlsruhe, D-76125 (Germany)

    2008-07-01

    The conversion of the solution to solid for fuels containing minor actinides for accelerator driven systems or Gen IV fast reactors cannot be made by conventional ammonia or oxalate precipitation as is the case in today's reprocessing plant. The small particle size and concomitant dust that is produced in subsequent processing steps will not permit use of these processes on industrial scale. Innovation is needed to avoid dust generating powders, and indeed to simplify the processes themselves. Two such processing routes have been developed at the JRC-ITU. The sol gel route has been used to produce fuel containing Am and Np for the SUPERFACT, TRABANT and other irradiation experiments. The infiltration process has also been established and fuels have been produced for the FUTURIX and HELIOS experiments. (authors)

  11. Functional performance of the helical coil steam generator, Consolidated Nuclear Steam Generator (CNSG) IV system. Executive summary report

    International Nuclear Information System (INIS)

    Watson, G.B.

    1975-10-01

    The objective of this project was to study the functional performance of the CNSG - IV helical steam generator to demonstrate that the generator meets steady-state and transient thermal-hydraulic performance specifications and that secondary flow instability will not be a problem. Economic success of the CNSG concepts depends to a great extent on minimizing the size of the steam generator and the reactor vessel for ship installation. Also, for marine application the system must meet stringent specifications for operating stability, transient response, and control. The full-size two-tube experimental unit differed from the CNSG only in the number of tubes and the mode of primary flow. In general, the functional performance test demonstrated that the helical steam generator concept will exceed the specified superheat of 35F at 100% load. The experimental measured superheat at comparable operating conditions was 95F. Testing also revealed that available computer codes accurately predict trends and overall performance characteristics

  12. Social developmnet of ecologically sensitive rural areas: Case studies of the Moravian Karst (Czech Republic) and the Devetashko Plato (Bulgaria)

    Czech Academy of Sciences Publication Activity Database

    Zapletalová, Jana; Stefanová, D.; Vaishar, Antonín; Stefanov, P.; Dvořák, Petr; Tcherkezova, E.

    3-4, 3-4 (2016), s. 65-84 ISSN 0204-7209 Institutional support: RVO:68145535 Keywords : social development * rural sensitive areas * Devetashko Plato * Bulgaria * Moravian karst - Czech Republic Subject RIV: DE - Earth Magnetism, Geodesy, Geography OBOR OECD: Cultural and economic geography http://geoproblems.eu/wp-content/uploads/2017/04/2016_34/4_zapletalova.pdf

  13. Transit Timing Observations from Kepler: IV. Confirmation of 4 Multiple Planet Systems by Simple Physical Models

    Energy Technology Data Exchange (ETDEWEB)

    Fabrycky, Daniel C.; /UC, Santa Cruz; Ford, Eric B.; /Florida U.; Steffen, Jason H.; /Fermilab; Rowe, Jason F.; /SETI Inst., Mtn. View /NASA, Ames; Carter, Joshua A.; /Harvard-Smithsonian Ctr. Astrophys.; Moorhead, Althea V.; /Florida U.; Batalha, Natalie M.; /San Jose State U.; Borucki, William J.; /NASA, Ames; Bryson, Steve; /NASA, Ames; Buchhave, Lars A.; /Bohr Inst. /Copenhagen U.; Christiansen, Jessie L.; /SETI Inst., Mtn. View /NASA, Ames /Caltech

    2012-01-01

    Eighty planetary systems of two or more planets are known to orbit stars other than the Sun. For most, the data can be sufficiently explained by non-interacting Keplerian orbits, so the dynamical interactions of these systems have not been observed. Here we present 4 sets of lightcurves from the Kepler spacecraft, which each show multiple planets transiting the same star. Departure of the timing of these transits from strict periodicity indicates the planets are perturbing each other: the observed timing variations match the forcing frequency of the other planet. This confirms that these objects are in the same system. Next we limit their masses to the planetary regime by requiring the system remain stable for astronomical timescales. Finally, we report dynamical fits to the transit times, yielding possible values for the planets masses and eccentricities. As the timespan of timing data increases, dynamical fits may allow detailed constraints on the systems architectures, even in cases for which high-precision Doppler follow-up is impractical.

  14. R and D study on on-line criticality surveillance system (IV)

    International Nuclear Information System (INIS)

    Yamada, Sumasu

    2000-02-01

    Developing an inexpensive on-line criticality surveillance system is required for ensuring the safety of nuclear fuel reprocessing plants. Based on the series of researches for five years, R and D study on On-line Criticality Surveillance system has been carried out since 1996. The concept of this Criticality Surveillance System is based on the Auto-Regressive Moving Average (ARMA) model identification algorithms to the time series of signal fluctuation of a neutron detector. We have proposed several new ideas of modification to the original design of the Criticality Surveillance System, and also reported some results of numerical analysis over the DCA experiments. In those days, DOS/V personal computers with Microsoft Windows have came into wide use instead of those based on the MS-DOS, which have been popular in Japan. NEC, a major maker of MS-DOS computers, stopped the production of MS-DOS computers and changed their management policy toward production of DOS/V personal computers. Our researches have been developed using MS-DOS computers. For the effective use of these important results, it became an urgent theme to transplant all programs developed on MS-DOS computers into computers with the OS, which is not easily affected by commercialism. Since the design concept should be based on high reliability, electromagnetic disturbance-free and high expandability, and also computers have achieved remarkably high performance as well as low price in these days, these computers should be used not only as a simple signal processing unit but also a totally integrated signal analyzing system along with conventional signal analyzing software in stead of IC chips with analyzing soft wares. This configuration enables us to easily introduce newly developed techniques and to provide supplement information. Then, this approach can enhance the reliability of the Criticality Surveillance System without addition of any special devices, and also provide the flexibility of the system

  15. Tank Waste Remediation System, Hanford Site, Richland, Washington. Final Environmental Impact Statement. Volume IV

    International Nuclear Information System (INIS)

    1996-08-01

    This document, Volume 4, describes the current safety concerns associated with the tank waste and analyzes the potential accidents and associated potential health effects that could occur under the alternatives included in this Tank Waste Remediation System (TWRS) Final Environmental Impact Statement (EIS) for the Hanford Site, Richland, Washington

  16. Session IV. Problem Solving. Vehicle lighting system. Four steps in glare reduction.

    NARCIS (Netherlands)

    Schreuder, D.A.

    1972-01-01

    A number of proposals are described that may help to reduce glare. The systems are either only a partial improvement, or they are expensive, or their introduction raises severe problems. One solution, already widely in use, is applica- tion of overhead lighting. In order to really improve the

  17. Instructional Coding System for Mathematics Program of Studies. MET, A Title IV-C Project.

    Science.gov (United States)

    Fairfax County Public Schools, VA. Dept. of Instructional Services.

    This document is part of the Management for Effective Teaching (MET) support kit, a pilot project designed by the Fairfax County (Virginia) Public Schools to assist elementary school teachers in planning, managing, and implementing the county's Program of Studies (POS). This document provides an alpha-numeric coding system to be used in…

  18. Electrical Procedures and Environmental Control Systems. Building Maintenance. Module IV. Instructor's Guide.

    Science.gov (United States)

    Sloan, Garry

    This curriculum guide, one of six modules keyed to the building maintenance competency profile developed by industry and education professionals, provides materials for two units on electrical procedures and environmental control systems. Unit 1, on electrical procedures, includes the following lessons: electrical safety; troubleshooting and…

  19. NJOY nuclear data processing system. Volume IV. The ERRORR and COVR modules

    International Nuclear Information System (INIS)

    Muir, D.W.; MacFarlane, R.E.

    1985-12-01

    The NJOY nuclear data processing system is a comprehensive computer code package for producing cross sections and related nuclear parameters from ENDF/B evaluated nuclear data. This volume provides detailed descriptions of the NJOY modules ERRORR and COVR, which are concerned with the covariances (uncertainties and correlations) of multigroup cross sections and fission neutron yield (anti nu) values. 17 refs

  20. System Engineering on the Use for Ares I,V - the Simpler, the Better

    Science.gov (United States)

    Kelly, William; Greene, William D.; Greasley, Paul; Ackerman, Peter C.

    2008-01-01

    The Ares I and Ares V Vehicles will utilize the J-2X rocket engine developed for NASA by the Pratt & Whitney Rocketdyne Company. The J-2X is an improved higher power version of the original J-2 engine used during the Apollo program. With higher power and updated requirements for safety and performance, the J-2X becomes a new engine using state-of-the-art design methodology, materials and manufacturing processes. The implementation of Systems Engineering (SE) principles enables the rapid J-2X development program to remain aligned with the ARES I and V vehicle programs, Meeting the aggressive development schedule is a challenge. Coordinating the best expertise thai NASA and PWR have to offer requires effectively utilizing resources at multiple sites. This presents formidable communication challenges. SE allows honest and open discussions of issues and problems. This simple idea is often overlooked in large and complex SE programs. Regular and effective meetings linking SE objectives to component designs are used to voice differences of opinions with customer and contractor in attendance so that the best mutual decisions can be made on the shortest possible schedule. Regular technical interchange meetings on secure program wide computer networks and CM processes are effective,in the "Controlled Change" process that exemplifies good SE. Good communication is a key effective SE implementation. The System of Systems approach is the vision of the Orion program which facilitates the establishment of dynamic SE processes at all levels including the engine. SE enables requirements evolution by facilitating organizational and process agility. Flow down and distribution of requirements is controlled by Allocation Reports which breakdown numerical design objectives (weight, reliability, etc.) into quanta goals for each component area. Linked databases of design and verification requirements helps eliminate redundancy and potential mistakes inherent m separated systems. Another

  1. Synergies Between the Kepler, K2 and TESS Missions with the PLATO Mission (Revised)

    Science.gov (United States)

    Jenkins, Jon M.

    2017-01-01

    Two transit survey missions will have been flown by NASA prior to the launch of ESA's PLATO Mission in 2026, laying the groundwork for exoplanet discovery via the transit method. The Kepler Mission, which launched in 2009, collected data on its 100+ square degree field of view for four years before failure of a reaction wheel ended its primary mission. The results from Kepler include 2300+ confirmed or validated exoplanets, 2200+ planetary candidates, 2100+ eclipsing binaries. Kepler also revolutionized the field of asteroseismology by measuring the pressure mode oscillations of over 15000 solar-like stars spanning the lifecycle of such stars from hydrogen-burning dwarfs to helium-burning red giants. The re-purposed Kepler Mission, dubbed K2, continues to observe fields of view in and near the ecliptic plane for 80 days each, significantly broadening the scope of the astrophysical investigations as well as discovering an additional 156 exoplanets to date. The TESS mission will launch in 2017 to conduct an all-sky survey for small exoplanets orbiting stars 10X closer and 100X brighter than Kepler exoplanet host stars, allowing for far greater follow-up and characterization of their masses as well as their sizes for at least 50 small planets. Future assets such as James Webb Space Telescope, and ground-based assets such as ESOs Very Large Telescope (VLT) array, the Exremely Large Telescope (ELT), and the Thirty Meter Telescope (TMT) will be able to characterize the atmospheric composition and properties of these small planets. TESS will observe each 24 X 96 field of view for 30 days and thereby cover first the southern and then the northern hemisphere over 13 pointings during each year of the primary mission. The pole-most camera will observe the James Webb continuous viewing zone for one year in each hemisphere, permitting much longer period planets to be detected in this region. The PLATO mission will seek to detect habitable Earth-like planets with an instrument

  2. Robo-AO Kepler Survey. IV. The Effect of Nearby Stars on 3857 Planetary Candidate Systems

    Science.gov (United States)

    Ziegler, Carl; Law, Nicholas M.; Baranec, Christoph; Riddle, Reed; Duev, Dmitry A.; Howard, Ward; Jensen-Clem, Rebecca; Kulkarni, S. R.; Morton, Tim; Salama, Maïssa

    2018-04-01

    We present the overall statistical results from the Robo-AO Kepler planetary candidate survey, comprising of 3857 high-angular resolution observations of planetary candidate systems with Robo-AO, an automated laser adaptive optics system. These observations reveal previously unknown nearby stars blended with the planetary candidate host stars that alter the derived planetary radii or may be the source of an astrophysical false positive transit signal. In the first three papers in the survey, we detected 440 nearby stars around 3313 planetary candidate host stars. In this paper, we present observations of 532 planetary candidate host stars, detecting 94 companions around 88 stars; 84 of these companions have not previously been observed in high resolution. We also report 50 more-widely separated companions near 715 targets previously observed by Robo-AO. We derive corrected planetary radius estimates for the 814 planetary candidates in systems with a detected nearby star. If planetary candidates are equally likely to orbit the primary or secondary star, the radius estimates for planetary candidates in systems with likely bound nearby stars increase by a factor of 1.54, on average. We find that 35 previously believed rocky planet candidates are likely not rocky due to the presence of nearby stars. From the combined data sets from the complete Robo-AO KOI survey, we find that 14.5 ± 0.5% of planetary candidate hosts have a nearby star with 4″, while 1.2% have two nearby stars, and 0.08% have three. We find that 16% of Earth-sized, 13% of Neptune-sized, 14% of Saturn-sized, and 19% of Jupiter-sized planet candidates have detected nearby stars.

  3. Accuracy evaluation of fusion of CT, MR, and SPECT images using commercially available software packages (SRS PLATO and IFS)

    International Nuclear Information System (INIS)

    Mongioj, Valeria; Brusa, Anna; Loi, Gianfranco; Pignoli, Emanuele; Gramaglia, Alberto; Scorsetti, Marta; Bombardieri, Emilio; Marchesini, Renato

    1999-01-01

    Purpose: A problem for clinicians is to mentally integrate information from multiple diagnostic sources, such as computed tomography (CT), magnetic resonance (MR), and single photon emission computed tomography (SPECT), whose images give anatomic and metabolic information. Methods and Materials: To combine this different imaging procedure information, and to overlay correspondent slices, we used commercially available software packages (SRS PLATO and IFS). The algorithms utilize a fiducial-based coordinate system (or frame) with 3 N-shaped markers, which allows coordinate transformation of a clinical examination data set (9 spots for each transaxial section) to a stereotactic coordinate system. The N-shaped markers were filled with fluids visible in each modality (gadolinium for MR, calcium chloride for CT, and 99m Tc for SPECT). The frame is relocatable, in the different acquisition modalities, by means of a head holder to which a face mask is fixed so as to immobilize the patient. Position errors due to the algorithms were obtained by evaluating the stereotactic coordinates of five sources detectable in each modality. Results: SPECT and MR position errors due to the algorithms were evaluated with respect to CT: Δx was ≤ 0.9 mm for MR and ≤ 1.4 mm for SPECT, Δy was ≤ 1 mm and ≤ 3 mm for MR and SPECT, respectively. Maximal differences in distance between estimated and actual fiducial centers (geometric mismatch) were in the order of the pixel size (0.8 mm for CT, 1.4 mm for MR, and 1.8 mm for SPECT). In an attempt to distinguish necrosis from residual disease, the image fusion protocol was studied in 35 primary or metastatic brain tumor patients. Conclusions: The image fusion technique has a good degree of accuracy as well as the potential to improve the specificity of tissue identification and the precision of the subsequent treatment planning

  4. Internet Economics IV

    Science.gov (United States)

    2004-08-01

    edts.): Internet Economics IV Technical Report No. 2004-04, August 2004 Information Systems Laboratory IIS, Departement of Computer Science University of...level agreements (SLA), Information technology (IT), Internet address, Internet service provider 16. PRICE CODE 17. SECURITY CLASSIFICATION 18... technology and its economic impacts in the Internet world today. The second talk addresses the area of AAA protocol, summarizing authentication

  5. A Review of Alloy 800H for Applications in the Gen IV Nuclear Energy Systems

    International Nuclear Information System (INIS)

    Ren, Weiju; Swindeman, Robert W.

    2010-01-01

    Alloy 800H is currently under consideration for applications in the Next Generation Nuclear Plant at operational temperatures above 750 C. To provide supporting information in this paper at the attempt to facilitate the consideration, service requirements of the nuclear system for structural materials is first described; and then an extensive review of Alloy 800H is given on its codification with respect to development and research history, mechanical behavior and design allowables, metallurgical aging resistance, environmental effect considerations, data requirements and availability, weldments, as well as many other aspects relevant to the intended nuclear application; an finally further research and development activities to support the materials qualification are suggested.

  6. Diagnostic method for photovoltaic systems based on light I-V measurements

    DEFF Research Database (Denmark)

    Spataru, Sergiu; Sera, Dezso; Kerekes, Tamas

    2015-01-01

    , be it external, such as shading or soiling, or degradation or failure of the PV modules and balance-of-system components. This allows for performing preventive and/or reparative maintenance, thus minimizing further losses and costs. This article proposes a complete diagnostic method for detecting shading...... and analysis of the diagnostic parameters and logic was performed based on module level tests on standard crystalline silicon PV modules, and were optimized to detect even small partial shading and increase series-resistance losses. To demonstrate the practical application and operation of this method...

  7. Structural Analysis via Generalized Interactive Graphics - STAGING. Volume IV. Appendices to System Manual.

    Science.gov (United States)

    1979-09-01

    INCLUDE READR DBO INCLUDE PWRITE DEC INCLUDE RWRITER DBO INCLUDE FCHPHAM DEC INCLUDE SETPHAM DEC INCLUDE FETSTAT DEC INCLUDE WRITE Figure B-6. System and...SY’STEM 1/3) OUTINE LENGTHS 21r L -N .-AAGE COMPASS A SN S F,3 )E JN 0A, Y N~TRk POINTS CAN 3f. ALLID df: RFAOR RWRjTE ;RWRrTER WRITE CLOSE THIS PvC)G’ A... IELT -----O ’) 8 . OL.F. . .DBDRT. IDaDAD IDBJLF ICKAGT DELPIC ENTRY CLASS: MAIN SEGMENT: (DE0) DESCI DELETE ANO DEACTIVATE ALL PICKED 2EAOS ON A LEVEL

  8. Classification review of dental adhesive systems: from the IV generation to the universal type

    OpenAIRE

    Sofan, Eshrak; Sofan, Afrah; Palaia, Gaspare; Tenore, Gianluca; Romeo, Umberto; Migliau, Guido

    2017-01-01

    Adhesive dentistry has undergone great progress in the last decades. In light of minimal-invasive dentistry, this new approach promotes a more conservative cavity design, which relies on the effectiveness of current enamel-dentine adhesives. Adhesive dentistry began in 1955 by Buonocore on the benefits of acid etching. With changing technologies, dental adhesives have evolved from no-etch to total-etch (4th and 5th generation) to self-etch (6th, 7th and 8th generation) systems. Currently, bon...

  9. A Study of Future Communications Concepts and Technologies for the National Airspace System - Part IV

    Science.gov (United States)

    Ponchak, Denise S.; Apaza, Rafael D.; Wichgers, Joel M.; Haynes, Brian; Roy, Aloke

    2015-01-01

    The National Aeronautics and Space Administration (NASA) Glenn Research Center (GRC) is investigating current and anticipated wireless communications concepts and technologies that the National Airspace System (NAS) may need in the next 50 years. NASA has awarded three NASA Research Announcements (NAR) studies with the objective to determine the most promising candidate technologies for air-to-air and air-to-ground data exchange and analyze their suitability in a post-NextGen NAS environment. This paper will present the final results describing the communications challenges and opportunities that have been identified as part of the study.

  10. Progress in the development of the neutron flux monitoring system of the French GEN-IV SFR: simulations and experimental validations [ANIMMA--2015-IO-98

    Energy Technology Data Exchange (ETDEWEB)

    Jammes, C.; Filliatre, P.; De Izarra, G. [CEA, DEN, DER, Instrumentation, Sensors and Dosimetry Laboratory, Cadarache, F-13108 Saint-Paul-lez-Durance, (France); Elter, Zs.; Pazsit, I. [Chalmers University of Technology, Department of Applied Physics, Division of Nuclear Engineering, SE-412 96 Goteborg, (Sweden); Verma, V.; Hellesen, C.; Jacobsson, S. [Division of Applied Nuclear Physics, Uppsala University, Box 516, SE-75120 Uppsala, (Sweden); Hamrita, H.; Bakkali, M. [CEA, DRT, LIST, Sensors and Electronic Architecture Laboratory, Saclay, F-91191 Gif Sur Yvette, (France); Chapoutier, N.; Scholer, A-C.; Verrier, D. [AREVA NP, 10 rue Juliette Recamier F-69456 Lyon, (France); Cantonnet, B.; Nappe, J-C. [PHONIS France S.A.S, Nuclear Instrumentation, Avenue Roger Roncier, B.P. 520, F-19106 Brive Cedex, (France); Molinie, P.; Dessante, P.; Hanna, R.; Kirkpatrick, M.; Odic, E. [Supelec, Department of Power and Energy System, F-91192 Gif Sur Yvette, (France); Jadot, F. [CEA, DEN, DER, ASTRID Project Group, Cadarache, F-13108 Saint-Paul-lez-Durance, (France)

    2015-07-01

    The neutron flux monitoring system of the French GEN-IV sodium-cooled fast reactor will rely on high temperature fission chambers installed in the reactor vessel and capable of operating over a wide-range neutron flux. The definition of such a system is presented and the technological solutions are justified with the use of simulation and experimental results. (authors)

  11. Classification review of dental adhesive systems: from the IV generation to the universal type

    Science.gov (United States)

    Sofan, Eshrak; Sofan, Afrah; Palaia, Gaspare; Tenore, Gianluca; Romeo, Umberto; Migliau, Guido

    2017-01-01

    Summary Adhesive dentistry has undergone great progress in the last decades. In light of minimal-invasive dentistry, this new approach promotes a more conservative cavity design, which relies on the effectiveness of current enamel-dentine adhesives. Adhesive dentistry began in 1955 by Buonocore on the benefits of acid etching. With changing technologies, dental adhesives have evolved from no-etch to total-etch (4th and 5th generation) to self-etch (6th, 7th and 8th generation) systems. Currently, bonding to dental substrates is based on three different strategies: 1) etch-and-rinse, 2) self-etch and 3) resin-modified glass-ionomer approach as possessing the unique properties of self-adherence to the tooth tissue. More recently, a new family of dentin adhesives has been introduced (universal or multi-mode adhesives), which may be used either as etch-and-rinse or as self-etch adhesives. The purpose of this article is to review the literature on the current knowledge for each adhesive system according to their classification that have been advocated by many authorities in most operative/restorative procedures. As noted by several valuable studies that have contributed to understanding of bonding to various substrates helps clinicians to choose the appropriate dentin bonding agents for optimal clinical outcomes. PMID:28736601

  12. IEA Implementing Agreement on Electricity Networks Analysis, Research and Development (ENARD) Annex IV: - Transmission Systems Final report

    Energy Technology Data Exchange (ETDEWEB)

    Uhlen, Kjetil; Cirio, Diego

    2012-11-01

    This is the final report from Annex IV under the IEA Implementing Agreement on Electricity Networks Analysis, Research and Development (ENARD). The Annex has worked out a long-term perspective in the evolution of transmission system planning and operation. This is motivated by the established targets for energy system developments, which in turn are affected by economic paradigms, environmental concerns, and security of supply requirements for the well-being of citizens. The Annex work concludes that urgent action is needed to make the power system able to accommodate in a safe and economic way the dramatic changes it is required to undergo. A main message is that the 'right' investment in transmission capacity, which must be stimulated, may be regarded as 'overinvestment'. Transmission lines may be 'necessary' even though there is a chance that they may be underutilised in parts of their lifetime. In reality, underinvestment could be more costly than overinvestment (contradictory to the motivation for deregulation; to improve efficiency and avoid overinvestment). This is necessary, taking into account the very long planning and consenting processes and accounting for the technical aspects in the regulatory and market framework.(auth)

  13. Efficient methods for solving discrete topology design problems in the PLATO-N project

    DEFF Research Database (Denmark)

    Canh, Nam Nguyen; Stolpe, Mathias

    This paper considers the general multiple load structural topology design problems in the framework of the PLATO-N project. The problems involve a large number of discrete design variables and were modeled as a non-convex mixed 0–1 program. For the class of problems considered, a global...... optimization method based on the branch-and-cut concept was developed and implemented. In the method a large number of continuous relaxations were solved. We also present an algorithm for generating cuts to strengthen the quality of the relaxations. Several heuristics were also investigated to obtain efficient...... algorithms. The branch and cut method is used to solve benchmark examples which can be used to validate other methods and heuristics....

  14. Simulation of n-qubit quantum systems. IV. Parametrizations of quantum states, matrices and probability distributions

    Science.gov (United States)

    Radtke, T.; Fritzsche, S.

    2008-11-01

    Entanglement is known today as a key resource in many protocols from quantum computation and quantum information theory. However, despite the successful demonstration of several protocols, such as teleportation or quantum key distribution, there are still many open questions of how entanglement affects the efficiency of quantum algorithms or how it can be protected against noisy environments. The investigation of these and related questions often requires a search or optimization over the set of quantum states and, hence, a parametrization of them and various other objects. To facilitate this kind of studies in quantum information theory, here we present an extension of the FEYNMAN program that was developed during recent years as a toolbox for the simulation and analysis of quantum registers. In particular, we implement parameterizations of hermitian and unitary matrices (of arbitrary order), pure and mixed quantum states as well as separable states. In addition to being a prerequisite for the study of many optimization problems, these parameterizations also provide the necessary basis for heuristic studies which make use of random states, unitary matrices and other objects. Program summaryProgram title: FEYNMAN Catalogue identifier: ADWE_v4_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/ADWE_v4_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 24 231 No. of bytes in distributed program, including test data, etc.: 1 416 085 Distribution format: tar.gz Programming language: Maple 11 Computer: Any computer with Maple software installed Operating system: Any system that supports Maple; program has been tested under Microsoft Windows XP, Linux Classification: 4.15 Does the new version supersede the previous version?: Yes Nature of problem: During the last decades

  15. Refractory Abundances of Terrestrial Planets and Their Stars: Testing [Si/Fe] Correlations with TESS and PLATO

    Science.gov (United States)

    Wolfgang, Angie; Fortney, Jonathan

    2018-01-01

    In standard models for planet formation, solid material in protoplanetary disks coagulate and collide to form rocky bodies. It therefore seems reasonable to assume that their chemical composition will follow the abundances of refractory elements, such as Si and Fe, in the host star, which has also accreted material from the disk. Backed by planet formation simulations which validate this assumption, planetary internal structure models have begun to use stellar abundances to break degeneracies in low-mass planet compositions inferred only from mass and radius. Inconveniently, our own Solar System contradicts this approach, as its terrestrial bodies exhibit a range of rock/iron ratios and the Sun's [Si/Fe] ratio is offset from the mean planetary [Si/Fe]. In this work, we explore what number and quality of observations we need to empirically measure the exoplanet-star [Si/Fe] correlation, given future transit missions, RV follow-up, and stellar characterization. Specifically, we generate synthetic datasets of terrestrial planet masses and radii and host star abundances assuming that the planets’ bulk [Si/Fe] ratio exactly tracks that of their host stars. We assign measurement uncertainties corresponding to expected precisions for TESS, PLATO, Gaia, and future RV instrumentation, and then invert the problem to infer the planet-star [Si/Fe] correlation given these observational constraints. Comparing the result to the generated truth, we find that 1% precision on the planet radii is needed to test whether [Si/Fe] ratios are correlated between exoplanet and host star. On the other hand, lower precisions can test for systematic offsets between planet and star [Si/Fe], which can constrain the importance of giant impacts for extrasolar terrestrial planet formation.

  16. Thermoelectric efficiency of IV-VI multiple quantumwell and superlattice systems

    International Nuclear Information System (INIS)

    Beyer, H.

    2001-09-01

    In this thesis the thermoelectric properties of PbTe-based multiple quantum well (MQW) and superlattice (SL) structures grown by molecular beam epitaxy (MBE) are investigated. The two approaches for an enhancement of the dimensionless thermoelectric figure of merit ZT = σS 2 T/λ (σ: electric conductivity, S: Seebeck coefficient, λ: thermal conductivity, T: temperature) in low dimensional structures are discussed: an enhancement of the two dimensional (2D) power factor σS 2 2D due to carrier confinement or a reduction of the thermal conductivity due to a modified phonon dispersion and stronger phonon scattering in layered structures. The novel PbTe/Pb 1-x Sr x Te-MQW system is investigated for a rise of the 2D power factor σS 2 2D . A detailed analysis of optical and electronic parameters based on infrared transmission spectra is performed. Only a small rise of the 2D power factor σS 2 2D for the MQW's compared to homogeneous epitaxial PbTe-layers is found. This smaller σS 2 2D -rise compared to first predictions for ideal MQW's is related to the finite barrier height and effects like lifting of the valley degeneracy or enhanced carrier scattering. However, a strong reduction of the thermal conductivity is found in MQW structures resulting in 2D ZT values between 0.5 and 1.0 at T = 300 K and up to 1.6 at T = 550 K. For the use in technical applications the three dimensional (3D) figure of merit of the whole structure ZT 3D must be raised. Different novel PbTe-based superlattice structures are investigated with respect to a 3D ZT-increase due to thermal conductivity reduction. ZT 3D -values of 0.33 for p-type PbTe-doping superlattices and of 0.45 at T = 300 K for PbTe/PbSe 20 Te 80 -SL's are determined (T = 300 K; n-PbTe: ZT max = 0.36, p-PbTe: ZT max = 0.30). Maximum ZT-values up to 1.25 for PbTe/PbSe 20 Te 80 -SL's and 1.20 for PbTe-doping SL's are estimated for temperatures between 450 K and 550 K. These values show the potential of these structures for

  17. PLANETS AROUND LOW-MASS STARS (PALMS). IV. THE OUTER ARCHITECTURE OF M DWARF PLANETARY SYSTEMS

    Energy Technology Data Exchange (ETDEWEB)

    Bowler, Brendan P. [California Institute of Technology, Division of Geological and Planetary Sciences, 1200 East California Boulevard, Pasadena, CA 91101 (United States); Liu, Michael C. [Institute for Astronomy, University of Hawai' i, 2680 Woodlawn Drive, Honolulu, HI 96822 (United States); Shkolnik, Evgenya L. [Lowell Observatory, 1400 West Mars Hill Road, Flagstaff, AZ 86001 (United States); Tamura, Motohide, E-mail: bpbowler@caltech.edu [National Astronomical Observatory of Japan, 2-21-1 Osawa, Mitaka, Tokyo 181-8588 (Japan)

    2015-01-01

    to single M dwarfs between 10-100 AU is 2.8{sub −1.5}{sup +2.4}%. Altogether we find that giant planets, especially massive ones, are rare in the outskirts of M dwarf planetary systems. Although the first directly imaged planets were found around massive stars, there is currently no statistical evidence for a trend of giant planet frequency with stellar host mass at large separations as predicted by the disk instability model of giant planet formation.

  18. Simulation results for PLATO: a prototype hybrid X-ray photon counting detector with a low energy threshold for fusion plasma diagnostics

    International Nuclear Information System (INIS)

    Habib, A.; Menouni, M.; Pangaud, P.; Morel, C.; Fenzi, C.; Colledani, G.; Moureau, G.; Escarguel, A.

    2017-01-01

    PLATO is a prototype hybrid X-ray photon counting detector that has been designed to meet the specifications for plasma diagnostics for the WEST tokamak platform (Tungsten (W) Environment in Steady-state Tokamak) in southern France, with potential perspectives for ITER. PLATO represents a customized solution that fulfills high sensitivity, low dispersion and high photon counting rate. The PLATO prototype matrix is composed of 16 × 18 pixels with a 70 μm pixel pitch. New techniques have been used in analog sensitive blocks to minimize noise coupling through supply rails and substrate, and to suppress threshold dispersion across the matrix. The PLATO ASIC is designed in CMOS 0.13 μm technology and was submitted for a fabrication run in June 2016. The chip is designed to be bump-bonded to a silicon sensor. This paper presents pixel architecture as well as simulation results while highlighting novel solutions.

  19. Functional mapping of PilF and PilQ in the Pseudomonas aeruginosa type IV pilus system.

    Science.gov (United States)

    Koo, Jason; Tang, Tim; Harvey, Hanjeong; Tammam, Stephanie; Sampaleanu, Liliana; Burrows, Lori L; Howell, P Lynne

    2013-04-30

    Pseudomonas aeruginosa uses type IV pili (T4P) to interact with the environment and as key virulence factors when acting as an opportunistic pathogen. Assembly of the outer membrane PilQ secretin channel through which the pili are extruded is essential for pilus biogenesis. The P. aeruginosa T4P pilotin, PilF, is required for PilQ outer membrane localization and assembly into secretins and contains six tetratricopeptide (TPR) protein-protein interaction motifs, suggesting that the two proteins interact. In this study, we found that the first four TPR motifs of PilF are sufficient for PilQ outer membrane targeting, oligomerization, and function. Guided by our structure of PilF, site-directed mutagenesis of the protein surface revealed that a hydrophobic groove on the first TPR is required for PilF-mediated PilQ assembly. Deletion of individual domains within PilQ suggests that the N0, KH-like, or secretin domain, but not the C-terminus, interacts with PilF. Purified PilQ was found to pull down PilF from Pseudomonas cell lysates. Together, these data allow us to propose a model for PilF function in the T4P system. PilF interacts directly or indirectly with the PilQ monomer after translocation of both proteins through the inner membrane and acts as a co-chaperone with the Lol system to facilitate transit across the periplasm to the outer membrane. The mechanism of PilQ insertion and assembly, which appears to be independent of the Bam system, remains to be determined.

  20. Parallel Evolution of a Type IV Secretion System in Radiating Lineages of the Host-Restricted Bacterial Pathogen Bartonella

    Science.gov (United States)

    Engel, Philipp; Salzburger, Walter; Liesch, Marius; Chang, Chao-Chin; Maruyama, Soichi; Lanz, Christa; Calteau, Alexandra; Lajus, Aurélie; Médigue, Claudine; Schuster, Stephan C.; Dehio, Christoph

    2011-01-01

    Adaptive radiation is the rapid origination of multiple species from a single ancestor as the result of concurrent adaptation to disparate environments. This fundamental evolutionary process is considered to be responsible for the genesis of a great portion of the diversity of life. Bacteria have evolved enormous biological diversity by exploiting an exceptional range of environments, yet diversification of bacteria via adaptive radiation has been documented in a few cases only and the underlying molecular mechanisms are largely unknown. Here we show a compelling example of adaptive radiation in pathogenic bacteria and reveal their genetic basis. Our evolutionary genomic analyses of the α-proteobacterial genus Bartonella uncover two parallel adaptive radiations within these host-restricted mammalian pathogens. We identify a horizontally-acquired protein secretion system, which has evolved to target specific bacterial effector proteins into host cells as the evolutionary key innovation triggering these parallel adaptive radiations. We show that the functional versatility and adaptive potential of the VirB type IV secretion system (T4SS), and thereby translocated Bartonella effector proteins (Beps), evolved in parallel in the two lineages prior to their radiations. Independent chromosomal fixation of the virB operon and consecutive rounds of lineage-specific bep gene duplications followed by their functional diversification characterize these parallel evolutionary trajectories. Whereas most Beps maintained their ancestral domain constitution, strikingly, a novel type of effector protein emerged convergently in both lineages. This resulted in similar arrays of host cell-targeted effector proteins in the two lineages of Bartonella as the basis of their independent radiation. The parallel molecular evolution of the VirB/Bep system displays a striking example of a key innovation involved in independent adaptive processes and the emergence of bacterial pathogens

  1. Parallel evolution of a type IV secretion system in radiating lineages of the host-restricted bacterial pathogen Bartonella.

    Directory of Open Access Journals (Sweden)

    Philipp Engel

    2011-02-01

    Full Text Available Adaptive radiation is the rapid origination of multiple species from a single ancestor as the result of concurrent adaptation to disparate environments. This fundamental evolutionary process is considered to be responsible for the genesis of a great portion of the diversity of life. Bacteria have evolved enormous biological diversity by exploiting an exceptional range of environments, yet diversification of bacteria via adaptive radiation has been documented in a few cases only and the underlying molecular mechanisms are largely unknown. Here we show a compelling example of adaptive radiation in pathogenic bacteria and reveal their genetic basis. Our evolutionary genomic analyses of the α-proteobacterial genus Bartonella uncover two parallel adaptive radiations within these host-restricted mammalian pathogens. We identify a horizontally-acquired protein secretion system, which has evolved to target specific bacterial effector proteins into host cells as the evolutionary key innovation triggering these parallel adaptive radiations. We show that the functional versatility and adaptive potential of the VirB type IV secretion system (T4SS, and thereby translocated Bartonella effector proteins (Beps, evolved in parallel in the two lineages prior to their radiations. Independent chromosomal fixation of the virB operon and consecutive rounds of lineage-specific bep gene duplications followed by their functional diversification characterize these parallel evolutionary trajectories. Whereas most Beps maintained their ancestral domain constitution, strikingly, a novel type of effector protein emerged convergently in both lineages. This resulted in similar arrays of host cell-targeted effector proteins in the two lineages of Bartonella as the basis of their independent radiation. The parallel molecular evolution of the VirB/Bep system displays a striking example of a key innovation involved in independent adaptive processes and the emergence of bacterial

  2. Parallel evolution of a type IV secretion system in radiating lineages of the host-restricted bacterial pathogen Bartonella.

    Science.gov (United States)

    Engel, Philipp; Salzburger, Walter; Liesch, Marius; Chang, Chao-Chin; Maruyama, Soichi; Lanz, Christa; Calteau, Alexandra; Lajus, Aurélie; Médigue, Claudine; Schuster, Stephan C; Dehio, Christoph

    2011-02-10

    Adaptive radiation is the rapid origination of multiple species from a single ancestor as the result of concurrent adaptation to disparate environments. This fundamental evolutionary process is considered to be responsible for the genesis of a great portion of the diversity of life. Bacteria have evolved enormous biological diversity by exploiting an exceptional range of environments, yet diversification of bacteria via adaptive radiation has been documented in a few cases only and the underlying molecular mechanisms are largely unknown. Here we show a compelling example of adaptive radiation in pathogenic bacteria and reveal their genetic basis. Our evolutionary genomic analyses of the α-proteobacterial genus Bartonella uncover two parallel adaptive radiations within these host-restricted mammalian pathogens. We identify a horizontally-acquired protein secretion system, which has evolved to target specific bacterial effector proteins into host cells as the evolutionary key innovation triggering these parallel adaptive radiations. We show that the functional versatility and adaptive potential of the VirB type IV secretion system (T4SS), and thereby translocated Bartonella effector proteins (Beps), evolved in parallel in the two lineages prior to their radiations. Independent chromosomal fixation of the virB operon and consecutive rounds of lineage-specific bep gene duplications followed by their functional diversification characterize these parallel evolutionary trajectories. Whereas most Beps maintained their ancestral domain constitution, strikingly, a novel type of effector protein emerged convergently in both lineages. This resulted in similar arrays of host cell-targeted effector proteins in the two lineages of Bartonella as the basis of their independent radiation. The parallel molecular evolution of the VirB/Bep system displays a striking example of a key innovation involved in independent adaptive processes and the emergence of bacterial pathogens

  3. Generation IV nuclear energy systems and hydrogen economy. New progress in the energy field in the 21st century

    International Nuclear Information System (INIS)

    Zang Mingchang

    2004-01-01

    The concept of hydrogen economy was initiated by the United States and other developed countries in the turn of the century to mitigate anxiety of national security due to growing dependence on foreign sources of energy and impacts on air quality and the potential effects of greenhouse gas emissions. Hydrogen economy integrates the primary energy used to produce hydrogen as a future energy carrier, hydrogen technologies including production, delivery and storage, and various fuel cells for transportation and stationary applications. A new hydrogen-based energy system would created as an important solution in the 21st century, flexible, affordable, safe, domestically produced, used in all sectors of the economy and in all regions of the country, if all the R and D plans and the demonstration come to be successful in 20-30 years. Among options of primary energy. Generation IV nuclear energy under development is particularly well suited to hydrogen production, offering the competitive position of large-scale hydrogen production with near-zero emissions. (author)

  4. Protein homology network families reveal step-wise diversification of Type III and Type IV secretion systems.

    Directory of Open Access Journals (Sweden)

    Duccio Medini

    2006-12-01

    Full Text Available From the analysis of 251 prokaryotic genomes stored in public databases, the 761,260 deduced proteins were used to reconstruct a complete set of bacterial proteic families. Using the new Overlap algorithm, we have partitioned the Protein Homology Network (PHN, where the proteins are the nodes and the links represent homology relationships. The algorithm identifies the densely connected regions of the PHN that define the families of homologous proteins, here called PHN-Families, recognizing the phylogenetic relationships embedded in the network. By direct comparison with a manually curated dataset, we assessed that this classification algorithm generates data of quality similar to a human expert. Then, we explored the network to identify families involved in the assembly of Type III and Type IV secretion systems (T3SS and T4SS. We noticed that, beside a core of conserved functions (eight proteins for T3SS, seven for T4SS, a variable set of accessory components is always present (one to nine for T3SS, one to five for T4SS. Each member of the core corresponds to a single PHN-Family, while accessory proteins are distributed among different pure families. The PHN-Family classification suggests that T3SS and T4SS have been assembled through a step-wise, discontinuous process, by complementing the conserved core with subgroups of nonconserved proteins. Such genetic modules, independently recruited and probably tuned on specific effectors, contribute to the functional specialization of these organelles to different microenvironments.

