WorldWideScience

Sample records for platforms supporting strain

  1. Cyber infrastructure for Fusarium: three integrated platforms supporting strain identification, phylogenetics, comparative genomics and knowledge sharing.

    Science.gov (United States)

    Park, Bongsoo; Park, Jongsun; Cheong, Kyeong-Chae; Choi, Jaeyoung; Jung, Kyongyong; Kim, Donghan; Lee, Yong-Hwan; Ward, Todd J; O'Donnell, Kerry; Geiser, David M; Kang, Seogchan

    2011-01-01

    The fungal genus Fusarium includes many plant and/or animal pathogenic species and produces diverse toxins. Although accurate species identification is critical for managing such threats, it is difficult to identify Fusarium morphologically. Fortunately, extensive molecular phylogenetic studies, founded on well-preserved culture collections, have established a robust foundation for Fusarium classification. Genomes of four Fusarium species have been published with more being currently sequenced. The Cyber infrastructure for Fusarium (CiF; http://www.fusariumdb.org/) was built to support archiving and utilization of rapidly increasing data and knowledge and consists of Fusarium-ID, Fusarium Comparative Genomics Platform (FCGP) and Fusarium Community Platform (FCP). The Fusarium-ID archives phylogenetic marker sequences from most known species along with information associated with characterized isolates and supports strain identification and phylogenetic analyses. The FCGP currently archives five genomes from four species. Besides supporting genome browsing and analysis, the FCGP presents computed characteristics of multiple gene families and functional groups. The Cart/Favorite function allows users to collect sequences from Fusarium-ID and the FCGP and analyze them later using multiple tools without requiring repeated copying-and-pasting of sequences. The FCP is designed to serve as an online community forum for sharing and preserving accumulated experience and knowledge to support future research and education.

  2. Cyber infrastructure for Fusarium: three integrated platforms supporting strain identification, phylogenetics, comparative genomics and knowledge sharing

    Science.gov (United States)

    Park, Bongsoo; Park, Jongsun; Cheong, Kyeong-Chae; Choi, Jaeyoung; Jung, Kyongyong; Kim, Donghan; Lee, Yong-Hwan; Ward, Todd J.; O'Donnell, Kerry; Geiser, David M.; Kang, Seogchan

    2011-01-01

    The fungal genus Fusarium includes many plant and/or animal pathogenic species and produces diverse toxins. Although accurate species identification is critical for managing such threats, it is difficult to identify Fusarium morphologically. Fortunately, extensive molecular phylogenetic studies, founded on well-preserved culture collections, have established a robust foundation for Fusarium classification. Genomes of four Fusarium species have been published with more being currently sequenced. The Cyber infrastructure for Fusarium (CiF; http://www.fusariumdb.org/) was built to support archiving and utilization of rapidly increasing data and knowledge and consists of Fusarium-ID, Fusarium Comparative Genomics Platform (FCGP) and Fusarium Community Platform (FCP). The Fusarium-ID archives phylogenetic marker sequences from most known species along with information associated with characterized isolates and supports strain identification and phylogenetic analyses. The FCGP currently archives five genomes from four species. Besides supporting genome browsing and analysis, the FCGP presents computed characteristics of multiple gene families and functional groups. The Cart/Favorite function allows users to collect sequences from Fusarium-ID and the FCGP and analyze them later using multiple tools without requiring repeated copying-and-pasting of sequences. The FCP is designed to serve as an online community forum for sharing and preserving accumulated experience and knowledge to support future research and education. PMID:21087991

  3. Development of Industrial Yeast Platform Strains

    DEFF Research Database (Denmark)

    Bergdahl, Basti; Dato, Laura; Förster, Jochen

    2014-01-01

    frequently encounter high substrate concentrations, low pH, high temperatures and various inhibitory compounds originating either from the raw material used or from cellular metabolism. The aim of this research project is to develop robust platform strains of Saccharomyces cerevisiae based on industrial...

  4. Platform decisions supported by gaming

    DEFF Research Database (Denmark)

    Hansen, Poul H. Kyvsgård; Mikkola, Juliana Hsuan

    2007-01-01

    Platform is an ambiguous multidisciplinary concept. The philosophy behind it is easy to communicate and makes intuitively sense. However, the ease in communication does overshadow the high complexity when the concept is implemented. The practical industrial platform implementation challenge can...... is the application of on-line games in order to provide training for decision makers and in order to generate overview over the implications of platform decisions. However, games have to be placed in a context with other methods and we argue that a mixture of games, workshops, and simulations can provide improved...

  5. A Platform to Support the Product Servitization

    Directory of Open Access Journals (Sweden)

    Giovanni Di Orio

    2016-02-01

    Full Text Available Nowadays manufacturers are forced to shift from their traditional product-manufacturing paradigm to the goods-services continuum by providing integrated combination of products and services. The adoption of service-based strategies is the natural consequence of the higher pressure that these companies are facing in the global markets especially due to the presence of competitors which operate in low wage region. By betting on services, or more specifically, on servitization manufacturing companies are moving up the value chain in order to move the competition from costs to sophistication and innovation. The proliferation of new emerging technologies and paradigms together with a wider dissemination of information technology (IT can significantly improve the capability of manufacturing companies to infuse services in their own products. The authors present a knowledge-based and data-driven platform that can support the design and development of Product Extended by Services (PESs solutions.

  6. Towards a metabolic engineering strain "commons": an Escherichia coli platform strain for ethanol production.

    Science.gov (United States)

    Woodruff, Lauren B A; May, Brian L; Warner, Joseph R; Gill, Ryan T

    2013-05-01

    In the genome-engineering era, it is increasingly important that researchers have access to a common set of platform strains that can serve as debugged production chassis and the basis for applying new metabolic engineering strategies for modeling and characterizing flux, engineering complex traits, and optimizing overall performance. Here, we describe such a platform strain of E. coli engineered for ethanol production. Starting with a fully characterized host strain (BW25113), we site-specifically integrated the genes required for homoethanol production under the control of a strong inducible promoter into the genome and deleted the genes encoding four enzymes from competing pathways. This strain is capable of producing >30 g/L of ethanol in minimal media with production or tolerance was lost when grown under production conditions. Thus, our findings reinforce the need for a metabolic engineering "commons" that could provide a set of platform strains for use in more sophisticated genome-engineering strategies. Towards this end, we have made this production strain available to the scientific community.

  7. Proposed teleworking platform for workstations supporting multimedia medical applications

    Science.gov (United States)

    Orphanos, George; Kanellopoulos, Dimitris; Prentzas, Lambros; Koubias, Stavros

    1993-09-01

    Teleworking refers to the usage of telecommunication facilities to improve human to human collaboration and enhance performance of work. This paper focuses on the way teleworking affects medicine. In particular, a teleworking platform is proposed to support multimedia medical applications embedded into RISC-based workstations. In order to support the teleworking platform, current commercially available products have to be taken into consideration and a range of new technologies need to be developed and made available. In this paper, we put emphasis on a RISC-based workstation, UNIXTM operating system, communication protocols capable to support the teleworking platform, and ISDN network capabilities.

  8. Composite support column assembly for offshore drilling and production platforms

    Energy Technology Data Exchange (ETDEWEB)

    Pierce, R.H.

    1989-04-18

    This patent describes a support column assembly for an offshore drilling and/or production comprising: means for anchoring the column assembly on the seabed; an elongated cylindrical support column including at least one generally cylindrical column member having a cylindrical wall formed of a composite of elongated filaments of at least one of carbon and boron bonded in a resin matrix, the support column including a plurality of the column members coupled end to end by coupling means at opposite ends of the column members, the coupling means including a plurality of radially project pins for coupling the composite wall to a coupling member interposed between the column members, respectively; and means for connecting the column to a platform for transmitting platform loads between the platform and the anchor means.

  9. Multimedia Content Management Support in Next Generation Service Platforms

    NARCIS (Netherlands)

    Spedalieri, A.; Sisto, G.; Cesar Garcia, P.S.; Melpignano, D.; Sinfreu, A.; Vaishnavi, I.

    2007-01-01

    The aim of this paper is to illustrate the architecture for multimedia content management support in new generation service platforms. The outlined architecture is based on the requirements identified by a set of interviews with experts from the media industry. According to the results of the interv

  10. Building Spatiotemporal Cloud Platform for Supporting GIS Application

    Science.gov (United States)

    Song, W. W.; Jin, B. X.; Li, S. H.; Wei, X. Y.; Li, D.; Hu, F.

    2015-07-01

    Traditional geospatial information platforms are built, managed and maintained by the geoinformation agencies. They integrate various geospatial data (such as DLG, DOM, DEM, gazetteers, and thematic data) to provide data analysis services for supporting government decision making. In the era of big data, it is challenging to address the data- and computing- intensive issues by traditional platforms. In this research, we propose to build a spatiotemporal cloud platform, which uses HDFS for managing image data, and MapReduce-based computing service and workflow for high performance geospatial analysis, as well as optimizing auto-scaling algorithms for Web client users' quick access and visualization. Finally, we demonstrate the feasibility by several GIS application cases.

  11. BUILDING SPATIOTEMPORAL CLOUD PLATFORM FOR SUPPORTING GIS APPLICATION

    Directory of Open Access Journals (Sweden)

    W. W. Song

    2015-07-01

    Full Text Available Traditional geospatial information platforms are built, managed and maintained by the geoinformation agencies. They integrate various geospatial data (such as DLG, DOM, DEM, gazetteers, and thematic data to provide data analysis services for supporting government decision making. In the era of big data, it is challenging to address the data- and computing- intensive issues by traditional platforms. In this research, we propose to build a spatiotemporal cloud platform, which uses HDFS for managing image data, and MapReduce-based computing service and workflow for high performance geospatial analysis, as well as optimizing auto-scaling algorithms for Web client users’ quick access and visualization. Finally, we demonstrate the feasibility by several GIS application cases.

  12. Social relations: network, support and relational strain

    DEFF Research Database (Denmark)

    Due, P; Holstein, B; Lund, Rikke

    1999-01-01

    ,011. The postal questionnaires were answered by a random sample in each of the age groups. The results show marked age and gender differences in both the structure and the function of social relations. The social network, measured as weekly contacts, weakens with age and so does instrumental support. Emotional......We introduce a conceptual framework with social relations as the main concept and the structure and the function of social relations as subconcepts. The structure of social relations covers aspects of formal relations and social network. The function of social relations covers social support......, social anchorage and relational strain. We use this conceptual framework to describe social relations in the Danish population, with questionnaire data from the Danish Longitudinal Health Behaviour Study including a random sample of each of the age groups 25-, 50-, 60-and 70-year olds, N = 2...

  13. A remote care platform for the social support program CASSAUDEC

    Directory of Open Access Journals (Sweden)

    Andrés Felipe Ardila Rodríguez

    2016-06-01

    Full Text Available The training strategies developed for the social support program bring deficits in accessibility to the chronic ill patients (EC and the CASSA-UDEC’s caretaker (CASSA-UDEC: Centre for Social Health Care at Universidad de Cundinamarca they do not have time to commute, hindering their legal relationship established by the contract. For this reason, a remote care platform (PTD was developed to support users at CASSA-UDEC improving aspects related to coverage, cost, quality, access and appropriation of information from caregivers and chronic ill patients. The design was based on gerontological constructs identifying features such as modularity, object size, usability, ergonomics, and some others, providing a friendly platform for the user with dynamic, modular and high usability content. The Platform provides a space for interaction and aid, which works as a dynamic entity in the job done by CASSA-UDEC giving support in the development of activities, expanding its coverage, access; all thanks to the benefits offered in a virtual mode.

  14. Measurement Uncertainty Analysis of the Strain Gauge Based Stabilographic Platform

    Directory of Open Access Journals (Sweden)

    Walendziuk Wojciech

    2014-08-01

    Full Text Available The present article describes constructing a stabilographic platform which records a standing patient’s deflection from their point of balance. The constructed device is composed of a toughen glass slab propped with 4 force sensors. Power transducers are connected to the measurement system based on a 24-bit ADC transducer which acquires slight body movements of a patient. The data is then transferred to the computer in real time and data analysis is conducted. The article explains the principle of operation as well as the algorithm of measurement uncertainty for the COP (Centre of Pressure surface (x, y.

  15. TECHNOLOGY SUPPORTED LEARNING PLATFORM: Moodle Integrated Academic Course

    Directory of Open Access Journals (Sweden)

    Saziye YAMAN

    2010-04-01

    Full Text Available It is substantially accepted that constructivism proposes knowledge as “not a fixed object”; constructed by an individual through her own experiences. As a learning theory, constructivism in education emphasizes collaborative learning, such as authentic challenging projects involving in students, teachers and experts in the learning community. Its goal is to create learning communities that are more closely related to the collaborative practice of the real world as strongly reflected in social constructivist idea. The technologies used in the filed of education will support learning through collaborative practices, using learners’ experiences for “meaning making”. The challenge now is to extend the educational networks so that it offers access to learning resources, online storage and tools for communication and management not just within the limitation of school and time. Through learning platforms, such as Moodle, teachers and administrators may bring hardware, software and supporting services together to enable more effective conditions among teachers and students. In this study, Moodle was used to support the 4th grade pre-service language teachers’ (student teachers one of the academic courses, named as “Field Experience”. The student teachers were expected to prepare graduation theses in the field of English language teaching. Moodle was integrated as a technological learning aid and used as online support throughout a semester course. So, we will discuss how Moodle was integrated as a learning platform, while discussing, the use of Moodle as a “course supporter” process, steps and the sample activities will be presented as well.

  16. Collaborative Development Planning Model of Supporting Product in Platform Innovation Ecosystem

    OpenAIRE

    Wei Zhang; Hamid Reza Karimi; Qingpu Zhang; Shaobo Wu

    2014-01-01

    In order to improve the market value of the product, the platform enterprise often participates in the development process of supporting product of emerging industry's platform innovation ecosystem. This paper puts forward a revenue sharing contract between the platform company and the supporting company by creating a collaborative development model of the supporting product in the ecosystem, and this paper studies the platform enterprise investment resource property's (complementary or subst...

  17. Miniaturized platform with on-chip strain sensors for compression testing of arrayed materials.

    Science.gov (United States)

    MacQueen, Luke; Chebotarev, Oleg; Simmons, Craig A; Sun, Yu

    2012-10-21

    We report a microfabricated mechanical testing platform with on-chip strain sensors for in situ mechanical characterization of arrayed materials. The device is based on deformable elastomeric membranes that are actuated by pressure that is delivered through an underlying channel network. The bulging membranes compress material samples that are confined between the membranes and a rigid top-plate. Carbon nanotube-based strain sensors that exhibit strain-dependent electrical resistivity were integrated within the membranes to provide continuous read-out of membrane deflection amplitude. We used this platform to study the cyclic compression of several different silicone samples and thereby measured their elastic moduli. The results obtained using our miniaturized platform were in excellent agreement with those obtained using a commercially available mechanical testing platform and clearly demonstrated the utility of our platform for the mechanical testing of small samples in parallel. The miniaturized platform can significantly increase mechanical testing efficiency, particularly when testing of iterative sample formulations is required.

  18. Employees' eldercare demands, strain, and perceived support

    NARCIS (Netherlands)

    Zacher, Hannes; Schulz, Heiko

    2015-01-01

    Purpose - In many countries, both the number of older people in need of care and the number of employed caregivers of elderly relatives will increase over the next decades. The purpose of this paper is to examine the extent to which perceived organizational, supervisor, and coworker support for elde

  19. Collaborative Development Planning Model of Supporting Product in Platform Innovation Ecosystem

    Directory of Open Access Journals (Sweden)

    Wei Zhang

    2014-01-01

    Full Text Available In order to improve the market value of the product, the platform enterprise often participates in the development process of supporting product of emerging industry’s platform innovation ecosystem. This paper puts forward a revenue sharing contract between the platform company and the supporting company by creating a collaborative development model of the supporting product in the ecosystem, and this paper studies the platform enterprise investment resource property's (complementary or substitution impact on the supporting enterprise R&D efforts and the revenue sharing factor and analyzes collaborative development mechanism of supporting product of emerging industry platform innovation ecosystem. The research indicates that when platform enterprise and supporting enterprise's resources are complementary, the supporting enterprise R&D effort level and revenue sharing coefficient increase as the platform company’s investment increases. When platform enterprise and supporting enterprise's resources are substitutive, the supporting enterprise’s R&D effort level and revenue sharing coefficient decrease as the platform company’s investment increases.

  20. Internet of things platforms in support of smart cities infrastructures

    CSIR Research Space (South Africa)

    Dlodlo, N

    2013-09-01

    Full Text Available the real and virtual worlds. This has been made possible through the development of IoT platforms. A city is referred to as ‘smart’ if it integrates smart objects into its products and services. The challenge is to integrate IoT platforms into the smart...

  1. Modal Strain Energy Based Structural Damage Localization for Offshore Platform using Simulated and Measured Data

    Institute of Scientific and Technical Information of China (English)

    WANG Shuqing; LIU Fushun; ZHANG Min

    2014-01-01

    Modal strain energy based methods for damage detection have received much attention. However, most of published articles use numerical methods and some studies conduct modal tests with simple 1D or 2D structures to verify the damage detection algorithms. Only a few studies utilize modal testing data from 3D frame structures. Few studies conduct performance comparisons between two different modal strain energy based methods. The objective of this paper is to investigate and compare the effectiveness of a traditional modal strain energy method (Stubbs index) and a recently developed modal strain energy decomposition (MSED) method for damage localization, for such a purpose both simulated and measured data from an offshore platform model being used. Particularly, the mode shapes used in the damage localization are identified and synthesized from only two measurements of one damage scenario because of the limited number of sensors. The two methods were first briefly reviewed. Next, using a 3D offshore platform model, the damage detection algorithms were implemented with different levels of damage severities for both single damage and multiple damage cases. Finally, a physical model of an offshore steel platform was constructed for modal testing and for validat-ing the applicability. Results indicate that the MSED method outperforms the Stubbs index method for structural damage detection.

  2. Organisational support for the EU platform level action to support innovative efforts for a new scholarly communication framework

    OpenAIRE

    Dekeyser, Raf

    2001-01-01

    Conclusions of the report of the panel discussion about the future of the scholarly communication "Organisational support for the EU platform level action to support innovative efforts for a new scholarly communication framework"

  3. Genomic analysis of thermophilic Bacillus coagulans strains: efficient producers for platform bio-chemicals.

    Science.gov (United States)

    Su, Fei; Xu, Ping

    2014-01-29

    Microbial strains with high substrate efficiency and excellent environmental tolerance are urgently needed for the production of platform bio-chemicals. Bacillus coagulans has these merits; however, little genetic information is available about this species. Here, we determined the genome sequences of five B. coagulans strains, and used a comparative genomic approach to reconstruct the central carbon metabolism of this species to explain their fermentation features. A novel xylose isomerase in the xylose utilization pathway was identified in these strains. Based on a genome-wide positive selection scan, the selection pressure on amino acid metabolism may have played a significant role in the thermal adaptation. We also researched the immune systems of B. coagulans strains, which provide them with acquired resistance to phages and mobile genetic elements. Our genomic analysis provides comprehensive insights into the genetic characteristics of B. coagulans and paves the way for improving and extending the uses of this species.

  4. PERGAMON: A serious gaming and digital coaching platform supporting patients and healthcare professionals

    NARCIS (Netherlands)

    Klaassen, Randy; Akker, op den Rieks; Di Bitonto, Pierpaolo; Burger, van der Gert-Jan; Bul, Kim; Kato, Pam; Varajão, J. E. Q.; Cruz-Cunha, M. M.; Martinho, R.; Rijo, R.; Bjørn-Andersen, N.; Turner, R.; Alves, D.

    2016-01-01

    This paper describes the design of a platform for serious gaming and digital coaching supporting healthcare and self-management of chronic patients. An instantiation of the platform outlined here supports self-management of adolescents with Type I diabetes that is integrated with their usual paediat

  5. IMPROVEMENT OF THE SUPPORTING STRUCTURE OF PLATFORM CAR FOR HIGHER EFFICIENCY OF CONTAINER TRANSPORTATIONS

    Directory of Open Access Journals (Sweden)

    A. O. Lovska

    2017-02-01

    Full Text Available Purpose. The article is aimed to improve supporting structures of the platform car to increase the efficiency of container transportations. Methodology. In order to achieve the objective, the strength investigations of the universal platform car of the model 13-401 were conducted, strength reserves of the supporting elements were defined, and more optimal profiles of basic longitudinal beams of the frame in terms of the minimum material capacity were proposed. Decision correctness was confirmed by the strength calculation of the platform car supporting structure at basic loading operational modes and fatigue taking into account the research database of 107 cycles. It has been proposed to equip a platform car with swing fitting stops for fastening containers on the frame, which allows transportation of 20ft and 40ft containers. In order to improve container transportation efficiency along international transport corridors running through Ukraine, a platform car of articulated type has been designed on the base of the improved platform car structure. The mathematical simulation of dynamic loads of the platform car with containers (two 1CC containers at operational loading modes has been carried out, the maximum accelerations influencing the support structure have been defined, and their multiple values have been considered in computer simulation of the strength of the platform car of articulated type. Findings. The support structure of the platform car of articulated type on the basis of the standard platform car has been developed. Refined values of dynamic loads influencing supporting structure the platform car of articulated type with containers at operational loading modes have been obtained; the maximum equivalent stresses in the platform car support structure have been defined. Originality and practical value. A mathematical model of displacements for a platform car of articulated type with containers at operational loading modes of

  6. An Interoperable Federated Naming Service Supporting a Pan-European Service Platform

    NARCIS (Netherlands)

    van Halteren, Aart; Tangey, P.; Walsh, V.

    1998-01-01

    This paper describes the implementation of a Federated Naming Service required for a widely distributed multi-ORB heterogeneous platform. This platform is being built to demonstrate and test the applicability of CORBA technology and TINA principles to support Telecommunication Public Network

  7. An Interoperable Federated Naming Service - Supporting a Pan-European Service Platform

    NARCIS (Netherlands)

    Halteren, van A.T.; Tangey, P.; Walsh, V.

    1998-01-01

    This paper describes the implementation of a Federated Naming Service required for a widely distributed multi-ORB heterogeneous platform. This platform is being built to demonstrate and test the applicability of CORBA technology and TINA principles to support Telecommunication Public Network Operato

  8. WLAN Positioning Methods and Supporting Learning Technologies for Mobile Platforms

    Science.gov (United States)

    Melkonyan, Arsen

    2013-01-01

    Location technologies constitute an essential component of systems design for autonomous operations and control. The Global Positioning System (GPS) works well in outdoor areas, but the satellite signals are not strong enough to penetrate inside most indoor environments. As a result, a new strain of indoor positioning technologies that make use of…

  9. Design and Validation of Equiaxial Mechanical Strain Platform, EQUicycler, for 3D Tissue Engineered Constructs.

    Science.gov (United States)

    Elsaadany, Mostafa; Harris, Matthew; Yildirim-Ayan, Eda

    2017-01-01

    It is crucial to replicate the micromechanical milieu of native tissues to achieve efficacious tissue engineering and regenerative therapy. In this study, we introduced an innovative loading platform, EQUicycler, that utilizes a simple, yet effective, and well-controlled mechanism to apply physiologically relevant homogenous mechanical equiaxial strain on three-dimensional cell-embedded tissue scaffolds. The design of EQUicycler ensured elimination of gripping effects through the use of biologically compatible silicone posts for direct transfer of the mechanical load to the scaffolds. Finite Element Modeling (FEM) was created to understand and to quantify how much applied global strain was transferred from the loading mechanism to the tissue constructs. In vitro studies were conducted on various cell lines associated with tissues exposed to equiaxial mechanical loading in their native environment. In vitro results demonstrated that EQUicycler was effective in maintaining and promoting the viability of different musculoskeletal cell lines and upregulating early differentiation of osteoprogenitor cells. By utilizing EQUicycler, collagen fibers of the constructs were actively remodeled. Residing cells within the collagen construct elongated and aligned with strain direction upon mechanical loading. EQUicycler can provide an efficient and cost-effective tool to conduct mechanistic studies for tissue engineered constructs designed for tissue systems under mechanical loading in vivo.

  10. MIDAS intelligent platform for medical services, support for decision optimization in virtual medical communities.

    Science.gov (United States)

    Arotăriţei, D; Toma, C M; Turnea, M; Toma, Vasilica

    2008-01-01

    The paper describes the implementation of a open multifunctional platform--MIDAS--for heterogeneous medical data management--support for optimization of clinical decision in virtual medical communities. The objectives of this intelligent environment are: diagnostic easier by access to heterogeneous medical data, a virtual support for medical personal in order to reduce medical errors, fast access to resources for education and improvement of medical education for physicians and students. The structure of the platform is based on a core module and a number of dedicated modules that give an important advantage as re-configurable platform depending on necessities. The core module tries to be as general is possible in order to be used in the future as core model in a platform focused on dentistry cases.

  11. Risk Analysis of Return Support Material on Gas Compressor Platform Project

    Science.gov (United States)

    Silvianita; Aulia, B. U.; Khakim, M. L. N.; Rosyid, Daniel M.

    2017-07-01

    On a fixed platforms project are not only carried out by a contractor, but two or more contractors. Cooperation in the construction of fixed platforms is often not according to plan, it is caused by several factors. It takes a good synergy between the contractor to avoid miss communication may cause problems on the project. For the example is about support material (sea fastening, skid shoe and shipping support) used in the process of sending a jacket structure to operation place often does not return to the contractor. It needs a systematic method to overcome the problem of support material. This paper analyses the causes and effects of GAS Compressor Platform that support material is not return, using Fault Tree Analysis (FTA) and Event Tree Analysis (ETA). From fault tree analysis, the probability of top event is 0.7783. From event tree analysis diagram, the contractors lose Rp.350.000.000, - to Rp.10.000.000.000, -.

  12. Technology licensing by advertising supported media platforms: An application to internet search engines

    OpenAIRE

    Sapi, Geza; Suleymanova, Irina

    2011-01-01

    We develop a duopoly model with advertising supported platforms and analyze incentives of a superior firm to license its advanced technologies to an inferior rival. We highlight the role of two technologies characteristic for media platforms: The technology to produce content and to place advertisements. Licensing incentives are driven solely by indirect network effects arising fromthe aversion of users to advertising. We establish a relationship between licensing incentives and the nature of...

  13. Prototype of a Web-based Participative Decision Support Platform in Natural Hazards and Risk Management

    Directory of Open Access Journals (Sweden)

    Zar Chi Aye

    2015-07-01

    Full Text Available This paper presents the current state and development of a prototype web-GIS (Geographic Information System decision support platform intended for application in natural hazards and risk management, mainly for floods and landslides. This web platform uses open-source geospatial software and technologies, particularly the Boundless (formerly OpenGeo framework and its client side software development kit (SDK. The main purpose of the platform is to assist the experts and stakeholders in the decision-making process for evaluation and selection of different risk management strategies through an interactive participation approach, integrating web-GIS interface with decision support tool based on a compromise programming approach. The access rights and functionality of the platform are varied depending on the roles and responsibilities of stakeholders in managing the risk. The application of the prototype platform is demonstrated based on an example case study site: Malborghetto Valbruna municipality of North-Eastern Italy where flash floods and landslides are frequent with major events having occurred in 2003. The preliminary feedback collected from the stakeholders in the region is discussed to understand the perspectives of stakeholders on the proposed prototype platform.

  14. A Caregiver Support Platform within the Scope of an Ambient Assisted Living Ecosystem

    Directory of Open Access Journals (Sweden)

    Angelo Costa

    2014-03-01

    Full Text Available The Ambient Assisted Living (AAL area is in constant evolution, providing new technologies to users and enhancing the level of security and comfort that is ensured by house platforms. The Ambient Assisted Living for All (AAL4ALL project aims to develop a new AAL concept, supported on a unified ecosystem and certification process that enables a heterogeneous environment. The concepts of Intelligent Environments, Ambient Intelligence, and the foundations of the Ambient Assisted Living are all presented in the framework of this project. In this work, we consider a specific platform developed in the scope of AAL4ALL, called UserAccess. The architecture of the platform and its role within the overall AAL4ALL concept, the implementation of the platform, and the available interfaces are presented. In addition, its feasibility is validated through a series of tests.

  15. The OCarePlatform: A context-aware system to support independent living.

    Science.gov (United States)

    De Backere, F; Bonte, P; Verstichel, S; Ongenae, F; De Turck, F

    2017-03-01

    Currently, healthcare services, such as institutional care facilities, are burdened with an increasing number of elderly people and individuals with chronic illnesses and a decreasing number of competent caregivers. To relieve the burden on healthcare services, independent living at home could be facilitated, by offering individuals and their (in)formal caregivers support in their daily care and needs. With the rise of pervasive healthcare, new information technology solutions can assist elderly people ("residents") and their caregivers to allow residents to live independently for as long as possible. To this end, the OCarePlatform system was designed. This semantic, data-driven and cloud-based back-end system facilitates independent living by offering information and knowledge-based services to the resident and his/her (in)formal caregivers. Data and context information are gathered to realize context-aware and personalized services and to support residents in meeting their daily needs. This body of data, originating from heterogeneous data and information sources, is sent to personalized services, where is fused, thus creating an overview of the resident's current situation. The architecture of the OCarePlatform is proposed, which is based on a service-oriented approach, together with its different components and their interactions. The implementation details are presented, together with a running example. A scalability and performance study of the OCarePlatform was performed. The results indicate that the OCarePlatform is able to support a realistic working environment and respond to a trigger in less than 5 seconds. The system is highly dependent on the allocated memory. The data-driven character of the OCarePlatform facilitates easy plug-in of new functionality, enabling the design of personalized, context-aware services. The OCarePlatform leads to better support for elderly people and individuals with chronic illnesses, who live independently. Copyright

  16. Web-service architecture for tools supporting life-long e-Learning platforms

    NARCIS (Netherlands)

    Dimov, Alexander; Stefanov, Krassen

    2009-01-01

    Dimov, A., & Stefanov, K. (2008). Web-service architecture for tools supporting life-long e-Learning platforms. In R. Koper, K. Stefanov & D. Dicheva (Eds.), Proceedings of the 5th International TENCompetence Open Workshop "Stimulating Personal Development and Knowledge Sharing" (pp. 67-71).

  17. A Contextualised Multi-Platform Framework to Support Blended Learning Scenarios in Learning Networks

    NARCIS (Netherlands)

    De Jong, Tim; Fuertes, Alba; Schmeits, Tally; Specht, Marcus; Koper, Rob

    2008-01-01

    De Jong, T., Fuertes, A., Schmeits, T., Specht, M., & Koper, R. (2009). A Contextualised Multi-Platform Framework to Support Blended Learning Scenarios in Learning Networks. In D. Goh (Ed.), Multiplatform E-Learning Systems and Technologies: Mobile Devices for Ubiquitous ICT-Based Education (pp. 1-1

  18. Web-service architecture for tools supporting life-long e-Learning platforms

    NARCIS (Netherlands)

    Dimov, Alexander; Stefanov, Krassen

    2009-01-01

    Dimov, A., & Stefanov, K. (2008). Web-service architecture for tools supporting life-long e-Learning platforms. In R. Koper, K. Stefanov & D. Dicheva (Eds.), Proceedings of the 5th International TENCompetence Open Workshop "Stimulating Personal Development and Knowledge Sharing" (pp. 67-71). October

  19. Agent-oriented context-aware platforms supporting communities of practice in health care

    NARCIS (Netherlands)

    Bonino da Silva Santos, L.O.; Guizzardi-Silva Souza, R.; Sinderen, van M.J.

    2005-01-01

    This paper presents and discusses the use of an agent-oriented context-aware platform to support communities of practice (CoPs) in the health care domain. Our work is based on a scenario where CoPs are applied in a hospital to enhance the knowledge sharing among the staff members who share interests

  20. A Contextualised Multi-Platform Framework to Support Blended Learning Scenarios in Learning Networks

    NARCIS (Netherlands)

    De Jong, Tim; Fuertes, Alba; Schmeits, Tally; Specht, Marcus; Koper, Rob

    2008-01-01

    De Jong, T., Fuertes, A., Schmeits, T., Specht, M., & Koper, R. (2009). A Contextualised Multi-Platform Framework to Support Blended Learning Scenarios in Learning Networks. In D. Goh (Ed.), Multiplatform E-Learning Systems and Technologies: Mobile Devices for Ubiquitous ICT-Based Education (pp.

  1. Supporting Real-Time Computer Vision Workloads using OpenVX on Multicore+GPU Platforms

    Science.gov (United States)

    2015-05-01

    workloads specified using OpenVX to be supported in a predictable way. I. INTRODUCTION In the automotive industry today, vision-based sensing through cameras...Supporting Real-Time Computer Vision Workloads using OpenVX on Multicore+GPU Platforms Glenn A. Elliott, Kecheng Yang, and James H. Anderson...Department of Computer Science, University of North Carolina at Chapel Hill Abstract—In the automotive industry, there is currently great interest in

  2. Building a knowledge translation platform in Malawi to support evidence-informed health policy.

    Science.gov (United States)

    Berman, Joshua; Mitambo, Collins; Matanje-Mwagomba, Beatrice; Khan, Shiraz; Kachimanga, Chiyembekezo; Wroe, Emily; Mwape, Lonia; van Oosterhout, Joep J; Chindebvu, Getrude; van Schoor, Vanessa; Puchalski Ritchie, Lisa M; Panisset, Ulysses; Kathyola, Damson

    2015-12-08

    With the support of the World Health Organization's Evidence-Informed Policy Network, knowledge translation platforms have been developed throughout Africa, the Americas, Eastern Europe, and Asia to further evidence-informed national health policy. In this commentary, we discuss the approaches, activities and early lessons learned from the development of a Knowledge Translation Platform in Malawi (KTPMalawi). Through ongoing leadership, as well as financial and administrative support, the Malawi Ministry of Health has strongly signalled its intention to utilize a knowledge translation platform methodology to support evidence-informed national health policy. A unique partnership between Dignitas International, a medical and research non-governmental organization, and the Malawi Ministry of Health, has established KTPMalawi to engage national-level policymakers, researchers and implementers in a coordinated approach to the generation and utilization of health-sector research. Utilizing a methodology developed and tested by knowledge translation platforms across Africa, a stakeholder mapping exercise and initial capacity building workshops were undertaken and a multidisciplinary Steering Committee was formed. This Steering Committee prioritized the development of two initial Communities of Practice to (1) improve data utilization in the pharmaceutical supply chain and (2) improve the screening and treatment of hypertension within HIV-infected populations. Each Community of Practice's mandate is to gather and synthesize the best available global and local evidence and produce evidence briefs for policy that have been used as the primary input into structured deliberative dialogues. While a lack of sustained initial funding slowed its early development, KTPMalawi has greatly benefited from extensive technical support and mentorship by an existing network of global knowledge translation platforms. With the continued support of the Malawi Ministry of Health and the

  3. In-fiber rectangular air fabry-perot strain sensor based on high-precision fiber cutting platform

    Science.gov (United States)

    Zhao, Yong; Chen, Mao-qing; Lv, Ri-qing; Xia, Feng

    2017-02-01

    An in-fiber rectangular air Fabry-Perot (FP) strain sensor based on a high-precision fiber cutting platform (HFCP) is proposed. The HFCP consisting of a CCD notation system, a micro-displacement platform, and an optical fiber cleaver can be used to precisely control the length of FP cavity. The microcavity of FP (even only tens of microns) with smooth reflective surface can be realized easily by using this system. The FP structures with different cavity lengths have been fabricated in this paper. Simulation and experimental results prove that the shorter length the cavity has, the higher strain sensitivity and the larger free spectral range (FSR) the sensor obtains. The strain sensitivity and FSR of in-fiber rectangular air FP sensor with a cavity length of 35 μm can be up to 2.23 pm/με and 28.5 nm respectively. Moreover, the proposed FP strain sensor has a negligible temperature sensitivity in the range of 25-75 °C. It is anticipated that such easy making, compact and low-cost fiber-optic strain sensors could find important applications in practice.

  4. SemanticSCo: A platform to support the semantic composition of services for gene expression analysis.

    Science.gov (United States)

    Guardia, Gabriela D A; Ferreira Pires, Luís; da Silva, Eduardo G; de Farias, Cléver R G

    2017-02-01

    Gene expression studies often require the combined use of a number of analysis tools. However, manual integration of analysis tools can be cumbersome and error prone. To support a higher level of automation in the integration process, efforts have been made in the biomedical domain towards the development of semantic web services and supporting composition environments. Yet, most environments consider only the execution of simple service behaviours and requires users to focus on technical details of the composition process. We propose a novel approach to the semantic composition of gene expression analysis services that addresses the shortcomings of the existing solutions. Our approach includes an architecture designed to support the service composition process for gene expression analysis, and a flexible strategy for the (semi) automatic composition of semantic web services. Finally, we implement a supporting platform called SemanticSCo to realize the proposed composition approach and demonstrate its functionality by successfully reproducing a microarray study documented in the literature. The SemanticSCo platform provides support for the composition of RESTful web services semantically annotated using SAWSDL. Our platform also supports the definition of constraints/conditions regarding the order in which service operations should be invoked, thus enabling the definition of complex service behaviours. Our proposed solution for semantic web service composition takes into account the requirements of different stakeholders and addresses all phases of the service composition process. It also provides support for the definition of analysis workflows at a high-level of abstraction, thus enabling users to focus on biological research issues rather than on the technical details of the composition process. The SemanticSCo source code is available at https://github.com/usplssb/SemanticSCo. Copyright © 2017 Elsevier Inc. All rights reserved.

  5. Supporting Medical Research on Chronic Diseases using Integrated Health Monitoring Platform

    OpenAIRE

    Krukowski, Artur; Vogiatzaki, Emmanouela; Charalambides, Marios; Chouchoulis, Michalis

    2014-01-01

    This paper describes combined experiences in developing e-Health platforms and services with respect of supporting medical research into the causes and relationships among physiological parameters and health problems concerning different chronic diseases, from cardiovascular to stroke, epilepsy, and others. The Personal Health Records (PHR) is presented as new technological approaches aimed at standardizing electronic management of medical information between the patient and its physicians, a...

  6. An Open Platform for Seamless Sensor Support in Healthcare for the Internet of Things

    Directory of Open Access Journals (Sweden)

    Jorge Miranda

    2016-12-01

    Full Text Available Population aging and increasing pressure on health systems are two issues that demand solutions. Involving and empowering citizens as active managers of their health represents a desirable shift from the current culture mainly focused on treatment of disease, to one also focused on continuous health management and well-being. Current developments in technological areas such as the Internet of Things (IoT, lead to new technological solutions that can aid this shift in the healthcare sector. This study presents the design, development, implementation and evaluation of a platform called Common Recognition and Identification Platform (CRIP, a part of the CareStore project, which aims at supporting caregivers and citizens to manage health routines in a seamless way. Specifically, the CRIP offers sensor-based support for seamless identification of users and health devices. A set of initial requirements was defined with a focus on usability limitations and current sensor technologies. The CRIP was designed and implemented using several technologies that enable seamless integration and interaction of sensors and people, namely Near Field Communication and fingerprint biometrics for identification and authentication, Bluetooth for communication with health devices and web services for wider integration with other platforms. Two CRIP prototypes were implemented and evaluated in laboratory during a period of eight months. The evaluations consisted of identifying users and devices, as well as seamlessly configure and acquire vital data from the last. Also, the entire Carestore platform was deployed in a nursing home where its usability was evaluated with caregivers. The evaluations helped assess that seamless identification of users and seamless configuration and communication with health devices is feasible and can help enable the IoT on healthcare applications. Therefore, the CRIP and similar platforms could be transformed into a valuable enabling

  7. An Open Platform for Seamless Sensor Support in Healthcare for the Internet of Things

    Science.gov (United States)

    Miranda, Jorge; Cabral, Jorge; Wagner, Stefan Rahr; Fischer Pedersen, Christian; Ravelo, Blaise; Memon, Mukhtiar; Mathiesen, Morten

    2016-01-01

    Population aging and increasing pressure on health systems are two issues that demand solutions. Involving and empowering citizens as active managers of their health represents a desirable shift from the current culture mainly focused on treatment of disease, to one also focused on continuous health management and well-being. Current developments in technological areas such as the Internet of Things (IoT), lead to new technological solutions that can aid this shift in the healthcare sector. This study presents the design, development, implementation and evaluation of a platform called Common Recognition and Identification Platform (CRIP), a part of the CareStore project, which aims at supporting caregivers and citizens to manage health routines in a seamless way. Specifically, the CRIP offers sensor-based support for seamless identification of users and health devices. A set of initial requirements was defined with a focus on usability limitations and current sensor technologies. The CRIP was designed and implemented using several technologies that enable seamless integration and interaction of sensors and people, namely Near Field Communication and fingerprint biometrics for identification and authentication, Bluetooth for communication with health devices and web services for wider integration with other platforms. Two CRIP prototypes were implemented and evaluated in laboratory during a period of eight months. The evaluations consisted of identifying users and devices, as well as seamlessly configure and acquire vital data from the last. Also, the entire Carestore platform was deployed in a nursing home where its usability was evaluated with caregivers. The evaluations helped assess that seamless identification of users and seamless configuration and communication with health devices is feasible and can help enable the IoT on healthcare applications. Therefore, the CRIP and similar platforms could be transformed into a valuable enabling technology for secure and

  8. An Open Platform for Seamless Sensor Support in Healthcare for the Internet of Things.

    Science.gov (United States)

    Miranda, Jorge; Cabral, Jorge; Wagner, Stefan Rahr; Fischer Pedersen, Christian; Ravelo, Blaise; Memon, Mukhtiar; Mathiesen, Morten

    2016-12-08

    Population aging and increasing pressure on health systems are two issues that demand solutions. Involving and empowering citizens as active managers of their health represents a desirable shift from the current culture mainly focused on treatment of disease, to one also focused on continuous health management and well-being. Current developments in technological areas such as the Internet of Things (IoT), lead to new technological solutions that can aid this shift in the healthcare sector. This study presents the design, development, implementation and evaluation of a platform called Common Recognition and Identification Platform (CRIP), a part of the CareStore project, which aims at supporting caregivers and citizens to manage health routines in a seamless way. Specifically, the CRIP offers sensor-based support for seamless identification of users and health devices. A set of initial requirements was defined with a focus on usability limitations and current sensor technologies. The CRIP was designed and implemented using several technologies that enable seamless integration and interaction of sensors and people, namely Near Field Communication and fingerprint biometrics for identification and authentication, Bluetooth for communication with health devices and web services for wider integration with other platforms. Two CRIP prototypes were implemented and evaluated in laboratory during a period of eight months. The evaluations consisted of identifying users and devices, as well as seamlessly configure and acquire vital data from the last. Also, the entire Carestore platform was deployed in a nursing home where its usability was evaluated with caregivers. The evaluations helped assess that seamless identification of users and seamless configuration and communication with health devices is feasible and can help enable the IoT on healthcare applications. Therefore, the CRIP and similar platforms could be transformed into a valuable enabling technology for secure and

  9. An E-government Interoperability Platform Supporting Personal Data Protection Regulations

    Directory of Open Access Journals (Sweden)

    Laura González

    2016-08-01

    Full Text Available Public agencies are increasingly required to collaborate with each other in order to provide high-quality e-government services. This collaboration is usually based on the service-oriented approach and supported by interoperability platforms. Such platforms are specialized middleware-based infrastructures enabling the provision, discovery and invocation of interoperable software services. In turn, given that personal data handled by governments are often very sensitive, most governments have developed some sort of legislation focusing on data protection. This paper proposes solutions for monitoring and enforcing data protection laws within an E-government Interoperability Platform. In particular, the proposal addresses requirements posed by the Uruguayan Data Protection Law and the Uruguayan E-government Platform, although it can also be applied in similar scenarios. The solutions are based on well-known integration mechanisms (e.g. Enterprise Service Bus as well as recognized security standards (e.g. eXtensible Access Control Markup Language and were completely prototyped leveraging the SwitchYard ESB product.

  10. Supporting Building Portfolio Investment and Policy Decision Making through an Integrated Building Utility Data Platform

    Energy Technology Data Exchange (ETDEWEB)

    Aziz, Azizan [Carnegie Mellon Univ., Pittsburgh, PA (United States); Lasternas, Bertrand [Carnegie Mellon Univ., Pittsburgh, PA (United States); Alschuler, Elena [US DOE; View Inc; Loftness, Vivian [Carnegie Mellon Univ., Pittsburgh, PA (United States); Wang, Haopeng [Carnegie Mellon Univ., Pittsburgh, PA (United States); Mo, Yunjeong [Carnegie Mellon Univ., Pittsburgh, PA (United States); Wang, Ting [Carnegie Mellon Univ., Pittsburgh, PA (United States); Zhang, Chenlu [Carnegie Mellon Univ., Pittsburgh, PA (United States); Sharma, Shilpi [Carnegie Mellon; Stevens, Ivana [Carnegie Mellon Univ., Pittsburgh, PA (United States)

    2016-03-18

    The American Recovery and Reinvestment Act stimulus funding of 2009 for smart grid projects resulted in the tripling of smart meters deployment. In 2012, the Green Button initiative provided utility customers with access to their real-time1 energy usage. The availability of finely granular data provides an enormous potential for energy data analytics and energy benchmarking. The sheer volume of time-series utility data from a large number of buildings also poses challenges in data collection, quality control, and database management for rigorous and meaningful analyses. In this paper, we will describe a building portfolio-level data analytics tool for operational optimization, business investment and policy assessment using 15-minute to monthly intervals utility data. The analytics tool is developed on top of the U.S. Department of Energy’s Standard Energy Efficiency Data (SEED) platform, an open source software application that manages energy performance data of large groups of buildings. To support the significantly large volume of granular interval data, we integrated a parallel time-series database to the existing relational database. The time-series database improves on the current utility data input, focusing on real-time data collection, storage, analytics and data quality control. The fully integrated data platform supports APIs for utility apps development by third party software developers. These apps will provide actionable intelligence for building owners and facilities managers. Unlike a commercial system, this platform is an open source platform funded by the U.S. Government, accessible to the public, researchers and other developers, to support initiatives in reducing building energy consumption.

  11. Dynamic Analysis of Tension Leg Platform for Offshore Wind Turbine Support as Fluid-Structure Interaction

    Institute of Scientific and Technical Information of China (English)

    HUANG Hu; ZHANG She-rong

    2011-01-01

    Tension leg platform(TLP)for offshore wind turbine support is a new type structure in wind energy utilization.The strong-interaction method is used in analyzing the coupled model,and the dynamic characteristics of the TLP for offshore wind turbine support are recognized.As shown by the calculated results:for the lower modes,the shapes are water's vibration,and the vibration of water induces the structure's swing;the mode shapes of the structure are complex,and can largely change among different members;the mode shapes of the platform are related to the tower's.The frequencies of the structure do not change much after adjusting the length of the tension cables and the depth of the platform;the TLP has good adaptability for the water depths and the environment loads.The change of the size and parameters of TLP can improve the dynamic characteristics,which can reduce the vibration of the TLP caused by the loads.Through the vibration analysis,the natural vibration frequencies of TLP can be distinguished from the frequencies of condition loads,and thus the resonance vibration can be avoided,therefore the offshore wind turbine can work normally in the complex conditions.

  12. A CLOUD-BASED PLATFORM SUPPORTING GEOSPATIAL COLLABORATION FOR GIS EDUCATION

    Directory of Open Access Journals (Sweden)

    X. Cheng

    2015-05-01

    Full Text Available GIS-related education needs support of geo-data and geospatial software. Although there are large amount of geographic information resources distributed on the web, the discovery, process and integration of these resources are still unsolved. Researchers and teachers always searched geo-data by common search engines but results were not satisfied. They also spent much money and energy on purchase and maintenance of various kinds of geospatial software. Aimed at these problems, a cloud-based geospatial collaboration platform called GeoSquare was designed and implemented. The platform serves as a geoportal encouraging geospatial data, information, and knowledge sharing through highly interactive and expressive graphic interfaces. Researchers and teachers can solve their problems effectively in this one-stop solution. Functions, specific design and implementation details are presented in this paper. Site of GeoSquare is: http://geosquare.tianditu.com/

  13. Bench-Scale Filtration Testing in Support of the Pretreatment Engineering Platform (PEP)

    Energy Technology Data Exchange (ETDEWEB)

    Billing, Justin M.; Daniel, Richard C.; Kurath, Dean E.; Peterson, Reid A.

    2009-09-28

    Pacific Northwest National Laboratory (PNNL) has been tasked by Bechtel National Inc. (BNI) on the River Protection Project-Hanford Tank Waste Treatment and Immobilization Plant (RPP-WTP) project to perform research and development activities to resolve technical issues identified for the Pretreatment Facility (PTF). The Pretreatment Engineering Platform (PEP) was designed, constructed and operated as part of a plan to respond to issue M12, “Undemonstrated Leaching Processes.” The PEP is a 1/4.5-scale test platform designed to simulate the WTP pretreatment caustic leaching, oxidative leaching, ultrafiltration solids concentration, and slurry washing processes. The PEP testing program specifies that bench-scale testing is to be performed in support of specific operations, including filtration, caustic leaching, and oxidative leaching.

  14. Development and Validation of a Portable Platform for Deploying Decision-Support Algorithms in Prehospital Settings

    Science.gov (United States)

    Reisner, A. T.; Khitrov, M. Y.; Chen, L.; Blood, A.; Wilkins, K.; Doyle, W.; Wilcox, S.; Denison, T.; Reifman, J.

    2013-01-01

    Summary Background Advanced decision-support capabilities for prehospital trauma care may prove effective at improving patient care. Such functionality would be possible if an analysis platform were connected to a transport vital-signs monitor. In practice, there are technical challenges to implementing such a system. Not only must each individual component be reliable, but, in addition, the connectivity between components must be reliable. Objective We describe the development, validation, and deployment of the Automated Processing of Physiologic Registry for Assessment of Injury Severity (APPRAISE) platform, intended to serve as a test bed to help evaluate the performance of decision-support algorithms in a prehospital environment. Methods We describe the hardware selected and the software implemented, and the procedures used for laboratory and field testing. Results The APPRAISE platform met performance goals in both laboratory testing (using a vital-sign data simulator) and initial field testing. After its field testing, the platform has been in use on Boston MedFlight air ambulances since February of 2010. Conclusion These experiences may prove informative to other technology developers and to healthcare stakeholders seeking to invest in connected electronic systems for prehospital as well as in-hospital use. Our experiences illustrate two sets of important questions: are the individual components reliable (e.g., physical integrity, power, core functionality, and end-user interaction) and is the connectivity between components reliable (e.g., communication protocols and the metadata necessary for data interpretation)? While all potential operational issues cannot be fully anticipated and eliminated during development, thoughtful design and phased testing steps can reduce, if not eliminate, technical surprises. PMID:24155791

  15. Construction of a Corynebacterium glutamicum platform strain for the production of stilbenes and (2S)-flavanones.

    Science.gov (United States)

    Kallscheuer, Nicolai; Vogt, Michael; Stenzel, Anton; Gätgens, Jochem; Bott, Michael; Marienhagen, Jan

    2016-11-01

    Corynebacterium glutamicum is an important organism in industrial biotechnology for the microbial production of bulk chemicals, in particular amino acids. However, until now activity of a complex catabolic network for the degradation of aromatic compounds averted application of C. glutamicum as production host for aromatic compounds of pharmaceutical or biotechnological interest. In the course of the construction of a suitable C. glutamicum platform strain for plant polyphenol production, four gene clusters comprising 21 genes involved in the catabolism of aromatic compounds were deleted. Expression of plant-derived and codon-optimized genes coding for a chalcone synthase (CHS) and a chalcone isomerase (CHI) in this strain background enabled formation of 35mg/L naringenin and 37mg/L eriodictyol from the supplemented phenylpropanoids p-coumaric acid and caffeic acid, respectively. Furthermore, expression of genes coding for a 4-coumarate: CoA-ligase (4CL) and a stilbene synthase (STS) led to the production of the stilbenes pinosylvin, resveratrol and piceatannol starting from supplemented phenylpropanoids cinnamic acid, p-coumaric acid and caffeic acid, respectively. Stilbene concentrations of up to 158mg/L could be achieved. Additional engineering of the amino acid metabolism for an optimal connection to the synthetic plant polyphenol pathways enabled resveratrol production directly from glucose. The construction of these C. glutamicum platform strains for the synthesis of plant polyphenols opens the door towards the microbial production of high-value aromatic compounds from cheap carbon sources with this microorganism.

  16. Support for Taverna workflows in the VPH-Share cloud platform.

    Science.gov (United States)

    Kasztelnik, Marek; Coto, Ernesto; Bubak, Marian; Malawski, Maciej; Nowakowski, Piotr; Arenas, Juan; Saglimbeni, Alfredo; Testi, Debora; Frangi, Alejandro F

    2017-07-01

    To address the increasing need for collaborative endeavours within the Virtual Physiological Human (VPH) community, the VPH-Share collaborative cloud platform allows researchers to expose and share sequences of complex biomedical processing tasks in the form of computational workflows. The Taverna Workflow System is a very popular tool for orchestrating complex biomedical & bioinformatics processing tasks in the VPH community. This paper describes the VPH-Share components that support the building and execution of Taverna workflows, and explains how they interact with other VPH-Share components to improve the capabilities of the VPH-Share platform. Taverna workflow support is delivered by the Atmosphere cloud management platform and the VPH-Share Taverna plugin. These components are explained in detail, along with the two main procedures that were developed to enable this seamless integration: workflow composition and execution. 1) Seamless integration of VPH-Share with other components and systems. 2) Extended range of different tools for workflows. 3) Successful integration of scientific workflows from other VPH projects. 4) Execution speed improvement for medical applications. The presented workflow integration provides VPH-Share users with a wide range of different possibilities to compose and execute workflows, such as desktop or online composition, online batch execution, multithreading, remote execution, etc. The specific advantages of each supported tool are presented, as are the roles of Atmosphere and the VPH-Share plugin within the VPH-Share project. The combination of the VPH-Share plugin and Atmosphere engenders the VPH-Share infrastructure with far more flexible, powerful and usable capabilities for the VPH-Share community. As both components can continue to evolve and improve independently, we acknowledge that further improvements are still to be developed and will be described. Copyright © 2017 Elsevier B.V. All rights reserved.

  17. IMGD: an integrated platform supporting comparative genomics and phylogenetics of insect mitochondrial genomes

    Directory of Open Access Journals (Sweden)

    Jung Kyongyong

    2009-04-01

    Full Text Available Abstract Background Sequences and organization of the mitochondrial genome have been used as markers to investigate evolutionary history and relationships in many taxonomic groups. The rapidly increasing mitochondrial genome sequences from diverse insects provide ample opportunities to explore various global evolutionary questions in the superclass Hexapoda. To adequately support such questions, it is imperative to establish an informatics platform that facilitates the retrieval and utilization of available mitochondrial genome sequence data. Results The Insect Mitochondrial Genome Database (IMGD is a new integrated platform that archives the mitochondrial genome sequences from 25,747 hexapod species, including 112 completely sequenced and 20 nearly completed genomes and 113,985 partially sequenced mitochondrial genomes. The Species-driven User Interface (SUI of IMGD supports data retrieval and diverse analyses at multi-taxon levels. The Phyloviewer implemented in IMGD provides three methods for drawing phylogenetic trees and displays the resulting trees on the web. The SNP database incorporated to IMGD presents the distribution of SNPs and INDELs in the mitochondrial genomes of multiple isolates within eight species. A newly developed comparative SNU Genome Browser supports the graphical presentation and interactive interface for the identified SNPs/INDELs. Conclusion The IMGD provides a solid foundation for the comparative mitochondrial genomics and phylogenetics of insects. All data and functions described here are available at the web site http://www.imgd.org/.

