WorldWideScience

Sample records for plasma sheet population

  1. Sheet Plasma Produced by Hollow Cathode Discharge

    Institute of Scientific and Technical Information of China (English)

    张龙; 张厚先; 杨宣宗; 冯春华; 乔宾; 王龙

    2003-01-01

    A sheet plasma is produced by a hollow cathode discharge under an axial magnetic field.The plasma is about 40cm in length,4 cm in width and 1cm in thickness.The electron density is about 108cm-3.The hollow cathode is made to be shallow with a large opening,which is different from the ordinary deep hollow cathode.A Langmuir probe is used to detect the plasma.The electron density and the spatial distribution of the plasma change when voltage,pressure and the magnetic field vary.A peak and a data fluctuation at about 200 G-300 G are observed in the variation of electron density(or thickness of the sheet plasma)with the magnetic field.Our work will be helpful in characterizing the sheet plasma and will make the production of dense sheet plasma more controllable.

  2. Thermomechanical processing of plasma sprayed intermetallic sheets

    Energy Technology Data Exchange (ETDEWEB)

    Hajaligol, Mohammad R. (Midlothian, VA); Scorey, Clive (Cheshire, CT); Sikka, Vinod K. (Oak Ridge, TN); Deevi, Seetharama C. (Midlothian, VA); Fleischhauer, Grier (Midlothian, VA); Lilly, Jr., A. Clifton (Chesterfield, VA); German, Randall M. (State College, PA)

    2001-01-01

    A powder metallurgical process of preparing a sheet from a powder having an intermetallic alloy composition such as an iron, nickel or titanium aluminide. The sheet can be manufactured into electrical resistance heating elements having improved room temperature ductility, electrical resistivity, cyclic fatigue resistance, high temperature oxidation resistance, low and high temperature strength, and/or resistance to high temperature sagging. The iron aluminide has an entirely ferritic microstructure which is free of austenite and can include, in weight %, 4 to 32% Al, and optional additions such as .ltoreq.1% Cr, .gtoreq.0.05% Zr .ltoreq.2% Ti, .ltoreq.2% Mo, .ltoreq.1% Ni, .ltoreq.0.75% C, .ltoreq.0.1% B, .ltoreq.1% submicron oxide particles and/or electrically insulating or electrically conductive covalent ceramic particles, .ltoreq.1% rare earth metal, and/or .ltoreq.3% Cu. The process includes forming a non-densified metal sheet by consolidating a powder having an intermetallic alloy composition such as by roll compaction, tape casting or plasma spraying, forming a cold rolled sheet by cold rolling the non-densified metal sheet so as to increase the density and reduce the thickness thereof and annealing the cold rolled sheet. The powder can be a water, polymer or gas atomized powder which is subjecting to sieving and/or blending with a binder prior to the consolidation step. After the consolidation step, the sheet can be partially sintered. The cold rolling and/or annealing steps can be repeated to achieve the desired sheet thickness and properties. The annealing can be carried out in a vacuum furnace with a vacuum or inert atmosphere. During final annealing, the cold rolled sheet recrystallizes to an average grain size of about 10 to 30 .mu.m. Final stress relief annealing can be carried out in the B2 phase temperature range.

  3. Energetic electron spectra in Saturn's plasma sheet

    Science.gov (United States)

    Carbary, J. F.; Paranicas, C.; Mitchell, D. G.; Krimigis, S. M.; Krupp, N.

    2011-07-01

    The differential spectra of energetic electrons (27-400 keV) in Saturn's plasma sheet can be characterized by power law or kappa distributions. Using all available fluxes from 2005 to 2010, fits to these distributions reveal a striking and consistent pattern of radial dependence in Saturn's plasma sheet (∣z∣ constant throughout the Cassini mission. Inward of about 10 RS, the presence of the electron radiation belts and losses of lower-energy electrons to the gas and grain environment give rise to the very hard spectra in the inner magnetosphere, while the hard spectra in the outer magnetosphere may derive from auroral acceleration at high latitudes. The gradual softening of the spectra from 20 to 10 RS is explained by inward radial diffusion.

  4. Current sheets with inhomogeneous plasma temperature: Effects of polarization electric field and 2D solutions

    Energy Technology Data Exchange (ETDEWEB)

    Catapano, F., E-mail: menacata3@gmail.com; Zimbardo, G. [Dipartimento di Fisica, Università della Calabria, Rende, Cosenza (Italy); Artemyev, A. V., E-mail: ante0226@gmail.com; Vasko, I. Y. [Space Research Institute, RAS, Moscow (Russian Federation)

    2015-09-15

    We develop current sheet models which allow to regulate the level of plasma temperature and density inhomogeneities across the sheet. These models generalize the classical Harris model via including two current-carrying plasma populations with different temperature and the background plasma not contributing to the current density. The parameters of these plasma populations allow regulating contributions of plasma density and temperature to the pressure balance. A brief comparison with spacecraft observations demonstrates the model applicability for describing the Earth magnetotail current sheet. We also develop a two dimensional (2D) generalization of the proposed model. The interesting effect found for 2D models is the nonmonotonous profile (along the current sheet) of the magnetic field component perpendicular to the current sheet. Possible applications of the model are discussed.

  5. Plasma Relaxation Dynamics Moderated by Current Sheets

    Science.gov (United States)

    Dewar, Robert; Bhattacharjee, Amitava; Yoshida, Zensho

    2014-10-01

    Ideal magnetohydrodynamics (IMHD) is strongly constrained by an infinite number of microscopic constraints expressing mass, entropy and magnetic flux conservation in each infinitesimal fluid element, the latter preventing magnetic reconnection. By contrast, in the Taylor-relaxed equilibrium model all these constraints are relaxed save for global magnetic flux and helicity. A Lagrangian is presented that leads to a new variational formulation of magnetized fluid dynamics, relaxed MHD (RxMHD), all static solutions of which are Taylor equilibrium states. By postulating that some long-lived macroscopic current sheets can act as barriers to relaxation, separating the plasma into multiple relaxation regions, a further generalization, multi-relaxed MHD (MRxMHD), is developed. These concepts are illustrated using a simple two-region slab model similar to that proposed by Hahm and Kulsrud--the formation of an initial shielding current sheet after perturbation by boundary rippling is calculated using MRxMHD and the final island state, after the current sheet has relaxed through a reconnection sequence, is calculated using RxMHD. Australian Research Council Grant DP110102881.

  6. High-beta plasma blobs in the morningside plasma sheet

    Directory of Open Access Journals (Sweden)

    G. Haerendel

    Full Text Available Equator-S frequently encountered, i.e. on 30% of the orbits between 1 March and 17 April 1998, strong variations of the magnetic field strength of typically 5–15-min duration outside about 9RE during the late-night/early-morning hours. Very high-plasma beta values were found, varying between 1 and 10 or more. Close conjunctions between Equator-S and Geotail revealed the spatial structure of these "plasma blobs" and their lifetime. They are typically 5–10° wide in longitude and have an antisymmetric plasma or magnetic pressure distribution with respect to the equator, while being altogether low-latitude phenomena 
    (≤ 15°. They drift slowly sunward, exchange plasma across the equator and have a lifetime of at least 15–30 min. While their spatial structure may be due to some sort of mirror instability, little is known about the origin of the high-beta plasma. It is speculated that the morningside boundary layer somewhat further tailward may be the source of this plasma. This would be consistent with the preference of the plasma blobs to occur during quiet conditions, although they are also found during substorm periods. The relation to auroral phenomena in the morningside oval is uncertain. The energy deposition may be mostly too weak to generate a visible signature. However, patchy aurora remains a candidate for more disturbed periods.

    Key words. Magnetospheric physics (plasma convection; plasma sheet; plasma waves and instabilities

  7. The Dynamical Generation of Current Sheets in Astrophysical Plasma Turbulence

    CERN Document Server

    Howes, Gregory G

    2016-01-01

    Turbulence profoundly affects particle transport and plasma heating in many astrophysical plasma environments, from galaxy clusters to the solar corona and solar wind to Earth's magnetosphere. Both fluid and kinetic simulations of plasma turbulence ubiquitously generate coherent structures, in the form of current sheets, at small scales, and the locations of these current sheets appear to be associated with enhanced rates of dissipation of the turbulent energy. Therefore, illuminating the origin and nature of these current sheets is critical to identifying the dominant physical mechanisms of dissipation, a primary aim at the forefront of plasma turbulence research. Here we present evidence from nonlinear gyrokinetic simulations that strong nonlinear interactions between counterpropagating Alfven waves, or strong Alfven wave collisions, are a natural mechanism for the generation of current sheets in plasma turbulence. Furthermore, we conceptually explain this current sheet development in terms of the nonlinear...

  8. New aspects of plasma sheet dynamics - MHD and kinetic theory

    Directory of Open Access Journals (Sweden)

    H. Wiechen

    Full Text Available Magnetic reconnection is a process of fundamental importance for the dynamics of the Earth's plasma sheet. In this context, the development of thin current sheets in the near-Earth plasma sheet is a topic of special interest because they could be a possible cause of microscopic fluctuations acting as collective non-idealness from a macroscopic point of view. Simulations of the near-Earth plasma sheet including boundary perturbations due to localized inflow through the northern (or southern plasma sheet boundary show developing thin current sheets in the near-Earth plasma sheet about 810 RE tailwards of the Earth. This location is largely independent from the localization of the perturbation. The second part of the paper deals with the problem of the macroscopic non-ideal consequences of microscopic fluctuations. A new model is presented that allows the quantitative calculation of macroscopic non-idealness without considering details of microscopic instabilities or turbulence. This model is only based on the assumption of a strongly fluctuating, mixing dynamics on microscopic scales in phase space. The result of this approach is an expression for anomalous non-idealness formally similar to the Krook resistivity but now describing the macroscopic consequences of collective microscopic fluctuations, not of collisions.

    Key words. Magnetospheric physics (plasma sheet · Space plasma physics (kinetic and MHD theory; magnetic reconnection

  9. Magnetic turbulence in the plasma sheet

    CERN Document Server

    Vörös, Z; Nakamura, R; Runov, A; Zhang, T L; Eichelberger, H U; Treumann, R A; Georgescu, E; Balogh, A; Klecker, B; R`eme, H

    2004-01-01

    Small-scale magnetic turbulence observed by the Cluster spacecraft in the plasma sheet is investigated by means of a wavelet estimator suitable for detecting distinct scaling characteristics even in noisy measurements. The spectral estimators used for this purpose are affected by a frequency dependent bias. The variances of the wavelet coefficients, however, match the power-law shaped spectra, which makes the wavelet estimator essentially unbiased. These scaling characteristics of the magnetic field data appear to be essentially non-steady and intermittent. The scaling properties of bursty bulk flow (BBF) and non-BBF associated magnetic fluctuations are analysed with the aim of understanding processes of energy transfer between scales. Small-scale ($\\sim 0.08-0.3$ s) magnetic fluctuations having the same scaling index $\\alpha \\sim 2.6$ as the large-scale ($\\sim 0.7-5$ s) magnetic fluctuations occur during BBF-associated periods. During non-BBF associated periods the energy transfer to small scales is absent, ...

  10. Gyrophase bunched ions in the plasma sheet

    Science.gov (United States)

    Wang, Zhiqiang; Zhai, Hao; Gao, Zhuxiu; Huang, Chaoyan

    2017-01-01

    Gyrophase bunched ions were first detected in the upstream region of the Earth's bow shock in the early 1980s which is formed by the microphysical process associated with reflected solar wind ions at the bow shock. Inside the magnetosphere, the results of computer simulations demonstrated that nonlinear wave-particle interaction can also result in the gyrophase bunching of particles. However, to date direct observations barely exist regarding this issue occurred inside the magnetosphere. In this paper, we report for the first time an event of gyrophase bunched ions observed in the near-Earth plasma sheet. The nongyrotropic distributions of ions were closely accompanied with the electromagnetic waves at the oxygen cyclotron frequency. The phase of bunched ions and the phase of waves mainly have very narrow phase differences (helicity with respect to the propagation direction, which agrees with the characteristic of electromagnetic ion cyclotron waves. The observation of O+ ions composition suggests that the oxygen band waves are excited due to the enhancements of the O+ ion density. This study suggests that the gyrophase bunching is a significant nonlinear effect that exists not only in the bow shock but also in the inner magnetosphere.

  11. Thickness of Heliospheric Current and Plasma Sheets: Dependence on Distance

    Science.gov (United States)

    Zhou, X.; Smith, E. J.; Winterhalter, D.; McComas, D. J.; Skoug, R. M.; Goldstein, B. E.; Smith, C. W.

    2005-05-01

    Heliospheric current sheets (HCS) are well defined structures that separate the interplanetary magnetic fields with inverse polarities. Surrounded by heliospheric plasma sheets (HPS), the current sheets stretch throughout the heliosphere. Interesting questions that still remain unanswered include how the thickness of these structures will change along the distance? And what determines the thickness of these structures? To answer these fundamental questions, we have carried out a study of the HCS and HPS using recent Ulysses data near 5 AU. When the results were compared with earlier studies at 1 AU using ISEE-3 data, they were surprising and unexplained. Although the plasma sheet grew thicker, the embedded current sheet grew thinner! Using data under the same (or very similar) circumstances, we have extended the analysis in two ways. First, the same current-plasma sheets studied at 5 AU have been identified at 1 AU using ACE data. Second, data obtained while Ulysses was en-route to Jupiter near 3 AU have been analyzed. This three-point investigation reveals the thickness variation along the distance and enables the examination of the controller of this variation.

  12. Magnetic configuration of the distant plasma sheet - ISEE 3 observations

    Science.gov (United States)

    Slavin, J. A.; Smith, E. J.; Daly, P. W.; Sanderson, T. R.; Wenzel, K.-P.; Lepping, R. P.

    1987-01-01

    The influence of the IMF orientation and magnitude and substorm activity on the magnetic configuration of the central plasma sheet at 20-240 earth radii down the geomagnetic tail is investigated on the basis of ISEE-3 data. The results are presented graphically, and high-speed antisolar bulk flows threaded by southward magnetic fields are shown to be present in the distant plasma sheet after periods of substorm activity and southward IMF Bz. The effective dayside reconnection efficiency is estimated as 25 + or - 4 percent, in good agreement with theoretical models.

  13. Physics and Dynamics of Current Sheets in Pulsed Plasma Thrusters

    Science.gov (United States)

    2007-11-02

    pulsed plasma thruster. A simple experiment would involve measuring the impulse bit of a coaxial gas-fed pulsed plasma thruster operated in both positive...Princeton, NJ, 2002. [2] J. Marshal. Performance of a hydromagnetic plasma gun . The Physics of Fluids, 3(1):134–135, January-February 1960. [3] R.G. Jahn...Jahn and K.E. Clark. A large dielecteic vacuum facility. AIAA Jour- nal, 1966. [16] L.C. Burkhardt and R.H. Lovberg. Current sheet in a coaxial plasma

  14. Plasma-Jet Forming of Sheet Metal Shapes

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Plasma-jet forming is a newly proposed flexible sheet metal forming process. A non-transferred arc plasma torch is used as a controllable heat source to produce internal stress in sheet metals, causing plastic deformation without the necessity of hard tooling. This method has potential for rapid prototyping of sheet metal parts by reducing development costs and lead times. A robotic system has been used to perform simple linear bends in several different alloys. In order to develop a controllable process and to improve the forming accuracy, the effects of various process parameters on the obtained shape changes and on the resulting structure and properties have been studied. The overall goal is to understand the roles of the forming parameters and their inter-relationship in optimizing the forming procedure-a high forming speed without damage to the material structure or properties.

  15. Geomagnetic activity effects on plasma sheet energy conversion

    Directory of Open Access Journals (Sweden)

    M. Hamrin

    2010-10-01

    Full Text Available In this article we use three years (2001, 2002, and 2004 of Cluster plasma sheet data to investigate what happens to localized energy conversion regions (ECRs in the plasma sheet during times of high magnetospheric activity. By examining variations in the power density, E·J, where E is the electric field and J is the current density obtained by Cluster, we have studied the influence on Concentrated Load Regions (CLRs and Concentrated Generator Regions (CGRs from variations in the geomagnetic disturbance level as expressed by the Kp, the AE, and the Dst indices. We find that the ECR occurrence frequency increases during higher magnetospheric activities, and that the ECRs become stronger. This is true both for CLRs and for CGRs, and the localized energy conversion therefore concerns energy conversion in both directions between the particles and the fields in the plasma sheet. A higher geomagnetic activity hence increases the general level of energy conversion in the plasma sheet. Moreover, we have shown that CLRs live longer during magnetically disturbed times, hence converting more electromagnetic energy. The CGR lifetime, on the other hand, seems to be unaffected by the geomagnetic activity level. The evidence for increased energy conversion during geomagnetically disturbed times is most clear for Kp and for AE, but there are also some indications that energy conversion increases during large negative Dst. This is consistent with the plasma sheet magnetically mapping to the auroral zone, and therefore being more tightly coupled to auroral activities and variations in the AE and Kp indices, than to variations in the ring current region as described by the Dst index.

  16. IMF dependence of energetic oxygen and hydrogen ion distributions in the near-Earth plasma sheet

    Science.gov (United States)

    Luo, Hao; Kronberg, Elena; Nykyri, Katariina; Daly, Patrick; Chen, Gengxiong; Du, Aimin; Ge, Yasong

    2017-04-01

    Energetic ion distributions in the near-Earth plasma sheet can provide important information for understanding the entry of ions into the magnetosphere, and their transportation, acceleration, and losses in the near-Earth region. In this study, 11 years of energetic proton and oxygen observations (> 100 keV) from Cluster/RAPID were used to statistically study the energetic ion distributions in the near-Earth region. The dawn-dusk asymmetries of the distributions in three different regions (dayside magnetosphere, near-Earth nightside plasma sheet, and tail plasma sheet) are examined in northern and southern hemispheres. The results show that the energetic ion distributions are influenced by the dawn-dusk IMF direction. The enhancement of intensity largely correlates with the location of the magnetic reconnection at the magnetopause and the consequent formation of a diamagnetic cavity in the same quadrant of the magnetosphere. The results imply that substorm-related processes in the magnetotail are not the only source of energetic ions in the dayside and the near-Earth plasma sheet. We propose that large-scale cusp diamagnetic cavities can be an additional source and can thus significantly affect the energetic ion population in the magnetosphere. We also believe that the influence of the dawn-dusk IMF direction should not be neglected in models of the particle population in the magnetosphere.

  17. Ion Beams in the Plasma Sheet Boundary Layer

    Science.gov (United States)

    Birn, J.; Hesse, M.; Runov, A.; Zhou, X.

    2015-12-01

    We explore characteristics of energetic particles in the plasma sheet boundary layer associated with dipolarization events, based on simulations and observations. The simulations use the electromagnetic fields of an MHD simulation of magnetotail reconnection and flow bursts as basis for test particle tracing. They are complemented by self-consistent fully electrodynamic particle-in-cell (PIC) simulations. The test particle simulations confirm that crescent shaped earthward flowing ion velocity distributions with strong perpendicular anisotropy can be generated as a consequence of near tail reconnection, associated with earthward flows and propagating magnetic field dipolarization fronts. Both PIC and test particle simulations show that the ion distribution in the outflow region close to the reconnection site also consist of a beam superposed on an undisturbed population; this beam, however, does not show strong perpendicular anisotropy. This suggests that the crescent shape is created by quasi-adiabatic deformation from ion motion along the magnetic field toward higher field strength. The simulation results compare favorably with ``Time History of Events and Macroscale Interactions during Substorms" (THEMIS) observations.

  18. Comparison of plasma sheet ion composition with the IMF and solar wind plasma

    Science.gov (United States)

    Lennartsson, W.

    Plasma sheet energetic ion data (0.1- to 16 keV/e) obtained by the Plasma Composition Experiment on ISEE-1 between 10 and 23 earth radii are compared with concurrent IMF and solar wind plasma data. The densities of H(+) and He(++) ions in the plasma sheet are found to be the highest, and the most nearly proportional to the solar wind density, when the IMF B(z) is not northward. The density of terrestrial O(+) ions increases strongly with increasing magnitude of the IMF, in apparent agreement with the notion that the IMF plays a fundamental role in the electric coupling between the solar wind and the ionosphere.

  19. On the nature of the plasma sheet boundary layer

    Energy Technology Data Exchange (ETDEWEB)

    Hones, E.W. Jr. (Mission Research Corp., Los Alamos, NM (USA) Los Alamos National Lab., NM (USA))

    1990-01-01

    The regions of the plasma sheet adjacent to the north and south lobes of the magnetotail have been described by many experimenters as locations of beams of energetic ions and fast-moving plasma directed primarily earthward and tailward along magnetic field lines. Measurements taken as satellites passed through one or the other of these boundary layers have frequently revealed near-earth mirroring of ions and a vertical segregation of velocities of both earthward-moving and mirroring ions with the fastest ions being found nearest the lobe-plasma sheet interface. These are features expected for particles from a distant tail source {bar E} {times} {bar B} drifting in a dawn-to-dusk electric field and are consistent with the source being a magnetic reconnection region. The plasma sheet boundary layers are thus understood as separatrix layers, bounded at their lobeward surfaces by the separatrices from the distant neutral line. This paper will review the observations that support this interpretation. 10 refs., 7 figs.

  20. 3-D Magnetospheric Field and Plasma Containing Thin Current Sheets

    Science.gov (United States)

    Zaharia, S.; Cheng, C. Z.; Maezawa, K.; Wing, S.

    2002-05-01

    In this study we present fully-3D self-consistent solutions of the magnetosphere by using observation-based plasma pressure distributions and computational boundary conditions based on the T96 magnetospheric field model. The pressure profiles we use are either taken directly from observations (GEOTAIL pressure data in the plasma sheet and DMSP ionospheric pressure) or empirical (Spence-Kivelson formula for pressure on the midnight equatorial line). The 3-D solutions involve solving 2 coupled elliptic equations in a flux coordinate systems, with the magnetic field expressed by two Euler potentials and using appropriate boundary conditions for both the closed- and open-field regions derived from the empirical field model. We look into how the self-consistent magnetic field and current structures change under different external conditions, and we discuss the appearance of thin cross-tail current sheets during disturbed magnetospheric times.

  1. Singular Sheet Etching of Graphene with Oxygen Plasma

    Institute of Scientific and Technical Information of China (English)

    Haider Al-Mumen; Fubo Rao; Wen Li; Lixin Dong

    2014-01-01

    This paper reports a simple and controllable post-synthesis method for engineering the number of graphene layers based on oxygen plasma etching. Singular sheet etching (SSE) of graphene was achieved with the optimum process duration of 38 seconds. As a demonstration of this SSE process, monolayer graphene films were produced from bilayer graphenes. Experimental investigations verified that the oxygen plasma etching removes a single layer graphene sheet in an anisotropic fashion rather than anisotropic mode. In addition, etching via the oxygen plasma at the ground electrodes introduced fewer defects to the bottom graphene layer compared with the conventional oxygen reactive ion etching using the powered electrodes. Such defects can further be reduced with an effective annealing treatment in an argon environment at 900-1000◦C. These results demonstrate that our developed SSE method has enabled a microelectronics manufacturing compatible way for single sheet precision subtraction of graphene layers and a potential technique for producing large size graphenes with high yield from multilayer graphite materials.

  2. Analysis of radiation performances of plasma sheet antenna

    Science.gov (United States)

    Yin, Bo; Zhang, Zu-Fan; Wang, Ping

    2015-12-01

    A novel concept of plasma sheet antennas is presented in this paper, and the radiation performances of plasma sheet antennas are investigated in detail. Firstly, a model of planar plasma antenna (PPA) fed by a microstrip line is developed, and its reflection coefficient is computed by the JE convolution finite-difference time-domain method and compared with that of the metallic patch antenna. It is found that the design of PPA can learn from the theory of the metallic patch antenna, and the impedance matching and reconstruction of resonant frequency can be expediently realized by adjusting the parameters of plasma. Then the PPA is mounted on a metallic cylindrical surface, and the reflection coefficient of the conformal plasma antenna (CPA) is also computed. At the same time, the influence of conformal cylinder radius on the reflection coefficient is also analyzed. Finally, the radiation pattern of a CPA is given, the results show that the pattern agrees well with the one of PPA in the main radiation direction, but its side lobe level has deteriorated significantly.

  3. Thin current sheets caused by plasma flow gradients in space plasma

    Science.gov (United States)

    Nickeler, D.; Wiegelmann, T.

    2011-12-01

    To understand complex space plasma systems like the solar wind-magnetosphere coupling, we need to have a good knowledge of the slowly evolving equilibrium state. The slow change of external constraints on the system (for example boundary conditions or other external parameters) lead in many cases to the formation of current sheets. These current sheets can trigger micro-instabilities, which cause resistivity on fluid scales. Consequently resistive instabilities like magnetic reconnection can occur and the systems evolves dynamically. Therefore such a picture of quasi-magneto-hydro-static changes can explain the quasy-static phase of many space plasma before an eruption occurs. Within this work we extend the theory by the inclusion of a nonlinear stationary plasma flows. Our analysis shows that stationary plasma flows with strong flow gradients (for example the solar wind magnetosphere coupling) can be responsible for the existence or generation of current sheets.

  4. Survey of Galileo Plasma Observations in Jupiter's Plasma Sheet

    Science.gov (United States)

    Bagenal, Fran; Wilson, Robert J.; Siler, Scott; Paterson, William R.; Kurth, William S.

    2016-01-01

    The plasma science (PLS) Instrument on the Galileo spacecraft (orbiting Jupiter from December 1995 to September 2003) measured properties of the ions that were trapped in the magnetic field. The PLS data provide a survey of the plasma properties between approx. 5 and 30 Jupiter radii [R(sub J)] in the equatorial region. We present plasma properties derived via two analysis methods: numerical moments and forward modeling. We find that the density decreases with radial distance by nearly 5 orders of magnitude from approx. 2 to 3000 cm(exp.-3) at 6R(sub j) to approx. 0.05cm(sub -3) at 30 R(sub j). The density profile did not show major changes from orbit to orbit, suggesting that the plasma production and transport remained constant within about a factor of 2. The radial profile of ion temperature increased with distance which implied that contrary to the concept of adiabatic cooling on expansion, the plasma heats up as it expands out from Io's orbit (where TI is approx.60-80 eV) at approx. 6R(sub j) to a few keV at 30R(sub j).There does not seem to be a long-term, systematic variation in ion temperature with either local time or longitude. This latter finding differs from earlier analysis of Galileo PLS data from a selection of orbits. Further examination of all data from all Galileo orbits suggests that System Ill variations are transitory on timescales of weeks, consistent with the modeling of Cassini Ultraviolet Imaging Spectrograph observations. The plasma flow is dominated by azimuthal flow that is between 80% and 100% of corotation out to 25 R(sub j).

  5. Thin current sheets in collisionless plasma: Equilibrium structure, plasma instabilities, and particle acceleration

    Energy Technology Data Exchange (ETDEWEB)

    Zelenyi, L. M.; Malova, H. V.; Artemyev, A. V.; Popov, V. Yu.; Petrukovich, A. A. [Russian Academy of Sciences, Space Research Institute (Russian Federation)

    2011-02-15

    The review is devoted to plasma structures with an extremely small transverse size, namely, thin current sheets that have been discovered and investigated by spacecraft observations in the Earth's magnetotail in the last few decades. The formation of current sheets is attributed to complicated dynamic processes occurring in a collisionless space plasma during geomagnetic perturbations and near the magnetic reconnection regions. The models that describe thin current structures in the Earth's magnetotail are reviewed. They are based on the assumption of the quasi-adiabatic ion dynamics in a relatively weak magnetic field of the magnetotail neutral sheet, where the ions can become unmagnetized. It is shown that the ion distribution can be represented as a function of the integrals of particle motion-the total energy and quasi-adiabatic invariant. Various modifications of the initial equilibrium are considered that are obtained with allowance for the currents of magnetized electrons, the contribution of oxygen ions, the asymmetry of plasma sources, and the effects related to the non-Maxwellian particle distributions. The theoretical results are compared with the observational data from the Cluster spacecraft mission. Various plasma instabilities developing in thin current sheets are investigated. The evolution of the tearing mode is analyzed, and the parameter range in which the mode can grow are determined. The paradox of complete stabilization of the tearing mode in current sheets with a nonzero normal magnetic field component is thereby resolved based on the quasi-adiabatic model. It is shown that, over a wide range of current sheet parameters and the propagation directions of large-scale unstable waves, various modified drift instabilities-kink and sausage modes-can develop in the system. Based on the concept of a turbulent electromagnetic field excited as a result of the development and saturation of unstable waves, a mechanism for charged particle

  6. The statistical studies of the inner boundary of plasma sheet

    Directory of Open Access Journals (Sweden)

    J. B. Cao

    2011-02-01

    Full Text Available The penetration of plasma sheet ions into the inner magnetosphere is very important to the inner magnetospheric dynamics since plasma sheet ions are one of the major particle sources of ring current during storm times. However, the direct observations of the inner boundary of the plasma sheet are fairly rare due to the limited number of satellites in near equatorial orbits outside 6.6 RE. In this paper, we used the ion data recorded by TC-1 from 2004 to 2006 to study the distribution of inner boundary of ion plasma sheet (IBIPS and for the first time show the observational distribution of IBIPS in the equatorial plane. The IBIPS has a dawn-dusk asymmetry, being farthest to the Earth in the 06:00 08:00 LT bin and closest to the Earth in the 18:00–20:00 LT bin. Besides, the IBIPS has also a day-night asymmetry, which may be due to the fact that the ions on the dayside are exposed more time to loss mechanisms on their drift paths. The radial distance of IBIPS decrease generally with the increase of Kp index. The mean radial distance of IBIPS is basically larger than 6.6 RE during quiet times and smaller than 6.6 RE during active times. When the strength of convection electric field increases, the inward shift of IBIPS is most significant on the night side (22:00–02:00 LT. For Kp ≤ 0+, only 16% of IBIPSs penetrate inside the geosynchronous orbit. For 2 ≤ Kp < 3+, however, 70% of IBIPSs penetrate inside the geosynchronous orbit. The IBIPS has weak correlations with the AE and Dst indexes. The average correlation coefficient between Ri and Kp is −0.58 while the correlation coefficient between Ri and AE/Dst is only −0.29/0.17. The correlation coefficients are local time dependent. Particularly, Ri and Kp are highly correlated (r=−0.72 in the night sector, meaning that the radial distance of IBIPS

  7. Effects of auroral potential drops on plasma sheet dynamics

    Science.gov (United States)

    Xi, Sheng; Lotko, William; Zhang, Binzheng; Wiltberger, Michael; Lyon, John

    2016-11-01

    The reaction of the magnetosphere-ionosphere system to dynamic auroral potential drops is investigated using the Lyon-Fedder-Mobarry global model including, for the first time in a global simulation, the dissipative load of field-aligned potential drops in the low-altitude boundary condition. This extra load reduces the field-aligned current (j||) supplied by nightside reconnection dynamos. The system adapts by forcing the nightside X line closer to Earth, with a corresponding reduction in current lensing (j||/B = constant) at the ionosphere and additional contraction of the plasma sheet during substorm recovery and steady magnetospheric convection. For steady and moderate solar wind driving and with constant ionospheric conductance, the cross polar cap potential and hemispheric field-aligned current are lower by approximately the ratio of the peak field-aligned potential drop to the cross polar cap potential (10-15%) when potential drops are included. Hemispheric ionospheric Joule dissipation is less by 8%, while the area-integrated, average work done on the fluid by the reconnecting magnetotail field increases by 50% within |y| < 8 RE. Effects on the nightside plasma sheet include (1) an average X line 4 RE closer to Earth; (2) a 12% higher mean reconnection rate; and (3) dawn-dusk asymmetry in reconnection with a 17% higher rate in the premidnight sector.

  8. Cluster multi-point observations of the magnetotail plasma sheet

    Science.gov (United States)

    Henderson, Paul David

    This thesis presents observations of the terrestrial magnetotail plasma sheet made by the European Space Agency Cluster mission. The Cluster mission is composed of four identical spacecraft, the first such multi-spacecraft mission, and enables, for the first time, the disambiguation of time versus space phenomena. Using the data from 2003, when the spacecraft were at their smallest average separation to date, many small-scale processes, both microphysical and macrophysical, are investigated. In the first study presented, two small flux ropes, a possible signature of multiple X-line reconnection, are investigated. By the development and utilisation of various multi-spacecraft methods, the currents and magnetic forces internal and external to the flux ropes, as well as the internal structure of the flux ropes, are investigated. In addition, a theory of their early evolution is suggested. In the second study presented, various terms of the generalised Ohm's law for a plasma are determined, including, for the first time, the divergence of the full electron pressure tensor, during the passage past the spacecraft of an active reconnection X-line. It is found that the electric field contribution from the divergence of the electron pressure tensor is anti-correlated with the contribution from the Hall term in the direction normal to the neutral sheet. In addition, further signatures of reconnection are quantified, such as parallel electric field generation and Hall quadrupolar magnetic field and current systems. In the final study presented, the anti-correlation between the divergence of the electron pressure tensor and Hall terms is investigated further. It is found that the anti-correlation is general, appearing in the direction normal to the neutral sheet because of a cross tail current. In a simple magnetohydrostatic treatment, a force balance argument leads to the conclusion that the gradient of the anti-correlation is a function of the ratio of the electron to ion

  9. Casimir effects for a flat plasma sheet: I. Energies

    Energy Technology Data Exchange (ETDEWEB)

    Barton, G [Department of Physics and Astronomy, University of Sussex, Brighton BN1 9QH (United Kingdom)

    2005-04-01

    We study a fluid model of an infinitesimally thin plasma sheet occupying the xy plane, loosely imitating a single base plane from graphite. In terms of the fluid charge e/a{sup 2} and mass m/a{sup 2} per unit area, the crucial parameters are q nsce 2{pi}e{sup 2}/mc{sup 2}a{sup 2}, a Debye-type cutoff K{identical_to}{radical}(4{pi})/a on surface-parallel normal-mode wavenumbers k, and X nsce K/q. The cohesive energy {beta} per unit area is determined from the zero-point energies of the exact normal modes of the plasma coupled to the Maxwell field, namely TE and TM photon modes, plus bound modes decaying exponentially with vertical bar zvertical bar. Odd-parity modes (with E{sub x,y}(z = 0) = 0) are unaffected by the sheet except for their overall phases, and are irrelevant to {beta}, although the following paper shows that they are essential to the fields (e.g. to their vacuum expectation values), and to the stresses on the sheet. Realistically one has X >> 1, the result {beta} {approx} {Dirac_h}cq{sup 1/2}K{sup 5/2} is nonrelativistic, and it comes from the surface modes. By contrast, X << 1 (nearing the limit of perfect reflection) would entail {beta} {approx} -{Dirac_h}cqK{sup 2}log(1/X): contrary to folklore, the surface energy of perfect reflectors is divergent rather than zero. An appendix spells out the relation, for given k, between bound modes and photon phase-shifts. It is very different from Levinson's theorem for 1D potential theory: cursory analogies between TM and potential scattering are apt to mislead.

  10. Thin current sheets caused by plasma flow gradients in space and astrophysical plasma

    Directory of Open Access Journals (Sweden)

    D. H. Nickeler

    2010-08-01

    Full Text Available Strong gradients in plasma flows play a major role in space and astrophysical plasmas. A typical situation is that a static plasma equilibrium is surrounded by a plasma flow, which can lead to strong plasma flow gradients at the separatrices between field lines with different magnetic topologies, e.g., planetary magnetospheres, helmet streamers in the solar corona, or at the boundary between the heliosphere and interstellar medium. Within this work we make a first step to understand the influence of these flows towards the occurrence of current sheets in a stationary state situation. We concentrate here on incompressible plasma flows and 2-D equilibria, which allow us to find analytic solutions of the stationary magnetohydrodynamics equations (SMHD. First we solve the magnetohydrostatic (MHS equations with the help of a Grad-Shafranov equation and then we transform these static equilibria into a stationary state with plasma flow. We are in particular interested to study SMHD-equilibria with strong plasma flow gradients perpendicular to separatrices. We find that induced thin current sheets occur naturally in such situations. The strength of the induced currents depend on the Alfvén Mach number and its gradient, and on the magnetic field.

  11. Central Plasma Sheet Ion Properties as Inferred from Ionospheric Observations

    Science.gov (United States)

    Wing, Simon; Newell, Patrick T.

    1998-01-01

    A method of inferring central plasma sheet (CPS) temperature, density, and pressure from ionospheric observations is developed. The advantage of this method over in situ measurements is that the CPS can be studied in its entirely, rather than only in fragments. As a result, for the first time, comprehensive two-dimensional equatorial maps of CPS pressure, density, and temperature within the isotropic plasma sheet are produced. These particle properties are calculated from data taken by the Special Sensor for Precipitating Particles, version 4 (SSJ4) particle instruments onboard DMSP F8, F9, F10, and F11 satellites during the entire year of 1992. Ion spectra occurring in conjunction with electron acceleration events are specifically excluded. Because of the variability of magnetotail stretching, the mapping to the plasma sheet is done using a modified Tsyganenko [1989] magnetic field model (T89) adjusted to agree with the actual magnetotail stretch at observation time. The latter is inferred with a high degree of accuracy (correlation coefficient -0.9) from the latitude of the DMSP b2i boundary (equivalent to the ion isotropy boundary). The results show that temperature, pressure, and density all exhibit dawn-dusk asymmetries unresolved with previous measurements. The ion temperature peaks near the midnight meridian. This peak, which has been associated with bursty bulk flow events, widens in the Y direction with increased activity. The temperature is higher at dusk than at dawn, and this asymmetry increases with decreasing distance from the Earth. In contrast, the density is higher at dawn than at dusk, and there appears to be a density enhancement in the low-latitude boundary layer regions which increases with decreasing magnetic activity. In the near-Earth regions, the pressure is higher at dusk than at dawn, but this asymmetry weakens with increasing distance from the Earth and may even reverse so that at distances X less than approx. 10 to -12 R(sub E

  12. Experimental investigation of a 1 kA/cm² sheet beam plasma cathode electron gun.

    Science.gov (United States)

    Kumar, Niraj; Pal, Udit Narayan; Pal, Dharmendra Kumar; Prajesh, Rahul; Prakash, Ram

    2015-01-01

    In this paper, a cold cathode based sheet-beam plasma cathode electron gun is reported with achieved sheet-beam current density ∼1 kA/cm(2) from pseudospark based argon plasma for pulse length of ∼200 ns in a single shot experiment. For the qualitative assessment of the sheet-beam, an arrangement of three isolated metallic-sheets is proposed. The actual shape and size of the sheet-electron-beam are obtained through a non-conventional method by proposing a dielectric charging technique and scanning electron microscope based imaging. As distinct from the earlier developed sheet beam sources, the generated sheet-beam has been propagated more than 190 mm distance in a drift space region maintaining sheet structure without assistance of any external magnetic field.

  13. Spatial variation of eddy-diffusion coefficients in the turbulent plasma sheet during substorms

    Directory of Open Access Journals (Sweden)

    M. Stepanova

    2009-04-01

    Full Text Available Study of the plasma turbulence in the central plasma sheet was performed using the Interball-Tail satellite data. Fluctuations of the plasma bulk velocity in the plasma sheet were deduced from the measurements taken by the Corall instrument for different levels of geomagnetic activity and different locations inside the plasma sheet. The events that satisfied the following criteria were selected for analysis: number density 0.1–10 cm−3, ion temperature T≥0.3 keV, and average bulk velocity ≤100 km/s. It was found that the plasma sheet flow generally appears to be strongly turbulent, i.e. is dominated by fluctuations that are unpredictable. Corresponding eddy-diffusion coefficients in Y- and Z-direction in the GSM coordinate system were derived using the autocorrelation time and rms velocity. Statistical studies of variation of the eddy-diffusion coefficients with the location inside the plasma sheet showed a significant increase in these coefficients in the tailward direction. During substorms this dependence shows strong increase of eddy-diffusion in the central part of the plasma sheet at the distances of 10–30 Earth's radii. This effect is much stronger for Y-components of the eddy-diffusion coefficient, which could be related to the geometry of the plasma sheet, allowing more room for development of eddies in this direction.

  14. A computational model for He{sup +} ions in a magnetized sheet plasma: comparative analysis between model and experimental data

    Energy Technology Data Exchange (ETDEWEB)

    Blantocas, Gene Q. [West Visayas State Univ., Lapaz, Iloilo City (Philippines); Ramos, Henry J. [Univ. of the Phillippines, College of Science, National Inst. of Physics, Deliman Quezon City (Philippines); Wada, Motoi [Doshisha Univ., Dept. of Engineering, Kyoto (Japan)

    2003-07-01

    An E x B probe was used to extract He{sup +} ions from a magnetized steady sheet plasma. Plasma parameters T{sub e}, n{sub e} and extracted He{sup +} ion current were analyzed vis-a-vis a modified Saha population density equation of the collisional-radiative model. Numerical calculations show that at low discharge currents and in the hot electron region of the sheet plasma, relative densities of He{sup +} ions show some degree of correlation with ion current profiles established experimentally using the E x B probe. Both experimental and computational results indicate a division of the plasma into two distinct regions each with different formation mechanisms of He{sup +} ions. (author)

  15. A statistical study on the correlations between plasma sheet and solar wind based on DSP explorations

    Directory of Open Access Journals (Sweden)

    G. Q. Yan

    2005-11-01

    Full Text Available By using the data of two spacecraft, TC-1 and ACE (Advanced Composition Explorer, a statistical study on the correlations between plasma sheet and solar wind has been carried out. The results obtained show that the plasma sheet at geocentric distances of about 9~13.4 Re has an apparent driving relationship with the solar wind. It is found that (1 there is a positive correlation between the duskward component of the interplanetary magnetic field (IMF and the duskward component of the geomagnetic field in the plasma sheet, with a proportionality constant of about 1.09. It indicates that the duskward component of the IMF can effectively penetrate into the near-Earth plasma sheet, and can be amplified by sunward convection in the corresponding region at geocentric distances of about 9~13.4 Re; (2 the increase in the density or the dynamic pressure of the solar wind will generally lead to the increase in the density of the plasma sheet; (3 the ion thermal pressure in the near-Earth plasma sheet is significantly controlled by the dynamic pressure of solar wind; (4 under the northward IMF condition, the ion temperature and ion thermal pressure in the plasma sheet decrease as the solar wind speed increases. This feature indicates that plasmas in the near-Earth plasma sheet can come from the magnetosheath through the LLBL. Northward IMF is one important condition for the transport of the cold plasmas of the magnetosheath into the plasma sheet through the LLBL, and fast solar wind will enhance such a transport process.

  16. THIN CURRENT SHEETS AND ASSOCIATED ELECTRON HEATING IN TURBULENT SPACE PLASMA

    Energy Technology Data Exchange (ETDEWEB)

    Chasapis, A.; Retinò, A.; Sahraoui, F.; Canu, P. [Laboratoire de Physique des Plasmas, Ecole Polytechnique, Palaiseau, F-91128 (France); Vaivads, A.; Khotyaintsev, Yu. V. [Swedish Institute of Space Physics, Uppsala (Sweden); Sundkvist, D. [Space Sciences Laboratory, University of California, Berkeley, CA (United States); Greco, A. [Dipartimento di Fisica, Universita della Calabria (Italy); Sorriso-Valvo, L., E-mail: alexandros.chasapis@lpp.polytechnique.fr [IMIP-CNR, U.O.S. LICRYL di Cosenza (Italy)

    2015-05-01

    Intermittent structures, such as thin current sheets, are abundant in turbulent plasmas. Numerical simulations indicate that such current sheets are important sites of energy dissipation and particle heating occurring at kinetic scales. However, direct evidence of dissipation and associated heating within current sheets is scarce. Here, we show a new statistical study of local electron heating within proton-scale current sheets by using high-resolution spacecraft data. Current sheets are detected using the Partial Variance of Increments (PVI) method which identifies regions of strong intermittency. We find that strong electron heating occurs in high PVI (>3) current sheets while no significant heating occurs in low PVI cases (<3), indicating that the former are dominant for energy dissipation. Current sheets corresponding to very high PVI (>5) show the strongest heating and most of the time are consistent with ongoing magnetic reconnection. This suggests that reconnection is important for electron heating and dissipation at kinetic scales in turbulent plasmas.

  17. A study of the formation and dynamics of the Earth's plasma sheet using ion composition data

    Science.gov (United States)

    Lennartsson, O. W.

    1994-01-01

    Over two years of data from the Lockheed Plasma Composition Experiment on the ISEE 1 spacecraft, covering ion energies between 100 eV/e and about 16 keV/e, have been analyzed in an attempt to extract new information about three geophysical issues: (1) solar wind penetration of the Earth's magnetic tail; (2) relationship between plasma sheet and tail lobe ion composition; and (3) possible effects of heavy terrestrial ions on plasma sheet stability.

  18. Relative contributions of terrestrial and solar wind ions in the plasma sheet

    Science.gov (United States)

    Lennartsson, W.; Sharp, R. D.

    A major uncertainty concerning the origins of plasma sheet ions is due to the fact that terrestrial H(+) can have similar fluxes and energies as H(+) from the solar wind. The situation is especially ambiguous during magnetically quiet conditions (AE less than 60 gamma) when H(+) typically contributes more than 90 percent of the plasma sheet ion population. In this study that problem is examined using a large data set obtained by the ISEE-1 Plasma Composition Experiment. The data suggest that one component of the H(+) increases in energy with increasing activity, roughly in proportion to 1/4 the energy of the He(++), whereas the other H(+) component has about the same energy at all activity levels, as do the O(+) and the He(+). If it is assumed that the H(+) of solar wind origin on the average has about the same energy-per-nucleon as the He(++), which is presumably almost entirely from the solar wind, then the data imply that as much as 20-30 percent of the H(+) can be of terrestrial origin even during quiet conditions.

  19. Relative contributions of terrestrial and solar wind ions in the plasma sheet

    Energy Technology Data Exchange (ETDEWEB)

    Lennartsson, W.; Sharp, R.D.

    1985-01-01

    A major uncertainty concerning the origins of plasma sheet ions is due to the fact that terrestrial H(+) can have similar fluxes and energies as H(+) from the solar wind. The situation is especially ambiguous during magnetically quiet conditions (AE less than 60 gamma) when H(+) typically contributes more than 90 percent of the plasma sheet ion population. In this study that problem is examined using a large data set obtained by the ISEE-1 Plasma Composition Experiment. The data suggest that one component of the H(+) increases in energy with increasing activity, roughly in proportion to 1/4 the energy of the He(++), whereas the other H(+) component has about the same energy at all activity levels, as do the O(+) and the He(+). If it is assumed that the H(+) of solar wind origin on the average has about the same energy-per-nucleon as the He(++), which is presumably almost entirely from the solar wind, then the data imply that as much as 20-30 percent of the H(+) can be of terrestrial origin even during quiet conditions.

  20. Thin Current Sheets and Associated Electron Heating in Turbulent Space Plasma

    Science.gov (United States)

    Chasapis, A.; Retinò, A.; Sahraoui, F.; Vaivads, A.; Khotyaintsev, Yu. V.; Sundkvist, D.; Greco, A.; Sorriso-Valvo, L.; Canu, P.

    2015-05-01

    Intermittent structures, such as thin current sheets, are abundant in turbulent plasmas. Numerical simulations indicate that such current sheets are important sites of energy dissipation and particle heating occurring at kinetic scales. However, direct evidence of dissipation and associated heating within current sheets is scarce. Here, we show a new statistical study of local electron heating within proton-scale current sheets by using high-resolution spacecraft data. Current sheets are detected using the Partial Variance of Increments (PVI) method which identifies regions of strong intermittency. We find that strong electron heating occurs in high PVI (>3) current sheets while no significant heating occurs in low PVI cases (5) show the strongest heating and most of the time are consistent with ongoing magnetic reconnection. This suggests that reconnection is important for electron heating and dissipation at kinetic scales in turbulent plasmas.

  1. Thinning and functionalization of few-layer graphene sheets by CF4 plasma treatment

    KAUST Repository

    Shen, Chao

    2012-05-24

    Structural changes of few-layer graphene sheets induced by CF4 plasma treatment are studied by optical microscopy and Raman spectroscopy, together with theoretical simulation. Experimental results suggest a thickness reduction of few-layer graphene sheets subjected to prolonged CF4 plasma treatment while plasma treatment with short time only leads to fluorine functionalization on the surface layer by formation of covalent bonds. Raman spectra reveal an increase in disorder by physical disruption of the graphene lattice as well as functionalization during the plasma treatment. The F/CF3 adsorption and the lattice distortion produced are proved by theoretical simulation using density functional theory, which also predicts p-type doping and Dirac cone splitting in CF4 plasma-treated graphene sheets that may have potential in future graphene-based micro/nanodevices.

  2. Bi-directional electrons in the near-Earth plasma sheet

    Directory of Open Access Journals (Sweden)

    K. Shiokawa

    Full Text Available We have studied the occurrence characteristics of bi-directional electron pitch angle anisotropy (enhanced flux in field-aligned directions, F^ /F|| > 1.5 at energies of 0.1–30 keV using plasma and magnetic field data from the AMPTE/IRM satellite in the near-Earth plasma sheet. The occurrence rate increases in the tailward direction from XGSM = - 9 RE to - 19 RE . The occurrence rate is also enhanced in the midnight sector, and furthermore, whenever the elevation angle of the magnetic field is large while the magnetic field intensity is small, B ~ 15 nT. From these facts, we conclude that the bi-directional electrons in the central plasma sheet are produced mainly in the vicinity of the neutral sheet and that the contribution from ionospheric electrons is minor. A high occurrence is also found after earthward high-speed ion flows, suggesting Fermi-type field-aligned electron acceleration in the neutral sheet. Occurrence characteristics of bi-directional electrons in the plasma sheet boundary layer are also discussed.

    Key words. Magnetospheric physics (magnetospheric configuration and dynamics; magnetotail; plasma sheet

  3. Study of the turbulence in the central plasma sheet using the CLUSTER satellite data

    Science.gov (United States)

    Stepanova, M.; Arancibia Riveros, K.; Bosqued, J.; Antonova, E.

    2008-05-01

    Recent studies are shown that the turbulent processes in the space plasmas are very important. It includes the behavior of the plasma sheet plasma during geomagnetic substorms and storms. Study of the plasma turbulence in the central plasma sheet was made using the CLUSTER satellite mission data. For this studies we used the Cluster Ion Spectrometry experiment (CIS), and fluxgate magnetometer (FGM) data for studying fluctuations of the plasma bulk velocity and geomagnetic field fluctuations for different levels of geomagnetic activity and different locations inside the plasma sheet. Case studies for the orbits during quiet geomagnetic conditions, different phases of geomagnetic substroms and storms showed that the properties of plasma turbulence inside the sheet differ significantly for all afore mentioned cases. Variations in the probability distribution functions, flatness factors, local intermittency measure parameters, and eddy diffusion coefficients indicate that the turbulence increases significantly during substorm growth and expansion phases and decreases slowly to the initial level during the recovery phase. It became even stronger during the storm main phase.

  4. A Modified Porous Titanium Sheet Prepared by Plasma-Activated Sintering for Biomedical Applications

    Directory of Open Access Journals (Sweden)

    Yukimichi Tamaki

    2010-01-01

    Full Text Available This study aimed to develop a contamination-free porous titanium scaffold by a plasma-activated sintering within an originally developed TiN-coated graphite mold. The surface of porous titanium sheet with or without a coated graphite mold was characterized. The cell adhesion property of porous titanium sheet was also evaluated in this study. The peak of TiC was detected on the titanium sheet processed with the graphite mold without a TiN coating. Since the titanium fiber elements were directly in contact with the carbon graphite mold during processing, surface contamination was unavoidable event in this condition. The TiC peak was not detectable on the titanium sheet processed within the TiN-coated carbon graphite mold. This modified plasma-activated sintering with the TiN-coated graphite mold would be useful to fabricate a contamination-free titanium sheet. The number of adherent cells on the modified titanium sheet was greater than that of the bare titanium plate. Stress fiber formation and the extension of the cells were observed on the titanium sheets. This modified titanium sheet is expected to be a new tissue engineering material in orthopedic bone repair.

  5. Substorm effects on the plasma sheet on composition on March 22, 1979 (CDAW 6)

    Energy Technology Data Exchange (ETDEWEB)

    Lennartsson, W.; Sharp, R.D.; Zwickl, R.D.

    1985-02-01

    Data from the Plasma Composition Experiment on ISSE 1, covering the energy range 0.1--16 keV/e, show that a dramatic change took place in the plasma sheet ion composition in conjunction with the magnetic substorm activity on March 22, 1979. Beginning about 1124 UT the ion population at the ISEE 1 location changed from what appeared to be predominantly ions from the solar wind to a mixture of comparable numbers of solar wind and terrestrial ions. ISEE 1 was inbound in the predawn sector during this time, and the plasma composition experiment provided data from Rapprox. =21 R/sub E/ and LTapprox. =0130, down to Rapprox. =3 R/sub E/ and LTapprox. =0530. Prior to the substorm activity about 90--95% of the ion density was due to H/sup +/ and He/sup + +/ ions, which appeared to be mostly of solar wind origin. The H/sup +/ and He/sup + +/ components, each approximated by a Maxwell-Boltzmann distribution, had a temperature ratio T(He/sup + +/)/T(H/sup +/)approx. =4 and a density ratio n(He/sup + +/)/n(H/sup +/)approx. =1.5--3%. Both values are consistent with measurements made concurrently in the solar wind by the plasma experiment on ISSE 3. The remaining 5--10% of the density was due mainly to O/sup +/ and He/sup +/ ions of ionospheric origin. All four ion populations had broad energy spectra with mean energies of several keV/e.

  6. Occurrence and location of concentrated load and generator regions observed by Cluster in the plasma sheet

    Directory of Open Access Journals (Sweden)

    M. Hamrin

    2009-11-01

    Full Text Available Here, and in a companion paper by Hamrin et al. (2009 [Scale size and life time of energy conversion regions observed by Cluster in the plasma sheet], we investigate localized energy conversion regions (ECRs in the Earth's plasma sheet. In total we have studied 151 ECRs within 660 h of plasma sheet data from the summer and fall of 2001 when Cluster was close to apogee at an altitude of about 15–20 RE. Cluster offers appropriate conditions for the investigation of energy conversion by the evaluation of the power density, E·J, where E is the electric field and J the current density. From the sign of the power density, we have identified more than three times as many Concentrated Load Regions (CLRs as Concentrated Generator Regions (CGRs. We also note that the CLRs appear to be stronger. To our knowledge, these are the first in situ observations confirming the general notion of the plasma sheet, on the average, behaving as a load. At the same time the plasma sheet appears to be highly structured, with energy conversion occurring in both directions between the fields and the particles. From our data we also find that the CLRs appear to be located closer to the neutral sheet, while CGRs prefer locations towards the plasma sheet boundary layer (PSBL. For both CLRs and CGRs, E and J in the GSM y (cross-tail direction dominate the total power density, even though the z contribution occasionally can be significant. The prevalence of the y-direction seems to be weaker for the CGRs, possibly related to a higher fluctuation level near the PSBL.

  7. NLTE4 Plasma Population Kinetics Database

    Science.gov (United States)

    SRD 159 NLTE4 Plasma Population Kinetics Database (Web database for purchase)   This database contains benchmark results for simulation of plasma population kinetics and emission spectra. The data were contributed by the participants of the 4th Non-LTE Code Comparison Workshop who have unrestricted access to the database. The only limitation for other users is in hidden labeling of the output results. Guest users can proceed to the database entry page without entering userid and password.

  8. Thermal Structure and Dynamics in Supra-arcade Downflows and Flare Plasma Sheets

    Science.gov (United States)

    Reeves, K.; Hanneman, W.; Freed, M.; McKenzie, D. E.

    2014-12-01

    During a long duration solar flare, a hot plasma sheet is commonly formed above the flare loops. Often produced within this sheet are down-flowing voids referred to as supra-arcade downflows, thought to be the products of a patchy reconnection process. Models differ on the question of whether the downflows should be hotter than the surrounding plasma or not. We use imaging data from Hinode/XRT and SDO/AIA to determine the thermal structure of the plasma sheet and downflows. We find that the temperatures of the plasma within the downflows are either roughly the same as or lower than the surrounding fan plasma. This result implies that a mechanism for forming the voids that involves a sunward directed hydrodynamic shock pattern combined with perpendicular magnetic shock is unlikely. Additionally, we use the high cadence AIA data to trace the velocity fields in these regions through the use of a local correlation tracking algorithm. Through these measurements, we can determine areas of diverging velocity fields, as well as velocity shear fields and correlate them with temperature changes in order to understand the heating mechanisms in the plasma sheet. This work is supported by under contract SP02H1701R from Lockheed-Martin to SAO, contract NNM07AB07C from NASA to SAO and NASA grant numbers NNX13AG54G and NNX14AD43G

  9. Survey of 0. 1- to 16-keV/e plasma sheet ion composition

    Energy Technology Data Exchange (ETDEWEB)

    Lennartsson, W.; Shelley, E.G.

    1986-03-01

    A large statistical survey of the 0.1- to 16-keV/e plasma sheet ion composition has been carried out using data obtained by the Plasma Composition Experiment on ISEE 1 between 10 and 23 R/sub E/ during 1978 and 1979. This survey includes more than 10 times the quantity of data used in earlier studies of the same topic and makes it possible to investigate in finer detail the relationship between the ion composition and the substorm activity. The larger data base also makes it possible for the first time to study the spatial distribution of the principal ion species. As found in previous studies, the ion composition has a large variance at any given value of the AE index, but a number of distinct trends emerge when the data are averaged at each activity level. During quiet conditions the plasma sheet is dominated by ions of solar origin (H/sup +/ and He/sup + +/), as found in earlier studies, and these ions are most numerous during extended periods of very low activity (AE< or approx. =30 ..gamma..). The quiet time density of these ions is particularly large in the flanks of the plasma sheet (GSM Yapprox. +- 10 R/sub E/), where it is about twice as large as it is near the central axis of the plasma sheet (Y = Z = 0). In contrast, the energy of these ions peaks near the central axis.

  10. Early results of microwave transmission experiments through an overly dense rectangular plasma sheet with microparticle injection

    Science.gov (United States)

    Gillman, Eric D.; Amatucci, W. E.

    2014-06-01

    These experiments utilize a linear hollow cathode to create a dense, rectangular plasma sheet to simulate the plasma layer surrounding vehicles traveling at hypersonic velocities within the Earth's atmosphere. Injection of fine dielectric microparticles significantly reduces the electron density and therefore lowers the electron plasma frequency by binding a significant portion of the bulk free electrons to the relatively massive microparticles. Measurements show that microwave transmission through this previously overly dense, impenetrable plasma layer increases with the injection of alumina microparticles approximately 60 μm in diameter. This method of electron depletion is a potential means of mitigating the radio communications blackout experienced by hypersonic vehicles.

  11. Oxygen plasma-treated thermoresponsive polymer surfaces for cell sheet engineering.

    Science.gov (United States)

    Shimizu, Kazunori; Fujita, Hideaki; Nagamori, Eiji

    2010-06-01

    Although cell sheet tissue engineering is a potent and promising method for tissue engineering, an increase of mechanical strength of a cell sheet is needed for easy manipulation of it during transplantation or 3D tissue fabrication. Previously, we developed a cell sheet-polymer film complex that had enough mechanical strength that can be manipulated even by tweezers (Fujita et al., 2009. Biotechnol Bioeng 103(2): 370-377). We confirmed the polymer film involving a temperature sensitive polymer and extracellular matrix (ECM) proteins could be removed by lowering temperature after transplantation, and its potential use in regenerative medicine was demonstrated. However, the use of ECM proteins conflicted with high stability in long-term storage and low cost. In the present study, to overcome these drawbacks, we employed the oxygen plasma treatment instead of using the ECM proteins. A cast and dried film of thermoresponsive poly-N-isopropylacrylamide (PNIPAAm) was fabricated and treated with high-intensity oxygen plasma. The cells became possible to adhere to the oxygen plasma-treated PNIPAAm surface, whereas could not to the inherent surface of bulk PNIPAAm without treatment. Characterizations of the treated surface revealed the surface had high stability. The surface roughness, wettability, and composition were changed, depending on the plasma intensity. Interestingly, although bulk PNIPAAm layer had thermoresponsiveness and dissolved below lower critical solution temperature (LCST), it was found that the oxygen plasma-treated PNIPAAm surface lost its thermoresponsiveness and remained insoluble in water below LCST as a thin layer. Skeletal muscle C2C12 cells could be cultured on the oxygen plasma-treated PNIPAAm surface, a skeletal muscle cell sheet with the insoluble thin layer could be released in the medium, and thus the possibility of use of the cell sheet for transplantation was demonstrated.

  12. In Situ Observations of Ion Scale Current Sheets and Associated Electron Heating in Turbulent Space Plasmas

    Science.gov (United States)

    Chasapis, A.; Retino, A.; Sahraoui, F.; Greco, A.; Vaivads, A.; Khotyaintsev, Y. V.; Sundkvist, D. J.; Canu, P.

    2014-12-01

    We present a statistical study of ion-scale current sheets in turbulent space plasma. The study was performed using in situ measurements from the Earth's magnetosheath downstream of the quasi-parallel shock. Intermittent structures were identified using the Partial Variance of Increments method. We studied the distribution of the identified structures as a function of their magnetic shear angle, the PVI index and the electron heating. The properties of the observed current sheets were different for high (>3) and low (3) structures that accounted for ~20% of the total. Those current sheets have high magnetic shear (>90 degrees) and were observed mostly in close proximity to the bow shock with their numbers reducing towards the magnetopause. Enhancement of the estimated electron temperature within these current sheets suggest that they are important for local electron heating and energy dissipation.

  13. Plasma Sheet Actuator Driven by Repetitive Nanosecond Pulses with a Negative DC Component

    Institute of Scientific and Technical Information of China (English)

    宋慧敏; 张乔根; 李应红; 贾敏; 吴云; 梁华

    2012-01-01

    A type of electrical discharge called sliding discharge was developed to generate plasma aerodynamic actuation for flow control. A three-electrode plasma sheet actuator driven by repetitive nanosecond pulses with a negative DC component was used to generate sliding discharge, which can be called nanosecond-pulse sliding discharge. The phenomenology and behaviour of the plasma sheet actuator were investigated experimentally. Discharge morphology shows that the formation of nanosecond-pulse sliding discharge is dependent on the peak value of the repetitive nanosecond pulses and negative DC component applied on the plasma sheet actuator. Compared to dielectric barrier discharge (DBD), the extension of plasma in nanosecond-pulse sliding discharge is quasi-diffusive, stable, longer and more intensive. Test results of particle image velocimetry demonstrate that the negative DC component applied to a third electrode could significantly modify the topology of the flow induced by nanosecond-pulse DBD. Body force induced by the nanosecond-pulse sliding discharge can be approximately in the order of mN. Both the maximum velocity and the body force induced by sliding discharge increase significantly as compared to single DBD. Therefore, nanosecond-pulse sliding discharge is a preferable plasma aerodynamic actuation generation mode, which is very promising in the field of aerodynamics.

  14. Resonant scattering of plasma sheet electrons leading to diffuse auroral precipitation: 1. Evaluation for electrostatic electron cyclotron harmonic waves

    Science.gov (United States)

    Ni, Binbin; Thorne, Richard M.; Horne, Richard B.; Meredith, Nigel P.; Shprits, Yuri Y.; Chen, Lunjin; Li, Wen

    2011-04-01

    Using statistical wave power spectral profiles obtained from CRRES and the latitudinal distributions of wave propagation modeled by the HOTRAY code, a quantitative analysis has been performed on the scattering of plasma sheet electrons into the diffuse auroral zone by multiband electrostatic electron cyclotron harmonic (ECH) emissions near L = 6 within the 0000-0600 MLT sector. The results show that ECH wave scattering of plasma sheet electrons varies from near the strong diffusion rate (timescale of an hour or less) during active times with peak wave amplitudes of an order of 1 mV/m to very weak scattering (on the timescale of >1 day) during quiet conditions with typical wave amplitudes of tenths of mV/m. However, for the low-energy (˜100 eV to below 2 keV) electron population mainly associated with the diffuse auroral emission, ECH waves are only responsible for rapid pitch angle diffusion (occasionally near the limit of strong diffusion) for a small portion of the electron population with pitch angles αeq 70°. Computations of the bounce-averaged coefficients of momentum diffusion and (pitch angle, momentum) mixed diffusion indicate that both mixed diffusion and energy diffusion of plasma sheet electrons due to ECH waves are very small compared to pitch angle diffusion and that ECH waves have little effect on local electron acceleration. Consequently, the multiple harmonic ECH emissions cannot play a dominant role in the occurrence of diffuse auroral precipitation near L = 6, and other wave-particle interaction mechanisms, such as whistler mode chorus-driven resonant scattering, are required to explain the global distribution of diffuse auroral precipitation and the formation of the pancake distribution in the inner magnetosphere.

  15. On the plasma-based growth of ‘flowing’ graphene sheets at atmospheric pressure conditions

    Science.gov (United States)

    Tsyganov, D.; Bundaleska, N.; Tatarova, E.; Dias, A.; Henriques, J.; Rego, A.; Ferraria, A.; Abrashev, M. V.; Dias, F. M.; Luhrs, C. C.; Phillips, J.

    2016-02-01

    A theoretical and experimental study on atmospheric pressure microwave plasma-based assembly of free standing graphene sheets is presented. The synthesis method is based on introducing a carbon-containing precursor (C2H5OH) through a microwave (2.45 GHz) argon plasma environment, where decomposition of ethanol molecules takes place and carbon atoms and molecules are created and then converted into solid carbon nuclei in the ‘colder’ nucleation zones. A theoretical model previously developed has been further updated and refined to map the particle and thermal fluxes in the plasma reactor. Considering the nucleation process as a delicate interplay between thermodynamic and kinetic factors, the model is based on a set of non-linear differential equations describing plasma thermodynamics and chemical kinetics. The model predictions were validated by experimental results. Optical emission spectroscopy was applied to detect the plasma emission related to carbon species from the ‘hot’ plasma zone. Raman spectroscopy, scanning electron microscopy (SEM), and x-ray photoelectron spectroscopy (XPS) techniques have been applied to analyze the synthesized nanostructures. The microstructural features of the solid carbon nuclei collected from the colder zones of plasma reactor vary according to their location. A part of the solid carbon was deposited on the discharge tube wall. The solid assembled from the main stream, which was gradually withdrawn from the hot plasma region in the outlet plasma stream directed to a filter, was composed by ‘flowing’ graphene sheets. The influence of additional hydrogen, Ar flow rate and microwave power on the concentration of obtained stable species and carbon-dicarbon was evaluated. The ratio of sp3/sp2 carbons in graphene sheets is presented. A correlation between changes in C2 and C number densities and sp3/sp2 ratio was found.

  16. Kink-like mode of a double gradient instability in a compressible plasma current sheet

    Science.gov (United States)

    Korovinskiy, D.B.; Ivanova, V.V.; Erkaev, N.V.; Semenov, V.S.; Ivanov, I.B.; Biernat, H.K.; Zellinger, M.

    2011-01-01

    A linear MHD instability of the electric current sheet, characterized by a small normal magnetic field component, varying along the sheet, is investigated. The tangential magnetic field component is modeled by a hyperbolic function, describing Harris-like variations of the field across the sheet. For this problem, which is formulated in a 3D domain, the conventional compressible ideal MHD equations are applied. By assuming Fourier harmonics along the electric current, the linearized 3D equations are reduced to 2D ones. A finite difference numerical scheme is applied to examine the time evolution of small initial perturbations of the plasma parameters. This work is an extended numerical study of the so called “double gradient instability”, – a possible candidate for the explanation of flapping oscillations in the magnetotail current sheet, which has been analyzed previously in the framework of a simplified analytical approach for an incompressible plasma. The dispersion curve is obtained for the kink-like mode of the instability. It is shown that this curve demonstrates a quantitative agreement with the previous analytical result. The development of the instability is investigated also for various enhanced values of the normal magnetic field component. It is found that the characteristic values of the growth rate of the instability shows a linear dependence on the square root of the parameter, which scales uniformly the normal component of the magnetic field in the current sheet. PMID:22053125

  17. A study of the formation and dynamics of the Earth's plasma sheet using ion composition data

    Energy Technology Data Exchange (ETDEWEB)

    Lennartsson, O.W.

    1994-04-01

    Over two years of data from the Lockheed Plasma Composition Experiment on the ISEE 1 spacecraft, covering ion energies between 100 eV/e and about 16 keV/e, have been analyzed in an attempt to extract new information about three geophysical issues: (1) solar wind penetration of the Earth's magnetic tail; (2) relationship between plasma sheet and tail lobe ion composition; and (3) possible effects of heavy terrestrial ions on plasma sheet stability.