  5. Trends in prescribing systemic treatment and overall survival for non-small cell lung cancer stage IIIB/IV in the Netherlands : 2008-2012

    NARCIS (Netherlands)

    Peters, Bas J M; Cramer-Vd Welle, Christine M; Smit, Arthur A J; Schramel, Franz M N H; van de Garde, Ewoudt M W

    2017-01-01

    BACKGROUND: The present study aims to give a detailed overview of day-to-day practice in the systemic treatment of NSCLC stage IIIB/IV and its clinical outcomes in six large teaching hospitals in the Netherlands in the period 2008-2012. METHODS: A retrospective observational cohort study was

  6. A comparison of outcomes according to different diagnostic systems for delirium (DSM-5, DSM-IV, CAM, and DRS-R98).

    Science.gov (United States)

    Adamis, Dimitrios; Meagher, David; Rooney, Siobhan; Mulligan, Owen; McCarthy, Geraldine

    2018-04-01

    ABSTRACTStudies indicate that DSM-5 criteria for delirium are relatively restrictive, and identify different cases of delirium compared with previous systems. We evaluate four outcomes of delirium (mortality, length of hospital stay, institutionalization, and cognitive improvement) in relation to delirium defined by different DSM classification systems.Prospective, longitudinal study of patients aged 70+ admitted to medical wards of a general hospital. Participants were assessed up to a maximum of four times during two weeks, using DSM-5 and DSM-IV criteria, DRS-R98 and CAM scales as proxies for DSM III-R and DSM III.Of the 200 assessed patients (mean age 81.1, SD = 6.5; and 50% female) during hospitalization, delirium was identified in 41 (20.5%) using DSM-5, 45 (22.5%) according to DSM-IV, 46 (23%) with CAM positive, and 37 (18.5%) with DRS-R98 severity score >15. Mortality was significantly associated with delirium according to any classification system, but those identified with DSM-5 were at greater risk. Length of stay was significantly longer for those with DSM-IV delirium. Discharge to a care home was associated only with DRS-R98 defined delirium. Cognitive improvement was only associated with CAM and DSM-IV. Different classification systems for delirium identify populations with different outcomes.

  7. Diffuse reticuloendothelial system involvement in type IV glycogen storage disease with a novel GBE1 mutation: a case report and review.

    Science.gov (United States)

    Magoulas, Pilar L; El-Hattab, Ayman W; Roy, Angshumoy; Bali, Deeksha S; Finegold, Milton J; Craigen, William J

    2012-06-01

    Glycogen storage disease type IV is a rare autosomal recessive disorder of glycogen metabolism caused by mutations in the GBE1 gene that encodes the 1,4-alpha-glucan-branching enzyme 1. Its clinical presentation is variable, with the most common form presenting in early childhood with primary hepatic involvement. Histologic manifestations in glycogen storage disease type IV typically consist of intracytoplasmic non-membrane-bound inclusions containing abnormally branched glycogen (polyglucosan bodies) within hepatocytes and myocytes. We report a female infant with classic hepatic form of glycogen storage disease type IV who demonstrated diffuse reticuloendothelial system involvement with the spleen, bone marrow, and lymph nodes infiltrated by foamy histiocytes with intracytoplasmic polyglucosan deposits. Sequence analysis of the GBE1 gene revealed compound heterozygosity for a previously described frameshift mutation (c.1239delT) and a novel missense mutation (c.1279G>A) that is predicted to alter a conserved glycine residue. GBE enzyme analysis revealed no detectable activity. A review of the literature for glycogen storage disease type IV patients with characterized molecular defects and deficient enzyme activity reveals most GBE1 mutations to be missense mutations clustering in the catalytic enzyme domain. Individuals with the classic hepatic form of glycogen storage disease type IV tend to be compound heterozygotes for null and missense mutations. Although the extensive reticuloendothelial system involvement that was observed in our patient is not typical of glycogen storage disease type IV, it may be associated with severe enzymatic deficiency and a poor outcome. Copyright © 2012 Elsevier Inc. All rights reserved.

  8. Computational prediction of secretion systems and secretomes of Brucella: identification of novel type IV effectors and their interaction with the host.

    Science.gov (United States)

    Sankarasubramanian, Jagadesan; Vishnu, Udayakumar S; Dinakaran, Vasudevan; Sridhar, Jayavel; Gunasekaran, Paramasamy; Rajendhran, Jeyaprakash

    2016-01-01

    Brucella spp. are facultative intracellular pathogens that cause brucellosis in various mammals including humans. Brucella survive inside the host cells by forming vacuoles and subverting host defence systems. This study was aimed to predict the secretion systems and the secretomes of Brucella spp. from 39 complete genome sequences available in the databases. Furthermore, an attempt was made to identify the type IV secretion effectors and their interactions with host proteins. We predicted the secretion systems of Brucella by the KEGG pathway and SecReT4. Brucella secretomes and type IV effectors (T4SEs) were predicted through genome-wide screening using JVirGel and S4TE, respectively. Protein-protein interactions of Brucella T4SEs with their hosts were analyzed by HPIDB 2.0. Genes coding for Sec and Tat pathways of secretion and type I (T1SS), type IV (T4SS) and type V (T5SS) secretion systems were identified and they are conserved in all the species of Brucella. In addition to the well-known VirB operon coding for the type IV secretion system (T4SS), we have identified the presence of additional genes showing homology with T4SS of other organisms. On the whole, 10.26 to 14.94% of total proteomes were found to be either secreted (secretome) or membrane associated (membrane proteome). Approximately, 1.7 to 3.0% of total proteomes were identified as type IV secretion effectors (T4SEs). Prediction of protein-protein interactions showed 29 and 36 host-pathogen specific interactions between Bos taurus (cattle)-B. abortus and Ovis aries (sheep)-B. melitensis, respectively. Functional characterization of the predicted T4SEs and their interactions with their respective hosts may reveal the secrets of host specificity of Brucella.

  9. Using NASA`s Airborne Topographic Mapper IV to Quantify Geomorphic Change in Arid Southwestern Stream Systems

    Science.gov (United States)

    Finnegan, D. C.; Krabill, W.; Lichvar, R. W.; Ericsson, M. P.; Frederick, E.; Manizade, S.; Yungel, J.; Sonntag, J.; Swift, R.

    2005-12-01

    Understanding how arid stream systems respond to individual climatic events is often difficult given the dynamic and `flashy' nature of most watersheds and the unpredictable nature of individual storm events. Until recently conventional methods for quantifying change dictated the use of stream gauge measurements coupled with periodic cross-section measurements to quantify changes in large-scale channel geometry. Using this approach to quantify change across large areas often proves to be impractical and unattainable given the laborious nature of most surveying techniques including modern GPS systems. Alternately, airborne laser technologies such as NASA's Airborne Topographic Mapper (ATM) are capable of quantifying small-scale changes (~5-10cm) across large-scale terrain rapidly and accurately. The ATM was developed at the NASA-GSFC Wallops Flight Facility. Its current version, ATM-4, measures topography 5,000 times per second across a 45-degree swath below the aircraft by transmitting a 532nm (green) laser pulse and receiving the backscattered signal in a high-speed waveform digitizer. The laser range measurements are combined with aircraft location from GPS and attitude from an inertial navigation system (INS) to provide a precise XYZ coordinate for each (~1-meter diameter) laser footprint on the ground. Our work focuses on the use of airborne laser altimetry to quantify the nature of individual surfaces and the geomorphic change that occurs within small arid stream systems during significant storm events. In September of 2003 and 2005 acquisition surveys using NASA's ATM-IV were flown over Mission Creek, a small arid stream system in Southern California's Mojave Desert with a relatively long gauging history (>40yrs), allowing us to quantify the geomorphic change occurring within the channel as a result of the record storm events during the winter of 2004-2005. Preliminary results associated with our work are encouraging and lead us to believe that when compared

  10. Viewpoint: Central adjudication of myocardial infarction in outcome-driven clinical trials--common patterns in TRITON, RECORD, and PLATO?

    Science.gov (United States)

    Serebruany, Victor L; Atar, Dan

    2012-09-01

    Central adjudication in randomised controlled outcome-driven trials represents a traditional approach to maintain data integrity by applying uniformed rules for assessment of clinical events. It was the purpose of this investigation to determine the patterns of myocardial infarction (MI) adjudication in the TRITON, RECORD, and PLATO trials. We were matching centrally-adjudicated MI's (CAMI's) from the official trial publication with the site-reported MI (SRMI's) count from the Food and Drug Administration's secondary analyses for the investigational compounds prasugrel (TRITON), rosiglitazone (RECORD), and ticagrelor (PLATO). CAMI numbers showed a remarkable discrepancy to SRMI's by more than a doubling of the difference: from 72 to 145 events in TRITON favoring prasugrel (from a hazard ratio [HR]=0.76, p=0.08; to a HR=0.76, p<0.001), and from 44 to 89 events in favour of ticagrelor in PLATO (from a HR=0.94, p=0.095; to a HR=0.84, p<0.001). In contrast, in the RECORD trial, the CAMI count was less than the SRMI count (from 24 to 8 events, from a HR=1.42, p=0.93; to a HR=1.14, p=0.96), in this case diminishing cardiovascular hazards in favour of rosiglitazone. In conclusion, central adjudication in the TRITON, the RECORD, and the PLATO trial turned out to have a critical impact on study outcomes. Trial publications should in the future include site-reported major efficacy and safety endpoints to preserve data integrity. The regulatory authorities should consider independent audits when there is a major disagreement between centrally adjudicated and site reported events influencing the results of a major clinical trial.

  11. Development and characterization of the control assembly system for the large 2400 MWth Generation IV gas-cooled fast reactor

    International Nuclear Information System (INIS)

    Girardin, G.; Rimpault, G.; Morin, F.; Bosq, J.C.; Coddington, P.; Mikityuk, K.; Chawla, R.

    2008-01-01

    The present paper is related to the design and neutronic characterization of the principal control assembly system for the reference large (2400 MWth) Generation IV gas-cooled fast reactor (GFR), which makes use of ceramic-ceramic (CERCER) plate-type fuel-elements with (U-Pu) carbide fuel contained within a SiC inert matrix. For the neutronic calculations, the deterministic code system ERANOS-2.0 has been used, in association with a full core model including a European fast reactor (EFR)-type pattern for the control assemblies as a starting point. More specifically, the core contains a total of 33 control (control system device: CSD) and safety (diverse safety device: DSD) assemblies implemented in three banks. In the design of the new control assembly system, particular attention was given to the heat generation within the assemblies, so that both neutronic and thermal-hydraulic constraints could be appropriately accounted for. The thermal-hydraulic calculations have been performed with the code COPERNIC, significant coolant mass flow rates being found necessary to maintain acceptable cladding temperatures of the absorber pins. Complementary to the design study, neutronic investigations have been performed to assess the impact of the control assemblies in the GFR core in greater detail (rod interactions, shift of the flux, peaking factors, etc.). Thus, considerable shadowing effects have been observed between the first bank and the safety bank, as also between individual assemblies within the first bank. Large anti-shadowing effects also occur, the most prominent being that between the two CSD banks, where the total assembly worth is almost doubled in comparison to the sum of the individual values. Additional investigations have been performed and, in this context, it has been found that computation of the first-order eigenvalue and the eigenvalue separation is a robust tool to anticipate control assembly interactions in a large fast-spectrum core. One interesting

  12. Peptide Nucleic Acid Knockdown and Intra-host Cell Complementation of Ehrlichia Type IV Secretion System Effector

    Directory of Open Access Journals (Sweden)

    Pratibha Sharma

    2017-06-01

    Full Text Available Survival of Ehrlichia chaffeensis depends on obligatory intracellular infection. One of the barriers to E. chaffeensis research progress has been the inability, using conventional techniques, to generate knock-out mutants for genes essential for intracellular infection. This study examined the use of Peptide Nucleic Acids (PNAs technology to interrupt type IV secretion system (T4SS effector protein expression in E. chaffeensis followed by intracellular complementation of the effector to determine its requirement for infection. Successful E. chaffeensis infection depends on the E. chaffeensis-specific T4SS protein effector, ehrlichial translocated factor-1 (Etf-1, which induces Rab5-regulated autophagy to provide host cytosolic nutrients required for E. chaffeensis proliferation. Etf-1 is also imported by host cell mitochondria where it inhibits host cell apoptosis to prolong its infection. We designed a PNA specific to Etf-1 and showed that the PNA bound to the target region of single-stranded Etf-1 RNA using a competitive binding assay. Electroporation of E. chaffeensis with this PNA significantly reduced Etf-1 mRNA and protein, and the bacteria's ability to induce host cell autophagy and infect host cells. Etf-1 PNA-mediated inhibition of ehrlichial Etf-1 expression and E. chaffeensis infection could be intracellularly trans-complemented by ectopic expression of Etf-1-GFP in host cells. These data affirmed the critical role of bacterial T4SS effector in host cell autophagy and E. chaffeensis infection, and demonstrated the use of PNA to analyze the gene functions of obligate intracellular bacteria.

  13. Study on the electrolytic reduction of Uranium-VI to Uranium-IV in a nitrate system

    International Nuclear Information System (INIS)

    Araujo, B.F. de; Almeida, S.G. de; Forbicini, S.; Matsuda, H.T.; Araujo, J.A. de.

    1981-05-01

    The determination of the best conditions to prepare hydrazine stabilized uranium (IV) nitrate solutions for utilization in Purex flowsheets is dealt with. Electrolytic reduction of U(VI) has been selected as the basic method, using an open electrolytic cell with titanum and platinum electrodes. The hydrazine concentration, the current density, acidity, U(VI) concentration and reduction time were the parameters studied and U(IV)/U(VI) ratio was used to evaluate the degree of reduction. From the results it could be concluded that the technique is reliable. The U(IV) solutions remains constant for at least two weeks and can be used in the chemical processing of irradiated uranium fuels. (Author) [pt

  14. Type-IVC Secretion System: A Novel Subclass of Type IV Secretion System (T4SS) Common Existing in Gram-Positive Genus Streptococcus

    Science.gov (United States)

    Chen, Chen; Gao, George F.

    2012-01-01

    A growing number of pathogens are being found to possess specialized secretion systems which they use in various ways to subvert host defenses. Type IV secretion system (T4SS) is one of versatile secretion systems essential for the virulence and even survival of some bacteria species, and they enable the secretion of protein and DNA substrates across the cell envelope. T4SS was once believed to be present only in Gram-negative bacteria. In this study, we present evidence of a new subclass of T4SS, Type-IVC secretion system and indicate its common existence in the Gram-positive bacterial genus Streptococcus. We further identified that VirB1, VirB4, VirB6 and VirD4 are the minimal key components of this system. Using genome comparisons and evolutionary relationship analysis, we proposed that Type-IVC secretion system is movable via transposon factors and mediates the conjugative transfer of DNA, enhances bacterial pathogenicity, and could cause large-scale outbreaks of infections in humans. PMID:23056296

  15. From Pericles to Plato – from democratic political praxis to totalitarian political philosophy

    Directory of Open Access Journals (Sweden)

    Øjvind Larsen

    2012-03-01

    Full Text Available Plato is normally taken as one of the founders of Western political philosophy, not at least with his Republic. Here, he constructs a hierarchy of forms of governments, beginning with aristocracy at the top as a critical standard for the other forms of governments, and proceeding through timocracy and oligarchy to democracy and tyranny at the bottom. Following Karl Popper, the paper argues that Plato’s is a totalitarian philosophy that emphasizes the similarities between democracy and tyranny, which it considers to be the two worst forms of government. Plato’s denigration of democracy has dominated the tradition of political philosophy until recent times. This paper, however, shows that political philosophy in fact originates in democracy, especially as developed by the sophists and that philosophy is only a form of sophism with a similar origin in ancient Greek democracy. A discussion of Pericles’ funeral oration is used to show that Pericles presented a democratic political philosophy that can serve as a counterpoint to Plato’s political philosophy in the Republic.

  16. Thermodynamic description of Tc(iv) solubility and carbonate complexation in alkaline NaHCO3-Na2CO3-NaCl systems.

    Science.gov (United States)

    Baumann, A; Yalçıntaş, E; Gaona, X; Polly, R; Dardenne, K; Prüßmann, T; Rothe, J; Altmaier, M; Geckeis, H

    2018-03-28

    The solubility of 99 Tc(iv) was investigated in dilute to concentrated carbonate solutions (0.01 M ≤ C tot ≤ 1.0 M, with C tot = [HCO 3 - ] + [CO 3 2- ]) under systematic variation of ionic strength (I = 0.3-5.0 M NaHCO 3 -Na 2 CO 3 -NaCl-NaOH) and pH m (-log[H + ] = 8.5-14.5). Strongly reducing conditions (pe + pH m ≈ 2) were set with Sn(ii). Carbonate enhances the solubility of Tc(iv) in alkaline conditions by up to 3.5 log 10 -units compared to carbonate-free systems. Solvent extraction and XANES confirmed that Tc was kept as +IV during the timeframe of the experiments (≤ 650 days). Solid phase characterization performed by XAFS, XRD, SEM-EDS, chemical analysis and TG-DTA confirmed that TcO 2 ·0.6H 2 O(am) controls the solubility of Tc(iv) under the conditions investigated. Slope analysis of the solubility data in combination with solid/aqueous phase characterization and DFT calculations indicate the predominance of the species Tc(OH) 3 CO 3 - at pH m ≤ 11 and C tot ≥ 0.01 M, for which thermodynamic and activity models are derived. Solubility data obtained above pH m ≈ 11 indicates the formation of previously unreported Tc(iv)-carbonate species, possibly Tc(OH) 4 CO 3 2- , although the likely formation of additional complexes prevents deriving a thermodynamic model valid for this pH m -region. This work provides the most comprehensive thermodynamic dataset available for the system Tc 4+ -Na + -Cl - -OH - -HCO 3 - -CO 3 2- -H 2 O(l) valid under a range of conditions relevant for nuclear waste disposal.

  17. Safety approach and research and development presentation for the selected systems of the International forum Generation IV

    International Nuclear Information System (INIS)

    Fiorini, G.L.

    2003-01-01

    This paper deals with the six projects of the Generation IV forum: Sodium Fast reactor, lead fast reactor, gas fast reactor, very high temperature reactor, supercritical water reactor, molten salt reactor. The technical objectives of the reactor safety and the design/evaluation approach are discussed. (A.L.B.)

  18. Gens Fera. The Wild men in the system of border decoration of the Bible of Wenceslas IV

    Czech Academy of Sciences Publication Activity Database

    Studničková, Milada

    2014-01-01

    Roč. 62, č. 3 (2014), s. 214-239 ISSN 0049-5123 R&D Projects: GA ČR GA13-39192S Institutional support: RVO:68378033 Keywords : book illumination * Bible of Wenceslas IV Subject RIV: AL - Art, Architecture, Cultural Heritage http://www.umeni-art.cz/admin/fileGet.aspx?v=issue-issue-2267-category-2268-paragraph-2269-pdf&l=cz

  19. Status of the design and safety project for the sodium-cooled fast reactor as a generation IV nuclear energy system

    International Nuclear Information System (INIS)

    Niwa, Hajime; Fiorini, Gian-Luigi; Sim, Yoon-Sub; Lennox, Tom; Cahalan, James E.

    2005-01-01

    The Design and Safety Project Management Board (DSPMB) was established under the Sodium Cooled Fast Reactor (SFR) System Steering Committee (SSC) in the Generation IV international Forum. The DSPMB will promote collaborative R and D activities on reactor core design, and safety assessment for candidate systems, and also integrate these results together with those from other PMBs such as advanced fuel and component to a whole fast reactor system in order to develop high performance systems that will satisfy the goals of Generation IV nuclear energy systems. The DSPMB has formulated the present R and D schedules for this purpose. Two SFR concepts were proposed: a loop-type system with primarily a MOX fuel core and a pool-type system with a metal fuel core. Study of innovative systems and their evaluation will also be included. The safety project will cover both the safety assessment of the design and the preparation of the methods/tools to be used for the assessment. After a rather short viability phase, the project will move to the performance phase for development of performance data and design optimization of conceptual designs. This paper describes the schedules, work packages and tasks for the collaborative studies of the member countries. (author)

  20. MODERATE C IV ABSORBER SYSTEMS REQUIRE 10{sup 12} M{sub Sun} DARK MATTER HALOS AT z {approx} 2.3: A CROSS-CORRELATION STUDY OF C IV ABSORBER SYSTEMS AND QUASARS IN SDSS-III BOSS DR9

    Energy Technology Data Exchange (ETDEWEB)

    Vikas, Shailendra; Wood-Vasey, W. Michael [Pittsburgh Particle Physics, Astrophysics, and Cosmology Center (PITT PACC), Department of Physics and Astronomy, University of Pittsburgh, Pittsburgh, PA 15260 (United States); Lundgren, Britt [Department of Physics, Yale University, New Haven, CT 06511 (United States); Ross, Nicholas P. [Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 92420 (United States); Myers, Adam D. [Department of Physics and Astronomy, University of Wyoming, Laramie, WY 82071 (United States); AlSayyad, Yusra [Department of Astronomy, University of Washington, Seattle, WA 98195 (United States); York, Donald G. [Department of Astronomy, University of Chicago, 5640 S. Ellis Ave, Chicago, IL 60637 (United States); Schneider, Donald P. [Department of Astronomy and Astrophysics, Pennsylvania State University, University Park, PA 16802 (United States); Brinkmann, J.; Bizyaev, Dmitry; Brewington, Howard; Malanushenko, Elena; Malanushenko, Viktor; Oravetz, Daniel; Pan, Kaike; Snedden, Stephanie [Apache Point Observatory, P.O. Box 59, Sunspot, NM 88349-0059 (United States); Ge, Jian [Department of Astronomy, University of Florida, Gainesville, FL 32611 (United States); Muna, Demitri [Center for Cosmology and Particle Physics, New York University, New York, NY 10003 (United States); Paris, Isabelle; Petitjean, Patrick, E-mail: skv4@pitt.edu [UPMC-CNRS, UMR7095, Institut d' Astrophysique de Paris, F-75014 Paris (France); and others

    2013-05-01

    We measure the two-point cross-correlation function of C IV absorber systems and quasars, using spectroscopic data from the Sloan Digital Sky Survey III Baryon Oscillation Spectroscopic Survey (BOSS; Data Release 9). The 19,701 quasars and 6149 C IV ''moderate'' absorbers, 0.28 A < rest-frame equivalent width (EW) < 5 A, in our study cover a redshift range of 2.1 < z < 2.5 over 3300 deg{sup 2} and represent a factor of two increase in sample size over previous investigations. We find a correlation scale length and slope of the redshift-space cross-correlation function of s{sub 0} = 8.46 {+-} 1.24 Mpc, {gamma} = 1.68 {+-} 0.19, in the redshift-space range 10 < s < 100 Mpc. We find a projected cross-correlation function of C IV absorption systems and quasars of r{sub 0} = 7.76 {+-} 2.80 Mpc, {gamma} = 1.74 {+-} 0.21. We measure the combined quasar and C IV bias to be b{sub QSO} b{sub C{sub IV}} = 8.81 {+-} 2.28. Using an estimate of b{sub QSO} from the quasar auto-correlation function we find b{sub CIV} = 2.38 {+-} 0.62. This b{sub CIV} implies that EW > 0.28 A C IV absorbers at z {approx} 2.3 are typically found in dark matter halos that have masses {>=}10{sup 11.3}-10{sup 13.4} M{sub Sun} at that redshift. The complete BOSS sample will triple the number of both quasars and absorption systems and increase the power of this cross-correlation measurement by a factor of two.

  1. CagI is an essential component of the Helicobacter pylori Cag type IV secretion system and forms a complex with CagL.

    Directory of Open Access Journals (Sweden)

    Kieu Thuy Pham

    Full Text Available Helicobacter pylori, the causative agent of type B gastritis, peptic ulcers, gastric adenocarcinoma and MALT lymphoma, uses the Cag type IV secretion system to induce a strong proinflammatory response in the gastric mucosa and to inject its effector protein CagA into gastric cells. CagA translocation results in altered host cell gene expression profiles and cytoskeletal rearrangements, and it is considered as a major bacterial virulence trait. Recently, it has been shown that binding of the type IV secretion apparatus to integrin receptors on target cells is a crucial step in the translocation process. Several bacterial proteins, including the Cag-specific components CagL and CagI, have been involved in this interaction. Here, we have examined the localization and interactions of CagI in the bacterial cell. Since the cagI gene overlaps and is co-transcribed with the cagL gene, the role of CagI for type IV secretion system function has been difficult to assess, and conflicting results have been reported regarding its involvement in the proinflammatory response. Using a marker-free gene deletion approach and genetic complementation, we show now that CagI is an essential component of the Cag type IV secretion apparatus for both CagA translocation and interleukin-8 induction. CagI is distributed over soluble and membrane-associated pools and seems to be partly surface-exposed. Deletion of several genes encoding essential Cag components has an impact on protein levels of CagI and CagL, suggesting that both proteins require partial assembly of the secretion apparatus. Finally, we show by co-immunoprecipitation that CagI and CagL interact with each other. Taken together, our results indicate that CagI and CagL form a functional complex which is formed at a late stage of secretion apparatus assembly.

  2. Love and/in psychoanalysis: a commentary on Lacan's reading of Plato's Symposium in Seminar VIII: Transference.

    Science.gov (United States)

    Fink, Bruce

    2015-02-01

    What is love and what part does it play in psychoanalysis? Where are the analyst and the analysand situated in relation to the roles defined as those of the "lover" and the "beloved"? Jacques Lacan explores these and other questions in his soon-to-be-published Seminar VIII: Transference by providing an extensive commentary on Plato's most famous dialogue on love, the Symposium. This paper outlines some of the major points about love that grow out of Lacan's reading of the dialogue and examines their relevance to the analytic setting. Can the analyst be characterized as a sort of modern-day Socrates?

  3. Ancient philosophical ideas of the soul (Plato-Aristotelian tradition and Stoicism as a source of Patristic Thought

    Directory of Open Access Journals (Sweden)

    Zaitsev Cornelius

    2014-10-01

    Full Text Available The article discusses the ancient idea of the soul that in the patristic era has been enriched by the perception of the methodology of ancient philosophy. Greek and Roman thinkers considered some properties of the soul, its immortality, revealed its “levels and strata” (Plato, Aristotle, expressed first guesses about the nature of sinful passions (the Stoics. But some aspects still remained unresolved so far. This is the issue of materiality or immateriality, of the soul, which "raised" in the Russian Empire in the 19th century (the dispute saints Theophan the Recluse and Ignatius Brianchaninov and remains relevant today.

  4. IV treatment at home

    Science.gov (United States)

    ... Other IV treatments you may receive after you leave the hospital include: Treatment for hormone deficiencies Medicines for severe nausea that cancer chemotherapy or pregnancy may cause Patient-controlled analgesia (PCA) for pain (this is IV ...

  5. [Plato's conceptions of disorders of the soul (Ta peri psuchên nosêmata). Timaeus as the beginning of a dynamic and ethic psychopathology].

    Science.gov (United States)

    Godderis, J

    1998-01-01

    This contribution to the study of the evolution of fundamental concepts in psychiatry, and in particular of the interpretative models of mental disease, focuses on Plato's conceptions concerning the "disorders of the soul". Plato's "psychopathological" work suggests the decline of an hereditary conglomeration of interpretative arrangements of the irrational phenomena related to mental disease which, corresponding to the social needs of that time, had been united by the belief in myth and its therapeutic value. These archaic religious conceptions have most certainly been reversed by Plato, especially in his Timaeus, one of the three most influential of his dialogues. In a notable passage in this cosmological dialogue (86b ff.) Plato treats of those diseases of the soul which are caused by things physical, whether this be a "defective bodily constitution" or "faulty education". The diseases of the soul are thus no longer considered having a divine origin. Mental diseases to which man is unwittingly subject by defects in birth or education concern himself and his inner life and they cannot be dismissed with simplistic allegories. According to Plato they originate from a conflict, supported by a secret, hidden, irrational "self" that has its roots in the sôma, the rational "self" being only able to recuperate its total integrity if it manages, through self-discipline and knowledge, to check the somatic impulses, the folly of the body. Also, Plato offers a series of remedies to correct the undue influence of body on soul and soul on body, with a view to instituting a right balance and proportion between them. This, together with a stress on "care of the soul", particularly of the divine and immortal element, implicitly assumes that it is in man's power to apply the necessary remedies to himself and effect some sort of readjustment.

  6. PRECIOUS METALS IN SDSS QUASAR SPECTRA. I. TRACKING THE EVOLUTION OF STRONG, 1.5 < z < 4.5 C IV ABSORBERS WITH THOUSANDS OF SYSTEMS

    International Nuclear Information System (INIS)

    Cooksey, Kathy L.; Kao, Melodie M.; Simcoe, Robert A.; O'Meara, John M.; Prochaska, J. Xavier

    2013-01-01

    We have vastly increased the C IV statistics at intermediate redshift by surveying the thousands of quasars in the Sloan Digital Sky Survey (SDSS) Data-Release 7. We visually verified over 16,000 C IV systems with 1.46 r ≈ 0.6 Å. We analyzed the sample as a whole and in 10 small redshift bins with approximately 1500 doublets each. The equivalent width frequency distributions f(W r ) were well modeled by an exponential, with little evolution in shape. In contrast with previous studies that modeled the frequency distribution as a single power law, the fitted exponential gives a finite mass density for the C IV ions. The comoving line density dN CIV /dX evolved smoothly with redshift, increasing by a factor of 2.37 ± 0.09 from z = 4.55-1.96, then plateauing at dN CIV /dX∼0.34 for z = 1.96-1.46. Comparing our SDSS sample with z 5 (infrared) surveys, we see an approximately 10-fold increase in dN CIV /dX over z ≈ 6 → 0, for W r ≥ 0.6 Å. This suggests a monotonic and significant increase in the enrichment of gas outside galaxies over the 12 Gyr lifetime of the universe.

  7. How the 2SLS/IV estimator can handle equality constraints in structural equation models: a system-of-equations approach.

    Science.gov (United States)

    Nestler, Steffen

    2014-05-01

    Parameters in structural equation models are typically estimated using the maximum likelihood (ML) approach. Bollen (1996) proposed an alternative non-iterative, equation-by-equation estimator that uses instrumental variables. Although this two-stage least squares/instrumental variables (2SLS/IV) estimator has good statistical properties, one problem with its application is that parameter equality constraints cannot be imposed. This paper presents a mathematical solution to this problem that is based on an extension of the 2SLS/IV approach to a system of equations. We present an example in which our approach was used to examine strong longitudinal measurement invariance. We also investigated the new approach in a simulation study that compared it with ML in the examination of the equality of two latent regression coefficients and strong measurement invariance. Overall, the results show that the suggested approach is a useful extension of the original 2SLS/IV estimator and allows for the effective handling of equality constraints in structural equation models. © 2013 The British Psychological Society.

  8. Wolbachia lipoproteins: abundance, localisation and serology of Wolbachia peptidoglycan associated lipoprotein and the Type IV Secretion System component, VirB6 from Brugia malayi and Aedes albopictus.

    Science.gov (United States)

    Voronin, Denis; Guimarães, Ana F; Molyneux, Gemma R; Johnston, Kelly L; Ford, Louise; Taylor, Mark J

    2014-10-06

    Lipoproteins are the major agonists of Wolbachia-dependent inflammatory pathogenesis in filariasis and a validated target for drug discovery. Here we characterise the abundance, localisation and serology of the Wolbachia lipoproteins: Wolbachia peptidoglycan associated lipoprotein and the Type IV Secretion System component, VirB6. We used proteomics to confirm lipoprotein presence and relative abundance; fractionation, immunoblotting and confocal and electron immuno-microscopy for localisation and ELISA for serological analysis. Proteomic analysis of Brugia malayi adult female protein extracts confirmed the presence of two lipoproteins, previously predicted through bioinformatics: Wolbachia peptidoglycan associated lipoprotein (wBmPAL) and the Type IV Secretion System component, VirB6 (wBmVirB6). wBmPAL was among the most abundant Wolbachia proteins present in an extract of adult female worms with wBmVirB6 only detected at a much lower abundance. This differential abundance was reflected in the immunogold-labelling, which showed wBmPAL localised at numerous sites within the bacterial membranes, whereas wBmVirB6 was present as a single cluster on each bacterial cell and also located within the bacterial membranes. Immunoblotting of fractionated extracts confirmed the localisation of wBmPAL to membranes and its absence from cytosolic fractions of C6/36 mosquito cells infected with wAlbB. In whole worm mounts, antibody labelling of both lipoproteins were associated with Wolbachia. Serological analysis showed that both proteins were immunogenic and raised antibody responses in the majority of individuals infected with Wuchereria bancrofti. Two Wolbachia lipoproteins, wBmPAL and wBmVirB6, are present in extracts of Brugia malayi with wBmPAL among the most abundant of Wolbachia proteins. Both lipoproteins localised to bacterial membranes with wBmVirB6 present as a single cluster suggesting a single Type IV Secretory System on each Wolbachia cell.

  9. A spectroscopic search for colliding stellar winds in O-type close binary systems. IV - Iota Orionis

    Science.gov (United States)

    Gies, Douglas R.; Wiggs, Michael S.; Bagnuolo, William G., Jr.

    1993-01-01

    We present H-alpha and He I 6678 A line profiles for the eccentric orbit binary Iota Ori. We have applied a tomography algorithm which uses the established orbital velocity curves and intensity ratio to reconstruct the spectral line profiles for each star. The He I profiles appear as pure photospheric lines, and H-alpha shows variable emission in the line core throughout the orbit (which is typical of O giants) and in the blue wing near periastron passage. We show that the blue wing emission is consistent with an origin between the stars which probably results from a dramatic focusing of the primary's stellar wind at periastron. We also present IUE archival spectra of the UV wind lines N V 1240 A and C IV 1550 A.

  10. Validation of the Monte Carlo criticality program KENO IV and the Hansen-Roach sixteen-energy-group-cross sections for high-assay uranium systems

    International Nuclear Information System (INIS)

    Handley, G.R.; Masters, L.C.; Stachowiak, R.V.

    1981-01-01

    Validation of the Monte Carlo criticality code, KENO IV, and the Hansen-Roach sixteen-energy-group cross sections was accomplished by calculating the effective neutron multiplication constant, k/sub eff/, of 29 experimentally critical assemblies which had uranium enrichments of 92.6% or higher in the uranium-235 isotope. The experiments were chosen so that a large variety of geometries and of neutron energy spectra were covered. Problems, calculating the k/sub eff/ of systems with high-uranium-concentration uranyl nitrate solution that were minimally reflected or unreflected, resulted in the separate examination of five cases

  11. A display model for the TOU of PLATO: just a cool toy or a benchmark of opportunities?

    Science.gov (United States)

    Dima, M.; Greggio, D.; Bergomi, M.; Biondi, F.; Farinato, J.; Farisato, G.; Magrin, D.; Lessio, L.; Marafatto, L.; Munari, M.; Pagano, I.; Ragazzoni, R.; Viotto, V.; Piazza, D.

    2016-07-01

    We produced a "toy-model" of one Telescope Optical Unit of PLATO, the Medium sized mission selected by ESA to fly in 2024. This is a six lenses dioptric very wide field camera with a window in front to take care of radiation impact on the first lens whose optical glass cannot be replaced with a radiation hardened one. The main aim of this project is just to produce a "cool" model for display purposes, in which one can "explore" the details of the inside through some openings in the tube, in order to visually inspect some of the fine details of the opto-mechanics. While its didactic and advertising role is out of doubt, during its construction we realized that some interesting outcome can be of some relevance for the project itself and that some findings could be useful, in order to assess the ability of producing with the same technology some (of course of much more modest quality) optical systems. In this context, we immediately dropped the option of producing the lenses with opaque material painted with a color resembling a refractive material (like blue for instance) and decided to actually produce them with transparent plastic. Furthermore the surfaces are then finely polished in order to give them basic optical properties. Such an optical system has only very coarsely the converging properties of the original nominal design for a number of reasons: the refractive indexes are not the nominal ones, the quality of the surfaces and their nominal values are only roughly, within a few percent, the targeted one, and the way the surfaces are built up makes them prone to some diffraction effects. However, the bulk of the lens and the surface roughness will give a large magnification of the scattering effects that will be experienced, at a much lower level, on the actual flight model. We investigated through propagation of a laser beam and by digital camera the main stray light modes that this toymodel offers. In other words, the model amplifies, to a large extent, the

  12. Investigation on a Sensitive Chemiluminescence System Based on Ni(IV Complex to Determine Two β2-Agonist Drugs in Urine and Swine Feed and Their Mechanism

    Directory of Open Access Journals (Sweden)

    Xiao Dong

    2018-04-01

    Full Text Available Veterinary drug residues, particularly traces of β2-agonists, can cause various kinds of harmful impact to the environment and public health. Here, a sensitive chemiluminescence (CL method incorporated with a flow injection analysis is developed for the determination of two β2-agonists [i.e., salbutamol (SAL and terbutaline (TEB]. The system is based on the CL reaction of Ni(IV complex with luminol in alkaline solutions, whereas SAL and TEB can significantly enhance CL intensities. Under optimum conditions, CL intensities are proportional to the SAL and TEB concentration in the range of 1.0 × 10−9 M to 5.0 × 10−7 M and 1.0 × 10−9 M to 1.0 × 10−7 M, respectively. The limits of detection (3σ are 1.0 × 10−11 M for TEB, and 1.3 × 10−11 for SAL respectively. Relative standard deviations (n = 11 are less than 2% for 5.0 × 10−8 M SAL and TEB. Possible reaction mechanisms for the CL system are suggested based on the CL system spectra, Ni(IV complex oxidation characteristics, and electron spin resonance (ESR techniques. The proposed method has been applied to the analysis of urine and swine feed samples with satisfactory results.

  13. Cyclopentadienyluranium(IV) acetylacetonates

    International Nuclear Information System (INIS)

    Bagnall, K.W.; Edwards, J.; Rickard, C.E.F.; Tempest, A.C.

    1979-01-01

    Cyclopentadienyluranium(IV) acetylacetonate complexes, (eta 5 C 5 H 5 )UClsub(3-x)(acac)sub(x), where x = 1 or 2, and the corresponding bis triphenylphosphine oxide (tppo) complexes have been prepared. The bis cyclopentadienyl complexes, (eta 5 C 5 H 5 ) 2 U(acac) 2 and (eta 5 C 5 H 5 ) 2 UCl(acac)(tppo) 2 have also been prepared and are stable with respect to disproportionation, whereas (eta 5 C 5 H 5 ) 2 UCl(acac) is not. The IR and UV/visible spectra of the complexes are reported, together with some additional information on the UCl 2 (acac) 2 thf and -tppo systems. (author)

  14. The G4-ECONS Economic Evaluation Tool for Generation IV Reactor Systems and its Proposed Application to Deliberately Small Reactor Systems and Proposed New Nuclear Fuel Cycle Facilities. Annex IX

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-12-15

    At the outset of the international Generation IV programme, it was decided that the six candidate reactor systems will ultimately be evaluated on the basis of safety, sustainability, non-proliferation attributes, technical readiness and projected economics. It is likely that the same factors will influence the evaluation of deliberately small reactor systems1 and new fuel cycle facilities, such as reprocessing plants that are being considered under the more recent Global Nuclear Energy Partnership (GNEP). This annex describes how the development of an economic modelling system has evolved to address the issue of economic competitiveness for both the Generation IV and GNEP programmes. In 2004, the Generation IV Economic Modelling Working Group (EMWG) commissioned the development of a Microsoft Excel based model capable of calculating the levelized unit electricity cost (LUEC) in mills/kW.h (1 mill = $10{sup -3}) or $/MW.h for multiple types of reactor system being developed under the Generation IV programme. This overall modelling system is now called the Generation IV spreadsheet calculation of nuclear systems (G4-ECONS), and is being expanded to calculate costs of energy products in addition to electricity, such as hydrogen and desalinated water. A version has also been developed to evaluate the costs of products or services from fuel cycle facilities. The cost estimating methodology and algorithms are explained in detail in the Generation IV Cost Estimating Guidelines and in the G4-ECONS User's Manual. The model was constructed with relatively simple economic algorithms such that it could be used by almost any nation without regard to country specific taxation, cost accounting, depreciation or capital cost recovery methodologies. It was also designed with transparency to the user in mind (i.e. all algorithms and cell contents are visible to the user). A short description of version 1.0 G4-ECONS-R (reactor economics model) has also been published in the

  15. The G4-ECONS Economic Evaluation Tool for Generation IV Reactor Systems and its Proposed Application to Deliberately Small Reactor Systems and Proposed New Nuclear Fuel Cycle Facilities. Annex IX

    International Nuclear Information System (INIS)

    2013-01-01

    At the outset of the international Generation IV programme, it was decided that the six candidate reactor systems will ultimately be evaluated on the basis of safety, sustainability, non-proliferation attributes, technical readiness and projected economics. It is likely that the same factors will influence the evaluation of deliberately small reactor systems1 and new fuel cycle facilities, such as reprocessing plants that are being considered under the more recent Global Nuclear Energy Partnership (GNEP). This annex describes how the development of an economic modelling system has evolved to address the issue of economic competitiveness for both the Generation IV and GNEP programmes. In 2004, the Generation IV Economic Modelling Working Group (EMWG) commissioned the development of a Microsoft Excel based model capable of calculating the levelized unit electricity cost (LUEC) in mills/kW.h (1 mill = $10 -3 ) or $/MW.h for multiple types of reactor system being developed under the Generation IV programme. This overall modelling system is now called the Generation IV spreadsheet calculation of nuclear systems (G4-ECONS), and is being expanded to calculate costs of energy products in addition to electricity, such as hydrogen and desalinated water. A version has also been developed to evaluate the costs of products or services from fuel cycle facilities. The cost estimating methodology and algorithms are explained in detail in the Generation IV Cost Estimating Guidelines and in the G4-ECONS User's Manual. The model was constructed with relatively simple economic algorithms such that it could be used by almost any nation without regard to country specific taxation, cost accounting, depreciation or capital cost recovery methodologies. It was also designed with transparency to the user in mind (i.e. all algorithms and cell contents are visible to the user). A short description of version 1.0 G4-ECONS-R (reactor economics model) has also been published in the Proceedings of

  16. Multisensor system for determination of iron(II), iron(III), uranium(VI) and uranium(IV) in complex solutions

    International Nuclear Information System (INIS)

    Legin, A.V.; Seleznev, B.L.; Rudnitskaya, A.M.; Vlasov, Yu.G.; Tverdokhlebov, S.V.; Mack, B.; Abraham, A.; Arnold, T.; Baraniak, L.; Nitsche, H.

