WorldWideScience

Sample records for planned core diagnostics

  1. National NIF Diagnostic Program Interim Management Plan

    International Nuclear Information System (INIS)

    Warner, B

    2002-01-01

    The National Ignition Facility (NIF) has the mission of supporting Stockpile Stewardship and Basic Science research in high-energy-density plasmas. To execute those missions, the facility must provide diagnostic instrumentation capable of observing and resolving in time events and radiation emissions characteristic of the plasmas of interest. The diagnostic instrumentation must conform to high standards of operability and reliability within the NIF environment. These exacting standards, together with the facility mission of supporting a diverse user base, has led to the need for a central organization charged with delivering diagnostic capability to the NIF. The National NIF Diagnostics Program (NNDP) has been set up under the aegis of the NIF Director to provide that organization authority and accountability to the wide user community for NIF. The funds necessary to perform the work of developing diagnostics for NIF will be allocated from the National NIF Diagnostics Program to the participating laboratories and organizations. The participating laboratories and organizations will design, build, and commission the diagnostics for NIF. Restricted availability of funding has had an adverse impact, unforeseen at the time of the original decision to projectize NIF Core Diagnostics Systems and Cryogenic Target Handing Systems, on the planning and initiation of these efforts. The purpose of this document is to provide an interim project management plan describing the organizational structure and management processes currently in place for NIF Core Diagnostics Systems. Preparation of a Program Execution Plan for NIF Core Diagnostics Systems has been initiated and a current draft is provided as Attachment 1 to this document. The National NIF Diagnostics Program Interim Management Plan provides a summary of primary design criteria and functional requirements, current organizational structure, tracking and reporting procedures, and current planning estimates of project scope

  2. Studies on WWER core diagnostics

    International Nuclear Information System (INIS)

    Lunin, G.L.; Mitin, V.I.; Bulavin, V.V.

    1987-01-01

    The reliability and safety of nuclear power plants have decisive meaning under the situation that nuclear power generation steadily increases, and among various measures aiming at ensuring the reliability and safety in the operation of nuclear power plants, the countermeasures for protecting reactor core, main process equipment and high pressure circuits from damage have the important role, and the monitoring of condition and the organization of forecast, which are carried out continuously or periodically during the operation of nuclear power stations using the diagnostic expert system specially developed for the purpose, are included in them. Such monitoring enables the early detection of mechanical damage, increase of vibration, defects caused during operation and so on in reactor cores and primary and secondary circuits, and the continuous watching of defect developments. Also boiling in a core is detected, the place of abnormality occurrence is identified, and the intensity and characteristics of boiling are determined, thus the occurrence of dangerous condition is prevented. The developments of an in-core monitoring system and noise diagnostic systems are reported. (Kako, I.)

  3. Location of core diagnostic information across various sequences in brain MRI and implications for efficiency of MRI scanner utilization.

    Science.gov (United States)

    Sharma, Aseem; Chatterjee, Arindam; Goyal, Manu; Parsons, Matthew S; Bartel, Seth

    2015-04-01

    Targeting redundancy within MRI can improve its cost-effective utilization. We sought to quantify potential redundancy in our brain MRI protocols. In this retrospective review, we aggregated 207 consecutive adults who underwent brain MRI and reviewed their medical records to document clinical indication, core diagnostic information provided by MRI, and its clinical impact. Contributory imaging abnormalities constituted positive core diagnostic information whereas absence of imaging abnormalities constituted negative core diagnostic information. The senior author selected core sequences deemed sufficient for extraction of core diagnostic information. For validating core sequences selection, four readers assessed the relative ease of extracting core diagnostic information from the core sequences. Potential redundancy was calculated by comparing the average number of core sequences to the average number of sequences obtained. Scanning had been performed using 9.4±2.8 sequences over 37.3±12.3 minutes. Core diagnostic information was deemed extractable from 2.1±1.1 core sequences, with an assumed scanning time of 8.6±4.8 minutes, reflecting a potential redundancy of 74.5%±19.1%. Potential redundancy was least in scans obtained for treatment planning (14.9%±25.7%) and highest in scans obtained for follow-up of benign diseases (81.4%±12.6%). In 97.4% of cases, all four readers considered core diagnostic information to be either easily extractable from core sequences or the ease to be equivalent to that from the entire study. With only one MRI lacking clinical impact (0.48%), overutilization did not seem to contribute to potential redundancy. High potential redundancy that can be targeted for more efficient scanner utilization exists in brain MRI protocols.