  18. Dynamic composition of medical support services in the ICU: Platform and algorithm design details.

    Science.gov (United States)

    Hristoskova, Anna; Moeyersoon, Dieter; Van Hoecke, Sofie; Verstichel, Stijn; Decruyenaere, Johan; De Turck, Filip

    2010-12-01

    The Intensive Care Unit (ICU) is an extremely data-intensive environment where each patient needs to be monitored 24/7. Bedside monitors continuously register vital patient values (such as serum creatinine, systolic blood pressure) which are recorded frequently in the hospital database (e.g. every 2 min in the ICU of the Ghent University Hospital), laboratories generate hundreds of results of blood and urine samples, and nurses measure blood pressure and temperature up to 4 times an hour. The processing of such large amount of data requires an automated system to support the physicians' daily work. The Intensive Care Service Platform (ICSP) offers the needed support through the development of medical support services for processing and monitoring patients' data. With an increased deployment of these medical support services, reusing existing services as building blocks to create new services offers flexibility to the developer and accelerates the design process. This paper presents a new addition to the ICSP, the Dynamic Composer for Web services. Based on a semantic description of the medical support services, this Composer enables a service to be executed by creating a composition of medical services that provide the needed calculations. The composition is achieved using various algorithms satisfying certain quality of service (QoS) constraints and requirements. In addition to the automatic composition the paper also proposes a recovery mechanism in case of unavailable services. When executing the composition of medical services, unavailable services are dynamically replaced by equivalent services or a new composition achieving the same result. The presented platform and QoS algorithms are put through extensive performance and scalability tests for typical ICU scenarios, in which basic medical services are composed to a complex patient monitoring service.

  19. The Construction of a Web-Based Learning Platform from the Perspective of Computer Support for Collaborative Design

    Directory of Open Access Journals (Sweden)

    Cheng Mei

    2012-04-01

    Full Text Available The purpose of this study is to construct a web-based learning platform of Computer Support for Collaborative Design (CSCD based on theories related to a constructivist learning environment model, mind mapping and computer-supported collaborative learning. The platform conforms to the needs of design students and provides effective tools for interaction and collaborative learning by integrating the tools of mind mapping into a learning environment that utilizes CSCD, a computer-assisted support system that can support and enhance group collaboration. The establishment of the CSCD learning platform represents a significant advance from the fixed functions and existing models of current online learning platforms and is the only learning platform in the world that focuses on learners in design departments. The platform is outstanding for its excellence, user-friendly functions, and innovative technology. In terms of funding, technical ability, human resources, organizational strategies, and risk analysis and evaluations, the learning platform is also worthy of expansion and implementation.

  20. An integrated bioanalytical platform for supporting high-throughput serum protein binding screening.

    Science.gov (United States)

    Zhang, Jun; Shou, Wilson Z; Vath, Marianne; Kieltyka, Kasia; Maloney, Jennifer; Elvebak, Larry; Stewart, Jeremy; Herbst, John; Weller, Harold N

    2010-12-30

    Quantification of small molecules using liquid chromatography/tandem mass spectrometry (LC/MS/MS) on a triple quadrupole mass spectrometer has become a common practice in bioanalytical support of in vitro adsorption, distribution, metabolism and excretion (ADME) screening. The bioanalysis process involves primarily three indispensable steps: MS/MS optimization for a large number of new chemical compounds undergoing various screening assays in early drug discovery, high-throughput sample analysis with LC/MS/MS for those chemically diverse compounds using the optimized MS/MS conditions, and post-acquisition data review and reporting. To improve overall efficiency of ADME bioanalysis, an integrated system was proposed featuring an automated and unattended MS/MS optimization, a staggered parallel LC/MS/MS for high-throughput sample analysis, and a sophisticated software tool for LC/MS/MS raw data review as well as biological data calculation and reporting. The integrated platform has been used in bioanalytical support of a serum protein binding screening assay with high speed, high capacity, and good robustness. In this new platform, a unique sample dilution scheme was also introduced. With this dilution design, the total number of analytical samples was reduced; therefore, the total operation time was reduced and the overall throughput was further improved. The performance of the protein binding screening assay was monitored with two controls representing high and low binding properties and an acceptable inter-assay consistency was achieved. This platform has been successfully used for the determination of serum protein binding in multiple species for more than 4000 compounds.

  1. RAPID: real-time analytics platform for interactive data-mining in a decision support scenario

    Science.gov (United States)

    Vanni, Michelle; Kase, Sue E.; Karunasekara, Shanika; Falzon, Lucia; Harwood, Aaron

    2017-05-01

    Real-time Analytics Platform for Interactive Data-mining (RAPID), a collaboration of University of Melbourne and Australia's Defense Science and Technology Group (DSTG), consumes data streams, performs analytics computations, and produces high-quality knowledge for analysts. RAPID takes topic seed words and autonomously identifies emerging keywords in the data. Users direct the system, setting time-windowing parameters, thresholds, update intervals and sample rates. Apache Storm and Apache Kafka permit real-time streaming while logging options support off-line processing. Decision-support scenarios feature Commander Critical Information Requirements involving comparisons over time and time-sequencing of events, capabilities particularly well-served by RAPID technology, to be demonstrated in the presentation.

  2. Towards a Common Platform to Support Business Processes, Services and Semantics

    Science.gov (United States)

    Piprani, Baba

    The search for the Holy Grail in achieving interoperability of business processes, services and semantics continues with every new type or search for the Silver Bullet. Most approaches towards interoperability either are focusing narrowly on the simplistic notion using technology supporting a cowboy-style development without much regard to metadata or semantics. At the same time, the distortions on semantics created by many of current modeling paradigms and approaches - including the disharmony created by multiplicity of parallel approaches to standardization - are not helping us resolve the real issues facing knowledge and semantics management. This paper will address some of the issues facing us, like: What have we achieved? Where did we go wrong? What are we doing right? - providing an ipso-facto encapsulated candid snapshot on an approach to harmonizing our approach to interoperability, and propose a common platform to support Business Processes, Services and Semantics.

  3. Tropical tephritid fruit fly community with high incidence of shared Wolbachia strains as platform for horizontal transmission of endosymbionts.

    Science.gov (United States)

    Morrow, J L; Frommer, M; Shearman, D C A; Riegler, M

    2014-12-01

    Wolbachia are endosymbiotic bacteria that infect 40-65% of arthropod species. They are primarily maternally inherited with occasional horizontal transmission for which limited direct ecological evidence exists. We detected Wolbachia in 8 out of 24 Australian tephritid species. Here, we have used multilocus sequence typing (MLST) to further characterize these Wolbachia strains, plus a novel quantitative polymerase chain reaction method for allele assignment in multiple infections. Based on five MLST loci and the Wolbachia surface protein gene (wsp), five Bactrocera and one Dacus species harboured two identical strains as double infections; furthermore, Bactrocera neohumeralis harboured both of these as single or double infections, and sibling species B. tryoni harboured one. Two Bactrocera species contained Wolbachia pseudogenes, potentially within the fruit fly genomes. A fruit fly parasitoid, Fopius arisanus shared identical alleles with two Wolbachia strains detected in one B. frauenfeldi individual. We report an unprecedented high incidence of four shared Wolbachia strains in eight host species from two trophic levels. This suggests frequent exposure to Wolbachia in this tropical tephritid community that shares host plant and parasitoid species, and also includes species that hybridize. Such insect communities may act as horizontal transmission platforms that contribute to the ubiquity of the otherwise maternally inherited Wolbachia.

  4. Prototype development of a web-based participative decision support platform in risk management

    Science.gov (United States)

    Aye, Zar Chi; Olyazadeh, Roya; Jaboyedoff, Michel; Derron, Marc-Henri

    2014-05-01

    This paper discusses the proposed background architecture and prototype development of an internet-based decision support system (DSS) in the field of natural hazards and risk management using open-source geospatial software and web technologies. It is based on a three-tier, client-server architecture with the support of boundless (opengeo) framework and its client side SDK application environment using customized gxp components and data utility classes. The main purpose of the system is to integrate the workflow of risk management systematically with the diverse involvement of stakeholders from different organizations dealing with natural hazards and risk for evaluation of management measures through the active online participation approach. It aims to develop an adaptive user friendly, web-based environment that allows the users to set up risk management strategies based on actual context and data by integrating web-GIS and DSS functionality associated with process flow and other visualization tools. Web-GIS interface has been integrated within the DSS to deliver maps and provide certain geo-processing capabilities on the web, which can be easily accessible and shared by different organizations located in case study sites of the project. This platform could be envisaged not only as a common web-based platform for the centralized sharing of data such as hazard maps, elements at risk maps and additional information but also to ensure an integrated platform of risk management where the users could upload data, analyze risk and identify possible alternative scenarios for risk reduction especially for floods and landslides, either quantitatively or qualitatively depending on the risk information provided by the stakeholders in case study regions. The level of involvement, access to and interaction with the provided functionality of the system varies depending on the roles and responsibilities of the stakeholders, for example, only the experts (planners, geological

  5. TRIO Platform: A novel low profile in vivo imaging support and restraint system for mice

    Directory of Open Access Journals (Sweden)

    Vladislav eVoziyanov

    2016-04-01

    Full Text Available High resolution, in vivo optical imaging of the mouse brain over time often requires anesthesia, which necessitates maintaining the animal's body temperature and level of anesthesia, as well as securing the head in an optimal, stable position. Controlling each parameter usually requires using multiple systems. Assembling multiple components into the small space on a standard microscope stage can be difficult and some commercially available parts simply do not fit. Furthermore, it is time-consuming to position an animal in the identical position over multiple imaging sessions for longitudinal studies. This is especially true when using an implanted gradient index (GRIN lens for deep brain imaging. The multiphoton laser beam must be parallel with the shaft of the lens because even a slight tilt of the lens can degrade image quality. In response to these challenges, we have designed a compact, integrated in vivo imaging support system to overcome the problems created by using separate systems during optical imaging in mice. It is a single platform that provides (1 sturdy head fixation, (2 an integrated gas anesthesia mask, and (3 safe warm water heating. This THREE-IN-ONE (TRIO Platform has a small footprint and a low profile that positions a mouse’s head only 20 mm above the microscope stage. This height is about one half to one third the height of most commercially available immobilization devices. We have successfully employed this system, using isoflurane in over 40 imaging sessions with an average of 2 h per session with no leaks or other malfunctions. Due to its smaller size, the TRIO Platform can be used with a wider range of upright microscopes and stages. Most of the components were designed in SOLIDWORKS® and fabricated using a 3D printer. This additive manufacturing approach also readily permits size modifications for creating systems for other small animals.

  6. TRIO Platform: A Novel Low Profile In vivo Imaging Support and Restraint System for Mice.

    Science.gov (United States)

    Voziyanov, Vladislav; Kemp, Benjamin S; Dressel, Chelsea A; Ponder, Kayla; Murray, Teresa A

    2016-01-01

    High resolution, in vivo optical imaging of the mouse brain over time often requires anesthesia, which necessitates maintaining the animal's body temperature and level of anesthesia, as well as securing the head in an optimal, stable position. Controlling each parameter usually requires using multiple systems. Assembling multiple components into the small space on a standard microscope stage can be difficult and some commercially available parts simply do not fit. Furthermore, it is time-consuming to position an animal in the identical position over multiple imaging sessions for longitudinal studies. This is especially true when using an implanted gradient index (GRIN) lens for deep brain imaging. The multiphoton laser beam must be parallel with the shaft of the lens because even a slight tilt of the lens can degrade image quality. In response to these challenges, we have designed a compact, integrated in vivo imaging support system to overcome the problems created by using separate systems during optical imaging in mice. It is a single platform that provides (1) sturdy head fixation, (2) an integrated gas anesthesia mask, and (3) safe warm water heating. This THREE-IN-ONE (TRIO) Platform has a small footprint and a low profile that positions a mouse's head only 20 mm above the microscope stage. This height is about one half to one third the height of most commercially available immobilization devices. We have successfully employed this system, using isoflurane in over 40 imaging sessions with an average of 2 h per session with no leaks or other malfunctions. Due to its smaller size, the TRIO Platform can be used with a wider range of upright microscopes and stages. Most of the components were designed in SOLIDWORKS® and fabricated using a 3D printer. This additive manufacturing approach also readily permits size modifications for creating systems for other small animals.

  7. Family-supportive work environments and psychological strain: a longitudinal test of two theories.

    Science.gov (United States)

    Odle-Dusseau, Heather N; Herleman, Hailey A; Britt, Thomas W; Moore, Dewayne D; Castro, Carl A; McGurk, Dennis

    2013-01-01

    Based on the Job Demands-Resources (JDR) model (E. Demerouti, A. B. Bakker, F. Nachreiner, & W. B. Schaufeli, 2001, The job demands-resources model of burnout. Journal of Applied Psychology, 86, 499-512) and Conservation of Resources (COR) theory (S. E. Hobfoll, 2002, Social and psychological resources and adaptation. Review of General Psychology, 6, 307-324), we tested three competing models that predict different directions of causation for relationships over time between family-supportive work environments (FSWE) and psychological strain, with two waves of data from a military sample. Results revealed support for both the JDR and COR theories, first in the static model where FSWE at Time 1 predicted psychological strain at Time 2 and when testing the opposite direction, where psychological strain at Time 1 predicted FSWE at Time 2. For change models, FSWE predicted changes in psychological strain across time, although the reverse causation model was not supported (psychological strain at Time 1 did not predict changes in FSWE). Also, changes in FSWE across time predicted psychological strain at Time 2, whereas changes in psychological strain did not predict FSWE at Time 2. Theoretically, these results are important for the work-family interface in that they demonstrate the application of a systems approach to studying work and family interactions, as support was obtained for both the JDR model with perceptions of FSWE predicting psychological strain (in both the static and change models), and for COR theory where psychological strain predicts FSWE across time.

  8. Open Support Platform for Environmental Research (OSPER) - tools for the discovery and exploitation of environmental data

    Science.gov (United States)

    Dawes, N. M.; Lehning, M.; Bavay, M.; Sarni, S.; Iosifescu, I.; Gwadera, R.; Scipion, D. E.; Blanchet, J.; Davison, A.; Berne, A.; Hurni, L.; Parlange, M. B.; Aberer, K.

    2012-12-01

    The Open Support Platform for Environmental Research (OSPER) has been launched to take forward key data management components developed under the Swiss Experiment platform project to achieve improved usability and a wider scope. With this project, we aim to connect users to data and their context, an area identified during SwissEx as having the greatest potential impact on the research community. OSPER has a clear focus on providing the technology for data storage, management and exploitation with a special focus on data interoperability and documentation. In this presentation, we will demonstrate the key aims of OSPER for the period 2012 - 2015. Inheriting the basic SwissEx functionality, OSPER provides an excellent method of making data accessible via their metadata. One of the biggest differences between the OSPER infrastructure and other data platforms is the level of interaction that one can have with the data and the level of integration with the analysis tools used in science. We wish to capitalise on this advantage by increasing this integration and working with environmental research projects to develop the tools that make a difference to their daily research. The new data infrastructure will serve the following purposes: ● Open documentation, archiving and discovery of datasets. ● Facilitation of data sharing and collaboration (especially inter-disciplinary) with data owner controlled access rights, particularly concentrating on providing as much contextual information as possible. ● Improvements in ease of data access and combination of data sources. ● Tools for data visualisation and statistical and numerical data analysis with a focus on spatial data and trends. Key areas identified for development during OSPER are: ● New infrastructure and content for current WebGIS-based data visualisation system to create a publicly available platform. ● Provision of data in standard formats using standard methods as well as the consumption of such data

  9. A Collaborative Platform to Support the Enterprise 2.0 in Active Interactions with Customers

    Directory of Open Access Journals (Sweden)

    Domenico CONSOLI

    2012-01-01

    Full Text Available In recent years a new model of Enterprise 2.0, which interacts actively with customers using web 2.0 tools (chat, forum, blog, wiki, is developing. The enterprises, listening opinions and suggestions of customers, can improve the product/service. For a company, customer's opinions are very important both for the improvement of products and also for the reinforcement of the customer loyalty. The customer will be motivated to be loyal if the enterprise shows a strong attention to his/her needs. This paper presents a model of a collaborative and interactive platform that supports the Enterprise 2.0 in the management of communications and relationships with all stakeholder of the supply chain and in particular with customers. A good e-reputation of the company improves business performances.

  10. Probing peptide and protein insertion in a biomimetic S-layer supported lipid membrane platform.

    Science.gov (United States)

    Damiati, Samar; Schrems, Angelika; Sinner, Eva-Kathrin; Sleytr, Uwe B; Schuster, Bernhard

    2015-01-27

    The most important aspect of synthetic lipid membrane architectures is their ability to study functional membrane-active peptides and membrane proteins in an environment close to nature. Here, we report on the generation and performance of a biomimetic platform, the S-layer supported lipid membrane (SsLM), to investigate the structural and electrical characteristics of the membrane-active peptide gramicidin and the transmembrane protein α-hemolysin in real-time using a quartz crystal microbalance with dissipation monitoring in combination with electrochemical impedance spectroscopy. A shift in membrane resistance is caused by the interaction of α-hemolysin and gramicidin with SsLMs, even if only an attachment onto, or functional channels through the lipid membrane, respectively, are formed. Moreover, the obtained results did not indicate the formation of functional α-hemolysin pores, but evidence for functional incorporation of gramicidin into this biomimetic architecture is provided.

  11. An Internet of Things platform architecture for supporting ambient assisted living environments.

    Science.gov (United States)

    Tsirmpas, Charalampos; Kouris, Ioannis; Anastasiou, Athanasios; Giokas, Kostas; Iliopoulou, Dimitra; Koutsouris, Dimitris

    2017-01-01

    Internet of Things (IoT) is the logical further development of today's Internet, enabling a huge amount of devices to communicate, compute, sense and act. IoT sensors placed in Ambient Assisted Living (AAL) environments, enable the context awareness and allow the support of the elderly in their daily routines, ultimately allowing an independent and safe lifestyle. The vast amount of data that are generated and exchanged between the IoT nodes require innovative context modeling approaches that go beyond currently used models. Current paper presents and evaluates an open interoperable platform architecture in order to utilize the technical characteristics of IoT and handle the large amount of generated data, as a solution to the technical requirements of AAL applications.

  12. Strain-Induced Water Dissociation on Supported Ultrathin Oxide Films

    CERN Document Server

    Song, Zhenjun; Xu, Hu

    2015-01-01

    Controlling the dissociation of single water molecule on an insulating surface plays a crucial role in many catalytic reactions. In this Letter, we have identified the enhanced chemical reactivity of ultrathin MgO(100) films deposited on Mo(100) substrate that causes water dissociation. We reveal that the ability to split water on insulating surface closely depends on the lattice mismatch between ultrathin films and the underlying substrate, and substrate-induced in-plane tensile strain dramatically results in water dissociation on MgO(100). Three dissociative adsorption configurations of water with lower energy are predicted, and the structural transition going from molecular form to dissociative form is almost barrierless. Our results provide an effective avenue to achieve water dissociation at the single-molecule level and shed light on how to tune the chemical reactions of insulating surfaces by choosing the suitable substrates.

  13. Introducing StatHand: A cross-platform mobile application to support students’ statistical decision making

    Directory of Open Access Journals (Sweden)

    Peter James Allen

    2016-02-01

    Full Text Available Although essential to professional competence in psychology, quantitative research methods are a known area of weakness for many undergraduate psychology students. Students find selecting appropriate statistical tests and procedures for different types of research questions, hypotheses and data types particularly challenging, and these skills are not often practiced in class. Decision trees (a type of graphic organizer are known to facilitate this decision making process, but extant trees have a number of limitations. Furthermore, emerging research suggests that mobile technologies offer many possibilities for facilitating learning. It is within this context that we have developed StatHand, a free cross-platform application designed to support students’ statistical decision making. Developed with the support of the Australian Government Office for Learning and Teaching, StatHand guides users through a series of simple, annotated questions to help them identify a statistical test or procedure appropriate to their circumstances. It further offers the guidance necessary to run these tests and procedures, then interpret and report their results. In this Technology Report we will overview the rationale behind StatHand, before describing the feature set of the application. We will then provide guidelines for integrating StatHand into the research methods curriculum, before concluding by outlining our road map for the ongoing development and evaluation of StatHand.

  14. Introducing StatHand: A Cross-Platform Mobile Application to Support Students’ Statistical Decision Making

    Science.gov (United States)

    Allen, Peter J.; Roberts, Lynne D.; Baughman, Frank D.; Loxton, Natalie J.; Van Rooy, Dirk; Rock, Adam J.; Finlay, James

    2016-01-01

    Although essential to professional competence in psychology, quantitative research methods are a known area of weakness for many undergraduate psychology students. Students find selecting appropriate statistical tests and procedures for different types of research questions, hypotheses and data types particularly challenging, and these skills are not often practiced in class. Decision trees (a type of graphic organizer) are known to facilitate this decision making process, but extant trees have a number of limitations. Furthermore, emerging research suggests that mobile technologies offer many possibilities for facilitating learning. It is within this context that we have developed StatHand, a free cross-platform application designed to support students’ statistical decision making. Developed with the support of the Australian Government Office for Learning and Teaching, StatHand guides users through a series of simple, annotated questions to help them identify a statistical test or procedure appropriate to their circumstances. It further offers the guidance necessary to run these tests and procedures, then interpret and report their results. In this Technology Report we will overview the rationale behind StatHand, before describing the feature set of the application. We will then provide guidelines for integrating StatHand into the research methods curriculum, before concluding by outlining our road map for the ongoing development and evaluation of StatHand. PMID:26973579

  15. Escherichia coli W as a new platform strain for the enhanced production of L-valine by systems metabolic engineering.

    Science.gov (United States)

    Park, Jin Hwan; Jang, Yu-Sin; Lee, Jeong Wook; Lee, Sang Yup

    2011-05-01

    A less frequently employed Escherichia coli strain W, yet possessing useful metabolic characteristics such as less acetic acid production and high L-valine tolerance, was metabolically engineered for the production of L-valine. The ilvA gene was deleted to make more pyruvate, a key precursor for L-valine, available for enhanced L-valine biosynthesis. The lacI gene was deleted to allow constitutive expression of genes under the tac or trc promoter. The ilvBN(mut) genes encoding feedback-resistant acetohydroxy acid synthase (AHAS) I and the L-valine biosynthetic ilvCED genes encoding acetohydroxy acid isomeroreductase, dihydroxy acid dehydratase, and branched chain amino acid aminotransferase, respectively, were amplified by plasmid-based overexpression. The global regulator Lrp and L-valine exporter YgaZH were also amplified by plasmid-based overexpression. The engineered E. coli W (ΔlacI ΔilvA) strain overexpressing the ilvBN(mut) , ilvCED, ygaZH, and lrp genes was able to produce an impressively high concentration of 60.7 g/L L-valine by fed-batch culture in 29.5 h, resulting in a high volumetric productivity of 2.06 g/L/h. The most notable finding is that there was no other byproduct produced during L-valine production. The results obtained in this study suggest that E. coli W can be a good alternative to Corynebacterium glutamicum and E. coli K-12, which have so far been the most efficient L-valine producer. Furthermore, it is expected that various bioproducts including other amino acids might be more efficiently produced by this revisited platform strain of E. coli.

  16. Accessorizing Building Science – A Web Platform to Support Multiple Market Transformation Programs

    Energy Technology Data Exchange (ETDEWEB)

    Madison, Michael C.; Antonopoulos, Chrissi A.; Dowson, Scott T.; Franklin, Trisha L.; Carlsen, Leif C.; Baechler, Michael C.

    2014-09-28

    As demand for improved energy efficiency in homes increases, builders need information on the latest findings in building science, rapidly ramping-up energy codes, and technical requirements for labeling programs. The Building America Solution Center is a Department of Energy (DOE) website containing hundreds of expert guides designed to help residential builders install efficiency measures in new and existing homes. Builders can package measures with other media for customized content. Website content provides technical support to market transformation programs such as ENERGY STAR and has been cloned and adapted to provide content for the Better Buildings Residential Program. The Solution Center uses the Drupal open source content management platform to combine a variety of media in an interactive manner to make information easily accessible. Developers designed a unique taxonomy to organize and manage content. That taxonomy was translated into web-based modules that allow users to rapidly traverse structured content with related topics, and media. We will present information on the current design of the Solution Center and the underlying technology used to manage the content. The paper will explore development of features, such as “Field Kits” that allow users to bundle and save content for quick access, along with the ability to export PDF versions of content. Finally, we will discuss development of an Android based mobile application, and a visualization tool for interacting with Building Science Publications that allows the user to dynamically search the entire Building America Library.

  17. Embedded system in Arduino platform with Fuzzy control to support the grain aeration decision

    Directory of Open Access Journals (Sweden)

    Albino Szesz Junior

    Full Text Available ABSTRACT: Aeration is currently the most commonly used technique to improve the drying and storage of grain, depending on temperature and water content of the grain, as of the temperature and relative humidity of the outside air. In order to monitor temperature and humidity of the grain mass, it is possible to have a network of sensors in the cells of both internal and external storage. Use of artificial intelligence through Fuzzy theory, has been used since the 60s and enables their application on various forms. Thus, it is observed that the aeration of grain in function of representing a system of controlled environment can be studied in relation to the application of this theory. Therefore, the aim of this paper is to present an embedded Fuzzy control system based on the mathematical model of CRUZ et al. (2002 and applied to the Arduino platform, for decision support in aeration of grain. For this, an embedded Arduino system was developed, which received the environmental values of temperature and humidity to then be processed in a Fuzzy controller and return the output as a recommendation to control the aeration process rationally. Comparing the results obtained from the graph presented by LASSERAN (1981 it was observed that the system is effective.

  18. A Platform for Supporting Knowledge Mining and Reuse Based on Context Information of a Project

    Directory of Open Access Journals (Sweden)

    I-Chin Wu

    2010-06-01

    Full Text Available Organizations implement Knowledge Management Systems (KMS to maximize the effectiveness and reuse of knowledge assets in order to increase productivity and profitability. Thus, effective project management can place great demands on knowledge management solutions designed to support and streamline the execution of project-related tasks. Accordingly, in this work we extract knowledge from historical projects, design a project-in-context (PIC meta-model, and deploy a platform that facilitates the capture and reuse of project-specific information based on the context. The research areas addressed in the work are as follows. (1 Knowledge acquisition: analyzing the type of project and its associated attributes and defining general, but essential, project context information based on the PIC model. (2 Knowledge discovery: the use of text mining and data mining techniques to extract knowledge items needed by workers, and discover the relationships between various knowledge items. (3 Knowledge utilization based on the context: with the proposed model and methods, several applications related to the reuse of project knowledge by pull- and push-based knowledge management strategies are developed to achieve effective project management. From the perspective of project management, the proposed model and system can help knowledge workers understand information about a current research project and resolve problems effectively. [Article content in Chinese; Extended abstract in English

  19. A platform for testing and comparing of real-time decision-support algorithms in mobile environments.

    Science.gov (United States)

    Khitrov, Maxim Y; Rutishauser, Matthew; Montgomery, Kevin; Reisner, Andrew T; Reifman, Jaques

    2009-01-01

    The unavailability of a flexible system for realtime testing of decision-support algorithms in a pre-hospital clinical setting has limited their use. In this study, we describe a plug-and-play platform for real-time testing of decision-support algorithms during the transport of trauma casualties en route to a hospital. The platform integrates a standard-of-care vital-signs monitor, which collects numeric and waveform physiologic time-series data, with a rugged ultramobile personal computer. The computer time-stamps and stores data received from the monitor, and performs analysis on the collected data in real-time. Prior to field deployment, we assessed the performance of each component of the platform by using an emulator to simulate a number of possible fault scenarios that could be encountered in the field. Initial testing with the emulator allowed us to identify and fix software inconsistencies and showed that the platform can support a quick development cycle for real-time decision-support algorithms.

  20. Tethys: A Platform for Water Resources Modeling and Decision Support Apps

    Science.gov (United States)

    Nelson, J.; Swain, N. R.

    2015-12-01

    The interactive nature of web applications or "web apps" makes it an excellent medium for conveying complex scientific concepts to lay audiences and creating decision support tools that harness cutting edge modeling techniques. However, the technical expertise required to develop web apps represents a barrier for would-be developers. This barrier can be characterized by the following hurdles that developers must overcome: (1) identify, select, and install software that meet the spatial and computational capabilities commonly required for water resources modeling; (2) orchestrate the use of multiple free and open source (FOSS) projects and navigate their differing application programming interfaces; (3) learn the multi-language programming skills required for modern web development; and (4) develop a web-secure and fully featured web portal to host the app. Tethys Platform has been developed to lower the technical barrier and minimize the initial development investment that prohibits many scientists and engineers from making use of the web app medium. It includes (1) a suite of FOSS that address the unique data and computational needs common to water resources web app development, (2) a Python software development kit that streamlines development, and (3) a customizable web portal that is used to deploy the completed web apps. Tethys synthesizes several software projects including PostGIS, 52°North WPS, GeoServer, Google Maps™, OpenLayers, and Highcharts. It has been used to develop a broad array of web apps for water resources modeling and decision support for several projects including CI-WATER, HydroShare, and the National Flood Interoperability Experiment. The presentation will include live demos of some of the apps that have been developed using Tethys to demonstrate its capabilities.

  1. Is the association between high strain work and depressive symptoms modified by private life social support

    DEFF Research Database (Denmark)

    Madsen, Ida E H; Jorgensen, Anette F B; Borritz, Marianne

    2014-01-01

    ,074 Danish employees. At baseline, all participants were free of severe depressive symptoms, measured by the Mental Health Inventory. High strain work was defined by the combination of high psychological demands at work and low control, measured with multi-dimensional scales. Private life social support...... significant (p = 0.18). CONCLUSIONS: Our findings suggest that high strain work may increase risk of depressive symptoms in individuals with low private life social support, although the effect-modification was statistically non-significant. Larger studies are needed to further establish the role of private...... be modified by factors outside the working environment. This article examines the modifying role of private life social support in the relation between high strain work and the development of severe depressive symptoms. METHODS: Data were questionnaire-based, collected from a cross-occupational sample of 1...

  2. Effects of work burden, job strain and support on depressive symptoms and burnout among Japanese physicians

    Directory of Open Access Journals (Sweden)

    Yasuaki Saijo

    2014-12-01

    Full Text Available Objectives: Days off, on call, night duty, working hours and job stress can affect physicians’ mental health, and support from supervisors and co-workers may have a buffering effect. This study elucidates whether job strain and job factors affect physicians’ mental health, and whether support from supervisors and co-workers has a protective effect on their mental health. Material and Methods: The subjects included 494 physicians. The Brief Job Stress Questionnaire (BJSQ was used to evaluate job demand, job control and support. High job strain was defined as a combination of high job demand and low job control. Depressive symptoms were assessed using the Patient Health Questionnaire-9. The Maslach Burnout Inventory- General Survey was used to evaluate burnout. Possible confounder adjusted logistic regression analyses were performed to obtain odds ratios for depressive symptoms and burnout. Results: As per the analysis, high job strain had significantly higher odds ratios, and support from co-workers had significant protective odds ratios for depressive symptoms. High job strain and having only 2–4 days off per month (compared to > 8 days off per month had significantly higher odds ratios, and support from co-workers had significant protective odds ratios for burnout. Conclusions: High job strain was related to depressive symptoms and burnout, and support from co-workers had a buffering effect on depressive symptoms and burnout. An inadequate number of days off was related to burnout. Assessment of job strain may be a good tool to measure physicians’ mental health, and a sufficient number of days off may be needed to prevent burnout.

  3. Towards Supporting Climate Scientists and Impact Assessment Analysts with the Big Data Europe Platform

    Science.gov (United States)

    Klampanos, Iraklis; Vlachogiannis, Diamando; Andronopoulos, Spyros; Cofiño, Antonio; Charalambidis, Angelos; Lokers, Rob; Konstantopoulos, Stasinos; Karkaletsis, Vangelis

    2016-04-01

    The EU, Horizon 2020, project Big Data Europe (BDE) aims to support European companies and institutions in effectively managing and making use of big data in activities critical to their progress and success. BDE focuses on seven areas of societal impact: Health, Food and Agriculture, Energy, Transport, Climate, Social Sciences and Security. By reaching out to partners and stakeholders, BDE aims to elicit data-intensive requirements for, and deliver an ICT platform to cover aspects of publishing and consuming semantically interoperable, large-scale, multi-lingual data assets and knowledge. In this presentation we will describe the first BDE pilot for Climate, focusing on SemaGrow, its core component, which provides data querying and management based on data semantics. Over the last few decades, extended scientific effort in understanding climate change has resulted in a huge volume of model and observational data. Large international global and regional model inter-comparison projects have focused on creating a framework in support of climate model diagnosis, validation, documentation and data access. The application of climate model ensembles, a system consisting of different possible realisations of a climate model, has further significantly increased the amount of climate and weather data generated. The provision of such models satisfies the crucial objective of assessing potential impacts of climate change on well-being for adaptation, prevention and mitigation. One of the methodologies applied by the climate research and impact assessment communities is that of dynamical downscaling. This calculates values of atmospheric variables in smaller spatial and temporal scales, given a global model. On the company or institution level, this process can be greatly improved in terms of querying, data ingestion from various sources and formats, automatic data mapping, etc. The first Climate BDE pilot will facilitate the process of dynamical downscaling by providing a

  4. A draft genome of the brown alga, Cladosiphon okamuranus, S-strain: a platform for future studies of 'mozuku' biology.

    Science.gov (United States)

    Nishitsuji, Koki; Arimoto, Asuka; Iwai, Kenji; Sudo, Yusuke; Hisata, Kanako; Fujie, Manabu; Arakaki, Nana; Kushiro, Tetsuo; Konishi, Teruko; Shinzato, Chuya; Satoh, Noriyuki; Shoguchi, Eiichi

    2016-12-01

    The brown alga, Cladosiphon okamuranus (Okinawa mozuku), is economically one of the most important edible seaweeds, and is cultivated for market primarily in Okinawa, Japan. C. okamuranus constitutes a significant source of fucoidan, which has various physiological and biological activities. To facilitate studies of seaweed biology, we decoded the draft genome of C. okamuranus S-strain. The genome size of C. okamuranus was estimated as ∼140 Mbp, smaller than genomes of two other brown algae, Ectocarpus siliculosus and Saccharina japonica Sequencing with ∼100× coverage yielded an assembly of 541 scaffolds with N50 = 416 kbp. Together with transcriptomic data, we estimated that the C. okamuranus genome contains 13,640 protein-coding genes, approximately 94% of which have been confirmed with corresponding mRNAs. Comparisons with the E. siliculosus genome identified a set of C. okamuranus genes that encode enzymes involved in biosynthetic pathways for sulfated fucans and alginate biosynthesis. In addition, we identified C. okamuranus genes for enzymes involved in phlorotannin biosynthesis. The present decoding of the Cladosiphon okamuranus genome provides a platform for future studies of mozuku biology. © The Author 2016. Published by Oxford University Press on behalf of Kazusa DNA Research Institute.

  5. Eldercare Demands, Strain, and Work Engagement: The Moderating Role of Perceived Organizational Support

    Science.gov (United States)

    Zacher, Hannes; Winter, Gabriele

    2011-01-01

    Demographic changes give rise to an increasing number of middle-aged employees providing home-based care to an elderly family member. However, the potentially important role of employees' perceptions of organizational support for eldercare has so far not been investigated. The goal of this study was to examine a stressor-strain-outcome model…

  6. Eldercare Demands, Strain, and Work Engagement: The Moderating Role of Perceived Organizational Support

    Science.gov (United States)

    Zacher, Hannes; Winter, Gabriele

    2011-01-01

    Demographic changes give rise to an increasing number of middle-aged employees providing home-based care to an elderly family member. However, the potentially important role of employees' perceptions of organizational support for eldercare has so far not been investigated. The goal of this study was to examine a stressor-strain-outcome model…

  7. GeoProMT: A Collaborative Platform Supporting Natural Hazards Project Management From Assessment to Resilience

    Science.gov (United States)

    Renschler, C.; Sheridan, M. F.; Patra, A. K.

    2008-05-01

    The impact and consequences of extreme geophysical events (hurricanes, floods, wildfires, volcanic flows, mudflows, etc.) on properties and processes should be continuously assessed by a well-coordinated interdisciplinary research and outreach approach addressing risk assessment and resilience. Communication between various involved disciplines and stakeholders is the key to a successful implementation of an integrated risk management plan. These issues become apparent at the level of decision support tools for extreme events/disaster management in natural and managed environments. The Geospatial Project Management Tool (GeoProMT) is a collaborative platform for research and training to document and communicate the fundamental steps in transforming information for extreme events at various scales for analysis and management. GeoProMT is an internet-based interface for the management of shared geo-spatial and multi-temporal information such as measurements, remotely sensed images, and other GIS data. This tool enhances collaborative research activities and the ability to assimilate data from diverse sources by integrating information management. This facilitates a better understanding of natural processes and enhances the integrated assessment of resilience against both the slow and fast onset of hazard risks. Fundamental to understanding and communicating complex natural processes are: (a) representation of spatiotemporal variability, extremes, and uncertainty of environmental properties and processes in the digital domain, (b) transformation of their spatiotemporal representation across scales (e.g. interpolation, aggregation, disaggregation.) during data processing and modeling in the digital domain, and designing and developing tools for (c) geo-spatial data management, and (d) geo-spatial process modeling and effective implementation, and (e) supporting decision- and policy-making in natural resources and hazard management at various spatial and temporal scales

  8. Tethys: A Platform for Water Resources Modeling and Decision Support Apps

    Science.gov (United States)

    Swain, N. R.; Christensen, S. D.; Jones, N.; Nelson, E. J.

    2014-12-01

    Cloud-based applications or apps are a promising medium through which water resources models and data can be conveyed in a user-friendly environment—making them more accessible to decision-makers and stakeholders. In the context of this work, a water resources web app is a web application that exposes limited modeling functionality for a scenario exploration activity in a structured workflow (e.g.: land use change runoff analysis, snowmelt runoff prediction, and flood potential analysis). The technical expertise required to develop water resources web apps can be a barrier to many potential developers of water resources apps. One challenge that developers face is in providing spatial storage, analysis, and visualization for the spatial data that is inherent to water resources models. The software projects that provide this functionality are non-standard to web development and there are a large number of free and open source software (FOSS) projects to choose from. In addition, it is often required to synthesize several software projects to provide all of the needed functionality. Another challenge for the developer will be orchestrating the use of several software components. Consequently, the initial software development investment required to deploy an effective water resources cloud-based application can be substantial. The Tethys Platform has been developed to lower the technical barrier and minimize the initial development investment that prohibits many scientists and engineers from making use of the web app medium. Tethys synthesizes several software projects including PostGIS for spatial storage, 52°North WPS for spatial analysis, GeoServer for spatial publishing, Google Earth™, Google Maps™ and OpenLayers for spatial visualization, and Highcharts for plotting tabular data. The software selection came after a literature review of software projects being used to create existing earth sciences web apps. All of the software is linked via a Python

  9. Senior management leadership, social support, job design and stressor-to-strain relationships in hospital practice.

    Science.gov (United States)

    Buttigieg, Sandra C; West, Michael A

    2013-01-01

    The purpose of this paper is to examine the effect of the quality of senior management leadership on social support and job design, whose main effects on strains, and moderating effects on work stressors-to-strains relationships were assessed. A survey involving distribution of questionnaires was carried out on a random sample of health care employees in acute hospital practice in the UK. The sample comprised 65,142 respondents. The work stressors tested were quantitative overload and hostile environment, whereas strains were measured through job satisfaction and turnover intentions. Structural equation modelling and moderated regression analyses were used in the analysis. Quality of senior management leadership explained 75 per cent and 94 per cent of the variance of social support and job design respectively, whereas work stressors explained 51 per cent of the variance of strains. Social support and job design predicted job satisfaction and turnover intentions, as well as moderated significantly the relationships between quantitative workload/hostility and job satisfaction/turnover intentions. The findings are useful to management and to health employees working in acute/specialist hospitals. Further research could be done in other counties to take into account cultural differences and variations in health systems. The limitations included self-reported data and percept-percept bias due to same source data collection. The quality of senior management leaders in hospitals has an impact on the social environment, the support given to health employees, their job design, as well as work stressors and strains perceived. The study argues in favour of effective senior management leadership of hospitals, as well as ensuring adequate support structures and job design. The findings may be useful to health policy makers and human resources managers.

  10. Spousal social support and strain: impacts on health in older couples.

    Science.gov (United States)

    Ryan, Lindsay H; Wan, Wylie H; Smith, Jacqui

    2014-12-01

    Using a nationally representative sample of couples aged 51+ in the United States (N = 1,923 couples), the current study investigated whether both partners' perceptions of relationship support and strain are associated with an individual's self-rated health and functional limitations. The sample had an average age of 67.17 years (SD = 9.0; range 50-97). Actor-Partner Interdependence Models adjusting for couple interdependencies were applied using multilevel models. After accounting for age, education, gender, race, and couple differences in length of marriage, results indicate that individual perceptions of support were significantly associated with higher self-rated health and fewer functional limitations. These individual-level benefits increased if the spouse also perceived positive support and low strain. Finally, the negative association of an individual's perceived support on functional limitations was greater in those with a spouse reporting low levels of perceived strain. Findings are discussed relative to theory on behavioral and psychological pathways between partners' perceptions of support and health.

  11. Governance to support multi-use platforms at sea: recommendations from discourse analysis

    NARCIS (Netherlands)

    Burg, van den S.W.K.; Rammelt, T.; Stuiver, M.

    2015-01-01

    There is growing focus on multi-functional use of the marine environment. The solution presented is to combine
    different economic activities in ‘multi-use platforms at sea’ (MUPS). An expanding body of literature focusses on
    the economic, technical or social challenges that follow from combi

  12. Geospatial Analysis Platform and tools: supporting planning and decision making across scales, borders, sectors and disciplines

    CSIR Research Space (South Africa)

    Naude, AH

    2008-04-01

    Full Text Available The paper will (1) build an argument for the importance and challenges of connecting across scales and borders and between sectors, (2) provide a brief overview of GAP2 in terms of its geo-spatial analysis platform, the way in which it facilitates...

  13. Immune response to Bifidobacterium bifidum strains support Treg/Th17 plasticity.

    Directory of Open Access Journals (Sweden)

    Patricia López

    Full Text Available In this work we analyzed the immune activation properties of different Bifidobacterium strains in order to establish their ability as inductors of specific effector (Th or regulatory (Treg responses. First, we determined the cytokine pattern induced by 21 Bifidobacterium strains in peripheral blood mononuclear cells (PBMCs. Results showed that four Bifidobacterium bifidum strains showed the highest production of IL-17 as well as a poor secretion of IFNγ and TNFα, suggesting a Th17 profile whereas other Bifidobacterium strains exhibited a Th1-suggestive profile. Given the key role of Th17 subsets in mucosal defence, strains suggestive of Th17 responses and the putative Th1 Bifidobacterium breve BM12/11 were selected to stimulate dendritic cells (DC to further determine their capability to induce the differentiation of naïve CD4(+ lymphocytes toward different Th or Treg cells. All selected strains were able to induce phenotypic DC maturation, but showed differences in cytokine stimulation, DC treated with the putative Th17 strains displaying high IL-1β/IL-12 and low IL-12/IL-10 index, whereas BM12/11-DC exhibited the highest IL-12/IL-10 ratio. Differentiation of naïve lymphocytes confirmed Th1 polarization by BM12/11. Unexpectedly, any B. bifidum strain showed significant capability for Th17 generation, and they were able to generate functional Treg, thus suggesting differences between in vivo and vitro responses. In fact, activation of memory lymphocytes present in PBMCS with these bacteria, point out the presence in vivo of specific Th17 cells, supporting the plasticity of Treg/Th17 populations and the key role of commensal bacteria in mucosal tolerance and T cell reprogramming when needed.

  14. Ultra-Precision Measurement and Control of Angle Motion in Piezo-Based Platforms Using Strain Gauge Sensors and a Robust Composite Controller

    Directory of Open Access Journals (Sweden)

    Zhi-Gang Wu

    2013-07-01

    Full Text Available The measurement and control strategy of a piezo-based platform by using strain gauge sensors (SGS and a robust composite controller is investigated in this paper. First, the experimental setup is constructed by using a piezo-based platform, SGS sensors, an AD5435 platform and two voltage amplifiers. Then, the measurement strategy to measure the tip/tilt angles accurately in the order of sub-μrad is presented. A comprehensive composite control strategy design to enhance the tracking accuracy with a novel driving principle is also proposed. Finally, an experiment is presented to validate the measurement and control strategy. The experimental results demonstrate that the proposed measurement and control strategy provides accurate angle motion with a root mean square (RMS error of 0.21 μrad, which is approximately equal to the noise level.

  15. Ultra-precision measurement and control of angle motion in piezo-based platforms using strain gauge sensors and a robust composite controller.

    Science.gov (United States)

    Liu, Lei; Bai, Yu-Guang; Zhang, Da-Li; Wu, Zhi-Gang

    2013-07-15

    The measurement and control strategy of a piezo-based platform by using strain gauge sensors (SGS) and a robust composite controller is investigated in this paper. First, the experimental setup is constructed by using a piezo-based platform, SGS sensors, an AD5435 platform and two voltage amplifiers. Then, the measurement strategy to measure the tip/tilt angles accurately in the order of sub-μrad is presented. A comprehensive composite control strategy design to enhance the tracking accuracy with a novel driving principle is also proposed. Finally, an experiment is presented to validate the measurement and control strategy. The experimental results demonstrate that the proposed measurement and control strategy provides accurate angle motion with a root mean square (RMS) error of 0.21 μrad, which is approximately equal to the noise level.

  16. Using crosslinkable diacetylene phospholipids to construct two-dimensional packed beds in supported lipid bilayer separation platforms

    Directory of Open Access Journals (Sweden)

    Shu-Kai Hu, Sheng-Wen Hsiao, Hsun-Yen Mao, Ya-Ming Chen, Yung Chang and Ling Chao

    2013-01-01

    Full Text Available Separating and purifying cell membrane-associated biomolecules has been a challenge owing to their amphiphilic property. Taking these species out of their native lipid membrane environment usually results in biomolecule degradation. One of the new directions is to use supported lipid bilayer (SLB platforms to separate the membrane species while they are protected in their native environment. Here we used a type of crosslinkable diacetylene phospholipids, diynePC (1,2-bis(10,12-tricosadiynoyl-sn-glycero-3-phosphocholine, as a packed material to create a 'two-dimensional (2D packed bed' in a SLB platform. After the diynePC SLB is exposed to UV light, some of the diynePC lipids in the SLB can crosslink and the non-crosslinked monomer lipids can be washed away, leaving a 2D porous solid matrix. We incorporated the lipid vesicle deposition method with a microfluidic device to pattern the location of the packed-bed region and the feed region with species to be separated in a SLB platform. Our atomic force microscopy result shows that the nano-scaled structure density of the '2D packed bed' can be tuned by the UV dose applied to the diynePC membrane. When the model membrane biomolecules were forced to transport through the packed-bed region, their concentration front velocities were found to decrease linearly with the UV dose, indicating the successful creation of packed obstacles in these 2D lipid membrane separation platforms.

  17. CFGP 2.0: a versatile web-based platform for supporting comparative and evolutionary genomics of fungi and Oomycetes.

    Science.gov (United States)

    Choi, Jaeyoung; Cheong, Kyeongchae; Jung, Kyongyong; Jeon, Jongbum; Lee, Gir-Won; Kang, Seogchan; Kim, Sangsoo; Lee, Yin-Won; Lee, Yong-Hwan

    2013-01-01

    In 2007, Comparative Fungal Genomics Platform (CFGP; http://cfgp.snu.ac.kr/) was publicly open with 65 genomes corresponding to 58 fungal and Oomycete species. The CFGP provided six bioinformatics tools, including a novel tool entitled BLASTMatrix that enables search homologous genes to queries in multiple species simultaneously. CFGP also introduced Favorite, a personalized virtual space for data storage and analysis with these six tools. Since 2007, CFGP has grown to archive 283 genomes corresponding to 152 fungal and Oomycete species as well as 201 genomes that correspond to seven bacteria, 39 plants and 105 animals. In addition, the number of tools in Favorite increased to 27. The Taxonomy Browser of CFGP 2.0 allows users to interactively navigate through a large number of genomes according to their taxonomic positions. The user interface of BLASTMatrix was also improved to facilitate subsequent analyses of retrieved data. A newly developed genome browser, Seoul National University Genome Browser (SNUGB), was integrated into CFGP 2.0 to support graphical presentation of diverse genomic contexts. Based on the standardized genome warehouse of CFGP 2.0, several systematic platforms designed to support studies on selected gene families have been developed. Most of them are connected through Favorite to allow of sharing data across the platforms.

  18. Construction of the large-scale mining area decision-making support and the synthesis management platform

    Science.gov (United States)

    Wang, Shudong; Japper, Guli; Wang, Xiaohua

    2006-10-01

    Because of lacking modern information management and long-term planning, many serious problems, including environment, ecology, production and so forth, are found in Chinese large-scale, mid-scale and small-scale mining areas. GIS (Geographic Information System) can efficiently show its vital energies in problem solving, and which mainly depends on its powerful spatial analysis, decision-making and mass data storage and management ability. In this paper, we take large-scale mining area as an example to study GIS decision-making support, synthesis management platform applied mining area. According to characteristics of the large-scale mining area, we put forward a plan for GIS platform of information management and long-term planning of mining area: the platform is divided into decision support subsystem and the community synthesis management subsystem. The former includes following items: (1) Site selection, which is mainly for site selection of industrial production, commercial run and residential area; (2) Monitoring of reclaimed land and ecology, which is mainly for destructed field surface and subsurface of the mining area because of coal mining; (3) The synthesis management system of green mining, mainly for safety, efficiency and environment protection. The later, community synthesis management subsystem mainly includes: the community synthesis information subsystem and the public urgent predetermined planning subsystem. At last, some problems and shortages are analyzed in the system construction of the large-scale mining area.

  19. How Social-Media Enhanced Learning Platforms Support Students in Taking Responsibility for Their Own Learning

    DEFF Research Database (Denmark)

    Pals Svendsen, Lisbet; Mondahl, Margrethe

    2013-01-01

    Purpose – The paper is based on the chapter “How Social Media Enhanced Learning Platforms Challenge and Motivate Students to Take Charge of Their Own Learning Processes – A Few Examples” from the publication Increasing Student Engagement and Retention using Social Technologies: Facebook, e...... and how social media enhanced learning platforms challenge and motivate students in their learning processes. Findings – The paper provides examples from didactic experiments carried out at the Copenhagen Business School and in Danish high schools. The authors focus on the changing role of teachers from......-Portfolios and other Social Networking Services and on the authors’ research on ICT and social media enhanced learning in the foreign language/intercultural learning high school and university environment. Design/methodology/approach – The paper discusses learning in general and didactic practices in the two sectors...

  20. Biomechanics of longitudinal arch support mechanisms in foot orthoses and their effect on plantar aponeurosis strain.

    Science.gov (United States)

    Kogler, G F; Solomonidis, S E; Paul, J P

    1996-07-01

    OBJECTIVE: The purpose of this investigation was to quantify the longitudinal arch support properties of several types of foot orthosis. DESIGN: An in vitro method that simulated 'static stance' was used to determine arch support capabilities, with plantar aponeurosis strain implemented as the performance measure. BACKGROUND: A longitudinal arch support mechanism of an orthosis resists depression of the foot's arches by transferring a portion of the load to the medial structures of the foot. Since the plantar aponeurosis is in tension when the foot is loaded, a quantifiable decrease in strain should occur with an adequate orthotic arch control mechanism. METHODS: A differential variable reluctance transducer was surgically implanted in the plantar aponeurosis of cadaveric donor limb feet (n = 7). Each specimen was mounted in an electromechanical test machine which applied a load of up to 900 N axially to the tibia. The test schedule was divided into seven test conditions: specimen barefoot; specimen with shoe and specimen with shoe and five different orthoses. RESULTS: The University of California Biomechanics Laboratory Shoe Insert and two other foot orthoses significantly decreased the strain in the plantar aponeurosis compared to the barefoot control and were considered effective arch supports (P plantar aponeurosis strain. Significant variations of time required to achieve the specified load levels were recorded among the test conditions, indicating the relative cushioning properties of the shoe/orthosis systems. CONCLUSIONS: The patterns of plantar aponeurosis strain observed in cadaveric tests suggest that certain types of orthoses are more effective than others in the support of the foot's longitudinal arches. It is suggested that to support the longitudinal arches of the foot effectively the medial surface contours of the orthosis must stabilize the apical bony structure of the foot's arch. RELEVANCE: Reducing tension in the plantar aponeurosis is an

  1. Website Resource Monitoring Platform Supporting Tibetan and Uyghur Language based on Semantics

    Directory of Open Access Journals (Sweden)

    Lirong Qiu

    2013-08-01

    Full Text Available With the development of the Internet and the increasing minority language websites, people of ethnic minorities begin to browse the news, comments and other content on the Internet according to their own interests. At present, there is still no websites to provide the Chinese–Tibetan or Chinese-Uyghur co-occurrence search engine in China. In this paper, a platform for Tibetan and Uyghur website monitoring is proposed. The functions and characterizes are proposed in detail.

  2. A methodology towards virtualisation-based high performance simulation platform supporting multidisciplinary design of complex products

    Science.gov (United States)

    Ren, Lei; Zhang, Lin; Tao, Fei; (Luke) Zhang, Xiaolong; Luo, Yongliang; Zhang, Yabin

    2012-08-01

    Multidisciplinary design of complex products leads to an increasing demand for high performance simulation (HPS) platforms. One great challenge is how to achieve high efficient utilisation of large-scale simulation resources in distributed and heterogeneous environments. This article reports a virtualisation-based methodology to realise a HPS platform. This research is driven by the issues concerning large-scale simulation resources deployment and complex simulation environment construction, efficient and transparent utilisation of fine-grained simulation resources and high reliable simulation with fault tolerance. A framework of virtualisation-based simulation platform (VSIM) is first proposed. Then the article investigates and discusses key approaches in VSIM, including simulation resources modelling, a method to automatically deploying simulation resources for dynamic construction of system environment, and a live migration mechanism in case of faults in run-time simulation. Furthermore, the proposed methodology is applied to a multidisciplinary design system for aircraft virtual prototyping and some experiments are conducted. The experimental results show that the proposed methodology can (1) significantly improve the utilisation of fine-grained simulation resources, (2) result in a great reduction in deployment time and an increased flexibility for simulation environment construction and (3)achieve fault tolerant simulation.

  3. ERMHAN: A Context-Aware Service Platform to Support Continuous Care Networks for Home-Based Assistance.

    Science.gov (United States)

    Paganelli, Federica; Spinicci, Emilio; Giuli, Dino

    2008-01-01

    Continuous care models for chronic diseases pose several technology-oriented challenges for home-based continuous care, where assistance services rely on a close collaboration among different stakeholders such as health operators, patient relatives, and social community members. Here we describe Emilia Romagna Mobile Health Assistance Network (ERMHAN) a multichannel context-aware service platform designed to support care networks in cooperating and sharing information with the goal of improving patient quality of life. In order to meet extensibility and flexibility requirements, this platform has been developed through ontology-based context-aware computing and a service oriented approach. We also provide some preliminary results of performance analysis and user survey activity.