  18. Scale size and life time of energy conversion regions observed by Cluster in the plasma sheet

    Directory of Open Access Journals (Sweden)

    M. Hamrin

    2009-11-01

    Full Text Available In this article, and in a companion paper by Hamrin et al. (2009 [Occurrence and location of concentrated load and generator regions observed by Cluster in the plasma sheet], we investigate localized energy conversion regions (ECRs in Earth's plasma sheet. From more than 80 Cluster plasma sheet crossings (660 h data at the altitude of about 15–20 RE in the summer and fall of 2001, we have identified 116 Concentrated Load Regions (CLRs and 35 Concentrated Generator Regions (CGRs. By examining variations in the power density, E·J, where E is the electric field and J is the current density obtained by Cluster, we have estimated typical values of the scale size and life time of the CLRs and the CGRs. We find that a majority of the observed ECRs are rather stationary in space, but varying in time. Assuming that the ECRs are cylindrically shaped and equal in size, we conclude that the typical scale size of the ECRs is 2 RE≲ΔSECR≲5 RE. The ECRs hence occupy a significant portion of the mid altitude plasma sheet. Moreover, the CLRs appear to be somewhat larger than the CGRs. The life time of the ECRs are of the order of 1–10 min, consistent with the large scale magnetotail MHD simulations of Birn and Hesse (2005. The life time of the CGRs is somewhat shorter than for the CLRs. On time scales of 1–10 min, we believe that ECRs rise and vanish in significant regions of the plasma sheet, possibly oscillating between load and generator character. It is probable that at least some of the observed ECRs oscillate energy back and forth in the plasma sheet instead of channeling it to the ionosphere.

  19. A Statistical study of plasma sheet oscillations with kinetic ballooning/interchange instability signatures using THEMIS spacecraft

    Science.gov (United States)

    Jurisic, Mirjana; Panov, Evgeny; Nakamura, Rumi; Baumjohann, Wolfgang

    2016-04-01

    We use THEMIS data from 2010-2012 tail seasons to collect observations of plasma sheet oscillations with kinetic ballooning/interchange instability (BICI) signatures. Over seventy observations with closely located THEMIS probes P3-P5 reveal that BICI-like plasma sheet oscillations may appear at different magnetic local time. For these, we derive background plasma sheet parameters such as BZ, δBZ/δx and plasma beta, and investigate solar wind conditions. We also estimate the proper parameters of BICI-like oscillations such as frequency and amplitude. Based on this, we search for a relation between the background plasma sheet parameters and the proper parameters of BICI-like oscillations.

  20. Geotail observations of temperature anisotropy of the two-component protons in the dusk plasma sheet

    Directory of Open Access Journals (Sweden)

    M. N. Nishino

    2007-03-01

    Full Text Available In search for clues towards the understanding of the cold plasma sheet formation under northward IMF, we study the temperature anisotropy of the two-component protons in the plasma sheet near the dusk low-latitude boundary observed by the Geotail spacecraft. The two-component protons result from mixing of the cold component from the solar wind and the hot component of the magnetospheric origin, and may be the most eloquent evidence for the transport process across the magnetopause. The cold component occasionally has a strong anisotropy in the dusk flank, and the sense of the anisotropy depends on the observed locations: the parallel temperature is enhanced in the tail flank while the perpendicular temperature is enhanced on the dayside. The hot component is nearly isotropic in the tail while the perpendicular temperature is enhanced on the dayside. We discuss possible mechanism that can lead to the observed temperature anisotropies.

  1. Distribution of energetic oxygen and hydrogen in the near-Earth plasma sheet

    CERN Document Server

    Kronberg, E A; Haaland, S E; Daly, P W; Delcourt, D C; Luo, H; Kistler, L M; Dandouras, I

    2016-01-01

    The spatial distributions of different ion species are useful indicators for plasma sheet dynamics. In this statistical study based on 7 years of Cluster observations, we establish the spatial distributions of oxygen ions and protons at energies from 274 to 955 keV, depending on geomagnetic and solar wind (SW) conditions. Compared with protons, the distribution of energetic oxygen has stronger dawn-dusk asymmetry in response to changes in the geomagnetic activity. When the interplanetary magnetic field (IMF) is directed southward, the oxygen ions show significant acceleration in the tail plasma sheet. Changes in the SW dynamic pressure ($\\mathit{P}_{dyn}$) affect the oxygen and proton intensities in the same way. The energetic protons show significant intensity increases at the near-Earth duskside during disturbed geomagnetic conditions, enhanced SW $\\mathit{P}_{dyn}$, and southward IMF, implying there location of effective inductive acceleration mechanisms and a strong duskward drift due to the increase of t...

  2. On the 3-dimensional structure of plasmoids. [in near-earth plasma sheets

    Science.gov (United States)

    Hughes, W. J.; Sibeck, D. G.

    1987-01-01

    The hypothesis that the IMF penetrates plasmoids causing them to be three- rather than two-dimensional is tested by comparing observations of By within plasmoids and related tail structures to upstream IMF By data. The magnetic topologies that result from the mergings of closed plasma sheet flux tubes and open tail lobe flux tubes at a near-earth neutral line, and merging near the tail flanks are described and studied. The particle signals and isotropic electron distributions are examined. It is observed that the IMF By penetrates plasmoids and that their structure is three-dimensional. In the three-dimensional model of plasmoids the reconnected plasma sheet field lines form a magnetic flux-ropelike structure. The three-dimensional model is utilized to analyze stagnant, slowly moving and earthward moving structures.

  3. Effect of the initial plasma parameters on the structure of the current sheets developing in two-dimensional magnetic fields with a null line

    Science.gov (United States)

    Ostrovskaya, G. V.; Frank, A. G.; Bogdanov, S. Yu.

    2010-07-01

    The effect of the initial plasma parameters on the structure of the plasma of the current sheets that form in two-dimensional magnetic fields with a null line is studied by holographic interferometry. The evolution of the plasma sheets that develop in an initial low-density plasma, where a gas is mainly ionized by a pulse current passing through the plasma and initiating the formation of a current sheet, has been comprehensively studied for the first time. At the early stage of evolution, the spatial structure of such a plasma sheet differs substantially from the classic current sheets forming in a dense plasma. Nevertheless, extended plasma sheets with similar parameters form eventually irrespective of the initial plasma density.

  4. Plasma sheet ion composition at various levels of geomagnetic and solar activity

    Science.gov (United States)

    Lennartsson, W.

    1987-08-01

    The data obtained in the earth's plasma sheet by the Plasma Composition Experiment on the ISEE-1 spacecraft are briefly reexamined. The data are shown in the form of statistically averaged bulk parameters for the four major ions H(+), He(2+), He(+), and O(+) to illustrate the apparent mixture of solar and terrestrial ions, a mixture that varies with geomagnetic and other conditions. Some major differences in the statistical properties of different ions, which may have a bearing on the physics of the solar wind-magnetosphere interaction, are highlighted.

  5. Sounding of the plasma sheet in the deep geomagnetic tail using energetic particles

    Energy Technology Data Exchange (ETDEWEB)

    Daly, P.W.; Wenzel, K.; Sanderson, T.R.

    1984-10-01

    Energetic ions (E>35 keV) at 90/sup 0/ to the magnetic field line are measured on ISEE-3 in the distant geomagnetic tail and are used as tracers of the particle density during two encounters with the plasma sheet at 210 and 128 earth radii from the earth. Because of the finite gyroradius (2400 km) of these (assumed) protons, different orientation about the magnetic field measure the intensity of different locations, allowing a separation of spatial from temporal variations. Density contour maps of the plasma hseet are constructed, demonstrating the wavy nature of this regime, as well as the existence of density layers within it.

  6. On the problem of Plasma Sheet Boundary Layer identification from plasma moments in Earth's magnetotail

    Directory of Open Access Journals (Sweden)

    E. E. Grigorenko

    2012-09-01

    Full Text Available The problem of identification of the interface region between the lobe and the Plasma Sheet (PS – the Plasma Sheet Boundary Layer (PSBL – using ion moments and magnetic field data often arises in works devoted to statistical studies of various PSBL phenomena. Our experience in the identification of this region based on the analysis of ion velocity distribution functions demonstrated that plasma parameters, such as the ion density and bulk velocity, the plasma beta or the dynamic pressure vary widely depending on the state of magnetotail activity. For example, while field-aligned beams of accelerated ions are often observed propagating along the lobeward edge of the PSBL there are times when no signatures of these beams could be observed. In the last case, a spacecraft moving from the lobe region to the PS registers almost isotropic PS-like ion velocity distribution. Such events may be classified as observations of the outer PS region. In this paper, we attempt to identify ion parameter ranges or their combinations that result in a clear distinction between the lobe, the PSBL and the adjacent PS or the outer PS regions. For this we used 100 crossings of the lobe-PSBL-PS regions by Cluster spacecraft (s/c made in different periods of magnetotail activity. By eye inspection of the ion distribution functions we first identify and separate the lobe, the PSBL and the adjacent PS or outer PS regions and then perform a statistical study of plasma and magnetic field parameters in these regions. We found that the best results in the identification of the lobe-PSBL boundary are reached when one uses plasma moments, namely the ion bulk velocity and density calculated not for the entire energy range, but for the energies higher than 2 keV. In addition, we demonstrate that in many cases the plasma beta fails to correctly identify and separate the PSBL and the adjacent PS or the outer PS regions.

  7. Formation and evolution of flapping and ballooning waves in magnetospheric plasma sheet

    Science.gov (United States)

    Ma, J. Z. G.; Hirose, A.

    2016-05-01

    By adopting Lembége & Pellat's 2D plasma-sheet model, we investigate the flankward flapping motion and Sunward ballooning propagation driven by an external source (e.g., magnetic reconnection) produced initially at the sheet center. Within the ideal MHD framework, we adopt the WKB approximation to obtain the Taylor-Goldstein equation of magnetic perturbations. Fourier spectral method and Runge-Kutta method are employed in numerical simulations, respectively, under the flapping and ballooning conditions. Studies expose that the magnetic shears in the sheet are responsible for the flapping waves, while the magnetic curvature and the plasma gradient are responsible for the ballooning waves. In addition, the flapping motion has three phases in its temporal development: fast damping phase, slow recovery phase, and quasi-stabilized phase; it is also characterized by two patterns in space: propagating wave pattern and standing wave pattern. Moreover, the ballooning modes are gradually damped toward the Earth, with a wavelength in a scale size of magnetic curvature or plasma inhomogeneity, only 1-7% of the flapping one; the envelops of the ballooning waves are similar to that of the observed bursty bulk flows moving toward the Earth.

  8. Effect of Inductive Coil Geometry and Current Sheet Trajectory of a Conical Theta Pinch Pulsed Inductive Plasma Accelerator

    Science.gov (United States)

    Hallock, Ashley K.; Polzin, Kurt A.; Bonds, Kevin W.; Emsellem, Gregory D.

    2011-01-01

    Results are presented demonstrating the e ect of inductive coil geometry and current sheet trajectory on the exhaust velocity of propellant in conical theta pinch pulsed induc- tive plasma accelerators. The electromagnetic coupling between the inductive coil of the accelerator and a plasma current sheet is simulated, substituting a conical copper frustum for the plasma. The variation of system inductance as a function of plasma position is obtained by displacing the simulated current sheet from the coil while measuring the total inductance of the coil. Four coils of differing geometries were employed, and the total inductance of each coil was measured as a function of the axial displacement of two sep- arate copper frusta both having the same cone angle and length as the coil but with one compressed to a smaller size relative to the coil. The measured relationship between total coil inductance and current sheet position closes a dynamical circuit model that is used to calculate the resulting current sheet velocity for various coil and current sheet con gura- tions. The results of this model, which neglects the pinching contribution to thrust, radial propellant con nement, and plume divergence, indicate that in a conical theta pinch ge- ometry current sheet pinching is detrimental to thruster performance, reducing the kinetic energy of the exhausting propellant by up to 50% (at the upper bound for the parameter range of the study). The decrease in exhaust velocity was larger for coils and simulated current sheets of smaller half cone angles. An upper bound for the pinching contribution to thrust is estimated for typical operating parameters. Measurements of coil inductance for three di erent current sheet pinching conditions are used to estimate the magnetic pressure as a function of current sheet radial compression. The gas-dynamic contribution to axial acceleration is also estimated and shown to not compensate for the decrease in axial electromagnetic acceleration

  9. Cluster and TC-1 observation of magnetic holes in the plasma sheet

    Directory of Open Access Journals (Sweden)

    W. J. Sun

    2012-03-01

    Full Text Available Magnetic holes with relatively small scale sizes, detected by Cluster and TC-1 in the magnetotail plasma sheet, are studied in this paper. It is found that these magnetic holes are spatial structures and they are not magnetic depressions generated by the flapping movement of the magnetotail current sheet. Most of the magnetic holes (93% were observed during intervals with Bz larger than Bx, i.e. they are more likely to occur in a dipolarized magnetic field topology. Our results also suggest that the occurrence of these magnetic holes might have a close relationship with the dipolarization process. The magnetic holes typically have a scale size comparable to the local proton Larmor radius and are accompanied by an electron energy flux enhancement at a 90° pitch angle, which is quite different from the previously observed isotropic electron distributions inside magnetic holes in the plasma sheet. It is also shown that most of the magnetic holes occur in marginally mirror-stable environments. Whether the plasma sheet magnetic holes are generated by the mirror instability related to ions or not, however, is unknown. Comparison of ratios, scale sizes and propagation direction of magnetic holes detected by Cluster and TC-1, suggests that magnetic holes observed in the vicinity of the TC-1 orbit (~7–12 RE are likely to be further developed than those observed by Cluster (~7–18 RE.

  10. Plasma-filled rippled wall rectangular backward wave oscillator driven by sheet electron beam

    Indian Academy of Sciences (India)

    A Hadap; J Mondal; K C Mittal; K P Maheshwari

    2011-03-01

    Performance of the backward wave oscillator (BWO) is greatly enhanced with the introduction of plasma. Linear theory of the dispersion relation and the growth rate have been derived and analysed numerically for plasma-filled rippled wall rectangular waveguide driven by sheet electron beam. To see the effect of plasma on the TM01 cold wave structure mode and on the generated frequency, the parameters used are: relativistic factor = 1.5 (i.e. / = 0.741), average waveguide height 0 = 1.445 cm, axial corrugation period 0 = 1.67 cm, and corrugation amplitude = 0.225 cm. The plasma density is varied from zero to 2 × 1012 cm-3. The presence of plasma tends to raise the TM01 mode cut-off frequency (14 GH at 2 × 1012 cm-3 plasma density) relative to the vacuum cut-off frequency (5 GH) which also causes a decrease in the group velocity everywhere, resulting in a flattening of the dispersion relation. With the introduction of plasma, an enhancement in absolute instability was observed.

  11. Three-dimensional particle simulation of plasma instabilities and collisionless reconnection in a current sheet

    Energy Technology Data Exchange (ETDEWEB)

    Horiuchi, Ritoku; Sato, Tetsuya [Theory and Computer Simulation Center, National Inst. for Fusion Science, Toki, Gifu (Japan)

    1999-06-01

    Generation of anomalous resistivity and dynamical development of collisionless reconnection in the vicinity of a magnetically neutral sheet are investigated by means of a three-dimensional particle simulation. For no external driving source, two different types of plasma instabilities are excited in the current layer. The lower hybrid drift instability (LHDI) is observed to grow in the periphery of current layer in an early period, while a drift kink instability (DKI) is triggered at the neutral sheet in a late period as a result of the nonlinear deformation of the current sheet by the LHDI. A reconnection electric field grows at the neutral sheet in accordance with the excitation of the DKI. When an external driving field exists, the convective electric field penetrates into the current layer through the particle kinetic effect and collisionless reconnection is triggered by the convective electric field earlier than the DKI is excited. It is also found that the anisotropic ion distribution is formed through the anomalous ion heating by the DKI. (author)

  12. Responses of properties in the plasma sheet and at the geosynchronous orbit to interplanetary shock

    Institute of Scientific and Technical Information of China (English)

    YAO Li; LIU ZhenXing; ZUO PingBing; ZHANG LingQian; DUAN SuPing

    2009-01-01

    On July 22,2004,the WIND spacecraft detected a typical interplanetary shock. There was sustaining weak southward magnetic field in the preshock region and the southward field was suddenly enhanced across the shock front (i.e.,southward turning). When the shock impinged on the magnetosphere,the magnetospheric plasma convection was abruptly enhanced in the central plasma sheet,which was directly observed by both the TC-1 and Cluster spacecraft located in different regions. Simultaneously,the Cluster spacecraft observed that the dawn-to-dusk electric field was abruptly enhanced. The variations of the magnetic field observed by TC-1,Cluster,GOES-10 and GOES-12 that were distributed in different regions in the plasma sheet and at the geosynchronous orbit are obviously distinct. TC-1 observations showed that the magnetic intensity kept almost unchanged and the elevation angle decreased,but the Cluster spacecraft,which was also in the plasma sheet and was further from the equator,observed that the magnetic field was obviously enhanced. Simultaneously,GOES-12 located near the midnight observed that the magnetic intensity sharply increased and the elevation angle decreased,but GOES-10 located in the dawn side observed that the magnetic field was merely compressed with its three components all sharply increasing. Furthermore,the energetic proton and electron fluxes at nearly all channels observed by five LANL satellites located at different magnetic local times (MLTs) all showed impulsive enhancements due to the compression of the shock. The responses of the energetic particles were much evident on the dayside than those on the nightside. Especially the responses near the midnight were rather weak. In this paper,the possible reasonable physical explanation to above observations is also discussed. All the shock-induced responses are the joint effects of the solar wind dynamic pressure pulse and the magnetic field southward turning.

  13. Alfven Waves in a Plasma Sheet Boundary Layer Associated with Near-Tail Magnetic Reconnection

    Institute of Scientific and Technical Information of China (English)

    YUAN Zhi-Gang; DENG Xiao-Hua; PANG Ye; LI Shi-You; WANG Jing-Fang

    2007-01-01

    We report observations from Geotail satellite showing that large Poynting fluxes associated with Alfven waves in the plasma sheet boundary layer(PSBL) occur in the vicinity of the near-tail reconnection region on 10 December 1996.During the period of large Poynting fluxex,Geotail also observed strong tailward plasma flws.These observations demonstrate the importance of near-tail reconnection process as the energy source of Alfven waves in the PSBL.Strong tailward(Earthward)plasma flows ought to be an important candidate in generating Alfven waves.Furthermore,the strong pertutbations not only of the magnetic field but also of the electric field observed in the PSBL indicate that the PSBL plays an important role in the generation and propagation of the energy flux associated with Alfven waves.

  14. Survey of 0.1- to 16-keV/e plasma sheet ion composition

    Science.gov (United States)

    Lennartsson, W.; Shelley, E. G.

    1986-03-01

    An analysis is performed of all plasma sheet data collected in 1978-79 in order to discern statistical trends in the data. Attention is focused on the bulk parameters of 0.1-16 keV/e plasma sheet ions detected by the Plasma Composition Experiment on the ISEE 1 satellite. The data were collected at 10-23 earth radii, and are averaged for various levels of activity in the AE index. Solar H(+) and He(2+) ions dominate during quiet periods and possess energies similar to those of the solar wind when the quiet period lasts several hours. Increasing AE index values eventually lead to a replacement of the solar ions with terrestrial ions, particularly O(+), which can have an average energy density of 3-4 keV/e at every activity level. The solar ions, however, increase in energy as their density decreases. The O(+) density is highest near the local midnight and becomes the most numerous during highly disturbed conditions. Finally, the O(+) density was observed to increase by a factor of three over the monitoring period, possibly due to enhanced solar EUV radiation.

  15. Plasma sheet stretching accompanied by field aligned energetic ion fluxes observed by the MUADU instrument aboard TC-2

    Institute of Scientific and Technical Information of China (English)

    Lu Li; S.MCKENNA-LAWLOR; S.BARABASH; LIU ZhenXing; CAO JinBin; J.BALAZ; K.KUDELA; T.L.ZHANG; C.M.CARR

    2007-01-01

    The NUADU(NeUtral Atom Detector Unit)instrument aboard TC-2 recorded 4π solid angle images of charged particles(E>180 keV)spiraling around the magnetic field lines in the near-Earth plasma sheet (at~-7 RE,equatorial dawn-to-night side)during a geomagnetic storm(Dst=-219 nT)on August 24,2005.Energetic ion beam events characterized by symmetrical,ring-like,solid angle distributions around ambient magnetic field lines were observed during a 34-minute traversal of the plasma sheet by the TC-2 spacecraft.Also,observations during these multiple crossings of the plasma sheet were monitored by the magnetometer experiment(FGM)aboard the same spacecraft.During each crossing,a whistler-mode chorus enhancement was observed in the anisotropic area by the TC-2 low frequency electromagnetic wave detector(LFEW/TC-2)at a frequency just above that of the local lower hybrid wave.A comparison of the ion pitch angle distribution(PAD)map with the ambient magnetic field shows that an enhancement in the field aligned energetic ion flux was accompanied by tailward stretching of the magnetic field lines in the plasma sheet.In contrast,the perpendicular ion-flux enhancement was accompanied by a signature indicating the corresponding shrinkage of the magnetic field lines in the plasma sheet.Since both parallel ion-flux and perpendicular ion-flux enhancements occurred intermittently,the data were interpreted to imply a dynamical,oscillatory process of the magnetic field line(stretching and shrinking)in the near-Earth plasma sheet,which might have acted to help establish an interaction region in this area which would support continuous aurora-substorm triggering during the ongoing magnetic storm.The whistler-mode chorus may have been produced due to ion gyro-resonance during particle pitch angle diffusion after the plasma sheet compression.

  16. Piezoresistive Effect in Plasma-Doping of Graphene Sheet for High-Performance Flexible Pressure Sensing Application.

    Science.gov (United States)

    Haniff, M A S M; Hafiz, S M; Huang, N M; Rahman, S A; Wahid, K A A; Syono, M I; Azid, I A

    2017-05-03

    This paper presents a straightforward plasma treatment modification of graphene with an enhanced piezoresistive effect for the realization of a high-performance pressure sensor. The changes in the graphene in terms of its morphology, structure, chemical composition, and electrical properties after the NH3/Ar plasma treatment were investigated in detail. Through a sufficient plasma treatment condition, our studies demonstrated that plasma-treated graphene sheet exhibits a significant increase in sensitivity by one order of magnitude compared to that of the unmodified graphene sheet. The plasma-doping introduced nitrogen (N) atoms inside the graphene structure and was found to play a significant role in enhancing the pressure sensing performance due to the tunneling behavior from the localized defects. The high sensitivity and good robustness demonstrated by the plasma-treated graphene sensor suggest a promising route for simple, low-cost, and ultrahigh resolution flexible sensors.

  17. A Theoretical Model of Pinching Current Sheet in Low-beta Plasmas

    CERN Document Server

    Takeshige, Satoshi; Shibata, Kazunari

    2015-01-01

    Magnetic reconnection is an important physical process in various explosive phenomena in the universe. In the previous studies, it was found that fast re- connection takes place when the thickness of a current sheet becomes on the order of a microscopic length such as the ion larmor radius or the ion inertial length. In this study, we investigated the pinching process of a current sheet by the Lorentz force in a low-{\\beta} plasma using one-dimensional magnetohydrodynam- ics (MHD) simulations. It is known that there is an exact self-similar solution for this problem that neglects gas pressure. We compared the non-linear MHD dynamics with the analytic self-similar solution. From the MHD simulations, we found that with the gas pressure included the implosion process deviates from the analytic self-similar solution as t {\\rightarrow} t 0, where t 0 is the explosion time when the thickness of a current sheet of the analytic solution becomes 0. We also found a pair of MHD fast-mode shocks are generated and propaga...

  18. An exact collisionless equilibrium for the Force-Free Harris Sheet with low plasma beta

    Energy Technology Data Exchange (ETDEWEB)

    Allanson, O., E-mail: oliver.allanson@st-andrews.ac.uk; Neukirch, T., E-mail: tn3@st-andrews.ac.uk; Wilson, F., E-mail: fw237@st-andrews.ac.uk; Troscheit, S., E-mail: s.troscheit@st-andrews.ac.uk [School of Mathematics and Statistics, University of St Andrews, St. Andrews, KY16 9SS (United Kingdom)

    2015-10-15

    We present a first discussion and analysis of the physical properties of a new exact collisionless equilibrium for a one-dimensional nonlinear force-free magnetic field, namely, the force-free Harris sheet. The solution allows any value of the plasma beta, and crucially below unity, which previous nonlinear force-free collisionless equilibria could not. The distribution function involves infinite series of Hermite polynomials in the canonical momenta, of which the important mathematical properties of convergence and non-negativity have recently been proven. Plots of the distribution function are presented for the plasma beta modestly below unity, and we compare the shape of the distribution function in two of the velocity directions to a Maxwellian distribution.

  19. An exact collisionless equilibrium for the Force-Free Harris Sheet with low plasma beta

    CERN Document Server

    Allanson, O; Wilson, F; Troscheit, S

    2015-01-01

    We present a first discussion and analysis of the physical properties of a new exact collisionless equilibrium for a one-dimensional nonlinear force-free magnetic field, namely the Force-Free Harris Sheet. The solution allows any value of the plasma beta, and crucially below unity, which previous nonlinear force-free collisionless equilibria could not. The distribution function involves infinite series of Hermite Polynomials in the canonical momenta, of which the important mathematical properties of convergence and non-negativity have recently been proven. Plots of the distribution function are presented for the plasma beta modestly below unity, and we compare the shape of the distribution function in two of the velocity directions to a Maxwellian distribution.

  20. Cluster view of the plasma sheet boundary layer and bursty bulk flow connection

    Directory of Open Access Journals (Sweden)

    O. W. Lennartsson

    2009-04-01

    Full Text Available The high-latitude boundaries of the plasma sheet (PSBL are dynamic latitude zones of recurring and transient (minutes to tens of minutes earthward and magnetic field-aligned bursts of plasma, each being more or less confined in longitude as well, whose ionic component is dominated by protons with flux, energies and density that are consistent with a central plasma sheet (CPS source at varying distance (varying rates of energy time dispersion, sometimes as close as the ~19 RE Cluster apogees, or closer still. The arguably most plausible source consists of so called "bursty bulk flows" (BBFs, i.e. proton bulk flow events with large, positive and bursty GSE vx. Known mainly from CPS observations made at GSE x>−30 RE, the BBF type events probably take place much further downtail as well. What makes the BBFs an especially plausible source are (1 their earthward bulk flow, which helps explain the lack of distinctive latitudinal PSBL energy dispersion, and (2 their association with a transient strong increase of the local tail Bz component ("local dipolarization". The enhanced Bz provides intermittent access to higher latitudes for the CPS plasma, resulting in local density reductions in the tail midplane, as illustrated here by proton data from the Cluster CIS CODIF instruments. Another sign of kinship between the PSBL bursts and the BBFs is their similar spatial fine structure. The PSBL bursts have prominent filaments aligned along the magnetic field with transverse flux gradients that are often characterized by local ~10 keV proton gyroradii scale size (or even smaller, as evidenced by Cluster measurements. The same kind of fine structure is also found during Cluster near-apogee traversals of the tail midplane, as illustrated here and implied by recently published statistics on BBFs obtained with Cluster multipoint observations at varying satellite

  1. Microfabrication of through holes in polydimethylsiloxane (PDMS) sheets using a laser plasma EUV source (Conference Presentation)

    Science.gov (United States)

    Makimura, Tetsuya; Urai, Hikari; Niino, Hiroyuki

    2017-03-01

    Polydimethylsiloxane (PDMS) is a material used for cell culture substrates / bio-chips and micro total analysis systems / lab-on-chips due to its flexibility, chemical / thermo-dynamic stability, bio-compatibility, transparency and moldability. For further development, it is inevitable to develop a technique to fabricate precise three dimensional structures on micrometer-scale at high aspect ratio. In the previous works, we reported a technique for high-quality micromachining of PDMS without chemical modification, by means of photo direct machining using laser plasma EUV sources. In the present work, we have investigated fabrication of through holes. The EUV radiations around 10 nm were generated by irradiation of Ta targets with Nd:YAG laser light (10 ns, 500 mJ/pulse). The generated EUV radiations were focused using an ellipsoidal mirror. It has a narrower incident angle than those in the previous works in order to form a EUV beam with higher directivity, so that higher aspect structures can be fabricated. The focused EUV beam was incident on PDMS sheets with a thickness of 15 micrometers, through holes in a contact mask placed on top of them. Using a contact mask with holes with a diameter of three micrometers, complete through holes with a diameter of two micrometers are fabricated in the PDMS sheet. Using a contact mask with two micrometer holes, however, ablation holes almost reaches to the back side of the PDMS sheet. The fabricated structures can be explained in terms of geometrical optics. Thus, we have developed a technique for micromachining of PDMS sheets at high aspect ratios.

  2. Collective dynamics of bursty particle precipitation initiating in the inner and outer plasma sheet

    Science.gov (United States)

    Uritsky, V. M.; Donovan, E.; Klimas, A. J.; Spanswick, E.

    2009-02-01

    Using multiscale spatiotemporal analysis of bursty precipitation events in the nighttime aurora as seen by the POLAR UVI instrument, we report a set of new statistical signatures of high- and low-latitude auroral activity, signaling a strongly non-uniform distribution of dissipation mechanism in the plasma sheet. We show that small-scale electron emission events that initiate in the equatorward portion of the nighttime auroral oval (scaling mode A1) have systematically steeper power-law slopes of energy, power, area, and lifetime probability distributions compared to the events that initiate at higher latitudes (mode B). The low-latitude group of events also contain a small but energetically important subpopulation of substorm-scale disturbances (mode A2) described by anomalously low distribution exponents characteristic of barely stable thermodynamic systems that are prone to large-scale sporadic reorganization. The high latitude events (mode organized critical (SOC) behavior. The low- and high latitude events have distinct inter-trigger time statistics, and are characterized by significantly different MLT distributions. Based on these results we conjecture that the inner and outer portions of the plasma sheet are associated with two (or more) mechanisms of collective dynamics that may represent an interplay between current disruption and magnetic reconnection scenarios of bursty energy conversion in the magnetotail.

  3. Multiple harmonic ULF waves in the plasma sheet boundary layer observed by Cluster

    Science.gov (United States)

    Engebretson, M. J.; Kahlstorf, C. R. G.; Posch, J. L.; Keiling, A.; Walsh, A. P.; Denton, R. E.; Broughton, M. C.; Owen, C. J.; FornaçOn, K.-H.; RèMe, H.

    2010-12-01

    The passage of the Cluster satellites in a polar orbit through Earth's magnetotail has provided numerous observations of harmonically related Pc 1-2 ULF wave events, with the fundamental near the local proton cyclotron frequency Ωcp. Broughton et al. (2008) reported observations by Cluster of three such events in the plasma sheet boundary layer, and used the wave telescope technique to determine that their wave vectors k were nearly perpendicular to B. This paper reports the results of a search for such waves throughout the 2003 Cluster tail passage. During the 4 month period of July-October 2003, 35 multiple-harmonic wave events were observed, all in the plasma sheet boundary layer (PSBL). From the first observed event (22 July) to the last (28 October), 13 of Cluster's 42 tail passes had at least one event. The wave events were rather evenly distributed from XGSE = -7 RE out to the Cluster apogee distance of -18 RE, with one event observed at -4 RE. ZGSE for these events ranged from -10 to -3 RE and +3 to +7 RE (i.e., there were no events for ∣Z∣ elevated fluxes of counterstreaming ions with energies ranging from ˜3 to 30 keV, and elevated fluxes of electrons with energies ranging from 0.25 to ˜5 keV. Analysis of plasma parameters suggests that although waves occurred only when the ion beta exceeded 0.1 (somewhat larger than typical for the PSBL), ion particle pressure may be of more physical importance in controlling wave occurrence. Electron distributions were more isotropic in pitch angles than the ion distributions, but some evidence of counterstreaming electrons was detected in 83% of the events. The ions also showed clear signatures of shell-like or ring-like distributions; i.e., with reduced fluxes below the energy of maximum flux. The suprathermal ion fluxes were asymmetric in all events studied, with more ions streaming earthward (for events both north and south of the central plasma sheet). Good agreement between the observed frequency of the

  4. Restructured graphene sheets embedded carbon film by oxygen plasma etching and its tribological properties

    Energy Technology Data Exchange (ETDEWEB)

    Guo, Meiling [Key Laboratory of Education Ministry for Modern Design and Rotor-Bearing System, School of Mechanical Engineering, Xi’an Jiaotong University, Xi’an 710049 (China); Diao, Dongfeng, E-mail: dfdiao@szu.edu.cn [Institute of Nanosurface Science and Engineering (INSE), Shenzhen University, Shenzhen 518060 (China); Yang, Lei [Key Laboratory of Education Ministry for Modern Design and Rotor-Bearing System, School of Mechanical Engineering, Xi’an Jiaotong University, Xi’an 710049 (China); Fan, Xue [Institute of Nanosurface Science and Engineering (INSE), Shenzhen University, Shenzhen 518060 (China)

    2015-12-01

    Highlights: • Oxygen plasma etching was developed to improve tribological properties of GSEC film. • Etching restructured 3 nm top layer with smaller crystallite size and higher sp{sup 3} fraction. • The etched film had smoother surface, enhanced mechanical properties, longer wear life. • High electrical conductivity and strong magnetism were retained after etching. - Abstract: An oxygen plasma etching technique was introduced for improving the tribological properties of the graphene sheets embedded carbon (GSEC) film in electron cyclotron resonance plasma processing system. The nanostructural changing in the film caused by oxygen plasma etching was examined by transmission electron microscope, Raman spectroscopy and X-ray photoelectron spectroscopy, showing that the 3 nm thick top surface layer was restructured with smaller graphene nanocrystallite size as well as higher sp{sup 3} bond fraction. The surface roughness, mechanical behavior and tribological properties of the original GSEC and oxygen plasma treated GSEC films were compared. The results indicated that after the oxygen plasma treatment, the average roughness decreased from 20.8 ± 1.1 nm to 1.9 ± 0.1 nm, the hardness increased from 2.3 ± 0.1 GPa to 2.9 ± 0.1 GPa, the nanoscratch depth decreased from 64.5 ± 5.4 nm to 9.9 ± 0.9 nm, and the wear life increased from 930 ± 390 cycles to more than 15,000 frictional cycles. The origin of the improved tribological behavior was ascribed to the 3 nm thick graphene nanocrystallite film. This finding can be expected for wide applications in nanoscale surface engineering.

  5. Studying the Important Relationship Between Earth's Plasma Sheet and the Outer Radiation Belt Electrons Using Newly Calibrated and Corrected Themis-Sst Data

    Science.gov (United States)

    Cruce, P. R.; Turner, D. L.; Angelopoulos, V.; Larson, D. E.; Shprits, Y.; Huang, C.; Ukhorskiy, A. Y.

    2011-12-01

    Most recently, the solid-state telescope (SST) data from the THEMIS mission, which consisted of 5 spacecraft in highly elliptic, equatorial orbits that have traversed the outer radiation belt and sampled the plasma sheet for more than 4 years, have been characterized, calibrated, and decontaminated. Here, we present a brief introduction on this corrected dataset and go into detail on the valuable resource it provides to address science questions concerning the important relationship between ~1 keV-10's keV electrons in the plasma sheet and 100's keV-MeV electrons in Earth's outer radiation belt. We demonstrate this by presenting preliminary results on: studying phase space density (PSD) radial gradients for fixed first and second adiabatic invariants from the radiation belt into the plasma sheet, examining pitch angle distributions near the boundary between these two regions, and studying the boundary region itself around the last closed drift shell and the role of magnetopause shadowing losses. We examine the dependence of PSD radial gradients on the first and second invariants to test previous results [e.g., Turner et al., GRL, 2008; Kim et al., JGR, 2010] that reveal mostly positive radial gradients for lower energy electrons (10's - couple hundred keV) but negative gradients for relativistic electrons beyond geosynchronous orbit. This directly relates to the current theory that lower energy electrons have a source in the plasma sheet and are introduced to the ring current and radiation belt via substorm injections and enhanced convection, and these particles then generate the waves necessary to accelerate a fraction of this seed population to relativistic energies, providing a source of the outer radiation belt. Next, we take advantage of the pitch angle resolved differential energy fluxes to examine variations in pitch angle distributions to establish the role that Shabansky drift orbits, which break electrons' second adiabatic invariant, play on outer belt

  6. Optimized H{sup -} extraction in an argon-magnesium seeded magnetized sheet plasma

    Energy Technology Data Exchange (ETDEWEB)

    Noguera, Virginia R. [Plasma Physics Laboratory, National Institute of Physics, University of the Philippines, Diliman, Quezon City 1101 (Philippines)], E-mail: virginia.noguera@gmail.com; Blantocas, Gene Q. [Plasma Physics Laboratory, National Institute of Physics, University of the Philippines, Diliman, Quezon City 1101 (Philippines); West Visayas State University, Lapaz, Iloilo City 5000 (Philippines); Ramos, Henry J. [Plasma Physics Laboratory, National Institute of Physics, University of the Philippines, Diliman, Quezon City 1101 (Philippines)

    2008-06-15

    The enhancement and optimization of H{sup -} extraction through argon and magnesium seeding of hydrogen discharges in a magnetized sheet plasma source are reported. The paper first presents the modification of the production chamber into a hexapole multicusp configuration resulting in decreased power requirements, improved plasma confinement and longer filament lifetime. By this, a wider choice of discharge currents for sustained quiescent plasmas is made possible. Second, the method of adding argon to the hydrogen plasma similar to the scheme in Abate and Ramos [Y. Abate, H. Ramos, Rev. Sci. Instr. 71 (10) (2000) 3689] was performed to find the optimum conditions for H{sup -} formation and extraction. Using an E x B probe, H{sup -} yields were investigated at varied argon-hydrogen admixtures, different discharge currents and spatial points relative to the core plasma. The optimum H{sup -} current density extracted at 3.0 cm from the plasma core using 3.0 A plasma current with 10% argon seeding increased by a factor of 2.42 (0.63 A/m{sup 2}) compared to the measurement of Abate and Ramos [Y. Abate, H. Ramos, Rev. Sci. Instr. 71 (10) (2000) 3689]. Third, the argon-hydrogen plasma at the extraction chamber is seeded with magnesium. Mg disk with an effective area of 22 cm{sup 2} is placed at the extraction region's anode biased 175 V with respect to the cathode. With Mg seeding, the optimum H{sup -} current density at the same site and discharge conditions increased by 4.9 times (3.09 A/m{sup 2}). The enhancement effects were analyzed vis-a-vis information gathered from the usual Langmuir probe (electron temperature and density), electron energy distribution function (EEDF) and the ensuing dissociative attachment (DA) reaction rates at different spatial points for various plasma discharges and gas ratios. Investigations on the changes in the effective electron temperature and electron density indicate that the enhancement is due to increased density of low

  7. O+ ion conic and plasma sheet dynamics observed by Van Allen Probe satellites during the 1 June 2013 magnetic storm

    Science.gov (United States)

    Burke, W. J.; Erickson, P. J.; Yang, J.; Foster, J.; Wygant, J.; Reeves, G.; Kletzing, C.

    2016-05-01

    The Van Allen Probe satellites were near apogee in the late evening local time sector during the 1 June 2013 magnetic storm's main phase. About an hour after crossing the ring current's "nose structure" into the plasma sheet, the satellites encountered a quasiperiodic sequence of 0.08-3 keV O+ ions. Pitch angle distributions of this population consistently peaked nearly antiparallel to the local magnetic field. We interpret this population as O+ conics originating in the northern ionosphere. Sequences began as fairly steady state conic fluxes with energies in the ~ 80 to 100 eV range. Over about a half hour buildup phase, O+ energies peaked near 1 keV. During subsequent release phases lasting ~ 20 min, O+ energies returned to low-energy starting points. We argue these observations reflect repeated formations and dissolutions of downward, magnetically aligned electric fields (ɛ||) layers trapping O+ conics between mirror points within heating layers below and electrostatic barriers above. Nearly identical variations were observed at the locations of both satellites during 9 of these 13 conic cycles. Phase differences between cycles were observed at both spacecraft during the remaining events. Most "buildup" to "release" phase transitions coincided with AL index minima. However, in situ magnetometer measurements indicate only weak dipolarizations of tail-like magnetic fields. The lack of field-aligned reflected O+ and tail-like magnetic fields suggest that both ionospheres may be active. However, Southern Hemisphere origin conics cannot be observed since they would be isotropized and accelerated during neutral sheet crossings.

  8. Anisotropic Equilibrium and Ballooning Mode Analysis in the Tail Plasma Sheet.

    Science.gov (United States)

    Lee, Dae-Young

    This thesis is a theoretical study about the Earth's tail plasma sheet with regard to two aspects: the equilibrium structure for the anisotropic pressure, and the ideal-MHD ballooning stability. By adopting a stretched magnetotail model where ion motions are generally nonadiabatic, and assuming that the anisotropy resides only in the electron pressure tensor, it is shown that the magnetic field lines with rm p_| > p_| are less stretched than the isotropic cases. As the parallel pressure p_| exceeds the perpendicular pressure p_| approaching the conventional marginal firehose limit, rm p_| = p{_ |} + B^2/ mu_0, the magnetic field lines are more and more stretched. It is also shown that the current density is highly enhanced at the same limit, a situation that might be subject to a microscopic instability. However, we also emphasize that such an enhancement in the current density is heavily localized near the z = 0 plane, and thus it is unclear if such a microscopic instability can significantly alter the global configuration of the tail. It is further argued, in terms of the radius of the field curvature versus the particle's gyroradius, that the conventional adiabatic description of electrons may become questionable, very close to the conventional marginal firehose limit. To study the ideal-MHD ballooning mode, we first adopt a hard ionospheric boundary condition where the perturbation is required to vanish at the ionospheric foot points. For such a hard boundary condition, an "untypical" magnetic field configuration is found to be unstable to a ballooning mode that is antisymmetric about the equatorial plane while most of the "typical" tail plasma-sheet configurations are stable against the ideal-MHD ballooning mode. The unstable magnetic field model, however, does not look like the average observation-based model, but rather resembles some of the characteristics of the steady-state magnetic field models by Hau (1989, 1991). In addition, a physical argument is

  9. Influence of the initial parameters of the magnetic field and plasma on the spatial structure of the electric current and electron density in current sheets formed in helium

    Energy Technology Data Exchange (ETDEWEB)

    Ostrovskaya, G. V., E-mail: galya-ostr@mail.ru [Russian Academy of Sciences, Ioffe Physical Technical Institute (Russian Federation); Markov, V. S.; Frank, A. G., E-mail: annfrank@fpl.gpi.ru [Russian Academy of Sciences, Prokhorov General Physics Institute (Russian Federation)

    2016-01-15

    The influence of the initial parameters of the magnetic field and plasma on the spatial structure of the electric current and electron density in current sheets formed in helium plasma in 2D and 3D magnetic configurations with X-type singular lines is studied by the methods of holographic interferometry and magnetic measurements. Significant differences in the structures of plasma and current sheets formed at close parameters of the initial plasma and similar configurations of the initial magnetic fields are revealed.

  10. ISEE-3 observations of a viscously-driven plasma sheet: magnetosheath mass and/or momentum transfer?

    Directory of Open Access Journals (Sweden)

    R. T. Mist

    Full Text Available A statistical analysis of data from the ISEE-3 distant tail campaign is presented. We investigate the mechanism driving slow, tailward flows observed in the plasma sheet. The possibility that these slow flows are driven by mass and/or momentum transfer across the distant tail magnetopause is explored. We establish that 40% of these flows could be driven by the transfer of approximately 4% of the magnetosheath momentum flux into the magnetotail. Current understanding of the Kelvin-Helmholtz instability suggests that this figure is consistent with the amount of momentum flux transfer produced by this mechanism. We also consider the possibility that these flows are solely driven by transferring magnetosheath plasma across the magnetopause. We find that there is sufficient mass observed on these field lines for this to be the sole driving mechanism for only 27% of the observed slow flows.

    Key words. Magnetospheric physics (magnetotail boundary layers; plasma convection; plasma sheet

  11. Origin of low proton-to-electron temperature ratio in the Earth's plasma sheet

    Science.gov (United States)

    Grigorenko, E. E.; Kronberg, E. A.; Daly, P. W.; Ganushkina, N. Yu.; Lavraud, B.; Sauvaud, J.-A.; Zelenyi, L. M.

    2016-10-01

    We study the proton-to-electron temperature ratio (Tp/Te) in the plasma sheet (PS) of the Earth's magnetotail using 5 years of Cluster observations (2001-2005). The PS intervals are searched within a region defined with -19 GSM) under the condition |BX| ≤ 10 nT. One hundred sixty PS crossings are identified. We find an average value of 6.0. However, in many PS intervals Tp/Te varies over a wide range from a few units to several tens of units. In 86 PS intervals the Tp/Te decreases below 3.5. Generally, the decreases of Tp/Te are due to some increase of Te while Tp either decreases or remains unchanged. In the majority of these intervals the Tp/Te drops are observed during magnetotail dipolarizations. A superposed epoch analysis applied to these events shows that the minimum value of Tp/Te is observed after the dipolarization onset during the "turbulent phase" of dipolarization, when a number of transient BZ pulses are reduced, but the value of BZ is still large and an intensification of wave activity is observed. The Tp/Te drops, and associated increases of Te often coincide either with bursts of broadband electrostatic emissions, which may include electron cyclotron harmonics, or with broadband electromagnetic emission in a frequency range from proton plasma frequency (fpp) up to the electron gyrofrequency (fce). These findings show that the wave activity developing in the current sheet after dipolarization onset may play a role in the additional electron heating and the associated Tp/Te decrease.

  12. Long-term variations in the plasma sheet ion composition and substorm occurrence over 23 years

    Science.gov (United States)

    Nosé, Masahito

    2016-12-01

    The Geotail satellite has been operating for almost two solar cycles (~23 years) since its launch in July 1992. The satellite carries the energetic particle and ion composition (EPIC) instrument that measures the energetic ion flux (9.4-212 keV/e) and enables the investigation of long-term variations of the ion composition in the plasma sheet for solar cycles 22-24. From the statistical analysis of the EPIC data, we find that (1) the plasma ion mass ( M) is approximately 1.1 amu during the solar minimum, whereas it increases to 1.5-2.7 amu during the solar maximum; (2) the increases in M seem to have two components: a raising of the baseline levels (~1.5 amu) and a large transient enhancement (~1.8-2.7 amu); (3) the baseline level change of M correlates well with the Mg II index, which is a good proxy for the solar extreme ultraviolet (EUV) or far ultraviolet (FUV) irradiance; and (4) the large transient enhancement of M is caused by strong magnetic storms. We also study the long-term variations of substorm occurrences in 1992-2015 that are evaluated with the number of Pi2 pulsations detected at the Kakioka observatory. The results suggest no clear correlation between the substorm occurrence and the Mg II index. Instead, when the substorms are classified into externally triggered events and non-triggered events, the number of the non-triggered events and the Mg II index are negatively correlated. We interpret these results that the increase in the solar EUV/FUV radiation enhances the supply of ionospheric ions (He+ and O+ ions) into the plasma sheet to increase M, and the large M may suppress spontaneous plasma instabilities initiating substorms and decrease the number of the non-triggered substorms. The present analysis using the unprecedentedly long-term dataset covering ~23 years provides additional observational evidence that heavy ions work to prevent the occurrence of substorms.

  13. The evaluation of surface and adhesive bonding properties for cold rolled steel sheet for automotive treated by Ar/O{sub 2} atmospheric pressure plasma

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Chan Joo; Lee, Sang Kon; Kim Byung Min [Pusan National University, Busan (Korea, Republic of); Park, Keun Whan [Sungwoo Hitech Technical Institute, Busan (Korea, Republic of)

    2008-04-15

    Cold rolled steel sheet for automotive was treated by Ar/O{sub 2} atmospheric pressure plasma to improve the adhesive bonding strength. Through the contact angle test and calculation of surface free energy for cold rolled steel sheet, the changes of surface properties were investigated before and after plasma treatment. The contact angle was decreased and surface free energy was increased after plasma treatment. And the change of surface roughness and morphology were observed by AFM(Atomic Force Microscope). The surface roughness of steel sheet was slightly changed. Based on Taguchi method, single lap shear test was performed to investigate the effect of experimental parameter such as plasma power, treatment time and flow rate of O{sub 2} gas. Results shows that the bonding strength of steel sheet treated in Ar/O{sub 2} atmospheric pressure plasma was improved about 20% compared with untreated sheet.

  14. Plasmoid ejection and secondary current sheet generation from magnetic reconnection in laser-plasma interaction.

    Science.gov (United States)

    Dong, Quan-Li; Wang, Shou-Jun; Lu, Quan-Ming; Huang, Can; Yuan, Da-Wei; Liu, Xun; Lin, Xiao-Xuan; Li, Yu-Tong; Wei, Hui-Gang; Zhong, Jia-Yong; Shi, Jian-Rong; Jiang, Shao-En; Ding, Yong-Kun; Jiang, Bo-Bin; Du, Kai; He, Xian-Tu; Yu, M Y; Liu, C S; Wang, Shui; Tang, Yong-Jian; Zhu, Jian-Qiang; Zhao, Gang; Sheng, Zheng-Ming; Zhang, Jie

    2012-05-25

    Reconnection of the self-generated magnetic fields in laser-plasma interaction was first investigated experimentally by Nilson et al. [Phys. Rev. Lett. 97, 255001 (2006)] by shining two laser pulses a distance apart on a solid target layer. An elongated current sheet (CS) was observed in the plasma between the two laser spots. In order to more closely model magnetotail reconnection, here two side-by-side thin target layers, instead of a single one, are used. It is found that at one end of the elongated CS a fanlike electron outflow region including three well-collimated electron jets appears. The (>1 MeV) tail of the jet energy distribution exhibits a power-law scaling. The enhanced electron acceleration is attributed to the intense inductive electric field in the narrow electron dominated reconnection region, as well as additional acceleration as they are trapped inside the rapidly moving plasmoid formed in and ejected from the CS. The ejection also induces a secondary CS.

  15. CO2 laser-micro plasma arc hybrid welding for galvanized steel sheets

    Institute of Scientific and Technical Information of China (English)

    C. H. KIM; Y. N. AHN; J. H. KIM

    2011-01-01

    A laser lap welding process for zinc-coated steel has a well-known unsolved problem-porosity formation. The boiling temperature of coated zinc is lower than the melting temperature of the base metal. which is steel. In the autogenous laser welding,the zinc vapor generates from the lapped surfaces expels the molten pool and the expulsion causes numerous weld defects, such as spatters and blow holes on the weld surface and porosity inside the welds. The laser-arc hybrid welding was suggested as an alternative method for the laser lap welding because the arc can preheat or post-heat the weldment according to the arrangement of the laser beam and the arc. CO2 laser-micro plasma hybrid welding was applied to the lap welding of zinc-coated steel with zero-gap.The relationships among the weld quality and process parameters of the laser-arc arrangement, and the laser-arc interspacing distance and arc current were investigated using a full-factorial experimental design. The effect of laser-arc arrangement is dominant because the leading plasma arc partially melts the upper steel sheets and vaporizes or oxidizes the coated zinc on the lapped surfaces.Compared with the result from the laser-TIG hybrid welding, the heat input from arc can be reduced by 40%.

  16. Fractal Structure of the Heliospheric Plasma Sheet at the Earth's Orbit

    Institute of Scientific and Technical Information of China (English)

    M. V. Eselevich; V. G. Eselevich

    2005-01-01

    An analysis of the data from the Wind and IMP-8 spacecraft revealed that a slow solar wind,flowing in the heliospheric plasma sheet, represents a set of magnetic tubes with plasma of increased density(N > 10cm-3 at the Earth's orbit). They have a fine structure at several spatial scales (fractality), from2°-3° (at the Earth's orbit, it is equivalent to 3.6-5.4 h, or(5.4-8.0) × 106 km) to the minimum about0.025°, i.e. the angular siz.e of the nested tubes is changed nearly by two orders of magnitude. The magnetic tubes at each observed spatial scale are diamagnetic, i.e. their surface sustains a flow of diamagnetic (or drift)current that decreases the magnetic field within the tube itself and increases it outside the tube. Furthermore,the value of β = 8π[N(Te + Tp)]/B2 within the tube exceeds the value of β outside the tube. In many cases total pressure P = N(Te + Tp) + B2/8π is almost constant within and outside the tubes at any one of the aforementioned scales.

  17. Multiple harmonic ULF waves in the plasma sheet boundary layer: Instability analysis

    Science.gov (United States)

    Denton, R. E.; Engebretson, M. J.; Keiling, A.; Walsh, A. P.; Gary, S. P.; DéCréAu, P. M. E.; Cattell, C. A.; RèMe, H.

    2010-12-01

    Multiple-harmonic electromagnetic waves in the ULF band have occasionally been observed in Earth's magnetosphere, both near the magnetic equator in the outer plasmasphere and in the plasma sheet boundary layer (PSBL) in Earth's magnetotail. Observations by the Cluster spacecraft of multiple-harmonic electromagnetic waves with fundamental frequency near the local proton cyclotron frequency, Ωcp, were recently reported in the plasma sheet boundary layer by Broughton et al. (2008). A companion paper surveys the entire magnetotail passage of Cluster during 2003, and reports 35 such events, all in the PSBL, and all associated with elevated fluxes of counterstreaming ions and electrons. In this study we use observed pitch angle distributions of ions and electrons during a wave event observed by Cluster on 9 September 2003 to perform an instability analysis. We use a semiautomatic procedure for developing model distributions composed of bi-Maxwellian components that minimizes the difference between modeled and observed distribution functions. Analysis of wave instability using the WHAMP electromagnetic plasma wave dispersion code and these model distributions reveals an instability near Ωcp and its harmonics. The observed and model ion distributions exhibit both beam-like and ring-like features which might lead to instability. Further instability analysis with simple beam-like and ring-like model distribution functions indicates that the instability is due to the ring-like feature. Our analysis indicates that this instability persists over an enormous range in the effective ion beta (based on a best fit for the observed distribution function using a single Maxwellian distribution), β', but that the character of the instability changes with β'. For β' of order unity (for instance, the observed case with β' ˜ 0.4), the instability is predominantly electromagnetic; the fluctuating magnetic field has components in both the perpendicular and parallel directions, but the

  18. Ion shell distributions as free energy source for plasma waves on auroral field lines mapping to plasma sheet boundary layer

    Directory of Open Access Journals (Sweden)

    A. Olsson

    2004-06-01

    Full Text Available Ion shell distributions are hollow spherical shells in velocity space that can be formed by many processes and occur in several regions of geospace. They are interesting because they have free energy that can, in principle, be transmitted to ions and electrons. Recently, a technique has been developed to estimate the original free energy available in shell distributions from in-situ data, where some of the energy has already been lost (or consumed. We report a systematic survey of three years of data from the Polar satellite. We present an estimate of the free energy available from ion shell distributions on auroral field lines sampled by the Polar satellite below 6 RE geocentric radius. At these altitudes the type of ion shells that we are especially interested in is most common on auroral field lines close to the polar cap (i.e. field lines mapping to the plasma sheet boundary layer, PSBL. Our analysis shows that ion shell distributions that have lost some of their free energy are commonly found not only in the PSBL, but also on auroral field lines mapping to the boundary plasma sheet (BPS, especially in the evening sector auroral field lines. We suggest that the PSBL ion shell distributions are formed during the so-called Velocity Dispersed Ion Signatures (VDIS events. Furthermore, we find that the partly consumed shells often occur in association with enhanced wave activity and middle-energy electron anisotropies. The maximum downward ion energy flux associated with a shell distribution is often 10mWm-2 and sometimes exceeds 40mWm-2 when mapped to the ionosphere and thus may be enough to power many auroral processes. Earlier simulation studies have shown that ion shell distributions can excite ion Bernstein waves which, in turn, energise electrons in the parallel direction. It is possible that ion shell distributions are the link between the X-line and the auroral wave activity and electron

  19. Controllable formation of graphene and graphene oxide sheets using photo-catalytic reduction and oxygen plasma treatment

    Science.gov (United States)

    Ostovari, Fatemeh; Abdi, Yaser; Ghasemi, Foad

    2012-12-01

    Au/SiO2/Si interdigital electrodes with thickness of 1 μm were created on silicon substrate. Graphene oxide (GO) sheets hanging from these electrodes were obtained by spin coating of chemically synthesized GO dispersed in water. We used UV-light-induced photo-catalytic activity of titanium oxide nanoparticles to reduce the GO layer. Effects of the photo-induced chemical reduction on the conductivity of the GO were investigated. Also, low power DC plasma was used for oxidation of the sheets. Oxygen bombardment leads to sheets with low electrical conductivity. Measurements show that graphene and GO sheets with the controlled electrical conductivity were obtained by these processes. Scanning electron and atomic force microscopy were used to study the morphology of the TiO2/GO and graphene structures. X-ray diffraction and Raman scattering analysis were used to verify the structural characteristics of the prepared sheets. Analysis showed a gradual increase in the number of C-O bonds on the surface of the graphene layer as a result of increasing the time of plasma bombardment. Based on the Raman spectroscopy, the photo-catalytic activity of TiO2 nanoparticles resulted in a decrease in the number of C-O bonds.

  20. New types of coating systems for steel sheets by high-rate evaporation in combination with plasma processes

    Energy Technology Data Exchange (ETDEWEB)

    Scheffel, B.; Metzner, C. [Fraunhofer-Institut fuer Elektronenstrahl und Plasmatechnik (FEP), Dresden (Germany); Ehlers, K.D. [Salzgitter AG Stahl und Technologie (Germany); Schuhmacher, B. [Dortmunder Oberflaechencentrum GmbH, Dortmund (Germany); Flossdorf, F.J.; Steinbeck, G. [Verein Deutscher Eisenhuettenleute (VDEh), Duesseldorf (Germany); Steffen, R. [Stahlwerke Bremen GmbH (Germany); Hagler, J. [voestalpine Stahl GmbH, Linz (Austria)

    2002-03-01

    High-rate evaporation in combination with plasma processes is a promising approach to obtain new types of steel sheet coating with improved corrosion resistance and application properties. To estimate the potential for the application of PVD-coatings (physical vapour deposition) different coating systems for steel sheet as well as for hot-dip or electro-galvanized steel sheet were designed. The samples were produced on a laboratory scale using PVD processes with very high deposition rates (in the order of 1 {mu}m s{sup -1}) as well as high-power plasma processes for the pre-treatment. The relationship between the composition, microstructure and properties of the coating systems, in particular concerning corrosion protection, abrasion during forming, phosphating and paint adhesion, were studied. It was found that the corrosion resistance of galvanized steel sheets can be considerably improved by vapour deposition of metal or inorganic films with a thickness of several hundred nanometers. Investigations on vapour deposition of titanium and stainless steel coatings on steel sheets, for applications in a severely corrosive environment, showed that the corrosion resistance in relation to the coating thickness can be significantly enhanced by means of plasma activation during the vapour deposition process. Finally, an outlook on possible industrial applications including an estimation of the process costs will be presented. For certain coating systems the results look promising. Consequently, these particular coating systems will be investigated in more detail by means of using a large-scale in-line deposition plant for metallic strips and sheets. (orig.)

  1. Modeling the Self-organized Critical Behavior of the Plasma Sheet Reconnection Dynamics

    Science.gov (United States)

    Klimas, Alex; Uritsky, Vadim; Baker, Daniel

    2006-01-01

    Analyses of Polar UVI auroral image data reviewed in our other presentation at this meeting (V. Uritsky, A. Klimas) show that bright night-side high-latitude UV emissions exhibit so many of the key properties of systems in self-organized criticality (SOC) that an alternate interpretation has become virtually impossible. It is now necessary to find and model the source of this behavior. We note that the most common models of self-organized criticality are numerical sandpiles. These are, at root, models that govern the transport of some quantity from a region where it is loaded to another where it is unloaded. Transport is enabled by the excitation of a local threshold instability; it is intermittent and bursty, and it exhibits a number of scale-free statistical properties. Searching for a system in the magnetosphere that is analogous and that, in addition, is known to produce auroral signatures, we focus on the reconnection dynamics of the plasma sheet. In our previous work, a driven reconnection model has been constructed and has been under study. The transport of electromagnetic (primarily magnetic) energy carried by the Poynting flux into the reconnection region of the model has been examined. All of the analysis techniques, and more, that have been applied to the auroral image data have also been applied to this Poynting flux. Here, we report new results showing that this model also exhibits so many of the key properties of systems in self-organized criticality that an alternate interpretation is implausible. Further, we find a strong correlation between these key properties of the model and those of the auroral UV emissions. We suggest that, in general, the driven reconnection model is an important step toward a realistic plasma physical model of self-organized criticality and we conclude, more specifically, that it is also a step in the right direction toward modeling the multiscale reconnection dynamics of the magnetotail.

  2. Modeling the Self-organized Critical Behavior of Earth's Plasma Sheet Reconnection Dynamics

    Science.gov (United States)

    Klimas, Alexander J.

    2006-01-01

    Analyses of Polar UVI auroral image data show that bright night-side high-latitude W emissions exhibit so many of the key properties of systems in self-organized criticality that an alternate interpretation has become virtually impossible. These analyses will be reviewed. It is now necessary to find and model the source of this behavior. We note that the most common models of self-organized criticality are numerical sandpiles. These are, at root, models that govern the transport of some quantity from a region where it is loaded to another where it is unloaded. Transport is enabled by the excitation of a local threshold instability; it is intermittent and bursty, and it exhibits a number of scale-free statistical properties. Searching for a system in the magnetosphere that is analogous and that, in addition, is known to produce auroral signatures, we focus on the reconnection dynamics of the magnetotail plasma sheet. In our previous work, a driven reconnection model has been constructed and has been under study. The transport of electromagnetic (primarily magnetic) energy carried by the Poynting flux into the reconnection region of the model has been examined. All of the analysis techniques (and more) that have been applied to the auroral image data have also been applied to this Poynting flux. New results will be presented showing that this model also exhibits so many of the key properties of systems in self-organized criticality that an alternate interpretation is implausible. A strong correlation between these key properties of the model and those of the auroral UV emissions will be demonstrated. We suggest that, in general, the driven reconnection model is an important step toward a realistic plasma physical model of self-organized criticality and we conclude, more specifically, that it is also a step in the right direction toward modeling the multiscale reconnection dynamics of the magnetotail.

  3. Shock wave interaction with a thermal layer produced by a plasma sheet actuator

    Science.gov (United States)

    Koroteeva, E.; Znamenskaya, I.; Orlov, D.; Sysoev, N.

    2017-03-01

    This paper explores the phenomena associated with pulsed discharge energy deposition in the near-surface gas layer in front of a shock wave from the flow control perspective. The energy is deposited in 200 ns by a high-current distributed sliding discharge of a ‘plasma sheet’ type. The discharge, covering an area of 100× 30 mm2, is mounted on the top or bottom wall of a shock tube channel. In order to analyse the time scales of the pulsed discharge effect on an unsteady supersonic flow, we consider the propagation of a planar shock wave along the discharge surface area 50–500 μs after the discharge pulse. The processes in the discharge chamber are visualized experimentally using the shadowgraph method and modelled numerically using 2D/3D CFD simulations. The interaction between the planar shock wave and the discharge-induced thermal layer results in the formation of a lambda-shock configuration and the generation of vorticity in the flow behind the shock front. We determine the amount and spatial distribution of the electric energy rapidly transforming into heat by comparing the calculated flow patterns and the experimental shadow images. It is shown that the uniformity of the discharge energy distribution strongly affects the resulting flow dynamics. Regions of turbulent mixing in the near-surface gas are detected when the discharge energy is deposited non-uniformly along the plasma sheet. They account for the increase in the cooling rate of the discharge-induced thermal layer and significantly influence its interaction with an incident shock wave.

  4. Modeling the effect of doping on the catalyst-assisted growth and field emission properties of plasma-grown graphene sheet

    Energy Technology Data Exchange (ETDEWEB)

    Gupta, Neha; Sharma, Suresh C.; Sharma, Rinku [Department of Applied Physics, Delhi Technological University (DTU), Shahbad Daulatpur, Bawana Road, Delhi-110042 (India)

    2016-08-15

    A theoretical model describing the effect of doping on the plasma-assisted catalytic growth of graphene sheet has been developed. The model accounts the charging rate of the graphene sheet, kinetics of all the plasma species, including the doping species, and the growth rate of graphene nuclei and graphene sheet due to surface diffusion, and accretion of ions on the catalyst nanoparticle. Using the model, it is observed that nitrogen and boron doping can strongly influence the growth and field emission properties of the graphene sheet. The results of the present investigation indicate that nitrogen doping results in reduced thickness and shortened height of the graphene sheet; however, boron doping increases the thickness and height of the graphene sheet. The time evolutions of the charge on the graphene sheet and hydrocarbon number density for nitrogen and boron doped graphene sheet have also been examined. The field emission properties of the graphene sheet have been proposed on the basis of the results obtained. It is concluded that nitrogen doped graphene sheet exhibits better field emission characteristics as compared to undoped and boron doped graphene sheet. The results of the present investigation are consistent with the existing experimental observations.

  5. A feature of negative hydrogen ion production in the Uramoto-type sheet plasma

    Energy Technology Data Exchange (ETDEWEB)

    Jimbo, Kouichi [Kyoto Univ., Uji (Japan). Inst. of Atomic Energy

    1997-02-01

    It seems that negative hydrogen ions H{sup -} are formed directly from atomic hydrogens H. When the chamber was biased more negative against the anode potential at constant are power, forming a much deeper electrostatic well in the Uramoto-type sheet plasma negative ion source, more negative hydrogen ion currents were extracted. The chamber potential V{sub B} was biased down to -100V in the 150V discharge. The negative ion current J{sup -} was evaluated by the JAERI-probe measurement. J{sup -} increases linearly with the chamber current I{sub B}. The largest J{sup -} value was obtained at absolute value of |V{sub prob,f}|=15V and absolute value of |V{sub B}|=100V; the discharge was not operated for absolute value of |V{sub B}|>100V. We speculate the following collisional (three-body) electron attachment to H as a possible production process for H{sup -}; e+e+H{yields}e+H{sup -}. This process may explain the linear increase of J{sup -} with absolute value of |V{sub prob,f}|. (S.Y.)

  6. Study of kinetic Alfven wave (KAW) in plasma - sheet-boundary- layer

    Energy Technology Data Exchange (ETDEWEB)

    Shukla, Nidhi; Varma, P; Tiwari, M S, E-mail: tiwarims@rediffmail.co, E-mail: poornimavarma@yahoo.co, E-mail: nidhiphy.shukla@gmail.co [Department of Physics and Electronics, Dr. H. S. Gour University, Sagar (M.P.), 470003 (India)

    2010-02-01

    The effect of parallel electric field with general loss-cone distribution function on the dispersion relation and damping rate/growth rate of the kinetic Alfven wave (KAW) is evaluated by kinetic approach. The generation of KAW by the combined effect of parallel electric field and loss-cone distribution indices (J) at a particular range of k{sub p}erpendicular{rho}{sub i} (k{sub p}erpendicular{rho}{sub i} <1 and k{sub p}erpendicular{rho}{sub i} >1) is noticed, where k{sub p}erpendicular is perpendicular wave number and {rho}{sub i} is the ion-gyro radius. Thus the propagation of KAW and loss of the Poynting flux from plasma sheet boundary layer (PSBL) to the ionosphere can be explained on the basis of present investigation. It is found that the present study also shows that the loss-cone distribution index is an important parameter to study KAW in the PSBL.

  7. Field-aligned currents observed by MMS in the near-Earth plasma sheet during large-scale substorm dipolarizations.

    Science.gov (United States)

    Nakamura, Rumi; Nagai, Tsugunobu; Giles, Barbara; Le Contel, Olivier; Stawarz, Julia; Khotyaintsev, Yuri; Artemyev, Anton

    2017-04-01

    During substorms significant energy conversion has been reported to take place at the sharp dipolarization front in the flow braking region where the probability of observing bursty bulk flows (BBFs) significantly drops. On 10 August 2016, MMS traversed the pre-midnight near-Earth plasma sheet when dipolarization disturbances were detected in an extended nightside local time region by Cluster, Geotail, GOES 13, 14 and 15, and the Van Allen Probes. In an expanding plasma sheet during the dipolarization, MMS detected sub-ion scale field-aligned current layers that are propagating both Earthward (equatorward) as well as tailward (outward). These multi-scale multi-point observations enable a unique investigation of both the meso-scale evolution of the disturbances and the detailed kinetic structures of the fronts and boundaries relevant to the dipolarizations.

  8. ISEE-3 observations of a viscously-driven plasma sheet: magnetosheath mass and/or momentum transfer?

    OpenAIRE

    Mist, R. T.; Owen, C.J.