  4. Diagnostic planning in JT-60 project

    International Nuclear Information System (INIS)

    Matoba, Tohru; Suzuki, Yasuo; Funahashi, Akimasa; Itagaki, Tokiyoshi

    1977-08-01

    The diagnostic plans of JT-60 were made along with design of the main machine. Basic requirements of the diagnostic program are (1) multiple measurement of respective plasma parameters, (2) efficient usage of the discharge, (3) capable data acquisition system, (4) high reliability of the diagnostic equipments, and (5) systematic development of new diagnostic techniques. Dimensions of the diagnostic ports were determined in detailed design of the vacuum vessel, anticipating the possible diagnostic methods. The proposed diagnostic systems and the plans are shown in table and figures respectively. Problems in the diagnostics are also described. (auth.)

  5. Strategic planning in diagnostic imaging: meeting the challenge.

    Science.gov (United States)

    Lexa, Frank J

    2008-02-01

    The 21st century has raised new and significant challenges to the practice of diagnostic imaging. Radiologists will have to navigate a difficult path as they face threats from disruptive technologies, adverse demographic changes, pressures to limit reimbursement both from the public and from the private sectors, increased domestic and crossborder competition, and many others. Success in these trying times will require greater attention to strategic planning if we are to thrive and survive in radiology. Strategic planning and tactical implementation methodologies were reviewed, from Sun Tzu to the present day, for applicability to the needs of modern radiology groups. A framework for developing and implementing strategic plans was constructed to assist radiology leaders and groups in considering the spectrum of tasks, from gathering intelligence, to developing scenarios, to implementing and evaluating tactical plans. Strategy and tactics are too important to be ignored or left to others. They need to be core activities for all radiology leaders. Frameworks can be used to help in providing structure and rigour to strategic planning efforts at the department and group level.

  6. The ITER bolometer diagnostic: Status and plans

    International Nuclear Information System (INIS)

    Meister, H.; Giannone, L.; Horton, L. D.; Raupp, G.; Zeidner, W.; Grunda, G.; Kalvin, S.; Fischer, U.; Serikov, A.; Stickel, S.; Reichle, R.

    2008-01-01

    A consortium consisting of four EURATOM Associations has been set up to develop the project plan for the full development of the ITER bolometer diagnostic and to continue urgent R and D activities. An overview of the current status is given, including detector development, line-of-sight optimization, performance analysis as well as the design of the diagnostic components and their integration in ITER. This is complemented by the presentation of plans for future activities required to successfully implement the bolometer diagnostic, ranging from the detector development over diagnostic design and prototype testing to RH tools for calibration.

  7. Lesson Planning with the Common Core

    Science.gov (United States)

    Estes, Linda A.; McDuffie, Amy Roth; Tate, Cathie

    2014-01-01

    Planning a lesson can be similar to planning a road trip--a metaphor the authors use to describe how they applied research and theory to their lesson planning process. A map and mode of transportation, the Common Core State Standards for Mathematics (CCSSM) and textbooks as resources, can lead to desired destinations, such as students engaging in…

  8. Disaster and Contingency Planning for Scientific Shared Resource Cores.

    Science.gov (United States)

    Mische, Sheenah; Wilkerson, Amy

    2016-04-01

    Progress in biomedical research is largely driven by improvements, innovations, and breakthroughs in technology, accelerating the research process, and an increasingly complex collaboration of both clinical and basic science. This increasing sophistication has driven the need for centralized shared resource cores ("cores") to serve the scientific community. From a biomedical research enterprise perspective, centralized resource cores are essential to increased scientific, operational, and cost effectiveness; however, the concentration of instrumentation and resources in the cores may render them highly vulnerable to damage from severe weather and other disasters. As such, protection of these assets and the ability to recover from a disaster is increasingly critical to the mission and success of the institution. Therefore, cores should develop and implement both disaster and business continuity plans and be an integral part of the institution's overall plans. Here we provide an overview of key elements required for core disaster and business continuity plans, guidance, and tools for developing these plans, and real-life lessons learned at a large research institution in the aftermath of Superstorm Sandy.

