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Sample records for platform happ volume

  1. Cryogenic nanosecond and picosecond high average and peak power(HAPP) pump lasers for ultrafast applications

    Institute of Scientific and Technical Information of China (English)

    David C.Brown; Sten Tornegrd; Joseph Kolis

    2016-01-01

    Using cryogenic laser technology, it is now possible to design and demonstrate lasers that have concomitant high average and peak powers, with near-diffraction-limited beam quality. We refer to these new laser systems as HAPP lasers. In this paper, we review important laser crystal materials properties at cryogenic temperature, with an emphasis on Yb lasers, and discuss the important design considerations, including the laser-induced damage threshold, nonlinear effects and thermal effects. A comprehensive model is presented to describe diode pulsed pumping with arbitrary duration and repetition rate, and is used with the Frantz–Nodvik equation to describe, to first order, the performance of HAPP laser systems. A computer code with representative results is also described.

  2. Development of deployable structures for large space platforms. Volume 2: Design development

    Science.gov (United States)

    Greenberg, H. S.

    1983-01-01

    Design evolution, test article design, test article mass properties, and structural analysis of deployable platform systems are discussed. Orbit transfer vehicle (OTV) hangar development, OTV hangar concept selection, and manned module development are discussed. Deployable platform systems requirements, material data base, technology development needs, concept selection and deployable volume enclosures are also discussed.

  3. Chronic apocynin treatment attenuates beta amyloid plaque size and microglial number in hAPP(751(SL mice.

    Directory of Open Access Journals (Sweden)

    Melinda E Lull

    Full Text Available BACKGROUND: NADPH oxidase is implicated in neurotoxic microglial activation and the progressive nature of Alzheimer's Disease (AD. Here, we test the ability of two NADPH oxidase inhibitors, apocynin and dextromethorphan (DM, to reduce learning deficits and neuropathology in transgenic mice overexpressing human amyloid precursor protein with the Swedish and London mutations (hAPP(751(SL. METHODS: Four month old hAPP(751(SL mice were treated daily with saline, 15 mg/kg DM, 7.5 mg/kg DM, or 10 mg/kg apocynin by gavage for four months. RESULTS: Only hAPP(751(SL mice treated with apocynin showed reduced plaque size and a reduction in the number of cortical microglia, when compared to the saline treated group. Analysis of whole brain homogenates from all treatments tested (saline, DM, and apocynin demonstrated low levels of TNFα, protein nitration, lipid peroxidation, and NADPH oxidase activation, indicating a low level of neuroinflammation and oxidative stress in hAPP(751(SL mice at 8 months of age that was not significantly affected by any drug treatment. Despite in vitro analyses demonstrating that apocynin and DM ameliorate Aβ-induced extracellular superoxide production and neurotoxicity, both DM and apocynin failed to significantly affect learning and memory tasks or synaptic density in hAPP(751(SL mice. To discern how apocynin was affecting plaque levels (plaque load and microglial number in vivo, in vitro analysis of microglia was performed, revealing no apocynin effects on beta-amyloid (Aβ phagocytosis, microglial proliferation, or microglial survival. CONCLUSIONS: Together, this study suggests that while hAPP(751(SL mice show increases in microglial number and plaque load, they fail to exhibit elevated markers of neuroinflammation consistent with AD at 8 months of age, which may be a limitation of this animal model. Despite absence of clear neuroinflammation, apocynin was still able to reduce both plaque size and microglial number

  4. OTEC platform configuration and integration. Volume II. Technical concept. Final report

    Energy Technology Data Exchange (ETDEWEB)

    None

    1978-07-07

    The configuration, integration, and evaluation studies performed in the first phase of this contract resulted in a ranking of the most feasible platform candidates for commercial OTEC applications. On the basis of the results obtained from three individual contractors performing the same study, the Department of Energy made selections of two platform hulls for each contractor for conceptual designs. For Phase-II studies, M. Rosenblatt and Son, Inc. (MR and S) project team was given the SPAR and SPHERE platforms to perform not only conceptual designs for, but also cost and time schedules and sensitivity analyses. This is the second volume of a three-volume MR and S report, and it presents the results of conceptual designs for the two platforms, the facilities and equipment required for construction, deployment, and operation of these platforms, and cost estimates and time schedules. All conceptual design work is performed for the baseline site on West Coast of Florida. The cost differentials and other considerations involved with deploying the platforms in the New Orleans and Puerto Rico sites are also presented. As an end product of the complete study, the costs for the SPAR and the SPHERE platforms are reported both in terms of acquisition costs in 1978 dollars and life cycle costs in dollars per kilowatt.

  5. Liposome-based liquid handling platform featuring addition, mixing, and aliquoting of femtoliter volumes.

    Directory of Open Access Journals (Sweden)

    Hideaki Shiomi

    Full Text Available This paper describes the utilization of giant unilamellar vesicles (GUVs as a platform for handling chemical and biochemical reagents. GUVs with diameters of 5 to 10 µm and containing chemical/biochemical reagents together with inert polymers were fused with electric pulses (electrofusion. After reagent mixing, the fused GUVs spontaneously deformed to a budding shape, separating the mixed solution into sub-volumes. We utilized a microfluidic channel and optical tweezers to select GUVs of interest, bring them into contact, and fuse them together to mix and aliquot the reaction product. We also show that, by lowering the ambient temperature close to the phase transition temperature Tm of the lipid used, daughter GUVs completely detached (fission. This process performs all the liquid-handing features used in bench-top biochemistry using the GUV, which could be advantageous for the membrane-related biochemical assays.

  6. SpringSaLaD: A Spatial, Particle-Based Biochemical Simulation Platform with Excluded Volume.

    Science.gov (United States)

    Michalski, Paul J; Loew, Leslie M

    2016-02-02

    We introduce Springs, Sites, and Langevin Dynamics (SpringSaLaD), a comprehensive software platform for spatial, stochastic, particle-based modeling of biochemical systems. SpringSaLaD models biomolecules in a coarse-grained manner as a group of linked spherical sites with excluded volume. This mesoscopic approach bridges the gap between highly detailed molecular dynamics simulations and the various methods used to study network kinetics and diffusion at the cellular level. SpringSaLaD is a standalone tool that supports model building, simulation, visualization, and data analysis, all through a user-friendly graphical user interface that should make it more accessible than tools built into more comprehensive molecular dynamics infrastructures. Importantly, for bimolecular reactions we derive an exact expression relating the macroscopic on-rate to the various microscopic parameters with the inclusion of excluded volume; this makes SpringSaLaD more accurate than other tools, which rely on approximate relationships between these parameters.

  7. Performance of children with social communication disorder on the Happé Strange Stories: Physical and mental state responses and relationship to language ability.

    Science.gov (United States)

    Freed, Jenny; McBean, Kirsty; Adams, Catherine; Lockton, Elaine; Nash, Marysia; Law, James

    2015-01-01

    This study investigated whether a modified scoring method was useful for examining the ability of children with social communication disorder (CwSCD) to understand non-literal language and use mental state responses on the Happé Strange Stories (HSS) task. CwSCD and a control group of children with typical language development (CwTLD) completed 10 of the original HSS. CwSCD scored significantly lower on the HSS task than did CwTLD and were much less likely to produce mental state responses. There was a high level of inter-rater reliability (Weighted Kappa=0.907) across data from both groups. HSS performance and language ability correlated significantly for CwSCD. A regression model with age, nonverbal intelligence, receptive and expressive language as predictors explained 55.2% of the variance in HSS ability for CwSCD. The results suggest that the HSS have potential to be used as a clinical assessment to investigate high-level language and ability to infer intent in CwSCD. Readers will be able to describe a modified scoring method for the Happé Strange Stories task. Readers will be able to identify areas of impairment for children with social communication disorder. Readers will identify how these areas of impairment have an effect on ability to understand non-literal language and produce mental state responses on the Happé Strange Stories task. Copyright © 2015 Elsevier Inc. All rights reserved.

  8. OTEC platform configuration and integration. Appendixes to Volume II. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Price, David

    1978-07-07

    Detailed information and conceptual design drawings for the SPAR and SPHERE platforms for an OTEC commercial plant are presented. A work breakdown structure and a detailed estimate of the SPAR platform weight are included. (WHK)

  9. Behavioural inflexibility in a comorbid rat model of striatal ischemic injury and mutant hAPP overexpression.

    Science.gov (United States)

    Levit, Alexander; Regis, Aaron M; Garabon, Jessica R; Oh, Seung-Hun; Desai, Sagar J; Rajakumar, Nagalingam; Hachinski, Vladimir; Agca, Yuksel; Agca, Cansu; Whitehead, Shawn N; Allman, Brian L

    2017-08-30

    Alzheimer disease (AD) and stroke coexist and interact; yet how they interact is not sufficiently understood. Both AD and basal ganglia stroke can impair behavioural flexibility, which can be reliably modeled in rats using an established operant based set-shifting test. Transgenic Fischer 344-APP21 rats (TgF344) overexpress pathogenic human amyloid precursor protein (hAPP) but do not spontaneously develop overt pathology, hence TgF344 rats can be used to model the effect of vascular injury in the prodromal stages of Alzheimer disease. We demonstrate that the injection of endothelin-1 (ET1) into the dorsal striatum of TgF344 rats (Tg-ET1) produced an exacerbation of behavioural inflexibility with a behavioural phenotype that was distinct from saline-injected wildtype & TgF344 rats as well as ET1-injected wildtype rats (Wt-ET1). In addition to profiling the types of errors made, interpolative modeling using logistic exposure-response regression provided an informative analysis of the timing and efficiency of behavioural flexibility. During set-shifting, Tg-ET1 committed fewer perseverative errors than Wt-ET1. However, Tg-ET1 committed significantly more regressive errors and had a less efficient strategy change than all other groups. Thus, behavioural flexibility was more vulnerable to striatal ischemic injury in TgF344 rats. Copyright © 2017 Elsevier B.V. All rights reserved.

  10. Transaction-based building controls framework, Volume 2: Platform descriptive model and requirements

    Energy Technology Data Exchange (ETDEWEB)

    Akyol, Bora A. [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Haack, Jereme N. [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Carpenter, Brandon J. [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Katipamula, Srinivas [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Lutes, Robert G. [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Hernandez, George [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)

    2015-07-31

    Transaction-based Building Controls (TBC) offer a control systems platform that provides an agent execution environment that meets the growing requirements for security, resource utilization, and reliability. This report outlines the requirements for a platform to meet these needs and describes an illustrative/exemplary implementation.

  11. OTEC platform configuration and integration study. Volume I. Systems engineering and integration. Final report

    Energy Technology Data Exchange (ETDEWEB)

    None

    1978-04-01

    The economic success of an Ocean Thermal Energy Conversion (OTEC) system is highly dependent on a platform which provides adequate support for the power system, accommodates reliably the cold water pipe, and is most cost effective. The results of a study conducted for the Department of Energy to assess six generic types of platforms to determine the most satisfactory platform for severl potential sites are presented. The six platform configurations are ship, circular barge, semi-submersible, Tuned Sphere, submersible, and spar. These represent directional and symmetric types of platforms which operate on the surface, at the interface, and submerged. The five sites for this study were primarily New Orleans, Keahole Point (Hawaii), Brazil, and secondarily Key West and Puerto Rico. Electrical transmission of energy by submarine cable is the planned form of energy transmission for all sites except Brazil, where chemical conversion is to be the method of transmission. This study is devoted to the platform (or ocean systems) of the OTEC plant which is chiefly comprised of the hull and structure, the seawater system, the position control system, and miscellaneous support/assembly systems. The principal elements in the work breakdown structure for the commercial plants are presented. The assessment of the six platform configurations was conducted utilizing a baseline plan (100-MW(e) (Net)) and site (New Orleans) with variations from the baseline to cover the range of interested platforms and sites.

  12. Development of deployable structures for large space platform systems, volume 1

    Science.gov (United States)

    1982-01-01

    Generic deployable spacecraft configurations and deployable platform systems concepts were identified. Sizing, building block concepts, orbiter packaging, thermal analysis, cost analysis, and mass properties analysis as related to platform systems integration are considered. Technology needs are examined and the major criteria used in concept selection are delineated. Requirements for deployable habitat modules, tunnels, and OTV hangars are considered.

  13. ONGOING ELECTROENCEPHALOGRAPHIC ACTIVITY ASSOCIATED WITH CORTICAL AROUSAL IN TRANSGENIC PDAPP MICE (hAPP V717F).

    Science.gov (United States)

    Del Percio, Claudio; Drinkenburg, Wilhelmus; Lopez, Susanna; Limatola, Cristina; Bastlund, Jesper F; Christensen, Ditte Zerlang; Pedersen, Jan T; Forloni, Gianluigi; Frasca, Angelisa; Noè, Francesco M; Bentivoglio, Marina; Fabene, Paolo F; Bertini, Giuseppe; Colavito, Valeria; Dix, Sophie; Ferri, Raffaele; Bordet, Regis; Richardso, Jill C; Babiloni, Claudio

    2017-07-04

    It has been shown that theta (6-10 Hz) and delta (1-6 Hz) ongoing electroencephalographic (EEG) rhythms revealed variations in the cortical arousal in C57 Wild Type (WT) mice during cage exploration (active condition) compared to awake quiet behavior (passive condition; IMI PharmaCog project, www.pharmacog.eu). Test if these EEG rhythms might be abnormal in old PDAPP mice modeling Alzheimer's disease (AD) with a hAPP Indiana V717F mutation (They show abnormal neural transmission, cognitive deficits, and brain accumulation of Aβ1-42). Ongoing EEG rhythms were recorded by a frontoparietal bipolar channel in 15 PDAPP and 23 WT C57 male mice (mean age of 22.8 months ±0.4 and 0.3 standard error, respectively). EEG absolute power (density) was calculated. Frequency and amplitude of individual delta and theta frequency (IDF and ITF) peaks were considered during passive and active states in the wakefulness. Compared with the WT group, the PDAPP group showed higher frequency of the IDF during the passive condition and lower frequency of the ITF during the active state. Furthermore, the WT but not PDAPP group showed significant changes in the frontoparietal EEG power (IDF, ITF) during active over passive state. PDAPP mice were characterized by less changes in the brain arousal during an active state as revealed by frontoparietal EEG rhythms. Future studies will have to cross-validate the present results on large animal groups, clarify the neurophysiological underpinning of the effect, and test if the disease modifying drugs against AD amyloidosis normalize those candiate EEG biomarkers in PDAPP mice. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  14. Modular OTEC platforms, SKSS designs. Volume I. Executive summary. Final report

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-02-29

    One of the possible options for generating electrical energy from ocean thermal gradients requires the use of a floating offshore platform. The platform would contain all OTEC (Ocean Thermal Energy Conversion) systems and power cycle components and consist of the hull, seawater, station-keeping, platform service, and mission support subsystems. It would be stationed at one of the designated OTEC sites, and would transmit the generated electricity to the shore power networks by means of an electrical transmission cable. The objective of the present study is to investigate the station-keeping subsystem (SKSS) requirements and develop preliminary SKSS designs for the two Modular Experiment Plant (MEP) candidates of 10/40 MW/sub e/ capacity for deployment at a specific site. The two MEP hull candidates are a Barge type platform and a Spar shaped hull with external heat exchangers. The specific site assigned for this study is Puerto Rico. The preliminary SKSS designs are developed for both platforms as follows: (1) an 8-leg spread catenary mooring system for the Spar, and (2) a 12-leg spread catenary mooring system for the Barge. Applicability of these designs to larger capacity commercial OTEC platforms is also investigated.

  15. Geosynchronous platform definition study. Volume 6: Geosynchronous program evaluation and recommendations

    Science.gov (United States)

    Myers, H. L.

    1973-01-01

    The programmatic analyses conducted to achieve the objectives of the study are presented. The characteristics are examined of alternate geosynchronous programs based on servicing concepts, geosynchronous platform configurations, and equipment definitions which have evolved during the study. The logistics support necessary to carry out programs using these systems is defined considering alternate approaches for on-orbit servicing. The costs of the resultant programs are then determined and the alternate program approaches compared. Conventional programs with expendable satellites are also defined to the extent necessary to permit comparison with on-orbit serviced platform programs.

  16. Development of deployable structures for large space platform systems. Volume 1: Executive summary

    Science.gov (United States)

    Greenberg, H. S.

    1983-01-01

    The preponderance of study effort was devoted toward the deployable platform systems study which culminated in the detailed design of a ground test article for future development testing. This design is representative of a prototype square-truss, single-fold building-block design that can construct deployable platform structures. This prototype design was selected through a comprehensive and traceable selection process applied to eight competitive designs. The selection process compared the competitive designs according to seven major selection criteria, i.e., design versatility, cost, thermal stability, meteoroid impact significance, reliability, performance predictability, and orbiter integration suitability. In support of the foregoing, a materials data base, and platform systems technology development needs were established. An erectable design of an OTV hangar was selected and recommended for further design development. This design was selected from five study-developed competitive single-fold and double-fold designs including hard-shell and inflatable designs. Also, two deployable manned module configurations, i.e., a hard-shell and an inflatable design were each developed to the same requirements as the composite of two Space station baseline habitat modules.

  17. Ocean Thermal Energy Conversion (OTEC) platform configuration and integration. Volume II. Conceptual design. Final report

    Energy Technology Data Exchange (ETDEWEB)

    None

    1978-06-01

    The purpose of this project is to evaluate six candidate hullforms as candidates for the OTEC commercial plant. This volume is a summary of the conceptual design including facility requirements, cost, schedule, and site sensitivity. Two OTEC commercial plant configurations are considered in this study: the ship and the semi-submersible. Engineering drawings are presented. (WHR)

  18. A high-throughput platform for low-volume high-temperature/pressure sealed vessel solvent extractions

    Energy Technology Data Exchange (ETDEWEB)

    Damm, Markus [Christian Doppler Laboratory for Microwave Chemistry (CDLMC) and Institute of Chemistry, Karl-Franzens-University Graz, Heinrichstrasse 28, A-8010 Graz (Austria); Kappe, C. Oliver, E-mail: oliver.kappe@uni-graz.at [Christian Doppler Laboratory for Microwave Chemistry (CDLMC) and Institute of Chemistry, Karl-Franzens-University Graz, Heinrichstrasse 28, A-8010 Graz (Austria)

    2011-11-30

    Highlights: Black-Right-Pointing-Pointer Parallel low-volume coffee extractions in sealed-vessel HPLC/GC vials. Black-Right-Pointing-Pointer Extractions are performed at high temperatures and pressures (200 Degree-Sign C/20 bar). Black-Right-Pointing-Pointer Rapid caffeine determination from the liquid phase. Black-Right-Pointing-Pointer Headspace analysis of volatiles using solid-phase microextraction (SPME). - Abstract: A high-throughput platform for performing parallel solvent extractions in sealed HPLC/GC vials inside a microwave reactor is described. The system consist of a strongly microwave-absorbing silicon carbide plate with 20 cylindrical wells of appropriate dimensions to be fitted with standard HPLC/GC autosampler vials serving as extraction vessels. Due to the possibility of heating up to four heating platforms simultaneously (80 vials), efficient parallel analytical-scale solvent extractions can be performed using volumes of 0.5-1.5 mL at a maximum temperature/pressure limit of 200 Degree-Sign C/20 bar. Since the extraction and subsequent analysis by either gas chromatography or liquid chromatography coupled with mass detection (GC-MS or LC-MS) is performed directly from the autosampler vial, errors caused by sample transfer can be minimized. The platform was evaluated for the extraction and quantification of caffeine from commercial coffee powders assessing different solvent types, extraction temperatures and times. For example, 141 {+-} 11 {mu}g caffeine (5 mg coffee powder) were extracted during a single extraction cycle using methanol as extraction solvent, whereas only 90 {+-} 11 were obtained performing the extraction in methylene chloride, applying the same reaction conditions (90 Degree-Sign C, 10 min). In multiple extraction experiments a total of {approx}150 {mu}g caffeine was extracted from 5 mg commercial coffee powder. In addition to the quantitative caffeine determination, a comparative qualitative analysis of the liquid phase coffee

  19. Floating substructure flexibility of large-volume 10MW offshore wind turbine platforms in dynamic calculations

    Science.gov (United States)

    Borg, Michael; Melchior Hansen, Anders; Bredmose, Henrik

    2016-09-01

    Designing floating substructures for the next generation of 10MW and larger wind turbines has introduced new challenges in capturing relevant physical effects in dynamic simulation tools. In achieving technically and economically optimal floating substructures, structural flexibility may increase to the extent that it becomes relevant to include in addition to the standard rigid body substructure modes which are typically described through linear radiation-diffraction theory. This paper describes a method for the inclusion of substructural flexibility in aero-hydro-servo-elastic dynamic simulations for large-volume substructures, including wave-structure interactions, to form the basis of deriving sectional loads and stresses within the substructure. The method is applied to a case study to illustrate the implementation and relevance. It is found that the flexible mode is significantly excited in an extreme event, indicating an increase in predicted substructure internal loads.

  20. Determination of blood leukocyte concentration with constant volume acquisition on a flow cytometer is comparable to individualized single platform testing with beads as internal reference standard

    DEFF Research Database (Denmark)

    Hansen, Susan; Dahl, Ronald; Hoffmann, Hans Jürgen

    2008-01-01

    Flow cytometers have a constant flow rate. This enables flow cytometers to measure leukocyte concentrations in a determined volume by acquiring data at a fixed rate over a fixed time and is called constant volume acquisition (CVA). The volume aspirated by a FACS Calibur flow cytometer in 4 min...... at a high rate has a median of 163 microl (IQR 156-170) with TruCount tubes. Leukocyte concentrations of 26 healthy volunteers were measured twice on up to four occasions with a Bürker-Türk chamber, by single platform technology (SPT) with TruCount tubes and on the same data set using CVA. Total leukocyte...... concentrations determined by CVA correlated better with measurements in a Bürker-Türk (BT) chamber than with SPT. Concentrations determined with CVA were 1.86% higher than with BT whereas SPT data were 5.35% higher than BT (pCVA (p

  1. Around the laboratories: Rutherford: Successful tests on bubble chamber target technique; Stanford (SLAC): New storage rings proposal; Berkeley: The HAPPE project to examine cosmic rays with superconducting magnets; The 60th birthday of Professor N.N. Bogolyubov; Argonne: Performance of the automatic film measuring system POLLY II

    CERN Multimedia

    1969-01-01

    Around the laboratories: Rutherford: Successful tests on bubble chamber target technique; Stanford (SLAC): New storage rings proposal; Berkeley: The HAPPE project to examine cosmic rays with superconducting magnets; The 60th birthday of Professor N.N. Bogolyubov; Argonne: Performance of the automatic film measuring system POLLY II

  2. Geosynchronous platform definition study. Volume 4, Part 1: Traffic analysis and system requirements for the baseline traffic model

    Science.gov (United States)

    1973-01-01

    The traffic analyses and system requirements data generated in the study resulted in the development of two traffic models; the baseline traffic model and the new traffic model. The baseline traffic model provides traceability between the numbers and types of geosynchronous missions considered in the study and the entire spectrum of missions foreseen in the total national space program. The information presented pertaining to the baseline traffic model includes: (1) definition of the baseline traffic model, including identification of specific geosynchronous missions and their payload delivery schedules through 1990; (2) Satellite location criteria, including the resulting distribution of the satellite population; (3) Geosynchronous orbit saturation analyses, including the effects of satellite physical proximity and potential electromagnetic interference; and (4) Platform system requirements analyses, including satellite and mission equipment descriptions, the options and limitations in grouping satellites, and on-orbit servicing criteria (both remotely controlled and man-attended).

  3. Ocean thermal energy conversion (OTEC) platform configuration and integration. Final report. Volume I. Systems requirements and evaluation

    Energy Technology Data Exchange (ETDEWEB)

    None

    1978-06-01

    Studies leading to the development of two 400 MW Offshore Thermal Energy Conversion Commercial Plants are presented. This volume includes a summary of three tasks: task IIA--systems evaluation and requirements; task IIB--evaluation plan; task III--technology review; and task IV--systems integration evaluation. Task IIA includes the definition of top level requirements and an assessment of factors critical to the selection of hull configuration and size, quantification of payload requirements and characteristics, and sensitivity of system characteristics to site selection. Task IIB includes development of a methodology for systematically evaluating the candidate hullforms, based on interrelationships and priorities developed during task IIA. Task III includes the assessment of current technology and identification of deficiencies in relation to OTEC requirements and the development of plans to correct such deficiencies. Task IV involves the formal evaluation of the six candidate hullforms in relation to sit and plant capacity to quantify cost/size/capability relationships, leading to selection of an optimum commercial plant. (WHK)

  4. Programmatic implications of implementing the relational algebraic capacitated location (RACL) algorithm outcomes on the allocation of laboratory sites, test volumes, platform distribution and space requirements.

    Science.gov (United States)

    Cassim, Naseem; Smith, Honora; Coetzee, Lindi M; Glencross, Deborah K

    2017-01-01

    CD4 testing in South Africa is based on an integrated tiered service delivery model that matches testing demand with capacity. The National Health Laboratory Service has predominantly implemented laboratory-based CD4 testing. Coverage gaps, over-/under-capacitation and optimal placement of point-of-care (POC) testing sites need investigation. We assessed the impact of relational algebraic capacitated location (RACL) algorithm outcomes on the allocation of laboratory and POC testing sites. The RACL algorithm was developed to allocate laboratories and POC sites to ensure coverage using a set coverage approach for a defined travel time (T). The algorithm was repeated for three scenarios (A: T = 4; B: T = 3; C: T = 2 hours). Drive times for a representative sample of health facility clusters were used to approximate T. Outcomes included allocation of testing sites, Euclidian distances and test volumes. Additional analysis included platform distribution and space requirement assessment. Scenarios were reported as fusion table maps. Scenario A would offer a fully-centralised approach with 15 CD4 laboratories without any POC testing. A significant increase in volumes would result in a four-fold increase at busier laboratories. CD4 laboratories would increase to 41 in scenario B and 61 in scenario C. POC testing would be offered at two sites in scenario B and 20 sites in scenario C. The RACL algorithm provides an objective methodology to address coverage gaps through the allocation of CD4 laboratories and POC sites for a given T. The algorithm outcomes need to be assessed in the context of local conditions.

  5. Programmatic implications of implementing the relational algebraic capacitated location (RACL algorithm outcomes on the allocation of laboratory sites, test volumes, platform distribution and space requirements

    Directory of Open Access Journals (Sweden)

    Naseem Cassim

    2017-02-01

    Full Text Available Introduction: CD4 testing in South Africa is based on an integrated tiered service delivery model that matches testing demand with capacity. The National Health Laboratory Service has predominantly implemented laboratory-based CD4 testing. Coverage gaps, over-/under-capacitation and optimal placement of point-of-care (POC testing sites need investigation.Objectives: We assessed the impact of relational algebraic capacitated location (RACL algorithm outcomes on the allocation of laboratory and POC testing sites.Methods: The RACL algorithm was developed to allocate laboratories and POC sites to ensure coverage using a set coverage approach for a defined travel time (T. The algorithm was repeated for three scenarios (A: T = 4; B: T = 3; C: T = 2 hours. Drive times for a representative sample of health facility clusters were used to approximate T. Outcomes included allocation of testing sites, Euclidian distances and test volumes. Additional analysis included platform distribution and space requirement assessment. Scenarios were reported as fusion table maps.Results: Scenario A would offer a fully-centralised approach with 15 CD4 laboratories without any POC testing. A significant increase in volumes would result in a four-fold increase at busier laboratories. CD4 laboratories would increase to 41 in scenario B and 61 in scenario C. POC testing would be offered at two sites in scenario B and 20 sites in scenario C.Conclusion: The RACL algorithm provides an objective methodology to address coverage gaps through the allocation of CD4 laboratories and POC sites for a given T. The algorithm outcomes need to be assessed in the context of local conditions.

  6. Platform Constellations

    DEFF Research Database (Denmark)

    Staykova, Kalina Stefanova; Damsgaard, Jan

    2016-01-01

    This research paper presents an initial attempt to introduce and explain the emergence of new phenomenon, which we refer to as platform constellations. Functioning as highly modular systems, the platform constellations are collections of highly connected platforms which co-exist in parallel...... and as such allow us to study platforms not only as separate entities, but also to investigate the relationship between several platforms offered and governed by one and the same platform provider. By investigating two case studies of indigenous platform constellations formed around the hugely popular instant...... messaging apps KakaoTalk and LINE, we are able to gain valuable insights about the nature of these new constructions and to capture and synthesize their main characteristics in a framework. Our results show that platform constellations possess unique innovative capabilities, which can improve users...

  7. Payment Platform

    DEFF Research Database (Denmark)

    Hjelholt, Morten; Damsgaard, Jan

    2012-01-01

    Payment transactions through the use of physical coins, bank notes or credit cards have for centuries been the standard formats of exchanging money. Recently online and mobile digital payment platforms has entered the stage as contenders to this position and possibly could penetrate societies...... thoroughly and substitute current payment standards in the decades to come. This paper portrays how digital payment platforms evolve in socio-technical niches and how various technological platforms aim for institutional attention in their attempt to challenge earlier platforms and standards. The paper...... applies a co-evolutionary multilevel perspective to model the interplay and processes between technology and society wherein digital payment platforms potentially will substitute other payment platforms just like the credit card negated the check. On this basis this paper formulate a multilevel conceptual...

  8. Framework Programmable Platform for the Advanced Software Development Workstation (FPP/ASDW). Demonstration framework document. Volume 1: Concepts and activity descriptions

    Science.gov (United States)

    Mayer, Richard J.; Blinn, Thomas M.; Dewitte, Paul S.; Crump, John W.; Ackley, Keith A.

    1992-01-01

    The Framework Programmable Software Development Platform (FPP) is a project aimed at effectively combining tool and data integration mechanisms with a model of the software development process to provide an intelligent integrated software development environment. Guided by the model, this system development framework will take advantage of an integrated operating environment to automate effectively the management of the software development process so that costly mistakes during the development phase can be eliminated. The Advanced Software Development Workstation (ASDW) program is conducting research into development of advanced technologies for Computer Aided Software Engineering (CASE).

  9. [Lens platform].

    Science.gov (United States)

    Łukaszewska-Smyk, Agnieszka; Kałuzny, Józef

    2010-01-01

    The lens platform defines lens structure and lens material. Evolution of lens comprises change in their shape, angulation of haptens and transition of three-piece lens into one-piece lens. The lens fall into two categories: rigid (PMMA) and soft (siliconic, acrylic, colameric). The main lens maaterials are polymers (hydrophilic and hydrophobic). The lens platform has an effect on biocompatibility, bioadhesion, stability of lens in capsule, degree of PCO evolution and sensitiveness to laser damages.

  10. Platform contents

    OpenAIRE

    Renault, Régis

    2014-01-01

    A monopoly platform hosts advertisers who compete on a market for horizontally differentiated products. These products may be either mass market products that appeal broadly to the entire consumer population or niche products that are tailored to the tastes of some particular group. Consumers search sequentially through ads incurring a surfing cost of moving to the next ad. They may click on an ad at some cost, which provides all relevant information and the opportunity to buy. The platform c...

  11. HipMatch: an object-oriented cross-platform program for accurate determination of cup orientation using 2D-3D registration of single standard X-ray radiograph and a CT volume.

    Science.gov (United States)

    Zheng, Guoyan; Zhang, Xuan; Steppacher, Simon D; Murphy, Stephen B; Siebenrock, Klaus A; Tannast, Moritz

    2009-09-01

    The widely used procedure of evaluation of cup orientation following total hip arthroplasty using single standard anteroposterior (AP) radiograph is known inaccurate, largely due to the wide variability in individual pelvic orientation relative to X-ray plate. 2D-3D image registration methods have been introduced for an accurate determination of the post-operative cup alignment with respect to an anatomical reference extracted from the CT data. Although encouraging results have been reported, their extensive usage in clinical routine is still limited. This may be explained by their requirement of a CAD model of the prosthesis, which is often difficult to be organized from the manufacturer due to the proprietary issue, and by their requirement of either multiple radiographs or a radiograph-specific calibration, both of which are not available for most retrospective studies. To address these issues, we developed and validated an object-oriented cross-platform program called "HipMatch" where a hybrid 2D-3D registration scheme combining an iterative landmark-to-ray registration with a 2D-3D intensity-based registration was implemented to estimate a rigid transformation between a pre-operative CT volume and the post-operative X-ray radiograph for a precise estimation of cup alignment. No CAD model of the prosthesis is required. Quantitative and qualitative results evaluated on cadaveric and clinical datasets are given, which indicate the robustness and the accuracy of the program. HipMatch is written in object-oriented programming language C++ using cross-platform software Qt (TrollTech, Oslo, Norway), VTK, and Coin3D and is transportable to any platform.

  12. ITS Platform

    DEFF Research Database (Denmark)

    Tøfting, Svend; Lahrmann, Harry; Agerholm, Niels

    2014-01-01

    Aalborg University and two local companies have over the past four years developed and tested an ITS Platform, which can be used for communication with cars and for providing a number of services to the drivers. The purpose has been to perform a technological test of the possible use of a hidden ...... not have to be very intelligent. This is gradually taken over by applications on smart phones. The ITS Platform with 425 test drivers is now completely developed and can be used for technological testing of e.g. payment systems.......Aalborg University and two local companies have over the past four years developed and tested an ITS Platform, which can be used for communication with cars and for providing a number of services to the drivers. The purpose has been to perform a technological test of the possible use of a hidden...

  13. ITS Platform

    DEFF Research Database (Denmark)

    Tøfting, Svend; Lahrmann, Harry; Agerholm, Niels

    2014-01-01

    Aalborg University and two local companies have over the past four years developed and tested an ITS Platform, which can be used for communication with cars and for providing a number of services to the drivers. The purpose has been to perform a technological test of the possible use of a hidden ...... not have to be very intelligent. This is gradually taken over by applications on smart phones. The ITS Platform with 425 test drivers is now completely developed and can be used for technological testing of e.g. payment systems....

  14. Platform computing

    CERN Multimedia

    2002-01-01

    "Platform Computing releases first grid-enabled workload management solution for IBM eServer Intel and UNIX high performance computing clusters. This Out-of-the-box solution maximizes the performance and capability of applications on IBM HPC clusters" (1/2 page) .

  15. Platform Constellations

    DEFF Research Database (Denmark)

    Staykova, Kalina Stefanova; Damsgaard, Jan

    2016-01-01

    messaging apps KakaoTalk and LINE, we are able to gain valuable insights about the nature of these new constructions and to capture and synthesize their main characteristics in a framework. Our results show that platform constellations possess unique innovative capabilities, which can improve users......’ acquisition and users’ engagement rates as well as unlock new sources of value creation and diversify revenue streams....

  16. An Autonomous Platform Simulator (APS)

    Science.gov (United States)

    1989-06-01

    4 Da~c o! Rcp .’rt’ yeur. :nr.e,1 Page Count Master’s Thesi rmT Ju’ne 1 9 9 Ze 16 Supplementary Notat~on 14 The views expressed in this thesis are...the flight volume is based on the firing platform’s current LOS not the LOS at the time of firing. The near and far clipping planes are set to the

  17. Product Platform Performance

    DEFF Research Database (Denmark)

    Munk, Lone

    engaging in platform-based product development. Similarly platform assessment criteria lack empirical verification regarding relevance and sufficiency. The thesis focuses on • the process of identifying and estimating internal effects, • verification of performance of product platforms, (i...... to support this understanding. Finally a categorisation of different approaches to platform-based product development is introduced, based on the companies from the industrial study.......The aim of this research is to improve understanding of platform-based product development by studying platform performance in relation to internal effects in companies. Platform-based product development makes it possible to deliver product variety and at the same time reduce the needed resources...

  18. Product Platform Modeling

    DEFF Research Database (Denmark)

    Pedersen, Rasmus

    on the notion that reuse and encapsulation of platform elements are fundamental characteristics of a product platform. Reuse covers the desire to reuse and share certain assets across a family of products and/or across generations of products. Product design solutions and principles are often regarded...... as important assets in a product platform, yet activities, working patterns, processes and knowledge can also be reused in a platform approach. Encapsulation is seen as a process in which the different elements of a platform are grouped into well defined and self-contained units which are decoupled from each......This PhD thesis has the title Product Platform Modelling. The thesis is about product platforms and visual product platform modelling. Product platforms have gained an increasing attention in industry and academia in the past decade. The reasons are many, yet the increasing globalisation...

  19. ITS Platform North Denmark

    DEFF Research Database (Denmark)

    Lahrmann, Harry; Agerholm, Niels; Juhl, Jens

    2012-01-01

    This paper presents the project entitled “ITS Platform North Denmark” which is used as a test platform for Intelligent Transportation System (ITS) solutions. The platform consists of a newly developed GNSS/GPRS On Board Unit (OBU) to be installed in 500 cars, a backend server and a specially...... designed digital road map for ITS applications. The platform is freely accessible, which means that third party applications could be run on the platform. It is estimated that using this platform enables the ITS applications to be developed for 20% of the normal cost, hence third party are invited to test...... their applications in this platform. This paper presents the platform’s potentials and explains a series of test applications which are under development on it. Moreover, a number of new projects planned for the platform are demonstrated....

  20. Mobile platform security

    CERN Document Server

    Asokan, N; Dmitrienko, Alexandra

    2013-01-01

    Recently, mobile security has garnered considerable interest in both the research community and industry due to the popularity of smartphones. The current smartphone platforms are open systems that allow application development, also for malicious parties. To protect the mobile device, its user, and other mobile ecosystem stakeholders such as network operators, application execution is controlled by a platform security architecture. This book explores how such mobile platform security architectures work. We present a generic model for mobile platform security architectures: the model illustrat

  1. Continuous Platform Development

    DEFF Research Database (Denmark)

    Nielsen, Ole Fiil

    low risks and investments but also with relatively fuzzy results. When looking for new platform projects, it is important to make sure that the company and market is ready for the introduction of platforms, and to make sure that people from marketing and sales, product development, and downstream......, but continuous product family evolution challenges this strategy. The concept of continuous platform development is based on the fact that platform development should not be a one-time experience but rather an ongoing process of developing new platforms and updating existing ones, so that product family...

  2. Social media tools and platforms in learning environments

    CERN Document Server

    2011-01-01

    This volume covers original research work on the use of social computing and related technologies in education, including the emerging applications of Web 2.0 as an educational platform, and examines the associated privacy, risk, security, and policy issues.

  3. Cross-Platform Technologies

    Directory of Open Access Journals (Sweden)

    Maria Cristina ENACHE

    2017-04-01

    Full Text Available Cross-platform - a concept becoming increasingly used in recent years especially in the development of mobile apps, but this consistently over time and in the development of conventional desktop applications. The notion of cross-platform software (multi-platform or platform-independent refers to a software application that can run on more than one operating system or computing architecture. Thus, a cross-platform application can operate independent of software or hardware platform on which it is execute. As a generic definition presents a wide range of meanings for purposes of this paper we individualize this definition as follows: we will reduce the horizon of meaning and we use functionally following definition: a cross-platform application is a software application that can run on more than one operating system (desktop or mobile identical or in a similar way.

  4. A microfluidic AFM cantilever based dispensing and aspiration platform

    NARCIS (Netherlands)

    Van Oorschot, R.; Perez Garza, H.H.; Derks, R.J.S.; Staufer, U.; Ghatkesar, M.K.

    2015-01-01

    We present the development of a microfluidic AFM (atomic force microscope) cantilever-based platform to enable the local dispensing and aspiration of liquid with volumes in the pico-to-femtoliter range. The platform consists of a basic AFM measurement system, microfluidic AFM chip, fluidic interface

  5. Platform switching and bone platform switching.

    Science.gov (United States)

    Carinci, Francesco; Brunelli, Giorgio; Danza, Matteo

    2009-01-01

    Bone platform switching involves an inward bone ring in the coronal part of the implant that is in continuity with the alveolar bone crest. Bone platform switching is obtained by using a dental fixture with a reverse conical neck. A retrospective study was performed to evaluate the effectiveness of conventional vs reverse conical neck implants. In the period between May 2004 and November 2007, 86 patients (55 females and 31 males; median age, 53 years) were operated and 234 implants were inserted: 40 and 194 were conventional vs reverse conical neck implants, respectively. Kaplan-Meier algorithm and Cox regression were used to detect those variables associated with the clinical outcome. No differences in survival and success rates were detected between conventional vs reverse conical neck implants alone or in combination with any of the studied variables. Although bone platform switching leads to several advantages, no statistical difference in alveolar crest resorption is detected in comparison with reverse conical neck implants. We suppose that the proximity of the implant abutment junction to the alveolar crestal bone gives no protection against the microflora contained in the micrograph. Additional studies on larger series and a combination of platform switching and bone platform switching could lead to improved clinical outcomes.

  6. Platform development supportedby gaming

    DEFF Research Database (Denmark)

    Mikkola, Juliana Hsuan; Hansen, Poul H. Kyvsgård

    2007-01-01

    The challenge of implementing industrial platforms in practice can be described as a configuration problem caused by high number of variables, which often have contradictory influences on the total performance of the firm. Consequently, the specific platform decisions become extremely complex......, possibly increasing the strategic risks for the firm. This paper reports preliminary findings on platform management process at LEGO, a Danish toy company.  Specifically, we report the process of applying games combined with simulations and workshops in the platform development. We also propose a framework......, based on the portfolio management thinking, to measure the degree of modularity embedded in a given platform and to what extent it is aligned with other platforms....

  7. DFH-3 Satellite Platform

    Institute of Scientific and Technical Information of China (English)

    RenShufang

    2005-01-01

    The DFH-3 satellite platform is designed and developed by China Academy of Space Technology (CAST). It is a medium capability communications satellite platform. The platform adopts threeaxis attitude stabilization control system, having solar array output power of 1.7kW by the end of its design lifetime of 8 years. Its mass is 2100kg with payload capacity of 220kg.

  8. Product Platform Replacements

    DEFF Research Database (Denmark)

    Sköld, Martin; Karlsson, Christer

    2012-01-01

    Purpose – It is argued in this article that too little is known about product platforms and how to deal with them from a manager's point of view. Specifically, little information exists regarding when old established platforms are replaced by new generations in R&D and production environments...... originality and value is achieved by focusing on product platform replacements believed to represent a growing management challenge....

  9. The Creative Platform

    DEFF Research Database (Denmark)

    Byrge, Christian; Hansen, Søren

    This book is about introducing more creativity into general educational courses and cross-disciplinary activities. It is directed toward teachers at all levels in the educational system, but the Creative Platform is a general model, and thus the creative process will fundamentally be the same...... whether you consider thirdgrade teaching, human-resource development, or radical new thinking in product development in a company. The Creative Platform was developed at Aalborg University through a series of research-and-development activities in collaboration with educational institutions and private...... you can use in your work with the Creative Platform. This book is intended as an introduction on how to use the Creative Platform....

  10. Omnidirectional holonomic platforms

    Energy Technology Data Exchange (ETDEWEB)

    Pin, F.G.; Killough, S.M.

    1994-06-01

    This paper presents the concepts for a new family of wheeled platforms which feature full omnidirectionality with simultaneous and independently controlled rotational and translational motion capabilities. The authors first present the orthogonal-wheels concept and the two major wheel assemblies on which these platforms are based. They then describe how a combination of these assemblies with appropriate control can be used to generate an omnidirectional capability for mobile robot platforms. The design and control of two prototype platforms are then presented and their respective characteristics with respect to rotational and translational motion control are discussed.

  11. Advanced offshore oil platforms

    Energy Technology Data Exchange (ETDEWEB)

    Ellers, F.S.

    1982-04-01

    Four innovative offshore platforms that are designed to withstand 100-foot waves in waters 600-feet deep are described. These platforms are: (1) Stratfjord B Concrete Gravity-Base Platform; (2) Magnus Steel-Template-Jacket Platform; (3) Hutton Tension-Leg Platform; and (4) Block 280 Guyed Tower. The Statfjord B platform, designed in Norway, rests on four massive concrete columns with storage tanks at the base. It depends solely on its own mass for stability. The Magnus platform, designed by the British, is the heaviest offshore platform yet fabricated, weighing 41,000 tons. Two of the platform's four legs will incorporate flotation chambers so that the structure can be floated to its site in the North Sea. The Hutton structure, also designed in England, will consist of a buoyant hull tethered to the sea floor by slender steel tubes at its four corners. The first platform of its type, the Hutton structure is also destined for the North Sea. The US designed Block 280 guyed tower is designed for service in the Gulf of Mexico in water 1000 feet deep. It will be pinned to the sea floor by a spokelike array of 20 steel cables, each one more than 3000 feet long. The tower and its guys will weigh 43,000 tons, slightly more than the Magnus steel-template jacket and more than four time as much as the Eiffel Tower. At a cost of approximately $2.6 billion, the Magnus is the most expensive offshore platform to date. The Statfjord B was put into production in 1982. The Magnus is scheduled for oil production in 1983. The Hutton and the Block 280 will both be producing in 1984. (JMT)

  12. EURESCOM Services Platform

    NARCIS (Netherlands)

    Nieuwenhuis, Lambertus Johannes Maria; van Halteren, Aart

    1999-01-01

    This paper presents the results of the EURESCOM Project 715. In February 1999, a large team of researchers from six European public network operators completed a two year period of cooperative experiments on a TINA-based environment, called the EURESCOM Services Platform (ESP). This platform

  13. Siberian Platform: Geology and Natural Bitumen Resources

    Science.gov (United States)

    Meyer, Richard F.; Freeman, P.A.

    2006-01-01

    Summary: The Siberian platform is located between the Yenisey River on the west and the Lena River on the south and east. The Siberian platform is vast in size and inhospitable in its climate. This report is concerned principally with the setting, formation, and potential volumes of natural bitumen. In this report the volumes of maltha and asphalt referred to in the Russian literature are combined to represent natural bitumen. The generation of hydrocarbons and formation of hydrocarbon accumulations are discussed. The sedimentary basins of the Platform are described in terms of the Klemme basin classification system and the conditions controlling formation of natural bitumen. Estimates of in-place bitumen resources are reviewed and evaluated. If the bitumen volume estimate is confined to parts of identified deposits where field observations have verified rock and bitumen grades values, the bitumen resource amounts to about 62 billion barrels of oil in-place. However, estimates of an order of magnitude larger can be obtained if additional speculative and unverified rock volumes and grade measures are included.

  14. The Common HOL Platform

    OpenAIRE

    Adams, Mark

    2015-01-01

    The Common HOL project aims to facilitate porting source code and proofs between members of the HOL family of theorem provers. At the heart of the project is the Common HOL Platform, which defines a standard HOL theory and API that aims to be compatible with all HOL systems. So far, HOL Light and hol90 have been adapted for conformance, and HOL Zero was originally developed to conform. In this paper we provide motivation for a platform, give an overview of the Common HOL Platform's theory and...

  15. Ladder attachment platform

    Science.gov (United States)

    Swygert,; Richard, W [Springfield, SC

    2012-08-28

    A ladder attachment platform is provided that includes a base for attachment to a ladder that has first and second side rails and a plurality of rungs that extend between in a lateral direction. Also included is a user platform for having a user stand thereon that is carried by the base. The user platform may be positioned with respect to the ladder so that it is not located between a first plane that extends through the first side rail and is perpendicular to the lateral direction and a second plane that extends through the second side rail and is perpendicular to the lateral direction.

  16. Platform-based production development

    DEFF Research Database (Denmark)

    Bossen, Jacob; Brunoe, Thomas Ditlev; Nielsen, Kjeld

    2015-01-01

    Platforms as a means for applying modular thinking in product development is relatively well studied, but platforms in the production system has until now not been given much attention. With the emerging concept of platform-based co-development the importance of production platforms is though...... indisputable. This paper presents state-of-the-art literature on platform research related to production platforms and investigates gaps in the literature. The paper concludes on findings by proposing future research directions....

  17. 张柏芝Wanna be HappY

    Institute of Scientific and Technical Information of China (English)

    1999-01-01

    98年中,刚从澳洲高中毕业回港的张柏芝的经理人朱永龙的安排下,接拍了《阳光柠檬荼》的广告,当这3个不同版本的广告片播出后,各大小杂志、电影公司及广告公司均纷纷联络其经理人朱永龙。其中周星驰的99年贺岁片《喜剧之王》铁定张柏芝为女主角。此片最后更成为同期贺岁片中的总冠军,票房成绩达三千万。而紧接着,张柏芝接拍了由嘉禾电影公司出品,马楚成执导的爱情文艺新片《星愿》并担演女主角,与任贤齐及苏永康合力演出,此片预计在暑假黄

  18. USA Hire Testing Platform

    Data.gov (United States)

    Office of Personnel Management — The USA Hire Testing Platform delivers tests used in hiring for positions in the Federal Government. To safeguard the integrity of the hiring processes and ensure...

  19. MULTIFUNCTIONAL PLATFORMS AND

    African Journals Online (AJOL)

    Solar service centres and multifunctional platforms are innovative concepts for providing energy services in ... same time generate income. obeng ..... communities the driving force behind the ... operator(s) had to contact repairers outside their.

  20. The Common HOL Platform

    Directory of Open Access Journals (Sweden)

    Mark Adams

    2015-07-01

    Full Text Available The Common HOL project aims to facilitate porting source code and proofs between members of the HOL family of theorem provers. At the heart of the project is the Common HOL Platform, which defines a standard HOL theory and API that aims to be compatible with all HOL systems. So far, HOL Light and hol90 have been adapted for conformance, and HOL Zero was originally developed to conform. In this paper we provide motivation for a platform, give an overview of the Common HOL Platform's theory and API components, and show how to adapt legacy systems. We also report on the platform's successful application in the hand-translation of a few thousand lines of source code from HOL Light to HOL Zero.

  1. The Creative Platform

    DEFF Research Database (Denmark)

    Byrge, Christian; Hansen, Søren

    whether you consider thirdgrade teaching, human-resource development, or radical new thinking in product development in a company. The Creative Platform was developed at Aalborg University through a series of research-and-development activities in collaboration with educational institutions and private......This book is about introducing more creativity into general educational courses and cross-disciplinary activities. It is directed toward teachers at all levels in the educational system, but the Creative Platform is a general model, and thus the creative process will fundamentally be the same...... companies. It is a project in which the goal is to make a hands-on approach to a knowledge perspective on enhancing creativity. The underlying ambition of the Creative Platform is to make it easier to promote creativity. At www.uka.aau.dk/The+Creative+Platform, you can find extra materials and instructions...

