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Sample records for plant diagnostics study

  1. Nuclear power plant diagnostics study at the Midland training simulator

    International Nuclear Information System (INIS)

    Reifman, J.; Rank, P.; Lee, J.C.

    1991-01-01

    Training simulators provide a real world environment for testing advanced diagnostic and control systems as an aid to nuclear power plant operators. The simulators not only duplicate the hardware din the actual control room, allowing for analysis of man-machine interface, but also represent the dynamic behavior of the reference plant in real-time, in a realistic manner. Training simulators provide the means to representing the reference plant operations in a wide range of operation conditions including off-normal and emergency conditions. Transient events with very low probability of occurrence can then be represented and used to test the capabilities of advanced diagnostic and control systems. For these reasons, full-scope operator training simulators have been used as a test bed for a number of advanced diagnostic concepts. The University of Michigan and Consumers Power Company have been collaborating in a program devoted to the development and study of advanced concepts for automatic diagnostics and control of nuclear power plants. The program has been focused on the use of the full-scope operator training Midland Nuclear Power Plant Unit 2 (MNP-2) Simulator for development, testing, and verification of advanced diagnostics concepts. In their current efforts, the authors have developed two artificial intelligent (AI) diagnostic concepts that have been applied to the MNP-2 Simulator: the systematic generation and updating of a rule-based knowledge system for nuclear power plant diagnostics and a nonlinear parameter estimation algorithm called the simulation filter. The simulation filter algorithm is used with the MNP-2 Simulator to improve the simulation of the Three Mile Island Unit 2 (TMI-2) accident. 11 refs., 4 figs

  2. Advance in study of intelligent diagnostic method for nuclear power plant

    International Nuclear Information System (INIS)

    Zhou Gang; Yang Li

    2008-01-01

    The advance of research on the application of three types of intelligent diagnostic approach based on neural network (ANN), fuzzy logic and expert system to the operation status monitoring and fault diagnosis of nuclear power plant (NPP) was reviewed. The research status and characters on status monitoring and fault diagnosis approaches based on neural network, fuzzy logic and expert system for nuclear power plant were analyzed. The development trend of applied research on intelligent diagnostic approaches for nuclear power plant was explored. The analysis results show that the research achievements on intelligent diagnostic approaches based on fuzzy logic and expert system for nuclear power plant are not much relatively. The research of intelligent diagnostic approaches for nuclear power plant concentrate on the aspect of operation status monitoring and fault diagnosis based on neural networks for nuclear power plant. The advancing tendency of intelligent diagnostic approaches for nuclear power plant is the combination of various intelligent diagnostic approaches, the combination of neural network diagnostic approaches and other diagnostic approaches as well as multiple neural network diagnostic approaches. (authors)

  3. Plant diagnostics in power stations

    International Nuclear Information System (INIS)

    Sturm, A.; Doering, D.

    1985-01-01

    The method of noise diagnostics is dealt with as a part of plant diagnostics in nuclear power stations. The following special applications are presented: (1) The modular noise diagnostics system is used for monitoring primary coolant circuits and detecting abnormal processes due to mechanical vibrations, loose parts or leaks. (2) The diagnostics of machines and plants with antifriction bearings is based on bearing vibration measurements. (3) The measurement of the friction moment by means of acoustic emission analysis is used for evaluating the operational state of slide bearings

  4. Nuclear power plant diagnostics study at the Midland Training Simulator

    International Nuclear Information System (INIS)

    Reifman, J.; Rank, P.; Lee, J.C.; Wehe, D.K.

    1991-01-01

    This paper discusses the implementation of two advanced diagnostic concepts for nuclear power plant diagnostics, the systematic generation and updating of a rule-based system and the simulation filter, at the Midland Nuclear Power Plant Unit 2 Training Simulator. The authors use an entropy minimax pattern recognition algorithm for the systematic construction of the diagnostic rule base. By extracting information from a transient database constructed with the Midland Simulator, the algorithm searches for trends in plant parameters, forming patterns or rules that describe the behavior of the transients. The rules are updated in an incremental manner within the context of the entropy minimax algorithm. The simulation filter is a nonlinear parameter estimation algorithm based on the extended Kalman filter. The authors use the simulation filter to improve the results of crude simulation models by optimally estimating system states given a set of measurements and results from a nonlinear simulation program. The Midland Simulator results of the Three Mile Island accident are significantly improved with the use of the simulation filter

  5. Nuclear power plant diagnostic system

    International Nuclear Information System (INIS)

    Prokop, K.; Volavy, J.

    1982-01-01

    Basic information is presented on diagnostic systems used at nuclear power plants with PWR reactors. They include systems used at the Novovoronezh nuclear power plant in the USSR, at the Nord power plant in the GDR, the system developed at the Hungarian VEIKI institute, the system used at the V-1 nuclear power plant at Jaslovske Bohunice in Czechoslovakia and systems of the Rockwell International company used in US nuclear power plants. These diagnostic systems are basically founded on monitoring vibrations and noise, loose parts, pressure pulsations, neutron noise, coolant leaks and acoustic emissions. The Rockwell International system represents a complex unit whose advantage is the on-line evaluation of signals which gives certain instructions for the given situation directly to the operator. The other described systems process signals using similar methods. Digitized signals only serve off-line computer analyses. (Z.M.)

  6. Integration of the ITER diagnostic plant systems with CODAC

    International Nuclear Information System (INIS)

    Simrock, S.; Barnsley, R.; Bertalot, L.; Hansalia, C.; Klotz, W.D.; Makijarvi, P.; Reichle, R.; Vayakis, G.; Yonekawa, I.; Walker, C.; Wallander, A.; Walsh, M.; Winter, A.

    2011-01-01

    ITER requires extensive diagnostic systems in order to meet the requirements for machine operation, protection, plasma control and physics studies. The realization of these systems is a major challenge not only because of the harsh environment and the nuclear requirements but also with respect to Instrumentation and Control (I and C) of all the 59 diagnostics plants. The Plant Systems I and C are mostly 'in-kind', i.e. procured by the seven ITER Domestic Agencies (DAs), while the Central I and C Systems are 'in-fund', i.e. procured by ITER Organization (IO). Standardization of Plant Systems I and C is of primary importance and has been one of the highest priority tasks of CODAC. The standards are published in the Plant Control Design Handbook (PCDH) which will be followed to ensure a homogeneous design, guarantee high availability and simplify maintenance and support future upgrades. Most important for a successful commissioning and operation of the ITER facility are the concepts of interfacing the diagnostics plant systems with CODAC and the standards for instrumentation and control which must be followed all contributing parties. In this paper, we will elaborate on the concepts of interfacing the diagnostics plant systems with CODAC and the standards that must be followed for the design.

  7. Knowledge acquisition for nuclear power plant unit diagnostic system

    International Nuclear Information System (INIS)

    Li Xiaodong; Xi Shuren

    2003-01-01

    The process of acquiring knowledge and building a knowledge base is critical to realize fault diagnostic system at unit level in a nuclear power plant. It directly determines whether the diagnostic system can be applied eventually in a commercial plant. A means to acquire knowledge and its procedures was presented in this paper for fault diagnostic system in a nuclear power plant. The work can be carried out step by step and it is feasible in a commercial nuclear power plant. The knowledge base of the fault diagnostic system for a nuclear power plant can be built after the staff finish the tasks according to the framework presented in this paper

  8. Diagnostic technology of PWR plant equipment failures

    International Nuclear Information System (INIS)

    Nakamura, Tetsuo; Tanaka, Mamoru; Okamachi, Masao; Taguchi, Shozo; Nagashima, Kazuhiro; Ishikawa, Satoshi

    1985-01-01

    To confirm the soundness of the important facilities in a nuclear power plant contributes to the reliability of the plant operations and improvement of its operation rate. For this purpose, the following diagnostic techniques have been developed. (1). Vibration and loose parts monitoring: Detection of abnormal structural vibrations in the reactor, estimation of its mode, detection of loose parts in the primary system, and estimation of the position and energy of their collisions against the reactor vessel or the like. (2). Valve leak monitoring: Detection of leaks from primary valves in the primary cooling boundary, such as the pressurizer relief valve and safety valve, and estimation of the form of the leaks. (3). Detector noise response diagnosis: Diagnosis of degradation of principal process detectors during plant operation. Furthermore, a diagnostic system incorporating the above diagnostic technology applicable to actual plants has been experimentally manufactured and successfully verified. (author)

  9. Study for the design method of multi-agent diagnostic system to improve diagnostic performance for similar abnormality

    International Nuclear Information System (INIS)

    Minowa, Hirotsugu; Gofuku, Akio

    2014-01-01

    Accidents on industrial plants cause large loss on human, economic, social credibility. In recent, studies of diagnostic methods using techniques of machine learning such as support vector machine is expected to detect the occurrence of abnormality in a plant early and correctly. There were reported that these diagnostic machines has high accuracy to diagnose the operating state of industrial plant under mono abnormality occurrence. But the each diagnostic machine on the multi-agent diagnostic system may misdiagnose similar abnormalities as a same abnormality if abnormalities to diagnose increases. That causes that a single diagnostic machine may show higher diagnostic performance than one of multi-agent diagnostic system because decision-making considering with misdiagnosis is difficult. Therefore, we study the design method for multi-agent diagnostic system to diagnose similar abnormality correctly. This method aimed to realize automatic generation of diagnostic system where the generation process and location of diagnostic machines are optimized to diagnose correctly the similar abnormalities which are evaluated from the similarity of process signals by statistical method. This paper explains our design method and reports the result evaluated our method applied to the process data of the fast-breeder reactor Monju

  10. Study of methodology diversification in diagnostics

    International Nuclear Information System (INIS)

    Suda, Kazunori; Yonekawa, Tsuyoshi; Yoshikawa, Shinji; Hasegawa, Makoto

    1999-03-01

    There are several research activities to enhance safety and reliability of nuclear power plant operation and maintenance. We are developing a concept of an autonomous operation system where the role of operators is replaced with artificial intelligence. The purpose of the study described in this report is to develop a operator support system in abnormal plant situations. Conventionally, diagnostic modules based on individual methodology such as expert system have been developed and verified. In this report, methodology diversification is considered to integrate diagnostic modules which performance are confirmed using information processing technique. Technical issues to be considered in diagnostic methodology diversification are; 1)reliability of input data, 2)diversification of knowledge models, algorithms and reasoning schemes, 3)mutual complement and robustness. The diagnostic module utilizing the different approaches defined along with strategy of diversification was evaluated using fast breeder plant simulator. As a result, we confirmed that any singular diagnostic module can not meet accuracy criteria for the entire set of anomaly events. In contrast with this, we confirmed that every abnormality could be precisely diagnosed by a mutual combination. In other words, legitimacy of approach selected by strategy of diversification was shown, and methodology diversification attained clear efficiency for abnormal diagnosis. It has been also confirmed that the diversified diagnostic system implemented in this study is able to maintain its accuracy even in case that encountered scale of abnormality is different from reference cases embedded in the knowledge base. (author)

  11. Development and implementation of plant diagnostic skills training

    International Nuclear Information System (INIS)

    Iwatare, K.; Noji, K.

    2010-01-01

    It was learned from the July 2007 Chuetsu-oki Earthquake that a need exists for simulator training methods to be revised to include the assumption of multiple failures such as those which may occur during a large earthquake. At BWR Operator Training Center Corp., multiple failure team training which focuses on plant diagnostic skills (Plant Diagnostic Skills Training) has been developed and implemented since September 2008. The contents of this training along with the results are presented and considered in this paper. (author)

  12. Training diagnostic skills for nuclear power plants

    International Nuclear Information System (INIS)

    Goodstein, L.P.

    1986-11-01

    Operators of large-scale industrial process plants such as nuclear power stations and chemical plants are faced with a critical and complex task when confronted with disturbances in normal operation caused by technical failures or mainte- nances errors. Great care must be taken to prepare and support the operators during such situations. Procedural systems are provided, trained on full-scale highfidelity simulators is often a prerequisite and decision-support systems are starting to be incorporated, especially in modern control rooms. During recent years, it has become increasingly clear from ''real-life'' studies in complex production and transport industries that professional highly skilled troubleshooters can develop effective general purpose search strategies for locating and dealing with faults and, most importantly, with new and not previously experienced faults. This research has indicated that means for training of these general diagnostic abilities can be developed. In addition, other work has dealt with the problem of observing and analyzing operator behaviour in coping with disturbances. The NKA/LIT-4 project has continued these efforts in studying methods for training diagnostic skills as well as for observing and testing operator behaviour on training simulators. (author)

  13. Experience with diagnostic instrumentation in nuclear power plants

    International Nuclear Information System (INIS)

    Gopal, R.; Ciaramitaro, W.

    1977-01-01

    Over the past several years, Westinghouse has developed a coordinated system of on-line diagnostic instrumentation for the acquisition and analysis of data for diagnostics and incipient failure detection of critical plant equipment and systems. Primary motivation for this work is to improve NSSS availability and Maintainability through the detection of malfunctions at their inception. These systems encompass the following areas: (1) Vibration Monitoring System for detection of changes in vibrational characteristics of the major components of Nuclear Steam Supply System (NSSS) and Balance of Plant (BOP); (2) Acoustic Monitoring System for detection and location of leaks in the primary system pressure boundary and other piping systems in PWRs; (3) Metal Impact Monitoring for detection of loose debris in the reactor vessel and steam generators; (4) Nuclear Noise Monitoring System for monitoring core barrel vibration; (5) Sensor Response Time Measurement System for detecting any degradation of process sensors; and (6) Transit Time Flow Meter for determining primary coolant flow rate. Summarized in this paper are some of the features of the systems and in-plant experience. These experiences demonstrate that diagnostic systems in combination with analytical and laboratory work for data interpretation do improve plant availability. (author)

  14. Study on diagnostic plant analyzer method for support of emergency operation

    International Nuclear Information System (INIS)

    Yoshikawa, H.; Gofuku, A.; Itoh, K.; Wakabayashi, J.

    1986-01-01

    Methods of time-critical diagnostic plant analyzer are investigated which would serve as support to emergency operation of nuclear power plant. A faster-than-real-time simulator code TOKRAC is developed for analyzing PWR primary loop thermo-hydraulics of small-break LOCA and it is applied for a numerical experiment of initial phase of TMI-2 accident. TOKRAC resulted in a good agreement with a RELAP4/MOD6 calculation and the plant record with as fast as can one-tenth of real time. A real-time estimator of SG heat transfer rate based on Kalman filter is proposed and its applicability is verified using LOFT ATWS experimental data. With regards to how to integrate those methods into the software system in operation support center, a new concept of module-based simulation system is proposed which aims at offering a flexible and human-cognitive oriented environment for various analytical tool development

  15. Development trends for diagnostic systems in nuclear power plants

    International Nuclear Information System (INIS)

    Kunze, U.; Pohl, U.

    1998-01-01

    Monitoring systems used in nuclear power plants have made remarkable progress over the past four or five years. Development has followed the trends and changes in philosophy for the purpose of monitoring systems in nuclear power plants: They are no longer expected to fulfill only safety tasks, the plant personnel require information on which to base condition-oriented maintenance. A new generation of monitoring and diagnostic systems has been developed by Siemens recently. This new generation, called Series '95, is PC-based. An overview is given for the KUeS '95 loose parts diagnostic system, the SUeS '95 vibration monitoring system, the FLUeS leak detection system and the SIPLUG valve diagnostics system. The objectives behind the development of these new systems are both safety-related and economic. The new systems improve the reliability and quality of monitoring techniques and incorporate better detection and diagnostic capabilities. Progress has also been made in automation of the systems so as to reduce routine work, give higher sensitivity for the monitoring task and reduce the scope of maintenance. (author)

  16. Diagnostic system and diagnostic experiences at the Paks Nuclear Power Plant

    International Nuclear Information System (INIS)

    Katona, Tamas

    1986-01-01

    The major functions of the diagnostic system of the first two units of the Paks Nuclear Power Plant are as follows: monitoring the mechanical integrity of the reactor and the primary coolant circuit by means of vibration diagnostics; leakage detection of the primary coolant circuit by means of high frequency sonic analysis; loose parts monitoring based on the analysis of high frequency signals of acceleration detectors; and monitoring the vibration state of the turbines and rotary machines by the latter method or by a procedure based on the detection of mechanical vibrations. Up-to-date vibration diagnostics is based on the information supplied by either acceleration detectors or pressure fluctuation detectors, or in-core and ex-core neutron detectors. (V.N.)

  17. Technical diagnostics - equipment monitoring for increasing safety and availability of nuclear power plants

    International Nuclear Information System (INIS)

    Sturm, A.; Foerster, R.

    1977-01-01

    Utilization of technical diagnostics in equipment monitoring of nuclear power plants for ensuring nuclear safety, economic availability, and for decision making on necessary maintenance is reviewed. Technical diagnostics is subdivided into inspection and early detection of malfunctions. Moreover, combination of technical diagnostics and equipment monitoring, integration of technical diagnostics into maintenance strategy, and problems of introducing early detection of malfunctions into maintenance management of nuclear power plants are also discussed. In addition, a compilation of measuring techniques used in technical diagnostics has been made. The international state of the art of equipment monitoring in PWR nuclear power plants is illustrated by description of the sound and vibration measuring techniques. (author)

  18. Study of time-critical diagnostic method for emergency operation of nuclear power plant

    International Nuclear Information System (INIS)

    Gofuku, A.; Yoshikawa, H.; Itoh, K.; Wakabayashi, J.

    1986-01-01

    In order to support the emergency operation of nuclear power plant, the method of time-critical diagnostic plant analyzer has been investigated. The conception of the emergency operation support center is proposed and two types of plant analyzer may be installed in this center. One analyzer is a real-time tracking simulation code using the observed signals and another is a fast trend-prediction code. A real-time tracking code, TOKRAC, has been developed for analyzing the PWR primary loop thermo-hydraulics at SBLOCA, and the applicability of this code was examined by the numerical experiments for the initial phase transient of both TMI-2 accident and 6% coldleg SBLOCA of a Westinghouse-type PWR plant. The results showed that fairly good tracking was carried out by TOKRAC. The CPU time of TOKRAC was about 12-14 percent of real-time

  19. Diagnostic system for combine cycle power plant

    International Nuclear Information System (INIS)

    Shimizu, Yujiro; Nomura, Masumi; Tanaka, Satoshi; Ito, Ryoji; Kita, Yoshiyuki

    2000-01-01

    We developed the Diagnostic System for Combined Cycle Power Plant which enables inexperienced operators as well as experienced operators to cope with abnormal conditions of Combined Cycle Power Plant. The features of this system are the Estimate of Emergency Level for Operation and the Prediction of Subsequent Abnormality, adding to the Diagnosis of Cause and the Operation Guidance. Moreover in this system, Diagnosis of Cause was improved by using our original method and support screens can be displayed for educational means in normal condition as well. (Authors)

  20. Applications of pattern recognition theory in diagnostics of nuclear power plants

    International Nuclear Information System (INIS)

    Cech, J.

    1982-01-01

    The questions are discussed of the application of the theory of pattern recognition in the diagnostics of nuclear power plants. For the future use of recognition systems in the diagnostics of nuclear power plants it is obvious that like with other complex systems, optimal models will have to be used which will organize the optimal recognition algorithm. The conclusion is presented that for the needs of nuclear power plants special systems will be more suitable for pattern recognition than digital computers which are flexible and adaptible but have a lower decision rate, an insufficient working memory, complicated programs, etc. (Z.M.)

  1. Utility of low-order linear nuclear-power-plant models in plant diagnostics and control

    International Nuclear Information System (INIS)

    Tylee, J.L.

    1981-01-01

    A low-order, linear model of a pressurized water reactor (PWR) plant is described and evaluated. The model consists of 23 linear, first-order difference equations and simulates all subsystems of both the primary and secondary sides of the plant. Comparisons between the calculated model response and available test data show the model to be an adequate representation of the actual plant dynamics. Suggested use for the model in an on-line digital plant diagnostics and control system are presented

  2. Advanced diagnostics and predictive maintenance to improve availability and reliability of ENEL plants

    Energy Technology Data Exchange (ETDEWEB)

    Cenci, V.; Ghironi, M.; Guidi, L.; Lauro, M.; Pestonesi, D. [ENEL (Italy). Generation and Energy Management Division

    2007-07-01

    This paper reviews the ENEL Generation and Energy Management strategy for diagnostics and predictive maintenance of power plants and provides a comprehensive description of effective applications and systems. Exploiting the most advanced information and communication technologies makes it possible to capture weak and hidden signals and powerful processing can be used to discover forewarning symptoms and identify anomalies both in the process and, above all, inside the devices. The following systems and applications are presented together with results and impact on plant profitability: expert system for the diagnostics of plant main machinery; advanced diagnostics of 'intelligent' fieldbus devices such as on/off valve motor-driven actuators, control-valve positioners and pneumatic actuators, transmitters; control loop and control valve diagnostics in order to investigate valve friction with an estimation of the residual time to failure; multisensorial diagnostics for coal transport and storage systems aimed at preventing firing and structural damages; and wireless sensor networks for the diagnostics of medium and small size components. 4 refs., 14 figs., 1 tab.

  3. Advanced DNA-Based Point-of-Care Diagnostic Methods for Plant Diseases Detection

    Directory of Open Access Journals (Sweden)

    Han Yih Lau

    2017-12-01

    Full Text Available Diagnostic technologies for the detection of plant pathogens with point-of-care capability and high multiplexing ability are an essential tool in the fight to reduce the large agricultural production losses caused by plant diseases. The main desirable characteristics for such diagnostic assays are high specificity, sensitivity, reproducibility, quickness, cost efficiency and high-throughput multiplex detection capability. This article describes and discusses various DNA-based point-of care diagnostic methods for applications in plant disease detection. Polymerase chain reaction (PCR is the most common DNA amplification technology used for detecting various plant and animal pathogens. However, subsequent to PCR based assays, several types of nucleic acid amplification technologies have been developed to achieve higher sensitivity, rapid detection as well as suitable for field applications such as loop-mediated isothermal amplification, helicase-dependent amplification, rolling circle amplification, recombinase polymerase amplification, and molecular inversion probe. The principle behind these technologies has been thoroughly discussed in several review papers; herein we emphasize the application of these technologies to detect plant pathogens by outlining the advantages and disadvantages of each technology in detail.

  4. Advanced DNA-Based Point-of-Care Diagnostic Methods for Plant Diseases Detection

    OpenAIRE

    Lau, Han Yih; Botella, Jose R.

    2017-01-01

    Diagnostic technologies for the detection of plant pathogens with point-of-care capability and high multiplexing ability are an essential tool in the fight to reduce the large agricultural production losses caused by plant diseases. The main desirable characteristics for such diagnostic assays are high specificity, sensitivity, reproducibility, quickness, cost efficiency and high-throughput multiplex detection capability. This article describes and discusses various DNA-based point-of care di...

  5. Diagnostics of subtropical plants functional state by cluster analysis

    Directory of Open Access Journals (Sweden)

    Oksana Belous

    2016-05-01

    Full Text Available The article presents an application example of statistical methods for data analysis on diagnosis of the adaptive capacity of subtropical plants varieties. We depicted selection indicators and basic physiological parameters that were defined as diagnostic. We used evaluation on a set of parameters of water regime, there are: determination of water deficit of the leaves, determining the fractional composition of water and detection parameters of the concentration of cell sap (CCS (for tea culture flushes. These settings are characterized by high liability and high responsiveness to the effects of many abiotic factors that determined the particular care in the selection of plant material for analysis and consideration of the impact on sustainability. On the basis of the experimental data calculated the coefficients of pair correlation between climatic factors and used physiological indicators. The result was a selection of physiological and biochemical indicators proposed to assess the adaptability and included in the basis of methodical recommendations on diagnostics of the functional state of the studied cultures. Analysis of complex studies involving a large number of indicators is quite difficult, especially does not allow to quickly identify the similarity of new varieties for their adaptive responses to adverse factors, and, therefore, to set general requirements to conditions of cultivation. Use of cluster analysis suggests that in the analysis of only quantitative data; define a set of variables used to assess varieties (and the more sampling, the more accurate the clustering will happen, be sure to ascertain the measure of similarity (or difference between objects. It is shown that the identification of diagnostic features, which are subjected to statistical processing, impact the accuracy of the varieties classification. Selection in result of the mono-clusters analysis (variety tea Kolhida; hazelnut Lombardsky red; variety kiwi Monty

  6. Nuclear power plant status diagnostics using artificial neural networks

    International Nuclear Information System (INIS)

    Bartlett, E.B.; Uhrig, R.E.

    1991-01-01

    In this work, the nuclear power plant operating status recognition issue is investigated using artificial neural networks (ANNs). The objective is to train an ANN to classify nuclear power plant accident conditions and to assess the potential of future work in the area of plant diagnostics with ANNS. To this end, an ANN was trained to recognize normal operating conditions as well as potentially unsafe conditions based on nuclear power plant training simulator generated accident scenarios. These scenarios include; hot and cold leg loss of coolant, control rod ejection, loss of offsite power, main steam line break, main feedwater line break and steam generator tube leak accidents. Findings show that ANNs can be used to diagnose and classify nuclear power plant conditions with good results

  7. The application of automated deductive reasoning to power plant diagnostics

    International Nuclear Information System (INIS)

    Filshtein, E.L.; Rzasa, P.W.

    1986-01-01

    A module which incorporates the application of deductive reasoning to diagnostics has been developed. This module is a part of a generic diagnostic expert system prototype developed for power plant operations at Combustion Engineering. This paper is one of a series of papers which will describe the activities of the project. Specifically, this paper describes the deductive reasoning module which determines and classifies root cause malfunctions. The concept of 'perfect instruments' is introduced. These instruments are imaginary instruments which bridge the gap between real world inputs and the generic diagnostic shell. The prototype, its application, and future developments are discussed

  8. Integration of artificial intelligence systems for nuclear power plants surveillance and diagnostics

    International Nuclear Information System (INIS)

    Chetry, Moon K.

    2012-01-01

    The objective of this program is to design, construct operate, test, and evaluate a prototype integrated monitoring and diagnostic system for a nuclear power plant. It is anticipated that this technology will have wide application to other complex systems (e.g., fossil power plants, chemical processing plants, and possibly air traffic control systems). Over the past decade, the University of Tennessee (UT) and others have carried out many projects utilizing various methodologies of artificial intelligence (expert systems, neural networks, fuzzy systems and genetic algorithms) to enhance the performance (safety, efficiency, reliability, and availability) of nuclear power plants. Investigations and studies have included a) instrumentation surveillance and calibration validation, b) inferential sensing to calibration of feed water venture flow during fouling, c) thermodynamic performance modeling with iterative improvement of plant heat rate, d) diagnosis of nuclear power plant transients

  9. Diagnostic systems in nuclear power plants. Proceedings of a technical committee meeting. Working material

    International Nuclear Information System (INIS)

    1998-01-01

    Nuclear power industry has a quite long tradition in on-line diagnostic of mechanical components and a considerable effort was put in developing diagnostic systems which are able to detect arising mechanical problems at an early stage. Computers are increasingly exploited to provide higher level information on process behaviour such as: early indication of the process deviation from normal conditions; rapid identification of the cause of any disturbance; prediction of the evolution of a disturbance; operator aid through computerized help. Following the recommendation of Several Member States to strengthen the activity in this field two divisions of IAEA established in 1995 the International Task Force on Nuclear Power Plant Diagnostics. The scope of the task force cover both technological developments and safety/licensing aspects of diagnostics. This report contains papers presented at the last in the series of Technical Committee Meetings on the Diagnostic Systems in Nuclear Power Plants organized in the framework of International Task Force

  10. Diagnostic systems in nuclear power plants. Proceedings of a technical committee meeting. Working material

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-12-31

    Nuclear power industry has a quite long tradition in on-line diagnostic of mechanical components and a considerable effort was put in developing diagnostic systems which are able to detect arising mechanical problems at an early stage. Computers are increasingly exploited to provide higher level information on process behaviour such as: early indication of the process deviation from normal conditions; rapid identification of the cause of any disturbance; prediction of the evolution of a disturbance; operator aid through computerized help. Following the recommendation of Several Member States to strengthen the activity in this field two divisions of IAEA established in 1995 the International Task Force on Nuclear Power Plant Diagnostics. The scope of the task force cover both technological developments and safety/licensing aspects of diagnostics. This report contains papers presented at the last in the series of Technical Committee Meetings on the Diagnostic Systems in Nuclear Power Plants organized in the framework of International Task Force Refs, figs, tabs

  11. The bio-positive effects of diagnostic doses of X-rays on growth of phaseolus-vulgaris plant

    Energy Technology Data Exchange (ETDEWEB)

    Mortazavi, S.M.J.; Mehdipour, L.A.; Behnejad, B.B. [Rafsanjan Univ. of Medical Sciences (Iran, Islamic Republic of)

    2006-07-01

    Objective: Plants absorb radioactive elements from phosphate fertilizers, and also from naturally occurring radiation in the soil, air and water. It has long been known that low doses of ionizing radiation evoke stimulatory effects in a wide variety of living organisms. However, as far as we know, there is no published report on the bio-positive effects of diagnostic doses of X-rays on plant growth. The aim of this study was to evaluate the bio-effects of low doses of diagnostic X-rays on growth rate of Phaseolus vulgaris (Pinto) plants. Materials and Methods: Before cultivation, Phaseolus vulgaris (Pinto) seeds were soaked in tap water for 2 days followed by another 2 days of covering under a wet cloth. Four hundred newly cultivated seeds were randomly divided into two groups of 200 plants each. In this experiment, two seeds were cultivated in each dish (100 dishes for irradiation group and 100 for sham-irradiation group). Fifteen days after starting cultivation, newly grown plants were irradiated with X-rays. Plants were exposed to a single dose of X-ray (80 kVp, 80 mAs) for 6 days. On day 29, plants were pulled out from the ' soil. Length of plant stem, length of root, number of leaves and plant weight were measured. Results: The stem length in irradiated and sham-irradiated plants was 296.5{+-}13.57 and 223.96{+-}15.02 mm respectively. This difference was statistically significant (P<0.001). Although the number of leaves in irradiated plants was higher than that of sham-irradiated plants (7.05{+-}0.18 and 6.74{+-}0.19 respectively), the difference was not statistically significant. The stem diameter in irradiated and sham-irradiated plants were 3.52{+-}0.12 and 3.35{+-}0.09 mm respectively, but the difference again was not statistically significant (P<0.00 1). Plant weight in irradiated samples was less than that of non-irradiated plants but it was not statistically significant. Conclusions: The overall results indicate that diagnostic doses of X-rays can

  12. Abnormality diagnostic technology for nuclear power plants

    International Nuclear Information System (INIS)

    Ishikawa, Satoshi

    1986-01-01

    In nuclear power plants, it is feared that the failure of the installations containing radioactive substances may inflict serious damage on public and workers. Therefore in nuclear power plants, the ensuring of safety is planned by supposing hypothetical accidents which are not likely to occur from engineering viewpoint, and multiple protection measures are taken in the plant constitution. In addition to the safety measures from such hardware aspect, recently in order to prevent the occurrence of accidents by using various safety-confirming means, and to detect early when any accident occurred, the development and putting in practical use of many monitoring equipments have been promoted. In such background, the development of nuclear power generation supporting system was carried out for five years since fiscal year 1980, subsidized by the Ministry of International Trade and Industry, and in this report, the technology of equipment abnormality diagnosis developed as a part of that project and the diagnostic techniques for actual plants are described. The technology of diagnosing nuclear reactor abnormality includes the diagnosis of loose metal pieces and the abnormal vibration of in-core structures. The detection and diagnosis of valve leak and the diagnosis of the deterioration of detectors are also explained. (Kako, I.)

  13. Application of diagnostic system for diesel engines in nuclear power plant

    International Nuclear Information System (INIS)

    Yoshinaga, Takeshi

    2004-01-01

    The diagnostic system for diesel engines makes a diagnosis of secular change and abnormal indications of diesel engines (DG) by combination of characteristic analysis of engine, lubricating oil, fuel oil, and cooling water. The principles of diagnostic system for DG, results of confirmation of the efficiency and the maintenance plan for DG in the Japan Atomic Power Company are described. DG in the company is classified to a safety device in order to supply the power source to the Emergency Core Cooling System etc., when the power source in the plant is lost, for example, at lightning struck. Characteristics of DG, outline of the diagnostic system for DG, diagnostic technologies such as engine signature analysis, chemical analysis of samples, temperature measurement, degradation mode of DG, and training in the company are stated. (S.Y.)

  14. Requirements and concepts for a nuclear plant surveillance and diagnostic system (NPSDS)

    International Nuclear Information System (INIS)

    Nicholson, P.J.; Lanning, D.D.

    1980-01-01

    An advanced plant surveillance and diagnostic system has been postulated for the purpose of aiding operator response to unanticipated plant upsets. The plant operator is described as an information processor that needs plant status information represented by symbolic outputs. These will be compatible with modern visual processing techniques, such as CRTs. Preferrred methods of estimating the state-of-the-plant and verifying measurements require on-line real-time models which are simple dynamical relationships based on energy and mass conservation laws. Implementation of on-line state estimation techniques using such models probably requires a distributed microcomputer system whose features are described. (auth)

  15. Integration of artificial intelligence systems for nuclear power plant surveillance and diagnostics

    International Nuclear Information System (INIS)

    Uhrig, R.E.; Hines, J.W.; Nelson, W.R.

    1998-01-01

    The objective of this program is to design, construct, operate, test, and evaluate a prototype integrated monitoring and diagnostic system for a nuclear power plant. It is anticipated that this technology will have wide application to other complex systems (e.g., fossil power plants, chemical processing plants, and possibly air traffic control systems). Over the past decade, the University of Tennessee (UT) and others have carried out many projects utilizing various methodologies of artificial intelligence (expert systems, neural networks, fuzzy systems, and genetic algorithms) to enhance the performance (safety, efficiency, reliability, and availability) of nuclear power plants. Investigations and studies have included a) instrumentation surveillance and calibration validation, b) inferential sensing to calibration of feedwater venturi flow during fouling, c) thermodynamic performance modeling with iterative improvement of plant beat rate, d) diagnosis of nuclear power plant transients, and e) increase in thermal power through monitoring of DNBR (Departure from Nucleate Boiling Regime). To increase the likelihood of these individual systems being used in a nuclear power plant, they must be integrated into a single system that operates virtually autonomously, collecting, interpreting, and providing information to the operators in a simple and understandable format. (author)

  16. Integration of artificial intelligence systems for nuclear power plant surveillance and diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Uhrig, R.E.; Hines, J.W.; Nelson, W.R.

    1998-07-01

    The objective of this program is to design, construct, operate, test, and evaluate a prototype integrated monitoring and diagnostic system for a nuclear power plant. It is anticipated that this technology will have wide application to other complex systems (e.g., fossil power plants, chemical processing plants, and possibly air traffic control systems). Over the past decade, the University of Tennessee (UT) and others have carried out many projects utilizing various methodologies of artificial intelligence (expert systems, neural networks, fuzzy systems, and genetic algorithms) to enhance the performance (safety, efficiency, reliability, and availability) of nuclear power plants. Investigations and studies have included a) instrumentation surveillance and calibration validation, b) inferential sensing to calibration of feedwater venturi flow during fouling, c) thermodynamic performance modeling with iterative improvement of plant beat rate, d) diagnosis of nuclear power plant transients, and e) increase in thermal power through monitoring of DNBR (Departure from Nucleate Boiling Regime). To increase the likelihood of these individual systems being used in a nuclear power plant, they must be integrated into a single system that operates virtually autonomously, collecting, interpreting, and providing information to the operators in a simple and understandable format. (author)

  17. Diagnostic knowledge generation of nuclear power plants using knowledge compilers

    International Nuclear Information System (INIS)

    Yoshikawa, Shinji; Endou, Akira; Ikeda, Mitsuru; Mizoguchi, Riichiro

    1994-01-01

    This paper discusses a method to generate diagnostic knowledge of nuclear power plants, from commonly accepted physical knowledge and design information about plant configuration. This method is based on qualitative reasoning, which is advantageous to numerical information processing in the sense that system can explain why and how directly applicable knowledge is correctly generated, and that knowledge base is highly reusable and expandable because it is independent on detailed numerical design specifications. However, reasoning ambiguity has been found as the largest problem in applying the technique to nuclear power plants. The proposed approach mainly consists of a knowledge representation scheme, reasoning algorithm, and qualitative model construction method. (author). 4 refs, 8 figs, 1 tab

  18. Trouble diagnostic system for pumps used in thermal and nuclear power plant

    International Nuclear Information System (INIS)

    Amano, K.; Hayashi, M.; Takagi, M.; Katsura, H.

    1995-01-01

    Most power plants have been operated under severe conditions to meet the diversification in electricity supply and demand. Therefore, it has become an important objective to keep the pumps under maintenance and control which necessitates a more reliable diagnostic system. With this in mind, the authors set out to perform the simulation tests of abnormal operation using a model pump, and have developed the diagnostic system for pumps based on vibration and process data. The main features of the system are 1) parallel processing of data acquisition and the diagnosis and 2) guidance function for the abnormal operation. The system has been applied to an actual pump to detect a bearing damage and set up at the nuclear power plant. (author)

  19. On-line surveillance system for Borssele nuclear power plant monitoring and diagnostics

    International Nuclear Information System (INIS)

    Tuerkcan, E.; Ciftcioglu, Oe.

    1993-08-01

    An operating on-line surveillance and diagnostic system is described where information processing for monitoring and fault diagnosis and plant maintenance are addressed. The surveillance system by means of its realtime multiprocessing, multitasking execution capabilities can perform plant-wide and wide-range monitoring for enhanced plant safety and operational reliability as well as enhanced maintenance. At the same time the system provides the possibilities for goal-oriented research and development such as estimation, filtering, verification and validation and neural networks. (orig./HP)

  20. Studies on WWER core diagnostics

    International Nuclear Information System (INIS)

    Lunin, G.L.; Mitin, V.I.; Bulavin, V.V.

    1987-01-01

    The reliability and safety of nuclear power plants have decisive meaning under the situation that nuclear power generation steadily increases, and among various measures aiming at ensuring the reliability and safety in the operation of nuclear power plants, the countermeasures for protecting reactor core, main process equipment and high pressure circuits from damage have the important role, and the monitoring of condition and the organization of forecast, which are carried out continuously or periodically during the operation of nuclear power stations using the diagnostic expert system specially developed for the purpose, are included in them. Such monitoring enables the early detection of mechanical damage, increase of vibration, defects caused during operation and so on in reactor cores and primary and secondary circuits, and the continuous watching of defect developments. Also boiling in a core is detected, the place of abnormality occurrence is identified, and the intensity and characteristics of boiling are determined, thus the occurrence of dangerous condition is prevented. The developments of an in-core monitoring system and noise diagnostic systems are reported. (Kako, I.)

  1. Vibration monitoring and fault diagnostics of a thermal power plant

    International Nuclear Information System (INIS)

    Hafeez, T.; Ghani, R.; Chohan, G.Y.; Amir, M.

    2003-01-01

    A thermal power plant was monitored from HP-turbine to the generator end. The vibration data at different plant locations was obtained with the help of a data collector/analyzer. The spectra of-all locations generate the symptoms for different problems of moderate and high vibration levels like bent shaft, misalignment in the exciter rotor and three couplings, mechanical looseness on generator and exciter sides. The possible causes of these faults are discussed on the basis of presented vibration spectra in this paper. The faults were later on rectified on the basis of this diagnostics. (author)

  2. Vibration and noise diagnostics of nuclear power plants Pt. 1

    International Nuclear Information System (INIS)

    Nagy, I.

    1991-01-01

    Development, tasks and methodology of vibration and noise testing of nuclear power plants are overviewed. Reactor noise diagnostics methods are presented and their utilization at various reactors is summarized. Acoustic testing of primary circuit is also considered. Special attention is paid to leak detection and loose parts monitoring by acoustical testing methods. (R.P.) 11 refs.; 18 figs.; 1 tab

  3. Backpropagation architecture optimization and an application in nuclear power plant diagnostics

    International Nuclear Information System (INIS)

    Basu, A.; Bartlett, E.B.

    1993-01-01

    This paper presents a Dynamic Node Architecture (DNA) scheme to optimize the architecture of backpropagation Artificial Neural Networks (ANNs). This network scheme is used to develop an ANN based diagnostic adviser capable of identifying the operating status of a nuclear power plant. Specifically, a root network is trained to diagnose if the plant is in a normal operating condition or not. In the event of an abnormal condition, another classifier network is trained to recognize the particular transient taking place. These networks are trained using plant instrumentation data gathered during simulations of the various transients and normal operating conditions at, the Iowa Electric Light and Power Company's Duane Arnold Energy Center (DAEC) operator training simulator

  4. Backpropagation architecture optimization and an application in nuclear power plant diagnostics

    International Nuclear Information System (INIS)

    Basu, A.; Bartlett, E.B.

    1993-01-01

    This paper presents a Dynamic Node Architecture (DNA) scheme to optimize the architecture of backpropagation Artificial Neural Networks (ANNs). This network scheme is used to develop an ANN based diagnostic adviser capable of identifying the operating status of a nuclear power plant. Specifically, a ''root'' network is trained to diagnose if the plant is in a normal operating condition or not. In the event of an abnormal condition, and other ''classifier'' network is trained to recognize the particular transient taking place. these networks are trained using plant instrumentation data gathered during simulations of the various transients and normal operating conditions at the Iowa Electric Light and Power Company's Duane Arnold Energy Center (DAEC) operator training simulator

  5. The application of artificial intelligence chemistry diagnostic system to nuclear power plants

    International Nuclear Information System (INIS)

    Chen Meizhen

    1996-01-01

    By processing water chemistry data to diagnose sensor and equipment malfunctions in realtime, artificial intelligence chemistry diagnostic system helps to reduce the plant downtime due to steam generator tubing failures and other accidents. A typical processing system of water chemistry data is presented

  6. Experiences with 'on-line' diagnostic instrumentation in nuclear power plants

    International Nuclear Information System (INIS)

    Gopal, R.; Ciaramitaro, W.; Smith, J.R.

    1981-01-01

    Over the past several years, Westinghouse has developed a coordinated system of on-line diagnostic instrumentation for the acquisition and analysis of data for diagnostics and incipient failure detection of critical plant equipment and systems. Primary motivation for this work is to improve Nuclear Steam Supply System (NSSS) availability and maintainability through the detection of malfunctions at their inception. These systems include: 1) Acoustic leak monitoring for detection and location of leaks in the primary system pressure boundary and other piping systems in PWR's; 2) Metal impact monitoring for detection of loose debris in the reactor vessel and steam generators; 3) Nuclear noise monitoring for monitoring core barrel vibration. Summarized in this paper are some of the features of the systems and inplant experience. (author)

  7. Diagnostic study of bovine welfare during transport to a beneficiary plant in the Caribbean region of Colombia

    Directory of Open Access Journals (Sweden)

    Juan Pérez –Viloria

    2017-12-01

    Full Text Available A diagnostic animal welfare (AW study was carried out during the terrestrial transport of cattle to a slaughtering plant in the Caribbean region of Colombia. A cross sectional analytical study was carried out on 20 drivers, evaluating demographic variables, attitude towards cattle and the management. Data of 59 trips (588 cattle were analyzed, evaluating the conditions of the vehicles and determining load density, weight heterogeneity, distance traveled, waiting time before landing and the employee at the landing. Parts of vehicles are not used exclusively for transporting cattle and do not fully comply with the provisions of the ICA. Load densities were lower than those recommended, with values of 320.5 kg/m2 (SD=6.3 and 285.2 kg/m2 (SD=83.48 for small and large vehicles, respectively. Distance traveled was 21.6 km, on average. The average total wait and discharge times were 11.1 and 2.8 min, respectively. The distance traveled, the charge density and the discharge time were correlated with the number of hematomas and the pH of the cold carcass. Failures that have a negative effect on the welfare of cattle during transportation and unloading in the dressing plant and on the quality of the carcass were evidenced, together with the lack of training of the drivers in the AW.

  8. Monitoring and diagnostic system of fission product transport and release in nuclear power plants

    International Nuclear Information System (INIS)

    Kodaira, H.; Kondo, S.; Togo, Y.

    1983-01-01

    A monitoring and diagnostic system (MADS) of fission product (FP) transport and release in nuclear power plants (NPPs) is proposed and the conceptual design for MADS is studied. A MADS can be described in the most general way as a computer-based information processing system which takes in plant data, processes it and displays the results to the NPP's operating crew. A major concern for MADS is, however, not to evaluate general plant dynamics, but to monitor the distribution of whole radioactive materials such as FP, and to diagnose the plant state in the view of FP transport during the NPP's lifetime. Several functions demanded of MADS are: (a) during normal operation, to certify the fuel integrity and the effectiveness of the purification systems, (b) in an unusual event, to identify the event and to monitor the amount of FP release with accuracy, and (c) in case of a rare occurrence, to estimate the maximum potential release

  9. Systematic generation of rules for nuclear power plant diagnostics

    International Nuclear Information System (INIS)

    Reifman, J.; Lee, J.C.

    1988-01-01

    The knowledge base of an expert system is generally represented by a set of heuristic rules derived from the expert's own experience and judgmental knowledge. These heuristic or production rules are cast as if (condition), then (consequence) statements, and represent, for nuclear power plant diagnostic systems, information connecting symptoms to failures. In this paper, the authors apply an entropy minimax pattern recognition algorithm to automate the process of extracting and encoding knowledge into a set of rules. Knowledge is extracted by recognizing patterns in plant parameters or symptoms associated with failures or transient events, and is encoded by casting the discovered patterns as production rules. The paper discusses how the proposed method can systematically generate rules that characterize failure of pressurizer components based on transient events analyzed with a pressurizer components based on transient events analyzed with a pressurizer water reactor simulator program

  10. Development of a computerized system for performance monitoring and diagnostics in nuclear power plants

    International Nuclear Information System (INIS)

    Chou, G.H.; Chao, H.J.

    1995-01-01

    An on-line computerized system for thermal performance monitoring and diagnostics has been developed at the Institute of Nuclear Energy Research (INER). It was the product of the ChinShan plant performance Monitoring, Analysis and Diagnostics Expert System (CS-MADES) project sponsored by Taiwan Power Company (TPC). The system can carry out turbine performance monitoring and analysis during normal operation, and yield diagnostic results of component degradation after finding out the missing generation problems. Three subsystems were generated to support the whole system framework. They are Test Data Processing Subsystem (TDPS), On-line Monitoring and Analysis Subsystem (OMAS), and Thermal Performance Diagnostics Expert System (TPDES). Some visible benefits have been gained so far through the prototype system installed at the Chinshan nuclear power station

  11. Nuclear power plant status diagnostics using a neural network with dynamic node architecture

    International Nuclear Information System (INIS)

    Basu, A.

    1992-01-01

    This thesis is part of an ongoing project at Iowa State University to develop ANN based fault diagnostic systems to detect and classify operational transients at nuclear power plants. The project envisages the deployment of such an advisor at Iowa Electric Light and Power Company's Duane Arnold Energy Center nuclear power plant located at Palo, IA. This advisor is expected to make status diagnosis in real time, thus providing the operators with more time for corrective measures

  12. A qualitative model construction method of nuclear power plants for effective diagnostic knowledge generation

    International Nuclear Information System (INIS)

    Yoshikawa, Shinji; Endou, Akira; Kitamura, Yoshinobu; Sasajima, Munehiko; Ikeda, Mitsuru; Mizoguchi, Riichiro.

    1994-01-01

    This paper discusses a method to construct a qualitative model of a nuclear power plant, in order to generate effective diagnostic knowledge. The proposed method is to prepare deep knowledge to be provided to a knowledge compiler based upon qualitative reasoning (QR). Necessity of knowledge compilation for nuclear plant diagnosis will be explained first, and conventionally-experienced problems in qualitative reasoning and a proposed method to overcome this problem is shown next, then a sample procedure to build a qualitative nuclear plant model is demonstrated. (author)

  13. Nuclear Energy Research Initiative (NERI): On-Line Intelligent Self-Diagnostic Monitoring for Next Generation Nuclear Plants - Phase I Annual Report

    International Nuclear Information System (INIS)

    Bond, L.G.; Doctor, S.R.; Gilbert, R.W.; Jarrell, D.B.; Greitzer, F.L.; Meador, R.J.

    2000-01-01

    OAK-B135 This OSTI ID belongs to an IWO and is being released out of the system. The Program Manager Rebecca Richardson has confirmed that all reports have been received. The objective of this project is to design and demonstrate the operation of the real-time intelligent self-diagnostic and prognostic system for next generation nuclear power plant systems. This new self-diagnostic technology is titled, ''On-Line Intelligent Self-Diagnostic Monitoring System'' (SDMS). This project provides a proof-of-principle technology demonstration for SDMS on a pilot plant scale service water system, where a distributed array of sensors is integrated with active components and passive structures typical of next generation nuclear power reactor and plant systems. This project employs state-of-the-art sensors, instrumentation, and computer processing to improve the monitoring and assessment of the power reactor system and to provide diagnostic and automated prognostics capabilities

  14. Diagnostic aid and maintenance at the La Hague reprocessing plants

    International Nuclear Information System (INIS)

    Bern, J.B.; Chabert, J.

    1989-01-01

    The Cogema plant at La Hague is the world's leading nuclear fuel reprocessing plant. A major extension program was initiated in 1980. It includes the construction of a new 800 t/year capacity plant (UP3), to be commissioned in 1989, and the doubling of the capacity of the present plant (UP2 800) scheduled to go on stream in 1992. On the occasion of this huge capital investment, an overall assessment was made of the operating and maintenance systems of the site. The general objective was to achieve maximum productivity and availability, in view of: - the extreme importance of safety for the protection of workers and the environment, - the high level of automation required by the complexity of the process, - the inaccessibility of the nuclear equipment, the scale of the investment. To achieve this goal, a set of diagnostic and maintenance aid systems were developed and installed. A general site data network serves to link these systems and to distribute the corresponding data to the different users. This paper describes these different systems, presents the functionalities of the network and demonstrates the sequencing of the operations in a typical maintenance application

  15. Applications of laser diagnostics to thermal power plants and engines

    International Nuclear Information System (INIS)

    Deguchi, Y.; Kamimoto, T.; Wang, Z.Z.; Yan, J.J.; Liu, J.P.; Watanabe, H.; Kurose, R.

    2014-01-01

    The demands for lowering the burdens on the environment will continue to grow steadily. It is important to monitor controlling factors in order to improve the operation of industrial thermal systems. In engines, exhaust gas temperature and concentration distributions are important factors in nitrogen oxides (NO x ), total hydrocarbon (THC) and particulate matter (PM) emissions. Coal and fly ash contents are parameters which can be used for the control of coal-fired thermal power plants. Monitoring of heavy metals such as Hg is also important for pollution control. In this study, the improved laser measurement techniques using computed tomography-tunable diode laser absorption spectroscopy (CT-TDLAS), low pressure laser-induced breakdown spectroscopy (LIBS), and laser breakdown time-of-flight mass spectrometry (LB-TOFMS) have been developed and applied to measure 2D temperature and species concentrations in engine exhausts, coal and fly ash contents, and trace species measurement. The 2D temperature and NH 3 concentration distributions in engine exhausts were successfully measured using CT-TDLAS. The elemental contents of size-segregated particles were measured and the signal stability increased using LIBS with the temperature correction method. The detection limit of trace species measurement was enhanced using low pressure LIBS and LB-TOFMS. The detection limit of Hg can be enhanced to 3.5 ppb when employing N 2 as the buffer gas using low pressure LIBS. Hg detection limit was about 0.82 ppb using 35 ps LB-TOFMS. Compared to conventional measurement methods laser diagnostics has high sensitivity, high response and non-contact features for actual industrial systems. With these engineering developments, transient phenomena such as start-ups in thermal systems can be evaluated to improve the efficiency of these thermal processes. - Highlights: • Applicability of newly developed laser diagnostics was demonstrated for the improvement of thermal power plants and

  16. Nuclear Energy Research Initiative (NERI): On-Line Intelligent Self-Diagnostic Monitoring for Next Generation Nuclear Plants - Phase I Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    L. J. Bond; S. R. Doctor; R. W. Gilbert; D. B. Jarrell; F. L. Greitzer; R. J. Meador

    2000-09-01

    OAK-B135 This OSTI ID belongs to an IWO and is being released out of the system. The Program Manager Rebecca Richardson has confirmed that all reports have been received. The objective of this project is to design and demonstrate the operation of the real-time intelligent self-diagnostic and prognostic system for next generation nuclear power plant systems. This new self-diagnostic technology is titled, ''On-Line Intelligent Self-Diagnostic Monitoring System'' (SDMS). This project provides a proof-of-principle technology demonstration for SDMS on a pilot plant scale service water system, where a distributed array of sensors is integrated with active components and passive structures typical of next generation nuclear power reactor and plant systems. This project employs state-of-the-art sensors, instrumentation, and computer processing to improve the monitoring and assessment of the power reactor system and to provide diagnostic and automated prognostics capabilities.

  17. Software for the diagnostic system of the secondary circuit of the Temelin nuclear power plant

    International Nuclear Information System (INIS)

    Drab, J.

    1990-01-01

    The secondary circuit of unit 1 of the Temelin nuclear power plant will be fitted with an automated diagnostic system, whose objects include the turbine and generator; feedwater pumps and their turbines; separator-reheater; condensers; low-pressure and high-pressure heaters; feedwater tank; and steam lines. The automated diagnostic system is divided into 5 subsystems, each containing a measuring unit controlled by a PC 286 computer. These computers are included in a LAN network with a PC 386 master computer. The software consists of 3 components, viz. ONSPEC for controlling the measuring unit, data evaluation and organization and for intercommunication within the LAN; diagnostic software for the diagnostic tests, of which a total of 23 are included; and communication software for transmitting the diagnostic test results to the unit control room and also for transmitting data from accurate sensors to the information computer system for technico-economic calculations. The whole system is open to future supplementing with additional software, diagnostic tests or diagnostic subsystems. (P.A.). 1 fig., 3 refs

  18. How does a change in the control room design affect diagnostic strategies in nuclear power plants?

    International Nuclear Information System (INIS)

    Kim, Dong Young; Kim, Jonghyun

    2014-01-01

    Recently, main control rooms have been considerably changed by modern computer techniques. Some of the features that distinguish digital control rooms from conventional, analog rooms in nuclear power plants include advanced alarm systems, graphic information display systems, computerized procedure systems, and soft control. These features can bring changes in operator tasks, changing the characteristics of tasks or creating new tasks for operators. It is especially expected that these features may bring out changes in the operator's diagnostic tasks and strategies in a digital control room as compared with an analog control room. This study investigates the differences in the operator's diagnostic tasks and strategies in analog and digital control rooms. This study also attempts to evaluate how new systems in a digital control room affect diagnostic strategies. Three different approaches, which are complementary, are used to identify diagnostic strategies in the digital control room and in the analog control room: (1) observation in the simulator, (2) interview with operators, and (3) a literature review. The results show that the digital control room introduces new diagnosis strategies compared with the analog control room while also changing the characteristics of the strategies, mostly by gaining more support from the computerized system. (author)

  19. DIVA and DIAPO: two diagnostic knowledge based systems used for French nuclear power plants

    International Nuclear Information System (INIS)

    Porcheron, M.; Ricard, B.; Joussellin, A.

    1997-01-01

    In order to improve monitoring and diagnosis capabilities in nuclear power plants, Electricite de France (EDF) has designed an integrated monitoring and diagnosis assistance system: PSAD-Poste de Surveillance et d'Aide au Diagnostic. The development of such a sophisticated monitoring and data processing systems has emphasized the need for the addition of analysis and diagnosis assistance capabilities. Therefore, diagnostic knowledge based systems have been added to the functions monitored in PSAD: DIVA for turbine generators, and DIAPO for reactor coolant pumps. These systems were designed from a representation of the diagnostic reasoning process of experts and of the supporting knowledge. Diagnosis in both systems relies on an abduction reasoning process applied to component fault models and observations derived from their actual behavior, as provided by the monitoring functions. The basic theoretical elements of this diagnostic model are summarized in a first part. In a second part, DIVA and DIAPO specific elements are described

  20. Simulation study of a system for diagnosis of nuclear power plant operation

    International Nuclear Information System (INIS)

    Wakabayashi, J.; Fukumoto, A.

    1981-01-01

    A diagnostic system of the nuclear power plant operation is proposed and the applicability of this system to the actual plant has been verified by computer simulation. A typical pressurized water reactor plant simulator was made by an analog computer and the diagnostic system was made by a digital computer. The observed signals obtained from the actual plant are simulated by superposing the equivalent observation noises generated by the digital computer on the sampled signals obtained from the plant simulator. 8 refs

  1. Development of an integrated condition monitoring and diagnostic system for motor-operated valves used in nuclear power plant

    International Nuclear Information System (INIS)

    Carneiro, Alvaro Luiz Guimaraes

    2003-01-01

    The reliability question of the components, specifically of motor operated valves, became one of the most important issues to be investigated in nuclear power plants, considering security and life plant extension. Therefore, the necessity of improvements in monitoring and diagnosis methods started to be of extreme relevance in the maintenance predictive field, establishing as main goal the reliability and readiness of the system components. Specially in nuclear power plants, the predictive maintenance contributes in the security factor in order to diagnosis in advance the occurrence of a possible failure, preventing severe situations. It also presents a contribution on the economic side by establishing a better maintenance programming, and reducing unexpected shutdown. The development of non intrusive monitoring and diagnostic method makes it possible to identify malfunctions in plant components during normal plant operation. This dissertation presents the development of an integrated condition monitoring system for motor-operated valves used in nuclear power plants. The methodology used in this project is based on the electric motor power signatures analysis, during the closing and opening stroke time of the valve. Once the measurements baseline diagnostic of the motor-operated valve is taken, it is possible to detect long-term deviations during valve lifetime, detecting in advance valve failures. The system implements two parallel techniques for detection and categorization of anomalies: expert system using fuzzy logic based on rules and knowledge base, providing a systematic approach for decision making, and the Wavelet Transform Technique, where the main goal is to obtain more detailed information contained in the measured data, identifying and characterizing the transients phenomena in the time and frequency domains, correlating them to failures situations in the incipient stage. The conditioning monitoring and diagnostic system was designed and implemented at

  2. Water chemistry data acquisition, processing, evaluation and diagnostic systems in Light Water Reactors: Future improvement of plant reliability and safety

    International Nuclear Information System (INIS)

    Uchida, S.; Takiguchi, H.; Ishigure, K.

    2006-01-01

    Data acquisition, processing and evaluation systems have been applied in major Japanese PWRs and BWRs to provide (1) reliable and quick data acquisition with manpower savings in plant chemical laboratories and (2) smooth and reliable information transfer among chemists, plant operators, and supervisors. Data acquisition systems in plants consist of automatic and semi-automatic instruments for chemical analyses, e. g., X-ray fluorescence analysis and ion chromatography, while data processing systems consist of PC base-sub-systems, e.g., data storage, reliability evaluation, clear display, and document preparation for understanding the plant own water chemistry trends. Precise and reliable evaluations of water chemistry data are required in order to improve plant reliability and safety. For this, quality assurance of the water chemistry data acquisition system is needed. At the same time, theoretical models are being applied to bridge the gaps between measured water chemistry data and the information desired to understand the interaction of materials and cooling water in plants. Major models which have already been applied for plant evaluation are: (1) water radiolysis models for BWRs and PWRs; (2) crevice radiolysis model for SCC in BWRs; and (3) crevice pH model for SG tubing in PWRs. High temperature water chemistry sensors and automatic plant diagnostic systems have been applied in only restricted areas. ECP sensors are gaining popularity as tools to determine the effects of hydrogen injection in BWR systems. Automatic plant diagnostic systems based on artificial intelligence will be more popular after having sufficient experience with off line diagnostic systems. (author)

  3. User interface graphically improves generator AL diagnostics

    International Nuclear Information System (INIS)

    Gray, R.F.; King, I.J.

    1991-01-01

    In April of 1990, the recently developed Diagnostic Graphical User Interface (DGUI) was installed at a large nuclear power plant in the midwestern United States. Since 1988, the power plant has been using the Generator Artificial Intelligence Diagnostics (GenAID) System, which provides online diagnostic capability for the generator and generator auxiliaries through a plant data center (PDC) and communication link to the diagnostic operations center (DOC) in Orlando, Florida. The enhanced system provides the power plant control room operator with a comprehensive tool to understand and better utilize the information provided by the existing knowledge bases. This paper represents a significant improvement over existing technology by providing the power plant control room operator with the capability of interacting directly with the diagnostic system

  4. EEG Analysis during complex diagnostic tasks in Nuclear Power Plants - Simulator-based Experimental Study

    Energy Technology Data Exchange (ETDEWEB)

    Ha, Jun Su; Seong, Poong Hyun [Korea Advanced Institute of Science and Technology, Taejon (Korea, Republic of)

    2005-07-01

    In literature, there are a lot of studies based on EEG signals during cognitive activities of human-beings but most of them dealt with simple cognitive activities such as transforming letters into Morse code, subtraction, reading, semantic memory search, visual search, memorizing a set of words and so on. In this work, EEG signals were analyzed during complex diagnostic tasks in NPP simulator-based environment. Investigated are the theta, alpha, beta, and gamma band EEG powers during the diagnostic tasks. The experimental design and procedure are represented in section 2 and the results are shown in section 3. Finally some considerations are discussed and the direction for the further work is proposed in section 4.

  5. EEG Analysis during complex diagnostic tasks in Nuclear Power Plants - Simulator-based Experimental Study

    International Nuclear Information System (INIS)

    Ha, Jun Su; Seong, Poong Hyun

    2005-01-01

    In literature, there are a lot of studies based on EEG signals during cognitive activities of human-beings but most of them dealt with simple cognitive activities such as transforming letters into Morse code, subtraction, reading, semantic memory search, visual search, memorizing a set of words and so on. In this work, EEG signals were analyzed during complex diagnostic tasks in NPP simulator-based environment. Investigated are the theta, alpha, beta, and gamma band EEG powers during the diagnostic tasks. The experimental design and procedure are represented in section 2 and the results are shown in section 3. Finally some considerations are discussed and the direction for the further work is proposed in section 4

  6. Simulation-based diagnostics and control for nuclear power plants. Final report, April 15, 1992--April 14, 1995

    International Nuclear Information System (INIS)

    Lee, J.C.

    1995-07-01

    The objective of the project was to develop and test a simulation-based diagnostics and control guidance system that can be used to diagnose and manage off-normal transient events in nuclear power plants. The research has focused on developing two diagnostic approaches suitable for detection and identification of faults involving multiple components, subject to uncertainties in system modeling and observations. The first approach is based on a fuzzy logic framework that can diagnose binary failures using a single-failure diagnostic knowledge base. Construction of the binary-failure knowledge base is accomplished through the use of macroscopic conservation relationships and a fuzzy inference structure is developed to determine the magnitude of faults and the associated certainty. In the second diagnostic approach, an adaptive Kalman filter algorithm is derived to yield information on the type and magnitude of feasible component transitions that can account for system observations. To obtain the likelihood of feasible component failures or degradations, a general probabilistic formulation is developed where statistical distributions associated with component reliability data are explicitly represented. Testing of the diagnostic algorithms has been performed through the analysis of simulated transient events for light water reactor systems. Preliminary studies have been conducted to develop Monte Carlo algorithms for flexible control of transient events

  7. Power plant experience with artificial intelligence based, on-line diagnostic systems

    International Nuclear Information System (INIS)

    Osborne, R.L.; Coffman, M.

    1987-01-01

    The utility industry is entering a period when generation equipment availability becomes increasingly critical due to the lack of new power plants being planned and built. The increasing percentage of all electric homes adding to peak demands requires more plant equipment to be used in a cyclic duty mode. Availability is on the increase with forced and planned maintenance hours decreasing. Factors that are contributing to this improvement are new units coming on-line with the latest in technology coupled with the installation of retrofit components containing that same technology such as the Rigi-Flex generators and ruggedized turbine rotors. In conjunction with hardware advances, technology advancements in monitoring and diagnostics are permitting the identification of potential malfunctions so that corrective actions can be taken, thus preventing lengthy outages. It is this last area that this paper will address

  8. Artificial intelligence applications to the surveillance and diagnostics of nuclear power plants

    International Nuclear Information System (INIS)

    Zwingelstein, G.; Monnier, B.

    1985-01-01

    Artificial intelligence has come of age; it can be applied with benefits in the nuclear industry for various applications to improve both plant safety and availability. This paper presents four rule-based expert systems currently under development at Electricite de France for the surveillance and the diagnostics of pressurized water reactors (PWRs). The objectives of these experiences with expert system projects are to demonstrate their feasibility, to provide an evaluation of their potential benefits through on-site implementation, to identify the problems due to the knowledge extraction and representation, and finally to specify the classes of problems where expert systems are needed and useful. The specific goals of these expert systems are to provide an aid for the detection and location of failures occurring in nuclear plants

  9. Study on fault diagnostic system using modularized knowledge; Mojuru gata chishiki wo mochiita ijo shindan system ni kansuru kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    Shimada, Y.; Sayama, H.; Suzuki, K. [Okayama Univ. (Japan). Dept. of Industrial and Mechanical Engineering

    1997-08-15

    Recently, a fault diagnostic expert system was prosperously developed as an objective of chemical plants and nuclear power plants. In this paper, a fault diagnostic method using modularized knowledge was proposed, a fault diagnostic system was constructed for an experimental plant, and the effectiveness of this method was clarified by carrying out a fault diagnostic experiment. The characteristics of the proposed fault diagnostic system were as follows: The necessary knowledge for diagnosing faults was made into each process element. Based on this method, the revision and addition of a knowledge base could be carried out in each element, and the design change of a plant could be flexibly corresponded by only changing the related part of the process flow graph. The estimated results were stored into the working memory, not only faults of an element in which faults resulted could be estimated, but also the fault propagating path could be clarified. 8 refs., 6 figs., 3 tabs.

  10. Vital Autofluorescence: Application to the Study of Plant Living Cells

    Directory of Open Access Journals (Sweden)

    Victoria V. Roshchina

    2012-01-01

    approach to study the autofluorescence of plant living cells—from cell diagnostics up to modelling the cell-cell contacts and cell interactions with fluorescent biologically active substances. It bases on the direct observations of secretions released from allelopathic and medicinal species and the cell-donor interactions with cell-acceptors as biosensors (unicellular plant generative and vegetative microspores. Special attention was paid to the interactions with pigmented and fluorescing components of the secretions released by the cells-donors from plant species. Colored components of secretions are considered as histochemical dyes for the analysis of cellular mechanisms at the cell-cell contacts and modelling of cell-cell interactions. The fluorescence of plant biosensors was also recommended for the testing of natural plant excretions as medical drugs.

  11. CBDS: Constraint-based diagnostic system for malfunction identification in the nuclear power plant

    International Nuclear Information System (INIS)

    Ha, J.

