WorldWideScience

Sample records for platform rcp framework

  1. Towards a Framework of Digital Platform Competition

    DEFF Research Database (Denmark)

    Kazan, Erol; Tan, Chee-Wee; Lim, Eric T. K.

    2016-01-01

    This paper advances a framework for examining the competitive principles of mobile payment platforms. We postulate that the strategic interplay of platform layers will drive the competitive dynamics of platform-driven ubiquitous systems. This framework has been employed in a comparative case study...

  2. Towards a Framework of Digital Platform Disruption

    DEFF Research Database (Denmark)

    Kazan, Erol; Tan, Chee-Wee; Lim, Eric T. K.

    2014-01-01

    Digital platforms are disruptive information technology (IT) artifacts that erode conventional business logic associated with traditional market structures. This paper presents a framework for examining the disruptive potential of digital platforms whereby we postulate that the strategic interplay...... of governance regimes and platform layers is deterministic of whether disruptive derivatives are permitted to flourish. This framework has been employed in a comparative case study between centralized (i.e., PayPal) and decentralized (i.e., Coinkite) digital payment platforms to illustrate its applicability...... and yield propositions on the nature and impact of digital platform disruptions. Preliminary findings indicate that centralized digital platforms attempt to create unique configurals to obtain monopolistic power by tightly coupling platform layers, which are difficult to replicate. Conversely, decentralized...

  3. MP-RCP:ACHIEVING FAST RECOVERY OF iBGP USING ROUTE CONTROL PLATFORM%MP-RCP:基于RCP的快速恢复iBGP协议

    Institute of Scientific and Technical Information of China (English)

    程柏林; 胡乔林; 陈新; 吕树君

    2014-01-01

    Mechanism of iBGP single best path propagation may prevent the router from acquiring diverse paths,which results in connection disruption and inter-domain churn in the scene of transient link.MP-RCP optimises the route control platform (RCP)to reduce the session numbers and configuration complexity,makes use of global visible routes to compute and disseminate multiple paths for each router.When a router detects the failure in best path,the router encapsulates the packets and forwards them to the backup path to avoid the connection disruption.MP-RCP also separates the failure detection and processing in order to prevent the frequent convergence triggered by transient failures,which reduces the inter-domain disturbance.It is proved through Abilene topology and the experiment of topology generation that the MP-RCP structure reduces the forwarding disruption and inter-domain churn effectively.%iBGP 传播单条最佳路径机制不能保证路由器获得多样性路径,造成链路瞬时故障场景下连接中断及域间扰动。MP-RCP(MultiPath Route Control Platform)优化路由控制平台RCP以降低会话数量及配置复杂性,利用全局可视路由对每台路由器计算、分发多路径。当路由器检测到最佳路径失效后,将报文封装转发到备份路径中避免连接中断;MP-RCP中将失效检测、处理进行分离以避免瞬时故障引起的频繁收敛,从而降低了域间扰动。通过使用Abilene拓扑以及生成拓扑的实验证明了MP-RCP结构能有效避免转发中断和域间扰动。

  4. Towards a Market Entry Framework for Digital Payment Platforms

    DEFF Research Database (Denmark)

    Kazan, Erol; Damsgaard, Jan

    2016-01-01

    This study presents a framework to understand and explain the design and configuration of digital payment platforms and how these platforms create conditions for market entries. By embracing the theoretical lens of platform envelopment, we employed a multiple and comparative-case study...... in a European setting by using our framework as an analytical lens to assess market-entry conditions. We found that digital payment platforms have acquired market entry capabilities, which is achieved through strategic platform design (i.e., platform development and service distribution) and technology design...... (i.e., issuing evolutionary and revolutionary payment instruments). The studied cases reveal that digital platforms leverage payment services as a mean to bridge and converge core and adjacent platform markets. In so doing, platform envelopment strengthens firms’ market position in their respective...

  5. Towards a Market Entry Framework for Digital Payment Platforms

    DEFF Research Database (Denmark)

    Kazan, Erol; Damsgaard, Jan

    2016-01-01

    (i.e., issuing evolutionary and revolutionary payment instruments). The studied cases reveal that digital platforms leverage payment services as a mean to bridge and converge core and adjacent platform markets. In so doing, platform envelopment strengthens firms’ market position in their respective......This study presents a framework to understand and explain the design and configuration of digital payment platforms and how these platforms create conditions for market entries. By embracing the theoretical lens of platform envelopment, we employed a multiple and comparative-case study...... in a European setting by using our framework as an analytical lens to assess market-entry conditions. We found that digital payment platforms have acquired market entry capabilities, which is achieved through strategic platform design (i.e., platform development and service distribution) and technology design...

  6. Research on the Geological Monitoring Data Visualization Application Based on Eclipse RCP framework%基于Eclipse RCP框架的地质监测数据可视化应用研究

    Institute of Scientific and Technical Information of China (English)

    杨攀

    2015-01-01

    基于Eclilpse RCP的可视化技术和面向服务的SOA架构,分析了传统地质灾害监测数据的特点,针对地质灾害监测数据可视化的需求,结合Eclipse RCP的优点,构建了一种地质灾害监测数据的集成框架,实现了地质灾害监测数据的可视化显示。%Eclipse RCP technology and service-oriented architecture (SOA) software mode are used to analyze characteristics of the geological disaster data. Based on geological disaster monitoring data visualization need, combing with the advantages of the Eclipse RCP, this paper constructs an integrated framework of the geological disaster monitoring data and realizes the visualization of geological disaster monitoring data.

  7. Plant DNA barcoding and framework for biodiversity data sharing platform

    Directory of Open Access Journals (Sweden)

    Chunxia Zeng

    2014-05-01

    Full Text Available DNA barcoding technology provides an opportunity for rapid, accurate, and standardized species-level identification using short DNA sequences. This method speeds up species identification and classification, and presents a new tool for the management, conservation and sustainable development of biodiversity at a global level. Due to improvements in plant barcode database availability and functionality, it is becoming feasible to meet increasing demands for biodiversity information. A framework is needed for a barcoding server platform that utilizes, integrates, and shares among different data types. Such a platform would be an important step towards enabling the public to rapidly identify species and acquire species-related digital information. In this paper, we review current progress on plant DNA barcoding. Secondly, we summarize the current status of, and identify bottlenecks for, plant DNA barcode reference libraries specifically. Thirdly, in the Big Data era, it is indispensable to manage and make good use of massive amounts of plant information. We provide the following suggestions for the framework of server platform: (1 metadata should be substantial, accurate and correlative; (2 data should be normalized; (3 query entrance is convenient, efficient, easy to manage, and available for large-scale data sharing and global communication.

  8. A Framework of Information Service Platform in E-Government

    Institute of Scientific and Technical Information of China (English)

    GAN Renchu; DU Ding

    2004-01-01

    For exchanging and sharing information and services in e-government, a framework of information service platform (ISP) is presented. The multi-layer architecture of the ISP is introduced They are: user's requirement layer, business service layer, business process layer, business function layer and data layer. The lower layers are based on the architecture of web services and the upper layers are related to the institutional and organizational issues. In order to deal with the variation of user's requirements and changing environment, the matching and mapping processes with adaptive mechanism are illustrated.

  9. Ambient Assisted Living Healthcare Frameworks, Platforms, Standards, and Quality Attributes

    Directory of Open Access Journals (Sweden)

    Mukhtiar Memon

    2014-03-01

    Full Text Available Ambient Assisted Living (AAL is an emerging multi-disciplinary field aiming at exploiting information and communication technologies in personal healthcare and telehealth systems for countering the effects of growing elderly population. AAL systems are developed for personalized, adaptive, and anticipatory requirements, necessitating high quality-of-service to achieve interoperability, usability, security, and accuracy. The aim of this paper is to provide a comprehensive review of the AAL field with a focus on healthcare frameworks, platforms, standards, and quality attributes. To achieve this, we conducted a literature survey of state-of-the-art AAL frameworks, systems and platforms to identify the essential aspects of AAL systems and investigate the critical issues from the design, technology, quality-of-service, and user experience perspectives. In addition, we conducted an email-based survey for collecting usage data and current status of contemporary AAL systems. We found that most AAL systems are confined to a limited set of features ignoring many of the essential AAL system aspects. Standards and technologies are used in a limited and isolated manner, while quality attributes are often addressed insufficiently. In conclusion, we found that more inter-organizational collaboration, user-centered studies, increased standardization efforts, and a focus on open systems is needed to achieve more interoperable and synergetic AAL solutions.

  10. A framework for multi-platform mobile mapping data registration

    Science.gov (United States)

    Hassan, Taher Fathy

    Currently, there is an enormous number of Geomatics sensory data available for use in mapping applications. These data are collected from different platforms, using different sensors, and encapsulating different amount of information. The topic of multi-sensor data fusion has received, over the years, a lot of attention by the scientific community for many applications. Multi-sensor data fusion techniques combine data from multiple sensors and related information from associated databases, to achieve improved accuracies and more specific inferences than could be achieved by the use of a single sensor alone. Mobile mapping systems are efficient tools for collecting multi-sensor data that can be used to build and update geographic information systems base maps. The concept of mobile mapping became the mapping standard. Despite the first mobile mapping system was installed on a van, the application has no longer limited to vans. It is now installed on various types of platforms, running in land, sea, and air. Many researchers have proposed different fusion schemes for integrating different sensory data. This fusion process can be broadly classified into pictorial to pictorial, pictorial to non-pictorial, and non pictorial to non-pictorial. Yet, many researchers have investigated different fusion schemes, however there is less amount of attention towards the fusion of airborne and land-based mobile mapping systems' imagery/navigation data. This research introduces a novel data fusion scheme between mobile mapping data, collected from different platforms. The fusion includes both pictorial measurements, in addition to navigation data available from system's navigation component. The fusion is done using generic Bundle Adjustment (BA) engine, which is a generalization of the standard bundle adjustment frameworks. The proposed framework has been adapted to fit the special requirements imposed by the proposed fusion scheme like higher order registration primitives, multi

  11. Extending XNAT Platform with an Incremental Semantic Framework

    Directory of Open Access Journals (Sweden)

    Santiago Timón

    2017-08-01

    Full Text Available Informatics increases the yield from neuroscience due to improved data. Data sharing and accessibility enable joint efforts between different research groups, as well as replication studies, pivotal for progress in the field. Research data archiving solutions are evolving rapidly to address these necessities, however, distributed data integration is still difficult because of the need of explicit agreements for disparate data models. To address these problems, ontologies are widely used in biomedical research to obtain common vocabularies and logical descriptions, but its application may suffer from scalability issues, domain bias, and loss of low-level data access. With the aim of improving the application of semantic models in biobanking systems, an incremental semantic framework that takes advantage of the latest advances in biomedical ontologies and the XNAT platform is designed and implemented. We follow a layered architecture that allows the alignment of multi-domain biomedical ontologies to manage data at different levels of abstraction. To illustrate this approach, the development is integrated in the JPND (EU Joint Program for Neurodegenerative Disease APGeM project, focused on finding early biomarkers for Alzheimer's and other dementia related diseases.

  12. Research on Framework of Digital Process Planning Platform

    Institute of Scientific and Technical Information of China (English)

    MA Yumin; FAN Liuqun; ZHU Zhihao; ZHANG Hao

    2006-01-01

    Digital factory technology is a research focus in academe and industry, which is an advanced manufacturing technology that is proposed to bridge product development and manufacturing. For applying digital factory technology in machining domain, a concept of digital process planning and its framework are suggested, its components including machining domain knowledge model, machining knowledge base, machining resource base and process planning system are studied. The framework of digital process planning is of value for implementing digital factory technology in machining industry.

  13. Digital platforms: an analytical framework for identifying and evaluating policy options

    NARCIS (Netherlands)

    van Eijk, N.; Fahy, R.; van Til, H.; Nooren, P.; Stokking, H.; Gelevert, H.

    2015-01-01

    At the request of the Ministry of Economic Affairs, a project consortium of TNO, Ecorys and IViR have developed a framework to analyse policy questions regarding ‘digital platforms’. This framework enables the government to take advantage of the opportunities these platforms offer and to appreciate

  14. Digital platforms: an analytical framework for identifying and evaluating policy options

    NARCIS (Netherlands)

    van Eijk, N.; Fahy, R.; van Til, H.; Nooren, P.; Stokking, H.; Gelevert, H.

    2015-01-01

    At the request of the Ministry of Economic Affairs, a project consortium of TNO, Ecorys and IViR have developed a framework to analyse policy questions regarding ‘digital platforms’. This framework enables the government to take advantage of the opportunities these platforms offer and to appreciate

  15. Towards A Framework of Digital Payment Platform Design

    DEFF Research Database (Denmark)

    Kazan, Erol; Damsgaard, Jan

    This paper focuses on the triumph march of mobile phones that currently are annexing music players, navigation devices, and cameras as separate physical objects. The next target is set on payment. Through synthesizing available literature, we construct a framework for studying digital payment pla...

  16. Metal-Organic Frameworks as Platforms for Functional Materials.

    Science.gov (United States)

    Cui, Yuanjing; Li, Bin; He, Huajun; Zhou, Wei; Chen, Banglin; Qian, Guodong

    2016-03-15

    Discoveries of novel functional materials have played very important roles to the development of science and technologies and thus to benefit our daily life. Among the diverse materials, metal-organic framework (MOF) materials are rapidly emerging as a unique type of porous and organic/inorganic hybrid materials which can be simply self-assembled from their corresponding inorganic metal ions/clusters with organic linkers, and can be straightforwardly characterized by various analytical methods. In terms of porosity, they are superior to other well-known porous materials such as zeolites and carbon materials; exhibiting extremely high porosity with surface area up to 7000 m(2)/g, tunable pore sizes, and metrics through the interplay of both organic and inorganic components with the pore sizes ranging from 3 to 100 Å, and lowest framework density down to 0.13 g/cm(3). Such unique features have enabled metal-organic frameworks to exhibit great potentials for a broad range of applications in gas storage, gas separations, enantioselective separations, heterogeneous catalysis, chemical sensing and drug delivery. On the other hand, metal-organic frameworks can be also considered as organic/inorganic self-assembled hybrid materials, we can take advantages of the physical and chemical properties of both organic and inorganic components to develop their functional optical, photonic, and magnetic materials. Furthermore, the pores within MOFs can also be utilized to encapsulate a large number of different species of diverse functions, so a variety of functional MOF/composite materials can be readily synthesized. In this Account, we describe our recent research progress on pore and function engineering to develop functional MOF materials. We have been able to tune and optimize pore spaces, immobilize specific functional groups, and introduce chiral pore environments to target MOF materials for methane storage, light hydrocarbon separations, enantioselective recognitions

  17. A Contextualised Multi-Platform Framework to Support Blended Learning Scenarios in Learning Networks

    NARCIS (Netherlands)

    De Jong, Tim; Fuertes, Alba; Schmeits, Tally; Specht, Marcus; Koper, Rob

    2008-01-01

    De Jong, T., Fuertes, A., Schmeits, T., Specht, M., & Koper, R. (2009). A Contextualised Multi-Platform Framework to Support Blended Learning Scenarios in Learning Networks. In D. Goh (Ed.), Multiplatform E-Learning Systems and Technologies: Mobile Devices for Ubiquitous ICT-Based Education (pp. 1-1

  18. A Contextualised Multi-Platform Framework to Support Blended Learning Scenarios in Learning Networks

    NARCIS (Netherlands)

    De Jong, Tim; Fuertes, Alba; Schmeits, Tally; Specht, Marcus; Koper, Rob

    2008-01-01

    De Jong, T., Fuertes, A., Schmeits, T., Specht, M., & Koper, R. (2009). A Contextualised Multi-Platform Framework to Support Blended Learning Scenarios in Learning Networks. In D. Goh (Ed.), Multiplatform E-Learning Systems and Technologies: Mobile Devices for Ubiquitous ICT-Based Education (pp.

  19. [Methods of development of recommendations for clinical practice (RCP) and of setting-up of a platform cancer heart vessels (PTF-CHV) in the inter3C Vaucluse-Arles].

    Science.gov (United States)

    Debourdeau, Philippe; Meuleman, Catherine; Dufaitre, Ghislaine; Laroche, Jean-Pierre; Slama, Borhane; Chebrek, Safia; Aboukhoudir, Falah; Mège, Alice; Dotigny, Robert; Serin, Daniel

    2015-11-01

    Monitoring and prevention of cardiovascular complications of anti-neoplastic treatment are currently well known for anthracyclines and trastuzumab but remain poorly implemented. The management of cardiac and vascular side effects of targeted therapies is not codified. The purpose of the platform heart-vessel cancer is to optimize the management of such complications within a small area (Vaucluse region of Arles). The platform will offer prescribers an easily accessible database, doctors performing exams standardized monitoring forms and patients a uniform follow-up. We report here the methodology of the elaboration of recommendations for clinical practice and the ways to develop the platform. After a year of active process, an analysis of the will be performed to see opportunities for improvement and dissemination on a larger scale. Copyright © 2015 Société Française du Cancer. Published by Elsevier Masson SAS. All rights reserved.

  20. Mobile Context Toolbox - An Extensible Context Framework for the Maemo Platform

    DEFF Research Database (Denmark)

    Stopczynski, Arkadiusz; Larsen, Jakob Eg; Skomial, Lukasz

    2011-01-01

    to the context framework. We present initial results from in-the-wild experiments where contextual data was acquired using the tool. In the experiments 6 participants were using a Nokia N900 mobile phone continuously with a logger application for an average of 33 days. The study has provided valuable insights......In this paper we describe an open framework utilizing sensors and application data on the Maemo mobile platform enabling rapid prototyping of context-aware mobile applications. The framework has an extensible layered architecture allowing new hardware and software sensors and features to be added...... into human behavior in terms of places visited, people met, etc. Moreover, it has provided useful insights into platform issues of the system deployed in real-life usage situations, including the stability and power consumption....

  1. Framework Programmable Platform for the Advanced Software Development Workstation: Preliminary system design document

    Science.gov (United States)

    Mayer, Richard J.; Blinn, Thomas M.; Mayer, Paula S. D.; Ackley, Keith A.; Crump, John W., IV; Henderson, Richard; Futrell, Michael T.

    1991-01-01

    The Framework Programmable Software Development Platform (FPP) is a project aimed at combining effective tool and data integration mechanisms with a model of the software development process in an intelligent integrated software environment. Guided by the model, this system development framework will take advantage of an integrated operating environment to automate effectively the management of the software development process so that costly mistakes during the development phase can be eliminated. The focus here is on the design of components that make up the FPP. These components serve as supporting systems for the Integration Mechanism and the Framework Processor and provide the 'glue' that ties the FPP together. Also discussed are the components that allow the platform to operate in a distributed, heterogeneous environment and to manage the development and evolution of software system artifacts.

  2. A Universal Communication Framework and Navigation Control Software for Mobile Prototyping Platforms

    Directory of Open Access Journals (Sweden)

    Andreas Mitschele-Thiel

    2010-09-01

    Full Text Available In our contribution we would like to describe two new aspects of our low-cost mobile prototyping platform concept: a new hardware communication framework as well as new software features for navigation and control of our mobile platform. The paper is an extension of the ideas proposed in REV2009 [1] and is based on the therein used hardware platform and the monitoring and management software. This platform is based on the Quadrocopter concept – autonomous flying helicopter-style robots – and includes additional off-the-shelf parts. This leads to a universal mobile prototyping platform for communication tasks providing both mobile phone and WiFi access. However, the platform can provide these functions far more quickly than a technician on the ground might be able to. We will show that with our concept we can easily adapt the platform to the individual needs of the user, which leads to a very flexible and semi-autonomous system.

  3. A Framework for Analyzing Digital Payment as a Multi-sided Platform

    DEFF Research Database (Denmark)

    Kazan, Erol; Damsgaard, Jan

    2013-01-01

    Near Field Communication (NFC) is a promising digital payment technology that is expected to substitute cash. However, despite its potential, NFC-based payment has not reached mass adoption on the customer nor on the merchant side. This paper constructs a preliminary framework for studying digital...... payment instruments to their existing customer base. In addition, they extend their existing platform with other contactless services, thereby transforming existing cards (SIM or debit) from single-purpose to multi-functional cards. Our research extends existing payment literature from the MSP perspective...... to accommodate technological developments, where technology (NFC) and platform design impact market actor strategies and complementary products....

  4. Histostitcher™: An informatics software platform for reconstructing whole-mount prostate histology using the extensible imaging platform framework

    Directory of Open Access Journals (Sweden)

    Robert J Toth

    2014-01-01

    Full Text Available Context: Co-registration of ex-vivo histologic images with pre-operative imaging (e.g., magnetic resonance imaging [MRI] can be used to align and map disease extent, and to identify quantitative imaging signatures. However, ex-vivo histology images are frequently sectioned into quarters prior to imaging. Aims: This work presents Histostitcher™, a software system designed to create a pseudo whole mount histology section (WMHS from a stitching of four individual histology quadrant images. Materials and Methods: Histostitcher™ uses user-identified fiducials on the boundary of two quadrants to stitch such quadrants. An original prototype of Histostitcher™ was designed using the Matlab programming languages. However, clinical use was limited due to slow performance, computer memory constraints and an inefficient workflow. The latest version was created using the extensible imaging platform (XIP™ architecture in the C++ programming language. A fast, graphics processor unit renderer was designed to intelligently cache the visible parts of the histology quadrants and the workflow was significantly improved to allow modifying existing fiducials, fast transformations of the quadrants and saving/loading sessions. Results: The new stitching platform yielded significantly more efficient workflow and reconstruction than the previous prototype. It was tested on a traditional desktop computer, a Windows 8 Surface Pro table device and a 27 inch multi-touch display, with little performance difference between the different devices. Conclusions: Histostitcher™ is a fast, efficient framework for reconstructing pseudo WMHS from individually imaged quadrants. The highly modular XIP™ framework was used to develop an intuitive interface and future work will entail mapping the disease extent from the pseudo WMHS onto pre-operative MRI.

  5. MATRIX-AGENT FRAMEWORK:A VIRTUAL PLATFORM FOR MULTI-AGENTS

    Institute of Scientific and Technical Information of China (English)

    Hao Lan ZHANG; Clement H.C. LEUNG; Gitesh K. RAIKUNDALIA

    2006-01-01

    Multi-agent technology has been applied extensively to many areas, including Decision Support Systems (DSS). However, the applications of multi-agent technology in DSS are still very preliminary.Most of the current agent frameworks, such as middle-agent-based or agent-facilitator-based frameworks, are basically agent-to-agent model. These agent-based frameworks often neglect the living environment for agents and they suffer from: (i) inability to adapt to the environment, (ii)inability to self-upgrade, and (iii) inefficiency in information acquisition. Here, we introduce a recently proposed multi-agent framework, namely Agent-based Open Connectivity for Decision Support Systems (AOCD). In this new framework, the communication and cooperation between agents are through a key component, the Matrix, which provides a virtual platform for agents. We use a unified Matrices framework to solve the bottleneck problem in the AOCD framework. Our experimental results based on different agent network topologies indicate that the hybrid topology presents superior performance compared with the centralised and decentralised topologies.

  6. Organisational support for the EU platform level action to support innovative efforts for a new scholarly communication framework

    OpenAIRE

    Dekeyser, Raf

    2001-01-01

    Conclusions of the report of the panel discussion about the future of the scholarly communication "Organisational support for the EU platform level action to support innovative efforts for a new scholarly communication framework"

  7. RCP 劲性复合桩的应用%The application of RCP composite pile

    Institute of Scientific and Technical Information of China (English)

    宋阳

    2016-01-01

    介绍了 RCP 劲性复合桩的技术原理,结合工程案例,从定点放线、搅拌钻进、水泥浆制作、桩芯植入等方面,阐述了 RCP 劲性复合桩的施工工艺流程及要点,并介绍了该技术的优点,可为其他项目桩基工程提供参考。%This paper introduced the technology principle of RCP composite piles,combining with the engineering case,starting from aspects of fixed-point sampling,mixing drilling,cement slurry prefabrication and inside pile planting,describes the construction process and points of RCP composite pile,and introduces the advantages of the technology,can provide a reference for other projects pile works.

  8. A SOA-Based Platform-Specific Framework for Context-Aware Mobile Applications

    Science.gov (United States)

    Daniele, Laura M.; Silva, Eduardo; Pires, Luís Ferreira; van Sinderen, Marten

    Context-aware mobile applications are intelligent applications that can monitor the user’s context and, in case of changes in this context, consequently adapt their behaviour in order to satisfy the user’s current needs or anticipate the user’s intentions. The design of such applications relies on dynamic middleware platforms that consist of a variety of components. These components are distributed in the environment and interoperate by making use of each other’s services. In the A-MUSE project, we defined a design methodology based on MDA principles that relies on a SOA reference architecture for context-aware mobile applications. This paper shows how abstract concepts in the design of such applications can be applied to realize concrete components that guarantee architectural interoperability. We also present a platform-specific framework that uses BPEL, UDDI registry and web services as target technologies to implement our reference architecture.

  9. Biochemical characterization of riboflavin carrier protein (RCP) in prostate cancer.

    Science.gov (United States)

    Johnson, Tanya; Ouhtit, Allal; Gaur, Rajiv; Fernando, Augusta; Schwarzenberger, Paul; Su, Joseph; Ismail, Mohamed F; El-Sayyad, Hassan I; Karande, Anjali; Elmageed, Zakaria Abd; Rao, Prakash; Raj, Madhwa

    2009-01-01

    Riboflavin carrier protein (RCP) is a growth- and development-specific protein. Here, we characterized the expression of this protein in prostate cancer by polyclonal and monoclonal antibodies against chicken RCP. RCP was localized to both androgen-dependent and independent prostate cancer cell lines. Compared to controls, RCP was over-expressed in all 45 prostate adenocarcinomas, irrespective of the Gleason's score or the stage of the disease. The identified RCP had a molecular weight of 38 kDa, similar to RCP purified from chicken. Presence of this protein was also confirmed by siRNA inhibition analysis. Antibodies to chicken RCP inhibited incorporation of tritiated thymidine into DNA and prevented riboflavin uptake in PC3 prostate cancer cells, suggesting a critical function of this protein in prostate cancer cell growth. These data suggest that RCP can be used as a tumor biomarker in prostate cancer.

  10. Framework of Digital Machining Process Planning Platform for Cylinder Body Part

    Institute of Scientific and Technical Information of China (English)

    MA Yu-min; FAN Liu-qun; ZHU Zhi-hao; ZHANG Hao

    2007-01-01

    Digital factory technology is an advanced manufacturing technology served as to establish a bridge between the process of product development and manufacturing. In terms of application for digital factory technology in machining, especially in machining of a complicated part such as a cylinder body part, a concept of digital process planning and its framework are proposed. Its components including machining domain knowledge model, machining knowledge base, machining resource base and process planning system are studied. A machining knowledge model in tree form and an object-driven knowledge reasoning mechanism are used for machining knowledge base. The process planning system is a user interface that leads a planner to finish the planning process. A case about a cylinder head part is given to demonstrate how the platform works. The framework of digital process planning is the foundation of some intelligent CAPP systems and helps to production line planning.

  11. Platform-level Distributed Warfare Model-based on Multi-Agent System Framework

    Directory of Open Access Journals (Sweden)

    Xiong Li

    2012-05-01

    Full Text Available The multi-agent paradigm has become a useful tool in solving military problems. However, one of key challenges in multi-agent model for distributed warfare could be how to describe the microcosmic  tactical warfare platforms actions. In this paper, a platform-level distributed warfare model based on multi-agent system framework is designed to tackle this challenge. The basic ideas include:  Establishing multi-agent model by mapping from tactical warfare system’s members, i.e., warfare platforms, to respective agents; performing task decomposition and task allocation by using task-tree decomposition method and improved contract net protocol model technique; and implementing simulation by presenting battlefield terrain environment analysis algorithm based on grid approach. The  simulation demonstration results show that our model provides a feasible and effective approach to supporting the abstraction and representation of microcosmic tactical actions for complex warfare system.Defence Science Journal, 2012, 62(1, pp.180-186, DOI:http://dx.doi.org/10.14429/dsj.62.964

  12. US NDC Modernization Iteration E2 Prototyping Report: User Interface Framework

    Energy Technology Data Exchange (ETDEWEB)

    Lewis, Jennifer E. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Palmer, Melanie A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Vickers, James Wallace [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Voegtli, Ellen M. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2014-12-01

    During the second iteration of the US NDC Modernization Elaboration phase (E2), the SNL US NDC Modernization project team completed follow-on Rich Client Platform (RCP) exploratory prototyping related to the User Interface Framework (UIF). The team also developed a survey of browser-based User Interface solutions and completed exploratory prototyping for selected solutions. This report presents the results of the browser-based UI survey, summarizes the E2 browser-based UI and RCP prototyping work, and outlines a path forward for the third iteration of the Elaboration phase (E3).

  13. An Open Data Platform in the framework of the EGI-LifeWatch Competence Center

    Science.gov (United States)

    Aguilar Gómez, Fernando; de Lucas, Jesús Marco; Yaiza Rodríguez Marrero, Ana

    2016-04-01

    The working pilot of an Open Data Platform supporting the full data cycle in research is presented. It aims to preserve knowledge explicitly, starting with the description of the Case Studies, and integrating data and software management and preservation on equal basis. The uninterrupted support in the chain starts at the data acquisition level and covers up to the support for reuse and publication in an open framework, providing integrity and provenance controls. The Lifewatch Open Science Framework is a pilot web portal developed in collaboration with different commercial companies that tries to enrich and integrate different data lifecycle-related tools in order to address the management of the different steps: data planning, gathering, storing, curation, preservation, sharing, discovering, etc. To achieve this goal, the platform includes the following features: -Data Management Planning. Tool to set up an structure of the data, including what data will be generated, how it will be exploited, re-used, curated, preserved, etc. It has a semantic approach: includes reference to ontologies in order to express what data will be gathered. -Close to instrumentation. The portal includes a distributed storage system that can be used both for storing data from instruments and output data from analysis. All that data can be shared -Analysis. Resources from EGI Federated Cloud are accessible within the portal, so that users can exploit computing resources to perform analysis and other processes, including workflows. -Preservation. Data can be preserved in different systems and DOIs can be minted not only for datasets but also for software, DMPs, etc. The presentation will show the different components of the framework as well as how it can be extrapolated to other communities.

  14. Covalent organic frameworks: a materials platform for structural and functional designs

    Science.gov (United States)

    Huang, Ning; Wang, Ping; Jiang, Donglin

    2016-10-01

    Covalent organic frameworks (COFs) are a class of crystalline porous polymer that allows the atomically precise integration of organic units into extended structures with periodic skeletons and ordered nanopores. One important feature of COFs is that they are designable; that is, the geometry and dimensions of the building blocks can be controlled to direct the topological evolution of structural periodicity. The diversity of building blocks and covalent linkage topology schemes make COFs an emerging materials platform for structural control and functional design. Indeed, COF architectures offer confined molecular spaces for the interplay of photons, excitons, electrons, holes, ions and guest molecules, thereby exhibiting unique properties and functions. In this Review, we summarize the major progress in the field of COFs and recent achievements in developing new design principles and synthetic strategies. We highlight cutting-edge functional designs and identify fundamental issues that need to be addressed in conjunction with future research directions from chemistry, physics and materials perspectives.

  15. Lilith: A Java framework for the development of scalable tools for high performance distributed computing platforms

    Energy Technology Data Exchange (ETDEWEB)

    Evensky, D.A.; Gentile, A.C.; Armstrong, R.C.

    1998-03-19

    Increasingly, high performance computing constitutes the use of very large heterogeneous clusters of machines. The use and maintenance of such clusters are subject to complexities of communication between the machines in a time efficient and secure manner. Lilith is a general purpose tool that provides a highly scalable, secure, and easy distribution of user code across a heterogeneous computing platform. By handling the details of code distribution and communication, such a framework allows for the rapid development of tools for the use and management of large distributed systems. Lilith is written in Java, taking advantage of Java`s unique features of loading and distributing code dynamically, its platform independence, its thread support, and its provision of graphical components to facilitate easy to use resultant tools. The authors describe the use of Lilith in a tool developed for the maintenance of the large distributed cluster at their institution and present details of the Lilith architecture and user API for the general user development of scalable tools.

  16. Predicting the responses of forest distribution and aboveground biomass to climate change under RCP scenarios in southern China.

    Science.gov (United States)

    Dai, Erfu; Wu, Zhuo; Ge, Quansheng; Xi, Weimin; Wang, Xiaofan

    2016-11-01

    In the past three decades, our global climate has been experiencing unprecedented warming. This warming has and will continue to significantly influence the structure and function of forest ecosystems. While studies have been conducted to explore the possible responses of forest landscapes to future climate change, the representative concentration pathways (RCPs) scenarios under the framework of the Coupled Model Intercomparison Project Phase 5 (CMIP5) have not been widely used in quantitative modeling research of forest landscapes. We used LANDIS-II, a forest dynamic landscape model, coupled with a forest ecosystem process model (PnET-II), to simulate spatial interactions and ecological succession processes under RCP scenarios, RCP2.6, RCP4.5 and RCP8.5, respectively. We also modeled a control scenario of extrapolating current climate conditions to examine changes in distribution and aboveground biomass (AGB) among five different forest types for the period of 2010-2100 in Taihe County in southern China, where subtropical coniferous plantations dominate. The results of the simulation show that climate change will significantly influence forest distribution and AGB. (i) Evergreen broad-leaved forests will expand into Chinese fir and Chinese weeping cypress forests. The area percentages of evergreen broad-leaved forests under RCP2.6, RCP4.5, RCP8.5 and the control scenarios account for 18.25%, 18.71%, 18.85% and 17.46% of total forest area, respectively. (ii) The total AGB under RCP4.5 will reach its highest level by the year 2100. Compared with the control scenarios, the total AGB under RCP2.6, RCP4.5 and RCP8.5 increases by 24.1%, 64.2% and 29.8%, respectively. (iii) The forest total AGB increases rapidly at first and then decreases slowly on the temporal dimension. (iv) Even though the fluctuation patterns of total AGB will remain consistent under various future climatic scenarios, there will be certain responsive differences among various forest types. © 2016

  17. The concept of rural community practice (RCP).

    Science.gov (United States)

    Nielsen, N Ole; Evans, Brian; King, Lonnie J

    2006-01-01

    The need to devote more human resources to veterinary public practice to cope with escalating threats to biological security, public health, and economic prosperity, while also addressing societal value changes, has been widely recognized and supported. Most envisage increasing the numbers of veterinarians in government employment. Why not at least combine this initiative, wherever possible, with far greater involvement of rural practitioners to deliver contractual public-practice services and provide an enhanced community interface? This could make the difference between having a local practice in a community or none at all, as well as promising to be more cost effective. The concept of rural community practice (RCP) envisages combining traditional services provided in a "mixed-animal" veterinary practice with an expanded portfolio of public-practice and communication services that meet the emerging animal, public, and ecosystem health needs of the collective community, not just those of animal owners. These services could include those involving active sentinel surveillance programs for both domestic animal and wildlife diseases; on-farm food safety; bio-security; traceability and export certification and audit programs; disease investigation, including foreign animal diseases; surge capacity emergency response; managing for ecosystem health; and client and community education. An expanded practice team of animal-health professionals and technologists, led by veterinarians, would deliver these services. This RCP approach should have the potential to make rural practice more attractive from economic, lifestyle, and job-satisfaction perspectives; to enhance the visibility and recognition of the profession; and to respond to changing and new societal needs. It also promises to maintain a stable network of veterinary practices in rural communities. In addition, the recognition of veterinary medicine as a public good should provide for consideration of increased

  18. Developing a Conceptual Framework for Simulation Analysis in a Supply Chain Based on Common Platform (SCBCP

    Directory of Open Access Journals (Sweden)

    M. Fathollah

    2009-08-01

    Full Text Available As a competitive advantage in modern organizations, product diversification may cause complexities in today’s extended supplychains. However, the Common Platform (CP Strategy, as a concept of gaining maximum variety by minimum productionelements, is believed to be one of the answers to eliminate or decrease these complexities. The main purpose of this paper is toprovide a simulation framework for modeling the supply network of a case study in automotive industry in order to study theimpacts of part commonality through the chain. The electrical wiring harness is selected as the main part to be studiedaccording to essentiality and challenges of its procurement for the production of cars (as occurred in this case and many otherstudies. The paper does not provide the simulation results but it rather builds up the required foundation and gathers therelevant content to develop a realistic simulation model by closely studying the impacts of part multiplicity on differentfunctional areas of the selected supply network and extracting the critical success factors of applying part commonality.

  19. Android Platform Based Smartphones for a Logistical Remote Association Repair Framework

    Directory of Open Access Journals (Sweden)

    Shao-Fan Lien

    2014-06-01

    Full Text Available The maintenance of large-scale systems is an important issue for logistics support planning. In this paper, we developed a Logistical Remote Association Repair Framework (LRARF to aid repairmen in keeping the system available. LRARF includes four subsystems: smart mobile phones, a Database Management System (DBMS, a Maintenance Support Center (MSC and wireless networks. The repairman uses smart mobile phones to capture QR-codes and the images of faulty circuit boards. The captured QR-codes and images are transmitted to the DBMS so the invalid modules can be recognized via the proposed algorithm. In this paper, the Linear Projective Transform (LPT is employed for fast QR-code calibration. Moreover, the ANFIS-based data mining system is used for module identification and searching automatically for the maintenance manual corresponding to the invalid modules. The inputs of the ANFIS-based data mining system are the QR-codes and image features; the output is the module ID. DBMS also transmits the maintenance manual back to the maintenance staff. If modules are not recognizable, the repairmen and center engineers can obtain the relevant information about the invalid modules through live video. The experimental results validate the applicability of the Android-based platform in the recognition of invalid modules. In addition, the live video can also be recorded synchronously on the MSC for later use.

  20. Android Platform Based Smartphones for a Logistical Remote Association Repair Framework

    Science.gov (United States)

    Lien, Shao-Fan; Wang, Chun-Chieh; Su, Juhng-Perng; Chen, Hong-Ming; Wu, Chein-Hsing

    2014-01-01

    The maintenance of large-scale systems is an important issue for logistics support planning. In this paper, we developed a Logistical Remote Association Repair Framework (LRARF) to aid repairmen in keeping the system available. LRARF includes four subsystems: smart mobile phones, a Database Management System (DBMS), a Maintenance Support Center (MSC) and wireless networks. The repairman uses smart mobile phones to capture QR-codes and the images of faulty circuit boards. The captured QR-codes and images are transmitted to the DBMS so the invalid modules can be recognized via the proposed algorithm. In this paper, the Linear Projective Transform (LPT) is employed for fast QR-code calibration. Moreover, the ANFIS-based data mining system is used for module identification and searching automatically for the maintenance manual corresponding to the invalid modules. The inputs of the ANFIS-based data mining system are the QR-codes and image features; the output is the module ID. DBMS also transmits the maintenance manual back to the maintenance staff. If modules are not recognizable, the repairmen and center engineers can obtain the relevant information about the invalid modules through live video. The experimental results validate the applicability of the Android-based platform in the recognition of invalid modules. In addition, the live video can also be recorded synchronously on the MSC for later use. PMID:24967603

  1. Multifunctional, Tunable Metal-Organic Framework Materials Platform for Bioimaging Applications.

    Science.gov (United States)

    Sava Gallis, Dorina F; Rohwer, Lauren E S; Rodriguez, Mark A; Barnhart-Dailey, Meghan C; Butler, Kimberly S; Luk, Ting S; Timlin, Jerilyn A; Chapman, Karena W

    2017-07-12

    Herein, we describe a novel multifunctional metal-organic framework (MOF) materials platform that displays both porosity and tunable emission properties as a function of the metal identity (Eu, Nd, and tuned compositions of Nd/Yb). Their emission collectively spans the deep red to near-infrared (NIR) spectral region (∼614-1350 nm), which is highly relevant for in vivo bioimaging. These new materials meet important prerequisites as relevant to biological processes: they are minimally toxic to living cells and retain structural integrity in water and phosphate-buffered saline. To assess their viability as optical bioimaging agents, we successfully synthesized the nanoscale Eu analog as a proof-of-concept system in this series. In vitro studies show that it is cell-permeable in individual RAW 264.7 mouse macrophage and HeLa human cervical cancer tissue culture cells. The efficient discrimination between the Eu emission and cell autofluorescence was achieved with hyperspectral confocal fluorescence microscopy, used here for the first time to characterize MOF materials. Importantly, this is the first report that documents the long-term conservation of the intrinsic emission in live cells of a fluorophore-based MOF to date (up to 48 h). This finding, in conjunction with the materials' very low toxicity, validates the biocompatibility in these systems and qualifies them as promising for use in long-term tracking and biodistribution studies.

  2. PaRSEC: A Software Framework for Performance and Productivity on Hybrid, Manycore Platforms

    Energy Technology Data Exchange (ETDEWEB)

    Dongarra, Jack [Univ. of Tennessee, Knoxville, TN (United States)

    2016-06-30

    As the era of computer architectures dominated by serial processors ends, the convergence of several unprecedented challenges suggests that closing the longstanding "application–architecture performance gap" will become more challenging than ever. To address this problem, the Parallel Runtime Scheduling and Execution Control (PaRSEC) project created a modular software framework that achieved two major objectives: first, it built a task-based runtime capable of delivering portable performance to a wide range of science and engineering applications at all levels of the platform pyramid, including the upcoming 100 Pflop/s systems and then exascale; and second, it supported and facilitated the work of developers in migrating their legacy codes and writing entirely new ones for the emerging hybrid and massively parallel manycore processor system designs. PaRSEC will support multiple domain-specific languages capable of increasing the developers' productivity while also providing the runtime with the constructs and flexibility necessary to exploit the maximal parallelism from parallel applications. Extensive preliminary research in dense linear algebra showed convincingly that a parameterized task graph representation that symbolically describes the algorithm content can achieve the project's twofold objective within that domain. The research also strongly suggested that this powerful method could be generalized to a far-wider variety of applications.

  3. Framework Programmable Platform for the Advanced Software Development Workstation (FPP/ASDW). Demonstration framework document. Volume 1: Concepts and activity descriptions

    Science.gov (United States)

    Mayer, Richard J.; Blinn, Thomas M.; Dewitte, Paul S.; Crump, John W.; Ackley, Keith A.

    1992-01-01

    The Framework Programmable Software Development Platform (FPP) is a project aimed at effectively combining tool and data integration mechanisms with a model of the software development process to provide an intelligent integrated software development environment. Guided by the model, this system development framework will take advantage of an integrated operating environment to automate effectively the management of the software development process so that costly mistakes during the development phase can be eliminated. The Advanced Software Development Workstation (ASDW) program is conducting research into development of advanced technologies for Computer Aided Software Engineering (CASE).

  4. Instant Eclipse 4 RCP development how-to

    CERN Document Server

    Kulkarni, Ram

    2013-01-01

    Filled with practical, step-by-step instructions and clear explanations for the most important and useful tasks.A concise guide that delivers immediate results with practical recipes on learning practical hints and avoiding pitfalls in Eclipse 4 development.You will find this book useful if you are looking to create cross-platform rich client applications. Eclipse platform is built with Java, so basic knowledge of Java is essential. The focus of this book is to understand the new APIs and concepts of the Eclipse 4 platform. Prior knowledge of basic concepts of the Eclipse framework (plugin, ex

  5. Ocean Data Interoperability Platform: developing a common global framework for marine data management

    Science.gov (United States)

    Glaves, Helen; Schaap, Dick

    2017-04-01

    elsewhere. To add a further layer of complexity there are also global initiatives providing marine data infrastructures e.g. IOC-IODE, POGO as well as those with a wider remit which includes environmental data e.g. GEOSS, COPERNICUS etc. Ecosystem level marine research requires a common framework for marine data management that supports the sharing of data across these regional and global data systems, and provides the user with access to the data available from these services via a single point of access. This framework must be based on existing data systems and established by developing interoperability between them. The Ocean Data and Interoperability Platform (ODIP/ODIP II) project brings together those organisations responsible for maintaining selected regional data infrastructures along with other relevant experts in order to identify the common standards and best practice necessary to underpin this framework, and to evaluate the differences and commonalties between the regional data infrastructures in order to establish interoperability between them for the purposes of data sharing. This coordinated approach is being demonstrated and validated through the development of a series of prototype interoperability solutions that demonstrate the mechanisms and standards necessary to facilitate the sharing of marine data across these existing data infrastructures.

  6. Creating a Discovery Platform for Confined-Space Chemistry and Materials: Metal-Organic Frameworks.

    Energy Technology Data Exchange (ETDEWEB)

    Allendorf, Mark D.; Greathouse, Jeffery A.; Simmons, Blake

    2008-09-01

    Metal organic frameworks (MOF) are a recently discovered class of nanoporous, defect-free crystalline materials that enable rational design and exploration of porous materials at the molecular level. MOFs have tunable monolithic pore sizes and cavity environments due to their crystalline nature, yielding properties exceeding those of most other porous materials. These include: the lowest known density (91% free space); highest surface area; tunable photoluminescence; selective molecular adsorption; and methane sorption rivaling gas cylinders. These properties are achieved by coupling inorganic metal complexes such as ZnO4 with tunable organic ligands that serve as struts, allowing facile manipulation of pore size and surface area through reactant selection. MOFs thus provide a discovery platform for generating both new understanding of chemistry in confined spaces and novel sensors and devices based on their unique properties. At the outset of this project in FY06, virtually nothing was known about how to couple MOFs to substrates and the science of MOF properties and how to tune them was in its infancy. An integrated approach was needed to establish the required knowledge base for nanoscale design and develop methodologies integrate MOFs with other materials. This report summarizes the key accomplishments of this project, which include creation of a new class of radiation detection materials based on MOFs, luminescent MOFs for chemical detection, use of MOFs as templates to create nanoparticles of hydrogen storage materials, MOF coatings for stress-based chemical detection using microcantilevers, and "flexible" force fields that account for structural changes in MOFs that occur upon molecular adsorption/desorption. Eight journal articles, twenty presentations at scientific conferences, and two patent applications resulted from the work. The project created a basis for continuing development of MOFs for many Sandia applications and succeeded in securing $2.75 M in

  7. Fundamental framework toward optimal design of product platform for industrial three-axis linear-type robots

    Directory of Open Access Journals (Sweden)

    Kana Sawai

    2015-07-01

    Full Text Available This paper discusses an optimization-based approach for the design of a product platform for industrial three-axis linear-type robots, which are widely used for handling objects in manufacturing lines. Since the operational specifications of these robots, such as operation speed, working distance and orientation, weight and shape of loads, etc., will vary for different applications, robotic system vendors must provide various types of robots efficiently and effectively to meet a range of market needs. A promising step toward this goal is the concept of a product platform, in which several key elements are commonly used across a series of products, which can then be customized for individual requirements. However the design of a product platform is more complicated than that of each product, due to the need to optimize the design across many products. This paper proposes an optimization-based fundamental framework toward the design of a product platform for industrial three-axis linear-type robots; this framework allows the solution of a complicated design problem and builds an optimal design method of fundamental features of robot frames that are commonly used for a wide range of robots. In this formulation, some key performance metrics of the robot are estimated by a reduced-order model which is configured with beam theory. A multi-objective optimization problem is formulated to represent the trade-offs among key design parameters using a weighted-sum form for a single product. This formulation is integrated into a mini–max type optimization problem across a series of robots as an optimal design formulation for the product platform. Some case studies of optimal platform design for industrial three-axis linear-type robots are presented to demonstrate the applications of a genetic algorithm to such mathematical models.

  8. Design and Implementation of an Efficient Software Communications Architecture Core Framework for a Digital Signal Processors Platform

    Directory of Open Access Journals (Sweden)

    Wael A. Murtada

    2011-01-01

    Full Text Available Problem statement: The Software Communications Architecture (SCA was developed to improve software reuse and interoperability in Software Defined Radios (SDR. However, there have been performance concerns since its conception. Arguably, the majority of the problems and inefficiencies associated with the SCA can be attributed to the assumption of modular distributed platforms relying on General Purpose Processors (GPPs to perform all signal processing. Approach: Significant improvements in cost and power consumption can be obtained by utilizing specialized and more efficient platforms. Digital Signal Processors (DSPs present such a platform and have been widely used in the communications industry. Improvements in development tools and middleware technology opened the possibility of fully integrating DSPs into the SCA. This approach takes advantage of the exceptional power, cost and performance characteristics of DSPs, while still enjoying the flexibility and portability of the SCA. Results: This study presents the design and implementation of an SCA Core Framework (CF for a TI TMS320C6416 DSP. The framework is deployed on a C6416 Device Cycle Accurate Simulator and TI C6416 Development board. The SCA CF is implemented by leveraging OSSIE, an open-source implementation of the SCA, to support the DSP platform. OIS’s ORBExpress DSP and DSP/BIOS are used as the middleware and operating system, respectively. A sample waveform was developed to demonstrate the framework’s functionality. Benchmark results for the framework and sample applications are provided. Conclusion: Benchmark results show that, using OIS ORBExpress DSP ORB middleware has an impact for decreasing the Software Memory Footprint and increasing the System Performance compared with PrismTech's e*ORB middleware.

  9. Transaction-based building controls framework, Volume 2: Platform descriptive model and requirements

    Energy Technology Data Exchange (ETDEWEB)

    Akyol, Bora A. [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Haack, Jereme N. [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Carpenter, Brandon J. [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Katipamula, Srinivas [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Lutes, Robert G. [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Hernandez, George [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)

    2015-07-31

    Transaction-based Building Controls (TBC) offer a control systems platform that provides an agent execution environment that meets the growing requirements for security, resource utilization, and reliability. This report outlines the requirements for a platform to meet these needs and describes an illustrative/exemplary implementation.

  10. Metal-Organic Frameworks as Potential Platforms for Carbon Dioxide Capture and Chemical Transformation

    Science.gov (United States)

    Gao, Wenyang

    The anthropogenic carbon dioxide (CO2) emission into the atmosphere, mainly through the combustion of fossil fuels, has resulted in a balance disturbance of the carbon cycle. Overwhelming scientific evidence proves that the escalating level of atmospheric CO2 is deemed as the main culprit for global warming and climate change. It is thus imperative to develop viable CO2 capture and sequestration (CCS) technologies to reduce CO2 emissions, which is also essential to avoid the potential devastating effects in future. The drawbacks of energy-cost, corrosion and inefficiency for amine-based wet-scrubbing systems which are currently used in industry, have prompted the exploration of alternative approaches for CCS. Extensive efforts have been dedicated to the development of functional porous materials, such as activated carbons, zeolites, porous organic polymers, and metal-organic frameworks (MOFs) to capture CO2. However, these adsorbents are limited by either poor selectivity for CO2 separation from gas mixtures or low CO2 adsorption capacity. Therefore, it is still highly demanding to design next-generation adsorbent materials fulfilling the requirements of high CO2 selectivity and enough CO2 capacity, as well as high water/moisture stability under practical conditions. Metal-organic frameworks (MOFs) have been positioned at the forefront of this area as a promising type of candidate amongst various porous materials. This is triggered by the modularity and functionality of pore size, pore walls and inner surface of MOFs by use of crystal engineering approaches. In this work, several effective strategies, such as incorporating 1,2,3-triazole groups as moderate Lewis base centers into MOFs and employing flexible azamacrocycle-based ligands to build MOFs, demonstrate to be promising ways to enhance CO 2 uptake capacity and CO2 separation ability of porous MOFs. It is revealed through in-depth studies on counter-intuitive experimental observations that the local electric

  11. The RCP-Rab11 complex regulates endocytic protein sorting.

    Science.gov (United States)

    Peden, Andrew A; Schonteich, Eric; Chun, John; Junutula, Jagath R; Scheller, Richard H; Prekeris, Rytis

    2004-08-01

    Rab 11 GTPase is an important regulator of endocytic membrane traffic. Recently, we and others have identified a novel family of Rab11 binding proteins, known as Rab11-family interacting proteins (FIPs). One of the family members, Rab coupling protein (RCP), was identified as a protein binding to both Rab4 and Rab11 GTPases. RCP was therefore suggested to serve a dual function as Rab4 and Rab11 binding protein. In this study, we characterized the cellular functions of RCP and mapped its interactions with Rab4 and Rab11. Our data show that RCP interacts only weakly with Rab4 in vitro and does not play the role of coupling Rab11 and Rab4 in vivo. Furthermore, our data indicate that the RCP-Rab11 complex regulates the sorting of transferrin receptors from the degradative to the recycling pathway. We therefore propose that RCP functions primarily as a Rab11 binding protein that regulates protein sorting in tubular endosomes.

  12. Synthesis, properties and formation of (RCp)Co- and (RCp)Rh-stabilized[4.8]3cyclacene derivatives.

    Science.gov (United States)

    Kornmayer, Stefan C; Hellbach, Björn; Rominger, Frank; Gleiter, Rolf

    2009-01-01

    Metal-stabilized belts: A torus, 3, consisting of three four- and three eight-membered conjugated rings and stabilized by (RCp)Co- and (RCp)Rh- units, was generated by irradiation of [(RCp)Co(CO)(2)] and [(RCp)Rh(C(2)H(4))(2)], respectively, and 1.Eleven metal stabilized [4.8](3)cyclacene derivatives were synthesized. The substances were prepared in one-pot reactions by irradiation of a solution of 5,6,11,12-tetradehydro-dibenzo[a,e]cyclooctatetraene and the corresponding cobalt reagents or rhodium compounds. The resulting cyclacene derivatives reveal D(3h) symmetry in solution. In the solid state the hoop shaped systems crystallize in layers, which are intercalated with solvent layers. To unravel the mechanism of the one-pot reaction we isolated an intermediate, which shows almost planar cyclooctatetraene rings.

  13. 互联网络RCP(n)的路由算法%Routing algorithms on interconnection networks RCP(n)

    Institute of Scientific and Technical Information of China (English)

    刘宏英; 高太平

    2008-01-01

    在对互联网络RCP(Ringed Crossed cube Petersen)拓扑结构研究的基础上,利用RCP(n)网络具有正则性,良好的可扩展性,以及具有比Qn、HP(n)、RHP(n)网络更短的直径和更小的构造开销这些特性,给出了RCP(n)的单播路由算法和广播路由算法,并证明了RCP(n)比Qn、HP(n)、RHP(n)网络具有更好的路由性能.

  14. Von Roll RCP method - first experiences; Von Roll RCP - Verfahren. Erste Erfahrungen

    Energy Technology Data Exchange (ETDEWEB)

    Capitaine, P.; Engweiler, J. [Roll Umwelttechnik AG, Zuerich (Switzerland)

    1998-09-01

    The RCP method was designed as a residue-optimised alternative to the thermally optimised grate firing of residual wastes. Its technical realisation and development to market maturity took no more than 5 years. In the first process stage the waste is converted to high-carbon pyrolysis charcoal and high-rank gas in the absence of oxygen. In the second stage these substances are oxidised by addition of oxygen. The resulting temperature causes the non-combustible constituents of the slag to melt. In a third, optional, stage this molten slag can be liberated of (heavy) metals to such an extent that it can subsequently be used directly as additive for grinding. Further exhaust gas treatment is facilitated by the use of a circulatory fluidised-bed secondary combustion chamber. Despite the reduced flue gas volume and resultant higher pollutant concentrations in the crude gas, overall emissions are lower than in conventional plants. [Deutsch] Das reststoffoptimierte RCP Verfahren ist als Alternative zur thermisch optimierten Rostverbrennung von Restabfaellen konzipiert. In nur fuenf Jahren wurde das Verfahren technisch umgesetzt und zur Marktreife entwickelt. In einer ersten Stufe des Verfahrens wird der Abfall unter Luftabschluss in einen kohlenstoffreichen Pyrolysekoks und eine heizwertreiches Gas umgesetzt. Im zweiten Schritt werden diese Stoffe unter Zugabe von Sauerstoff oxidiert. Dabei treten Temperaturen auf, bei denen die nichtbrennbaren Bestandteile der Schlacke schmelzen. Optional wird diese Schmelzschlacke in einem dritten Schritt derart von (Schwer-) Metallen befreit, dass sie anschliessend direkt als Zement-Zumahlstoff eingesetzt werden kann. Die Nutzung der zirkulierenden Wirbelschicht - Nachbrennkammer zur Abgasbehandlung vereinfacht die weitergehende Abgasbehandlung. Trotz verringertem Rauchgasvolumen und damit hoeheren Schadstoffkonzentrationen im Rohgas werden die Gesamtemissionen gegenueber konventionellen Anlagen verringert. (orig./SR)

  15. Role of CGRP-Receptor Component Protein (RCP) in CLR/RAMP Function

    OpenAIRE

    Dickerson, Ian M.

    2013-01-01

    The receptor for calcitonin gene-related peptide (CGRP) and adrenomedullin (AM) requires an intracellular peripheral membrane protein named CGRP-receptor component protein (RCP) for signaling. RCP is required for CGRP and AM receptor signaling, and it has recently been discovered that RCP enables signaling by binding directly to the receptor. RCP is present in most immortalized cell lines, but in vivo RCP expression is limited to specific subsets of cells, usually co-localizing with CGRP-cont...

  16. Connecting Artificial Brains to Robots in a Comprehensive Simulation Framework: The Neurorobotics Platform

    Science.gov (United States)

    Falotico, Egidio; Vannucci, Lorenzo; Ambrosano, Alessandro; Albanese, Ugo; Ulbrich, Stefan; Vasquez Tieck, Juan Camilo; Hinkel, Georg; Kaiser, Jacques; Peric, Igor; Denninger, Oliver; Cauli, Nino; Kirtay, Murat; Roennau, Arne; Klinker, Gudrun; Von Arnim, Axel; Guyot, Luc; Peppicelli, Daniel; Martínez-Cañada, Pablo; Ros, Eduardo; Maier, Patrick; Weber, Sandro; Huber, Manuel; Plecher, David; Röhrbein, Florian; Deser, Stefan; Roitberg, Alina; van der Smagt, Patrick; Dillman, Rüdiger; Levi, Paul; Laschi, Cecilia; Knoll, Alois C.; Gewaltig, Marc-Oliver

    2017-01-01

    Combined efforts in the fields of neuroscience, computer science, and biology allowed to design biologically realistic models of the brain based on spiking neural networks. For a proper validation of these models, an embodiment in a dynamic and rich sensory environment, where the model is exposed to a realistic sensory-motor task, is needed. Due to the complexity of these brain models that, at the current stage, cannot deal with real-time constraints, it is not possible to embed them into a real-world task. Rather, the embodiment has to be simulated as well. While adequate tools exist to simulate either complex neural networks or robots and their environments, there is so far no tool that allows to easily establish a communication between brain and body models. The Neurorobotics Platform is a new web-based environment that aims to fill this gap by offering scientists and technology developers a software infrastructure allowing them to connect brain models to detailed simulations of robot bodies and environments and to use the resulting neurorobotic systems for in silico experimentation. In order to simplify the workflow and reduce the level of the required programming skills, the platform provides editors for the specification of experimental sequences and conditions, environments, robots, and brain–body connectors. In addition to that, a variety of existing robots and environments are provided. This work presents the architecture of the first release of the Neurorobotics Platform developed in subproject 10 “Neurorobotics” of the Human Brain Project (HBP).1 At the current state, the Neurorobotics Platform allows researchers to design and run basic experiments in neurorobotics using simulated robots and simulated environments linked to simplified versions of brain models. We illustrate the capabilities of the platform with three example experiments: a Braitenberg task implemented on a mobile robot, a sensory-motor learning task based on a robotic controller

  17. Towards a cross-platform software framework to support end-to-end hydrometeorological sensor network deployment

    Science.gov (United States)

    Celicourt, P.; Sam, R.; Piasecki, M.

    2016-12-01

    Global phenomena such as climate change and large scale environmental degradation require the collection of accurate environmental data at detailed spatial and temporal scales from which knowledge and actionable insights can be derived using data science methods. Despite significant advances in sensor network technologies, sensors and sensor network deployment remains a labor-intensive, time consuming, cumbersome and expensive task. These factors demonstrate why environmental data collection remains a challenge especially in developing countries where technical infrastructure, expertise and pecuniary resources are scarce. In addition, they also demonstrate the reason why dense and long-term environmental data collection has been historically quite difficult. Moreover, hydrometeorological data collection efforts usually overlook the (critically important) inclusion of a standards-based system for storing, managing, organizing, indexing, documenting and sharing sensor data. We are developing a cross-platform software framework using the Python programming language that will allow us to develop a low cost end-to-end (from sensor to publication) system for hydrometeorological conditions monitoring. The software framework contains provision for sensor, sensor platforms, calibration and network protocols description, sensor programming, data storage, data publication and visualization and more importantly data retrieval in a desired unit system. It is being tested on the Raspberry Pi microcomputer as end node and a laptop PC as the base station in a wireless setting.

  18. An Experience of Thermowell Design in RCP Test Facility

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Y. S.; Kim, B. D.; Youn, Y. J.; Jeon, W. J.; Kim, S.; Bae, B. U.; Cho, Y. J.; Choi, H. S.; Park, J. K; Cho, S. [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-10-15

    Flow rates for the test should vary in the range of 90% to 130% of rated flowrate under prototypic operational conditions, as shown in Table 1. Generally for the flow control, a combination of a control valve and an orifice was used in previous RCP test facilities. From the commissioning startup of the RCP test facility, it was found the combination of valve and orifice induced quite a large vibration for the RCP. As a solution to minimize the vibration and to facilitate the flowrate control, one of KAERI's staff suggested a variable restriction orifice (VRO), which controls most of the required flowrates except highest flowrates, as shown in Fig. 2. For the highest flowrates, e.g., around run-out flowrate (130%), control valves in bypass lines were also used to achieve required flowrates. From a performance test, it was found the VRO is very effective measures to control flowrates in the RCP test facility. During the commissioning startup operation, one of thermowells located at the upstream of the RCP was cracked due to high speed coolant velocity, which was - fortunately - found under a leakage test before running the RCP test loop. The cracked thermowell, whose tapered-shank was detached from the weld collar after uninstalling, is shown in Fig. 3. As can be seen the figure, most of the cross-section at the root of the thermowell shank was cracked. In this paper, an investigation of the integrity of thermowells in the RCP test facility was performed according to the current code and overall aspects on the thermowell designs were also discussed. An RCP test facility has been constructed in KAERI. During the commissioning startup operation, one of thermowells was cracked due to high speed coolant velocity. To complete the startup operation, a modified design of thermowells was proposed and all the original thermowells were replaced by the modified ones. From evaluation of the original and modified designs of thermowells according to the recent PTC code, the

  19. Exploration of a digital audio processing platform using a compositional system level performance estimation framework

    DEFF Research Database (Denmark)

    Tranberg-Hansen, Anders Sejer; Madsen, Jan

    2009-01-01

    This paper presents the application of a compositional simulation based system-level performance estimation framework on a non-trivial industrial case study. The case study is provided by the Danish company Bang & Olufsen ICEpower a/s and focuses on the exploration of a digital mobile audio...