  2. National Community Solar Platform

    Energy Technology Data Exchange (ETDEWEB)

    Rupert, Bart [Clean Energy Collective, Louisville, CO (United States)

    2016-06-30

    This project was created to provide a National Community Solar Platform (NCSP) portal known as Community Solar Hub, that is available to any entity or individual who wants to develop community solar. This has been done by providing a comprehensive portal to make CEC’s solutions, and other proven community solar solutions, externally available for everyone to access – making the process easy through proven platforms to protect subscribers, developers and utilities. The successful completion of this project provides these tools via a web platform and integration APIs, a wide spectrum of community solar projects included in the platform, multiple groups of customers (utilities, EPCs, and advocates) using the platform to develop community solar, and open access to anyone interested in community solar. CEC’s Incubator project includes web-based informational resources, integrated systems for project information and billing systems, and engagement with customers and users by community solar experts. The combined effort externalizes much of Clean Energy Collective’s industry-leading expertise, allowing third parties to develop community solar without duplicating expensive start-up efforts. The availability of this platform creates community solar projects that are cheaper to build and cheaper to participate in, furthering the goals of DOE’s SunShot Initiative. Final SF 425 Final SF 428 Final DOE F 2050.11 Final Report Narrative

  3. HARNESSING BIG DATA VOLUMES

    Directory of Open Access Journals (Sweden)

    Bogdan DINU

    2014-04-01

    Full Text Available Big Data can revolutionize humanity. Hidden within the huge amounts and variety of the data we are creating we may find information, facts, social insights and benchmarks that were once virtually impossible to find or were simply inexistent. Large volumes of data allow organizations to tap in real time the full potential of all the internal or external information they possess. Big data calls for quick decisions and innovative ways to assist customers and the society as a whole. Big data platforms and product portfolio will help customers harness to the full the value of big data volumes. This paper deals with technical and technological issues related to handling big data volumes in the Big Data environment.

  4. The Platformization of the Web: Making Web Data Platform Ready

    NARCIS (Netherlands)

    A. Helmond

    2015-01-01

    In this article, I inquire into Facebook’s development as a platform by situating it within the transformation of social network sites into social media platforms. I explore this shift with a historical perspective on, what I refer to as, platformization, or the rise of the platform as the dominant

  5. Platform Performance and Challenges - using Platforms in Lego Company

    DEFF Research Database (Denmark)

    Munk, Lone; Mortensen, Niels Henrik

    2009-01-01

    by the product defining users (product developers) and platform erosion. When the platforms are not used it is due to: unsuitable calculation models, lack of goals, rewards or benefits from management, unattractive tradeoffs and difficulties in understanding the platform. This indicates that platform design...... needs focus on the incentive of using the platform. This problem lacks attention in literature, as well as industry, where assessment criteria do not cover this aspect. Therefore, we recommend including user incentive in platform assessment criteria to these challenges. Concrete solution elements...... ensuring user incentive in platforms is an object for future research...

  6. Volume Entropy

    CERN Document Server

    Astuti, Valerio; Rovelli, Carlo

    2016-01-01

    Building on a technical result by Brunnemann and Rideout on the spectrum of the Volume operator in Loop Quantum Gravity, we show that the dimension of the space of the quadrivalent states --with finite-volume individual nodes-- describing a region with total volume smaller than $V$, has \\emph{finite} dimension, bounded by $V \\log V$. This allows us to introduce the notion of "volume entropy": the von Neumann entropy associated to the measurement of volume.

  7. Transactional Network Platform: Applications

    Energy Technology Data Exchange (ETDEWEB)

    Katipamula, Srinivas; Lutes, Robert G.; Ngo, Hung; Underhill, Ronald M.

    2013-10-31

    In FY13, Pacific Northwest National Laboratory (PNNL) with funding from the Department of Energy’s (DOE’s) Building Technologies Office (BTO) designed, prototyped and tested a transactional network platform to support energy, operational and financial transactions between any networked entities (equipment, organizations, buildings, grid, etc.). Initially, in FY13, the concept demonstrated transactions between packaged rooftop air conditioners and heat pump units (RTUs) and the electric grid using applications or "agents" that reside on the platform, on the equipment, on a local building controller or in the Cloud. The transactional network project is a multi-lab effort with Oakridge National Laboratory (ORNL) and Lawrence Berkeley National Laboratory (LBNL) also contributing to the effort. PNNL coordinated the project and also was responsible for the development of the transactional network (TN) platform and three different applications associated with RTUs. This document describes two applications or "agents" in details, and also summarizes the platform. The TN platform details are described in another companion document.

  8. Vertical Wave Impacts on Offshore Wind Turbine Inspection Platforms

    OpenAIRE

    Bredmose, Henrik; Jacobsen, Niels Gjøl

    2011-01-01

    Breaking wave impacts on a monopile at 20 m depth are computed with a VOF (Volume Of Fluid) method. The impacting waves are generated by the second-order focused wave group technique, to obtain waves that break at the position of the monopile. The subsequent impact from the vertical run-up flow on a horizontal inspection platform is computed for five different platform levels. The computational results show details of monopile impact such as slamming pressures from the overturning wave front ...

  9. Identification of platform levels

    DEFF Research Database (Denmark)

    Mortensen, Niels Henrik

    2005-01-01

    reduction, ability to launch a wider product portfolio without increasing resources and reduction of complexity within the whole company. To support the multiple product development process, platform based product development has in many companies such as Philips, VW, Ford etc. proven to be a very effective...... because the nature of developing platforms and applications are very different. In single product development reuse is often determined by individual designers, in multiple product development reuse is to a large degree a management issue. It is difficult for a company to switch from single to multiple...... development will be examined. Based on the identification of the above characteristics five platform levels are described. The research presented in this paper is a result of MSc, Ph.D projects at the Technical University of Denmark and consultancy projects within the organisation of Institute of Product...

  10. Universal visualization platform

    Science.gov (United States)

    Gee, Alexander G.; Li, Hongli; Yu, Min; Smrtic, Mary Beth; Cvek, Urska; Goodell, Howie; Gupta, Vivek; Lawrence, Christine; Zhou, Jainping; Chiang, Chih-Hung; Grinstein, Georges G.

    2005-03-01

    Although there are a number of visualization systems to choose from when analyzing data, only a few of these allow for the integration of other visualization and analysis techniques. There are even fewer visualization toolkits and frameworks from which one can develop ones own visualization applications. Even within the research community, scientists either use what they can from the available tools or start from scratch to define a program in which they are able to develop new or modified visualization techniques and analysis algorithms. Presented here is a new general-purpose platform for constructing numerous visualization and analysis applications. The focus of this system is the design and experimentation of new techniques, and where the sharing of and integration with other tools becomes second nature. Moreover, this platform supports multiple large data sets, and the recording and visualizing of user sessions. Here we introduce the Universal Visualization Platform (UVP) as a modern data visualization and analysis system.

  11. Geostationary multipurpose platforms

    Science.gov (United States)

    Bekey, I.; Bowman, R. M.

    1981-01-01

    In addition to the advantages generally associated with orbital platforms, such as improved reliability, economies of scale, simple connectivity of elements, reduced tracking demands and the restraint of orbital object population growth, geostationary platforms yield: (1) continuous access by fixed ground antennas for communications services; (2) continuous monitoring of phenomena over chosen regions of the earth's surface; (3) a preferred location for many solar-terrestrial physics experiments. The geostationary platform also offers a low-risk and economical solution to the impending saturation of the orbital arc/frequency spectrum, maximizing the capacity of individual slots and increasing the utility of the entire arc. It also allows the use of many small, simple and inexpensive earth stations through complexity inversion and high power per beam. Block diagram and operational flowcharts are provided.

  12. Platforms for antibiotic discovery.

    Science.gov (United States)

    Lewis, Kim

    2013-05-01

    The spread of resistant bacteria, leading to untreatable infections, is a major public health threat but the pace of antibiotic discovery to combat these pathogens has slowed down. Most antibiotics were originally isolated by screening soil-derived actinomycetes during the golden era of antibiotic discovery in the 1940s to 1960s. However, diminishing returns from this discovery platform led to its collapse, and efforts to create a new platform based on target-focused screening of large libraries of synthetic compounds failed, in part owing to the lack of penetration of such compounds through the bacterial envelope. This article considers strategies to re-establish viable platforms for antibiotic discovery. These include investigating untapped natural product sources such as uncultured bacteria, establishing rules of compound penetration to enable the development of synthetic antibiotics, developing species-specific antibiotics and identifying prodrugs that have the potential to eradicate dormant persisters, which are often responsible for hard-to-treat infections.

  13. Windows Azure Platform

    CERN Document Server

    Redkar, Tejaswi

    2011-01-01

    The Windows Azure Platform has rapidly established itself as one of the most sophisticated cloud computing platforms available. With Microsoft working to continually update their product and keep it at the cutting edge, the future looks bright - if you have the skills to harness it. In particular, new features such as remote desktop access, dynamic content caching and secure content delivery using SSL make the latest version of Azure a more powerful solution than ever before. It's widely agreed that cloud computing has produced a paradigm shift in traditional architectural concepts by providin

  14. Windows Azure Platform

    CERN Document Server

    Redkar, Tejaswi

    2010-01-01

    The Azure Services Platform is a brand-new cloud-computing technology from Microsoft. It is composed of four core components-Windows Azure, .NET Services, SQL Services, and Live Services-each with a unique role in the functioning of your cloud service. It is the goal of this book to show you how to use these components, both separately and together, to build flawless cloud services. At its heart Windows Azure Platform is a down-to-earth, code-centric book. This book aims to show you precisely how the components are employed and to demonstrate the techniques and best practices you need to know

  15. Wireless sensor platform

    Energy Technology Data Exchange (ETDEWEB)

    Joshi, Pooran C.; Killough, Stephen M.; Kuruganti, Phani Teja

    2017-08-08

    A wireless sensor platform and methods of manufacture are provided. The platform involves providing a plurality of wireless sensors, where each of the sensors is fabricated on flexible substrates using printing techniques and low temperature curing. Each of the sensors can include planar sensor elements and planar antennas defined using the printing and curing. Further, each of the sensors can include a communications system configured to encode the data from the sensors into a spread spectrum code sequence that is transmitted to a central computer(s) for use in monitoring an area associated with the sensors.

  16. Mobile4D platform

    CSIR Research Space (South Africa)

    Botha, Adèle

    2010-05-01

    Full Text Available . It is a communication platform that has architecture for creating, deploying and managing services and applications by integrating voice, video and data across a range of IP and telecom communication networks. In 2007, Red Hat made a firm commitment... based on the Mobicents muni ations Platform brand. 2.1.5  Telco specific User‐Generated Services   A variety of communication network operators have started initiatives to address User- Generated Services for the Telecom domain. Some...

  17. German crowd-investing platforms: Literature review and survey

    Directory of Open Access Journals (Sweden)

    David Grundy

    2016-12-01

    Full Text Available This article presents a comprehensive overview of the current German crowd-investing market drawing on a data-set of 31 crowd-investing platforms including the analysis of 265 completed projects. While crowd-investing market still only represents a niche in the German venture capital market, there is potential for an increase in both market volume and in average project investment. The market share is distributed among a few crowd-investing platforms with high entry barriers for new platforms although platforms that specialise in certain sectors have managed to successfully enter the market. German crowd-investing platforms are found to promote mainly internet-based enterprises (36% followed by projects in real estate (24% and green projects (19%, with the median money raised 100,000 euro.

  18. Games and Platform Decisions

    DEFF Research Database (Denmark)

    Hansen, Poul H. Kyvsgård; Mikkola, Juliana Hsuan

    2007-01-01

    is the application of on-line games in order to provide training for decision makers and in order to generate overview over the implications of platform decisions. However, games have to be placed in a context with other methods and we argue that a mixture of games, workshops, and simulations can provide improved...

  19. Creative Platform Learning (CPL)

    DEFF Research Database (Denmark)

    Christensen, Jonna Langeland; Hansen, Søren

    Creative Platform Learning (CPL) er en pædagogisk metode, der skaber foretagsomme og innovative elever, der kan anvende deres kreativitet til at lære nyt. Ifølge den nye skolereform skal Innovation og entreprenørskab tydeliggøres i alle fag. I CPL er det en integreret del af undervisningen...

  20. Games and Platform Decisions

    DEFF Research Database (Denmark)

    Hansen, Poul H. Kyvsgård; Mikkola, Juliana Hsuan

    2007-01-01

    is the application of on-line games in order to provide training for decision makers and in order to generate overview over the implications of platform decisions. However, games have to be placed in a context with other methods and we argue that a mixture of games, workshops, and simulations can provide improved...

  1. Predicting Droplet Formation on Centrifugal Microfluidic Platforms

    Science.gov (United States)

    Moebius, Jacob Alfred

    Centrifugal microfluidics is a widely known research tool for biological sample and water quality analysis. Currently, the standard equipment used for such diagnostic applications include slow, bulky machines controlled by multiple operators. These machines can be condensed into a smaller, faster benchtop sample-to-answer system. Sample processing is an important step taken to extract, isolate, and convert biological factors, such as nucleic acids or proteins, from a raw sample to an analyzable solution. Volume definition is one such step. The focus of this thesis is the development of a model predicting monodispersed droplet formation and the application of droplets as a technique for volume definition. First, a background of droplet microfluidic platforms is presented, along with current biological analysis technologies and the advantages of integrating such technologies onto microfluidic platforms. Second, background and theories of centrifugal microfluidics is given, followed by theories relevant to droplet emulsions. Third, fabrication techniques for centrifugal microfluidic designs are discussed. Finally, the development of a model for predicting droplet formation on the centrifugal microfluidic platform are presented for the rest of the thesis. Predicting droplet formation analytically based on the volumetric flow rates of the continuous and dispersed phases, the ratios of these two flow rates, and the interfacial tension between the continuous and dispersed phases presented many challenges, which will be discussed in this work. Experimental validation was completed using continuous phase solutions of different interfacial tensions. To conclude, prospective applications are discussed with expected challenges.

  2. Mobile Platforms and Development Environments

    CERN Document Server

    Helal, Sumi; Li, Wengdong

    2012-01-01

    Mobile platform development has lately become a technological war zone with extremely dynamic and fluid movement, especially in the smart phone and tablet market space. This Synthesis lecture is a guide to the latest developments of the key mobile platforms that are shaping the mobile platform industry. The book covers the three currently dominant native platforms -- iOS, Android and Windows Phone -- along with the device-agnostic HTML5 mobile web platform. The lecture also covers location-based services (LBS) which can be considered as a platform in its own right. The lecture utilizes a sampl

  3. Online stock trading platform

    Directory of Open Access Journals (Sweden)

    Ion LUNGU

    2006-01-01

    Full Text Available The Internet is the perfect tool that can assure the market’s transparency for any user who wants to trade on the stock market. The investor can have access to the market news, financial calendar or the press releases of the issuers. A good online trading platform also provides real-time intraday quotes, trading history and technical analysis giving the investor a clearer view of the supply and demand in the market. All this information provides the investor a good image of the market and encourages him to trade. This paper wishes to draft the pieces of an online trading platform and to analyze the impact of developing and implementing one in a brokerage firm.

  4. Available: motorised platform

    CERN Document Server

    The COMPASS collaboration

    2014-01-01

    The COMPASS collaboration would like to offer to a new owner the following useful and fully operational piece of equipment, which is due to be replaced with better adapted equipment.   Please contact Erwin Bielert (erwin.bielert@cern.ch or 160539) for further information.  Motorized platform (FOR FREE):   Fabricated by ACL (Alfredo Cardoso & Cia Ltd) in Portugal. The model number is MeXs 5-­‐30.  Specifications: 5 m wide, 1 m deep, adjustable height (1.5 m if folded). Maximum working floor height: 4 m. conforms to CERN regulations, number LV158. Type LD500, capacity 500 kg and weight 2000 kg.  If no interested party is found before December 2014, the platform will be thrown away.

  5. Common tester platform concept.

    Energy Technology Data Exchange (ETDEWEB)

    Hurst, Michael James

    2008-05-01

    This report summarizes the results of a case study on the doctrine of a common tester platform, a concept of a standardized platform that can be applicable across the broad spectrum of testing requirements throughout the various stages of a weapons program, as well as across the various weapons programs. The common tester concept strives to define an affordable, next-generation design that will meet testing requirements with the flexibility to grow and expand; supporting the initial development stages of a weapons program through to the final production and surveillance stages. This report discusses a concept investing key leveraging technologies and operational concepts combined with prototype tester-development experiences and practical lessons learned gleaned from past weapons programs.

  6. OGC Collaborative Platform undercover

    Science.gov (United States)

    Buehler, G.; Arctur, D. K.; Bermudez, L. E.

    2012-12-01

    The mission of the Open Geospatial Consortium (OGC) is to serve as a global forum for the collaboration of developers and users of spatial data products and services, and to advance the development of international standards for geospatial interoperability. The OGC coordinates with over 400 institutions in the development of geospatial standards. OGC has a dedicated staff supported by a Collaborative Web Platform to enable sophisticated and successful coordination among its members. Since its origins in the early 1990s, the OGC Collaborative Web Platform has evolved organically to be the collaboration hub for standards development in the exchange of geospatial and related types of information, among a global network of thousands of technical, scientific and management professionals spanning numerous disparate application domains. This presentation describes the structure of this collaboration hub, the relationships enabled (both among and beyond OGC members), and how this network fits in a broader ecosystem of technology development and information standards organizations.

  7. Video analysis platform

    OpenAIRE

    FLORES, Pablo; Arias, Pablo; Lecumberry, Federico; Pardo, Álvaro

    2006-01-01

    In this article we present the Video Analysis Platform (VAP) which is an open source software framework for video analysis, processing and description. The main goals of VAP are: to provide a multiplatform system which allows the easy implementation of video algorithms, provide structures and algorithms for the segmentation of video data in its different levels of abstraction: shots, frames, objects, regions, etc, permit the generation and comparison of MPEG7-like descriptors, and develop tes...

  8. Cloud Robotics Platforms

    Directory of Open Access Journals (Sweden)

    Busra Koken

    2015-01-01

    Full Text Available Cloud robotics is a rapidly evolving field that allows robots to offload computation-intensive and storage-intensive jobs into the cloud. Robots are limited in terms of computational capacity, memory and storage. Cloud provides unlimited computation power, memory, storage and especially collaboration opportunity. Cloud-enabled robots are divided into two categories as standalone and networked robots. This article surveys cloud robotic platforms, standalone and networked robotic works such as grasping, simultaneous localization and mapping (SLAM and monitoring.

  9. HPC - Platforms Penta Chart

    Energy Technology Data Exchange (ETDEWEB)

    Trujillo, Angelina Michelle [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-10-08

    Strategy, Planning, Acquiring- very large scale computing platforms come and go and planning for immensely scalable machines often precedes actual procurement by 3 years. Procurement can be another year or more. Integration- After Acquisition, machines must be integrated into the computing environments at LANL. Connection to scalable storage via large scale storage networking, assuring correct and secure operations. Management and Utilization – Ongoing operations, maintenance, and trouble shooting of the hardware and systems software at massive scale is required.

  10. IP Rights and Technological Platforms

    OpenAIRE

    Robert P. Merges

    2008-01-01

    This paper is about intellectual property rights (IPRs) and platform technologies. After a brief introduction explaining some basics of networks, standards and platforms, I turn to three policy issues. The first is the role of IP in what might be termed platform policies, the decisions by courts and regulators concerning whether and how to promote multi-party access to important digital platforms such as media player hardware, cell phones, PCs, and the like. I argue that for the most part the...

  11. "Platform switching": Serendipity

    Directory of Open Access Journals (Sweden)

    N Kalavathy

    2014-01-01

    Full Text Available Implant dentistry is the latest developing field in terms of clinical techniques, research, material science and oral rehabilitation. Extensive work is being done to improve the designing of implants in order to achieve better esthetics and function. The main drawback with respect to implant restoration is achieving good osseointegration along with satisfactory stress distribution, which in turn will improve the prognosis of implant prosthesis by reducing the crestal bone loss. Many concepts have been developed with reference to surface coating of implants, surgical techniques for implant placement, immediate and delayed loading, platform switching concept, etc. This article has made an attempt to review the concept of platform switching was in fact revealed accidentally due to the nonavailability of the abutment appropriate to the size of the implant placed. A few aspect of platform switching, an upcoming idea to reduce crestal bone loss have been covered. The various methods used for locating and preparing the data were done through textbooks, Google search and related articles.

  12. "Platform switching": serendipity.

    Science.gov (United States)

    Kalavathy, N; Sridevi, J; Gehlot, Roshni; Kumar, Santosh

    2014-01-01

    Implant dentistry is the latest developing field in terms of clinical techniques, research, material science and oral rehabilitation. Extensive work is being done to improve the designing of implants in order to achieve better esthetics and function. The main drawback with respect to implant restoration is achieving good osseointegration along with satisfactory stress distribution, which in turn will improve the prognosis of implant prosthesis by reducing the crestal bone loss. Many concepts have been developed with reference to surface coating of implants, surgical techniques for implant placement, immediate and delayed loading, platform switching concept, etc. This article has made an attempt to review the concept of platform switching was in fact revealed accidentally due to the nonavailability of the abutment appropriate to the size of the implant placed. A few aspect of platform switching, an upcoming idea to reduce crestal bone loss have been covered. The various methods used for locating and preparing the data were done through textbooks, Google search and related articles.

  13. The Prodiguer Messaging Platform

    Science.gov (United States)

    Denvil, S.; Greenslade, M. A.; Carenton, N.; Levavasseur, G.; Raciazek, J.

    2015-12-01

    CONVERGENCE is a French multi-partner national project designed to gather HPC and informatics expertise to innovate in the context of running French global climate models with differing grids and at differing resolutions. Efficient and reliable execution of these models and the management and dissemination of model output are some of the complexities that CONVERGENCE aims to resolve.At any one moment in time, researchers affiliated with the Institut Pierre Simon Laplace (IPSL) climate modeling group, are running hundreds of global climate simulations. These simulations execute upon a heterogeneous set of French High Performance Computing (HPC) environments. The IPSL's simulation execution runtime libIGCM (library for IPSL Global Climate Modeling group) has recently been enhanced so as to support hitherto impossible realtime use cases such as simulation monitoring, data publication, metrics collection, simulation control, visualizations … etc. At the core of this enhancement is Prodiguer: an AMQP (Advanced Message Queue Protocol) based event driven asynchronous distributed messaging platform. libIGCM now dispatches copious amounts of information, in the form of messages, to the platform for remote processing by Prodiguer software agents at IPSL servers in Paris. Such processing takes several forms: Persisting message content to database(s); Launching rollback jobs upon simulation failure; Notifying downstream applications; Automation of visualization pipelines; We will describe and/or demonstrate the platform's: Technical implementation; Inherent ease of scalability; Inherent adaptiveness in respect to supervising simulations; Web portal receiving simulation notifications in realtime.

  14. Platform computing powers enterprise grid

    CERN Multimedia

    2002-01-01

    Platform Computing, today announced that the Stanford Linear Accelerator Center is using Platform LSF 5, to carry out groundbreaking research into the origins of the universe. Platform LSF 5 will deliver the mammoth computing power that SLAC's Linear Accelerator needs to process the data associated with intense high-energy physics research (1 page).

  15. Research on the positioning problem in HIFU surgery platform application

    Institute of Scientific and Technical Information of China (English)

    XIANG Lin-qing; GAO Xue-guan; XU Jian-bo; MA Pei-sun

    2006-01-01

    For describing the positioning process of High Intensity Focused Ultrasound (HIFU) Surgery Platform in the application in tumor treatment, a simplified representation of the shape and location of the positioning target tumor in the workspace of the platform by the Positioning Volume Ellipsoid is designed; and the Nearest Neighbor Search method is used to find the closest center point of the simplified ellipsoid tumor model in a selected patient body surface point set determined by the motion parameter of the platform. By the query result the goal positioning path configuration and an intermediate positioning path configuration for the positioning motion are determined for the positioning motion planning. Three new criterions using distance change between Positioning Volume Ellipsoid and the Ultrasound Focus Ellipsoid are proposed to evaluate the result of the whole positioning procedure.

  16. The Geohazards Exploitation Platform

    Science.gov (United States)

    Laur, Henri; Casu, Francesco; Bally, Philippe; Caumont, Hervé; Pinto, Salvatore

    2016-04-01

    The Geohazards Exploitation Platform, or Geohazards TEP (GEP), is an ESA originated R&D activity of the EO ground segment to demonstrate the benefit of new technologies for large scale processing of EO data. This encompasses on-demand processing for specific user needs, systematic processing to address common information needs of the geohazards community, and integration of newly developed processors for scientists and other expert users. The platform supports the geohazards community's objectives as defined in the context of the International Forum on Satellite EO and Geohazards organised by ESA and GEO in Santorini in 2012. The GEP is a follow on to the Supersites Exploitation Platform (SSEP) an ESA initiative to support the Geohazards Supersites & Natural Laboratories initiative (GSNL). Today the GEP allows to exploit 70+ Terabyte of ERS and ENVISAT archive and the Copernicus Sentinel-1 data available on line. The platform has already engaged 22 European early adopters in a validation activity initiated in March 2015. Since September, this validation has reached 29 single user projects. Each project is concerned with either integrating an application, running on demand processing or systematically generating a product collection using an application available in the platform. The users primarily include 15 geoscience centres and universities based in Europe: British Geological Survey (UK), University of Leeds (UK), University College London (UK), ETH University of Zurich (CH), INGV (IT), CNR-IREA and CNR-IRPI (IT), University of L'Aquila (IT), NOA (GR), Univ. Blaise Pascal & CNRS (FR), Ecole Normale Supérieure (FR), ISTERRE / University of Grenoble-Alpes (FR). In addition, there are users from Africa and North America with the University of Rabat (MA) and the University of Miami (US). Furthermore two space agencies and four private companies are involved: the German Space Research Centre DLR (DE), the European Space Agency (ESA), Altamira Information (ES

  17. Identification of platform levels

    DEFF Research Database (Denmark)

    Mortensen, Niels Henrik

    2005-01-01

    reduction, ability to launch a wider product portfolio without increasing resources and reduction of complexity within the whole company. To support the multiple product development process, platform based product development has in many companies such as Philips, VW, Ford etc. proven to be a very effective...... and efficient tool. Transforming product development from single to multiple product development is a significant change in product development often involving major changes of product models, procedures and organization. In the area of product models a set of new models has to be introduced, e.g. models...

  18. Cots Correlator Platform

    Science.gov (United States)

    Schaaf, Kjeld; Overeem, Ruud

    2004-06-01

    Moore’s law is best exploited by using consumer market hardware. In particular, the gaming industry pushes the limit of processor performance thus reducing the cost per raw flop even faster than Moore’s law predicts. Next to the cost benefits of Common-Of-The-Shelf (COTS) processing resources, there is a rapidly growing experience pool in cluster based processing. The typical Beowulf cluster of PC’s supercomputers are well known. Multiple examples exists of specialised cluster computers based on more advanced server nodes or even gaming stations. All these cluster machines build upon the same knowledge about cluster software management, scheduling, middleware libraries and mathematical libraries. In this study, we have integrated COTS processing resources and cluster nodes into a very high performance processing platform suitable for streaming data applications, in particular to implement a correlator. The required processing power for the correlator in modern radio telescopes is in the range of the larger supercomputers, which motivates the usage of supercomputer technology. Raw processing power is provided by graphical processors and is combined with an Infiniband host bus adapter with integrated data stream handling logic. With this processing platform a scalable correlator can be built with continuously growing processing power at consumer market prices.

  19. Platform Chemicals from an Oilseed Biorefinery

    Energy Technology Data Exchange (ETDEWEB)

    Tupy, Mike; Schrodi Yann

    2006-11-06

    The US chemical industry is $460 billion in size where a $150 billion segment of which is non-oxygenated chemicals that is sourced today via petroleum but is addressable by a renewable feedstock if one considers a more chemically reduced feedstock such as vegetable oils. Vegetable oil, due to its chemical functionality, provides a largely untapped opportunity as a renewable chemical source to replace petroleum-derived chemicals and produce platform chemicals unavailable today. This project examined the fertile intersection between the rich building blocks provided by vegetable oils and the enhanced chemical modification capability provided by metathesis chemistry. The technology advanced in this study is the process of ethylene cross-metathesis (referred to as ethenolysis) with vegetable oil and vegetable oil derivatives to manufacture the platform-chemical 9-decenoic acid (or 9DA) and olefin co-products. The project team meet its goals of demonstrating improved catalyst efficiencies of several multiples, deepening the mechanistic understanding of metathesis, synthesis and screening of dozens of new catalysts, designing and modeling commercial processes, and estimating production costs. One demonstrable result of the study was a step change improvement in catalyst turnover number in the ethenolysis of methyl oleate as reported here. We met our key measurable of producing 100 lbs of 9DA at the pilot-scale, which demonstrated ability to scale-up ethenolysis. DOE Project funding had significant positive impact on development of metathetically modified vegetable oils more broadly as the Cargill/Materia partnership, that was able to initiate primarily due to DOE funding, has succeeded in commercializing products, validating metathesis as a platform technology, and expanding a diverse products portfolio in high value and in large volume markets. Opportunities have expanded and business development has gained considerable momentum and enabled further expansion of the

  20. Communications payloads for geostationary platforms

    Science.gov (United States)

    Fordyce, S. W.

    1978-01-01

    Trends in communication satellites show increasing reuse of the frequency spectrum through multiple spot beams and orthogonal polarization, as well as consortia operation. Current reliance on orbital arc separation for frequency reuse may be inadequate for the projected traffic growth and the orbital slotting proposals before the ITU. This paper notes that cost advantages can accrue through common use of spacecraft subsystems and multiple users' platforms aboard a common geostationary platform. The rationale for such platforms is described and potential payloads are suggested.

  1. Utilizing platforms in industrialized construction

    DEFF Research Database (Denmark)

    Bonev, Martin; Wörösch, Michael; Hvam, Lars

    2015-01-01

    construction companies. A promising approach adapted by operations management and design theory regards individual building projects as the adjustment and recombination of components and processes from a set of predefined platforms, while configuration systems assure feasible building solutions. Design...... methods map structural platform characteristics so as to balance commonality and distinctiveness. Originality/value – This paper proposes a general theory of platform-based development and execution in the industrialised construction sector, which goes beyond concurrent approaches of standardising...

  2. Web Platform Application

    Energy Technology Data Exchange (ETDEWEB)

    Paulsworth, Ashley [Sunvestment Group, Frederick, MD (United States); Kurtz, Jim [Sunvestment Group, Frederick, MD (United States); Brun de Pontet, Stephanie [Sunvestment Group, Frederick, MD (United States)

    2016-06-15

    Sunvestment Energy Group (previously called Sunvestment Group) was established to create a web application that brings together site hosts, those who will obtain the energy from the solar array, with project developers and funders, including affinity investors. Sunvestment Energy Group (SEG) uses a community-based model that engages with investors who have some affinity with the site host organization. In addition to a financial return, these investors receive non-financial value from their investments and are therefore willing to offer lower cost capital. This enables the site host to enjoy more savings from solar through these less expensive Community Power Purchase Agreements (CPPAs). The purpose of this award was to develop an online platform to bring site hosts and investors together virtually.

  3. Energy Tracking Software Platform

    Energy Technology Data Exchange (ETDEWEB)

    Ryan Davis; Nathan Bird; Rebecca Birx; Hal Knowles

    2011-04-04

    Acceleration has created an interactive energy tracking and visualization platform that supports decreasing electric, water, and gas usage. Homeowners have access to tools that allow them to gauge their use and track progress toward a smaller energy footprint. Real estate agents have access to consumption data, allowing for sharing a comparison with potential home buyers. Home builders have the opportunity to compare their neighborhood's energy efficiency with competitors. Home energy raters have a tool for gauging the progress of their clients after efficiency changes. And, social groups are able to help encourage members to reduce their energy bills and help their environment. EnergyIT.com is the business umbrella for all energy tracking solutions and is designed to provide information about our energy tracking software and promote sales. CompareAndConserve.com (Gainesville-Green.com) helps homeowners conserve energy through education and competition. ToolsForTenants.com helps renters factor energy usage into their housing decisions.

  4. The Creative Soccer Platform

    DEFF Research Database (Denmark)

    Johan Torp Rasmussen, Ludvig; Østergaard, Lars Domino

    2016-01-01

    Creativity is essential in soccer due to the unpredictable and complex situations occurring in the game, where stereotypical play gradually loses its efficiency. Further, creativity is an important psychological factor for the development of soccer expertise, and valuing creativity increases...... satisfaction and well-being. Although creative players are highly desired by coaches, the subject of cultivating creativity is mostly ignored and traditional training settings may even hamper the players' creativity. The purpose of this article is to introduce a novel approach for enhancing soccer players......' creativity, The Creative Soccer Platform (TCSP), and to demonstrate the implications of applying it in youth soccer practice, by means of soccer-specific creativity exercises. TCSP encompasses four theoretically based didactic principles (task focus, parallel thinking, horizontal thinking, and no experienced...

  5. Power Quality Indices Estimation Platform

    Directory of Open Access Journals (Sweden)

    Eliana I. Arango-Zuluaga

    2013-11-01

    Full Text Available An interactive platform for estimating the quality indices in single phase electric power systems is presented. It meets the IEEE 1459-2010 standard recommendations. The platform was developed in order to support teaching and research activities in electric power quality. The platform estimates the power quality indices from voltage and current signals using three different algorithms based on fast Fourier transform (FFT, wavelet packet transform (WPT and least squares method. The results show that the algorithms implemented are efficient for estimating the quality indices of the power and the platform can be used according to the objectives established. 

  6. Flexible experimental FPGA based platform

    DEFF Research Database (Denmark)

    Andersen, Karsten Holm; Nymand, Morten

    2016-01-01

    This paper presents an experimental flexible Field Programmable Gate Array (FPGA) based platform for testing and verifying digital controlled dc-dc converters. The platform supports different types of control strategies, dc-dc converter topologies and switching frequencies. The controller platform...... interface supporting configuration and reading of setup parameters, controller status and the acquisition memory in a simple way. The FPGA based platform, provides an easy way within education or research to use different digital control strategies and different converter topologies controlled by an FPGA...

  7. Product Platform Screening at LEGO

    DEFF Research Database (Denmark)

    Mortensen, Niels Henrik; Steen Jensen, Thomas; Nielsen, Ole Fiil

    2012-01-01

    Product platforms offer great benefits to companies developing new products in highly competitive markets. Literature describes how a single platform can be designed from a technical point of view, but rarely mentions how the process begins. How do companies identify possible platform candidates...... after a few changes had been applied to the initial process layout. This case study shows how companies must focus on a limited selection of simultaneous projects in order to keep focus. Primary stakeholders must be involved from the very beginning, and short presentations of the platform concepts...

  8. Platform evolution studies

    Science.gov (United States)

    Walton, Barbara A.

    1990-01-01

    The polar orbiting platform (POP), being developed by the Work Package 3 (WP3) Project at the Goddard Space Flight Center, will play a key role in the NASA Leadership Initiative, Mission to Planet Earth (MPE). It becomes, with the addition of payloads, an Earth observation satellite observatory. Mission to Planet Earth also has geostationary platforms (GEOP) as part of its global observational system. A study was begun in March 1988 to assess the applicability of the POP orbital replacement units (ORUs) for a geostationary Earth observing mission. Two test cases, representative of MPE payloads, were studied. Case A was used to emphasize the GEOP configuration and design; it used a Titan/Centaur to achieve orbit. Case B, considered to be much further in the future, included some assembly at the Space Station Freedom manned base and use of an orbital transfer vehicle to achieve orbit; requirements on the manned base to support such a mission were emphasized. The study found the POP systems more than adequate to meet GEOP requirements. Two types of changes were required for the POP ORUs: (1) modification to use only one surface for heat rejection; for the battery ORU, this meant 'opening up' the ORU to retain the radiator area with a corresponding decrease in depth; and (2) deletion of equipment not needed. The Case A configuration was shown to be within the planned capability of the Titan IV/Centaur. Assembly requirements were included for the Case B configuration, which is driven by the large microwave antennas of two of the payloads. The final review was April 19, 1989.

  9. Platform Performance and Challenges - using Platforms in Lego Company

    DEFF Research Database (Denmark)

    Munk, Lone; Mortensen, Niels Henrik

    2009-01-01

    This article studies the performance and challenges of using nine implemented product platforms in LEGO Company. Most of these do produce results, but do not meet their goals due to challenges in their usage in the daily product. The main challenges are that the platforms are not being used...

  10. Rapid prototyping of robotic platforms

    CSIR Research Space (South Africa)

    De Ronde, Willis

    2016-11-01

    Full Text Available Building a robotic platform from raw materials can take anything from a few weeks to a few years to complete, depending on the complexity and size of the platform. This paper aims to introduce a novel approach of using abrasive waterjet machining...

  11. Preparing for a Product Platform

    DEFF Research Database (Denmark)

    Fiil-Nielsen, Ole; Munk, Lone; Mortensen, Niels Henrik

    2005-01-01

    they lead to increased sales due to more customized product as well as decreased costs due to reuse, making a product development platform a very profitable strategy for product developing companies. A successful implementation of a product development platform is not straightforward though...

  12. Product Platform Screening at LEGO

    DEFF Research Database (Denmark)

    Mortensen, Niels Henrik; Steen Jensen, Thomas; Nielsen, Ole Fiil

    2012-01-01

    Product platforms offer great benefits to companies developing new products in highly competitive markets. Literature describes how a single platform can be designed from a technical point of view, but rarely mentions how the process begins. How do companies identify possible platform candidates......, and how do they assess if these candidates have enough potential to be worth implementing? Danish toy manufacturer LEGO has systematically gone through this process twice. The first time the results were poor; almost all platform candidates failed. The second time, though, has been largely successful...... after a few changes had been applied to the initial process layout. This case study shows how companies must focus on a limited selection of simultaneous projects in order to keep focus. Primary stakeholders must be involved from the very beginning, and short presentations of the platform concepts...

  13. ADAPTABLE ALTERNATE REALITY GAMES PLATFORM

    Directory of Open Access Journals (Sweden)

    Liviu-Adrian Cotfas

    2013-12-01

    Full Text Available In this paper, we present an alternate reality games platform that facilitates the creation of ARG projects with different themes and sizes. The platform is well integrated with the most important social media networks, thus facilitating both the involvement of the public and the creation of a more engaging interaction for the participants. A cloud-based architecture was used in order to allow the platform to easily accommodate projects of various sizes and to provide a good level of scalability. The platform is fully localizable in any language and multiple languages can be used at once to create projects that target users from different countries. An initial project that uses gamification to create an immersive learning environment has been created around the developed platform. The project combines professional and public feedback in order to provide an enhanced learning experience.

  14. Paper based electronics platform

    KAUST Repository

    Nassar, Joanna Mohammad

    2017-07-20

    A flexible and non-functionalized low cost paper-based electronic system platform fabricated from common paper, such as paper based sensors, and methods of producing paper based sensors, and methods of sensing using the paper based sensors are provided. A method of producing a paper based sensor can include the steps of: a) providing a conventional paper product to serve as a substrate for the sensor or as an active material for the sensor or both, the paper product not further treated or functionalized; and b) applying a sensing element to the paper substrate, the sensing element selected from the group consisting of a conductive material, the conductive material providing contacts and interconnects, sensitive material film that exhibits sensitivity to pH levels, a compressible and/or porous material disposed between a pair of opposed conductive elements, or a combination of two of more said sensing elements. The method of sensing can further include measuring, using the sensing element, a change in resistance, a change in voltage, a change in current, a change in capacitance, or a combination of any two or more thereof.

  15. Plat_Forms -- a contest: The web development platform comparison

    CERN Document Server

    Prechelt, Lutz

    2008-01-01

    "Plat_Forms" is a competition in which top-class teams of three programmers compete to implement the same requirements for a web-based system within 30 hours, each team using a different technology platform (Java EE, .NET, PHP, Perl, Python, or Ruby on Rails). The results will provide new insights into the real (rather than purported) pros, cons, and emergent properties of each platform. The evaluation will analyze many aspects of each solution, both external (usability, functionality, reliability, performance, etc.) and internal (structure, understandability, flexibility, etc.).

  16. Platform projections, compilers, interpreters and portability

    NARCIS (Netherlands)

    Bergstra, J.A.; Loots, M.E.

    1999-01-01

    Platform projection semantics extends projection semantics by means of the encapsulation of a processor used for program execution. Platform projection semantics abstracts from platform specific details. For a given program its platform projection semantics may be platform-independent. Two forms

  17. Renormalized Volume

    Science.gov (United States)

    Gover, A. Rod; Waldron, Andrew

    2017-09-01

    We develop a universal distributional calculus for regulated volumes of metrics that are suitably singular along hypersurfaces. When the hypersurface is a conformal infinity we give simple integrated distribution expressions for the divergences and anomaly of the regulated volume functional valid for any choice of regulator. For closed hypersurfaces or conformally compact geometries, methods from a previously developed boundary calculus for conformally compact manifolds can be applied to give explicit holographic formulæ for the divergences and anomaly expressed as hypersurface integrals over local quantities (the method also extends to non-closed hypersurfaces). The resulting anomaly does not depend on any particular choice of regulator, while the regulator dependence of the divergences is precisely captured by these formulæ. Conformal hypersurface invariants can be studied by demanding that the singular metric obey, smoothly and formally to a suitable order, a Yamabe type problem with boundary data along the conformal infinity. We prove that the volume anomaly for these singular Yamabe solutions is a conformally invariant integral of a local Q-curvature that generalizes the Branson Q-curvature by including data of the embedding. In each dimension this canonically defines a higher dimensional generalization of the Willmore energy/rigid string action. Recently, Graham proved that the first variation of the volume anomaly recovers the density obstructing smooth solutions to this singular Yamabe problem; we give a new proof of this result employing our boundary calculus. Physical applications of our results include studies of quantum corrections to entanglement entropies.

  18. Vertical Relationships within Platform Marketplaces

    Directory of Open Access Journals (Sweden)

    Mark J. Tremblay

    2016-07-01

    Full Text Available In two-sided markets a platform allows consumers and sellers to interact by creating sub-markets within the platform marketplace. For example, Amazon has sub-markets for all of the different product categories available on its site, and smartphones have sub-markets for different types of applications (gaming apps, weather apps, map apps, ridesharing apps, etc.. The network benefits between consumers and sellers depend on the mode of competition within the sub-markets: more competition between sellers lowers product prices, increases the surplus consumers receive from a sub-market, and makes platform membership more desirable for consumers. However, more competition also lowers profits for a seller which makes platform membership less desirable for a seller and reduces seller entry and the number of sub-markets available on the platform marketplace. This dynamic between seller competition within a sub-market and agents’ network benefits leads to platform pricing strategies, participation decisions by consumers and sellers, and welfare results that depend on the mode of competition. Thus, the sub-market structure is important when investigating platform marketplaces.

  19. Displacement Pumping of Liquids Radially Inward on Centrifugal Microfluidic Platforms in Motion

    Directory of Open Access Journals (Sweden)

    Eric D. Salin

    2011-12-01

    Full Text Available We describe two novel centrifugal microfluidic platform designs that enable passive pumping of liquids radially inward while the platform is in motion. The first design uses an immiscible liquid to displace an aqueous solution back towards the center of the platform, while the second design uses an arbitrary pumping liquid with a volume of air between it and the solution being pumped. Both designs demonstrated the ability to effectively pump 55% to 60% of the solution radially inward at rotational frequencies as low as 400 rpm (6.7 Hz to 700 rpm (11.7 Hz. The pumping operations reached completion within 120 s and 400 s respectively. These platform designs for passive pumping of liquids do not require moving parts or complex fabrication techniques. They offer great potential for increasing the number of sequential operations that can be performed on centrifugal microfluidic platforms, thereby reducing a fundamental limitation often associated with these platforms.

  20. Platform decisions supported by gaming

    DEFF Research Database (Denmark)

    Hansen, Poul H. Kyvsgård; Mikkola, Juliana Hsuan

    2007-01-01

    Platform is an ambiguous multidisciplinary concept. The philosophy behind it is easy to communicate and makes intuitively sense. However, the ease in communication does overshadow the high complexity when the concept is implemented. The practical industrial platform implementation challenge can...... is the application of on-line games in order to provide training for decision makers and in order to generate overview over the implications of platform decisions. However, games have to be placed in a context with other methods and we argue that a mixture of games, workshops, and simulations can provide improved...

  1. The External Payload Carrier - A Suborbital Research Platform

    Science.gov (United States)

    Schallhorn, Paul; Tatro, Charles; Kutter, Bernard; Szatkowski, Gerald; Stopnitzky, Benny; Bulk, Tim; Pitchford, Brian

    2011-01-01

    High altitude, suborbital research payloads are typically restricted to small packages (in terms of both volume and mass) due to the delivery platform employed. Sounding rockets that normally provide these services have payload capacities which severely limit the size and scope of the research to be performed. A new research platform is currently in the early development phase for large (both volume and mass) payload microgravity suborbital payloads seeking access to these regimes. The EXternal Payload Carrier (XPC) utilizes an open solid rocket motor position on the Atlas V vehicle and aerodynamically mimics the outer contour of a solid rocket motor. This presentation will detail the current state of the design and capability of XPC for potential future users.

  2. Microfluidic platforms for plant cells studies.

    Science.gov (United States)

    Sanati Nezhad, A

    2014-09-07

    Conventional methods of plant cell analysis rely on growing plant cells in soil pots or agarose plates, followed by screening the plant phenotypes in traditional greenhouses and growth chambers. These methods are usually costly, need a large number of experiments, suffer from low spatial resolution and disorderly growth behavior of plant cells, with lack of ability to locally and accurately manipulate the plant cells. Microfluidic platforms take advantage of miniaturization for handling small volume of liquids and providing a closed environment, with the purpose of in vitro single cell analysis and characterizing cell response to external cues. These platforms have shown their ability for high-throughput cellular analysis with increased accuracy of experiments, reduced cost and experimental times, versatility in design, ability for large-scale and combinatorial screening, and integration with other miniaturized sensors. Despite extensive research on animal cells within microfluidic environments for high-throughput sorting, manipulation and phenotyping studies, the application of microfluidics for plant cells studies has not been accomplished yet. Novel devices such as RootChip, RootArray, TipChip, and PlantChip developed for plant cells analysis, with high spatial resolution on a micrometer scale mimicking the internal microenvironment of plant cells, offering preliminary results on the capability of microfluidics to conquer the constraints of conventional methods. These devices have been used to study different aspects of plant cell biology such as gene expression, cell biomechanics, cellular mechanism of growth, cell division, and cells fusion. This review emphasizes the advantages of current microfluidic systems for plant science studies, and discusses future prospects of microfluidic platforms for characterizing plant cells response to diverse external cues.

  3. Cytostretch, an Organ-on-Chip Platform

    Directory of Open Access Journals (Sweden)

    Nikolas Gaio

    2016-07-01

    Full Text Available Organ-on-Chips (OOCs are micro-fabricated devices which are used to culture cells in order to mimic functional units of human organs. The devices are designed to simulate the physiological environment of tissues in vivo. Cells in some types of OOCs can be stimulated in situ by electrical and/or mechanical actuators. These actuations can mimic physiological conditions in real tissue and may include fluid or air flow, or cyclic stretch and strain as they occur in the lung and heart. These conditions similarly affect cultured cells and may influence their ability to respond appropriately to physiological or pathological stimuli. To date, most focus has been on devices specifically designed to culture just one functional unit of a specific organ: lung alveoli, kidney nephrons or blood vessels, for example. In contrast, the modular Cytostretch membrane platform described here allows OOCs to be customized to different OOC applications. The platform utilizes silicon-based micro-fabrication techniques that allow low-cost, high-volume manufacturing. We describe the platform concept and its modules developed to date. Membrane variants include membranes with (i through-membrane pores that allow biological signaling molecules to pass between two different tissue compartments; (ii a stretchable micro-electrode array for electrical monitoring and stimulation; (iii micro-patterning to promote cell alignment; and (iv strain gauges to measure changes in substrate stress. This paper presents the fabrication and the proof of functionality for each module of the Cytostretch membrane. The assessment of each additional module demonstrate that a wide range of OOCs can be achieved.

  4. A Review of Biomedical Centrifugal Microfluidic Platforms

    Directory of Open Access Journals (Sweden)

    Minghui Tang

    2016-02-01

    Full Text Available Centrifugal microfluidic or lab-on-a-disc platforms have many advantages over other microfluidic systems. These advantages include a minimal amount of instrumentation, the efficient removal of any disturbing bubbles or residual volumes, and inherently available density-based sample transportation and separation. Centrifugal microfluidic devices applied to biomedical analysis and point-of-care diagnostics have been extensively promoted recently. This paper presents an up-to-date overview of these devices. The development of biomedical centrifugal microfluidic platforms essentially covers two categories: (i unit operations that perform specific functionalities, and (ii systems that aim to address certain biomedical applications. With the aim to provide a comprehensive representation of current development in this field, this review summarizes progress in both categories. The advanced unit operations implemented for biological processing include mixing, valving, switching, metering and sequential loading. Depending on the type of sample to be used in the system, biomedical applications are classified into four groups: nucleic acid analysis, blood analysis, immunoassays, and other biomedical applications. Our overview of advanced unit operations also includes the basic concepts and mechanisms involved in centrifugal microfluidics, while on the other hand an outline on reported applications clarifies how an assembly of unit operations enables efficient implementation of various types of complex assays. Lastly, challenges and potential for future development of biomedical centrifugal microfluidic devices are discussed.

  5. PEEX Modelling Platform for Seamless Environmental Prediction

    Science.gov (United States)

    Baklanov, Alexander; Mahura, Alexander; Arnold, Stephen; Makkonen, Risto; Petäjä, Tuukka; Kerminen, Veli-Matti; Lappalainen, Hanna K.; Ezau, Igor; Nuterman, Roman; Zhang, Wen; Penenko, Alexey; Gordov, Evgeny; Zilitinkevich, Sergej; Kulmala, Markku

    2017-04-01

    The Pan-Eurasian EXperiment (PEEX) is a multidisciplinary, multi-scale research programme stared in 2012 and aimed at resolving the major uncertainties in Earth System Science and global sustainability issues concerning the Arctic and boreal Northern Eurasian regions and in China. Such challenges include climate change, air quality, biodiversity loss, chemicalization, food supply, and the use of natural resources by mining, industry, energy production and transport. The research infrastructure introduces the current state of the art modeling platform and observation systems in the Pan-Eurasian region and presents the future baselines for the coherent and coordinated research infrastructures in the PEEX domain. The PEEX modeling Platform is characterized by a complex seamless integrated Earth System Modeling (ESM) approach, in combination with specific models of different processes and elements of the system, acting on different temporal and spatial scales. The ensemble approach is taken to the integration of modeling results from different models, participants and countries. PEEX utilizes the full potential of a hierarchy of models: scenario analysis, inverse modeling, and modeling based on measurement needs and processes. The models are validated and constrained by available in-situ and remote sensing data of various spatial and temporal scales using data assimilation and top-down modeling. The analyses of the anticipated large volumes of data produced by available models and sensors will be supported by a dedicated virtual research environment developed for these purposes.