  9. Determining the Optimal Number of Core Needle Biopsy Passes for Molecular Diagnostics.

    Science.gov (United States)

    Hoang, Nam S; Ge, Benjamin H; Pan, Lorraine Y; Ozawa, Michael G; Kong, Christina S; Louie, John D; Shah, Rajesh P

    2018-03-01

    The number of core biopsy passes required for adequate next-generation sequencing is impacted by needle cut, needle gauge, and the type of tissue involved. This study evaluates diagnostic adequacy of core needle lung biopsies based on number of passes and provides guidelines for other tissues based on simulated biopsies in ex vivo porcine organ tissues. The rate of diagnostic adequacy for pathology and molecular testing from lung biopsy procedures was measured for eight operators pre-implementation (September 2012-October 2013) and post-implementation (December 2013-April 2014) of a standard protocol using 20-gauge side-cut needles for ten core biopsy passes at a single academic hospital. Biopsy pass volume was then estimated in ex vivo porcine muscle, liver, and kidney using side-cut devices at 16, 18, and 20 gauge and end-cut devices at 16 and 18 gauge to estimate minimum number of passes required for adequate molecular testing. Molecular diagnostic adequacy increased from 69% (pre-implementation period) to 92% (post-implementation period) (p < 0.001) for lung biopsies. In porcine models, both 16-gauge end-cut and side-cut devices require one pass to reach the validated volume threshold to ensure 99% adequacy for molecular characterization, while 18- and 20-gauge devices require 2-5 passes depending on needle cut and tissue type. Use of 20-gauge side-cut core biopsy needles requires a significant number of passes to ensure diagnostic adequacy for molecular testing across all tissue types. To ensure diagnostic adequacy for molecular testing, 16- and 18-gauge needles require markedly fewer passes.

  10. Disaster and Contingency Planning for Scientific Shared Resource Cores

    Science.gov (United States)

    Wilkerson, Amy

    2016-01-01

    Progress in biomedical research is largely driven by improvements, innovations, and breakthroughs in technology, accelerating the research process, and an increasingly complex collaboration of both clinical and basic science. This increasing sophistication has driven the need for centralized shared resource cores (“cores”) to serve the scientific community. From a biomedical research enterprise perspective, centralized resource cores are essential to increased scientific, operational, and cost effectiveness; however, the concentration of instrumentation and resources in the cores may render them highly vulnerable to damage from severe weather and other disasters. As such, protection of these assets and the ability to recover from a disaster is increasingly critical to the mission and success of the institution. Therefore, cores should develop and implement both disaster and business continuity plans and be an integral part of the institution’s overall plans. Here we provide an overview of key elements required for core disaster and business continuity plans, guidance, and tools for developing these plans, and real-life lessons learned at a large research institution in the aftermath of Superstorm Sandy. PMID:26848285

  11. Pretreatment axillary ultrasonography and core biopsy in patients with suspected breast cancer: Diagnostic accuracy and impact on management

    Energy Technology Data Exchange (ETDEWEB)

    Garcia-Ortega, Maria Jose, E-mail: rserranogan@telefonica.net [Breast Imaging Center, Radiology Department, Hospital Universitario Reina Sofia, Avda. Menendez Pidal s/n, 14004 Cordoba (Spain); Alvarez Benito, Marina, E-mail: marinaalvarezbenito@telefonica.net [Breast Imaging Center, Radiology Department, Hospital Universitario Reina Sofia, Avda. Menendez Pidal s/n, 14004 Cordoba (Spain); Fuentes Vahamonde, Elena, E-mail: elena.fuentes.sspa@juntadeandalucia.es [Pathology Department, Hospital Universitario Reina Sofia, Avda. Menendez Pidal s/n, 14004 Cordoba (Spain); Rioja Torres, Pilar, E-mail: priojat@yahoo.es [Clinical Management Unit, Department of General and Digestive Surgery, Hospital Universitario Reina Sofia, Avda. Menendez Pidal s/n, 14004 Cordoba (Spain); Benitez Velasco, Ana, E-mail: abvelazco@yahoo.es [Nuclear Medicine Department, Hospital Universitario Reina Sofia, Avda. Menendez Pidal s/n, 14004 Cordoba (Spain); Martinez Paredes, Maria, E-mail: mariaparedes@uco.es [Radiology and Physical Medicine Area, University of Cordoba Medical School, Avda. Menendez Pidal s/n, 14004 Cordoba (Spain)