    2002-01-01

    A statistical analysis of data from the ISEE-3 distant tail campaign is presented. We investigate the mechanism driving slow, tailward flows observed in the plasma sheet. The possibility that these slow flows are driven by mass and/or momentum transfer across the distant tail magnetopause is explored. We establish that 40% of these flows could be driven by the transfer of approximately 4% of the magnetosheath momentum flux into the magnetotail. Current understanding of the Kelvin-Helmholtz in...

  9. ISEE-3 observations of a viscously-driven plasma sheet: magnetosheath mass and/or momentum transfer?

    OpenAIRE

    Mist, R. T.; Owen, C.J.

    2002-01-01

    A statistical analysis of data from the ISEE-3 distant tail campaign is presented. We investigate the mechanism driving slow, tailward flows observed in the plasma sheet. The possibility that these slow flows are driven by mass and/or momentum transfer across the distant tail magnetopause is explored. We establish that 40% of these flows could be driven by the transfer of approximately 4% of the magnetosheath momentum flux into the magnetotail. Current understanding of the Kelvin-Helmh...

  10. Plasma arc brazing - a low energy joining technology for steel sheets; Plasmalichtbogenloeten - eine energiearme Fuegetechnik fuer Feinblechwerkstoffe

    Energy Technology Data Exchange (ETDEWEB)

    Bouaifi, B.; Draugelates, U.; Helmich, A.; Ouaissa, B. [TU Clausthal, Clausthal-Zellerfeld (Germany)

    2001-07-01

    Mild and high strength steel sheets are comparatively difficult to weld. The heat input in the case of conventional welding processes is too high, so that plasma brazing is an attractive alternative and complementary joining process. One characteristic of the process is the independent input of energy and filler material. In addition, the process is practically spatter-free. Plasma brazing reduces joint and panel distortion and is tolerant to surface contamination and metallic surface coatings. The brazed seams are aesthetic in appearance and clear good mechanical properties. (orig.)

  11. Experimental study of nonlinear interaction of plasma flow with charged thin current sheets: 1. Boundary structure and motion

    Directory of Open Access Journals (Sweden)

    E. Amata

    2006-01-01

    Full Text Available We study plasma transport at a thin magnetopause (MP, described hereafter as a thin current sheet (TCS, observed by Cluster at the southern cusp on 13 February 2001 around 20:01 UT. The Cluster observations generally agree with the predictions of the Gas Dynamic Convection Field (GDCF model in the magnetosheath (MSH up to the MSH boundary layer, where significant differences are seen. We find for the MP a normal roughly along the GSE x-axis, which implies a clear departure from the local average MP normal, a ~90 km thickness and an outward speed of 35 km/s. Two populations are identified in the MSH boundary layer: the first one roughly perpendicular to the MSH magnetic field, which we interpret as the "incident" MSH plasma, the second one mostly parallel to B. Just after the MP crossing a velocity jet is observed with a peak speed of 240 km/s, perpendicular to B, with MA=3 and β>10 (peak value 23. The magnetic field clock angle rotates by 70° across the MP. Ex is the main electric field component on both sides of the MP, displaying a bipolar signature, positive on the MSH side and negative on the opposite side, corresponding to a ~300 V electric potential jump across the TCS. The E×B velocity generally coincides with the perpendicular velocity measured by CIS; however, in the speed jet a difference between the two is observed, which suggests the need for an extra flow source. We propose that the MP TCS can act locally as an obstacle for low-energy ions (<350 eV, being transparent for ions with larger gyroradius. As a result, the penetration of plasma by finite gyroradius is considered as a possible source for the jet. The role of reconnection is briefly discussed. The electrodynamics of the TCS along with mass and momentum transfer across it are further discussed in the companion paper by Savin et al. (2006.

  12. A statistical study of the THEMIS satellite data for plasma sheet electrons carrying auroral upward field-aligned currents

    Science.gov (United States)

    Lee, S.; Shiokawa, K.; McFadden, J. P.

    2010-12-01

    The magnetospheric electron precipitation along the upward field-aligned currents without the potential difference causes diffuse aurora, and the magnetospheric electrons accelerated by a field-aligned potential difference cause the intense and bright type of aurora, namely discrete aurora. In this study, we are trying to find out when and where the aurora can be caused with or without electron acceleration. We statistically investigate electron density, temperature, thermal current, and conductivity in the plasma sheet using the data from the electrostatic analyzer (ESA) onboard the THEMIS-D satellite launched in 2007. According to Knight (Planet. Space Sci., 1973) and Lyons (JGR, 1980), the thermal current, jth(∝ nT^(1/2) where n is electron density and T is electron temperature in the plasma sheet), represents the upper limit to field aligned current that can be carried by magnetospheric electrons without field-aligned potential difference. The conductivity, K(∝ nT^(-1/2)), represents the efficiency of the upward field-aligned current (j) that the field-aligned potential difference (V) can produce (j=KV). Therefore, estimating jth and K in the plasma sheet is important in understanding the ability of plasma sheet electrons to carry the field-aligned current which is driven by various magnetospheric processes such as flow shear and azimuthal pressure gradient. Similar study was done by Shiokawa et al. (2000) based on the auroral electron data obtained by the DMSP satellites above the auroral oval and the AMPTE/IRM satellite in the near Earth plasma sheet at 10-18 Re on February-June 1985 and March-June 1986 during the solar minimum. The purpose of our study is to examine auroral electrons with pitch angle information inside 12 Re where Shiokawa et al. (2000) did not investigate well. For preliminary result, we found that in the dawn side inner magnetosphere (source of the region 2 current), electrons can make sufficient thermal current without field

  13. Energetic electron bursts in the plasma sheet and their relation with BBFs

    Science.gov (United States)

    Duan, A. Y.; Cao, J. B.; Dunlop, M.; Wang, Z. Q.

    2014-11-01

    We studied energetic electron bursts (EEBs) (40-250 keV) in the plasma sheet (PS) and their relation to bursty bulk flows (BBFs) using the data recorded by Cluster from 2001 to 2009. The EEBs in the PS can be classified into four types. Three types of EEBs are dispersionless, including EEBs accompanied with BBFs (V > 250 km/s) but without dipolarization front (DF); EEBs accompanied with both dipolarization front (DF) and BBF; and EEBs accompanied with DF and fast flow with V EEB, i.e., EEBs not accompanied with BBFs and DFs, is dispersed. The energetic electrons (40-130 keV) can be easily transported earthward by BBFs due to the strong dawn-dusk electric field embedded in BBFs. The DFs in BBFs can produce energetic electrons (40 to 250 keV). For the EEBs with DF and BBFs, the superposed epoch analyses show that the increase of energetic electron flux has two phases: gradual increase phase before DF and rapid increase phase concurrent with DF. In the PS around x = -18 RE, 60%-70% of EEBs are accompanied with BBFs, indicating that although hitherto there have been various acceleration mechanisms of energetic electrons, most of the energetic electrons in the PS are related with magnetic reconnection, and they are produced either directly by magnetic reconnection or indirectly by the DFs within BBFs. In the BBF's braking region of -12 RE EEBs are accompanied with BBFs. The corresponding ratio between EEBs and BBFs shows a dawn-dusk asymmetry.

  14. ISEE 3 observations during a plasma sheet encounter at 140 earth radii - Evidence for enhancement of reconnection at the distant neutral line

    Science.gov (United States)

    Scholer, M.; Terasawa, T.; Baker, D. N.; Zwickl, R. D.; Gloeckler, G.; Hovestadt, D.; Smith, E. J.; Tsurutani, B. T.

    1986-01-01

    A plasma sheet encounter of the ISEE-3 spacecraft in the distant tail at 140 earth radii on March 20, 1983 is studied using magnetic field, energetic particle, and plasma electron data sets. The H-component magnetograms from auroral magnetometer stations, intensity-time profiles, high resolution magnetic field measurements, and electron and proton angular distributions are analyzed. The dynamics of the plasma sheet displayed by the strong tailward and earthward directed ion beams, large northward and southward magnetic fields excursions, and short tailward and earthward plasma flows are described.

  15. Instabilities in a Plasma Coupled to a Neutral Population

    Science.gov (United States)

    Daughton, W.; Coppi, B.; Catto, P.; Krasheninnikov, S.

    1996-11-01

    Low temperature plasmas are often coupled to a neutral population through charge exchange or elastic collisions. The edge and divertor region of a tokamak and the ionosphere are a few well know examples. The linear stability of a coupled plasma - neutral system in plane geometry is examined and several relevant instabilities have been identified. One of these instabilities is an interchange type flute mode driven by the neutral pressure gradient. The second is a dissipative velocity shear instability^1 driven by the perpendicular gradient of a parallel velocity. Previously(B. Basu and B. Coppi, Journal of Geophysical Research), Vol. 94 No. A5 p. 5316 (1989) the neutral population had been treated as a uniform background insensitive to the perturbations in the plasma while in the present work the instability is allowed to perturb the neutrals as well as the plasma. The relevant dispersion relationships and instability conditions are presented. Supported in part by the U.S. Department of Energy

  16. Metro U.S.A. Data Sheet: Population Estimates and Selected Demographic Indicators for the Metropolitan Areas of the United States. Special edition of the United States Population Data Sheet.

    Science.gov (United States)

    Population Reference Bureau, Inc., Washington, DC.

    This poster-size data sheet presents population estimates and selected demographic indicators for the nation's 281 metropolitan areas. These areas are divided into 261 Metropolitan Statistical Areas (MSAs) and 20 Consolidated Metropolitan Statistical Areas (CMSAs), reporting units which replace the Standard Metropolitan Statistical Areas (SMSAs)…

  17. Role of magnetic field fluctuations in the Evolution of the kappa Distribution Functions in the Plasma Sheet

    Science.gov (United States)

    Espinoza, Cristobal; Antonova, Elizaveta; Stepanova, Marina; Valdivia, Juan Alejandro

    2016-07-01

    The evolution with the distance to Earth of ion and electron distribution functions in the plasma sheet, approximated by kappa distributions, was studied by Stepanova and Antonova (2015, JGRA 120). Using THEMIS data for 5 events of satellite alignments along the tail, covering between 5 and 30 Earth radii, they found that the kappa parameter increases tailwards, for both ions and electrons. In this work we analyse the magnetic fluctuations present in THEMIS data for the same 5 events. The aim is to explore the hypothesis proposed by Navarro et al. (2014, PRL 112), for solar wind plasmas, that the observed magnetic fluctuations could be closely related to spontaneous fluctuations in the plasma, if this can be described by stable distributions. Here we present our first results on the correlation between the spectral properties of the magnetic fluctuations and the observed parameters of the kappa distributions for different distances from Earth.

  18. Plasma Neutrophil Gelatinase-Associated Lipocalinin in the General Population

    DEFF Research Database (Denmark)

    Lindberg, Søren; Jensen, Jan S; Mogelvang, Rasmus;

    2014-01-01

    , when both markers were added to the Framingham risk score, NGAL conferred 3× to 4× the risk. CONCLUSIONS: Plasma NGAL is strongly associated with inflammation in the general population. NGAL independently associated with 10-year outcome, and when added to the Framingham risk score, NGAL both improves c...

  19. Low sheet resistance titanium nitride films by low-temperature plasma-enhanced atomic layer deposition using design of experiments methodology

    Energy Technology Data Exchange (ETDEWEB)

    Burke, Micheal, E-mail: micheal.burke@tyndall.ie; Blake, Alan; Povey, Ian M.; Schmidt, Michael; Petkov, Nikolay; Carolan, Patrick; Quinn, Aidan J., E-mail: aidan.quinn@tyndall.ie [Tyndall National Institute, University College Cork, Cork (Ireland)

    2014-05-15

    A design of experiments methodology was used to optimize the sheet resistance of titanium nitride (TiN) films produced by plasma-enhanced atomic layer deposition (PE-ALD) using a tetrakis(dimethylamino)titanium precursor in a N{sub 2}/H{sub 2} plasma at low temperature (250 °C). At fixed chamber pressure (300 mTorr) and plasma power (300 W), the plasma duration and N{sub 2} flow rate were the most significant factors. The lowest sheet resistance values (163 Ω/sq. for a 20 nm TiN film) were obtained using plasma durations ∼40 s, N{sub 2} flow rates >60 standard cubic centimeters per minute, and purge times ∼60 s. Time of flight secondary ion mass spectroscopy data revealed reduced levels of carbon contaminants in the TiN films with lowest sheet resistance (163 Ω/sq.), compared to films with higher sheet resistance (400–600 Ω/sq.) while transmission electron microscopy data showed a higher density of nanocrystallites in the low-resistance films. Further significant reductions in sheet resistance, from 163 Ω/sq. to 70 Ω/sq. for a 20 nm TiN film (corresponding resistivity ∼145 μΩ·cm), were achieved by addition of a postcycle Ar/N{sub 2} plasma step in the PE-ALD process.

  20. Multifluid MHD simulation of Saturn's magnetosphere: Dynamics of mass- and momentum-loading, and seasonal variation of the plasma sheet

    Science.gov (United States)

    Rajendar, A.; Paty, C. S.; Arridge, C. S.; Jackman, C. M.; Smith, H. T.

    2013-12-01

    Saturn's magnetosphere is driven externally, by the solar wind, and internally, by the planet's strong magnetic field, rapid rotation rate, and the addition of new plasma created from Saturn's neutral cloud. Externally, the alignment of the rotational and magnetic dipole axes, combined with Saturn's substantial inclination to its plane of orbit result in substantial curvature of the plasma sheet during solstice. Internally, new water group ions are produced in the inner regions of the magnetosphere from photoionization and electron-impact ionization of the water vapor and OH cloud sourced from Enceladus and other icy bodies in Saturn's planetary system. In addition to this, charge-exchange collisions between the relatively fast-moving water group ions and the slower neutrals results in a net loss of momentum from the plasma. In order to study these phenomena, we have made significant modifications to the Saturn multifluid model. This model has been previously used to investigate the external triggering of plasmoids and the interchange process using a fixed internal source rate. In order to improve the fidelity of the model, we have incorporated a physical source of mass- and momentum-loading by including an empirical representation of Saturn's neutral cloud and modifying the multifluid MHD equations to include mass- and momentum-loading terms. Collision cross-sections between ions, electrons, and neutrals are calculated as functions of closure velocity and energy at each grid point and time step, enabling us to simulate the spatially and temporally varying plasma-neutral interactions. In addition to this, by altering the angle of incidence of the solar wind relative to Saturn's rotational axis and applying a realistic latitudinally- and seasonally-varying ionospheric conductivity, we are also able to study seasonal effects on Saturn's magnetosphere. We use the updated multifluid simulation to investigate the dynamics of Saturn's magnetosphere, focusing specifically

  1. Evolution and structure of the plasma of current sheets forming in two-dimensional magnetic fields with a null line at low initial gas ionization and their interpretation

    Science.gov (United States)

    Ostrovskaya, G. V.; Frank, A. G.

    2012-04-01

    An analysis of the experimental data obtained by holographic interferometry in our work [1] makes it possible to explain most of the observed specific features of the structure and evolution of the plasma sheets developing in a two-dimensional magnetic field with a null line in a plasma with a low initial degree of ionization (≈10-4). The following two processes are shown to play a key role here: additional gas ionization in an electric field and the peculiarities of plasma dynamics in a current sheet expanding in time.

  2. Latitude-energy structure of multiple ion beamlets in Polar/TIMAS data in plasma sheet boundary layer and boundary plasma sheet below 6 RE radial distance: basic properties and statistical analysis

    Directory of Open Access Journals (Sweden)

    W. K. Peterson

    2005-03-01

    Full Text Available Velocity dispersed ion signatures (VDIS occurring at the plasma sheet boundary layer (PSBL are a well reported feature. Theory has, however, predicted the existence of multiple ion beamlets, similar to VDIS, in the boundary plasma sheet (BPS, i.e. at latitudes below the PSBL. In this study we show evidence for the multiple ion beamlets in Polar/TIMAS ion data and basic properties of the ion beamlets will be presented. Statistics of the occurrence frequency of ion multiple beamlets show that they are most common in the midnight MLT sector and for altitudes above 4 RE, while at low altitude (≤3 RE, single beamlets at PSBL (VDIS are more common. Distribution functions of ion beamlets in velocity space have recently been shown to correspond to 3-dimensional hollow spheres, containing a large amount of free energy. We also study correlation with ~100 Hz waves and electron anisotropies and consider the possibility that ion beamlets correspond to stable auroral arcs.

  3. ISEE-3 observations of a viscously-driven plasma sheet: magnetosheath mass and/or momentum transfer?

    Science.gov (United States)

    Mist, R. T.; Owen, C. J.

    2002-05-01

    A statistical analysis of data from the ISEE-3 distant tail campaign is presented. We investigate the mechanism driving slow, tailward flows observed in the plasma sheet. The possibility that these slow flows are driven by mass and/or momentum transfer across the distant tail magnetopause is explored. We establish that 40% of these flows could be driven by the transfer of approximately 4% of the magnetosheath momentum flux into the magnetotail. Current understanding of the Kelvin-Helmholtz instability suggests that this figure is consistent with the amount of momentum flux transfer produced by this mechanism. We also consider the possibility that these flows are solely driven by transferring magnetosheath plasma across the magnetopause. We find that there is sufficient mass observed on these field lines for this to be the sole driving mechanism for only 27% of the observed slow flows.

  4. Resonant scattering of central plasma sheet protons by multiband EMIC waves and resultant proton loss timescales

    Science.gov (United States)

    Cao, Xing; Ni, Binbin; Liang, Jun; Xiang, Zheng; Wang, Qi; Shi, Run; Gu, Xudong; Zhou, Chen; Zhao, Zhengyu; Fu, Song; Liu, Jiang

    2016-02-01

    This is a companion study to Liang et al. (2014) which reported a "reversed" energy-latitude dispersion pattern of ion precipitation in that the lower energy ion precipitation extends to lower latitudes than the higher-energy ion precipitation. Electromagnetic ion cyclotron (EMIC) waves in the central plasma sheet (CPS) have been suggested to account for this reversed-type ion precipitation. To further investigate the association, we perform a comprehensive study of pitch angle diffusion rates induced by EMIC wave and the resultant proton loss timescales at L = 8-12 around the midnight. Comparing the proton scattering rates in the Earth's dipole field and a more realistic quiet time geomagnetic field constructed from the Tsyganenko 2001 (T01) model, we find that use of a realistic, nondipolar magnetic field model not only decreases the minimum resonant energies of CPS protons but also considerably decreases the limit of strong diffusion and changes the proton pitch angle diffusion rates. Adoption of the T01 model increases EMIC wave diffusion rates at > ~ 60° equatorial pitch angles but decreases them at small equatorial pitch angles. Pitch angle scattering coefficients of 1-10 keV protons due to H+ band EMIC waves can exceed the strong diffusion rate for both geomagnetic field models. While He+ and O+ band EMIC waves can only scatter tens of keV protons efficiently to cause a fully filled loss cone at L > 10, in the T01 magnetic field they can also cause efficient scattering of ~ keV protons in the strong diffusion limit at L > 10. The resultant proton loss timescales by EMIC waves with a nominal amplitude of 0.2 nT vary from a few hours to several days, depending on the wave band and L shell. Overall, the results demonstrate that H+ band EMIC waves, once present, can act as a major contributor to the scattering loss of a few keV protons at lower L shells in the CPS, accounting for the reversed energy-latitude dispersion pattern of proton precipitation at low

  5. Effects of solar wind ultralow-frequency fluctuations on plasma sheet electron temperature: Regression analysis with support vector machine

    Science.gov (United States)

    Wang, Chih-Ping; Kim, Hee-Jeong; Yue, Chao; Weygand, James M.; Hsu, Tung-Shin; Chu, Xiangning

    2017-04-01

    To investigate whether ultralow-frequency (ULF) fluctuations from 0.5 to 8.3 mHz in the solar wind and interplanetary magnetic field (IMF) can affect the plasma sheet electron temperature (Te) near geosynchronous distances, we use a support vector regression machine technique to decouple the effects from different solar wind parameters and their ULF fluctuation power. Te in this region varies from 0.1 to 10 keV with a median of 1.3 keV. We find that when the solar wind ULF power is weak, Te increases with increasing southward IMF Bz and solar wind speed, while it varies weakly with solar wind density. As the ULF power becomes stronger during weak IMF Bz ( 0) or northward IMF, Te becomes significantly enhanced, by a factor of up to 10. We also find that mesoscale disturbances in a time scale of a few to tens of minutes as indicated by AE during substorm expansion and recovery phases are more enhanced when the ULF power is stronger. The effect of ULF powers may be explained by stronger inward radial diffusion resulting from stronger mesoscale disturbances under higher ULF powers, which can bring high-energy plasma sheet electrons further toward geosynchronous distance. This effect of ULF powers is particularly important during weak southward IMF or northward IMF when convection electric drift is weak.

  6. Multi-instrument observations of the ionospheric counterpart of a bursty bulk flow in the near-Earth plasma sheet

    Directory of Open Access Journals (Sweden)

    A. Grocott

    2004-04-01

    Full Text Available On 07 September 2001 the Cluster spacecraft observed a "bursty bulk flow" event in the near-Earth central plasma sheet. This paper presents a detailed study of the coincident ground-based observations and attempts to place them within a simple physical framework. The event in question occurs at ~22:30 UT, some 10min after a southward turning of the IMF. IMAGE and SAMNET magnetometer measurements of the ground magnetic field reveal perturbations of a few tens of nT and small amplitude Pi2 pulsations. CUTLASS radar observations of ionospheric plasma convection show enhanced flows out of the polar cap near midnight, accompanied by an elevated transpolar voltage. Optical data from the IMAGE satellite also show that there is a transient, localised ~1 kR brightening in the UV aurora. These observations are consistent with the earthward transport of plasma in the tail, but also indicate the absence of a typical "large-scale" substorm current wedge. An analysis of the field-aligned current system implied by the radar measurements does suggest the existence of a small-scale current "wedgelet", but one which lacks the global scale and high conductivities observed during substorm expansions.

    Key words. Ionosphere (auroral ionosphere; ionospheremagnetosphere interactions; plasma convection

  7. Observation of a planetward ion beam in the plasma sheet boundary layer at Saturn following tail reconnection

    Science.gov (United States)

    Jackman, C. M.

    2014-04-01

    We present an interval of data from 2006 when the Cassini spacecraft was located 32 RS (1 RS = 60268km) downtail, at a local time of 22:00 hrs and a latitude of 13.8°. The interval in question displayed a range of dynamic behaviour, including a southward turning of the tail magnetic field, indicative of a dipolarization, and an energetic, fast, planetward beam of ions. Preliminary interpretation of this event suggests that it represents a reconnection-driven ion beam in Saturn's magnetotail plasma sheet boundary layer. This event is explored using several of the Cassini instruments to build up a picture of the reconfiguration of the tail in terms of local and global effects.

  8. Relationship between FAC at plasma sheet boundary layers and AE index during storms from August to October,2001

    Institute of Scientific and Technical Information of China (English)

    DUNLOP; M

    2008-01-01

    Unlike the previous single (dual) satellite observation, the four ClusterII satellites make it possible to directly compute the continuous field-aligned current (FAC) density according to the magnetic data from them and to enable the investigation of the relationship between the FAC and geomagnetic activity. This paper analyzes the observation data when the Cluster satellites crossed the plasma sheet bound- ary layer (PSBL) in the magnetotail during the two magnetic storms in August to October 2001. According to the data, during the magnetic storms the relationship between the variations of FAC and AE index turned out to be: 1) FAC was obviously increasing during the storms; 2) FAC density was approximately negatively corre- lated with AE index from the sudden commencement to the early main phase of the storm; 3) they were approximately positively correlated during the late main phase and early recovery phase; 4) they were no apparent correlation during the late re- covery phase.

  9. Nanoshaping field emitters from glassy carbon sheets: a new functionality induced by H-plasma etching.

    Science.gov (United States)

    Gay, S; Orlanducci, S; Passeri, D; Rossi, M; Terranova, M L

    2016-09-14

    This paper reports on the morphological and electrical characterization at the nanometer scale and the investigation of the field emission characteristics of glassy carbon (GC) plates which underwent H-induced physical/chemical processes occurring in a dual-mode MW-RF plasma reactor. Plasma treatment produced on the GC surface arrays of vertically aligned conically shaped nanostructures, with density and height depending on the plasma characteristics. Two kinds of samples obtained under two different bias regimes have been deeply analyzed using an AFM apparatus equipped with tools for electric forces and surface potential measurements. The features of electron emission via the Field Emission (FE) mechanism have been correlated with the morphology and the structure at the nanoscale of the treated glassy carbon samples. The measured current density and the characteristics of the emission, which follow the Fowler-Nordheim law, indicate that the plasma-based methodology utilized for the engineering of the GC surfaces is able to turn conventional GC plates into efficient emission devices. The outstanding properties of GC suggest the use of such nanostructured materials for the assembling of cold cathodes to be used in a harsh environment and under extreme P/T conditions.

  10. Observations of energetic electrons /E no less than about 200 keV/ in the earth's magnetotail - Plasma sheet and fireball observations

    Science.gov (United States)

    Baker, D. N.; Stone, E. C.

    1977-01-01

    An earlier paper by the authors (1976) has reported on energetic electron anisotropies observed in conjunction with the acceleration regions identified by Frank et al., (1976). The present paper gives more detailed analyses of observations in the distant plasma sheet, including specific features of intensities, energy spectra, and pitch angle distributions of the very energetic electrons associated with intense plasma particle events, with energies ranging between 50 eV and 45 keV, detected with an electron/isotope spectrometer aboard the earth-orbiting spacecraft Imp 8. Two domains are considered: the plasma sheet and the regions near and within the localized magnetotail acceleration regions known as the fireball regions. The instrumentation used offered a number of observational advantages over many previous studies, including inherently low background, large geometric factors, excellent species identification, good angular distribution measurement capability, and availability of high resolution of differential intensities.

  11. Plasma YKL-40 and total and disease-specific mortality in the general population

    DEFF Research Database (Denmark)

    Johansen, Julia S; Bojesen, Stig E; Tybjaerg-Hansen, Anne

    2010-01-01

    Increased plasma YKL-40 is associated with short-term survival in patients with cardiovascular disease and cancer. We tested the hypothesis that increased plasma YKL-40 is associated with total and disease-specific mortality in the general population....

  12. Tail reconnection region versus auroral activity inferred from conjugate ARTEMIS plasma sheet flow and auroral observations

    Science.gov (United States)

    Nishimura, Y.; Lyons, L. R.; Xing, X.; Angelopoulos, V.; Donovan, E. F.; Mende, S. B.; Bonnell, J. W.; Auster, U.

    2013-09-01

    sheet flow bursts have been suggested to correspond to different types of auroral activity, such as poleward boundary intensifications (PBIs), ensuing auroral streamers, and substorms. The flow-aurora association leads to the important question of identifying the magnetotail source region for the flow bursts and how this region depends on magnetic activity. The present study uses the ARTEMIS spacecraft coordinated with conjugate ground-based auroral imager observations to identify flow bursts beyond 45 RE downtail and corresponding auroral forms. We find that quiet-time flows are directed dominantly earthward with a one-to-one correspondence with PBIs. Flow bursts during the substorm recovery phase and during steady magnetospheric convection (SMC) periods are also directed earthward, and these flows are associated with a series of PBIs/streamers lasting for tens of minutes with similar durations to that of the series of earthward flows. Presubstorm onset flows are also earthward and associated with PBIs/streamers. The earthward flows during those magnetic conditions suggest that the flow bursts, which lead to PBIs and streamers, originate from further downtail of ARTEMIS, possibly from the distant-tail neutral line (DNL) or tailward-retreated near-Earth neutral line (NENL) rather than from the nominal NENL location in the midtail. We find that tailward flows are limited primarily to the substorm expansion phase. They continue throughout the period of auroral poleward expansion, indicating that the expansion-phase flows originate from the NENL and that NENL activity is closely related to the auroral expansion of the substorm expansion phase.

  13. Observation of an Extremely Large-Density Heliospheric Plasma Sheet Compressed by an Interplanetary Shock at 1 AU

    Science.gov (United States)

    Wu, Chin-Chun; Liou, Kan; Lepping, R. P.; Vourlidas, Angelos; Plunkett, Simon; Socker, Dennis; Wu, S. T.

    2017-08-01

    At 11:46 UT on 9 September 2011, the Wind spacecraft encountered an interplanetary (IP) fast-forward shock. The shock was followed almost immediately by a short-duration (˜ 35 minutes) extremely dense pulse (with a peak ˜ 94 cm-3). The pulse induced an extremely large positive impulse (SYM-H = 74 nT and Dst = 48 nT) on the ground. A close examination of other in situ parameters from Wind shows that the density pulse was associated with i) a spike in the plasma β (ratio of thermal to magnetic pressure), ii) multiple sign changes in the azimuthal component of the magnetic field (B_{φ}), iii) a depressed magnetic field magnitude, iv) a small radial component of the magnetic field, and v) a large (> 90°) change in the suprathermal (˜ 255 eV) electron pitch angle across the density pulse. We conclude that the density pulse is associated with the heliospheric plasma sheet (HPS). The thickness of the HPS is estimated to be {˜} 8.2×105 km. The HPS density peak is about five times the value of a medium-sized density peak inside the HPS (˜ 18 cm-3) at 1 AU. Our global three-dimensional magnetohydrodynamic simulation results (Wu et al. in J. Geophys. Res. 212, 1839, 2016) suggest that the extremely large density pulse may be the result of the compression of the HPS by an IP shock crossing or an interaction between an interplanetary shock and a corotating interaction region.

  14. Recombination and population inversion in plasmas generated by tunneling ionization.

    Science.gov (United States)

    Pert, G J

    2006-06-01

    Above-threshold ionization (ATI) ionization by linearly polarized light has been proposed by several authors as a means of driving recombination lasers in the soft x-ray spectral region. The pump radiation generates a cold electron plasma with ions in a single ionization stage, which is an ideal starting condition for strong recombination. Population inversions form during the recombination cascade to the ground state of the next ionization stage. In the absence of any relaxation the electron distribution is strongly peaked near zero energy. However, a number of different processes all heat the cold electrons towards Maxwellian, and may thereby reduce the recombination rate in the higher levels. Using numerical models we investigate these relaxation processes and their effect on recombination. We show that the recombination can be well described by the standard cascade model, provided an appropriate temperature is used. We examine two cases in detail, hydrogen-like lithium where the inversion is with respect to the ground state, and lithium-like nitrogen where it is with the first excited state. The two cases differ markedly in the degree of relaxation achieved, and in the duration of the population inversion.

  15. Comparative analysis of the processing accuracy of high strength metal sheets by AWJ, laser and plasma

    Science.gov (United States)

    Radu, M. C.; Schnakovszky, C.; Herghelegiu, E.; Tampu, N. C.; Zichil, V.

    2016-08-01

    Experimental tests were carried out on two high-strength steel materials (Ramor 400 and Ramor 550). Quantification of the dimensional accuracy was achieved by measuring the deviations from some geometric parameters of part (two lengths and two radii). It was found that in case of Ramor 400 steel, at the jet inlet, the deviations from the part radii are quite small for all the three analysed processes. Instead for the linear dimensions, the deviations are small only in case of laser cutting. At the jet outlet, the deviations raised in small amount compared to those obtained at the jet inlet for both materials as well as for all the three processes. Related to Ramor 550 steel, at the jet inlet the deviations from the part radii are very small in case of AWJ and laser cutting but larger in case of plasma cutting. At the jet outlet, the deviations from the part radii are very small for all processes; in case of linear dimensions, there was obtained very small deviations only in the case of laser processing, the other two processes leading to very large deviations.

  16. pTC-1 observation of ion high-speed flow reversal in the near-Earth plasma sheet during substorm

    Institute of Scientific and Technical Information of China (English)

    H.; RME; I.; DANDOURAS; C.; M.; CARR

    2008-01-01

    Based on measurements of FGM and HIA on board TC-1 at its apogee on Septem-ber 14, 2004, we analyzed the ion high-speed flows in the near-Earth plasma sheet observed during the substorm expansion phase. Strong tailward high-speed flows (Vx ~ -350 km/s) were first seen at about X ~ -13.2 RE in near-Earth magnetotail, one minute later the flows reversed from tailward to earthward. The reversal process occurred quickly after the substorm expansion onset. The near-Earth magnetotail plasma sheet was one of key regions for substorm onset. Our analysis showed that the ion flow reversal from tailward to earthward was likely to be in close relation with the substorm expansion initiation and might play an important role in trigger-ing the substorm expansion onset.

  17. Using PEACE Data from the four CLUSTER Spacecraft to Measure Compressibility, Vorticity, and the Taylor Microscale in the Magnetosheath and Plasma Sheet

    Science.gov (United States)

    Goldstein, Melvyn L.; Parks, George; Gurgiolo, C.; Fazakerley, Andrew N.

    2008-01-01

    We present determinations of compressibility and vorticity in the magnetosheath and plasma sheet using moments from the four PEACE thermal electron instruments on CLUSTER. The methodology used assumes a linear variation of the moments throughout the volume defined by the four satellites, which allows spatially independent estimates of the divergence, curl, and gradient. Once the vorticity has been computed, it is possible to estimate directly the Taylor microscale. We have shown previously that the technique works well in the solar wind. Because the background flow speed in the magnetosheath and plasma sheet is usually less than the Alfven speed, the Taylor frozen-in-flow approximation cannot be used. Consequently, this four spacecraft approach is the only viable method for obtaining the wave number properties of the ambient fluctuations. Our results using electron velocity moments will be compared with previous work using magnetometer data from the FGM experiment on Cluster.

  18. Experimental study of nonlinear interaction of plasma flow with charged thin current sheets: 2. Hall dynamics, mass and momentum transfer

    Directory of Open Access Journals (Sweden)

    S. Savin

    2006-01-01

    Full Text Available Proceeding with the analysis of Amata et al. (2005, we suggest that the general feature for the local transport at a thin magnetopause (MP consists of the penetration of ions from the magnetosheath with gyroradius larger than the MP width, and that, in crossing it, the transverse potential difference at the thin current sheet (TCS is acquired by these ions, providing a field-particle energy exchange without parallel electric fields. It is suggested that a part of the surface charge is self-consistently produced by deflection of ions in the course of inertial drift in the non-uniform electric field at MP. Consideration of the partial moments of ions with different energies demonstrates that the protons having gyroradii of roughly the same size or larger than the MP width carry fluxes normal to MP that are about 20% of the total flow in the plasma jet under MP. This is close to the excess of the ion transverse velocity over the cross-field drift speed in the plasma flow just inside MP (Amata et al., 2005, which conforms to the contribution of the finite-gyroradius inflow across MP. A linkage through the TCS between different plasmas results from the momentum conservation of the higher-energy ions. If the finite-gyroradius penetration occurs along the MP over ~1.5 RE from the observation site, then it can completely account for the formation of the jet under the MP. To provide the downstream acceleration of the flow near the MP via the cross-field drift, the weak magnetic field is suggested to rotate from its nearly parallel direction to the unperturbed flow toward being almost perpendicular to the accelerated flow near the MP. We discuss a deceleration of the higher-energy ions in the MP normal direction due to the interaction with finite-scale electric field bursts in the magnetosheath flow frame, equivalent to collisions, providing a charge separation. These effective collisions, with a nonlinear frequency proxy of the order of the proton

  19. Optimization Of Pulsed Current Parameters To Minimize Pitting Corrosion İn Pulsed Current Micro Plasma Arc Welded Aısı 304l Sheets Using Genetic Algorithm

    Directory of Open Access Journals (Sweden)

    Kondapalli Siva Prasad

    2013-06-01

    Full Text Available Austenitic stainless steel sheets have gathered wide acceptance in the fabrication of components, which require high temperature resistance and corrosion resistance, such as metal bellows used in expansion joints in aircraft, aerospace and petroleum industry. In case of single pass welding of thinner sections of this alloy, Pulsed Current Micro Plasma Arc Welding (PCMPAW was found beneficial due to its advantages over the conventional continuous current process. This paper highlights the development of empirical mathematical equations using multiple regression analysis, correlating various process parameters to pitting corrosion rates in PCMPAW of AISI 304L sheets in 1 Normal HCl. The experiments were conducted based on a five factor, five level central composite rotatable design matrix. A Genetic Algorithm (GA was developed to optimize the process parameters for minimizing the pitting corrosion rates.

  20. Elevated plasma vitamin B12 levels and cancer prognosis: A population-based cohort study

    DEFF Research Database (Denmark)

    Arendt, Johan Frederik Håkonsen; Farkas, Dora Kormendine; Pedersen, Lars;

    2015-01-01

    BACKGROUND: Elevated plasma vitamin B12 levels (cobalamin, Cbl) are associated with increased short-term cancer risk among patients referred for this laboratory measurement. We aimed to assess prognosis in cancer patients with elevated plasma Cbl. METHODS: We conducted a population-based cohort...

  1. Elemental Quantitative Distribution and Statistical Analysis on Cross Section of Stainless Steel Sheet by Laser Ablation Inductively Coupled Plasma Mass Spectrometry

    Institute of Scientific and Technical Information of China (English)

    Qian-hua LUO; Hai-zhou WANG

    2015-01-01

    An innovative application of laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) technique in illustrating elemental distributions on stainless steel sheets was presented. The technique proved to be a systematic and accurate ap-proach in producing visual images or maps of elemental distributions at cross-sectional surface of a stainless steel sheet. Two stain-less steel sheets served as research objects: 3 mm×1 300 mm hot-rolled stainless steel plate and 1 mm×1 260 mm cold-rolled plate. The cross-sectional surfaces of the two samples at 1/4 position along the width direction were scanned (raster area-44 mm2 and 11 mm2) with a focused laser beam (wavelength 213 nm, diameter of laser crater 100 μm, and laser power 1.6 mJ) in a laser abla-tion chamber. The laser ablation system was coupled to a quadrupole ICP-MS, which made the detection of ion intensities of27Al+, 44Ca+,47Ti+,55Mn+ and56Fe+ within an area of interest possible. One-dimensional (1D) content line distribution maps and two-dimensional (2D) contour maps for speciifc positions or areas were plotted to indicate the element distribution of a target area with high accuracy. Statistic method was used to analyze the acquired data by calculating median contents, maximum segregation, sta-tistic segregation and content-frequency distribution.

  2. The Origin of the Near-Earth Plasma Population During a Substorm on November 24, 1996

    Science.gov (United States)

    Ashour-Abdalla, M.; El-Alaoui, M.; Peroomian, V.; Walker, R. J.; Raeder, J.; Frank, L. A.; Paterson, W. R.

    1999-01-01

    We investigate the origins and the transport of ions observed in the near-Earth plasma sheet during the growth and expansion phases of a magnetospheric substorm that occurred on November 24, 1996. Ions observed at Geotail were traced backward in time in time-dependent magnetic and electric fields to determine their origins and the acceleration mechanisms responsible for their energization. Results from this investigation indicate that, during the growth phase of the substorm, most of the ions reaching Geotail had origins in the low latitude boundary layer (LLBL) and had already entered the magnetosphere when the growth phase began. Late in the growth phase and in the expansion phase a higher proportion of the ions reaching Geotail had their origin in the plasma mantle. Indeed, during the expansion phase more than 90% of the ions seen by Geotail were from the mantle. The ions were accelerated enroute to the spacecraft; however, most of the ions' energy gain was achieved by non-adiabatic acceleration while crossing the equatorial current sheet just prior to their detection by Geotail. In general, the plasma mantle from both southern and northern hemispheres supplied non-adiabatic ions to Geotail, whereas the LLBL supplied mostly adiabatic ions to the distributions measured by the spacecraft. Distribution functions computed at the ion sources indicate that ionospheric ions reaching Geotail during the expansion phase were significantly heated. Plasma mantle source distributions indicated the presence of a high-latitude reconnection region that allowed ion entry into the magnetosphere when the IMF was northward. These ions reached Geotail during the expansion phase. Ions from the traditional plasma mantle had access to the spacecraft throughout the substorm.

  3. Population inversion in plasmas generated during recombination cascades.

    Science.gov (United States)

    Pert, G J

    2007-11-01

    The collisional-radiative model for hydrogenlike ions is used to investigate the scaling of recombination at low temperatures in order to identify the necessary conditions of electron density and temperature, which will allow population inversion between the first excited state and the ground state to be developed. Numerical calculations show that at low temperatures the population growth in the hydrogenic states can be represented by similarity relations. The physical origin of these forms is presented. A table of minimum densities at which inversion will occur is given as a function of temperature for ions of arbitrary atomic number.

  4. Propagation and oblique collision of electron-acoustic solitons in two-electron-populated quantum plasmas

    Indian Academy of Sciences (India)

    M Akbari-Moghanjoughi; N Ahmadzadeh-Khosroshahi

    2011-08-01

    Oblique interaction of small- but finite-amplitude KdV-type electron-acoustic solitary excitations is examined in an unmagnetized two-electron-populated degenerate quantum electron–ion plasma in the framework of quantum hydrodynamics model using the extended Poincaré–Lighthill–Kuo (PLK) perturbation method. Critical plasma parameter is found to distinguish the types of solitons and their interaction phase-shifts. It is shown that, depending on the critical quantum diffraction parameter cr, both compressive and rarefactive solitary excitations may exist in this plasma and their collision phase-shifts can be either positive or negative for the whole range of collision angles 0 < θ < .

  5. Overestimation of vitamin a supplementation coverage from district tally sheets demonstrates importance of population-based surveys for program improvement: lessons from Tanzania.

    Directory of Open Access Journals (Sweden)

    Christina Nyhus Dhillon

    Full Text Available BACKGROUND: Tanzania has conducted a national twice-yearly Vitamin A supplementation (VAS campaign since 2001. Administrative coverage rates based on tally sheets consistently report >90% coverage; however the accuracy of these rates are uncertain due to potential errors in tally sheets and their aggregation, incomplete or inaccurate reporting from distribution sites, and underestimating the target population. OBJECTIVES: The post event coverage survey in Mainland Tanzania sought to validate tally-sheet based national coverage estimates of VAS and deworming for the June 2010 mass distribution round, and to characterize children missed by the national campaign. METHODS: WHO/EPI randomized cross-sectional cluster sampling methodology was adapted for this study, using 30 clusters by 40 individuals (n = 1200, in addition to key informant interviews. Households with children 6-59 months of age were included in the study (12-59 months for deworming analysis. Chi-squared tests and logistic regression analysis were used to test differences between children reached and not reached by VAS. Data was collected within six weeks of the June 2010 round. RESULTS: A total of 1203 children, 58 health workers, 30 village leaders and 45 community health workers were sampled. Preschool VAS coverage was 65% (95% CI: 62.7-68.1, approximately 30% lower than tally-sheet coverage estimates. Factors associated with not receiving VAS were urban residence [OR = 3.31; p = 0.01], caretakers who did not hear about the campaign [OR = 48.7; p<0.001], and Muslim households [OR<3.25; p<0.01]. There were no significant differences in VAS coverage by child sex or age, or maternal age or education. CONCLUSION: Coverage estimation for vitamin A supplementation programs is one of most powerful indicators of program success. National VAS coverage based on a tally-sheet system overestimated VAS coverage by ∼30%. There is a need for representative population

  6. Nonlinear kinetic Alfvén waves with non-Maxwellian electron population in space plasmas

    Science.gov (United States)

    Masood, W.; Qureshi, M. N. S.; Yoon, P. H.; Shah, H. A.

    2015-01-01

    The present work discusses the effects of non-Maxwellian electron distributions on kinetic Alfvén waves in low-beta plasmas. Making use of the two-potential theory and employing the Sagdeev potential approach, the existence of solitary kinetic Alfvén waves having arbitrary amplitude is investigated. It is found that the use of non-Maxwellian population of electrons in the study of kinetic Alfvén waves leads to solutions corresponding to solitary structures that do not exist for Maxwellian electrons. The present investigation solves the riddle of plasma density fluctuations associated with strong electromagnetic perturbations observed by the Freja satellite. The present findings can also be applied to regions of space where various satellite missions have observed the presence of suprathermal populations of plasma species and where the low β assumption is valid.

  7. Plasma heating in a post eruption Current Sheet: a case study based on ultraviolet, soft, and hard X-ray data

    CERN Document Server

    Susino, Roberto; Krucker, Säm

    2013-01-01

    Off-limb observations of the solar corona after Coronal Mass Ejections (CMEs) often show strong, compact, and persistent UV sources behind the eruption. They are primarily observed by the SOHO/UVCS instrument in the "hot" Fe XVIII {\\lambda}974 {\\AA} line and are usually interpreted as a signature of plasma heating due to magnetic reconnection in the post-CME Current Sheet (CS). Nevertheless, the physical process itself and the altitude of the main energy release are currently not fully understood. In this work, we studied the evolution of plasma heating after the CME of 2004 July 28 by comparing UV spectra acquired by UVCS with soft X-ray (SXR) and hard X-ray (HXR)images of the post-flare loops taken by GOES/SXI and RHESSI. The X-ray data show a long-lasting extended source that is rising upwards, toward the high-temperature source detected by UVCS. UVCS data show the presence of significant non-thermal broadening in the CS (signature of turbulent motions) and a strong density gradient across the CS region. T...

  8. Elevated Plasma YKL-40 Levels and Ischemic Stroke in the General Population

    DEFF Research Database (Denmark)

    Kjaergaard, A.D.; Bojesen, S.E.; Johansen, J.S.

    2010-01-01

    Objective: We hypothesized that elevated plasma YKL-40 levels are associated with increased risk of ischemic cardiovascular disease in the general population. In contrast to C-reactive protein (CRP) produced in the liver in response to inflammation, YKL-40 is produced by lipid-laden macrophages...... inside the vessel wall. Methods: We measured plasma YKL-40 in 8,899 21- to 93-year-old participants of the Copenhagen City Heart Study 1991-1994 examination, and followed them for up to 18 years. Endpoints were ischemic stroke, ischemic cerebrovascular disease, myocardial infarction, and ischemic heart...

  9. Drift wave stabilized by an additional streaming ion or plasma population.

    Science.gov (United States)

    Bashir, M F; Vranjes, J

    2015-03-01

    It is shown that the universally unstable kinetic drift wave in an electron-ion plasma can very effectively be suppressed by adding an extra flowing ion (or plasma) population. The effect of the flow of the added ions is essential, their response is of the type (vph-vf0)exp[-(vph-vf0)2], where vf0 is the flow speed and vph is the phase speed parallel to the magnetic field vector. The damping is strong and it is mainly due to this ion exponential term, and this remains so for vf0vph.

  10. Drift wave stabilized by an additional streaming ion or plasma population

    CERN Document Server

    Bashir, M F

    2015-01-01

    It is shown that the universally unstable kinetic drift wave in an electron-ion plasma can very effectively be suppressed by adding an extra flowing ion (or plasma) population. The effect of the flow of the added ions is essential, their response is of the type (vph-vf0) exp[-(vph-vf0)^2], where vf0 is the flow speed and vph phase speed parallel to the magnetic field vector. The damping is strong and it is mainly due to this ion exponential term, and this remains so for vf0 < vph.

  11. Plasma testosterone in the general population, cancer prognosis and cancer risk

    DEFF Research Database (Denmark)

    Orsted, D D; Nordestgaard, B G; Bojesen, S E

    2014-01-01

    BACKGROUND: Testosterone is an important anabolic hormone in humans and in vitro testosterone stimulates growth of lung and colon cancer cells. We tested the hypothesis that plasma testosterone associate with increased risk of cancer and with increased risk of early death after cancer. MATERIALS...... AND METHODS: Plasma testosterone was measured in 8771 20- to 94-year-old men and women who participated in a prospective study of the general population. Participants were included in 1981-1983 and followed for a median of 22 years (range: 0-30 years). RESULTS: During follow-up, 1140 men and 809 women...

  12. STUDIES ON SURFACE CHARACTERIZATION AND ECOMATERIAL SHEET DEGRADATION OF BASALT FIBERS BY PLASMA TREATMENTS AND WOOD FIBERS

    Institute of Scientific and Technical Information of China (English)

    Guangjian Wang; Yajie Guo; Deku Shang; linna Hu; Zhenhua Guo; Kailiang Zhang

    2004-01-01

    Plasma surface modification (Argon: Hydrogen =0.6:0.4) of basalt fibers was investigated and the element contents of basalt and wood fibers were determined by X-ray energy dispersion spectroscope (EDS).Configuration of basalt fibers was described by means of confocal Laser Raman microRaman spectrometer and Fourier transform infrared spectroscopy. And the morphology of fiber surface was studied with scanning electron microscope(SEM). The modified samples were characterized by X-ray photoelectron spectra (XPS). The results showed that the roughness of basalt fibers was increased with the increase of exposure time of plasma. At the same time the wettability and surface characteristics such as active groups of NH2, OH were improved as well. Basaltfibers were of good chemical stability, better mechanism intension and thermo-stability etc. They mainly consist of [SiO4]4-,[Si2O6]4-, [Si2O5]2-. Further experiments demostrated that they were degraded into edaphic matrix after use.Therefore, they were environmentally friendly.

  13. STUDIES ON SURFACE CHARACTERIZATION AND ECOMATERIAL SHEET DEGRADATION OF BASALT FIBERS BY PLASMA TREATMENTS AND WOOD FIBERS

    Institute of Scientific and Technical Information of China (English)

    GuangjianWang; YajieGuo; DekuShang; linnaHu; ZhenhuaGuo; KailiangZhang

    2004-01-01

    plasma surtace modification (Argon: Hydrogen=0.6:0.4) of basalt fibers was mvestigated and the element contents of basalt and wood fibers were determined by X-ray energy dispersion spectroscope (EDS). configuration of basalt fibers was described by means of confocal Laser Raman microRaman spectrometer and Fourier transform infrared spectroscopy. And the morphology of fiber surface was studied with scanning electron microscope (SEM). The modified samples were characterized by X-ray photoelectron spectra (XPS). The results showed that the roughness of basalt fibers was increased with the increase of exposure time of plasma. At the same time the wettability and surface characteristics such as active groups of NH2, OH were improved as well. Basalt fibers were of good chemical stability, better mechanism intension and thermo-stability etc. They mainly consist of [SiO4]4-, [Si2O6]4-,[Si2O5]2-. Further experiments demostrated that they were degraded into edaphic matrix after use. Therefore, they were environmentally friendly.

  14. Pooled population pharmacokinetic model of imipenem in plasma and the lung epithelial lining fluid

    Science.gov (United States)

    Rizk, Matthew L.; Lala, Mallika; Chavez‐Eng, Cynthia; Visser, Sandra A. G.; Kerbusch, Thomas; Danhof, Meindert; Rao, Gauri; van der Graaf, Piet H.

    2016-01-01

    Aims Several clinical trials have confirmed the therapeutic benefit of imipenem for treatment of lung infections. There is however no knowledge of the penetration of imipenem into the lung epithelial lining fluid (ELF), the site of action relevant for lung infections. Furthermore, although the plasma pharmacokinetics (PK) of imipenem has been widely studied, most studies have been based on selected patient groups. The aim of this analysis was to characterize imipenem plasma PK across populations and to quantify imipenem ELF penetration. Methods A population model for imipenem plasma PK was developed using data obtained from healthy volunteers, elderly subjects and subjects with renal impairment, in order to identify predictors for inter‐individual variability (IIV) of imipenem PK. Subsequently, a clinical study which measured plasma and ELF concentrations of imipenem was included in order to quantify lung penetration. Results A two compartmental model best described the plasma PK of imipenem. Creatinine clearance and body weight were included as subject characteristics predictive for IIV on clearance. Typical estimates for clearance, central and peripheral volume, and inter‐compartmental clearance were 11.5 l h–1, 9.37 l, 6.41 l, 13.7 l h–1, respectively (relative standard error (RSE) <8%). The distribution of imipenem into ELF was described using a time‐independent penetration coefficient of 0.44 (RSE 14%). Conclusion The identified lung penetration coefficient confirms the clinical relevance of imipenem for treatment of lung infections, while the population PK model provided insights into predictors of IIV for imipenem PK and may be of relevance to support dose optimization in various subject groups. PMID:26852277

  15. Dietary predictors and plasma concentrations of perfluorinated alkyl acids in a Singapore population.

    Science.gov (United States)

    Liu, Yu; Su, Jin; van Dam, Rob M; Prem, Kiesha; Hoong, Joey Y S; Zou, Li; Lu, Yonghai; Ong, Choon Nam

    2017-03-01

    Perfluorinated alkyl acids (PFAAs), a family of man-made organofluorinated compounds, have drawn much attention due to their ubiquitous existence in the environment and their bioaccumulation potential. Here, we examined the plasma concentrations of thirteen PFAAs in a healthy population (N = 270) in Singapore, and investigated the association between major food groups and plasma PFAA concentrations. We detected eight types of PFAAs in more than 75% of all samples (N = 270), and their median concentrations ranged from 0.05 to 8.34 ng mL(-1). Age- and gender-related differences were observed for the three dominant PFAAs, i.e., perfluorooctanesulfonic acid (PFOS), perfluorohexane sulfonate (PFHxS) and perfluorooctanoate acid (PFOA), with concentrations being higher in men and older adults. Multiple linear regression analyses showed that fish, shellfish, red meat and poultry were associated with increased PFAAs concentrations in plasma, whereas grains and soy products showed inverse associations with PFAAs. Further, significant correlations were observed between various long-chain PFAAs and plasma concentrations of omega-3 fatty acids, suggesting seafood was a significant source of these PFAAs, within this population. Future studies on diet exposure to PFAAs are encouraged to focus more on the effects on diet pattern.

  16. Kinetic theory of twisted waves: Application to space plasmas having superthermal population of species

    Science.gov (United States)

    Arshad, Kashif; Poedts, Stefaan; Lazar, Marian

    2017-04-01

    ring shape morphology of a beam with orbital angular momentum (OAM) is ideal for the observation of solar corona around the sun where the intensity of the beam is minimum at the center, in solar experiments, and Earth's ionosphere. The twisted plasma modes carrying OAM are mostly studied either by the fluid theory or Maxwellian distributed Kinetic Theory. But most of the space plasmas and some laboratory plasmas have non-thermal distributions due to super-thermal population of the plasma particles. Therefore the Kinetic Theory of twisted plasma modes carrying OAM are recently studied using non-thermal (kappa) distribution of the super-thermal particles in the presence of the helical electric field and significant change in the damping rates are observed by tuning appropriate parameters.

  17. Fact Sheets

    Science.gov (United States)

    ... Fact Sheets are available in both English and Spanish and can be downloaded for free. Currently available ... Antiviral Medications to Treat or Prevent Influenza (the Flu) PDF | Espanol PDF Apremilast (Otezla®) PDF | Espanol PDF ...

  18. Assessment of a Colonoscopy Triage Sheet for Use in a Province-Wide Population-Based Colorectal Screening Program

    Directory of Open Access Journals (Sweden)

    Nour Sharara

    2016-01-01

    Full Text Available Background and Aims. A colonoscopy triage sheet (CTS integrating 6 hierarchical scheduling priorities based on indications for screening, surveillance, or symptoms was designed for colonoscopy referral. We compared CTS priority ratings by referring physicians and endoscopists, assessing yields. Methods. Retrospective study of consecutive patients. Data were collected on demographics, CTS and endoscopist priority ratings, and endoscopic findings. Weighted kappa values measured interrater agreement on priority assignment. Predictors of agreement and lesions were identified using multivariable analysis. Results. Among 1230 patients (60.3 years, 52.5% female, clinically significant lesions included tumors (1.1%, polyps per patient ≥ 10 mm (7.6%, and ileocolitis (4.6%. Moderate agreement was found between referring physician and endoscopist on all 6 priorities (weighted kappa 0.55 (0.51; 0.59. P4 and P5 ratings predicted increased agreement (range of OR for P4: 2.47–4.57; P5: 1.58–2.93. Predictors of clinically significant findings were male gender (OR 1.44, 1.03–2.03 and P1/P2 priorities that were significantly superior to P3 (OR = 2.14; 1.04–4.43, P4 (OR = 2.90; 1.35–6.23, and P5 (OR = 4.30; 2.08–8.88. Conclusion. Priority-assignment agreement is moderate and highest for less urgent ratings. Predictors of clinically significant findings validate the hierarchal priority scheme. Broader validation and physician education are needed.

  19. Plasma levels of apolipoprotein E and risk of dementia in the general population

    DEFF Research Database (Denmark)

    Rasmussen, Katrine L.; Tybjaerg-Hansen, Anne; Nordestgaard, Børge G;

    2015-01-01

    whether low plasma levels of apoE at study enrollment were associated with increased risk of future Alzheimer disease and all dementia, and whether this association was independent of ε2/ε3/ε4 APOE genotype. RESULTS: Multifactorially adjusted hazard ratios (HRs) for Alzheimer disease and all dementia......OBJECTIVE: The apolipoprotein E (APOE) ε4 allele is a major genetic risk factor for Alzheimer disease and dementia. However, it remains unclear whether plasma levels of apoE confer additional risk. We tested this hypothesis. METHODS: Using 75,708 participants from the general population, we tested...... increased from the highest to the lowest apoE tertile (p for trends dementia, respectively. After further...

  20. Plasma selenium levels and oxidative stress biomarkers: a gene-environment interaction population-based study.

    Science.gov (United States)

    Galan-Chilet, Inmaculada; Tellez-Plaza, Maria; Guallar, Eliseo; De Marco, Griselda; Lopez-Izquierdo, Raul; Gonzalez-Manzano, Isabel; Carmen Tormos, M; Martin-Nuñez, Gracia M; Rojo-Martinez, Gemma; Saez, Guillermo T; Martín-Escudero, Juan C; Redon, Josep; Javier Chaves, F

    2014-09-01

    The role of selenium exposure in preventing chronic disease is controversial, especially in selenium-repleted populations. At high concentrations, selenium exposure may increase oxidative stress. Studies evaluating the interaction of genetic variation in genes involved in oxidative stress pathways and selenium are scarce. We evaluated the cross-sectional association of plasma selenium concentrations with oxidative stress levels, measured as oxidized to reduced glutathione ratio (GSSG/GSH), malondialdehyde (MDA), and 8-oxo-7,8-dihydroguanine (8-oxo-dG) in urine, and the interacting role of genetic variation in oxidative stress candidate genes, in a representative sample of 1445 men and women aged 18-85 years from Spain. The geometric mean of plasma selenium levels in the study sample was 84.76 µg/L. In fully adjusted models the geometric mean ratios for oxidative stress biomarker levels comparing the highest to the lowest quintiles of plasma selenium levels were 0.61 (0.50-0.76) for GSSG/GSH, 0.89 (0.79-1.00) for MDA, and 1.06 (0.96-1.18) for 8-oxo-dG. We observed nonlinear dose-responses of selenium exposure and oxidative stress biomarkers, with plasma selenium concentrations above ~110 μg/L being positively associated with 8-oxo-dG, but inversely associated with GSSG/GSH and MDA. In addition, we identified potential risk genotypes associated with increased levels of oxidative stress markers with high selenium levels. Our findings support that high selenium levels increase oxidative stress in some biological processes. More studies are needed to disentangle the complexity of selenium biology and the relevance of potential gene-selenium interactions in relation to health outcomes in human populations. Copyright © 2014 Elsevier Inc. All rights reserved.

  1. Role of plasma EBV DNA levels in predicting recurrence of nasopharyngeal carcinoma in a western population

    Directory of Open Access Journals (Sweden)

    Ferrari Daris

    2012-05-01

    Full Text Available Abstract Background Loco-regionally advanced nasopharyngeal carcinomas can be cured by the combination of chemotherapy and radiotherapy. In Eastern countries, plasma levels of viral Epstein-Barr deoxyribonucleic acid (DNA are accurate in predicting recurrence, but few data are available in Western populations. The aim of this prospective study was to evaluate the relationship between viral Epstein-Barr DNA copy numbers in plasma and the response rate, progression-free survival and overall survival in a cohort of Western patients with stage IIb-IVb nasopharyngeal cancer. Methods We evaluated plasma samples from 36 consecutive patients treated with induction chemotherapy followed by chemoradiation. EBV copy numbers were determined after DNA extraction using real-time quantitative polymerase chain reaction. Survival curves were estimated using the Kaplan–Meier method. Results Circulating Epstein-Barr virus DNA levels were measured before treatment, at the end of concomitant chemo- and radiotherapy, and during the follow-up period. Pre-treatment levels significantly correlated with the initial stage and probability of relapse. Their increase was 100% specific and 71.3% sensitive in detecting loco-regional or metastatic recurrence (an overall accuracy of 94.4%. Three-year progression-free and overall survival were respectively 78.2% and 97.1%. Conclusions The results of this study confirm that patients from a Western country affected by loco-regionally advanced nasopharyngeal carcinoma have high plasma Epstein-Barr virus DNA levels at diagnosis. The monitoring of plasma levels is sensitive and highly specific in detecting disease recurrence and metastases.

  2. Discriminating between cardiac and pulmonary dysfunction in the general population with dyspnea by plasma pro-B-type natriuretic peptide

    DEFF Research Database (Denmark)

    Mogelvang, R; Goetze, JP; Schnohr, P

    2007-01-01

    OBJECTIVES: This study was designed to determine whether measurement of plasma pro-B-type natriuretic peptide (proBNP) could be used in discriminating between cardiac and pulmonary dyspnea in the general population. BACKGROUND: Natriuretic peptides are useful markers in ruling out acute cardiac...... with dyspnea, left ventricular hypertrophy and/or systolic dysfunction was associated with a 2.6-fold increase in plasma proBNP concentration (p ...% to 17%). CONCLUSIONS: In the general population with dyspnea, plasma proBNP concentrations are increased in left ventricular dilatation, hypertrophy, systolic dysfunction, or diastolic dysfunction, but are unaffected by pulmonary dysfunction....

  3. [Designing and implementation of a web-based quality monitoring system for plasma glucose measurement in multicenter population study].

    Science.gov (United States)

    Liu, Yong; Wang, Limin; Pang, Richard; Mo, Nanxun; Hu, Yan; Deng, Qian; Hu, Zhaohui

    2015-05-01

    The aim of this paper is to describe the designing and implementation of a web-based plasma glucose measurement quality monitoring system to assess the analytical quality of plasma glucose measurements in multicenter population study and provide evidence for the future studies. In the chronic non-communicable disease and related factor surveillance in China, a web based quality monitoring system for plasma glucose measurement was established to conduct evaluation on plasma glucose monitoring quality and effectiveness in 302 surveillance centers, including quality control data entry, transmission and feedback. The majority of the surveillance centers met the quality requirements and passed the evaluation of reproducibility and precision of plasma glucose measurement, only a few centers required intensive training and re-assessment. In order to ensure the completeness and reliability of plasma glucose measurement in the surveillance centers, the establishment of web-based plasma glucose measurement quality control system can facilitate the identification of the qualified surveillance centers and evaluation of plasma glucose measurement quality in different regions. Communication and training are important in ensuring plasma glucose measurement quality. It is necessary to further improve this web-based plasma glucose measurement quality monitoring system in the future to reduce the method specific plasma glucose measurement bias.

  4. Polybrominated diphenyl ethers (PBDEs) in maternal and cord blood plasma of several northern Canadian populations

    Energy Technology Data Exchange (ETDEWEB)

    Ryan, J.J. [Bureau Chemical Safety, Health Canada, Ottawa (Canada); Oostdam, J. van [Management Toxic Substances Div., Health Canada, Ottawa (Canada)

    2004-09-15

    The Northern Contaminants Program (NCP) funded by Indian and Northern Affairs Canada has carried out a number of baseline studies in Nunavut and the North West Territories of northern Canada (figure 1) to assess the exposure of indigenous peoples to a variety of chemical classes including POPs and metals. These studies, summarized by Walker et al, have used both maternal and cord human blood plasma as the media from sampling which took place in four phases over the years 1994-1999. Small amounts of individual blood plasma have remained from these investigations. We combined these individual samples into 23 composite samples of maternal and cord blood based mainly on the region and ethnicity of the donors. These composites have been used to study the exposure of northern peoples to PBDEs and to estimate, where possible, the influence of ethnicity, region of collection, and time on such exposure. Comparison is also made between the levels in plasma from northern populations and in human milk from those inhabiting the more numerous south.

  5. INTERACTION OF LASER RADIATION WITH MATTER. LASER PLASMA: Experimental optimisation of the gas-assisted laser cutting of thick steel sheets

    Science.gov (United States)

    Malikov, A. G.; Orishich, Anatolii M.; Shulyat'ev, Viktor B.

    2009-06-01

    We report on the experimental optimisation of the oxygen-assisted CO2 laser cutting of low-carbon sheet steel 5 to 25 mm in thickness. It is shown that the cut edge roughness is minimal when the energy input per unit volume of the material removed and the incident beam power per unit sheet thickness remain constant at ~20 J mm-3 and ~200 W mm-1, respectively, over the entire range of sheet thicknesses examined. The corresponding Péclet number is Pe = 0.5. These results can be used to determine the optimal beam power and cutting speed for a particular sheet thickness. At sufficiently large thicknesses, the conditions that ensure the minimum roughness can be written in the form of relations between nondimensional parameters.

  6. Partially unfolded species populated during equilibrium denaturation of the beta-sheet protein Y74W apo-pseudoazurin.

    Science.gov (United States)

    Jones, S; Reader, J S; Healy, M; Capaldi, A P; Ashcroft, A E; Kalverda, A P; Smith, D A; Radford, S E

    2000-05-16

    Apo-pseudoazurin is a single domain cupredoxin. We have engineered a mutant in which a unique tryptophan replaces the tyrosine residue found in the tyrosine corner of this Greek key protein, a region that has been proposed to have an important role in folding. Equilibrium denaturation of Y74W apo-pseudoazurin demonstrated multistate unfolding in urea (pH 7.0, 0.5 M Na(2)SO(4) at 15 degrees C), in which one or more partially folded species are populated in 4. 3 M urea. Using a variety of biophysical techniques, we show that these species, on average, have lost a substantial portion of the native secondary structure, lack fixed tertiary packing involving tryptophan and tyrosine residues, are less compact than the native state as determined by fluorescence lifetimes and time-resolved anisotropy, but retain significant residual structure involving the trytophan residue. Peptides ranging in length from 11 to 30 residues encompassing this region, however, did not contain detectable nonrandom structure, suggesting that long-range interactions are important for stabilizing the equilibrium partially unfolded species in the intact protein. On the basis of these results, we suggest that the equilibrium denaturation of Y74W apo-pseudoazurin generates one or more partially unfolded species that are globally collapsed and retain elements of the native structure involving the newly introduced tryptophan residue. We speculate on the role of such intermediates in the generation of the complex Greek key fold.

  7. Insecticide-treated plastic sheeting for emergency malaria prevention and shelter among displaced populations: an observational cohort study in a refugee setting in Sierra Leone

    NARCIS (Netherlands)

    Burns, M.R.; Rowland, M.; N'Guessan, R.; Carneiro, I.; Beeche, A.; Sesler Ruiz, S.; Kamara, S.; Takken, W.; Carnevale, P.; Allan, R.

    2012-01-01

    A double-blind phase III malaria prevention trial was conducted in two refugee camps using pre-manufactured insecticide-treated plastic sheeting (ITPS) or untreated polyethylene sheeting (UPS) randomly deployed to defined sectors of each camp. In Largo camp the ITPS or UPS was attached to inner wall

  8. Toxic metals signature in the human seminal plasma of Pakistani population and their potential role in male infertility.

    Science.gov (United States)

    Zafar, Ambreen; Eqani, Syed Ali Musstjab Akber Shah; Bostan, Nazish; Cincinelli, Alessandra; Tahir, Faheem; Shah, Syed Tahir Abbas; Hussain, Alamdar; Alamdar, Ambreen; Huang, Qingyu; Peng, Siyuan; Shen, Heqing

    2015-06-01

    Aims of this study were to provide firsthand data on the incidence of trace metals in human seminal plasma and find possible correlations between levels of toxic metals and semen quality of Pakistani population. Human semen samples were collected from male partners of couples undergoing infertility assessment at the National Institute of Health Islamabad (Pakistan). We investigated seventy-five seminal plasma samples, which were further categorized into three groups (normozoospermia, oligozoospermia and azoospermia) according to WHO guidelines. The concentration of 17 different toxic metals in human seminal plasma was determined simultaneously by using Inductively coupled plasma mass spectrometry (ICP-MS). Out of 17 trace metals, Cd and Ni showed significant difference (p metals were lower and/or comparable to that found in populations of other countries. The results show the first evidence of the effect of toxic metals on semen quality and male infertility in Pakistan.

  9. Stable isotope models of sugar intake using hair, red blood cells, and plasma, but not fasting plasma glucose, predict sugar intake in a Yup'ik study population.