  6. Development of a Very Dense Liquid Cooled Compute Platform

    Energy Technology Data Exchange (ETDEWEB)

    Hughes, Phillip N.; Lipp, Robert J.

    2013-12-10

    The objective of this project was to design and develop a prototype very energy efficient high density compute platform with 100% pumped refrigerant liquid cooling using commodity components and high volume manufacturing techniques. Testing at SLAC has indicated that we achieved a DCIE of 0.93 against our original goal of 0.85. This number includes both cooling and power supply and was achieved employing some of the highest wattage processors available.

  7. NASA's geostationary communications platform program

    Science.gov (United States)

    Ramler, J.; Durrett, R.

    1984-01-01

    This paper reviews recent trends in communications satellites and explains NASA's current interest in geostationary communications platforms. Large communications platforms capable of supporting multiple payloads with common utilities have been examined in a number of studies since 1974 and appear to offer a number of potential advantages. In 1981, an Industry Briefing and Workshop sponsord by NASA focused on the institutional, operational and technical issues that will influence the implementation of geostationary platforms. The workshop identified numerous issues and problem areas that needed more detailed study. To address the issues/problems identified, a NASA geostationary communications platform program has been developed. This program is described, focusing on the initial studies to be performed.

  8. Platform attitude data acquisition system

    Digital Repository Service at National Institute of Oceanography (India)

    Afzulpurkar, S.

    A system for automatic acquisition of underwater platform attitude data has been designed, developed and tested in the laboratory. This is a micro controller based system interfacing dual axis inclinometer, high-resolution digital compass...

  9. Elevated Fixed Platform Test Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Elevated Fixed Platform (EFP) is a helicopter recovery test facility located at Lakehurst, NJ. It consists of a 60 by 85 foot steel and concrete deck built atop...

  10. Platforms for Innovation and Internationalization

    DEFF Research Database (Denmark)

    Rasmussen, Erik Stavnsager; Petersen, Nicolaj Hannesbo

    2017-01-01

    The high-tech global startup has many challenges related to both innovation and internationalization. From a Danish cluster of Welfare Tech firms, eight innovative and international firms were selected and interviewed. Such firms typically have to be agile and operate in virtual networks in almost...... all parts of their value chains. This article contributes to the understanding of how innovation and internationalization to a great extent are interlinked. The firms have developed a core product or service offering, which the firms often describe as “a platform”. Around the platform, they develop...... their products and services for new customers and users in new countries. The firms have to sustain a strong focus on the platform while at the same time developing their platform solution for new products, new customers, and new markets. This pivoting makes it possible to use the platform in a new context...

  11. Disentangling Competition Among Platform Driven Strategic Groups

    DEFF Research Database (Denmark)

    Kazan, Erol; Tan, Chee-Wee; Lim, Eric

    2015-01-01

    In platform-driven markets, competitive advantage is derived from superior platform design and configurations. For this reason, platform owners strive to create unique and inimitable platform configurals to maintain and extend their competitiveness within network economies. To disentangle firm...... competition within platform-driven markets, we opted for the UK mobile payment market as our empirical setting. By embracing the theoretical lens of strategic groups and digital platforms, this study supplements prior research by deriving a taxonomy of platform-driven strategic groups that is grounded...... on competitive attributes of platform- driven markets; namely interfirm modularity and strategic linkages....

  12. Disentangling Competition Among Platform Driven Strategic Groups

    DEFF Research Database (Denmark)

    Kazan, Erol; Tan, Chee-Wee; Lim, Eric

    2015-01-01

    competition within platform-driven markets, we opted for the UK mobile payment market as our empirical setting. By embracing the theoretical lens of strategic groups and digital platforms, this study supplements prior research by deriving a taxonomy of platform-driven strategic groups that is grounded......In platform-driven markets, competitive advantage is derived from superior platform design and configurations. For this reason, platform owners strive to create unique and inimitable platform configurals to maintain and extend their competitiveness within network economies. To disentangle firm...... on competitive attributes of platform- driven markets; namely interfirm modularity and strategic linkages....

  13. 基于软件体系结构的可视化软件开发平台%Platform for Visualization Software Based on Software Architecture

    Institute of Scientific and Technical Information of China (English)

    胡华; 林昌东

    2003-01-01

    Platform for visualization software is a kind of large and complex software system, the work to design and evolve platform for visualization software is also a complex work. This paper proposes using software architecture to analyze and evolve a large visualization platform based plane data to a visualization platform with ability of processing both plane and volume. The result of this paper proves the reasonability of our method.

  14. A mouse informatics platform for phenotypic and translational discovery.

    Science.gov (United States)

    Ring, Natalie; Meehan, Terrence F; Blake, Andrew; Brown, James; Chen, Chao-Kung; Conte, Nathalie; Di Fenza, Armida; Fiegel, Tanja; Horner, Neil; Jacobsen, Julius O B; Karp, Natasha; Lawson, Thomas; Mason, Jeremy C; Matthews, Peter; Morgan, Hugh; Relac, Mike; Santos, Luis; Smedley, Damian; Sneddon, Duncan; Pengelly, Alice; Tudose, Ilinca; Warren, Jonathan W G; Westerberg, Henrik; Yaikhom, Gagarine; Parkinson, Helen; Mallon, Ann-Marie

    2015-10-01

    The International Mouse Phenotyping Consortium (IMPC) is providing the world's first functional catalogue of a mammalian genome by characterising a knockout mouse strain for every gene. A robust and highly structured informatics platform has been developed to systematically collate, analyse and disseminate the data produced by the IMPC. As the first phase of the project, in which 5000 new knockout strains are being broadly phenotyped, nears completion, the informatics platform is extending and adapting to support the increasing volume and complexity of the data produced as well as addressing a large volume of users and emerging user groups. An intuitive interface helps researchers explore IMPC data by giving overviews and the ability to find and visualise data that support a phenotype assertion. Dedicated disease pages allow researchers to find new mouse models of human diseases, and novel viewers provide high-resolution images of embryonic and adult dysmorphologies. With each monthly release, the informatics platform will continue to evolve to support the increased data volume and to maintain its position as the primary route of access to IMPC data and as an invaluable resource for clinical and non-clinical researchers.

  15. High throughput miniature drug-screening platform using bioprinting technology.

    Science.gov (United States)

    Rodríguez-Dévora, Jorge I; Zhang, Bimeng; Reyna, Daniel; Shi, Zhi-dong; Xu, Tao

    2012-09-01

    In the pharmaceutical industry, new drugs are tested to find appropriate compounds for therapeutic purposes for contemporary diseases. Unfortunately, novel compounds emerge at expensive prices and current target evaluation processes have limited throughput, thus leading to an increase of cost and time for drug development. This work shows the development of the novel inkjet-based deposition method for assembling a miniature drug-screening platform, which can realistically and inexpensively evaluate biochemical reactions in a picoliter-scale volume at a high speed rate. As proof of concept, applying a modified Hewlett Packard model 5360 compact disc printer, green fluorescent protein expressing Escherichia coli cells along with alginate gel solution have been arrayed on a coverslip chip under a repeatable volume of 180% ± 26% picoliters per droplet; subsequently, different antibiotic droplets were patterned on the spots of cells to evaluate the inhibition of bacteria for antibiotic screening. The proposed platform was compared to the current screening process, validating its effectiveness. The viability and basic function of the printed cells were evaluated, resulting in cell viability above 98% and insignificant or no DNA damage to human kidney cells transfected. Based on the reduction of investment and compound volume used by this platform, this technique has the potential to improve the actual drug discovery process at its target evaluation stage.

  16. NASA Earth Exchange: A Collaborative Earth Science Platform

    Science.gov (United States)

    Nemani, R. R.; Votava, P.; Michaelis, A.; Melton, F. S.; Hashimoto, H.; Milesi, C.; Wang, W.; Ganguly, S.

    2010-12-01

    The NASA Earth Exchange (NEX) is a collaboration platform for the Earth science community creating new ways for scientific interaction and knowledge sharing. Funded through ARRA, NEX combines state-of-the-art supercomputing, Earth system modeling, workflow management, NASA remote sensing data feeds, and a social networking platform to deliver a complete work environment in which users can explore and analyze large datasets, run modeling codes, collaborate on new or existing projects, and quickly share results among the Earth science communities. The work environment provides NEX members with community supported modeling, analysis and visualization software in conjunction with datasets that are common to the Earth systems science domain. By providing data, software, and large-scale computing power together in a flexible framework, NEX reduces the need for duplicated efforts in downloading data, developing pre-processing software tools, and expanding local compute infrastructures—while accelerating fundamental research, development of new applications, and reducing project costs. The social networking platform provides a forum for NEX members to efficiently share datasets, results, algorithms, codes, and expertise with other members. Since all members' work environments reside on the collaborative platform, sharing may be done without the transfer of large volumes of data or the porting of complex codes—making NEX an ideal platform for building upon and exchanging research, and fostering innovation. Architecture of NEX integrating social networking, super-computing and data center. The prototyping facility allows users to test their models, algorithms prior to deploying them on the super-computers when required.

  17. A Typology of Multi-sided Platforms

    DEFF Research Database (Denmark)

    Staykova, Kalina Stefanova; Damsgaard, Jan

    2015-01-01

    exemplary cases which allow us to illustrate the platform heterogeneity and to support new MSPs typology. As examples we include a physical two-sided platform (Gatwick Airport) that adds a third side, a digital one-sided platform transformed into being two-sided (Pingit) and a digital one-sided platform......In this paper we address how the composition of a platform impacts the platform’s business model. By platform’s business model we mean platform features, platform architecture and platform governance. To this end, we construct the Platform Business Model Framework. We apply the framework to three...... in several configurations. The particular platform architecture can explain the difficulties in designing a viable business models for platforms....

  18. Stratifying the Develoment of Product Platforms

    DEFF Research Database (Denmark)

    Sköld, Martin; Karlsson, Christer

    2013-01-01

    companies develop platforms for different aims, purposes, and product scopes. Following on from this, the requirements for platform development resources, the ways of organizing platform development, and the implications for management styles have not been explored and are presumably varying. To start...... influencing the project length, requirements for platform development resources, principles for organizing, and implications for management styles....

  19. New offshore platform in the Mexican Gulf

    Energy Technology Data Exchange (ETDEWEB)

    Beisel, T.

    1982-04-01

    After a construction period of only 10 months, the second steel Offshore platform was recently completed in the Mexican Gulf. The pattern for this structure was the Cognac platform. The erection of the new platform, called the 'Cerveza' platform, is described in the article.

  20. Centrifuge-Based Fluidic Platforms

    Science.gov (United States)

    Zoval, Jim; Jia, Guangyao; Kido, Horacio; Kim, Jitae; Kim, Nahui; Madou, Marc

    In this chapter centrifuge-based microfluidic platforms are reviewed and compared with other popular microfluidic propulsion methods. The underlying physical principles of centrifugal pumping in microfluidic systems are presented and the various centrifuge fluidic functions such as valving, decanting, calibration, mixing, metering, heating, sample splitting, and separation are introduced. Those fluidic functions have been combined with analytical measurements techniques such as optical imaging, absorbance and fluorescence spectroscopy and mass spectrometry to make the centrifugal platform a powerful solution for medical and clinical diagnostics and high-throughput screening (HTS) in drug discovery. Applications of a compact disc (CD)-based centrifuge platform analyzed in this review include: two-point calibration of an optode-based ion sensor, an automated immunoassay platform, multiple parallel screening assays and cellular-based assays. The use of modified commercial CD drives for high-resolution optical imaging is discussed as well. From a broader perspective, we compare the technical barriers involved in applying microfluidics for sensing and diagnostic as opposed to applying such techniques to HTS. The latter poses less challenges and explains why HTS products based on a CD fluidic platform are already commercially available, while we might have to wait longer to see commercial CD-based diagnostics.

  1. Platforms for Innovation and Internationalization

    Directory of Open Access Journals (Sweden)

    Erik Stavnsager Rasmussen

    2017-05-01

    Full Text Available The high-tech global startup has many challenges related to both innovation and internationalization. From a Danish cluster of Welfare Tech firms, eight innovative and international firms were selected and interviewed. Such firms typically have to be agile and operate in virtual networks in almost all parts of their value chains. This article contributes to the understanding of how innovation and internationalization to a great extent are interlinked. The firms have developed a core product or service offering, which the firms often describe as “a platform”. Around the platform, they develop their products and services for new customers and users in new countries. The firms have to sustain a strong focus on the platform while at the same time developing their platform solution for new products, new customers, and new markets. This pivoting makes it possible to use the platform in a new context but is highly demanding for the firms. They need to be extremely agile and fast-moving but at the same time still to have a focus on the core of the firm: the platform.

  2. Renormalized Volume

    CERN Document Server

    Gover, A Rod

    2016-01-01

    For any conformally compact manifold with hypersurface boundary we define a canonical renormalized volume functional and compute an explicit, holographic formula for the corresponding anomaly. For the special case of asymptotically Einstein manifolds, our method recovers the known results. The anomaly does not depend on any particular choice of regulator, but the coefficients of divergences do. We give explicit formulae for these divergences valid for any choice of regulating hypersurface; these should be relevant to recent studies of quantum corrections to entanglement entropies. The anomaly is expressed as a conformally invariant integral of a local Q-curvature that generalizes the Branson Q-curvature by including data of the embedding. In each dimension this canonically defines a higher dimensional generalization of the Willmore energy/rigid string action. We show that the variation of these energy functionals is exactly the obstruction to solving a singular Yamabe type problem with boundary data along the...

  3. Persistent Monitoring Platforms Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Bennett, C L

    2007-02-22

    This project was inspired and motivated by the need to provide better platforms for persistent surveillance. In the years since the inception of this work, the need for persistence of surveillance platforms has become even more widely appreciated, both within the defense community and the intelligence community. One of the most demanding technical requirements for such a platform involves the power plant and energy storage system, and this project concentrated almost exclusively on the technology associated with this system for a solar powered, high altitude, unmanned aircraft. An important realization for the feasibility of such solar powered aircraft, made at the outset of this project, was that thermal energy may be stored with higher specific energy density than for any other known practical form of rechargeable energy storage. This approach has proved to be extraordinarily fruitful, and a large number of spin-off applications of this technology were developed in the course of this project.

  4. Cerveza platforms offer economic options

    Energy Technology Data Exchange (ETDEWEB)

    Leblanc, L.A.

    1982-08-01

    Two single-piece platforms, Cerveze and Cerveza Ligera, were installed by Union Oil Co. in 925-935 ft of water. The technology and equipment used for the two platforms can be used for units to a depth of 1,400 ft in mild climates and to 1,000 ft in more critical weather areas such as the North Sea. The significant improvements in design and procedures in the construction and installation of the Cerveza Ligera platform are: (1) four leg structure, as opposed to eight, requiring less steel; (2) simplified fabrication; and (3) quicker installation. The most significant area of improvement in the Ligera project compared with Cerveza was in communications. Communications between naval architects and onshore launch foremen during loadout, and between surveyors and tug captains during positioning, are cited as examples.

  5. Tax Responses in Platform Industries

    DEFF Research Database (Denmark)

    Kind, Hans Jarle; Köthenbürger, Marko; Schjelderup, Guttorm

    Two-sided platform firms serve distinct customer groups that are connected through interdependent demand, and include major businesses such as the media industry, banking, and the software industry. A well known result of tax incidence is that consumers of a more heavily taxed good pay a higher...... price and thus buy less of the good. The present paper shows that this result need not hold in a two-sided market. On the contrary, a higher ad valorem tax may lower end-user prices and spur sales. Thus, two-sided platform firms may not at all engage in tax shifting via price increases. We further show...

  6. Moodle vs. Social Media Platforms

    DEFF Research Database (Denmark)

    Gulieva, Valeria

    Given the competition coming from various social media platforms, it is explored in this paper how students could be encouraged to use Moodle more proactively during their studies. Moodle is a course management system for online learning. It is designed to be a flexible template-based system, which......, known and widely used social platforms. It might be also due to the fact that students do not see the benefits in investing time and efforts in learning the new system. Another reason might be the mandatory nature of Moodle, i.e., it is imposed on students, rather than a free choice – and this might...

  7. A practice scaffolding interactive platform

    DEFF Research Database (Denmark)

    Bundsgaard, Jeppe

    2009-01-01

    , structures the students' activity, and interactively supports subject learning. A PracSIP facilitates students' development of complex competencies, and at the same time it supports the students' development of skills defined in the curriculum. The paper introduces the concept, presents the theoretical......A Practice Scaffolding Interactive Platform (PracSIP) is a social learning platform which supports students in collaborative project based learning by simulating a professional practice. A PracSIP puts the core tools of the simulated practice at the students' disposal, it organizes collaboration...

  8. 2009 Analysis Platform Review Report

    Energy Technology Data Exchange (ETDEWEB)

    Ferrell, John [Office of Energy Efficiency and Renewable Energy (EERE), Washington, DC (United States

    2009-12-01

    This document summarizes the recommendations and evaluations provided by an independent external panel of experts at the U.S. Department of Energy Biomass Program’s Analysis platform review meeting, held on February 18, 2009, at the Marriott Residence Inn, National Harbor, Maryland.

  9. 2009 Infrastructure Platform Review Report

    Energy Technology Data Exchange (ETDEWEB)

    Ferrell, John [Office of Energy Efficiency and Renewable Energy (EERE), Washington, DC (United States)

    2009-12-01

    This document summarizes the recommendations and evaluations provided by an independent external panel of experts at the U.S. Department of Energy Biomass program‘s Infrastructure platform review meeting, held on February 19, 2009, at the Marriott Residence Inn, National Harbor, Maryland.

  10. Venus Atmospheric Maneuverable Platform (VAMP)

    Science.gov (United States)

    Polidan, R.; Lee, G.; Sokol, D.; Griffin, K.; Bolisay, L.

    2014-05-01

    VAMP is a long lived, semi-buoyant, atmospheric “rover” that deploys in orbit, enters the Venus atmosphere and flies in the Venus atmosphere between 55 and 70 km for up to one year as a platform to address VEXAG goals I.A, I.B, and I.C.

  11. Utilizing platforms in industrialized construction

    DEFF Research Database (Denmark)

    Bonev, Martin; Wörösch, Michael; Hvam, Lars

    2015-01-01

    Purpose – The purpose of this paper is to explore the development of a platform-based projectexecution in the industrialised construction sector, with a focus on systematically balancing cost andvalue. Offering custom-tailored buildings at reasonable costs has been a growing concern for manyconst...

  12. Generational Transitions in Platform Markets

    DEFF Research Database (Denmark)

    Kretschmer, Tobias; Claussen, Jörg

    2016-01-01

    The introduction of a new product generation forces incumbents in platform markets to rebuild their installed base of complementary products. Using three different data sets on the U.S. market for video game consoles, we show that incumbents can, to some extent, substitute for rebuilding their new...

  13. Analysis of offshore jacket platform

    Digital Repository Service at National Institute of Oceanography (India)

    Harish, N.; Mandal, S.; Shanthala, B.; Rao, S.

    -Rohman, M., ‘Multi-loop feedback control of offshore steel jacket platforms’, Computers & Structures 70, 1999, 185–202. 11.Yamamoto, I., Terada, Y., and Yokokura, K., ‘An application of a position keeping control system to floating offshore platform...

  14. Tax Responses in Platform Industries

    DEFF Research Database (Denmark)

    Kind, Hans Jarle; Köthenbürger, Marko; Schjelderup, Guttorm

    Two-sided platform firms serve distinct customer groups that are connected through interdependent demand, and include major businesses such as the media industry, banking, and the software industry. A well known result of tax incidence is that consumers of a more heavily taxed good pay a higher...

  15. 2009 Feedstocks Platform Review Report

    Energy Technology Data Exchange (ETDEWEB)

    Ferrell, John [Office of Energy Efficiency and Renewable Energy (EERE), Washington, DC (United States)

    2009-12-01

    This document summarizes the recommendations and evaluations provided by an independent external panel of experts at the U.S. Department of Energy Biomass Program‘s Feedstock platform review meeting, held on April 8–10, 2009, at the Grand Hyatt Washington, Washington, D.C.

  16. Parallel microwave chemistry in silicon carbide microtiter platforms: a review.

    Science.gov (United States)

    Kappe, C Oliver; Damm, Markus

    2012-02-01

    In this review, applications of silicon carbide-based microtiter platforms designed for use in combination with dedicated multimode microwave reactors are described. These platforms are employed not only for the efficient parallel synthesis of compound libraries, but also in the context of high-throughput reaction screening/optimization and a number of other (bio)analytical and biomedical applications. Since the semiconducting plate material (silicon carbide) is strongly microwave absorbing and possesses high thermal conductivity, no temperature gradients across the microtiter plate exist. Therefore, many of the disadvantages experienced in attempting to perform microtiter plate chemistry under conventional microwave conditions can be eliminated. In general, the silicon carbide-based microtiter platforms allow sealed vessel processing (either directly in the well or in glass vials placed into the wells) of volumes ranging from 0.02-3.0 mL at a maximum temperature/pressure limit of 200°C/20 bar. Depending on the specific plate and rotor configuration, a maximum of 80-192 transformations can be carried out in parallel in a single microwave irradiation experiment under strict temperature control. A platform type utilizing HPLC/GC vials as reaction vessels allows analysis directly from the reaction vessel eliminating the need for a transfer step from the reaction to the analysis vial. The latter system is particularly useful for analytical applications as well as reaction optimization/screening.

  17. FSW of Aluminum Tailor Welded Blanks across Machine Platforms

    Energy Technology Data Exchange (ETDEWEB)

    Hovanski, Yuri; Upadhyay, Piyush; Carlson, Blair; Szymanski, Robert; Luzanski, Tom; Marshall, Dustin

    2015-02-16

    Development and characterization of friction stir welded aluminum tailor welded blanks was successfully carried out on three separate machine platforms. Each was a commercially available, gantry style, multi-axis machine designed specifically for friction stir welding. Weld parameters were developed to support high volume production of dissimilar thickness aluminum tailor welded blanks at speeds of 3 m/min and greater. Parameters originally developed on an ultra-high stiffness servo driven machine where first transferred to a high stiffness servo-hydraulic friction stir welding machine, and subsequently transferred to a purpose built machine designed to accommodate thin sheet aluminum welding. The inherent beam stiffness, bearing compliance, and control system for each machine were distinctly unique, which posed specific challenges in transferring welding parameters across machine platforms. This work documents the challenges imposed by successfully transferring weld parameters from machine to machine, produced from different manufacturers and with unique control systems and interfaces.

  18. Product Platform Development in Industrial Networks

    DEFF Research Database (Denmark)

    Karlsson, Christer; Skold, Martin

    2011-01-01

    The article examines the strategic issues involved in the deployment of product platform development in an industrial network. The move entails identifying the types and characteristics of generically different product platform strategies and clarifying strategic motives and differences. Number...

  19. Parametric modelling of nonstationary platform deck motions

    Digital Repository Service at National Institute of Oceanography (India)

    Mandal, S.

    -sense-stationary processes. Then the time series are modelled by the maximum entropy method which is formulated here for spectral estimation of platform deck displacements. The lower order maximum entropy spectra of nonstationary platform deck displacements are compared...

  20. Front-end conceptual platform modeling

    DEFF Research Database (Denmark)

    Guðlaugsson, Tómas Vignir; Ravn, Poul Martin; Mortensen, Niels Henrik

    2014-01-01

    Platform thinking has been the subject of investigation and deployment in many projects in both academia and industry. Most contributions involve the restructuring of product programs, and only a few support front-end development of a new platform in parallel with technology development....... This contribution deals with the development of product platforms in front-end projects and introduces a modeling tool: the Conceptual Product Platform model. State of the art within platform modeling forms the base of a modeling formalism for a Conceptual Product Platform model. The modeling formalism is explored...... through an example and applied in a case in which the Conceptual Product Platform model has supported the front-end development of a platform for an electro-active polymer technology. The case describes the contents of the model and how its application supported the development work in the project...

  1. The Logic of Digital Platform Disruption

    DEFF Research Database (Denmark)

    Kazan, Erol; Tan, Chee-Wee; Lim, Eric T. K.

    Digital platforms are disruptive IT artifacts, because they facilitate the quick release of innovative platform derivatives from third parties (e.g., apps). This study endeavours to unravel the disruptive potential, caused by distinct designs and configurations of digital platforms on market...... environments. We postulate that the disruptive potential of digital platforms is determined by the degree of alignment among the business, technology and platform profiles. Furthermore, we argue that the design and configuration of the aforementioned three elements dictates the extent to which open innovation...... is permitted. To shed light on the disruptive potential of digital platforms, we opted for payment platforms as our unit of analysis. Through interviews with experts and payment providers, we seek to gain an in-depth appreciation of how contemporary digital payment platforms are designed and configured...

  2. Modeling and analysis of offshore jacket platform

    Digital Repository Service at National Institute of Oceanography (India)

    Mohan, P.; Sidhaarth, K.R.A.; SanilKumar, V.

    This paper details the results obtained from static analysis, considering both operational and ultimate limit state performance characteristics of a jacket platform, designed at Mumbai high basin. The existing platforms at Mumbai high region...

  3. The Logic of Digital Platform Disruption

    DEFF Research Database (Denmark)

    Kazan, Erol; Tan, Chee-Wee; Lim, Eric T. K.

    Digital platforms are disruptive IT artifacts, because they facilitate the quick release of innovative platform derivatives from third parties (e.g., apps). This study endeavours to unravel the disruptive potential, caused by distinct designs and configurations of digital platforms on market...... environments. We postulate that the disruptive potential of digital platforms is determined by the degree of alignment among the business, technology and platform profiles. Furthermore, we argue that the design and configuration of the aforementioned three elements dictates the extent to which open innovation...... is permitted. To shed light on the disruptive potential of digital platforms, we opted for payment platforms as our unit of analysis. Through interviews with experts and payment providers, we seek to gain an in-depth appreciation of how contemporary digital payment platforms are designed and configured...

  4. Product Platform Development in Industrial Networks

    DEFF Research Database (Denmark)

    Karlsson, Christer; Skold, Martin

    2011-01-01

    The article examines the strategic issues involved in the deployment of product platform development in an industrial network. The move entails identifying the types and characteristics of generically different product platform strategies and clarifying strategic motives and differences. Number...

  5. Software development on the SAP HANA platform

    CERN Document Server

    Walker, Mark

    2013-01-01

    Software Development on the SAP HANA Platform is a general tutorial guide to SAP HANA.This book is written for beginners to the SAP HANA platform. No knowledge of SAP HANA is necessary to start using this book.

  6. Hierarchical DSE for multi-ASIP platforms

    DEFF Research Database (Denmark)

    Micconi, Laura; Corvino, Rosilde; Gangadharan, Deepak;

    2013-01-01

    This work proposes a hierarchical Design Space Exploration (DSE) for the design of multi-processor platforms targeted to specific applications with strict timing and area constraints. In particular, it considers platforms integrating multiple Application Specific Instruction Set Processors (ASIPs...

  7. A Platform for Spreadsheet Composition

    CERN Document Server

    Baglietto, Pierpaolo; Mangiante, Simone; Maresca, Massimo; Parodi, Andrea; Stecca, Michele

    2011-01-01

    A huge amount of data is everyday managed in large organizations in many critical business sectors with the support of spreadsheet applications. The process of elaborating spreadsheet data is often performed in a distributed, collaborative way, where many actors enter data belonging to their local business domain to contribute to a global business view. The manual fusion of such data may lead to errors in copy-paste operations, loss of alignment and coherency due to multiple spreadsheet copies in circulation, as well as loss of data due to broken cross-spreadsheet links. In this paper we describe a methodology, based on a Spreadsheet Composition Platform, which greatly reduces these risks. The proposed platform seamlessly integrates the distributed spreadsheet elaboration, supports the commonly known spreadsheet tools for data processing and helps organizations to adopt a more controlled and secure environment for data fusion.

  8. Platform-Independent Courseware Sharing

    Directory of Open Access Journals (Sweden)

    Takao Shimomura

    2013-04-01

    Full Text Available Courseware distribution between different platforms is the major issue of current e-Learning. SCORM (Sharable Content Object Reference Model is one of the solutions for courseware sharing. However, to make SCORM-conformable courseware, some knowledge about HTML and JavaScript is required. This paper presents a SWF (Sharable Web Fragment-based e-Learning system, where courseware is created with sharable Web fragments such as Web pages, images and other resources, and the courseware can be distributed to another platform by export and import facilities. It also demonstrates how to export a subject that contains assignments and problems and how to import the whole subject, only the assignments, or only the problems. The exported meta-information is architecture-independent and provides a model of courseware distribution.

  9. Stabilisation problem in biaxial platform

    Directory of Open Access Journals (Sweden)

    Lindner Tymoteusz

    2016-12-01

    Full Text Available The article describes investigation of rolling ball stabilization problem on a biaxial platform. The aim of the control system proposed here is to stabilize ball moving on a plane in equilibrium point. The authors proposed a control algorithm based on cascade PID and they compared it with another control method. The article shows the results of the accuracy of ball stabilization and influence of applied filter on the signal waveform. The application used to detect the ball position measured by digital camera has been written using a cross platform .Net wrapper to the OpenCV image processing library - EmguCV. The authors used the bipolar stepper motor with dedicated electronic controller. The data between the computer and the designed controller are sent with use of the RS232 standard. The control stand is based on ATmega series microcontroller.

  10. DATABASE REPLICATION IN HETEROGENOUS PLATFORM

    Directory of Open Access Journals (Sweden)

    Hendro Nindito

    2014-01-01

    Full Text Available The application of diverse database technologies in enterprises today is increasingly a common practice. To provide high availability and survavibality of real-time information, a database replication technology that has capability to replicate databases under heterogenous platforms is required. The purpose of this research is to find the technology with such capability. In this research, the data source is stored in MSSQL database server running on Windows. The data will be replicated to MySQL running on Linux as the destination. The method applied in this research is prototyping in which the processes of development and testing can be done interactively and repeatedly. The key result of this research is that the replication technology applied, which is called Oracle GoldenGate, can successfully manage to do its task in replicating data in real-time and heterogeneous platforms.

  11. YARP: Yet Another Robot Platform

    Directory of Open Access Journals (Sweden)

    Lorenzo Natale

    2008-11-01

    Full Text Available We describe YARP, Yet Another Robot Platform, an open-source project that encapsulates lessons from our experience in building humanoid robots. The goal of YARP is to minimize the effort devoted to infrastructure-level software development by facilitating code reuse, modularity and so maximize research-level development and collaboration. Humanoid robotics is a "bleeding edge" field of research, with constant flux in sensors, actuators, and processors. Code reuse and maintenance is therefore a significant challenge. We describe the main problems we faced and the solutions we adopted. In short, the main features of YARP include support for inter-process communication, image processing as well as a class hierarchy to ease code reuse across different hardware platforms. YARP is currently used and tested on Windows, Linux and QNX6 which are common operating systems used in robotics.

  12. Multithreading platform for multimedia applications

    Science.gov (United States)

    Koster, Rainer; Kramp, Thorsten

    2000-12-01

    Complex multimedia applications have diverse resource and timing requirements. A platform for building such programs therefore should supply the developer with mechanisms for managing concurrency, communication, and real-time constraints but should remain flexible with regard to scheduling policies and interaction models. We have developed such a platform consisting of a user-level threads package and operating system extensions. The threads package offers a message-based threading model uniformly integrating synchronous and asynchronous communication, inter-thread synchronization, and signal handling as well as real-time functionality and application-specific scheduling. To support this user-space flexibility an upcall mechanism links the user-level scheduler to the kernel.

  13. Stabilisation problem in biaxial platform

    Science.gov (United States)

    Lindner, Tymoteusz; Rybarczyk, Dominik; Wyrwał, Daniel

    2016-12-01

    The article describes investigation of rolling ball stabilization problem on a biaxial platform. The aim of the control system proposed here is to stabilize ball moving on a plane in equilibrium point. The authors proposed a control algorithm based on cascade PID and they compared it with another control method. The article shows the results of the accuracy of ball stabilization and influence of applied filter on the signal waveform. The application used to detect the ball position measured by digital camera has been written using a cross platform .Net wrapper to the OpenCV image processing library - EmguCV. The authors used the bipolar stepper motor with dedicated electronic controller. The data between the computer and the designed controller are sent with use of the RS232 standard. The control stand is based on ATmega series microcontroller.

  14. Climate News Across Media Platforms

    DEFF Research Database (Denmark)

    Eskjær, Mikkel Fugl

    2015-01-01

    In a changing media landscape marked by technological, institutional and cultural convergence, comparative and cross-media content analysis represents a valuable analytical tool in mapping the diverse channels of climate change communication. This paper presents a comparative study of climate...... change news on five different media platforms: newspapers, television, radio, web-news and mobile news. It investigates the themes and actors represented in public climate change communication as well as the diverse possibilities of participating in public debates and information sharing. By combining...... quantitative and qualitative content analysis the paper documents and explores the extent and character of climate change news across different media platforms. The study aims at contributing to the on-going assessment of how news media are addressing climate change at a time when old and new media...

  15. Biofacies evolution in the Triassic platforms of the Dolomites, Italy

    Directory of Open Access Journals (Sweden)

    Franco Russo

    2005-10-01

    Full Text Available The Triassic of the Dolomites includes many carbonate platform generations, ranging in age from the Anisian to the Norian-Rhaetian. After the Permian-Triassic biological crisis, “reef” communities reappeared during the Anisian time. These buildups were generally characterized by a limited relief, lacking any primary skeletal framework and evidence of syndepositional cementation. The microfacies are dominated by micrites, mainly allochthonous or detrital in origin. The sparse biota are generally binder and buffler organisms, such as dasycladacean algae, sphinctozoans and briozoans.The second generation of carbonate buildups (late Anisian–early Ladinian, Sciliar Fm are dominated by syndepositional cements (e.g. Marmolada Platform. These cements represent the main component of margin and upper slope facies. They form more or less isolated or laterally linked bodies: the “evinosponges”. During the late Ladinian and Carnian p.p., the post-volcanic platforms developed (Cassian Dolomite. The microfacies of these platforms manly consist of micrites, cements and skeletons. The automicrites constitute more than 50% of the rock volume, the cements the 20%, and the skeletal organisms less than the 10%. The metazoan contribution is subordinated to that of skeletal cyanobacteria, like Cladogirvanella cipitensis and microproblematica, like Tubyphites. The primary marine cements provide evidence of a widespread early syndepositional lithification. Towards the top of Julian Substage (Carnian, at the base of the Heiligkreutz/Dürrenstein Formation (i.e. Alpe di Specie, small calcareous bioconstructions, interpreted as patch-reefs, show a much more “modern” faunal association. For the first time in the Triassic, a primary skeletal framework developed, largely formed by calcified demosponges and scleractinians. Corals were still subordinated to sponges. Taxonomic diversity increases greatly and the skeletal component exceeds the 50% of the rock volume

  16. Modular Platforms for Optofluidic Systems

    Science.gov (United States)

    Brammer, Marko; Mappes, Timo

    2014-01-01

    Optofluidics is increasingly gaining impact in a number of different fields of research, namely biology and medicine, environmental monitoring and green energy. However, the market for optofluidic products is still in the early development phase. In this manuscript, we discuss modular platforms as a potential concept to facilitate the transfer of optofluidic sensing systems to an industrial implementation. We present microfluidic and optical networks as a basis for the interconnection of optofluidic sensor modules. Finally, we show the potential for entire optofluidic networks

  17. Platform development: implications for portfolio management

    DEFF Research Database (Denmark)

    Hsuan, Juliana; Hansen, Poul H. Kyvsgård

    2007-01-01

    complex, possibly increasing the strategic risks for the firm. This paper reports preliminary findings on platform management process at LEGO, a Danish toy company. Specifically, we report the process of applying games combined with simulations and workshops in the platform development. We also propose...... a framework, based on the portfolio management thinking to evaluate the degree of modularity embedded in a given platform and to which extent it is aligned with other platforms."...

  18. Electrorheological fluid-actuated flexible platform

    Science.gov (United States)

    Liu, Liyu; Niu, Xize; Wen, Weijia; Sheng, Ping

    2006-04-01

    The design, fabrication, and performance of an electrorheological (ER) fluid-actuated flexible platform integrated on a microfluidic chip are reported in this letter. The digitally regulated ER microvalves control the four diaphragms on which a platform is sustained. With electrical input signals, the platform can perform vibrations at tunable frequencies as well as generate complex leveling modes. The flexible platform can potentially act as a microdamper when its inputs are generated from a sensor, in combination with a feedback control system.

  19. Towards a Framework of Digital Platform Competition

    DEFF Research Database (Denmark)

    Kazan, Erol; Tan, Chee-Wee; Lim, Eric T. K.

    2016-01-01

    This paper advances a framework for examining the competitive principles of mobile payment platforms. We postulate that the strategic interplay of platform layers will drive the competitive dynamics of platform-driven ubiquitous systems. This framework has been employed in a comparative case study...

  20. A Typology of Multi-sided Platforms

    DEFF Research Database (Denmark)

    Staykova, Kalina Stefanova; Damsgaard, Jan

    2015-01-01

    which evolved several steps into being multi-sided (Facebook). Our analysis shows a structural difference between one-sided, two-sided and multi-sided platforms and that platforms consist of a core and potentially also a periphery. The sides of a platform and the ties which connect them can be arranged...

  1. BESIU Physical Analysis on Hadoop Platform

    Science.gov (United States)

    Huo, Jing; Zang, Dongsong; Lei, Xiaofeng; Li, Qiang; Sun, Gongxing

    2014-06-01

    In the past 20 years, computing cluster has been widely used for High Energy Physics data processing. The jobs running on the traditional cluster with a Data-to-Computing structure, have to read large volumes of data via the network to the computing nodes for analysis, thereby making the I/O latency become a bottleneck of the whole system. The new distributed computing technology based on the MapReduce programming model has many advantages, such as high concurrency, high scalability and high fault tolerance, and it can benefit us in dealing with Big Data. This paper brings the idea of using MapReduce model to do BESIII physical analysis, and presents a new data analysis system structure based on Hadoop platform, which not only greatly improve the efficiency of data analysis, but also reduces the cost of system building. Moreover, this paper establishes an event pre-selection system based on the event level metadata(TAGs) database to optimize the data analyzing procedure.

  2. Compartmentalized Platforms for Neuro-Pharmacological Research.

    Science.gov (United States)

    Jadhav, Amol D; Wei, Li; Shi, Peng

    2016-01-01

    Dissociated primary neuronal cell culture remains an indispensable approach for neurobiology research in order to investigate basic mechanisms underlying diverse neuronal functions, drug screening and pharmacological investigation. Compartmentalization, a widely adopted technique since its emergence in 1970s enables spatial segregation of neuronal segments and detailed investigation that is otherwise limited with traditional culture methods. Although these compartmental chambers (e.g. Campenot chamber) have been proven valuable for the investigation of Peripheral Nervous System (PNS) neurons and to some extent within Central Nervous System (CNS) neurons, their utility has remained limited given the arduous manufacturing process, incompatibility with high-resolution optical imaging and limited throughput. The development in the area of microfabrication and microfluidics has enabled creation of next generation compartmentalized devices that are cheap, easy to manufacture, require reduced sample volumes, enable precise control over the cellular microenvironment both spatially as well as temporally, and permit highthroughput testing. In this review we briefly evaluate the various compartmentalization tools used for neurobiological research, and highlight application of the emerging microfluidic platforms towards in vitro single cell neurobiology.

  3. Innovative Mobile Platform Developments for Electronic Services Design and Delivery

    DEFF Research Database (Denmark)

    Scupola, Ada

    In the ever-growing world of technology, it is becoming more important to understand the developments of new electronic services and mobile applications. Innovative Mobile Platform Developments for Electronic Services Design, and Delivery is a comprehensive look at all aspects of production...... management, delivery and consumption of e-services, self services, and mobile communication including business-to-business, business-to-consumer, government-to-business, government-to-consumer, and consumer-to-consumer e-services. This volume is perfect for the interest of professionals, academic educators...

  4. Towards a Framework of Digital Platform Disruption

    DEFF Research Database (Denmark)

    Kazan, Erol; Tan, Chee-Wee; Lim, Eric T. K.

    2014-01-01

    Digital platforms are disruptive information technology (IT) artifacts that erode conventional business logic associated with traditional market structures. This paper presents a framework for examining the disruptive potential of digital platforms whereby we postulate that the strategic interplay...... of governance regimes and platform layers is deterministic of whether disruptive derivatives are permitted to flourish. This framework has been employed in a comparative case study between centralized (i.e., PayPal) and decentralized (i.e., Coinkite) digital payment platforms to illustrate its applicability...... and yield propositions on the nature and impact of digital platform disruptions. Preliminary findings indicate that centralized digital platforms attempt to create unique configurals to obtain monopolistic power by tightly coupling platform layers, which are difficult to replicate. Conversely, decentralized...

  5. Demand forecasting and information platform in tourism

    Science.gov (United States)

    Li, Yue; Jiang, Qi-Jie

    2017-05-01

    Information asymmetry and the bullwhip effect have been serious problems in the tourism supply chain. Based on platform theory, this paper established a mathematical model to explore the inner mechanism of a platform's influence on stakeholders' ability to forecast demand in tourism. Results showed that the variance of stakeholders' demand predictions with a platform was smaller than the variance without a platform, which meant that a platform would improve predictions of demand for stakeholders. The higher information-processing ability of the platform also had other effects on demand forecasting. Research on the inner logic of the platform's influence on stakeholders has important theoretical and realistic value. This area is worthy of further study.

  6. Platform economy in Denmark – precarious employment?

    DEFF Research Database (Denmark)

    Rasmussen, Stine; Madsen, Per Kongshøj

    This paper takes a labour market perspective on the emerging concept of the 'sharing economy' or 'platform economy', which we use as a more appropriate term for the phenomenon. Platform economy is in the article understood as those business models that have emerged since the millennium, where...... digital platforms serve as the link between persons wanting to make use of certain activities, services etc. and those owning them and we only have an interest in the work-related platforms. That means platforms, where paid work is offered and demanded. International examples of this new phenomenon...... of this paper is to examine the work-related activities in the Danish platform economy and discuss whether and to what extent these activities are to be considered precarious forms of employment. The paper begins with a discussion of the terms sharing economy and platform economy in order to reach...

  7. TomoSAR Platform: The New Irstea Service as Demand for SAR, Interferometry, Polarimetry and Tomography

    Science.gov (United States)

    Ho Tong Minh, Dinh; Ngo, Yen-Nhi; Baghdadi, Nicolas; Maurel, Pierre

    2016-08-01

    Developing and improving methods to monitor both natural and non-natural environments such as forest and urban in space and time is a timely challenge. To overcome this challenge, we created a software platform - TomoSAR. The kernel of this platform supports the entire processing from SAR, Interferometry, Polarimetry, to Tomography (so called TomoSAR). The objective of this paper is to introduce this platform about its design architecture and its capacity. We showed four examples to highlight the TomoSAR platform capacities. First, the useful of the interferometric coherence of TOPS Sentinel-1 for land cover classification was highlighted. Second, a TOPS Sentinel-1 differential interferogram in a complex scenario volcano was successfully produced. Third, a TOPS Persistent Scatterers Interferometry analysis for estimating subsidence in Ho Chi Minh City area was demonstrated. Finally, the capability of processing and modelling of 3D P-band tomography in volume forest scattering were reported.

  8. Education Platform at ZDM8.

    Science.gov (United States)

    Lyman Gingerich, Jamie S; Pickart, Michael A; Pierret, Chris

    2016-04-01

    Interest among the zebrafish community in education and science accessibility for all ages has increased. At the 8th Annual Zebrafish Disease Models Conference (ZDM8), a specifically designed session enabled professional scientists, educators, and students to have a venue to present their science, discuss ideas in education, and partner to navigate a scientific meeting as an educational experience. This meeting report describes the format of the Platform Session as well as challenges and future plans to leverage impact of conferences on the local communities.

  9. Generational Transitions in Platform Markets

    DEFF Research Database (Denmark)

    Kretschmer, Tobias; Claussen, Jörg

    2016-01-01

    The introduction of a new product generation forces incumbents in platform markets to rebuild their installed base of complementary products. Using three different data sets on the U.S. market for video game consoles, we show that incumbents can, to some extent, substitute for rebuilding their new...... installed base by making their new products backward compatible, which lets them draw on the installed base of software for the parent generation. However, while this positive direct effect of backward compatibility dominates in our setting, we also observe a (weaker) negative indirect effect working...

  10. Autonomous Landing on Moving Platforms

    KAUST Repository

    Mendoza Chavez, Gilberto

    2016-08-01

    This thesis investigates autonomous landing of a micro air vehicle (MAV) on a nonstationary ground platform. Unmanned aerial vehicles (UAVs) and micro air vehicles (MAVs) are becoming every day more ubiquitous. Nonetheless, many applications still require specialized human pilots or supervisors. Current research is focusing on augmenting the scope of tasks that these vehicles are able to accomplish autonomously. Precise autonomous landing on moving platforms is essential for self-deployment and recovery of MAVs, but it remains a challenging task for both autonomous and piloted vehicles. Model Predictive Control (MPC) is a widely used and effective scheme to control constrained systems. One of its variants, output-feedback tube-based MPC, ensures robust stability for systems with bounded disturbances under system state reconstruction. This thesis proposes a MAV control strategy based on this variant of MPC to perform rapid and precise autonomous landing on moving targets whose nominal (uncommitted) trajectory and velocity are slowly varying. The proposed approach is demonstrated on an experimental setup.

  11. Latex Micro-balloon Pumping in Centrifugal Microfluidic Platforms

    Science.gov (United States)

    Aeinehvand, Mohammad Mahdi; Ibrahim, Fatimah; Al-Faqheri, Wisam; Thio, Tzer Hwai Gilbert; Kazemzadeh, Amin; Wadi harun, Sulaiman; Madou, Marc

    2014-01-01

    Centrifugal microfluidic platforms have emerged as point-of-care diagnostic tools. However, the unidirectional nature of the centrifugal force limits the available space for multi-stepped processes on a single microfluidics disc. To overcome this limitation, a passive pneumatic pumping method actuated at high rotational speeds has been previously proposed to pump liquid against the centrifugal force. In this paper, a novel micro-balloon pumping method that relies on elastic energy stored in a latex membrane is introduced. It operates at low rotational speeds and pumps a larger volume of liquid towards the centre of the disc. Two different micro-balloon pumping designs have been developed to study the pump performance and capacity at a range of rotational frequencies from 0 to 1500 rpm. The behaviour of the micro-balloon pump on the centrifugal microfluidic platforms has been theoretically analysed and compared with the experimental data. The experimental data shows that, the developed pumping method dramatically decreases the required rotational speed to pump liquid compared to the previously developed pneumatic pumping methods. It also shows that within a range of rotational speed, desirable volume of liquid can be stored and pumped by adjusting the size of the micro-balloon. PMID:24441792

  12. Latex micro-balloon pumping in centrifugal microfluidic platforms.

    Science.gov (United States)

    Aeinehvand, Mohammad Mahdi; Ibrahim, Fatimah; Harun, Sulaiman Wadi; Al-Faqheri, Wisam; Thio, Tzer Hwai Gilbert; Kazemzadeh, Amin; Madou, Marc

    2014-03-01

    Centrifugal microfluidic platforms have emerged as point-of-care diagnostic tools. However, the unidirectional nature of the centrifugal force limits the available space for multi-step processes on a single microfluidic disc. To overcome this limitation, a passive pneumatic pumping method actuated at high rotational speeds has been previously proposed to pump liquid against the centrifugal force. In this paper, a novel micro-balloon pumping method that relies on elastic energy stored in a latex membrane is introduced. It operates at low rotational speeds and pumps a larger volume of liquid towards the centre of the disc. Two different micro-balloon pumping mechanisms have been designed to study the pump performance at a range of rotational frequencies from 0 to 1500 rpm. The behaviour of the micro-balloon pump on the centrifugal microfluidic platforms has been theoretically analysed and compared with the experimental data. The experimental data show that the developed pumping method dramatically decreases the required rotational speed to pump liquid compared to the previously developed pneumatic pumping methods. It also shows that within a range of rotational speed, a desirable volume of liquid can be stored and pumped by adjusting the size of the micro-balloon.

  13. Platform development: implications for portfolio management

    DEFF Research Database (Denmark)

    Hsuan, Juliana; Hansen, Poul H. Kyvsgård

    2007-01-01

    " The challenge of implementing industrial platforms in practice can be described as a configuration problem caused by a considerable number of variables, which often have contradictory influences on the total performance of the firm. Consequently, the specific platform decisions become extremely...... a framework, based on the portfolio management thinking to evaluate the degree of modularity embedded in a given platform and to which extent it is aligned with other platforms."...... complex, possibly increasing the strategic risks for the firm. This paper reports preliminary findings on platform management process at LEGO, a Danish toy company. Specifically, we report the process of applying games combined with simulations and workshops in the platform development. We also propose...

  14. Digital platforms as enablers for digital transformation

    DEFF Research Database (Denmark)

    Hossain, Mokter; Lassen, Astrid Heidemann

    2017-01-01

    Digital platforms offer new ways for organizations to collaborate with the external environment for ideas, technologies, and knowledge. They provide new possibilities and competence but they also bring new challenges for organizations. Understanding the role of these platforms in digital...... transformation is crucial. This study aims at exploring how organizations are driven towards transformation in various ways to embrace digital platforms for ideas, technologies, and knowledge. It shows the opportunities and challenges digital platforms bring in organizations. It also highlights underlying...... mechanisms and potential outcomes of various digital platforms. The contribution of the submission is valuable for scholars to understand and further explore this area. It provides insight for practitioners to capture value through digital platforms and accelerate the pace of organizations’ digital...