    2011-07-15

    Preoperative diagnosis of axillary metastases in breast cancer patients enables treatment planning. We aimed to evaluate the diagnostic accuracy of axillary ultrasonography and percutaneous biopsy, both alone and in combination, in detecting axillary metastases in patients with breast cancer and to assess the impact of these techniques on the patients' management. Materials and methods: Retrospective study of consecutive patients with suspected breast cancer examined between October 2006 and December 2008. The diagnosis of a primary tumor was histologically confirmed in all patients. All patients underwent axillary ultrasonography and percutaneous core biopsy (14G) of suspicious lymph nodes. We evaluated the morphological characteristics of the lymph nodes by ultrasonography. We calculated the diagnostic accuracy of ultrasonography and of core biopsy, and assessed the impact of these techniques on patients' treatment. Results: We evaluated 675 axillary regions and performed 291 core biopsies of axillary lymph nodes in 662 patients. In 650 patients, breast cancer was histologically confirmed and in 12 patients malignant tumors in other locations were confirmed. The sensitivity and specificity of axillary ultrasonography were 63.2% and 88.7%, respectively. The absence of a fatty hilum within the lymph node was the ultrasonographic finding with the highest positive predictive value for malignancy (93.1%). The sensitivity and specificity of axillary core biopsy were 69.1% and 100%, respectively. Sentinel lymph node biopsy was avoided in 33% of initial candidates and immediate breast reconstruction was undertaken in 35.1% of the patients with mastectomy and negative axillary core biopsy. Conclusions: Ultrasonography and axillary core biopsy enable adequate pretreatment staging in patients with breast cancer and has a positive impact on their management.

  12. An Advanced Diagnostic Display for Core Protection Calculator System

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Ji-Hyeon; Jeong, See-Chae; Sohn, Se-Do [Korea Power Engineering Company, Daejeon (Korea, Republic of)

    2008-10-15

    The main purpose of a Nuclear Power Plant Instrumentation and Control (I and C) Display System is to provide operator's interface for I and C systems. The CPCS display(Shin-Kori 1 and 2) provides operators with 1) plant monitoring values of field input and algorithm variables that reflect the reactor core conditions, 2) operation values that operators can change and 3) CPCS status. It will be an optimal case if operators can understand the plant (including CPCS itself) condition intuitively with the displayed values but it is not easy in CPCS. For example, if the CPCS Channel Trouble light is lit, operators need some amount of time to investigate what caused the trouble light because there are more than hundred causes that can generate the channel trouble. If a Display supports diagnostic information that shows what cause the displayed alarms, it will greatly help operators in easy understanding the CPCS status. To provide these diagnostic information, this paper suggests an active self-explanatory display mechanism. This self-explanatory diagnostic display mechanism utilizes an ontology in XML that describes parent child, sibling relationships of display variables, through which in-depth, in-breadth diagnostic tracking is possible. This paper consists of two parts. First, the key features of CPCS Flat Panel Display System (FPDS) are described. Second, the features of active self explanatory diagnostic display are discussed.

  13. An Advanced Diagnostic Display for Core Protection Calculator System

    International Nuclear Information System (INIS)

    Kim, Ji-Hyeon; Jeong, See-Chae; Sohn, Se-Do

    2008-01-01

    The main purpose of a Nuclear Power Plant Instrumentation and Control (I and C) Display System is to provide operator's interface for I and C systems. The CPCS display(Shin-Kori 1 and 2) provides operators with 1) plant monitoring values of field input and algorithm variables that reflect the reactor core conditions, 2) operation values that operators can change and 3) CPCS status. It will be an optimal case if operators can understand the plant (including CPCS itself) condition intuitively with the displayed values but it is not easy in CPCS. For example, if the CPCS Channel Trouble light is lit, operators need some amount of time to investigate what caused the trouble light because there are more than hundred causes that can generate the channel trouble. If a Display supports diagnostic information that shows what cause the displayed alarms, it will greatly help operators in easy understanding the CPCS status. To provide these diagnostic information, this paper suggests an active self-explanatory display mechanism. This self-explanatory diagnostic display mechanism utilizes an ontology in XML that describes parent child, sibling relationships of display variables, through which in-depth, in-breadth diagnostic tracking is possible. This paper consists of two parts. First, the key features of CPCS Flat Panel Display System (FPDS) are described. Second, the features of active self explanatory diagnostic display are discussed

  14. TMI-2 core examination plan

    International Nuclear Information System (INIS)

    Carlson, J.O.