  20. A Volunteered Geographic Information Framework to Enable Bottom-Up Disaster Management Platforms

    Directory of Open Access Journals (Sweden)

    Mohammad Ebrahim Poorazizi

    2015-08-01

    Full Text Available Recent disasters, such as the 2010 Haiti earthquake, have drawn attention to the potential role of citizens as active information producers. By using location-aware devices such as smartphones to collect geographic information in the form of geo-tagged text, photos, or videos, and sharing this information through online social media, such as Twitter, citizens create Volunteered Geographic Information (VGI. To effectively use this information for disaster management, we developed a VGI framework for the discovery of VGI. This framework consists of four components: (i a VGI brokering module to provide a standard service interface to retrieve VGI from multiple resources based on spatial, temporal, and semantic parameters; (ii a VGI quality control component, which employs semantic filtering and cross-referencing techniques to evaluate VGI; (iii a VGI publisher module, which uses a service-based delivery mechanism to disseminate VGI, and (iv a VGI discovery component to locate, browse, and query metadata about available VGI datasets. In a case study we employed a FOSS (Free and Open Source Software strategy, open standards/specifications, and free/open data to show the utility of the framework. We demonstrate that the framework can facilitate data discovery for disaster management. The addition of quality metrics and a single aggregated source of relevant crisis VGI will allow users to make informed policy choices that could save lives, meet basic humanitarian needs earlier, and perhaps limit environmental and economic damage.

  1. Olsalazine-Based Metal–Organic Frameworks as Biocompatible Platforms for H 2 Adsorption and Drug Delivery

    Energy Technology Data Exchange (ETDEWEB)

    Levine, Dana J.; Runčevski, Tomče; Kapelewski, Matthew T.; Keitz, Benjamin K.; Oktawiec, Julia; Reed, Douglas A.; Mason, Jarad A.; Jiang, Henry Z. H.; Colwell, Kristen A.; Legendre, Christina M.; FitzGerald, Stephen A.; Long, Jeffrey R.

    2016-08-17

    The drug olsalazine (H4olz) was employed as a ligand to synthesize a new series of mesoporous metal–organic frameworks that are expanded analogues of the well-known M2(dobdc) materials (dobdc4– = 2,5-dioxido-1,4-benzenedicarboxylate; M-MOF-74). The M2(olz) frameworks (M = Mg, Fe, Co, Ni, and Zn) exhibit high surface areas with large hexagonal pore apertures that are approximately 27 Å in diameter. Variable temperature H2 adsorption isotherms revealed strong adsorption at the open metal sites, and in situ infrared spectroscopy experiments on Mg2(olz) and Ni2(olz) were used to determine site-specific H2 binding enthalpies. In addition to its capabilities for gas sorption, the highly biocompatible Mg2(olz) framework was also evaluated as a platform for the delivery of olsalazine and other encapsulated therapeutics. The Mg2(olz) material (86 wt % olsalazine) was shown to release the therapeutic linker through dissolution of the framework under simulated physiological conditions. Furthermore, Mg2(olz) was used to encapsulate phenethylamine (PEA), a model drug for a broad class of bioactive compounds. Under simulated physiological conditions, Mg2(olz)(PEA)2 disassembled to release PEA from the pores and olsalazine from the framework itself, demonstrating that multiple therapeutic components can be delivered together at different rates. The low toxicity, high surface areas, and coordinatively unsaturated metal sites make these M2(olz) materials promising for a range of potential applications, including drug delivery in the treatment of gastrointestinal diseases.

  2. Olsalazine-Based Metal-Organic Frameworks as Biocompatible Platforms for H2 Adsorption and Drug Delivery.

    Science.gov (United States)

    Levine, Dana J; Runčevski, Tomče; Kapelewski, Matthew T; Keitz, Benjamin K; Oktawiec, Julia; Reed, Douglas A; Mason, Jarad A; Jiang, Henry Z H; Colwell, Kristen A; Legendre, Christina M; FitzGerald, Stephen A; Long, Jeffrey R

    2016-08-17

    The drug olsalazine (H4olz) was employed as a ligand to synthesize a new series of mesoporous metal-organic frameworks that are expanded analogues of the well-known M2(dobdc) materials (dobdc(4-) = 2,5-dioxido-1,4-benzenedicarboxylate; M-MOF-74). The M2(olz) frameworks (M = Mg, Fe, Co, Ni, and Zn) exhibit high surface areas with large hexagonal pore apertures that are approximately 27 Å in diameter. Variable temperature H2 adsorption isotherms revealed strong adsorption at the open metal sites, and in situ infrared spectroscopy experiments on Mg2(olz) and Ni2(olz) were used to determine site-specific H2 binding enthalpies. In addition to its capabilities for gas sorption, the highly biocompatible Mg2(olz) framework was also evaluated as a platform for the delivery of olsalazine and other encapsulated therapeutics. The Mg2(olz) material (86 wt % olsalazine) was shown to release the therapeutic linker through dissolution of the framework under simulated physiological conditions. Furthermore, Mg2(olz) was used to encapsulate phenethylamine (PEA), a model drug for a broad class of bioactive compounds. Under simulated physiological conditions, Mg2(olz)(PEA)2 disassembled to release PEA from the pores and olsalazine from the framework itself, demonstrating that multiple therapeutic components can be delivered together at different rates. The low toxicity, high surface areas, and coordinatively unsaturated metal sites make these M2(olz) materials promising for a range of potential applications, including drug delivery in the treatment of gastrointestinal diseases.

  3. The nature of the British soldier : warrior or weapons platform a philosophical framework

    OpenAIRE

    McCormack, P J

    2016-01-01

    This thesis is an examination of how the nature of the British soldier is constructed/imagined in contemporary British society if a spectrum of meaning is imagined that posits a warrior existing at one extreme and a weapons platform at the other. Located within a philosophical setting and indebted to Charles Taylor’s modern social imaginaries, a number of sub-questions function as the mechanism used to explore the thesis question in the six research chapters which are: 2, Identity and Narrati...

  4. RCP 钢筋混凝土管检测技术%On testing technique of RCP reinforced concrete pipes

    Institute of Scientific and Technical Information of China (English)

    焦利敏

    2016-01-01

    The paper introduces the testing programs of RCP reinforced concrete pipes,illustrates its testing points from the outline quality,geo-metric dimensioning,compressive strength,and internal water pressure,and points out the test evaluation for the reinforced concrete pipes,so as to be meaningful for the improvement of the drainage pipe quality.%介绍了 RCP 钢筋混凝土管的检测项目,从外观质量、几何尺寸、抗压强度、内水压力等方面,阐述了 RCP 钢筋混凝土管的检测要点,指出钢筋混凝土管的检测评定,对于提高排水管的质量有重要意义。

  5. The Role of Cgrp-Receptor Component Protein (Rcp) in Cgrp-Mediated Signal Transduction

    OpenAIRE

    Prado, M.A.; B. Evans-Bain; Santi, S. L.; Dickerson, I M

    2001-01-01

    The calcitonin gene-related peptide (CGRP)-receptor component protein (RCP) is a 17-kDa intracellular peripheral membrane protein required for signal transduction at CGRP receptors. To determine the role of RCP in CGRP-mediated signal transduction, RCP was depleted from NIH3T3 cells using antisense strategy. Loss of RCP protein correlated with loss of cAMP production by CGRP in the antisense cells. In contrast, loss of RCP had no effect on CGRP-mediated binding; therefore RCP is not acting as...

  6. GridPACK™ : A Framework for Developing Power Grid Simulations on High-Performance Computing Platforms

    Energy Technology Data Exchange (ETDEWEB)

    Palmer, Bruce J.; Perkins, William A.; Chen, Yousu; Jin, Shuangshuang; Callahan, David; Glass, Kevin A.; Diao, Ruisheng; Rice, Mark J.; Elbert, Stephen T.; Vallem, Mallikarjuna R.; Huang, Zhenyu

    2016-05-01

    This paper describes the GridPACK™ framework, which is designed to help power grid engineers develop modeling software capable of running on high performance computers. The framework makes extensive use of software templates to provide high level functionality while at the same time allowing developers the freedom to express whatever models and algorithms they are using. GridPACK™ contains modules for setting up distributed power grid networks, assigning buses and branches with arbitrary behaviors to the network, creating distributed matrices and vectors and using parallel linear and non-linear solvers to solve algebraic equations. It also provides mappers to create matrices and vectors based on properties of the network and functionality to support IO and to mana

  7. The BioIntelligence Framework: a new computational platform for biomedical knowledge computing.

    Science.gov (United States)

    Farley, Toni; Kiefer, Jeff; Lee, Preston; Von Hoff, Daniel; Trent, Jeffrey M; Colbourn, Charles; Mousses, Spyro

    2013-01-01

    Breakthroughs in molecular profiling technologies are enabling a new data-intensive approach to biomedical research, with the potential to revolutionize how we study, manage, and treat complex diseases. The next great challenge for clinical applications of these innovations will be to create scalable computational solutions for intelligently linking complex biomedical patient data to clinically actionable knowledge. Traditional database management systems (DBMS) are not well suited to representing complex syntactic and semantic relationships in unstructured biomedical information, introducing barriers to realizing such solutions. We propose a scalable computational framework for addressing this need, which leverages a hypergraph-based data model and query language that may be better suited for representing complex multi-lateral, multi-scalar, and multi-dimensional relationships. We also discuss how this framework can be used to create rapid learning knowledge base systems to intelligently capture and relate complex patient data to biomedical knowledge in order to automate the recovery of clinically actionable information.

  8. Musrfit: A Free Platform-Independent Framework for μSR Data Analysis

    Science.gov (United States)

    Suter, A.; Wojek, B. M.

    Afree data-analysis framework forμSR has been developed. musrfit is fully written in C++, is running under GNU/Linux, MacOSX, as well as Microsoft Windows, andis distributed under the termsof the GNU GPL.Itis based on the CERN ROOT framework and is utilizing the Minuit2 optimization routines for fitting. It consists of a set of programmes allowing the user to analyze and visualize the data.The fitting process is controlled by an ASCII-input file with an extended syntax. A dedicated text editoris helping the user to createand handle these files in an efficient way, execute the fitting, show the data, get online help, and so on. Aversatile tool for the generation of new input files and the extraction of fit parameters is provided as well. musrfit facilitates a plugin mechanism allowing to invoke user-defined functions. Hence, the functionality of the framework can be extended with a minimal amount of overhead for the user. Currently, musrfit can read the followingfacility raw-data files: PSI-BIN, MDU (PSI), ROOT (LEM/PSI), WKM (outdated ASCII format), MUD (TRIUMF), NeXus (ISIS).

  9. musrfit: A free platform-independent framework for muSR data analysis

    CERN Document Server

    Suter, A

    2011-01-01

    A free data-analysis framework for muSR has been developed. musrfit is fully written in C++, is running under GNU/Linux, Mac OS X, as well as Microsoft Windows, and is distributed under the terms of the GNU GPL. It is based on the CERN ROOT framework and is utilizing the Minuit optimization routines for fitting. It consists of a set of programs allowing the user to analyze and visualize the data. The fitting process is controlled by an ascii-input file with an extended syntax. A dedicated text editor is helping the user to create and handle these files in an efficient way, execute the fitting, show the data, get online help, and so on. A versatile tool for the generation of new input files and the extraction of fit parameters is provided as well. musrfit facilitates a plugin mechanism allowing to invoke user-defined functions. Hence, the functionality of the framework can be extended with a minimal amount of overhead for the user. Currently, musrfit can read the following facility raw-data files: PSI-BIN, MDU...

  10. A series of isoreticular chiral metal-organic frameworks as a tunable platform for asymmetric catalysis.

    Science.gov (United States)

    Ma, Liqing; Falkowski, Joseph M; Abney, Carter; Lin, Wenbin

    2010-10-01

    Metal-organic frameworks, built by bridging metal ions with organic linkers, represent a new class of porous hybrid materials with attractive tunability in compositions, structures and functions. In particular, the mild conditions typically employed for their synthesis allow for the functionalization of their building blocks, and thus the rational design of novel materials. Here we demonstrate the systematic design of eight mesoporous chiral metal-organic frameworks, with the framework formula [LCu2(solvent)2] (where L is a chiral tetracarboxylate ligand derived from 1,1'-bi-2-naphthol), that have the same structures but channels of different sizes. Chiral Lewis acid catalysts were generated by postsynthesis functionalization with Ti(OiPr)4, and the resulting materials proved to be highly active asymmetric catalysts for diethylzinc and alkynylzinc additions, which converted aromatic aldehydes into chiral secondary alcohols. The enantioselectivities of these reactions can be modified by tuning the size of the channels, which alters the diffusion rates of the organic substrates.

  11. OPR1000 RCP Flow Coastdown Analysis using SPACE Code

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Dong-Hyuk; Kim, Seyun [KHNP CRI, Daejeon (Korea, Republic of)

    2016-10-15

    The Korean nuclear industry developed a thermal-hydraulic analysis code for the safety analysis of PWRs, named SPACE(Safety and Performance Analysis Code for Nuclear Power Plant). Current loss of flow transient analysis of OPR1000 uses COAST code to calculate transient RCS(Reactor Coolant System) flow. The COAST code calculates RCS loop flow using pump performance curves and RCP(Reactor Coolant Pump) inertia. In this paper, SPACE code is used to reproduce RCS flowrates calculated by COAST code. The loss of flow transient is transient initiated by reduction of forced reactor coolant circulation. Typical loss of flow transients are complete loss of flow(CLOF) and locked rotor(LR). OPR1000 RCP flow coastdown analysis was performed using SPACE using simplified nodalization. Complete loss of flow(4 RCP trip) was analyzed. The results show good agreement with those from COAST code, which is CE code for calculating RCS flow during loss of flow transients. Through this study, we confirmed that SPACE code can be used instead of COAST code for RCP flow coastdown analysis.

  12. Prevention validation and accounting platform: a framework for establishing accountability and performance measures of substance abuse prevention programs.

    Science.gov (United States)

    Kim, S; McLeod, J H; Williams, C; Hepler, N

    2000-01-01

    The field of substance abuse prevention has neither an overarching conceptual framework nor a set of shared terminologies for establishing the accountability and performance outcome measures of substance abuse prevention services rendered. Hence, there is a wide gap between what we currently have as data on one hand and information that are required to meet the performance goals and accountability measures set by the Government Performance and Results Act of 1993 on the other. The task before us is: How can we establish the accountability and performance measures of substance abuse prevention programs and transform the field of prevention into prevention science? The intent of this volume is to serve that purpose and accelerate the processes of this transformation by identifying the requisite components of the transformation (i.e., theory, methodology, convention on terms, and data) and by introducing an open forum called, Prevention Validation and Accounting (PREVA) Platform. The entire PREVA Platform (for short, the Platform) is designed as an analytic framework, which is formulated by a collectivity of common concepts, terminologies, accounting units, protocols for counting the units, data elements, and operationalizations of various constructs, and other summary measures intended to bring about an efficient and effective measurement of process input, program capacity, process output, performance outcome, and societal impact of substance abuse prevention programs. The measurement units and summary data elements are designed to be measured across time and across jurisdictions, i.e., from local to regional to state to national levels. In the Platform, the process input is captured by two dimensions of time and capital. Time is conceptualized in terms of service delivery time and time spent for research and development. Capital is measured by the monies expended for the delivery of program activities during a fiscal or reporting period. Program capacity is captured

  13. Mesoporous silica nanoparticles with organo-bridged silsesquioxane framework as innovative platforms for bioimaging and therapeutic agent delivery.

    Science.gov (United States)

    Du, Xin; Li, Xiaoyu; Xiong, Lin; Zhang, Xueji; Kleitz, Freddy; Qiao, Shi Zhang

    2016-06-01

    Mesoporous silica material with organo-bridged silsesquioxane frameworks is a kind of synergistic combination of inorganic silica, mesopores and organics, resulting in some novel or enhanced physicochemical and biocompatible properties compared with conventional mesoporous silica materials with pure Si-O composition. With the rapid development of nanotechnology, monodispersed nanoscale periodic mesoporous organosilica nanoparticles (PMO NPs) and organo-bridged mesoporous silica nanoparticles (MSNs) with various organic groups and structures have recently been synthesized from 100%, or less, bridged organosilica precursors, respectively. Since then, these materials have been employed as carrier platforms to construct bioimaging and/or therapeutic agent delivery nanosystems for nano-biomedical application, and they demonstrate some unique and/or enhanced properties and performances. This review article provides a comprehensive overview of the controlled synthesis of PMO NPs and organo-bridged MSNs, physicochemical and biocompatible properties, and their nano-biomedical application as bioimaging agent and/or therapeutic agent delivery system.

  14. Distributed Caching in a Multi-Server Environment : A study of Distributed Caching mechanisms and an evaluation of Distributed Caching Platforms available for the .NET Framework

    OpenAIRE

    Herber, Robert

    2010-01-01

    This paper discusses the problems Distributed Caching can be used to solve and evaluates a couple of Distributed Caching Platforms targeting the .NET Framework. Basic concepts and functionality that is general for all distributed caching platforms is covered in chapter 2. We discuss how Distributed Caching can resolve synchronization problems when using multiple local caches, how a caching tier can relieve the database and improve the scalability of the system, and also how memory consumption...

  15. Future ozone and oxidants change under the RCP scenarios

    Science.gov (United States)

    Kim, Minjoong J.; Park, Rokjin J.; Ho, Chang-Hoi; Woo, Jung-Hun; Choi, Ki-Chul; Song, Chang-Keun; Lee, Jae-Bum

    2015-01-01

    We investigate ozone air quality changes in 2050 caused by global changes in climate and anthropogenic emissions of ozone precursors by using a global chemical transport model driven by meteorological fields from a general circulation model. We use projected emissions based on the Representative Concentration Pathway (RCP) scenarios and conduct model simulations to quantify the effects of climate and emission changes on future air quality, focusing on ozone in surface air. Our model results show that annual mean concentrations of surface ozone will be lower in 2050 relative to 2000 by -3.3, -3.7, and -4.2 ppbv under RCP6.0, RCP4.5, and RCP2.6, respectively. In contrast, the RCP8.5 projection results in a slight increase of 2.1 ppbv caused by a methane increase. The ozone reductions are driven primarily by decreases in NOx emission, which dominate the climate penalty on ozone driven by temperature increases. We also estimate the effect of 21st century climate change on ozone air quality, assuming no changes in anthropogenic emissions of ozone precursors in the future. We further use a statistical method to analyze the results in order to quantify the effect of each meteorological variable change on ozone concentration in summer. Temperature increase is found to result in ozone increases of up to 2.2 ppbv over land. Ozone over the oceans, however, is largely reduced with specific humidity increase, particularly in the Northern Hemisphere, where the ozone concentration decreases by 0.8 ppbv. We find that future increases in natural NOx emissions from lightning and soil make an important contribution to the formation of nitric acid and might seriously offset future decreases in nitrogen deposition caused by anthropogenic NOx emission reduction.

  16. Protein-Metal Organic Framework Hybrid Composites with Intrinsic Peroxidase-like Activity as a Colorimetric Biosensing Platform.

    Science.gov (United States)

    Yin, Yuqing; Gao, Chen Ling; Xiao, Qi; Lin, Guo; Lin, Zian; Cai, Zongwei; Yang, Huang-Hao

    2016-10-04

    Artificial enzyme mimetics have received considerable attention because natural enzymes have some significant drawbacks, including enzyme autolysis, low catalytic activity, poor recovery and low stability to environmental changes. Herein, we demonstrated a facile approach for one-pot synthesis of hemeprotein-metal organic framework hybrid composites (H-MOFs) by using bovine hemoglobin (BHb) and zeolitic imidazolate framework-8 (ZIF-8) as a model reaction system. Surprisingly, the new hybrid composites exhibits 423% increase in peroxidase-like catalytic activity compared to free BHb. Taking advantages of the unique pore structure of H-MOFs with high catalytic property, a H-MOFs-based colorimetric biosensing platform was newly constructed and applied for the fast and sensitive detection of hydrogen peroxide (H2O2) and phenol. The corresponding detection limits as low as 1.0 μM for each analyte with wide linear ranges (0-800 μM for H2O2 and 0-200 μM for phenol) were obtained by naked-eye visualization. Significantly, sensitive and selective method for visual assay of trace H2O2 in cell and phenol in sewage was achieved with this platform. The stability of H-MOFs was also examined and excellent reproducibility and recyclability without losing in its activity were observed. In addition, the general applicability of H-MOFs was also investigated by using other hemeproteins (horseradish peroxidase, and myoglobin) and the corresponding catalytic activities were 291% and 273% enhancement, respectively. This present work not only expands the application of MOFs, but also provides an alternative technique for biological and environmental sample assay.

  17. Magnetic porous carbon nanocomposites derived from metal-organic frameworks as a sensing platform for DNA fluorescent detection.

    Science.gov (United States)

    Tan, Hongliang; Tang, Gonge; Wang, Zhixiong; Li, Qian; Gao, Jie; Wu, Shimeng

    2016-10-12

    Metal-organic frameworks (MOFs) have emerged as very fascinating functional materials due to their tunable nature and diverse applications. In this work, we prepared a magnetic porous carbon (MPC) nanocomposite by employing iron-containing MOFs (MIL-88A) as precursors through a one-pot thermolysis method. It was found that the MPC can absorb selectively single-stranded DNA (ssDNA) probe to form MPC/ssDNA complex and subsequently quench the labelled fluorescent dye of the ssDNA probe, which is resulted from the synergetic effect of magnetic nanoparticles and carbon matrix. Upon the addition of complementary target DNA, however, the absorbed ssDNA probe could be released from MPC surface by forming double-stranded DNA with target DNA, and accompanied by the recovery of the fluorescence of ssDNA probe. Based on these findings, a sensing platform with low background signal for DNA fluorescent detection was developed. The proposed sensing platform exhibits high sensitivity with detection limit of 1 nM and excellent selectivity to specific target DNA, even single-base mismatched nucleotide can be distinguished. We envision that the presented study would provide a new perspective on the potential applications of MOF-derived nanocomposites in biomedical fields. Copyright © 2016 Elsevier B.V. All rights reserved.

  18. 3D metal-organic framework as highly efficient biosensing platform for ultrasensitive and rapid detection of bisphenol A.

    Science.gov (United States)

    Wang, Xue; Lu, Xianbo; Wu, Lidong; Chen, Jiping

    2015-03-15

    As is well known, bisphenol A (BPA), usually exists in daily plastic products, is one of the most important endocrine disrupting chemicals. In this work, copper-centered metal-organic framework (Cu-MOF) was synthesized, which was characterized by SEM, TEM, XRD, FTIR and electrochemical method. The resultant Cu-MOF was explored as a robust electrochemical biosensing platform by choosing tyrosinase (Tyr) as a model enzyme for ultrasensitive and rapid detection of BPA. The Cu-MOF provided a 3D structure with a large specific surface area, which was beneficial for enzyme and BPA absorption, and thus improved the sensitivity of the biosensor. Furthermore, Cu-MOF as a novel sorbent could increase the available BPA concentration to react with tyrosinase through π-π stacking interactions between BPA and Cu-MOF. The Tyr biosensor exhibited a high sensitivity of 0.2242A M(-1) for BPA, a wide linear range from 5.0×10(-8) to 3.0×10-6moll(-1), and a low detection limit of 13nmoll(-1). The response time for detection of BPA is less than 11s. The proposed method was successfully applied to rapid and selective detection of BPA in plastic products with satisfactory results. The recoveries are in the range of 94.0-101.6% for practical applications. With those remarkable advantages, MOFs-based 3D structures show great prospect as robust biosensing platform for ultrasensitive and rapid detection of BPA.

  19. The Role of Cgrp-Receptor Component Protein (Rcp in Cgrp-Mediated Signal Transduction

    Directory of Open Access Journals (Sweden)

    M. A. Prado

    2001-01-01

    Full Text Available The calcitonin gene-related peptide (CGRP-receptor component protein (RCP is a 17-kDa intracellular peripheral membrane protein required for signal transduction at CGRP receptors. To determine the role of RCP in CGRP-mediated signal transduction, RCP was depleted from NIH3T3 cells using antisense strategy. Loss of RCP protein correlated with loss of cAMP production by CGRP in the antisense cells. In contrast, loss of RCP had no effect on CGRP-mediated binding; therefore RCP is not acting as a chaperone for the CGRP receptor. Instead, RCP is a novel signal transduction molecule that couples the CGRP receptor to the cellular signal transduction machinery. RCP thus represents a prototype for a new class of signal transduction proteins that are required for regulation of G protein-coupled receptors.

  20. Metal–Organic Frameworks as Platforms for the Controlled Nanostructuring of Single-Molecule Magnets

    Energy Technology Data Exchange (ETDEWEB)

    Aulakh, Darpandeep; Pyser, Joshua B.; Zhang, Xuan; Yakovenko, Andrey A.; Dunbar, Kim R.; Wriedt, Mario

    2015-07-29

    The prototypical SMM molecule [Mn12O12(O2CCH3)16(OH2)4] was incorporated under mild conditions into a highly porous metal-organic framework (MOF) matrix as a proof of principle for controlled nanostructuring of SMMs. Four independent experiments revealed that the SMM clusters were successfully loaded in the MOF pores, namely synchrotron-based powder diffraction, physisorption analysis, and in-depth magnetic and thermal analyses. The results provide incontrovertible evidence that the magnetic composite, SMM@MOF, combines key SMM properties with the functional properties of MOFs. Most importantly, the incorporated SMMs exhibit a significant enhanced thermal stability with SMM loading advantageously occurring at the periphery of the bulk MOF crystals with only a single SMM molecule isolated in the transverse direction of the pores.

  1. Separation of C2 Hydrocarbons by Porous Materials: Metal Organic Frameworks as Platform

    Energy Technology Data Exchange (ETDEWEB)

    Banerjee, Debasis; Liu, Jun; Thallapally, Praveen K.

    2014-12-22

    The effective separation of small hydrocarbon molecules (C1 – C4) is an important process for petroleum industry, determining the end price of many essential commodities in our daily lives. Current technologies for separation of these molecules rely on energy intensive fractional distillation processes at cryogenic temperature, which is particularly difficult because of their similar volatility. In retrospect, adsorptive separation using solid state adsorbents might be a cost effective alternative. Several types of solid state adsorbents (e.g. zeolite molecular sieves) were tested for separation of small hydrocarbon molecules as a function of pressure, temperature or vacuum. Among different types of plausible adsorbents, metal organic frameworks (MOFs), a class of porous, crystalline, inorganic-organic hybrid materials, is particularly promising. In this brief comment article, we discuss the separation properties of different types of solid state adsorbents, with a particular emphasis on MOF based adsorbents for separation of C2 hydrocarbon molecules.

  2. Fabrication of Palladium Nanoparticles on Porous Aromatic Frameworks as a Sensing Platform to Detect Vanillin.

    Science.gov (United States)

    Vilian, A T Ezhil; Puthiaraj, Pillaiyar; Kwak, Cheol Hwan; Hwang, Seung-Kyu; Huh, Yun Suk; Ahn, Wha-Seung; Han, Young-Kyu

    2016-05-25

    Here, we report the fabrication of palladium nanoparticles on porous aromatic frameworks (Pd/PAF-6) using a facile chemical approach, which was characterized by various spectro- and electrochemical techniques. The differential pulse voltammetry (DPV) response of Pd/PAF-6 toward the vanillin (VA) sensor shows a linear relationship over concentrations (10-820 pM) and a low detection limit (2 pM). Pd/PAF-6 also exhibited good anti-interference performance toward 2-fold excess of ascorbic acid, nitrophenol, glutathione, glucose, uric acid, dopamine, ascorbic acid, 4-nitrophenol, glutathione, glucose, uric acid, dopamine, and 100-fold excess of Na(+), Mg(2+), and K(+) during the detection of VA. The developed electrochemical sensor based on Pd/PAF-6 had good reproducibility, as well as high selectivity and stability. The established sensor revealed that Pd/PAF-6 could be used to detect VA in biscuit and ice cream samples with satisfactory results.

  3. Metal-organic Frameworks as A Tunable Platform for Designing Functional Molecular Materials

    Science.gov (United States)

    Wang, Cheng; Liu, Demin

    2013-01-01

    Metal-organic frameworks (MOFs), also known as coordination polymers, represent an interesting class of crystalline molecular materials that are synthesized by combining metal-connecting points and bridging ligands. The modular nature of and mild conditions for MOF synthesis have permitted the rational structural design of numerous MOFs and the incorporation of various functionalities via constituent building blocks. The resulting designer MOFs have shown promise for applications in a number of areas, including gas storage/separation, nonlinear optics/ferroelectricity, catalysis, energy conversion/storage, chemical sensing, biomedical imaging, and drug delivery. The structure-property relationships of MOFs can also be readily established by taking advantage of the knowledge of their detailed atomic structures, which enables fine-tuning of their functionalities for desired applications. Through the combination of molecular synthesis and crystal engineering MOFs thus present an unprecedented opportunity for the rational and precise design of functional materials. PMID:23944646

  4. Porous metal-organic-framework nanoscale carriers as a potential platform for drug delivery and imaging

    Science.gov (United States)

    Horcajada, Patricia; Chalati, Tamim; Serre, Christian; Gillet, Brigitte; Sebrie, Catherine; Baati, Tarek; Eubank, Jarrod F.; Heurtaux, Daniela; Clayette, Pascal; Kreuz, Christine; Chang, Jong-San; Hwang, Young Kyu; Marsaud, Veronique; Bories, Phuong-Nhi; Cynober, Luc; Gil, Sophie; Férey, Gérard; Couvreur, Patrick; Gref, Ruxandra

    2010-02-01

    In the domain of health, one important challenge is the efficient delivery of drugs in the body using non-toxic nanocarriers. Most of the existing carrier materials show poor drug loading (usually less than 5wt% of the transported drug versus the carrier material) and/or rapid release of the proportion of the drug that is simply adsorbed (or anchored) at the external surface of the nanocarrier. In this context, porous hybrid solids, with the ability to tune their structures and porosities for better drug interactions and high loadings, are well suited to serve as nanocarriers for delivery and imaging applications. Here we show that specific non-toxic porous iron(III)-based metal-organic frameworks with engineered cores and surfaces, as well as imaging properties, function as superior nanocarriers for efficient controlled delivery of challenging antitumoural and retroviral drugs (that is, busulfan, azidothymidine triphosphate, doxorubicin or cidofovir) against cancer and AIDS. In addition to their high loadings, they also potentially associate therapeutics and diagnostics, thus opening the way for theranostics, or personalized patient treatments.

  5. Platform Constellations

    DEFF Research Database (Denmark)

    Staykova, Kalina Stefanova; Damsgaard, Jan

    2016-01-01

    This research paper presents an initial attempt to introduce and explain the emergence of new phenomenon, which we refer to as platform constellations. Functioning as highly modular systems, the platform constellations are collections of highly connected platforms which co-exist in parallel...... and as such allow us to study platforms not only as separate entities, but also to investigate the relationship between several platforms offered and governed by one and the same platform provider. By investigating two case studies of indigenous platform constellations formed around the hugely popular instant...... messaging apps KakaoTalk and LINE, we are able to gain valuable insights about the nature of these new constructions and to capture and synthesize their main characteristics in a framework. Our results show that platform constellations possess unique innovative capabilities, which can improve users...

  6. Ocean Data Interoperability Platform (ODIP): developing a common global framework for marine data management through international collaboration

    Science.gov (United States)

    Glaves, Helen

    2015-04-01

    Marine research is rapidly moving away from traditional discipline specific science to a wider ecosystem level approach. This more multidisciplinary approach to ocean science requires large amounts of good quality, interoperable data to be readily available for use in an increasing range of new and complex applications. Significant amounts of marine data and information are already available throughout the world as a result of e-infrastructures being established at a regional level to manage and deliver marine data to the end user. However, each of these initiatives has been developed to address specific regional requirements and independently of those in other regions. Establishing a common framework for marine data management on a global scale necessitates that there is interoperability across these existing data infrastructures and active collaboration between the organisations responsible for their management. The Ocean Data Interoperability Platform (ODIP) project is promoting co-ordination between a number of these existing regional e-infrastructures including SeaDataNet and Geo-Seas in Europe, the Integrated Marine Observing System (IMOS) in Australia, the Rolling Deck to Repository (R2R) in the USA and the international IODE initiative. To demonstrate this co-ordinated approach the ODIP project partners are currently working together to develop several prototypes to test and evaluate potential interoperability solutions for solving the incompatibilities between the individual regional marine data infrastructures. However, many of the issues being addressed by the Ocean Data Interoperability Platform are not specific to marine science. For this reason many of the outcomes of this international collaborative effort are equally relevant and transferable to other domains.

  7. An Dynamic Realization for Eclipse RCP WizrdPage%Eclipse RCP WizrdPage动态实现方法

    Institute of Scientific and Technical Information of China (English)

    王舜燕; 康磊; 黄莎莉

    2007-01-01

    针对Eclipse RCP WizardPage的静态实现难以解决各输入页间数据关联的功能局限性问题,分析WizardPage的运行机理和动态实现的技术难点,提出一种基于观察者模式的Eclipse RCP WizardPage动态实现方法,使业务对象低耦合,逻辑清晰,为代码维护以及业务扩展奠定良好的基础,最后给出有代表性的需求模型及其实现编码.

  8. Role of CGRP-receptor component protein (RCP) in CLR/RAMP function.

    Science.gov (United States)

    Dickerson, Ian M

    2013-08-01

    The receptor for calcitonin gene-related peptide (CGRP) and adrenomedullin (AM) requires an intracellular peripheral membrane protein named CGRP-receptor component protein (RCP) for signaling. RCP is required for CGRP and AM receptor signaling, and it has recently been discovered that RCP enables signaling by binding directly to the receptor. RCP is present in most immortalized cell lines, but in vivo RCP expression is limited to specific subsets of cells, usually co-localizing with CGRP-containing neurons. RCP protein expression correlates with CGRP efficacy in vivo, suggesting that RCP regulates CGRP signaling in vivo as it does in cell culture. RCP is usually identified in cytoplasm or membranes of cells, but recently has been observed in nucleus of neurons, suggesting an additional transcriptional role for RCP in cell function. Together, these data support an essential role for RCP in CGRP and AM receptor function, in which RCP expression enhances signaling of the CGRP or AM receptor, and therefore increases the efficacy of CGRP and AM in vivo.

  9. THE OLDEST TRIASSIC PLATFORM MARGIN REEF FROM THE ALPINE - CARPATHIAN REGION (AGGTELEK, NE HUNGARY: PLATFORM EVOLUTION, REEFAL BIOTA AND BIOSTRATIGRAPHIC FRAMEWORK

    Directory of Open Access Journals (Sweden)

    FELICITÁSZ VELLEDITS

    2011-07-01

    Full Text Available The 1:10,000 scale mapping of the southern part of the Aggtelek Plateau (Western Carpathians, Silica Nappe, NE Hungary and the study of five sections revealed two Middle Triassic reef bodies. In the late Pelsonian the uniform Steinalm Platform was drowned and dissected due to the Reifling Event. A connection with the open sea was established, indicated by the appearance of gladigondolellid conodonts from the early Illyrian. Basins and highs were formed. In the NW part of the studied area lower - middle? Illyrian basinal carbonates were followed by a platform margin reef (early?-middle Illyrian; reef stage 1 developed on a morphological high. This is the oldest known Triassic platform margin reef within the Alpine-Carpathian region. The reef association is dominated by sphinctozoans and microproblematics. The fossils are characteristic of the Wetterstein-type reef communities.Differently from this in the SE part of the studied region a basin existed from the late Pelsonian until the early Ladinian. During the late Illyrian- early Ladinian, the reef prograded to the SE, and reef stage 2 was established. Meanwhile, on the NW part of the platform a lagoon was formed behind the reef. Based on our palaeontological study the stratigraphic range of Colospongia catenulata, Follicatena cautica, Solenolmia manon manon, Vesicocaulis oenipontanus must be extended down to the middle Illyrian. Synsedimentary tectonics were detected in the 1. Binodosus Subzone, 2. Trinodosus Zone - the most part of the Reitzi Zone, 3. Avisianum Subzone. 

  10. Characterisation of the Rab binding properties of Rab coupling protein (RCP) by site-directed mutagenesis.

    Science.gov (United States)

    Lindsay, Andrew J; McCaffrey, Mary W

    2004-07-30

    Rab coupling protein (RCP) is a member of the Rab11-family of interacting proteins (Rab11-FIPs). Family members are characterised by their ability to interact with Rab11. This property is mediated by a conserved Rab binding domain (RBD) located at their carboxy-termini. Several Rab11-FIPs can also interact with other small GTPases. RCP interacts with Rab4 in addition to Rab11. To dissect out the individual properties of the Rab4 and Rab11 interactions with RCP, conserved amino acids within the RBD of RCP were mutated by site-directed mutagenesis. The effect of these mutations on Rab4 and Rab11 binding, and the intracellular localisation of RCP, was examined. Our results indicate that Rab11, rather than Rab4, mediates the intracellular localisation of RCP, and that the class I Rab11-FIPs compete for binding to Rab11.

  11. Ocean Data Interoperability Platform (ODIP): supporting the development of a common global framework for marine data management through international collaboration

    Science.gov (United States)

    Glaves, Helen; Schaap, Dick; Arko, Robert; Proctor, Roger

    2014-05-01

    Ecosystem level marine research necessitates that large amounts of interoperable data are readily available for use in a wide range of new and complex multidisciplinary applications. Significant amounts of marine data and information are available throughout the world due to the implementation of e-infrastructures at a regional level to manage and deliver this data to the end user. However, each of these initiatives has been developed to address specific regional requirements and independently of those in other regions. To establish a common framework for marine data management on a global scale that supports an ecosystem level approach to marine research there is a need to develop interoperability across these existing data infrastructures. The Ocean Data Interoperability (ODIP) project is creating a co-ordination platform to support collaboration between a number of these existing regional e-infrastructures which include Rolling Deck to Repository (R2R) in the USA, SeaDataNet and Geo-Seas in Europe, IMOS in Australia and also the international IODE initiative. To demonstrate this co-ordinated approach several prototypes will be developed to test and evaluate potential interoperability solutions for solving the incompatibilities identified between the different regional data infrastructures. These prototypes will be used to underpin the development of a common approach to the management of marine data which can also be promoted to the wider marine research community with a view to expanding this framework to include other regional marine data infrastructures. To achieve these objectives relevant domain experts are coming together at a series of workshops where areas of commonality between the regional infrastructures will be identified which can then be used as the foundation for the development of the prototype solutions. As a result six topics are currently being addressed by the ODIP project which have been identified and analysed during the first two ODIP

  12. PENGGUNAAN KRITERIA rcP PADA PEMILIHAN PEUBAH BEBAS TERBAIK JIKA TERDAPAT MULTIKOLINEARITAS

    Directory of Open Access Journals (Sweden)

    Harmi Sugiarti

    2016-09-01

    Full Text Available Some procedures can be used for selecting independent variables, one of them is the procedure of all possible regression with robust Cp (RCp criterion. This statistic is not sensitive with multicollinearity in model and outlier residuals. The aim of this article is to investigate the use of RCp criterion in selecting independent variables. The result of the simulation experimental data shows that the RCp criterion fits enough to select independent variables.

  13. PENGGUNAAN KRITERIA rcP PADA PEMILIHAN PEUBAH BEBAS TERBAIK JIKA TERDAPAT MULTIKOLINEARITAS

    OpenAIRE

    Harmi Sugiarti

    2016-01-01

    Some procedures can be used for selecting independent variables, one of them is the procedure of all possible regression with robust Cp (RCp) criterion. This statistic is not sensitive with multicollinearity in model and outlier residuals. The aim of this article is to investigate the use of RCp criterion in selecting independent variables. The result of the simulation experimental data shows that the RCp criterion fits enough to select independent variables.

  14. Retrograde cerebral perfusion (RCP) in aortic arch surgery: efficacy and possible mechanisms of brain protection.

    Science.gov (United States)

    Bavaria, J E; Pochettino, A

    1997-07-01

    Retrograde cerebral perfusion (RCP) was first introduced to treat air embolism during cardiopulmonary bypass (CPB). Its use was reintroduced to extend the safety of hypothermic circulatory arrest (HCA) during operations involving an open aortic arch. RCP seems to prevent cerebral rewarming during HCA. Both clinical and animal data suggest that RCP provides between 10% and 30% of baseline cerebral blood flow when administered through the superior vena cava (SVC) at jugular pressures of 20 to 25 mm Hg. RCP flows producing jugular venous pressures higher than 30 mm Hg may cause cerebral edema. Cerebral blood flow generated by RCP is able to sustain some cerebral metabolic activity, yet is not able to fully meet cerebral energy demands even at temperatures of 12 degrees to 18 degrees C. RCP may further prevent embolic events during aortic arch surgery when administered at moderate jugular vein pressures (RCP, when applied during aortic arch reconstruction, may extend the safe HCA period and improve morbidity and mortality, especially when HCA times are more than 60 minutes. RCP applied in patients and severe carotid and brachiocephalic occlusive disease may be ineffective, and caution is in order when RCP times are greater than 90 minutes.

  15. 互联网络RCP(n)的组播路由算法%Study on Multicast Routing Algorithm of RCP(n) Interconnection Networks

    Institute of Scientific and Technical Information of China (English)

    刘宏英; 高太平

    2007-01-01

    互联网络RCP(Ringed Crossed cube Petersen)拓扑结构被提出后并没有给出组播算法.本文利用RCP(n)网络的正则性、良好的可扩展性,以及比Qn,HP(n),RHP(n)网络直径更短和构造开销更小这些特性,按照构造组播树的方法,给出了RCP(n)网络的组播路由算法,并对该算法作了性能分析.

  16. Ocean Data Interoperability Platform (ODIP): developing a common framework for marine data management on a global scale

    Science.gov (United States)

    Glaves, Helen; Schaap, Dick

    2016-04-01

    The increasingly ocean basin level approach to marine research has led to a corresponding rise in the demand for large quantities of high quality interoperable data. This requirement for easily discoverable and readily available marine data is currently being addressed by initiatives such as SeaDataNet in Europe, Rolling Deck to Repository (R2R) in the USA and the Australian Ocean Data Network (AODN) with each having implemented an e-infrastructure to facilitate the discovery and re-use of standardised multidisciplinary marine datasets available from a network of distributed repositories, data centres etc. within their own region. However, these regional data systems have been developed in response to the specific requirements of their users and in line with the priorities of the funding agency. They have also been created independently of the marine data infrastructures in other regions often using different standards, data formats, technologies etc. that make integration of marine data from these regional systems for the purposes of basin level research difficult. Marine research at the ocean basin level requires a common global framework for marine data management which is based on existing regional marine data systems but provides an integrated solution for delivering interoperable marine data to the user. The Ocean Data Interoperability Platform (ODIP/ODIP II) project brings together those responsible for the management of the selected marine data systems and other relevant technical experts with the objective of developing interoperability across the regional e-infrastructures. The commonalities and incompatibilities between the individual data infrastructures are identified and then used as the foundation for the specification of prototype interoperability solutions which demonstrate the feasibility of sharing marine data across the regional systems and also with relevant larger global data services such as GEO, COPERNICUS, IODE, POGO etc. The potential

  17. Zeolite-like metal-organic frameworks (ZMOFs) as hydrogen storage platform: lithium and magnesium ion-exchange and H(2)-(rho-ZMOF) interaction studies.

    Science.gov (United States)

    Nouar, Farid; Eckert, Juergen; Eubank, Jarrod F; Forster, Paul; Eddaoudi, Mohamed

    2009-03-04

    Zeolite-like metal-organic frameworks (ZMOFs) are anionic, have readily exchangeable extra-framework cations, and can be constructed with a variety of organic linkers. ZMOFs therefore can be regarded as an excellent platform for systematic studies of the effect(s) of various structural factors on H(2) binding/interaction with porous metal-organic materials. We find that the enhanced binding of molecular hydrogen in ion-exchanged ZMOFs with an anionic framework is largely governed by the presence of the electrostatic field in the cavity, which is reflected by isosteric heats of adsorption in these compounds which are greater by as much as 50% relative to those in neutral MOFs. Direct contact of the sorbed hydrogen with the exchangeable cations is shown not to be possible in the explored systems thus far, as they retain their form as aqua complexes.

  18. An Autonomous Platform Simulator (APS)

    Science.gov (United States)

    1989-06-01

    4 Da~c o! Rcp .’rt’ yeur. :nr.e,1 Page Count Master’s Thesi rmT Ju’ne 1 9 9 Ze 16 Supplementary Notat~on 14 The views expressed in this thesis are...the flight volume is based on the firing platform’s current LOS not the LOS at the time of firing. The near and far clipping planes are set to the

  19. Identification of neotropical felid faeces using RCP-PCR.

    Science.gov (United States)

    Roques, S; Adrados, B; Chavez, C; Keller, C; Magnusson, W E; Palomares, F; Godoy, J A

    2011-01-01

    Faeces similarity among sympatric felid species has generally hampered their use in distributional, demographic and dietary studies. Here, we present a new and simple approach based on a set of species-specific primers, for the unambiguous identification of faeces from sympatric neotropical felids (i.e. puma, jaguar, jaguarundi and ocelot/ margay). This method, referred to as rapid classificatory protocol-PCR (RCP-PCR), consists of a single-tube multiplex PCR yielding species-specific banding patterns on agarose gel. The method was optimized with samples of known origin (14 blood and 15 fresh faeces) and validated in faecal samples of unknown origin (n = 138), for some of which (n = 40) we also obtained species identification based on mtDNA sequencing. This approach proved reliable and provides high identification success rates from faeces. Its simplicity and cost effectiveness should facilitate its application for routine surveys of presence and abundance of these species. © 2010 Blackwell Publishing Ltd.

  20. Ensemble simulations for the RCP8.5-Scenario

    Directory of Open Access Journals (Sweden)

    Friedrich-Wilhelm Gerstengarbe

    2015-04-01

    Full Text Available The mean climatic development for Germany was investigated within the period 2031/60 in comparison to the situation in the observational period 1981/2010. The RCP8.5-Scenario of the IPCC was used because it reflects the actual CO2-emissions very well. On this basis the temperature trend for Germany was estimated using 21 GCM runs up to the year 2100. This temperature trend was the driving force for the statistical regional climate model STARS. 100 ensemble runs of the model STARS were compared with the scenario period and with the observational period. Temperature, precipitation, climatic water balance and some additional parameters were analyzed. One important result is the change in the distribution of precipitation in Germany during the year – decrease in summer, increase in winter. Finally the future climate development leads to a negative climatic water balance over the whole year.

  1. Characterization of the complement inhibitory function of rhesus rhadinovirus complement control protein (RCP).

    Science.gov (United States)

    Okroj, Marcin; Mark, Linda; Stokowska, Anna; Wong, Scott W; Rose, Nicola; Blackbourn, David J; Villoutreix, Bruno O; Spiller, O Brad; Blom, Anna M

    2009-01-02

    Rhesus rhadinovirus (RRV) is currently the closest known, fully sequenced homolog of human Kaposi sarcoma-associated herpesvirus. Both these viruses encode complement inhibitors as follows: Kaposi sarcoma-associated herpesvirus-complement control protein (KCP) and RRV-complement control protein (RCP). Previously we characterized in detail the functional properties of KCP as a complement inhibitor. Here, we performed comparative analyses for two variants of RCP protein, encoded by RRV strains H26-95 and 17577. Both RCP variants and KCP inhibited human and rhesus complement when tested in hemolytic assays measuring all steps of activation via the classical and the alternative pathway. RCP variants from both RRV strains supported C3b and C4b degradation by factor I and decay acceleration of the classical C3 convertase, similar to KCP. Additionally, the 17577 RCP variant accelerated decay of the alternative C3 convertase, which was not seen for KCP. In contrast to KCP, RCP showed no affinity to heparin and is the first described complement inhibitor in which the binding site for C3b/C4b does not interact with heparin. Molecular modeling shows a structural disruption in the region of RCP that corresponds to the KCP-heparin-binding site. This makes RRV a superior model for future in vivo investigations of complement evasion, as RCP does not play a supportive role in viral attachment as KCP does.

  2. European School of Internal Medicine: a window of opportunity for RCP activities in Europe.

    Science.gov (United States)

    Davidson, Chris; Higgens, Clare

    2009-04-01

    The Royal College of Physicians (RCP) is to host the European School of Internal Medicine for two years from 2009-10. This affords a unique opportunity for specialist registrars to exchange ideas about professional development and training and to make contacts with young internists from across Europe. Such links should prove useful for future RCP initiatives in European medicine.

  3. Risk Analyses of Charging Pump Control Improvements for Alternative RCP Seal Cooling

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Eun-Chan [Korea Hydro and Nuclear Power Co. Ltd. Daejeon (Korea, Republic of)

    2015-10-15

    There are two events that significantly affect the plant risk during a TLOCCW event. One is an event in which the seal assembly of a reactor coolant pump (RCP) fails due to heating stress from the loss of cooling water; the other is an event in which the operators fail to conduct alternative cooling for the RCP seal during the accident. KHNP reviewed the replacement of the RCP seal with a qualified shutdown seal in order to remove the risk due to RCP seal failure during a TLOCCW. As an optional measure, a design improvement in the alternative cooling method for the RCP seal is being considered. This analysis presents the alternative RCP seal cooling improvement and its safety effect. K2 is a nuclear power plant with a Westinghouse design, and it has a relatively high CDF during TLOCCW events because it has a different CCW system design and difficulty in preparing alternative cooling water sources. This analysis confirmed that an operator action providing cold water to the RWST as RCP seal injection water during a TLOCCW event is very important in K2. The control circuit improvement plan for the auxiliary charging pump was established in order to reduce the failure probability of this operator action. This analysis modeled the improvement as a fault tree and evaluated the resulting CDF change. The consequence demonstrated that the RCP seal injection failure probability was reduced by 89%, and the CDF decreased by 28%.

  4. The role of the CGRP-receptor component protein (RCP) in adrenomedullin receptor signal transduction.

    Science.gov (United States)

    Prado, M A; Evans-Bain, B; Oliver, K R; Dickerson, I M

    2001-11-01

    G protein-coupled receptors are usually thought to act as monomer receptors that bind ligand and then interact with G proteins to initiate signal transduction. In this study we report an intracellular peripheral membrane protein named the calcitonin gene-related peptide (CGRP)-receptor component protein (RCP) required for signal transduction at the G protein-coupled receptor for adrenomedullin. Cell lines were made that expressed an antisense construct of the RCP cDNA, and in these cells diminished RCP expression correlated with loss of adrenomedullin signal transduction. In contrast, loss of RCP did not diminish receptor density or affinity, therefore RCP does not appear to act as a chaperone protein. Instead, RCP represents a novel class of protein required to couple the adrenomedullin receptor to the cellular signal transduction pathway. A candidate adrenomedullin receptor named the calcitonin receptor-like receptor (CRLR) has been described, which forms high affinity adrenomedullin receptors when co-expressed with the accessory protein receptor-activity modifying protein 2 (RAMP2). RCP co-immunoprecipitated with CRLR and RAMP2, indicating that a functional adrenomedullin receptor is composed of at least three proteins: the ligand binding protein (CRLR), an accessory protein (RAMP2), and a coupling protein for signal transduction (RCP).

  5. The novel Rab11-FIP/Rip/RCP family of proteins displays extensive homo- and hetero-interacting abilities.

    Science.gov (United States)

    Wallace, Deborah M; Lindsay, Andrew J; Hendrick, Alan G; McCaffrey, Mary W

    2002-04-12

    The Rab11-FIP/Rip/RCP proteins are a recently described novel protein family, whose members interact with Rab GTPases that function in endosomal recycling. To date, five such proteins have been described in humans, all of which interact with Rab11, and one (RCP) also interacts with Rab4. Here, we characterise several of these proteins with respect to their ability to interact with Rab4, as well as their ability to self-interact, and to interact with each other. We now demonstrate that two of the family members-pp75/Rip11 and Rab11-FIP3 do not bind Rab4 and show that several members of the family can self-interact and interact with each other. These interactions primarily involve their C-terminal end which includes the Rab binding domain (RBD) that is contained within a predicted coiled-coil, or ERM motif. We identify a new (sixth) member of the protein family, which we propose to name Rab11-FIP4, and report the family evolutionary complexity and chromosomal distribution. Furthermore, we propose that the ability of these proteins to bind each other will be important in effecting membrane trafficking events by forming protein 'platforms,' regulated by Rab11 and/or Rab4 activity.

  6. 基于 RCP 的可扩展性应用平台研究与实现

    Institute of Scientific and Technical Information of China (English)

    黄德瑞; 王秋海

    2012-01-01

      RCP (Rich Client Platform)是基于 Eclipse 开发平台而推出的一套用来开发富客户端程序的应用框架。传统 B/S架构虽然在其程序部署,版本控制等方面有很大的优势,但是 C/S 也具备其独特的优势比如离线处理能力,低服务器负载等等。本文回顾了 Eclipse 以及 RCP 程序的特点,同时对比了基于 B/S 应用的特点。本研究结合 Eclipse 平台的特点提出一种应用于快速开发应用的可拓展性平台。

  7. Test Case Execution Framework Based on Linux Platform%基于Linux平台的单元测试用例执行框架

    Institute of Scientific and Technical Information of China (English)

    金凯峰; 王雅文

    2013-01-01

    Test case execution framework is part of CTS(Code Testing System).It is used to execute the test cases and capture instrument result. When CTS transplants from Windows platform to Linux platform,the test case execution framework encountered some problems, like thread system calls is not compatible to Linux Platform, exception capture failed and the source code of framework compiled failure. Pthread was used to make thread system calls available, and a exception stack was designed to solve exception capture problem, and the makeifle is parsed to extract head include ifles and lib options so that we can compile the source code successfully. The test case execution framework can run in Linux Platform.%测试用例执行框架是代码测试系统(Code Testing System CTS)的重要组成部分,用于执行测试用例,捕获插装结果。在CTS系统从Windows平台向Linux平台移植的过程中,测试用例执行框架遇到了线程调用和控制不兼容,异常捕获失败以及代码编译不通过等问题。本文通过使用Linux平台上常用的Pthread线程库,解决线程调用问题,通过设计并实现异常栈解决C语言异常捕获失败的问题,通过解析被测单元所在C语言工程的makeifle文件,提取出编译需要的头文件及链接共享库或静态链接库需要的链接选项,解决测试用例执行框架编译失败的问题。通过解决上述问题,CTS的测试用例执行框架能够在Linux平台上正常运行。

  8. RCP induces Slug expression and cancer cell invasion by stabilizing β1 integrin.

    Science.gov (United States)

    Hwang, M H; Cho, K H; Jeong, K J; Park, Y-Y; Kim, J M; Yu, S-L; Park, C G; Mills, G B; Lee, H Y

    2017-02-23

    Rab coupling protein (RCP)-induced tumor cell migration has been implicated in tumor pathophysiology and patient outcomes. In the present study, we demonstrate that RCP stabilizes β1 integrin leading to increased β1 integrin levels and activation of a signaling cascade culminating in Slug induction, epithelial-to-mesenchymal transition and increased invasion. Ectopic expression of RCP induced Slug expression. Silencing β1 integrin efficiently inhibited RCP-induced Slug expression and subsequent cancer cell invasion. Conversely, ectopic expression of β1 integrin was sufficient to induce Slug expression. Pharmacological inhibition of integrin linked kinase (ILK), EGFR and NF-κB, as well as transfection of a dominant-negative mutant of Ras (RasN17), significantly inhibited RCP-induced Slug expression and cancer cell invasion. Strikingly, ectopic expression of RCP was sufficient to enhance metastasis of ovarian cancer cells to the lung. Collectively, we demonstrate a mechanism by which RCP promotes cancer cell aggressiveness through sequential β1 integrin stabilization, activation of an ILK/EGFR/Ras/NF-κB signaling cascade and subsequent Slug expression.

  9. Prospects of riboflavin carrier protein (RCP) as an antifertility vaccine in male and female mammals.

    Science.gov (United States)

    Adiga, P R; Subramanian, S; Rao, J; Kumar, M

    1997-01-01

    Riboflavin carrier protein (RCP) is obligatorily involved in yolk deposition of the vitamin, riboflavin, in the developing oocyte of the hen. The production of this protein is inducible by oestrogen. It is evolutionarily conserved in terms of its physicochemical, immunological and functional characteristics. It is the prime mediator of vitamin supply to the developing fetus in mammals, including primates. Passive immunoneutralization of the protein terminates pregnancy in rats. Active immunization of rats and bonnet monkeys with avian RCP prevents pregnancy without causing any adverse physiological effects of the mother in terms of her vitamin status, reproductive cycles or reproductive-endocrine profile. Denatured, linearized RCP is more effective in eliciting neutralizing antibodies capable of interfering with embryonic viability either before or during peri-implantation stages. Two defined stretches of sequential epitopes, one located at the N-terminus and the other at the C-terminus of the protein have been identified. Active immunization with either of these epitopes conjugated with diphtheria toxoid curtails pregnancy in rats and monkeys. Immunohistochemical localization of RCP on ovulated oocytes and early embryos shows that the antibodies cause degeneration only of early embryos. RCP is produced intra-testicularly and becomes localized on acrosomal surface of mammalian spermatozoa. Active immunization of male rats and monkeys with denatured RCP markedly reduces fertility by impairing the fertilizing potential of spermatozoa. These findings suggest that RCP, or its defined fragments, could be a novel, first generation vaccine for regulating fertility in both the sexes.

  10. A new fluorescent imaging of renal inflammation with RCP.

    Science.gov (United States)

    Nakamura, Kentaro; Tabata, Yasuhiko

    2010-12-20

    The objective of this study is to design a fluorescent imaging agent with R-Gel, one of the recombinant polymers (RCP), for renal inflammation. The R-Gel based on human type I collagen has multiple Arg-Gly-Asp (RGD) motifs which are ligands for some types of integrin receptors on the cell surface. After intravenous administration of R-Gel labeled by Cy7 of a fluorescent dye to three animal models of nephritis mousse, interstitial nephritis (by using UUO model mice), glomerulonephritis (HIGA mice), and ischemia-reperfusion injured kidney (I/R mice), the extent of fluorescent imaging at the renal inflammation was assessed. The Cy7-labeled R-Gel was accumulated in the inflammation site to a significantly greater extent than in the normal one at 24h after administration. The renal pattern of fluorescent imaging was similar to that of administration anti-Mac1 antibody. Taken together, it is conceivable that the R-Gel was targeted to macrophages infiltrated into the inflammation site of kidney. Copyright © 2010 Elsevier B.V. All rights reserved.

  11. Optimization Design of Topological Structure on Interconnection Networks——RCP(n)%互联网络RCP(n)的拓扑结构优化设计

    Institute of Scientific and Technical Information of China (English)

    刘三满

    2008-01-01

    提出一种新的互联网络拓扑结构--基于交叉立方体环连接的Petersen图互联网络RCP(n).研究互联网络RCP(n)的通信特性.通过RCP(n)的单播路由算法、广播路由算法、可分组性算法,证明RCP(n)不仅具有环、彼特森图和交叉立方体本身所具有的性质,同时又具有自身独特的拓扑性质.研究结果表明,RCP(n)是一种具有良好拓扑结构和通信特性的互联网络.在通信效率上的花费只有由超立方体构成的互联网络的1/2,而通信效率却是由超立方体构成的互联网络的一倍.

  12. Study on Framework of Urban Logistics Public Information Platform System%城市物流公共信息平台系统框架研究

    Institute of Scientific and Technical Information of China (English)

    王进富; 张颖颖; 张永合

    2012-01-01

    促进物流公共信息平台建设是推动我国物流信息化快速发展的关键所在.以深圳物流业及物流信息化发展为例,总结了其发展现状,提出了城市物流公共信息平台的定位及子系统,构建了基于SOA-BPM架构的深圳物流公共信息平台结构框架,进而提出了平台建设的对策与建议.%In this paper, in the case of the logistics industry and the lopslir s informalization of Shenzhen, we proposed the positioning of the urban logistics public information platform and its subsystems, constructed the framework of the logistics public information platform of Shenzhen based on SO A—BPM and then proposed theeountermeasures and suggestions for the construction of the platform.

  13. On demand: The singular rht net, an ideal blueprint for the construction of a metal-organic framework (mof) platform

    KAUST Repository

    Eubank, Jarrod F.

    2012-09-07

    The exceptional nature of the rht-MOF platform, based on a singular edge-transitive net (the only net for the combination of 3- and 24-connected nodes), makes it an ideal target in crystal chemistry. The high level of control indicates an unparalleled blueprint for isoreticular functional materials (without concern for interpenetration) for targeted applications. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  14. Is Rab25 a tumor promoter or suppressor--context dependency on RCP status?

    Science.gov (United States)

    Tang, Bor Luen

    2010-08-01

    Conflicting reports in the literature suggest that Rab25 could either be a context dependent promoter or suppressor of tumorigenesis. We hypothesized that whether Rab25 acts as a promoter or suppressor in tumor progression depends on the expression status of its effector, the Rab coupling protein (RCP). An elevated expression of RCP resulting from genomic amplification may enhance Rab25's tumor progression activity. Elevation of Rab25 alone may sequester endogenous RCP, and attenuates its activating effect on other oncogenic products, such as mutant Ras.

  15. Guías clinicas de RCP y SRI enfermería

    OpenAIRE

    Donis Mulero, Elena

    2015-01-01

    La reanimación cardiopulmonar (RCP) es un procedimiento de emergencia para salvar vidas que se lleva a cabo cuando una persona se encuentra en parada cardiorrespiratoria (PCR). Tanto la técnica de RCP como la de intubación, son aspectos olvidados por los profesionales de la salud. Recopilar las últimas recomendaciones sobre RCP para poder elaborar un programa sencillo enfocado a la enfermería. Elaborar una guía sencilla de secuencia rápida de intubación (SRI). Revisión bibliográfica en la que...