    1999-01-01

    Development and analytical evaluation of a multisensor system based on the principles of 'electronic tongue' for the determination of low contents of uranium(VI), uranium(IV), iron(II) and iron(III) in complex aqueous media have been carried out. A set of 29 different chemical sensors on the basis of all- solid-state crystalline and vitreous materials with enhanced electronic conductivity and redox and ionic cross-sensitivity have been incorporated into the sensor array. Multidimensional data have been processed by pattern recognition methods such as artificial neural networks and partial least squares. It has been demonstrated that Fe(II) and Fe(III) contents in the range from 10 -7 to 10 -4 mol L -1 of total iron concentration can be determined with the average precision of about 25 %. U(VI) and U(IV) contents can been determined with the average precision of 10-40% depending on the concentration. The developed multisensor system can be applied in future for the analysis of mining and borehole waters as well other contaminated natural media, including on-site measurements. (author)

  17. Flow-injection chemiluminescence assay for ultra-trace determination of DNA using rhodamine B-Ce(IV)-DNA ternary system in sulfuric acid media

    International Nuclear Information System (INIS)

    Ma Yongjun; Zhou Min; Jin Xiaoyong; Zhang Ziyu; Teng Xiulan; Chen Hui

    2004-01-01

    A novel flow-injection chemiluminescence method for the determination of DNA at ultra-trace level has been established. In 0.8 M sulfuric acid media, the chemiluminescence of the rhodamine B-cerium (IV) or Ce(IV) system is enhanced by DNA, activated previously by imidazole-HCl buffer solution (pH 7.0). The enhanced intensity of chemiluminescence is in proportion to log DNA concentration 1.0x10 -8 to 0.1 μg ml -1 for herring sperm DNA and 2.0x10 -6 to 0.2 μg ml -1 for calf thymus DNA with 3σ detection limits of 8.3x10 -9 μg ml -1 for herring sperm DNA and 3.5x10 -7 μg ml -1 for calf thymus DNA, respectively. The relative standard deviation for 1.0x10 -4 μg ml -1 herring sperm DNA was 0.99% and 2.0x10 -3 μg ml -1 for calf thymus DNA was 1.1% (n=11). Using the optimized system, DNA contents in six synthetic samples has been determined with recoveries of 99.5-109.0%. The possible mechanism has also been studied in this paper

  18. Flow-injection chemiluminescence assay for ultra-trace determination of DNA using rhodamine B-Ce(IV)-DNA ternary system in sulfuric acid media

    Energy Technology Data Exchange (ETDEWEB)

    Ma Yongjun; Zhou Min; Jin Xiaoyong; Zhang Ziyu; Teng Xiulan; Chen Hui

    2004-01-09

    A novel flow-injection chemiluminescence method for the determination of DNA at ultra-trace level has been established. In 0.8 M sulfuric acid media, the chemiluminescence of the rhodamine B-cerium (IV) or Ce(IV) system is enhanced by DNA, activated previously by imidazole-HCl buffer solution (pH 7.0). The enhanced intensity of chemiluminescence is in proportion to log DNA concentration 1.0x10{sup -8} to 0.1 {mu}g ml{sup -1} for herring sperm DNA and 2.0x10{sup -6} to 0.2 {mu}g ml{sup -1} for calf thymus DNA with 3{sigma} detection limits of 8.3x10{sup -9} {mu}g ml{sup -1} for herring sperm DNA and 3.5x10{sup -7} {mu}g ml{sup -1} for calf thymus DNA, respectively. The relative standard deviation for 1.0x10{sup -4} {mu}g ml{sup -1} herring sperm DNA was 0.99% and 2.0x10{sup -3} {mu}g ml{sup -1} for calf thymus DNA was 1.1% (n=11). Using the optimized system, DNA contents in six synthetic samples has been determined with recoveries of 99.5-109.0%. The possible mechanism has also been studied in this paper.

  19. LoRad M IV with stereologic stereotactic system for breast screening and follow-up examinations

    International Nuclear Information System (INIS)

    1999-01-01

    The LoRad M IV mammography unit was assessed clinically by radiological staff at the West Suffolk Hospital Breast Screening Unit, Bury St Edmonds for screening and assessment, and at the South East Scotland Breast Screening Centre for screening only. A full technical assessment was made in September 1998 by Physics staff from KCARE at Bury St Edmonds. The unit was physically assessed as an assessment mammography unit. The physical checks indicated that the unit met the requirements of MDA/95/40 with the following notable exceptions: The x-ray tube current is less than 100 ma at 28 kV. The available range of mAs is less than the recommended levels. The 'preparation' delay is over 1 second. Exposures can be made with the cassette out of position. The magnification factor is less than 1.8 x. The lead equivalent should be marked on the protective screen. Some of these points of non compliance will have no relevance for some applications. It is necessary that prospective purchasers should be aware of them even though they are not reflected in adverse comment by the assessors

  20. Why Did Socrates Deny That He Was a Teacher? Locating Socrates among the New Educators and the Traditional Education in Plato's "Apology of Socrates"

    Science.gov (United States)

    Mintz, Avi I.

    2014-01-01

    Plato's "Apology of Socrates" contains a spirited account of Socrates' relationship with the city of Athens and its citizens. As Socrates stands on trial for corrupting the youth, surprisingly, he does not defend the substance and the methods of his teaching. Instead, he simply denies that he is a teacher. Many scholars have…

  1. The Case against the Arts from Plato to Tolstoy and Its Implications for Why and How the Arts Should Be Taught in Schools

    Science.gov (United States)

    Tate, Nicholas

    2016-01-01

    From Plato onwards many of the great Western thinkers have explored the nature of the arts, their contribution to society and their role in education. This has often involved a discussion of the potentially negative impact of the arts. The recurring message has been that the arts can warp judgment, elevate emotion at the expense of reason,…

  2. Oxygen Atom Transfer Using an Iron(IV)-Oxo Embedded in a Tetracyclic N-Heterocyclic Carbene System: How Does the Reactivity Compare to Cytochrome P450 Compound I?

    Science.gov (United States)

    Cantú Reinhard, Fabián G; de Visser, Sam P

    2017-02-24

    N-Heterocyclic carbenes (NHC) are commonly featured as ligands in transition metal catalysis. Recently, a cyclic system containing four NHC groups with a central iron atom was synthesized and its iron(IV)-oxo species, [Fe IV (O)(cNHC 4 )] 2+ , was characterized. This tetracyclic NHC ligand system may give the iron(IV)-oxo species unique catalytic properties as compared to traditional non-heme and heme iron ligand systems. Therefore, we performed a computational study on the structure and reactivity of the [Fe IV (O)(cNHC 4 )] 2+ complex in substrate hydroxylation and epoxidation reactions. The reactivity patterns are compared with cytochrome P450 Compound I and non-heme iron(IV)-oxo models and it is shown that the [Fe IV (O)(cNHC 4 )] 2+ system is an effective oxidant with oxidative power analogous to P450 Compound I. Unfortunately, in polar solvents, a solvent molecule will bind to the sixth ligand position and decrease the catalytic activity of the oxidant. A molecular orbital and valence bond analysis provides insight into the origin of the reactivity differences and makes predictions of how to further exploit these systems in chemical catalysis. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  3. A hipotética linguagem ideal de Platão Plato's hypothetical ideal language

    Directory of Open Access Journals (Sweden)

    Maria Carolina Alves dos Santos

    2003-01-01

    Full Text Available Para que um discurso sobre o espetáculo do mundo transcendente seja acolhido como totalidade inteligível e coerente, urge desvencilhar-se da arbitrariedade do domínio de trêmulos contornos do sensível, esfera de opiniões apenas. É o que propõe Platão, na esteira das reflexões dos primeiros pensadores: para suprir deficiências que causam a elisão da realidade e transformar a linguagem num veículo de intelecção autêntica dos conceitos essenciais de um pensar filosófico, ele a coloca no centro de uma especulação rigorosa. Tal como seus antecessores Heráclito e Parmênides, Platão revela logofilia ao empenhar-se na construção de uma nova estrutura discursiva, diferente daquela do homem comum, desencadeando no campo da Filosofia uma revolução que se tornara indispensável: elabora um modelo fundador - princípio de uma ordem permanente propedêutica à construção de uma linguagem formal e abstrata - referente a entes que os homens, na maioria, por si mesmos não conseguem visualizar. Somente nela poderá reverberar a verdade universal das Formas que, ao emprestarem seus nomes à infindável série dos particulares sensíveis, os clarifica e lhes confere significação. Com as teorias que a partir das Formas desenvolve e expõe nos Diálogos, o filósofo visa induzir o leitor a preparar-se para operar, metodicamente, a conversão de sua alma ao plano desses seres ideais, supra-sensíveis, e apreender, assim, a realidade que tudo fundamenta e torna cognoscível.For a discourse on the spectacle of the transcendental world to be received in its comprehensible and coherent totality, its needs to get rid of the arbitrariness of the dominion of tremulous shapes of the sensitive, which is merely the sphere of opinions. This is what Plato suggests, following the course of reflection of the first thinkers: in order to compensate the deficiencies that entail elision of reality and to transform language into a vehicle of authentic

  4. Clockwise rotation of the Santa Marta massif and simultaneous Paleogene to Neogene deformation of the Plato-San Jorge and Cesar-Ranchería basins

    Science.gov (United States)

    Montes, Camilo; Guzman, Georgina; Bayona, German; Cardona, Agustin; Valencia, Victor; Jaramillo, Carlos

    2010-10-01

    A moderate amount of vertical-axis clockwise rotation of the Santa Marta massif (30°) explains as much as 115 km of extension (stretching of 1.75) along its trailing edge (Plato-San Jorge basin) and up to 56 km of simultaneous shortening with an angular shear of 0.57 along its leading edge (Perijá range). Extensional deformation is recorded in the 260 km-wide, fan-shaped Plato-San Jorge basin by a 2-8 km thick, shallowing-upward and almost entirely fine-grained, upper Eocene and younger sedimentary sequence. The simultaneous initiation of shortening in the Cesar-Ranchería basin is documented by Mesozoic strata placed on to lower Eocene syntectonic strata (Tabaco Formation and equivalents) along the northwest-verging, shallow dipping (9-12° to the southeast) and discrete Cerrejón thrust. First-order subsidence analysis in the Plato-San Jorge basin is consistent with crustal stretching values between 1.5 and 2, also predicted by the rigid-body rotation of the Santa Marta massif. The model predicts about 100 km of right-lateral displacement along the Oca fault and 45 km of left-lateral displacement along the Santa Marta-Bucaramanga fault. Clockwise rotation of a rigid Santa Marta massif, and simultaneous Paleogene opening of the Plato-San Jorge basin and emplacement of the Cerrejón thrust sheet would have resulted in the fragmentation of the Cordillera Central-Santa Marta massif province. New U/Pb ages (241 ± 3 Ma) on granitoid rocks from industry boreholes in the Plato-San Jorge basin confirm the presence of fragments of a now segmented, Late Permian to Early Triassic age, two-mica, granitic province that once spanned the Santa Marta massif to the northernmost Cordillera Central.

  5. Fiber optic systems for mobile platforms IV; Proceedings of the Meeting, San Jose, CA, Sept. 18, 1990

    International Nuclear Information System (INIS)

    Lewis, N.E.; Moore, E.L.

    1991-01-01

    The present conference on fiber-optic (FO) systems discusses topics in shipboard, automotive, spacecraft, and aeronautical FO applications. Attention is given to an FO interferometric ellipsoidal shell hydrophone, an FO backbone for a submarine combat system, EM environmental effects on shipboard FO installations, and recent developments in polymeric FO systems for automotive use. Also discussed are a wavelength-multiplexed FO position encoder for aircraft control systems, a code-division multiple-access system for integrated modular avionics, fly-by-light systems for commercial aircraft, FO temperature sensors for aerospace applications, a hybrid FO/electrical network for launch vehicles, the effects of ionizing radiation on FO systems, and FO systems in liquid propellant rocket environments

  6. Fiber optic systems for mobile platforms IV; Proceedings of the Meeting, San Jose, CA, Sept. 18, 1990

    Science.gov (United States)

    Lewis, Norris E.; Moore, Emery L.

    The present conference on fiber-optic (FO) systems discusses topics in shipboard, automotive, spacecraft, and aeronautical FO applications. Attention is given to an FO interferometric ellipsoidal shell hydrophone, an FO backbone for a submarine combat system, EM environmental effects on shipboard FO installations, and recent developments in polymeric FO systems for automotive use. Also discussed are a wavelength-multiplexed FO position encoder for aircraft control systems, a code-division multiple-access system for integrated modular avionics, fly-by-light systems for commercial aircraft, FO temperature sensors for aerospace applications, a hybrid FO/electrical network for launch vehicles, the effects of ionizing radiation on FO systems, and FO systems in liquid propellant rocket environments.

  7. Fiber optic systems for mobile platforms IV; Proceedings of the Meeting, San Jose, CA, Sept. 18, 1990

    Energy Technology Data Exchange (ETDEWEB)

    Lewis, N.E.; Moore, E.L.

    1991-01-01

    The present conference on fiber-optic (FO) systems discusses topics in shipboard, automotive, spacecraft, and aeronautical FO applications. Attention is given to an FO interferometric ellipsoidal shell hydrophone, an FO backbone for a submarine combat system, EM environmental effects on shipboard FO installations, and recent developments in polymeric FO systems for automotive use. Also discussed are a wavelength-multiplexed FO position encoder for aircraft control systems, a code-division multiple-access system for integrated modular avionics, fly-by-light systems for commercial aircraft, FO temperature sensors for aerospace applications, a hybrid FO/electrical network for launch vehicles, the effects of ionizing radiation on FO systems, and FO systems in liquid propellant rocket environments.

  8. Nuclear proliferation and civilian nuclear power. Report of the Nonproliferation Alternative Systems Assessment Program. Volume IV. Commercial potential

    Energy Technology Data Exchange (ETDEWEB)

    1980-06-01

    This volume of the Nonproliferation Alternative Systems Assessment Program (NASAP) report provides time and cost estimates for positioning new nuclear power systems for commercial deployment. The assessment also estimates the rates at which the new systems might penetrate the domestic market, assuming the continuing viability of the massive light-water reactor network that now exists worldwide. This assessment does not recommend specific, detailed program plans and budgets for individual systems; however, it is clear from this analysis that any of the systems investigated could be deployed if dictated by national interest.

  9. Nuclear proliferation and civilian nuclear power. Report of the Nonproliferation Alternative Systems Assessment Program. Volume IV. Commercial potential

    International Nuclear Information System (INIS)

    1980-06-01

    This volume of the Nonproliferation Alternative Systems Assessment Program (NASAP) report provides time and cost estimates for positioning new nuclear power systems for commercial deployment. The assessment also estimates the rates at which the new systems might penetrate the domestic market, assuming the continuing viability of the massive light-water reactor network that now exists worldwide. This assessment does not recommend specific, detailed program plans and budgets for individual systems; however, it is clear from this analysis that any of the systems investigated could be deployed if dictated by national interest

  10. A theranostic prodrug delivery system based on Pt(IV) conjugated nano-graphene oxide with synergistic effect to enhance the therapeutic efficacy of Pt drug.

    Science.gov (United States)

    Li, Jingwen; Lyv, Zhonglin; Li, Yanli; Liu, Huan; Wang, Jinkui; Zhan, Wenjun; Chen, Hong; Chen, Huabing; Li, Xinming

    2015-05-01

    Due to their high NIR-optical absorption and high specific surface area, graphene oxide and graphene oxide-based nanocomposites have great potential in both drug delivery and photothermal therapy. In the work reported herein we successfully integrate a Pt(IV) complex (c,c,t-[Pt(NH3)2Cl2(OH)2]), PEGylated nano-graphene oxide (PEG-NGO), and a cell apoptosis sensor into a single platform to generate a multifunctional nanocomposite (PEG-NGO-Pt) which shows potential for targeted drug delivery and combined photothermal-chemotherapy under near infrared laser irradiation (NIR), and real-time monitoring of its therapeutic efficacy. Non-invasive imaging using a fluorescent probe immobilized on the GO shows an enhanced therapeutic effect of PEG-NGO-Pt in cancer treatment via apoptosis and cell death. Due to the enhanced cytotoxicity of cisplatin and the highly specific tumor targeting of PEG-NGO-Pt at elevated temperatures, this nanocomposite displays a synergistic effect in improving the therapeutic efficacy of the Pt drug with complete destruction of tumors, no tumor recurrence and minimal systemic toxicity in comparison with chemotherapy or photothermal treatment alone, highlighting the advantageous effects of integrating Pt(IV) with GO for anticancer treatment. Copyright © 2015 Elsevier Ltd. All rights reserved.

  11. Polymerization of acrylamide initiated with Ce(IV- and KMnO4–mercaptosuccinic acid redox systems in acid-aqueous medium

    Directory of Open Access Journals (Sweden)

    2007-03-01

    Full Text Available By using mercaptosuccinic acid-cerium(IV sulfate and mercaptosuccinic acid-KMnO4 redox systems in acid aqueous medium, the polymerization of acrylamide monomer was performed at room temperatures. Water soluble acrylamide polymers which contain mercaptosuccinic acid end-groups were synthesized. The dependence of polymerization yield and the molecular weight of polymer on the initiator concentration(nMSA=nCe(IV at different acid concentrations, polymerization time, temperature, and concentration of sulfuric acid was investigated. The decrease in the initiator concentration resulted in an increase in the molecular weights but a decrease in the yield. The increase of reaction temperature from 20 to 60°C resulted in an increase in the molecular weights and slight decrease of the yield of polymer. Cerium and manganese ions are reduced to Ce(III and Mn(II ions respectively in polymerization reaction. The existence of Ce(III ion bound to polymer was investigated by UV-visible spectrometry and fluorescence measurements. The amount of Mn(II which is incorporated to the polymer was determined.

  12. Polypropylene non-woven fabric membrane via surface modification with biomimetic phosphorylcholine in Ce(IV)/HNO{sub 3} redox system

    Energy Technology Data Exchange (ETDEWEB)

    Zhao Jie; Shi Qiang; Luan Shifang; Song Lingjie; Yang Huawei [State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022 (China); Stagnaro, Paola [Istituto per Io Studio delle Macromolecole, Consiglio Nazionale delle Ricerche, Via de Marini 6, 16149 Genova (Italy); Yin Jinghua, E-mail: yinjh@ciac.jl.cn [State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022 (China)

    2012-10-01

    Surface modification of polypropylene non-woven fabric membrane (NWF) for improving its hemocompatibility was developed by grafting a biomimic monomer, 2-methacryloyloxyethyl phosphorycholine (MPC). The NWF membrane surface was first activated by potassium peroxydisulfate to form hydroxyl groups, and then grafted with MPC using ceric (IV) ammonium nitrate as the redox initiator. The surface chemical changes before and after modification were confirmed by Fourier transform infrared spectroscopy with an ATR unit (FTIR-ATR) and X-ray photoelectron spectroscopy (XPS); the water contact angle results showed the gradual changes in wettability from hydrophobic to hydrophilic surface. Meanwhile, the hemocompatibility of these samples was also evaluated by protein adsorption and platelet adhesion. These experimental results exhibited that the introduction of poly(MPC) onto the NWF membrane surfaces substantially improved their hemocompatibility. The feasibility and simplicity of this procedure may lead to potential applications of NWF membranes in biomedical separation and blood purification. - Graphical abstract: 2-methacryloyloxyethyl phosphorycholine (MPC), was grafted onto non-woven fabric (NWF) membrane surface by Ce(IV)/HNO{sub 3} redox system. The protein adsorption and platelet adhesion were substantially suppressed by the introduction of poly(MPC). Highlights: Black-Right-Pointing-Pointer MPC was successfully grafted onto NWF PP membrane surface. Black-Right-Pointing-Pointer Obviously enhanced hemocompatibility was acquired by the modified samples. Black-Right-Pointing-Pointer A facile redox grafting was adopted in the whole process.

  13. Protecting the pipeline of science: openness, scientific methods and the lessons from ticagrelor and the PLATO trial.

    Science.gov (United States)

    Coats, Andrew J Stewart; Nijjer, Sukhjinder S; Francis, Darrel P

    2014-10-20

    Ticagrelor, a potent antiplatelet, has been shown to be beneficial in patients with acute coronary syndromes in a randomised controlled trial published in a highly ranked peer reviewed journal. Accordingly it has entered guidelines and has been approved for clinical use by authorities. However, there remains a controversy regarding aspects of the PLATO trial, which are not immediately apparent from the peer-reviewed publications. A number of publications have sought to highlight potential discrepancies, using data available in publicly published documents from the US Food and Drug Administration (FDA) leading to disagreement regarding the value of open science and data sharing. We reflect upon potential sources of bias present in even rigorously performed randomised controlled trials, on whether peer review can establish the presence of bias and the need to constantly challenge and question even accepted data. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  14. Infância e educação em Platão Childhood and education in Plato

    Directory of Open Access Journals (Sweden)

    Walter Omar Kohan

    2003-06-01

    Full Text Available Este trabalho estuda, desde uma perspectiva filosófica, o conceito de infância em Platão, com ênfase nos seguintes diálogos: Alcibíades I, Górgias, A República e As Leis. Num primeiro momento, situamos a questão da infância no marco mais ampliado do projeto filosófico e político de Platão. A seguir, propomos quatro traços principais do conceito de infância em Platão: a como possibilidade (as crianças podem ser qualquer coisa no futuro; b como inferioridade (as crianças - como as mulheres, estrangeiros e escravos - são inferiores em relação ao homem adulto cidadão; c como superfluidade (a infância não é necessária à pólis; d como material da política (a utopia se constrói a partir da educação das crianças. Não há a pretensão de levar Platão a algum tribunal. Busca-se apenas delimitar um problema e uma forma específica de enfrentá-lo, com vistas a contribuir para a análise da produtividade dessa perspectiva na história da filosofia da infância e da educação ocidental, bem como nas atuais teorias e práticas educacionais. Ao mesmo tempo, de forma implícita, procura-se oferecer elementos para problematizar uma visão já consolidada entre os historiadores da infância - particularmente desde o já clássico História social da infância e da família de Philippe Ariès -, segundo a qual a infância seria uma invenção moderna e ela não teria sido "pensada" pelos antigos enquanto tal.This work investigates from a philosophical perspective the concept of childhood in Plato, with an emphasis on the following dialogues: Alcibiades I, Gorgias, The Republic, and The Laws. Initially, we situate the issue of childhood within the wider scenario of Plato's political and philosophical project. We then propose four main features of the concept of childhood in Plato: a as possibility (children can become anything in future; b as inferiority (children - like women, foreigners and slaves - are inferior to the male

  15. Generation IV national program

    International Nuclear Information System (INIS)

    Preville, M.; Sadhankar, R.; Brady, D.

    2007-01-01

    This paper outlines the Generation IV National Program. This program involves evolutionary and innovative design with significantly higher efficiencies (∼50% compared to present ∼30%) - sustainable, economical, safe, reliable and proliferation resistant - for future energy security. The Generation IV Forum (GIF) effectively leverages the resources of the participants to meet these goals. Ten countries signed the GIF Charter in 2001

  16. Current state of knowledge of hepatic encephalopathy (part IV): Management of Hepatic Encephalopathy by liver support systems.

    Science.gov (United States)

    Hassanein, Tarek

    2017-04-01

    Hepatic Encephalopathy is a devastating complication of End-Stage Liver Disease. In its severe grades it requires extra intervention beyond the standard medical approaches. In this article were view the role of liver support systems in managing hepatic encephalopthy.

  17. Physics of laser fusion. Volume IV. The future development of high-power solid-state laser systems

    International Nuclear Information System (INIS)

    Emmett, J.L.; Krupke, W.F.; Trenholme, J.B.

    1982-11-01

    Solid state lasers, particularly neodymium glass systems, have undergone intensive development during the last decade. In this paper, we review solid state laser technology in the context of high-peak-power systems for inertial confinement fusion. Specifically addressed are five major factors: efficiency, wavelength flexibility, average power, system complexity, and cost; these factors today limit broader application of the technology. We conclude that each of these factors can be greatly improved within current fundamental physical limits. We further conclude that the systematic development of new solid state laser madia, both vitreous and crystalline, should ultimately permit the development of wavelength-flexible, very high average power systems with overall efficiencies in the range of 10 to 20%

  18. Elmo Bumpy Torus proof of principle, Phase II: Title 1 report. Volume IV. Microwave system. Preliminary design report

    International Nuclear Information System (INIS)

    Adams, R.N.

    1982-01-01

    The EBT-P Microwave System provides microwaves for electron cyclotron resonance heating (ECRH) to both stabilize and heat the EBT-P plasma. A 28 gigahertz (GHz) system is required to form the hot electron annulus plasma that provides MHD stabilization to the core plasma. A 60 GHz system is required to heat the core plasma and will provide some second harmonic heating of the hot electron annulus. The principal microwave system elements and their design characteristics are summarized. The microwave system includes 200 kilowatt (kW) gyrotrons at 60 GHz for core heating and 200 kW gyrotrons at 28 GHz for annulus heating. The basic operating complement will be six (6) 60 GHz tubes and two (2) 28 GHz tubes. PACE (Plant and Capital Equipment) procurement will include four (4) 60 GHz gyrotrons with two (2) GHz tubes procured under operations and the two (2) 28 GHz tubes will be provided, with mounts, from the EBT-S program. Each tube is rigidly mounted on an oil filled tank assembly which provides electrical isolation and cooling. All tubes and mounts will be located in the lower level of the torus enclosure. An extensive demineralized water flow system is required to provide gyrotron cooling

  19. Meta-Analysis of the Ease of Care From the Nurses' Perspective Comparing Fentanyl Iontophoretic Transdermal System (ITS) Vs Morphine Intravenous Patient-Controlled Analgesia (IV PCA) in Postoperative Pain Management.

    Science.gov (United States)

    Pestano, Cecile R; Lindley, Pam; Ding, Li; Danesi, Hassan; Jones, James B

    2017-08-01

    The aim of this meta-analysis was to compare the ease of care (EOC) of fentanyl iontophoretic transdermal system (ITS) vs the morphine intravenous patient-controlled analgesia (IV PCA) as assessed by the nurse. Meta-analysis of three phase 3B randomized active-comparator trials. This meta-analysis according to Cochrane's approach assessed EOC using a validated nurse questionnaire (22 items grouped into three subscales, which include time efficiency, convenience, and satisfaction) in adult patients treated with fentanyl ITS or morphine IV PCA for postoperative pain management. The weighted mean difference (WMD) between treatments was calculated. EOC analyses were based on responses to questionnaires from 848 (fentanyl ITS) and 761 (morphine IV PCA) nurses. Fentanyl ITS was reported to provide significant advantages compared with morphine IV PCA in terms of nurses' overall EOC (WMD = -0.57, P PCA. Copyright © 2016 American Society of PeriAnesthesia Nurses. Published by Elsevier Inc. All rights reserved.

  20. TRANSIT TIMING OBSERVATIONS FROM KEPLER. IV. CONFIRMATION OF FOUR MULTIPLE-PLANET SYSTEMS BY SIMPLE PHYSICAL MODELS

    International Nuclear Information System (INIS)

    Fabrycky, Daniel C.; Ford, Eric B.; Moorhead, Althea V.; Steffen, Jason H.; Rowe, Jason F.; Christiansen, Jessie L.; Carter, Joshua A.; Fressin, Francois; Geary, John; Batalha, Natalie M.; Borucki, William J.; Bryson, Steve; Haas, Michael R.; Buchhave, Lars A.; Ciardi, David R.; Cochran, William D.; Endl, Michael; Fanelli, Michael N.; Fischer, Debra; Hall, Jennifer R.

    2012-01-01

    Eighty planetary systems of two or more planets are known to orbit stars other than the Sun. For most, the data can be sufficiently explained by non-interacting Keplerian orbits, so the dynamical interactions of these systems have not been observed. Here we present four sets of light curves from the Kepler spacecraft, each which of shows multiple planets transiting the same star. Departure of the timing of these transits from strict periodicity indicates that the planets are perturbing each other: the observed timing variations match the forcing frequency of the other planet. This confirms that these objects are in the same system. Next we limit their masses to the planetary regime by requiring the system remain stable for astronomical timescales. Finally, we report dynamical fits to the transit times, yielding possible values for the planets' masses and eccentricities. As the timespan of timing data increases, dynamical fits may allow detailed constraints on the systems' architectures, even in cases for which high-precision Doppler follow-up is impractical.

  1. TRANSIT TIMING OBSERVATIONS FROM KEPLER. IV. CONFIRMATION OF FOUR MULTIPLE-PLANET SYSTEMS BY SIMPLE PHYSICAL MODELS

    Energy Technology Data Exchange (ETDEWEB)

    Fabrycky, Daniel C. [Department of Astronomy and Astrophysics, University of California, Santa Cruz, Santa Cruz, CA 95064 (United States); Ford, Eric B.; Moorhead, Althea V. [Astronomy Department, University of Florida, 211 Bryant Space Sciences Center, Gainesville, FL 32111 (United States); Steffen, Jason H. [Fermilab Center for Particle Astrophysics, P.O. Box 500, MS 127, Batavia, IL 60510 (United States); Rowe, Jason F.; Christiansen, Jessie L. [SETI Institute, Mountain View, CA 94043 (United States); Carter, Joshua A.; Fressin, Francois; Geary, John [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Batalha, Natalie M. [Department of Physics and Astronomy, San Jose State University, San Jose, CA 95192 (United States); Borucki, William J.; Bryson, Steve; Haas, Michael R. [NASA Ames Research Center, Moffett Field, CA, 94035 (United States); Buchhave, Lars A. [Department of Astrophysics and Planetary Science, Niels Bohr Institute, University of Copenhagen, DK-2100 Copenhagen (Denmark); Ciardi, David R. [NASA Exoplanet Science Institute/Caltech, Pasadena, CA 91126 (United States); Cochran, William D.; Endl, Michael [McDonald Observatory, The University of Texas, Austin TX 78730 (United States); Fanelli, Michael N. [Bay Area Environmental Research Institute/NASA Ames Research Center, Moffett Field, CA 94035 (United States); Fischer, Debra [Astronomy Department, Yale University, New Haven, CT (United States); Hall, Jennifer R., E-mail: daniel.fabrycky@gmail.com [Orbital Sciences Corporation/NASA Ames Research Center, Moffett Field, CA 94035 (United States); and others

    2012-05-10

    Eighty planetary systems of two or more planets are known to orbit stars other than the Sun. For most, the data can be sufficiently explained by non-interacting Keplerian orbits, so the dynamical interactions of these systems have not been observed. Here we present four sets of light curves from the Kepler spacecraft, each which of shows multiple planets transiting the same star. Departure of the timing of these transits from strict periodicity indicates that the planets are perturbing each other: the observed timing variations match the forcing frequency of the other planet. This confirms that these objects are in the same system. Next we limit their masses to the planetary regime by requiring the system remain stable for astronomical timescales. Finally, we report dynamical fits to the transit times, yielding possible values for the planets' masses and eccentricities. As the timespan of timing data increases, dynamical fits may allow detailed constraints on the systems' architectures, even in cases for which high-precision Doppler follow-up is impractical.

  2. Neptunium (IV) oxalate solubility

    International Nuclear Information System (INIS)

    Luerkens, D.W.

    1983-07-01

    The equilibrium solubility of neptunium (IV) oxalate in nitric/oxalic acid solutions was determined at 22 0 C, 45 0 C, and 60 0 C. The concentrations of nitric/oxalic acid solutions represented a wide range of free oxalate ion concentration. A mathematical solubility model was developed which is based on the formation of the known complexes of neptunium (IV) oxalate. the solubility model uses a simplified concentration parameter which is proportional to the free oxalate ion concentration. The solubility model can be used to estimate the equilibrium solubility of neptunium (IV) oxalate over a wide range of oxalic and nitric acid concentrations at each temperature

  3. Materials for generation-IV nuclear reactors

    International Nuclear Information System (INIS)

    Alvarez, M. G.

    2009-01-01

    Materials science and materials development are key issues for the implementation of innovative reactor systems such as those defined in the framework of the Generation IV. Six systems have been selected for Generation IV consideration: gas-cooled fast reactor, lead-cooled fast reactor, molten salt-cooled reactor, sodium-cooled fast reactor, supercritical water-cooled reactor, and very high temperature reactor. The structural materials need to resist much higher temperatures, higher neutron doses and extremely corrosive environment, which are beyond the experience of the current nuclear power plants. For this reason, the first consideration in the development of Generation-IV concepts is selection and deployment of materials that operate successfully in the aggressive operating environments expected in the Gen-IV concepts. This paper summarizes the Gen-IV operating environments and describes the various candidate materials under consideration for use in different structural applications. (author)

  4. MTA Computer Based Evaluation System.

    Science.gov (United States)

    Brenner, Lisa P.; And Others

    The MTA PLATO-based evaluation system, which has been implemented by a consortium of schools of medical technology, is designed to be general-purpose, modular, data-driven, and interactive, and to accommodate other national and local item banks. The system provides a comprehensive interactive item-banking system in conjunction with online student…

  5. Investigation of a Novel NDE Method for Monitoring Thermomechanical Damage and Microstructure Evolution in Ferritic-Martensitic Steels for Generation IV Nuclear Energy Systems

    Energy Technology Data Exchange (ETDEWEB)

    Nagy, Peter

    2013-09-30

    materials. Through the results obtained from this integrated materials behavior and NDE study, new insight will be gained into the best nondestructive creep and microstructure monitoring methods for the particular mechanisms identified in these materials. The proposed project includes collaboration with a national laboratory partner and the results will also serve as a foundation to guide the efforts of scientists in the DOE laboratory, university, and industrial communities concerned with the technological challenges of monitoring creep and microstructural evolution in materials planned to be used in Generation IV Nuclear Energy Systems.

  6. Methanol production from eucalyptus wood chips. Attachment IV. Health and safety aspects of the eucalypt biomass to methanol energy system

    Energy Technology Data Exchange (ETDEWEB)

    Fishkind, H.H.

    1982-06-01

    The basic eucalyptus-to-methanol energy process is described and possible health and safety risks are identified at all steps of the process. The toxicology and treatment for exposure to these substances are described and mitigating measures are proposed. The health and safety impacts and risks of the wood gasification/methanol synthesis system are compared to those of the coal liquefaction and conversion system. The scope of this report includes the health and safety risks of workers (1) in the laboratory and greenhouse, where eucalyptus seedlings are developed, (2) at the biomass plantation, where these seedlings are planted and mature trees harvested, (3) transporting these logs and chips to the refinery, (4) in the hammermill, where the logs and chips will be reduced to small particles, (5) in the methanol synthesis plant, where the wood particles will be converted to methanol, and (6) transporting and dispensing the methanol. Finally, the health and safety risks of consumers using methanol is discussed.

  7. NNDSS - Table IV. Tuberculosis

    Data.gov (United States)

    U.S. Department of Health & Human Services — NNDSS - Table IV. Tuberculosis - 2016.This Table includes total number of cases reported in the United States, by region and by states, in accordance with the...

  8. NNDSS - Table IV. Tuberculosis

    Data.gov (United States)

    U.S. Department of Health & Human Services — NNDSS - Table IV. Tuberculosis - 2014.This Table includes total number of cases reported in the United States, by region and by states, in accordance with the...

  9. NNDSS - Table IV. Tuberculosis

    Data.gov (United States)

    U.S. Department of Health & Human Services — NNDSS - Table IV. Tuberculosis - 2015.This Table includes total number of cases reported in the United States, by region and by states, in accordance with the...

  10. SAGE IV Pathfinder

    Data.gov (United States)

    National Aeronautics and Space Administration — Utilizing a unique, new occultation technique involving imaging, the SAGE IV concept will meet or exceed the quality of previous SAGE measurements at a small...

  11. Postreplication Roles of the Brucella VirB Type IV Secretion System Uncovered via Conditional Expression of the VirB11 ATPase

    Directory of Open Access Journals (Sweden)

    Erin P. Smith

    2016-11-01

    Full Text Available Brucella abortus, the bacterial agent of the worldwide zoonosis brucellosis, primarily infects host phagocytes, where it undergoes an intracellular cycle within a dedicated membrane-bound vacuole, the Brucella-containing vacuole (BCV. Initially of endosomal origin (eBCV, BCVs are remodeled into replication-permissive organelles (rBCV derived from the host endoplasmic reticulum, a process that requires modulation of host secretory functions via delivery of effector proteins by the Brucella VirB type IV secretion system (T4SS. Following replication, rBCVs are converted into autophagic vacuoles (aBCVs that facilitate bacterial egress and subsequent infections, arguing that the bacterium sequentially manipulates multiple cellular pathways to complete its cycle. The VirB T4SS is essential for rBCV biogenesis, as VirB-deficient mutants are stalled in eBCVs and cannot mediate rBCV biogenesis. This has precluded analysis of whether the VirB apparatus also drives subsequent stages of the Brucella intracellular cycle. To address this issue, we have generated a B. abortus strain in which VirB T4SS function is conditionally controlled via anhydrotetracycline (ATc-dependent complementation of a deletion of the virB11 gene encoding the VirB11 ATPase. We show in murine bone marrow-derived macrophages (BMMs that early VirB production is essential for optimal rBCV biogenesis and bacterial replication. Transient expression of virB11 prior to infection was sufficient to mediate normal rBCV biogenesis and bacterial replication but led to T4SS inactivation and decreased aBCV formation and bacterial release, indicating that these postreplication stages are also T4SS dependent. Hence, our findings support the hypothesis of additional, postreplication roles of type IV secretion in the Brucella intracellular cycle.

  12. Transport systems of Ventricaria ventricosa: I/V analysis of both membranes in series as a function of [K(+)](o).

    Science.gov (United States)

    Beilby, M J; Bisson, M A

    1999-09-01

    The current-voltage (I/V) profiles of Ventricaria (formerly Valonia) membranes were measured at a range of external potassium concentrations, [K(+)](o), from 0.1 to 100 mm. The conductance-voltage (G/V) characteristics were computed to facilitate better resolution of the profile change with time after exposure to different [K(+)](o). The resistance-voltage (R/V) characteristics were computed to attempt resolution of plasmalemma and tonoplast. Four basic electrophysiological stages emerged: (1) Uniform low resistance between -60 and +60 mV after the cell impalement. (2) High resistance between +50 and +150 for [K(+)](o) from 0.1 to 1.0 mm and hypotonic media. (3) High resistance between -150 and -20 mV for [K(+)](o) of 10 mm (close to natural seawater) and hypertonic media. (4) High resistance between -150 and +170 mV at [K(+)](o) of 100 mm. The changes between these states were slow, requiring minutes to hours and sometimes exhibiting spontaneous oscillations of the membrane p.d. (potential difference). Our analysis of the I/V data supports a previous hypothesis, that Ventricaria tonoplast is the more resistive membrane containing a pump, which transports K(+) into the vacuole to regulate turgor. We associate state (1) with the plasmalemma conductance being dominant and the K(+) pump at the tonoplast short-circuited probably by a K(+) channel, state (2) with the K(+) pump "off" or short-circuited at p.d.s more negative than +50 mV, state (3) with the K(+) pump "on, " and state (4) with the pump dominant, but affected by high K(+). A model for the Ventricaria membrane system is proposed.

  13. Evaluating the environmental consequences of groundwater contamination. IV. Obtaining and utilizing contaminant arrival distributions in transient flow systems

    International Nuclear Information System (INIS)

    Nelson, R.W.