  15. The Dynamics of Digital Platform Innovation

    DEFF Research Database (Denmark)

    Eaton, Ben

    2016-01-01

    Curated platforms provide an architectural basis for third parties to develop platform complements and for platform owners to control their implementation as a form of open innovation. The refusal to implement complements as innovations can cause tension between platform owners and developers....... The dynamic concerning this control of innovation is not well understood in platform literature. This research attempts to address that gap by using qualitative methods to build narrative networks which analyze 45 examples of contested platform innovation. This approach, informed by empirical data sourced...... from 4664 blogs, identifies patterned sequences of actions describing tussles across the examples. Mechanisms are then identified, which explain how control is asserted and resisted. The principle contribution of this research is to describe and explain the dynamics of contested innovation on curated...

  16. "Movable platform" - the idea and energy consumption

    OpenAIRE

    Czesław PYPNO; Margielewicz, Jerzy; Gąska, Damian

    2011-01-01

    This paper presents the application of the concept of moving sidewalks at railway stations (the movable platform) including the calculation of electricity consumption. Particular focus was placed on issue of energy profit and loss in two stages - through the loss (consumption) of energy by using a moving sidewalk at a railway station platform and the profit (reduced consumption) of energy, by the lack of having to start the train, that supports movable platform, from the initial speed of 0 km/h.

  17. Applied architecture patterns on the Microsoft platform

    CERN Document Server

    Dovgal, Andre; Noriskin, Gregor

    2014-01-01

    Presented in a scenario-driven tutorial way, we lead you through fictitious example problems and present you with the best solutions. This book is intended for architects, developers, and managers who need to improve their knowledge of the Microsoft application platform. This book will appeal to anyone, especially consultants, who want to get up to speed on selecting the most appropriate platform for a particular problem. A good understanding of the general Windows platform and development technologies would be helpful.

  18. Managing Clouds in Cloud Platforms

    CERN Document Server

    Ahmat, Kamal A

    2010-01-01

    Managing cloud services is a fundamental challenge in todays virtualized environments. These challenges equally face both providers and consumers of cloud services. The issue becomes even more challenging in virtualized environments that support mobile clouds. Cloud computing platforms such as Amazon EC2 provide customers with flexible, on demand resources at low cost. However, they fail to provide seamless infrastructure management and monitoring capabilities that many customers may need. For instance, Amazon EC2 doesn't fully support cloud services automated discovery and it requires a private set of authentication credentials. Salesforce.com, on the other hand, do not provide monitoring access to their underlying systems. Moreover, these systems fail to provide infrastructure monitoring of heterogenous and legacy systems that don't support agents. In this work, we explore how to build a cloud management system that combines heterogeneous management of virtual resources with comprehensive management of phys...

  19. Web platform for functional design

    Science.gov (United States)

    Dijmarescu, M. R.; Dijmarescu, M. C.

    2015-11-01

    Today's global competitive trends, especially those related to industries, determine a much higher degree of pressure and demands for substantial innovation driven improvements, flexible and time sensitive solutions. Improving and optimizing the design activity by shortening its timeline and maintaining a high quality level for its output have become the main success factors. The evolution of design activity is strongly related to the evolution of education and research made in the design field. Thus, the development of web tools which can contain knowledge about mechanical products functionality and structure may be an important achievement for the education and industry. This paper presents a web platform which contains functional-constructive knowledge in the area of mechanical design field and was developed to support design activity. The proposed web tool can provide any user, even one without background in design theory, information about the functionality of products and the way it is related to the product structure.

  20. SERS sensors for DVD platform

    DEFF Research Database (Denmark)

    Brøgger, Anna Line

    This Ph.D. thesis explores the engineering of a portable sensor system for detection of rare and small molecules. The Ph.D. project is part of the research project 'Multi-Sensor DVD platform' (MUSE), aiming to integrate different sensors on a rotating disc. The sensors are chosen to complement each...... other, creating more reliable and stable results for the end user. The rotating disc comprises microfluidic channels, which can be utilized for handling and manipulating liquid samples such as blood or water. The focus of this Ph.D. thesis, is on the integration of one specific sensor on a rotating disc....... The sensor is based upon surface enhanced Raman spectroscopy (SERS), which detects molecular vibrations. The aim of this thesis is to cover the different aspects of the sensor system. SERS substrates, consisting of nanopillars with gold or silver caps on top, have been fabricated by standard micro and nano...

  1. Platform for controlled supramolecular nanoassembly.

    Science.gov (United States)

    Czolkos, Ilja; Hannestad, Jonas K; Jesorka, Aldo; Kumar, Ravindra; Brown, Tom; Albinsson, Bo; Orwar, Owe

    2009-06-01

    We here present a two-dimensional (2D) micro/nano-fluidic technique where reactant-doped liquid-crystal films spread and mix on micro- and nanopatterned substrates. Surface-supported phospholipid monolayers are individually doped with complementary DNA molecules which hybridize when these lipid films mix. Using lipid films to convey reactants reduces the dimensionality of traditional 3D chemistry to 2D, and possibly to 1D by confining the lipid film to nanometer-sized lanes. The hybridization event was observed by FRET using single-molecule-sensitive confocal fluorescence detection. We could successfully detect hybridization in lipid streams on 250 nm wide lanes. Our results show that the number and density of reactants as well as sequence of reactant addition can be controlled within confined liquid crystal films, providing a platform for nanochemistry with potential for kinetic control.

  2. Quantum photonics hybrid integration platform

    CERN Document Server

    Murray, Eoin; Meany, Thomas; Flother, Frederick F; Lee, James P; Griffiths, Jonathan P; Jones, Geb A C; Farrer, Ian; Ritchie, David A; Bennet, Anthony J; Shields, Andrew J

    2015-01-01

    Fundamental to integrated photonic quantum computing is an on-chip method for routing and modulating quantum light emission. We demonstrate a hybrid integration platform consisting of arbitrarily designed waveguide circuits and single photon sources. InAs quantum dots (QD) embedded in GaAs are bonded to an SiON waveguide chip such that the QD emission is coupled to the waveguide mode. The waveguides are SiON core embedded in a SiO2 cladding. A tuneable Mach Zehnder modulates the emission between two output ports and can act as a path-encoded qubit preparation device. The single photon nature of the emission was veri?ed by an on-chip Hanbury Brown and Twiss measurement.

  3. Quantum photonics hybrid integration platform

    Energy Technology Data Exchange (ETDEWEB)

    Murray, E.; Floether, F. F. [Cambridge Research Laboratory, Toshiba Research Europe Limited, 208 Science Park, Milton Road, Cambridge CB4 0GZ (United Kingdom); Cavendish Laboratory, University of Cambridge, J.J. Thomson Avenue, Cambridge CB3 0HE (United Kingdom); Ellis, D. J. P.; Meany, T.; Bennett, A. J., E-mail: anthony.bennet@crl.toshiba.co.uk; Shields, A. J. [Cambridge Research Laboratory, Toshiba Research Europe Limited, 208 Science Park, Milton Road, Cambridge CB4 0GZ (United Kingdom); Lee, J. P. [Cambridge Research Laboratory, Toshiba Research Europe Limited, 208 Science Park, Milton Road, Cambridge CB4 0GZ (United Kingdom); Engineering Department, University of Cambridge, 9 J. J. Thomson Avenue, Cambridge CB3 0FA (United Kingdom); Griffiths, J. P.; Jones, G. A. C.; Farrer, I.; Ritchie, D. A. [Cavendish Laboratory, University of Cambridge, J.J. Thomson Avenue, Cambridge CB3 0HE (United Kingdom)

    2015-10-26

    Fundamental to integrated photonic quantum computing is an on-chip method for routing and modulating quantum light emission. We demonstrate a hybrid integration platform consisting of arbitrarily designed waveguide circuits and single-photon sources. InAs quantum dots (QD) embedded in GaAs are bonded to a SiON waveguide chip such that the QD emission is coupled to the waveguide mode. The waveguides are SiON core embedded in a SiO{sub 2} cladding. A tuneable Mach Zehnder interferometer (MZI) modulates the emission between two output ports and can act as a path-encoded qubit preparation device. The single-photon nature of the emission was verified using the on-chip MZI as a beamsplitter in a Hanbury Brown and Twiss measurement.

  4. The mid-IR silicon photonics sensor platform (Conference Presentation)

    Science.gov (United States)

    Kimerling, Lionel; Hu, Juejun; Agarwal, Anuradha M.

    2017-02-01

    Advances in integrated silicon photonics are enabling highly connected sensor networks that offer sensitivity, selectivity and pattern recognition. Cost, performance and the evolution path of the so-called `Internet of Things' will gate the proliferation of these networks. The wavelength spectral range of 3-8um, commonly known as the mid-IR, is critical to specificity for sensors that identify materials by detection of local vibrational modes, reflectivity and thermal emission. For ubiquitous sensing applications in this regime, the sensors must move from premium to commodity level manufacturing volumes and cost. Scaling performance/cost is critically dependent on establishing a minimum set of platform attributes for point, wearable, and physical sensing. Optical sensors are ideal for non-invasive applications. Optical sensor device physics involves evanescent or intra-cavity structures for applied to concentration, interrogation and photo-catalysis functions. The ultimate utility of a platform is dependent on sample delivery/presentation modalities; system reset, recalibration and maintenance capabilities; and sensitivity and selectivity performance. The attributes and performance of a unified Glass-on-Silicon platform has shown good prospects for heterogeneous integration on materials and devices using a low cost process flow. Integrated, single mode, silicon photonic platforms offer significant performance and cost advantages, but they require discovery and qualification of new materials and process integration schemes for the mid-IR. Waveguide integrated light sources based on rare earth dopants and Ge-pumped frequency combs have promise. Optical resonators and waveguide spirals can enhance sensitivity. PbTe materials are among the best choices for a standard, waveguide integrated photodetector. Chalcogenide glasses are capable of transmitting mid-IR signals with high transparency. Integrated sensor case studies of i) high sensitivity analyte detection in

  5. An Investigation of Digital Payment Platform Designs

    DEFF Research Database (Denmark)

    Kazan, Erol; Damsgaard, Jan

    2014-01-01

    platforms that combines platform, technology and business design aspects. The framework is applied to conduct a comparative case study of digital payment platforms. Four types of market actors are considered: banks, mobile network operators, merchants, and startups, which are incumbents and disrupters....... By hosting third-party services, payment instruments are evolving from single-purpose to multi-functional ones. Our research extends existing payment literature from the MSP perspective to emphasize certain digital payment platform components, which impact strategies and complementary products....

  6. Material platforms for integrated quantum photonics

    CERN Document Server

    Bogdanov, Simeon; Boltasseva, Alexandra; Shalaev, Vladimir M

    2016-01-01

    On-chip integration of quantum optical systems could be a major factor enabling photonic quantum technologies. Unlike the case of electronics, where the essential device is a transistor and the dominant material is silicon, the toolbox of elementary devices required for both classical and quantum photonic integrated circuits is vast. Therefore, many material platforms are being examined to host the future quantum photonic computers and network nodes. We discuss the pros and cons of several platforms for realizing various elementary devices, compare the current degrees of integration achieved in each platform and review several composite platform approaches.

  7. The Innovative Capabilities Of Digital Payment Platforms

    DEFF Research Database (Denmark)

    Kazan, Erol

    2015-01-01

    the support for open innovation. The proposed model has been employed in a comparative case study between two digital payment platforms: Apple Pay and Google Wallet. The findings suggest that digital payment platforms make use of boundary resources to be highly integrative or integratable, which supports...... the intended conjoint commercialization efforts. Furthermore, the architectural design of digital platforms impacts the access to commercialization, resulting to an exclusion or inclusion strategy in accessing value opportunities. Our findings contribute to the open innovation and digital platform literature...

  8. Printable Spacecraft: Flexible Electronic Platforms for NASA Missions. Phase One

    Science.gov (United States)

    Short, Kendra (Principal Investigator); Van Buren, David (Principal Investigator)

    2012-01-01

    Atmospheric confetti. Inchworm crawlers. Blankets of ground penetrating radar. These are some of the unique mission concepts which could be enabled by a printable spacecraft. Printed electronics technology offers enormous potential to transform the way NASA builds spacecraft. A printed spacecraft's low mass, volume and cost offer dramatic potential impacts to many missions. Network missions could increase from a few discrete measurements to tens of thousands of platforms improving areal density and system reliability. Printed platforms could be added to any prime mission as a low-cost, minimum resource secondary payload to augment the science return. For a small fraction of the mass and cost of a traditional lander, a Europa flagship mission might carry experimental printed surface platforms. An Enceladus Explorer could carry feather-light printed platforms to release into volcanic plumes to measure composition and impact energies. The ability to print circuits directly onto a variety of surfaces, opens the possibility of multi-functional structures and membranes such as "smart" solar sails and balloons. The inherent flexibility of a printed platform allows for in-situ re-configurability for aerodynamic control or mobility. Engineering telemetry of wheel/soil interactions are possible with a conformal printed sensor tape fit around a rover wheel. Environmental time history within a sample return canister could be recorded with a printed sensor array that fits flush to the interior of the canister. Phase One of the NIAC task entitled "Printable Spacecraft" investigated the viability of printed electronics technologies for creating multi-functional spacecraft platforms. Mission concepts and architectures that could be enhanced or enabled with this technology were explored. This final report captures the results and conclusions of the Phase One study. First, the report presents the approach taken in conducting the study and a mapping of results against the proposed

  9. Ovarian volume throughout life

    DEFF Research Database (Denmark)

    Kelsey, Thomas W; Dodwell, Sarah K; Wilkinson, A Graham

    2013-01-01

    cancer. To date there is no normative model of ovarian volume throughout life. By searching the published literature for ovarian volume in healthy females, and using our own data from multiple sources (combined n=59,994) we have generated and robustly validated the first model of ovarian volume from...... to about 2.8 mL (95% CI 2.7-2.9 mL) at the menopause and smaller volumes thereafter. Our model allows us to generate normal values and ranges for ovarian volume throughout life. This is the first validated normative model of ovarian volume from conception to old age; it will be of use in the diagnosis...

  10. Market projections of cellulose nanomaterial-enabled products-- Part 2: Volume estimates

    Science.gov (United States)

    John Cowie; E.M. (Ted) Bilek; Theodore H. Wegner; Jo Anne Shatkin

    2014-01-01

    Nanocellulose has enormous potential to provide an important materials platform in numerous product sectors. This study builds on previous work by the same authors in which likely high-volume, low-volume, and novel applications for cellulosic nanomaterials were identified. In particular, this study creates a transparent methodology and estimates the potential annual...

  11. Offshore Wind Park Connection to an HVDC Platform, without using an AC Collector Platform

    OpenAIRE

    Ahmad, Haseeb

    2012-01-01

    This thesis investigates the comparison between two different alternating current topologies of an offshore wind farms connection to an offshore high voltage direct current (HVDC) converter platform. The offshore high voltage direct current converter platform converts alternating current into direct current. Two different topologies will be investigated. In the first topology, the offshore wind farms are connected to an HVDC converter platform through offshore AC collector platform. An offsho...

  12. A novel 120dB hyperspectral platform for Earth observation

    Science.gov (United States)

    Dupont, B.; Caranana, J.; Pinoncely, P. A.; Michelot, J.; Bouvier, C.; Cohet, S.; Jourdain, P.; Monsinjon, P.; Le-Coarer, E.

    2016-10-01

    With the down-size of spacecraft for earth observation in volume, power and budget, there is a pressing need for new, more affordable, easier to integrate, instrumentation sensor. Pyxalis has developed a high dynamic range image sensor dedicated to hyperspectral imaging. This platform can be customized for space or ground-based application, reducing significantly the need for a full-custom detector development for space application. This work describes the development and characterization of such a 120dB High Dynamic Range sensor platform as well as the various possibilities for customization as well as a particular implementation by Grenoble University in the Context of a micro-satellite development.

  13. 77 FR 20558 - Federal Motor Vehicle Safety Standards; Platform Lifts for Motor Vehicles; Platform Lift...

    Science.gov (United States)

    2012-04-05

    ... National Highway Traffic Safety Administration 49 CFR Part 571 RIN 2127-AJ93 Federal Motor Vehicle Safety Standards; Platform Lifts for Motor Vehicles; Platform Lift Installations in Motor Vehicles AGENCY: National.... SUMMARY: This document adopts amendments to the Federal motor vehicle safety standards on platform...

  14. Mean nuclear volume

    DEFF Research Database (Denmark)

    Mogensen, O.; Sørensen, Flemming Brandt; Bichel, P.

    1999-01-01

    We evaluated the following nine parameters with respect to their prognostic value in females with endometrial cancer: four stereologic parameters [mean nuclear volume (MNV), nuclear volume fraction, nuclear index and mitotic index], the immunohistochemical expression of cancer antigen (CA125...

  15. Efficient High Performance Computing on Heterogeneous Platforms

    NARCIS (Netherlands)

    Shen, J.

    2015-01-01

    Heterogeneous platforms are mixes of different processing units in a compute node (e.g., CPUs+GPUs, CPU+MICs) or a chip package (e.g., APUs). This type of platforms keeps gaining popularity in various computer systems ranging from supercomputers to mobile devices. In this context, improving their

  16. MCloud platform - common government informational infrastructure

    Directory of Open Access Journals (Sweden)

    Eugenia CEBOTARU

    2017-03-01

    Full Text Available MCloud platform is foreseen for the exclusive use by the central administrative authorities and organizational structures within their jurisdiction, subordinated to the Government and is an innovative delivery model based on infrastructure consumption, platform and software as services

  17. Efficient High Performance Computing on Heterogeneous Platforms

    NARCIS (Netherlands)

    Shen, J.

    2015-01-01

    Heterogeneous platforms are mixes of different processing units in a compute node (e.g., CPUs+GPUs, CPU+MICs) or a chip package (e.g., APUs). This type of platforms keeps gaining popularity in various computer systems ranging from supercomputers to mobile devices. In this context, improving their ef

  18. Platform Expansion Design as Strategic Choice

    DEFF Research Database (Denmark)

    Staykova, Kalina S.; Damsgaard, Jan

    2016-01-01

    the main characteristics of the two approaches and to identify the potential trade-offs associated with the selection of particular expansion mode. To this end, we construct the Platform Strategy Framework and apply it to two exemplary cases – WeChat, which functions as a feature bundling platform...

  19. Reflection on Foreign Languages Network Teaching Platform

    Institute of Scientific and Technical Information of China (English)

    LIANG Yuan

    2014-01-01

    This paper aims to build awareness in applying foreign languages network teaching platform to higher education. Teachers rationally use foreign languages network teaching platform to hold an initiative concept, establish a cooperative and in-teractive learning atmosphere, and a prompt and dynamic assessment system.

  20. Maximal workload capacity on moving platforms

    NARCIS (Netherlands)

    Heus, R.; Wertheim, A.H.

    1996-01-01

    Physical tasks on a moving platform required more energy than the same tasks on a non-moving platform. In this study the maximum aerobic performance (defined as V_O2max) of people working on a moving floor was established compared to the maximal aerobic performance on a non-moving floor. The main

  1. Maximal workload capacity on moving platforms

    NARCIS (Netherlands)

    Heus, R.; Wertheim, A.H.

    1996-01-01

    Physical tasks on a moving platform required more energy than the same tasks on a non-moving platform. In this study the maximum aerobic performance (defined as V_O2max) of people working on a moving floor was established compared to the maximal aerobic performance on a non-moving floor. The main qu

  2. PLATFORM SETS FIVE-YEAR GOALS

    Institute of Scientific and Technical Information of China (English)

    1996-01-01

    THE 100,000-word Platform for Action adopted on September 15, 1995, at the UN Fourth World Conference on Women in Beijing, includes six chapters of more than 300 paragraphs. The Platform reviews and evaluates the progress of women since the adoption of the "Nairobi Forward-Looking

  3. A Simulation Platform for Localization and Mapping

    DEFF Research Database (Denmark)

    Sejerøe, Thomas Hanefeld; Poulsen, Niels Kjølstad; Ravn, Ole

    2006-01-01

    In this paper we present a simulation platform for evaluate methods for simultaneous location and mapping. The platform is based on The Kalmtool 3 toolbox which is a set of MATLAB tools for state estimation for nonlinear systems. The toolbox contains functions for extended Kalman filtering as wel...

  4. Selecting a Virtual World Platform for Learning

    Science.gov (United States)

    Robbins, Russell W.; Butler, Brian S.

    2009-01-01

    Like any infrastructure technology, Virtual World (VW) platforms provide affordances that facilitate some activities and hinder others. Although it is theoretically possible for a VW platform to support all types of activities, designers make choices that lead technologies to be more or less suited for different learning objectives. Virtual World…

  5. The Innovative Capabilities Of Digital Payment Platforms

    DEFF Research Database (Denmark)

    Kazan, Erol

    2015-01-01

    the support for open innovation. The proposed model has been employed in a comparative case study between two digital payment platforms: Apple Pay and Google Wallet. The findings suggest that digital payment platforms make use of boundary resources to be highly integrative or integratable, which supports...

  6. Platform Expansion Design as Strategic Choice

    DEFF Research Database (Denmark)

    Staykova, Kalina S.; Damsgaard, Jan

    2016-01-01

    the main characteristics of the two approaches and to identify the potential trade-offs associated with the selection of particular expansion mode. To this end, we construct the Platform Strategy Framework and apply it to two exemplary cases – WeChat, which functions as a feature bundling platform...

  7. Venus Atmospheric Maneuverable Platform (VAMP)

    Science.gov (United States)

    Polidan, R.; Lee, G.; Sokol, D.; Griffin, K.; Bolisay, L.; Barnes, N.

    2014-04-01

    Over the past years we have explored a possible new approach to Venus upper atmosphere exploration by applying recent Northrop Grumman (non-NASA) development programs to the challenges associated with Venus upper atmosphere science missions. Our concept is a low ballistic coefficient (aircraft that deploys prior to entering the Venus atmosphere, enters the Venus atmosphere without an aeroshell, and provides a long-lived (months to years), maneuverable vehicle capable of carrying science payloads to explore the Venus upper atmosphere. VAMP targets the global Venus atmosphere between 55 and 70 km altitude and would be a platform to address VEXAG goals I.A, I.B, and I.C. We will discuss the overall mission architecture and concept of operations from launch through Venus arrival, orbit, entry, and atmospheric science operations. We will present a strawman concept of VAMP, including ballistic coefficient, planform area, percent buoyancy, inflation gas, wing span, vehicle mass, power supply, propulsion, materials considerations, structural elements, subsystems, and packaging. The interaction between the VAMP vehicle and the supporting orbiter will also be discussed. In this context, we will specifically focus upon four key factors impacting the design and performance of VAMP: 1. Science payload accommodation, constraints, and opportunities 2. Characteristics of flight operations and performance in the Venus atmosphere: altitude range, latitude and longitude access, day/night performance, aircraft performance, performance sensitivity to payload weight 3. Feasibility of and options for the deployment of the vehicle in space 4. Entry into the Venus atmosphere, including descent profile, heat rate, total heat load, stagnation temperature, control, and entry into level flight We will discuss interdependencies of the above factors and the manner in which the VAMP strawman's characteristics affect the CONOPs and the science objectives. We will show how the these factors provide

  8. Analysis of scalability of high-performance 3D image processing platform for virtual colonoscopy.

    Science.gov (United States)

    Yoshida, Hiroyuki; Wu, Yin; Cai, Wenli

    2014-03-19

    One of the key challenges in three-dimensional (3D) medical imaging is to enable the fast turn-around time, which is often required for interactive or real-time response. This inevitably requires not only high computational power but also high memory bandwidth due to the massive amount of data that need to be processed. For this purpose, we previously developed a software platform for high-performance 3D medical image processing, called HPC 3D-MIP platform, which employs increasingly available and affordable commodity computing systems such as the multicore, cluster, and cloud computing systems. To achieve scalable high-performance computing, the platform employed size-adaptive, distributable block volumes as a core data structure for efficient parallelization of a wide range of 3D-MIP algorithms, supported task scheduling for efficient load distribution and balancing, and consisted of a layered parallel software libraries that allow image processing applications to share the common functionalities. We evaluated the performance of the HPC 3D-MIP platform by applying it to computationally intensive processes in virtual colonoscopy. Experimental results showed a 12-fold performance improvement on a workstation with 12-core CPUs over the original sequential implementation of the processes, indicating the efficiency of the platform. Analysis of performance scalability based on the Amdahl's law for symmetric multicore chips showed the potential of a high performance scalability of the HPC 3D-MIP platform when a larger number of cores is available.

  9. Reinventing the Platform Core Through Acquisition

    DEFF Research Database (Denmark)

    Toppenberg, Gustav; Henningsson, Stefan; Eaton, Ben

    2016-01-01

    Digital platform leaders need to continuously innovate the platform core to drive the technological trajectory of the overall architecture and business system, of which the platform is a core element. This papers analyses the potential of and challenges to completing this task through...... the acquisition and integration of companies presenting innovative technologies of relevance to the platform core. Using a revelatory case study of Cisco Systems, we develop the explanatory notion of ‘coring acquisition’. In this type of acquisition value is created through the acquisition of companies...... that provide products external to the acquirer that can be assimilated into the platform core. This creates value through the transformational process that we term ‘coring’. We also analyze how the benefits of coring acquisitions are contingent on challenges concerning the integration of acquisitions offering...

  10. Peer-to-Peer Service Sharing Platforms

    DEFF Research Database (Denmark)

    Andersson, Magnus; Hjalmarsson, Anders; Avital, Michel

    2013-01-01

    The sharing economy has been growing continuously in the last decade thanks to the proliferation of internet-based platforms that allow people to disintermediate the traditional commercial channels and to share excess resources and trade with one another effectively at a reasonably low transaction...... cost. Whereas early peer-to-peer platforms were designed to enable file sharing and goods trading, we recently witness the emergence of a new breed of peer-to-peer platforms that are designed for ordinary service sharing. Ordinary services entail intangible provisions and are defined as an economic...... activity that generates immaterial benefits and does not result in ownership of material goods. Based on a structured analysis of 41 internet-based rideshare platforms, we explore and layout the unique characteristics of peer-to-peer service sharing platforms based on three distinct temporal patterns...

  11. ENERCA: e-learning platform

    Directory of Open Access Journals (Sweden)

    Patricia Aguilar-Martínez

    2014-12-01

    Full Text Available ENERCA (the European Network for Rare and Congenital Anemias is a European Commission funded project since 2002. Rare anaemias in Europe comprise haemoglobin disorders, such as thalassemias or sickle cell disease, and other rarer disorders, including inherited diseases of the red cell membrane, of the red cell enzymes, as well as anaemias related to disorders of iron metabolism. Education and training on rare anaemias is one of the main objectives of ENERCA and several educational initiatives have been undertaken during the past and present phases of the project. Among these, the organisation of courses for health professionals, the provision of videos with prevention messages for patients and general practitioners were part of the previous phase, ENERCA 3. In the current phase of the ENERCA project, called e-ENERCA, the workpackage dedicated to Education and Training mainly focuses on training of young physicians, biologists or scientists in the field of diagnosis and management of rare anaemias. The specificity of e-ENERCA is to be based principally on new communication e-tool. Two main educational axes will be developed: the organisation of on-site courses including interactive sessions with voting boxes and the implementation of an online e-learning platform.

  12. Basin Assessment Spatial Planning Platform

    Energy Technology Data Exchange (ETDEWEB)

    2017-07-26

    The tool is intended to facilitate hydropower development and water resource planning by improving synthesis and interpretation of disparate spatial datasets that are considered in development actions (e.g., hydrological characteristics, environmentally and culturally sensitive areas, existing or proposed water power resources, climate-informed forecasts). The tool enables this capability by providing a unique framework for assimilating, relating, summarizing, and visualizing disparate spatial data through the use of spatial aggregation techniques, relational geodatabase platforms, and an interactive web-based Geographic Information Systems (GIS). Data are aggregated and related based on shared intersections with a common spatial unit; in this case, industry-standard hydrologic drainage areas for the U.S. (National Hydrography Dataset) are used as the spatial unit to associate planning data. This process is performed using all available scalar delineations of drainage areas (i.e., region, sub-region, basin, sub-basin, watershed, sub-watershed, catchment) to create spatially hierarchical relationships among planning data and drainages. These entity-relationships are stored in a relational geodatabase that provides back-end structure to the web GIS and its widgets. The full technology stack was built using all open-source software in modern programming languages. Interactive widgets that function within the viewport are also compatible with all modern browsers.

  13. The ideal hydrogen demonstration platform

    Energy Technology Data Exchange (ETDEWEB)

    Alt, J. [Village Technology, Annapolis, MD (United States)

    2007-07-01

    This paper suggested that the best platform to demonstrate hydrogen's capability as an emission-free fuel regime is an urban pedestrian system. The on-grade bi-directional downtown people-mover was designed to fit in existing street-scapes without eliminating traffic lanes. The system is comprised of rubber-tired tram-buses that are synchronized to arrive at stop-boarding areas at the same time in order to provide a seamless headway along a single, dedicated guide-lane. The system was designed to operate along strategic urban corridors in order to reduce traffic congestion and air pollution. The vehicles are inductively charged with fixed fuel cell generators at stop-boarding areas. A single people-mover has the capacity to replace several thousand car trips and parking movements per day, or 8000 tonnes of carbon dioxide (CO{sub 2}). It was concluded that the system was designed to dovetail with fuel cell generator stations planned for private vehicles as they begin to be converted in the future. 8 figs.

  14. Comparison of Hybrid Cross-Platform Mobile Applications with Native Cross-Platform Applications

    Directory of Open Access Journals (Sweden)

    NOVAC Ovidiu Constantin

    2016-10-01

    Full Text Available In this paper we present two types of cross platform mobile applications, we will look at the advantages and disadvantages of each one. Hybrid applications are HTML5/Javascript applications which are given a native device wrapper in order to be able to run as a stand-alone application, rather than a web page which has to be rendered in the web browser. These types of application look the same on each platform they are deployed to. Native cross platform applications offers platform-like styling, making almost impossible to tell the difference between a native and a cross platform application.

  15. Highly sensitive and multiplexed platforms for allergy diagnostics

    Science.gov (United States)

    Monroe, Margo R.

    Allergy is a disorder of the immune system caused by an immune response to otherwise harmless environmental allergens. Currently 20% of the US population is allergic and 90% of pediatric patients and 60% of adult patients with asthma have allergies. These percentages have increased by 18.5% in the past decade, with predicted similar trends for the future. Here we design sensitive, multiplexed platforms to detect allergen-specific IgE using the Interferometric Reflectance Imaging Sensor (IRIS) for various clinical settings. A microarray platform for allergy diagnosis allows for testing of specific IgE sensitivity to a multitude of allergens, while requiring only small volumes of patient blood sample. However, conventional fluorescent microarray technology is limited by i) the variation of probe immobilization, which hinders the ability to make quantitative, assertive, and statistically relevant conclusions necessary in immunodiagnostics and ii) the use of fluorophore labels, which is not suitable for some clinical applications due to the tendency of fluorophores to stick to blood particulates and require daily calibration methods. This calibrated fluorescence enhancement (CaFE) method integrates the low magnification modality of IRIS with enhanced fluorescence sensing in order to directly correlate immobilized probe (major allergens) density to allergen-specific IgE in patient serum. However, this platform only operates in processed serum samples, which is not ideal for point of care testing. Thus, a high magnification modality of IRIS was adapted as an alternative allergy diagnostic platform to automatically discriminate and size single nanoparticles bound to specific IgE in unprocessed, characterized human blood and serum samples. These features make IRIS an ideal candidate for clinical and diagnostic applications, such a POC testing. The high magnification (nanoparticle counting) modality in conjunction with low magnification of IRIS in a combined instrument

  16. Reliability of plantar pressure platforms.

    Science.gov (United States)

    Hafer, Jocelyn F; Lenhoff, Mark W; Song, Jinsup; Jordan, Joanne M; Hannan, Marian T; Hillstrom, Howard J

    2013-07-01

    Plantar pressure measurement is common practice in many research and clinical protocols. While the accuracy of some plantar pressure measuring devices and methods for ensuring consistency in data collection on plantar pressure measuring devices have been reported, the reliability of different devices when testing the same individuals is not known. This study calculated intra-mat, intra-manufacturer, and inter-manufacturer reliability of plantar pressure parameters as well as the number of plantar pressure trials needed to reach a stable estimate of the mean for an individual. Twenty-two healthy adults completed ten walking trials across each of two Novel emed-x(®) and two Tekscan MatScan(®) plantar pressure measuring devices in a single visit. Intraclass correlation (ICC) was used to describe the agreement between values measured by different devices. All intra-platform reliability correlations were greater than 0.70. All inter-emed-x(®) reliability correlations were greater than 0.70. Inter-MatScan(®) reliability correlations were greater than 0.70 in 31 and 52 of 56 parameters when looking at a 10-trial average and a 5-trial average, respectively. Inter-manufacturer reliability including all four devices was greater than 0.70 for 52 and 56 of 56 parameters when looking at a 10-trial average and a 5-trial average, respectively. All parameters reached a value within 90% of an unbiased estimate of the mean within five trials. Overall, reliability results are encouraging for investigators and clinicians who may have plantar pressure data sets that include data collected on different devices.

  17. A thin silicon thermoelectric nanowire characterization platform (TNCP) equipped with nanoporous electrodes for electrical contact formation

    Science.gov (United States)

    Hoda Moosavi, S.; Kroener, Michael; Frei, Maxi; Frick, Fabian; Kerzenmacher, Sven; Woias, Peter

    2016-10-01

    We report on the fabrication of a silicon platform for the thermoelectric and structural characterization of single nanowires, equipped with nanoporous electrodes. Controlled wafer thinning to a thickness of 160 μm results in platform chips, which can be inserted into Transmission Electron Microscopes (TEM) for the nanowire's structural composition analysis. Our fabrication approach comprises the Bosch process (ICP), and "dicing before grinding" techniques to achieve this small thickness. To study the idea of developing a “plug-and-measure” platform, we have developed a novel approach for selfadhesion between a contact electrode and a nanowire by nanoporous electrodes. Due to the increased surface-to-volume ratio and increased van-der-Walls forces nanowires stick firmly to the electrodes for a good thermal and electrical connection. This innovative technique does also avoids, in best case, separate steps for contact formation.

  18. Review: Katja Bett & Joachim Wedekind (Eds. (2003. Lernplattformen in der Praxis [Learning Platforms in Practice

    Directory of Open Access Journals (Sweden)

    Anja Kassel

    2004-01-01

    Full Text Available This volume documents 13 contributions to workshop discussions on "Learning Platforms in Practice" which were held at the "Institut für Wissensmedien" in 2002 (http://www.iwm-kmrc.de/kevih/workshops/. It addresses university faculty who would like to offer (at least in part teaching via virtual learning platforms. The emphases lie in particular with teaching and learning-related issues. These include practical experiences with the use of learning platforms, standardization and quality criteria, and last, but not least, decision-making processes, general conditions, and the future of the e-learning scene. These single contributions are illustrated by screenshots, graphics, literature, and website references. Some contributions, however, assume a deeper technical knowledge. URN: urn:nbn:de:0114-fqs0401332

  19. Nanotag-enabled photonic crystal fiber as quantitative surface-enhanced Raman scattering optofluidic platform

    Energy Technology Data Exchange (ETDEWEB)

    Pinkhasova, Polina; Chen, Hui; Du, Henry, E-mail: hdu@stevens.edu [Department of Chemical Engineering and Materials Science, Stevens Institute of Technology, Hoboken, New Jersey 07030 (United States); Kanka, Jiri [Institute of Photonics and Electronics, Academy of Sciences of the Czech Republic, Chaberska 57, 182 31 Prague (Czech Republic); Mergo, Pawel [Department of Optical Fibres Technology, Maria Curie-Sklodovska University, PI. M. Currie-Sklodowskiej 5, 20-031 Lublin (Poland)

    2015-02-16

    Core-shell nanotags that are active in surface-enhanced Raman scattering (SERS) and entrapped with thiocyanate (SCN) label molecules were immobilized in the air channels of suspended-core photonic crystal fiber (PCF) to impart quantitative capacity to SERS-based PCF optofluidic sensing platform. The Raman intensity of Rhodamine 6G increases with concentration, whereas the intensity of SCN remains constant when measured using this platform. The signal from the SCN label can be used as an internal reference to establish calibration for quantitative measurements of analytes of unknown concentrations. The long optical path-length PCF optofluidic platform integrated with SERS-active core-shell nanotags holds significant promise for sensitive quantitative chem/bio measurements with the added benefit of small sampling volume. The dependence of SERS intensity on the nanotag coverage density and PCF length was interpreted based on numerical-analytical simulations.

  20. A Multichannel Bioluminescence Determination Platform for Bioassays.

    Science.gov (United States)

    Kim, Sung-Bae; Naganawa, Ryuichi

    2016-01-01

    The present protocol introduces a multichannel bioluminescence determination platform allowing a high sample throughput determination of weak bioluminescence with reduced standard deviations. The platform is designed to carry a multichannel conveyer, an optical filter, and a mirror cap. The platform enables us to near-simultaneously determine ligands in multiple samples without the replacement of the sample tubes. Furthermore, the optical filters beneath the multichannel conveyer are designed to easily discriminate colors during assays. This optical system provides excellent time- and labor-efficiency to users during bioassays.

  1. CORBA Based Information Integration Platform for CIMS

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    A new information integration platform for computer integrated manufacturing system(CIMS) is presented, which is based on agent and CORBA. CORBA enhances the system integration be-cause it is an industry-standard for interoperable, distributed objects across heterogeneous hardware andsoftware platform. Agent technology is used to improve intelligence of integration system. In order to im-plement the information integration platform, we use network integration server to integrate network, de-sign a generic database agent to integrate database, adopt multi-agent based architecture to integrate appli-cation, and utilize wrapper as CORBA object to integrate legacy code.

  2. Design for game based learning platforms

    DEFF Research Database (Denmark)

    Sørensen, Birgitte Holm; Meyer, Bente

    2010-01-01

    Council for Strategic Research, in which an online game-based platform for English as a foreign language in primary school is studied. The paper presents a model for designing for game based learning platforms. This design is based on cultural and ethnographic based research on children's leisure time use......This paper focuses on the challenges related to the design of game based learning platforms for formal learning contexts that are inspired by the pupil's leisure time related use of web 2.0. The paper is based on the project Serious Games on a Global Market Place (2007-2011) founded by the Danish...

  3. Secure smart embedded devices, platforms and applications

    CERN Document Server

    Markantonakis, Konstantinos

    2013-01-01

    New generations of IT users are increasingly abstracted from the underlying devices and platforms that provide and safeguard their services. As a result they may have little awareness that they are critically dependent on the embedded security devices that are becoming pervasive in daily modern life. Secure Smart Embedded Devices, Platforms and Applications provides a broad overview of the many security and practical issues of embedded devices, tokens, and their operation systems, platforms and main applications. It also addresses a diverse range of industry/government initiatives and consider

  4. Genesis and Evolution of Digital Payment Platforms

    DEFF Research Database (Denmark)

    Hjelholt, Morten; Damsgaard, Jan

    2012-01-01

    Payment transactions through the use of physical coins, bank notes or credit cards have for centuries been the standard formats of exchanging money. Recently online and mobile digital payment platforms has entered the stage as contenders to this position and possibly could penetrate societies...... applies a co-evolutionary multilevel perspective to model the interplay and processes between technology and society wherein digital payment platforms potentially will substitute other payment platforms just like the credit card negated the check. On this basis this paper formulate a multilevel conceptual...

  5. THE NEED FOR FUNCTION PLATFORMS IN ENGINEER TO ORDER INDUSTRIES

    NARCIS (Netherlands)

    Alblas, Alex; Wortmann, Hans; Bergendahl, MN; Grimheden, M; Leifer, L; Skogstad, P; Cantamessa, M

    2009-01-01

    Many industries base their innovations on product platforms. Platforms have predefined modularity with standardized interfaces. However, product platforms provide significant challenges to engineering industries that rely heavily on R&D, such as microlithography systems. Developing these systems dep

  6. THE NEED FOR FUNCTION PLATFORMS IN ENGINEER TO ORDER INDUSTRIES

    NARCIS (Netherlands)

    Alblas, Alex; Wortmann, Hans; Bergendahl, MN; Grimheden, M; Leifer, L; Skogstad, P; Cantamessa, M

    2009-01-01

    Many industries base their innovations on product platforms. Platforms have predefined modularity with standardized interfaces. However, product platforms provide significant challenges to engineering industries that rely heavily on R&D, such as microlithography systems. Developing these systems dep

  7. THE NEED FOR FUNCTION PLATFORMS IN ENGINEER TO ORDER INDUSTRIES

    NARCIS (Netherlands)

    Alblas, Alex; Wortmann, Hans; Bergendahl, MN; Grimheden, M; Leifer, L; Skogstad, P; Cantamessa, M

    2009-01-01

    Many industries base their innovations on product platforms. Platforms have predefined modularity with standardized interfaces. However, product platforms provide significant challenges to engineering industries that rely heavily on R&D, such as microlithography systems. Developing these systems

  8. Progress on CBET Platform at the Nike Laser

    Science.gov (United States)

    Weaver, J. L.; McKenty, P.; Oh, J.; Kehne, D.; Schmitt, A. J.; Obenschain, S.; Serlin, V.; Lehmberg, R.; Tsung, F.

    2015-11-01

    Cross-beam energy transport (CBET) studies are underway at the Nike krypton-fluoride (KrF) laser at NRL. This facility has unique characteristics that provide an excellent platform for CBET work - including short wavelength (248 nm), large bandwidth (1-3 THz), beam smoothing by induced spatial incoherence (ISI), and full aperture focal spot zooming. Nike's two beam arrays are widely separated (135° in azimuth) which facilitates CBET studies in a nearly opposing geometry, relevant to Polar Direct Drive implosions. Various target types are planned: planar slabs, cylindrical and spherical shells, and low-density targets. The solid targets will be used to examine gradient geometries and the latter will access larger volume, more uniform plasmas. The initial campaign is exploring changes observed by scattered light diagnostics for both beam arrays as the probe laser spectrum is modified. Work supported by DoE/NNSA.

  9. Mapping flow distortion on oceanographic platforms using computational fluid dynamics

    Directory of Open Access Journals (Sweden)

    N. O'Sullivan

    2013-10-01

    Full Text Available Wind speed measurements over the ocean on ships or buoys are affected by flow distortion from the platform and by the anemometer itself. This can lead to errors in direct measurements and the derived parametrisations. Here we computational fluid dynamics (CFD to simulate the errors in wind speed measurements caused by flow distortion on the RV Celtic Explorer. Numerical measurements were obtained from the finite-volume CFD code OpenFOAM, which was used to simulate the velocity fields. This was done over a range of orientations in the test domain from −60 to +60° in increments of 10°. The simulation was also set up for a range of velocities, ranging from 5 to 25 m s−1 in increments of 0.5 m s−1. The numerical analysis showed close agreement to experimental measurements.

  10. A robust robotic high-throughput antibody purification platform.

    Science.gov (United States)

    Schmidt, Peter M; Abdo, Michael; Butcher, Rebecca E; Yap, Min-Yin; Scotney, Pierre D; Ramunno, Melanie L; Martin-Roussety, Genevieve; Owczarek, Catherine; Hardy, Matthew P; Chen, Chao-Guang; Fabri, Louis J

    2016-07-15

    Monoclonal antibodies (mAbs) have become the fastest growing segment in the drug market with annual sales of more than 40 billion US$ in 2013. The selection of lead candidate molecules involves the generation of large repertoires of antibodies from which to choose a final therapeutic candidate. Improvements in the ability to rapidly produce and purify many antibodies in sufficient quantities reduces the lead time for selection which ultimately impacts on the speed with which an antibody may transition through the research stage and into product development. Miniaturization and automation of chromatography using micro columns (RoboColumns(®) from Atoll GmbH) coupled to an automated liquid handling instrument (ALH; Freedom EVO(®) from Tecan) has been a successful approach to establish high throughput process development platforms. Recent advances in transient gene expression (TGE) using the high-titre Expi293F™ system have enabled recombinant mAb titres of greater than 500mg/L. These relatively high protein titres reduce the volume required to generate several milligrams of individual antibodies for initial biochemical and biological downstream assays, making TGE in the Expi293F™ system ideally suited to high throughput chromatography on an ALH. The present publication describes a novel platform for purifying Expi293F™-expressed recombinant mAbs directly from cell-free culture supernatant on a Perkin Elmer JANUS-VariSpan ALH equipped with a plate shuttle device. The purification platform allows automated 2-step purification (Protein A-desalting/size exclusion chromatography) of several hundred mAbs per week. The new robotic method can purify mAbs with high recovery (>90%) at sub-milligram level with yields of up to 2mg from 4mL of cell-free culture supernatant.

  11. Development of cloud-operating platform for detention facility design

    Science.gov (United States)

    Tun Lee, Kwan; Hung, Meng-Chiu; Tseng, Wei-Fan; Chan, Yi-Ping

    2017-04-01

    In the past 20 years, the population of Taiwan has accumulated in urban areas. The land development has changed the hydrological environment and resulted in the increase of surface runoff and shortened the time to peak discharge. The change of runoff characteristics increases the flood risk and reduces resilient ability of the city during flood. Considering that engineering measures may not be easy to implement in populated cities, detention facilities set on building basements have been proposed to compromise the increase of surface runoff resulting from development activities. In this study, a web-based operational platform has been developed to integrate the GIS technologies, hydrological analyses, as well as relevant regulations for the design of detention facilities. The design procedure embedded in the system includes a prior selection of type and size of the detention facility, integrated hydrological analysis for the developing site, and inspection of relevant regulations. After login the platform, designers can access the system database to retrieve road maps, land use coverages, and storm sewer information. Once the type, size, inlet, and outlet of the detention facility are assigned, the system can acquire the rainfall intensity-duration-frequency information from adjacent rain gauges to perform hydrological analyses for the developing site. The increase of the runoff volume due to the development and the reduction of the outflow peak through the construction of the detention facility can be estimated. The outflow peak at the target site is then checked with relevant regulations to confirm the suitability of the detention facility design. The proposed web-based platform can provide a concise layout of the detention facility and the drainageway of the developing site on a graphical interface. The design information can also be delivered directly through a web link to authorities for inspecting to simplify the complex administrative procedures.

  12. Volume Regulated Channels

    DEFF Research Database (Denmark)

    Klausen, Thomas Kjær

    - serves a multitude of functions in the mammalian cell, regulating the membrane potential (Em), cell volume, protein activity and the driving force for facilitated transporters giving Cl- and Cl- channels a major potential of regulating cellular function. These functions include control of the cell cycle...... of volume perturbations evolution have developed system of channels and transporters to tightly control volume homeostasis. In the past decades evidence has been mounting, that the importance of these volume regulated channels and transporters are not restricted to the defense of cellular volume......, controlled cell death and cellular migration. Volume regulatory mechanisms has long been in focus for regulating cellular proliferation and my thesis work have been focusing on the role of Cl- channels in proliferation with specific emphasis on ICl, swell. Pharmacological blockage of the ubiquitously...

  13. An Optical Biosensing Platform using Reprecipitated Polyaniline Microparticles

    Science.gov (United States)

    Nemzer, Louis; Epstein, Arthur

    2009-03-01

    A great deal of effort remains focused on the goal of developing a continuous in vivo glucose monitoring system for patients with diabetes mellitus. We report a proof-of-concept study on a reagentless optical biosensing platform that circumvents the problems usually associated with direct glucose detection by utilizing the UV-VIS absorption properties of polyaniline, a biocompatible polymer. When the enzyme glucose oxidase is entrapped within reprecipitated polyaniline microparticles, a glucose molecule readily donates two protons and two electrons to the polyaniline, reversibly altering the polymer's oxidation state. The resultant change can be monitored by measuring the absorption at wavelengths that fall within the ``optical window'' for skin. The micro-structured morphology also insures a high surface-area to volume ratio. Data from in vitro prototype devices indicate that in the low enzyme-loading regime, the response can be fit to the Michaelis-Menten model for enzyme kinetics, but at higher enzyme loading, diffusion effects dominate. As a biosensing platform, the system also has the potential to be adapted to detect other biologically relevant analytes, including cholesterol and ethanol.

  14. Implementation of Wireless Communications Systems on FPGA-Based Platforms

    Directory of Open Access Journals (Sweden)

    Voros NS

    2007-01-01

    Full Text Available Wireless communications are a very popular application domain. The efficient implementation of their components (access points and mobile terminals/network interface cards in terms of hardware cost and design time is of great importance. This paper describes the design and implementation of the HIPERLAN/2 WLAN system on a platform including general purpose microprocessors and FPGAs. Detailed implementation results (performance, code size, and FPGA resources utilization are presented. The main goal of the design case presented is to provide insight into the design aspects of a complex system based on FPGAs. The results prove that an implementation based on microprocessors and FPGAs is adequate for the access point part of the system where the expected volumes are rather small. At the same time, such an implementation serves as a prototyping of an integrated implementation (System-on-Chip, which is necessary for the mobile terminals of a HIPERLAN/2 system. Finally, firmware upgrades were developed allowing the implementation of an outdoor wireless communication system on the same platform.

  15. Implementation of Wireless Communications Systems on FPGA-Based Platforms

    Directory of Open Access Journals (Sweden)

    N. S. Voros

    2007-02-01

    Full Text Available Wireless communications are a very popular application domain. The efficient implementation of their components (access points and mobile terminals/network interface cards in terms of hardware cost and design time is of great importance. This paper describes the design and implementation of the HIPERLAN/2 WLAN system on a platform including general purpose microprocessors and FPGAs. Detailed implementation results (performance, code size, and FPGA resources utilization are presented. The main goal of the design case presented is to provide insight into the design aspects of a complex system based on FPGAs. The results prove that an implementation based on microprocessors and FPGAs is adequate for the access point part of the system where the expected volumes are rather small. At the same time, such an implementation serves as a prototyping of an integrated implementation (System-on-Chip, which is necessary for the mobile terminals of a HIPERLAN/2 system. Finally, firmware upgrades were developed allowing the implementation of an outdoor wireless communication system on the same platform.

  16. Summary of Fe opacity measurement platform

    Energy Technology Data Exchange (ETDEWEB)

    Nagayama, Taisuke

    2016-05-01

    This powerpoint presentation goes over the Fe opacity measurement platform, including how the experiment works, what can be gathered from the measurements, what can be gathered from the simulations, and the limitations of the experiment.

  17. DESIGN OF OFFSHORE CONCRETE GRAVITY PLATFORMS

    African Journals Online (AJOL)

    loads from earth-quake for (earth-quake prone zones) are deployed to archive the design and ... Keywords: concrete gravity platform, offshore, foundation design, manufacturing, construction .... resistance to wind offered by such ice accumu-.