  4. ERMHAN: A Context-Aware Service Platform to Support Continuous Care Networks for Home-Based Assistance

    Directory of Open Access Journals (Sweden)

    Federica Paganelli

    2008-01-01

    Full Text Available Continuous care models for chronic diseases pose several technology-oriented challenges for home-based continuous care, where assistance services rely on a close collaboration among different stakeholders such as health operators, patient relatives, and social community members. Here we describe Emilia Romagna Mobile Health Assistance Network (ERMHAN a multichannel context-aware service platform designed to support care networks in cooperating and sharing information with the goal of improving patient quality of life. In order to meet extensibility and flexibility requirements, this platform has been developed through ontology-based context-aware computing and a service oriented approach. We also provide some preliminary results of performance analysis and user survey activity.

  5. Launching a virtual decision lab: development and field-testing of a web-based patient decision support research platform.

    Science.gov (United States)

    Hoffman, Aubri S; Llewellyn-Thomas, Hilary A; Tosteson, Anna N A; O'Connor, Annette M; Volk, Robert J; Tomek, Ivan M; Andrews, Steven B; Bartels, Stephen J

    2014-12-12

    Over 100 trials show that patient decision aids effectively improve patients' information comprehension and values-based decision making. However, gaps remain in our understanding of several fundamental and applied questions, particularly related to the design of interactive, personalized decision aids. This paper describes an interdisciplinary development process for, and early field testing of, a web-based patient decision support research platform, or virtual decision lab, to address these questions. An interdisciplinary stakeholder panel designed the web-based research platform with three components: a) an introduction to shared decision making, b) a web-based patient decision aid, and c) interactive data collection items. Iterative focus groups provided feedback on paper drafts and online prototypes. A field test assessed a) feasibility for using the research platform, in terms of recruitment, usage, and acceptability; and b) feasibility of using the web-based decision aid component, compared to performance of a videobooklet decision aid in clinical care. This interdisciplinary, theory-based, patient-centered design approach produced a prototype for field-testing in six months. Participants (n = 126) reported that: the decision aid component was easy to use (98%), information was clear (90%), the length was appropriate (100%), it was appropriately detailed (90%), and it held their interest (97%). They spent a mean of 36 minutes using the decision aid and 100% preferred using their home/library computer. Participants scored a mean of 75% correct on the Decision Quality, Knowledge Subscale, and 74 out of 100 on the Preparation for Decision Making Scale. Completing the web-based decision aid reduced mean Decisional Conflict scores from 31.1 to 19.5 (p platform that was feasible for use in research studies in terms of recruitment, acceptability, and usage. Within this platform, the web-based decision aid component performed comparably with the videobooklet

  6. Virtual environments in cancer care: Pilot-testing a three-dimensional web-based platform as a tool for support in young cancer patients

    DEFF Research Database (Denmark)

    Høybye, Mette Terp; Olsen, Pia Riis; Hansson, Helena Eva

    2016-01-01

    Bringing virtual environments into cancer support may offer a particular potential to engage patients and increase adherence to treatment. Developing and pilot-testing an online real-time multi-user three-dimensional platform, this study tested the use of an early prototype of the platform among...

  7. Interactive Generalization on Large-Scale Topographical Map Supported by a Database Platform

    Institute of Scientific and Technical Information of China (English)

    CAI Zhongliang; WU Hehai; DU Qingyun; LIAO Chujiang

    2003-01-01

    This paper makes astudy on the interactive digital gener-alization, where map generalizationcan be divided into intellective reason-ing procedure and operational proce-dure, which are done by human andcomputer, respectively. And an inter-active map generalization environmentfor large scale topographic map is thendesigned and realized. This researchfocuses on: ① the significance of re-searching an interactive map generali-zation environment, ② the features oflarge scale topographic map and inter-active map generalization, ③ the con-struction of map generalization-orien-ted database platform.

  8. Job strain and psychological distress among employed pregnant Thai women: role of social support and coping strategies.

    Science.gov (United States)

    Sanguanklin, Natthananporn; McFarlin, Barbara L; Finnegan, Lorna; Park, Chang Gi; Giurgescu, Carmen; White-Traut, Rosemary; Engstrom, Janet L

    2014-08-01

    Most Thai women continue to work throughout their pregnancy; however, little is known about job strain and its relation to psychological distress. This study aimed to examine: (1) the direct effects of job strain, perceived workplace support, perceived family support, and coping strategies on psychological distress and (2) the moderating effect of perceived workplace support, perceived family support, and coping strategies on the relationship between job strain and psychological distress. Lazarus and Folkman's transactional model of stress and coping guided this cross-sectional study. Full-time employed pregnant women (N = 300) were recruited from three antenatal clinics in Thailand. Thai versions of the following instruments were used: the State-Anxiety Inventory and Center for Epidemiological Studies-Depression Scale (psychological distress), the Job Content Questionnaire (job strain and perceived workplace support), the Medical Outcome Study Social Support Survey (perceived family support), and the Ways of Coping Checklist-Revised (coping strategies). Job strain with other predictors explained 54% of the variance in psychological distress. In the separate hierarchical multiple linear regression models, two types of coping strategies, seeking social support and wishful thinking, moderated the effects of job strain on psychological distress. Perceived family support had a direct effect in reducing psychological distress. Job strain is a significant contributor to psychological distress. The average levels of seeking social support and wishful thinking were most beneficial in moderating the negative impact of job strain on psychological distress. Since perceived workplace and family support did not have moderating effects, stress management programs for decreasing the levels of job strain should be developed.

  9. Wrinkling instability in nanoparticle-supported graphene: implications for strain engineering

    Science.gov (United States)

    Cullen, William; Yamamoto, Mahito; Pierre-Louis, Olivier; Huang, Jia; Fuhrer, Michael; Einstein, Theodore

    2013-03-01

    We have carried out a systematic study of the wrinkling instability of graphene membranes supported on SiO2 substrates with randomly placed silica nanoparticles. At small nanoparticle density, monolayer graphene adheres to the substrate and is highly conformal over the nanoparticles. With increasing nanoparticle density, and decreasing nanoparticle separation to ~100 nm, graphene's elastic response dominates substrate adhesion, and elastic stretching energy is reduced by the formation of wrinkles which connect protrusions. Above a critical nanoparticle density, the wrinkles form a percolating network through the sample. As the graphene membrane is made thicker, delamination from the substrate is observed. Since the wrinkling instability acts to remove inhomogeneous in-plane elastic strains through out-of-plane buckling, our results can be used to place limits on the possible in-plane strain magnitudes that may be created in graphene to realized strain-engineered electronic structures.[2] Supported by the UMD NSF-MRSEC under Grant No. DMR 05-20471, the US ONR MURI and UMD CNAM.

  10. Cloud Computing for the Grid: GridControl: A Software Platform to Support the Smart Grid

    Energy Technology Data Exchange (ETDEWEB)

    None

    2012-02-08

    GENI Project: Cornell University is creating a new software platform for grid operators called GridControl that will utilize cloud computing to more efficiently control the grid. In a cloud computing system, there are minimal hardware and software demands on users. The user can tap into a network of computers that is housed elsewhere (the cloud) and the network runs computer applications for the user. The user only needs interface software to access all of the cloud’s data resources, which can be as simple as a web browser. Cloud computing can reduce costs, facilitate innovation through sharing, empower users, and improve the overall reliability of a dispersed system. Cornell’s GridControl will focus on 4 elements: delivering the state of the grid to users quickly and reliably; building networked, scalable grid-control software; tailoring services to emerging smart grid uses; and simulating smart grid behavior under various conditions.

  11. Supporting relief efforts of the 2010 Haitian earthquake using an airborne multimodal remote sensing platform

    Science.gov (United States)

    Faulring, Jason W.; McKeown, Donald M.; van Aardt, Jan; Casterline, May V.; Bartlett, Brent D.; Raqueno, Nina

    2011-06-01

    The small island nation of Haiti was devastated in early 2010 following a massive 7.0 earthquake that brought about widespread destruction of infrastructure, many deaths and large-scale displacement of the population in the nation's major cities. The World Bank and ImageCat, Inc tasked the Rochester Institute of Technology's (RIT) Wildfire Airborne Sensor Platform (WASP) to gather a multi-spectral and multi-modal assessment of the disaster over a seven-day period to be used for relief and reconstruction efforts. Traditionally, private sector aerial remote sensing platforms work on processing and product delivery timelines measured in days, a scenario that has the potential to reduce the value of the data in time-sensitive situations such as those found in responding to a disaster. This paper will describe the methodologies and practices used by RIT to deliver an open set of products typically within a twenty-four hour period from when they were initially collected. Response to the Haiti disaster can be broken down into four major sections: 1) data collection and logistics, 2) transmission of raw data from a remote location to a central processing and dissemination location, 3) rapid image processing of a massive amount of raw data, and 4) dissemination of processed data to global organizations utilizing it to provide the maximum benefit. Each section required it's own major effort to ensure the success of the overall mission. A discussion of each section will be provided along with an analysis of methods that could be implemented in future exercises to increase efficiency and effectiveness.

  12. Efficient oxygen reduction reaction using ruthenium tetrakis(diaquaplatinum)octacarboxyphthalocyanine catalyst supported on MWCNT platform

    CSIR Research Space (South Africa)

    Maxakato, NW

    2011-02-01

    Full Text Available Electrocatalytic reduction of molecular oxygen in alkaline solution using a novel ruthenium tetrakis(diaquaplatinum) octacarboxyphthalocyanine (RuOCPcPt) electrocatalyst supported on multi-walled carbon nanotube electrode has been described. We show...

  13. VirtualPlant: A Software Platform to Support Systems Biology Research1[W][OA

    Science.gov (United States)

    Katari, Manpreet S.; Nowicki, Steve D.; Aceituno, Felipe F.; Nero, Damion; Kelfer, Jonathan; Thompson, Lee Parnell; Cabello, Juan M.; Davidson, Rebecca S.; Goldberg, Arthur P.; Shasha, Dennis E.; Coruzzi, Gloria M.; Gutiérrez, Rodrigo A.

    2010-01-01

    Data generation is no longer the limiting factor in advancing biological research. In addition, data integration, analysis, and interpretation have become key bottlenecks and challenges that biologists conducting genomic research face daily. To enable biologists to derive testable hypotheses from the increasing amount of genomic data, we have developed the VirtualPlant software platform. VirtualPlant enables scientists to visualize, integrate, and analyze genomic data from a systems biology perspective. VirtualPlant integrates genome-wide data concerning the known and predicted relationships among genes, proteins, and molecules, as well as genome-scale experimental measurements. VirtualPlant also provides visualization techniques that render multivariate information in visual formats that facilitate the extraction of biological concepts. Importantly, VirtualPlant helps biologists who are not trained in computer science to mine lists of genes, microarray experiments, and gene networks to address questions in plant biology, such as: What are the molecular mechanisms by which internal or external perturbations affect processes controlling growth and development? We illustrate the use of VirtualPlant with three case studies, ranging from querying a gene of interest to the identification of gene networks and regulatory hubs that control seed development. Whereas the VirtualPlant software was developed to mine Arabidopsis (Arabidopsis thaliana) genomic data, its data structures, algorithms, and visualization tools are designed in a species-independent way. VirtualPlant is freely available at www.virtualplant.org. PMID:20007449

  14. The Freshwater Information Platform - an online network supporting freshwater biodiversity research and policy

    Science.gov (United States)

    Schmidt-Kloiber, Astrid; De Wever, Aaike; Bremerich, Vanessa; Strackbein, Jörg; Hering, Daniel; Jähnig, Sonja; Kiesel, Jens; Martens, Koen; Tockner, Klement

    2017-04-01

    Species distribution data is crucial for improving our understanding of biodiversity and its threats. This is especially the case for freshwater environments, which are heavily affected by the global biodiversity crisis. Currently, a huge body of freshwater biodiversity data is often difficult to access, because systematic data publishing practices have not yet been adopted by the freshwater research community. The Freshwater Information Platform (FIP; www.freshwaterplatform.eu) - initiated through the BioFresh project - aims at pooling freshwater related research information from a variety of projects and initiatives to make it easily accessible for scientists, water managers and conservationists as well as the interested public. It consists of several major components, three of which we want to specifically address: (1) The Freshwater Biodiversity Data Portal aims at mobilising freshwater biodiversity data, making them online available Datasets in the portal are described and documented in the (2) Freshwater Metadatabase and published as open access articles in the Freshwater Metadata Journal. The use of collected datasets for large-scale analyses and models is demonstrated in the (3) Global Freshwater Biodiversity Atlas that publishes interactive online maps featuring research results on freshwater biodiversity, resources, threats and conservation priorities. Here we present the main components of the FIP as tools to streamline open access freshwater data publication arguing this will improve the capacity to protect and manage freshwater biodiversity in the face of global change.

  15. Suppressed superconductivity in substrate-supported β 12 borophene by tensile strain and electron doping

    Science.gov (United States)

    Cheng, Cai; Sun, Jia-Tao; Liu, Hang; Fu, Hui-Xia; Zhang, Jin; Chen, Xiang-Rong; Meng, Sheng

    2017-06-01

    Planar borophene, the truly 2D monolayer boron, has been independently successfully grown on Ag(1 1 1) by two groups (2016 Nat. Chem. 8 563 and 2015 Science 350 1513), which has received widespreading attentions. The superconducting property has not been unambiguously observed, which is unexpected because light element boron should have strong electron-phonon coupling. To resolve this puzzle, we show that the superconducting transition temperature T c of β 12 borophene is effectively suppressed by the substrate-induced tensile strain and electron doping via first principles calculations. The biaxial tensile strain of 2% induced by Ag(1 1 1) significantly reduces T c from 14 K to 2.95 K electron doping of 0.1 e- per boron atom further shrinks T c to 0.09 K. We also predict that the superconducting transition temperature in β 12 can be enhanced to 22.82 K with proper compressive strain (-1%) and 18.97 K with hole doping (0.1 h+ per boron). Further studies indicate that the variation of T c is closely related to the density of states of σ bands near the Fermi surface. Our results help to explain the challenges to experimentally probe superconductivity in substrate-supported borophene.

  16. The relationships between psychological strain, organizational support, affective commitment and turnover intentions of highly educated hospitality employees

    NARCIS (Netherlands)

    Tromp, D.M.; Rheede, van A.; Blomme, R.J.

    2010-01-01

    Turnover of highly educated employees in the hospitality industry is growing rapidly. A predictor of turnover in the hospitality industry recently put forward, but not yet fully researched, is psychological strain. This chapter investigates the role of psychological strain and organizational support

  17. SemanticSCo: a platform to support the semantic composition of services for gene expression analysis

    NARCIS (Netherlands)

    Guardia, Gabriela D.A.; Ferreira Pires, Luis; Goncalves da Silva, Eduardo; Guareis de farias, Cléver

    Gene expression studies often require the combined use of a number of analysis tools. However, manual integration of analysis tools can be cumbersome and error prone. To support a higher level of automation in the integration process, efforts have been made in the biomedical domain towards the

  18. Developing a Web Server Platform with SAPI support for AJAX RPC using JSON

    Directory of Open Access Journals (Sweden)

    2007-01-01

    Full Text Available Writing a custom web server with SAPI support is a useful task which helps students and future system architects to understand the link between network programming, object oriented programming, enterprise application designing patterns and development best practices because it offers a vision upon interprocess communication and application extensibility in a distributed environment

  19. Construction of a prophage-free variant of Corynebacterium glutamicum ATCC 13032 for use as a platform strain for basic research and industrial biotechnology.

    Science.gov (United States)

    Baumgart, Meike; Unthan, Simon; Rückert, Christian; Sivalingam, Jasintha; Grünberger, Alexander; Kalinowski, Jörn; Bott, Michael; Noack, Stephan; Frunzke, Julia

    2013-10-01

    The activity of bacteriophages and phage-related mobile elements is a major source for genome rearrangements and genetic instability of their bacterial hosts. The genome of the industrial amino acid producer Corynebacterium glutamicum ATCC 13032 contains three prophages (CGP1, CGP2, and CGP3) of so far unknown functionality. Several phage genes are regularly expressed, and the large prophage CGP3 (∼190 kbp) has recently been shown to be induced under certain stress conditions. Here, we present the construction of MB001, a prophage-free variant of C. glutamicum ATCC 13032 with a 6% reduced genome. This strain does not show any unfavorable properties during extensive phenotypic characterization under various standard and stress conditions. As expected, we observed improved growth and fitness of MB001 under SOS-response-inducing conditions that trigger CGP3 induction in the wild-type strain. Further studies revealed that MB001 has a significantly increased transformation efficiency and produced about 30% more of the heterologous model protein enhanced yellow fluorescent protein (eYFP), presumably as a consequence of an increased plasmid copy number. These effects were attributed to the loss of the restriction-modification system (cg1996-cg1998) located within CGP3. The deletion of the prophages without any negative effect results in a novel platform strain for metabolic engineering and represents a useful step toward the construction of a C. glutamicum chassis genome of strain ATCC 13032 for biotechnological applications and synthetic biology.

  20. Mobil4D platform: A mobile learning opportunity and support for nursing education

    CSIR Research Space (South Africa)

    Ogunleye, OS

    2010-10-01

    Full Text Available : Mobi4D, Mobile Learning, Nursing Education, a few, keywords, here. 1. Introduction The use of computers in education has been focused on supporting learning in formal settings, such as the classroom or computer laboratory. However, one... a physical environment both outdoor (e.g. Hospital and home) and indoor (e.g. classroom) (Rogers et al, 2005). Current Mobile Technology, particularly, wireless frequently referred to as third generation (3G) provide an unprecedented opportunity...

  1. Video Conferencing Services in Healthcare: One Communication Platform to Support All.

    Science.gov (United States)

    Budrionis, Andrius; Hasvold, Per; Hartvigsen, Gunnar; Bellika, Johan Gustav

    2015-01-01

    We present a novel approach to the design of video conferencing (VC) systems, taking advantage of recent technological achievements in web-based implementation. Delivering VC functionality as a service over the Internet opens new grounds for easier integration, support, and application in many scenarios, since hardware-agnostic ad-hoc VC connections are a feature of the proposed architecture. Validity is demonstrated through latency measures in surgical telementoring service and comparing them to reported thresholds.

  2. Design of multilevel flow modelling-based decision support system by using multiagent platform

    DEFF Research Database (Denmark)

    Zhang, Xinxin; Lind, Morten; Ravn, Ole

    2015-01-01

    For complex engineering systems, there is an increasing demand forsafety and reliability. Decision support system (DSS) is designed to offersupervision and analysis about operational situations. A proper modelrepresentation is required for DSS to understand the process knowledge.Multilevel flow m...... available techniques of MFM reasoning and less matureyet relevant MFM concepts are considered. It also offers an architecture designof task organisation for MFM software tools by using the concept of agent andtechnology of multiagent software system......For complex engineering systems, there is an increasing demand forsafety and reliability. Decision support system (DSS) is designed to offersupervision and analysis about operational situations. A proper modelrepresentation is required for DSS to understand the process knowledge.Multilevel flow...... modelling (MFM) represents complex system in multiplelevels of means-end and part-whole decompositions, which is proposed in thispaper as basis for developing decision support systems. The aim of this paper isto explore the different possible functionalities by applying MFM to DSS,where both currently...

  3. A decision support system for telemedicine through the mobile telecommunications platform.

    Science.gov (United States)

    Eren, Ali; Subasi, Abdulhamit; Coskun, Osman

    2008-02-01

    In this paper we have discussed the application of artificial intelligence in telemedicine using mobile device. The main goal of our research is to develop methods and systems to collect, analyze, distribute and use medical diagnostics information from multiple knowledge sources and areas of expertise. Physicians may collect and analyze information obtained from experts worldwide with the help of a medical decision support system. In this information retrieval system, modern communication tools such as computers and mobile phones can be used efficiently. In this work we propose a medical decision support system using the general packet radio service (GPRS). GPRS, a data extension of the mobile telephony standard Global system for mobile communications (GSM) is emerging as the first true packet-switched architecture to allow mobile subscribers to benefit from high-speed transmission rates and run JAVA based applications from their mobile terminals. An academic prototype of a medical decision support system using mobile device was implemented. The results reveal that the system could find acceptance from the medical community and it could be an effective means of providing quality health care in developing countries.

  4. Temporal patterns of rat behaviour in the central platform of the elevated plus maze. Comparative analysis between male subjects of strains with different basal levels of emotionality.

    Science.gov (United States)

    Casarrubea, M; Faulisi, F; Caternicchia, F; Santangelo, A; Di Giovanni, G; Benigno, A; Magnusson, M S; Crescimanno, G

    2016-08-01

    We have analyzed the temporal patterns of behaviour of male rats of the Wistar and DA/Han strains on the central platform of the elevated plus maze. The ethogram encompassed 10 behavioural elements. Durations, frequencies and latencies showed quantitative differences as to walking and sniffing activities. Wistar rats displayed significantly lower latency and significantly higher durations and frequencies of walking activities. DA/Han rats showed a significant increase of sniffing duration. In addition, DA/Han rats showed a significantly higher amount of time spent in the central platform. Multivariate T-pattern analysis revealed differences in the temporal organization of behaviour of the two rat strains. DA/Han rats showed (a) higher behavioural complexity and variability and (b) a significantly higher mean number of T-patterns than Wistar rats. Taken together, T-pattern analysis of behaviour in the centre of the elevated plus maze can noticeably improve the detection of subtle features of anxiety related behaviour. We suggest that T-pattern analysis could be used as sensitive tool to test the action of anxiolytic and anxiogenic manipulations.

  5. Investigation of Doppler Effects on high mobility OFDM-MIMO systems with the support of High Altitude Platforms (HAPs)

    Science.gov (United States)

    Mohammed, H. A.; Sibley, M. J. N.; Mather, P. J.

    2012-05-01

    The merging of Orthogonal Frequency Division Multiplexing (OFDM) with Multiple-input multiple-output (MIMO) is a promising mobile air interface solution for next generation wireless local area networks (WLANs) and 4G mobile cellular wireless systems. This paper details the design of a highly robust and efficient OFDM-MIMO system to support permanent accessibility and higher data rates to users moving at high speeds, such as users travelling on trains. It has high relevance for next generation wireless local area networks (WLANs) and 4G mobile cellular wireless systems. The paper begins with a comprehensive literature review focused on both technologies. This is followed by the modelling of the OFDM-MIMO physical layer based on Simulink/Matlab that takes into consideration high vehicular mobility. Then the entire system is simulated and analysed under different encoding and channel estimation algorithms. The use of High Altitude Platform system (HAPs) technology is considered and analysed.

  6. Development and case study of a science-based software platform to support policy making on air quality

    Institute of Scientific and Technical Information of China (English)

    Yun Zhu; Yahweh Lao; Carey Jang; Chen-Jen Lin; Jia Xing; Shuxiao Wang; Joshua S.Fu

    2015-01-01

    This article describes the development and implementations of a novel software platform that supports real-time,science-based policy making on air quality through a user-friendly interface.The software,RSM-VAT,uses a response surface modeling (RSM) methodology and serves as a visualization and analysis tool (VAT) for three-dimensional air quality data obtained by atmospheric models.The software features a number of powerful and intuitive data visualization functions for illustrating the complex nonlinear relationship between emission reductions and air quality benefits.The case study of contiguous U.S.demonstrates that the enhanced RSM-VAT is capable of reproducing the air quality model results with Normalized Mean Bias <2% and assisting in air quality policy making in near real time.

  7. Evaluating acceptance and user experience of a guideline-based clinical decision support system execution platform.

    Science.gov (United States)

    Buenestado, David; Elorz, Javier; Pérez-Yarza, Eduardo G; Iruetaguena, Ander; Segundo, Unai; Barrena, Raúl; Pikatza, Juan M

    2013-04-01

    This study aims to determine what the initial disposition of physicians towards the use of Clinical Decision Support Systems (CDSS) based on Computerised Clinical Guidelines and Protocols (CCGP) is; and whether their prolonged utilisation has a positive effect on their intention to adopt them in the future. For a period of 3 months, 8 volunteer paediatricians monitored each up to 10 asthmatic patients using two CCGPs deployed in the-GuidesMed CDSS. A Technology Acceptance Model (TAM) questionnaire was supplied to them before and after using the system. Results from both questionnaires are analysed searching for significant improvements in opinion between them. An additional survey was performed to analyse the usability of the system. It was found that initial disposition of physicians towards e-GuidesMed is good. Improvement between the pre and post iterations of the TAM questionnaire has been found to be statistically significant. Nonetheless, slightly lower values in the Compatibility and Habit variables show that participants perceive possible difficulties to integrate e-GuidesMed into their daily routine. The variable Facilitators shows the highest correlation with the Intention to Use. Usability of the system has also been rated very high and, in this regard, no fundamental flaw has been detected. Initial views towards e-GuidesMed are positive, and become reinforced after continued utilisation of the system. In order to achieve an effective implementation, it becomes essential to facilitate conditions to integrate the system into the physician's daily routine.

  8. PopHR: a knowledge-based platform to support integration, analysis, and visualization of population health data.

    Science.gov (United States)

    Shaban-Nejad, Arash; Lavigne, Maxime; Okhmatovskaia, Anya; Buckeridge, David L

    2017-01-01

    Population health decision makers must consider complex relationships between multiple concepts measured with differential accuracy from heterogeneous data sources. Population health information systems are currently limited in their ability to integrate data and present a coherent portrait of population health. Consequentially, these systems can provide only basic support for decision makers. The Population Health Record (PopHR) is a semantic web application that automates the integration and extraction of massive amounts of heterogeneous data from multiple distributed sources (e.g., administrative data, clinical records, and survey responses) to support the measurement and monitoring of population health and health system performance for a defined population. The design of the PopHR draws on the theories of the determinants of health and evidence-based public health to harmonize and explicitly link information about a population with evidence about the epidemiology and control of chronic diseases. Organizing information in this manner and linking it explicitly to evidence is expected to improve decision making related to the planning, implementation, and evaluation of population health and health system interventions. In this paper, we describe the PopHR platform and discuss the architecture, design, key modules, and its implementation and use. © 2016 New York Academy of Sciences.

  9. Job Strain and Self-Reported Insomnia Symptoms among Nurses: What about the Influence of Emotional Demands and Social Support?

    Science.gov (United States)

    Portela, Luciana Fernandes; Kröning Luna, Caroline; Rotenberg, Lúcia; Silva-Costa, Aline; Toivanen, Susanna; Araújo, Tania; Griep, Rosane Härter

    2015-01-01

    Job strain, derived from high psychological demands and low job control, is associated with insomnia, but information on the role of emotional demands and social support in this relationship is scarce. The aims of this study were (i) to test the association between job strain and self-reported insomnia symptoms, (ii) to evaluate the combination of emotional demands and job control regarding insomnia symptoms, and (iii) to analyze the influence of social support in these relationships. This cross-sectional study refers to a sample of nurses (N = 3,013 and N = 3,035 for Job Strain and Emotional demand-control model, resp.) working at public hospitals in Rio de Janeiro, Brazil. Data were collected through a self-report questionnaire. The prevalence of insomnia symptoms was 34.3%. Job strain was associated with increased odds for insomnia symptoms (OR: 2.20); the same result was observed with the combination of emotional demands and low job control (OR: 1.99). In both models, the inclusion of low social support combined with high demands and low job control led to increased odds for insomnia symptoms, compared to groups with high social support from coworkers and supervisors. Besides job strain, the study of emotional demands and social support are promising with regards to insomnia symptoms, particularly among nurses.

  10. Job Strain and Self-Reported Insomnia Symptoms among Nurses: What about the Influence of Emotional Demands and Social Support?

    Directory of Open Access Journals (Sweden)

    Luciana Fernandes Portela

    2015-01-01

    Full Text Available Job strain, derived from high psychological demands and low job control, is associated with insomnia, but information on the role of emotional demands and social support in this relationship is scarce. The aims of this study were (i to test the association between job strain and self-reported insomnia symptoms, (ii to evaluate the combination of emotional demands and job control regarding insomnia symptoms, and (iii to analyze the influence of social support in these relationships. This cross-sectional study refers to a sample of nurses (N = 3,013 and N = 3,035 for Job Strain and Emotional demand-control model, resp. working at public hospitals in Rio de Janeiro, Brazil. Data were collected through a self-report questionnaire. The prevalence of insomnia symptoms was 34.3%. Job strain was associated with increased odds for insomnia symptoms (OR: 2.20; the same result was observed with the combination of emotional demands and low job control (OR: 1.99. In both models, the inclusion of low social support combined with high demands and low job control led to increased odds for insomnia symptoms, compared to groups with high social support from coworkers and supervisors. Besides job strain, the study of emotional demands and social support are promising with regards to insomnia symptoms, particularly among nurses.

  11. Supported Lipid Bilayer Platform To Test Inhibitors of the Membrane Attack Complex: Insights into Biomacromolecular Assembly and Regulation.

    Science.gov (United States)

    Yorulmaz, Saziye; Jackman, Joshua A; Hunziker, Walter; Cho, Nam-Joon

    2015-11-01

    Complement activation plays an important role in innate immune defense by triggering formation of the membrane attack complex (MAC), which is a biomacromolecular assembly that exhibits membrane-lytic activity against foreign invaders including various pathogens and biomaterials. Understanding the details of MAC structure and function has been the subject of extensive work involving bulk liposome and erythrocyte assays. However, it is difficult to characterize the mechanism of action of MAC inhibitor drug candidates using the conventional assays. To address this issue, we employ a biomimetic supported lipid bilayer platform to investigate how two MAC inhibitors, vitronectin and clusterin, interfere with MAC assembly in a sequential addition format, as monitored by the quartz crystal microbalance-dissipation (QCM-D) technique. Two experimental strategies based on modular assembly were selected, precincubation of inhibitor and C5b-7 complex before addition to the lipid bilayer or initial addition of inhibitor followed by the C5b-7 complex. The findings indicate that vitronectin inhibits membrane association of C5b-7 via a direct interaction with C5b-7 and via competitive membrane association onto the supported lipid bilayer. On the other hand, clusterin directly interacts with C5b-7 such that C5b-7 is still able to bind to the lipid bilayer, and clusterin affects the subsequent binding of other complement proteins involved in the MAC assembly. Taken together, the findings in this study outline a biomimetic approach based on supported lipid bilayers to explore the interactions between complement proteins and inhibitors, thereby offering insight into MAC assembly and regulation.

  12. Biofilm as a production platform for heterologous production of rhamnolipids by the non‑pathogenic strain Pseudomonas putida KT2440

    DEFF Research Database (Denmark)

    Wigneswaran, Vinoth; Nielsen, Kristian Fog; Sternberg, Claus

    2016-01-01

    C10 fatty acids. Conclusion This study shows a successful application of synthetic promoter library in P. putida KT2440 and a heterologous biosynthesis of rhamnolipids in biofilm encased cells without hampering biofilm capabilities. These findings expands the possibilities of cultivation setups......Background Although a transition toward sustainable production of chemicals is needed, the physiochemical properties of certain biochemicals such as biosurfactants make them challenging to produce in conventional bioreactor systems. Alternative production platforms such as surface-attached biofilm...... as the model compound in biofilm encased Pseudomonas putida KT2440. The rhlAB operon from P. aeruginosa was introduced into P. putida to produce mono-rhamnolipids. A synthetic promoter library was used in order to bypass the normal regulation of rhamnolipid synthesis and to provide varying expression levels...

  13. [The Moodle platform: A useful tool for training in life support. Analysis of satisfaction questionnaires from students and instructors of the semFYC advanced life support courses].

    Science.gov (United States)

    Cordero Torres, Juan Antonio; Caballero Oliver, Antonio

    2015-01-01

    The aim of this study is to assess the validity and use of a mixed method of training in life support. The use of Moodle to implement an online pre-sessional phase prior to a "classic" classroom phase of teaching in this type of course is the main novelty. Analysis of satisfaction questionnaires of students and instructors of a mixed course in the advanced life support program of SemFYC (ESVAP). Moodle platform. semFYC Virtual Classroom. Students and instructors participating in the semFYC advanced life support program, ESVAP. Qualitative analysis. The majority of students rate as very useful (50%) or useful (45.37%) the existence of an online pre-sessional phase, and consider that it has helped them very much (42.20%) or quite a lot (48.62%) to make the most of the face-to-face sessions. For instructors, they considered that the existence of an online pre-sessional phase was very useful (89%) or useful (11%) for the development of the face-to-face sessions. The analysis of the results concluded that: 1) the students considered a prior non-face to face phase as very useful, and it helped them much/very much in the face to face phase, and 2) the instructors believe that the non-face to face phase had helped them a lot in the presentations and efficiency of the workshops in the face-to-face phase. Copyright © 2014 Elsevier España, S.L.U. All rights reserved.

  14. Maximum Stress Estimation Model for Multi-Span Waler Beams with Deflections at the Supports Using Average Strains

    Directory of Open Access Journals (Sweden)

    Sung Woo Park

    2015-03-01

    Full Text Available The safety of a multi-span waler beam subjected simultaneously to a distributed load and deflections at its supports can be secured by limiting the maximum stress of the beam to a specific value to prevent the beam from reaching a limit state for failure or collapse. Despite the fact that the vast majority of accidents on construction sites occur at waler beams in retaining wall systems, no safety monitoring model that can consider deflections at the supports of the beam is available. In this paper, a maximum stress estimation model for a waler beam based on average strains measured from vibrating wire strain gauges (VWSGs, the most frequently used sensors in construction field, is presented. The model is derived by defining the relationship between the maximum stress and the average strains measured from VWSGs. In addition to the maximum stress, support reactions, deflections at supports, and the magnitudes of distributed loads for the beam structure can be identified by the estimation model using the average strains. Using simulation tests on two multi-span beams, the performance of the model is evaluated by estimating maximum stress, deflections at supports, support reactions, and the magnitudes of distributed loads.

  15. MOSES Support Platform

    Science.gov (United States)

    2008-02-01

    be moved for stowage , or readied for re-deployment. MSP Design Low cost was an objective of the MSP design. The design used COTS equipment...operated by a rack and pinion mechanism on each leg. The same diesel generator that powers the auxiliary equipment supplies the power for the jack

  16. Principles and Best Practices Emerging from Data Basin: A Data Platform Supporting Scientific Research and Landscape Conservation Planning

    Science.gov (United States)

    Comendant, T.; Strittholt, J. R.; Ward, B. C.; Bachelet, D. M.; Grossman, D.; Stevenson-Molnar, N.; Henifin, K.; Lundin, M.; Marvin, T. S.; Peterman, W. L.; Corrigan, G. N.; O'Connor, K.

    2013-12-01

    A multi-disciplinary team of scientists, software engineers, and outreach staff at the Conservation Biology Institute launched an open-access, web-based spatial data platform called Data Basin (www.databasin.org) in 2010. Primarily built to support research and environmental resource planning, Data Basin provides the capability for individuals and organizations to explore, create, interpret, and collaborate around their priority topics and geographies. We used a stakeholder analysis to assess the needs of data consumers/produces and help prioritize primary and secondary audiences. Data Basin's simple and user-friendly interface makes mapping and geo-processing tools more accessible to less technical audiences. Input from users is considered in system planning, testing, and implementation. The team continually develops using an agile software development approach, which allows new features, improvements, and bug fixes to be deployed to the live system on a frequent basis. The data import process is handled through administrative approval and Data Basin requires spatial data (biological, physical, and socio-economic) to be well-documented. Outreach and training is used to convey the scope and appropriate use of the scientific information and available resources.

  17. Using the Moodle platform as a support for face-to-face classes: an experience Report from Master degree classes

    Directory of Open Access Journals (Sweden)

    Eniel Espirito Santo

    2013-11-01

    Full Text Available This paper discusses the inclusion and use of ICTs in higher education at a postgraduate level; specifically in Master courses.  It presents some possibilities and opportunities for the use of technology in teaching mediation, including them as indispensable tools in the teaching and learning process. This is an exploratory and descriptive research that uses - as a source - both the review of the literature and a field research paper that is developed in an experience report format. The field research paper presents the experience of classes delivered in Master courses using Moodle as a complementary support platform to the lectures at two universities located in South America. Taking into account a methodological triangulation, collection techniques for the focus groups, questionnaires and participant observations were used as data. The paper concludes that the actual classes in the postgraduate courses may be made more dynamic with the use of technological tools that enable interaction before, during and after classroom activities, encouraging a pleasant and meaningful learning.

  18. Treatment Outcome of Two Adjacent Implant-Supported Restorations with Different Implant Platform Designs in the Esthetic Region : A Five-Year Randomized Clinical Trial

    NARCIS (Netherlands)

    Van Nimwegen, Wouter G.; Raghoebar, Gerry M.; Stellingsma, Kees; Tymstra, Nynke; Vissink, Arjan; Meijer, Henny J. A.

    2015-01-01

    Purpose: The aim of this study was to evaluate the peri-implant soft and hard tissues and satisfaction in patients with two adjacent implant-supported restorations in the esthetic region, treated with two adjacent implants with a scalloped or flat platform. Materials and Methods: The randomized clin

  19. Product Platform Performance

    DEFF Research Database (Denmark)

    Munk, Lone

    engaging in platform-based product development. Similarly platform assessment criteria lack empirical verification regarding relevance and sufficiency. The thesis focuses on • the process of identifying and estimating internal effects, • verification of performance of product platforms, (i...... to support this understanding. Finally a categorisation of different approaches to platform-based product development is introduced, based on the companies from the industrial study.......The aim of this research is to improve understanding of platform-based product development by studying platform performance in relation to internal effects in companies. Platform-based product development makes it possible to deliver product variety and at the same time reduce the needed resources...

  20. Engineering of a Nepetalactol-Producing Platform Strain of Saccharomyces cerevisiae for the Production of Plant Seco-Iridoids.

    Science.gov (United States)

    Campbell, Alex; Bauchart, Philippe; Gold, Nicholas D; Zhu, Yun; De Luca, Vincenzo; Martin, Vincent J J

    2016-05-20

    The monoterpene indole alkaloids (MIAs) are a valuable family of chemicals that include the anticancer drugs vinblastine and vincristine. These compounds are of global significance-appearing on the World Health Organization's list of model essential medicines-but remain exorbitantly priced due to low in planta levels. Chemical synthesis and genetic manipulation of MIA producing plants such as Catharanthus roseus have so far failed to find a solution to this problem. Synthetic biology holds a potential answer, by building the pathway into more tractable organisms such as Saccharomyces cerevisiae. Recent work has taken the first steps in this direction by producing small amounts of the intermediate strictosidine in yeast. In order to help improve on these titers, we aimed to optimize the early biosynthetic steps of the MIA pathway to the metabolite nepetalactol. We combined a number of strategies to create a base strain producing 11.4 mg/L of the precursor geraniol. We also show production of the critical intermediate 10-hydroxygeraniol and demonstrate nepetalactol production in vitro. Lastly we demonstrate that activity of the iridoid synthase toward the intermediates geraniol and 10-hydroxygeraniol results in the synthesis of the nonproductive intermediates citronellol and 10-hydroxycitronellol. This discovery has serious implications for the reconstruction of the MIA in heterologous organisms.

  1. Assessing the Quality, Feasibility, and Efficacy of Electronic Patient Platforms Designed to Support Adolescents and Young Adults With Cancer: A Systematic Review Protocol

    Science.gov (United States)

    McCann, Lisa

    2017-01-01

    Background A range of innovative websites, mobile technologies, eHealth and mHealth platforms have emerged to support adolescents and young adults (AYAs) with cancer. Previous reviews have identified these various applications and solutions, but no review has summarized the quality, feasibility, and efficacy of existing patient platforms (inclusive of websites, mobile technologies, mHealth and eHealth platforms) developed specifically for young people with cancer. Objective This paper describes the design of a protocol to conduct a review of published studies or reports which describe or report on an existing platform designed specifically for AYAs who have had a cancer diagnosis. Methods A search string was developed using a variety of key words and Medical Subject Heading and applied to bibliographic databases. General data (sample characteristics, patient platform development, design and, if applicable, pilot testing outcomes) will be extracted from reports and studies. Drawing on a previously developed coding schematic, the identified patient platforms will be coded for mode of delivery into (1) automated functions, (2) communicative functions, and (3) use of supplementary modes. An adapted version of the Mobile App Rating Scale (MARS) will be used to assess the of quality of each identified patient platform. The methodological quality of included studies will be assessed using the Quality Assessment Criteria for Evaluating Primary Research Papers from a Variety of Fields (QualSyst). Both authors will independently screen eligible studies for final inclusion and will both be responsible for data extraction and appraisal. Data will be synthesized narratively to provide an overview of identified patient platforms. Results The review began in October 2016 and is currently in progress. The review paper will be submitted for peer-review and publication in the summer of 2017. Conclusions This review will be unique in its focus on assessing, where possible, the

  2. Assessing the Quality, Feasibility, and Efficacy of Electronic Patient Platforms Designed to Support Adolescents and Young Adults With Cancer: A Systematic Review Protocol.

    Science.gov (United States)

    Pugh, Gemma; McCann, Lisa

    2017-01-17

    A range of innovative websites, mobile technologies, eHealth and mHealth platforms have emerged to support adolescents and young adults (AYAs) with cancer. Previous reviews have identified these various applications and solutions, but no review has summarized the quality, feasibility, and efficacy of existing patient platforms (inclusive of websites, mobile technologies, mHealth and eHealth platforms) developed specifically for young people with cancer. This paper describes the design of a protocol to conduct a review of published studies or reports which describe or report on an existing platform designed specifically for AYAs who have had a cancer diagnosis. A search string was developed using a variety of key words and Medical Subject Heading and applied to bibliographic databases. General data (sample characteristics, patient platform development, design and, if applicable, pilot testing outcomes) will be extracted from reports and studies. Drawing on a previously developed coding schematic, the identified patient platforms will be coded for mode of delivery into (1) automated functions, (2) communicative functions, and (3) use of supplementary modes. An adapted version of the Mobile App Rating Scale (MARS) will be used to assess the of quality of each identified patient platform. The methodological quality of included studies will be assessed using the Quality Assessment Criteria for Evaluating Primary Research Papers from a Variety of Fields (QualSyst). Both authors will independently screen eligible studies for final inclusion and will both be responsible for data extraction and appraisal. Data will be synthesized narratively to provide an overview of identified patient platforms. The review began in October 2016 and is currently in progress. The review paper will be submitted for peer-review and publication in the summer of 2017. This review will be unique in its focus on assessing, where possible, the quality and efficacy of patient platforms for

  3. An end-to-end microfluidic platform for engineering life supporting microbes in space exploration missions Project

    Data.gov (United States)

    National Aeronautics and Space Administration — HJ Science & Technology proposes a programmable, low-cost, and compact microfluidic platform capable of running automated end-to-end processes and optimization...

  4. Developing Knowledge-Based Citizen Participation Platform to Support Smart City Decision Making: The Smarticipate Case Study

    National Research Council Canada - National Science Library

    Zaheer Khan; Jens Dambruch; Jan Peters-Anders; Andreas Sackl; Anton Strasser; Peter Fröhlich; Simon Templer; Kamran Soomro

    2017-01-01

    .... Using such a system as a communication platform between citizens and city administrations provides an integrated top-down and bottom-up urban planning and decision-making approach to smart cities...

  5. On the Supply Chain Management Supported by E-Commerce Service Platform for Agreement based Circulation of Fruits and Vegetables

    Science.gov (United States)

    Bao, Liwei; Huang, Yuchi; Ma, Zengjun; Zhang, Jie; Lv, Qingchu

    According to analysis of the supply chain process of agricultural products, the IT application requirements of the market entities participating in the agreement based circulation of fruits and vegetables have been discussed. The strategy of supply chain management basing on E-commerce service platform for fruits and vegetables has been proposed in this paper. The architecture and function composing of the service platform have been designed and implemented. The platform is constructed on a set of application service modules User can choose some of the application service modules and define them according to the business process. The application service modules chosen and defined by user are integrated as an application service package and applied as management information system of business process. With the E-commerce service platform, the supply chain management for agreement based circulation of agricultural products of vegetables and fruits can be implemented.

  6. Cyber-infrastructure for Fusarium (CiF): Three integrated platforms supporting strain identification, phylogenetics, comparative genomics, and knowledge sharing

    Science.gov (United States)

    The fungal genus Fusarium includes many plant and/or animal pathogenic species and produces diverse toxins. Although accurate identification is critical for managing such threats, it is difficult to identify Fusarium morphologically. Fortunately, extensive molecular phylogenetic studies, founded on ...

  7. Ocean Data Interoperability Platform (ODIP): supporting the development of a common global framework for marine data management through international collaboration

    Science.gov (United States)

    Glaves, Helen; Schaap, Dick; Arko, Robert; Proctor, Roger

    2014-05-01

    Ecosystem level marine research necessitates that large amounts of interoperable data are readily available for use in a wide range of new and complex multidisciplinary applications. Significant amounts of marine data and information are available throughout the world due to the implementation of e-infrastructures at a regional level to manage and deliver this data to the end user. However, each of these initiatives has been developed to address specific regional requirements and independently of those in other regions. To establish a common framework for marine data management on a global scale that supports an ecosystem level approach to marine research there is a need to develop interoperability across these existing data infrastructures. The Ocean Data Interoperability (ODIP) project is creating a co-ordination platform to support collaboration between a number of these existing regional e-infrastructures which include Rolling Deck to Repository (R2R) in the USA, SeaDataNet and Geo-Seas in Europe, IMOS in Australia and also the international IODE initiative. To demonstrate this co-ordinated approach several prototypes will be developed to test and evaluate potential interoperability solutions for solving the incompatibilities identified between the different regional data infrastructures. These prototypes will be used to underpin the development of a common approach to the management of marine data which can also be promoted to the wider marine research community with a view to expanding this framework to include other regional marine data infrastructures. To achieve these objectives relevant domain experts are coming together at a series of workshops where areas of commonality between the regional infrastructures will be identified which can then be used as the foundation for the development of the prototype solutions. As a result six topics are currently being addressed by the ODIP project which have been identified and analysed during the first two ODIP

  8. Research on Network Service & Supporting Platform in Internet of Things%物联网网络服务支撑平台方案研究

    Institute of Scientific and Technical Information of China (English)

    赵俊钰; 诸旻; 左建; 黄剑琪

    2011-01-01

    This paper introduces the Internet of things architecture and emphasizes the necessity and urgency for domestic operators to construct network service & supporting platform in Internet of things with the expierences of foreign operators. Then it provides a specific plan of network service & supporting platform in Internet of things and describes the platform location and architecture in detail. Finally, it suggests some deployment strategy of the platform.%从物联网的体系架构出发,结合物联网业务的发展现状及国外运营商的经验,强调国内运营商建设物联网网络支撑平台的必要性和紧迫性,进而提出一种物联网网络服务支撑平台的建设方案,并对平台定位和架构进行了详细介绍,最后给出平台的一些部署策略.

  9. Mutant strains of Spirulina (Arthrospira) platensis to increase the efficiency of micro-ecological life support systems

    Science.gov (United States)

    Brown, Igor

    The European Micro-Ecological Life Support System Alternative (MELiSSA) is an advanced idea for organizing a bioregenerative system for long term space flights and extraterrestrial settlements (Hendrickx, De Wever et al., 2005). Despite the hostility of both lunar and Martian environments to unprotected life, it seems possible to cultivate photosynthetic bacteria using closed bioreactors illuminated and heated by solar energy. Such reactors might be employed in critical processes, e.g. air revitalization, foodcaloric and protein source, as well as an immunomodulators production. The MELiSSA team suggested cyanobacterium Spirulina as most appropriate agent to revitalize air and produce a simple "fast" food. This is right suggestion because Spirulina was recently shown to be an oxygenic organism with the highest level of O2 production per unit mass (Ananyev et al., 2005). Chemical composition of Spirulina includes proteins (55Aiming to make Spirulina cultivation in life support systems like MELiSSA more efficient, we selected Spirulina mutant strains with increased fraction of methionine in the biomass of this cyanobacterium and compared the effect of parental wild strain of Spirulina and its mutants on the tendency of such experimental illnesses as radiationinduced lesions and hemolythic anemia. Results: It was found that mutant strains 198B and 27G contain higher quantities of total protein, essential amino acids, c-phycocyanin, allophycocyanin and chlorophyll a than parental wild strain of S. platensis. The strain 198B is also characterized with increased content of carotenoids. Revealed biochemical peculiarities of mutant strains suggest that these strains can serve as an additional source of essential amino acids as well as phycobiliproteins and carotenoids for the astronauts. Feeding animals suffering from radiation-induced lesions, c-phycocyanin, extracted from strain 27G, led to a correction in deficient dehydrogenase activity and energy-rich phosphate levels

  10. Rolling Deck to Repository (R2R): Supporting Global Data Access Through the Ocean Data Interoperability Platform (ODIP)

    Science.gov (United States)

    Arko, R. A.; Stocks, K.; Chandler, C. L.; Smith, S. R.; Miller, S. P.; Maffei, A. R.; Glaves, H. M.; Carbotte, S. M.

    2013-12-01

    The U.S. National Science Foundation supports a fleet of academic research vessels operating throughout the world's oceans. In addition to supporting the mission-specific goals of each expedition, these vessels routinely deploy a suite of underway environmental sensors, operating like mobile observatories. Recognizing that the data from these instruments have value beyond each cruise, NSF funded R2R in 2009 to ensure that these data are routinely captured, cataloged and described, and submitted to the appropriate national repository for long-term public access. In 2013, R2R joined the Ocean Data Interoperability Platform (ODIP; http://odip.org/). The goal of ODIP is to remove barriers to the effective sharing of data across scientific domains and international boundaries, by providing a forum to harmonize diverse regional systems. To advance this goal, ODIP organizes international workshops to foster the development of common standards and develop prototypes to evaluate and test potential standards and interoperability solutions. ODIP includes major organizations engaged in ocean data stewardship in the EU, US, and Australia, supported by the International Oceanographic Data and Information Exchange (IODE). Within the broad scope of ODIP, R2R focuses on contributions in 4 key areas: ● Implement a 'Linked Open Data' approach to disseminate data and documentation, using existing World Wide Web Consortium (W3C) specifications and machine-readable formats. Exposing content as Linked Open Data will provide a simple mechanism for ODIP collaborators to browse and compare data sets among repositories. ● Map key vocabularies used by R2R to their European and Australian counterparts. The existing heterogeneity among terms inhibits data discoverability, as a user searching on the term with which s/he is familiar may not find all data of interest. Mapping key terms across the different ODIP partners, relying on the backbone thesaurus provided by the NERC Vocabulary Server

  11. A draft genome of the brown alga, Cladosiphon okamuranus, S-strain: a platform for future studies of ‘mozuku’ biology

    Science.gov (United States)

    Nishitsuji, Koki; Arimoto, Asuka; Iwai, Kenji; Sudo, Yusuke; Hisata, Kanako; Fujie, Manabu; Arakaki, Nana; Kushiro, Tetsuo; Konishi, Teruko; Shinzato, Chuya; Satoh, Noriyuki; Shoguchi, Eiichi

    2016-01-01

    The brown alga, Cladosiphon okamuranus (Okinawa mozuku), is economically one of the most important edible seaweeds, and is cultivated for market primarily in Okinawa, Japan. C. okamuranus constitutes a significant source of fucoidan, which has various physiological and biological activities. To facilitate studies of seaweed biology, we decoded the draft genome of C. okamuranus S-strain. The genome size of C. okamuranus was estimated as ∼140 Mbp, smaller than genomes of two other brown algae, Ectocarpus siliculosus and Saccharina japonica. Sequencing with ∼100× coverage yielded an assembly of 541 scaffolds with N50 = 416 kbp. Together with transcriptomic data, we estimated that the C. okamuranus genome contains 13,640 protein-coding genes, approximately 94% of which have been confirmed with corresponding mRNAs. Comparisons with the E. siliculosus genome identified a set of C. okamuranus genes that encode enzymes involved in biosynthetic pathways for sulfated fucans and alginate biosynthesis. In addition, we identified C. okamuranus genes for enzymes involved in phlorotannin biosynthesis. The present decoding of the Cladosiphon okamuranus genome provides a platform for future studies of mozuku biology. PMID:27501718

  12. Comparison of two US sheep scrapie isolates supports identification as separate strains

    Science.gov (United States)

    Scrapie is a naturally occurring transmissible spongiform encephalopathy (TSE) of sheep and goats. There are different strains of sheep scrapie that are associated with unique molecular, transmission, and phenotype characteristics, but very little is known about the potential presence of scrapie str...

  13. Effectiveness of Supportive Educative Learning programme on the level of strain experienced by caregivers of stroke patients in Thailand.

    Science.gov (United States)

    Oupra, R; Griffiths, R; Pryor, J; Mott, S

    2010-01-01

    In Thailand, the crude death rate from stroke is 10.9/100,000 population and increasing. Unlike Western countries where community rehabilitation programmes have been established to provide services following the acute stage of stroke recovery, there is no stroke rehabilitation team in the community in Thailand. Therefore, family caregivers are the primary source for ongoing care and support. While family members accompany patients during their hospitalisation, they receive little information about how to assist their relatives, and as a result feel inadequately trained, poorly informed and dissatisfied with the support that is available after discharge. Family caregivers report that they suffer both physically and psychologically and find themselves overwhelmed with strain, experiencing burden and exhaustion. This study aimed to develop and implement a nurse-led Supportive Educative Learning programme for family caregivers (SELF) of stroke survivors in Thailand and to evaluate the effect of the SELF programme on family caregiver's strain and quality of life. This was a non-randomised comparative study with concurrent controls, using a two-group pre-test and post-test design. A total of 140 stroke survivors and 140 family caregivers were recruited; 70 patients/caregiver pair in each group. Caregivers of patients admitted to the intervention hospital following an acute stroke received the intervention, while caregivers of patients admitted to the comparison hospital received the usual care provided at the hospital. The data were collected prior to discharge of the patients and after 3 months. The family caregivers in the intervention group had a significantly better quality of life than the comparison group (GHQ-28 at discharge t = 2.82, d.f. = 138, P = 0.006; and at 3 months t = 6.80, d.f. = 135, P Caregiver Strain Index at discharge t = 6.73, d.f. = 138, P caregiver of stroke survivors can reduce caregiver strain and enhance their quality of life.

  14. Effect of different types of prosthetic platforms on stress-distribution in dental implant-supported prostheses.

    Science.gov (United States)

    Minatel, Lurian; Verri, Fellippo Ramos; Kudo, Guilherme Abu Halawa; de Faria Almeida, Daniel Augusto; de Souza Batista, Victor Eduardo; Lemos, Cleidiel Aparecido Araujo; Pellizzer, Eduardo Piza; Santiago, Joel Ferreira

    2017-02-01

    A biomechanical analysis of different types of implant connections is relevant to clinical practice because it may impact the longevity of the rehabilitation treatment. Therefore, the objective of this study is to evaluate the Morse taper connections and the stress distribution of structures associated with the platform switching (PSW) concept. It will do this by obtaining data on the biomechanical behavior of the main structure in relation to the dental implant using the 3-dimensional finite element methodology. Four models were simulated (with each containing a single prosthesis over the implant) in the molar region, with the following specifications: M1 and M2 is an external hexagonal implant on a regular platform; M3 is an external hexagonal implant using PSW concept; and M4 is a Morse taper implant. The modeling process involved the use of images from InVesalius CT (computed tomography) processing software, which were refined using Rhinoceros 4.0 and SolidWorks 2011 CAD software. The models were then exported into the finite element program (FEMAP 11.0) to configure the meshes. The models were processed using NeiNastram software. The main results are that M1 (regular diameter 4mm) had the highest stress concentration area and highest microstrain concentration for bone tissue, dental implants, and the retaining screw (P<0.05). Using the PSW concept increases the area of the stress concentrations in the retaining screw (P<0.05) more than in the regular platform implant. It was concluded that the increase in diameter is beneficial for stress distribution and that the PSW concept had higher stress concentrations in the retaining screw and the crown compared to the regular platform implant. Copyright © 2016 Elsevier B.V. All rights reserved.

  15. Classification of Bartonella strains associated with straw-colored fruit bats (Eidolon helvum) across Africa using a multi-locus sequence typing platform.