    Science.gov (United States)

    Nash, Sarah H; Kristal, Alan R; Hopkins, Scarlett E; Boyer, Bert B; O'Brien, Diane M

    2014-01-01

    Objectively measured biomarkers will help to resolve the controversial role of sugar intake in the etiology of obesity and related chronic diseases. We recently validated a dual-isotope model based on RBC carbon (δ(13)C) and nitrogen (δ(15)N) isotope ratios that explained a large percentage of the variation in self-reported sugar intake in a Yup'ik study population. Stable isotope ratios can easily be measured from many tissues, including RBCs, plasma, and hair; however, it is not known how isotopic models of sugar intake compare among these tissues. Here, we compared self-reported sugar intake with models based on RBCs, plasma, and hair δ(13)C and δ(15)N in Yup'ik people. We also evaluated associations of sugar intake with fasting plasma glucose δ(13)C. Finally, we evaluated relations between δ(13)C and δ(15)N values in hair, plasma, RBCs, and fasting plasma glucose to allow comparison of isotope ratios across tissue types. Models using RBCs, plasma, or hair isotope ratios explained similar amounts of variance in total sugar, added sugar, and sugar-sweetened beverage intake (∼53%, 48%, and 34%, respectively); however, the association with δ(13)C was strongest for models based on RBCs and hair. There were no associations with fasting plasma glucose δ(13)C (R(2) = 0.03). The δ(13)C and δ(15)N values of RBCs, plasma, and hair showed strong, positive correlations; the slopes of these relations did not differ from 1. This study demonstrates that RBC, plasma, and hair isotope ratios predict sugar intake and provides data that will allow comparison of studies using different sample types.

  10. Population Inversion and Gain Measurements for Soft X-Ray Laser Development in a Magnetically Confined Plasma Column.

    Science.gov (United States)

    1985-09-01

    INVERSION AND GAIN MEASUREMENTS FOR ’I SOFT X-RAY LASER DEVELOPMENT IN A MAGNET ICALLY CONFINED PLASMA COLUMN" For the Period: Nov. 1, 1983 t hr u Sept...proposal to AFOSR entitled "Population Inversion and Gain Measurements for X-Ray Laser Development in Magnetically Confined Plasma Column," Princeton, March...I* INTRODUCTION Extensive research on x-ray laser development has provided a number of interesting results for different schemes, e.g. recombination

  11. Elevated plasma vitamin B12 levels and risk of venous thromboembolism among cancer patients: A population-based cohort study

    DEFF Research Database (Denmark)

    Arendt, Johan Frederik Håkonsen; Farkas, Dora Kormendine; Pedersen, Lars

    2017-01-01

    Introduction: Both venous thromboembolism (VTE) and high plasma vitamin B12 levels (cobalamin, Cbl) are markers of occult cancer and aggressive cancer with a poor prognosis. In this population-based cohort study, we assessed VTE risk among cancer patients with high plasma Cbl levels. Materials...... and categorised as either cancer-associated if no other provoking factors were present before VTE or provoked by other risk factors (surgery, trauma, or pregnancy). We calculated cumulative incidence proportions and adjusted hazard ratios computed from Cox regression analysis (reference: plasma Cbl of 200...

  12. Discriminating between cardiac and pulmonary dysfunction in the general population with dyspnea by plasma pro-B-type natriuretic peptide

    DEFF Research Database (Denmark)

    Mogelvang, R; Goetze, JP; Schnohr, P;

    2007-01-01

    OBJECTIVES: This study was designed to determine whether measurement of plasma pro-B-type natriuretic peptide (proBNP) could be used in discriminating between cardiac and pulmonary dyspnea in the general population. BACKGROUND: Natriuretic peptides are useful markers in ruling out acute cardiac...... the expected concentration of plasma proBNP based on age and gender was established for dyspneic subjects: an actual plasma proBNP concentration below half of the expected value ruled out left ventricular systolic and diastolic dysfunction (sensitivity 100%, 95% CI 100% to 100%; specificity 15%, 95% CI 12...

  13. Intake of up to 3 Eggs/Day Increases HDL Cholesterol and Plasma Choline While Plasma Trimethylamine-N-oxide is Unchanged in a Healthy Population.

    Science.gov (United States)

    DiMarco, Diana M; Missimer, Amanda; Murillo, Ana Gabriela; Lemos, Bruno S; Malysheva, Olga V; Caudill, Marie A; Blesso, Christopher N; Fernandez, Maria Luz

    2017-03-01

    Eggs are a source of cholesterol and choline and may impact plasma lipids and trimethylamine-N-oxide (TMAO) concentrations, which are biomarkers for cardiovascular disease (CVD) risk. Therefore, the effects of increasing egg intake (0, 1, 2, and 3 eggs/day) on these and other CVD risk biomarkers were evaluated in a young, healthy population. Thirty-eight subjects [19 men/19 women, 24.1 ± 2.2 years, body mass index (BMI) 24.3 ± 2.5 kg/m(2)] participated in this 14-week crossover intervention. Participants underwent a 2-week washout with no egg consumption, followed by intake of 1, 2, and 3 eggs/day for 4 weeks each. Anthropometric data, blood pressure (BP), dietary records, and plasma biomarkers (lipids, glucose, choline, and TMAO) were measured during each intervention phase. BMI, waist circumference, systolic BP, plasma glucose, and plasma triacylglycerol did not change throughout the intervention. Diastolic BP decreased with egg intake (P HDL cholesterol (HDL-c) (P HDL-c ratio (P HDL-c, a reduced LDL-c/HDL-c ratio, and increased plasma choline in combination with no change in plasma LDL-c or TMAO concentrations.

  14. Change of plasma visfatin level in the population with different glucose tolerances

    Institute of Scientific and Technical Information of China (English)

    杨媚

    2006-01-01

    Objective To investigate the change of plasma visfatin level and the relationship of plasma visfatin level to body mass index (BMI) , waist hip ratio (WHR) , blood glucose, plasma insulin levels as well as other factors in the subjects with different glucose tolerances. Methods Fasting and glucose loading 2 h plasma visfatin levels were assayed by ELISA in patients with type 2 diabetes

  15. T Regulatory Cells Support Plasma Cell Populations in the Bone Marrow

    Directory of Open Access Journals (Sweden)

    Arielle Glatman Zaretsky

    2017-02-01

    Full Text Available Long-lived plasma cells (PCs in the bone marrow (BM are a critical source of antibodies after infection or vaccination, but questions remain about the factors that control PCs. We found that systemic infection alters the BM, greatly reducing PCs and regulatory T (Treg cells, a population that contributes to immune privilege in the BM. The use of intravital imaging revealed that BM Treg cells display a distinct behavior characterized by sustained co-localization with PCs and CD11c-YFP+ cells. Gene expression profiling indicated that BM Treg cells express high levels of Treg effector molecules, and CTLA-4 deletion in these cells resulted in elevated PCs. Furthermore, preservation of Treg cells during systemic infection prevents PC loss, while Treg cell depletion in uninfected mice reduced PC populations. These studies suggest a role for Treg cells in PC biology and provide a potential target for the modulation of PCs during vaccine-induced humoral responses or autoimmunity.

  16. Drift modes of a quasi-two-dimensional current sheet

    Energy Technology Data Exchange (ETDEWEB)

    Artemyev, A. V.; Malova, Kh. V.; Popov, V. Yu.; Zelenyi, L. M. [Russian Academy of Sciences, Space Research Institute (Russian Federation)

    2012-03-15

    Stability of a plasma configuration consisting of a thin one-dimensional current sheet embedded into a two-dimensional background current sheet is studied. Drift modes developing in plasma as unstable waves along the current direction are considered. Dispersion relations for kink and sausage perturbation modes are obtained depending on the ratio of parameters of thin and background current sheets. It is shown that the existence of the background sheet results in a decrease in the instability growth rates and a significant increase in the perturbation wavelengths. The role of drift modes in the excitation of oscillations observed in the current sheet of the Earth's magnetotail is discussed.

  17. Plasma YKL-40 levels in healthy subjects from the general population

    DEFF Research Database (Denmark)

    Bojesen, Stig E; Johansen, Julia S; Nordestgaard, Børge G

    2011-01-01

    Plasma YKL-40 is a new biomarker in patients with cancer and inflammatory diseases. High plasma YKL-40 is associated with poor prognosis. Our aim was to determine reference levels in healthy subjects....

  18. Plasma Antenna

    OpenAIRE

    N M Vijay

    2014-01-01

    The fundamental base of plasma antenna is the use of an ionized medium as a conductor. The plasma antenna is a radiofrequency antenna formed by a plasma columns, Filaments or sheets, which are excited by a surface wave. The relevance of this device is how rapidly it can be turned on and off, only applying an electrical pulse. Besides its wide carrier frequency, the great directivity and controllable antenna shape. Otherwise a disadvantage is that it needs energy to be ionized....

  19. A Population Pharmacokinetic Model for Disposition in Plasma, Saliva and Urine of Scopolamine after Intranasal Administration to Healthy Human Subjects

    Science.gov (United States)

    Wu, L.; Tam, V. H.; Chow, D. S. L.; Putcha, L.

    2014-01-01

    An intranasal gel formulation of scopolamine (INSCOP) was developed for the treatment of Space Motion Sickness. The bioavailability and pharmacokinetics (PK) were evaluated under the Food and Drug Administration guidelines for clinical trials with an Investigative New Drug (IND) protocol. The aim of this project was to develop a PK model that can predict the relationship between plasma, saliva and urinary scopolamine concentrations using data collected from the IND clinical trials with INSCOP. Methods: Twelve healthy human subjects were administered three dose levels (0.1, 0.2 and 0.4 mg) of INSCOP. Serial blood, saliva and urine samples were collected between 5 min and 24 h after dosing and scopolamine concentrations were measured by using a validated LC-MS-MS assay. Pharmacokinetic Compartmental models, using actual dosing and sampling times, were built using Phoenix (version 1.2). Model selection was based on the likelihood ratio test on the difference of criteria (-2LL) and comparison of the quality of fit plots. Results: The best structural model for INSCOP (minimal -2LL= 502.8) was established. It consisted of one compartment each for plasma, saliva and urine, respectively, which were connected with linear transport processes except the nonlinear PK process from plasma to saliva compartment. The best-fit estimates of PK parameters from individual PK compartmental analysis and Population PK model analysis were shown in Tables 1 and 2, respectively. Conclusion: A population PK model that could predict population and individual PK of scopolamine in plasma, saliva and urine after dosing was developed and validated. Incorporating a non-linear transfer from plasma to saliva compartments resulted in a significantly improved model fitting. The model could be used to predict scopolamine plasma concentrations from salivary and urinary drug levels, allowing non-invasive therapeutic monitoring of scopolamine in space and other remote environments.

  20. Substrate-free gas-phase synthesis of graphene sheets.

    Science.gov (United States)

    Dato, Albert; Radmilovic, Velimir; Lee, Zonghoon; Phillips, Jonathan; Frenklach, Michael

    2008-07-01

    We present a novel method for synthesizing graphene sheets in the gas phase using a substrate-free, atmospheric-pressure microwave plasma reactor. Graphene sheets were synthesized by passing liquid ethanol droplets into an argon plasma. The graphene sheets were characterized by transmission electron microscopy, electron energy loss spectroscopy, Raman spectroscopy, and electron diffraction. We prove that graphene can be created without three-dimensional materials or substrates and demonstrate a possible avenue to the large-scale synthesis of graphene.

  1. Structural Biology Fact Sheet

    Science.gov (United States)

    ... Home > Science Education > Structural Biology Fact Sheet Structural Biology Fact Sheet Tagline (Optional) Middle/Main Content Area ​Other Fact Sheets What is structural biology? Structural biology is the study of how biological ...

  2. Evaluation of plasma Aβ as predictor of Alzheimer's disease in older individuals without dementia: a population-based study.

    Science.gov (United States)

    Hansson, Oskar; Stomrud, Erik; Vanmechelen, Eugeen; Östling, Svante; Gustafson, Deborah R; Zetterberg, Henrik; Blennow, Kaj; Skoog, Ingmar

    2012-01-01

    Amyloid-β (Aβ) pathology is a major component in the mechanisms behind Alzheimer's disease (AD). Measurement of Aβ(42) in cerebrospinal fluid predicts cognitive decline in patients with mild cognitive impairment and identifies AD in patients with dementia. However, studies on Aβ in plasma are contradictory. In this prospective population-based study, plasma Aβ(42) and Aβ(40) were measured at baseline in 730 adults aged 70 years or older and without dementia. After five years, plasma levels were analyzed again and participants were assessed for development of dementia. During follow-up, 53 individuals (7%) developed dementia of which 37 (5%) were classified as AD. No difference in baseline plasma Aβ(42), Aβ(40), or Aβ(42)/Aβ(40) ratio levels were observed between converters to dementia or AD compared to the cognitively stable individuals. However, individuals with plasma Aβ(40) levels above the median level for the group at baseline had an increased risk of developing dementia and AD during the follow-up, even after adjustment for age, gender, APOE genotype, and educational level (odds ratio = 2.2, 95% confidence interval = 1.0-4.7, p < 0.05). Neither plasma Aβ(42) nor the Aβ(42)/Aβ(40) ratio influenced the risk of developing dementia or AD. Moreover, Aβ(42) and Aβ(40) levels increased over the 5 years, whereas the Aβ(42)/Aβ(40) ratio decreased (p < 0.001). In conclusion, this study suggests that measurement of plasma Aβ should not be used clinically to predict dementia or AD. However, plasma Aβ(40) may possibly be regarded as a moderate risk marker comparable to other risk markers for AD such as first-degree family history of dementia.

  3. The effect of ionization on the populations of excited levels of C IV and C V in tokamak edge plasmas

    CERN Document Server

    Lawson, K D; Aggarwal, K M; Keenan, F P; Contributors, JET-EFDA; 10.1088/0953-4075/46/3/035701

    2013-01-01

    The main populating and depopulating mechanisms of the excited energy levels of ions in plasmas with densities <1023-1024 m-3 are electron collisional excitation from the ion's ground state and radiative decay, respectively, with the majority of the electron population being in the ground state of the ionization stage. Electron collisional ionization is predominately expected to take place from one ground state to that of the next higher ionization stage. However, the question arises as to whether, in some cases, ionization can also affect the excited level populations. This would apply particularly to those cases involving transient events such as impurity influxes in a laboratory plasma. An analysis of the importance of ionization in populating the excited levels of ions in plasmas typical of those found in the edge of tokamaks is undertaken for the C IV and C V ionization stages. The emphasis is on those energy levels giving rise to transitions of most use for diagnostic purposes. Carbon is chosen since...

  4. Particles and plasmas in the earth's magnetotail at 60 earth radii

    Science.gov (United States)

    Anderson, K. A.; Chase, L. M.; Lin, R. P.; Mcguire, R. E.; Mccoy, J. E.

    1974-01-01

    The main purpose of this article is to describe the plasma and particle populations in the magnetotail near 60 earth radii geocentric distance. Both the plasma sheet and the high-latitude portions of the magnetotail are discussed. Electron and proton spectra at energies above about 20 keV and electron spectra down to 0.5 keV have been obtained. Another topic of importance is the comparison of the deep magnetotail plasma sheet with the Vela satellite measurements at about 20 earth radii geocentric distance.

  5. Emtricitabine seminal plasma and blood plasma population pharmacokinetics in HIV-infected men in the EVARIST ANRS-EP 49 study.

    Science.gov (United States)

    Valade, Elodie; Tréluyer, Jean-Marc; Illamola, Silvia M; Bouazza, Naïm; Foissac, Frantz; De Sousa Mendes, Maïlys; Lui, Gabrielle; Chenevier-Gobeaux, Camille; Suzan-Monti, Marie; Rouzioux, Christine; Assoumou, Lambert; Viard, Jean-Paul; Hirt, Déborah; Urien, Saïk; Ghosn, Jade

    2015-11-01

    We aimed to describe blood plasma (BP) and seminal plasma (SP) pharmacokinetics of emtricitabine (FTC) in HIV-1-infected men, assess its penetration in the male genital tract, and evaluate its impact on seminal plasma HIV load (spVL) detection. Men from the EVARIST ANRS EP49 study receiving combined antiretroviral therapy with FTC and with suppressed BP viral load were included in the study. A total of 236 and 209 FTC BP and SP concentrations, respectively, were available. A population pharmacokinetic model was developed with Monolix 4.1.4. The impact of FTC seminal exposure on spVL detection was explored by receiver operating characteristic (ROC) curves and mixed-effects logistic regressions. FTC BP pharmacokinetics was described by a two-compartment model. The addition of an effect compartment with different input and output constants best described FTC SP pharmacokinetics. No covariates were found to explain the variability in SP. FTC exposures (area under the concentration-time curve from 0 to 24 h [AUC0-24]) were higher in SP than in BP (median AUC0-24, 38.04 and 12.95 mg · liter(-1) · h, respectively). The median (range) SP-to-BP AUC0-24 ratio was 2.91 (0.84 to 10.08). Less than 1% of FTC AUC0-24 ratios were lower than 1. The impact of FTC SP AUC0-24 or FTC SP-to-BP AUC0-24 ratio on spVL detection was not significant (P = 0.943 or 0.893, respectively). This is the first population model describing FTC pharmacokinetics simultaneously in both BP and SP. FTC distributes well in the male genital tract with higher FTC concentrations in SP than in BP. FTC seminal plasma exposures were considered efficient in the majority of men.

  6. Analysis of propagation prop erties of electromagnetic waves through large planar plasma sheets%电磁波在大面积等离子体片中传播特性的分析∗

    Institute of Scientific and Technical Information of China (English)

    夏俊明; 徐跃民; 孙越强; 霍文青; 孙海龙; 白伟华; 柳聪亮; 孟祥广

    2015-01-01

    Large planar plasma sheets, generated by a linear hollow cathode in pulse discharge mode under magnetic con-finement, can be used in the field of plasma antenna, plasma stealth, and simulation of a plasma layer surrounding vehicles traveling at hypersonic velocities within the Earth’s atmosphere. Firstly, to investigate the propagation prop-erties of electromagnetic waves at different frequencies and polarization, the transverse field transfer matrix method is introduced. Secondly, the measured electron density temporal and spatial distribution and the transverse field transfer matrix method are utilized to calculate the reflection, transmission and absorption of electromagnetic waves by large planar plasma sheets with different currents. Finally, 1 GHz (less than the critical cut-off frequency) electromagnetic waves and 4 GHz (greater than the critical frequency) electromagnetic waves are chosen to investigate the evolution of propagation properties during the pulsed discharge period. Results show that both the reflection and absorption of the electromagnetic waves are greater for their polarization direction parallel to that of magnetic field, and their frequencies lower than the critical cut-off frequency, and as the discharge currents rise, the reflection increases while the absorption decreases. However both the reflection and absorption of the electromagnetic waves with their polarization direction perpendicular to the magnetic field direction and their frequency greater than the critical cut-off frequency become less, and as the discharge currents rise, both the reflection and absorption will increase. For the electromagnetic waves with their polarization direction perpendicular to the magnetic field direction, there is an upper hybrid resonance absorption band near the upper hybrid resonance frequencies, in which the absorption is significant but the absorption peak value is not affected by the discharge current. The propagation characteristics of the

  7. Association of Plasma Heat Shock Protein 70, Interleukin 6, and Creatine Kinase Concentrations in a Healthy, Young Adult Population

    Directory of Open Access Journals (Sweden)

    Carmen Contreras-Sesvold

    2015-01-01

    Full Text Available Variations of baseline plasma concentrations of creatine kinase (CK, heat shock protein 70 (HSP70, and interleukin 6 (IL-6 have been reported. We report categorical associations which may influence these protein levels. Methods. Blood was harvested for DNA and plasma protein analysis from 567 adults. Mean protein levels of CK, HSP70, and IL-6 were compared by sex, ethnicity, genetic variants—CKMM Nco1 (rs1803285, HSPA1B +A1538G (rs1061581, and IL6 G-174C (rs1800795—self-reported history of exercise, oral contraceptive use, and dietary supplement use. Results. SNP major allele frequencies for CKMM, HSPA1B, and IL6 were 70% A, 57% A, and 60%. Mean CK statistically differed by sex, ethnicity, oral contraceptives, and caffeine. Plasma HSP70 differed by caffeine and protein. Mean IL-6 concentration differed by sex, ethnicity, and genotype. Plasma IL-6 was significantly lower (29% in males (1.92 ± 0.08 pg/mL and higher (29% among African Americans (2.85 ± 0.50 pg/mL relative to the others. IL6 G-174C GG genotype (2.23 ± 0.14 pg/mL was 19% greater than CG or CC genotypes. Conclusion. Differences in baseline CK and IL-6 plasma protein concentrations are associated with genetics, sex, ethnicity, and the use of oral contraceptives, caffeine, and protein supplements in this young and athletic population.

  8. Plasma lutein and zeaxanthin and the risk of age-related nuclear cataract among the elderly Finnish population.

    Science.gov (United States)

    Karppi, Jouni; Laukkanen, Jari A; Kurl, Sudhir

    2012-07-14

    Oxidative stress plays an important role in cataractogenesis. Previous studies have shown that long-term dietary intake of antioxidants (lutein and zeaxanthin) may decrease the risk of age-related cataracts. The aim of the present study was to examine whether plasma concentrations of lutein and zeaxanthin are related to age-related nuclear cataract in the elderly population. Subjects were participants in the Kuopio Ischaemic Heart Disease Risk Factor Study and they were classified into tertiles according to plasma concentrations of lutein and zeaxanthin. The association of plasma lutein and zeaxanthin concentrations with age-related nuclear cataract in 1689 elderly subjects (aged 61-80 years) was investigated in the present cross-sectional study by using the Cox proportional hazards model. A total of 113 cases of incident age-related cataracts were confirmed, of which 108 cases were nuclear cataracts. After adjustment for age, examination year, sex, BMI, smoking, alcohol consumption, serum LDL-cholesterol, serum HDL-cholesterol, years of education, use of oral corticosteroids, history of diabetes and history of hypertension with current use of antihypertensive medication, subjects in the highest tertiles of plasma concentrations of lutein and zeaxanthin had 42 and 41 % lower risks of nuclear cataract, respectively, compared with those in the lowest tertiles (relative risk (RR) = 0·58, 95 % CI 0·35, 0·98; P = 0·041 for lutein and RR = 0·59, 95 % CI 0·35, 0·99; P = 0·046 for zeaxanthin). In conclusion, we suggest that high plasma concentrations of lutein and zeaxanthin were associated with a decreased risk of age-related nuclear cataract in the elderly population.

  9. Non-thermal electron populations in microwave heated plasmas investigated with X-ray detectors

    Energy Technology Data Exchange (ETDEWEB)

    Belapure, Jaydeep Sanjay

    2013-04-15

    An investigation of the generation and dynamics of superthermal electrons in fusion plasma is carried out. A SDD+CsI(Tl) based X-ray diagnostic is constructed, characterized and installed at ASDEX Upgrade. In various plasma heating power and densities, the fraction and the energy distribution of the superthermal electrons is obtained by a bi-Maxwellian model and compared with Fokker-Planck simulations.

  10. Energy spectra of plasma sheet ions and electrons from about 50 eV/e to about 1 MeV during plamsa temperature transitions

    Science.gov (United States)

    Christon, S. P.; Mitchell, D. G.; Williams, D. J.; Frank, L. A.; Huang, C. Y.; Eastman, T. E.

    1988-01-01

    ISEE-1 charged-particle measurements obtained during eight plasma temperature transitions (PTTs) in 1978-1979 are compiled in tables and graphs and analyzed in detail, comparing the ion and electron differential energy spectra with the predictions of theoretical models. PTTs are defined as approximately 1-h periods of low bulk plasma velocity and steadily increasing or decreasing thermal energy. A Maxwellian distribution is found to be inadequate in describing the PTT energy spectra, but velocity-exponential and kappa distributions are both successful, the latter especially at higher energies. The power-law index kappa varies from PTT to PTT, but the high-energy spectral index and overall shape of the distribution remain constant during a PTT; both spatial and temporal effects are observed.

  11. Effect of pulsed current micro plasma arc welding process parameters on fusion zone grain size and ultimate tensile strength of Inconel 625 sheets

    Institute of Scientific and Technical Information of China (English)

    Kondapalli Siva Prasad; Chalamalasetti Srinivasa Rao; Damera Nageswara Rao

    2012-01-01

    The paper focuses on developing mathematical models to predict grain size and ultimate tensile strength of pulsed current micro plasma arc welded Inconel 625 nickel alloy.Four factors,five levels,central composite rotatable design matrix is used to optimize the number of experiments.The mathematical models have been developed by response surface method.The adequacy of the models is checked by analysis of variance technique.By using the developed mathematical models,grain size and ultimate tensile strength of the joints can be predicted with 99%0 confidence level.Contour plots are drawn to study the interaction effect of pulsed current micro plasma arc welding parameters on fusion zone grain size and ultimate tensile strength of Inconel 625 weld ioints.

  12. Plasma Adiponectin Concentrations and Adiponectin Gene Polymorphisms Are Associated with Bronchial Asthma in the Chinese Li Population

    Directory of Open Access Journals (Sweden)

    Yipeng Ding

    2015-10-01

    Full Text Available The purpose of this study was to determine the clinical significance of changes in the plasma  adiponectin  concentration  in  patients  with  bronchial  asthma  and  to  test  the association between the single nucleotide polymorphisms (SNPs rs2241766 and rs1501299 in the ADIPOQ gene and bronchial asthma in the Chinese Li population.We selected 120 cases and 120 controls, and plasma adiponectin, interleukin (IL-6, and tumor  necrosis  factor-alpha  (TNF-α  levels  were  measured  by  enzyme-linked immunosorbent assay (ELISA. In addition, we genotyped two tag single nucleotide polymorphisms (tSNPs and evaluated their association with bronchial asthma using the χ2 test and genetic model analysis.Compared to controls, patients with acute exacerbation of bronchial asthma showedsignificantly lower adiponectin and significantly higher IL-6 and TNF-α levels (p<0.01. Apositive association was found between the rs1501299 SNP and acute exacerbation (OR =1.62; 95% CI= 1.08-2.43; p= 0.019.The inverse correlation between the plasma adiponectin concentration and asthma exacerbation indicates that adiponectin may play a protective role in the pathogenesis of asthma. Meanwhile, our findings suggest that ADIPOQ polymorphisms influence the risk of developing bronchial asthma in Chinese Li population.

  13. Population plasma and urine pharmacokinetics of ivabradine and its active metabolite S18982 in healthy Korean volunteers.

    Science.gov (United States)

    Choi, Hee Youn; Bae, Kyun-Seop; Cho, Sang-Heon; Ghim, Jong-Lyul; Choe, Sangmin; Jung, Jin Ah; Lim, Hyeong-Seok

    2016-04-01

    Ivabradine, a selective inhibitor of the pacemaker current (If ), is used for heart failure and coronary heart disease and is mainly metabolized to S18982. The purpose of this study was to explore the pharmacokinetics (PK) of ivabradine and S18982 in healthy Korean volunteers. Subjects in a phase I study were randomized to receive 2.5, 5, or 10 mg of ivabradine administered every 12 hours for 4.5 days, and serial plasma and urine concentrations of ivabradine and S18982 were measured. The plasma PK of ivabradine was best described by a 2-compartment model with mixed 0- and first-order absorption, linked to a 2-compartment model for S18982. The introduction of interoccasional variabilities and period as covariate into absorption-related parameters improved the model fit. Urine data have been applied to estimate renal and nonrenal clearance, enabling a more detailed description of the elimination process. We developed a population PK model describing the plasma and urine PK of ivabradine and S18982 in healthy Korean adult males. This model might be useful for predicting the plasma and urine PK of ivabradine, potentially helping to identify the optimal dosing regimens in various clinical situations.

  14. Resting venous plasma adrenalin in 70-year-old men correlated positively to survival in a population study: the significance of the physical working capacity

    DEFF Research Database (Denmark)

    Christensen, Niels Juel; Schultz-Larsen, K

    1994-01-01

    OBJECTIVE. The aim of the study was to evaluate plasma noradrenaline (NA) and plasma adrenalin (A) as predictors of mortality in a population study. SUBJECTS. All subjects were 70 years of age in 1984. They were selected from the National Person Register. Altogether, 804 subjects participated...

  15. Heliospheric plasma sheet (HPS) impingement onto the magnetosphere as a cause of relativistic electron dropouts (REDs) via coherent EMIC wave scattering with possible consequences for climate change mechanisms

    Science.gov (United States)

    Tsurutani, B. T.; Hajra, R.; Tanimori, T.; Takada, A.; Bhanu, R.; Mannucci, A. J.; Lakhina, G. S.; Kozyra, J. U.; Shiokawa, K.; Lee, L. C.; Echer, E.; Reddy, R. V.; Gonzalez, W. D.

    2016-10-01

    A new scenario is presented for the cause of magnetospheric relativistic electron decreases (REDs) and potential effects in the atmosphere and on climate. High-density solar wind heliospheric plasmasheet (HPS) events impinge onto the magnetosphere, compressing it along with remnant noon-sector outer-zone magnetospheric 10-100 keV protons. The betatron accelerated protons generate coherent electromagnetic ion cyclotron (EMIC) waves through a temperature anisotropy (T⊥/T|| > 1) instability. The waves in turn interact with relativistic electrons and cause the rapid loss of these particles to a small region of the atmosphere. A peak total energy deposition of 3 × 1020 ergs is derived for the precipitating electrons. Maximum energy deposition and creation of electron-ion pairs at 30-50 km and at Wilcox et al. (1973) noted a correlation between solar wind heliospheric current sheet (HCS) crossings and high atmospheric vorticity centers at 300 mb altitude. Tinsley et al. has constructed a global circuit model which depends on particle precipitation into the atmosphere. Other possible scenarios potentially affecting weather/climate change are also discussed.

  16. Insecticide-treated plastic sheeting for emergency malaria prevention and shelter among displaced populations: an observational cohort study in a refugee setting in Sierra Leone.

    Science.gov (United States)

    Burns, Matthew; Rowland, Mark; N'guessan, Raphael; Carneiro, Ilona; Beeche, Arlyne; Ruiz, Stefani Sesler; Kamara, Sarian; Takken, Willem; Carnevale, Pierre; Allan, Richard

    2012-08-01

    A double-blind phase III malaria prevention trial was conducted in two refugee camps using pre-manufactured insecticide-treated plastic sheeting (ITPS) or untreated polyethylene sheeting (UPS) randomly deployed to defined sectors of each camp. In Largo camp the ITPS or UPS was attached to inner walls and ceilings of shelters, whereas in Tobanda the ITPS or UPS was used to line only the ceiling and roof. In Largo the Plasmodium falciparum incidence rate in children up to 3 years of age who were cleared of parasites and monitored for 8 months was 163/100 person-years under UPS and 63 under ITPS (adjusted odds ratio [AOR] = 0.40, 95% confidence interval [CI] = 0.33-0.47). In Tobanda incidence was 157/100 person-years under UPS and 134 under ITPS (AOR = 0.85, 95% CI = 0.75-0.95). Protective efficacy was 61% under fully lined ITPS and 15% under roof lined ITPS. Anemia rates improved under ITPS in both camps. This novel tool proved to be a convenient, safe, and long-lasting method of malaria control when used as a full shelter lining in an emergency setting.

  17. Reconnection in thin current sheets

    Science.gov (United States)

    Tenerani, Anna; Velli, Marco; Pucci, Fulvia; Rappazzo, A. F.

    2016-05-01

    It has been widely believed that reconnection is the underlying mechanism of many explosive processes observed both in nature and laboratory, but the question of reconnection speed and initial trigger have remained mysterious. How is fast magnetic energy release triggered in high Lundquist (S) and Reynolds (R) number plasmas?It has been shown that a tearing mode instability can grow on an ideal timescale, i.e., independent from the the Lundquist number, once the current sheet thickness becomes thin enough, or rather the inverse aspect ratio a/L reaches a scale a/L~S-1/3. As such, the latter provides a natural, critical threshold for current sheets that can be formed in nature before they disrupt in a few Alfvén time units. Here we discuss the transition to fast reconnection extended to simple viscous and kinetic models and we propose a possible scenario for the transition to explosive reconnection in high-Lundquist number plasmas, that we support with fully nonlinear numerical MHD simulations of a collapsing current sheet.

  18. Central and peripheral blood pressures in relation to plasma advanced glycation end products in a Chinese population.

    Science.gov (United States)

    Huang, Q-F; Sheng, C-S; Kang, Y-Y; Zhang, L; Wang, S; Li, F-K; Cheng, Y-B; Guo, Q-H; Li, Y; Wang, J-G

    2016-07-01

    We investigated the association of plasma AGE (advanced glycation end product) concentration with central and peripheral blood pressures and central-to-brachial blood pressure amplification in a Chinese population. The study subjects were from a newly established residential area in the suburb of Shanghai. Using the SphygmoCor system, we recorded radial arterial waveforms and derived aortic waveforms by a generalized transfer function and central systolic and pulse pressure by calibration for brachial blood pressure measured with an oscillometric device. The central-to-brachial pressure amplification was expressed as the central-to-brachial systolic blood pressure difference and pulse pressure difference and ratio. Plasma AGE concentration was measured by the enzyme-linked immunosorbent assay method and logarithmically transformed for statistical analysis. The 1051 participants (age, 55.1±13.1 years) included 663 women. After adjustment for sex, age and other confounding factors, plasma AGE concentration was associated with central but not peripheral blood pressures and with some of the pressure amplification indexes. Indeed, each 10-fold increase in plasma AGE concentration was associated with 2.94 mm Hg (P=0.04) higher central systolic blood pressure and 2.39% lower central-to-brachial pulse pressure ratio (P=0.03). In further subgroup analyses, the association was more prominent in the presence of hypercholesterolemia (+8.11 mm Hg, P=0.008) for central systolic blood pressure and in the presence of overweight and obesity (-4.89%, P=0.009), diabetes and prediabetes (-6.26%, P=0.10) or current smoking (-6.68%, P=0.045) for central-to-brachial pulse pressure ratio. In conclusion, plasma AGE concentration is independently associated with central systolic blood pressure and pulse pressure amplification, especially in the presence of several modifiable cardiovascular risk factors.

  19. Impact of hemoglobin on plasma pro-B-type natriuretic peptide concentrations in the general population

    DEFF Research Database (Denmark)

    Nybo, Mads; Benn, Marianne; Mogelvang, Rasmus

    2007-01-01

    Age, sex, and renal function contribute to variations in plasma concentrations of B-type natriuretic peptide (BNP) and its molecular precursor (proBNP). Recent studies indicate that anemia may also affect proBNP concentrations in patients with heart failure or stroke. However, the impact...

  20. Elucidating the Plasma and Liver Pharmacokinetics of Simeprevir in Special Populations Using Physiologically Based Pharmacokinetic Modelling.

    Science.gov (United States)

    Snoeys, Jan; Beumont, Maria; Monshouwer, Mario; Ouwerkerk-Mahadevan, Sivi

    2016-11-29

    The disposition of simeprevir (SMV) in humans is characterised by cytochrome P450 3A4 metabolism and hepatic uptake by organic anion transporting polypeptide 1B1/3 (OATP1B1/3). This study was designed to investigate SMV plasma and liver exposure upon oral administration in subjects infected with hepatitis C virus (HCV), in subjects of Japanese or Chinese origin, subjects with organ impairment and subjects with OATP genetic polymorphisms, using physiologically based pharmacokinetic modelling. Simulations showed that compared with healthy Caucasian subjects, SMV plasma exposure was 2.4-, 1.7-, 2.2- and 2.0-fold higher, respectively, in HCV-infected Caucasian subjects, in healthy Japanese, healthy Chinese and subjects with severe renal impairment. Further simulations showed that compared with HCV-infected Caucasian subjects, SMV plasma exposure was 1.6-fold higher in HCV-infected Japanese subjects. In subjects with OATP1B1 genetic polymorphisms, no noteworthy changes in SMV pharmacokinetics were observed. Simulations suggested that liver concentrations in Caucasians with HCV are 18 times higher than plasma concentrations.

  1. Zika Virus Fact Sheet

    Science.gov (United States)

    ... sheets Fact files Questions & answers Features Multimedia Contacts Zika virus Fact sheet Updated 6 September 2016 Key ... and last for 2-7 days. Complications of Zika virus disease Based on a systematic review of ...

  2. Trauma Fact Sheet

    Science.gov (United States)

    ... Home > Science Education > Physical Trauma Fact Sheet Physical Trauma Fact Sheet Tagline (Optional) Middle/Main Content Area ... of physical trauma. Credit: iStock. What is physical trauma? Physical trauma is a serious injury to the ...

  3. Diabetes Fact Sheet

    Science.gov (United States)

    ... diabetes by losing weight. Related information Fitness and nutrition Heart disease and stroke Obesity and weight loss fact sheet Physical activity fact sheet Pregnancy The javascript used in this widget is not ...

  4. Determinants of plasma pepsinogen levels in a population at high risk for stomach cancer in Venezuela.

    Science.gov (United States)

    Kato, I; Miki, K; Muñoz, N; Vivas, J H; Lopez, G; Peraza, S; Carillo, E; Castro, D; Andrade, O; Sanchez, V

    1995-09-04

    Determinants of plasma pepsinogens (PG) levels were studied in 1365 participants in a chemoprevention trial for gastric pre-cancerous lesions being conducted in Venezuela. Gastric biopsies, plasma samples and information on smoking and dietary habits were obtained at baseline examination. Both PG-I and PG-II levels increased progressively with the level of Helicobacter pylori infection in gastric biopsies, resulting in no clear trend in the I/II ratio. Instead, there was a progressive decrease in the I/II ratio with increasing degrees of infiltration of polynuclear cells and monocytes, atrophy, intestinal metaplasia and the stage of pre-cancerous lesions. The mean I/II ratios for atrophic gastritis or more advanced lesions were less than 4.0. When subjects with the I/II ratio 4 or higher were used as controls, severe reduction in the I/II ratio (food on the development of atrophic gastritis need to be studied further.

  5. Impact of hemoglobin on plasma pro-B-type natriuretic peptide concentrations in the general population

    DEFF Research Database (Denmark)

    Nybo, Mads; Benn, Marianne; Mogelvang, Rasmus

    2007-01-01

    BACKGROUND: Age, sex, and renal function contribute to variations in plasma concentrations of B-type natriuretic peptide (BNP) and its molecular precursor (proBNP). Recent studies indicate that anemia may also affect proBNP concentrations in patients with heart failure or stroke. However...... the proBNP plasma concentration. RESULTS: The mean proBNP concentration was increased 1.7-fold in the group with anemia vs the nonanemic group [mean (SD) 42 (45) pmol/L vs 25 (29) pmol/L, P ... was modest. CONCLUSIONS: Because moderate anemia is associated with a 1.7-fold increase in proBNP concentrations, hemoglobin concentrations should be taken into consideration in patients with nonspecific symptoms of heart disease and increased proBNP concentrations....

  6. First Results from ARTEMIS, a New Two-Spacecraft Lunar Mission: Counter-Streaming Plasma Populations in the Lunar Wake

    Science.gov (United States)

    Halekas, J. S.; Angelopoulos, V.; Sibeck, D. G.; Khurana, K. K.; Russell, C. T.; Delory, G. T.; Farrell, W. M.; McFadden, J. P.; Bonnell, J. W.; Larson, D.; Ergun, R. E.; Plaschke, F.; Glassmeier, K. H.

    2011-12-01

    We present observations from the first passage through the lunar plasma wake by one of two spacecraft comprising ARTEMIS (Acceleration, Reconnection, Turbulence, and Electrodynamics of the Moon's Interaction with the Sun), a new lunar mission that re-tasks two of five probes from the THEMIS magnetospheric mission. On Feb 13, 2010, ARTEMIS probe P1 passed through the wake at ˜3.5 lunar radii downstream from the Moon, in a region between those explored by Wind and the Lunar Prospector, Kaguya, Chandrayaan, and Chang'E missions. ARTEMIS observed interpenetrating proton, alpha particle, and electron populations refilling the wake along magnetic field lines from both flanks. The characteristics of these distributions match expectations from self-similar models of plasma expansion into vacuum, with an asymmetric character likely driven by a combination of a tilted interplanetary magnetic field and an anisotropic incident solar wind electron population. On this flyby, ARTEMIS provided unprecedented measurements of the interpenetrating beams of both electrons and ions naturally produced by the filtration and acceleration effects of electric fields set up during the refilling process. ARTEMIS also measured electrostatic oscillations closely correlated with counter-streaming electron beams in the wake, as previously hypothesized but never before directly measured. These observations demonstrate the capability of the comprehensively instrumented ARTEMIS spacecraft and the potential for new lunar science from this unique two spacecraft constellation.

  7. First Results from ARTEMIS, A New Two-Spacecraft Lunar Mission: Counter-Streaming Plasma Populations in the Lunar Wake

    Science.gov (United States)

    Halekas, J. S.; Angelopoulos, V.; Sibeck, D. G.; Khurana, K. K.; Russell, C. T.; Delory, G. T.; Farrell, W. M.; McFadden, J. P.; Bonnell, J. W.; Larson, D.; Ergun, R. E.; Plaschke, F.; Glassmeier, K. H.

    2014-01-01

    We present observations from the first passage through the lunar plasma wake by one of two spacecraft comprising ARTEMIS (Acceleration, Reconnection, Turbulence, and Electrodynamics of the Moon's Interaction with the Sun), a new lunar mission that re-tasks two of five probes from the THEMIS magnetospheric mission. On Feb 13, 2010, ARTEMIS probe P1 passed through the wake at approximately 3.5 lunar radii downstream from the Moon, in a region between those explored by Wind and the Lunar Prospector, Kaguya, Chandrayaan, and Chang'E missions. ARTEMIS observed interpenetrating proton, alpha particle, and electron populations refilling the wake along magnetic field lines from both flanks. The characteristics of these distributions match expectations from self-similar models of plasma expansion into vacuum, with an asymmetric character likely driven by a combination of a tilted interplanetary magnetic field and an anisotropic incident solar wind electron population. On this flyby, ARTEMIS provided unprecedented measurements of the interpenetrating beams of both electrons and ions naturally produced by the filtration and acceleration effects of electric fields set up during the refilling process. ARTEMIS also measured electrostatic oscillations closely correlated with counter-streaming electron beams in the wake, as previously hypothesized but never before directly measured. These observations demonstrate the capability of the comprehensively instrumented ARTEMIS spacecraft and the potential for new lunar science from this unique two spacecraft constellation.

  8. First Results from ARTEMIS, A New Two-Spacecraft Lunar Mission: Counter-Streaming Plasma Populations in the Lunar Wake

    Science.gov (United States)

    Halekas, J. S.; Angelopoulos, V.; Sibeck, D. G.; Khurana, K. K.; Russell, C. T.; Delory, G. T.; Farrell, W. M.; McFadden, J. P.; Bonnell, J. W.; Larson, D.; hide

    2014-01-01

    We present observations from the first passage through the lunar plasma wake by one of two spacecraft comprising ARTEMIS (Acceleration, Reconnection, Turbulence, and Electrodynamics of the Moon's Interaction with the Sun), a new lunar mission that re-tasks two of five probes from the THEMIS magnetospheric mission. On Feb 13, 2010, ARTEMIS probe P1 passed through the wake at approximately 3.5 lunar radii downstream from the Moon, in a region between those explored by Wind and the Lunar Prospector, Kaguya, Chandrayaan, and Chang'E missions. ARTEMIS observed interpenetrating proton, alpha particle, and electron populations refilling the wake along magnetic field lines from both flanks. The characteristics of these distributions match expectations from self-similar models of plasma expansion into vacuum, with an asymmetric character likely driven by a combination of a tilted interplanetary magnetic field and an anisotropic incident solar wind electron population. On this flyby, ARTEMIS provided unprecedented measurements of the interpenetrating beams of both electrons and ions naturally produced by the filtration and acceleration effects of electric fields set up during the refilling process. ARTEMIS also measured electrostatic oscillations closely correlated with counter-streaming electron beams in the wake, as previously hypothesized but never before directly measured. These observations demonstrate the capability of the comprehensively instrumented ARTEMIS spacecraft and the potential for new lunar science from this unique two spacecraft constellation.

  9. Plasma Plasminogen Activator Inhibitor-1 Is Associated with End-Stage Proliferative Diabetic Retinopathy in the Northern Chinese Han Population

    Directory of Open Access Journals (Sweden)

    Ze-Long Zhong

    2012-01-01

    Full Text Available Objective. To identify predictors of end-stage proliferative diabetic retinopathy (PDR in a cohort of individuals with type 2 diabetes mellitus (T2DM from the Northern Chinese Han population. Methods. We investigated characteristics of 153 consecutive diabetic patients with end-stage PDR (62 males, 91 females, 123 consecutive PDR patients without end-stage PDR (48 males, 75 females, and 151 normal subjects (63 males, 88 females. Only one eye of each patient or healthy subject was included in this study. Univariate logistic regression models and multivariate logistic regression models were constructed to evaluate the predictors of end-stage PDR. Results. In univariate analysis, systolic blood pressure, diastolic blood pressure, duration of diabetes, family history of T2DM, and plasminogen activator inhibitor-1 (PAI-1 were significently associated with end-stage PDR. After multivariate analysis, family history of T2DM, plasma PAI-1 levels, smoking, and duration of diabetes were four positive predictors associated with end-stage PDR. Conclusions. Higher plasma levels of PAI-1 were associated with end-stage PDR in the Northern Chinese Han population with T2DM.

  10. PCDD/F levels in plasma of a belgian population before and after the 1999 belgian PCB/DIOXIN incident.

    Science.gov (United States)

    Debacker, Noëmi; Sasse, André; van Wouwe, Nathalie; Goeyens, Leo; Sartor, Francis; van Oyen, Herman

    2007-04-01

    We evaluated the impact of the 1999 Belgian dioxin incident on the blood plasma polychlorinated dibenzo-p-dioxin (PCDD) and polychlorinated dibenzofuran (PCDF) levels among 232 Belgian blood donors (74% men, mean age 47 years). The Red Cross made plasma samples from before the incident of these donors available. A second plasma sample was collected during the second half of 2000. The sum of the 17 PCDD/F congeners was significantly lower in 2000 compared to 1998 (417 pg/g fat versus 445 pg/g fat, respectively). This could be completely attributed to the significant decrease of OctaCDD (301 pg/g fat in 2000 versus 277 pg/g fat in 1998). Moreover a slight but significant decrease was observed for 2,3,7,8-TetraCDF and for 1,2,3,4,6,7,8-HeptaCDF. 1,2,3,7,8-PentaCDF and 2,3,4,7,8-PentaCDF however showed a slight but significant increase (respective levels in 1998 were 0.004 and 14.5 pg/g fat compared to 0.006 and 17.9 pg/g fat in 2000). Given their significantly higher presence in incident related food samples this increase can be attributed to the food contamination episode. However, the total toxicity remained unchanged (22.9 in 1998 versus 23.1 pg WHO-TEQ/g fat, p>0.05). Moreover the observed congener profiles and the total PCDD/F levels were similar to those of other European non-occupationally exposed populations. In conclusion, the 1999 PCB/dioxin incident was traceable in the plasma profiles (rise of the two specific PCDF congeners), but comparison of the results for both years indicates that the changes were too small to cause an adverse public health effect.

  11. Relationship between seminal plasma zinc and semen quality in a subfertile population

    Directory of Open Access Journals (Sweden)

    DMAB Dissanayake

    2010-01-01

    Full Text Available Rationale : Current knowledge on the relationship between seminal zinc levels and different parameters of human semen is inconsistent. Objectives : To assess the relationship between seminal plasma zinc and semen quality using two markers; zinc concentration (Zn-C and total zinc per ejaculate (Zn-T. Design : The study was carried out as a cross-sectional study. Subjects and Methods : Semen parameters of 152 healthy men undergoing evaluation for subfertility were assessed. Seminal plasma zinc levels were determined using flame atomic absorption spectrometry. Zn-C, expressed as μg/mL, was multiplied by ejaculated volume to calculate Zn-T. Mann Whitney U test and Chi-square test were used to compare the zinc levels between different seminal groups when appropriate. Correlations were observed with Pearson′s correlation of coefficient. Analysis was carried out using SPSS 10.0 for windows software. Results : Zn-C was low in 23 (15% samples, while in 32 (21% of the samples Zn-T was abnormal. The number of subnormal samples was high in the low-zinc groups compared with the normal-zinc groups, 15 vs. 8 (P > 0.05 for Zn-C and 28 vs. 4 (P < 0.001 for Zn-T. Zn-C was significantly high in the asthenozoospermics compared with the normal motile group; 138.11 μg/mL (83.92 vs. 110.69 11 μg/mL (54.59 (P < 0.05. Zn-T was significantly low in samples with hyperviscosity compared with samples with normal viscosity; 220.06 μg (144.09 vs. 336.34 μg (236.33 (P < 0.05. Conversely, Zn-T was high in samples with low viability compared with those with normal viability; 437.67 μg (283.88 vs. 305.15 μg (221.19 (P < 0.05. Weak correlations were found between Zn and some semen parameters. However, the correlation was negative between pH and Zn-C (r = -0.193, P < 0.05 as well as Zn-T (r = -0.280, P < 0.01. On the other hand, correlations were positive between Zn-T and sperm count (r = 0.211, P < 0.05. Conclusion : Count, motility, viability, pH and viscosity are

  12. Plasma levels of apolipoprotein E and risk of ischemic heart disease in the general population

    DEFF Research Database (Denmark)

    Rasmussen, Katrine L.; Tybjærg-Hansen, Anne; Nordestgaard, Børge G

    2016-01-01

    BACKGROUND AND AIMS: Triglyceride-rich lipoproteins are causally associated with high risk of ischemic heart disease (IHD), and apolipoprotein E (apoE) has a central role in their plasma clearance. While both quantitative and qualitative changes of apoE are established causes of rare dyslipidemia....... RESULTS: Multifactorially adjusted hazard ratios (HRs) for highest versus lowest apoE tertile were 1.15 (1.04-1.27) for IHD and 1.16 (1.00-1.36) for MI in men, and 0.94 (0.84-1.05) and 1.04 (0.85-1.26) in women. These associations were attenuated by adjustments for triglyceride levels. Corresponding HRs......E are associated with IHD in men but not in women. Triglyceride-rich lipoproteins may partly explain these associations....

  13. Reference interval determination of total plasma homocysteine in an Indian population.

    Science.gov (United States)

    Lahiri, Kapil D; Datta, Himadri; Das, Harendra N

    2014-01-01

    Hyperhomocysteinemia has been shown to be an independent risk factor for cardiovascular disease as well as retinal vascular occlusion. Because of the epidemiological, dietary, genetic and environmental diversity among the different countries, each country should establish the reference interval of homocysteine of their own population for recommending appropriate medical decision limits. Hence a total of 1,288 apparently healthy subjects including 636 male and 652 female were enrolled in the present study to determine the reference intervals of homocysteine in an Indian population. Results of the study were presented as mean, standard deviation, median and 2.5th and 97.5th percentile with the 0.90 confidence interval of each percentile values of homocysteine along with decade-wise changes.

  14. Population densities of hydrogenlike ions in a non-Maxwellian plasma.

    Science.gov (United States)

    Ashbourn, J M

    2001-04-01

    In this paper we examine the effects of non-Maxwellian electron energy distributions on the population densities of excited atomic levels for hydrogenlike ions. We model the electron energy distribution function by two Maxwellian finite elements, one approximating the bulk distribution with temperature T(b) and the other the tail distribution with temperature T(t). We present results for various T(b)/T(t) ratios for Si XIV.

  15. Model for describing non-equilibrium helium plasma energy level population

    Science.gov (United States)

    Kavyrshin, D. I.; Chinnov, V. F.; Ageev, A. G.

    2015-11-01

    A new method for calculating the population of excited levels of helium atoms and ions is suggested. The method is based on direct solution of a system of balance equations for all energy levels for which it was possible to obtain process speed constants. The equations include terms for the processes of particle loss and income by excitation and deexcitation, ionization and recombination as well as losses due to diffusion and radiation. The challenge of solution of such large system is also discussed.

  16. Risk of Dementia Associated with Elevated Plasma Homocysteine in a Latin American Population

    Directory of Open Access Journals (Sweden)

    Inara J. Chacón

    2009-01-01

    Full Text Available The relationship between total homocysteine (tHcy and dementia risk remains controversial, as the association varies among populations and dementia subtypes. We studied a Venezuelan population that has high prevalence of both elevated tHcy and dementia. We tested the hypotheses that (1 elevated tHcy is associated with increased dementia risk, (2 the risk is greater for vascular dementia (VaD than for Alzheimer's disease (AD, and (3 a history of stroke may partly explain this association. 2100 participants (≥55 years old of the Maracaibo Aging Study underwent standardized neurological, neuropsychiatric, and cardiovascular assessments. Elevated tHcy was significantly associated with dementia, primarily VaD. When history of stroke and other confounding factors were taken into account, elevated tHcy remained a significant risk factor in older (>66 years, but not in younger (55–66 years subjects. Ongoing studies of this population may provide insight into the mechanism by which tHcy increases risk for dementia.

  17. Ice sheet in peril

    DEFF Research Database (Denmark)

    Hvidberg, Christine Schøtt

    2016-01-01

    Earth's large ice sheets in Greenland and Antarctica are major contributors to sea level change. At present, the Greenland Ice Sheet (see the photo) is losing mass in response to climate warming in Greenland (1), but the present changes also include a long-term response to past climate transitions....... On page 590 of this issue, MacGregor et al. (2) estimate the mean rates of snow accumulation and ice flow of the Greenland Ice Sheet over the past 9000 years based on an ice sheet-wide dated radar stratigraphy (3). They show that the present changes of the Greenland Ice Sheet are partly an ongoing...... response to the last deglaciation. The results help to clarify how sensitive the ice sheet is to climate changes....

  18. Ice sheet in peril

    DEFF Research Database (Denmark)

    Hvidberg, Christine Schøtt

    2016-01-01

    Earth's large ice sheets in Greenland and Antarctica are major contributors to sea level change. At present, the Greenland Ice Sheet (see the photo) is losing mass in response to climate warming in Greenland (1), but the present changes also include a long-term response to past climate transitions....... On page 590 of this issue, MacGregor et al. (2) estimate the mean rates of snow accumulation and ice flow of the Greenland Ice Sheet over the past 9000 years based on an ice sheet-wide dated radar stratigraphy (3). They show that the present changes of the Greenland Ice Sheet are partly an ongoing...... response to the last deglaciation. The results help to clarify how sensitive the ice sheet is to climate changes....

  19. Fluctuation dynamics in reconnecting current sheets

    Science.gov (United States)

    von Stechow, Adrian; Grulke, Olaf; Ji, Hantao; Yamada, Masaaki; Klinger, Thomas

    2015-11-01

    During magnetic reconnection, a highly localized current sheet forms at the boundary between opposed magnetic fields. Its steep perpendicular gradients and fast parallel drifts can give rise to a range of instabilities which can contribute to the overall reconnection dynamics. In two complementary laboratory reconnection experiments, MRX (PPPL, Princeton) and VINETA.II (IPP, Greifswald, Germany), magnetic fluctuations are observed within the current sheet. Despite the large differences in geometries (toroidal vs. linear), plasma parameters (high vs. low beta) and magnetic configuration (low vs. high magnetic guide field), similar broadband fluctuation characteristics are observed in both experiments. These are identified as Whistler-like fluctuations in the lower hybrid frequency range that propagate along the current sheet in the electron drift direction. They are intrinsic to the localized current sheet and largely independent of the slower reconnection dynamics. This contribution characterizes these magnetic fluctuations within the wide parameter range accessible by both experiments. Specifically, the fluctuation spectra and wave dispersion are characterized with respect to the magnetic topology and plasma parameters of the reconnecting current sheet.

  20. Local structure of the magnetotail current sheet: 2001 Cluster observations

    Directory of Open Access Journals (Sweden)

    A. Runov

    2006-03-01

    Full Text Available Thirty rapid crossings of the magnetotail current sheet by the Cluster spacecraft during July-October 2001 at a geocentric distance of 19 RE are examined in detail to address the structure of the current sheet. We use four-point magnetic field measurements to estimate electric current density; the current sheet spatial scale is estimated by integration of the translation velocity calculated from the magnetic field temporal and spatial derivatives. The local normal-related coordinate system for each case is defined by the combining Minimum Variance Analysis (MVA and the curlometer technique. Numerical parameters characterizing the plasma sheet conditions for these crossings are provided to facilitate future comparisons with theoretical models. Three types of current sheet distributions are distinguished: center-peaked (type I, bifurcated (type II and asymmetric (type III sheets. Comparison to plasma parameter distributions show that practically all cases display non-Harris-type behavior, i.e. interior current peaks are embedded into a thicker plasma sheet. The asymmetric sheets with an off-equatorial current density peak most likely have a transient nature. The ion contribution to the electric current rarely agrees with the current computed using the curlometer technique, indicating that either the electron contribution to the current is strong and variable, or the current density is spatially or temporally structured.

  1. Radiating Current Sheets in the Solar Chromosphere

    CERN Document Server

    Goodman, Michael L

    2014-01-01

    An MHD model of a Hydrogen plasma with flow, an energy equation, NLTE ionization and radiative cooling, and an Ohm's law with anisotropic electrical conduction and thermoelectric effects is used to self-consistently generate atmospheric layers over a $50$ km height range. A subset of these solutions contain current sheets, and have properties similar to those of the lower and middle chromosphere. The magnetic field profiles are found to be close to Harris sheet profiles, with maximum field strengths $\\sim 25-150$ G. The radiative flux $F_R$ emitted by individual sheets is $\\sim 4.9 \\times 10^5 - 4.5 \\times 10^6$ ergs-cm$^{-2}$-s$^{-1}$, to be compared with the observed chromospheric emission rate of $\\sim 10^7$ ergs-cm$^{-2}$-s$^{-1}$. Essentially all emission is from regions with thicknesses $\\sim 0.5 - 13$ km containing the neutral sheet. About half of $F_R$ comes from sub-regions with thicknesses 10 times smaller. A resolution $\\lesssim 5-130$ m is needed to resolve the properties of the sheets. The sheets...

  2. Energy-dispersed ions in the plasma sheet boundary layer and associated phenomena: Ion heating, electron acceleration, Alfvén waves, broadband waves, perpendicular electric field spikes, and auroral emissions

    Directory of Open Access Journals (Sweden)

    A. Keiling

    2006-10-01

    Full Text Available Recent Cluster studies reported properties of multiple energy-dispersed ion structures in the plasma sheet boundary layer (PSBL that showed substructure with several well separated ion beamlets, covering energies from 3 keV up to 100 keV (Keiling et al., 2004a, b. Here we report observations from two PSBL crossings, which show a number of identified one-to-one correlations between this beamlet substructure and several plasma-field characteristics: (a bimodal ion conics (<1 keV, (b field-aligned electron flow (<1 keV, (c perpendicular electric field spikes (~20 mV/m, (d broadband electrostatic ELF wave packets (<12.5 Hz, and (e enhanced broadband electromagnetic waves (<4 kHz. The one-to-one correlations strongly suggest that these phenomena were energetically driven by the ion beamlets, also noting that the energy flux of the ion beamlets was 1–2 orders of magnitude larger than, for example, the energy flux of the ion outflow. In addition, several more loosely associated correspondences were observed within the extended region containing the beamlets: (f electrostatic waves (BEN (up to 4 kHz, (g traveling and standing ULF Alfvén waves, (h field-aligned currents (FAC, and (i auroral emissions on conjugate magnetic field lines. Possible generation scenarios for these phenomena are discussed. In conclusion, it is argued that the free energy of magnetotail ion beamlets drove a variety of phenomena and that the spatial fine structure of the beamlets dictated the locations of where some of these phenomena occurred. This emphasizes the notion that PSBL ion beams are important for magnetosphere-ionosphere coupling. However, it is also shown that the dissipation of electromagnetic energy flux (at altitudes below Cluster of the simultaneously occurring Alfvén waves and FAC was larger (FAC being the largest than the dissipation of beam kinetic energy flux, and thus these two energy carriers contributed more to the energy transport on PSBL field lines

  3. Association of apolipoprotein E polymorphism with plasma lipids and Alzheimer's disease in a Southern Brazilian population

    Directory of Open Access Journals (Sweden)

    de-Andrade F.M.

    2000-01-01

    Full Text Available Apolipoprotein E (protein: apo E; gene: APOE plays an important role in the multifactorial etiology of both Alzheimer's disease (AD and lipid level concentrations. The polymerase chain reaction (PCR was used to investigate the APOE gene polymorphism in 446 unrelated Caucasians, among them 23 AD patients, and 100 Afro-Brazilians living in Porto Alegre, Brazil. The frequencies of the APOE*2, APOE*3 and APOE*4 alleles were 0.075, 0.810 and 0.115 in Caucasians and 0.075, 0.700 and 0.225 in Afro-Brazilians, respectively (c2 = 8.72, P = 0.013. A highly significant association was observed between the APOE*4 allele and AD in this population-based sample. The APOE*4 frequency in AD patients (39% was about four times higher than in the general Caucasian population (11.5%. The influence of each of the three common APOE alleles on lipid traits was evaluated by the use of the average excess statistic. The E*2 allele is associated with lower levels of triglycerides and of total and non-HDL cholesterol in both men and women. Conversely, the E*4 allele is associated with higher levels of these traits in women only. The effect of APOE alleles was of greater magnitude in women.

  4. Modeling Multiple Plasma Populations During the June 23, 2015 Geomagnetic Storm

    Science.gov (United States)

    Moore, T. E.; DiStefano, N.; Garcia-Sage, K.; Giles, B. L.; Zhang, B.; Pembroke, A. D.

    2016-12-01

    On June 23, 2015 a large geomagnetic storm resulted in the spectacular views of the aurora from places as far southward as West Virginia. The Magnetospheric Multiscale (MMS), which was in its commissioning phase, captured the event on the night-side and dusk-side of Earth in the magnetosphere. Between 3 and 5 UT, MMS data demonstrated periods of ionospheric outflow of low-energy electrons and monoenergetic ions. Notably, during these periods of ionospheric outflow, the pitch angle of the electrons with respect to the magnetic field was predominantly zero degrees, meaning that these particles were mostly moving away from the Earth along open magnetic field lines. In order to test our understanding and ability to accurately model the event, we use the Lyon-Fedder-Mobarry (LFM) model, which is a global magnetohydrodynamic (MHD) model. We show single and multi-fluid simulations of the event in order to demonstrate the effects of ionospheric-origin plasma on the dynamics that MMS observes. Since the addition of ionospheric outflow to the LFM model can only incorporate thermal particles, we created a separate simulation of non-thermal particle trajectories due to Lorentz and gravitational forces based on LFM model data. In this simulation, we find that the outflowing H+, O+, and low-energy electrons observed by MMS come from the pre-midnight auroral region. We also find that the ions and low-energy electrons appear to undergo only minimal acceleration between 2.3 Earth radii and the location of MMS.

  5. Thin current sheets in the deep geomagnetic tail

    Energy Technology Data Exchange (ETDEWEB)

    Pulkkinen, T.I. (Finnish Meteorological Institute, Helsinki (Finland)); Baker, D.N.; Owen, C.J. (NASA/Goddard Space Flight Center, Greenbelt, MD (United States)); Gosling, J.T. (Los Alamos National Lab., NM (United States)); Murphy, N. (Jet Propulsion Lab., Pasadena, CA (United States))

    1993-11-19

    The ISEE-3 magnetic field and plasma electron data from Jan-March 1983 have been searched to study thin current sheets in the deep tail region. 33 events were selected where the spacecraft crossed through the current sheet from lobe to lobe within 15 minutes. The average thickness of the observed current sheets was 2.45R[sub E], and in 24 cases the current sheet was thinner than 3.0R[sub E]; 6 very thin current sheets (thickness [lambda] < 0.5R[sub E]) were found. The electron data show that the very thin current sheets are associated with considerable temperature anisotropy. On average, the electron gradient current was [approximately]17% of the total current, whereas the current arising from the electron temperature anisotropy varied between 8-45% of the total current determined from the lobe field magnitude. 21 refs., 5 figs.

  6. Single-nucleotide polymorphisms in peroxisome proliferator-activated receptor and their association with plasma levels of resistin and the metabolic syndrome in a South Indian population

    Indian Academy of Sciences (India)

    Abdul Haseeb; Mohammad Iliyas; Subhabrata Chakrabarti; Arif A Farooqui; Sudhir R Naik; Sudip Ghosh; Madhuri Suragani; Nasreen Z Ehtesham

    2009-09-01

    Studies on the association of the Pro12Ala and C1431T polymorphisms of PPAR with diabetes and obesity have revealed extensive population-dependent variations. However, association of these polymorphisms with the metabolic syndrome and its individual components has not been well investigated in the Indian population. The Indian population harbours the maximum number of diabetics in the world who are thus more susceptible to metabolic disorders. We screened a South Indian population ( = 699) for a possible association of these polymorphisms with the metabolic syndrome (MS) and type 2 diabetes. We also investigated the correlation of these two single-nucleotide polymorphisms (SNPs) with plasma resistin levels. The C1431T SNP was associated with higher levels of plasma resistin ( = 0.017). Furthermore, C1431T was associated with resistin in different tertiles. Prevalence of the ‘Pro-C’ haplotype decreased with increasing tertiles of resistin (84.1% to 75.4%, = 0.037). Plasma resistin levels were not found to be associated with MS and type 2 diabetes. These results point to a likely association of plasma resistin levels with PPAR polymorphisms in the Indian population.

  7. Atherogenic Index of Plasma Predicts Hyperuricemia in Rural Population: A Cross-Sectional Study from Northeast China

    Directory of Open Access Journals (Sweden)

    Ye Chang

    2016-09-01

    Full Text Available We aimed to determine the association of atherogenic index of plasma (AIP with hyperuricemia (HUA in the rural population of northeast China. This cross-sectional study was conducted in the rural areas of northeast China from January 2012 to August 2013, and the final analysis included data obtained form 5253 men and 6092 women. 1104 participants (9.7% suffered from HUA. Spearman rank test showed that AIP was positively correlated with uric acid in both sexes (r = 0.310 for men and r = 0.347 for women, both p < 0.001. AIP was classified into three groups: the low (<0.11, the intermediate (0.11–0.21 and the increased (>0.21 risk. The prevalence of HUA increased with AIP. Multivariate logistic regression analysis showed that, compared to the low AIP group, participants in increased AIP group had a 2.536-fold risk for HUA (2.164-fold in male and 2.960-fold in female after adjustment for covariates. Results of receiver operating characteristic curves showed that the area under the curve (95% confidence intervals was 0.686 (0.665–0.707 for male and 0.730 (0.706–0.755 for female. We indicated that increased AIP was associated with higher serum uric acid levels and could be identified as an independent risk factor of HUA in the rural population of northeast China.

  8. Thermoforming of foam sheet

    NARCIS (Netherlands)

    Akkerman, Remko; Pronk, Ruud M.

    1997-01-01

    Thermoforming is a widely used process for the manufacture of foam sheet products. Polystyrene foam food trays for instance can be produced by first heating the thermoplastic foam sheet, causing the gas contained to build up pressure and expand, after which a vacuum pressure can be applied to draw t

  9. The Effect of Organic Fertilizers and Flowering Plants on Sheet-Web and Wolf Spider Populations (Araneae: Lycosidae and Linyphiidae) and Its Importance for Pest Control.

    Science.gov (United States)

    El-Nabawy, El-Said M; Tsuda, Katsuo; Sakamaki, Yositaka; Oda, Asahi; Ushijima, Yurie

    2016-01-01

    The main goal of this study was to identify the treatment that increases the populations of spiders, which are effective predators in agroecosystems. In 2013 and 2014 the experimental eggplant (Solanum melongena L.) field was two different treatments, organic fertilizers and chemical fertilizer treatment, and in 2014 we surrounded organic fertilizer plots with the flowering plants mealy cup sage (Salvia farinacea Benth.), spearmint (Mentha spicata L.), and basil (Ocimum basilicum L.). Analysis using repeated measures ANOVA revealed significant influences of fertilizer type on the numbers of linyphiid spiders and Collembola in 2013. In 2014, the numbers of Collembola, thrips, and lycosid and linyphiid spider were higher in organic fertilizer with flowering plants treatment comparing with the chemical fertilizer treatment. Moreover, the numbers of Henosepilachna vigintioctopunctata (F.) were significantly lower in the organic fertilizer with flowering plants treatment than in chemical fertilizers treatment. Finally, we expect that Thysanoptera and Collembola were important alternative prey for linyphiid and lycosid spiders and the use of organic fertilizer and flowering plants enhanced the density of these spiders, and may increase their effectiveness in suppressing the populations of H. vigintioctopunctata (F.).

  10. Mechanics of Sheeting Joints

    Science.gov (United States)

    Martel, S. J.