    1978-01-01

    The versatility of the new contaminant arrival distributions for determining environmental consequences of subsurface pollution problems is demonstrated through application to a transient flow system. Though some of the four phases of the hydrologic evaluations are more complicated because of the time dependence of the flow and input contaminant concentrations, the arrival distributions still effectively summarize the data required to determine the environmental implications. These arrival distributions yield two graphs or tabular sets of data giving the consequences of the subsurface pollution problems in a simple and direct form. 4 refs

  14. Green technology into nuclear industry Eligibility of Ambidexter nuclear complex for a generation IV nuclear power system

    International Nuclear Information System (INIS)

    Park, Kwangheon; Koh, Moosung; Ryu, Jeongdong; Kim, Yangeun; Lee, Bumsik; Park, Hyuntack

    2000-01-01

    Green power is being developed up to a point that is feasible not only in an environmental sense, but also in an economical viewpoint. This paper introduces two case studies that applied green technology into nuclear industry. 1) Nuclear laundry: A laundry machine that uses liquid and supercritical Co 2 as a solvent for decontamination of contaminated working dresses in nuclear power plants was developed. The machine consists of a 16 liter reactor, a recovery system with compressors, and storage tanks. All CO 2 used in cleaning is fully recovered and reused in next cleaning, resulting in no production

  15. Plan for IER-443 Testing of the Y-12 and AWE Criticality Accident Alarm System Detectors at the Godiva IV Burst Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Scorby, J. C. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Hickman, D. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Hudson, B. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Garbett, S. [Atomic Weapons Establishment (AWE), Berkshire (United Kingdom); Auld, G. [Atomic Weapons Establishment (AWE), Berkshire (United Kingdom); Horrne, A. [Atomic Weapons Establishment (AWE), Berkshire (United Kingdom); Beller, T. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Goda, J. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Haught, C. [Y-12 National Security Complex, Oak Ridge, TN (United States); Woodrow, C. [Y-12 National Security Complex, Oak Ridge, TN (United States); Ward, D. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-07-24

    This document provides the scope and details of the “Plan for Testing the Y-12 and AWE Criticality Accident Alarm System Detectors at the Godiva IV Burst Reactor”. Due to the relative simplicity of the testing goals, scope, and methodology, the NCSP Manager approved execution of the test when ready. No preliminary CED-1 or final design CED-2 reports were required or issued. The test will subject Criticality Accident Alarm System (CAAS) detectors supplied by Y- 12 and AWE to very intense and short duration mixed neutron and gamma radiation fields. The goals of the test will be to (1) substantiate functionality, for both existing and newly acquired Y- 12 CAAS detectors, and (2) the ability of the AWE detectors to provide quality temporal dose information after a hypothetical criticality accident. ANSI/ANS-8.3.1997 states that the “system shall be sufficiently robust as to actuate an alarm signal when exposed to the maximum radiation expected”, which has been defined at Y-12, in Documented Safety Analyses (DSAs), to be a dose rate of 10 Rad/s. ANSI/ANS-8.3.1997 further states that “alarm actuation shall occur as a result of a minimum duration transient” which may be assumed to be 1 msec. The pulse widths and dose rates which will be achieved in this test will exceed these requirements. Pulsed radiation fields will be produced by the Godiva IV fast metal burst reactor at the National Criticality Experimental Research Center (NCERC) at the Nevada National Security Site (NNSS). The magnitude of the pulses and the relative distances to the detectors will be varied to afford a wide range of radiation fluence and pulse widths. The magnitude of the neutron and gamma fields will be determined by reactor temperature rise to fluence and dose conversions which have been previously established through extensive measurements performed under IER-147. The requirements for CAAS systems to detect and alarm under a “minimum accident of concern” as well as other

  16. Multi-objective technico-economic optimization of energy conversion systems: hydrogen and electricity cogeneration from Generation IV nuclear reactor

    International Nuclear Information System (INIS)

    Gomez, A.

    2008-01-01

    With the increase in environmental considerations, such as the control of greenhouse emissions, and with the decrease in the fossil energy resources, hydrogen is currently considered as a promising energy vector. One of the main technological challenges of a future hydrogen economy is its large scale production without fossil fuel emissions. Under this context, nuclear energy is particularly adapted for hydrogen massive production by thermochemical cycles or high temperature electrolysis. One of the selected nuclear systems is the Very High Temperature Reactor (950 C/1200 C), cooled with helium, and dedicated to hydrogen production or to hydrogen electricity cogeneration. The main objective of this investigation, within the framework of a collaboration between CEA, French Atomic Agency (Cadarache) and LGC (Toulouse), consists in defining a technico-economic optimization methodology of electricity-hydrogen cogeneration systems, in order to identify and propose promising development strategies. Among the massive production processes of hydrogen, the thermochemical cycle Iodine-Sulphur has been considered. Taking into account the diversity of the used energies (i.e., heat and electricity) on the one hand and of the produced energies (hydrogen and electricity) on the other hand of the studied cogeneration system, an exergetic approach has been developed due to its ability to consider various energy forms on the same thermodynamical basis. The CYCLOP software tool (CEA) is used for the thermodynamic modelling of these systems. The economic criterion, calculated using the SEMER software tool (CEA), is based on the minimization of the total production site cost over its lifespan i.e., investment, operating costs and nuclear fuel cost. Capital investment involves the development of cost functions adapted to specific technologies and their specific operating conditions. The resulting optimization problems consist in maximizing the energy production, while minimizing the

  17. Austria; 2013 Article IV Consultation

    OpenAIRE

    International Monetary Fund

    2013-01-01

    This paper presents details of Austria’s 2013 Article IV Consultation. Austria has been growing economically but is facing challenges in the financial sector. Full implementation of medium-term fiscal adjustment plans require specifying several measures and plans that need gradual strengthening to take expected further bank restructuring cost into account. It suggests that strong early bank intervention and resolution tools, a better designed deposit insurance system, and a bank-financed reso...

  18. Evidence of the presence of a functional Dot/Icm type IV-B secretion system in the fish bacterial pathogen Piscirickettsia salmonis.

    Directory of Open Access Journals (Sweden)

    Fernando A Gómez

    Full Text Available Piscirickettsia salmonis is a fish bacterial pathogen that has severely challenged the sustainability of the Chilean salmon industry since its appearance in 1989. As this Gram-negative bacterium has been poorly characterized, relevant aspects of its life cycle, virulence and pathogenesis must be identified in order to properly design prophylactic procedures. This report provides evidence of the functional presence in P. salmonis of four genes homologous to those described for Dot/Icm Type IV Secretion Systems. The Dot/Icm System, the major virulence mechanism of phylogenetically related pathogens Legionella pneumophila and Coxiella burnetii, is responsible for their intracellular survival and multiplication, conditions that may also apply to P. salmonis. Our results demonstrate that the four P. salmonis dot/icm homologues (dotB, dotA, icmK and icmE are expressed both during in vitro tissue culture cells infection and growing in cell-free media, suggestive of their putative constitutive expression. Additionally, as it happens in other referential bacterial systems, temporal acidification of cell-free media results in over expression of all four P. salmonis genes, a well-known strategy by which SSTIV-containing bacteria inhibit phagosome-lysosome fusion to survive. These findings are very important to understand the virulence mechanisms of P. salmonis in order to design new prophylactic alternatives to control the disease.

  19. GASCON and MHDGAS: FORTRAN IV computer codes for calculating gas and condensed-phase compositions in the coal-fired open-cycle MHD system

    Energy Technology Data Exchange (ETDEWEB)

    Blackburn, P E

    1977-12-01

    Fortran IV computer codes have been written to calculate the equilibrium partial pressures of the gaseous phase and the quantity and composition of the condensed phases in the open-cycle MHD system. The codes are based on temperature-dependent equilibrium constants, mass conservation, the mass action law, and assumed ideal solution of compounds in each of two condensed phases. It is assumed that the phases are an oxide-silicate phase and a sulfate-carbonate-hydroxide phase. Calculations are iterated for gas and condensate concentrations while increasing or decreasing the total moles of elements, but keeping mole ratios constant, to achieve the desired total pressure. During iteration the oxygen partial pressure is incrementally changed. The decision to increase or decrease the oxygen pressure in this process depends on comparison of the oxygen content calculated in the gas and condensate phases with the initial amount of oxygen in the ash, coal, seed, and air. This process, together with a normalization step, allows the elements to converge to their initial quantities. Two versions of the computer code have been written. GASCON calculates the equilibrium gas partial pressures and the quantity and composition of the condensed phases in steps of thirteen temperature and pressure combinations in which the condensate is removed after each step, simulating continuous slag removal from the MHD system. MHDGAS retains the condensate for each step, simulating flow of condensate (and gas) through the MHD system.

  20. A Proposal for a Dimensional Classification System Based on the Shared Features of the "DSM-IV" Anxiety and Mood Disorders: Implications for Assessment and Treatment

    Science.gov (United States)

    Brown, Timothy A.; Barlow, David H.

    2009-01-01

    A wealth of evidence attests to the extensive current and lifetime diagnostic comorbidity of the "Diagnostic and Statistical Manual of Mental Disorders" (4th ed., "DSM-IV") anxiety and mood disorders. Research has shown that the considerable cross-sectional covariation of "DSM-IV" emotional disorders is accounted for by common higher order…

  1. CHARACTERIZING THE COOL KOIs. IV. KEPLER-32 AS A PROTOTYPE FOR THE FORMATION OF COMPACT PLANETARY SYSTEMS THROUGHOUT THE GALAXY

    International Nuclear Information System (INIS)

    Swift, Jonathan J.; Johnson, John Asher; Morton, Timothy D.; Montet, Benjamin T.; Muirhead, Philip S.; Crepp, Justin R.; Fabrycky, Daniel C.

    2013-01-01

    The Kepler space telescope has opened new vistas in exoplanet discovery space by revealing populations of Earth-sized planets that provide a new context for understanding planet formation. Approximately 70% of all stars in the Galaxy belong to the diminutive M dwarf class, several thousand of which lie within Kepler's field of view, and a large number of these targets show planet transit signals. The Kepler M dwarf sample has a characteristic mass of 0.5 M ☉ representing a stellar population twice as common as Sun-like stars. Kepler-32 is a typical star in this sample that presents us with a rare opportunity: five planets transit this star, giving us an expansive view of its architecture. All five planets of this compact system orbit their host star within a distance one-third the size of Mercury's orbit, with the innermost planet positioned a mere 4.3 stellar radii from the stellar photosphere. New observations limit possible false positive scenarios, allowing us to validate the entire Kepler-32 system making it the richest known system of transiting planets around an M dwarf. Based on considerations of the stellar dust sublimation radius, a minimum mass protoplanetary nebula, and the near period commensurability of three adjacent planets, we propose that the Kepler-32 planets formed at larger orbital radii and migrated inward to their present locations. The volatile content inferred for the Kepler-32 planets and order of magnitude estimates for the disk migration rates suggest that these planets may have formed beyond the snow line and migrated in the presence of a gaseous disk. If true, then this would place an upper limit on their formation time of ∼10 Myr. The Kepler-32 planets are representative of the full ensemble of planet candidates orbiting the Kepler M dwarfs for which we calculate an occurrence rate of 1.0 ± 0.1 planet per star. The formation of the Kepler-32 planets therefore offers a plausible blueprint for the formation of one of the largest

  2. Effector protein translocation by the Coxiella burnetii Dot/Icm type IV secretion system requires endocytic maturation of the pathogen-occupied vacuole.

    Directory of Open Access Journals (Sweden)

    Hayley J Newton

    Full Text Available The human pathogen Coxiella burnetii encodes a type IV secretion system called Dot/Icm that is essential for intracellular replication. The Dot/Icm system delivers bacterial effector proteins into the host cytosol during infection. The effector proteins delivered by C. burnetii are predicted to have important functions during infection, but when these proteins are needed during infection has not been clearly defined. Here, we use a reporter system consisting of fusion proteins that have a β-lactamase enzyme (BlaM fused to C. burnetii effector proteins to study protein translocation by the Dot/Icm system. Translocation of BlaM fused to the effector proteins CBU0077, CBU1823 and CBU1524 was not detected until 8-hours after infection of HeLa cells, which are permissive for C. burnetii replication. Translocation of these effector fusion proteins by the Dot/Icm system required acidification of the Coxiella-containing vacuole. Silencing of the host genes encoding the membrane transport regulators Rab5 or Rab7 interfered with effector translocation, which indicates that effectors are not translocated until bacteria traffic to a late endocytic compartment in the host cell. Similar requirements for effector translocation were discerned in bone marrow macrophages derived from C57BL/6 mice, which are primary cells that restrict the intracellular replication of C. burnetii. In addition to requiring endocytic maturation of the vacuole for Dot/Icm-mediated translocation of effectors, bacterial transcription was required for this process. Thus, translocation of effector proteins by the C. burnetii Dot/Icm system occurs after acidification of the CCV and maturation of this specialized organelle to a late endocytic compartment. This indicates that creation of the specialized vacuole in which C. burnetii replicates represents a two-stage process mediated initially by host factors that regulate endocytic maturation and then by bacterial effectors delivered into

  3. Thermodynamic data for predicting concentrations of Th(IV), U(IV), Np(IV), and Pu(IV) in geologic environments

    Energy Technology Data Exchange (ETDEWEB)

    Rai, Dhanpat; Roa, Linfeng; Weger, H.T.; Felmy, A.R. [Battelle, Pacific Northwest National Laboratory (PNNL) (United States); Choppin, G.R. [Florida State University (United States); Yui, Mikazu [Waste Isolation Research Division, Tokai Works, Japan Nuclear Cycle Development Inst., Tokai, Ibaraki (Japan)

    1999-01-01

    This report provides thermodynamic data for predicting concentrations of Th(IV), U(IV), Np(IV), and Pu(IV) in geologic environments, and contributes to an integration of the JNC chemical thermodynamic database, JNC-TDB (previously PNC-TDB), for the performance analysis of geological isolation system for high-level radioactive wastes. Thermodynamic data for the formation of complexes or compounds with hydroxide, chloride, fluoride, carbonate, nitrate, sulfate and phosphate are discussed in this report. Where data for specific actinide(IV) species was lacking, the data were selected based on chemical analogy to other tetravalent actinides. In this study, the Pitzer ion-interaction model is used to extrapolate thermodynamic constants to zero ionic strength at 25degC. (author)

  4. Problems of the Starting and Operating of Hydraulic Components and Systems in Low Ambient Temperature (Part IV

    Directory of Open Access Journals (Sweden)

    Jasiński Ryszard

    2017-09-01

    Full Text Available Designers of hydraulically driven machines and devices are obliged to ensure during design process their high service life with taking into account their operational conditions. Some of the machines may be started in low ambient temperature and even in thermal shock conditions (due to delivering hot working medium to cold components. In order to put such devices into operation appropriate investigations, including experimental ones - usually very expensive and time-consuming, are carried out. For this reason numerical calculations can be used to determine serviceability of a hydraulic component or system operating in thermal shock conditions. Application of numerical calculation methods is much less expensive in comparison to experimental ones. This paper presents a numerical calculation method which makes it possible to solve issues of heat exchange in elements of investigated hydraulic components by using finite elements method. For performing the simulations the following data are necessary: ambient temperature, oil temperature, heat transfer coefficient between oil and surfaces of elements, as well as areas of surfaces being in contact with oil. By means of computer simulation method values of clearance between cooperating elements as well as ranges of parameters of correct and incorrect operation of hydraulic components have been determined. In this paper results of computer simulation of some experimentally tested hydraulic components such as axial piston pump and proportional spool valve, are presented. The computer simulation results were compared with the experimental ones and high conformity was obtained.

  5. Kepler eclipsing binary stars. IV. Precise eclipse times for close binaries and identification of candidate three-body systems

    International Nuclear Information System (INIS)

    Conroy, Kyle E.; Stassun, Keivan G.; Prša, Andrej; Orosz, Jerome A.; Welsh, William F.; Fabrycky, Daniel C.

    2014-01-01

    We present a catalog of precise eclipse times and analysis of third-body signals among 1279 close binaries in the latest Kepler Eclipsing Binary Catalog. For these short-period binaries, Kepler's 30 minute exposure time causes significant smearing of light curves. In addition, common astrophysical phenomena such as chromospheric activity, as well as imperfections in the light curve detrending process, can create systematic artifacts that may produce fictitious signals in the eclipse timings. We present a method to measure precise eclipse times in the presence of distorted light curves, such as in contact and near-contact binaries which exhibit continuously changing light levels in and out of eclipse. We identify 236 systems for which we find a timing variation signal compatible with the presence of a third body. These are modeled for the light travel time effect and the basic properties of the third body are derived. This study complements J. A. Orosz et al. (in preparation), which focuses on eclipse timing variations of longer period binaries with flat out-of-eclipse regions. Together, these two papers provide comprehensive eclipse timings for all binaries in the Kepler Eclipsing Binary Catalog, as an ongoing resource freely accessible online to the community.

  6. Final Report for the Testing of the Y-12 Criticality Accident Alarm System Detectors at the Godiva IV Burst Reactor (IER-443)

    Energy Technology Data Exchange (ETDEWEB)

    Scorby, John C. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Hickman, David [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Hudson, Becka [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Beller, Tim [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Goda, Joetta [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Haught, Chris [Y-12 National Security Complex, Oak Ridge, TN (United States); Woodrow, Christopher [Y-12 National Security Complex, Oak Ridge, TN (United States); Ward, Dann [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Wilson, Chris [Atomic Weapons Establishment (AWE), Berkshire (United Kingdom); Clark, Leo [Atomic Weapons Establishment (AWE), Berkshire (United Kingdom)

    2018-01-05

    This report documents the experimental conditions and final results for the performance testing of the Y-12 Criticality Accident Alarm System (CAAS) detectors at the Godiva IV Burst Reactor at the National Criticality Experimental Research Center (NCERC) at the Nevada National Security Site (NNSS). The testing followed a previously issued test plan and was conducted during the week of July 17, 2017, with completion on Thursday July 20. The test subjected CAAS detectors supplied by Y-12 to very intense and short duration mixed neutron and gamma radiation fields to establish compliance to maximum radiation and minimum pulse width requirements. ANSI/ANS- 8.3.1997 states that the “system shall be sufficiently robust as to actuate an alarm signal when exposed to the maximum radiation expected”, which has been defined at Y-12, in Documented Safety Analyses (DSAs), to be a dose rate of 10 Rad/s. ANSI/ANS-8.3.1997 further states that “alarm actuation shall occur as a result of a minimum duration transient” which may be assumed to be 1 msec. The pulse widths and dose rates provided by each burst during the test exceeded those requirements. The CAAS detectors all provided an immediate alarm signal and remained operable after the bursts establishing compliance to the requirements and fitness for re-deployment at Y-12.

  7. IV&V Project Assessment Process Validation

    Science.gov (United States)

    Driskell, Stephen

    2012-01-01

    The Space Launch System (SLS) will launch NASA's Multi-Purpose Crew Vehicle (MPCV). This launch vehicle will provide American launch capability for human exploration and travelling beyond Earth orbit. SLS is designed to be flexible for crew or cargo missions. The first test flight is scheduled for December 2017. The SLS SRR/SDR provided insight into the project development life cycle. NASA IV&V ran the standard Risk Based Assessment and Portfolio Based Risk Assessment to identify analysis tasking for the SLS program. This presentation examines the SLS System Requirements Review/System Definition Review (SRR/SDR), IV&V findings for IV&V process validation correlation to/from the selected IV&V tasking and capabilities. It also provides a reusable IEEE 1012 scorecard for programmatic completeness across the software development life cycle.

  8. IV access in dental practice.

    LENUS (Irish Health Repository)

    Fitzpatrick, J J

    2009-04-01

    Intravenous (IV) access is a valuable skill for dental practitioners in emergency situations and in IV sedation. However, many people feel some apprehension about performing this procedure. This article explains the basic principles behind IV access, and the relevant anatomy and physiology, as well as giving a step-by-step guide to placing an IV cannula.

  9. What is good sport: Plato's view Co je to dobrý sport: Platónův pohled

    Directory of Open Access Journals (Sweden)

    Jernej Pisk

    2006-02-01

    Full Text Available One of Plato's most common questions found in his dialogues is "What is something?" By asking this question Plato usually brought his co-speakers to the recognition that in fact they do not have a full comprehension of what something is, although they have a partial comprehension of it. The awareness of one's incomplete cognition is the first step to be made on the philosophic way to truth. As in ancient times also today Plato asks us – the modern philosophers of sport – "What is sport?" or more precisely "What is good sport?" Probably the best of Plato's answers to this question can be found in the basic concepts of his philosophy regarding his hierarchical division of the state and human soul into three parts. Since sport is derived from human being also the goodness of sport can be divided into three stages. The lowest stage of sport corresponds to the first part of the soul – the appetite soul. On this stage sport is based on the gaining of material goods through prizes won at competitions. In the philosophic view, this is the lowest possible stage of goodness of sport. The second stage of sport corresponds to the second part of the soul – the emotional soul. Sport at this stage is based on the elementary ancient agon, which seeks fulfilment in the winning of honour and glory. The greatest and the most superior is the third part of the soul – the reasonable soul. According to this, also the sport corresponding to the third part of the soul is the best. For this kind of sport it is no longer necessary to compete with other contestants, since it can achieve it's fulfilment in perfect execution of movement or exercise, in which the perfect cooperation between reason (soul and body is attained. At this stage of sport it is the most important to compete and win over one's self, and this can be achieved by everyone, without regard to his/her physical abilities in comparison with others. In Plato's view, good sport is the sport directed

  10. Identification of VceA and VceC, two members of the VjbR regulon that are translocated into macrophages by the Brucella type IV secretion system

    NARCIS (Netherlands)

    de Jong, Maarten F.; Sun, Yao-Hui; den Hartigh, Andreas B.; van Dijl, Jan Maarten; Tsolis, Renee M.

    2008-01-01

    Survival and replication inside host cells by Brucella spp. requires a type IV secretion system (T4SS), encoded by the virB locus. However, the identity of the molecules secreted by the T4SS has remained elusive. We hypothesized that proteins translocated by the T4SS would be co-regulated with the

  11. Uranium (IV) carboxylates - I

    Energy Technology Data Exchange (ETDEWEB)

    Satpathy, K C; Patnaik, A K [Sambalpur Univ. (India). Dept. of Chemistry

    1975-11-01

    A few uranium(IV) carboxylates with monochloro and trichloro acetic acid, glycine, malic, citric, adipic, o-toluic, anthranilic and salicylic acids have been prepared by photolytic methods. The I.R. spectra of these compounds are recorded and basing on the spectral data, structure of the compounds have been suggested.

  12. Thermodynamic characteristics of systems with solid solutions composed of crystal hydrates of lanthanide and yttrium chlorides, at 250C. III. Systems of Roozeboom's type IV, with restricted solid solutions

    International Nuclear Information System (INIS)

    Sokolova, N.P.

    1983-01-01

    The values of the activity, the activity coefficients, the free energy of mixing and the excess free energy of mixing have been calculated for CeCl 3 -LnCl 3 -H 2 O systems (where Ln identical with Sm, Gd, Dy, Ho, Er, Y) containing solid solutions of types IV and IVa. It is shown that the stability of the solid solutions decreases with increasing difference between the radii of the cations of cerium and the second lanthanide, which enter into the composition of the components of the solid solutions. The factors determining the composition of a liquid solution corresponding to the eutonic point are specified

  13. Investigation of the system ThO2-NpO2-P2O5. Solid solutions of thorium-neptunium (IV) phosphate-diphosphate

    International Nuclear Information System (INIS)

    Dacheux, N.; Thomas, A.C.; Brandel, V.; Genet, M.

    1998-01-01

    Considering that phosphate matrices could be potential candidates for the immobilization of actinides or for the final disposal of the excess plutonium from dismantled nuclear weapons, the chemistry of thorium phosphates has been re-examined. In the ThO 2 -P 2 O 5 system, the thorium phosphate-diphosphate Th 4 (PO 4 ) 4 P 2 O 7 (TPD) can be synthesized by wet and dry chemical processes. The substitution of thorium by other tetravalent actinides like uranium or plutonium can be obtained for 0 4-x Np x (PO 4 ) 4 P 2 O 7 (TNPD) with 0 4+ by Np 4+ in the TPD structure is evaluated to 2.08 (which corresponds to about 52 mol% of thorium replaced by neptunium (IV)). The field of existence of solid solutions Th 4-x U -x Np -x Pu U x U Np x Np Pu x Pu (PO 4 )4P 2 O 7 has been calculated. These solid solutions should be synthesized for 5x U +7x Np +9x Pu ≤15. In the NpO 2 -P 2 O 5 system, the unit cell parameters of Np 2 O(PO 4 ) 2 were refined by analogy with U 2 O(PO 4 ) 2 which crystallographic data have been published recently. For Np 2 O(PO 4 ) 2 the unit cell is orthorhombic with the following cell parameters: a=7.033(2)A, b=9.024(3)A, c=12.587(6)A and V=799(1)A 3 . The unit cell parameter obtained for α-NpP 2 O 7 (a=8.586(1)A) is in good agreement with those already reported in literature. (orig.)

  14. Enhanced Design Alternative IV

    International Nuclear Information System (INIS)

    Kramer, N.E.

    1999-01-01

    This report evaluates Enhanced Design Alternative (EDA) IV as part of the second phase of the License Application Design Selection (LADS) effort. The EDA IV concept was compared to the VA reference design using criteria from the Design Input Request for LADS Phase II EDA Evaluations (CRWMS M and O 1999b) and (CRWMS M and O 1999f). Briefly, the EDA IV concept arranges the waste packages close together in an emplacement configuration known as line load. Continuous pre-closure ventilation keeps the waste packages from exceeding their 350 C cladding and 200 C (4.3.6) drift wall temperature limits. This EDA concept keeps relatively high, uniform emplacement drift temperatures (post-closure) to drive water away from the repository and thus dry out the pillars between emplacement drifts. The waste package is shielded to permit human access to emplacement drifts and includes an integral filler inside the package to reduce the amount of water that can contact the waste form. Closure of the repository is desired 50 years after first waste is emplaced. Both backfill and drip shields will be emplaced at closure to improve post-closure performance. The EDA IV concept includes more defense-in-depth layers than the VA reference design because of its backfill, drip shield, waste package shielding, and integral filler features. These features contribute to the low dose-rate to the public achieved during the first 10,000 years of repository life as shown in Figure 3. Investigation of the EDA IV concept has led to the following general conclusions: (1) The total life cycle cost for EDA IV is about $21.7 billion which equates to a $11.3 billion net present value (both figures rounded up). (2) The incidence of design basis events for EDA IV is similar to the VA reference design. (3) The emplacement of the waste packages in drifts will be similar to the VA reference design. However, heavier equipment may be required because the shielded waste package will be heavier. (4) The heavier

  15. An optimal set of features for predicting type IV secretion system effector proteins for a subset of species based on a multi-level feature selection approach.

    Directory of Open Access Journals (Sweden)

    Zhila Esna Ashari

    Full Text Available Type IV secretion systems (T4SS are multi-protein complexes in a number of bacterial pathogens that can translocate proteins and DNA to the host. Most T4SSs function in conjugation and translocate DNA; however, approximately 13% function to secrete proteins, delivering effector proteins into the cytosol of eukaryotic host cells. Upon entry, these effectors manipulate the host cell's machinery for their own benefit, which can result in serious illness or death of the host. For this reason recognition of T4SS effectors has become an important subject. Much previous work has focused on verifying effectors experimentally, a costly endeavor in terms of money, time, and effort. Having good predictions for effectors will help to focus experimental validations and decrease testing costs. In recent years, several scoring and machine learning-based methods have been suggested for the purpose of predicting T4SS effector proteins. These methods have used different sets of features for prediction, and their predictions have been inconsistent. In this paper, an optimal set of features is presented for predicting T4SS effector proteins using a statistical approach. A thorough literature search was performed to find features that have been proposed. Feature values were calculated for datasets of known effectors and non-effectors for T4SS-containing pathogens for four genera with a sufficient number of known effectors, Legionella pneumophila, Coxiella burnetii, Brucella spp, and Bartonella spp. The features were ranked, and less important features were filtered out. Correlations between remaining features were removed, and dimensional reduction was accomplished using principal component analysis and factor analysis. Finally, the optimal features for each pathogen were chosen by building logistic regression models and evaluating each model. The results based on evaluation of our logistic regression models confirm the effectiveness of our four optimal sets of

  16. Iron Starvation Conditions Upregulate Ehrlichia ruminantium Type IV Secretion System, tr1 Transcription Factor and map1 Genes Family through the Master Regulatory Protein ErxR

    Directory of Open Access Journals (Sweden)

    Amal Moumène

    2018-01-01

    Full Text Available Ehrlichia ruminantium is an obligatory intracellular bacterium that causes heartwater, a fatal disease in ruminants. Due to its intracellular nature, E. ruminantium requires a set of specific virulence factors, such as the type IV secretion system (T4SS, and outer membrane proteins (Map proteins in order to avoid and subvert the host's immune response. Several studies have been conducted to understand the regulation of the T4SS or outer membrane proteins, in Ehrlichia, but no integrated approach has been used to understand the regulation of Ehrlichia pathogenicity determinants in response to environmental cues. Iron is known to be a key nutrient for bacterial growth both in the environment and within hosts. In this study, we experimentally demonstrated the regulation of virB, map1, and tr1 genes by the newly identified master regulator ErxR (for Ehrlichia ruminantium expression regulator. We also analyzed the effect of iron depletion on the expression of erxR gene, tr1 transcription factor, T4SS and map1 genes clusters in E. ruminantium. We show that exposure of E. ruminantium to iron starvation induces erxR and subsequently tr1, virB, and map1 genes. Our results reveal tight co-regulation of T4SS and map1 genes via the ErxR regulatory protein at the transcriptional level, and, for the first time link map genes to the virulence function sensu stricto, thereby advancing our understanding of Ehrlichia's infection process. These results suggest that Ehrlichia is able to sense changes in iron concentrations in the environment and to regulate the expression of virulence factors accordingly.

  17. Helicobacter pylori Type IV Secretion System and Its Adhesin Subunit, CagL, Mediate Potent Inflammatory Responses in Primary Human Endothelial Cells

    Directory of Open Access Journals (Sweden)

    Mona Tafreshi

    2018-02-01

    Full Text Available The Gram-negative bacterium, Helicobacter pylori, causes chronic gastritis, peptic ulcers, and gastric cancer in humans. Although the gastric epithelium is the primary site of H. pylori colonization, H. pylori can gain access to deeper tissues. Concurring with this notion, H. pylori has been found in the vicinity of endothelial cells in gastric submucosa. Endothelial cells play crucial roles in innate immune response, wound healing and tumorigenesis. This study examines the molecular mechanisms by which H. pylori interacts with and triggers inflammatory responses in endothelial cells. We observed that H. pylori infection of primary human endothelial cells stimulated secretion of the key inflammatory cytokines, interleukin-6 (IL-6 and interleukin-8 (IL-8. In particular, IL-8, a potent chemokine and angiogenic factor, was secreted by H. pylori-infected endothelial cells to levels ~10- to 20-fold higher than that typically observed in H. pylori-infected gastric epithelial cells. These inflammatory responses were triggered by the H. pylori type IV secretion system (T4SS and the T4SS-associated adhesin CagL, but not the translocation substrate CagA. Moreover, in contrast to integrin α5β1 playing an essential role in IL-8 induction by H. pylori upon infection of gastric epithelial cells, both integrin α5β1 and integrin αvβ3 were dispensable for IL-8 induction in H. pylori-infected endothelial cells. However, epidermal growth factor receptor (EGFR is crucial for mediating the potent H. pylori-induced IL-8 response in endothelial cells. This study reveals a novel mechanism by which the H. pylori T4SS and its adhesin subunit, CagL, may contribute to H. pylori pathogenesis by stimulating the endothelial innate immune responses, while highlighting EGFR as a potential therapeutic target for controlling H. pylori-induced inflammation.

  18. Evolutionary Dynamics of Pathoadaptation Revealed by Three Independent Acquisitions of the VirB/D4 Type IV Secretion System in Bartonella.

    Science.gov (United States)

    Harms, Alexander; Segers, Francisca H I D; Quebatte, Maxime; Mistl, Claudia; Manfredi, Pablo; Körner, Jonas; Chomel, Bruno B; Kosoy, Michael; Maruyama, Soichi; Engel, Philipp; Dehio, Christoph

    2017-03-01

    The α-proteobacterial genus Bartonella comprises a group of ubiquitous mammalian pathogens that are studied as a model for the evolution of bacterial pathogenesis. Vast abundance of two particular phylogenetic lineages of Bartonella had been linked to enhanced host adaptability enabled by lineage-specific acquisition of a VirB/D4 type IV secretion system (T4SS) and parallel evolution of complex effector repertoires. However, the limited availability of genome sequences from one of those lineages as well as other, remote branches of Bartonella has so far hampered comprehensive understanding of how the VirB/D4 T4SS and its effectors called Beps have shaped Bartonella evolution. Here, we report the discovery of a third repertoire of Beps associated with the VirB/D4 T4SS of B. ancashensis, a novel human pathogen that lacks any signs of host adaptability and is only distantly related to the two species-rich lineages encoding a VirB/D4 T4SS. Furthermore, sequencing of ten new Bartonella isolates from under-sampled lineages enabled combined in silico analyses and wet lab experiments that suggest several parallel layers of functional diversification during evolution of the three Bep repertoires from a single ancestral effector. Our analyses show that the Beps of B. ancashensis share many features with the two other repertoires, but may represent a more ancestral state that has not yet unleashed the adaptive potential of such an effector set. We anticipate that the effectors of B. ancashensis will enable future studies to dissect the evolutionary history of Bartonella effectors and help unraveling the evolutionary forces underlying bacterial host adaptation. © The Author(s) 2017. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

  19. Current status of NPP generation IV

    International Nuclear Information System (INIS)

    Yohanes Dwi Anggoro; Dharu Dewi; Nurlaila; Arief Tris Yuliyanto

    2013-01-01

    Today development of nuclear technology has reached the stage of research and development of Generation IV nuclear power plants (advanced reactor systems) which is an innovative development from the previous generation of nuclear power plants. There are six types of power generation IV reactors, namely: Very High Temperature Reactor (VHTR), Sodium-cooled Fast Reactor (SFR), Gas-cooled Fast Reactor (GFR), Lead-cooled Fast Reactor (LFR), Molten Salt Reactor (MSR), and Super Critical Water-cooled Reactor (SCWR). The purpose of this study is to know the development of Generation IV nuclear power plants that have been done by the thirteen countries that are members of the Gen IV International Forum (GIF). The method used is review study and refers to various studies related to the current status of research and development of generation IV nuclear power. The result of this study showed that the systems and technology on Generation IV nuclear power plants offer significant advances in sustainability, safety and reliability, economics, and proliferation resistance and physical protection. In addition, based on the research and development experience is estimated that: SFR can be used optimally in 2015, VHTR in 2020, while NPP types GFR, LFR, MSR, and SCWR in 2025. Utilization of NPP generation IV said to be optimal if fulfill the goal of NPP generation IV, such as: capable to generate energy sustainability and promote long-term availability of nuclear fuel, minimize nuclear waste and reduce the long term stewardship burden, has an advantage in the field of safety and reliability compared to the previous generation of NPP and VHTR technology have a good prospects in Indonesia. (author)

  20. A sputnik IV saga

    Science.gov (United States)

    Lundquist, Charles A.

    2009-12-01

    The Sputnik IV launch occurred on May 15, 1960. On May 19, an attempt to deorbit a 'space cabin' failed and the cabin went into a higher orbit. The orbit of the cabin was monitored and Moonwatch volunteer satellite tracking teams were alerted to watch for the vehicle demise. On September 5, 1962, several team members from Milwaukee, Wisconsin made observations starting at 4:49 a.m. of a fireball following the predicted orbit of Sputnik IV. Requests went out to report any objects found under the fireball path. An early morning police patrol in Manitowoc had noticed a metal object on a street and had moved it to the curb. Later the officers recovered the object and had it dropped off at the Milwaukee Journal. The Moonwarch team got the object and reported the situation to Moonwatch Headquarters at the Smithsonian Astrophysical Observatory. A team member flew to Cambridge with the object. It was a solid, 9.49 kg piece of steel with a slag-like layer attached to it. Subsequent analyses showed that it contained radioactive nuclei produced by cosmic ray exposure in space. The scientists at the Observatory quickly recognized that measurements of its induced radioactivity could serve as a calibration for similar measurements of recently fallen nickel-iron meteorites. Concurrently, the Observatory directorate informed government agencies that a fragment from Sputnik IV had been recovered. Coincidently, a debate in the UN Committee on Peaceful Uses of Outer Space involved the issue of liability for damage caused by falling satellite fragments. On September 12, the Observatory delivered the bulk of the fragment to the US Delegation to the UN. Two days later, the fragment was used by US Ambassador Francis Plimpton as an exhibit that the time had come to agree on liability for damage from satellite debris. He offered the Sputnik IV fragment to USSR Ambassador P.D. Morozov, who refused the offer. On October 23, Drs. Alla Massevitch and E.K. Federov of the USSR visited the

  1. Cardiovascular events in acute coronary syndrome patients with peripheral arterial disease treated with ticagrelor compared to clopidogrel: Data from the PLATO trials

    DEFF Research Database (Denmark)

    Patel, Manesh R.; Becker, Richard C.; Wojdyla, Daniel M.

    Abstract 14299: Cardiovascular Events in Acute Coronary Syndrome Patients With Peripheral Arterial Disease Treated With Ticagrelor Compared to Clopidogrel: Data From the PLATO Trial Manesh R Patel1; Richard C Becker1; Daniel M Wojdyla2; Håkan Emanuelsson3; William Hiatt4; Jay Horrow5; Steen Husted6...... Uppsala, Sweden 10 Cardiology, Uppsala Clinical Rsch center, 75185 Uppsala, Sweden Background: Patients with peripheral artery disease (PAD) and acute coronary syndrome (ACS) are at high risk for clinical events and are often difficult to manage. We evaluated cardiovascular outcomes of ACS patients...

  2. Bartonella henselae trimeric autotransporter adhesin BadA expression interferes with effector translocation by the VirB/D4 type IV secretion system.

    Science.gov (United States)

    Lu, Yun-Yueh; Franz, Bettina; Truttmann, Matthias C; Riess, Tanja; Gay-Fraret, Jérémie; Faustmann, Marco; Kempf, Volkhard A J; Dehio, Christoph

    2013-05-01

    The Gram-negative, zoonotic pathogen Bartonella henselae is the aetiological agent of cat scratch disease, bacillary angiomatosis and peliosis hepatis in humans. Two pathogenicity factors of B. henselae - each displaying multiple functions in host cell interaction - have been characterized in greater detail: the trimeric autotransporter Bartonella adhesin A (BadA) and the type IV secretion system VirB/D4 (VirB/D4 T4SS). BadA mediates, e.g. binding to fibronectin (Fn), adherence to endothelial cells (ECs) and secretion of vascular endothelial growth factor (VEGF). VirB/D4 translocates several Bartonella effector proteins (Beps) into the cytoplasm of infected ECs, resulting, e.g. in uptake of bacterial aggregates via the invasome structure, inhibition of apoptosis and activation of a proangiogenic phenotype. Despite this knowledge of the individual activities of BadA or VirB/D4 it is unknown whether these major virulence factors affect each other in their specific activities. In this study, expression and function of BadA and VirB/D4 were analysed in a variety of clinical B. henselae isolates. Data revealed that most isolates have lost expression of either BadA or VirB/D4 during in vitro passages. However, the phenotypic effects of coexpression of both virulence factors was studied in one clinical isolate that was found to stably coexpress BadA and VirB/D4, as well as by ectopic expression of BadA in a strain expressing VirB/D4 but not BadA. BadA, which forms a dense layer on the bacterial surface, negatively affected VirB/D4-dependent Bep translocation and invasome formation by likely preventing close contact between the bacterial cell envelope and the host cell membrane. In contrast, BadA-dependent Fn binding, adhesion to ECs and VEGF secretion were not affected by a functional VirB/D4 T4SS. The obtained data imply that the essential virulence factors BadA and VirB/D4 are likely differentially expressed during different stages of the infection cycle of

  3. Progress in the development of the neutron flux monitoring system of the French GEN-IV SFR: simulations and experimental validations [ANIMMA--2015-IO-392

    Energy Technology Data Exchange (ETDEWEB)

    Jammes, C.; Filliatre, P.; Izarra, G. de [CEA, DEN, Cadarache, Reactor Studies Department, 13108 Saint-Paul-lez-Durance (France); Elter, Zs. [CEA, DEN, Cadarache, Reactor Studies Department, 13108 Saint-Paul-lez-Durance (France); Chalmers University of Technology, Department of Applied Physics, Division of Nuclear Engineering, SE-412 96 Goeteborg (Sweden); Verma, V. [CEA, DEN, Cadarache, Reactor Studies Department, 13108 Saint-Paul-lez-Durance (France); Uppsala University, Division of Applied Nuclear Physics, Box 516, SE-75120 Uppsala (Sweden); Hamrita, H.; Bakkali, M. [CEA, DRT, LIST, Metrology, Instrumentation and Information Department, Saclay, 91191 Gif-sur-Yvette (France); Chapoutier, N.; Scholer, A.C.; Verrier, D. [AREVA NP, 10 rue Juliette Recamier F-69456 Lyon (France); Hellesen, C.; Jacobsson, S. [Uppsala University, Division of Applied Nuclear Physics, Box 516, SE-75120 Uppsala (Sweden); Pazsit, I. [Chalmers University of Technology, Department of Applied Physics, Division of Nuclear Engineering, SE-412 96 Goeteborg (Sweden); Cantonnet, B.; Nappe, J.C. [PHOTONIS France, Nuclear Instrumentation, 19100 Brive-la-Gaillarde (France); Molinie, P.; Dessante, P.; Hanna, R.; Kirkpatrick, M.; Odic, E. [Supelec, Energy Department, 3 rue Joliot-Curie, 91191 Gif-sur-Yvette (France)

    2015-07-01

    France has a long experience of about 50 years in designing, building and operating sodium-cooled fast reactors (SFR) such as RAPSODIE, PHENIX and SUPER PHENIX. Fast reactors feature the double capability of reducing nuclear waste and saving nuclear energy resources by burning actinides. Since this reactor type is one of those selected by the Generation IV International Forum, the French government asked, in the year 2006, CEA, namely the French Alternative Energies and Atomic Energy Commission, to lead the development of an innovative GEN-IV nuclear- fission power demonstrator. The major objective is to improve the safety and availability of an SFR. The neutron flux monitoring (NFM) system of any reactor must, in any situation, permit both reactivity control and power level monitoring from startup to full power. It also has to monitor possible changes in neutron flux distribution within the core region in order to prevent any local melting accident. The neutron detectors will have to be installed inside the reactor vessel because locations outside the vessel will suffer from severe disadvantages; radially the neutron shield that is also contained in the reactor vessel will cause unacceptable losses in neutron flux; below the core the presence of a core-catcher prevents from inserting neutron guides; and above the core the distance is too large to obtain decent neutron signals outside the vessel. Another important point is to limit the number of detectors placed in the vessel in order to alleviate their installation into the vessel. In this paper, we show that the architecture of the NFM system will rely on high-temperature fission chambers (HTFC) featuring wide-range flux monitoring capability. The definition of such a system is presented and the justifications of technological options are brought with the use of simulation and experimental results. Firstly, neutron-transport calculations allow us to propose two in-vessel regions, namely the above-core and under

  4. Magnetic resonance imaging assessment of the ventricular system in the brains of adult and juvenile beagle dogs treated with posaconazole IV Solution.