    1992-01-01

    Traditional rule-based diagnostic expert systems use the experience of experts in the form of rules that associate symptoms with underlying faults. A commonly recognized failing of such systems is their narrow range of expertise and their inability to recognize problems outside this range of expertise. A model base diagnostic system isolating malfunctioning components-CBDS, the Constraint based Diagnostic System-has been developed. Since the intended behavior of a device is more predictable than unintended behaviors (faults), a model based system using the intended behavior has a potential to diagnose unexpected malfunctions by considering faults as open-quotes anything other than the intended behavior.close quotes As a knowledge base, the CBDS generates and decomposes a constraint network based on the structure and behavior model, which are represented symbolically in algebraic equations. Behaviors of generic components are organized in a component model library. Once the library is available, actual domain knowledge can be represented by declaring component types and their connections. To capture various plant knowledge, the mixed model was developed which allow the use of different parameter types in one equation by defining various operators. The CBDS uses the general idea of model based diagnosis. It detects a discrepancy between observation and prediction using constraint propagation, which carriers and accumulates the assumptions when parameter values are deduced. When measured plant parameters are asserted into a constraint network and are propagated through the network, a discrepancy will be detected if there exists any malfunctioning component. The CBDS was tested in the Recirculation Flow Control System of a BWR, and has been shown to be able to diagnose unexpected events

  12. A diagnostic expert system for the nuclear power plant b ased on the hybrid knowledge approach

    International Nuclear Information System (INIS)

    Yang, J.O.; Chang, S.H.

    1989-01-01

    A diagnostic expert system, the hybrid knowledge based plant operation supporting system (HYPOSS), which has been developed to support operators' decisionmaking during the transients of the nuclear power plant, is described. HYPOSS adopts the hybrid knowledge approach, which combines both shallow and deep knowledge to take advantage of the merits of both approaches. In HYPOSS, four types of knowledge are used according to the steps of diagnosis procedure. They are structural, functional, behavioral, and heuristic knowledge. The structural and functional knowledge is represented by three fundamental primitives and five types of functions, respectively. The behavioral knowledge is represented using constraints. The inference procedure is based on the human problem-solving behavior modeled in HYPOSS. The event-based operational guidelines are provided to the operator according to the diagnosed results. If the exact anomalies cannot be identified while some of the critical safety functions are challenged, the function-based operational guidelines are provided to the operator. For the validation of HYPOSS, several tests have been performed based on the data produced by a plant simulator. The results of validation studies show good applicability of HYPOSS to the anomaly diagnosis of nuclear power plant

  13. Viral Diagnostics in Plants Using Next Generation Sequencing: Computational Analysis in Practice

    Directory of Open Access Journals (Sweden)

    Susan Jones

    2017-10-01

    Full Text Available Viruses cause significant yield and quality losses in a wide variety of cultivated crops. Hence, the detection and identification of viruses is a crucial facet of successful crop production and of great significance in terms of world food security. Whilst the adoption of molecular techniques such as RT-PCR has increased the speed and accuracy of viral diagnostics, such techniques only allow the detection of known viruses, i.e., each test is specific to one or a small number of related viruses. Therefore, unknown viruses can be missed and testing can be slow and expensive if molecular tests are unavailable. Methods for simultaneous detection of multiple viruses have been developed, and (NGS is now a principal focus of this area, as it enables unbiased and hypothesis-free testing of plant samples. The development of NGS protocols capable of detecting multiple known and emergent viruses present in infected material is proving to be a major advance for crops, nuclear stocks or imported plants and germplasm, in which disease symptoms are absent, unspecific or only triggered by multiple viruses. Researchers want to answer the question “how many different viruses are present in this crop plant?” without knowing what they are looking for: RNA-sequencing (RNA-seq of plant material allows this question to be addressed. As well as needing efficient nucleic acid extraction and enrichment protocols, virus detection using RNA-seq requires fast and robust bioinformatics methods to enable host sequence removal and virus classification. In this review recent studies that use RNA-seq for virus detection in a variety of crop plants are discussed with specific emphasis on the computational methods implemented. The main features of a number of specific bioinformatics workflows developed for virus detection from NGS data are also outlined and possible reasons why these have not yet been widely adopted are discussed. The review concludes by discussing the future

  14. Viral Diagnostics in Plants Using Next Generation Sequencing: Computational Analysis in Practice.

    Science.gov (United States)

    Jones, Susan; Baizan-Edge, Amanda; MacFarlane, Stuart; Torrance, Lesley

    2017-01-01

    Viruses cause significant yield and quality losses in a wide variety of cultivated crops. Hence, the detection and identification of viruses is a crucial facet of successful crop production and of great significance in terms of world food security. Whilst the adoption of molecular techniques such as RT-PCR has increased the speed and accuracy of viral diagnostics, such techniques only allow the detection of known viruses, i.e., each test is specific to one or a small number of related viruses. Therefore, unknown viruses can be missed and testing can be slow and expensive if molecular tests are unavailable. Methods for simultaneous detection of multiple viruses have been developed, and (NGS) is now a principal focus of this area, as it enables unbiased and hypothesis-free testing of plant samples. The development of NGS protocols capable of detecting multiple known and emergent viruses present in infected material is proving to be a major advance for crops, nuclear stocks or imported plants and germplasm, in which disease symptoms are absent, unspecific or only triggered by multiple viruses. Researchers want to answer the question "how many different viruses are present in this crop plant?" without knowing what they are looking for: RNA-sequencing (RNA-seq) of plant material allows this question to be addressed. As well as needing efficient nucleic acid extraction and enrichment protocols, virus detection using RNA-seq requires fast and robust bioinformatics methods to enable host sequence removal and virus classification. In this review recent studies that use RNA-seq for virus detection in a variety of crop plants are discussed with specific emphasis on the computational methods implemented. The main features of a number of specific bioinformatics workflows developed for virus detection from NGS data are also outlined and possible reasons why these have not yet been widely adopted are discussed. The review concludes by discussing the future directions of this

  15. Diagnostic and prognostic system for identification of accident scenarios and prediction of 'source term' in nuclear power plants under accident conditions

    International Nuclear Information System (INIS)

    Santhosh; Gera, B.; Kumar, Mithilesh

    2014-01-01

    Nuclear power plant experiences a number of transients during its operations. These transients may be due to equipment failure, malfunctioning of process support systems etc. In such a situation, the plant may result in an abnormal state which is undesired. In case of such an undesired plant condition, the operator has to carry out diagnostic and corrective actions. When an event occurs starting from the steady state operation, instruments' readings develop a time dependent pattern and these patterns are unique with respect to the type of the particular event. Therefore, by properly selecting the plant process parameters, the transients can be distinguished. In this connection, a computer based tool known as Diagnostic and Prognostic System has been developed for identification of large pipe break scenarios in 220 MWe Pressurised Heavy Water Reactors (PHWRs) and for prediction of expected 'Source Term' and consequence for a situation where Emergency Core Cooling System (ECCS) is not available or partially available. Diagnostic and Prognostic System is essentially a transient identification and expected source term forecasting system. The system is based on Artificial Neural Networks (ANNs) that continuously monitors the plant conditions and identifies a Loss Of Coolant Accident (LOCA) scenario quickly based on the reactor process parameter values. The system further identifies the availability of injection of ECCS and in case non-availability of ECCS, it can forecast expected 'Source Term'. The system is a support to plant operators as well as for emergency preparedness. The ANN is trained with a process parameter database pertaining to accident conditions and tested against blind exercises. In order to see the feasibility of implementing in the plant for real-time diagnosis, this system has been set up on a high speed computing facility and has been demonstrated successfully for LOCA scenarios. (author)

  16. Automated diagnostics scoping study. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Quadrel, R.W.; Lash, T.A.

    1994-06-01

    The objective of the Automated Diagnostics Scoping Study was to investigate the needs for diagnostics in building operation and to examine some of the current technologies in automated diagnostics that can address these needs. The study was conducted in two parts. In the needs analysis, the authors interviewed facility managers and engineers at five building sites. In the technology survey, they collected published information on automated diagnostic technologies in commercial and military applications as well as on technologies currently under research. The following describe key areas that the authors identify for the research, development, and deployment of automated diagnostic technologies: tools and techniques to aid diagnosis during building commissioning, especially those that address issues arising from integrating building systems and diagnosing multiple simultaneous faults; technologies to aid diagnosis for systems and components that are unmonitored or unalarmed; automated capabilities to assist cause-and-effect exploration during diagnosis; inexpensive, reliable sensors, especially those that expand the current range of sensory input; technologies that aid predictive diagnosis through trend analysis; integration of simulation and optimization tools with building automation systems to optimize control strategies and energy performance; integration of diagnostic, control, and preventive maintenance technologies. By relating existing technologies to perceived and actual needs, the authors reached some conclusions about the opportunities for automated diagnostics in building operation. Some of a building operator`s needs can be satisfied by off-the-shelf hardware and software. Other needs are not so easily satisfied, suggesting directions for future research. Their conclusions and suggestions are offered in the final section of this study.

  17. Knowledge based diagnostics in nuclear power plants

    International Nuclear Information System (INIS)

    Baldeweg, F.; Fiedler, U.; Weiss, F.P.; Werner, M.

    1987-01-01

    In this paper a special process diagnostic system (PDS) is presented. It must be seen as the result of a long term work on computerized process surveillance and control; it includes a model based system for noise analysis of mechanical vibrations, which has recently been enhanced by using of knowledge based technique (expert systems). The paper discusses the process diagnostic frame concept and emphasize the vibration analysis expert system

  18. Molecular diagnostics in plant health

    NARCIS (Netherlands)

    Bonants, P.J.M.; Witt, te René

    2017-01-01

    In several crops, their quality and condition is very important. The products are relatively expensive and plant diseases can destroy valuable harvests in a very short time. The presence or absence of plant pathogens and pests, therefore, needs to be accurately tested. For decades, identification

  19. DNA barcoding for biosecurity: case studies from the UK plant protection program.

    Science.gov (United States)

    Hodgetts, Jennifer; Ostojá-Starzewski, Jozef C; Prior, Thomas; Lawson, Rebecca; Hall, Jayne; Boonham, Neil

    2016-11-01

    Since its conception, DNA barcoding has seen a rapid uptake within the research community. Nevertheless, as with many new scientific tools, progression towards the point of routine deployment within diagnostic laboratories has been slow. In this paper, we discuss the application of DNA barcoding in the Defra plant health diagnostic laboratories, where DNA barcoding is used primarily for the identification of invertebrate pests. We present a series of case studies that demonstrate the successful application of DNA barcoding but also reveal some potential limitations to expanded use. The regulated plant pest, Bursephalenchus xylophilus, and one of its vectors, Monochamus alternatus, were found in dining chairs. Some traded wood products are potentially high risk, allowing the movement of longhorn beetles; Trichoferus campestris, Leptura quadrifasciata, and Trichoferus holosericeus were found in a wooden cutlery tray, a railway sleeper, and a dining chair, respectively. An outbreak of Meloidogyne fallax was identified in Allium ampeloprasum and in three weed species. Reference sequences for UK native psyllids were generated to enable the development of rapid diagnostics to be used for monitoring following the release of Aphalara itadori as a biological control agent for Fallopia japonica.

  20. Implementing artificial neural networks in nuclear power plants diagnostic systems: issues and challenges

    International Nuclear Information System (INIS)

    Boger, Z.

    1998-01-01

    A recent review of artificial intelligence applications in nuclear power plants (NPP) diagnostics and fault detection finds that mostly expert systems (ES) and artificial neural networks (ANN) techniques were researched and proposed, but the number of actual implementations in NPP diagnostics systems is very small. It lists the perceived obstacles to the ANN-based system acceptance and implementation. This paper analyses this list. Some of ANN limitations relate to 'quantitative' difficulties of designing and training large-scale ANNs. The availability of an efficient large-scale ANN training algorithm may alleviate most of these concerns. Other perceived drawbacks refer to the 'qualitative' aspects of ANN acceptance - how and when can we rely on the quality of the advice given by the ANN model. Several techniques are available that help to brighten the 'black box' image of the ANN. Analysis of the trained ANN can identify the significant inputs. Calculation of the Causal Indices may reveal the magnitude and sign of the influence of each input on each output. Both these techniques increase the confidence of the users when they conform to known knowledge, or point to plausible relationships. Analysis of the behavior of the neurons in the hidden layer can identify false ANN classification when presented with noisy or corrupt data. Auto-associative NN can identify faulty sensors or data. Two examples of the ANN capabilities as possible diagnostic tools are given, using NPP data, one classifying internal reactor disturbances by neutron noise spectra analysis, the other identifying the faults causes of several transients. To use these techniques the ANN developers need large amount of training data of as many transients as possible. Such data is routinely generated in NPP simulators during the periodic qualification of NPP operators. The IAEA can help by encouraging the saving and distributing the transient data to developers of ANN diagnostic system, to serve as

  1. Diagnostic radiography: A study in distancing

    International Nuclear Information System (INIS)

    Reeves, Pauline J.; Decker, Sola

    2012-01-01

    Aims: This article aims to explore the ways in which diagnostic radiographers use distancing as a tool for emotional management in radiography practice. Methods: This review utilises data from oral history interviews undertaken as part of a larger study documenting the oral history of the diagnostic radiography profession in the United Kingdom as recounted by 24 participants. Results: The results are presented as illustrative of various aspects of the role of the diagnostic radiographer including the initial choice of diagnostic radiography as a profession, the endemic use of particular terminology, the nature of the encounter in diagnostic radiography (including that of sectional imaging) and whether the role is really patient-centred. Conclusions: The article concludes by suggesting that distancing from the patient is mediated by the need for physical touch in order to position the patient for radiography and also makes the suggestion that those opting for diagnostic radiography as a career may do so because they want a profession which is more distanced from the patient and that, even where this is not the case initially, individuals are socialised into adopting the ‘feeling rules’ of the profession. The article concludes by outlining potential areas for further research.

  2. Application study of non-linear reasoning for nuclear plant operation

    International Nuclear Information System (INIS)

    Yoshikawa, Shinji; Yonekawa, Tsuyoshi; Suda, Kazunori; Hasegawa, Makoto

    1999-03-01

    Achievement of improved operation safety of complex nuclear power plants by decision-making functions based on information processing technologies requires real time concluding to be in-time for plant state evolutions, transparency for human operators to understand the derived conclusion, and robustness against local defects inevitably hidden in huge amount of the referred information. These requirements can not be met by the simple rule-based reasoning. The study introduced in this report put a focus on the robustness of the three requirements. This study derives the required feature of robust decision making, after thinking of possible contribution of fast emerging measurement technologies. Finally, two concrete algorithm based on mutual evaluation of relatively simple diagnostic modules are implemented on computer systems and evaluated in views of applicability. (author)

  3. Nuclear power plant diagnostics

    International Nuclear Information System (INIS)

    Hollo, E.; Siklossy, P.

    1982-01-01

    The cooling circuit vibration diagnostic system of the Block 1 of the Paks nuclear power station is described. The automatic online vibration monitoring system consisting presently of 42 acceleration sensors and 9 pressure fluctuation sensors, which could be extended, performs both global and local inspection of the primary cooling circuit and its components. The offline data processing system evaluates the data for failure mode analysis. The software under development will be appropriate for partial preliminary identification of failure reasons during their initial phases. The installation experiences and the preliminary results during the hot operational testing of Block 1 are presented. (Sz.J.)

  4. A diagnostic methodology for refrigerating systems; Methodologie de diagnostic des installations frigorifiques

    Energy Technology Data Exchange (ETDEWEB)

    Vrinat, G. [Association Francaise du Froid (AFF), 75 - Paris (France)

    1997-12-31

    A diagnostic methodology for refrigerating machines, equipment and plants has been defined and evaluated for EDF, the French national power utility and ADEME, the French Agency for Energy Conservation, in the framework of energy conservation objectives: the diagnostic method should enable to identify malfunctions, assess the cost efficiency of the equipment, identify limiting factors, and consider corrective measures

  5. Detection and Diagnostics of Plant Pathogens

    NARCIS (Netherlands)

    Gullino, M.L.; Bonants, P.J.M.

    2014-01-01

    This book is part of the Plant Pathology in the 21st Century Series, started in the occasion of the IX International Congress of Plant Pathology, Torino, 2008. In conjunction with the Xth International Congress of Plant Pathology, held in Beijing in August 2013. Although deriving from a Congress,

  6. A flexible simulator for training an early fault diagnostic system

    International Nuclear Information System (INIS)

    Marsiletti, M.; Santinelli, A.; Zuenkov, M.; Poletykin, A.

    1997-01-01

    An early fault diagnostic system has been developed addressed to timely trouble shooting in process plants during any operational modes. The theory of this diagnostic system is related with the usage of learning methods for automatic generation of knowledge bases. This approach enables the conversion of ''cause→effect'' relations into ''effect→possible-causes'' ones. The diagnostic rules are derived from the operation of a plant simulator according to a specific procedure. Flexibility, accuracy and high speed are the major characteristics of the training simulator, used to generate the diagnostic knowledge base. The simulator structure is very flexible, being based on LEGO code but allowing the use of practically any kind of FORTRAN routines (recently also ACSL macros has been introduced) as plant modules: this permits, when needed, a very accurate description of the malfunctions the diagnostic system should ''known''. The high speed is useful to shorten the ''learning'' phase of the diagnostic system. The feasibility of the overall system has been assessed, using as reference plant the conventional Sampierdarena (Italy) power station, that is a combined cycle plant dedicated to produce both electrical and heat power. The hardware configuration of this prototype system was made up of a network of a Hewlett-Packard workstation and a Digital VAX-Station. The paper illustrates the basic structure of the simulator used for this diagnostic system training purpose, as well as the theoretical background on which the diagnostic system is based. Some evidence of the effectiveness of the concept through the application to Sampierdarena 40 MW cogeneration plant is reported. Finally an outline of an ongoing application to a WWER-1000 plant is given; the operating system is, in this case, UNIX. (author)

  7. Electron beam diagnostics study

    International Nuclear Information System (INIS)

    Garganne, P.

    1989-08-01

    This paper summarizes the results of a study on beam diagnostics, using carbon wire scanners and optical transition radiation (DTR) monitors. The main consideration consists in the material selection, taking their thermal properties and their effect on the beam into account [fr

  8. Diagnostic studies in amyloidosis

    NARCIS (Netherlands)

    Hazenberg, Bouke Pier Cornelis

    2007-01-01

    In this thesis two diagnostic techniques are studied in amyloidosis. Systemic amyloidosis is characterized by deposition of amyloid fibrils (tiny fibres) throughout the body resulting in damage of vital organs. Amyloid can be detected in a tissue specimen stained with Congo red: red-stained amyloid

  9. Application of diagnostic system for diesel engine

    International Nuclear Information System (INIS)

    Yoshinaga, Takeshi; Hayashi, Haruji; Usui, Hiromi; Tsuruzono, Atsuya; Matsuda, Takafumi

    2008-01-01

    The Japan Atomic Power Company (JAPC) began to implement Condition Based Maintenance (CBM) for rotating components (pumps, fans and electric motors) from 1999 and, also has begun to apply diesel engine diagnostic techniques at our three nuclear power plants since 2004. This paper provides a description of the CBM methods used for diesel engines in nuclear standby service, a summary of the procedures to introduce these diagnostic techniques to our nuclear power plants, and experience with the application of these methods to JAPC nuclear power plants. (author)

  10. Data processing technologies and diagnostics for water chemistry and corrosion control in nuclear power plants (DAWAC). Report of a coordinated research project 2001-2005

    International Nuclear Information System (INIS)

    2006-06-01

    This publication provides information on the current status and development trends in monitoring, diagnostics and control of water chemistry and corrosion of core and primary circuit materials in water cooled power reactors. It summarizes the results of an IAEA Coordinated Research Project and focuses on the methods for development, qualification and implementation of water chemistry expert systems at nuclear power plants. These systems are needed to have full benefit from using on-line sensors in real time mode when sensor signals, and other chemistry and operational data, are collected and continuously analysed with data acquisition and evaluation software. Technical knowledge was acquired in water chemistry control techniques (grab sampling, on-line monitoring, data collecting and processing, etc), plant chemistry and corrosion diagnostics, plant monitoring (corrosion, chemistry, activity) and plant chemistry improvement (analytical models and practices). This publication covers contributions from leading experts in water chemistry/corrosion, representing organizations from 16 countries with the largest nuclear capacities

  11. Fungal disease detection in plants: Traditional assays, novel diagnostic techniques and biosensors.

    Science.gov (United States)

    Ray, Monalisa; Ray, Asit; Dash, Swagatika; Mishra, Abtar; Achary, K Gopinath; Nayak, Sanghamitra; Singh, Shikha

    2017-01-15

    Fungal diseases in commercially important plants results in a significant reduction in both quality and yield, often leading to the loss of an entire plant. In order to minimize the losses, it is essential to detect and identify the pathogens at an early stage. Early detection and accurate identification of pathogens can control the spread of infection. The present article provides a comprehensive overview of conventional methods, current trends and advances in fungal pathogen detection with an emphasis on biosensors. Traditional techniques are the "gold standard" in fungal detection which relies on symptoms, culture-based, morphological observation and biochemical identifications. In recent times, with the advancement of biotechnology, molecular and immunological approaches have revolutionized fungal disease detection. But the drawback lies in the fact that these methods require specific and expensive equipments. Thus, there is an urgent need for rapid, reliable, sensitive, cost effective and easy to use diagnostic methods for fungal pathogen detection. Biosensors would become a promising and attractive alternative, but they still have to be subjected to some modifications, improvements and proper validation for on-field use. Copyright © 2016 Elsevier B.V. All rights reserved.

  12. Molecular Diagnostics for the Study of Hypersonic Flows

    Science.gov (United States)

    2000-04-01

    UNCLASSIFIED Defense Technical Information Center Compilation Part Notice ADPO10744 TITLE: Molecular Diagnostics for the Study of Hypersonic Flows...following component part numbers comprise the compilation report: ADP010736 thru ADPO10751 UNCLASSIFIED 5-1 Molecular Diagnostics for the Study of

  13. Automatic vibration monitoring system for the diagnostic inspection of the WWER-440 type nuclear power plants

    International Nuclear Information System (INIS)

    Hollo, E.; Siklossy, P.; Toth, Zs.

    1982-01-01

    In the Hungarian Research Institute for Electric Power Industry (VEIKI) an automatic vibration monitoring system for diagnostics and inspection of nuclear power plants of type WWER-440 was developed. The paper summarizes the results of this work and investigates the use of mechanical vibrations and oscillations induced by flow for fault diagnosis. The design of the hardware system, the present software possibilities, the laboratory experiments and the guidelines for future software developments are also described in detail. (A.L.)

  14. Prodiag--a hybrid artificial intelligence based reactor diagnostic system for process faults

    International Nuclear Information System (INIS)

    Reifman, J.; Wei, T.Y.C.; Vitela, J.E.; Applequist, C. A.; Chasensky, T.M.

    1996-01-01

    Commonwealth Research Corporation (CRC) and Argonne National Laboratory (ANL) are collaborating on a DOE-sponsored Cooperative Research and Development Agreement (CRADA), project to perform feasibility studies on a novel approach to Artificial Intelligence (Al) based diagnostics for component faults in nuclear power plants. Investigations are being performed in the construction of a first-principles physics-based plant level process diagnostic expert system (ES) and the identification of component-level fault patterns through operating component characteristics using artificial neural networks (ANNs). The purpose of the proof-of-concept project is to develop a computer-based system using this Al approach to assist process plant operators during off-normal plant conditions. The proposed computer-based system will use thermal hydraulic (T-H) signals complemented by other non-T-H signals available in the data stream to provide the process operator with the component which most likely caused the observed process disturbance.To demonstrate the scale-up feasibility of the proposed diagnostic system it is being developed for use with the Chemical Volume Control System (CVCS) of a nuclear power plant. A full-scope operator training simulator representing the Commonwealth Edison Braidwood nuclear power plant is being used both as the source of development data and as the means to evaluate the advantages of the proposed diagnostic system. This is an ongoing multi-year project and this paper presents the results to date of the CRADA phase

  15. Development and testing of a diagnostic system for intelligen distributed control at EBR-2

    International Nuclear Information System (INIS)

    Edwards, R.M.; Ruhl, D.W.; Klevans, E.H.; Robinson, G.E.

    1990-01-01

    A diagnostic system is under development for demonstration of Intelligent Distributed Control at the Experimental Breeder Reactor (EBR--II). In the first phase of the project a diagnostic system is being developed for the EBR-II steam plant based on the DISYS expert systems approach. Current testing uses recorded plant data and data from simulated plant faults. The dynamical simulation of the EBR-II steam plant uses the Babcock and Wilcox (B ampersand W) Modular Modeling System (MMS). At EBR-II the diagnostic system operates in the UNIX workstation and receives live plant data from the plant Data Acquisition System (DAS). Future work will seek implementation of the steam plant diagnostic in a distributed manner using UNIX based computers and Bailey microprocessor-based control system. 10 refs., 6 figs

  16. Development of a high cycle vibration fatigue diagnostic system with non-contact vibration sensing

    International Nuclear Information System (INIS)

    Doi, So-myo; Nekomoto, Yoshitsugu; Takeishi, Masayuki; Miyoshi, Toshiaki; O'shima, Eiji

    1999-01-01

    In nuclear power plants, it is very important to foresee occurring events with in-operation -inspection (IOI) since the foreseeing makes plant maintenance more speedy and reliable. Moreover, information on plant condition under operating would make period of in-service inspection (ISI) shorter because maintenance plan can be made effectively using the information. In this study, a high cycle fatigue diagnostic system is being developed applying to especially pipe branches with small diameter under in-operating condition, which are in the radioactive areas of PWR plants and hard to access. This paper presents a concept of the in-operating diagnostic system and current status of developing sensing systems. (author)

  17. Some aspects of diagnostic systems perspective

    International Nuclear Information System (INIS)

    Korosec, D.

    1998-01-01

    The integrity and safety of all nuclear power plant systems and components is guaranteed by the high requirements to quality assurance during all phases of design, fabrication, construction and operation. Many of the countries operating nuclear facilities, introduced advanced, sophisticated diagnostic systems for continuous monitoring safety important process parameters. The licensee should perform an assessment of the existing diagnostic systems, often supplied by the original design, their reliability and the need for the introduction of the additional monitoring/diagnostic systems. The operating experience should be taken into account and the assessment of the further needs. On this field has to be made on the results of PSA studies. In addition to the cost benefit analysis the evaluation of the new diagnostic systems in the light of nuclear safety should be also made. Experience, gained from the utilities, which have already installed this kind of the equipment should be very useful. Introducing new diagnostic systems will require often a safety assessment of the necessary modifications. Licensing process should be based on the existing nuclear legislation with certain additional requirements. (author)

  18. Development and improvement of the operating diagnostics systems of NPO CKTI works for turbine of thermal and nuclear power plants

    Science.gov (United States)

    Kovalev, I. A.; Rakovskii, V. G.; Isakov, N. Yu.; Sandovskii, A. V.

    2016-03-01

    The work results on the development and improvement of the techniques, algorithms, and software-hardware of continuous operating diagnostics systems of rotating units and parts of turbine equipment state are presented. In particular, to ensure the full remote service of monitored turbine equipment using web technologies, the web version of the software of the automated systems of vibration-based diagnostics (ASVD VIDAS) was developed. The experience in the automated analysis of data obtained by ASVD VIDAS form the basis of the new algorithm of early detection of such dangerous defects as rotor deflection, crack in the rotor, and strong misalignment of supports. The program-technical complex of monitoring and measuring the deflection of medium pressure rotor (PTC) realizing this algorithm will alert the electric power plant staff during a deflection and indicate its value. This will give the opportunity to take timely measures to prevent the further extension of the defect. Repeatedly, recorded cases of full or partial destruction of shrouded shelves of rotor blades of the last stages of low-pressure cylinders of steam turbines defined the need to develop a version of the automated system of blade diagnostics (ASBD SKALA) for shrouded stages. The processing, analysis, presentation, and backup of data characterizing the mechanical state of blade device are carried out with a newly developed controller of the diagnostics system. As a result of the implementation of the works, the diagnosed parameters determining the operation security of rotating elements of equipment was expanded and the new tasks on monitoring the state of units and parts of turbines were solved. All algorithmic solutions and hardware-software implementations mentioned in the article were tested on the test benches and applied at some power plants.

  19. Tokamak physics experiment: Diagnostic windows study

    International Nuclear Information System (INIS)

    Merrigan, M.; Wurden, G.A.

    1995-11-01

    We detail the study of diagnostic windows and window thermal stress remediation in the long-pulse, high-power Tokamak Physics Experiment (TPX) operation. The operating environment of the TPX diagnostic windows is reviewed, thermal loads on the windows estimated, and cooling requirements for the windows considered. Applicable window-cooling technology from other fields is reviewed and its application to the TPX windows considered. Methods for TPX window thermal conditioning are recommended, with some discussion of potential implementation problems provided. Recommendations for further research and development work to ensure performance of windows in the TPX system are presented

  20. PC based diagnostic system for nitrogen production unit of HWP

    International Nuclear Information System (INIS)

    Lamba, D.S.; Rao, V.C.; Krishnan, S.; Kamaraj, T.; Krishnaswamy, C.

    1992-01-01

    The plant diagnostic system monitors the input data from local processing unit and tries to diagnose the cause of the failure. The system is a rule based application program that can perform tasks itself using fault tree model which displays the logical relationships between critical events and their possible ways occurrence, i.e. hardware failure, process faults and human error etc. Unit 37 Nitrogen Plant is taken as a prototype model for trying the plant diagnostics system. (author). 3 refs., 2 figs

  1. The wireless diagnostic system for motor operated valves

    International Nuclear Information System (INIS)

    Ito, Haruo; Akiyama, Michiaki; Suzuki, Syunichi

    2010-01-01

    To aim at maintenance optimization, a motor operated valve (MOV) diagnostic system called 'MOVDAS' has been developed by using new sensor technologies incorporating torque sensor into the MOV. It has been introduced into nuclear power plants operated by Japan Atomic Power Company (JAPC) for the support of Condition Based Maintenance (CBM). This system, directly checking the torque behavior of the MOV, accurately diagnoses the condition of the MOV during plant operation. Further for the ease of data collection and manpower saving, the wireless diagnostic system based on MOVDAS utilizing Personal Handyphone System (PHS) has been recently introduced into nuclear power plants in JAPC. (author)

  2. Operational experiences on the Borssele nuclear power plant using computer based surveillance and diagnostic system on-line

    International Nuclear Information System (INIS)

    Turkcan, E.; Quaadvliet, W.H.J.; Peeters, T.T.J.M.; Verhoef, J.P

    1991-06-01

    The on-line monitoring and diagnostics system of Borssele nuclear power plant (NPP), designed and established by the ECN Energy Research Foundation, has been operating continuously since 1983. The system is extended in form of multiprocessing, multi-tasking structure performing real-time monitoring, on-line reactor parameters' calculation, data-base preparation for expert systems and providing early information on possible malfunctions even in the incipient stage making alert by passive alarms. The system realized has already been operating in the course of 7 fuel cycles of the reactor starting from start-up through normal power operation. An expert system operating on the VAX work station is added to the surveillance and diagnostics system for data base management of the observed physical parameters relevant to the NPP under supervision. The paper highlights the surveillance and diagnostic modules involved, in their actual hierarchical form in use, presents theoretical considerations applied to the design of the surveillance system together with the results obtained through the 12th to 17th fuel cycles of the NPP including start-ups and shut-downs and reveals the experience thus gained by both utility and ECN through the application of the system described. (author). 19 refs.; 4 figs

  3. Efficient strategies to find diagnostic test accuracy studies in kidney journals.

    Science.gov (United States)

    Rogerson, Thomas E; Ladhani, Maleeka; Mitchell, Ruth; Craig, Jonathan C; Webster, Angela C

    2015-08-01

    Nephrologists looking for quick answers to diagnostic clinical questions in MEDLINE can use a range of published search strategies or Clinical Query limits to improve the precision of their searches. We aimed to evaluate existing search strategies for finding diagnostic test accuracy studies in nephrology journals. We assessed the accuracy of 14 search strategies for retrieving diagnostic test accuracy studies from three nephrology journals indexed in MEDLINE. Two investigators hand searched the same journals to create a reference set of diagnostic test accuracy studies to compare search strategy results against. We identified 103 diagnostic test accuracy studies, accounting for 2.1% of all studies published. The most specific search strategy was the Narrow Clinical Queries limit (sensitivity: 0.20, 95% CI 0.13-0.29; specificity: 0.99, 95% CI 0.99-0.99). Using the Narrow Clinical Queries limit, a searcher would need to screen three (95% CI 2-6) articles to find one diagnostic study. The most sensitive search strategy was van der Weijden 1999 Extended (sensitivity: 0.95; 95% CI 0.89-0.98; specificity 0.55, 95% CI 0.53-0.56) but required a searcher to screen 24 (95% CI 23-26) articles to find one diagnostic study. Bachmann 2002 was the best balanced search strategy, which was sensitive (0.88, 95% CI 0.81-0.94), but also specific (0.74, 95% CI 0.73-0.75), with a number needed to screen of 15 (95% CI 14-17). Diagnostic studies are infrequently published in nephrology journals. The addition of a strategy for diagnostic studies to a subject search strategy in MEDLINE may reduce the records needed to screen while preserving adequate search sensitivity for routine clinical use. © 2015 Asian Pacific Society of Nephrology.

  4. Systems for noise diagnostics of WWER nuclear power plants

    International Nuclear Information System (INIS)

    Por, G.

    1996-01-01

    The aim of this paper is to give a short overview of the noise diagnostics system developed by Hungarian firms which are in operation in WWER type NPP Units. Giving a list of systems developed for noise diagnostics of WWER reactors we present their main characteristics, their goal and some of their achievements. The second part deals with the problem of acceptance of noise system by NPP and regulations. (author). 24 refs

  5. Systems for noise diagnostics of WWER nuclear power plants

    Energy Technology Data Exchange (ETDEWEB)

    Por, G [Technical Univ. of Budapest, Budapest (Hungary)

    1997-12-31

    The aim of this paper is to give a short overview of the noise diagnostics system developed by Hungarian firms which are in operation in WWER type NPP Units. Giving a list of systems developed for noise diagnostics of WWER reactors we present their main characteristics, their goal and some of their achievements. The second part deals with the problem of acceptance of noise system by NPP and regulations. (author). 24 refs.

  6. Assessing variability in results in systematic reviews of diagnostic studies

    NARCIS (Netherlands)

    Naaktgeboren, Christiana A; Ochodo, Eleanor A; Van Enst, Wynanda A; de Groot, Joris A H; Hooft, Lotty; Leeflang, Mariska M G; Bossuyt, Patrick M; Moons, Karel G M; Reitsma, Johannes B

    2016-01-01

    BACKGROUND: To describe approaches used in systematic reviews of diagnostic test accuracy studies for assessing variability in estimates of accuracy between studies and to provide guidance in this area. METHODS: Meta-analyses of diagnostic test accuracy studies published between May and September

  7. Detailed pharmacognostical studies on Berberis aristata DC plant

    Directory of Open Access Journals (Sweden)

    Bhawana Rathi

    2013-01-01

    Full Text Available Background: Berberis aristata DC (Berberidaceae commonly known in Hindi as "Dāruhaldi" and "Citra," is an important medicinal herb native to Northern Himalaya region. The plant is used traditionally in Indian system of medicine as an antibacterial, antiperiodic, antidiarrheal and anticancer and it is also used in the treatment of ophthalmic infections. Its root, stem and leaves also find their use in treatment of various ailments and hence is used extensively in Ayurveda. Materials and Methods: Samples of the whole plants of B. aristata were collected and identified. Hand and microtome sections were taken, stained and mounted and the cell content and cell wall structure were studied according to the method described by Kay and Johansen. Representative sketches were made with the help of camera Lucida. Methods for determining the quantitative values were the same as described elsewhere. For fluorescence analysis, the powder of the root, stem and leaf were examined under ultraviolet light. Total ash, acid insoluble ash and water-soluble ash values and water- and alcohol-soluble extractives were determined. Results: The detailed investigations carried on the pharmacognosy of the root; stem and leaf of B. aristata have brought out some salient diagnostic features, which allow one to differentiate it from other substitutes and or adulterants. The determination of quantitative values, fluorescence analysis and the use of lycopodium spore analysis has specifically contributed to this differentiation. Conclusion: From the foregoing observation on the pharmacognosy of root, stem and leaf of B. aristata DC, the salient diagnostic characters of three parts have been presented, which can allow one to differentiate it from other substitutes and or adulterants.

  8. The diagnostic and therapeutic impact of MRI: an observational multi-centre study

    International Nuclear Information System (INIS)

    Hollingworth, William; Todd, Christopher J.; Bell, Matthew I.; Arafat, Qais; Girling, Simon; Karia, Kanti R.; Dixon, Adrian K.

    2000-01-01

    AIM: To provide information about the diagnostic and therapeutic impact of magnetic resonance imaging (MRI) and to compare the findings across diagnostic groups. MATERIALS AND METHODS: A prospective, observational study of 2017 consecutive referrals for MRI of the head, spine or knee at four imaging centres. Clinicians completed questionnaires before MRI stating initial diagnoses, diagnostic confidence and treatment plans. After imaging, a second questionnaire evaluated clinicians' revised diagnosis and treatment plans in the light of imaging findings. Patients were grouped into nine diagnostic categories for analysis. Comparison between pre- and post-imaging was used to assess the diagnostic and therapeutic impact of MRI. RESULTS: In seven of nine diagnostic groups MRI findings were associated with a diagnostic impact. Diagnoses were revised or discarded following normal MR findings and diagnostic confidence was increased by confirmative MR findings. There was no statistically significant diagnostic impact for suspected pituitary or cerebello-pontine angle lesions. In five of nine diagnostic groups (knee meniscus, knee ligament, multiple sclerosis, lumbar and cervical spine) MRI findings had a clear impact on treatment plans. CONCLUSION: This study demonstrates that in most diagnostic categories, MRI influences diagnosis and treatment. However, experimental studies are needed to prove that these diagnostic and therapeutic impacts lead to improved health. Hollingworth (2000)

  9. The diagnostic and therapeutic impact of MRI: an observational multi-centre study

    Energy Technology Data Exchange (ETDEWEB)

    Hollingworth, William; Todd, Christopher J.; Bell, Matthew I.; Arafat, Qais; Girling, Simon; Karia, Kanti R.; Dixon, Adrian K

    2000-11-01

    AIM: To provide information about the diagnostic and therapeutic impact of magnetic resonance imaging (MRI) and to compare the findings across diagnostic groups. MATERIALS AND METHODS: A prospective, observational study of 2017 consecutive referrals for MRI of the head, spine or knee at four imaging centres. Clinicians completed questionnaires before MRI stating initial diagnoses, diagnostic confidence and treatment plans. After imaging, a second questionnaire evaluated clinicians' revised diagnosis and treatment plans in the light of imaging findings. Patients were grouped into nine diagnostic categories for analysis. Comparison between pre- and post-imaging was used to assess the diagnostic and therapeutic impact of MRI. RESULTS: In seven of nine diagnostic groups MRI findings were associated with a diagnostic impact. Diagnoses were revised or discarded following normal MR findings and diagnostic confidence was increased by confirmative MR findings. There was no statistically significant diagnostic impact for suspected pituitary or cerebello-pontine angle lesions. In five of nine diagnostic groups (knee meniscus, knee ligament, multiple sclerosis, lumbar and cervical spine) MRI findings had a clear impact on treatment plans. CONCLUSION: This study demonstrates that in most diagnostic categories, MRI influences diagnosis and treatment. However, experimental studies are needed to prove that these diagnostic and therapeutic impacts lead to improved health. Hollingworth (2000)

  10. Low activation diagnostic equipment design studies

    International Nuclear Information System (INIS)

    Hopkins, G.R.; Cheng, E.T.; Fisher, R.K.

    1985-01-01

    The low activation fusion concept has been applied to the diagnostic equipment in a fusion reactor. The components where fabrication from low activation materials is feasible have been identified. Other systems where higher activation elements are required can have their activation reduced by design approaches which include shielding and operation only in low flux regions of the reactor. Some components will not operate in a high flux so activation is not a major concern. This low activation diagnostic equipment study completes a series of low activation studies where all the components in a fusion power reactor have now been evaluated. It is concluded that a completely low activation fusion reactor is feasible with all components meeting the functional requirements. This provides an environmentally benign energy source with a high confidence level in meeting safety criteria in operation, maintenance and waste disposal

  11. Main feedwater valve diagnostics at Waterford 3 nuclear generating station

    International Nuclear Information System (INIS)

    Fitzgerald, W.V.

    1991-01-01

    Pneumatically-operated control valves are coming under increasing scrutiny in nuclear power plants because of their relatively high incident rate. The theory behind a device that could make performance evaluation of these valves simpler and more effective was first described at the original EPRI Power Plant Valve Symposium. The development of this Diagnostic System was completed in 1989, and it was recently used to troubleshoot two main feedwater valves at Louisiana Power and Light's Waterford 3 Power Station. During a cold snap last December, these valves failed to respond to the input signal and, as a result, the plant came off line. An incident report had to be filed, and the plant chose to contact the original equipment manufacturer (OEM) for assistance. This paper describes the original incident involving these valves and then gives a brief description of the diagnostic system and how it works. The balance of the paper then reviews how the OEM and plant personnel utilized the system to evaluate each component of the control valve assembly (I/P transducer, positioner, volume boosters, actuator, and valve body assembly). By simply stroking the valve and monitoring pneumatic signals and valve position, the problem was traced to a malfunctioning positioner and a volume booster that was leaking. The problems were corrected and new performance signatures run for the valves using the system to document their improved operation. This case study demonstrates how new Diagnostic Technology along with OEM involvement can effectively address problems with pneumatically-operated control valves so that root-cause solutions can be implemented

  12. Data driven approaches for diagnostics and optimization of NPP operation

    International Nuclear Information System (INIS)

    Pliska, J.; Machat, Z.

    2014-01-01

    The efficiency and heat rate is an important indicator of both the health of the power plant equipment and the quality of power plant operation. To achieve this challenges powerful tool is a statistical data processing of large data sets which are stored in data historians. These large data sets contain useful information about process quality and equipment and sensor health. The paper discusses data-driven approaches for model building of main power plant equipment such as condenser, cooling tower and the overall thermal cycle as well using multivariate regression techniques based on so called a regression triplet - data, model and method. Regression models comprise a base for diagnostics and optimization tasks. Diagnostics and optimization tasks are demonstrated on practical cases - diagnostics of main power plant equipment to early identify equipment fault, and optimization task of cooling circuit by cooling water flow control to achieve for a given boundary conditions the highest power output. (authors)

  13. Field-based systems and advanced diagnostics

    International Nuclear Information System (INIS)

    Eryurek, E.

    1998-01-01

    Detection and characterization of anomalies in an industrial plant provide improved plant availability and plant efficiency thus yielding increased economic efficiency. Traditionally, detection of process anomalies is done at a high-level control system through various signal validation methods. These signal validation techniques rely on data from transmitters, which measure related process variables. Correlating these signals and deducing anomalies often is a very time consuming and a difficult task. Delays in detecting these anomalies can be costly during plant operation. Conventional centralized approaches also suffer from their dependence on detailed mathematical models of the processes. Smart field devices have the advantage of providing the necessary information directly to the control system as anomalies develop during operation of the processes enabling operators to take necessary steps to either prevent an unnecessary shut down before the problem becomes serious or schedule maintenance on the problematic loop. Fisher-Rosemount's PlantWeb TM architecture addresses 'Enhanced Measurement, Advanced Diagnostics and Control in the Field'. PlantWeb TM builds open process management systems by networking intelligent field devices, scalable control and systems platforms, and integrated modular software. A description of PlantWeb TM and how it improves various process conditions and reduces operating cost of a plant as well as a high level description of 'Enhanced Measurement, Advanced Diagnostics and Control in the Field', will be provided in this paper. PlantWeb TM is the trademark for Fisher-Rosemount's new field-based architecture that uses emerging technologies to utilize the power of intelligent field devices and deliver critical process and equipment information to improve plant performance. (author)

  14. BWR recirculation pump diagnostic expert system

    International Nuclear Information System (INIS)

    Chiang, S.C.; Morimoto, C.N.; Torres, M.R.

    2004-01-01

    At General Electric (GE), an on-line expert system to support maintenance decisions for BWR recirculation pumps for nuclear power plants has been developed. This diagnostic expert system is an interactive on-line system that furnishes diagnostic information concerning BWR recirculation pump operational problems. It effectively provides the recirculation pump diagnostic expertise in the plant control room continuously 24 hours a day. The expert system is interfaced to an on-line monitoring system, which uses existing plant sensors to acquire non-safety related data in real time. The expert system correlates and evaluates process data and vibration data by applying expert rules to determine the condition of a BWR recirculation pump system by applying knowledge based rules. Any diagnosis will be automatically displayed, indicating which pump may have a problem, the category of the problem, and the degree of concern expressed by the validity index and color hierarchy. The rules incorporate the expert knowledge from various technical sources such as plant experience, engineering principles, and published reports. These rules are installed in IF-THEN formats and the resulting truth values are also expressed in fuzzy terms and a certainty factor called a validity index. This GE Recirculation Pump Expert System uses industry-standard software, hardware, and network access to provide flexible interfaces with other possible data acquisition systems. Gensym G2 Real-Time Expert System is used for the expert shell and provides the graphical user interface, knowledge base, and inference engine capabilities. (author)

  15. In-service diagnostics of pumping facilities

    International Nuclear Information System (INIS)

    Jaros, I.

    1987-01-01

    The potential is discussed of technical diagnostics in increasing operating reliability of pumping facilities of conventional and nuclear power plants, and in rationalizing the system of their maintenance. Attention is focused on the selection of diagnostic parameters in which the so-called subjective expert methodology is applied, and on the diagnostic system design. At this stage, the construction of the respective facility and the analysis of the failure rate of its individual assemblies should be considered. The selection of diagnostic means directly depends on the selection of diagnostic parameters and is conditional on other factors, such as availability, cost, technical service, and operator's training. Briefly characterized are Czechoslovak standards assessing the mechanical condition of rotary machines from the measurement of the effective value of the rate of their oscillations. (Z.M.)

  16. Diagnostic reasoning strategies and diagnostic success.

    Science.gov (United States)

    Coderre, S; Mandin, H; Harasym, P H; Fick, G H

    2003-08-01

    Cognitive psychology research supports the notion that experts use mental frameworks or "schemes", both to organize knowledge in memory and to solve clinical problems. The central purpose of this study was to determine the relationship between problem-solving strategies and the likelihood of diagnostic success. Think-aloud protocols were collected to determine the diagnostic reasoning used by experts and non-experts when attempting to diagnose clinical presentations in gastroenterology. Using logistic regression analysis, the study found that there is a relationship between diagnostic reasoning strategy and the likelihood of diagnostic success. Compared to hypothetico-deductive reasoning, the odds of diagnostic success were significantly greater when subjects used the diagnostic strategies of pattern recognition and scheme-inductive reasoning. Two other factors emerged as independent determinants of diagnostic success: expertise and clinical presentation. Not surprisingly, experts outperformed novices, while the content area of the clinical cases in each of the four clinical presentations demonstrated varying degrees of difficulty and thus diagnostic success. These findings have significant implications for medical educators. It supports the introduction of "schemes" as a means of enhancing memory organization and improving diagnostic success.

  17. Nuclear power plant diagnostics - Safety aspects and licensing. Report of a technical committee meeting. Working material

    International Nuclear Information System (INIS)

    1997-01-01

    The aim of the Technical Committee Meeting (TCM) was to review developed systems and methods in diagnostics in the scope of their impacts and importance to the safety of Nuclear Power Plants. Papers presented on TCM came from different sources, from developers, from manufacturers, from licensing authorities and from NPP personal. They reflect up to date status in the given subject. Participants of TCM formulated three working groups to elaborate different questions which were raised during the discussions. Their results are reflected in the three chapter titles of the given material. Annex 1 to this document contains presentations made at the Technical Committee Meeting. Refs, figs, tabs

  18. Diagnostic time in digital pathology: A comparative study on 400 cases

    Directory of Open Access Journals (Sweden)

    Aleksandar Vodovnik

    2016-01-01

    Full Text Available Background: Numerous validation studies in digital pathology confirmed its value as a diagnostic tool. However, a longer time to diagnosis than traditional microscopy has been seen as a significant barrier to the routine use of digital pathology. As a part of our validation study, we compared a digital and microscopic diagnostic time in the routine diagnostic setting. Materials and Methods: One senior staff pathologist reported 400 consecutive cases in histology, nongynecological, and fine needle aspiration cytology (20 sessions, 20 cases/session, over 4 weeks. Complex, difficult, and rare cases were excluded from the study to reduce the bias. A primary diagnosis was digital, followed by traditional microscopy, 6 months later, with only request forms available for both. Microscopic slides were scanned at ×20, digital images accessed through the fully integrated laboratory information management system (LIMS and viewed in the image viewer on double 23” displays. A median broadband speed was 299 Mbps. A diagnostic time was measured from the point slides were made available to the point diagnosis was made or additional investigations were deemed necessary, recorded independently in minutes/session and compared. Results: A digital diagnostic time was 1841 and microscopic 1956 min; digital being shorter than microscopic in 13 sessions. Four sessions with shorter microscopic diagnostic time included more cases requiring extensive use of magnifications over ×20. Diagnostic time was similar in three sessions. Conclusions: A diagnostic time in digital pathology can be shorter than traditional microscopy in the routine diagnostic setting, with adequate and stable network speeds, fully integrated LIMS and double displays as default parameters. This also related to better ergonomics, larger viewing field, and absence of physical slide handling, with effects on both diagnostic and nondiagnostic time. Differences with previous studies included a design

  19. A plant control system development approach for IRIS

    International Nuclear Information System (INIS)

    Wood, R.T.; Brittain, C.R.; March-Leuba, J.A.; Conway, L.E.; Oriani, L.

    2003-01-01

    The plant control system concept for the International Reactor Innovative and Secure (IRIS) will make use of integrated control, diagnostic, and decision modules to provide a highly automated intelligent control capability. The plant control system development approach established for IRIS involves determination and verification of control strategies based on whole-plant simulation; identification of measurement, control, and diagnostic needs; development of an architectural framework in which to integrate an intelligent plant control system; and design of the necessary control and diagnostic elements for implementation and validation. This paper describes key elements of the plant control system development approach established for IRIS and presents some of the strategies and methods investigated to support the desired control capabilities. (author)

  20. An Advanced Diagnostic Display for Core Protection Calculator System

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Ji-Hyeon; Jeong, See-Chae; Sohn, Se-Do [Korea Power Engineering Company, Daejeon (Korea, Republic of)

    2008-10-15

    The main purpose of a Nuclear Power Plant Instrumentation and Control (I and C) Display System is to provide operator's interface for I and C systems. The CPCS display(Shin-Kori 1 and 2) provides operators with 1) plant monitoring values of field input and algorithm variables that reflect the reactor core conditions, 2) operation values that operators can change and 3) CPCS status. It will be an optimal case if operators can understand the plant (including CPCS itself) condition intuitively with the displayed values but it is not easy in CPCS. For example, if the CPCS Channel Trouble light is lit, operators need some amount of time to investigate what caused the trouble light because there are more than hundred causes that can generate the channel trouble. If a Display supports diagnostic information that shows what cause the displayed alarms, it will greatly help operators in easy understanding the CPCS status. To provide these diagnostic information, this paper suggests an active self-explanatory display mechanism. This self-explanatory diagnostic display mechanism utilizes an ontology in XML that describes parent child, sibling relationships of display variables, through which in-depth, in-breadth diagnostic tracking is possible. This paper consists of two parts. First, the key features of CPCS Flat Panel Display System (FPDS) are described. Second, the features of active self explanatory diagnostic display are discussed.

  1. An Advanced Diagnostic Display for Core Protection Calculator System

    International Nuclear Information System (INIS)

    Kim, Ji-Hyeon; Jeong, See-Chae; Sohn, Se-Do

    2008-01-01

    The main purpose of a Nuclear Power Plant Instrumentation and Control (I and C) Display System is to provide operator's interface for I and C systems. The CPCS display(Shin-Kori 1 and 2) provides operators with 1) plant monitoring values of field input and algorithm variables that reflect the reactor core conditions, 2) operation values that operators can change and 3) CPCS status. It will be an optimal case if operators can understand the plant (including CPCS itself) condition intuitively with the displayed values but it is not easy in CPCS. For example, if the CPCS Channel Trouble light is lit, operators need some amount of time to investigate what caused the trouble light because there are more than hundred causes that can generate the channel trouble. If a Display supports diagnostic information that shows what cause the displayed alarms, it will greatly help operators in easy understanding the CPCS status. To provide these diagnostic information, this paper suggests an active self-explanatory display mechanism. This self-explanatory diagnostic display mechanism utilizes an ontology in XML that describes parent child, sibling relationships of display variables, through which in-depth, in-breadth diagnostic tracking is possible. This paper consists of two parts. First, the key features of CPCS Flat Panel Display System (FPDS) are described. Second, the features of active self explanatory diagnostic display are discussed

  2. Results of an integration study of a diagnostics port plug in ITER

    International Nuclear Information System (INIS)

    Salasca, Sophie; Cantone, Bruno; Grosman, André; Esposito, Basilio; Moro, Fabio; Morocco, Daniele; Villari, Rosaria; Angelone, Maurizio; Rincon, Esther; Hidalgo, Carlos; Nagy, Daniel; Kocsis, Gabor; Varela, Paulo; Porempovics, Gabor; Perrollaz, Guillaume; Patel, Kunal; Krivchenkov, Yuri; Walsh, Michael

    2013-01-01

    Highlights: ► An extensive study on the integration of diagnostics in a port plug of ITER has been performed. ► It has shown that the diagnostic performances could not be reached if their number was not decreased. ► A design of Diagnostic Shield Modules has been validated through mechanical and thermal analyses. ► These analyses have confirmed that the highest loads are concentrated in the vicinity of the plasma. -- Abstract: Diagnostics in ITER are mandatory to characterize the parameters of plasma and study its interactions with plasma-facing components. Diagnostics components in the vicinity of the plasma are supported by metallic structures called port plugs. At the tokamak mid-plane, these components are installed in port plugs through intermediate structures called drawers. Apart from hosting the diagnostics, the port plugs act as shielding against neutrons and gammas, in order to limit the nuclear loads in crucial components (such as diagnostics and superconducting coils) as well as the dose levels in the controlled zones of the tokamak. The radiation shielding function of the port plugs is ensured through an optimized mixture of heavy metallic materials and water, forming shielding blocks surrounding the diagnostics and called Diagnostic Shield Modules (DSMs). These DSMs constitute the rear part of the drawers (the front part being composed of the Diagnostic First Wall). This paper presents the main results of a study performed in Europe on the integration of a particular diagnostics port plug, the Equatorial Port Plug 1 (EPP1). The paper first provides the results of the EPP1 diagnostics integration analysis. In a second step it focuses on the design of the EPP1 DSMs and summarizes the major results of a thorough set of analyses aiming at studying the DSMs behaviour under different loads, suggesting recommendations to improve their current design

  3. Thermal diagnostics in power plant to improve performance

    International Nuclear Information System (INIS)

    Meister, H.

    1995-01-01

    The improvement of older power plants by changing poor performing components is a cost effective method to increase the capacity of the units. The necessary information for the detection of components that are to be replaced can be obtained from heat rate and component tests with accuracy instrumentation. The discussed methods and tools provided by ABB Were used with success in several power plants in Europe. These tools are in the process of permanent improvement and can be used in almost any type of power plant. Due to the reasons discussed above, there is a high potential for improvement of a lot of power plants in the next decade. (author)

  4. Diagnostic accuracy of organ electrodermal diagnostics | Szopinski ...

    African Journals Online (AJOL)

    Objective. To estimate the diagnostic accuracy as well as the scope of utilisation of a new bio-electronic method of organ diagnostics. Design. Double-blind comparative study of the diagnostic results obtained by means of organ electrodermal diagnostics (OED) and clinical diagnoses, as a criterion standard. Setting.

  5. Cooperative research and development for artificial intelligence based reactor diagnostic system

    International Nuclear Information System (INIS)

    Reifman, J.; Wei, T.Y.C.; Abboud, R.G.; Chasensky, T.M.

    1994-01-01

    Artificial Intelligence (AI) techniques in the form of knowledge-based Expert Systems (ESs) have been proposed to provide on-line decision-making support for plant operators during both normal and emergency conditions. However, in spite of the great interest in these advanced techniques, their application in the diagnosis of large-scale processes has not yet reached its full potential because of limitations of the knowledge base. These limitations include problems with knowledge acquisition and the use of an event-oriented approach for process diagnosis. To investigate the capabilities of this two-level hierarchical knowledge structure, Commonwealth Research Corporation (CRC) and Argonne National Laboratory (ANL)are collaborating on a DOE-sponsored Cooperative Research and Development Agreement (CRADA) project to perform feasibility studies on the proposed diagnostic system. Investigations are being performed in the construction of a physics-based plant level process diagnostic ES and the characterization of component-level fault project is to develop a computer-based system using this Al approach to assist process plant operators during off-normal plant conditions. The proposed computer-based system will use T-H signals complemented by other non-T-H signals available in the data stream to provide the process operator with the component which most likely caused the observed process disturbance. To demonstrate the scale-up feasibility of the proposed diagnostic system it is being developed for use with the Chemical Volume Control System (CVCS) of a nuclear power plant. This is an ongoing multi-year project and the remainder of this paper presents a mid-term status report

  6. Development of advanced diagnostic technologies for motor-operated valves

    International Nuclear Information System (INIS)

    Hegi, Kotaro; Shimizu, Shunichi; Higuma, Koji; Nishino, Koji; Osaki, Kenji; Watanabe, Kazumi; Hamano, Frank

    2010-01-01

    As use of condition-based maintenance is allowed in the new regulatory inspection system employed in Japan's nuclear power plants in 2009, development of advanced diagnostic technologies for motor-operated valves (MOVs) is now required. This report discusses advanced technologies in valve-setup verification, valve performance evaluation, monitoring of valve/actuator conditions by performance diagnostic system and moreover detection of stem crack by ultrasonic diagnostic system. (author)

  7. Multi-method automated diagnostics of rotating machines

    Science.gov (United States)

    Kostyukov, A. V.; Boychenko, S. N.; Shchelkanov, A. V.; Burda, E. A.

    2017-08-01

    The automated machinery diagnostics and monitoring systems utilized within the petrochemical plants are an integral part of the measures taken to ensure safety and, as a consequence, the efficiency of these industrial facilities. Such systems are often limited in their functionality due to the specifics of the diagnostic techniques adopted. As the diagnostic techniques applied in each system are limited, and machinery defects can have different physical nature, it becomes necessary to combine several diagnostics and monitoring systems to control various machinery components. Such an approach is inconvenient, since it requires additional measures to bring the diagnostic results in a single view of the technical condition of production assets. In this case, we mean by a production facility a bonded complex of a process unit, a drive, a power source and lines. A failure of any of these components will cause an outage of the production asset, which is unacceptable. The purpose of the study is to test a combined use of vibration diagnostics and partial discharge techniques within the diagnostic systems of enterprises for automated control of the technical condition of rotating machinery during maintenance and at production facilities. The described solutions allow you to control the condition of mechanical and electrical components of rotating machines. It is shown that the functionality of the diagnostics systems can be expanded with minimal changes in technological chains of repair and operation of rotating machinery. Automation of such systems reduces the influence of the human factor on the quality of repair and diagnostics of the machinery.

  8. EnergiTools(R) - a power plant performance monitoring and diagnosis tool

    International Nuclear Information System (INIS)

    Ancion, P.V.; Bastien, R.; Ringdahl, K.

    2000-01-01

    Westinghouse EnergiTools(R) is a performance diagnostic tool for power generation plants that combines the power of on-line process data acquisition with advanced diagnostics methodologies. The system uses analytical models based on thermodynamic principles combined with knowledge of component diagnostic experts. An issue in modeling expert knowledge is to have a framework that can represent and process uncertainty in complex systems. In such experiments, it is nearly impossible to build deterministic models for the effects of faults on symptoms. A methodology based on causal probabilistic graphs, more specifically on Bayesian belief networks, has been implemented in EnergiTools(R) to capture the fault-symptom relationships. The methodology estimates the likelihood of the various component failures using the fault-symptom relationships. The system also has the ability to use neural networks for processes that are difficult to model analytically. An application is the estimation of the reactor power in nuclear power plant by interpreting several plant indicators. EnergiTools(R) is used for the on-line performance monitoring and diagnostics at Vattenfall Ringhals nuclear power plants in Sweden. It has led to the diagnosis of various performance issues with plant components. Two case studies are presented. In the first case, an overestimate of the thermal power due to a faulty instrument was found, which led to a plant operation below its optimal power. The paper shows how the problem was discovered, using the analytical thermodynamic calculations. The second case shows an application of EnergiTools(R) for the diagnostic of a condenser failure using causal probabilistic graphs

  9. Expert system applications in support of system diagnostics and prognostics at EBR-II

    International Nuclear Information System (INIS)

    Lehto, W.K.; Gross, K.C.

    1989-01-01

    Expert systems have been developed to aid in the monitoring and diagnostics of the Experimental Breeder Reactor-II (EBR-II) at the Idaho National Engineering Laboratory (INEL) in Idaho Falls, Idaho. Systems have been developed for failed fuel surveillance and diagnostics and reactor coolant pump monitoring and diagnostics. A third project is being done jointly by ANL-W and EG ampersand G Idaho to develop a transient analysis system to enhance overall plant diagnostic and prognostic capability. The failed fuel surveillance and diagnosis system monitors, processes, and interprets information from nine key plant sensors. It displays to the reactor operator diagnostic information needed to make proper decisions regarding technical specification conformance during reactor operation with failed fuel. 8 refs., 9 figs., 2 tabs

  10. 76 FR 54193 - Fiscal Year 2012 Veterinary Import/Export, Diagnostic Services, and Export Certification for...

    Science.gov (United States)

    2011-08-31

    ...] Fiscal Year 2012 Veterinary Import/Export, Diagnostic Services, and Export Certification for Plants and.... SUMMARY: This notice pertains to user fees charged for Veterinary Services animal quarantine and other..., organisms, and vectors; for certain veterinary diagnostic services; and for export certification of plants...

  11. Studies on the diagnostic accuracy of lymphography

    International Nuclear Information System (INIS)

    Luening, M.; Stargardt, A.; Abet, L.

    1979-01-01

    Contradictory reports in the literature on the reliability of lymphography stimulated the authors to test the diagnostic accuracy, employing methods which are approximately analogous to practice, using carcinoma of the cervix as the model on which the study was carried out. Using 21 observers it was found that there was no correlation between their experience and on-target accuracy of the diagnosis. Good observers obtained an accuracy of 85% with good proportions between sensitivity in the recognition of detail, specificity and readiness to arrive at a decision on the basis of discriminatory ability. With the help of the concept of the ROC curves, the position taken up by the observers in respect of diagnostic decisions, and a complex manner of assessing the various characteristic factors determining diagnostic accuracy, are demonstrated. This form of test, which permits manipulation of different variants of diagnosis, is recommended, among other things, for performance control at the end of training and continuing education courses in other fields of x-ray diagnosis as well. (orig.) [de

  12. Diagnostic orientation in control of disturbance situations

    International Nuclear Information System (INIS)

    Hukki, K.; Norros, L.

    1993-01-01

    The object of the study is diagnostic judgement in the control of dynamic processes. The starting point was the known difficulty process operators have in utilizing knowledge of process dynamics in disturbance situations that require both diagnostic and prognostic actions. A model of the diagnostic judgement process as a construction of coherent interpretation of the situation is outlined, and comprehensive data from simulated disturbance handling by 6 crews of a PWR type nuclear power plant was analysed. The phase of analysis included evaluation of the adequacy of task performance, utilization of available process information, and evaluation of the interpretation of disturbance situations. The results suggest that a functional orientation towards task performance allows a more coherent and comprehensive interpretation of the situation and more adequate task performance. Coherence of interpretation seems to be reflected in a higher subjective certainty compared with crews with an incoherent interpretation. (author). 15 refs, 2 figs, 2 tabs

  13. Summary of EPRI projects for improving power plant maintenance and maintainability

    International Nuclear Information System (INIS)

    Shugars, H.G.; Poole, D.N.; Pack, R.W.

    1979-01-01

    The Electric Power Research Institute is sponsoring projects to improve power plant maintenance and maintainability. Areas presently being emphasized are improvements in plant design for maintainability, improvements in performing nuclear plant refuelings, and development of on-line monitoring and diagnostic systems for various plant components. The seven projects are reviewed. They are: (1) human factors review of power plant maintainability; (2) refueling outage improvement; (3) on-line monitoring and diagnostics for power plant machinery; (4) acoustic emission and vibrati1on signature analysis of fossil fuel plant components; (5) acoustic monitoring of power plant valves; (6) on-line monitoring and diagnostics for generators; and (7) detection of water induction in steam turbines. Each project contractor and the project manager are listed for reference. 8 references

  14. Development of plant maintenance systems

    International Nuclear Information System (INIS)

    Tomita, Jinji; Ike, Masae; Nakayama, Kenji; Kato, Hisatomo

    1989-01-01

    Toshiba is making active efforts for the continuing improvement of reliability and maintainability of operating nuclear power plants. As a part of these efforts, the company has developed new maintenance administration systems, diagnostic monitoring facilities for plant equipments, computer-aided expert systems, and remote-controlled machines for maintenance work. The maintenance administration systems provide efficient work plans and data acquisition capabilities for the management of personnel and equipments involved in nuclear power plant maintenance. The plant diagnostic facilities monitor and diagnose plant conditions for preventive maintenance, as well as enabling rapid countermeasures to be carried out should they be required. Expert systems utilizing artificial intelligence (AI) technology are also employed. The newly developed remote-controlled machines are useful tools for the maintenance inspection of equipment which can not be easily accessed. (author)

  15. Role of theoretical dynamics in vibration diagnostics of pipe systems

    International Nuclear Information System (INIS)

    Rejent, B.

    1992-01-01

    The importance of vibration diagnostics of pipe systems and the relevance of theoretical dynamics are shown using examples. The problems are discussed of vibration diagnostics of the primary circuit of a nuclear power plant with viscous seismic dampers installed. (M.D.) 7 figs., 5 refs

  16. Three principles to define the success of a diagnostic study could be identified

    DEFF Research Database (Denmark)

    Vach, Werner; Gerke, Oke; Høilund-Carlsen, Poul Flemming

    2012-01-01

    of a diagnostic study on a single binary test and investigation of common statistical approaches in relation to these criteria. RESULTS: Three criteria for defining the overall success of a diagnostic study could be identified: a strong criterion, a liberal criterion, and a weak criterion. The strong criterion...... can be implemented by comparing the lower bounds of the confidence intervals for sensitivity and specificity with prespecified target values, as is typically done in many diagnostic studies. The liberal criterion allows a clinically meaningful compensation between sensitivity and specificity and can...... be implemented in different ways. If the liberal criterion is applied instead of the strong criterion, this can lead to a substantial reduction in the sample size required for a diagnostic study. The weak criterion is not very adequate for defining the success of a diagnostic study. CONCLUSION: When planning...