    2015-12-01

    Physical breakdown of rock across a broad scale spectrum involves fracturing. In many areas large fractures develop near the topographic surface, with sheeting joints being among the most impressive. Sheeting joints share many geometric, textural, and kinematic features with other joints (opening-mode fractures) but differ in that they are (a) discernibly curved, (b) open near the topographic surface, and (c) form subparallel to the topographic surface. Where sheeting joints are geologically young, the surface-parallel compressive stresses are typically several MPa or greater. Sheeting joints are best developed beneath domes, ridges, and saddles; they also are reported, albeit rarely, beneath valleys or bowls. A mechanism that accounts for all these associations has been sought for more than a century: neither erosion of overburden nor high lateral compressive stresses alone suffices. Sheeting joints are not accounted for by Mohr-Coulomb shear failure criteria. Principles of linear elastic fracture mechanics, together with the mechanical effect of a curved topographic surface, do provide a basis for understanding sheeting joint growth and the pattern sheeting joints form. Compressive stresses parallel to a singly or doubly convex topographic surface induce a tensile stress perpendicular to the surface at shallow depths; in some cases this alone could overcome the weight of overburden to open sheeting joints. If regional horizontal compressive stresses, augmented by thermal stresses, are an order of magnitude or so greater than a characteristic vertical stress that scales with topographic amplitude, then topographic stress perturbations can cause sheeting joints to open near the top of a ridge. This topographic effect can be augmented by pressure within sheeting joints arising from water, ice, or salt. Water pressure could be particularly important in helping drive sheeting joints downslope beneath valleys. Once sheeting joints have formed, the rock sheets between

  11. Cell sheet engineering

    Directory of Open Access Journals (Sweden)

    Masayuki Yamato

    2004-05-01

    Full Text Available We have developed ‘cell sheet engineering’ in order to avoid the limitations of tissue reconstruction using biodegradable scaffolds or single cell suspension injection. Our concept is tissue reconstruction, not from single cells, but from cell sheets. Cell sheets are prepared using temperature-responsive culture dishes. Temperature-responsive polymers are covalently grafted onto the dishes, allowing various types of cells to adhere and proliferate at 37°C. The cells spontaneously detach when the temperature is reduced below 32°C without the need for proteolytic enzymes. The confluent cells are noninvasively harvested as single, contiguous cell sheets with intact cell-cell junctions and deposited extracellular matrix (ECM. We have used these harvested cell sheets for various tissue reconstructions, including ocular surfaces, periodontal ligaments, cardiac patches, and bladder augmentation.

  12. Plasma TIMP-1 and CEA in detection of primary colorectal cancer: a prospective, population based study of 4509 high-risk individuals

    DEFF Research Database (Denmark)

    Nielsen, Hans J; Brünner, Nils; Olsen, Jesper;

    2011-01-01

    Objective. The combination of plasma tissue inhibitor of metalloproteinases-1 (TIMP-1) and carcinoembryonic antigen (CEA) may be valuable biomarkers for early detection of colorectal cancer (CRC). A prospective, population based study was performed to validate this hypothesis. Material and method...

  13. Comparison of plasma levels of nutrient-related biomarkers among Japanese populations in Tokyo, Japan, São Paulo, Brazil, and Hawaii, USA.

    Science.gov (United States)

    Iwasaki, Motoki; Franke, Adrian A; Hamada, Gerson S; Miyajima, Nelson T; Sharma, Sangita; Ishihara, Junko; Takachi, Ribeka; Tsugane, Shoichiro; Le Marchand, Loïc

    2015-03-01

    Previous studies of Japanese migrants have suggested that the increase in colorectal cancer rates occurring after migration is slower among Japanese Brazilians than among Japanese Americans. We hypothesized that this difference may partly reflect differences in vegetable and fruit intake between the populations. Using data from validation studies of food frequency questionnaires being used in comparative case-control studies of colorectal adenoma in Tokyo, São Paulo, and Hawaii, plasma carotenoid, retinol, tocopherol, and coenzyme Q10 levels were measured by high-performance liquid chromatography, and 25-hydroxy vitamin D levels were estimated by enzyme-linked immunosorbent assay. Plasma levels were compared by analysis of covariance between 142 Japanese in Tokyo, 79 Japanese Brazilians in São Paulo, and 78 Japanese Americans in Hawaii. Overall, we found significantly lower plasma carotenoid levels, except for lycopene levels, and retinol levels in Japanese Americans compared with Japanese in Tokyo and Japanese Brazilians. The plasma total carotenoid level was highest in Japanese Brazilians. Compared with the mean level among Japanese Brazilians (1741.2 ng/ml), P for difference was 0.03 among Japanese in Tokyo (1514.4 ng/ml) and less than 0.01 for Japanese Americans (1257.7 ng/ml). Plasma lycopene and tocopherol levels did not substantially differ between the three populations. We also found significantly lower plasma levels of 25-hydroxy vitamin D and total coenzyme Q10 in Japanese in Tokyo than in Japanese Americans and Japanese Brazilians. Higher levels of plasma carotenoids among Japanese Brazilians than among Japanese in Tokyo and Hawaii may have contributed to the slower pace of the increase in colorectal cancer rates observed in that population after migration.

  14. Effect of vitamin E intake from food and supplement sources on plasma α- and γ-tocopherol concentrations in a healthy Irish adult population.

    Science.gov (United States)

    Zhao, Yang; Monahan, Frank J; McNulty, Breige A; Gibney, Mike J; Gibney, Eileen R

    2014-11-14

    Vitamin E is believed to play a preventive role in diseases associated with oxidative stress. The aims of the present study were to quantify vitamin E intake levels and plasma concentrations and to assess dietary vitamin E adequacy in Irish adults. Intake data from the National Adult Nutrition Survey were used; plasma samples were obtained from a representative cohort of survey participants. Plasma α- and γ-tocopherol concentrations were measured by HPLC. The main sources of vitamin E in the diet were 'butter, spreadable fats and oils' and 'vegetables and vegetable dishes'. When vitamin E intake from supplements was taken into account, supplements were found to be the main contributor, making a contribution of 29·2 % to vitamin E intake in the total population. Supplement consumers had significantly higher plasma α-tocopherol concentrations and lower plasma γ-tocopherol concentrations when compared with non-consumers. Consumers of 'vitamin E' supplements had significantly higher vitamin E intake levels and plasma α-tocopherol concentrations compared with consumers of other types of supplements, such as multivitamin and fish oil. Comparison with the Institute of Medicine Estimated Average Requirement of 12 mg/d indicated that when vitamin E intake from food and supplement sources was taken into account, 100 % of the study participants achieved the recommended intake levels. When vitamin E intake from food sources was taken into account, only 68·4 % of the females were found to achieve the recommended intake levels compared with 99·2 % of the males. The results of the present study show that dietary vitamin E intake has a significant effect on plasma α- and γ-tocopherol concentrations. Furthermore, they show that the consumption of supplements is a major contributor to overall intake and has a significant effect on plasma vitamin E concentrations in the Irish population.

  15. Criticality and turbulence in a resistive magnetohydrodynamic current sheet.

    Science.gov (United States)

    Klimas, Alexander J; Uritsky, Vadim M

    2017-02-01

    Scaling properties of a two-dimensional (2d) plasma physical current-sheet simulation model involving a full set of magnetohydrodynamic (MHD) equations with current-dependent resistivity are investigated. The current sheet supports a spatial magnetic field reversal that is forced through loading of magnetic flux containing plasma at boundaries of the simulation domain. A balance is reached between loading and annihilation of the magnetic flux through reconnection at the current sheet; the transport of magnetic flux from boundaries to current sheet is realized in the form of spatiotemporal avalanches exhibiting power-law statistics of lifetimes and sizes. We identify this dynamics as self-organized criticality (SOC) by verifying an extended set of scaling laws related to both global and local properties of the current sheet (critical susceptibility, finite-size scaling of probability distributions, geometric exponents). The critical exponents obtained from this analysis suggest that the model operates in a slowly driven SOC state similar to the mean-field state of the directed stochastic sandpile model. We also investigate multiscale correlations in the velocity field and find them numerically indistinguishable from certain intermittent turbulence (IT) theories. The results provide clues on physical conditions for SOC behavior in a broad class of plasma systems with propagating instabilities, and suggest that SOC and IT may coexist in driven current sheets which occur ubiquitously in astrophysical and space plasmas.

  16. Criticality and turbulence in a resistive magnetohydrodynamic current sheet

    Science.gov (United States)

    Klimas, Alexander J.; Uritsky, Vadim M.

    2017-02-01

    Scaling properties of a two-dimensional (2d) plasma physical current-sheet simulation model involving a full set of magnetohydrodynamic (MHD) equations with current-dependent resistivity are investigated. The current sheet supports a spatial magnetic field reversal that is forced through loading of magnetic flux containing plasma at boundaries of the simulation domain. A balance is reached between loading and annihilation of the magnetic flux through reconnection at the current sheet; the transport of magnetic flux from boundaries to current sheet is realized in the form of spatiotemporal avalanches exhibiting power-law statistics of lifetimes and sizes. We identify this dynamics as self-organized criticality (SOC) by verifying an extended set of scaling laws related to both global and local properties of the current sheet (critical susceptibility, finite-size scaling of probability distributions, geometric exponents). The critical exponents obtained from this analysis suggest that the model operates in a slowly driven SOC state similar to the mean-field state of the directed stochastic sandpile model. We also investigate multiscale correlations in the velocity field and find them numerically indistinguishable from certain intermittent turbulence (IT) theories. The results provide clues on physical conditions for SOC behavior in a broad class of plasma systems with propagating instabilities, and suggest that SOC and IT may coexist in driven current sheets which occur ubiquitously in astrophysical and space plasmas.

  17. Algebra task & drill sheets

    CERN Document Server

    Reed, Nat

    2011-01-01

    For grades 6-8, our State Standards-based combined resource meets the algebraic concepts addressed by the NCTM standards and encourages the students to review the concepts in unique ways. The task sheets introduce the mathematical concepts to the students around a central problem taken from real-life experiences, while the drill sheets provide warm-up and timed practice questions for the students to strengthen their procedural proficiency skills. Included are opportunities for problem-solving, patterning, algebraic graphing, equations and determining averages. The combined task & drill sheets

  18. Algebra task & drill sheets

    CERN Document Server

    Reed, Nat

    2011-01-01

    For grades 3-5, our State Standards-based combined resource meets the algebraic concepts addressed by the NCTM standards and encourages the students to review the concepts in unique ways. The task sheets introduce the mathematical concepts to the students around a central problem taken from real-life experiences, while the drill sheets provide warm-up and timed practice questions for the students to strengthen their procedural proficiency skills. Included are opportunities for problem-solving, patterning, algebraic graphing, equations and determining averages. The combined task & drill sheets

  19. Excitation of plasma waves by unstable photoelectron and thermal electron populations on closed magnetic field lines in the Martian ionosphere

    Directory of Open Access Journals (Sweden)

    N. Borisov

    2005-06-01

    Full Text Available It is argued that anisotropic electron pitch angle distributions in the closed magnetic field regions of the Martian ionosphere gives rise to excitation of plasma instabilities. We discuss two types of instabilities that are excited by two different populations of electrons. First, the generation of Langmuir waves by photoelectrons with energies of the order of 10eV is investigated. It is predicted that the measured anisotropy of their pitch angle distribution at the heights z≈400km causes excitation of waves with frequencies f~30kHz and wavelengths λ~30m. Near the terminators the instability of the electrostatic waves with frequencies of the order of or less than the electron gyrofrequency exited by thermal electrons is predicted. The typical frequencies of these waves depend on the local magnitude of the magnetic field and can achieve values f~3-5kHz above strong crustal magnetic fields.

  20. Interactions between ice sheets, climate and the solid Earth

    NARCIS (Netherlands)

    Berg, J. van den

    2007-01-01

    The melting of ice sheets in response to increasing temperatures is an important contribution to present day sea level rise. To predict the amount of sea level rise and to assess its impact on populated coastal regions, an increased understanding of the physical processes governing ice sheets is ess

  1. HRSA Data Fact Sheets

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Health Resources and Services Administration (HRSA) Data Fact Sheets provide summary data about HRSA’s activities in each Congressional District, County, State,...

  2. Pharmacogenomics Fact Sheet

    Science.gov (United States)

    ... incorporate genomic results into medical care. Other NIGMS Fact Sheets Related Links Up to top This page last reviewed on September 28, 2017 Social Media Links Bookmark & Share Free Subscriptions Twitter Facebook ...

  3. Respirator Fact Sheet

    Science.gov (United States)

    ... have expiration dates that should be checked before purchase. Also, over time your mask can get old ... Respirator Fact Sheet [PDF - 706 KB] Follow NIOSH Facebook Flickr Pinterest Twitter YouTube NIOSH Homepage NIOSH A- ...

  4. Energy information sheets

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-07-01

    The National Energy Information Center (NEIC), as part of its mission, provides energy information and referral assistance to Federal, State, and local governments, the academic community, business and industrial organizations, and the public. The Energy Information Sheets was developed to provide general information on various aspects of fuel production, prices, consumption, and capability. Additional information on related subject matter can be found in other Energy Information Administration (EIA) publications as referenced at the end of each sheet.

  5. 2013 social balance sheet

    OpenAIRE

    Pierrette Heuse

    2014-01-01

    The transposition into national law of Directive 2013/34/EU on the annual financial statements of companies, expected by no later than July 2015, could alter the statistical obligations on small firms in connection with the filing of their annual accounts. In any case, the social balance sheet can no longer form an integral part of their accounts. Nevertheless, it contains original information whose usefulness is highlighted, on the basis of the social balance sheets for 2012, by examining th...

  6. Prevalence of the angiotensin I converting enzyme insertion/deletion polymorphism, plasma angiotensin converting enzyme activity, and left ventricular mass in a normotensive Chilean population.

    Science.gov (United States)

    Jalil, J E; Piddo, A M; Cordova, S; Chamorro, G; Braun, S; Jalil, R; Vega, J; Jadue'P, L; Lavandero, S; Lastra, P

    1999-07-01

    The aim of this study was to estimate the prevalence of the different alleles of the angiotensin converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism and associated plasma ACE activity, as well as cardiac echocardiographic structure, in a healthy Chilean population. We selected 117 healthy normotensive subjects (aged 45 to 60 years, middle socioeconomic status, nonobese, and nondiabetic) from a population-based study concerning the prevalence of risk factors for chronic diseases (Conjunto de Acciones Para la Reducción Multifactorial de las Enfermedades no Transmisibles [CARMEN]). The frequencies of the I and D alleles were 0.57 and 0.43, respectively. Mean plasma ACE activity was 15.3 +/- 3.9 U/mL. Compared with subjects with the II genotype, plasma ACE activity was significantly higher in subjects with the ID and DD genotypes with no difference between them. No correlation was observed between blood pressure and plasma ACE activity. Among the three different genotypes there was no difference in left ventricular (LV) dimensions or in LV mass. No correlation between plasma ACE activity and LV mass was observed for either gender or different genotypes. Multivariate linear regression analysis using LV mass and LV mass index as dependent variables showed independent effects (P < .05) for gender (higher LV mass in men) and diastolic blood pressure, but not for the DD genotype. In conclusion, in this population, the presence of the D allele on the ACE gene determined higher circulating ACE activity. However, in this normotensive healthy population, male gender and diastolic blood pressure, but not the presence of the D allele, were associated with increased LV mass.

  7. Performance of Fasting Plasma Glucose and Postprandial Urine Glucose in Screening for Diabetes in Chinese High-risk Population

    Institute of Scientific and Technical Information of China (English)

    Bing-Quan Yang; Yang Lu; Jia-Jia He; Tong-Zhi Wu; Zuo-Ling Xie; Cheng-Hao Lei; Yi Zhou

    2015-01-01

    Background: The conventional approaches to diabetes screening are potentially limited by poor compliance and laboratory demand.This study aimed to evaluate the performance of fasting plasma glucose (FPG) and postprandial urine glucose (PUG) in screening for diabetes in Chinese high-risk population.Methods: Nine hundred and nine subjects with high-risk factors of diabetes underwent oral glucose tolerance test after an overnight fast.FPG, hemoglobin A 1 c, 2-h plasma glucose (2 h-PG), and 2 h-PUG were evaluated.Diabetes and prediabetes were defined by the American Diabetes Association criteria.The area under the receiver operating characteristic (ROC) curve was used to evaluate the diagnostic accuracy of 2 h-PUG, and the optimal cut-offdetermined to provide the largest Youden index.Spearman correlation was used for relationship analysis.Results: Among 909 subjects, 33.4% (304/909) of subjects had prediabetes, and 17.2% (156/909) had diabetes.The 2 h-PUG was positively related to FPG and 2 h-PG (r =0.428 and 0.551, respectively, both P < 0.001).For estimation of 2 h-PG ≥ 7.8 mmol/L and 2 h-PG ≥ 1 1.1 mmol/L using 2 h-PUG, the area under the ROC curve were 0.772 (95% confidence interval [CI]: 0.738-0.806) and 0.885 (95% CI:0.850~.921), respectively.The corresponding optimal cut-offs for 2 h-PUG were 5.6 mmol/L and 7.5 mmol/L, respectively.Compared with FPG alone, FPG combined with 2 h-PUG had a higher sensitivity for detecting glucose abnormalities (84.1% vs.73.7%, P < 0.001) and diabetes (82.7% vs.48.1%, P < 0.001).Conclusion: FPG combined with 2 h-PUG substantially improves the sensitivity in detecting prediabetes and diabetes relative to FPG alone, and may represent an efficient layperson-oriented diabetes screening method.

  8. Reactive Atom Plasma Processing of Slumped Glass Wedges Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The Reactive Atom Plasma (RAPTM) process will be evaluated as a rapid and practical method for fabricating precision wedges in glass sheets. The glass sheets are to...

  9. Current sheets at three-dimensional magnetic nulls: Effect of compressibility

    CERN Document Server

    Pontin, D I; Galsgaard, K

    2007-01-01

    The nature of current sheet formation in the vicinity of three-dimensional magnetic null points is investigated. The particular focus is upon the effect of the compressibility of the plasma on the qualitative and quantitative properties of the current sheet. It is found that as the incompressible limit is approached, the collapse of the null point is suppressed, and instead an approximately planar current sheet aligned to the fan plane is present. Both the peak current and peak reconnection rate are reduced. The results imply that previous analytical solutions for steady-state reconnection at fan current sheets are dynamically accessible, while spine current sheet solutions are not.

  10. Safety advice sheets

    CERN Multimedia

    HSE Unit

    2013-01-01

    You never know when you might be faced with questions such as: when/how should I dispose of a gas canister? Where can I find an inspection report? How should I handle/store/dispose of a chemical substance…?   The SI section of the DGS/SEE Group is primarily responsible for safety inspections, evaluating the safety conditions of equipment items, premises and facilities. On top of this core task, it also regularly issues “Safety Advice Sheets” on various topics, designed to be of assistance to users but also to recall and reinforce safety rules and procedures. These clear and concise sheets, complete with illustrations, are easy to display in the appropriate areas. The following safety advice sheets have been issued so far: Other sheets will be published shortly. Suggestions are welcome and should be sent to the SI section of the DGS/SEE Group. Please send enquiries to general-safety-visits.service@cern.ch.

  11. Energy information sheets

    Energy Technology Data Exchange (ETDEWEB)

    1993-12-02

    The National Energy Information Center (NEIC), as part of its mission, provides energy information and referral assistance to Federal, State, and local governments, the academic community, business and industrial organizations, and the general public. Written for the general public, the EIA publication Energy Information Sheets was developed to provide information on various aspects of fuel production, prices, consumption and capability. The information contained herein pertains to energy data as of December 1991. Additional information on related subject matter can be found in other EIA publications as referenced at the end of each sheet.

  12. Ice Sheets & Ice Cores

    DEFF Research Database (Denmark)

    Mikkelsen, Troels Bøgeholm

    Since the discovery of the Ice Ages it has been evident that Earth’s climate is liable to undergo dramatic changes. The previous climatic period known as the Last Glacial saw large oscillations in the extent of ice sheets covering the Northern hemisphere. Understanding these oscillations known...... as Dansgaard-Oeschger (DO) events would add to our knowledge of the climatic system and – hopefully – enable better forecasts. Likewise, to forecast possible future sea level rise it is crucial to correctly model the large ice sheets on Greenland and Antarctica. This project is divided into two parts...

  13. Examination on the Macroeconomic Implication of Population Structure: From the Perspective of Balance Sheet%从资产负债表角度考察人口结构的宏观含义

    Institute of Scientific and Technical Information of China (English)

    徐盛发; 巴曙松

    2011-01-01

    中国“人口红利”趋于弱化的主要影响是低利率格局将逐步发生改变,从而提高负债方融资的整体成本,这反过来将对资产方投资配置产生冲击。为此,本文从国家资产负债表的角度考察人口结构变迁的宏观含义,人口红利趋于消失意味着融资杠杆能力的弱化以及投资效率的降低,这将导致一个经济体合适的、可持续的潜在增长率逐步呈现下行态势。人口结构对国家资产负债表的冲击也限制了政策的腾挪空间,经济增长中枢速度的平稳回落以及通货膨胀中枢水平的上升,意味着决策者如果以低物价和高增长组合作为政策目标,将可能导致紧缩过度或刺激过度。%China' s "demographic dividend" leads to high saving rates, low interest rates and high investment rates on macroeconomic level. With the "demographic dividend" to the "population balance" changes, low interest rates will gradually change undoubtedly. Then the overall cost of financing in liability side will be increased, which has an impact on the investment allocation in asset side. From the balance sheet perspective of the whole country, we can expect the financial constrains will be strengthened and the efficiency of investment will be reduced as the disappearance of "demographic dividend". The above three effects result in a slow downward trend of potential economic growth rate. In addition, from the economic cycle perspective, the change in population structure limits the operation space of policy, decreases the economic growth rates, and increases the inflation. That means either excessive economic contraction, or excessive stimulation will happen if the decision - maker has low prices and high growth portfolio as a policy goal.

  14. Relation between current sheets and vortex sheets in stationary incompressible MHD

    Directory of Open Access Journals (Sweden)

    D. H. Nickeler

    2012-03-01

    Full Text Available Magnetohydrodynamic configurations with strong localized current concentrations and vortices play an important role in the dissipation of energy in space and astrophysical plasma. Within this work we investigate the relation between current sheets and vortex sheets in incompressible, stationary equilibria. For this approach it is helpful that the similar mathematical structure of magnetohydrostatics and stationary incompressible hydrodynamics allows us to transform static equilibria into stationary ones. The main control function for such a transformation is the profile of the Alfvén-Mach number MA, which is always constant along magnetic field lines, but can change from one field line to another. In the case of a global constant MA, vortices and electric current concentrations are parallel. More interesting is the nonlinear case, where MA varies perpendicular to the field lines. This is a typical situation at boundary layers like the magnetopause, heliopause, the solar wind flowing around helmet streamers and at the boundary of solar coronal holes. The corresponding current and vortex sheets show in some cases also an alignment, but not in every case. For special density distributions in 2-D, it is possible to have current but no vortex sheets. In 2-D, vortex sheets of field aligned-flows can also exist without strong current sheets, taking the limit of small Alfvén Mach numbers into account. The current sheet can vanish if the Alfvén Mach number is (almost constant and the density gradient is large across some boundary layer. It should be emphasized that the used theory is not only valid for small Alfvén Mach numbers MA << 1, but also for MA ≲ 1. Connection to other theoretical approaches and observations and physical effects in space plasmas are presented. Differences in the various aspects of theoretical investigations of current sheets and vortex

  15. Non-oriented electrical sheets

    Science.gov (United States)

    Brissonneau, Pierre

    1984-02-01

    After placing the economic and technological importance of non-oriented magnetic sheets on the same level as that of grain-oriented sheets, the recent stages in the history of non-oriented sheets are recalled. The progress made in the knowledge of the physics of magnetism now allows the functions of the principal properties of non-oriented sheets to be analyzed. Current production of non-oriented sheets is marked by an evolution towards a split of the market between top-grade sheets, which could still be improved significantly, and lower grades, for which the cost of production continues to be practically the only determining factor.

  16. Dynamics of 103K/N and 184M/V HIV-1 drug resistant populations: relative comparison in plasma virus RNA versus CD45RO+T cell proviral DNA

    DEFF Research Database (Denmark)

    Jakobsen, Martin Roelsgaard; Tolstrup, M; Bertelsen, L

    2007-01-01

    BACKGROUND: Viral populations defined by 103K/N and 184M/V as linked or single mutations in the HIV-1 reverse transcriptase gene were investigated in plasma samples and compared with previous findings in the CD45RO(+)T cell compartment. OBJECTIVE: To develop an ARMS assay for plasma virions and t...... an unequal distribution of linked-mutation populations in plasma and CD45RO(+)T cells. Furthermore, the linked 103N-184V mutation may be more fit than the single 184V mutation and this linked population emerges rapidly under inadequate drug pressure. Udgivelsesdato: 2007-Jul...

  17. Plasma Matrix Metalloproteinase-9 Levels Predict First-Time Coronary Heart Disease: An 8-Year Follow-Up of a Community-Based Middle Aged Population.

    Directory of Open Access Journals (Sweden)

    Peter Garvin

    Full Text Available The enzyme in matrix metalloproteinase (MMP-9 has been suggested to be an important determinant of plaque degradation. While several studies have shown elevated levels in patients with coronary heart disease, results in prospective population based studies evaluating MMP-9 in relation to first time coronary events have been inconclusive. As of today, there are four published studies which have measured MMP-9 in serum and none using plasma. Measures of MMP-9 in serum have been suggested to have more flaws than measures in plasma.To investigate the independent association between plasma levels of MMP-9 and first-time incidence of coronary events in an 8-year follow-up.428 men and 438 women, aged 45-69 years, free of previous coronary events and stroke at baseline, were followed-up. Adjustments were made for sex, age, socioeconomic position, behavioral and cardiovascular risk factors, chronic disease at baseline, depressive symptoms, interleukin-6 and C-reactive protein.53 events were identified during a risk-time of 6 607 person years. Hazard ratio (HR for MMP-9 after adjustment for all covariates were HR = 1.44 (1.03 to 2.02, p = 0.033. Overall, the effect of adjustments for other cardiovascular risk factors was low.Levels of plasma MMP-9 are independently associated with risk of first-time CHD events, regardless of adjustments. These results are in contrast to previous prospective population-based studies based on MMP-9 in serum. It is essential that more studies look at MMP-9 levels in plasma to further evaluate the association with first coronary events.

  18. Randomised controlled trial of the effect of long-term selenium supplementation on plasma cholesterol in an elderly Danish population

    DEFF Research Database (Denmark)

    Cold, Frederik; Winther, Kristian H; Pastor-Barriuso, Roberto

    2015-01-01

    Although cross-sectional studies have shown a positive association between Se and cholesterol concentrations, a recent randomised controlled trial in 501 elderly UK individuals of relatively low-Se status found that Se supplementation for 6 months lowered total plasma cholesterol. The Danish......) or 300 (n 119) μg Se-enriched yeast or matching placebo-yeast tablets (n 126) daily for 5 years. A total of 468 participants continued the study for 6 months and 361 participants, equally distributed across treatment groups, continued for 5 years. Plasma samples were analysed for total and HDL......-cholesterol and for total Se concentrations at baseline, 6 months and 5 years. The effect of different doses of Se supplementation on plasma lipid and Se concentrations was estimated by using linear mixed models. Plasma Se concentration increased significantly and dose-dependently in the intervention groups after 6 months...

  19. A study on relative populations and gain coefficients of neon-like krypton for fast moving plasma in capillary discharges

    Energy Technology Data Exchange (ETDEWEB)

    Masnavi, M.; Kikuchi, T.; Nakajima, M.; Horioka, K. [Tokyo Inst. of Technology, Dept. of Energy Sciences, Yokohama, Kanagawa (Japan)

    2002-06-01

    X-ray laser gains and the level populations for collisionally pumped neon (Ne)-like Krypton (KrXXVII) ions have been studied considering the 27 - levels of the 2s{sup 2}2p{sup 6}, 2s{sup 2}2p{sup 5}3s, 2s{sup 2}2p{sup 5}3p and 2s{sup 2}2p{sup 5}3d configurations. It was found that large gains on the 3p {sup 1}S{sub 0} {yields} 3s {sup 3}P{sub 1}, 3p {sup 3}D{sub 2} {yields} 3s {sup 3}P{sub 1}, and 3p {sup 3}S{sub 1} {yields} 3s {sup 1}P{sub 1} transitions are formed for the electron density between 10{sup 20} and 10{sup 22} cm{sup -3} at the electron temperatures 0.9,1 and 3 keV. The effect of the opacity of the 3d{sup 1}P{sub 1} - 2p{sup 61}S{sub 0}, 3d{sup 3}D{sub 1} - 2p{sup 61}S{sub 0}, 3d{sup 3}P{sub 1} - 2p{sup 61}S{sub 0}, 3s{sup 3}P{sub 1} - 2p{sup 61}S{sub 0} and 3s{sup 1}P{sub 1} - 2p{sup 61}S{sub 0} transitions are performed using the escape probability factor approximation, for both the static and dynamic plasmas, which include the effect of the large velocity gradient. In addition, we found some theoretical line-intensity ratios that are sensitive on the electron density, the electron temperature, and also opacity in the interest regime of Ne-like Krypton x-ray laser. (author)

  20. Evaluation of the Association of Plasma Pentraxin 3 Levels with Type 2 Diabetes and Diabetic Nephropathy in a Malay Population

    Directory of Open Access Journals (Sweden)

    Norhashimah Abu Seman

    2013-01-01

    Full Text Available Recent reports have demonstrated that elevated plasma long pentraxin 3 (PTX3 levels are associated with cardiovascular and chronic kidney diseases. In the current study, we investigated the plasma PTX3 levels in 296 Malay subjects including the subjects with normal glucose tolerance (NGT and type 2 diabetes (T2DM patients with or without DN by using an enzyme-linked immune-sorbent assay. Results showed that in males, plasma PTX3 levels in T2DM patients without DN were lower than that in the subjects with NGT (2.78 versus 3.98 ng/mL; P=0.021. Plasma PTX3 levels in T2DM patients with DN were decreased compared to the patients without DN (1.63 versus 2.78 ng/mL; P=0.013. In females, however, no significant alteration of plasma PTX3 levels among NGT subjects and T2DM patients with and without DN was detected. Furthermore, an inverse correlation between PTX3 and body mass index was found in male subjects with NGT (P=0.012; r=-0.390, but not in male T2DM patients, neither in all females. The current study provided the first evidence that decreased plasma PTX3 levels are associated with T2DM and DN in Malay men and also suggested that PTX3 may have different effects in DN and chronic kidney diseases.

  1. Production (information sheets)

    NARCIS (Netherlands)

    2007-01-01

    Documentation sheets: Geo energy 2 Integrated System Approach Petroleum Production (ISAPP) The value of smartness 4 Reservoir permeability estimation from production data 6 Coupled modeling for reservoir application 8 Toward an integrated near-wellbore model 10 TNO conceptual framework for "E&P Unce

  2. Burns Fact Sheet

    Science.gov (United States)

    ... and Answers page . Share Print E-mail House Image Highlight Header Learn More Highlight Body Other NIGMS Fact Sheets Related Links Up to top This page last reviewed on April 06, 2016 Social Media Links Bookmark & Share Free Subscriptions Twitter Facebook YouTube ...

  3. Ethanol Basics (Fact Sheet)

    Energy Technology Data Exchange (ETDEWEB)

    2015-01-01

    Ethanol is a widely-used, domestically-produced renewable fuel made from corn and other plant materials. More than 96% of gasoline sold in the United States contains ethanol. Learn more about this alternative fuel in the Ethanol Basics Fact Sheet, produced by the U.S. Department of Energy's Clean Cities program.

  4. SILICON CARBIDE DATA SHEETS

    Science.gov (United States)

    These data sheets present a compilation of a wide range of electrical, optical and energy values for alpha and beta- silicon carbide in bulk and film...spectrum. Energy data include energy bands, energy gap and energy levels for variously-doped silicon carbide , as well as effective mass tables, work

  5. Pseudomonas - Fact Sheet

    OpenAIRE

    Public Health Agency

    2012-01-01

    Fact sheet on Pseudomonas, including:What is Pseudomonas?What infections does it cause?Who is susceptible to pseudomonas infection?How will I know if I have pseudomonas infection?How can Pseudomonas be prevented from spreading?How can I protect myself from Pseudomonas?How is Pseudomonas infection treated?

  6. Residual stress in plasma sprayed ceramic turbine tip and gas path seal specimens

    Science.gov (United States)

    Hendricks, R. C.; Mcdonald, G.; Mullen, R. L.

    1983-01-01

    The residual stresses in a ceramic sheet material used for turbine blade tip gas path seals, were estimated. These stresses result from the plasma spraying process which leaves the surface of the sheet in tension. To determine the properties of plasma sprayed ZrO2-Y2O3 sheet material, its load deflection characteristics were measured. Estimates of the mechanical properties for sheet materials were found to differ from those reported for plasma sprayed bulk materials.

  7. Association Between Intercellular Adhesion Molecule-1, -2, -3 Plasma Levels and Disease Activity of Ankylosing Spondylitis in the Chinese Han Population.

    Science.gov (United States)

    Liu, Ruyin; Yue, Zongjin; Peng, Xiaoyan; Wang, Xinli; Feng, Zhongkai; Wan, Long

    2016-05-01

    We investigated the association between ICAM-1, -2, -3 plasma levels and ankylosing spondylitis (AS) disease activity. In the present study, we aimed to investigate the association between ICAM-1, -2, -3 plasma levels and AS disease activity in the Chinese Han population. AS is a chronic inflammatory rheumatic disease that effects the sacroiliac joints and axial skeleton. The intercellular adhesion molecules (ICAMs) are members of the immunoglobulin superfamily and have been identified to play major roles in inflammation and immune responses. A total of 60 patients with AS and 60 healthy individuals were selected. The plasma levels of proinflammatory cytokines, including tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), and ICAM-1, -2, -3, were analyzed by ELISA. Disease severity-related indexes, including the Bath ankylosing spondylitis disease activity index (BASDAI), Bath ankylosing spondylitis functional index (BASFI), and ankylosing spondylitis disease activity score (ASDAS), were assessed, along with the erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) level. Both ICAM-1 and ICAM-2 levels in plasma were markedly increased in AS patients compared with levels in the plasma of controls. There was no difference between controls and patients in term of ICAM-3 levels. Furthermore, in patients, correlation analysis showed that TNF-α and IL-6 production, as well as the ESR and CRP levels, have positive relationships with ICAM-1 and ICAM-2 plasma levels; the BASDAI, BASFI, and ASDAS scores were also found to be positively correlated with ICAM-2. However, no significant correlations between ICAM-1 levels and BASDAI, BASFI, or ASDAS were detected in our study. The current findings suggest that ICAM-2 may be a potential biomarker reflecting disease activity and functional ability in AS patients. 5.

  8. Numerical analysis of the current sheet near a magnetic null line

    Energy Technology Data Exchange (ETDEWEB)

    Brushlinskii, K.V.; Zaborov, A.M.; Syrovatskii, S.I.

    1980-03-01

    A mathematical model is constructed for the two-dimensional MHD plasma flow near a magnetic null line in a perturbing electric field. A numerical study is also carried out. This type of flow is the key element of the reconnection of magnetic lines of force and is being studied in connection with the mechanism for solar flares, the magnetospheres of planes, and certain questions in thermonuclear fusion. The results show that during this flow a nearly steady-state current sheet forms with a characteristic two-dimensional configuration. The sheet has four outgrowths corresponding to slow MHD shock waves. The geometric shape of the sheet and the maximum current in it are determined primarily by the plasma conductivity. The dependence of the sheet properties on the gas pressure is very weak. The thermal conditions in the flow, which are related to the heat conduction and radiation, strongly affect the plasma density distribution on the current sheet.

  9. Current sheets at three-dimensional magnetic nulls: Effect of compressibility

    Science.gov (United States)

    Pontin, D. I.; Bhattacharjee, A.; Galsgaard, K.

    2007-05-01

    The nature of current sheet formation in the vicinity of three-dimensional (3D) magnetic null points is investigated. The particular focus is upon the effect of the compressibility of the plasma on the qualitative and quantitative properties of the current sheet. An initially potential 3D null is subjected to shearing perturbations, as in a previous paper [Pontin et al., Phys. Plasmas 14, 052106 (2007)]. It is found that as the incompressible limit is approached, the collapse of the null point is suppressed and an approximately planar current sheet aligned to the fan plane is present instead. This is the case regardless of whether the spine or fan of the null is sheared. Both the peak current and peak reconnection rate are reduced. The results have a bearing on previous analytical solutions for steady-state reconnection in incompressible plasmas, implying that fan current sheet solutions are dynamically accessible, while spine current sheet solutions are not.

  10. Fast Light-Sheet Scanner

    Science.gov (United States)

    Hunter, William W., Jr.; Humphreys, William M., Jr.; Bartram, Scott M.

    1995-01-01

    Optomechanical apparatus maintains sheet of pulsed laser light perpendicular to reference axis while causing sheet of light to translate in oscillatory fashion along reference axis. Produces illumination for laser velocimeter in which submicrometer particles entrained in flow illuminated and imaged in parallel planes displaced from each other in rapid succession. Selected frequency of oscillation range upward from tens of hertz. Rotating window continuously shifts sheet of light laterally while maintaining sheet parallel to same plane.

  11. Fetal rhd genotyping from maternal plasma in a population with a highly diverse ethnic background Genotipagem rhd fetal por meio do plasma materno em uma população de alta diversidade étnica

    Directory of Open Access Journals (Sweden)

    Isabela Nelly Machado

    2006-08-01

    Full Text Available OBJECTIVE: To establish the performance of conventional PCR as a noninvasive method for fetal genotyping, by free fetal DNA analysis of distinct RHD regions from maternal plasma, in a population of a diverse ethnic origin. METHODS: We conducted a validity of the diagnostic test by analyzing 81 plasma samples from RhD-negative Brazilian pregnant women, from 4 to 41 gestational weeks. We tested for exon 10 and intron 4 gene regions by allele specific-PCR. Fetal RHD genotyping by PCR on maternal plasma was compared to serologic RhD typing in the neonatal period. RESULTS: Samples were obtained as follows: 15 in the 1st, 37 in the 2nd and 29 in the 3rd trimester. General accuracy was 97.3%, sensitivity of 98.3% and specificity of 93.8%. CONCLUSIONS: Conventional PCR is an accurate method for fetal RHD genotyping on maternal plasma, even in a population of mixed ethnic origin.OBJETIVO: Avaliar o desempenho da reação em cadeia da polimerase (PCR em gel (convencional como método diagnóstico não-invasivo para a genotipagem RHD fetal, por meio da análise do plasma materno. MÉTODOS: Foi conduzido um estudo de validação de teste diagnóstico a partir de 81 amostras sangüíneas obtidas de gestantes brasileiras RhD-negativo, entre 4 e 41 semanas de gestação. As regiões exon 10 e intron 4 do gene RHD foram testadas por meio da reação em cadeia da polimerase alelo-específica (AS-PCR convencional. Os resultados da genotipagem fetal foram comparados com a tipagem sangüínea convencional no período neonatal. RESULTADOS: Quinze amostras foram obtidas no primeiro trimestre, 37 no segundo trimestre e 29 no terceiro trimestre. Houve falha de amplificação em 6 amostras. A concordância entre os resultados da genotipagem e da tipagem neonatal foi de 97,3%, sensibilidade de 98,3% e especificidade de 93,8%. CONCLUSÃO: AS-PCR convencional é um método com bom desempenho para a genotipagem RHD fetal por meio da análise do plasma materno, mesmo em uma

  12. Low Back Pain Fact Sheet

    Science.gov (United States)

    ... Low Back Pain Fact Sheet You are here Home » Disorders » Patient & Caregiver Education » Fact Sheets Low Back Pain Fact Sheet What ... reduction among workers using lumbar support belts, many companies that have ... training and ergonomic awareness programs. The reported injury reduction ...

  13. The Physics of Ice Sheets

    Science.gov (United States)

    Bassis, J. N.

    2008-01-01

    The great ice sheets in Antarctica and Greenland are vast deposits of frozen freshwater that contain enough to raise sea level by approximately 70 m if they were to completely melt. Because of the potentially catastrophic impact that ice sheets can have, it is important that we understand how ice sheets have responded to past climate changes and…

  14. Living on three time scales: the dynamics of plasma cell and antibody populations illustrated for hepatitis a virus.

    Science.gov (United States)

    Andraud, Mathieu; Lejeune, Olivier; Musoro, Jammbe Z; Ogunjimi, Benson; Beutels, Philippe; Hens, Niel

    2012-01-01

    Understanding the mechanisms involved in long-term persistence of humoral immunity after natural infection or vaccination is challenging and crucial for further research in immunology, vaccine development as well as health policy. Long-lived plasma cells, which have recently been shown to reside in survival niches in the bone marrow, are instrumental in the process of immunity induction and persistence. We developed a mathematical model, assuming two antibody-secreting cell subpopulations (short- and long-lived plasma cells), to analyze the antibody kinetics after HAV-vaccination using data from two long-term follow-up studies. Model parameters were estimated through a hierarchical nonlinear mixed-effects model analysis. Long-term individual predictions were derived from the individual empirical parameters and were used to estimate the mean time to immunity waning. We show that three life spans are essential to explain the observed antibody kinetics: that of the antibodies (around one month), the short-lived plasma cells (several months) and the long-lived plasma cells (decades). Although our model is a simplified representation of the actual mechanisms that govern individual immune responses, the level of agreement between long-term individual predictions and observed kinetics is reassuringly close. The quantitative assessment of the time scales over which plasma cells and antibodies live and interact provides a basis for further quantitative research on immunology, with direct consequences for understanding the epidemiology of infectious diseases, and for timing serum sampling in clinical trials of vaccines.

  15. Plasma selenium and risk of dysglycemia in an elderly French population: results from the prospective Epidemiology of Vascular Ageing Study

    Directory of Open Access Journals (Sweden)

    Hininger-Favier Isabelle

    2010-03-01

    Full Text Available Abstract Background A preventive role of selenium on the risk of diabetes has been reported and ascribed to the "insulin-like" activity of selenium and the antioxidant properties of the selenoenzymes. By contrast, data from cross-sectional studies and clinical trials have suggested an adverse effect of high selenium status and selenium supplementation on type-2 diabetes risk. Given these controversial results, we investigated prospectively the relationship between baseline plasma selenium concentration and occurrence of dysglycemia (impaired fasting glucose or type 2 diabetes in an elderly French cohort. Methods The Epidemiology of Vascular Ageing (EVA study (n = 1389, 59-71 years is a 9-year longitudinal study in which, fasting plasma glucose was measured at baseline, 2, 4 and 9 years. Analyses were performed on 1162 participants with complete data. Results At baseline plasma selenium mean levels were 1.08 (0.21 μmol/l in men and 1.10 (0.20 μmol/l in women. During the 9-year follow-up, 127 cases of dysglycemia occurred. A significant interaction was found between plasma selenium and sex. Risk of dysglycemia was significantly lower in men with plasma selenium in the highest tertile (T3:1.19-1.97 compared to those in the lowest tertile (T1:0.18-1.00 [HR = 0.48 (0.25-0.92], but no significant relationship was observed in women. After controlling for socio-demographic factors, lifestyle factors, cardiovascular diseases, body mass index, hypertension and lipid profile, plasma selenium remained marginally significantly associated with occurrence of dysglycemia in men [T3 vs. T1, HR = 0.50 (0.24-1.04] and unrelated in women. Conclusions This prospective study suggests a sex-specific protective effect of higher selenium status at baseline on later occurrence of dysglycemia.

  16. Rolling Up a Monolayer MoS2 Sheet.

    Science.gov (United States)

    Meng, Jianling; Wang, Guole; Li, Xiaomin; Lu, Xiaobo; Zhang, Jing; Yu, Hua; Chen, Wei; Du, Luojun; Liao, Mengzhou; Zhao, Jing; Chen, Peng; Zhu, Jianqi; Bai, Xuedong; Shi, Dongxia; Zhang, Guangyu

    2016-07-01

    MoS2 nanoscrolls are formed by argon plasma treatment on monolayer MoS2 sheet. The nanoscale scroll formation is attributed to the partial removal of top sulfur layer in MoS2 during the argon plasma treatment process. This convenient, solvent-free, and high-yielding nanoscroll formation technique is also feasible for other 2D transition metal dichalcogenides.

  17. Dynamic of Current Sheets and Their Associated Particle Energization

    Energy Technology Data Exchange (ETDEWEB)

    Li, Hui [Los Alamos National Laboratory; Guo, Fan [Los Alamos National Laboratory; Makwan, Kirit [Univ. Chicago; Li, Xiaocan [Los Alamos National Laboratory; Zhandrin, Vladimir [Univ. Washington; Daughton, William Scott [Los Alamos National Laboratory

    2015-08-19

    Magnetic reconnection in current sheets has relevance to Earth's magnetosphere, solar flares, high-energy astrophysics (pulsar wind nebula (e.g. Crab Nebula), gamma-ray bursts, black hole jets), and laboratory plasma/fusion. Data are shown for several cases with varying values of configuration energy Ec and β. Several conclusions were drawn: Depending on the “configuration energy”, the formation, shape, and lifetime of current sheets can vary. Plasma condition (configuration, β, driving, etc.) strongly affect the efficiency of particle acceleration. For low β and general “configuration energy”, particle heating is expected. For low β, large and long-lived current sheets, it is possible to produce highly non-thermal particles via collisionless plasmoid reconnection.

  18. Reducing slide sheet injury.

    Science.gov (United States)

    Varcin-Coad, Lynn

    2008-12-01

    Slide sheets are often stated to be the cause of hand and forearm injuries. While there are many other possible reasons injuries to nursing staff, carer and client occur, the most important linking factors relating to musculoskeletal disorders and manual handling of people is the ongoing inappropriateness or lack of suitably designed and equipped work areas. As physiotherapist Lynn Varcin-Coad writes, staff are bearing the brunt of inefficiencies of design and lack of high order risk control.

  19. Plasma Alkylresorcinols Reflect Gluten Intake and Distinguish between Gluten-Rich and Gluten-Poor Diets in a Population at Risk of Metabolic Syndrome.

    Science.gov (United States)

    Lind, Mads V; Madsen, Mia L; Rumessen, Jüri J; Vestergaard, Henrik; Gøbel, Rikke J; Hansen, Torben; Lauritzen, Lotte; Pedersen, Oluf B; Kristensen, Mette; Ross, Alastair B

    2016-10-01

    Many patients with celiac disease experience difficulties in adherence to a gluten-free diet. Methods for testing compliance to a gluten-free diet are costly and cumbersome. Thus, a simple biomarker of gluten intake is needed in a clinical setting and will be useful for epidemiologic studies investigating wider effects of gluten intake. The aim was to evaluate plasma total alkylresorcinol concentrations as a measure of gluten intake. In this randomized, controlled, crossover intervention study in 52 Danish adults with features of the metabolic syndrome, we compared 8 wk of a gluten-rich and gluten-poor diet separated by a washout period of ≥6 wk. We measured fasting plasma concentrations of alkylresorcinols to determine if they reflected differences in gluten intake as a secondary outcome of the original study. In addition, we investigated in 118 Danish adults the cross-sectional association between self-reported gluten intake and plasma alkylresorcinols in the same and a similar study at baseline. We used mixed-model ANCOVA for examining treatment effects, a classification tree to determine compliance to the gluten-poor diet, and linear regression models for examining baseline correlation between plasma alkylresorcinol concentrations and gluten intake. Plasma total alkylresorcinols decreased more during the gluten-poor period (geometric mean: -124.8 nmol/L; 95% CI: -156.5, -93.0 nmol/L) than in the gluten-rich period (geometric mean: -31.8 nmol/L; 95% CI: -63.1, -0.4 nmol/L) (P gluten intake (P gluten-free diet as well as to help investigations into the possible effects of gluten in the wider population. This trial was registered at www.clinicaltrials.gov as NCT017119913 and NCT01731366. © 2016 American Society for Nutrition.

  20. Development of a population pharmacokinetic model to describe azithromycin whole-blood and plasma concentrations over time in healthy subjects.

    Science.gov (United States)

    Pene Dumitrescu, T; Anic-Milic, T; Oreskovic, K; Padovan, J; Brouwer, K L R; Zuo, P; Schmith, V D

    2013-07-01

    Azithromycin (AZI), a broad-spectrum antibiotic, accumulates in polymorphonuclear cells and peripheral blood mononuclear cells. The distribution of AZI in proinflammatory cells may be important to the anti-inflammatory properties. Previous studies have described plasma AZI pharmacokinetics. The objective of this study was to describe the pharmacokinetics of AZI in whole blood (concentration in whole blood [Cb]) and plasma (concentration in plasma [Cp]) of healthy subjects. In this study, 12 subjects received AZI (500 mg once a day for 3 days). AZI Cb and Cp were quantified in serial samples collected up to 3 weeks after the last dose and analyzed using noncompartmental and compartmental methods. After the last dose, Cb was greater than Cp. Importantly, Cb, but not Cp, was quantifiable in all but one subject at 3 weeks. The blood area under the curve during a 24-h dosing interval (AUC24) was ∼2-fold greater than the plasma AUC24, but simulations suggested that Cb was not at steady state by day 3. Upon exploration of numerous models, an empirical 3-compartment model adequately described Cp and Cb, but Cp was somewhat underestimated. Intercompartmental clearance (CL; likely representing cells) was lower than apparent oral CL (18 versus 118 liters/h). Plasma, peripheral, and cell compartmental volumes were 439 liters, 2,980 liters, and 3,084 liters, respectively. Interindividual variability in CL was low (26.2%), while the volume of distribution variability was high (107%). This is the first report to describe AZI Cb in healthy subjects, the distribution parameters between Cp and Cb, and AZI retention in blood for up to 3 weeks following 3 daily doses. The model can be used to predict Cb from Cp for AZI under various dosing regimens. (This study has been registered at ClinicalTrials.gov under registration no. NCT01026064.).

  1. Large-Scale Structure of Magnetospheric Plasma

    Science.gov (United States)

    Moore, T. E.; Delcourt, D. C.

    1995-01-01

    Recent investigations of magnetospheric plasma structure are summarized under the broad categories of empirical models, transport across boundaries, formation, and dynamics of the plasma sheet. This report reviews work in these areas during the period 1991 to 1993. Fully three-dimensional empirical models and simulations have become important contributors to our understanding of the magnetospheric system. Some new structural concepts have appeared in the literature: the 'entry boundary' and 'geo-pause', the plasma sheet 'region 1 vortices', the 'low-energy layer', the 'adia-baticity boundary' or 'wall region', and a region in the tail to which we refer as the 'injection port'. Traditional structural concepts have also been the subject of recent study, notably the plasmapause, the magnetopause, and the plasma sheet. Significant progress has been made in understanding the nature of plasma sheet formation and dynamics, but the acceleration of electrons to high energy remains somewhat mysterious.

  2. Sources of Pressure in Titan's Plasma Environment

    CERN Document Server

    Achilleos, N; Bertucci, C; Guio, P; Romanelli, N; Sergis, N

    2013-01-01

    In order to analyze varying plasma conditions upstream of Titan, we have combined a physical model of Saturn's plasmadisk with a geometrical model of the oscillating current sheet. During modeled oscillation phases where Titan is furthest from the current sheet, the main sources of plasma pressure in the near-Titan space are the magnetic pressure and, for disturbed conditions, the hot plasma pressure. When Titan is at the center of the sheet, the main source is the dynamic pressure associated with Saturn's cold, subcorotating plasma. Total pressure at Titan (dynamic plus thermal plus magnetic) typically increases by a factor of five as the current sheet center is approached. The predicted incident plasma flow direction deviates from the orbital plane of Titan by < 10 deg. These results suggest a correlation between the location of magnetic pressure maxima and the oscillation phase of the plasmasheet.

  3. Polymorphisms of the coagulation factor Ⅶ gene and its plasma levels in relation to acute cerebral infarction differences in allelic frequencies between Chinese Han and European populations

    Institute of Scientific and Technical Information of China (English)

    康文英; 王鸿利; 熊立凡; 王学锋; 储海燕; 璩斌; 刘湘帆; 尹俊; 段宝华; 王振义

    2004-01-01

    Background Coagulation factor Ⅶ (F Ⅶ) levels in plasma are usually related to ischemic heart disease (IHD) and cerebral infarction shares many of the risk factors related to IHD. Is there any relationship between factor Ⅶ and cerebral infarction? We investigated the relationship between F Ⅶ and acute cerebral infarction and reported genotype frequencies and allelic frequencies of FⅦ gene polymorphisms in the Chinese Han population.Methods We recruited 62 patients with acute cerebral infarction confirmed by magnetic resonance imaging (MRI) from Ruijin Hospital, and 149 age-matched patients clinically free of vascular disease to act as controls. All of them were unrelated, and were from the Chinese Han population. FⅦ coagulant activity (FⅦc) was determined using an clotting assay, activated FⅦ (FⅦa) and FⅦ Ag were assayed using enzyme immunoassay kits. The FⅦ gene polymorphisms to be detected included-401G/T, -402G/A, 5'F7A1/A2, IVS7 and R353Q. 5'F7 and IVS7 were revealed by means of a PCR and direct agarose gel electrophoresis. The rest were examined by a polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). Results The results showed that FⅦc, FⅦAg and FⅦa were higher in the acute cerebral infarction group than in the control group (P<0.01, P<0.05, P<0.05, respectively). There were no significant differences in the genotype frequencies of FⅦ gene polymorphisms between the two groups. The allelic frequencies in the Chinese Han population were as follows: -401G/T (96.64/3.36), -402G/A (52.01/47.99), 5'F7A1/A2(96.64/3.36), IVS7 H5/H6/H7/H8 (0.34/52.35/46.98/0.34) and R353Q (95.64/4.36). There were significant differences (P<0.01, P<0.001, P<0.001, P<0.001, P<0.001, respectively) in these allelic frequencies between the Chinese Han and European populations.Conclusions The results indicate that increased plasma FⅦ levels may contribute to thrombosis in cerebral infarction. And there was no significant difference

  4. Observational and genetic plasma YKL-40 and cancer in 96,099 individuals from the general population

    DEFF Research Database (Denmark)

    Kjaergaard, Alisa D; Nordestgaard, Børge G; Johansen, Julia S

    2015-01-01

    , 913 developed lung cancer, 2,863 women developed breast cancer, 1,557 men developed prostate cancer and 5,146 individuals developed other cancer. Follow-up was 100% complete. Multifactorially and CRP adjusted hazard ratio (HR) for gastrointestinal cancer was 1.82 (95%CI, 1.16-2.86) for 96-100% versus...... 0-33% YKL-40 percentile category. Corresponding HR were 1.71 (0.95-3.07) for lung cancer, but insignificant for breast cancer, prostate cancer and other cancers. CHI3L1 rs4950928 genotype was associated with plasmaYKL-40 levels, but not with risk of any cancer category. For gastrointestinal cancer......Plasma YKL-40 is high in patients with cancer and in individuals who later develop cancer. Whether YKL-40 is only a marker or indeed a cause of cancer is presently unknown. We tested the hypothesis that observationally and genetically, high plasma YKL-40 is associated with high risk of cancer...

  5. Total plasma homocysteine, folate, and vitamin b12 status in healthy Iranian adults: the Tehran homocysteine survey (2003–2004/a cross – sectional population based study

    Directory of Open Access Journals (Sweden)

    Bandarian Fatemeh

    2006-02-01

    Full Text Available Abstract Background Elevated plasma total homocysteine is an independent risk factor for cardiovascular disease and a sensitive marker of the inadequate vitamin B12 and folate insufficiency. Folate and vitamin B12 have a protective effect on cardiovascular disease. This population based study was conducted to evaluate the plasma total homocysteine, folate, and vitamin B12 in healthy Iranian individuals. Methods This study was a part of the Cardiovascular Risk Factors Survey in the Population Lab Region of Tehran University has been designed and conducted based on the methodology of MONICA/WHO Project. A total of 1214 people aged 25–64 years, were recruited and assessed regarding demographic characteristics, homocysteine, folate, and vitamin B12 levels with interview, questionnaires, examination and blood sampling. Blood samples were gathered and analyzed according to standard methods. Results The variables were assessed in 1214 participants including 428 men (35.3% and 786 women (64.7%. Age-adjusted prevalence of hyperhomocysteinemia (Hcy≥15 μmol/L was 73.1% in men and 41.07% in women (P Conclusion These results revealed that the prevalence of hyperhomocysteinemia, low folate and vitamin B12 levels are considerably higher than other communities. Implementation of preventive interventions such as food fortification with folic acid is necessary.

  6. The lysosomal N-acetyl-beta-D-glucosaminidase (NAG) isoenzymes in plasma: study of distribution in a general population by a simple routine chromatofocusing procedure.

    Science.gov (United States)

    Goi, G; Bairati, C; Roggi, C; Maccarini, L; Tettamanti, G; Meloni, C; Lombardo, A

    1993-11-30

    We have adapted for routine analysis a pre-existing method for separating the three major N-acetyl-beta-D-glucosaminidase (NAG) isoenzyme forms--A, B+I1 and I2--by chromatofocusing followed by fluorimetric assay of the enzyme activity. This method combines good resolution, accurate quantification of the different isoenzymes and high reproducibility with an acceptable degree of analytical precision. We have applied it to studying the isoenzyme levels in the plasma of a general population of 417 subjects and have analysed these enzyme activities as functions of age, sex, body mass and declared alcohol consumption. Unlike the levels of unfractionated enzyme, levels of all the isoenzymes were higher in men than in women at all ages except in the 20-29 year group. Isoenzyme I2 showed the greatest sex difference. On the whole, with increasing age, both sexes showed more or less regular increases in plasma levels of all the isoenzymes. We also found significant correlations for the population as a whole with age and with body mass index. The only significant correlation with alcohol consumption was for B+I1 in men.

  7. Experimental study of the dynamics of a thin current sheet

    Science.gov (United States)

    Gekelman, W.; DeHaas, T.; Van Compernolle, B.; Daughton, W.; Pribyl, P.; Vincena, S.; Hong, D.

    2016-05-01

    Many plasmas in natural settings or in laboratory experiments carry currents. In magnetized plasmas the currents can be narrow field-aligned filaments as small as the electron inertial length ≤ft(\\tfrac{c}{{ω }pe}\\right) in the transverse dimension or fill the entire plasma column. Currents can take the form of sheets, again with the transverse dimension the narrow one. Are laminar sheets of electric current in a magnetized plasma stable? This became an important issue in the 1960s when current-carrying plasmas became key in the quest for thermonuclear fusion. The subject is still under study today. The conditions necessary for the onset for tearing are known, the key issue is that of the final state. Is there a final state? One possibility is a collection of stable tubes of current. On the other hand, is the interaction between the current filaments which are the byproduct endless, or does it go on to become chaotic? The subject of three-dimensional current systems is intriguing, rich in a variety of phenomena on multiple scale sizes and frequencies, and relevant to fusion studies, solar physics, space plasmas and astrophysical phenomena. In this study a long (δz = 11 m) and narrow (δx = 1 cm, δy = 20 cm) current sheet is generated in a background magnetoplasma capable of supporting Alfvén waves. The current is observed to rapidly tear into a series of magnetic islands when viewed in a cross-sectional plane, but they are in essence three-dimensional flux ropes. At the onset of the current, magnetic field line reconnection is observed between the flux ropes. The sheet on the whole is kink-unstable, and after kinking exhibits large-scale, low-frequency (f ≪ f ci ) rotation about the background field with an amplitude that grows with distance from the source of the current. Three-dimensional data of the magnetic and electric fields is acquired throughout the duration of the experiment and the parallel resistivity is derived from it. The parallel

  8. Dynamo-driven plasmoid formation from a current-sheet instability

    CERN Document Server

    Ebrahimi, F

    2016-01-01

    Axisymmetric current-carrying plasmoids are formed in the presence of nonaxisymmetric fluctuations during nonlinear three-dimensional resistive MHD simulations in a global toroidal geometry. We utilize the helicity injection technique to form an initial poloidal flux in the presence of a toroidal guide field. As helicity is injected, two types of current sheets are formed from 1) the oppositely directed field lines in the injector region (primary reconnecting current sheet), and 2) the poloidal flux compression near the plasma edge (edge current sheet). We first find that nonaxisymmetic fluctuations arising from the current-sheet instability isolated near the plasma edge have tearing parity but can nevertheless grow fast (on the poloidal Alfven time scale). These modes saturate by breaking up the current sheet. Second, for the first time a dynamo poloidal flux amplification is observed at the reconnetion site (in the region of the oppositely directed magnetic field). This fluctuation-induced flux amplificatio...

  9. Plasma Levels of Risk-Variant APOL1 Do Not Associate with Renal Disease in a Population-Based Cohort.

    Science.gov (United States)

    Kozlitina, Julia; Zhou, Haihong; Brown, Patricia N; Rohm, Rory J; Pan, Yi; Ayanoglu, Gulesi; Du, Xiaoyan; Rimmer, Eric; Reilly, Dermot F; Roddy, Thomas P; Cully, Doris F; Vogt, Thomas F; Blom, Daniel; Hoek, Maarten

    2016-10-01

    Two common missense variants in APOL1 (G1 and G2) have been definitively linked to CKD in black Americans. However, not all individuals with the renal-risk genotype develop CKD, and little is known about how APOL1 variants drive disease. Given the association of APOL1 with HDL particles, which are cleared by the kidney, differences in the level or quality of mutant APOL1‑HDL particles could be causal for disease and might serve as a useful risk stratification marker. We measured plasma levels of G0 (low risk), G1, and G2 APOL1 in 3450 individuals in the Dallas Heart Study using a liquid chromatography-MS method that enabled quantitation of the different variants. Additionally, we characterized native APOL1‑HDL from donors with no or two APOL1 risk alleles by size-exclusion chromatography and analysis of immunopurified APOL1‑HDL particles. Finally, we identified genetic loci associated with plasma APOL1 levels and tested for APOL1-dependent association with renal function. Although we replicated the previous association between APOL1 variant status and renal function in nondiabetic individuals, levels of circulating APOL1 did not associate with microalbuminuria or GFR. Furthermore, the size or known components of APOL1‑HDL did not consistently differ in subjects with the renal-risk genotype. Genetic association studies implicated variants in loci harboring haptoglobin-related protein (HPR), APOL1, and ubiquitin D (UBD) in the regulation of plasma APOL1 levels, but these variants did not associate with renal function. Collectively, these data demonstrate that the risk of renal disease associated with APOL1 is probably not related to circulating levels of the mutant protein.

  10. Association between fasting plasma triglycerides, all-cause and cardiovascular mortality in Czech population. Results from the HAPIEE study.

    Science.gov (United States)

    Pikhart, H; Hubáček, J A; Peasey, A; Kubínová, R; Bobák, M

    2015-01-01

    Dyslipidemia is the risk factor of cardiovascular disease, but the relationship between the plasma triglyceride (TG) levels and total/cardiovascular mortality has not yet been analyzed in Slavs. The aim of our study was to analyze the association between the fasting TG levels and all-cause/cardiovascular mortality. We have examined 3,143 males and 3,650 females, aged 58.3+/-7.1 years. 729 deaths (274 cardiovascular deaths) have been registered during up to 11.8 years of follow-up. Age-sex adjusted all-cause mortality was higher in individuals with TG values 3.01-4.00 mmol/l (HR 1.37, 95 % CI 1.02-1.83, P=0.035) and over 4.00 mmol/l (HR 1.66, 95 % CI 1.21-2.27, P=0.002) when compared with a reference group (TG 1.41-1.80 mmol/l). Elevated risk remains significant when adjusted for education, marital status and unemployment. When further adjusted for smoking, BMI and dyslipidemia interventions, HR for those in above 4.00 mmol/l group decreased (1.42, P=0.04). The results have been similar when cardiovascular mortality has been examined, however, results reached statistical significance only for the TG over 4.0 mmol/l (P=0.028). Our results confirmed that enhanced plasma levels of plasma triglycerides are dose dependently associated with increased risk of all-cause mortality, however, it seems that individuals with TG values 1.8-3.0 mmol/l are not in higher risk of death.

  11. Perfluorinated compounds in human serum and seminal plasma from an urban and rural population in Sri Lanka

    Energy Technology Data Exchange (ETDEWEB)

    Guruge, Keerthi; Miyazaki, Shigeru; Yamanaka, Noriko [National Institute of Animal Health, Tsukuba (Japan); Taniyasu, Sacgu; Yamashita, Nobuyoshi [National Institute of Advance Industrial and Technology, Tsukuba (Japan); Wijeratna, S.; Seneviratne, H. [Colombo Univ. (Sri Lanka)

    2004-09-15

    Fluorinated organic compounds (FOCs) have been used for variety of industrial applications such as surfactants, adhesives, insecticides, and their global production increase since 1970s. These compounds repel both water and oil. The high-energy carbon-fluorine covalent bonds in FOCs are strong enough to have high persistency in the environment. These compounds emerged as priory environmental pollutants since they are found in various biota throughout the world. Human contamination of some FOCs was reported mostly in developed countries such as USA, Japan and from Europe. In the present study, we report 10 FOCs in human serum including seminal plasma for the first time, collected from volunteers from Sri Lanka.

  12. Modelling the Antarctic Ice Sheet

    DEFF Research Database (Denmark)

    Pedersen, Jens Olaf Pepke; Holm, A.

    2015-01-01

    The Antarctic ice sheet is a major player in the Earth’s climate system and is by far the largest depository of fresh water on the planet. Ice stored in the Antarctic ice sheet (AIS) contains enough water to raise sea level by about 58 m, and ice loss from Antarctica contributed significantly...... Science) Antarctic Ice Sheet (DAIS) model (Shaffer 2014) is forced by reconstructed time series of Antarctic temperature, global sea level and ocean subsurface temperature over the last two glacial cycles. In this talk a modelling work of the Antarctic ice sheet over most of the Cenozoic era using...

  13. Neutral sheet crossings in the distant magnetotail

    Energy Technology Data Exchange (ETDEWEB)

    Heikkila, W.J.; Slavin, J.A.; Smith, E.J.; Baker, D.N.; Zwickl, R.D.

    1985-01-01

    We have analyzed the magnetic field data from ISEE-3 in the distant magnetotail for 18 crossings of the cross-tail current sheet (or so-called natural sheet) to determine the direction of the normal component B/sub z/. The crossings occurred near the middle of the aberrated magnetotail (0 < y < 30 R/sub e, -10 < z < 5) in GSM coordinates, at a distance of about 220 R/sub e/, January 28 to February 12, 1983; in each case the plasma flow velocity was tailward. In 2 cases we found B/sub z/ negative (southward), as would be required with a magnetic neutral line (reconnection line) earthward of the spacecraft. In 12 cases B/sub z/ was clearly northward (B/sub z/ > 0.4 nT), consistent with closed field lines connected to the earth. In 3 cases B/sub z/ was very close to zero; in several instances there was structure in B/sub y/, suggesting localized currents with x or z directions. One may have been a magnetopause crossing. The strong preponderance of northward B/sub z/ favors a model of the magnetotail which is dominated by boundary layer plasma, flowing tailward on closed magnetic field lines, which requires the existence of an electric field in the sense from dusk to dawn. 37 refs., 15 figs., 1 tab.

  14. Solar wind and substorm excitation of the wavy current sheet

    Science.gov (United States)

    Forsyth, C.; Lester, M.; Fear, R. C.; Lucek, E.; Dandouras, I.; Fazakerley, A. N.; Singer, H.; Yeoman, T. K.

    2009-06-01

    Following a solar wind pressure pulse on 3 August 2001, GOES 8, GOES 10, Cluster and Polar observed dipolarizations of the magnetic field, accompanied by an eastward expansion of the aurora observed by IMAGE, indicating the occurrence of two substorms. Prior to the first substorm, the motion of the plasma sheet with respect to Cluster was in the ZGSM direction. Observations following the substorms show the occurrence of current sheet waves moving predominantly in the -YGSM direction. Following the second substorm, the current sheet waves caused multiple current sheet crossings of the Cluster spacecraft, previously studied by Zhang et al. (2002). We further this study to show that the velocity of the current sheet waves was similar to the expansion velocity of the substorm aurora and the expansion of the dipolarization regions in the magnetotail. Furthermore, we compare these results with the current sheet wave models of Golovchanskaya and Maltsev (2005) and Erkaev et al. (2008). We find that the Erkaev et al. (2008) model gives the best fit to the observations.