    Science.gov (United States)

    Hines, C D G; Song, X; Kuruvilla, S; Farris, G; Markgraf, C G

    2015-01-01

    Noxafil® (posaconazole; POS) is a potent, selective triazole antifungal approved for use in adults as an oral suspension, oral tablet and intravenous (IV) Solution. In support of pediatric administration of POS IV Solution to childrentwo years of age, two studies were undertaken using magnetic resonance imaging (MRI) to monitor brain ventricle size longitudinally during three months administration of POS IV in adult and juvenile dogs. Necropsy was performed on all animals at the end of the studies. From the baseline MRI images, great variability in ventricle size was noted in both the adult and juvenile dogs; these images were used to distribute differently sized ventricles between treatment and vehicle groups as to not skew group means during the course of the study. POS IV Solution had no effect on ventricle volume at any timepoint during dosing in either the adult or the juvenile dogs. Further, no gross or histomorphologic differences between groups were observed in either study. Compared to juvenile dogs, MRI analysis showed that adult dogs had larger ventricles, lower variability in all ventricle volumes, and a greater rate of increase in total ventricle volume. Information on growth and development of brains is one of the few areas in which more detailed information is available about humans than about the standard laboratory animals used to model disease and predict toxicities. The use of MRI helped elucidate large natural variabilities in the dog brain, which could have altered the interpretation of this de-risking study, and provided a valuable noninvasive means to monitor the brain ventricles longitudinally. Copyright © 2015 Elsevier Inc. All rights reserved.

  5. Inverse break-through investigation on uranium isotope separation in the system Fe(III) water-glycerine solution-U(IV) cathionic resin

    International Nuclear Information System (INIS)

    Murgulescu, Sanda; Calusaru, A.

    1977-01-01

    When a solution containing ferric ions passes on cationic resin in U(IV) form, the substitution of uranium by iron is preceded by oxydation of U(IV) to U(VI). During the contact of U(VI) in solution with U(IV) in resin, an exchange reaction occurs, in which 235 U is slightly concentrated in solution and 238 U in resin phase. Since increase of temperature accelerates the exchange reaction, the apparent thermodynamic values of the exchange reaction were calculated, by taking into account the variation of the apparent equilibrium constant as a function of the reciprocal value of the temperature. The corresponding thermodynamic values in both pure aqueous and water-glycerine solution are: ΔH 0 =6.45 cal.mol -1 and ΔS 0 =21.6x10 -3 cal. 0 K -1 . The use of glycerine containing solutions offers the important advantage to increase the stability versus hydrolysis of the ferric ions even at higher temperature

  6. An Examination of a Proposed DSM-IV Pathological Gambling Hierarchy in a Treatment Seeking Population: Similarities with Substance Dependence and Evidence for Three Classification Systems.

    Science.gov (United States)

    Christensen, Darren R; Jackson, Alun C; Dowling, Nicki A; Volberg, Rachel A; Thomas, Shane A

    2015-09-01

    Toce-Gerstein et al. (Addiction 98:1661-1672, 2003) investigated the distribution of Diagnostic and Statistical Manual for Mental Disorders, 4th edition (DSM-IV) pathological gambling criteria endorsement in a U.S. community sample for those people endorsing a least one of the DSM-IV criteria (n = 399). They proposed a hierarchy of gambling disorders where endorsement of 1-2 criteria were deemed 'At-Risk', 3-4 'Problem gamblers', 5-7 'Low Pathological', and 8-10 'High Pathological' gamblers. This article examines these claims in a larger Australian treatment seeking population. Data from 4,349 clients attending specialist problem gambling services were assessed for meeting the ten DSM-IV pathological gambling criteria. Results found higher overall criteria endorsement frequencies, three components, a direct relationship between criteria endorsement and gambling severity, clustering of criteria similar to the Toce-Gerstein et al. taxonomy, high accuracy scores for numerical and criteria specific taxonomies, and also high accuracy scores for dichotomous pathological gambling diagnoses. These results suggest significant complexities in the frequencies of criteria reports and relationships between criteria.

  7. Hepatic imaging in stage IV-S neuroblastoma

    International Nuclear Information System (INIS)

    Franken, E.A. Jr.; Smith, W.L.; Iowa Univ., Iowa City; Cohen, M.D.; Kisker, C.T.; Platz, C.E.

    1986-01-01

    Stage IV-S neuroblastoma describes a group of infants with tumor spread limited to liver, skin, or bone marrow. Such patients, who constitute about 25% of affected infants with neuroblastoma, may expect spontaneous tumor remission. We report 18 infants with Stage IV-S neuroblastoma, 83% of whom had liver involvement. Imaging investigations included Technetium 99m sulfur colloid scan, ultrasound, and CT. Two patterns of liver metastasis were noted: ill-defined nodules or diffuse tumor throughout the liver. Distinction of normal and abnormal liver with diffuse type metastasis could be quite difficult, particularly with liver scans. We conclude that patients with Stage IV-S neuroblastoma have ultrasound or CT examination as an initial workup, with nuclear medicine scans reserved for followup studies. (orig.)

  8. Diaquatetrabromidotin(IV trihydrate

    Directory of Open Access Journals (Sweden)

    Fei Ye

    2012-09-01

    Full Text Available The title compound, [SnBr4(H2O2]·3H2O, forms large colourless crystals in originally sealed samples of tin tetrabromide. It constitutes the first structurally characterized hydrate of SnBr4 and is isostructural with the corresponding hydrate of SnCl4. It is composed of SnIV atoms octahedrally coordinated by four Br atoms and two cis-related water molecules. The octahedra exhibit site symmetry 2. They are arranged into columns along [001] via medium–strong O—H...O hydrogen bonds involving the two lattice water molecules (one situated on a twofold rotation axis while the chains are interconnected via longer O—H...Br hydrogen bonds, forming a three-dimensional network.

  9. An enhanced cerium(IV)-rhodamine 6G chemiluminescence system using guest-host interactions in a lab-on-a-chip platform for estimating the total phenolic content in food samples.

    Science.gov (United States)

    Al Haddabi, Buthaina; Al Lawati, Haider A J; Suliman, FakhrEldin O

    2016-04-01

    Two chemiluminescence-microfluidic (CL-MF) systems, e.g., Ce(IV)-rhodamine B (RB) and Ce(IV)-rhodamine 6G (R6G), for the determination of the total phenolic content in teas and some sweeteners were evaluated. The results indicated that the Ce(IV)-R6G system was more sensitive in comparison to the Ce(IV)-RB CL system. Therefore, a simple (CL-MF) method based on the CL of Ce(IV)-R6G was developed, and the sensitivity, selectivity and stability of this system were evaluated. Selected phenolic compounds (PCs), such as quercetin (QRC), catechin (CAT), rutin (RUT), gallic acid (GA), caffeic acid (CA) and syringic acid (SA), produced analytically useful chemiluminescence signals with low detection limits ranging from 0.35 nmol L(-1) for QRC to 11.31 nmol L(-1) for SA. The mixing sequence and the chip design were crucial, as the sensitivity and reproducibility could be substantially affected by these two factors. In addition, the anionic surfactant (i.e., sodium dodecyl sulfate (SDS)) can significantly enhance the CL signal intensity by as much as 300% for the QRC solution. Spectroscopic studies indicated that the enhancement was due to a strong guest-host interaction between the cationic R6G molecules and the anionic amphiphilic environment. Other parameters that could affect the CL intensities of the PCs were carefully optimized. Finally, the method was successfully applied to tea and sweetener samples. Six different tea samples exhibited total phenolic/antioxidant levels from 7.32 to 13.5 g per 100g of sample with respect to GA. Four different sweetener samples were also analyzed and exhibited total phenolic/antioxidant levels from 500.9 to 3422.9 mg kg(-1) with respect to GA. The method was selective, rapid and sensitive when used to estimate the total phenolic/antioxidant level, and the results were in good agreement with those reported for honey and tea samples. Copyright © 2015 Elsevier B.V. All rights reserved.

  10. The carbonate complexation of plutonium(IV)

    International Nuclear Information System (INIS)

    Hobart, D.E.; Palmer, P.D.; Newton, T.W.

    1985-01-01

    Plutonium(IV) carbonate complexes are expected to be of particular importance in typical groundwaters at the Yucca Mountain site of the candidate nuclear waste repository being studied by the Nevada Nuclear Waste Storage Investigations Project. The chemistry of these complexes is also important in the areas of nuclear fuel reprocessing and purification, actinide separations, and environmental studies. This report describes initial experiments performed to determine the identity and equilibrium quotients of plutonium(IV) carbonate complexes. These experiments were performed at pH values between 7.2 and 9.6 using a spectrophotometric method. In addition, a brief review of the published literature on Pu(IV) carbonate complexes is presented. Since Pu(IV) exhibits low solubility in the near-neutral pH range, a complex-competition reaction where citrate ligands compete with carbonate ions for the plutonium will be employed. This will permit us to study the pure carbonate system; study the mixed carbonate/citrate system, and confirm and extend the literature work on the pure citrate system. The current experiments have demonstrated the existence of at least three distinct species in the pH region studied. This work will continue in the extended study of the pure citrate system, followed by the investigation of the citrate/carbonate complex/competition reaction. 9 refs., 4 figs., 2 tabs

  11. Painlevé IV coherent states

    International Nuclear Information System (INIS)

    Bermudez, David; Contreras-Astorga, Alonso; Fernández C, David J.

    2014-01-01

    A simple way to find solutions of the Painlevé IV equation is by identifying Hamiltonian systems with third-order differential ladder operators. Some of these systems can be obtained by applying supersymmetric quantum mechanics (SUSY QM) to the harmonic oscillator. In this work, we will construct families of coherent states for such subset of SUSY partner Hamiltonians which are connected with the Painlevé IV equation. First, these coherent states are built up as eigenstates of the annihilation operator, then as displaced versions of the extremal states, both involving the related third-order ladder operators, and finally as extremal states which are also displaced but now using the so called linearized ladder operators. To each SUSY partner Hamiltonian corresponds two families of coherent states: one inside the infinite subspace associated with the isospectral part of the spectrum and another one in the finite subspace generated by the states created through the SUSY technique. - Highlights: • We use SUSY QM to obtain Hamiltonians with third-order differential ladder operators. • We show that these systems are related with the Painlevé IV equation. • We apply different definitions of coherent states to these Hamiltonians using the third-order ladder operators and some linearized ones. • We construct families of coherent states for such systems, which we called Painlevé IV coherent states

  12. 21 CFR 1308.14 - Schedule IV.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Schedule IV. 1308.14 Section 1308.14 Food and... isomers is possible: (1) Fenfluramine 1670 (e) Stimulants. Unless specifically excepted or unless listed... the following substances having a stimulant effect on the central nervous system, including its salts...

  13. Painlevé IV coherent states

    Energy Technology Data Exchange (ETDEWEB)

    Bermudez, David, E-mail: david.bermudez@weizmann.ac.il [Department of Physics of Complex Systems, Weizmann Institute of Science, Rehovot 76100 (Israel); Departamento de Física, Cinvestav, A.P. 14-740, 07000 México D.F. (Mexico); Contreras-Astorga, Alonso, E-mail: aloncont@iun.edu [Department of Mathematics and Actuarial Science, Indiana University Northwest, 3400 Broadway, Gary IN 46408 (United States); Departamento de Física, Cinvestav, A.P. 14-740, 07000 México D.F. (Mexico); Fernández C, David J., E-mail: david@fis.cinvestav.mx [Departamento de Física, Cinvestav, A.P. 14-740, 07000 México D.F. (Mexico)

    2014-11-15

    A simple way to find solutions of the Painlevé IV equation is by identifying Hamiltonian systems with third-order differential ladder operators. Some of these systems can be obtained by applying supersymmetric quantum mechanics (SUSY QM) to the harmonic oscillator. In this work, we will construct families of coherent states for such subset of SUSY partner Hamiltonians which are connected with the Painlevé IV equation. First, these coherent states are built up as eigenstates of the annihilation operator, then as displaced versions of the extremal states, both involving the related third-order ladder operators, and finally as extremal states which are also displaced but now using the so called linearized ladder operators. To each SUSY partner Hamiltonian corresponds two families of coherent states: one inside the infinite subspace associated with the isospectral part of the spectrum and another one in the finite subspace generated by the states created through the SUSY technique. - Highlights: • We use SUSY QM to obtain Hamiltonians with third-order differential ladder operators. • We show that these systems are related with the Painlevé IV equation. • We apply different definitions of coherent states to these Hamiltonians using the third-order ladder operators and some linearized ones. • We construct families of coherent states for such systems, which we called Painlevé IV coherent states.

  14. Scylla IV-P theta pinch

    International Nuclear Information System (INIS)

    Bailey, A.G.; Chandler, G.I.; Ekdahl, C.A. Jr.; Lillberg, J.W.; Machalek, M.D.; Seibel, F.T.

    1976-01-01

    Scylla IV-P is a flexible, linear theta pinch designed to investigate high-density linear concepts, end-stoppering, alternate heating methods, and plasma injection techniques relevant to a pure fusion reactor and/or a fusion-fission hybrid system. The construction and experimental arrangement of the device are briefly described

  15. The Contribution of IVS to IGGOS

    Science.gov (United States)

    Nothnagel, A.

    2002-05-01

    Since its inauguration in 1999, the International VLBI Service for Geodesy and Astrometry has made significant progress in the coordination and utilisation of worldwide VLBI resources. Improving the visibility of the IVS components to a wider public in turn led to a higher motivation of the individuals to contribute to the global effort. Not only the number of IVS components but also their investments in terms of funds and manpower demonstrate the increased awareness of the importance of this joint international endeavour. The different demands of the users but also of the contributors often require the definition of priorities which are only being acceptable due to the existence of a strong umbrella organisation like the IVS. Significant progress has also been made in the area of routine data analysis and combination of results. By now, six IVS Analysis Centers provide the redundancy necessary for a robust combination of the results. The use of ITRF2000 station coordinates as the basis for the IVS combined EOP series is the most recent step towards the generation of a consistent chain from the quasi-inertial frame of radio sources to system Earth.

  16. Distribution and identification of Plutonium(IV) species in tri-n-butyl phosphate/HNO3 extraction system containing acetohydroxamic acid

    International Nuclear Information System (INIS)

    Tkac, P.; Paulenova, A.; Vandegrift, G.F.; Krebs, J.F.

    2009-01-01

    There was a significant research progress achieved with the aim to modify conventional PUREX process by stripping of plutonium from the tri-n-butyl phosphate (TBP) extraction product in the form of non-extractable complexes upon addition of back-hold complexation agents. The present paper reports effects of such salt-free complexant, acetohydroxamic acid (HAHA), on distribution ratio of Pu(IV) under wide concentration of nitric acid and additional nitrate. General formula of plutonium species present in the organic phase can be described as Pu(OH) x (AHA) y (NO3) 4-x-y x 2TBP x wHNO 3 . (author)

  17. Congenital bilateral neuroblastoma (stage IV-S): case report

    International Nuclear Information System (INIS)

    Lee, Jeong Hee; Lee, Hee Jung; Woo, Seong Ku; Lee, Sang Rak; Kim, Heung Sik

    2002-01-01

    Congenital neonatal neuroblastoma is not uncommon but bilateral adrenal neuroblastoma is rare, accounting for about ten percent of neuroblastomas in children. We report the US the MR findings of a stage IV-S congenital bilateral neuroblastoma occurring in a one-day-old neonate

  18. Generation IV reactors: international projects

    International Nuclear Information System (INIS)

    Carre, F.; Fiorini, G.L.; Kupitz, J.; Depisch, F.; Hittner, D.

    2003-01-01

    Generation IV international forum (GIF) was initiated in 2000 by DOE (American department of energy) in order to promote nuclear energy in a long term view (2030). GIF has selected 6 concepts of reactors: 1) VHTR (very high temperature reactor system, 2) GHR (gas-cooled fast reactor system), 3) SFR (sodium-cooled fast reactor system, 4) SCWR (super-critical water-cooled reactor system), 5) LFR (lead-cooled fast reactor system), and 6) MFR (molten-salt reactor system). All these 6 reactor systems have been selected on criteria based on: - a better contribution to sustainable development (through their aptitude to produce hydrogen or other clean fuels, or to have a high energy conversion ratio...) - economic profitability, - safety and reliability, and - proliferation resistance. The 6 concepts of reactors are examined in the first article, the second article presents an overview of the results of the international project on innovative nuclear reactors and fuel cycles (INPRO) within IAEA. The project finished its first phase, called phase-IA. It has produced an outlook into the future role of nuclear energy and defined the need for innovation. The third article is dedicated to 2 international cooperations: MICANET and HTR-TN. The purpose of MICANET is to propose to the European Commission a research and development strategy in order to develop the assets of nuclear energy for the future. Future reactors are expected to be more multiple-purposes, more adaptable, safer than today, all these developments require funded and coordinated research programs. The aim of HTR-TN cooperation is to promote high temperature reactor systems, to develop them in a long term perspective and to define their limits in terms of burn-up and operating temperature. (A.C.)

  19. Glycogen Storage Disease Type IV

    DEFF Research Database (Denmark)

    Bendroth-Asmussen, Lisa; Aksglaede, Lise; Gernow, Anne B

    2016-01-01

    molecular genetic analyses confirmed glycogen storage disease Type IV with the finding of compound heterozygosity for 2 mutations (c.691+2T>C and c.1570C>T, p.R524X) in the GBE1 gene. We conclude that glycogen storage disease Type IV can cause early miscarriage and that diagnosis can initially be made...

  20. About the structure and stability of complex carbonates of thorium (IV), cerium (IV), zirconium (IV), hafnium (IV)

    International Nuclear Information System (INIS)

    Dervin, Jacqueline

    1972-01-01

    This research thesis addressed the study of complex carbonates of cations of metals belonging to the IV A column, i.e. thorium (IV), zirconium (IV), hafnium (IV), and also cerium (IV) and uranium (VI), and more particularly focused on ionic compounds formed in solution, and also on the influence of concentration and nature of cations on stability and nature of the formed solid. The author first presents methods used in this study, discusses their precision and scope of validity. She reports the study of the formation of different complex ions which have been highlighted in solution, and the determination of their formation constants. She reports the preparation and study of the stability domain of solid complexes. The next part reports the use of thermogravimetric analysis, IR spectrometry, and crystallography for the structural study of these compounds

  1. Industrial Waste Landfill IV upgrade package

    International Nuclear Information System (INIS)

    1994-01-01

    The Y-12 Plant, K-25 Site, and ORNL are managed by DOE's Operating Contractor (OC), Martin Marietta Energy Systems, Inc. (Energy Systems) for DOE. Operation associated with the facilities by the Operating Contractor and subcontractors, DOE contractors and the DOE Federal Building result in the generation of industrial solid wastes as well as construction/demolition wastes. Due to the waste streams mentioned, the Y-12 Industrial Waste Landfill IV (IWLF-IV) was developed for the disposal of solid industrial waste in accordance to Rule 1200-1-7, Regulations Governing Solid Waste Processing and Disposal in Tennessee. This revised operating document is a part of a request for modification to the existing Y-12 IWLF-IV to comply with revised regulation (Rule Chapters 1200-1-7-.01 through 1200-1-7-.08) in order to provide future disposal space for the ORR, Subcontractors, and the DOE Federal Building. This revised operating manual also reflects approved modifications that have been made over the years since the original landfill permit approval. The drawings referred to in this manual are included in Drawings section of the package. IWLF-IV is a Tennessee Department of Environmental and Conservation/Division of Solid Waste Management (TDEC/DSWM) Class 11 disposal unit

  2. IVS: Current Status and Future Plans

    Science.gov (United States)

    Behrend, D.; Nothnagel, A.; Petrachenko, W. T.; Tuccari, G.

    2016-12-01

    The International VLBI Service for Geodesy and Astrometry (IVS) is a globally operating service that coordinates and performs Very Long Baseline Interferometry (VLBI) activities through its constituent components. The VLBI activities are associated with the creation, provision, dissemination, and archiving of relevant VLBI data and products. The products mostly pertain to the determination of the celestial and terrestrial reference frames, the Earth orientation parameters (EOP), atmospheric parameters as well as other ancillary parameters. The IVS observational network currently consists of about 40 radio telescopes worldwide. Subsets of these telescopes (8-12 stations) participate in 24-hour observing sessions that are run several times per week and in 1-hour intensive sessions for UT1 determination every day. The current VLBI network was developed mainly in the 1970s and 1980s. A number of factors, including aging infrastructure and demanding new scientific requirements, started to challenge its future sustainability and relevance. In response, the IVS and other groups developed and started implementing the next generation VLBI system, called VGOS (VLBI Global Observing System), at existing and new sites. The VGOS network is expected to reach maturity in the early 2020s. We describe the current status, progress, and anticipated prospects of geodetic/astrometric VLBI and the IVS.

  3. Some features of formation and dissolution of a series of Pu(IV) and Zr alkyl and butyl alkyl phosphates in the system TBP -n-dodecane - nitric acid - water

    International Nuclear Information System (INIS)

    Markov, G.S.; Moshkov, M.M.; Kokina, S.A.

    1990-01-01

    The formation and composition of salts produced on interaction of a series of alkyl- and butylalkylphosphoric acids having alkyl radical chain lengths from C 4 to C 1 0 with Pu(IV) and Zr in organic and aqueous phases of the system TBP - n-dodecane -nitric acid - water were studied. The composition of compounds was found to depend on the conditions of their formation, defined first of all by the HNO 3 concentration in aqueous and organic phases. (author) 12 refs.; 4 figs.; 1 tab

  4. Gen IV Materials Handbook Implementation Plan

    International Nuclear Information System (INIS)

    Rittenhouse, P.; Ren, W.

    2005-01-01

    A Gen IV Materials Handbook is being developed to provide an authoritative single source of highly qualified structural materials information and materials properties data for use in design and analyses of all Generation IV Reactor Systems. The Handbook will be responsive to the needs expressed by all of the principal government, national laboratory, and private company stakeholders of Gen IV Reactor Systems. The Gen IV Materials Handbook Implementation Plan provided here addresses the purpose, rationale, attributes, and benefits of the Handbook and will detail its content, format, quality assurance, applicability, and access. Structural materials, both metallic and ceramic, for all Gen IV reactor types currently supported by the Department of Energy (DOE) will be included in the Gen IV Materials Handbook. However, initial emphasis will be on materials for the Very High Temperature Reactor (VHTR). Descriptive information (e.g., chemical composition and applicable technical specifications and codes) will be provided for each material along with an extensive presentation of mechanical and physical property data including consideration of temperature, irradiation, environment, etc. effects on properties. Access to the Gen IV Materials Handbook will be internet-based with appropriate levels of control. Information and data in the Handbook will be configured to allow search by material classes, specific materials, specific information or property class, specific property, data parameters, and individual data points identified with materials parameters, test conditions, and data source. Details on all of these as well as proposed applicability and consideration of data quality classes are provided in the Implementation Plan. Website development for the Handbook is divided into six phases including (1) detailed product analysis and specification, (2) simulation and design, (3) implementation and testing, (4) product release, (5) project/product evaluation, and (6) product

  5. Transcriptional regulator GntR of Brucella abortus regulates cytotoxicity, induces the secretion of inflammatory cytokines and affects expression of the type IV secretion system and quorum sensing system in macrophages.

    Science.gov (United States)

    Li, Zhiqiang; Wang, Shuli; Zhang, Hui; Zhang, Jinliang; Xi, Li; Zhang, Junbo; Chen, Chuangfu

    2017-03-01

    The pathogenic mechanisms of Brucella are still poorly understood. GntR is a transcriptional regulator and plays an important role in the intracellular survival of Brucella. To investigate whether GntR is involved in the cytotoxicity of Brucella abortus (B. abortus), we created a 2308ΔgntR mutant of B. abortus 2308 (S2308). Lactate dehydrogenase (LDH) cytotoxicity assays using a murine macrophage cell line (RAW 264.7) show that high-dose infection with the parental strain produces a high level of cytotoxicity to macrophages, but the 2308ΔgntR mutant exhibits a very low level of cytotoxicity, indicating that mutation of GntR impairs the cytotoxicity of B. abortus to macrophages. After the macrophages are infected with 2308ΔgntR, the levels of tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6) and interleukin-8 (IL-8) increase and are slightly higher than that for the S2308 infected group, indicating that the 2308ΔgntR mutant could induce the secretion of inflammatory cytokines. The virulence factor detection experiments indicate that genes involved in the type IV secretion system (T4SS) and quorum sensing system (QSS) are down-regulated in 2308ΔgntR. The lower levels of survival of 2308ΔgntR under various stress conditions and the increased sensitivity of 2308ΔgntR to polymyxin B suggest that GntR is a virulence factor and that deletion of gntR reduces of B. abortus to stress conditions. Taken together, our results demonstrate that GntR is involved in the cytotoxicity, virulence and intracellular survival of B. abortus during its infection.

  6. Extraction of Eu(III) and Th(IV) with TBP in n-dodecane in the presence of nitric acid and the thermodynamic activity of the TBP in the system

    International Nuclear Information System (INIS)

    Santos, F.S.M. dos.

    1983-02-01

    A qualitative description of the behavior of distribution coefficients of nitric acid, Th(IV) and Eu(III) separately in the system HNO 3 -H 2 O-TBP-n-dodecane and the effect of the temperature in the distribution coefficient of Th(IV) are presented. The distribution coefficient of Eu(III) between aqueous solutions nitric acid and solutions of TBP in n-dodecane are measured. Since the composition of the extracted Eu(III) complex is known, the theoretical course of the dependency of the distribution coefficient on the TBP concentration can be predicted. Deviations of experimental dependencies from theoretical ones give them information about the thermodynamic activity of TBP in the organic phase. A mathematical description for the distribution coefficients of Eu(III) and HNO 3 in the mentioned system was sugested. This description will make possible an avaliation of the behavior of the activity coefficients of TBP in the organic phase. (A.R.H.) [pt

  7. ASN’s actions in GEN IV reactors and Sodium Fast Reactors (SFR)

    International Nuclear Information System (INIS)

    Belot, Clotilde

    2013-01-01

    The ASN is involved in 3 actions concerning GEN IV: • Overview of nuclear reactor GEN IV systems; • Specific analysis about transmutation; • Prototype reactor ASTRID (SFR). Furthermore theses actions are in the beginning (no conclusions or results available)

  8. Direct Bandgap Group IV Materials

    Science.gov (United States)

    2016-01-21

    AFRL-AFOSR-JP-TR-2017-0049 Direct Bandgap group IV Materials Hung Hsiang Cheng NATIONAL TAIWAN UNIVERSITY Final Report 01/21/2016 DISTRIBUTION A...NAME(S) AND ADDRESS(ES) NATIONAL TAIWAN UNIVERSITY 1 ROOSEVELT RD. SEC. 4 TAIPEI CITY, 10617 TW 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING...14. ABSTRACT Direct bandgap group IV materials have been long sought for in both academia and industry for the implementation of photonic devices

  9. Systems Thinking for Strategic Leaders

    Science.gov (United States)

    2009-06-01

    needed to man weapons systems and equipment to fight according to Army doctrine. There are series of interactions that have second and third order...otherwise go. The indirect approach to diplomacy is especially difficult for democracies because the approach may appear to be leading the state in a...military operations must be approached from a systems perspective. In the ancient world, Xenophon, a contemporary of Plato , described just such a

  10. Sandia Pulse Reactor-IV Project

    International Nuclear Information System (INIS)

    Reuscher, J.A.

    1983-01-01

    Sandia National Laboratories has developed, designed and operated fast burst reactors for over 20 years. These reactors have been used for a variety of radiation effects programs. During this period, programs have required larger irradiation volumes primarily to expose complex electronic systems to postulated threat environments. As experiment volumes increased, a new reactor was built so that these components could be tested. The Sandia Pulse Reactor-IV is a logical evolution of the two decades of fast burst reactor development at Sandia

  11. Hope for progress after 40 years of futility? Novel approaches in the treatment of advanced stage III and IV non-small-cell-lung cancer: Stereotactic body radiation therapy, mediastinal lymphadenectomy, and novel systemic therapy

    Directory of Open Access Journals (Sweden)

    Simon Fung Kee Fung

    2012-01-01

    Full Text Available Non-small-cell lung cancer (NSCLC remains a leading cause of cancer mortality. The majority of patients present with advanced (stage III-IV disease. Such patients are treated with a variety of therapies including surgery, radiation, and chemotherapy. Despite decades of work, however, overall survival in this group has been resistant to any substantial improvement. This review briefly details the evolution to the current standard of care for advanced NSCLC, advances in systemic therapy, and novel techniques (stereotactic body radiation therapy [SBRT], and transcervical extended mediastinal lymphadenectomy [TEMLA] or video-assisted mediastinal lymphadenectomy [VAMLA] that have been used in localized NSCLC. The utility of these techniques in advanced stage therapy and potential methods of combining these novel techniques with systemic therapy to improve survival are discussed.

  12. Generation IV reactors: economics

    International Nuclear Information System (INIS)

    Dupraz, B.; Bertel, E.

    2003-01-01

    The operating nuclear reactors were built over a short period: no more than 10 years and today their average age rounds 18 years. EDF (French electricity company) plans to renew its reactor park over a far longer period : 30 years from 2020 to 2050. According to EDF this objective implies 3 constraints: 1) a service life of 50 to 60 years for a significant part of the present operating reactors, 2) to be ready to built a generation 3+ unit in 2020 which infers the third constraint: 3) to launch the construction of an EPR (European pressurized reactor) prototype as soon as possible in order to have it operating in 2010. In this scheme, generation 4 reactor will benefit the feedback experience of generation 3 and will take over in 2030. Economic analysis is an important tool that has been used by the generation 4 international forum to select the likely future reactor systems. This analysis is based on 4 independent criteria: the basic construction cost, the construction time, the operation and maintenance costs and the fuel cycle cost. This analysis leads to the evaluation of the global cost of electricity generation and of the total investment required for each of the reactor system. The former defines the economic competitiveness in a de-regulated energy market while the latter is linked to the financial risk taken by the investor. It appears, within the limits of the assumptions and models used, that generation 4 reactors will be characterized by a better competitiveness and an equivalent financial risk when compared with the previous generation. (A.C.)

  13. Impact and appreciation of two methods aiming at reducing hazardous drug environmental contamination: The centralization of the priming of IV tubing in the pharmacy and use of a closed-system transfer device.

    Science.gov (United States)

    Guillemette, Annie; Langlois, Hélène; Voisine, Maxime; Merger, Delphine; Therrien, Roxane; Mercier, Genevieve; Lebel, Denis; Bussières, Jean-François

    2014-12-01

    The main objective was to evaluate the impact of two methods aiming at reducing hazardous drug environmental contamination: the centralization of the priming of IV tubing in the pharmacy and the use of a closed-system transfer device. The secondary objective was to evaluate the satisfaction of pharmacy technicians using a survey. Sites in the hematology-oncology satellite pharmacy and care unit were analyzed for the presence of cyclophosphamide, ifosfamide and methotrexate before and after the centralization of the priming of IV tubing in the pharmacy and before and after using a closed-system transfer device. The limits of detection for cyclophosphamide, ifosfamide and methotrexate were, respectively, of 0.0015 ng/cm(2), 0.0012 ng/cm(2) and 0.0060 ng/cm(2). The pharmacy technician satisfaction was evaluated using a questionnaire. A total of 225 samples was quantified. After the centralization of priming in the pharmacy, no significant difference was found in the proportion of positive samples for cyclophosphamide, ifosfamide and methotrexate. Traces of cyclophosphamide found on the floor in patient care areas was significantly reduced (median[min-max] 0.08[0.06-0.09]ng/cm(2) vs. 0.03[0.02-0.05], p tubing in the pharmacy reduced floor contamination in patient care areas without increasing surface contamination in the pharmacy. Closed-system transfer devices reduced contamination in pharmacy, but handling issues were raised by pharmacy technicians. © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

  14. 78 FR 69434 - Post-Summary Corrections to Entry Summaries Filed in ACE Pursuant to the ESAR IV Test...

    Science.gov (United States)

    2013-11-19

    ... the testing of National Customs Automation Program (NCAP) components. A chronological listing of... conduct a NCAP test concerning new ACE ESAR IV capabilities (``ESAR IV test''). The ESAR IV test permitted... IV) Capabilities: 76 FR 37136 (June 24, 2011). NCAP Test Concerning the Document Imaging System: 77...

  15. Validation of SCALE 4.0 -- CSAS25 module and the 27-group ENDF/B-IV cross-section library for low-enriched uranium systems

    Energy Technology Data Exchange (ETDEWEB)

    Jordan, W.C.

    1993-02-01

    A version of KENO V.a and the 27-group library in SCALE-4.0 were validated for use in evaluating the nuclear criticality safety of low-enriched uranium systems. A total of 59 critical systems were analyzed. A statistical analysis of the results was performed, and subcritical acceptanced criteria are established.

  16. Validation of SCALE 4. 0 -- CSAS25 module and the 27-group ENDF/B-IV cross-section library for low-enriched uranium systems

    Energy Technology Data Exchange (ETDEWEB)

    Jordan, W.C.

    1993-02-01

    A version of KENO V.a and the 27-group library in SCALE-4.0 were validated for use in evaluating the nuclear criticality safety of low-enriched uranium systems. A total of 59 critical systems were analyzed. A statistical analysis of the results was performed, and subcritical acceptanced criteria are established.

  17. Free-format RPG IV

    CERN Document Server

    Martin, Jim

    2013-01-01

    This how-to guide offers a concise and thorough introduction to the increased productivity, better readability, and easier program maintenance that comes with the free-format style of programming in RPG IV. Although free-format information is available in IBM manuals, it is not separated from everything else, thereby requiring hours of tedious research to track down the information needed. This book provides everything one needs to know to write RPG IV in the free-format style, and author Jim Martin not only teaches rules and syntax but also explains how this new style of coding has the pot

  18. 12 CFR Appendix IV to Part 27 - Home Loan Data Submission

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Home Loan Data Submission IV Appendix IV to Part 27 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY FAIR HOUSING HOME LOAN DATA SYSTEM Pt. 27, App. IV Appendix IV to Part 27—Home Loan Data Submission ER21JN94.003 ER21JN94...

  19. 11. IV avati Draakoni galeriis...

    Index Scriptorium Estoniae

    2005-01-01

    Tanel Saare (sünd. 1979) näitus "Gott und huhn episode IV: seed shower". Eksponeeritakse väljavõtteid aktsioonidest aastatel 2000-2004 Turus, Nürnbergis, Berliinis, Lohusalus ja Soulis. Osa aktsioone toimus koos rühmitusega Non Grata

  20. The BANANA Project. IV. Two Aligned Stellar Rotation Axes in the Young Eccentric Binary System EP Crucis: Primordial Orientation and Tidal Alignment

    Science.gov (United States)

    Albrecht, Simon; Setiawan, Johny; Torres, Guillermo; Fabrycky, Daniel C.; Winn, Joshua N.

    2013-04-01

    With observations of the EP Cru system, we continue our series of measurements of spin-orbit angles in eclipsing binary star systems, the BANANA project (Binaries Are Not Always Neatly Aligned). We find a close alignment between the sky projections of the rotational and orbital angular momentum vectors for both stars (βp = -1.°8 ± 1.°6 and |βs| < 17°). We also derive precise absolute dimensions and stellar ages for this system. The EP Cru and DI Her systems provide an interesting comparison: they have similar stellar types and orbital properties, but DI Her is younger and has major spin-orbit misalignments, raising the question of whether EP Cru also had a large misalignment at an earlier phase of evolution. We show that tidal dissipation is an unlikely explanation for the good alignment observed today, because realignment happens on the same timescale as spin-orbit synchronization, and the stars in EP Cru are far from synchronization (they are spinning nine times too quickly). Therefore it seems that some binaries form with aligned axes, while other superficially similar binaries are formed with misaligned axes. Based on observations made with ESOs 2.2 m Telescopes at the La Silla Paranal Observatory under program ID 084.C-1008 (12.5%) and under MPIA guaranteed time (87.5%).

  1. A Study of Job Demands and Curriculum Development in Agricultural Training Related to the Muskegon County Wastewater Management System. Final Report. Volume IV. Career Awareness Information.

    Science.gov (United States)

    Fisher, Harold S.; And Others

    This is the final volume of a four-volume report of a research project designed to (1) identify job needs for agricultural occupations which will result from the Muskegon County Wastewater Management System and perform a task analysis on each occupation, (2) develop instructional modules and determine their place in either high school or 2-year…

  2. Energy-constrained open-system magmatic processes IV: Geochemical, thermal and mass consequences of energy-constrained recharge, assimilation and fractional crystallization (EC-RAFC)

    International Nuclear Information System (INIS)

    Wendy A. Bohrson Department of Geological Sciences, Central Washington University, Ellensburg, Washington, 98926, USA; Frank J. Spera Institute for Crustal Studies and Department of Geological Sciences, University of California, Santa Barbara, California, 93106, USA

    2003-01-01

    A wealth of geochemical and petrological data provide evidence that the processes of fractional crystallization, assimilation, and magma recharge (replenishment) dominate the chemical signatures of many terrestrial igneous rocks. Previous work [Spera and Bohrson, 2001 ; Bohrson and Spera, 2001] has established the importance of integrating energy, species and mass conservation into simulations of complex magma chamber processes. An extended version of the energy-constrained formulation, Energy-Constrained Recharge, Assimilation, Fractional Crystallization (EC-RAFC), tracks mass and compositional variations of melt, cumulates, and enclaves in a magma body undergoing simultaneous recharge, assimilation, and fractional crystallization [Spera and Bohrson, 2002]. Because many EC-RAFC results are distinct from those predicted by extant RAFC formulations, the primary goal of this paper is to present a range of geochemical and mass relationships for selected cases that highlight issues relevant to modern petrology. Among the plethora of petrologic problems that have important, well-documented analogues in nature are the geochemical distinctions that arise when a magma body undergoes continuous versus episodic recharge, the connection between erupted magmas and associated cumulate bodies, the behavior of recharge-fractionation dominated systems (RFC), thermodynamic conditions that promote the formation of enclaves versus cumulates, and the conditions under which magma bodies may be described as chemically homogeneous. Investigation of the effects of continuous versus episodic recharge for mafic magma undergoing RAFC in the lower crust indicates that the resulting geochemical trends for melt and solids are sensitive to the intensity and composition of recharge, suggesting that EC-RAFC may be used as a tool to distinguish the nature of the recharge events. Compared to the record preserved in melts, the geochemical and mass characteristics of solids associated with particular

  3. Generation IV nuclear energy systems: road map and concepts. 3. Measurement and Analysis of Conducted Noise at Main Control Room in Uljin NPP

    International Nuclear Information System (INIS)

    Goo, Cheol-Soo; Kim, Bok-Ryul; Cho, Won-Seo

    2001-01-01

    The utility has implemented digital technology into the design of the plant protection system in new nuclear power plants (NPPs) and also replaced existing analog instrumentation and control (I and C) systems with computer-based digital I and C systems as the analog systems become obsolete. Digital I and C systems, which provide more operating capabilities than analog systems, operate at conditions that are more vulnerable to EMI/RFI than existing analog systems. The purpose of the site survey is to get the actual electromagnetic measurement (EM) level in NPPs and to eliminate the need for plant-specific EM at the point of installation to demonstrate the sufficiency of equipment test levels. Actual electromagnetic environments in NPPs are major elements to decide the limit for the susceptibility of the installed equipment. The data obtained with standard methods are indispensable to make guidelines for an electromagnetic qualification test for the equipment to be installed in the NPP. We performed EM at the power ports of the Plant Control System (PCS) and the Core Protection Calculator (CPC) in Uljin to obtain the conducted noise level, which can be utilized to determine the electromagnetic environment test limit for the equipment qualification test. The continuous conducted noise and discontinuous transient or surge at the power ports of the PCS and the CPC installed at the no.3 main control room in the Uljin NPP were measured and analyzed. The measurements were continuously conducted for 2 weeks of the power-escalated phase with reactor power from 0% to full power. The measurements selected for the power leaders were the current and voltage of the power cables using a current and voltage (passive) probe, EMI test receiver, and notebook computer. The data were recorded in accordance with standard industry practices and procedures. The conducted noise current was measured over the frequency range of 30 Hz to 50 kHz, and the voltage was captured over the frequency

  4. Revised and extended analysis of Br IV

    International Nuclear Information System (INIS)

    Riyaz, A.; Rahimullah, K.; Tauheed, A.