  17. Relating faults in diagnostic reasoning with diagnostic errors and patient harm.

    NARCIS (Netherlands)

    Zwaan, L.; Thijs, A.; Wagner, C.; Wal, G. van der; Timmermans, D.R.M.

    2012-01-01

    Purpose: The relationship between faults in diagnostic reasoning, diagnostic errors, and patient harm has hardly been studied. This study examined suboptimal cognitive acts (SCAs; i.e., faults in diagnostic reasoning), related them to the occurrence of diagnostic errors and patient harm, and studied

  18. Methodological quality of diagnostic accuracy studies on non-invasive coronary CT angiography: influence of QUADAS (Quality Assessment of Diagnostic Accuracy Studies included in systematic reviews) items on sensitivity and specificity

    International Nuclear Information System (INIS)

    Schueler, Sabine; Walther, Stefan; Schuetz, Georg M.; Schlattmann, Peter; Dewey, Marc

    2013-01-01

    To evaluate the methodological quality of diagnostic accuracy studies on coronary computed tomography (CT) angiography using the QUADAS (Quality Assessment of Diagnostic Accuracy Studies included in systematic reviews) tool. Each QUADAS item was individually defined to adapt it to the special requirements of studies on coronary CT angiography. Two independent investigators analysed 118 studies using 12 QUADAS items. Meta-regression and pooled analyses were performed to identify possible effects of methodological quality items on estimates of diagnostic accuracy. The overall methodological quality of coronary CT studies was merely moderate. They fulfilled a median of 7.5 out of 12 items. Only 9 of the 118 studies fulfilled more than 75 % of possible QUADAS items. One QUADAS item (''Uninterpretable Results'') showed a significant influence (P = 0.02) on estimates of diagnostic accuracy with ''no fulfilment'' increasing specificity from 86 to 90 %. Furthermore, pooled analysis revealed that each QUADAS item that is not fulfilled has the potential to change estimates of diagnostic accuracy. The methodological quality of studies investigating the diagnostic accuracy of non-invasive coronary CT is only moderate and was found to affect the sensitivity and specificity. An improvement is highly desirable because good methodology is crucial for adequately assessing imaging technologies. (orig.)

  19. Methodological quality of diagnostic accuracy studies on non-invasive coronary CT angiography: influence of QUADAS (Quality Assessment of Diagnostic Accuracy Studies included in systematic reviews) items on sensitivity and specificity

    Energy Technology Data Exchange (ETDEWEB)

    Schueler, Sabine; Walther, Stefan; Schuetz, Georg M. [Humboldt-Universitaet zu Berlin, Freie Universitaet Berlin, Charite Medical School, Department of Radiology, Berlin (Germany); Schlattmann, Peter [University Hospital of Friedrich Schiller University Jena, Department of Medical Statistics, Informatics, and Documentation, Jena (Germany); Dewey, Marc [Humboldt-Universitaet zu Berlin, Freie Universitaet Berlin, Charite Medical School, Department of Radiology, Berlin (Germany); Charite, Institut fuer Radiologie, Berlin (Germany)

    2013-06-15

    To evaluate the methodological quality of diagnostic accuracy studies on coronary computed tomography (CT) angiography using the QUADAS (Quality Assessment of Diagnostic Accuracy Studies included in systematic reviews) tool. Each QUADAS item was individually defined to adapt it to the special requirements of studies on coronary CT angiography. Two independent investigators analysed 118 studies using 12 QUADAS items. Meta-regression and pooled analyses were performed to identify possible effects of methodological quality items on estimates of diagnostic accuracy. The overall methodological quality of coronary CT studies was merely moderate. They fulfilled a median of 7.5 out of 12 items. Only 9 of the 118 studies fulfilled more than 75 % of possible QUADAS items. One QUADAS item (''Uninterpretable Results'') showed a significant influence (P = 0.02) on estimates of diagnostic accuracy with ''no fulfilment'' increasing specificity from 86 to 90 %. Furthermore, pooled analysis revealed that each QUADAS item that is not fulfilled has the potential to change estimates of diagnostic accuracy. The methodological quality of studies investigating the diagnostic accuracy of non-invasive coronary CT is only moderate and was found to affect the sensitivity and specificity. An improvement is highly desirable because good methodology is crucial for adequately assessing imaging technologies. (orig.)

  20. An integrated real-time diagnostic concept using expert systems, qualitative reasoning and quantitative analysis

    International Nuclear Information System (INIS)

    Edwards, R.M.; Lee, K.Y.; Kumara, S.; Levine, S.H.

    1989-01-01

    An approach for an integrated real-time diagnostic system is being developed for inclusion as an integral part of a power plant automatic control system. In order to participate in control decisions and automatic closed loop operation, the diagnostic system must operate in real-time. Thus far, an expert system with real-time capabilities has been developed and installed on a subsystem at the Experimental Breeder Reactor (EBR-II) in Idaho, USA. Real-time simulation testing of advanced power plant concepts at the Pennsylvania State University has been developed and was used to support the expert system development and installation at EBR-II. Recently, the US National Science Foundation (NSF) and the US Department of Energy (DOE) have funded a Penn State research program to further enhance application of real-time diagnostic systems by pursuing implementation in a distributed power plant computer system including microprocessor based controllers. This paper summarizes past, current, planned, and possible future approaches to power plant diagnostic systems research at Penn State. 34 refs., 9 figs

  1. The Limpopo Non-Metropolitan Drinking Water Supplier Response to a Diagnostic Tool for Technical Compliance.

    Science.gov (United States)

    Nefale, Avhashoni D; Kamika, Ilunga; Obi, Chikwelu L; Momba, Maggy Nb

    2017-07-19

    Water services providers should supply water that is fit for human consumption, taking into account multi-barrier approaches and technical aspects such as design aspects, operation monitoring, final water quality compliance monitoring, plant monitoring practices, maintenance, and risk management practices. Against this background, this study focused on applying the diagnostic tool for technical compliance as well as assessing the compliance of water treatment plants with management norms. Six plants in the Vhembe District Municipality were selected; the Vondo, Malamulele, Mutshedzi, and Mutale plants (conventional), and the Dzingahe and Tshedza package plants. During the first assessment, four (Malamulele, Mutshedzi, Mutale and Dzingahe) plants scored between 44% and 49% and achieved Class 3 certification, revealing serious challenges requiring immediate intervention. Two water plants (Vondo and Tshedza, scoring 53% and 63%, respectively) were in the Class 2 category, revealing serious challenges requiring attention and improvement. During the second assessment, all plants scored between 63% and 87% (Class 2 category). The greatest improvement (30%) was noted for the Dzingahe and Tshedza plants, followed by the Malamulele plant, while the Mutale, Vondo, and Mutshedzi plants improved their scores by 20%, 17% and 14%, respectively. After corrective actions and re-measurement, no plant complied. It is recommended that Water Services Providers (WSPs) regularly apply the diagnostic tools and water safety plans as developed in order to comply with applicable standards.

  2. The Limpopo Non-Metropolitan Drinking Water Supplier Response to a Diagnostic Tool for Technical Compliance

    Directory of Open Access Journals (Sweden)

    Avhashoni D. Nefale

    2017-07-01

    Full Text Available Water services providers should supply water that is fit for human consumption, taking into account multi-barrier approaches and technical aspects such as design aspects, operation monitoring, final water quality compliance monitoring, plant monitoring practices, maintenance, and risk management practices. Against this background, this study focused on applying the diagnostic tool for technical compliance as well as assessing the compliance of water treatment plants with management norms. Six plants in the Vhembe District Municipality were selected; the Vondo, Malamulele, Mutshedzi, and Mutale plants (conventional, and the Dzingahe and Tshedza package plants. During the first assessment, four (Malamulele, Mutshedzi, Mutale and Dzingahe plants scored between 44% and 49% and achieved Class 3 certification, revealing serious challenges requiring immediate intervention. Two water plants (Vondo and Tshedza, scoring 53% and 63%, respectively were in the Class 2 category, revealing serious challenges requiring attention and improvement. During the second assessment, all plants scored between 63% and 87% (Class 2 category. The greatest improvement (30% was noted for the Dzingahe and Tshedza plants, followed by the Malamulele plant, while the Mutale, Vondo, and Mutshedzi plants improved their scores by 20%, 17% and 14%, respectively. After corrective actions and re-measurement, no plant complied. It is recommended that Water Services Providers (WSPs regularly apply the diagnostic tools and water safety plans as developed in order to comply with applicable standards.

  3. Automatic acoustic and vibration monitoring system for nuclear power plants

    International Nuclear Information System (INIS)

    Tothmatyas, Istvan; Illenyi, Andras; Kiss, Jozsef; Komaromi, Tibor; Nagy, Istvan; Olchvary, Geza

    1990-01-01

    A diagnostic system for nuclear power plant monitoring is described. Acoustic and vibration diagnostics can be applied to monitor various reactor components and auxiliary equipment including primary circuit machinery, leak detection, integrity of reactor vessel, loose parts monitoring. A noise diagnostic system has been developed for the Paks Nuclear Power Plant, to supervise the vibration state of primary circuit machinery. An automatic data acquisition and processing system is described for digitalizing and analysing diagnostic signals. (R.P.) 3 figs

  4. On-line diagnostic techniques for air-operated control valves based on time series analysis

    International Nuclear Information System (INIS)

    Ito, Kenji; Matsuoka, Yoshinori; Minamikawa, Shigeru; Komatsu, Yasuki; Satoh, Takeshi.

    1996-01-01

    The objective of this research is to study the feasibility of applying on-line diagnostic techniques based on time series analysis to air-operated control valves - numerous valves of the type which are used in PWR plants. Generally the techniques can detect anomalies by failures in the initial stages for which detection is difficult by conventional surveillance of process parameters measured directly. However, the effectiveness of these techniques depends on the system being diagnosed. The difficulties in applying diagnostic techniques to air-operated control valves seem to come from the reduced sensitivity of their response as compared with hydraulic control systems, as well as the need to identify anomalies in low level signals that fluctuate only slightly but continuously. In this research, simulation tests were performed by setting various kinds of failure modes for a test valve with the same specifications as of a valve actually used in the plants. Actual control signals recorded from an operating plant were then used as input signals for simulation. The results of the tests confirmed the feasibility of applying on-line diagnostic techniques based on time series analysis to air-operated control valves. (author)

  5. A diagnostic expert system for a boiling water reactor using a dynamic model

    International Nuclear Information System (INIS)

    Sonoda, Y.; Kanemoto, S.; Imaruoka, H.

    1990-01-01

    A diagnostic expert system for abnormal disturbances in a BWR (Boiling Water Reactor) plant has been developed. The peculiar feature of this system is a diagnostic method which combines artificial intelligence technique with numerical analysis technique. The system has three diagnostic functions, 1) identification of anomaly position (device or sensor), 2) identification of anomaly mode and 3) identification of anomaly cause. Function 1) is implemented as follows. First, a hypothesis about anomaly propagation paths is built up by qualitative reasoning, using knowledge of causal relations among observed signals. Next, the abnormal device or sensor is found by applying model reference method and fuzzy set theory to test the hypothesis, using knowledge of plant structure and function, heuristic strategy of diagnosis and module type dynamic simulator. This simulator is composed of basic transfer function modules. The simulation model for the testing region is built up automatically, according to the requirement from the diagnostic task. Function 2) means identification of dynamic characteristics for an anomaly. It is realized by tuning model parameters so as to reproduce the abnormal signal behavior using the non-linear programing method. Function 3) derives probable anomaly causes from heuristic rules between anomaly mode and cause. A basic plant dynamic model was built up and adjusted to dynamic characteristics for one BWR plant (1100MWe). In order to verify the diagnostic functions of this system, data for several abnormal events was compiled by modifying this model. The diagnostic functions were proved useful, through the simulated abnormal data

  6. Plant life management study of Japanese nuclear power plants

    International Nuclear Information System (INIS)

    Fukuda, Toshihiko

    1999-01-01

    Already more than twenty-five years have passed since the first commercial LWR plant went into operation in Japan. In this situation, MITI and 3 electric utilities (Tokyo Electric Power Company, Kansai Electric Power Co., Inc, Japan Atomic Power Company) have started a plant life management (PLM) study from 1994 to evaluate the long-term integrity of major systems, structures and components of aged LWR plants and ensure the safe, steady and highly reliable long-term operation. It consists of two phases: part 1 study and part 2 study. The part 1 study started in 1994 and focused on seven typical safety-related components. The part 1 study reports were made public in 1996. The part 2 study started in 1997. In this study we reviewed not only safety-related components but also plant reliability related components. The part 2 study reports were opened to the public in February 1999. This paper shows a summary of the part 2 study and our future PLM program. (author)

  7. Determination of diagnostic standards on saturated soil extracts for cut roses grown in greenhouses.

    Science.gov (United States)

    Franco-Hermida, John Jairo; Quintero, María Fernanda; Cabrera, Raúl Iskander; Guzman, José Miguel

    2017-01-01

    This work comprises the theoretical determination and validation of diagnostic standards for the analysis of saturated soil extracts for cut rose flower crops (Rosa spp.) growing in the Bogota Plateau, Colombia. The data included 684 plant tissue analyses and 684 corresponding analyses of saturated soil extracts, all collected between January 2009 and June 2013. The tissue and soil samples were selected from 13 rose farms, and from cultivars grafted on the 'Natal Briar' rootstock. These concurrent samples of soil and plant tissues represented 251 production units (locations) of approximately 10,000 m2 distributed across the study area. The standards were conceived as a tool to improve the nutritional balance in the leaf tissue of rose plants and thereby define the norms for expressing optimum productive potential relative to nutritional conditions in the soil. To this end, previously determined diagnostic standard for rose leaf tissues were employed to obtain rates of foliar nutritional balance at each analyzed location and as criteria for determining the diagnostic norms for saturated soil extracts. Implementing this methodology to foliar analysis, showed a higher significant correlation for diagnostic indices. A similar behavior was observed in saturated soil extracts analysis, becoming a powerful tool for integrated nutritional diagnosis. Leaf analyses determine the most limiting nutrients for high yield and analyses of saturated soil extracts facilitate the possibility of correcting the fertigation formulations applied to soils or substrates. Recommendations are proposed to improve the balance in soil-plant system with which the possibility of yield increase becomes more probable. The main recommendations to increase and improve rose crop flower yields would be: continuously check pH values of SSE, reduce the amounts of P, Fe, Zn and Cu in fertigation solutions and carefully analyze the situation of Mn in the soil-plant system.

  8. Uprading of existing treatment plants in Poland

    OpenAIRE

    Stene-Johansen, S.; Paulsrud, B.

    1994-01-01

    During the first Phase, diagnostic studies have been carried out at selected treatment plants in order to identify problems and how to improve treatment efficiency (Report 1 st. Phase). The report in hand (2nd. Phase) gives recommendations for upgrading/rehabilitation and other improvements based on full scale experiments at selected treatment plants. State Pollution Control Authority (SFT) The Royal Norwegian Ministry of Environment (MD)

  9. Check valve diagnostics utilizing acoustic and magnetic technologies

    International Nuclear Information System (INIS)

    Agostinelli, A.

    1991-01-01

    The potential hazards associated with check valve failures make it necessary to detect check valve problems before they cause significant damage. In the nuclear industry, check valve failures are known to have resulted in damaging water hammer conditions, overpressurization of low pressure systems, steam binding of auxiliary feedwater pumps, and other serious component damage in power plant environments. Similar problems exist in fossil power and various process industries, but the resources dedicated to valve maintenance issues are greatly reduced. However, the trend toward plant life extension, predictive maintenance, and maximum operating efficiency will raise the general awareness of check valve maintenance in commercial (non-nuclear) applications. Although this paper includes specific references to the nuclear industry, the check valve problem conditions and diagnostic techniques apply across all power and process plant environments. The ability to accurately diagnose check valve conditions using non-intrusive, predictive maintenance testing methods allows for a more cost-efficient, productive maintenance program. One particular diagnostic system, called Quickcheck trademark, assists utilities in addressing these concerns. This article presents actual field test data and analysis that demonstrate the power of check valve diagnostics. Prior to presenting the field data, a brief overview of the system is overviewed

  10. Data handling at EBR-II [Experimental Breeder Reactor II] for advanced diagnostics and control work

    International Nuclear Information System (INIS)

    Lindsay, R.W.; Schorzman, L.W.

    1988-01-01

    Improved control and diagnostics systems are being developed for nuclear and other applications. The Experimental Breeder Reactor II (EBR-II) Division of Argonne National Laboratory has embarked on a project to upgrade the EBR-II control and data handling systems. The nature of the work at EBR-II requires that reactor plant data be readily available for experimenters, and that the plant control systems be flexible to accommodate testing and development needs. In addition, operational concerns require that improved operator interfaces and computerized diagnostics be included in the reactor plant control system. The EBR-II systems have been upgraded to incorporate new data handling computers, new digital plant process controllers, and new displays and diagnostics are being developed and tested for permanent use. In addition, improved engineering surveillance will be possible with the new systems

  11. Research at ITER towards DEMO: Specific reactor diagnostic studies to be carried out on ITER

    Energy Technology Data Exchange (ETDEWEB)

    Krasilnikov, A. V.; Kaschuck, Y. A.; Vershkov, V. A.; Petrov, A. A.; Petrov, V. G.; Tugarinov, S. N. [Institution Project center ITER, Moscow (Russian Federation)

    2014-08-21

    In ITER diagnostics will operate in the very hard radiation environment of fusion reactor. Extensive technology studies are carried out during development of the ITER diagnostics and procedures of their calibration and remote handling. Results of these studies and practical application of the developed diagnostics on ITER will provide the direct input to DEMO diagnostic development. The list of DEMO measurement requirements and diagnostics will be determined during ITER experiments on the bases of ITER plasma physics results and success of particular diagnostic application in reactor-like ITER plasma. Majority of ITER diagnostic already passed the conceptual design phase and represent the state of the art in fusion plasma diagnostic development. The number of related to DEMO results of ITER diagnostic studies such as design and prototype manufacture of: neutron and γ–ray diagnostics, neutral particle analyzers, optical spectroscopy including first mirror protection and cleaning technics, reflectometry, refractometry, tritium retention measurements etc. are discussed.

  12. Research at ITER towards DEMO: Specific reactor diagnostic studies to be carried out on ITER

    Science.gov (United States)

    Krasilnikov, A. V.; Kaschuck, Y. A.; Vershkov, V. A.; Petrov, A. A.; Petrov, V. G.; Tugarinov, S. N.

    2014-08-01

    In ITER diagnostics will operate in the very hard radiation environment of fusion reactor. Extensive technology studies are carried out during development of the ITER diagnostics and procedures of their calibration and remote handling. Results of these studies and practical application of the developed diagnostics on ITER will provide the direct input to DEMO diagnostic development. The list of DEMO measurement requirements and diagnostics will be determined during ITER experiments on the bases of ITER plasma physics results and success of particular diagnostic application in reactor-like ITER plasma. Majority of ITER diagnostic already passed the conceptual design phase and represent the state of the art in fusion plasma diagnostic development. The number of related to DEMO results of ITER diagnostic studies such as design and prototype manufacture of: neutron and γ-ray diagnostics, neutral particle analyzers, optical spectroscopy including first mirror protection and cleaning technics, reflectometry, refractometry, tritium retention measurements etc. are discussed.

  13. Research at ITER towards DEMO: Specific reactor diagnostic studies to be carried out on ITER

    International Nuclear Information System (INIS)

    Krasilnikov, A. V.; Kaschuck, Y. A.; Vershkov, V. A.; Petrov, A. A.; Petrov, V. G.; Tugarinov, S. N.

    2014-01-01

    In ITER diagnostics will operate in the very hard radiation environment of fusion reactor. Extensive technology studies are carried out during development of the ITER diagnostics and procedures of their calibration and remote handling. Results of these studies and practical application of the developed diagnostics on ITER will provide the direct input to DEMO diagnostic development. The list of DEMO measurement requirements and diagnostics will be determined during ITER experiments on the bases of ITER plasma physics results and success of particular diagnostic application in reactor-like ITER plasma. Majority of ITER diagnostic already passed the conceptual design phase and represent the state of the art in fusion plasma diagnostic development. The number of related to DEMO results of ITER diagnostic studies such as design and prototype manufacture of: neutron and γ–ray diagnostics, neutral particle analyzers, optical spectroscopy including first mirror protection and cleaning technics, reflectometry, refractometry, tritium retention measurements etc. are discussed

  14. Do invasive alien plants really threaten river bank vegetation? A case study based on plant communities typical for Chenopodium ficifolium—An indicator of large river valleys

    Science.gov (United States)

    Nowak, Arkadiusz; Rola, Kaja

    2018-01-01

    Riparian zones are very rich in species but subjected to strong anthropogenic changes and extremely prone to alien plant invasions, which are considered to be a serious threat to biodiversity. Our aim was to determine the spatial distribution of Chenopodium ficifolium, a species demonstrating strong confinement to large river valleys in Central Europe and an indicator of annual pioneer nitrophilous vegetation developing on river banks, which are considered to be of importance to the European Community. Additionally, the habitat preferences of the species were analysed. Differences in the richness and abundance of species diagnostic for riverside habitats, as well as the contribution of resident and invasive alien species in vegetation plots along three rivers differing in terms of size and anthropogenic impact were also examined. Finally, the effect of invaders on the phytocoenoses typical for C. ficifolium was assessed. The frequency of C. ficifolium clearly decreased with an increasing distance from the river. Among natural habitats, the species mostly preferred the banks of large rivers. The vegetation plots developing on the banks of the three studied rivers differed in total species richness, the number and cover of resident, diagnostic and invasive alien species, as well as in species composition. Our research indicates that abiotic and anthropogenic factors are the most significant drivers of species richness and plant cover of riverbank vegetation, and invasive alien plants affect this type of vegetation to a small extent. PMID:29543919

  15. Do invasive alien plants really threaten river bank vegetation? A case study based on plant communities typical for Chenopodium ficifolium-An indicator of large river valleys.

    Science.gov (United States)

    Nobis, Agnieszka; Nowak, Arkadiusz; Rola, Kaja

    2018-01-01

    Riparian zones are very rich in species but subjected to strong anthropogenic changes and extremely prone to alien plant invasions, which are considered to be a serious threat to biodiversity. Our aim was to determine the spatial distribution of Chenopodium ficifolium, a species demonstrating strong confinement to large river valleys in Central Europe and an indicator of annual pioneer nitrophilous vegetation developing on river banks, which are considered to be of importance to the European Community. Additionally, the habitat preferences of the species were analysed. Differences in the richness and abundance of species diagnostic for riverside habitats, as well as the contribution of resident and invasive alien species in vegetation plots along three rivers differing in terms of size and anthropogenic impact were also examined. Finally, the effect of invaders on the phytocoenoses typical for C. ficifolium was assessed. The frequency of C. ficifolium clearly decreased with an increasing distance from the river. Among natural habitats, the species mostly preferred the banks of large rivers. The vegetation plots developing on the banks of the three studied rivers differed in total species richness, the number and cover of resident, diagnostic and invasive alien species, as well as in species composition. Our research indicates that abiotic and anthropogenic factors are the most significant drivers of species richness and plant cover of riverbank vegetation, and invasive alien plants affect this type of vegetation to a small extent.

  16. A Study on a Hybrid Approach for Diagnosing Faults in Nuclear Power Plant

    International Nuclear Information System (INIS)

    Yang, M.; Zhang, Z.J.; Peng, M.J.; Yan, S.Y.; Wang, H.; Ouyang, J.

    2006-01-01

    Proper and rapid identification of malfunctions is of premier importance for the safe operation of Nuclear Power Plants (NPP). Many monitoring or/and diagnosis methodologies based on artificial and computational intelligence have been proposed to aid operator to understand system problems, perform trouble-shooting action and reduce human error under serious pressure. However, because no single method is adequate to handle all requirements for diagnostic system, hybrid approaches where different methods work in conjunction to solve parts of the problem interest researchers greatly. In this study, Multilevel Flow Models (MFM) and Artificial Neural Network (ANN) are proposed and employed to develop a fault diagnosis system with the intention of improving the success rate of recognition on the one hand, and improving the understandability of diagnostic process and results on the other hand. Several simulation cases were conducted for evaluating the performance of the proposed diagnosis system. The simulation results validated the effectiveness of the proposed hybrid approach. (authors)

  17. Development of process diagnostic techniques for piping and equipment

    International Nuclear Information System (INIS)

    Yotsutsuji, Mitoshi

    1987-01-01

    The thing required for using the facilities composing a plant for a long period without anxiety is to quantitatively grasp the quantities of the present condition of the facilities and to take the necessary measures beforehand. For this purpose, the diagnostic techniques for quickly and accurately detect the quantities of the condition of facilities are necessary, and the development of process diagnostic techniques has been desired. The process diagnostic techniques mentioned here mean those for diagnosing the contamination, clogging and performance of towers, tanks, heat exchangers and others. Idemitsu Engineering Co. had developed a simplified diagnostic equipment for detecting the state of fouling in piping in 1982, which is the gamma ray transmission diagnosis named Scale Checker. By further improving it, the process diagnostic techniques for piping and equipment were developed. In this report, the course of development and examination, the principle of detection, the constitution and the examination of remodeling of the Scale Checker are reported. As the cases of process diagnosis in plant facilities, the diagnosis of the clogging in process piping and the diagnosis of the performance of a distillation tower were carried out. The contents of the diagnosis and the results of those cases are explained. (Kako, I.)

  18. 9 CFR 147.8 - Procedures for preparing egg yolk samples for diagnostic tests.

    Science.gov (United States)

    2010-01-01

    ... samples for diagnostic tests. 147.8 Section 147.8 Animals and Animal Products ANIMAL AND PLANT HEALTH... IMPROVEMENT PLAN Blood Testing Procedures § 147.8 Procedures for preparing egg yolk samples for diagnostic... for diagnostic testing. (b) The authorized laboratory must identify each egg as to the breeding flock...

  19. Malaria Laboratory Diagnostic Performance: Case studies of two ...

    African Journals Online (AJOL)

    Advantages of rapid diagnostic tests when compared with microscopy are simple to perform, fast, low ... The study was conducted to establish the performance of laboratory diagnosis of malaria in local Malawi .... Government of Malawi.

  20. Experimental design: Case studies of diagnostics optimization for W7-X

    International Nuclear Information System (INIS)

    Dreier, H.; Dinklage, A.; Fischer, R.; Hartfuss, H.-J.; Hirsch, M.; Kornejew, P.; Pasch, E.; Turkin, Yu.

    2005-01-01

    The preparation of diagnostics for Wendelstein 7-X is accompanied by diagnostics simulations and optimization. Starting from the physical objectives, the design of diagnostics should incorporate predictive modelling (e.g. transport modelling) and simulations of respective measurements. Although technical constraints are governing design considerations, it appears that several design parameters of different diagnostics can be optimized. However, a general formulation for fusion diagnostics design in terms of optimization is lacking. In this paper, first case studies of Bayesian experimental design aiming at applications on W7-X diagnostics preparation are presented. The information gain of a measurement is formulated as a utility function which is expressed in terms of the Kullback-Leibler divergence. Then, the expected range of data is to be included and the resulting expected utility represents the objective for optimization. Bayesian probability theory gives a framework allowing us for an appropriate formulation of the design problem in terms of probability distribution functions. Results are obtained for the information gain from interferometry and for the design of polychromators for Thomson scattering. For interferometry, studies of the choice of line-of-sights for optimum signal and for the reproduction of gradient positions are presented for circular, elliptical and W7-X geometries. For Thomson scattering, the design of filter transmissions for density and temperature measurements are discussed. (author)

  1. Noise diagnostics research at the Institute for Electric Power Research

    International Nuclear Information System (INIS)

    Voeroess, L.

    1983-01-01

    The main goal of recent research is the designing of a diagnostic system for the Paks nuclear power plant. It includes the designing of measuring cascades for measuring mechanical vibrations caused by flow and pressure fluctuations in the primary coolant circuit, the arrangement of measuring cascades for measuring turbine bearing vibrations in the secondary coolant circuit, and the development, manufacturing and commissioning of a central data acquisition and processing unit for the whole diagnostic system. Simultaneously computer models are developed for improving the interpretation. Moreover, it is planned to develop methods for estimating residual lifetime and the status of plant components. (author)

  2. Preliminary Study of Late Pleistocene to Early Holocene Plant Food Strategies in China

    Science.gov (United States)

    Hayashi Tang, M.; Liu, X.; Fritz, G.; Zhao, Z.

    2017-12-01

    In recent decades, studies on the domestication and early cultivation of seed crops have contributed significantly to how we understand human-plant interactions, and their impact on human social organisation and the environment. It is becoming clear, however, that plants have been critical to the human diet for much longer and in more diverse ways than previously assumed. This paper is a preliminary attempt at identifying and addressing early prehistoric plant food strategies in China. In particular, very little is known about the use of vegetatively propagated plants, despite their significant representation in modern crops. Many ingredients of Chinese medicine are also roots and tubers (or vegetative storage organs, VSOs). Unlike seed crops, however, we lack a systematic criterion for examining diagnostic characters of different VSO taxa in the archaeological record. To address this issue, we characterized commonly consumed and historically significant VSOs in China, by studying experimentally charred modern samples under the optical microscope and scanning electron microscope. We then compared the characteristics of these modern VSO samples against plant remains from Late Pleistocene to early Holocene archaeological sites in China, such as Zengpiyan (Guangxi), Zhaoguodong (Guizhou), and Jiahu (Henan) sites. We found that different taxa of VSOs can be differentiated by using multiple lines of evidence, including: shape and size of various cells, texture and arrangement of cell walls, as well as anatomical arrangements of organs, especially the vascular bundles. Though identification can be difficult when fragile cell structures have collapsed or deteriorated, more robust features are often preserved for diagnosis. Our results suggest that the potential for studying the role of vegetatively propagated plants in early human-environmental interactions is overlooked, and can be expanded significantly with further investment in their systematic identification.

  3. Quality of dementia diagnostic evaluation for ethnic minority patients: a nationwide study

    DEFF Research Database (Denmark)

    Nielsen, T Rune; Andersen, Birgitte Bo; Kastrup, Marianne

    2011-01-01

    Background/Aims: Diagnostic evaluation of dementia for ethnic minority patients may be challenging. This study aimed to evaluate the quality of diagnostic evaluation of dementia for patients from ethnic minorities in Denmark. Methods: The Danish national hospital registers were used to identify p......: There are significant ethnic disparities in the quality of diagnostic evaluations and outcome of dementia in the secondary healthcare sector....

  4. In-service diagnostic systems of steam generators, pressurizers and other components of WWER type nuclear power plants

    International Nuclear Information System (INIS)

    Matal, O.

    1988-01-01

    A detailed description is presented of the systems of vibration inspections and systems of determining residual service life, implemented as in-service diagnostic systems for steam generators and pressurizers at the Dukovany nuclear power plant. Low temperature accelerometers of the KD or KS type and high temperature accelerometers CA 91 are used as vibration sensors. In the system of vibration inspection a total of 64 vibration measuring chains of Czechoslovak make and design are installed in the power plant. Systems are being built for determining residual service life which consist of 75 special chains for heat monitoring with thermocouples installed on selected assemblies of the steam generators and the pressurizers serving to monitor and evaluate heat stress. Also included in the system for determining residual service life are 16 routes for water withdrawal from steam generators. Their purpose is to make in-service determinations of places of biggest concentrations of impurities in secondary water, to determine the biggest local chemical exposure of primary collector and heat exchange tube materials and to optimize the size and place of leachate withdrawal. (Z.M.). 2 figs., 2 tabs., 15 refs

  5. Advanced diagnostic graphics

    International Nuclear Information System (INIS)

    Bray, M.A.; Petersen, R.J.; Clark, M.T.; Gertman, D.I.

    1981-01-01

    This paper reports US NRC-sponsored research at the Idaho National Engineering Laboratory (INEL) involving evaluation of computer-based diagnostic graphics. The specific targets of current evaluations are multivariate data display formats which may be used in Safety Parameter Display Systems (SPDS) being developed for nuclear power plant control rooms. The purpose of the work is to provide a basis for NRC action in regulating licensee SPDSs or later computer/cathode ray tube (CRT) applications in nuclear control rooms

  6. Simulation-based expert system for nuclear reactor control and diagnostics. Progress report

    International Nuclear Information System (INIS)

    Lee, J.C.; Martin, W.R.

    1986-01-01

    This research concerns the development of artificial intelligence (AI) techniques suitable for application to the diagnostics and control of nuclear power plant systems. The overall objective of the current effort is to build a prototype simulation-based expert system for diagnosing accidents in nuclear reactors. The system is being designed to analyze plant data heuristically using fuzzy logic to form a set of hypotheses about a particular transient. Hypothesis testing, fault magnitude estimation and transient analysis is performed using simulation programs to model plant behavior. An adaptive learning technique has been developed for achieving accurate simulations of plant dynamics using low-order physical models of plant components. The results of the diagnostics and simulation analysis of the plant transient are to be analyzed by an expert system for final diagnoses and control guidance. To date, significant progress has been made toward achieving the primary goals of this project. Based on a critical safety functions approach, an overall design for the nuclear plant expert system has been developed. The methodology for performing diagnostic reasoning on plant signals has been developed and the algorithms implemented and tested. A methodology for utilizing the information contained in the physical models of plant components has also been developed. This work included the derivation of a unique Kalman filtering algorithm for using power plant data to systematically improve on-line simulations through the judicious adjustment of key model parameters. A few simulation models of key plant components have been developed and implemented to demonstrate the method on a realistic accident scenario. The chosen transient is a loss of feed flow exasperated by a stuck open relief valve, similar to the initiating event of the Three Mile Island Unit 2 accident in 1979

  7. Integrated control and diagnostic system architectures for future installations

    International Nuclear Information System (INIS)

    Wood, R.; March-Leuba, J.

    2000-01-01

    Nuclear reactors of the 21st century will employ increasing levels of automation and fault tolerance to increase availability, reduce accident risk, and lower operating costs. Key developments in control algorithms, fault diagnostics, fault tolerance, and distributed communications are needed to implement the fully automated plant. It will be equally challenging to integrate developments in separate information and control fields into a cohesive system, which collectively achieves the overall goals of improved safety, reliability, maintainability, and cost-effectiveness. Under the Nuclear Energy Research Initiative (NERI), the US Department of Energy is sponsoring a project to address some of the technical issues involved in meeting the long-range goal of 21st century reactor control systems. This project involves researchers from Oak Ridge National Laboratory, the University of Tennessee, and North Carolina State University. The research tasks under this project focus on some of the first-level breakthroughs in control design, diagnostic techniques, and information system design that will provide a path to enable the design process to be automated in the future. This paper describes the conceptual development of an integrated nuclear plant control and information system architecture, which incorporates automated control system development that can be traced to a set of technical requirements. The expectation is that an integrated plant architecture with optimal control and efficient use of diagnostic information can reduce the potential for operational errors and minimize challenges to the plant safety systems

  8. Quality of reporting of diagnostic accuracy studies

    NARCIS (Netherlands)

    Smidt, N.; Rutjes, A.W.; Windt - Mens, van der D.A.W.M.; Ostelo, R.W.J.G.; Reitsma, J.B.; Bouter, L.M.; Vet, de H.C.W.

    2005-01-01

    PURPOSE: To evaluate quality of reporting in diagnostic accuracy articles published in 2000 in journals with impact factor of at least 4 by using items of Standards for Reporting of Diagnostic Accuracy (STARD) statement published later in 2003. MATERIALS AND METHODS: English-language articles on

  9. Plant databases and data analysis tools

    Science.gov (United States)

    It is anticipated that the coming years will see the generation of large datasets including diagnostic markers in several plant species with emphasis on crop plants. To use these datasets effectively in any plant breeding program, it is essential to have the information available via public database...

  10. Towards complete and accurate reporting of studies of diagnostic accuracy: The STARD initiative

    International Nuclear Information System (INIS)

    Bossuyt, P.M.; Reitsma, J.B.; Bruns, D.E.; Gatsonis, C.A.; Glasziou, P.P.; Irwig, L.M.; Lijmer, J.G.; Moher, D.; Rennie, D.; Vet, H.C.W. de

    2003-01-01

    AIM: To improve the accuracy and completeness of reporting of studies of diagnostic accuracy in order to allow readers to assess the potential for bias in a study and to evaluate the general isability of its results. METHODS: The standards for reporting of diagnostic accuracy (STARD) steering committee searched the literature to identify publications on the appropriate conduct and reporting of diagnostic studies and extracted potential items into an extensive list. Researchers, editors, and members of professional organisations shortened this list during a 2 day consensus meeting with the goal of developing a checklist and a generic flow diagram for studies of diagnostic accuracy. RESULTS: The search for published guidelines about diagnostic research yielded 33 previously published checklists, from which we extracted a list of 75 potential items. At the consensus meeting, participants shortened the list to a 25-item checklist, by using evidence whenever available. A prototype of a flow diagram provides information about the method of recruitment of patients, the order of test execution and the numbers of patients undergoing the test under evaluation, the reference standard, or both. CONCLUSIONS: Evaluation of research depends on complete and accurate reporting. If medical journals adopt the checklist and the flow diagram, the quality of reporting of studies of diagnostic accuracy should improve to the advantage of clinicians, researchers, reviewers, journals, and the public

  11. IGENPRO knowledge-based digital system for process transient diagnostics and management

    International Nuclear Information System (INIS)

    Morman, J.A.; Reifman, J.; Vitela, J.E.; Wei, T.Y.C.; Applequist, C.A.; Hippely, P.; Kuk, W.; Tsoukalas, L.H.

    1998-01-01

    Verification and validation issues have been perceived as important factors in the large scale deployment of knowledge-based digital systems for plant transient diagnostics and management. Research and development (R and D) is being performed on the IGENPRO package to resolve knowledge base issues. The IGENPRO approach is to structure the knowledge bases on generic thermal-hydraulic (T-H) first principles and not use the conventional event-basis structure. This allows for generic comprehensive knowledge, relatively small knowledge bases and above all the possibility of T-H system/plant independence. To demonstrate concept feasibility the knowledge structure has been implemented in the diagnostic module PRODIAG. Promising laboratory testing results have been obtained using data from the full scope Braidwood PWR operator training simulator. This knowledge structure is now being implemented in the transient management module PROMANA to treat unanticipated events and the PROTREN module is being developed to process actual plant data. Achievement of the IGENPRO R and D goals should contribute to the acceptance of knowledge-based digital systems for transient diagnostics and management. (author)

  12. IGENPRO knowledge-based digital system for process transient diagnostics and management

    International Nuclear Information System (INIS)

    Morman, J.A.; Reifman, J.; Wei, T.Y.C.

    1997-01-01

    Verification and validation issues have been perceived as important factors in the large scale deployment of knowledge-based digital systems for plant transient diagnostics and management. Research and development (R ampersand D) is being performed on the IGENPRO package to resolve knowledge base issues. The IGENPRO approach is to structure the knowledge bases on generic thermal-hydraulic (T-H) first principles and not use the conventional event-basis structure. This allows for generic comprehensive knowledge, relatively small knowledge bases and above all the possibility of T-H system/plant independence. To demonstrate concept feasibility the knowledge structure has been implemented in the diagnostic module PRODIAG. Promising laboratory testing results have been obtained using data from the full scope Braidwood PWR operator training simulator. This knowledge structure is now being implemented in the transient management module PROMANA to treat unanticipated events and the PROTREN module is being developed to process actual plant data. Achievement of the IGENPRO R ampersand D goals should contribute to the acceptance of knowledge-based digital systems for transient diagnostics and management

  13. Design of Diagnostics: Case Studies for Wendelstein 7-X

    International Nuclear Information System (INIS)

    Dreier, H.; Dinklage, A.; Fischer, R.; Hirsch, M.; Kornejew, P.; Pasch, E.

    2005-01-01

    The set of start-up diagnostics for Wendelstein 7-X is oriented to resolve physical issues of stellarator optimization [1]. The diagnostics philosophy of W7-X aims at extendable set-ups which are to be supplemented along the operation of the device. Planning diagnostics directly lead to the requirement to optimize their respective outcome. In many cases, the optimization is much restricted by technical constraints. But even in those cases, figures of robustness of the chosen design settings are beneficial for the diagnostic strategy. In this paper a framework for diagnostic design is presented employing the Bayesian probability theory. Part of the approach can be regarded as a virtual diagnostic, which describes the future experimental unit including its error statistics and is able to produce artificial data. The virtual diagnostic is fed with mock-up quantities of interest and hence it enables the designer to compare the outcome of the virtual diagnostic with its input. For the design of diagnostics in fusion experiments several figures of merit are possible, depend- ing on the optimization goal. Here physical questions like estimation of the density distribution or the density gradient are possible optimization targets as well as technical issues as the robustness of density measurements, e.g, for controlling purposes. Also the estimation of derived quantities - like gradients needed for modeling of the bootstrap current or of the radial electric field - might be considered to be the goal of a diagnostic design. (Author)

  14. Development of an equipment diagnostic system that evaluates sensor drift

    International Nuclear Information System (INIS)

    Kanada, Masaki; Arita, Setsuo; Tada, Nobuo; Yokota, Katsuo

    2011-01-01

    The importance of condition monitoring technology for equipment has increased with the introduction of condition-based maintenance in nuclear power plants. We are developing a diagnostic system using process signals for plant equipment, such as pumps and motors. It is important to enable the diagnostic system to distinguish sensor drift and equipment failure. We have developed a sensor drift diagnostic method that combines some highly correlative sensor signals by using the MT (Mahalanobis-Taguchi) method. Furthermore, we have developed an equipment failure diagnostic method that measures the Mahalanobis distance from the normal state of equipment by the MT method. These methods can respectively detect sensor drift and equipment failure, but there are the following problems. In the sensor drift diagnosis, there is a possibility of misjudging the sensor drift when the equipment failure occurs and the process signal changes because the behavior of the process signal is the same as that of the sensor drift. Oppositely, in the equipment failure diagnosis, there is a possibility of misjudging the equipment failure when the sensor drift occurs because the sensor drift influences the change of process signal. To solve these problems, we propose a diagnostic method combining the sensor drift diagnosis and the equipment failure diagnosis by the MT method. Firstly, the sensor drift values are estimated by the sensor drift diagnosis, and the sensor drift is removed from the process signal. It is necessary to judge the validity of the estimated sensor drift values before removing the sensor drift from the process signal. We developed a method for judging the validity of the estimated sensor drift values by using the drift distribution based on the sensor calibration data. And then, the equipment failure is diagnosed by using the process signals after removal of the sensor drifts. To verify the developed diagnostic system, several sets of simulation data based on abnormal cases

  15. GPs' perspectives on the diagnostic work-up in patients with shoulder pain: a qualitative study.

    Science.gov (United States)

    Ottenheijm, Ramon P G; Hesselmans, Nicolle J J M; Kemper, Anouk; Moser, Albine; de Bie, Rob A; Dinant, Geert-Jan; Cals, Jochen W L

    2014-06-01

    The diagnostic work-up of patients with shoulder pain in general practice is complex. General practitioners' (GPs) guidelines advise a pragmatic diagnostic work-up in which additional imaging has a limited role. However, diagnostic ultrasounds are increasingly ordered by GPs, which seems to reflect complexity in management of shoulder pain. This study aimed to explore GPs' perspectives on the diagnostic work-up of patients with shoulder pain. This study has a qualitative exploratory design with an inductive approach and was carried out in Dutch general practice. The study population consisted of 18 Dutch GPs who were sampled purposefully with a spread in clinical experience and ordering diagnostic ultrasound. Data were gathered by means of semi-structured interviews and analysed following principles of the constant comparative method. Three main categories with subcategories emerged that captured the diagnostic work-up of shoulder pain: variety in diagnostic classifications [(non-)specific diagnosis and interdisciplinary differences], establishing strategies for diagnostic work-up (use of existing tools and motives to deviate from existing tools), and strategies dealing with diagnostic uncertainties (accepting diagnostic uncertainties, diagnostic imaging tests, and interdisciplinary consultation and referral). Despite the availability of evidence-based shoulder guidelines, GPs experience uncertainties during diagnostic work-up and apply different strategies when dealing with these uncertainties. At some point, GPs as well as patients seem to have a need for a specific diagnosis. Currently, there appears to be little agreement if, or in which phase of shoulder pain, diagnostic ultrasound is useful or indicated. © 2014 John Wiley & Sons, Ltd.

  16. Diagnostics aid for mass spectrometer trouble-shooting

    International Nuclear Information System (INIS)

    Filby, E.E.; Rankin, R.A.; Webb, G.W.

    1987-01-01

    The ''MS Expert'' system provides problem diagnostics for instruments used in the Mass Spectrometry Laboratory (MSL). The most critical results generated on these mass spectrometers are the uranium concentration and isotopic content data used for process control and materials accountability at the Idaho Chemical Processing Plant. The two purposes of the system are: (1) to minimize instrument downtime and thereby provide the best possible support to the Plant, and (2) to improve long-term data quality. This system combines the knowledge of several experts on mass spectrometry to provide a diagnostic tool, and can make these skills avilable on a more timely basis. It integrates code written in the Pascal language with a knowledge base entered into a commercial expert system ''shell.'' The user performs some preliminary status checks, and then selects from among several broad diagnostic categories. These initial steps provide input to the rule base. The overall analysis provides the user with a set of possible solutions to the observed problems, graded as to their probabilities. Besides the trouble-shooting benefits expected from this system, it will also provide structures diagnostic training for lab personnel. In addition, development of the system knowledge base has already produced a better understanding of instrument behavior. Two key findings are that a good user interface is necessary for full acceptance of the tool, and a development system should include standard programming capabilities as well as the expert system shell. 22 refs., 5 figs

  17. Diagnostics aid for mass spectrometer trouble-shooting

    International Nuclear Information System (INIS)

    Filby, E.E.; Rankin, R.A.; Webb, G.W.

    1987-01-01

    The MS Expert system provides problem diagnostics for instruments used in the Mass Spectrometry Laboratory (MSL). The most critical results generated on these mass spectrometers are the uranium concentration and isotopic content data used for process control and materials accountability at the Idaho General Processing Plant. The two purposes of the system are: (1) to minimize instrument downtime and thereby provide the best possible support to the Plant, and (2) to improve long-term data quality. This system combines the knowledge of several experts on mass spectrometry to provide a diagnostic tool, and can make these skills available on a more timely basis. It integrates code written in the Pascal language with a knowledge base entered into a commercial expert system shell. The user performs some preliminary status checks, and then selects from among several broad diagnostic categories. These initial steps provide input to the rule base. The overall analysis provides the user with a set of possible solutions to the observed problems, graded as to their probabilities. Besides the trouble-shooting benefits expected from this system, it also provides structured diagnostic training for lab personnel. In addition, development of the system knowledge base has already produced a better understanding of instrument behavior. Two key findings are that a good user interface is necessary for full acceptance of the tool, and, a development system should include standard programming capabilities as well as the expert system shell

  18. CIT diagnostic computer interface studies

    International Nuclear Information System (INIS)

    Rauch, W.; Hayes, S.; Lowrance, J.; Oliaro, G.; Sauthoff, N.; Sichta, P.; Stark, W.

    1987-01-01

    This paper presents the on-going work performed in proposing instrumentation equipment and communications networks for the Diagnostic Data Acquisition and Diagnostic Instrumentation and Control System for the Compact Ignition Torus (CIT), which will begin operation in 1993. Consideration is given to the system criteria and requirements and their influence on the appropriate application of instrumentation and communication technologies to the system. This paper concentrates on the investigation of the bus communication technologies as they apply to the CIT data acquisition system. It compares CAMAC, VME, and FASTBUS as standards for data acquisition. The paper describes the connectivity between VAX equipment and CAMAC and VME instrumentation systems. Instrumentation and communication functionality and performance levels are presented as factors important to the overall data acquisition system performance

  19. A retrospective study of relevant diagnostic procedures in vulvodynia

    DEFF Research Database (Denmark)

    Petersen, Christina Damsted; Kristensen, Ellids; Lundvall, Lene

    2009-01-01

    OBJECTIVE: To identify objective clinical signs of vulvodynia and determine specific diagnostic tests for vulvodynia in women referred to a vulvar outpatient clinic for vulval complaints. STUDY DESIGN: A retrospective study was performed of the medical records of 201 consecutive Danish patients s...

  20. Concurrent and predictive evaluation of malnutrition diagnostic measures in hip fracture inpatients: a diagnostic accuracy study.

    Science.gov (United States)

    Bell, J J; Bauer, J D; Capra, S; Pulle, R C

    2014-03-01

    Differences in malnutrition diagnostic measures impact malnutrition prevalence and outcomes data in hip fracture. This study investigated the concurrent and predictive validity of commonly reported malnutrition diagnostic measures in patients admitted to a metropolitan hospital acute hip fracture unit. A prospective, consecutive level II diagnostic accuracy study (n=142; 8 exclusions) including the International Classification of Disease, 10th Revision, Australian Modification (ICD10-AM) protein-energy malnutrition criteria, a body mass index (BMI) Patients were predominantly elderly (median age 83.5, range 50-100 years), female (68%), multimorbid (median five comorbidities), with 15% 4-month mortality. Malnutrition prevalence was lowest when assessed by BMI (13%), followed by MNA-SF (27%), ICD10-AM (48%), albumin (53%) and geriatrician assessment (55%). Agreement between measures was highest between ICD10-AM and geriatrician assessment (κ=0.61) followed by ICD10-AM and MNA-SF measures (κ=0.34). ICD10-AM diagnosed malnutrition was the only measure associated with 48-h mobilisation (35.0 vs 55.3%; P=0.018). Reduced likelihood of home discharge was predicted by ICD-10-AM (20.6 vs 57.1%; P=0.001) and MNA-SF (18.8 vs 47.8%; P=0.035). Bivariate analysis demonstrated ICD10-AM (relative risk (RR)1.2; 1.05-1.42) and MNA-SF (RR1.2; 1.0-1.5) predicted 4-month mortality. When adjusted for age, usual place of residency, comorbidities and time to surgery only ICD-10AM criteria predicted mortality (odds ratio 3.59; 1.10-11.77). Albumin, BMI and geriatrician assessment demonstrated limited concurrent and predictive validity. Malnutrition prevalence in hip fracture varies substantially depending on the diagnostic measure applied. ICD-10AM criteria or the MNA-SF should be considered for the diagnosis of protein-energy malnutrition in frail, multi-morbid hip fracture inpatients.

  1. Adaptive Technology Application for Vibration-Based Diagnostics of Roller Bearings on Industrial Plants

    Directory of Open Access Journals (Sweden)

    Mironov Aleksey

    2014-09-01

    Full Text Available Roller bearings are widely used in equipment of different applications; therefore, the issues related to the assessment of bearing technical state and localization of bearing faults are quite important and relevant. The reason is that technical state of a bearing is a critical component, which determines efficiency of a mechanism or equipment. For bearings inspection and diagnostics, various methods of vibration-based diagnostics are used. The adaptive technology for vibration-based diagnostics developed in „D un D centrs” is an effective tool for evaluation of technical state of bearings in operation compared to the existing SKF method.

  2. Diagnostic stability among chronic patients with functional psychoses: an epidemiological and clinical study

    Directory of Open Access Journals (Sweden)

    Jakobsen Klaus D

    2007-08-01

    Full Text Available Abstract Background Diagnostic stability and illness course of chronic non-organic psychoses are complex phenomena and only few risk factors or predictors are known that can be used reliably. This study investigates the diagnostic stability during the entire course of illness in patients with non-organic psychoses and attempts to identify non-psychopathological risk factors or predictors. Method 100 patients with functional psychosis were initially characterised using the Operational Criteria Checklist for Psychotic Illness and Affective Illness (OPCRIT, medical records and health registers. To study the stability of diagnoses (i.e. shifts per time, we used registry data to define four measures of diagnostic variation that were subsequently examined in relation to four possible measures of time (i.e. observation periods or hospitalisation events. Afterwards, we identified putative co-variables and predictors of the best measures of diagnostic stability. Results All four measures of diagnostic variation are very strongly associated with numbers-of-hospitalisations and less so with duration-of-illness, duration-of-hospitalisation and with year-of-first-admission. The four measures of diagnostic variation corrected for numbers-of-hospitalisations were therefore used to study the diagnostic stability. Conventional predictors of illness course – e.g. age-of-onset and premorbid-functioning – are not significantly associated with stability. Only somatic-comorbidity is significantly associated with two measures of stability, while family-history-of-psychiatric-illness and global-assessment-of-functioning (GAF scale score show a trend. However, the traditional variables age-of-first-admission, civil-status, first-diagnosis-being-schizophrenia and somatic-comorbidity are able to explain two-fifth of the variation in numbers-of-hospitalisations. Conclusion Diagnostic stability is closely linked with the contact between patient and the healthcare system

  3. [Plant hydroponics and its application prospect in medicinal plants study].

    Science.gov (United States)

    Zeng, Yan; Guo, Lan-Ping; Huang, Lu-Qi; Sun, Yu-Zhang

    2007-03-01

    This article introduced the theorem and method of hydroponics. Some examples of studies in agriculture and forestry were presented, the effects of elements, environmental stress and hormones on physiology of medicinal plants by using hydroponics were analyzed. It also introduced the feasibility and advantage of hydroponics in intermediate propagation and allelopathy of medicinal plant. And finally it made the conclusion that the way of hydroponics would be widely used in medicinal plant study.

  4. An intelligent diagnostic aid (ida) based upon the simulated and operational experience

    International Nuclear Information System (INIS)

    Zuenkov, M.; Poletykin, A.; Marsiletti, M.

    1999-01-01

    A diagnostic system has been developed addressed to timely trouble shooting in process plants during all operational modes. The theory of this diagnostic system is related with the usage of learning methods for automatic generation of knowledge bases. This approach enables the conversion of 'cause to effect' relations into 'effect to possible causes' ones. As applied to technical diagnosis, this allows one to generate troubleshooting rules of the kind 'symptoms to possible diagnosis' through 'failure to symptoms' relations. The problem of diagnostic rule generation is, thus, reduced to obtaining samples of the symptoms, that is the well known problem of failure modelling. The diagnostic rules are derived from the operation of a simulator according to the following procedure: (a) identification of all initiating events and of the corresponding operational modes; (b) simulation of all the selected transients for a time sufficient to identify the uniqueness of the plant response under each of the initiating event; (c) automatic generation of the set of diagnostic rules that, through the use of temporal logic and a filtering Expert System, associate the evolution of the process parameters and their derivatives to the initial perturbation. The plant model running under the simulator is built-up by means of the LEGO code. The LEGO code is a modular package developed at the Research and Development Department of the Italian National Electricity Board (CRA-ENEL) to facilitate modelling of the dynamics of fossil-fuelled and nuclear power plants. The LEGO code consists of a library of pre-programmed, pre-tested and pre-validated modules, that represent power plant components and a master program which allows the user to build-up a model by automatically interconnecting the modules in the arrangement determined by the modeler. The reference plant is Sampierdarena power station, that is a combined cycle plant dedicated to produce both electrical and heat power. The following

  5. Handbook of technical diagnostics fundamentals and application to structures and systems

    CERN Document Server

    2013-01-01

    This book presents concepts, methods and techniques to examine symptoms of faults and failures of structures, systems and components and to monitor functional performance and structural integrity. The book is organized in five parts. Part A introduces the scope and application of technical diagnostics and gives a comprehensive overview of the physics of failure. Part B presents all relevant methods and techniques for diagnostics and monitoring: from stress, strain, vibration analysis, nondestructive evaluation, thermography and industrial radiology to computed tomography and subsurface microstructural analysis. Part C cores the principles and concepts of technical failure analysis, illustrates case studies, and outlines machinery diagnostics with an emphasis on tribological systems. Part D describes the application of structural health monitoring and performance control to plants and the technical infrastructure, including buildings, bridges, pipelines, electric power stations, offshore wind structures, and r...

  6. A study on the fault diagnostic techniques for reactor internal structures using neutron noise analysis

    International Nuclear Information System (INIS)

    Kim, Tae Ryong; Jeong, Seong Ho; Park, Jin Ho; Park, Jin Suk

    1994-08-01

    The unfavorable phenomena, such as flow induced vibration and aging process in reactor internals, cause degradation of structural integrity and may result in loosing some mechanical binding components which might impact other equipments and components or cause flow blockage. Since these malfunctions and potential failures change reactor noise signal, it is necessary to analyze reactor noise signal for early fault diagnosis in the point of few of safety and plant economics. The objectives of this study are to establish fault diagnostic and TS(thermal shield), and to develop a data acquisition and signal processing software system. In the first year of this study, an analysis technique for the reactor internal vibration using the reactor noise was proposed. With the technique proposed and the reactor noise signals (ex-core neutron and acceleration), the dynamic characteristics of Ulchin-1 reactor internals were obtained, and compared with those of Tricastin-1 which is the prototype of Ulchin-1. In the second year, a PC-based expert system for reactor internals fault diagnosis is developed, which included data acquisition, signal processing, feature extraction function, and represented diagnostic knowledge by the IF-THEN rule. To know the effect of the faults, the reactor internals of Ulchin-1 is modeled using FEM and simulated with an artificial defect given in the hold-down spring. Trend in the dynamic characteristics of reactor internals is also observed during one fuel cycle to know the effect of boron concentration. 100 figs, 7 tabs, 18 refs. (Author)

  7. School Psychologist Diagnostic Decision-Making: A Pilot Study

    Science.gov (United States)

    Barnard-Brak, Lucy; Stevens, Tara; Robinson, Eric; Holt, Ann

    2013-01-01

    The current study examined the diagnostic decision-making of school psychologists as a function of a student's disability and academic performance with three research questions using a randomly-selected sample of school psychologists from the state of Texas. Results from the first research question indicated that school psychologists significantly…

  8. Advanced diagnostics for laser plasma interaction studies and some recent experiments

    International Nuclear Information System (INIS)

    Chaurasia, S.; Munda, D.S.; Dhareshwar, L.J.

    2008-10-01

    The complete characterization of Laser plasma interaction studies related to inertial confinement fusion laser and Equation of state (EOS) studies needs many diagnostics to explain the several physical phenomena occurring simultaneously in the laser produced plasma. This involves many on ion emission are important to understand physical phenomena which are responsible for generation of laser plasma as well as its interaction with an intense laser. In this report we describe the development of various x-ray diagnostics which are used in determining temporal, spatial and spectral properties of x-rays radiated from laser produced plasma. Diagnostics which have been used in experiments for investigation of laser-produced plasma as a source of ions are also described. Techniques using an optical streak camera and VISAR which are being used in the Equation of States (EOS) studies of various materials, which are important for material science, astrophysics as well as ICF is described in details. (author)

  9. DIAGNOSTICS OF VIRUS PHYTOPATHOGENS FRUIT TREE PLUM POX VIRUS, PRUNUS NECROTIC RINGSPOT VIRUS AND PRUNUS DWARF VIRUS BY BIOLOGICAL AND MOLECULAR DIAGNOSTICS

    OpenAIRE

    Július Rozák; Zdenka Gálová

    2013-01-01

    The aim of this study was to determine the incidence of viral phytopathogen Plum pox virus, Prunus necrotic ringspot virus and Prunus dwarf virus in selected localities of Slovakia and diagnose them using a molecular and biological methods. Forty samples of fruit trees of the genus Prunus, twenty samples from intensive plantings and twenty samples from wild subject were analysed. Biological diagnostic by using biological indicators Prunus persica cv. GF 305, Prunus serrulata cv. Schirofugen a...

  10. Intelligent distributed control for nuclear power plants

    International Nuclear Information System (INIS)

    Klevans, E.H.

    1993-01-01

    This project was initiated in September 1989 as a three year project to develop and demonstrate Intelligent Distributed Control (IDC) for Nuclear Power Plants. There were two primary goals of this research project. The first goal was to combine diagnostics and control to achieve a highly automated power plant as described by M.A. Schultz. The second goal was to apply this research to develop a prototype demonstration on an actual power plant system, the EBR-2 steam plant. Described in this Final (Third Annual) Technical Progress Report is the accomplishment of the project's final milestone, an in-plant intelligent control experiment conducted on April 1, 1993. The development of the experiment included: simulation validation, experiment formulation and final programming, procedure development and approval, and experimental results. Other third year developments summarized in this report are: (1) a theoretical foundation for Reconfigurable Hybrid Supervisory Control, (2) a steam plant diagnostic system, (3) control console design tools and (4) other advanced and intelligent control

  11. A study of diagnostic imaging in pancreatic trauma

    International Nuclear Information System (INIS)

    Hirota, Masashi; Kanazumi, Naohito; Kato, Koichi; Eguchi, Takehiko; Kobayashi, Hironobu; Suzuki, Yuichi; Kimura, Jiro; Ishii, Masataka

    2002-01-01

    Pancreatic trauma treatment depends on pancreatic ductal injury. We examined the usefulness and problems of diagnostic imaging, such as enhanced CT, ERP, and CT after ERP, in pancreatic trauma. Subjects were 12 patients with pancreatic trauma treated in our hospital between April 1993 and March 2000. Enhanced CT was performed in 6 patients undergoing diagnostic imagings and ERP in 4 of the 6. Overall diagnostic accuracy of pancreatic ductal injury in enhanced CT was 16.7% and accuracy in ERP with CT after ERP was 100%. Intraoperative diagnosis of main pancreatic ductal injury was difficult in 1 of 2 patients in whom ERP failed. The importance of preoperative diagnostic imaging is thus clear. We expect that MRCP, recently evaluated in pancreatic disease diagnosis, will become a new pancreatic trauma modality. (author)

  12. Development of a majority vote decision module for a self-diagnostic monitoring system for an air-operated valve system

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Woo Shin [Dept. of Information and Communication Engineering, Sejong University, Seoul (Korea, Republic of); Chai, Jang Bom [Dept. of Mechanical Engineering, Ajou University, Suwon (Korea, Republic of); Kim, In Taek [Dept. of Information and Communication Engineering, Myongji University, Yongin (Korea, Republic of)

    2015-08-15

    A self-diagnostic monitoring system is a system that has the ability to measure various physical quantities such as temperature, pressure, or acceleration from sensors scattered over a mechanical system such as a power plant, in order to monitor its various states, and to make a decision about its health status. We have developed a self-diagnostic monitoring system for an air-operated valve system to be used in a nuclear power plant. In this study, we have tried to improve the self-diagnostic monitoring system to increase its reliability. We have implemented three different machine learning algorithms, i.e., logistic regression, an artificial neural network, and a support vector machine. After each algorithm performs the decision process independently, the decision-making module collects these individual decisions and makes a final decision using a majority vote scheme. With this, we performed some simulations and presented some of its results. The contribution of this study is that, by employing more robust and stable algorithms, each of the algorithms performs the recognition task more accurately. Moreover, by integrating these results and employing the majority vote scheme, we can make a definite decision, which makes the self-diagnostic monitoring system more reliable.

  13. Development of a majority vote decision module for a self-diagnostic monitoring system for an air-operated valve system

    International Nuclear Information System (INIS)

    Kim, Woo Shin; Chai, Jang Bom; Kim, In Taek

    2015-01-01

    A self-diagnostic monitoring system is a system that has the ability to measure various physical quantities such as temperature, pressure, or acceleration from sensors scattered over a mechanical system such as a power plant, in order to monitor its various states, and to make a decision about its health status. We have developed a self-diagnostic monitoring system for an air-operated valve system to be used in a nuclear power plant. In this study, we have tried to improve the self-diagnostic monitoring system to increase its reliability. We have implemented three different machine learning algorithms, i.e., logistic regression, an artificial neural network, and a support vector machine. After each algorithm performs the decision process independently, the decision-making module collects these individual decisions and makes a final decision using a majority vote scheme. With this, we performed some simulations and presented some of its results. The contribution of this study is that, by employing more robust and stable algorithms, each of the algorithms performs the recognition task more accurately. Moreover, by integrating these results and employing the majority vote scheme, we can make a definite decision, which makes the self-diagnostic monitoring system more reliable

  14. Diagnostic accuracy research in glaucoma is still incompletely reported: An application of Standards for Reporting of Diagnostic Accuracy Studies (STARD 2015.

    Directory of Open Access Journals (Sweden)

    Manuele Michelessi

    Full Text Available Research has shown a modest adherence of diagnostic test accuracy (DTA studies in glaucoma to the Standards for Reporting of Diagnostic Accuracy Studies (STARD. We have applied the updated 30-item STARD 2015 checklist to a set of studies included in a Cochrane DTA systematic review of imaging tools for diagnosing manifest glaucoma.Three pairs of reviewers, including one senior reviewer who assessed all studies, independently checked the adherence of each study to STARD 2015. Adherence was analyzed on an individual-item basis. Logistic regression was used to evaluate the effect of publication year and impact factor on adherence.We included 106 DTA studies, published between 2003-2014 in journals with a median impact factor of 2.6. Overall adherence was 54.1% for 3,286 individual rating across 31 items, with a mean of 16.8 (SD: 3.1; range 8-23 items per study. Large variability in adherence to reporting standards was detected across individual STARD 2015 items, ranging from 0 to 100%. Nine items (1: identification as diagnostic accuracy study in title/abstract; 6: eligibility criteria; 10: index test (a and reference standard (b definition; 12: cut-off definitions for index test (a and reference standard (b; 14: estimation of diagnostic accuracy measures; 21a: severity spectrum of diseased; 23: cross-tabulation of the index and reference standard results were adequately reported in more than 90% of the studies. Conversely, 10 items (3: scientific and clinical background of the index test; 11: rationale for the reference standard; 13b: blinding of index test results; 17: analyses of variability; 18; sample size calculation; 19: study flow diagram; 20: baseline characteristics of participants; 28: registration number and registry; 29: availability of study protocol; 30: sources of funding were adequately reported in less than 30% of the studies. Only four items showed a statistically significant improvement over time: missing data (16, baseline

  15. Performance diagnostic system for emergency diesel generators

    International Nuclear Information System (INIS)

    Logan, K.P.