  18. 2011 Biomass Program Platform Peer Review: Feedstock

    Energy Technology Data Exchange (ETDEWEB)

    McCann, Laura [Office of Energy Efficiency and Renewable Energy (EERE), Washington, DC (United States)

    2012-02-01

    This document summarizes the recommendations and evaluations provided by an independent external panel of experts at the 2011 U.S. Department of Energy Biomass Program’s Feedstock Platform Review meeting.

  19. 2011 Biomass Program Platform Peer Review. Infrastructure

    Energy Technology Data Exchange (ETDEWEB)

    Lindauer, Alicia [Office of Energy Efficiency and Renewable Energy (EERE), Washington, DC (United States)

    2012-02-01

    This document summarizes the recommendations and evaluations provided by an independent external panel of experts at the 2011 U.S. Department of Energy Biomass Program’s Infrastructure Platform Review meeting.

  20. 2011 Biomass Program Platform Peer Review: Algae

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Joyce [Office of Energy Efficiency and Renewable Energy (EERE), Washington, DC (United States)

    2012-02-01

    This document summarizes the recommendations and evaluations provided by an independent external panel of experts at the 2011 U.S. Department of Energy Biomass Program’s Algae Platform Review meeting.

  1. Model refinement for offshore platforms: Experimental study

    Science.gov (United States)

    Zhang, Min; Chen, Zongli; Wu, Yanjian

    2017-08-01

    Offshore jacket platforms are widely used in offshore oil and gas exploitation. Finite element models of such structures need to have many degrees of freedom (DOFs) to represent the geometrical detail of complex structures, thereby leading to incompatibility in the number of DOFs of experimental models. To bring them both to the same order while ensuring that the essential eigen- properties of the refined model match those of experimental models, an extended model refinement procedure is presented in this paper. Vibration testing of an offshore jacket platform model is performed to validate the applicability of the proposed approach. A full-order finite element model of the platform is established and then tuned to meet the measured modal properties identified from the acceleration signals. Both model reduction and modal expansion methods are investigated, as well as various scenarios of sensor arrangements. Upon completion of the refinement, the updated jacket platform model matches the natural frequencies of the measured model well.

  2. Introducing Blackboard: an electronic learning platform.

    Science.gov (United States)

    Cader, Raffik; McGovern, Michael

    Blackboard, an internet-based platform for teaching and learning, was introduced to students on the preregistration nursing programme at Northumbria University. Although clear educational advantages were identified, there were also potential pitfalls.

  3. Designing platform independent mobile apps and services

    CERN Document Server

    Heckman, Rocky

    2016-01-01

    This book explains how to help create an innovative and future proof architecture for mobile apps by introducing practical approaches to increase the value and flexibility of their service layers and reduce their delivery time. Designing Platform Independent Mobile Apps and Services begins by describing the mobile computing landscape and previous attempts at cross platform development. Platform independent mobile technologies and development strategies are described in chapter two and three. Communication protocols, details of a recommended five layer architecture, service layers, and the data abstraction layer are also introduced in these chapters. Cross platform languages and multi-client development tools for the User Interface (UI) layer, as well as message processing patterns and message routing of the Service Int rface (SI) layer are explained in chapter four and five. Ways to design the service layer for mobile computing, using Command Query Responsibility Segregation (CQRS) and the Data Abstraction La...

  4. STUDY OF VARIOUS INTERNET OF THINGS PLATFORMS

    Directory of Open Access Journals (Sweden)

    Bhumi Nakhuva

    2015-12-01

    Full Text Available Internet of Things is a technological revolution which provides the vision of connected world of Things. Devices, people and systems are connected with one another in such a way that they can communicate with each other over Internet. So the form of communication from human-human is now turned into humanhuman, human-things and things- things. Variety of platforms are now a days available that can support entire development to deployment of IoT applications and systems. In this paper, we will first start with the introduction of IoT platforms as well as IoT middleware and then will discuss various IoT platforms, compare various IoT platforms and will end up with the conclusion.

  5. Embedded Based Miniaturized Universal Electrochemical Sensing Platform

    Directory of Open Access Journals (Sweden)

    Jiamin Chen

    2016-01-01

    Full Text Available We created an embedded sensing platform based on STM32 embedded system, with integrated carbon-electrode ionic sensor by using a self-made plug. Given ration of concentration-unknown nitrate liquid samples, this platform is able to measure the nitrate concentration in neutral environment. Response signals which were transmitted by the sensor can be displayed via a serial port to the computer screen or via Bluetooth to the smartphone. Processed by a fitting function, signals are transformed into related concentration. Through repeating the experiment many times, the accuracy and repeatability turned out to be excellent. The results can be automatically stored on smartphone via Bluetooth. We created this embedded sensing platform for field water quality measurement. This platform also can be applied for other micro sensors’ signal acquisition and data processing.

  6. Computing platforms for software-defined radio

    CERN Document Server

    Nurmi, Jari; Isoaho, Jouni; Garzia, Fabio

    2017-01-01

    This book addresses Software-Defined Radio (SDR) baseband processing from the computer architecture point of view, providing a detailed exploration of different computing platforms by classifying different approaches, highlighting the common features related to SDR requirements and by showing pros and cons of the proposed solutions. Coverage includes architectures exploiting parallelism by extending single-processor environment (such as VLIW, SIMD, TTA approaches), multi-core platforms distributing the computation to either a homogeneous array or a set of specialized heterogeneous processors, and architectures exploiting fine-grained, coarse-grained, or hybrid reconfigurability. Describes a computer engineering approach to SDR baseband processing hardware; Discusses implementation of numerous compute-intensive signal processing algorithms on single and multicore platforms; Enables deep understanding of optimization techniques related to power and energy consumption of multicore platforms using several basic a...

  7. 2011 Biomass Program Platform Peer Review. Sustainability

    Energy Technology Data Exchange (ETDEWEB)

    Eng, Alison Goss [Office of Energy Efficiency and Renewable Energy (EERE), Washington, DC (United States)

    2012-02-01

    This document summarizes the recommendations and evaluations provided by an independent external panel of experts at the 2011 U.S. Department of Energy Biomass Program’s Sustainability Platform Review meeting.

  8. 2011 Biomass Program Platform Peer Review: Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Haq, Zia [Office of Energy Efficiency and Renewable Energy (EERE), Washington, DC (United States)

    2012-02-01

    This document summarizes the recommendations and evaluations provided by an independent external panel of experts at the 2011 U.S. Department of Energy Biomass Program’s Analysis Platform Review meeting.

  9. Developing a social media platform for nurses.

    Science.gov (United States)

    Jackson, Jennifer; Kennedy, Maggie

    2015-11-18

    Social media tools provide opportunities for nurses to connect with colleagues and patients and to advance personally and professionally. This article describes the process of developing an innovative social media platform at a large, multi-centre teaching hospital, The Ottawa Hospital, Canada, and its benefits for nurses. The platform, TOH Nurses, was developed using a nursing process approach, involving assessment, planning, implementation and evaluation. The aim of this initiative was to address the barriers to communication inherent in the large number of nurses employed by the organisation, the physical size of the multi-centre hospital and the shift-work nature of nursing. The platform was used to provide educational materials for clinical nurses, and to share information about professional practice. The implications of using a social media platform in a healthcare setting were considered carefully during its development and implementation, including concerns regarding privacy and confidentiality.

  10. Energy-aware scheduling on multiprocessor platforms

    CERN Document Server

    Li, Dawei

    2014-01-01

    Multiprocessor platforms play important roles in modern computing systems, and appear in various applications, ranging from energy-limited hand-held devices to large data centers. As the performance requirements increase, energy-consumption in these systems also increases signi cantly. Dynamic Voltage and Frequency Scaling (DVFS), which allows processors to dynamically adjust the supply voltage and the clock frequency to operate on di erent power/energy levels, is considered an e ective way to achieve the goal of energy-saving. This book surveys existing works that have been on energy-aware task scheduling on DVFS multiprocessor platforms. Energy-aware scheduling problems are intrinsically optimization problems, the formulations of which greatly depend on the platform and task models under consideration. Thus, Energy-aware Scheduling on Multiprocessor Platforms covers current research on this topic and classi es existing works according to two key standards, namely, homogeneity/heterogeneity of multi processo...

  11. Cloud Based Applications and Platforms (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Brodt-Giles, D.

    2014-05-15

    Presentation to the Cloud Computing East 2014 Conference, where we are highlighting our cloud computing strategy, describing the platforms on the cloud (including Smartgrid.gov), and defining our process for implementing cloud based applications.

  12. ATF2 Proposal Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    Grishanov, B.I.; Logachev, P.; Podgorny, F.; Telnov, V.; /Novosibirsk, IYF; Angal-Kalinin, D.; Jones, J.; Kalinin, A.; /Daresbury; Napoly, O.; Payet, J.; /DAPNIA, Saclay; Braun, H.H.; Schulte, D.; Zimmermann, F.; /CERN; Appleby, R.; Barlow, R.; Bailey, I.; Jenner, L.; Jones, R.; Kourevlev, G.; /Cockcroft Inst.; Elsen, E.; Vogel, V.; Walker, N.; /DESY

    2006-02-27

    For achieving the high luminosity required at the International Linear Collider (ILC), it is critical to focus the beams to nanometer size with the ILC Beam Delivery System (BDS), and to maintain the beam collision with a nanometer-scale stability. To establish the technologies associated with this ultra-high precision beam handling, it has been proposed to implement an ILC-like final focus optics in an extension of the existing extraction beamline of ATF at KEK. The ATF is considered to be the best platform for this exercise, since it provides an adequate ultra-low emittance electron beam in a manner dedicated to the development of ILC. The two major goals for this facility, called ATF2, are: (A) Achievement of a 37 nm beam size, and (B) control of beam position down to 2 nm level. The scientific justification for the ATF2 project and its technical design have been described in Volume 1 of the ATF2 Proposal [1]. We present here Volume 2 of the ATF2 Proposal, in which we present specifics of the construction plans and the group organization to execute the research programs at ATF2. The sections in this report have been authored by relevant ATF2 subgroups within the International ATF Collaboration. The time line of the project is described in Section 2. Section 3 discuss the structure of the international collaboration. Sections 4 and 5 discuss budget considerations, which are presented as well as the design and construction tasks to be shared by the international collaboration at ATF2. Concluding remarks have been contributed by Dr. Ewan Paterson, Chair of the International Collaboration Board of the ATF collaboration.

  13. Offshore Minerals Management Platforms for the Gulf of Mexico (GOM), Geographic NAD83, MMS (2006) [platforms_mms_2006

    Data.gov (United States)

    Louisiana Geographic Information Center — Offshore Minerals Management Platforms for the Gulf of Mexico (GOM). Identifies the location of platforms in GOM. All platforms existing in the database are included.

  14. Creating Math Videos: Comparing Platforms and Software

    Science.gov (United States)

    Abbasian, Reza O.; Sieben, John T.

    2016-01-01

    In this paper we present a short tutorial on creating mini-videos using two platforms--PCs and tablets such as iPads--and software packages that work with these devices. Specifically, we describe the step-by-step process of creating and editing videos using a Wacom Intuos pen-tablet plus Camtasia software on a PC platform and using the software…

  15. Distributed E-Service Platform Model

    Institute of Scientific and Technical Information of China (English)

    PING Hu; YANG Hua; CHEN Jia-xun

    2002-01-01

    E-communication is an internet-oriented application platform for distributed system. The architecture of the platform is discussed in detail in this article. By theory and case study, the distributed model is proved flexible and practicable. Using services and core, developers can extend the e-community and leverage their applications.This model will be great helpful to build a new kind distributed, java-based, internet application.

  16. Virtual health platform for medical tourism purposes.

    Science.gov (United States)

    Martinez, Debora; Ferriol, Pedro; Tous, Xisco; Cabrer, Miguel; Prats, Mercedes

    2008-01-01

    This paper introduces an overview of the Virtual Health Platform (VHP), an alternative approach to create a functional PHR system in a medical tourism environment. The proposed platform has been designed in order to be integrated with EHR infrastructures and in this way it expects to be useful and more advantageous to the patient or tourist. Use cases of the VHP and its potential benefits summarize the analysis.

  17. Creating Math Videos: Comparing Platforms and Software

    Science.gov (United States)

    Abbasian, Reza O.; Sieben, John T.

    2016-01-01

    In this paper we present a short tutorial on creating mini-videos using two platforms--PCs and tablets such as iPads--and software packages that work with these devices. Specifically, we describe the step-by-step process of creating and editing videos using a Wacom Intuos pen-tablet plus Camtasia software on a PC platform and using the software…

  18. Handheld Microneedle-Based Electrolyte Sensing Platform.

    Energy Technology Data Exchange (ETDEWEB)

    Miller, Philip R. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Rivas, Rhiana [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Johnson, David [Aquila Technologies Group, Inc., Albuquerque, NM (United States); Edwards, Thayne L. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Koskelo, Markku [Aquila Technologies Group, Inc., Albuquerque, NM (United States); Shawa, Luay [Aquila Technologies Group, Inc., Albuquerque, NM (United States); Brener, Igal [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Chavez, Victor H. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Polsky, Ronen [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States)

    2015-11-01

    Sandia National Laboratories will provide technical assistance, within time and budget, to Requester on testing and analyzing a microneedle-based electrolyte sensing platform. Hollow microneedles will be fabricated at Sandia and integrated with a fluidic chip using plastic laminate prototyping technology available at Sandia. In connection with commercial ion selective electrodes the sensing platform will be tested for detection of electrolytes (sodium and/or potassium) within physiological relevant concent ration ranges.

  19. Flexible optical chemical sensor platform for BTX

    OpenAIRE

    Arias Espinoza, Juan Diego; Sazhnikov, Viacheslav; Sabik, Sami; Ionov, Dmitriy; Smits, Edsger; Kalathimekkad, Sandeep; Van Steenberge, Geert; Alfimov, Michail; Posniak, Malgorzata; Schoo, Herman

    2012-01-01

    An in-plane flexible sensor platform for BTX detection was developed using low-cost patterning techniques and foil-based optical components. The platform was produced by a combination of laser patterning, inkjet printing and capillary filling. Key optical components such as lightguides, opticalcladding layers and metallic interconnections were realized on low cost substrates such as paper and PET. The sensing mechanism is based on the change in fluorescence spectra of a reporter dye, supporte...

  20. SCEC Broadband Platform Strong Ground Motion Simulations

    Science.gov (United States)

    Kumar, S.; Callaghan, S.; Maechling, P. J.; Olsen, K. B.; Archuleta, R. J.; Somerville, P. G.; Graves, R. W.; Jordan, T. H.; Broadband Platform Working Group

    2011-12-01

    The Southern California Earthquake Center (SCEC) Broadband Platform is a collaborative software development project involving SCEC researchers, graduate students, and the SCEC Community Modeling Environment. The goal of the SCEC Broadband Simulation Platform is to generate broadband (0-10 Hz) ground motions for earthquakes using deterministic low-frequency and stochastic high-frequency simulations. SCEC developers have integrated complex scientific modules for rupture generation, low-frequency deterministic seismogram synthesis, high-frequency stochastic seismogram synthesis, and non-linear site effects calculation into a system that supports easy on-demand computation of broadband seismograms. The SCEC Broadband platform has two primary modes of operation, validation mode, and scenario mode. In validation mode, the earthquake modeling software calculates broadband seismograms for one of three earthquakes, Northridge, Loma Prieta, or Landers at sites with observed strong motion data. Then, the platform calculates goodness of fit measurements that quantify how well the model-based broadband seismograms match the observed seismograms for each event. In scenario mode, the user can specify a scenario earthquake and a list of sites and calculate ground motions at each site for the scenario event. In February 2011, SCEC released Broadband Platform 11.2 as an open-source scientific software distribution. Since that time, we have continued development of the platform by adding a new site response module and new goodness of fit measures by Mayhew and Olsen. Along with a source code distribution of the Broadband Platform, we now offer a virtual software image distribution of the platform to support its use on a variety of computing hardware and operating systems.

  1. Interfacing Clojure with Pogamut 3 platform

    Science.gov (United States)

    Gołuński, Marcel; WÄ siewicz, Piotr

    In this paper we present an interface between Pogamut 3 platform and Clojure programming language. Clojure is a state of the art functional language with roots in Lisp. Pogamut 3 is a framework that simplifies creation of embodied agents. Our goal was to introduce Clojure code in our agents logic. Simple emergent behavior of a group of agents was implemented using Clojure code. Performance of execution of Clojure code called from Pogamut platform was measured.

  2. Precision volume measurement system.

    Energy Technology Data Exchange (ETDEWEB)

    Fischer, Erin E.; Shugard, Andrew D.

    2004-11-01

    A new precision volume measurement system based on a Kansas City Plant (KCP) design was built to support the volume measurement needs of the Gas Transfer Systems (GTS) department at Sandia National Labs (SNL) in California. An engineering study was undertaken to verify or refute KCP's claims of 0.5% accuracy. The study assesses the accuracy and precision of the system. The system uses the ideal gas law and precise pressure measurements (of low-pressure helium) in a temperature and computer controlled environment to ratio a known volume to an unknown volume.

  3. INTERNAL CORROSION MONITORING IN OFFSHORE PLATFORMS

    Directory of Open Access Journals (Sweden)

    Fernando Benedicto Mainier

    2008-08-01

    Full Text Available Corrosion is one of the main causes of failures in equipment and pipes in off-shore oil production. These failures harm the process, slow the production operational chronogram, and generate high costs of maintenance, beyond generation risks to health and environment. Due to the fact that most of the equipment, tubing and pipes of production platforms are made of steel, in general, carbon steel, the industry of petroleum exploration will always coexist with the corrosive process. The use of a Corrosion Monitoring Plan to diagnostic, to control and to manage the evolution of corrosives process in off-shore oil platforms is the strategy proposed in this work to prevent problems as described above. The Internal Corrosion Monitoring Plan (ICMP, is based on lab analysis of the corrosively of fluids and residues showed periodically in off-shore operational platform; in the corrosion rate determined by the periodic use of test bodies installed inside off-shore oil platforms tubing systems, as mass loss coupons and electric resistance probes; and finally, in periodic operational data collect obtained during the off-shore oil platform systems operation. The ICMP will direct and manage the actions to be taken in case of aggravation of a corrosive process, quickly identifying to the corrosive mechanisms and its localization in the various systems of the platforms. The optimized use of the corrosion inhibitor and other chemical products are one of the main advantages of the ICMP.

  4. Study on Collision Characters for SPAR Platform

    Institute of Scientific and Technical Information of China (English)

    HU Zhi-qiang; CUI Wei-cheng

    2008-01-01

    This paper presents the research on the external mechanism of collision characters for a SPAR platform. The collision characters of SPAR platform have not attracted so much attention as that of ships in the past, because short of this kind of collision accidents reported. But with the increasing number of SPAR platforms in the world, the possibility of such kind of accident also increases. Therefore, it is necessary to master the character of SPAR collision. Model test technique is employed to study the external mechanism. The collision scenario is a ship colliding with a SPAR platform moored in the site with 1500 meters water depth. The striking ship hits the SPAR platform on the hard tank near water surface in its longitudinal direction. The specifics of the SPAR's motions and the tension forces of the mooring lines are collected to summarize the hydrodynamic characters in the collision scenario. It is found that the maximal displacements and the maximal pitch angles of the SPAR platform, and the maximal tension forces of mooring lines are all linearly proportional to the initial velocity of the striking ship basically. Mooring lines play elastic roles in the collision course.

  5. Centrifugal microfluidic platform for radiochemistry: potentialities for the chemical analysis of nuclear spent fuels.

    Science.gov (United States)

    Bruchet, Anthony; Taniga, Vélan; Descroix, Stéphanie; Malaquin, Laurent; Goutelard, Florence; Mariet, Clarisse

    2013-11-15

    The use of a centrifugal microfluidic platform is for the first time reported as an alternative to classical chromatographic procedures for radiochemistry. The original design of the microfluidic platform has been thought to fasten and simplify the prototyping process with the use of a circular platform integrating four rectangular microchips made of thermoplastic. The microchips, dedicated to anion-exchange chromatographic separations, integrate a localized monolithic stationary phase as well as injection and collection reservoirs. The results presented here were obtained with a simplified simulated nuclear spent fuel sample composed of non-radioactive isotopes of Europium and Uranium, in proportion usually found for uranium oxide nuclear spent fuel. While keeping the analytical results consistent with the conventional procedure (extraction yield for Europium of ≈97%), the use of the centrifugal microfluidic platform allowed to reduce the volume of liquid needed by a factor of ≈250. Thanks to their unique "easy-to-use" features, centrifugal microfluidic platforms are potential successful candidates for the downscaling of chromatographic separation of radioactive samples (automation, multiplexing, easy integration in glove-boxes environment and low cost of maintenance).

  6. Low Cost Hydrogen Production Platform

    Energy Technology Data Exchange (ETDEWEB)

    Timothy M. Aaron, Jerome T. Jankowiak

    2009-10-16

    conducted to identify any potential design deficiency related to the concept. The analysis showed that no fundamental design flaw existed with the concept, but additional simulations and prototypes would be required to verify the design prior to fabricating a production unit. These identified risks were addressed in detail during Phase II of the development program. Along with the models of the high temperature components, a detailed process and 3D design model of the remainder of system, including PSA, compression, controls, water treatment and instrumentation was developed and evaluated. Also, in Phase II of the program, laboratory/fullscale testing of the high temperature components was completed and stable operation/control of the system was verified. The overall design specifications and test results were then used to develop accurate hydrogen costs for the optimized system. Praxair continued development and testing of the system beyond the Phase II funding provided by the DOE through the end of 2008. This additional testing is not documented in this report, but did provide significant additional data for development of a prototype system as detailed in the Phase III proposal. The estimated hydrogen product costs were developed (2007 basis) for the 4.8 kg/h system at production rates of 1, 5, 10, 100 and 1,000 units built per year. With the low cost SMR approach, the product hydrogen costs for the 4.8 kg/h units at 50 units produced per year were approximately $3.02 per kg. With increasing the volume production to 1,000 units per year, the hydrogen costs are reduced by about 12% to $2.67 per kg. The cost reduction of only 12% is a result of significant design and fabrication efficiencies being realized in all levels of production runs through utilizing the DFMA principles. A simplified and easily manufactured design does not require large production volumes to show significant cost benefits. These costs represent a significant improvement and a new benchmark in the

  7. Low Cost Hydrogen Production Platform

    Energy Technology Data Exchange (ETDEWEB)

    Timothy M. Aaron, Jerome T. Jankowiak

    2009-10-16

    conducted to identify any potential design deficiency related to the concept. The analysis showed that no fundamental design flaw existed with the concept, but additional simulations and prototypes would be required to verify the design prior to fabricating a production unit. These identified risks were addressed in detail during Phase II of the development program. Along with the models of the high temperature components, a detailed process and 3D design model of the remainder of system, including PSA, compression, controls, water treatment and instrumentation was developed and evaluated. Also, in Phase II of the program, laboratory/fullscale testing of the high temperature components was completed and stable operation/control of the system was verified. The overall design specifications and test results were then used to develop accurate hydrogen costs for the optimized system. Praxair continued development and testing of the system beyond the Phase II funding provided by the DOE through the end of 2008. This additional testing is not documented in this report, but did provide significant additional data for development of a prototype system as detailed in the Phase III proposal. The estimated hydrogen product costs were developed (2007 basis) for the 4.8 kg/h system at production rates of 1, 5, 10, 100 and 1,000 units built per year. With the low cost SMR approach, the product hydrogen costs for the 4.8 kg/h units at 50 units produced per year were approximately $3.02 per kg. With increasing the volume production to 1,000 units per year, the hydrogen costs are reduced by about 12% to $2.67 per kg. The cost reduction of only 12% is a result of significant design and fabrication efficiencies being realized in all levels of production runs through utilizing the DFMA principles. A simplified and easily manufactured design does not require large production volumes to show significant cost benefits. These costs represent a significant improvement and a new benchmark in the

  8. Variable volume combustor

    Energy Technology Data Exchange (ETDEWEB)

    Ostebee, Heath Michael; Ziminsky, Willy Steve; Johnson, Thomas Edward; Keener, Christopher Paul

    2017-01-17

    The present application provides a variable volume combustor for use with a gas turbine engine. The variable volume combustor may include a liner, a number of micro-mixer fuel nozzles positioned within the liner, and a linear actuator so as to maneuver the micro-mixer fuel nozzles axially along the liner.

  9. Volume Regulated Channels

    DEFF Research Database (Denmark)

    Klausen, Thomas Kjær

    of volume perturbations evolution have developed system of channels and transporters to tightly control volume homeostasis. In the past decades evidence has been mounting, that the importance of these volume regulated channels and transporters are not restricted to the defense of cellular volume...... but are also essential for a number of physiological processes such as proliferation, controlled cell death, migration and endocrinology. The thesis have been focusing on two Channels, namely the swelling activated Cl- channel (ICl, swell) and the transient receptor potential Vanilloid (TRPV4) channel. I: Cl......- serves a multitude of functions in the mammalian cell, regulating the membrane potential (Em), cell volume, protein activity and the driving force for facilitated transporters giving Cl- and Cl- channels a major potential of regulating cellular function. These functions include control of the cell cycle...

  10. GEO Supersites Data Exploitation Platform

    Science.gov (United States)

    Lengert, W.; Popp, H.-J.; Gleyzes, J.-P.

    2012-04-01

    In the framework of the GEO Geohazard Supersite initiative, an international partnership of organizations and scientists involved in the monitoring and assessment of geohazards has been established. The mission is to advance the scientific understanding of geohazards by improving geohazard monitoring through the combination of in-situ and space-based data, and by facilitating the access to data relevant for geohazard research. The stakeholders are: (1) governmental organizations or research institutions responsible for the ground-based monitoring of earthquake and volcanic areas, (2) space agencies and satellite operators providing satellite data, (3) the global geohazard scientific community. The 10.000's of ESA's SAR products are accessible, since beginning 2008, using ESA's "Virtual Archive", a Cloud Computing assets, allowing the global community an utmost downloading performance of these high volume data sets for mass-market costs. In the GEO collaborative context, the management of ESA's "Virtual Archive" and the ordering of these large data sets is being performed by UNAVCO, who is also coordinating the data demand for the several hundreds of co-PIs. ESA is envisaging to provide scientists and developers access to a highly elastic operational e-infrastructure, providing interdisciplinary data on a large scale as well as tools ensuring innovation and a permanent evolution of the products. Consequently, this science environment will help in defining and testing new applications and technologies fostering innovation and new science findings. In Europe, the collaboration between EPOS, "European Plate Observatory System" lead by INGV, and ESA with support of DLR, ASI, and CNES are the main institutional stakeholders for the GEO Supersites contributing also to a unifying e-infrastructure. The overarching objective of the Geohazard Supersites is: "To implement a sustainable Global Earthquake Observation System and a Global Volcano Observation System as part of the

  11. On Curating Multimodal Sensory Data for Health and Wellness Platforms

    Science.gov (United States)

    Amin, Muhammad Bilal; Banos, Oresti; Khan, Wajahat Ali; Muhammad Bilal, Hafiz Syed; Gong, Jinhyuk; Bui, Dinh-Mao; Cho, Soung Ho; Hussain, Shujaat; Ali, Taqdir; Akhtar, Usman; Chung, Tae Choong; Lee, Sungyoung

    2016-01-01

    In recent years, the focus of healthcare and wellness technologies has shown a significant shift towards personal vital signs devices. The technology has evolved from smartphone-based wellness applications to fitness bands and smartwatches. The novelty of these devices is the accumulation of activity data as their users go about their daily life routine. However, these implementations are device specific and lack the ability to incorporate multimodal data sources. Data accumulated in their usage does not offer rich contextual information that is adequate for providing a holistic view of a user’s lifelog. As a result, making decisions and generating recommendations based on this data are single dimensional. In this paper, we present our Data Curation Framework (DCF) which is device independent and accumulates a user’s sensory data from multimodal data sources in real time. DCF curates the context of this accumulated data over the user’s lifelog. DCF provides rule-based anomaly detection over this context-rich lifelog in real time. To provide computation and persistence over the large volume of sensory data, DCF utilizes the distributed and ubiquitous environment of the cloud platform. DCF has been evaluated for its performance, correctness, ability to detect complex anomalies, and management support for a large volume of sensory data. PMID:27355955

  12. On Curating Multimodal Sensory Data for Health and Wellness Platforms

    Directory of Open Access Journals (Sweden)

    Muhammad Bilal Amin

    2016-06-01

    Full Text Available In recent years, the focus of healthcare and wellness technologies has shown a significant shift towards personal vital signs devices. The technology has evolved from smartphone-based wellness applications to fitness bands and smartwatches. The novelty of these devices is the accumulation of activity data as their users go about their daily life routine. However, these implementations are device specific and lack the ability to incorporate multimodal data sources. Data accumulated in their usage does not offer rich contextual information that is adequate for providing a holistic view of a user’s lifelog. As a result, making decisions and generating recommendations based on this data are single dimensional. In this paper, we present our Data Curation Framework (DCF which is device independent and accumulates a user’s sensory data from multimodal data sources in real time. DCF curates the context of this accumulated data over the user’s lifelog. DCF provides rule-based anomaly detection over this context-rich lifelog in real time. To provide computation and persistence over the large volume of sensory data, DCF utilizes the distributed and ubiquitous environment of the cloud platform. DCF has been evaluated for its performance, correctness, ability to detect complex anomalies, and management support for a large volume of sensory data.

  13. Integrated microfluidic platforms for investigating neuronal networks

    Science.gov (United States)

    Kim, Hyung Joon

    This dissertation describes the development and application of integrated microfluidics-based assay platforms to study neuronal activities in the nervous system in-vitro. The assay platforms were fabricated using soft lithography and micro/nano fabrication including microfluidics, surface patterning, and nanomaterial synthesis. The use of integrated microfluidics-based assay platform allows culturing and manipulating many types of neuronal tissues in precisely controlled microenvironment. Furthermore, they provide organized multi-cellular in-vitro model, long-term monitoring with live cell imaging, and compatibility with molecular biology techniques and electrophysiology experiment. In this dissertation, the integrated microfluidics-based assay platforms are developed for investigation of neuronal activities such as local protein synthesis, impairment of axonal transport by chemical/physical variants, growth cone path finding under chemical/physical cues, and synaptic transmission in neuronal circuit. Chapter 1 describes the motivation, objectives, and scope for developing in-vitro platform to study various neuronal activities. Chapter 2 introduces microfluidic culture platform for biochemical assay with large-scale neuronal tissues that are utilized as model system in neuroscience research. Chapter 3 focuses on the investigation of impaired axonal transport by beta-Amyloid and oxidative stress. The platform allows to control neuronal processes and to quantify mitochondrial movement in various regions of axons away from applied drugs. Chapter 4 demonstrates the development of microfluidics-based growth cone turning assay to elucidate the mechanism underlying axon guidance under soluble factors and shear flow. Using this platform, the behaviors of growth cone of mammalian neurons are verified under the gradient of inhibitory molecules and also shear flow in well-controlled manner. In Chapter 5, I combine in-vitro multicellular model with microfabricated MEA

  14. Embedded Linux platform for data acquisition systems

    Energy Technology Data Exchange (ETDEWEB)

    Patel, Jigneshkumar J., E-mail: jjp@ipr.res.in [Institute for Plasma Research, Gandhinagar, Gujarat (India); Reddy, Nagaraj, E-mail: nagaraj.reddy@coreel.com [Sandeepani School of Embedded System Design, Bangalore, Karnataka (India); Kumari, Praveena, E-mail: praveena@ipr.res.in [Institute for Plasma Research, Gandhinagar, Gujarat (India); Rajpal, Rachana, E-mail: rachana@ipr.res.in [Institute for Plasma Research, Gandhinagar, Gujarat (India); Pujara, Harshad, E-mail: pujara@ipr.res.in [Institute for Plasma Research, Gandhinagar, Gujarat (India); Jha, R., E-mail: rjha@ipr.res.in [Institute for Plasma Research, Gandhinagar, Gujarat (India); Kalappurakkal, Praveen, E-mail: praveen.k@coreel.com [Sandeepani School of Embedded System Design, Bangalore, Karnataka (India)

    2014-05-15

    Highlights: • The design and the development of data acquisition system on FPGA based reconfigurable hardware platform. • Embedded Linux configuration and compilation for FPGA based systems. • Hardware logic IP core and its Linux device driver development for the external peripheral to interface it with the FPGA based system. - Abstract: This scalable hardware–software system is designed and developed to explore the emerging open standards for data acquisition requirement of Tokamak experiments. To address the future need for a scalable data acquisition and control system for fusion experiments, we have explored the capability of software platform using Open Source Embedded Linux Operating System on a programmable hardware platform such as FPGA. The idea was to identify the platform which can be customizable, flexible and scalable to support the data acquisition system requirements. To do this, we have selected FPGA based reconfigurable and scalable hardware platform to design the system with Embedded Linux based operating system for flexibility in software development and Gigabit Ethernet interface for high speed data transactions. The proposed hardware–software platform using FPGA and Embedded Linux OS offers a single chip solution with processor, peripherals such ADC interface controller, Gigabit Ethernet controller, memory controller amongst other peripherals. The Embedded Linux platform for data acquisition is implemented and tested on a Virtex-5 FXT FPGA ML507 which has PowerPC 440 (PPC440) [2] hard block on FPGA. For this work, we have used the Linux Kernel version 2.6.34 with BSP support for the ML507 platform. It is downloaded from the Xilinx [1] GIT server. Cross-compiler tool chain is created using the Buildroot scripts. The Linux Kernel and Root File System are configured and compiled using the cross-tools to support the hardware platform. The Analog to Digital Converter (ADC) IO module is designed and interfaced with the ML507 through Xilinx

  15. Remote control of a mobile platform with a smartphone

    OpenAIRE

    Majcen, Gregor

    2011-01-01

    This thesis describes a system for remote control of a mobile platform using a smartphone. As a mobile platform is used an iRobot Roomba vacuum cleaner equipped with a wireless router and a camera. The mobile platform and the smartphone communicate over the internet. The smartphone is used as a gaming console to control the movement of the mobile platform.

  16. Demand Heterogeneity and the Adoption of Platform Complements

    NARCIS (Netherlands)

    J. Rietveld (Joost); J.P. Eggers

    2016-01-01

    textabstractThis paper offers a demand-based theory of how platform maturity affects the adoption of platform complements. We argue that differences between early and late adopters of the platform include willingness to pay for the platform-and-complement bundle, risk preferences, preference for

  17. Demand Heterogeneity and the Adoption of Platform Complements

    NARCIS (Netherlands)

    J. Rietveld (Joost); J.P. Eggers

    2016-01-01

    textabstractThis paper offers a demand-based theory of how platform maturity affects the adoption of platform complements. We argue that differences between early and late adopters of the platform include willingness to pay for the platform-and-complement bundle, risk preferences, preference for nov

  18. ROHDIP: Resource Oriented Heterogeneous Data Integration Platform

    Directory of Open Access Journals (Sweden)

    Wael Shehab

    2016-09-01

    Full Text Available During the last few years, the revolution of social networks such as Facebook, Twitter, and Instagram led to a daily increasing of data that are heterogeneous in their sources, data models, and platforms. Heterogeneous data sources have many forms such as the www, deep web, relational databases systems, No-SQL database systems, hierarchal data systems, semi-structured files, in which data are usually allocated on different machines (distributed and have different data models (heterogeneous. Large-scale data integration efforts demonstrate that their most valuable contribution is implementing a data integration platform that provides a uniform access to the heterogeneous data sources, as well as the different versions of data reported by the same data source over time. Furthermore, the platform must be able to integrate data from a broad range of data authoring devices and database management systems. It also should be accessible by almost types of data querying devices to ensure globally querying the integration platform from any place on earth anytime and receiving the query result in any data format. In this paper, we create a resource oriented heterogeneous data integration platform (ROHDIP that facilitates the data integration process and implements the objectives discussed above. We use the resource oriented architecture ROA to support the uniform access by most types of data querying devices from anywhere and to improve the query response time.

  19. Anticipating Alternative Futures for the Platform Economy

    Directory of Open Access Journals (Sweden)

    Mikko Dufva

    2017-09-01

    Full Text Available Despite the considerable hype around platforms, our understanding of what the platform economy means and what drivers will define future development trajectories is limited. Companies and policy makers have a great need to investigate what potential opportunities will arise from the platform economy. A shared perception of uncertainties and a strong vision are prerequisites for the development of the platform economy. In this article, we describe a systematic way to develop a resilient vision for a new platform ecosystem, both from the viewpoint of national policy makers and corporate strategy makers in the heavy engineering industry. The process uses morphological analysis for scenario development and robust portfolio modelling for creating resilient strategies. The results include a list of key uncertainties, three general scenarios (sustainable development by Europe; polarization driven by China and the United States; US-driven fast, unreliable growth as well as steel-industry specific scenarios based on these uncertainties, elements of a resilient vision, and strategies for coping with the uncertainties described by the scenarios.

  20. Vessel, motion platform, method for compensating motions of a vessel and use of a stewart platform

    NARCIS (Netherlands)

    Van der Tempel, J.; Salzmann, D.J.C.; Koch, J.; Gerner. F.; Goebel, A.J.

    2007-01-01

    A vessel (1) with a motion compensation platform (4), which platform is provided with at least one carrier (6) for bearing, moving and/or transferring a load, actuators (5) for moving the carrier relative to the vessel, preferably in six degrees of freedom, a control system for driving the actuators

  1. Volume regulation in epithelia

    DEFF Research Database (Denmark)

    Larsen, Erik Hviid; Hoffmann, Else Kay

    2016-01-01

    function of iso-osmotic fluid transport that depends on Na+ recirculation. The causative relationship is discussed for a fluid-absorbing and a fluid-secreting epithelium of which the Na+ recirculation mechanisms have been identified. A large number of transporters and ion channels involved in cell volume...... regulation are cloned. The volume-regulated anion channel (VRAC) exhibiting specific electrophysiological characteristics seems exclusive to serve cell volume regulation. This is contrary to K+ channels as well as cotransporters and exchange mechanisms that may serve both transepithelial transport and cell...

  2. Towards the Amplituhedron Volume

    CERN Document Server

    Ferro, Livia; Orta, Andrea; Parisi, Matteo

    2015-01-01

    It has been recently conjectured that scattering amplitudes in planar N=4 super Yang-Mills are given by the volume of the (dual) amplituhedron. In this paper we show some interesting connections between the tree-level amplituhedron and a special class of differential equations. In particular we demonstrate how the amplituhedron volume for NMHV amplitudes is determined by these differential equations. The new formulation allows for a straightforward geometric description, without any reference to triangulations. Finally we discuss possible implications for volumes related to generic N^kMHV amplitudes.

  3. Unsteady flow volumes

    Energy Technology Data Exchange (ETDEWEB)

    Becker, B.G.; Lane, D.A.; Max, N.L.

    1995-03-01

    Flow volumes are extended for use in unsteady (time-dependent) flows. The resulting unsteady flow volumes are the 3 dimensional analog of streamlines. There are few examples where methods other than particle tracing have been used to visualize time varying flows. Since particle paths can become convoluted in time there are additional considerations to be made when extending any visualization technique to unsteady flows. We will present some solutions to the problems which occur in subdivision, rendering, and system design. We will apply the unsteady flow volumes to a variety of field types including moving multi-zoned curvilinear grids.

  4. Bronchoscopic lung volume reduction

    Directory of Open Access Journals (Sweden)

    M. I. Polkey

    2006-12-01

    Full Text Available Surgical lung volume reduction can improve exercise performance and forced expiratory volume in one second in patients with emphysema. However, the procedure is associated with a 5% mortality rate and a nonresponse rate of 25%. Accordingly, interest has focused on alternative ways of reducing lung volume. Two principle approaches are used: collapse of the diseased area using blockers placed endobronchially and the creation of extrapulmonary pathways. Preliminary data from the former approach suggest that it can be successful and that the magnitude of success is related to reduction in dynamic hyperinflation.

  5. Communication System for CIMS Application Integration Platform

    Institute of Scientific and Technical Information of China (English)

    1999-01-01

    CIMS has seen the growth of multiple incompatible hardware architectur es, each architecture supporting several incompatible operating systems, and eac h platform operating with various incompatible development tools (e.g., programm ing language compilers, DBMS, etc.) and one or more incompatible graphic user in terfaces. Also, the growth of the Internet, the World-Wide Web, has introduced new dimensio ns of complexity into the development process. All of these must be dealt with a s the application is made workable in a distributed client-server environment. This paper outlines the architecture of a communication system for the CIMS appl ication integration platform. The communication system makes possible the reque st for service across heterogeneous platforms and networks, and provides some co mmon solutions to issues common to CIMS applications.

  6. GAVIP: A Platform for Gaia Data Analysis

    CERN Document Server

    Vagg, Daniel; hÓgáin, Fionn Ó; McBreen, Sheila; Hanlon, Lorraine; Lynn, David; O'Mullane, William

    2016-01-01

    Gaia is a major European Space Agency (ESA) astrophysics mission designed to map and analyse 10$^9$ stars, ultimately generating more than 1 PetaByte of data products. As Gaia data becomes publicly available and reaches a wider audience, there is an increasing need to facilitate the further use of Gaia products without needing to download large datasets. The Gaia Added Value Interface Platform (GAVIP) is designed to address this challenge by providing an innovative platform within which scientists can submit and deploy code, packaged as "Added Value Interfaces" (AVIs), which will be executed close to the data. Deployed AVIs and associated outputs may also be made available to other GAVIP platform users, thus providing a mechanism for scientific experiment reproducibility. This paper describes the capabilities and features of GAVIP.

  7. The FLP microsatellite platform flight operations manual

    CERN Document Server

    2016-01-01

    This book represents the Flight Operations Manual for a reusable microsatellite platform – the “Future Low-cost Platform” (FLP), developed at the University of Stuttgart, Germany. It provides a basic insight on the onboard software functions, the core data handling system and on the power, communications, attitude control and thermal subsystem of the platform. Onboard failure detection, isolation and recovery functions are treated in detail. The platform is suited for satellites in the 50-150 kg class and is baseline of the microsatellite “Flying Laptop” from the University. The book covers the essential information for ground operators to controls an FLP-based satellite applying international command and control standards (CCSDS and ECSS PUS). Furthermore it provides an overview on the Flight Control Center in Stuttgart and on the link to the German Space Agency DLR Ground Station which is used for early mission phases. Flight procedure and mission planning chapters complement the book. .

  8. Development of a Zigbee platform for bioinstrumentation.

    Science.gov (United States)

    Cifuentes, Carlos A; Gentiletti, Gabriel G; Suarez, Marco J; Rodriguez, Luis E

    2010-01-01

    This paper presents the development of a network platform which allows connecting multiple individual wireless devices for transmitting bioelectrics and biomechanics signals for application in a hospital network, or continuous monitoring in a patient's diary life. The Zigbee platform development proposal was made in three stages: 1) Hardware development, including the construction of a prototype network node and the integration of sensors, (2) Evaluation, in order to define the specifications of each node and scope of communication and (3) The Zigbee Network Implementation for bioinstrumentation based on ZigBee Health Care public application profile (ZHC). Finally, this work presents the experimental results based on measurements of Lost Packets and LQI (Link Quality Indicator), and the Zigbee Platform configuration for Bioinstrumentation in operation.

  9. Electronics Platform of PS Linac 1 Preinjector

    CERN Multimedia

    1974-01-01

    For servicing during shutdowns, a draw-bridge from a door in the Faraday cage led to the "electronics platform" of the linac 1 preinjector (at 520 kV when in operation) and the top of the electronics platform was lifted on hydraulic jacks for easy access. Henry Charmot is busy with a service. The platform contained the electronics for the ion source, controlled from outside the Faraday cage via an infrared optical link. The ion source, also at 520 kV potential, is housed in the drum, visible in the background, on the insulator column, which at its right end is mounted at ground potential. Behind the wall, to the right, is the 50 MeV linac 1. See also 7403064X, 7403066X, 7403124.

  10. An Experimental Study of an Offshore Platform

    DEFF Research Database (Denmark)

    Brincker, Rune; Asmussen, John Christian; Andersen, Palle

    This report describes the results of an analysis of the ambient response data collected from a Venezuelan near-shore offshore platform constructed in 1992. Recording of the data have been constantly done during the period from May 1993 to July 1994. Using these data the structural integrity...... of the multi-pile offshore platform is investigated by using a vibration based damage detection scheme. Changes in structural integrity are assumed to be reflected in the modal parameters estimated from only output data using an Auto-Regressive Moving Average (ARMA) model. Before the calibration of the ARMA...... model the quality of the measured data have been investigated. The estimated modal parameters and their corresponding variances are used as input to a probability based damage indicator. This indicator indicates, that since the construction of the platform, minor structural changes have taken place....

  11. Thermal performance testing of the Explorer Platform

    Science.gov (United States)

    Wasson, David; Ducas, William; Ousley, Wes

    1993-01-01

    The Explorer Platform (EP) has been designed to accommodate on-orbit payload and bus module changeout via Space Transportation System (STS) servicing. Such a versatile spacecraft platform designed to experience widely different environmental exposures and operational conditions, coupled with program constraints on schedule and budget, presented a challenge to implementing a technically sound thermal vacuum/thermal balance test program. This paper discusses thermal performance tests implemented at the subsystem and system levels, and the risks accepted resulting from test sequence, configuration. and tests omitted from the program. No thermal cycling or thermal balance tests were performed on the integrated spacecraft level, although both the Payload (EUVE) and Platform (EP) received independent testing. The decision to take this approach is discussed with respect to the thermal design and the associated risks taken to maintain budget and schedule.

  12. Synthetic biology platform technologies for antimicrobial applications.

    Science.gov (United States)

    Braff, Dana; Shis, David; Collins, James J

    2016-10-01

    The growing prevalence of antibiotic resistance calls for new approaches in the development of antimicrobial therapeutics. Likewise, improved diagnostic measures are essential in guiding the application of targeted therapies and preventing the evolution of therapeutic resistance. Discovery platforms are also needed to form new treatment strategies and identify novel antimicrobial agents. By applying engineering principles to molecular biology, synthetic biologists have developed platforms that improve upon, supplement, and will perhaps supplant traditional broad-spectrum antibiotics. Efforts in engineering bacteriophages and synthetic probiotics demonstrate targeted antimicrobial approaches that can be fine-tuned using synthetic biology-derived principles. Further, the development of paper-based, cell-free expression systems holds promise in promoting the clinical translation of molecular biology tools for diagnostic purposes. In this review, we highlight emerging synthetic biology platform technologies that are geared toward the generation of new antimicrobial therapies, diagnostics, and discovery channels. Copyright © 2016 Elsevier B.V. All rights reserved.

  13. Azimut: a multimodal locomotion robotic platform

    Science.gov (United States)

    Michaud, Francois; Letourneau, Dominic; Arsenault, Martin; Bergeron, Yann; Cadrin, Richard; Gagnon, Frederic; Legault, Marc-Antoine; Millette, Mathieu; Pare, Jean-Francois; Tremblay, Marie-Christine; Lepage, Pierre; Morin, Yan; Caron, Serge

    2003-09-01

    Other than from its sensing and processing capabilities, a mobile robotic platform can be limited in its use by its ability to move in the environment. A wheeled robot works well on flat surfaces. Tracks are useful over rough terrains, while legs allow a robot to move over obstacles. In this paper we present a new concept of mobile robot with the objective of combining different locomotion mechanisms on the same platform to increase its locomotion capabilities. After presenting a review of multi-modal robotic platforms, we describe the design of our robot called AZIMUT. AZIMUT combines wheels, legs and tracks to move in three-dimensional environments. The robot is symmetrical and is made of four independent leg-track-wheel articulations. It can move with its articulations up, down or straight, or move sideways without changing the robot's orientation. The robot could be used in surveillance and rescue missions, exploration or operation in hazardous environments.

  14. Media content management on the DTV platform

    Science.gov (United States)

    Yeo, Boon-Lock; Yeung, Minerva M.

    1998-12-01

    Digital TV offers many advantages over analog TV. The obvious advantages are higher picture resolution and superior quality, more programs for the same channel bandwidth, and potential for mixed video and data broadcasting. In addition, the reception of video, audio, and data in digital form, offer new opportunities for better filtering, management and organization of the content, during and after the broadcast. The platform on which these media content management operations are performed is similar to the computing platform, with which we are familiar. Hence, the goals are to process incoming bits of data and to generate output for users' reception and/or interactivity. In this paper, we present our vision and summarize our research activities in media content management on the DTV platform. In particular, we will focus on three key areas, namely, channel surfing, digital video recording, and content filtering. We will also demonstrate how media content management can offer new and better viewing experiences in the era of DTV.

  15. Design for game based learning platforms

    DEFF Research Database (Denmark)

    Sørensen, Birgitte Holm; Meyer, Bente

    2010-01-01

    This paper focuses on the challenges related to the design of game based learning platforms for formal learning contexts that are inspired by the pupil's leisure time related use of web 2.0. The paper is based on the project Serious Games on a Global Market Place (2007-2011) founded by the Danish...... Council for Strategic Research, in which an online game-based platform for English as a foreign language in primary school is studied. The paper presents a model for designing for game based learning platforms. This design is based on cultural and ethnographic based research on children's leisure time use...... of web 2.0 and integrates theories of learning, didactics, games, play, communication, multimodality and different pedagogical approaches. In relation to the introduced model the teacher role is discussed....

  16. What are the key sucess factors of MOOC platforms?

    OpenAIRE

    Bento, Lourenço de Moura Souto

    2014-01-01

    This thesis analyzes key characteristics of Massive Open Online Courses (MOOCs) platforms in order to assess what makes such platforms successful. Three challenges of MOOC platforms were determined from the review of the literature: dropout rates, sustainability and plagiarism. Primary data was gathered from a sample of MOOC platforms, both on the characteristics of the platforms themselves and their internet traffic data. We performed a statistical correlation analysis using Traffic Rank as ...

  17. CONFIGURATION DEVELOPMENT ON THE PLATFORM 1C FOR ENTERPRISE AUTOMATION

    OpenAIRE

    О.L. LIAKHOV; T.A. DMYTRENKO; A.О. TVERDOKHLIB; T.M. DERKACH; A.O. DMYTRENKO

    2015-01-01

    In this paper, the results of configuration development on the platform 1C for limited liability companies were presented. The object of study is the development process configuration platform 1C. The purpose of the study is the technological platform “1C: Enterprise”. The tasks included analyzing the technological platform “1C: Enterprise”, comparing the most popular ERP-systems, configurator devel-opment on the platform 1C. Such research methods as structured programming techniques and meth...