  16. 互联网络RCP(n)的组播路由算法

    Institute of Scientific and Technical Information of China (English)

    刘宏英; 高太平

    2007-01-01

    互联网络RCP(Ringed Crossed cube Petersen)拓扑结构被提出后并没有给出组播算法.本文利用RCP(n)网络的正则性、良好的可扩展性,以及比Qn,HP(n),RHP(n)网络直径更短和构造开销更小这些特性,按照构造组播树的方法,给出了RCP(n)网络的组播路由算法,并对该算法作了性能分析.

  17. OpenVX-based Python Framework for real-time cross platform acceleration of embedded computer vision applications

    Directory of Open Access Journals (Sweden)

    Ori Heimlich

    2016-11-01

    Full Text Available Embedded real-time vision applications are being rapidly deployed in a large realm of consumer electronics, ranging from automotive safety to surveillance systems. However, the relatively limited computational power of embedded platforms is considered as a bottleneck for many vision applications, necessitating optimization. OpenVX is a standardized interface, released in late 2014, in an attempt to provide both system and kernel level optimization to vision applications. With OpenVX, Vision processing are modeled with coarse-grained data flow graphs, which can be optimized and accelerated by the platform implementer. Current full implementations of OpenVX are given in the programming language C, which does not support advanced programming paradigms such as object-oriented, imperative and functional programming, nor does it have runtime or type-checking. Here we present a python-based full Implementation of OpenVX, which eliminates much of the discrepancies between the object-oriented paradigm used by many modern applications and the native C implementations. Our open-source implementation can be used for rapid development of OpenVX applications in embedded platforms. Demonstration includes static and real-time image acquisition and processing using a Raspberry Pi and a GoPro camera. Code is given as supplementary information. Code project and linked deployable virtual machine are located on GitHub: https://github.com/NBEL-lab/PythonOpenVX.

  18. 基于跨平台的移动应用开发框架研究%Research on Mobile Application Development Framework Based on Cross Platform

    Institute of Scientific and Technical Information of China (English)

    苏玉慧

    2015-01-01

    With the rapid development of China’s economy and improvement of science and technology,the rapid popularization of mobile terminals such as smart phones,tablet PCs gradually change people’s way of life. At the same time,the mobile operating platform is in a gradual development,so that mobile applications are springing up like mushrooms.At present,the contradiction between mobile operating platform and application is becoming more and more prominent,which has higher requirements for cross platform mobile applications.Therefore,this paper mainly discusses the development framework of cross platform mobile application development.%随着我国经济的快速发展和科学技术水平的提高,智能手机、平板电脑等移动终端迅速普及,逐渐改变着人们的生活方式。与此同时,移动操作平台处于逐渐发展中,使移动应用程序如雨后春笋般不断涌现。目前,移动操作平台与应用程序的矛盾日益突出,对跨平台的移动应用有着更高的要求。因此,文章主要针对跨平台移动应用开发框架进行了论述。

  19. Analysing the climatic extremes of future projections for the MedCORDEX domain using RCP4.5 and RCP8.5 scenario

    Science.gov (United States)

    Bartholy, Judit; Pongracz, Rita; Pieczka, Ildiko; Szabone Andre, Karolina

    2017-04-01

    In this study HadGEM2 global climate model outputs were downscaled with RegCM4.3 for the entire MED-44 CORDEX area for the period 1950-2099 using RCP4.5 and RCP8.5 scenario. The 50-km resolution RegCM-outputs served as input for further downscaling using 10 km as a horizontal resolution for a smaller domain covering Central Europe with special focus on the Carpathian Region. RCP4.5 is a stabilization scenario while RCP8.5 is a rising radiative forcing pathway, therefore, the difference in the simulation outputs helps to quantify the inertia of the climate system, the importance of anthropogenic influence on climate, and shows the evidence for the need of mitigation and adaptation measures. Evidently, higher temperature change corresponds to RCP8.5 compared to RCP4.5. The difference of global and/or regional warming between the two scenario can reach (or even exceed) 2 °C from the second part of the century. Differences in precipitation projections are less straightforward to explain as no direct link exists with warming and radiative forcing, however, the annual distribution of precipitation is projected to change, which may lead to important consequences on society. Our analysis compares the estimated temperature and precipitation changes with special focus on extreme climatic conditions for the following 10 subregions of the MED-44 CORDEX area: Iberian Peninsula, Apennine Peninsula, Balkan Region, Asia Minor, East European Plain, Middle European Plain, Carpathian Basin, Carpathian Mountains, Alps, Western Europe.

  20. Metal organic framework absorbent platforms for removal of co2 and h2s from natural gas

    KAUST Repository

    Belmabkhout, Youssef

    2016-10-13

    Provided herein are metal organic frameworks comprising metal nodes and N-donor organic ligands which have high selectivity and stability in the present of gases and vapors including H2S, H2O, and CO2. Methods include capturing one or more of H2S, H2O, and CO2 from fluid compositions, such as natural gas.

  1. From Print to Digital Platforms: A PBL Framework for Fostering Multimedia Competencies and Consciousness in Traditional Journalism Education

    Science.gov (United States)

    Goh, Debbie; Kale, Ugur

    2015-01-01

    The project-based learning (PBL) approach closely reflects the tenets of journalism and provides a potential pedagogical guide for transforming traditional journalism education. This study operationalizes and applies a PBL framework in digitizing a print journalism course. The findings illustrate how the presence of seven key elements of PBL…

  2. Diacylglycerol kinase α controls RCP-dependent integrin trafficking to promote invasive migration.

    Science.gov (United States)

    Rainero, Elena; Caswell, Patrick T; Muller, Patricia A J; Grindlay, Joan; McCaffrey, Mary W; Zhang, Qifeng; Wakelam, Michael J O; Vousden, Karen H; Graziani, Andrea; Norman, Jim C

    2012-01-23

    Inhibition of αvβ3 integrin or expression of oncogenic mutants of p53 promote invasive cell migration by enhancing endosomal recycling of α5β1 integrin under control of the Rab11 effector Rab-coupling protein (RCP). In this paper, we show that diacylglycerol kinase α (DGK-α), which phosphorylates diacylglycerol to phosphatidic acid (PA), was required for RCP to be mobilized to and tethered at the tips of invasive pseudopods and to allow RCP-dependent α5β1 recycling and the resulting invasiveness of tumor cells. Expression of a constitutive-active mutant of DGK-α drove RCP-dependent invasion in the absence of mutant p53 expression or αvβ3 inhibition, and conversely, an RCP mutant lacking the PA-binding C2 domain was not capable of being tethered at pseudopod tips. These data demonstrate that generation of PA downstream of DGK-α is essential to connect expression of mutant p53s or inhibition of αvβ3 to RCP and for this Rab11 effector to drive the trafficking of α5β1 that is required for tumor cell invasion through three-dimensional matrices.

  3. NIR-Selective electrochromic heteromaterial frameworks: a platform to understand mesoscale transport phenomena in solid-state electrochemical devices

    Energy Technology Data Exchange (ETDEWEB)

    Williams, TE; Chang, CM; Rosen, EL; Garcia, G; Runnerstrom, EL; Williams, BL; Koo, B; Buonsanti, R; Milliron, DJ; Helms, BA

    2014-01-01

    We report here the first solid-state, NIR-selective electrochromic devices. Critical to device performance is the arrangement of nanocrystal-derived electrodes into heteromaterial frameworks, where hierarchically porous ITO nanocrystal active layers are infiltrated by an ion-conducting polymer electrolyte with mesoscale periodicity. Enhanced coloration efficiency and transport are realized over unarchitectured electrodes in devices, paving the way towards new smart windows technologies.

  4. Metaliteracy as Pedagogical Framework for Learner-Centered Design in Three MOOC Platforms: Connectivist, Coursera and Canvas

    Directory of Open Access Journals (Sweden)

    Kelsey L. O'Brien

    2017-09-01

    Full Text Available This article examines metaliteracy as a pedagogical model that leverages the assets of MOOC platforms to enhance self-regulated and self-empowered learning. Between 2013 and 2015, a collaborative teaching team within the State University of New York (SUNY developed three MOOCs on three different platforms—connectivist, Coursera and Canvas—to engage with learners about metaliteracy. As a reframing of information literacy, metaliteracy envisions the learner as an active and metacognitive producer of digital information in online communities and social media environments (Mackey & Jacobson, 2011; 2014. This team of educators, which constitutes the core of the Metaliteracy Learning Collaborative, used metaliteracy as a lens for applied teaching and learning strategies in the development of a cMOOC and two xMOOCs. The metaliteracy MOOCs pushed against the dominant trends of lecture-based, automated MOOC design towards a more learner-centered pedagogy that aligns with key components of metaliteracy.

  5. Shortest path algorithm of RCP(n) networks%互联网络RCP(n)的最短路算法

    Institute of Scientific and Technical Information of China (English)

    王敏; 高太平; 刘宏英; 闫宇琦

    2009-01-01

    RCP(n)是最近提出的一种新型互联网络拓扑结构,是由环、Petersen图和交叉立方体所组成的,具有短直径、良好的可扩展性和正则性以及较小的构造开销的性质,是一种具有良好拓扑性质的互联网络.针对RCP(n)上节点编码的特点,采用逐步分解编码,依次寻找路径的方法给出了寻找RCP(n)上任意两点间最短路的一个多项式算法,为RCP(n)上作进一步的路由算法、最优分组等通讯性能的研究提供了理论支持,因此具有一定的理论意义和应用价值.

  6. 开放式多参数校准平台架构及实践%The Framework and Implementation of Open Multi-parameter Calibration Platform

    Institute of Scientific and Technical Information of China (English)

    王凯让; 王永杰; 苏东林; 邵华

    2014-01-01

    The topic states the conception of synthesis calibration based on advanced test bus, using the design of modular, standard, open, systemic framework, researching the technique of portable, open multi-parameter calibration platform, supporting metrology and calibration of the field test devices greatly.%应用模块化、标准化的开放式系统结构的设计思路,提出基于先进的测试总线的综合校准概念,研究便携高效、可扩展性强的开放式多参数校准平台构架技术,有力支撑了现场测试设备的计量校准工作。

  7. Platform Constellations

    DEFF Research Database (Denmark)

    Staykova, Kalina Stefanova; Damsgaard, Jan

    2016-01-01

    messaging apps KakaoTalk and LINE, we are able to gain valuable insights about the nature of these new constructions and to capture and synthesize their main characteristics in a framework. Our results show that platform constellations possess unique innovative capabilities, which can improve users......’ acquisition and users’ engagement rates as well as unlock new sources of value creation and diversify revenue streams....

  8. Metal-Organic Framework Thin Films as Platforms for Atomic Layer Deposition of Cobalt Ions To Enable Electrocatalytic Water Oxidation.

    Science.gov (United States)

    Kung, Chung-Wei; Mondloch, Joseph E; Wang, Timothy C; Bury, Wojciech; Hoffeditz, William; Klahr, Benjamin M; Klet, Rachel C; Pellin, Michael J; Farha, Omar K; Hupp, Joseph T

    2015-12-30

    Thin films of the metal-organic framework (MOF) NU-1000 were grown on conducting glass substrates. The films uniformly cover the conducting glass substrates and are composed of free-standing sub-micrometer rods. Subsequently, atomic layer deposition (ALD) was utilized to deposit Co(2+) ions throughout the entire MOF film via self-limiting surface-mediated reaction chemistry. The Co ions bind at aqua and hydroxo sites lining the channels of NU-1000, resulting in three-dimensional arrays of separated Co ions in the MOF thin film. The Co-modified MOF thin films demonstrate promising electrocatalytic activity for water oxidation.

  9. Measuring Progress on the Control of Porcine Reproductive and Respiratory Syndrome (PRRS) at a Regional Level: The Minnesota N212 Regional Control Project (Rcp) as a Working Example.

    Science.gov (United States)

    Valdes-Donoso, Pablo; Jarvis, Lovell S; Wright, Dave; Alvarez, Julio; Perez, Andres M

    2016-01-01

    Due to the highly transmissible nature of porcine reproductive and respiratory syndrome (PRRS), implementation of regional programs to control the disease may be critical. Because PRRS is not reported in the US, numerous voluntary regional control projects (RCPs) have been established. However, the effect of RCPs on PRRS control has not been assessed yet. This study aims to quantify the extent to which RCPs contribute to PRRS control by proposing a methodological framework to evaluate the progress of RCPs. Information collected between July 2012 and June 2015 from the Minnesota Voluntary Regional PRRS Elimination Project (RCP-N212) was used. Demography of premises (e.g. composition of farms with sows = SS and without sows = NSS) was assessed by a repeated analysis of variance. By using general linear mixed-effects models, active participation of farms enrolled in the RCP-N212, defined as the decision to share (or not to share) PRRS status, was evaluated and used as a predictor, along with other variables, to assess the PRRS trend over time. Additionally, spatial and temporal patterns of farmers' participation and the disease dynamics were investigated. The number of farms enrolled in RCP-N212 and its geographical coverage increased, but the proportion of SS and NSS did not vary significantly over time. A significant increasing (pRCP-N212, active participation is not ensured. By evaluating the effect of participation on the occurrence of PRRS, the value of sharing information among producers may be demonstrated, in turn justifying the existence of RCPs.

  10. Characterization and localization of the rabbit ocular calcitonin gene-related peptide (CGRP)-receptor component protein (RCP).

    Science.gov (United States)

    Rosenblatt, M I; Dahl, G P; Dickerson, I M

    2000-04-01

    To determine whether the calcitonin gene-related peptide (CGRP) receptor component protein (RCP), a novel signal transduction molecule, is required for CGRP signaling in the eye and to determine potential ocular sites of CGRP action. The cDNA for the rabbit ocular RCP homologue was cloned using a combination of reverse transcription-polymerase chain reaction (RT-PCR) and rapid amplification of cDNA ends (RACE). Function of the rabbit ocular RCP was assessed using a sensitive oocyte-based assay, which utilizes the protein kinase A (PKA)-sensitive cystic fibrosis transmembrane conductance regulator (CFTR) as a sensor of cAMP formation. RCP expression in the rabbit eye was localized using immunohistochemistry. A 2063-bp cDNA for the rabbit ocular RCP was cloned and sequenced. Expression of the rabbit RCP cDNA confers CGRP responsiveness in a sensitive oocyte-based assay. Antisense oligonucleotides made to the ocular RCP abolishes CGRP responsiveness of ciliary body and iris mRNA in the oocyte-CFTR assay. Localization of RCP protein in the rabbit eye using immunohistochemistry demonstrated RCP immunoreactivity in the ciliary body and iris blood vessels, as well as in layers of the ciliary epithelium. The rabbit ocular RCP appears to be required for signal transduction at ocular CGRP receptors and is localized to sites previously reported to bind CGRP, which affect intraocular pressure and neurogenic inflammation.

  11. Research on selection framework of enterprise PaaS platform products%企业PaaS平台产品选择框架研究

    Institute of Scientific and Technical Information of China (English)

    周毅书; 周剑雄; 徐星; 殷星

    2015-01-01

    The three-layer service architecture(SaaS, PaaS and IaaS)of computing has a deep impact on the enterprise information system construction. Among them, the selection of Platform as a Service(PaaS)products, which is not solved by a perfect solution, has become a thorny issue in the construction of the enterprise private cloud. Therefore, a framework of enterprise PaaS platform product selection is proposed. This paper respectively studies the enterprise service oriented architecture integrated with cloud computing pattern, the construction method of PaaS products measuring metrics and multi-attribute products selection decision-making process based on ANP from three aspects of PaaS product selection, namely requirement analysis, measuring indexes and selection method. This paper shows the effect of the framework on improving the decision-making ability of enterprise PaaS platform products selection by a case.%云计算的三层服务架构(SaaS、PaaS、IaaS)正深刻地影响着企业信息化系统建设,其中平台即服务(PaaS)产品选择问题成为当前企业私有云构建中的棘手问题,至今仍无好的解决方法。为此,提出一个企业PaaS平台产品选择框架,分别从PaaS产品选择的需求分析、测评指标和评选方法三方面研究融合云计算模式的企业面向服务体系架构,PaaS产品评价指标体系的构建方法和基于ANP的多属性产品选择决策过程。通过一个案例展示该选择框架在提高企业PaaS平台产品选择决策水平中的作用。

  12. Sensitivity Analysis on LOCCW of Westinghouse typed Reactors Considering WOG2000 RCP Seal Leakage Model

    Energy Technology Data Exchange (ETDEWEB)

    Na, Jang-Hwan; Jeon, Ho-Jun; Hwang, Seok-Won [KHNP Central Research Institute, Daejeon (Korea, Republic of)

    2015-10-15

    In this paper, we focus on risk insights of Westinghouse typed reactors. We identified that Reactor Coolant Pump (RCP) seal integrity is the most important contributor to Core Damage Frequency (CDF). As we reflected the latest technical report; WCAP-15603(Rev. 1-A), 'WOG2000 RCP Seal Leakage Model for Westinghouse PWRs' instead of the old version, RCP seal integrity became more important to Westinghouse typed reactors. After Fukushima accidents, Korea Hydro and Nuclear Power (KHNP) decided to develop Low Power and Shutdown (LPSD) Probabilistic Safety Assessment (PSA) models and upgrade full power PSA models of all operating Nuclear Power Plants (NPPs). As for upgrading full power PSA models, we have tried to standardize the methodology of CCF (Common Cause Failure) and HRA (Human Reliability Analysis), which are the most influential factors to risk measures of NPPs. Also, we have reviewed and reflected the latest operating experiences, reliability data sources and technical methods to improve the quality of PSA models. KHNP has operating various types of reactors; Optimized Pressurized Reactor (OPR) 1000, CANDU, Framatome and Westinghouse. So, one of the most challengeable missions is to keep the balance of risk contributors of all types of reactors. This paper presents the method of new RCP seal leakage model and the sensitivity analysis results from applying the detailed method to PSA models of Westinghouse typed reference reactors. To perform the sensitivity analysis on LOCCW of the reference Westinghouse typed reactors, we reviewed WOG2000 RCP seal leakage model and developed the detailed event tree of LOCCW considering all scenarios of RCP seal failures. Also, we performed HRA based on the T/H analysis by using the leakage rates for each scenario. We could recognize that HRA was the sensitive contributor to CDF, and the RCP seal failure scenario of 182gpm leakage rate was estimated as the most important scenario.

  13. RCP 技术在 Eclipse 与 NetBeans 上的分析比较

    Institute of Scientific and Technical Information of China (English)

    王锋

    2008-01-01

    RCP(Rich Client Platform)技术是通过定义微内核和相应的扩展机制,实现了基础表现层与业务层的近乎完全隔离,有效的改善了软件开发中的模块紧耦合,进一步提高了软件的可维护性、可复用性和可扩展性.但是目前富客户技术尚处于发展时期,在技术和实践方面还存在很多局限性,主要有微内核实现协议不够通用、插件机制各有不同、界面开发不能兼容等亟待解决的问题.本文以此为背景,研究分析了现有的几种富客户开发方法,并重点分析比较了其中的Eclipse RCP和NetBeans RCP,探索它们之间的异构性和相似性,深入研究了它们的体系结构和特点.分析表明,借助于新的技术和模式,目前对富客户开发技术的研究进展,为各领域软件构造提供了强有力的支持.

  14. Highly stable aluminum-based metal-organic frameworks as biosensing platforms for assessment of food safety.

    Science.gov (United States)

    Liu, Chun-Sen; Sun, Chun-Xiao; Tian, Jia-Yue; Wang, Zhuo-Wei; Ji, Hong-Fei; Song, Ying-Pan; Zhang, Shuai; Zhang, Zhi-Hong; He, Ling-Hao; Du, Miao

    2017-05-15

    Two unique immunosensors made of aluminum-based metal-organic frameworks (MOFs), namely, 515- and 516-MOFs, with 4,4',4''-nitrilotribenzoic acid (H3NTB) were successfully obtained to efficiently assess food safety. The as-prepared 515- and 516-MOFs exhibited superior thermal and physicochemical stability, high electrochemical activity, and good biocompatibility. Among these immunosensors, 516-MOF showed a preferable biosensing ability toward analytes determined by electrochemical techniques. The developed 516-MOF-based electrochemical biosensor not only demonstrated high sensitivity with low detection limits of 0.70 and 0.40pgmL(-1) toward vomitoxin and salbutamol, respectively, but also showed good selectivity in the presence of other interferences. Therefore, with the advantages of high sensitivity, good selectivity, and simple operation, this new strategy is believed to exhibit great potential for simple and convenient detection of poisonous and harmful residues in food.

  15. Alginate Hydrogel: A Shapeable and Versatile Platform for in Situ Preparation of Metal-Organic Framework-Polymer Composites.

    Science.gov (United States)

    Zhu, He; Zhang, Qi; Zhu, Shiping

    2016-07-13

    This work reports a novel in situ growth approach for incorporating metal-organic framework (MOF) materials into an alginate substrate, which overcomes the challenges of processing MOF particles into specially shaped structures for real industrial applications. The MOF-alginate composites are prepared through the post-treatment of a metal ion cross-linked alginate hydrogel with a MOF ligand solution. MOF particles are well distributed and embedded in and on the surface of the composites. The macroscopic shape of the composite can be designed by controlling the shape of the corresponding hydrogel; thus MOF-alginate beads, fibers, and membranes are obtained. In addition, four different MOF-alginate composites, including HKUST-1-, ZIF-8-, MIL-100(Fe)-, and ZIF-67-alginate, were successfully prepared using different metal ion cross-linked alginate hydrogels. The mechanism of formation is revealed, and the composite is demonstrated to be an effective absorbent for water purification.

  16. An Ultrahydrophobic Fluorous Metal-Organic Framework Derived Recyclable Composite as a Promising Platform to Tackle Marine Oil Spills.

    Science.gov (United States)

    Mukherjee, Soumya; Kansara, Ankit M; Saha, Debasis; Gonnade, Rajesh; Mullangi, Dinesh; Manna, Biplab; Desai, Aamod V; Thorat, Shridhar H; Singh, Puyam S; Mukherjee, Arnab; Ghosh, Sujit K

    2016-07-25

    Derived from a strategically chosen hexafluorinated dicarboxylate linker aimed at the designed synthesis of a superhydrophobic metal-organic framework (MOF), the fluorine-rich nanospace of a water-stable MOF (UHMOF-100) exhibits excellent water-repellent features. It registered the highest water contact angle (≈176°) in the MOF domain, marking the first example of an ultrahydrophobic MOF. Various experimental and theoretical studies reinforce its distinctive water-repellent characteristics, and the conjugation of superoleophilicity and unparalleled hydrophobicity of a MOF material has been coherently exploited to achieve real-time oil/water separation in recyclable membrane form, with significant absorption capacity performance. This is also the first report of an oil/water separating fluorinated ultrahydrophobic MOF-based membrane material, with potential promise for tackling marine oil spillages.

  17. RCP is a human breast cancer-promoting gene with Ras-activating function.

    Science.gov (United States)

    Zhang, Jinqiu; Liu, Xuejing; Datta, Arpita; Govindarajan, Kunde; Tam, Wai Leong; Han, Jianyong; George, Joshy; Wong, Christopher; Ramnarayanan, Kalpana; Phua, Tze Yoong; Leong, Wan Yee; Chan, Yang Sun; Palanisamy, Nallasivam; Liu, Edison Tak-Bun; Karuturi, Krishna Murthy; Lim, Bing; Miller, Lance David

    2009-08-01

    Aggressive forms of cancer are often defined by recurrent chromosomal alterations, yet in most cases, the causal or contributing genetic components remain poorly understood. Here, we utilized microarray informatics to identify candidate oncogenes potentially contributing to aggressive breast cancer behavior. We identified the Rab-coupling protein RCP (also known as RAB11FIP1), which is located at a chromosomal region frequently amplified in breast cancer (8p11-12) as a potential candidate. Overexpression of RCP in MCF10A normal human mammary epithelial cells resulted in acquisition of tumorigenic properties such as loss of contact inhibition, growth-factor independence, and anchorage-independent growth. Conversely, knockdown of RCP in human breast cancer cell lines inhibited colony formation, invasion, and migration in vitro and markedly reduced tumor formation and metastasis in mouse xenograft models. Overexpression of RCP enhanced ERK phosphorylation and increased Ras activation in vitro. As these results indicate that RCP is a multifunctional gene frequently amplified in breast cancer that encodes a protein with Ras-activating function, we suggest it has potential importance as a therapeutic target. Furthermore, these studies provide new insight into the emerging role of the Rab family of small G proteins and their interacting partners in carcinogenesis.

  18. RCP is a human breast cancer–promoting gene with Ras-activating function

    Science.gov (United States)

    Zhang, Jinqiu; Liu, Xuejing; Datta, Arpita; Govindarajan, Kunde; Tam, Wai Leong; Han, Jianyong; George, Joshy; Wong, Christopher; Ramnarayanan, Kalpana; Phua, Tze Yoong; Leong, Wan Yee; Chan, Yang Sun; Palanisamy, Nallasivam; Liu, Edison Tak-Bun; Karuturi, Krishna Murthy; Lim, Bing; Miller, Lance David

    2009-01-01

    Aggressive forms of cancer are often defined by recurrent chromosomal alterations, yet in most cases, the causal or contributing genetic components remain poorly understood. Here, we utilized microarray informatics to identify candidate oncogenes potentially contributing to aggressive breast cancer behavior. We identified the Rab-coupling protein RCP (also known as RAB11FIP1), which is located at a chromosomal region frequently amplified in breast cancer (8p11–12) as a potential candidate. Overexpression of RCP in MCF10A normal human mammary epithelial cells resulted in acquisition of tumorigenic properties such as loss of contact inhibition, growth-factor independence, and anchorage-independent growth. Conversely, knockdown of RCP in human breast cancer cell lines inhibited colony formation, invasion, and migration in vitro and markedly reduced tumor formation and metastasis in mouse xenograft models. Overexpression of RCP enhanced ERK phosphorylation and increased Ras activation in vitro. As these results indicate that RCP is a multifunctional gene frequently amplified in breast cancer that encodes a protein with Ras-activating function, we suggest it has potential importance as a therapeutic target. Furthermore, these studies provide new insight into the emerging role of the Rab family of small G proteins and their interacting partners in carcinogenesis. PMID:19620787

  19. Domestic activity for technical development of the APR1400's RCP performance test

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Seok; Kim, Seok; Bae, Byung-Uhn; Cho, Yun-Jae; Kim, Yeon-Sik; Jeon, Woo-Jin; Yun, Young-Jung [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-10-15

    The thermal hydraulic and electric capability of the RCP test facility (RCPTF) covers up to 18.5 MPa, 343 .deg. C, 11.7 m{sup 3}/s, and 14.0 MW in the design pressure, temperature, flow rate, and the maximum electric power, respectively. In 2013, commissioning test had been performed to verify its designed capability, followed by several modifications in the RCPTF including signal processing and control logic to enhance verification and evaluation capability of the RCP performance. After finishing the commissioning and modification of the RCPTF, type test for the new-type RCP had been performed successfully. In this paper, several technical issues developed in the 2013 and the type test's method and results will be described. In the present paper, the technical activities for the development of the verification test of APR1400's RCP are described. KAERI has completed the full set of technology development, prerequisite for the RCP verification test, and now on the way to perform a test for the sealing capacity of the seal assembly during the Station Block Out (SBO) condition of APR1400.

  20. Two-Dimensional Imine-Linked Covalent Organic Frameworks as a Platform for Selective Oxidation of Olefins.

    Science.gov (United States)

    Mu, Manman; Wang, Yanwen; Qin, Yutian; Yan, Xilong; Li, Yang; Chen, Ligong

    2017-07-12

    Two-dimensional imine-linked covalent organic frameworks with hydroxyl groups, TAPT-DHTA-COFHX and TAPT-DHTA-COFDMF, were respectively constructed by the condensation of 1,3,5-tris-(4-aminophenyl)triazine and 2,5-dihydroxyl-terephthalaldehyde under solvothermal and reflux conditions. Both COFs possess excellent thermal stability and a similar eclipsed stacking structure verified by XRD patterns. However, TAPT-DHTA-COFHX presented a larger surface area (2238 m(2)/g) and higher crystallinity than TAPT-DHTA-COFDMF. Significantly, copper ions are efficiently incorporated into the pores of these two COFs via the coordination interaction with hydroxyl groups and imine linkers. The obtained copper-containing COFs (Cu-COFHX and Cu-COFDMF) were employed in the selective oxidation of styrene to benzaldehyde. Cu-COFHX with superior surface area (1886 m(2)/g) and pore volume (1.11 cm(3)/g) exhibited excellent catalytic performance and recyclability. This strategy not only provides a convenient approach to design imine-linked 2D COFs with hydroxyl groups, but also develops their novel application for catalysis.

  1. International educational partnerships for doctors in training: a collaborative framework with the RCP.

    Science.gov (United States)

    Thomson, George A; Foster, Matthew; Sheriff, Rezvi; Mendis, Lalitha; Fernando, Devaka J S; Blundell, Caroline; Worrall, Jeffrey; Black, Carol

    2005-01-01

    The UK offers excellent postgraduate medical education, and overseas doctors in training often covet a period of training in the UK. Some overseas training authorities make UK training mandatory prior to appointment as a consultant. Unfortunately, the organisation of such training often proves to be ad hoc, and may lack educational value. UK training faces challenges as a result of reduced hours of work, more structured and intensive educational needs, and pressures of increasing clinical demand. A plethora of new 'trust' posts have developed, often with limited educational value, creating a risk that training quality for overseas doctors is reduced. Against this background, such posts can be used to create international training partnerships such as that at Sherwood Forest Hospitals NHS Trust (SFHT), providing high-quality general and specialty training. Given the success of this strategy, it would be desirable for other UK trusts to provide similar schemes offering specialties not covered at SFHT.

  2. Implications of RCP emissions on future PM2.5 air quality and direct radiative forcing over China

    Science.gov (United States)

    Li, Ke; Liao, Hong; Zhu, Jia; Moch, Jonathan M.

    2016-11-01

    Severe PM2.5 air pollution in China and the First Grand National Standard (FGNS), implemented in 2016 (annual PM2.5 concentration target of less than 35 µg m-3), necessitate urgent reduction strategies. This study applied the nested-grid version of the Goddard Earth Observing System (GEOS) chemical transport model (GEOS-Chem) to quantify 2000-2050 changes in PM2.5 air quality and related direct radiative forcing (DRF) in China, based on future emission changes under the representative concentration pathway (RCP) scenarios of RCP2.6, RCP4.5, RCP6.0, and RCP8.5. In the near term (2000-2030), a projected maximum increase in PM2.5 concentrations of 10-15 µg m-3 is found over east China under RCP6.0 and RCP8.5 and less than 5 µg m-3 under RCP2.6 and RCP4.5. In the long term (2000-2050), PM2.5 pollution clearly improves, and the largest decrease in PM2.5 concentrations of 15-30 µg m-3 is over east China under all RCPs except RCP6.0. Focusing particularly on highly polluted regions, we find that Beijing-Tianjin-Hebei (BTH) wintertime PM2.5 concentrations meeting the FGNS occur after 2040 under RCP2.6, RCP4.5, and RCP8.5, and summertime PM2.5 concentrations reach this goal by 2030 under RCP2.6 and RCP4.5. In Sichuan Basin (SCB), wintertime PM2.5 concentrations below the FGNS occur only in 2050 under RCP2.6 and RCP4.5, although future summertime PM2.5 will be well controlled. The difficulty in controlling future PM2.5 concentrations relates to unmitigated high levels of nitrate, although NOx and SO2 emissions show substantial reductions during 2020-2040. The changes in aerosol concentrations lead to positive aerosol DRF over east China (20°-45°N, 100°-125°E) by 1.22, 1.88, and 0.66 W m-2 in 2050 relative to 2000 under RCP2.6, RCP4.5, and RCP8.5, respectively. When considering both health and climate effects of PM2.5 over China, for example, PM2.5 concentrations averaged over east China under RCP4.5 (RCP2.6) decrease by 54% (43%) in 2050 relative to 2000, but at the

  3. Metal–organic frameworks to satisfy gas upgrading demands: fine-tuning the soc-MOF platform for the operative removal of H2S

    KAUST Repository

    Belmabkhout, Youssef

    2017-01-06

    A cooperative experimental/modeling strategy was used to unveil the structure/gas separation performance relationship for a series of isostructural metal-organic frameworks (MOFs) with soc-topology (square-octahedral) hosting different extra-framework counter ions (NO3-, Cl- and Br-). In3+-, Fe3+-, Ga3+-and the newly isolated Al(III)-based isostructural soc-MOF were extensively studied and evaluated for the separation-based production of high-quality fuels (i.e., CH4, C3H8 and n-C4H10) and olefins. The structural/chemical fine-tuning of the soc-MOF platform promoted equilibrium-based selectivity toward C2+ (C2H6, C2H4, C3H6 C3H8 and n-C4H10) and conferred the desired chemical stability toward H2S. The noted dual chemical stability and gas/vapor selectivity, which have rarely been reported for equilibrium-based separation agents, are essential for the production of high-purity H-2, CH4 and C2+ fractions in high yields. Interestingly, the evaluated soc-MOF analogues exhibited high selectivity for C2H4, C3H6 and n-C4H10. In particular, the Fe, Ga and Al analogues presented relatively enhanced C2+/CH4 adsorption selectivities. Notably, the Ga and Al analogues were found to be technically preferable because their structural integrities and separation performances were maintained upon exposure to H2S, indicating that these materials are highly tolerant to H2S. Therefore, the Ga-soc-MOF was further examined for the selective adsorption of H2S in the presence of CO2-and CH4-containing streams, such as refinery-off gases (ROG) and natural gas (NG). Grand canonical Monte Carlo (GCMC) simulations based on a specific force field describing the interactions between the guest molecules and the Ga sites supported and confirmed the considerably higher affinity of the Ga-soc-MOF for C2+ (as exemplified by n-C4H10) than for CH4. The careful selection of an appropriate metal for the trinuclear inorganic molecular building block (MBB), i. e., a Ga metal center, imbues the soc

  4. [Assessment of cancer RCP meetings in Rhône-Alpes: a survey on the ground].

    Science.gov (United States)

    Descotes, J-L; Guillem, P; Bondil, P; Colombel, M; Chabloz, C

    2010-10-01

    The results of a local survey sent to urologists, oncologists and radiotherapeutists working in Rhône-Alpes have been reported to assess the value of multidisciplinary oncological meetings (RCP) in Urology. The results of this short study have been analyzed and compared to the national results published by the Inspection Générale des Affaires Sociales report. Meanwhile, we have created a professional electronic directory collecting all RCP of Rhône-Alpes, which will be accessible soon. Copyright © 2010. Published by Elsevier Masson SAS.

  5. Rab coupling protein (RCP): a novel target of progesterone action in primate endometrium.

    Science.gov (United States)

    Patil, V S; Sachdeva, G; Modi, D N; Katkam, R R; Manjramkar, D D; Hinduja, I; Puri, C P

    2005-10-01

    Acquisition of functional receptivity by the endometrium is assumed to be effected by progesterone-dependent expression and repression of several genes during the implantation window in a menstrual cycle. In the present study, we employed differential display (DD) reverse transcription-polymerase chain reaction (RT-PCR) to identify progesterone-dependent gene/gene fragments that are differentially expressed during the peri-implantation phase in receptive and nonreceptive endometria, obtained from fertile and infertile bonnet monkeys respectively. Receptive endometria were obtained from regularly cycling (n=5) fertile female bonnet monkeys. Endometrial nonreceptivity was induced by treating bonnet monkeys with either 2.5 mg (n=5) or 5.0 mg (n=5) onapristone (ZK 98.299), an antiprogestin, on every third day for one cycle. Ovulation, levels of circulatory hormones (estradiol and progesterone) and menstrual cycle length did not change in treated animals; however, endometrial growth was retarded. DD2, one of the differentially expressed cDNA fragments, showed higher representation in nonreceptive endometria than in receptive endometria. The DD2 sequence was found to be homologous to the sequence of the carboxyl terminal region of Rab coupling protein (RCP), a recently discovered protein involved in intracellular vesicular trafficking. To confirm the identity of DD2 as RCP, RT-PCR studies were carried out with a forward primer deduced from the RCP sequence and a reverse primer from the DD2 sequence. The product (DDRCP) obtained, when sequenced, revealed 95% homology with the nucleotide number 1196-1757 of human RCP cDNA. Furthermore, the pattern of DDRCP expression at transcript level was found to be similar to that shown by DD2; that is, it was higher in nonreceptive endometrium. Northern analysis using labeled DD2 or DDRCP cDNA fragments identified two transcripts of 6.0 and 4.0 kb in human endometrium. In situ hybridization studies using digoxigenin-labeled DD2

  6. Fe(III)-based metal-organic framework-derived core-shell nanostructure: Sensitive electrochemical platform for high trace determination of heavy metal ions.

    Science.gov (United States)

    Zhang, Zhihong; Ji, Hongfei; Song, Yingpan; Zhang, Shuai; Wang, Minghua; Jia, Changchang; Tian, Jia-Yue; He, Linghao; Zhang, Xiaojing; Liu, Chun-Sen

    2017-03-07

    A new core-shell nanostructured composite composed of Fe(III)-based metal-organic framework (Fe-MOF) and mesoporous Fe3O4@C nanocapsules (denoted as Fe-MOF@mFe3O4@mC) was synthesized and developed as a platform for determining trace heavy metal ions in aqueous solution. Herein, the mFe3O4@mC nanocapsules were prepared by calcining the hollow Fe3O4@C that was obtained using the SiO2 nanoparticles as the template, followed by composing the Fe-MOF. The Fe-MOF@mFe3O4@mC nanocomposite demonstrated excellent electrochemical activity, water stability and high specific surface area, consequently resulting in the strong biobinding with heavy-metal-ion-targeted aptamer strands. Furthermore, by combining the conformational transition interaction, which is caused by the formation of the G-quadruplex between a single-stranded aptamer and high adsorbed amounts of heavy metal ions, the developed aptasensor exhibited a good linear relationship with the logarithm of heavy metal ion (Pb(2+) and As(3+)) concentration over the broad range from 0.01 to 10.0nM. The detection limits were estimated to be 2.27 and 6.73 pM toward detecting Pb(2+) and As(3+), respectively. The proposed aptasensor showed good regenerability, excellent selectivity, and acceptable reproducibility, suggesting promising applications in environment monitoring and biomedical fields.

  7. Overexpression and Purification of Human Calcitonin Gene Related Peptide - Receptor Component Protein (CGRP-RCP) in Escherichia coli

    Science.gov (United States)

    Tolun, Adviye A.; Dickerson, Ian M.; Malhotra, Arun

    2007-01-01

    Calcitonin gene-related peptide (CGRP) is a neuropeptide secreted by the central and peripheral nervous system nerves that has important physiological functions such as vasodilation, cardiotonic actions, metabolic and pro-inflammatory effects. The CGRP receptor is unique among G-protein coupled receptors in that a functional CGRP receptor consists of at least three proteins: Calcitonin Like Receptor (CLR), Receptor Activity Modifying Protein (RAMP1) and Receptor Component Protein (RCP). RCP is a required factor in CGRP-mediated signal transduction and it couples the CGRP receptor to the signal transduction pathway. Here we describe methods to overexpress and purify RCP for structure-function studies. Human RCP was cloned and overexpressed with a poly-histidine tag and as a Maltose Binding Protein (MBP) fusion in Escherichia coli using commercially available expression vectors. While his-tagged RCP is prone to aggregation, solubility is improved when RCP is expressed as a MBP fusion. Expression and purification procedures for these constructs are described. Results from these studies will facilitate structural analysis of human RCP, and allow further understanding of RCP function. PMID:17067815

  8. Rab coupling protein (RCP), a novel Rab4 and Rab11 effector protein.

    Science.gov (United States)

    Lindsay, Andrew J; Hendrick, Alan G; Cantalupo, Giuseppina; Senic-Matuglia, Francesca; Goud, Bruno; Bucci, Cecilia; McCaffrey, Mary W

    2002-04-05

    Rab4 and Rab11 are small GTPases belonging to the Ras superfamily. They both function as regulators along the receptor recycling pathway. We have identified a novel 80-kDa protein that interacts specifically with the GTP-bound conformation of Rab4, and subsequent work has shown that it also interacts strongly with Rab11. We name this protein Rab coupling protein (RCP). RCP is predominantly membrane-bound and is expressed in all cell lines and tissues tested. It colocalizes with early endosomal markers including Rab4 and Rab11 as well as with the transferrin receptor. Overexpression of the carboxyl-terminal region of RCP, which contains the Rab4- and Rab11-interacting domain, results in a dramatic tubulation of the transferrin compartment. Furthermore, expression of this mutant causes a significant reduction in endosomal recycling without affecting ligand uptake or degradation in quantitative assays. RCP is a homologue of Rip11 and therefore belongs to the recently described Rab11-FIP family.

  9. Immunocontraceptive potential of recombinantly expressed minimized chicken riboflavin carrier protein (mini-RCP) in rodents.

    Science.gov (United States)

    Subramanian, Sarada; Karandeb, Anjali A; Adiga, P Radhakantha

    2004-12-01

    Chicken riboflavin carrier protein (RCP; 219 AA) harbours four linear epitopes, constituted by the peptide residues 3-23, 64-83, 130-147 and 200-219. Antibodies to these sequences bioneutralize maternal RCP and provide protection from pregnancy in rodents. In order to overcome the major histocompatibility complex-dependent variability in immune response often encountered with use of single peptides for vaccination in genetically outbred populations, we have assembled a novel synthetic gene, incorporating in tandem the nucleotide sequences coding for all the four neutralizing epitopes of chicken RCP and expressed in Escherichia coli. The gene product, mini-RCP has been characterized for its immunogenic properties and contraceptive potential in rodents. Immunization of rabbits and rats led to generation of antibodies against individual peptide components, as determined by enzyme-linked-immunosorbent assay (ELISA). However, immunized rats carried pregnancy to term and delivered healthy offsprings. Antisera from these rats exhibited decreased affinity of binding to the native protein. These findings suggest that the prospects of covalently-linked epitope peptides need to be cautiously evaluated during the design and development of peptide-based vaccines.

  10. Receptor component protein (RCP): a member of a multi-protein complex required for G-protein-coupled signal transduction.

    Science.gov (United States)

    Prado, M A; Evans-Bain, B; Dickerson, I M

    2002-08-01

    The calcitonin-gene-related peptide (CGRP) receptor component protein (RCP) is a 148-amino-acid intracellular protein that is required for G-protein-coupled signal transduction at receptors for the neuropeptide CGRP. RCP works in conjunction with two other proteins to constitute a functional CGRP receptor: calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein 1 (RAMP1). CRLR has the stereotypical seven-transmembrane topology of a G-protein-coupled receptor; it requires RAMP1 for trafficking to the cell surface and for ligand specificity, and requires RCP for coupling to the cellular signal transduction pathway. We have made cell lines that expressed an antisense construct of RCP and determined that CGRP-mediated signal transduction was reduced, while CGRP binding was unaffected. Furthermore, signalling at two other endogenous G-protein-coupled receptors was unaffected, suggesting that RCP was specific for a limited subset of receptors.

  11. Research and Design of Graduation Management Platform of Higher Vocational Colleges Based on SSH Framework%基于SSH框架的高等职业院校毕业管理平台的研究与设计

    Institute of Scientific and Technical Information of China (English)

    蔺小清

    2014-01-01

    本文研究目标是设计一个基于SSH框架的职业院校毕业管理平台,该平台完善了职业本科院校实习过程管理、论文质量的管理。%The goal of this paper is to design a graduation management platform of higher vocational college based on SSH framework. This platform can improve the internship management and thesis quality management of higher vocational colleges.

  12. Future changes in precipitation of the baiu season under RCP scenarios

    Science.gov (United States)

    Okada, Y.; Takemi, T.; Ishikawa, H.

    2014-12-01

    Recently, the relationship between global warming and rainfall during the rainy season, which called the baiu in Japan, has been attracting attention in association with heavy rainfall in this period. In the Innovative Program of Climate Change Projection for the 21st Century, many studies show a delay in the northward march of the baiu front, and significant increase of daily precipitation amounts around western Japan during the late baiu season (e.g., Kusunoki et al. 2011, Kanada et al. 2012). The future climate experiment in these studies was performed under the IPCC SRES A1B scenarios for global warming conditions. In this study, we discuss the future changes in precipitation using calculated 60km-mesh model (MRI-AGCM3.2H) under Representative Concentration Pathways (RCP) scenarios. Support of this dataset is provided by the Meteorological Research Institute (MRI). These dataset are calculated by setting the Yoshimura (YS) scheme mainly.Seasonal progression of future precipitation generally indicates the northward in RCP2.6 and 4.5 scenarios, around western Japan. In RCP6.0 scenario, precipitation intensity is weak compared to the other scenarios. RCP8.5 scenario is calculated by setting three different cumulus schemes (YS, Arakawa-Schubert (AS), and Kain-Fritsch (KF) schemes). RCP8.5 configured in YS scheme showed that the rainband associated with the baiu front is not clear. Moreover, peak is remarkable during late June. In AS scheme, the precipitation area stagnates around 30 N until August. And it in KF scheme shows gradual northward migration.This work was conducted under the Program for Risk Information on Climate Change supported by the Ministry of Education, Culture, Sports, Science, and Technology-Japan (MEXT).

  13. Direct interactions between calcitonin-like receptor (CLR) and CGRP-receptor component protein (RCP) regulate CGRP receptor signaling.

    Science.gov (United States)

    Egea, Sophie C; Dickerson, Ian M

    2012-04-01

    Calcitonin gene-related peptide (CGRP) is a neuropeptide with multiple neuroendocrine roles, including vasodilation, migraine, and pain. The receptor for CGRP is a G protein-coupled receptor (GPCR) that requires three proteins for function. CGRP binds to a heterodimer composed of the GPCR calcitonin-like receptor (CLR) and receptor activity-modifying protein (RAMP1), a single transmembrane protein required for pharmacological specificity and trafficking of the CLR/RAMP1 complex to the cell surface. In addition, the CLR/RAMP1 complex requires a third protein named CGRP-receptor component protein (RCP) for signaling. Previous studies have demonstrated that depletion of RCP from cells inhibits CLR signaling, and in vivo studies have demonstrated that expression of RCP correlates with CLR signaling and CGRP efficacy. It is not known whether RCP interacts directly with CLR to exert its effect. The current studies identified a direct interaction between RCP and an intracellular domain of CLR using yeast two-hybrid analysis and coimmunoprecipitation. When this interacting domain of CLR was expressed as a soluble fusion protein, it coimmunoprecipitated with RCP and inhibited signaling from endogenous CLR. Expression of this dominant-negative domain of CLR did not significantly inhibit trafficking of CLR to the cell surface, and thus RCP may not have a chaperone function for CLR. Instead, RCP may regulate CLR signaling in the cell membrane, and direct interaction between RCP and CLR is required for CLR activation. To date, RCP has been found to interact only with CLR and represents a novel neuroendocrine regulatory step in GPCR signaling.

  14. 产业技术创新平台系统模型框架与构成要素分析%Research on the System Model Framework and Elements of Industry Technology Innovative Platform

    Institute of Scientific and Technical Information of China (English)

    汪志波

    2012-01-01

    Based on the connotation and characteristics analysis of innovation platform, from the perspective of systematic structure and innovation process, the system model framework of platform is constructed, and the research on resource allo-cation, system target, input - output and environment of innovative platform system is carried out. The tight link of innova-tion platform subsystems has been discussed. The model means that the platform is the system of integrating synergic effects of different subsystems such as platform innovation decision making, technology and knowledge innovation, achievement transformation and technology&knowledge diffusion, monitoring and evaluation.%在分析产业技术创新平台内涵和特征基础上,基于系统结构与创新过程的视角,构建了产业技术创新平台系统模型的基本框架,研究了创新平台系统的资源配置功能、系统目标、输入输出与环境.探讨了平台各系统之间的紧密联系,认为平台决策、技术知识创新、成果转化与扩散、监测与评价等是产业技术创新平台不同系统之间协同作用的集成体系.

  15. Regional climate change over South Korea projected by the HadGEM2-AO and WRF model chain under RCP emission scenarios

    Science.gov (United States)

    Ahn, Joong-Bae; Im, Eun-Soon; Jo, Sera

    2017-04-01

    This study assesses the regional climate projection newly projected within the framework of the national downscaling project in South Korea. The fine-scale climate information (12.5 km) is produced by dynamical downscaling of the HadGEM2-AO global projections forced by the representative concentration pathway (RCP4.5 and 8.5) scenarios using the Weather Research and Forecasting (WRF) modeling system. Changes in temperature and precipitation in terms of long-term trends, daily characteristics and extremes are presented by comparing two 30 yr periods (2041-2070 vs. 2071-2100). The temperature increase presents a relevant trend, but the degree of warming varies in different periods and emission scenarios. While the temperature distribution from the RCP8.5 projection is continuously shifted toward warmer conditions by the end of the 21st century, the RCP4.5 projection appears to stabilize warming in accordance with emission forcing. This shift in distribution directly affects the magnitude of extremes, which enhances extreme hot days but reduces extreme cold days. Precipitation changes, however, do not respond monotonically to emission forcing, as they exhibit less sensitivity to different emission scenarios. An enhancement of high intensity precipitation and a reduction of weak intensity precipitation are discernible, implying an intensified hydrologic cycle. Changes in return levels of annual maximum precipitation suggest an increased probability of extreme precipitation with 20 yr and 50 yr return periods. Acknowledgement : This work was funded by the Korea Meteorological Administration Research and Development Program under grant KMIPA 2015-2081

  16. Helios: a Multi-Purpose LIDAR Simulation Framework for Research, Planning and Training of Laser Scanning Operations with Airborne, Ground-Based Mobile and Stationary Platforms

    Science.gov (United States)

    Bechtold, S.; Höfle, B.

    2016-06-01

    In many technical domains of modern society, there is a growing demand for fast, precise and automatic acquisition of digital 3D models of a wide variety of physical objects and environments. Laser scanning is a popular and widely used technology to cover this demand, but it is also expensive and complex to use to its full potential. However, there might exist scenarios where the operation of a real laser scanner could be replaced by a computer simulation, in order to save time and costs. This includes scenarios like teaching and training of laser scanning, development of new scanner hardware and scanning methods, or generation of artificial scan data sets to support the development of point cloud processing and analysis algorithms. To test the feasibility of this idea, we have developed a highly flexible laser scanning simulation framework named Heidelberg LiDAR Operations Simulator (HELIOS). HELIOS is implemented as a Java library and split up into a core component and multiple extension modules. Extensible Markup Language (XML) is used to define scanner, platform and scene models and to configure the behaviour of modules. Modules were developed and implemented for (1) loading of simulation assets and configuration (i.e. 3D scene models, scanner definitions, survey descriptions etc.), (2) playback of XML survey descriptions, (3) TLS survey planning (i.e. automatic computation of recommended scanning positions) and (4) interactive real-time 3D visualization of simulated surveys. As a proof of concept, we show the results of two experiments: First, a survey planning test in a scene that was specifically created to evaluate the quality of the survey planning algorithm. Second, a simulated TLS scan of a crop field in a precision farming scenario. The results show that HELIOS fulfills its design goals.

  17. Mathematizing Process of Junior High School Students to Improve Mathematics Literacy Refers PISA on RCP Learning

    Science.gov (United States)

    Wardono; Mariani, S.; Hendikawati, P.; Ikayani

    2017-04-01

    Mathematizing process (MP) is the process of modeling a phenomenon mathematically or establish the concept of a phenomenon. There are two mathematizing that is Mathematizing Horizontal (MH) and Mathematizing Vertical (MV). MH as events changes contextual problems into mathematical problems, while MV is the process of formulation of the problem into a variety of settlement mathematics by using some appropriate rules. Mathematics Literacy (ML) is the ability to formulate, implement and interpret mathematics in various contexts, including the capacity to perform reasoning mathematically and using the concepts, procedures, and facts to describe, explain or predict phenomena incident. If junior high school students are conditioned continuously to conduct mathematizing activities on RCP (RME-Card Problem) learning, it will be able to improve ML that refers PISA. The purpose of this research is to know the capability of the MP grade VIII on ML content shape and space with the matter of the cube and beams with RCP learning better than the scientific learning, upgrade MP grade VIII in the issue of the cube and beams with RCP learning better than the scientific learning in terms of cognitive styles reflective and impulsive the MP grade VIII with the approach of the RCP learning in terms of cognitive styles reflective and impulsive This research is the mixed methods model concurrent embedded. The population in this study, i.e., class VIII SMPN 1 Batang with sample two class. Data were taken with the observation, interviews, and tests and analyzed with a different test average of one party the right qualitative and descriptive. The results of this study demonstrate the capability of the MP student with RCP learning better than the scientific learning, upgrade MP with RCP learning better compare with scientific learning in term cognitive style of reflective and impulsive. The subject of the reflective group top, middle, and bottom can meet all the process of MH indicators are

  18. Measuring Progress on the Control of Porcine Reproductive and Respiratory Syndrome (PRRS at a Regional Level: The Minnesota N212 Regional Control Project (Rcp as a Working Example.

    Directory of Open Access Journals (Sweden)

    Pablo Valdes-Donoso

    Full Text Available Due to the highly transmissible nature of porcine reproductive and respiratory syndrome (PRRS, implementation of regional programs to control the disease may be critical. Because PRRS is not reported in the US, numerous voluntary regional control projects (RCPs have been established. However, the effect of RCPs on PRRS control has not been assessed yet. This study aims to quantify the extent to which RCPs contribute to PRRS control by proposing a methodological framework to evaluate the progress of RCPs. Information collected between July 2012 and June 2015 from the Minnesota Voluntary Regional PRRS Elimination Project (RCP-N212 was used. Demography of premises (e.g. composition of farms with sows = SS and without sows = NSS was assessed by a repeated analysis of variance. By using general linear mixed-effects models, active participation of farms enrolled in the RCP-N212, defined as the decision to share (or not to share PRRS status, was evaluated and used as a predictor, along with other variables, to assess the PRRS trend over time. Additionally, spatial and temporal patterns of farmers' participation and the disease dynamics were investigated. The number of farms enrolled in RCP-N212 and its geographical coverage increased, but the proportion of SS and NSS did not vary significantly over time. A significant increasing (p<0.001 trend in farmers' decision to share PRRS status was observed, but with NSS producers less willing to report and a large variability between counties. The incidence of PRRS significantly (p<0.001 decreased, showing a negative correlation between degree of participation and occurrence of PRRS (p<0.001 and a positive correlation with farm density at the county level (p = 0.02. Despite a noted decrease in PRRS, significant spatio-temporal patterns of incidence of the disease over 3-weeks and 3-kms during the entire study period were identified. This study established a systematic approach to quantify the effect of RCPs on

  19. Platform development supportedby gaming

    DEFF Research Database (Denmark)

    Mikkola, Juliana Hsuan; Hansen, Poul H. Kyvsgård

    2007-01-01

    The challenge of implementing industrial platforms in practice can be described as a configuration problem caused by high number of variables, which often have contradictory influences on the total performance of the firm. Consequently, the specific platform decisions become extremely complex......, possibly increasing the strategic risks for the firm. This paper reports preliminary findings on platform management process at LEGO, a Danish toy company.  Specifically, we report the process of applying games combined with simulations and workshops in the platform development. We also propose a framework......, based on the portfolio management thinking, to measure the degree of modularity embedded in a given platform and to what extent it is aligned with other platforms....

  20. 一种改进的RCP算法%Modified RCP Algorithm

    Institute of Scientific and Technical Information of China (English)

    陈栩杉; 武欣嵘; 周伟; 周斌; 吴凯

    2011-01-01

    RCP is a rate-based explicit congestion control algorithm.It performs well on the efficiency convergence and fairness convergence and has a good performance under the multiplebottleneck network topology environment.But some researches show that when a new flow joins in the network,there exists in RCP algorithm severe instantaneous overloading,resulting in packet loss.The source control was adjusted to the algorithm and S-RCP algorithm proposed. Theoretic analysis and simulation results confirm that S-RCP algorithm solves the instantaneous overloading to a certain extent and also eliminates the packet loss.%RCP算法是一种基于速率的显式拥塞控制算法,具有较好的效率和公平收敛性,在多瓶颈网络拓扑环境下也有很好的性能。但是研究表明,当一个新流加入网络时,RCP算法存在严重的瞬态过载现象,从而导致丢包的发生。文中通过在原有RCP算法基础上调整了源端控制的方式,提出了S-RCP算法。理论分析和仿真结果表明,S-RCP算法一定程度上解决了瞬态过载现象,基本消除了丢包现象。

  1. CGRP-RCP, a novel protein required for signal transduction at calcitonin gene-related peptide and adrenomedullin receptors.

    Science.gov (United States)

    Evans, B N; Rosenblatt, M I; Mnayer, L O; Oliver, K R; Dickerson, I M

    2000-10-06

    It is becoming clear that receptors that initiate signal transduction by interacting with G-proteins do not function as monomers, but often require accessory proteins for function. Some of these accessory proteins are chaperones, required for correct transport of the receptor to the cell surface, but the function of many accessory proteins remains unknown. We determined the role of an accessory protein for the receptor for calcitonin gene-related peptide (CGRP), a potent vasodilator neuropeptide. We have previously shown that this accessory protein, the CGRP-receptor component protein (RCP), is expressed in CGRP responsive tissues and that RCP protein expression correlates with the biological efficacy of CGRP in vivo. However, the function of RCP has remained elusive. In this study stable cell lines were made that express antisense RCP RNA, and CGRP- and adrenomedullin-mediated signal transduction were greatly reduced. However, the loss of RCP did not effect CGRP binding or receptor density, indicating that RCP did not behave as a chaperone but was instead coupling the CGRP receptor to downstream effectors. A candidate CGRP receptor named calcitonin receptor-like receptor (CRLR) has been identified, and in this study RCP co-immunoprecipitated with CRLR indicating that these two proteins interact directly. Since CGRP and adrenomedullin can both signal through CRLR, which has been previously shown to require a chaperone protein for function, we now propose that a functional CGRP or adrenomedullin receptor consists of at least three proteins: the receptor (CRLR), the chaperone protein (RAMP), and RCP that couples the receptor to the cellular signal transduction pathway.

  2. Grout Impregnation of Pre-Placed Recycled Concrete Pavement (RCP) for Rapid Repair of Deteriorated Portland Cement Concrete Airfield Pavement

    Science.gov (United States)

    2007-04-01

    Hammitt (1985) also reports a high failure rate when using cold mix asphalt for crater repairs and recommended that it be abandoned as a technique...cement-treated base, embankment base material, and aggregate for asphalt paving mixtures . RCP has been used successfully for all of these types of...that recycled asphalt pavement ( RAP ) and RCP have a substantial history of usage in pavement construction. He reports that cost savings of 20 to

  3. The Projection of Temperature and Precipitation over China under RCP Scenarios using a CMIP5 Multi-Model Ensemble

    Institute of Scientific and Technical Information of China (English)

    XU Chong-Hai; XU Ying

    2012-01-01

    Climate changes in 21st century China are described based on the projections of 11 climate models under Representative Concentration Pathway (RCP) scenarios. The results show that warming is expected in all regions of China under the RCP scenarios, with the northern regions showing greater warming than the southern regions. The warming tendency from 2011 to 2100 is 0.06°C/10 a for RCP2.6, 0.24°C/10 a for RCP4.5, and 0.63°C/10 a for RCP8.5. The projected time series of annual temperature have similar variation tendencies as the new greenhouse gas (GHG) emission scenario pathways, and the warming under the lower emission scenarios is less than under the higher emission scenarios. The regional averaged precipitation will increase, and the increasing precipitation in the northern regions is significant and greater than in the southern regions in China. It is noted that precipitation will tend to decrease in the southern parts of China during the period of 2011–2040, especially under RCP8.5. Compared with the changes over the globe and some previous projections, the increased warming and precipitation over China is more remarkable under the higher emission scenarios. The uncertainties in the projection are unavoidable, and further analyses are necessary to develop a better understanding of the future changes over the region.

  4. A Typology of Multi-sided Platforms

    DEFF Research Database (Denmark)

    Staykova, Kalina Stefanova; Damsgaard, Jan

    2015-01-01

    exemplary cases which allow us to illustrate the platform heterogeneity and to support new MSPs typology. As examples we include a physical two-sided platform (Gatwick Airport) that adds a third side, a digital one-sided platform transformed into being two-sided (Pingit) and a digital one-sided platform......In this paper we address how the composition of a platform impacts the platform’s business model. By platform’s business model we mean platform features, platform architecture and platform governance. To this end, we construct the Platform Business Model Framework. We apply the framework to three...... in several configurations. The particular platform architecture can explain the difficulties in designing a viable business models for platforms....

  5. Minilaparotomy radical cystoprostatectomy (Minilap RCP) in the surgical management of urinary bladder carcinoma: early experience.

    Science.gov (United States)

    Rawal, Sudhir; Raghunath, S K; Khanna, Samir; Jain, Deepak; Kaul, Rakesh; Kumar, Prem; Chhabra, Rakesh; Bhushan, Kirti

    2008-09-01

    To assess the feasibility of minilaparotomy for radical cystoprostatectomy (RCP) and urinary diversion in the management of urinary bladder carcinoma. A total of 45 consecutive patients with muscle invasive urinary bladder cancer underwent RCP and urinary diversion [32, 12 and 1 patients with pitchers pot orthotopic neobladder (NB), ileal conduit (IC) and sigma rectal pouch respectively], between May 2006 and June 2007, using 8-12 cm infraumbilical midline vertical incision from pubic symphysis, were prospectively analyzed for technical feasibility, operative time, blood loss, intraoperative and postoperative complications and return of bowel function. All the patients were males with average age of 59.65 years (44-79 years) and average body mass index of 23.97(17.7-29.5). The length of the incision was 8, 10 and 12 cm in 4, 39 and 2 patients, respectively. The average number of lymph nodes removed on the right and left side was 14 and 16, respectively. The average blood loss was 1046 ml (595-2100 ml). Return of bowel sounds was observed on an average by second postoperative day (1-5 days). Average postoperative stay was 14 days (range 10-24 days) for NB and 7 days (6-8 days) for IC patients. One (2.22%) patient died on the 18th postoperative day due to septicemia and acute renal failure. Minilaparotomy RCP is technically feasible without compromising the oncological principles. Complete removal of urachus and adequate clearance of pelvic lymph nodes is not difficult with the small incision. Early restoration of bowel function, early postoperative recovery and good cosmesis seem to be the main advantages.