    1991-01-01

    Diesel generators are commonly used for emergency backup power at nuclear stations. Emergency diesel generators (EDGs) are subject to both start-up and operating failures, due to infrequent and fast-start use. EDG reliability can be critical to plant safety, particularly when station blackout occurs. This paper describes an expert diagnostic system designed to consistently evaluate the operating performance of diesel generators. The prototype system is comprised of a suite of sensor monitoring, cylinder combustion analyzing, and diagnostic workstation computers. On-demand assessments of generator and auxiliary equipment performance are provided along with color trend displays comparing measured performance to reference-normal conditions

  16. MODIFIED ALVARADO SCORING AS A DIAGNOSTIC TOOL IN ACUTE APPENDICITIS- A PROSPECTIVE STUDY

    Directory of Open Access Journals (Sweden)

    V. K. Arun Kumar

    2017-02-01

    Full Text Available BACKGROUND Acute Appendicitis commonest community-acquired intra-abdominal infections. Acute appendicitis and its associated complications are significant source of morbidity and sometimes mortality. The Modified Alvarado Scoring System (MASS has been reported to be a cheap and quick diagnostic tool in patients with acute appendicitis. Diagnostic accuracy have been observed if the scores were applied to various populations and clinical settings. The purpose of this study was to evaluate the diagnostic value of Modified Alvarado Scoring System in patients with acute appendicitis in our setting. The aim of the study is to evaluate the efficacy of the modified Alvarado score as a diagnostic tool in Acute Appendicitis, as the diagnosis of appendicitis depends on the onset of symptoms and the subjective interpretation of the physical examination. MATERIALS AND METHODS This was a prospective study carried out in Pondicherry Institute of Medical Science during the period of November 2013 to May 2015. This study was done on 50 patients diagnosed with Acute Appendicitis and admitted in General Surgery. RESULTS In this study, there were a total of 50 patients who were taken up for surgery based on clinical and radiological diagnosis. Our study demonstrates that modified Alvarado score applied to all adult patients of acute appendicitis in adults with a sensitivity of 60% and a specificity of 40% only. Showing it wasn’t efficient in diagnosing acute appendicitis. The positive predictive value shown by our study was 80% which is marginally lower than that explained in literature which reports 87.5%. Negative appendicectomy rate in this study is 12%. CONCLUSION Alvarado score is a non-invasive, safe diagnostic procedure, which is simple, fast reliable and repeatable; it can be used in all conditions, without expensive and complicated supportive diagnostic methods. Alvarado score increases the diagnostic certainty of clinical examination in diagnosis of

  17. Using Meta-Analysis to Inform the Design of Subsequent Studies of Diagnostic Test Accuracy

    Science.gov (United States)

    Hinchliffe, Sally R.; Crowther, Michael J.; Phillips, Robert S.; Sutton, Alex J.

    2013-01-01

    An individual diagnostic accuracy study rarely provides enough information to make conclusive recommendations about the accuracy of a diagnostic test; particularly when the study is small. Meta-analysis methods provide a way of combining information from multiple studies, reducing uncertainty in the result and hopefully providing substantial…

  18. Problems of steam turbine diagnostics and the 'Simens' diagnosis system

    International Nuclear Information System (INIS)

    Tserner, V.; Andrea, K.

    1993-01-01

    Diagnostics system, allowing one to detect changes in the state on single turbine elements at an early stage is described. Besides this system allows one to utilize the turbine plant optimally and efficiency from the viewpoint of the equipment durability. Specially oriented monitoring of the turbine plant and equipment element state saves resources necessary to keep up the working order of the equipment

  19. Air-operated valve diagnostics: requirements, programmes and experiences

    International Nuclear Information System (INIS)

    Cervilla, Remedios; Vallana, Fernando; Laporta, Jose Maria

    2014-01-01

    The aim of this paper is to present some elements in the field of air-operated valve (AOV) diagnostics from the perspective of Tecnatom, as a testing services provider in the national and international nuclear park. Throughout the following lines, we summarize the regulatory framework existing in Spain and the current practices in Spanish nuclear power plants regarding the AOV programs, the role of Tecnatom as a service provider and our testing techniques. Finally, a real test case is presented, to illustrate the value of diagnostic as predictive maintenance and early degradation detection tool. (authors)

  20. Diagnostics for studies of novel laser ion acceleration mechanisms

    Energy Technology Data Exchange (ETDEWEB)

    Senje, Lovisa; Aurand, Bastian; Wahlström, Claes-Göran [Department of Physics, Lund University, P. O. Box 118, S-221 00 Lund (Sweden); Yeung, Mark; Kuschel, Stephan; Rödel, Christian [Helmholtz-Institut Jena, D-07743 Jena (Germany); Wagner, Florian; Roth, Markus [Technische Universität Darmstadt, D-64289 Darmstadt (Germany); Li, Kun; Neumayer, Paul [ExtreMe Matter Institut, D-64291 Darmstadt (Germany); Dromey, Brendan; Jung, Daniel [Department of Physics and Astronomy, Queen' s University, Belfast BT7 1NN (United Kingdom); Bagnoud, Vincent [Helmholtz-Institut Jena, D-07743 Jena (Germany); GSI Helmholtzzentrum für Schwerionenforschung GmbH, D-64291 Darmstadt (Germany); Zepf, Matthew [Helmholtz-Institut Jena, D-07743 Jena (Germany); Department of Physics and Astronomy, Queen' s University, Belfast BT7 1NN (United Kingdom); Kuehl, Thomas [ExtreMe Matter Institut, D-64291 Darmstadt (Germany); GSI Helmholtzzentrum für Schwerionenforschung GmbH, D-64291 Darmstadt (Germany); Universität Mainz, D-55099 Mainz (Germany)

    2014-11-15

    Diagnostic for investigating and distinguishing different laser ion acceleration mechanisms has been developed and successfully tested. An ion separation wide angle spectrometer can simultaneously investigate three important aspects of the laser plasma interaction: (1) acquire angularly resolved energy spectra for two ion species, (2) obtain ion energy spectra for multiple species, separated according to their charge to mass ratio, along selected axes, and (3) collect laser radiation reflected from and transmitted through the target and propagating in the same direction as the ion beam. Thus, the presented diagnostic constitutes a highly adaptable tool for accurately studying novel acceleration mechanisms in terms of their angular energy distribution, conversion efficiency, and plasma density evolution.

  1. Diagnostics for studies of novel laser ion acceleration mechanisms

    International Nuclear Information System (INIS)

    Senje, Lovisa; Aurand, Bastian; Wahlström, Claes-Göran; Yeung, Mark; Kuschel, Stephan; Rödel, Christian; Wagner, Florian; Roth, Markus; Li, Kun; Neumayer, Paul; Dromey, Brendan; Jung, Daniel; Bagnoud, Vincent; Zepf, Matthew; Kuehl, Thomas

    2014-01-01

    Diagnostic for investigating and distinguishing different laser ion acceleration mechanisms has been developed and successfully tested. An ion separation wide angle spectrometer can simultaneously investigate three important aspects of the laser plasma interaction: (1) acquire angularly resolved energy spectra for two ion species, (2) obtain ion energy spectra for multiple species, separated according to their charge to mass ratio, along selected axes, and (3) collect laser radiation reflected from and transmitted through the target and propagating in the same direction as the ion beam. Thus, the presented diagnostic constitutes a highly adaptable tool for accurately studying novel acceleration mechanisms in terms of their angular energy distribution, conversion efficiency, and plasma density evolution

  2. Diagnostics of nitrogen deficiency in mini-cucumber plant by near ...

    African Journals Online (AJOL)

    K-nearest neighbors (KNN) and artificial neural network (ANN) were applied to build diagnostics models, respectively. Some parameters of the model were optimized by cross-validation. The performance of the KNN model and the ANN model based on NIRS data was compared. Experiment results showed that the ANN ...

  3. Plant Vogtle cooling tower studies

    International Nuclear Information System (INIS)

    O'Steen, L.

    2000-01-01

    Intensive ground-based field studies of plumes from two large, natural-draft cooling towers were conducted in support of the MTI modeling effort. Panchromatic imagery, IR imagery, meteorological data, internal tower temperatures and plant power data were collected during the field studies. These data were used to evaluate plume simulations, plume radioactive transfer calculations and plume volume estimation algorithms used for power estimation. Results from six field studies indicate that a 3-D atmospheric model at sufficient spatial resolution can effectively simulate a cooling tower plume if the plume is of sufficient size and the ambient meteorology is known and steady. Small plumes and gusty wind conditions degrade the agreement between the simulated and observed plumes. Thermal radiance calculations based on the simulated plumes produced maximum IR temperatures (near tower exit) which were in good agreement with measured IR temperatures for the larger plumes. For the smaller plumes, the calculated IR temperature was lower than the measured temperature by several degrees. Variations in maximum IR plume temperature with decreasing power (one reactor was undergoing a shutdown process), were clearly observed in the IR imagery and seen in the simulations. These temperature changes agreed with those calculated from an overall tower energy and momentum balance. Plume volume estimates based on camcorder images at three look angles were typically 20--30 percent larger than the plume volumes derived from the simulations, although one estimate was twice the simulated volume. Volume overestimation is expected and will have to be accounted for to some degree if plume volume is to be a useful diagnostic quantity in power estimation. Volume estimation with MTI imagery will require a large, stable plume and two looks in the visible bands (5m GSD) along with a solar shadow

  4. Artificial intelligence applications to nuclear reactor diagnostics

    International Nuclear Information System (INIS)

    Lee, J.C.; Hassberger, J.A.; Wehe, D.K.

    1987-01-01

    The authors research into applications of artificial intelligence to nuclear reactor diagnostics involves three main areas. In the first area, the authors combine reactor simulation models and expert systems to diagnose the state of the plant. The second area examines ways in which the rule or knowledge base of an intelligent controller can be generated systematically from either fault trees or acquired plant data. Third, efforts are described to develop the capabilities to validate these techniques in a realistic reactor setting. The techniques are applicable to all reactor types, including fast reactors

  5. Plant automation

    International Nuclear Information System (INIS)

    Christensen, L.J.; Sackett, J.I.; Dayal, Y.; Wagner, W.K.

    1989-01-01

    This paper describes work at EBR-II in the development and demonstration of new control equipment and methods and associated schemes for plant prognosis, diagnosis, and automation. The development work has attracted the interest of other national laboratories, universities, and commercial companies. New initiatives include use of new control strategies, expert systems, advanced diagnostics, and operator displays. The unique opportunity offered by EBR-II is as a test bed where a total integrated approach to automatic reactor control can be directly tested under real power plant conditions

  6. A diagnostic expert system for NPP based on hybrid knowledge approach

    International Nuclear Information System (INIS)

    Yang, Joon On; Chang, Soon Heung

    1989-01-01

    This paper describes a diagnostic expert system, HYPOSS (Hybrid Knowledge Based Plant Operation Supporting System), which has been developed to support operators' decision making during the transients of nuclear power plant. HYPOSS adopts the hybrid knowledge approach which combines shallow and deep knowledge to couple the merits of both approaches. In HYPOSS, four types of knowledge are used according to the steps of diagnosis procedure: structural, functional, behavioral and heuristic knowledge. The structural and functional knowledge is represented by three fundamental primitives and five types of functions respectively. The behavioral knowledge is represented using constraints. The inference procedure is based on the human problem solving behavior modeled in HYPOSS. For the validation of HYPOSS, several tests have been performed based on the data produced by a plant simulator. The results of validation studies showed a good applicability of HYPOSS to the anomaly diagnosis of nuclear power plant

  7. Isotopes in soil-plant nutrition studies

    International Nuclear Information System (INIS)

    1962-01-01

    Radioisotopes have greatly facilitated investigating the characteristics of plant nutrients in the soil, in measuring soil moisture, in studying the uptake of nutrients by plants and in devising efficient methods of fertilizer application, and are now being widely used in soil-plant nutrition research. A recent international symposium on the use of radioisotopes in soil-plant nutrition studies showed the varied ways in which isotopes can contribute to agricultural production by helping to investigate soil characteristics and soil-plant relationships. The symposium, jointly sponsored by the International Atomic Energy Agency and the Food and Agriculture Organization of the United Nations, was held in Bombay from 26 February to 2 March 1962, at the invitation of the Government of India

  8. Awareness of Diagnostic Error among Japanese Residents: a Nationwide Study.

    Science.gov (United States)

    Nishizaki, Yuji; Shinozaki, Tomohiro; Kinoshita, Kensuke; Shimizu, Taro; Tokuda, Yasuharu

    2018-04-01

    Residents' understanding of diagnostic error may differ between countries. We sought to explore the relationship between diagnostic error knowledge and self-study, clinical knowledge, and experience. Our nationwide study involved postgraduate year 1 and 2 (PGY-1 and -2) Japanese residents. The Diagnostic Error Knowledge Assessment Test (D-KAT) and General Medicine In-Training Examination (GM-ITE) were administered at the end of the 2014 academic year. D-KAT scores were compared with the benchmark scores of US residents. Associations between D-KAT score and gender, PGY, emergency department (ED) rotations per month, mean number of inpatients handled at any given time, and mean daily minutes of self-study were also analyzed, both with and without adjusting for GM-ITE scores. Student's t test was used for comparisons with linear mixed models and structural equation models (SEM) to explore associations with D-KAT or GM-ITE scores. The mean D-KAT score among Japanese PGY-2 residents was significantly lower than that of their US PGY-2 counterparts (6.2 vs. 8.3, p ITE scores correlated with ED rotations (≥6 rotations: 2.14; 0.16-4.13; p = 0.03), inpatient caseloads (5-9 patients: 1.79; 0.82-2.76; p ITE scores (ß = 0.37, 95% CI: 0.34-0.41) and indirectly associated with ED rotations (ß = 0.06, 95% CI: 0.02-0.10), inpatient caseload (ß = 0.04, 95% CI: 0.003-0.08), and average daily minutes of study (ß = 0.13, 95% CI: 0.09-0.17). Knowledge regarding diagnostic error among Japanese residents was poor compared with that among US residents. D-KAT scores correlated strongly with GM-ITE scores, and the latter scores were positively associated with a greater number of ED rotations, larger caseload (though only up to 15 patients), and more time spent studying.

  9. Haploid rice plants in mutation studies

    Energy Technology Data Exchange (ETDEWEB)

    Tanaka, S [Institute of Radiation Breeding, Ministry of Agriculture and Forestry, Ohmiya, Ibaraki-ken (Japan)

    1970-03-01

    Studies were made on chlorophyll-deficient sectors and diploid-like sectors in haploid rice plants exposed to chronic gamma irradiation, and on germinal mutations in diploid strains derived from the haploid plants. The induction and elimination of somatic mutations in haploid plants and the occurrence of drastic germinal mutations in diploid strains from haploid plants are discussed. (author)

  10. Statistical physics of medical diagnostics: Study of a probabilistic model.

    Science.gov (United States)

    Mashaghi, Alireza; Ramezanpour, Abolfazl

    2018-03-01

    We study a diagnostic strategy which is based on the anticipation of the diagnostic process by simulation of the dynamical process starting from the initial findings. We show that such a strategy could result in more accurate diagnoses compared to a strategy that is solely based on the direct implications of the initial observations. We demonstrate this by employing the mean-field approximation of statistical physics to compute the posterior disease probabilities for a given subset of observed signs (symptoms) in a probabilistic model of signs and diseases. A Monte Carlo optimization algorithm is then used to maximize an objective function of the sequence of observations, which favors the more decisive observations resulting in more polarized disease probabilities. We see how the observed signs change the nature of the macroscopic (Gibbs) states of the sign and disease probability distributions. The structure of these macroscopic states in the configuration space of the variables affects the quality of any approximate inference algorithm (so the diagnostic performance) which tries to estimate the sign-disease marginal probabilities. In particular, we find that the simulation (or extrapolation) of the diagnostic process is helpful when the disease landscape is not trivial and the system undergoes a phase transition to an ordered phase.

  11. Statistical physics of medical diagnostics: Study of a probabilistic model

    Science.gov (United States)

    Mashaghi, Alireza; Ramezanpour, Abolfazl

    2018-03-01

    We study a diagnostic strategy which is based on the anticipation of the diagnostic process by simulation of the dynamical process starting from the initial findings. We show that such a strategy could result in more accurate diagnoses compared to a strategy that is solely based on the direct implications of the initial observations. We demonstrate this by employing the mean-field approximation of statistical physics to compute the posterior disease probabilities for a given subset of observed signs (symptoms) in a probabilistic model of signs and diseases. A Monte Carlo optimization algorithm is then used to maximize an objective function of the sequence of observations, which favors the more decisive observations resulting in more polarized disease probabilities. We see how the observed signs change the nature of the macroscopic (Gibbs) states of the sign and disease probability distributions. The structure of these macroscopic states in the configuration space of the variables affects the quality of any approximate inference algorithm (so the diagnostic performance) which tries to estimate the sign-disease marginal probabilities. In particular, we find that the simulation (or extrapolation) of the diagnostic process is helpful when the disease landscape is not trivial and the system undergoes a phase transition to an ordered phase.

  12. PVT Degradation Studies: Acoustic Diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Dib, Gerges [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Tucker, Brian J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Kouzes, Richard T. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Smith, Philip J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2017-04-01

    Under certain environmental conditions, polyvinyl toluene (PVT) plastic scintillator has been observed to undergo internal fogging. This document reports on a study of acoustic techniques to determine whether they can provide a diagnostic for the fogging of PVT. Different ultrasound techniques were employed for detecting the level of internal fogging in PVT, including wave velocity measurements, attenuation, nonlinear acoustics, and acoustic microscopy. The results indicate that there are linear relations between the wave velocity and wave attenuation with the level of internal fogging. The effects of fogging on ultrasound wave attenuation is further verified by acoustic microscopy imaging, where regions with fog in the specimen demonstration higher levels of attenuation compared to clear regions. Results from the nonlinear ultrasound measurements were inconclusive due to high sensitivities to transducer coupling and fixture variabilities.

  13. Diagnostic needs for fluctuations and transport studies

    International Nuclear Information System (INIS)

    Carreras, B.A.

    1992-01-01

    The identification of fundamental transport mechanisms in magnetically confined plasmas is a critical issue for the magnetic fusion program. Recent progress in understanding fluctuations and transport is well correlated with the development and use of new diagnostics, but there a great deal of information is still missing. Some of the required measurements are well beyond our present diagnostic capabilities, but some are within reach and could answer critical questions in this area of research. Some of these critical issues are discussed

  14. Leak detection by vibrational diagnostic methods

    International Nuclear Information System (INIS)

    Siklossy, P.

    1983-01-01

    The possibilities and methods of leak detection due to mechanical failures in nuclear power plants are reviewed on the basis of the literature. Great importance is attributed to vibrational diagnostic methods for their adventageous characteristics which enable them to become final leak detecting methods. The problems of noise analysis, e.g. leak detection by impact sound measurements, probe characteristics, gain problems, probe selection, off-line analysis and correlation functions, types of leak noises etc. are summarized. Leak detection based on noise analysis can be installed additionally to power plants. Its maintenance and testing is simple. On the other hand, it requires special training and measuring methods. (Sz.J.)

  15. Symptom based diagnostic system using artificial neural networks

    International Nuclear Information System (INIS)

    Santosh; Vinod, Gopika; Saraf, R.K.

    2003-01-01

    Nuclear power plant experiences a number of transients during its operations. In case of such an undesired plant condition generally known as an initiating event, the operator has to carry out diagnostic and corrective actions. The operator's response may be too late to mitigate or minimize the negative consequences in such scenarios. The objective of this work is to develop an operator support system based on artificial neural networks that will assist the operator to identify the initiating events at the earliest stages of their developments. A symptom based diagnostic system has been developed to investigate the initiating events. Neutral networks are utilized for carrying out the event identification by continuously monitoring process parameters. Whenever an event is detected, the system will display the necessary operator actions along with the initiating event. The system will also show the graphical trend of process parameters that are relevant to the event. This paper describes the features of the software that is used to monitor the reactor. (author)

  16. Remote operation and maintenance support services for nuclear power plants

    International Nuclear Information System (INIS)

    Yamamoto, Hiroki; Higuma, Koji; Shimizu, Shunichi; Sakuma, Masatake; Sonoda, Yukio; Kanemoto, Shigeru

    2004-01-01

    Toshiba Corporation constructed e-Toshiba Operating Plant Service (e-TOPS TM ) system and began remote operation and maintenance support service for nuclear power plants. The service put into practice remote operation and maintenance by harmony of information technologies such as internet and mobile, and nuclear power measurement/diagnostic technologies and security techniques. Outline of e-TOPS TM , remote-control service, -inspection system, -diagnostic service and technologies support service are explained. Construction, objects and application effects of e-TOPS TM , remote diagnostic system using image treatment techniques, construction of device record card control system are illustrated. (S.Y.)

  17. Overinterpretation and misreporting of diagnostic accuracy studies: evidence of "spin".

    Science.gov (United States)

    Ochodo, Eleanor A; de Haan, Margriet C; Reitsma, Johannes B; Hooft, Lotty; Bossuyt, Patrick M; Leeflang, Mariska M G

    2013-05-01

    To estimate the frequency of distorted presentation and overinterpretation of results in diagnostic accuracy studies. MEDLINE was searched for diagnostic accuracy studies published between January and June 2010 in journals with an impact factor of 4 or higher. Articles included were primary studies of the accuracy of one or more tests in which the results were compared with a clinical reference standard. Two authors scored each article independently by using a pretested data-extraction form to identify actual overinterpretation and practices that facilitate overinterpretation, such as incomplete reporting of study methods or the use of inappropriate methods (potential overinterpretation). The frequency of overinterpretation was estimated in all studies and in a subgroup of imaging studies. Of the 126 articles, 39 (31%; 95% confidence interval [CI]: 23, 39) contained a form of actual overinterpretation, including 29 (23%; 95% CI: 16, 30) with an overly optimistic abstract, 10 (8%; 96% CI: 3%, 13%) with a discrepancy between the study aim and conclusion, and eight with conclusions based on selected subgroups. In our analysis of potential overinterpretation, authors of 89% (95% CI: 83%, 94%) of the studies did not include a sample size calculation, 88% (95% CI: 82%, 94%) did not state a test hypothesis, and 57% (95% CI: 48%, 66%) did not report CIs of accuracy measurements. In 43% (95% CI: 34%, 52%) of studies, authors were unclear about the intended role of the test, and in 3% (95% CI: 0%, 6%) they used inappropriate statistical tests. A subgroup analysis of imaging studies showed 16 (30%; 95% CI: 17%, 43%) and 53 (100%; 95% CI: 92%, 100%) contained forms of actual and potential overinterpretation, respectively. Overinterpretation and misreporting of results in diagnostic accuracy studies is frequent in journals with high impact factors. http://radiology.rsna.org/lookup/suppl/doi:10.1148/radiol.12120527/-/DC1. © RSNA, 2013.

  18. Feasibility Study on a Neutral Beam Diagnostic Injector for TJ-II

    Energy Technology Data Exchange (ETDEWEB)

    McCarthy, K. J.; Balbin, R.; Lopez-Fraguas, A.

    2003-07-01

    A diagnostic neutral beam system is proposed for the TJ-II stellarator. The main goal of installing such a system in TJ-II is to increase the signal to noise ratio and provide spatial resolution in diagnostic systems based on Charge Exchange Recombination Spectroscopy and Neutral Particle Analysis, while also opening up new opportunities for physics studies in this magnetically confined plasma device. After outlining the unique characteristics of the TJ-II and reviewing available diagnostic injector systems, the compact system selected for TJ-II is presented together with estimates of the resulting increased signal levels Finally other important aspects are discussed, in particular its location and orientation, as well as possible solutions to avoid perturbing the TJ-II magnetic configurations in the heliac device. (Author) 31 refs.

  19. Feasibility Study on a Neutral Beam Diagnostic Injector for TJ-II

    International Nuclear Information System (INIS)

    McCarthy, K. J.; Balbin, R.; Lopez-Fraguas, A.

    2003-01-01

    A diagnostic neutral beam system is proposed for the TJ-II stellarator. The main goal of installing such a system in TJ-II is to increase the signal to noise ratio and provide spatial resolution in diagnostic systems based on Charge Exchange Recombination Spectroscopy and Neutral Particle Analysis, while also opening up new opportunities for physics studies in this magnetically confined plasma device. After outlining the unique characteristics of the TJ-II and reviewing available diagnostic injector systems, the compact system selected for TJ-II is presented together with estimates of the resulting increased signal levels Finally other important aspects are discussed, in particular its location and orientation, as well as possible solutions to avoid perturbing the TJ-II magnetic configurations in the heliac device. (Author) 31 refs

  20. Systematic construction of qualitative physics-based rules for process diagnostics

    International Nuclear Information System (INIS)

    Reifman, J.; Wei, T.Y.C.

    1995-01-01

    A novel first-principles-based expert system is proposed for on-line detection and identification of faulty component candidates during incipient off-normal process operations. The system performs function-oriented diagnostics and can be reused for diagnosing single-component failures in different processes and different plants through the provision of the appropriate process schematics information. The function-oriented and process-independent diagnostic features of the proposed expert system are achieved by constructing a knowledge base containing three distinct types of information, qualitative balance equation rules, functional classification of process components, and the process piping and instrumentation diagram. The various types of qualitative balance equation rules for processes utilizing single-phase liquids are derived and their usage is illustrated through simulation results of a realistic process in a nuclear power plant

  1. Irritable bowel syndrome--prognosis and diagnostic safety. A 5-year follow-up study

    DEFF Research Database (Denmark)

    Svendsen, Jesper Hastrup; Munck, L K; Andersen, J R

    1985-01-01

    The irritable bowel syndrome is the commonest diagnosis in gastroenterological clinics, although diagnostic criteria and investigatory programs vary. To elucidate the diagnostic safety and prognosis of the syndrome, a retrospective study was conducted. One hundred and twelve consecutive patients...... with irritable bowel syndrome as the final and only abdominal diagnosis in the period 1977-79 were followed up in 1984. Seventeen patients died during the follow-up period; two of these were considered diagnostic failures (chronic pancreatitis and pancreatic cancer). Of the remaining 95 patients, 93 were...

  2. The graphics-based human interface to the DISYS diagnostic/control guidance system at EBR-2

    International Nuclear Information System (INIS)

    Edwards, R.M.; Chavez, C.; Kamarthi, S.; Dharap, S.; Lindsay, R.W.; Staffon, J.

    1990-01-01

    An initial graphics based interface to the real-time DISYS diagnostic system has been developed using the multi-tasking capabilities of the UNIX operating system and X-Windows 11 Xlib graphics library. This system is interfaced to live plant data at the Experimental Breeder Reactor (EBR-2) for the Argon Cooling System of fuel handling operations and the steam plant. The interface includes an intelligent process schematic which highlights problematic components and sensors based on the results of the diagnostic computations. If further explanation of a faulted component is required, the user can call up a display of the diagnostic computations presented in a tree-like diagram. Numerical data on the process schematic and optional diagnostic tree are updated as new real-time data becomes available. The initial X-Windows 11 based interface will be further enhanced using VI Corporation DATAVIEWS graphical data base software. 5 refs., 6 figs

  3. Diagnostic system for process control at NPP Dukovany load follow

    International Nuclear Information System (INIS)

    Rubek, J.; Petruzela, I.

    1998-01-01

    The NPP Dukovany is being operated in the frequency control since 1996. In last year a project for the plant load follow has been developed. One part of the project is to install a diagnostic system for process control. At present the main control loops of the plant control system are regular tested after unit refuelling only. The functionality and control system parameter adjusting is tested by certificated procedures. This state is unsuitable in view of the plan load follow operation. The relevant operational modes are based on minimisation of influence on plant component life time and on achievement of planned unit parameters. Therefore it is necessary to provide testing of main control system parts in shorter time period. Mainly at time when the unit is really in load follow operation. The paper describes the diagnostic system for process control which will be at NPP Dukovany implemented. The principal of the system will be evaluation of real and expected changes of technological variables. The system utilises thermohydraulic relation among main technological variables and relation among controlled and manipulated variables. Outputs of the system will be used to operational staff support at the plant operation. It enables: determination of control system state, estimation and check of future control system state, early indication of the deviation of process from normal conditions, check of efficiency of operational staff intervention into plant control. The system gives the plant operator new information for the plant process control. Simultaneously the coupling of new system outputs on existing signalisation is solved. (author)

  4. STARD-BLCM: Standards for the Reporting of Diagnostic accuracy studies that use Bayesian Latent Class Models

    DEFF Research Database (Denmark)

    Kostoulas, Polychronis; Nielsen, Søren S.; Branscum, Adam J.

    2017-01-01

    The Standards for the Reporting of Diagnostic Accuracy (STARD) statement, which was recently updated to the STARD2015 statement, was developed to encourage complete and transparent reporting of test accuracy studies. Although STARD principles apply broadly, the checklist is limited to studies......-BLCM (Standards for Reporting of Diagnostic accuracy studies that use Bayesian Latent Class Models), will facilitate improved quality of reporting on the design, conduct and results of diagnostic accuracy studies that use Bayesian latent class models....

  5. Diagnostic approach to urinary tract infections in male general practice patients: a national surveillance study.

    NARCIS (Netherlands)

    Heijer, C.D.J. den; Dongen, M.C.J.M. van; Donker, G.A.; Stobberingh, E.E.

    2012-01-01

    Background: Diagnostic urinary tract infection (UTI) studies have primarily been performed among female patients. Aim: To create a diagnostic algorithm for male general practice patients suspected of UTI. Design and setting: Surveillance study in the Dutch Sentinel General Practice Network. Method:

  6. Review of operational aids for nuclear plant operators

    International Nuclear Information System (INIS)

    Kisner, R.A.

    1983-01-01

    Many approaches are being explored to improve the safety of nuclear plant operations. One approach is to supply high-quality, relevant information by means of computer-based diagnostic systems to assist plant operators in performing their operational and safety-related roles. The evaluation of operational aids to ensure safe plant operations is a necessary function of NRC. This work has two purposes: to collect limited data on a diversity of operational aids, and to provide a method for evaluating the safety implications of the functions of proposed operational aids. After a discussion of the method evaluation now under study, this paper outlines this data collection to date

  7. Vibration control, machine diagnostics

    International Nuclear Information System (INIS)

    1990-01-01

    Changing vibrations announce damage in the form of wear or cracks on components of, e.g., engine rotors, pumps, power plant turbo sets, rounding-up tools, or marine diesel engines. Therefore, machine diagnostics use frequency analyses, system tests, trend analyses as well as expert systems to localize or estimate the causes of these damages and malfunctions. Data acquisistion, including not only sensors, but also reliable and redundant data processing systems and analyzing systems, play an important role. The lectures pertaining to the data base are covered in detail. (DG) [de

  8. Potential of MALDI-TOF mass spectrometry as a rapid detection technique in plant pathology: identification of plant-associated microorganisms.

    Science.gov (United States)

    Ahmad, Faheem; Babalola, Olubukola O; Tak, Hamid I

    2012-09-01

    Plant diseases caused by plant pathogens substantially reduce crop production every year, resulting in massive economic losses throughout the world. Accurate detection and identification of plant pathogens is fundamental to plant pathogen diagnostics and, thus, plant disease management. Diagnostics and disease-management strategies require techniques to enable simultaneous detection and quantification of a wide range of pathogenic and non-pathogenic microorganisms. Over the past decade, rapid development of matrix-assisted laser-desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) techniques for characterization of microorganisms has enabled substantially improved detection and identification of microorganisms. In the biological sciences, MALDI-TOF MS is used to analyze specific peptides or proteins directly desorbed from intact bacteria, fungal spores, nematodes, and other microorganisms. The ability to record biomarker ions, in a broad m/z range, which are unique to and representative of individual microorganisms, forms the basis of taxonomic identification of microorganisms by MALDI-TOF MS. Recent advances in mass spectrometry have initiated new research, i.e. analysis of more complex microbial communities. Such studies are just beginning but have great potential for elucidation not only of the interactions between microorganisms and their host plants but also those among different microbial taxa living in association with plants. There has been a recent effort by the mass spectrometry community to make data from large scale mass spectrometry experiments publicly available in the form of a centralized repository. Such a resource could enable the use of MALDI-TOF MS as a universal technique for detection of plant pathogens and non-pathogens. The effects of experimental conditions are sufficiently understood, reproducible spectra can be obtained from computational database search, and microorganisms can be rapidly characterized by genus, species

  9. Real-Time Adaptive Algorithms for Flight Control Diagnostics and Prognostics, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — Model-based machinery diagnostic and prognostic techniques depend upon high-quality mathematical models of the plant. Modeling uncertainties and errors decrease...

  10. Diagnostics for plasma control on DEMO: challenges of implementation

    NARCIS (Netherlands)

    Donne, A. J. H.; Costley, A. E.; Morris, A. W.

    2012-01-01

    As a test fusion power plant, DEMO will have to demonstrate reliability and very long pulse/steady-state operation, which calls for unprecedented robustness and reliability of all diagnostic systems (also requiring adequate redundancy). But DEMO will have higher levels of neutron and gamma fluxes,

  11. Non-Metropolitan Drinking Water Suppliers’ Response to the Diagnostic Tool for Non-Technical Compliance in Limpopo, South Africa

    Directory of Open Access Journals (Sweden)

    Avhashoni Dorcas Nefale

    2017-11-01

    Full Text Available Without the planning of non-technical issues, water treatment plants may face challenges in sustaining safe drinking water. Parameters such as the planning of financial resources, human resources, a lack of professional process controllers, poor working conditions, staff shortages and a lack of appropriate training of process controllers contribute to the underperformance of drinking water treatment plants. This study aimed at applying the Diagnostic Tool for Non-Technical Compliance to assess the compliance of small drinking water plants with management norms. Six water treatments (Vondo water scheme, Malamulele, Mutshedzi, Mutale regional water treatment plant, Tshedza and Tshedza package plant were selected from the Vhembe district municipality of the Limpopo province in South Africa. From the abovementioned non-technical parameters, the results showed that during the first assessment period (August 2008 and June 2009 selected water treatment plants scored between 53% and 68% and fell under Class 2, indicating serious challenges requiring attention and improvement. During the second assessment period (November and December 2010, a slight improvement was observed as all plants scored between 72% and 80%, falling under the Class 2 category. Even after corrective actions and remeasurement, none of the plants met the compliance standards, which range from 90% to 100% to obtain the Class 1 compliance standard. The study recommended that tactical and strategic plans that clearly define the operational procedures, process controlling, financial planning, maintenance culture, emergency preparedness and regular monitoring and evaluation should be entrenched for the smooth running of the small water treatment plants. Furthermore, all water services providers and water services authorities should apply the diagnostic tools as developed, which provides guidance on a stepwise procedure on plant operations and management on a daily basis.

  12. Gender incongruence: a comparative study using ICD-10 and DSM-5 diagnostic criteria.

    Science.gov (United States)

    Soll, Bianca M; Robles-García, Rebeca; Brandelli-Costa, Angelo; Mori, Daniel; Mueller, Andressa; Vaitses-Fontanari, Anna M; Cardoso-da-Silva, Dhiordan; Schwarz, Karine; Abel-Schneider, Maiko; Saadeh, Alexandre; Lobato, Maria-Inês-Rodrigues

    2018-01-01

    To compare the presence of criteria listed in the DSM-5 and ICD-10 diagnostic manuals in a Brazilian sample of transgender persons seeking health services specifically for physical transition. This multicenter cross-sectional study included a sample of 103 subjects who sought services for gender identity disorder in two main reference centers in Brazil. The method involved a structured interview encompassing the diagnostic criteria in the two manuals. The results revealed that despite theoretical disagreement about the criteria, the manuals overlap regarding diagnosis confirmation; the DSM-5 was more inclusive (97.1%) than the ICD-10 (93.2%) in this population. Although there is no consensus on diagnostic criteria on transgenderism in the diversity of social and cultural contexts, more comprehensive diagnostic criteria are evolving due to society's increasing inclusivity.

  13. Capabilities and diagnostics of the Sandia Pelletron-raster system

    International Nuclear Information System (INIS)

    Buckalew, W.H.; Lockwood, G.J.; Luker, S.M.; Ruggles, L.E.; Wyant, F.J.

    1984-07-01

    The radiation capabilities of the PELLETRON Electron Beam Accelerator have been expanded to include a controllable, variable dimension, beam diffusion option. This rastered beam option has been studied in detail. Beam characteristics have been determined as a function of incident electron beam energy, current, and deflection system parameters. The beam diagnostics required to define any given diffuse beam pattern are accurate and predictable. Recently, utility of this added PELLETRON capability was demonstrated by simulating the effects of complex nuclear reactor accident electron environments on electrical insulation materials similar to those used in nuclear power plants

  14. Gear noise, vibration, and diagnostic studies at NASA Lewis Research Center

    Science.gov (United States)

    Zakrajsek, J. J.; Oswald, F. B.; Townsend, D. P.; Coy, J. J.

    1990-01-01

    The NASA Lewis Research Center and the U.S. Army Aviation Systems Command are involved in a joint research program to advance the technology of rotorcraft transmissions. This program consists of analytical as well as experimental efforts to achieve the overall goals of reducing weight, noise, and vibration, while increasing life and reliability. Recent analytical activities are highlighted in the areas of gear noise, vibration, and diagnostics performed in-house and through NASA and U.S. Army sponsored grants and contracts. These activities include studies of gear tooth profiles to reduce transmission error and vibration as well as gear housing and rotordynamic modeling to reduce structural vibration and transmission and noise radiation, and basic research into current gear failure diagnostic methodologies. Results of these activities are presented along with an overview of near-term research plans in the gear noise, vibration, and diagnostics area.

  15. Empirical evidence of design-related bias in studies of diagnostic tests

    NARCIS (Netherlands)

    Lijmer, J. G.; Mol, B. W.; Heisterkamp, S.; Bonsel, G. J.; Prins, M. H.; van der Meulen, J. H.; Bossuyt, P. M.

    1999-01-01

    CONTEXT: The literature contains a large number of potential biases in the evaluation of diagnostic tests. Strict application of appropriate methodological criteria would invalidate the clinical application of most study results. OBJECTIVE: To empirically determine the quantitative effect of study

  16. Laser diagnodent: a comparative study with other diagnostic techniques

    International Nuclear Information System (INIS)

    Godinho, Reugma Rego

    2002-01-01

    An evaluation of the Diagnodent equipment (Kavo Company, Germany) for the occlusal caries detection was dane through the comparison with other conventional diagnostic techniques, such as visual inspection, intra-oral micro camera and digital X-ray. The effectiveness of the equipment in the detection of hidden caries and its viability as a diagnosis method for caries in their initial stage was also studied. Fifty eight permanent molars and premolars teeth from patients with age between 6 and 30 years were studied. The obtained results indicated that the conventional methods employed for the caries diagnosis are unable to detect the carious lesion in its initial stage. The Diagnodent equipment has this capability to detect caries presenting a flawless surface, specially the hidden caries, allowing the dentist to decide between a preventive ar a conservative procedure. The main advantage of the Diagnodent is to be an objective method, compared to the visual and radiographic ones, that are dependent on the professional interpretation. The Diagnodent is, therefore, a promising alternative as an objective and standardized diagnosis method for the final diagnostic. (author)

  17. Some methods of analysis and diagnostics of corroded components from nuclear power plant

    International Nuclear Information System (INIS)

    Mogosan, S.; Radulescu, M.; Fulger, M.; Stefanescu, D.

    2010-01-01

    In Nuclear Power Plants (NPP) it is necessary to ensure a longer and safe operation as difficult and expensive it is the maintenance of these very complex installations and equipment. In this regard, The Analysis and Diagnostic Laboratory Corroded Metal Components in Nuclear Facilities-LADICON; was authorized RENAR and CNCAN (National Commission for Nuclear Activities Control) notified as a testing laboratory for nuclear-grade materials. As part of the investigation and evaluation of corrosion behavior for these materials two types of test methods are used i.e. longer corrosion tests such as: autoclaving at high temperature and pressure in different chemical media-specific patterns in NPP and accelerated methods like: electrochemical techniques, accelerated chemical tests, etc. This paper presents some methods of analysis for materials corrosion; methods of assessment of corrosion of structural materials exposed to specific operating conditions and environment in NPPs. The electrochemical measurements show the following advantages: a) Allowing a direct method to accelerate the corrosion processes without altering the environment, b) It can be used as an nondestructive tool for assessing the rate of corrosion and c) Offers the possibility of conducting such investigations in - situ and ex- situ. Corroborating the environmental chemistry that was born on samples movies investigation results obtained by the methods above, it is possible to identify the types of corrosion of the materials and sometimes even those processes and mechanisms of corrosion. (authors)

  18. Diagnostic model for assessing traceability system performance in fish processing plants

    NARCIS (Netherlands)

    Mgonja, J.T.; Luning, P.A.; Vorst, van der J.G.A.J.

    2013-01-01

    This paper introduces a diagnostic tool that can be used by fish processing companies to evaluate their own traceability systems in a systematic manner. The paper begins with discussions on the rationale of traceability systems in food manufacturing companies, followed by a detailed analysis of the

  19. Recent computer applications in boiling water reactor power plants

    International Nuclear Information System (INIS)

    Hiraga, Shoji; Joge, Toshio; Kiyokawa, Kazuhiro; Kato, Kanji; Nigawara, Seiitsu

    1976-01-01

    Process computers in boiling water reactor power plants have won the position of important equipments for the calculation of the core and plant performances and for data logging. Their application technique is growing larger and larger every year. Here, two systems are introduced; plant diagnostic system and computerized control panel. The plant diagnostic system consists of the part processing the signals from a plant, the operation part mainly composed of a computer to diagnose the operating conditions of each system component using input signal, and the result display (CRT or typewriter). The concept on the indications on control panels in nuclear power plants is changing from ''Plant parameters and to be indicated on panel meters as much as possible'' to ''Only the data required for operation are to be indicated.'' Thus the computerized control panel is attracting attention, in which the process computer for processing the operating information and CRT display are introduced. The experimental model of that panel comprises and operator's console and a chief watchmen's console. Its functions are dialogic data access and the automatic selection of preferential information. (Wakatsuki, Y.)

  20. Development of A Plant Navigation System

    International Nuclear Information System (INIS)

    Furuta, Tomihiko; Nakagawa, Tsuneo; Kubota, Ryuji; Ikeda, Kouji

    1998-01-01

    A 'Plant Navigation System (PNS)' is under development to assist nuclear power plant (NPP) operators by automatically displaying the plant situation and plant operational procedures on a CRT screen when abnormalities occur. The operation procedures given in a symptom-oriented manual are expressed in a tree - type flowchart (modified PAD). The optimum operation procedure for an NPP is selected automatically using built-in diagnostic logics based on the current status of the NPP. Concerning the plant situation, the PNS displays important information only on the current status of the NPP. A prototype PNS system is being constructed. (authors)

  1. The study of practices in planed diagnostic medical exposure

    International Nuclear Information System (INIS)

    Popescu, Irina-Anca; Perju, Nicoleta Ana-Maria; Cobzeanu, Camelia

    2011-01-01

    The exposure of population to ionizing radiations in medical diagnostic purposes represents a planed exposure procedure, medically justified, having a direct impact on patient health state. A justification of exposure, with a result that can confirm a clinical diagnostic, implies further important steps in treatment decisions. Optimization in patients radiological protection is the result of observing the reference levels recommendations, which maintains a reasonable individual exposure to ionizing radiation in medical purpose. In this paper we investigated the justification of 4189 exposures of patients who underwent planed diagnostic medical investigation over 36 months in a radiological unit. The most frequent investigation concerned the spinal column in 38.3% of total exposures-mainly at lumbar level (63.0% and 24.1%, respectively of total number of exposures), followed by limb bones (20.6%) and thorax (26.9%). Justification of practices included: rheumatic pains in 45.8% of exposures followed by traumatic injuries (20.6%), pleural and pulmonary pathology (19.3%), malignant processes (12.3%), ear-nose-throat investigations (1.1%) and car accidents (0.9%). The females over 40 years old were the group with the highest number of medical exposures, with 54.5% of total practices. This study revealed that the number of medical exposures justification is almost equal with non-justified examinations, confirming a not so good correlation between clinical diagnostic and the required radiological investigation. The percentages of justified versus non-justified practices indicated by specialist physicians and general practitioners were slightly equal - 59.3% vs. 40.7%, 56.9% vs. 43.1%, respectively. The analysis of data concluded that either specialist/general physicians must evaluate more rigorously the patients and all clinical signs in order to reduce as reasonable as possible the non-justified medical exposures to ionizing radiations, and thus to avoid financial and

  2. Plant dynamics studies towards design of plant protection system for PFBR

    Energy Technology Data Exchange (ETDEWEB)

    Natesan, K., E-mail: natesan@igcar.gov.in [Nuclear and Safety Engineering Group, Indira Gandhi Centre for Atomic Research, Kalpakkam 603 102 (India); Kasinathan, N.; Velusamy, K.; Selvaraj, P.; Chellapandi, P. [Nuclear and Safety Engineering Group, Indira Gandhi Centre for Atomic Research, Kalpakkam 603 102 (India)

    2012-09-15

    Highlights: Black-Right-Pointing-Pointer Analysis of various design basis events in a fast breeder reactor towards design of plant protection system. Black-Right-Pointing-Pointer Plant dynamic modeling of a sodium cooled fast breeder reactor. Black-Right-Pointing-Pointer Selection of optimum set of plant parameters for considering best plant availability. - Abstract: Prototype fast breeder reactor (PFBR) is a 500 MWe (1250 MWt) liquid sodium cooled pool type reactor currently under construction in India. For a safe and efficient operation of the plant, it is necessary that the reactor is protected from all the transients that may occur in the plant. In order to accomplish this, adequate number of SCRAM parameters is required in the plant protection system with reliable instrumentation. For identifying the SCRAM parameters, the neutronic and thermal hydraulic responses of the plant for various possible events need to be established. Towards this, a one dimensional plant dynamics code DYANA-P has been developed with thermal hydraulic models for reactor core, hot and cold pools, intermediate heat exchangers, pipelines, steam generator, primary sodium circuits and secondary sodium circuits. The code also incorporates neutron kinetics and reactivity feedback models. By a comprehensive plant dynamics study an optimum list of SCRAM parameters and the maximum permissible response time for various instruments used for deriving them have been arrived at.

  3. A simulation-based expert system for nuclear power plant diagnostics

    International Nuclear Information System (INIS)

    Hassberger, J.A.; Lee, J.C.

    1989-01-01

    An expert system for diagnosing operational transients in a nuclear power plant is discussed. Hypothesis and test is used as the problem-solving strategy with hypotheses generated by an expert system that monitors the plant for patterns of data symptomatic of known failure modes. Fuzzy logic is employed as the inferencing mechanism with two complementary implication schemes to handle scenarios involving competing failures. Hypothesis testing is performed. An artificial intelligence framework based on a critical functions approach is used to deal with the complexity of a nuclear plant. A prototype system for diagnosing transients in the reactor coolant system of a pressurized water reactor has been developed to test the algorithms described here. Results are presented for the diagnosis of data from the Three Mile Island Unit 2 loss-of-feedwater/small-break loss-of-collant accident

  4. DIAGNOSTICS OF VIRUS PHYTOPATHOGENS FRUIT TREE PLUM POX VIRUS, PRUNUS NECROTIC RINGSPOT VIRUS AND PRUNUS DWARF VIRUS BY BIOLOGICAL AND MOLECULAR DIAGNOSTICS

    Directory of Open Access Journals (Sweden)

    Július Rozák

    2013-02-01

    Full Text Available The aim of this study was to determine the incidence of viral phytopathogen Plum pox virus, Prunus necrotic ringspot virus and Prunus dwarf virus in selected localities of Slovakia and diagnose them using a molecular and biological methods. Forty samples of fruit trees of the genus Prunus, twenty samples from intensive plantings and twenty samples from wild subject were analysed. Biological diagnostic by using biological indicators Prunus persica cv. GF 305, Prunus serrulata cv. Schirofugen and molecular diagnostic by mRT-PCR were applied. Five samples with Plum pox virus were infected. The two samples positive for Prunus necrotic ringspot virus and one sample for Prunus dwarf virus were confirmed. The two samples were found to be infected with two viruses Prunus necrotic ringspot virus and Prunus dwarf virus. This work focuses on two techniques, their application to the diagnosis of stone fruit viruses and their routinely used for sanitary and certification programmes.

  5. Operation and maintenance of nuclear power plant

    International Nuclear Information System (INIS)

    1990-04-01

    The proceedings contain 34 papers, almost all discussing specific problems or the Dukovany nuclear power plant. The major part is devoted to the matters of maintenance, regular and unplanned repairs, decontamination of the steam generator for inspection and repair purposes, various methods of in-service diagnostics. Some papers discuss reactor start-up, safety assurance, unit control and economic aspects. Environmental impacts of the power plant are also tackled. Some special contributions concern corrosion, chemical analysis of the coolant and the diagnostics of electrical equipment. The possibility is discussed of switching WWER reactors to improved fuel cycles with increased fuel burnup. (M.D.). 37 figs., 23 tabs., 47 refs

  6. Effects of radiation exposure from radiopharmaceuticals used in diagnostic studies

    International Nuclear Information System (INIS)

    Witcofski, R.L.

    1981-01-01

    In the United States about 90 percent of man-made radiation exposure to the general population is from the use of radiation in diagnostic medicine. Although the doses of radiation from these procedures to individuals are generally quite small, large numbers of people are exposed. Estimates of the radiation doses associated with such use in the healing arts are approximately 15 million person-rem to the general population from diagnostic x ray and 3.3 million person-rem from the diagnostic use of radiopharmaceuticals. The purpose of this paper is to present what is known about the possible effects of radiation from diagnostic radiopharmaceuticals

  7. Rational diagnostic studies of hyperthyroidism - can they be rationalized

    International Nuclear Information System (INIS)

    Schuemichen, C.; Bernhard, G.; Aurnhammer, R.

    1983-01-01

    The value of various diagnostic tests for recognizing hyperthyroidism was assessed in 285 patients. The prevalence of hyperthyroidism was 33% altogether: 21.8% diffuse hyperthyroidism (Graves' disease and disseminated autonomy) and 11.2% autonomous adenoma. A negative TRH-test was found in 29.5% of the euthyroid patients, 11.4% in patients younger and 40.7% in patients older than 50 years. In one patient with thyrotoxicosis the TRH-test was positive in the beginning. In 29% of the patients with diffuse hyperthyroidism and in 50% of the patients with hyperthyroid autonomous adenoma only one hormone level was elevated (T 3 , T 4 or FT 4 ). The radioioine test contributed primarily to the final diagnosis in 1.6% of diffuse hyperthyroidism and in 6.2% of hyperthyroid autonomous adenoma. Because of its high sensitivity the TRH-test remains the basic test in the diagnosis of thyrotoxicosis. The diagnostic value of T 3 and FT 4 is equivalent with slight advantages of FT 4 . In order to lower costs, the total T 4 measurements can, and the radioiodine test has to be, omitted. However, it ought to be kept in mind that if only the TRH test and T 3 and FT 4 are included in the diagnostic study, the final diagnosis is not substantiated adequately in one third of the patients with thyrotoxicosis. (orig.) [de

  8. Westinghouse ICF power plant study

    International Nuclear Information System (INIS)

    Sucov, E.W.

    1980-10-01

    In this study, two different electric power plants for the production of about 1000 MWe which were based on a CO 2 laser driver and on a heavy ion driver have been developed and analyzed. The purposes of this study were: (1) to examine in a self consistent way the technological and institutional problems that need to be confronted and solved in order to produce commercially competitive electricity in the 2020 time frame from an inertial fusion reactor, and (2) to compare, on a common basis, the consequences of using two different drivers to initiate the DT fuel pellet explosions. Analytic descriptions of size/performance/cost relationships for each of the subsystems comprising the power plant have been combined into an overall computer code which models the entire plant. This overall model has been used to conduct trade studies which examine the consequences of varying critical design values around the reference point

  9. The Impact of Diagnostic Code Misclassification on Optimizing the Experimental Design of Genetic Association Studies

    Directory of Open Access Journals (Sweden)

    Steven J. Schrodi

    2017-01-01

    Full Text Available Diagnostic codes within electronic health record systems can vary widely in accuracy. It has been noted that the number of instances of a particular diagnostic code monotonically increases with the accuracy of disease phenotype classification. As a growing number of health system databases become linked with genomic data, it is critically important to understand the effect of this misclassification on the power of genetic association studies. Here, I investigate the impact of this diagnostic code misclassification on the power of genetic association studies with the aim to better inform experimental designs using health informatics data. The trade-off between (i reduced misclassification rates from utilizing additional instances of a diagnostic code per individual and (ii the resulting smaller sample size is explored, and general rules are presented to improve experimental designs.

  10. Human anti-rhesus D IgG1 antibody produced in transgenic plants

    DEFF Research Database (Denmark)

    Bouquin, Thomas; Thomsen, Mads; Nielsen, Leif Kofoed

    2002-01-01

    antigen, which is responsible for alloimmunization of RhD- mothers carrying an RhD+ fetus. Anti-RhD extracted from plants specifically reacted with RhD+ cells in antiglobulin technique, and elicited a respiratory burst in human peripheral blood mononuclear cells. Plant-derived antibody had equivalent......Transgenic plants represent an alternative to cell culture systems for producing cheap and safe antibodies for diagnostic and therapeutic use. To evaluate the functional properties of a 'plantibody', we generated transgenic Arabidopsis plants expressing full-length human IgG1 against the Rhesus D...... properties to CHO cell-produced anti-RhD antibody, indicating its potential usefulness in diagnostic and therapeutic programs....

  11. Search strategies to identify diagnostic accuracy studies in MEDLINE and EMBASE

    NARCIS (Netherlands)

    Beynon, Rebecca; Leeflang, Mariska M. G.; McDonald, Steve; Eisinga, Anne; Mitchell, Ruth L.; Whiting, Penny; Glanville, Julie M.

    2013-01-01

    A systematic and extensive search for as many eligible studies as possible is essential in any systematic review. When searching for diagnostic test accuracy (DTA) studies in bibliographic databases, it is recommended that terms for disease (target condition) are combined with terms for the

  12. CSRL application to nuclear power plant diagnosis and sensor data validation

    International Nuclear Information System (INIS)

    Hashemi, S.; Punch, W.F. III; Hajek, B.K.

    1988-01-01

    During operational abnormalities, plant operators rely on the information provided by the plant sensors and associated alarms. The sensors' usefulness however, is quickly diminished by their large number and the extremely difficult task of interpreting and comprehending the provided information. Malfunction diagnosis can be further complicated by the existence of conflicting data which can lead to an incorrect diagnostic conclusion. Thus, the value of an operator aid to assist plant personnel in interpreting the available data and diagnosing the plant malfunctions is obvious. Recent work at the Ohio State University Laboratory for Artificial Intelligence Research (OSU-LAIR) and the Nuclear Engineering department has concentrated on the problem of performing expert system diagnosis using potentially invalid sensor data. That is, the authors have been developing expert systems that can perform diagnostic problem solving despite the existence of some conflicting data in the domain. This work has resulted in enhancement of a programming tool, CSRL, that allows domain experts to create a diagnostic system that will be, to some degree, tolerant of bad data. The domain of Boiling Water Nuclear Power Plants was chosen as a test domain to show usefulness of the ideas under real world conditions

  13. CSRL application to nuclear power plant diagnosis and sensor data validation

    International Nuclear Information System (INIS)

    Hashemi, S.; Punch, W.F. III; Hajek, B.K.

    1987-01-01

    During operational abnormalities, plant operators rely on the information provided by the plant sensors and associated alarms. The sensors' usefulness however, is quickly diminished by their large number and the extremely difficult task of interpreting and comprehending the provided information. Malfunction diagnosis can be further complicated by the existence of conflicting data which can lead to an incorrect diagnostic conclusion. Thus, the value of an operator aid to assist plant personnel in interpreting the available data and diagnosing the plant malfunctions is obvious. Recent work at the Ohio State University Laboratory for Artificial Intelligence Research (OSU-LAIR) and the Nuclear Engineering Department has concentrated on the problem of performing expert system diagnosis using potentially invalid sensor data. Expert systems have been developed that can perform diagnostic problem solving despite the existence of some conflicting data in the domain. This work has resulted in enhancement of a programming tool, CSRL, that allows domain experts to create a diagnostic system that will be, to some degree, tolerant of bad data. The domain of Boiling Water Nuclear Power Plants was chosen as a test domain to show usefulness of the ideas under real world conditions

  14. Advanced liquid metal reactor plant control system

    International Nuclear Information System (INIS)

    Dayal, Y.; Wagner, W.; Zizzo, D.; Carroll, D.

    1993-01-01

    The modular Advanced Liquid Metal Reactor (ALMR) power plant is controlled by an advanced state-of-the-art control system designed to facilitate plant operation, optimize availability, and protect plant investment. The control system features a high degree of automatic control and extensive amount of on-line diagnostics and operator aids. It can be built with today's control technology, and has the flexibility of adding new features that benefit plant operation and reduce O ampersand M costs as the technology matures

  15. 75 FR 52505 - Fiscal Year 2011 Veterinary Import/Export Services, Veterinary Diagnostic Services, and Export...

    Science.gov (United States)

    2010-08-26

    ... plant and plant product export certification program operations, contact Mr. William E. Thomas, Director...; Birds or poultry, including zoo birds or poultry, receiving nonstandard housing, care, or handling to... diseases of livestock and poultry within the United States. Veterinary diagnostics is the work performed in...

  16. Expert system for nuclear power plant feedwater system diagnosis

    International Nuclear Information System (INIS)

    Meguro, R.; Kinoshita, Y.; Sato, T.; Yokota, Y.; Yokota, M.

    1987-01-01

    The Expert System for Nuclear Power Plant Feedwater System Diagnosis has been developed to assist maintenance engineers in nuclear power plants. This system adopts the latest process computer TOSBAC G8050 and the expert system developing tool TDES2, and has a large scale knowledge base which consists of the expert knowledge and experience of engineers in many fields. The man-machine system, which has been developed exclusively for diagnosis, improves the man-machine interface and realizes the graphic displays of diagnostic process and path, stores diagnostic results and searches past reference

  17. Diagnostics for a coal-fired MHD retrofit of an existing power station

    Energy Technology Data Exchange (ETDEWEB)

    Cook, R L; Shepard, W S [Mississippi State Univ. (USA). Diagnostic Instrumentation and Analysis Lab.

    1990-01-01

    MHD flows represent one of the most severe environments encountered by gasdynamic diagnostics. Special state-of-the-art techniques and instrumentation systems are required to monitor and collect data for the MHD components, and these diagnostic systems must operate under very severe environmental and magnetic field conditions. The Diagnostic Instrumentation and Analysis Laboratory (DIAL) at Mississippi State University has developed, and is continuing to develop, advanced optical diagnostic techniques and instrumentation systems to provide nonintrusive, remote real-time measurements and to operate successfully in the industrial-like environment of a large-scale MHD retrofit power station. Such diagnostic instrumentation can provide the information to completely evaluate the performance of individual components, as well as, the entire power plant. It is essential to determine as much detail as possible about the various component operations in an MHD retrofit system so that a commercial plant design can be optimized quickly. This paper discusses the instrumentation systems which DIAL proposed for an MHD retrofit of an existing power station. Instruments which have been making measurements on the U.S. MHD test facilities for several years are presented, along with instruments which will be available within two years. Parameters to be measured along with location and frequency are discussed in detail. These parameters include electron density, electrical conductivity, K-atom density, gas temperature, gas velocity, temperature and velocity profiles, gas composition, and particle size, number, density and distrib00000

  18. In-operation diagnostic system for reactor coolant pump

    International Nuclear Information System (INIS)

    Sugiyama, Mitsunobu; Hasegawa, Ichiro; Kitahara, Hiromichi; Shimamura, Kazuo; Yasuda, Chiaki; Ikeda, Yasuhiro; Kida, Yasuo.

    1996-01-01

    A reactor coolant pump (RCP) is one of the most important rotating machines in the primary loop nuclear power plants. To improve the reliability and of nuclear power plants, a new diagnostic system that enables early detection of RCP faults has been developed. This system is based on continuous monitoring of vibration and other process data. Vibration is an important indicator of mechanical faults providing information on physical phenomena such as changes in dynamic characteristics and excitation forces changes that signal failure or incipient failure. This new system features comparative vibration analysis and simulation to anticipate equipment failure. (author)

  19. Diagnostic and monitoring systems in nuclear power plants

    International Nuclear Information System (INIS)

    Wehling, H.J.; Jax, P.; Streicher, V.

    1987-01-01

    Monitoring systems are important for the availability of nuclear power plants. A survey is given about such systems designed and constructed by the Kraftwerk Union AG Erlangen (Federal Republic of Germany) in order to assure the mechanical integrity of reactor cooling systems. Three monitoring systems based on microprocessors are presented: KUES (acoustic detection of loose parts), SUES (vibration), and FAMOS (fatigue)

  20. Reactor noise diagnostics based on multivariate autoregressive modeling: Application to LOFT [Loss-of-Fluid-Test] reactor process noise

    International Nuclear Information System (INIS)

    Gloeckler, O.; Upadhyaya, B.R.

    1987-01-01

    Multivariate noise analysis of power reactor operating signals is useful for plant diagnostics, for isolating process and sensor anomalies, and for automated plant monitoring. In order to develop a reliable procedure, the previously established techniques for empirical modeling of fluctuation signals in power reactors have been improved. Application of the complete algorithm to operational data from the Loss-of-Fluid-Test (LOFT) Reactor showed that earlier conjectures (based on physical modeling) regarding the perturbation sources in a Pressurized Water Reactor (PWR) affecting coolant temperature and neutron power fluctuations can be systematically explained. This advanced methodology has important implication regarding plant diagnostics, and system or sensor anomaly isolation. 6 refs., 24 figs

  1. A hybrid model for combining case-control and cohort studies in systematic reviews of diagnostic tests

    Science.gov (United States)

    Chen, Yong; Liu, Yulun; Ning, Jing; Cormier, Janice; Chu, Haitao

    2014-01-01

    Systematic reviews of diagnostic tests often involve a mixture of case-control and cohort studies. The standard methods for evaluating diagnostic accuracy only focus on sensitivity and specificity and ignore the information on disease prevalence contained in cohort studies. Consequently, such methods cannot provide estimates of measures related to disease prevalence, such as population averaged or overall positive and negative predictive values, which reflect the clinical utility of a diagnostic test. In this paper, we propose a hybrid approach that jointly models the disease prevalence along with the diagnostic test sensitivity and specificity in cohort studies, and the sensitivity and specificity in case-control studies. In order to overcome the potential computational difficulties in the standard full likelihood inference of the proposed hybrid model, we propose an alternative inference procedure based on the composite likelihood. Such composite likelihood based inference does not suffer computational problems and maintains high relative efficiency. In addition, it is more robust to model mis-specifications compared to the standard full likelihood inference. We apply our approach to a review of the performance of contemporary diagnostic imaging modalities for detecting metastases in patients with melanoma. PMID:25897179

  2. Agreement between Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, and the proposed DSM-V attention deficit hyperactivity disorder diagnostic criteria: an exploratory study.

    Science.gov (United States)

    Ghanizadeh, Ahmad

    2013-01-01

    There is no empirical literature about the American Psychiatry Association proposed new diagnostic criteria for attention deficit hyperactivity disorder (ADHD). This study examined the agreement between ADHD diagnosis derived from Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV), and DSM-V diagnostic criteria. It also reports sensitivity, specificity, and agreement for ADHD diagnosis. A clinical sample of 246 children and adolescents were interviewed face to face using both ADHD diagnostic criteria for DSM-V and DSM-IV by interviewing clinician. Comorbid psychiatric disorders were screened using DSM-IV criteria. The rate of ADHD diagnosis using DSM-V was significantly higher than the rate detected by using DSM-IV diagnostic criteria. The sensitivity of DSM-V diagnostic criteria was 100%, while its specificity was 71.1%. The kappa agreement between DSM-IV and DSM-V was 0.75. In addition, positive predictive value was 85.1%. All the four newly added symptoms to ADHD diagnostic criteria are statistically more common in the children with ADHD than those in the comparison group. However, these symptoms are also very common in the children without ADHD. It is expected that the rate of ADHD would increase using the proposed ADHD DSM-V criteria. Moreover, the newly added symptoms have a low specificity for ADHD diagnosis. Copyright © 2013 Elsevier Inc. All rights reserved.

  3. Failure diagnostics of rotational machines and machine groups in the Paks Nuclear Power Plant

    International Nuclear Information System (INIS)

    Nagy, I.; Kiss, G.

    1997-01-01

    Machine failure diagnostic system based on vibration analysis is described. The design of the measurements, the measurement procedure, and the evaluation of the results are presented. The common diagnostic technology for groups of rotation machinery has several advantages. The rules used for the evaluation of three-directional vibration measurements are shown, and the identification criteria of some specific failures are demonstrated. The steps of expert decision making and the diagnosis procedure are discussed through practical examples. (R.P.)

  4. Identification and diagnostic evaluation of possible dementia in general practice. A prospective study

    DEFF Research Database (Denmark)

    Waldorff, Frans Boch; Rishøj, Susanne; Waldemar, Gunhild

    2005-01-01

    , and 4 (3%) were treated for depression or referred for another condition. A total of 6 patients were lost to follow-up. In the remaining 102 undiagnosed patients the main reasons for not performing a diagnostic evaluation of dementia were patient/relative hesitation (34%), the GP thought that it would......OBJECTIVE: To investigate the rate of diagnostic evaluation of dementia for patients in whom a suspicion of dementia was raised, and to investigate reasons why a diagnostic evaluation was not always being performed. DESIGN: A prospective study among elderly patients aged 65+, and a follow-up study...... of dementia, laboratory-screening tests prescribed by the GPs and referral status after 6 months, and follow-up questionnaire. RESULTS: Of 793 patients a total of 138 patients were identified with possible dementia. Among the identified patients 26 (20%) were referred for further evaluation within 6 months...

  5. A study on the applications of expert systems and neural networks for the development of operator support systems in nuclear power plants

    International Nuclear Information System (INIS)

    Cheon, Se Woo

    1993-02-01

    In order to assist operators in effectively maintaining plant safety and to enhance plant availability, the need to develop operator support systems is growing to increase. The application of both expert system and neural network technologies to the operator support has the potential to increase the performance of these systems. A prototype integrated operator support system, called NSSS-DS, has been developed for multiple alarm processing, plant trip diagnosis, and the failure diagnosis of three main systems (a rod control system, reactor coolant pumps (RCPs) and a pressurizer) in the primary side of the Kori-2 nuclear power plant. This system diagnoses system malfunction quickly and offers appropriate guidance to operators. The system uses rule-based deduction with certainty factor operation. Diagnosis is performed using an establish-refine inference strategy. This strategy is to match a set of symptoms with a specific malfunction hypothesis in a predetermined structure of possible hypotheses. The diagnostic symptoms include alarms, indication lamps, parameter values and valve lineup that can be acquired at a main control room. The overall plant-wide diagnosis is performed at the main control part which can process multiple alarms and diagnose possible failure modes and failed systems in the plant. The method of alarm processing is the object-oriented approach in which each alarm can be represented as an active data element, an object. The alarm processing is performed using alarm processing meta rules and alarm processing frames. Also, the diagnosis of a plant trip can be performed at the main control part. The specific diagnosis of the three main systems can be performed followed by the diagnostic results of the main control part. The system also provides follow-up treatments to the operators. The application to these systems is described from the point of view of diagnostic strategies. For the applications of the neural network technology, two feasibility

  6. General review of diagnostic systems in EDF PWR units

    International Nuclear Information System (INIS)

    Chevalier, R.; Brasseur, S.; Ricard, B.