    1984-07-01

    The role of the Three Mile Island Unit 2 (TMI-2) core examination in the resolution of major nuclear safety issues is delineated in this plan. Relevant data needs are discussed, and approaches for recovering data from the TMI-2 plant are identified. Specific recommendations and justifications are provided for in situ documentation and off-site artifact examination activities. The research and development program is being managed by EG and G Idaho, Inc

  15. Integrated Program of Experimental Diagnostics at the NNSS: An Integrated, Prioritized Work Plan for Diagnostic Development and Maintenance and Supporting Capability

    International Nuclear Information System (INIS)

    2010-01-01

    This Integrated Program of Experimental Diagnostics at the NNSS is an integrated prioritized work plan for the Nevada National Security Site (NNSS), formerly the Nevada Test Site (NTS), program that is independent of individual National Security Enterprise Laboratories (Labs) requests or specific Subprograms being supported. This prioritized work plan is influenced by national priorities presented in the Predictive Capability Framework (PCF) and other strategy documents (Primary and Secondary Assessment Technologies Plans and the Plutonium Experiments Plan). This document satisfies completion criteria for FY 2010 MRT milestone No.3496: Document an integrated, prioritized work plan for diagnostic development, maintenance, and supporting capability. This document is an update of the 3-year NNSS plan written a year ago, September 21, 2009, to define and understand Lab requests for diagnostic implementation. This plan is consistent with Lab interpretations of the PCF, Primary Assessment Technologies, and Plutonium Experiment plans.

  16. Diagnostic accuracy of 22/25-gauge core needle in endoscopic ultrasound-guided sampling: systematic review and meta-analysis.

    Science.gov (United States)

    Oh, Hyoung-Chul; Kang, Hyun; Lee, Jae Young; Choi, Geun Joo; Choi, Jung Sik

    2016-11-01

    To compare the diagnostic accuracy of endoscopic ultrasound-guided core needle aspiration with that of standard fine-needle aspiration by systematic review and meta-analysis. Studies using 22/25-gauge core needles, irrespective of comparison with standard fine needles, were comprehensively reviewed. Pooled sensitivity, specificity, diagnostic odds ratio (DOR), and summary receiver operating characteristic curves for the diagnosis of malignancy were used to estimate the overall diagnostic efficiency. The pooled sensitivity, specificity, and DOR of the core needle for the diagnosis of malignancy were 0.88 (95% confidence interval [CI], 0.84 to 0.90), 0.99 (95% CI, 0.96 to 1), and 167.37 (95% CI, 65.77 to 425.91), respectively. The pooled sensitivity, specificity, and DOR of the standard needle were 0.84 (95% CI, 0.79 to 0.88), 1 (95% CI, 0.97 to 1), and 130.14 (95% CI, 34.00 to 495.35), respectively. The area under the curve of core and standard needle in the diagnosis of malignancy was 0.974 and 0.955, respectively. The core and standard needle were comparable in terms of pancreatic malignancy diagnosis. There was no significant difference in procurement of optimal histologic cores between core and standard needles (risk ratio [RR], 0.545; 95% CI, 0.187 to 1.589). The number of needle passes for diagnosis was significantly lower with the core needle (standardized mean difference, -0.72; 95% CI, -1.02 to -0.41). There were no significant differences in overall complications (RR, 1.26; 95% CI, 0.34 to 4.62) and technical failure (RR, 5.07; 95% CI, 0.68 to 37.64). Core and standard needles were comparable in terms of diagnostic accuracy, technical performance, and safety profile.

  17. Test plan for core sampling drill bit temperature monitor

    International Nuclear Information System (INIS)

    Francis, P.M.