  6. NASA uses Eclipse RCP Applications for Experiments on the International Space Station

    Science.gov (United States)

    Cohen, Tamar

    2013-01-01

    Eclipse is going to space for the first time in 2013! The International Space Station (ISS) is used as a site for experiments any software developed as part of these experiments has to comply with extensive and strict user interface guidelines. NASA Ames Research Center's Intelligent Robotics Group is doing 2 sets of experiments, both with astronauts using Eclipse RCP applications to remotely control robots. One experiment will control SPHERES with an Android Smartphone on the ISS the other experiment will control a K10 rover on Earth.

  7. The design and synthesis of a hydrophilic core-shell-shell structured magnetic metal-organic framework as a novel immobilized metal ion affinity platform for phosphoproteome research.

    Science.gov (United States)

    Zhao, Man; Deng, Chunhui; Zhang, Xiangmin

    2014-06-14

    In this work, polydopamine (PDA)-coated magnetic microspheres with surface modification of zirconium-based MOFs were synthesized for the first time. The as-synthesized Fe3O4@PDA@Zr-MOF composites were successfully applied as a novel immobilized metal ion affinity platform for phosphoproteome research.

  8. Expression of calcitonin gene-related peptide-receptor component protein (CGRP-RCP) in human myometrium in differing physiological states and following misoprostol administration.

    Science.gov (United States)

    Goharkhay, Nina; Lu, Jing; Felix, Juan C; Wing, Deborah A

    2007-09-01

    Our objective was to assess relative expression levels of mRNA for calcitonin gene-related peptide-receptor component protein (CGRP-RCP) in human myometrium in various physiological states. Using semiquantitative reverse transcriptase polymerase chain reaction (RT-PCR), we analyzed myometrial samples from 46 women (10 menopausal, 10 nongravid premenopausal, 19 gravidae, and 7 premenopausal misoprostol-treated nongravid women) for the specific expression of CGRP-RCP mRNA. The expression of CGRP-RCP was significantly increased in gravid compared with nongravid myometrium ( P RCP expression were found among the other study groups. We concluded that the increased mRNA expression CGRP-RCP in gravid myometrium supports the possibility of involvement of CGRP in the control of myometrial contractility. Additional studies are necessary to evaluate the exact mechanism of action of CGRP and CGRP-RCP in human myometrium.

  9. FIP1/RCP binding to Golgin-97 regulates retrograde transport from recycling endosomes to the trans-Golgi network.

    Science.gov (United States)

    Jing, Jian; Junutula, Jagath R; Wu, Christine; Burden, Jemima; Matern, Hugo; Peden, Andrew A; Prekeris, Rytis

    2010-09-01

    Many proteins are retrieved to the trans-Golgi Network (TGN) from the endosomal system through several retrograde transport pathways to maintain the composition and function of the TGN. However, the molecular mechanisms involved in these distinct retrograde pathways remain to be fully understood. Here we have used fluorescence and electron microscopy as well as various functional transport assays to show that Rab11a/b and its binding protein FIP1/RCP are both required for the retrograde delivery of TGN38 and Shiga toxin from early/recycling endosomes to the TGN, but not for the retrieval of mannose-6-phosphate receptor from late endosomes. Furthermore, by proteomic analysis we identified Golgin-97 as a FIP1/RCP-binding protein. The FIP1/RCP-binding domain maps to the C-terminus of Golgin-97, adjacent to its GRIP domain. Binding of FIP1/RCP to Golgin-97 does not affect Golgin-97 recruitment to the TGN, but appears to regulate the targeting of retrograde transport vesicles to the TGN. Thus, we propose that FIP1/RCP binding to Golgin-97 is required for tethering and fusion of recycling endosome-derived retrograde transport vesicles to the TGN.

  10. Analysis of the change in temperature trends in Subansiri River basin for RCP scenarios using CMIP5 datasets

    Science.gov (United States)

    Shivam; Goyal, Manish Kumar; Sarma, Arup Kumar

    2017-08-01

    This study focuses on changes in the maximum and minimum temperature over the Subansiri River basin for different climate change scenarios. For the study, dataset from Intergovernmental Panel on Climate Change (IPCC) fifth assessment report (AR5) (i.e., coupled model intercomparison project phase five (CMIP5) dataset with representative concentration pathway (RCP) scenarios) were utilized. Long-term (2011-2100) maximum temperature ( T max) and minimum temperature (Tmin) time series were generated using the statistical downscaling technique for low emission scenario (RCP2.6), moderate emission scenario (RCP6.0), and extreme emission scenario (RCP8.5). Trends and change of magnitude in T max, T min, and diurnal temperature range (DTR) were analyzed for different interdecadal time scales (2011-2100, 2011-2040, 2041-2070, 2070-2100) using Mann-Kendall non-parametric test and Sen's slope estimator, respectively. The temperature data series for the observed duration (1981-2000) has been found to show increasing trends in T max and T min at both annual and monthly scale. Trend analysis of downscaled temperature for the period 2011-2100 shows increase in annual maximum temperature and annual minimum temperature for all the selected RCP scenarios; however, on the monthly scale, T max and T min have been seen to have decreasing trends in some months.

  11. Analysis of the change in temperature trends in Subansiri River basin for RCP scenarios using CMIP5 datasets

    Science.gov (United States)

    Shivam; Goyal, Manish Kumar; Sarma, Arup Kumar

    2016-06-01

    This study focuses on changes in the maximum and minimum temperature over the Subansiri River basin for different climate change scenarios. For the study, dataset from Intergovernmental Panel on Climate Change (IPCC) fifth assessment report (AR5) (i.e., coupled model intercomparison project phase five (CMIP5) dataset with representative concentration pathway (RCP) scenarios) were utilized. Long-term (2011-2100) maximum temperature (T max) and minimum temperature (Tmin) time series were generated using the statistical downscaling technique for low emission scenario (RCP2.6), moderate emission scenario (RCP6.0), and extreme emission scenario (RCP8.5). Trends and change of magnitude in T max, T min, and diurnal temperature range (DTR) were analyzed for different interdecadal time scales (2011-2100, 2011-2040, 2041-2070, 2070-2100) using Mann-Kendall non-parametric test and Sen's slope estimator, respectively. The temperature data series for the observed duration (1981-2000) has been found to show increasing trends in T max and T min at both annual and monthly scale. Trend analysis of downscaled temperature for the period 2011-2100 shows increase in annual maximum temperature and annual minimum temperature for all the selected RCP scenarios; however, on the monthly scale, T max and T min have been seen to have decreasing trends in some months.

  12. RCP: a novel probe design bias correction method for Illumina Methylation BeadChip.

    Science.gov (United States)

    Niu, Liang; Xu, Zongli; Taylor, Jack A

    2016-09-01

    The Illumina HumanMethylation450 BeadChip has been extensively utilized in epigenome-wide association studies. This array and its successor, the MethylationEPIC array, use two types of probes-Infinium I (type I) and Infinium II (type II)-in order to increase genome coverage but differences in probe chemistries result in different type I and II distributions of methylation values. Ignoring the difference in distributions between the two probe types may bias downstream analysis. Here, we developed a novel method, called Regression on Correlated Probes (RCP), which uses the existing correlation between pairs of nearby type I and II probes to adjust the beta values of all type II probes. We evaluate the effect of this adjustment on reducing probe design type bias, reducing technical variation in duplicate samples, improving accuracy of measurements against known standards, and retention of biological signal. We find that RCP is statistically significantly better than unadjusted data or adjustment with alternative methods including SWAN and BMIQ. We incorporated the method into the R package ENmix, which is freely available from the Bioconductor website (https://www.bioconductor.org/packages/release/bioc/html/ENmix.html). niulg@ucmail.uc.edu Supplementary data are available at Bioinformatics online. Published by Oxford University Press 2016. This work is written by US Government employees and is in the public domain in the US.

  13. Characterization of a balanced reciprocal translocation, rcp(9;11)(q27;q11) in cattle.

    Science.gov (United States)

    De Lorenzi, L; De Giovanni, A; Molteni, L; Denis, C; Eggen, A; Parma, P

    2007-01-01

    Cytogenetic analysis of a phenotypically normal young bull from Marchigiana breed revealed the presence of an abnormal karyotype. The observation of longer and smaller chromosomes than BTA1 and BTA29, respectively in all metaphases suggested the presence of a reciprocal translocation. RBG-banding confirmed this hypothesis revealing the involvement of BTA9 and BTA11. FISH analyses using cattle-specific BAC clones (474A12 and 293G09 for BTA9; 035D03 for BTA11) identified rcp(9;11)(q27;q11) in the two regions affected. Moreover analyses performed on both parents established the 'de novo' origin of the anomaly. Comparison with human homologue sequences (HSA6q24.3-->q25.3 for BTA9q27 and HSA2q11.1-->q12.1 for BTA11q11) revealed that both breakpoint regions are gene rich as up to date at least 200 genes have been localized in these regions. Thus, further analyses are required to identify the sequences disrupted by the breakpoints and to verify their consequences on rcp carrier phenotype. Copyright (c) 2008 S. Karger AG, Basel.

  14. Predictable Technique to Register Retruded Contact Position (RCP) Using a Disposable Jaw Relation Recording Device.

    Science.gov (United States)

    Daher, Tony; Lobel, William A; Massad, Joseph; Ahuja, Swati; Danilov, Zarko Jack

    2015-05-01

    The dental literature presents various definitions and techniques to describe and register centric relation (CR) or centric occlusion (CO). Briefly reviewing the literature in relation to CR, this article proposes the use of the term retruded contact position (RCP), clinically defined as retruded, unstrained, repeatable position and where the mandibular movements start when a Gothic arch tracing is used. With this clinical definition, a technique can be easily selected that meets all the requirements of such position. The article discusses the use of a jaw recorder that is an intraorally graphic recording device that results in a tracing of mandibular movements in one plane, with the apex of the tracing indicating the retruded, unstrained, and repeatable relationship. The intersection of the arcs produced by the right and left working movement form the apex of the Gothic arch tracing. Several clinical situations using the jaw recorder are described. Clinicians can now quickly and accurately record RCP, balance complete, partial, or implant dentures, and orthopedically reposition the mandible. The technique achieves highly reliable and reproducible results.

  15. Pre-test analysis of ATLAS SBO with RCP seal leakage scenario using MARS code

    Energy Technology Data Exchange (ETDEWEB)

    Pham, Quang Huy; Lee, Sang Young; Oh, Seung Jong [KEPCO International Nuclear Graduate School, Ulsan (Korea, Republic of)

    2015-10-15

    This study presents a pre-test calculation for the Advanced Thermal-hydraulic Test Loop for Accident Simulation (ATLAS) SBO experiment with RCP seal leakage scenario. Initially, turbine-driven auxfeed water pumps are used. Then, outside cooling water injection method is used for long term cooling. The analysis results would be useful for conducting the experiment to verify the APR 1400 extended SBO optimum mitigation strategy using outside cooling water injection in future. The pre-test calculation for ATLAS extended SBO with RCP seal leakage and outside cooling water injection scenario is performed. After Fukushima nuclear accident, the capability of coping with the extended station blackout (SBO) becomes important. Many NPPs are applying FLEX approach as main coping strategies for extended SBO scenarios. In FLEX strategies, outside cooling water injection to reactor cooling system (RCS) and steam generators (SGs) is considered as an effective method to remove residual heat and maintain the inventory of the systems during the accident. It is worthwhile to examine the soundness of outside cooling water injection method for extended SBO mitigation by both calculation and experimental demonstration. From the calculation results, outside cooling water injection into RCS and SGs is verified as an effective method during extended SBO when RCS and SGs depressurization is sufficiently performed.

  16. Technical framework of general comprehensive information management platform of IOT%通用物联网综合信息管理平台的技术架构

    Institute of Scientific and Technical Information of China (English)

    陈丽; 刘彤

    2013-01-01

      介绍了通用物联网综合信息管理平台的技术架构,对包括感知层的数据采集汇接设备、网络层的多协议中间件和应用层的跨平台管理系统软件进行了深入研究,给出了Siteview6200型C5I iotWare网络数据采集汇接设备、nMedias中间件和iotWare物联网应用软件平台的主要功能和应用特点。%The paper introduces the technical framework of general comprehensive information management platform of IOT, and makes an in-depth study about the data collection tandems equipment of perception layer, multi-protocol middleware of network layer and cross-platform management software system of application layer. The paper describes main functions and application characteristics of the Siteview6200-type C5I iotWare network data collection tandems equipment, nMedias middleware and iotWare IOT application platform.

  17. 一个可视化并行程序开发平台的构架及实现%Framework and Realization of A Visual Parallel Programming Platform

    Institute of Scientific and Technical Information of China (English)

    胡志刚; 邹恒华; 钟掘

    2001-01-01

    Parallel computing has been an extremely effective method to solve many large science and engineering problems. But due to their highly technical,most parallel software can't satisfy the needs of users,especially nonprofessional users. In view of the present situation,this paper presents a framework of a visual parallel programming platform.The platform consists of task description and tasks control & schedule process. In addition,this paper simply explains the realization of some data structures and shows an example of the platform.%并行计算已经成为当前解决许多大型科学和工程计算问题的十分有效的方式,但当前并行软件由于其技术性太强,而无法满足广大、特别是普通用户的需要。基于这一点,文章提出了一个可视化的并行程序开发平台的构架。该平台由任务描述和任务控制调度进程组成。文章还简单地说明了该系统平台的数据结构实现及该平台的运用实例。

  18. An Rpb4/Rpb7-like complex in yeast RNA polymerase III contains the orthologue of mammalian CGRP-RCP.

    Science.gov (United States)

    Siaut, Magali; Zaros, Cécile; Levivier, Emilie; Ferri, Maria-Laura; Court, Magali; Werner, Michel; Callebaut, Isabelle; Thuriaux, Pierre; Sentenac, André; Conesa, Christine

    2003-01-01

    The essential C17 subunit of yeast RNA polymerase (Pol) III interacts with Brf1, a component of TFIIIB, suggesting a role for C17 in the initiation step of transcription. The protein sequence of C17 (encoded by RPC17) is conserved from yeasts to humans. However, mammalian homologues of C17 (named CGRP-RCP) are known to be involved in a signal transduction pathway related to G protein-coupled receptors, not in transcription. In the present work, we first establish that human CGRP-RCP is the genuine orthologue of C17. CGRP-RCP was found to functionally replace C17 in Deltarpc17 yeast cells; the purified mutant Pol III contained CGRP-RCP and had a decreased specific activity but initiated faithfully. Furthermore, CGRP-RCP was identified by mass spectrometry in a highly purified human Pol III preparation. These results suggest that CGRP-RCP has a dual function in mammals. Next, we demonstrate by genetic and biochemical approaches that C17 forms with C25 (encoded by RPC25) a heterodimer akin to Rpb4/Rpb7 in Pol II. C17 and C25 were found to interact genetically in suppression screens and physically in coimmunopurification and two-hybrid experiments. Sequence analysis and molecular modeling indicated that the C17/C25 heterodimer likely adopts a structure similar to that of the archaeal RpoE/RpoF counterpart of the Rpb4/Rpb7 complex. These RNA polymerase subunits appear to have evolved to meet the distinct requirements of the multiple forms of RNA polymerases.

  19. Impacts of climate change on streamflows under RCP scenarios: A case study in Xin River Basin, China

    Science.gov (United States)

    Zhang, Yuqing; You, Qinglong; Chen, Changchun; Ge, Jing

    2016-09-01

    Researchers often examine hydro-climatological processes via Global Circulation Model (GCM) and hydrological model, which have been shown to benefit water resources management and prediction, especially at the basin scale. In this study, the Soil and Water Assessment Tool (SWAT) and Statistical Downscaling Method (SDSM) were integrated and applied to estimate streamflows in the Xin River Basin, China, based on climate change scenarios downscaled from different GCMs (BCC-CSM1.1, CanESM2, and NorESM1-M) under three Representative Concentration Pathways (RCPs). Results confirmed that the calibrated SWAT model accurately depicts hydrological processes features at daily, monthly, and yearly scales. Three GCMs based on the calibrated SDSM showed that temperature is continually increasing in the region, however, future precipitation is highly complex and uncertain; there were significant differences among various GCM RCP scenarios. The average of the precipitation in three models showed slight and steady increase trends under RCP2.6 and RCP4.5, but a significant increase under the RCP8.5 scenario. The ensemble average of streamflow in GCMs demonstrated that many RCPs significantly decrease from May to June but increase from August to September relative to the baseline period. The ensemble mean of the multi-GCM indicated that future streamflows under RCP2.6 and RCP4.5 scenarios will be closer to the current streamflow volume. Many RCPs also revealed a significant increase in monthly streamflow dispersion coefficient in October, reflecting a tendency for drought and flood events in that month. The BCC-CSM1.1 and NorESM1-M models showed that streamflows are higher than the baseline with median probability in the future. The low monthly streamflow (10th percentile) processes for each GCM were altogether similar to the baseline, whereas the high monthly streamflows (90th percentile) showed various levels of disparity compared to the baseline.

  20. Teaching Innovation and Use of the ICT in the Teaching-Learning Process within the New Framework of the EHEA, by Means of Moodle Platform

    Science.gov (United States)

    Ciudad-Gómez, Adelaida

    2010-01-01

    The framework of the European Higher Education Area (EHEA) has turned the student into the main protagonist of the new educational scenario, and the teacher into the coordinator of teaching-learning process instead of transmitter of knowledge. In this new model of learning, the use of ICT is facilitating competency-based learning and the…

  1. Moisture-Stable Zn(II) Metal-Organic Framework as a Multifunctional Platform for Highly Efficient CO2 Capture and Nitro Pollutant Vapor Detection.

    Science.gov (United States)

    Chen, Di-Ming; Tian, Jia-Yue; Chen, Min; Liu, Chun-Sen; Du, Miao

    2016-07-20

    A moisture-stable three-dimensional (3D) metal-organic framework (MOF), {(Me2NH2)[Zn2(bpydb)2(ATZ)](DMA)(NMF)2}n (1, where bpydb = 4,4'-(4,4'-bipyridine-2,6-diyl)dibenzoate, ATZ = deprotonated 5-aminotetrazole, DMA = N,N-dimethylacetamide, and NMF = N-methylformamide), with uncoordinated N-donor sites and charged framework skeleton was fabricated. This MOF exhibits interesting structural dynamic upon CO2 sorption at 195 K and high CO2/N2 (127) and CO2/CH4 (131) sorption selectivity at 298 K and 1 bar. Particularly, its CO2/CH4 selectivity is among the highest MOFs for selective CO2 separation. The results of Grand Canonical Monte Carlo (GCMC) simulation indicate that the polar framework contributes to the strong framework-CO2 binding at zero loading, and the tetrazole pillar contributes to the high CO2 uptake capacity at high loading. Furthermore, the solvent-responsive luminescent properties of 1 indicate that it could be utilized as a fluorescent sensor to detect trace amounts of nitrobenzene in both solvent and vapor systems.

  2. Winter climate changes over East Asian region under RCP scenarios using East Asian winter monsoon indices

    Science.gov (United States)

    Hong, Ja-Young; Ahn, Joong-Bae; Jhun, Jong-Ghap

    2017-01-01

    The changes in the winter climatology and variability of the East Asian winter monsoon (EAWM) for the late 21st century (2070-2099) under the Representative Concentration Pathway (RCP) 4.5 and 8.5 scenarios are projected in terms of EAWM indices (EAWMIs). Firstly, the capability of the climate models participating in the Coupled Model Intercomparison Project phase 5 (CMIP5) in simulating the boreal winter climatology and the interannual variability of the EAWM for the late 20th century (1971-2000) is examined. Nine of twenty-three climate models are selected based on the pattern correlations with observation and a multi-model ensemble is applied to the nine model data. Three of twelve EAWMIs that show the most significant temporal correlations between the observation and CMIP5 surface air temperatures are utilized. The ensemble CMIP5 is capable of reproducing the overall features of the EAWM in spite of some biases in the region. The negative correlations between the EAWMIs and boreal winter temperature are well reproduced and 3-5 years of the major interannual variation observed in this region are also well simulated according to power spectral analyses of the simulated indices. The fields regressed onto the indices that resemble the composite strong winter monsoon pattern are simulated more or less weakly in CMIP5 compared to the observation. However, the regressed fields of sea level pressure, surface air temperature, 500-hPa geopotential height, and 300-hPa zonal wind are well established with pattern correlations above 0.83 between CMIP5 and observation data. The differences between RCPs and Historical indicate strong warming, which increases with latitude, ranging from 1 to 5 °C under RCP4.5 and from 3 to 7 °C under RCP8.5 in the East Asian region. The anomalous southerly winds generally become stronger, implying weaker EAWMs in both scenarios. These features are also identified with fields regressed onto the indices in RCPs. The future projections reveal

  3. Winter climate changes over East Asian region under RCP scenarios using East Asian winter monsoon indices

    Science.gov (United States)

    Hong, Ja-Young; Ahn, Joong-Bae; Jhun, Jong-Ghap

    2016-03-01

    The changes in the winter climatology and variability of the East Asian winter monsoon (EAWM) for the late 21st century (2070-2099) under the Representative Concentration Pathway (RCP) 4.5 and 8.5 scenarios are projected in terms of EAWM indices (EAWMIs). Firstly, the capability of the climate models participating in the Coupled Model Intercomparison Project phase 5 (CMIP5) in simulating the boreal winter climatology and the interannual variability of the EAWM for the late 20th century (1971-2000) is examined. Nine of twenty-three climate models are selected based on the pattern correlations with observation and a multi-model ensemble is applied to the nine model data. Three of twelve EAWMIs that show the most significant temporal correlations between the observation and CMIP5 surface air temperatures are utilized. The ensemble CMIP5 is capable of reproducing the overall features of the EAWM in spite of some biases in the region. The negative correlations between the EAWMIs and boreal winter temperature are well reproduced and 3-5 years of the major interannual variation observed in this region are also well simulated according to power spectral analyses of the simulated indices. The fields regressed onto the indices that resemble the composite strong winter monsoon pattern are simulated more or less weakly in CMIP5 compared to the observation. However, the regressed fields of sea level pressure, surface air temperature, 500-hPa geopotential height, and 300-hPa zonal wind are well established with pattern correlations above 0.83 between CMIP5 and observation data. The differences between RCPs and Historical indicate strong warming, which increases with latitude, ranging from 1 to 5 °C under RCP4.5 and from 3 to 7 °C under RCP8.5 in the East Asian region. The anomalous southerly winds generally become stronger, implying weaker EAWMs in both scenarios. These features are also identified with fields regressed onto the indices in RCPs. The future projections reveal

  4. The RCP Information Laboratory (iLab): breaking the cycle of poor data quality.

    Science.gov (United States)

    Croft, Giles P; Williams, John G

    2005-01-01

    A review of data quality in the NHS by the Audit Commission cited a lack of clinician involvement in the validation and use of centrally held activity data as one of the key issues to resolve. The perception that hospital episode statistics cannot support the needs of the individual clinician results in mistrust and disinterest. This in turn leads to under-development of such data from a clinical perspective, and the cycle continues. The RCP Information Laboratory (iLab) aims to address this problem by accessing, analysing and presenting information from these central repositories concerning the activity of visiting individual consultant physicians. With support from iLab staff--an information analyst and a clinician--local data quality issues are highlighted and local solutions sought. The information obtained can be used as an objective measure of activity to support the processes of appraisal and revalidation.

  5. Future climate data from RCP 4.5 and occurrence of malaria in Korea.

    Science.gov (United States)

    Kwak, Jaewon; Noh, Huiseong; Kim, Soojun; Singh, Vijay P; Hong, Seung Jin; Kim, Duckgil; Lee, Keonhaeng; Kang, Narae; Kim, Hung Soo

    2014-10-15

    Since its reappearance at the Military Demarcation Line in 1993, malaria has been occurring annually in Korea. Malaria is regarded as a third grade nationally notifiable disease susceptible to climate change. The objective of this study is to quantify the effect of climatic factors on the occurrence of malaria in Korea and construct a malaria occurrence model for predicting the future trend of malaria under the influence of climate change. Using data from 2001-2011, the effect of time lag between malaria occurrence and mean temperature, relative humidity and total precipitation was investigated using spectral analysis. Also, a principal component regression model was constructed, considering multicollinearity. Future climate data, generated from RCP 4.5 climate change scenario and CNCM3 climate model, was applied to the constructed regression model to simulate future malaria occurrence and analyze the trend of occurrence. Results show an increase in the occurrence of malaria and the shortening of annual time of occurrence in the future.

  6. Hydrological response to climate change: The Pearl River, China under different RCP scenarios

    Directory of Open Access Journals (Sweden)

    Dan Yan

    2015-09-01

    New hydrological insights for the region: Previous studies focussed on annual discharge and extreme flood events in the basin. However it is also important to assess variations in low flow across the basin, because it is suffering from water shortage and salt water intrusion in the dry season. Results indicate a reduction in average low flow under the five climate models. The reduction varies across the basin and is between 6 and 48% for RCP4.5. River discharge in the dry season is projected to decrease throughout the basin. In the wet season, river discharge tends to increase in the middle and lower reaches and decrease in the upper reach of the Pearl River basin. The variation of river discharge is likely to aggravate water stress. Especially the reduction of low flow is problematic as already now the basin experiences temporary water shortages in the delta.

  7. A Model-based Developing Environment for Embedded Platform%面向嵌入式实验平台的模型化开发环境

    Institute of Scientific and Technical Information of China (English)

    范哲意; 周治国; 康怀松; 刘志文

    2013-01-01

    在Eclipse RCP框架和Matlab建模引擎的基础之上,实现了一种针对嵌入式硬件平台的集成开发软件.该软件适用于DSP、FPGA、CPU等多种不同的硬件平台,提供了统一的模型化开发环境,以代替传统的手工编码开发方式.将该软件应用于创新实验平台,为学生开展创新活动提供了良好的实验环境.%A model-based developing environment software is implemented based on Eclipse RCP framework and Matlab model engine. This software can be used for different kinds of hardware platforms, such as DSP, FPGA and CPU, etc. , and can provide a unified modeling developing environment for hardware platforms, instead of writing source code. This software has been used for innovative experimental platform, providing an excellent experimental environment for college students to conduct innovative experiments.

  8. The Performance Test for Reactor Coolant Pump (RCP) adopting Variable Restriction Orifice Type Control Valve

    Energy Technology Data Exchange (ETDEWEB)

    Kim, S.; Bae, B. U.; Cho, Y. J. and others

    2014-05-15

    The design values of the RCPTF are 17.2 MPa, 343 .deg. C, 11.7 m{sup 3}/s, and 13 MW in the maximum pressure, temperature, flow rate, and electrical power, respectively. In the RCPTF, various types of tests can be performed including a hydraulic performance test to acquire a H-Q curve as well seal transient tests, thrust bearing transient test, cost down test, NPSHR verification test, and so on. After a commissioning startup test was successfully perfomed, mechanical structures are improved including a flow stabilizer and variable restriction orifice. Two- branch pipe (Y-branch) was installed to regulate the flow rate in the range of performance tests. In the main pipe, a flow restrictor (RO: Restriction Orifice) for limiting the maximum flow rate was installed. In the branch pipe line, a globe valve and a butterfly valves for regulating the flow rate was located on the each branch line. When the pressure loss of the valve side is smaller than that of the RO side, the flow rate of valve side was increasing and the flow disturbance was occurred in the lower pipe line. Due to flow disturbnace, it is to cause an error when measuring RCP head and flow measurement of the venturi flow meter installed in the lower main pipe line, and thus leading to a decrease in measurement accuracy as a result. To increase the efficiency of the flow control availability of the test facility, the variable restriction orifice (VRO) type flow control valve was designed and manufactured. In the RCPTF in KAERI, the performance tests and various kinds of transient tests of the RCP were successfully performed. In this study, H-Q curve of the pump using the VRO revealed a similar trend to the result from two ROs. The VRO was confirmed to effectively cover the full test range of the flow rate.

  9. Asymmetry of Surface Climate Change under RCP2.6 Projections from the CMIP5 Models

    Institute of Scientific and Technical Information of China (English)

    XIN Xiaoge; CHENG Yanjie; WANG Fang; WU Tongwen; ZHANG Jie

    2013-01-01

    The multi-model ensemble (MME) of 20 models from the Coupled Model Intercomparison Project Phase Five (CMIP5) was used to analyze surface climate change in the 21st century under the representative concentration pathway RCP2.6,to reflect emission mitigation efforts.The maximum increase of surface air temperature (SAT) is 1.86℃ relative to the pre-industrial level,achieving the target to limit the global warming to 2℃.Associated with the "increase-peak-decline" greenhouse gases (GHGs) concentration pathway of RCP2.6,the global mean SAT of MME shows opposite trends during two time periods:warming during 2006-55 and cooling during 2056-2100.Our results indicate that spatial distribution of the linear trend of SAT during the warming period exhibited asymmetrical features compared to that during the cooling period.The warming during 2006-55 is distributed globally,while the cooling during 2056-2100 mainly occurred in the NH,the South Indian Ocean,and the tropical South Atlantic Ocean.Different dominant roles of heat flux in the two time periods partly explain the asymmetry.During the warming period,the latent heat flux and shortwave radiation both play major roles in heating the surface air.During the cooiing period,the increase of net longwave radiation partly explains the cooling in the tropics and subtropics,which is associated with the decrease of total cloud amount.The decrease of the shortwave radiation accounts for the prominent cooling in the high latitudes of the NH.The surface sensible heat flux,latent heat flux,and shortwave radiation collectively contribute to the especial warming phenomenon in the high-latitude of the SH during the cooling period.

  10. Changes in Temperature Extremes in High Resolution Simulations of RegCM driven by MPI-ESM2 under RCP8.5 and RCP4.5 Scenarios over Turkey

    Science.gov (United States)

    Acar, M.; Ünal, Y. S.

    2015-12-01

    In this study, the effect of climate change on temperature extremes over Turkey is investigated in high resolution climate model simulations driven by a global model outputs. MPI-ESM2 earth system model simulations are downscaled to first 50 km coarse resolution over Med-CORDEX domain and then 10 km high resolution over Turkey by regional climate model, RegCM4.3. The simulations cover the periods of 1970-2000 for the reference and 2015-2100 for the future with proposed changes under Representative Concentration Pathways 4.5 (RCP4.5) and 8.5 (RCP8.5). High resolution gridded surface climate dataset is of great value for the validation phase of the high resolution climate models and the daily temperature observations are interpolated to regular grids which coincide with the simulation's grids by using PRISM (Parameter-elevation Relationships on Independent Slopes Model) approach. High resolution regional climate model performance is evaluated for the reference period by using gridded observations for both averages and extremes of temperature. The RegCM coupled with MPI-ESM2 shows negative biases over most of Turkey. Hence monthly mean value bias correction is applied to temperature simulations of reference and 2015-2100 periods. Extreme temperature climate indices such as FD0, SU25, TX10p, TN10p, TX90p, TN90p, TX35, WSDI, CSDI and DTR are calculated and compared to reference period. Bias corrected high resolution simulations show good agreement with the observations. The climate indices are calculated for the intervals of 2015-2040,2041-2070,2071-2100, for RCP4.5 and RCP8.5 scenarios. FD0, TN10p, TX10p and CSDI indices decrease through the end of century for both scenarios and the most dramatic changes occur on the eastern and central part of Turkey. The rate of decrease is more pronounced in RCP8.5 scenario. On the other hand, the indices of SU25, TX90p, TN90p, TX35 and WSDI increase till 2100. 30 year averages of SU25 and SU35 over all Turkey increase from 64 days

  11. Payment Platform

    DEFF Research Database (Denmark)

    Hjelholt, Morten; Damsgaard, Jan

    2012-01-01

    Payment transactions through the use of physical coins, bank notes or credit cards have for centuries been the standard formats of exchanging money. Recently online and mobile digital payment platforms has entered the stage as contenders to this position and possibly could penetrate societies...... thoroughly and substitute current payment standards in the decades to come. This paper portrays how digital payment platforms evolve in socio-technical niches and how various technological platforms aim for institutional attention in their attempt to challenge earlier platforms and standards. The paper...... applies a co-evolutionary multilevel perspective to model the interplay and processes between technology and society wherein digital payment platforms potentially will substitute other payment platforms just like the credit card negated the check. On this basis this paper formulate a multilevel conceptual...

  12. The implications of carbon dioxide and methane exchange for the heavy mitigation RCP2.6 scenario under two metrics

    NARCIS (Netherlands)

    Huntingford, Chris; Lowe, Jason A.; Howarth, Nicholas; Bowerman, Niel H.A.; Gohar, Laila K.; Otto, Alexander; Lee, David S.; Smith, Stephen M.; den Elzen, Michel G.J.; van Vuuren, Detlef P.; Millar, Richard J.; Allen, Myles R.

    2015-01-01

    Greenhouse gas emissions associated with Representative Concentration Pathway RCP2.6 could limit global warming to around or below a 2°C increase since pre-industrial times. However this scenario implies very large and rapid reductions in both carbon dioxide (CO2) and non-CO2 emissions, and suggests

  13. Can the new RCP R0/R1 classification predict the clinical outcome in ductal adenocarcinoma of the pancreatic head?

    Science.gov (United States)

    Janot, M S; Kersting, S; Belyaev, O; Matuschek, A; Chromik, A M; Suelberg, D; Uhl, W; Tannapfel, A; Bergmann, U

    2012-08-01

    According to the International Union Against Cancer (UICC), R1 is defined as the microscopic presence of tumor cells at the surface of the resection margin (RM). In contrast, the Royal College of Pathologists (RCP) suggested to declare R1 already when tumor cells are found within 1 mm of the RM. The aim of this study was to determine the significance of the RM concerning the prognosis of pancreatic ductal adenocarcinoma (PDAC). From 2007 to 2009, 62 patients underwent a curative operation for PDAC of the pancreatic head. The relevance of R status on cumulative overall survival (OS) was assessed on univariate and multivariate analysis for both the classic R classification (UICC) and the suggestion of the RCP. Following the UICC criteria, a positive RM was detected in 8 %. Along with grading and lymph node ratio, R status revealed a significant impact on OS on univariate and multivariate analysis. Applying the suggestion of the RCP, R1 rate rose to 26 % resulting in no significant impact on OS in univariate analysis. Our study has shown that the RCP suggestion for R status has no impact on the prognosis of PDAC. In contrast, our data confirmed the UICC R classification of RM as well as N category, grading, and lymph node ratio as significant prognostic factors.

  14. The implications of carbon dioxide and methane exchange for the heavy mitigation RCP2.6 scenario under two metrics

    NARCIS (Netherlands)

    Huntingford, Chris; Lowe, Jason A.; Howarth, Nicholas; Bowerman, Niel H.A.; Gohar, Laila K.; Otto, Alexander; Lee, David S.; Smith, Stephen M.; den Elzen, Michel G.J.; van Vuuren, Detlef P.; Millar, Richard J.; Allen, Myles R.

    2015-01-01

    Greenhouse gas emissions associated with Representative Concentration Pathway RCP2.6 could limit global warming to around or below a 2°C increase since pre-industrial times. However this scenario implies very large and rapid reductions in both carbon dioxide (CO2) and non-CO2 emissions, and suggests

  15. The Framework and Mode of Cloud Manufacturing Public Service Platform for Regional Industry Clusters%面向区域产业集群的云制造服务平台架构与模式研究

    Institute of Scientific and Technical Information of China (English)

    盛磊; 林宏权; 刘继红

    2012-01-01

    为了提高我国东部沿海中小企业集聚地区从“块状经济”向现代产业集群转型过程中的创新、协同和服务的能力,结合云制造和服务型制造的理念,提出了建设面向区域产业集群的云制造公共服务平台的解决方案,建立了面向区域产业集群的云制造公共服务平台的体系架构,研究了一种依托行业核心龙头企业的区域多中心运营模式及相应的服务模式方案,为进一步深入与系统地开展面向区域产业集群的云制造公共服务平台的研究、开发和应用实施提供了基础.%In order to improve the innovation, collaboration, and service ability of the eastern coastal small and medium - 9ized enterprises cluster region during the transformation from a " massive economy" to a modern industry cluster, re-ferring to cloud manufacturing and service - oriented manufacturing concept, this paper proposes a solution to construct a cloud manufacturing public service platform for the regional industry cluster. The framework of the cloud manufacturing public service platform for the regional industry cluster is established- A leading - enterprises - dependent operation mode with multiple regional centers is addressed. And the corresponding implementation scheme is explored. This research can provide reference for the further and systematic research, development, and implementation of the regional industry clus-ters' cloud manufacturing public platform.

  16. Metal-organic-framework-based tandem molecular sieves as a dual platform for selective microextraction and high-resolution gas chromatographic separation of n-alkanes in complex matrixes.

    Science.gov (United States)

    Chang, Na; Gu, Zhi-Yuan; Wang, He-Fang; Yan, Xiu-Ping

    2011-09-15

    Metal-organic frameworks (MOFs) were employed to design tandem molecular sieves as a dual platform for selective solid-phase microextraction (SPME) and high-resolution gas chromatographic (GC) separation of target analytes in complex matrixes. An elegant combination of a ZIF-8-coated fiber for SPME with a ZIF-8-coated capillary for GC allows selective extraction and separation of n-alkanes from complex matrixes such as petroleum-based fuel and biological fluids. The proposed tandem ZIF-8 molecular sieves not only offered good enhancement factors from 235 (hexane) to 1212 (nonane), but also exhibited wide linearity with 3 orders of magnitude for the tested linear alkanes. The limits of detection for the linear alkanes ranged from 0.46 ng L(-1) (nonane) to 1.06 ng L(-1)(hexane). The relative standard deviations of retention time, peak area, peak height, and half peak width for five replicate determinations of the tested n-alkanes at 30 ng L(-1) were 0.02-0.26%, 1.9-8.6%, 1.4-6.0%, and 1.3-7.2%, respectively. The developed tandem ZIF-8 molecular sieves were further used for the determination of linear alkanes in petroleum-based fuel and human serum. The large diversity in structure and pore size allows various combinations of MOFs for designing an MOF-based tandem molecular sieve platform to achieve different selectivities in extraction and chromatographic separation and to solve headache problems in complex real sample analysis.

  17. A new framework for quantifying uncertainties in modelling studies for future climates - how more certain are CMIP5 precipitation and temperature simulations compared to CMIP3?

    Science.gov (United States)

    Sharma, A.; Woldemeskel, F. M.; Sivakumar, B.; Mehrotra, R.

    2014-12-01

    We outline a new framework for assessing uncertainties in model simulations, be they hydro-ecological simulations for known scenarios, or climate simulations for assumed scenarios representing the future. This framework is illustrated here using GCM projections for future climates for hydrologically relevant variables (precipitation and temperature), with the uncertainty segregated into three dominant components - model uncertainty, scenario uncertainty (representing greenhouse gas emission scenarios), and ensemble uncertainty (representing uncertain initial conditions and states). A novel uncertainty metric, the Square Root Error Variance (SREV), is used to quantify the uncertainties involved. The SREV requires: (1) Interpolating raw and corrected GCM outputs to a common grid; (2) Converting these to percentiles; (3) Estimating SREV for model, scenario, initial condition and total uncertainty at each percentile; and (4) Transforming SREV to a time series. The outcome is a spatially varying series of SREVs associated with each model that can be used to assess how uncertain the system is at each simulated point or time. This framework, while illustrated in a climate change context, is completely applicable for assessment of uncertainties any modelling framework may be subject to. The proposed method is applied to monthly precipitation and temperature from 6 CMIP3 and 13 CMIP5 GCMs across the world. For CMIP3, B1, A1B and A2 scenarios whereas for CMIP5, RCP2.6, RCP4.5 and RCP8.5 representing low, medium and high emissions are considered. For both CMIP3 and CMIP5, model structure is the largest source of uncertainty, which reduces significantly after correcting for biases. Scenario uncertainly increases, especially for temperature, in future due to divergence of the three emission scenarios analysed. While CMIP5 precipitation simulations exhibit a small reduction in total uncertainty over CMIP3, there is almost no reduction observed for temperature projections

  18. Water Vapor Measurements by Mobile Raman Lidar Over The Mediterranean Sea in the Framework of HyMex: Application to Multi-Platform Validation of Moisture Profiles

    Directory of Open Access Journals (Sweden)

    Totems Julien

    2016-01-01

    Full Text Available The Water Aerosol Lidar (WALI system, deployed for 14 weeks during 2012 & 2013 on the island of Menorca, provided the Hydrological cycle in the Mediterranean eXperiment (HyMeX with an opportunity to perform a multi-platform comparison on moisture retrievals at the timescales relevant for extreme precipitation events in the West Mediterranean basin. After calibration, the WALI lidar yields nighttime profiles of water vapor with ~7% accuracy from the ground up to 7 km, and daytime coverage of the lower layers, alongside common aerosol retrievals. It is used to characterize the water vapor profile product given by the IASI instrument on-board MetOp-B, and the fields simulated by the Météo-France AROME-WMED model and the open-source WRF model. IASI is found to be reliable above 1 km altitude, and the two models obtain similar high scores in the middle troposphere; WRF beneficiates from a more accurate modelling of the planetary boundary layer.

  19. Design of Performance Appraisal System Based on Open Source Framework and Platform%基于开源框架和平台的绩效考核系统设计

    Institute of Scientific and Technical Information of China (English)

    梁佃

    2014-01-01

    [目的]针对企业或机关单位需要利用信息化进行绩效考核的需求,研究低成本的绩效考核系统。[方法]使用跨平台的开发语言JAVA进行编程,利用开源免费的轻量级框架快速构建基于MVC架构的系统平台,再利用开源免费的操作系统、中间件和数据库搭建Web服务器,并结合局域网构建实现交互式的网络应用软件系统。[结果]该系统设计简便,且能实现跨平台操作。[结论]基于开源框架和平台的开发模式,可在低成本的前提下,最大限度地提高软件产品的质量和开发效率。%[Objective]This paper proposes a secure and reliable low-cost solution to information-based performance appraisal for enterprises and institutions.[Method]Cross platform development language JAVA programming and lightweight framework of free open source is used to rapid construct MVC-based system platform. Operating system of free open source and middleware and database building Web server, combined with the local area network is used to construct software system for implementation B/S-based interactive network application.[Result]Based on the design process and key technology, performance appraisal for enterprises and institutions is achieved.[Conclusion]The results show that the development model based on the open source framework and platform provides a low cost method for the improvement of software quality and development efficiency.

  20. Zirconium-metalloporphyrin frameworks as a three-in-one platform possessing oxygen nanocage, electron media, and bonding site for electrochemiluminescence protein kinase activity assay

    Science.gov (United States)

    Zhang, Guang-Yao; Cai, Chang; Cosnier, Serge; Zeng, Hai-Bo; Zhang, Xue-Ji; Shan, Dan

    2016-06-01

    A Zr-based metal-organic framework with zinc tetrakis(carboxyphenyl)-porphyrin (ZnTCPP) groups (MOF-525-Zn) was utilized to develop a novel electrochemiluminescence (ECL) biosensor for highly sensitive protein kinase activity assay. In this work, in terms of ECL measurements and cyclic voltammetry, the cathodic ECL behaviors of MOF-525-Zn in aqueous media were thoroughly investigated for the first time. The photoelectric active groups ZnTCPP on the MOF-525-Zn frameworks could promote the generation of singlet oxygen (1O2) via a series of electrochemical and chemical reactions, resulting in a strong and stable red irradiation at 634 nm. Additionally, the surfactant tetraoctylammonium bromide (TOAB) further facilitated dissolved oxygen to interact with the active sites ZnTCPP of MOF-525-Zn. Furthermore, the inorganic Zr-O clusters of MOF-525-Zn were simultaneously served as the recognition sites of phosphate groups. And then, an ultrasensitive ECL sensor was proposed for protein kinase A (PKA) activity detection with a linear range from 0.01 to 20 U mL-1 and a sensitive detection limit of 0.005 U mL-1. This biosensor can also be applied for quantitative kinase inhibitor screening. Finally, it exhibits good performance with high stability and acceptable fabrication reproducibility, which provide a valuable strategy for clinic diagnostics and therapeutics.A Zr-based metal-organic framework with zinc tetrakis(carboxyphenyl)-porphyrin (ZnTCPP) groups (MOF-525-Zn) was utilized to develop a novel electrochemiluminescence (ECL) biosensor for highly sensitive protein kinase activity assay. In this work, in terms of ECL measurements and cyclic voltammetry, the cathodic ECL behaviors of MOF-525-Zn in aqueous media were thoroughly investigated for the first time. The photoelectric active groups ZnTCPP on the MOF-525-Zn frameworks could promote the generation of singlet oxygen (1O2) via a series of electrochemical and chemical reactions, resulting in a strong and stable red

  1. Universal visualization platform

    Science.gov (United States)

    Gee, Alexander G.; Li, Hongli; Yu, Min; Smrtic, Mary Beth; Cvek, Urska; Goodell, Howie; Gupta, Vivek; Lawrence, Christine; Zhou, Jainping; Chiang, Chih-Hung; Grinstein, Georges G.

    2005-03-01

    Although there are a number of visualization systems to choose from when analyzing data, only a few of these allow for the integration of other visualization and analysis techniques. There are even fewer visualization toolkits and frameworks from which one can develop ones own visualization applications. Even within the research community, scientists either use what they can from the available tools or start from scratch to define a program in which they are able to develop new or modified visualization techniques and analysis algorithms. Presented here is a new general-purpose platform for constructing numerous visualization and analysis applications. The focus of this system is the design and experimentation of new techniques, and where the sharing of and integration with other tools becomes second nature. Moreover, this platform supports multiple large data sets, and the recording and visualizing of user sessions. Here we introduce the Universal Visualization Platform (UVP) as a modern data visualization and analysis system.

  2. 基于大数据的云物流管理平台的架构设计%Framework Design of Cloud Logistics Management Platform Based on Big Data

    Institute of Scientific and Technical Information of China (English)

    温荷

    2015-01-01

    分析了物流管理系统现状,结合大数据、云计算技术为物流行业带来的创新思维,构建了一个基于大数据的云物流管理平台,为智能物流搭建了一个统一的标准架构,并对应用模块的大数据分析提出了功能见解.%In this paper, we analyzed the current status of the logistics management system, then in view of the innovative ideas brought to the logistics industry by the big data and cloud computation technologies, established a cloud logistics management platform based on big data, set up a uniform framework for the smart logistics businesses, and at the end, gave our opinions on the role of the big data in the various modules of the framework.

  3. Video analysis platform

    OpenAIRE

    FLORES, Pablo; Arias, Pablo; Lecumberry, Federico; Pardo, Álvaro

    2006-01-01

    In this article we present the Video Analysis Platform (VAP) which is an open source software framework for video analysis, processing and description. The main goals of VAP are: to provide a multiplatform system which allows the easy implementation of video algorithms, provide structures and algorithms for the segmentation of video data in its different levels of abstraction: shots, frames, objects, regions, etc, permit the generation and comparison of MPEG7-like descriptors, and develop tes...

  4. Platform development: implications for portfolio management

    DEFF Research Database (Denmark)

    Hsuan, Juliana; Hansen, Poul H. Kyvsgård

    2007-01-01

    complex, possibly increasing the strategic risks for the firm. This paper reports preliminary findings on platform management process at LEGO, a Danish toy company. Specifically, we report the process of applying games combined with simulations and workshops in the platform development. We also propose...... a framework, based on the portfolio management thinking to evaluate the degree of modularity embedded in a given platform and to which extent it is aligned with other platforms."...

  5. Future Climate Data from RCP 4.5 and Occurrence of Malaria in Korea

    Directory of Open Access Journals (Sweden)

    Jaewon Kwak

    2014-10-01

    Full Text Available Since its reappearance at the Military Demarcation Line in 1993, malaria has been occurring annually in Korea. Malaria is regarded as a third grade nationally notifiable disease susceptible to climate change. The objective of this study is to quantify the effect of climatic factors on the occurrence of malaria in Korea and construct a malaria occurrence model for predicting the future trend of malaria under the influence of climate change. Using data from 2001–2011, the effect of time lag between malaria occurrence and mean temperature, relative humidity and total precipitation was investigated using spectral analysis. Also, a principal component regression model was constructed, considering multicollinearity. Future climate data, generated from RCP 4.5 climate change scenario and CNCM3 climate model, was applied to the constructed regression model to simulate future malaria occurrence and analyze the trend of occurrence. Results show an increase in the occurrence of malaria and the shortening of annual time of occurrence in the future.

  6. [Lens platform].

    Science.gov (United States)

    Łukaszewska-Smyk, Agnieszka; Kałuzny, Józef

    2010-01-01

    The lens platform defines lens structure and lens material. Evolution of lens comprises change in their shape, angulation of haptens and transition of three-piece lens into one-piece lens. The lens fall into two categories: rigid (PMMA) and soft (siliconic, acrylic, colameric). The main lens maaterials are polymers (hydrophilic and hydrophobic). The lens platform has an effect on biocompatibility, bioadhesion, stability of lens in capsule, degree of PCO evolution and sensitiveness to laser damages.

  7. Platform contents

    OpenAIRE

    Renault, Régis

    2014-01-01

    A monopoly platform hosts advertisers who compete on a market for horizontally differentiated products. These products may be either mass market products that appeal broadly to the entire consumer population or niche products that are tailored to the tastes of some particular group. Consumers search sequentially through ads incurring a surfing cost of moving to the next ad. They may click on an ad at some cost, which provides all relevant information and the opportunity to buy. The platform c...

  8. 面向企业私有云计算平台的安全构架研究%Research on security framework of enterprise private cloud computing platform

    Institute of Scientific and Technical Information of China (English)

    刘胜娃; 陈思锦; 李卫; 高翔

    2014-01-01

    Cloud computing is an Internet-based emerging application of computer technology. Private cloud is a basic sup-port for setting up the cloud management system in the internal of enterprise private datacenter. It provides a platform of compu-tation,storage and network resource management and control for definition and running of cloud. The enterprise private cloud construction plan is discussed in this paper. The enterprise private cloud construction content,goal and benefit are analyzed. this paper also analyzes The further analysis on security problems of cloud platform are conducted. A security framework for dealing with this problem is proposed. A reference for the enterprise private cloud construction is presented in this paper.%云计算是一种基于互联网的新兴应用计算机技术。私有云是在企业自有数据中心内部搭建云管理环境系统的基础支撑,为定义、运行云应用提供计算、存储和网络资源管控平台。对企业私有云建设方案进行了探讨,介绍和分析了企业私有云建设内容、目标及效益分析,并进一步分析了私有云所面临的安全问题,提出了私有云的安全框架,为企业私有云建设提供参考。

  9. Projected and Observed Aridity and Climate Change in the East Coast of South India under RCP 4.5.

    Science.gov (United States)

    Ramachandran, A; Praveen, Dhanya; Jaganathan, R; Palanivelu, K

    2015-01-01

    In the purview of global warming, the present study attempts to project changes in climate and quantify the changes in aridity of two coastal districts in south India under the RCP 4.5 trajectory. Projected climate change output generated by RegCM 4.4 model, pertaining to 14 grid points located within the study area, was analyzed and processed for this purpose. The meteorological parameters temperature and precipitations were used to create De Martonne Aridity Index, to assess the spatial distribution of aridity. The original index values ranged from 13.7 to 16.4 mm/°C, characterizing this area as a semidry climate. The outcome from the changed scenario analysis under RCP 4.5 showed that, during the end of the 21st century, the aridity may be increased more as the index values tend to reduce. The increasing trend in the drying phenomenon may be attributed to the rising of mean annual temperatures.

  10. ICT based Sustainable Rural Business Opportunities in Developing Countries: A Wireless-Networked RCP-RAP Approach

    Directory of Open Access Journals (Sweden)

    Md. A. Rahman

    2005-01-01

    Full Text Available Information and Communication Technology (ICT is gaining much research attention in present times especially for its ability towards poverty alleviation. In this study the prospect of rural business opportunities in developing countries more specifically in the target country, Bangladesh, has been investigated from the viewpoint of wirelessly networked Rural Communication Point (RCP approach. It is proposed that if only one RCP is set up in every village and there is one Regional Access Point (RAP responsible for several wirelessly networked RCPs, it is recommended that a significant development is possible in rural areas of the target country with the assistance from existing ICT infrastructure. In this study, the target country is chosen as Bangladesh in South Asia but the similar ICT model can be implemented with success in other countries in the developing world.

  11. Stability analysis of a max-min fair Rate Control Protocol (RCP) in a small buffer regime

    CERN Document Server

    Voice, Thomas

    2007-01-01

    In this note we analyse various stability properties of the max-min fair Rate Control Protocol (RCP) operating with small buffers. We first tackle the issue of stability for networks with arbitrary topologies. We prove that the max-min fair RCP fluid model is globally stable in the absence of propagation delays, and also derive a set of conditions for local stability when arbitrary heterogeneous propagation delays are present. The network delay stability result assumes that, at equilibrium, there is only one bottleneck link along each route. Lastly, in the simpler setting of a single link, single delay model, we investigate the impact of the loss of local stability via a Hopf bifurcation.

  12. A probabilistic approach to 21st century regional sea-level projections using RCP and High-end scenarios

    Science.gov (United States)

    Jackson, Luke P.; Jevrejeva, Svetlana

    2016-11-01

    Sea-level change is an integrated climate system response due to changes in radiative forcing, anthropogenic land-water use and land-motion. Projecting sea-level at a global and regional scale requires a subset of projections - one for each sea-level component given a particular climate-change scenario. We construct relative sea-level projections through the 21st century for RCP 4.5, RCP 8.5 and High-end (RCP 8.5 with increased ice-sheet contribution) scenarios by aggregating spatial projections of individual sea-level components in a probabilistic manner. Most of the global oceans adhere to the projected global average sea level change within 5 cm throughout the century for all scenarios; however coastal regions experience localised effects due to the non-uniform spatial patterns of individual components. This can result in local projections that are 10‧s of centimetres different from the global average by 2100. Early in the century, RSL projections are consistent across all scenarios, however from the middle of the century the patterns of RSL for RCP scenarios deviate from the High-end where the contribution from Antarctica dominates. Similarly, the uncertainty in projected sea-level is dominated by an uncertain Antarctic fate. We also explore the effect upon projections of, treating CMIP5 model ensembles as normally distributed when they might not be, correcting CMIP5 model output for internal variability using different polynomials and using different unloading patterns of ice for the Greenland and Antarctic ice sheets.

  13. 基于云计算的煤矿物联网一体化平台体系架构%Integrated Platform System Framework of Mine Internet of Things Based on Cloud Computation

    Institute of Scientific and Technical Information of China (English)

    裴忠民; 李波; 徐硕; 朱华

    2012-01-01

    在总结煤矿安全生产管理信息系统发展历程的基础上,着眼于物联网、云计算等技术在煤矿领域的应用发展,提出了煤矿物联网一体化信息平台的概念,并对其特征进行了详细阐述;基于分层设计理念,给出了包含感知层、通信传输层、信息服务层和应用层4层结构的煤矿物联网一体化信息平台体系架构,介绍了每层结构的功能和组成。在此基础上,重点阐述了构建煤矿物联网一体化信息平台所涉及的现场感知与自组网、短距离无线通信、智能信息处理与服务、防爆设计等关键技术问题。%Based on the summarization of the development experiences in the mine safety production and management information system, looking at the application development of the internet of things, the cloud computation and other technology to the coal mines, an integrat-ed information platform conception of the mine internet of things was provided and the features were stated in detail. Based on the slicing design eonception, the integrated information platform system framework of the mine internet of things including the perception layer, com- munication and transmission layer, information services layer and application layer structures was provided. The paper introduced the function and composition of the each structure. Base the circumstances, the paper stressed the site perception and self organized network, short distance wireless communication, intelligent information processing and services, flame proof design and other key technical prob-lems related to the establishment on the integrated information platform of the mine internet of things.

  14. 基于整合框架的Web应用系统开发平台设计与实现%Design and implementation of development platform for Web application systems based on integrated framework

    Institute of Scientific and Technical Information of China (English)

    林钰杰; 吴丽贤

    2016-01-01

    面对日益复杂的Web应用系统和变更频繁的用户需求,企业需要从纷繁复杂的开发框架中选出一套可行的解决方案以保持高效保质的开发工作,为此,本文采用J2EE分层架构思想构建了一个面向Web应用系统快速开发的开发平台,其中,平台表现层采用Ember.js对JSP局部页面进行异步刷新,控制层由Spring MVC实现,业务层以Spring Framework为基础集成Activiti流程引擎和Velocity模板引擎,持久层由JPA负责完成与数据库的交互。实践证明,采用该开发平台构建的Web应用系统均具有层次间耦合度低、模块复用性高等特点,大大提高了开发的效率,有效降低了开发和维护的成本。%In the face of increasingly complex Web application systems and frequently changed user requirements, the enterprises need to choose a feasible solution form numerous and complicated development frameworks so as to maintain high efficiency and quality of development work. For this purpose, this paper constructs a development platform for rapid development of Web application systems based on J2EE layered architecture. In presentation layer, Ember.js is implemented asynchronous refresh on partial page of JSP. In control layer, it is achieved with Spring MVC. In business layer, Activiti process engine and Velocity template engine are integrated on the basis of Spring Framework. In persistence layer, JPA is adopted to implement interactive with databases. It has been proved that the Web application systems constructed form the development platform have the characteristics of low coupling degree between layers and high reusability for modules, which improve the development efficiency and reduce the cost of development and maintenance greatly.

  15. Changes to extreme wave climates of islands within the Western Tropical Pacific throughout the 21st century under RCP 4.5 and RCP 8.5, with implications for island vulnerability and sustainability

    Science.gov (United States)

    Shope, James B.; Storlazzi, Curt D.; Erikson, Li H.; Hegermiller, Christie A.

    2016-06-01

    Waves are the dominant influence on coastal morphology and ecosystem structure of tropical Pacific islands. Wave heights, periods, and directions for the 21st century were projected using near-surface wind fields from four atmosphere-ocean coupled global climate models (GCM) under representative concentration pathways (RCP) 4.5 and 8.5. GCM-derived wind fields forced the global WAVEWATCH-III wave model to generate hourly time series of bulk wave parameters around 25 islands in the mid to western tropical Pacific Ocean for historical (1976-2005), mid-century, and end-century time periods for the December-February and June-August seasons. The December-February regional wave climate is dominated by strong winds and large swell from extratropical cyclones in the north Pacific while the June-August season brings smaller waves generated by the trade winds and swell from Southern Hemisphere extratropical storms. Extreme significant wave heights decreased ( 10.0%) throughout the 21st century under both climate scenarios compared to historical wave conditions and the higher radiative forcing RCP 8.5 scenario displayed a greater and more widespread decrease in extreme significant wave heights compared to the lower forcing RCP 4.5 scenario. An exception was for the end-century June-August season. Offshore of islands in the central equatorial Pacific, extreme significant wave heights displayed the largest changes from historical values. The frequency of extreme events during December-February decreased under RCP 8.5, whereas the frequency increased under RCP 4.5. Mean wave directions rotated more than 30° clockwise at several locations during June-August, which could indicate a weakening of the trade winds' influence on extreme wave directions and increasing dominance of Southern Ocean swell. The results of this study underscore that December-February large wave events will become smaller and less frequent in most regions, reducing the likelihood and magnitude of wave

  16. Future changes in atmospheric condition for the baiu under RCP scenarios

    Science.gov (United States)

    Okada, Y.; Takemi, T.; Ishikawa, H.

    2015-12-01

    This study focuses on atmospheric circulation fields during the baiu in Japan with global warming projection experimental data conducted using a 20-km mesh global atmospheric model (MRI-AGCM3.2) under Representative Concentration Pathways (RCP) scenarios. This model also used 4 different sea surface temperature (SST) initial conditions. Support of this dataset is provided by the Meteorological Research Institute (MRI). The baiu front indicated by the north-south gradient of moist static energy moves northward in present-day climate, whereas this northward shift in future climate simulations is very slow during May and June. In future late baiu season, the baiu front stays in the northern part of Japan even in August. As a result, the rich water vapor is transported around western Japan and the daily precipitation amount will increase in August. This northward shift of baiu front is associated with the westward expansion of the enhanced the North Pacific subtropical high (NPSH) into Japan region. However, the convective activity around northwest Pacific Ocean is inactive and is unlikely to occur convective jump (CJ). These models show that the weak trough exists in upper troposphere around Japan. Therefore, the cold advection stays in the northern part of Japan during June. In July, the front due to the strengthening of the NPSH moves northward, and then it stays until August. This feature is often found between the clustered SSTs, Cluster 2 and 3. The mean field of future August also show the inflow of rich water vapor content to Japan islands. In this model, the extreme rainfall suggested tends to almost increase over the Japan islands during future summer. This work was conducted under the Program for Risk Information on Climate Change supported by the Ministry of Education, Culture, Sports, Science, and Technology-Japan (MEXT).

  17. Changes of precipitation extremes over South Korea projected by the 5 RCMs under RCP scenarios

    Science.gov (United States)

    Ahn, Joong-Bae; Jo, Sera; Suh, Myoung-Seok; Cha, Dong-Hyun; Lee, Dong-Kyou; Hong, Song-You; Min, Seung-Ki; Park, Seong-Chan; Kang, Hyun-Suk; Shim, Kyo-Moon

    2016-05-01

    The change of extreme precipitation is assessed with the HadGEM2-AO - 5 Regional Climate Models (RCMs) chain, which is a national downscaling project undertaken cooperatively by several South Korean institutes aimed at producing regional climate change projection with fine resolution (12.5 km) around the Korean Peninsula. The downscaling domain, resolution and lateral boundary conditions are held the same among the 5 RCMs to minimize the uncertainties from model configuration. Climatological changes reveal a statistically significant increase in the mid-21st century (2046- 2070; Fut1) and the late-21st century (2076-2100; Fut2) precipitation properties related to extreme precipitation, such as precipitation intensity and average of upper 5 percentile daily precipitation, with respect to the reference period (1981-2005). Changes depending on the intensity categories also present a clear trend of decreasing light rain and increasing heavy rain. In accordance with these results, the change of 1-in-50 year maximum precipitation intensity over South Korea is estimated by the GEV method. The result suggests that the 50-year return value (RV50) will change from -32.69% to 72.7% and from -31.6% to 96.32% in Fut1 and from -31.97% to 86.25% and from -19.45% to 134.88% in Fut2 under representative concentration pathway (RCP) 4.5 and 8.5 scenarios, respectively, at the 90% confidence level. This study suggests that multi-RCMs can be used to reduce uncertainties and assess the future change of extreme precipitation more reliably. Moreover, future projection of the regional climate change contains uncertainties evoked from not only driving GCM but also RCM. Therefore, multi-GCM and multi-RCM studies are expected to provide more robust projection.