    1998-01-01

    Since the beginning of the French nuclear program, Electricite de France (EDF) has looked for ways to improve the availability and safety of its nuclear units. Therefore, monitoring systems on turbogenerators, reactor coolant pumps, primary circuits and core internal structures were designed by the Research and Development Division and implemented with technologies available during the 1970's. However, mainly because of difficulties for data interpretation by plant personnel, EDF subsequently decided to design and develop different tools to help plant operators to process a diagnosis: - a new generation of the Monitoring and Diagnostic System called PSAD, - expert systems for diagnosis on reactor coolant pumps (RCP) 'DIAPO' and turbogenerator units (TG) 'DIVA', - diagnostic guides written for most equipment pending the installation of new monitoring and diagnosis systems. The first version of PSAD, installed in five units, performs on-line monitoring of the turbogenerator shaft line, steam inlet valves, the reactor coolant pumps and the generator stator. The second version not yet implemented, will include Loose Part Detection (LPD) and Core Internal Structure Monitoring (CISM). The level of diagnosis achieved by PSAD depends on the component monitored. The TG and RCP monitoring functions of PSAD compute high level diagnosis descriptors such as natural frequencies and long term trends but do not elaborate a diagnosis automatically. However, a diagnostic assistance window is available on-line, whenever a warning message is displayed, whether for immediate or later action. The window presents a diagnostic approach whose purpose is to find the causes of the symptoms observed. This diagnosis approach is automated in the DIVA and DIAPO expert systems. Numerous potential faults can be identified for both systems thanks to a hierarchy of abnormal situations. The user interactively answers questions when information is needed to progress in the diagnosis. The resulting

  7. Feasibility and cost efficiency of a diagnostic guideline for chronic polyneuropathy : a prospective implementation study

    NARCIS (Netherlands)

    Vrancken, A.F.J.E.; Kalmijn, S.; Buskens, E.; Franssen, H.; Wokke, J.H.J.; Notermans, N.C.

    2006-01-01

    Background: Extensive investigations are often performed to reveal the cause of chronic polyneuropathy. It is not known whether a restrictive diagnostic guideline improves cost efficiency without loss of diagnostic reliability. Methods: In a prospective multicentre study, a comparison was made

  8. The German risk study for nuclear power plants

    International Nuclear Information System (INIS)

    Birkhofer, A.

    1980-01-01

    In August 1979 results of the ''German Risk Study for Nuclear Power Plants'' were published. The Main Report, in which approach and results of the study are documented, has been available since the end of 1979. It was the charter of the study - which was performed on behalf of the Minister of Research and Technology of the Federal Republic of Germany - to apply as far as possible the methods of the US Reactor Safety Study (WASH-1400) to German plant and site conditions. A direct transfer of the results was not deemed justified, mainly for the following reasons: There is quite a number of differences between the design of the reference plants of WASH-1400 (Surry-1, Peach Bottom-2) and German nuclear power plants. The mean population density in the Federal Republic of Germany is more than ten times of the United States. In the vicinity of nuclear power plants the ratio is about 3:1. To calculate the collective risk resulting from reactor accidents, a total of 25 plants at 19 different sites in the Federal Republic of Germany were considered. This included all plants with 600 MW or more electrical output, which were in operation, under construction or in licensing process by July 1, 1977. As an approximation to the real situation, it has been assumed that all 25 plants are technically identical to the reference plant

  9. Evaluating radiographers' diagnostic accuracy in screen-reading mammograms: what constitutes a quality study?

    International Nuclear Information System (INIS)

    Debono, Josephine C; Poulos, Ann E

    2015-01-01

    The aim of this study was to first evaluate the quality of studies investigating the diagnostic accuracy of radiographers as mammogram screen-readers and then to develop an adapted tool for determining the quality of screen-reading studies. A literature search was used to identify relevant studies and a quality evaluation tool constructed by combining the criteria for quality of Whiting, Rutjes, Dinnes et al. and Brealey and Westwood. This constructed tool was then applied to the studies and subsequently adapted specifically for use in evaluating quality in studies investigating diagnostic accuracy of screen-readers. Eleven studies were identified and the constructed tool applied to evaluate quality. This evaluation resulted in the identification of quality issues with the studies such as potential for bias, applicability of results, study conduct, reporting of the study and observer characteristics. An assessment of the applicability and relevance of the tool for this area of research resulted in adaptations to the criteria and the development of a tool specifically for evaluating diagnostic accuracy in screen-reading. This tool, with further refinement and rigorous validation can make a significant contribution to promoting well-designed studies in this important area of research and practice

  10. Studying the effects of operators' problem solving behaviour when using a diagnostic expert system developed for the nuclear industry

    International Nuclear Information System (INIS)

    Holmstroem, C.B.O.; Volden, F.S.; Endestad, T.

    1992-01-01

    This paper describes an experiment with the purpose to also illustrate and discuss some of the methodological problems when empirically studying problem solving. The experiment which was the second in a series, conducted at the OECD Halden Reactor Project, aimed to assess the effect on nuclear power plant operators diagnostic behaviour when using a rule-based diagnostic expert system. The rule-based expert system used in the experiment is called DISKET (Diagnosis System Using Knowledge Engineering Technique) and was originally developed by the Japan Atomic Energy Research Institute (JAERI). The experiment was performed in the Halden man-machine laboratory using a full scope pressurized water reactor simulator. Existing data collection methods and experimental design principles includes possibilities but also limitations. This is discussed and experiences are presented. Operator performance in terms of quality of diagnosis is improved by the use of DISKET. The use of the DISKET system also influences operators problem solving behaviour. The main difference between the two experimental conditions can be characterized as while the DISKET users during the diagnosis process are following a strategy which is direct and narrowed, the non-DISKET users are using a much broader and less focused search when trying to diagnose a disturbance. (author)

  11. Liver biopsy as diagnostic method for poisoning by swainsonine-containing plants

    Science.gov (United States)

    With the aim to investigate the use of hepatic biopsies for the diagnosis of poisoning by swainsonine-containing plants, dry leaves of Ipomoea marcellia containing 0.02% of swainsonine were administered to goats. Group I, with six goats, ingested 4g/kg of dry plant (0.8mg of swainsonina/kg) until th...

  12. Feasibility and cost efficiency of a diagnostic guideline for chronic polyneuropathy: a prospective implementation study

    NARCIS (Netherlands)

    Vrancken, A. F. J. E.; Kalmijn, S.; Buskens, E.; Franssen, H.; Vermeulen, M.; Wokke, J. H. J.; Notermans, N. C.

    2006-01-01

    Extensive investigations are often performed to reveal the cause of chronic polyneuropathy. It is not known whether a restrictive diagnostic guideline improves cost efficiency without loss of diagnostic reliability. In a prospective multicentre study, a comparison was made between the workup in

  13. Computer-based diagnostic monitoring to enhance the human-machine interface of complex processes

    International Nuclear Information System (INIS)

    Kim, I.S.

    1992-02-01

    There is a growing interest in introducing an automated, on-line, diagnostic monitoring function into the human-machine interfaces (HMIs) or control rooms of complex process plants. The design of such a system should be properly integrated with other HMI systems in the control room, such as the alarms system or the Safety Parameter Display System (SPDS). This paper provides a conceptual foundation for the development of a Plant-wide Diagnostic Monitoring System (PDMS), along with functional requirements for the system and other advanced HMI systems. Insights are presented into the design of an efficient and robust PDMS, which were gained from a critical review of various methodologies developed in the nuclear power industry, the chemical process industry, and the space technological community

  14. XML Diagnostics Description Standard

    International Nuclear Information System (INIS)

    Neto, A.; Fernandes, H.; Varandas, C.; Lister, J.; Yonekawa, I.

    2006-01-01

    A standard for the self-description of fusion plasma diagnostics will be presented, based on the Extensible Markup Language (XML). The motivation is to maintain and organise the information on all the components of a laboratory experiment, from the hardware to the access security, to save time and money when problems arises. Since there is no existing standard to organise this kind of information, every Association stores and organises each experiment in different ways. This can lead to severe problems when the organisation schema is poorly documented or written in national languages. The exchange of scientists, researchers and engineers between laboratories is a common practice nowadays. Sometimes they have to install new diagnostics or to update existing ones and frequently they lose a great deal of time trying to understand the currently installed system. The most common problems are: no documentation available; the person who understands it has left; documentation written in the national language. Standardisation is the key to solving all the problems mentioned. From the commercial information on the diagnostic (component supplier; component price) to the hardware description (component specifications; drawings) to the operation of the equipment (finite state machines) through change control (who changed what and when) and internationalisation (information at least in the native language and in English), a common XML schema will be proposed. This paper will also discuss an extension of these ideas to the self-description of ITER plant systems, since the problems will be identical. (author)

  15. An empirical operationalization study of DSM-IV diagnostic criteria for premature ejaculation

    NARCIS (Netherlands)

    Waldinger, M. D.; Hengeveld, M. W.; Zwinderman, A. H.; Olivier, B.

    1998-01-01

    The DSM-IV diagnostic criteria for premature ejaculation remain to be investigated by a clinical study. A prospective study was therefore conducted to investigate the DSM-IV definition and to provide an empirical operationalization of premature ejaculation. In this study 140 men suffering from

  16. Experiments on data presentation to process operators in diagnostic tasks

    DEFF Research Database (Denmark)

    Rasmussen, Jens; Goodstein, L. P.

    1972-01-01

    Safety and reliability considerations in modern power plants have prompted our interest in man as an information receiver - especially in diagnostic tasks where the growing complexity of process plants and hence the amount of data involved make it imperative to give the staff proper support....... The great flexibility and capacity of the process computer for data reduction and presentation and for storing information on plant structure and functions give the system designer great freedom in the layout of information display for the staff, but the problem for the designer is how to make proper use...... of this freedom to support the operators efficiently. This is especially important in connection with unique, high-risk, and generally improbable abnormalities in plant functioning. Operator tasks and mental models and the need for matching the encoded information about the plant to these models are treated...

  17. Power plant conceptual studies in Europe

    International Nuclear Information System (INIS)

    Maisonnier, D.; Campbell, D.; Cook, I.; Pace, L. Di; Giancarli, L.; Hayward, J.; Puma, A. Li; Medrano, M.; Norajitra, P.; Roccella, M.; Sardain, P.; Tran, M.Q.; Ward, D.

    2007-01-01

    The European fusion programme is 'reactor oriented' and it is aimed at the successive demonstration of the scientific, the technological and the economic feasibility of fusion power. The European Power Plant Conceptual Study (PPCS) has been a study of conceptual designs of five commercial fusion power plants and the main emphasis was on system integration. It focused on five power plant models which are illustrative of a wider spectrum of possibilities. They are all based on the tokamak concept and they have approximately the same net electrical power output, 1500 MWe. These span a range from relatively near-term, based on limited technology and plasma physics extrapolations, to an advanced conception. The PPCS allows one to clarify the concept of DEMO, the device that will bridge the gap between ITER and the first-of-a-kind fusion power plant. An assessment of the PPCS models with limited extrapolations highlighted a number of issues that must be addressed to establish the DEMO physics and technological basis

  18. Pinellas Plant feasibility study. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-09-01

    The Pinellas Plant was built in 1956 to manufacture neutron generators, a principal component in nuclear weapons. In September 1990, the Department of Health and Rehabilitative Services (HRS) entered into an agreement with DOE to independently examine environmental monitoring data from the plant and health data from Pinellas County to determine if an epidemiological study is technically feasible to measure possible off-site health effects from ionizing radiation. Through normal plant operations, some radioactive materials have been released to the environment. Eighty percent of the total plant releases of 107,707 curies occurred in the early years of plant operation (1957--1960). The primary materials released were tritium gas, tritium oxide and krypton-85. Environmental monitoring for radioactive releases from the plant has been done regularly since 1975. The US Public Health Service Centers for Disease Control and Prevention (CDC), in assisting HRS, has determined that sufficient radiological data exist by which a dose reconstruction can be done. A dose reconstruction can provide an estimate of how much radiological exposure someone living in the vicinity of the Pinellas Plant may have suffered from environmental releases.

  19. Pinellas Plant feasibility study. Final report

    International Nuclear Information System (INIS)

    1994-09-01

    The Pinellas Plant was built in 1956 to manufacture neutron generators, a principal component in nuclear weapons. In September 1990, the Department of Health and Rehabilitative Services (HRS) entered into an agreement with DOE to independently examine environmental monitoring data from the plant and health data from Pinellas County to determine if an epidemiological study is technically feasible to measure possible off-site health effects from ionizing radiation. Through normal plant operations, some radioactive materials have been released to the environment. Eighty percent of the total plant releases of 107,707 curies occurred in the early years of plant operation (1957--1960). The primary materials released were tritium gas, tritium oxide and krypton-85. Environmental monitoring for radioactive releases from the plant has been done regularly since 1975. The US Public Health Service Centers for Disease Control and Prevention (CDC), in assisting HRS, has determined that sufficient radiological data exist by which a dose reconstruction can be done. A dose reconstruction can provide an estimate of how much radiological exposure someone living in the vicinity of the Pinellas Plant may have suffered from environmental releases

  20. The role of general practice in routes to diagnosis of lung cancer in Denmark: a population-based study of general practice involvement, diagnostic activity and diagnostic intervals.

    Science.gov (United States)

    Guldbrandt, Louise Mahncke; Fenger-Grøn, Morten; Rasmussen, Torben Riis; Jensen, Henry; Vedsted, Peter

    2015-01-22

    Lung cancer stage at diagnosis predicts possible curative treatment. In Denmark and the UK, lung cancer patients have lower survival rates than citizens in most other European countries, which may partly be explained by a comparatively longer diagnostic interval in these two countries. In Denmark, a pathway was introduced in 2008 allowing general practitioners (GPs) to refer patients suspected of having lung cancer directly to fast-track diagnostics. However, symptom presentation of lung cancer in general practice is known to be diverse and complex, and systematic knowledge of the routes to diagnosis is needed to enable earlier lung cancer diagnosis in Denmark. This study aims to describe the routes to diagnosis, the diagnostic activity preceding diagnosis and the diagnostic intervals for lung cancer in the Danish setting. We conducted a national registry-based cohort study on 971 consecutive incident lung cancer patients in 2010 using data from national registries and GP questionnaires. GPs were involved in 68.3% of cancer patients' diagnostic pathways, and 27.4% of lung cancer patients were referred from the GP to fast-track diagnostic work-up. A minimum of one X-ray was performed in 85.6% of all cases before diagnosis. Patients referred through a fast-track route more often had diagnostic X-rays (66.0%) than patients who did not go through fast-track (49.4%). Overall, 33.6% of all patients had two or more X-rays performed during the 90 days before diagnosis. Patients whose symptoms were interpreted as non-alarm symptoms or who were not referred to fast-track were more likely to experience a long diagnostic interval than patients whose symptoms were interpreted as alarm symptoms or who were referred to fast-track. Lung cancer patients followed several diagnostic pathways. The existing fast-track pathway must be supplemented to ensure earlier detection of lung cancer. The high incidence of multiple X-rays warrants a continued effort to develop more accurate lung

  1. Studies of neutron measurement methods for fusion plasma diagnostics

    International Nuclear Information System (INIS)

    Beimer, K.H.

    1986-03-01

    This thesis comprises several studies mainly devoted to neutron measurement systems for plasma diagnostics at JET (Joint European Torus). An in situ calibration of the U-235 fission chamber detectors located at JET is presented. These detectors are used for measuring the neutron yield from the thermonuclear reactions in the plasma. The energy spectrum of the neutrons from the reactions D(d,n) 3 He has been studied by means of a 3 He spectrometer. Especially, it was found that by measuring the width of the full energy peak in the response spectrum of the 3 He-spectrometer, the deuterium distribution in the deuterium targets used can be estimated. In order to measure different neutron energies it is necessary to obtain a detailed knowledge of the response of the spectrometer. Therefore, the response function to monoenergetic neutrons in the energy range 130-3030 keV was experimentally determined. Some work has been related to a design study of a 14 MeV spectrometer for neutron diagnostics. It is a combined proton-recoil and time-of-flight spectrometer for high resolution measurements. The main parts of it are the collimator, the scattering foil, and the detectors for the recoil protons and the scattered neutrons. The influence of proton straggling in the foil on the resolution and efficiency of the spectrometer has been studied. Furthermore, a three dimensional Monte Carlo code has been written and used for the design of the collimator. (author)

  2. Consensus-based reporting standards for diagnostic test accuracy studies for paratuberculosis in ruminants

    DEFF Research Database (Denmark)

    Gardner, Ian A.; Nielsen, Søren Saxmose; Whittington, Richard

    2011-01-01

    The Standards for Reporting of Diagnostic Accuracy (STARD) statement (www.stard-statement.org) was developed to encourage complete and transparent reporting of key elements of test accuracy studies in human medicine. The statement was motivated by widespread evidence of bias in test accuracy...... studies and the finding that incomplete or absent reporting of items in the STARD checklist was associated with overly optimistic estimates of test performance characteristics. Although STARD principles apply broadly, specific guidelines do not exist to account for unique considerations in livestock...... for Reporting of Animal Diagnostic Accuracy Studies for paratuberculosis), should facilitate improved quality of reporting of the design, conduct and results of paratuberculosis test accuracy studies which were identified as “poor” in a review published in 2008 in Veterinary Microbiology...

  3. Diagnostics

    DEFF Research Database (Denmark)

    Donné, A.J.H.; Costley, A.E.; Barnsley, R.

    2007-01-01

    of the measurements—time and spatial resolutions, etc—will in some cases be more stringent. Many of the measurements will be used in the real time control of the plasma driving a requirement for very high reliability in the systems (diagnostics) that provide the measurements. The implementation of diagnostic systems...... on ITER is a substantial challenge. Because of the harsh environment (high levels of neutron and gamma fluxes, neutron heating, particle bombardment) diagnostic system selection and design has to cope with a range of phenomena not previously encountered in diagnostic design. Extensive design and R......&D is needed to prepare the systems. In some cases the environmental difficulties are so severe that new diagnostic techniques are required. The starting point in the development of diagnostics for ITER is to define the measurement requirements and develop their justification. It is necessary to include all...

  4. DNA barcoding of invasive plants in China: A resource for identifying invasive plants.

    Science.gov (United States)

    Xu, Song-Zhi; Li, Zhen-Yu; Jin, Xiao-Hua

    2018-01-01

    Invasive plants have aroused attention globally for causing ecological damage and having a negative impact on the economy and human health. However, it can be extremely challenging to rapidly and accurately identify invasive plants based on morphology because they are an assemblage of many different families and many plant materials lack sufficient diagnostic characteristics during border inspections. It is therefore urgent to evaluate candidate loci and build a reliable genetic library to prevent invasive plants from entering China. In this study, five common single markers (ITS, ITS2, matK, rbcL and trnH-psbA) were evaluated using 634 species (including 469 invasive plant species in China, 10 new records to China, 16 potentially invasive plant species around the world but not introduced into China yet and 139 plant species native to China) based on three different methods. Our results indicated that ITS2 displayed largest intra- and interspecific divergence (1.72% and 91.46%). Based on NJ tree method, ITS2, ITS, matK, rbcL and trnH-psbA provided 76.84%, 76.5%, 63.21%, 52.86% and 50.68% discrimination rates, respectively. The combination of ITS + matK performed best and provided 91.03% discriminatory power, followed by ITS2 + matK (85.78%). For identifying unknown individuals, ITS + matK had 100% correct identification rate based on our database, followed by ITS/ITS2 (both 93.33%) and ITS2 + matK (91.67%). Thus, we propose ITS/ITS2 + matK as the most suitable barcode for invasive plants in China. This study also demonstrated that DNA barcoding is an efficient tool for identifying invasive species. © 2017 John Wiley & Sons Ltd.

  5. Ethnobotanic study of medicinal plants in Urmia city: identification and traditional using of antiparasites plants

    Directory of Open Access Journals (Sweden)

    Mahmoud Bahmani

    2014-09-01

    Full Text Available Objective: To identify the native medicinal plants used in parasitic diseases treatment in Urmia. Methods: This study was conducted among 35 Urmia herbalists to identify medicinal plants used in parasitic diseases treatment. We used direct observation and interviews with collected herbarium specimens by native herbs commonly in the treatment of parasitic diseases. Questionnaires were included apothecary personal information and native plants list with information includes plant local name, plant parts used, method of their use and traditional therapies. Herbarium samples listed in the questionnaire collected from the area and were sent to agricultural research centers and Urmia University Faculty of Agriculture for genus and species determination. Results: Thirteen medicinal plants from six families for treatment of diabetes in Urmia were obtained from interviews. Most families have anti diabetic effect was included Asteraceae (36%. The most used was boiling (65%. Conclusions: In view of the findings of this study indicate that plants have the potential to be a parasitic infection so it is necessary ingredients of native plants be studied to demonstrate therapeutic effects and provide field work to evaluate the clinical effects of these herbs and ingredients they claim on parasitic diseases.

  6. Diagnostic accuracy of temporomandibular disorder pain tests: a multicenter study

    NARCIS (Netherlands)

    Visscher, C.M.; Naeije, M.; de Laat, A.; Michelotti, A.; Nilner, M.; Craane, B.; Ekberg, E.; Farella, M.; Lobbezoo, F.

    2009-01-01

    AIMS: To estimate the diagnostic accuracy of the Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD) clinical examination and of the dynamic/static tests for the recognition of TMD pain. Since the diagnosis of TMD pain is especially complicated in persistent orofacial pain

  7. [Critical reading of articles about diagnostic tests (part I): Are the results of the study valid?].

    Science.gov (United States)

    Arana, E

    2015-01-01

    In the era of evidence-based medicine, one of the most important skills a radiologist should have is the ability to analyze the diagnostic literature critically. This tutorial aims to present guidelines for determining whether primary diagnostic articles are valid for clinical practice. The following elements should be evaluated: whether the study can be applied to clinical practice, whether the technique was compared to the reference test, whether an appropriate spectrum of patients was included, whether expectation bias and verification bias were limited, the reproducibility of the study, the practical consequences of the study, the confidence intervals for the parameters analyzed, the normal range for continuous variables, and the placement of the test in the context of other diagnostic tests. We use elementary practical examples to illustrate how to select and interpret the literature on diagnostic imaging and specific references to provide more details. Copyright © 2014 SERAM. Published by Elsevier España, S.L.U. All rights reserved.

  8. Negative symptom domain prevalence across diagnostic boundaries: The relevance of diagnostic shifts.

    Science.gov (United States)

    Lyne, John; Renwick, Laoise; O'Donoghue, Brian; Kinsella, Anthony; Malone, Kevin; Turner, Niall; O'Callaghan, Eadbhard; Clarke, Mary

    2015-08-30

    Negative symptoms are included in diagnostic manuals as part of criteria for schizophrenia spectrum psychoses only, however some studies have found their presence in other diagnoses. This study sought to clarify negative symptom domain prevalence across diagnostic categories, while investigating whether negative symptoms predicted diagnostic shift over time. Scale for the Assessment of Negative Symptoms (SANS) data were collected at first presentation in 197 individuals presenting with first episode psychosis and again at one year follow-up assessment. Negative symptoms were highest among individuals with schizophrenia and among those whose diagnosis shifted from non-schizophrenia spectrum at baseline to schizophrenia spectrum at follow-up. In a non-schizophrenia spectrum group negative symptoms at baseline were not a significant predictor of diagnostic shift to schizophrenia spectrum diagnoses. The study suggests negative symptoms can present among individuals with non-schizophrenia spectrum diagnoses, although this is most relevant for individuals following diagnostic shift from non-schizophrenia spectrum to schizophrenia spectrum diagnoses. The findings support introduction of a negative symptom dimension when describing a range of psychotic illnesses, and indicate that further research investigating the evolution of negative symptoms in non-schizophrenia diagnoses is needed. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  9. Theoretical studies of flash x-ray diagnostics for fuel motion experiments

    International Nuclear Information System (INIS)

    Halbleib, J.A. Sr.; Phillips, A.R.

    1975-09-01

    The results of preliminary theoretical studies concerning the possible employment of short-pulse, high-current field emission diodes as sources for the flash x-ray diagnostics of fuel-pin motion are reported. The predicted thick-target photon environments are obtained from state-of-the-art coupled electron/photon transport models. Through qualitative figures of merit these environments are used to study the importance of source current and voltage. For a selected experimental configuration a comparison is made between the absolute flash x-ray imaging signals predicted for these environments and Monte Carlo/analytic calculations of absolute fission-gamma backgrounds. These preliminary data suggest that field emission sources operating at voltages in the 1-to 5-MeV range and at currents of the order of 100-kA or greater may be adequate diagnostic sources for test-pin configurations as complex as a full LMFBR subassembly

  10. Indications and new diagnostic techniques in micturating cystourethrographic studies

    International Nuclear Information System (INIS)

    Schuster, W.; Bruenger, J.

    1978-01-01

    Urological radiographic procedures on children are of great importance. The frequency of examinations is comparable to the number of Gl tract studies. In diagnosing chronically recurrent urinary tract infections, micturating cystourethrography is a valuable addition to excretory urography. Indications and performance of micturating cystourethrography at juvenile age are described. All measures reducing radiation exposure must be taken into consideration. New technological devices grant improved diagnostic information with a minimal radiation exposure for patients. (orig.) [de

  11. The architecture of diagnostic research

    DEFF Research Database (Denmark)

    Colli, Agostino; Fraquelli, Mirella; Casazza, Giovanni

    2014-01-01

    The diagnostic research process can be divided into five phases, designed to establish the clinical utility of a new diagnostic test - the index test. The aim of the present review is to illustrate the study designs that are appropriate for each diagnostic phase, using clinical examples regarding...

  12. Assessing the utility of diagnostic criteria: a multisite study on gender identity disorder.

    Science.gov (United States)

    Paap, Muirne C S; Kreukels, Baudewijntje P C; Cohen-Kettenis, Peggy T; Richter-Appelt, Hertha; de Cuypere, Griet; Haraldsen, Ira R

    2011-01-01

    Studies involving patients with gender identity disorder (GID) are inconsistent with regard to outcomes and often difficult to compare because of the vague descriptions of the diagnostic process. A multisite study is needed to scrutinize the utility and generality of different aspects of the diagnostic criteria for GID. To investigate the way in which the diagnosis-specific Diagnostic and Statistical Manual of Mental Disorders, 4th Edition, Text Revision criteria for GID were used to reach a psychiatric diagnosis in four European countries: the Netherlands (Amsterdam), Norway (Oslo), Germany (Hamburg), and Belgium (Ghent). The main goal was to compare item (symptom) characteristics across countries. The current study included all new applicants to the four GID clinics who were seen between January 2007 and March 2009, were at least 16 years of age at their first visit, and had completed the diagnostic assessment (N = 214, mean age = 32 ± 12.2 years). Mokken scale analysis, a form of Nonparametric Item Response Theory (NIRT) was performed. Operationalization and quantification of the core criteria A and B resulted in a 23-item score sheet that was filled out by the participating clinicians after they had made a diagnosis. We found that, when ordering the 23 items according to their means for each country separately, the rank ordering was similar among the four countries for 21 of the items. Furthermore, only one scale emerged, which combined criteria A and B when all data were analyzed together. Our results indicate that patients' symptoms were interpreted in a similar fashion in all four countries. However, we did not find support for the treatment of A and B as two separate criteria. We recommend the use of NIRT in future studies, especially in studies with small sample sizes and/or with data that show a poor fit to parametric IRT models. © 2010 International Society for Sexual Medicine.

  13. Diagnostic Strategy in APR1400

    International Nuclear Information System (INIS)

    Kim, Dongyoung; Kim, Jonghyun

    2013-01-01

    These features may bring out changes in operator tasks, changing the characteristics of tasks, or creating new tasks. Diagnostic strategy for identifying anomaly may be different especially in APR1400 from that in the analog control room due to the change of human-system interface, i.e. alarm system and display system. Since the first plant of APR1400 is being built at this moment, it is not known what strategies the operators will adopt in diagnosis tasks in the new operating environment. In this light, this paper aims at investigating operator's diagnostic strategies which are appropriate for APR1400. In order to collect data, several different approaches which are complementary are used to identify diagnostic strategies in the digital control room: analysis on audio/video recording of operation, observation in the simulator, and interview with the operators. The result shows that the digital control room introduces new strategies in the diagnosis, compared with the analog control room, and also changed the characteristics of strategies, mostly, by getting more support from the computerized system. This paper investigated how the digitalized control room may influence operator's diagnostic strategies. Several different approaches, i. e., audio/video record, observation of training, and the interview with operators, were used to gather information about the operator's behaviors. As a conclusion, this paper figured out that the digital control room introduces new strategies in the diagnosis, compared with the analog control room, and also changed the characteristics of the strategies, mostly, by getting more support from the computerized system. The operators interviewed also commented that the diagnosis in the APR1400 is quicker, more correct, and easier, compared with the analog control room

  14. Methods and tools for analysis and optimization of power plants

    Energy Technology Data Exchange (ETDEWEB)

    Assadi, Mohsen

    2000-09-01

    The most noticeable advantage of the introduction of the computer-aided tools in the field of power generation, has been the ability to study the plant's performance prior to the construction phase. The results of these studies have made it possible to change and adjust the plant layout to match the pre-defined requirements. Further development of computers in recent years has opened up for implementation of new features in the existing tools and also for the development of new tools for specific applications, like thermodynamic and economic optimization, prediction of the remaining component life time, and fault diagnostics, resulting in improvement of the plant's performance, availability and reliability. The most common tools for pre-design studies are heat and mass balance programs. Further thermodynamic and economic optimization of plant layouts, generated by the heat and mass balance programs, can be accomplished by using pinch programs, exergy analysis and thermoeconomics. Surveillance and fault diagnostics of existing systems can be performed by using tools like condition monitoring systems and artificial neural networks. The increased number of tools and their various construction and application areas make the choice of the most adequate tool for a certain application difficult. In this thesis the development of different categories of tools and techniques, and their application area are reviewed and presented. Case studies on both existing and theoretical power plant layouts have been performed using different commercially available tools to illuminate their advantages and shortcomings. The development of power plant technology and the requirements for new tools and measurement systems have been briefly reviewed. This thesis contains also programming techniques and calculation methods concerning part-load calculations using local linearization, which has been implemented in an inhouse heat and mass balance program developed by the author

  15. Study design requirements for RNA sequencing-based breast cancer diagnostics.

    Science.gov (United States)

    Mer, Arvind Singh; Klevebring, Daniel; Grönberg, Henrik; Rantalainen, Mattias

    2016-02-01

    Sequencing-based molecular characterization of tumors provides information required for individualized cancer treatment. There are well-defined molecular subtypes of breast cancer that provide improved prognostication compared to routine biomarkers. However, molecular subtyping is not yet implemented in routine breast cancer care. Clinical translation is dependent on subtype prediction models providing high sensitivity and specificity. In this study we evaluate sample size and RNA-sequencing read requirements for breast cancer subtyping to facilitate rational design of translational studies. We applied subsampling to ascertain the effect of training sample size and the number of RNA sequencing reads on classification accuracy of molecular subtype and routine biomarker prediction models (unsupervised and supervised). Subtype classification accuracy improved with increasing sample size up to N = 750 (accuracy = 0.93), although with a modest improvement beyond N = 350 (accuracy = 0.92). Prediction of routine biomarkers achieved accuracy of 0.94 (ER) and 0.92 (Her2) at N = 200. Subtype classification improved with RNA-sequencing library size up to 5 million reads. Development of molecular subtyping models for cancer diagnostics requires well-designed studies. Sample size and the number of RNA sequencing reads directly influence accuracy of molecular subtyping. Results in this study provide key information for rational design of translational studies aiming to bring sequencing-based diagnostics to the clinic.

  16. Development of knowledge acquisition methods for knowledge base construction for autonomous plants

    Energy Technology Data Exchange (ETDEWEB)

    Yoshikawa, S. [Power Reactor and Nuclear Fuel Development Corp., Oarai, Ibaraki (Japan). Oarai Engineering Center; Sasajima, M.; Kitamura, Y.; Ikeda, M.; Mizoguchi, R.

    1993-03-01

    In order to enhance safety and reliability of nuclear plant operation, it is strongly desired to construct diagnostic knowledge base without lacking, contradiction, and description inconsistency. Nowadays, an advanced method Knowledge Compiler` has been studied to acquire diagnostic knowledge, mainly based on qualitative reasoning technique, without accumulating heuristics by interviews. Until now, 2 methods to suppress the ambiguity observed when qualitative reasoning mechanism were applied to heat transport systems of nuclear power plants: In the first method, qualitative values are allocated to the system variables along with the causality direction, avoiding contradictions among plural variables in each qualitative constraint describing knowledge of deviation propagation, heat balance, or energy conservation. In the second method, all the qualitative information is represented as a set of simultaneous qualitative equations. And, an appropriate subset is selected so that the qualitative solutions of unknowns in this subset can be derived independently of the remaining part. A contrary method is applied for the selected subset to derive local solutions. Then the problem size is reduced by substituting solutions of the subset, in a recursive manner. In the previous report on this research project, complete computer softwares have been constructed based on these methods, and applied to a 2-loop heat transport system of a nuclear power plant. The detailed results are discussed in this report. In addition, an integrated configuration of diagnostic knowledge generation system of nuclear power plants is proposed, based upon the results and new foundings obtained through the research activities so far, and the future works to overcome remaining problems are also identified. (author)

  17. Neural network recognition of nuclear power plant transients

    International Nuclear Information System (INIS)

    Bartlett, E.B.; Danofsky, R.; Adams, J.; AlJundi, T.; Basu, A.; Dhanwada, C.; Kerr, J.; Kim, K.; Lanc, T.

    1993-01-01

    The objective of this report is to describe results obtained during the first year of funding that will lead to the development of an artificial neural network (ANN) fault - diagnostic system for the real - time classification of operational transients at nuclear power plants. The ultimate goal of this three-year project is to design, build, and test a prototype diagnostic adviser for use in the control room or technical support center at Duane Arnold Energy Center (DAEC); such a prototype could be integrated into the plant process computer or safety - parameter display system. The adviser could then warn and inform plant operators and engineers of plant component failures in a timely manner. This report describes the work accomplished in the first of three scheduled years for the project. Included herein is a summary of the first year's results as, well as individual descriptions of each of the major topics undertaken by the researchers. Also included are reprints of the articles written under this funding as well as those that were published during the funded period

  18. Protection study of a diagnostic system for electron beam at the output of an accelerator

    International Nuclear Information System (INIS)

    Rahmani, Kaouther; Yaacoubi, Imen

    2009-01-01

    The aim of this work is the determination of the conception of a protection system dedicated to protect a diagnostic system in the CNSTN. According to this study, the suitable material for the protection against the electrons in the plexiglas and the supermalloy to protect the future diagnostic system against the magnetic field. (Author)

  19. The development of a diagnostic and monitoring system for vibrating pipe branches

    International Nuclear Information System (INIS)

    Tanaka, Toshio; Suzuki, Shigeki; Nekomoto, Yoshitsugu; Tanaka, Mamoru

    1994-01-01

    This paper deals with a diagnostic and monitoring system for assessing the integrity of pipe branches, during the operation of the nuclear power plant. This system have been developed under the concept of ''easy to use without any sophisticated analysis'' and ''portable''. The accuracy of the diagnosis is based on the model optimization subsystem, which automatically modifies the numerical vibration model so as to fit its natural frequency to the actual natural frequency. The information obtained by this system may be reflected to a maintenance program of the plant to assure more reliable operation of the plant. (orig.)

  20. Individual patient data meta-analysis of diagnostic and prognostic studies in obstetrics, gynaecology and reproductive medicine

    NARCIS (Netherlands)

    Broeze, Kimiko A.; Opmeer, Brent C.; Bachmann, Lucas M.; Broekmans, Frank J.; Bossuyt, Patrick M. M.; Coppus, Sjors F. P. J.; Johnson, Neil P.; Khan, Khalid S.; ter Riet, Gerben; van der Veen, Fulco; van Wely, Madelon; Mol, Ben W. J.

    2009-01-01

    ABSTRACT: BACKGROUND: In clinical practice a diagnosis is based on a combination of clinical history, physical examination and additional diagnostic tests. At present, studies on diagnostic research often report the accuracy of tests without taking into account the information already known from

  1. A prospective study of the diagnostic utility of sputum Gram stain in pneumonia.

    Science.gov (United States)

    Anevlavis, Stavros; Petroglou, Niki; Tzavaras, Athanasios; Maltezos, Efstratios; Pneumatikos, Ioannis; Froudarakis, Marios; Anevlavis, Eleftherios; Bouros, Demosthenes

    2009-08-01

    Sputum Gram stain and culture have been said to be unreliable indicators of the microbiological diagnosis of bacterial pneumonia. The etiological diagnosis of pneumonia is surrounded by great degree of uncertainty. This uncertainty should be and can be calculated and incorporated in the diagnosis and treatment. To determine the diagnostic accuracy and diagnostic value of sputum Gram stain in etiological diagnosis and initial selection of antimicrobial therapy of bacterial community acquired pneumonia (CAP). DESIGN-METHOD: Prospective study of 1390 patients with CAP admitted January 2002-June 2008, to our institutions. Of the 1390 patients, 178 (12.8%) fulfilled the criteria for inclusion into this study (good-quality sputa and presence of the same microorganism in blood and sputum cultures which was used as gold standard for assessing the diagnostic accuracy and diagnostic value of sputum Gram stain). The sensitivity of sputum Gram stain was 0.82 for Pneumococcal pneumonia, 0.76 for Staphylococcal pneumonia, 0.79 for Haemophilus influenzae pneumonia and 0.78 for Gram-negative bacilli pneumonia. The specificity of sputum Gram stain was 0.93 for Pneumococcal pneumonia, 0.96 for Staphylococcal pneumonia, 0.96 for H. influenzae pneumonia and 0.95 for Gram-negative bacilli pneumonia. The positive likelihood ratio (LR+) was 11.58 for Pneumococcal pneumonia, 19.38 for Staphylococcal pneumonia, 16.84 for H. influenzae pneumonia, 14.26 for Gram-negative bacilli pneumonia. The negative likelihood ratio (LR-) was 0.20 for Pneumococcal pneumonia, 0.25 for Staphylococcal pneumonia, 0.22 for H. influenzae pneumonia, and 0.23 for Gram-negative bacilli pneumonia. Sputum Gram stain is a dependable diagnostic test for the early etiological diagnosis of bacterial CAP that helps in choosing orthological and appropriate initial antimicrobial therapy.

  2. Study on a self diagnostic monitoring system for an air-operated valve: development of a fault library

    International Nuclear Information System (INIS)

    Chai, Jang Bom; Kim, Yun Chul; Kim, Woo Shik; Cho, Hang Duke

    2004-01-01

    In the interest of nuclear power plant safety, a Self-Diagnostic Monitoring System (SDMS) is needed to monitor defects in safety-related components. An Air-Operated Valve (AOV) is one of the components to be monitored since the failure of its operation could potentially have catastrophic consequences. In this paper, a model of the AOV is developed with the parameters that affect the operational characteristics. The model is useful for both understanding the operation and correlating parameters and defects. Various defects are introduced in the experiments to construct a fault library, which will be used in a pattern recognition approach. Finally, the validity of the fault library is examined

  3. Nuclear Power Plant Lifetime Management Study (I)

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Sung Yull; Jeong, Ill Seok; Jang, Chang Heui; Song, Taek Ho; Song, Woo Young [Korea Electric Power Research Institute, Taejon (Korea, Republic of); Jin, Tae Eun [Korea Power Engineering Company Consulting and Architecture Engineers, (Korea, Republic of); Kim, Woo Chul [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1997-12-31

    As the operation-year of nuclear power plant increases and finding sites for new nuclear power plant becomes harder, a comprehensive and systematic nuclear plant lifetime management(PLIM) program including life extension has to be established for stable and safe supply of electricity. A feasibility study was conducted to systematically evaluate technical, economic and regulatory aspect of plant lifetime managements and plant life extension for Kori-1 nuclear power plant. For technical evaluation of nuclear power plant, 13 major components were selected for lifetime evaluation by screening system. structure, and components(SSCs) of the plant. It was found that except reactor pressure vessel, which needs detailed integrity analysis, and low pressure turbine, which is scheduled to be replaced, 11 out of 13 major components have sufficient service life, for more than 40 years. Because domestic rules and regulations related to license renewal has not yet been written, review on the regulatory aspect of life extensions was conducted using US NRC rules and regulations. A cooperative effort with nuclear regulatory body is needed for early completion of license renewal rules and regulations. For economic evaluation of plant lifetime extension, a computer program was developed and used. It was found that 10 to 20 year of extension operation of Kori-1 nuclear power plant was proved. Based on the results, next phase of plant lifetime management program for detailed lifetime evaluation and presenting detailed implementation schedule for plant refurbishment for lifetime extension should be followed. (author). 74 refs., figs.

  4. Nuclear Power Plant Lifetime Management Study (I)

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Sung Yull; Jeong, Ill Seok; Jang, Chang Heui; Song, Taek Ho; Song, Woo Young [Korea Electric Power Research Institute, Taejon (Korea, Republic of); Jin, Tae Eun [Korea Power Engineering Company Consulting and Architecture Engineers, (Korea, Republic of); Kim, Woo Chul [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1996-12-31

    As the operation-year of nuclear power plant increases and finding sites for new nuclear power plant becomes harder, a comprehensive and systematic nuclear plant lifetime management(PLIM) program including life extension has to be established for stable and safe supply of electricity. A feasibility study was conducted to systematically evaluate technical, economic and regulatory aspect of plant lifetime managements and plant life extension for Kori-1 nuclear power plant. For technical evaluation of nuclear power plant, 13 major components were selected for lifetime evaluation by screening system. structure, and components(SSCs) of the plant. It was found that except reactor pressure vessel, which needs detailed integrity analysis, and low pressure turbine, which is scheduled to be replaced, 11 out of 13 major components have sufficient service life, for more than 40 years. Because domestic rules and regulations related to license renewal has not yet been written, review on the regulatory aspect of life extensions was conducted using US NRC rules and regulations. A cooperative effort with nuclear regulatory body is needed for early completion of license renewal rules and regulations. For economic evaluation of plant lifetime extension, a computer program was developed and used. It was found that 10 to 20 year of extension operation of Kori-1 nuclear power plant was proved. Based on the results, next phase of plant lifetime management program for detailed lifetime evaluation and presenting detailed implementation schedule for plant refurbishment for lifetime extension should be followed. (author). 74 refs., figs.

  5. PSYCHOLOGICAL DIAGNOSTICS OF STUDENTS ADAPTATION TO UNIVERSITY STUDIES

    Directory of Open Access Journals (Sweden)

    Olga A. Molokova

    2015-01-01

    Full Text Available Aim. The solution version of one of problems of psychology andpedagogical escort of students at the initial stage of their adaptation to training in higher education institution is stated in the study. Such maintenance obligatory includes diagnostics of a psychological state of pupils that in a traditional state demands considerable expenses by as teachers’ and first-year students’ forces and time. Possibility of elimination of this shortcoming is presented.Methods. The methods involve the modified Sklyayn’s technique which description is presented in K. Rogers’s works; the technique of the personal differential definition; the technique of definition of the psychological satisfaction in various vital spheres. Students’ relation to the research was found out during anonymous poll.Results. It is shown that, despite the positive relation to psychological researches from the majority of respondents, there is a problem of the obvious or latent unwillingness of some first-year students to participate in surveys and test work caused by work content and its duration. The alternative to tiresome measurements of indicators of adaptation of pupils to training in higher education institution is presented – the express diagnostics reduce time of monitoring and allow teachers to get students interested. Comparison of the results received at use of Sklyayn’s technique and a technique «Personal differential» shows that they investigate the same phenomenon at nonverbal and verbal levels: correlation of persons’ «real self» and «ideal self». However, if creation of verbal formulations of the person relation to what he/she is, and to what he/she wants to be, can cause difficulties by the examinee, the nonverbal diagnostics turned to subconsciousness, is not only simpler, but also reflects a psychological state of the person more precisely.Scientific novelty. Modification of the technique by Sklyayn is proposed; it

  6. Diagnostic and monitoring systems produced in Vuje, Okruzna 5, 918 64 Trnava, Slovak Republic

    International Nuclear Information System (INIS)

    Oksa, G.; Bahna, J.; Murin, V.; Kucharek, P.; Smutny, S.

    1996-01-01

    Based on the 20 years experience in on-line vibration diagnostics of mechanical components in the primary circuit of nuclear power plant PWR WWER-440, Vuje, Okruzna 5, 918 64 Trnava produces its own diagnostic and monitoring systems since 1990. The variety of diagnostic systems includes: loose part monitoring system (LPMS), monitoring system of main circulating pumps (MCPMS), vibration monitoring system (LVMS), leakage monitoring system (LMS). The emphasis in the hardware solution is put on the design modularity and versatility so that many subcomponents (circuit boards) are common or highly similar for all systems. Using exclusively digital data for processing enhances the reliability of the measurements and allows the easy data transportation from one computer to another (e.g., for more sophisticated analysis). Trends in the software development follow the similar path as for the hardware solution - namely, the modularity and versatility of software is the imperative goal. The modern operating systems also incorporate the ability of network communication, which is crucial for the integration of stand-alone diagnostic systems into nuclear power plants information system. So far a number of systems have been successfully installed: 6 LPMSs (Jaslovske Bohunice, Dukovany), 4 MCPMs (Jaslovske Bohunice) and 2 LVMSs (Jaslovske Bohunice), all systems operate in PWR WWER-440 environment. Another diagnostic systems are under construction: 2 LPMSs (Temelin, PWR WWER-1000), 2 MCMSs (Mochovce - PWR WWER-440) and 2 LMSs (Jaslovske Bohunice). (author). 1 fig

  7. Diagnostic and monitoring systems produced in Vuje, Okruzna 5, 918 64 Trnava, Slovak Republic

    Energy Technology Data Exchange (ETDEWEB)

    Oksa, G; Bahna, J; Murin, V; Kucharek, P; Smutny, S [Vyskumny Ustav Jadrovych Elektrarni, Trnava (Slovakia)

    1997-12-31

    Based on the 20 years experience in on-line vibration diagnostics of mechanical components in the primary circuit of nuclear power plant PWR WWER-440, Vuje, Okruzna 5, 918 64 Trnava produces its own diagnostic and monitoring systems since 1990. The variety of diagnostic systems includes: loose part monitoring system (LPMS), monitoring system of main circulating pumps (MCPMS), vibration monitoring system (LVMS), leakage monitoring system (LMS). The emphasis in the hardware solution is put on the design modularity and versatility so that many subcomponents (circuit boards) are common or highly similar for all systems. Using exclusively digital data for processing enhances the reliability of the measurements and allows the easy data transportation from one computer to another (e.g., for more sophisticated analysis). Trends in the software development follow the similar path as for the hardware solution - namely, the modularity and versatility of software is the imperative goal. The modern operating systems also incorporate the ability of network communication, which is crucial for the integration of stand-alone diagnostic systems into nuclear power plants information system. So far a number of systems have been successfully installed: 6 LPMSs (Jaslovske Bohunice, Dukovany), 4 MCPMs (Jaslovske Bohunice) and 2 LVMSs (Jaslovske Bohunice), all systems operate in PWR WWER-440 environment. Another diagnostic systems are under construction: 2 LPMSs (Temelin, PWR WWER-1000), 2 MCMSs (Mochovce - PWR WWER-440) and 2 LMSs (Jaslovske Bohunice). (author). 1 fig.

  8. 2012 HIV Diagnostics Conference: the molecular diagnostics perspective.

    Science.gov (United States)

    Branson, Bernard M; Pandori, Mark

    2013-04-01

    2012 HIV Diagnostic Conference Atlanta, GA, USA, 12-14 December 2012. This report highlights the presentations and discussions from the 2012 National HIV Diagnostic Conference held in Atlanta (GA, USA), on 12-14 December 2012. Reflecting changes in the evolving field of HIV diagnostics, the conference provided a forum for evaluating developments in molecular diagnostics and their role in HIV diagnosis. In 2010, the HIV Diagnostics Conference concluded with the proposal of a new diagnostic algorithm which included nucleic acid testing to resolve discordant screening and supplemental antibody test results. The 2012 meeting, picking up where the 2010 meeting left off, focused on scientific presentations that assessed this new algorithm and the role played by RNA testing and new developments in molecular diagnostics, including detection of total and integrated HIV-1 DNA, detection and quantification of HIV-2 RNA, and rapid formats for detection of HIV-1 RNA.

  9. NPP operator support in decision making - diagnostics of the operation failures using fuzzy logic

    International Nuclear Information System (INIS)

    Petruzela, I.

    2000-01-01

    In large complex systems such as nuclear power plants (NPP) and chemical industry plants, various subsystems fulfil the needs of process control and safety. Continued operation of these systems has both economic and safety implications. Electric utilities seek continuously to improve the operation of power generating stations. The improvement in the NPP Dukovany (4 x 440 MW) is related to the introduction of the plant to frequency control, meaning that the plant is operated not only in the base load operational mode but in the load follow mode as well. To achieve the improvement of plant operation, it was necessary to provide modifications to the plant control system, plant information system and diagnostics. This chapter deals with utilisation of artificial intelligence (AI) methods in implementation of these plant modifications. (orig.)

  10. Experimental and numerical studies on liquid wicking into filter papers for paper-based diagnostics

    International Nuclear Information System (INIS)

    Liu, Zhi; Hu, Jie; Zhao, Yimeng; Qu, Zhiguo; Xu, Feng

    2015-01-01

    Paper-based diagnostics have shown promising potential applications in human disease surveillance and food safety analysis at the point-of-care (POC). The liquid wicking behavior in diagnostic fibrous paper plays an important role in development of paper-based diagnostics. In the current study, we performed experimental and numerical research on the liquid wicking height and mass with three width strips into filter paper. The effective porosity could be conveniently measured in the light of the linear correlation between wicking height and mass by the experimental system. A modified model with considering evaporation effect was proposed to predict wicking height and mass. The predicted wicking height and mass using the evaporation model was much closer to the experimental data compared with the model without evaporation. The wicking speed initially decreased significantly and then maintained at a constant value at lower level. The evaporation effect tends to reduce the wicking flow speed. More wicking mass could be obtained at larger strip width but the corresponding reagent loss became significant. The proposed model with evaporation paved a way to understanding the fundamental of fluid flow in diagnostic paper and was essential to provide meaningful and useful reference for the research and development of paper-based diagnostics devices. - Highlights: • A model with considering evaporation was proposed to predict wicking height and mass. • Flow characteristics of filter paper were experimentally and theoretically studied. • Effective porosity could be conveniently measured by the experimental platform. • The evaporation effect tended to reduce the wicking flow speed

  11. Compounding diagnostic delays: a qualitative study of point-of-care testing in South Africa.

    Science.gov (United States)

    Engel, Nora; Davids, Malika; Blankvoort, Nadine; Pai, Nitika Pant; Dheda, Keertan; Pai, Madhukar

    2015-04-01

    Successful point-of-care (POC) testing (completion of test-and-treat cycle in one patient encounter) has immense potential to reduce diagnostic and treatment delays, and improve patient and public health outcomes. We explored what tests are done and how in public/private, rural/urban hospitals and clinics in South Africa and whether they can ensure successful POC testing. This qualitative research study examined POC testing across major diseases in Cape Town, Durban and Eastern Cape. We conducted 101 semi-structured interviews and seven focus group discussions with doctors, nurses, community health workers, patients, laboratory technicians, policymakers, hospital managers and diagnostic manufacturers. In South Africa, diagnostics are characterised by a centralised system. Most tests conducted on the spot can be made to work successfully as POC tests. The majority of public/private clinics and smaller hospitals send samples via couriers to centralised laboratories and retrieve results the same way, via internet, fax or phone. The main challenge to POC testing lies in transporting samples and results, while delays risk patient loss from diagnostic/treatment pathways. Strategies to deal with associated delays create new problems, such as artificially prolonged turnaround times, strains on human resources and quality of testing, compounding additional diagnostic and treatment delays. For POC testing to succeed, particular characteristics of diagnostic ecosystems and adaptations of professional practices to overcome associated challenges must be taken into account. © 2014 John Wiley & Sons Ltd.

  12. Fusion power plant studies in Europe

    International Nuclear Information System (INIS)

    Maisonnier, D.

    2007-01-01

    The European fusion programme is reactor oriented and it is aimed at the successive demonstration of the scientific, the technological and the economic feasibility of fusion power. For a reactor-oriented fusion development programme, it is essential to have a clear idea of the ultimate goal of the programme, namely a series of models of fusion power plants, in order to define the correct strategy and to assess the pertinence of the on-going activities. The European Power Plant Conceptual Study (PPCS) has been a study of conceptual designs for commercial fusion power plants. It focused on five power plant models, named PPCS A, B, AB, C and D, which are illustrative of a wider spectrum of possibilities. They are all based on the tokamak concept and they have approximately the same net electrical power output, 1500 MWe. These span a range from relatively near-term, based on limited technology and plasma physics extrapolations, to an advanced conception. All five PPCS plant models differ substantially from the models that formed the basis of earlier European studies. They also differ from one another, which lead to differences in economic performance and in the details of safety and environmental impacts. The main emphasis of the PPCS was on system integration. Systems analyses were used to produce self-consistent plant parameter sets with approximately optimal economic characteristics for all models. In the PPCS models, the favourable, inherent, features of fusion have been exploited to provide substantial safety and environmental advantages. The broad features of the safety and environmental conclusions of previous studies have been confirmed and demonstrated with increased confidence. The PPCS study highlighted the need for specific design and R and D activities, in addition to those already underway within the European long term R and D programme, as well as the need to clarify the concept of DEMO, the device that will bridge the gap between ITER and the first

  13. Radioactive zinc in soil-plant relationship studies

    International Nuclear Information System (INIS)

    Karimian, N.

    1986-01-01

    Zinc is one of the elements whose essentiality for plant growth and development has been proved beyond any doubt. Plant life and consequently the crop yield is impossible without zinc. The results of chemical, greenhouse, and field experiments on soils of Shiraz show that their level of available zinc for some crops is inadequate, despite the fact that the total amount of zinc in these soils may be relatively high. Obtaining the maximum yield, therefore, requires that either supplemental zinc be applied as chemical fertilizers or make the endogenous zinc more available to plants through some management practices. One of the isotopes of zinc, i.e. 65 Zn, is radioactive and has a detectable radiation which makes it suitable for tracer studies of zinc in soil, water, plant and animal. These studies help in understanding the soil plant relationships of zinc which in turn help to determine the optimum conditions of obtaining maximum yield. This paper presents and analyzes the results of some selected experiments to show different techniques of using radioactive zinc in understanding the behavior of zinc in soil and plant. Suggestions are also made of using this radioisotope in understanding the reactions of zinc in soils of Iran

  14. Idaho Chemical Processing Plant and Plutonium-Uranium Extraction Plant phaseout/deactivation study

    International Nuclear Information System (INIS)

    Patterson, M.W.; Thompson, R.J.

    1994-01-01

    The decision to cease all US Department of Energy (DOE) reprocessing of nuclear fuels was made on April 28, 1992. This study provides insight into and a comparison of the management, technical, compliance, and safety strategies for deactivating the Idaho Chemical Processing Plant (ICPP) at Westinghouse Idaho Nuclear Company (WINCO) and the Westinghouse Hanford Company (WHC) Plutonium-Uranium Extraction (PUREX) Plant. The purpose of this study is to ensure that lessons-learned and future plans are coordinated between the two facilities

  15. How to appraise a diagnostic test

    Directory of Open Access Journals (Sweden)

    Ramanitharan Manikandan

    2011-01-01

    Full Text Available Urologists frequently encounter problems in making a clinical diagnosis whose resolution requires the use of diagnostic tests. With an ever increasing choice of investigations being available, the urologist often has to decide which diagnostic test(s will best resolve the patient′s diagnostic problem. In this article, we aim to help the urologist understand how to critically appraise studies on diagnostic tests and make a rational choice. This article presents the guiding principles in scientifically assessing studies on diagnostic tests by proposing a clinical scenario. The authors describe a standardized protocol to assess the validity of the test and its relevance to the clinical problem that can help the urologist in decision making. The three important issues to be considered when evaluating the validity of the study are to identify how the study population was chosen, how the test was performed and whether there is a comparison to the gold standard test so as to confirm or refute the diagnosis. Then, the urologist would need to know the probability of the test in providing the correct diagnosis in an individual patient in order to decide about its utility in solving the diagnostic dilemma. By performing the steps described in this article, the urologist would be able to critically appraise diagnostic studies and draw meaningful conclusions about the investigations in terms of validity, results and its applicability to the patient′s problem. This would provide a scientific basis for using diagnostic tests for improving patient care.

  16. Effect Size (Cohen's d of Cognitive Screening Instruments Examined in Pragmatic Diagnostic Accuracy Studies

    Directory of Open Access Journals (Sweden)

    Andrew J. Larner

    2014-07-01

    Full Text Available Background/Aims: Many cognitive screening instruments (CSI are available to clinicians to assess cognitive function. The optimal method comparing the diagnostic utility of such tests is uncertain. The effect size (Cohen's d, calculated as the difference of the means of two groups divided by the weighted pooled standard deviations of these groups, may permit such comparisons. Methods: Datasets from five pragmatic diagnostic accuracy studies, which examined the Mini-Mental State Examination (MMSE, the Mini-Mental Parkinson (MMP, the Six-Item Cognitive Impairment Test (6CIT, the Montreal Cognitive Assessment (MoCA, the Test Your Memory test (TYM, and the Addenbrooke's Cognitive Examination-Revised (ACE-R, were analysed to calculate the effect size (Cohen's d for the diagnosis of dementia versus no dementia and for the diagnosis of mild cognitive impairment versus no dementia (subjective memory impairment. Results: The effect sizes for dementia versus no dementia diagnosis were large for all six CSI examined (range 1.59-1.87. For the diagnosis of mild cognitive impairment versus no dementia, the effect sizes ranged from medium to large (range 0.48-1.45, with MoCA having the largest effect size. Conclusion: The calculation of the effect size (Cohen's d in diagnostic accuracy studies is straightforward. The routine incorporation of effect size calculations into diagnostic accuracy studies merits consideration in order to facilitate the comparison of the relative value of CSI.

  17. Plasma diagnostic reflectometry

    International Nuclear Information System (INIS)

    Cohen, B.I.; Afeyan, B.B.; Garrison, J.C.; Kaiser, T.B.; Luhmann, N.C. Jr.; Domier, C.W.; Chou, A.E.; Baang, S.

    1996-01-01

    Theoretical and experimental studies of plasma diagnostic reflectometry have been undertaken as a collaborative research project between the Lawrence Livermore National Laboratory (LLNL) and the University of California Department of Applied Science Plasma Diagnostics Group under the auspices of the Laboratory Directed Research and Development Program at LLNL. Theoretical analyses have explored the basic principles of reflectometry to understand its limitations, to address specific gaps in the understanding of reflectometry measurements in laboratory experiments, and to explore extensions of reflectometry such as ultra-short-pulse reflectometry. The theory has supported basic laboratory reflectometry experiments where reflectometry measurements can be corroborated by independent diagnostic measurements

  18. Serum and urine metabolomics study reveals a distinct diagnostic model for cancer cachexia

    Science.gov (United States)

    Yang, Quan‐Jun; Zhao, Jiang‐Rong; Hao, Juan; Li, Bin; Huo, Yan; Han, Yong‐Long; Wan, Li‐Li; Li, Jie; Huang, Jinlu; Lu, Jin

    2017-01-01

    Abstract Background Cachexia is a multifactorial metabolic syndrome with high morbidity and mortality in patients with advanced cancer. The diagnosis of cancer cachexia depends on objective measures of clinical symptoms and a history of weight loss, which lag behind disease progression and have limited utility for the early diagnosis of cancer cachexia. In this study, we performed a nuclear magnetic resonance‐based metabolomics analysis to reveal the metabolic profile of cancer cachexia and establish a diagnostic model. Methods Eighty‐four cancer cachexia patients, 33 pre‐cachectic patients, 105 weight‐stable cancer patients, and 74 healthy controls were included in the training and validation sets. Comparative analysis was used to elucidate the distinct metabolites of cancer cachexia, while metabolic pathway analysis was employed to elucidate reprogramming pathways. Random forest, logistic regression, and receiver operating characteristic analyses were used to select and validate the biomarker metabolites and establish a diagnostic model. Results Forty‐six cancer cachexia patients, 22 pre‐cachectic patients, 68 weight‐stable cancer patients, and 48 healthy controls were included in the training set, and 38 cancer cachexia patients, 11 pre‐cachectic patients, 37 weight‐stable cancer patients, and 26 healthy controls were included in the validation set. All four groups were age‐matched and sex‐matched in the training set. Metabolomics analysis showed a clear separation of the four groups. Overall, 45 metabolites and 18 metabolic pathways were associated with cancer cachexia. Using random forest analysis, 15 of these metabolites were identified as highly discriminating between disease states. Logistic regression and receiver operating characteristic analyses were used to create a distinct diagnostic model with an area under the curve of 0.991 based on three metabolites. The diagnostic equation was Logit(P) = −400.53 – 481.88

  19. Weeds as agricultural constraint in Benin: results of a diagnostic study

    NARCIS (Netherlands)

    Vissoh, P.V.; Gbèhounou, G.; Ahanchedé, A.; Kuyper, T.W.; Röling, N.G.

    2004-01-01

    Weeds are an emerging constraint on crop production, as a result of population pressure and more intensive use of cultivated land. A diagnostic study was carried out from June through August 2002 in the five agro-ecological zones of Benin (1) to identify the relative importance of weeds among major

  20. Design of XML-based plant data model

    International Nuclear Information System (INIS)

    Nair, Preetha M.; Padmini, S.; Gaur, Swati; Diwakar, M.P.

    2013-01-01

    XML has emerged as an open standard for exchanging structured data on various platforms to handle rich, nested, complex data structures. XML with its flexible tree-like data structure allows a more natural representation as compared to traditional databases. In this paper we present data model for plant data acquisition systems captured using XML technologies. Plant data acquisition systems in a typical Nuclear Power Plant consists of embedded nodes at the first tier and operator consoles at the second tier for operator operation, interaction and display of Plant parameters. This paper discusses a generic data model that was designed to capture process, network architecture, communication/interface protocol and diagnostics aspects required for a Nuclear Power Plant. (author)

  1. Computerized systems for on-line management of failures: a state-of-the-art discussion of alarm systems and diagnostic systems applied in the nuclear industry

    International Nuclear Information System (INIS)

    Kim, I.S.

    1994-01-01

    It is now well perceived in the nuclear industry that improving plant information systems is vital for enhancing the operational safety of nuclear power plants. Considerable work is underway worldwide to support operators' decision-making, particularly in their difficult tasks of managing process anomalies on-line. The work includes development of (1) advanced alarm systems, such as various kinds of computer-based alarm processing systems, Critical Function Monitoring System, Success Path Monitoring System and Safety Assessment System II, and (2) real-timer diagnostic systems, such as Disturbance Analysis System, Maryland Operator Advisory System II, Model-Integrated Diagnostic Analysis System, Diagnosis System using Knowledge Engineering Technique, Detailed Diagnosis, and Operator Advisor System. This paper presents a state-of-the-art review of plant information systems for on-line management of failures in nuclear power plants, focusing on the methodological features of computerized alarm systems and diagnostic systems. (author)

  2. Feasibility study of component risk ranking for plant maintenance

    International Nuclear Information System (INIS)

    Ushijima, Koji; Yonebayashi, Kenji; Narumiya, Yoshiyuki; Sakata, Kaoru; Kumano, Tetsuji

    1999-01-01

    Nuclear power is the base load electricity source in Japan, and reduction of operation and maintenance cost maintaining or improving plant safety is one of the major issues. Recently, Risk Informed Management (RIM) is focused as a solution. In this paper, the outline regarding feasibility study of component risk ranking for plant maintenance for a typical Japanese PWR plant is described. A feasibility study of component risk raking for plant maintenance optimization is performed on check valves and motor-operated valves. Risk ranking is performed in two steps using probabilistic analysis (quantitative method) for risk ranking of components, and deterministic examination (qualitative method) for component review. In this study, plant components are ranked from the viewpoint of plant safety / reliability, and the applicability for maintenance is assessed. As a result, distribution of maintenance resources using risk ranking is considered effective. (author)

  3. Power-plant-related estuarine zooplankton studies

    International Nuclear Information System (INIS)

    Sage, L.E.; Olson, M.M.

    1981-01-01

    In-plant studies examining the effects of entrainment on zooplankton and field studies examining zooplankton abundance, composition, and distribution in the Chesapeake Bay in the vicinity of Calvert Cliffs Nuclear Power Plant have been conducted from 1974 to the present. The evolution of these studies, with particular emphasis on design and statistical treatment, is discussed. Entrainment study designs evolved from discrete sampling episodes at 4-h intervals over 24 h to a time-series sampling design in which sampling took place every 30 min over 24 and 48-h periods. The near-field study design and samping methods have included replicated net tows, using 0.5-m nets, and replicated and nonreplicated pumped sampling, using a high-speed centrifugal pump. 16 refs

  4. Studies in training nuclear plant personnel

    International Nuclear Information System (INIS)

    Hamlin, K.W.

    1987-01-01

    One of the lessons learned from the Three Mile Island (TMI) accident was that the nuclear industry was ineffective in learning from previous events at other plants. As training programs and methods have improved since TMI, the nuclear industry has searched for effective methods to teach the lessons learned from industry events. The case study method has great potential as a solution. By reviewing actual plant events in detail, trainees can be challenged with solving actual problems. When used in a seminar or discussion format, these case studies also help trainees compare their decision-making processes with other trainees, the instructor, and the personnel involved in the actual case study event

  5. Chemical and pharmacognostical characterization of two Malaysian plants both known as Ajisamat

    Directory of Open Access Journals (Sweden)

    Tengku Azlan S. Tengku Mohamad

    Full Text Available Ajisamat, an herb commonly used as an aphrodisiac in the Malaysian traditional medicine, corresponds to two different species from different families - Salacia macrophylla Blume, Celastraceae, and Prismatomeris glabra (Korth. Valeton, Rubiaceae. Macromorphological inspection of the vegetative parts both plants reveals only a slight difference in the arrangement of the petioles. Microscopic investigation of the plants roots used as crude drugs revealed however distinctive anatomical features. Prismatic calcium oxalate crystals and banded paratracheal parenchyma are characteristics of S. macrophylla while P. glabradisplays an abundance as crystals. Other features such as vessels diameters and arrangements are also of diagnostic importance. Some of these characters were also identified in the powder of thes e plant materials and proposed for diagnostic purpose. The values for extraction of ethanol and water as well as total ash, acid-insoluble ash, water-soluble ash and sulfated ash were determined for both plants. Phytochemical studies were carried out on hexane and chloroform extracts of S. macrophylla and methanolic extract of P. glabra. S. macrophylla was shown to contain highly oxidized pentacyclic triterpenes while P. glabra contains anthraquinones. The pharmacognostical and hytochemical information can be utilised as the identification tools for Salacia macrophylla and Prismatomeris glabra

  6. German risk study 'nuclear power plants, phase B'

    International Nuclear Information System (INIS)

    Heuser, F.W.