    Science.gov (United States)

    Bai, Ying; Hayman, David T S; McKee, Clifton D; Kosoy, Michael Y

    2015-01-01

    Bartonellae are facultative intracellular bacteria and are highly adapted to their mammalian host cell niches. Straw-colored fruit bats (Eidolon helvum) are commonly infected with several bartonella strains. To elucidate the genetic diversity of these bartonella strains, we analyzed 79 bartonella isolates from straw-colored fruit bats in seven countries across Africa (Cameroon, Annobon island of Equatorial Guinea, Ghana, Kenya, Nigeria, Tanzania, and Uganda) using a multi-locus sequencing typing (MLST) approach based on nucleotide sequences of eight loci (ftsZ, gltA, nuoG, ribC, rpoB, ssrA, ITS, and 16S rRNA). The analysis of each locus but ribC demonstrated clustering of the isolates into six genogroups (E1 - E5 and Ew), while ribC was absent in the isolates belonging to the genogroup Ew. In general, grouping of all isolates by each locus was mutually supportive; however, nuoG, gltA, and rpoB showed some incongruity with other loci in several strains, suggesting a possibility of recombination events, which were confirmed by network analyses and recombination/mutation rate ratio (r/m) estimations. The MLST scheme revealed 45 unique sequence types (ST1 - 45) among the analyzed bartonella isolates. Phylogenetic analysis of concatenated sequences supported the discrimination of six phylogenetic lineages (E1 - E5 and Ew) corresponding to separate and unique Bartonella species. One of the defined lineages, Ew, consisted of only two STs (ST1 and ST2), and comprised more than one-quarter of the analyzed isolates, while other lineages contained higher numbers of STs with a smaller number of isolates belonging to each lineage. The low number of allelic polymorphisms of isolates belonging to Ew suggests a more recent origin for this species. Our findings suggest that at least six Bartonella species are associated with straw-colored fruit bats, and that distinct STs can be found across the distribution of this bat species, including in populations of bats which are

  16. Classification of Bartonella strains associated with straw-colored fruit bats (Eidolon helvum across Africa using a multi-locus sequence typing platform.

    Directory of Open Access Journals (Sweden)

    Ying Bai

    2015-01-01

    Full Text Available Bartonellae are facultative intracellular bacteria and are highly adapted to their mammalian host cell niches. Straw-colored fruit bats (Eidolon helvum are commonly infected with several bartonella strains. To elucidate the genetic diversity of these bartonella strains, we analyzed 79 bartonella isolates from straw-colored fruit bats in seven countries across Africa (Cameroon, Annobon island of Equatorial Guinea, Ghana, Kenya, Nigeria, Tanzania, and Uganda using a multi-locus sequencing typing (MLST approach based on nucleotide sequences of eight loci (ftsZ, gltA, nuoG, ribC, rpoB, ssrA, ITS, and 16S rRNA. The analysis of each locus but ribC demonstrated clustering of the isolates into six genogroups (E1 - E5 and Ew, while ribC was absent in the isolates belonging to the genogroup Ew. In general, grouping of all isolates by each locus was mutually supportive; however, nuoG, gltA, and rpoB showed some incongruity with other loci in several strains, suggesting a possibility of recombination events, which were confirmed by network analyses and recombination/mutation rate ratio (r/m estimations. The MLST scheme revealed 45 unique sequence types (ST1 - 45 among the analyzed bartonella isolates. Phylogenetic analysis of concatenated sequences supported the discrimination of six phylogenetic lineages (E1 - E5 and Ew corresponding to separate and unique Bartonella species. One of the defined lineages, Ew, consisted of only two STs (ST1 and ST2, and comprised more than one-quarter of the analyzed isolates, while other lineages contained higher numbers of STs with a smaller number of isolates belonging to each lineage. The low number of allelic polymorphisms of isolates belonging to Ew suggests a more recent origin for this species. Our findings suggest that at least six Bartonella species are associated with straw-colored fruit bats, and that distinct STs can be found across the distribution of this bat species, including in populations of bats which are

  17. Effect of 5-HT2A Receptor Polymorphisms, Work Stressors, and Social Support on Job Strain among Petroleum Workers in Xinjiang, China.

    Science.gov (United States)

    Jiang, Yu; Tang, Jinhua; Li, Rong; Zhao, Junling; Song, Zhixin; Ge, Hua; Lian, Yulong; Liu, Jiwen

    2016-12-19

    Previous studies have shown that work stressors and social support influence job strain. However, few studies have examined the impact of individual differences on job strain. In Xinjiang, there are a large number of petroleum workers in arid deserts. The present study investigated the effects of work stressors, social support, and 5-hydroxytryptamine receptor (5-HTR2A) genotype on the etiology of job strain among petroleum workers in Xinjiang. A cross-sectional study was carried out between January and August 2013. A total of 700 workers were selected by a three-stage stratified sampling method. 5-HTR2A genotypes were determined with the SNaPshot single nucleotide polymorphism assay. Work stressors and job strain were evaluated with the Occupational Stress Inventory-Revised questionnaire. Social support was assessed with the Chinese Social Support Rating Scale. Work overload and responsibility were significantly associated with job strain. Low social support was associated with severe vocational and interpersonal strain. High social support was a protective factor against job strain (odds ratio (OR) = 0.32, 95% confidence interval (CI): 0.14-0.76). The CC genotype of rs6313 and the AA genotype of rs2070040 were linked to severe vocational strain. Ordinal logistic regression analysis revealed that the CC genotype of rs6313 was linked to higher risk of job strain than the TT genotype (OR = 1.88, 95% CI: 1.10-3.23). These data provide evidence that work stressors, low social support, and 5-HTR2A gene polymorphism contributes to the risk of job strain.

  18. Effect of 5-HT2A Receptor Polymorphisms, Work Stressors, and Social Support on Job Strain among Petroleum Workers in Xinjiang, China

    Science.gov (United States)

    Jiang, Yu; Tang, Jinhua; Li, Rong; Zhao, Junling; Song, Zhixin; Ge, Hua; Lian, Yulong; Liu, Jiwen

    2016-01-01

    Previous studies have shown that work stressors and social support influence job strain. However, few studies have examined the impact of individual differences on job strain. In Xinjiang, there are a large number of petroleum workers in arid deserts. The present study investigated the effects of work stressors, social support, and 5-hydroxytryptamine receptor (5-HTR2A) genotype on the etiology of job strain among petroleum workers in Xinjiang. A cross-sectional study was carried out between January and August 2013. A total of 700 workers were selected by a three-stage stratified sampling method. 5-HTR2A genotypes were determined with the SNaPshot single nucleotide polymorphism assay. Work stressors and job strain were evaluated with the Occupational Stress Inventory-Revised questionnaire. Social support was assessed with the Chinese Social Support Rating Scale. Work overload and responsibility were significantly associated with job strain. Low social support was associated with severe vocational and interpersonal strain. High social support was a protective factor against job strain (odds ratio (OR) = 0.32, 95% confidence interval (CI): 0.14–0.76). The CC genotype of rs6313 and the AA genotype of rs2070040 were linked to severe vocational strain. Ordinal logistic regression analysis revealed that the CC genotype of rs6313 was linked to higher risk of job strain than the TT genotype (OR = 1.88, 95% CI: 1.10–3.23). These data provide evidence that work stressors, low social support, and 5-HTR2A gene polymorphism contributes to the risk of job strain. PMID:27999378

  19. A Brief Analysis of Centralized Support Model in Uniifed Payment Platform%统一支付平台集中支撑模式浅析

    Institute of Scientific and Technical Information of China (English)

    李叶林

    2014-01-01

    With the rapid development of mobile Internet, traditional offline payment methods provided by communication operators cannot meet personalized payment demands of customers, and customers have more and more available options on payment channels and methods. A unified payment platform was built using centralized support model under this background, which can access commercial bank systems, the third party payment platform and e-commerce platform. It can complete operators’ payment system and achieve comprehensive improvement of payment ability.%随着移动互联网的快速发展,通信运营商传统的线下实体渠道缴纳费用的模式已逐渐无法满足客户个性化的充值缴费需求,客户可选择的支付渠道和方式正呈现出多样化发展的趋势。在此背景下,提出了建立一个可以接入商业银行系统、第三方支付平台、电商平台等机构且采用集中化支撑的统一支付平台,从而完善运营商缴费充值体系,实现缴费能力的全面提升。

  20. Virtual environments in cancer care: Pilot-testing a three-dimensional web-based platform as a tool for support in young cancer patients.

    Science.gov (United States)

    Høybye, Mette Terp; Olsen, Pia Riis; Hansson, Helena Eva; Spiegel, David; Bennetsen, Henrik; Cheslack-Postava, Ewen

    2016-11-28

    Bringing virtual environments into cancer support may offer a particular potential to engage patients and increase adherence to treatment. Developing and pilot-testing an online real-time multi-user three-dimensional platform, this study tested the use of an early prototype of the platform among adolescent and young adult cancer patients. Data were collected with an online questionnaire and using ethnographic methods of participant observation. The adolescent and young adult patients tested basic features of the virtual environment and some conducted brief in-world interactions with fellow patients during hospitalization. They had no reservations about using the technology and shared their ideas about its use. Our pilot test pointed to a number of areas of development for virtual environment applications as potential platforms for medical or behavioral interventions in cancer care. Overall, the results demonstrate the need for high user involvement in the development of such interventions and early testing of intervention designs. © The Author(s) 2016.

  1. Protocol for a Randomized Controlled Trial of Proactive Web-Based Versus Telephone-Based Information and Support: Can Electronic Platforms Deliver Effective Care for Lung Cancer Patients?

    Science.gov (United States)

    Boyes, Allison W; O'Brien, Lorna; Baker, Amanda L; Henskens, Frans A; Clinton-McHarg, Tara; Bellamy, Douglas; Colburn, Glenda; Rose, Shiho; Cox, Martine E; Fradgley, Elizabeth A; Baird, Hannah; Barker, Daniel

    2016-01-01

    Background Community-based services such as telephone support lines can provide valuable informational, emotional, and practical support for cancer patients via telephone- or Web-based (live chat or email) platforms. However, very little rigorous research has examined the efficacy of such services in improving patient outcomes. Objective This study will determine whether: proactive telephone or Web-delivered support produces outcomes superior to printed information; and Web-delivered support produces outcomes comparable to telephone support. Methods A consecutive sample of 501 lung cancer outpatients will be recruited from 50 Australian health services to participate in a patient-randomized controlled trial (RCT). Eligible individuals must: be 18 years or older; have received a lung cancer diagnosis (including mesothelioma) within the previous 4 months; have an approximate life expectancy of at least 6 months; and have Internet access. Participants will be randomly allocated to receive: (1) an information booklet, (2) proactive telephone support, or (3) proactive Web support, chat, and/or email. The primary patient outcomes will be measured by the General Health Questionnaire (GHQ-12) and Health Education and Impact Questionnaire (heiQ) at 3 and 6 months post recruitment. The acceptability of proactive recruitment strategies will also be assessed. Results It is hypothesized that participants receiving telephone or Web support will report reduced distress (GHQ-12 scores that are 0.3 standard deviations (SD) lower) and greater self-efficacy (heiQ scores that are 0.3 SDs higher) than participants receiving booklets. Individuals receiving Web support will report heiQ scores within 0.29 SDs of individuals receiving telephone support. Conclusions If proven effective, electronic approaches such as live-chat and email have the potential to increase the accessibility and continuity of supportive care delivered by community-based services. This evidence may also inform the

  2. The main functions of network teaching support platform in teaching%网络教学支撑平台在教学中的主要功能

    Institute of Scientific and Technical Information of China (English)

    付建清

    2016-01-01

    With the popularity of network teaching, use network teaching support platform function, in order to realize the sharing of quality teaching resources, will play an increasingly important role in the construction of educational information.%随着网络教学的普及,利用网络教学支撑平台的功能,以实现优质教学资源的共享,将在教育信息化建设中发挥着越来越重要的作用。

  3. Developing Knowledge-Based Citizen Participation Platform to Support Smart City Decision Making: The Smarticipate Case Study

    Directory of Open Access Journals (Sweden)

    Zaheer Khan

    2017-04-01

    Full Text Available Citizen participation for social innovation and co-creating urban regeneration proposals can be greatly facilitated by innovative IT systems. Such systems can use Open Government Data, visualise urban proposals in 3D models and provide automated feedback on the feasibility of the proposals. Using such a system as a communication platform between citizens and city administrations provides an integrated top-down and bottom-up urban planning and decision-making approach to smart cities. However, generating automated feedback on citizens’ proposals requires modelling domain-specific knowledge i.e., vocabulary and rules, which can be applied on spatial and temporal 3D models. This paper presents the European Commission funded H2020 smarticipate project that aims to achieve the above challenge by applying it on three smart cities: Hamburg, Rome and RBKC-London. Whilst the proposed system architecture indicates various innovative features, a proof of concept of the automated feedback feature for the Hamburg use case ‘planting trees’ is demonstrated. Early results and lessons learned show that it is feasible to provide automated feedback on citizen-initiated proposals on specific topics. However, it is not straightforward to generalise this feature to cover more complex concepts and conditions which require specifying comprehensive domain languages, rules and appropriate tools to process them. This paper also highlights the strengths of the smarticipate platform, discusses challenges to realise its different features and suggests potential solutions.

  4. Towards a cross-platform software framework to support end-to-end hydrometeorological sensor network deployment

    Science.gov (United States)

    Celicourt, P.; Sam, R.; Piasecki, M.

    2016-12-01

    Global phenomena such as climate change and large scale environmental degradation require the collection of accurate environmental data at detailed spatial and temporal scales from which knowledge and actionable insights can be derived using data science methods. Despite significant advances in sensor network technologies, sensors and sensor network deployment remains a labor-intensive, time consuming, cumbersome and expensive task. These factors demonstrate why environmental data collection remains a challenge especially in developing countries where technical infrastructure, expertise and pecuniary resources are scarce. In addition, they also demonstrate the reason why dense and long-term environmental data collection has been historically quite difficult. Moreover, hydrometeorological data collection efforts usually overlook the (critically important) inclusion of a standards-based system for storing, managing, organizing, indexing, documenting and sharing sensor data. We are developing a cross-platform software framework using the Python programming language that will allow us to develop a low cost end-to-end (from sensor to publication) system for hydrometeorological conditions monitoring. The software framework contains provision for sensor, sensor platforms, calibration and network protocols description, sensor programming, data storage, data publication and visualization and more importantly data retrieval in a desired unit system. It is being tested on the Raspberry Pi microcomputer as end node and a laptop PC as the base station in a wireless setting.

  5. Temperature and salinity profiles from CTD casts from the VALKIRIYA and other PLATFORMS from a World-Wide Distribution in support of the Integrated Global Ocean Services System (IGOSS) from 01 January 1991 to 31 January 1991 (NODC Accession 9100035)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — CTD and other data were collected from the VALKIRIYA and other PLATFORMS in support of the Integrated Global Ocean Services System (IGOSS). Data were collected by US...

  6. Temperature and salinity profiles from CTD casts from the PARIZEAU and other PLATFORMS from a World-Wide distribution in support of the Integrated Global Ocean Services System (IGOSS) from 01 October 1988 to 31 October 1988 (NODC Accession 8800296)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — CTD and other data were collected from the PARIZEAU and other PLATFORMS in support of the Integrated Global Ocean Services System (IGOSS). Data were collected by US...

  7. Temperature and salinity profiles from CTD casts from the VALDIVIA and other PLATFORMS from a World-Wide Distribution in support of the Integrated Global Ocean Services System (IGOSS) from 01 April 1991 to 30 April 1991 (NODC Accession 9100087)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — CTD and other data were collected from the VALDIVIA and other PLATFORMS in support of the Integrated Global Ocean Services System (IGOSS). Data were collected by US...

  8. Temperature and salinity profiles from CTD casts from the ARGOS and other PLATFORMS from a World-Wide Distribution in support of the Integrated Global Ocean Services System (IGOSS) from 01 November 1989 to 30 November 1989 (NODC Accession 8900297)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — CTD and other data were collected from the ARGOS and other PLATFORMS in support of the Integrated Global Ocean Services System (IGOSS). Data were collected by US...

  9. Wave spectra, meteorological, and other data from FIXED PLATFORMS from the North Atlantic Ocean and other locations in support of the Tropical Ocean Global Atmosphere (TOGA) project from 01 April 1987 to 29 April 1987 (NODC Accession 8700208)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Wave spectra, meteorological, and other data were collected from FIXED PLATFORMS. Data were collected by the National Data Buoy Center (NDBC) in support of the...

  10. Temperature profiles from expendable bathythermograph (XBT) casts from the BARTLETT and Other Platforms in the North Pacific Ocean in support of the Integrated Global Ocean Services System (IGOSS) project from 14 March 1974 to 04 May 1974 (NODC Accession 7400432)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — XBT data were collected from the BARTLETT and Other Platforms in support of the Integrated Global Ocean Services System (IGOSS) project. Data were collected by the...

  11. Acceptability and use of a virtual support group for HIV-positive youth in Khayelitsha, Cape Town using the MXit social networking platform.

    Science.gov (United States)

    Henwood, Ruth; Patten, Gabriela; Barnett, Whitney; Hwang, Bella; Metcalf, Carol; Hacking, Damian; Wilkinson, Lynne

    2016-07-01

    Médecins Sans Frontières supports human immunodeficiency virus (HIV)-infected youth, aged 12-25 years, at a clinic in Khayelitsha, South Africa. Patients are enrolled in youth clubs, and provided with a virtual chat room, using the cell-phone-based social networking platform, MXit, to support members between monthly/bimonthly club meetings. The acceptability and uptake of MXit was assessed. MXit was facilitated by lay counsellors, was password protected, and participants could enter and leave at will. Club members were asked to complete self-administered questionnaires and participate in two focus-group discussions. In total, 60 club members completed the questionnaire, and 12 participated in the focus groups. Fifty-eight percentage were aged 23-25 years, 63% were female and 83% had a cell phone. Sixty percentage had used MXit before, with 38% having used it in the past month. Sixty-five percentage were aware of the chat-room and 39% knew how to access it. Thirty-four percentage used the chat-room at least once, 20% had visited the chat-room in the past month, and 29% had used MXit to have private conversations with other club members. Fifty-seven percentage used the chat-room to get advice, and 84% of all respondents felt that offering a service outside the youth club meetings was important and would like to see one to continue. The cost of using social media platforms was an issue with some, as well as the need for anonymity. Preference for other platforms, logistical obstacles, or loss of interest contributed to non-use. Reported usage of the MXit chat-room was low, but participants indicated acceptance of the programme and their desire to interact with their peers through social media. Suggestions to improve the platform included accessible chat histories, using more popular platforms such as Facebook or WhatsApp, and to have topical discussions where pertinent information for youth is provided.

  12. The SmartH2O project: a platform supporting residential water management through smart meters and data intensive modeling

    Science.gov (United States)

    Cominola, A.; Nanda, R.; Giuliani, M.; Piga, D.; Castelletti, A.; Rizzoli, A. E.; Maziotis, A.; Garrone, P.; Harou, J. J.

    2014-12-01

    Designing effective urban water demand management strategies at the household level does require a deep understanding of the determinants of users' consumption. Low resolution data on residential water consumption, as traditionally metered, can only be used to model consumers' behavior at an aggregate level whereas end uses breakdown and the motivations and individual attitudes of consumers are hidden. The recent advent of smart meters allows gathering high frequency consumption data that can be used both to provide instantaneous information to water utilities on the state of the network and continuously inform the users on their consumption and savings. Smart metered data also allow for the characterization of water end uses: this information, coupled with users' psychographic variables, constitutes the knowledge basis for developing individual and multi users models, through which water utilities can test the impact of different management strategies. SmartH2O is an EU funded project which aims at creating an ICT platform able to (i) capture and store quasi real time, high resolution residential water usage data measured with smart meters, (ii) infer the main determinants of residential water end uses and build customers' behavioral models and (iii) predict how the customer behavior can be influenced by various water demand management strategies, spanning from dynamic water pricing schemes to social awareness campaigns. The project exploits a social computing approach for raising users' awareness about water consumption and pursuing water savings in the residential sector. In this work, we first present the SmartH2O platform and data collection, storage and analysis components. We then introduce some preliminary models and results on total water consumption disaggregation into end uses and single user behaviors using innovative fully automated algorithms and overcoming the need of invasive metering campaigns at the fixture level.

  13. The Theoretical Study of the Beams Supported on a Straining Environment as an Interaction Problem Soil - Structure - Infrastructure Interaction

    Directory of Open Access Journals (Sweden)

    Ana-Raluca Chiriac

    2006-01-01

    Full Text Available Between structure, infrastructure (foundation and soil there is an effective interaction, which has to be taken into account as correctly as possible every time we do the calculation. This effective interaction can be analysed in a global form, considering on one hand the entire building, and on the other hand the soil -- establishment surface, or in an analytical form: we consider first the soil -- infrastructure (foundation interaction and then the structure -- infrastructure one. Without considering the interaction, we cannot make neither the calculation (for the soil according to the limiting deformation state which has to be compatible with the structure’s resistance system, nor calculation for the limiting resistance state, because the correct distribution of efforts along the contact surface between the soil and the structure is unknown, so we cannot determine the zones of plastical equilibrium in the soil massive and the conditions of limited equilibrium. Also, without considering the infrastructure, we cannot correctly calculate the efforts and the deformations which may occur in all resistance elements of the building. Therefore, we cannot talk about limiting state calculation without considering the interaction between the soil and the structure itself. The problem of interaction between building, on one hand and soil foundation, on the other hand, is not approached very much in the specialized literature, because of the big difficulties raised by summarizing all the factors that describe the structure and the environment, which would be more accessible to a practical calculation. A lot of buildings or elements of buildings standing on the soil or on another environment with finite rigidity can be taken into account as beams supported on a straining environment, (continuous foundations, resistance walls, longitudinal and transversal membranes of civil and industrial buildings, hydrotechnic works. Therefore, in the present paper we

  14. CYCLOPS: A mobile robotic platform for testing and validating image processing and autonomous navigation algorithms in support of artificial vision prostheses.

    Science.gov (United States)

    Fink, Wolfgang; Tarbell, Mark A

    2009-12-01

    While artificial vision prostheses are quickly becoming a reality, actual testing time with visual prosthesis carriers is at a premium. Moreover, it is helpful to have a more realistic functional approximation of a blind subject. Instead of a normal subject with a healthy retina looking at a low-resolution (pixelated) image on a computer monitor or head-mounted display, a more realistic approximation is achieved by employing a subject-independent mobile robotic platform that uses a pixelated view as its sole visual input for navigation purposes. We introduce CYCLOPS: an AWD, remote controllable, mobile robotic platform that serves as a testbed for real-time image processing and autonomous navigation systems for the purpose of enhancing the visual experience afforded by visual prosthesis carriers. Complete with wireless Internet connectivity and a fully articulated digital camera with wireless video link, CYCLOPS supports both interactive tele-commanding via joystick, and autonomous self-commanding. Due to its onboard computing capabilities and extended battery life, CYCLOPS can perform complex and numerically intensive calculations, such as image processing and autonomous navigation algorithms, in addition to interfacing to additional sensors. Its Internet connectivity renders CYCLOPS a worldwide accessible testbed for researchers in the field of artificial vision systems. CYCLOPS enables subject-independent evaluation and validation of image processing and autonomous navigation systems with respect to the utility and efficiency of supporting and enhancing visual prostheses, while potentially reducing to a necessary minimum the need for valuable testing time with actual visual prosthesis carriers.

  15. Job strain and supervisor support in primary care health centres and glycaemic control among patients with type 2 diabetes: a cross-sectional study

    OpenAIRE

    Koponen, Anne; Vahtera, Jussi; Pitkäniemi, Janne; Virtanen, Marianna; Pentti, Jaana; Simonsen-Rehn, Nina; Kivimäki, Mika; Suominen, Sakari

    2013-01-01

    Objectives This study investigates associations between healthcare personnel's perceived job strain, supervisor support and the outcome of care in terms of glycaemic control among patients with type 2 diabetes. Design A cross-sectional study from 2006. Setting 18 primary care health centres (HCs) from five municipalities in Finland. Participants Aggregated survey data on perceived job strain and supervisor support from healthcare personnel (doctors, n=122, mean age 45.5 years, nurses, n=300, ...

  16. Autonomous Operations Planner: A Flexible Platform for Research in Flight-Deck Support for Airborne Self-Separation

    Science.gov (United States)

    Karr, David A.; Vivona, Robert A.; DePascale, Stephen M.; Wing, David J.

    2012-01-01

    The Autonomous Operations Planner (AOP), developed by NASA, is a flexible and powerful prototype of a flight-deck automation system to support self-separation of aircraft. The AOP incorporates a variety of algorithms to detect and resolve conflicts between the trajectories of its own aircraft and traffic aircraft while meeting route constraints such as required times of arrival and avoiding airspace hazards such as convective weather and restricted airspace. This integrated suite of algorithms provides flight crew support for strategic and tactical conflict resolutions and conflict-free trajectory planning while en route. The AOP has supported an extensive set of experiments covering various conditions and variations on the self-separation concept, yielding insight into the system s design and resolving various challenges encountered in the exploration of the concept. The design of the AOP will enable it to continue to evolve and support experimentation as the self-separation concept is refined.

  17. Adaptation of a web-based, open source electronic medical record system platform to support a large study of tuberculosis epidemiology

    Directory of Open Access Journals (Sweden)

    Fraser Hamish SF

    2012-11-01

    Full Text Available Abstract Background In 2006, we were funded by the US National Institutes of Health to implement a study of tuberculosis epidemiology in Peru. The study required a secure information system to manage data from a target goal of 16,000 subjects who needed to be followed for at least one year. With previous experience in the development and deployment of web-based medical record systems for TB treatment in Peru, we chose to use the OpenMRS open source electronic medical record system platform to develop the study information system. Supported by a core technical and management team and a large and growing worldwide community, OpenMRS is now being used in more than 40 developing countries. We adapted the OpenMRS platform to better support foreign languages. We added a new module to support double data entry, linkage to an existing laboratory information system, automatic upload of GPS data from handheld devices, and better security and auditing of data changes. We added new reports for study managers, and developed data extraction tools for research staff and statisticians. Further adaptation to handle direct entry of laboratory data occurred after the study was launched. Results Data collection in the OpenMRS system began in September 2009. By August 2011 a total of 9,256 participants had been enrolled, 102,274 forms and 13,829 laboratory results had been entered, and there were 208 users. The system is now entirely supported by the Peruvian study staff and programmers. Conclusions The information system served the study objectives well despite requiring some significant adaptations mid-stream. OpenMRS has more tools and capabilities than it did in 2008, and requires less adaptations for future projects. OpenMRS can be an effective research data system in resource poor environments, especially for organizations using or considering it for clinical care as well as research.

  18. SeaSketch: Implementation of a Decision-Support Platform for a Channel Islands National Marine Sanctuary Multi-sector Working Group

    Science.gov (United States)

    Goldberg, G.; McClintock, W.

    2016-12-01

    Effective interagency and cross-sector coordination is essential to ecosystem based management which depends on processes characterized by collaboration and science-based information. Many technological barriers that exist in the development of science-based management plans are closely tied to process challenges, such as the sharing of data and information or the inclusion of parties with varied levels of technical experience. The Channel Islands National Marine Sanctuary has convened a diverse working group to develop recommendations for the management of marine shipping in and around the Santa Barbara Channel, as well as recommendations regarding research needs and outreach strategies. Working group members take a multi-issue approach with four distinct goals related to the reduction of ship strikes on whales, emissions and air quality, conflicting ocean uses, and issues of navigational safety. Members range from industry representatives, scientists, and multiple local and federal government entities. The recommended management plans will be based in the best-available science, and will build off of previous efforts, making this an interesting case study of adaptive management. In addition to support from the Sanctuary and professional facilitators, the group is using a decision-support platform, SeaSketch (safepassage.seasketch.org). SeaSketch is a web-based GIS that supports collaborative science-based marine spatial planning (MSP). Each feature supports a step of the MSP process, from data gathering, identification of data needs, the design of spatial plans, evaluation of those plans with analytics, and map-based forums that facilitate data-driven discussions. Working group members are able to access these tools to explore management options and collaborate remotely, in addition to using the platform during in-person meetings and webinars. Empowering diverse audiences to engage in the design of science-based plans is of key importance to developing ecosystem

  19. Farm Management Support on Cloud Computing Platform: A System for Cropland Monitoring Using Multi-Source Remotely Sensed Data

    Science.gov (United States)

    Coburn, C. A.; Qin, Y.; Zhang, J.; Staenz, K.

    2015-12-01

    Food security is one of the most pressing issues facing humankind. Recent estimates predict that over one billion people don't have enough food to meet their basic nutritional needs. The ability of remote sensing tools to monitor and model crop production and predict crop yield is essential for providing governments and farmers with vital information to ensure food security. Google Earth Engine (GEE) is a cloud computing platform, which integrates storage and processing algorithms for massive remotely sensed imagery and vector data sets. By providing the capabilities of storing and analyzing the data sets, it provides an ideal platform for the development of advanced analytic tools for extracting key variables used in regional and national food security systems. With the high performance computing and storing capabilities of GEE, a cloud-computing based system for near real-time crop land monitoring was developed using multi-source remotely sensed data over large areas. The system is able to process and visualize the MODIS time series NDVI profile in conjunction with Landsat 8 image segmentation for crop monitoring. With multi-temporal Landsat 8 imagery, the crop fields are extracted using the image segmentation algorithm developed by Baatz et al.[1]. The MODIS time series NDVI data are modeled by TIMESAT [2], a software package developed for analyzing time series of satellite data. The seasonality of MODIS time series data, for example, the start date of the growing season, length of growing season, and NDVI peak at a field-level are obtained for evaluating the crop-growth conditions. The system fuses MODIS time series NDVI data and Landsat 8 imagery to provide information of near real-time crop-growth conditions through the visualization of MODIS NDVI time series and comparison of multi-year NDVI profiles. Stakeholders, i.e., farmers and government officers, are able to obtain crop-growth information at crop-field level online. This unique utilization of GEE in

  20. 新型机动电源保障平台研究%Research on Novel Mobile Power Supply Support Platform

    Institute of Scientific and Technical Information of China (English)

    颜南明; 张豫南; 胡国庆

    2012-01-01

    In order to satisfy the special requirements of power supply support for army equipment, a novel power supply support platform consisting of engine-generator sets, electric power converter, battery and AC (Alternate Current) motor drive system is proposed; the main subsystems are designed and developed. Based on 1-ton military wheel vehicle, a novel mobile power supply support platform with 4 x 4 hybrid electric drive system is completed. Test results of the sample platfrom prove that what achieved in this paper not only satisfy requirement such as strong maneuverability, multi-function, but also be excellent in manipulation and control.%为满足陆军装备对电源保障的特殊要求,提出了一种由发动机-发电机组、电功率变换器、蓄电池、交流电机驱动系统组成的新型机动电源保障平台,对平台中主要子系统进行了设计和开发,完成了一吨级4×4混合动力新型机动电源保障平台的研制。试验结果表明:研究成果不仅实现了保障平台机动能力强、功能多等要求,而且具有良好的操控性。

  1. A real-time platform for monitoring schistosomiasis transmission supported by Google Earth and a web-based geographical information system.

    Science.gov (United States)

    Yang, Kun; Sun, Le-Ping; Huang, Yi-Xin; Yang, Guo-Jing; Wu, Feng; Hang, De-Rong; Li, Wei; Zhang, Jian-Feng; Liang, Yong-Sheng; Zhou, Xiao-Nong

    2012-05-01

    A basic framework for the rapid assessment of the risk for schistosomiasis was developed by combining spatial data from Google Earth® with a geographical information system (GIS) package, bundling the modules together with an Internet connection into a WebGIS platform. It operates through functions such as "search", "evaluation", "risk analysis" and "prediction" and is primarily aimed to be a dynamic, early-warning system (EWS) providing user-friendly, evidence-based, near real-time awareness of the status of an important endemic disease. It contributes to rapid information-sharing at all levels of decision-making, facilitating "point-of-care" response, i.e. treatment provided at newly discovered transmission sites. The experience using the platform is encouraging and it has the potential to improve support systems and strengthen schistosomiasis control activities, in particular with regard to surveillance and EWS. It can quickly and intuitively locate early, high-risk areas, retrieve all important data needed as well as provide detailed, up-to-date information on the performance of the control programme. This WebGIS, the first of its kind in the People's Republic of China, is not only applicable for schistosomiasis but can easily be adapted for improving control of any endemic disease in any geographical area.

  2. Strain and plastic composite support (PCS) selection for vitamin K (Menaquinone-7) production in biofilm reactors.

    Science.gov (United States)

    Mahdinia, Ehsan; Demirci, Ali; Berenjian, Aydin

    2017-06-30

    Menaquinone-7 (MK-7), a subtype of vitamin K, has received a significant attention due to its effect on improving bone and cardiovascular health. Current fermentation strategies, which involve static fermentation without aeration or agitation, are associated with low productivity and scale-up issues and hardly justify the commercial production needs of this vitamin. Previous studies indicate that static fermentation is associated with pellicle and biofilm formations, which are critical for MK-7 secretion while posing significant operational issues. Therefore, the present study is undertaken to evaluate the possibility of using a biofilm reactor as a new strategy for MK-7 fermentation. Bacillus species, namely, Bacillus subtilis natto, Bacillus licheniformis, and Bacillus amyloliquifaciens as well as plastic composite, supports (PCS) were investigated in terms of MK-7 production and biofilm formation. Results show the possibility of using a biofilm reactor for MK-7 biosynthesis. Bacillus subtilis natto and soybean flour yeast extract PCS in glucose medium were found as the most potent combination for production of MK-7 as high as 35.5 mg/L, which includes both intracellular and extracellular MK-7.

  3. High-resolution air pollution modeling for urban environments in support of dense multi-platform networks

    Science.gov (United States)

    Berchet, Antoine; Zink, Katrin; Arfire, Adrian; Marjovi, Ali; Martinoli, Alcherio; Emmenegger, Lukas; Brunner, Dominik

    2015-04-01

    As the fraction of people living in urban areas is rapidly increasing worldwide, the impact of air quality on human health in cities is a growing concern not only in developing countries but also in Europe despite the achievements of European air quality legislation. One obstacle to the quantitative assessment of the connections between health and air quality is the very high temporal and spatial variability of air pollutant concentrations within cities. Yet, an important issue for obtaining accurate and spatially highly resolved air pollution data is the trade-off between the high costs of accurate air pollution sensors and the number of such devices required for succinctly monitoring a given geographical area. The OpenSense 2 project aims at establishing air quality data at very high temporal and spatial resolution in the cities of Lausanne and Zurich in Switzerland in order to provide reliable information for epidemiologic studies and for the design of air pollution controls and urban planning. Towards this goal, observations from both stationary reference monitoring stations and low-cost mobile sensors (including sensing platforms anchored on public transport vehicles) are combined with high-resolution air quality modeling throughout the two cities. As a first step, we simulate the 3-dimensional, high-resolution dispersion and distribution of key pollutants using the GRAMM/GRAL modeling system. The GRAMM meteorological meso-scale model calculates wind fields at 100 m resolution accounting for the complex topography and land use within and around the two cities. GRAMM outputs are then used to drive the building-resolving dispersion model GRAL at 5-10m resolution. Further key inputs for GRAL are high resolution emission inventories and the 3-D building structure which are available for both cities. Here, in order to evaluate the ability of the GRAMM/GRAL modeling system to reproduce air pollutant distributions within the two cities of Lausanne and Zurich, we

  4. Assessing the Influence of Climate Extremes on Ecosystems and Human Health in Southwestern Amazon Supported by the PULSE-Brazil Platform

    DEFF Research Database (Denmark)

    Aragão, Luiz E O C; Marengo, Jose; Cox, Peter

    2016-01-01

    -environmental disasters such as the impacts of droughts and consequent increases in fire detections on the incidence of respiratory diseases, and 2) evaluating the impacts of temperature increases in combination with rainfall seasonality upon the incidence of Dengue fever. Based on data available in PULSE-Brazil platform...... a conceptual pathway for promoting the interaction between science and policy during the process of producing a tool that allows the understating of climate-relate processes. Our results clearly demonstrated that ecosystems are under increased fire risk in the future that will, in turn, affect the health...... region. We expect that PULSE-Brazil will serve not only as a technical tool for supporting governance, management, mitigation and long-term adaptation plans for climate impacts and natural disasters, but also will take advantage of its graphical capabilities to be an instructive vehicle that facilitates...

  5. SMART PLATFORM FOR SUPPORT ISSUES AT THE FIRST AND LAST MILE IN THE SUPPLY CHAIN - THE CONCEPT OF THE S-MILE PROJECT

    Directory of Open Access Journals (Sweden)

    Marcin STANIEK

    2016-09-01

    Full Text Available The concept of an innovative support tool for freight transport used in planning, organization and realization is presented in this paper. In addition to the basic functions of a fleet management tool, the educative approach towards environmentally friendly behaviour will be based on promoting ecological solutions, such as unconventionally powered cars, e.g., electric vehicles (EVs. The suggested criteria for a routing algorithm, which will be implemented in the freight transport planner tool, not only allows routing in relation to time and cost criteria, but also the criterion regarding the limitation of emissions of harmful factors. The implementation of innovative the S-mile platform gives rise to environmentally friendly cognition behaviour in the freight transport sector. This is a fundamental aspect to its application, which could help to move the planning, organization and realization of freight transport in the direction of more environmental friendly solutions

  6. 宁夏客户服务支撑平台的建设和应用%The construction and application of customer service support platform in Ningxia

    Institute of Scientific and Technical Information of China (English)

    李靖波

    2013-01-01

      介绍了客户服务支撑平台的架构、功能及应用情况。客户服务支撑平台包括智能故障抢修管理、停电可视化管理、营销服务资源可视化管理、业扩流程交互等功能模块,以解决95598热线服务调度业务的“盲调”现状为出发点,实现了95598热线服务与客户现场、故障抢修现场,营销业扩报装业务与现场业务等的信息互动目的,改变了传统的95598热线服务方式,提高了客户服务能力和服务手段。%Customer service support platform architecture, function and application situation are introduced in this paper. Cus-tomer service support platform includes intelligent fault repair man-agement, power outages, visual management, marketing, service re-source visual management, industry expansion process interac-tions, such as functional modules, to solve the 95598 hotline ser-vice scheduling "blind" the status quo as the starting point of the business, to achieve the 95598 hotline service site, fault repair site with the customer, the marketing industry expansion of new busi-ness with the business purpose of information interaction, changed the traditional way of 95598 hotline service, improve customer ser-vice capabilities and service means.

  7. Discussion on Application Supporting Platform of Water Resources Information System%水利信息系统应用支撑平台探讨

    Institute of Scientific and Technical Information of China (English)

    付静; 程益联

    2014-01-01

    随着水利信息化快速发展,水利信息共享困难、业务割据的问题已成为制约信息化发展的瓶颈,为此,必须开展水利信息化资源整合共享,其中,建设水利信息系统统一的应用支撑平台是资源整合共享的关键。详细介绍应用支撑平台的定位、组成、主要功能及服务方式,初步探讨水利云下的应用支撑平台架构组件及应用,确保水利信息系统的互联互通、信息共享、业务协同。%With the rapid development of water resources informatization, the problems of sharing difficulties, business separatist have become a bottleneck restricting the development of informationization. Therefore, resource integration and sharing about water resources informatization must be carried out. The key is constructing a unified application supporting platform of water resources information system. This paper introduces the location, composition, main functions and service modes in detail, preliminary discusses on the support platform architecture components and application under the cloud, in order to ensure interoperability, sharing and business collaboration of water resources information system.

  8. Platform Constellations

    DEFF Research Database (Denmark)

    Staykova, Kalina Stefanova; Damsgaard, Jan

    2016-01-01

    This research paper presents an initial attempt to introduce and explain the emergence of new phenomenon, which we refer to as platform constellations. Functioning as highly modular systems, the platform constellations are collections of highly connected platforms which co-exist in parallel...... and as such allow us to study platforms not only as separate entities, but also to investigate the relationship between several platforms offered and governed by one and the same platform provider. By investigating two case studies of indigenous platform constellations formed around the hugely popular instant...... messaging apps KakaoTalk and LINE, we are able to gain valuable insights about the nature of these new constructions and to capture and synthesize their main characteristics in a framework. Our results show that platform constellations possess unique innovative capabilities, which can improve users...

  9. Can an Internal Locus of Control and Social Support Reduce Work-Related Levels of Stress and Strain?: A Comparative Study Between Spanish Owners and Managers.

    Science.gov (United States)

    Ariza-Montes, Antonio; Leal-Rodríguez, Antonio L; Rodríguez-Félix, Lucía; Albort-Morant, Gema

    2017-09-01

    The aim of this article is to assess the role played by both individual and contextual factors in reducing the manager's levels of stress and strain within the workplace setting. This article also highlights the manager's locus of control (LOC) as an internal factor and emphasizes the social support variable as a contextual factor. We use a sample of 332 respondents belonging to Spanish manufacturing and services firms and a structural equation modeling technique (partial least squares path modeling). The results reveal that there are significant differences between managers and owners about stress-strain relationship. The study provides support for the literature on stress management, which emphasizes the importance of a LOC and social support in influencing stress and strain between managers and owners.

  10. A highly selective and sensitive cocaine aptasensor based on covalent attachment of the aptamer-functionalized AuNPs onto nanocomposite as the support platform

    Energy Technology Data Exchange (ETDEWEB)

    Roushani, Mahmoud, E-mail: mahmoudroushani@yahoo.com; Shahdost-fard, Faezeh

    2015-01-01

    Highlights: • Functionalized thiol-terminated cocaine aptamer was functionalized with AuNPs. • MWCNTs/IL/Chit was employed for covalent attachment of Apt-capture probe onto electrode. • (K{sub 3}Fe(CN){sub 6}) was used as the redox probe and DPV as analytical technique. • The aptasensor showed high sensitivity and selectivity. • Linear range from 1 nM to 11,000 nM with LOD of 100 pM for cocaine detection was obtained. - Abstract: Based on the conformational changes of the aptamer-functionalized gold nanoparticles (AuNPs) onto MWCNTs/IL/Chit nanocomposite as the support platform, we have developed a sensitive and selective electrochemical aptasensor for the detection of cocaine. The 5′-amine-3′-AuNP terminated aptamer is covalently attached to a MWCNTs/IL/Chit nanocomposite. The interaction of cocaine with the aptamer functionalized AuNP caused the aptamer to be folded and the AuNPs with negative charge at the end of the aptamer came to the near of electrode surface therefore, the electron transfer between ferricyanide (K{sub 3}Fe(CN){sub 6}) as redox probe and electrode surface was inhibited. A decreased current of (K{sub 3}Fe(CN){sub 6}) was monitored by differential pulse voltammetry technique. In an optimized condition the calibration curve for cocaine concentration was linear up to 11 μM with detection limit (signal-to-noise ratio of 3) of 100 pM. To test the selectivity of the prepared aptasensor sensing platform applicability, some analgesic drugs as the interferes were examined. The potential of the aptasensor was successfully applied for measuring cocaine concentration in human blood serum. Based on our experiments it can be said that the present method is absolutely beneficial in developing other electrochemical aptasensor.

  11. Micro-electromechanical Systems for Probing Novel Strain Physics and Innovative Strain Devices in 2D Materials

    Science.gov (United States)

    Christopher, Jason; Vutukuru, Mounika; Bishop, David; Swan, Anna; Goldberg, Bennett

    Straining 2D materials can dramatically change electrical, thermal and optical properties and can even cause unconventional behavior such as generating pseudo-magnetic fields. However attempts at probing these effects have been hindered by the difficulty involved with precisely straining these materials. Here we present micro-electromechanical systems (MEMS) as an ideal platform for straining 2D materials because they are readily compatible with existing electronics and their size makes them compatible with 2D materials. Additionally the MEMS platform does more than facilitate experimentation; by freeing us to think of strain as dynamical it makes a whole new class of devices practical for next generation technology. To demonstrate the power of this platform we have for the first time measured the strain response of the Raman and photoluminescence spectra of suspended MoS2, and measured the friction force between MoS2 and the MEMS structure. This talk will touch on the basics of designing MEMS structures for straining 2D materials, how to transfer 2D materials onto MEMS without break either, proof of concept experimental results, and next steps in developing the MEMS platform. This work is supported by NSF DMR Grant 1411008, and author J. Christopher thanks the NDSEG program for its support.

  12. Payment Platform

    DEFF Research Database (Denmark)

    Hjelholt, Morten; Damsgaard, Jan

    2012-01-01

    Payment transactions through the use of physical coins, bank notes or credit cards have for centuries been the standard formats of exchanging money. Recently online and mobile digital payment platforms has entered the stage as contenders to this position and possibly could penetrate societies...... thoroughly and substitute current payment standards in the decades to come. This paper portrays how digital payment platforms evolve in socio-technical niches and how various technological platforms aim for institutional attention in their attempt to challenge earlier platforms and standards. The paper...... applies a co-evolutionary multilevel perspective to model the interplay and processes between technology and society wherein digital payment platforms potentially will substitute other payment platforms just like the credit card negated the check. On this basis this paper formulate a multilevel conceptual...

  13. Psychological job strain, social support at work and daytime secretion of dehydroepiandrosterone (DHEA) in healthy female employees: cross-sectional analyses.

    Science.gov (United States)

    Ota, Atsuhiko; Yatsuya, Hiroshi; Mase, Junji; Ono, Yuichiro

    2015-11-10

    Evidence is limited concerning the influences of high psychological job strain and low social support at work on daytime secretion of dehydroepiandrosterone (DHEA), which demonstrates anti-cortisol effects. We carried out a cross-sectional study to examine the associations of job strain and social support with daytime secretion amounts of DHEA and cortisol and daytime variation of the cortisol-to-DHEA ratio (C/D ratio) in healthy female workers. Study subjects comprised 115 healthy female nursery school teachers. Area under the curve with respect to ground (AUCG) of salivary DHEA, cortisol and C/D ratio was calculated for estimation of daytime secretion and variation. Social support scores were negatively associated with daytime DHEA secretion (standardized partial regression coefficient = -0.343, P DHEA, cortisol or the C/D ratio. In summary, we found that daytime DHEA secretion was increased in healthy workers with low social support, perhaps independent of daytime cortisol secretion.

  14. SAYSOY- Space Apparatus to Yield SOY sprouts: Growing sprouts in a growth support system for experiments on unmanned platforms in space

    Science.gov (United States)

    De Micco, Veronica; Aronne, Giovanna; Scala, Michele; Eduardo, Pasquale; Haladich, Marco; Castagnolo, Dario; Fortezza, Raimondo

    2005-08-01

    The aim of this study was to design and develop an automatic growth support system for sprouts production in Space addressing a main biological requirement: seedling development had to occur completely under microgravity conditions from seed imbibition until chemical fixation of seedlings. This research is placed within the scenario of producing sprouts of soy, and other species, on board of Space platforms to integrate astronauts' diet with fresh food.The project SAYSOY was submitted within the Education programmes of ESA and was selected for the flight onboard of FOTON M2 satellite. The experiment is based on previous tests conducted on ground in simulated low-gravity conditions where emphasis was addressed to the effect of altered gravity on biological processes that affect nutritional value (metabolism of phenolics) and taste satisfaction (hydration of tissues, vascular differentiation and lignification affecting turgidity and softness of sprouts). The hardware was developed according to the specifications of the FOTON capsule and biological requirements in the sight of the planned analyses of biometrical anatomy on the recovered seedlings. The experiment SAYSOY was successfully conducted flying from May 31st to June 16th, 2005.

  15. Qt/Embedded Transplant Supporting Touch Screen on the Linux Platform%Linux平台下支持触摸屏的Qt/Embedded移植

    Institute of Scientific and Technical Information of China (English)

    张敏; 张井岗

    2011-01-01

    随着嵌入式的发展,触摸屏以友善的人机交互性、操作简单灵活、输入速度快,已逐渐取代键盘,成为嵌入式系统的主流输入设备;而Qt作为跨平台的图形用户界面工具包诞生以后,已经扩展到了包括便携式设备在内的几乎当今程序设计的所有领域.以S3C2416为例,介绍了在Linux平台下支持触摸屏的Qt/Embedded移植的详细过程,包括系统环境介绍、带触摸屏库的Qt/Embedded的编译、Linux文件系统设置等,并挑选了一个demo程序对移植情况进行了检验.最后对支持触摸屏的嵌入式系统作了初步展望.%Along with the fast development of embedded system, touch screen has gradually replaced the keyboard and becomes the main input device in embedded systems. QT invented as a cross-platform GUI (graphical user interface) toolkit has extended to many fields of program design including portable devices. In this paper S3C2416 is exemplified to introduce the process of Qt / Embedded transplant supporting touch screen, which includes the system environment introduction, Qt / Embedded compiler with touch screen library, file system settings and so on. Then a demo program is selected to test the transplant. At last an outlook is made for the embedded system supporting touch screen.

  16. Strain-driven and ultrasensitive resistive sensor/switch based on conductive alginate/nitrogen-doped carbon-nanotube-supported Ag hybrid aerogels with pyramid design.

    Science.gov (United States)

    Zhao, Songfang; Zhang, Guoping; Gao, Yongju; Deng, Libo; Li, Jinhui; Sun, Rong; Wong, Ching-Ping

    2014-12-24

    Flexible strain-driven sensor is an essential component in the flexible electronics. Especially, high durability and sensitivity to strain are required. Here, we present an efficient and low-cost fabrication strategy to construct a highly sensitive and flexible pressure sensor based on a conductive, elastic aerogel with pyramid design. When pressure is loaded, the contact area between the interfaces of the conductive aerogel and the copper electrode as well as among the building blocks of the nitrogen-doped carbon-nanotube-supported Ag (N-CNTs/Ag) aerogel monoliths, changes in reversible and directional manners. This contact resistance mechanism enables the hybrid aerogels to act as strain-driven sensors with high sensitivity and excellent on/off swithching behavior, and the gauge factor (GF) is ∼15 under strain of 3%, which is superior to those reported for other aerogels. In addition, robust, elastomeric and conductive nanocomposites can be fabricated by injecting polydimethylsiloxane (PDMS) into alginate/N-CNTs/Ag aerogels. Importantly, the building blocks forming the aerogels retain their initial contact and percolation after undergoing large-strain deformation, PDMS infiltration, and cross-linking of PDMS, suggesting their potential applications as strain sensors.

  17. Flexible experimental FPGA based platform

    DEFF Research Database (Denmark)

    Andersen, Karsten Holm; Nymand, Morten

    2016-01-01

    This paper presents an experimental flexible Field Programmable Gate Array (FPGA) based platform for testing and verifying digital controlled dc-dc converters. The platform supports different types of control strategies, dc-dc converter topologies and switching frequencies. The controller platform...... interface supporting configuration and reading of setup parameters, controller status and the acquisition memory in a simple way. The FPGA based platform, provides an easy way within education or research to use different digital control strategies and different converter topologies controlled by an FPGA...

  18. Numerical Prediction of Experimentally Observed Behavior of a Scale Model of an Offshore Wind Turbine Supported by a Tension-Leg Platform: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Prowell, I.; Robertson, A.; Jonkman, J.; Stewart, G. M.; Goupee, A. J.

    2013-01-01

    Realizing the critical importance the role physical experimental tests play in understanding the dynamics of floating offshore wind turbines, the DeepCwind consortium conducted a one-fiftieth-scale model test program where several floating wind platforms were subjected to a variety of wind and wave loading condition at the Maritime Research Institute Netherlands wave basin. This paper describes the observed behavior of a tension-leg platform, one of three platforms tested, and the systematic effort to predict the measured response with the FAST simulation tool using a model primarily based on consensus geometric and mass properties of the test specimen.

  19. Modul.LES: a multi-compartment, multi-organism aquatic life support system as experimental platform for research in ∆g

    Science.gov (United States)

    Hilbig, Reinhard; Anken, Ralf; Grimm, Dennis

    In view of space exploration and long-term satellite missions, a new generation of multi-modular, multi-organism bioregenerative life support system with different experimental units (Modul.LES) is planned, and subunits are under construction. Modul.LES will be managed via telemetry and remote control and therefore is a fully automated experimental platform for different kinds of investigations. After several forerunner projects like AquaCells (2005), C.E.B.A.S. (1998, 2003) or Aquahab (OHB-System AG the Oreochromis Mossambicus Eu-glena Gracilis Aquatic Habitat (OmegaHab) was successfully flown in 2007 in course of the FOTON-M3 Mission. It was a 3 chamber controlled life support system (CLSS), compris-ing a bioreactor with the green algae Euglena gracilis, a fish chamber with larval cichlid fish Oreochromis mossambicus and a filter chamber with biodegrading bacteria. The sensory super-vision of housekeeping management was registered and controlled by telemetry. Additionally, all scientific data and videos of the organisms aboard were stored and sequentially transmitted to relay stations. Based on the effective performance of OmegaHab, this system was chosen for a reflight on Bion-M1 in 2012. As Bion-M1 is a long term mission (appr. 4 weeks), this CLSS (OmegaHab-XP) has to be redesigned and refurbished with enhanced performance. The number of chambers has been increased from 3 to 4: an algae bioreactor, a fish tank for adult and larval fish (hatchery inserted), a nutrition chamber with higher plants and crustaceans and a filter chamber. The OmegaHab-XP is a full automated system with an extended satellite downlink for video monitoring and housekeeping data acquisition, but no uplink for remote control. OmegaHab-XP provides numerous physical and chemical parameters which will be monitored regarding the state of the biological processes and thus enables the automated con-trol aboard. Besides the two basic parameters oxygen content and temperature, products of the

  20. Human prostate supports more efficient replication of HIV-1 R5 than X4 strains ex vivo

    Directory of Open Access Journals (Sweden)

    Denis Hélène

    2008-12-01

    Full Text Available Abstract Background In order to determine whether human prostate can be productively infected by HIV-1 strains with different tropism, and thus represent a potential source of HIV in semen, an organotypic culture of prostate from men undergoing prostatic adenomectomy for benign prostate hypertrophy (BPH was developed. The presence of potential HIV target cells in prostate tissues was investigated using immunohistochemistry. The infection of prostate explants following exposures with HIV-1 R5, R5X4 and X4 strains was analyzed through the measure of RT activity in culture supernatants, the quantification of HIV DNA in the explants and the detection of HIV RNA+ cells in situ. Results The overall prostate characteristics were retained for 21/2 weeks in culture. Numerous potential HIV-1 target cells were detected in the prostate stroma. Whilst HIV-1 R5SF162 strain consistently productively infected prostatic T lymphocytes and macrophages, the prototypic X4IIIB strain and a primary R5X4 strain showed less efficient replication in this organ. Conclusion The BPH prostate is a site of HIV-1 R5 replication that could contribute virus to semen. A limited spreading of HIV-1 X4 and R5X4 in this organ could participate to the preferential sexual transmission of HIV-1 R5 strains.

  1. Research on the supporting platform of teaching practice of logistics information management in colleges and universities%高校物流信息管理实践教学支撑平台研究

    Institute of Scientific and Technical Information of China (English)

    段一群

    2013-01-01

    面向物流信息化提出构建跨专业、校企合作的高校物流信息管理实践教学支撑平台,探讨了平台建设思路、基本架构、师资建设、运行机制和平台的实战型项目化物流实践教学新模式。%For logistics informationization to construct interdisciplinary, school-enterprise cooperation in supporting platform of teaching practice of logistics information management, discusses the new teaching mode of logistics practical project of platform construction ideas, basic construction, teachers construction, operation mechanism and platform.