  18. ITS Platform

    DEFF Research Database (Denmark)

    Tøfting, Svend; Lahrmann, Harry; Agerholm, Niels

    2014-01-01

    Aalborg University and two local companies have over the past four years developed and tested an ITS Platform, which can be used for communication with cars and for providing a number of services to the drivers. The purpose has been to perform a technological test of the possible use of a hidden ...... not have to be very intelligent. This is gradually taken over by applications on smart phones. The ITS Platform with 425 test drivers is now completely developed and can be used for technological testing of e.g. payment systems.......Aalborg University and two local companies have over the past four years developed and tested an ITS Platform, which can be used for communication with cars and for providing a number of services to the drivers. The purpose has been to perform a technological test of the possible use of a hidden...

  19. ITS Platform

    DEFF Research Database (Denmark)

    Tøfting, Svend; Lahrmann, Harry; Agerholm, Niels

    2014-01-01

    Aalborg University and two local companies have over the past four years developed and tested an ITS Platform, which can be used for communication with cars and for providing a number of services to the drivers. The purpose has been to perform a technological test of the possible use of a hidden ...... not have to be very intelligent. This is gradually taken over by applications on smart phones. The ITS Platform with 425 test drivers is now completely developed and can be used for technological testing of e.g. payment systems....

  20. Geo-spatial Framework Data System in Platform of Geographic Information Service%面向在线服务的地理框架数据体系构建

    Institute of Scientific and Technical Information of China (English)

    黄蔚; 蒋捷; 王茜

    2011-01-01

    分析了在线服务对地理信息的需求,阐述了面向在线服务的地理框架数据体系构建技术实现方法,设计了适应多源数据协同服务的数据集成方式和满足多样化应用需求的地理框架数据内容构成与建模方法,并说明了其在国家地理信息公共服务平台公众版“天地图”中的应用.%Based on the analysis of online service requirements for geo-spatial data, the paper proposes the method of constructing geo-spatial framework data system for online spatial data service. How to integrate multi -sources data and develop multi -types data products suitable for collaborative online services and diverse applications are described. The method is verified in the construction of National Geo-spalial Information Service Platform.

  1. Platform computing

    CERN Multimedia

    2002-01-01

    "Platform Computing releases first grid-enabled workload management solution for IBM eServer Intel and UNIX high performance computing clusters. This Out-of-the-box solution maximizes the performance and capability of applications on IBM HPC clusters" (1/2 page) .

  2. Changes to extreme wave climates of islands within the Western Tropical Pacific throughout the 21st century under RCP 4.5 and RCP 8.5, with implications for island vulnerability and sustainability

    Science.gov (United States)

    Shope, James B.; Storlazzi, Curt; Erikson, Li; Hegermiller, Christie

    2016-01-01

    Waves are the dominant influence on coastal morphology and ecosystem structure of tropical Pacific islands. Wave heights, periods, and directions for the 21st century were projected using near-surface wind fields from four atmosphere-ocean coupled global climate models (GCM) under representative concentration pathways (RCP) 4.5 and 8.5. GCM-derived wind fields forced the global WAVEWATCH-III wave model to generate hourly time-series of bulk wave parameters around 25 islands in the mid to western tropical Pacific Ocean for historical (1976–2005), mid-, and end-of-century time periods. Extreme significant wave heights decreased (~10.0%) throughout the 21st century under both climate scenarios compared to historical wave conditions and the higher radiative forcing 8.5 scenario displayed a greater and more widespread decrease in extreme significant wave heights compared to the lower forcing 4.5 scenario. An exception was for the end-of-century June–August season. Offshore of islands in the central equatorial Pacific, extreme significant wave heights displayed the largest changes from historical values. The frequency of extreme events during December–February decreased under RCP 8.5, whereas the frequency increased under RCP 4.5. Mean wave directions often rotated more than 30° clockwise at several locations during June–August, which could indicate a weakening of the trade winds’ influence on extreme wave directions and increasing dominance of Southern Ocean swell or eastern shift of storm tracks. The projected changes in extreme wave heights, directions of extreme events, and frequencies at which extreme events occur will likely result in changes to the morphology and sustainability of island nations.

  3. A Framework for Assessing Soil Moisture Deficit and Crop Water Stress at Multiple Space and Time Scales Under Climate Change Scenarios Using Model Platform, Satellite Remote Sensing, and Decision Support System

    KAUST Repository

    Mohanty, Binayak P.

    2016-11-03

    Better understanding of water cycle at different space–time scales would be a key for sustainable water resources, agricultural production, and ecosystems health in the twenty-first century. Efficient agricultural water management is necessary for sustainability of the growing global population. This warrants better predictive tools for aridity (based on precipitation, temperature, land use, and land cover), root zone (~top 1 m) soil moisture deficit, and crop water stress at farm, county, state, region, and national level, where decisions are made to allocate and manage the water resources. It will provide useful strategies for not only efficient water use but also for reducing potential risk of crop failure due to agricultural drought. Leveraging heavily on ongoing multiscale hydrologic modeling, data assimilation, soil moisture dynamics, and inverse model development research activities, and ongoing Land Data Assimilation (LDAS) and National Climate Assessment (NCA) indexing efforts we are developing a drought assessment framework. The drought assessment platform includes: (1) developing disaggregation methods for extracting various field-scale (1-km or less) climate indicators from the (SMOS, VIIRS, SMAP, AMSR-2) satellite / LDAS-based soil moisture in conjunction with a multimodel simulation–optimization approach using ensemble of Soil Vegetation Atmosphere Transfer, SVAT (Noah, CLM, VIC, Mosaic in LIS) models; (2) predicting farm/field-scale long-term root zone soil moisture status under various land management and climate scenarios for the past decades in hindcast mode and for the next decades in forecast mode across the USA using effective land surface parameters and meteorological input from Global Circulation Model (GCM) outputs; (3) assessing the potential risk of agricultural drought at different space–time scales across the USA based on predicted root zone soil moisture; and (4) evaluating various water management and cropping practices (e

  4. Platform independent software framework for smartphones

    OpenAIRE

    Žemaitis, Tomas

    2010-01-01

    Šiomis dienomis labai greitai tobulėja mobilios technologijos. Į išmaniuosius įrenginius montuojamų procesorių taktinis dažnis jau pasiekė 1Ghz, ekranai tapo labai didelės raiškos, jautrūs lietimui bei pasižymintys labai kokybišku spalvų atkūrimu. Dėl daugybės į išmaniuosius telefonus montuojamų papildomų įtaisų, jų panaudojimo sritis vis plečiasi, jų populiarumas auga. Kartu su aparatūros tobulėjimu, tobulėja ir jiems skirta programinė įranga. Per paskutinius kelis metus pasirodė net trys na...

  5. 网络教学集成平台的功能框架与功能分析%Functional framework and functional analysis on network teaching integrated platform

    Institute of Scientific and Technical Information of China (English)

    王洪敏

    2014-01-01

    网络教学是现代教育技术在教学过程中的具体应用,网络教学平台是实施网络教学的技术基础和载体,是体现网络教育优势的关键因素。针对软件开发过程中系统功能难以确定的问题,本文以功能框架为基础对各个功能进行具体分析。功能框架部分通过6大功能及24个子功能构成的层次结构图表示,功能分析部分对教学组织、在线交流、在线考核、教学资源、系统维护等模块及其子模拟进行了详细分析。通过本文设计的各个模块可以自由组装,为软件开发奠定了基础。%Network teaching is the specific application of modern educational technology in the teaching process, network teaching platform is the technology base and the carrier of the implementation of the network teaching, and it is the key factor to reflect the advantages of network education. For the problems that system functionality is difficult to determine in the software development process, this article based on the functional framework specific analyzed various functions. Functional framework parts through the hierarchy diagrams consisting of the six major functional and 24 sub-function to express, functional analysis parts on teaching organization, online communication, online assessment, teaching resources, system maintenance modules and its sub-simulation carried out detailed analysis. Through each module is designed in this paper can be assembled freely, laid the foundation for software development.

  6. Platform Expansion Design as Strategic Choice

    DEFF Research Database (Denmark)

    Staykova, Kalina S.; Damsgaard, Jan

    2016-01-01

    the main characteristics of the two approaches and to identify the potential trade-offs associated with the selection of particular expansion mode. To this end, we construct the Platform Strategy Framework and apply it to two exemplary cases – WeChat, which functions as a feature bundling platform...

  7. Platform Expansion Design as Strategic Choice

    DEFF Research Database (Denmark)

    Staykova, Kalina S.; Damsgaard, Jan

    2016-01-01

    the main characteristics of the two approaches and to identify the potential trade-offs associated with the selection of particular expansion mode. To this end, we construct the Platform Strategy Framework and apply it to two exemplary cases – WeChat, which functions as a feature bundling platform...

  8. The Rab11-FIP1/RCP gene codes for multiple protein transcripts related to the plasma membrane recycling system.

    Science.gov (United States)

    Jin, Min; Goldenring, James R

    2006-06-01

    Rab11a is a member of the Rab11 small GTPase family, and plays an important role in plasma membrane recycling. Rab11-Family Interacting Protein 1 (Rab11-FIP1) binds to Rab11 through a carboxyl-terminal amphipathic alpha helix. We have identified eight alternatively spliced Rab11-FIP1 gene transcripts from human chromosome 8. Among them, Rab11-FIP1A-D have carboxyl terminal Rab11 binding domains, while Rab11-FIP1E-H do not contain the Rab11 binding domain. While Rab11-FIP1B and F gene transcripts are ubiquitous, other Rab11-FIP1 transcripts demonstrate more limited patterns of expression in human tissue cDNAs. EGFP-Rab11-FIP1A-D proteins over-expressed in HeLa cells targeted to Rab11a-containing membranes, while EGFP-Rab11-FIP1E/F and H proteins did not localize with recycling system membranes. However, transferrin trafficking was not significantly altered in HeLa cells over-expressing expressing any of the EGFP-Rab11-FIP1 proteins. Rabbit polyclonal antibodies specific for Rab11-FIP1B and Rab11-FIP1C/RCP demonstrated that Rab11-FIP1B and Rab11-FIP1C/RCP are expressed endogenously. Strikingly, endogenous staining for Rab11-FIP1C/RCP only partially co-localized with EGFP-Rab11-FIP1A, EGFP-Rab11-FIP1B, and EGFP-Rab11a in the perinuclear region, indicating that Rab11-FIP1C/RCP resides in a differentiable subcellular compartment within the plasma membrane recycling system compared with Rab11-FIP1A and Rab11-FIP1B. These data suggest that Rab11-FIP1 proteins may play coordinated roles in regulating plasma membrane recycling with regional specificity within the Rab11a-containing recycling system.

  9. 基于SSH集成框架的报表综合分析平台设计%the statements Comprehensive Analysis platform's design based on ssH integration Framework

    Institute of Scientific and Technical Information of China (English)

    彭川

    2014-01-01

    In recent years, with the development of data modeling technology and intelligent management concept, comprehensive analysis report has been paid attention to and application of enterprise wide. This paper studies the general design of the system, discusses report comprehensive analysis platform system of open source framework technology based on the mode of MVc and struts, spring and Hibernate (ssH).By constructing the analysis to realize integration of ERP system internal and external data model for business, enterprise management status of scientiifc, accurate, analysis, monitoring and early warning and timely provide an effective, reliable, low cost management.%近年来,随着数据建模技术的发展和智能化管理概念的兴起,综合分析报表得到了企业广泛的重视和应用。本文从系统总体设计、研究的角度探讨了基于MVC模式及Struts 、Spring 和Hibernate (SSH)开源框架技术的报表综合分析平台系统的搭建,通过构建业务分析模型实现对ERP系统内外部数据的集成整合,为进行企业经营状况科学、准确、及时的分析、监控和预警提供了一种有效、可靠、低成本的管理手段。

  10. Identification of Legionella pneumophila rcp, a pagP-like gene that confers resistance to cationic antimicrobial peptides and promotes intracellular infection.

    Science.gov (United States)

    Robey, M; O'Connell, W; Cianciotto, N P

    2001-07-01

    In the course of characterizing a locus involved in heme utilization, we identified a Legionella pneumophila gene predicted to encode a protein with homology to the product of the Salmonella enterica serovar Typhimurium pagP gene. In Salmonella, pagP increases resistance to the bactericidal effects of cationic antimicrobial peptides (CAMPs). Mutants with insertions in the L. pneumophila pagP-like gene were generated and showed decreased resistance to different structural classes of CAMPs compared to the wild type; hence, this gene was designated rcp for resistance to cationic antimicrobial peptides. Furthermore, Legionella CAMP resistance was induced by growth in low-magnesium medium. To determine whether rcp had any role in intracellular survival, mutants were tested in the two most relevant host cells for Legionnaires' disease, i.e., amoebae and macrophages. These mutants exhibited a 1,000-fold-decreased recovery during a Hartmannella vermiformis coculture. Complementation of the infectivity defect could be achieved by introduction of a plasmid containing the intact rcp gene. Mutations in rcp consistently reduced both the numbers of bacteria recovered during intracellular infection and their cytopathic capacity for U937 macrophages. The rcp mutant was also more defective for lung colonization of A/J mice. Growth of rcp mutants in buffered yeast extract broth was identical to that of the wild type, indicating that the observed differences in numbers of bacteria recovered from host cells were not due to a generalized growth defect. However, in low-Mg(2+) medium, the rcp mutant was impaired in stationary-phase survival. This is the first demonstration of a pagP-like gene, involved in resistance to CAMPs, being required for intracellular infection and virulence.

  11. Applying IPCC Representative Concentration Pathway (RCP) land-use projections in a regional assessment of land-use change in the conterminous United States.

    Science.gov (United States)

    Sherba, J.; Sleeter, B. M.

    2015-12-01

    The Intergovernmental Panel on Climate Change (IPCC) Representative Concentration Pathways (RCPs) include global land-use change projections for four global emissions scenarios. These projections are potentially useful for driving regional-scale models needed for informing land-use and management interactions. Here, we applied global gridded RCP land-use projections within a regional-scale state-and-transition simulation model (STSM) projecting land-use change in the conterminous United States. First, we cross-walked RCP land-use transition classes to land-use classes more relevant for modeling at the regional scale. Coarse grid RCP land-use transition values were then downscaled to EPA Level III ecoregion boundaries using historical land-use transition data from the USGS Land Cover Trends (LCT) dataset. Downscaled transitions were aggregated to the ecoregion level. Ecoregions were chosen because they represent areas with consistent land-use patterns that have proven useful for studying land-use and management interactions. Ecoregion-level RCP projections were applied in a state-and-transition simulation model (STSM) projecting land-use change between 2005 and 2100 at the 1-km scale. Resulting RCP-based STSM projections were compared to STSM projections created using scenario projections from the Special Report on Emissions Scenarios (SRES) and the USGS LCT dataset. While most land-use trajectories appear plausible, some transitions such as forest harvest are unreasonable in the context of historical land-use patterns and the socio-economic drivers of change outlined for each scenario. This effort provides a method for using the RCP land-use projections in a wide range of regional scale models. However, further investigation is needed into the performance of RCP land-use projections at the regional scale.

  12. Structure-Function Analyses of the Interactions between Rab11 and Rab14 Small GTPases with Their Shared Effector Rab Coupling Protein (RCP)*

    Science.gov (United States)

    Lall, Patrick; Lindsay, Andrew J.; Hanscom, Sara; Kecman, Tea; Taglauer, Elizabeth S.; McVeigh, Una M.; Franklin, Edward; McCaffrey, Mary W.; Khan, Amir R.

    2015-01-01

    Rab GTPases recruit effector proteins, via their GTP-dependent switch regions, to distinct subcellular compartments. Rab11 and Rab25 are closely related small GTPases that bind to common effectors termed the Rab11 family of interacting proteins (FIPs). The FIPs are organized into two subclasses (class I and class II) based on sequence and domain organization, and both subclasses contain a highly conserved Rab-binding domain at their C termini. Yeast two-hybrid and biochemical studies have revealed that the more distantly related Rab14 also interacts with class I FIPs. Here, we perform detailed structural, thermodynamic, and cellular analyses of the interactions between Rab14 and one of the class I FIPs, the Rab-coupling protein (RCP), to clarify the molecular aspects of the interaction. We find that Rab14 indeed binds to RCP, albeit with reduced affinity relative to conventional Rab11-FIP and Rab25-FIP complexes. However, in vivo, Rab11 recruits RCP onto biological membranes. Furthermore, biophysical analyses reveal a noncanonical 1:2 stoichiometry between Rab14-RCP in dilute solutions, in contrast to Rab11/25 complexes. The structure of Rab14-RCP reveals that Rab14 interacts with the canonical Rab-binding domain and also provides insight into the unusual properties of the complex. Finally, we show that both the Rab coupling protein and Rab14 function in neuritogenesis. PMID:26032412

  13. Structure-Function Analyses of the Interactions between Rab11 and Rab14 Small GTPases with Their Shared Effector Rab Coupling Protein (RCP).

    Science.gov (United States)

    Lall, Patrick; Lindsay, Andrew J; Hanscom, Sara; Kecman, Tea; Taglauer, Elizabeth S; McVeigh, Una M; Franklin, Edward; McCaffrey, Mary W; Khan, Amir R

    2015-07-24

    Rab GTPases recruit effector proteins, via their GTP-dependent switch regions, to distinct subcellular compartments. Rab11 and Rab25 are closely related small GTPases that bind to common effectors termed the Rab11 family of interacting proteins (FIPs). The FIPs are organized into two subclasses (class I and class II) based on sequence and domain organization, and both subclasses contain a highly conserved Rab-binding domain at their C termini. Yeast two-hybrid and biochemical studies have revealed that the more distantly related Rab14 also interacts with class I FIPs. Here, we perform detailed structural, thermodynamic, and cellular analyses of the interactions between Rab14 and one of the class I FIPs, the Rab-coupling protein (RCP), to clarify the molecular aspects of the interaction. We find that Rab14 indeed binds to RCP, albeit with reduced affinity relative to conventional Rab11-FIP and Rab25-FIP complexes. However, in vivo, Rab11 recruits RCP onto biological membranes. Furthermore, biophysical analyses reveal a noncanonical 1:2 stoichiometry between Rab14-RCP in dilute solutions, in contrast to Rab11/25 complexes. The structure of Rab14-RCP reveals that Rab14 interacts with the canonical Rab-binding domain and also provides insight into the unusual properties of the complex. Finally, we show that both the Rab coupling protein and Rab14 function in neuritogenesis.

  14. An Investigation of Digital Payment Platform Designs

    DEFF Research Database (Denmark)

    Kazan, Erol; Damsgaard, Jan

    2014-01-01

    platforms that combines platform, technology and business design aspects. The framework is applied to conduct a comparative case study of digital payment platforms. Four types of market actors are considered: banks, mobile network operators, merchants, and startups, which are incumbents and disrupters....... By hosting third-party services, payment instruments are evolving from single-purpose to multi-functional ones. Our research extends existing payment literature from the MSP perspective to emphasize certain digital payment platform components, which impact strategies and complementary products....

  15. Research of Rapid Crack Propagation (RCP) Performance of Polyehylene Pressure Pipes%聚乙烯压力管材快速裂纹扩展(RCP)性能的研究

    Institute of Scientific and Technical Information of China (English)

    华晔; 武志军

    2014-01-01

    目前评价聚乙烯压力管材抗快速裂纹扩展(RCP)性能的测试方法有2种,全比例试验(FS)和小比例稳态试验(S4方法).相比FS方法,S4方法更简便和可控.研究了S4方法的影响因素,包括管材尺寸、样品安装时间、冲击速度等因素对RCP试验结果的影响.同时也研究了RCP性能和简支梁冲击强度及其他物理机械性能的关系.

  16. Projections of high resolution climate changes for South Korea using multiple-regional climate models based on four RCP scenarios. Part 1: surface air temperature

    Science.gov (United States)

    Suh, Myoung-Seok; Oh, Seok-Geun; Lee, Young-Suk; Ahn, Joong-Bae; Cha, Dong-Hyun; Lee, Dong-Kyou; Hong, Song-You; Min, Seung-Ki; Park, Seong-Chan; Kang, Hyun-Suk

    2016-05-01

    We projected surface air temperature changes over South Korea during the mid (2026-2050) and late (2076-2100) 21st century against the current climate (1981-2005) using the simulation results from five regional climate models (RCMs) driven by Hadley Centre Global Environmental Model, version 2, coupled with the Atmosphere- Ocean (HadGEM2-AO), and two ensemble methods (equal weighted averaging, weighted averaging based on Taylor's skill score) under four Representative Concentration Pathways (RCP) scenarios. In general, the five RCM ensembles captured the spatial and seasonal variations, and probability distribution of temperature over South Korea reasonably compared to observation. They particularly showed a good performance in simulating annual temperature range compared to HadGEM2-AO. In future simulation, the temperature over South Korea will increase significantly for all scenarios and seasons. Stronger warming trends are projected in the late 21st century than in the mid-21st century, in particular under RCP8.5. The five RCM ensembles projected that temperature changes for the mid/late 21st century relative to the current climate are +1.54°C/+1.92°C for RCP2.6, +1.68°C/+2.91°C for RCP4.5, +1.17°C/+3.11°C for RCP6.0, and +1.75°C/+4.73°C for RCP8.5. Compared to the temperature projection of HadGEM2-AO, the five RCM ensembles projected smaller increases in temperature for all RCP scenarios and seasons. The inter-RCM spread is proportional to the simulation period (i.e., larger in the late-21st than mid-21st century) and significantly greater (about four times) in winter than summer for all RCP scenarios. Therefore, the modeled predictions of temperature increases during the late 21st century, particularly for winter temperatures, should be used with caution.

  17. Future Climate Prediction of Urban Atmosphere in A Tropical Megacity: Utilization of RCP/SSP Scenarios with an Urban Growth Model

    Science.gov (United States)

    Darmanto, N. S.; Varquez, A. C. G.; Kanda, M.; Takakuwa, S.

    2016-12-01

    Economic development in Southeast Asia megacities leads to rapid transformation into more complicated urban configurations. These configurations, including building geometry, enhance aerodynamic drag thus reducing near-surface wind speeds. Roughness parameters representing building geometry, along with anthropogenic heat emissions, contribute to the formation of urban heat islands (UHI). All these have been reproduced successfully in the Weather Research and Forecasting (WRF) Model coupled with an improved single-layer urban canopy model incorporating a realistic distribution of urban parameters and anthropogenic heat emission in the Jakarta Greater Area. We apply this technology to climate change studies by introducing future urbanization defined by urban sprawl, vertical rise in buildings, and increase anthropogenic heat emission (AHE) due to population changes, into futuristic climate modelling. To simulate 2050s future climate, pseudo-global warming method was used which relied on current and ensembles of 5 CMIP5 GCMs for 2 representative concentration pathways (RCP), 2.6 and 8.5. To determine future urbanization level, 2050 population growth and energy consumption were estimated from shared socioeconomic pathways (SSP). This allows the estimation of future urban sprawl, building geometry, and AHE using the SLEUTH urban growth model and spatial growth assumptions. Two cases representing combinations of RCP and SSP were simulated in WRF: RCP2.6-SSP1 and RCP8.5-SSP3. Each case corresponds to best and worst-case scenarios of implementing adaptation and mitigation strategies, respectively. It was found that 2-m temperature of Jakarta will increase by 0.62°C (RCP2.6) and 1.44°C (RCP8.5) solely from background climate change; almost on the same magnitude as the background temperature increase of RCP2.6 (0.5°C) and RCP8.5 (1.2°C). Compared with previous studies, the result indicates that the effect of climate change on UHI in tropical cities may be lesser than

  18. Investigation of the Impact of a Heinrich-Event-like Abrupt Event Superimposed Onto the RCP 8.5 Scenario

    Science.gov (United States)

    Defrance, D.; Ramstein, G.; Dumas, C.; Charbit, S.

    2014-12-01

    The CMIP5/IPCC (AR5) projections of climate change showed the temperatures should increase by between 1.3 °C and 4.4 °C by 2100 and the sea level rise between 26 cm and 82 cm on average. Superimposed on these climatic and hydrologic trends associated with the RCP 8.5 most pessimistic scenario, it is important to investigate the possible effect of an abrupt event like an ice-sheet surge. This is first justified by the recent collapse of the Larsen B ice shelf which illustrates that a non-linear response of the cryosphere may occur in a warming world. Furthermore, in glacial periods, ice-sheets have been unstable and huge surges of icebergs did occur and deeply modified the climate. The aim of this presentation is to show the hypothetical climatic consequences of such a Heinrich-type event on future climate change. To achieve this goal, 3 scenarios of rapid ice-sheet deglaciation have been designed, corresponding to an additional sea level rise of around 3 m : - S1 corresponds to a contribution from Greenland only; - S2 from West-Antarctica only; - S3 from both ice-sheets. We use the global atmosphere-ocean general circulation model (OAGCM) IPSL-CM5A-LR. The freshwater perturbation is applied near the ice-sheet(s) during 20 years from 2050 to 2070 during an RCP8.5 perturbation. The RCP8.5 scenario is then continued until 2100 (without freshwater). For these types of scenarios, previous experiments for paleoclimatic cases help us diagnose the most vulnerable areas. The North Atlantic and the collapse of thermohaline circulation is one key issue, but far field teleconnections with the Asian monsoon will also be explored. We will investigate the timing and amplitude of the climate impacts due to the perturbations, which may be quite different in our 3 scenarios. These abrupt events consequences can be important for the populations and the consideration of rapid changes should improve the reliability of IPCC predictions.

  19. Platform development: implications for portfolio management

    DEFF Research Database (Denmark)

    Hsuan, Juliana; Hansen, Poul H. Kyvsgård

    2007-01-01

    " The challenge of implementing industrial platforms in practice can be described as a configuration problem caused by a considerable number of variables, which often have contradictory influences on the total performance of the firm. Consequently, the specific platform decisions become extremely...... a framework, based on the portfolio management thinking to evaluate the degree of modularity embedded in a given platform and to which extent it is aligned with other platforms."...... complex, possibly increasing the strategic risks for the firm. This paper reports preliminary findings on platform management process at LEGO, a Danish toy company. Specifically, we report the process of applying games combined with simulations and workshops in the platform development. We also propose...

  20. A new case of an inherited reciprocal translocation in cattle: rcp(13;26) (q24;q11).

    Science.gov (United States)

    Biltueva, Larisa; Kulemzina, Anastasia; Vorobieva, Nadezhda; Perelman, Polina; Kochneva, Marina; Zhidenova, Alexandra; Graphodatsky, Alexander

    2014-01-01

    This study reports on a unique balanced reciprocal chromosome translocation detected in a phenotypically normal cattle dam and her calf. CBG-, GTG-banding and FISH using bovine whole-chromosome and telomere probes were applied. The analyses showed that the breakpoints were located near to the centromere in chromosome 26 (q11) and exceptionally close to the telomere in chromosome 13 (q24). The whole euchromatin segment of chromosome 26 was translocated onto chromosome 13. The distal end of chromosome 13 was translocated to the subcentromeric region of chromosome 26. We describe this aberration as a balanced reciprocal translocation rcp(13;26) (q24;q11). It appears that this aberration was maternally derived and may have originated de novo in the dam. © 2014 S. Karger AG, Basel.

  1. Offshore wind energy climate projection using UPSCALE climate data under the RCP8.5 emission scenario

    CERN Document Server

    Gross, Markus

    2015-01-01

    Recently it was demonstrated how climate data can be utilized to estimate regional wind power densities. In particular it was shown that the quality of the global scale estimate compared well with regional high resolution studies and a link between surface temperature and moist density in the estimate was presented. In the present paper the methodology is tested further, to ensure that the results using one climate data set are reliable. This is achieved by extending the study to include four ensemble members. With the confidence that one instantiation is sufficient a climate change data set, which was also a result of the UPSCALE experiment, is analyzed. This, for the first time, provides a projection of future changes in wind power resources using this data set. This climate change data set is based on the Representative Concentration Pathways (RCP) 8.5 climate change scenario. This provides guidance for developers and policy makers to mitigate and adapt.

  2. Projection in Future Drought Hazard of South Korea Based on RCP Climate Change Scenario 8.5 Using SPEI

    Directory of Open Access Journals (Sweden)

    Byung Sik Kim

    2016-01-01

    Full Text Available The Standardized Precipitation Evapotranspiration Index (SPEI analysis was conducted using monthly precipitation data and temperature data on a 12.5 km × 12.5 km resolution based on a Representative Concentration Pathways (RCP 8.5 climate change scenario, and the characteristics of drought were identified by the threshold. In addition, the changes in drought severity and intensity were projected using the threshold based on the run-length concept and frequency analysis. As a result of the analysis, the probability density function of the total drought and maximum drought intensity moved the upper tail for the upcoming years, and the average drought intensity was also projected to become stronger in the future than in the present to the right side. Through this, it could be projected that the drought scale and frequency and the drought intensity will become severer over South Korea because of future climate change.

  3. Comparasion research of PFI and RCP financing mode%PFI和RCP融资模式的比较研究

    Institute of Scientific and Technical Information of China (English)

    杨涛; 徐霞; 于艳霞

    2011-01-01

    把当今比较流行的PFI融资模式和正处于理论研究阶段RCP模式在历史背景、特点、优缺点方面进行了详细的比较分析,以期给政府在非经营性或准经营性基础设施项目融资模式选择时提供一些参考意见。%According to analyzing and comparing the history background,merits and shortcomings etc.of PFI popular financing mode and RCP mode in the stage of theoretical research,the paper provides development direction and reference for government department choosi

  4. Projections of 2.0°C Warming over the Globe and China under RCP4.5

    Institute of Scientific and Technical Information of China (English)

    Zhang Ying

    2012-01-01

    The outputs of 17 models in the Coupled Model Intercomparison Project Phase 5 (CMIP5) are employed to investigate the temporal and spatial features of 2.0°C warming of the surface temperature over the globe and China under the Representative Concentration Pathways (RCP) 4.5 scenario. The simulations of the period 1860–1899 in the "historical" experiment are chosen as the baseline. The simulations for the 21st century in the RCP4.5 experiment are chosen as the future project. The multi-model ensemble mean (MME) shows that the global mean temperature would cross the 2.0°C warming threshold in 2047. Warming in most of the models would cross the threshold during 2030–2060. For local warming, high-latitude areas in the Northern Hemisphere show the fastest warming over the globe. Land areas warm substantially faster than the oceans. Most of the southern oceans would not exceed the 2.0°C warming threshold within the 21st century. Over China, surface warming is substantially faster than the global mean. The area-averaged warming would cross the 2.0°C threshold in 2034. Locally, Northwest China shows the fastest warming trend, followed by Central North China and Northeast China. Central China, East China, and South China are the last to cross the 2.0°C warming threshold. The diversity of the models is also estimated in this study. Generally, the spread among the models increases with time, and there is smaller spread among the models for the areas with the faster warming.

  5. FMN-coated fluorescent iron oxide nanoparticles for RCP-mediated targeting and labeling of metabolically active cancer and endothelial cells.

    Science.gov (United States)

    Jayapaul, Jabadurai; Hodenius, Michael; Arns, Susanne; Lederle, Wiltrud; Lammers, Twan; Comba, Peter; Kiessling, Fabian; Gaetjens, Jessica

    2011-09-01

    Riboflavin is an essential vitamin for cellular metabolism and is highly upregulated in metabolically active cells. Consequently, targeting the riboflavin carrier protein (RCP) may be a promising strategy for labeling cancer and activated endothelial cells. Therefore, Ultrasmall SuperParamagnetic Iron Oxide nanoparticles (USPIO) were adsorptively coated with the endogenous RCP ligand flavin mononucleotide (FMN), which renders them target-specific and fluorescent. The core diameter, surface morphology and surface coverage of the resulting FMN-coated USPIO (FLUSPIO) were evaluated using a variety of physico-chemical characterization techniques (TEM, DLS, MRI and fluorescence spectroscopy). The biocompatibility of FLUSPIO was confirmed using three different cell viability assays (Trypan blue staining, 7-AAD staining and TUNEL). In vitro evaluation of FLUSPIO using MRI and fluorescence microscopy demonstrated high labeling efficiency of cancer cells (PC-3, DU-145, LnCap) and activated endothelial cells (HUVEC). Competition experiments (using MRI and ICP-MS) with a 10- and 100-fold excess of free FMN confirmed RCP-specific uptake of the FLUSPIO by PC-3 cells and HUVEC. Hence, RCP-targeting via FMN may be an elegant way to render nanoparticles fluorescent and to increase the labeling efficacy of cancer and activated endothelial cells. This was shown for FLUSPIO, which due to their high T(2)-relaxivity, are favorably suited for MR cell tracking experiments and cancer detection in vivo. Copyright © 2011 Elsevier Ltd. All rights reserved.

  6. Changes in atmospheric blocking characteristics within Euro-Atlantic region and Northern Hemisphere as a whole in the 21st century from model simulations using RCP anthropogenic scenarios

    Science.gov (United States)

    Mokhov, Igor I.; Timazhev, Alexander V.; Lupo, Anthony R.

    2014-11-01

    An analysis of simulations using the IPSL-CM5 climate model of general circulation shows the ability of this model to reproduce the current climate of the main blocking characteristics obtained from reanalysis data, including number of blocking events and their duration, intensity and frequency. Possible changes of blocking characteristics in the Euro-Atlantic region (EA) and for the Northern Hemisphere (NH) as a whole are estimated from model simulations with the RCP2.6 and RCP8.5 scenarios for the 21st century. Results of the model simulations show a general increase in the blocking frequency for the EA in winter, summer and for the entire year during the 21st century for both analyzed RCP scenarios, while changes of the opposite sign are characteristic for NH as a whole. It is also noted that there is a tendency for an increase in the blocking intensity in the EA during the winter from model simulations with both analyzed RCP scenarios for the 21st century. A significant increase is obtained in the EA for the likelihood of extreme winter with the total blocking duration longer than seven weeks. Also, a similar tendency is characteristic for the EA summer.

  7. From Land Use to Land Cover: Restoring the Afforestation Signal in a Coupled Integrated Assessment - Earth System Model and the Implications for CMIP5 RCP Simulations

    Science.gov (United States)

    Di Vittorio, A. V.; Chini, L. P.; Bond-Lamberty, B. P.; Mao, J.; Shi, X.; Truesdale, J. E.; Craig, A.; Calvin, K. V.; Jones, A. D.; Collins, W.; Edmonds, J.; Hurtt, G. C.; Thornton, P. E.; Thomson, A. M.

    2014-12-01

    Climate projections depend on scenarios of fossil fuel emissions and land use change, and the IPCC AR5 parallel process assumes consistent climate scenarios across Integrated Assessment and Earth System Models (IAMs and ESMs). The CMIP5 project used a novel "land use harmonization" based on the Global Land use Model (GLM) to provide ESMs with consistent 1500-2100 land use trajectories generated by historical data and four IAM projections. A direct coupling of the Global Change Assessment Model (GCAM), GLM, and the Community ESM (CESM) has allowed us to characterize and partially address a major gap in the CMIP5 land coupling design: the lack of a corresponding land cover harmonization. The CMIP5 CESM global afforestation is only 22% of GCAM's 2005 to 2100 RCP4.5 afforestation. Likewise, only 17% of GCAM's 2040 RCP4.5 afforestation, and zero pasture loss, were transmitted to CESM within the directly coupled model. This is a problem because afforestation was relied upon to achieve RCP4.5 climate stabilization. GLM modifications within the directly coupled model did not increase CESM afforestation. Modifying the CESM land use translator in addition to GLM, however, enabled CESM to simulate 66% of GCAM's afforestation in 2040, and 94% of GCAM's pasture loss as grassland and shrubland losses. This additional afforestation increases vegetation carbon gain by 19 PgC and decreases atmospheric CO2 gain by 8 ppmv from 2005 to 2040, implying different RCP4.5 climate scenarios between CMIP5 GCAM and CESM. Although the IAMs and ESMs were not expected to have exactly the same climate forcing, due in part to different terrestrial carbon cycles and atmospheric radiation algorithms, the ESMs were expected to project climates representative of the RCP scenarios. Similar land cover inconsistencies exist in other CMIP5 model results, primarily because land cover information is not shared between IAM and ESM models. High RCP4.5 afforestation might also contribute to inconsistencies as

  8. From land use to land cover: restoring the afforestation signal in a coupled integrated assessment – earth system model and the implications for CMIP5 RCP simulations

    Directory of Open Access Journals (Sweden)

    A. V. Di Vittorio

    2014-05-01

    Full Text Available Climate projections depend on scenarios of fossil fuel emissions and land use change, and the IPCC AR5 parallel process assumes consistent climate scenarios across Integrated Assessment and Earth System Models (IAMs and ESMs. The CMIP5 project used a novel "land use harmonization" based on the Global Land use Model (GLM to provide ESMs with consistent 1500–2100 land use trajectories generated by historical data and four IAM projections. A direct coupling of the Global Change Assessment Model (GCAM, GLM, and the Community ESM (CESM has allowed us to characterize and partially address a major gap in the CMIP5 land coupling design: the lack of a corresponding land cover harmonization. The CMIP5 CESM global afforestation is only 22% of GCAM's 2005 to 2100 RCP4.5 afforestation. Likewise, only 17% of GCAM's 2040 RCP4.5 afforestation, and zero pasture loss, were transmitted to CESM within the directly coupled model. This is a problem because afforestation was relied upon to achieve RCP4.5 climate stabilization. GLM modifications within the directly coupled model did not increase CESM afforestation. Modifying the land use translator in addition to GLM, however, enabled CESM to simulate 66% of GCAM's afforestation in 2040, and 94% of GCAM's pasture loss as grassland and shrubland losses. This additional afforestation increases vegetation carbon gain by 19 PgC and decreases atmospheric CO2 gain by 8 ppmv from 2005 to 2040, implying different RCP4.5 climate scenarios between CMIP5 GCAM and CESM. Although the IAMs and ESMs were not expected to have exactly the same climate forcing, due in part to different terrestrial carbon cycles and atmospheric radiation algorithms, the ESMs were expected to project climates representative of the RCP scenarios. Similar land cover inconsistencies exist in other CMIP5 model results, primarily because land cover information is not shared between models. High RCP4.5 afforestation might also contribute to inconsistencies as

  9. Business and IT Capabilities for Cloud Platform Success

    DEFF Research Database (Denmark)

    Hahn, Christopher; Huntgeburth, Jan; Winkler, Till J.

    2016-01-01

    The growing proliferation of cloud platform ecosystems demands a deeper understanding of the capabilities that help existing and emerging platform providers to be successful by creating and appropriating value. This multiple case study of four cloud platform providers (three large, one SME......) instantiates Rai and Tang’s (2014) framework of dyadic IT and network IT capabilities for a cloud platform context and extends it by exploring previously undertheorized cloud platform business capabilities. We further build on this extended framework by employing a configurational perspective to elucidate...... the complementary role of the three proposed business capabilities (incentives and rules, ecosystem marketing and sales, partner development and support) for relevant value creation and appropriation mechanisms. In addition to providing a capability framework catered to the cloud platform context, our findings...

  10. Interfacing Clojure with Pogamut 3 platform

    Science.gov (United States)

    Gołuński, Marcel; WÄ siewicz, Piotr

    In this paper we present an interface between Pogamut 3 platform and Clojure programming language. Clojure is a state of the art functional language with roots in Lisp. Pogamut 3 is a framework that simplifies creation of embodied agents. Our goal was to introduce Clojure code in our agents logic. Simple emergent behavior of a group of agents was implemented using Clojure code. Performance of execution of Clojure code called from Pogamut platform was measured.

  11. 基于GNU Radio架构的信号处理实验平台开发%Development of signal processing experimental platform based on GNU Radio framework

    Institute of Scientific and Technical Information of China (English)

    张建良; 吴越; 齐冬莲

    2016-01-01

    开发了基于GNU Radio的信号分析与处理实验平台.借助GNU Radio完全开源的信号分析处理平台,既能够提供开放式可修改的模块库,以便快速建立关于信号处理的流程并进行内容设计、仿真,又能够用来连接真实的信号接收和处理系统,方便进行综合性和探究性实验设计.该实验平台的建立,方便学生以更加灵活的学习形式获取专业的资源,进行更加灵活多样的学习和互动,并有助于提高实验教学效果.%The signal analysis and processing experimental platform based on GNU Radio is developed.By using the fully open source GNU Radio based signal analysis and processing platform,an open and modifiable library of modules can be provided so as to establish the quick signal processing flow and carry out the content design and simulation.At the same time,the platform can be used to connect the real signal receiving and processing system,which is easy to carry out the comprehensive and exploratory experimental design.The establishment of the experimental platform can help the students to obtain the specialized resources in a more flexible learning method and carry out more flexible and interactive learning,and the platform can also contribute to the improvement of the experimental teaching effect.

  12. Assessing global fossil fuel availability in a scenario framework

    Energy Technology Data Exchange (ETDEWEB)

    Bauer, Nico; Hilaire, Jerome; Brecha, Robert J.; Edmonds, James A.; Jiang, Kejun; Kriegler, Elmar; Rogner, Hans-Holger; Sferra, Fabio

    2016-06-01

    This study assesses global, long-term economic availability of coal, oil and gas within the Shared Socio-economic Pathway (SSP) scenario framework considering alternative assumptions as to highly uncertain future developments of technology, policy and the economy. Diverse sets of trajectories are formulated varying the challenges to mitigation and adaptation of climate change. The potential CO2 emissions from fossil fuels make it a crucial element subject to deep uncertainties. The analysis is based on a well-established data set of cost-quantity combinations that assumes favorable techno-economic developments, but ignores additional constraints on the extraction sector. This study significantly extends that analysis to include alternative assumptions for the fossil fuel sector consistent with the SSP scenario families and applies these filters to the original data set, thus resulting in alternative cumulative fossil fuel availability curves. In a Middle-of-the-Road scenario, low cost fossil fuels embody carbon consistent with a RCP6.0 emission profile, if all the CO2 were emitted freely during the 21st century. In scenarios with high challenges to mitigation, the assumed embodied carbon in low-cost fossil fuels can trigger a RCP8.5 scenario; low mitigation challenges scenarios are still consistent with a RCP4.5 scenario.

  13. Product Platform Performance

    DEFF Research Database (Denmark)

    Munk, Lone

    engaging in platform-based product development. Similarly platform assessment criteria lack empirical verification regarding relevance and sufficiency. The thesis focuses on • the process of identifying and estimating internal effects, • verification of performance of product platforms, (i...... to support this understanding. Finally a categorisation of different approaches to platform-based product development is introduced, based on the companies from the industrial study.......The aim of this research is to improve understanding of platform-based product development by studying platform performance in relation to internal effects in companies. Platform-based product development makes it possible to deliver product variety and at the same time reduce the needed resources...

  14. Business and IT Capabilities for Cloud Platform Success

    DEFF Research Database (Denmark)

    Hahn, Christopher; Huntgeburth, Jan; Winkler, Till J.

    2016-01-01

    the complementary role of the three proposed business capabilities (incentives and rules, ecosystem marketing and sales, partner development and support) for relevant value creation and appropriation mechanisms. In addition to providing a capability framework catered to the cloud platform context, our findings......) instantiates Rai and Tang’s (2014) framework of dyadic IT and network IT capabilities for a cloud platform context and extends it by exploring previously undertheorized cloud platform business capabilities. We further build on this extended framework by employing a configurational perspective to elucidate...

  15. Projecting potential distribution of Eucryptorrhynchus scrobiculatus Motschulsky and E. brandti (Harold) under historical climate and RCP 8.5 scenario.

    Science.gov (United States)

    Ji, Yingchao; Luo, Wen; Zhang, Ganyu; Wen, Junbao

    2017-08-22

    Ailanthus altissima (Mill.) Swingle and its variant A. altissima var. Qiantouchun are notorious invasive weeds. Two weevils, Eucryptorrhynchus scrobiculatus (ESC) and E. brandti (EBR) are considered as candidates for biological control of A. altissima. The aim of this study was to model the potential distributions of ESC and EBR using CLIMEX 4.0. The projected potential distributions of ESC and EBR included almost all current distribution areas of A. altissima, except Southeast Asia. Under historical climate, potential distribution area of EBR is larger than that of ESC, 46.67 × 10(6) km(2) and 35.65 × 10(6) km(2), respectively. For both ESC and EBR, climate change expanded the northern boundary of potential distributions northward approximately 600 km by the middle of 21st century, and 1000 km by the end of 21st century under RCP 8.5. However, the suitable range decreased to the south in the Southern Hemisphere because of heat stress. The modelled potential distributions of ESC and EBR in the United States demonstrated that the climate was suitable for both weevils. Therefore, considering only climate suitability, both ESC and EBR can be considered as potential biological control agents against A. altissima with some confidence that climatic conditions are likely suitable.

  16. A new case of reciprocal translocation in a young bull: rcp(11;21)(q28;q12).

    Science.gov (United States)

    Molteni, L; Perucatti, A; Iannuzzi, A; Di Meo, G P; De Lorenzi, L; De Giovanni, A; Incarnato, D; Succi, G; Cribiu, E; Eggen, A; Iannuzzi, L

    2007-01-01

    Routine cytogenetic investigations of the Chianina cattle (BTA) breed revealed the presence of longer and smaller chromosomes than the largest (BTA1) and smallest (BTA29) chromosomes in the cells of a young, normal-looking bull used for reproduction. Application of both RBA-banding and Ag-NOR techniques, as well as the use of the FISH technique and specific molecular markers of both BTA11 (IL1B, ASS and LGB) and BTA21 (SERPINA and D21S45) established that these two abnormal chromosomes were the product of a reciprocal translocation between BTA11 and BTA21. Both der(11) and der(21) were C-band positive and the chromosome regions affected were rcp(11;21)(q28;q12). The young bull had a normal body conformation, including external genitalia, normal levels of testosterone (as in the control) and non-detectable levels of both 17 beta-estradiol and progesterone (as in the control). The animal never showed libido in the presence of both males and females in oestrus. After slaughter at 18 months, histological evaluation revealed normal organized testes, seminiferous tubules and epididymis but with poor proliferative germ cells consisting mainly of spermatogonia, middle pachytene spermatocytes and early spermatids with late spermatids and spermatozoa being very rare. Copyright 2007 S. Karger AG, Basel.

  17. Future PMP Estimation in Korea under AR5 RCP 8.5 climate change scenarios and its Changes Cause Analysis

    Science.gov (United States)

    Kim, S.; Lee, J.; Okjeong, L.; Bogyeong, C.; Park, M. W.

    2015-12-01

    In this presentation, Korea's probable maximum precipitations (PMPs) which reflects all of the storm data until recently are calculated, and are compared to the existing PMPs which were calculated at 2000. In Korea, abnormal weather phenomena such as typhoon Rusa and Maemi, and the extreme rainfall event occurred on the east coast of the northern region, that can have a significant impact on the PMP estimation, have frequently happened since 2000. After selecting 240 major storm events from 1973 to 2012, new PMPs are proposed with respect to storm areas (25, 100, 225, 400, 900, 2025, 4900, 10000 and 19600 km2) and storm durations (1, 2, 4, 6, 8, 12, 18, 24, 48 and 72 hours) using the Korea hydro-meteorological method. After estimating future PMPs using future rainfall and dew point temperature information under the Korea Meteorological Administration AR5 RCP 8.5, changes in the PMPs under climate change will be investigated by comparison with present and future PMPs. By separating the changes in PMPs under climate change into the changes caused by rainfall and dew point temperature, the relative impact of future rainfall and dew point temperature information under climate change on future PMPs is quantified. This research was supported by a grant 'Development of the Evaluation Technology for Complex Causes of Inundation Vulnerability and the Response Plans in Coastal Urban Areas for Adaptation to Climate Change' [MPSS-NH-2015-77] from the Natural Hazard Mitigation Research Group, Ministry of Public Safety and Security of Korea.

  18. Coupled wave-atmosphere-ocean modeling under RCP8.5 emissions during the 21st century

    Science.gov (United States)

    de Vries, Hylke; Semedo, Alvaro; Sterl, Andreas

    2016-04-01

    Most climate models have no explicit treatment of surface ocean waves. As a result, wave climatologies are usually obtained off-line, using atmospheric forcing as input. In recent years attempts have been made to incorporate surface ocean wave models into GCMs, giving the possibility of interactions between components. In the presence of waves the atmospheric winds are modified due to different drag-coefficient and breaking waves will have also influence vertical ocean mixing. As such the waves may play a role in solving long-standing ocean and atmospheric biases. Recently we have coupled the global wave model WAM into EC-Earth GCM (v3.0.1). EC-Earth is based on the IFS atmospheric model and the NEMO/LIM ocean/sea ice model. First results are presented from a 140-year (1961-2100) continuous transient, coupled simulation under RCP8.5 emission scenario. As the modelled climate warms during the transient period, (arctic) sea-ice gradually diminishes, allowing surface waves to penetrate to higher and higher latitudes. Eventually Arctic sea-ice completely disappears in the simulation in late summer. We will discuss swell and wind-wave climatologies, Stokes drift patterns as well as other relevant wave parameters.

  19. Product Platform Modeling

    DEFF Research Database (Denmark)

    Pedersen, Rasmus

    on the notion that reuse and encapsulation of platform elements are fundamental characteristics of a product platform. Reuse covers the desire to reuse and share certain assets across a family of products and/or across generations of products. Product design solutions and principles are often regarded...... as important assets in a product platform, yet activities, working patterns, processes and knowledge can also be reused in a platform approach. Encapsulation is seen as a process in which the different elements of a platform are grouped into well defined and self-contained units which are decoupled from each......This PhD thesis has the title Product Platform Modelling. The thesis is about product platforms and visual product platform modelling. Product platforms have gained an increasing attention in industry and academia in the past decade. The reasons are many, yet the increasing globalisation...

  20. Three dimensional calculations of the primary coolant flow in a 900 MW PWR vessel. Numerical simulation of the accurate RCP start-up flow rate

    Energy Technology Data Exchange (ETDEWEB)

    Martin, A.; Alvarez, D.; Cases, F.; Stelletta, S. [Electricite de France (EDF), 78 - Chatou (France). Lab. National d`Hydraulique

    1997-06-01

    This report explains the last results about the mixing in the 900 MW PWR vessels. The accurate fluid flow transient, induced by the RCP starting-up, is represented. In a first time, we present the Thermalhydraulic Finite Element Code N3S used for the 3D numerical computations. After that, results obtained for one reactor operation case are given. This case is dealing with the transient mixing of a clear plug in the vessel when one primary pump starts-up. A comparison made between two injection modes; a steady state fluid flow conditions or the accurate RCP transient fluid flow conditions. The results giving the local minimum of concentration and the time response of the mean concentration at the core inlet are compared. The results show the real importance of the unsteadiness characteristics of the fluid flow transport of the clear water plug. (author) 12 refs.

  1. Prediction of abundance of arthropods according to climate change scenario RCP 4.5 and 8.5 in South Korea

    Directory of Open Access Journals (Sweden)

    Cheol Min Lee

    2016-06-01

    Full Text Available Abundance and diversity of arthropods were projected according to climate warming in South Korea. The taxa highly linked with temperature were selected for the projection. The values of abundance and richness were estimated using the mean values of abundance and richness in each temperature range. Temperature changes were based on the RCP (Representative Concentration Pathway 4.5 and RCP 8.5, and the abundance and richness during two periods (2011 -2015, 2056 -2065 were projected. From these projected results, change of other common taxa (> 1% occurrence were qualitatively predicted (i.e., decrease or increase. The projections showed that 45 of a total of 73 taxa will increase, 6 will change a little and 24 will decrease: the number of taxa that were expected to increase was two times more than the number of taxa that were expected to decrease. However, the overall abundance and diversity of arthropods were expected to decline as the temperature rises.

  2. PREPARATION OF POLYMER—SUPPORTED RCpCpTiCl2 AND APPLICATION IN CATALYTIC ISOMERIZATION OF 1,5—HEXADIENE

    Institute of Scientific and Technical Information of China (English)

    QIANYanlong; HONGKunlun; 等

    1993-01-01

    Polymer-supported RCpCpTiCl2(Cp=η5-C5H4;RCp=η5-RC5H4)have been prepared and reduced by i-C3H7MgBr in situ,then used in catalytic isomerization of 1,5-hexadiene.The isomerization of 1,5-hexadiene leads to a mixture of cyclic and linear products.The ratio of cyclic to linear product depends on the nature of the supporter and the substituent on the cyclopentadienyl ring.The former contributes the most,for example,silica supported Cp2 TiCl2 gave cyclic-linear ratio of 99/1,while for polymer-supported Cp2TiCl2 species,linear compounds are the major products and the ratio of cyclic to linear product changes with different R groups on the cyclopentadienyl ring.

  3. Projections of high resolution climate changes for South Korea using multiple-regional climate models based on four RCP scenarios. Part 2: precipitation

    Science.gov (United States)

    Oh, Seok-Geun; Suh, Myoung-Seok; Lee, Young-Suk; Ahn, Joong-Bae; Cha, Dong-Hyun; Lee, Dong-Kyou; Hong, Song-You; Min, Seung-Ki; Park, Seong-Chan; Kang, Hyun-Suk

    2016-05-01

    Precipitation changes over South Korea were projected using five regional climate models (RCMs) with a horizontal resolution of 12.5 km for the mid and late 21st century (2026-2050, 2076- 2100) under four Representative Concentration Pathways (RCP) scenarios against present precipitation (1981-2005). The simulation data of the Hadley Centre Global Environmental Model version 2 coupled with the Atmosphere-Ocean (HadGEM2-AO) was used as boundary data of RCMs. In general, the RCMs well simulated the spatial and seasonal variations of present precipitation compared with observation and HadGEM2-AO. Equal Weighted Averaging without Bias Correction (EWA_NBC) significantly reduced the model biases to some extent, but systematic biases in results still remained. However, the Weighted Averaging based on Taylor's skill score (WEA_Tay) showed a good statistical correction in terms of the spatial and seasonal variations, the magnitude of precipitation amount, and the probability density. In the mid-21st century, the spatial and interannual variabilities of precipitation over South Korea are projected to increase regardless of the RCP scenarios and seasons. However, the changes in area-averaged seasonal precipitation are not significant due to mixed changing patterns depending on locations. Whereas, in the late 21st century, the precipitation is projected to increase proportionally to the changes of net radiative forcing. Under RCP8.5, WEA_Tay projects the precipitation to be increased by about +19.1, +20.5, +33.3% for annual, summer and winter precipitation at 1-5% significance levels, respectively. In addition, the probability of strong precipitation (≥ 15 mm d-1) is also projected to increase significantly, particularly in WEA_Tay under RCP8.5.

  4. RCP-driven α5β1 recycling suppresses Rac and promotes RhoA activity via the RacGAP1–IQGAP1 complex

    Science.gov (United States)

    Jacquemet, Guillaume; Green, David M.; Bridgewater, Rebecca E.; von Kriegsheim, Alexander; Humphries, Martin J.; Norman, Jim C.

    2013-01-01

    Inhibition of αvβ3 or expression of mutant p53 promotes invasion into fibronectin (FN)-containing extracellular matrix (ECM) by enhancing Rab-coupling protein (RCP)–dependent recycling of α5β1 integrin. RCP and α5β1 cooperatively recruit receptor tyrosine kinases, including EGFR1, to regulate their trafficking and downstream signaling via protein kinase B (PKB)/Akt, which, in turn, promotes invasive migration. In this paper, we identify a novel PKB/Akt substrate, RacGAP1, which is phosphorylated as a consequence of RCP-dependent α5β1 trafficking. Phosphorylation of RacGAP1 promotes its recruitment to IQGAP1 at the tips of invasive pseudopods, and RacGAP1 then locally suppresses the activity of the cytoskeletal regulator Rac and promotes the activity of RhoA in this subcellular region. This Rac to RhoA switch promotes the extension of pseudopodial processes and invasive migration into FN-containing matrices, in a RhoA-dependent manner. Thus, the localized endocytic trafficking of α5β1 within the tips of invasive pseudopods elicits signals that promote the reorganization of the actin cytoskeleton, protrusion, and invasion into FN-rich ECM. PMID:24019536

  5. RCP-driven α5β1 recycling suppresses Rac and promotes RhoA activity via the RacGAP1-IQGAP1 complex.

    Science.gov (United States)

    Jacquemet, Guillaume; Green, David M; Bridgewater, Rebecca E; von Kriegsheim, Alexander; Humphries, Martin J; Norman, Jim C; Caswell, Patrick T

    2013-09-16

    Inhibition of αvβ3 or expression of mutant p53 promotes invasion into fibronectin (FN)-containing extracellular matrix (ECM) by enhancing Rab-coupling protein (RCP)-dependent recycling of α5β1 integrin. RCP and α5β1 cooperatively recruit receptor tyrosine kinases, including EGFR1, to regulate their trafficking and downstream signaling via protein kinase B (PKB)/Akt, which, in turn, promotes invasive migration. In this paper, we identify a novel PKB/Akt substrate, RacGAP1, which is phosphorylated as a consequence of RCP-dependent α5β1 trafficking. Phosphorylation of RacGAP1 promotes its recruitment to IQGAP1 at the tips of invasive pseudopods, and RacGAP1 then locally suppresses the activity of the cytoskeletal regulator Rac and promotes the activity of RhoA in this subcellular region. This Rac to RhoA switch promotes the extension of pseudopodial processes and invasive migration into FN-containing matrices, in a RhoA-dependent manner. Thus, the localized endocytic trafficking of α5β1 within the tips of invasive pseudopods elicits signals that promote the reorganization of the actin cytoskeleton, protrusion, and invasion into FN-rich ECM.

  6. Installation and Commissioning of RCP Cartridge for Nuclear Power Stations%核电厂主泵密封系统的安装与调试

    Institute of Scientific and Technical Information of China (English)

    霍亚邦; 王玉旭

    2011-01-01

    The installation process and method for the cooling pump sealing system of CPR1000 nuclear power plant reactor is studied, and various cases occurred during the installation and commisioning of RCP sealing systems are analyzed. The scheme for flushing of the nuclear loop in the various cases is developed to provide a reference for the installation and commissioning of RCP sealing system in the coming CPR1000 project.%研究CPR1000堆型核电厂反应堆冷却剂泵(RCP)密封安装工艺流程及方法,对RCP密封系统安装和调试过程中的各种情况进行分析,制定各种情况下核回路冲洗采取的特殊处理方案,为后续CPR1000项目RCP密封系统安装调试提供参考.

  7. Research on Construction of Legal Supervision Framework of P2 P Lending Platform%P2 P网贷平台的法律监管框架构建研究

    Institute of Scientific and Technical Information of China (English)

    周亦鸣

    2016-01-01

    In recent years,P2P lending platforms have made great progress in China.Due to lack of special legislation and regulations,various risks exist in its operation.This article analyzes all kinds of risks and supervision dilemma of P2P lending platforms which exist in our country,compares regulation experience of USA and UK and proposes the basic thought of constructing and improving P2P supervision in China.We need to strengthen the construction of laws and regulations,combine government regulation and industrial self-discipline,and accelerate the construction of credit system.This article also proposes some suggestions on the regulatory principles,the regulatory authorities,the regulatory content and the regulatory means of P2P lending platform in our country.%近年来P2P网贷平台在我国发展迅速。由于缺乏对其专门立法和监管,导致其经营存在多种风险。文章分析了我国P2P行业的各种风险和监管困境,比较了英美两国的监管经验,提出了构建和完善我国P2P监管的基本思路应当是加强法律法规建设、政府监管和行业自律相结合、推进信用体系建设。文章还对我国 P2P 监管应采用的监管原则、监管机关、监管内容和监管手段提出了构想。

  8. Planning of Creative Commercial Components Virtual Warehouse Platform

    Directory of Open Access Journals (Sweden)

    Wang Yantao

    2013-07-01

    Full Text Available In this study, through the analysis of actual goods warehouse application, creative commercial components virtual warehouse platform over the networks is proposed to support the complex mechanical product commercial work mode. This platform may play an important role during the collaborative commodity design process, especially the geometrical model to the commercial model. First, the framework of commercial design process was described detailed with the supporting of virtual components warehouse platform. Then, those platform features such as networks-based, agent-oriented and enterprises alliance-served were discussed. The platform application modes, on-line stocking and inquiring were also classified. Finally, the planning framework of the commercial components virtual warehouse platform was studied detailed.

  9. Using the MVC architecture on . NET platform

    OpenAIRE

    Ježek, David

    2011-01-01

    This thesis deals with usage of MVC (Model View Controller) technology in web development on ASP.NET platform from Microsoft. Mainly it deals with latest version of framework ASP.NET MVC 3. First part describes MVC architecture and the second describes usage of MVC in certain parts of web application an comparing with PHP.

  10. ITS Platform North Denmark

    DEFF Research Database (Denmark)

    Lahrmann, Harry; Agerholm, Niels; Juhl, Jens

    2012-01-01

    This paper presents the project entitled “ITS Platform North Denmark” which is used as a test platform for Intelligent Transportation System (ITS) solutions. The platform consists of a newly developed GNSS/GPRS On Board Unit (OBU) to be installed in 500 cars, a backend server and a specially...... designed digital road map for ITS applications. The platform is freely accessible, which means that third party applications could be run on the platform. It is estimated that using this platform enables the ITS applications to be developed for 20% of the normal cost, hence third party are invited to test...... their applications in this platform. This paper presents the platform’s potentials and explains a series of test applications which are under development on it. Moreover, a number of new projects planned for the platform are demonstrated....