    1989-01-01

    The results of the German risk study 'Nuclear power plants, phase B' indicate that an accident in a nuclear power plant which cannot be managed by the safety systems according to design, is extremely improbable: Its probability is at about 3 to 100,000 per year and plant. Even if the safety systems fail, emergency measures can be effected in a nuclear power plant to prevent an accident. These in-plant emergency measures diminish the probability of a core meltdown to about 4 to 1,000,000 per year and plant. Hence, the accident risk is greatly reduced. The information given by the author are to smooth the emotional edge in the discussion about the safety of nuclear power plants. (orig.) [de

  7. Diagnostic Strategy in APR1400

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Dongyoung; Kim, Jonghyun [KEPCO International Nuclear Graduate School, Ulsan (Korea, Republic of)

    2013-05-15

    These features may bring out changes in operator tasks, changing the characteristics of tasks, or creating new tasks. Diagnostic strategy for identifying anomaly may be different especially in APR1400 from that in the analog control room due to the change of human-system interface, i.e. alarm system and display system. Since the first plant of APR1400 is being built at this moment, it is not known what strategies the operators will adopt in diagnosis tasks in the new operating environment. In this light, this paper aims at investigating operator's diagnostic strategies which are appropriate for APR1400. In order to collect data, several different approaches which are complementary are used to identify diagnostic strategies in the digital control room: analysis on audio/video recording of operation, observation in the simulator, and interview with the operators. The result shows that the digital control room introduces new strategies in the diagnosis, compared with the analog control room, and also changed the characteristics of strategies, mostly, by getting more support from the computerized system. This paper investigated how the digitalized control room may influence operator's diagnostic strategies. Several different approaches, i. e., audio/video record, observation of training, and the interview with operators, were used to gather information about the operator's behaviors. As a conclusion, this paper figured out that the digital control room introduces new strategies in the diagnosis, compared with the analog control room, and also changed the characteristics of the strategies, mostly, by getting more support from the computerized system. The operators interviewed also commented that the diagnosis in the APR1400 is quicker, more correct, and easier, compared with the analog control room.

  8. Pharmacognostic evaluation of leaf of Cordia macleodii Hook., An ethnomedicinally important plant.

    Science.gov (United States)

    Bhide, Bhargav; Pillai, A P G; Shukla, V J; Acharya, R N

    2011-04-01

    Plants of ethnomedicinal importance have contributed for the development of many new pharmacologically effective molecules/chemical entities to modern medicine. India, the country having one of the richest biodiversity of its flora in its forest, with numerous tribal inhabitants, is able to contribute a lot from ethnomedicine to the ailing humanity. Cordia macleodii Hook. (Boraginaceae), an ethnomedicinal plant has been highlighted for its wound healing, aphrodisiac and hepatoprotective activities. It is a medium-sized tree, known as Panki/Shikari by the tribals, rarely found in the forests of Orissa, Chhattisgarh and Madhya Pradesh. So far, the plant has been studied neither for its pharmacognostical characters nor for its pharmacological actions except its hepatoprotective activity. Hence, it has been selected for a detailed investigation which includes pharmacognostic study of its leaf to find out the diagnostic characters and preliminary physicochemical analysis. Results of the study will help in identifying the plant pharmacognostically. Presence of alkaloids, glycosides and tannins were found during the study.

  9. Development of a high cycle vibration fatigue diagnostic system with non-contact vibration sensing

    International Nuclear Information System (INIS)

    Yoshitsugu, Nekomoto; Satoshi, Kiriyama; Moritatsu, Nishimura; Kenji, Matsumoto; Eiji, O'shima

    2001-01-01

    Nuclear power plants have a large number of pipes. Of these small-diameter pipe branches in particular are often damaged due to high-cycle fatigue. In order to ensure the reliability of a plant it is important to detect the fatigues in pipe branches at an early stage and to develop the technology to predict and diagnose the advancement of fatigue. Further, in order to carry out the diagnosis of the piping system effectively during operation, non-contact evaluation is useful. Hence, we have developed a 'high-cycle fatigue diagnostic system with non-contact vibration sensing', where the vibration of the pipe branch is measured using a non-contact sensor. Since the contents of the developed sensor technology has already been reported, this paper mainly describes the newly developed high-cycle fatigue diagnostic system. (authors)

  10. Plasma diagnostics on large tokamaks

    International Nuclear Information System (INIS)

    Orlinskij, D.V.; Magyar, G.

    1988-01-01

    The main tasks of the large tokamaks which are under construction (T-15 and Tore Supra) and of those which have already been built (TFTR, JET, JT-60 and DIII-D) together with their design features which are relevant to plasma diagnostics are briefly discussed. The structural features and principal characteristics of the diagnostic systems being developed or already being used on these devices are also examined. The different diagnostic methods are described according to the physical quantities to be measured: electric and magnetic diagnostics, measurements of electron density, electron temperature, the ion components of the plasma, radiation loss measurements, spectroscopy of impurities, edge diagnostics and study of plasma stability. The main parameters of the various diagnostic systems used on the six large tokamaks are summarized in tables. (author). 351 refs, 44 figs, 22 tabs

  11. NPP Temelin automatic monitoring and diagnostic system of secondary side of the unit 1

    International Nuclear Information System (INIS)

    Heidenreich, S.; Pisl, M.; Drab, F.

    1997-01-01

    Two measuring and evaluating systems by SKODA PRAHA are described, designed for the Temelin nuclear power plant: a permanent secondary side diagnostic system for technology monitoring in the period of startup and operation; and the system of physical and power starting-up for monitoring during the first and repeated startup. The purposes of both systems are outlined. The scope of diagnostics covered and the functioning of the secondary side system is dealt with in some detail. (A.K.)

  12. Diagnosing component faults in a generic nuclear power plant using counterfactual and temporal reasoning

    International Nuclear Information System (INIS)

    Oehrstroem, P.; Nielsen, F.R.; Pedersen, S.A.

    1992-01-01

    The subject of main interest is the logical and epistemological aspects of diagnostic reasoning. The aim was to understand the role of conditionals and causality in this respect. A model of causal and temporal reasoning was developed and evaluated in a controlled but complex setting. The generic nuclear power plant was used as a test ground. The coherence and scope of a logical theory of diagnostic reasoning was studied in order to discover whether the theory constitutes an adequate tool for making correct diagnoses of component faults in a generic nuclear power plant. A diagnosing system based on the CIMP system was run on a computer model of a nuclear power plant, various errors were then introduced. The aim of the diagnosis is mainly explanation and only partly repair. The causal field defines a conceptual framework within which the diagnostic purpose is given and within which various diagnostic possibilities and causal relationships are given, here with regard to error detection in a control room. The causal field is tacitly given and related to the operator's training and experience. The logical aspects of the problem of the diagnosis is described. The computer model is described and the symptom language is introduced. The process of reasoning about the possible diagnosis is presented. The utilization of ideas similiar to the heuristic classification is discussed. A data base command language for manipulating lists of symptoms is described and the design of a CIMP user interface for symptom language visualization is outlined. (AB)

  13. An improved method of DNA extraction from plants for pathogen ...

    African Journals Online (AJOL)

    Polymerase chain reaction (PCR)-based applications in plant molecular biology and molecular diagnostics for plant pathogens require good quality DNA for reliable and reproducible results. Leaf tissue is often the choice for DNA extraction, but the use of other sources such as tubers, stems, or seeds, is not uncommon.

  14. Predictive ability of an early diagnostic guess in patients presenting with chest pain; a longitudinal descriptive study.

    Science.gov (United States)

    Verdon, François; Junod, Michel; Herzig, Lilli; Vaucher, Paul; Burnand, Bernard; Bischoff, Thomas; Pécoud, Alain; Favrat, Bernard

    2010-02-21

    The intuitive early diagnostic guess could play an important role in reaching a final diagnosis. However, no study to date has attempted to quantify the importance of general practitioners' (GPs) ability to correctly appraise the origin of chest pain within the first minutes of an encounter. The validation study was nested in a multicentre cohort study with a one year follow-up and included 626 successive patients who presented with chest pain and were attended by 58 GPs in Western Switzerland. The early diagnostic guess was assessed prior to a patient's history being taken by a GP and was then compared to a diagnosis of chest pain observed over the next year. Using summary measures clustered at the GP's level, the early diagnostic guess was confirmed by further investigation in 51.0% (CI 95%; 49.4% to 52.5%) of patients presenting with chest pain. The early diagnostic guess was more accurate in patients with a life threatening illness (65.4%; CI 95% 64.5% to 66.3%) and in patients who did not feel anxious (62.9%; CI 95% 62.5% to 63.3%). The predictive abilities of an early diagnostic guess were consistent among GPs. The GPs early diagnostic guess was correct in one out of two patients presenting with chest pain. The probability of a correct guess was higher in patients with a life-threatening illness and in patients not feeling anxious about their pain.

  15. Predictive ability of an early diagnostic guess in patients presenting with chest pain; a longitudinal descriptive study

    Directory of Open Access Journals (Sweden)

    Bischoff Thomas

    2010-02-01

    Full Text Available Abstract Background The intuitive early diagnostic guess could play an important role in reaching a final diagnosis. However, no study to date has attempted to quantify the importance of general practitioners' (GPs ability to correctly appraise the origin of chest pain within the first minutes of an encounter. Methods The validation study was nested in a multicentre cohort study with a one year follow-up and included 626 successive patients who presented with chest pain and were attended by 58 GPs in Western Switzerland. The early diagnostic guess was assessed prior to a patient's history being taken by a GP and was then compared to a diagnosis of chest pain observed over the next year. Results Using summary measures clustered at the GP's level, the early diagnostic guess was confirmed by further investigation in 51.0% (CI 95%; 49.4% to 52.5% of patients presenting with chest pain. The early diagnostic guess was more accurate in patients with a life threatening illness (65.4%; CI 95% 64.5% to 66.3% and in patients who did not feel anxious (62.9%; CI 95% 62.5% to 63.3%. The predictive abilities of an early diagnostic guess were consistent among GPs. Conclusions The GPs early diagnostic guess was correct in one out of two patients presenting with chest pain. The probability of a correct guess was higher in patients with a life-threatening illness and in patients not feeling anxious about their pain.

  16. Innovations in plant health services in Nicaragua

    DEFF Research Database (Denmark)

    Danielsen, Solveig; Centeno, Julio; López, Julio

    2013-01-01

    to the creation of a ‘National Plant Health System’ offering regular advice to farmers. The innovations were driven by a momentum for change, committed individuals, joint learning and flexibility in programme management. External facilitation encouraged experimentation and bolstered growth of new alliances....... The development of the national plant health system was constrained by existing work cultures that limit the scope of individual and institutional innovations.......Establishing a few community-based plant clinics in Nicaragua led to a series of innovations in plant health service delivery. A grassroots experiment became a nationwide initiative involving local service providers, universities, research institutions and diagnostic laboratories. This led...

  17. STARD 2015: An Updated List of Essential Items for Reporting Diagnostic Accuracy Studies

    NARCIS (Netherlands)

    Bossuyt, P.M.; Reitsma, J.B.; Bruns, D.E.; Gatsonis, C.A.; Glasziou, P.P.; Irwig, L.; Lijmer, J.G.; Moher, D.; Rennie, D.; de Vet, H.C.W.; Kressel, H.Y.; Rifai, N.; Golub, R.M.; Altman, D.G.; Hooft, L.; Korevaar, D.A.; Cohen, J.F.

    2015-01-01

    Incomplete reporting has been identified as a major source of avoidable waste in biomedical research. Essential information is often not provided in study reports, impeding the identification, critical appraisal, and replication of studies. To improve the quality of reporting of diagnostic accuracy

  18. Towards complete and accurate reporting of studies of diagnostic accuracy: The STARD initiative

    NARCIS (Netherlands)

    Bossuyt, Patrick M.; Reitsma, Johannes B.; Bruns, David E.; Gatsonis, Constantine A.; Glasziou, Paul P.; Irwig, Les M.; Lijmer, Jeroen G.; Moher, David; Rennie, Drummond; de Vet, Henrica C. W.

    2003-01-01

    Background: To comprehend the results of diagnostic accuracy studies, readers must understand the design, conduct, analysis, and results of such studies. That goal can be achieved only through complete transparency from authors. Objective: To improve the accuracy and completeness of reporting of

  19. Plant-uptake of uranium: Hydroponic and soil system studies

    Science.gov (United States)

    Ramaswami, A.; Carr, P.; Burkhardt, M.

    2001-01-01

    Limited information is available on screening and selection of terrestrial plants for uptake and translocation of uranium from soil. This article evaluates the removal of uranium from water and soil by selected plants, comparing plant performance in hydroponic systems with that in two soil systems (a sandy-loam soil and an organic-rich soil). Plants selected for this study were Sunflower (Helianthus giganteus), Spring Vetch (Vicia sativa), Hairy Vetch (Vicia villosa), Juniper (Juniperus monosperma), Indian Mustard (Brassica juncea), and Bush Bean (Phaseolus nanus). Plant performance was evaluated both in terms of the percent uranium extracted from the three systems, as well as the biological absorption coefficient (BAC) that normalized uranium uptake to plant biomass. Study results indicate that uranium extraction efficiency decreased sharply across hydroponic, sandy and organic soil systems, indicating that soil organic matter sequestered uranium, rendering it largely unavailable for plant uptake. These results indicate that site-specific soils must be used to screen plants for uranium extraction capability; plant behavior in hydroponic systems does not correlate well with that in soil systems. One plant species, Juniper, exhibited consistent uranium extraction efficiencies and BACs in both sandy and organic soils, suggesting unique uranium extraction capabilities.

  20. A unified plant information network

    International Nuclear Information System (INIS)

    Niederauer, G.F.

    1986-01-01

    Technology is bringing power plants fully into the age of computerization. Microcomputers, data base managers, networking, and friendly, expert software are principal technology factors. Monitoring will improve, and the number and power of computers is increasing. The huge information flow will cause computers to be integrated into a communication network. The total plant operating triangle includes process, engineering, and management systems. The total network will integrate all of these into a Total Unified Plant Information Network (TUPIN). Software will take the type of information beyond monitored data. Analysis will improve through direct access to logical, physical, and procedural models by end users. Information management will improve through widespread use of hierarchical, relational, and expert data base managers. Expert systems will aid in diagnostics and interpretation. The goal is to automate plant operations to enhance safety and performance and to reduce cost by making both the plants and the personnel more expert

  1. Artificial intelligence methods for diagnostic

    International Nuclear Information System (INIS)

    Dourgnon-Hanoune, A.; Porcheron, M.; Ricard, B.

    1996-01-01

    To assist in diagnosis of its nuclear power plants, the Research and Development Division of Electricite de France has been developing skills in Artificial Intelligence for about a decade. Different diagnostic expert systems have been designed. Among them, SILEX for control rods cabinet troubleshooting, DIVA for turbine generator diagnosis, DIAPO for reactor coolant pump diagnosis. This know how in expert knowledge modeling and acquisition is direct result of experience gained during developments and of a more general reflection on knowledge based system development. We have been able to reuse this results for other developments such as a guide for auxiliary rotating machines diagnosis. (authors)

  2. Diagnostic accuracy of the Eurotest for dementia: a naturalistic, multicenter phase II study

    Directory of Open Access Journals (Sweden)

    Frank Ana

    2006-04-01

    Full Text Available Abstract Background Available screening tests for dementia are of limited usefulness because they are influenced by the patient's culture and educational level. The Eurotest, an instrument based on the knowledge and handling of money, was designed to overcome these limitations. The objective of this study was to evaluate the diagnostic accuracy of the Eurotest in identifying dementia in customary clinical practice. Methods A cross-sectional, multi-center, naturalistic phase II study was conducted. The Eurotest was administered to consecutive patients, older than 60 years, in general neurology clinics. The patients' condition was classified as dementia or no dementia according to DSM-IV diagnostic criteria. We calculated sensitivity (Sn, specificity (Sp and area under the ROC curves (aROC with 95% confidence intervals. The influence of social and educational factors on scores was evaluated with multiple linear regression analysis, and the influence of these factors on diagnostic accuracy was evaluated with logistic regression. Results Sixteen neurologists recruited a total of 516 participants: 101 with dementia, 380 without dementia, and 35 who were excluded. Of the 481 participants who took the Eurotest, 38.7% were totally or functionally illiterate and 45.5% had received no formal education. Mean time needed to administer the test was 8.2+/-2.0 minutes. The best cut-off point was 20/21, with Sn = 0.91 (0.84–0.96, Sp = 0.82 (0.77–0.85, and aROC = 0.93 (0.91–0.95. Neither the scores on the Eurotest nor its diagnostic accuracy were influenced by social or educational factors. Conclusion This naturalistic and pragmatic study shows that the Eurotest is a rapid, simple and useful screening instrument, which is free from educational influences, and has appropriate internal and external validity.

  3. Development of new diagnostics for WEST

    International Nuclear Information System (INIS)

    Lotte, P.; Moreau, P.; Gil, C.

    2015-01-01

    WEST, the upgraded superconducting tokamak Tore Supra, will be an international experimental platform aimed to support ITER Physics program. The main objective of WEST is to provide relevant plasma conditions for validating plasma facing component (PFC) technology, in particular the actively cooled Tungsten divertor monoblocks, and also assessing high heat flux and high fluence plasma wall interactions with Tungsten in order to prepare ITER divertor operation. In parallel, WEST will also open new experimental opportunities for developing integrated H mode operation and exploring steady state scenarios in a metallic environment. In order to fulfil the Scientific Program of WEST, new diagnostics have been developed in addition to the already existing diagnostics of Tore Supra, modified and improved during the shutdown. For the PFC technology validation program, new tools have been implemented, like a full infrared survey of the PFC, a new calorimetry system, local temperature measurements (thermocouple and Bragg grating optical fiber), and several sets of Langmuir probes. For the analysis of long pulse H mode operation, new plasma diagnostics will be implemented, among which the Visible Spectroscopy diagnostic for W sources and transport studies, the Soft-Xray diagnostic based on gas electron multiplier detectors for transport and MHD studies, the X-ray imaging crystal spectroscopy diagnostic with advanced solid state detector properties for ion temperature, ion density and plasma rotation velocity measurements, and the ECE Imaging diagnostic for MHD and turbulence studies. Most of these new diagnostics are developed with the participation of French Universities or through international collaborations. This paper focuses on the description of these four plasma diagnostics. (author)

  4. A study on the efficiency improvement of the plant secondary System in NPP

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Chun Ho; Song Jong Sun [Chosun Univ., Kwangju (Korea, Republic of)

    2012-10-15

    The ultimate objective of the diagnostic test for thermal performance of generation facilities is to assist in making an economic decision on operation optimization of power plants by understanding the degree of heat aging due to operation of relevant facilities and planning on this basis the maintenance and repair. In this thesis, the trend in performance change was analyzed against the acceptance performance test conducted after the replacement of the high pressure turbine in 2007, through thermal performance diagnosis conducted at 100 % reactor thermal output after the 19th planned preventive maintenance of Yonggwang Nuclear Units 1 and 2, and the power plant operation was optimized by acquiring base line data for management of performance record for each major facility of the secondary system and by improving efficiency of unit instruments and peripheral instruments of the secondary system. As a result derived from the thermal performance analysis, the increase in electric output of the power plants was achieved through such operation optimizations of efficiency affecting instruments as optimization of the continuous exhaust flow rate for water supply heaters, vacuum improvement of condensers due to opening the upper/lower screens of heat transfer pipe washing system for condensers during summer, and flow rate optimization of the water vapor supplied to MSR (Moisture Separator Re heater) high pressure re heaters. This improves operation of the existing power plants without additional expense and so requires expert review by responsible personnel for practical application.

  5. Psychologists' diagnostic processes during a diagnostic interview

    NARCIS (Netherlands)

    Groenier, Marleen; Beerthuis, Vos R.J.; Pieters, Julius Marie; Witteman, C.L.M.; Witteman, Cilia L.M.; Swinkels, Jan A.

    2011-01-01

    In mental health care, psychologists assess clients’ complaints, analyze underlying problems, and identify causes for these problems, to make treatment decisions. We present a study on psychologists’ diagnostic processes, in which a mixed-method approach was employed. We aimed to identify a common

  6. Multisite Study of New Autism Diagnostic Interview-Revised (ADI-R) Algorithms for Toddlers and Young Preschoolers

    Science.gov (United States)

    Kim, So Hyun; Thurm, Audrey; Shumway, Stacy; Lord, Catherine

    2013-01-01

    Using two independent datasets provided by National Institute of Health funded consortia, the Collaborative Programs for Excellence in Autism and Studies to Advance Autism Research and Treatment (n = 641) and the National Institute of Mental Health (n = 167), diagnostic validity and factor structure of the new Autism Diagnostic Interview (ADI-R)…

  7. Network meta-analysis of diagnostic test accuracy studies identifies and ranks the optimal diagnostic tests and thresholds for health care policy and decision-making.

    Science.gov (United States)

    Owen, Rhiannon K; Cooper, Nicola J; Quinn, Terence J; Lees, Rosalind; Sutton, Alex J

    2018-07-01

    Network meta-analyses (NMA) have extensively been used to compare the effectiveness of multiple interventions for health care policy and decision-making. However, methods for evaluating the performance of multiple diagnostic tests are less established. In a decision-making context, we are often interested in comparing and ranking the performance of multiple diagnostic tests, at varying levels of test thresholds, in one simultaneous analysis. Motivated by an example of cognitive impairment diagnosis following stroke, we synthesized data from 13 studies assessing the efficiency of two diagnostic tests: Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA), at two test thresholds: MMSE accounting for the correlations between multiple test accuracy measures from the same study. We developed and successfully fitted a model comparing multiple tests/threshold combinations while imposing threshold constraints. Using this model, we found that MoCA at threshold decision making. Copyright © 2018 The Authors. Published by Elsevier Inc. All rights reserved.

  8. Integrating Studies on Plant-Pollinator and Plant-Herbivore Interactions

    NARCIS (Netherlands)

    Lucas-Barbosa, Dani

    2016-01-01

    Research on herbivore-induced plant defence and research on pollination ecology have had a long history of separation. Plant reproduction of most angiosperm species is mediated by pollinators, and the effects of herbivore-induced plant defences on pollinator behaviour have been largely neglected.

  9. Assessing the Utility of Diagnostic Criteria: A Multisite Study on Gender Identity Disorder

    NARCIS (Netherlands)

    Paap, M.C.S.; Kreukels, B.P.C.; Cohen-Kettenis, P.T.; Richter-Appelt, H.; De Cuypere, G.; Haraldsen, I.R.

    2011-01-01

    Studies involving patients with gender identity disorder (GID) are inconsistent with regard to outcomes and often difficult to compare because of the vague descriptions of the diagnostic process. A multisite study is needed to scrutinize the utility and generality of different aspects of the

  10. Consensus based reporting standards for diagnostic test accuracy studies for paratuberculosis in ruminants.

    NARCIS (Netherlands)

    Gardner, I.A.; Nielsen, S.S.; Whittington, R.J.; Collins, M.T.; Bakker, D.; Harris, B.; Sreevatsan, S.; Lombard, J.E.; Sweeney, R.; Smith, D.R.; Gavalchin, J.; Eda, S.

    2011-01-01

    The Standards for Reporting of Diagnostic Accuracy (STARD) statement (www.stard-statement.org) was developed to encourage complete and transparent reporting of key elements of test accuracy studies in human medicine. The statement was motivated by widespread evidence of bias in test accuracy studies

  11. A diagnosis of bipolar spectrum disorder predicts diagnostic conversion from unipolar depression to bipolar disorder: a 5-year retrospective study.

    Science.gov (United States)

    Woo, Young Sup; Shim, In Hee; Wang, Hee-Ryung; Song, Hoo Rim; Jun, Tae-Youn; Bahk, Won-Myong

    2015-03-15

    The major aims of this study were to identify factors that may predict the diagnostic conversion from major depressive disorder (MDD) to bipolar disorder (BP) and to evaluate the predictive performance of the bipolar spectrum disorder (BPSD) diagnostic criteria. The medical records of 250 patients with a diagnosis of MDD for at least 5 years were retrospectively reviewed for this study. The diagnostic conversion from MDD to BP was observed in 18.4% of 250 MDD patients, and the diagnostic criteria for BPSD predicted this conversion with high sensitivity (0.870) and specificity (0.917). A family history of BP, antidepressant-induced mania/hypomania, brief major depressive episodes, early age of onset, antidepressant wear-off, and antidepressant resistance were also independent predictors of this conversion. This study was conducted using a retrospective design and did not include structured diagnostic interviews. The diagnostic criteria for BPSD were highly predictive of the conversion from MDD to BP, and conversion was associated with several clinical features of BPSD. Thus, the BPSD diagnostic criteria may be useful for the prediction of bipolar diathesis in MDD patients. Copyright © 2014 Elsevier B.V. All rights reserved.

  12. Development of reactor accident diagnostic system DISKET using knowledge engineering technique

    International Nuclear Information System (INIS)

    Yokobayashi, Masao; Yoshida, Kazuo; Kohsaka, Atsuo; Yamamoto, Minoru.

    1986-01-01

    An accident diagnostic system DISKET has been developed to identify the cause and the type of an abnormal transient of a nuclear power plant. The system is based on the knowledge engineering (KE) and consists of an inference engine IERIAS and a knowledge base. The main features of DISKET are the following : (1) Time-varying characteristics of transients can be treated. (2) Knowledge base can be divided into several knowledge units to handle a lot of rules effectively. (3) Programming language UTILISP, which is a dialect of LISP, is used to manipulate symbolic data effectively. For the verification of DISKET, performance tests have been conducted for several types of accidents. The knowledge base used in the tests was generated from the data of various types of transients produced by a PWR plant simulator. The results of verification studies showed a good applicability of DISKET to reactor accident diagnosis. (author)

  13. Use of expert systems in nuclear power plants

    International Nuclear Information System (INIS)

    Uhrig, R.E.

    1989-01-01

    The application of technologies, particularly expert systems, to the control room activities in a nuclear power plant has the potential to reduce operator error and increase plant safety, reliability, and efficiency. Furthermore, there are a large number of nonoperating activities (testing, routine maintenance, outage planning, equipment diagnostics, and fuel management) in which expert systems can increase the efficiency and effectiveness of overall plant and corporate operations. This document presents a number of potential applications of expert systems in the nuclear power field. 36 refs., 2 tabs

  14. Antisense oligodeoxynucleotide inhibition as a potent diagnostic tool for gene function in plant biology

    Energy Technology Data Exchange (ETDEWEB)

    Jansson, Christer; Sun, Chuanxin; Ghebramedhin, Haile; Hoglund, Anna-Stina; Jansson, Christer

    2008-01-15

    Antisense oligodeoxynucleotide (ODN) inhibition emerges as an effective means for probing gene function in plant cells. Employing this method we have established the importance of the SUSIBA2 transcription factor for regulation of starch synthesis in barley endosperm, and arrived at a model for the role of the SUSIBAs in sugar signaling and source-sink commutation during cereal endosperm development. In this addendum we provide additional data demonstrating the suitability of the antisense ODN technology in studies on starch branching enzyme activities in barley leaves. We also comment on the mechanism for ODN uptake in plant cells. Antisense ODNs are short (12-25 nt-long) stretches of single-stranded ODNs that hybridize to the cognate mRNA in a sequence-specific manner, thereby inhibiting gene expression. They are naturally occurring in both prokaryotes and eukaryotes where they partake in gene regulation and defense against viral infection. The mechanisms for antisense ODN inhibition are not fully understood but it is generally considered that the ODN either sterically interferes with translation or promotes transcript degradation by RNase H activation. The earliest indication of the usefulness of antisense ODN technology for the purposes of molecular biology and medical therapy was the demonstration in 1978 that synthetic ODNs complementary to Raos sarcoma virus could inhibit virus replication in tissue cultures of chick embryo fibroblasts. Since then the antisense ODN technology has been widely used in animal sciences and as an important emerging therapeutic approach in clinical medicine. However, antisense ODN inhibition has been an under-exploited strategy for plant tissues, although the prospects for plant cells in suspension cultures to take up single-stranded ODNs was reported over a decade ago. In 2001, two reports from Malho and coworker demonstrated the use of cationic-complexed antisense ODNs to suppress expression of genes encoding pollen

  15. The prediction of the LWR plant accident based on the measured plant data

    International Nuclear Information System (INIS)

    Miettinen, J.; Schmuck, P.

    2005-01-01

    In case of accident affecting a nuclear reactor, it is essential to anticipate the possible development of the situation to efficiently succeed in emergency response actions, i.e. firstly to be early warned, to get sufficient information on the plant: and as far as possible. The ASTRID (Assessment of Source Term for Emergency Response based on Installation Data) project consists in developing a methodology: of expertise to; structure the work of technical teams and to facilitate cross competence communications among EP players and a qualified computer tool that could be commonly used by the European countries to reliably predict source term in case of an accident in a light water reactor, using the information available on the plant. In many accident conditions the team of analysts may be located far away from the plant experiencing the accident and their decision making is based on the on-line plant data transmitted into the crisis centre in an interval of 30 - 600 seconds. The plant condition has to be diagnosed based on this information, In the ASTRID project the plant status diagnostics has been studied for the European reactor types including BWR, PWR and VVER plants. The directly measured plant data may be used for estimations of the break size from the primary system and its locations. The break size prediction may be based on the pressurizer level, reactor vessel level, primary pressure and steam generator level in the case of the steam generator tube rupture. In the ASTRID project the break predictions concept was developed and its validity for different plant types and is presented in the paper, when the plant data has been created with the plant specific thermohydraulic simulation model. The tracking simulator attempts to follow the plant behavior on-line based on the measured plant data for the main process parameters and most important boundary conditions. When the plant state tracking fails, the plant may be experiencing an accident, and the tracking

  16. Advances in molecular-based diagnostics in meeting crop biosecurity and phytosanitary issues.

    Science.gov (United States)

    Schaad, Norman W; Frederick, Reid D; Shaw, Joe; Schneider, William L; Hickson, Robert; Petrillo, Michael D; Luster, Douglas G

    2003-01-01

    Awareness of crop biosecurity and phytosanitation has been heightened since 9/11 and the unresolved anthrax releases in October 2001. Crops are highly vulnerable to accidental or deliberate introductions of crop pathogens from outside U.S. borders. Strategic thinking about protection against deliberate or accidental release of a plant pathogen is an urgent priority. Rapid detection will be the key to success. This review summarizes recent progress in the development of rapid real-time PCR protocols and evaluates their effectiveness in a proposed nationwide network of diagnostic laboratories that will facilitate rapid diagnostics and improved communication.

  17. Childhood leukemia near nuclear plants in the United Kingdom: The evolution of a systematic approach to studying rare disease in small geographic areas

    International Nuclear Information System (INIS)

    Beral, V.

    1990-01-01

    A cluster of childhood leukemia in a village near a nuclear plant in northern England prompted further studies of cancer in the vicinity of other nuclear plants in the United Kingdom. These studies demonstrated that the risk of childhood leukemia was increased near certain other nuclear plants. Although the reasons for the increase are still unclear, the scientific debate stimulated by these findings has clarified some of the special methodological problems encountered when studying rare diseases in small areas. Firstly, unless a specific hypothesis is defined in advance, the relevance of a single geographic cluster of disease can rarely be interpreted. Even when a prior hypothesis exists, the small number of cases which generally occur in a small area make the findings highly sensitive to reporting, diagnostic, or classification errors. The statistical power of such investigations is also usually low and only marked increases in risk can be detected. Furthermore, conventional statistical tests may be inappropriate if the underlying spatial distribution of the disease is not random; and little is known about the background distribution of disease in small areas. Investigations of specific hypotheses about defined sources of environmental contamination, especially if they can be replicated, are more likely to result in conclusive findings that are in-depth studies of individual clusters

  18. Portuguese Family Physicians' Awareness of Diagnostic and Laboratory Test Costs: A Cross-Sectional Study.

    Directory of Open Access Journals (Sweden)

    Luísa Sá

    Full Text Available Physicians' ability to make cost-effective decisions has been shown to be affected by their knowledge of health care costs. This study assessed whether Portuguese family physicians are aware of the costs of the most frequently prescribed diagnostic and laboratory tests.A cross-sectional study was conducted in a representative sample of Portuguese family physicians, using computer-assisted telephone interviews for data collection. A Likert scale was used to assess physician's level of agreement with four statements about health care costs. Family physicians were also asked to estimate the costs of diagnostic and laboratory tests. Each physician's cost estimate was compared with the true cost and the absolute error was calculated.One-quarter (24%; 95% confidence interval: 23%-25% of all cost estimates were accurate to within 25% of the true cost, with 55% (95% IC: 53-56 overestimating and 21% (95% IC: 20-22 underestimating the true actual cost. The majority (76% of family physicians thought they did not have or were uncertain as to whether they had adequate knowledge of diagnostic and laboratory test costs, and only 7% reported receiving adequate education. The majority of the family physicians (82% said that they had adequate access to information about the diagnostic and laboratory test costs. Thirty-three percent thought that costs did not influence their decision to order tests, while 27% were uncertain.Portuguese family physicians have limited awareness of diagnostic and laboratory test costs, and our results demonstrate a need for improved education in this area. Further research should focus on identifying whether interventions in cost knowledge actually change ordering behavior, in identifying optimal methods to disseminate cost information, and on improving the cost-effectiveness of care.

  19. Portuguese Family Physicians’ Awareness of Diagnostic and Laboratory Test Costs: A Cross-Sectional Study

    Science.gov (United States)

    Sá, Luísa; Costa-Santos, Cristina; Teixeira, Andreia; Couto, Luciana; Costa-Pereira, Altamiro; Hespanhol, Alberto; Santos, Paulo; Martins, Carlos

    2015-01-01

    Background Physicians’ ability to make cost-effective decisions has been shown to be affected by their knowledge of health care costs. This study assessed whether Portuguese family physicians are aware of the costs of the most frequently prescribed diagnostic and laboratory tests. Methods A cross-sectional study was conducted in a representative sample of Portuguese family physicians, using computer-assisted telephone interviews for data collection. A Likert scale was used to assess physician’s level of agreement with four statements about health care costs. Family physicians were also asked to estimate the costs of diagnostic and laboratory tests. Each physician’s cost estimate was compared with the true cost and the absolute error was calculated. Results One-quarter (24%; 95% confidence interval: 23%–25%) of all cost estimates were accurate to within 25% of the true cost, with 55% (95% IC: 53–56) overestimating and 21% (95% IC: 20–22) underestimating the true actual cost. The majority (76%) of family physicians thought they did not have or were uncertain as to whether they had adequate knowledge of diagnostic and laboratory test costs, and only 7% reported receiving adequate education. The majority of the family physicians (82%) said that they had adequate access to information about the diagnostic and laboratory test costs. Thirty-three percent thought that costs did not influence their decision to order tests, while 27% were uncertain. Conclusions Portuguese family physicians have limited awareness of diagnostic and laboratory test costs, and our results demonstrate a need for improved education in this area. Further research should focus on identifying whether interventions in cost knowledge actually change ordering behavior, in identifying optimal methods to disseminate cost information, and on improving the cost-effectiveness of care. PMID:26356625

  20. Some causes of vibrations recorded by in-service diagnostic systems in steam generators of units 1 and 2 of Dukovany nuclear power plant

    International Nuclear Information System (INIS)

    Sadilek, J.; Matal, O.

    1989-01-01

    A brief description is presented of the design of the steam generators of the first and second units of the Dukovany nuclear power plant. Attention is also given to the feed water systems and the diagnostic systems. The causes are analyzed of the irregularly occurring vibrations in the steam generators in service. It is demonstrated that the source of the vibrations transmitted to the steam generators are the valves in the feeding tract. The vibrations are induced by dynamic forces from the feed water. Reducing the water pressure at the delivery of the electric feed pumps by reducing the size of the rotor, etc., does not remove all vibrations. It is therefore recommended that valves be ins+alled with better regulating characteristics. (Z.M.). 6 figs., 1 tab., 3 refs

  1. Intelligent monitoring of water chemistry - Diagnostic expert system DIWATM

    International Nuclear Information System (INIS)

    Metzner, W.; Streit, K.

    2002-01-01

    For fast and comprehensive evaluation of power plant water chemistry conditions and reliable diagnosis in the event of disturbances considerable advantages are provided by employment of the Diagnostic Expert System DIWA. The interface to the process control system (I and C) and the integration of the DIWA system in the office PC network are the preconditions that DIWA operates as a monitoring system in real time. The performance of diagnosis, which are processed by a fuzzy-logic-supported knowledge base ensures not only the detection of all disturbances but also different analyses of the plant operation mode. By editing the knowledge base the Al of the system can increase without system programming. (authors)

  2. Plant air systems safety study: Portsmouth Gaseous Diffusion Plant

    International Nuclear Information System (INIS)

    1982-05-01

    The Portsmouth Gaseous Diffusion Plant Air System facilities and operations are reviewed for potential safety problems not covered by standard industrial safety procedures. Information is presented under the following section headings: facility and process description (general); air plant equipment; air distribution system; safety systems; accident analysis; plant air system safety overview; and conclusion

  3. LHD neutron diagnostics

    International Nuclear Information System (INIS)

    Isobe, M.; Ogawa, K.; Kobuchi, T.

    2015-01-01

    The Large Helical Device (LHD) project will step into a next stage, i.e. experiment by using deuterium gases after two years of preparation. A comprehensive set of neutron and γ-ray diagnostics is going to be installed on the LHD towards extension of energetic-particle (EP) physics research in heliotron plasmas. Conceptual design of fusion products diagnostics for the LHD was made in late 1990s. After conclusion of agreements for the LHD deuterium experiment with local government bodies, development of FPs diagnostics has begun lately. Because there are a lot of tasks to do, all Japan fusion neutron and γ-ray diagnostics team has been organized in the collaboration framework of National Institute for Fusion Science. FPs diagnostics system on the LHD will consist of 1) wide dynamic range neutron flux monitor (NFM), 2) neutron activation system (NAS), 3) vertical neutron camera (VNC). In addition to these, we are developing a directional scintillating fiber detector, an artificial diamond detector and a γ-ray scintillation detector for confinement study of MeV ions. A neutron energy spectrometer prototype is also being developed and tested in KSTAR. In this paper, roles of NFM, NAS and VNC and current status of implementation onto the LHD are briefly described. (author)

  4. Diagnostic value of tumor markers for lung adenocarcinoma-associated malignant pleural effusion: a validation study and meta-analysis.

    Science.gov (United States)

    Feng, Mei; Zhu, Jing; Liang, Liqun; Zeng, Ni; Wu, Yanqiu; Wan, Chun; Shen, Yongchun; Wen, Fuqiang

    2017-04-01

    Pleural effusion is one of the most common complications of lung adenocarcinoma and is diagnostically challenging. This study aimed to investigate the diagnostic performance of carcinoembryonic antigen (CEA), cytokeratin fragment (CYFRA) 21-1, and cancer antigen (CA) 19-9 for lung adenocarcinoma-associated malignant pleural effusion (MPE) through a validation study and meta-analysis. Pleural effusion samples were collected from 81 lung adenocarcinoma-associated MPEs and 96 benign pleural effusions. CEA, CYFRA 21-1, and CA19-9 were measured by electrochemiluminescence immunoassay. The capacity of tumor markers was assessed with receiver operating characteristic curve analyses and the area under the curve (AUC) was calculated. Standard methods for meta-analysis of diagnostic studies were used to summarize the diagnostic performance of CEA, CYFRA 21-1, and CA19-9 for lung adenocarcinoma-associated MPE. The pleural levels of CEA, CYFRA 21-1, and CA19-9 were significantly increased in lung adenocarcinoma-associated MPE compared to benign pleural effusion. The cut-off points for CEA, CYFRA 21-1, and CA19-9 were optimally set at 4.55 ng/ml, 43.10 μg/ml, and 12.89 U/ml, and corresponding AUCs were 0.93, 0.85, and 0.81, respectively. The combination of CEA, CYFRA 21-1, and CA19-9 increased the sensitivity to 95.06%, with an AUC of 0.95. Eight studies were included in this meta-analysis. CEA showed the best diagnostic performance with pooled sensitivity, specificity, positive/negative likelihood ratio, and diagnostic odds ratio of 0.75, 0.96, 16.01, 0.23, and 81.49, respectively. The AUC was 0.93. CEA, CYFRA 21-1, and CA19-9 play a role in the diagnosis of lung adenocarcinoma-associated MPE. The combination of these tumor markers increases the diagnostic accuracy.

  5. Real time water chemistry monitoring and diagnostics

    International Nuclear Information System (INIS)

    Gaudreau, T.M.; Choi, S.S.

    2002-01-01

    EPRI has produced a real time water chemistry monitoring and diagnostic system. This system is called SMART ChemWorks and is based on the EPRI ChemWorks codes. System models, chemistry parameter relationships and diagnostic approaches from these codes are integrated with real time data collection, an intelligence engine and Internet technologies to allow for automated analysis of system chemistry. Significant data management capabilities are also included which allow the user to evaluate data and create automated reporting. Additional features have been added to the system in recent years including tracking and evaluation of primary chemistry as well as the calculation and tracking of primary to secondary leakage in PWRs. This system performs virtual sensing, identifies normal and upset conditions, and evaluates the consistency of on-line monitor and grab sample readings. The system also makes use of virtual fingerprinting to identify the cause of any chemistry upsets. This technology employs plant-specific data and models to determine the chemical state of the steam cycle. (authors)

  6. Diagnostic shift in patients diagnosed with schizoaffective disorder: a systematic review and meta-analysis of rediagnosis studies.

    Science.gov (United States)

    Santelmann, Hanno; Franklin, Jeremy; Bußhoff, Jana; Baethge, Christopher

    2016-05-01

    The diagnosis of schizoaffective disorder (SAD) is well established in clinical practice but is heavily disputed on theoretical grounds. We analyzed the extent and direction of diagnostic shift in SAD patients. We searched Medline, Embase, and PsycINFO systematically for all studies documenting two diagnostic assessments at different points in time (rediagnosis studies) and used meta-analytic methods to quantify diagnostic shift. Multiple prespecified and post-hoc subgroup analyses (e.g., rater blinding) and meta-regressions (e.g., year of publication) were carried out. We included 31 studies out of 4,415 articles screened: 27 studies on the shift from and 23 studies on the shift to SAD (median time span was two years). A total of 36% of patients with a diagnosis of SAD at first assessment switch, many to schizophrenia (19%), 14% to affective disorders, and 6% to other disorders. Among patients diagnosed with SAD at second assessment, 55% had received a different diagnosis at first assessment, a large portion of whom had been initially diagnosed with affective disorder (24%), schizophrenia (18%), and other disorders (12%). Diagnostic shift in SAD patients is substantial. Psychiatrists need to reassess the diagnosis during the course of the illness and to adjust treatment. Slightly more diagnoses of SAD are changed to schizophrenia than to affective disorders, and among patients rediagnosed with SAD, fewer have been diagnosed with schizophrenia than with affective disorders. Thus, at the diagnostic level, there seems to be a slight trend toward schizophrenia during the course of functional psychoses. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  7. Diagnostic and laboratory test ordering in Northern Portuguese Primary Health Care: a cross-sectional study

    Science.gov (United States)

    Sá, Luísa; Teixeira, Andreia Sofia Costa; Tavares, Fernando; Costa-Santos, Cristina; Couto, Luciana; Costa-Pereira, Altamiro; Hespanhol, Alberto Pinto; Santos, Paulo

    2017-01-01

    Objectives To characterise the test ordering pattern in Northern Portugal and to investigate the influence of context-related factors, analysing the test ordered at the level of geographical groups of family physicians and at the level of different healthcare organisations. Design Cross-sectional study. Setting Northern Primary Health Care, Portugal. Participants Records about diagnostic and laboratory tests ordered from 2035 family physicians working at the Northern Regional Health Administration, who served approximately 3.5 million Portuguese patients, in 2014. Outcomes To determine the 20 most ordered diagnostic and laboratory tests in the Northern Regional Health Administration; to identify the presence and extent of variations in the 20 most ordered diagnostic and laboratory tests between the Groups of Primary Care Centres and between health units; and to study factors that may explain these variations. Results The 20 most ordered diagnostic and laboratory tests almost entirely comprise laboratory tests and account for 70.9% of the total tests requested. We can trace a major pattern of test ordering for haemogram, glucose, lipid profile, creatinine and urinalysis. There was a significant difference (P<0.001) in test orders for all tests between Groups of Primary Care Centres and for all tests, except glycated haemoglobin (P=0.06), between health units. Generally, the Personalised Healthcare Units ordered more than Family Health Units. Conclusions The results from this study show that the most commonly ordered tests in Portugal are laboratory tests, that there is a tendency for overtesting and that there is a large variability in diagnostic and laboratory test ordering in different geographical and organisational Portuguese primary care practices, suggesting that there may be considerable potential for the rationalisation of test ordering. The existence of Family Health Units seems to be a strong determinant in decreasing test ordering by Portuguese family

  8. Study on VDI-2048 for Plant Efficiency Calculation

    International Nuclear Information System (INIS)

    Lee, Hanseol; Heo, Gyunyoung

    2014-01-01

    It is a representative example when main steam mass flow of a steam generator is measured lower than main feedwater mass flow of outlet, or when efficiency of low pressure turbine is analyzed excessively low or exceeds 100 percent. Therefore, we need to obtain measured data minimizing uncertainty to calculate thermal efficiency as exactly as possible. In calculating the efficiency of an Nuclear Power Plant(NPP), measurement uncertainty is the most difficult to be solved technically and data reconciliation methodology is one method of ensuring to minimize uncertainty. In this paper, the case study on previous nuclear power plants was carried out by using redundancy of measured data from measuring instrument for plant operation, so as to calculate nuclear power plant efficiency accurately. As explain above, we performed the case study on data reconciliation methodology by using measurement redundancy and physical redundancy. The former comes up because of installing multiple measuring instruments for plant operation, and the latter is acquired based on the physical association like the first law of thermodynamics (the law of conservation of mass and energy). Through this case study, we got the reconciled data, which satisfies the constraint and minimizes data uncertainty measured in the nuclear power plant secondary system at the same time. The expected effects from data reconciliation methodology provided in VDI-2048, are considered totally four. First, this method can contribute to monitoring on-line efficiency in the operating nuclear power plant. Second, it can also improve the reliability of calculated results, minimizing the measurement uncertainty

  9. A novel diagnostic aid for intra-abdominal adhesion detection in cine-MR imaging: Pilot study and initial diagnostic impressions.

    Science.gov (United States)

    Randall, David; Joosten, Frank; ten Broek, Richard; Gillott, Richard; Bardhan, Karna Dev; Strik, Chema; Prins, Wiesje; van Goor, Harry; Fenner, John

    2017-07-14

    A non-invasive diagnostic technique for abdominal adhesions is not currently available. Capture of abdominal motion due to respiration in cine-MRI has shown promise, but is difficult to interpret. This article explores the value of a complimentary diagnostic aid to facilitate the non-invasive detection of abdominal adhesions using cine-MRI. An image processing technique was developed to quantify the amount of sliding that occurs between the organs of the abdomen and the abdominal wall in sagittal cine-MRI slices. The technique produces a 'sheargram' which depicts the amount of sliding which has occurred over 1-3 respiratory cycles. A retrospective cohort of 52 patients, scanned for suspected adhesions, made 281 cine-MRI sagittal slices available for processing. The resulting sheargrams were reported by two operators and compared to expert clinical judgement of the cine-MRI scans. The sheargram matched clinical judgement in 84% of all sagittal slices and 93-96% of positive adhesions were identified on the sheargram. The sheargram displayed a slight skew towards sensitivity over specificity, with a high positive adhesion detection rate but at the expense of false positives. Good correlation between sheargram and absence/presence of inferred adhesions indicates quantification of sliding motion has potential to aid adhesion detection in cine-MRI. Advances in Knowledge: This is the first attempt to clinically evaluate a novel image processing technique quantifying the sliding motion of the abdominal contents against the abdominal wall. The results of this pilot study reveal its potential as a diagnostic aid for detection of abdominal adhesions.

  10. Cervical vertebral maturation method and mandibular growth peak: a longitudinal study of diagnostic reliability.

    Science.gov (United States)

    Perinetti, Giuseppe; Primozic, Jasmina; Sharma, Bhavna; Cioffi, Iacopo; Contardo, Luca

    2018-03-28

    The capability of the cervical vertebral maturation (CVM) method in the identification of the mandibular growth peak on an individual basis remains undetermined. The diagnostic reliability of the six-stage CVM method in the identification of the mandibular growth peak was thus investigated. From the files of the Oregon and Burlington Growth Studies (data obtained between early 1950s and middle 1970s), 50 subjects (26 females, 24 males) with at least seven annual lateral cephalograms taken from 9 to 16 years were identified. Cervical vertebral maturation was assessed according to the CVM code staging system, and mandibular growth was defined as annual increments in Co-Gn distance. A diagnostic reliability analysis was carried out to establish the capability of the circumpubertal CVM stages 2, 3, and 4 in the identification of the imminent mandibular growth peak. Variable durations of each of the CVM stages 2, 3, and 4 were seen. The overall diagnostic accuracy values for the CVM stages 2, 3, and 4 were 0.70, 0.76, and 0.77, respectively. These low values appeared to be due to false positive cases. Secular trends in conjunction with the use of a discrete staging system. In most of the Burlington Growth Study sample, the lateral head film at age 15 was missing. None of the CVM stages 2, 3, and 4 reached a satisfactorily diagnostic reliability in the identification of imminent mandibular growth peak.

  11. A Meta-Analysis of Typhoid Diagnostic Accuracy Studies: A Recommendation to Adopt a Standardized Composite Reference.

    Directory of Open Access Journals (Sweden)

    Helen L Storey

    Full Text Available Novel typhoid diagnostics currently under development have the potential to improve clinical care, surveillance, and the disease burden estimates that support vaccine introduction. Blood culture is most often used as the reference method to evaluate the accuracy of new typhoid tests; however, it is recognized to be an imperfect gold standard. If no single gold standard test exists, use of a composite reference standard (CRS can improve estimation of diagnostic accuracy. Numerous studies have used a CRS to evaluate new typhoid diagnostics; however, there is no consensus on an appropriate CRS. In order to evaluate existing tests for use as a reference test or inclusion in a CRS, we performed a systematic review of the typhoid literature to include all index/reference test combinations observed. We described the landscape of comparisons performed, showed results of a meta-analysis on the accuracy of the more common combinations, and evaluated sources of variability based on study quality. This wide-ranging meta-analysis suggests that no single test has sufficiently good performance but some existing diagnostics may be useful as part of a CRS. Additionally, based on findings from the meta-analysis and a constructed numerical example demonstrating the use of CRS, we proposed necessary criteria and potential components of a typhoid CRS to guide future recommendations. Agreement and adoption by all investigators of a standardized CRS is requisite, and would improve comparison of new diagnostics across independent studies, leading to the identification of a better reference test and improved confidence in prevalence estimates.

  12. Efficient diagnostic methods for nuclear power plant monitoring

    International Nuclear Information System (INIS)

    Sunder, R.

    1997-01-01

    There are systems for operational monitoring of vibrations, valves, solid-borne sound, leaks, and embrittlement. The paper focuses on vibration monitoring of pressurized components and systems in PWRs and BWRs. Other than with conventional systems, the task is not to globally monitor the vibration level, but the frequency-selective information is used as a sensitive information source, the level of vibrations being of secondary significance. The essential feature therefore is the comprehensive and selective scanning of individual frequency components in the recorded vibration spectra, which in some cases can be less than a millesimal millimeter. Upon identification of the various vibration components - from so-called baseline analyses using correlation methods - vibration analysis is done by only one step, comparing a defined reference state with the actual vibration state of the monitored system component. In the event of detected deviations, information on the causes of vibrations - essentially component-related structural resonances - will give the relevant cause-effect relationship. The paper uses some practical examples to illustrate that reliable diagnoses are achieved by the above-mentioned frequency-selective technique. It is important, however, to carry out a sufficiently reliable statistical verification of diagnostic data by means of vibration trending. This is ensured with the digital systems and their high data acquisition rates. (orig./CB) [de

  13. Diagnostic systems developed in NPPRI (VUJE) Trnava Inc. for NPPs

    International Nuclear Information System (INIS)

    Kucharek, P.

    1998-01-01

    Since foundation of Nuclear Power Plant Research Institute (NPPRI) in 1977, the department of diagnostics has been dealt with problems related to the theoretical, practical and organizatory questions of operational diagnostics connected with PWR type nuclear components. This department acts directly in locality of NPP Jaslovske Bohunice, but there are performances for all NPP in Slovak or Czech Republic (Dukovany, Mochovce, and Temelin). Besides direct services and achievements for NPP there exist advisory, experts and research activities for the government and supervising authorities, too. In 1985, NPPRI began systematically construct and verify technical means for operational diagnostics of main circulating pumps (MCP) with good results, based on own rich practical experiences and contacts with organisations abroad. In recent years NPPRI as one of recognised qualified and authorised institutions in Slovak Republic has begun to develop a new generation of diagnostic systems for NPP on high technical level but with lower procuring costs in comparison with western countries products. This contribution deals with four following types of diagnostic systems which were not only developed but also delivered and installed on Slovak and Czech nuclear units: - Loose part monitoring system (LPMS), - Humidity monitoring system (HUMON), - Reactor coolant pumps monitoring system (RCPMS), - Primary circuit vibration monitoring system (VMS). Main features of new generation from middle of 1990's of these systems are described in this paper and operational experiences with them too. (author)

  14. Visualization study of operators' plant knowledge model

    International Nuclear Information System (INIS)

    Kanno, Tarou; Furuta, Kazuo; Yoshikawa, Shinji

    1999-03-01

    Nuclear plants are typically very complicated systems and are required extremely high level safety on the operations. Since it is never possible to include all the possible anomaly scenarios in education/training curriculum, plant knowledge formation is desired for operators to enable thein to act against unexpected anomalies based on knowledge base decision making. The authors have been conducted a study on operators' plant knowledge model for the purpose of supporting operators' effort in forming this kind of plant knowledge. In this report, an integrated plant knowledge model consisting of configuration space, causality space, goal space and status space is proposed. The authors examined appropriateness of this model and developed a prototype system to support knowledge formation by visualizing the operators' knowledge model and decision making process in knowledge-based actions with this model on a software system. Finally the feasibility of this prototype as a supportive method in operator education/training to enhance operators' ability in knowledge-based performance has been evaluated. (author)

  15. 9 CFR 145.15 - Diagnostic surveillance program for low pathogenic avian influenza.

    Science.gov (United States)

    2010-01-01

    ... low pathogenic avian influenza. 145.15 Section 145.15 Animals and Animal Products ANIMAL AND PLANT... pathogenic avian influenza. (a) The Official State Agency must develop a diagnostic surveillance program for H5/H7 low pathogenic avian influenza for all poultry in the State. The exact provisions of the...

  16. Beam property studies in the PLS diagnostic beamline

    CERN Document Server

    Ko, I S; Seon, D K; Kim, C B; Lee, T Y

    1999-01-01

    A diagnostic beamline has been operated in the Pohang Light Source (PLS) storage ring for the diagnostics of electron and photon beam properties. It consists of two 1:1 imaging systems: a visible-light imaging system and a soft X-ray imaging system. We have measured the transverse and the longitudinal structures of beams by using a streak camera to obtain a visible image. Accurate transverse beam size have been measured to be 186 mu m horizontally and 43.1 mu m vertically by using soft X-ray images with minimum diffraction errors. The corresponding emittances are 11.7 nm-rad horizontally and 0.59 nm-rad vertically. By comparing the measured data with the design values, we confirmed that the PLS storage ring has reached its designed performance within an error of 3.3 % in the transverse direction.

  17. Study of the performance of diagnostic radiology instruments during calibration

    International Nuclear Information System (INIS)

    Freitas, Rodrigo N. de; Vivolo, Vitor; Potiens, Maria da Penha A.

    2008-01-01

    Full text: The instruments used in diagnostic radiology measurements represent 8 % of the tested instruments by the calibration laboratory of IPEN annually (approximately 1600 in 2007). Considering that the calibration of this kind of instrument is performed biannually it is possible to conclude that almost 300 instruments are being used to measure the air kerma in diagnostic radiology clinics to determine the in beam values (in front of the patient), attenuated measurements (behind the patient) and scattered radiation. This work presents the results of the calibration of the instruments used in mammography, computed tomography, dental and conventional diagnostic radiology dosimetry, performed during the period of 2005 to 2007. Their performances during the calibrations measurements were evaluated. Although at the calibration laboratory there are three available series of radiation quality to this type of calibration (RQR, N and M, according to standards IEC 61267 and ISO 4037-1.), the applications can be assorted (general radiology, computed tomography, mammography, radiation protection and fluoroscopy). Depending on its design and behaviour , one kind of instrument can be used for one or more type of applications. The instruments normally used for diagnostic radiology measurements are ionization chambers with volumes varying from 3 to 1800 cm 3 , and can be cylindrical, spherical or plane parallel plates kind. They usually are sensitive to photon particles, with energies greater than 15 keV and can be used up to 1200 keV. In this work they were tested in X radiation fields from 25 to 150 kV, in specific qualities depending on the utilization of the instrument. The calibration results of 390 instruments received from 2005 to 2007 were analyzed. About 20 instruments were not able to be calibrated due to bad functioning. The calibration coefficients obtained were between 0.88 and 1.24. The uncertainties were always less than ± 3.6% to instruments used in scattered

  18. Studies on ethno medicinal plant diversity in an urban area – a case study

    Directory of Open Access Journals (Sweden)

    Sudipta Biswas

    2016-08-01

    Full Text Available The present study deals with the Ethno-medicinal plants used by the local communities in Santragachhi area, under Howrah Municipal Corporation, ward no. 38, District Howrah, West Bengal, India. An ethno medicinal survey was carried out the use of medicinal plants in Santragachi region. The information was gathered from the local community people using an integrated approach botanical collections, group discussion and interview with questionnaire during 2012-2013. Among 50 informants interviewed, 10 were tribal practitioners. A total of 53 genera and 33 families are documented. In most of case, fresh parts of the plants were used for the preparation of medicine. The results further revealed that the natives of this area are not very much practiced in using the medicinal plants in the treatment of human illness. The study area is delimited by number of wetlands and the people collect the aquatic plants by their habitual knowledge as food resources. But due to expansion of city area, road construction causes loss of plant diversity and random exploitation of natural resources many valuable medicinal plants are at the stage of extinction. The present study documented ethno medicinal plants were mostly used for treatment of various diseases.

  19. Applications of a surveillance and diagnostics methodology using neutron noise from a pressurized-water reactor

    International Nuclear Information System (INIS)

    Wood, R.T.; Miller, L.F.; Perez, R.B.

    1992-01-01

    Two applications of a noise diagnostic methodology were performed with ex-core neutron detector data from a pressurized-water reactor (PWR). A feedback dynamics model of the neutron power spectral denisty was derived from a low-order whole-plant physical model made stochastic with the Langevin technique. From a functional fit to plant data, the response of the dynamic system to changes in important physical parameters was evaluated by a direct sensitivity analysis. In addition, changes in monitored spectra were related to changes in physical parameters, and detection thresholds using common surveillance discriminants were determined. A resonance model was developed from perturbation theory to give the ex-core neutron detector response for small in-core mechanical motions in terms of a pole-strength factor, a resonance asymmetry (or skewness) factor, a vibration damping factor, and a frequency of vibration. The mechanical motion paramters for several resonances were determined by a functional fit of the model to plant data taken at various times during a fuel cycle and were tracked to determined trends that indicated vibrational changes of reactor internals. In addition, the resonance model gave the ability to separate the resonant components of the power spectral density after the parameters had been identified. As a result, the behavior of several vibration peaks was monitored over a fuel cycle. The noise diagnostic methodology illustrated by these applications can be used in monitoring the condition of the reactor system. Early detection of degraded mechanical components or undesirable operating conditions by using such surveillance and diagnostic techniques would enhance plant safety. 15 refs., 6 figs., 1 tab

  20. Preferred Reporting Items for a Systematic Review and Meta-analysis of Diagnostic Test Accuracy Studies: The PRISMA-DTA Statement.

    Science.gov (United States)

    McInnes, Matthew D F; Moher, David; Thombs, Brett D; McGrath, Trevor A; Bossuyt, Patrick M; Clifford, Tammy; Cohen, Jérémie F; Deeks, Jonathan J; Gatsonis, Constantine; Hooft, Lotty; Hunt, Harriet A; Hyde, Christopher J; Korevaar, Daniël A; Leeflang, Mariska M G; Macaskill, Petra; Reitsma, Johannes B; Rodin, Rachel; Rutjes, Anne W S; Salameh, Jean-Paul; Stevens, Adrienne; Takwoingi, Yemisi; Tonelli, Marcello; Weeks, Laura; Whiting, Penny; Willis, Brian H

    2018-01-23

    Systematic reviews of diagnostic test accuracy synthesize data from primary diagnostic studies that have evaluated the accuracy of 1 or more index tests against a reference standard, provide estimates of test performance, allow comparisons of the accuracy of different tests, and facilitate the identification of sources of variability in test accuracy. To develop the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) diagnostic test accuracy guideline as a stand-alone extension of the PRISMA statement. Modifications to the PRISMA statement reflect the specific requirements for reporting of systematic reviews and meta-analyses of diagnostic test accuracy studies and the abstracts for these reviews. Established standards from the Enhancing the Quality and Transparency of Health Research (EQUATOR) Network were followed for the development of the guideline. The original PRISMA statement was used as a framework on which to modify and add items. A group of 24 multidisciplinary experts used a systematic review of articles on existing reporting guidelines and methods, a 3-round Delphi process, a consensus meeting, pilot testing, and iterative refinement to develop the PRISMA diagnostic test accuracy guideline. The final version of the PRISMA diagnostic test accuracy guideline checklist was approved by the group. The systematic review (produced 64 items) and the Delphi process (provided feedback on 7 proposed items; 1 item was later split into 2 items) identified 71 potentially relevant items for consideration. The Delphi process reduced these to 60 items that were discussed at the consensus meeting. Following the meeting, pilot testing and iterative feedback were used to generate the 27-item PRISMA diagnostic test accuracy checklist. To reflect specific or optimal contemporary systematic review methods for diagnostic test accuracy, 8 of the 27 original PRISMA items were left unchanged, 17 were modified, 2 were added, and 2 were omitted. The 27-item

  1. The value of diagnostic information to patients with suspected multiple sclerosis. Rochester-Toronto MRI Study Group.

    Science.gov (United States)

    Mushlin, A I; Mooney, C; Grow, V; Phelps, C E

    1994-01-01

    To determine the value of diagnostic information to patients with suspected multiple sclerosis (MS). Because treatment choices would be only minimally affected by earlier diagnosis for most patients with this clinical problem, this study assessed the "nondecisional" value of diagnosis. Prospective survey of patients before and after diagnostic workup, including imaging with magnetic resonance scanning. We assessed the effect of diagnostic information on patients' sense of well-being, as well as direct measures of the utility of information (using time trade-off and willingness-to-pay techniques). Patients referred from primary care practices for diagnostic workup for suspected MS to neurology clinics and practices. Sixty-eight individuals, mean age 37.5 years, 53 female and 15 male. Thirty-one patients were classified as having "probable MS," and 37 were classified as having "possible MS" by the examining neurologist before workup. Present and future health perception, uncertainty about diagnosis-prognosis, and level of anxiety. Willingness to pay for diagnostic information, quality of life as measured by the time trade-off technique, and psychological state of the patient before and after diagnosis. Diagnostic uncertainty fell significantly as a result of the diagnostic workup. Most patients (59/62) said that they were better off having received diagnostic information. Although anxiety seemed to be reduced by testing, overall anxiety levels did not decrease as much as anticipated. Patients also became less optimistic about their future health after testing. On average, patients were willing to forgo 4.5 quality-adjusted life days to receive an earlier diagnosis and their quality of life after diagnosis improved slightly. Subgroups of patients differed in their response to diagnostic information. Those in whom no definitive diagnosis emerged tend to be more anxious rather than being reassured by the "negative" workup. Individuals with "positive" workups became less

  2. Effect of patient age awareness on diagnostic agreement of chronic or aggressive periodontitis between clinicians; a pilot study

    OpenAIRE

    Oshman, Sarah; El Chaar, Edgard; Lee, Yoonjung Nicole; Engebretson, Steven

    2016-01-01

    Background The aim of this pilot study was to test whether diagnostic agreement of aggressive and chronic periodontitis amongst Board Certified Periodontists, is influenced by knowledge of a patient?s age. In 1999 at the International World Workshop age was removed as a diagnostic criteria for aggressive periodontitis. The impact of this change on the diagnostic reliability amongst clinicians has not yet been assessed. Methods Nine periodontal case reports were twice presented to sixteen boar...

  3. Plant exposure chambers for study of toxic chemical-plant interactions (journal version)

    International Nuclear Information System (INIS)

    McFarlane, J.C.; Pfleeger, T.

    1987-01-01

    Chambers for the study of plant uptake and phytotoxicity of toxic, radio-labeled chemicals are described. The chambers are designed to meet the criteria of continuously stirred tank reactors while providing containment for toxic chemicals. They are computer managed and operated within a controlled-environment room. Besides providing controlled conditions within the contained spaces, continuous measurements are made of various environmental parameters and plant transpiration, net photosynthesis, and dark respiration in up to 18 separate chambers

  4. High-throughput volumetric reconstruction for 3D wheat plant architecture studies

    Directory of Open Access Journals (Sweden)

    Wei Fang

    2016-09-01

    Full Text Available For many tiller crops, the plant architecture (PA, including the plant fresh weight, plant height, number of tillers, tiller angle and stem diameter, significantly affects the grain yield. In this study, we propose a method based on volumetric reconstruction for high-throughput three-dimensional (3D wheat PA studies. The proposed methodology involves plant volumetric reconstruction from multiple images, plant model processing and phenotypic parameter estimation and analysis. This study was performed on 80 Triticum aestivum plants, and the results were analyzed. Comparing the automated measurements with manual measurements, the mean absolute percentage error (MAPE in the plant height and the plant fresh weight was 2.71% (1.08cm with an average plant height of 40.07cm and 10.06% (1.41g with an average plant fresh weight of 14.06g, respectively. The root mean square error (RMSE was 1.37cm and 1.79g for the plant height and plant fresh weight, respectively. The correlation coefficients were 0.95 and 0.96 for the plant height and plant fresh weight, respectively. Additionally, the proposed methodology, including plant reconstruction, model processing and trait extraction, required only approximately 20s on average per plant using parallel computing on a graphics processing unit (GPU, demonstrating that the methodology would be valuable for a high-throughput phenotyping platform.