    2014-01-01

    The spectrum of three-times ionized bromine Br IV has been studied in the 319–2350 Å wavelength region. The spectrum was recorded on a 3-m normal incidence vacuum spectrograph at the St. Francis Xavier University, Antigonish (Canada) and 6.65-m grazing incidence spectrograph at the Zeeman laboratory (Amsterdam). The light sources used were a triggered spark and sliding spark, respectively. The ground configuration of Br IV 3d 10 4s 2 4p 2 , the excited configurations 3d 10 4s4p 3 +3d 10 4s 2 4p (4d+5d+6d+5s+6s+7s) in the odd parity system and 3d 10 4s 2 4p (5p+4f+5f)+3d 10 4s4p 2 (4d+5s)+3d 10 4p 4 in the even parity system have been studied. Relativistic Hartree–Fock (HFR) and least squares fitted (LSF) parametric calculations were used to interpret the observed spectrum. 120 Levels of Br IV have now been established, 58 being new. Among 424 spectral lines, 277 are newly classified. The levels 4s4p 35 S 2 , 4s 2 4p4d 3 F 4 and 4p5p ( 3 P 0,1 , 3 D 1,2 , 3 S 1 ) are revised. We estimate the accuracy of our measured wavelength for sharp and unblended lines to be ±0.005 Å. The ionization limit is determined as 385,390±100 cm −1 (47.782±0.012 eV). -- Highlights: • The spectrum of Br was recorded on a 3-m spectrograph with triggered spark source. • Atomic transitions for Br IV were identified to established new energy levels. • CI calculations with relativistic corrections were made for theoretical predictions. • Weighted oscillator strength (gf) and transition probabilities (gA) were calculated. • Ionization potential of Br IV was determined experimentally

  5. Handling of computational in vitro/in vivo correlation problems by Microsoft Excel: IV. Generalized matrix analysis of linear compartment systems.

    Science.gov (United States)

    Langenbucher, Frieder

    2005-01-01

    A linear system comprising n compartments is completely defined by the rate constants between any of the compartments and the initial condition in which compartment(s) the drug is present at the beginning. The generalized solution is the time profiles of drug amount in each compartment, described by polyexponential equations. Based on standard matrix operations, an Excel worksheet computes the rate constants and the coefficients, finally the full time profiles for a specified range of time values.

  6. Sorption properties and reversibility of Ti(IV) and Nb(V)-fluoride doped-Ca(BH4)2-MgH2 system

    International Nuclear Information System (INIS)

    Bonatto Minella, Christian; Garroni, Sebastiano; Pistidda, Claudio; Baró, Maria Dolors; Gutfleisch, Oliver; Klassen, Thomas; Dornheim, Martin

    2015-01-01

    Highlights: • Faster desorption reaction for doped materials vs. the pure composite system. • Kinetic improvement concerning re-hydrogenation reaction showed by the addition of NbF 5 . • Full characterization of the de-hydrogenation reaction pathway by means of both SR-PXD and 11 B{ 1 H} MAS-NMR. • Study of the evolution of the chemical state of the additives upon both milling and sorption reactions. - Abstract: In the last decade, alkaline and alkaline earth metal tetrahydroborates have been the focuses of the research due to their high gravimetric and volumetric hydrogen densities. Among them, Ca(BH 4 ) 2 and the Ca(BH 4 ) 2 + MgH 2 reactive hydride composites (RHC), were calculated to have the ideal thermodynamic properties which fall within the optimal range for mobile applications. In this study, the addition of NbF 5 or TiF 4 to the Ca(BH 4 ) 2 + MgH 2 reactive hydride composite system was attempted aiming to obtain a full reversible system with the simultaneous suppression of CaB 12 H 12 . Structural characterization of the specimens was performed by means of in-situ Synchrotron Radiation Powder X-ray diffraction (SR-PXD) and 11 B{ 1 H} Solid State Magic Angle Spinning-Nuclear Magnetic Resonance (MAS-NMR). The evolution of the chemical state of the Nb- and Ti-based additives was monitored by X-ray Absorption Near Edge Structure (XANES). The addition of NbF 5 or TiF 4 to the Ca(BH 4 ) 2 + MgH 2 system have not suppressed completely the formation of CaB 12 H 12 and only a slight improvement concerning the reversible reaction was displayed just in the case of Nb-doped composite material

  7. Two-stage precipitation of neptunium (IV) oxalate

    International Nuclear Information System (INIS)

    Luerkens, D.W.

    1983-07-01

    Neptunium (IV) oxalate was precipitated using a two-stage precipitation system. A series of precipitation experiments was used to identify the significant process variables affecting precipitate characteristics. Process variables tested were input concentrations, solubility conditions in the first stage precipitator, precipitation temperatures, and residence time in the first stage precipitator. A procedure has been demonstrated that produces neptunium (IV) oxalate particles that filter well and readily calcine to the oxide

  8. Laparostomy management using the ABThera™ open abdomen negative pressure therapy system in a grade IV open abdomen secondary to acute pancreatitis.

    Science.gov (United States)

    Fitzgerald, James E F; Gupta, Shradha; Masterson, Sarah; Sigurdsson, Helgi H

    2013-04-01

    Wound control in laparostomy for the treatment of intra-abdominal hypertension remains challenging and numerous techniques have been described. We report the first UK experience with a new commercially available device specifically designed to facilitate management of the open abdomen. A 44-year-old gentleman presented with a 3-day history of constant severe epigastric pain and associated vomiting. Amylase was markedly elevated and he was admitted for supportive management of pancreatitis, with subsequent transfer to intensive care due to severe systemic inflammatory syndrome. The patient decompensated, developing intra-abdominal hypertension with renal and respiratory failure. This was successfully managed by performing a laparostomy and using an ABThera™ Open Abdomen Negative Pressure Therapy System (KCI, San Antonio, TX). We describe its use to facilitate wound control, including enteroatmospheric fistula, allowing granulation and eventual restoration of gastrointestinal continuity 383-days after admission. We found the ABThera™ System proved to be a useful treatment adjunct, protecting intra-abdominal contents while removing large volumes of exudate and infected material from within the abdominal cavity. Complex cases such as this remain infrequent and this article provides a summary of our experience, including a review of indications for laparostomy and the underlying basic science in this difficult area. © 2012 The Authors. International Wound Journal © 2012 Blackwell Publishing Ltd and Medicalhelplines.com Inc.

  9. THE HST/ACS COMA CLUSTER SURVEY. IV. INTERGALACTIC GLOBULAR CLUSTERS AND THE MASSIVE GLOBULAR CLUSTER SYSTEM AT THE CORE OF THE COMA GALAXY CLUSTER

    International Nuclear Information System (INIS)

    Peng, Eric W.; Ferguson, Henry C.; Goudfrooij, Paul; Hammer, Derek; Lucey, John R.; Marzke, Ronald O.; Puzia, Thomas H.; Carter, David; Balcells, Marc; Bridges, Terry; Chiboucas, Kristin; Del Burgo, Carlos; Graham, Alister W.; Guzman, Rafael; Hudson, Michael J.; Matkovic, Ana

    2011-01-01

    Intracluster stellar populations are a natural result of tidal interactions in galaxy clusters. Measuring these populations is difficult, but important for understanding the assembly of the most massive galaxies. The Coma cluster of galaxies is one of the nearest truly massive galaxy clusters and is host to a correspondingly large system of globular clusters (GCs). We use imaging from the HST/ACS Coma Cluster Survey to present the first definitive detection of a large population of intracluster GCs (IGCs) that fills the Coma cluster core and is not associated with individual galaxies. The GC surface density profile around the central massive elliptical galaxy, NGC 4874, is dominated at large radii by a population of IGCs that extend to the limit of our data (R +4000 -5000 (systematic) IGCs out to this radius, and that they make up ∼70% of the central GC system, making this the largest GC system in the nearby universe. Even including the GC systems of other cluster galaxies, the IGCs still make up ∼30%-45% of the GCs in the cluster core. Observational limits from previous studies of the intracluster light (ICL) suggest that the IGC population has a high specific frequency. If the IGC population has a specific frequency similar to high-S N dwarf galaxies, then the ICL has a mean surface brightness of μ V ∼ 27 mag arcsec -2 and a total stellar mass of roughly 10 12 M sun within the cluster core. The ICL makes up approximately half of the stellar luminosity and one-third of the stellar mass of the central (NGC 4874+ICL) system. The color distribution of the IGC population is bimodal, with blue, metal-poor GCs outnumbering red, metal-rich GCs by a ratio of 4:1. The inner GCs associated with NGC 4874 also have a bimodal distribution in color, but with a redder metal-poor population. The fraction of red IGCs (20%), and the red color of those GCs, implies that IGCs can originate from the halos of relatively massive, L* galaxies, and not solely from the disruption of

  10. Sorption properties and reversibility of Ti(IV) and Nb(V)-fluoride doped-Ca(BH{sub 4}){sub 2}-MgH{sub 2} system

    Energy Technology Data Exchange (ETDEWEB)

    Bonatto Minella, Christian, E-mail: christian.minella@kit.edu [Institute for Metallic Materials, IFW Dresden, Helmholtzstrasse 20, D-01069 Dresden (Germany); Technische Universität Dresden, D-01062 Dresden (Germany); Garroni, Sebastiano [Dipartimento di Chimica e Farmacia, Universitá di Sassari and INSTM, Via Vienna 2, I-07100 Sassari (Italy); Pistidda, Claudio [Institute of Materials Research, Materials Technology, Helmholtz-Zentrum Geesthacht, Zentrum für Material- und Küstenforschung GmbH, Max Planck Str. 1, D-21502 Geesthacht (Germany); Baró, Maria Dolors [Departament de Física, Universitat Autònoma de Barcelona, E-08193 Bellaterra (Spain); Gutfleisch, Oliver [Materials Science, Technische Universität Darmstadt, Alarich-Weiss-Str. 16, 64287 Darmstadt (Germany); Klassen, Thomas; Dornheim, Martin [Institute of Materials Research, Materials Technology, Helmholtz-Zentrum Geesthacht, Zentrum für Material- und Küstenforschung GmbH, Max Planck Str. 1, D-21502 Geesthacht (Germany)

    2015-02-15

    Highlights: • Faster desorption reaction for doped materials vs. the pure composite system. • Kinetic improvement concerning re-hydrogenation reaction showed by the addition of NbF{sub 5}. • Full characterization of the de-hydrogenation reaction pathway by means of both SR-PXD and {sup 11}B{"1H} MAS-NMR. • Study of the evolution of the chemical state of the additives upon both milling and sorption reactions. - Abstract: In the last decade, alkaline and alkaline earth metal tetrahydroborates have been the focuses of the research due to their high gravimetric and volumetric hydrogen densities. Among them, Ca(BH{sub 4}){sub 2} and the Ca(BH{sub 4}){sub 2} + MgH{sub 2} reactive hydride composites (RHC), were calculated to have the ideal thermodynamic properties which fall within the optimal range for mobile applications. In this study, the addition of NbF{sub 5} or TiF{sub 4} to the Ca(BH{sub 4}){sub 2} + MgH{sub 2} reactive hydride composite system was attempted aiming to obtain a full reversible system with the simultaneous suppression of CaB{sub 12}H{sub 12}. Structural characterization of the specimens was performed by means of in-situ Synchrotron Radiation Powder X-ray diffraction (SR-PXD) and {sup 11}B{"1H} Solid State Magic Angle Spinning-Nuclear Magnetic Resonance (MAS-NMR). The evolution of the chemical state of the Nb- and Ti-based additives was monitored by X-ray Absorption Near Edge Structure (XANES). The addition of NbF{sub 5} or TiF{sub 4} to the Ca(BH{sub 4}){sub 2} + MgH{sub 2} system have not suppressed completely the formation of CaB{sub 12}H{sub 12} and only a slight improvement concerning the reversible reaction was displayed just in the case of Nb-doped composite material.

  11. Microwave discharge electrodeless lamps (MDEL). Part IV. Novel self-ignition system incorporating metallic microwave condensing cones to activate MDELs in photochemical reactions.

    Science.gov (United States)

    Horikoshi, Satoshi; Tsuchida, Akihiro; Sakai, Hideki; Abe, Masahiko; Sato, Susumu; Serpone, Nick

    2009-11-01

    A metallic condensing cone that concentrates microwave radiation (equivalent to an optical lens) has been developed and used as part of a system to activate a microwave discharge electrodeless lamp (MDEL) in the oxidative treatment of wastewaters by aiding the novel self-ignition of the lamp on irradiation at low microwave power levels. This approach to self-ignition can potentially lead to considerable energy savings in such treatments. System performance was examined for the ignition power of microwaves of such MDEL devices in water, whose usefulness was assessed by investigating the photolytic transformation of aqueous solutions of representatives of three classes of contaminants: chlorinated phenols, herbicides and endocrine disruptors, specifically 4-chlorophenol (4-CP), 2,4-dichlorophenoxyacetic acid (2,4-D) and 4,4'-isopropylidenediphenol (bisphenol-A; BPA), respectively, taken as model wastewaters in air-equilibrated, in oxygen-saturated and in TiO2-containing aqueous media. The results are discussed in terms of the dynamics of the photo-induced degradation processes.

  12. The evolution of low-mass close binary systems. IV. 0.80 M/sub sun/+0.40 M/sub sun/: Catastrophic mass loss

    International Nuclear Information System (INIS)

    Webbink, R.F.

    1977-01-01

    The evolution of both components of a 0.80 M/sub sun/+0.40 M/sub sun/ binary with initial separation 1.60 R/sub sun/ is presented. This system reaches mass transfer during core hydrogen burning in the primary. The primary has such a deep convective envelope that mass transfer proceeds on a dynamical time scale. Mass exchange is followed through the first 6.25 x 10 -3 M/sub sun/, by which time the transfer rate has reached 8.33 x 10 -4 M/sub sun/ yr -1 .It is shown that mass transfer on a dynamical time scale leads to supercritical accretion by the secondary component, and hence is presumably accompanied by extensive mass and angular momentum losses. Stability against such rapid mass transfer may impose severe limitations on the masses and mass ratios of cataclysmic variables

  13. Uruguay; 2011 Article IV Consultation

    OpenAIRE

    International Monetary Fund

    2011-01-01

    This 2011 Article IV Consultation highlights that the growth momentum in Uruguay has continued into 2011 but a slowdown is under way, led by weaker exports and slower public investment. Uruguay’s economic and financial vulnerabilities are modest, and the government has reduced debt vulnerabilities significantly and built important financial buffers. Executive Directors have commended authorities’ skillful macroeconomic management that has underpinned Uruguay’s excellent economic performance, ...

  14. Congestion based mechanism for route discovery in a V2I-V2V system applying smart devices and IoT.

    Science.gov (United States)

    Parrado, Natalia; Donoso, Yezid

    2015-03-31

    The Internet of Things is a new paradigm in which objects in a specific context can be integrated into traditional communication networks to actively participate in solving a determined problem. The Vehicle-to-Vehicle (V2V) and Vehicle-to-Infrastructure (V2I) technologies are specific cases of IoT and key enablers for Intelligent Transportation Systems (ITS). V2V and V2I have been widely used to solve different problems associated with transportation in cities, in which the most important is traffic congestion. A high percentage of congestion is usually presented by the inappropriate use of resources in vehicular infrastructure. In addition, the integration of traffic congestion in decision making for vehicular traffic is a challenge due to its high dynamic behavior. In this paper, an optimization model over the load balancing in the congestion percentage of the streets is formulated. Later, we explore a fully congestion-oriented route discovery mechanism and we make a proposal on the communication infrastructure that should support it based on V2I and V2V communication. The mechanism is also compared with a modified Dijkstra's approach that reacts at congestion states. Finally, we compare the results of the efficiency of the vehicle's trip with the efficiency in the use of the capacity of the vehicular network.

  15. Congestion Based Mechanism for Route Discovery in a V2I-V2V System Applying Smart Devices and IoT

    Directory of Open Access Journals (Sweden)

    Natalia Parrado

    2015-03-01

    Full Text Available The Internet of Things is a new paradigm in which objects in a specific context can be integrated into traditional communication networks to actively participate in solving a determined problem. The Vehicle-to-Vehicle (V2V and Vehicle-to-Infrastructure (V2I technologies are specific cases of IoT and key enablers for Intelligent Transportation Systems (ITS. V2V and V2I have been widely used to solve different problems associated with transportation in cities, in which the most important is traffic congestion. A high percentage of congestion is usually presented by the inappropriate use of resources in vehicular infrastructure. In addition, the integration of traffic congestion in decision making for vehicular traffic is a challenge due to its high dynamic behavior. In this paper, an optimization model over the load balancing in the congestion percentage of the streets is formulated. Later, we explore a fully congestion-oriented route discovery mechanism and we make a proposal on the communication infrastructure that should support it based on V2I and V2V communication. The mechanism is also compared with a modified Dijkstra’s approach that reacts at congestion states. Finally, we compare the results of the efficiency of the vehicle’s trip with the efficiency in the use of the capacity of the vehicular network.

  16. U(IV) fluorescence spectroscopy. A new speciation tool

    Energy Technology Data Exchange (ETDEWEB)

    Lehmann, Susanne; Brendler, Vinzenz [Helmholtz-Zentrum Dresden-Rossendorf e.V., Dresden (Germany). Surface Processes; Steudtner, Robin [Helmholtz-Zentrum Dresden-Rossendorf e.V., Dresden (Germany). Inst. of Resource Ecology

    2017-06-01

    We combined absorption and fluorescence spectroscopy to study the speciation of U(IV) in solution in concentrations down to 10{sup -6} M uranium. With our time-resolved laser-induced fluorescence setup we could determine the fluorescence decay time of U(IV) in perchloric as well as in chloric acid with 2.6 ± 0.3 ns at room temperature and 148.4 ± 6.5 ns at liquid nitrogen temperature. For the U(IV) sulfate system, we observed a bathochromic shift and a peak shape modification in the fluorescence spectra with increasing sulfate concentration in solution. Thus, the potential of U(IV) fluorescence for speciation analysis could be proven.

  17. Revised and extended analysis of Br IV

    Science.gov (United States)

    Riyaz, A.; Rahimullah, K.; Tauheed, A.

    2014-01-01

    The spectrum of three-times ionized bromine Br IV has been studied in the 319-2350 Å wavelength region. The spectrum was recorded on a 3-m normal incidence vacuum spectrograph at the St. Francis Xavier University, Antigonish (Canada) and 6.65-m grazing incidence spectrograph at the Zeeman laboratory (Amsterdam). The light sources used were a triggered spark and sliding spark, respectively. The ground configuration of Br IV 3d104s24p2, the excited configurations 3d104s4p3+3d104s24p (4d+5d+6d+5s+6s+7s) in the odd parity system and 3d104s24p (5p+4f+5f)+3d104s4p2 (4d+5s)+3d104p4 in the even parity system have been studied. Relativistic Hartree-Fock (HFR) and least squares fitted (LSF) parametric calculations were used to interpret the observed spectrum. 120 Levels of Br IV have now been established, 58 being new. Among 424 spectral lines, 277 are newly classified. The levels 4s4p35S2, 4s24p4d 3F4 and 4p5p (3P0, 1, 3D1, 2, 3S1) are revised. We estimate the accuracy of our measured wavelength for sharp and unblended lines to be ±0.005 Å. The ionization limit is determined as 385,390±100 cm-1 (47.782±0.012 eV).

  18. AtlA Functions as a Peptidoglycan Lytic Transglycosylase in the Neisseria gonorrhoeae Type IV Secretion System▿

    OpenAIRE

    Kohler, Petra L.; Hamilton, Holly L.; Cloud-Hansen, Karen; Dillard, Joseph P.

    2007-01-01

    Type IV secretion systems require peptidoglycan lytic transglycosylases for efficient secretion, but the function of these enzymes is not clear. The type IV secretion system gene cluster of Neisseria gonorrhoeae encodes two peptidoglycan transglycosylase homologues. One, LtgX, is similar to peptidoglycan transglycosylases from other type IV secretion systems. The other, AtlA, is similar to endolysins from bacteriophages and is not similar to any described type IV secretion component. We chara...

  19. Nordic Nuclear Materials Forum for Generation IV Reactors

    International Nuclear Information System (INIS)

    Anghel, C.; Penttilae, S.

    2010-03-01

    A network for material issues for Generation IV nuclear power has been initiated within the Nordic countries. The objectives of the Generation IV Nordic Nuclear Materials Forum (NOMAGE4) are to put the basis of a sustainable forum for Gen IV issues, especially focussing on fuels, cladding, structural materials and coolant interaction. Other issues include reactor physics, dynamics and diagnostics, core and fuel design. The present report summarizes the work performed during the year 2009. The efforts made include identification of organisations involved in Gen IV issues in the Nordic countries, update of the forum website, http://www.studsvik.se/GenerationIV, and investigation of capabilities for research within the area of Gen IV. Within the NOMAGE4 project a seminar on Generation IV Nuclear Energy Systems has been organized during 15-16th of October 2009. The aim of the seminar was to provide a forum for exchange of information, discussion on future research needs and networking of experts on Generation IV reactor concepts. As an outcome of the NOMAGE4, a few collaboration project proposals have been prepared/planned in 2009. The network was welcomed by the European Commission and was mentioned as an exemplary network with representatives from industries, universities, power companies and research institutes. NOMAGE4 has been invited to participate to the 'European Energy Research Alliance, EERA, workshop for nuclear structural materials' http://www.eera-set.eu/index.php?index=41 as external observers. Future plans include a new Nordic application for continuation of NOMAGE4 network. (author)

  20. Nordic Nuclear Materials Forum for Generation IV Reactors

    Energy Technology Data Exchange (ETDEWEB)

    Anghel, C. (Studsvik Nuclear AB, Nykoeping (Sweden)); Penttilae, S. (Technical Research Centre of Finland, VTT (Finland))

    2010-03-15

    A network for material issues for Generation IV nuclear power has been initiated within the Nordic countries. The objectives of the Generation IV Nordic Nuclear Materials Forum (NOMAGE4) are to put the basis of a sustainable forum for Gen IV issues, especially focussing on fuels, cladding, structural materials and coolant interaction. Other issues include reactor physics, dynamics and diagnostics, core and fuel design. The present report summarizes the work performed during the year 2009. The efforts made include identification of organisations involved in Gen IV issues in the Nordic countries, update of the forum website, http://www.studsvik.se/GenerationIV, and investigation of capabilities for research within the area of Gen IV. Within the NOMAGE4 project a seminar on Generation IV Nuclear Energy Systems has been organized during 15-16th of October 2009. The aim of the seminar was to provide a forum for exchange of information, discussion on future research needs and networking of experts on Generation IV reactor concepts. As an outcome of the NOMAGE4, a few collaboration project proposals have been prepared/planned in 2009. The network was welcomed by the European Commission and was mentioned as an exemplary network with representatives from industries, universities, power companies and research institutes. NOMAGE4 has been invited to participate to the 'European Energy Research Alliance, EERA, workshop for nuclear structural materials' http://www.eera-set.eu/index.php?index=41 as external observers. Future plans include a new Nordic application for continuation of NOMAGE4 network. (author)

  1. Crystalline cerium(IV) phosphates

    International Nuclear Information System (INIS)

    Herman, R.G.; Clearfield, A.

    1976-01-01

    The ion exchange behaviour of seven crystalline cerium(IV) phosphates towards some of the alkali metal cations is described. Only two of the compounds (A and C) possess ion exchange properties in acidic solutions. Four others show some ion exchange characteristics in basic media with some of the alkali cations. Compound G does not behave as an ion exchanger in solutions of pH + , but show very little Na + uptake. Compound E undergoes ion exchange with Na + and Cs + , but not with Li+. Both Li + and Na + are sorbed by compounds A and C. The results are indicative of structures which show steric exclusion phenomena. (author)

  2. PREPARATION OF OXOPORPHINATOMANGANESE (IV) COMPLEX

    Energy Technology Data Exchange (ETDEWEB)

    Willner, I.; Otvos, J.; Calvin, M.

    1980-07-01

    Oxo-manganese-tetraphenylporphyrin (O=Mn{sup IV}-TPP) has been prepared by an oxygen-transfer reaction from iodosylbenzene to MnIITPP and characterized by its i.r. and field desorption mass spectra, which are identical to those of the product obtained by direct oxidation of Mn{sup III}(TPP) in an aqueous medium; it transfers oxygen to triphenylphosphine to produce triphenylphosphine oxide, and it is suggested that similar intermediates are important in oxygen activation by cytochrome P-450 as well as in the photosynthetic evolution of oxygen.

  3. KENO-IV code benchmark calculation, (6)

    International Nuclear Information System (INIS)

    Nomura, Yasushi; Naito, Yoshitaka; Yamakawa, Yasuhiro.

    1980-11-01

    A series of benchmark tests has been undertaken in JAERI in order to examine the capability of JAERI's criticality safety evaluation system consisting of the Monte Carlo calculation code KENO-IV and the newly developed multigroup constants library MGCL. The present report describes the results of a benchmark test using criticality experiments about Plutonium fuel in various shape. In all, 33 cases of experiments have been calculated for Pu(NO 3 ) 4 aqueous solution, Pu metal or PuO 2 -polystyrene compact in various shape (sphere, cylinder, rectangular parallelepiped). The effective multiplication factors calculated for the 33 cases distribute widely between 0.955 and 1.045 due to wide range of system variables. (author)

  4. Investigating the reasons of variability in Si IV and C IV broad absorption line troughs of quasars

    Science.gov (United States)

    Stathopoulos, Dimitrios; Lyratzi, Evangelia; Danezis, Emmanuel; Antoniou, Antonios; Tzimeas, Dimitrios

    2017-09-01

    In this paper we analyze the C IV and Si IV broad absorption troughs of two BALQSOs (J101056.69+355833.3, J114548.38+393746.6) to the individual components they consist of. By analyzing a BAL trough to its components we have the advantage to study the variations of the individual absorbing systems in the line of sight and not just the variations of the whole absorption trough or the variations of selected portions of BAL troughs exhibiting changes. We find that the velocity shifts and FWHMs (Full Width at Half Maximum) of the individual components do not vary between an interval of six years. All variable components show changes in the optical depths at line centers which are manifested as variations in the EW (Equivalent Width) of the components. In both BALQSOs, over corresponding velocities, Si IV has higher incidence of variability than C IV. From our analysis, evidence is in favour of different covering fractions between C IV and Si IV. Finally, although most of our results favour the crossing cloud scenario as the cause of variability, there is also strong piece of evidence indicating changing ionization as the source of variability. Thus, a mixed situation where both physical mechanisms contribute to BAL variability is the most possible scenario.

  5. Androgynes et gynandres : la relecture péladanienne du Banquet de Platon // Androgynes and gynandres : The Péladan’s reinterpretation of the Symposium by Plato

    OpenAIRE

    Eva Voldřichová Beránková

    2015-01-01

    The Symposium alias The Banquet belongs to those hypotexts by Plato which have been constantly reread and reinterpreted by the authors of French decadence. This article is focused on the Péladan’s reinterpretation of one of its parts, the famous Aristophanes’s speech about love. It implies on one hand the masculine notion of “androgyne”, heavily valorised in the fin de siècle novels, and, on the other hand, the feminine concept of “gynandre”, perceived negatively, feared and mocke...

  6. Test Review: Advanced Clinical Solutions for WAIS-IV and WMS-IV

    Science.gov (United States)

    Chu, Yiting; Lai, Mark H. C.; Xu, Yining; Zhou, Yuanyuan

    2012-01-01

    The authors review the "Advanced Clinical Solutions for WAIS-IV and WMS-IV". The "Advanced Clinical Solutions (ACS) for the Wechsler Adult Intelligence Scale-Fourth Edition" (WAIS-IV; Wechsler, 2008) and the "Wechsler Memory Scale-Fourth Edition" (WMS-IV; Wechsler, 2009) was published by Pearson in 2009. It is a…

  7. Some oxozirconium(IV) compounds

    Energy Technology Data Exchange (ETDEWEB)

    Paul, R C; Gupta, S K; Parmar, S S; Vasisht, S K [Punjab Univ., Chandigarh (India). Dept. of Chemistry

    1976-01-01

    Some new oxozirconium(IV) complexes, ZrO(An)/sub 2/, ZrO(Gly)/sub 2/, ZrO(HSal)/sub 2/, ZrO(HPth)/sub 2/, ZrO(Pic)/sub 2/(HPic)/sub 2/, and ZrO(Quin)/sub 2/(HQuin)/sub 2/ have been isolated from the reactions of ZrO(CH/sub 3/COO)/sub 2/CH/sub 3/COOH with anthranilic acid (HAn), glycine (HGly), salicylic acid (H/sub 2/Sal), phthalic acid (H/sub 2/Pth), picolinic acid (HPic), and 8-quinolinol (HQuin) respectively. Their important infrared bands and wherever possible molar conductance and molecular weight have been reported.

  8. US Nuclear Regulatory Commission region IV

    International Nuclear Information System (INIS)

    Vanderburch, C.

    1996-01-01

    The NRC has established a policy to provide for the timely through and systematic inspection of significant operational events at nuclear power plants. This includes the use of an Augmented Inspection Team to determine the causes, conditions, and circumstances relevant to an event and to communicate its findings and conclusions to NRC management. In accordance with NRC Inspection Manual Chapter 0325. The Region IV Regional Administrator dispatched an Augmented Inspection Team to the Wolf Creek Nuclear Generating Station to review the circumstances surrounding a manual reactor trip on January 30, 1996, with the failure of five control rods to fully insert into the core, a failure of the turbine-driven auxiliary feedwater pump, and the subsequent loss of one train of the essential service water system

  9. Phase Content and Equilibrium Relationships in Ternary Systems MOx/VO2,5/PO2,5 (M = TiIV, ZrIV, NbV; x = 2 or 2,5) with Additions for Four-Component System Ti/Cr/P/O

    International Nuclear Information System (INIS)

    Titlbach, Sven

    2014-01-01

    In the systems TiO 2 / V 2 O 5 / P 2 O 5 , ZrO 2 / V 2 O 5 / P 2 O 5 and Nb 2 O 5 / V 2 O 5 / P 2 O 5 studies on phase composition and the equilibrium relations were performed in the context of the heterogeneously catalyzed gas-phase oxidation of n-butane to maleic anhydride. Here is a selection of the research findings: in the system TiO 2 / V 2 O 5 / P 2 O 5 the hitherto unknown orthophosphate (VO)Ti 6 (PO 4 ) 9 and the mixed crystal series Ti(P 1-x V x ) 2 O 7 (0 ≤ x ≤ 0,24; 0,30 ≤ x ≤ 0,43) with miscibility gap was detected. In the quasi-ternary system ZrO 2 / V 2 O 5 / P 2 O 5 the literature well described gapless solid solution Zr(P 1-x V x ) 2 O 7 was confirmed and investigated radiographically and by NMR spectroscopy. In the system Nb 2 O 5 / V 2 O 5 / P 2 O 5 the mixed crystal series Nb 1-x V x O(PO 4 ) (0 ≤ x ≤ 0,36), P 1-x V x Nb 9 O 25 (0 ≤ x ≤ 1) and NbOP 1-x V x O 4 (0 ≤ x ≤ 0,20) were found.

  10. Genetics Home Reference: glycogen storage disease type IV

    Science.gov (United States)

    ... Home Health Conditions Glycogen storage disease type IV Glycogen storage disease type IV Printable PDF Open All ... Javascript to view the expand/collapse boxes. Description Glycogen storage disease type IV (GSD IV) is an ...

  11. A cerium(IV)-carbon multiple bond

    Energy Technology Data Exchange (ETDEWEB)

    Gregson, Matthew; Lu, Erli; McMaster, Jonathan; Lewis, William; Blake, Alexander J.; Liddle, Stephen T. [Nottingham Univ. (United Kingdom). School of Chemistry

    2013-12-02

    Straightforward access to a cerium(IV)-carbene complex was provided by one-electron oxidation of an anionic ''ate'' cerium(III)-carbene precursor, thereby avoiding decomposition reactions that plague oxidations of neutral cerium(III) compounds. The cerium(IV)-carbene complex is the first lanthanide(IV)-element multiple bond and involves a twofold bonding interaction of two electron pairs between cerium and carbon. [German] Auf direktem Wege zu einem Cer(IV)-Carbenkomplex gelangt man durch die Einelektronenoxidation einer anionischen Carben-Cerat(III)-Vorstufe. So werden Zersetzungsprozesse vermieden, die die Oxidation neutraler Cer(III)-Verbindungen erschweren. Der Cer(IV)-Carbenkomplex enthaelt die erste Lanthanoid(IV)-Element-Mehrfachbindung; dabei binden Cer und Kohlenstoff ueber zwei Elektronenpaare.

  12. iväkoti Riemula

    OpenAIRE

    Alanko, Reetta; Ihanamäki, Katja

    2012-01-01

    Opinnäytetyössä kuvataan yleisesti päivähoidon kehitystä Suomessa sekä päivähoitoa yrittäjän näkökulmasta, tuoden esille sen tämän päivän haasteet ja mahdollisuudet. Työssä on pohdittu yhteistyön merkitystä kunnan kanssa ja sitä, miten kunta voi osaltaan joko rajoittaa tai edesauttaa yksityisen päivähoitoyrityksen toimintaa. Opinnäytetyössä kerrotaan teoriassa Päiväkoti Riemula nimisen, erityispäivähoitopalveluita tarjoavan yrityksen perustamiseen liittyvistä suunnitelmista. Suunnitelluss...

  13. Cognitive and Adaptive Skills in Toddlers Who Meet Criteria for Autism in DSM-IV but Not DSM-5

    Science.gov (United States)

    Jashar, Dasal Tenzin; Brennan, Laura A.; Barton, Marianne L.; Fein, Deborah

    2016-01-01

    The current study compared adaptive and cognitive skills, and autism severity of toddlers with an autism spectrum disorder (ASD) diagnosis under DSM-IV but not DSM-5 criteria (DSM-IV only group) to those who met autism criteria under both diagnostic systems (DSM-5 group) and to those without ASD (non-ASD group). The toddlers in the DSM-IV only…

  14. Generation of Dipeptidyl Peptidase-IV-Inhibiting Peptides from β-Lactoglobulin Secreted by Lactococcus lactis

    Directory of Open Access Journals (Sweden)

    Suguru Shigemori

    2014-01-01

    Full Text Available Previous studies showed that hydrolysates of β-lactoglobulin (BLG prepared using gastrointestinal proteases strongly inhibit dipeptidyl peptidase-IV (DPP-IV activity in vitro. In this study, we developed a BLG-secreting Lactococcus lactis strain as a delivery vehicle and in situ expression system. Interestingly, trypsin-digested recombinant BLG from L. lactis inhibited DPP-IV activity, suggesting that BLG-secreting L. lactis may be useful in the treatment of type 2 diabetes mellitus.

  15. OGLE-IV Transient Search report 26 August 2016

    Science.gov (United States)

    Wyrzykowski, L.; Sitek, M.; Kostrzewa-Rutkowska, Z.; Udalski, A.; Kozlowski, S.; Klencki, J.

    2016-08-01

    The OGLE-IV Transient Detection System (Wyrzykowski et al. 2014, AcA,64,197; Kozlowski et al. 2013; Klencki et al. 2016, AcA, 66,15) announces resumption of operation in the beginning of 2016B season and discovery of 45 new on-going transients.

  16. OGLE-IV Transient Search report 07 August 2015

    Science.gov (United States)

    Wyrzykowski, L.; Kostrzewa-Rutkowska, Z.; Udalski, A.; Kozlowski, S.; Poleski, R.; Pietrzynski, G.; Sitek, M.

    2015-08-01

    The OGLE-IV Transient Detection System (Wyrzykowski et al. 2014, AcA,64,197; Kozlowski et al. 2013) reports the discovery of 10 new transients. Most of them appeared near or on top of apparent galaxies and their light curves resemble those of supernovae near or after their peak brightness.

  17. Counsellors Respond to the DSM-IV-TR

    Science.gov (United States)

    Strong, Tom; Gaete, Joaquin; Sametband, Ines N.; French, Jared; Eeson, Jen

    2012-01-01

    The Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR) is an administrative fact for many counsellors. This psychiatric approach to formulating client concerns runs counter to those used by counsellors of many approaches (e.g., systemic, feminist). Using an online survey of counsellors (N = 116), invited contributions to a website…

  18. Improvement of Steam Generator Reliability for GEN-IV SFR

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Seong O; Kim Se Yun; Kim, Seok Hoon; Eoh, Jae Hyuk; Lee, Hyeong Yeon; Choi, Byung Seon

    2005-11-15

    The R and D items performed in this study were selected from the R and D task of ' Reliability improvement of Steam Generator' of GEN-IV SFR Component Design and BOP. Since this project deals with one of the most important issues for a GEN-IV SFR system, it needs to enhance the domestic technical backgrounds associated with the corresponding R and D items even for a very short period by 2005. This study provides the R and D results for i) Development of assessment methodology for dissimilar metal weld and ii) Development of multi-dimensional simulation methodology for a SWR event in a SFR steam generator.

  19. Improvement of Steam Generator Reliability for GEN-IV SFR

    International Nuclear Information System (INIS)

    Kim, Seong O; Kim Se Yun; Kim, Seok Hoon; Eoh, Jae Hyuk; Lee, Hyeong Yeon; Choi, Byung Seon

    2005-11-01

    The R and D items performed in this study were selected from the R and D task of ' Reliability improvement of Steam Generator' of GEN-IV SFR Component Design and BOP. Since this project deals with one of the most important issues for a GEN-IV SFR system, it needs to enhance the domestic technical backgrounds associated with the corresponding R and D items even for a very short period by 2005. This study provides the R and D results for i) Development of assessment methodology for dissimilar metal weld and ii) Development of multi-dimensional simulation methodology for a SWR event in a SFR steam generator

  20. The affinity plutonium(IV) for nitrogen donor ligands

    International Nuclear Information System (INIS)

    Jarvis, N.V.; Hancock, R.D.

    1994-01-01

    Established ligand design principles are used to predict the solution chemistry of Pu(IV) with nitrogen donor ligands which do not contain carboxylate donors. pK a 's of the nitrogen donors are lowered by addition of hydroxyalkyl groups causing Pu(IV) to have a greater affinity for these ligands than for hydroxide. Potentiometric studies using the ligands N,N,N'N',N''-pentakis(2-hydroxypropyl)-1,4,7-triazaheptane; N,N,N',N',N''-pentakis(2-hydroxyethyl)-1,4,7-triazaheptane; N,N,N',N',N'-tetrakis(2-hydroxyethyl)-1,2-diaminoethane; N,N,N',N'-tetrakis(2-hydroxyethyl)-trans-1,2-diaminocyclohexane; 1,4,8,11-tetrakis(2-hydroxyethyl)-1,4,8,11-tetraazacyclotetradecane and N,N-bis(2-hydroxyethyl)glycine with Pu(IV) showed that Pu(IV) has a considerable aqueous solution chemistry with these ligands. Data were processed by the ESTA library of programs and stability constants for all the systems are reported. Implications for selective ligand design for Pu(IV) are discussed. (orig.)

  1. Automatic generation and analysis of solar cell IV curves

    Science.gov (United States)

    Kraft, Steven M.; Jones, Jason C.

    2014-06-03

    A photovoltaic system includes multiple strings of solar panels and a device presenting a DC load to the strings of solar panels. Output currents of the strings of solar panels may be sensed and provided to a computer that generates current-voltage (IV) curves of the strings of solar panels. Output voltages of the string of solar panels may be sensed at the string or at the device presenting the DC load. The DC load may be varied. Output currents of the strings of solar panels responsive to the variation of the DC load are sensed to generate IV curves of the strings of solar panels. IV curves may be compared and analyzed to evaluate performance of and detect problems with a string of solar panels.

  2. I-V Curves from Photovoltaic Modules Deployed in Tucson

    Science.gov (United States)

    Kopp, Emily; Brooks, Adria; Lonij, Vincent; Cronin, Alex

    2011-10-01

    More than 30 Mega Watts of photo-voltaic (PV) modules are connected to the electric power grid in Tucson, AZ. However, predictions of PV system electrical yields are uncertain, in part because PV modules degrade at various rates (observed typically in the range 0% to 3 %/yr). We present I-V curves (PV output current as a function of PV output voltage) as a means to study PV module efficiency, de-ratings, and degradation. A student-made I-V curve tracer for 100-Watt modules will be described. We present I-V curves for several different PV technologies operated at an outdoor test yard, and we compare new modules to modules that have been operated in the field for 10 years.

  3. Tethys and Annex IV Progress Report for FY 2012

    Energy Technology Data Exchange (ETDEWEB)

    Hanna, Luke A.; Butner, R. Scott; Whiting, Jonathan M.; Copping, Andrea E.

    2013-09-01

    The marine and hydrokinetic (MHK) environmental Impacts Knowledge Management System, dubbed “Tethys” after the mythical Greek titaness of the seas, is being developed by the Pacific Northwest National Laboratory (PNNL) to support the U.S. Department of Energy’s Wind and Water Power Program (WWPP). Functioning as a smart database, Tethys enables its users to identify key words or terms to help gather, organize and make available information and data pertaining to the environmental effects of MHK and offshore wind (OSW) energy development. By providing and categorizing relevant publications within a simple and searchable database, Tethys acts as a dissemination channel for information and data which can be utilized by regulators, project developers and researchers to minimize the environmental risks associated with offshore renewable energy developments and attempt to streamline the permitting process. Tethys also houses a separate content-related Annex IV data base with identical functionality to the Tethys knowledge base. Annex IV is a collaborative project among member nations of the International Energy Agency (IEA) Ocean Energy Systems – Implementing Agreement (OES-IA) that examines the environmental effects of ocean energy devices and projects. The U.S. Department of Energy leads the Annex IV working with federal partners such as the Federal Energy Regulatory Commission (FERC), the Bureau of Ocean Energy Management (BOEM), and the National Oceanic Atmospheric Administration (NOAA). While the Annex IV database contains technical reports and journal articles, it is primarily focused on the collection of project site and research study metadata forms (completed by MHK researchers and developers around the world, and collected by PNNL) which provide information on environmental studies and the current progress of the various international MHK developments in the Annex IV member nations. The purpose of this report is to provide a summary of the content

  4. Extended analysis of Cu IV

    International Nuclear Information System (INIS)

    Meinders, E.; Uijlings, P.