  18. The macrofouling on offshore platforms at Ravenna

    Energy Technology Data Exchange (ETDEWEB)

    Relini, G.; Tixi, F.; Relini, M.; Torchia, G. [Universita degli Studi di Genova-Istituto di Zoologia (Italy). Lab. di Biologia Marina e Ecologia Animale

    1998-12-31

    The fouling which settles on gas platform piles was studied using samples taken in 1993 from the PCWA and ANTARES platforms positioned, at 7 and 10.5 km from the shore respectively and on bottoms at 12 m and 14 m in the Adriatic Sea. For each platform a pile was chosen as representative of the macrofouling found on the whole platform. In March and September 1993 samples were obtained by scraping an area of 600 cm{sup 2} from three or four different aspects (North, East, South, West), at the same depth. Samples were taken at depths of 0.5, 5.5 and 12 m on PCWA and 0.5, 7 and 12 m on ANTARES. Photographs and video recordings taken over the whole length of the chosen pile were used for an additional description of the settlement. On both platforms the macrofouling was characterized by a dominance of mussels from sea surface to a depth of about 10m. Near the bottom of the bivalve Crassostrea gigas, barnacles, hydroids and serpulids were more important. The presence of the bryozoan Schizoporella errata (present only at ANTARES) and the zoanthid Epizoanthus arenaceus (present only at PCWA) were the main differences at this depth. The fouling, or mussel weights, of the two platforms were similar for the two seasons, even though the highest values were registered in September on PCWA (1m) with 1561.3 g/dm{sup 2}, of which 1553 g/dm{sup 2} comprised mussels. A comparison is drawn with a previous fouling experiment (which used one-year panels) carried out in 1975-76. (Author)

  19. PRIMA: A new, competitive small satellite platform

    Science.gov (United States)

    Galeazzi, Claudio

    2000-03-01

    ASI, the Italian Space Agency, is going to finance a developing of a small satellite platforms production line called PRIMA (Piattaforma Riconfigurabile Italiana Multi-Applicativa) with Alenia Aerospazio partnership as Prime Contractor and sub-contractors preferably chosen within the Italian Space Industries. The main objective of the program is to develop a multi-mission, easily adaptable Platform for LEO orbits, allowing rapid, efficient and low cost bus for applicative and scientific missions. The Italian national space plan foresees for the enf of 2001 the build up of the Skymed/Cosmo constellation as applicative Earth observation program plus a number of small scientific spacecraft with a rate of 2 missions each three years. To fulfil these schedules, the PRIMA platform should complete its development and qualification program in order to be ready for the first unit (protoqualification flight) to interface the first payload (Science or Applicative). The intrinsic modularity of PRIMA should allow it to adapt itself to a large variety of missions in LEO orbits with minor modifications. The design will be conducted in order to get an advanced Platform able to meet a large set of missions, payloads and launcher specifications. The platform will be completed by a ground control centre adapted to the monitoring of PRIMA based satellites. PRIMA thus offers a very attractive alternative to large-scale missions in terms of costs and completion time. The paper will describe the technical aspects of PRIMA Platform, with particular emphasis put onto its flexibility and reconfigurability for different missions. The System and S/S architectures will also be presented and defined in view of selected mission cases. The AIV/AIT aspects will be discussed, with a discussion of the applicability of Globalstar™ approaches, facility and heritage. Finally, a brief overview of PRIMA first applications /SkyMed/COSMO and David) will be given.

  20. Emerging heterogeneous integrated photonic platforms on silicon

    Directory of Open Access Journals (Sweden)

    Fathpour Sasan

    2015-05-01

    Full Text Available Silicon photonics has been established as a mature and promising technology for optoelectronic integrated circuits, mostly based on the silicon-on-insulator (SOI waveguide platform. However, not all optical functionalities can be satisfactorily achieved merely based on silicon, in general, and on the SOI platform, in particular. Long-known shortcomings of silicon-based integrated photonics are optical absorption (in the telecommunication wavelengths and feasibility of electrically-injected lasers (at least at room temperature. More recently, high two-photon and free-carrier absorptions required at high optical intensities for third-order optical nonlinear effects, inherent lack of second-order optical nonlinearity, low extinction ratio of modulators based on the free-carrier plasma effect, and the loss of the buried oxide layer of the SOI waveguides at mid-infrared wavelengths have been recognized as other shortcomings. Accordingly, several novel waveguide platforms have been developing to address these shortcomings of the SOI platform. Most of these emerging platforms are based on heterogeneous integration of other material systems on silicon substrates, and in some cases silicon is integrated on other substrates. Germanium and its binary alloys with silicon, III–V compound semiconductors, silicon nitride, tantalum pentoxide and other high-index dielectric or glass materials, as well as lithium niobate are some of the materials heterogeneously integrated on silicon substrates. The materials are typically integrated by a variety of epitaxial growth, bonding, ion implantation and slicing, etch back, spin-on-glass or other techniques. These wide range of efforts are reviewed here holistically to stress that there is no pure silicon or even group IV photonics per se. Rather, the future of the field of integrated photonics appears to be one of heterogenization, where a variety of different materials and waveguide platforms will be used for

  1. AutoCAD platform customization autolisp

    CERN Document Server

    Ambrosius, Lee

    2014-01-01

    Customize and personalize programs built on the AutoCAD platform AutoLISP is the key to unlocking the secrets of a more streamlined experience using industry leading software programs like AutoCAD, Civil 3D, Plant 3D, and more. AutoCAD Platform Customization: AutoLISP provides real-world examples that show you how to do everything from modifying graphical objects and reading and setting system variables to communicating with external programs. It also features a resources appendix and downloadable datasets and customization examples-tools that ensure swift and easy adoption. Find out how to r

  2. Implementing Product Platforms: A Case Study

    DEFF Research Database (Denmark)

    Nielsen, Ole Fiil; Mortensen, Niels Henrik

    2006-01-01

    The paper describes a case study dealing with the process of creating and implementing a product platform. The paper espessially deals with the fact that to obtain the benefits of platforms a permanent change in behaviour in product development must be ensured. This change in behaviour requires...... acceptance and approval from the organisation in general and the commitment from management to enforce agreed-upon decisions. The case study itself was performed in the Danish company LEGO Group. The case study had two objectives: To create a technical architecture and align this architecture...

  3. Coupling methodology within the software platform alliances

    Energy Technology Data Exchange (ETDEWEB)

    Montarnal, Ph.; Deville, E.; Adam, E.; Bengaouer, A. [CEA Saclay, Dept. de Modelisation des Systemes et Structures 91 - Gif-sur-Yvette (France); Dimier, A.; Gaombalet, J.; Loth, L. [Agence Nationale pour la Gestion des Dechets Radioactifs (ANDRA), 92 - Chatenay Malabry (France); Chavant, C. [Electricite de France (EDF), 92 - Clamart (France)

    2005-07-01

    CEA, ANDRA and EDF are jointly developing the software platform ALLIANCES which aim is to produce a tool for the simulation of nuclear waste storage and disposal repository. This type of simulations deals with highly coupled thermo-hydro-mechanical and chemical (T-H-M-C) processes. A key objective of Alliances is to give the capability for coupling algorithms development between existing codes. The aim of this paper is to present coupling methodology use in the context of this software platform. (author)

  4. Tax responses in platform industries

    DEFF Research Database (Denmark)

    Kind, Hans Jarle; Köthenbürger, Marko; Schjelderup, Guttorm

    2010-01-01

    Two-sided platform firms serve distinct customer groups that are connected through interdependent demand, and include major businesses such as the media industry, banking, and the software industry. A well known result of tax incidence is that consumers of a more heavily taxed good pay a higher...... price and thus buy less of the good. The present paper shows that this result need not hold in a two-sided market. On the contrary, a higher ad valorem tax may lower end-user prices and spur sales. Thus, two-sided platform firms may not at all engage in tax shifting via price increases. We further show...

  5. An Open-Source Based ITS Platform

    DEFF Research Database (Denmark)

    Andersen, Ove; Krogh, Benjamin Bjerre; Torp, Kristian

    2013-01-01

    In this paper, a complete platform used to compute travel times from GPS data is described. Two approaches to computing travel time are proposed one based on points and one based on trips. Overall both approaches give reasonable results compared to existing manual estimated travel times. However......, the trip-based approach requires more GPS data and of a higher quality than the point-based approach. The platform has been completely implemented using open-source software. The main conclusion is that large quantity of GPS data can be managed, with a limited budget and that GPS data is a good source...

  6. Multi-platform Multiplayer RPG Game

    OpenAIRE

    Do Manh, Tuan

    2015-01-01

    Title: Multi-platform Multiplayer RPG Game A multi-platform game, which would be able to run on various devices with Windows 8.1 and Windows Phone 8.1 systems, was created in this work. It was supposed to be a universal game client executable on desktop PCs, notebooks, tablets or mobile phones. The game was supposed to be role-playing game (RPG) with focus on turn-based action combat. In this work, a 3D scene renderer was written which supports rendering simple scenes with objects and animate...

  7. AutoCAD platform customization VBA

    CERN Document Server

    Ambrosius, Lee

    2015-01-01

    Boost productivity and streamline your workflow with expert AutoCAD: VBA programming instruction AutoCAD Platform Customization: VBA is the definitive guide to personalizing AutoCAD and the various programs that run on the AutoCAD platform, including AutoCAD Architecture, Civil 3D, Plant 3D, and more. Written by an Autodesk insider with years of customization and programming experience, this book features detailed discussions backed by real-world examples and easy-to-follow tutorials that illustrate each step in the personalization process. Readers gain expert guidance toward managing layout

  8. Rheem: Enabling Multi-Platform Task Execution

    KAUST Repository

    Agrawal, Divy

    2016-06-16

    Many emerging applications, from domains such as healthcare and oil & gas, require several data processing systems for complex analytics. This demo paper showcases Rheem, a framework that provides multi-platform task execution for such applications. It features a three-layer data processing abstraction and a new query optimization approach for multi-platform settings. We will demonstrate the strengths of Rheem by using real-world scenarios from three different applications, namely, machine learning, data cleaning, and data fusion. © 2016 ACM.

  9. Platform for Distributed 3D Gaming

    OpenAIRE

    Jurgelionis, A; Fechteler, P.; Eisert, P.; Bellotti, F; David, H; Laulajainen, J. P.; Carmichael, R.; Poulopoulos, V.; A. Laikari; Perälä, P.; Gloria, A.; Bouras, C

    2009-01-01

    Video games are typically executed on Windows platforms with DirectX API and require high performance CPUs and graphics hardware. For pervasive gaming in various environments like at home, hotels, or internet cafes, it is beneficial to run games also on mobile devices and modest performance CE devices avoiding the necessity of placing a noisy workstation in the living room or costly computers/consoles in each room of a hotel. This paper presents a new cross-platform approach for distributed 3...

  10. Distributed hash table theory, platforms and applications

    CERN Document Server

    Zhang, Hao; Xie, Haiyong; Yu, Nenghai

    2013-01-01

    This SpringerBrief summarizes the development of Distributed Hash Table in both academic and industrial fields. It covers the main theory, platforms and applications of this key part in distributed systems and applications, especially in large-scale distributed environments. The authors teach the principles of several popular DHT platforms that can solve practical problems such as load balance, multiple replicas, consistency and latency. They also propose DHT-based applications including multicast, anycast, distributed file systems, search, storage, content delivery network, file sharing and c

  11. The ESA earth observation polar platform programme

    Science.gov (United States)

    Rast, M.; Readings, C. J.

    1991-08-01

    The overall scenario of ESA earth observation polar platform program is reviewed with particular attention given to instruments currently being considered for flight on the first European polar platforms. The major objectives of the mission include monitoring the earth's environment on various scales; management and monitoring of the earth's resources; improvement of the service provided to the worldwide operational meteorological community, investigation of the structure and dynamics of the earth's crust and interior. The program encompasses four main elements: an ERS-1 follow-on mission (ERS-2), a solid earth gravity mission (Aristoteles), a Meteosat Second Generation, and a series of polar orbit earth observation missions.

  12. Platform for a better built environment.

    Science.gov (United States)

    Baillie, Jonathan

    2014-08-01

    IHEEM's recently established Architecture and Design of the Built Environment Technical Platform (ADBETP) is now firmly up and running, and, as one of its members, Gary Mortimer, general manager, Facilities & Estates, at NHS Grampian, puts it, is 'determined to bring tangible, positive, and sustainable benefits to the NHS built environment to support the effective delivery of changing clinical needs'. Equally, the Platform hopes its activities will 'add value to IHEEM members, technical professionals in health construction and operational management, and other healthcare professionals working in NHS buildings'.

  13. A mobile and portable trusted computing platform

    Directory of Open Access Journals (Sweden)

    Nepal Surya

    2011-01-01

    Full Text Available Abstract The mechanism of establishing trust in a computing platform is tightly coupled with the characteristics of a specific machine. This limits the portability and mobility of trust as demanded by many emerging applications that go beyond the organizational boundaries. In order to address this problem, we propose a mobile and portable trusted computing platform in a form of a USB device. First, we describe the design and implementation of the hardware and software architectures of the device. We then demonstrate the capabilities of the proposed device by developing a trusted application.

  14. Multisensory platform based on NEC protocol

    Directory of Open Access Journals (Sweden)

    Novaković Đorđe

    2017-01-01

    Full Text Available Multisensory signal acquisition represents one of the main concepts necessary to perform measurements in various industrial and consumer-oriented applications. This paper presents a development platform which provides a data acquisition from multiple sensors. The main module of the platform is the UNIDS-3 development board with PIC18F8520 microcontroller. Data acquisition from the sensors is performed on user demand by remote control. NEC protocol is implemented and IR receiver TSOP31238 is used. The measurement data are sent to a computer, which performs digital data processing, data visualization and data storage. [Project of the Serbian Ministry of Education, Science and Technological Development, Grant no. TR32019

  15. How Important is Export-Platform FDI?

    DEFF Research Database (Denmark)

    Geishecker, Ingo; Nielsen, Jørgen Ulff-Møller; Pawlik, Konrad

    on the respective export performance of Polish industries, we suggest a significant role of export-platform FDI into Poland, while the importance of FDI for vertical integration is limited suggesting that the sourcing of intermediate goods from Poland primarily occurs through arm's-length contractual outsourcing...... instead of in-house sourcing of multinational enterprises. The paper also suggests that over the sample period, where Poland has evolved into a relatively stable economic environment, the role of export-platform FDI has increased significantly.  ...

  16. Platform for Action Guides Chinese Women

    Institute of Scientific and Technical Information of China (English)

    1996-01-01

    THE intense excitement of the United Nations Fourth World Conference on Women (FWCW) waned, with Chinese women realizing the heavy commitments outlined in the Beijing Declaration and the Platform for Action. The documents, which represent the grand goals women have set for realizing their emancipation, will surely be fulfilled through the arduous efforts of women throughout the world. A look back at the past year following the release of the Platform for Action reveals the earnest and effective efforts Chinese women have made for realizing

  17. Traffic information computing platform for big data

    Energy Technology Data Exchange (ETDEWEB)

    Duan, Zongtao, E-mail: ztduan@chd.edu.cn; Li, Ying, E-mail: ztduan@chd.edu.cn; Zheng, Xibin, E-mail: ztduan@chd.edu.cn; Liu, Yan, E-mail: ztduan@chd.edu.cn; Dai, Jiting, E-mail: ztduan@chd.edu.cn; Kang, Jun, E-mail: ztduan@chd.edu.cn [Chang' an University School of Information Engineering, Xi' an, China and Shaanxi Engineering and Technical Research Center for Road and Traffic Detection, Xi' an (China)

    2014-10-06

    Big data environment create data conditions for improving the quality of traffic information service. The target of this article is to construct a traffic information computing platform for big data environment. Through in-depth analysis the connotation and technology characteristics of big data and traffic information service, a distributed traffic atomic information computing platform architecture is proposed. Under the big data environment, this type of traffic atomic information computing architecture helps to guarantee the traffic safety and efficient operation, more intelligent and personalized traffic information service can be used for the traffic information users.

  18. Reconcile: A Coreference Resolution Research Platform

    Energy Technology Data Exchange (ETDEWEB)

    Stoyanov, V; Cardie, C; Gilbert, N; Riloff, E; Buttler, D; Hysom, D

    2009-10-29

    Despite the availability of standard data sets and metrics, approaches to the problem of noun phrase coreference resolution are hard to compare empirically due to the different evaluation setting stemming, in part, from the lack of comprehensive coreference resolution research platforms. In this tech report we present Reconcile, a coreference resolution research platform that aims to facilitate the implementation of new approaches to coreference resolution as well as the comparison of existing approaches. We discuss Reconcile's architecture and give results of running Reconcile on six data sets using four evaluation metrics, showing that Reconcile's performance is comparable to state-of-the-art systems in coreference resolution.

  19. Three-dimensional finite element analysis of platform switched implant

    Science.gov (United States)

    2017-01-01

    PURPOSE The purpose of this study was to analyze the influence of the platform switching concept on an implant system and peri-implant bone using three-dimensional finite element analysis. MATERIALS AND METHODS Two three-dimensional finite element models for wide platform and platform switching were created. In the wide platform model, a wide platform abutment was connected to a wide platform implant. In the platform switching model, the wide platform abutment of the wide platform model was replaced by a regular platform abutment. A contact condition was set between the implant components. A vertical load of 300 N was applied to the crown. The maximum von Mises stress values and displacements of the two models were compared to analyze the biomechanical behavior of the models. RESULTS In the two models, the stress was mainly concentrated at the bottom of the abutment and the top surface of the implant in both models. However, the von Mises stress values were much higher in the platform switching model in most of the components, except for the bone. The highest von Mises values and stress distribution pattern of the bone were similar in the two models. The components of the platform switching model showed greater displacement than those of the wide platform model. CONCLUSION Due to the stress concentration generated in the implant and the prosthodontic components of the platform switched implant, the mechanical complications might occur when platform switching concept is used. PMID:28243389

  20. Free volume under shear

    Science.gov (United States)

    Maiti, Moumita; Vinutha, H. A.; Sastry, Srikanth; Heussinger, Claus

    2015-10-01

    Using an athermal quasistatic simulation protocol, we study the distribution of free volumes in sheared hard-particle packings close to, but below, the random-close packing threshold. We show that under shear, and independent of volume fraction, the free volumes develop features similar to close-packed systems — particles self-organize in a manner as to mimick the isotropically jammed state. We compare athermally sheared packings with thermalized packings and show that thermalization leads to an erasure of these structural features. The temporal evolution in particular the opening-up and the closing of free-volume patches is associated with the single-particle dynamics, showing a crossover from ballistic to diffusive behavior.

  1. Integers annual volume 2013

    CERN Document Server

    Landman, Bruce

    2014-01-01

    ""Integers"" is a refereed online journal devoted to research in the area of combinatorial number theory. It publishes original research articles in combinatorics and number theory. This work presents all papers of the 2013 volume in book form.

  2. Renormalized Volumes with Boundary

    CERN Document Server

    Gover, A Rod

    2016-01-01

    We develop a general regulated volume expansion for the volume of a manifold with boundary whose measure is suitably singular along a separating hypersurface. The expansion is shown to have a regulator independent anomaly term and a renormalized volume term given by the primitive of an associated anomaly operator. These results apply to a wide range of structures. We detail applications in the setting of measures derived from a conformally singular metric. In particular, we show that the anomaly generates invariant (Q-curvature, transgression)-type pairs for hypersurfaces with boundary. For the special case of anomalies coming from the volume enclosed by a minimal hypersurface ending on the boundary of a Poincare--Einstein structure, this result recovers Branson's Q-curvature and corresponding transgression. When the singular metric solves a boundary version of the constant scalar curvature Yamabe problem, the anomaly gives generalized Willmore energy functionals for hypersurfaces with boundary. Our approach ...

  3. Environmental chemistry: Volume A

    Energy Technology Data Exchange (ETDEWEB)

    Yen, T.F.

    1999-08-01

    This is an extensive introduction to environmental chemistry for engineering and chemical professionals. The contents of Volume A include a brief review of basic chemistry prior to coverage of litho, atmo, hydro, pedo, and biospheres.

  4. Generalized Partial Volume

    DEFF Research Database (Denmark)

    Darkner, Sune; Sporring, Jon

    2011-01-01

    Mutual Information (MI) and normalized mutual information (NMI) are popular choices as similarity measure for multimodal image registration. Presently, one of two approaches is often used for estimating these measures: The Parzen Window (PW) and the Generalized Partial Volume (GPV). Their theoret......Mutual Information (MI) and normalized mutual information (NMI) are popular choices as similarity measure for multimodal image registration. Presently, one of two approaches is often used for estimating these measures: The Parzen Window (PW) and the Generalized Partial Volume (GPV...

  5. Reachable volume RRT

    KAUST Repository

    McMahon, Troy

    2015-05-01

    © 2015 IEEE. Reachable volumes are a new technique that allows one to efficiently restrict sampling to feasible/reachable regions of the planning space even for high degree of freedom and highly constrained problems. However, they have so far only been applied to graph-based sampling-based planners. In this paper we develop the methodology to apply reachable volumes to tree-based planners such as Rapidly-Exploring Random Trees (RRTs). In particular, we propose a reachable volume RRT called RVRRT that can solve high degree of freedom problems and problems with constraints. To do so, we develop a reachable volume stepping function, a reachable volume expand function, and a distance metric based on these operations. We also present a reachable volume local planner to ensure that local paths satisfy constraints for methods such as PRMs. We show experimentally that RVRRTs can solve constrained problems with as many as 64 degrees of freedom and unconstrained problems with as many as 134 degrees of freedom. RVRRTs can solve problems more efficiently than existing methods, requiring fewer nodes and collision detection calls. We also show that it is capable of solving difficult problems that existing methods cannot.

  6. City-as-a-Platform: The Rise of Participatory Innovation Platforms in Finnish Cities

    Directory of Open Access Journals (Sweden)

    Ari-Veikko Anttiroiko

    2016-09-01

    Full Text Available This article discusses the idea of city as a platform. The analysis focuses on the forms and implications of citizen involvement in publicly-supported participatory innovation platforms that facilitate urban economic development in the welfare society context. The discussion opens with a review of the smart city discourse, which in the context of economic development policy translates into cities’ need to support innovativeness by creating smart environments. Participatory innovation platform is a prime example of such an environment. The empirical section discusses three cases, those of the Finnish cities of Helsinki, Tampere, and Oulu. The analysis shows that platformization in the first half of the 2010s became a strategic focal area supported by national and EU programs. Platforms are used to support both urban revitalization and economic development, of which the former is based on representative and the latter on instrumental modes of participation. Platforms are well integrated with city governments, even though they vary greatly in terms of organizational forms and scopes. Democratic culture, welfarism, and redistributive policy provide contextual support for platformization by strengthening social inclusion, taming the growth machine, and easing the tensions between pro-growth and anti-growth coalitions.

  7. Information-computational platform for collaborative multidisciplinary investigations of regional climatic changes and their impacts

    Science.gov (United States)

    Gordov, Evgeny; Lykosov, Vasily; Krupchatnikov, Vladimir; Okladnikov, Igor; Titov, Alexander; Shulgina, Tamara

    2013-04-01

    Analysis of growing volume of related to climate change data from sensors and model outputs requires collaborative multidisciplinary efforts of researchers. To do it timely and in reliable way one needs in modern information-computational infrastructure supporting integrated studies in the field of environmental sciences. Recently developed experimental software and hardware platform Climate (http://climate.scert.ru/) provides required environment for regional climate change related investigations. The platform combines modern web 2.0 approach, GIS-functionality and capabilities to run climate and meteorological models, process large geophysical datasets and support relevant analysis. It also supports joint software development by distributed research groups, and organization of thematic education for students and post-graduate students. In particular, platform software developed includes dedicated modules for numerical processing of regional and global modeling results for consequent analysis and visualization. Also run of integrated into the platform WRF and «Planet Simulator» models, modeling results data preprocessing and visualization is provided. All functions of the platform are accessible by a user through a web-portal using common graphical web-browser in the form of an interactive graphical user interface which provides, particularly, capabilities of selection of geographical region of interest (pan and zoom), data layers manipulation (order, enable/disable, features extraction) and visualization of results. Platform developed provides users with capabilities of heterogeneous geophysical data analysis, including high-resolution data, and discovering of tendencies in climatic and ecosystem changes in the framework of different multidisciplinary researches. Using it even unskilled user without specific knowledge can perform reliable computational processing and visualization of large meteorological, climatic and satellite monitoring datasets through

  8. Learning Management Platform for CyberCIEGE

    Science.gov (United States)

    2011-12-01

    Generate Report Function .......................................27 Figure 16. Input and Output Selector Dialog Window...CLE is a platform that allows academic and research collaboration and it is built on open pedagogy and open standard [16]. In those situations...output files, as shown in Figure 16. 28 Figure 16. Input and Output Selector Dialog Window This dialog selects two input mapping files and

  9. JBoss Weld CDI for Java platform

    CERN Document Server

    Finnegan, Ken

    2013-01-01

    This book is a mini tutorial with plenty of code examples and strategies to give you numerous options when building your own applications.""JBoss Weld CDI for Java Platform"" is written for developers who are new to dependency injection. A rudimentary knowledge of Java is required.

  10. International Clinical Trials Registry Platform (ICTRP)

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    @@ Introduction The mission of the WHO Intemational Clinical Trials Registry Platform is to ensure that a complete view of research is accessible to all those involved in health care decision making.This will improve research transparency and will ultimately strengthen tha validity and value of the scientific evidence base.The registration of all interventional trials is a scientific, ethical and moral responsibility.

  11. Cross-platform wireless sensor network development

    DEFF Research Database (Denmark)

    Hansen, Morten Tranberg; Kusy, Branislav

    -source development environment that takes a holistic approach to implementing sensor network applications. Users build applications using a drag-and-drop visual programming language Open Blocks, a language that Google selected for its App Inventor for Android. Tinylnventor uses cross-platform programming concepts...

  12. Rapid Prototyping Platform for Robotics Applications

    Science.gov (United States)

    Hwang, Kao-Shing; Hsiao, Wen-Hsu; Shing, Gaung-Ting; Chen, Kim-Joan

    2011-01-01

    For the past several years, a team in the Department of Electrical Engineering (EE), National Chung Cheng University, Taiwan, has been establishing a pedagogical approach to embody embedded systems in the context of robotics. To alleviate the burden on students in the robotics curriculum in their junior and senior years, a training platform on…

  13. A Platform for Learning Internet of Things

    Science.gov (United States)

    Bogdanovic, Zorica; Simic, Konstantin; Milutinovic, Miloš; Radenkovic, Božidar; Despotovic-Zrakic, Marijana

    2014-01-01

    This paper presents a model for conducting Internet of Things (IoT) classes based on a web-service oriented cloud platform. The goal of the designed model is to provide university students with knowledge about IoT concepts, possibilities, and business models, and allow them to develop basic system prototypes using general-purpose microdevices and…

  14. 2009 Thermochemical Conversion Platform Review Report

    Energy Technology Data Exchange (ETDEWEB)

    Ferrell, John [Office of Energy Efficiency and Renewable Energy (EERE), Washington, DC (United States)

    2009-12-01

    This document summarizes the recommendations and evaluations provided by an independent external panel of experts at the U.S. Department of Energy Biomass Program’s Thermochemical Conversion platform review meeting, held on April 14-16, 2009, at the Sheraton Denver Downtown, Denver, Colorado.

  15. Mobile platform for acoustic mine detection applications

    Science.gov (United States)

    Libbey, Brad; Fenneman, Douglas; Burns, Brian

    2005-06-01

    Researchers in academia have successfully demonstrated acoustic landmine detection techniques. These typically employ acoustic or seismic sources to induce vibration in the mine/soil system, and use vibration sensors such as laser vibrometers or geophones to measure the resultant surface motion. These techniques exploit the unique mechanical properties of landmines to discriminate the vibration response of a buried mine from an off-target measurement. The Army requires the ability to rapidly and reliably scan an area for landmines and is developing a mobile platform at NVESD to meet this requirement. The platform represents an initial step toward the implementation of acoustic mine detection technology on a representative field vehicle. The effort relies heavily on the acoustic mine detection cart system developed by researchers at the University of Mississippi and Planning Systems, Inc. The NVESD platform consists of a John Deere E-gator configured with a robotic control system to accurately position the vehicle. In its present design, the E-gator has been outfitted with an array of laser vibrometers and a bank of loudspeakers. Care has been taken to ensure that the vehicle"s mounting hardware and data acquisition algorithms are sufficiently robust to accommodate the implementation of other sensor modalities. A thorough discussion of the mobile platform from its inception to its present configuration will be provided. Specific topics to be addressed include the vehicle"s control and data acquisition systems. Preliminary results from acoustic mine detection experiments will also be presented.

  16. Collapse of modern carbonate platform margins

    Energy Technology Data Exchange (ETDEWEB)

    Mullins, H.T.; Hine, A.C.; Gardulski, A.

    1985-01-01

    Modern carbonate platform margins in the Florida-Bahama region have been viewed as depositional or constructional features. However, recent studies have shown that carbonate escarpments, such as the Blake-Bahama and West Florida Escarpments, are erosional in origin where the platform margins have a scalloped or horse-shoe shape. Seismic reflection data from one of these crescentic features along the west Florida platform margin indicate that it originated by large scale gravity collapse (slump). This collapse structure extends for at least 120 km along the margin and has removed about 350 m of strata as young as early Neogene. Although at least three generations of slope failure are recognized, catastrophic collapse appears to have occurred in the mid-Miocene. Gravitational instability due to high rates of sediment accumulation may have been the triggering mechanism. These data suggest that submarine slumping is an important process in the retreat of limestone escarpments and in the generation of carbonate megabreccia debris flows. Scalloped platform margins occur on satellite images of northern Exuma Sound and Columbus Basin in the Bahamas. The authors suggest that large-scale submarine slumping can cause elongation of structurally controlled intraplatform basins (Exuma South), and produce anomalous horse-shoe shaped basins (Columbus Basin) by mega-collapse processes.

  17. Platform Technology for Developing Purification Processes

    NARCIS (Netherlands)

    Eppink, M.H.M.; Schreurs, R.; Gijsen, A.; Verhoeven, K.

    2009-01-01

    To shorten time to market for new therapeutic proteins, new and fast methods, such as high throughput screening, are needed to speed up downstream processing. The platform technology discussed in this article includes a structural approach that can be used as a general procedure to purify therapeuti

  18. FDI as an Export-Platform

    DEFF Research Database (Denmark)

    Hajderllari, Luljeta; Karantininis, Konstantinos; Lawson, Lartey Godwin

    towards countries with large exports of agri-food, thereby supporting the hypothesis that FDI is used as an export-platform. FDI is coupled with high exports from Denmark, probably of raw or semi-processed food products for further processing and exports. We also find that FDI is higher in countries...

  19. Designing Polymeric Microfluidic Platforms for Biomedical Applications

    DEFF Research Database (Denmark)

    Vedarethinam, Indumathi

    Micro- and Nanotechnology have the potential to offer a smart solution for diagnostics and academia research with rapid, low cost, robust analysis systems to facilitate biological analyses. New, high throughput microfluidic platforms have the potential to surpass in performance the conventional a...

  20. On designing a pervasive mobile learning platform

    Directory of Open Access Journals (Sweden)

    Teemu H. Laine

    2010-12-01

    Full Text Available This article presents the features, design and architecture of the Myst pervasive game platform that has been applied in creating pervasive mobile learning games in various contexts such as science festivals and museums in Finland. Based on our experiences with the development, we draw a set of design principles for creating successfully a pervasive game platform that can be easily ported to various contexts. These principles advocate openness, flexibility, interaction models, connections to the outside world, and participatory design of the game content. In the evaluation part we present preliminary results of tests conducted in Finland at the SciFest 2008 festival in Joensuu and at the Museum of Technology in Helsinki. The results suggest that games built with the Myst platform are particularly suitable for children and young adults, and these games motivate players to interact with the environment and help to learn by discovering new things. The Myst platform has clearly potential for similar success in other environments due to easy portability and extensibility.

  1. A gimbal platform stabilization for topographic applications

    Energy Technology Data Exchange (ETDEWEB)

    Michele, Mangiameli, E-mail: michele.mangiameli@dica.unict.it; Giuseppe, Mussumeci [Dept. of Civil Engineering and Architecture, University of Catania, Catania (Italy)

    2015-03-10

    The aim of this work is the stabilization of a Gimbal platform for optical sensors acquisitions in topographic applications using mobile vehicles. The stabilization of the line of sight (LOS) consists in tracking the command velocity in presence of nonlinear noise due to the external environment. The hardware architecture is characterized by an Ardupilot platform that allows the control of both the mobile device and the Gimbal. Here we developed a new approach to stabilize the Gimbal platform, which is based on neural network. For the control system, we considered a plant that represents the transfer function of the servo system control model for an inertial stabilized Gimbal platform. The transductor used in the feed-back line control is characterized by the Rate Gyro transfer function installed onboard of Ardupilot. For the simulation and investigation of the system performance, we used the Simulink tool of Matlab. Results show that the hardware/software approach is efficient, reliable and cheap for direct photogrammetry, as well as for general purpose applications using mobile vehicles.

  2. PROBA-V Mission Exploitation Platform

    Directory of Open Access Journals (Sweden)

    Erwin Goor

    2016-07-01

    Full Text Available As an extension of the PROBA-Vegetation (PROBA-V user segment, the European Space Agency (ESA, de Vlaamse Instelling voor Technologisch Onderzoek (VITO, and partners TRASYS and Spacebel developed an operational Mission Exploitation Platform (MEP to drastically improve the exploitation of the PROBA-V Earth Observation (EO data archive, the archive from the historical SPOT-VEGETATION mission, and derived products by researchers, service providers, and thematic users. The analysis of the time series of data (petabyte range is addressed, as well as the large scale on-demand processing of the complete archive, including near real-time data. The platform consists of a private cloud environment, a Hadoop-based processing environment and a data manager. Several applications are released to the users, e.g., a full resolution viewing service, a time series viewer, pre-defined on-demand processing chains, and virtual machines with powerful tools and access to the data. After an initial release in January 2016 a research platform was deployed gradually, allowing users to design, debug, and test applications on the platform. From the PROBA-V MEP, access to, e.g., Sentinel-2 and Sentinel-3 data will be addressed as well.

  3. Multipurpose Platform for Electronic Currency System

    Directory of Open Access Journals (Sweden)

    Andreea Magdalena Dae

    2014-12-01

    Full Text Available Nowadays, there are multiple solutions for exchanging electronic currencies which will most probably replace physical money. This paper presents a platform for electronic currency system implemented within a Java smart card for accessing different types of products or services. The user interacts with an “electronic currency bank” and with a merchant through a secure protocol.

  4. Xamarin cross-platform application development

    CERN Document Server

    Peppers, Jonathan

    2015-01-01

    If you are a developer with experience in C# and are just getting into mobile development, this is the book for you. If you have experience with desktop applications or the Web, this book will give you a head start on cross-platform development.

  5. Estimation of Errors in Force Platform Data

    Science.gov (United States)

    Psycharakis, Stelios G.; Miller, Stuart

    2006-01-01

    Force platforms (FPs) are regularly used in the biomechanical analysis of sport and exercise techniques, often in combination with image-based motion analysis. Force time data, particularly when combined with joint positions and segmental inertia parameters, can be used to evaluate the effectiveness of a wide range of movement patterns in sport…

  6. Rapid world modelling from a mobile platform

    Energy Technology Data Exchange (ETDEWEB)

    Barry, R.E.; Jones, J.P. [Oak Ridge National Lab., TN (United States); Little, C.Q. [Sandia National Labs., Albuquerque, NM (United States); Wilson, C.W.

    1997-04-01

    The ability to successfully use and interact with a computerized world model is dependent on the ability to create an accurate world model. The goal of this project was to develop a prototype system to remotely deploy sensors into a workspace, collect surface information, and rapidly build an accurate world model of that workspace. A key consideration was that the workspace areas are typically hazardous environments, where it is difficult or impossible for humans to enter. Therefore, the system needed to be fully remote, with no external connections. To accomplish this goal, an electric, mobile platform with battery power sufficient for both the platform and sensor electronics was procured and 3D range sensors were deployed on the platform to capture surface data within the workspace. A radio Ethernet connection was used to provide communications to the vehicle and all on-board electronics. Video from on-board cameras was also transmitted to the base station and used to teleoperate the vehicle. Range data generated by the on-board 3D sensors was transformed into surface maps, or models. Registering the sensor location to a consistent reference frame as the platform moved through the workspace allowed construction of a detailed 3D world model of the extended workspace.

  7. Verkeer in het Platform Integrale Energieanalyse (PIE)

    NARCIS (Netherlands)

    Brink RMM van den; Feimann PFL; LAE

    2003-01-01

    Dit rapport beschrijft het deelmodel Verkeer en Vervoer (PIE-VeV) van het Platform voor Integrale Energie- en emissieverkenningen (PIE). PIE is door de doelgroep Energie ontwikkeld in nauwe samenwerking met het ECN en is een integratieplatform dat de grootte en de samenstelling van de vraag naar

  8. Using the MVC architecture on . NET platform

    OpenAIRE

    Ježek, David

    2011-01-01

    This thesis deals with usage of MVC (Model View Controller) technology in web development on ASP.NET platform from Microsoft. Mainly it deals with latest version of framework ASP.NET MVC 3. First part describes MVC architecture and the second describes usage of MVC in certain parts of web application an comparing with PHP.

  9. Simultanuous Location and Mapping - A Simulation Platform

    DEFF Research Database (Denmark)

    Sejerøe, Thomas Hanefeld; Ravn, Ole; Poulsen, Niels Kjølstad

    2005-01-01

    In this paper we present a simulation platform for evaluate methods for simultaneous location and mapping. The platfor is based on The KALMTOOL 2 toolbox which is a set of MATLAB tools for state estimation for nonlinear systems. The toolbox contains functions for extended Kalman filtering as well...

  10. Building National Innovation Platform in China

    DEFF Research Database (Denmark)

    Li, Jizhen; Deng, Quwen; Sørensen, Olav Jull

    2011-01-01

    The focus of the article is the "national innovation platform" that are being build in China to enhance interaction between stakeholders and encourage knowledge flows. The textile industry is used as an example to discuss suitablity and lay a foundation for theoretical reflections of the new...

  11. Simulation Platform for Vision Aided Inertial Navigation

    Science.gov (United States)

    2014-09-18

    canyons, indoors or underground. It is also possible for a GPS signal to be jammed. This weakness motivates the development of alternate navigation ...Johnson, E. N., Magree, D., Wu, A., & Shein, A. (2013). "GPS‐Denied Indoor and Outdoor Monocular Vision Aided Navigation and Control of Unmanned...SIMULATION PLATFORM FOR VISION AIDED INERTIAL NAVIGATION THESIS SEPTEMBER 2014 Jason Gek

  12. 2009 Biochemical Conversion Platform Review Report

    Energy Technology Data Exchange (ETDEWEB)

    Ferrell, John [Office of Energy Efficiency and Renewable Energy (EERE), Washington, DC (United States)

    2009-12-01

    This document summarizes the recommendations and evaluations provided by an independent external panel of experts at the U.S. Department of Energy Biomass Program’s Biochemical Conversion platform review meeting, held on April 14-16, 2009, at the Sheraton Denver Downtown, Denver, Colorado.

  13. 2009 Integrated Biorefinery Platform Review Report

    Energy Technology Data Exchange (ETDEWEB)

    Ferrell, John [Office of Energy Efficiency and Renewable Energy (EERE), Washington, DC (United States)

    2009-12-01

    This document summarizes the recommendations and evaluations provided by an independent external panel of experts at the U.S. Department of Energy Biomass Program‘s Integrated Biorefinery (IBR) platform review meeting, held on February 18–19, 2009, at the Westin National Harbor, National Harbor, Maryland.

  14. Cross-platform wireless sensor network development

    DEFF Research Database (Denmark)

    Hansen, Morten Tranberg; Kusy, Branislav

    -source development environment that takes a holistic approach to implementing sensor network applications. Users build applications using a drag-and-drop visual programming language Open Blocks, a language that Google selected for its App Inventor for Android. Tinylnventor uses cross-platform programming concepts...

  15. Platform Precision Autopilot Overview and Mission Performance

    Science.gov (United States)

    Strovers, Brian K.; Lee, James A.

    2009-01-01

    The Platform Precision Autopilot is an instrument landing system-interfaced autopilot system, developed to enable an aircraft to repeatedly fly nearly the same trajectory hours, days, or weeks later. The Platform Precision Autopilot uses a novel design to interface with a NASA Gulfstream III jet by imitating the output of an instrument landing system approach. This technique minimizes, as much as possible, modifications to the baseline Gulfstream III jet and retains the safety features of the aircraft autopilot. The Platform Precision Autopilot requirement is to fly within a 5-m (16.4-ft) radius tube for distances to 200 km (108 nmi) in the presence of light turbulence for at least 90 percent of the time. This capability allows precise repeat-pass interferometry for the Unmanned Aerial Vehicle Synthetic Aperture Radar program, whose primary objective is to develop a miniaturized, polarimetric, L-band synthetic aperture radar. Precise navigation is achieved using an accurate differential global positioning system developed by the Jet Propulsion Laboratory. Flight-testing has demonstrated the ability of the Platform Precision Autopilot to control the aircraft within the specified tolerance greater than 90 percent of the time in the presence of aircraft system noise and nonlinearities, constant pilot throttle adjustments, and light turbulence.

  16. Building National Innovation Platform in China

    DEFF Research Database (Denmark)

    Li, Jizhen; Deng, Quwen; Sørensen, Olav Jull

    2011-01-01

    The focus of the article is the "national innovation platform" that are being build in China to enhance interaction between stakeholders and encourage knowledge flows. The textile industry is used as an example to discuss suitablity and lay a foundation for theoretical reflections of the new...

  17. Development of Industrial Yeast Platform Strains

    DEFF Research Database (Denmark)

    Bergdahl, Basti; Dato, Laura; Förster, Jochen

    2014-01-01

    frequently encounter high substrate concentrations, low pH, high temperatures and various inhibitory compounds originating either from the raw material used or from cellular metabolism. The aim of this research project is to develop robust platform strains of Saccharomyces cerevisiae based on industrial...

  18. Towards a Market Entry Framework for Digital Payment Platforms

    DEFF Research Database (Denmark)

    Kazan, Erol; Damsgaard, Jan

    2016-01-01

    This study presents a framework to understand and explain the design and configuration of digital payment platforms and how these platforms create conditions for market entries. By embracing the theoretical lens of platform envelopment, we employed a multiple and comparative-case study...... in a European setting by using our framework as an analytical lens to assess market-entry conditions. We found that digital payment platforms have acquired market entry capabilities, which is achieved through strategic platform design (i.e., platform development and service distribution) and technology design...... (i.e., issuing evolutionary and revolutionary payment instruments). The studied cases reveal that digital platforms leverage payment services as a mean to bridge and converge core and adjacent platform markets. In so doing, platform envelopment strengthens firms’ market position in their respective...

  19. Turbine blade and non-integral platform with pin attachment

    Energy Technology Data Exchange (ETDEWEB)

    Campbell, Christian Xavier; Eng, Darryl; Marra, John J.

    2016-08-02

    Platforms (36, 38) span between turbine blades (23, 24, 25) on a disk (32). Each platform may be individually mounted to the disk by a pin attachment (42). Each platform (36) may have a rotationally rearward edge portion (50) that underlies a forward portion (45) of the adjacent platform (38). This limits centrifugal bending of the rearward portion of the platform, and provides coolant sealing. The rotationally forward edge (44A, 44B) of the platform overlies a seal element (51) on the pressure side (28) of the forwardly adjacent blade, and does not underlie a shelf on that blade. The pin attachment allows radial mounting of each platform onto the disk via tilting (60) of the platform during mounting to provide mounting clearance for the rotationally rearward edge portion (50). This facilitates quick platform replacement without blade removal.

  20. Towards a Market Entry Framework for Digital Payment Platforms

    DEFF Research Database (Denmark)

    Kazan, Erol; Damsgaard, Jan

    2016-01-01

    (i.e., issuing evolutionary and revolutionary payment instruments). The studied cases reveal that digital platforms leverage payment services as a mean to bridge and converge core and adjacent platform markets. In so doing, platform envelopment strengthens firms’ market position in their respective......This study presents a framework to understand and explain the design and configuration of digital payment platforms and how these platforms create conditions for market entries. By embracing the theoretical lens of platform envelopment, we employed a multiple and comparative-case study...... in a European setting by using our framework as an analytical lens to assess market-entry conditions. We found that digital payment platforms have acquired market entry capabilities, which is achieved through strategic platform design (i.e., platform development and service distribution) and technology design...

  1. A Comparative Study on Hardware Platforms for Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    Thang Vu Chien

    2012-01-01

    Full Text Available Recently, Wireless Sensor Networks (WSNs attract a great deal of research attention, and are envisioned to support a variety of applications, including building monitoring, environment control, wild-life habitat monitoring, forest fire detection, industry automation, military, security, and health-care. Over the years, we have seen a variety of hardware platforms for WSNs to facilitate developing WSN applications. In this paper, we provide a comprehensive review of existing hardware platforms for WSNs. We first present the hardware architecture of a wireless sensor node. We then survey the major hardware platforms for WSNs and present a comparison of these hardware platforms. Finally we present some recommendations from the perspectives of hardware platform developers and hardware platform users. The authors hope that making information about existing hardware platforms will assist researchers working in this area to appreciate the diversity of platforms available to them and to help them select the most appropriate platform for their purposes.

  2. Turbine blade and non-integral platform with pin attachment

    Science.gov (United States)

    Campbell, Christian X; Eng, Darryl; Marra, John J

    2015-01-27

    Platforms (36, 38) span between turbine blades (23, 24, 25) on a disk (32). Each platform may be individually mounted to the disk by a pin attachment (42). Each platform (36) may have a rotationally rearward edge portion (50) that underlies a forward portion (45) of the adjacent platform (38). This limits centrifugal bending of the rearward portion of the platform, and provides coolant sealing. The rotationally forward edge (44A, 44B) of the platform overlies a seal element (51) on the pressure side (28) of the forwardly adjacent blade, and does not underlie a shelf on that blade. The pin attachment allows radial mounting of each platform onto the disk via tilting (60) of the platform during mounting to provide mounting clearance for the rotationally rearward edge portion (50). This facilitates quick platform replacement without blade removal.

  3. Shielding considerations for the small animal radiation research platform (SARRP).

    Science.gov (United States)

    Sayler, Elaine; Dolney, Derek; Avery, Stephen; Koch, Cameron

    2013-05-01

    The Small Animal Radiation Research Platform (SARRP) is a commercially available platform designed to deliver conformal, image-guided radiation to small animals using a dual-anode kV x-ray source. At the University of Pennsylvania, a free-standing 2 m enclosure was designed to shield the SARRP according to federal code regulating cabinet x-ray systems. The initial design consisted of 4.0-mm-thick lead for all secondary barriers and proved wholly inadequate. Radiation levels outside the enclosure were 15 times higher than expected. Additionally, the leakage appeared to be distributed broadly within the enclosure, so concern arose that a subject might receive significant doses outside the intended treatment field. Thus, a detailed analysis was undertaken to identify and block all sources of leakage. Leakage sources were identified by Kodak X-OmatV (XV) film placed throughout the enclosure. Radiation inside the enclosure was quantified using Gafchromic film. Outside the enclosure, radiation was measured using a survey meter. Sources of leakage included (1) an unnecessarily broad beam exiting the tube, (2) failure of the secondary collimator to confine the primary beam entirely, (3) scatter from the secondary collimator, (4) lack of beam-stop below the treatment volume, and (5) incomplete shielding of the x-ray tube. The exit window was restricted, and a new collimator was designed to address problems (1-3). A beam-stop and additional tube shielding were installed. These modifications reduced internal scatter by more than 100-fold. Radiation outside the enclosure was reduced to levels compliant with federal regulations, provided the SARRP is operated using tube potentials of 175 kV or less. In addition, these simple and relatively inexpensive modifications eliminate the possibility of exposing a larger animal (such as a rat) to significant doses outside the treatment field.

  4. High precipitation rate in a Middle Triassic carbonate platform: Implications on the relationship between seawater saturation state and carbonate production

    Science.gov (United States)

    Franceschi, Marco; Preto, Nereo; Marangon, Alessandro; Gattolin, Giovanni; Meda, Marco

    2016-06-01

    Three-dimensional geological modeling of the Middle Triassic Latemar carbonate platform is coupled with facies modal analysis to estimate its carbonate precipitation rate (G). The 3D model, strongly constrained by field data, encompasses a specific stratigraphic interval of the platform, bounded by two isochronous surfaces. Modal analysis of thin sections allows estimating the proportion of syndepositional vs postdepositional carbonate in the facies associations of the platform. This, together with the 3D facies distribution in the model that takes into account lateral and vertical facies variability, permits to calculate the volumes of syndepositional carbonate preserved at Latemar between the two considered isochrones. Given the peculiar characteristics of the platform, that does not show evidences of strong dissolution processes or large carbonate mass loss through export in the nearby basins, results can be used to estimate the average precipitation rate of the platform in the considered time interval. This estimate allows discussion in relation to models of ocean water saturation state (Ω) with respect to carbonates in the geological past, and comparison to the calculated precipitation rates of modern tropical coral reef ecosystems at global and reef scale. A high G value is found at Latemar and represents the first empirical confirmation that, in the Triassic, extremes in Ω may have triggered high carbonate precipitation in shallow water settings; moreover, comparison to modern reefs points to a possible common relationship that may link seawater Ω and precipitation rate in carbonate platform ecosystems through geological time.

  5. Knowledge Discovery for Smart Grid Operation, Control, and Situation Awareness -- A Big Data Visualization Platform

    Energy Technology Data Exchange (ETDEWEB)

    Gu, Yi; Jiang, Huaiguang; Zhang, Yingchen; Zhang, Jun Jason; Gao, Tianlu; Muljadi, Eduard

    2016-11-21

    In this paper, a big data visualization platform is designed to discover the hidden useful knowledge for smart grid (SG) operation, control and situation awareness. The spawn of smart sensors at both grid side and customer side can provide large volume of heterogeneous data that collect information in all time spectrums. Extracting useful knowledge from this big-data poll is still challenging. In this paper, the Apache Spark, an open source cluster computing framework, is used to process the big-data to effectively discover the hidden knowledge. A high-speed communication architecture utilizing the Open System Interconnection (OSI) model is designed to transmit the data to a visualization platform. This visualization platform uses Google Earth, a global geographic information system (GIS) to link the geological information with the SG knowledge and visualize the information in user defined fashion. The University of Denver's campus grid is used as a SG test bench and several demonstrations are presented for the proposed platform.