  5. Diagnostics upgrade and capability available for physics study on EAST tokamak

    International Nuclear Information System (INIS)

    Hu Liqun

    2013-01-01

    As a consequence of employment of many new techniques and upgrade of EAST superconducting tokamak to enhance divertor plasma performance, significant achievement has been realized in 2012, including 400s long pulse plasma, stationary 35s H-mode and 3.45s H-mode with only ion cyclotron resonant heating (ICRH) etc. To approach steady-state (SS) operation of high-performance plasmas and address key physics on fusion reactor-relevent subjects, recently, capability of the plasma heating and current drive of EAST machine are doubled with total auxiliary injection power over 20 MW, including new methodology of neutral beam injection (NBI) and electron cyclotron resonant heating (ECRH). Most diagnostics have been upgraded to be more compact and integrated due to limited port window and space available, and new advanced neutral-beam related diagnostics have been developed as well, to provide profile of all key parameters for study and understanding critical issues specific to SS high performance plasma. (author)

  6. Substantia nigra fractional anisotropy is not a diagnostic biomarker of Parkinson's disease: A diagnostic performance study and meta-analysis

    Energy Technology Data Exchange (ETDEWEB)

    Hirata, Fabiana C.C.; Vieira, Gilson; Lucato, Leandro T.; Leite, Claudia C.; Pastorello, Bruno F.; Otaduy, Maria C.G.; Chaim, Khallil T.; Campanholo, Kenia R. [University of Sao Paulo, LIM-44, Department of Radiology, Sao Paulo, SP (Brazil); Sato, Joao R. [University of Sao Paulo, LIM-44, Department of Radiology, Sao Paulo, SP (Brazil); Universidade Federal do ABC, Center of Mathematics, Computation and Cognition, Santo Andre (Brazil); Bor-Seng-Shu, Edson; Novaes, Natalia P. [Hospital Israelita Albert Einstein, Sao Paulo (Brazil); University of Sao Paulo, Department of Neurology, Sao Paulo (Brazil); Magalhaes Melo, Luciano; Goncalves, Marcia R.; Reis Barbosa, Egberto [University of Sao Paulo, Department of Neurology, Sao Paulo (Brazil); Pereira do Nascimento, Felipe Barjud; Amaro, Edson [University of Sao Paulo, LIM-44, Department of Radiology, Sao Paulo, SP (Brazil); Hospital Israelita Albert Einstein, Sao Paulo (Brazil); Jacobsen Teixeira, Manoel [University of Sao Paulo, Department of Neurosurgery, Sao Paulo (Brazil); Cardoso, Ellison Fernando [University of Sao Paulo, LIM-44, Department of Radiology, Sao Paulo, SP (Brazil); Hospital Israelita Albert Einstein, Sao Paulo (Brazil); Institute of Mathematics and Statistics University of Sao Paulo (IME-USP), Sao Paulo (Brazil)

    2017-06-15

    Our goal was to estimate the diagnostic accuracy of substantia nigra fractional anisotropy (SN-FA) for Parkinson's disease (PD) diagnosis in a sample similar to the clinical setting, including patients with essential tremor (ET) and healthy controls (HC). We also performed a systematic review and meta-analysis to estimate mean change in SN-FA induced by PD and its diagnostic accuracy. Our sample consisted of 135 subjects: 72 PD, 21 ET and 42 HC. To address inter-scanner variability, two 3.0-T MRI scans were performed. MRI results of this sample were pooled into a meta-analysis that included 1,432 subjects (806 PD and 626 HC). A bivariate model was used to evaluate diagnostic accuracy measures. In our sample, we did not observe a significant effect of disease on SN-FA and it was uninformative for diagnosis. The results of the meta-analysis estimated a 0.03 decrease in mean SN-FA in PD relative to HC (CI: 0.01-0.05). However, the discriminatory capability of SN-FA to diagnose PD was low: pooled sensitivity and specificity were 72 % (CI: 68-75) and 63 % (CI: 58-70), respectively. There was high heterogeneity between studies (I{sup 2} = 91.9 %). SN-FA cannot be used as an isolated measure to diagnose PD. (orig.)

  7. Development of a real time chemistry monitoring and diagnostic system

    International Nuclear Information System (INIS)

    Gaudreau, T.M.; Millett, P.J.; Bates, J.; Burns, G.

    1998-01-01

    EPRI has developed SMART chem WORKS, which is capable of operating as a real time chemistry diagnostic and monitoring system. A high degree of plant-specific customization is possible which allows discrimination between normal chemistry and off-normal conditions. The initial implementation of the system has been very successful. State of the art technology has been employed which allows remote administration of the system, a flexible, web page display of the output from the system and instant notification of excursions using email and pagers. The second installation of SMART chem WORKS is currently underway at a BWR plant, Grand Gulf. The SMART chem WORKS techniques can be applied to monitor PWR Primary Chemistry, PWR Secondary Chemistry and BWR steam cycle chemistry. A fossil steam cycle simulator will also be developed for application to fossil plants. (J.P.N.)

  8. NSTX Diagnostics for Fusion Plasma Science Studies

    International Nuclear Information System (INIS)

    Kaita, R.; Johnson, D.; Roquemore, L.; Bitter, M.; Levinton, F.; Paoletti, F.; Stutman, D.

    2001-01-01

    This paper will discuss how plasma science issues are addressed by the diagnostics for the National Spherical Torus Experiment (NSTX), the newest large-scale machine in the magnetic confinement fusion (MCF) program. The development of new schemes for plasma confinement involves the interplay of experimental results and theoretical interpretations. A fundamental requirement, for example, is a determination of the equilibria for these configurations. For MCF, this is well established in the solutions of the Grad-Shafranov equation. While it is simple to state its basis in the balance between the kinetic and magnetic pressures, what they are as functions of space and time are often not easy to obtain. Quantities like the plasma pressure and current density are not directly measurable. They are derived from data that are themselves complex products of more basic parameters. The same difficulties apply to the understanding of plasma instabilities. Not only are the needs for spatial and temporal resolution more stringent, but the wave parameters which characterize the instabilities are difficult to resolve. We will show how solutions to the problems of diagnostic design on NSTX, and the physics insight the data analysis provides, benefits both NSTX and the broader scientific community

  9. Plant systems/components modularization study. Final report

    International Nuclear Information System (INIS)

    1977-07-01

    The final results are summarized of a Plant Systems/Components Modularization Study based on Stone and Webster's Pressurized Water Reactor Reference Design. The program has been modified to include evaluation of the most promising areas for modular consideration based on the level of the Sundesert Project engineering design completion and the feasibility of their incorporation into the plant construction effort

  10. A computerized diagnostic system for nuclear plant control rooms based on statistical quality control

    International Nuclear Information System (INIS)

    Heising, C.D.; Grenzebach, W.S.

    1990-01-01

    In engineering science, statistical quality control techniques have traditionally been applied to control manufacturing processes. An application to commercial nuclear power plant maintenance and control is presented that can greatly improve safety. As a demonstration of such an approach to plant maintenance and control, a specific system is analyzed: the reactor coolant pumps of the St. Lucie Unit 2 nuclear power plant located in Florida. A 30-day history of the four pumps prior to a plant shutdown caused by pump failure and a related fire within the containment was analyzed. Statistical quality control charts of recorded variables were constructed for each pump, which were shown to go out of statistical control many days before the plant trip. The analysis shows that statistical process control methods can be applied as an early warning system capable of identifying significant equipment problems well in advance of traditional control room alarm indicators

  11. Development of plant condition measurement - The Jimah Model

    Science.gov (United States)

    Evans, Roy F.; Syuhaimi, Mohd; Mazli, Mohammad; Kamarudin, Nurliyana; Maniza Othman, Faiz

    2012-05-01

    The Jimah Model is an information management model. The model has been designed to facilitate analysis of machine condition by integrating diagnostic data with quantitative and qualitative information. The model treats data as a single strand of information - metaphorically a 'genome' of data. The 'Genome' is structured to be representative of plant function and identifies the condition of selected components (or genes) in each machine. To date in industry, computer aided work processes used with traditional industrial practices, have been unable to consistently deliver a standard of information suitable for holistic evaluation of machine condition and change. Significantly the reengineered site strategies necessary for implementation of this "data genome concept" have resulted in enhanced knowledge and management of plant condition. In large plant with high initial equipment cost and subsequent high maintenance costs, accurate measurement of major component condition becomes central to whole of life management and replacement decisions. A case study following implementation of the model at a major power station site in Malaysia (Jimah) shows that modeling of plant condition and wear (in real time) can be made a practical reality.

  12. Development of plant condition measurement - The Jimah Model

    International Nuclear Information System (INIS)

    Evans, Roy F; Syuhaimi, Mohd; Mazli, Mohammad; Kamarudin, Nurliyana; Othman, Faiz Maniza

    2012-01-01

    The Jimah Model is an information management model. The model has been designed to facilitate analysis of machine condition by integrating diagnostic data with quantitative and qualitative information. The model treats data as a single strand of information - metaphorically a 'genome' of data. The 'Genome' is structured to be representative of plant function and identifies the condition of selected components (or genes) in each machine. To date in industry, computer aided work processes used with traditional industrial practices, have been unable to consistently deliver a standard of information suitable for holistic evaluation of machine condition and change. Significantly the reengineered site strategies necessary for implementation of this 'data genome concept' have resulted in enhanced knowledge and management of plant condition. In large plant with high initial equipment cost and subsequent high maintenance costs, accurate measurement of major component condition becomes central to whole of life management and replacement decisions. A case study following implementation of the model at a major power station site in Malaysia (Jimah) shows that modeling of plant condition and wear (in real time) can be made a practical reality.

  13. Assessing the utility of diagnostic criteria: a multi-site study on gender identity disorder

    NARCIS (Netherlands)

    Paap, Muirne; Kreukels, Baudewijntje P.C.; Cohen-Kettenis, Peggy; Richter-Appelt, Hertha; De Cuypere, Griet; Haraldsen, Ira R.

    2011-01-01

    Introduction: Studies involving patients with gender identity disorder (GID) are inconsistent with regard to outcomes and often difficult to compare because of the vague descriptions of the diagnostic process. A multisite study is needed to scrutinize the utility and generality of different aspects

  14. Study of nuclear power plant stability. Trip criteria

    International Nuclear Information System (INIS)

    Beato Castro, D.; Iturbe Uriarte, R.; Wilhelmi Ayza, J.R.

    1993-01-01

    The influence that nuclear power plants and high voltage power systems have on each other when confronted by disturbances in the offsite network may lead, due to dynamic effects, to plant trip. It is therefore necessary to study the disturbances in the network and the effects on plant equipment by means of dynamic simulations which evaluate the unit protection system and the auxiliary services so as to obtain maximum unit availability without jeopardizing its safety. These studies can be conducted since there are models and software tools capable of simulating dynamic behaviour of the electric system, including the excitation systems and specific speed governors obtainment of valid. (author)

  15. A study on the Fusion Reactor - Development of charge exchange recombination spectroscopy for tokamak diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Tong Nyong; Kim, Dong Eon; Kim, Dae Sung; Kim, Seong Ho [Pohang University of Science and Technology, Pohang (Korea, Republic of)

    1996-09-01

    This project has been carried to train people and accumulate the knowledge and techniques related to the measurement of the profiles of ion temperature, toroidal rotation velocity, and fully-stripped ion density in a fusion tokamak plasma by the development of plasma diagnostics using charge exchange recombination (CER) spectroscopy. Daring the 1 st year, the basic study and review on the charge exchange process and the conceptual design and review of the diagnostics have been conducted. In addition, the various atomic data centers around the world have been surveyed and atomic data related to CER have been constructed. The results of this project can be used to the construction and tokamak machine installation of a CER plasma diagnostic to a new superconducting supported by National Fusion Program. 42 refs., 3 tabs., 16 figs. (author)

  16. Feasibility study on Ashuganj NGL Fractionation Plant

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    A feasibility study has been performed on Ashuganj NGL Fractionation Plant being planned in the People's Republic of Bangladesh. The present study has discussed a plant to manufacture liquefied oil gas, automotive fuel, and diesel fuel from liquefied natural gas. The plan calls for the plant life of 20 years, liquefied natural gas as the raw material to be supplied continuously and stably from the gas reservoir areas via the existing pipelines, the storage tank to have a size of 10-day production, and the product to be transported by barges on Meghna River. As a result of the discussions, the liquefied oil gas produced annually will correspond to crude oil of 44,690 tons, and to 858,048 tons of crude oil cumulatively for 20 years of the plant life. This is an energy derived from unutilized natural gas, which is creation of a new energy. With regard to the reduction of global warming gas emission, it was revealed that a reduction effect of 16,540,000 t-CO2 can be obtained in twenty years, if comparison is made based on combustion of firewood. (NEDO)

  17. Feasibility study on Ashuganj NGL Fractionation Plant

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    A feasibility study has been performed on Ashuganj NGL Fractionation Plant being planned in the People's Republic of Bangladesh. The present study has discussed a plant to manufacture liquefied oil gas, automotive fuel, and diesel fuel from liquefied natural gas. The plan calls for the plant life of 20 years, liquefied natural gas as the raw material to be supplied continuously and stably from the gas reservoir areas via the existing pipelines, the storage tank to have a size of 10-day production, and the product to be transported by barges on Meghna River. As a result of the discussions, the liquefied oil gas produced annually will correspond to crude oil of 44,690 tons, and to 858,048 tons of crude oil cumulatively for 20 years of the plant life. This is an energy derived from unutilized natural gas, which is creation of a new energy. With regard to the reduction of global warming gas emission, it was revealed that a reduction effect of 16,540,000 t-CO2 can be obtained in twenty years, if comparison is made based on combustion of firewood. (NEDO)

  18. Study of plant pigment concentration using synchronous luminescence spectroscopy

    International Nuclear Information System (INIS)

    Pawar, B.H.; Raghuvanshi, F.C.; Mahalle, N.S.; Munde, B.S.; Devhade, S.K.; Arsad, S.S.; Kadam, K.P.; Pachkawade, A.P.; Hiswankar, S.U.

    2006-01-01

    We have recorded the SL (Synchronous Luminescence) spectra emitted by several plant leaves. We investigate in detail SL spectra emitted by the leaf of the plants like Hibiscus Schizopetalus, Ficus Benghalensis, Ficus Religiosa and Ficus Glomerata and study the concentration of the pigments in the plant leaves and the mechanism of photosynthesis process taking place in the leaves. The SL spectra have several features which may help in revealing the density and structure of the molecules present in the samples. The SL spectra exhibit two, three, four and five peaked structure. The peak appear at different wavelengths and their spectral widths are also different. The chlorophyll, xanthophyll and carotene concentration may be obtained from the study of the spectra. The plant species may be identified from the study of SL spectroscopy. (author)

  19. Use of artificial intelligence in nuclear power plants

    International Nuclear Information System (INIS)

    Uhrig, R.E.

    1990-01-01

    The application of artificial intelligence, in the form of expert systems and neural networks, to the control room activities in a nuclear power plant has the potential to reduce operator error and increase plant safety, reliability, and efficiency. Furthermore, there are a large number of non-operating activities (testing, routine maintenance, outage planning, equipment diagnostics, and fuel management) in which artificial intelligence can increase the efficiency and effectiveness of overall plant and corporate operations. This paper reviews the state-of-the-art of artificial intelligence techniques, specifically, expert systems and neural networks, to nuclear power plants. This paper has reviewed the state-of-the-art of artificial intelligence, specifically expert systems and neural networks that are applied to problems in nuclear power plants

  20. The effect of information types on diagnostic strategies in the information aid

    International Nuclear Information System (INIS)

    Kim, Jong Hyun; Seong, Poong Hyun

    2007-01-01

    Through experiments, this paper investigates the compatibility of information types with the diagnostic strategy in information aid. Compatibility with operator strategies is an important requirement for information aiding systems in nuclear power plants (NPPs). This paper used three typical types of information aids for MCR operators to investigate the effect of the aids on diagnostic strategies: 'alarm (A),' 'hypothesis on faults (H),' and 'hypothesis on faults and expected symptoms (HS).' The experimental results indicate that the effectiveness of information aid types can vary, dependent on the strategies subjects employ. The results also show that the HS aid improved the diagnosis performance in the hypothesis-and-test strategy

  1. Molecular diagnostic development for begomovirus-betasatellite complexes undergoing diversification: A case study.

    Science.gov (United States)

    Brown, Judith K; Ur-Rehman, Muhammad Zia; Avelar, Sofia; Chingandu, N; Hameed, Usman; Haider, Saleem; Ilyas, Muhammad

    2017-09-15

    At least five begomoviral species that cause leaf curl disease of cotton have emerged recently in Asia and Africa, reducing fiber quality and yield. The potential for the spread of these viruses to other cotton-vegetable growing regions throughout the world is extensive, owing to routine, global transport of alternative hosts of the leaf curl viruses, especially ornamentals. The research reported here describes the design and validation of polymerase chain reaction (PCR) primers undertaken to facilitate molecular detection of the two most-prevalent leaf curl-associated begomovirus-betasatellite complexes in the Indian Subcontinent and Africa, the Cotton leaf curl Kokhran virus-Burewala strain and Cotton leaf curl Gezira virus, endemic to Asia and Africa, respectively. Ongoing genomic diversification of these begomoviral-satellite complexes was evident based on nucleotide sequence alignments, and analysis of single nucleotide polymorphisms, both factors that created new challenges for primer design. The additional requirement for species and strain-specific, and betasatellite-specific primer design, imposes further constraints on primer design and validation due to the large number of related species and strains extant in 'core leaf curl virus complex', now with expanded distribution in south Asia, the Pacific region, and Africa-Arabian Peninsula that have relatively highly conserved coding and non-coding regions, which precludes much of the genome-betasatellite sequence when selecting primer 'targets'. Here, PCR primers were successfully designed and validated for detection of cloned viral genomes and betasatellites for representative 'core leaf curl' strains and species, distant relatives, and total DNA isolated from selected plant species. The application of molecular diagnostics to screen plant imports prior to export or release from ports of entry is expected to greatly reduce the likelihood of exotic leaf curl virus introductions that could dramatically affect

  2. Phytotoxic studies of medicinal plant species of Pakistan

    International Nuclear Information System (INIS)

    Gilani, S.A.; Adnan, M.; Kikuchi, A.; Fujii, Y.; Shinwari, Z.K.; Kazuo, N.; Watanabe, K.N.

    2010-01-01

    Allelopathic screening of 81 medicinal plant species, collected from North West Frontier Province (NWFP) Pakistan, was carried out to identify significantly higher allelopathic species for future phyto chemical analyses. For this purpose, sandwich method was used to test allelopathic potentials of leaf leachates of these plant species against lettuce seeds (Lactuca sativa L.). Two different concentrations of 10 mg and 50 mg of leaf leachates were used in the study. The radicle and hypocotyl growths were measured and compared with control treatments. It was observed that an endemic species Seriphidium kurramense, Andrachne cordifolia and Rhazya stricta were the stronger phyto toxic plants as compared to the other test species. Based on the current screening, three potential medicinal plants are recommended for future bioassay guided isolation of allelochemicals and for genetic diversity studies. It would also be interesting to see correlation between genetic markers and isolated allelochemicals. (author)

  3. Australian diagnostic radiographers' attitudes and perceptions of imaging obese patients: A study of self, peers and students

    International Nuclear Information System (INIS)

    Aweidah, L.; Robinson, J.; Cumming, S.; Lewis, S.

    2016-01-01

    Introduction and Objective: Imaging obese patients poses a number of challenges for diagnostic radiographers through positioning, radiation exposure, communication and care. Furthermore, the increasing prevalence of obesity in Australian society ensures these imaging challenges are more frequent however little is known about this area. This study aims to explore the attitudes and perceptions of diagnostic radiographers toward imaging obese patients through a mixed methods study. Methods: Ethics approval was granted to interview and survey diagnostic radiographers about their attitudes and perceptions of imaging obese patients. Twelve diagnostic radiographers who are designated clinical educators (DR CEs) took part in a 30–45 min semi-structured interview as well as a 20 min computer-based Weight Implicit Association Test (Weight-IAT) and self-report questionnaire of explicit attitudes. An additional 25 experienced Diagnostic Radiographers who were associate supervisors completed the Weight-IAT/explicit questionnaire only. Results: Thematic analysis of the interviews revealed that DR CEs adopted an image-focussed or patient-focussed approach to obese patients. Key themes with a negative bias included blame, tolerance and insecurity of skill. Positively associated key themes were empathy and experience in radiography. The sample overall showed a significant negative implicit weight bias (P = 0.016) as measured by the Weight-IAT and there was no evidence of negative explicit attitudes. Conclusion: Australian diagnostic radiographers in this study exhibited significant negative implicit weight bias, with interview results highlighting attitudes of blame and frustration towards obese patients. DR CEs were more likely to be focussed on image acquisition rather than patient considerations, with fewer responses related to empathy and equity. - Highlights: • Mixed-methods study combining qualitative interviews and implicit–explicit bias towards imaging obese

  4. Development of an experimental approach to study coupled soil-plant-atmosphere processes using plant analogs

    Science.gov (United States)

    Trautz, Andrew C.; Illangasekare, Tissa H.; Rodriguez-Iturbe, Ignacio; Heck, Katharina; Helmig, Rainer

    2017-04-01

    The atmosphere, soils, and vegetation near the land-atmosphere interface are in a state of continuous dynamic interaction via a myriad of complex interrelated feedback processes which collectively, remain poorly understood. Studying the fundamental nature and dynamics of such processes in atmospheric, ecological, and/or hydrological contexts in the field setting presents many challenges; current experimental approaches are an important factor given a general lack of control and high measurement uncertainty. In an effort to address these issues and reduce overall complexity, new experimental design considerations (two-dimensional intermediate-scale coupled wind tunnel-synthetic aquifer testing using synthetic plants) for studying soil-plant-atmosphere continuum soil moisture dynamics are introduced and tested in this study. Validation of these experimental considerations, particularly the adoption of synthetic plants, is required prior to their application in future research. A comparison of three experiments with bare soil surfaces or transplanted with a Stargazer lily/limestone block was used to evaluate the feasibility of the proposed approaches. Results demonstrate that coupled wind tunnel-porous media experimentation, used to simulate field conditions, reduces complexity, and enhances control while allowing fine spatial-temporal resolution measurements to be made using state-of-the-art technologies. Synthetic plants further help reduce system complexity (e.g., airflow) while preserving the basic hydrodynamic functions of plants (e.g., water uptake and transpiration). The trends and distributions of key measured atmospheric and subsurface spatial and temporal variables (e.g., soil moisture, relative humidity, temperature, air velocity) were comparable, showing that synthetic plants can be used as simple, idealized, nonbiological analogs for living vegetation in fundamental hydrodynamic studies.

  5. An exploratory study demonstrating the diagnostic ability of healthcare professionals in primary care using online case studies for common skin conditions.

    Science.gov (United States)

    Tucker, Rod; Patel, Mahendra; Layton, Alison L; Walton, Shernaz

    2014-04-01

    To compare the diagnostic ability of pharmacists, nurses and general practitioners (GPs) for a range of skin conditions. An online study comprising 10 specifically developed dermatological case studies containing a digital image of the skin condition and a short case history. A total of 60 participants (20 representing each of pharmacists, GPs and primary care nurses) were required to identify the skin condition as well as the features in the case history that supported the diagnosis and the recommended first-line management approach for the condition. The mean diagnostic scores for each group were GPs = 8.8 (95% confidence interval, CI, 7.9-9.6), pharmacists = 6.2 (95% CI, 5.4-6.9) and nurses = 7.0 (95% CI, 6.1-7.9). Post hoc analysis revealed that the difference in mean diagnostic scores was significant (P skin conditions such as tinea corporis, scabies and plantar warts and overall at least 40% of pharmacists correctly identified all conditions. This small study has demonstrated that for all of the skin conditions considered, pharmacists' overall diagnostic scores were significantly different from those of GPs but similar to those of nurses for the conditions assessed. However, further work with a larger sample is required to determine the accuracy of these preliminary findings and to establish whether advice given by pharmacists in practice results in the appropriate course of action being taken. © 2013 Royal Pharmaceutical Society.

  6. Plant monitoring and signal validation at HFIR

    International Nuclear Information System (INIS)

    Mullens, J.A.

    1991-01-01

    This paper describes a monitoring system for the Oak Ridge National Laboratory's (ORNL'S) High Flux Isotope Reactor (HFIR). HFIR is an 85 MW pressurized water reactor designed to produce isotopes and intense neutron beams. The monitoring system is described with respect to plant signals and computer system; monitoring overview; data acquisition, logging and network distribution; signal validation; status displays; reactor condition monitoring; reactor operator aids. Future work will include the addition of more plant signals, more signal validation and diagnostic capabilities, improved status display, integration of the system with the RELAP plant simulation and graphical interface, improved operator aids, and an alarm filtering system. 8 refs., 7 figs. (MB)

  7. Recent diagnostic developments on LHD

    International Nuclear Information System (INIS)

    Sudo, S.; Nagayama, Y.; Peterson, B.J.

    2003-01-01

    Standard diagnostics for fundamental plasma parameters and for plasma physics are routinely utilized for daily operation and physics study in the large helical device (LHD) with high reliability. Diagnostics for steady state plasma are intensively developed, especially for T e , n e (YAG laser Thomson, CO 2 laser polarimeter), data acquisition in steady state, heat resistant probes. To clarify the plasma property of the helical structure, 2-D or 3-D diagnostics are intensively developed: Tangential cameras (Fast SX TV, Photon counting CCD, H α TV); Tomography (Tangential SX CCD, Bolometer); Imaging (Bolometer, ECE, Reflectometer). Divertor and edge physics are one of important key issues for steady state operation. Diagnostics for neutral flux (H α array, Zeeman spectroscopy) and n e (Fast scanning probe, Li beam probe, Pulsed radar reflectometer). In addition to these, advanced diagnostics are being intensively developed with national and international collaborations in LHD. (author)

  8. Recent advances in control and diagnostics development and application

    International Nuclear Information System (INIS)

    Monson, L.R.; King, R.W.; Lindsay, R.W.; Staffon, J.D.

    1989-01-01

    The power industry is undergoing rapid technological advances and cultural changes. Technologies are advancing and evolving so rapidly that the industry is hard pressed to keep up and take full advantage of the many developments now in progress. Recent advantages in state-of-the-art computer technology are making in-roads in the form of advanced computer control, expert systems, on-line performance monitoring and diagnostics. Validation and verification schemes are being developed which provide increased confidence in the correctness and reliability of both computer hardware and software. Our challenge in the nuclear community is to effectively apply these new technologies to improve the operation, safety, and reliability of our plants. This presentation discusses two areas of development that are essential to advanced control strategies: application of diagnostic systems to improve fault-tolerance, and model-based graphic displays. 4 refs., 4 figs

  9. Personalized estimates of radiation dose from dedicated breast CT in a diagnostic population and comparison with diagnostic mammography

    International Nuclear Information System (INIS)

    Vedantham, Srinivasan; Shi, Linxi; Karellas, Andrew; O'Connell, Avice M; Conover, David L

    2013-01-01

    This study retrospectively analyzed the mean glandular dose (MGD) to 133 breasts from 132 subjects, all women, who participated in a clinical trial evaluating dedicated breast CT in a diagnostic population. The clinical trial was conducted in adherence to a protocol approved by institutional review boards and the study participants provided written informed consent. Individual estimates of MGD to each breast from dedicated breast CT was obtained by combining x-ray beam characteristics with estimates of breast dimensions and fibroglandular fraction from volumetric breast CT images, and using normalized glandular dose coefficients. For each study participant and for the breast corresponding to that imaged with breast CT, an estimate of the MGD from diagnostic mammography (including supplemental views) was obtained from the DICOM image headers for comparison. This estimate uses normalized glandular dose coefficients corresponding to a breast with 50% fibroglandular weight fraction. The median fibroglandular weight fraction for the study cohort determined from volumetric breast CT images was 15%. Hence, the MGD from diagnostic mammography was corrected to be representative of the study cohort. Individualized estimates of MGD from breast CT ranged from 5.7 to 27.8 mGy. Corresponding to the breasts imaged with breast CT, the MGD from diagnostic mammography ranged from 2.6 to 31.6 mGy. The mean (± inter-breast SD) and the median MGD (mGy) from dedicated breast CT exam were 13.9 ± 4.6 and 12.6, respectively. For the corresponding breasts, the mean (± inter-breast SD) and the median MGD (mGy) from diagnostic mammography were 12.4 ± 6.3 and 11.1, respectively. Statistical analysis indicated that at the 0.05 level, the distributions of MGD from dedicated breast CT and diagnostic mammography were significantly different (Wilcoxon signed ranks test, p = 0.007). While the interquartile range and the range (maximum–minimum) of MGD from dedicated breast CT was lower than

  10. Diagnostic accuracy in virtual dermatopathology

    DEFF Research Database (Denmark)

    Mooney, E.; Kempf, W.; Jemec, G.B.E.

    2012-01-01

    Background Virtual microscopy is used for teaching medical students and residents and for in-training and certification examinations in the United States. However, no existing studies compare diagnostic accuracy using virtual slides and photomicrographs. The objective of this study was to compare...... diagnostic accuracy of dermatopathologists and pathologists using photomicrographs vs. digitized images, through a self-assessment examination, and to elucidate assessment of virtual dermatopathology. Methods Forty-five dermatopathologists and pathologists received a randomized combination of 15 virtual...... slides and photomicrographs with corresponding clinical photographs and information in a self-assessment examination format. Descriptive data analysis and comparison of groups were performed using a chi-square test. Results Diagnostic accuracy in dermatopathology using virtual dermatopathology...

  11. On-Line Monitoring and Diagnostics of the Integrity of Nuclear Plant Steam Generators and Heat Exchangers

    International Nuclear Information System (INIS)

    Upadhyaya, Belle R.; Wesley Hines, J.

    2004-01-01

    The overall purpose of this Nuclear Engineering Education Research (NEER) project was to integrate new, innovative, and existing technologies to develop a fault diagnostics and characterization system for nuclear plant steam generators (SG) and heat exchangers (HX). Issues related to system level degradation of SG and HX tubing, including tube fouling, performance under reduced heat transfer area, and the damage caused by stress corrosion cracking, are the important factors that influence overall plant operation, maintenance, and economic viability of nuclear power systems. The research at The University of Tennessee focused on the development of techniques for monitoring process and structural integrity of steam generators and heat exchangers. The objectives of the project were accomplished by the completion of the following tasks. All the objectives were accomplished during the project period. This report summarizes the research and development activities, results, and accomplishments during June 2001-September 2004. (1) Development and testing of a high-fidelity nodal model of a U-tube steam generator (UTSG) to simulate the effects of fouling and to generate a database representing normal and degraded process conditions. Application of the group method of data handling (GMDH) method for process variable prediction. (2) Development of a laboratory test module to simulate particulate fouling of HX tubes and its effect on overall thermal resistance. Application of the GMDH technique to predict HX fluid temperatures, and to compare with the calculated thermal resistance. (3) Development of a hybrid modeling technique for process diagnosis and its evaluation using laboratory heat exchanger test data. (4) Development and testing of a sensor suite using piezo-electric devices for monitoring structural integrity of both flat plates (beams) and tubing. Experiments were performed in air, and in water with and without bubbly flow. (5) Development of advanced signal

  12. On-Line Monitoring and Diagnostics of the Integrity of Nuclear Plant Steam Generators and Heat Exchangers.

    Energy Technology Data Exchange (ETDEWEB)

    Belle R. Upadhyaya; J. Wesley Hines

    2004-09-27

    The overall purpose of this Nuclear Engineering Education Research (NEER) project was to integrate new, innovative, and existing technologies to develop a fault diagnostics and characterization system for nuclear plant steam generators (SG) and heat exchangers (HX). Issues related to system level degradation of SG and HX tubing, including tube fouling, performance under reduced heat transfer area, and the damage caused by stress corrosion cracking, are the important factors that influence overall plant operation, maintenance, and economic viability of nuclear power systems. The research at The University of Tennessee focused on the development of techniques for monitoring process and structural integrity of steam generators and heat exchangers. The objectives of the project were accomplished by the completion of the following tasks. All the objectives were accomplished during the project period. This report summarizes the research and development activities, results, and accomplishments during June 2001-September 2004. (1) Development and testing of a high-fidelity nodal model of a U-tube steam generator (UTSG) to simulate the effects of fouling and to generate a database representing normal and degraded process conditions. Application of the group method of data handling (GMDH) method for process variable prediction. (2) Development of a laboratory test module to simulate particulate fouling of HX tubes and its effect on overall thermal resistance. Application of the GMDH technique to predict HX fluid temperatures, and to compare with the calculated thermal resistance. (3) Development of a hybrid modeling technique for process diagnosis and its evaluation using laboratory heat exchanger test data. (4) Development and testing of a sensor suite using piezo-electric devices for monitoring structural integrity of both flat plates (beams) and tubing. Experiments were performed in air, and in water with and without bubbly flow. (5) Development of advanced signal

  13. Tele-maintenance 'intelligent' system for technical plants result management

    International Nuclear Information System (INIS)

    Concetti, Massimo; Cuccioletta, Roberto; Fedele, Lorenzo; Mercuri, Giampiero

    2009-01-01

    The management of technical plant for productivity and safety is generally a complex activity, particularly when many plants distributed in the territory are considered (i.e. the more and more frequent case of outsourced plants maintenance by specialized companies), granted quality and cost results are required (i.e. the case of some rather innovative contract solutions) and the technology involved is heterogeneous and innovative (i.e. electro-mechanical plants). In order to efficiently achieve the above aims an 'intelligent' maintenance-management system for the distant monitoring and controlling by a remote control center has been developed. The so-called GrAMS (granted availability management system) system is conceived to give to organizations involved in technical-industrial plants management the possibility to tend to a 'well-known availability' and 'zero-failures' management. In particular, this study deals with the diagnostic aspects and safety level of technical plants (such as elevators, thermo-technical plants, etc.), and with the involvement of ad hoc designed software analysis tools based on neural networks and reliability indicators. Part of the research dealing with the tele-maintenance intelligent system has been financed by the Italian High Institute for Safety (ISPESL) and led to the development of a pre-industrial prototype whose realization and testing is here described

  14. Student Interpretations of Diagnostic Feedback

    Science.gov (United States)

    Doe, Christine

    2015-01-01

    Diagnostic assessment is increasingly being recognized as a potentially beneficial tool for teaching and learning (Jang, 2012). There have been calls in the research literature for students to receive diagnostic feedback and for researchers to investigate how such feedback is used by students. Therefore, this study examined how students…

  15. The Oncogenic Risks of Diagnostic CT Scam Studies in Children

    International Nuclear Information System (INIS)

    Brent, R.

    2004-01-01

    Brenner et al (2001) reported that estimates of the exposure to children from CT scans indicates that the exposures are both higher than from conventional radiographic studies and higher than is necessary to obtain quality examinations. utilizing the oncogenic risk data from the RERF study in Japan, Brenner et al estimated that the oncogenic risk in this population of CT exposed children exposed each year would result in an additional 500 cases of cancer. This risk estimate is supported by the RERF epidemiological data obtained from the populations exposed in Hiroshima and Nagasaki. the increased risks associated with the increased exposure from CT scans have raised concern and stimulated discussion. Although there is little doubt about the benefits of CT scans in improving the health care of children, there is concern about the estimated oncogenic risk, especially since the frequency of CT studies has been increasing. Applying the oncogenic risks of ionizing radiation from the RERF data may not be appropriate for all types of radiation exposure for accurately predicting the incidence of cancer in exposed children because of the impact of 1) partial versus whole-body irradiation, and 2) the protraction of the exposure. Other population of children who have been exposed to radiation and whose incidence of cancer has been studied will be presented and those studies indicate that the risk of cancer is much lower or not increased at all with exposures in the diagnostic range. finally, the dramatic impact of the use of CT scans in clinical pediatric practice saves lives and improves diagnostic accuracy. Therefore, it is crucial that a scholarly evaluation of the risks and benefits should be initiated. The radiology community and the manufacturers have already initiated programs to decrease the exposure significantly. But it is essential that well-planned, retrospective and prospective epidemiology studies should be initiated to study the oncogenic risks. If you want to

  16. Second generation plant health clinics in Uganda

    DEFF Research Database (Denmark)

    Danielsen, Solveig; Matsiko, Frank; Mutebi, Emmanuel

    coverage, Regularity/timeliness and Quality of plant healthcare. Field work was carried out over 15 months between July 2010 and September 2011 in 13 districts in the eastern, central and western parts of Uganda. A total of 205 plant clinic sessions were held in the period. The plant clinics received 2...... from the clinics to diagnostic laboratories. Although the plant clinics have become part of Ministry policy and districts showed increasing interest and commitment, there are some structural barriers that made it difficult for the districts to institutionalise the clinics and for the Ministry to play...... their leading role. A mismatch between institutional mandates/authority and allocated resources limited the scope of the actions both at district and national level. The plant clinics risk ‘falling between the two chairs’ of extension and pest and disease control. Finding a solid institutional base...

  17. AECL's plant Information Technologies

    International Nuclear Information System (INIS)

    DeVerno, M.; Lupton, L.; Didsbury, R.; Judd, R.

    1998-01-01

    The competitiveness of the world-wide energy market is a continual driving force for improvements to CANDU performance and lower operating, maintenance, and administration costs. As in other industries, advanced Information Technologies (IT) are changing the way we work and conduct business. The nuclear industry is no different and there exists strong incentives to improve work processes and provide faster and more flexible access to the information needed to effectively manage and maintain nuclear plant assets. AECL has responded to these forces through the development of a vision of integrated IT systems addressing all phases of nuclear plant development and operations. This includes the initial engineering, design, and construction processes as well as support to the long-term operations and maintenance. Integral to the AECL vision is the need for cost-effective engineering and operational configuration management systems, proactive maintenance processes and systems, and advanced plant surveillance and diagnostics. This paper presents the vision and describes the integrated information systems needed to manage both the design basis and operating plant data systems to ensure the cost-effective, long-term viability of CANDU plants. (author)

  18. Potential Study of Water Extraction from Selected Plants

    Directory of Open Access Journals (Sweden)

    Musa S.

    2017-01-01

    Full Text Available Water is absorbed by the roots of a plant and transported subsequently as a liquid to all parts of the plant before being released into the atmosphere as transpiration. In this study, seven(7selected plant species collected from urban, rural and forested areas were studied and characterized. The water was collected using transparent plastic bag that being tied to the tree branches. Then, the vapouris water trapped inside the plastic bag and through the condensation process, it become water droplets. Water quality parameters such as temperature, pH value, DO, turbidity, colour, magnesium, calcium, nitrate and chloride were analyzed. The analysis was compared to drinking water quality standard set by the Ministry of Health Malaysia. Based on the results, it shows that banana leaf has a higher rate of water extraction compared to others. Thus, the plant can be categorised as a helpful guide for emergency use of water or as an alternative source to survival.

  19. Diagnostics vehicle’s condition using obd-ii and raspberry pi technology: study literature

    Science.gov (United States)

    Moniaga, J. V.; Manalu, S. R.; Hadipurnawan, D. A.; Sahidi, F.

    2018-03-01

    Transportation accident rate are still being a major challenge in many countries. There are many factors that could be cause transportation accident, especially in vehicle’s internal system problem. To overcome this problem, OBD-II technology has been created to diagnostics vehicle’s condition. OBD-II scanner plugged to OBD-II port or usually called Data Link Connector (DLC), and after that it sends the diagnostics to Raspberry Pi. Compared from another microcontrollers, Arduino, Raspberry Pi are chosen because it sustains the application to receive real-time diagnostics, process the diagnostics and send command to automobiles at the same time, rather than Arduino that must wait for another process finished to run another process. Outcome from this application is to enable automobile’s user to diagnostics their own vehicles. If there is found something unusual or a problem, the application can told the problem to user, so they could know what to fix before they use their vehicle safely.

  20. Diagnostic labelling influences self-rated health. A prospective cohort study: the HUNT Study, Norway.

    Science.gov (United States)

    Jørgensen, Pål; Langhammer, Arnulf; Krokstad, Steinar; Forsmo, Siri

    2015-10-01

    Studies have shown an independent association between poor self-rated health (SRH) and increased mortality. Few studies, however, have investigated any possible impact on SRH of diagnostic labelling. To test whether SRH differed in persons with known and unknown hypothyroidism, diabetes mellitus (DM) or hypertension, opposed to persons without these conditions, after 11-year follow-up. Prospective population-based cohort study in North-Trøndelag County, Norway, HUNT2 (1995-97) to HUNT3 (2006-08). All inhabitants aged 20 years and older were invited. The response rate was 69.5% in HUNT2 and 54.1% in HUNT3. In total, 34144 persons aged 20-70 years were included in the study population. The outcome was poor SRH. Persons with known disease had an increased odds ratio (OR) to report poor SRH at follow-up; figures ranging from 1.11 (0.68-1.79) to 2.52 (1.46-4.34) (men with hypothyroidism kept out owing to too few numbers). However, in persons not reporting, but having laboratory results indicating these diseases (unknown disease), no corresponding associations with SRH were found. Contrary, the OR for poor SRH in women with unknown hypothyroidism and unknown hypertension was 0.64 (0.38-1.06) and 0.89 (0.79-1.01), respectively. Awareness opposed to ignorance of hypothyroidism, DM and hypertension seemed to be associated with poor perceived health, suggesting that diagnostic labelling could have a negative effect on SRH. This relationship needs to be tested more thoroughly in future research but should be kept in mind regarding the benefits of early diagnosing of diseases. © The Author 2015. Published by Oxford University Press.

  1. Clinical Factors and Disease Course Related to Diagnostic Delay in Korean Crohn's Disease Patients: Results from the CONNECT Study.

    Directory of Open Access Journals (Sweden)

    Chang Mo Moon

    Full Text Available Diagnostic delay frequently occurs in Crohn's disease (CD patients because of diagnostic limitations. However, diagnostic delay and its related factors remain poorly defined. Therefore, we aimed to identify the predictors associated with diagnostic delay and to evaluate the impact of diagnostic delay on clinical course in a Korean CD patient cohort. We performed a multicenter retrospective analysis of 1,047 CD patients registered in the Crohn's Disease Clinical Network and Cohort study in Korea. The mean interval of diagnostic delay was 16.0 ± 33.1 months. Multivariate analysis showed that older age at diagnosis (≥40 years (p = 0.014, concomitant upper gastrointestinal (UGI disease (p = 0.012 and penetrating disease behavior at diagnosis (p = 0.001 were positively associated with long diagnostic delay (≥18 months. During the longitudinal follow-up, long diagnostic delay was independently predictive of further development of intestinal stenosis (hazard ratio [HR], 1.43; 95% confidence interval [CI], 1.07-1.93; p = 0.017, internal fistulas (HR, 1.62; 95% CI, 1.12-2.33; p = 0.011, and perianal fistulas (HR, 1.38; 95% CI, 1.06-1.80; p = 0.016. However, as for the risk of abscess formation, bowel perforation, and CD-related abdominal surgery, no significant association with diagnostic delay was observed. Older age at diagnosis, UGI involvement, and penetrating behavior are associated with long diagnostic delay in Korean CD patients. Moreover, diagnostic delay is associated with an increased risk of CD-related complications such as intestinal stenosis, internal fistulas, and perianal fistulas.

  2. Diagnostic reliability of MMPI-2 computer-based test interpretations.

    Science.gov (United States)

    Pant, Hina; McCabe, Brian J; Deskovitz, Mark A; Weed, Nathan C; Williams, John E

    2014-09-01

    Reflecting the common use of the MMPI-2 to provide diagnostic considerations, computer-based test interpretations (CBTIs) also typically offer diagnostic suggestions. However, these diagnostic suggestions can sometimes be shown to vary widely across different CBTI programs even for identical MMPI-2 profiles. The present study evaluated the diagnostic reliability of 6 commercially available CBTIs using a 20-item Q-sort task developed for this study. Four raters each sorted diagnostic classifications based on these 6 CBTI reports for 20 MMPI-2 profiles. Two questions were addressed. First, do users of CBTIs understand the diagnostic information contained within the reports similarly? Overall, diagnostic sorts of the CBTIs showed moderate inter-interpreter diagnostic reliability (mean r = .56), with sorts for the 1/2/3 profile showing the highest inter-interpreter diagnostic reliability (mean r = .67). Second, do different CBTIs programs vary with respect to diagnostic suggestions? It was found that diagnostic sorts of the CBTIs had a mean inter-CBTI diagnostic reliability of r = .56, indicating moderate but not strong agreement across CBTIs in terms of diagnostic suggestions. The strongest inter-CBTI diagnostic agreement was found for sorts of the 1/2/3 profile CBTIs (mean r = .71). Limitations and future directions are discussed. PsycINFO Database Record (c) 2014 APA, all rights reserved.

  3. Silicon drift detector based X-ray spectroscopy diagnostic system for the study of non-thermal electrons at Aditya tokamak.

    Science.gov (United States)

    Purohit, S; Joisa, Y S; Raval, J V; Ghosh, J; Tanna, R; Shukla, B K; Bhatt, S B

    2014-11-01

    Silicon drift detector based X-ray spectrometer diagnostic was developed to study the non-thermal electron for Aditya tokamak plasma. The diagnostic was mounted on a radial mid plane port at the Aditya. The objective of diagnostic includes the estimation of the non-thermal electron temperature for the ohmically heated plasma. Bi-Maxwellian plasma model was adopted for the temperature estimation. Along with that the study of high Z impurity line radiation from the ECR pre-ionization experiments was also aimed. The performance and first experimental results from the new X-ray spectrometer system are presented.

  4. Patterns of anaphylaxis after diagnostic workup

    DEFF Research Database (Denmark)

    Oropeza, Athamaica Ruiz; Bindslev-Jensen, Carsten; Broesby-Olsen, Sigurd

    2017-01-01

    BACKGROUND: Most published studies on anaphylaxis are retrospective or register based. Data on subsequent diagnostic work-up are sparse. We aimed to characterize patients seen with suspected anaphylaxis at the emergency care setting (ECS), after subsequent diagnostic work-up at our Allergy Center...... (AC). METHODS: Prospective study including patients from the ECS, Odense University Hospital, during May 2013-April 2014. Possible anaphylaxis cases were daily identified based on a broad search profile including history and symptoms in patient records, diagnostic codes and pharmacological treatments....... At the AC, all patients were evaluated according to international guidelines. RESULTS: Among 226 patients with suspected anaphylaxis, the diagnosis was confirmed in 124 (54.9%) after diagnostic work-up; 118 of the 124 fulfilled WAO/EAACI criteria of anaphylaxis at the ECS, while 6 were found among 46...

  5. Polychromatic holographic plasma diagnostics

    International Nuclear Information System (INIS)

    Zhiglinskij, A.G.; Morozov, A.O.

    1992-01-01

    Review of holographic interferometry properties is performed and advantages of this method by plasma diagnostics are indicated. Main results obtained by the method of holographic interferometry in studies of various-type plasmas are considered. Special attention is paid to multiwave plasma diagnostics, the necessity of which is related as a rule to multicomponent composition of plasma. The eight laser and gas-discharge sources and holographic schemes, which make it possible to realize plasma polychromatic and holographic interferometry, are considered. The advantages of the method are demonstrated by examples of polychromatic holographic diagnostics of arc discharge and discharge in a hollow cathode. Review of theoretical works determining the applicability area of resonance polychromatic interferometry is carried out

  6. Skeletal diseases. Diagnostic clinical radiology and differential diagnostics. 2. rev. and enl. ed.

    International Nuclear Information System (INIS)

    Freyschmidt, J.

    1997-01-01

    The book focuses on the diagnostic evaluation of idiopathic diseases of the skeleton and bone joints, also including the fundamental healing processes of bone fractures, particularly of stress-induced and pathologic fractures. Ample space has been given to the description and imaging of the course of diseases under treatment by up-to-date therapies, as e.g. for ostitis deformans Paget's disease, or skeletal metastases. This second edition of the book incorporates the progress achieved over the last five years in skeletal diagnostics. The advances in this field have been resulting from basic research work, for instance in molecular biology, or from a variety of completed studies relating to clinical medicine, laboratory chemistry, histopathology and radiology of skeletal diseases, and from experience obtained with the diagnostic radiology methods and techniques, with the potentials and constraints of magnetic resonance imaging (MRI) today being more critically assessed than five years ago. MRI is a modality currently meeting with interest in the context of search for additional diagnostic information, new definition of complete pictures of diseases, or false or overinterpretation of diagnostic findings. (orig./MG). 431 figs [de

  7. Simulation study on unfolding methods for diagnostic X-rays and mixed gamma rays

    International Nuclear Information System (INIS)

    Hashimoto, Makoto; Ohtaka, Masahiko; Ara, Kuniaki; Kanno, Ikuo; Imamura, Ryo; Mikami, Kenta; Nomiya, Seiichiro; Onabe, Hideaki

    2009-01-01

    A photon detector operating in current mode that can sense X-ray energy distribution has been reported. This detector consists of a row of several segment detectors. The energy distribution is derived using an unfolding technique. In this paper, comparisons of the unfolding techniques among error reduction, spectrum surveillance, and neural network methods are discussed through simulation studies on the detection of diagnostic X-rays and gamma rays emitted by a mixture of 137 Cs and 60 Co. For diagnostic X-ray measurement, the spectrum surveillance and neural network methods appeared promising, while the error reduction method yielded poor results. However, in the case of measuring mixtures of gamma rays, the error reduction method was both sufficient and effective. (author)

  8. Diagnostic radiography exposure increases the risk for thyroid microcarcinoma: a population-based case-control study.

    Science.gov (United States)

    Zhang, Yawei; Chen, Yingtai; Huang, Huang; Sandler, Jason; Dai, Min; Ma, Shuangge; Udelsman, Robert

    2015-09-01

    Thyroid cancer incidence and diagnostic radiography exposures, particularly computed tomography (CT) scanning and nuclear medicine examinations, have increased substantially in the USA. However, very few epidemiologic studies have directly investigated their associations. A population-based case-control study was conducted in Connecticut in 2010-2011, including 462 histologically confirmed incident thyroid cancer cases and 498 population-based controls. Multivariate unconditional logistic regression models were used to estimate the associations between diagnostic radiography and the risk of thyroid cancer, controlling for potential confounding factors. Exposure to any form of diagnostic radiography was associated with an increased risk of well-differentiated thyroid microcarcinoma [tumor size≤10 mm, odds ratio (OR)=2.76, 95% confidence interval (CI): 1.31-5.81]. The highest risk increase occurred with nuclear medicine examinations (excluding cardiology tests and thyroid uptake studies; OR=5.47, 95% CI: 2.10-14.23), followed by chest CT scanning (OR=4.30, 95% CI: 1.66-11.14), head and neck CT scanning (OR=3.88, 95% CI: 1.75-8.63), upper gastrointestinal series (OR=3.56, 95% CI: 1.54-8.21), lower gastrointestinal series (OR=3.29, 95% CI: 1.41-7.66), kidney radiography involving dye injection into a vein or artery (OR=3.21, 95% CI: 1.20-8.54), mammography (OR=2.95, 95% CI: 1.14-7.61), chest radiography (OR=2.93, 95% CI: 1.37-6.29), and abdomen CT scanning (OR=2.54, 95% CI: 1.02-6.30). No significant associations were found between these imaging modalities and thyroid tumors larger than 10 mm. This study provides the first direct evidence that CT scanning and nuclear medicine examinations are associated with an increased risk of thyroid cancer. The novel finding that an array of diagnostic radiography procedures are associated with thyroid microcarcinomas warrants further investigation.

  9. Diagnostic criteria for CRPS I: differences between patient profiles using three different diagnostic sets.

    Science.gov (United States)

    Perez, Roberto S G M; Collins, Susan; Marinus, Johan; Zuurmond, Wouter W A; de Lange, Jaap J

    2007-11-01

    Complex Regional Pain Syndrome type I (CRPS I) is an illness which usually occurs due to major or minor tissue injury to the extremities. Because a unique pathophysiological mechanism for CRPS I has not yet been established, the diagnosis is based on observation and measurement of clinical symptoms and signs. In this study, a comparison was made between three sets of diagnostic criteria (the IASP, Bruehl et al. and Veldman et al.) based on patient reports and physicians' assessments of signs and symptoms associated with CRPS I, in 372 outpatients suspected of having CRPS I. Agreement between CRPS I diagnosis among the three sets was poor (kappa-range: 0.29-0.42), leading to positive CRPS I diagnoses according to Veldman et al.'s criteria in 218 cases (59%), according to the IASP in 268 cases (72%), and according to Bruehl et al. in 129 cases (35%). Significant differences in patient profiles were found between the diagnostic sets for the number of patients reporting continuing disproportionate pain, larger area affected than the initial trauma (both pCRPS I were found for reported hyperesthesia (SE+SP:165%), allodynia (160%), observed color asymmetry (162%), hyperesthesia (157%), temperature asymmetry (154%) and edema (152%). The lack of agreement between the different diagnostic sets for CRPS I and the different clinical profiles that result from it may lead to different therapeutic and study populations, hampering adequate treatment and scientific development for this illness. We propose explicit reference to diagnostic criteria used in studies, and registration in trials of a broad variety of CRPS I features, as used in this study, to make subgroup phenotyping and post hoc analyses based on different diagnostic criteria possible.

  10. Development of electromagnetic induction diagnostics technology for condition based maintenance

    International Nuclear Information System (INIS)

    Mawatari, Shingo; Oeda, Kaoru; Yatogi, Hideo; Fukuchi, Taira; Ueno, Tadashi

    2008-01-01

    In ROKKASHO Reprocessing Plant (below, called 'RRP'), we have applied Condition Based Maintenance to rotating equipment with vibration diagnostics technology. However, a few rotating equipment are difficult to diagnose definitely, because have structural problems which exercise vibrational noise to peripheral and be impossible to install vibratory sensor. Electromagnetic induction diagnostics technology which measure magnetic fields to eddy current which is induced to rotary through static magnetic field, diagnose deterioration behavior such as abrasion and crack. As a result, it has possibilities to clear above problems. Therefore, we started our basic researches with this technology for Condition Based Maintenance. In this paper, it introduces basic data about 'Non-seal pump' that have installed in RRP. As a result, this technology is a possibility that be able to detect Condition Based Maintenance. (author)

  11. Vibration monitoring/diagnostic techniques, as applied to reactor coolant pumps

    International Nuclear Information System (INIS)

    Sculthorpe, B.R.; Johnson, K.M.

    1986-01-01

    With the increased awareness of reactor coolant pump (RCP) cracked shafts, brought about by the catastrophic shaft failure at Crystal River number3, Florida Power and Light Company, in conjunction with Bently Nevada Corporation, undertook a test program at St. Lucie Nuclear Unit number2, to confirm the integrity of all four RCP pump shafts. Reactor coolant pumps play a major roll in the operation of nuclear-powered generation facilities. The time required to disassemble and physically inspect a single RCP shaft would be lengthy, monetarily costly to the utility and its customers, and cause possible unnecessary man-rem exposure to plant personnel. When properly applied, vibration instrumentation can increase unit availability/reliability, as well as provide enhanced diagnostic capability. This paper reviews monitoring benefits and diagnostic techniques applicable to RCPs/motor drives

  12. Nuclear power plant monitoring and fault diagnosis methods based on the artificial intelligence technique

    International Nuclear Information System (INIS)

    Yoshikawa, S.; Saiki, A.; Ugolini, D.; Ozawa, K.

    1996-01-01

    The main objective of this paper is to develop an advanced diagnosis system based on the artificial intelligence technique to monitor the operation and to improve the operational safety of nuclear power plants. Three different methods have been elaborated in this study: an artificial neural network local diagnosis (NN ds ) scheme that acting at the component level discriminates between normal and abnormal transients, a model-based diagnostic reasoning mechanism that combines a physical causal network model-based knowledge compiler (KC) that generates applicable diagnostic rules from widely accepted physical knowledge compiler (KC) that generates applicable diagnostic rules from widely accepted physical knowledge. Although the three methods have been developed and verified independently, they are highly correlated and, when connected together, form a effective and robust diagnosis and monitoring tool. (authors)

  13. Studying the Impact of Spaceflight Environment on Immune Functions Using New Molecular Diagnostics System

    Science.gov (United States)

    Cohen, Luchino

    Immune functions are altered during space flights. Latent virus reactivation, reduction in the number of immune cells, decreased cell activation and increased sensitivity of astronauts to infections following their return on Earth demonstrate that the immune system is less efficient during space flight. The causes of this immune deficiency are not fully understood and this dysfunction during long-term missions could result in the appearance of opportunistic infections or a decrease in the immuno-surveillance mechanisms that eradicate cancer cells. Therefore, the immune functions of astronauts will have to be monitored continuously during long-term missions in space, using miniature and semi-automated diagnostic systems. The objectives of this project are to study the causes of space-related immunodeficiency, to develop countermeasures to maintain an optimal immune function and to improve our capacity to detect infectious diseases during space missions through the monitoring of astronauts' immune system. In order to achieve these objectives, an Immune Function Diagnostic System (IFDS) will be designed to perform a set of immunological assays on board spacecrafts or on planet-bound bases. Through flow cytometric assays and molecular biology analyses, this diagnostic system could improve medical surveillance of astronauts and could be used to test countermeasures aimed at preventing immune deficiency during space missions. The capacity of the instrument to assess cellular fluorescence and to quantify the presence of soluble molecules in biological samples would support advanced molecular studies in space life sciences. Finally, such diagnostic system could also be used on Earth in remote areas or in mobile hospitals following natural disasters to fight against infectious diseases and other pathologies.

  14. A new adult appendicitis score improves diagnostic accuracy of acute appendicitis - a prospective study

    Science.gov (United States)

    2014-01-01

    Background The aim of the study was to construct a new scoring system for more accurate diagnostics of acute appendicitis. Applying the new score into clinical practice could reduce the need of potentially harmful diagnostic imaging. Methods This prospective study enrolled 829 adults presenting with clinical suspicion of appendicitis, including 392 (47%) patients with appendicitis. The collected data included clinical findings and symptoms together with laboratory tests (white cell count, neutrophil count and C-reactive protein), and the timing of the onset of symptoms. The score was constructed by logistic regression analysis using multiple imputations for missing values. Performance of the constructed score in patients with complete data (n = 725) was compared with Alvarado score and Appendicitis inflammatory response score. Results 343 (47%) of patients with complete data had appendicitis. 199 (58%) patients with appendicitis had score value at least 16 and were classified as high probability group with 93% specificity.Patients with score below 11 were classified as low probability of appendicitis. Only 4% of patients with appendicitis had a score below 11, and none of them had complicated appendicitis. In contrast, 207 (54%) of non-appendicitis patients had score below 11. There were no cases with complicated appendicitis in the low probability group. The area under ROC curve was significantly larger with the new score 0.882 (95% CI 0.858 – 0.906) compared with AUC of Alvarado score 0.790 (0.758 – 0.823) and Appendicitis inflammatory response score 0.810 (0.779 – 0.840). Conclusions The new diagnostic score is fast and accurate in categorizing patients with suspected appendicitis, and roughly halves the need of diagnostic imaging. PMID:24970111

  15. New technology in nuclear power plant instrumentation and control

    International Nuclear Information System (INIS)

    Anon.

    1985-01-01

    The primary topic of this book is what can be done to improve nuclear power plant operation safety and the economic benefits that can be gained with the utilization of advance instrumentation and control technology. Other topics discussed are the industry's reluctance to accept new designs determining cost effective improvements, and difficulties in meeting regulatory standards with new technology control. The subjects will be useful when considering the area of instrumentation and control for enhancing plant operation and safety. Contents: Advanced Instrumention, Plant Control and Monitoring, Plant Diagnostics and Failure Detection, Human Factors Considerations in Instrumentation and Control, NRC and Industry Perspective on Advanced Instrumentation and Control

  16. Study about diagnostic quality in a public-center of mammography of Santa Fe, Argentina

    International Nuclear Information System (INIS)

    Lescano, R.; Kiguen, J.; Gaitan, L.; Caspani, C.

    2001-01-01

    The objective is to apply a method that allows us to evaluate the diagnostic quality of a public-center of mammography and to validate it. The representative centers of a social class were grouped; this one is evaluated measuring the mechanics, electrics, dosimetrics and personal parameters of the process to get the mammography diagnostic. The original study and the respective report was submitted to the valuation of a panel of experts, who evaluated image, techniques and diagnostics. The equipment and techniques used are described in this case. The judgment of the ACR and the Argentine legislation are applied. The dosimetric results of the mammography practice serve to determine the local reference levels. The people who intervened in the diagnosis are evaluated, as well as the services that can influence it. Seeking the parametric sensibility in relationship with the succeeded and precocious diagnosis, the success of it is confirmed by the panel of experts. We conclude by indicating that the success percentage in the diagnosis is about 98,36%, that there is 100% of coincidence among the perception and the value of the study quality. The valuation of the image reaches 69,2% of the maximum score, and the placement technique, 73,9%. The parametric sensibilities of the principal variables are discussed. (author)

  17. Power Plant Replacement Study

    Energy Technology Data Exchange (ETDEWEB)

    Reed, Gary

    2010-09-30

    This report represents the final report for the Eastern Illinois University power plant replacement study. It contains all related documentation from consideration of possible solutions to the final recommended option. Included are the economic justifications associated with the chosen solution along with application for environmental permitting for the selected project for construction. This final report will summarize the results of execution of an EPC (energy performance contract) investment grade audit (IGA) which lead to an energy services agreement (ESA). The project includes scope of work to design and install energy conservation measures which are guaranteed by the contractor to be self-funding over its twenty year contract duration. The cost recovery is derived from systems performance improvements leading to energy savings. The prime focus of this EPC effort is to provide a replacement solution for Eastern Illinois University's aging and failing circa 1925 central steam production plant. Twenty-three ECMs were considered viable whose net impact will provide sufficient savings to successfully support the overall project objectives.

  18. Power Plant Replacement Study

    Energy Technology Data Exchange (ETDEWEB)

    Reed, Gary

    2010-09-30

    This report represents the final report for the Eastern Illinois University power plant replacement study. It contains all related documentation from consideration of possible solutions to the final recommended option. Included are the economic justifications associated with the chosen solution along with application for environmental permitting for the selected project for construction. This final report will summarize the results of execution of an EPC (energy performance contract) investment grade audit (IGA) which lead to an energy services agreement (ESA). The project includes scope of work to design and install energy conservation measures which are guaranteed by the contractor to be self-funding over its twenty year contract duration. The cost recovery is derived from systems performance improvements leading to energy savings. The prime focus of this EPC effort is to provide a replacement solution for Eastern Illinois University’s aging and failing circa 1925 central steam production plant. Twenty-three ECMs were considered viable whose net impact will provide sufficient savings to successfully support the overall project objectives.

  19. Diagnostic grand rounds: A new teaching concept to train diagnostic reasoning

    International Nuclear Information System (INIS)

    Stieger, Stefan; Praschinger, Andrea; Kletter, Kurt; Kainberger, Franz

    2011-01-01

    Introduction: Diagnostic reasoning is a core skill in teaching and learning in undergraduate curricula. Diagnostic grand rounds (DGRs) as a subform of grand rounds are intended to train the students' skills in the selection of appropriate tests and in the interpretation of test results. The aim of this study was to test DGRs for their ability to improve diagnostic reasoning by using a pre-post-test design. Methods: During one winter term, all 398 fifth-year students (36.1% male, 63.9% female) solved 23 clinical cases presented in 8 DGRs. In an online questionnaire, a Diagnostic Thinking Inventory (DTI) with 41 items was evaluated for flexibility in thinking and structure of knowledge in memory. Results were correlated with those from a summative multiple-choice knowledge test and of the learning objectives in a logbook. Results: The students' DTI scores in the post-test were significantly higher than those reported in the pre-test. DTI scores at either testing time did not correlate with medical knowledge as assessed by a multiple-choice knowledge test. Abilities acquired during clinical clerkships as documented in a logbook could only account for a small proportion of the increase in the flexibility subscale score. This effect still remained significant after accounting for potential confounders. Conclusion: Establishing DGRs proofed to be an effective way of successfully improving both students' diagnostic reasoning and the ability to select the appropriate test method in routine clinical practice.

  20. Diagnostic grand rounds: A new teaching concept to train diagnostic reasoning

    Energy Technology Data Exchange (ETDEWEB)

    Stieger, Stefan, E-mail: stefan.stieger@univie.ac.at [Department of Basic Psychological Research, School of Psychology, University of Vienna, Liebiggasse 5, A-1010 Vienna (Austria); Praschinger, Andrea, E-mail: andrea.praschinger@meduniwien.ac.at [Core Unit for Medical Education (BEMAW), Medical University of Vienna, Spitalgasse 23, BT87, P.O. 10, A-1097 Vienna (Austria); Kletter, Kurt, E-mail: kurt.kletter@meduniwien.ac.at [Department of Nuclear Medicine, General Hospital of Vienna, Waehringer Guertel 18-20, A-1090 Vienna (Austria); Kainberger, Franz, E-mail: franz.kainberger@meduniwien.ac.at [Department of Radiology, General Hospital of Vienna, Waehringer Guertel 18-20, A-1090 Vienna (Austria)

    2011-06-15

    Introduction: Diagnostic reasoning is a core skill in teaching and learning in undergraduate curricula. Diagnostic grand rounds (DGRs) as a subform of grand rounds are intended to train the students' skills in the selection of appropriate tests and in the interpretation of test results. The aim of this study was to test DGRs for their ability to improve diagnostic reasoning by using a pre-post-test design. Methods: During one winter term, all 398 fifth-year students (36.1% male, 63.9% female) solved 23 clinical cases presented in 8 DGRs. In an online questionnaire, a Diagnostic Thinking Inventory (DTI) with 41 items was evaluated for flexibility in thinking and structure of knowledge in memory. Results were correlated with those from a summative multiple-choice knowledge test and of the learning objectives in a logbook. Results: The students' DTI scores in the post-test were significantly higher than those reported in the pre-test. DTI scores at either testing time did not correlate with medical knowledge as assessed by a multiple-choice knowledge test. Abilities acquired during clinical clerkships as documented in a logbook could only account for a small proportion of the increase in the flexibility subscale score. This effect still remained significant after accounting for potential confounders. Conclusion: Establishing DGRs proofed to be an effective way of successfully improving both students' diagnostic reasoning and the ability to select the appropriate test method in routine clinical practice.