  2. Current meter - direction and other data from FIXED PLATFORMS in support of the Brine Disposal project from 01 August 1978 to 31 August 1978 (NODC Accession 7900073)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Current meter - direction and other data were collected from FIXED PLATFORMS from 01 August 1978 to 31 August 1978. Data were collected by the National Data Buoy...

  3. Wave spectra, meteorological, and other data from FIXED PLATFORMS in support of the Santa Barbara Channel project from 13 March 1984 (NODC Accession 8500085)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Wave spectra, meteorological, and other data were collected from FIXED PLATFORMS from 13 March 1984. Data were collected by the Science Applications, Inc. - Raleigh...

  4. Current meter - direction and other data from FIXED PLATFORMS in support of the Brine Disposal project from 01 September 1978 to 30 September 1978 (NODC Accession 7900007)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Current meter - direction and other data were collected from FIXED PLATFORMS from 01 September 1978 to 30 September 1978. Data were collected by the National Data...

  5. Current meter - direction and other data from FIXED PLATFORMS in support of the Brine Disposal project from 01 October 1979 to 01 January 1980 (NODC Accession 8000049)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Current meter - direction and other data were collected from FIXED PLATFORMS from 01 October 1979 to 01 January 1980. Data were collected by the National Data Buoy...

  6. Current meter components and other data from FIXED PLATFORMS in support of the Physical Oceanography Field Program Offshore North Carolina from 19 February 1992 (NODC Accession 9400063)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Current meter components data were collected from FIXED PLATFORMS in the NW Atlantic (limit-40 W) from 19 February 1992. Data were collected by the Science...

  7. [Lens platform].

    Science.gov (United States)

    Łukaszewska-Smyk, Agnieszka; Kałuzny, Józef

    2010-01-01

    The lens platform defines lens structure and lens material. Evolution of lens comprises change in their shape, angulation of haptens and transition of three-piece lens into one-piece lens. The lens fall into two categories: rigid (PMMA) and soft (siliconic, acrylic, colameric). The main lens maaterials are polymers (hydrophilic and hydrophobic). The lens platform has an effect on biocompatibility, bioadhesion, stability of lens in capsule, degree of PCO evolution and sensitiveness to laser damages.

  8. Platform contents

    OpenAIRE

    Renault, Régis

    2014-01-01

    A monopoly platform hosts advertisers who compete on a market for horizontally differentiated products. These products may be either mass market products that appeal broadly to the entire consumer population or niche products that are tailored to the tastes of some particular group. Consumers search sequentially through ads incurring a surfing cost of moving to the next ad. They may click on an ad at some cost, which provides all relevant information and the opportunity to buy. The platform c...

  9. A Typology of Multi-sided Platforms

    DEFF Research Database (Denmark)

    Staykova, Kalina Stefanova; Damsgaard, Jan

    2015-01-01

    exemplary cases which allow us to illustrate the platform heterogeneity and to support new MSPs typology. As examples we include a physical two-sided platform (Gatwick Airport) that adds a third side, a digital one-sided platform transformed into being two-sided (Pingit) and a digital one-sided platform......In this paper we address how the composition of a platform impacts the platform’s business model. By platform’s business model we mean platform features, platform architecture and platform governance. To this end, we construct the Platform Business Model Framework. We apply the framework to three...... in several configurations. The particular platform architecture can explain the difficulties in designing a viable business models for platforms....

  10. Joint Applications Pilot of the National Climate Predictions and Projections Platform and the North Central Climate Science Center: Delivering climate projections on regional scales to support adaptation planning

    Science.gov (United States)

    Ray, A. J.; Ojima, D. S.; Morisette, J. T.

    2012-12-01

    The DOI North Central Climate Science Center (NC CSC) and the NOAA/NCAR National Climate Predictions and Projections (NCPP) Platform and have initiated a joint pilot study to collaboratively explore the "best available climate information" to support key land management questions and how to provide this information. NCPP's mission is to support state of the art approaches to develop and deliver comprehensive regional climate information and facilitate its use in decision making and adaptation planning. This presentation will describe the evolving joint pilot as a tangible, real-world demonstration of linkages between climate science, ecosystem science and resource management. Our joint pilot is developing a deliberate, ongoing interaction to prototype how NCPP will work with CSCs to develop and deliver needed climate information products, including translational information to support climate data understanding and use. This pilot also will build capacity in the North Central CSC by working with NCPP to use climate information used as input to ecological modeling. We will discuss lessons to date on developing and delivering needed climate information products based on this strategic partnership. Four projects have been funded to collaborate to incorporate climate information as part of an ecological modeling project, which in turn will address key DOI stakeholder priorities in the region: Riparian Corridors: Projecting climate change effects on cottonwood and willow seed dispersal phenology, flood timing, and seedling recruitment in western riparian forests. Sage Grouse & Habitats: Integrating climate and biological data into land management decision models to assess species and habitat vulnerability Grasslands & Forests: Projecting future effects of land management, natural disturbance, and CO2 on woody encroachment in the Northern Great Plains The value of climate information: Supporting management decisions in the Plains and Prairie Potholes LCC. NCCSC's role in

  11. The psychological well-being of disability caregivers: examining the roles of family strain, family-to-work conflict, and perceived supervisor support.

    Science.gov (United States)

    Li, Andrew; Shaffer, Jonathan; Bagger, Jessica

    2015-01-01

    We draw on the cross-domain model of work-family conflict and conservation of resources theory to examine the relationship between disability caregiving demands and the psychological well-being of employed caregivers. Using a sample of employed disability caregivers from a national survey, we found that the relationship between caregiving demands and family-to-work conflict was stronger when employees experienced high levels of strain from family. Additionally, we found high levels of family to-work conflict were subsequently associated with decreases in life satisfaction and increases in depression, but only when perceived supervisor support was low. Overall, our findings suggest an indirect relationship between caregiving demands and psychological well-being that is mediated by family-to-work conflict and is conditional on family strain and perceived supervisor support. The theoretical and practical implications of these findings are discussed.

  12. Hardware Design and Implementation of the Master Control System of Antarctic Support Platform%南极科考支撑平台主控系统的硬件设计与实现

    Institute of Scientific and Technical Information of China (English)

    谢蔚卿; 葛健; 方仕雄; 朱蔚萍; 张侃健; 魏海坤

    2012-01-01

    Hie Antarctic support platform is the first energy support platform that is developed independently by China.The Master Control System of the platform was planned based on the foreign similar platform.Considering the special natural environment, Rockwell redundancy controller and redundancy ControlNet were designed to enhance reliability.The equipment selection and structure design of Master Control System was focused.The field running shows that the system meets the design requirement.%南极科考支撑平台是我国首座独立自主研发的极端条件下科考支撑平台,主控系统是平台的现场控制中枢.在国外同类平台研制的基础上,针对平台所处的特殊自然环境,从增强系统的可靠性出发,采用了冗余控制器和冗余通信网络方式.着重介绍了主控系统的设备选型及结构设计.平台现场运行表明,平台主控系统硬件选型正确可靠,设计完全可行.

  13. Towards a Scalable and Adaptive Application Support Platform for Large-Scale Distributed E-Sciences in High-Performance Network Environments

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Chase Qishi [New Jersey Inst. of Technology, Newark, NJ (United States); Univ. of Memphis, TN (United States); Zhu, Michelle Mengxia [Southern Illinois Univ., Carbondale, IL (United States)

    2016-06-06

    The advent of large-scale collaborative scientific applications has demonstrated the potential for broad scientific communities to pool globally distributed resources to produce unprecedented data acquisition, movement, and analysis. System resources including supercomputers, data repositories, computing facilities, network infrastructures, storage systems, and display devices have been increasingly deployed at national laboratories and academic institutes. These resources are typically shared by large communities of users over Internet or dedicated networks and hence exhibit an inherent dynamic nature in their availability, accessibility, capacity, and stability. Scientific applications using either experimental facilities or computation-based simulations with various physical, chemical, climatic, and biological models feature diverse scientific workflows as simple as linear pipelines or as complex as a directed acyclic graphs, which must be executed and supported over wide-area networks with massively distributed resources. Application users oftentimes need to manually configure their computing tasks over networks in an ad hoc manner, hence significantly limiting the productivity of scientists and constraining the utilization of resources. The success of these large-scale distributed applications requires a highly adaptive and massively scalable workflow platform that provides automated and optimized computing and networking services. This project is to design and develop a generic Scientific Workflow Automation and Management Platform (SWAMP), which contains a web-based user interface specially tailored for a target application, a set of user libraries, and several easy-to-use computing and networking toolkits for application scientists to conveniently assemble, execute, monitor, and control complex computing workflows in heterogeneous high-performance network environments. SWAMP will enable the automation and management of the entire process of scientific

  14. Towards a Scalable and Adaptive Application Support Platform for Large-Scale Distributed E-Sciences in High-Performance Network Environments

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Chase Qishi [New Jersey Inst. of Technology, Newark, NJ (United States); Univ. of Memphis, TN (United States); Zhu, Michelle Mengxia [Southern Illinois Univ., Carbondale, IL (United States)

    2016-06-06

    The advent of large-scale collaborative scientific applications has demonstrated the potential for broad scientific communities to pool globally distributed resources to produce unprecedented data acquisition, movement, and analysis. System resources including supercomputers, data repositories, computing facilities, network infrastructures, storage systems, and display devices have been increasingly deployed at national laboratories and academic institutes. These resources are typically shared by large communities of users over Internet or dedicated networks and hence exhibit an inherent dynamic nature in their availability, accessibility, capacity, and stability. Scientific applications using either experimental facilities or computation-based simulations with various physical, chemical, climatic, and biological models feature diverse scientific workflows as simple as linear pipelines or as complex as a directed acyclic graphs, which must be executed and supported over wide-area networks with massively distributed resources. Application users oftentimes need to manually configure their computing tasks over networks in an ad hoc manner, hence significantly limiting the productivity of scientists and constraining the utilization of resources. The success of these large-scale distributed applications requires a highly adaptive and massively scalable workflow platform that provides automated and optimized computing and networking services. This project is to design and develop a generic Scientific Workflow Automation and Management Platform (SWAMP), which contains a web-based user interface specially tailored for a target application, a set of user libraries, and several easy-to-use computing and networking toolkits for application scientists to conveniently assemble, execute, monitor, and control complex computing workflows in heterogeneous high-performance network environments. SWAMP will enable the automation and management of the entire process of scientific

  15. ITS Platform

    DEFF Research Database (Denmark)

    Tøfting, Svend; Lahrmann, Harry; Agerholm, Niels

    2014-01-01

    Aalborg University and two local companies have over the past four years developed and tested an ITS Platform, which can be used for communication with cars and for providing a number of services to the drivers. The purpose has been to perform a technological test of the possible use of a hidden ...... not have to be very intelligent. This is gradually taken over by applications on smart phones. The ITS Platform with 425 test drivers is now completely developed and can be used for technological testing of e.g. payment systems.......Aalborg University and two local companies have over the past four years developed and tested an ITS Platform, which can be used for communication with cars and for providing a number of services to the drivers. The purpose has been to perform a technological test of the possible use of a hidden...

  16. Antibacterial activity of essential oils, their blends and mixtures of their main constituents against some strains supporting livestock mastitis.

    Science.gov (United States)

    Fratini, Filippo; Casella, Sergio; Leonardi, Michele; Pisseri, Francesca; Ebani, Valentina Virginia; Pistelli, Laura; Pistelli, Luisa

    2014-07-01

    Ten of the most known and used commercial essential oils (Cinnamomum zeylanicum L., Citrus bergamia Risso, Eucalyptus globulus Labill., Foeniculum vulgare Mill., Origanum majorana L., Origanum vulgare L., Rosmarinus officinalis L., Satureja montana L., Thymus vulgaris L. ct. carvacrol, Thymus vulgaris L. ct. thymol) were tested against six bacteria strains Staphylococcus aureus, Staphylococcus chromogenes, Staphylococcus sciuri, Staphylococcus warneri, Staphylococcus xylosus and Escherichia coli, responsible for mastitis in animals. The best results were achieved by S. montana, T. vulgaris ct. thymol and O. vulgare. Two binary mixtures of essential oils (EOs) were prepared of S. montana and T. vulgaris ct. thymol (ST) and of S. montana and O. vulgare (SO). The ST mixture exhibited the best inhibitory activity against all the tested bacterial strains. Two artificial mixtures of carvacrol/thymol (AB) and carvacrol/thymol/p-cymene (CD) were prepared and tested against all of the bacterial strains used. The results exhibited a general reduction of the inhibitory activity of mixture AB, although not reaching the inhibition of the ST and SO mixtures. However the mixture CD presented an apparent strong inhibition against S. aureus and S. sciuri. The EO mixtures and the mixture CD represent promising phytotherapic approaches against bacteria strains responsible for environmental mastitis.

  17. BIOREGIS software platform based on GIS technology to support in-situ remediation of petroleum contaminated sites. Case study: razvad - dambovita county, Romania

    Energy Technology Data Exchange (ETDEWEB)

    Anicai, Ovidiu [Institute for Computers - ITC SA, Bucharest (Romania); Anicai, Liana [PSV COMPANY SA, Direction of Research, Bucharest (Romania)

    2011-12-15

    With a need for the management of petroleum contaminated sites on Romanian territory, an experimental software platform involving ESRI-ArcGIS technologies (BIOREGIS) is presented in this study. The BIOREGIS platform is aimed to: (i) Build the structure of relational, standardized databases to store spatial and textual characteristic information on polluted sites for further risk analysis and planning of remediation actions, (ii) improve the pollution risk assessment methodology for Romanian petroleum contaminated sites and its informatics implementation, and (iii) develop and operate the software platform for pollution risk based management involving GIS/remote sensing technologies and remediation activities. The operation of BIOREGIS has been tested for a pilot contaminated area situated at Razvad - Dambovita County, which has been subjected to in situ remediation procedures involving both bioremediation and electrokinetic processes. (Copyright copyright 2011 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  18. ITS Platform

    DEFF Research Database (Denmark)

    Tøfting, Svend; Lahrmann, Harry; Agerholm, Niels

    2014-01-01

    Aalborg University and two local companies have over the past four years developed and tested an ITS Platform, which can be used for communication with cars and for providing a number of services to the drivers. The purpose has been to perform a technological test of the possible use of a hidden ...... not have to be very intelligent. This is gradually taken over by applications on smart phones. The ITS Platform with 425 test drivers is now completely developed and can be used for technological testing of e.g. payment systems....

  19. Power Quality Indices Estimation Platform

    Directory of Open Access Journals (Sweden)

    Eliana I. Arango-Zuluaga

    2013-11-01

    Full Text Available An interactive platform for estimating the quality indices in single phase electric power systems is presented. It meets the IEEE 1459-2010 standard recommendations. The platform was developed in order to support teaching and research activities in electric power quality. The platform estimates the power quality indices from voltage and current signals using three different algorithms based on fast Fourier transform (FFT, wavelet packet transform (WPT and least squares method. The results show that the algorithms implemented are efficient for estimating the quality indices of the power and the platform can be used according to the objectives established. 

  20. Platform computing

    CERN Multimedia

    2002-01-01

    "Platform Computing releases first grid-enabled workload management solution for IBM eServer Intel and UNIX high performance computing clusters. This Out-of-the-box solution maximizes the performance and capability of applications on IBM HPC clusters" (1/2 page) .

  1. A mouse informatics platform for phenotypic and translational discovery.

    Science.gov (United States)

    Ring, Natalie; Meehan, Terrence F; Blake, Andrew; Brown, James; Chen, Chao-Kung; Conte, Nathalie; Di Fenza, Armida; Fiegel, Tanja; Horner, Neil; Jacobsen, Julius O B; Karp, Natasha; Lawson, Thomas; Mason, Jeremy C; Matthews, Peter; Morgan, Hugh; Relac, Mike; Santos, Luis; Smedley, Damian; Sneddon, Duncan; Pengelly, Alice; Tudose, Ilinca; Warren, Jonathan W G; Westerberg, Henrik; Yaikhom, Gagarine; Parkinson, Helen; Mallon, Ann-Marie

    2015-10-01

    The International Mouse Phenotyping Consortium (IMPC) is providing the world's first functional catalogue of a mammalian genome by characterising a knockout mouse strain for every gene. A robust and highly structured informatics platform has been developed to systematically collate, analyse and disseminate the data produced by the IMPC. As the first phase of the project, in which 5000 new knockout strains are being broadly phenotyped, nears completion, the informatics platform is extending and adapting to support the increasing volume and complexity of the data produced as well as addressing a large volume of users and emerging user groups. An intuitive interface helps researchers explore IMPC data by giving overviews and the ability to find and visualise data that support a phenotype assertion. Dedicated disease pages allow researchers to find new mouse models of human diseases, and novel viewers provide high-resolution images of embryonic and adult dysmorphologies. With each monthly release, the informatics platform will continue to evolve to support the increased data volume and to maintain its position as the primary route of access to IMPC data and as an invaluable resource for clinical and non-clinical researchers.

  2. Earth Observation-Supported Service Platform for the Development and Provision of Thematic Information on the Built Environment - the Tep-Urban Project

    Science.gov (United States)

    Esch, T.; Asamer, H.; Boettcher, M.; Brito, F.; Hirner, A.; Marconcini, M.; Mathot, E.; Metz, A.; Permana, H.; Soukop, T.; Stanek, F.; Kuchar, S.; Zeidler, J.; Balhar, J.

    2016-06-01

    The Sentinel fleet will provide a so-far unique coverage with Earth observation data and therewith new opportunities for the implementation of methodologies to generate innovative geo-information products and services. It is here where the TEP Urban project is supposed to initiate a step change by providing an open and participatory platform based on modern ICT technologies and services that enables any interested user to easily exploit Earth observation data pools, in particular those of the Sentinel missions, and derive thematic information on the status and development of the built environment from these data. Key component of TEP Urban project is the implementation of a web-based platform employing distributed high-level computing infrastructures and providing key functionalities for i) high-performance access to satellite imagery and derived thematic data, ii) modular and generic state-of-the art pre-processing, analysis, and visualization techniques, iii) customized development and dissemination of algorithms, products and services, and iv) networking and communication. This contribution introduces the main facts about the TEP Urban project, including a description of the general objectives, the platform systems design and functionalities, and the preliminary portfolio products and services available at the TEP Urban platform.

  3. Front-end conceptual platform modeling

    DEFF Research Database (Denmark)

    Guðlaugsson, Tómas Vignir; Ravn, Poul Martin; Mortensen, Niels Henrik

    2014-01-01

    Platform thinking has been the subject of investigation and deployment in many projects in both academia and industry. Most contributions involve the restructuring of product programs, and only a few support front-end development of a new platform in parallel with technology development....... This contribution deals with the development of product platforms in front-end projects and introduces a modeling tool: the Conceptual Product Platform model. State of the art within platform modeling forms the base of a modeling formalism for a Conceptual Product Platform model. The modeling formalism is explored...... through an example and applied in a case in which the Conceptual Product Platform model has supported the front-end development of a platform for an electro-active polymer technology. The case describes the contents of the model and how its application supported the development work in the project...

  4. The NCI High Performance Computing (HPC) and High Performance Data (HPD) Platform to Support the Analysis of Petascale Environmental Data Collections

    Science.gov (United States)

    Evans, B. J. K.; Pugh, T.; Wyborn, L. A.; Porter, D.; Allen, C.; Smillie, J.; Antony, J.; Trenham, C.; Evans, B. J.; Beckett, D.; Erwin, T.; King, E.; Hodge, J.; Woodcock, R.; Fraser, R.; Lescinsky, D. T.

    2014-12-01

    The National Computational Infrastructure (NCI) has co-located a priority set of national data assets within a HPC research platform. This powerful in-situ computational platform has been created to help serve and analyse the massive amounts of data across the spectrum of environmental collections - in particular the climate, observational data and geoscientific domains. This paper examines the infrastructure, innovation and opportunity for this significant research platform. NCI currently manages nationally significant data collections (10+ PB) categorised as 1) earth system sciences, climate and weather model data assets and products, 2) earth and marine observations and products, 3) geosciences, 4) terrestrial ecosystem, 5) water management and hydrology, and 6) astronomy, social science and biosciences. The data is largely sourced from the NCI partners (who include the custodians of many of the national scientific records), major research communities, and collaborating overseas organisations. By co-locating these large valuable data assets, new opportunities have arisen by harmonising the data collections, making a powerful transdisciplinary research platformThe data is accessible within an integrated HPC-HPD environment - a 1.2 PFlop supercomputer (Raijin), a HPC class 3000 core OpenStack cloud system and several highly connected large scale and high-bandwidth Lustre filesystems. New scientific software, cloud-scale techniques, server-side visualisation and data services have been harnessed and integrated into the platform, so that analysis is performed seamlessly across the traditional boundaries of the underlying data domains. Characterisation of the techniques along with performance profiling ensures scalability of each software component, all of which can either be enhanced or replaced through future improvements. A Development-to-Operations (DevOps) framework has also been implemented to manage the scale of the software complexity alone. This ensures that

  5. Identification of platform levels

    DEFF Research Database (Denmark)

    Mortensen, Niels Henrik

    2005-01-01

    reduction, ability to launch a wider product portfolio without increasing resources and reduction of complexity within the whole company. To support the multiple product development process, platform based product development has in many companies such as Philips, VW, Ford etc. proven to be a very effective...... because the nature of developing platforms and applications are very different. In single product development reuse is often determined by individual designers, in multiple product development reuse is to a large degree a management issue. It is difficult for a company to switch from single to multiple...... development will be examined. Based on the identification of the above characteristics five platform levels are described. The research presented in this paper is a result of MSc, Ph.D projects at the Technical University of Denmark and consultancy projects within the organisation of Institute of Product...

  6. Universal visualization platform

    Science.gov (United States)

    Gee, Alexander G.; Li, Hongli; Yu, Min; Smrtic, Mary Beth; Cvek, Urska; Goodell, Howie; Gupta, Vivek; Lawrence, Christine; Zhou, Jainping; Chiang, Chih-Hung; Grinstein, Georges G.

    2005-03-01

    Although there are a number of visualization systems to choose from when analyzing data, only a few of these allow for the integration of other visualization and analysis techniques. There are even fewer visualization toolkits and frameworks from which one can develop ones own visualization applications. Even within the research community, scientists either use what they can from the available tools or start from scratch to define a program in which they are able to develop new or modified visualization techniques and analysis algorithms. Presented here is a new general-purpose platform for constructing numerous visualization and analysis applications. The focus of this system is the design and experimentation of new techniques, and where the sharing of and integration with other tools becomes second nature. Moreover, this platform supports multiple large data sets, and the recording and visualizing of user sessions. Here we introduce the Universal Visualization Platform (UVP) as a modern data visualization and analysis system.

  7. Transactional Network Platform: Applications

    Energy Technology Data Exchange (ETDEWEB)

    Katipamula, Srinivas; Lutes, Robert G.; Ngo, Hung; Underhill, Ronald M.

    2013-10-31

    In FY13, Pacific Northwest National Laboratory (PNNL) with funding from the Department of Energy’s (DOE’s) Building Technologies Office (BTO) designed, prototyped and tested a transactional network platform to support energy, operational and financial transactions between any networked entities (equipment, organizations, buildings, grid, etc.). Initially, in FY13, the concept demonstrated transactions between packaged rooftop air conditioners and heat pump units (RTUs) and the electric grid using applications or "agents" that reside on the platform, on the equipment, on a local building controller or in the Cloud. The transactional network project is a multi-lab effort with Oakridge National Laboratory (ORNL) and Lawrence Berkeley National Laboratory (LBNL) also contributing to the effort. PNNL coordinated the project and also was responsible for the development of the transactional network (TN) platform and three different applications associated with RTUs. This document describes two applications or "agents" in details, and also summarizes the platform. The TN platform details are described in another companion document.

  8. The moderating effects of work-based and non-work based support on the relation between job insecurity and subsequent strain

    Directory of Open Access Journals (Sweden)

    K Näswall

    2005-10-01

    Full Text Available Job insecurity is a stressor empirically linked to various negative outcomes, such as impaired work attitudes and adverse health symptoms. Less is known about how these negative consequences can be buffered. The present study investigates whether work-based and non-work based social support moderate the relation between job insecurity and subsequent strain. The results, based on Swedish longitudinal questionnaire data, show that job insecurity predicted strain, even after controlling for demographic variables and baseline levels. Non-work based support moderated the negative effect of job insecurity on mental health complaints and somatic complaints after controlling for baseline levels. The results suggest that employees can benefit from their support network during times of turbulence. Opsomming Werksonsekerheid is ’n stressor wat emperies verband hou met verskeie negatiewe uitkomste soos verlaagde werksgesindhede en nadelige gesondheidssimptome. Minder is bekend oor hoe hierdie negatiewe gevolge gebuffer kan word. Die huidige studie ondersoek of werks gebaseerde en nie-werks gebaseerde sosiale ondersteuning die verhouding tussen werksonsekerheid en daaropvolgende spanning modereer. Die resultate, gebaseer op Sweedse longitudinale vraelysdata, toon dat werksonsekerheid spanning voorpsel het, selfs na die kontrolering vir demografiese veranderlikes en basislyn veranderlikes. Nie-werks gebaseerde ondersteuning het die negatiewe effek van werksonsekerheid op psigiese ongesteldhede en somatiese simptome gemodereer nadat gekontroleer vir basislyn veranderlikes is. Die resultate stel voor dat werknemers voordeel kan trek uit hulle ondersteunings netwerk gedurende tye van turbulensie.

  9. Platform Constellations

    DEFF Research Database (Denmark)

    Staykova, Kalina Stefanova; Damsgaard, Jan

    2016-01-01

    messaging apps KakaoTalk and LINE, we are able to gain valuable insights about the nature of these new constructions and to capture and synthesize their main characteristics in a framework. Our results show that platform constellations possess unique innovative capabilities, which can improve users......’ acquisition and users’ engagement rates as well as unlock new sources of value creation and diversify revenue streams....

  10. Maximum Stress Estimation Model for Multi-Span Waler Beams with Deflections at the Supports Using Average Strains

    OpenAIRE

    Sung Woo Park; Byung Kwan Oh; Hyo Seon Park

    2015-01-01

    The safety of a multi-span waler beam subjected simultaneously to a distributed load and deflections at its supports can be secured by limiting the maximum stress of the beam to a specific value to prevent the beam from reaching a limit state for failure or collapse. Despite the fact that the vast majority of accidents on construction sites occur at waler beams in retaining wall systems, no safety monitoring model that can consider deflections at the supports of the beam is available. In this...

  11. A comparison of the stress-strain process for business owners and nonowners: differences in job demands, emotional exhaustion, satisfaction, and social support.

    Science.gov (United States)

    Tetrick, L E; Slack, K J; Da Silva, N; Sinclair, R R

    2000-10-01

    One hundred sixty licensed morticians were surveyed to examine differences among business owners, managers, and employees on the relations proposed by G. F. Koeske and R. D. Koeske's (1993) stressor-strain-outcome model. Forty-eight percent of the morticians were owners, 16% were managers, and 36% were employees. Owners had less social support from work-related sources and perceived lower levels of role ambiguity and role conflict, less emotional exhaustion, and higher levels of job satisfaction and professional satisfaction than did nonowners. Social support from work-related sources and ownership each moderated the relationship between emotional exhaustion and job satisfaction but not between emotional exhaustion and professional satisfaction. Emotional exhaustion partially mediated the effect of stressors on job satisfaction and professional satisfaction.

  12. 一种应变式超低频微振动测试台%An ultra-low frequency micro-vibration testing platform based on strain-resistance effect

    Institute of Scientific and Technical Information of China (English)

    陈江攀; 程伟; 夏明一

    2014-01-01

    In order to measure micro-vibration of a SADA (solar array drive assembly ) in low and ultra-low frequency zone caused by electromechanical coupling,a six-component testing platform based on strain-resistance effect was developed.Its response characteristic in low frequency zone was outstanding and its installation interface was flexible. The working principle and dynamic calibration method of this platform were introduced in detail.In order to assess the performance of this testing platform,linearity examination,natural frequencies measurement and dynamic testing error examination for it were done.The results showed that linearity errors of eight force sensors are within 3.4% under the action of external force within 1 00N;there are no natural frequencies within 1 00Hz,so that the micro-vibration signals can not be modulated through structural coupling in frequency domain of (0 -1 00Hz );dynamic testing errors of six components are within ±9.6% in frequency domain of (0 -1 00Hz),testing resolutions of three forces and three moments can reach 0.0lN and 0.001 N.m,respectively.%为了测试卫星太阳翼驱动机构低频、超低频区由机电耦合产生的微振动,发明了一种应变式超低频微振动六分量测试台,该测试台低频响应特性好,安装接口灵活。介绍该测试台的工作原理和动态标定方法,并对该测试台进行了线性度检验、固有频率测试以及动态测试误差检验。通过线性度检验可得:在100 N范围内的外力作用下,组成该测试台的八个双孔梁应变式力传感器的线性度相对误差在±3.4%以内;通过固有频率测试可得:该测试台在100 Hz内没有固有频率,不会通过结构耦合对被测微振动信号进行调制;通过动态测试误差检验可得:在频域上0!100 Hz范围内,该测试台对六个分量动态测试的相对误差在±9.6%以内,同时还可以得出该测试台对三个力分量和三个力矩分量

  13. Analysis of Evolution and Implementation of the Private Cloud Support Management Platform in Operators%运营商私有云支撑管理平台的演进与实现分析

    Institute of Scientific and Technical Information of China (English)

    李玮

    2015-01-01

    基于私有云支撑管理平台的功能架构,深入分析了运营商的一般性和特殊性功能需求,并从初期虚拟化管理软件应用入手,结合运营商实践,对私有云管理平台4个阶段的演进历程进行归纳总结。最后,从顶层设计、运维体系、技术选择角度说明了当前运营商在私有云管理平台规划与建设上的关注点和切入点。%Based on the functional architecture of private cloud supporting management platform, the general and special functional requirements in operators were deeply analyzed. And starting from the beginning of the virtualization management software application, combined with the operators practice, the four stages evolution of private cloud management platform were summarized. Finally, the current focus and entry points on the planning and construction of private cloud management platform in operators were illustrated from the aspects of top-level design, operation and maintenance system, technology selection.

  14. Growth inhibition of Cronobacter spp. strains in reconstituted powdered infant formula acidified with organic acids supported by natural stomach acidity.

    Science.gov (United States)

    Zhu, S; Schnell, S; Fischer, M

    2013-09-01

    Cronobacter is associated with outbreaks of rare, but life-threatening cases of meningitis, necrotizing enterocolitis, and sepsis in newborns. This study was conducted to determine the effect of organic acids on growth of Cronobacter in laboratory medium and reconstituted powdered infant formula (PIF) as well as the bacteriostatic effect of slightly acidified infant formula when combined with neonatal gastric acidity. Inhibitory effect of seven organic acids on four acid sensitive Cronobacter strains was determined in laboratory medium with broth dilution method at pH 5.0, 5.5 and 6.0. Acetic, butyric and propionic acids were most inhibitive against Cronobacter in the laboratory medium. The killing effect of these three acids was partially buffered in reconstituted PIF. Under neonatal gastric acid condition of pH 5.0, the slightly acidified formula which did not exert inhibition effect solely reduced significantly the Cronobacter populations. A synergistic effect of formula moderately acidified with organic acid combined with the physiological infant gastric acid was visible in preventing the rapid growth of Cronobacter in neonatal stomach. The study contributed to a better understanding of the inhibitory effect of organic acids on Cronobacter growth in different matrixes and provided new ideas in terms of controlling bacteria colonization and translocation by acidified formula.

  15. Published sequences do not support transfer of oseltamivir resistance mutations from avian to human influenza A virus strains.

    Science.gov (United States)

    Norberg, Peter; Lindh, Magnus; Olofsson, Sigvard

    2015-03-28

    Tamiflu (oseltamivir phosphate ester, OE) is a widely used antiviral active against influenza A virus. Its active metabolite, oseltamivir carboxylate (OC), is chemically stable and secreted into wastewater treatment plants. OC contamination of natural habitats of waterfowl might induce OC resistance in influenza viruses persistently infecting waterfowl, and lead to transfer of OC-resistance from avian to human influenza. The aim of this study was to evaluate whether such has occurred. A genomics approach including phylogenetic analysis and probability calculations for homologous recombination was applied on altogether 19,755 neuraminidase (N1 and N2) genes from virus sampled in humans and birds, with and without resistance mutations. No evidence for transfer of OE resistance mutations from avian to human N genes was obtained, and events suggesting recombination between human and avian influenza virus variants could not be traced in the sequence material studied. The results indicate that resistance in influenza viruses infecting humans is due to the selection pressure posed by the global OE administration in humans rather than transfer from avian influenza A virus strains carrying mutations induced by environmental exposure to OC.

  16. Temperature profiles from expendable bathythermograph (XBT) casts from the BJARNI SAEMUNDSSON and Other Platforms in the North Atlantic Ocean in support of the Integrated Global Ocean Services System (IGOSS) project from 02 February 1974 to 05 April 1974 (NODC Accession 7400351)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — XBT data were collected from the BJARNI SAEMUNDSSON and Other Platforms in support of the Integrated Global Ocean Services System (IGOSS) project. Data were...

  17. Temperature and salinity profiles from CTD casts from NOAA Ship MILLER FREEMAN and other platforms in the North Pacific Ocean, Atlantic Ocean and other seas in support of the Integrated Global Ocean Services System (IGOSS) from 1992-04-01 to 1992-04-30 (NCEI Accession 9200107)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — CTD and other data were collected from NOAA Ship MILLER FREEMAN and other PLATFORMS in support of the Integrated Global Ocean Services System (IGOSS). Data were...

  18. Temperature and salinity profiles from CTD casts from NOAA Ship MILLER FREEMAN and other PLATFORMS from the North Pacific Ocean and North Atlantic Ocean in support of the Integrated Global Ocean Services System (IGOSS) from 1991-05-01 to 1991-05-31 (NCEI Accession 9100108)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — CTD and other data were collected from NOAA Ship MILLER FREEMAN and other PLATFORMS in support of the Integrated Global Ocean Services System (IGOSS). Data were...

  19. Temperature and salinity profiles from CTD casts from NOAA Ship MILLER FREEMAN and other PLATFORMS from the North Pacific Ocean and North Atlantic Ocean in support of the Integrated Global Ocean Services System (IGOSS) from 1991-08-01 to 1991-08-31 (NCEI Accession 9100174)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — CTD and other data were collected from NOAA Ship MILLER FREEMAN and other PLATFORMS in support of the Integrated Global Ocean Services System (IGOSS). Data were...

  20. Temperature and salinity profiles from CTD casts from NOAA Ship MILLER FREEMAN and other PLATFORMS from the North Pacific Ocean and North Atlantic Ocean in support of the Integrated Global Ocean Services System (IGOSS) from 1991-10-01 to 1991-10-31 (NCEI Accession 9100209)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — CTD and other data were collected from NOAA Ship MILLER FREEMAN and other PLATFORMS in support of the Integrated Global Ocean Services System (IGOSS). Data were...

  1. Temperature and salinity profiles from CTD casts from NOAA Ship THOMAS JEFFERSON and other PLATFORMS from the North/South Pacific Ocean, North Atlantic Ocean, and other sea areas in support of the Integrated Global Ocean Services System (IGOSS) from 1991-11-01 to 1991-11-30 (NCEI Accession 9100243)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — CTD and other data were collected from NOAA Ship THOMAS JEFFERSON and other PLATFORMS in support of the Integrated Global Ocean Services System (IGOSS). Data were...

  2. Temperature and salinity profiles from CTD casts from the OKEAN and other PLATFORMS from the North Pacific Ocean, North Atlantic Ocean, and other sea areas in support of the Integrated Global Ocean Services System (IGOSS) from 01 December 1988 to 31 December 1988 (NODC Accession 8900007)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — CTD and other data were collected from the OKEAN and other PLATFORMS in support of the Integrated Global Ocean Services System (IGOSS). Data were collected by US...

  3. Temperature and salinity profiles from CTD casts from NOAA Ship MILLER FREEMAN and other PLATFORMS from a World-Wide Distribution in support of the Integrated Global Ocean Services System (IGOSS) from 1991-07-01 to 1991-07-31 (NCEI Accession 9100146)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — CTD and other data were collected from NOAA Ship MILLER FREEMAN and other PLATFORMS in support of the Integrated Global Ocean Services System (IGOSS). Data were...

  4. Oceanographic station data from bottle casts from the USS SAGACITY and Other Platforms in the Bering Sea and other locations in support of the Fleet Observations of Oceanographic Data (FLOOD) project from 01 December 1965 to 19 August 1968 (NODC Accession 6900268)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Oceanographic station data were collected from the USS SAGACITY and Other Platforms in support of the Fleet Observations of Oceanographic Data (FLOOD) project. Data...

  5. Temperature profiles from mechanical bathythermograph (MBT) casts from the USS GEIGER and Other Platforms in the North Pacific Ocean in support of the Fleet Observations of Oceanographic Data (FLOOD) project on from 24 May 1962 to 20 March 1969 (NODC Accession 6900570)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — MBT data were collected from the USS GEIGER and Other Platforms in support of the Fleet Observations of Oceanographic Data (FLOOD) project. Data were collected by US...

  6. Temperature and salinity profiles from CTD casts from the OKEAN and other PLATFORMS from the North Pacific Ocean, North/South Atlantic Ocean, and other sea areas in support of the Integrated Global Ocean Services System (IGOSS) from 01 November 1988 to 30 November 1988 (NODC Accession 8900001)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — CTD and other data were collected from the OKEAN and other PLATFORMS in support of the Integrated Global Ocean Services System (IGOSS). Data were collected by US...

  7. Temperature and salinity profiles from CTD casts from the OKEAN and other PLATFORMS from the North/South Atlantic Ocean and other sea areas in support of the Integrated Global Ocean Services System (IGOSS) from 01 October 1989 to 31 October 1989 (NODC Accession 8900296)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — CTD and other data were collected from the OKEAN and other PLATFORMS in support of the Integrated Global Ocean Services System (IGOSS). Data were collected by US...

  8. Temperature and salinity profiles from CTD casts from the OKEAN and other PLATFORMS from the North Pacific Ocean, North Atlantic Ocean, and other sea areas in support of the Integrated Global Ocean Services System (IGOSS) from 01 July 1989 to 31 July 1989 (NODC Accession 8900256)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — CTD and other data were collected from the OKEAN and other PLATFORMS in support of the Integrated Global Ocean Services System (IGOSS). Data were collected by US...

  9. Temperature and salinity profiles from expendable bathythermograph (XBT) and CTD casts from NOAA Ship MILLER FREEMAN and other Platforms from Coastal Waters of Washington/Oregon and other locations in support of the Integrated Global Ocean Services System (IGOSS) from 1977-07-12 to 1983-07-26 (NCEI Accession 8300102)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — XBT and CTD data were collected from NOAA Ship MILLER FREEMAN and other Platforms in support of the Integrated Global Ocean Services System (IGOSS) project. Data...

  10. Temperature profiles from expendable bathythermograph (XBT) casts from NOAA Ship RAINIER and other platforms in the Indian Ocean, North Atlantic Ocean, and North Pacific Ocean in support of the Integrated Global Ocean Services System (IGOSS) project from 1981-10-01 to 1981-12-20 (NCEI Accession 8200001)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — XBT data were collected from NOAA Ship RAINIER and other platforms in support of the Integrated Global Ocean Services System (IGOSS) project. Data were collected by...

  11. Temperature profiles from expendable bathythermograph (XBT) casts from NOAA Ship RAINIER and other platforms in a World-wide distribution in support of the Integrated Global Ocean Services System (IGOSS) project from 1982-10-02 to 1983-03-16 (NCEI Accession 8300044)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — XBT data were collected from NOAA Ship RAINIER and other platforms in support of the Integrated Global Ocean Services System (IGOSS) project. Data were collected by...

  12. Temperature profiles from expendable bathythermograph (XBT) casts DIAMANTINA and other Platforms from a World-Wide Distribution in support of the Integrated Global Ocean Services System (IGOSS) and the Pacific Acoustic Research Kaneohe-Alaska (PARKA) from 12 December 1966 to 29 September 1974 (NODC Accession 7500700)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — XBT data were collected from the DIAMANTINA and other Platforms in support of the Integrated Global Ocean Services System (IGOSS) and the Pacific Acoustic Research...

  13. Temperature profiles from expendable bathythermograph (XBT) casts from NOAA Ship ALBATROSS IV and other Platforms in the North Pacific Ocean in support of the Integrated Global Ocean Services System (IGOSS) from 1982-06-02 to 1983-06-22 (NCEI Accession 8300088)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — XBT data were collected from NOAA Ship ALBATROSS IV and other Platforms in support of the Integrated Global Ocean Services System (IGOSS). Data were collected by the...

  14. Temperature and salinity profiles from CTD casts from the VOLNA and other PLATFORMS from the North/South Pacific Ocean, North Atlantic Ocean, and other sea areas in support of the Integrated Global Ocean Services System (IGOSS) from 01 February 1989 to 27 February 1989 (NODC Accession 8900053)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — CTD and other data were collected from the VOLNA and other PLATFORMS in support of the Integrated Global Ocean Services System (IGOSS). Data were collected by US...

  15. Temperature profiles from expendable bathythermograph (XBT) casts from the ANTON DOHRN II and Other Platforms in the North Atlantic Ocean in support of the Integrated Global Ocean Services System (IGOSS) from 30 July 1976 to 23 May 1978 (NODC Accession 7800533)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — XBT data were collected from the ANTON DOHRN II and Other Platforms in support of the Integrated Global Ocean Services System (IGOSS). Data were collected by the...

  16. Temperature profiles from mechanical bathythermograph (MBT) casts from the D. EDWARDS and Other Platforms in the North Pacific Ocean and other locations in support of the Fleet Observations of Oceanographic Data (FLOOD) project from 20 May 1963 to 28 November 1967 (NODC Accession 6900330)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — MBT data were collected from the D. EDWARDS and Other Platforms in support of the Fleet Observations of Oceanographic Data (FLOOD) project. Data were collected by...

  17. Temperature profiles from mechanical bathythermograph (MBT) casts from the USS FIRM and Other Platforms in the North Pacific Ocean in support of the Fleet Observations of Oceanographic Data (FLOOD) project from 28 June 1969 to 12 July 1969 (NODC Accession 7000363)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — MBT data were collected from the USS FIRM and other Platforms in support of the Fleet Observations of Oceanographic Data (FLOOD) project. Data were collected by US...

  18. A practice scaffolding interactive platform

    DEFF Research Database (Denmark)

    Bundsgaard, Jeppe

    2009-01-01

    , structures the students' activity, and interactively supports subject learning. A PracSIP facilitates students' development of complex competencies, and at the same time it supports the students' development of skills defined in the curriculum. The paper introduces the concept, presents the theoretical......A Practice Scaffolding Interactive Platform (PracSIP) is a social learning platform which supports students in collaborative project based learning by simulating a professional practice. A PracSIP puts the core tools of the simulated practice at the students' disposal, it organizes collaboration...

  19. Comparison of stress, strain, and elastic properties for porous silicon layers supported by substrate and corresponding membranes

    Science.gov (United States)

    Dariani, R. S.; Nazari, M.

    2016-09-01

    This paper describes characterization of mechanical properties of porous silicon (PS) layers with different porosities using high resolution XRD. The XRD measurement determined various mechanical properties of PS such as; Young modulus, Poisson's ratio, and lattice parameter expansion. Our results indicated that mechanical properties reduce with increasing porosity. Also, the mechanical properties of two different porous layers, either supported by or detached from the substrate were examined. Comparison of the two porous layers showed that the constraint in the interatomic spacing is the origin of the lattice constant expansion in the planes perpendicular to the surface. This phenomenon can be useful for gas sensor applications.

  20. 电力市场与电力系统的动态交互仿真平台(二)支撑层设计%Dynamic Simulation Platform for Power Market and Power System Part Two Support Layer Design

    Institute of Scientific and Technical Information of China (English)

    谢东亮; 薛禹胜; 薛峰; 罗剑波

    2011-01-01

    This three-part paper introduces the design of the dynamic simulation platform for power market &. Power system (DSPMPS). Based on the function design introduced in part one, the application programming interface is created to enable the integration of internal components, in order to support the development of server or client side simulation contents. IT technologies for visualization and networking are used to create a multi-player game environment. Event-driven and service-oriented mechanisms are applied to simplify the dynamic interactions among objects modeled in multi-time, space and targeting parameter scales. These technologies finally lead to a standardized interface of the support layer, based on which even end users can manipulate building blocks to customize applications efficiently. The platform is also open to other software platforms for interoperations through a multi-purpose network complied with international communication protocols to access multi-field contents and multi-core computation resources. The next paper will introduce the method to develop visual and interactive simulation applications for generalized congestion studies by creating and using building blocks and other properties based on the support layer.%由3篇论文组成的系列文章介绍了电力市场与电力系统动态交互仿真平台(dynamicsimulation platform for power market & power system,DSPMPS).在第1篇关于功能设计的基础上,文中建立了仿真应用开发接口,以支持在服务器端及客户端扩展各种内核组件.利用IT技术,以可视化、网络化的实验形式来建立多角色博弈;以事件驱动和面向服务机制模拟多尺度时间、空间、目标的复杂动态交互;以标准化、积木化的形式实现高效灵活的用户定制及扩展开发;按国际标准创建开放且高效的多核运算架构.下一篇将介绍以软件积木方式,在支撑层上搭建反映广义阻塞、支持图形化决策试探的各种仿真应用.

  1. 云平台支撑的科技服务价值网络的商业模式研究%Value Network Mode of Technological Services Supported by Cloud platforms

    Institute of Scientific and Technical Information of China (English)

    张龙; 何健

    2014-01-01

    As global economy and technology are progressing fast, enterprises have to promote the technology level for a sustainable devel-opment and establish customer-centered value networks to meet the market demand. Cloud platforms and value network could provide a lot of effective and rapid information. Cloud platform-supported value network offers necessary data and calculation support for decision making of technological service providers, such as budget decisions of management accounting and other reasonable operational decisions. In a commercial mode of cloud platform-supported value network, the characteristics of value network in terms of share, data processing, and multi-platform login and the cloud computing function could help enterprises survive intensified market competition.%随着全球经济和科技的飞速发展,企业要想长久发展必须提高自身技术水平,并以客户为中心构建企业价值网络来适应市场。云平台与价值网络为我们提供了诸多有效的快捷信息。云平台支撑下的科技服务企业价值网络为企业战略决策提供必要数据与运算支持,便于管理会计的预算决策以及企业的合理决策。在云平台支撑下的科技服务企业价值网络的商业模式下,我们要利用价值网络的共享性、对数据的处理性、支持多平台登录的特性以及云计算的功能,力争在愈演愈烈的市场竞争中立足。

  2. Overall design of smart campus supporting platform based on cloud technology%基于云技术支持的智慧校园支撑平台的总体设计

    Institute of Scientific and Technical Information of China (English)

    王欣; 景波

    2016-01-01

    该文研究基于云技术支持的智慧校园支撑平台,分析其优势,并给出总体设计策略,最后分析总体设计的效益。结果表明,改革创新智慧校园工作,优化设计基于云技术支持的智慧校园平台,不仅可以向广大师生提供便捷的个性化信息服务,还可以依据校园内师生工作学习情况,合理规划校园支撑平台内的管理系统,提升智慧校园总体设计水平,发挥积极影响。%With the execution of the current education reform and the promotion of modern cloud technology,reform and in⁃novation of the wisdom campus work,and optimization design of the intelligent campus platform based on cloud technology can not only provide convenient personalized information service for the majority of teachers and students,but also reasonably plan the management system of campus supporting platform according to the work and study status of the teachers and students in campus,and enhance the overall design level of the smart campus for exertion of positive influence. The overall design of the campus supporting platform based on cloud technology is analyzed in this paper.

  3. The Innovative Capabilities Of Digital Payment Platforms

    DEFF Research Database (Denmark)

    Kazan, Erol

    2015-01-01

    the support for open innovation. The proposed model has been employed in a comparative case study between two digital payment platforms: Apple Pay and Google Wallet. The findings suggest that digital payment platforms make use of boundary resources to be highly integrative or integratable, which supports...

  4. Common tester platform concept.

    Energy Technology Data Exchange (ETDEWEB)

    Hurst, Michael James

    2008-05-01

    This report summarizes the results of a case study on the doctrine of a common tester platform, a concept of a standardized platform that can be applicable across the broad spectrum of testing requirements throughout the various stages of a weapons program, as well as across the various weapons programs. The common tester concept strives to define an affordable, next-generation design that will meet testing requirements with the flexibility to grow and expand; supporting the initial development stages of a weapons program through to the final production and surveillance stages. This report discusses a concept investing key leveraging technologies and operational concepts combined with prototype tester-development experiences and practical lessons learned gleaned from past weapons programs.

  5. OGC Collaborative Platform undercover

    Science.gov (United States)

    Buehler, G.; Arctur, D. K.; Bermudez, L. E.

    2012-12-01

    The mission of the Open Geospatial Consortium (OGC) is to serve as a global forum for the collaboration of developers and users of spatial data products and services, and to advance the development of international standards for geospatial interoperability. The OGC coordinates with over 400 institutions in the development of geospatial standards. OGC has a dedicated staff supported by a Collaborative Web Platform to enable sophisticated and successful coordination among its members. Since its origins in the early 1990s, the OGC Collaborative Web Platform has evolved organically to be the collaboration hub for standards development in the exchange of geospatial and related types of information, among a global network of thousands of technical, scientific and management professionals spanning numerous disparate application domains. This presentation describes the structure of this collaboration hub, the relationships enabled (both among and beyond OGC members), and how this network fits in a broader ecosystem of technology development and information standards organizations.

  6. Overproduction of Thermus sp. Strain T2 β-Galactosidase in Escherichia coli and Preparation by Using Tailor-Made Metal Chelate Supports

    Science.gov (United States)

    Pessela, Benevides C. C.; Vian, Alejandro; Mateo, César; Fernández-Lafuente, Roberto; García, José L.; Guisán, José M.; Carrascosa, Alfonso V.

    2003-01-01

    A novel thermostable chimeric β-galactosidase was constructed by fusing a poly-His tag to the N-terminal region of the β-galactosidase from Thermus sp. strain T2 to facilitate its overexpression in Escherichia coli and its purification by immobilized metal-ion affinity chromatography (IMAC). The poly-His tag fusion did not affect the activation, kinetic parameters, and stability of the β-galactosidase. Copper-iminodiacetic acid (Cu-IDA) supports enabled the most rapid adsorption of the His-tagged enzyme, favoring multisubunit interactions, but caused deleterious effects on the enzyme stability. To improve the enzyme purification a selective one-point adsorption was achieved by designing tailor-made low-activated Co-IDA or Ni-IDA supports. The new enzyme was not only useful for industrial purposes but also has become an excellent model to study the purification of large multimeric proteins via selective adsorption on tailor-made IMAC supports. PMID:12676671

  7. Minimization of outage probability of WiMAX link supported by laser link between a high-altitude platform and a satellite.

    Science.gov (United States)

    Arnon, Shlomi

    2009-07-01

    Various technologies for the implementation of a WiMAX (IEEE802.16) base station on board a high-altitude platform (HAP) are currently being researched. The network configuration under consideration includes a satellite, several HAPs, and subscribers on the ground. The WiMAX base station is positioned on the satellite and connects with the HAP via an analog RF over-laser communication (LC) link. The HAPs house a transparent transponder that converts the optic signal to a WiMAX RF signal and the reverse. The LC system consists of a laser transmitter and an optical receiver that need to be strictly aligned to achieve a line-of-sight link. However, mechanical vibration and electronic noise in the control system challenge the transmitter-receiver alignment and cause pointing errors. The outcome of pointing errors is fading of the received signal, which leads to impaired link performance. In this paper, we derive the value of laser transmitter gain that can minimize the outage probability of the WiMAX link. The results indicate that the optimum value of the laser transmitter gain is not a function of the pointing error statistics.

  8. Security Support Platform for Intelligent Decision System of Real Estate%房地产智能决策系统安全支撑平台

    Institute of Scientific and Technical Information of China (English)

    郑卜之; 段斌

    2012-01-01

    In this paper, a scheme of message signature and encryption based on Simple Object Access Protocol (SOAP) is designed for the intelligent decision-making system of real estate to solve communication security issues when interacting data with other heterogeneous systems. Referring to the national recommendations upon the information security area in the e-government implementing process and considering both efficiency and security of communication procedures between two endpoints, we screened and integrated various security methods, then implemented a security platform with C# and WSE3.0. The experiment shows its good safety, reliability, flexibility, manageability, and scalability.%用简单对象访问协议(SOAP)消息签名加密的方案来解决房地产智能决策系统在跟其他异构系统数据交互时的通信安全的问题.参照国家对电子政务实施过程中信息安全的建议,综合考虑效率和安全性,通过对各种不同安全方案进行筛选和整合.并在C#平台和WSE3.0开发环境下,实现安全支撑平台具有很好的安全性、可靠性、灵活性、可管理性和可扩充性.

  9. The Innovative Capabilities Of Digital Payment Platforms

    DEFF Research Database (Denmark)

    Kazan, Erol

    2015-01-01

    the support for open innovation. The proposed model has been employed in a comparative case study between two digital payment platforms: Apple Pay and Google Wallet. The findings suggest that digital payment platforms make use of boundary resources to be highly integrative or integratable, which supports...... the intended conjoint commercialization efforts. Furthermore, the architectural design of digital platforms impacts the access to commercialization, resulting to an exclusion or inclusion strategy in accessing value opportunities. Our findings contribute to the open innovation and digital platform literature...

  10. OTEC Cold Water Pipe-Platform Subsystem Dynamic Interaction Validation

    Energy Technology Data Exchange (ETDEWEB)

    Varley, Robert [Lockheed Martin Corporation, Manassas, VA (United States); Halkyard, John [John Halkyard and Associates, Houston, TX (United States); Johnson, Peter [BMT Scientific Marine Services, Inc., Houston, TX (United States); Shi, Shan [Houston Offshore Engineering, Houston, TX (United States); Marinho, Thiago [Federal Univ. of Rio de Janeiro (Brazil). LabOceano

    2014-05-09

    A commercial floating 100-megawatt (MW) ocean thermal energy conversion (OTEC) power plant will require a cold water pipe (CWP) with a diameter of 10-meter (m) and length of up to 1,000 m. The mass of the cold water pipe, including entrained water, can exceed the mass of the platform supporting it. The offshore industry uses software-modeling tools to develop platform and riser (pipe) designs to survive the offshore environment. These tools are typically validated by scale model tests in facilities able to replicate real at-sea meteorological and ocean (metocean) conditions to provide the understanding and confidence to proceed to final design and full-scale fabrication. However, today’s offshore platforms (similar to and usually larger than those needed for OTEC applications) incorporate risers (or pipes) with diameters well under one meter. Secondly, the preferred construction method for large diameter OTEC CWPs is the use of composite materials, primarily a form of fiber-reinforced plastic (FRP). The use of these material results in relatively low pipe stiffness and large strains compared to steel construction. These factors suggest the need for further validation of offshore industry software tools. The purpose of this project was to validate the ability to model numerically the dynamic interaction between a large cold water-filled fiberglass pipe and a floating OTEC platform excited by metocean weather conditions using measurements from a scale model tested in an ocean basin test facility.

  11. The Prodiguer Messaging Platform

    Science.gov (United States)

    Denvil, S.; Greenslade, M. A.; Carenton, N.; Levavasseur, G.; Raciazek, J.