  11. Mobile platform security

    CERN Document Server

    Asokan, N; Dmitrienko, Alexandra

    2013-01-01

    Recently, mobile security has garnered considerable interest in both the research community and industry due to the popularity of smartphones. The current smartphone platforms are open systems that allow application development, also for malicious parties. To protect the mobile device, its user, and other mobile ecosystem stakeholders such as network operators, application execution is controlled by a platform security architecture. This book explores how such mobile platform security architectures work. We present a generic model for mobile platform security architectures: the model illustrat

  12. 五平台框架下的教师教育实验教学示范中心建设与研究%Construction and research on teacher education experimental center under five-platform framework

    Institute of Scientific and Technical Information of China (English)

    刘长宏; 苑晓杰

    2014-01-01

    The teacher education experimental center is an important base for training in specialized skills and innovative capacity of the normal school students. This article describes the construction principles ,platform system ,safeguards and operating results involved in the construction of teacher education experimental center which are mainly composed of the five platforms ,namely vocational skills ,professional development ,academic inquiry ,innovation and practice ,and research and service .%教师教育实验教学中心是师范大学师范生专业化技能与创新能力培养的重要基地。介绍了由职业技能、专业发展、学科探究、创新与实践、科研与服务五平台建构的教师教育实验教学中心建设原则、平台体系、保障措施及运行效果。

  13. A Cross-Platform Tactile Capabilities Interface for Humanoid Robots

    Directory of Open Access Journals (Sweden)

    Jie eMa

    2016-04-01

    Full Text Available This article presents the core elements of a cross-platform tactile capabilities interface (TCI for humanoid arms. The aim of the interface is to reduce the cost of developing humanoid robot capabilities by supporting reuse through cross-platform deployment. The article presents a comparative analysis of existing robot middleware frameworks, as well as the technical details of the TCI framework that builds on the the existing YARP platform. The TCI framework currently includes robot arm actuators with robot skin sensors. It presents such hardware in a platform independent manner, making it possible to write robot control software that can be executed on different robots through the TCI frameworks. The TCI framework supports multiple humanoid platforms and this article also presents a case study of a cross-platform implementation of a set of tactile protective withdrawal reflexes that have been realised on both the Nao and iCub humanoid robot platforms using the same high-level source code.

  14. Continuous Platform Development

    DEFF Research Database (Denmark)

    Nielsen, Ole Fiil

    low risks and investments but also with relatively fuzzy results. When looking for new platform projects, it is important to make sure that the company and market is ready for the introduction of platforms, and to make sure that people from marketing and sales, product development, and downstream......, but continuous product family evolution challenges this strategy. The concept of continuous platform development is based on the fact that platform development should not be a one-time experience but rather an ongoing process of developing new platforms and updating existing ones, so that product family...

  15. Design and Implement of a College Education CMS Service Platform based on Yaf Framework%基于Yaf的高校教育CMS服务平台的设计与实现

    Institute of Scientific and Technical Information of China (English)

    刘淇峰; 陈雪蛟

    2015-01-01

    As internet technology grows explosively, as the basic platform to display its information and share educa-tional resources,web site of departments in college play more and more important role in our daily life. However, the management technology is uneven,web sites’ structure and layout are not all the same and resources share diffi-cultly. All these problems make great hazard for further construction and management. As college website has its special users and managers, people should research and de-velop a general education content management system (CMS) service platform, which provides a reference for digi-tal campus environment to establish education resource sharing, make standardized management and improve the flexibility for controlling service.%随着互联网技术的发展,高校各院系、部门网站作为高校信息公开展示和教育资源共享的基础平台,地位日显重要。但管理人员技术水平参差不齐,网站结构布局各不相同,资源共享困难等问题,为网站日后的建设和管理埋下重大隐患。因此,需要针对高校网站使用人群和管理人群的特点,研究一个通用的教育内容管理系统(CMS)服务平台,为建立教育资源共享、统一规范管理、服务灵活配置的校园数字化生态环境提供参考。

  16. Cross-Platform Technologies

    Directory of Open Access Journals (Sweden)

    Maria Cristina ENACHE

    2017-04-01

    Full Text Available Cross-platform - a concept becoming increasingly used in recent years especially in the development of mobile apps, but this consistently over time and in the development of conventional desktop applications. The notion of cross-platform software (multi-platform or platform-independent refers to a software application that can run on more than one operating system or computing architecture. Thus, a cross-platform application can operate independent of software or hardware platform on which it is execute. As a generic definition presents a wide range of meanings for purposes of this paper we individualize this definition as follows: we will reduce the horizon of meaning and we use functionally following definition: a cross-platform application is a software application that can run on more than one operating system (desktop or mobile identical or in a similar way.

  17. Offshore Wind Energy Climate Projection Using UPSCALE Climate Data under the RCP8.5 Emission Scenario.

    Science.gov (United States)

    Gross, Markus; Magar, Vanesa

    2016-01-01

    In previous work, the authors demonstrated how data from climate simulations can be utilized to estimate regional wind power densities. In particular, it was shown that the quality of wind power densities, estimated from the UPSCALE global dataset in offshore regions of Mexico, compared well with regional high resolution studies. Additionally, a link between surface temperature and moist air density in the estimates was presented. UPSCALE is an acronym for UK on PRACE (the Partnership for Advanced Computing in Europe)-weather-resolving Simulations of Climate for globAL Environmental risk. The UPSCALE experiment was performed in 2012 by NCAS (National Centre for Atmospheric Science)-Climate, at the University of Reading and the UK Met Office Hadley Centre. The study included a 25.6-year, five-member ensemble simulation of the HadGEM3 global atmosphere, at 25km resolution for present climate conditions. The initial conditions for the ensemble runs were taken from consecutive days of a test configuration. In the present paper, the emphasis is placed on the single climate run for a potential future climate scenario in the UPSCALE experiment dataset, using the Representation Concentrations Pathways (RCP) 8.5 climate change scenario. Firstly, some tests were performed to ensure that the results using only one instantiation of the current climate dataset are as robust as possible within the constraints of the available data. In order to achieve this, an artificial time series over a longer sampling period was created. Then, it was shown that these longer time series provided almost the same results than the short ones, thus leading to the argument that the short time series is sufficient to capture the climate. Finally, with the confidence that one instantiation is sufficient, the future climate dataset was analysed to provide, for the first time, a projection of future changes in wind power resources using the UPSCALE dataset. It is hoped that this, in turn, will provide

  18. Platform switching and bone platform switching.

    Science.gov (United States)

    Carinci, Francesco; Brunelli, Giorgio; Danza, Matteo

    2009-01-01

    Bone platform switching involves an inward bone ring in the coronal part of the implant that is in continuity with the alveolar bone crest. Bone platform switching is obtained by using a dental fixture with a reverse conical neck. A retrospective study was performed to evaluate the effectiveness of conventional vs reverse conical neck implants. In the period between May 2004 and November 2007, 86 patients (55 females and 31 males; median age, 53 years) were operated and 234 implants were inserted: 40 and 194 were conventional vs reverse conical neck implants, respectively. Kaplan-Meier algorithm and Cox regression were used to detect those variables associated with the clinical outcome. No differences in survival and success rates were detected between conventional vs reverse conical neck implants alone or in combination with any of the studied variables. Although bone platform switching leads to several advantages, no statistical difference in alveolar crest resorption is detected in comparison with reverse conical neck implants. We suppose that the proximity of the implant abutment junction to the alveolar crestal bone gives no protection against the microflora contained in the micrograph. Additional studies on larger series and a combination of platform switching and bone platform switching could lead to improved clinical outcomes.

  19. 湖北省远程医疗服务平台架构设计与实践%The Design and Practice on Hubei Telemedicine Service Platform Framework

    Institute of Scientific and Technical Information of China (English)

    肖树发; 肖兴政; 韩素芳

    2015-01-01

    As the existed telemedicine system for construction is built by different stages, it is scattered and isolated between each other. It can't meet the needs of telemedicine between hospitals in Hubei province, and can't fully make the maximum benefit of system construction. This article takes Hubei provincial telemedicine service platform based on cloud computing as an example, and introduces the large-scale telemedicine system network scheme based on HD video equipment by using different brands and networks.%目前现有远程医疗系统因分期建设,分散孤立,系统之间互不相联,无法满足湖北省各级医院间开展远程医疗业务的需要,不能充分发挥系统建设的最大效益。本文以湖北省云模式远程医疗服务平台建设为例,介绍了基于高清视音频的跨品牌、跨网络、大规模远程医疗组网方案。

  20. Impacts of changes in climate and land use/land cover under IPCC RCP scenarios on streamflow in the Hoeya River Basin, Korea.

    Science.gov (United States)

    Kim, Jinsoo; Choi, Jisun; Choi, Chuluong; Park, Soyoung

    2013-05-01

    This study examined the separate and combined impacts of future changes in climate and land use/land cover (LULC) on streamflow in the Hoeya River Basin, South Korea, using the representative concentration pathway (RCP) 4.5 and 8.5 scenarios of the Fifth Assessment Report (AR5) of the Intergovernmental Panel on Climate Change (IPCC). First, a LULC change model was developed using RCP 4.5 and RCP 8.5 storylines and logistic regression. Three scenarios (climate change only, LULC change only, and climate and LULC change combined) were established, and the streamflow in future periods under these scenarios was simulated by the Soil and Water Assessment Tool (SWAT) model. Each scenario showed distinct seasonal variations in streamflow. Under climate change only, streamflow increased in spring and winter but decreased in summer and autumn, whereas LULC change increased high flow during wet periods but decreased low flow in dry periods. Although the LULC change had less effect than climate change on the changes in streamflow, the effect of LULC change on streamflow was significant. The result for the combined scenario was similar to that of the climate change only scenario, but with larger seasonal changes in streamflow. Although the effects of LULC change were smaller than those caused by climate change, LULC changes may heighten the problems of increased seasonal variability in streamflow caused by climate change. The results obtained in this study provide further insight into the availability of future streamflow and can aid in water resource management planning in the study area. Copyright © 2013 Elsevier B.V. All rights reserved.

  1. Analysis of occlusal contacts in different types of prosthodontic appliances, Eichner classifications, presence RCP-ICP slide and the type of occlusion.

    Science.gov (United States)

    Stipetić, J; Celebić, A; Baucić, I; Lazić, B; Komar, D; Bratolić, V; Catić, A; Stefancić, S

    2001-06-01

    The aim of the study was to determine the number and the type of the occlusal contacts (strong, weak) with respect to the type of the prosthodontic appliance (fixed, removable, combined fixed-removable) and with respect to the Eichner classification in patients with their appliances being in a good function for a long time. The aim of the study was also to determine the number and the type of the occlusal contacts (strong, weak) with respect to the type of occlusion (canine guided, group function or balanced) and the presence of the RCP-ICP slide. A total of 440 patients with different types of prosthodontic appliances were examined for the antagonistic occlusal contacts using occlusal strips of 11 microm and 50 microm. The average number of occlusal contacts was 10.5 for the upper and 10.46 for the lower posterior teeth, approximately 5 on each side of the tooth arch. The results of the study suggest that the biggest number of occlusal contacts were recorded for the small span fixed appliances (2 on average), the greater span fixed and fixed-removable prosthodontic appliances exhibited 1.6 occlusal contacts, and the removable complete denture exhibited 1.2 contact per the tooth in the posterior region. The number of the hard occlusal contacts was significantly greater in fixed and fixed-removable prosthodontic appliances in comparison with the complete dentures (p 0.05). The overall number of the occlusal contacts, as well as the number of the hard occlusal contacts was significantly greater in the Eichner class I cases (p 0.05). There was no significant difference in the number of occlusal contacts between the appliances with RCP-ICP slide and where ICP and RCP corresponded (p > 0.05).

  2. From land use to land cover: Restoring the afforestation signal in a coupled integrated assessment - earth system model and the implications for CMIP5 RCP simulations

    Energy Technology Data Exchange (ETDEWEB)

    Di Vittorio, Alan V. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Chini, Louise M. [Univ. of Maryland, College Park, MD (United States); Bond-Lamberty, Benjamin [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Mao, Jiafu [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Shi, Xiaoying [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Truesdale, John E. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Craig, Anthony P. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Calvin, Katherine V. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Jones, Andrew D. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Collins, William D. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Edmonds, James A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Hurtt, George [Univ. of Maryland, College Park, MD (United States); Thornton, Peter E. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Thomson, Allison M. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2014-11-27

    Climate projections depend on scenarios of fossil fuel emissions and land use change, and the IPCC AR5 parallel process assumes consistent climate scenarios across Integrated Assessment and Earth System Models (IAMs and ESMs). To facilitate consistency, CMIP5 used a novel land use harmonization to provide ESMs with seamless, 1500-2100 land use trajectories generated by historical data and four IAMs. However, we have identified and partially addressed a major gap in the CMIP5 land coupling design. The CMIP5 Community ESM (CESM) global afforestation is only 22% of RCP4.5 afforestation from 2005 to 2100. Likewise, only 17% of the Global Change Assessment Model’s (GCAM’s) 2040 RCP4.5 afforestation signal, and none of the pasture loss, were transmitted to CESM within a newly integrated model. This is a critical problem because afforestation is necessary for achieving the RCP4.5 climate stabilization. We attempted to rectify this problem by modifying only the ESM component of the integrated model, enabling CESM to simulate 66% of GCAM’s afforestation in 2040, and 94% of GCAM’s pasture loss as grassland and shrubland losses. This additional afforestation increases vegetation carbon gain by 19 PgC and decreases atmospheric CO2 gain by 8 ppmv from 2005 to 2040, implying different climate scenarios between CMIP5 GCAM and CESM. Similar inconsistencies likely exist in other CMIP5 model results, primarily because land cover information is not shared between models, with possible contributions from afforestation exceeding model-specific, potentially viable forest area. Further work to harmonize land cover among models will be required to adequately rectify this problem.

  3. DFH-3 Satellite Platform

    Institute of Scientific and Technical Information of China (English)

    RenShufang

    2005-01-01

    The DFH-3 satellite platform is designed and developed by China Academy of Space Technology (CAST). It is a medium capability communications satellite platform. The platform adopts threeaxis attitude stabilization control system, having solar array output power of 1.7kW by the end of its design lifetime of 8 years. Its mass is 2100kg with payload capacity of 220kg.

  4. Product Platform Replacements

    DEFF Research Database (Denmark)

    Sköld, Martin; Karlsson, Christer

    2012-01-01

    Purpose – It is argued in this article that too little is known about product platforms and how to deal with them from a manager's point of view. Specifically, little information exists regarding when old established platforms are replaced by new generations in R&D and production environments...... originality and value is achieved by focusing on product platform replacements believed to represent a growing management challenge....

  5. Rheem: Enabling Multi-Platform Task Execution

    KAUST Repository

    Agrawal, Divy

    2016-06-16

    Many emerging applications, from domains such as healthcare and oil & gas, require several data processing systems for complex analytics. This demo paper showcases Rheem, a framework that provides multi-platform task execution for such applications. It features a three-layer data processing abstraction and a new query optimization approach for multi-platform settings. We will demonstrate the strengths of Rheem by using real-world scenarios from three different applications, namely, machine learning, data cleaning, and data fusion. © 2016 ACM.

  6. The modeling of miniature UAV flight visualization simulation platform

    Science.gov (United States)

    Li, Dong-hui; Li, Xin; Yang, Le-le; Li, Xiong

    2015-12-01

    This paper combines virtual technology with visualization visual simulation theory, construct the framework of visual simulation platform, apply open source software FlightGear simulator combined with GoogleEarth design a small UAV flight visual simulation platform. Using software AC3D to build 3D models of aircraft and complete the model loading based on XML configuration, the design and simulation of visualization modeling visual platform is presented. By using model-driven and data transforming in FlightGear , the design of data transmission module is realized based on Visual Studio 2010 development platform. Finally combined with GoogleEarth it can achieve the tracking and display.

  7. The Creative Platform

    DEFF Research Database (Denmark)

    Byrge, Christian; Hansen, Søren

    This book is about introducing more creativity into general educational courses and cross-disciplinary activities. It is directed toward teachers at all levels in the educational system, but the Creative Platform is a general model, and thus the creative process will fundamentally be the same...... whether you consider thirdgrade teaching, human-resource development, or radical new thinking in product development in a company. The Creative Platform was developed at Aalborg University through a series of research-and-development activities in collaboration with educational institutions and private...... you can use in your work with the Creative Platform. This book is intended as an introduction on how to use the Creative Platform....

  8. Omnidirectional holonomic platforms

    Energy Technology Data Exchange (ETDEWEB)

    Pin, F.G.; Killough, S.M.

    1994-06-01

    This paper presents the concepts for a new family of wheeled platforms which feature full omnidirectionality with simultaneous and independently controlled rotational and translational motion capabilities. The authors first present the orthogonal-wheels concept and the two major wheel assemblies on which these platforms are based. They then describe how a combination of these assemblies with appropriate control can be used to generate an omnidirectional capability for mobile robot platforms. The design and control of two prototype platforms are then presented and their respective characteristics with respect to rotational and translational motion control are discussed.

  9. Steric Sea Level Change in Twentieth Century Historical Climate Simulation and IPCC-RCP8.5 Scenario Projection: A Comparison of Two Versions of FGOALS Model

    Institute of Scientific and Technical Information of China (English)

    DONG Lu; ZHOU Tianjun

    2013-01-01

    To reveal the steric sea level change in 20th century historical climate simulations and future climate change projections under the IPCC's Representative Concentration Pathway 8.5 (RCP8.5) scenario,the results of two versions of LASG/IAP's Flexible Global Ocean-Atmosphere-Land System model (FGOALS) are analyzed.Both models reasonably reproduce the mean dynamic sea level features,with a spatial pattern correlation coefficient of 0.97 with the observation.Characteristics of steric sea level changes in the 20th century historical climate simulations and RCP8.5 scenario projections are investigated.The results show that,in the 20th century,negative trends covered most parts of the global ocean.Under the RCP8.5 scenario,global-averaged steric sea level exhibits a pronounced rising trend throughout the 21st century and the general rising trend appears in most parts of the global ocean.The magnitude of the changes in the 21st century is much larger than that in the 20th century.By the year 2100,the global-averaged steric sea level anomaly is 18 cm and 10 cm relative to the year 1850 in the second spectral version of FGOALS (FGOALS-s2) and the second grid-point version of FGOALS (FGOALS-g2),respectively.The separate contribution of the thermosteric and halosteric components from various ocean layers is further evaluated.In the 20th century,the steric sea level changes in FGOALS-s2 (FGOALS-g2) are largely attributed to the thermosteric (halosteric) component relative to the pre-industrial control run.In contrast,in the 21st century,the thermosteric component,mainly from the upper 1000 m,dominates the steric sea level change in both models under the RCP8.5 scenario.In addition,the steric sea level change in the marginal sea of China is attributed to the thermosteric component.

  10. Framework and application of idle capacity integrated management based on GIS platform%基于GIS平台的储备容量集成管理框架与应用

    Institute of Scientific and Technical Information of China (English)

    栾殿龙; 张健; 王鹏橙

    2015-01-01

    Idle capacity management is one of the most important sections of power demand side management in power supply enterprises. And it is an important measure of extension services and increased interaction with power consumers. On the basis of previous study of power demand side management,due to inaccurate idle capacity information,it leads to many problems:the power grid planning of power supply enterprise and the actual demand of electricity do not match,electricity forecasting has distinctions,the installation of electron often overs time limit,the distribution of load is inequality and so on. Therefore,the power supply enterprise can control idle capacity by establishing the database of idle capacity information through the power GIS as the basic platform. In this way,power supply enterprises will realize information technology management in power demand side and improve their service level and their competitiveness.%供电企业对电力消费者进行管理时,由于储备容量的信息不准确,导致供电企业的电网规划与实际用电需求不符、用电量预测准确性存在偏差、报装接电周期长、电网电力负荷分配不均等问题。由此,供电企业以电力GIS为基础平台,建立储备容量信息库、对储备容量进行管理,是实现电力营销信息化管理的前提,也是供电企业提升服务水平和增强电力市场竞争能力的必要途径。

  11. Advanced offshore oil platforms

    Energy Technology Data Exchange (ETDEWEB)

    Ellers, F.S.

    1982-04-01

    Four innovative offshore platforms that are designed to withstand 100-foot waves in waters 600-feet deep are described. These platforms are: (1) Stratfjord B Concrete Gravity-Base Platform; (2) Magnus Steel-Template-Jacket Platform; (3) Hutton Tension-Leg Platform; and (4) Block 280 Guyed Tower. The Statfjord B platform, designed in Norway, rests on four massive concrete columns with storage tanks at the base. It depends solely on its own mass for stability. The Magnus platform, designed by the British, is the heaviest offshore platform yet fabricated, weighing 41,000 tons. Two of the platform's four legs will incorporate flotation chambers so that the structure can be floated to its site in the North Sea. The Hutton structure, also designed in England, will consist of a buoyant hull tethered to the sea floor by slender steel tubes at its four corners. The first platform of its type, the Hutton structure is also destined for the North Sea. The US designed Block 280 guyed tower is designed for service in the Gulf of Mexico in water 1000 feet deep. It will be pinned to the sea floor by a spokelike array of 20 steel cables, each one more than 3000 feet long. The tower and its guys will weigh 43,000 tons, slightly more than the Magnus steel-template jacket and more than four time as much as the Eiffel Tower. At a cost of approximately $2.6 billion, the Magnus is the most expensive offshore platform to date. The Statfjord B was put into production in 1982. The Magnus is scheduled for oil production in 1983. The Hutton and the Block 280 will both be producing in 1984. (JMT)

  12. Analysis of the Framework of Microsoft DNA

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Microsoft DNA(Distributed interNet Application) has p rovided a effective framework of combination PC with the Internet perfectly; In addition, this open framework hase also given the integration of multilingual co mponents a strong managing platform. This article has deeply analysed the main technologys of Microsoft DNA, involve COM basic technology, framework of DNA, Microfost UDA(Universal Data Access),com ponent management with COM+, asynchronous communication with MSMQ(M icrosoft Message Queue). In...

  13. Pro Zend Framework Techniques Building a Full CMA Using Advanced Aspects of the Zend Framework

    CERN Document Server

    Lyman, Forrest

    2009-01-01

    The Zend Framework is a truly amazing PHP-based web application development framework and platform that is breathing new life into PHP development. One of the most common uses for a framework such as this is to build content-driven web sites. Pro Zend Framework CMS offers * A structured guide for PHP developers, ultimately helping you to create more flexible software much more quickly * Clear guidance through the entire process of building a custom CMS with the Zend Framework* The ideal example project, building a CMS, to illustrate how to use the many different aspects of the framework What y

  14. 新能源装备研发设计服务平台业务模式及技术框架研究%Research on New Energy Equipment R&D Service Platform Business Mode and Technical Framework

    Institute of Scientific and Technical Information of China (English)

    张青雷; 徐欣; 郑茂宽; 明新国

    2015-01-01

    研发设计领域专业化分工越来越细 ,研发设计单位对共性服务资源的需求越来越强烈 ,信息技术的发展为研发设计服务化 ,尤其是资源共享与优化配置 ,以及任务协同作业提供了全新模式.在梳理研发设计服务现有研究的基础上 ,重点研究研发设计服务化基本模式与流程 ,依托新能源装备领域实例 ,梳理并搭建了应用于该领域研发设计服务平台的业务框架和技术框架.%With the development of specialized division in R&D area ,needs from R&D units for public service resources are growing greatly .The development of information technologies provides brand new business modes for R&D servitization , especially for resource sharing and optimized configuration .On the basis of existing researches ,basic business mode and workflow of R&D servitization are further studied .Then a systematic business mode and technical framework is construc-ted in the area of new energy equipment R&D to test and verify the research results .

  15. EURESCOM Services Platform

    NARCIS (Netherlands)

    Nieuwenhuis, Lambertus Johannes Maria; van Halteren, Aart

    1999-01-01

    This paper presents the results of the EURESCOM Project 715. In February 1999, a large team of researchers from six European public network operators completed a two year period of cooperative experiments on a TINA-based environment, called the EURESCOM Services Platform (ESP). This platform

  16. Enterprise ERP System Platform Integration Framework With FDSS Research and Application%企业ERP与FDSS系统平台集成框架的研究及应用

    Institute of Scientific and Technical Information of China (English)

    何源

    2015-01-01

    EAI system integration technology is widely used and it wil be a trend in the future.However,the integration in the enterprise management and financial decisions stil belongs to the innovative research and development stage.Theses can integrate the required information and resources in the unified architecture of the platform andrealize the seamless connection between ERP and FDDS effectively using the EAI system integration technology.Meanwhile,using the EAI system integration technology can integrate the distributed system technology of large enterprises,provide data synchronization and resource sharing for the enterprise efficiency,security and steadiness,realize the application system integration of large enterprises and the data sharing complementary characteristics between enterprise resource planning management and financial decision support.By using this achievement,the enterprise performance management and business decisions wil step to a new level.%EAI系统集成技术应用广泛,也是未来发展的一种趋势,但在企业经营管理与财务决策方面的集成尚属创新研发阶段。论文通过EAI系统集成技术,将所需信息资源集成于统一的架构平台中,有效地实现了ERP与FDDS两大系统的无缝链接;把大型企业分散的系统技术整合协同起来,为企业高效、安全稳固地提供数据同步与资源共享,实现大型企业应用系统集成,较好地解决了企业资源计划管理与财务决策支持的数据分享与特性互补。该项成果地应用,必定能使企业的绩效管理与经营决策迈上新台阶。

  17. ICW eHealth Framework.

    Science.gov (United States)

    Klein, Karsten; Wolff, Astrid C; Ziebold, Oliver; Liebscher, Thomas

    2008-01-01

    The ICW eHealth Framework (eHF) is a powerful infrastructure and platform for the development of service-oriented solutions in the health care business. It is the culmination of many years of experience of ICW in the development and use of in-house health care solutions and represents the foundation of ICW product developments based on the Java Enterprise Edition (Java EE). The ICW eHealth Framework has been leveraged to allow development by external partners - enabling adopters a straightforward integration into ICW solutions. The ICW eHealth Framework consists of reusable software components, development tools, architectural guidelines and conventions defining a full software-development and product lifecycle. From the perspective of a partner, the framework provides services and infrastructure capabilities for integrating applications within an eHF-based solution. This article introduces the ICW eHealth Framework's basic architectural concepts and technologies. It provides an overview of its module and component model, describes the development platform that supports the complete software development lifecycle of health care applications and outlines technological aspects, mainly focusing on application development frameworks and open standards.

  18. Monte Carlo modelling projects the loss of most land-terminating glaciers on Svalbard in the 21st century under RCP 8.5 forcing

    Science.gov (United States)

    Möller, Marco; Navarro, Francisco; Martín-Español, Alba

    2016-09-01

    The high Arctic archipelagos around the globe are among the most strongly glacierized landscapes on Earth apart from the Greenland and Antarctic ice sheets. Over the past decades, the mass losses from land ice in the high Arctic regions have contributed substantially to global sea level rise. Among these regions, the archipelago of Svalbard showed the smallest mass losses. However, this could change in the coming decades, as Svalbard is expected to be exposed to strong climate warming over the 21st century. Here we present extensive Monte Carlo simulations of the future ice-mass evolution of 29 individual land-terminating glaciers on the Svalbard archipelago under an RCP 8.5 climate forcing. An extrapolation of the 29 sample glaciers to all land-terminating glaciers of the archipelago suggests an almost complete deglaciation of the region by 2100. Under RCP 8.5, 98% of the land-terminating glaciers will have declined to less than one tenth of their initial size, resulting in a loss of 7392 ± 2481 km2 of ice coverage.

  19. 基于 Hadoop 的数值预报产品服务平台设计与实现%Design and Implementation of NWP Data Service Platform Based on Hadoop Framework

    Institute of Scientific and Technical Information of China (English)

    李永生; 曾沁; 徐美红; 石小英

    2015-01-01

    As the numerical weather prediction (NWP)products increase in huge amounts every day,traditional relational database has the problem of low efficiency in archiving capacity and management,while file based storage faces performance challenges in long-time-series data accessing and massive computation of spatial-temporal data.Therefore,a three-tier software framework is designed,which implements distribu-ted data storage model,parallel data access service and distributed computation for frequently used statisti-cal algorithms based on Hadoop framework. Meteorological big data such as NWP products,radar 3D mosaic and satellite remote sensing are de-signed to be composed of metadata and data entity,which both are stored in Hbase data tables,and man-aged with HDFS file system.Metadata are defined by variable name,dimension,latitude,longitude,alti-tude and lead time etc.,and data entity consists of row key,time stamp and column family to store the value at each grid point.A Rest (representational state transfer)Web Service is setup for direct NWP data acquisition,field data clipping and location based time-series accessing.File download services in “MI-CAPS”,“surfer”and “json”format are also ready for the third-party meteorological software.System tes-ting for data access of CHAF model shows that it costs only 12 seconds to write in 1000 NWP data fields each with 82503 grid points,and less than 4 seconds to read out the same amount of data from the distribu-ted databases. Map-reduce scheme are implemented for computation of meteorological algorithms,e.g.,Kalman fil-ter and successive regression.Most of meteorological statistical algorithms are time independent,which make it possible that a task is divided into small sub-tasks according to data slicing on time series,and as-signed to different computational nodes in map programs.Reduce programs are to gather and summarize the result of sub-task computation.With data amount and users increasing,Hadoop framework

  20. The Common HOL Platform

    OpenAIRE

    Adams, Mark

    2015-01-01

    The Common HOL project aims to facilitate porting source code and proofs between members of the HOL family of theorem provers. At the heart of the project is the Common HOL Platform, which defines a standard HOL theory and API that aims to be compatible with all HOL systems. So far, HOL Light and hol90 have been adapted for conformance, and HOL Zero was originally developed to conform. In this paper we provide motivation for a platform, give an overview of the Common HOL Platform's theory and...

  1. Ladder attachment platform

    Science.gov (United States)

    Swygert,; Richard, W [Springfield, SC

    2012-08-28

    A ladder attachment platform is provided that includes a base for attachment to a ladder that has first and second side rails and a plurality of rungs that extend between in a lateral direction. Also included is a user platform for having a user stand thereon that is carried by the base. The user platform may be positioned with respect to the ladder so that it is not located between a first plane that extends through the first side rail and is perpendicular to the lateral direction and a second plane that extends through the second side rail and is perpendicular to the lateral direction.

  2. Platform-based production development

    DEFF Research Database (Denmark)

    Bossen, Jacob; Brunoe, Thomas Ditlev; Nielsen, Kjeld

    2015-01-01

    Platforms as a means for applying modular thinking in product development is relatively well studied, but platforms in the production system has until now not been given much attention. With the emerging concept of platform-based co-development the importance of production platforms is though...... indisputable. This paper presents state-of-the-art literature on platform research related to production platforms and investigates gaps in the literature. The paper concludes on findings by proposing future research directions....

  3. USA Hire Testing Platform

    Data.gov (United States)

    Office of Personnel Management — The USA Hire Testing Platform delivers tests used in hiring for positions in the Federal Government. To safeguard the integrity of the hiring processes and ensure...

  4. MULTIFUNCTIONAL PLATFORMS AND

    African Journals Online (AJOL)

    Solar service centres and multifunctional platforms are innovative concepts for providing energy services in ... same time generate income. obeng ..... communities the driving force behind the ... operator(s) had to contact repairers outside their.

  5. The Common HOL Platform

    Directory of Open Access Journals (Sweden)

    Mark Adams

    2015-07-01

    Full Text Available The Common HOL project aims to facilitate porting source code and proofs between members of the HOL family of theorem provers. At the heart of the project is the Common HOL Platform, which defines a standard HOL theory and API that aims to be compatible with all HOL systems. So far, HOL Light and hol90 have been adapted for conformance, and HOL Zero was originally developed to conform. In this paper we provide motivation for a platform, give an overview of the Common HOL Platform's theory and API components, and show how to adapt legacy systems. We also report on the platform's successful application in the hand-translation of a few thousand lines of source code from HOL Light to HOL Zero.

  6. The Creative Platform

    DEFF Research Database (Denmark)

    Byrge, Christian; Hansen, Søren

    whether you consider thirdgrade teaching, human-resource development, or radical new thinking in product development in a company. The Creative Platform was developed at Aalborg University through a series of research-and-development activities in collaboration with educational institutions and private......This book is about introducing more creativity into general educational courses and cross-disciplinary activities. It is directed toward teachers at all levels in the educational system, but the Creative Platform is a general model, and thus the creative process will fundamentally be the same...... companies. It is a project in which the goal is to make a hands-on approach to a knowledge perspective on enhancing creativity. The underlying ambition of the Creative Platform is to make it easier to promote creativity. At www.uka.aau.dk/The+Creative+Platform, you can find extra materials and instructions...

  7. National Community Solar Platform

    Energy Technology Data Exchange (ETDEWEB)

    Rupert, Bart [Clean Energy Collective, Louisville, CO (United States)

    2016-06-30

    This project was created to provide a National Community Solar Platform (NCSP) portal known as Community Solar Hub, that is available to any entity or individual who wants to develop community solar. This has been done by providing a comprehensive portal to make CEC’s solutions, and other proven community solar solutions, externally available for everyone to access – making the process easy through proven platforms to protect subscribers, developers and utilities. The successful completion of this project provides these tools via a web platform and integration APIs, a wide spectrum of community solar projects included in the platform, multiple groups of customers (utilities, EPCs, and advocates) using the platform to develop community solar, and open access to anyone interested in community solar. CEC’s Incubator project includes web-based informational resources, integrated systems for project information and billing systems, and engagement with customers and users by community solar experts. The combined effort externalizes much of Clean Energy Collective’s industry-leading expertise, allowing third parties to develop community solar without duplicating expensive start-up efforts. The availability of this platform creates community solar projects that are cheaper to build and cheaper to participate in, furthering the goals of DOE’s SunShot Initiative. Final SF 425 Final SF 428 Final DOE F 2050.11 Final Report Narrative

  8. The Platformization of the Web: Making Web Data Platform Ready

    NARCIS (Netherlands)

    A. Helmond

    2015-01-01

    In this article, I inquire into Facebook’s development as a platform by situating it within the transformation of social network sites into social media platforms. I explore this shift with a historical perspective on, what I refer to as, platformization, or the rise of the platform as the dominant

  9. Implementing an enterprise search platform using Lucene.NET

    OpenAIRE

    Pettersson, Fredrik; Pettersson, Niklas

    2012-01-01

    This master’s thesis, conducted at Sectra Medical Systems AB, investigates the feasibility of integrating a search platform, built on modern search technology, into the complex architecture of existing products. This was done through the implementation and integration of a search platform prototype, called Sectra Enterprise Search. It was built upon the search engine library Lucene.NET, written in C# for the Microsoft .NET Framework. Lucene.NET originates from the Java library Lucene, which i...

  10. Platform Performance and Challenges - using Platforms in Lego Company

    DEFF Research Database (Denmark)

    Munk, Lone; Mortensen, Niels Henrik

    2009-01-01

    by the product defining users (product developers) and platform erosion. When the platforms are not used it is due to: unsuitable calculation models, lack of goals, rewards or benefits from management, unattractive tradeoffs and difficulties in understanding the platform. This indicates that platform design...... needs focus on the incentive of using the platform. This problem lacks attention in literature, as well as industry, where assessment criteria do not cover this aspect. Therefore, we recommend including user incentive in platform assessment criteria to these challenges. Concrete solution elements...... ensuring user incentive in platforms is an object for future research...

  11. Research on application system based on J2EE and Eclipse RCP%基于J2EE与Eclipse RCP的应用系统研究

    Institute of Scientific and Technical Information of China (English)

    郭盈; 耿莉

    2008-01-01

    Eclipse RCP (Rich Client Platform,富客户端平台)是基于Eclipse项目的一个开发富客户端应用程序的框架(如图1所示),它提供了一个通用的Eclipse工作台,允许开发人员扩建和构造强大的、跨平台的应用程序。开发人员可以定义应用程序外观、商标和其他Eclipse基础组件等,实现自己的桌面应用程序。目前,使用RCP开发的产品很多,

  12. Transactional Network Platform: Applications

    Energy Technology Data Exchange (ETDEWEB)

    Katipamula, Srinivas; Lutes, Robert G.; Ngo, Hung; Underhill, Ronald M.

    2013-10-31

    In FY13, Pacific Northwest National Laboratory (PNNL) with funding from the Department of Energy’s (DOE’s) Building Technologies Office (BTO) designed, prototyped and tested a transactional network platform to support energy, operational and financial transactions between any networked entities (equipment, organizations, buildings, grid, etc.). Initially, in FY13, the concept demonstrated transactions between packaged rooftop air conditioners and heat pump units (RTUs) and the electric grid using applications or "agents" that reside on the platform, on the equipment, on a local building controller or in the Cloud. The transactional network project is a multi-lab effort with Oakridge National Laboratory (ORNL) and Lawrence Berkeley National Laboratory (LBNL) also contributing to the effort. PNNL coordinated the project and also was responsible for the development of the transactional network (TN) platform and three different applications associated with RTUs. This document describes two applications or "agents" in details, and also summarizes the platform. The TN platform details are described in another companion document.

  13. Volttron: An Agent Platform for the Smart Grid

    Energy Technology Data Exchange (ETDEWEB)

    Haack, Jereme N.; Akyol, Bora A.; Carpenter, Brandon J.; Tews, Cody W.; Foglesong, Lance W.

    2013-05-06

    VOLLTRON platform enables the deployment of intelligent sensors and controllers in the smart grid and provides a stable, secure and flexible framework that expands the sensing and control capabilities. VOLTTRON platform provides services fulfilling the essential requirements of resource management and security for agent operation in the power grid. The facilities provided by the platform allow agent developers to focus on the implementation of their agent system and not on the necessary "plumbing' code. For example, a simple collaborative demand response application was written in less than 200 lines of Python.

  14. The Definitive Guide to NetBeans™ Platform 7

    CERN Document Server

    Bock, Heiko

    2011-01-01

    The NetBeans Platform is the world's only modular Swing application framework, used by very large organizations in mission-critical scenarios, such as at Boeing and Northrop Grumman, as well as in the financial sector and in the oil/gas industry. For these large customers in enterprises who are increasingly interested in Maven and OSGi, the book will have particular relevance. The Definitive Guide to NetBeans Platform 7 is a thorough and authoritative introduction to the open-source NetBeans Platform, covering all its major APIs in detail, with relevant code examples used throughout. * Provide

  15. Identification of platform levels

    DEFF Research Database (Denmark)

    Mortensen, Niels Henrik

    2005-01-01

    reduction, ability to launch a wider product portfolio without increasing resources and reduction of complexity within the whole company. To support the multiple product development process, platform based product development has in many companies such as Philips, VW, Ford etc. proven to be a very effective...... because the nature of developing platforms and applications are very different. In single product development reuse is often determined by individual designers, in multiple product development reuse is to a large degree a management issue. It is difficult for a company to switch from single to multiple...... development will be examined. Based on the identification of the above characteristics five platform levels are described. The research presented in this paper is a result of MSc, Ph.D projects at the Technical University of Denmark and consultancy projects within the organisation of Institute of Product...

  16. Geostationary multipurpose platforms

    Science.gov (United States)

    Bekey, I.; Bowman, R. M.

    1981-01-01

    In addition to the advantages generally associated with orbital platforms, such as improved reliability, economies of scale, simple connectivity of elements, reduced tracking demands and the restraint of orbital object population growth, geostationary platforms yield: (1) continuous access by fixed ground antennas for communications services; (2) continuous monitoring of phenomena over chosen regions of the earth's surface; (3) a preferred location for many solar-terrestrial physics experiments. The geostationary platform also offers a low-risk and economical solution to the impending saturation of the orbital arc/frequency spectrum, maximizing the capacity of individual slots and increasing the utility of the entire arc. It also allows the use of many small, simple and inexpensive earth stations through complexity inversion and high power per beam. Block diagram and operational flowcharts are provided.

  17. Platforms for antibiotic discovery.

    Science.gov (United States)

    Lewis, Kim

    2013-05-01

    The spread of resistant bacteria, leading to untreatable infections, is a major public health threat but the pace of antibiotic discovery to combat these pathogens has slowed down. Most antibiotics were originally isolated by screening soil-derived actinomycetes during the golden era of antibiotic discovery in the 1940s to 1960s. However, diminishing returns from this discovery platform led to its collapse, and efforts to create a new platform based on target-focused screening of large libraries of synthetic compounds failed, in part owing to the lack of penetration of such compounds through the bacterial envelope. This article considers strategies to re-establish viable platforms for antibiotic discovery. These include investigating untapped natural product sources such as uncultured bacteria, establishing rules of compound penetration to enable the development of synthetic antibiotics, developing species-specific antibiotics and identifying prodrugs that have the potential to eradicate dormant persisters, which are often responsible for hard-to-treat infections.

  18. Windows Azure Platform

    CERN Document Server

    Redkar, Tejaswi

    2011-01-01

    The Windows Azure Platform has rapidly established itself as one of the most sophisticated cloud computing platforms available. With Microsoft working to continually update their product and keep it at the cutting edge, the future looks bright - if you have the skills to harness it. In particular, new features such as remote desktop access, dynamic content caching and secure content delivery using SSL make the latest version of Azure a more powerful solution than ever before. It's widely agreed that cloud computing has produced a paradigm shift in traditional architectural concepts by providin

  19. Windows Azure Platform

    CERN Document Server

    Redkar, Tejaswi

    2010-01-01

    The Azure Services Platform is a brand-new cloud-computing technology from Microsoft. It is composed of four core components-Windows Azure, .NET Services, SQL Services, and Live Services-each with a unique role in the functioning of your cloud service. It is the goal of this book to show you how to use these components, both separately and together, to build flawless cloud services. At its heart Windows Azure Platform is a down-to-earth, code-centric book. This book aims to show you precisely how the components are employed and to demonstrate the techniques and best practices you need to know

  20. Wireless sensor platform

    Energy Technology Data Exchange (ETDEWEB)

    Joshi, Pooran C.; Killough, Stephen M.; Kuruganti, Phani Teja

    2017-08-08

    A wireless sensor platform and methods of manufacture are provided. The platform involves providing a plurality of wireless sensors, where each of the sensors is fabricated on flexible substrates using printing techniques and low temperature curing. Each of the sensors can include planar sensor elements and planar antennas defined using the printing and curing. Further, each of the sensors can include a communications system configured to encode the data from the sensors into a spread spectrum code sequence that is transmitted to a central computer(s) for use in monitoring an area associated with the sensors.

  1. Mobile4D platform

    CSIR Research Space (South Africa)

    Botha, Adèle

    2010-05-01

    Full Text Available . It is a communication platform that has architecture for creating, deploying and managing services and applications by integrating voice, video and data across a range of IP and telecom communication networks. In 2007, Red Hat made a firm commitment... based on the Mobicents muni ations Platform brand. 2.1.5  Telco specific User‐Generated Services   A variety of communication network operators have started initiatives to address User- Generated Services for the Telecom domain. Some...

  2. Model, Framework, and Platform of Health Persuasive Social Network

    Science.gov (United States)

    Al Ayubi, Soleh Udin

    2013-01-01

    Persuasive technology (PT) has the potential to support individuals to perform self-management and social support as a part of health behavior change. This has led a few researchers in the intersection of the areas of health behavior change and software engineering to apply behavior change and persuasion theories to software development practices,…

  3. NEAMS-IPL MOOSE Midyear Framework Activities

    Energy Technology Data Exchange (ETDEWEB)

    Permann, Cody [Idaho National Lab. (INL), Idaho Falls, ID (United States); Alger, Brian [Idaho National Lab. (INL), Idaho Falls, ID (United States); Peterson, John [Idaho National Lab. (INL), Idaho Falls, ID (United States); Slaughter, Andrew [Idaho National Lab. (INL), Idaho Falls, ID (United States); Andrš, David [Idaho National Lab. (INL), Idaho Falls, ID (United States); Martineau, Richard [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2017-05-09

    The MOOSE Framework is a modular pluggable framework for building complex simulations. The ability to add new objects with custom syntax is a core capability that makes MOOSE a powerful platform for coupling multiple applications together within a single environment. The creation of a new, more standardized JSON syntax output improves the external interfaces for generating graphical components or for validating input file syntax. The design of this interface and the requirements it satisfies are covered in this short report.

  4. Games and Platform Decisions

    DEFF Research Database (Denmark)

    Hansen, Poul H. Kyvsgård; Mikkola, Juliana Hsuan

    2007-01-01

    is the application of on-line games in order to provide training for decision makers and in order to generate overview over the implications of platform decisions. However, games have to be placed in a context with other methods and we argue that a mixture of games, workshops, and simulations can provide improved...

  5. Creative Platform Learning (CPL)

    DEFF Research Database (Denmark)

    Christensen, Jonna Langeland; Hansen, Søren

    Creative Platform Learning (CPL) er en pædagogisk metode, der skaber foretagsomme og innovative elever, der kan anvende deres kreativitet til at lære nyt. Ifølge den nye skolereform skal Innovation og entreprenørskab tydeliggøres i alle fag. I CPL er det en integreret del af undervisningen...

  6. Games and Platform Decisions

    DEFF Research Database (Denmark)

    Hansen, Poul H. Kyvsgård; Mikkola, Juliana Hsuan

    2007-01-01

    is the application of on-line games in order to provide training for decision makers and in order to generate overview over the implications of platform decisions. However, games have to be placed in a context with other methods and we argue that a mixture of games, workshops, and simulations can provide improved...

  7. Mobile Platforms and Development Environments

    CERN Document Server

    Helal, Sumi; Li, Wengdong

    2012-01-01

    Mobile platform development has lately become a technological war zone with extremely dynamic and fluid movement, especially in the smart phone and tablet market space. This Synthesis lecture is a guide to the latest developments of the key mobile platforms that are shaping the mobile platform industry. The book covers the three currently dominant native platforms -- iOS, Android and Windows Phone -- along with the device-agnostic HTML5 mobile web platform. The lecture also covers location-based services (LBS) which can be considered as a platform in its own right. The lecture utilizes a sampl

  8. A survey on platforms for big data analytics.

    Science.gov (United States)

    Singh, Dilpreet; Reddy, Chandan K

    The primary purpose of this paper is to provide an in-depth analysis of different platforms available for performing big data analytics. This paper surveys different hardware platforms available for big data analytics and assesses the advantages and drawbacks of each of these platforms based on various metrics such as scalability, data I/O rate, fault tolerance, real-time processing, data size supported and iterative task support. In addition to the hardware, a detailed description of the software frameworks used within each of these platforms is also discussed along with their strengths and drawbacks. Some of the critical characteristics described here can potentially aid the readers in making an informed decision about the right choice of platforms depending on their computational needs. Using a star ratings table, a rigorous qualitative comparison between different platforms is also discussed for each of the six characteristics that are critical for the algorithms of big data analytics. In order to provide more insights into the effectiveness of each of the platform in the context of big data analytics, specific implementation level details of the widely used k-means clustering algorithm on various platforms are also described in the form pseudocode.

  9. Future Projection of Storm Surge at Tokyo Bay under RCP 8.5 Scenario by Meteorological-Ocean-Tide Coupled Model

    Science.gov (United States)

    Iwamoto, T.; Nakamura, R.; Takagawa, T.; Shibayama, T.

    2016-12-01

    It is clearly valuable to accomplish well-reproduced storm surge model and conduct future projection for disaster prevention. In this study, the reproducibility of Meteorological-Ocean-Tide coupled model was validated by simulating typhoon Roke (2011) storm surge, which was recorded as the highest anomaly (119cm) at Tokyo tide station (JMA) in Tokyo Bay over the last 10 years. Furthermore, the future projection (2050) under global warming scenario (RCP8.5) was conducted. The coupled model was composed of 3 models; ARW-WRFV3 (Skamarock et al., 2008), FVCOM (Chen et al., 2011) and WXTide32. WRF firstly calculated downscaled meteorological field by using FiNal anaLysis (FNL) as initial/boundary (I/B) condition. In this calculation, single layer urban canopy model (Kusaka et al., 2001) and topography data from SRTM3 (90m mesh) and GSI (50m mesh) were applied. Then the output was used as I/B condition to FVCOM, which calculated storm surge. Finally tide level was calculated by adding storm surge to astronomical tide calculated by WXTide32. For 2050 case, sea surface temperature (SST) from 26 GCM under RCP8.5 was used for constructing pseudo global warming meteorological fields. In details, ensemble average of SST variation between 2006-2015 and 2041-2060 was added to FNL's SST by following Oya et al (2016). In this case, calculating astronomical tide is omitted due to the limitation of WXTide32. The reproduced result of typhoon Roke shows that the difference of maximum tide level (first peak) to the observation is less than 10cm, the difference of second peak is about 50cm. The future projection result shows that the increase of storm surge at Tokyo tide station is about 20cm and that at Funabashi is about 30cm. This intensification is mainly caused by wind speed increment, since the variation of low pressure due to higher SST is relatively small. Moreover, Funabashi is located in front of the open space at inner part of Tokyo Bay, Tokyo tide station is similar however

  10. Drivers of the tropospheric ozone budget throughout the 21st century under the medium-high climate scenario RCP 6.0

    Directory of Open Access Journals (Sweden)

    L. E. Revell

    2015-01-01

    Full Text Available Because tropospheric ozone is both a~greenhouse gas and harmful air pollutant, it is important to understand how anthropogenic activities may influence its abundance and distribution through the 21st century. Here, we present model simulations performed with the chemistry-climate model SOCOL, in which spatially disaggregated chemistry and transport tracers have been implemented in order to better understand the distribution and projected changes in tropospheric ozone. We examine the influences of ozone precursor emissions (nitrogen oxides (NOx, carbon monoxide (CO and volatile organic compounds (VOCs, climate change and stratospheric ozone recovery on the tropospheric ozone budget, in a~simulation following the climate scenario Representative Concentration Pathway (RCP 6.0. Changes in ozone precursor emissions have the largest effect, leading to a global-mean increase in tropospheric ozone which maximises in the early 21st century at 23%. The increase is most pronounced at northern midlatitudes, due to regional emission patterns: between 1990 and 2060, northern midlatitude tropospheric ozone remains at constantly large abundances: 31% larger than in 1960. Over this 70 year period, attempts to reduce emissions in Europe and North America do not have an effect on zonally-averaged northern midlatitude ozone because of increasing emissions from Asia, together with the longevity of ozone in the troposphere. A~simulation with fixed anthropogenic ozone precursor emissions of NOx, CO and non-methane VOCs at 1960 conditions shows a 6 % increase in global-mean tropospheric ozone, and an 11% increase at northern midlatitudes. This increase maximises in the 2080s, and is mostly caused by methane, which maximises in the 2080s following RCP 6.0, and plays an important role in controlling ozone directly, and indirectly through its influence on other VOCs and CO. Enhanced flux of ozone from the stratosphere to the troposphere as well as climate change

  11. AP1000核电站主泵的电气系统分析%Analysis of the RCP Electrical System of AP1000 Nuclear Power Plant

    Institute of Scientific and Technical Information of China (English)

    王宪坤

    2012-01-01

    AP1000 is the 3rd generation nuclear power plant imported from Westinghouse.It takes full advantage of passive techniques on the basis of safety coefficient enhancement,and it cancels the nuclear-grade active devices such as emergency diesel generator,decreases the operations by operators,and therefore decreases the human factor influences.It uses the minimum systems and equipment.and therefore simplifies the configuration.It adopts the advanced equipment that with long maintenance cycle or maintenance free,it decreases the interfaces of systems and equipment,enhances the safety response ability of the power plant to serious accidents or natural disasters.The RCP system is a key item for importing this technology due to its importance and particularity.It's to understand the configuration and special structure of the electric equipment by analyzing the function of RCP and the principle of electric system.%AP1000核电站在提高安全系数的基础上,充分利用大量的非能动技术,取消了应急柴油发电机等核级能动设备,减少了操作员的干预动作,降低了人因因素的影响。使用尽可能少的系统和设备,使得布置简化;采用了维修周期更长甚至免检修的先进设备,减少系统及设备之间的接口,提高了核电厂自身应对各种严重事故或自然灾害的安全响应能力。其中主泵系统由于它的重要性和特殊性,也是技术引进的重点项目;文章通过对主泵的作用和电气系统原理分析,阐述了电气设备的配置及特殊结构。

  12. Projections of Rainfall and Surface Temperature from CMIP5 Models under RCP4.5 and 8.5 over BIMSTEC Countries

    Science.gov (United States)

    Charan Pattnayak, Kanhu; Kar, Sarat Chandra; Kumari Pattnayak, Rashmita

    2015-04-01

    Rainfall and surface temperature are the most important climatic variables in the context of climate change. Thus, these variables simulated from fifth phase of the Climate Model Inter-comparison Project (CMIP5) models have been compared against Climatic Research Unit (CRU) observed data and projected for the twenty first century under the Representative Concentration Pathways (RCPs) 4.5 and 8.5 emission scenarios. Results for the seven countries under Bay of Bengal Initiative for Multi-Sectoral Technical and Economic Cooperation (BIMSTEC) such as Bangladesh, Bhutan, India, Myanmar, Nepal, Sri Lanka and Thailand have been examined. Six CMIP5 models namely GFDL-CM3, GFDL-ESM2M, GFDL-ESM2G, HadGEM2-AO, HadGEM2-CC and HadGEM2-ES have been chosen for this study. The study period has been considered is from 1861 to 2100. From this period, initial 145 years i.e. 1861 to 2005 is reference or historical period and the later 95 years i.e. 2005 to 2100 is projected period. The climate change in the projected period has been examined with respect to the reference period. In order to validate the models, the mean annual rainfall and temperature has been compared with CRU over the reference period 1901 to 2005. Comparison reveals that most of the models are able to capture the spatial distribution of rainfall and temperature over most of the regions of BIMSTEC countries. Therefore these model data can be used to study the future changes in the 21st Century. Four out six models shows that the rainfall over Central and North India, Thailand and eastern part of Myanmar shows decreasing trend and Bangladesh, Bhutan, Nepal and Sri Lanka shows an increasing trend in both RCP 4.5 and 8.5 scenarios. In case of temperature, all of the models show an increasing trend over all the BIMSTEC countries in both scenarios, however, the rate of increase is relatively less over Sri Lanka than the other countries. Annual cycles of rainfall and temperature over Bangladesh, Myanmar and Thailand

  13. Long Read Alignment with Parallel MapReduce Cloud Platform.

    Science.gov (United States)

    Al-Absi, Ahmed Abdulhakim; Kang, Dae-Ki

    2015-01-01

    Genomic sequence alignment is an important technique to decode genome sequences in bioinformatics. Next-Generation Sequencing technologies produce genomic data of longer reads. Cloud platforms are adopted to address the problems arising from storage and analysis of large genomic data. Existing genes sequencing tools for cloud platforms predominantly consider short read gene sequences and adopt the Hadoop MapReduce framework for computation. However, serial execution of map and reduce phases is a problem in such systems. Therefore, in this paper, we introduce Burrows-Wheeler Aligner's Smith-Waterman Alignment on Parallel MapReduce (BWASW-PMR) cloud platform for long sequence alignment. The proposed cloud platform adopts a widely accepted and accurate BWA-SW algorithm for long sequence alignment. A custom MapReduce platform is developed to overcome the drawbacks of the Hadoop framework. A parallel execution strategy of the MapReduce phases and optimization of Smith-Waterman algorithm are considered. Performance evaluation results exhibit an average speed-up of 6.7 considering BWASW-PMR compared with the state-of-the-art Bwasw-Cloud. An average reduction of 30% in the map phase makespan is reported across all experiments comparing BWASW-PMR with Bwasw-Cloud. Optimization of Smith-Waterman results in reducing the execution time by 91.8%. The experimental study proves the efficiency of BWASW-PMR for aligning long genomic sequences on cloud platforms.

  14. Long Read Alignment with Parallel MapReduce Cloud Platform

    Directory of Open Access Journals (Sweden)

    Ahmed Abdulhakim Al-Absi

    2015-01-01

    Full Text Available Genomic sequence alignment is an important technique to decode genome sequences in bioinformatics. Next-Generation Sequencing technologies produce genomic data of longer reads. Cloud platforms are adopted to address the problems arising from storage and analysis of large genomic data. Existing genes sequencing tools for cloud platforms predominantly consider short read gene sequences and adopt the Hadoop MapReduce framework for computation. However, serial execution of map and reduce phases is a problem in such systems. Therefore, in this paper, we introduce Burrows-Wheeler Aligner’s Smith-Waterman Alignment on Parallel MapReduce (BWASW-PMR cloud platform for long sequence alignment. The proposed cloud platform adopts a widely accepted and accurate BWA-SW algorithm for long sequence alignment. A custom MapReduce platform is developed to overcome the drawbacks of the Hadoop framework. A parallel execution strategy of the MapReduce phases and optimization of Smith-Waterman algorithm are considered. Performance evaluation results exhibit an average speed-up of 6.7 considering BWASW-PMR compared with the state-of-the-art Bwasw-Cloud. An average reduction of 30% in the map phase makespan is reported across all experiments comparing BWASW-PMR with Bwasw-Cloud. Optimization of Smith-Waterman results in reducing the execution time by 91.8%. The experimental study proves the efficiency of BWASW-PMR for aligning long genomic sequences on cloud platforms.

  15. Basin Assessment Spatial Planning Platform

    Energy Technology Data Exchange (ETDEWEB)

    2017-07-26

    The tool is intended to facilitate hydropower development and water resource planning by improving synthesis and interpretation of disparate spatial datasets that are considered in development actions (e.g., hydrological characteristics, environmentally and culturally sensitive areas, existing or proposed water power resources, climate-informed forecasts). The tool enables this capability by providing a unique framework for assimilating, relating, summarizing, and visualizing disparate spatial data through the use of spatial aggregation techniques, relational geodatabase platforms, and an interactive web-based Geographic Information Systems (GIS). Data are aggregated and related based on shared intersections with a common spatial unit; in this case, industry-standard hydrologic drainage areas for the U.S. (National Hydrography Dataset) are used as the spatial unit to associate planning data. This process is performed using all available scalar delineations of drainage areas (i.e., region, sub-region, basin, sub-basin, watershed, sub-watershed, catchment) to create spatially hierarchical relationships among planning data and drainages. These entity-relationships are stored in a relational geodatabase that provides back-end structure to the web GIS and its widgets. The full technology stack was built using all open-source software in modern programming languages. Interactive widgets that function within the viewport are also compatible with all modern browsers.

  16. Online stock trading platform

    Directory of Open Access Journals (Sweden)

    Ion LUNGU

    2006-01-01

    Full Text Available The Internet is the perfect tool that can assure the market’s transparency for any user who wants to trade on the stock market. The investor can have access to the market news, financial calendar or the press releases of the issuers. A good online trading platform also provides real-time intraday quotes, trading history and technical analysis giving the investor a clearer view of the supply and demand in the market. All this information provides the investor a good image of the market and encourages him to trade. This paper wishes to draft the pieces of an online trading platform and to analyze the impact of developing and implementing one in a brokerage firm.

  17. Available: motorised platform

    CERN Document Server

    The COMPASS collaboration

    2014-01-01

    The COMPASS collaboration would like to offer to a new owner the following useful and fully operational piece of equipment, which is due to be replaced with better adapted equipment.   Please contact Erwin Bielert (erwin.bielert@cern.ch or 160539) for further information.  Motorized platform (FOR FREE):   Fabricated by ACL (Alfredo Cardoso & Cia Ltd) in Portugal. The model number is MeXs 5-­‐30.  Specifications: 5 m wide, 1 m deep, adjustable height (1.5 m if folded). Maximum working floor height: 4 m. conforms to CERN regulations, number LV158. Type LD500, capacity 500 kg and weight 2000 kg.  If no interested party is found before December 2014, the platform will be thrown away.

  18. Common tester platform concept.

    Energy Technology Data Exchange (ETDEWEB)

    Hurst, Michael James

    2008-05-01

    This report summarizes the results of a case study on the doctrine of a common tester platform, a concept of a standardized platform that can be applicable across the broad spectrum of testing requirements throughout the various stages of a weapons program, as well as across the various weapons programs. The common tester concept strives to define an affordable, next-generation design that will meet testing requirements with the flexibility to grow and expand; supporting the initial development stages of a weapons program through to the final production and surveillance stages. This report discusses a concept investing key leveraging technologies and operational concepts combined with prototype tester-development experiences and practical lessons learned gleaned from past weapons programs.

  19. OGC Collaborative Platform undercover

    Science.gov (United States)

    Buehler, G.; Arctur, D. K.; Bermudez, L. E.

    2012-12-01

    The mission of the Open Geospatial Consortium (OGC) is to serve as a global forum for the collaboration of developers and users of spatial data products and services, and to advance the development of international standards for geospatial interoperability. The OGC coordinates with over 400 institutions in the development of geospatial standards. OGC has a dedicated staff supported by a Collaborative Web Platform to enable sophisticated and successful coordination among its members. Since its origins in the early 1990s, the OGC Collaborative Web Platform has evolved organically to be the collaboration hub for standards development in the exchange of geospatial and related types of information, among a global network of thousands of technical, scientific and management professionals spanning numerous disparate application domains. This presentation describes the structure of this collaboration hub, the relationships enabled (both among and beyond OGC members), and how this network fits in a broader ecosystem of technology development and information standards organizations.

  20. Cross-platform validation and analysis environment for particle physics

    CERN Document Server

    Chekanov, S V; Wilbern, D

    2015-01-01

    A multi-platform validation and analysis framework for public Monte Carlo simulation for high-energy particle collisions is discussed. The front-end of this framework uses the Python programming language, while the back-end is written in Java, which provides a multi-platform environment that can be run from a web browser and can easily be deployed at the grid sites. The analysis package includes all major software tools used in high-energy physics, such as Lorentz vectors, jet algorithms, histogram packages, graphic canvases, and tools for providing data access. This multi-platform software suite, designed to minimize OS-specific maintenance and deployment time, is used for online validation of Monte Carlo event samples through a web interface.

  1. Cross-platform validation and analysis environment for particle physics

    Energy Technology Data Exchange (ETDEWEB)

    Chekanov, S. V.; Pogrebnyak, I.; Wilbern, D.

    2017-01-01

    A multi-platform validation and analysis framework for public Monte Carlo simulation for high-energy particle collisions is discussed. The front-end of this framework uses the Python programming language, while the back-end is written in Java, which provides a multi-platform environment that can be run from a web browser and can easily be deployed at the grid sites. The analysis package includes all major software tools used in high-energy physics, such as Lorentz vectors, jet algorithms, histogram packages, graphic canvases, and tools for providing data access. This multi-platform software suite, designed to minimize OS-specific maintenance and deployment time, is used for online validation of Monte Carlo event samples through a web interface.

  2. Cloud Robotics Platforms

    Directory of Open Access Journals (Sweden)

    Busra Koken

    2015-01-01

    Full Text Available Cloud robotics is a rapidly evolving field that allows robots to offload computation-intensive and storage-intensive jobs into the cloud. Robots are limited in terms of computational capacity, memory and storage. Cloud provides unlimited computation power, memory, storage and especially collaboration opportunity. Cloud-enabled robots are divided into two categories as standalone and networked robots. This article surveys cloud robotic platforms, standalone and networked robotic works such as grasping, simultaneous localization and mapping (SLAM and monitoring.

  3. HPC - Platforms Penta Chart

    Energy Technology Data Exchange (ETDEWEB)

    Trujillo, Angelina Michelle [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-10-08

    Strategy, Planning, Acquiring- very large scale computing platforms come and go and planning for immensely scalable machines often precedes actual procurement by 3 years. Procurement can be another year or more. Integration- After Acquisition, machines must be integrated into the computing environments at LANL. Connection to scalable storage via large scale storage networking, assuring correct and secure operations. Management and Utilization – Ongoing operations, maintenance, and trouble shooting of the hardware and systems software at massive scale is required.