  1. System diagnostics using qualitative analysis and component functional classification

    International Nuclear Information System (INIS)

    Reifman, J.; Wei, T.Y.C.

    1993-01-01

    A method for detecting and identifying faulty component candidates during off-normal operations of nuclear power plants involves the qualitative analysis of macroscopic imbalances in the conservation equations of mass, energy and momentum in thermal-hydraulic control volumes associated with one or more plant components and the functional classification of components. The qualitative analysis of mass and energy is performed through the associated equations of state, while imbalances in momentum are obtained by tracking mass flow rates which are incorporated into a first knowledge base. The plant components are functionally classified, according to their type, as sources or sinks of mass, energy and momentum, depending upon which of the three balance equations is most strongly affected by a faulty component which is incorporated into a second knowledge base. Information describing the connections among the components of the system forms a third knowledge base. The method is particularly adapted for use in a diagnostic expert system to detect and identify faulty component candidates in the presence of component failures and is not limited to use in a nuclear power plant, but may be used with virtually any type of thermal-hydraulic operating system. 5 figures

  2. Allowable stem nut wear and diagnostic monitoring for MOVs

    International Nuclear Information System (INIS)

    Swinburne, P.

    1994-01-01

    After a motor-operated valve (MOV) stem nut failure in 1991 that contributed to a forced plant shutdown, the FitzPatrick Plant staff developed criteria to check for excessive stem nut wear in MOVs. Allowable stem nut wear monitoring uses both direct dimensional measurement and diagnostic test data interpretation. The wear allowance is based on the recommended permitted backlash discussed in the Electric Power Research Institute/Nuclear Maintenance Assistance Center Technical Repair Guideline for the Limitorque SMB-000 Motor Actuator. The diagnostic analysis technique measures the time at zero load and compares this with a precalculated allowable zero force time. Excessive zero force time may be the result of other MOV problems, such as a loose stem nut lock nut or excessive free play in the drive sleeve bearing. Stress levels for new or nominal stem nuts and stem nuts with the full wear allowance were compared. Bending and shear stresses at the thread root increase for the maximum wear condition when compared with a open-quotes newclose quotes stem nut. These stresses are directly related to the thread root thickness. For typical MOV loading and common stem threading (with two diameters of thread engagement), the thread stresses are well within acceptable limits for ASTM B584-C86300 (formerly B147-863) manganese bronze (typical stem nut material)

  3. Diagnostic approach to urinary tract infections in male general practice patients: a national surveillance study

    Science.gov (United States)

    den Heijer, Casper DJ; van Dongen, Martien CJM; Donker, Gé A; Stobberingh, Ellen E

    2012-01-01

    Background Diagnostic urinary tract infection (UTI) studies have primarily been performed among female patients. Aim To create a diagnostic algorithm for male general practice patients suspected of UTI. Design and setting Surveillance study in the Dutch Sentinel General Practice Network. Method Clinical information and dipstick results were collected from 603 patients. Algorithm-predicted care was compared with care as usual in terms of sensitivity (antibiotic recommended when UTI was confirmed) and specificity (no antibiotic recommended when no UTI was observed). Results Complete information was available from 490/603 (81%) males, of whom 66% (321/490) had a UTI. A diagnostic algorithm recommending antimicrobial prescription in the case of a positive nitrite test or a positive leukocyte esterase test in males aged ≥60 years, had a positive predictive value (PPV) of 83% (95% confidence interval [CI] = 78 to 87) and a negative predictive value (NPV) of 60% (95% CI = 52 to 66), respectively (area under the ROC curve: 0.78, 95% CI = 0.74 to 0.82). When both dipstick results were positive in males aged ≥60 years, PPV increased to 90% (95% CI = 83 to 94), whereas NPV was highest in males Sensitivity and specificity of predicted UTI care and usual care did not differ (75% versus 79%, P = 0.30, and 70% versus 63%, P = 0.17, respectively). Conclusion UTI care provided to Dutch male GP patients is as accurate as predicted care from a diagnostic algorithm. The studied clinical information and dipstick tests are useful for ruling in UTI in males, but have limited value in ruling out this diagnosis. PMID:23211182

  4. Study of ablation and implosion stages in wire arrays using coupled ultraviolet and X-ray probing diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, A. A.; Ivanov, V. V.; Astanovitskiy, A. L.; Wiewior, P. P.; Chalyy, O. [University of Nevada Reno, Reno, Nevada 89557 (United States); Papp, D. [University of Nevada Reno, Reno, Nevada 89557 (United States); ELI-ALPS, ELI-Hu Nkft., H-6720 Szeged (Hungary)

    2015-11-15

    Star and cylindrical wire arrays were studied using laser probing and X-ray radiography at the 1-MA Zebra pulse power generator at the University of Nevada, Reno. The Leopard laser provided backlighting, producing a laser plasma from a Si target which emitted an X-ray probing pulse at the wavelength of 6.65 Å. A spherically bent quartz crystal imaged the backlit wires onto X-ray film. Laser probing diagnostics at the wavelength of 266 nm included a 3-channel polarimeter for Faraday rotation diagnostic and two-frame laser interferometry with two shearing interferometers to study the evolution of the plasma electron density at the ablation and implosion stages. Dynamics of the plasma density profile in Al wire arrays at the ablation stage were directly studied with interferometry, and expansion of wire cores was measured with X-ray radiography. The magnetic field in the imploding plasma was measured with the Faraday rotation diagnostic, and current was reconstructed.

  5. The study of diagnostic accuracy of chest nodules by using different compression methods

    International Nuclear Information System (INIS)

    Liang Zhigang; Kuncheng, L.I.; Zhang Jinghong; Liu Shuliang

    2005-01-01

    Background: The purpose of this study was to compare the diagnostic accuracy of small nodules in the chest by using different compression methods. Method: Two radiologists with 5 years experience twice interpreted 39 chest images by using lossless and lossy compression methods. The time interval was 3 weeks. Each time the radiologists interpreted one kind of compressed images. The image browser used the Unisight software provided by Atlastiger Company in Shanghai. The interpreting results were analyzed by the ROCKIT software and the ROC curves were painted by Excel 2002. Results: In studies of receiver operating characteristics for scoring the presence or absence of nodules, the images with lossy compression method showed no statistical difference as compared with the images with lossless compression method. Conclusion: The diagnostic accuracy of chest nodules by using the lossless and lossy compression methods had no significant difference, we could use the lossy compression method to transmit and archive the chest images with nodules

  6. Advancing the research agenda for diagnostic error reduction.

    Science.gov (United States)

    Zwaan, Laura; Schiff, Gordon D; Singh, Hardeep

    2013-10-01

    Diagnostic errors remain an underemphasised and understudied area of patient safety research. We briefly summarise the methods that have been used to conduct research on epidemiology, contributing factors and interventions related to diagnostic error and outline directions for future research. Research methods that have studied epidemiology of diagnostic error provide some estimate on diagnostic error rates. However, there appears to be a large variability in the reported rates due to the heterogeneity of definitions and study methods used. Thus, future methods should focus on obtaining more precise estimates in different settings of care. This would lay the foundation for measuring error rates over time to evaluate improvements. Research methods have studied contributing factors for diagnostic error in both naturalistic and experimental settings. Both approaches have revealed important and complementary information. Newer conceptual models from outside healthcare are needed to advance the depth and rigour of analysis of systems and cognitive insights of causes of error. While the literature has suggested many potentially fruitful interventions for reducing diagnostic errors, most have not been systematically evaluated and/or widely implemented in practice. Research is needed to study promising intervention areas such as enhanced patient involvement in diagnosis, improving diagnosis through the use of electronic tools and identification and reduction of specific diagnostic process 'pitfalls' (eg, failure to conduct appropriate diagnostic evaluation of a breast lump after a 'normal' mammogram). The last decade of research on diagnostic error has made promising steps and laid a foundation for more rigorous methods to advance the field.

  7. Corporal diagnostic work and diagnostic spaces: clinicians' use of space and bodies during diagnosis.

    Science.gov (United States)

    Gardner, John; Williams, Clare

    2015-06-01

    An emerging body of literature in sociology has demonstrated that diagnosis is a useful focal point for understanding the social dimensions of health and illness. This article contributes to this work by drawing attention to the relationship between diagnostic spaces and the way in which clinicians use their own bodies during the diagnostic process. As a case study, we draw upon fieldwork conducted with a multidisciplinary clinical team providing deep brain stimulation (DBS) to treat children with a movement disorder called dystonia. Interviews were conducted with team members and diagnostic examinations were observed. We illustrate that clinicians use communicative body work and verbal communication to transform a material terrain into diagnostic space, and we illustrate how this diagnostic space configures forms of embodied 'sensing-and-acting' within. We argue that a 'diagnosis' can be conceptualised as emerging from an interaction in which space, the clinician-body, and the patient-body (or body-part) mutually configure one another. By conceptualising diagnosis in this way, this article draws attention to the corporal bases of diagnostic power and counters Cartesian-like accounts of clinical work in which the patient-body is objectified by a disembodied medical discourse. © 2015 The Authors. Sociology of Health & Illness © 2015 Foundation for the Sociology of Health & Illness.

  8. Systematic review and meta-analysis of studies evaluating diagnostic test accuracy: A practical review for clinical researchers-Part II. general guidance and tips

    International Nuclear Information System (INIS)

    Kim, Kyung Won; Choi, Sang Hyun; Huh, Jimi; Park, Seong Ho; Lee, June Young

    2015-01-01

    Meta-analysis of diagnostic test accuracy studies differs from the usual meta-analysis of therapeutic/interventional studies in that, it is required to simultaneously analyze a pair of two outcome measures such as sensitivity and specificity, instead of a single outcome. Since sensitivity and specificity are generally inversely correlated and could be affected by a threshold effect, more sophisticated statistical methods are required for the meta-analysis of diagnostic test accuracy. Hierarchical models including the bivariate model and the hierarchical summary receiver operating characteristic model are increasingly being accepted as standard methods for meta-analysis of diagnostic test accuracy studies. We provide a conceptual review of statistical methods currently used and recommended for meta-analysis of diagnostic test accuracy studies. This article could serve as a methodological reference for those who perform systematic review and meta-analysis of diagnostic test accuracy studies

  9. Effect of patient age awareness on diagnostic agreement of chronic or aggressive periodontitis between clinicians; a pilot study.

    Science.gov (United States)

    Oshman, Sarah; El Chaar, Edgard; Lee, Yoonjung Nicole; Engebretson, Steven

    2016-07-25

    The aim of this pilot study was to test whether diagnostic agreement of aggressive and chronic periodontitis amongst Board Certified Periodontists, is influenced by knowledge of a patient's age. In 1999 at the International World Workshop age was removed as a diagnostic criteria for aggressive periodontitis. The impact of this change on the diagnostic reliability amongst clinicians has not yet been assessed. Nine periodontal case reports were twice presented to sixteen board certified periodontists, once with age withheld and again with patient age provided. Participants were instructed to choose a diagnosis of Chronic Periodontitis or Aggressive Periodontitis. Diagnostic agreement was calculated using the Fleiss Kappa test. Including the patients' age in case report information increased diagnostic agreement (the kappa statistic) from 0.49 (moderate agreement) to 0.61 (substantial agreement). These results suggest that knowledge of a patients' age influenced clinical diagnosis, when distinguishing between aggressive periodontitis and chronic periodontitis, which may in turn impact treatment decision-making.

  10. 'Kazmer' a complex noise diagnostic system for 1000 MWe PWR WWER type nuclear power units

    International Nuclear Information System (INIS)

    Por, G.

    1992-06-01

    Noise diagnostic systems have previously been developed and installed for the WWER-440 type reactors at the Paks Nuclear Power Plant, Hungary. Based on the experiences, the system has been extended and modified for use in 1000 MWe, WWER-1000 type units. KAZMER consists of three subsystem, the KARD reactor noise diagnostic system, ARGUS vibration monitoring system for rotation machinery, and ALMOS acoustic monitoring system. The installation of the KAZMER system at the Kalinin Nuclear Power Station, Russia, and the first operational experiences are outlined. (R.P.) 15 refs.; 9 figs

  11. Most important methods of the diagnostics of air pollution

    Energy Technology Data Exchange (ETDEWEB)

    Latocha, E; Cimander, B

    1976-01-01

    The paper contains a review of literature concerning the more important procedures for diagnosing air pollution. Cited results of studies from several countries indicate a relationship between the intensity of sulfur dioxide air pollution and the extent of vegetation damage. Possibility of the use of aerial photography for diagnosis of damage in forests was mentioned. Possibilities for utilization of certain plant species or plant communities as indicators of air pollution were described. It was stressed that long-lived evergreens are the best bio-indicators. Examples of increases in population density of certain insect pest sand activation of fungal pathogens caused by industrial emissions were given. Techniques used in Poland for the development and introduction of zones of forest threat by industrial air pollution were discussed. These are based on alterations in the length and shape of needles, foliage coloration, numbers of needle generations, and external appearance of tree crowns in the form of height growth inhibition or impairment of tree vigor. It was stressed that not all changes in forest environment under the impact of emissions may be considered appropriate for the diagnosis of air pollution. Diagnostic procedures ought to be relatively simple and easy to apply.

  12. Diagnostic nerve ultrasonography

    International Nuclear Information System (INIS)

    Baeumer, T.; Grimm, A.; Schelle, T.

    2017-01-01

    For the diagnostics of nerve lesions an imaging method is necessary to visualize peripheral nerves and their surrounding structures for an etiological classification. Clinical neurological and electrophysiological investigations provide functional information about nerve lesions. The information provided by a standard magnetic resonance imaging (MRI) examination is inadequate for peripheral nerve diagnostics; however, MRI neurography is suitable but on the other hand a resource and time-consuming method. Using ultrasonography for peripheral nerve diagnostics. With ultrasonography reliable diagnostics of entrapment neuropathies and traumatic nerve lesions are possible. The use of ultrasonography for neuropathies shows that a differentiation between different forms is possible. Nerve ultrasonography is an established diagnostic tool. In addition to the clinical examination and clinical electrophysiology, structural information can be obtained, which results in a clear improvement in the diagnostics. Ultrasonography has become an integral part of the diagnostic work-up of peripheral nerve lesions in neurophysiological departments. Nerve ultrasonography is recommended for the diagnostic work-up of peripheral nerve lesions in addition to clinical and electrophysiological investigations. It should be used in the clinical work-up of entrapment neuropathies, traumatic nerve lesions and spacy-occupying lesions of nerves. (orig.) [de

  13. Multiplex PCR for specific and robust detection of Xanthomonas campestris pv. musacearum in pure culture and infected plant material

    DEFF Research Database (Denmark)

    Adriko, John; Aritua, V.; Mortensen, Carmen Nieves

    2012-01-01

    The present study developed a pathovar-specific PCR for the detection of Xanthomonas campestris pv. musacearum (Xcm), the cause of banana xanthomonas wilt, by amplification of a 265-bp region of the gene encoding the general secretion pathway protein D (GspD). A distinct DNA fragment......-specific PCR was successfully multiplexed with internal control primers targeting 16S rDNA for application on DNA from bacterial cultures and with primers targeting plant mitochondrial 26S rDNA for application on DNA extracted from plant material. Diagnostic discrimination of healthy and infected plants...

  14. A proof-of-concept transient diagnostic expert system for BWRs [Boiling Water Reactors

    International Nuclear Information System (INIS)

    Yoshida, K.; Naser, J.A.

    1988-05-01

    A proof-of-concept transient diagnostic expert system has been developed to identify the cause and the type of an abnormal transient in a boiling water nuclear power plant. For this expert system development, the calculational results of the simulation code RETRAN were used as the knowledge source. The knowledge extracted from the RETRAN analyses was transformed into IF-THEN rules in the knowledge base for the expert system. An important feature of this expert system is the introduction of certainty factors to allow diagnosis even in the cases where data may be either missing or marked as invalid. To increase the capability of this diagnostic system to distinguish between similiar transients, backward chaining reasoning is used to support the forward chaining reasoning with certainty factors. Through this effort, it has been demonstrated that an expert system can be successfully used to create a transient diagnostic system. It has also successfully demonstrated that RETRAN can be used as the knowledge source for developing the knowledge base of the diagnostic system

  15. Tune-Based Halo Diagnostics

    International Nuclear Information System (INIS)

    Cameron, Peter

    2003-01-01

    Tune-based halo diagnostics can be divided into two categories -- diagnostics for halo prevention, and diagnostics for halo measurement. Diagnostics for halo prevention are standard fare in accumulators, synchrotrons, and storage rings, and again can be divided into two categories -- diagnostics to measure the tune distribution (primarily to avoid resonances), and diagnostics to identify instabilities (which will not be discussed here). These diagnostic systems include kicked (coherent) tune measurement, phase-locked loop (PLL) tune measurement, Schottky tune measurement, beam transfer function (BTF) measurements, and measurement of transverse quadrupole mode envelope oscillations. We refer briefly to tune diagnostics used at RHIC and intended for the SNS, and then present experimental results. Tune-based diagnostics for halo measurement (as opposed to prevention) are considerably more difficult. We present one brief example of tune-based halo measurement

  16. Diagnostic usefulness of endorectal magnetic resonance imaging with dynamic contrast-enhancement in patients with localized prostate cancer. Mapping studies with biopsy specimens

    International Nuclear Information System (INIS)

    Tanaka, Nobumichi; Samma, Shoji; Joko, Masanori; Akiyama, Tatsuya; Takewa, Megumi; Kitano, Satoru; Okajima, Eigoro

    1999-01-01

    New diagnostic criteria for dynamic magnetic resonance (MR) imaging in prostate cancer are presented. The diagnostic usefulness of endorectal MR imaging with dynamic contrast-enhancement in localized prostate cancer and the validity of these criteria were evaluated. Eighteen untreated patients who were suspected of localized prostate cancer were included in the study. They received endorectal dynamic MR imaging before systematic sextant needle biopsy. First, a mapping study with the findings of MR images and histopathology of biopsy specimens was performed in eight patients out of 18 to compare the difference in T2-weighted images with the endorectal coil and the body coil in the same individuals. Second, another mapping study was performed in all 18 patients by analyzing the findings of endorectal dynamic MR images. For the diagnosis of prostate cancer in MR imaging, we offered diagnostic criteria from our experience in addition to those in plain T2-weighted images from the literature. The overall diagnostic rates of endorectal dynamic MR imaging were 88.9% in accuracy, 100% in sensitivity, and 81.8% in specificity. In the comparison of the endorectal and body coils in T2-weighted images in eight patients, there was no difference in the diagnostic rates except for one more histopathologic false positive portion in endorectal MR imaging. In the second mapping study in 18 patients, the diagnostic rates were 92.6% in accuracy, 88.9% in sensitivity and 93.3% in specificity. Endorectal dynamic imaging raised the diagnostic sensitivity from 77.8 to 88.9%. The data demonstrated the validity of this diagnostic criteria and the diagnostic usefulness of endorectal dynamic MR imaging in localized prostate cancer. (author)

  17. Phalaris canariensis L. (Poaceae: A new alien plant record for Kashmir Himalaya, India

    Directory of Open Access Journals (Sweden)

    Shugufta Rasheed

    2016-03-01

    Full Text Available The correct taxonomic identification assumes first and foremost priority in the scientific documentation of biodiversity. The Kashmir Himalaya, located in the north-western side of the Himalayan biodiversity hotspot, is well-known for its diverse flora which merits immediate scientific documentation. In this context, the present study reports Phalaris canariensis L. (Poaceae as a new alien plant record to the flora of Kashmir Himalaya, India. In this paper, a detailed description, photographs, and comparison of diagnostic characters with allied species are provided to scientifically validate this alien plant record for this Himalayan region.

  18. Metabolomics for laboratory diagnostics.

    Science.gov (United States)

    Bujak, Renata; Struck-Lewicka, Wiktoria; Markuszewski, Michał J; Kaliszan, Roman

    2015-09-10

    Metabolomics is an emerging approach in a systems biology field. Due to continuous development in advanced analytical techniques and in bioinformatics, metabolomics has been extensively applied as a novel, holistic diagnostic tool in clinical and biomedical studies. Metabolome's measurement, as a chemical reflection of a current phenotype of a particular biological system, is nowadays frequently implemented to understand pathophysiological processes involved in disease progression as well as to search for new diagnostic or prognostic biomarkers of various organism's disorders. In this review, we discussed the research strategies and analytical platforms commonly applied in the metabolomics studies. The applications of the metabolomics in laboratory diagnostics in the last 5 years were also reviewed according to the type of biological sample used in the metabolome's analysis. We also discussed some limitations and further improvements which should be considered taking in mind potential applications of metabolomic research and practice. Copyright © 2014 Elsevier B.V. All rights reserved.

  19. Fuel-motion diagnostics and cineradiography

    International Nuclear Information System (INIS)

    DeVolpi, A.

    1982-09-01

    Nuclear and non-nuclear applications of cineradiography are reviewed, with emphasis on diagnostic instrumentation for in-pile transient-reactor safety testing of nuclear fuel motion. The primary instrument for this purpose has been the fast-neutron hodoscope, which has achieved quantitative monitoring of time, location, mass, and velocity of fuel movement under the difficult conditions associated with transient-reactor experiments. Alternative diagnostic devices that have been developed have not matched the capabilities of the hodoscope. Other applications for the fuel-motion diagnostic apparatus are also evolving, including time-integrated radiography and direct time- and space-resolved fuel-pin power monitoring. Although only two reactors are now actively equipped with high-resolution fuel-motion diagnostic systems, studies and tests have been carried out in and for many other reactors

  20. Molecular Phytopathology: Current Approaches and Main Directions in Diagnostics of Woody Plant Diseases

    Directory of Open Access Journals (Sweden)

    O. Yu. Baranov

    2014-08-01

    Full Text Available In the article the authors describe the prospects for diagnosis of woody plants diseases based on the use of modern methods of molecular plant pathology. The metagenomic approach based on the analysis of complex pathogens, including non-pathogenic microflora is described. The use the multicopy universal loci characterized by a number of advantages in determining taxonomic affiliation of infectious agents during phytopathological molecular analysis is proposed.

  1. Simulation-based biagnostics and control for nuclar power plants

    International Nuclear Information System (INIS)

    Lee, J.C.

    1993-01-01

    Advanced simulation-based diagnostics and control guidance systems for the identification and management of off-normal transient events in nuclear power plants is currently under investigation. To date a great deal of progress has been made in effectively and efficiently combining information obtained through fuzzy pattern recognition and macroscopic mass and energy inventory analysis for use in multiple failure diagnostics. Work has also begun on the unique problem of diagnostics and surveillance methodologies for advanced passively-safe reactors systems utilizing both statistical and fuzzy information. Plans are also being formulated for the development of deterministic optimal control algorithms combined with Monte Carlo incremental learning algorithms to be used for the flexible and efficient control of reactor transients

  2. A national study of breast and colorectal cancer patients' decision-making for novel personalized medicine genomic diagnostics.

    Science.gov (United States)

    Issa, Amalia M; Tufail, Waqas; Atehortua, Nelson; McKeever, John

    2013-05-01

    Molecular diagnostics are increasingly being used to help guide decision-making for personalized medical treatment of breast and colorectal cancer patients. The main aim of this study was to better understand and determine breast and colorectal cancer patients' decision-making strategies and the trade-offs they make in deciding about characteristics of molecular genomic diagnostics for breast and colorectal cancer. We surveyed a nationally representative sample of 300 breast and colorectal cancer patients using a previously developed web-administered instrument. Eligibility criteria included patients aged 18 years and older with either breast or colorectal cancer. We explored several attributes and attribute levels of molecular genomic diagnostics in 20 scenarios. Our analysis revealed that both breast and colorectal cancer patients weighted the capability of molecular genomic diagnostics to determine the probability of treatment efficacy as being of greater importance than information provided to detect adverse events. The probability of either false-positive or -negative results was ranked highly as a potential barrier by both breast and colorectal patients. However, 78.6% of breast cancer patients ranked the possibility of a 'false-negative test result leading to undertreatment' higher than the 'chance of a false positive, which may lead to overtreatment' (68%). This finding contrasted with the views of colorectal cancer patients who ranked the chance of a false positive as being of greater concern than a false negative (72.8 vs 63%). Overall, cancer patients exhibited a high willingness to accept and pay for genomic diagnostic tests, especially among breast cancer patients. Cancer patients seek a test accuracy rate of 90% or higher. Breast and colorectal cancer patients' decisions about genomic diagnostics are influenced more by the probability of being cured than by avoiding potential severe adverse events. This study provides insights into the relative weight

  3. An ethnopharmacological study of aromatic Uyghur medicinal plants in Xinjiang, China.

    Science.gov (United States)

    Zhao, Lu; Tian, Shuge; Wen, E; Upur, Halmuart

    2017-12-01

    An ethnobotanical survey was completed in a remote village and surrounding country of Xinjiang, where most Uyghur medicinal plants could be collected. This work clarifies and increases ethnobotanical data. We surveyed and organized aromatic medicinal plants that are commonly used in clinical settings to provide a significant reference for studying new medical activities. In the survey, informants who have traditional knowledge on aromatic Uyghur medicinal plants were interviewed between March 2014 and September 2014. Aromatic medicinal plant species and pertinent information were collected. Some therapeutic methods and modes of preparation of traditional aromatic medicinal plants were found. A total of 86 aromatic medicinal plant species belonging to 36 families were included in our study. We identified 34 plant species introduced from different regions such as Europe, India and Mediterranean areas. Fruits and whole plants were the most commonly used parts of plant, and most aromatic medicinal plants could be applied as medicine and food. We assigned the medicinal plants a use value (UV). Knowing the UV of species is useful in determining the use reliability and pharmacological features of related plants. Xinjiang is an area in which indigenous aromatic medicinal plants are diversely used and has therefore established a sound dimensional medical healthcare treatment system. Some aromatic Uyghur medicinal plants are on the verge of extinction. Hence, further strategies for the conservation of these aromatic medicinal plants should be prioritized.

  4. Published diagnostic models safely excluded colorectal cancer in an independent primary care validation study

    NARCIS (Netherlands)

    Elias, Sjoerd G; Kok, Liselotte; Witteman, Ben J M; Goedhard, Jelle G; Romberg-Camps, Mariëlle J L; Muris, Jean W M; de Wit, Niek J; Moons, Karel G M

    OBJECTIVE: To validate published diagnostic models for their ability to safely reduce unnecessary endoscopy referrals in primary care patients suspected of significant colorectal disease. STUDY DESIGN AND SETTING: Following a systematic literature search, we independently validated the identified

  5. Comparative diagnostic study of staging in renal cell carcinoma

    Energy Technology Data Exchange (ETDEWEB)

    Ito, Masaharu; Mori, Masaki; Ito, Sachiko and others

    1986-04-01

    A comparative diagnostic study was carried out on 56 patients with pathologically proven renal cell carcinoma which had been staged by CT, US, angiography (AG) and lymphography (LG) between June, 1980, and May, 1985. The confirmation of the tumor extent was established by surgery and microscopic examination in all patients except three, in whom the extent of the tumor was determined at autopsy. CT and AG were performed in all cases. It was also studied how far various factors such as histologic architecture, cell type, grade, growth mode, tumor necrosis and bleeding were related with prognosis, and how to evaluate them in imaging modality. Concerning the T factor, there was no difference in diagnostic ability between images, and since prognosis of T4 was inferior to those of T2 and T3, diagnosis of T4 was seen to require particular attention. Drawing ability of N and V factors was poor in US. In LG, evaluation of regional lymph nodes was difficult, so this seems to be an unnecessary examination because CT can provide sufficient evaluation. By imaging modality, diagnosis of architecture and cell type was difficult. By AG, avascular to hypovascular tumors were of solid type, and there were many spindle or pleomorphic cell types and combination of tubular-granular types, while the papillary type was few. By macroscopic growth mode, the infiltrating type was poor in prognosis, and the presence or absence of halo was evaluated by CT and AG. Prognosis was favorable in cases having no necrosis in the tumor or accompanied by hemorrhage. For the purpose of diagnosis, CT was found to be sufficient, and it was concluded that AG may be used only for the purpose of renal arterial embolization as a preoperative treatment of low-stage cases subjected to nephrectomy. US is sufficient only if satisfying the role of screening. (J.P.N.).

  6. Intellectual property considerations for molecular diagnostic development with emphasis on companion diagnostics.

    Science.gov (United States)

    Glorikian, Harry; Warburg, Richard Jeremy; Moore, Kelly; Malinowski, Jennifer

    2018-02-01

    The development of molecular diagnostics is a complex endeavor, with multiple regulatory pathways to consider and numerous approaches to development and commercialization. Companion diagnostics, devices which are "essential for the safe and effective use of a corresponding drug or diagnostic product" (see U.S. Food & Drug Administration, In Vitro Diagnostics - Companion Diagnostics, U.S. Dept. of Health & Human Services(2016), available at https://www.fda.gov/medicaldevices/productsandmedicalprocedures/invitrodiagnostics/ucm407297.htm ) and complementary diagnostics, which are more broadly associated with a class of drug, are becoming increasingly important as integral components of the implementation of precision medicine. Areas covered: The following article will highlight the intellectual property ('IP') considerations pertinent to molecular diagnostics development with special emphasis on companion diagnostics. Expert opinion/commentary Summary: For all molecular diagnostics, intellectual property (IP) concerns are of paramount concern, whether the device will be marketed only in the United States or abroad. Taking steps to protect IP at each stage of product development is critical to optimize profitability of a diagnostic product. Also the legal framework around IP protection of diagnostic technologies has been changing over the previous few years and can be expected to continue to change in the foreseeable near future, thus, a comprehensive IP strategy should take into account the fact that changes in the law can be expected.

  7. Best practice guidelines for the use of next-generation sequencing applications in genome diagnostics: a national collaborative study of dutch genome diagnostic laboratories

    NARCIS (Netherlands)

    Weiss, Marjan M.; van der Zwaag, Bert; Jongbloed, Jan D. H.; Vogel, Maartje J.; Brüggenwirth, Hennie T.; Lekanne Deprez, Ronald H.; Mook, Olaf; Ruivenkamp, Claudia A. L.; van Slegtenhorst, Marjon A.; van den Wijngaard, Arthur; Waisfisz, Quinten; Nelen, Marcel R.; van der Stoep, Nienke

    2013-01-01

    Next-generation sequencing (NGS) methods are being adopted by genome diagnostics laboratories worldwide. However, implementing NGS-based tests according to diagnostic standards is a challenge for individual laboratories. To facilitate the implementation of NGS in Dutch laboratories, the Dutch

  8. IERIAS: inference engine for reactor accident diagnostic system using knowledge engineering technique

    International Nuclear Information System (INIS)

    Yokobayashi, Masao; Yoshida, Kazuo; Kohsaka, Atsuo; Yamamoto, Minoru.

    1984-11-01

    This report describes an inference engine IERIAS which has been devoloped for a diagnostic system to identify the cause and type of an abnormal transient of a reactor plant. This system using knowledge engineering technique consists of a knowledge base and an inference engine. The inference engine IERIAS is designed so as to treat time-varying data of a plant. The major features of IERIAS are ; (1) histroy of transients can be treated, (2) knowledge base can be divided into some knowledge units, (3) program language UTILISP is used which is suitable for symbolic data manipulation. Inference was made using IERIAS with a knowledge base which was created from simulated results of various transients by a PWR plant simulator. The results showed a good applicability of IERIAS for reactor diagnosis. (author)

  9. Does the Reporting Quality of Diagnostic Test Accuracy Studies, as Defined by STARD 2015, Affect Citation?

    Science.gov (United States)

    Choi, Young Jun; Chung, Mi Sun; Koo, Hyun Jung; Park, Ji Eun; Yoon, Hee Mang; Park, Seong Ho

    2016-01-01

    To determine the rate with which diagnostic test accuracy studies that are published in a general radiology journal adhere to the Standards for Reporting of Diagnostic Accuracy Studies (STARD) 2015, and to explore the relationship between adherence rate and citation rate while avoiding confounding by journal factors. All eligible diagnostic test accuracy studies that were published in the Korean Journal of Radiology in 2011-2015 were identified. Five reviewers assessed each article for yes/no compliance with 27 of the 30 STARD 2015 checklist items (items 28, 29, and 30 were excluded). The total STARD score (number of fulfilled STARD items) was calculated. The score of the 15 STARD items that related directly to the Quality Assessment of Diagnostic Accuracy Studies (QUADAS)-2 was also calculated. The number of times each article was cited (as indicated by the Web of Science) after publication until March 2016 and the article exposure time (time in months between publication and March 2016) were extracted. Sixty-three articles were analyzed. The mean (range) total and QUADAS-2-related STARD scores were 20.0 (14.5-25) and 11.4 (7-15), respectively. The mean citation number was 4 (0-21). Citation number did not associate significantly with either STARD score after accounting for exposure time (total score: correlation coefficient = 0.154, p = 0.232; QUADAS-2-related score: correlation coefficient = 0.143, p = 0.266). The degree of adherence to STARD 2015 was moderate for this journal, indicating that there is room for improvement. When adjusted for exposure time, the degree of adherence did not affect the citation rate.

  10. Dose the reporting quality of diagnostic test accuracy studies, as defined by STARD 2015, affect citation?

    International Nuclear Information System (INIS)

    Choi, Young Jun; Chung, Mi Sun; Koo, Hyun Jung; Park, Ji Eun; Yoon, Hee Mang; Park, Seong Ho

    2016-01-01

    To determine the rate with which diagnostic test accuracy studies that are published in a general radiology journal adhere to the Standards for Reporting of Diagnostic Accuracy Studies (STARD) 2015, and to explore the relationship between adherence rate and citation rate while avoiding confounding by journal factors. All eligible diagnostic test accuracy studies that were published in the Korean Journal of Radiology in 2011–2015 were identified. Five reviewers assessed each article for yes/no compliance with 27 of the 30 STARD 2015 checklist items (items 28, 29, and 30 were excluded). The total STARD score (number of fulfilled STARD items) was calculated. The score of the 15 STARD items that related directly to the Quality Assessment of Diagnostic Accuracy Studies (QUADAS)-2 was also calculated. The number of times each article was cited (as indicated by the Web of Science) after publication until March 2016 and the article exposure time (time in months between publication and March 2016) were extracted. Sixty-three articles were analyzed. The mean (range) total and QUADAS-2-related STARD scores were 20.0 (14.5–25) and 11.4 (7–15), respectively. The mean citation number was 4 (0–21). Citation number did not associate significantly with either STARD score after accounting for exposure time (total score: correlation coefficient = 0.154, p = 0.232; QUADAS-2-related score: correlation coefficient = 0.143, p = 0.266). The degree of adherence to STARD 2015 was moderate for this journal, indicating that there is room for improvement. When adjusted for exposure time, the degree of adherence did not affect the citation rate

  11. Dose the reporting quality of diagnostic test accuracy studies, as defined by STARD 2015, affect citation?

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Young Jun; Chung, Mi Sun; Koo, Hyun Jung; Park, Ji Eun; Yoon, Hee Mang; Park, Seong Ho [Dept. of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul (Korea, Republic of)

    2016-09-15

    To determine the rate with which diagnostic test accuracy studies that are published in a general radiology journal adhere to the Standards for Reporting of Diagnostic Accuracy Studies (STARD) 2015, and to explore the relationship between adherence rate and citation rate while avoiding confounding by journal factors. All eligible diagnostic test accuracy studies that were published in the Korean Journal of Radiology in 2011–2015 were identified. Five reviewers assessed each article for yes/no compliance with 27 of the 30 STARD 2015 checklist items (items 28, 29, and 30 were excluded). The total STARD score (number of fulfilled STARD items) was calculated. The score of the 15 STARD items that related directly to the Quality Assessment of Diagnostic Accuracy Studies (QUADAS)-2 was also calculated. The number of times each article was cited (as indicated by the Web of Science) after publication until March 2016 and the article exposure time (time in months between publication and March 2016) were extracted. Sixty-three articles were analyzed. The mean (range) total and QUADAS-2-related STARD scores were 20.0 (14.5–25) and 11.4 (7–15), respectively. The mean citation number was 4 (0–21). Citation number did not associate significantly with either STARD score after accounting for exposure time (total score: correlation coefficient = 0.154, p = 0.232; QUADAS-2-related score: correlation coefficient = 0.143, p = 0.266). The degree of adherence to STARD 2015 was moderate for this journal, indicating that there is room for improvement. When adjusted for exposure time, the degree of adherence did not affect the citation rate.

  12. Thermoeconomic studies applied to maintenance of power plants

    International Nuclear Information System (INIS)

    Carvalho, F.R.; Horta Nogueira, L.A.

    1996-01-01

    The thermoeconomic method is an important tool aiming to improve maintenance activities in steam power plants, becoming possible to share the irreversibilities costs to each equipment, as boilers, turbines and heat exchangers. Furthermore, the effects related to changes in operational and design parameters can be studied in a detailed way, evaluating the local and distributed effects. In this work, after a brief review of power plant maintenance costs concepts and values, one address a methodology for maintenance costs estimation and develops a case study of thermoeconomics of a hypothetical plant, presenting the exergy flows, exergy losses and maintenance costs distribution. Also is presented an evaluation of exergoeconomic maintenance cost, evaluating their significance, at equipment level, related to overall maintenance cost, aiming to help the maintenance activities planning. 10 refs, 3 figs, 12 tabs

  13. A comparative study of quality control in diagnostic radiology

    International Nuclear Information System (INIS)

    Kharita, M. H.; Khedr, M.S.; Wannus, K.M.

    2008-01-01

    The main objective of this comparative study was to evaluate the national quality assurance program for X-ray diagnostic radiology in Syrian governmental hospitals. Two periods were covered in this study, the first period was from 1986 to 1998 (52 hospitals and 149 X-ray machines were considered) and the second period from 1999 to 2005 (41 hospitals and 95 X-ray machines were considered). Most of the X-ray machines studied were within the acceptable performance, but few machines needed recalibration for some parameters. Considerable improvement of about 50% was reported in the second period. This improvement could be attributed to the establishment of an effective National Regulatory Authority in Syria in 1998 that introduced and gradually enforced the quality assurance requirement for X-ray equipment as part of the licensing process and to the relatively newer X-ray machines covered in the second period. The Author 2008. Published by Oxford Univ. Press. All rights reserved. (authors)

  14. A Study on Soft Computing Applications in I and C Systems of Nuclear Power Plant

    International Nuclear Information System (INIS)

    Kang, H. T.; Chung, H. Y.

    2006-01-01

    In the paper, the application of the soft computing based nuclear power plant(NPP) is discussed. Soft computing such as neural network(NN), fuzzy logic controller(FLC), and genetic algorithm(GA) and/or their hybrid will be a new frontier for the development of instrument and control(I and C) systems in NPP. The application includes several fields, for example, the diagnostics of system transient, optimal data selection in NN, and intelligent control etc. Two or more combining structure, hybrid system, is more efficient. The concept of FLC, NN, and GA is presented in Section 2. The applications of soft computing used in NPP are presented in Section 3

  15. Application of positron emitters to studies on plants

    Energy Technology Data Exchange (ETDEWEB)

    Ishioka, N S; Matsuoka, H [Japan Atomic Energy Research Inst., Takasaki, Gunma (Japan). Takasaki Radiation Chemistry Research Establishment; Sekine, T [and others

    1998-10-01

    A newly developed positron emitting tracer imaging system enables us to study dynamically the physiological function of plants, although this system covers, at present, a limited area in a plant. Production of the positron emitters {sup 11}C, {sup 13}N, {sup 18}F and {sup 48}V for this application, using an AVF cyclotron, is described. (author)

  16. Comparative studies between nuclear power plants and hydroelectric power plants

    International Nuclear Information System (INIS)

    Menegassi, J.

    1984-01-01

    This paper shows the quantitative evolution of the power plants in the main countries of the world. The Brazilian situation is analysed, with emphasys in the technical and economical aspects related to power production by hidroelectric or nuclear power plants. The conclusion is that the electricity produced by hidro power plants becomes not economics when is intended to be produced at large distances from the demand centers. (Author) [pt

  17. A modular multi-microcomputer system for on-line vibration diagnostics

    International Nuclear Information System (INIS)

    Saedtler, E.

    1988-01-01

    A new modular multi-microprocessor system for on-line vibration monitoring and diagnostics of PWRs is described. The aim of the system is to make feasible an early detection of increasing failures in relevant regions of a reactor plant, to verify the mechanical integrity of the investigated components, and to improve therefore the operational safety of the plant. After a discussion of the implemented surveillance methods and algorithms, which are based on hierarchical structured identification (estimation) and statistical pattern recognition tools, the system architecture (software and hardware) is portrayed. The classification scheme itself works sequential so that samples (or features) can arrive on-line. This on-line classification is important in order to take necessary actions in time. Furthermore, the system has learning capabilities, which means it is adaptable to different, varying states and plant conditions. The main features of the system are presented and its contribution to an automation of complex surveillance and monitoring tasks is shown. (author)

  18. Literature study of plants diversity in Sempu Island Nature Reserve, East Java

    Directory of Open Access Journals (Sweden)

    RONY IRAWANTO

    2017-03-01

    Full Text Available Abstract. Irawanto R, Abywijaya IK, Mudiana D. 2017. Literature study of plants diversity in Sempu Island Nature Reserve, East Java. Pros Sem Nas Masy Biodiv Indon 3: 138-146. Purwodadi Botanic Garden have the task of plant conservation through inventories, exploration, collection and maintenance of plants, especially on dry lowland plants. Exploration activities and plants collection aim to conserve and save the plants from extinction, as well as conduct research and documentation of plant diversity in a region. It's related of the global strategy for plant conservation (GSPC target is known and documentation of plants diversity, especially in threatened habitats could be a priority. Sempu island's status as a nature reserve has a diversity of ecosystem and biodiversity of flora and fauna that are endemic and unique. This study aims to determine the plant's diversity in Island Sempu Nature Reserve based on a literature review of various studies that have been done. This study is a database for planning exploration activities, collecting, and documenting the plant's diversity in Sempu Island - East Java. Based on the literature review there are 282 species of plant diversity in Sempu Island, included in 80 families, contained in 10 blocks/location areas, namely Telaga Lele, Telaga Sat, Telaga Dowo, Gladakan, Baru-baru, Gua Macan, Teluk Ra’as, Teluk Semut, Air Tawar, dan Waru-Waru.Tenth blocks represent plants vegetation of mangrove forest, coastal forest, lowland tropical forests, and meadows.

  19. Diagnostic value of eosinophils in pleural effusion: a prospective study of 26 cases.

    Science.gov (United States)

    Matthai, Smita Mary; Kini, Usha

    2003-02-01

    Eosinophilic pleural effusions (EPFs), defined as the presence of 10% or more eosinophils in the pleural fluid, are relatively rare. Their diagnostic and prognostic significance, however, remains controversial, as most of the studies are based almost entirely on retrospective case studies. This prospective study examines 26 eosinophilic pleural effusions from among 444 consecutive pleural effusions investigated at this tertiary health care center from October 1999 to April 2002. This study was attempted to unravel the diagnostic and prognostic significance of these eosinophilic effusions and assess their clinical implications, if any. Koss and Light's criteria were applied in the analysis, which comprised macroscopic, biochemical, cytological, and microbiological examinations. Of the 26 EPFs studied, five were associated with tuberculosis and three with metastatic disease. Nineteen patients had significant associated lymphocytosis. Twenty-four patients have been followed up and are in good health to date and have had no recurrence of effusion. Thus, EPF could be associated with inflammatory, benign, and malignant conditions. Hence, a closer search for a definite etiological agent is warranted in the setting of such an effusion, especially in populations endemic for tuberculosis, as in a developing country like India and in populations with a high prevalence of malignancy. Copyright 2003 Wiley-Liss, Inc.

  20. Proposed Diagnostic Criteria for Smartphone Addiction.

    Science.gov (United States)

    Lin, Yu-Hsuan; Chiang, Chih-Lin; Lin, Po-Hsien; Chang, Li-Ren; Ko, Chih-Hung; Lee, Yang-Han; Lin, Sheng-Hsuan

    2016-01-01

    Global smartphone penetration has led to unprecedented addictive behaviors. The aims of this study are to develop diagnostic criteria of smartphone addiction and to examine the discriminative ability and the validity of the diagnostic criteria. We developed twelve candidate criteria for characteristic symptoms of smartphone addiction and four criteria for functional impairment caused by excessive smartphone use. The participants consisted of 281 college students. Each participant was systematically assessed for smartphone-using behaviors by psychiatrist's structured diagnostic interview. The sensitivity, specificity, and diagnostic accuracy of the candidate symptom criteria were analyzed with reference to the psychiatrists' clinical global impression. The optimal model selection with its cutoff point of the diagnostic criteria differentiating the smartphone addicted subjects from non-addicted subjects was then determined by the best diagnostic accuracy. Six symptom criteria model with optimal cutoff point were determined based on the maximal diagnostic accuracy. The proposed smartphone addiction diagnostic criteria consisted of (1) six symptom criteria, (2) four functional impairment criteria and (3) exclusion criteria. Setting three symptom criteria as the cutoff point resulted in the highest diagnostic accuracy (84.3%), while the sensitivity and specificity were 79.4% and 87.5%, respectively. We suggested determining the functional impairment by two or more of the four domains considering the high accessibility and penetration of smartphone use. The diagnostic criteria of smartphone addiction demonstrated the core symptoms "impaired control" paralleled with substance related and addictive disorders. The functional impairment involved multiple domains provide a strict standard for clinical assessment.

  1. Proposed Diagnostic Criteria for Smartphone Addiction.

    Directory of Open Access Journals (Sweden)

    Yu-Hsuan Lin

    Full Text Available Global smartphone penetration has led to unprecedented addictive behaviors. The aims of this study are to develop diagnostic criteria of smartphone addiction and to examine the discriminative ability and the validity of the diagnostic criteria.We developed twelve candidate criteria for characteristic symptoms of smartphone addiction and four criteria for functional impairment caused by excessive smartphone use. The participants consisted of 281 college students. Each participant was systematically assessed for smartphone-using behaviors by psychiatrist's structured diagnostic interview. The sensitivity, specificity, and diagnostic accuracy of the candidate symptom criteria were analyzed with reference to the psychiatrists' clinical global impression. The optimal model selection with its cutoff point of the diagnostic criteria differentiating the smartphone addicted subjects from non-addicted subjects was then determined by the best diagnostic accuracy.Six symptom criteria model with optimal cutoff point were determined based on the maximal diagnostic accuracy. The proposed smartphone addiction diagnostic criteria consisted of (1 six symptom criteria, (2 four functional impairment criteria and (3 exclusion criteria. Setting three symptom criteria as the cutoff point resulted in the highest diagnostic accuracy (84.3%, while the sensitivity and specificity were 79.4% and 87.5%, respectively. We suggested determining the functional impairment by two or more of the four domains considering the high accessibility and penetration of smartphone use.The diagnostic criteria of smartphone addiction demonstrated the core symptoms "impaired control" paralleled with substance related and addictive disorders. The functional impairment involved multiple domains provide a strict standard for clinical assessment.

  2. A Comparative Study on Diagnostic Accuracy of Colour Coded Digital Images, Direct Digital Images and Conventional Radiographs for Periapical Lesions – An In Vitro Study

    Science.gov (United States)

    Mubeen; K.R., Vijayalakshmi; Bhuyan, Sanat Kumar; Panigrahi, Rajat G; Priyadarshini, Smita R; Misra, Satyaranjan; Singh, Chandravir

    2014-01-01

    Objectives: The identification and radiographic interpretation of periapical bone lesions is important for accurate diagnosis and treatment. The present study was undertaken to study the feasibility and diagnostic accuracy of colour coded digital radiographs in terms of presence and size of lesion and to compare the diagnostic accuracy of colour coded digital images with direct digital images and conventional radiographs for assessing periapical lesions. Materials and Methods: Sixty human dry cadaver hemimandibles were obtained and periapical lesions were created in first and second premolar teeth at the junction of cancellous and cortical bone using a micromotor handpiece and carbide burs of sizes 2, 4 and 6. After each successive use of round burs, a conventional, RVG and colour coded image was taken for each specimen. All the images were evaluated by three observers. The diagnostic accuracy for each bur and image mode was calculated statistically. Results: Our results showed good interobserver (kappa > 0.61) agreement for the different radiographic techniques and for the different bur sizes. Conventional Radiography outperformed Digital Radiography in diagnosing periapical lesions made with Size two bur. Both were equally diagnostic for lesions made with larger bur sizes. Colour coding method was least accurate among all the techniques. Conclusion: Conventional radiography traditionally forms the backbone in the diagnosis, treatment planning and follow-up of periapical lesions. Direct digital imaging is an efficient technique, in diagnostic sense. Colour coding of digital radiography was feasible but less accurate however, this imaging technique, like any other, needs to be studied continuously with the emphasis on safety of patients and diagnostic quality of images. PMID:25584318

  3. Comparing the relative cost-effectiveness of diagnostic studies: a new model

    International Nuclear Information System (INIS)

    Patton, D.D.; Woolfenden, J.M.; Wellish, K.L.

    1986-01-01

    We have developed a model to compare the relative cost-effectiveness of two or more diagnostic tests. The model defines a cost-effectiveness ratio (CER) for a diagnostic test as the ratio of effective cost to base cost, only dollar costs considered. Effective cost includes base cost, cost of dealing with expected side effects, and wastage due to imperfect test performance. Test performance is measured by diagnostic utility (DU), a measure of test outcomes incorporating the decision-analytic variables sensitivity, specificity, equivocal fraction, disease probability, and outcome utility. Each of these factors affecting DU, and hence CER, is a local, not universal, value; these local values strongly affect CER, which in effect becomes a property of the local medical setting. When DU = +1 and there are no adverse effects, CER = 1 and the patient benefits from the test dollar for dollar. When there are adverse effects effective cost exceeds base cost, and for an imperfect test DU 1. As DU approaches 0 (worthless test), CER approaches infinity (no effectiveness at any cost). If DU is negative, indicating that doing the test at all would be detrimental, CER also becomes negative. We conclude that the CER model is a useful preliminary method for ranking the relative cost-effectiveness of diagnostic tests, and that the comparisons would best be done using local values; different groups might well arrive at different rankings. (Author)

  4. Progress in diagnostics of the COMPASS tokamak

    Science.gov (United States)

    Weinzettl, V.; Adamek, J.; Berta, M.; Bilkova, P.; Bogar, O.; Bohm, P.; Cavalier, J.; Dejarnac, R.; Dimitrova, M.; Ficker, O.; Fridrich, D.; Grover, O.; Hacek, P.; Havlicek, J.; Havranek, A.; Horacek, J.; Hron, M.; Imrisek, M.; Komm, M.; Kovarik, K.; Krbec, J.; Markovic, T.; Matveeva, E.; Mitosinkova, K.; Mlynar, J.; Naydenkova, D.; Panek, R.; Paprok, R.; Peterka, M.; Podolnik, A.; Seidl, J.; Sos, M.; Stockel, J.; Tomes, M.; Varavin, M.; Varju, J.; Vlainic, M.; Vondracek, P.; Zajac, J.; Zacek, F.; Stano, M.; Anda, G.; Dunai, D.; Krizsanoczi, T.; Refy, D.; Zoletnik, S.; Silva, A.; Gomes, R.; Pereira, T.; Popov, Tsv.; Sarychev, D.; Ermak, G. P.; Zebrowski, J.; Jakubowski, M.; Rabinski, M.; Malinowski, K.; Nanobashvili, S.; Spolaore, M.; Vianello, N.; Gauthier, E.; Gunn, J. P.; Devitre, A.

    2017-12-01

    The COMPASS tokamak at IPP Prague is a small-size device with an ITER-relevant plasma geometry and operating in both the Ohmic as well as neutral beam assisted H-modes since 2012. A basic set of diagnostics installed at the beginning of the COMPASS operation has been gradually broadened in type of diagnostics, extended in number of detectors and collected channels and improved by an increased data acquisition speed. In recent years, a significant progress in diagnostic development has been motivated by the improved COMPASS plasma performance and broadening of its scientific programme (L-H transition and pedestal scaling studies, magnetic perturbations, runaway electron control and mitigation, plasma-surface interaction and corresponding heat fluxes, Alfvenic and edge localized mode observations, disruptions, etc.). In this contribution, we describe major upgrades of a broad spectrum of the COMPASS diagnostics and discuss their potential for physical studies. In particular, scrape-off layer plasma diagnostics will be represented by a new concept for microsecond electron temperature and heat flux measurements - we introduce a new set of divertor Langmuir and ball-pen probe arrays, newly constructed probe heads for reciprocating manipulators as well as several types of standalone probes. Among optical tools, an upgraded high-resolution edge Thomson scattering diagnostic for pedestal studies and a set of new visible light and infrared (plasma-surface interaction investigations) cameras will be described. Particle and beam diagnostics will be covered by a neutral particle analyzer, diagnostics on a lithium beam, Cherenkov detectors (for a direct detection of runaway electrons) and neutron detectors. We also present new modifications of the microwave reflectometer for fast edge density profile measurements.

  5. Veterinary Molecular Diagnostics

    NARCIS (Netherlands)

    Roest, H.I.J.; Engelsma, M.Y.; Weesendorp, E.; Bossers, A.; Elbers, A.R.W.

    2017-01-01

    In veterinary molecular diagnostics, samples originating from animals are tested. Developments in the farm animals sector and in our societal attitude towards pet animals have resulted in an increased demand for fast and reliable diagnostic techniques. Molecular diagnostics perfectly matches this

  6. Methanol plant ship: implementation study. Export trade information

    International Nuclear Information System (INIS)

    1988-01-01

    The study compiled the economic, commercial and financing requirements of a floating plant ship with a production capacity of 3,000 tons of methanol a day. The raw material for the methanol production would be supplied from a natural gas reserve off the coast of Trinidad. The report has a separate section for each aspect of the plant ship project, such as methanol storage; logistics of transporting methanol to the United States; the required sub-sea installation to bring natural gas to the plant ship; and plant ship design and equipment. It gives a detailed description of a proposed organizational structure and its tax consequences. The project's financial requirements and economic impact are examined. The environmental consequences and other operator issues are analyzed. Tables and figures accompany the report

  7. Aquatic Plant Control Research Program. Allelopathic Aquatic Plants for Aquatic Plant Management: A Feasibility Study

    Science.gov (United States)

    1989-10-01

    1978. " Ecotoxicology of aquatic plant communi- ties," Principles of Ecotoxicology , SCOPE Report 12, Chapter 11, pp 239-255. [Heavy metals, Pollutants...Phragmites communis and Equisetum limosum were cultivated . They found plant-plant influences depend on soil type. Typha latifolia, S. A2 lacustris, and

  8. Proposed diagnostic criteria for internet addiction.

    Science.gov (United States)

    Tao, Ran; Huang, Xiuqin; Wang, Jinan; Zhang, Huimin; Zhang, Ying; Li, Mengchen

    2010-03-01

    The objective of this study was to develop diagnostic criteria for internet addiction disorder (IAD) and to evaluate the validity of our proposed diagnostic criteria for discriminating non-dependent from dependent internet use in the general population. This study was conducted in three stages: the developmental stage (110 subjects in the survey group; 408 subjects in the training group), where items of the proposed diagnostic criteria were developed and tested; the validation stage (n = 405), where the proposed criteria were evaluated for criterion-related validity; and the clinical stage (n = 150), where the criteria and the global clinical impression of IAD were evaluated by more than one psychiatrist to determine inter-rater reliability. The proposed internet addiction diagnostic criteria consisted of symptom criterion (seven clinical symptoms of IAD), clinically significant impairment criterion (functional and psychosocial impairments), course criterion (duration of addiction lasting at least 3 months, with at least 6 hours of non-essential internet usage per day) and exclusion criterion (exclusion of dependency attributed to psychotic disorders). A diagnostic score of 2 + 1, where the first two symptoms (preoccupation and withdrawal symptoms) and at least one of the five other symptoms (tolerance, lack of control, continued excessive use despite knowledge of negative effects/affects, loss of interests excluding internet, and use of the internet to escape or relieve a dysphoric mood) was established. Inter-rater reliability was 98%. Our findings suggest that the proposed diagnostic criteria may be useful for the standardization of diagnostic criteria for IAD.

  9. Application of forwardchaining method to diagnosis of onion plant diseases

    Science.gov (United States)

    Sitanggang, Delima; Siregar, Saut D.; Situmeang, Suryani M. F.; Indra, Evta; Sagala, Ayu R.; Sihombing, Oloan; Nababan, Marlince; Pasaribu, Hendra; Damanik, Rudolf R.; Turnip, Mardi; Saragih, Rijois I. E.

    2018-04-01

    Red Onion is a tuber plant that is widely used by the people of Indonesia, both as herbs and herbal medicines. Onion farmers have limitations in identifying diseases that attack their crops.This disease can cause crop failure against the onion.This design begins with the creation of a knowledge base up to input-output design with forward chaining method. The results of this design can assist farmers in identifying their plant diseases. Based on diagnostic results of several methods that have been done testing can diagnose diseases contained in onion plants. With symptoms data that has been determined by the expert with the value of each symptom is different. As for the symptoms that have been determined that the leaves contain patches with a value of 0.3, White leaf spots value 0.4, Leaf spots form a purple zone if it is severe 0.5, Leaf tip of 0.2, Tubers rot 0.4. Based on the above diagnostic results then get the value of diagnosis 67% forward chaining with trotol disease type, Purple spotting.

  10. An investigation of diagnostic accuracy and confidence related to diagnostic checklists as well as gender biases in relation to mental disorders

    Directory of Open Access Journals (Sweden)

    Jan Christopher Cwik

    2016-11-01

    Full Text Available This study examines the utility of checklists in attaining more accurate diagnoses in the context of diagnostic decision-making for mental disorders. The study also aimed to replicate results from a meta-analysis indicating that there is no association between patients’ gender and misdiagnoses. To this end, 475 psychotherapists were asked to judge three case vignettes describing patients with Major Depressive Disorder, Generalized Anxiety Disorder, and Borderline Personality Disorder. Therapists were randomly assigned to experimental conditions in a 2 (diagnostic method: with using diagnostic checklists vs. without using diagnostic checklists x 2 (gender: male vs. female case vignettes between-subjects design. Multinomial logistic and linear regression analyses were used to examine the association between the usage of diagnostic checklists as well as patients’ gender and diagnostic decisions.The results showed that when checklists were used, fewer incorrect co-morbid diagnoses were made, but clinicians were less likely to diagnose MDD even when the criteria were met. Additionally, checklists improved therapists’ confidence with diagnostic decisions, but were not associated with estimations of patients’ characteristics. As expected, there were no significant associations between gender and diagnostic decisions.

  11. An Investigation of Diagnostic Accuracy and Confidence Associated with Diagnostic Checklists as Well as Gender Biases in Relation to Mental Disorders.

    Science.gov (United States)

    Cwik, Jan C; Papen, Fabienne; Lemke, Jan-Erik; Margraf, Jürgen

    2016-01-01

    This study examines the utility of checklists in attaining more accurate diagnoses in the context of diagnostic decision-making for mental disorders. The study also aimed to replicate results from a meta-analysis indicating that there is no association between patients' gender and misdiagnoses. To this end, 475 psychotherapists were asked to judge three case vignettes describing patients with Major Depressive Disorder (MDD), Generalized Anxiety Disorder, and Borderline Personality Disorder. Therapists were randomly assigned to experimental conditions in a 2 (diagnostic method: with using diagnostic checklists vs. without using diagnostic checklists) × 2 (gender: male vs. female case vignettes) between-subjects design. Multinomial logistic and linear regression analyses were used to examine the association between the usage of diagnostic checklists as well as patients' gender and diagnostic decisions. The results showed that when checklists were used, fewer incorrect co-morbid diagnoses were made, but clinicians were less likely to diagnose MDD even when the criteria were met. Additionally, checklists improved therapists' confidence with diagnostic decisions, but were not associated with estimations of patients' characteristics. As expected, there were no significant associations between gender and diagnostic decisions.

  12. Plasma Diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Zaveryaev, V [Kurchatov Institute, Moscow (Russian Federation); others, and

    2012-09-15

    The success in achieving peaceful fusion power depends on the ability to control a high temperature plasma, which is an object with unique properties, possibly the most complicated object created by humans. Over years of fusion research a new branch of science has been created, namely plasma diagnostics, which involves knowledge of almost all fields of physics, from electromagnetism to nuclear physics, and up-to-date progress in engineering and technology (materials, electronics, mathematical methods of data treatment). Historically, work on controlled fusion started with pulsed systems and accordingly the methods of plasma parameter measurement were first developed for short lived and dense plasmas. Magnetically confined hot plasmas require the creation of special experimental techniques for diagnostics. The diagnostic set is the most scientifically intensive part of a plasma device. During many years of research operation some scientific tasks have been solved while new ones arose. New tasks often require significant changes in the diagnostic system, which is thus a very flexible part of plasma machines. Diagnostic systems are designed to solve several tasks. As an example here are the diagnostic tasks for the International Thermonuclear Experimental Reactor - ITER: (1) Measurements for machine protection and basic control; (2) Measurements for advanced control; (3) Additional measurements for performance evaluation and physics. Every new plasma machine is a further step along the path to the main goal - controlled fusion - and nobody knows in advance what new phenomena will be met on the way. So in the planning of diagnostic construction we should keep in mind further system upgrading to meet possible new scientific and technical challenges. (author)

  13. Barnwell Nuclear Fuels Plant applicability study. Executive summary

    International Nuclear Information System (INIS)

    1978-04-01

    A study was conducted of the Barnwell Nuclear Fuels Plant in South Carolina to determine if that facility can be utilized in support of the nonproliferation objectives of the United States; and for activities contributing to the International Nuclear Fuel Cycle Evaluation to be carried out under contract at the Barnwell plant. One of the conclusions of this study is that there is nothing to support modification of the Presidential decision that the BNFP receive neither Federal encouragement nor funding for its completion on a reprocessing facility

  14. DU-AGG pilot plant design study

    International Nuclear Information System (INIS)

    Lessing, P.A.; Gillman, H.

    1996-07-01

    The Idaho National Engineering Laboratory (INEL) is developing new methods to produce high-density aggregate (artificial rock) primarily consisting of depleted uranium oxide. The objective is to develop a low-cost method whereby uranium oxide powder (UO[sub 2], U[sub 3]O[sub ]8, or UO[sub 3]) can be processed to produce high-density aggregate pieces (DU-AGG) having physical properties suitable for disposal in low-level radioactive disposal facilities or for use as a component of high-density concrete used as shielding for radioactive materials. A commercial company, G-M Systems, conducted a design study for a manufacturing pilot plant to process DU-AGG. The results of that study are included and summarized in this report. Also explained are design considerations, equipment capacities, the equipment list, system operation, layout of equipment in the plant, cost estimates, and the proposed plan and schedule

  15. Plant systems/components modularization study. Final report. [PWR

    Energy Technology Data Exchange (ETDEWEB)

    1977-07-01

    The final results are summarized of a Plant Systems/Components Modularization Study based on Stone and Webster's Pressurized Water Reactor Reference Design. The program has been modified to include evaluation of the most promising areas for modular consideration based on the level of the Sundesert Project engineering design completion and the feasibility of their incorporation into the plant construction effort.

  16. Problems in calculating reactor model (primary circuit) for nuclear power plant diagnostics

    International Nuclear Information System (INIS)

    Markov, P.

    1986-01-01

    Some results are presented of the calculation of eigen-vibrations of the system of WWER-440 nuclear reactor vessels in a vacuum and in a liquid. Computer code BOSOR 4 has been written for calculating forced vibrations of shells with axial symmetry and of a simplified system of reactor vessels. A description is given of this code, which is based on the so-called energy method of finite differences. Briefly discussed is the feasibility of applying the results of the latest computation techniques in the diagnostics of the major components of a nuclear reactor. (Z.M.)

  17. Distress in suspected lung cancer patients following rapid and standard diagnostic programs: a prospective observational study.

    Science.gov (United States)

    Brocken, Pepijn; van der Heijden, Erik H F M; Oud, Karen T M; Bootsma, Gerben; Groen, Harry J M; Donders, A Rogier T; Dekhuijzen, P N Richard; Prins, Judith B

    2015-04-01

    Timeliness may influence emotional distress during the diagnostic phase of suspected lung cancer patients. We performed a prospective observational study to compare distress and quality of life (QoL) in two medical centres with a Rapid Outpatient Diagnostic Program (RODP) and two using conventional Stepwise Diagnostic Approach (SDA) on the basis of trained nurse-led care. Outpatients with radiological suspicion of lung cancer completed the Hospital Anxiety and Depression Scale (HADS), European Organization for Research and Treatment of Cancer 30-item Quality of Life Questionnaire (QLQ-C30) and its 13-item Lung Cancer specific module (QLQ-LC13) upon first visit, 2 days later, thereafter weekly for 5 weeks and after 3 months. The 72 SDA patients and 121 RODP patients had a mean pre-diagnostic HADS-total score of 13.5 (SD 7.6); 63.4% had a score ≥10. Baseline QLQ-C30 global QoL was 61.6 (SD 22.7) exceeding reference values for lung cancer patients. Generalized least square models showed a significant centre by time interaction effect: during the first 6 weeks, HADS-total scores decreased in RODP patients (13.8-11.9) but sustained in SDA patients (13.1-13.6), whereas QoL showed no relevant changes. Times to diagnosis and discussion of therapy plan for RODP patients were 7 and 11 days shorter, respectively. Suspected lung cancer patients had high baseline distress levels. A decrease over time was found in RODP compared with SDA patients. QoL did not change relevantly. Albeit observational, these data indicate that patients experience less distress in rapid diagnostic programs than in stepwise diagnostic evaluation. Copyright © 2014 John Wiley & Sons, Ltd.

  18. Diagnostic suite neuro-fuzzy in an advanced alarm monitoring and predictive diagnostic system for rotating machinery

    International Nuclear Information System (INIS)

    Geruzzi, P.

    1999-01-01

    The 'Foxboro SCADA', former 'Automation Systems Division' of Nuovo Pignone, at the end of eighty years, has been involved in the development of a flexible and powerful Diagnostic System for Rotating Machinery designed and manufactured in other divisions of the Company. This system amalgamates, in a single computer, all the functionality nowadays necessary to correctly manage locally and remotely the Evolutionary Maintenance of rotating machines as well as the relevant plants. It's specially designed to plan preventive and emergency maintenance procedures and to help the maintenance staff/service in preventing the occurrence of failures or severe damage to complete turbo-machinery plant including turbine, compressor and other machines. The system is designed to supervise and to analyze the operating state of one or more turbo- machinery units such as turbo-compressors, turbo-generators and turbo-pumps giving an effective support to plan preventive and breakdown maintenance monitoring the performances of each turbo-group's element and analyzing a large number of thermodynamic and mechanical parameters related to high pressure turbines, low pressure turbines, combustion chambers, axial compressors and load (compressors, generators, and pumps). A brief presentation of the system is provided (author) (ml)

  19. Study design for concurrent development, assessment, and implemen