    1980-01-01

    Wavelength data and classifications of 974 Cu IV lines in the region 750-1275 Angstroem are presented. Most of the lines have been classified as transitions from the previously unknown high even configurations 3d 7 5s and 3d 7 4d to 3d 7 4p. The configuration 3d 7 4d is seriously perturbed by 3d 6 4s 2 . The analysis resulted in the identification of 27 levels of 3d 7 5s and 113 levels of (3d 7 4d + 3d 6 4s 2 ) which are reported. The earlier published levels of 3d 7 4s and 3d 7 4p have to be shifted downward as a consequence of improved wavelength data. Radial paramter values, resulting from least-squares fits, are compared to Hartree-Fock values. The eigenvectors obtained in the parametric fitting are used to calculate transition probabilities in intermediate coupling. The relation between the observed intensities of the transitions 3d 7 4d-3d 7 4p and 3d 7 Ss-3d 7 4p is compared to the relation between theoretical values of the transition integrals obtained from Hartree-Fock calculations. A spectroscopic value for the ionization potentials is calculated from the 3d 7 ns configurations. (orig.)

  5. Studies of binary cerium(IV)-praseodymium(IV) and cerium(IV)-terbium(IV) oxides as pigments for ceramic applications

    International Nuclear Information System (INIS)

    Furtado, L.M.L.

    1991-01-01

    It was investigated a series of pigments of general composition Ce 1-x Pr x O 2 , and Ce x Tb y O 2 , exhibiting radish and brown colors, respectively, and high temperature stability. The pigments were obtained by dissolving appropriate amounts of the pure lanthanide oxides in acids and precipitating the rare earths as mixed oxalates, which were isolated and calcined under air, at 1000 0 C. X-Ray powder diffractograms were consistent with a cubic structure for the pigments. Magnetic susceptibility measurements, using Gouy method, indicated the presence of Pr(IV) ions in the Ce 1-x Pr x O 2 pigments and of Terbium predominantly as Tb(III) ions in the Ce-tb mixed oxides. A new method, based on suspension of solid samples in PVA-STB gels (STB = sodium tetradecaborate), was employed for the measurements of the electronic spectra of the pigments. The thermal behaviour the pigments was investigated by the calcination of the oxalates in the temperature range of 500 to 1200 O C, from 10 to 60 minutes. (author)

  6. Single-catheter approach for ablation of the slow pathway in a patient with type IV Ehlers-Danlos syndrome and AV nodal reentrant tachycardia using a magnetic navigation system

    NARCIS (Netherlands)

    T. Szili-Torok (Tamas); E. Jessurun; L.J.L.M. Jordaens (Luc)

    2008-01-01

    textabstractPatients with Ehlers-Danlos syndrome type IV have thin-walled, friable arteries and veins. Invasive procedures carry a significantly increased risk for perforation of blood vessels. The aim of this case report is to demonstrate the feasibility and potential benefits of using a

  7. Generation IV international forum 2002 - remarks

    International Nuclear Information System (INIS)

    Abraham, S.

    2002-01-01

    Analyses and forecasts underscore the important role of nuclear power in energy supply in the 21st century. Important aspects in this respect are the conservation of fossil resources, the protection of the world's climate, and the continuity of supply. Present 1st and 2nd generation nuclear power plants ensure an economical and technically mature electricity supply. Advanced systems offering, e.g., higher efficiency of fuel utilization, simplified systems technology, and advanced safety characteristics, can make available additional benefits in using nuclear power. Upon an initiative of the U.S. Department of Energy (DOE), ten countries combine their efforts in developing such reactor concepts in the Generation IV International Forum (GIF). Argentina, Brazil, Canada, France, Japan, South Africa, South Korea, Switzerland, the United Kingdom, and the United States pursue the common objective in GIF to identify suitable nuclear power systems and promote their development up to the envisaged readiness for construction in 2030. Besides technical and economic questions of nuclear power generation, also other aspects must be considered with a view to the future use of nuclear power. The particularly relevant issues, such as the management of radioactive waste, the intensification of research and development, and international cooperation, have been taken up by the Bush administration at an early point in time and have been, or will be, incorporated in practical solutions, as in the case of the Yucca Mountain repository project. (orig.)

  8. Zirconium (IV) complexes with some polymethylenediimines | Na ...

    African Journals Online (AJOL)

    The syntheses of zirconium (IV) complexes have been carried out by the reaction of oxozirconium (IV) chloride with the appropriate diimines (Schiff bases). The complexes were isolated as yellow solids which are stable to heat. The complexes were found to be insoluble in most solvents. The infrared spectra, elemental ...

  9. Astragaloside IV liposomes ameliorates adriamycin-induced ...

    African Journals Online (AJOL)

    Methods: The rats were given a single tail intravenous injection of adriamycin (6 mg/kg) within 1 week, and then divided into four groups including normal, model, benazepril and astragaloside IV liposomes group. They were all orally administered dosage of benazepril and astragaloside IV liposomes once daily for 8 weeks.

  10. Development of Basic Key Technologies for Gen IV SFR

    International Nuclear Information System (INIS)

    Han, Do Hee; Kim, Young In; Won, Byung Chool

    2008-11-01

    Technical specifications such as power capacity, type of core, clad alloy, clad barrier material, number of loops, type of SG tube have been evaluated and a optimal design concept has been identified to satisfy the technology goals of Generation IV nuclear systems. The concept for breakeven design is featured by the heat capacity of 1,200 MWe, enrichment-separated core, 2-loop, double-walled SG tube, and a long-life sensor system for in-service inspection

  11. Xylanase XYN IV from Trichoderma reesei showing exo- and endo-xylanase activity

    Science.gov (United States)

    A novel xylanase from Trichoderma reesei Rut C30, named XYN IV, was purified from the cellulolytic system of the fungus. The enzyme was discovered on its ability to attack aldotetraohexenuronic acid (HexA-2Xyl-4Xyl-4Xyl, HexA3Xyl3), releasing the reducing-end xylose residue. XYN IV exhibited catalyt...

  12. X-Band Electron Paramagnetic Resonance Comparison of Mononuclear Mn(IV)-oxo and Mn(IV)-hydroxo Complexes and Quantum Chemical Investigation of Mn(IV) Zero-Field Splitting.

    Science.gov (United States)

    Leto, Domenick F; Massie, Allyssa A; Colmer, Hannah E; Jackson, Timothy A

    2016-04-04

    X-band electron paramagnetic resonance (EPR) spectroscopy was used to probe the ground-state electronic structures of mononuclear Mn(IV) complexes [Mn(IV)(OH)2(Me2EBC)](2+) and [Mn(IV)(O)(OH)(Me2EBC)](+). These compounds are known to effect C-H bond oxidation reactions by a hydrogen-atom transfer mechanism. They provide an ideal system for comparing Mn(IV)-hydroxo versus Mn(IV)-oxo motifs, as they differ by only a proton. Simulations of 5 K EPR data, along with analysis of variable-temperature EPR signal intensities, allowed for the estimation of ground-state zero-field splitting (ZFS) and (55)Mn hyperfine parameters for both complexes. From this analysis, it was concluded that the Mn(IV)-oxo complex [Mn(IV)(O)(OH)(Me2EBC)](+) has an axial ZFS parameter D (D = +1.2(0.4) cm(-1)) and rhombicity (E/D = 0.22(1)) perturbed relative to the Mn(IV)-hydroxo analogue [Mn(IV)(OH)2(Me2EBC)](2+) (|D| = 0.75(0.25) cm(-1); E/D = 0.15(2)), although the complexes have similar (55)Mn values (a = 7.7 and 7.5 mT, respectively). The ZFS parameters for [Mn(IV)(OH)2(Me2EBC)](2+) were compared with values obtained previously through variable-temperature, variable-field magnetic circular dichroism (VTVH MCD) experiments. While the VTVH MCD analysis can provide a reasonable estimate of the magnitude of D, the E/D values were poorly defined. Using the ZFS parameters reported for these complexes and five other mononuclear Mn(IV) complexes, we employed coupled-perturbed density functional theory (CP-DFT) and complete active space self-consistent field (CASSCF) calculations with second-order n-electron valence-state perturbation theory (NEVPT2) correction, to compare the ability of these two quantum chemical methods for reproducing experimental ZFS parameters for Mn(IV) centers. The CP-DFT approach was found to provide reasonably acceptable values for D, whereas the CASSCF/NEVPT2 method fared worse, considerably overestimating the magnitude of D in several cases. Both methods were poor in

  13. Direct healthcare costs and cost-effectiveness of acute coronary syndrome secondary prevention with ticagrelor compared to clopidogrel: economic evaluation from the public payer's perspective in Poland based on the PLATO trial results.

    Science.gov (United States)

    Pawęska, Justyna; Macioch, Tomasz; Perkowski, Piotr; Budaj, Andrzej; Niewada, Maciej

    2014-01-01

    Ticagrelor is the first reversibly binding oral P2Y12 receptor antagonist designed to reduce clinical thrombotic events in patients with acute coronary syndrome (ACS). Compared to clopidogrel, ticagrelor has been proven to significantly reduce the rate of death from vascular causes, myocardial infarction (MI), or stroke without an increase in the rate of overall major bleeding in patients who have an ACS with or without ST-segment elevation (STEMI and NSTEMI) or unstable angina (UA). To evaluate the cost-effectiveness and healthcare costs associated with secondary prevention of ACS using ticagrelor or clopidogrel in patients after STEMI, NSTEMI and UA. An economic model based on results from the PLATO trial was used to evaluate the cost-effectiveness of one-year therapy with ticagrelor or clopidogrel. The structure of the model consisted of two parts, i.e. the decision tree with one-year PLATO results and the Markov model with lifelong estimations, which exceeded PLATO follow-up data. The model was adjusted to Polish settings with country-specific data on death rates in the general population and direct medical costs calculated from the public payer's perspective. Costs were derived from the National Health Fund (NHF) and the Ministry of Health and presented in PLN 2013 values. Annual mean costs of second and subsequent years after stroke or MI were obtained from the literature. Uncertainty of assumed parameters was tested in scenarios and probabilistic sensitivity analyses. The adopted model allowed the estimation of an incremental cost-effectiveness ratio for life years gained (LYG) and an incremental cost-utility ratio for quality adjusted life years (QALY). Total direct medical costs to the public payer at a one year horizon were 2,905 PLN higher with ticagrelor than with clopidogrel. However, mean healthcare costs at a one year horizon (excluding drug costs and concomitant drugs) were 690 PLN higher for patients treated with clopidogrel. In a lifetime horizon

  14. LAS CRÍTICAS DE ARISTÓTELES A PLATÓN EN METAFÍSICA I, 9 ARISTOTLE’S CRITICISMS OF PLATO IN METAPHYSICS I, 9

    Directory of Open Access Journals (Sweden)

    Silvana Gabriela Di Camillo

    2011-03-01

    Full Text Available

    O recurso à exposição crítica das doutrinas anteriores é um procedimento metodológico usual em Aristóteles. Mas a característica distintiva do Livro I da Metafísica é que, ao invés de estabelecer uma nova doutrina, o exame dos predecessores serve para confirmar os próprios conceitos aristotélicos, os quais ele usa para avaliar os êxitos e os erros das doutrinas analisadas. Essa imposição de conceitos próprios lhe valeu a acusação de ter uma compreensão histórica distorcida. Com a análise detalhada das críticas da teoria platônica das Idéias na Metafísica I, 9, pretendemos mostrar: a que as críticas de manipulação e distorção das opiniões dos seus antecessores ofuscam o grau em que as suas próprias posições emergem de uma análise crítica do pensamento anterior; e b que a imposição de conceitos próprios não é uma distorção, mas uma proposta de solução para os problemas que as teorias anteriores deixaram sem solução.

    The use of critical exposition of previous doctrines is a methodological procedure usual in Aristotle. But the distinctive characteristic of Book I of the Metaphysics is that, rather than to establish a new doctrine, a review of  predecessors serves to confirm the own concepts to be used in the evaluation of the doctrines examined. This imposition of own terms has cost him the charge of distorting historical understanding. With the detailed analysis of the criticisms of Plato's theory of Ideas in Metaphysics I, 9, we intend to show a that the criticism of manipulation and distortion of his predecessors' views overshadow the degree to which Aristotle's own positions emerge from a critical review of previous thought and b that the

  15. Environmental, financial and energy feasibility of the electrolysis of the water steam of a generation IV reactor cooling system during the moments of low consumption ef eletrical energy: challenges and perspectives

    International Nuclear Information System (INIS)

    Stefanelli, Eduardo J.; Vargas, Miltom; Garcia, Pedro L.; Seo, Emilia S.M.; Oliveira, Wagner de S.

    2009-01-01

    Our civilization is in an inflection moment. Our current decisions will lead us to drastic changes in the planet climate or to cleaner and more sustainable energy generation models. In a certain moment in the evolution of our society, we have privileged the productivity instead of the reasonable use of the planet's resources. This option has been leading us to a situation in which these resources are seriously jeopardized. New models of energy generation and use should be discussed and adopted in order to reverse this process. The electric-power consumption is not constant through time and it must be generated at the moment it is going to be used. There are moments of great idleness in the electric-power generation system, counterbalanced by high demand moments. This characteristic has induced us to the construction of a model of great generation capacity that remains without use most of the time, producing huge financial and environmental impacts. In this article, we discuss the environmental, financial and energy viability of using the idle capacity of the electric-power system to, through water steam electrolysis, produce hydrogen, which would be reconverted into electric power in peak moments by a fuel cell. In this study, we aim at investigating the viability of associating a SOFC (Solid Oxide Fuel Cell), acting as an electrolysis bow, to a generation IV reactor, in order to produce hydrogen from superheated water steam in the cooling of the reactor, which will be converted into electric power via SOFC (Solid Oxide Fuel Cell) in peak moments. The method used in this investigation was to study the electric charge variation consumed in a day, randomly selected in relation to the hour of the day, to launch a curve into a diagram 'Demand x hour of the day', to establish the peak moments, the minimum moments, and the average consumption, and, based on these data and geometrically, predict the viability of using the energetic potential of the moments in which the

  16. Environmental, financial and energy feasibility of the electrolysis of the water steam of a generation IV reactor cooling system during the moments of low consumption ef eletrical energy: challenges and perspectives

    Energy Technology Data Exchange (ETDEWEB)

    Stefanelli, Eduardo J.; Vargas, Miltom; Garcia, Pedro L.; Seo, Emilia S.M.; Oliveira, Wagner de S. [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)], e-mail: ipen@stefanelli.eng.br

    2009-07-01

    Our civilization is in an inflection moment. Our current decisions will lead us to drastic changes in the planet climate or to cleaner and more sustainable energy generation models. In a certain moment in the evolution of our society, we have privileged the productivity instead of the reasonable use of the planet's resources. This option has been leading us to a situation in which these resources are seriously jeopardized. New models of energy generation and use should be discussed and adopted in order to reverse this process. The electric-power consumption is not constant through time and it must be generated at the moment it is going to be used. There are moments of great idleness in the electric-power generation system, counterbalanced by high demand moments. This characteristic has induced us to the construction of a model of great generation capacity that remains without use most of the time, producing huge financial and environmental impacts. In this article, we discuss the environmental, financial and energy viability of using the idle capacity of the electric-power system to, through water steam electrolysis, produce hydrogen, which would be reconverted into electric power in peak moments by a fuel cell. In this study, we aim at investigating the viability of associating a SOFC (Solid Oxide Fuel Cell), acting as an electrolysis bow, to a generation IV reactor, in order to produce hydrogen from superheated water steam in the cooling of the reactor, which will be converted into electric power via SOFC (Solid Oxide Fuel Cell) in peak moments. The method used in this investigation was to study the electric charge variation consumed in a day, randomly selected in relation to the hour of the day, to launch a curve into a diagram 'Demand x hour of the day', to establish the peak moments, the minimum moments, and the average consumption, and, based on these data and geometrically, predict the viability of using the energetic potential of the moments

  17. Adduct formation in Ce(IV) thenolytrifluoroacetonate

    International Nuclear Information System (INIS)

    Anufrieva, S.I.; Polyakova, G.V.; Snezhko, N.I.; Pechurova, N.I.; Martynenko, L.I.; Spitsyn, V.I.

    1982-01-01

    The literature contains no information on adduct formation in Ce(IV) β-diketonates with additional ligands. Since tetrakis-β-diketonates of Ce(IV) have four six-membered chelate rings, we can suppose that the introduction of an additional monodentate or bidentate ligand into the coordination sphere of Ce(IV) β-diketonates would lead to an increase in the coordination number (CN) of the Ce(IV) to nine or ten. The possibility of realization of such a high CN for Ce(IV) has not been proved; a study of adduct formation by Ce(IV) tetrakis-β-diketonates is thus of theoretical interest. Such an investigation might also be of practical interest, because the introduction of an additional ligand into the coordination sphere of a rare-earth β-diketonate usually increases the solubility of the β-diketonate in nonpolar solvents and increases the volatility of the compound; such a modification of the properties is important for various practical purposes. The aim of our work was to study the possibility of separating solid adducts of Ce(IV) tetrakis-thenoyltrifluoroacetonate with certain oxygen-containing and nitrogen-containing donor monodentate and bidentate ligands, and also to investigate their properties. As the β-diketone we used thenoyltrifluoroacetone (HTTFA), since in a parallel investigation it was found that Ce(TTFA) 4 has a high oxidation-reduction stability

  18. Market opportunities: U.S. - PADD IV

    International Nuclear Information System (INIS)

    Garner, R.P.

    1997-01-01

    The current supply and demand balance, the short and long term expectations and marketing opportunities for Canadian crude oil in PADD IV, the Rocky Mountain region in the US, were reviewed. It was suggested that market opportunities in PADD IV are derived from the following four factors: (1) crude oil declines within that area, (2) federal regulations, (3) competitive presence with markets, and (4) population growth. The overall conclusion was that Canadian producers and PADD IV refiners will be looking at an ever-growing relationship based on freight equalized world crude prices. 8 tabs., 5 figs

  19. Androgynes et gynandres : la relecture péladanienne du Banquet de Platon // Androgynes and gynandres : The Péladan’s reinterpretation of the Symposium by Plato

    Directory of Open Access Journals (Sweden)

    Eva Voldřichová Beránková

    2015-12-01

    Full Text Available The Symposium alias The Banquet belongs to those hypotexts by Plato which have been constantly reread and reinterpreted by the authors of French decadence. This article is focused on the Péladan’s reinterpretation of one of its parts, the famous Aristophanes’s speech about love. It implies on one hand the masculine notion of “androgyne”, heavily valorised in the fin de siècle novels, and, on the other hand, the feminine concept of “gynandre”, perceived negatively, feared and mocked. Why in Péladan’s (1858–1918 eyes and according to many others decadent authors man is gorgeous and intelligent enough to realize on his own the platonic ideal of the union of the two sexes? And what about the woman, henceforth outmoded and “useless”? The decadent misogyny ties itself in knots over its fanciful theories which are reflective of the spirit of this historical period.

  20. AMOS Phase IV Annual Report

    Science.gov (United States)

    1980-06-01

    Microthermal Probe System; 2) Acoustic Sounder; 3) Star Sensor; and i 4) Seeing Monitor. Thý in ..ru. cn.tat -ion, much of it one-of-a-kind prototype...profiles of C 2 N2 3) Acoustic Sounder: an instrument that measures C to 300 m altitude; 4) Microthermal Probes: two systems, consisting of three 2...atmospheric program produced - 146 - Y- MICROTHERMAL NICRPHMERI-AL PROBES (3) _j PPRBES (3) WIND SPEED & WIND SPEED & DIRECTION ---- I- DIRECTION

  1. Diorganotin(IV) Complexes with Methionine Methyl Ester. Equilibria ...

    African Journals Online (AJOL)

    IV) (DBT) and diphenyltin(IV) (DPT) was investigated at 25 °C and 0.1 mol dm–3 ionic strength in water for dimethyltin(IV) and in 50 % dioxane–water mixture for dibutyltin(IV) and diphenyltin(IV). Methionine methyl ester forms1:1 and 1:2 ...

  2. Periodontal Disease Part IV: Periodontal Infections

    OpenAIRE

    Turnbull, Robert S.

    1988-01-01

    In Part IV of this article, the author describes two periodontal infections, acute necrotizing ulcerative gingivitis (trench mouth) and periodontal abscess, both acute painful conditions for which patients may seek advice from their family physician rather than their dentist.

  3. Determination of uranium (IV) by flow voltammetry

    International Nuclear Information System (INIS)

    Ding Anqing

    1987-01-01

    According to the quantitative reaction of U(IV) and Fe(III) in H 2 SO 4 as well as the relation between current and concentration of substance detected, U(IV) has been determined indirectly by measurement of the electrolysis current of residual Fe(III). The columniform electrode used is made of glass carbon particles. At the range of U(IV) from a few micrograms to 40 μg, the linear relation is excellent. The relative standard deviation is within ±4%. The interference of Fe(II), Ti(IV) and U(VI) is negligible but of Ti(III) is serious. This method has been successfully applied in the determination of actual samples (both out line and on line). Main advantages of this procedure are rapid, simple, small amount of sample (only at microgram level) and easy to realize automation, able to use for on line or process analysis

  4. Genetics Home Reference: mucopolysaccharidosis type IV

    Science.gov (United States)

    ... enzymes, GAGs accumulate within cells, specifically inside the lysosomes . Lysosomes are compartments in the cell that break down ... that cause molecules to build up inside the lysosomes are called lysosomal storage disorders. In MPS IV, ...

  5. Dsm-iv hypochondriasis in primary care

    OpenAIRE

    Escobar, JI; Gara, M; Waitzkin, H; Silver, RC; Holman, A; Compton, W

    1998-01-01

    The object of this study was to assess the prevalence and correlates of the DSM-IV diagnosis of hypochondriasis in a primary care setting. A large sample (N = 1456) of primary care users was given a structured interview to make diagnoses of mood, anxiety, and somatoform disorders and estimate levels of disability. The prevalence of hypochondriasis (DSM-IV) was about 3%. Patients with this disorder had higher levels of medically unexplained symptoms (abridged somatization) and were more impair...

  6. COBRA-IV wire wrap data comparisons

    International Nuclear Information System (INIS)

    Donovan, T.E.; George, T.L.; Wheeler, C.L.

    1979-02-01

    Thermal hydraulic analyses of hexagonally packed wire-wrapped fuel assemblies are complicated by the induced crossflow between adjacent subchannels. The COBRA-IV computer code simultaneously solves the hydrodynamics and thermodynamics of fuel assemblies. The modifications and the results are presented which are predicted by the COBRA-IV calculation. Comparisons are made with data measured in five experimental models of a wire-wrapped fuel assembly

  7. NUCLEAR ENERGY RESEARCH INITIATIVE (NERI) PROGRAM GRANT NUMBER DE-FG03-00SF22168 TECHNICAL PROGRESS REPORT (Aug 15, 2002 to Nov. 15, 2002) - DESIGN AND LAYOUT CONCEPTS FOR COMPACT, FACTORY-PRODUCED, TRANSPORTABLE GENERATION IV REACTOR SYSTEMS

    International Nuclear Information System (INIS)

    Fred R. Mynatt; Andy Kadak; Marc Berte; Larry Miller; Lawrence Townsend; Martin Williamson; Rupy Sawhney; Jacob Fife

    2002-01-01

    The objectives of this project are to develop and evaluate nuclear power plant designs and layout concepts to maximize the benefits of compact modular Generation IV reactor concepts including factory fabrication and packaging for optimal transportation and siting. This report covers the ninth quarter of the project. The three reactor concept teams have completed initial plant concept development, evaluation and layout. A significant design effort has proceeded with substantial change and evolution from original ideas. The concepts have been reviewed by the industry participants and improvements have been implemented. The third phase, industrial engineering simulation of reactor fabrication has begun

  8. Workshop 97. Part IV. Proceedings

    International Nuclear Information System (INIS)

    1996-12-01

    This volume of the Proceedings cover the following branches of science and technology: preservation and creation of the environment, architecture, town planning and visual arts, reliability, production systems and technology, nuclear engineering, transport engineering, and economics and business activities. Out of the contributions, 19 have been input to INIS. (P.A.)

  9. OGLE-IV Transient Search summary of season 2015b

    Science.gov (United States)

    Wyrzykowski, L.; Kostrzewa-Rutkowska, Z.; Klencki, J.; Sitek, M.; Mroz, P.; Udalski, A.; Kozlowski, S.; Skowron, J.; Poleski, R.; Szymanski, M. K.; Pietrzynski, G.; Soszynski, I.; Ulaczyk, K.; Pietrukowicz, P.

    2015-12-01

    The OGLE-IV Transient Detection System (Wyrzykowski et al. 2014, AcA,64,197; Kozlowski et al. 2013) in the 2015b transient observing season (from August) has been operating in dual mode: regular as in previous years (detections every couple of days based on at least two positive detections), and rapid (automatised detections within 15 mins after the single frame was taken, details in Klencki et al. in prep.).

  10. Hafnium(IV) complexation with oxalate at variable temperatures

    Energy Technology Data Exchange (ETDEWEB)

    Friend, Mitchell T.; Wall, Nathalie A. [Washington State Univ., Pullmanm, WA (United States). Dept. of Chemistry

    2017-08-01

    Appropriate management of fission products in the reprocessing of spent nuclear fuel (SNF) is crucial in developing advanced reprocessing schemes. The addition of aqueous phase complexing agents can prevent the co-extraction of these fission products. A solvent extraction technique was used to study the complexation of Hf(IV) - an analog to fission product Zr(IV) - with oxalate at 15, 25, and 35 C in 1 M HClO{sub 4} utilizing a {sup 175+181}Hf radiotracer. The mechanism of the solvent extraction system of 10{sup -5} M Hf(IV) in 1 M HClO{sub 4} to thenoyltrifluoroacetone (TTA) in toluene demonstrated a 4{sup th}-power dependence in both TTA and H{sup +}, with Hf(TTA){sub 4} the only extractable species. The equilibrium constant for the extraction of Hf(TTA){sub 4} was determined to be log K{sub ex}=7.67±0.07 (25±1 C, 1 M HClO{sub 4}). The addition of oxalate to the aqueous phase decreased the distribution ratio, indicating aqueous Hf(IV)-oxalate complex formation. Polynomial fits to the distribution data identified the formation of Hf(ox){sup 2+} and Hf(ox){sub 2(aq)} and their stability constants were measured at 15, 25, and 35 C in 1 M HClO{sub 4}. van't Hoff analysis was used to calculate Δ{sub r}G, Δ{sub r}H, and Δ{sub r}S for these species. Stability constants were observed to increase at higher temperature, an indication that Hf(IV)-oxalate complexation is endothermic and driven by entropy.

  11. Type IV Wind Turbine Model

    DEFF Research Database (Denmark)

    Hansen, Anca Daniela; Margaris, Ioannis D.

    . In the project, this wind turbine model will be further incorporated in a wind power plant model together with the implementation in the wind power control level of the new control functionalities (inertial response, synchronising power and power system damping). For this purpose an aggregate wind power plant......This document is created as part of the EaseWind project. The goal of this project is to develop and investigate new control features for primary response provided by wind power plants. New control features as inertial response, synchronising power and power system damping are of interest to EaseWind...... project to be incorporated in the wind power plant level. This document describes the Type 4 wind turbine simulation model, implemented in the EaseWind project. The implemented wind turbine model is one of the initial necessary steps toward integrating new control services in the wind power plant level...

  12. Synthesis and characterization of chiral thorium(IV) and uranium(IV) benzamidinate complexes

    Energy Technology Data Exchange (ETDEWEB)

    Schoene, Sebastian; Maerz, Juliane; Kaden, Peter; Patzschke, Michael; Ikeda-Ohno, Atsushi [Helmholtz-Zentrum Dresden-Rossendorf e.V., Dresden (Germany). Chemistry of the F-Elements

    2017-06-01

    Two chiral benzamidinate complexes of tetravalent actinides (Th(IV) and U(IV)) were synthesized using a salt metathesis reaction of the corresponding actinide(IV) tetrachlorides and the potassium salt of the chiral benzamidine (S,S)-N,N-Bis-(1-phenylethyl)-benzamidine ((S)-HPEBA). The structure of the complexes was determined with single crystal X-ray diffraction. These are the first examples of chiral amidinate complexes of actinides.

  13. Nuclear fission today and tomorrow: from renaissance to technological breakthrough (Generation IV)

    International Nuclear Information System (INIS)

    Van Goethem, G.

    2010-01-01

    This paper describes briefly the major scientific and technological challenges related to the very innovative nuclear fission reactor systems to be deployed at the horizon 2040 (called Generation IV). The paper focuses on the benefits of the Generation IV systems, according to criteria or technology goals established at the international level (Generation IV International Forum (GIF)). This goals are drastic improvements on four areas: sustainable development, industrial competitiveness, safety and reliability and proliferation resistance. The focus is on the design objectives and associated research issues that have been agreed upon internationally to meet these four ambitious goals. (author)

  14. Study of the oxidation-reduction kinetics involved in the Np(V) + Fe(II) in equilibrium Np(IV) + Fe(III) system in nitric acid solutions

    International Nuclear Information System (INIS)

    Jao, Y.

    1975-08-01

    Ferrous nitrate-hydrazine is one of the more attractive alternate reactants to the currently used reagent, ferrous sulfamate, for partitioning plutonium from neptunium and uranium. An understanding of the kinetics of the reduction of Np(VI) to Np(IV) by ferrous nitrate-hydrazine is needed before a satisfactory evaluation of the feasibility of this reductant in actinide element separations can be made. The purpose of this work was to study the kinetics and mechanisms of the reduction of Np(V) by Fe(II) and the oxidation of Np(IV) by Fe(III) in 1-2 M nitric acid solutions. The acid concentration range was chosen to include that typically used in the separation of plutonium from neptunium and uranium by solvent extraction with tributylphosphate. The forward and reverse rate constants, hydrogen ion dependence, temperature dependence, ionic strength effects and nitrate ion influence were determined. The proposed reaction mechanisms involve protonation of the NpO 2 + ions and hydroxyoxygenation of Np 4 + ions. (LK)

  15. Safety Design Criteria (SDC) for Gen-IV Sodium-cooled Fast Reactor

    International Nuclear Information System (INIS)

    Nakai, Ryodai

    2013-01-01

    SDC Development Background & Objectives: • Safety Design Criteria (SDC) Development for Gen-IV SFR: – Proposed at the GIF Policy Group (PG) meeting in October 2010 –SDC “harmonization” is increasingly important for: • Realization of enhanced safety designs meeting to Gen-IV safety goals and safety approach common to SFR systems; • Preparation for the forthcoming licensing in the near future; • Because Gen-IV SFR are progressing into conceptual design stage. • The SDC is the Reference criteria: – Of the designs of safety-related Structures, Systems & Components that are specific to the SFR system; – For clarifying the requisites systematically & comprehensively; – When the technology developers apply the basic safety approach and use the codes & standards for conceptual design of the Gen-IV SFR system

  16. The Pearson IV distribution and its application to ion implanted depth profiles

    International Nuclear Information System (INIS)

    Wilson, R.G.

    1980-01-01

    The Pearson IV distribution system is analyzed to determine the regions of validity for the values of the moments that produce convex, concave, more pointed than Gaussian, and more flat-topped than Gaussian distributions; the limits beyond which no significant change in distribution is produced; and excluded regions. These regions are illustrated in a figure that can be used to facilitate the determination of the Pearson IV moments for experimental ion implanted depth distributions. Examples are given of Pearson IV distributions to illustrate the effects of the ranges of skewness, kurtosis, and standard deviation, for both more pointed and more flat-topped than Gaussian distributions. A procedure is described for matching experimental ion implanted depth distributions to computer plotted Pearson IV modified Gaussian distributions. A few experimental curves are given to illustrate the different types of Pearson IV curves, and accuracies of moments are discussed. (author)

  17. Annual report 1990 annex IV

    International Nuclear Information System (INIS)

    Smith, B.; Foskolos, K.

    1991-01-01

    The Nuclear Energy Research Department consists of three Laboratories: Reactor Physics and Systems Engineering (LRS), Thermal Hydraulics (LTH), and Materials and Nuclear Processes (LWV). There are additionally two Research Programmes: 'Waste Disposal' (PES) and LWR-Safety (PLS). The Department's activities focus on three main areas: safety and safety-related operational problems of the Swiss nuclear power plants (NPPs), contributions to the issues involved in radioactive waste disposal, future reactors. In addition, scientific-technical services are provided in the nuclear and non-nuclear sectors and for the operation of the relevant site facilities. (author) figs., tabs., refs

  18. Plutonium(IV) precipitates formed in alkaline media in the presence of various anions

    Energy Technology Data Exchange (ETDEWEB)

    Krot, N.N.; Shilov, V.P.; Yusov, A.B.; Tananaev, I.G.; Grigoriev, M.S.; Garnov, A.Yu.; Perminov, V.P.; Astafurova, L.N.

    1998-09-01

    The tendency of Pu(IV) to hydrolyze and form true solutions, colloid solutions, or insoluble precipitates has been known since the Manhattan Project. Since then, specific studies have been performed to examine in detail the equilibria of Pu(IV) hydrolytic reactions in various media. Great attention also has been paid to the preparation, structure, and properties of Pu(IV) polymers or colloids. These compounds found an important application in sol-gel technology for the preparation of nuclear fuel materials. A most important result of these works was the conclusion that Pu(IV) hydroxide, after some aging, consists of very small PuO{sub 2} crystallites and should therefore be considered to be Pu(IV) hydrous oxide. However, studies of the properties and behavior of solid Pu(IV) hydroxide in complex heterogeneous systems are rare. The primary goal of this investigation was to obtain data on the composition and properties of Pu(IV) hydrous oxide or other compounds formed in alkaline media under different conditions. Such information is important to understand Pu(IV) behavior and the forms of its existence in the Hanford Site alkaline tank waste sludge. This knowledge then may be applied in assessing plutonium criticality hazards in the storage, retrieval, and treatment of Hanford Site tank wastes as well as in understanding its contribution to the transuranic waste inventory (threshold at 100 nCi/g or about 5 {times} 10{sup {minus}6} M) of the separate solution and solid phases.

  19. Formation of U(IV) Nanoparticles and Their Growth Mechanism in Mildly Acidic Aqueous Phases

    Energy Technology Data Exchange (ETDEWEB)

    Cha, Wan Sik; Kim, Sun Tae; Cho, Hye Ryun; Jung, Euo Chang [KAERI, Daejeon (Korea, Republic of)

    2016-05-15

    Previous studies suggest that U(IV) nanoparticle (NP) formation is one of key steps in mineralization or immobilization of uranium which can be mediated either by microbes or by abiotic geochemical reactions. Colloidal NPs in a groundwater system are potential carrier phases influencing RN migration in subsurface environment. However, the mechanism of U(IV) NP formation and the potential reaction intermediates during this solid phase formation process have not been elucidated in detail so far. In this study we attempted to examine the U(IV) nanoparticle formation reactions preceded by the hydrolysis of U{sup 4+} at different pHs, concentrations and temperatures. The kinetics of U(IV) NP formation from dissolved U(IV) species was monitored under mildly acidic conditions (pH 2 ∼ 3) mainly by using UV-Vis absorption spectrophotometry. Dynamic light scattering (DLS) analysis, nanoparticle tracking analysis (NTA) and transmission electron microscopy (TEM) were used to characterize the NPs produced during the reactions. The results demonstrate that the U(IV) NP formation process is very sensitive toward temperature variation. The main outcome of this study is the discovery of the autocatalytic nature of U(IV) NP formation from the supersaturated U(OH){sup 3+} solution in a mildly acidic aqueous solution. The structure of reaction intermediates is proposed to contain oxide linkage. In the presentation the proposed mechanism of the U(IV) NP formation reaction and the properties of primary NPs and their clusters will be discussed in detail.

  20. Peroxidasin-mediated crosslinking of collagen IV is independent of NADPH oxidases

    Directory of Open Access Journals (Sweden)

    Gábor Sirokmány

    2018-06-01

    Full Text Available Collagen IV is a major component of the basement membrane in epithelial tissues. The NC1 domains of collagen IV protomers are covalently linked together through sulfilimine bonds, the formation of which is catalyzed by peroxidasin. Although hydrogen peroxide is essential for this reaction, the exact source of the oxidant remains elusive. Members of the NOX/DUOX NADPH oxidase family are specifically devoted to the production of superoxide and hydrogen peroxide. Our aim in this study was to find out if NADPH oxidases contribute in vivo to the formation of collagen IV sulfilimine crosslinks. We used multiple genetically modified in vivo model systems to provide a detailed assessment of this question. Our data indicate that in various peroxidasin-expressing tissues sulfilimine crosslinks between the NC1 domains of collagen IV can be readily detected in the absence of functioning NADPH oxidases. We also analyzed how subatmospheric oxygen levels influence the collagen IV network in collagen-producing cultured cells with rapid matrix turnover. We showed that collagen IV crosslinks remain intact even under strongly hypoxic conditions. Our hypothesis is that during collagen IV network formation PXDN cooperates with a NOX/DUOX-independent H2O2 source that is functional also at very low ambient oxygen levels. Keywords: Peroxidasin, NADPH oxidase, Hydrogen peroxide, Collagen IV, Sulfilimine

  1. Plutonium(IV) precipitates formed in alkaline media in the presence of various anions

    International Nuclear Information System (INIS)

    Krot, N.N.; Shilov, V.P.; Yusov, A.B.; Tananaev, I.G.; Grigoriev, M.S.; Garnov, A.Yu.; Perminov, V.P.; Astafurova, L.N.

    1998-09-01

    The tendency of Pu(IV) to hydrolyze and form true solutions, colloid solutions, or insoluble precipitates has been known since the Manhattan Project. Since then, specific studies have been performed to examine in detail the equilibria of Pu(IV) hydrolytic reactions in various media. Great attention also has been paid to the preparation, structure, and properties of Pu(IV) polymers or colloids. These compounds found an important application in sol-gel technology for the preparation of nuclear fuel materials. A most important result of these works was the conclusion that Pu(IV) hydroxide, after some aging, consists of very small PuO 2 crystallites and should therefore be considered to be Pu(IV) hydrous oxide. However, studies of the properties and behavior of solid Pu(IV) hydroxide in complex heterogeneous systems are rare. The primary goal of this investigation was to obtain data on the composition and properties of Pu(IV) hydrous oxide or other compounds formed in alkaline media under different conditions. Such information is important to understand Pu(IV) behavior and the forms of its existence in the Hanford Site alkaline tank waste sludge. This knowledge then may be applied in assessing plutonium criticality hazards in the storage, retrieval, and treatment of Hanford Site tank wastes as well as in understanding its contribution to the transuranic waste inventory (threshold at 100 nCi/g or about 5 x 10 -6 M) of the separate solution and solid phases

  2. Solubility study of Tc(IV) oxides

    International Nuclear Information System (INIS)

    Liu, D.J.; Fan, X.H.

    2005-01-01

    The deep geological disposal of the high level radioactive wastes is expected to be a safer disposal method in most countries. The long-lived fission product 99 Tc is present in large quantities in nuclear wastes and its chemical behavior in aqueous solution is of considerable interest. Under oxidizing conditions technetium exists as the anionic species TcO 4 - whereas under the reducing conditions, expected to exist in a deep geological repository, it is generally predicted that technetium will be present as TcO 2 ·nH 2 O. Hence, the mobility of Tc(IV) in reducing groundwater may be limited by the solubility of TcO 2 ·nH 2 O under these conditions. Due to this fact it is important to investigate the solubility of TcO 2 ·nH 2 O. The solubility determines the release of radionuclides from waste form and is used as a source term in radionuclide migration analysis in performance assessment of radioactive waste repository. Technetium oxide was prepared by reduction of a technetate solution with Sn 2 + . The solubility of Tc(IV) oxide has been determined in simulated groundwater and redistilled water under aerobic and anaerobic conditions. The effects of pH and CO 3 2- concentration of solution on solubility of Tc(IV) oxide were studied. The concentration of total technetium and Tc(IV) species in the solutions were periodically determined by separating the oxidized and reduced technetium species using a solvent extraction procedure and counting the beta activity of the 99 Tc with a liquid scintillation counter. The experimental results show that the rate of oxidation of Tc(IV) in simulated groundwater and redistilled water is about (1.49-1.86) x 10 -9 mol/(L·d) under aerobic conditions, but Tc(IV) in simulated groundwater and redistilled water is not oxidized under anaerobic conditions. Under aerobic or anaerobic conditions the solubility of Tc(IV) oxide in simulated groundwater and redistilled water is equal on the whole after centrifugation or ultrafiltration. The

  3. Solubility of Tc(IV) oxides

    International Nuclear Information System (INIS)

    Liu, D.J.; Fan, X.H.

    2005-01-01

    Full text of publication follows: The deep geological disposal of the high level radioactive wastes is expected to be a safer disposal method in most countries. The long-lived fission product 99 Tc is present in large quantities in nuclear wastes and its chemical behavior in aqueous solution is of considerable interest. Under the reducing conditions, expected to exist in a deep geological repository, it is generally predicted that technetium will be present as TcO 2 .nH 2 O. The solubility of Tc(IV) is used as a source term in performance assessment of radioactive waste repository. Technetium oxide was prepared by reduction of a technetate solution with Sn 2+ . The solubility of Tc(IV) oxide has been determined in simulated groundwater and re-distilled water under aerobic and anaerobic conditions. The effects of pH and CO 3 2- concentration of solution on solubility of Tc(IV) oxide were studied. The concentration of total technetium and Tc(IV) species in the solutions were periodically determined by separating the oxidized and reduced technetium species using a solvent extraction procedure and counting the beta activity of the 99 Tc with a liquid scintillation counter. The experimental results show that the rate of oxidation of Tc(IV) in simulated groundwater and re-distilled water is about (1.49∼1.86) x 10 -9 mol/(L.d) under aerobic conditions, but Tc(IV) in simulated groundwater and re-distilled water is not oxidized under anaerobic conditions. Under aerobic or anaerobic conditions the solubility of Tc(IV) oxide in simulated groundwater and re-distilled water is equal on the whole after centrifugation or ultrafiltration. The solubility of Tc(IV) oxide decreases with the increase of pH at pH 10 and is pH independent in the range 2 -8 to 10 -9 mol/L at 2 3 2- concentration. These data could be used to estimate the Tc(IV) solubility for cases where solubility limits transport of technetium in reducing environments of high-level waste repositories. (authors)

  4. Tracer techniques in electroplating. IV

    International Nuclear Information System (INIS)

    Stverak, B.; Rousar, I.