  4. IP Rights and Technological Platforms

    OpenAIRE

    Robert P. Merges

    2008-01-01

    This paper is about intellectual property rights (IPRs) and platform technologies. After a brief introduction explaining some basics of networks, standards and platforms, I turn to three policy issues. The first is the role of IP in what might be termed platform policies, the decisions by courts and regulators concerning whether and how to promote multi-party access to important digital platforms such as media player hardware, cell phones, PCs, and the like. I argue that for the most part the...

  5. A framework for assessing hydrological regime sensitivity to climate change in a convective rainfall environment: a case study of two medium-sized eastern Mediterranean catchments, Israel

    Directory of Open Access Journals (Sweden)

    N. Peleg

    2015-01-01

    Full Text Available A modeling framework is formulated and applied to assess the sensitivity of the hydrological regime of two catchments in a convective rainfall environment with respect to projected climate change. The study uses likely rainfall scenarios with high spatiotemporal resolution that are dependent on projected changes in the driving regional meteorological synoptic systems. The framework was applied to a case study in two medium-sized Mediterranean catchments in Israel, affected by convective rainfall, by combining the HiReS-WG rainfall generator and the SAC-SMA hydrological model. The projected climate change impact on the hydrological regime was examined for the RCP4.5 and RCP8.5 emission scenarios, comparing the historical (beginning of the 21st century and future (mid-21st-century periods from three general circulation model simulations available from CMIP5. Focusing on changes in the occurrence frequency of regional synoptic systems and their impact on rainfall and streamflow patterns, we find that the mean annual rainfall over the catchments is projected to be reduced by 15% (outer range 2–23% and 18% (7–25% for the RCP4.5 sand RCP8.5 emission scenarios, respectively. The mean annual streamflow volumes are projected to be reduced by 45% (10–60% and 47% (16–66%. The average events' streamflow volumes for a given event rainfall depth are projected to be lower by a factor of 1.4–2.1. Moreover, the streamflow season in these ephemeral streams is projected to be shorter by 22% and 26–28% for the RCP4.5 and RCP8.5, respectively. The amplification in reduction of streamflow volumes relative to rainfall amounts is related to the projected reduction in soil moisture, as a result of fewer rainfall events and longer dry spells between rainfall events during the wet season. The dominant factors for the projected reduction in rainfall amount were the reduction in occurrence of wet synoptic systems and the shortening of the wet synoptic systems

  6. "Platform switching": Serendipity

    Directory of Open Access Journals (Sweden)

    N Kalavathy

    2014-01-01

    Full Text Available Implant dentistry is the latest developing field in terms of clinical techniques, research, material science and oral rehabilitation. Extensive work is being done to improve the designing of implants in order to achieve better esthetics and function. The main drawback with respect to implant restoration is achieving good osseointegration along with satisfactory stress distribution, which in turn will improve the prognosis of implant prosthesis by reducing the crestal bone loss. Many concepts have been developed with reference to surface coating of implants, surgical techniques for implant placement, immediate and delayed loading, platform switching concept, etc. This article has made an attempt to review the concept of platform switching was in fact revealed accidentally due to the nonavailability of the abutment appropriate to the size of the implant placed. A few aspect of platform switching, an upcoming idea to reduce crestal bone loss have been covered. The various methods used for locating and preparing the data were done through textbooks, Google search and related articles.

  7. "Platform switching": serendipity.

    Science.gov (United States)

    Kalavathy, N; Sridevi, J; Gehlot, Roshni; Kumar, Santosh

    2014-01-01

    Implant dentistry is the latest developing field in terms of clinical techniques, research, material science and oral rehabilitation. Extensive work is being done to improve the designing of implants in order to achieve better esthetics and function. The main drawback with respect to implant restoration is achieving good osseointegration along with satisfactory stress distribution, which in turn will improve the prognosis of implant prosthesis by reducing the crestal bone loss. Many concepts have been developed with reference to surface coating of implants, surgical techniques for implant placement, immediate and delayed loading, platform switching concept, etc. This article has made an attempt to review the concept of platform switching was in fact revealed accidentally due to the nonavailability of the abutment appropriate to the size of the implant placed. A few aspect of platform switching, an upcoming idea to reduce crestal bone loss have been covered. The various methods used for locating and preparing the data were done through textbooks, Google search and related articles.

  8. The Prodiguer Messaging Platform

    Science.gov (United States)

    Denvil, S.; Greenslade, M. A.; Carenton, N.; Levavasseur, G.; Raciazek, J.

    2015-12-01

    CONVERGENCE is a French multi-partner national project designed to gather HPC and informatics expertise to innovate in the context of running French global climate models with differing grids and at differing resolutions. Efficient and reliable execution of these models and the management and dissemination of model output are some of the complexities that CONVERGENCE aims to resolve.At any one moment in time, researchers affiliated with the Institut Pierre Simon Laplace (IPSL) climate modeling group, are running hundreds of global climate simulations. These simulations execute upon a heterogeneous set of French High Performance Computing (HPC) environments. The IPSL's simulation execution runtime libIGCM (library for IPSL Global Climate Modeling group) has recently been enhanced so as to support hitherto impossible realtime use cases such as simulation monitoring, data publication, metrics collection, simulation control, visualizations … etc. At the core of this enhancement is Prodiguer: an AMQP (Advanced Message Queue Protocol) based event driven asynchronous distributed messaging platform. libIGCM now dispatches copious amounts of information, in the form of messages, to the platform for remote processing by Prodiguer software agents at IPSL servers in Paris. Such processing takes several forms: Persisting message content to database(s); Launching rollback jobs upon simulation failure; Notifying downstream applications; Automation of visualization pipelines; We will describe and/or demonstrate the platform's: Technical implementation; Inherent ease of scalability; Inherent adaptiveness in respect to supervising simulations; Web portal receiving simulation notifications in realtime.

  9. Platform computing powers enterprise grid

    CERN Multimedia

    2002-01-01

    Platform Computing, today announced that the Stanford Linear Accelerator Center is using Platform LSF 5, to carry out groundbreaking research into the origins of the universe. Platform LSF 5 will deliver the mammoth computing power that SLAC's Linear Accelerator needs to process the data associated with intense high-energy physics research (1 page).

  10. New Database Manipulation Tools in the Easy-Learning On-Line Platform

    Science.gov (United States)

    Radescu, Radu; Davidescu, Andrei; Pupezescu, Valentin

    2011-01-01

    The present paper deals with the new ORM (object-relational mapping) tool introduced in the easy-learning platform. Propel 1.5 is the latest version of Propel, one of the ORMs fully compatible with the Symfony framework, and in comparison with the older versions and it has drastically improved the way the easy-learning platform can manipulate its…

  11. An Integrated Platform for Dynamic Software Updating and its Application in Self-* systems

    DEFF Research Database (Denmark)

    Gregersen, Allan Raundahl; Jørgensen, Bo Nørregaard; Hadaytullah

    2012-01-01

    frameworks, component systems and application servers, Javeleon currently provides tight integration with the NetBeans Platform, facilitating dynamic updating for applications built on top of the NetBeans Platform in an unconstrained manner. Javeleon supports state-preserving unanticipated runtime evolution...

  12. REAL TIME DATA PROCESSING FRAMEWORKS

    Directory of Open Access Journals (Sweden)

    Yash Sakaria

    2015-09-01

    Full Text Available On a business level, everyone wants to get hold of the business value and other organizational advantages that big data has to offer. Analytics has arisen as the primitive path to business value from big data. Hadoop is not just a storage platform for big data; it’s also a computational and processing platform for business analytics. Hadoop is, however, unsuccessful in fulfilling business requirements when it comes to live data streaming. The initial architecture of Apache Hadoop did not solve the problem of live stream data mining. In summary, the traditional approach of big data being co-relational to Hadoop is false; focus needs to be given on business value as well. Data Warehousing, Hadoop and stream processing complement each other very well. In this paper, we have tried reviewing a few frameworks and products which use real time data streaming by providing modifications to Hadoop.

  13. Structure of recombinant capsids formed by the beta-annulus deletion mutant -- rCP (Delta48-59) of Sesbania mosaic virus.

    Science.gov (United States)

    Pappachan, Anju; Subashchandrabose, Chinnathambi; Satheshkumar, P S; Savithri, H S; Murthy, M R N

    2008-05-25

    A unique feature of several T=3 icosahedral viruses is the presence of a structure called the beta-annulus formed by extensive hydrogen bonding between protein subunits related by icosahedral three-fold axis of symmetry. This unique structure has been suggested as a molecular switch that determines the T=3 capsid assembly. In order to examine the importance of the beta-annulus, a deletion mutant of Sesbania mosaic virus coat protein in which residues 48-59 involved in the formation of the beta-annulus were deleted retaining the rest of the residues in the amino terminal segment (rCP (Delta48-59)) was constructed. When expressed in Escherichia coli, the mutant protein assembled into virus like particles of sizes close to that of the wild type virus particles. The purified capsids were crystallized and their three dimensional structure was determined at 3.6 A resolution by X-ray crystallography. The mutant capsid structure closely resembled that of the native virus particles. However, surprisingly, the structure revealed that the assembly of the particles has proceeded without the formation of the beta-annulus. Therefore, the beta-annulus is not essential for T=3 capsid assembly as speculated earlier and may be formed as a consequence of the particle assembly. This is the first structural demonstration that the virus particle morphology with and without the beta-annulus could be closely similar.

  14. Extensive nonhomologous meiotic synapsis between normal chromosome axes of an rcp(3;6)(p14;q21) translocation in a hairless Mexican boar.

    Science.gov (United States)

    Villagómez, D A F; Ayala-Valdovinos, M A; Galindo-García, J; Sánchez-Chipres, D R; Mora-Galindo, J; Taylor-Preciado, J J

    2008-01-01

    Due to its low fertility, expressed as small litter size, a Mexican hairless boar was subjected to cytogenetic investigation. Analysis of G-banded mitotic chromosomes revealed a reciprocal chromosome translocation, rcp(3;6) (p14;q21). Synaptonemal complex analysis showed a regular pairing behavior of the translocation chromosome axes, always resulting in a quadrivalent configuration. However, due to extensive nonhomologous pairing between the axes of nonderivative chromosomes 3 and 6, the quadrivalent mostly had an asymmetrical cross-shaped morphology. The nonhomologous pairing occurred not only at mid and late pachytene, but also at the earliest stage of pachytene. It seems that early pachytene heterosynapsis is a common phenomenon in the pairing behavior of pig reciprocal translocations. Therefore, heterosynapsis may reduce apoptosis of germ cells due to partial absence of homologous synapsis during the pairing phase of meiosis. The frequency of spermatocytes showing quadrivalent configurations with unpaired axial segments apparently did not affect germ cell progression in the boar, since fairly normal testicular histology was noticed. Copyright 2008 S. Karger AG, Basel.

  15. Thermal simulation for the chip model based on RCP package%基于RCP封装的芯片模型电热模拟

    Institute of Scientific and Technical Information of China (English)

    张路

    2015-01-01

    基于集成电路重分布封装技术(redistributed chip packaging,RCP)的发展,通过提取芯片封装体的具体参数,建立并优化了RCP芯片的热学模型.采用有限元的方法计算了该模型在一定热耗散功率下,施加不同风速条件时的温度分布情况,结果表明:强制对流条件的施加显著增强了RCP芯片封装体的散热能力,4m/s的风速可使其系统热阻降低58%,但是随着风速的增大,其影响不断减弱.所得出的具体风速与芯片结温的关系,可为RCP封装技术的散热设计提供有价值的参考.

  16. Future PMPs Estimation in Korea under AR5 RCP 8.5 Climate Change Scenario: Focus on Dew Point Temperature Change

    Science.gov (United States)

    Okjeong, Lee; Sangdan, Kim

    2016-04-01

    According to future climate change scenarios, future temperature is expected to increase gradually. Therefore, it is necessary to reflect the effects of these climate changes to predict Probable Maximum Precipitations (PMPs). In this presentation, PMPs will be estimated with future dew point temperature change. After selecting 174 major storm events from 1981 to 2005, new PMPs will be proposed with respect to storm areas (25, 100, 225, 400, 900, 2,025, 4,900, 10,000 and 19,600 km2) and storm durations (1, 2, 4, 6, 8, 12, 18, 24, 48 and 72 hours) using the Korea hydro-meteorological method. Also, orographic transposition factor will be applied in place of the conventional terrain impact factor which has been used in previous Korean PMPs estimation reports. After estimating dew point temperature using future temperature and representative humidity information under the Korea Meteorological Administration AR5 RCP 8.5, changes in the PMPs under dew point temperature change will be investigated by comparison with present and future PMPs. This research was supported by a grant(14AWMP-B082564-01) from Advanced Water Management Research Program funded by Ministry of Land, Infrastructure and Transport of Korean government.

  17. VOLTTRON: An Agent Execution Platform for the Electric Power System

    Energy Technology Data Exchange (ETDEWEB)

    Akyol, Bora A.; Haack, Jereme N.; Ciraci, Selim; Carpenter, Brandon J.; Vlachopoulou, Maria; Tews, Cody W.

    2012-06-05

    Volttron is an agent execution platform that is engineered for use in the electric power system. Volttron provides resource guarantees for agents and the platform including memory and processor utilization; authentication and authorization services; directory services for agent and resource location; and agent mobility. Unlike most other agent platforms, Volttron does not depend on a single agent authoring language. Instead, we chose to design and implement Volttron as a platform service and framework that is decoupled from the agent execution environment. A prototype implementation of Volttron has been written in Python (using Python v2.7.2) and we have executed agents written in Python and Java and as shell scripts. The intended use of Volttron is in the power distribution system for managing distributed generation, demand-response, and plug-in electric vehicles.

  18. Detailed Design of Intelligent Object Framework

    Directory of Open Access Journals (Sweden)

    Sasa Savicand Hao Shi

    2013-12-01

    Full Text Available The design and implementation of Intelligent Object Framework(IOF aims to unite the communication and device management through a platform independent ma nagement protocol in conjunction with a management application. The Core Framework is devel oped using Microsoft Visual Studio, Microsoft’s .NET Framework and Microsoft’s Windows Mobile SDK. Secondary Intelligent Object is developed using Tibbo Integrated Development Environment (TIDE and T-BASIC programming language that is loaded on an EM1026 Embedded Device Platform running Tibbo Op erating System (TiOS. The backend database is based on Microsoft’s SQL Server.In this paper, prot ocols associated with Smart Living are first reviewed.The system architecture and intelligent ob ject management studio are presented. Then device application design and database design are detailed . Finally conclusions are drawn and future work is addressed.

  19. The Geohazards Exploitation Platform

    Science.gov (United States)

    Laur, Henri; Casu, Francesco; Bally, Philippe; Caumont, Hervé; Pinto, Salvatore

    2016-04-01

    The Geohazards Exploitation Platform, or Geohazards TEP (GEP), is an ESA originated R&D activity of the EO ground segment to demonstrate the benefit of new technologies for large scale processing of EO data. This encompasses on-demand processing for specific user needs, systematic processing to address common information needs of the geohazards community, and integration of newly developed processors for scientists and other expert users. The platform supports the geohazards community's objectives as defined in the context of the International Forum on Satellite EO and Geohazards organised by ESA and GEO in Santorini in 2012. The GEP is a follow on to the Supersites Exploitation Platform (SSEP) an ESA initiative to support the Geohazards Supersites & Natural Laboratories initiative (GSNL). Today the GEP allows to exploit 70+ Terabyte of ERS and ENVISAT archive and the Copernicus Sentinel-1 data available on line. The platform has already engaged 22 European early adopters in a validation activity initiated in March 2015. Since September, this validation has reached 29 single user projects. Each project is concerned with either integrating an application, running on demand processing or systematically generating a product collection using an application available in the platform. The users primarily include 15 geoscience centres and universities based in Europe: British Geological Survey (UK), University of Leeds (UK), University College London (UK), ETH University of Zurich (CH), INGV (IT), CNR-IREA and CNR-IRPI (IT), University of L'Aquila (IT), NOA (GR), Univ. Blaise Pascal & CNRS (FR), Ecole Normale Supérieure (FR), ISTERRE / University of Grenoble-Alpes (FR). In addition, there are users from Africa and North America with the University of Rabat (MA) and the University of Miami (US). Furthermore two space agencies and four private companies are involved: the German Space Research Centre DLR (DE), the European Space Agency (ESA), Altamira Information (ES

  20. MVC Design Pattern for the multi framework distributed applications using XML, spring and struts framework

    OpenAIRE

    Praveen Gupta; Prof. M.C. Govil

    2010-01-01

    The model view controller (MVC) is a fundamental design pattern for the separation between user interface logic and business logic. Since applications are very large in size these days and the MVC designpattern can weak the coupling among the different application tiers of application. this paper presents a web application framework based on MVC in J2EE platform, and extends it with XML so that the framework is more flexible, expansible and easy to maintain. This is a multi tier system includ...

  1. Pro ASPNET MVC 3 Framework

    CERN Document Server

    Freeman, A

    2011-01-01

    The ASP.NET MVC 3 Framework is the latest evolution of Microsoft's ASP.NET web platform. It provides a high-productivity programming model that promotes cleaner code architecture, test-driven development, and powerful extensibility, combined with all the benefits of ASP.NET 4. In this third edition, the core model-view-controller (MVC) architectural concepts are not simply explained or discussed in isolation, but are demonstrated in action. You'll work through an extended tutorial to create a working e-commerce web application that combines ASP.NET MVC with the latest C# language features and

  2. Pro ASPNET MVC 2 Framework

    CERN Document Server

    Freeman, A

    2010-01-01

    The ASP.NET MVC 3 Framework is the latest evolution of Microsoft's ASP.NET web platform. It provides a radically new high-productivity programming model that promotes cleaner code architecture, test-driven development, and powerful extensibility, combined with all the benefits of ASP.NET 4. In this, third edition, the core model-view-controller (MVC) architectural concepts are not simply explained or discussed in isolation, but are demonstrated in action. You'll work through an extended tutorial to create a working e-commerce web application that combines ASP.NET MVC with the latest C# languag

  3. Identification of platform levels

    DEFF Research Database (Denmark)

    Mortensen, Niels Henrik

    2005-01-01

    reduction, ability to launch a wider product portfolio without increasing resources and reduction of complexity within the whole company. To support the multiple product development process, platform based product development has in many companies such as Philips, VW, Ford etc. proven to be a very effective...... and efficient tool. Transforming product development from single to multiple product development is a significant change in product development often involving major changes of product models, procedures and organization. In the area of product models a set of new models has to be introduced, e.g. models...

  4. Design and Implementation of the Information Management Platform of Wuxi River Chief Mechanism Based on the Spring Framework%基于Spring框架的无锡“河长制”信息管理平台的设计与实现

    Institute of Scientific and Technical Information of China (English)

    周吉; 李锡华; 徐洁文; 王浩渊; 陆菁; 许轶菁

    2016-01-01

    无锡“河长制”信息平台是以“河长制”管理体系为基础,将无锡两市七区的河道基础信息、管理流程、业务办理、统计分析、工作评价等环节信息进行梳理,借助互联网和移动互联网技术,实现无锡区域“河长制”的数字化管理。本文基于Spring框架,利用J2EE的B/S架构,实现市级和区级“河长办”的信息交互、业务联动和绩效评价等功能,同时对监控运营状态的关键性能指标(KPI 指标)管理,以及对生产经营过程中风险事件的预警和及时响应。系统具有良好的性能和稳定性,在河道信息管理中发挥了重要的作用。%Based on the River Chief Mechanism management system,the information platform conducts basic information,management process,business handling,statistical analysis,work evaluation and other aspects of the rivers in Wuxi.Through the technology of internet and mobile internet,the digital management of River Chief Mechanism in Wuxi has been achieved.Based on the Spring framework and J2EE B/S architecture,the system implements several functions among the municipal and district-level offices,such as information exchange,business interaction and performance evaluation. Additionally,the system can manage the key performance index(KPI index)of the operation state,and carry out early warning and in-time response to the risk events during the production and operation process.With good performance and stability,the system plays an important role in the information management of river channels.

  5. Framework for Mobile Payments Integration

    DEFF Research Database (Denmark)

    Carton, Fergal; Hedman, Jonas; Damsgaard, Jan

    2012-01-01

    basis for considering the contribution of mobile technologies to the payment industry. The framework is then used to describe the components of a mobile payments pilot project being run on a trial population of 250 students on a campus in Ireland. In this manner, weaknesses in the value proposition......This paper derives a theoretical framework for consideration of both the technologically driven dimensions of mobile payment solutions, and the associated value proposition for customers. Banks promote traditional payment instruments whose value proposition is the management of risk for both...... consumers and merchants. These instruments are centralised, costly and lack decision support functionality. The ubiquity of the mobile phone has provided a decentralised platform for managing payment processes in a new way, but the value proposition for customers has yet to be elaborated clearly...

  6. Instrument Remote Control Application Framework

    Science.gov (United States)

    Ames, Troy; Hostetter, Carl F.

    2006-01-01

    The Instrument Remote Control (IRC) architecture is a flexible, platform-independent application framework that is well suited for the control and monitoring of remote devices and sensors. IRC enables significant savings in development costs by utilizing extensible Markup Language (XML) descriptions to configure the framework for a specific application. The Instrument Markup Language (IML) is used to describe the commands used by an instrument, the data streams produced, the rules for formatting commands and parsing the data, and the method of communication. Often no custom code is needed to communicate with a new instrument or device. An IRC instance can advertise and publish a description about a device or subscribe to another device's description on a network. This simple capability of dynamically publishing and subscribing to interfaces enables a very flexible, self-adapting architecture for monitoring and control of complex instruments in diverse environments.

  7. An XML Driven Framework for Test Control and Data Analysis

    OpenAIRE

    2001-01-01

    An extensible, component-based framework has been developed at Fermilab to promote software reuse and provide a common platform for developing a family of test and data analysis systems. The framework allows for configuring applications from components through the use of XML configurations. It can be easily extended by adding new components and many application independent components are already provided with the framework. The core of the system has been developed in Java which guarantees it...

  8. Cots Correlator Platform

    Science.gov (United States)

    Schaaf, Kjeld; Overeem, Ruud

    2004-06-01

    Moore’s law is best exploited by using consumer market hardware. In particular, the gaming industry pushes the limit of processor performance thus reducing the cost per raw flop even faster than Moore’s law predicts. Next to the cost benefits of Common-Of-The-Shelf (COTS) processing resources, there is a rapidly growing experience pool in cluster based processing. The typical Beowulf cluster of PC’s supercomputers are well known. Multiple examples exists of specialised cluster computers based on more advanced server nodes or even gaming stations. All these cluster machines build upon the same knowledge about cluster software management, scheduling, middleware libraries and mathematical libraries. In this study, we have integrated COTS processing resources and cluster nodes into a very high performance processing platform suitable for streaming data applications, in particular to implement a correlator. The required processing power for the correlator in modern radio telescopes is in the range of the larger supercomputers, which motivates the usage of supercomputer technology. Raw processing power is provided by graphical processors and is combined with an Infiniband host bus adapter with integrated data stream handling logic. With this processing platform a scalable correlator can be built with continuously growing processing power at consumer market prices.

  9. Changes in the boreal summer intraseasonal oscillation projected by the CNRM-CM5 model under the RCP 8.5 scenario

    Science.gov (United States)

    Li, Jianying; Mao, Jiangyu

    2016-12-01

    The 30-60-day boreal summer intraseasonal oscillation (BSISO) is the predominant intraseasonal variability in the Asian summer monsoon (ASM) region, representing the canonical northward and northwestward propagating convective components over South Asia (SA) and East Asia/western North Pacific (EA/WNP) sectors in conjunction with eastward propagating convective anomalies. The objective of this study is to assess possible changes of the 30-60-day BSISO in future global warming condition by comparing the twentieth century simulation with the twenty-first century projection produced by the CNRM-CM5 model under the representative concentration pathway 8.5 (RCP 8.5) scenario. In response to the increase of sea surface temperature in the tropical and subtropical Indian and Pacific Oceans, the saturation specific humidity in the planetary boundary layer (PBL) increases by about 16 %, providing more moisture and moist static energy for tropical convection. Thus, the BSISO will be intensified, with large-amplitude events prevailing in a broader range of the Indo-Pacific region. The convective signal will initiate over more westward parts of the Indian Ocean and decay over the more eastward tropical Pacific. As the strengthening of northward propagations over the SA and EA/WNP sectors is intimately related to equatorial enhanced convective anomalies, the enhanced convective anomalies are accompanied by stronger ascents on the top of the PBL, together with the wetter seasonal-mean PBL background, resulting in stronger northward propagations through moisture mechanisms. Moreover, due to the increased moisture-holding capacity of the low-level atmosphere, the phase speeds of SASM and EA/WNP northward propagation will decrease.

  10. 反应堆冷却剂泵转速测量关键部件辐照试验设计%Design of Irradiation Experiment for Key Component of RCP Speed Measuring

    Institute of Scientific and Technical Information of China (English)

    吴茜; 邱建文

    2016-01-01

    核电厂RCP系统是压水堆核电厂的关键设备之一。主泵转速监测设备的主要作用是监测反应堆冷却剂泵的转速。主泵转速频率电流转换器作为主泵转速监测设备的关键部件,属于K2类鉴定要求范畴,需要完成辐照试验。本文根据核电站现场辐照条件及用户使用寿命的需求,对辐照试验的试验方案和试验环境进行了设计。试验结论表明,试验方案可行有效,经验证,该设备在安装现场辐照剂量率不大于15mSv/h的环境下,能够满足5年正常工作的可靠性要求。%RCP system of nuclear power plants is one of the key equipment of PWR nuclear power plant. the main role of the RCP speed monitoring device is to monitor RCP speed. The key component of the RCP speed frequency current converter as a RCP speed monitoring equipment, belonging to the K2 class of identification category, need to complete the irradiation test. Based on the irradiation conditions on site and the user needs, test programs and test environments of irradiation tests were designed. Conclusion of the test showed that the test is feasible and effective, it proves the equipment in the installation site can meet the reliability requirements of 5 years work properly under the environment is not greater than the radiation dose rate 15mSv/h.

  11. Communications payloads for geostationary platforms

    Science.gov (United States)

    Fordyce, S. W.

    1978-01-01

    Trends in communication satellites show increasing reuse of the frequency spectrum through multiple spot beams and orthogonal polarization, as well as consortia operation. Current reliance on orbital arc separation for frequency reuse may be inadequate for the projected traffic growth and the orbital slotting proposals before the ITU. This paper notes that cost advantages can accrue through common use of spacecraft subsystems and multiple users' platforms aboard a common geostationary platform. The rationale for such platforms is described and potential payloads are suggested.

  12. Utilizing platforms in industrialized construction

    DEFF Research Database (Denmark)

    Bonev, Martin; Wörösch, Michael; Hvam, Lars

    2015-01-01

    construction companies. A promising approach adapted by operations management and design theory regards individual building projects as the adjustment and recombination of components and processes from a set of predefined platforms, while configuration systems assure feasible building solutions. Design...... methods map structural platform characteristics so as to balance commonality and distinctiveness. Originality/value – This paper proposes a general theory of platform-based development and execution in the industrialised construction sector, which goes beyond concurrent approaches of standardising...

  13. Knowledge-Based Platform for Collaborative Innovation Development of Products

    Institute of Scientific and Technical Information of China (English)

    李莉敏; 唐文献; 方明伦; 杨延麟

    2005-01-01

    The platform of distributed design and resource sharing is important for medium-sized and small companies in developing products to improve competitiveness. As a background of creative product design, a knowledge model based on product collaborative innovation development of products (CIDP) is proposed. Characteristics of CIDP are analyzed, and the framework and key technologies of the CIDP-plafform based knowledge studied. Through integration of existing system and interface designs, a development platform has been built to support the PCID within knowledge-based engineering (KBE). An example is presented, indicating that the prototype system is maneuverable and practical.

  14. Design for Quick Evaluating Platform of Servo System Status

    Institute of Scientific and Technical Information of China (English)

    SHEN Huai-rong; NIU Ya-feng

    2006-01-01

    At present, the composite application platforms are seldom developed which can quickly evaluate the status and detect the faults of the major weapon equipment. According to the circumstances, the electro-hydraulic servo system is investigated, which is the very important component of the control system in the launch vehicle or missile. A quickly status evaluating technology for complex large equipment is researched. A composite application platform framework for the fault diagnosis and status evaluation of theservo system is devised. The result of the research can be extended to the application for other complex large equipment.

  15. Demand Analysis of Logistics Information Matching Platform: A Survey from Highway Freight Market in Zhejiang Province

    Science.gov (United States)

    Chen, Daqiang; Shen, Xiahong; Tong, Bing; Zhu, Xiaoxiao; Feng, Tao

    With the increasing competition in logistics industry and promotion of lower logistics costs requirements, the construction of logistics information matching platform for highway transportation plays an important role, and the accuracy of platform design is the key to successful operation or not. Based on survey results of logistics service providers, customers and regulation authorities to access to information and in-depth information demand analysis of logistics information matching platform for highway transportation in Zhejiang province, a survey analysis for framework of logistics information matching platform for highway transportation is provided.

  16. Web Platform Application

    Energy Technology Data Exchange (ETDEWEB)

    Paulsworth, Ashley [Sunvestment Group, Frederick, MD (United States); Kurtz, Jim [Sunvestment Group, Frederick, MD (United States); Brun de Pontet, Stephanie [Sunvestment Group, Frederick, MD (United States)

    2016-06-15

    Sunvestment Energy Group (previously called Sunvestment Group) was established to create a web application that brings together site hosts, those who will obtain the energy from the solar array, with project developers and funders, including affinity investors. Sunvestment Energy Group (SEG) uses a community-based model that engages with investors who have some affinity with the site host organization. In addition to a financial return, these investors receive non-financial value from their investments and are therefore willing to offer lower cost capital. This enables the site host to enjoy more savings from solar through these less expensive Community Power Purchase Agreements (CPPAs). The purpose of this award was to develop an online platform to bring site hosts and investors together virtually.

  17. Energy Tracking Software Platform

    Energy Technology Data Exchange (ETDEWEB)

    Ryan Davis; Nathan Bird; Rebecca Birx; Hal Knowles

    2011-04-04

    Acceleration has created an interactive energy tracking and visualization platform that supports decreasing electric, water, and gas usage. Homeowners have access to tools that allow them to gauge their use and track progress toward a smaller energy footprint. Real estate agents have access to consumption data, allowing for sharing a comparison with potential home buyers. Home builders have the opportunity to compare their neighborhood's energy efficiency with competitors. Home energy raters have a tool for gauging the progress of their clients after efficiency changes. And, social groups are able to help encourage members to reduce their energy bills and help their environment. EnergyIT.com is the business umbrella for all energy tracking solutions and is designed to provide information about our energy tracking software and promote sales. CompareAndConserve.com (Gainesville-Green.com) helps homeowners conserve energy through education and competition. ToolsForTenants.com helps renters factor energy usage into their housing decisions.

  18. The Creative Soccer Platform

    DEFF Research Database (Denmark)

    Johan Torp Rasmussen, Ludvig; Østergaard, Lars Domino

    2016-01-01

    Creativity is essential in soccer due to the unpredictable and complex situations occurring in the game, where stereotypical play gradually loses its efficiency. Further, creativity is an important psychological factor for the development of soccer expertise, and valuing creativity increases...... satisfaction and well-being. Although creative players are highly desired by coaches, the subject of cultivating creativity is mostly ignored and traditional training settings may even hamper the players' creativity. The purpose of this article is to introduce a novel approach for enhancing soccer players......' creativity, The Creative Soccer Platform (TCSP), and to demonstrate the implications of applying it in youth soccer practice, by means of soccer-specific creativity exercises. TCSP encompasses four theoretically based didactic principles (task focus, parallel thinking, horizontal thinking, and no experienced...

  19. Power Quality Indices Estimation Platform

    Directory of Open Access Journals (Sweden)

    Eliana I. Arango-Zuluaga

    2013-11-01

    Full Text Available An interactive platform for estimating the quality indices in single phase electric power systems is presented. It meets the IEEE 1459-2010 standard recommendations. The platform was developed in order to support teaching and research activities in electric power quality. The platform estimates the power quality indices from voltage and current signals using three different algorithms based on fast Fourier transform (FFT, wavelet packet transform (WPT and least squares method. The results show that the algorithms implemented are efficient for estimating the quality indices of the power and the platform can be used according to the objectives established. 

  20. Flexible experimental FPGA based platform

    DEFF Research Database (Denmark)

    Andersen, Karsten Holm; Nymand, Morten

    2016-01-01

    This paper presents an experimental flexible Field Programmable Gate Array (FPGA) based platform for testing and verifying digital controlled dc-dc converters. The platform supports different types of control strategies, dc-dc converter topologies and switching frequencies. The controller platform...... interface supporting configuration and reading of setup parameters, controller status and the acquisition memory in a simple way. The FPGA based platform, provides an easy way within education or research to use different digital control strategies and different converter topologies controlled by an FPGA...

  1. Product Platform Screening at LEGO

    DEFF Research Database (Denmark)

    Mortensen, Niels Henrik; Steen Jensen, Thomas; Nielsen, Ole Fiil

    2012-01-01

    Product platforms offer great benefits to companies developing new products in highly competitive markets. Literature describes how a single platform can be designed from a technical point of view, but rarely mentions how the process begins. How do companies identify possible platform candidates...... after a few changes had been applied to the initial process layout. This case study shows how companies must focus on a limited selection of simultaneous projects in order to keep focus. Primary stakeholders must be involved from the very beginning, and short presentations of the platform concepts...

  2. Platform evolution studies

    Science.gov (United States)

    Walton, Barbara A.

    1990-01-01

    The polar orbiting platform (POP), being developed by the Work Package 3 (WP3) Project at the Goddard Space Flight Center, will play a key role in the NASA Leadership Initiative, Mission to Planet Earth (MPE). It becomes, with the addition of payloads, an Earth observation satellite observatory. Mission to Planet Earth also has geostationary platforms (GEOP) as part of its global observational system. A study was begun in March 1988 to assess the applicability of the POP orbital replacement units (ORUs) for a geostationary Earth observing mission. Two test cases, representative of MPE payloads, were studied. Case A was used to emphasize the GEOP configuration and design; it used a Titan/Centaur to achieve orbit. Case B, considered to be much further in the future, included some assembly at the Space Station Freedom manned base and use of an orbital transfer vehicle to achieve orbit; requirements on the manned base to support such a mission were emphasized. The study found the POP systems more than adequate to meet GEOP requirements. Two types of changes were required for the POP ORUs: (1) modification to use only one surface for heat rejection; for the battery ORU, this meant 'opening up' the ORU to retain the radiator area with a corresponding decrease in depth; and (2) deletion of equipment not needed. The Case A configuration was shown to be within the planned capability of the Titan IV/Centaur. Assembly requirements were included for the Case B configuration, which is driven by the large microwave antennas of two of the payloads. The final review was April 19, 1989.

  3. ZEND FRAMEWORK

    Directory of Open Access Journals (Sweden)

    Lupasc Adrian

    2013-12-01

    Full Text Available In this paper we present Zend Architecture, which is an open source technology for developing web applications and services, based on object-oriented components, and the Model-View-Controller architectural pattern, also known as MVC, which is the fundament of this architecture. The MVC presentation emphasises its main characteristics, such as facilitating the components reuse by dividing the application into distinct interconnected modules, tasks distribution in the process of developing an application, the MVC life cycle and also the essential features of the components in which it separates the application: model, view, controller. The controller coordinates the models and views and it’s responsible with manipulating the user events through the corresponding actions. The model contains application rules, respectively the scripts that implement the database manipulation. The third component, the view represents the controllers interface with the user or the way it displays the response to the event triggered by the user. Another aspect treated in this paper consists in highlighting the Zend architecture advantages and disadvantages. Among the framework advantages, we can enumerate good code organization, due to its delimitation into three sections, presentation, logic and data access, and dividing the code into components, which facilitates the code reuse and testing. Other advantages are the open-source license and the support for multiple database systems. The main disadvantages are represented by its size and complexity, that makes it hard to understand for a beginner programmer, the resources it needs etc. The last section of the paper presents a comparison between Zend and other PHP architectures, like Symphony, CakePHP and CodeIgniter, which includes their essential features and points out their similarities and differences, based on the unique functions that set them apart from others. The main thing that distinguishes ZF from the

  4. Platform Performance and Challenges - using Platforms in Lego Company

    DEFF Research Database (Denmark)

    Munk, Lone; Mortensen, Niels Henrik

    2009-01-01

    This article studies the performance and challenges of using nine implemented product platforms in LEGO Company. Most of these do produce results, but do not meet their goals due to challenges in their usage in the daily product. The main challenges are that the platforms are not being used...

  5. CORBA-based platform for distributed multimedia applications

    Science.gov (United States)

    Blum, Christian; Molva, Refik

    1997-01-01

    As distributed multimedia applications are starting to be offered as services in enterprise and residential cable networks, there is a growing interest in platforms that provide a standard framework for the development and deployment of these applications. Key issues in platform design are service diversity, service portability and interoperability of user terminal equipment. We propose a platform architecture for the provision of multimedia communication services which logically separates application processing from media processing. Applications are installed in application pools from where they control a set of communicating multimedia terminals. Application-specific intelligence is downloaded into the terminals in the from of Tcl/Tk or Java scripts that generate graphical user interfaces, control media processing components, and communicate with the application in the pool. The platform architecture is based on CORBA and is defined as an extensible set of IDL interfaces for control and stream interfaces for multimedia communication. The platform architecture is based on CORBA and is defined as an extensible set of IDL interfaces for control and stream interfaces for multimedia communication. The platform supports applications development with high-level programming interfaces.

  6. Flexible Residential Smart Grid Simulation Framework

    Science.gov (United States)

    Xiang, Wang

    Different scheduling and coordination algorithms controlling household appliances' operations can potentially lead to energy consumption reduction and/or load balancing in conjunction with different electricity pricing methods used in smart grid programs. In order to easily implement different algorithms and evaluate their efficiency against other ideas, a flexible simulation framework is desirable in both research and business fields. However, such a platform is currently lacking or underdeveloped. In this thesis, we provide a simulation framework to focus on demand side residential energy consumption coordination in response to different pricing methods. This simulation framework, equipped with an appliance consumption library using realistic values, aims to closely represent the average usage of different types of appliances. The simulation results of traditional usage yield close matching values compared to surveyed real life consumption records. Several sample coordination algorithms, pricing schemes, and communication scenarios are also implemented to illustrate the use of the simulation framework.

  7. Rapid prototyping of robotic platforms

    CSIR Research Space (South Africa)

    De Ronde, Willis

    2016-11-01

    Full Text Available Building a robotic platform from raw materials can take anything from a few weeks to a few years to complete, depending on the complexity and size of the platform. This paper aims to introduce a novel approach of using abrasive waterjet machining...

  8. Preparing for a Product Platform

    DEFF Research Database (Denmark)

    Fiil-Nielsen, Ole; Munk, Lone; Mortensen, Niels Henrik

    2005-01-01

    they lead to increased sales due to more customized product as well as decreased costs due to reuse, making a product development platform a very profitable strategy for product developing companies. A successful implementation of a product development platform is not straightforward though...

  9. Product Platform Screening at LEGO

    DEFF Research Database (Denmark)

    Mortensen, Niels Henrik; Steen Jensen, Thomas; Nielsen, Ole Fiil

    2012-01-01

    Product platforms offer great benefits to companies developing new products in highly competitive markets. Literature describes how a single platform can be designed from a technical point of view, but rarely mentions how the process begins. How do companies identify possible platform candidates......, and how do they assess if these candidates have enough potential to be worth implementing? Danish toy manufacturer LEGO has systematically gone through this process twice. The first time the results were poor; almost all platform candidates failed. The second time, though, has been largely successful...... after a few changes had been applied to the initial process layout. This case study shows how companies must focus on a limited selection of simultaneous projects in order to keep focus. Primary stakeholders must be involved from the very beginning, and short presentations of the platform concepts...

  10. ADAPTABLE ALTERNATE REALITY GAMES PLATFORM

    Directory of Open Access Journals (Sweden)

    Liviu-Adrian Cotfas

    2013-12-01

    Full Text Available In this paper, we present an alternate reality games platform that facilitates the creation of ARG projects with different themes and sizes. The platform is well integrated with the most important social media networks, thus facilitating both the involvement of the public and the creation of a more engaging interaction for the participants. A cloud-based architecture was used in order to allow the platform to easily accommodate projects of various sizes and to provide a good level of scalability. The platform is fully localizable in any language and multiple languages can be used at once to create projects that target users from different countries. An initial project that uses gamification to create an immersive learning environment has been created around the developed platform. The project combines professional and public feedback in order to provide an enhanced learning experience.

  11. MVC Design Pattern for the multi framework distributed applications using XML, spring and struts framework

    Directory of Open Access Journals (Sweden)

    Praveen Gupta,

    2010-07-01

    Full Text Available The model view controller (MVC is a fundamental design pattern for the separation between user interface logic and business logic. Since applications are very large in size these days and the MVC designpattern can weak the coupling among the different application tiers of application. this paper presents a web application framework based on MVC in J2EE platform, and extends it with XML so that the framework is more flexible, expansible and easy to maintain. This is a multi tier system including presentation layer, business layer, data persistence layer and database layer. This separate codes, and improve maintainability and reusability of the application. In this paper, we implemented MVC using spring and struts framework. Our research study show that applying multiple framework to design theapplications using MVC concepts makes applications easier compare to a single framework.

  12. Paper based electronics platform

    KAUST Repository

    Nassar, Joanna Mohammad

    2017-07-20

    A flexible and non-functionalized low cost paper-based electronic system platform fabricated from common paper, such as paper based sensors, and methods of producing paper based sensors, and methods of sensing using the paper based sensors are provided. A method of producing a paper based sensor can include the steps of: a) providing a conventional paper product to serve as a substrate for the sensor or as an active material for the sensor or both, the paper product not further treated or functionalized; and b) applying a sensing element to the paper substrate, the sensing element selected from the group consisting of a conductive material, the conductive material providing contacts and interconnects, sensitive material film that exhibits sensitivity to pH levels, a compressible and/or porous material disposed between a pair of opposed conductive elements, or a combination of two of more said sensing elements. The method of sensing can further include measuring, using the sensing element, a change in resistance, a change in voltage, a change in current, a change in capacitance, or a combination of any two or more thereof.

  13. Health-e-Child a grid platform for european paediatrics

    CERN Document Server

    Skaburskas, K; Shade, J; Manset, D; Revillard, J; Rios, A; Anjum, A; Branson, A; Bloodsworth, P; Hauer, T; McClatchey, R; Rogulin, D

    2008-01-01

    The Health-e-Child (HeC) project [1], [2] is an EC Framework Programme 6 Integrated Project that aims to develop a grid-based integrated healthcare platform for paediatrics. Using this platform biomedical informaticians will integrate heterogeneous data and perform epidemiological studies across Europe. The resulting Grid enabled biomedical information platform will be supported by robust search, optimization and matching techniques for information collected in hospitals across Europe. In particular, paediatricians will be provided with decision support, knowledge discovery and disease modelling applications that will access data in hospitals in the UK, Italy and France, integrated via the Grid. For economy of scale, reusability, extensibility, and maintainability, HeC is being developed on top of an EGEE/gLite [3] based infrastructure that provides all the common data and computation management services required by the applications. This paper discusses some of the major challenges in bio-medical data integr...

  14. Design of the smart scenic spot service platform

    Science.gov (United States)

    Yin, Min; Wang, Shi-tai

    2015-12-01

    With the deepening of the smart city construction, the model "smart+" is rapidly developing. Guilin, the international tourism metropolis fast constructing need smart tourism technology support. This paper studied the smart scenic spot service object and its requirements. And then constructed the smart service platform of the scenic spot application of 3S technology (Geographic Information System (GIS), Remote Sensing (RS) and Global Navigation Satellite System (GNSS)) and the Internet of things, cloud computing. Based on Guilin Seven-star Park scenic area as an object, this paper designed the Seven-star smart scenic spot service platform framework. The application of this platform will improve the tourists' visiting experience, make the tourism management more scientifically and standardly, increase tourism enterprises operating earnings.

  15. Plat_Forms -- a contest: The web development platform comparison

    CERN Document Server

    Prechelt, Lutz

    2008-01-01

    "Plat_Forms" is a competition in which top-class teams of three programmers compete to implement the same requirements for a web-based system within 30 hours, each team using a different technology platform (Java EE, .NET, PHP, Perl, Python, or Ruby on Rails). The results will provide new insights into the real (rather than purported) pros, cons, and emergent properties of each platform. The evaluation will analyze many aspects of each solution, both external (usability, functionality, reliability, performance, etc.) and internal (structure, understandability, flexibility, etc.).

  16. Platform projections, compilers, interpreters and portability

    NARCIS (Netherlands)

    Bergstra, J.A.; Loots, M.E.

    1999-01-01

    Platform projection semantics extends projection semantics by means of the encapsulation of a processor used for program execution. Platform projection semantics abstracts from platform specific details. For a given program its platform projection semantics may be platform-independent. Two forms

  17. An Object Oriented and High Performance Platform for Aerothermodynamics Simulation

    OpenAIRE

    Lani, Andrea

    2008-01-01

    This thesis presents the author's contribution to the design and implementation of COOLFluiD,an object oriented software platform for the high performance simulation of multi-physics phenomena on unstructured grids. In this context, the final goal has been to provide a reliable tool for handling high speed aerothermodynamic applications. To this end, we introduce a number of design techniques that have been developed in order to provide the framework with flexibilityand reusability, allowing ...

  18. Vertical Relationships within Platform Marketplaces

    Directory of Open Access Journals (Sweden)

    Mark J. Tremblay

    2016-07-01

    Full Text Available In two-sided markets a platform allows consumers and sellers to interact by creating sub-markets within the platform marketplace. For example, Amazon has sub-markets for all of the different product categories available on its site, and smartphones have sub-markets for different types of applications (gaming apps, weather apps, map apps, ridesharing apps, etc.. The network benefits between consumers and sellers depend on the mode of competition within the sub-markets: more competition between sellers lowers product prices, increases the surplus consumers receive from a sub-market, and makes platform membership more desirable for consumers. However, more competition also lowers profits for a seller which makes platform membership less desirable for a seller and reduces seller entry and the number of sub-markets available on the platform marketplace. This dynamic between seller competition within a sub-market and agents’ network benefits leads to platform pricing strategies, participation decisions by consumers and sellers, and welfare results that depend on the mode of competition. Thus, the sub-market structure is important when investigating platform marketplaces.

  19. Knowledge Framework Implementation with Multiple Architectures - 13090

    Energy Technology Data Exchange (ETDEWEB)

    Upadhyay, H.; Lagos, L.; Quintero, W.; Shoffner, P. [Applied Research Center, Florida International University, Miami, FL 33174 (United States); DeGregory, J. [Office of D and D and Facility Engineering, Environmental Management, Department of Energy (United States)

    2013-07-01

    Multiple kinds of knowledge management systems are operational in public and private enterprises, large and small organizations with a variety of business models that make the design, implementation and operation of integrated knowledge systems very difficult. In recent days, there has been a sweeping advancement in the information technology area, leading to the development of sophisticated frameworks and architectures. These platforms need to be used for the development of integrated knowledge management systems which provides a common platform for sharing knowledge across the enterprise, thereby reducing the operational inefficiencies and delivering cost savings. This paper discusses the knowledge framework and architecture that can be used for the system development and its application to real life need of nuclear industry. A case study of deactivation and decommissioning (D and D) is discussed with the Knowledge Management Information Tool platform and framework. D and D work is a high priority activity across the Department of Energy (DOE) complex. Subject matter specialists (SMS) associated with DOE sites, the Energy Facility Contractors Group (EFCOG) and the D and D community have gained extensive knowledge and experience over the years in the cleanup of the legacy waste from the Manhattan Project. To prevent the D and D knowledge and expertise from being lost over time from the evolving and aging workforce, DOE and the Applied Research Center (ARC) at Florida International University (FIU) proposed to capture and maintain this valuable information in a universally available and easily usable system. (authors)

  20. Context Management Platform for Tourism Applications

    Science.gov (United States)

    Buján, David; Martín, David; Torices, Ortzi; López-de-Ipiña, Diego; Lamsfus, Carlos; Abaitua, Joseba; Alzua-Sorzabal, Aurkene

    2013-01-01

    The notion of context has been widely studied and there are several authors that have proposed different definitions of context. However, context has not been widely studied in the framework of human mobility and the notion of context has been imported directly from other computing fields without specifically addressing the tourism domain requirements. In order to store and manage context information a context data model and a context management platform are needed. Ontologies have been widely used in context modelling, but many of them are designed to be applied in general ubiquitous computing environments, do not contain specific concepts related to the tourism domain or some approaches do not contain enough concepts to represent context information related to the visitor on the move. That is why we propose a new approach to provide a better solution to model context data in tourism environments, adding more value to our solution reusing data about tourist resources from an Open Data repository and publishing it as Linked Data. We also propose the architecture for a context information management platform based on this context data model. PMID:23797739

  1. Context management platform for tourism applications.

    Science.gov (United States)

    Buján, David; Martín, David; Torices, Ortzi; López-de-Ipiña, Diego; Lamsfus, Carlos; Abaitua, Joseba; Alzua-Sorzabal, Aurkene

    2013-06-24

    The notion of context has been widely studied and there are several authors that have proposed different definitions of context. However, context has not been widely studied in the framework of human mobility and the notion of context has been imported directly from other computing fields without specifically addressing the tourism domain requirements. In order to store and manage context information a context data model and a context management platform are needed. Ontologies have been widely used in context modelling, but many of them are designed to be applied in general ubiquitous computing environments, do not contain specific concepts related to the tourism domain or some approaches do not contain enough concepts to represent context information related to the visitor on the move. That is why we propose a new approach to provide a better solution to model context data in tourism environments, adding more value to our solution reusing data about tourist resources from an Open Data repository and publishing it as Linked Data. We also propose the architecture for a context information management platform based on this context data model.

  2. Platform decisions supported by gaming

    DEFF Research Database (Denmark)

    Hansen, Poul H. Kyvsgård; Mikkola, Juliana Hsuan

    2007-01-01

    Platform is an ambiguous multidisciplinary concept. The philosophy behind it is easy to communicate and makes intuitively sense. However, the ease in communication does overshadow the high complexity when the concept is implemented. The practical industrial platform implementation challenge can...... is the application of on-line games in order to provide training for decision makers and in order to generate overview over the implications of platform decisions. However, games have to be placed in a context with other methods and we argue that a mixture of games, workshops, and simulations can provide improved...

  3. Changes of High Temperature Events During Rice Growth Period in MLRYR Under RCP Scenarios%RCP情景下长江中下游地区水稻生育期内高温事件的变化特征

    Institute of Scientific and Technical Information of China (English)

    冯灵芝; 熊伟; 居辉; 曹阳; 杨笛

    2015-01-01

    基于1981-2009年历史气象数据和全球气候模式HadGEM2-ES输出的未来2021-2050年RCP气候情景数据,采用日最高温度大于35℃的高温日数(HSD)、高温最长持续日数(MCD)和高温有效积温(HDD),分析过去和未来长江中下游地区水稻生育期高温事件频率、持续时间和强度的变化特征。结果表明:1981-2009年,长江中下游地区水稻生育期内温度升高,各高温指标均一致显著增加,Tmax(平均日最高气温)、HSD、MCD、HDD的气候倾向率分别为0.51℃·10a−1,3.9d·10a−1,0.6d·10a−1和8.2℃·d·10a−1,空间上表现为由北向南递增。除MCD外,Tmax、HSD和HDD均在2001-2002年发生由少到多的突变。2021-2050年两种RCP情景下,长江中下游大部分地区水稻生育期间日最高气温持续升高,高温日数增多,持续时间延长,高温强度增强。RCP2.6情景下,水稻生育期内Tmax、HSD、MCD、HDD较基准时段(1981-2009年)分别增加1.5℃、11.3d、5.6d和45.3℃·d,RCP8.5情景下分别增加1.7℃、15.4d、6.2d和61.1℃·d,且各高温事件在高值区的概率进一步加大。各指标的空间变化特征具有差异性,Tmax、HSD和MCD的增加幅度由东南向西北递增,湖南西部和江苏北部等基准期温度相对较低的地区增幅更大,而 HDD 的增幅以中部地区较大。湖北、安徽、湖南和江西中北部是未来高温事件频率、持续时间和强度均大幅增加的地区,防灾减灾工作严峻,需采取调整水稻播期,更替耐高温品种等措施减轻高温对水稻的危害。%Based on historical weather data from 1981 to 2009 and future climate data generated by HadGEM2-ES simulation with RCP2.6 and RCP8.5 emission scenarios from 2021 to 2050, frequency, duration and intensity of high temperature events during rice growth period in middle and lower reaches of Yangtze River (MLRYR) were analyzed by heat stress days (HSD

  4. Selecting Observation Platforms for Optimized Anomaly Detectability under Unreliable Partial Observations

    Energy Technology Data Exchange (ETDEWEB)

    Wen-Chiao Lin; Humberto E. Garcia; Tae-Sic Yoo

    2011-06-01

    Diagnosers for keeping track on the occurrences of special events in the framework of unreliable partially observed discrete-event dynamical systems were developed in previous work. This paper considers observation platforms consisting of sensors that provide partial and unreliable observations and of diagnosers that analyze them. Diagnosers in observation platforms typically perform better as sensors providing the observations become more costly or increase in number. This paper proposes a methodology for finding an observation platform that achieves an optimal balance between cost and performance, while satisfying given observability requirements and constraints. Since this problem is generally computational hard in the framework considered, an observation platform optimization algorithm is utilized that uses two greedy heuristics, one myopic and another based on projected performances. These heuristics are sequentially executed in order to find best observation platforms. The developed algorithm is then applied to an observation platform optimization problem for a multi-unit-operation system. Results show that improved observation platforms can be found that may significantly reduce the observation platform cost but still yield acceptable performance for correctly inferring the occurrences of special events.

  5. Geospatial Data Management Platform for Urban Groundwater

    Science.gov (United States)

    Gaitanaru, D.; Priceputu, A.; Gogu, C. R.

    2012-04-01

    Due to the large amount of civil work projects and research studies, large quantities of geo-data are produced for the urban environments. These data are usually redundant as well as they are spread in different institutions or private companies. Time consuming operations like data processing and information harmonisation represents the main reason to systematically avoid the re-use of data. The urban groundwater data shows the same complex situation. The underground structures (subway lines, deep foundations, underground parkings, and others), the urban facility networks (sewer systems, water supply networks, heating conduits, etc), the drainage systems, the surface water works and many others modify continuously. As consequence, their influence on groundwater changes systematically. However, these activities provide a large quantity of data, aquifers modelling and then behaviour prediction can be done using monitored quantitative and qualitative parameters. Due to the rapid evolution of technology in the past few years, transferring large amounts of information through internet has now become a feasible solution for sharing geoscience data. Furthermore, standard platform-independent means to do this have been developed (specific mark-up languages like: GML, GeoSciML, WaterML, GWML, CityML). They allow easily large geospatial databases updating and sharing through internet, even between different companies or between research centres that do not necessarily use the same database structures. For Bucharest City (Romania) an integrated platform for groundwater geospatial data management is developed under the framework of a national research project - "Sedimentary media modeling platform for groundwater management in urban areas" (SIMPA) financed by the National Authority for Scientific Research of Romania. The platform architecture is based on three components: a geospatial database, a desktop application (a complex set of hydrogeological and geological analysis

  6. NASA's geostationary communications platform program

    Science.gov (United States)

    Ramler, J.; Durrett, R.

    1984-01-01

    This paper reviews recent trends in communications satellites and explains NASA's current interest in geostationary communications platforms. Large communications platforms capable of supporting multiple payloads with common utilities have been examined in a number of studies since 1974 and appear to offer a number of potential advantages. In 1981, an Industry Briefing and Workshop sponsord by NASA focused on the institutional, operational and technical issues that will influence the implementation of geostationary platforms. The workshop identified numerous issues and problem areas that needed more detailed study. To address the issues/problems identified, a NASA geostationary communications platform program has been developed. This program is described, focusing on the initial studies to be performed.

  7. Platform attitude data acquisition system

    Digital Repository Service at National Institute of Oceanography (India)

    Afzulpurkar, S.

    A system for automatic acquisition of underwater platform attitude data has been designed, developed and tested in the laboratory. This is a micro controller based system interfacing dual axis inclinometer, high-resolution digital compass...

  8. Elevated Fixed Platform Test Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Elevated Fixed Platform (EFP) is a helicopter recovery test facility located at Lakehurst, NJ. It consists of a 60 by 85 foot steel and concrete deck built atop...

  9. Platforms for Innovation and Internationalization

    DEFF Research Database (Denmark)

    Rasmussen, Erik Stavnsager; Petersen, Nicolaj Hannesbo

    2017-01-01

    The high-tech global startup has many challenges related to both innovation and internationalization. From a Danish cluster of Welfare Tech firms, eight innovative and international firms were selected and interviewed. Such firms typically have to be agile and operate in virtual networks in almost...... all parts of their value chains. This article contributes to the understanding of how innovation and internationalization to a great extent are interlinked. The firms have developed a core product or service offering, which the firms often describe as “a platform”. Around the platform, they develop...... their products and services for new customers and users in new countries. The firms have to sustain a strong focus on the platform while at the same time developing their platform solution for new products, new customers, and new markets. This pivoting makes it possible to use the platform in a new context...

  10. Reef Habitat Type and Spatial Extent as Interacting Controls on Platform-Scale Carbonate Budgets

    Directory of Open Access Journals (Sweden)

    Chris T. Perry

    2017-06-01

    Full Text Available A coral reefs carbonate budget strongly influences reef structural complexity and net reef growth potential, and thus is increasingly recognized as a key “health” metric. Despite this, understanding of habitat specific budget states, how these scale across reef platforms, and our ability to quantify both framework and sediment production values remains limited. Here, we use in-situ census data from an atoll rim reef platform in the central Maldives to quantify rates of both reef framework and sediment production and loss within different platform habitats, and then combine these data with high-resolution habitat maps to quantify contributions to platform wide carbonate budgets. The net reef framework budget for the entire platform is extremely low (0.12 G, where G = Kg CaCO3 m−2 year−1, with a very high proportion (143,745 kg or 65.1% of total framework production generated within the platform margin reef zones, despite these comprising only ~8% of platform area. Net platform-scale sediment budgets are higher (1.04 G, but most is produced in the reef and platform margin hardground habitats, of which ~80% derives from parrotfish bioerosion. Significant quantities of new sediment (up to ~1 G derived from the calcareous green algae Halimeda are produced only in one habitat. All lagoonal habitats have negative or neutral net carbonate budgets. These data demonstrate the marked inter-habitat differences in reef carbonate budgets that occur across reef platforms, and the major dampening effect on overall platform scale budgets when rates are factored for habitat type and size. Furthermore, the data highlights the disproportionately important role that relatively small areas of reef habitat can have on the maintenance of net positive platform scale budgets. Because of the intrinsic link between carbonate production rates and reef-associated landform development and maintenance, these findings also have implications for understanding reef

  11. NASA Earth Exchange: A Collaborative Earth Science Platform

    Science.gov (United States)

    Nemani, R. R.; Votava, P.; Michaelis, A.; Melton, F. S.; Hashimoto, H.; Milesi, C.; Wang, W.; Ganguly, S.

    2010-12-01

    The NASA Earth Exchange (NEX) is a collaboration platform for the Earth science community creating new ways for scientific interaction and knowledge sharing. Funded through ARRA, NEX combines state-of-the-art supercomputing, Earth system modeling, workflow management, NASA remote sensing data feeds, and a social networking platform to deliver a complete work environment in which users can explore and analyze large datasets, run modeling codes, collaborate on new or existing projects, and quickly share results among the Earth science communities. The work environment provides NEX members with community supported modeling, analysis and visualization software in conjunction with datasets that are common to the Earth systems science domain. By providing data, software, and large-scale computing power together in a flexible framework, NEX reduces the need for duplicated efforts in downloading data, developing pre-processing software tools, and expanding local compute infrastructures—while accelerating fundamental research, development of new applications, and reducing project costs. The social networking platform provides a forum for NEX members to efficiently share datasets, results, algorithms, codes, and expertise with other members. Since all members' work environments reside on the collaborative platform, sharing may be done without the transfer of large volumes of data or the porting of complex codes—making NEX an ideal platform for building upon and exchanging research, and fostering innovation. Architecture of NEX integrating social networking, super-computing and data center. The prototyping facility allows users to test their models, algorithms prior to deploying them on the super-computers when required.

  12. Aneka Cloud Application Platform and Its Integration with Windows Azure

    CERN Document Server

    Wei, Yi; Vecchiola, Christian; Karunamoorthy, Dileban; Buyya, Rajkumar

    2011-01-01

    Aneka is an Application Platform-as-a-Service (Aneka PaaS) for Cloud Computing. It acts as a framework for building customized applications and deploying them on either public or private Clouds. One of the key features of Aneka is its support for provisioning resources on different public Cloud providers such as Amazon EC2, Windows Azure and GoGrid. In this chapter, we will present Aneka platform and its integration with one of the public Cloud infrastructures, Windows Azure, which enables the usage of Windows Azure Compute Service as a resource provider of Aneka PaaS. The integration of the two platforms will allow users to leverage the power of Windows Azure Platform for Aneka Cloud Computing, employing a large number of compute instances to run their applications in parallel. Furthermore, customers of the Windows Azure platform can benefit from the integration with Aneka PaaS by embracing the advanced features of Aneka in terms of multiple programming models, scheduling and management services, application...

  13. Disentangling Competition Among Platform Driven Strategic Groups

    DEFF Research Database (Denmark)

    Kazan, Erol; Tan, Chee-Wee; Lim, Eric

    2015-01-01

    In platform-driven markets, competitive advantage is derived from superior platform design and configurations. For this reason, platform owners strive to create unique and inimitable platform configurals to maintain and extend their competitiveness within network economies. To disentangle firm...... competition within platform-driven markets, we opted for the UK mobile payment market as our empirical setting. By embracing the theoretical lens of strategic groups and digital platforms, this study supplements prior research by deriving a taxonomy of platform-driven strategic groups that is grounded...... on competitive attributes of platform- driven markets; namely interfirm modularity and strategic linkages....