    2015-12-01

    CONVERGENCE is a French multi-partner national project designed to gather HPC and informatics expertise to innovate in the context of running French global climate models with differing grids and at differing resolutions. Efficient and reliable execution of these models and the management and dissemination of model output are some of the complexities that CONVERGENCE aims to resolve.At any one moment in time, researchers affiliated with the Institut Pierre Simon Laplace (IPSL) climate modeling group, are running hundreds of global climate simulations. These simulations execute upon a heterogeneous set of French High Performance Computing (HPC) environments. The IPSL's simulation execution runtime libIGCM (library for IPSL Global Climate Modeling group) has recently been enhanced so as to support hitherto impossible realtime use cases such as simulation monitoring, data publication, metrics collection, simulation control, visualizations … etc. At the core of this enhancement is Prodiguer: an AMQP (Advanced Message Queue Protocol) based event driven asynchronous distributed messaging platform. libIGCM now dispatches copious amounts of information, in the form of messages, to the platform for remote processing by Prodiguer software agents at IPSL servers in Paris. Such processing takes several forms: Persisting message content to database(s); Launching rollback jobs upon simulation failure; Notifying downstream applications; Automation of visualization pipelines; We will describe and/or demonstrate the platform's: Technical implementation; Inherent ease of scalability; Inherent adaptiveness in respect to supervising simulations; Web portal receiving simulation notifications in realtime.

  12. NASA's geostationary communications platform program

    Science.gov (United States)

    Ramler, J.; Durrett, R.

    1984-01-01

    This paper reviews recent trends in communications satellites and explains NASA's current interest in geostationary communications platforms. Large communications platforms capable of supporting multiple payloads with common utilities have been examined in a number of studies since 1974 and appear to offer a number of potential advantages. In 1981, an Industry Briefing and Workshop sponsord by NASA focused on the institutional, operational and technical issues that will influence the implementation of geostationary platforms. The workshop identified numerous issues and problem areas that needed more detailed study. To address the issues/problems identified, a NASA geostationary communications platform program has been developed. This program is described, focusing on the initial studies to be performed.

  13. Identification of platform levels

    DEFF Research Database (Denmark)

    Mortensen, Niels Henrik

    2005-01-01

    reduction, ability to launch a wider product portfolio without increasing resources and reduction of complexity within the whole company. To support the multiple product development process, platform based product development has in many companies such as Philips, VW, Ford etc. proven to be a very effective...... and efficient tool. Transforming product development from single to multiple product development is a significant change in product development often involving major changes of product models, procedures and organization. In the area of product models a set of new models has to be introduced, e.g. models...

  14. 南极科考智能支撑平台监控系统的设计与实现%The Design and Realization of the Monitoring System of the Intellective Antarctic Scientific Research Supporting Platform

    Institute of Scientific and Technical Information of China (English)

    汤刘杰; 朱蔚萍; 张侃健; 魏海坤

    2012-01-01

    南极科考智能支撑平台是由我国首座独立自主研发使用于极端条件下的能源支撑平台.针对低温低压的特殊环境,为了确保关键器件能够正常工作.系统的可靠性及安全性变得尤为重要,因此监控系统采用了温度控制、冗余设计等策略.从系统硬件选型、搭建进行了详细分析并加以实验验证,从而确保系统成功运行.%The intellective Antarctic scientific research supporting platform is China's first energy platform developed independently and used under extreme conditions.It deals with the special environment of low temperature and pressure to guarantee the regular work of the key components.As a result, the reliability and security of the system become especially important, therefore, the temperature control, the redundant design and other strategies is used in the monitoring system.We have made detailed analysis and experimental verification from the system hardware type selection to construction in this paper which guarantees the success of the system operation.

  15. 利用PubMed构建医药企业文献支持平台%The Construction of Literature Supporting Platform for Drug Enterprises Utilizing PubMed

    Institute of Scientific and Technical Information of China (English)

    胡书明

    2012-01-01

    基于PubMed程序接口进行二次程序开发,从需求分析、基础架构、实现流程等方面介绍医药企业文献支持平台的构建,实现企业特色文献资源的积累、及时更新以及集约化使用。%The paper carries out secondary program development based on PubMed interfaces,introduces the construction of literature supporting platform for drug enterprises from the aspects of requirements analysis,basic framework,realization process and so on,so as to realize accumulation,timely update and intensive utilization of characteristic literature resources in enterprises.

  16. Towards a service platform for mobile context-aware applications

    NARCIS (Netherlands)

    Dockhorn Costa, P.; Ferreira Pires, L.; Sinderen, van M.J.; Pereira Filho, J.G.; Mostefaoui, S.K.; Maarmar, Z.; Rana, O.F.

    2004-01-01

    Context-aware services platforms aim at supporting the handling of contextual information in order to provide better user-tailored services. This paper proposes a novel services platform architecture to support mobile context-aware applications, giving emphasis to the configurability of the platform

  17. The Utilisation of Pisang Island as a Platform to Support the Current Safety and Security Needs of Marine Navigation in the Straits of Malacca

    Directory of Open Access Journals (Sweden)

    Ahmad Faizal Ahmad Fuad

    2017-06-01

    Full Text Available Current marine navigational practice relies less on long-range visual marine signals such as lighthouses for reference purposes. This is due to the availability of Global Navigation Satellite Systems (GNSS, which are integrated with other navigational aids on ships. Therefore, the objective of this study is to review the function of Pisang Island lighthouse and to propose the most relevant use of Pisang Island for current navigational needs. The function of the lighthouse was reviewed according to the IALA Navigational Guide and the AIS data image. The result showed that the most suitable navigational use of the lighthouse is to act as a reference for Line of Position (LOP. The AIS data image indicated that mariners are not using Pisang Island lighthouse for LOP. The trend in the Straits of Malacca (SoM was compared with the trend in the Straits of Dover, UK. The selected experts verified that LOP was not practised there. As a specific example, a tanker ship route in the South China Sea was used to further support that LOP was not practised. This evidence supported the view that Pisang Island lighthouse is less relevant for current navigational practice and does not directly support the coastal state VTS operation and the establishment of the marine electronic highway. Furthermore, the existing shore-based VTS radar has limitations on range and the detection of targets near Pisang Island. Therefore, this study proposes the establishment of a new radar station on Pisang Island at the existing site of the lighthouse. The proposed new radar station on Pisang Island will add to the existing coverage of the VTS radar, bridging the coverage gaps to overcome the weakness of the existing shore-based radar and improve the safety and security of marine navigation in the SoM.

  18. 基于云计算的图书馆大数据分析和决策支持平台构建%Construction of Big Data Analysis and Decision Support Platform for Library Based on Cloud Computing

    Institute of Scientific and Technical Information of China (English)

    陈臣

    2016-01-01

    随着大数据时代的到来,图书馆中的数据量呈现爆炸式增长,由于大数据具有多类型和复杂性,给图书馆的大数据分析与决策支持带来了极大的挑战。本文介绍了大数据和云计算的定义,构建了基于云计算的图书馆大数据分析与决策平台。该平台大幅提高了图书馆海量数据的处理能力,能够发现图书馆大数据之间存在的关系和规则,可有效预测图书馆服务未来的发展趋势,从而增强图书馆服务决策的准确性和科学性。%With the coming of Big Data era, the quantity of data in library is growing exponentially. Multi-type and complexity of big data brings big challenge to big data analysis and decision support of library. Firstly, this paper introduces the definition of Big Data and cloud computing, and then constructs a Big Data analysis and decision support platform for library based on cloud com-puting. The platform greatly improves the processing capability of mass data of library, which can find the relationship and rule be-tween Big Data to predict the future trend of library services, and improve veracity and scientificity of the decision-making in li-brary services.

  19. 生物恐怖事件计算实验支持平台及研究实例%Computational experiment supported platform for bioterrorism events and research examples

    Institute of Scientific and Technical Information of China (English)

    许晴; 祖正虎; 张文斗; 刘健; 徐致靖; 黄培堂; 郑涛

    2011-01-01

    Quantitative analysis of the process of bioterrorism events is great significance for national biosecurity strategies and emergency response to such attacks. This article focuses on providing support for quantificational analysis of the whole process of various bioterrorism events, including providing infrastructure datasets, models and algorithm system-executing computational experiments-reproducing scenarios shown in 3D,and constructing a bioterrorism events computational experiment supported platform. On the basis of the platform, we make a case study of a potential anthrax aerosol attack a-gainst Beijing and assess the hazard.%定量分析研究生物恐怖事件过程对国家生物安全战略和有效处置生物恐怖事件具有重要意义.本研究着眼于为定量研究各种类型生物恐怖事件过程提供从基础数据、模型及算法体系一计算实验一情景重现、三维可视化显示的全过程支持,建立生物恐怖事件计算实验支持平台,并以此平台为基础,以北京城区遭受炭疽芽孢杆菌气溶胶袭击为想定进行实例研究并对所造成的危害进行评估.

  20. RESEARCH AND APPLICATION OF SOGRID CLOUD PLATFORM SUPPORTING BUSINESS SYSTEM OF STATE GRID%支撑国网业务系统的 SoGrid 云平台研究与应用

    Institute of Scientific and Technical Information of China (English)

    张鹏; 王伟; 熊力; 张栋栋

    2016-01-01

    In order to promote the integration and normalisation of state grid business system,we propose the cloud era-oriented SoGrid, which is a component development platform for enterprise applications.This paper mainly introduces the overall architecture of SoGrid cloud platform,functional design of each process module,practical application and performance analyses on business system of enterprise sector as well as the prospects of next step work.Through the division in the field of business and the accumulation of components,the platform has rich assembled component library,constructs services group and comprehensive running monitor containers,supports visualised frame service configuration and interface development,implements the reusability of component and the changing requirement in various business scenes, and provides a strong support for the system developments in regard to each business centre.%为促进国家电网公司业务系统构建的集成性和规范性,提出面向云时代的企业级应用构件开发平台 SoGrid。重点介绍SoGrid 云平台的整体架构,各个流程模块的功能设计,在企业部门的业务系统上的实际应用与性能分析以及下一步的工作展望。通过对业务领域的划分和构件的积累,该平台具有丰富的可组装构件库,构造服务群和全面的运行监控容器,支持可视化的框架服务配置和界面开发,实现了构件的可复用性和多种业务场景的变化需求,为各业务中心的系统开发提供了有效的支撑。

  1. "Movable platform" - the idea and energy consumption

    OpenAIRE

    Czesław PYPNO; Margielewicz, Jerzy; Gąska, Damian

    2011-01-01

    This paper presents the application of the concept of moving sidewalks at railway stations (the movable platform) including the calculation of electricity consumption. Particular focus was placed on issue of energy profit and loss in two stages - through the loss (consumption) of energy by using a moving sidewalk at a railway station platform and the profit (reduced consumption) of energy, by the lack of having to start the train, that supports movable platform, from the initial speed of 0 km/h.

  2. Building a platform for translational research in chronic noncommunicable diseases to address population health: lessons from NHLBI supported CRONICAS in Peru.

    Science.gov (United States)

    Miranda, J Jaime; Bernabé-Ortiz, Antonio; Diez-Canseco, Francisco; Málaga, Germán; Cardenas, María K; Carrillo-Larco, Rodrigo M; Pesantes, M Amalia; Araya, Ricardo; Boggio, Oscar; Checkley, William; García, Patricia J; León-Velarde, Fabiola; Lescano, Andrés G; Montori, Victor; Pan, William; Rivera-Chira, Maria; Sacksteder, Katherine; Smeeth, Liam; García, Héctor H; Gilman, Robert H

    2015-03-01

    The CRONICAS Centre of Excellence in Chronic Diseases, based at Universidad Peruana Cayetano Heredia, was created in 2009 with support from the U.S. National Heart, Lung, and Blood Institute (NHLBI). The vision of CRONICAS is to build a globally recognized center of excellence conducting quality and innovative research and generating high-impact evidence for health. The center's identity is embedded in its core values: generosity, innovation, integrity, and quality. This review has been structured to describe the development of the CRONICAS Centre, with a focus on highlighting the ongoing translational research projects and capacity-building strategies. The CRONICAS Centre of Excellence is not a risk-averse organization: it benefits from past experiences, including past mistakes, and improves upon them and thus challenges traditional research approaches. This ethos and environment are key to fostering innovation in research.

  3. The Geohazards Exploitation Platform

    Science.gov (United States)

    Laur, Henri; Casu, Francesco; Bally, Philippe; Caumont, Hervé; Pinto, Salvatore

    2016-04-01

    The Geohazards Exploitation Platform, or Geohazards TEP (GEP), is an ESA originated R&D activity of the EO ground segment to demonstrate the benefit of new technologies for large scale processing of EO data. This encompasses on-demand processing for specific user needs, systematic processing to address common information needs of the geohazards community, and integration of newly developed processors for scientists and other expert users. The platform supports the geohazards community's objectives as defined in the context of the International Forum on Satellite EO and Geohazards organised by ESA and GEO in Santorini in 2012. The GEP is a follow on to the Supersites Exploitation Platform (SSEP) an ESA initiative to support the Geohazards Supersites & Natural Laboratories initiative (GSNL). Today the GEP allows to exploit 70+ Terabyte of ERS and ENVISAT archive and the Copernicus Sentinel-1 data available on line. The platform has already engaged 22 European early adopters in a validation activity initiated in March 2015. Since September, this validation has reached 29 single user projects. Each project is concerned with either integrating an application, running on demand processing or systematically generating a product collection using an application available in the platform. The users primarily include 15 geoscience centres and universities based in Europe: British Geological Survey (UK), University of Leeds (UK), University College London (UK), ETH University of Zurich (CH), INGV (IT), CNR-IREA and CNR-IRPI (IT), University of L'Aquila (IT), NOA (GR), Univ. Blaise Pascal & CNRS (FR), Ecole Normale Supérieure (FR), ISTERRE / University of Grenoble-Alpes (FR). In addition, there are users from Africa and North America with the University of Rabat (MA) and the University of Miami (US). Furthermore two space agencies and four private companies are involved: the German Space Research Centre DLR (DE), the European Space Agency (ESA), Altamira Information (ES

  4. Microgravity Platforms

    Science.gov (United States)

    Del Basso, Steve

    2000-01-01

    The world's space agencies have been conducting microgravity research since the beginning of space flight. Initially driven by the need to understand the impact of less than- earth gravity physics on manned space flight, microgravity research has evolved into a broad class of scientific experimentation that utilizes extreme low acceleration environments. The U.S. NASA microgravity research program supports both basic and applied research in five key areas: biotechnology - focusing on macro-molecular crystal growth as well as the use of the unique space environment to assemble and grow mammalian tissue; combustion science - focusing on the process of ignition, flame propagation, and extinction of gaseous, liquid, and solid fuels; fluid physics - including aspects of fluid dynamics and transport phenomena; fundamental physics - including the study of critical phenomena, low-temperature, atomic, and gravitational physics; and materials science - including electronic and photonic materials, glasses and ceramics, polymers, and metals and alloys. Similar activities prevail within the Chinese, European, Japanese, and Russian agencies with participation from additional international organizations as well. While scientific research remains the principal objective behind these program, all hope to drive toward commercialization to sustain a long range infrastructure which .benefits the national technology and economy. In the 1997 International Space Station Commercialization Study, conducted by the Potomac Institute for Policy Studies, some viable microgravity commercial ventures were identified, however, none appeared sufficiently robust to privately fund space access at that time. Thus, government funded micro gravity research continues on an evolutionary path with revolutionary potential.

  5. 云计算数据安全支撑平台架构研究%The Research of Cloud Computing Data Security Support Platform Architecture

    Institute of Scientific and Technical Information of China (English)

    张大朋; 蔡克; 张敏; 徐震

    2011-01-01

    As cloud providers have priority access to data, it is difficult to guarantee the confidentiality and integrity of users' data. For this problem the paper presents an architecture to protect user data security by encryption. Searching cipher text and integrity verification will be used to ensure the availability and integrity of users' data. This mechanism provides reliable security support for the massive data in the cloud computing system.%由于云服务提供商拥有对数据的优先访问权,用户数据的机密性和完整性很难得到保证.针对此问题构建了一种使用加密机制保护云数据安全的体系结构.使用密文检索和完整性验证来保证云用户数据的可用性和完整性,为云计算系统中海量数据提供用户可信赖的安全支撑.

  6. Selecting a Virtual World Platform for Learning

    Science.gov (United States)

    Robbins, Russell W.; Butler, Brian S.

    2009-01-01

    Like any infrastructure technology, Virtual World (VW) platforms provide affordances that facilitate some activities and hinder others. Although it is theoretically possible for a VW platform to support all types of activities, designers make choices that lead technologies to be more or less suited for different learning objectives. Virtual World…

  7. Product Platform Modeling

    DEFF Research Database (Denmark)

    Pedersen, Rasmus

    on the notion that reuse and encapsulation of platform elements are fundamental characteristics of a product platform. Reuse covers the desire to reuse and share certain assets across a family of products and/or across generations of products. Product design solutions and principles are often regarded...... as important assets in a product platform, yet activities, working patterns, processes and knowledge can also be reused in a platform approach. Encapsulation is seen as a process in which the different elements of a platform are grouped into well defined and self-contained units which are decoupled from each......This PhD thesis has the title Product Platform Modelling. The thesis is about product platforms and visual product platform modelling. Product platforms have gained an increasing attention in industry and academia in the past decade. The reasons are many, yet the increasing globalisation...

  8. Design, implementation and practice of JBEI-ICE: an open source biological part registry platform and tools

    OpenAIRE

    Ham, Timothy S.; Dmytriv, Zinovii; Plahar, Hector; Chen, Joanna (Kuei-Yen); Nathan J Hillson; Jay D Keasling

    2012-01-01

    The Joint BioEnergy Institute Inventory of Composable Elements (JBEI-ICEs) is an open source registry platform for managing information about biological parts. It is capable of recording information about ‘legacy’ parts, such as plasmids, microbial host strains and Arabidopsis seeds, as well as DNA parts in various assembly standards. ICE is built on the idea of a web of registries and thus provides strong support for distributed interconnected use. The information deposited in an ICE install...

  9. Job Strain and Determinants in Staff Working in Institutions for People with Intellectual Disabilities in Taiwan: A Test of the Job Demand-Control-Support Model

    Science.gov (United States)

    Lin, Jin-Ding; Lee, Tzong-Nan; Yen, Chia-Feng; Loh, Ching-Hui; Hsu, Shang-Wei; Wu, Jia-Ling; Chu, Cordia M.

    2009-01-01

    Little is known about the job strain of staff working in disability institutions. This study investigated the staff's job strain profile and its determinants which included the worker characteristics and the psychosocial working environments in Taiwan. A cross-sectional study survey was carried out among 1243 workers by means of a self-answered…

  10. A Framework for Assessing Soil Moisture Deficit and Crop Water Stress at Multiple Space and Time Scales Under Climate Change Scenarios Using Model Platform, Satellite Remote Sensing, and Decision Support System

    KAUST Repository

    Mohanty, Binayak P.

    2016-11-03

    .g., crop rotation, soil modification, irrigation scheduling, better irrigation method/efficiency, water allocation, etc.) for risk reduction at field, county, state, region, and national scale using a web-based Decision Support System. This ongoing research provides a unifying global platform for forecasting several lagging indices for root zone soil moisture status as aridity index (AI), soil moisture deficit index (SMDI), and crop water stress index (CWSI) at the field, county, state, and regional scale on weekly, biweekly, monthly, and seasonal time scales by using various satellite and LDAS simulated data. Using available historical data, our approach is tested in various hydroclimatic regions (Great Plains, Midwest, West, Northeast, Southeast, and Southwest) across the USA. These indices form the basis for developing efficient management Decision Support Systems (DSS) for agricultural drought risk reduction and mitigation/adaption under the evolving climatic scenarios.

  11. AN OPEN AND VISUALIZED PLATFORM OF TECHNIQUE SUPPORT SYSTEM FOR ELECTRICITY MARKET%电力市场技术支持系统的开放式可视化管理平台

    Institute of Scientific and Technical Information of China (English)

    夏清; 康重庆; 沈瑜; 孙明; 刘明海; 周安石

    2001-01-01

    By introducing the concept of open software into geographic information system (GIS), a visualized management platform for electricity market is designed and developed. Graphic modeling, in which the graphic symbols express the mathematical models of power facilities, is firstly realized. Then an automatic network topology analysis function based on the geographic background is designed. By selecting commercial database as the information channel for data exchanging between GIS and application software, the platform is efficiently improved in its flexibility and reliability. Any application software can control all the actions of the components on a GIS figure by simply reading and writing the control-table. It opens the door for GIS to exchange data with the third-party software so that it has prosperous prospect in technique support system for electricity market.   This project is supported by National Key Basic Research Special Fund of China (No. G1998020311).%将开放式软件概念引入地理信息系统(GIS)之中,提出并初步实现了面向电力市场的开放式可视化管理平台。实现了电力元件的图形化建模和网络拓扑自动分析;选用数据库作为外界应用与该平台进行信息交互的媒介,使其在开放性、可靠性等方面有明显优势。外部应用只需通过读写刷新表即可操纵GIS图元的各种动作。这种开放平台可以方便地实现GIS与外部应用的数据交换,在电力市场技术支持系统中有着广阔的应用前景。

  12. Energy Tracking Software Platform

    Energy Technology Data Exchange (ETDEWEB)

    Ryan Davis; Nathan Bird; Rebecca Birx; Hal Knowles

    2011-04-04

    Acceleration has created an interactive energy tracking and visualization platform that supports decreasing electric, water, and gas usage. Homeowners have access to tools that allow them to gauge their use and track progress toward a smaller energy footprint. Real estate agents have access to consumption data, allowing for sharing a comparison with potential home buyers. Home builders have the opportunity to compare their neighborhood's energy efficiency with competitors. Home energy raters have a tool for gauging the progress of their clients after efficiency changes. And, social groups are able to help encourage members to reduce their energy bills and help their environment. EnergyIT.com is the business umbrella for all energy tracking solutions and is designed to provide information about our energy tracking software and promote sales. CompareAndConserve.com (Gainesville-Green.com) helps homeowners conserve energy through education and competition. ToolsForTenants.com helps renters factor energy usage into their housing decisions.

  13. ITS Platform North Denmark

    DEFF Research Database (Denmark)

    Lahrmann, Harry; Agerholm, Niels; Juhl, Jens

    2012-01-01

    This paper presents the project entitled “ITS Platform North Denmark” which is used as a test platform for Intelligent Transportation System (ITS) solutions. The platform consists of a newly developed GNSS/GPRS On Board Unit (OBU) to be installed in 500 cars, a backend server and a specially...... designed digital road map for ITS applications. The platform is freely accessible, which means that third party applications could be run on the platform. It is estimated that using this platform enables the ITS applications to be developed for 20% of the normal cost, hence third party are invited to test...... their applications in this platform. This paper presents the platform’s potentials and explains a series of test applications which are under development on it. Moreover, a number of new projects planned for the platform are demonstrated....

  14. ICT platform for support AC circuits study

    OpenAIRE

    Moisés Luis San Martín Ojeda; Eduardo Pedro Parra Gonzalo; Moisés Blanco Caballero; Alberto Sánchez Lite; Jose Andrés Serrano Sanz; Maria Isabel Jiménez Gómez; Manuel García García

    2014-01-01

    [EN] The software used for making educational tools allows analyze the engineering phenomena in a more complete and explained way, by means of simulation and experimentation. It is necessary to know the equations about the behaviour of the object under study for the generation of these tools, and to solve them through the right software, obtaining the output values from the input values. With this software it is possible to realize new studies only modifying the parameters of the ...

  15. CCSC Training: Small Platform Supports Great Dreams

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    The training center of China Classification Society Quality Assurance Corporation was having its training course of occupational health and safetymanagement system on Apr. 25th. Fu Diandong, the deputy director of CCSC sales department was having a heated communication with internal auditors coming from various industries in China. The training on new version API Q1 for internal auditors was also in full swing in the room next door. It was said that the training was in its second day.

  16. Mobile platform security

    CERN Document Server

    Asokan, N; Dmitrienko, Alexandra

    2013-01-01

    Recently, mobile security has garnered considerable interest in both the research community and industry due to the popularity of smartphones. The current smartphone platforms are open systems that allow application development, also for malicious parties. To protect the mobile device, its user, and other mobile ecosystem stakeholders such as network operators, application execution is controlled by a platform security architecture. This book explores how such mobile platform security architectures work. We present a generic model for mobile platform security architectures: the model illustrat

  17. Temperature profiles from mechanical bathythermograph (MBT) casts from the USS BELMONT and Other Platforms from Ocean Weather S (OWS-S) in the North Atlantic Ocean and other locations in support of the Fleet Observations of Oceanographic Data (FLOOD) project from 14 October 1961 to 15 February 1967 (NODC Accession 6900324)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — MBT data were collected from the USS BELMONT and Other Platforms within a 1-mile radius of Ocean Weather Station S (3210N 06430W) and in transit in support of the...

  18. Self-management support using an Internet-linked tablet computer (the EDGE platform)-based intervention in chronic obstructive pulmonary disease: protocol for the EDGE-COPD randomised controlled trial.

    Science.gov (United States)

    Farmer, Andrew; Toms, Christy; Hardinge, Maxine; Williams, Veronika; Rutter, Heather; Tarassenko, Lionel

    2014-01-08

    The potential for telehealth-based interventions to provide remote support, education and improve self-management for long-term conditions is increasingly recognised. This trial aims to determine whether an intervention delivered through an easy-to-use tablet computer can improve the quality of life of patients with chronic obstructive pulmonary disease (COPD) by providing personalised self-management information and education. The EDGE (sElf management anD support proGrammE) for COPD is a multicentre, randomised controlled trial designed to assess the efficacy of an Internet-linked tablet computer-based intervention (the EDGE platform) in improving quality of life in patients with moderate to very severe COPD compared with usual care. Eligible patients are randomly allocated to receive the tablet computer-based intervention or usual care in a 2:1 ratio using a web-based randomisation system. Participants are recruited from respiratory outpatient clinics and pulmonary rehabilitation courses as well as from those recently discharged from hospital with a COPD-related admission and from primary care clinics. Participants allocated to the tablet computer-based intervention complete a daily symptom diary and record clinical symptoms using a Bluetooth-linked pulse oximeter. Participants allocated to receive usual care are provided with all the information given to those allocated to the intervention but without the use of the tablet computer or the facility to monitor their symptoms or physiological variables. The primary outcome of quality of life is measured using the St George's Respiratory Questionnaire for COPD patients (SGRQ-C) baseline, 6 and 12 months. Secondary outcome measures are recorded at these intervals in addition to 3 months. The Research Ethics Committee for Berkshire-South Central has provided ethical approval for the conduct of the study in the recruiting regions. The results of the study will be disseminated through peer review publications and

  19. A Platform for Spreadsheet Composition

    CERN Document Server

    Baglietto, Pierpaolo; Mangiante, Simone; Maresca, Massimo; Parodi, Andrea; Stecca, Michele

    2011-01-01

    A huge amount of data is everyday managed in large organizations in many critical business sectors with the support of spreadsheet applications. The process of elaborating spreadsheet data is often performed in a distributed, collaborative way, where many actors enter data belonging to their local business domain to contribute to a global business view. The manual fusion of such data may lead to errors in copy-paste operations, loss of alignment and coherency due to multiple spreadsheet copies in circulation, as well as loss of data due to broken cross-spreadsheet links. In this paper we describe a methodology, based on a Spreadsheet Composition Platform, which greatly reduces these risks. The proposed platform seamlessly integrates the distributed spreadsheet elaboration, supports the commonly known spreadsheet tools for data processing and helps organizations to adopt a more controlled and secure environment for data fusion.

  20. Continuous Platform Development

    DEFF Research Database (Denmark)

    Nielsen, Ole Fiil

    low risks and investments but also with relatively fuzzy results. When looking for new platform projects, it is important to make sure that the company and market is ready for the introduction of platforms, and to make sure that people from marketing and sales, product development, and downstream......, but continuous product family evolution challenges this strategy. The concept of continuous platform development is based on the fact that platform development should not be a one-time experience but rather an ongoing process of developing new platforms and updating existing ones, so that product family...

  1. A Comparative Study on Hardware Platforms for Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    Thang Vu Chien

    2012-01-01

    Full Text Available Recently, Wireless Sensor Networks (WSNs attract a great deal of research attention, and are envisioned to support a variety of applications, including building monitoring, environment control, wild-life habitat monitoring, forest fire detection, industry automation, military, security, and health-care. Over the years, we have seen a variety of hardware platforms for WSNs to facilitate developing WSN applications. In this paper, we provide a comprehensive review of existing hardware platforms for WSNs. We first present the hardware architecture of a wireless sensor node. We then survey the major hardware platforms for WSNs and present a comparison of these hardware platforms. Finally we present some recommendations from the perspectives of hardware platform developers and hardware platform users. The authors hope that making information about existing hardware platforms will assist researchers working in this area to appreciate the diversity of platforms available to them and to help them select the most appropriate platform for their purposes.

  2. Cross-Platform Technologies

    Directory of Open Access Journals (Sweden)

    Maria Cristina ENACHE

    2017-04-01

    Full Text Available Cross-platform - a concept becoming increasingly used in recent years especially in the development of mobile apps, but this consistently over time and in the development of conventional desktop applications. The notion of cross-platform software (multi-platform or platform-independent refers to a software application that can run on more than one operating system or computing architecture. Thus, a cross-platform application can operate independent of software or hardware platform on which it is execute. As a generic definition presents a wide range of meanings for purposes of this paper we individualize this definition as follows: we will reduce the horizon of meaning and we use functionally following definition: a cross-platform application is a software application that can run on more than one operating system (desktop or mobile identical or in a similar way.

  3. Platform evolution studies

    Science.gov (United States)

    Walton, Barbara A.

    1990-01-01

    The polar orbiting platform (POP), being developed by the Work Package 3 (WP3) Project at the Goddard Space Flight Center, will play a key role in the NASA Leadership Initiative, Mission to Planet Earth (MPE). It becomes, with the addition of payloads, an Earth observation satellite observatory. Mission to Planet Earth also has geostationary platforms (GEOP) as part of its global observational system. A study was begun in March 1988 to assess the applicability of the POP orbital replacement units (ORUs) for a geostationary Earth observing mission. Two test cases, representative of MPE payloads, were studied. Case A was used to emphasize the GEOP configuration and design; it used a Titan/Centaur to achieve orbit. Case B, considered to be much further in the future, included some assembly at the Space Station Freedom manned base and use of an orbital transfer vehicle to achieve orbit; requirements on the manned base to support such a mission were emphasized. The study found the POP systems more than adequate to meet GEOP requirements. Two types of changes were required for the POP ORUs: (1) modification to use only one surface for heat rejection; for the battery ORU, this meant 'opening up' the ORU to retain the radiator area with a corresponding decrease in depth; and (2) deletion of equipment not needed. The Case A configuration was shown to be within the planned capability of the Titan IV/Centaur. Assembly requirements were included for the Case B configuration, which is driven by the large microwave antennas of two of the payloads. The final review was April 19, 1989.

  4. Genome sequence of Kosmotoga olearia strain TBF 19.5.1, a thermophilic bacterium with a wide growth temperature range, isolated from the Troll B oil platform in the North Sea.

    Science.gov (United States)

    Swithers, Kristen S; DiPippo, Jonathan L; Bruce, David C; Detter, Christopher; Tapia, Roxanne; Han, Shunsheng; Goodwin, Lynne A; Han, James; Woyke, Tanja; Pitluck, Sam; Pennacchio, Len; Nolan, Matthew; Mikhailova, Natalia; Land, Miriam L; Nesbø, Camilla L; Gogarten, J Peter; Noll, Kenneth M

    2011-10-01

    Kosmotoga olearia strain TBF 19.5.1 is a member of the Thermotogales that grows best at 65°C and very well even at 37°C. Information about this organism is important for understanding the evolution of mesophiles from thermophiles. Its genome sequence reveals extensive gene gains and a large content of mobile genetic elements. It also contains putative hydrogenase genes that have no homologs in the other member of the Thermotogales.

  5. Genome Sequence of Kosmotoga olearia Strain TBF 19.5.1, a Thermophilic Bacterium with a Wide Growth Temperature Range, Isolated from the Troll B Oil Platform in the North Sea

    Energy Technology Data Exchange (ETDEWEB)

    Swithers, Kristen S [University of Connecticut, Storrs; DiPippo, Jonathan L [University of Connecticut, Storrs; Bruce, David [Los Alamos National Laboratory (LANL); Detter, J. Chris [U.S. Department of Energy, Joint Genome Institute; Tapia, Roxanne [Los Alamos National Laboratory (LANL); Han, Cliff [Los Alamos National Laboratory (LANL); Goodwin, Lynne A. [Los Alamos National Laboratory (LANL); Han, James [U.S. Department of Energy, Joint Genome Institute; Woyke, Tanja [U.S. Department of Energy, Joint Genome Institute; Pitluck, Sam [U.S. Department of Energy, Joint Genome Institute; Pennacchio, Len [U.S. Department of Energy, Joint Genome Institute; Nolan, Matt [U.S. Department of Energy, Joint Genome Institute; Land, Miriam L [ORNL; Nesbo, Camilla [University of Oslo, Norway; Gogarten, Peter [University of Connecticut, Storrs; Noll, Kenneth M [University of Connecticut, Storrs

    2011-01-01

    Kosmotoga olearia strain TBF 19.5.1 is a member of the Thermotogales that grows best at 65 degrees C and very well even at 37 degrees C. Information about this organism is important for understanding the evolution of mesophiles from thermophiles. Its genome sequence reveals extensive gene gains and a large content of mobile genetic elements. It also contains putative hydrogenase genes that have no homologs in the other member of the Thermotogales.

  6. City-as-a-Platform: The Rise of Participatory Innovation Platforms in Finnish Cities

    Directory of Open Access Journals (Sweden)

    Ari-Veikko Anttiroiko

    2016-09-01

    Full Text Available This article discusses the idea of city as a platform. The analysis focuses on the forms and implications of citizen involvement in publicly-supported participatory innovation platforms that facilitate urban economic development in the welfare society context. The discussion opens with a review of the smart city discourse, which in the context of economic development policy translates into cities’ need to support innovativeness by creating smart environments. Participatory innovation platform is a prime example of such an environment. The empirical section discusses three cases, those of the Finnish cities of Helsinki, Tampere, and Oulu. The analysis shows that platformization in the first half of the 2010s became a strategic focal area supported by national and EU programs. Platforms are used to support both urban revitalization and economic development, of which the former is based on representative and the latter on instrumental modes of participation. Platforms are well integrated with city governments, even though they vary greatly in terms of organizational forms and scopes. Democratic culture, welfarism, and redistributive policy provide contextual support for platformization by strengthening social inclusion, taming the growth machine, and easing the tensions between pro-growth and anti-growth coalitions.

  7. The Design of Support Platform for Experimental Teaching Based on the Project and Case%基于项目案例的实验教学支撑平台的设计

    Institute of Scientific and Technical Information of China (English)

    孔彦杰; 郭明超; 马浚

    2012-01-01

    The paper analyzes the current situation of experimental teaching of computer application and software engineering in colleges and universities,takes solid foundation,scientific assessment,standard design,and stimulating innovation as the aim,puts forward the ideas and methods of constructing support platform for experimental teaching of software curriculum;completes the design of five subsystems including synchronous experiment,assessment test,case appreciation,team cooperation,and independent innovation,etc.According to the inherent connection among professional curriculum,taken the successful case of engineering practice as the organization link,we present students the whole process of developing software,and stress on practice,focus on accumulation,and stimulate innovation,and then gradually realize the hierarchical development of successive students' learning process.%本文分析了高校计算机应用与软件工程方向实验教学的现状,以夯实基础、科学考核、规范设计、激励创新为宗旨,提出了创建软件课程实验教学支持平台的思想和实现方法;完成了同步实验、考核测试、案例欣赏、小组合作、自主创新等5个子系统的设计。依据专业课程之间固有的联系,以工程实践的成功案例为组织纽带,向学生展示软件开发的全过程,强调实践、重视积累、激励创新,逐步实现历届学生学习过程的层次型发展。

  8. Platform switching and bone platform switching.

    Science.gov (United States)

    Carinci, Francesco; Brunelli, Giorgio; Danza, Matteo

    2009-01-01

    Bone platform switching involves an inward bone ring in the coronal part of the implant that is in continuity with the alveolar bone crest. Bone platform switching is obtained by using a dental fixture with a reverse conical neck. A retrospective study was performed to evaluate the effectiveness of conventional vs reverse conical neck implants. In the period between May 2004 and November 2007, 86 patients (55 females and 31 males; median age, 53 years) were operated and 234 implants were inserted: 40 and 194 were conventional vs reverse conical neck implants, respectively. Kaplan-Meier algorithm and Cox regression were used to detect those variables associated with the clinical outcome. No differences in survival and success rates were detected between conventional vs reverse conical neck implants alone or in combination with any of the studied variables. Although bone platform switching leads to several advantages, no statistical difference in alveolar crest resorption is detected in comparison with reverse conical neck implants. We suppose that the proximity of the implant abutment junction to the alveolar crestal bone gives no protection against the microflora contained in the micrograph. Additional studies on larger series and a combination of platform switching and bone platform switching could lead to improved clinical outcomes.

  9. Meteorological, oceanographic, wave spectra, and other data from FIXED PLATFORMS from the North Atlantic Ocean and other locations in support of the Tropical Ocean Global Atmosphere (TOGA) project from 01 August 1987 to 27 August 1987 (NODC Accession 8700309)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Meteorological, oceanographic, wave spectra, and other data were collected from FIXED PLATFORMS in the North Atlantic and other locations. Data were collected by the...

  10. Current meter - direction and other data from FIXED PLATFORMS in support of the MESA PUGET SOUND/PSERP (MESA-PS) project from 03 September 1975 to 11 November 1975 (NODC Accession 7800018)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Current meter - direction and other data were collected from FIXED PLATFORMS from 03 September 1975 to 11 November 1975. Data were collected by the National Ocean...

  11. Meteorological, oceanographic, wave spectra, and other data from FIXED PLATFORMS from the North Atlantic Ocean and other locations in support of the Tropical Ocean Global Atmosphere (TOGA) project from 01 February 1986 to 21 February 1986 (NODC Accession 8600105)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Meteorological, oceanographic, wave spectra, and other data were collected from FIXED PLATFORMS in the North Atlantic Ocean and other locations. Data were collected...

  12. Meteorological, oceanographic, wave spectra, and other data from FIXED PLATFORMS from the North Atlantic Ocean and other locations in support of the Tropical Ocean Global Atmosphere (TOGA) project from 01 November 1086 to 04 November 1986 (NODC Accession 8600400)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Meteorological, oceanographic, wave spectra, and other data were collected from FIXED PLATFORMS in the North Atlantic and other locations. Data were collected by the...

  13. Meteorological, oceanographic, wave spectra, and other data from FIXED PLATFORMS from the North Atlantic Ocean and other locations in support of the Tropical Ocean Global Atmosphere (TOGA) project from 01 July 1986 to 31 July 1986 (NODC Accession 8600396)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Meteorological, oceanographic, wave spectra, and other data were collected from FIXED PLATFORMS in the North Atlantic and other locations. Data were collected by the...

  14. Meteorological, oceanographic, wave spectra, and other data from FIXED PLATFORMS from the North Atlantic Ocean and other locations in support of the Tropical Ocean Global Atmosphere (TOGA) project from 01 April 1988 to 29 April 1988 (NODC Accession 8800152)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Meteorological, oceanographic, wave spectra, and other data were collected from FIXED PLATFORMS in the North Atlantic and other locations. Data were collected by the...

  15. Meteorological, oceanographic, wave spectra, and other data from FIXED PLATFORMS from the North Atlantic Ocean and other locations in support of the Tropical Ocean Global Atmosphere (TOGA) project from 01 October 1986 to 16 October 1986 (NODC Accession 8600399)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Meteorological, oceanographic, wave spectra, and other data were collected from FIXED PLATFORMS in the North Atlantic and other locations. Data were collected by the...

  16. Meteorological, oceanographic, wave spectra, and other data from FIXED PLATFORMS from the North Atlantic Ocean and other locations in support of the Tropical Ocean Global Atmosphere (TOGA) project from 01 September 1986 to 18 September 1986 (NODC Accession 8600395)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Meteorological, oceanographic, wave spectra, and other data were collected from FIXED PLATFORMS in the North Atlantic and other locations. Data were collected by the...

  17. Meteorological, oceanographic, wave spectra, and other data from FIXED PLATFORMS from the North Atlantic Ocean and other locations in support of the Tropical Ocean Global Atmosphere (TOGA) project from 01 February 1988 to 25 February 1988 (NODC Accession 8800082)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Meteorological, oceanographic, wave spectra, and other data were collected from FIXED PLATFORMS in the North Atlantic and other locations. Data were collected by the...

  18. Meteorological, oceanographic, wave spectra, and other data from FIXED PLATFORMS from the North Atlantic Ocean and other locations in support of the Tropical Ocean Global Atmosphere (TOGA) project from 01 June 1986 to 28 June 1986 (NODC Accession 8600257)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Meteorological, oceanographic, wave spectra, and other data were collected from FIXED PLATFORMS. Data were collected by the National Data Buoy Center (NDBC) in...

  19. Current direction, marine toxic substances, and other data from current meters and grab casts from the GUSS III and other platforms in support of the Brine Disposal project from 20 October 1977 to 16 April 1979 (NODC Accession 8000029)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Current direction, marine toxic substances, and other data from were collected from current meters and grab casts from the GUSS III and other platforms from 20...

  20. Meteorological, oceanographic, wave spectra, and other data from FIXED PLATFORMS from the North Atlantic Ocean and other locations in support of the Tropical Ocean Global Atmosphere (TOGA) project from 01 May 1985 to 28 May 1985 (NODC Accession 8500301)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Meteorological, oceanographic, wave spectra, and other data were collected from FIXED PLATFORMS in the North Atlantic and other locations. Data were collected by the...

  1. Meteorological, oceanographic, wave spectra, and other data from FIXED PLATFORMS from the North Atlantic Ocean and other locations in support of the Tropical Ocean Global Atmosphere (TOGA) project from 01 August 1986 to 20 August 1986 (NODC Accession 8600361)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Meteorological, oceanographic, wave spectra, and other data were collected from FIXED PLATFORMS in the North Atlantic and other locations. Data were collected by the...

  2. Meteorological, oceanographic, wave spectra, and other data from FIXED PLATFORMS from the North Atlantic Ocean and other locations in support of the Tropical Ocean Global Atmosphere (TOGA) project from 01 December 1987 to 04 December 1987 (NODC Accession 8800023)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Meteorological, oceanographic, wave spectra, and other data were collected from FIXED PLATFORMS in the Atlantic Ocean and other locations. Data were collected by the...

  3. Meteorological, oceanographic, wave spectra, and other data from FIXED PLATFORMS from the North Atlantic Ocean and other locations in support of the Tropical Ocean Global Atmosphere (TOGA) project from 01 March 1986 to 26 March 1986 (NODC Accession 8600152)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Meteorological, oceanographic, wave spectra, and other data were collected from FIXED PLATFORMS in the North Atlantic Ocean and other locations. Data were collected...

  4. Meteorological, oceanographic, wave spectra, and other data from FIXED PLATFORMS from the North Atlantic Ocean and other locations in support of the Tropical Ocean Global Atmosphere (TOGA) project from 01 April 1986 to 14 April 1986 (NODC Accession 8600167)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Meteorological, oceanographic, wave spectra, and other data were collected from FIXED PLATFORMS. Data were collected by the National Data Buoy Center (NDBC) in...

  5. Meteorological, oceanographic, wave spectra, and other data from FIXED PLATFORMS from the North Atlantic Ocean and other locations in support of the Tropical Ocean Global Atmosphere (TOGA) project from 01 May 1988 to 27 May 1988 (NODC Accession 8800185)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Meteorological, oceanographic, wave spectra, and other data were collected from FIXED PLATFORMS in the North Atlantic and other locations. Data were collected by the...

  6. Meteorological, oceanographic, wave spectra, and other data from FIXED PLATFORMS from the North Atlantic Ocean and other locations in support of the Tropical Ocean Global Atmosphere (TOGA) project from 01 June 1987 to 19 June 1987 (NODC Accession 8700270)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Meteorological, oceanographic, wave spectra, and other data were collected from FIXED PLATFORMS in the North Atlantic Ocean and other locations. Data were collected...

  7. Meteorological, oceanographic, wave spectra, and other data from FIXED PLATFORMS from the North Atlantic Ocean and other locations in support of the Tropical Ocean Global Atmosphere (TOGA) project from 01 July 1987 to 21 July 1987 (NODC Accession 8700279)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Meteorological, oceanographic, wave spectra, and other data were collected from FIXED PLATFORMS in the North Atlantic and other locations. Data were collected by the...

  8. Meteorological, oceanographic, wave spectra, and other data from FIXED PLATFORMS from the North Atlantic Ocean and other locations in support of the Tropical Ocean Global Atmosphere (TOGA) project from 01 March 1988 to 29 March 1988 (NODC Accession 8800131)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Meteorological, oceanographic, wave spectra, and other data were collected from FIXED PLATFORMS in the North Atlantic and other locations. Data were collected by the...

  9. Meteorological, oceanographic, wave spectra, and other data from FIXED PLATFORMS from the North Atlantic Ocean and other locations in support of the Tropical Ocean Global Atmosphere (TOGA) project from 01 November 1987 to 05 November 1987 (NODC Accession 8800003)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Meteorological, oceanographic, wave spectra, and other data were collected from FIXED PLATFORMS in the North Atlantic and other locations. Data were collected by the...

  10. Meteorological, oceanographic, wave spectra, and other data from FIXED PLATFORMS from the North Atlantic Ocean and other locations in support of the Tropical Ocean Global Atmosphere (TOGA) project from 01 September 1987 to 13 September 1987 (NODC Accession 8700355)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Meteorological, oceanographic, wave spectra, and other data were collected from FIXED PLATFORMS in the North Atlantic and other locations.Data were collected by the...

  11. Meteorological, oceanographic, wave spectra, and other data from FIXED PLATFORMS from the North Atlantic Ocean and other locations in support of the Tropical Ocean Global Atmosphere (TOGA) project from 01 October 1987 to 28 October 1987 (NODC Accession 8700380)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Meteorological, oceanographic, wave spectra, and other data were collected from FIXED PLATFORMS in the North Atlantic and other locations. Data were collected by the...

  12. CTD, current meter, meteorological buoy, and bottle data from the Gulf of Mexico from the ALPHA HELIX and other platforms in support of LATEX A from 18 March 1993 to 23 September 1993 (NODC Accession 9400149)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — CTD, current meter, meteorological buoy, and bottle data were collected from the Gulf of Mexico from the ALPHA HELIX and other platforms. Data were collected by...

  13. Meteorological, oceanographic, wave spectra, and other data from FIXED PLATFORMS from the North Atlantic Ocean and other locations in support of the Tropical Ocean Global Atmosphere (TOGA) project from 01 May 1986 to 30 May 1986 (NODC Accession 8600203)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Meteorological, oceanographic, wave spectra, and other data were collected from FIXED PLATFORMS in the North Atlantic Ocean and other locations. Data were collected...

  14. Meteorological, oceanographic, wave spectra, and other data from FIXED PLATFORMS from the North Atlantic Ocean and other locations in support of the Tropical Ocean Global Atmosphere (TOGA) project from 01 April 1985 to 16 April 1985 (NODC Accession 8500300)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Meteorological, oceanographic, wave spectra, and other data were collected from FIXED PLATFORMS in the North Atlantic and other locations. Data were collected by the...

  15. Meteorological, oceanographic, wave spectra, and other data from FIXED PLATFORMS from the North Atlantic Ocean and other locations in support of the Tropical Ocean Global Atmosphere (TOGA) project from 01 March 1985 to 28 March 1985 (NODC Accession 8600039)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Meteorological, oceanographic, wave spectra, and other data were collected from FIXED PLATFORMS in the North Atlantic Ocean and other locations. Data were collected...

  16. Meteorological, oceanographic, wave spectra, and other data from FIXED PLATFORM in the North Atlantic Ocean and other locations in support of the Tropical Ocean Global Atmosphere (TOGA) project from 01 January 1985 to 26 January 1985 (NODC Accession 8500299)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Meteorological, oceanographic, wave spectra, and other data were collected from FIXED PLATFORMS in the North Atlantic and other locations. Data were collected by the...

  17. Meteorological, oceanographic, wave spectra, and other data from FIXED PLATFORMS in support of the Tropical Ocean Global Atmosphere (TOGA) project from 01 January 1985 10 January 1985 (NODC Accession 8600340)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Meteorological, oceanographic, wave spectra, and other data were collected from FIXED PLATFORMS in the North Atlantic Ocean and other locations. Data were collected...

  18. Meteorological, oceanographic, wave spectra, and other data from FIXED PLATFORMS from the North Atlantic Ocean and other locations in support of the Tropical Ocean Global Atmosphere (TOGA) project from 01 December 1986 to 16 December 1986 (NODC Accession 8700061)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Meteorological, oceanographic, wave spectra, and other data were collected from FIXED PLATFORMS in the North Atlantic and other locations.Data were collected by the...

  19. Meteorological, oceanographic, wave spectra, and other data from FIXED PLATFORMS from the North Atlantic Ocean and other locations in support of the Tropical Ocean Global Atmosphere (TOGA) project from 01 March 1987 to 21 March 1987 (NODC Accession 8700176)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Meteorological, oceanographic, wave spectra, and other data were collected from FIXED PLATFORMS in the North Atlantic and other locations. Data were collected by the...

  20. Meteorological, oceanographic, wave spectra, and other data from FIXED PLATFORMS from the North Atlantic Ocean and other locations in support of the Tropical Ocean Global Atmosphere (TOGA) project from 01 October 1985 to 25 October 1985 (NODC Accession 8500306)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Meteorological, oceanographic, wave spectra, and other data were collected from FIXED PLATFORMS on the North Atlantic Ocean and other locations. Data were collected...

  1. Meteorological, oceanographic, wave spectra, and other data from FIXED PLATFORMS from the North Atlantic Ocean and other locations in support of the Tropical Ocean Global Atmosphere (TOGA) project from 01 June 1985 to 27 June 1985 (NODC Accession 8500302)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Meteorological, oceanographic, wave spectra, and other data were collected from FIXED PLATFORMS in the North Atlantic Ocean and other locations. Data were collected...

  2. Current meter components and other data from FIXED PLATFORMS in support of the Processes and Resources of the Bering Sea Shelf (PROBES) project from 27 April 1977 to 01 November 1978 (NODC Accession 8400221)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Current meter components data were collected from FIXED PLATFORMS from 22 February 1992 to 18 February 1993. Data were collected by the University of Alaska -...

  3. Current meter components and other data from FIXED PLATFORMS in support of the Physical Oceanography Field Program Offshore North Carolina from 22 February 1992 to 18 February 1993 (NODC Accession 9300089)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Current meter components data were collected from FIXED PLATFORMS from 22 February 1992 to 18 February 1993. Data were collected by the Science Applications, Inc....

  4. Pressure gauge and CTD data from ICE ISLANDS and other platforms from the Beaufort and Chukchi Seas in support of the Outer Continental Shelf Environmental Assessment Program (OCSEAP) from 25 July 1982 to 08 March 1984 (NODC Accession 8500129)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Pressure gauge and CTD data were collected from the ICE ISLANDS and other platforms in the Beaufort and Chukchi Seas from 25 July 1982 to 08 March 1984. Data were...

  5. Current meter components and other data from fixed platforms from the Straits of Florida in support of the Southeast Florida and Caribbean Recruitment Program (SEFCAR) from 08 April 1989 to 21 November 1994 (NODC Accession 9600059)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Current meter components data were collected from fixed platforms in the Straits of Florida from 08 April 1989 to 21 November 1994. Data were collected by the...

  6. Current and other data from meters attached to FIXED PLATFORMS in the coastal waters of Florida in support of the Subtropical Atlantic Climate Study 3 (STACS) from 10 November 1980 to 07 June 1983 (NODC Accession 8800120)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Current and other data from meters attached to FIXED PLATFORMS in the coastal waters of Florida. Data were collected by University of Miami; Rosenstiel School of...

  7. Current and other data from meters attached to FIXED PLATFORMS in the coastal waters of Florida in support of the Subtropical Atlantic Climate Study 4 (STACS) from 08 June 1983 to 13 December 1983 (NODC Accession 8700019)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Current and other data from meters attached to FIXED PLATFORMS in the coastal waters of Florida. Data were collected by University of Miami; Rosenstiel School of...

  8. Current and other data from meters attached to FIXED PLATFORMS in the coastal waters of Florida in support of the Subtropical Atlantic Climate Study 6 (STACS) from 19 June 1984 to 27 March 1987 (NODC Accession 8900060)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Current and other data from meters attached to FIXED PLATFORMS in the coastal waters of Florida. Data were collected by University of Miami; Rosenstiel School of...

  9. Current meter - direction and other data from FIXED PLATFORMS in support of the MESA New York Bight (MESA-NYB) project from 30 November 1976 to 25 April 1977 (NODC Accession 7700712)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Current meter - direction and other data were collected from FIXED PLATFORMS from 30 November 1976 to 25 April 1977. Data were collected by the National Ocean...

  10. Current meter - direction and other data from FIXED PLATFORMS in support of the MESA New York Bight (MESA-NYB) project from 15 December 1977 to 19 March 1978 (NODC Accession 7900293)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Current meter - direction and other data were collected from FIXED PLATFORMS from 15 December 1977 to 19 March 1978. Data were collected by Dames and Moore, Inc. -...

  11. Current meter - direction and other data from FIXED PLATFORMS in support of the MESA New York Bight (MESA-NYB) project from 25 September 1978 to 11 July 1979 (NODC Accession 7900330)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Current meter - direction and other data were collected from FIXED PLATFORMS from 25 September 1978 to 11 July 1979. Data were collected by the National Ocean...

  12. Current meter - direction and other data from FIXED PLATFORMS in support of the MESA New York Bight (MESA-NYB) project from 03 April 1979 to 11 July 1979 (NODC Accession 8000011)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Current meter - direction and other data were collected from FIXED PLATFORMS from 03 April 1979 to 11 July 1979. Data were collected by the National Ocean Service...

  13. Current meter - direction and other data from FIXED PLATFORMS in support of the MESA New York Bight (MESA-NYB) project from 27 October 1975 to 14 August 1976 (NODC Accession 7700083)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Current meter - direction and other data were collected from FIXED PLATFORMS from 27 October 1975 to 14 August 1976. Data were collected by the National Ocean...

  14. Current meter - direction and other data from FIXED PLATFORMS in support of the MESA PUGET SOUND/PSERP (MESA-PS) project from 26 September 1974 to 14 April 1975 (NODC Accession 7601210)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Current meter - direction and other data were collected from FIXED PLATFORMS from 26 September 1974 to 14 April 1975. Data were collected by the National Ocean...

  15. Current meter - direction and other data from FIXED PLATFORMS in support of the MESA New York Bight (MESA-NYB) project from 25 July 1978 to 16 October 1978 (NODC Accession 7900246)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Current meter - direction and other data were collected from FIXED PLATFORMS from 25 July 1978 to 16 October 1978. Data were collected by the National Ocean Service...

  16. Current meter - direction and other data from FIXED PLATFORMS in support of the MESA New York Bight (MESA-NYB) project from 03 November 1977 to 31 January 1978 (NODC Accession 7800572)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Current meter - direction and other data were collected from FIXED PLATFORMS from 03 November 1977 to 31 January 1978. Data were collected by the National Ocean...

  17. Current meter - direction and other data from FIXED PLATFORMS in support of the Southern Coastal Plains Expedition (SCOPE) from 13 February 1972 to 24 April 1973 (NODC Accession 7500583)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Current meter - direction and other data were collected from FIXED PLATFORMS from 13 February 1972 to 24 April 1973. Data were collected by the National Ocean...