  6. Virtual Distances Methodology as Verification Technique for AACMMs with a Capacitive Sensor Based Indexed Metrology Platform.

    Science.gov (United States)

    Acero, Raquel; Santolaria, Jorge; Brau, Agustin; Pueo, Marcos

    2016-11-18

    This paper presents a new verification procedure for articulated arm coordinate measuring machines (AACMMs) together with a capacitive sensor-based indexed metrology platform (IMP) based on the generation of virtual reference distances. The novelty of this procedure lays on the possibility of creating virtual points, virtual gauges and virtual distances through the indexed metrology platform's mathematical model taking as a reference the measurements of a ball bar gauge located in a fixed position of the instrument's working volume. The measurements are carried out with the AACMM assembled on the IMP from the six rotating positions of the platform. In this way, an unlimited number and types of reference distances could be created without the need of using a physical gauge, therefore optimizing the testing time, the number of gauge positions and the space needed in the calibration and verification procedures. Four evaluation methods are presented to assess the volumetric performance of the AACMM. The results obtained proved the suitability of the virtual distances methodology as an alternative procedure for verification of AACMMs using the indexed metrology platform.

  7. UAV multirotor platform for accurate turbulence measurements in the atmosphere

    Science.gov (United States)

    Carbajo Fuertes, Fernando; Wilhelm, Lionel; Sin, Kevin Edgar; Hofer, Matthias; Porté-Agel, Fernando

    2017-04-01

    One of the most challenging tasks in atmospheric field studies for wind energy is to obtain accurate turbulence measurements at any location inside the region of interest for a wind farm study. This volume would ideally include from several hundred meters to several kilometers around it and from ground height to the top of the boundary layer. An array of meteorological masts equipped with several sonic anemometers to cover all points of interest would be the best in terms of accuracy and data availability, but it is an obviously unfeasible solution. On the other hand, the evolution of wind LiDAR technology allows to measure at any point in space but unfortunately it involves two important limitations: the first one is the relatively low spatial and temporal resolution when compared to a sonic anemometer and the second one is the fact that the measurements are limited to the velocity component parallel to the laser beam (radial velocity). To overcome the aforementioned drawbacks, a UAV multirotor platform has been developed. It is based on a state-of-the-art octocopter with enough payload to carry laboratory-grade instruments for the measurement of time-resolved atmospheric pressure, three-component velocity vector and temperature; and enough autonomy to fly from 10 to 20 minutes, which is a standard averaging time in most atmospheric measurement applications. The UAV uses a gyroscope, an accelerometer, a GPS and an algorithm has been developed and integrated for the correction of any orientation and movement. This UAV platform opens many possibilities for the study of features that have been almost exclusively studied until now in wind tunnel such as wind turbine blade tip vortex characteristics, near-wake to far-wake transition, momentum entrainment from the higher part of the boundary layer in wind farms, etc. The validation of this new measurement technique has been performed against sonic anemometry in terms of wind speed and temperature time series as well as

  8. Silicon nanomaterials platform for bioimaging, biosensing, and cancer therapy.

    Science.gov (United States)

    Peng, Fei; Su, Yuanyuan; Zhong, Yiling; Fan, Chunhai; Lee, Shuit-Tong; He, Yao

    2014-02-18

    Silicon nanomaterials are an important class of nanomaterials with great potential for technologies including energy, catalysis, and biotechnology, because of their many unique properties, including biocompatibility, abundance, and unique electronic, optical, and mechanical properties, among others. Silicon nanomaterials are known to have little or no toxicity due to favorable biocompatibility of silicon, which is an important precondition for biological and biomedical applications. In addition, huge surface-to-volume ratios of silicon nanomaterials are responsible for their unique optical, mechanical, or electronic properties, which offer exciting opportunities for design of high-performance silicon-based functional nanoprobes, nanosensors, and nanoagents for biological analysis and detection and disease treatment. Moreover, silicon is the second most abundant element (after oxygen) on earth, providing plentiful and inexpensive resources for large-scale and low-cost preparation of silicon nanomaterials for practical applications. Because of these attractive traits, and in parallel with a growing interest in their design and synthesis, silicon nanomaterials are extensively investigated for wide-ranging applications, including energy, catalysis, optoelectronics, and biology. Among them, bioapplications of silicon nanomaterials are of particular interest. In the past decade, scientists have made an extensive effort to construct a silicon nanomaterials platform for various biological and biomedical applications, such as biosensors, bioimaging, and cancer treatment, as new and powerful tools for disease diagnosis and therapy. Nonetheless, there are few review articles covering these important and promising achievements to promote the awareness of development of silicon nanobiotechnology. In this Account, we summarize recent representative works to highlight the recent developments of silicon functional nanomaterials for a new, powerful platform for biological and

  9. Floating substructure flexibility of large-volume 10MW offshore wind turbine platforms in dynamic calculations

    DEFF Research Database (Denmark)

    Borg, Michael; Hansen, Anders Melchior; Bredmose, Henrik

    2016-01-01

    to the extent that it becomes relevant to include in addition to the standard rigid body substructure modes which are typically described through linear radiation-diffraction theory. This paper describes a method for the inclusion of substructural flexibility in aero-hydro-servo-elastic dynamic simulations......Designing floating substructures for the next generation of 10MW and larger wind turbines has introduced new challenges in capturing relevant physical effects in dynamic simulation tools. In achieving technically and economically optimal floating substructures, structural flexibility may increase...

  10. Cross-platform learning: on the nature of children's learning from multiple media platforms.

    Science.gov (United States)

    Fisch, Shalom M

    2013-01-01

    It is increasingly common for an educational media project to span several media platforms (e.g., TV, Web, hands-on materials), assuming that the benefits of learning from multiple media extend beyond those gained from one medium alone. Yet research typically has investigated learning from a single medium in isolation. This paper reviews several recent studies to explore cross-platform learning (i.e., learning from combined use of multiple media platforms) and how such learning compares to learning from one medium. The paper discusses unique benefits of cross-platform learning, a theoretical mechanism to explain how these benefits might arise, and questions for future research in this emerging field.

  11. Spintronic microfluidic platform for biomedical and environmental applications

    Science.gov (United States)

    Cardoso, F. A.; Martins, V. C.; Fonseca, L. P.; Germano, J.; Sousa, L. A.; Piedade, M. S.; Freitas, P. P.

    2010-09-01

    Faster, more sensitive and easy to operate biosensing devices still are a need at important areas such as biomedical diagnostics, food control and environmental monitoring. Recently, spintronic-devices have emerged as a promising alternative to the existent technologies [1-3]. A number of advantages, namely high sensitivity, easy integration, miniaturization, scalability, robustness and low cost make these devices potentially capable of responding to the existent technological need. In parallel, the field of microfluidics has shown great advances [4]. Microfluidic systems allow the analysis of small sample volumes (from micro- down to pico-liters), often by automate sample processing with the ability to integrate several steps into a single device (analyte amplification, concentration, separation and/or labeling), all in a reduced assay time (minutes to hours) and affordable cost. The merging of these two technologies, magnetoresistive biochips and microfluidics, will enable the development of highly competitive devices. This work reports the integration of a magnetoresistive biochip with a microfluidic system inside a portable and autonomous electronic platform aiming for a fully integrated device. A microfluidic structure fabricated in polydimethylsiloxane with dimensions of W: 0.5mm, H: 0.1mm, L: 10mm, associated to a mechanical system to align and seal the channel by pressure is presented (Fig. 1) [5]. The goal is to perform sample loading and transportation over the chip and simultaneously control the stringency and uniformity of the wash-out process. The biochip output is acquired by an electronic microsystem incorporating the circuitry to control, address and read-out the 30 spin-valve sensors sequentially (Fig. 1) [2]. This platform is being applied to the detection of water-borne microbial pathogens (e.g. Salmonella and Escherichia coli) and genetic diseases diagnosis (e.g. cystic fibrosis) through DNA hybridization assays. Open chamber measurements were

  12. Comparisons of the suture zones along a geotraverse from the Scythian Platform to the Arabian Platform

    Directory of Open Access Journals (Sweden)

    Ali Yılmaz

    2014-11-01

    Full Text Available The area from the Greater Caucasus to the southeast Turkey is characterized and shaped by several major continental blocks. These are Scythian Platform, Pontian–Transcaucasus Continent-Arc System (PTCAS, the Anatolian–Iranian and the Arabian Platforms. The aim of this paper is to define these continental blocks and describe and also compare their boundary relationships along the suture zones. The Scythian Platform displays the evidence of the Hercynian and Alpine orogens. This platform is separated from the PTCAS by the Greater Caucasus Suture Zone. The incipient collision began along this suture zone before middle–late Carboniferous whereas the final collision occurred before Oligocene. The PTCAS can be divided into four structural units: (1 the Georgian Block – northern part of the Pontian–Transcaucasian island-arc, (2 the southern and eastern Black Sea Coast–Adjara–Trialeti Unit, (3 the Artvin–Bolnisi Unit, comprising the northern part of the southern Transcaucasus, and (4 the Imbricated Bayburt–Garabagh Unit. The PTCAS could be separated from the Anatolian–Iranian Platform by the North Anatolian–Lesser Caucasus Suture (NALCS zone. The initial collision was developed in this suture zone during Senonian–early Eocene and final collision before middle Eocene or Oligocene–Miocene. The Anatolian–Iranian Platform (AIP is made up of the Tauride Platform and its metamorphic equivalents together with Iranian Platform. It could be separated from the Arabian Platform by the Southeastern Anatolian Suture (SEAS zone. The collision ended before late Miocene along this suture zone. The southernmost continental block of the geotraverse is the Arabian Platform, which constitutes the northern part of the Arabian–African Plate. This platform includes a sequence from the Precambrian felsic volcanic and clastic rocks to the Campanian–early Maastrichtian flyschoidal clastics. All the suture zones include MORB and SSZ

  13. Volumes of chain links

    CERN Document Server

    Kaiser, James; Rollins, Clint

    2011-01-01

    Agol has conjectured that minimally twisted n-chain links are the smallest volume hyperbolic manifolds with n cusps, for n at most 10. In his thesis, Venzke mentions that these cannot be smallest volume for n at least 11, but does not provide a proof. In this paper, we give a proof of Venzke's statement. The proof for n at least 60 is completely rigorous. The proof for n between 11 and 59 uses a computer calculation, and can be made rigorous for manifolds of small enough complexity, using methods of Moser and Milley. Finally, we prove that the n-chain link with 2m or 2m+1 half-twists cannot be the minimal volume hyperbolic manifold with n cusps, provided n is at least 60 or |m| is at least 8, and we give computational data indicating this remains true for smaller n and |m|.

  14. Publishing Platform for Scientific Software - Lessons Learned

    Science.gov (United States)

    Hammitzsch, Martin; Fritzsch, Bernadette; Reusser, Dominik; Brembs, Björn; Deinzer, Gernot; Loewe, Peter; Fenner, Martin; van Edig, Xenia; Bertelmann, Roland; Pampel, Heinz; Klump, Jens; Wächter, Joachim

    2015-04-01

    Scientific software has become an indispensable commodity for the production, processing and analysis of empirical data but also for modelling and simulation of complex processes. Software has a significant influence on the quality of research results. For strengthening the recognition of the academic performance of scientific software development, for increasing its visibility and for promoting the reproducibility of research results, concepts for the publication of scientific software have to be developed, tested, evaluated, and then transferred into operations. For this, the publication and citability of scientific software have to fulfil scientific criteria by means of defined processes and the use of persistent identifiers, similar to data publications. The SciForge project is addressing these challenges. Based on interviews a blueprint for a scientific software publishing platform and a systematic implementation plan has been designed. In addition, the potential of journals, software repositories and persistent identifiers have been evaluated to improve the publication and dissemination of reusable software solutions. It is important that procedures for publishing software as well as methods and tools for software engineering are reflected in the architecture of the platform, in order to improve the quality of the software and the results of research. In addition, it is necessary to work continuously on improving specific conditions that promote the adoption and sustainable utilization of scientific software publications. Among others, this would include policies for the development and publication of scientific software in the institutions but also policies for establishing the necessary competencies and skills of scientists and IT personnel. To implement the concepts developed in SciForge a combined bottom-up / top-down approach is considered that will be implemented in parallel in different scientific domains, e.g. in earth sciences, climate research and

  15. Topological Active Volumes

    Directory of Open Access Journals (Sweden)

    Barreira N

    2005-01-01

    Full Text Available The topological active volumes (TAVs model is a general model for 3D image segmentation. It is based on deformable models and integrates features of region-based and boundary-based segmentation techniques. Besides segmentation, it can also be used for surface reconstruction and topological analysis of the inside of detected objects. The TAV structure is flexible and allows topological changes in order to improve the adjustment to object's local characteristics, find several objects in the scene, and identify and delimit holes in detected structures. This paper describes the main features of the TAV model and shows its ability to segment volumes in an automated manner.

  16. Aperiodic Volume Optics

    Science.gov (United States)

    Gerke, Tim D.

    Presented in this thesis is an investigation into aperiodic volume optical devices. The three main topics of research and discussion are the aperiodic volume optical devices that we call computer-generated volume holograms (CGVH), defects within periodic 3D photonic crystals, and non-periodic, but ordered 3D quasicrystals. The first of these devices, CGVHs, are designed and investigated numerically and experimentally. We study the performance of multi-layered amplitude computer-generated volume holograms in terms of efficiency and angular/frequency selectivity. Simulation results show that such aperiodic devices can increase diffraction efficiency relative to periodic amplitude volume holograms while maintaining angular and wavelength selectivity. CGVHs are also designed as voxelated volumes using a new projection optimization algorithm. They are investigated using a volumetric diffraction simulation and a standard 3D beam propagation technique as well as experimentally. Both simulation and experiment verify that the structures function according to their design. These represent the first diffractive structures that have the capacity for generating arbitrary transmission and reflection wave fronts and that provide the ability for multiplexing arbitrary functionality given different illumination conditions. Also investigated and discussed in this thesis are 3D photonic crystals and quasicrystals. We demonstrate that these devices can be fabricated using a femtosecond laser direct writing system that is particularly appropriate for fabrication of such arbitrary 3D structures. We also show that these devices can provide 3D partial bandgaps which could become complete bandgaps if fabricated using high index materials or by coating lower index materials with high index metals. Our fabrication method is particularly suited to the fabrication of engineered defects within the periodic or quasi-periodic systems. We demonstrate the potential for fabricating defects within

  17. The volume of a soliton

    Energy Technology Data Exchange (ETDEWEB)

    Adam, C., E-mail: adam@fpaxp1.usc.es [Departamento de Física de Partículas, Universidad de Santiago de Compostela and Instituto Galego de Física de Altas Enerxias (IGFAE), E-15782 Santiago de Compostela (Spain); Haberichter, M. [School of Mathematics, Statistics and Actuarial Science, University of Kent, Canterbury, CT2 7NF (United Kingdom); Wereszczynski, A. [Institute of Physics, Jagiellonian University, Lojasiewicza 11, Kraków (Poland)

    2016-03-10

    There exists, in general, no unique definition of the size (volume, area, etc., depending on dimension) of a soliton. Here we demonstrate that the geometric volume (area etc.) of a soliton is singled out in the sense that it exactly coincides with the thermodynamical or continuum-mechanical volume. In addition, this volume may be defined uniquely for rather arbitrary solitons in arbitrary dimensions.

  18. Hybrid Microfluidic Platform for Multifactorial Analysis Based on Electrical Impedance, Refractometry, Optical Absorption and Fluorescence

    Directory of Open Access Journals (Sweden)

    Fábio M. Pereira

    2016-10-01

    Full Text Available This paper describes the development of a novel microfluidic platform for multifactorial analysis integrating four label-free detection methods: electrical impedance, refractometry, optical absorption and fluorescence. We present the rationale for the design and the details of the microfabrication of this multifactorial hybrid microfluidic chip. The structure of the platform consists of a three-dimensionally patterned polydimethylsiloxane top part attached to a bottom SU-8 epoxy-based negative photoresist part, where microelectrodes and optical fibers are incorporated to enable impedance and optical analysis. As a proof of concept, the chip functions have been tested and explored, enabling a diversity of applications: (i impedance-based identification of the size of micro beads, as well as counting and distinguishing of erythrocytes by their volume or membrane properties; (ii simultaneous determination of the refractive index and optical absorption properties of solutions; and (iii fluorescence-based bead counting.

  19. Nanoparticle functionalised small-core suspended-core fibre – a novel platform for efficient sensing

    Science.gov (United States)

    Doherty, Brenda; Csáki, Andrea; Thiele, Matthias; Zeisberger, Matthias; Schwuchow, Anka; Kobelke, Jens; Fritzsche, Wolfgang; Schmidt, Markus A.

    2017-01-01

    Detecting small quantities of specific target molecules is of major importance within bioanalytics for efficient disease diagnostics. One promising sensing approach relies on combining plasmonically-active waveguides with microfluidics yielding an easy-to-use sensing platform. Here we introduce suspended-core fibres containing immobilised plasmonic nanoparticles surrounding the guiding core as a concept for an entirely integrated optofluidic platform for efficient refractive index sensing. Due to the extremely small optical core and the large adjacent microfluidic channels, over two orders of magnitude of nanoparticle coverage densities have been accessed with millimetre-long sample lengths showing refractive index sensitivities of 170 nm/RIU for aqueous analytes where the fibre interior is functionalised by gold nanospheres. Our concept represents a fully integrated optofluidic sensing system demanding small sample volumes and allowing for real-time analyte monitoring, both of which are highly relevant within invasive bioanalytics, particularly within molecular disease diagnostics and environmental science. PMID:28270985

  20. Managing the computational chemistry big data problem: the ioChem-BD platform.

    Science.gov (United States)

    Álvarez-Moreno, M; de Graaf, C; López, N; Maseras, F; Poblet, J M; Bo, C

    2015-01-26

    We present the ioChem-BD platform ( www.iochem-bd.org ) as a multiheaded tool aimed to manage large volumes of quantum chemistry results from a diverse group of already common simulation packages. The platform has an extensible structure. The key modules managing the main tasks are to (i) upload of output files from common computational chemistry packages, (ii) extract meaningful data from the results, and (iii) generate output summaries in user-friendly formats. A heavy use of the Chemical Mark-up Language (CML) is made in the intermediate files used by ioChem-BD. From them and using XSL techniques, we manipulate and transform such chemical data sets to fulfill researchers' needs in the form of HTML5 reports, supporting information, and other research media.

  1. A platform independent communication library for distributed computing

    NARCIS (Netherlands)

    Groen, D.; Rieder, S.; Grosso, P.; de Laat, C.; Portegies Zwart, S.

    2010-01-01

    We present MPWide, a platform independent communication library for performing message passing between supercomputers. Our library couples several local MPI applications through a long distance network using, for example, optical links. The implementation is deliberately kept light-weight, platform

  2. Towards A Research Agenda on Digital Platform Disruption

    DEFF Research Database (Denmark)

    Kazan, Erol; Tan, Chee-Wee; Lim, Eric T. K.

    Digital platforms are disruptive IT artifacts, because they facilitate the quick release of innovative platform derivatives from third parties. This study endeavors to unravel the disruptive potential, caused by distinct designs and configurations of digital platforms on market environments. We...... postulate that the disruptive potential of digital platforms is determined by the degree of alignment among the business, technology and platform profiles. Furthermore, we argue that the design and configuration of the aforementioned three elements dictates the extent to which open innovation is permitted....... To shed light on the disruptive potential of digital platforms, we opted for digital payment platforms as our unit of analysis. Through interviews with experts and payment providers, we seek to gain an in-depth appreciation of how contemporary digital payment platforms are designed and configured...

  3. Towards A Research Agenda on Digital Platform Disruption

    DEFF Research Database (Denmark)

    Kazan, Erol; Tan, Chee-Wee; Lim, Eric T. K.

    Digital platforms are disruptive IT artifacts, because they facilitate the quick release of innovative platform derivatives from third parties. This study endeavors to unravel the disruptive potential, caused by distinct designs and configurations of digital platforms on market environments. We...... postulate that the disruptive potential of digital platforms is determined by the degree of alignment among the business, technology and platform profiles. Furthermore, we argue that the design and configuration of the aforementioned three elements dictates the extent to which open innovation is permitted....... To shed light on the disruptive potential of digital platforms, we opted for digital payment platforms as our unit of analysis. Through interviews with experts and payment providers, we seek to gain an in-depth appreciation of how contemporary digital payment platforms are designed and configured...

  4. Automated microfluidic screening assay platform based on DropLab.

    Science.gov (United States)

    Du, Wen-Bin; Sun, Meng; Gu, Shu-Qing; Zhu, Ying; Fang, Qun

    2010-12-01

    This paper describes DropLab, an automated microfluidic platform for programming droplet-based reactions and screening in the nanoliter range. DropLab can meter liquids with picoliter-scale precision, mix multiple components sequentially to assemble composite droplets, and perform screening reactions and assays in linear or two-dimensional droplet array with extremely low sample and reagent consumptions. A novel droplet generation approach based on the droplet assembling strategy was developed to produce multicomponent droplets in the nanoliter to picoliter range with high controllability on the size and composition of each droplet. The DropLab system was built using a short capillary with a tapered tip, a syringe pump with picoliter precision, and an automated liquid presenting system. The tapered capillary was used for precise liquid metering and mixing, droplet assembling, and droplet array storage. Two different liquid presenting systems were developed based on the slotted-vial array design and multiwell plate design to automatically present various samples, reagents, and oil to the capillary. Using the tapered-tip capillary and the picoliter-scale precision syringe pump, the minimum unit of the droplet volume in the present system reached ~20 pL. Without the need of complex microchannel networks, various droplets with different size (20 pL-25 nL), composition, and sequence were automatically assembled, aiming to multiple screening targets by simply adjusting the types, volumes, and mixing ratios of aspirated liquids on demand. The utility of DropLab was demonstrated in enzyme inhibition assays, protein crystallization screening, and identification of trace reducible carbohydrates.

  5. Platform Based Design for Automotive Sensor Conditioning

    CERN Document Server

    Fanucci, L; Iozzi, F; Marino, C; Rocchi, A

    2011-01-01

    In this paper a general architecture suitable to interface several kinds of sensors for automotive applications is presented. A platform based design approach is pursued to improve system performance while minimizing time-to-market.. The platform is composed by an analog front-end and a digital section. The latter is based on a microcontroller core (8051 IP by Oregano) plus a set of dedicated hardware dedicated to the complex signal processing required for sensor conditioning. The microcontroller handles also the communication with external devices (as a PC) for data output and fast prototyping. A case study is presented concerning the conditioning of a Gyro yaw rate sensor for automotive applications. Measured performance results outperform current state-of-the-art commercial devices.

  6. Molecular cell death platforms and assemblies.

    Science.gov (United States)

    Mace, Peter D; Riedl, Stefan J

    2010-12-01

    Multi-cellular animals have evolved a variety of mechanisms to respond to diverse apoptotic stimuli. In general these proceed through activation of apical caspases and culminate in executioner caspase activation and cell death. Because of the breadth of possible initiators, various molecular platforms are used to trigger different apical caspases. Although some common protein domains are used to assemble the apoptosome, the PIDDosome and death receptor complexes, an array of checks-and-balances are employed to ensure appropriate activation. Notwithstanding, these pathways share the underlying principle of proximity-dependent activation and post-translational modification. Here we will describe our current structural understanding of assembly and regulation of these signaling platforms.

  7. Virtual interconnection platform initiative scoping study

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Yong [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Kou, Gefei [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Pan, Zuohong [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Liu, Yilu [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); King Jr., Thomas J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2016-01-01

    Due to security and liability concerns, the research community has limited access to realistic large-scale power grid models to test and validate new operation and control methodologies. It is also difficult for industry to evaluate the relative value of competing new tools without a common platform for comparison. This report proposes to develop a large-scale virtual power grid model that retains basic features and represents future trends of major U.S. electric interconnections. This model will include realistic power flow and dynamics information as well as a relevant geospatial distribution of assets. This model will be made widely available to the research community for various power system stability and control studies and can be used as a common platform for comparing the efficacies of various new technologies.

  8. Security issues in e-learning platforms

    Directory of Open Access Journals (Sweden)

    Defta (Ciobanu Costinela – Luminita

    2011-12-01

    Full Text Available Security is an important issue in the actual educational context where e-learning increases in popularity and increasingly more people are taking online courses. The e-learning platforms are today production systems that need to be secured. To achieve a good level of security, there are many important elements that must be taken into account: authentication, access control, data integrity, content protection, etc. Information security can be obtained using methods such as cryptography and network protocols. In this paper we will highlight some key security issues that must be taken into consideration in developing and using an e-learning platform. We will also examine some security aspects of one of the most popular open-source e-learning systems: Moodle.

  9. A Simulation Platform for Quantifying Survival Bias

    DEFF Research Database (Denmark)

    Mayeda, Elizabeth Rose; Tchetgen Tchetgen, Eric J; Power, Melinda C

    2016-01-01

    Bias due to selective mortality is a potential concern in many studies and is especially relevant in cognitive aging research because cognitive impairment strongly predicts subsequent mortality. Biased estimation of the effect of an exposure on rate of cognitive decline can occur when mortality i......-mortality situations. This simulation platform provides a flexible tool for evaluating biases in studies with high mortality, as is common in cognitive aging research.......Bias due to selective mortality is a potential concern in many studies and is especially relevant in cognitive aging research because cognitive impairment strongly predicts subsequent mortality. Biased estimation of the effect of an exposure on rate of cognitive decline can occur when mortality...... platform with which to quantify the expected bias in longitudinal studies of determinants of cognitive decline. We evaluated potential survival bias in naive analyses under several selective survival scenarios, assuming that exposure had no effect on cognitive decline for anyone in the population. Compared...

  10. Perfect discipline platform and Promote interactive development

    Directory of Open Access Journals (Sweden)

    Xiang-ming ZENG

    2014-11-01

    Full Text Available Through the questionnaire survey of Marxism’s course construction and Ideological and Political Theory Course in 45 universities, the paper tries to discuss how to enhance the effectiveness of ideological and political theory course by platform of Marxism’s course construction. Research shows that it can enhance the effectiveness of Ideological and Political Theory Course as long as we make full use of platform construction of Marxism’s course, fully display the Marxism’s spirit with the times and the latest achievements in Ideological and political theory course, and Strengthen academic ideological and Political Theory Education. We believe that it can better cultivate socialist builders to achieve the Chinese dream by playing the educational function of Ideological and Political Theory Course.

  11. Hurricane damaged fixed platforms and wellhead structures

    Energy Technology Data Exchange (ETDEWEB)

    Shuttleworth, E.P.; Frieze, P.A.

    1998-03-01

    The objective of this study was to review data on damages to offshore platforms with a view to determining their suitability for further exploitation and analysis through a preliminary assessment of trends in the data when viewed from a risk standpoint. To realise this objective, a database on hurricane and other storm related damages was generated and past design practice, particularly concerning environmental load levels, was established. Information was gathered on extreme wave heights, damages, platform details, pushover analyses and structural frame load tests. The information was obtained through: a literature survey of journals, conference proceedings, design codes and guidelines; approaches to organisations in the offshore industry with significant experience of hurricanes, storm-damaged structures and pushover analyses; and interrogation of three major databases on offshore storm and other damages - PMB, MMS and WOAD. (author)

  12. The socializing role of expatriate online platforms

    DEFF Research Database (Denmark)

    Emontspool, Julie

    2015-01-01

    This chapter discusses the role of Information and Communication Technologies (ICTs) in expatriates’ secondary socialization into new consumption environments. On the basis of the qualitative study of a question and answer platform directed at expatriates in Brussels, this chapter differentiates ...... into the consequences of those online interactions for nationalism, where digital tools may in fact reduce expatriates’ cosmopolitanism. Secondly, the study shows collaborative knowledge construction on those platforms creates new forms of market adaptation....... between market orientation and socialization practices online. It shows how processes of market simplification, market guidance and market manipulation co-exist both in expatriates’ orientation and socialization in the new consumption context. The findings of this study firstly provide insights...

  13. Towards gaze-controlled platform games

    DEFF Research Database (Denmark)

    Muñoz, Jorge; Yannakakis, Georgios N.; Mulvey, Fiona

    2011-01-01

    This paper introduces the concept of using gaze as a sole modality for fully controlling player characters of fast-paced action computer games. A user experiment is devised to collect gaze and gameplay data from subjects playing a version of the popular Super Mario Bros platform game. The initial...... analysis shows that there is a rather limited grid around Mario where the efficient player focuses her attention the most while playing the game. The useful grid as we name it, projects the amount of meaningful visual information a designer should use towards creating successful player character...... controllers with the use of artificial intelligence for a platform game like Super Mario. Information about the eyes' position on the screen and the state of the game are utilized as inputs of an artificial neural network, which is trained to approximate which keyboard action is to be performed at each game...

  14. Dynamic Analysis of Offshore Spar Platforms

    Directory of Open Access Journals (Sweden)

    A. K. Jain

    2003-04-01

    Full Text Available Offshore spar platform is a compliant offshore floating structure used for deep water applications for drilling, production, processing, storage and offloading of ocean deposits. The offshore spar platform is modelled as a rigid body with six degrees-of-freedom (DOFs, connected to the sea bed by multicomponent catenary cables which consist of a mooring line, a clump weight, and an anchor line attached to the fairlcads. The response-dependent stiffness matrix consists of three parts: (i the restoring hydrostatic force, and the stiffness due to cables. (ii nonlinear horizontal springs, and (iii nonlinear vertical springs. A unidirectional regular wave model is used for computing the incident wave kinematics by Airy's wave theory and  hydrodynamic force by Morison's equation. The response analysis is performed in timc domain using the iterative incremental Newmark's method. Numerical studies have been conducted for sea state conditions with and without coupling of DOFs.

  15. Chein loops as potential platforms for cryptosystems

    Science.gov (United States)

    Chee, Wing Loon

    2013-04-01

    The Diffie-Hellman key exchange protocol is one of the well-known examples of public key cryptography which is based on the discrete logarithm problem (DLP): given integers g, h and n, find an integer a such that ga≡h(modn). In 2000, Ko, Lee et al. generalised the Diffie-Hellman protocol by using a class of algebraic structures called braid groups as platforms. Its security lies on the conjugacy search problem (CSP): given elements g and h in a group, find an element a in the group such that a-1ga = h. In this paper, we propose another key exchange protocol by using Chein loops—a subclass of Moufang loops. We shall discuss their potential as platforms for cryptosystems and their connection with the Ko-Lee et al. protocol.

  16. Porting salinas to the windows platform.

    Energy Technology Data Exchange (ETDEWEB)

    Reese, Garth M.; Wilson, Christopher Riley

    2006-06-01

    The ASC program has enabled significant development of high end engineering applications on massively parallel machines. There is a great benefit in providing these applications on the desktop of the analysts and designers, at least insofar as the small models may be run on these platforms, thus providing a tool set that spans the application needs. This effort documents the work of porting Salinas to the WINDOWS{trademark} platform. Selection of the tools required to compile, link, test and run Salinas in this environment is discussed. Significant problems encountered along the way are listed along with an estimation of the overall cost of the port. This report may serve as a baseline for streamlining further porting activities with other ASC codes.

  17. Modeling and simulation of luminescence detection platforms.

    Science.gov (United States)

    Salama, Khaled; Eltoukhy, Helmy; Hassibi, Arjang; El-Gamal, Abbas

    2004-06-15

    Motivated by the design of an integrated CMOS-based detection platform, a simulation model for CCD and CMOS imager-based luminescence detection systems is developed. The model comprises four parts. The first portion models the process of photon flux generation from luminescence probes using ATP-based and luciferase label-based assay kinetics. An optics simulator is then used to compute the incident photon flux on the imaging plane for a given photon flux and system geometry. Subsequently, the output image is computed using a detailed imaging sensor model that accounts for photodetector spectral response, dark current, conversion gain, and various noise sources. Finally, signal processing algorithms are applied to the image to enhance detection reliability and hence increase the overall system throughput. To validate the model, simulation results are compared to experimental results obtained from a CCD-based system that was built to emulate the integrated CMOS-based platform.

  18. Novel Biochip Platform for Nucleic Acid Analysis

    Directory of Open Access Journals (Sweden)

    Juan J. Diaz-Mochon

    2012-06-01

    Full Text Available This manuscript describes the use of a novel biochip platform for the rapid analysis/identification of nucleic acids, including DNA and microRNAs, with very high specificity. This approach combines a unique dynamic chemistry approach for nucleic acid testing and analysis developed by DestiNA Genomics with the STMicroelectronics In-Check platform, which comprises two microfluidic optimized and independent PCR reaction chambers, and a sequential microarray area for nucleic acid capture and identification by fluorescence. With its compact bench-top “footprint” requiring only a single technician to operate, the biochip system promises to transform and expand routine clinical diagnostic testing and screening for genetic diseases, cancers, drug toxicology and heart disease, as well as employment in the emerging companion diagnostics market.

  19. Nordic Baltic innovation platform for Creative Industries

    DEFF Research Database (Denmark)

    Dickson, Thomas; Järvinen, Juha; Koski, Emilia

    2006-01-01

    The purpose of this project report is to explore the potential the current status of Creative Industries (CI) and design innovation programmes provide in the Nordic-Baltic area. Moreover, this report reviews the possibilities of building an innovation platform in the Nordic-Baltic region....... To illustrate the prevailing situation, this report reviews and analyses Creative Industries and design innovation systems and actors, design promotion and its actors in each country, activities and measures – around design – in each country (main research programmes, innovation transfer systems) and finally......, results achieved in each country (new knowledge created, new forms of activities etc.), in the Nordic and Baltic region, respectively. This report concludes with discussion and an idea of how the innovation platform could be built....

  20. Development of a PDXP platform on NIF

    Science.gov (United States)

    Whitley, Heather; Schneider, Marilyn; Garbett, Warren; Pino, Jesse; Shepherd, Ronnie; Brown, Colin; Castor, John; Scott, Howard; Ellison, C. Leland; Benedict, Lorin; Sio, Hong; Lahmann, Brandon; Petrasso, Richard; Graziani, Frank

    2016-10-01

    Over the past several years, we have conducted theoretical investigations of electron-ion coupling and electronic transport in plasmas. In the regime of weakly coupled plasmas, we have identified models that we believe describe the physics well, but experimental measurements are still needed to validate the models. We are developing spectroscopic experiments to study electron-ion equilibration and electron heat transport using a polar direct drive exploding pusher (PDXP) platform at the National Ignition Facility (NIF). Initial measurements are focused on characterizing the laser-target coupling, symmetry of the PDXP implosion, and overall neutron and x-ray signals. We present images from the first set of shots and make comparisons with simulations from ARES and discuss next steps in the platform development. Prepared by LLNL under Contract DE-AC52-07NA27344. LLNL-ABS-697489.

  1. Speeding up Derivative Configuration from Product Platforms

    Directory of Open Access Journals (Sweden)

    Ruben Heradio

    2014-06-01

    Full Text Available To compete in the global marketplace, manufacturers try to differentiate their products by focusing on individual customer needs. Fulfilling this goal requires that companies shift from mass production to mass customization. Under this approach, a generic architecture, named product platform, is designed to support the derivation of customized products through a configuration process that determines which components the product comprises. When a customer configures a derivative, typically not every combination of available components is valid. To guarantee that all dependencies and incompatibilities among the derivative constituent components are satisfied, automated configurators are used. Flexible product platforms provide a big number of interrelated components, and so, the configuration of all, but trivial, derivatives involves considerable effort to select which components the derivative should include. Our approach alleviates that effort by speeding up the derivative configuration using a heuristic based on the information theory concept of entropy.

  2. Supporting Building Portfolio Investment and Policy Decision Making through an Integrated Building Utility Data Platform

    Energy Technology Data Exchange (ETDEWEB)

    Aziz, Azizan [Carnegie Mellon Univ., Pittsburgh, PA (United States); Lasternas, Bertrand [Carnegie Mellon Univ., Pittsburgh, PA (United States); Alschuler, Elena [US DOE; View Inc; Loftness, Vivian [Carnegie Mellon Univ., Pittsburgh, PA (United States); Wang, Haopeng [Carnegie Mellon Univ., Pittsburgh, PA (United States); Mo, Yunjeong [Carnegie Mellon Univ., Pittsburgh, PA (United States); Wang, Ting [Carnegie Mellon Univ., Pittsburgh, PA (United States); Zhang, Chenlu [Carnegie Mellon Univ., Pittsburgh, PA (United States); Sharma, Shilpi [Carnegie Mellon; Stevens, Ivana [Carnegie Mellon Univ., Pittsburgh, PA (United States)

    2016-03-18

    The American Recovery and Reinvestment Act stimulus funding of 2009 for smart grid projects resulted in the tripling of smart meters deployment. In 2012, the Green Button initiative provided utility customers with access to their real-time1 energy usage. The availability of finely granular data provides an enormous potential for energy data analytics and energy benchmarking. The sheer volume of time-series utility data from a large number of buildings also poses challenges in data collection, quality control, and database management for rigorous and meaningful analyses. In this paper, we will describe a building portfolio-level data analytics tool for operational optimization, business investment and policy assessment using 15-minute to monthly intervals utility data. The analytics tool is developed on top of the U.S. Department of Energy’s Standard Energy Efficiency Data (SEED) platform, an open source software application that manages energy performance data of large groups of buildings. To support the significantly large volume of granular interval data, we integrated a parallel time-series database to the existing relational database. The time-series database improves on the current utility data input, focusing on real-time data collection, storage, analytics and data quality control. The fully integrated data platform supports APIs for utility apps development by third party software developers. These apps will provide actionable intelligence for building owners and facilities managers. Unlike a commercial system, this platform is an open source platform funded by the U.S. Government, accessible to the public, researchers and other developers, to support initiatives in reducing building energy consumption.

  3. 28. annual offshore technology conference: Proceedings. Volume 3: Construction and installation

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    The 32 papers in this volume cover the following topics: Gulf of Mexico developments -- Popeye and SeaStar; Materials, utilization and fabrication; Mooring and station keeping; Offshore pipelines; and Platform installation. Most papers have been processed separately for inclusion on the data base.

  4. The Entrepreneurial Domains of American Higher Education. ASHE Higher Education Report, Volume 34, Number 5

    Science.gov (United States)

    Mars, Matthew M.; Metcalf, Amy Scott

    2009-01-01

    This volume draws on a diverse set of literatures to represent the various ways in which entrepreneurship is understood in and applied to higher education. It provides a platform for debate for those considering applications of entrepreneurial principles to academic research and practices. Using academic entrepreneurship in the United States as…

  5. En Billig GPS Data Analyse Platform

    DEFF Research Database (Denmark)

    Andersen, Ove; Christiansen, Nick; Larsen, Niels T.

    2011-01-01

    Denne artikel præsenterer en komplet software platform til analyse af GPS data. Platformen er bygget udelukkende vha. open-source komponenter. De enkelte komponenter i platformen beskrives i detaljer. Fordele og ulemper ved at bruge open-source diskuteres herunder hvilke IT politiske tiltage, der...... organisationer med et digitalt vejkort og GPS data begynde at lave trafikanalyser på disse data. Det er et krav, at der er passende IT kompetencer tilstede i organisationen....

  6. The onboard control system of "Navigator" platform

    Science.gov (United States)

    Syrov, A. S.; Smirnov, V. V.; Sokolov, V. N.; Iodko, G. S.; Mischikhin, V. V.; Kosobokov, V. N.; Shatskii, M. A.; Dobrynin, D. A.

    2016-12-01

    A brief description of the design concept, structure and performance of the onboard control system (AOCS) of the "Navigator" satellite platform, on the basis of which the spacecraft "Electro-L' and "Spektr-R" are designed, is presented. The test-flight results of the AOCS attitude accuracy are given. Approaches to the further development of the onboard control equipment for advanced spacecraft are determined and presented.

  7. Self-Healing Distributed Scheduling Platform

    OpenAIRE

    Frincu M.E.; Villegas N.M.; Petcu D.; Muller H.A.; Rouvoy R.

    2011-01-01

    International audience; Distributed systems require effective mechanisms to manage the reliable provisioning of computational resources from different and distributed providers. Moreover, the dynamic environment that affects the behaviour of such systems and the complexity of these dynamics demand autonomous capabilities to ensure the behaviour of distributed scheduling platforms and to achieve business and user objectives. In this paper we propose a self-adaptive distributed scheduling platf...

  8. En Billig GPS Data Analyse Platform

    DEFF Research Database (Denmark)

    Andersen, Ove; Christiansen, Nick; Larsen, Niels T.;

    2011-01-01

    Denne artikel præsenterer en komplet software platform til analyse af GPS data. Platformen er bygget udelukkende vha. open-source komponenter. De enkelte komponenter i platformen beskrives i detaljer. Fordele og ulemper ved at bruge open-source diskuteres herunder hvilke IT politiske tiltage, der...... organisationer med et digitalt vejkort og GPS data begynde at lave trafikanalyser på disse data. Det er et krav, at der er passende IT kompetencer tilstede i organisationen....

  9. Verification of Slam Methods on Ros Platform

    OpenAIRE

    Radovan Sivý; Daniela Perudková

    2016-01-01

    The paper deals with the problem of experimental vehicle concept for 3D SLAM method based on data from Kinect device. One part of the paper describes the design, implementation and description of the physical model of the experimental vehicle. The second describes an odometry representation with a mathematical model of the Ackerman steering as well. Next describes the ROS platform, which was determined to solve complex robotic tasks. Last part of the paper contains to the evaluation of the re...

  10. Nye pladser og platforme i byen

    DEFF Research Database (Denmark)

    Andersson, Lasse

    2010-01-01

    projekter som Platform4 i Aalborg og NDSM værftet i Amsterdam samt Skateparken i Malmö stilles skarpt på det nye landskab af kreative iværksættere og kulturbrugere som har potentiale som fremtidige ’kunder’ i butikken hos de danske kulturhuse. Det kræver dog, at kulturhusene og deres medarbejdere forstår de...

  11. Progress at Standard Space Platforms Corporation

    Science.gov (United States)

    Perkins, Frederick W.

    1992-08-01

    An account is given of a simple program structure with low costs and short schedules for the space R&D community operating outside mission-oriented, government-funded programs. In addition to furnishing launch services into orbit, the program structure furnishes engineering services through its ground station, control room, and 3-year duration 'MMSB' platform. Flights may begin as little as a year after contract signature.

  12. Large Platform Autonomy in Urban Environments

    Science.gov (United States)

    2012-08-01

    low cost ESO Stereo Video module and a commercially available automotive Millimeter Wave RADAR (MMWR) module. These sensors are shown in Figure 2...SYSTEMS (RS) MINI-SYMPOSIUM AUGUST 14-16, MICHIGAN LARGE PLATFORM AUTONOMY IN URBAN ENVIRONMENTS Chip DiBerardino Edward Mottern Tracy K...NUMBER 6. AUTHOR(S) Dariusz Mikulski; N. kott; Chip DiBerardino; Edward Mottern; Tracy Van Lierop 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT

  13. Design for volume reduction

    NARCIS (Netherlands)

    Wever, R.; Boks, C.; Stevels, A.

    2007-01-01

    Traditionally packaging design-for-sustainability (DfS) strongly focuses on resource conservation and material recycling. The type and amount of materials used has been the driver in design. For consumer electronics (CE) products this weight-based approach is too limited; a volume-based approach is

  14. Introduction to the Volume.

    Science.gov (United States)

    Emihovich, Catherine; Schroder, Barbara; Panofsky, Carolyn P.

    1999-01-01

    Introduces a volume that examines the issue of critical thinking and whether or not it is culturally specific, discussing recent research on the subject. The papers focus on critical thinking and culture, historical consciousness and critical thinking, critical thinking as cultural-historical practice, culture and the development of critical…

  15. Research on informational operation application of tactical loitering platform

    Science.gov (United States)

    Wang, Huanhuan; Zhang, Jun; Li, Guoshu; Song, Jinxing; Zhang, Yunhao

    2016-11-01

    The tactical loitering platform, as a multifunctional precision guided weapon, is an important part of constitution of information warfare. Using the combined propulsion system, the flying mode of platform includes supersonic cruise and subsonic loiter. With different loads, the platform is information warfare equipments with functions of region spying, communication control, electronic jamming, target tracking, accurate attack and damage assessment. Also the ability of platform can be enforced by using data link system in the informational operation.

  16. Platform for Modeling and Simulation of Photovoltaic Generation Systems

    Directory of Open Access Journals (Sweden)

    Anny A. Arroyave-Berrio

    2013-11-01

    Full Text Available A platform for modeling and simulation using Matlab is presented. The platform has four models of photovoltaic panels. It identifies the parameters of each one, for a given solar panel, based on experimental data of voltage, current and environmental conditions. Also the platform generates four blocks, for using in Matlab-Simulink and Psim simulation tools. The experimental validation of the platform was made using the PV panels of the Metropolitan Technological Institute (ITM Lab.

  17. SERS diagnostic platforms, methods and systems microarrays, biosensors and biochips

    Energy Technology Data Exchange (ETDEWEB)

    Vo-Dinh, Tuan (Knoxville, TN)

    2007-09-11

    A Raman integrated sensor system for the detection of targets including biotargets includes at least one sampling platform, at least one receptor probe disposed on the sampling platform, and an integrated circuit detector system communicably connected to the receptor. The sampling platform is preferably a Raman active surface-enhanced scattering (SERS) platform, wherein the Raman sensor is a SERS sensor. The receptors can include at least one protein receptor and at least one nucleic acid receptor.

  18. SERS diagnostic platforms, methods and systems microarrays, biosensors and biochips

    Science.gov (United States)

    Vo-Dinh, Tuan

    2007-09-11

    A Raman integrated sensor system for the detection of targets including biotargets includes at least one sampling platform, at least one receptor probe disposed on the sampling platform, and an integrated circuit detector system communicably connected to the receptor. The sampling platform is preferably a Raman active surface-enhanced scattering (SERS) platform, wherein the Raman sensor is a SERS sensor. The receptors can include at least one protein receptor and at least one nucleic acid receptor.

  19. AN ANALYSIS ON CHOOSING A PROPER ECOMMERCE PLATFORM

    OpenAIRE

    Radu Lixandroiu; Catalin Maican

    2015-01-01

    Choosing an electronic trading platform is a very important decision when opening an online store. A suitable platform must be able to meet many of the requirements as to not confuse the user. It should provide an online business operation providing tools for managing back-office of technically. There are dozens maybe hundreds of electronic ecommerce platforms available to create an online store, so the decision to choose a platform is difficult. In this article, we tried to compare 19 of the...

  20. Platform2008年用户大全

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    2008年10月14,Platform 2008年用户大会在京举行.Platform 公司此间宣布将向市场推出多款析产品,包括LSF.X系列、系统管理软件Platform (Scali) manager、并行运算支持库Platform(Scali) MPI、网络技术软件EGO以及云技术软件VMO等.

  1. Source ATO - Large Platform Autonomy in Urban Environments

    Science.gov (United States)

    2012-08-06

    Platform Demonstrator (APD) GPS/INS Navigation System Automotive Radar Platform and Autonomy System - T2 6 August 2012 7 Navigation Unit RR N...SOURCE ATO - Large Platform Autonomy in Urban Environments N. Joseph Kott (TARDEC) Dariusz Mikulski (TARDEC) Chip DiBerardino (GDRS) Edward...120-F GPS/IRU Scanning LADAR: Very Low Cost LADAR (VLCL) Automotive MMWR Stereo Video: ESO Stereo Module T2 UGV Platform TARDEC developed

  2. Product Information Platform Based on STEP

    Institute of Scientific and Technical Information of China (English)

    WANG Taiyong; ZHANG Zhiwei

    2009-01-01

    The intemational standard ISO 10303.called STEP.has been used to deal with problems in the ex change of product models and the associated data between difierent computer-aided systems.A platform based on STEP for managing product information is presented.This platform includes three components:a product geometry information model,a product feature model and a product visualization model.An information extracting pattern,in which information is extracted from low level elements to high level ones,is adopted in establishing the product geometry information model.Relative elements lists are created based on the extracted product information.With the traversing of these lists,feature extraction methods are proposed,which take advantage of boundary information in product model and avoid the determination of concavity and convexity of curves.Information correlating to features iS stored in a structure named as feature block and the product visualization model iS founded from it.The feature block is used in the platform for information communication and synchronous update among the three components.

  3. Hybrid Photonic Integration on a Polymer Platform

    Directory of Open Access Journals (Sweden)

    Ziyang Zhang

    2015-09-01

    Full Text Available To fulfill the functionality demands from the fast developing optical networks, a hybrid integration approach allows for combining the advantages of various material platforms. We have established a polymer-based hybrid integration platform (polyboard, which provides flexible optical input/ouptut interfaces (I/Os that allow robust coupling of indium phosphide (InP-based active components, passive insertion of thin-film-based optical elements, and on-chip attachment of optical fibers. This work reviews the recent progress of our polyboard platform. On the fundamental level, multi-core waveguides and polymer/silicon nitride heterogeneous waveguides have been fabricated, broadening device design possibilities and enabling 3D photonic integration. Furthermore, 40-channel optical line terminals and compact, bi-directional optical network units have been developed as highly functional, low-cost devices for the wavelength division multiplexed passive optical network. On a larger scale, thermo-optic elements, thin-film elements and an InP gain chip have been integrated on the polyboard to realize a colorless, dual-polarization optical 90° hybrid as the frontend of a coherent receiver. For high-end applications, a wavelength tunable 100Gbaud transmitter module has been demonstrated, manifesting the joint contribution from the polyboard technology, high speed polymer electro-optic modulator, InP driver electronics and ceramic electronic interconnects.

  4. PLATFORM OF TRANSCRIPTION THE OLD ARABIC MANUSCRIPTS

    Directory of Open Access Journals (Sweden)

    Noureddine EL MAKHFI

    2011-06-01

    Full Text Available The old manuscripts kept in libraries are a part of the richest cultural heritage and legacy of civilizations. Digitalization is a solution for the preservation of this cultural and historical heritage, which is very difficult to handle for users. On the other hand, restriction of access to national heritage manuscript is related to the concern to preserve the manuscripts physically manipulated which contribute to their accelerated degradation, takinginto consideration these limitations on access while ensuring preservation of original manuscripts, the solution widely adopted is based partly on the digitization of this heritage manuscript, and partly on the development of management platforms and diffusion of this wealth of knowledge digitized. We propose in this paper a platform of transcription and establishment by annotating images of manuscripts, these annotations are respecting a XML model. The search in the images of a handwritten document, the rich functionality, intuitive user interface, portability, extensibility and the powerful of the XML technology all make the platform of transcription and establishment an ideal explorer for a specialists and readers of ancient Arabic manuscripts.