    1979-01-01

    In copper extraction from a solution containing trace amounts of silver the extraction of silver is controlled by diffusion. Mass transfer coefficients may be determined from the surface density of the extracted silver. The values are used in designing a system with suitable mixing for even mass distribution on the entire surface of the electrode. Silver was labelled with the sup(110m)Ag isotope with a specific activity of 0.74 GBq/g Ag. The surface density values were determined autoradiographically. The mass transfer coefficients were calculated from autoradiogram optical densities and the surface density of the silver to be determined. It was found that mixing by nitrogen through a cullet was considerably nonhomogeneous; when the gas was distributed along the bottom the mixing was more homogeneous. (H.S.)

  5. High cost of stage IV pressure ulcers.

    Science.gov (United States)

    Brem, Harold; Maggi, Jason; Nierman, David; Rolnitzky, Linda; Bell, David; Rennert, Robert; Golinko, Michael; Yan, Alan; Lyder, Courtney; Vladeck, Bruce

    2010-10-01

    The aim of this study was to calculate and analyze the cost of treatment for stage IV pressure ulcers. A retrospective chart analysis of patients with stage IV pressure ulcers was conducted. Hospital records and treatment outcomes of these patients were followed up for a maximum of 29 months and analyzed. Costs directly related to the treatment of pressure ulcers and their associated complications were calculated. Nineteen patients with stage IV pressure ulcers (11 hospital-acquired and 8 community-acquired) were identified and their charts were reviewed. The average hospital treatment cost associated with stage IV pressure ulcers and related complications was $129,248 for hospital-acquired ulcers during 1 admission, and $124,327 for community-acquired ulcers over an average of 4 admissions. The costs incurred from stage IV pressure ulcers are much greater than previously estimated. Halting the progression of early stage pressure ulcers has the potential to eradicate enormous pain and suffering, save thousands of lives, and reduce health care expenditures by millions of dollars. Copyright © 2010 Elsevier Inc. All rights reserved.

  6. Direct complexonometric determination of thorium (IV), uranium (IV), neptunium (IV), plutonium (IV) by titration of diethylenetriaminepentaacetic acid with xylenol orange as indicator

    International Nuclear Information System (INIS)

    Rykov, A.G.; Piskunov, E.M.; Timofeev, G.A.

    1975-01-01

    The purpose of the present work was to develop a method of determining Th(IV), U(IV), Np(N) and Pu(IV) in acid solutions by titration with diethylenetriamine pentacetic acid, the indicator being xylenol orange. It has been established that Th, U, Np and Pu can be determined to within 0.5-1.5%. Th and U in quantities of tens of milligrams can be determined with greater accuracy, attaining hundredths of one per cent. During titration the determination is not hindered by singly- and doubly-charged metal ions, trivalent lanthanides and actinides, except plutonium. The proposed method can be used to determine U(IV) in the presence of considerable quantities of U(VI) and Np(IV) in the presence of Np(V). Total concentrations of uranium or neptunium are determined by reducing uranium (VI) or neptunium (V) by a standard method (for example, using metallic lead, cadmium or zinc amalgam) to the tetravalent state and applying the method described in the paper. (E.P.)

  7. Solubility studies of Np(IV)

    International Nuclear Information System (INIS)

    Zhang Yingjie; Yao Jun; Jiao Haiyang; Ren Lihong; Zhou Duo; Fan Xianhua

    2001-01-01

    The solubility of Np(IV) in simulated underground water and redistilled water has been measured with the variations of pH(6-12) and storage time (0-100 d) in the presence of reductant (Na 2 S 2 O 4 , metallic Fe). All experiments are performed in a low oxygen concentration glove box containing high purity Ar(99.99%), with an oxygen content of less than 5 x 10 -6 mol/mol. Experimental results show that the variation of pH in solution has little effect on the solubility of Np(IV) in the two kinds of water; the measured solubility of Np(IV) is affected by the composition of solution; with Na 2 S 2 O 4 as a reductant, the solubility of Np(IV) in simulated underground water is (9.23 +- 0.48) x 10 -10 mol/L, and that in redistilled water is (8.31 +- 0.35) x 10 -10 mol/L; with metallic Fe as a reductant, the solubility of Np(IV) in simulated underground water is (1.85 +- 0.56) x 10 -9 mol/L, and that in redistilled water is (1.48 +- 0.66) x 10 -9 mol/L

  8. Review on Korea Participation of Generation IV International Forum (GIF)

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jewhan; Jeong, Ji-Young; Hahn, Dohee [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-05-15

    Generation IV International Forum (GIF) originates from US proposal of an initiative in 2000. The vision was to leapfrog LWR technology and collaborate with international partners to share R and D on advanced nuclear systems. Nine countries and EU joined the initiative and Gen IV concept was defined via technology goals and legal framework. Two years study with more than 100 experts worldwide has evaluated nearly 100 reactor designs and down selected six most promising concepts. In 2005, the first signatures on Framework Agreement were collected and the first research projects were defined in 2006. Korea is one of the founding members of GIF and actively participating in various areas. In 2013, TD was assigned to Korean expert and Korea is endeavoring to enhance the benefit of participation since this turning point. In this paper, pros and cons of engaging with GIF were briefly introduced and items to maximize the benefit were suggested.

  9. Review on Korea Participation of Generation IV International Forum (GIF)

    International Nuclear Information System (INIS)

    Lee, Jewhan; Jeong, Ji-Young; Hahn, Dohee

    2015-01-01

    Generation IV International Forum (GIF) originates from US proposal of an initiative in 2000. The vision was to leapfrog LWR technology and collaborate with international partners to share R and D on advanced nuclear systems. Nine countries and EU joined the initiative and Gen IV concept was defined via technology goals and legal framework. Two years study with more than 100 experts worldwide has evaluated nearly 100 reactor designs and down selected six most promising concepts. In 2005, the first signatures on Framework Agreement were collected and the first research projects were defined in 2006. Korea is one of the founding members of GIF and actively participating in various areas. In 2013, TD was assigned to Korean expert and Korea is endeavoring to enhance the benefit of participation since this turning point. In this paper, pros and cons of engaging with GIF were briefly introduced and items to maximize the benefit were suggested

  10. Experimental facilities for Generation IV reactors research

    International Nuclear Information System (INIS)

    Krecanova, E.; Di Gabriele, F.; Berka, J.; Zychova, M.; Macak, J.; Vojacek, A.

    2013-06-01

    Centrum Vyzkumu Rez (CVR) is research and development Company situated in Czech Republic and member of the UJV group. One of its major fields is material research for Generation IV reactor concepts, especially supercritical water-cooled reactor (SCWR), very high temperature/gas-cooled fast reactor (VHTR/GFR) and lead-cooled fast reactor (LFR). The CVR is equipped by and is building unique experimental facilities which simulate the environment in the active zones of these reactor concepts and enable to pre-qualify and to select proper constructional materials for the most stressed components of the facility (cladding, vessel, piping). New infrastructure is founded within the Sustainable Energy project focused on implementation the Generation IV and fusion experimental facilities. The research of SCWR concept is divided to research and development of the constructional materials ensured by SuperCritical Water Loop (SCWL) and fuel components research on Fuel Qualification Test loop (SCWL-FQT). SCWL provides environment of the primary circuits of European SCWR, pressure 25 MPa, temperature 600 deg. C and its major purpose is to simulate behavior of the primary medium and candidate constructional materials. On-line monitoring system is included to collect the operational data relevant to experiment and its evaluation (pH, conductivity, chemical species concentration). SCWL-FQT is facility focused on the behavior of cladding material and fuel at the conditions of so-called preheater, the first pass of the medium through the fuel (in case of European SCWR concept). The conditions are 450 deg. C and 25 MPa. SCWL-FQT is unique facility enabling research of the shortened fuel rods. VHTR/GFR research covers material testing and also cleaning methods of the medium in primary circuit. The High Temperature Helium Loop (HTHL) enables exposure of materials and simulates the VHTR/GFR core environment to analyze the behavior of medium, especially in presence of organic compounds and

  11. Thiocyanato species of uranium(IV)

    International Nuclear Information System (INIS)

    Loyson, P.L.R.

    1974-12-01

    The aim of this thesis was to study the system U +4 /ClO 4 - /NCS - /HMPA/ - Solvent. This was done by means of various physical chemical methods. Spectrophotometric and conductometric evidence indicated that the following are the important species, which exist in acetone solution: (U(ClO 4 ) 3 .3acetone) + , (U(NCS) 3 .5acetone) + , (U 2 (NCS) 9 .6acetone) - , (U(NCS) 3 .2HMPA.3acetone) + , (U(NCS) 5 .2HMPA) - , (U(ClO 4 ) 3 .3HMPA) + , (U(NCS).5HMPA) +3 , (U(NCS) 2 .4HMPA) +2 and (U(NCS) 3 .3HMPA) + . The replacement of the large ClO 4 - ion by the much smaller NCS - anion results in a change in coordination of the U +4 , from six to eight. The formation of the species (U(NCS) 5 .2HMPA) - wasalso suggested by infrared studies and solubility determinations. The effect of a polar solvent on U(NCS) 4 .4HMPA was also studied, which indicated that, on solvation in methyl cyanide, U(NCS) 4 .4HMPA loses bound HMPA molecules. The ultimate goal of this project, i.e. the determination of the successive stability constants of the uranium(IV)thiocyanato complexes in acetone, was not reached, however, due to limitations of the computer program used. A qualitative treatment revealed that the stability of (U(NCS) 3 .5acetone) + , in acetone, is of the same order of magnitude as that of Co(NCS) 3 - ; similarly the species (U 2 (NCS) 9 .6acetone) - seems to be as stable as C0(NCS) 4 =. It was also indicated that excess U +4 cannot remove all bound NCS - from Co +2 . Finally the thiocyanato complexes of U +4 , relative to those of CO +2 , seem to be more stable in methyl cyanide, a N-donor solvent, than in acetone, an O-donor solvent

  12. Validation of practical notebook Morphophysiology IV

    Directory of Open Access Journals (Sweden)

    Rafael Capote Martínez

    2012-03-01

    Full Text Available Since the implementation of the Morphophysiology, 2007-2008 academic year, has shown a low achievement and motivation of students in individual and independent study. Most of them do not possess the skills or general intellectual development freelancing enough to assimilate the great independence required by this new learning model. Therefore, it was decided to introduce a new medium of instruction notebook handy morphophysiology IV which is an orientation guide for individual and independent study of students at the same time improves the management process of the educational process, whose usefulness is intended to validate. They surveyed 345 (94.8% who choose different specialties including Physical Culture. It was used in the survey, the questionnaire technique questions and answers, the closed first, and combining the direct and indirect, with some filter. This study was conducted through the comparison test of proportions between independent samples, using the Microstat statistical system, with a significance level of α = 0.05 (P <0.05. The 97.33% and 95.6% of students classified as necessary and useful respectively, the Practical Notebook, based on teaching assignments. The 67.84% of students suggests that the effectiveness of Practical Notebook is achieved when it is developed in a coordinated manner from staff student effort, reflections set out in groups or teams of study and the guiding role and facilitator professor, where it appears that forces develop participatory techniques. It is concluded that the Practical Notebook, acts as a methodological guide guiding, and developed through teaching assignments by students during individual and independent study, represents an effective tool for the learning process, contributing significantly to the improvement morphophysiology the curricular discipline.

  13. On the stabilization of niobium(V) solutions by zirconium(IV) and hafnium(IV)

    DEFF Research Database (Denmark)

    Sørensen, E.; Bjerre, A.B.

    1992-01-01

    Niobium cannot be separated from zirconium or hafnium when these elements occur together in solution with common anions such as chloride and sulphate. This is ascribed to the co-polymerization of niobium(V) and the hydrolysed ionic species of zirconium(IV) and hafnium(IV) to form colloidal...

  14. Complexation of the An(IV) by NTA; Complexation des An(IV) par le NTA

    Energy Technology Data Exchange (ETDEWEB)

    Bonin, L. [Paris-11 Univ., 91 - Orsay (France)]|[CEA Valrho, Lab. de Chimie des Actinides (LCA), 30 - Marcoule (France)

    2006-07-01

    In the framework of the Nuclear and Environmental Toxicology program, developed in France, it has been decided to take again the studies concerning the actinides decorporation. A similar study of the neptunium complexation by the citrate ions has been carried out on the complexation of Np(IV) with the nitrilotriacetic acid (NTA). The NTA can be considered as a model molecule of the de-corporating molecules (amino-carboxy- ligand). The results of the spectrophotometric measurements being encouraging, the behaviour of several actinides at the same oxidation state (+IV) (Th(IV), U(IV), Np(IV), and Pu(IV)) has been determined. The experimental results are presented. In order to determine the structure of the complexes of stoichiometry 1:2 An(IV)-(NTA){sub 2} in solution, quantic chemistry calculations and EXAFS measurements have been carried out in parallel. These studies confirm the presence of An(IV)-nitrogen bonds whose length decreases from thorium to plutonium and indicate the presence of a water molecule bound to the thorium and the uranium (coordination number 8 for Np/Pu, 9 for Th/U). The evolution of the complexation constants determined in this study in terms of 1/r (r ionic radius of the cation taking into account its coordination number 8 or 9) confirms the change of the coordination number between Th/U and Np/Pu. (O.M.)

  15. Transuranium perrhenates: Np(IV), Pu(IV) and (III), Am (III)

    International Nuclear Information System (INIS)

    Silvestre, Jean-Paul; Freundlich, William; Pages, Monique

    1977-01-01

    Synthesis in aqueous solution and by solid state reactions, crystallographical characterization and study of the stability of some transuranium perrhenates: Asup(n+)(ReO 4 - )sub(n) (A=Np(IV), Pu(IV), Pu(III), Am(III) [fr

  16. Oxochloroalkoxide of the Cerium (IV and Titanium (IV as oxides precursor

    Directory of Open Access Journals (Sweden)

    Machado Luiz Carlos

    2002-01-01

    Full Text Available The Cerium (IV and Titanium (IV oxides mixture (CeO2-3TiO2 was prepared by thermal treatment of the oxochloroisopropoxide of Cerium (IV and Titanium (IV. The chemical route utilizing the Cerium (III chloride alcoholic complex and Titanium (IV isopropoxide is presented. The compound Ce5Ti15Cl16O30 (iOPr4(OH-Et15 was characterized by elemental analysis, FTIR and TG/DTG. The X-ray diffraction patterns of the oxides resulting from the thermal decomposition of the precursor at 1000 degreesC for 36 h indicated the formation of cubic cerianite (a = 5.417Å and tetragonal rutile (a = 4.592Å and (c = 2.962 Å, with apparent crystallite sizes around 38 and 55nm, respectively.

  17. Spectroscopy and chemistry of uranium IV

    International Nuclear Information System (INIS)

    Folcher, G.; Rigny, P.

    1980-06-01

    Different fundamental research papers on uranium IV are presented, some were never edited. Molecular spectroscopy was used for identification and structural study of uranium IV in aqueous or organic solutions. The fields studied are: coordination, stereochemistry, electronic structure and chemical properties. For interpretation of results some studies were made with solid compounds or with thorium compounds or thorium complexes. Knowledge of actinides chemistry is improved, uranium and thorium being models for 5 f ions, extractive chemistry is better understood and new applications are possible [fr

  18. Vectorization at the KENO-IV code

    International Nuclear Information System (INIS)

    Asai, K.; Higuchi, K.; Katakura, J.

    1986-01-01

    The multigroup criticality safety code KENO-IV has been vectorized and tested on the FACOM VP-100 vector processor. At first, the vectorized KENO-IV on a scalar processor was slower than the original one by a factor of 1.4 because of the overhead introduced by vectorization. Making modifications of algorithms and techniques for vectorization, the vectorized version has become faster than the original one by a factor of 1.4 on the vector processor. For further speedup of the code, some improvements on compiler and hardware, especially on addition of Monte Carlo pipelines to the vector processor, are discussed

  19. Functions in Free-Format RPG IV

    CERN Document Server

    Martin, Jim

    2009-01-01

    Written especially for programmers adopting a free-format style, this manual explores the role of functions in writing RPG IV programs. Demonstrating the potential of functions, many topics are explored such as details about existing RPG IV built-in functions, writing new functions, using ILE concepts to use C functions, and utilizing IBM API's functions. Explaining how to write small programs, either as sub-procedures or modules, and how to gather those parts together to make programs that are easy to write and maintain, this is a natural next step for programmers familiar with a free-format

  20. Gen IV. Technical and economical aspects

    International Nuclear Information System (INIS)

    Kaluzny, Y.; Legee, F.

    2010-01-01

    In this presentation author deals with development of nuclear reactor type of Generation IV. He concluded that: - Nuclear energy is competitive with regards to the other generation sources; Its competitiveness also increases with CO 2 cost. Considering the nuclear cost breakdown of LWR reactors, it turns out that the uranium is currently not in the range of a threshold for FBR deployment; - The global balance of uranium supply and demand and also innovation required to fulfil GEN IV objectives would probably imply the emergence of fast reactor competitiveness after the turn of the mid-century; - We shall need fast reactors in the coming decade.

  1. Can children undergoing ophthalmologic examinations under anesthesia be safely anesthetized without using an IV line?

    Directory of Open Access Journals (Sweden)

    Vigoda M

    2011-04-01

    Full Text Available Michael M Vigoda, Azeema Latiff, Timothy G Murray, Jacqueline L Tutiven, Audina M Berrocal, Steven GayerBascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USAPurpose: To document that with proper patient and procedure selection, children undergoing general inhalational anesthesia for ophthalmologic exams (with or without photos, ultrasound, laser treatment, peri-ocular injection of chemotherapy, suture removal, and/or replacement of ocular prosthesis can be safely anesthetized without the use of an intravenous (IV line. Children are rarely anesthetized without IV access placement. We performed a retrospective study to determine our incidence of IV access placement during examinations under anesthesia (EUA and the incidence of adverse events that required intraoperative IV access placement.Methods: Data collected from our operating room (OR information system includes but is not limited to diagnosis, anesthesiologist, surgeon, and location of IV catheter (if applicable, patient’s date of birth, actual procedure, and anesthesia/procedure times. We reviewed the OR and anesthetic records of children (>1 month and <10 years who underwent EUAs between January 1, 2003 and May 31, 2009. We determined the percentage of children who were anesthetized without IV access placement, as well as the incidence of any adverse events that required IV access placement, intraoperatively.Results: We analyzed data from 3196 procedures performed during a 77-month period. Patients’ ages ranged from 1 month to 9 years. Overall, 92% of procedures were performed without IV access placement. Procedure duration ranged from 1–39 minutes. Reasons for IV access placement included parental preference for antinausea medication and/or attending preference for IV access placement. No child who underwent anesthesia without an IV line had an intraoperative adverse event requiring insertion of an IV line.Conclusion: Our data suggest that for

  2. sA Comparison of DSM-IV-TR and DSM-5 Diagnostic Classifications in the Clinical Diagnosis of Autistic Spectrum Disorder

    Science.gov (United States)

    Yaylaci, Ferhat; Miral, Suha

    2017-01-01

    Aim of this study was to compare children diagnosed with Pervasive Developmental Disorder (PDD) according to DSM-IV-TR and DSM-5 diagnostic systems. One hundred fifty children aged between 3 and 15 years diagnosed with PDD by DSM-IV-TR were included. PDD symptoms were reviewed through psychiatric assessment based on DSM-IV-TR and DSM-5 criteria.…

  3. Meeting of the Task Force 'Information Systems in Soil Science', Freising-Weihenstephan, March 20-21, 1986. - Joint meeting of the Commissions V and VI, Osnabrueck, February 17-18, 1987. - Joint meeting of the Commissions I and IV, Bayreuth, April 23-24, 1987. Papers. Treffen der Arbeitsgruppe Informationssysteme in der Bodenkunde, 20. und 21. Maerz 1986, Freising-Weihenstephan. - Gemeinsame Sitzung der Kommissionen V und VI, 17. und 18. Februar 1987, Osnabrueck. - Gemeinsame Sitzung der Kommissionen I und IV, 23. und 24. April 1987, Bayreuth. Referate

    Energy Technology Data Exchange (ETDEWEB)

    1987-01-01

    This volume contains 9 contributions of the Task Force 'Information Systems in Soil Science' (meeting at Freising-Weihenstephan from March 20-21, 1986), 49 papers of Commissions V and VI (meeting at Osnabrueck from February 17-18, 1987), and 17 papers of Commissions I and IV (meeting at Bayreuth from April 23-24, 1987). From the subject areas 'Heavy Metal Pollution of Soils' and 'Land Revegetation after Construction of District Heat Pipelines', six contributions have been separately recorded in the ENERGY data base.

  4. Neutron lifetime and generation time by KENO IV

    International Nuclear Information System (INIS)

    Hayashi, Masatoshi

    1991-01-01

    It is believed that Monte Carlo method is suitable to the calculation of neutron lifetime and generation time with reference to the life cycle viewpoint. This paper illustrates that those times obtained by Monte Carlo method are quite different from the results by perturbation method. The neutron lifetime and the generation time for bare and reflected reactors were investigated by the Monte Carlo program, KENO IV. the Monte Carlo procedure is based on tracking and recording the life history of neutrons in a realistic fashion in a fissionable system with minimum nuclear and geometric approximations. The KENO IV provides the multiplication factor, neutron lifetime and generation time simultaneously. The thermal spherical reactors for both bare and reflected reactors were studied using the KENO IV. The reflected reactor is surrounded with 30 cm thick light water. The atomic densities in the regions and the calculated results of the multiplication factor, neutron lifetime and generation time are given. The different definitions of these times between the Monte Carlo method and perturbation theory caused the difference of the results. (K.I.)

  5. KENO IV: an improved Monte Carlo criticality program

    International Nuclear Information System (INIS)

    Petrie, L.M.; Cross, N.F.

    1975-11-01

    KENO IV is a multigroup Monte Carlo criticality program written for the IBM 360 computers. It executes rapidly and is flexibly dimensioned so the allowed size of a problem (i.e., the number of energy groups, number of geometry cards, etc., are arbitrary) is limited only by the total data storage required. The input data, with the exception of cross sections, fission spectra and albedos, may be entered in free form. The geometry input is quite simple to prepare and complicated three-dimensional systems can often be described with a minimum of effort. The results calculated by KENO IV include k-effective, lifetime and generation time, energy-dependent leakages and absorptions, energy- and region-dependent fluxes and region-dependent fission densities. Criticality searches can be made on unit dimensions or on the number of units in an array. A summary of the theory utilized by KENO IV, a section describing the logical program flow, a compilation of the error messages printed by the code and a comprehensive data guide for preparing input to the code are presented. 14 references

  6. Bis(4-methylpiperidinium hexachloridostannate(IV

    Directory of Open Access Journals (Sweden)

    Madeleine Helliwell

    2008-04-01

    Full Text Available The crystal structure of the title compound, (C6H14N2[SnCl6], is built of 4-methylpiperidinium cations, occupying special positions on the mirror plane, and hexachloridostannate(IV anions on a special position of 2/m symmetry. The ions are linked via N—H...Cl hydrogen bonds into chains running along the b axis.

  7. Resonance transition array of Yb IV

    International Nuclear Information System (INIS)

    Kaufman, V.; Sugar, J.

    1976-01-01

    Nineteen pairs of lines in the wavelength range of 800--1300 A were identified as transitions to the two levels of the ground term of Yb IV, 4f 13 2 F. The 2 F 5 / 2 -- 2 F 7 / 2 interval is 10 214.0 cm -1 with an rms deviation of 0.4 cm -1

  8. IV-DSA of vertigo patients

    International Nuclear Information System (INIS)

    Watanabe, Hiromi; Ito, Masatoshi; Takita, Kimio; Matsuzawa, Taiju.

    1988-01-01

    With IV-DSA(Intra-Venous Digital Subtraction Angiography), we examined the relations between vertigo or dizziness and asymmetries of cervical vertebral arteries. In this time, as the asymmetries we chose next three; hemi-stenosis, hemi-occulusion and hemi-strong tortuosity. In the appearance of the asymmetries, there was no differance between those who complain vertigo or dizziness and others. (author)

  9. National Coastal Condition Report IV (2012)

    Science.gov (United States)

    The NCCR IV data shows an overall condition score of 3.0 for the nation’s coastal waters; although this score has improved substantially since 1990, the overall condition of the nation’s coastal resources continues to be rated fair.

  10. Coordination and solvent extraction behaviour of oxozirconium(IV), thorium(IV) and dioxouranium(VI)

    International Nuclear Information System (INIS)

    Dash, K.C.

    1989-01-01

    The systematic liquid-liquid extraction behaviour of oxozirconium (IV), thorium(IV) and dioxouranium(VI) have been investigated using a number of synthesised and commercial chelating extractants. The synergism or antagonism for these processes in presence of neutral donor ligands have also been identified and the conditions for separation and isolation of pure individual metal ions have been established. The coordination behaviour of oxozirconium(IV), thorium(IV) and dioxouranium(VI) with a large number of mono- and polydentate ligands have been studied. With oxozirconium(IV), invariably always a cyclic, tetranuclear species is obtained, derived from the tetrameric structure of the parent ZrOCl 2 .8H 2 O which is actually (Zr 4 (OH) 8 (H 2 O) 16 )Cl 8 .12H 2 O. No simple, monomeric oxozirconium(IV) complex was obtained. Uranium(VI) and thorium(IV) form a wide variety of complexes of higher coordination numbers and several bi- and trinuclear complexes were also characterised where the two adjacent metal centres are joined to each other by a double hydroxo-bridge. (author). 69 refs., 3 figs., 4 tabs

  11. Ehlers-Danlos syndrome type IV

    Directory of Open Access Journals (Sweden)

    Germain Dominique P

    2007-07-01

    Full Text Available Abstract Ehlers-Danlos syndrome type IV, the vascular type of Ehlers-Danlos syndromes (EDS, is an inherited connective tissue disorder defined by characteristic facial features (acrogeria in most patients, translucent skin with highly visible subcutaneous vessels on the trunk and lower back, easy bruising, and severe arterial, digestive and uterine complications, which are rarely, if at all, observed in the other forms of EDS. The estimated prevalence for all EDS varies between 1/10,000 and 1/25,000, EDS type IV representing approximately 5 to 10% of cases. The vascular complications may affect all anatomical areas, with a tendency toward arteries of large and medium diameter. Dissections of the vertebral arteries and the carotids in their extra- and intra-cranial segments (carotid-cavernous fistulae are typical. There is a high risk of recurrent colonic perforations. Pregnancy increases the likelihood of a uterine or vascular rupture. EDS type IV is inherited as an autosomal dominant trait that is caused by mutations in the COL3A1 gene coding for type III procollagen. Diagnosis is based on clinical signs, non-invasive imaging, and the identification of a mutation of the COL3A1 gene. In childhood, coagulation disorders and Silverman's syndrome are the main differential diagnoses; in adulthood, the differential diagnosis includes other Ehlers-Danlos syndromes, Marfan syndrome and Loeys-Dietz syndrome. Prenatal diagnosis can be considered in families where the mutation is known. Choriocentesis or amniocentesis, however, may entail risk for the pregnant woman. In the absence of specific treatment for EDS type IV, medical intervention should be focused on symptomatic treatment and prophylactic measures. Arterial, digestive or uterine complications require immediate hospitalisation, observation in an intensive care unit. Invasive imaging techniques are contraindicated. Conservative approach is usually recommended when caring for a vascular

  12. Ehlers-Danlos syndrome type IV

    Science.gov (United States)

    Germain, Dominique P

    2007-01-01

    Ehlers-Danlos syndrome type IV, the vascular type of Ehlers-Danlos syndromes (EDS), is an inherited connective tissue disorder defined by characteristic facial features (acrogeria) in most patients, translucent skin with highly visible subcutaneous vessels on the trunk and lower back, easy bruising, and severe arterial, digestive and uterine complications, which are rarely, if at all, observed in the other forms of EDS. The estimated prevalence for all EDS varies between 1/10,000 and 1/25,000, EDS type IV representing approximately 5 to 10% of cases. The vascular complications may affect all anatomical areas, with a tendency toward arteries of large and medium diameter. Dissections of the vertebral arteries and the carotids in their extra- and intra-cranial segments (carotid-cavernous fistulae) are typical. There is a high risk of recurrent colonic perforations. Pregnancy increases the likelihood of a uterine or vascular rupture. EDS type IV is inherited as an autosomal dominant trait that is caused by mutations in the COL3A1 gene coding for type III procollagen. Diagnosis is based on clinical signs, non-invasive imaging, and the identification of a mutation of the COL3A1 gene. In childhood, coagulation disorders and Silverman's syndrome are the main differential diagnoses; in adulthood, the differential diagnosis includes other Ehlers-Danlos syndromes, Marfan syndrome and Loeys-Dietz syndrome. Prenatal diagnosis can be considered in families where the mutation is known. Choriocentesis or amniocentesis, however, may entail risk for the pregnant woman. In the absence of specific treatment for EDS type IV, medical intervention should be focused on symptomatic treatment and prophylactic measures. Arterial, digestive or uterine complications require immediate hospitalisation, observation in an intensive care unit. Invasive imaging techniques are contraindicated. Conservative approach is usually recommended when caring for a vascular complication in a patient suffering

  13. Structural organization and spectroscopy of peptide-actinide(IV) complexes

    International Nuclear Information System (INIS)

    Dahou, S.

    2010-01-01

    The contamination of living organisms by actinide elements is at the origin of both radiological and chemical toxicity that may lead to severe dysfunction. Most of the data available on the actinide interaction with biological systems are macroscopic physiological measurements and are lacking a molecular description of the systems. Because of the intricacy of these systems, classical biochemical methods are difficult to implement. Our strategy consisted in designing simplified biomimetic peptides, and describing the corresponding intramolecular interactions with actinides. A carboxylic pentapeptide of the form DDPDD has been at the starting point of this work in order to further assess the influence of the peptide sequence on the topology of the complexes.To do so, various linear (Asp/Ala permutations, peptoids) and cyclic analogues have been synthesized. Furthermore, in order to include the hydroxamic function (with a high affinity for Fe(III)) in the peptide, both desferrioxamine and acetohydroxamic acid have been investigated. However because of difficulties in synthesis, we have not been able to test these peptides. Three actinide cations have been considered at oxidation state +IV (Th, Np, Pu) and compared to Fe(III), often considered as a biological surrogate of Pu(IV). The spatial arrangement of the peptide around the cation has been probed by spectrophotometry and X-ray Absorption Spectroscopy. The spectroscopic data and EXAFS data adjustment lead us to rationalize the topology of the complexes as a function of the peptide sequence: mix hydroxy polynuclear species for linear and cyclic peptides, mononuclear for the desferrioxamine complexes. Furthermore, significant differences have appeared between Fe(III) and actinide(IV), related to differences of reactivity in aqueous medium. (author)

  14. European project SARGEN IV: safety approach and assessment of GEN IV reactors

    International Nuclear Information System (INIS)

    Ammirabile, L.

    2013-01-01

    • SARGEN I V has elaborated a proposal for the harmonization of safety assessment practices for GEN IV NPP. • An overall reinforcement of DiD is expected for GEN I V NPP, including improved independence between all levels of DiD. • An inherent approach should reinforce the fulfillment of fundamental safety functions e.g. the consequences for some situations should be reduced and the grace periods should be extended. For the same reason, the use of passive systems can be envisaged. • The need of complementary and integrated deterministic and probabilistic approaches is reiterated. • Methodologies: Some of them are not yet applied. • Assessment of hazards would be a challenging aspect of next generation of NPP safety assessment and should be improved, which is confirmed by the first insights of Fukushima Daiichi TEPCO reactors accidents. • Provisions to cope with extreme events notably to improve the grace period before cliff-edge effects and thus allowing back-up measures to be implemented have to be defined and should be considered as hardened equipments

  15. Prospective Evaluation of the Safety and Efficacy of a 1060-nm Large Spot Size, Vacuum-Assisted Hair Removal Diode Laser System in Asian/Pacific Fitzpatrick's Skin Types IV-V Patients.

    Science.gov (United States)

    Tahiliani, Sushil T; Tahiliani, Harsh S

    2016-11-01

    Laser-based photoepilation of dark skin types demands a delicate combination of appropriate light wavelengths and spot size to achieve optimal epidermal-to-follicular energy absorption ratios. This prospective study assessed the axillary, arm, thigh, and back hair clearing ef cacy of the LightSheer In nity 1060 nm diode laser in 10 Fitzpatrick skin type IV-V patients. Each area was treated up to ve times, at 4-6-week intervals, after which immediate skin responses and adverse events were recorded. Hair count, color and coarseness were assessed before each treatment session, as well as 1, 3, and 6 months following the last session. Both patients and the treating physician rated the degree of improvement with time, and patients also ranked their satisfaction with the treatment outcome. Percent hair reduction from baseline gradually increased with treatment and peaked at 74.6%, 68.4%, and 65.7% for axillary, arm and thigh regions, respectively, 6 months following the last treatment session. Baseline hair growth patterns precluded effective selection of a representative area for hair counting. Patients satisfaction was consistently higher for axillary hair clearance rates, followed by thigh and arm responses. Throughout the follow-up period, the investigator rated 50-67% of the treated axillae as presenting "good" or "very good" hair clearance, and provided similar ratings for 67% of the treated thigh regions at both the 1 and 6 month follow-up sessions. Immediate responses to treatment were mild to moderate and short-lived and no incidents of brosis or scarring were reported. Taken together, the LightSheer In nity 1060 HS Handpiece provided for an ideal ef cacy-safety balance in treating dark-skinned patients, providing for long-term hair clearance with minimal downtime. J Drugs Dermatol. 2016;15(11):1427-1434.

  16. Identification of novel dipeptidyl peptidase IV (DPP-IV) inhibitory peptides in camel milk protein hydrolysates.

    Science.gov (United States)

    Nongonierma, Alice B; Paolella, Sara; Mudgil, Priti; Maqsood, Sajid; FitzGerald, Richard J

    2018-04-01

    Nine novel dipeptidyl peptidase IV (DPP-IV) inhibitory peptides (FLQY, FQLGASPY, ILDKEGIDY, ILELA, LLQLEAIR, LPVP, LQALHQGQIV, MPVQA and SPVVPF) were identified in camel milk proteins hydrolysed with trypsin. This was achieved using a sequential approach combining liquid chromatography tandem mass spectrometry (LC-MS/MS), qualitative/quantitative structure activity relationship (QSAR) and confirmatory studies with synthetic peptides. The most potent camel milk protein-derived DPP-IV inhibitory peptides, LPVP and MPVQA, had DPP-IV half maximal inhibitory concentrations (IC 50 ) of 87.0 ± 3.2 and 93.3 ± 8.0 µM, respectively. DPP-IV inhibitory peptide sequences identified within camel and bovine milk protein hydrolysates generated under the same hydrolysis conditions differ. This was linked to differences in enzyme selectivity for peptide bond cleavage of camel and bovine milk proteins as well as dissimilarities in their amino acid sequences. Camel milk proteins contain novel DPP-IV inhibitory peptides which may play a role in the regulation of glycaemia in humans. Copyright © 2017 Elsevier Ltd. All rights reserved.

  17. O pessegueiro no sistema de pomar compacto: IV. Intensidade e época de raleio dos frutos dos cultivares Tropical e Aurora-1 The peach meadow orchard system: IV. Intensity and time of hand fruit thinning of Tropical and Aurora-1 cultivars

    Directory of Open Access Journals (Sweden)

    Wilson Barbosa

    1991-01-01

    Full Text Available A intensidade e a época do raleio dos frutos do pessegueiro podem influenciar diretamente a qualidade do produto, razão pela qual foram pesquisadas em um pomar compacto (4.167 plantas por hectare, sob poda drástica anual de renovação da copa. O experimento foi executado na Estação Experimental de Jundiaí (23°08'S e 46°55'W, do Instituto Agronômico (IAC, sob clima do tipo Cwa, mesotérmico úmido, também denominado de tropical de altitude, com cerca de 80 horas anuais de frio abaixo de 7°C. Utílizaram-se os cultivares Tropical, de maturação bem precoce (fins de setembro, e Aurora-1, de maturação precoce (meados de outubro. Efetuou-se o raleio com 30, 40 e 50 dias pós-antese (DPA, deixando-se 30, 60 e 90 frutos por planta. Os melhores resultados, reunindo fatores qualitativos e quantitativos, foram obtidos no raleio aos 30 DPA, mantendo-se 60 frutos por planta. Neste tratamento, o 'Tropical' apresentou frutos com peso médio de 60,9 gramas, o que equivale à produção de 3,654kg/planta (15,2t/ha; com o 'Aurora-1', o peso médio dos frutos foi de 72,0 gramas, correspondendo à produção de 4,320kg/planta (18,0t/ha. Aqualidade final do produto diminuiu à medida que se atrasou a época do raleio e, principalmente, quando se manteve maior quantidade de frutos por planta. O 'Tropical' adaptou-se melhor ao sistema de pomar compacto: floresceu no 9° mês e seus frutos amadureceram no 12ª mês após a poda drástica da copa.The effect of intensity and time of hand thinning on the mean fruit weight and productivity was studied on 'Tropical' and 'Aurora-V peaches. The trees were cultivated under the meadow orchard system, 4,167 plants per hectare, with drastic pruning. The experimental plot was located at the Estação Experimental of Jundiaí (23°08'S and 46°55W of the Instituto Agronômico of Campinas, State of São Paulo, Brazil, with 80 tours per year of temperature below 7°C. The time of hand thinning was 30, 40 and 50 days

  18. IRIS Responsiveness to Generation IV Road-map Goals

    International Nuclear Information System (INIS)

    Carelli, M.D.; Paramonov, D.V.; Petrovic, B.

    2002-01-01

    The DOE Generation IV road-map process is in its second and final year. Almost one hundred concepts submitted from all over the world have been reviewed against the Generation IV goals of resources sustainability; safety and reliability; and, economics. Advanced LWRs are taken as the reference point. IRIS (International Reactor Innovative and Secure), a 100-335 MWe integral light water reactor being developed by a vast international consortium led by Westinghouse, is one on the concepts being considered in the road-map and is perhaps the most visible representative of the concept set known as Integral Primary System Reactors (IPSR). This paper presents how IRIS satisfies the prescribed goals. The first goal of resource sustainability includes criteria like utilization of fuel resources, amount and toxicity of waste produced, environmental impact, proliferation and sabotage resistance. As a thermal reactor IRIS does not have the same fuel utilization as fast reactors. However, it has a significant flexibility in fuel cycles as it is designed to utilize either UO 2 or MOX with straight burn cycles of 4 to 10 years, depending on the fissile content. High discharge burnup and Pu recycling result in good fuel utilization and lower waste; IRIS has also attractive proliferation resistance characteristics, due to the reduced accessibility of the fuel. The safety and reliability goal include reliability, workers' exposure, robust safety features, models with well characterized uncertainty, source term and mechanisms of energy release, robust mitigation of accidents. IRIS is significantly better than advanced LWRs because of its safety by design which eliminates a variety of accidents such as LOCAs, its containment vessel coupled design which maintains the core safely covered during the accident sequences, its design simplification features such as no (or reduced) soluble boron, internal shielding and four-year refueling/maintenance interval which significantly reduce

  19. Measurement of the power trasient and valve closing time, for the zone control system, during a programmed shutdown in August 1989 and its relation with the class IV partial loss event occurred on 27/12/88 in CNE (Embalse nuclear power plant)

    International Nuclear Information System (INIS)

    Paz, A.O. de; Moreno, C.A.; Vinez, J.C.

    1990-01-01

    A description is made of a number of measurements performed during the programmed shutdown on Embalse nuclear power plant (CNE) (August 1989) to validate the existance of a reactivity insertion owing to the emptying of the liquid zone control system. In the event occurred on 27/12/88 when there was a partial loss Cl IV. Once the existance of this contribution was confirmed, the pertinent corrective measures were taken and the test was repeated to verify the effectiveness of the latter. The temporal evolution of a number of neutronic variables and process variables of the liquid zone system were stored in an IBM-PC XT equipped with analog-to-digital converters, for later analysis. (Author) [es

  20. DSM-IV hypochondriasis in primary care.

    Science.gov (United States)

    Escobar, J I; Gara, M; Waitzkin, H; Silver, R C; Holman, A; Compton, W

    1998-05-01

    The object of this study was to assess the prevalence and correlates of the DSM-IV diagnosis of hypochondriasis in a primary care setting. A large sample (N = 1456) of primary care users was given a structured interview to make diagnoses of mood, anxiety, and somatoform disorders and estimate levels of disability. The prevalence of hypochondriasis (DSM-IV) was about 3%. Patients with this disorder had higher levels of medically unexplained symptoms (abridged somatization) and were more impaired in their physical functioning than patients without the disorder. Of the various psychopathologies examined, major depressive syndromes were the most frequent among patients with hypochondriasis. Interestingly, unlike somatization disorder, hypochondriasis was not related to any demographic factor. Hypochondriasis is a relatively rare condition in primary care that is largely separable from somatization disorder but seems closely intertwined with the more severe depressive syndromes.