  18. Current meter - direction and other data from FIXED PLATFORMS in support of the MESA New York Bight (MESA-NYB) project from 30 January 1978 to 27 July 1978 (NODC Accession 7900077)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Current meter - direction and other data were collected from FIXED PLATFORMS from 30 January 1978 to 27 July 1978. Data were collected by the National Ocean Service...

  19. Current meter - direction and other data from FIXED PLATFORMS in support of the MESA New York Bight (MESA-NYB) project from 01 April 1974 to 25 September 1974 (NODC Accession 7700207)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Current meter - direction and other data were collected from FIXED PLATFORMS from 01 April 1974 to 25 September 1974. Data were collected by the National Ocean...

  20. Current meter - direction and other data from FIXED PLATFORMS in support of the MESA New York Bight (MESA-NYB) project from 13 August 1976 to 01 December 1976 (NODC Accession 7700640)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Current meter - direction and other data were collected from FIXED PLATFORMS from 13 August 1976 to 01 December 1976. Data were collected by the National Ocean...

  1. Current meter - direction and other data from FIXED PLATFORMS in support of the MESA New York Bight (MESA-NYB) project from 24 February 1975 to 01 May 1975 (NODC Accession 7700554)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Current meter - direction and other data were collected from FIXED PLATFORMS from 24 February 1975 to 01 May 1975. Data were collected by the National Ocean Service...

  2. Meteorological, oceanographic, wave spectra, and other data from FIXED PLATFORMS from the North Atlantic Ocean and other locations in support of the Tropical Ocean Global Atmosphere (TOGA) project from 01 July 1985 to 30 July 1985 (NODC Accession 8500303)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Meteorological, oceanographic, wave spectra, and other data were collected from FIXED PLATFORMS in the North Atlantic Ocean. Data were collected by the National Data...

  3. Meteorological, oceanographic, wave spectra, and other data from FIXED PLATFORMS from the North Atlantic Ocean and other locations in support of the Tropical Ocean Global Atmosphere (TOGA) project from 01 November 1985 to 05 November 1985 (NODC Accession 8500307)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Meteorological, oceanographic, wave spectra, and other data were collected from FIXED PLATFORMS in the North Atlantic Ocean and other locations. Data were collected...

  4. Physical, current, and other data from CTD and current meters from FIXED PLATFORMS in the Bering Sea in support of the Fisheries-Oceanography Coordinated Investigations (FOCI) project from 25 February 1998 to 10 October 2001 (NODC Accession 0000665)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Physical, current, and other data from CTD and current meters from FIXED PLATFORMS in the Bering Sea from 25 February 1998 to 10 October 2001. Data were collected by...

  5. Current meter - direction and other data from FIXED PLATFORMS in support of the MESA New York Bight (MESA-NYB) project from 17 October 1974 to 20 November 1975 (NODC Accession 7700291)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Current meter - direction and other data were collected from FIXED PLATFORMS from 17 October 1974 to 20 November 1975. Data were collected by the National Ocean...

  6. Current meter components and other data from FIXED PLATFORMS from NW Pacific (limit-180) in support of the Emperor Seamount Experiment from 28 June 1982 to 01 November 1983 (NODC Accession 8500287)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Current meter components data were collected from FIXED PLATFORMS in the NW Pacific (limit-180) from 28 June 1982 to 01 November 1983 . Data were collected by the...

  7. Platform development supportedby gaming

    DEFF Research Database (Denmark)

    Mikkola, Juliana Hsuan; Hansen, Poul H. Kyvsgård

    2007-01-01

    The challenge of implementing industrial platforms in practice can be described as a configuration problem caused by high number of variables, which often have contradictory influences on the total performance of the firm. Consequently, the specific platform decisions become extremely complex......, possibly increasing the strategic risks for the firm. This paper reports preliminary findings on platform management process at LEGO, a Danish toy company.  Specifically, we report the process of applying games combined with simulations and workshops in the platform development. We also propose a framework......, based on the portfolio management thinking, to measure the degree of modularity embedded in a given platform and to what extent it is aligned with other platforms....

  8. The Ssr protein (T1E_1405) from Pseudomonas putida DOT-T1E enables oligonucleotide-based recombineering in platform strain P. putida EM42

    DEFF Research Database (Denmark)

    Aparicio, Tomás; Ingemann Jensen, Sheila; Nielsen, Alex Toftgaard

    2016-01-01

    of reference strain KT2440) is still a time-consuming endeavor. In this work we have investigated the in vivo activity of the Ssr protein encoded by the open reading frame T1E_1405 from Pseudomonas putida DOT-T1E, a plausible functional homologue of the β protein of the Red recombination system of λ phage...... of Escherichia coli. A test based on the phenotypes of pyrF mutants of P. putida (the yeast’s URA3 ortholog) was developed for quantifying the ability of Ssr to promote invasion of the genomic DNA replication fork by synthetic oligonucleotides. The efficiency of the process was measured by monitoring...

  9. DFH-3 Satellite Platform

    Institute of Scientific and Technical Information of China (English)

    RenShufang

    2005-01-01

    The DFH-3 satellite platform is designed and developed by China Academy of Space Technology (CAST). It is a medium capability communications satellite platform. The platform adopts threeaxis attitude stabilization control system, having solar array output power of 1.7kW by the end of its design lifetime of 8 years. Its mass is 2100kg with payload capacity of 220kg.

  10. Product Platform Replacements

    DEFF Research Database (Denmark)

    Sköld, Martin; Karlsson, Christer

    2012-01-01

    Purpose – It is argued in this article that too little is known about product platforms and how to deal with them from a manager's point of view. Specifically, little information exists regarding when old established platforms are replaced by new generations in R&D and production environments...... originality and value is achieved by focusing on product platform replacements believed to represent a growing management challenge....

  11. Flexible optical chemical sensor platform for BTX

    OpenAIRE

    Arias Espinoza, Juan Diego; Sazhnikov, Viacheslav; Sabik, Sami; Ionov, Dmitriy; Smits, Edsger; Kalathimekkad, Sandeep; Van Steenberge, Geert; Alfimov, Michail; Posniak, Malgorzata; Schoo, Herman

    2012-01-01

    An in-plane flexible sensor platform for BTX detection was developed using low-cost patterning techniques and foil-based optical components. The platform was produced by a combination of laser patterning, inkjet printing and capillary filling. Key optical components such as lightguides, opticalcladding layers and metallic interconnections were realized on low cost substrates such as paper and PET. The sensing mechanism is based on the change in fluorescence spectra of a reporter dye, supporte...

  12. The Creative Platform

    DEFF Research Database (Denmark)

    Byrge, Christian; Hansen, Søren

    This book is about introducing more creativity into general educational courses and cross-disciplinary activities. It is directed toward teachers at all levels in the educational system, but the Creative Platform is a general model, and thus the creative process will fundamentally be the same...... whether you consider thirdgrade teaching, human-resource development, or radical new thinking in product development in a company. The Creative Platform was developed at Aalborg University through a series of research-and-development activities in collaboration with educational institutions and private...... you can use in your work with the Creative Platform. This book is intended as an introduction on how to use the Creative Platform....

  13. Omnidirectional holonomic platforms

    Energy Technology Data Exchange (ETDEWEB)

    Pin, F.G.; Killough, S.M.

    1994-06-01

    This paper presents the concepts for a new family of wheeled platforms which feature full omnidirectionality with simultaneous and independently controlled rotational and translational motion capabilities. The authors first present the orthogonal-wheels concept and the two major wheel assemblies on which these platforms are based. They then describe how a combination of these assemblies with appropriate control can be used to generate an omnidirectional capability for mobile robot platforms. The design and control of two prototype platforms are then presented and their respective characteristics with respect to rotational and translational motion control are discussed.

  14. Advanced offshore oil platforms

    Energy Technology Data Exchange (ETDEWEB)

    Ellers, F.S.

    1982-04-01

    Four innovative offshore platforms that are designed to withstand 100-foot waves in waters 600-feet deep are described. These platforms are: (1) Stratfjord B Concrete Gravity-Base Platform; (2) Magnus Steel-Template-Jacket Platform; (3) Hutton Tension-Leg Platform; and (4) Block 280 Guyed Tower. The Statfjord B platform, designed in Norway, rests on four massive concrete columns with storage tanks at the base. It depends solely on its own mass for stability. The Magnus platform, designed by the British, is the heaviest offshore platform yet fabricated, weighing 41,000 tons. Two of the platform's four legs will incorporate flotation chambers so that the structure can be floated to its site in the North Sea. The Hutton structure, also designed in England, will consist of a buoyant hull tethered to the sea floor by slender steel tubes at its four corners. The first platform of its type, the Hutton structure is also destined for the North Sea. The US designed Block 280 guyed tower is designed for service in the Gulf of Mexico in water 1000 feet deep. It will be pinned to the sea floor by a spokelike array of 20 steel cables, each one more than 3000 feet long. The tower and its guys will weigh 43,000 tons, slightly more than the Magnus steel-template jacket and more than four time as much as the Eiffel Tower. At a cost of approximately $2.6 billion, the Magnus is the most expensive offshore platform to date. The Statfjord B was put into production in 1982. The Magnus is scheduled for oil production in 1983. The Hutton and the Block 280 will both be producing in 1984. (JMT)

  15. YARP: Yet Another Robot Platform

    Directory of Open Access Journals (Sweden)

    Lorenzo Natale

    2008-11-01

    Full Text Available We describe YARP, Yet Another Robot Platform, an open-source project that encapsulates lessons from our experience in building humanoid robots. The goal of YARP is to minimize the effort devoted to infrastructure-level software development by facilitating code reuse, modularity and so maximize research-level development and collaboration. Humanoid robotics is a "bleeding edge" field of research, with constant flux in sensors, actuators, and processors. Code reuse and maintenance is therefore a significant challenge. We describe the main problems we faced and the solutions we adopted. In short, the main features of YARP include support for inter-process communication, image processing as well as a class hierarchy to ease code reuse across different hardware platforms. YARP is currently used and tested on Windows, Linux and QNX6 which are common operating systems used in robotics.

  16. Multithreading platform for multimedia applications

    Science.gov (United States)

    Koster, Rainer; Kramp, Thorsten

    2000-12-01

    Complex multimedia applications have diverse resource and timing requirements. A platform for building such programs therefore should supply the developer with mechanisms for managing concurrency, communication, and real-time constraints but should remain flexible with regard to scheduling policies and interaction models. We have developed such a platform consisting of a user-level threads package and operating system extensions. The threads package offers a message-based threading model uniformly integrating synchronous and asynchronous communication, inter-thread synchronization, and signal handling as well as real-time functionality and application-specific scheduling. To support this user-space flexibility an upcall mechanism links the user-level scheduler to the kernel.

  17. EURESCOM Services Platform

    NARCIS (Netherlands)

    Nieuwenhuis, Lambertus Johannes Maria; van Halteren, Aart

    1999-01-01

    This paper presents the results of the EURESCOM Project 715. In February 1999, a large team of researchers from six European public network operators completed a two year period of cooperative experiments on a TINA-based environment, called the EURESCOM Services Platform (ESP). This platform

  18. Managing Clouds in Cloud Platforms

    CERN Document Server

    Ahmat, Kamal A

    2010-01-01

    Managing cloud services is a fundamental challenge in todays virtualized environments. These challenges equally face both providers and consumers of cloud services. The issue becomes even more challenging in virtualized environments that support mobile clouds. Cloud computing platforms such as Amazon EC2 provide customers with flexible, on demand resources at low cost. However, they fail to provide seamless infrastructure management and monitoring capabilities that many customers may need. For instance, Amazon EC2 doesn't fully support cloud services automated discovery and it requires a private set of authentication credentials. Salesforce.com, on the other hand, do not provide monitoring access to their underlying systems. Moreover, these systems fail to provide infrastructure monitoring of heterogenous and legacy systems that don't support agents. In this work, we explore how to build a cloud management system that combines heterogeneous management of virtual resources with comprehensive management of phys...

  19. STUDY OF VARIOUS INTERNET OF THINGS PLATFORMS

    Directory of Open Access Journals (Sweden)

    Bhumi Nakhuva

    2015-12-01

    Full Text Available Internet of Things is a technological revolution which provides the vision of connected world of Things. Devices, people and systems are connected with one another in such a way that they can communicate with each other over Internet. So the form of communication from human-human is now turned into humanhuman, human-things and things- things. Variety of platforms are now a days available that can support entire development to deployment of IoT applications and systems. In this paper, we will first start with the introduction of IoT platforms as well as IoT middleware and then will discuss various IoT platforms, compare various IoT platforms and will end up with the conclusion.

  20. The Common HOL Platform

    OpenAIRE

    Adams, Mark

    2015-01-01

    The Common HOL project aims to facilitate porting source code and proofs between members of the HOL family of theorem provers. At the heart of the project is the Common HOL Platform, which defines a standard HOL theory and API that aims to be compatible with all HOL systems. So far, HOL Light and hol90 have been adapted for conformance, and HOL Zero was originally developed to conform. In this paper we provide motivation for a platform, give an overview of the Common HOL Platform's theory and...

  1. Ladder attachment platform

    Science.gov (United States)

    Swygert,; Richard, W [Springfield, SC

    2012-08-28

    A ladder attachment platform is provided that includes a base for attachment to a ladder that has first and second side rails and a plurality of rungs that extend between in a lateral direction. Also included is a user platform for having a user stand thereon that is carried by the base. The user platform may be positioned with respect to the ladder so that it is not located between a first plane that extends through the first side rail and is perpendicular to the lateral direction and a second plane that extends through the second side rail and is perpendicular to the lateral direction.

  2. SCEC Broadband Platform Strong Ground Motion Simulations

    Science.gov (United States)

    Kumar, S.; Callaghan, S.; Maechling, P. J.; Olsen, K. B.; Archuleta, R. J.; Somerville, P. G.; Graves, R. W.; Jordan, T. H.; Broadband Platform Working Group

    2011-12-01

    The Southern California Earthquake Center (SCEC) Broadband Platform is a collaborative software development project involving SCEC researchers, graduate students, and the SCEC Community Modeling Environment. The goal of the SCEC Broadband Simulation Platform is to generate broadband (0-10 Hz) ground motions for earthquakes using deterministic low-frequency and stochastic high-frequency simulations. SCEC developers have integrated complex scientific modules for rupture generation, low-frequency deterministic seismogram synthesis, high-frequency stochastic seismogram synthesis, and non-linear site effects calculation into a system that supports easy on-demand computation of broadband seismograms. The SCEC Broadband platform has two primary modes of operation, validation mode, and scenario mode. In validation mode, the earthquake modeling software calculates broadband seismograms for one of three earthquakes, Northridge, Loma Prieta, or Landers at sites with observed strong motion data. Then, the platform calculates goodness of fit measurements that quantify how well the model-based broadband seismograms match the observed seismograms for each event. In scenario mode, the user can specify a scenario earthquake and a list of sites and calculate ground motions at each site for the scenario event. In February 2011, SCEC released Broadband Platform 11.2 as an open-source scientific software distribution. Since that time, we have continued development of the platform by adding a new site response module and new goodness of fit measures by Mayhew and Olsen. Along with a source code distribution of the Broadband Platform, we now offer a virtual software image distribution of the platform to support its use on a variety of computing hardware and operating systems.

  3. Platform-based production development

    DEFF Research Database (Denmark)

    Bossen, Jacob; Brunoe, Thomas Ditlev; Nielsen, Kjeld

    2015-01-01

    Platforms as a means for applying modular thinking in product development is relatively well studied, but platforms in the production system has until now not been given much attention. With the emerging concept of platform-based co-development the importance of production platforms is though...... indisputable. This paper presents state-of-the-art literature on platform research related to production platforms and investigates gaps in the literature. The paper concludes on findings by proposing future research directions....

  4. USA Hire Testing Platform

    Data.gov (United States)

    Office of Personnel Management — The USA Hire Testing Platform delivers tests used in hiring for positions in the Federal Government. To safeguard the integrity of the hiring processes and ensure...

  5. MULTIFUNCTIONAL PLATFORMS AND

    African Journals Online (AJOL)

    Solar service centres and multifunctional platforms are innovative concepts for providing energy services in ... same time generate income. obeng ..... communities the driving force behind the ... operator(s) had to contact repairers outside their.

  6. The Common HOL Platform

    Directory of Open Access Journals (Sweden)

    Mark Adams

    2015-07-01

    Full Text Available The Common HOL project aims to facilitate porting source code and proofs between members of the HOL family of theorem provers. At the heart of the project is the Common HOL Platform, which defines a standard HOL theory and API that aims to be compatible with all HOL systems. So far, HOL Light and hol90 have been adapted for conformance, and HOL Zero was originally developed to conform. In this paper we provide motivation for a platform, give an overview of the Common HOL Platform's theory and API components, and show how to adapt legacy systems. We also report on the platform's successful application in the hand-translation of a few thousand lines of source code from HOL Light to HOL Zero.

  7. The Creative Platform

    DEFF Research Database (Denmark)

    Byrge, Christian; Hansen, Søren

    whether you consider thirdgrade teaching, human-resource development, or radical new thinking in product development in a company. The Creative Platform was developed at Aalborg University through a series of research-and-development activities in collaboration with educational institutions and private......This book is about introducing more creativity into general educational courses and cross-disciplinary activities. It is directed toward teachers at all levels in the educational system, but the Creative Platform is a general model, and thus the creative process will fundamentally be the same...... companies. It is a project in which the goal is to make a hands-on approach to a knowledge perspective on enhancing creativity. The underlying ambition of the Creative Platform is to make it easier to promote creativity. At www.uka.aau.dk/The+Creative+Platform, you can find extra materials and instructions...

  8. National Community Solar Platform

    Energy Technology Data Exchange (ETDEWEB)

    Rupert, Bart [Clean Energy Collective, Louisville, CO (United States)

    2016-06-30

    This project was created to provide a National Community Solar Platform (NCSP) portal known as Community Solar Hub, that is available to any entity or individual who wants to develop community solar. This has been done by providing a comprehensive portal to make CEC’s solutions, and other proven community solar solutions, externally available for everyone to access – making the process easy through proven platforms to protect subscribers, developers and utilities. The successful completion of this project provides these tools via a web platform and integration APIs, a wide spectrum of community solar projects included in the platform, multiple groups of customers (utilities, EPCs, and advocates) using the platform to develop community solar, and open access to anyone interested in community solar. CEC’s Incubator project includes web-based informational resources, integrated systems for project information and billing systems, and engagement with customers and users by community solar experts. The combined effort externalizes much of Clean Energy Collective’s industry-leading expertise, allowing third parties to develop community solar without duplicating expensive start-up efforts. The availability of this platform creates community solar projects that are cheaper to build and cheaper to participate in, furthering the goals of DOE’s SunShot Initiative. Final SF 425 Final SF 428 Final DOE F 2050.11 Final Report Narrative

  9. Planning of Creative Commercial Components Virtual Warehouse Platform

    Directory of Open Access Journals (Sweden)

    Wang Yantao

    2013-07-01

    Full Text Available In this study, through the analysis of actual goods warehouse application, creative commercial components virtual warehouse platform over the networks is proposed to support the complex mechanical product commercial work mode. This platform may play an important role during the collaborative commodity design process, especially the geometrical model to the commercial model. First, the framework of commercial design process was described detailed with the supporting of virtual components warehouse platform. Then, those platform features such as networks-based, agent-oriented and enterprises alliance-served were discussed. The platform application modes, on-line stocking and inquiring were also classified. Finally, the planning framework of the commercial components virtual warehouse platform was studied detailed.

  10. Designing a Configurable Services Platform for Mobile Context-Aware Applications

    NARCIS (Netherlands)

    Dockhorn Costa, P.; Ferreira Pires, L.; Sinderen, van M.J.; Yang, L.; Merabti, M.; Ma, J.

    2005-01-01

    Context-aware services platforms aim at supporting the handling of contextual information in order to provide better user-tailored services. This paper proposes a novel services platform architecture to support mobile context-aware applications, giving emphasis to the configurability of the platform

  11. The Platformization of the Web: Making Web Data Platform Ready

    NARCIS (Netherlands)

    A. Helmond

    2015-01-01

    In this article, I inquire into Facebook’s development as a platform by situating it within the transformation of social network sites into social media platforms. I explore this shift with a historical perspective on, what I refer to as, platformization, or the rise of the platform as the dominant

  12. Patterns of Cellular Immunity Associated with Experimental Infection with rDEN2Δ30 (Tonga/74) Support Its Suitability as a Human Dengue Virus Challenge Strain.

    Science.gov (United States)

    Grifoni, Alba; Angelo, Michael; Sidney, John; Paul, Sinu; Peters, Bjoern; de Silva, Aruna D; Phillips, Elizabeth; Mallal, Simon; Diehl, Sean A; Botten, Jason; Boyson, Jonathan; Kirkpatrick, Beth D; Whitehead, Stephen S; Durbin, Anna P; Sette, Alessandro; Weiskopf, Daniela

    2017-04-15

    A deletion variant of the dengue virus (DENV) serotype 2 (DENV2) Tonga/74 strain lacking 30 nucleotides from its 3' untranslated region (rDEN2Δ30) has previously been established for use in a controlled human DENV challenge model. To evaluate if this model is appropriate for the derivation of correlates of protection for DENV vaccines on the basis of cellular immunity, we wanted to compare the cellular immune response to this challenge strain to the response induced by natural infection. To achieve this, we predicted HLA class I- and class II-restricted peptides from rDEN2Δ30 and used them in a gamma interferon enzyme-linked immunosorbent spot assay to interrogate CD8(+) and CD4(+) T cell responses in healthy volunteers infected with rDEN2Δ30. At the level of CD8 responses, vigorous ex vivo responses were detected in approximately 80% of donors. These responses were similar in terms of the magnitude and the numbers of epitopes recognized to the responses previously observed in peripheral blood mononuclear cells from donors from regions where DENV is hyperendemic. The similarity extended to the immunodominance hierarchy of the DENV nonstructural proteins, with NS3, NS5, and NS1 being dominant in both donor cohorts. At the CD4 level, the responses to rDEN2Δ30 vaccination were less vigorous than those to natural DENV infection and were more focused on nonstructural proteins. The epitopes recognized following rDEN2Δ30 infection and natural infection were largely overlapping for both the CD8 (100%) and CD4 (85%) responses. Finally, rDEN2Δ30 induced stronger CD8 responses than other, more attenuated DENV isolates.IMPORTANCE The lack of a known correlate of protection and the failure of a neutralizing antibody to correlate with protection against dengue virus have highlighted the need for a human DENV challenge model to better evaluate the candidate live attenuated dengue vaccines. In this study, we sought to characterize the immune profiles of rDEN2Δ30-infected

  13. Service Delivery Platforms Developing and Deploying Converged Multimedia Services

    CERN Document Server

    Ahson, Syed A

    2011-01-01

    In the telecommunications industry, it is becoming increasingly important for operators to quickly provide a service delivery platform. This book discusses the fundamental requirements of service delivery platforms, evaluating their basic functions and feasibility. Starting with content and media in modern networks, the text presents the entire user experience, including requirements for the user terminal, supporting systems, broadcasting, and networks. Expert contributors explore the evolving role of service delivery platforms, explaining various applications and delivery mechanisms, providin

  14. Platform Performance and Challenges - using Platforms in Lego Company

    DEFF Research Database (Denmark)

    Munk, Lone; Mortensen, Niels Henrik

    2009-01-01

    by the product defining users (product developers) and platform erosion. When the platforms are not used it is due to: unsuitable calculation models, lack of goals, rewards or benefits from management, unattractive tradeoffs and difficulties in understanding the platform. This indicates that platform design...... needs focus on the incentive of using the platform. This problem lacks attention in literature, as well as industry, where assessment criteria do not cover this aspect. Therefore, we recommend including user incentive in platform assessment criteria to these challenges. Concrete solution elements...... ensuring user incentive in platforms is an object for future research...

  15. 基于可靠性的某型平台罗经维修与保障方法%Maintenance and Support Method of a Certain Type of Platform Compass Based on Reliability

    Institute of Scientific and Technical Information of China (English)

    杨国忠; 陈建勋; 何永前

    2012-01-01

    针对某型平台罗经维修要求,结合平台罗经电子机柜特点和当前维修方式与备件储备方式,通过失效样品分析,确定失效机理属性;通过可靠性预计和现场使用数据跟踪分析,建立可靠性水平综合评估模型,从而为平台罗经以可靠性为中心的维修与保障提出探索性解决方案,文章详细讲述了某型平台罗经以可靠性为中心的维修与保障方法的内容、思路、过程,并给出了结论。%According to a certain type of platform compass maintenance requirements, combined with the platform characteristics and the current electronic compass cabinet maintenance way and the spare parts reserve way, through the failure analysis of samples, determine the failure mechanism of the attribute. Through the reliability and the scene is expected to use data tracking analysis, a comprehensive evalu- ation model of reliabilily level, and as a platform to compass reliability centered maintenance and protection of the exploratory solutions pro posed, this paper tells the story of a certain type of platform compass to reliability centered maintenance and protection of the research con- tents, the thought, method, process, and gives the study concluded.

  16. Studies using structural analogs and inbred strain differences to support a role for quinone methide metabolites of butylated hydroxytoluene (BHT) in mouse lung tumor promotion.

    Science.gov (United States)

    Thompson, J A; Carlson, T J; Sun, Y; Dwyer-Nield, L D; Malkinson, A M

    2001-03-07

    Chronic treatment of BALB and GRS mice with BHT (2,6-di-tert-butyl-4-methylphenol) following a single urethane injection increases lung tumor multiplicity, but this does not occur in CXB4 mice. Previous data suggest that promotion requires the conversion of BHT to a tert-butyl-hydroxylated metabolite (BHTOH) in lung and the subsequent oxidation of this species to an electrophilic quinone methide. To obtain additional evidence for the importance of quinone methide formation, structural analogs that form less reactive quinone methides were tested and found to lack promoting activity in BHT-responsive mice. The possibility that promotion-unresponsive strains are unable to form BHTOH was tested by substituting this compound for BHT in the promotion protocol using CXB4 mice. No promotion occurred, and in-vitro work demonstrated that CXB4 mice are, in fact, capable of producing BHTOH and its quinone methide, albeit in smaller quantities. Incubations with BALB lung microsomes and radiolabeled substrates confirmed that more covalent binding to protein occurs with BHTOH than with BHT and, in addition, BHTOH quinone methide is considerably more toxic to mouse lung epithelial cells than BHT quinone methide. These data are consistent with the hypothesis that a two-step oxidation process, i.e. hydroxylation and quinone methide formation, is required for the promotion of mouse lung tumors by BHT.

  17. FDI as an Export-Platform

    DEFF Research Database (Denmark)

    Hajderllari, Luljeta; Karantininis, Konstantinos; Lawson, Lartey Godwin

    towards countries with large exports of agri-food, thereby supporting the hypothesis that FDI is used as an export-platform. FDI is coupled with high exports from Denmark, probably of raw or semi-processed food products for further processing and exports. We also find that FDI is higher in countries...

  18. Application in the construction of the electronic physical network supporting system for the guangxi experimental animals information platform%广西实验动物信息平台电子物理网络支撑体系建设应用

    Institute of Scientific and Technical Information of China (English)

    罗慧; 唐忠

    2016-01-01

    为了协助广西壮族自治区科技厅、自治区实验动物管理委员会对全区实验动物的生产、使用、科研及教育培训提供管理支持,提高全区实验动物资源的利用效率,完成了对广西实验动物信息平台电子物理网络支撑环境的建设。文章主要从广西实验动物信息平台电子物理网络支撑体系建设的目的和意义,以及拟解决的关键问题入手,详细介绍了广西实验动物信息平台电子物理网络支撑体系建设内容和技术构建方案。%In order to assist the Guangxi Science and Technology Department, Guangxi Animal Care Committee of providing management and support for the production, use, research, education and training of the experimental animals all over the region, and improving the utilization efficiency of the region's animal resources, we completed the construction of the electronic physical network supporting environment for the guangxi experimental animals information platform. In this paper, we started with the purpose and significance of the electronic physical network supporting system construction of the guangxi experimental animals information platform and the key issues to be solved, and then introduced the construction content and technology construction plan of the electronic physical network supporting system construction of guangxi experimental animals information platform in detail.

  19. The SNAP Platform: Social Networking for Academic Purposes

    Science.gov (United States)

    Kirkwood, Keith

    2010-01-01

    Purpose: This paper aims to introduce an enterprise-wide Web 2.0 learning support platform--SNAP, developed at Victoria University in Melbourne, Australia. Design/methodology/approach: Pointing to the evolution of the social web, the paper discusses the potential for the development of e-learning platforms that employ constructivist, connectivist,…

  20. Architectural models for client interaction on service-oriented platforms

    NARCIS (Netherlands)

    Bonino da Silva Santos, L.O.; Ferreira Pires, L.; Sinderen, van M.J.; Sinderen, van M.J.

    2007-01-01

    Service-oriented platforms can provide different levels of functionality to the client applications as well as different interaction models. Depending on the platform’s goals and the computing capacity of their expected clients the platform functionality can range from just an interface to support t

  1. Geostationary multipurpose platforms

    Science.gov (United States)

    Bekey, I.; Bowman, R. M.

    1981-01-01

    In addition to the advantages generally associated with orbital platforms, such as improved reliability, economies of scale, simple connectivity of elements, reduced tracking demands and the restraint of orbital object population growth, geostationary platforms yield: (1) continuous access by fixed ground antennas for communications services; (2) continuous monitoring of phenomena over chosen regions of the earth's surface; (3) a preferred location for many solar-terrestrial physics experiments. The geostationary platform also offers a low-risk and economical solution to the impending saturation of the orbital arc/frequency spectrum, maximizing the capacity of individual slots and increasing the utility of the entire arc. It also allows the use of many small, simple and inexpensive earth stations through complexity inversion and high power per beam. Block diagram and operational flowcharts are provided.

  2. Platforms for antibiotic discovery.

    Science.gov (United States)

    Lewis, Kim

    2013-05-01

    The spread of resistant bacteria, leading to untreatable infections, is a major public health threat but the pace of antibiotic discovery to combat these pathogens has slowed down. Most antibiotics were originally isolated by screening soil-derived actinomycetes during the golden era of antibiotic discovery in the 1940s to 1960s. However, diminishing returns from this discovery platform led to its collapse, and efforts to create a new platform based on target-focused screening of large libraries of synthetic compounds failed, in part owing to the lack of penetration of such compounds through the bacterial envelope. This article considers strategies to re-establish viable platforms for antibiotic discovery. These include investigating untapped natural product sources such as uncultured bacteria, establishing rules of compound penetration to enable the development of synthetic antibiotics, developing species-specific antibiotics and identifying prodrugs that have the potential to eradicate dormant persisters, which are often responsible for hard-to-treat infections.

  3. Embedded Linux platform for data acquisition systems

    Energy Technology Data Exchange (ETDEWEB)

    Patel, Jigneshkumar J., E-mail: jjp@ipr.res.in [Institute for Plasma Research, Gandhinagar, Gujarat (India); Reddy, Nagaraj, E-mail: nagaraj.reddy@coreel.com [Sandeepani School of Embedded System Design, Bangalore, Karnataka (India); Kumari, Praveena, E-mail: praveena@ipr.res.in [Institute for Plasma Research, Gandhinagar, Gujarat (India); Rajpal, Rachana, E-mail: rachana@ipr.res.in [Institute for Plasma Research, Gandhinagar, Gujarat (India); Pujara, Harshad, E-mail: pujara@ipr.res.in [Institute for Plasma Research, Gandhinagar, Gujarat (India); Jha, R., E-mail: rjha@ipr.res.in [Institute for Plasma Research, Gandhinagar, Gujarat (India); Kalappurakkal, Praveen, E-mail: praveen.k@coreel.com [Sandeepani School of Embedded System Design, Bangalore, Karnataka (India)

    2014-05-15

    Highlights: • The design and the development of data acquisition system on FPGA based reconfigurable hardware platform. • Embedded Linux configuration and compilation for FPGA based systems. • Hardware logic IP core and its Linux device driver development for the external peripheral to interface it with the FPGA based system. - Abstract: This scalable hardware–software system is designed and developed to explore the emerging open standards for data acquisition requirement of Tokamak experiments. To address the future need for a scalable data acquisition and control system for fusion experiments, we have explored the capability of software platform using Open Source Embedded Linux Operating System on a programmable hardware platform such as FPGA. The idea was to identify the platform which can be customizable, flexible and scalable to support the data acquisition system requirements. To do this, we have selected FPGA based reconfigurable and scalable hardware platform to design the system with Embedded Linux based operating system for flexibility in software development and Gigabit Ethernet interface for high speed data transactions. The proposed hardware–software platform using FPGA and Embedded Linux OS offers a single chip solution with processor, peripherals such ADC interface controller, Gigabit Ethernet controller, memory controller amongst other peripherals. The Embedded Linux platform for data acquisition is implemented and tested on a Virtex-5 FXT FPGA ML507 which has PowerPC 440 (PPC440) [2] hard block on FPGA. For this work, we have used the Linux Kernel version 2.6.34 with BSP support for the ML507 platform. It is downloaded from the Xilinx [1] GIT server. Cross-compiler tool chain is created using the Buildroot scripts. The Linux Kernel and Root File System are configured and compiled using the cross-tools to support the hardware platform. The Analog to Digital Converter (ADC) IO module is designed and interfaced with the ML507 through Xilinx

  4. Windows Azure Platform

    CERN Document Server

    Redkar, Tejaswi

    2011-01-01

    The Windows Azure Platform has rapidly established itself as one of the most sophisticated cloud computing platforms available. With Microsoft working to continually update their product and keep it at the cutting edge, the future looks bright - if you have the skills to harness it. In particular, new features such as remote desktop access, dynamic content caching and secure content delivery using SSL make the latest version of Azure a more powerful solution than ever before. It's widely agreed that cloud computing has produced a paradigm shift in traditional architectural concepts by providin

  5. Windows Azure Platform

    CERN Document Server

    Redkar, Tejaswi

    2010-01-01

    The Azure Services Platform is a brand-new cloud-computing technology from Microsoft. It is composed of four core components-Windows Azure, .NET Services, SQL Services, and Live Services-each with a unique role in the functioning of your cloud service. It is the goal of this book to show you how to use these components, both separately and together, to build flawless cloud services. At its heart Windows Azure Platform is a down-to-earth, code-centric book. This book aims to show you precisely how the components are employed and to demonstrate the techniques and best practices you need to know

  6. Wireless sensor platform

    Energy Technology Data Exchange (ETDEWEB)

    Joshi, Pooran C.; Killough, Stephen M.; Kuruganti, Phani Teja

    2017-08-08

    A wireless sensor platform and methods of manufacture are provided. The platform involves providing a plurality of wireless sensors, where each of the sensors is fabricated on flexible substrates using printing techniques and low temperature curing. Each of the sensors can include planar sensor elements and planar antennas defined using the printing and curing. Further, each of the sensors can include a communications system configured to encode the data from the sensors into a spread spectrum code sequence that is transmitted to a central computer(s) for use in monitoring an area associated with the sensors.

  7. Mobile4D platform

    CSIR Research Space (South Africa)

    Botha, Adèle

    2010-05-01

    Full Text Available . It is a communication platform that has architecture for creating, deploying and managing services and applications by integrating voice, video and data across a range of IP and telecom communication networks. In 2007, Red Hat made a firm commitment... based on the Mobicents muni ations Platform brand. 2.1.5  Telco specific User‐Generated Services   A variety of communication network operators have started initiatives to address User- Generated Services for the Telecom domain. Some...

  8. Multi-platform Multiplayer RPG Game

    OpenAIRE

    Do Manh, Tuan

    2015-01-01

    Title: Multi-platform Multiplayer RPG Game A multi-platform game, which would be able to run on various devices with Windows 8.1 and Windows Phone 8.1 systems, was created in this work. It was supposed to be a universal game client executable on desktop PCs, notebooks, tablets or mobile phones. The game was supposed to be role-playing game (RPG) with focus on turn-based action combat. In this work, a 3D scene renderer was written which supports rendering simple scenes with objects and animate...

  9. Platform for a better built environment.

    Science.gov (United States)

    Baillie, Jonathan

    2014-08-01

    IHEEM's recently established Architecture and Design of the Built Environment Technical Platform (ADBETP) is now firmly up and running, and, as one of its members, Gary Mortimer, general manager, Facilities & Estates, at NHS Grampian, puts it, is 'determined to bring tangible, positive, and sustainable benefits to the NHS built environment to support the effective delivery of changing clinical needs'. Equally, the Platform hopes its activities will 'add value to IHEEM members, technical professionals in health construction and operational management, and other healthcare professionals working in NHS buildings'.

  10. Games and Platform Decisions

    DEFF Research Database (Denmark)

    Hansen, Poul H. Kyvsgård; Mikkola, Juliana Hsuan

    2007-01-01

    is the application of on-line games in order to provide training for decision makers and in order to generate overview over the implications of platform decisions. However, games have to be placed in a context with other methods and we argue that a mixture of games, workshops, and simulations can provide improved...

  11. Creative Platform Learning (CPL)

    DEFF Research Database (Denmark)

    Christensen, Jonna Langeland; Hansen, Søren

    Creative Platform Learning (CPL) er en pædagogisk metode, der skaber foretagsomme og innovative elever, der kan anvende deres kreativitet til at lære nyt. Ifølge den nye skolereform skal Innovation og entreprenørskab tydeliggøres i alle fag. I CPL er det en integreret del af undervisningen...

  12. Games and Platform Decisions

    DEFF Research Database (Denmark)

    Hansen, Poul H. Kyvsgård; Mikkola, Juliana Hsuan

    2007-01-01

    is the application of on-line games in order to provide training for decision makers and in order to generate overview over the implications of platform decisions. However, games have to be placed in a context with other methods and we argue that a mixture of games, workshops, and simulations can provide improved...

  13. PR-PR: cross-platform laboratory automation system.

    Science.gov (United States)

    Linshiz, Gregory; Stawski, Nina; Goyal, Garima; Bi, Changhao; Poust, Sean; Sharma, Monica; Mutalik, Vivek; Keasling, Jay D; Hillson, Nathan J

    2014-08-15

    To enable protocol standardization, sharing, and efficient implementation across laboratory automation platforms, we have further developed the PR-PR open-source high-level biology-friendly robot programming language as a cross-platform laboratory automation system. Beyond liquid-handling robotics, PR-PR now supports microfluidic and microscopy platforms, as well as protocol translation into human languages, such as English. While the same set of basic PR-PR commands and features are available for each supported platform, the underlying optimization and translation modules vary from platform to platform. Here, we describe these further developments to PR-PR, and demonstrate the experimental implementation and validation of PR-PR protocols for combinatorial modified Golden Gate DNA assembly across liquid-handling robotic, microfluidic, and manual platforms. To further test PR-PR cross-platform performance, we then implement and assess PR-PR protocols for Kunkel DNA mutagenesis and hierarchical Gibson DNA assembly for microfluidic and manual platforms.

  14. PR-PR: Cross-Platform Laboratory Automation System

    Energy Technology Data Exchange (ETDEWEB)

    Linshiz, G; Stawski, N; Goyal, G; Bi, CH; Poust, S; Sharma, M; Mutalik, V; Keasling, JD; Hillson, NJ

    2014-08-01

    To enable protocol standardization, sharing, and efficient implementation across laboratory automation platforms, we have further developed the PR-PR open-source high-level biology-friendly robot programming language as a cross-platform laboratory automation system. Beyond liquid-handling robotics, PR-PR now supports microfluidic and microscopy platforms, as well as protocol translation into human languages, such as English. While the same set of basic PR-PR commands and features are available for each supported platform, the underlying optimization and translation modules vary from platform to platform. Here, we describe these further developments to PR-PR, and demonstrate the experimental implementation and validation of PR-PR protocols for combinatorial modified Golden Gate DNA assembly across liquid-handling robotic, microfluidic, and manual platforms. To further test PR-PR cross-platform performance, we then implement and assess PR-PR protocols for Kunkel DNA mutagenesis and hierarchical Gibson DNA assembly for microfluidic and manual platforms.

  15. Communication model of emuStudio emulation platform

    CERN Document Server

    Jakubčo, Peter; Ádám, Norbert

    2010-01-01

    Within the paper a description of communication model of plug-in based emuStudio emulation platform is given. The platform mentioned above allows the emulation of whole computer systems, configurable to the level of its components, represented by the plug-in modules of the platform. Development tasks still are in progress at the home institution of the authors. Currently the platform is exploited for teaching purposes within subjects aimed at machine-oriented languages and computer architectures. Versatility of the platform, given by its plug-in based architecture is a big advantage, when used as a teaching support tool. The paper briefly describes the emuStudio platform at its introductory part and then the mechanisms of inter-module communication are described.

  16. VOLTTRON Lite: Integration Platform for the Transactional Network

    Energy Technology Data Exchange (ETDEWEB)

    Haack, Jereme N.; Katipamula, Srinivas; Akyol, Bora A.; Lutes, Robert G.

    2013-10-31

    In FY13, Pacific Northwest National Laboratory (PNNL) with funding from the Department of Energy’s (DOE’s) Building Technologies Office (BTO) designed, prototyped and tested a transactional network platform. The platform is intended to support energy, operational and financial transactions between any networked entities (equipment, organizations, buildings, grid, etc.). Initially, in FY13, the concept demonstrated transactions between packaged rooftop units (RTUs) and the electric grid using applications or “agents” that reside on the platform, on the equipment, on local building controller or in the Cloud. This document describes the core of the transactional network platform, the Volttron Lite™ software and associated services hosted on the platform. Future enhancements are also discussed. The appendix of the document provides examples of how to use the various services hosted on the platform.

  17. Business and IT Capabilities for Cloud Platform Success

    DEFF Research Database (Denmark)

    Hahn, Christopher; Huntgeburth, Jan; Winkler, Till J.

    2016-01-01

    The growing proliferation of cloud platform ecosystems demands a deeper understanding of the capabilities that help existing and emerging platform providers to be successful by creating and appropriating value. This multiple case study of four cloud platform providers (three large, one SME......) instantiates Rai and Tang’s (2014) framework of dyadic IT and network IT capabilities for a cloud platform context and extends it by exploring previously undertheorized cloud platform business capabilities. We further build on this extended framework by employing a configurational perspective to elucidate...... the complementary role of the three proposed business capabilities (incentives and rules, ecosystem marketing and sales, partner development and support) for relevant value creation and appropriation mechanisms. In addition to providing a capability framework catered to the cloud platform context, our findings...

  18. Seven characteristics of a successful virtual volunteering platform

    CSIR Research Space (South Africa)

    Butgereit, L

    2011-05-01

    Full Text Available characteristics were found to be necessary for platforms which support virtual tutoring to retain their volunteers. It is believed that these seven characteristics apply in general to virtual volunteering and would assist any virtual volunteer organisation...

  19. Communication System for CIMS Application Integration Platform

    Institute of Scientific and Technical Information of China (English)

    1999-01-01

    CIMS has seen the growth of multiple incompatible hardware architectur es, each architecture supporting several incompatible operating systems, and eac h platform operating with various incompatible development tools (e.g., programm ing language compilers, DBMS, etc.) and one or more incompatible graphic user in terfaces. Also, the growth of the Internet, the World-Wide Web, has introduced new dimensio ns of complexity into the development process. All of these must be dealt with a s the application is made workable in a distributed client-server environment. This paper outlines the architecture of a communication system for the CIMS appl ication integration platform. The communication system makes possible the reque st for service across heterogeneous platforms and networks, and provides some co mmon solutions to issues common to CIMS applications.

  20. 微信公众平台支持下的混合式教学在远程开放教育中的实现——以统计学课程学习为例%The Realization of Blended Learning Supported by Wechat Public Platform in Distance and Open Education

    Institute of Scientific and Technical Information of China (English)

    孔杏

    2015-01-01

    The continuous development of information technology and new media and the rapid spread of mobile devices injected new elements for modern distance and open education teaching mode. Wechat as a mobile applications software with communication, social contact and platform capabilities, its powerful features can meet adult learners' demands of "learn at any moment, learn in all places". On the basis of micro-channel analysis platform capabilities will apply open education. Practice has proved that blended learning platform supported by wechat public platform can effectively promote students learning, and offer a new learning approach for adult students.%信息技术、新媒体的不断发展和移动设备的快速普及,为现代远程开放教育教学模式注入了新的元素.微信作为一款具有通讯、社交和平台化功能的移动性应用软件以其强大的功能满足了成人学员"随时可学、随处可学"的需求.在对微信平台功能进行分析的基础上将其应用于开放教育教学过程.实践证明:微信公众平台支持下的混合式教学能有效促进学员的学习,为成人学员提供了一种新的学习途径.

  1. Mobile Platforms and Development Environments

    CERN Document Server

    Helal, Sumi; Li, Wengdong

    2012-01-01

    Mobile platform development has lately become a technological war zone with extremely dynamic and fluid movement, especially in the smart phone and tablet market space. This Synthesis lecture is a guide to the latest developments of the key mobile platforms that are shaping the mobile platform industry. The book covers the three currently dominant native platforms -- iOS, Android and Windows Phone -- along with the device-agnostic HTML5 mobile web platform. The lecture also covers location-based services (LBS) which can be considered as a platform in its own right. The lecture utilizes a sampl

  2. Engineering a microbial platform for de novo biosynthesis of diverse methylxanthines.

    Science.gov (United States)

    McKeague, Maureen; Wang, Yen-Hsiang; Cravens, Aaron; Win, Maung Nyan; Smolke, Christina D

    2016-11-01

    Engineered microbial biosynthesis of plant natural products can support manufacturing of complex bioactive molecules and enable discovery of non-naturally occurring derivatives. Purine alkaloids, including caffeine (coffee), theophylline (antiasthma drug), theobromine (chocolate), and other methylxanthines, play a significant role in pharmacology and food chemistry. Here, we engineered the eukaryotic microbial host Saccharomyces cerevisiae for the de novo biosynthesis of methylxanthines. We constructed a xanthine-to-xanthosine conversion pathway in native yeast central metabolism to increase endogenous purine flux for the production of 7-methylxanthine, a key intermediate in caffeine biosynthesis. Yeast strains were further engineered to produce caffeine through expression of several enzymes from the coffee plant. By expressing combinations of different N-methyltransferases, we were able to demonstrate re-direction of flux to an alternate pathway and develop strains that support the production of diverse methylxanthines. We achieved production of 270μg/L, 61μg/L, and 3700μg/L of caffeine, theophylline, and 3-methylxanthine, respectively, in 0.3-L bench-scale batch fermentations. The constructed strains provide an early platform for de novo production of methylxanthines and with further development will advance the discovery and synthesis of xanthine derivatives.

  3. Web platform for functional design

    Science.gov (United States)

    Dijmarescu, M. R.; Dijmarescu, M. C.

    2015-11-01

    Today's global competitive trends, especially those related to industries, determine a much higher degree of pressure and demands for substantial innovation driven improvements, flexible and time sensitive solutions. Improving and optimizing the design activity by shortening its timeline and maintaining a high quality level for its output have become the main success factors. The evolution of design activity is strongly related to the evolution of education and research made in the design field. Thus, the development of web tools which can contain knowledge about mechanical products functionality and structure may be an important achievement for the education and industry. This paper presents a web platform which contains functional-constructive knowledge in the area of mechanical design field and was developed to support design activity. The proposed web tool can provide any user, even one without background in design theory, information about the functionality of products and the way it is related to the product structure.

  4. Platform for controlled supramolecular nanoassembly.

    Science.gov (United States)

    Czolkos, Ilja; Hannestad, Jonas K; Jesorka, Aldo; Kumar, Ravindra; Brown, Tom; Albinsson, Bo; Orwar, Owe

    2009-06-01

    We here present a two-dimensional (2D) micro/nano-fluidic technique where reactant-doped liquid-crystal films spread and mix on micro- and nanopatterned substrates. Surface-supported phospholipid monolayers are individually doped with complementary DNA molecules which hybridize when these lipid films mix. Using lipid films to convey reactants reduces the dimensionality of traditional 3D chemistry to 2D, and possibly to 1D by confining the lipid film to nanometer-sized lanes. The hybridization event was observed by FRET using single-molecule-sensitive confocal fluorescence detection. We could successfully detect hybridization in lipid streams on 250 nm wide lanes. Our results show that the number and density of reactants as well as sequence of reactant addition can be controlled within confined liquid crystal films, providing a platform for nanochemistry with potential for kinetic control.

  5. ROHDIP: Resource Oriented Heterogeneous Data Integration Platform

    Directory of Open Access Journals (Sweden)

    Wael Shehab

    2016-09-01

    Full Text Available During the last few years, the revolution of social networks such as Facebook, Twitter, and Instagram led to a daily increasing of data that are heterogeneous in their sources, data models, and platforms. Heterogeneous data sources have many forms such as the www, deep web, relational databases systems, No-SQL database systems, hierarchal data systems, semi-structured files, in which data are usually allocated on different machines (distributed and have different data models (heterogeneous. Large-scale data integration efforts demonstrate that their most valuable contribution is implementing a data integration platform that provides a uniform access to the heterogeneous data sources, as well as the different versions of data reported by the same data source over time. Furthermore, the platform must be able to integrate data from a broad range of data authoring devices and database management systems. It also should be accessible by almost types of data querying devices to ensure globally querying the integration platform from any place on earth anytime and receiving the query result in any data format. In this paper, we create a resource oriented heterogeneous data integration platform (ROHDIP that facilitates the data integration process and implements the objectives discussed above. We use the resource oriented architecture ROA to support the uniform access by most types of data querying devices from anywhere and to improve the query response time.

  6. 29 CFR 1910.66 - Powered platforms for building maintenance.

    Science.gov (United States)

    2010-07-01

    ... supported carriages shall be obtained by gravity, by an attachment to a structural support, or by a combination of gravity and a structural support. The use of flowing counterweights to achieve stability is... platform, and this calculated value shall include the effect of one and one-half times the stall capacity...

  7. Low-cost microcontroller platform for studying lymphatic biomechanics in vitro.

    Science.gov (United States)

    Kornuta, Jeffrey A; Nipper, Matthew E; Dixon, J Brandon

    2013-01-04

    The pumping innate to collecting lymphatic vessels routinely exposes the endothelium to oscillatory wall shear stress and other dynamic forces. However, studying the mechanical sensitivity of the lymphatic endothelium remains a difficult task due to limitations of commercial or custom systems to apply a variety of time-varying stresses in vitro. Current biomechanical in vitro testing devices are very expensive, limited in capability, or highly complex; rendering them largely inaccessible to the endothelial cell biology community. To address these shortcomings, the authors propose a reliable, low-cost platform for augmenting the capabilities of commercially available pumps to produce a wide variety of flow rate waveforms. In particular, the Arduino Uno, a microcontroller development board, is used to provide open-loop control of a digital peristaltic pump using precisely timed serial commands. In addition, the flexibility of this platform is further demonstrated through its support of a custom-built cell-straining device capable of producing oscillatory strains with varying amplitudes and frequencies. Hence, this microcontroller development board is shown to be an inexpensive, precise, and easy-to-use tool for supplementing in vitro assays to quantify the effects of biomechanical forces on lymphatic endothelial cells. Copyright © 2012 Elsevier Ltd. All rights reserved.

  8. Magnetic support system

    NARCIS (Netherlands)

    Nijsse, G.J.P.; Spronck, J.W.

    1999-01-01

    There is described a support system enabling supporting an object such as a platform (1) free from vibration, in that bearing elements (50) have a stiffness (k) which at a working point (z0) equals zero. A bearing element (50) comprises two magnetic couplings (51, 52) provided by permanent magnets

  9. Magnetic support system

    NARCIS (Netherlands)

    Nijsse, G.J.P.; Spronck, J.W.

    1999-01-01

    There is described a support system enabling supporting an object such as a platform (1) free from vibration, in that bearing elements (50) have a stiffness (k) which at a working point (z0) equals zero. A bearing element (50) comprises two magnetic couplings (51, 52) provided by permanent magnets (

  10. Evaluation of a hollow fiber supported liquid membrane device as a chemical surrogate for the measurements of zinc (II) bioavailability using two microalgae strains as biological references.

    Science.gov (United States)

    Rodríguez-Morales, Erik A; Rodríguez de San Miguel, Eduardo; de Gyves, Josefina

    2017-03-01

    The environmental bioavailability of zinc (II), i.e., the uptake of the element by an organism, was determined using two microalgae species, Scenedesmus acutus and Pseudokirchneriella subcapitata, and estimated using hollow fiber supported liquid membrane (HF-SLM) device as the chemical surrogate. Several experimental conditions were studied including the presence of organic matter, inorganic anions and concomitant cations and pH. The results show strong positive correlation coefficients between the responses given by the HF-SLM and the microalgae species (r = 0.900 for S. acutus and r = 0.876 for P. subcapitata) in multivariate environments (changes in pH, calcium, humic and citrate concentrations). The maximum amount of zinc (II) retained by the HF-SLM (4.7 × 10(-8) mol/cm(2)) was higher than those for P. subcapitata and S. acutus (9.4 × 10(-11) mol/cm(2) and 6.2 × 10(-11) mol/cm(2), respectively). The variation in pH (pH 5.5-9) was the variable with the greatest effect on zinc internalization in all systems, increasing approximately 2.5 times for P. subcapitata and 5.5 times for S. acutus respect to pH = 5.5, while the presence of humic acids did not affect the response. The species' concentration analysis of the experimental design at pH = 5.5 indicated that the amount of internalized zinc (II) by the HF-SLM and both microalgae species is strongly dependent on the free zinc concentration (r = 0.910 for the HF-SLM, r = 0.922 for S. acutus and r = 0.954 for P. subcapitata); however, at pH = 9.0, the amount of internalized zinc (II) is strongly dependent on the sum of free zinc and labile species (r = 0.912 for the HF-SLM, r = 0.947 for S. acutus and r = 0.900 for P. subcapitata). The presence of inorganic ligands (chloride, sulfate, phosphate, carbonate, and nitrate) and metal ions (cobalt (II), copper (II), nickel (II), chromium (VI), lead (II) and cadmium (II)) produced different behaviors both in the chemical surrogate and the

  11. Load Identification of Offshore Platform for Fatigue Life Estimation

    DEFF Research Database (Denmark)

    Perisic, Nevena; Kirkegaard, Poul Henning; Tygesen, Ulf T.

    2014-01-01

    -assessment of offshore platforms. Structural monitoring systems (SMSs) on offshore structures typically consist of a set of sensors such as strain gauges, accelerometers, wave radars and GPSs, however direct measuring of the actual loading is usually not feasible. One approach is to measure the loads indirectly...

  12. Online stock trading platform

    Directory of Open Access Journals (Sweden)

    Ion LUNGU

    2006-01-01

    Full Text Available The Internet is the perfect tool that can assure the market’s transparency for any user who wants to trade on the stock market. The investor can have access to the market news, financial calendar or the press releases of the issuers. A good online trading platform also provides real-time intraday quotes, trading history and technical analysis giving the investor a clearer view of the supply and demand in the market. All this information provides the investor a good image of the market and encourages him to trade. This paper wishes to draft the pieces of an online trading platform and to analyze the impact of developing and implementing one in a brokerage firm.

  13. Available: motorised platform

    CERN Document Server

    The COMPASS collaboration

    2014-01-01

    The COMPASS collaboration would like to offer to a new owner the following useful and fully operational piece of equipment, which is due to be replaced with better adapted equipment.   Please contact Erwin Bielert (erwin.bielert@cern.ch or 160539) for further information.  Motorized platform (FOR FREE):   Fabricated by ACL (Alfredo Cardoso & Cia Ltd) in Portugal. The model number is MeXs 5-­‐30.  Specifications: 5 m wide, 1 m deep, adjustable height (1.5 m if folded). Maximum working floor height: 4 m. conforms to CERN regulations, number LV158. Type LD500, capacity 500 kg and weight 2000 kg.  If no interested party is found before December 2014, the platform will be thrown away.