  15. Solar wind and substorm excitation of the wavy current sheet

    Directory of Open Access Journals (Sweden)

    C. Forsyth

    2009-06-01

    Full Text Available Following a solar wind pressure pulse on 3 August 2001, GOES 8, GOES 10, Cluster and Polar observed dipolarizations of the magnetic field, accompanied by an eastward expansion of the aurora observed by IMAGE, indicating the occurrence of two substorms. Prior to the first substorm, the motion of the plasma sheet with respect to Cluster was in the ZGSM direction. Observations following the substorms show the occurrence of current sheet waves moving predominantly in the −YGSM direction. Following the second substorm, the current sheet waves caused multiple current sheet crossings of the Cluster spacecraft, previously studied by Zhang et al. (2002. We further this study to show that the velocity of the current sheet waves was similar to the expansion velocity of the substorm aurora and the expansion of the dipolarization regions in the magnetotail. Furthermore, we compare these results with the current sheet wave models of Golovchanskaya and Maltsev (2005 and Erkaev et al. (2008. We find that the Erkaev et al. (2008 model gives the best fit to the observations.

  16. Noncoordinate expression of J-chain and Blimp-1 define nurse shark plasma cell populations during ontogeny.

    Science.gov (United States)

    Castro, Caitlin D; Ohta, Yuko; Dooley, Helen; Flajnik, Martin F

    2013-11-01

    B-lymphocyte-induced maturation protein 1 (Blimp-1) is the master regulator of plasma cell development, controlling genes such as those encoding J-chain and secretory Ig heavy chain. However, some mammalian plasma cells do not express J-chain, and mammalian B1 cells secrete "natural" IgM antibodies without upregulating Blimp-1. While these results have been controversial in mammalian systems, here we describe subsets of normally occurring Blimp-1(-) antibody-secreting cells in nurse sharks, found in lymphoid tissues at all ontogenic stages. Sharks naturally produce large amounts of both pentameric (classically "19S") and monomeric (classically "7S") IgM, the latter an indicator of adaptive immunity. Consistent with the mammalian paradigm, shark Blimp-1 is expressed in splenic 7S IgM-secreting cells, though rarely detected in the J-chain(+) cells producing 19S IgM. Although IgM transcript levels are lower in J-chain(+) cells, these cells nevertheless secrete 19S IgM in the absence of Blimp-1, as demonstrated by ELISPOT and metabolic labeling. Additionally, cells in the shark BM equivalent (epigonal) are Blimp-1(-). Our data suggest that, in sharks, 19S-secreting cells and other secreting memory B cells in the epigonal are maintained for long periods without Blimp-1, but like in mammals, Blimp-1 is required for terminating the B-cell program following an adaptive immune response in the spleen.

  17. Heritabilities, apolipoprotein E, and effects of inbreeding on plasma lipids in a genetically isolated population: The Erasmus Rucphen family study

    NARCIS (Netherlands)

    A.J. Isaacs (Aaron); F.A. Sayed-Tabatabaei (Fakhredin); Y.S. Aulchenko (Yurii); M.C. Zillikens (Carola); E.J.G. Sijbrands (Eric); A.F.C. Schut (Anna); W.P.F. Rutten (Wim); H.A.P. Pols (Huib); J.C.M. Witteman (Jacqueline); B.A. Oostra (Ben); P. Tikka-Kleemola (Päivi)

    2007-01-01

    textabstractDespite considerable progress in unravelling the genetic basis of dyslipidemias, most findings are based on families with extreme phenotypes. We studied lipid levels in an extended pedigree ascertained irrespective of phenotype from the population of a recent genetic isolate in the Nethe

  18. Influence mechanism of low-dose ionizing radiation on Escherichia coli DH5α population based on plasma theory and system dynamics simulation.

    Science.gov (United States)

    Sun, Yi; Hu, Dawei; Li, Liang; Jing, Zheng; Wei, Chuanfeng; Zhang, Lantao; Fu, Yuming; Liu, Hong

    2016-01-01

    It remains a mystery why the growth rate of bacteria is higher in low-dose ionizing radiation (LDIR) environment than that in normal environment. In this study, a hypothesis composed of environmental selection and competitive exclusion was firstly proposed from observed phenomena, experimental data and microbial ecology. Then a LDIR environment simulator (LDIRES) was built to cultivate a model organism of bacteria, Escherichia coli (E. coli) DH5α, the accurate response of bacterial population to ionizing radiation intensity variation was measured experimentally, and then the precise relative dosage of ionizing radiation E. coli DH5α population received was calculated by finite element analysis based on drift-diffusion equations of plasma. Finally, a highly valid mathematical model expressing the relationship between E. coli DH5α population and LDIR intensity was developed by system dynamics based on hypotheses, experimental data and microbial ecology. Both experiment and simulation results clearly showed that the E. coli DH5α individuals with greater specific growth rate and lower substrate consumption coefficient would adapt and survive in LDIR environment and those without such adaptability were finally eliminated under the combined effects of ionizing radiation selection and competitive exclusion.

  19. Genetic relationship between serum pregnancy-associated plasma protein-A gene polymorphism and ischemic cerebrovascular disease in a Northern Han Chinese population

    Institute of Scientific and Technical Information of China (English)

    Haiping Wang; Yan Song; Chen Zhang; Jingjing Zhan; Rui Zhang; Haiji Wang

    2012-01-01

    The present study recruited 193 patients with ischemic cerebrovascular disease from Inpatient and Outpatient Departments at the Affiliated Hospital of Qingdao University Medical College, China from August 2008 to May 2010, as well as 120 healthy volunteers from the Medical Examination Center at the Affiliated Hospital of Qingdao University Medical College, China, who served as controls for this study.Patients and control subjects were from the Han population in northern China.Enzyme- linked immunosorbent assay analysis revealed increased levels of serum pregnancy-associated plasma protein-A (PAPP-A) in ischemic cerebrovascular disease patients compared with healthy controls.In addition, the patients exhibited greater frequency of genotype CC and C alleles in a missense A/C (Tyr/Ser) polymorphism (dbSNP: rs7020782) of exon 14 in the PAPP-A gene.Multiple-factor logistic regression analysis on correction of age, gender, history of smoking, hypertension, diabetes mellitus, hypercholesteremia, and ischemic stroke family history showed that the risk for ischemic cerebrovascular disease in the population without the A allele at the A/C genetic locus in exon 14 of the PAPP-A was 2-folds greater than the population expressing the A allele.These experimental findings suggested that ischemic cerebrovascular disease correlated with the C allele in exon 14 of PAPP-A.In addition, the A allele is likely a protective gene; individuals carrying the A allele were less prone to ischemic cerebrovascular disease compared with individuals without the A allele.

  20. Interethnic variability of plasma paraoxonase (PON1) activity towards organophosphates and PON1 polymorphisms among Asian populations--a short review.

    Science.gov (United States)

    Mohamed Ali, Safiyya; Chia, Sin Eng

    2008-08-01

    Organophosphate (OP) poisoning is a progressively worrying phenomenon as worldwide pesticide production and consumption has doubled. On average, WHO estimates that 3% of agricultural workers in developing Asian countries suffer an episode of pesticide poisoning every year. Furthermore, the threat of OP usage in terrorism is existent, as seen by the subway tragedy in Tokyo in 1995 where sarin was used. Despite these alarming facts, there is currently no global system to track poisonings related to pesticide use. Human serum paraoxonase (PON1) is the enzyme that hydrolyses OP compounds. Serum PON1 levels and activity vary widely among different ethnic populations. Two commonly studied polymorphisms of PON1 are PON1Q192R and PON1L55M. PON1R192 hydrolyses paraoxon faster than PON1Q192 but hydrolyses diazoxon, sarin and soman eight times slower, and vice versa. PON1M55 has lower plasma levels of PON1 than PON1L55. As the prevalence of the different alleles and genotypic distribution vary between the Asian populations we studied, we propose the necessity to study PON1 polymorphisms and its role in OP toxicity in Asian populations. This would help safeguard the proper care of agricultural workers who might be affected by OP poisoning, and alert relevant anti biological terrorism agencies on possible risks involved in the event of an OP attack and provide effective counter measures.

  1. Osteopathic manipulative therapy induces early plasma cytokine release and mobilization of a population of blood dendritic cells.

    Science.gov (United States)

    Walkowski, Stevan; Singh, Manindra; Puertas, Juan; Pate, Michelle; Goodrum, Kenneth; Benencia, Fabian

    2014-01-01

    It has been claimed that osteopathic manipulative treatment (OMT) is able to enhance the immune response of individuals. In particular, it has been reported that OMT has the capability to increase antibody titers, enhance the efficacy of vaccination, and upregulate the numbers of circulating leukocytes. Recently, it has been shown in human patients suffering chronic low back pain, that OMT is able to modify the levels of cytokines such as IL-6 and TNF-α in blood upon repeated treatment. Further, experimental animal models show that lymphatic pump techniques can induce a transient increase of cytokines in the lymphatic circulation. Taking into account all these data, we decided to investigate in healthy individuals the capacity of OMT to induce a rapid modification of the levels of cytokines and leukocytes in circulation. Human volunteers were subjected to a mixture of lymphatic and thoracic OMT, and shortly after the levels of several cytokines were evaluated by protein array technology and ELISA multiplex analysis, while the profile and activation status of circulating leukocytes was extensively evaluated by multicolor flow cytometry. In addition, the levels of nitric oxide and C-reactive protein (CRP) in plasma were determined. In this study, our results show that OMT was not able to induce a rapid modification in the levels of plasma nitrites or CRP or in the proportion or activation status of central memory, effector memory or naïve CD4 and CD8 T cells. A significant decrease in the proportion of a subpopulation of blood dendritic cells was detected in OMT patients. Significant differences were also detected in the levels of immune molecules such as IL-8, MCP-1, MIP-1α and most notably, G-CSF. Thus, OMT is able to induce a rapid change in the immunological profile of particular circulating cytokines and leukocytes.

  2. Osteopathic manipulative therapy induces early plasma cytokine release and mobilization of a population of blood dendritic cells.

    Directory of Open Access Journals (Sweden)

    Stevan Walkowski

    Full Text Available It has been claimed that osteopathic manipulative treatment (OMT is able to enhance the immune response of individuals. In particular, it has been reported that OMT has the capability to increase antibody titers, enhance the efficacy of vaccination, and upregulate the numbers of circulating leukocytes. Recently, it has been shown in human patients suffering chronic low back pain, that OMT is able to modify the levels of cytokines such as IL-6 and TNF-α in blood upon repeated treatment. Further, experimental animal models show that lymphatic pump techniques can induce a transient increase of cytokines in the lymphatic circulation. Taking into account all these data, we decided to investigate in healthy individuals the capacity of OMT to induce a rapid modification of the levels of cytokines and leukocytes in circulation. Human volunteers were subjected to a mixture of lymphatic and thoracic OMT, and shortly after the levels of several cytokines were evaluated by protein array technology and ELISA multiplex analysis, while the profile and activation status of circulating leukocytes was extensively evaluated by multicolor flow cytometry. In addition, the levels of nitric oxide and C-reactive protein (CRP in plasma were determined. In this study, our results show that OMT was not able to induce a rapid modification in the levels of plasma nitrites or CRP or in the proportion or activation status of central memory, effector memory or naïve CD4 and CD8 T cells. A significant decrease in the proportion of a subpopulation of blood dendritic cells was detected in OMT patients. Significant differences were also detected in the levels of immune molecules such as IL-8, MCP-1, MIP-1α and most notably, G-CSF. Thus, OMT is able to induce a rapid change in the immunological profile of particular circulating cytokines and leukocytes.

  3. Photovoltaics Fact Sheet

    Energy Technology Data Exchange (ETDEWEB)

    None

    2016-02-01

    This fact sheet is an overview of the Photovoltaics (PV) subprogram at the U.S. Department of Energy SunShot Initiative. The U.S. Department of Energy (DOE)’s Solar Energy Technologies Office works with industry, academia, national laboratories, and other government agencies to advance solar PV, which is the direct conversion of sunlight into electricity by a semiconductor, in support of the goals of the SunShot Initiative. SunShot supports research and development to aggressively advance PV technology by improving efficiency and reliability and lowering manufacturing costs. SunShot’s PV portfolio spans work from early-stage solar cell research through technology commercialization, including work on materials, processes, and device structure and characterization techniques.

  4. Soft Costs Fact Sheet

    Energy Technology Data Exchange (ETDEWEB)

    None

    2016-05-01

    This fact sheet is an overview of the systems integration subprogram at the U.S. Department of Energy SunShot Initiative. Soft costs can vary significantly as a result of a fragmented energy marketplace. In the U.S., there are 18,000 jurisdictions and 3,000 utilities with different rules and regulations for how to go solar. The same solar equipment may vary widely in its final installation price due to process and market variations across jurisdictions, creating barriers to rapid industry growth. SunShot supports the development of innovative solutions that enable communities to build their local economies and establish clean energy initiatives that meet their needs, while at the same time creating sustainable solar market conditions.

  5. Systems Integration Fact Sheet

    Energy Technology Data Exchange (ETDEWEB)

    None

    2016-06-01

    This fact sheet is an overview of the Systems Integration subprogram at the U.S. Department of Energy SunShot Initiative. The Systems Integration subprogram enables the widespread deployment of safe, reliable, and cost-effective solar energy technologies by addressing the associated technical and non-technical challenges. These include timely and cost-effective interconnection procedures, optimal system planning, accurate prediction of solar resources, monitoring and control of solar power, maintaining grid reliability and stability, and many more. To address the challenges associated with interconnecting and integrating hundreds of gigawatts of solar power onto the electricity grid, the Systems Integration program funds research, development, and demonstration projects in four broad, interrelated focus areas: grid performance and reliability, dispatchability, power electronics, and communications.

  6. Material Safety Data Sheets (MSDS)

    CERN Document Server

    Lalley, J

    About 250.000 Material Safety Data sheets from the U.S. Government Department of Defense MSDS database, a mirror of data from siri.uvm.edu, MSDS sheets maintained by Cornell University Environmental Health and Safety and other Cornell departments.

  7. Skill Sheets for Agricultural Machinery.

    Science.gov (United States)

    Iowa State Univ. of Science and Technology, Ames. Dept. of Agricultural Education.

    This set of 21 skill sheets for agricultural machinery was developed for use in high school and vocational school agricultural mechanics programs. Each sheet covers a single operational procedure for a piece of agricultural machinery, and includes: (1) a diagram, (2) a step-by-step operational procedure, (3) abilities or understandings taught, (4)…

  8. Analytical ice-sheet models

    NARCIS (Netherlands)

    Oerlemans, J.

    2005-01-01

    To model present-day or palaeo-ice sheets in a realistic way requires numerical methods with high spatial resolution and a comprehensive description of the relevant physical processes. Nevertheless, some basic elements of the interaction between ice sheets and climate can be investigated by simple m

  9. Tuning the mechanical properties of vertical graphene sheets through atomic layer deposition.

    Science.gov (United States)

    Davami, Keivan; Jiang, Yijie; Cortes, John; Lin, Chen; Shaygan, Mehrdad; Turner, Kevin T; Bargatin, Igor

    2016-04-15

    We report the fabrication and characterization of graphene nanostructures with mechanical properties that are tuned by conformal deposition of alumina. Vertical graphene (VG) sheets, also called carbon nanowalls (CNWs), were grown on copper foil substrates using a radio-frequency plasma-enhanced chemical vapor deposition (RF-PECVD) technique and conformally coated with different thicknesses of alumina (Al2O3) using atomic layer deposition (ALD). Nanoindentation was used to characterize the mechanical properties of pristine and alumina-coated VG sheets. Results show a significant increase in the effective Young's modulus of the VG sheets with increasing thickness of deposited alumina. Deposition of only a 5 nm thick alumina layer on the VG sheets nearly triples the effective Young's modulus of the VG structures. Both energy absorption and strain recovery were lower in VG sheets coated with alumina than in pure VG sheets (for the same peak force). This may be attributed to the increase in bending stiffness of the VG sheets and the creation of connections between the sheets after ALD deposition. These results demonstrate that the mechanical properties of VG sheets can be tuned over a wide range through conformal atomic layer deposition, facilitating the use of VG sheets in applications where specific mechanical properties are needed.

  10. Association between plasma leptin and blood pressure in two population-based samples of children and adolescents

    DEFF Research Database (Denmark)

    Grøntved, Anders; Steene-Johannessen, Jostein; Kynde, Iben

    2011-01-01

    In this study we examined the association between leptin and blood pressure in a population-based study of Danish and Norwegian children and adolescents. Because of the putative bidirectional relationship between leptin and adiposity we formally tested (i) the mediating effect of body mass index...... in the association between leptin and blood pressure, and (ii) the mediating effect of leptin in the association between body mass index and blood pressure....

  11. Association between plasma vitamin C concentrations and blood pressure in the European prospective investigation into cancer-Norfolk population-based study.

    Science.gov (United States)

    Myint, Phyo K; Luben, Robert N; Wareham, Nicholas J; Khaw, Kay-Tee

    2011-09-01

    The effect of fruit and vegetable consumption and blood pressure is unclear. A population-based cross-sectional study was conducted in 20 926 men and women aged 40 to 79 years participating in the European Prospective Investigation Into Cancer-Norfolk who completed a health questionnaire and attended a clinic from 1993 to 1997. The relationship between plasma vitamin C concentrations, as an indicator of fruit and vegetable intake, and systolic BP was examined. The magnitude of their association was assessed using dichotomized values of high (≥140 mm Hg) and low (fruit and vegetable consumption, and a lower level of blood pressure. This may provide further evidence for health benefits of dietary patterns with higher fruit and vegetable consumption.

  12. Properties of Hermean plasma belt: Numerical simulations and comparison with MESSENGER data

    Science.gov (United States)

    Herčík, David; Trávníček, Pavel M.; Å tverák, Å. těpán.; Hellinger, Petr

    2016-01-01

    Using a global hybrid model and test particle simulations we present a detailed analysis of the Hermean plasma belt structure. We investigate characteristic properties of quasi-trapped particle population characteristics and its behavior under different orientations of the interplanetary magnetic field. The plasma belt region is constantly supplied with solar wind protons via magnetospheric flanks and tail current sheet region. Protons inside the plasma belt region are quasi-trapped in the magnetic field of Mercury and perform westward drift along the planet. This region is well separated by a magnetic shell and has higher average temperatures and lower bulk proton current densities than the surrounding area. On the dayside the population exhibits loss cone distribution function matching the theoretical loss cone angle. The simulation results are in good agreement with in situ observations of MESSENGER's (MErcury Surface Space ENvironment GEochemistry, and Ranging) MAG and FIPS instruments.

  13. Gingival plasma cell granuloma

    Directory of Open Access Journals (Sweden)

    Phadnaik Mangesh

    2010-01-01

    Full Text Available Plasma cell granuloma is a rare reactive lesion composed of polyclonal plasma cells. It manifests primarily in the lungs, but may occur in various other anatomic locations like the oral cavity. Intraoral plasma cell granulomas involving the tongue, lip, oral mucosa and gingiva have been reported in the past. This case presents a 54-year-old female with chronic periodontitis and mandibular anterior gingival overgrowth treated by Phase I therapy (scaling and root planing and excisional biopsy. Histological examination revealed inflammatory cell infiltrate containing sheets of plasma cells. Immunohistochemistry for kappa and lambda light chains showed a polyclonal staining pattern confirming a diagnosis of plasma cell granuloma. This case highlights the need to biopsy for unusual lesions to rule out potential neoplasms.

  14. Determination of the rotational population of H2 and D2 including high-N states in low temperature plasmas via the Fulcher-α transition

    Science.gov (United States)

    Briefi, S.; Rauner, D.; Fantz, U.

    2017-01-01

    Vibrational and rotational excitation of the hydrogen molecule can significantly affect molecular reaction rates in low pressure low temperature plasmas, for example for the creation of H- /D- ions via the dissociative attachment process. In general, the rotational population in these discharges is known to be non-thermal with an overpopulation of states with high rotational quantum number N. In contrast to a sophisticated direct measurement of the rotational distribution in the X g+1 Σ, v = 0 state, it is demonstrated that the determination can also be carried out up to high-N levels rather easily via optical emission spectroscopy utilizing the Fulcher-α transition of H2 and D2. The measured rotational populations can be described with a two-temperature distribution where the cold part reflects the population according to the gas temperature of the discharge. This has been verified by using the emission of the second positive system of nitrogen as independent gas temperature diagnostic. The hot part where the rotational temperature reaches several thousand Kelvin arises most probably from recombinative desorption of hydrogen at the discharge vessel wall where parts of the binding energy are converted into rotational excitation. Neglecting the hot population - what is often done when using the Fulcher-α transition as gas temperature diagnostic - can lead to a strong overestimation of Tgas. No fundamental differences in the rotational distributions between hydrogen and deuterium have been found, only the hot rotational temperature is smaller for D2 indicating an isotope-dependency of the recombinative desorption process.

  15. Electron vortex magnetic holes: A nonlinear coherent plasma structure

    Science.gov (United States)

    Haynes, Christopher T.; Burgess, David; Camporeale, Enrico; Sundberg, Torbjorn

    2015-01-01

    We report the properties of a novel type of sub-proton scale magnetic hole found in two dimensional particle-in-cell simulations of decaying turbulence with a guide field. The simulations were performed with a realistic value for ion to electron mass ratio. These structures, electron vortex magnetic holes (EVMHs), have circular cross-section. The magnetic field depression is associated with a diamagnetic azimuthal current provided by a population of trapped electrons in petal-like orbits. The trapped electron population provides a mean azimuthal velocity and since trapping preferentially selects high pitch angles, a perpendicular temperature anisotropy. The structures arise out of initial perturbations in the course of the turbulent evolution of the plasma, and are stable over at least 100 electron gyroperiods. We have verified the model for the EVMH by carrying out test particle and PIC simulations of isolated structures in a uniform plasma. It is found that (quasi-)stable structures can be formed provided that there is some initial perpendicular temperature anisotropy at the structure location. The properties of these structures (scale size, trapped population, etc.) are able to explain the observed properties of magnetic holes in the terrestrial plasma sheet. EVMHs may also contribute to turbulence properties, such as intermittency, at short scale lengths in other astrophysical plasmas.

  16. Electron vortex magnetic holes: A nonlinear coherent plasma structure

    Energy Technology Data Exchange (ETDEWEB)

    Haynes, Christopher T., E-mail: c.t.haynes@qmul.ac.uk; Burgess, David; Sundberg, Torbjorn [School of Physics and Astronomy, Queen Mary University of London, Mile End Road, London E1 4NS (United Kingdom); Camporeale, Enrico [Multiscale Dynamics, Centrum Wiskunde and Informatica (CWI), Amsterdam (Netherlands)

    2015-01-15

    We report the properties of a novel type of sub-proton scale magnetic hole found in two dimensional particle-in-cell simulations of decaying turbulence with a guide field. The simulations were performed with a realistic value for ion to electron mass ratio. These structures, electron vortex magnetic holes (EVMHs), have circular cross-section. The magnetic field depression is associated with a diamagnetic azimuthal current provided by a population of trapped electrons in petal-like orbits. The trapped electron population provides a mean azimuthal velocity and since trapping preferentially selects high pitch angles, a perpendicular temperature anisotropy. The structures arise out of initial perturbations in the course of the turbulent evolution of the plasma, and are stable over at least 100 electron gyroperiods. We have verified the model for the EVMH by carrying out test particle and PIC simulations of isolated structures in a uniform plasma. It is found that (quasi-)stable structures can be formed provided that there is some initial perpendicular temperature anisotropy at the structure location. The properties of these structures (scale size, trapped population, etc.) are able to explain the observed properties of magnetic holes in the terrestrial plasma sheet. EVMHs may also contribute to turbulence properties, such as intermittency, at short scale lengths in other astrophysical plasmas.

  17. A Catapult (Slingshot) Current Sheet Relaxation Model for Substorm Triggering

    Science.gov (United States)

    Machida, S.; Miyashita, Y.; Ieda, A.

    2010-12-01

    Based on the results of our superposed epoch analysis of Geotail data, we have proposed a catapult (slingshot) current sheet relaxation model in which earthward flows are produced in the central plasma sheet (CPS) due to the catapult (slingshot) current sheet relaxation, together with the rapid enhancement of Poynting flux toward the CPS in the lobe around X ~ -15 Re about 4 min before the substrom onset. These earthward flows are characterized by plasma pressure decrease and large amplitude magnetic field fluctuations. When these flows reach X ~ 12Re in the magnetotail, they give significant disturbances to the inner magnetosphere to initiate some instability such as a ballooning instability or other instabilities, and the substorm starts in the inner magnetosphere. The occurrence of the magnetic reconnection is a natural consequence of the initial convective earthward flows, because the relaxation of a highly stretched catapult current sheet produces a very thin current at its tailward edge being surrounded by intense magnetic fields which were formerly the off-equatorial lobe magnetic fields. Recently, Nishimura et al. [2010] reported that the substorm onset begins when faint poleward discrete arcs collide with equatorward quiet arcs. The region of earthward convective flows correlatively moves earthward prior to the onset. Thus, this region of the earthward convective flows seems to correspond to the faint poleward discrete arcs. Interestingly, our statistical analysis shows that the earthward convective flows are not produced by the magnetic reconnection, but they are attributed to the dominance of the earthward JxB force over the tailward pressure associated with the progress of the plasma sheet thinning.

  18. Number & operations task & drill sheets

    CERN Document Server

    Reed, Nat

    2011-01-01

    For grades 6-8, our State Standards-based combined resource meets the number & operations concepts addressed by the NCTM standards and encourages the students to review the concepts in unique ways. The task sheets introduce the mathematical concepts to the students around a central problem taken from real-life experiences, while the drill sheets provide warm-up and timed practice questions for the students to strengthen their procedural proficiency skills. Included are problems involving place value, fractions, addition, subtraction and using money. The combined task & drill sheets offer spac

  19. Seeing graphene-based sheets

    Directory of Open Access Journals (Sweden)

    Jaemyung Kim

    2010-03-01

    Full Text Available Graphene-based sheets such as graphene, graphene oxide and reduced graphene oxide have stimulated great interest due to their promising electronic, mechanical and thermal properties. Microscopy imaging is indispensable for characterizing these single atomic layers, and oftentimes is the first measure of sample quality. This review provides an overview of current imaging techniques for graphene-based sheets and highlights a recently developed fluorescence quenching microscopy technique that allows high-throughput, high-contrast imaging of graphene-based sheets on arbitrary substrate and even in solution.

  20. Perforation of metal sheets

    DEFF Research Database (Denmark)

    Steenstrup, Jens Erik

    The main purposes of this project are:1. Development of a dynamic model for the piercing and performation process2. Analyses of the main parameters3. Establishing demands for process improvements4. Expansion of the existing parameter limitsThe literature survey describes the process influence of ...... and a tool designed for punches with minimum length. Further, a systematic problem solving procedure is established. This procedure includes simulation as an integrated part, necessary for problem detection and to predict a favourable solution....... simulation is focused on the sheet deformation. However, the effect on the tool and press is included. The process model is based on the upper bound analysis in order to predict the force progress and hole characteristics etc. Parameter analyses are divided into two groups, simulation and experimental tests....... The tests complement each other in order to reveal the dominant parameters, which are decisive for the final product. Crucial demands are established to enable the desired improvements, focused on expanding the existing parameter limits. The demands include a justified need regarding a high-speed press...

  1. Common and Rare Alleles in Apolipoprotein B Contribute to Plasma Levels of LDL Cholesterol in the General Population

    DEFF Research Database (Denmark)

    Benn, M; Stene, MC; Nordestgaard, BG;

    2008-01-01

    CONTEXT: We have previously shown that rare mutations in the apolipoprotein B gene (APOB) may result in not only severe hypercholesterolemia and ischemic heart disease but also hypocholesterolemia. Despite this, common single-nucleotide polymorphisms (SNPs) in APOB have not convincingly been...... on cholesterol and apolipoprotein B levels. However, as predicted from the magnitude of the observed LDL cholesterol effects, none of these SNPs predicted risk of ischemic heart disease prospectively in the general population, in a case-control study, or as haplotypes. CONCLUSIONS: Multiple common and rare...... demonstrated to affect low-density lipoprotein (LDL) cholesterol levels. OBJECTIVE: We tested the hypothesis that nonsynonymous SNPs in three important functional domains of APOB and APOB tag SNPs predict levels of LDL cholesterol and apolipoprotein B and risk of ischemic heart disease. DESIGN...

  2. Plasma Free Amino Acid Profiles Predict Four-Year Risk of Developing Diabetes, Metabolic Syndrome, Dyslipidemia, and Hypertension in Japanese Population

    Science.gov (United States)

    Yamakado, Minoru; Nagao, Kenji; Imaizumi, Akira; Tani, Mizuki; Toda, Akiko; Tanaka, Takayuki; Jinzu, Hiroko; Miyano, Hiroshi; Yamamoto, Hiroshi; Daimon, Takashi; Horimoto, Katsuhisa; Ishizaka, Yuko

    2015-01-01

    Plasma free amino acid (PFAA) profile is highlighted in its association with visceral obesity and hyperinsulinemia, and future diabetes. Indeed PFAA profiling potentially can evaluate individuals’ future risks of developing lifestyle-related diseases, in addition to diabetes. However, few studies have been performed especially in Asian populations, about the optimal combination of PFAAs for evaluating health risks. We quantified PFAA levels in 3,701 Japanese subjects, and determined visceral fat area (VFA) and two-hour post-challenge insulin (Ins120 min) values in 865 and 1,160 subjects, respectively. Then, models between PFAA levels and the VFA or Ins120 min values were constructed by multiple linear regression analysis with variable selection. Finally, a cohort study of 2,984 subjects to examine capabilities of the obtained models for predicting four-year risk of developing new-onset lifestyle-related diseases was conducted. The correlation coefficients of the obtained PFAA models against VFA or Ins120 min were higher than single PFAA level. Our models work well for future risk prediction. Even after adjusting for commonly accepted multiple risk factors, these models can predict future development of diabetes, metabolic syndrome, and dyslipidemia. PFAA profiles confer independent and differing contributions to increasing the lifestyle-related disease risks in addition to the currently known factors in a general Japanese population. PMID:26156880

  3. Complex Dynamic Flows in Solar Flare Sheet Structures

    Science.gov (United States)

    McKenzie, David E.; Reeves, Katharine K.; Savage, Sabrina

    2012-01-01

    Observations of high-energy emission from solar flares often reveal the presence of large sheet-like structures, sometimes extending over a space comparable to the Sun's radius. Given that these structures are found between a departing coronal mass ejection and the post-eruption flare arcade, it is natural to associate the structure with a current sheet; though the relationship is unclear. Moreover, recent high-resolution observations have begun to reveal that the motions in this region are highly complex, including reconnection outflows, oscillations, and apparent wakes and eddies. We present a detailed first look at the complicated dynamics within this supra-arcade plasma, and consider implications for the interrelationship between the plasma and its embedded magnetic field.

  4. Generation of sheet currents by high frequency fast MHD waves

    Energy Technology Data Exchange (ETDEWEB)

    Núñez, Manuel, E-mail: mnjmhd@am.uva.es

    2016-07-01

    The evolution of fast magnetosonic waves of high frequency propagating into an axisymmetric equilibrium plasma is studied. By using the methods of weakly nonlinear geometrical optics, it is shown that the perturbation travels in the equatorial plane while satisfying a transport equation which enables us to predict the time and location of formation of shock waves. For plasmas of large magnetic Prandtl number, this would result into the creation of sheet currents which may give rise to magnetic reconnection and destruction of the original equilibrium. - Highlights: • Regular solutions of quasilinear hyperbolic systems may evolve into shocks. • The shock location is found for high frequency fast MHD waves. • The result is applied to static axisymmetric equilibria. • The previous process may lead to the formation of sheet currents and destruction of the equilibrium.

  5. Detection of thin current sheets and associated reconnection in the Earth's turbulent magnetosheath using cluster multi-point measurements

    Science.gov (United States)

    Chasapis, Alexandros; Retino, Alessandro; Sahraoui, Fouad; Greco, Antonella; Vaivads, Andris; Sundkvist, David; Canu, Patrick

    2013-04-01

    Magnetic reconnection occurs in turbulent plasma within a large number of volume-filling thin current sheets and is one major candidate for energy dissipation of turbulent plasma. Such dissipation results in particle heating and non-thermal particle acceleration. In situ observations are needed to study the detailed properties of thin current sheets and associated reconnection, in order to determine its importance as a dissipation mechanism at small scales. In particular, multi-point measurements are crucial to unambiguously identify spatial scales (e.g current sheet thickness) and estimate key quantities such as E*J. Here we present a study of the properties of thin current sheets detected in the Earths magnetosheath downstream of the quasi-parallel shock by using Cluster spacecraft data. The current sheets were detected by the rotation of the magnetic field as computed by four-point measurements. We study the distribution of current sheets as a function of the magnetic shear angle θ, their duration and the waiting time between consecutive current sheets. We found that high shear (θ > 90 degrees) current sheets show different properties with respect to low shear current sheets (θ < 90 degrees). These high-shear current sheets account for about ˜ 20% of the total and have an average thickness comparable to the ion inertial length. We also compare our four-point detection method with other single-point methods (e.g. Partial Variance of Increments - PVI) and we discuss the results of such comparison.

  6. Plasma triglycerides, an independent predictor of cardiovascular disease in men: a prospective study based on a population with prevalent metabolic syndrome.

    Science.gov (United States)

    Onat, Altan; Sari, Ibrahim; Yazici, Mehmet; Can, Günay; Hergenç, Gülay; Avci, Günsel S

    2006-03-22

    We aimed to assess whether fasting plasma triglycerides independently predicted future fatal and nonfatal cardiovascular disease (CVD) in a population having a high prevalence of the metabolic syndrome. In the Turkish Adult Risk Factor Study, a population-based survey, 2682 men and women 20 years of age or over with fasting triglyceride values available and free of CVD at baseline examination in 1990, were prospectively followed up till 2003/04. Triglyceride concentrations were measured by the enzymatic dry chemistry method and stratified into sex-specific quintiles. Information on the mode of death was obtained from first-degree relatives and/or health personnel of local health office. Diagnosis of coronary heart disease and stroke among survivors was based on history, physical examination of the cardiovascular system and Minnesota coding of resting electrocardiograms. A total of 120 fatal and 221 new nonfatal CVD occurred among adults (mean age 43+/-14) during a mean 9.3 years of follow-up. CVD was significantly and independently predicted by the top versus the bottom fasting triglyceride quintile in logistic regression analyses when adjusted for age, sex, BMI, systolic blood pressure, total cholesterol, lipid-lowering medication, status of smoking and of glucose regulation (relative risk [RR] in men and all adults 2.38 and 1.79, respectively, p both triglycerides are predictive of future CVD among men with an HR of 1.4, independent of age, diabetes, lipid-lowering medication, traditional risk factors including total cholesterol or HDL-C, in a population in which metabolic syndrome prevails. A modest independent risk increment in women did not reach significance.

  7. State Fact Sheets on COPD

    Science.gov (United States)

    ... Submit Search The CDC Chronic Obstructive Pulmonary Disease (COPD) Note: Javascript is disabled or is not supported ... message, please visit this page: About CDC.gov . COPD Homepage Data and Statistics Fact Sheets Publications Publications ...

  8. Palaeoclimate science: Pulsating ice sheet

    Science.gov (United States)

    Vieli, Andreas

    2017-02-01

    During the last ice age, huge numbers of icebergs were episodically discharged from an ice sheet that covered North America. Numerical modelling suggests that these events resulted from a conceptually simple feedback cycle. See Letter p.332

  9. Crescent Lake Wilderness Reference Sheet

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Reference sheet includes information about Crescent Lake National Wildlife Refuge, and results of the public hearing for Crescent Lake Wilderness Proposal.

  10. Industrial Stormwater Fact Sheet Series

    Science.gov (United States)

    Fact sheets for the industrial sectors regulated by the MSGP. Each describes the types of facilities included in the sector, typical pollutants associated with the sector, and types of stormwater control measures used to minimize pollutant discharge.

  11. 2008 Swimming Season Fact Sheets

    Science.gov (United States)

    To help beachgoers make informed decisions about swimming at U.S. beaches, EPA annually publishes state-by-state data about beach closings and advisories for the previous year's swimming season. These fact sheets summarize that information by state.

  12. 2007 Swimming Season Fact Sheets

    Science.gov (United States)

    To help beachgoers make informed decisions about swimming at U.S. beaches, EPA annually publishes state-by-state data about beach closings and advisories for the previous year's swimming season. These fact sheets summarize that information by state.

  13. 2006 Swimming Season Fact Sheets

    Science.gov (United States)

    To help beachgoers make informed decisions about swimming at U.S. beaches, EPA annually publishes state-by-state data about beach closings and advisories for the previous year's swimming season. These fact sheets summarize that information by state.

  14. 2009 Swimming Season Fact Sheets

    Science.gov (United States)

    To help beachgoers make informed decisions about swimming at U.S. beaches, EPA annually publishes state-by-state data about beach closings and advisories for the previous year's swimming season. These fact sheets summarize that information by state.

  15. 2010 Swimming Season Fact Sheets

    Science.gov (United States)

    To help beachgoers make informed decisions about swimming at U.S. beaches, EPA annually publishes state-by-state data about beach closings and advisories for the previous year's swimming season. These fact sheets summarize that information by state.

  16. Effects of Canarium odontophyllum leaves on plasma glucose and T lymphocyte population in streptozotocin-induced diabetic rats.

    Science.gov (United States)

    Saari, Shafikha Mohd; Basri, Dayang Fredalina; Budin, Siti Balkis; Warif, Nor Malia Abd

    2017-02-01

    Type 1 diabetes mellitus is a chronic disease characterized by lack of insulin production. Immune mechanisms are implicated in the pathogenesis of Type 1 diabetes. Canarium odontophyllum (CO) fruits and leaves have been shown to possess high antioxidant activity. This study was conducted to evaluate the effects of CO leaves aqueous extract on the blood glucose and T lymphocyte population in the spleen of streptozotocin (STZ)-induced diabetic rats. Nineteen male Sprague-Dawley rats were randomly divided into three groups: normal, diabetic control and CO treated diabetic groups. Diabetes was induced by a single intraperitoneal injection of 65 mg STZ/kg body weight. The extract of CO leaves was administered orally by force feeding daily at the dose of 300 mg/kg for 28 days. The rats were sacrificed at the end of the study and the spleen was harvested for flow cytometry analysis. The results showed a significant decrease in body weight of diabetic and CO treated diabetic groups compared with the normal group (p diabetic group was significantly lower than the diabetic group (p Diabetic and CO treated diabetic groups showed a significant increase in the percentage of spleen CD3(+) CD4(+) T lymphocytes (p diabetic rats.

  17. Common and Rare Alleles in Apolipoprotein B Contribute to Plasma Levels of LDL Cholesterol in the General Population

    DEFF Research Database (Denmark)

    Benn, M; Stene, MC; Nordestgaard, BG;

    2008-01-01

    demonstrated to affect low-density lipoprotein (LDL) cholesterol levels. OBJECTIVE: We tested the hypothesis that nonsynonymous SNPs in three important functional domains of APOB and APOB tag SNPs predict levels of LDL cholesterol and apolipoprotein B and risk of ischemic heart disease. DESIGN......: This was a prospective study with 25 yr 100% follow up, The Copenhagen City Heart Study. SETTING: The study was conducted in the Danish general population. PARTICIPANTS: Participants included 9185 women and men aged 20-80+ yr. MAIN OUTCOME MEASURES: Levels of LDL cholesterol and apolipoprotein B and risk of ischemic......Q (0.09), E4154K (0.17), and N4311S (0.21). SNPs were associated with increases (T71I, Ivs181708g>t, T2488Tc>t, R3611) or decreases (Ivs4+171c>a, A591V, Ivs18+379a>c, P2712L, E4154, N4311S) in LDL cholesterol from -4.7 to +8.2% (-0.28 to 0.30 mmol/liter; P

  18. Energy information sheets, July 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-07-01

    The National Energy Information Center (NEIC), as part of its mission, provides energy information and referral assistance to Federal, State, and local governments, the academic community, business and industrial organizations, and the public. The Energy Information Sheets was developed to provide general information on various aspects of fuel production, prices, consumption, and capability. Additional information on related subject matter can be found in other Energy Information Administration (EIA) publications as referenced at the end of each sheet.

  19. Energy information sheets, September 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-09-01

    The National Energy Information Center (NEIC), as part of its mission, provides energy information and referral assistance to Federal, State, and local governments, the academic community, business and industrial organizations, and the public. The Energy Information Sheets was developed to provide general information on various aspects of fuel production, prices, consumption, and capability. Additional information on related subject matter can be found in other Energy Information Administration (EIA) publications as referenced at the end of each sheet.

  20. The 2013 social balance sheet

    OpenAIRE

    Pierrette Heuse

    2014-01-01

    The transposition into national law of Directive 2013/34/EU on the annual financial statements of companies, expected by no later than July 2015, could alter the statistical obligations on small firms in connection with the filing of their annual accounts. In any case, the social balance sheet can no longer form an integral part of their accounts. Nevertheless, it contains original information whose usefulness is highlighted, on the basis of the social balance sheets for 2012, by examining th...

  1. Plasma Carotenoids, Tocopherols, and Retinol in the Age-Stratified (35–74 Years) General Population: A Cross-Sectional Study in Six European Countries

    Science.gov (United States)

    Stuetz, Wolfgang; Weber, Daniela; Dollé, Martijn E. T.; Jansen, Eugène; Grubeck-Loebenstein, Beatrix; Fiegl, Simone; Toussaint, Olivier; Bernhardt, Juergen; Gonos, Efstathios S.; Franceschi, Claudio; Sikora, Ewa; Moreno-Villanueva, María; Breusing, Nicolle; Grune, Tilman; Bürkle, Alexander

    2016-01-01

    Blood micronutrient status may change with age. We analyzed plasma carotenoids, α-/γ-tocopherol, and retinol and their associations with age, demographic characteristics, and dietary habits (assessed by a short food frequency questionnaire) in a cross-sectional study of 2118 women and men (age-stratified from 35 to 74 years) of the general population from six European countries. Higher age was associated with lower lycopene and α-/β-carotene and higher β-cryptoxanthin, lutein, zeaxanthin, α-/γ-tocopherol, and retinol levels. Significant correlations with age were observed for lycopene (r = −0.248), α-tocopherol (r = 0.208), α-carotene (r = −0.112), and β-cryptoxanthin (r = 0.125; all p < 0.001). Age was inversely associated with lycopene (−6.5% per five-year age increase) and this association remained in the multiple regression model with the significant predictors (covariables) being country, season, cholesterol, gender, smoking status, body mass index (BMI (kg/m2)), and dietary habits. The positive association of α-tocopherol with age remained when all covariates including cholesterol and use of vitamin supplements were included (1.7% vs. 2.4% per five-year age increase). The association of higher β-cryptoxanthin with higher age was no longer statistically significant after adjustment for fruit consumption, whereas the inverse association of α-carotene with age remained in the fully adjusted multivariable model (−4.8% vs. −3.8% per five-year age increase). We conclude from our study that age is an independent predictor of plasma lycopene, α-tocopherol, and α-carotene. PMID:27706032

  2. Estimating the future ice sheet hydropower potential in Paakitsoq, Ilulissat, West Greenland

    DEFF Research Database (Denmark)

    Ahlstrøm, Andreas P.; Mottram, R.H.; Nielsen, C.

    2008-01-01

    long-term investment for an Arctic community of modest population. Here we present a new bedrock and surface map of the Paakitsoq/Swiss Camp part of the Greenland ice sheet and a prediction of the future discharge up to 2080 AD using regional climate model output, dynamic ice sheet modelling......Meltwater running off the Greenland ice sheet yield significant hydropower potentials in catchments bordering the ice sheet, especially in West and South Greenland. Hydropower has been chosen as the most desired source of energy by the Greenland Home Rule, but recent changes in the Greenland ice...... sheet has emphasized the risk of sudden changes in catchment supply. In this study, we present a thorough investigation of hydropower feasibility at the Paakitsoq basin, near Ilulissat in West Greenland. The catchment is completely dominated by the Greenland ice sheet which provides large quantities...

  3. Photoacoustic microscopy of myocardial sheet architecture in unfixed and unstained mammalian hearts

    Science.gov (United States)

    Zhang, Chi; Cheng, Ya-Jian; Yao, Da-Kang; Wickline, Samuel; Wang, Lihong V.

    2012-02-01

    The laminar myocardial sheet architecture and its dynamic change play a key role in myocardial wall thickening. Histology, confocal optical microscopy (COM), and diffusion tensor MRI (DTI) have been used to unveil the structures and functions of the myocardial sheets. However, histology and COM require fixation, sectioning, and staining processes, which dehydrate and deform the sheet architecture. Although DTI can delineate sheet architecture nondestructively in viable hearts, it cannot provide cellular-level resolution. Here we show that photoacoustic microscopy (PAM), with high resolution (~1 μm) and label-free detection, is appropriate for imaging 3D myocardial architecture. Perfused half-split mouse hearts were also imaged by PAM in vitro without fixation, dehydration, nor staining. The laminar myocardial sheet architecture was clearly visualized within a 0.15 mm depth range. Two populations of oppositely signed sheet angles were observed. Therefore, PAM promises to access dynamic changes of myocardial architectures in ex vivo perfused-viable hearts.

  4. Cyclic modular beta-sheets.

    Science.gov (United States)

    Woods, R Jeremy; Brower, Justin O; Castellanos, Elena; Hashemzadeh, Mehrnoosh; Khakshoor, Omid; Russu, Wade A; Nowick, James S

    2007-03-07

    The development of peptide beta-hairpins is problematic, because folding depends on the amino acid sequence and changes to the sequence can significantly decrease folding. Robust beta-hairpins that can tolerate such changes are attractive tools for studying interactions involving protein beta-sheets and developing inhibitors of these interactions. This paper introduces a new class of peptide models of protein beta-sheets that addresses the problem of separating folding from the sequence. These model beta-sheets are macrocyclic peptides that fold in water to present a pentapeptide beta-strand along one edge; the other edge contains the tripeptide beta-strand mimic Hao [JACS 2000, 122, 7654] and two additional amino acids. The pentapeptide and Hao-containing peptide strands are connected by two delta-linked ornithine (deltaOrn) turns [JACS 2003, 125, 876]. Each deltaOrn turn contains a free alpha-amino group that permits the linking of individual modules to form divalent beta-sheets. These "cyclic modular beta-sheets" are synthesized by standard solid-phase peptide synthesis of a linear precursor followed by solution-phase cyclization. Eight cyclic modular beta-sheets 1a-1h containing sequences based on beta-amyloid and macrophage inflammatory protein 2 were synthesized and characterized by 1H NMR. Linked cyclic modular beta-sheet 2, which contains two modules of 1b, was also synthesized and characterized. 1H NMR studies show downfield alpha-proton chemical shifts, deltaOrn delta-proton magnetic anisotropy, and NOE cross-peaks that establish all compounds but 1c and 1g to be moderately or well folded into a conformation that resembles a beta-sheet. Pulsed-field gradient NMR diffusion experiments show little or no self-association at low (

  5. A Tailward Moving Current Sheet Normal Magnetic Field Front Followed by an Earthward Moving Dipolarization Front

    Science.gov (United States)

    Hwang, K.-J.; Goldstein, M. L.; Moore, T. E.; Walsh, B. M.; Baishev, D. G.; Moiseyev, A. V.; Shevtsov, B. M.; Yumoto, K.

    2014-01-01

    A case study is presented using measurements from the Cluster spacecraft and ground-based magnetometers that show a substorm onset propagating from the inner to outer plasma sheet. On 3 October 2005, Cluster, traversing an ion-scale current sheet at the near-Earth plasma sheet, detected a sudden enhancement of Bz, which was immediately followed by a series of flux rope structures. Both the local Bz enhancement and flux ropes propagated tailward. Approximately 5 min later, another Bz enhancement, followed by a large density decrease, was observed to rapidly propagate earthward. Between the two Bz enhancements, a significant removal of magnetic flux occurred, possibly resulting from the tailward moving Bz enhancement and flux ropes. In our scenario, this flux removal caused the magnetotail to be globally stretched so that the thinnest sheet formed tailward of Cluster. The thinned current sheet facilitated magnetic reconnection that quickly evolved from plasma sheet to lobe and generated the later earthward moving dipolarization front (DF) followed by a reduction in density and entropy. Ground magnetograms located near the meridian of Cluster's magnetic foot points show two-step bay enhancements. The positive bay associated with the first Bz enhancement indicates that the substorm onset signatures propagated from the inner to the outer plasma sheet, consistent with the Cluster observation. The more intense bay features associated with the later DF are consistent with the earthward motion of the front. The event suggests that current disruption signatures that originated in the near-Earth current sheet propagated tailward, triggering or facilitating midtail reconnection, thereby preconditioning the magnetosphere for a later strong substorm enhancement.

  6. Mercury's Magnetospheric Cusps and Cross-Tail Current Sheet: Structure and Dynamics

    Science.gov (United States)

    Poh, Gang Kai

    Mercury has proven to be a unique natural laboratory for space plasma processes. Mercury's magnetosphere is formed by the interaction between its intrinsic planetary magnetic field and the supersonic solar wind. The structure of Mercury's magnetosphere is very similar to Earth's; yet the results from the MESSENGER mission to Mercury have shown that the spatial and temporal scales of magnetospheric processes are very different at Mercury. In this thesis, we analyze in situ observations from the MESSENGER spacecraft to characterize and understand the dynamic physical plasma processes occurring in Mercury's magnetosphere. We identified and analyzed 345 plasma filaments in Mercury's northern magnetospheric cusp to determine their physical properties. Cusp plasma filaments are magnetic structures that are identified on the basis of their characteristic 2-3 seconds long decrease in magnetic field intensity. Our analysis indicates that these cusp filaments are cylindrical flux tubes filled with plasma, which causes a diamagnetic decrease in the magnetic field inside the flux tube. MESSENGER observations of flux transfer events (FTEs) and cusp filament suggests that cusp filaments properties are the low-altitude extension of FTEs formed at Mercury's dayside magnetopause. We examined 319 central plasma sheet crossings observed by MESSENGER. Using a Harris model, we determined the physical properties of Mercury's cross-tail current sheet. Analysis of BZ in the current sheet indicated that MESSENGER usually crossed the current sheet sunward of the Near Mercury Neutral Line. Magnetohydrodynamics-based analysis using the MESSENGER magnetic field and plasma measurements suggests that heavy planetary ions and/or ion temperature anisotropy may be important in maintaining radial stress balance within Mercury's central plasma sheet. We report the observation of significant dawn-dusk variation in Mercury's cross-tail current sheet with thicker, lower plasma beta dawn side current

  7. Horizontal electromagnetic casting of thin metal sheets

    Energy Technology Data Exchange (ETDEWEB)

    Hull, John R. (Hinsdale, IL); Lari, Robert J. (Aurora, IL); Praeg, Walter F. (Palos Park, IL); Turner, Larry R. (Naperville, IL)

    1988-01-01

    Thin metal sheets are cast by magnetically suspending molten metal deposited within a ferromagnetic yoke and between AC conducting coils and linearly displacing the magnetically levitated liquid metal while it is being cooled to form a solid metal sheet. Magnetic flux increases as the molten metal sheet moves downward and decreases as the molten metal sheet moves upward to stabilize the sheet and maintain it in equilibrium as it is linearly displaced and solidified by cooling gases. A conducting shield is electrically coupled to the molten metal sheet by means of either metal sheet engaging rollers or brushes on the solidified metal, and by means of an electrode in the vessel containing the molten metal thereby providing a return path for the eddy currents induced in the metal sheet by the AC coil generated magnetic flux. Variation in the geometry of the conducting shield allows the magnetic flux between the metal sheet and the conducting shield to be varied and the thickness in surface quality of the metal sheet to be controlled. Side guards provide lateral containment for the molten metal sheet and stabilize and shape the magnetic field while a leader sheet having electromagnetic characteristics similar to those of the metal sheet is used to start the casting process and precedes the molten metal sheet through the magnet and forms a continuous sheet therewith. The magnet may be either U-shaped with a single racetrack coil or may be rectangular with a pair of facing bedstead coils.

  8. Horizontal electromagnetic casting of thin metal sheets

    Energy Technology Data Exchange (ETDEWEB)

    Hull, John R. (Hinsdale, IL); Lari, Robert J. (Aurora, IL); Praeg, Walter F. (Palos Park, IL); Turner, Larry R. (Naperville, IL)

    1987-01-01

    Thin metal sheets are cast by magnetically suspending molten metal deposited within a ferromagnetic yoke and between AC conducting coils and linearly displacing the magnetically levitated liquid metal while it is being cooled to form a solid metal sheet. Magnetic flux increases as the molten metal sheet moves downward and decreases as the molten metal sheet moves upward to stabilize the sheet and maintain it in equilibrium as it is linearly displaced and solidified by cooling gases. A conducting shield is electrically coupled to the molten metal sheet by means of either metal sheet engaging rollers or brushes on the solidified metal, and by means of an electrode in the vessel containing the molten metal thereby providing a return path for the eddy currents induced in the metal sheet by the AC coil generated magnetic flux. Variation in the geometry of the conducting shield allows the magnetic flux between the metal sheet and the conducting shield to be varied and the thickness in surface quality of the metal sheet to be controlled. Side guards provide lateral containment for the molten metal sheet and stabilize and shape the magnetic field while a leader sheet having electromagnetic characteristics similar to those of the metal sheet is used to start the casting process and precedes the molten metal sheet through the magnet and forms a continuous sheet therewith. The magnet may be either U-shaped with a single racetrack coil or may be rectangular with a pair of facing bedstead coils.

  9. Dynamo-driven plasmoid formation from a current-sheet instability

    Science.gov (United States)

    Ebrahimi, F.

    2016-12-01

    Axisymmetric current-carrying plasmoids are formed in the presence of nonaxisymmetric fluctuations during nonlinear three-dimensional resistive MHD simulations in a global toroidal geometry. We utilize the helicity injection technique to form an initial poloidal flux in the presence of a toroidal guide field. As helicity is injected, two types of current sheets are formed from (1) the oppositely directed field lines in the injector region (primary reconnecting current sheet), and (2) the poloidal flux compression near the plasma edge (edge current sheet). We first find that nonaxisymmetric fluctuations arising from the current-sheet instability isolated near the plasma edge have tearing parity but can nevertheless grow fast (on the poloidal Alfven time scale). These modes saturate by breaking up the current sheet. Second, for the first time, a dynamo poloidal flux amplification is observed at the reconnection site (in the region of the oppositely directed magnetic field). This fluctuation-induced flux amplification increases the local Lundquist number, which then triggers a plasmoid instability and breaks the primary current sheet at the reconnection site. The plasmoids formation driven by large-scale flux amplification, i.e., a large-scale dynamo, observed here has strong implications for astrophysical reconnection as well as fast reconnection events in laboratory plasmas.

  10. Automobile sheet metal part production with incremental sheet forming

    Directory of Open Access Journals (Sweden)

    İsmail DURGUN

    2016-02-01

    Full Text Available Nowadays, effect of global warming is increasing drastically so it leads to increased interest on energy efficiency and sustainable production methods. As a result of adverse conditions, national and international project platforms, OEMs (Original Equipment Manufacturers, SMEs (Small and Mid-size Manufacturers perform many studies or improve existing methodologies in scope of advanced manufacturing techniques. In this study, advanced manufacturing and sustainable production method "Incremental Sheet Metal Forming (ISF" was used for sheet metal forming process. A vehicle fender was manufactured with or without die by using different toolpath strategies and die sets. At the end of the study, Results have been investigated under the influence of method and parameters used.Keywords: Template incremental sheet metal, Metal forming

  11. Optimal swimming of a sheet.

    Science.gov (United States)

    Montenegro-Johnson, Thomas D; Lauga, Eric

    2014-06-01

    Propulsion at microscopic scales is often achieved through propagating traveling waves along hairlike organelles called flagella. Taylor's two-dimensional swimming sheet model is frequently used to provide insight into problems of flagellar propulsion. We derive numerically the large-amplitude wave form of the two-dimensional swimming sheet that yields optimum hydrodynamic efficiency: the ratio of the squared swimming speed to the rate-of-working of the sheet against the fluid. Using the boundary element method, we show that the optimal wave form is a front-back symmetric regularized cusp that is 25% more efficient than the optimal sine wave. This optimal two-dimensional shape is smooth, qualitatively different from the kinked form of Lighthill's optimal three-dimensional flagellum, not predicted by small-amplitude theory, and different from the smooth circular-arc-like shape of active elastic filaments.

  12. Counter-facing plasma focus system as a repetitive and/or long-pulse high energy density plasma source

    Science.gov (United States)

    Aoyama, Yutaka; Nakajima, Mitsuo; Horioka, Kazuhiko

    2009-11-01

    A plasma focus system composed of a pair of counter-facing coaxial plasma guns is proposed as a long-pulse and/or repetitive high energy density plasma source. A proof-of-concept experiment demonstrated that with an assist of breakdown and outer electrode connections, current sheets evolved into a configuration for stable plasma confinement at the center of the electrodes. The current sheets could successively compress and confine the high energy density plasma every half period of the discharge current, enabling highly repetitive light emissions in extreme ultraviolet region with time durations in at least ten microseconds.

  13. Sheet Bending using Soft Tools

    Science.gov (United States)

    Sinke, J.

    2011-05-01

    Sheet bending is usually performed by air bending and V-die bending processes. Both processes apply rigid tools. These solid tools facilitate the generation of software for the numerical control of those processes. When the lower rigid die is replaced with a soft or rubber tool, the numerical control becomes much more difficult, since the soft tool deforms too. Compared to other bending processes the rubber backed bending process has some distinct advantages, like large radius-to-thickness ratios, applicability to materials with topcoats, well defined radii, and the feasibility of forming details (ridges, beads). These advantages may give the process exclusive benefits over conventional bending processes, not only for industries related to mechanical engineering and sheet metal forming, but also for other disciplines like Architecture and Industrial Design The largest disadvantage is that also the soft (rubber) tool deforms. Although the tool deformation is elastic and recovers after each process cycle, the applied force during bending is related to the deformation of the metal sheet and the deformation of the rubber. The deformation of the rubber interacts with the process but also with sheet parameters. This makes the numerical control of the process much more complicated. This paper presents a model for the bending of sheet materials using a rubber lower die. This model can be implemented in software in order to control the bending process numerically. The model itself is based on numerical and experimental research. In this research a number of variables related to the tooling and the material have been evaluated. The numerical part of the research was used to investigate the influence of the features of the soft lower tool, like the hardness and dimensions, and the influence of the sheet thickness, which also interacts with the soft tool deformation. The experimental research was focused on the relation between the machine control parameters and the most

  14. Heliospheric current sheet and its interaction with solar cosmic rays

    Science.gov (United States)

    Malova, Helmi; Popov, Victor; Grigorenko, Elena; Dunko, Andrey; Petrukovich, Anatoly

    2016-04-01

    We investigated effects resulting from the interaction of solar cosmic rays (SCR) with the heliospheric current sheet (HCS) in the solar wind. Self-consistent kinetic model of the HCS is developed, where ions demonstrate quasi-adiabatic dynamics. HCS is considered as the equilibrium embedded current structure, where the two main kinds of plasma with different temperatures give the main contribution to the current (low-energy background plasma and SCR). It is shown that HCS is a relatively thin multiscale configuration of the current sheet, embedded in a thicker plasma layer. The taking into account of SCR particles in HCS could lead to a change of its structure and to enhancement of its properties such as the embedding and multi-scaling. Parametric family of solutions is considered where the current balance in HCS is provided at different temperatures of SCR and different concentrations of high-energy plasma. Concentrations of SCR are determined which may contribute to the thickening of the HCS that can be observed in satellite studies. The possibility to apply this modeling for the explanation of experimental observations is considered.

  15. Ice sheet hydrology - a review

    Energy Technology Data Exchange (ETDEWEB)

    Jansson, Peter; Naeslund, Jens-Ove [Dept. of Physical Geography and Quaternary Geology, Stockholm Univ., Stockholm (Sweden); Rodhe, Lars [Geological Survey of Sweden, Uppsala (Sweden)

    2007-03-15

    This report summarizes the theoretical knowledge on water flow in and beneath glaciers and ice sheets and how these theories are applied in models to simulate the hydrology of ice sheets. The purpose is to present the state of knowledge and, perhaps more importantly, identify the gaps in our understanding of ice sheet hydrology. Many general concepts in hydrology and hydraulics are applicable to water flow in glaciers. However, the unique situation of having the liquid phase flowing in conduits of the solid phase of the same material, water, is not a commonly occurring phenomena. This situation means that the heat exchange between the phases and the resulting phase changes also have to be accounted for in the analysis. The fact that the solidus in the pressure-temperature dependent phase diagram of water has a negative slope provides further complications. Ice can thus melt or freeze from both temperature and pressure variations or variations in both. In order to provide details of the current understanding of water flow in conjunction with deforming ice and to provide understanding for the development of ideas and models, emphasis has been put on the mathematical treatments, which are reproduced in detail. Qualitative results corroborating theory or, perhaps more often, questioning the simplifications made in theory, are also given. The overarching problem with our knowledge of glacier hydrology is the gap between the local theories of processes and the general flow of water in glaciers and ice sheets. Water is often channelized in non-stationary conduits through the ice, features which due to their minute size relative to the size of glaciers and ice sheets are difficult to incorporate in spatially larger models. Since the dynamic response of ice sheets to global warming is becoming a key issue in, e.g. sea-level change studies, the problems of the coupling between the hydrology of an ice sheet and its dynamics is steadily gaining interest. New work is emerging

  16. Spontaneous current sheets in magnetic fields with applications to stellar X-rays

    CERN Document Server

    Parker, Eugene N

    1994-01-01

    Expanding upon the ideas first proposed in his seminal book Cosmical Magnetic Fields, Eugene N. Parker here offers the first in-depth treatment of the magnetohydrodynamic theory of spontaneous magnetic discontinuities. In detailing his theory of the spontaneous formation of tangential discontinuities (current sheets) in a magnetic field embedded in highly conducting plasma, Parker shows how it can be used to explain the activity of the external magnetic fields of planets, stars, interstellar gas clouds, and galaxies, as well as the magnetic fields in laboratory plasmas. Provocative and fascinating, Spontaneous Current Sheets in Magnetic Fields presents a bold new theory that will excite interest and discussion throughout the space physics community.

  17. The Earth's Electron Radiation Belts Modeling: from the Source Population to Relativistic Energies

    Science.gov (United States)

    Aseev, N.; Shprits, Y. Y.; Kellerman, A. C.; Drozdov, A.; Zhu, H.

    2016-12-01

    The dynamics of the Earth's electron radiation belts is characterized by intricate interactions of different particle populations. During the main phase of a geomagnetic storm, electron source (tens keV) and seed (hundreds keV) populations are injected from the plasma sheet to the outer belt region. The source population transfers energy to electromagnetic waves, while the seed population can be accelerated locally by interaction with chorus waves. Electrons can also be lost by scattering into the loss cone due to wave-particle interaction and by magnetopause shadowing due to outward radial motion. In this work, we present results of simulations of the dynamics of electron fluxes in the inner magnetosphere from a few keV to relativistic energies of several MeV using the VERB-4D code. The code includes radial, energy and pitch angle diffusion, convection and adiabatic effects due to compression or expansion of the magnetic field. We extended the spatial outer boundary of the computational domain to 10-15 RE which allow us to study, how the source and seed population particles are convected from the plasma sheet, accelerated to relativistic energies and lost to the atmosphere or the magnetopause. The results of simulations reproduce Van Allen Probes, GOES and THEMIS observations, indicating that magnetospheric convection is the main driver of electron dynamics above the GEO, while radial diffusion and local diffusion are the most important processes in the outer belt region.

  18. Plasma physics abstracts, 1 January - 31 December, 1986

    Science.gov (United States)

    Gurnett, D. A.; Dangelo, N.; Goertz, C. K.

    1987-01-01

    Topics addressed include: ion-cyclotron waves; plasma waves; solar wind lithium releases; bow shock; Pi2 wave bursts; auroral kilometric radiation; ion energization; magnetic field corrections; electric fields; magnetospheric processes; electron acceleration; inner heliosphere; nightside auroral zone; computerized simulation; plasma wave turbulence; and magnetohydrodynamic waves in plasma sheets.

  19. Residual stress in plasma-sprayed ceramic turbine tip and gas-path seal specimens

    Science.gov (United States)

    Hendricks, R. C.; Mcdonald, G.; Mullen, R. L.

    1983-01-01

    The residual stresses in a ceramic sheet material used for turbine blade tip gas path seals, were estimated. These stresses result from the plasma spraying process which leaves the surface of the sheet in tension. To determine the properties of plasma sprayed ZrO2-Y2O3 sheet material, its load deflection characteristics were measured. Estimates of the mechanical properties for sheet materials were found to differ from those reported for plasma sprayed bulk materials. Previously announced in STAR as N83-28380

  20. Exploring reconnection, current sheets, and dissipation in a laboratory MHD turbulence experiment

    Science.gov (United States)

    Schaffner, D. A.

    2015-12-01

    The Swarthmore Spheromak Experiment (SSX) can serve as a testbed for studying MHD turbulence in a controllable laboratory setting, and in particular, explore the phenomena of reconnection, current sheets and dissipation in MHD turbulence. Plasma with turbulently fluctuating magnetic and velocity fields can be generated using a plasma gun source and launched into a flux-conserving cylindrical tunnel. No background magnetic field is applied so internal fields are allowed to evolve dynamically. Point measurements of magnetic and velocity fluctuations yield broadband power-law spectra with a steepening breakpoint indicative of the onset of a dissipation scale. The frequency range at which this steepening occurs can be correlated to the ion inertial scale of the plasma, a length which is characteristic of the size of current sheets in MHD plasmas and suggests a connection to dissipation. Observation of non-Gaussian intermittent jumps in magnetic field magnitude and angle along with measurements of ion temperature bursts suggests the presence of current sheets embedded within the turbulent plasma, and possibly even active reconnection sites. Additionally, structure function analysis coupled with appeals to fractal scaling models support the hypothesis that current sheets are associated with dissipation in this system.

  1. Microchemistry in aluminium sheet production

    NARCIS (Netherlands)

    Lok, Z.J.

    2005-01-01

    The production of aluminium sheet alloys from as-cast ingots is a complex process, involving several rolling operations in combination with various thermal heat treatments. Through their influence on the alloy microchemistry and microstructure, these thermomechanical treatments are all aimed at cont

  2. Learning from Balance Sheet Visualization

    Science.gov (United States)

    Tanlamai, Uthai; Soongswang, Oranuj

    2011-01-01

    This exploratory study examines alternative visuals and their effect on the level of learning of balance sheet users. Executive and regular classes of graduate students majoring in information technology in business were asked to evaluate the extent of acceptance and enhanced capability of these alternative visuals toward their learning…

  3. Sports Injury Prevention Tip Sheet

    Science.gov (United States)

    ... Commemorative Giving Employment at AAP Advertise with AAP Advertising on AAP.org Advertising on AAP Journals & Publications AAP Mailing and eMail ... Help/Feedback a a a print email share Facebook Twitter 2017 Sports Injury Prevention Tip Sheet 3/ ...

  4. Application of Incremental Sheet Forming

    Directory of Open Access Journals (Sweden)

    Karbowski Krzysztof

    2015-12-01

    Full Text Available This paper describes some manufacturing aspects and an example of application of the Incremental Sheet Forming (ISF technology which was used for production of the craniofacial prosthesis. The brief description of prosthesis designing was presented as well. The main topic of the paper is comparison of milling and ISF technologies for preparing the tools for prosthesis thermoforming.

  5. High Blood Pressure Fact Sheet

    Science.gov (United States)

    ... High Blood Pressure Salt Cholesterol Million Hearts® WISEWOMAN High Blood Pressure Fact Sheet Language: English Español (Spanish) Recommend on ... time. High blood pressure is also called hypertension. High Blood Pressure in the United States Having high blood pressure ...

  6. Fact Sheets on Institutional Racism.

    Science.gov (United States)

    Foundation for Change, Inc., New York, NY.

    This fact sheet on institutional racism contains statistics on white control of the economy, health, housing, education, the media, and government. It also shows the oppression of minorities in these areas. The areas of wealth, the stock exchange, business, banks, unions, poverty, and unemployment, are discussed in terms of economy. Health matters…

  7. Fact Sheet: Vulnerable Young Children

    Science.gov (United States)

    Shaw, Evelyn, Comp.; Goode, Sue, Comp.

    2008-01-01

    This fact sheet provides data on infants, toddlers and young children who are experiencing high stress as a result of a number of risk factors specifically identified in the Individuals with Disabilities Education Improvement Act of 2004 (IDEA 2004), including substantiated abuse or neglect, foster care placement, homelessness, exposure to family…

  8. Fact Sheets on Institutional Racism.

    Science.gov (United States)

    Foundation for Change, Inc., New York, NY.