  5. Instrument platforms for thin-layer chromatography.

    Science.gov (United States)

    Bernard-Savary, Pierre; Poole, Colin F

    2015-11-20

    High performance column and thin-layer chromatography are both instrumental techniques but differ in that column chromatography requires a fully integrated instrument platform with high pressure capability while for thin-layer chromatography separate devices are used for each unit operation, usually at or close to atmospheric pressure, and afford higher flexibility supporting on-line or off-line operation. The unit operations of thin-layer chromatography are defined as sample application, development and evaluation with derivatization as an optional step. The diversity of equipment for each operation contributes to the flexibility of analysis by thin-layer chromatography and supports manual, semi-automated or full-automation of the separation process. Instrument platforms are more than a convenience as they affect performance, repeatability, sample detectability, and time management. The current trend in thin-layer chromatography is to make the unit operations independent of the user so that analysts can perform other tasks while each step is performed. In addition, in thin-layer chromatography it is general practice to separate several samples simultaneously, and instrument platforms are required to accommodate this feature. In this article, we review contemporary instrumentation employed in thin-layer chromatography for sample application, development, derivatization, photodocumentation, densitometric evaluation, and hyphenation with spectroscopic detectors with an emphasis on the variety and performance of commercially available systems. Some suggestions for best practices and avoidance of common mistakes are included. Copyright © 2015 Elsevier B.V. All rights reserved.

  6. Platform Architecture for Decentralized Positioning Systems

    Directory of Open Access Journals (Sweden)

    Zakaria Kasmi

    2017-04-01

    Full Text Available A platform architecture for positioning systems is essential for the realization of a flexible localization system, which interacts with other systems and supports various positioning technologies and algorithms. The decentralized processing of a position enables pushing the application-level knowledge into a mobile station and avoids the communication with a central unit such as a server or a base station. In addition, the calculation of the position on low-cost and resource-constrained devices presents a challenge due to the limited computing, storage capacity, as well as power supply. Therefore, we propose a platform architecture that enables the design of a system with the reusability of the components, extensibility (e.g., with other positioning technologies and interoperability. Furthermore, the position is computed on a low-cost device such as a microcontroller, which simultaneously performs additional tasks such as data collecting or preprocessing based on an operating system. The platform architecture is designed, implemented and evaluated on the basis of two positioning systems: a field strength system and a time of arrival-based positioning system.

  7. Architectural view model for an integration platform

    Directory of Open Access Journals (Sweden)

    Tomasz Górski

    2012-03-01

    Full Text Available The most common architectural view model is "4+1" by Philipe Kruchten. This model presents the views required for a full description of computer system architecture. By contrast, this model seems to be insufficient to describe architecture of integration platform. Definitely lacks the view of integrated business processes. In the serviceoriented approach, one of the basic elements is a contract. It should also be included in the description of the architecture. Moreover, very important are integration mechanisms and mediation flows that should be presented in the description of architecture. Hence the need for integrated services view, and manner of their integration on the enterprise service bus. Use case view should also be extended by stereotypes required for presenting functionality exposed for other computer systems. It is therefore proposed architectural view model “1+5” for an integration platform. This model has following architectural views: Integrated processes, Use Cases, Logical, Integrated Services, Contracts, Deployment. Furthermore, in article was presented new UML profile "UML Profile for Integration Flows". In the profile were placed stereotypes corresponding to integration patterns and mediation mechanisms. It is important, that UML activity diagram was extended and its special form was obtained to model mediation flows on integration platform. Thus was proposed a new UML diagram: mediation flows diagram.

  8. A novel platform device for rodent echocardiography.

    Science.gov (United States)

    Kutschka, Ingo; Sheikh, Ahmad Y; Sista, Ramachandra; Hendry, Stephen L; Chun, Hyung J; Hoyt, Grant; Kutschka, Werner; Pelletier, Marc P; Quertermous, Tom; Wu, Joseph C; Robbins, Robert C

    2007-06-06

    Acquisition of echocardiographic data from rodents is subject to wide variability due to variations in technique. We hypothesize that a dedicated imaging platform can aid in standardization of technique and improve the quality of images obtained. We constructed a device consisting of a boom-mounted steel platform frame (25 x 35 x 3 cm) on which a transparent polyethylene membrane is mounted. The animal is placed onto the membrane and receives continual inhaled anesthesia via an integrated port. The membrane allows for probe positioning from beneath the animal to obtain standard echo-views in left lateral decubitus or prone positions. The frame can be set at any desired angle ranging from 0 to 360 degrees along either the long or short axis. Adult male Sprague-Dawley rats (n = 5) underwent echocardiography (General Electric, Vivid 7, 14 MHz) using the platform. The device allowed for optimal positioning of animals for a variety of standard echocardiographic measurements. Evaluations among all animals showed minimal variability between two different operators and time points. We tested the feasibility of the device for supporting the assessment of cardiac function in a disease model by evaluating a separate cohort of adult male spontaneously hypertensive rats (n = 5) that underwent left anterior descending coronary artery ligation. Serial echocardiography demonstrated statistically significant decreases of fractional shortening and ejection fraction (p rats. Future studies will focus on improving this technology to allow for standardized high-throughput echocardiographic analysis in small animal models of disease.

  9. Toward an E-Government Semantic Platform

    Science.gov (United States)

    Sbodio, Marco Luca; Moulin, Claude; Benamou, Norbert; Barthès, Jean-Paul

    This chapter describes the major aspects of an e-government platform in which semantics underpins more traditional technologies in order to enable new capabilities and to overcome technical and cultural challenges. The design and development of such an e-government Semantic Platform has been conducted with the financial support of the European Commission through the Terregov research project: "Impact of e-government on Territorial Government Services" (Terregov 2008). The goal of this platform is to let local government and government agencies offer online access to their services in an interoperable way, and to allow them to participate in orchestrated processes involving services provided by multiple agencies. Implementing a business process through an electronic procedure is indeed a core goal in any networked organization. However, the field of e-government brings specific constraints to the operations allowed in procedures, especially concerning the flow of private citizens' data: because of legal reasons in most countries, such data are allowed to circulate only from agency to agency directly. In order to promote transparency and responsibility in e-government while respecting the specific constraints on data flows, Terregov supports the creation of centrally controlled orchestrated processes; while the cross agencies data flows are centrally managed, data flow directly across agencies.

  10. Platform Architecture for Decentralized Positioning Systems.

    Science.gov (United States)

    Kasmi, Zakaria; Norrdine, Abdelmoumen; Blankenbach, Jörg

    2017-04-26

    A platform architecture for positioning systems is essential for the realization of a flexible localization system, which interacts with other systems and supports various positioning technologies and algorithms. The decentralized processing of a position enables pushing the application-level knowledge into a mobile station and avoids the communication with a central unit such as a server or a base station. In addition, the calculation of the position on low-cost and resource-constrained devices presents a challenge due to the limited computing, storage capacity, as well as power supply. Therefore, we propose a platform architecture that enables the design of a system with the reusability of the components, extensibility (e.g., with other positioning technologies) and interoperability. Furthermore, the position is computed on a low-cost device such as a microcontroller, which simultaneously performs additional tasks such as data collecting or preprocessing based on an operating system. The platform architecture is designed, implemented and evaluated on the basis of two positioning systems: a field strength system and a time of arrival-based positioning system.

  11. Updating the Micro-Tom TILLING platform.

    Science.gov (United States)

    Okabe, Yoshihiro; Ariizumi, Tohru; Ezura, Hiroshi

    2013-03-01

    The dwarf tomato variety Micro-Tom is regarded as a model system for functional genomics studies in tomato. Various tomato genomic tools in the genetic background of Micro-Tom have been established, such as mutant collections, genome information and a metabolomic database. Recent advances in tomato genome sequencing have brought about a significant need for reverse genetics tools that are accessible to the larger community, because a great number of gene sequences have become available from public databases. To meet the requests from the tomato research community, we have developed the Micro-Tom Targeting-Induced Local Lesions IN Genomes (TILLING) platform, which is comprised of more than 5000 EMS-mutagenized lines. The platform serves as a reverse genetics tool for efficiently identifying mutant alleles in parallel with the development of Micro-Tom mutant collections. The combination of Micro-Tom mutant libraries and the TILLING approach enables researchers to accelerate the isolation of desirable mutants for unraveling gene function or breeding. To upgrade the genomic tool of Micro-Tom, the development of a new mutagenized population is underway. In this paper, the current status of the Micro-Tom TILLING platform and its future prospects are described.

  12. Year 2 Report: Protein Function Prediction Platform

    Energy Technology Data Exchange (ETDEWEB)

    Zhou, C E

    2012-04-27

    Upon completion of our second year of development in a 3-year development cycle, we have completed a prototype protein structure-function annotation and function prediction system: Protein Function Prediction (PFP) platform (v.0.5). We have met our milestones for Years 1 and 2 and are positioned to continue development in completion of our original statement of work, or a reasonable modification thereof, in service to DTRA Programs involved in diagnostics and medical countermeasures research and development. The PFP platform is a multi-scale computational modeling system for protein structure-function annotation and function prediction. As of this writing, PFP is the only existing fully automated, high-throughput, multi-scale modeling, whole-proteome annotation platform, and represents a significant advance in the field of genome annotation (Fig. 1). PFP modules perform protein functional annotations at the sequence, systems biology, protein structure, and atomistic levels of biological complexity (Fig. 2). Because these approaches provide orthogonal means of characterizing proteins and suggesting protein function, PFP processing maximizes the protein functional information that can currently be gained by computational means. Comprehensive annotation of pathogen genomes is essential for bio-defense applications in pathogen characterization, threat assessment, and medical countermeasure design and development in that it can short-cut the time and effort required to select and characterize protein biomarkers.

  13. 21 CFR 890.3940 - Wheelchair platform scale.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Wheelchair platform scale. 890.3940 Section 890...) MEDICAL DEVICES PHYSICAL MEDICINE DEVICES Physical Medicine Prosthetic Devices § 890.3940 Wheelchair platform scale. (a) Identification. A wheelchair platform scale is a device with a base designed...

  14. On the notion of abstract platform in MDA development

    NARCIS (Netherlands)

    Andrade Almeida, João; Dijkman, R.M.; van Sinderen, Marten J.; Ferreira Pires, Luis

    2004-01-01

    Although platform-independence is a central property in MDA models, the study of platform-independence has been largely overlooked in MDA. As a consequence, there is a lack of guidelines to select abstraction criteria and modelling concepts for platform-independent design. In addition, there is

  15. Tethered acoustic doppler current profiler platforms for measuring streamflow

    Science.gov (United States)

    Rehmel, Michael S.; Stewart, James A.; Morlock, Scott E.

    2003-01-01

    The U.S. Geological Survey tested and refined tethered-platform designs for measuring streamflow. Platform specifications were developed, radio-modem telemetry of acoustic Doppler current profiler (ADCP) data and potential platform-hull sources were investigated, and hulls were tested and evaluated.

  16. On the Notion of Abstract Platform in MDA Development

    NARCIS (Netherlands)

    Almeida, João Paulo; Dijkman, Remco; Sinderen, van Marten; Ferreira Pires, Luis

    2004-01-01

    Although platform-independence is a central property in MDA models, the study of platform-independence has been largely overlooked in MDA. As a consequence, there is a lack of guidelines to select abstraction criteria and modelling concepts for platform-independent design. In addition, there is litt

  17. Product platform life cycles : a multiple case study

    NARCIS (Netherlands)

    Wortmann, Hans; Alblas, Alex

    2009-01-01

    Product platforms are used to specify a (virtual) company's offering to the market in terms of functionality and performance. The specification covers a rang e of actual products and services and the platform includes choice features, options and external interfaces. Usually, the platform also

  18. Picture Compilation in Multi-Platform Sensor Networks

    NARCIS (Netherlands)

    Theil, A.; Bergmans, J.; Broek, S.P. van den; Huizing, A.G.; Kester, L.J.H.M.

    2006-01-01

    The traditional approach to maritime operations in open ocean conditions (‘blue waters’) is platform centric. In this approach, an environmental picture is generated on each platform separately. High quality tracks can be made available to other platforms through classic data links, e.g. Link 11 and

  19. D3.2a Final ECO Platform Architecture Design

    NARCIS (Netherlands)

    Loozen, Kjeld; Viñuales, Javier; Ternier, Stefaan

    2016-01-01

    This deliverable presents the ECO platform architecture. It reports on the outcomes of the work so far conducted under task T3.2: Overall platform architecture. It specifies all components that will constitute the ECO platform and describes the connection to each other.

  20. Complementor embeddedness in platform ecosystems : The case of google apps

    NARCIS (Netherlands)

    Angeren, van J.; Blijleven, V.B; Jansen, S.; Brinkkemper, S.

    2013-01-01

    Platforms and their marketplaces with complementarities are prominent in the software industry. As the proprietary platform itself exhibits elementary or generic functionality, platform owners depend on a complementor ecosystem populated by third-parties. At present, little is known about mechanisms

  1. Product platform life cycles : a multiple case study

    NARCIS (Netherlands)

    Wortmann, Hans; Alblas, Alex

    2009-01-01

    Product platforms are used to specify a (virtual) company's offering to the market in terms of functionality and performance. The specification covers a rang e of actual products and services and the platform includes choice features, options and external interfaces. Usually, the platform also speci

  2. Towards a service platform for mobile context-aware applications

    NARCIS (Netherlands)

    Dockhorn Costa, P.; Ferreira Pires, L.; Sinderen, van M.J.; Pereira Filho, J.G.; Mostefaoui, S.K.; Maarmar, Z.; Rana, O.F.

    2004-01-01

    Context-aware services platforms aim at supporting the handling of contextual information in order to provide better user-tailored services. This paper proposes a novel services platform architecture to support mobile context-aware applications, giving emphasis to the configurability of the platform

  3. GEMBus based services composition platform for cloud PaaS

    NARCIS (Netherlands)

    Demchenko, Y.; Ngo, C.; Martínez-Julia, P.; Torroglosa, E.; Grammatikou, M.; Jofre, J.; Gheorghiu, S.; Garcia-Espin, J.A.; Perez-Morales, A.D.; de Laat, C.

    2012-01-01

    Cloud Platform as a Service (PaaS) provides an environment for creating and deploying applications using one of popular development platforms. This paper presents a practical solution for building a service composition platform based on the GEMBus (GEANT Multi-domain Bus) that extends the industry a

  4. D3.2a Final ECO Platform Architecture Design

    NARCIS (Netherlands)

    Loozen, Kjeld; Viñuales, Javier; Ternier, Stefaan

    2016-01-01

    This deliverable presents the ECO platform architecture. It reports on the outcomes of the work so far conducted under task T3.2: Overall platform architecture. It specifies all components that will constitute the ECO platform and describes the connection to each other.

  5. Stress analysis of portable safety platform (Core Sampler Truck)

    Energy Technology Data Exchange (ETDEWEB)

    Ziada, H.H.

    1995-03-30

    This document provides the stress analysis and evaluation of the portable platform of the rotary mode core sampler truck No. 2 (RMCST {number_sign}2). The platform comprises railing, posts, deck, legs, and a portable ladder; it is restrained from lateral motion by means of two brackets added to the drill-head service platform.

  6. Superhydrophobic surface-enhanced Raman scattering platform fabricated by assembly of Ag nanocubes for trace molecular sensing.

    Science.gov (United States)

    Lee, Hiang Kwee; Lee, Yih Hong; Zhang, Qi; Phang, In Yee; Tan, Joel Ming Rui; Cui, Yan; Ling, Xing Yi

    2013-11-13

    An analytical platform suitable for trace detection using a small volume of analyte is pertinent to the field of toxin detection and criminology. Plasmonic nanostructures provide surface-enhanced Raman scattering (SERS) that can potentially achieve trace toxins and/or molecules detection. However, the detection of highly diluted, small volume samples remains a challenge. Here, we fabricate a superhydrophobic SERS platform by assembling Ag nanocubes that support strong surface plasmon and chemical functionalization for trace detection with sample volume of just 1 μL. Our strategy integrates the intense electromagnetic field confinement generated by Ag nanocubes with a superhydrophobic surface capable of analyte concentration to lower the molecular detection limit. Single crystalline Ag nanocubes are assembled using the Langmuir-Blodgett technique to create surface roughness. To create a stable superhydrophobic SERS platform, an additional 25 nm Ag coating is evaporated over the Ag nanocubes to "weld" the Ag nanocubes onto the substrate followed by chemical functionalization with perfluorodecanethiol. The resulting substrate has an advancing contact angle of 169° ± 5°. Our superhydrophobic platform confines analyte molecules within a small area and prevents the random spreading of molecules. An analyte concentrating factor of 14-fold is attained, as compared to a hydrophilic surface. Consequently, the detection limit of our superhydrophobic SERS substrate reaches 10(-16) M (100 aM) for rhodamine 6G using 1 μL analyte solutions. An analytical SERS enhancement factor of 10(11) is achieved. Our protocol is a general method that provides a simple, cost-effective approach to develop a stable and uniform superhydrophobic SERS platform for trace molecular sensing.

  7. Oil and Gas Producing Platforms in the Gulf of Mexico, Geographic NAD83, MMS (1998)[platforms_MMS_1998

    Data.gov (United States)

    Louisiana Geographic Information Center — This is a point data set for the location of over 4300 MMS administered platform structures used for oil and gas production in the Gulf of Mexico. Groups of platform...

  8. Towards rapid prototyped convective microfluidic DNA amplification platform

    Science.gov (United States)

    Ajit, Smrithi; Praveen, Hemanth Mithun; Puneeth, S. B.; Dave, Abhishek; Sesham, Bharat; Mohan, K. N.; Goel, Sanket

    2017-02-01

    Today, Polymerase Chain Reaction (PCR) based DNA amplification plays an indispensable role in the field of biomedical research. Its inherent ability to exponentially amplify sample DNA has proven useful for the identification of virulent pathogens like those causing Multiple Drug-Resistant Tuberculosis (MDR-TB). The intervention of Microfluidics technology has revolutionized the concept of PCR from being a laborious and time consuming process into one that is faster, easily portable and capable of being multifunctional. The Microfluidics based PCR outweighs its traditional counterpart in terms of flexibility of varying reaction rate, operation simplicity, need of a fraction of volume and capability of being integrated with other functional elements. The scope of the present work involves the development of a real-time continuous flow microfluidic device, fabricated by 3D printing-governed rapid prototyping method, eventually leading to an automated and robust platform to process multiple DNA samples for detection of MDRTB-associated mutations. The thermal gradient characteristic to the PCR process is produced using peltier units appropriate to the microfluidic environment fully monitored and controlled by a low cost controller driven by a Data Acquisition System. The process efficiency achieved in the microfluidic environment in terms of output per cycle is expected to be on par with the traditional PCR and capable of earning the additional advantages of being faster and minimizing the handling.

  9. Porous-Hybrid Polymers as Platforms for Heterogeneous Photochemical Catalysis

    KAUST Repository

    Haikal, Rana R.

    2016-07-18

    A number of permanently porous polymers containing Ru(bpy)n photosensitizer or a cobaloxime complex, as a proton-reduction catalyst, were constructed via one-pot Sonogashira-Hagihara (SH) cross-coupling reactions. This process required minimal workup to access porous platforms with control over the apparent surface area, pore volume, and chemical functionality from suitable molecular building blocks (MBBs) containing the Ru or Co complexes, as rigid and multi-topic nodes. The cobaloxime molecular building block, generated through in situ metalation, afforded a microporous solid that demonstrated noticeable catalytic activity towards hydrogen-evolution reaction (HER) with remarkable recyclability. We further demonstrated, in two cases, the ability to affect the excited state lifetime of the covalently-immobilized Ru(bpy)3 complex attained through deliberate utilization of the organic linkers of variable dimensions. Overall, this approach facilitates construction of tunable porous solids, with hybrid composition and pronounced chemical and physical stability, based on the well-known Ru(bpy)nor the cobaloxime complexes.

  10. Component Reliability Assessment of Offshore Jacket Platforms

    Directory of Open Access Journals (Sweden)

    V.J. Kurian

    2015-01-01

    Full Text Available Oil and gas industry is one of the most important industries contributing to the Malaysian economy. To extract hydrocarbons, various types of production platforms have been developed. Fixed jacket platform is the earliest type of production structure, widely installed in Malaysia’s shallow and intermediate waters. To date, more than 60% of these jacket platforms have operated exceeding their initial design life, thus making the re-evaluation and reassessment necessary for these platforms to continue to be put in service. In normal engineering practice, system reliability of a structure is evaluated as its safety parameter. This method is however, much complicated and time consuming. Assessing component's reliability can be an alternative approach to provide assurance about a structure’s condition in an early stage. Design codes such as the Working Stress Design (WSD and the Load and Resistance Factor Design (LRFD are well established for the component-level assessment. In reliability analysis, failure function, which consists of strength and load, is used to define the failure event. If the load acting exceeds the capacity of a structure, the structure will fail. Calculation of stress utilization ratio as given in the design codes is able to predict the reliability of a member and to estimate the extent to which a member is being utilised. The basic idea of this ratio is that if it is more than one, the member has failed and vice versa. Stress utilization ratio is a ratio of applied stress, which is the output reaction of environmental loadings acting on the structural member, to the design strength that comes from the member’s geometric and material properties. Adopting this ratio as the failure event, the reliability of each component is found. This study reviews and discusses the reliability for selected members of three Malaysian offshore jacket platforms. First Order Reliability Method (FORM was used to generate reliability index and

  11. A Model Collaborative Platform for Geoscience Education

    Science.gov (United States)

    Fox, S.; Manduca, C. A.; Iverson, E. A.

    2012-12-01

    Over the last decade SERC at Carleton College has developed a collaborative platform for geoscience education that has served dozens of projects, thousands of community authors and millions of visitors. The platform combines a custom technical infrastructure: the SERC Content Management system (CMS), and a set of strategies for building web-resources that can be disseminated through a project site, reused by other projects (with attribution) or accessed via an integrated geoscience education resource drawing from all projects using the platform. The core tools of the CMS support geoscience education projects in building project-specific websites. Each project uses the CMS to engage their specific community in collecting, authoring and disseminating the materials of interest to them. At the same time the use of a shared central infrastructure allows cross-fertilization among these project websites. Projects are encouraged to use common templates and common controlled vocabularies for organizing and displaying their resources. This standardization is then leveraged through cross-project search indexing which allow projects to easily incorporate materials from other projects within their own collection in ways that are relevant and automated. A number of tools are also in place to help visitors move among project websites based on their personal interests. Related links help visitors discover content related topically to their current location that is in a 'separate' project. A 'best bets' feature in search helps guide visitors to pages that are good starting places to explore resources on a given topic across the entire range of hosted projects. In many cases these are 'site guide' pages created specifically to promote a cross-project view of the available resources. In addition to supporting the cross-project exploration of specific themes the CMS also allows visitors to view the combined suite of resources authored by any particular community member. Automatically

  12. Geospatial Data Management Platform for Urban Groundwater

    Science.gov (United States)

    Gaitanaru, D.; Priceputu, A.; Gogu, C. R.

    2012-04-01

    Due to the large amount of civil work projects and research studies, large quantities of geo-data are produced for the urban environments. These data are usually redundant as well as they are spread in different institutions or private companies. Time consuming operations like data processing and information harmonisation represents the main reason to systematically avoid the re-use of data. The urban groundwater data shows the same complex situation. The underground structures (subway lines, deep foundations, underground parkings, and others), the urban facility networks (sewer systems, water supply networks, heating conduits, etc), the drainage systems, the surface water works and many others modify continuously. As consequence, their influence on groundwater changes systematically. However, these activities provide a large quantity of data, aquifers modelling and then behaviour prediction can be done using monitored quantitative and qualitative parameters. Due to the rapid evolution of technology in the past few years, transferring large amounts of information through internet has now become a feasible solution for sharing geoscience data. Furthermore, standard platform-independent means to do this have been developed (specific mark-up languages like: GML, GeoSciML, WaterML, GWML, CityML). They allow easily large geospatial databases updating and sharing through internet, even between different companies or between research centres that do not necessarily use the same database structures. For Bucharest City (Romania) an integrated platform for groundwater geospatial data management is developed under the framework of a national research project - "Sedimentary media modeling platform for groundwater management in urban areas" (SIMPA) financed by the National Authority for Scientific Research of Romania. The platform architecture is based on three components: a geospatial database, a desktop application (a complex set of hydrogeological and geological analysis

  13. Proba-V Mission Exploitation Platform

    Science.gov (United States)

    Goor, Erwin; Dries, Jeroen

    2017-04-01

    VITO and partners developed the Proba-V Mission Exploitation Platform (MEP) as an end-to-end solution to drastically improve the exploitation of the Proba-V (a Copernicus contributing mission) EO-data archive (http://proba-v.vgt.vito.be/), the past mission SPOT-VEGETATION and derived vegetation parameters by researchers, service providers and end-users. The analysis of time series of data (+1PB) is addressed, as well as the large scale on-demand processing of near real-time data on a powerful and scalable processing environment. Furthermore data from the Copernicus Global Land Service is in scope of the platform. From November 2015 an operational Proba-V MEP environment, as an ESA operation service, is gradually deployed at the VITO data center with direct access to the complete data archive. Since autumn 2016 the platform is operational and yet several applications are released to the users, e.g. - A time series viewer, showing the evolution of Proba-V bands and derived vegetation parameters from the Copernicus Global Land Service for any area of interest. - Full-resolution viewing services for the complete data archive. - On-demand processing chains on a powerfull Hadoop/Spark backend e.g. for the calculation of N-daily composites. - Virtual Machines can be provided with access to the data archive and tools to work with this data, e.g. various toolboxes (GDAL, QGIS, GrassGIS, SNAP toolbox, …) and support for R and Python. This allows users to immediately work with the data without having to install tools or download data, but as well to design, debug and test applications on the platform. - A prototype of jupyter Notebooks is available with some examples worked out to show the potential of the data. Today the platform is used by several third party projects to perform R&D activities on the data, and to develop/host data analysis toolboxes. In parallel the platform is further improved and extended. From the MEP PROBA-V, access to Sentinel-2 and landsat data will

  14. Methodology for development of risk indicators for offshore platforms

    Energy Technology Data Exchange (ETDEWEB)

    Oeien, K.; Sklet, S. [SINTEF Industrial Management Safety and Reliability (Norway)

    1999-09-01

    This paper presents a generic methodology for development of risk indicators for petroleum installations and a specific set of risk indicators established for one offshore platform. The risk indicators should be used to control the risk during operation of platforms. The methodology is purely risk-based and the basis for development of risk indicators is the platform specific quantitative risk analysis (QRA). In order to identify high risk contributing factors, platform personnel are asked to assess whether and how much the risk influencing factors will change. A brief comparison of probabilistic safety assessment (PSA) for nuclear power plants and quantitative risk analysis (QRA) for petroleum platforms is also given. (au)

  15. The development of an open platform to test ITS solutions

    DEFF Research Database (Denmark)

    Lahrmann, Harry; Agerholm, Niels; Juhl, Jens

    2013-01-01

    This paper presents the ITS Platform Northern Denmark, which is an open platform to test ITS solutions. The platform consists of a new developed GNSS/GPRS On Board Unit installed in nearly 500 cars, a backend server and a specially designed digital road map for ITS applications. The platform...... is open for third part application. This paper presents the platform’s potentials and explains a series of test applications, which are developed on the plat- form. Moreover, a number of new projects, which are planned for ITS Platform is introduced....

  16. Carbonate platform growth and demise offshore Central Vietnam

    DEFF Research Database (Denmark)

    Fyhn, Michael B.W.; Boldreel, Lars Ole; Nielsen, Lars H.;

    2013-01-01

    Fault Zone, the Tuy Hoa Carbonate Platform fringes the continental margin between Da Nang and Nha Trang. Here, platform growth initiated during the Early Miocene and continued until Middle Miocene time when regional uplift led to subaerial exposure, termination of platform growth and karstification...... is interpreted as a consequence of regional uplift and denudation of central and south Indochina starting during Middle Miocene time when the Tuy Hoa Carbonate Platform became subaerially exposed. Stressed carbonate growth conditions on the Triton Carbonate Platform probably resulted from increased inorganic...

  17. Postoperative volume balance

    DEFF Research Database (Denmark)

    Frost, H; Mortensen, C.R.; Secher, Niels H.

    2017-01-01

    In healthy humans, stroke volume (SV) and cardiac output (CO) do not increase with expansion of the central blood volume by head-down tilt or administration of fluid. Here, we exposed 85 patients to Trendelenburg's position about one hour after surgery while cardiovascular variables were determined...... non-invasively by Modelflow. In Trendelenburg's position, SV (83 ± 19 versus 89 ± 20 ml) and CO (6·2 ± 1·8 versus 6·8 ± 1·8 l/min; both Pheart rate (75 ± 15 versus 76 ± 14 b min(-1) ) and mean arterial pressure were unaffected (84 ± 15 versus 84 ± 16 mmHg). For the 33 patients......, determination of SV and/or CO in Trendelenburg's position can be used to evaluate whether a patient is in need of IV fluid as here exemplified after surgery....

  18. Select Papers. Volume 1

    Science.gov (United States)

    2011-08-01

    non- uniform rational B-splines (NURBS), 127 and BRL-CAD TM format. This dual-package development allowed for rapid development of components ...next generation of scientists and engineers. A fundamental component of our outreach program is to provide students research experiences at ARL...summer intern. There, I ran Volume Based Morphometry , an application of Statistical Parametric Mapping that was new to the Hirsch lab. I

  19. Airborne X-band SAR tomography for forest volumes

    Science.gov (United States)

    Muirhead, Fiona; Woodhouse, Iain H.; Mulgrew, Bernard

    2016-10-01

    We evaluate the usefulness of X-band, airborne (helicopter) data for tomography over forestry regions and discuss the use of compressive sensing algorithms to aid X-band airborne tomography. This work examines if there is any information that can be gained from forest volumes when analysing forestry sites using X-band data. To do so, different forest scenarios were simulated and a fast SAR simulator was used to model airborne multipass SAR data, at X-band, with parameters based on Leonardo's PicoSAR instrument. Model simulations considered varying factors that affect the height determination when using tomography. The main parameters that are considered here are: motion errors of the platform, the spacing of the flight paths, the resolution of the SAR images and plant life being present under the canopy (an understory). It was found that residual motion errors from the airborne platform cause the largest error in the tomographic profile.

  20. Small-Volume Injections: Evaluation of Volume Administration Deviation From Intended Injection Volumes.

    Science.gov (United States)

    Muffly, Matthew K; Chen, Michael I; Claure, Rebecca E; Drover, David R; Efron, Bradley; Fitch, William L; Hammer, Gregory B

    2017-10-01

    In the perioperative period, anesthesiologists and postanesthesia care unit (PACU) nurses routinely prepare and administer small-volume IV injections, yet the accuracy of delivered medication volumes in this setting has not been described. In this ex vivo study, we sought to characterize the degree to which small-volume injections (≤0.5 mL) deviated from the intended injection volumes among a group of pediatric anesthesiologists and pediatric postanesthesia care unit (PACU) nurses. We hypothesized that as the intended injection volumes decreased, the deviation from those intended injection volumes would increase. Ten attending pediatric anesthesiologists and 10 pediatric PACU nurses each performed a series of 10 injections into a simulated patient IV setup. Practitioners used separate 1-mL tuberculin syringes with removable 18-gauge needles (Becton-Dickinson & Company, Franklin Lakes, NJ) to aspirate 5 different volumes (0.025, 0.05, 0.1, 0.25, and 0.5 mL) of 0.25 mM Lucifer Yellow (LY) fluorescent dye constituted in saline (Sigma Aldrich, St. Louis, MO) from a rubber-stoppered vial. Each participant then injected the specified volume of LY fluorescent dye via a 3-way stopcock into IV tubing with free-flowing 0.9% sodium chloride (10 mL/min). The injected volume of LY fluorescent dye and 0.9% sodium chloride then drained into a collection vial for laboratory analysis. Microplate fluorescence wavelength detection (Infinite M1000; Tecan, Mannedorf, Switzerland) was used to measure the fluorescence of the collected fluid. Administered injection volumes were calculated based on the fluorescence of the collected fluid using a calibration curve of known LY volumes and associated fluorescence.To determine whether deviation of the administered volumes from the intended injection volumes increased at lower injection volumes, we compared the proportional injection volume error (loge [administered volume/intended volume]) for each of the 5 injection volumes using a linear

  1. Risk Management of P2P Internet Financing Service Platform

    Science.gov (United States)

    Yalei, Li

    2017-09-01

    Since 2005, the world’s first P2P Internet financing service platform Zopa in UK was introduced, in the development of “Internet +” trend, P2P Internet financing service platform has been developed rapidly. In 2007, China’s first P2P platform “filming loan” was established, marking the P2P Internet financing service platform to enter China and the rapid development. At the same time, China’s P2P Internet financing service platform also appeared in different forms of risk. This paper focuses on the analysis of the causes of risk of P2P Internet financing service platform and the performance of risk management process. It provides a solution to the Internet risk management plan, and explains the risk management system of the whole P2P Internet financing service platform and the future development direction.

  2. NCI's Transdisciplinary High Performance Scientific Data Platform

    Science.gov (United States)

    Evans, Ben; Antony, Joseph; Bastrakova, Irina; Car, Nicholas; Cox, Simon; Druken, Kelsey; Evans, Bradley; Fraser, Ryan; Ip, Alex; Kemp, Carina; King, Edward; Minchin, Stuart; Larraondo, Pablo; Pugh, Tim; Richards, Clare; Santana, Fabiana; Smillie, Jon; Trenham, Claire; Wang, Jingbo; Wyborn, Lesley

    2016-04-01

    The Australian National Computational Infrastructure (NCI) manages Earth Systems data collections sourced from several domains and organisations onto a single High Performance Data (HPD) Node to further Australia's national priority research and innovation agenda. The NCI HPD Node has rapidly established its value, currently managing over 10 PBytes of datasets from collections that span a wide range of disciplines including climate, weather, environment, geoscience, geophysics, water resources and social sciences. Importantly, in order to facilitate broad user uptake, maximise reuse and enable transdisciplinary access through software and standardised interfaces, the datasets, associated information systems and processes have been incorporated into the design and operation of a unified platform that NCI has called, the National Environmental Research Data Interoperability Platform (NERDIP). The key goal of the NERDIP is to regularise data access so that it is easily discoverable, interoperable for different domains and enabled for high performance methods. It adopts and implements international standards and data conventions, and promotes scientific integrity within a high performance computing and data analysis environment. NCI has established a rich and flexible computing environment to access to this data, through the NCI supercomputer; a private cloud that supports both domain focused virtual laboratories and in-common interactive analysis interfaces; as well as remotely through scalable data services. Data collections of this importance must be managed with careful consideration of both their current use and the needs of the end-communities, as well as its future potential use, such as transitioning to more advanced software and improved methods. It is therefore critical that the data platform is both well-managed and trusted for stable production use (including transparency and reproducibility), agile enough to incorporate new technological advances and

  3. Intelligent tools for building a scientific information platform advanced architectures and solutions

    CERN Document Server

    Skonieczny, Lukasz; Rybinski, Henryk; Kryszkiewicz, Marzena; Niezgodka, Marek

    2013-01-01

    This book is a selection of results obtained within two years of research per- formed under SYNAT - a nation-wide scientific project aiming at creating an infrastructure for scientific content storage and sharing for academia, education and open knowledge society in Poland. The selection refers to the research in artificial intelligence, knowledge discovery and data mining, information retrieval and natural language processing, addressing the problems of implementing intelligent tools for building a scientific information platform.This book is a continuation and extension of the ideas presented in “Intelligent Tools for Building a Scientific Information Platform” published as volume 390 in the same series in 2012. It is based on the SYNAT 2012 Workshop held in Warsaw. The papers included in this volume present an overview and insight into information retrieval, repository systems, text processing, ontology-based systems, text mining, multimedia data processing and advanced software engineering.  

  4. ASTROMLSKIT: A New Statistical Machine Learning Toolkit: A Platform for Data Analytics in Astronomy

    CERN Document Server

    Saha, Snehanshu; R, Manikandan; Bora, Kakoli; Routh, Swati; Narasimhamurthy, Anand

    2015-01-01

    Astroinformatics is a new impact area in the world of astronomy, occasionally called the final frontier, where several astrophysicists, statisticians and computer scientists work together to tackle various data intensive astronomical problems. Exponential growth in the data volume and increased complexity of the data augments difficult questions to the existing challenges. Classical problems in Astronomy are compounded by accumulation of astronomical volume of complex data, rendering the task of classification and interpretation incredibly laborious. The presence of noise in the data makes analysis and interpretation even more arduous. Machine learning algorithms and data analytic techniques provide the right platform for the challenges posed by these problems. A diverse range of open problem like star-galaxy separation, detection and classification of exoplanets, classification of supernovae is discussed. The focus of the paper is the applicability and efficacy of various machine learning algorithms like K N...

  5. Droplet-based microfluidic platforms for the encapsulation and screening of Mammalian cells and multicellular organisms.

    Science.gov (United States)

    Clausell-Tormos, Jenifer; Lieber, Diana; Baret, Jean-Christophe; El-Harrak, Abdeslam; Miller, Oliver J; Frenz, Lucas; Blouwolff, Joshua; Humphry, Katherine J; Köster, Sarah; Duan, Honey; Holtze, Christian; Weitz, David A; Griffiths, Andrew D; Merten, Christoph A

    2008-05-01

    High-throughput, cell-based assays require small sample volumes to reduce assay costs and to allow for rapid sample manipulation. However, further miniaturization of conventional microtiter plate technology is problematic due to evaporation and capillary action. To overcome these limitations, we describe droplet-based microfluidic platforms in which cells are grown in aqueous microcompartments separated by an inert perfluorocarbon carrier oil. Synthesis of biocompatible surfactants and identification of gas-permeable storage systems allowed human cells, and even a multicellular organism (C. elegans), to survive and proliferate within the microcompartments for several days. Microcompartments containing single cells could be reinjected into a microfluidic device after incubation to measure expression of a reporter gene. This should open the way for high-throughput, cell-based screening that can use >1000-fold smaller assay volumes and has approximately 500x higher throughput than conventional microtiter plate assays.

  6. Intelligent tools for building a scientific information platform from research to implementation

    CERN Document Server

    Skonieczny, Łukasz; Rybiński, Henryk; Kryszkiewicz, Marzena; Niezgódka, Marek

    2014-01-01

    This book is a selection of results obtained within three years of research performed under SYNAT—a nation-wide scientific project aiming at creating an infrastructure for scientific content storage and sharing for academia, education and open knowledge society in Poland. The book is intended to be the last of the series related to the SYNAT project. The previous books, titled “Intelligent Tools for Building a Scientific Information Platform” and “Intelligent Tools for Building a Scientific Information Platform: Advanced Architectures and Solutions”, were published as volumes 390 and 467 in Springer's Studies in Computational Intelligence. Its contents is based on the SYNAT 2013 Workshop held in Warsaw. The papers included in this volume present an overview and insight into information retrieval, repository systems, text processing, ontology-based systems, text mining, multimedia data processing and advanced software engineering, addressing the problems of implementing intelligent tools for building...

  7. Disposable cartridge biosensor platform for portable diagnostics

    Science.gov (United States)

    Yaras, Yusuf S.; Cakmak, Onur; Gunduz, Ali B.; Saglam, Gokhan; Olcer, Selim; Mostafazadeh, Aref; Baris, Ibrahim; Civitci, Fehmi; Yaralioglu, Goksen G.; Urey, Hakan

    2017-03-01

    We developed two types of cantilever-based biosensors for portable diagnostics applications. One sensor is based on MEMS cantilever chip mounted in a microfluidic channel and the other sensor is based on a movable optical fiber placed across a microfluidic channel. Both types of sensors were aimed at direct mechanical measurement of coagulation time in a disposable cartridge using plasma or whole blood samples. There are several similarities and also some important differences between the MEMS based and the optical fiber based solutions. The aim of this paper is to provide a comparison between the two solutions and the results. For both types of sensors, actuation of the cantilever or the moving fiber is achieved using an electro coil and the readout is optical. Since both the actuation and sensing are remote, no electrical connections are required for the cartridge. Therefore it is possible to build low cost disposable cartridges. The reader unit for the cartridge contains light sources, photodetectors, the electro coil, a heater, analog electronics, and a microprocessor. The reader unit has different optical interfaces for the cartridges that have MEMS cantilevers and moving fibers. MEMS based platform has better sensitivity but optomechanical alignment is a challenge and measurements with whole blood were not possible due to high scattering of light by the red blood cells. Fiber sensor based platform has relaxed optomechanical tolerances, ease of manufacturing, and it allows measurements in whole blood. Both sensors were tested using control plasma samples for activated-Partial-Thromboplastin-Time (aPTT) measurements. Control plasma test results matched with the manufacturer's datasheet. Optical fiber based system was tested for aPTT tests with human whole blood samples and the proposed platform provided repeatable test results making the system method of choice for portable diagnostics.

  8. Seqcrawler: biological data indexing and browsing platform

    Directory of Open Access Journals (Sweden)

    Sallou Olivier

    2012-07-01

    Full Text Available Abstract Background Seqcrawler takes its roots in software like SRS or Lucegene. It provides an indexing platform to ease the search of data and meta-data in biological banks and it can scale to face the current flow of data. While many biological bank search tools are available on the Internet, mainly provided by large organizations to search their data, there is a lack of free and open source solutions to browse one’s own set of data with a flexible query system and able to scale from a single computer to a cloud system. A personal index platform will help labs and bioinformaticians to search their meta-data but also to build a larger information system with custom subsets of data. Results The software is scalable from a single computer to a cloud-based infrastructure. It has been successfully tested in a private cloud with 3 index shards (pieces of index hosting ~400 millions of sequence information (whole GenBank, UniProt, PDB and others for a total size of 600 GB in a fault tolerant architecture (high-availability. It has also been successfully integrated with software to add extra meta-data from blast results to enhance users’ result analysis. Conclusions Seqcrawler provides a complete open source search and store solution for labs or platforms needing to manage large amount of data/meta-data with a flexible and customizable web interface. All components (search engine, visualization and data storage, though independent, share a common and coherent data system that can be queried with a simple HTTP interface. The solution scales easily and can also provide a high availability infrastructure.

  9. Biodiversity information platforms: From standards to interoperability

    Directory of Open Access Journals (Sweden)

    Walter Berendsohn

    2011-11-01

    Full Text Available One of the most serious bottlenecks in the scientific workflows of biodiversity sciences is the need to integrate data from different sources, software applications, and services for analysis, visualisation and publication. For more than a quarter of a century the TDWG Biodiversity Information Standards organisation has a central role in defining and promoting data standards and protocols supporting interoperability between disparate and locally distributed systems. Although often not sufficiently recognized, TDWG standards are the foundation of many popular Biodiversity Informatics applications and infrastructures ranging from small desktop software solutions to large scale international data networks. However, individual scientists and groups of collaborating scientist have difficulties in fully exploiting the potential of standards that are often notoriously complex, lack non-technical documentations, and use different representations and underlying technologies. In the last few years, a series of initiatives such as Scratchpads, the EDIT Platform for Cybertaxonomy, and biowikifarm have started to implement and set up virtual work platforms for biodiversity sciences which shield their users from the complexity of the underlying standards. Apart from being practical work-horses for numerous working processes related to biodiversity sciences, they can be seen as information brokers mediating information between multiple data standards and protocols. The ViBRANT project will further strengthen the flexibility and power of virtual biodiversity working platforms by building software interfaces between them, thus facilitating essential information flows needed for comprehensive data exchange, data indexing, web-publication, and versioning. This work will make an important contribution to the shaping of an international, interoperable, and user-oriented biodiversity information infrastructure.

  10. Smart SOA platforms in cloud computing architectures

    CERN Document Server

    Exposito , Ernesto

    2014-01-01

    This book is intended to introduce the principles of the Event-Driven and Service-Oriented Architecture (SOA 2.0) and its role in the new interconnected world based on the cloud computing architecture paradigm. In this new context, the concept of "service" is widely applied to the hardware and software resources available in the new generation of the Internet. The authors focus on how current and future SOA technologies provide the basis for the smart management of the service model provided by the Platform as a Service (PaaS) layer.

  11. Analytical laboratory and mobile sampling platform

    Energy Technology Data Exchange (ETDEWEB)

    Stetzenbach, K.; Smiecinski, A.

    1996-04-30

    This is the final report for the Analytical Laboratory and Mobile Sampling Platform project. This report contains only major findings and conclusions resulting from this project. Detailed reports of all activities performed for this project were provided to the Project Office every quarter since the beginning of the project. This report contains water chemistry data for samples collected in the Nevada section of Death Valley National Park (Triangle Area Springs), Nevada Test Site springs, Pahranagat Valley springs, Nevada Test Site wells, Spring Mountain springs and Crater Flat and Amargosa Valley wells.

  12. Determinants of health: a progressive political platform.

    Science.gov (United States)

    Terris, M

    1994-01-01

    This paper is based on the statement in the Ottawa Charter for Health Promotion that "The fundamental conditions and resources for health are peace, shelter, education, food, income, a stable eco-system, sustainable resources, social justice and equity. Improvement in health requires a secure foundation in these basic prerequisites." It attempts to formulate a progressive political platform for a number of these prerequisites, offering a series of recommendations regarding education, employment, income, and housing, and urging that the proposed programs be funded by progressive taxation and major reductions in the military budget.

  13. Effective envelope method for Stewart platform workspace

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The workspace of Stewart platform is the intersection of 6 son workspaces of 6 loop chains, so it is important to determine the boundary of the son workspace when locating the boundary of the son workspace. An effectivc envelope method is proposed in this paper. Firstly the envelope theory of a family of singular parameter curve surfaces is used to find the envelope surfaces of the son workspace. Then the numerical method is applied to determine the effective envelope surface. And after that the full boundary of the son workspace, which is the envelope of the effective envelope surfaces, is determined. Finally the workspace can be obtained with a section plane method.

  14. Building a Community-Focused Data Platform

    Energy Technology Data Exchange (ETDEWEB)

    Turk, Matthew J. [Univ. of Illinois, Urbana-Champaign, IL (United States). National Center for Supercomputing Applications (NCSA); Warren, Michael S. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Skillman, Samuel W. [Stanford Univ., CA (United States)

    2014-06-10

    The National Data Service (NDS) presents a broad-reaching vision of integrating discovery, publishing, and sharing of data. Metcalfe's Law states that the value of a network increases with the number of connections in the network, not the number of nodes. The NDS must develop and steward connections not only between data, as is in its vision statement, but between individuals as well. We propose that this be accomplished by explicitly developing it as a platform on which data exploration can be constructed by individual researchers.

  15. Instant HTMl5 2D platformer

    CERN Document Server

    Temple, Aidan

    2013-01-01

    Filled with practical, step-by-step instructions and clear explanations for the most important and useful tasks. The step-by-step approach taken by this book will show you how to develop a 2D HTML5 platformer-based game that you will be able to publish to multiple devices.This book is great for anyone who has an interest in HTML5 games development, and who already has a basic to intermediate grasp on both the HTML markup and JavaScript programming languages. Therefore, due to this requirement, the book will not discuss the inner workings of either of these languages but will instead attempt to

  16. Europa Science Platforms and Kinetic Energy Probes

    Science.gov (United States)

    Hays, C. C.; Klein, G. A.

    2003-01-01

    This presentation will outline a proposed mission for the Jupiter Icy Moons Orbiter (JIMO). The mission outlined will concentrate on an examination of Europa. Some of the primary science goals for the JIMO mission are: 1) to answer broad science questions, 2) improved knowledge of Jovian system; specifically, lunar geological and geophysical properties, 3) chemical composition of Jovian lunar surfaces and subterranean matter, and 4) the search for life. In order to address these issues, the experiment proposed here will deploy orbiting, surface, and subterranean science platforms.

  17. Cyanobacteria as a platform for biofuel production

    Directory of Open Access Journals (Sweden)

    Nicole E Nozzi

    2013-09-01

    Full Text Available Cyanobacteria have great potential as a platform for biofuel production because of their fast growth, ability to fix carbon dioxide gas, and their genetic tractability. Furthermore they do not require fermentable sugars or arable land for growth and so competition with cropland would be greatly reduced. In this perspective we discuss the challenges and areas for improvement most pertinent for advancing cyanobacterial fuel production, including: improving genetic parts, carbon fixation, metabolic flux, nutrient requirements on a large scale, and photosynthetic efficiency using natural light.

  18. Verification of Slam Methods on Ros Platform

    Directory of Open Access Journals (Sweden)

    Radovan Sivý

    2016-09-01

    Full Text Available The paper deals with the problem of experimental vehicle concept for 3D SLAM method based on data from Kinect device. One part of the paper describes the design, implementation and description of the physical model of the experimental vehicle. The second describes an odometry representation with a mathematical model of the Ackerman steering as well. Next describes the ROS platform, which was determined to solve complex robotic tasks. Last part of the paper contains to the evaluation of the results of 3D mapping and localization in unknown space.

  19. Hybrid Integrated Platforms for Silicon Photonics

    Directory of Open Access Journals (Sweden)

    John E. Bowers

    2010-03-01

    Full Text Available A review of recent progress in hybrid integrated platforms for silicon photonics is presented. Integration of III-V semiconductors onto silicon-on-insulator substrates based on two different bonding techniques is compared, one comprising only inorganic materials, the other technique using an organic bonding agent. Issues such as bonding process and mechanism, bonding strength, uniformity, wafer surface requirement, and stress distribution are studied in detail. The application in silicon photonics to realize high-performance active and passive photonic devices on low-cost silicon wafers is discussed. Hybrid integration is believed to be a promising technology in a variety of applications of silicon photonics.

  20. Offshore platform integration and floatover technology

    CERN Document Server

    Liu, Gengshen

    2017-01-01

    This book discusses offshore platform integration technology, focusing on the floatover methodology and its applications. It also addresses topics related to safety and cost-effectiveness, as well as ensuring the success of a project through careful planning and established detailed operation procedure/working manuals, which are rarely found in the published literature. Unlike other publications in this area, the book not only includes details of technology development, but also presents real project cases in the discussion to make it more comprehensible. Each topic is illustrated with carefully created sketches to show the complex operation procedures. .