  14. Video analysis platform

    OpenAIRE

    FLORES, Pablo; Arias, Pablo; Lecumberry, Federico; Pardo, Álvaro

    2006-01-01

    In this article we present the Video Analysis Platform (VAP) which is an open source software framework for video analysis, processing and description. The main goals of VAP are: to provide a multiplatform system which allows the easy implementation of video algorithms, provide structures and algorithms for the segmentation of video data in its different levels of abstraction: shots, frames, objects, regions, etc, permit the generation and comparison of MPEG7-like descriptors, and develop tes...

  15. Cloud Robotics Platforms

    Directory of Open Access Journals (Sweden)

    Busra Koken

    2015-01-01

    Full Text Available Cloud robotics is a rapidly evolving field that allows robots to offload computation-intensive and storage-intensive jobs into the cloud. Robots are limited in terms of computational capacity, memory and storage. Cloud provides unlimited computation power, memory, storage and especially collaboration opportunity. Cloud-enabled robots are divided into two categories as standalone and networked robots. This article surveys cloud robotic platforms, standalone and networked robotic works such as grasping, simultaneous localization and mapping (SLAM and monitoring.

  16. HPC - Platforms Penta Chart

    Energy Technology Data Exchange (ETDEWEB)

    Trujillo, Angelina Michelle [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-10-08

    Strategy, Planning, Acquiring- very large scale computing platforms come and go and planning for immensely scalable machines often precedes actual procurement by 3 years. Procurement can be another year or more. Integration- After Acquisition, machines must be integrated into the computing environments at LANL. Connection to scalable storage via large scale storage networking, assuring correct and secure operations. Management and Utilization – Ongoing operations, maintenance, and trouble shooting of the hardware and systems software at massive scale is required.

  17. IP Rights and Technological Platforms

    OpenAIRE

    Robert P. Merges

    2008-01-01

    This paper is about intellectual property rights (IPRs) and platform technologies. After a brief introduction explaining some basics of networks, standards and platforms, I turn to three policy issues. The first is the role of IP in what might be termed platform policies, the decisions by courts and regulators concerning whether and how to promote multi-party access to important digital platforms such as media player hardware, cell phones, PCs, and the like. I argue that for the most part the...

  18. Frequency-domain and Time-domain Motion Response Analysis of Mat-supported Jack-up Platform Positioning Process%沉垫自升式平台就位过程运动响应频域与时域分析

    Institute of Scientific and Technical Information of China (English)

    张兆德; 王玉红; 陈伟

    2016-01-01

    Considering the fact that the 4-leg anchor chains are floating during the mat-supported jack-up platform positioning process, the influence of wind, wave and current may induce 6 DOF motion responses of the platform. If the responses are too large, the normal platform installation will be disturbed, even its safety would be hazarded. Based on 3D potential theory and Morison equation, the platform motion responses during positioning process are analyzed respectively in the frequency domain and time domain using SESAM, a powerful hydrodynamic calculation analysis software. The anchor line strength is also checked based on the line tension time history curve. The result shows that the wave incoming direction and period have large influence on the platform motion, and the pitch and roll motions are more sensitive to the wave incoming direction; the platform motion response in time-domain considering the interaction between platform and anchor lines is close to the maximum value of short term prediction in the frequency domain; the platform has excellent motion performance under this condition, the frequency-domain and time-domain results can both meet the operation requirements, and the tension in the anchor lines can meet the strength requirement.%针对沉垫自升式平台在下放过程中四角系有锚链且处于漂浮状态,在风、浪、流的作用下会产生六个自由度的运动响应,若响应过大,会影响平台的正常安装甚至危及平台安全。采用三维势流理论和Morison公式,运用大型水动力计算分析软件 SESAM,分别在频域和时域范围内对平台就位过程的运动响应进行了分析,并通过锚链的张力时历曲线对锚链的强度进行校核。结果表明,波浪的入射角和周期对平台运动有很大的影响,且纵摇和横摇对波浪的入射方向更加敏感,时域范围内考虑平台和锚链耦合作用影响下平台的运动响应和频域范围内短期预报的最大

  19. "Platform switching": Serendipity

    Directory of Open Access Journals (Sweden)

    N Kalavathy

    2014-01-01

    Full Text Available Implant dentistry is the latest developing field in terms of clinical techniques, research, material science and oral rehabilitation. Extensive work is being done to improve the designing of implants in order to achieve better esthetics and function. The main drawback with respect to implant restoration is achieving good osseointegration along with satisfactory stress distribution, which in turn will improve the prognosis of implant prosthesis by reducing the crestal bone loss. Many concepts have been developed with reference to surface coating of implants, surgical techniques for implant placement, immediate and delayed loading, platform switching concept, etc. This article has made an attempt to review the concept of platform switching was in fact revealed accidentally due to the nonavailability of the abutment appropriate to the size of the implant placed. A few aspect of platform switching, an upcoming idea to reduce crestal bone loss have been covered. The various methods used for locating and preparing the data were done through textbooks, Google search and related articles.

  20. "Platform switching": serendipity.

    Science.gov (United States)

    Kalavathy, N; Sridevi, J; Gehlot, Roshni; Kumar, Santosh

    2014-01-01

    Implant dentistry is the latest developing field in terms of clinical techniques, research, material science and oral rehabilitation. Extensive work is being done to improve the designing of implants in order to achieve better esthetics and function. The main drawback with respect to implant restoration is achieving good osseointegration along with satisfactory stress distribution, which in turn will improve the prognosis of implant prosthesis by reducing the crestal bone loss. Many concepts have been developed with reference to surface coating of implants, surgical techniques for implant placement, immediate and delayed loading, platform switching concept, etc. This article has made an attempt to review the concept of platform switching was in fact revealed accidentally due to the nonavailability of the abutment appropriate to the size of the implant placed. A few aspect of platform switching, an upcoming idea to reduce crestal bone loss have been covered. The various methods used for locating and preparing the data were done through textbooks, Google search and related articles.

  1. Platform computing powers enterprise grid

    CERN Multimedia

    2002-01-01

    Platform Computing, today announced that the Stanford Linear Accelerator Center is using Platform LSF 5, to carry out groundbreaking research into the origins of the universe. Platform LSF 5 will deliver the mammoth computing power that SLAC's Linear Accelerator needs to process the data associated with intense high-energy physics research (1 page).

  2. A survey on platforms for big data analytics.

    Science.gov (United States)

    Singh, Dilpreet; Reddy, Chandan K

    The primary purpose of this paper is to provide an in-depth analysis of different platforms available for performing big data analytics. This paper surveys different hardware platforms available for big data analytics and assesses the advantages and drawbacks of each of these platforms based on various metrics such as scalability, data I/O rate, fault tolerance, real-time processing, data size supported and iterative task support. In addition to the hardware, a detailed description of the software frameworks used within each of these platforms is also discussed along with their strengths and drawbacks. Some of the critical characteristics described here can potentially aid the readers in making an informed decision about the right choice of platforms depending on their computational needs. Using a star ratings table, a rigorous qualitative comparison between different platforms is also discussed for each of the six characteristics that are critical for the algorithms of big data analytics. In order to provide more insights into the effectiveness of each of the platform in the context of big data analytics, specific implementation level details of the widely used k-means clustering algorithm on various platforms are also described in the form pseudocode.

  3. Combating Ebola with Repurposed Therapeutics Using the CANDO Platform

    Directory of Open Access Journals (Sweden)

    Gaurav Chopra

    2016-11-01

    Full Text Available Ebola virus disease (EVD is extremely virulent with an estimated mortality rate of up to 90%. However, the state-of-the-art treatment for EVD is limited to quarantine and supportive care. The 2014 Ebola epidemic in West Africa, the largest in history, is believed to have caused more than 11,000 fatalities. The countries worst affected are also among the poorest in the world. Given the complexities, time, and resources required for a novel drug development, finding efficient drug discovery pathways is going to be crucial in the fight against future outbreaks. We have developed a Computational Analysis of Novel Drug Opportunities (CANDO platform based on the hypothesis that drugs function by interacting with multiple protein targets to create a molecular interaction signature that can be exploited for rapid therapeutic repurposing and discovery. We used the CANDO platform to identify and rank FDA-approved drug candidates that bind and inhibit all proteins encoded by the genomes of five different Ebola virus strains. Top ranking drug candidates for EVD treatment generated by CANDO were compared to in vitro screening studies against Ebola virus-like particles (VLPs by Kouznetsova et al. and genetically engineered Ebola virus and cell viability studies by Johansen et al. to identify drug overlaps between the in virtuale and in vitro studies as putative treatments for future EVD outbreaks. Our results indicate that integrating computational docking predictions on a proteomic scale with results from in vitro screening studies may be used to select and prioritize compounds for further in vivo and clinical testing. This approach will significantly reduce the lead time, risk, cost, and resources required to determine efficacious therapies against future EVD outbreaks.

  4. Development of an experimentally supported evaluation method for optimization and characterization of strain transfer of surface-applied Fibre Bragg Gratings (FBG); Entwicklung eines experimentell gestuetzten Bewertungsverfahrens zur Optimierung und Charakterisierung der Dehnungsuebertragung oberflaechenapplizierter Faser-Bragg-Gitter-Sensoren

    Energy Technology Data Exchange (ETDEWEB)

    Schlueter, Vivien Gisela

    2010-05-01

    Fibre Bragg Gratings (FBG) as strain sensors are implemented in those areas, where conventional electrical strain gauges reach their limits (for example in areas of high voltage, strong electro-magnetic fields, medical technology, safety relevant and radiation-exposed areas). Subject of this work is the surface application and the qualification of these sensors as strain sensors on different materials. A certified and proven method of application for surface mounted sensors is not known yet. The determination of the strain transfer and the definition of a strain transfer factor out of the relation between the Bragg wavelength change and the strain of the specimen have not yet been validated experimentally with an independent validation method. The development of an experimental methodology using a physically independent optical reference method for the determination of the strain transfer between the specimen and the FBG strain sensor is the main focus of this work. The influencing parameters on the strain distribution have been quantified experimentally and the change in Bragg wavelength has been investigated in relation to the strain measured by strain gauges. The material properties of the adhesives have been partly investigated. On the basis of these experiments a testing facility for surface applied FBG strain sensors has been developed. The functionality of the experimental methodology for the determination of the strain factor has been shown. The characterisation of the testing facility and the validity of FBG strain sensors through the experimental methodology inhere developed have been started. For the case of the strain determination in wind turbine rotor blades specially adapted FBG patches have been developed and qualified. An integration technique for FBG strain sensors into the rotor blade has been developed as well. As a first step of standardizing this measurement technique a national standard has been developed under the contribution of the author

  5. Damage Localization of Offshore Platforms Under Ambient Excitation

    Institute of Scientific and Technical Information of China (English)

    杨和振; 李华军; 王树青

    2003-01-01

    In this paper Nondestructive Damage Detection (NDD) for offshore platforms is investigated under operational conditions. As is known, there is no easy way to measure ambient excitation, so damage detection methods based on ambient excitation have become very vital for the Structural Health Monitoring (SHM) of offshore platforms. The modal parameters (natural frequencies, damping ratios and mode shapes) are identified from structural response data with the Natural Excitation Technique (NExT) in conjunction with the Eigensystem Realization Algorithm (ERA). A new method of damage detection is presented, which utilizes the invariance property of element modal strain energy. This method is to assign element modal strain energy to two parts, and defines two damage detection indicators. One is compression modal strain energy change ratio (CMSECR); the other is flexural modal strain energy change ratio (FMSECR). The present modal strain energy is obtained by incomplete modal shape and structural stiffness matrix. Structural health monitoring is thus accomplished via monitoring the elemental CMSECR and FMSECR. Several damage cases are simulated by an offshore platform numerical model, and presented to illustrate the utility of the proposed method. According to the damage localization results, the proposed method is shown to be effective and precise for complex structural damage detection.

  6. Design of Direct Trading Platform for Electricity Users and Power Generation Enterprises Supporting Whole Business Procedure%支持全业务运作的电力用户与发电企业直接交易平台设计

    Institute of Scientific and Technical Information of China (English)

    张显; 郑亚先; 耿建; 黄龙达; 龙苏岩; 刘永辉

    2016-01-01

    As the first technical supporting platform for the whole business procedure of direct trading between electricity users and power generation enterprises in China,the design objective of the platform is introduced.The architecture design is described from the following four aspects:business architecture,application architecture,data architecture and technical architecture.The transaction management of multiple varieties,same-schedule rolling compilation of generating planning, unified settlement of multiple components of electricity quantity,data platform based on dimension decomposition and other key techniques are also analyzed.The platform has been practically applied in the building of state grid unified national electricity market,supporting the direct trading for large-power-end users in more than twenty provinces,including Shanxi, Anhui,Gansu and other pilot provinces.%作为国内首套支撑电力用户与发电企业直接交易全业务流程的技术支撑平台,文中介绍了该平台的设计目标,从业务架构、功能架构、数据架构、技术架构4个方面阐述了平台的设计架构,分析了多品种交易管理、发电计划等进度滚动编制、多电量成分统一结算、基于维度分解的数据交互等平台关键技术。该平台已在国家电网全国统一电力市场建设中得到实际应用,支撑包括山西、安徽、甘肃等试点省在内的20余个省大用户直接交易的开展。

  7. LXI instrument development platform based on an open embedded operating system

    Institute of Scientific and Technical Information of China (English)

    Yu Wilson

    2007-01-01

    This paper introduces the architecture and components of LXI instrument development platform based on an open embedded operating system, which is a modular and configurable platform. The platform is a total solution to develop LXI instrument modules and systems. On the other hand, it also supports other types of instrument development. This is a generic and efficient platform. At the end, this paper addresses the technical tends,challenges, and recommends solutions.

  8. Internet Based General Computer Simulation Platform for Distributed Multi-Robotic System

    Institute of Scientific and Technical Information of China (English)

    迟艳玲; 张斌; 王硕; 谭民

    2002-01-01

    A general computer simulation platform is designed for the purpose of catrrying out experiments on the Distributed Multi-Robotic System. The simulation platform is based on Internet and possesses generality, validity, real-time display and function of supporting algorithm developing. In addition, the platform is equipped wit recording and replay module, and simulation experiment can be reviewed at anytime.By now; a few algorithms have been developed on the Simulation Platform designed.

  9. Full Genome Sequence of Giant Panda Rotavirus Strain CH-1

    Science.gov (United States)

    Guo, Ling; Yang, Shaolin; Wang, Chengdong; Chen, Shijie; Yang, Xiaonong; Hou, Rong; Quan, Zifang; Hao, Zhongxiang

    2013-01-01

    We report here the complete genomic sequence of the giant panda rotavirus strain CH-1. This work is the first to document the complete genomic sequence (segments 1 to 11) of the CH-1 strain, which offers an effective platform for providing authentic research experiences to novice scientists. PMID:23469354

  10. Cytostretch, an Organ-on-Chip Platform

    Directory of Open Access Journals (Sweden)

    Nikolas Gaio

    2016-07-01

    Full Text Available Organ-on-Chips (OOCs are micro-fabricated devices which are used to culture cells in order to mimic functional units of human organs. The devices are designed to simulate the physiological environment of tissues in vivo. Cells in some types of OOCs can be stimulated in situ by electrical and/or mechanical actuators. These actuations can mimic physiological conditions in real tissue and may include fluid or air flow, or cyclic stretch and strain as they occur in the lung and heart. These conditions similarly affect cultured cells and may influence their ability to respond appropriately to physiological or pathological stimuli. To date, most focus has been on devices specifically designed to culture just one functional unit of a specific organ: lung alveoli, kidney nephrons or blood vessels, for example. In contrast, the modular Cytostretch membrane platform described here allows OOCs to be customized to different OOC applications. The platform utilizes silicon-based micro-fabrication techniques that allow low-cost, high-volume manufacturing. We describe the platform concept and its modules developed to date. Membrane variants include membranes with (i through-membrane pores that allow biological signaling molecules to pass between two different tissue compartments; (ii a stretchable micro-electrode array for electrical monitoring and stimulation; (iii micro-patterning to promote cell alignment; and (iv strain gauges to measure changes in substrate stress. This paper presents the fabrication and the proof of functionality for each module of the Cytostretch membrane. The assessment of each additional module demonstrate that a wide range of OOCs can be achieved.

  11. Cots Correlator Platform

    Science.gov (United States)

    Schaaf, Kjeld; Overeem, Ruud

    2004-06-01

    Moore’s law is best exploited by using consumer market hardware. In particular, the gaming industry pushes the limit of processor performance thus reducing the cost per raw flop even faster than Moore’s law predicts. Next to the cost benefits of Common-Of-The-Shelf (COTS) processing resources, there is a rapidly growing experience pool in cluster based processing. The typical Beowulf cluster of PC’s supercomputers are well known. Multiple examples exists of specialised cluster computers based on more advanced server nodes or even gaming stations. All these cluster machines build upon the same knowledge about cluster software management, scheduling, middleware libraries and mathematical libraries. In this study, we have integrated COTS processing resources and cluster nodes into a very high performance processing platform suitable for streaming data applications, in particular to implement a correlator. The required processing power for the correlator in modern radio telescopes is in the range of the larger supercomputers, which motivates the usage of supercomputer technology. Raw processing power is provided by graphical processors and is combined with an Infiniband host bus adapter with integrated data stream handling logic. With this processing platform a scalable correlator can be built with continuously growing processing power at consumer market prices.

  12. Hip flexor strain - aftercare

    Science.gov (United States)

    ... flexor - aftercare; Hip flexor injury - aftercare; Hip flexor tear - aftercare; Iliopsoas strain - aftercare; Strained iliopsoas muscle - aftercare; Torn iliopsoas muscle - aftercare; Psoas strain - aftercare

  13. Emergence of a multidrug-resistant (ASSuTTm) strain of Salmonella enterica serovar Typhimurium DT120 in England in 2011 and the use of multiple-locus variable-number tandem-repeat analysis in supporting outbreak investigations.

    Science.gov (United States)

    Paranthaman, Karthikeyan; Haroon, Sophie; Latif, Samia; Vinnyey, Natalie; de Souza, Valerie; Welfare, William; Tahir, Mamoona; Cooke, Edward; Stone, Kirsten; Lane, Chris; Peters, Tansy; Puleston, Richard

    2013-10-01

    In summer 2011, two outbreaks of a unique, multidrug-resistant strain of Salmonella enterica serovar Typhimurium phage type 120 (DT120) occurred mainly in the Midlands, England. The first outbreak occurred among guests attending a wedding in July 2011 ('Wedding outbreak'), followed by a more geographically dispersed outbreak in August and September 2011 ('Midlands outbreak'). Fifty-one cases were confirmed. Detailed epidemiological and environmental health investigations suggested that pork was the most likely source of both outbreaks. All human samples and one pork sample showed the specific multiple-locus variable-number tandem-repeat analysis (MLVA) profile 3-11-12-NA-0211, with at most two loci variations. Trace-back investigations suggested a link to a butcher's shop and a pig farm in the East Midlands. The investigations highlight the utility of molecular analysis (MLVA) in supporting epidemiological investigations of outbreaks caused by S. Typhimurium DT120. Safe handling and cooking of pork by food business operators and consumers are key interventions to prevent future outbreaks.

  14. Design and development of the individualized teaching system support platform of teaching resource database for Computer Application Technology%个性化计算机应用技术专业教学资源库教学系统支持平台的设计与开发

    Institute of Scientific and Technical Information of China (English)

    黄力明

    2015-01-01

    This paper introduces the design and realization of the individualized teaching system support platform of teaching resource database for Computer Application Technology.The function modules of the system includes teaching plan,exercise test,question answering,test,and all teaching links.Using the internet platform and the browser software,students can refer to the learning strategies system provided by free and flexible ways to complete all learning tasks of the course and teachers can easily complete all the teaching activities.%介绍计算机应用技术专业教学资源库教学系统支持平台的设计与实现,该系统包括课程教案、习题测验、答疑、考试等全部教学环节在内的功能模块。通过Internet平台并利用浏览器软件,学生可参考系统提供的学习策略采用自由灵活的方式完成课程的全部学习任务,教师可轻松地完成课程的全部教学活动。

  15. System/Design Trade Study Report for the Navigation of the Airborne, Ground Vehicular and Man-Portable Platforms in Support of the Buried Ordnance Detection, Identification, and Remediation Technology.

    Science.gov (United States)

    1995-03-01

    AND ADDRESS(ES) Naval Explosive Ordnance Disposal Technology Division Project Manager: Gerard Snyder 301/743-6855 2008 Stump Neck Road Indian Head ...NUMBER 10. SPONSORING / MONITORING AGENCY REPORT NUMBER SFIM-AEC-ET-CR-95043 Supporting Contractor: PRC, Inc. 801 North Strauss Avenue Indian Head ...available on the market today for detection, mapping and remediation of hazardous materials have not been developed to the level that could be

  16. Venus Atmospheric Maneuverable Platform (VAMP)

    Science.gov (United States)

    Polidan, R.; Lee, G.; Sokol, D.; Griffin, K.; Bolisay, L.; Barnes, N.

    2014-04-01

    Over the past years we have explored a possible new approach to Venus upper atmosphere exploration by applying recent Northrop Grumman (non-NASA) development programs to the challenges associated with Venus upper atmosphere science missions. Our concept is a low ballistic coefficient (aircraft that deploys prior to entering the Venus atmosphere, enters the Venus atmosphere without an aeroshell, and provides a long-lived (months to years), maneuverable vehicle capable of carrying science payloads to explore the Venus upper atmosphere. VAMP targets the global Venus atmosphere between 55 and 70 km altitude and would be a platform to address VEXAG goals I.A, I.B, and I.C. We will discuss the overall mission architecture and concept of operations from launch through Venus arrival, orbit, entry, and atmospheric science operations. We will present a strawman concept of VAMP, including ballistic coefficient, planform area, percent buoyancy, inflation gas, wing span, vehicle mass, power supply, propulsion, materials considerations, structural elements, subsystems, and packaging. The interaction between the VAMP vehicle and the supporting orbiter will also be discussed. In this context, we will specifically focus upon four key factors impacting the design and performance of VAMP: 1. Science payload accommodation, constraints, and opportunities 2. Characteristics of flight operations and performance in the Venus atmosphere: altitude range, latitude and longitude access, day/night performance, aircraft performance, performance sensitivity to payload weight 3. Feasibility of and options for the deployment of the vehicle in space 4. Entry into the Venus atmosphere, including descent profile, heat rate, total heat load, stagnation temperature, control, and entry into level flight We will discuss interdependencies of the above factors and the manner in which the VAMP strawman's characteristics affect the CONOPs and the science objectives. We will show how the these factors provide

  17. Towards a web-based archaeological excavation platform for smartphones: review and potentials.

    Science.gov (United States)

    Styliaras, Georgios

    2015-01-01

    The paper conducts a review questioning the usability of a web-based platform supporting archaeological excavations and related fields, which will execute on smartphones. Based on the thorough review and comparison of related work, the basic features of such a platform are outlined. The platform should support documenting content on an underlying XML database through a content management system, producing and exchanging notes, map interaction, use of a shared whiteboard, collaboration among archaeologists etc. The architecture of the platform is presented along with two case studies supporting usual practices on an archaeological field, some primary evaluation results and future work.

  18. Protective efficacy of multiple vaccine platforms against Zika virus challenge in rhesus monkeys.

    Science.gov (United States)

    Abbink, Peter; Larocca, Rafael A; De La Barrera, Rafael A; Bricault, Christine A; Moseley, Edward T; Boyd, Michael; Kirilova, Marinela; Li, Zhenfeng; Ng'ang'a, David; Nanayakkara, Ovini; Nityanandam, Ramya; Mercado, Noe B; Borducchi, Erica N; Agarwal, Arshi; Brinkman, Amanda L; Cabral, Crystal; Chandrashekar, Abishek; Giglio, Patricia B; Jetton, David; Jimenez, Jessica; Lee, Benjamin C; Mojta, Shanell; Molloy, Katherine; Shetty, Mayuri; Neubauer, George H; Stephenson, Kathryn E; Peron, Jean Pierre S; Zanotto, Paolo M de A; Misamore, Johnathan; Finneyfrock, Brad; Lewis, Mark G; Alter, Galit; Modjarrad, Kayvon; Jarman, Richard G; Eckels, Kenneth H; Michael, Nelson L; Thomas, Stephen J; Barouch, Dan H

    2016-09-09

    Zika virus (ZIKV) is responsible for a major ongoing epidemic in the Americas and has been causally associated with fetal microcephaly. The development of a safe and effective ZIKV vaccine is therefore an urgent global health priority. Here we demonstrate that three different vaccine platforms protect against ZIKV challenge in rhesus monkeys. A purified inactivated virus vaccine induced ZIKV-specific neutralizing antibodies and completely protected monkeys against ZIKV strains from both Brazil and Puerto Rico. Purified immunoglobulin from vaccinated monkeys also conferred passive protection in adoptive transfer studies. A plasmid DNA vaccine and a single-shot recombinant rhesus adenovirus serotype 52 vector vaccine, both expressing ZIKV premembrane and envelope, also elicited neutralizing antibodies and completely protected monkeys against ZIKV challenge. These data support the rapid clinical development of ZIKV vaccines for humans.

  19. Wearable Device Control Platform Technology for Network Application Development

    Directory of Open Access Journals (Sweden)

    Heejung Kim

    2016-01-01

    Full Text Available Application development platform is the most important environment in IT industry. There are a variety of platforms. Although the native development enables application to optimize, various languages and software development kits need to be acquired according to the device. The coexistence of smart devices and platforms has rendered the native development approach time and cost consuming. Cross-platform development emerged as a response to these issues. These platforms generate applications for multiple devices based on web languages. Nevertheless, development requires additional implementation based on a native language because of the coverage and functions of supported application programming interfaces (APIs. Wearable devices have recently attracted considerable attention. These devices only support Bluetooth-based interdevice communication, thereby making communication and device control impossible beyond a certain range. We propose Network Application Agent (NetApp-Agent in order to overcome issues. NetApp-Agent based on the Cordova is a wearable device control platform for the development of network applications, controls input/output functions of smartphones and wearable/IoT through the Cordova and Native API, and enables device control and information exchange by external users by offering a self-defined API. We confirmed the efficiency of the proposed platform through experiments and a qualitative assessment of its implementation.

  20. A Cross-Platform Tactile Capabilities Interface for Humanoid Robots

    Directory of Open Access Journals (Sweden)

    Jie eMa

    2016-04-01

    Full Text Available This article presents the core elements of a cross-platform tactile capabilities interface (TCI for humanoid arms. The aim of the interface is to reduce the cost of developing humanoid robot capabilities by supporting reuse through cross-platform deployment. The article presents a comparative analysis of existing robot middleware frameworks, as well as the technical details of the TCI framework that builds on the the existing YARP platform. The TCI framework currently includes robot arm actuators with robot skin sensors. It presents such hardware in a platform independent manner, making it possible to write robot control software that can be executed on different robots through the TCI frameworks. The TCI framework supports multiple humanoid platforms and this article also presents a case study of a cross-platform implementation of a set of tactile protective withdrawal reflexes that have been realised on both the Nao and iCub humanoid robot platforms using the same high-level source code.

  1. Communications payloads for geostationary platforms

    Science.gov (United States)

    Fordyce, S. W.

    1978-01-01

    Trends in communication satellites show increasing reuse of the frequency spectrum through multiple spot beams and orthogonal polarization, as well as consortia operation. Current reliance on orbital arc separation for frequency reuse may be inadequate for the projected traffic growth and the orbital slotting proposals before the ITU. This paper notes that cost advantages can accrue through common use of spacecraft subsystems and multiple users' platforms aboard a common geostationary platform. The rationale for such platforms is described and potential payloads are suggested.

  2. Utilizing platforms in industrialized construction

    DEFF Research Database (Denmark)

    Bonev, Martin; Wörösch, Michael; Hvam, Lars

    2015-01-01

    construction companies. A promising approach adapted by operations management and design theory regards individual building projects as the adjustment and recombination of components and processes from a set of predefined platforms, while configuration systems assure feasible building solutions. Design...... methods map structural platform characteristics so as to balance commonality and distinctiveness. Originality/value – This paper proposes a general theory of platform-based development and execution in the industrialised construction sector, which goes beyond concurrent approaches of standardising...

  3. Business and IT Capabilities for Cloud Platform Success

    DEFF Research Database (Denmark)

    Hahn, Christopher; Huntgeburth, Jan; Winkler, Till J.

    2016-01-01

    the complementary role of the three proposed business capabilities (incentives and rules, ecosystem marketing and sales, partner development and support) for relevant value creation and appropriation mechanisms. In addition to providing a capability framework catered to the cloud platform context, our findings......) instantiates Rai and Tang’s (2014) framework of dyadic IT and network IT capabilities for a cloud platform context and extends it by exploring previously undertheorized cloud platform business capabilities. We further build on this extended framework by employing a configurational perspective to elucidate...

  4. Standard Interfaces for Open Source Infrastructure as a Service Platforms

    Directory of Open Access Journals (Sweden)

    Andrei IONESCU

    2015-01-01

    Full Text Available To reduce vendor lock-in and fragmentation and to evolve into a transparent platform, IaaS platforms must adhere to open standards. All the major open source IaaS Platforms offer interfaces compatible with the de facto standards but mostly lacks support for the de jure, open efforts of standardization. Available implementations of open standards are not part of their main development efforts. More development resources as well as consolidation of open standards are needed to achieve increased portability and interoperability.

  5. Web Platform Application

    Energy Technology Data Exchange (ETDEWEB)

    Paulsworth, Ashley [Sunvestment Group, Frederick, MD (United States); Kurtz, Jim [Sunvestment Group, Frederick, MD (United States); Brun de Pontet, Stephanie [Sunvestment Group, Frederick, MD (United States)

    2016-06-15

    Sunvestment Energy Group (previously called Sunvestment Group) was established to create a web application that brings together site hosts, those who will obtain the energy from the solar array, with project developers and funders, including affinity investors. Sunvestment Energy Group (SEG) uses a community-based model that engages with investors who have some affinity with the site host organization. In addition to a financial return, these investors receive non-financial value from their investments and are therefore willing to offer lower cost capital. This enables the site host to enjoy more savings from solar through these less expensive Community Power Purchase Agreements (CPPAs). The purpose of this award was to develop an online platform to bring site hosts and investors together virtually.

  6. The Creative Soccer Platform

    DEFF Research Database (Denmark)

    Johan Torp Rasmussen, Ludvig; Østergaard, Lars Domino

    2016-01-01

    Creativity is essential in soccer due to the unpredictable and complex situations occurring in the game, where stereotypical play gradually loses its efficiency. Further, creativity is an important psychological factor for the development of soccer expertise, and valuing creativity increases...... satisfaction and well-being. Although creative players are highly desired by coaches, the subject of cultivating creativity is mostly ignored and traditional training settings may even hamper the players' creativity. The purpose of this article is to introduce a novel approach for enhancing soccer players......' creativity, The Creative Soccer Platform (TCSP), and to demonstrate the implications of applying it in youth soccer practice, by means of soccer-specific creativity exercises. TCSP encompasses four theoretically based didactic principles (task focus, parallel thinking, horizontal thinking, and no experienced...

  7. A Short Survey on the State of the Art in Architectures and Platforms for Large Scale Data Analysis and Knowledge Discovery from Data

    Energy Technology Data Exchange (ETDEWEB)

    Begoli, Edmon [ORNL

    2012-01-01

    Intended as a survey for practicing architects and researchers seeking an overview of the state-of-the-art architectures for data analysis, this paper provides an overview of the emerg- ing data management and analytic platforms including par- allel databases, Hadoop-based systems, High Performance Computing (HPC) platforms and platforms popularly re- ferred to as NoSQL platforms. Platforms are presented based on their relevance, analysis they support and the data organization model they support.

  8. Robotic platform for traveling on vertical piping network

    Science.gov (United States)

    Nance, Thomas A; Vrettos, Nick J; Krementz, Daniel; Marzolf, Athneal D

    2015-02-03

    This invention relates generally to robotic systems and is specifically designed for a robotic system that can navigate vertical pipes within a waste tank or similar environment. The robotic system allows a process for sampling, cleaning, inspecting and removing waste around vertical pipes by supplying a robotic platform that uses the vertical pipes to support and navigate the platform above waste material contained in the tank.

  9. Using and Designing Platforms for In Vivo Education Experiments

    OpenAIRE

    Williams, Joseph Jay; Ostrow, Korinn; Xiong, Xiaolu; Glassman, Elena; Kim, Juho; Maldonado, Samuel G.; Li, Na; Reich, Justin; Hefferman, Neil

    2015-01-01

    In contrast to typical laboratory experiments, the everyday use of online educational resources by large populations and the prevalence of software infrastructure for A/B testing leads us to consider how platforms can embed in vivo experiments that do not merely support research, but ensure practical improvements to their educational components. Examples are presented of randomized experimental comparisons conducted by subsets of the authors in three widely used online educational platforms K...

  10. Product Platform Screening at LEGO

    DEFF Research Database (Denmark)

    Mortensen, Niels Henrik; Steen Jensen, Thomas; Nielsen, Ole Fiil

    2012-01-01

    Product platforms offer great benefits to companies developing new products in highly competitive markets. Literature describes how a single platform can be designed from a technical point of view, but rarely mentions how the process begins. How do companies identify possible platform candidates...... after a few changes had been applied to the initial process layout. This case study shows how companies must focus on a limited selection of simultaneous projects in order to keep focus. Primary stakeholders must be involved from the very beginning, and short presentations of the platform concepts...

  11. Instrument platforms for thin-layer chromatography.

    Science.gov (United States)

    Bernard-Savary, Pierre; Poole, Colin F

    2015-11-20

    High performance column and thin-layer chromatography are both instrumental techniques but differ in that column chromatography requires a fully integrated instrument platform with high pressure capability while for thin-layer chromatography separate devices are used for each unit operation, usually at or close to atmospheric pressure, and afford higher flexibility supporting on-line or off-line operation. The unit operations of thin-layer chromatography are defined as sample application, development and evaluation with derivatization as an optional step. The diversity of equipment for each operation contributes to the flexibility of analysis by thin-layer chromatography and supports manual, semi-automated or full-automation of the separation process. Instrument platforms are more than a convenience as they affect performance, repeatability, sample detectability, and time management. The current trend in thin-layer chromatography is to make the unit operations independent of the user so that analysts can perform other tasks while each step is performed. In addition, in thin-layer chromatography it is general practice to separate several samples simultaneously, and instrument platforms are required to accommodate this feature. In this article, we review contemporary instrumentation employed in thin-layer chromatography for sample application, development, derivatization, photodocumentation, densitometric evaluation, and hyphenation with spectroscopic detectors with an emphasis on the variety and performance of commercially available systems. Some suggestions for best practices and avoidance of common mistakes are included. Copyright © 2015 Elsevier B.V. All rights reserved.

  12. Toward an E-Government Semantic Platform

    Science.gov (United States)

    Sbodio, Marco Luca; Moulin, Claude; Benamou, Norbert; Barthès, Jean-Paul

    This chapter describes the major aspects of an e-government platform in which semantics underpins more traditional technologies in order to enable new capabilities and to overcome technical and cultural challenges. The design and development of such an e-government Semantic Platform has been conducted with the financial support of the European Commission through the Terregov research project: "Impact of e-government on Territorial Government Services" (Terregov 2008). The goal of this platform is to let local government and government agencies offer online access to their services in an interoperable way, and to allow them to participate in orchestrated processes involving services provided by multiple agencies. Implementing a business process through an electronic procedure is indeed a core goal in any networked organization. However, the field of e-government brings specific constraints to the operations allowed in procedures, especially concerning the flow of private citizens' data: because of legal reasons in most countries, such data are allowed to circulate only from agency to agency directly. In order to promote transparency and responsibility in e-government while respecting the specific constraints on data flows, Terregov supports the creation of centrally controlled orchestrated processes; while the cross agencies data flows are centrally managed, data flow directly across agencies.

  13. Platform Performance and Challenges - using Platforms in Lego Company

    DEFF Research Database (Denmark)

    Munk, Lone; Mortensen, Niels Henrik

    2009-01-01

    This article studies the performance and challenges of using nine implemented product platforms in LEGO Company. Most of these do produce results, but do not meet their goals due to challenges in their usage in the daily product. The main challenges are that the platforms are not being used...

  14. Implementing Open Source Platform for Education Quality Enhancement in Primary Education: Indonesia Experience

    Science.gov (United States)

    Kisworo, Marsudi Wahyu

    2016-01-01

    Information and Communication Technology (ICT)-supported learning using free and open source platform draws little attention as open source initiatives were focused in secondary or tertiary educations. This study investigates possibilities of ICT-supported learning using open source platform for primary educations. The data of this study is taken…

  15. Speeding up Derivative Configuration from Product Platforms

    Directory of Open Access Journals (Sweden)

    Ruben Heradio

    2014-06-01

    Full Text Available To compete in the global marketplace, manufacturers try to differentiate their products by focusing on individual customer needs. Fulfilling this goal requires that companies shift from mass production to mass customization. Under this approach, a generic architecture, named product platform, is designed to support the derivation of customized products through a configuration process that determines which components the product comprises. When a customer configures a derivative, typically not every combination of available components is valid. To guarantee that all dependencies and incompatibilities among the derivative constituent components are satisfied, automated configurators are used. Flexible product platforms provide a big number of interrelated components, and so, the configuration of all, but trivial, derivatives involves considerable effort to select which components the derivative should include. Our approach alleviates that effort by speeding up the derivative configuration using a heuristic based on the information theory concept of entropy.

  16. 区域卫生信息平台支持决策系统设计思路%Design of Decision Support System of Regional Health Information Platform

    Institute of Scientific and Technical Information of China (English)

    李军

    2012-01-01

    Demand analysis plays an important role in the process of system analysis and design, which is one of the key factors of success. In order to design a decision support system to meet the needs for health management, the paper analyzers the uses and department organization structure, and introduces the information content and information source for the health management decision-making. Finally, it discusses the decision-making function requirement of system.%为提高卫生管理支持决策水平和效率,对卫生行政管理人员提供全方位的卫生统计信息,在区域卫生信息平台上设计了支持决策子系统.

  17. Rapid prototyping of robotic platforms

    CSIR Research Space (South Africa)

    De Ronde, Willis

    2016-11-01

    Full Text Available Building a robotic platform from raw materials can take anything from a few weeks to a few years to complete, depending on the complexity and size of the platform. This paper aims to introduce a novel approach of using abrasive waterjet machining...

  18. Preparing for a Product Platform

    DEFF Research Database (Denmark)

    Fiil-Nielsen, Ole; Munk, Lone; Mortensen, Niels Henrik

    2005-01-01

    they lead to increased sales due to more customized product as well as decreased costs due to reuse, making a product development platform a very profitable strategy for product developing companies. A successful implementation of a product development platform is not straightforward though...

  19. Product Platform Screening at LEGO

    DEFF Research Database (Denmark)

    Mortensen, Niels Henrik; Steen Jensen, Thomas; Nielsen, Ole Fiil

    2012-01-01

    Product platforms offer great benefits to companies developing new products in highly competitive markets. Literature describes how a single platform can be designed from a technical point of view, but rarely mentions how the process begins. How do companies identify possible platform candidates......, and how do they assess if these candidates have enough potential to be worth implementing? Danish toy manufacturer LEGO has systematically gone through this process twice. The first time the results were poor; almost all platform candidates failed. The second time, though, has been largely successful...... after a few changes had been applied to the initial process layout. This case study shows how companies must focus on a limited selection of simultaneous projects in order to keep focus. Primary stakeholders must be involved from the very beginning, and short presentations of the platform concepts...

  20. ADAPTABLE ALTERNATE REALITY GAMES PLATFORM

    Directory of Open Access Journals (Sweden)

    Liviu-Adrian Cotfas

    2013-12-01

    Full Text Available In this paper, we present an alternate reality games platform that facilitates the creation of ARG projects with different themes and sizes. The platform is well integrated with the most important social media networks, thus facilitating both the involvement of the public and the creation of a more engaging interaction for the participants. A cloud-based architecture was used in order to allow the platform to easily accommodate projects of various sizes and to provide a good level of scalability. The platform is fully localizable in any language and multiple languages can be used at once to create projects that target users from different countries. An initial project that uses gamification to create an immersive learning environment has been created around the developed platform. The project combines professional and public feedback in order to provide an enhanced learning experience.

  1. 卫生信息平台管理决策支持系统需求分析%Demand Analysis of Decision Support System about Health Information Platform

    Institute of Scientific and Technical Information of China (English)

    王春容; 李道苹

    2012-01-01

    需求分析在系统分析和设计过程中占有重要地位,是决定系统开发能否成功的关键因素之一.为设计出满足卫生管理人员需求的决策支持系统,对系统用户和部门组织结构等进行了分析,详细介绍了卫生管理决策所需的信息内容及信息来源,并对系统的决策功能需求进行了探讨.%Demand analysis plays an important role in the process of system analysis and design, which is one of the key factors of success. In order to design a decision support system to meet the needs for health management, the paper analyzes the users and department organization structure, and introduces the information content and information source for the health management decision-making- Finally, it discusses the decision-making function requirement of system.

  2. The research and development of platform of process instrument and control

    Science.gov (United States)

    Gao, Dong; Xu, Xin; Yin, Jianjin; Zhang, Hongyu; Zhang, Beike

    2017-09-01

    Process instrument and control experiment platform was researched, designed and developed. The controlled object was extracted from typical unit of process industry. In the platform the water and air were used for heat exchanging and recycling. The water and air can be recycled. The platform is easy to maintain. The real industrial instruments and distribute control system were used. The platform is close to the real industry. Many experiments about instrument and control can be supported. Good teaching and experiment environment can be supplied by the platform for the courses of process control and measuring instrument. The teaching standard can be improved.

  3. Gesture therapy: an upper limb virtual reality-based motor rehabilitation platform.

    Science.gov (United States)

    Sucar, Luis Enrique; Orihuela-Espina, Felipe; Velazquez, Roger Luis; Reinkensmeyer, David J; Leder, Ronald; Hernández-Franco, Jorge

    2014-05-01

    Virtual reality platforms capable of assisting rehabilitation must provide support for rehabilitation principles: promote repetition, task oriented training, appropriate feedback, and a motivating environment. As such, development of these platforms is a complex process which has not yet reached maturity. This paper presents our efforts to contribute to this field, presenting Gesture Therapy, a virtual reality-based platform for rehabilitation of the upper limb. We describe the system architecture and main features of the platform and provide preliminary evidence of the feasibility of the platform in its current status.

  4. Paper based electronics platform

    KAUST Repository

    Nassar, Joanna Mohammad

    2017-07-20

    A flexible and non-functionalized low cost paper-based electronic system platform fabricated from common paper, such as paper based sensors, and methods of producing paper based sensors, and methods of sensing using the paper based sensors are provided. A method of producing a paper based sensor can include the steps of: a) providing a conventional paper product to serve as a substrate for the sensor or as an active material for the sensor or both, the paper product not further treated or functionalized; and b) applying a sensing element to the paper substrate, the sensing element selected from the group consisting of a conductive material, the conductive material providing contacts and interconnects, sensitive material film that exhibits sensitivity to pH levels, a compressible and/or porous material disposed between a pair of opposed conductive elements, or a combination of two of more said sensing elements. The method of sensing can further include measuring, using the sensing element, a change in resistance, a change in voltage, a change in current, a change in capacitance, or a combination of any two or more thereof.

  5. Plat_Forms -- a contest: The web development platform comparison

    CERN Document Server

    Prechelt, Lutz

    2008-01-01

    "Plat_Forms" is a competition in which top-class teams of three programmers compete to implement the same requirements for a web-based system within 30 hours, each team using a different technology platform (Java EE, .NET, PHP, Perl, Python, or Ruby on Rails). The results will provide new insights into the real (rather than purported) pros, cons, and emergent properties of each platform. The evaluation will analyze many aspects of each solution, both external (usability, functionality, reliability, performance, etc.) and internal (structure, understandability, flexibility, etc.).

  6. Platform projections, compilers, interpreters and portability

    NARCIS (Netherlands)

    Bergstra, J.A.; Loots, M.E.

    1999-01-01

    Platform projection semantics extends projection semantics by means of the encapsulation of a processor used for program execution. Platform projection semantics abstracts from platform specific details. For a given program its platform projection semantics may be platform-independent. Two forms

  7. Concept and architecture of the RHIC LLRF upgrade platform

    Energy Technology Data Exchange (ETDEWEB)

    Smith, K.S.; Hayes, T.; Severino, F.

    2011-03-28

    The goal of the RHIC LLRF upgrade has been the development of a stand alone, generic, high performance, modular LLRF control platform, which can be configured to replace existing systems and serve as a common platform for all new RF systems. The platform is also designed to integrate seamlessly into a distributed network based controls infrastructure, be easy to deploy, and to be useful in a variety of digital signal processing and data acquisition roles. Reuse of hardware, software and firmware has been emphasized to minimize development effort and maximize commonality of system components. System interconnection, synchronization and scaling are facilitated by a deterministic, high speed serial timing and data link, while standard intra and inter chassis communications utilize high speed, non-deterministic protocol based serial links. System hardware configuration is modular and flexible, based on a combination of a main carrier board which can host up to six custom or commercial daughter modules as required to implement desired functionality. This paper will provide an overview of the platform concept, architecture, features and benefits. The RHIC LLRF Upgrade Platform has been developed with the goal of providing a flexible, modular and scalable architecture which will support our current applications and satisfy new ones for the foreseeable future. The platform has been recently commissioned at both RHIC and the RHIC EBIS injector. To date the platform has demonstrated its versatility and utility, meeting the design goals as originally defined.

  8. Beginning Java- me platform

    CERN Document Server

    Rischpater, Ray

    2008-01-01

    Empowering developers with the flexibility and power to start building Java applications for their Java-enabled mobile device or cell phone, this book covers sound HTTPS support, user interface API enhancements, the Mobile Media API, the Game API, and more.

  9. Governing Logistics Information Platforms

    NARCIS (Netherlands)

    Klievink, A.J.; Aldewereld, H.M.; Knol, A.; Tan, Y.H.

    2014-01-01

    The Extended Single Window (ESW) project aims to support goods flows by Information and Communication Technology (ICT). Specifically, the project takes the concept of Single Windows (often used in the sense that governments offer a single portal or interface to which businesses can submit informatio

  10. Governing Logistics Information Platforms

    NARCIS (Netherlands)

    Klievink, A.J.; Aldewereld, H.M.; Knol, A.; Tan, Y.H.

    2014-01-01

    The Extended Single Window (ESW) project aims to support goods flows by Information and Communication Technology (ICT). Specifically, the project takes the concept of Single Windows (often used in the sense that governments offer a single portal or interface to which businesses can submit

  11. Governing Logistics Information Platforms

    NARCIS (Netherlands)

    Klievink, A.J.; Aldewereld, H.M.; Knol, A.; Tan, Y.H.

    2014-01-01

    The Extended Single Window (ESW) project aims to support goods flows by Information and Communication Technology (ICT). Specifically, the project takes the concept of Single Windows (often used in the sense that governments offer a single portal or interface to which businesses can submit informatio

  12. Advances in product family and product platform design methods & applications

    CERN Document Server

    Jiao, Jianxin; Siddique, Zahed; Hölttä-Otto, Katja

    2014-01-01

    Advances in Product Family and Product Platform Design: Methods & Applications highlights recent advances that have been made to support product family and product platform design and successful applications in industry. This book provides not only motivation for product family and product platform design—the “why” and “when” of platforming—but also methods and tools to support the design and development of families of products based on shared platforms—the “what”, “how”, and “where” of platforming. It begins with an overview of recent product family design research to introduce readers to the breadth of the topic and progresses to more detailed topics and design theory to help designers, engineers, and project managers plan, architect, and implement platform-based product development strategies in their companies. This book also: Presents state-of-the-art methods and tools for product family and product platform design Adopts an integrated, systems view on product family and pro...

  13. Vertical Relationships within Platform Marketplaces

    Directory of Open Access Journals (Sweden)

    Mark J. Tremblay

    2016-07-01

    Full Text Available In two-sided markets a platform allows consumers and sellers to interact by creating sub-markets within the platform marketplace. For example, Amazon has sub-markets for all of the different product categories available on its site, and smartphones have sub-markets for different types of applications (gaming apps, weather apps, map apps, ridesharing apps, etc.. The network benefits between consumers and sellers depend on the mode of competition within the sub-markets: more competition between sellers lowers product prices, increases the surplus consumers receive from a sub-market, and makes platform membership more desirable for consumers. However, more competition also lowers profits for a seller which makes platform membership less desirable for a seller and reduces seller entry and the number of sub-markets available on the platform marketplace. This dynamic between seller competition within a sub-market and agents’ network benefits leads to platform pricing strategies, participation decisions by consumers and sellers, and welfare results that depend on the mode of competition. Thus, the sub-market structure is important when investigating platform marketplaces.

  14. Towards a Wireless Sensor Platform for Energy Efficient Building Operation

    Institute of Scientific and Technical Information of China (English)

    Karsten Menzel; Dirk Pesch; Brendan O'Flynn; Marcus Keane; Cian O'Mathuna

    2008-01-01

    Currently, the IT-support for energy performance rating of buildings is insufficient. So-called IT-platforms often "built" of an ad-hoc, inconsistent combination of off-the-shelf building management compo-nents, distributed data metering equipment and several monitoring software tools. A promising approach to achieve consistent, holistic performance data management is the implementation of an integrated, modular wireless sensor platform. This paper presents an approach of how wireless sensors can be seamlessly inte-grated into existing and future intelligent building management systems supporting improved building per-formance and diagnostics with an emphasis on energy management.

  15. Lack of experimental evidence to support mcr-1-positive escherichia coli strain selection during oral administration of colistin at recommended and higher dose given by gavage in weaned piglets.

    Science.gov (United States)

    Viel, Alexis; Henri, Jérôme; Perrin-Guyomard, Agnès; Laroche, Julian; Couet, William; Grégoire, Nicolas; Laurentie, Michel

    2017-06-28

    In this study, we assessed the selective effect of colistin orally administered to healthy weaned piglets harbouring an intestinal mcr-1-positive Escherichia coli strain. Maximum recommended dose and a higher dose often used in European pig farms were given by gavage. No selection of the mcr-1-positive strain was observed in our controlled conditions whatever the dose. Further investigations in real farming conditions seem necessary. Copyright © 2017 Elsevier B.V. and International Society of Chemotherapy. All rights reserved.

  16. Platform Architecture for Decentralized Positioning Systems

    Directory of Open Access Journals (Sweden)

    Zakaria Kasmi

    2017-04-01

    Full Text Available A platform architecture for positioning systems is essential for the realization of a flexible localization system, which interacts with other systems and supports various positioning technologies and algorithms. The decentralized processing of a position enables pushing the application-level knowledge into a mobile station and avoids the communication with a central unit such as a server or a base station. In addition, the calculation of the position on low-cost and resource-constrained devices presents a challenge due to the limited computing, storage capacity, as well as power supply. Therefore, we propose a platform architecture that enables the design of a system with the reusability of the components, extensibility (e.g., with other positioning technologies and interoperability. Furthermore, the position is computed on a low-cost device such as a microcontroller, which simultaneously performs additional tasks such as data collecting or preprocessing based on an operating system. The platform architecture is designed, implemented and evaluated on the basis of two positioning systems: a field strength system and a time of arrival-based positioning system.

  17. A novel platform device for rodent echocardiography.

    Science.gov (United States)

    Kutschka, Ingo; Sheikh, Ahmad Y; Sista, Ramachandra; Hendry, Stephen L; Chun, Hyung J; Hoyt, Grant; Kutschka, Werner; Pelletier, Marc P; Quertermous, Tom; Wu, Joseph C; Robbins, Robert C

    2007-06-06

    Acquisition of echocardiographic data from rodents is subject to wide variability due to variations in technique. We hypothesize that a dedicated imaging platform can aid in standardization of technique and improve the quality of images obtained. We constructed a device consisting of a boom-mounted steel platform frame (25 x 35 x 3 cm) on which a transparent polyethylene membrane is mounted. The animal is placed onto the membrane and receives continual inhaled anesthesia via an integrated port. The membrane allows for probe positioning from beneath the animal to obtain standard echo-views in left lateral decubitus or prone positions. The frame can be set at any desired angle ranging from 0 to 360 degrees along either the long or short axis. Adult male Sprague-Dawley rats (n = 5) underwent echocardiography (General Electric, Vivid 7, 14 MHz) using the platform. The device allowed for optimal positioning of animals for a variety of standard echocardiographic measurements. Evaluations among all animals showed minimal variability between two different operators and time points. We tested the feasibility of the device for supporting the assessment of cardiac function in a disease model by evaluating a separate cohort of adult male spontaneously hypertensive rats (n = 5) that underwent left anterior descending coronary artery ligation. Serial echocardiography demonstrated statistically significant decreases of fractional shortening and ejection fraction (p rats. Future studies will focus on improving this technology to allow for standardized high-throughput echocardiographic analysis in small animal models of disease.

  18. Platform Architecture for Decentralized Positioning Systems.

    Science.gov (United States)

    Kasmi, Zakaria; Norrdine, Abdelmoumen; Blankenbach, Jörg

    2017-04-26

    A platform architecture for positioning systems is essential for the realization of a flexible localization system, which interacts with other systems and supports various positioning technologies and algorithms. The decentralized processing of a position enables pushing the application-level knowledge into a mobile station and avoids the communication with a central unit such as a server or a base station. In addition, the calculation of the position on low-cost and resource-constrained devices presents a challenge due to the limited computing, storage capacity, as well as power supply. Therefore, we propose a platform architecture that enables the design of a system with the reusability of the components, extensibility (e.g., with other positioning technologies) and interoperability. Furthermore, the position is computed on a low-cost device such as a microcontroller, which simultaneously performs additional tasks such as data collecting or preprocessing based on an operating system. The platform architecture is designed, implemented and evaluated on the basis of two positioning systems: a field strength system and a time of arrival-based positioning system.

  19. Design and construction of translational medicine platform for urologic oncology.

    Science.gov (United States)

    Xu, Yong; Yang, Kuo

    2012-03-01

    Translational medicine is a new medical model which focus on overcoming the serious imbalance among the basic research, its clinical and public health application. Its core is to establish effective ties among basic medical researchers, public health workers and doctors who know the needs of patients, particularly translating the molecular medical research results to suitable disease prevention, diagnosis, treatment and prevention methods effectively. This paper discusses the design and construction of the translational medicine platform for urologic system tumors. However, there is no draw on the precedent, it is a challenging project to create such a complicated platform and make it running smoothly and effectively. Based on the Tianjin Translational Medicine Platform for Urologic Oncology (TTMPUO) which had been established in support of Tianjin Science and Technology Commission, this paper will focus on describing the design ideas and the essential parts of the platform.

  20. An Open Platform for Full Body Interactive Sonification Exergames

    Directory of Open Access Journals (Sweden)

    Simone Ghisio

    2015-08-01

    Full Text Available This paper addresses the use of a remote interactive platform to support home-based rehabilitation for children with motor and cognitive impairment. The interaction between user and platform is achieved on customizable full-body interactive serious games (exergames. These exergames perform real-time analysis of multimodal signals to quantify movement qualities and postural attitudes. Interactive sonification of movement is then applied for providing a real-time feedback based on “aesthetic resonance” and engagement of the children. The games also provide log file recordings therapists can use to assess the performance of the children and the effectiveness of the games. The platform allows the customization of the games to address the children’s needs. The platform is based on the EyesWeb XMI software, and the games are designed for home usage, based on Kinect for Xbox One and simple sensors including 3-axis accelerometers available in low-cost Android smartphones.