    This fact sheet on institutional racism contains statistics on white control of the economy, health, housing, education, the media, and government. It also shows the oppression of minorities in these areas. The areas of wealth, the stock exchange, business, banks, unions, poverty, and unemployment, are discussed in terms of economy. Health matters…

  9. Off-Balance Sheet Financing.

    Science.gov (United States)

    Adams, Matthew C.

    1998-01-01

    Examines off-balance sheet financing, the facilities use of outsourcing for selected needs, as a means of saving operational costs and using facility assets efficiently. Examples of using outside sources for energy supply and food services, as well as partnering with business for facility expansion are provided. Concluding comments address tax…

  10. Polymorphisms of the TNF-α gene interact with plasma fatty acids on inflammatory biomarker profile: a population-based, cross-sectional study in São Paulo, Brazil.

    Science.gov (United States)

    Oki, Erica; Norde, Marina N; Carioca, Antônio A F; Souza, José M P; Castro, Inar A; Marchioni, Dirce M L; Fisberg, Regina M; Rogero, Marcelo M

    2017-06-01

    The aim of the present study was to investigate the relationship of four TNF-α SNP with inflammatory biomarkers and plasma fatty acids (FA), and the interaction among them in a population-based, cross-sectional study in São Paulo, Brazil. A total of 281 subjects, aged >19 and acid (P=0·009), oleic acid (P=0·039), total MUFA (P=0·014), stearoyl-CoA desaturase (SCD) activity index-16 (P=0·007), SCD-18 (P=0·020) and higher levels of PUFA (P=0·046) and DHA (P=0·044). Significant interactions modifying the risk of belonging to the INF cluster were observed with inflammatory cluster as outcome between -857C/T and plasma α-linolenic acid (P=0·026), and also between -308G/A and plasma stearic acid (P=0·044) and total SFA (P=0·040). Our study contributes to knowledge on TNF-α SNP and their association with inflammatory biomarker levels, plasma FA and the interaction among them, of particular interest for the Brazilian population.

  11. Plasma Vitamin D Status and Its Correlation with Risk Factors of Thrombosis, P-selectin and hs-CRP Level in Patients with Venous Thromboembolism; the First Study of Iranian Population.

    Science.gov (United States)

    Entezari-Maleki, Taher; Hajhossein Talasaz, Azita; Salarifar, Mojtaba; Hadjibabaie, Molouk; Javadi, Mohammad Reza; Bozorgi, Ali; Jenab, Yaser; Boroumand, Mohammad Ali; Gholami, Kheirollah

    2014-01-01

    Low plasma level of vitamin D is linked to the increased risk of cardiovascular diseases such as hypertension, diabetes, dyslipidemia and peripheral vascular diseases. Vitamin D deficiency is a worldwide problem that involves Iranian population. To the best of our knowledge, this was the first investigation on venous thromboembolism (VTE) subjects that assessed the correlation of vitamin D level with plasma P-selectin, hs-CRP, and risk factors of thrombosis. In this prospective pilot study, patients with diagnosis of acute deep vein thrombosis and/ or pulmonary embolism were enrolled. All patients' clinical data, demographics and risk factors of thrombosis were evaluated. Plasma level of P-selectin and hs-CRP were measured by ELISA method. Radio immune assay method was used to determine plasma level of 25-hydroxy vitamin D (25(OH) D). In this study, 60 subjects were included. The mean ± SD plasma 25-hydroxy vitamin D level (25(OH) D) of participants was 21.4 ± 14.6 ng/mL. The vitamin D deficiency was detected in 60% of patients. No significant relation was found between the plasma 25(OH)D level and P-selectin and hs-CRP. In multiple regression analysis, there was a significant relationship between the level of 25(OH)D and the patients' age (beta = 0.452; p = 0.001), diabetes (beta = 0.280; p = 0.036) and positive family history of cardiovascular diseases (beta = 0.373; p = 0.003). Vitamin D deficiency is a frequent problem in Iranian VTE patients. Moreover, Plasma level of vitamin D is not associated with P-selectin and hs-CRP in VTE patients.

  12. Global dynamics of the Antarctic ice sheet

    NARCIS (Netherlands)

    Oerlemans, J.

    2002-01-01

    The total mass budget of the Antarctic ice sheet is studied with a simple axi-symmetrical model. The ice-sheet has a parabolic profile resting on a bed that slopes linearly downwards from the centre of the ice sheet into the ocean. The mean ice velocity at the grounding line is assumed to be proport

  13. Peristaltic Pumping near Post-CME Supra-Arcade Current Sheets

    CERN Document Server

    Scott, Roger B; McKenzie, David E

    2013-01-01

    Measurements of temperature and density near supra-arcade current sheets suggest that plasma on unreconnected field lines may experience some degree of "pre-heating" and "pre-densification" prior to their reconnection. Models of patchy reconnection allow for heating and acceleration of plasma along reconnected field lines but do not offer a mechanism for transport of thermal energy across field lines. Here we present a model in which a reconnected flux tube retracts, deforming the surrounding layer of unreconnected field. The deformation creates constrictions that act as peristaltic pumps, driving plasma flow along affected field lines. Under certain circumstances these flows lead to shocks that can extend far out into the unreconnected field, altering the plasma properties in the affected region. These findings have direct implications for observations in the solar corona, particularly in regard to such phenomena as high temperatures near current sheets in eruptive solar flares and wakes seen in the form of ...

  14. Structure and evolution of the current sheet by multi-spacecraft observations

    Energy Technology Data Exchange (ETDEWEB)

    Zhou, X.Y. [Chinese Academy of Sciences, Beijing (China). Inst. of Geophysics; Russell, C.T. [Univ. of California, Los Angeles, CA (United States). Inst. of Geophysics and Planetary Physics; Gosling, J. [Los Alamos National Lab., NM (United States)

    1997-12-31

    On April 22, 1979, from 0840 to 1018 UT, ISEE 1, ISEE 2 and IMP 8 were all in or near the magnetotail current sheet at 17 Re, 16 Re and 35 Re respectively while ISEE 3 monitored the solar wind 206 Re upstream of the Earth. A global perspective of the four spacecraft observations and of the ground magnetic records is presented in this paper. The hyperbolic tangent current sheet model of Harris has been used to calculate the current sheet thickness and to analyze the plasma distribution in the vertical direction. It is found that during this event the current sheet thickness varied from 2.5 Re to 1.5 Re for northward IMF but thinned abruptly to 0.5 Re when the IMF turned southward.

  15. Low frequency eigenmodes of thin anisotropic current sheets and Cluster observations

    Directory of Open Access Journals (Sweden)

    L. M. Zelenyi

    2009-02-01

    Full Text Available The eigenmodes of low frequency perturbations of thin anisotropic current sheets with a finite value of the normal magnetic field, are investigated in this paper. It is shown that two possible polarizations of symmetric and asymmetric modes (sausage and kink exist where the growth rate of instabilities is positive. In addition, we demonstrate that a tearing instability might have a positive growth rate in thin anisotropic current sheets. The class of relatively fast wavy flapping oscillations observed by Cluster is described. The main direction of wave motion coincides with the direction of the current and the typical velocity of this motion is comparable with the plasma drift velocity in the current sheet. The comparison of these characteristics with theoretical predictions of the model of anisotropic thin current sheets, demonstrates that, in principle, the theory adequately describes the observations.

  16. In situ observations of ion scale current sheet and associated electron heating in Earth's magnetosheath turbulence

    Science.gov (United States)

    Chasapis, Alexandros; Retinò, Alessandro; Sahraoui, Fouad; Greco, Antonella; Vaivads, Andris; Sundkvist, David; Canu, Patrick

    2014-05-01

    Magnetic reconnection occurs in thin current sheets that form in turbulent plasmas. Numerical simulations indicate that turbulent reconnection contributes to the dissipation of magnetic field energy and results in particle heating and non-thermal acceleration. Yet in situ measurements are required to determine its importance as a dissipation mechanism at those scales. The Earth's magnetosheath downstream of the quasi-parallel shock is a turbulent near-Earth environment that offers a privileged environment for such a study. Here we present a study of the properties of thin current sheets by using Cluster data. We studied the distribution of the current sheets as a function of their magnetic shear angle, the PVI index and the electron heating. The properties of the observed current sheets were different for high shear (θ > 90 degrees) and low shear current sheets (θ < 90 degrees). These high-shear current sheets account for about ˜ 20% of the total and have an average thickness comparable to the ion inertial length. Enhancement of electron temperature within these current sheets suggest that they are important for local electron heating and energy dissipation.

  17. Current Sheet Formation in a Conical Theta Pinch Faraday Accelerator with Radio-frequency Assisted Discharge

    Science.gov (United States)

    Polzin, Kurt A.; Hallock, Ashley K.; Choueiri, Edgar Y.

    2008-01-01

    Data from an inductive conical theta pinch accelerator are presented to gain insight into the process of inductive current sheet formation in the presence of a preionized background gas produced by a steady-state RF-discharge. The presence of a preionized plasma has been previously shown to allow for current sheet formation at lower discharge voltages and energies than those found in other pulsed inductive accelerator concepts, leading to greater accelerator efficiencies at lower power levels. Time-resolved magnetic probe measurements are obtained for different background pressures and pulse energies to characterize the effects of these parameters on current sheet formation. Indices are defined that describe time-resolved current sheet characteristics, such as the total current owing in the current sheet, the time-integrated total current ('strength'), and current sheet velocity. It is found that for a given electric field strength, maximums in total current, strength, and velocity occur for one particular background pressure. At other pressures, these current sheet indices are considerably smaller. The trends observed in these indices are explained in terms of the principles behind Townsend breakdown that lead to a dependence on the ratio of the electric field to the background pressure. Time-integrated photographic data are also obtained at the same experimental conditions, and qualitatively they compare quite favorably with the time-resolved magnetic field data.

  18. Ice sheet hydrology from observations

    Energy Technology Data Exchange (ETDEWEB)

    Jansson, Peter (Dept. of Physical Geography and Quaternary Geology, Stockholm Univ-, Stockholm (Sweden))

    2010-11-15

    The hydrological systems of ice sheets are complex. Our view of the system is split, largely due to the complexity of observing the systems. Our basic knowledge of processes have been obtained from smaller glaciers and although applicable in general to the larger scales of the ice sheets, ice sheets contain features not observable on smaller glaciers due to their size. The generation of water on the ice sheet surface is well understood and can be satisfactorily modeled. The routing of water from the surface down through the ice is not complicated in terms of procat has been problematic is the way in which the couplings between surface and bed has been accomplished through a kilometer of cold ice, but with the studies on crack propagation and lake drainage on Greenland we are beginning to understand also this process and we know water can be routed through thick cold ice. Water generation at the bed is also well understood but the main problem preventing realistic estimates of water generation is lack of detailed information about geothermal heat fluxes and their geographical distribution beneath the ice. Although some average value for geothermal heat flux may suffice, for many purposes it is important that such values are not applied to sub-regions of significantly higher fluxes. Water generated by geothermal heat constitutes a constant supply and will likely maintain a steady system beneath the ice sheet. Such a system may include subglacial lakes as steady features and reconfiguration of the system is tied to time scales on which the ice sheet geometry changes so as to change pressure gradients in the basal system itself. Large scale re-organization of subglacial drainage systems have been observed beneath ice streams. The stability of an entirely subglacially fed drainage system may hence be perturbed by rapid ice flow. In the case of Antarctic ice streams where such behavior has been observed, the ice streams are underlain by deformable sediments. It is

  19. Ohm's law for a current sheet

    Science.gov (United States)

    Lyons, L. R.; Speiser, T. W.

    1985-01-01

    The paper derives an Ohm's law for single-particle motion in a current sheet, where the magnetic field reverses in direction across the sheet. The result is considerably different from the resistive Ohm's law often used in MHD studies of the geomagnetic tail. Single-particle analysis is extended to obtain a self-consistency relation for a current sheet which agrees with previous results. The results are applicable to the concept of reconnection in that the electric field parallel to the current is obtained for a one-dimensional current sheet with constant normal magnetic field. Dissipated energy goes directly into accelerating particles within the current sheet.

  20. Controllable preparation of vertically standing graphene sheets and their wettability and supercapacitive properties

    Science.gov (United States)

    Zhou, Hai-Tao; Yu, Ning; Zou, Fei; Yao, Zhao-Hui; Gao, Ge; Shen, Cheng-Min

    2016-09-01

    Vertically standing graphene (VSG) sheets have been fabricated by using plasma enhanced chemical vapor deposition (PECVD) method. The lateral size of VSG nanosheets could be well controlled by varying the substrate temperature. The higher temperature usually gives rise to a smaller sheet size. The wettability of VSG films was tuned between hydrophobicity and hydrophilicity by means of oxygen and hydrogen plasma treatment. The supercapacitor electrode made of VSG sheets exhibited an ideal double-layer-capacitor feature and the specific capacitance reached a value up to 9.62 F·m-2. Project supported by the National Basic Research Program of China (Grant No. 2013CBA01603), the National Natural Science Foundation of China (Grant No. 61335006), and the Chinese Academy of Sciences (Grant Nos. 1731300500015 and XDB07030100).

  1. Technology to Market Fact Sheet

    Energy Technology Data Exchange (ETDEWEB)

    None

    2016-02-01

    This fact sheet is an overview of the Technology to Market subprogram at the U.S. Department of Energy SunShot Initiative. The SunShot Initiative’s Technology to Market subprogram builds on SunShot’s record of moving groundbreaking and early-stage technologies and business models through developmental phases to commercialization. Technology to Market targets two known funding gaps: those that occur at the prototype commercialization stage and those at the commercial scale-up stage.

  2. Worsening diastolic function is associated with elevated fasting plasma glucose and increased left ventricular mass in a supra-additive fashion in an elderly, healthy, Swedish population

    DEFF Research Database (Denmark)

    Pareek, Manan; Nielsen, Mette Lundgren; Gerke, Oke;

    2015-01-01

    AIMS: To examine whether increasing fasting plasma glucose (FPG) levels were associated with worsening left ventricular (LV) diastolic function, independently of LV mass index (LVMI) in elderly, otherwise healthy subjects. METHODS AND RESULTS: We tested cross-sectional associations between...

  3. Kinetic model of force-free current sheets with non-uniform temperature

    Science.gov (United States)

    Kolotkov, D. Y.; Vasko, I. Y.; Nakariakov, V. M.

    2015-11-01

    The kinetic model of a one-dimensional force-free current sheet (CS) developed recently by Harrison and Neukirch [Phys. Rev. Lett. 102(13), 135003 (2009)] predicts uniform distributions of the plasma temperature and density across the CS. However, in realistic physical systems, inhomogeneities of these plasma parameters may arise quite naturally due to the boundary conditions or local plasma heating. Moreover, as the CS spatial scale becomes larger than the characteristic kinetic scales (the regime often referred to as the MHD limit), it should be possible to set arbitrary density and temperature profiles. Thus, an advanced model has to allow for inhomogeneities of the macroscopic plasma parameters across the CS, to be consistent with the MHD limit. In this paper, we generalise the kinetic model of a force-free current sheet, taking into account the inhomogeneity of the density and temperature across the CS. In the developed model, the density may either be enhanced or depleted in the CS central region. The temperature profile is prescribed by the density profile, keeping the plasma pressure uniform across the CS. All macroscopic parameters, as well as the distribution functions for the protons and electrons, are determined analytically. Applications of the developed model to current sheets observed in space plasmas are discussed.

  4. Formation of the current sheet in a coronal streamer

    CERN Document Server

    Abbo, Lucia; Lionello, Roberto; Mikić, Zoran; Riley, Pete

    2011-01-01

    The present work is on the study of a coronal streamer observed in March 2008 at high spectral and spatial resolution by the Ultraviolet Coronagraph Spectrometer (UVCS) onboard SOHO. On the basis of a spectroscopic analysis of the O VI doublet, the solar wind plasma parameters are inferred in the extended corona. The analysis accounts for the coronal magnetic topology, extrapolated through a 3D magneto-hydrodynamic model. The results of the analysis show indications on the formation of the current sheet, one of the source regions of the slow coronal wind.

  5. Flapping current sheet motions in magnetotail excited by non-adiabatic ions: case study

    Science.gov (United States)

    Wei, X., Jr.

    2015-12-01

    The current sheet is a crucial region of the magnetotail, where energy reserve and release take place. The origin of the up-down motions of the current sheet, referred to as flapping motions, is among the most fundamental issues of magnetotail dynamics. Observational evidences suggest that the flapping motion is a kind of internal excited kink-like waves, but its particular propagating features such as the low phase speeds and the propagating direction from the tail center toward flanks do not match any local generation mechanisms previously established so far. Here we report observations of the current sheet flapping motions induced by non-adiabatic ions in the magnetic field configurations with a finite guiding component, whose population present periodic hemispherical asymmetries. Three type of current sheet flapping event in this paper will be discussed. This current sheet flapping phenomenon implies that the excitation mechanism of the current sheet flapping motions is a self-circulation process between the non-adiabatic ion population and the current sheet equilibrium itself.

  6. The current sheet tiled and non-adiabatic ions effect on the flapping motion in magnetotail

    Science.gov (United States)

    Wei, XinHua

    2016-04-01

    The current sheet is a crucial region of the magnetotail, where energy reserve and release take place. The origin of the up-down motions of the current sheet, referred to as flapping motions, is among the most fundamental issues of magnetotail dynamics. Observational evidences suggest that the flapping motion is a kind of internal excited kink-like waves, but its particular propagating features such as the low phase speeds and the propagating direction from the tail center toward flanks do not match any local generation mechanisms previously established so far. Here we report observations of the current sheet flapping motions induced by non-adiabatic ions in the magnetic field configurations with a finite guiding component, whose population present periodic hemispherical asymmetries. These flapping motion current sheet cases often observed tiled. The current sheet flapping phenomenon implies that the excitation mechanism of the current sheet flapping motions is a self-circulation process between the non-adiabatic ion population and the current sheet equilibrium itself.

  7. Laboratory Investigations of Current Sheets at the Electron Skin Depth Scale

    Science.gov (United States)

    Vincena, S.; Gekelman, W.

    2005-12-01

    Laboratory Investigations of Current Sheets at the Electron Skin Depth Scale. Theoretical investigations, in situ spacecraft and rocket missions, and laboratory studies form an essential triad for understanding the variety of current sheet phenomena found in space plasmas. In the Large Plasma Device (LAPD) at UCLA, the formation dynamics, equilibrium state, and wave-mediated disruptions of current sheets can be studied with great spatial and temporal resolution using a variety of probes as well as non-invasive laser induced fluorescence and other optical diagnostics. The LAPD is aptly suited for studying current sheets flowing in a magnetized background plasma which is capable of supporting Alfvén waves. The cylindrical device is 20m long and one meter in diameter with a solenoidal magnetic field as high as 3000 Gauss. For the parameters in this experiment, the plasma column is ten shear Alfvén wavelengths along the field and 100 electron inertial lengths (δe) (or 200 ρi) in the perpendicular direction. An electron current sheet is created in the plasma by placing a thin copper plate in the plasma column at one end of the device and pulsing this plate positive with respect to the chamber wall. The current sheet extends for the length of the device and has an initial cross-field size of roughly 45 δe by 0.5δe. A parallel flow of ions is observed with similar dimensions and moves in the same direction as the electrons in the current sheet with a velocity of 0.2 times the ion sound speed. A much weaker sheared perpendicular flow is also measured. Cross-sections of the ion flow are measured at several axial locations over a distance of six meters. Second, as the ion flow increases in magnitude, a much broader (8ρi) density depletion (n=0.25nO) develops around the flow. The gradient scale length of the depletion shortens until the spontaneous growth of drift waves occurs. This disrupts the electron current and ion flow, and leads to cross-field transport of

  8. THEMIS multispacecraft observations of a reconnecting magnetosheath current sheet with symmetric boundary conditions and a large guide field

    Science.gov (United States)

    Øieroset, M.; Phan, T. D.; Shay, M. A.; Haggerty, C. C.; Fujimoto, M.; Angelopoulos, V.; Eastwood, J. P.; Mozer, F. S.

    2017-08-01

    We report three spacecraft observations of a reconnecting magnetosheath current sheet with a guide field of unity, with THEMIS D (THD) and THEMIS E (THE)/THEMIS A (THA) observing oppositely directed reconnection exhausts, indicating the presence of an X line between the spacecraft. The near-constant convective speed of the magnetosheath current sheet allowed the direct translation of the observed time series into spatial profiles. THD observed asymmetries in the plasma density and temperature profiles across the exhaust, characteristics of symmetric reconnection with a guide field. The exhausts at THE and THA, on the other hand, were not the expected mirror image of the THD exhaust in terms of the plasma and field profiles. They consisted of a main outflow at the center of the current sheet, flanked by oppositely directed flows at the two edges of the current sheet, suggesting the presence of a second X line, whose outflow wraps around the outflow from the first X line.

  9. Summary of the evidence of breast cancer service screening outcomes in Europe and first estimate of the benefit and harm balance sheet

    DEFF Research Database (Denmark)

    Paci, Eugenio; Lynge, Elsebeth

    2012-01-01

    To construct a European 'balance sheet' of key outcomes of population-based mammographic breast cancer screening, to inform policy-makers, stakeholders and invited women.......To construct a European 'balance sheet' of key outcomes of population-based mammographic breast cancer screening, to inform policy-makers, stakeholders and invited women....

  10. Measurement of H and H/sub 2/ populations in-situ in a low-temperature plasma by vacuum-ultraviolet laser-absorption spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Schlachter, A.S.; Young, A.T.; Stutzin, G.C.; Stearns, J.W.; Doebele, H.G.; Leung, K.N.; Kunkel, W.B.

    1988-12-01

    A new technique, vacuum-ultraviolet laser-absorption spectroscopy, has been developed to quantitatively determine the absolute density of H and H/sub 2/ within a plasma. The technique is particularly well suited to measurement in a plasma, where high charged particle and photon background complicate other methods of detection. The high selectivity and sensitivity of the technique allows for the measurement of the rotational-vibrational state distribution of H/sub 2/ as well as the translational temperature of the atoms and molecules. The technique has been used to study both pulsed and continuous H/sup /minus// ion-source plasma discharges. H/sub 2/ state distributions in a multicusp ''volume'' H/sup /minus// ion- source plasma show a high degree of internal excitation, with levels up to v = 5 and J = 8 being observed. The method is applicable for a very wide range of plasma conditions. Emission measurements from excited states of H are also reported. 17 refs., 9 figs.

  11. Shock wave interactions with liquid sheets

    Science.gov (United States)

    Jeon, H.; Eliasson, V.

    2017-04-01

    Shock wave interactions with a liquid sheet are investigated by impacting planar liquid sheets of varying thicknesses with a planar shock wave. A square frame was designed to hold a rectangular liquid sheet, with a thickness of 5 or 10 mm, using plastic membranes and cotton wires to maintain the planar shape and minimize bulge. The flat liquid sheet, consisting of either water or a cornstarch and water mixture, was suspended in the test section of a shock tube. Incident shock waves with Mach numbers of M_s = 1.34 and 1.46 were considered. A schlieren technique with a high-speed camera was used to visualize the shock wave interaction with the liquid sheets. High-frequency pressure sensors were used to measure wave speed, overpressure, and impulse both upstream and downstream of the liquid sheet. Results showed that no transmitted shock wave could be observed through the liquid sheets, but compression waves induced by the shock-accelerated liquid coalesced into a shock wave farther downstream. A thicker liquid sheet resulted in a lower peak overpressure and impulse, and a cornstarch suspension sheet showed a higher attenuation factor compared to a water sheet.

  12. Method of manufacturing aluminide sheet by thermomechanical processing of aluminide powders

    Energy Technology Data Exchange (ETDEWEB)

    Hajaligol, Mohammad R.; Scorey, Clive; Sikka, Vinod K.; Deevi, Seetharama C.; Fleishhauer, Grier; Lilly, Jr., A. Clifton; German, Randall M.

    2003-12-09

    A powder metallurgical process of preparing a sheet from a powder having an intermetallic alloy composition such as an iron, nickel or titanium aluminide. The sheet can be manufactured into electrical resistance heating elements having improved room temperature ductility, electrical resistivity, cyclic fatigue resistance, high temperature oxidation resistance, low and high temperature strength, and/or resistance to high temperature sagging. The iron aluminide has an entirely ferritic microstructure which is free of austenite and can include, in weight %, 4 to 32% Al, and optional additions such as .ltoreq.1% Cr, .gtoreq.0.05% Zr .ltoreq.2% Ti, .ltoreq.2% Mo, .ltoreq.1% Ni, .ltoreq.0.75% C, .ltoreq.0.1% B, .ltoreq.1% submicron oxide particles and/or electrically insulating or electrically conductive covalent ceramic particles, .ltoreq.1% rare earth metal, and/or .ltoreq.3% Cu. The process includes forming a non-densified metal sheet by consolidating a powder having an intermetallic alloy composition such as by roll compaction, tape casting or plasma spraying, forming a cold rolled sheet by cold rolling the non-densified metal sheet so as to increase the density and reduce the thickness thereof and annealing the cold rolled sheet. The powder can be a water, polymer or gas atomized powder which is subjecting to sieving and/or blending with a binder prior to the consolidation step. After the consolidation step, the sheet can be partially sintered. The cold rolling and/or annealing steps can be repeated to achieve the desired sheet thickness and properties. The annealing can be carried out in a vacuum furnace with a vacuum or inert atmosphere. During final annealing, the cold rolled sheet recrystallizes to an average grain size of about 10 to 30 .mu.m. Final stress relief annealing can be carried out in the B2 phase temperature range.

  13. Method of manufacturing aluminide sheet by thermomechanical processing of aluminide powders

    Energy Technology Data Exchange (ETDEWEB)

    Hajaligol, Mohammad R. (Midlothian, VA); Scorey, Clive (Cheshire, CT); Sikka, Vinod K. (Oak Ridge, TN); Deevi, Seetharama C. (Midlothian, VA); Fleischhauer, Grier (Midlothian, VA); Lilly, Jr., A. Clifton (Chesterfield, VA); German, Randall M. (State College, PA)

    2000-01-01

    A powder metallurgical process of preparing a sheet from a powder having an intermetallic alloy composition such as an iron, nickel or titanium aluminide. The sheet can be manufactured into electrical resistance heating elements having improved room temperature ductility, electrical resistivity, cyclic fatigue resistance, high temperature oxidation resistance, low and high temperature strength, and/or resistance to high temperature sagging. The iron aluminide has an entirely ferritic microstructure which is free of austenite and can include, in weight %, 4 to 32% Al, and optional additions such as .ltoreq.1% Cr, .gtoreq.0.05% Zr.ltoreq.2% Ti, .ltoreq.2% Mo, .ltoreq.1% Ni, .ltoreq.0.75% C, .ltoreq.0.1% B, .ltoreq.1% submicron oxide particles and/or electrically insulating or electrically conductive covalent ceramic particles, .ltoreq.1% rare earth metal, and/or .ltoreq.3% Cu. The process includes forming a non-densified metal sheet by consolidating a powder having an intermetallic alloy composition such as by roll compaction, tape casting or plasma spraying, forming a cold rolled sheet by cold rolling the non-densified metal sheet so as to increase the density and reduce the thickness thereof and annealing the cold rolled sheet. The powder can be a water, polymer or gas atomized powder which is subjecting to sieving and/or blending with a binder prior to the consolidation step. After the consolidation step, the sheet can be partially sintered. The cold rolling and/or annealing steps can be repeated to achieve the desired sheet thickness and properties. The annealing can be carried out in a vacuum furnace with a vacuum or inert atmosphere. During final annealing, the cold rolled sheet recrystallizes to an average grain size of about 10 to 30 .mu.m. Final stress relief annealing can be carried out in the B2 phase temperature range.

  14. Method of manufacturing aluminide sheet by thermomechanical processing of aluminide powders

    Energy Technology Data Exchange (ETDEWEB)

    Hajaligol, M.R.; Scorey, C.; Sikka, V.K.; Deevi, S.C.; Fleischhauer, G.; Lilly, A.C. Jr.; German, R.M.

    2000-02-29

    A powder metallurgical process is disclosed of preparing a sheet from a powder having an intermetallic alloy composition such as an iron, nickel or titanium aluminide. The sheet can be manufactured into electrical resistance heating elements having improved room temperature ductility, electrical resistivity, cyclic fatigue resistance, high temperature oxidation resistance, low and high temperature strength, and/or resistance to high temperature sagging. The iron aluminide has an entirely ferritic microstructure which is free of austenite and can include, in weight %, 4 to 32% Al, and optional additions such as {<=}1% Cr, {>=}0.05% Zr{<=}2% Ti, {<=}2% Mo, {<=}1% Ni, {<=}0.75% C, {<=}0.1% B, {<=}1% submicron oxide particles and/or electrically insulating or electrically conductive covalent ceramic particles, {<=}1% rare earth metal, and/or {<=}3% Cu. The process includes forming a non-densified metal sheet by consolidating a powder having an intermetallic alloy composition such as by roll compaction, tape casting or plasma spraying, forming a cold rolled sheet by cold rolling the non-densified metal sheet so as to increase the density and reduce the thickness thereof and annealing the cold rolled sheet. The powder can be a water, polymer or gas atomized powder which is subjecting to sieving and/or blending with a binder prior to the consolidation step. After the consolidation step, the sheet can be partially sintered. The cold rolling and/or annealing steps can be repeated to achieve the desired sheet thickness and properties. The annealing can be carried out in a vacuum furnace with a vacuum or inert atmosphere. During final annealing, the cold rolled sheet recrystallizes to an average grain size of about 10 to 30 {mu}m. Final stress relief annealing can be carried out in the B2 phase temperature range.

  15. EDITORIAL: Plasma jets and plasma bullets Plasma jets and plasma bullets

    Science.gov (United States)

    Kong, M. G.; Ganguly, B. N.; Hicks, R. F.

    2012-06-01

    to 1990 with only 31 papers per year on average, and a total of some 1300 papers, precedes a considerable growth of some 35-50% in research activity every five years, over the last 20 years or so. As shown in the table, the annual dissemination of the field is more than 1600 papers and the total number of papers is in excess of 20000. This upwards trajectory is typical of a strong and growing subject area in physical science, with considerable capacity in both fundamental science and applications. PeriodNumber of papersPapers per annum 1948-1990130031 1991-19952279456 1996-20003447689 2001-20054571914 2006-201066401328 2011 1658 In many of the dense plasma jets discussed above, strong physical forces generated by the plasma are often desired and this favours plasma generation at elevated gas pressure, including atmospheric pressure, which favours a high level of gas ionization. Historically it has been challenging to reduce and control the strong physical forces in high-pressure plasmas for applications where these are unwanted, for example, surface modification of polymeric sheets [5]. Indeed, there is a real need for a vast range of material processing applications at temperatures below 100oC (or below 400 K) and this favours atmospheric-pressure plasma jets sustained far from thermal equilibrium with the dissipated electrical energy largely used not in heat generation but in unleashing non-equilibrium chemical reactions. The long-standing difficulty of effectively controlling the level of gas ionization at atmospheric pressure was overcome by the technological breakthrough of achieving atmospheric-pressure glow discharges in the late 1980s [6]. A related challenge stemming from high collisionality of atmospheric-pressure plasmas (v >> ω0) means that large-area plasmas sustained between parallel-plate electrodes are very susceptible to strong plasma instabilities when molecular gases are introduced for processing applications. This led to an effective

  16. Plasma in the near Venus tail: Venus Express observations

    Science.gov (United States)

    Dubinin, E.; Fraenz, M.; Zhang, T. L.; Woch, J.; Wei, Y.; Fedorov, A.; Barabash, S.; Lundin, R.

    2013-12-01

    Although Venus has no global intrinsic magnetic fields, it possesses a long magnetotail of induced origin. The topology of the tail is determined by the interplanetary magnetic field orientation. We present recent plasma and magnetic field observations in the near Venus tail (X≥-3RV) made by the Venus Express spacecraft. We show that ion acceleration in the Venus plasma sheet is produced by the slingshot effect of the draping magnetic field lines, though some features as differential streaming of different ion species point to the existence of other forces. We explain a bell shape of ion spectrograms while the spacecraft crosses the current sheet. The absence of a balance between the lobe magnetic pressure and thermal pressure of plasma in the plasma sheet indicates a dynamic rather than a static equilibrium in the Venus magnetotail. A strong asymmetry of the plasma sheet is controlled by the direction of the motional electric field in the upstream solar wind. In the hemisphere pointed in the direction of the motional electric field, the j×B force accelerates plasma tailward supplying the plasma sheet, while in the opposite hemisphere, the flow pattern occurs less regularly with smaller speeds but higher number densities.

  17. Teen Sexual Activity, Pregnancy and Childbearing among Latinos in the United States. Fact Sheet.

    Science.gov (United States)

    National Campaign To Prevent Teen Pregnancy, Washington, DC.

    The Latino population is the fastest-growing major racial/ethnic group in the United States. By 2020, approximately 16 percent of the population will be Latino. This increase will be even more pronounced among teens. This fact sheet summarizes data from the National Vital Statistics Reports on reported sexual activity, pregnancy rates, and…

  18. Morphology and Density Structure of Post-CME Current Sheets

    Science.gov (United States)

    Vrsnak, B.; Poletto, G.; Vujic, E.; Vourlidas, A.

    2009-01-01

    Eruption of a coronal mass ejection (CME) is believed to drag and open the coronal magnetic field, presumably leading to the formation of a large-scale current sheet and field relaxation by magnetic reconnection. This paper analyzes the physical characteristics of ray-like coronal features formed in the aftermath of CMEs, to confirm whether interpreting such phenomena in terms of a reconnecting current sheet is consistent with observations. Methods: The study focuses on UVCS/SOHO and LASCO/SOHO measurements of the ray width, density excess, and coronal velocity field as a function of the radial distance. The morphology of the rays implies that they are produced by Petschek-like reconnection in the large-scale current sheet formed in the wake of CME. The hypothesis is supported by the flow pattern, often showing outflows along the ray, and sometimes also inflows into the ray. The inferred inflow velocities range from 3 to 30 km/s, and are consistent with the narrow opening-angle of rays, which add up to a few degrees. The density of rays is an order of magnitude higher than in the ambient corona. The model results are consistent with the observations, revealing that the main cause of the density excess in rays is a transport of the dense plasma from lower to higher heights by the reconnection outflow.

  19. Neutral sheet crossings by ISEE-3 in the distant magnetotail

    Science.gov (United States)

    Heikkila, W. J.; Slavin, J. A.; Smith, E. J.; Baker, D. N.; Zwickl, R. D.

    1986-01-01

    The magnetic field data from ISEE-3 in the distant magnetotail at crossings of the field reversal (or neutral sheet) region are analyzed to determine the instantaneous direction of the normal component B(z) at the crossing. Crossings in the middle of the aberrated magnetotail near the apogee A2 of the first deep-tail orbit of ISEE-3 in January-February, 1983 were selected. Data for an interval of one hour is discussed at length to illustrate some of the difficulties that can occur. One particular smooth crossing at 15:56 UT, February 4, 1983, shows that complicated microstructure can occur in times shorter than one minute; averaging over long times may eliminate essential information for this purpose. By inspecting the magnetic field data at the highest resolution, however, it is shown that the direction of the plasma sheet flows and the sense of B(z) across the neutral sheet do not always agree with the reconnection models. Rather, they indicate that the low latitude boundary layer may play a significant role in the dynamics of the magnetotail.

  20. Spatial Offsets in Flare-CME Current Sheets

    Science.gov (United States)

    Raymond, John C.; Giordano, Silvio; Ciaravella, Angela

    2017-07-01

    Magnetic reconnection plays an integral part in nearly all models of solar flares and coronal mass ejections (CMEs). The reconnection heats and accelerates the plasma, produces energetic electrons and ions, and changes the magnetic topology to form magnetic flux ropes and to allow CMEs to escape. Structures that appear between flare loops and CME cores in optical, UV, EUV, and X-ray observations have been identified as current sheets and have been interpreted in terms of the nature of the reconnection process and the energetics of the events. Many of these studies have used UV spectral observations of high temperature emission features in the [Fe xviii] and Si xii lines. In this paper, we discuss several surprising cases in which the [Fe xviii] and Si xii emission peaks are spatially offset from each other. We discuss interpretations based on asymmetric reconnection, on a thin reconnection region within a broader streamer-like structure, and on projection effects. Some events seem to be easily interpreted as the projection of a sheet that is extended along the line of sight that is viewed an angle, but a physical interpretation in terms of asymmetric reconnection is also plausible. Other events favor an interpretation as a thin current sheet embedded in a streamer-like structure.

  1. Current Sheets in the Heliosheath: Voyager 1, 2009

    Science.gov (United States)

    Burlaga, L. F.; Ness, N. F.

    2011-01-01

    We identified all of the current sheets for which we have relatively complete and accurate magnetic field (B) data from Voyager 1 (V1) from days of year (DOYs) 1 to 331, 2009, which were obtained deep in the heliosheath between 108.5 and 111.8 AU. Three types of current sheets were found: (1) 15 proton boundary layers (PBLs), (2) 10 and 3 magnetic holes and magnetic humps, respectively, and (3) 3 sector boundaries. The magnetic field strength changes across PBL, and the profile B(t) is linearly related to the hyperbolic tangent function, but the direction of B does not change. For each of the three sector boundaries, B rotated in a plane normal to the minimum variance direction, and the component of B along the minimum variance direction was zero within the uncertainties, indicating that the sector boundaries were tangential discontinuities. The structure of the sector boundaries was not as simple as that for PBLs. The average thickness of magnetic holes and humps (approx.30 RL) was twice that of the PBLs (approx.15 RL). The average thickness of the current sheets associated with sector boundaries was close to the thickness of the PBLs. Our observations are consistent with the hypothesis that magnetic holes and humps are solitons, which are initiated by the mirror mode instability, and evolve by nonlinear kinetic plasma processes to pressure balanced structures maintained by magnetization currents and proton drift currents in the gradients of B.

  2. Paper-based plasma sanitizers

    Science.gov (United States)

    Xie, Jingjin; Chen, Qiang; Suresh, Poornima; Roy, Subrata; White, James F.; Mazzeo, Aaron D.

    2017-05-01

    This work describes disposable plasma generators made from metallized paper. The fabricated plasma generators with layered and patterned sheets of paper provide a simple and flexible format for dielectric barrier discharge to create atmospheric plasma without an applied vacuum. The porosity of paper allows gas to permeate its bulk volume and fuel plasma, while plasma-induced forced convection cools the substrate. When electrically driven with oscillating peak-to-peak potentials of ±1 to ±10 kV, the paper-based devices produced both volume and surface plasmas capable of killing microbes. The plasma sanitizers deactivated greater than 99% of Saccharomyces cerevisiae and greater than 99.9% of Escherichia coli cells with 30 s of noncontact treatment. Characterization of plasma generated from the sanitizers revealed a detectable level of UV-C (1.9 nWṡcm-2ṡnm-1), modest surface temperature (60 °C with 60 s of activation), and a high level of ozone (13 ppm with 60 s of activation). These results deliver insights into the mechanisms and suitability of paper-based substrates for active antimicrobial sanitization with scalable, flexible sheets. In addition, this work shows how paper-based generators are conformable to curved surfaces, appropriate for kirigami-like “stretchy” structures, compatible with user interfaces, and suitable for sanitization of microbes aerosolized onto a surface. In general, these disposable plasma generators represent progress toward biodegradable devices based on flexible renewable materials, which may impact the future design of protective garments, skin-like sensors for robots or prosthetics, and user interfaces in contaminated environments.

  3. Plasma turbulence

    Energy Technology Data Exchange (ETDEWEB)

    Horton, W. [Univ. of Texas, Austin, TX (United States). Inst. for Fusion Studies; Hu, G. [Globalstar LP, San Jose, CA (United States)

    1998-07-01

    The origin of plasma turbulence from currents and spatial gradients in plasmas is described and shown to lead to the dominant transport mechanism in many plasma regimes. A wide variety of turbulent transport mechanism exists in plasmas. In this survey the authors summarize some of the universally observed plasma transport rates.

  4. AI applications in sheet metal forming

    CERN Document Server

    Hussein, Hussein

    2017-01-01

    This book comprises chapters on research work done around the globe in the area of artificial intelligence (AI) applications in sheet metal forming. The first chapter offers an introduction to various AI techniques and sheet metal forming, while subsequent chapters describe traditional procedures/methods used in various sheet metal forming processes, and focus on the automation of those processes by means of AI techniques, such as KBS, ANN, GA, CBR, etc. Feature recognition and the manufacturability assessment of sheet metal parts, process planning, strip-layout design, selecting the type and size of die components, die modeling, and predicting die life are some of the most important aspects of sheet metal work. Traditionally, these activities are highly experience-based, tedious and time consuming. In response, researchers in several countries have applied various AI techniques to automate these activities, which are covered in this book. This book will be useful for engineers working in sheet metal industri...

  5. Force-free collisionless current sheet models with non-uniform temperature and density profiles

    Science.gov (United States)

    Wilson, F.; Neukirch, T.; Allanson, O.

    2017-09-01

    We present a class of one-dimensional, strictly neutral, Vlasov-Maxwell equilibrium distribution functions for force-free current sheets, with magnetic fields defined in terms of Jacobian elliptic functions, extending the results of Abraham-Shrauner [Phys. Plasmas 20, 102117 (2013)] to allow for non-uniform density and temperature profiles. To achieve this, we use an approach previously applied to the force-free Harris sheet by Kolotkov et al. [Phys. Plasmas 22, 112902 (2015)]. In one limit of the parameters, we recover the model of Kolotkov et al. [Phys. Plasmas 22, 112902 (2015)], while another limit gives a linear force-free field. We discuss conditions on the parameters such that the distribution functions are always positive and give expressions for the pressure, density, temperature, and bulk-flow velocities of the equilibrium, discussing the differences from previous models. We also present some illustrative plots of the distribution function in velocity space.

  6. 40 CFR 124.8 - Fact sheet.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 21 2010-07-01 2010-07-01 false Fact sheet. 124.8 Section 124.8... DECISIONMAKING General Program Requirements § 124.8 Fact sheet. (Applicable to State programs, see §§ 123.25 (NPDES), 145.11 (UIC), 233.26 (404), and 271.14 (RCRA).) (a) A fact sheet shall be prepared for every...

  7. Development of Auto Sheets in Baosteel

    Institute of Scientific and Technical Information of China (English)

    LuJiangxin; WangLi

    2005-01-01

    The development trends of auto sheets in recent years are summarized with regard to the envirorunental regulations, market demands and strategy of the steel industry. The growth of domestic auto industry and demands for auto sheets are also briefed. The current status of development of Bake hardenable steel, Isotropic steel for outer panels and Transformation induced plasticity steel, dual phase steel for structural parts in Baosteel is introduced and the future of auto sheets in Baosteel is forecasted.

  8. A Monetary Analysis of Balance Sheet Policies

    OpenAIRE

    2013-01-01

    We augment a standard macroeconomic model to analyze the effects and limitations of balance sheet policies. We show that the central bank can stimulate real activity by changing the size or the composition of its balance sheet, when interest rate policy is ineffective. Specifically, the central bank can stabilize the economy by increasing money supply against eligible assets even when the policy rate is at the zero lower bound. By changing the composition of its balance sheet, it can affect i...

  9. Plasma sCD36 is associated with markers of atherosclerosis, insulin resistance and fatty liver in a nondiabetic healthy population

    DEFF Research Database (Denmark)

    Handberg, A; Højlund, K; Gastaldelli, A;

    2012-01-01

    Insulin resistance is associated with increased CD36 expression in a number of tissues. Moreover, excess macrophage CD36 may initiate atherosclerotic lesions. The aim of this study was to determine whether plasma soluble CD36 (sCD36) was associated with insulin resistance, fatty liver and carotid...

  10. Research Program of International Geophysical Year (Igy-1957 Have Ended In the Millennium Beginning By Discovery of the Theoretical Current Sheets in the Nature

    Directory of Open Access Journals (Sweden)

    Ostapenko V. A.

    2016-08-01

    Full Text Available We declare about the discovery in the Nature of theoretical current sheets by S. I. Syrovatskij. The first “natural” current sheet was discovered in flare spectrum, calculated and researched experimentally. The current sheets (CS are found in chromosphere and downward levels in optical range data. The main problem of physics of solar flares has been solved. Magnetic field energy is a primary source of active processes in solar plasma. Current sheet (CS of S. I. Syrovatskij is the mechanism of magnetic energy transformation into plasma energy. The current sheet is not discovered in a flare, as expected. As a matter of fact, solar flare is in itself a current sheet, its direct observed development in chromosphere plasma. Continuous current sheet radiation is the «black» (BLF and the «white» (WLF flare (like light of Sun photosphere. It is the negative hydrogen ion excitation upon reaching hydrogen plasma density of ˃5 1017 cm -3

  11. Shape Optimization of Swimming Sheets

    Energy Technology Data Exchange (ETDEWEB)

    Wilkening, J.; Hosoi, A.E.

    2005-03-01

    The swimming behavior of a flexible sheet which moves by propagating deformation waves along its body was first studied by G. I. Taylor in 1951. In addition to being of theoretical interest, this problem serves as a useful model of the locomotion of gastropods and various micro-organisms. Although the mechanics of swimming via wave propagation has been studied extensively, relatively little work has been done to define or describe optimal swimming by this mechanism.We carry out this objective for a sheet that is separated from a rigid substrate by a thin film of viscous Newtonian fluid. Using a lubrication approximation to model the dynamics, we derive the relevant Euler-Lagrange equations to optimize swimming speed and efficiency. The optimization equations are solved numerically using two different schemes: a limited memory BFGS method that uses cubic splines to represent the wave profile, and a multi-shooting Runge-Kutta approach that uses the Levenberg-Marquardt method to vary the parameters of the equations until the constraints are satisfied. The former approach is less efficient but generalizes nicely to the non-lubrication setting. For each optimization problem we obtain a one parameter family of solutions that becomes singular in a self-similar fashion as the parameter approaches a critical value. We explore the validity of the lubrication approximation near this singular limit by monitoring higher order corrections to the zeroth order theory and by comparing the results with finite element solutions of the full Stokes equations.

  12. Unsteady magnetic reconnection in laboratory experiments with current sheets

    Science.gov (United States)

    Frank, Anna

    2009-11-01

    According to present notion, unsteady magnetic reconnection in current sheets (CS) is basic to dramatic natural phenomena: solar and stellar flares, substorms in the Earth and other planetary magnetospheres, as well as to disruptive instabilities in tokamak plasmas. We present a review of laboratory experiments studying evolution of CS formed in 3D and 2D magnetic configurations with an X line, in the CS-3D device. Usually CS exists during an extended period in a metastable stage, without essential changes of its structure and parameters. Under certain conditions this stage may be suddenly interrupted by unsteady phase of magnetic reconnection, which manifests itself in a rapid change of the magnetic field topology, current redistribution, excitation of pulsed electric fields, and other dynamic effects. The unsteady phase results in effective conversion of magnetic energy into the energy of plasma and accelerated particles, and may finally bring about the CS disruption. In the context of the solar flares, a metastable CS is associated with a pre-flare situation, while CS disruption -- with the flare itself. The physical mechanisms triggering the unsteady magnetic reconnection in the laboratory produced current sheets are discussed. Supported by the Russian Foundation for Basic Research (project # 09-02-00971).

  13. A technique for generating consistent ice sheet initial conditions for coupled ice-sheet/climate models

    Directory of Open Access Journals (Sweden)

    J. G. Fyke

    2013-04-01

    Full Text Available A new technique for generating ice sheet preindustrial 1850 initial conditions for coupled ice-sheet/climate models is developed and demonstrated over the Greenland Ice Sheet using the Community Earth System Model (CESM. Paleoclimate end-member simulations and ice core data are used to derive continuous surface mass balance fields which are used to force a long transient ice sheet model simulation. The procedure accounts for the evolution of climate through the last glacial period and converges to a simulated preindustrial 1850 ice sheet that is geometrically and thermodynamically consistent with the 1850 preindustrial simulated CESM state, yet contains a transient memory of past climate that compares well to observations and independent model studies. This allows future coupled ice-sheet/climate projections of climate change that include ice sheets to integrate the effect of past climate conditions on the state of the Greenland Ice Sheet, while maintaining system-wide continuity between past and future climate simulations.

  14. Observations at the planet Mercury by the plasma electron experiment, Mariner 10

    Science.gov (United States)

    Ogilvie, K. W.; Scudder, J. D.; Vasyliunas, V. M.; Hartle, R. E.; Siscoe, G. L.

    1976-01-01

    Plasma electron observations made onboard Mariner 10 are reported. Three encounters with the planet Mercury show that the planet interacts with the solar wind to form a bow shock and a permanent magnetosphere. The observations provide a determination of the dimensions and properties of the magnetosphere, independently of and in general agreement with magnetometer observations. The magnetosphere of Mercury appears to be similar in shape to that of the Earth but much smaller in relation to the size of the planet. Electron populations similar to those found in the Earth's magnetotail, within the plasma sheet and adjacent regions, were observed at Mercury; both their spatial location and the electron energy spectra within them bear qualitative and quantitative resemblance to corresponding observations at the Earth. The magnetosphere of Mercury resembles to a marked degree a reduced version of that of the Earth, with no significant differences of structure.

  15. Plasma harmonics

    CERN Document Server

    Ganeev, Rashid A

    2014-01-01

    Preface; Why plasma harmonics? A very brief introduction Early stage of plasma harmonic studies - hopes and frustrations New developments in plasma harmonics studies: first successes Improvements of plasma harmonics; Theoretical basics of plasma harmonics; Basics of HHG Harmonic generation in fullerenes using few-cycle pulsesVarious approaches for description of observed peculiarities of resonant enhancement of a single harmonic in laser plasmaTwo-colour pump resonance-induced enhancement of odd and even harmonics from a tin plasmaCalculations of single harmonic generation from Mn plasma;Low-o

  16. An ice sheet model validation framework for the Greenland ice sheet

    NARCIS (Netherlands)

    Price, Stephen F.; Hoffman, Matthew J.; Bonin, Jennifer A.; Howat, Ian M.; Neumann, Thomas; Saba, Jack; Tezaur, Irina; Guerber, Jeffrey; Chambers, Don P.; Evans, Katherine J.; Kennedy, Joseph H.; Lenaerts, Jan; Lipscomb, William H.; Perego, Mauro; Salinger, Andrew G.; Tuminaro, Raymond S.; Van Den Broeke, Michiel R.; Nowicki, Sophie M J

    2017-01-01

    We propose a new ice sheet model validation framework - the Cryospheric Model Comparison Tool (CmCt) - that takes advantage of ice sheet altimetry and gravimetry observations collected over the past several decades and is applied here to modeling of the Greenland ice sheet. We use realistic

  17. ISSM: Ice Sheet System Model

    Science.gov (United States)

    Larour, Eric; Schiermeier, John E.; Seroussi, Helene; Morlinghem, Mathieu

    2013-01-01

    In order to have the capability to use satellite data from its own missions to inform future sea-level rise projections, JPL needed a full-fledged ice-sheet/iceshelf flow model, capable of modeling the mass balance of Antarctica and Greenland into the near future. ISSM was developed with such a goal in mind, as a massively parallelized, multi-purpose finite-element framework dedicated to ice-sheet modeling. ISSM features unstructured meshes (Tria in 2D, and Penta in 3D) along with corresponding finite elements for both types of meshes. Each finite element can carry out diagnostic, prognostic, transient, thermal 3D, surface, and bed slope simulations. Anisotropic meshing enables adaptation of meshes to a certain metric, and the 2D Shelfy-Stream, 3D Blatter/Pattyn, and 3D Full-Stokes formulations capture the bulk of the ice-flow physics. These elements can be coupled together, based on the Arlequin method, so that on a large scale model such as Antarctica, each type of finite element is used in the most efficient manner. For each finite element referenced above, ISSM implements an adjoint. This adjoint can be used to carry out model inversions of unknown model parameters, typically ice rheology and basal drag at the ice/bedrock interface, using a metric such as the observed InSAR surface velocity. This data assimilation capability is crucial to allow spinning up of ice flow models using available satellite data. ISSM relies on the PETSc library for its vectors, matrices, and solvers. This allows ISSM to run efficiently on any parallel platform, whether shared or distrib- ISSM: Ice Sheet System Model NASA's Jet Propulsion Laboratory, Pasadena, California uted. It can run on the largest clusters, and is fully scalable. This allows ISSM to tackle models the size of continents. ISSM is embedded into MATLAB and Python, both open scientific platforms. This improves its outreach within the science community. It is entirely written in C/C++, which gives it flexibility in its

  18. Metastability of collisionless current sheets. Hannes Alfven Lecture on behalf of Albert Galeev

    Science.gov (United States)

    Zelenyi, L.; Galeev, A.

    2009-04-01

    Complicated magnetic configurations containing numerous magnetic field reversals are widespread in nature. Each of such reversals is supported by corresponding current sheet (CS) which could often have very small thickness comparable to ion skin depth. Since the beginning of Space Age "in situ" investigations of current sheets in the Earth's magnetosphere (magnetopause and magnetotail) acquired one of the highest priorities in national space programs and became one of the cornerstones of various international activities, like ISTP, IACG, and ILWS, which appeared to be very effective. Intense theoretical efforts were undertaken by theorists all over the world to develop both equilibrium models of current sheets and analyze its stability and further nonlinear evolution. Lack of collisions and smallness of many characteristic scales in comparison with ion Larmor radius made an application of straightforward MHD approach dramatically questionable. Professor Alfven was one of the first who suggested in 1968 simple but very physical self-consistent particle model of CS. One of the most intriguing features of current sheets in collisionless plasma is their ability to accumulate tremendous amounts of magnetic energy (1015 J for magnetospheric substorms , 1024 J for solar flare associated sheets) and then suddenly sometimes almost explosively release them. We will demonstrate in this talk that such METASTABILITY is a principal intrinsic feature of current sheets in hot plasma. Very intense theoretical debates of 80-ies and late 90-ies resulted in some consensus that current sheets with the small component of magnetic field normal to their plane become overstable for spontaneous reconnection (i.e. versus the development of ion tearing mode). Analysis of INTERBALL and especially 4- point CLUSTER data have shown that real current sheets observed in the Earth's magnetotail very rarely resemble simplistic HARRIS current sheets which have been used for an early stability

  19. Plasma alkylresorcinols reflect gluten intake and distinguish between gluten-rich and gluten-poor diets in a population at risk of metabolic syndrome

    DEFF Research Database (Denmark)

    Lind, Mads Vendelbo; Madsen, Mia Linda; Rumessen, Jüri J

    2016-01-01

    BACKGROUND: Many patients with celiac disease experience difficulties in adherence to a gluten-free diet. Methods for testing compliance to a gluten-free diet are costly and cumbersome. Thus, a simple biomarker of gluten intake is needed in a clinical setting and will be useful for epidemiologic...... studies investigating wider effects of gluten intake. OBJECTIVE: The aim was to evaluate plasma total alkylresorcinol concentrations as a measure of gluten intake. METHODS: In this randomized, controlled, crossover intervention study in 52 Danish adults with features of the metabolic syndrome, we compared...... 8 wk of a gluten-rich and gluten-poor diet separated by a washout period of ≥6 wk. We measured fasting plasma concentrations of alkylresorcinols to determine if they reflected differences in gluten intake as a secondary outcome of the original study. In addition, we investigated in 118 Danish adults...

  20. Electric fields and double layers in plasmas

    Science.gov (United States)

    Singh, Nagendra; Thiemann, H.; Schunk, R. W.

    1987-05-01

    Various mechanisms for driving double layers in plasmas are briefly described, including applied potential drops, currents, contact potentials, and plasma expansions. Some dynamical features of the double layers are discussed. These features, as seen in simulations, laboratory experiments, and theory, indicate that double layers and the currents through them undergo slow oscillations which are determined by the ion transit time across an effective length of the system in which double layers form. It is shown that a localized potential dip forms at the low potential end of a double layer, which interrupts the electron current through it according to the Langmuir criterion, whenever the ion flux into the double is disrupted. The generation of electric fields perpendicular to the ambient magnetic field by contact potentials is also discussed. Two different situations were considered; in one, a low-density hot plasma is sandwiched between high-density cold plasmas, while in the other a high-density current sheet permeates a low-density background plasma. Perpendicular electric fields develop near the contact surfaces. In the case of the current sheet, the creation of parallel electric fields and the formation of double layers are also discussed when the current sheet thickness is varied. Finally, the generation of electric fields and double layers in an expanding plasma is discussed.

  1. Identification of a liver cirrhosis signature in plasma for predicting hepatocellular carcinoma risk in a population-based cohort of hepatitis B carriers.

    Science.gov (United States)

    Liu, Chia-Chi; Wang, Ya-Hui; Chuang, Eric Y; Tsai, Mong-Hsun; Chuang, Ya-Hui; Lin, Chih-Lin; Liu, Chun-Jen; Hsiao, Bo-Yu; Lin, Shi-Ming; Liu, Li-Yu; Yu, Ming-Whei

    2014-01-01

    Liver cirrhosis is a critical state in the natural course of hepatocellular carcinoma (HCC). We sought to investigate the potential of in-depth proteomics to reveal plasma protein signatures that reflect common networks/pathways of liver cirrhosis, and to determine whether the cirrhosis-related signature in plasma is linked to the development of HCC among hepatitis B virus (HBV) carriers. We first compared plasma protein profiles using a 174-antibody microarray system between three groups of HBV carriers with different Child's grades of cirrhosis, which revealed a panel of 45 differentially expressed proteins with a high accuracy for discriminating Child's B/C. Ingenuity Pathway Analysis identified two main up-regulated networks connecting the 45 proteins that were most enriched for genes in the pathway of hepatic stellate cell activation. A parsimonious subset of 11 pathway-based proteins was then selected for quantification to correlate with HCC risk among 49 HCC cases and 50 controls in a nested case-control study within a 16-yr follow-up cohort of HBV carriers. A high risk score derived from a principal component analysis, which was used to extract the cluster structure of the 11 proteins, was associated with HCC (odds ratio = 4.83, 95% confidence interval: 1.26-18.56) even after adjustment for viral and clinical variables, implying the involvement of a pattern of coordinated proteins. Stepwise logistic regression on the 11 proteins revealed ICAM-2 as an independent predictor for HCC. These findings may give further insight into the pathobiology of hepatocarcinogenesis, allow testing of the cirrhosis-related plasma protein signature as a potential predictive biomarker for HCC.

  2. Observational Study on Current Sheet of Magnetic Reconnection in Two Solar Eruptions

    Science.gov (United States)

    Qiang-wei, Cai; Ning, Wu; Jun, Lin

    2016-07-01

    The coronal magnetic configuration behind coronal mass ejections (CMEs) can commonly be stretched severely, thus to push the magnetic fields with opposite polarities to approach each other, and to form a current sheet of magnetic reconnection. The current sheet in solar eruptions is not only an important region to convert the magnetic free energy into thermal energy, plasma kinetic energy, and energetic particle beams, but also plays a role to connect CMEs and flares. In the CME events of 2003 January 3 and 2003 November 4, the development of current sheet has been observed in both cases. We have investigated the dynamic features and physical properties of current sheet in the two events, based on the data of LASCO (Large Angle and Spectrometric Coronagraph) and UVCS (Ultraviolet Coronagraph Spectrometer) on board of SOHO (Solar and Heliospheric Observatory), and the Hα data from BBSO (Big Bear Solar Observatory) and YNAO (Yunnan Astronomical Observatory). The existence of ions with a high degree of ionization, such as Fe+17 and Si+11, indicates a high temperature up to 3×106 ∼5×106 K in the region of current sheet. A direct measurement shows that the thickness of current sheet varies between 1.3×104 and 1.1×105 km, which increases first and then decreases with time. Using the CHIANTI code (v.7.1), we have further calculated the average values of electron temperature and corresponding emission measure (EM) respectively to be 3.86×106 K and 6.1×1024 cm-5 in the current sheet of the 2003 January 3 event. We also find that the current sheet twisted forth and back quasi-periodically during the eruption event on 2003 November 4 by analyzing the observational data from SOHO/UVCS.

  3. Concentrating Solar Power Fact Sheet

    Energy Technology Data Exchange (ETDEWEB)

    None

    2015-12-01

    This fact sheet is an overview of the Concentrating Solar Power (CSP) subprogram at the U.S. Department of Energy SunShot Initiative. CSP is a dispatchable, renewable energy option that uses mirrors to focus and concentrate sunlight onto a receiver, from which a heat transfer fluid carries the intense thermal energy to a power block to generate electricity. CSP systems can store solar energy to be used when the sun is not shining. It will help meet the nation’s goal of making solar energy fully cost-competitive with other energy sources by the end of the decade. Worldwide, CSP activity is rapidly scaling, with approximately 10 gigawatts (GW) in various stages of operation or development. In the United States alone, nearly 2 GW of CSP are in operation.

  4. Antibubbles and fine cylindrical sheets of air

    NARCIS (Netherlands)

    Beilharz, D.; Guyon, A.; Li, E.Q.; Thoraval, Marie-Jean; Thoroddsen, S.T.

    2015-01-01

    Drops impacting at low velocities onto a pool surface can stretch out thin hemispherical sheets of air between the drop and the pool. These air sheets can remain intact until they reach submicron thicknesses, at which point they rupture to form a myriad of microbubbles. By impacting a

  5. Molding cork sheets to complex shapes

    Science.gov (United States)

    Sharpe, M. H.; Simpson, W. G.; Walker, H. M.

    1977-01-01

    Partially cured cork sheet is easily formed to complex shapes and then final-cured. Temperature and pressure levels required for process depend upon resin system used and final density and strength desired. Sheet can be bonded to surface during final cure, or can be first-formed in mold and bonded to surface in separate step.

  6. Fact Sheets on Pesticides in Schools.

    Science.gov (United States)

    National Coalition against the Misuse of Pesticides, Washington, DC.

    This document consists of a collection of fact sheets about the use of pesticides in schools and how to reduce it. The sheets are: (1) "Alternatives to Using Pesticides in Schools: What Is Integrated Pest Management?"; (2) "Health Effects of 48 Commonly Used Pesticides in Schools"; (3) "The Schooling of State Pesticide Laws--2002 Update: A Review…

  7. Clouds enhance Greenland ice sheet meltwater runoff

    NARCIS (Netherlands)

    Van Tricht, K.; Lhermitte, S.; Lenaerts, J. T M|info:eu-repo/dai/nl/314850163; Gorodetskaya, I. V.; L'Ecuyer, T. S.; Noël, B.|info:eu-repo/dai/nl/370612345; Van Den Broeke, M. R.|info:eu-repo/dai/nl/073765643; Turner, D. D.; Van Lipzig, N. P M

    2016-01-01

    The Greenland ice sheet has become one of the main contributors to global sea level rise, predominantly through increased meltwater runoff. The main drivers of Greenland ice sheet runoff, however, remain poorly understood. Here we show that clouds enhance meltwater runoff by about one-third relative

  8. 16 CFR 460.13 - Fact sheets.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Fact sheets. 460.13 Section 460.13 Commercial Practices FEDERAL TRADE COMMISSION TRADE REGULATION RULES LABELING AND ADVERTISING OF HOME INSULATION § 460.13 Fact sheets. If you are a manufacturer, you must give retailers and installers...

  9. Dylan Pritchett, Storyteller. Cue Sheet for Students.

    Science.gov (United States)

    Evans, Karen L. B.

    Designed to be used before and after attending a storytelling performance by Dylan Pritchett, this cue sheet presents information about the performance and suggests activities that can be done with classmates, friends, or family members. The cue sheet discusses where and why people tell stories, what makes a story good for telling, what makes a…

  10. Balance velocities of the Greenland ice sheet

    DEFF Research Database (Denmark)

    Joughin, I.; Fahnestock, M.; Ekholm, Simon;

    1997-01-01

    We present a map of balance velocities for the Greenland ice sheet. The resolution of the underlying DEM, which was derived primarily from radar altimetery data, yields far greater detail than earlier balance velocity estimates for Greenland. The velocity contours reveal in striking detail......, the balance map is useful for ice-sheet modelling, mass balance studies, and field planning....

  11. Steel Sheet Pile Walls in Soft Soil

    NARCIS (Netherlands)

    Kort, D.A.

    2002-01-01

    For almost a century, steel sheet pile walls are applied worldwide as earth retaining structures for excavations and quay walls. Within the framework of the development of European structural codes for Civil Engineering works, the Eurocodes, Eurocode 3 Part 5 for design of steel sheet pile walls was

  12. Clouds enhance Greenland ice sheet meltwater runoff

    NARCIS (Netherlands)

    Van Tricht, K.; Lhermitte, S.; Lenaerts, J. T M|info:eu-repo/dai/nl/314850163; Gorodetskaya, I. V.; L'Ecuyer, T. S.; Noël, B.|info:eu-repo/dai/nl/370612345; Van Den Broeke, M. R.|info:eu-repo/dai/nl/073765643; Turner, D. D.; Van Lipzig, N. P M

    2016-01-01

    The Greenland ice sheet has become one of the main contributors to global sea level rise, predominantly through increased meltwater runoff. The main drivers of Greenland ice sheet runoff, however, remain poorly understood. Here we show that clouds enhance meltwater runoff by about one-third relative

  13. Some plasma aspects and plasma diagnostics of ion sources.

    Science.gov (United States)

    Wiesemann, Klaus

    2008-02-01

    We consider plasma properties in the most advanced type of plasma ion sources, electron cyclotron resonance ion sources for highly charged ions. Depending on the operation conditions the plasma in these sources may be highly ionized, which completely changes its transport properties. The most striking difference to weakly ionized plasma is that diffusion will become intrinsically ambipolar. We further discuss means of plasma diagnostics. As noninvasive diagnostic methods we will discuss analysis of the ion beam, optical spectroscopy, and measurement of the x-ray bremsstrahlung continuum. From beam analysis and optical spectroscopy one may deduce ion densities, and electron densities and distribution functions as a mean over the line of sight along the axis (optical spectroscopy) or at the plasma edge (ion beam). From x-ray spectra one obtains information about the population of highly energetic electrons and the energy transfer from the driving electromagnetic waves to the plasma -- basic data for plasma modeling.

  14. Nuclear Data Sheets for A = 42

    Science.gov (United States)

    Chen, Jun; Singh, Balraj

    2016-07-01

    The experimental data are evaluated for known nuclides of mass number A = 42 (Al, Si, P, S, Cl, Ar, K, Ca, Sc, Ti, V, Cr). Detailed evaluated level properties and related information are presented, including adopted values of level and γ-ray energies, decay data (energies, intensities and placement of radiations), and other spectroscopic data. This work supersedes earlier full evaluations of A = 42 published by B. Singh, J.A. Cameron - Nucl.Data Sheets 92, 1 (2001) and P.M. Endt - Nucl. Phys. A521, 1 (1990); Errata and Addenda Nucl. Phys. A529, 763 (1991); Errata Nucl. Phys. A564, 609 (1993) (also P.M. Endt - Nucl. Phys. A633, 1 (1998) update). No excited states are known in 42Al, 42P, 42V and 42Cr, and structure information for 42Si and 42S is quite limited. There are no decay schemes available for the decay of 42Al, 42Si, 42P, 42V and 42Cr, while the decay schemes of 42Cl and 42Ti are incomplete in view of scarcity of data, and large gap between their Q-values and the highest energy levels populated in corresponding daughter nuclei. Structures of 42Ca, 42K, 42Sc and 42Ar nuclides remain the most extensively studied via many different nuclear reactions and decays.

  15. The Elementary Marine Ice Sheet Model (EMISM)

    Science.gov (United States)

    Pattyn, Frank

    2015-04-01

    Ice sheet models become more and more components of global climate system modelling instead of stand-alone features to study cryospheric processes. Full coupling of ice sheet models to atmospheric and ocean models requires a standard for ice sheet models, and more precisely for marine ice sheet models, where complex feedbacks between ice and ocean, such as marine ice sheet instability, and the atmosphere, such as the elevation-mass balance feedback, operate at different time scales. Recent model intercomparisons (e.g., SeaRISE, MISMIP) have shown that basic requirements for marine ice sheet models are still lacking and that the complexity of many ice sheet models is focused on processes that are either not well captured numerically (spatial resolution issue) or are of secondary importance compared to the essential features of marine ice sheet dynamics. Here, we propose a new and fast computing ice sheet model, devoid of most complexity, but capturing the essential feedbacks when coupled to ocean or atmospheric models. Its computational efficiency guarantees to easily tests its advantages as well as limits through ensemble modelling. EMISM (Elementary Marine Ice Sheet Model) is a vertically integrated ice sheet model based on the Shallow-Ice Approximation extended a Weertman sliding law. Although vertically integrated, thermomechanical coupling is ensured through a simplified representation of ice sheet thermodynamics based on an analytical solution of the vertical temperature profile, enhanced with strain heating. The marine boundary is represented by a parameterized flux condition similar to Pollard & Deconto (2012), based on Schoof (2007). A simplified ice shelf is added to account for buttressing of ice shelves in this parameterization. The ice sheet model is solved on a finite difference grid and special care is taken to its numerical efficiency and stability. While such model has a series of (known) deficiencies with respect to short time effects, its overall

  16. Histological staging and determination of the plasma 17 [beta]-estradiol, testosterone, and vitellogenin concentrations in white suckers (Catostomus commersoni) from distinct population segment rivers in Maine

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report describes the methods and results of the analyses of reproductive biomarkers in the white sucker collected from Distinct Population Segment (DPS)...