  14. Disentangling Competition Among Platform Driven Strategic Groups

    DEFF Research Database (Denmark)

    Kazan, Erol; Tan, Chee-Wee; Lim, Eric

    2015-01-01

    competition within platform-driven markets, we opted for the UK mobile payment market as our empirical setting. By embracing the theoretical lens of strategic groups and digital platforms, this study supplements prior research by deriving a taxonomy of platform-driven strategic groups that is grounded......In platform-driven markets, competitive advantage is derived from superior platform design and configurations. For this reason, platform owners strive to create unique and inimitable platform configurals to maintain and extend their competitiveness within network economies. To disentangle firm...... on competitive attributes of platform- driven markets; namely interfirm modularity and strategic linkages....

  15. Open Standards and Technologies in the S2S Framework

    Science.gov (United States)

    Maffei, A. R.; Rozell, E. A.; West, P.; Zednik, S.; Fox, P. A.

    2011-12-01

    The S2S Search Interface Framework provides tools and services to build customized user interfaces. It also serves as a focal point for repository managers to develop science data services and reusable components for search interfaces. The framework has been used to design a faceted browsing platform for web services, including OpenSearch and SAWSDL. This exemplar faceted browsing platform has been applied in our development of search interfaces for 1) an international open government dataset catalog and 2) a metadata catalog for biological and chemical oceanography. S2S was designed from the ground up using open standards and technologies. The framework was initially created to develop "data dashboard" interfaces on top of OpenSearch services, but has been generalized to support web services and standards with semantic annotation capabilities. We apply OWL, a W3C standard for ontologies on the Web, to create a vocabulary for the description of framework metadata. Our faceted browsing platform is heavily focused on the use of jQuery; we have created reusable user interface "widgets" that leverage OpenLayers and MapServer technology in geospatial selection and visualization, which can be used in this and future platforms. The use of open standards and technologies has enabled rapid iterations over software development lifecycles, and has kept the framework agile as new use cases and ideas have emerged.

  16. TRUSTED CLOUD COMPUTING FRAMEWORK FOR HEALTHCARE SECTOR

    Directory of Open Access Journals (Sweden)

    Mervat Adib Bamiah

    2014-01-01

    Full Text Available Cloud computing is rapidly evolving due to its efficient characteristics such as cost-effectiveness, availability and elasticity. Healthcare organizations and consumers lose control when they outsource their sensitive data and computing resources to a third party Cloud Service Provider (CSP, which may raise security and privacy concerns related to data loss and misuse appealing threats. Lack of consumers’ knowledge about their data storage location may lead to violating rules and regulations of Health Insurance Portability and Accountability Act (HIPAA that can cost them huge penalty. Fear of data breach by internal or external hackers may decrease consumers’ trust in adopting cloud computing and benefiting from its promising features. We designed a Healthcare Trusted Cloud Computing (HTCC framework that maintains security, privacy and considers HIPAA regulations. HTCC framework deploys Trusted Computing Group (TCG technologies such as Trusted Platform Module (TPM, Trusted Software Stack (TSS, virtual Trusted Platform Module (vTPM, Trusted Network Connect (TNC and Self Encrypting Drives (SEDs. We emphasize on using strong multi-factor authentication access control mechanisms and strict security controls, as well as encryption for data at storage, in-transit and while process. We contributed in customizing a cloud Service Level Agreement (SLA by considering healthcare requirements. HTCC was evaluated by comparing with previous researchers’ work and conducting survey from experts. Results were satisfactory and showed acceptance of the framework. We aim that our proposed framework will assist in optimizing trust on cloud computing to be adopted in healthcare sector.

  17. A Certification Framework for Cloud Security Properties: The Monitoring Path

    OpenAIRE

    2015-01-01

    In this paper we describe the structure and functionality of a certification integrated framework aimed to support the certification of security properties of a Cloud infrastructure (IaaS), a platform (PaaS), or the software layer (SaaS). Such framework will bring service users, service providers and cloud suppliers to work together with certification authorities in order to ensure security properties and certificates validity in the continuously evolving cloud environment. For this purpose, ...

  18. Evaluation of the Suitability of Alluxio for Hadoop Processing Frameworks

    CERN Document Server

    Lawrie, Christopher; CERN. Geneva. IT Department

    2016-01-01

    Alluxio is an open source memory speed virtual distributed storage platform. It sits between the storage and processing framework layers for big data processing and claims to heavily improve performance when data is required to be written/read at a high throughput; for example when a dataset is used by many jobs simultaneously. This report evaluates the viability of using Alluxio at CERN for Hadoop processing frameworks.

  19. A Component-based Software Development and Execution Framework for CAx Applications

    Directory of Open Access Journals (Sweden)

    N. Matsuki

    2004-01-01

    Full Text Available Digitalization of the manufacturing process and technologies is regarded as the key to increased competitive ability. The MZ-Platform infrastructure is a component-based software development framework, designed for supporting enterprises to enhance digitalized technologies using software tools and CAx components in a self-innovative way. In the paper we show the algorithm, system architecture, and a CAx application example on MZ-Platform. We also propose a new parametric data structure based on MZ-Platform.

  20. Programming Entity Framework

    CERN Document Server

    Lerman, Julia

    2010-01-01

    Get a thorough introduction to ADO.NET Entity Framework 4 -- Microsoft's core framework for modeling and interacting with data in .NET applications. The second edition of this acclaimed guide provides a hands-on tour of the framework latest version in Visual Studio 2010 and .NET Framework 4. Not only will you learn how to use EF4 in a variety of applications, you'll also gain a deep understanding of its architecture and APIs. Written by Julia Lerman, the leading independent authority on the framework, Programming Entity Framework covers it all -- from the Entity Data Model and Object Service

  1. Status report on SHARP coupling framework.

    Energy Technology Data Exchange (ETDEWEB)

    Caceres, A.; Tautges, T. J.; Lottes, J.; Fischer, P.; Rabiti, C.; Smith, M. A.; Siegel, A.; Yang, W. S.; Palmiotti, G.

    2008-05-30

    This report presents the software engineering effort under way at ANL towards a comprehensive integrated computational framework (SHARP) for high fidelity simulations of sodium cooled fast reactors. The primary objective of this framework is to provide accurate and flexible analysis tools to nuclear reactor designers by simulating multiphysics phenomena happening in complex reactor geometries. Ideally, the coupling among different physics modules (such as neutronics, thermal-hydraulics, and structural mechanics) needs to be tight to preserve the accuracy achieved in each module. However, fast reactor cores in steady state mode represent a special case where weak coupling between neutronics and thermal-hydraulics is usually adequate. Our framework design allows for both options. Another requirement for SHARP framework has been to implement various coupling algorithms that are parallel and scalable to large scale since nuclear reactor core simulations are among the most memory and computationally intensive, requiring the use of leadership-class petascale platforms. This report details our progress toward achieving these goals. Specifically, we demonstrate coupling independently developed parallel codes in a manner that does not compromise performance or portability, while minimizing the impact on individual developers. This year, our focus has been on developing a lightweight and loosely coupled framework targeted at UNIC (our neutronics code) and Nek (our thermal hydraulics code). However, the framework design is not limited to just using these two codes.

  2. Stratifying the Develoment of Product Platforms

    DEFF Research Database (Denmark)

    Sköld, Martin; Karlsson, Christer

    2013-01-01

    companies develop platforms for different aims, purposes, and product scopes. Following on from this, the requirements for platform development resources, the ways of organizing platform development, and the implications for management styles have not been explored and are presumably varying. To start...... influencing the project length, requirements for platform development resources, principles for organizing, and implications for management styles....

  3. New offshore platform in the Mexican Gulf

    Energy Technology Data Exchange (ETDEWEB)

    Beisel, T.

    1982-04-01

    After a construction period of only 10 months, the second steel Offshore platform was recently completed in the Mexican Gulf. The pattern for this structure was the Cognac platform. The erection of the new platform, called the 'Cerveza' platform, is described in the article.

  4. Centrifuge-Based Fluidic Platforms

    Science.gov (United States)

    Zoval, Jim; Jia, Guangyao; Kido, Horacio; Kim, Jitae; Kim, Nahui; Madou, Marc

    In this chapter centrifuge-based microfluidic platforms are reviewed and compared with other popular microfluidic propulsion methods. The underlying physical principles of centrifugal pumping in microfluidic systems are presented and the various centrifuge fluidic functions such as valving, decanting, calibration, mixing, metering, heating, sample splitting, and separation are introduced. Those fluidic functions have been combined with analytical measurements techniques such as optical imaging, absorbance and fluorescence spectroscopy and mass spectrometry to make the centrifugal platform a powerful solution for medical and clinical diagnostics and high-throughput screening (HTS) in drug discovery. Applications of a compact disc (CD)-based centrifuge platform analyzed in this review include: two-point calibration of an optode-based ion sensor, an automated immunoassay platform, multiple parallel screening assays and cellular-based assays. The use of modified commercial CD drives for high-resolution optical imaging is discussed as well. From a broader perspective, we compare the technical barriers involved in applying microfluidics for sensing and diagnostic as opposed to applying such techniques to HTS. The latter poses less challenges and explains why HTS products based on a CD fluidic platform are already commercially available, while we might have to wait longer to see commercial CD-based diagnostics.

  5. Platforms for Innovation and Internationalization

    Directory of Open Access Journals (Sweden)

    Erik Stavnsager Rasmussen

    2017-05-01

    Full Text Available The high-tech global startup has many challenges related to both innovation and internationalization. From a Danish cluster of Welfare Tech firms, eight innovative and international firms were selected and interviewed. Such firms typically have to be agile and operate in virtual networks in almost all parts of their value chains. This article contributes to the understanding of how innovation and internationalization to a great extent are interlinked. The firms have developed a core product or service offering, which the firms often describe as “a platform”. Around the platform, they develop their products and services for new customers and users in new countries. The firms have to sustain a strong focus on the platform while at the same time developing their platform solution for new products, new customers, and new markets. This pivoting makes it possible to use the platform in a new context but is highly demanding for the firms. They need to be extremely agile and fast-moving but at the same time still to have a focus on the core of the firm: the platform.

  6. The architecture for data, security and application in Digital Earth platform

    Science.gov (United States)

    Miao, Fang; Yang, Wenhui; Ye, Ansheng; Chen, Huayue

    2016-11-01

    Digital Earth platform is an application, service and decision support system, which integrates geo-spatial data acquisition, transmission, storage, processing, analysis, statistics and visualization. It realizes comprehensive management and widely application of different kinds of huge earth data under the geo-spatial framework and in a open environment. It should consider the continues growing of data and applications, as well as data security. According to the issues of how to safely use spatial data in Digital Earth platform, an architecture for data,security and application in Digital Earth platform was proposed in this paper. We call this architecture DOA(DOSA). In the digital earth platform on its goal is the Trusted Data. DOA(DOSA) and Trusted Data can provide data management, security grantee, application supporting for Digital Earth platform.

  7. On-field validation of the new platform for magnetic measurements at CERN

    CERN Document Server

    Arpaia, P; Inglese, V; Spiezia, G

    2009-01-01

    A new platform for magnetic measurements at the European Organization for Nuclear Research (CERN) is presented. The key concepts and the architecture of its main components, a multi-purpose digitizer (fast digital integrator – FDI) and a flexible software framework (flexible framework for magnetic measurements – FFMM), are detailed. The experimental results of the metrological characterization of FDI exhibit a significant advance with respect to the state of the art. Furthermore, the FFMM implementation is shown to provide a reusable and scalable measurement software. Finally, the results of the on-field validation of the platform for field measurements on superconducting magnets in the CERN test facility are discussed.

  8. Persistent Monitoring Platforms Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Bennett, C L

    2007-02-22

    This project was inspired and motivated by the need to provide better platforms for persistent surveillance. In the years since the inception of this work, the need for persistence of surveillance platforms has become even more widely appreciated, both within the defense community and the intelligence community. One of the most demanding technical requirements for such a platform involves the power plant and energy storage system, and this project concentrated almost exclusively on the technology associated with this system for a solar powered, high altitude, unmanned aircraft. An important realization for the feasibility of such solar powered aircraft, made at the outset of this project, was that thermal energy may be stored with higher specific energy density than for any other known practical form of rechargeable energy storage. This approach has proved to be extraordinarily fruitful, and a large number of spin-off applications of this technology were developed in the course of this project.

  9. Cerveza platforms offer economic options

    Energy Technology Data Exchange (ETDEWEB)

    Leblanc, L.A.

    1982-08-01

    Two single-piece platforms, Cerveze and Cerveza Ligera, were installed by Union Oil Co. in 925-935 ft of water. The technology and equipment used for the two platforms can be used for units to a depth of 1,400 ft in mild climates and to 1,000 ft in more critical weather areas such as the North Sea. The significant improvements in design and procedures in the construction and installation of the Cerveza Ligera platform are: (1) four leg structure, as opposed to eight, requiring less steel; (2) simplified fabrication; and (3) quicker installation. The most significant area of improvement in the Ligera project compared with Cerveza was in communications. Communications between naval architects and onshore launch foremen during loadout, and between surveyors and tug captains during positioning, are cited as examples.

  10. Deformations of crystal frameworks

    CERN Document Server

    Borcea, Ciprian S

    2011-01-01

    We apply our deformation theory of periodic bar-and-joint frameworks to tetrahedral crystal structures. The deformation space is investigated in detail for frameworks modelled on quartz, cristobalite and tridymite.

  11. Tax Responses in Platform Industries

    DEFF Research Database (Denmark)

    Kind, Hans Jarle; Köthenbürger, Marko; Schjelderup, Guttorm

    Two-sided platform firms serve distinct customer groups that are connected through interdependent demand, and include major businesses such as the media industry, banking, and the software industry. A well known result of tax incidence is that consumers of a more heavily taxed good pay a higher...... price and thus buy less of the good. The present paper shows that this result need not hold in a two-sided market. On the contrary, a higher ad valorem tax may lower end-user prices and spur sales. Thus, two-sided platform firms may not at all engage in tax shifting via price increases. We further show...

  12. Moodle vs. Social Media Platforms

    DEFF Research Database (Denmark)

    Gulieva, Valeria

    Given the competition coming from various social media platforms, it is explored in this paper how students could be encouraged to use Moodle more proactively during their studies. Moodle is a course management system for online learning. It is designed to be a flexible template-based system, which......, known and widely used social platforms. It might be also due to the fact that students do not see the benefits in investing time and efforts in learning the new system. Another reason might be the mandatory nature of Moodle, i.e., it is imposed on students, rather than a free choice – and this might...

  13. A practice scaffolding interactive platform

    DEFF Research Database (Denmark)

    Bundsgaard, Jeppe

    2009-01-01

    , structures the students' activity, and interactively supports subject learning. A PracSIP facilitates students' development of complex competencies, and at the same time it supports the students' development of skills defined in the curriculum. The paper introduces the concept, presents the theoretical......A Practice Scaffolding Interactive Platform (PracSIP) is a social learning platform which supports students in collaborative project based learning by simulating a professional practice. A PracSIP puts the core tools of the simulated practice at the students' disposal, it organizes collaboration...

  14. OJADEAC: An Ontology Based Access Control Model for JADE Platform

    Directory of Open Access Journals (Sweden)

    Ban Sharief Mustafa

    2014-06-01

    Full Text Available Java Agent Development Framework (JADE is a software framework to make easy the development of Multi-Agent applications in compliance with the Foundation for Intelligent Physical Agents (FIPA specifications. JADE propose new infrastructure solutions to support the development of useful and convenient distributed applications. Security is one of the most important issues in implementing and deploying such applications. JADE-S security add-ons are one of the most popular security solutions in JADE platform. It provides several security services including authentication, authorization, signature and encryption services. Authorization service will give authorities to perform an action based on a set of permission objects attached to every authenticated user. This service has several drawbacks when implemented in a scalable distributed context aware applications. In this paper, an ontology-based access control model called (OJADEAC is proposed to be applied in JADE platform by combining Semantic Web technologies with context-aware policy mechanism to overcome the shortcoming of this service. The access control model is represented by a semantic ontology, and a set of two level semantic rules representing platform and application specific policy rules. OJADEAC model is distributed, intelligent, dynamic, context-aware and use reasoning engine to infer access decisions based on ontology knowledge.

  15. A Hardware Framework for on-Chip FPGA Acceleration

    DEFF Research Database (Denmark)

    Lomuscio, Andrea; Cardarilli, Gian Carlo; Nannarelli, Alberto

    2016-01-01

    In this work, we present a new framework to dynamically load hardware accelerators on reconfigurable platforms (FPGAs). Provided a library of application-specific processors, we load on-the-fly the specific processor in the FPGA, and we transfer the execution from the CPU to the FPGA-based accele...

  16. A Hardware Framework for on-Chip FPGA Acceleration

    DEFF Research Database (Denmark)

    Lomuscio, Andrea; Cardarilli, Gian Carlo; Nannarelli, Alberto

    2016-01-01

    In this work, we present a new framework to dynamically load hardware accelerators on reconfigurable platforms (FPGAs). Provided a library of application-specific processors, we load on-the-fly the specific processor in the FPGA, and we transfer the execution from the CPU to the FPGA...

  17. Framework for Naval Cooperation between Vietnam and the United States

    Science.gov (United States)

    2017-06-09

    the Vietnam-United States relationship has taken giant steps forward in virtually every aspect, especially solidified by a Comprehensive Partnership... platform for future relationship between Vietnam and the United States. Finally, this research suggests a framework for naval cooperation between Vietnam...United States relationship has taken giant steps forward in virtually every aspect, especially solidified by a Comprehensive Partnership Agreement signed

  18. The IPBES Conceptual Framework - connecting nature and people

    DEFF Research Database (Denmark)

    Díaz, Sandra; Demissew, Sebsebe; Carabias, Julia;

    2015-01-01

    The first public product of the Intergovernmental Platform on Biodiversity and Ecosystem Services (IPBES) is its Conceptual Framework. This conceptual and analytical tool, presented here in detail, will underpin all IPBES functions and provide structure and comparability to the syntheses that IPB...

  19. Programming Entity Framework

    CERN Document Server

    Lerman, Julia

    2009-01-01

    Programming Entity Framework is a thorough introduction to Microsoft's new core framework for modeling and interacting with data in .NET applications. This highly-acclaimed book not only gives experienced developers a hands-on tour of the Entity Framework and explains its use in a variety of applications, it also provides a deep understanding of its architecture and APIs -- knowledge that will be extremely valuable as you shift to the Entity Framework version in .NET Framework 4.0 and Visual Studio 2010. From the Entity Data Model (EDM) and Object Services to EntityClient and the Metadata Work

  20. An XML Driven Framework for Test Control and Data Analysis

    CERN Document Server

    Nogiec, J M; Walbridge, D G C; Desavouret, E

    2001-01-01

    An extensible, component-based framework has been developed at Fermilab to promote software reuse and provide a common platform for developing a family of test and data analysis systems. The framework allows for configuring applications from components through the use of XML configurations. It can be easily extended by adding new components and many application independent components are already provided with the framework. The core of the system has been developed in Java which guarantees its portability and facilitates the use of object-oriented development technologies.

  1. The Common Data Acquisition Platform in the Helmholtz Association

    Science.gov (United States)

    Kaever, P.; Balzer, M.; Kopmann, A.; Zimmer, M.; Rongen, H.

    2017-04-01

    Various centres of the German Helmholtz Association (HGF) started in 2012 to develop a modular data acquisition (DAQ) platform, covering the entire range from detector readout to data transfer into parallel computing environments. This platform integrates generic hardware components like the multi-purpose HGF-Advanced Mezzanine Card or a smart scientific camera framework, adding user value with Linux drivers and board support packages. Technically the scope comprises the DAQ-chain from FPGA-modules to computing servers, notably frontend-electronics-interfaces, microcontrollers and GPUs with their software plus high-performance data transmission links. The core idea is a generic and component-based approach, enabling the implementation of specific experiment requirements with low effort. This so called DTS-platform will support standards like MTCA.4 in hard- and software to ensure compatibility with commercial components. Its capability to deploy on other crate standards or FPGA-boards with PCI express or Ethernet interfaces remains an essential feature. Competences of the participating centres are coordinated in order to provide a solid technological basis for both research topics in the Helmholtz Programme ``Matter and Technology'': ``Detector Technology and Systems'' and ``Accelerator Research and Development''. The DTS-platform aims at reducing costs and development time and will ensure access to latest technologies for the collaboration. Due to its flexible approach, it has the potential to be applied in other scientific programs.

  2. 2009 Analysis Platform Review Report

    Energy Technology Data Exchange (ETDEWEB)

    Ferrell, John [Office of Energy Efficiency and Renewable Energy (EERE), Washington, DC (United States

    2009-12-01

    This document summarizes the recommendations and evaluations provided by an independent external panel of experts at the U.S. Department of Energy Biomass Program’s Analysis platform review meeting, held on February 18, 2009, at the Marriott Residence Inn, National Harbor, Maryland.

  3. 2009 Infrastructure Platform Review Report

    Energy Technology Data Exchange (ETDEWEB)

    Ferrell, John [Office of Energy Efficiency and Renewable Energy (EERE), Washington, DC (United States)

    2009-12-01

    This document summarizes the recommendations and evaluations provided by an independent external panel of experts at the U.S. Department of Energy Biomass program‘s Infrastructure platform review meeting, held on February 19, 2009, at the Marriott Residence Inn, National Harbor, Maryland.

  4. Venus Atmospheric Maneuverable Platform (VAMP)

    Science.gov (United States)

    Polidan, R.; Lee, G.; Sokol, D.; Griffin, K.; Bolisay, L.

    2014-05-01

    VAMP is a long lived, semi-buoyant, atmospheric “rover” that deploys in orbit, enters the Venus atmosphere and flies in the Venus atmosphere between 55 and 70 km for up to one year as a platform to address VEXAG goals I.A, I.B, and I.C.

  5. Utilizing platforms in industrialized construction

    DEFF Research Database (Denmark)

    Bonev, Martin; Wörösch, Michael; Hvam, Lars

    2015-01-01

    Purpose – The purpose of this paper is to explore the development of a platform-based projectexecution in the industrialised construction sector, with a focus on systematically balancing cost andvalue. Offering custom-tailored buildings at reasonable costs has been a growing concern for manyconst...

  6. Generational Transitions in Platform Markets

    DEFF Research Database (Denmark)

    Kretschmer, Tobias; Claussen, Jörg

    2016-01-01

    The introduction of a new product generation forces incumbents in platform markets to rebuild their installed base of complementary products. Using three different data sets on the U.S. market for video game consoles, we show that incumbents can, to some extent, substitute for rebuilding their new...

  7. Analysis of offshore jacket platform

    Digital Repository Service at National Institute of Oceanography (India)

    Harish, N.; Mandal, S.; Shanthala, B.; Rao, S.

    -Rohman, M., ‘Multi-loop feedback control of offshore steel jacket platforms’, Computers & Structures 70, 1999, 185–202. 11.Yamamoto, I., Terada, Y., and Yokokura, K., ‘An application of a position keeping control system to floating offshore platform...

  8. Tax Responses in Platform Industries

    DEFF Research Database (Denmark)

    Kind, Hans Jarle; Köthenbürger, Marko; Schjelderup, Guttorm

    Two-sided platform firms serve distinct customer groups that are connected through interdependent demand, and include major businesses such as the media industry, banking, and the software industry. A well known result of tax incidence is that consumers of a more heavily taxed good pay a higher...

  9. 2009 Feedstocks Platform Review Report

    Energy Technology Data Exchange (ETDEWEB)

    Ferrell, John [Office of Energy Efficiency and Renewable Energy (EERE), Washington, DC (United States)

    2009-12-01

    This document summarizes the recommendations and evaluations provided by an independent external panel of experts at the U.S. Department of Energy Biomass Program‘s Feedstock platform review meeting, held on April 8–10, 2009, at the Grand Hyatt Washington, Washington, D.C.

  10. An archetype-based testing framework.

    Science.gov (United States)

    Chen, Rong; Garde, Sebastian; Beale, Thomas; Nyström, Mikael; Karlsson, Daniel; Klein, Gunnar O; Ahlfeldt, Hans

    2008-01-01

    With the introduction of EHR two-level modelling and archetype methodologies pioneered by openEHR and standardized by CEN/ISO, we are one step closer to semantic interoperability and future-proof adaptive healthcare information systems. Along with the opportunities, there are also challenges. Archetypes provide the full semantics of EHR data explicitly to surrounding systems in a platform-independent way, yet it is up to the receiving system to interpret the semantics and process the data accordingly. In this paper we propose a design of an archetype-based platform-independent testing framework for validating implementations of the openEHR archetype formalism as a means of improving quality and interoperability of EHRs.

  11. Home Infotainment Platform - A Ubiquitous Access Device for Masses

    Science.gov (United States)

    Pal, Arpan; Prashant, M.; Ghose, Avik; Bhaumik, Chirabrata

    There is tremendous need for a low-cost Internet-Enabled Platform for developing countries like India that uses TV as the display medium and can connect to Internet using various available connectivity solutions. The paper presents how a generic framework middleware can be used to create a Home Infotainment Platform that can support variety of value-added applications. It also talks about the innovative designs employed to bring about the low-cost solution keeping in mind both the limitations of TV as a display and non-availability of high quality-of-service networks. Finally the social, economic and environmental implications of wide-spread deployment of the proposed solution are outlined.

  12. Current State and Development Trends for Integration Platforms

    Institute of Scientific and Technical Information of China (English)

    1999-01-01

    The integration platform (IP) is an advanced support tool for application softwa re development and integration. This paper analyzes the shortcomings of traditio nal software programming methods, introduces the background and development of i ntegration platforms and presents the basic functions and system architecture of computer integrated manufacture computing environment (CCE) IP as well as the i ntegration framework. Computer integrated manufacturing system (CIMS) applicatio n IP is defined i n relation to the IP requirements for CIMS implementation within a company. The CIMS application IP is not only a support tool for application software developm ent, but also a support tool for software integration and system operation. Ther efore, the behavior and functions of a CIMS application IP must also include sof tware integration and system operation. The development trend for CIMS applicati on IPs is discussed in view of software technology development trends.

  13. Climate Users Interface Platform: some preliminary ideas from EUPORIAS experience

    Science.gov (United States)

    Buontempo, Carlo; Dell'Aquila, Alessandro

    2016-04-01

    One of the most important and yet least developed component of the GFCS is probably the Climate Users Interface Platform (CUIP). At front of its centrality in the framework, the development of this component has suffered from the existence of a series of pre-conceived ideas of what a users interface should look like. The FP7 project EUPORIAS promised in its description of work to develop and deliver an online users interface platform. This paper summarises the process EUPORIAS has been through to define and deliver the CUIP. The paper also highlighted what are the characteristics that a CUIP must have to ensure its ability to engage the users. Finally the paper identifies a number of errors that are often committed when thinking about user interface and try to identifies a set of key principles that should be considered when developing the CUIP.

  14. A failed platform: The Citizen Consensus Conference travels to Chile.

    Science.gov (United States)

    Ureta, Sebastián

    2016-05-01

    This article starts by reviewing the setbacks that the recent Science and Technology Studies literature has identified in the functioning of technologies of democracy, the different arrangements that look to enact deliberation on technoscientific issues. Putting a focus on the Citizen Consensus Conference, it then proposes that several of these setbacks are related to the kind of "work" that these technologies are expected to do, identifying two kinds of it: performing a laboratory-based experiment and constituting a platform for the dissemination of facts. It then applies this framework to study a Citizen Consensus Conference carried out in Chile in 2003. After a detailed genealogy of the planning, implementation and afterlife of this exercise, the article concludes that several of the limitations experienced are derived from a "successful outcome" conceived as solely running a neat lab-based experiment, arguing for the need to incorporate its functioning as a platform with all the associated transformations and messiness.

  15. Purification and Initial Studies of the Water-Soluble Polysaccharide RCP From the Roots of Rubus crataegiflolius Bge%托盘根水溶性多糖的分离纯化及初步研究

    Institute of Scientific and Technical Information of China (English)

    张旭; 房金波; 梁忠岩

    2005-01-01

    托盘根经热水煮提、醇析、脱淀粉、冻融离心、蛋白酶解、Sevagc法脱蛋白、超滤、凝胶柱层析方法纯化得水溶性多糖RCP,经比旋光度测定、高效液相色谱(HPLC)分析证明RCP为均一组分,分子量7000左右;气相色谱(GC)分析其单糖组成主要为葡萄糖和迹量的鼠李糖.说明RCP是一种中性杂多糖.

  16. The Analysis of the RCP Financing Mode in West Water Conservancy Construction Project%西部公益型水利建设项目应用RCP融资模式的探析

    Institute of Scientific and Technical Information of China (English)

    郭峰; 舒灵智; 廖博

    2009-01-01

    为了解决西部地区公益型水利建设项目融资困难的问题,引入RCP(资源-补偿-项目)融资模式,分析了我国现行水利项目融资基本模式和存在问题,对RCP融资模式进行了概述,并运用SWOT分析法论证了西部公益性水利建设项目中应用RCP融资模式的可行性.这种融资模式能够吸引更多民间资本参与水利项目的建设.提高社会资金的使用效率,为解决水利建设中的融资难题提供了途径和可能.

  17. RCP01: a Monte Carlo program for solving neutron and photon transport problems in three-dimensional geometry with detailed energy description (LWBR development program). [For CDC-6600 and -7600, in FORTRAN

    Energy Technology Data Exchange (ETDEWEB)

    Candelore, N R; Gast, R C; Ondis, II, L A

    1978-08-01

    The RCP01 Monte Carlo program for the CDC-7600 and CDC-6600 performs fixed source or eigenfunction neutron reaction rate calculations, or photon reaction rate calculations, for complex geometries. The photon calculations may be linked to the neutron reaction rate calculations. For neutron calculations, the full energy range is treated as required for neutron birth by the fission process and the subsequent neutron slowing down and thermalization, i.e., 10 MeV to 0 eV; for photon calculations the same energy range is treated. The detailed cross sections required for the neutron or photon collision processes are provided by RCPL1. This report provides details of the various types of neutron and photon starts and collisions, the common geometry tracking, and the input required. 37 figures, 1 table.

  18. Biofacies evolution in the Triassic platforms of the Dolomites, Italy

    Directory of Open Access Journals (Sweden)

    Franco Russo

    2005-10-01

    Full Text Available The Triassic of the Dolomites includes many carbonate platform generations, ranging in age from the Anisian to the Norian-Rhaetian. After the Permian-Triassic biological crisis, “reef” communities reappeared during the Anisian time. These buildups were generally characterized by a limited relief, lacking any primary skeletal framework and evidence of syndepositional cementation. The microfacies are dominated by micrites, mainly allochthonous or detrital in origin. The sparse biota are generally binder and buffler organisms, such as dasycladacean algae, sphinctozoans and briozoans.The second generation of carbonate buildups (late Anisian–early Ladinian, Sciliar Fm are dominated by syndepositional cements (e.g. Marmolada Platform. These cements represent the main component of margin and upper slope facies. They form more or less isolated or laterally linked bodies: the “evinosponges”. During the late Ladinian and Carnian p.p., the post-volcanic platforms developed (Cassian Dolomite. The microfacies of these platforms manly consist of micrites, cements and skeletons. The automicrites constitute more than 50% of the rock volume, the cements the 20%, and the skeletal organisms less than the 10%. The metazoan contribution is subordinated to that of skeletal cyanobacteria, like Cladogirvanella cipitensis and microproblematica, like Tubyphites. The primary marine cements provide evidence of a widespread early syndepositional lithification. Towards the top of Julian Substage (Carnian, at the base of the Heiligkreutz/Dürrenstein Formation (i.e. Alpe di Specie, small calcareous bioconstructions, interpreted as patch-reefs, show a much more “modern” faunal association. For the first time in the Triassic, a primary skeletal framework developed, largely formed by calcified demosponges and scleractinians. Corals were still subordinated to sponges. Taxonomic diversity increases greatly and the skeletal component exceeds the 50% of the rock volume

  19. Identification and characterization of intermediates in the formation of the cyclobutadiene linked dimeric cobalt sandwich compound [(5-RCp)Co(4-C4Ph3)]2 [R = H, CH3C(O)O

    Indian Academy of Sciences (India)

    Nem Singh; Anil J Elias

    2011-11-01

    The synthesis of novel cyclobutadiene linked dimers of [5-RCp]Co(4-C4Ph4) was reported recently from a three-component reaction of 1,4-diphenylbutadiyne, diphenylacetylene and [5-RCp]Co(PPh3)2 [R = H or MeOC(O)]. The chiral bis oxazoline derivative of this dimer was found to form cobalt oxazolinyl palladacycles which were excellent chiral catalysts for the Overman-Claisen rearrangement of trichloroacetimidates, similar to the well-known COP catalysts. In this paper, we report reactions carried out for identifying the intermediates in the formation of the dimeric sandwich compound {[5-MeOC(O)Cp]Co(4-C4Ph3)}2 (1). On varying the stoichiometric ratio of the reactants of the three component reaction, two new cobalt sandwich compounds [5-MeOC(O)Cp]Co[4-C4Ph3(C≡CPh)] (2) and [5-MeOC(O)Cp]Co[4-C4-Ph2(C≡CPh)2] (3) were found to form as viscous oily liquids. The identity of 2 was ascertained by oxidizing its alkyne moiety to yield crystalline [5-MeOC(O)Cp]Co{4-C4Ph3[C(O)-C(O)Ph]} (4) which was structurally characterized. Further, the role of phenylethynyl derived monomeric sandwich compound 2 as a precursor to the dimeric compound 1 was established by reacting 2 with diphenylacetylene and CpCo(COD) which yielded the first example of an unsymmetrical cyclobutadiene linked dimeric cobalt sandwich compound {5-[MeOC(O)Cp]Co(4-C4Ph3)}[(5-Cp)Co(4-C4Ph3)] (5) which was also structurally characterized.

  20. UrbanWeb: a Platform for Mobile Context-aware Social Computing

    DEFF Research Database (Denmark)

    Hansen, Frank Allan; Grønbæk, Kaj

    2010-01-01

    UrbanWeb is a novel Web-based context-aware hypermedia plat- form. It provides essential mechanisms for mobile social comput- ing applications: the framework implements context as an exten- sion to Web 2.0 tagging and provides developers with an easy to use platform for mobile context-aware appli...

  1. Secure public cloud platform for medical images sharing.

    Science.gov (United States)

    Pan, Wei; Coatrieux, Gouenou; Bouslimi, Dalel; Prigent, Nicolas

    2015-01-01

    Cloud computing promises medical imaging services offering large storage and computing capabilities for limited costs. In this data outsourcing framework, one of the greatest issues to deal with is data security. To do so, we propose to secure a public cloud platform devoted to medical image sharing by defining and deploying a security policy so as to control various security mechanisms. This policy stands on a risk assessment we conducted so as to identify security objectives with a special interest for digital content protection. These objectives are addressed by means of different security mechanisms like access and usage control policy, partial-encryption and watermarking.

  2. Product Platform Development in Industrial Networks

    DEFF Research Database (Denmark)

    Karlsson, Christer; Skold, Martin

    2011-01-01

    The article examines the strategic issues involved in the deployment of product platform development in an industrial network. The move entails identifying the types and characteristics of generically different product platform strategies and clarifying strategic motives and differences. Number...

  3. Parametric modelling of nonstationary platform deck motions

    Digital Repository Service at National Institute of Oceanography (India)

    Mandal, S.

    -sense-stationary processes. Then the time series are modelled by the maximum entropy method which is formulated here for spectral estimation of platform deck displacements. The lower order maximum entropy spectra of nonstationary platform deck displacements are compared...

  4. Front-end conceptual platform modeling

    DEFF Research Database (Denmark)

    Guðlaugsson, Tómas Vignir; Ravn, Poul Martin; Mortensen, Niels Henrik

    2014-01-01

    Platform thinking has been the subject of investigation and deployment in many projects in both academia and industry. Most contributions involve the restructuring of product programs, and only a few support front-end development of a new platform in parallel with technology development....... This contribution deals with the development of product platforms in front-end projects and introduces a modeling tool: the Conceptual Product Platform model. State of the art within platform modeling forms the base of a modeling formalism for a Conceptual Product Platform model. The modeling formalism is explored...... through an example and applied in a case in which the Conceptual Product Platform model has supported the front-end development of a platform for an electro-active polymer technology. The case describes the contents of the model and how its application supported the development work in the project...

  5. The Logic of Digital Platform Disruption

    DEFF Research Database (Denmark)

    Kazan, Erol; Tan, Chee-Wee; Lim, Eric T. K.

    Digital platforms are disruptive IT artifacts, because they facilitate the quick release of innovative platform derivatives from third parties (e.g., apps). This study endeavours to unravel the disruptive potential, caused by distinct designs and configurations of digital platforms on market...... environments. We postulate that the disruptive potential of digital platforms is determined by the degree of alignment among the business, technology and platform profiles. Furthermore, we argue that the design and configuration of the aforementioned three elements dictates the extent to which open innovation...... is permitted. To shed light on the disruptive potential of digital platforms, we opted for payment platforms as our unit of analysis. Through interviews with experts and payment providers, we seek to gain an in-depth appreciation of how contemporary digital payment platforms are designed and configured...

  6. Modeling and analysis of offshore jacket platform

    Digital Repository Service at National Institute of Oceanography (India)

    Mohan, P.; Sidhaarth, K.R.A.; SanilKumar, V.

    This paper details the results obtained from static analysis, considering both operational and ultimate limit state performance characteristics of a jacket platform, designed at Mumbai high basin. The existing platforms at Mumbai high region...

  7. The Logic of Digital Platform Disruption

    DEFF Research Database (Denmark)

    Kazan, Erol; Tan, Chee-Wee; Lim, Eric T. K.

    Digital platforms are disruptive IT artifacts, because they facilitate the quick release of innovative platform derivatives from third parties (e.g., apps). This study endeavours to unravel the disruptive potential, caused by distinct designs and configurations of digital platforms on market...... environments. We postulate that the disruptive potential of digital platforms is determined by the degree of alignment among the business, technology and platform profiles. Furthermore, we argue that the design and configuration of the aforementioned three elements dictates the extent to which open innovation...... is permitted. To shed light on the disruptive potential of digital platforms, we opted for payment platforms as our unit of analysis. Through interviews with experts and payment providers, we seek to gain an in-depth appreciation of how contemporary digital payment platforms are designed and configured...

  8. Product Platform Development in Industrial Networks

    DEFF Research Database (Denmark)

    Karlsson, Christer; Skold, Martin

    2011-01-01

    The article examines the strategic issues involved in the deployment of product platform development in an industrial network. The move entails identifying the types and characteristics of generically different product platform strategies and clarifying strategic motives and differences. Number...

  9. Software development on the SAP HANA platform

    CERN Document Server

    Walker, Mark

    2013-01-01

    Software Development on the SAP HANA Platform is a general tutorial guide to SAP HANA.This book is written for beginners to the SAP HANA platform. No knowledge of SAP HANA is necessary to start using this book.

  10. Hierarchical DSE for multi-ASIP platforms

    DEFF Research Database (Denmark)

    Micconi, Laura; Corvino, Rosilde; Gangadharan, Deepak;

    2013-01-01

    This work proposes a hierarchical Design Space Exploration (DSE) for the design of multi-processor platforms targeted to specific applications with strict timing and area constraints. In particular, it considers platforms integrating multiple Application Specific Instruction Set Processors (ASIPs...

  11. A Platform for Spreadsheet Composition

    CERN Document Server

    Baglietto, Pierpaolo; Mangiante, Simone; Maresca, Massimo; Parodi, Andrea; Stecca, Michele

    2011-01-01

    A huge amount of data is everyday managed in large organizations in many critical business sectors with the support of spreadsheet applications. The process of elaborating spreadsheet data is often performed in a distributed, collaborative way, where many actors enter data belonging to their local business domain to contribute to a global business view. The manual fusion of such data may lead to errors in copy-paste operations, loss of alignment and coherency due to multiple spreadsheet copies in circulation, as well as loss of data due to broken cross-spreadsheet links. In this paper we describe a methodology, based on a Spreadsheet Composition Platform, which greatly reduces these risks. The proposed platform seamlessly integrates the distributed spreadsheet elaboration, supports the commonly known spreadsheet tools for data processing and helps organizations to adopt a more controlled and secure environment for data fusion.

  12. Platform-Independent Courseware Sharing

    Directory of Open Access Journals (Sweden)

    Takao Shimomura

    2013-04-01

    Full Text Available Courseware distribution between different platforms is the major issue of current e-Learning. SCORM (Sharable Content Object Reference Model is one of the solutions for courseware sharing. However, to make SCORM-conformable courseware, some knowledge about HTML and JavaScript is required. This paper presents a SWF (Sharable Web Fragment-based e-Learning system, where courseware is created with sharable Web fragments such as Web pages, images and other resources, and the courseware can be distributed to another platform by export and import facilities. It also demonstrates how to export a subject that contains assignments and problems and how to import the whole subject, only the assignments, or only the problems. The exported meta-information is architecture-independent and provides a model of courseware distribution.

  13. Stabilisation problem in biaxial platform

    Directory of Open Access Journals (Sweden)

    Lindner Tymoteusz

    2016-12-01

    Full Text Available The article describes investigation of rolling ball stabilization problem on a biaxial platform. The aim of the control system proposed here is to stabilize ball moving on a plane in equilibrium point. The authors proposed a control algorithm based on cascade PID and they compared it with another control method. The article shows the results of the accuracy of ball stabilization and influence of applied filter on the signal waveform. The application used to detect the ball position measured by digital camera has been written using a cross platform .Net wrapper to the OpenCV image processing library - EmguCV. The authors used the bipolar stepper motor with dedicated electronic controller. The data between the computer and the designed controller are sent with use of the RS232 standard. The control stand is based on ATmega series microcontroller.

  14. DATABASE REPLICATION IN HETEROGENOUS PLATFORM

    Directory of Open Access Journals (Sweden)

    Hendro Nindito

    2014-01-01

    Full Text Available The application of diverse database technologies in enterprises today is increasingly a common practice. To provide high availability and survavibality of real-time information, a database replication technology that has capability to replicate databases under heterogenous platforms is required. The purpose of this research is to find the technology with such capability. In this research, the data source is stored in MSSQL database server running on Windows. The data will be replicated to MySQL running on Linux as the destination. The method applied in this research is prototyping in which the processes of development and testing can be done interactively and repeatedly. The key result of this research is that the replication technology applied, which is called Oracle GoldenGate, can successfully manage to do its task in replicating data in real-time and heterogeneous platforms.

  15. YARP: Yet Another Robot Platform

    Directory of Open Access Journals (Sweden)

    Lorenzo Natale

    2008-11-01

    Full Text Available We describe YARP, Yet Another Robot Platform, an open-source project that encapsulates lessons from our experience in building humanoid robots. The goal of YARP is to minimize the effort devoted to infrastructure-level software development by facilitating code reuse, modularity and so maximize research-level development and collaboration. Humanoid robotics is a "bleeding edge" field of research, with constant flux in sensors, actuators, and processors. Code reuse and maintenance is therefore a significant challenge. We describe the main problems we faced and the solutions we adopted. In short, the main features of YARP include support for inter-process communication, image processing as well as a class hierarchy to ease code reuse across different hardware platforms. YARP is currently used and tested on Windows, Linux and QNX6 which are common operating systems used in robotics.

  16. Multithreading platform for multimedia applications

    Science.gov (United States)

    Koster, Rainer; Kramp, Thorsten

    2000-12-01

    Complex multimedia applications have diverse resource and timing requirements. A platform for building such programs therefore should supply the developer with mechanisms for managing concurrency, communication, and real-time constraints but should remain flexible with regard to scheduling policies and interaction models. We have developed such a platform consisting of a user-level threads package and operating system extensions. The threads package offers a message-based threading model uniformly integrating synchronous and asynchronous communication, inter-thread synchronization, and signal handling as well as real-time functionality and application-specific scheduling. To support this user-space flexibility an upcall mechanism links the user-level scheduler to the kernel.

  17. Stabilisation problem in biaxial platform

    Science.gov (United States)

    Lindner, Tymoteusz; Rybarczyk, Dominik; Wyrwał, Daniel

    2016-12-01

    The article describes investigation of rolling ball stabilization problem on a biaxial platform. The aim of the control system proposed here is to stabilize ball moving on a plane in equilibrium point. The authors proposed a control algorithm based on cascade PID and they compared it with another control method. The article shows the results of the accuracy of ball stabilization and influence of applied filter on the signal waveform. The application used to detect the ball position measured by digital camera has been written using a cross platform .Net wrapper to the OpenCV image processing library - EmguCV. The authors used the bipolar stepper motor with dedicated electronic controller. The data between the computer and the designed controller are sent with use of the RS232 standard. The control stand is based on ATmega series microcontroller.

  18. Climate News Across Media Platforms

    DEFF Research Database (Denmark)

    Eskjær, Mikkel Fugl

    2015-01-01

    In a changing media landscape marked by technological, institutional and cultural convergence, comparative and cross-media content analysis represents a valuable analytical tool in mapping the diverse channels of climate change communication. This paper presents a comparative study of climate...... change news on five different media platforms: newspapers, television, radio, web-news and mobile news. It investigates the themes and actors represented in public climate change communication as well as the diverse possibilities of participating in public debates and information sharing. By combining...... quantitative and qualitative content analysis the paper documents and explores the extent and character of climate change news across different media platforms. The study aims at contributing to the on-going assessment of how news media are addressing climate change at a time when old and new media...

  19. Secure eHealth-Care Service on Self-Organizing Software Platform

    Directory of Open Access Journals (Sweden)

    Im Y. Jung

    2014-01-01

    Full Text Available There are several applications connected to IT health devices on the self-organizing software platform (SoSp that allow patients or elderly users to be cared for remotely by their family doctors under normal circumstances or during emergencies. An evaluation of the SoSp applied through PAAR watch/self-organizing software platform router was conducted targeting a simple user interface for aging users, without the existence of extrasettings based on patient movement. On the other hand, like normal medical records, the access to, and transmission of, health information via PAAR watch/self-organizing software platform requires privacy protection. This paper proposes a security framework for health information management of the SoSp. The proposed framework was designed to ensure easy detection of identification information for typical users. In addition, it provides powerful protection of the user’s health information.

  20. Modular Platforms for Optofluidic Systems

    Science.gov (United States)

    Brammer, Marko; Mappes, Timo

    2014-01-01

    Optofluidics is increasingly gaining impact in a number of different fields of research, namely biology and medicine, environmental monitoring and green energy. However, the market for optofluidic products is still in the early development phase. In this manuscript, we discuss modular platforms as a potential concept to facilitate the transfer of optofluidic sensing systems to an industrial implementation. We present microfluidic and optical networks as a basis for the interconnection of optofluidic sensor modules. Finally, we show the potential for entire optofluidic networks

  1. Frameworks in CS1

    DEFF Research Database (Denmark)

    Christensen, Henrik Bærbak; Caspersen, Michael Edelgaard

    2002-01-01

    point for introducing graphical user interface frameworks such as Java Swing and AWT as the students are not overwhelmed by all the details of such frameworks right away but given a conceptual road-map and practical experience that allow them to cope with the complexity.......In this paper we argue that introducing object-oriented frameworks as subject already in the CS1 curriculum is important if we are to train the programmers of tomorrow to become just as much software reusers as software producers. We present a simple, graphical, framework that we have successfully...

  2. Electrorheological fluid-actuated flexible platform

    Science.gov (United States)

    Liu, Liyu; Niu, Xize; Wen, Weijia; Sheng, Ping

    2006-04-01

    The design, fabrication, and performance of an electrorheological (ER) fluid-actuated flexible platform integrated on a microfluidic chip are reported in this letter. The digitally regulated ER microvalves control the four diaphragms on which a platform is sustained. With electrical input signals, the platform can perform vibrations at tunable frequencies as well as generate complex leveling modes. The flexible platform can potentially act as a microdamper when its inputs are generated from a sensor, in combination with a feedback control system.

  3. A study of simulation and prediction of extratropical cyclones over the Northern Hemisphere partⅡ:Future changes under RCP4.5 projected by the 6 CMIP5 coupled models%北半球温带气旋的模拟和预估研究Ⅱ∶6个 CMIP5耦合模式预估的未来 RCP4.5情景下的变化

    Institute of Scientific and Technical Information of China (English)

    张颖娴; 丁一汇

    2014-01-01

    The simulation results of the 6 climate coupled models of CMIP5 under the secondary emission scenarion RCP4.5 (Representative Concentration Pathway 4.5)are used to estimate the changes of the extratropical cyclone (EC)numbers and EC intensity,as well as the storm track and its strength in the future.The results indicate that:(1)although each model dif¯ fers in the simulations of the regional cyclogenesis during 2053—2100 under RCP4.5 relative to the second half of the 20th cen¯ tury,it is similarly found that ECs would decrease integrally in the Northern Hemisphere,especially in the lower latitudes.(2) The central pressure of ECs over the Northern Hemisphere would depress and the vorticity intensity would weaken in the future reproduced by models consistently.The simulated Atlantic storm track would move polewards sequentially but with weakened strength as are shown by most of the models in the future;the simulated Pacific storm track would also migrate polewards by more than half the models,but with intensity changes differing in the different seasons.And,(3)a poleward movement of the future baroclinic zone in the middle¯upper troposphere is detected in all the 6 models,and this change in the Southern Hemi¯ sphere would be more significant.The changes of the baroclinic zone reflect the similar changes of storm track to some extent, which supports for the conclusion of possible poleward shift of the two storm tracks.That could be a significant reduction in EC activities over the Northern Hemisphere under RCP4.5,while the poleward movements of baroclinic zone and storm path would cause more remarkable reduction of EC activities over the lower latitudes in the future.%利用 CMIP5(Coupled Model Intercomparison Project Phase 5)的6个气候耦合模式中等排放情景———RCP4•5(典型浓度路径4•5)下的模拟结果对北半球温带气旋数目、风暴路径和强度的未来变化进行了研究分析。结果表明:(1)相对于20

  4. A framework for web browser-based medical simulation using WebGL.

    Science.gov (United States)

    Halic, Tansel; Ahn, Woojin; De, Suvranu

    2012-01-01

    This paper presents a web browser-based software framework that provides accessibility, portability, and platform independence for medical simulation. Typical medical simulation systems are restricted to the underlying platform and device, which limits widespread use. Our framework allows realistic and efficient medical simulation using only the web browser for anytime anywhere access using a variety of platforms ranging from desktop PCs to tablets. The framework consists of visualization, simulation, and hardware integration modules that are fundamental components for multimodal interactive simulation. Benchmark tests are performed to validate the rendering and computing performance of our framework with latest web browsers including Chrome and Firefox. The results are quite promising opening up the possibility of developing web-based medical simulation technology.

  5. A Typology of Multi-sided Platforms

    DEFF Research Database (Denmark)

    Staykova, Kalina Stefanova; Damsgaard, Jan

    2015-01-01

    which evolved several steps into being multi-sided (Facebook). Our analysis shows a structural difference between one-sided, two-sided and multi-sided platforms and that platforms consist of a core and potentially also a periphery. The sides of a platform and the ties which connect them can be arranged...

  6. Entity Framework 4.0 Recipes A Problem-solution Approach

    CERN Document Server

    Tenny, L

    2010-01-01

    Entity Framework 4.0 Recipes provides an exhaustive collection of ready-to-use code solutions for Microsoft's Entity Framework, Microsoft's vision for the future of data access. Entity Framework is a model-centric data access platform with an ocean of new concepts and patterns for developers to learn. With this book, you will learn the core concepts of Entity Framework through a broad range of clear and concise solutions to everyday data access tasks. Armed with this experience, you will be ready to dive deep into Entity Framework, experiment with new approaches, and develop ways to solve even

  7. The data platform of national special environment and disaster field observation stations based on grid environment

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    The Data Platform of Resource and Environment-whose data mainly come from field observation stations,spatial observations,and internet service institutions-is the base of data analysis and model simulation in geoscience research in China.Among this integrated data platform,the tasks of the data platform of field observation stations are principally data collection,management,assimilation,and share service.Taking into consideration the distributing characteristics of the data sources and the service objects,the authors formulated the framework of the field observation stations’ data platform based on the grid technology and designed its operating processes.The authors have further defined and analyzed the key functions and implementing techniques for each module.In a Linux operating system,validation tests for the data platform’s function on data replication,data synchronization,and unified data service have been conducted under an environment that of the simulating field stations.

  8. Investigation of the effects of platform motion on the aerodynamics of a floating offshore wind turbine

    Institute of Scientific and Technical Information of China (English)

    万德成

    2016-01-01

    Along with the flourishing of the wind energy industry, floating offshore wind turbines have aroused much interest among the academia as well as enterprises. In this paper, the effects of the supporting platform motion on the aerodynamics of a floating wind turbine are studied using the open source CFD framework OpenFOAM. The platform motion responses, including surge, heave and pitch, are superimposed onto the rotation of the wind turbine. Thrust and torque on the wind turbine are compared and analysed for the cases of different platform motion patterns together with the flow field. It is shown that the movement of the supporting platform can have large influences on a floating offshore wind turbine and thus needs to be considered carefully during the design process.

  9. A Caregiver Support Platform within the Scope of an Ambient Assisted Living Ecosystem

    Directory of Open Access Journals (Sweden)

    Angelo Costa

    2014-03-01

    Full Text Available The Ambient Assisted Living (AAL area is in constant evolution, providing new technologies to users and enhancing the level of security and comfort that is ensured by house platforms. The Ambient Assisted Living for All (AAL4ALL project aims to develop a new AAL concept, supported on a unified ecosystem and certification process that enables a heterogeneous environment. The concepts of Intelligent Environments, Ambient Intelligence, and the foundations of the Ambient Assisted Living are all presented in the framework of this project. In this work, we consider a specific platform developed in the scope of AAL4ALL, called UserAccess. The architecture of the platform and its role within the overall AAL4ALL concept, the implementation of the platform, and the available interfaces are presented. In addition, its feasibility is validated through a series of tests.

  10. Using fuzzy analytical hierarchy process (AHP to evaluate web development platform

    Directory of Open Access Journals (Sweden)

    Ahmad Sarfaraz

    2012-01-01

    Full Text Available Web development is plays an important role on business plans and people's lives. One of the key decisions in which both short-term and long-term success of the project depends is choosing the right development platform. Its criticality can be judged by the fact that once a platform is chosen, one has to live with it throughout the software development life cycle. The entire shape of the project depends on the language, operating system, tools, frameworks etc., in short the web development platform chosen. In addition, choosing the right platform is a multi criteria decision making (MCDM problem. We propose a fuzzy analytical hierarchy process model to solve the MCDM problem. We try to tap the real-life modeling potential of fuzzy logic and conjugate it with the commonly used powerful AHP modeling method.

  11. The SOPHY Framework

    DEFF Research Database (Denmark)

    Laursen, Karl Kaas; Pedersen, Martin Fejrskov; Bendtsen, Jan Dimon;

    The goal of the Sophy framework (Simulation, Observation and Planning in Hybrid Systems) is to implement a multi-level framework for description, simulation, observation, fault detection and recovery, diagnosis and autonomous planning in distributed embedded hybrid systems. A Java-based distributed...

  12. Overlooking the Conceptual Framework

    Science.gov (United States)

    Leshem, Shosh; Trafford, Vernon

    2007-01-01

    The conceptual framework is alluded to in most serious texts on research, described in some and fully explained in few. However, examiners of doctoral theses devote considerable attention to exploring its function within social science doctoral vivas. A literature survey explores how the conceptual framework is itself conceptualised and explained.…

  13. Frameworks in CS1

    DEFF Research Database (Denmark)

    Christensen, Henrik Bærbak; Caspersen, Michael Edelgaard

    2002-01-01

    In this paper we argue that introducing object-oriented frameworks as subject already in the CS1 curriculum is important if we are to train the programmers of tomorrow to become just as much software reusers as software producers. We present a simple, graphical, framework that we have successfully...

  14. Framework and new conceptualisations

    DEFF Research Database (Denmark)

    Søndergaard, Dorte Marie

    This paper introduces the research and new conceptual framework developed by eXbus: Exploring Bullying in Schools from 2007-2012.......This paper introduces the research and new conceptual framework developed by eXbus: Exploring Bullying in Schools from 2007-2012....

  15. Unicam Activity Framework (UAF)

    Science.gov (United States)

    Gagliardi, R.; Mauri, M.; Polzonetti, A.

    2016-01-01

    This presentation illustrates the framework of processing performance of the faculty of the University of Camerino. The evaluation criteria are explained and the technological structure that allows automatic performance assessment available online anywhere and anytime. The designed framework is usually applied to the performance evaluation of…

  16. Demand forecasting and information platform in tourism

    Science.gov (United States)

    Li, Yue; Jiang, Qi-Jie

    2017-05-01

    Information asymmetry and the bullwhip effect have been serious problems in the tourism supply chain. Based on platform theory, this paper established a mathematical model to explore the inner mechanism of a platform's influence on stakeholders' ability to forecast demand in tourism. Results showed that the variance of stakeholders' demand predictions with a platform was smaller than the variance without a platform, which meant that a platform would improve predictions of demand for stakeholders. The higher information-processing ability of the platform also had other effects on demand forecasting. Research on the inner logic of the platform's influence on stakeholders has important theoretical and realistic value. This area is worthy of further study.

  17. Platform economy in Denmark – precarious employment?

    DEFF Research Database (Denmark)

    Rasmussen, Stine; Madsen, Per Kongshøj

    This paper takes a labour market perspective on the emerging concept of the 'sharing economy' or 'platform economy', which we use as a more appropriate term for the phenomenon. Platform economy is in the article understood as those business models that have emerged since the millennium, where...... digital platforms serve as the link between persons wanting to make use of certain activities, services etc. and those owning them and we only have an interest in the work-related platforms. That means platforms, where paid work is offered and demanded. International examples of this new phenomenon...... of this paper is to examine the work-related activities in the Danish platform economy and discuss whether and to what extent these activities are to be considered precarious forms of employment. The paper begins with a discussion of the terms sharing economy and platform economy in order to reach...

  18. Simatik : Aplikasi Simulasi Bank Soal Tes Potensi Akademik (TPA Berbasis Multi Platform

    Directory of Open Access Journals (Sweden)

    Made Hendra Yudha Saputra

    2017-01-01

    Full Text Available Abstrak---Penelitian ini bertujuan untuk : (1 menghasilkan rancang bangun dan implementasi Simatik : Aplikasi Simulasi Bank Soal Tes Potensi Akademik (TPA Berbasis Multi Platform, (2 Mengetahui respon dari Pengguna terhadap Simatik : Aplikasi Simulasi Bank Soal Tes Potensi Akademik (TPA Berbasis Multi Platform. Dalam perancangannya, aplikasi ini akan menggunakan arsitektur client-server untuk melakukan proses pertukaran data. Perancangan dilakukan dengan menggunakan model fungsional berupa UML. Model fungsional berupa UML tersebut diimplementasikan dalam sebuah framework yaitu Phonegap dengan bahasa pemrograman HTML5. Untuk mengetahui respon terhadap Simatik : Aplikasi Simulasi Bank Soal Tes Potensi Akademik (TPA Berbasis Multi Platform ini diperoleh dengan menggunakan metode angket. Hasil akhirnya yaitu berupa Aplikasi Simatik berbasis Multi Platform yang dapat diinstall pada perangkat mobile untuk digunakan dalam latihan soal-soal yang terkait dengan Tes Potensi Akademik (TPA. Berdasarkan hasil uji usability, aplikasi Simatik berbasis Multi Platform ini mendapatkan persentase hasil sebesar 95,6 % dengan kategori sangat baik yang berarti dalam pengoperasiannya aplikasi ini mudah untuk digunakan dan dapat berfungsi sesuai dengan fungsi seharusnya. Kata Kunci : Phonegap, Multi Platform, Client Server, Mobile, Tes Potensi Akademik (TPA, Simatik   Abstract--- This research is purpose to : (1 produce generate design and implementation Simatik : Aplikasi Simulasi Bank Soal Tes Potensi Akademik (TPA Berbasis Multi Platform (2 To knowing the response of users to Simatik : Aplikasi Simulasi Bank Soal Tes Potensi Akademik (TPA Berbasis Multi Platform. In its design, this application will use the client-server architecture to make the exchange process of data. The design were done by using a functional model UML form. The functional model UML form is implemented within a framework that is phonegap with HTML 5 programming languages. To determine the

  19. REEF: Retainable Evaluator Execution Framework.

    Science.gov (United States)

    Weimer, Markus; Chen, Yingda; Chun, Byung-Gon; Condie, Tyson; Curino, Carlo; Douglas, Chris; Lee, Yunseong; Majestro, Tony; Malkhi, Dahlia; Matusevych, Sergiy; Myers, Brandon; Narayanamurthy, Shravan; Ramakrishnan, Raghu; Rao, Sriram; Sears, Russell; Sezgin, Beysim; Wang, Julia

    2015-01-01

    Resource Managers like Apache YARN have emerged as a critical layer in the cloud computing system stack, but the developer abstractions for leasing cluster resources and instantiating application logic are very low-level. This flexibility comes at a high cost in terms of developer effort, as each application must repeatedly tackle the same challenges (e.g., fault-tolerance, task scheduling and coordination) and re-implement common mechanisms (e.g., caching, bulk-data transfers). This paper presents REEF, a development framework that provides a control-plane for scheduling and coordinating task-level (data-plane) work on cluster resources obtained from a Resource Manager. REEF provides mechanisms that facilitate resource re-use for data caching, and state management abstractions that greatly ease the development of elastic data processing work-flows on cloud platforms that support a Resource Manager service. REEF is being used to develop several commercial offerings such as the Azure Stream Analytics service. Furthermore, we demonstrate REEF development of a distributed shell application, a machine learning algorithm, and a port of the CORFU [4] system. REEF is also currently an Apache Incubator project that has attracted contributors from several instititutions.

  20. Education Platform at ZDM8.

    Science.gov (United States)

    Lyman Gingerich, Jamie S; Pickart, Michael A; Pierret, Chris

    2016-04-01

    Interest among the zebrafish community in education and science accessibility for all ages has increased. At the 8th Annual Zebrafish Disease Models Conference (ZDM8), a specifically designed session enabled professional scientists, educators, and students to have a venue to present their science, discuss ideas in education, and partner to navigate a scientific meeting as an educational experience. This meeting report describes the format of the Platform Session as well as challenges and future plans to leverage impact of conferences on the local communities.