  17. Tantalum Sheet for Superconductor Diffusion Barrier Applications

    Science.gov (United States)

    Mathaudhu, S. N.; Hartwig, K. T.; Barber, R. E.; Pyon, T.

    2006-03-01

    This report presents preliminary results of a project with the aim to fabricate fine-grained tantalum sheet having a uniform microstructure that co-deforms well with pure copper for superconductor diffusion barrier applications. Multi-pass equal channel angular extrusion (ECAE) was used to refine the microstructure of 25 mm square cross-section bars of Ta; rolling was used to convert the bars to 0.38 mm thick sheet. Cu-Ta co-deformation characteristics were evaluated by assembling and drawing experimental Cu-Ta composite wires, containing the ECAE processed sheets, to 0.83 mm diameter and metallographically examining the thinned 2-4 micron Ta layer. The ECAE processed Ta sheet co-deformed well with Cu, and was found to have a smaller recrystallized grain size, a narrower grain size distribution and a slightly higher hardness compared to commercial diffusion barrier grade Ta sheet. The favorable results encourage further work.

  18. Plasma convection in the magnetotail lobes: statistical results from Cluster EDI measurements

    Directory of Open Access Journals (Sweden)

    S. Haaland

    2008-08-01

    Full Text Available A major part of the plasma in the Earth's magnetotail is populated through transport of plasma from the solar wind via the magnetotail lobes. In this paper, we present a statistical study of plasma convection in the lobes for different directions of the interplanetary magnetic field and for different geomagnetic disturbance levels. The data set used in this study consists of roughly 340 000 one-minute vector measurements of the plasma convection from the Cluster Electron Drift Instrument (EDI obtained during the period February 2001 to June 2007. The results show that both convection magnitude and direction are largely controlled by the interplanetary magnetic field (IMF. For a southward IMF, there is a strong convection towards the central plasma sheet with convection velocities around 10 km s−1. During periods of northward IMF, the lobe convection is almost stagnant. A By dominated IMF causes a rotation of the convection patterns in the tail with an oppositely directed dawn-dusk component of the convection for the northern and southern lobe. Our results also show that there is an overall persistent duskward component, which is most likely a result of conductivity gradients in the footpoints of the magnetic field lines in the ionosphere.

  19. Measurement of ion velocity profiles in a magnetic reconnection layer via current sheet jogging

    Science.gov (United States)

    Stein, G.; Yoo, J.; Yamada, M.; Ji, H.; Dorfman, S.; Lawrence, E.; Myers, C.; Tharp, T.

    2011-10-01

    In many laboratory plasmas, constructing stationary Langmuir and Mach probe arrays with resolution on the order of electron skin depth is technically difficult, and can introduce significant plasma perturbations. However, complete two- dimensional profiles of plasma density, electron temperature, and ion flow are important for studying the transfer of energy from magnetic fields to particles during magnetic reconnection. Through the use of extra ``Shaping Field'' coils in the Magnetic Reconnection Experiment (MRX) at the Princeton Plasma Physics Laboratory, the inward motion of the current sheet in the reconnection layer can be accelerated, or ``jogged,'' allowing the measurement of different points across the sheet with stationary probes. By acquiring data from Langmuir probes and Mach probes at different locations in the MRX with respect to the current sheet center, profiles of electron density and temperature and a vector plot of two-dimensional ion velocity in the plane of reconnection are created. Results from probe measurements will be presented and compared to profiles generated from computer simulation.

  20. Global properties of magnetotail current sheet flapping: THEMIS perspectives

    Directory of Open Access Journals (Sweden)

    A. Runov

    2009-01-01

    Full Text Available A sequence of magnetic field oscillations with an amplitude of up to 30 nT and a time scale of 30 min was detected by four of the five THEMIS spacecraft in the magnetotail plasma sheet. The probes P1 and P2 were at X=−15.2 and −12.7 RE and P3 and P4 were at X=−7.9 RE. All four probes were at −6.5>Y>−7.5 RE (major conjunction. Multi-point timing analysis of the magnetic field variations shows that fronts of the oscillations propagated flankward (dawnward and Earthward nearly perpendicular to the direction of the magnetic maximum variation (B1 at velocities of 20–30 km/s. These are typical characteristics of current sheet flapping motion. The observed anti-correlation between ∂B1/∂t and the Z-component of the bulk velocity make it possible to estimate a flapping amplitude of 1 to 3 RE. The cross-tail scale wave-length was found to be about 5 RE. Thus the flapping waves are steep tail-aligned structures with a lengthwise scale of >10 RE. The intermittent plasma motion with the cross-tail velocity component changing its sign, observed during flapping, indicates that the flapping waves were propagating through the ambient plasma. Simultaneous observations of the magnetic field variations by THEMIS ground-based magnetometers show that the flapping oscillations were observed during the growth phase of a substorm.

  1. Dusty plasmas

    Energy Technology Data Exchange (ETDEWEB)

    Fortov, Vladimir E; Khrapak, Aleksei G; Molotkov, Vladimir I; Petrov, Oleg F [Institute for High Energy Densities, Associated Institute for High Temperatures, Russian Academy of Sciences, Moscow (Russian Federation); Khrapak, Sergei A [Max-Planck-Institut fur Extraterrestrische Physik, Garching (Germany)

    2004-05-31

    The properties of dusty plasmas - low-temperature plasmas containing charged macroparticles - are considered. The most important elementary processes in dusty plasmas and the forces acting on dust particles are investigated. The results of experimental and theoretical investigations of different states of strongly nonideal dusty plasmas - crystal-like, liquid-like, gas-like - are summarized. Waves and oscillations in dusty plasmas, as well as their damping and instability mechanisms, are studied. Some results on dusty plasma investigated under microgravity conditions are presented. New directions of experimental research and potential applications of dusty plasmas are discussed. (reviews of topical problems)

  2. Vitamin B-6 and colorectal cancer risk: a prospective population-based study using 3 distinct plasma markers of vitamin B-6 status.

    Science.gov (United States)

    Gylling, Björn; Myte, Robin; Schneede, Jörn; Hallmans, Göran; Häggström, Jenny; Johansson, Ingegerd; Ulvik, Arve; Ueland, Per M; Van Guelpen, Bethany; Palmqvist, Richard

    2017-03-08

    Background: Higher plasma concentrations of the vitamin B-6 marker pyridoxal 5'-phosphate (PLP) have been associated with reduced colorectal cancer (CRC) risk. Inflammatory processes, including vitamin B-6 catabolism, could explain such findings.Objective: We investigated 3 biomarkers of vitamin B-6 status in relation to CRC risk.Design: This was a prospective case-control study of 613 CRC cases and 1190 matched controls nested within the Northern Sweden Health and Disease Study (n = 114,679). Participants were followed from 1985 to 2009, and the median follow-up from baseline to CRC diagnosis was 8.2 y. PLP, pyridoxal, pyridoxic acid (PA), 3-hydroxykynurenine, and xanthurenic acids (XAs) were measured in plasma with the use of liquid chromatography-tandem mass spectrometry. We calculated relative and absolute risks of CRC for PLP and the ratios 3-hydroxykynurenine:XA (HK:XA), an inverse marker of functional vitamin B-6 status, and PA:(PLP + pyridoxal) (PAr), a marker of inflammation and oxidative stress and an inverse marker of vitamin B-6 status.Results: Plasma PLP concentrations were associated with a reduced CRC risk for the third compared with the first quartile and for PLP sufficiency compared with deficiency [OR: 0.60 (95% CI: 0.44, 0.81) and OR: 0.55 (95% CI: 0.37, 0.81), respectively]. HK:XA and PAr were both associated with increased CRC risk [OR: 1.48 (95% CI: 1.08, 2.02) and OR: 1.50 (95% CI: 1.10, 2.04), respectively] for the fourth compared with the first quartile. For HK:XA and PAr, the findings were mainly observed in study participants with B-6 deficiency as measured by plasma PLP is associated with a clear increase in CRC risk. Furthermore, our analyses of novel markers of functional vitamin B-6 status and vitamin B-6-associated oxidative stress and inflammation suggest a role in tumor progression rather than initiation.

  3. Numerical study of magnetic reconnection process near in- terplanetary current sheet

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The third order accurate upwind compact difference scheme has been applied to the numerical study of the magnetic reconnection process possibly occurring near the interplanetary current sheet, under the framework of the two-dimensional compressible magnetohydrodynamics (MHD). Our results here show that the driven reconnection near the current sheet can occur within 10-30 min for the interplanetary high magnetic Reynolds number, RM =2 000-10 000, the stable magnetic reconnection structure can be formed in hour-order of magnitude, and there are some ba- sic properties such as the multiple X-line reconnections, vortical velocity structures, filament current systems, split-ting and collapse of the high-density plasma bulk. These results are helpful in understanding and identifying the magnetic reconnection phenomena near the interplanetary current sheets.

  4. "Ideally" unstable current sheets and the triggering of fast magnetic reconnection

    CERN Document Server

    Tenerani, Anna; Pucci, Fulvia; Landi, Simone; Rappazzo, Antonio Franco

    2016-01-01

    Magnetic reconnection is thought to be the dynamical mechanism underlying many explosive phenomena observed both in space and in the laboratory, though the question of how fast magnetic reconnection is triggered in such high Lundquist ($S$) number plasmas has remained elusive. It has been well established that reconnection can develop over timescales faster than those predicted traditionally once kinetic scales are reached. It has also been shown that, within the framework of resistive Magnetohydrodynamics (MHD), fast reconnection is achieved for thin enough sheets via the onset of the so-called plasmoid instability. The latter was discovered in studies specifically devoted to the Sweet-Parker current sheet, either as an initial condition or an apparent transient state developing in nonlinear studies. On the other hand, a fast tearing instability can grow on an ideal, i.e., $S$-independent, timescale (dubbed "ideal" tearing) within current sheets whose aspect ratio scales with the macroscopic Lundquist number...

  5. Synthesis of carbon fibers with branched nanographene sheets for electrochemical double layer capacitor application.

    Science.gov (United States)

    Matsushima, Masahiro; Kalita, Golap; Kato, Kimitoshi; Noda, Mikio; Uchida, Hideo; Wakita, Koichi; Umeno, Masayoshi; Tanemura, Masaki

    2014-03-01

    We demonstrate a one step technique to synthesis the carbon fibers (CNFs) with branched nanographene sheets by the pulsed discharge (PD) plasma chemical vapor deposition (CVD) process. Highly crystalline branched nanographene sheets were directly grown from the surface of the carbon fibers to obtain a three dimensional (3D) nanostructure. The growth process can be explained from the catalyst support growth of the CNFs, and subsequently nucleation and growth of the nanographene sheets from the crystalline surface of the CNF. The deposited nanostructured films with different pulse discharge were used as an electrode for electrochemical double-layer capacitors (EDLC). It is observed that the capacitance is dependent on the morphology of the electrode materials and an optimum capacitance is obtained with the branched nanographene on CNFs.

  6. Folded Sheet Versus Transparent Sheet Models for Human Symmetry Judgments

    Directory of Open Access Journals (Sweden)

    Jacques Ninio

    2011-07-01

    Full Text Available As a contribution to the mysteries of human symmetry perception, reaction time data were collected on the detection of symmetry or repetition violations, in the context of short term visual memory studies. The histograms for reaction time distributions are rather narrow in the case of symmetry judgments. Their analysis was performed in terms of a simple kinetic model of a mental process in two steps, a slow one for the construction of the representation of the images to be compared, and a fast one, in the 50 ms range, for the decision. There was no need for an additional ‘mental rotation’ step. Symmetry seems to facilitate the construction step. I also present here original stimuli showing a color equalization effect across a symmetry axis, and its counterpart in periodic patterns. According to a “folded sheet model”, when a shape is perceived, the brain automatically constructs a mirror-image representation of the shape. Based in part on the reaction time analysis, I present here an alternative “transparent sheet” model in which the brain constructs a single representation, which can be accessed from two sides, thus generating simultaneously a pattern and its mirror-symmetric partner. Filtering processes, implied by current models of symmetry perception could intervene at an early stage, by nucleating the propagation of similar perceptual groupings in the two symmetric images.

  7. Determination of MBL Gene by Using PCR-RFLP and the Study on the Association of Plasma Concentrations of Mannose Binding Protein in Healthy Individuals of Han and Mongolian Population

    Institute of Scientific and Technical Information of China (English)

    贾天军; 李萍; 张庶民; 刘洁; 赵铁军; 张进顺; 雷殿良; 翟登高; 李河民

    2004-01-01

    The aim of this study was to analyze the point mutation of the exon 1 at codon 54 of the mannose ( or mannan)-binding lectin (MBL) gene in healthy individuals of Chinese Hans and Mongolian population, and to find out any association between the plasma levels of MBL and the gene mutation frequency in beth groups of individuals. Blood samples were collected randomly from 56 healthy individuals of Chinese Hans and 37 Mongolian. The detection of the point mutations of the MBL gene was performed by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and detections for plasma levels of MBL were determined by using MBL ELISA kits. A MBL PCR method of assay was established with high specificity, and good reproducibility. By optimizing the PCR condition, the optimal annealing temperature was 55℃, and the lowest detec-tion limit was 160 pg. No bands were found in non-specificity samples (HAV, HBV, HCV and TB), and the sequences of PCR products were the same as the expected ones. Also a MBL PCR-RFIP was established. Upon electrophoresis of the digested products in 3% agarose gel, there were 3 patterns: in which 2 bands correspond to molecule weight 232 bp and 93 bp;1 band, corresponds to molecule weight 325 bp and 3 bands correspond to molecule weight 325 bp, 232 bp and 93 bp, respectively. Three bands of 325 bp, 232 bp and 93 bp of point mutations were found at cedon 54 of MBL ceding gene. Frequencies in healthy Han and Mongolian population were 0. 2321 and 0. 1757 respectively. The average plasma MBL concentration was 1998.750μg/L, with SD of 1505. 152 in 56 healthy Han population and 2525.676μg/L, with SD of 1955. 188 in 37 Mongolian. A negative correlation between MBL concentration and gene mutation frequency was found in healthy Han population. Frequency of point mutation was 1.00 when the MBL concentrations were below 100μg/L; frequency of point mutation was0.4524 when the concentration was 100μg/L to 1000μg/L; and the frequency of point

  8. The Association of Ideal Cardiovascular Health and Atherogenic Index of Plasma in Rural Population: A Cross-Sectional Study from Northeast China

    Science.gov (United States)

    Chang, Ye; Li, Yuan; Guo, Xiaofan; Dai, Dongxue; Sun, Yingxian

    2016-01-01

    In 2010, the American Heart Association has proposed a new concept “ideal cardiovascular health” (CVH) based on seven CVH metrics: smoking, body mass index, physical activity, diet score, total cholesterol, blood pressure, and fasting plasma glucose. We aimed to determine the association of CVH with atherogenic index of plasma (AIP), a strong marker for atherosclerosis (AS). This cross-sectional study was conducted in the rural areas of northeast China and 11,113 middle-aged subjects were enrolled. Seven CVH metrics were classified into ideal, intermediate, and poor groups. AIP was calculated as log (TG/HDL) (triglycerides/high-density lipoprotein cholesterol). AIP > 0.21 was classified into the high AIP group and served as dependent variable. All seven CVH metrics were correlated with AIP. A gradient relationship between the number of poor CVH metrics and the prevalence of high AIP existed. Log binomial regression analysis showed that compared to those with five to seven ideal CVH metrics, individuals with four, three, two, one, and no ideal CVH metrics had 1.67, 2.66, 4.00, 5.30 and 6.50 times higher prevalence for high AIP. The subjects with poor CVH status had 2.73 times higher prevalence for high AIP. We found an inversely gradient relationship between the number of ideal CVH metrics and lower prevalence of high AIP. PMID:27775583

  9. Process characteristics of fibre-laser-assisted plasma arc welding

    OpenAIRE

    Mahrle, A; SCHNICK, M; Rose, S; Demuth, C; Beyer, E.; Füssel, U

    2011-01-01

    Abstract Experimental and theoretical investigations on fibre-laser assisted plasma arc welding (LAPW) have been performed. Welding experiments were carried out on aluminium and steel sheets. In case of a highly focused laser beam and a separate arrangement of plasma torch and laser beam, high-speed video recordings of the plasma arc and corresponding measurements of the time-dependent arc voltage revealed differences in the process behaviour for both materials. In case of aluminium weldin...

  10. Flexible Structural-Health-Monitoring Sheets

    Science.gov (United States)

    Qing, Xinlin; Kuo, Fuo

    2008-01-01

    A generic design for a type of flexible structural-health-monitoring sheet with multiple sensor/actuator types and a method of manufacturing such sheets has been developed. A sheet of this type contains an array of sensing and/or actuation elements, associated wires, and any other associated circuit elements incorporated into various flexible layers on a thin, flexible substrate. The sheet can be affixed to a structure so that the array of sensing and/or actuation elements can be used to analyze the structure in accordance with structural-health-monitoring techniques. Alternatively, the sheet can be designed to be incorporated into the body of the structure, especially if the structure is made of a composite material. Customarily, structural-health monitoring is accomplished by use of sensors and actuators arrayed at various locations on a structure. In contrast, a sheet of the present type can contain an entire sensor/actuator array, making it unnecessary to install each sensor and actuator individually on or in a structure. Sensors of different types such as piezoelectric and fiber-optic can be embedded in the sheet to form a hybrid sensor network. Similarly, the traces for electric communication can be deposited on one or two layers as required, and an entirely separate layer can be employed to shield the sensor elements and traces.

  11. Computer-aided light sheet flow visualization

    Science.gov (United States)

    Stacy, Kathryn; Severance, Kurt; Childers, Brooks A.

    1993-01-01

    A computer-aided flow visualization process has been developed to analyze video images acquired from rotating and translating light sheet visualization systems. The computer process integrates a mathematical model for image reconstruction, advanced computer graphics concepts, and digital image processing to provide a quantitative and visual analysis capability. The image reconstruction model, based on photogrammetry, uses knowledge of the camera and light sheet locations and orientations to project two-dimensional light sheet video images into three-dimensional space. A sophisticated computer visualization package, commonly used to analyze computational fluid dynamics (CFD) data sets, was chosen to interactively display the reconstructed light sheet images, along with the numerical surface geometry for the model or aircraft under study. A description is provided of the photogrammetric reconstruction technique, and the image processing and computer graphics techniques and equipment. Results of the computer aided process applied to both a wind tunnel translating light sheet experiment and an in-flight rotating light sheet experiment are presented. The capability to compare reconstructed experimental light sheet images and CFD solutions in the same graphics environment is also demonstrated.

  12. Origin of the warped heliospheric current sheet

    Energy Technology Data Exchange (ETDEWEB)

    Wilcox, J.M.; Hoeksema, J.T.; Scherrer, P.H.

    1980-08-01

    The warped heliospheric current sheet for early 1976 is calculated from the observed photospheric magnetic field by a potential field method. Comparisons with measurements of the interplanetary magnetic field polarity for early 1976 obtained at several locations in the heliosphere by Helios 1, Helios 2, Pioneer 11, and at the earth show a rather detailed agreement between the computed current sheet and the observations. It appears that the large-scale structure of the warped heliospheric current sheet is determined by the structure of the photospheric magnetic field and that ballerina skirt effects may add small-scale ripples.

  13. Origin of the warped heliospheric current sheet

    Science.gov (United States)

    Wilcox, J. M.; Hoeksema, J. T.; Scherrer, P. H.

    1980-08-01

    The warped heliospheric current sheet for early 1976 is calculated from the observed photospheric magnetic field by a potential field method. Comparisons with measurements of the interplanetary magnetic field polarity for early 1976 obtained at several locations in the heliosphere by Helios 1, Helios 2, Pioneer 11, and at the earth show a rather detailed agreement between the computed current sheet and the observations. It appears that the large-scale structure of the warped heliospheric current sheet is determined by the structure of the photospheric magnetic field and that 'ballerina skirt' effects may add small scale ripples.

  14. Bifurcation of Jovian magnetotail current sheet

    Directory of Open Access Journals (Sweden)

    P. L. Israelevich

    2006-07-01

    Full Text Available Multiple crossings of the magnetotail current sheet by a single spacecraft give the possibility to distinguish between two types of electric current density distribution: single-peaked (Harris type current layer and double-peaked (bifurcated current sheet. Magnetic field measurements in the Jovian magnetic tail by Voyager-2 reveal bifurcation of the tail current sheet. The electric current density possesses a minimum at the point of the Bx-component reversal and two maxima at the distance where the magnetic field strength reaches 50% of its value in the tail lobe.

  15. Dynamics of laterally confined marine ice sheets

    OpenAIRE

    Kowal, Katarzyna N.; Pegler, Samuel S.; Worster, M. Grae

    2016-01-01

    This is the author accepted manuscript. The final version is available from Cambridge University Press via http://dx.doi.org/10.1017/jfm.2016.37 We present an experimental and theoretical study of the dynamics of laterally confined marine ice sheets in the natural limit in which the long, narrow channel into which they flow is wider than the depth of the ice. A marine ice sheet comprises a grounded ice sheet in contact with bedrock that floats away from the bedrock at a ‘grounding line’ t...

  16. Photobiology Research Laboratory (Fact Sheet)

    Energy Technology Data Exchange (ETDEWEB)

    2012-06-01

    This fact sheet provides information about Photobiology Research Laboratory capabilities and applications at NREL. The photobiology group's research is in four main areas: (1) Comprehensive studies of fuel-producing photosynthetic, fermentative, and chemolithotrophic model microorganisms; (2) Characterization and engineering of redox enzymes and proteins for fuel production; (3) Genetic and pathway engineering of model organisms to improve production of hydrogen and hydrocarbon fuels; and (4) Studies of nanosystems using biological and non-biological materials in hybrid generation. NREL's photobiology research capabilities include: (1) Controlled and automated photobioreactors and fermenters for growing microorganisms under a variety of environmental conditions; (2) High-and medium-throughput screening of H{sub 2}-producing organisms; (3) Homologous and heterologous expression, purification, and biochemical/biophysical characterization of redox enzymes and proteins; (4) Qualitative and quantitative analyses of gases, metabolites, carbohydrates, lipids, and proteins; (5) Genetic and pathway engineering and development of novel genetic toolboxes; and (6) Design and spectroscopic characterization of enzyme-based biofuel cells and energy conversion nanodevices.

  17. Reconnection at three dimensional magnetic null points: Effect of current sheet asymmetry

    Science.gov (United States)

    Wyper, P. F.; Jain, Rekha

    2013-05-01

    Asymmetric current sheets are likely to be prevalent in both astrophysical and laboratory plasmas with complex three dimensional (3D) magnetic topologies. This work presents kinematic analytical models for spine and fan reconnection at a radially symmetric 3D null (i.e., a null where the eigenvalues associated with the fan plane are equal) with asymmetric current sheets. Asymmetric fan reconnection is characterized by an asymmetric reconnection of flux past each spine line and a bulk flow of plasma across the null point. In contrast, asymmetric spine reconnection is characterized by the reconnection of an equal quantity of flux across the fan plane in both directions. The higher modes of spine reconnection also include localized wedges of vortical flux transport in each half of the fan. In this situation, two definitions for reconnection rate become appropriate: a local reconnection rate quantifying how much flux is genuinely reconnected across the fan plane and a global rate associated with the net flux driven across each semi-plane. Through a scaling analysis, it is shown that when the ohmic dissipation in the layer is assumed to be constant, the increase in the local rate bleeds from the global rate as the sheet deformation is increased. Both models suggest that asymmetry in the current sheet dimensions will have a profound effect on the reconnection rate and manner of flux transport in reconnection involving 3D nulls.

  18. Reconnection at three dimensional magnetic null points: Effect of current sheet asymmetry

    Energy Technology Data Exchange (ETDEWEB)

    Wyper, P. F.; Jain, Rekha [School of Mathematics and Statistics, University of Sheffield, Sheffield, South Yorkshire S3 7RH (United Kingdom)

    2013-05-15

    Asymmetric current sheets are likely to be prevalent in both astrophysical and laboratory plasmas with complex three dimensional (3D) magnetic topologies. This work presents kinematic analytical models for spine and fan reconnection at a radially symmetric 3D null (i.e., a null where the eigenvalues associated with the fan plane are equal) with asymmetric current sheets. Asymmetric fan reconnection is characterized by an asymmetric reconnection of flux past each spine line and a bulk flow of plasma across the null point. In contrast, asymmetric spine reconnection is characterized by the reconnection of an equal quantity of flux across the fan plane in both directions. The higher modes of spine reconnection also include localized wedges of vortical flux transport in each half of the fan. In this situation, two definitions for reconnection rate become appropriate: a local reconnection rate quantifying how much flux is genuinely reconnected across the fan plane and a global rate associated with the net flux driven across each semi-plane. Through a scaling analysis, it is shown that when the ohmic dissipation in the layer is assumed to be constant, the increase in the local rate bleeds from the global rate as the sheet deformation is increased. Both models suggest that asymmetry in the current sheet dimensions will have a profound effect on the reconnection rate and manner of flux transport in reconnection involving 3D nulls.

  19. Properties of current sheet thinning at x ˜- 10 to -12 RE

    Science.gov (United States)

    Artemyev, A. V.; Angelopoulos, V.; Runov, A.; Petrokovich, A. A.

    2016-07-01

    We report on Time History of Events and Macroscale Interactions during Substorms (THEMIS) observations of current sheet thinning in Earth's magnetotail at around x =- 10 to -12 Earth radii. The THEMIS spacecraft configuration in October-December 2015 allows us to construct both gradients that contribute to the cross-tail current density jy=μ0-1(∂Bx/∂z-∂Bz/∂x) (GSM coordinates). For 17 events when the spacecraft observed a gradual Bz decrease and jy increase, we find the following average scaling relations: for the current density jy˜Bz-7/4, for the lobe magnetic field BL˜Bz-1/4, and for the plasma density ni˜Bz-3/4. We show that the temperature of ions and electrons decreases and the plasma pressure gradient ∂p/∂x rapidly increases during current sheet thinning. The scale Lx=(∂lnp/∂x)-1 decreases a few thousand kilometers. We also consider current carriers in thinning current sheets: both ion and electron current-dominated current sheets, preferentially located near dusk and midnight, respectively, are found.

  20. Plasma waves

    CERN Document Server

    Swanson, DG

    1989-01-01

    Plasma Waves discusses the basic development and equations for the many aspects of plasma waves. The book is organized into two major parts, examining both linear and nonlinear plasma waves in the eight chapters it encompasses. After briefly discussing the properties and applications of plasma wave, the book goes on examining the wave types in a cold, magnetized plasma and the general forms of the dispersion relation that characterize the waves and label the various types of solutions. Chapters 3 and 4 analyze the acoustic phenomena through the fluid model of plasma and the kinetic effects. Th

  1. Plasma astrophysics

    CERN Document Server

    Kaplan, S A; ter Haar, D

    2013-01-01

    Plasma Astrophysics is a translation from the Russian language; the topics discussed are based on lectures given by V.N. Tsytovich at several universities. The book describes the physics of the various phenomena and their mathematical formulation connected with plasma astrophysics. This book also explains the theory of the interaction of fast particles plasma, their radiation activities, as well as the plasma behavior when exposed to a very strong magnetic field. The text describes the nature of collective plasma processes and of plasma turbulence. One author explains the method of elementary

  2. Reconnection at 3D Magnetic Null Points: Effect of Current Sheet Asymmetry

    CERN Document Server

    Wyper, Peter F

    2013-01-01

    Asymmetric current sheets are likely to be prevalent in both astrophysical and laboratory plasmas with complex three dimensional (3D) magnetic topologies. This work presents kinematic analytical models for spine and fan reconnection at a symmetric 3D null with asymmetric current sheets. Asymmetric fan reconnection is characterized by an asymmetric reconnection of flux past each spine line and a bulk flow of plasma across the null point. In contrast, asymmetric spine reconnection is inherently equal and opposite in how flux is reconnected across the fan plane. The higher modes of spine reconnection also include localized wedges of vortical flux transport in each half of the fan. In this situation, two definitions for reconnection rate become appropriate: a local reconnection rate quantifying how much flux is genuinely reconnected across the fan plane and a global rate associated with the net flux driven across each semi-plane. Through a scaling analysis it is shown that when the ohmic dissipation in the layer ...

  3. Field reversing magnetotail current sheets: earth, Venus, and Comet Giacobini-Zinner

    Energy Technology Data Exchange (ETDEWEB)

    McComas, D.J.

    1986-09-01

    This dissertation examines the field reversing magnetotail current sheets at the earth, Venus, and Comet Giacobini-Zinner. In the near earth study a new analysis technique is developed to calculate the detailed current density distributions within the cross tail current sheet for the first time. This technique removes the effects of a variable sheet velocity by inverting intersatellite timings between the co-orbiting satellites ISEE-1 and -2. Case studies of three relatively geomagnetically quiet crossings are made; sheet thicknesses and peak current densities are approx.1-5 x 10/sup 4/ km and approx.5-50 nA/m/sup 2/. Current density distributions reveal a high density central region, lower density shoulders, and considerable fine structure throughout. In the Venus study another new analysis technique is developed to reconstruct the average tail configuration from a correlation between field magnitude and draping angle in a large statistical data set. In the comet study, high resolution magnetic field and plasma electron data from the ICE traversal of Giacobini-Zinner are combined for the first time to determine the tail/current sheet geometry and calculate certain important but unmeasured local ion and upstream properties. Pressure balance across the tail gives ion temperatures and betas of approx.1.2 x 10/sup 5/ K and approx.40 in the center of the current sheet to approx.1 x 10/sup 6/ K and approx.3 in the outer lobes. Axial stress balance shows that the velocity shear upstream near the nucleus is >6 (approx.1 at ICE), and that a region of strongly enhanced mass loading (ion source rate approx.24 times that upstream from lobes) exists upstream from the current sheet. The integrated downtail mass flux is approx.2.6 x 10/sup 26/ H/sub 2/O+/sec, which is only approx.1% of the independently determined total cometary efflux. 79 refs., 37 figs.

  4. The generation of rapid solar flare hard X-ray and microwave fluctuations in current sheets

    Science.gov (United States)

    Holman, Gordon D.

    The generation of rapid fluctuations, or spikes, in hard X-ray and microwave bursts via the disruption of electron heating and acceleration in current sheets is studied. It is found that 20 msec hard X-ray fluctuations can be thermally generated in a current sheet if the resistivity in the sheet is highly anomalous, the plasma density in the emitting region is relatively high, and the volume of the emitting region is greater than that of the current sheet. A specific mechanism for producing the fluctuations, involving heating in the presence of ion acoustic turbulence and a constant driving electric field, and interruption of the heating by a strong two-stream instability, is discussed. Variations upon this mechanism are also discussed. This mechanism also modulates electron acceleration, as required for the microwave spike emission. If the hard X-ray emission at energies less than approx. 1000 keV is nonthermal bremsstrahlung, the coherent modulation of electron acceleration in a large number of current sheets is required.

  5. More Fact Sheets - SEER Cancer Statistics

    Science.gov (United States)

    Cancer Statistical Fact Sheets are summaries of common cancer types developed to provide an overview of frequently-requested cancer statistics including incidence, mortality, survival, stage, prevalence, and lifetime risk.

  6. Nanotechnology for Site Remediation: Fact Sheet

    Science.gov (United States)

    This fact sheet presents a snapshot of nanotechnology and its current uses in remediation. It presents information to help site project managers understand the potential applications of this group of technologies at their sites.

  7. Federal Incentives for Wind Power (Fact Sheet)

    Energy Technology Data Exchange (ETDEWEB)

    2013-05-01

    This fact sheet describes the federal incentives available as of April 2013 that encourage increased development and deployment of wind energy technologies, including research grants, tax incentives, and loan programs.

  8. USFWS Wildlife Health Office Fact Sheet

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This fact sheet provides background information on the Wildlife Health Office, and contains information for reporting sick or dead animals.

  9. More Fact Sheets - SEER Cancer Statistics

    Science.gov (United States)

    Cancer Statistical Fact Sheets are summaries of common cancer types developed to provide an overview of frequently-requested cancer statistics including incidence, mortality, survival, stage, prevalence, and lifetime risk.

  10. Advancing Concentrating Solar Power Research (Fact Sheet)

    Energy Technology Data Exchange (ETDEWEB)

    2014-02-01

    Researchers at the National Renewable Energy Laboratory (NREL) provide scientific, engineering, and analytical expertise to help advance innovation in concentrating solar power (CSP). This fact sheet summarizes how NREL is advancing CSP research.

  11. Energy Systems Integration: NREL + Solectria (Fact Sheet)

    Energy Technology Data Exchange (ETDEWEB)

    2015-02-01

    This fact sheet describes the collaboration between NREL and Solectria at the Energy Systems Integration Facility (ESIF) to to develop 500- and 750-kilowatt photovoltaic (PV) inverters with advanced features that can support the electric grid.

  12. Collector/Receiver Characterization (Fact Sheet)

    Energy Technology Data Exchange (ETDEWEB)

    2010-08-01

    Fact sheet describing NREL CSP Program capabilities for collector/receiver characterization: determining optical efficiency, measuring heat loss, developing and testing concentrators, concentrating the sun's power, and optically characterizing CSP plants.

  13. Greenland Radar Ice Sheet Thickness Measurements

    Data.gov (United States)

    National Aeronautics and Space Administration — Two 150-MHz coherent radar depth sounders were developed and flown over the Greenland ice sheet to obtain ice thickness measurements in support of PARCA...

  14. Formation of Saddle-Shaped Composite Sheets

    Science.gov (United States)

    Verdinsh, G.; Rocens, K.; Serdyuk, D.

    2000-11-01

    Based on the deformation model of an unbalanced multilayer composite, changes in bending curvatures of sheet-type composites with nonsymmetric structure relative to the midplane of the sheet, depending on the moisture of layers, are predicted. The bending curvatures of saddle-shaped sheets of wood-based composites are calculated with regard to the physical and mechanical properties, geometrical dimensions, orientation, and distribution of layers. The analytical results are compared with the bending curvatures found experimentally for a four-layered unbalanced composite made of birch veneer. The applied calculation model enables us to determine the values of bending curvatures of saddle-shaped wood composite sheets, which can be used in elaborating the technological recommendations.

  15. Comparing translational population-PBPK modelling of brain microdialysis with bottom-up prediction of brain-to-plasma distribution in rat and human.

    Science.gov (United States)

    Ball, Kathryn; Bouzom, François; Scherrmann, Jean-Michel; Walther, Bernard; Declèves, Xavier

    2014-11-01

    The prediction of brain extracellular fluid (ECF) concentrations in human is a potentially valuable asset during drug development as it can provide the pharmacokinetic input for pharmacokinetic-pharmacodynamic models. This study aimed to compare two translational modelling approaches that can be applied at the preclinical stage of development in order to simulate human brain ECF concentrations. A population-PBPK model of the central nervous system was developed based on brain microdialysis data, and the model parameters were translated to their corresponding human values to simulate ECF and brain tissue concentration profiles. In parallel, the PBPK modelling software Simcyp was used to simulate human brain tissue concentrations, via the bottom-up prediction of brain tissue distribution using two different sets of mechanistic tissue composition-based equations. The population-PBPK and bottom-up approaches gave similar predictions of total brain concentrations in both rat and human, while only the population-PBPK model was capable of accurately simulating the rat ECF concentrations. The choice of PBPK model must therefore depend on the purpose of the modelling exercise, the in vitro and in vivo data available and knowledge of the mechanisms governing the membrane permeability and distribution of the drug.

  16. Normal fasting plasma glucose levels and type 2 diabetes: the high-risk and population strategy for occupational health promotion (HIPOP-OHP) [corrected] study.

    Science.gov (United States)

    Hayashino, Y; Fukuhara, S; Suzukamo, Y; Okamura, T; Tanaka, T; Ueshima, H

    2007-09-01

    The objective of this study is to ascertain if higher normal fasting glucose levels are also an independent risk of developing diabetes in an Asian population, and we thus analysed data from a cohort of healthy Japanese workers. We used data from the non-randomised trial on health promotion intervention, High-risk and Population Strategy for Occupational Health Promotion (HIPOP-OHP) Study. Diabetes cases and those who had fasting blood glucose levels equal to or greater than 100 mg/dl at baseline were excluded, and the Cox proportional-hazards model was used for the analysis. During the four-year follow-up of 2212 participants, we found 37 diabetes cases. In the multivariable model, people with blood glucose levels in the 4th quartile had a higher risk of diabetes than those in the bottom quartile; the multivariable-adjusted odds ratio was 2.52. The risk of diabetes abruptly rose in persons with blood glucose levels higher than 94 mg/dl (fourth quartile). A significant linear trend was not observed in the 1st to 3rd quartiles (p=0.726). In conclusion, higher fasting glucose level was associated with the risk of diabetes, and we found a threshold in the association between fasting blood glucose levels and risk of diabetes in an Asian population.

  17. Catapult current sheet relaxation model confirmed by THEMIS observations

    Science.gov (United States)

    Machida, S.; Miyashita, Y.; Ieda, A.; Nose, M.; Angelopoulos, V.; McFadden, J. P.

    2014-12-01

    In this study, we show the result of superposed epoch analysis on the THEMIS probe data during the period from November, 2007 to April, 2009 by setting the origin of time axis to the substorm onset determined by Nishimura with THEMIS all sky imager (THEMS/ASI) data (http://www.atmos.ucla.edu/~toshi/files/paper/Toshi_THEMIS_GBO_list_distribution.xls). We confirmed the presence of earthward flows which can be associated with north-south auroral streamers during the substorm growth phase. At around X = -12 Earth radii (Re), the northward magnetic field and its elevation angle decreased markedly approximately 4 min before substorm onset. A northward magnetic-field increase associated with pre-onset earthward flows was found at around X = -17Re. This variation indicates the occurrence of the local depolarization. Interestingly, in the region earthwards of X = -18Re, earthward flows in the central plasma sheet (CPS) reduced significantly about 3min before substorm onset. However, the earthward flows enhanced again at t = -60 sec in the region around X = -14 Re, and they moved toward the Earth. At t = 0, the dipolarization of the magnetic field started at X ~ -10 Re, and simultaneously the magnetic reconnection started at X ~ -20 Re. Synthesizing these results, we can confirm the validity of our catapult current sheet relaxation model.

  18. Optical Studies of the Neutral Sheet Physics on MRX

    Science.gov (United States)

    Kuritsyn, A.; Ji, H.; Ren, Y.; Terry, S.; Yamada, M.; Levinton, F.

    2003-04-01

    Recent experiments on MRX have produced a lot of fundamental data on magnetic reconnection [1]. Nevertheless some key questions about the reconnection physics still remain unsolved such as the mechanism of the nonclassical ion heating and resistivity enhancement. To further improve our understanding of the structure of the neutral sheet and microscale processes accompanying reconnection the following non-perturbing optical diagnostics are being implemented: ion dynamics spectroscopy probe (IDSP) and planar laser induced fluorescence (PLIF). The IDSP is an insertable optical probe capable of measuring local ion temperature and flow velocities via Dopler spectroscopy. The PLIF imaging diagnostic is being developed on MRX to obtain the space and time resolved structure of the ion density fluctuations in the reconnection layer. There are some experimental indications and theoretical predictions that lower hybrid frequency electromagnetic fluctuations recently found in the current sheet can play significant role in the ion heating [2,3]. To verify this hypothesis we plan to do a systematic study, employing new diagnostics together with currently used fast Langmuir and magnetic pickup fluctuation probes, of the correlation between the ion temperature rise and fluctuations in the reconnection layer. MRX is jointly supported by DOE, NASA and NSF. [1] M. Yamada et al., Phys. Plasmas 4(5),1936(1997) [2] S. Ichimaru, J. Phys. Soc. Japan 39(5),1373(1975) [3] H. Ji et al., Bull. Am. Phys. Soc. 44,322(2002)

  19. Force focusing in confined fibres and sheets

    Energy Technology Data Exchange (ETDEWEB)

    Romero, Victor; Cerda, Enrique [Departamento de Fisica, Universidad de Santiago, Av. Ecuador 3493, Santiago (Chile); Witten, T A; Liang Tao [James Franck Institute, University of Chicago, Chicago IL 60637 (United States)], E-mail: t-witten@uchicago.edu

    2008-07-07

    A thin fibre or sheet curled into a circular container has a detached region whose shape and force ratios are independent of material properties and container radius. We compute this shape and compare it with experiments. The discrete forces acting at either end of the detached region have a ratio that depends only on the length of the fibre or sheet relative to the circle radius. We calculate this force ratio in three regimes of circle radius. (fast track communication)

  20. Electron-scale sheets of whistlers close to the magnetopause

    Directory of Open Access Journals (Sweden)

    G. Stenberg

    2005-12-01

    Full Text Available Whistler emissions close to the magnetopause on the magnetospheric side are investigated using the four Cluster spacecraft. The waves are found to be generated in thin (electron-scale sheets moving with the plasma drift velocity. A feature in the electron data coincides with the waves; hot magnetospheric electrons disappear for a few satellite spins. This produces or enhances a temperature anisotropy, which is found to be responsible for the generation of the whistler mode waves. The high energy electrons are thought to be lost through the magnetopause and we suggest that the field lines, on which the waves are generated, are directly connected to a reconnection diffusion region at the magnetopause.

  1. Magnetic guide field generation in collisionless current sheets

    Directory of Open Access Journals (Sweden)

    W. Baumjohann

    2010-03-01

    Full Text Available In thin (Δ< few λi collisionless current sheets in a space plasma like the magnetospheric tail or magnetopause current layer, magnetic fields can grow from thermal fluctuation level by the action of the non-magnetic Weibel instability (Weibel, 1959. The instability is driven by the counter-streaming electron inflow from the "ion diffusion" (ion inertial Hall region into the inner current (electron inertial region after thermalisation by the two-stream instability. Under magnetospheric tail conditions it takes ~50 e-folding times (~100 s for the Weibel field to reach observable amplitudes |bW|~1 nT. In counter-streaming inflows these fields are of guide field type.

  2. Fact sheet: Ethanol from corn

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-05-31

    This fact sheet is intended to provide an overview of the advantages of ethanol from corn, emphasizing ethanol`s contribution to environmental protection and sustainable agriculture. Ethanol, an alternative fuel used as an octane enhancer is produced through the conversion of starch to sugars by enzymes, and fermentation of these sugars to ethanol by yeast. The production process may involve wet milling or dry milling. Both these processes produce valuable by-products, in addition to ethanol and carbon dioxide. Ethanol contains about 32,000 BTU per litre. It is commonly believed that using state-of-the-art corn farming and corn processing processes, the amount of energy contained in ethanol and its by-products would be more than twice the energy required to grow and process corn into ethanol. Ethanol represents the third largest market for Ontario corn, after direct use as animal feed and wet milling for starch, corn sweetener and corn oil. The environmental consequences of using ethanol are very significant. It is estimated that a 10 per cent ethanol blend in gasoline would result in a 25 to 30 per cent decrease in carbon monoxide emissions, a 6 to 10 per cent decrease in net carbon dioxide, a slight increase in nitrous oxide emissions which, however, would still result in an overall decrease in ozone formation, since the significant reduction in carbon monoxide emissions would compensate for any slight increase in nitrous oxide. Volatile organic compounds emission would also decrease by about 7 per cent with a 10 per cent ethanol blend. High level blends could reduce VOCs production by as much as 30 per cent. 7 refs.

  3. Existence of three-dimensional ideal-magnetohydrodynamic equilibria with current sheets

    Energy Technology Data Exchange (ETDEWEB)

    Loizu, J. [Max-Planck-Institut für Plasmaphysik, D-17491 Greifswald (Germany); Princeton Plasma Physics Laboratory, PO Box 451, Princeton, New Jersey 08543 (United States); Hudson, S. R.; Bhattacharjee, A.; Lazerson, S. [Princeton Plasma Physics Laboratory, PO Box 451, Princeton, New Jersey 08543 (United States); Helander, P. [Max-Planck-Institut für Plasmaphysik, D-17491 Greifswald (Germany)

    2015-09-15

    We consider the linear and nonlinear ideal plasma response to a boundary perturbation in a screw pinch. We demonstrate that three-dimensional, ideal-MHD equilibria with continuously nested flux-surfaces and with discontinuous rotational-transform across the resonant rational-surfaces are well defined and can be computed both perturbatively and using fully nonlinear equilibrium calculations. This rescues the possibility of constructing MHD equilibria with current sheets and continuous, smooth pressure profiles. The results predict that, even if the plasma acts as a perfectly conducting fluid, a resonant magnetic perturbation can penetrate all the way into the center of a tokamak without being shielded at the resonant surface.

  4. Buckling Behavior of Substrate Supported Graphene Sheets

    Directory of Open Access Journals (Sweden)

    Kuijian Yang

    2016-01-01

    Full Text Available The buckling of graphene sheets on substrates can significantly degrade their performance in materials and devices. Therefore, a systematic investigation on the buckling behavior of monolayer graphene sheet/substrate systems is carried out in this paper by both molecular mechanics simulations and theoretical analysis. From 70 simulation cases of simple-supported graphene sheets with different sizes under uniaxial compression, two different buckling modes are investigated and revealed to be dominated by the graphene size. Especially, for graphene sheets with length larger than 3 nm and width larger than 1.1 nm, the buckling mode depends only on the length/width ratio. Besides, it is revealed that the existence of graphene substrate can increase the critical buckling stress and strain to 4.39 N/m and 1.58%, respectively, which are about 10 times those for free-standing graphene sheets. Moreover, for graphene sheets with common size (longer than 20 nm, both theoretical and simulation results show that the critical buckling stress and strain are dominated only by the adhesive interactions with substrate and independent of the graphene size. Results in this work provide valuable insight and guidelines for the design and application of graphene-derived materials and nano-electromechanical systems.

  5. Antibubbles and fine cylindrical sheets of air

    KAUST Repository

    Beilharz, D.

    2015-08-14

    Drops impacting at low velocities onto a pool surface can stretch out thin hemispherical sheets of air between the drop and the pool. These air sheets can remain intact until they reach submicron thicknesses, at which point they rupture to form a myriad of microbubbles. By impacting a higher-viscosity drop onto a lower-viscosity pool, we have explored new geometries of such air films. In this way we are able to maintain stable air layers which can wrap around the entire drop to form repeatable antibubbles, i.e. spherical air layers bounded by inner and outer liquid masses. Furthermore, for the most viscous drops they enter the pool trailing a viscous thread reaching all the way to the pinch-off nozzle. The air sheet can also wrap around this thread and remain stable over an extended period of time to form a cylindrical air sheet. We study the parameter regime where these structures appear and their subsequent breakup. The stability of these thin cylindrical air sheets is inconsistent with inviscid stability theory, suggesting stabilization by lubrication forces within the submicron air layer. We use interferometry to measure the air-layer thickness versus depth along the cylindrical air sheet and around the drop. The air film is thickest above the equator of the drop, but thinner below the drop and up along the air cylinder. Based on microbubble volumes, the thickness of the cylindrical air layer becomes less than 100 nm before it ruptures.

  6. Plasmoid formation in the elongated current sheet during transient CHI on HIST

    Science.gov (United States)

    Nagata, Masayoshi; Fujita, Akihiro; Matsui, Takahiro; Kikuchi, Yusuke; Fukumoto, Naoyuki; Kanki, Takashi

    2016-10-01

    The Transient-Coaxial Helicity Injection (T-CHI) is a promising candidate for the non-inductive plasma start-up on Spherical Torus (ST). The problem of the flux closure in the T-CHI is important and related to understand the physics of fast magnetic reconnection. The recent MHD simulation (F. Ebrahimi and R. Raman, Phys. Rev. Lett. 114, 205003 (2015)) on T-CHI for NSTX predicts the formation and breakup of an elongated Sweet-Parker (S-P) current sheet and a transient to plasmoid instability. According to this simulation, the reconnection rate based on the plasmoid instability is faster than that by S-P model and becomes nearly independent of the Lundquist number S. In this meeting, we will present that the formation of multiple X-points and plasmoids has been observed in T-CHI start-up plasmas on HIST. The stronger external guide (toroidal) magnetic field makes plasma less compressible, leading to slower reconnection time and longer current sheet. The experimental observation shows that 2/3 plasmoids are generated in the elongated current sheet with the narrow width comparable to the ion skin depth or the ion sound gyro-radius. The small plasmoids develop to a large-scale flux structure due to a current inward diffusion during the decay phase.

  7. Elevated blood plasma levels of epinephrine, norepinephrine, tyrosine hydroxylase, TGFβ1, and TNFα associated with high-altitude pulmonary edema in an Indian population

    Science.gov (United States)

    Pandey, Priyanka; Ali, Zahara; Mohammad, Ghulam; Pasha, M A Qadar

    2016-01-01

    Biomarkers are essential to unravel the locked pathophysiology of any disease. This study investigated the role of biomarkers and their interactions with each other and with the clinical parameters to study the physiology of high-altitude pulmonary edema (HAPE) in HAPE-patients (HAPE-p) against adapted highlanders (HLs) and healthy sojourners, HAPE-controls (HAPE-c). For this, seven circulatory biomarkers, namely, epinephrine, norepinephrine, tyrosine hydroxylase, transforming growth factor beta 1, tumor necrosis factor alpha (TNFα), platelet-derived growth factor beta beta, and C-reactive protein (CRP), were measured in blood plasma of the three study groups. All the subjects were recruited at ~3,500 m, and clinical features such as arterial oxygen saturation (SaO2), body mass index, and mean arterial pressure were measured. Increased levels of epinephrine, norepinephrine, tyrosine hydroxylase, transforming growth factor-beta 1, and TNFα were observed in HAPE-p against the healthy groups, HAPE-c, and HLs (P0.01). Correlation analysis revealed a negative correlation between epinephrine and norepinephrine (P=4.6E−06) in HAPE-p and positive correlation in HAPE-c (P=0.004) and HLs (P=9.78E−07). A positive correlation was observed between TNFα and CRP (P=0.004) in HAPE-p and a negative correlation in HAPE-c (P=4.6E−06). SaO2 correlated negatively with platelet-derived growth factor beta beta (HAPE-p; P=0.05), norepinephrine (P=0.01), and TNFα (P=0.005) and positively with CRP (HAPE-c; P=0.02) and norepinephrine (HLs; P=0.04). Body mass index correlated negatively with epinephrine (HAPE-p; P=0.001) and positively with norepinephrine and tyrosine hydroxylase in HAPE-c (P0.70, P<0.05). The results clearly suggest that increased plasma levels of these circulatory biomarkers associated with HAPE. PMID:27540296

  8. PATTERN AND SEVERITY OF DIASTOLIC DYSFUNCTION IN ORGANOPHOSPHORUS COMPOUND POISONING PATIENTS IN RELATION TO PLASMA CHOLINESTERASE (PC h E LEVEL IN RURAL POPULATION IN SOUTH INDIA

    Directory of Open Access Journals (Sweden)

    Prashant S

    2015-07-01

    Full Text Available BACKGROUND : Organophosphorus (OP poisoning is a major public health problem in developing world. OP pesticides inhibit carboxylic esterase enzymes including plasma cholinesterase (PChE. Clinical manifestations following OP poisoning can be associated with the extent of decrease of PChE. This study was designed to investigate the relevance of diastolic function of the heart, severity of diastolic dysfunction and the reversibility of dysfunction in organophosphoru s compound poisoning patients in relation to plasma cholinesterase (PChE levels with the treatment. MATERIALS AND METHODS : 76 patients admitted with organophosphorus compound poisoning were evaluated for diastolic dysfunction by echocardiography. Clinical features and the nature of compound involved were recorded. Severity of diastolic dysfunction was assessed. Cholinesterase levels were assessed. Initially there was worsening of diastolic function. As the treatment progressed, there was improvement in the pattern of diastolic dysfunction with the corresponding improvement in cholinesterase level and clinical improvement. This was a cross - sectional study which was conducted from 1st January 2014 to February 2015. RESULTS : In total, mean age of patients were 31.2 (range : 19 - 46 years. Majority of patients were females (68.4%, and agricultural workers (75%. Main clinical findings at the time of admission were congested conjunctiva (83%, pin point pupil (89%, lacrimation (78%, vomiting (69%, non - reactive pupil (85%, respiratory distress (65% and abdominal pain (45%. Mean (SD PChE at 6 hours post - exposure was 3242.6 IU/L. At presentation, cyanosis, muscle weakness, convulsion, respiratory distress and fasciculation were related to cases with >75%reducti on of PChE, while, constricted and nonreactive pupil, lacrimation and congested conjunctivae were related to cases with 50 - 75% reduction and abdominal pain, dryness of conjunctiva, vomiting and diarrhea were related to <50

  9. Streaming sausage, kink and tearing instabilities in a current sheet with applications to the earth's magnetotail

    Science.gov (United States)

    Lee, L. C.; Wang, S.; Wei, C. Q.; Tsurutani, B. T.

    1988-01-01

    This paper investigates the growth rates and eigenmode structures of the streaming sausage, kink, and tearing instabilities in a current sheet with a super-Alfvenic flow. The growth rates and eigenmode structures are first considered in the ideal incompressible limit by using a four-layer model, as well as a more realistic case in which all plasma parameters and the magnetic field vary continuously along the direction perpendicular to the magnetic field and plasma flow. An initial-value method is applied to obtain the growth rate and eigenmode profiles of the fastest growing mode, which is either the sausage mode or kink mode. It is shown that, in the earth's magnetotail, where super-Alfvenic plasma flows are observed in the plasma sheet and the ratio between the plasma and magnetic pressures far away from the current layer is about 0.1-0.3 in the lobes, the streaming sausage and streaming tearing instabilities, but not kink modes, are likely to occur.

  10. Streaming sausage, kink and tearing instabilities in a current sheet with applications to the earth's magnetotail

    Science.gov (United States)

    Lee, L. C.; Wang, S.; Wei, C. Q.; Tsurutani, B. T.

    1988-01-01

    This paper investigates the growth rates and eigenmode structures of the streaming sausage, kink, and tearing instabilities in a current sheet with a super-Alfvenic flow. The growth rates and eigenmode structures are first considered in the ideal incompressible limit by using a four-layer model, as well as a more realistic case in which all plasma parameters and the magnetic field vary continuously along the direction perpendicular to the magnetic field and plasma flow. An initial-value method is applied to obtain the growth rate and eigenmode profiles of the fastest growing mode, which is either the sausage mode or kink mode. It is shown that, in the earth's magnetotail, where super-Alfvenic plasma flows are observed in the plasma sheet and the ratio between the plasma and magnetic pressures far away from the current layer is about 0.1-0.3 in the lobes, the streaming sausage and streaming tearing instabilities, but not kink modes, are likely to occur.

  11. Immigrant Education: A Fact Sheet.

    Science.gov (United States)

    Aleman, Steven R.

    This report provides information on immigrant education in the United States in the areas of funding, participation, population, services, and allocation method. Additionally, it explores reauthorization issues confronting the Emergency Immigrant Education Act for fiscal year 1994. The report shows that: (1) there has been a steady decrease in…

  12. MTNR1B G24E variant associates With BMI and fasting plasma glucose in the general population in studies of 22,142 Europeans

    DEFF Research Database (Denmark)

    Andersson, Ehm A; Holst, Birgitte; Sparsø, Thomas

    2010-01-01

    , type 2 diabetes, or related metabolic traits. RESEARCH DESIGN AND METHODS: MTNR1B was sequenced in 47 probands with clinical maturity-onset diabetes of the young (MODY), in 51 probands with early-onset familial type 2 diabetes, and in 94 control individuals. Six nonsynonymous variants (G24E, L60R, V124......OBJECTIVE: Common variants in the melatonin receptor type 1B (MTNR1B) locus have been shown to increase fasting plasma glucose (FPG) and the risk of type 2 diabetes. The aims of this study were to evaluate whether nonsynonymous variants in MTNR1B associate with monogenic forms of hyperglycemia......I, R138C, R231H, and K243R) were genotyped in up to 22,142 Europeans. Constitutive and melatonin-induced signaling was characterized for the wild-type melatonin receptor type 1B (MT2) and the 24E, 60R, and 124I MT2 mutants in transfected COS-7 cells. RESULTS: No mutations in MTNR1B were MODY...

  13. Review of Incremental Forming of Sheet Metal Components

    Directory of Open Access Journals (Sweden)

    Nimbalkar D.H

    2013-09-01

    Full Text Available Incremental sheet forming has demonstrated its great potential to form complex three dimensional parts without using a component specific tooling. The die-less nature in incremental forming provides competitive alternative for economically and effectively fabricating low volume functional sheet products. The process locally deforms sheet metal using a moving tool head achieving higher forming limit than those conventional sheet metal stamping process. Incremental sheet metal forming has the potential to revolutionize sheet metal forming, making it accessible to all level of manufacturing. This paper describes the current state of the art of Incremental sheet metal forming.

  14. On sea level - ice sheet interactions

    Science.gov (United States)

    Gomez, Natalya Alissa

    This thesis focuses on the physics of static sea-level changes following variations in the distribution of grounded ice and the influence of these changes on the stability and dynamics of marine ice sheets. Gravitational, deformational and rotational effects associated with changes in grounded ice mass lead to markedly non-uniform spatial patterns of sea-level change. I outline a revised theory for computing post-glacial sea-level predictions and discuss the dominant physical effects that contribute to the patterns of sea-level change associated with surface loading on different timescales. I show, in particular, that a large sea-level fall (rise) occurs in the vicinity of a retreating (advancing) ice sheet on both short and long timescales. I also present an application of the sea-level theory in which I predict the sea-level changes associated with a new model of North American ice sheet evolution and consider the implications of the results for efforts to establish the sources of Meltwater Pulse 1A. These results demonstrate that viscous deformational effects can influence the amplitude of sea-level changes observed at far-field sea-level sites, even when the time window being considered is relatively short (≤ 500 years). Subsequently, I investigate the feedback of sea-level changes on marine ice-sheet stability and dynamics by coupling a global sea-level model to ice-sheet models of increasing complexity. To begin, I incorporate gravitationally self-consistent sea-level changes into an equilibrium marine ice-sheet stability theory to show that the sea-level changes have a stabilizing influence on ice-sheet retreat. Next, I consider the impact of the stabilizing mechanism on the timescale of ice-sheet retreat using a 1D dynamic coupled ice sheet - sea level model. Simulations with the coupled model, which incorporate viscoelastic deformation of the solid Earth, show that local sea-level changes at the grounding line act to slow, and in some cases, halt

  15. Advanced plasma diagnostics for plasma processing

    Science.gov (United States)

    Malyshev, Mikhail Victorovich

    1999-10-01

    A new, non-intrusive, non-perturbing diagnostic method was developed that can be broadly applied to low pressure, weakly ionized plasmas and glow discharges-trace rare gases optical emission spectroscopy (TRG-OES). The method is based on a comparison of intensities of atomic emission from trace amounts of inert gases (He, Ne, Ar, Kr, and Xe) that are added to the discharge to intensities calculated from the theoretical model. The model assumes a Maxwellian electron energy distribution function (EEDF), computes the population of emitting levels both from the ground state and the metastable states of rare gases, and from the best fit between theory and experiment determines electron temperature (Te). Subject to conditions, TRG-OES can also yield electron density or its upper or lower limit. From the comparison of the emission from levels excited predominantly by high energy electrons to that excited by low energy electrons, information about the EEDF can be obtained. The use of TRG-OES also allows a traditionally qualitative actinometry technique (determination of concentration of radical species in plasma through optical emission) to become a precise quantitative method by including Te and rare gases metastables effects. A combination of TRG-OES, advanced actinometry, and Langmuir probe measurements was applied to several different plasma reactors and regimes of operation. Te measurements and experiments to correct excitation cross section were conducted in a laboratory helical resonator. Two chamber configuration of a commercial (Lam Research) metal etcher were studied to determine the effects of plasma parameters on plasma-induced damage. Two different methods (RF inductive coupling and ultra-high frequency coupling) for generating a plasma in a prototype reactor were also studied. Pulsed plasmas, a potential candidate to eliminate the plasma-induced damage to microelectronics devices that occurs in manufacturing due to differential charging of the wafer, have

  16. Elevated blood plasma levels of epinephrine, norepinephrine, tyrosine hydroxylase, TGFβ1, and TNFα associated with high-altitude pulmonary edema in Indian population

    Directory of Open Access Journals (Sweden)

    Pandey P

    2016-08-01

    Full Text Available Priyanka Pandey,1,2 Zahara Ali,1,2 Ghulam Mohammad,3 MA Qadar Pasha1,2 1Functional Genomics Unit, CSIR-Institute of Genomics and Integrative Biology, Delhi, 2Department of Biotechnology, Savitribai Phule Pune University, Pune, 3Department of Medicine, SNM Hospital, Ladakh, Jammu and Kashmir, India Abstract: Biomarkers are essential to unravel the locked pathophysiology of any disease. This study investigated the role of biomarkers and their interactions with each other and with the clinical parameters to study the physiology of high-altitude pulmonary edema (HAPE in HAPE-patients (HAPE-p against adapted highlanders (HLs and healthy sojourners, HAPE-controls (HAPE-c. For this, seven circulatory biomarkers, namely, epinephrine, norepinephrine, tyrosine hydroxylase, transforming growth factor beta 1, tumor necrosis factor alpha (TNFα, platelet-derived growth factor beta beta, and C-reactive protein (CRP, were measured in blood plasma of the three study groups. All the subjects were recruited at ~3,500 m, and clinical features such as arterial oxygen saturation (SaO2, body mass index, and mean arterial pressure were measured. Increased levels of epinephrine, norepinephrine, tyrosine hydroxylase, transforming growth factor-beta 1, and TNFα were observed in HAPE-p against the healthy groups, HAPE-c, and HLs (P<0.0001. CRP levels were decreased in HAPE-p against HAPE-c and HLs (P<0.0001. There was no significant difference or very marginal difference in the levels of these biomarkers in HAPE-c and HLs (P>0.01. Correlation analysis revealed a negative correlation between epinephrine and norepinephrine (P=4.6E-06 in HAPE-p and positive correlation in HAPE-c (P=0.004 and HLs (P=9.78E-07. A positive correlation was observed between TNFα and CRP (P=0.004 in HAPE-p and a negative correlation in HAPE-c (P=4.6E-06. SaO2 correlated negatively with platelet-derived growth factor beta beta (HAPE-p; P=0.05, norepinephrine (P=0.01, and TNFα (P=0.005 and

  17. Plasma Tryptophan and the Kynurenine–Tryptophan Ratio Are Associated with the Acquisition of Statural Growth Deficits and Oral Vaccine Underperformance in Populations with Environmental Enteropathy

    Science.gov (United States)

    Kosek, Margaret N.; Mduma, Estomih; Kosek, Peter S.; Lee, Gwenyth O.; Svensen, Erling; Pan, William K. Y.; Olortegui, Maribel Paredes; Bream, Jay H.; Patil, Crystal; Asayag, Cesar Ramal; Sanchez, Graciela Meza; Caulfield, Laura E.; Gratz, Jean; Yori, Pablo Peñataro

    2016-01-01

    Early childhood enteric infections have adverse impacts on child growth and can inhibit normal mucosal responses to oral vaccines, two critical components of environmental enteropathy. To evaluate the role of indoleamine 2,3-dioxygenase 1 (IDO1) activity and its relationship with these outcomes, we measured tryptophan and the kynurenine–tryptophan ratio (KTR) in two longitudinal birth cohorts with a high prevalence of stunting. Children in rural Peru and Tanzania (N = 494) contributed 1,251 plasma samples at 3, 7, 15, and 24 months of age and monthly anthropometrics from 0 to 36 months of age. Tryptophan concentrations were directly associated with linear growth from 1 to 8 months after biomarker assessment. A 1-SD increase in tryptophan concentration was associated with a gain in length-for-age Z-score (LAZ) of 0.17 over the next 6 months in Peru (95% confidence interval [CI] = 0.11–0.23, P < 0.001) and a gain in LAZ of 0.13 Z-scores in Tanzania (95% CI = 0.03–0.22, P = 0.009). Vaccine responsiveness data were available for Peru only. An increase in kynurenine by 1 μM was associated with a 1.63 (95% CI = 1.13–2.34) increase in the odds of failure to poliovirus type 1, but there was no association with tetanus vaccine response. A KTR of 52 was 76% sensitive and 50% specific in predicting failure of response to serotype 1 of the oral polio vaccine. KTR was associated with systemic markers of inflammation, but also interleukin-10, supporting the association between IDO1 activity and immunotolerance. These results strongly suggest that the activity of IDO1 is implicated in the pathophysiology of environmental enteropathy, and demonstrates the utility of tryptophan and kynurenine as biomarkers for this syndrome, particularly in identifying those at risk for hyporesponsivity to oral vaccines. PMID:27503512

  18. Elemental ratios for characterization of quantum-dots populations in complex mixtures by asymmetrical flow field-flow fractionation on-line coupled to fluorescence and inductively coupled plasma mass spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    Menendez-Miranda, Mario; Fernandez-Arguelles, Maria T.; Costa-Fernandez, Jose M., E-mail: jcostafe@uniovi.es; Encinar, Jorge Ruiz; Sanz-Medel, Alfredo, E-mail: asm@uniovi.es

    2014-08-11

    Highlights: • The hyphenated system allows unequivocal identification of nanoparticle populations. • AF4 separation permitted detection of unexpected nanosized species in a sample. • ICP-QQQ provides elemental ratios with adequate accuracy in every nanoparticle. • Purity and chemical composition of different quantum dot samples were assessed. - Abstract: Separation and identification of nanoparticles of different composition, with similar particle diameter, coexisting in heterogeneous suspensions of polymer-coated CdSe/ZnS quantum dots (QDs) have been thoroughly assessed by asymmetric flow field-flow fractionation (AF4) coupled on-line to fluorescence and inductively coupled plasma mass spectrometry (ICPMS) detectors. Chemical characterization of any previously on-line separated nanosized species was achieved by the measurement of the elemental molar ratios of every element involved in the synthesis of the QDs, using inorganic standards and external calibration by flow injection analysis (FIA). Such elemental molar ratios, strongly limited so far to pure single nanoparticles suspensions, have been achieved with adequate accuracy by coupling for the first time an ICP-QQQ instrument to an AF4 system. This hyphenation turned out to be instrumental to assess the chemical composition of the different populations of nanoparticles coexisting in the relatively complex mixtures, due to its capabilities to detect the hardly detectable elements involved in the synthesis. Interestingly such information, complementary to that obtained by fluorescence, was very valuable to detect and identify unexpected nanosized species, present at significant level, produced during QDs synthesis and hardly detectable by standard approaches.

  19. Comparison of manufacturing of lightweight corrugated sheet sandwiches by hydroforming and incremental sheet forming

    Science.gov (United States)

    Maqbool, Fawad; Elze, Lars; Seidlitz, Holger; Bambach, Markus

    2016-10-01

    Sandwich materials made from corrugated sheet metal provide excellent mechanical properties for lightweight design without using filler material. The increased mechanical properties of these sandwich materials are achieved by the 3-D geometry of the corrugated sheet and the hardening due to pre-forming. In the present study, manufacturing of corrugated sheet metal consisting of hexagonal bulge patterns through hydroforming and incremental forming is analyzed. Double layered corrugated sheet metal sandwiches with hexagonal patterns of free-form bulge geometries are investigated through finite element analysis for the maximum increase in stiffness over the normal flat sheets. The analysis shows that a bending stiffness increase of up to 13 times over flat sheet of the same mass is attainable by corrugated sandwiches. Further, it is proved for these types of corrugation sandwiches that stiffness increases by increasing the height of the corrugation bulge but that hydroforming poses restrictions with respect to bulge height, since it is limited by forming force and formability of the material. Incremental sheet metal forming can be used to produce sheets with a hexagonal bulge pattern with increased height. Hence, a higher increase in stiffness as compared to hydroforming is possible but at the expense of process speed.

  20. Best Management Practice, Fact Sheet 2. Sheet Flow to Open Space

    OpenAIRE

    2013-01-01

    This publication explains what sheet flow to open space is, where and how it is used, their limitations, routine and nonroutine maintenance, expected costs, and a glossary of terms. This fact sheet is one of a 15-part series on urban stormwater management practices.