    1994-01-01

    At WHC, one of the functions of the Tank Waste Remediation System division is sampling waste tanks to characterize their contents. The push-mode core sampling truck is currently used to take samples of liquid and sludge. Sampling of tanks containing hard salt cake is to be performed with the rotary-mode core sampling system, consisting of the core sample truck, mobile exhauster unit, and ancillary subsystems. When drilling through the salt cake material, friction and heat can be generated in the drill bit. Based upon tank safety reviews, it has been determined that the drill bit temperature must not exceed 180 C, due to the potential reactivity of tank contents at this temperature. Consequently, a drill bit temperature limit of 150 C was established for operation of the core sample truck to have an adequate margin of safety. Unpredictable factors, such as localized heating, cause this buffer to be so great. The most desirable safeguard against exceeding this threshold is bit temperature monitoring . This document describes the recommended plan for testing the prototype of a drill bit temperature monitor developed for core sampling by Sandia National Labs. The device will be tested at their facilities. This test plan documents the tests that Westinghouse Hanford Company considers necessary for effective testing of the system

  18. Operational report, Formation of the XXVII reactor core, plan of fuel exchange

    International Nuclear Information System (INIS)

    Martinc, R.

    1977-01-01

    Plan for fuel exchange for formation of the reactor core No. XXVII is presented. This report includes: the quantity of 80% enriched fuel which is input in the core, description of the fuel 'transfer' through the core within this fuelling scheme. It covers the review of reactor safety operating with the core No. XXVII related to reactivity change, thermal load of the fuel channels and fuel burnup. These data result from the analysis based on the same correlated calculation method which was applied for planning the first regular fuel exchange with 80% enriched fuel (core No. XXVI configuration), which has been approved in february 1977. Based on the enclosed data and the fuel exchange according to the proposed procedure it is expected that the reactor operation with core No. XXVII configuration will be safe [sr

  19. Core science and technology development plan for indirect-drive ICF ignition. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    Powell, H.T.; Kilkenny, J.D. [eds.

    1995-12-01

    To define the development work needed to support inertial confinement fusion (ICF) program goals, the authors have assembled this Core Science and Technology (CS and T) Plan that encompasses nearly all science research and technology development in the ICF program. The objective of the CS and T Plan described here is to identify the development work needed to ensure the success of advanced ICF facilities, in particular the National Ignition Facility (NIF). This plan is intended as a framework to facilitate planning and coordination of future ICF programmatic activities. The CS and T Plan covers all elements of the ICF program including laser technology, optic manufacturing, target chamber, target diagnostics, target design and theory, target components and fabrication, and target physics experiments. The CS and T Plan has been divided into these seven different technology development areas, and they are used as level-1 categories in a work breakdown structure (WBS) to facilitate the organization of all activities in this plan. The scope of the CS and T Plan includes all research and development required to support the NIF leading up to the activation and initial operation as an indirect-drive facility. In each of the CS and T main development areas, the authors describe the technology and issues that need to be addressed to achieve NIF performance goals. To resolve all issues and achieve objectives, an extensive assortment of tasks must be performed in a coordinated and timely manner. The authors describe these activities and present planning schedules that detail the flow of work to be performed over a 10-year period corresponding to estimated time needed to demonstrate fusion ignition with the NIF. Besides the benefits to the ICF program, the authors also discuss how the commercial sector and the nuclear weapons science may profit from the proposed research and development program.

  20. Core science and technology development plan for indirect-drive ICF ignition. Revision 1

    International Nuclear Information System (INIS)

    Powell, H.T.; Kilkenny, J.D.

    1995-12-01

    To define the development work needed to support inertial confinement fusion (ICF) program goals, the authors have assembled this Core Science and Technology (CS and T) Plan that encompasses nearly all science research and technology development in the ICF program. The objective of the CS and T Plan described here is to identify the development work needed to ensure the success of advanced ICF facilities, in particular the National Ignition Facility (NIF). This plan is intended as a framework to facilitate planning and coordination of future ICF programmatic activities. The CS and T Plan covers all elements of the ICF program including laser technology, optic manufacturing, target chamber, target diagnostics, target design and theory, target components and fabrication, and target physics experiments. The CS and T Plan has been divided into these seven different technology development areas, and they are used as level-1 categories in a work breakdown structure (WBS) to facilitate the organization of all activities in this plan. The scope of the CS and T Plan includes all research and development required to support the NIF leading up to the activation and initial operation as an indirect-drive facility. In each of the CS and T main development areas, the authors describe the technology and issues that need to be addressed to achieve NIF performance goals. To resolve all issues and achieve objectives, an extensive assortment of tasks must be performed in a coordinated and timely manner. The authors describe these activities and present planning schedules that detail the flow of work to be performed over a 10-year period corresponding to estimated time needed to demonstrate fusion ignition with the NIF. Besides the benefits to the ICF program, the authors also discuss how the commercial sector and the nuclear weapons science may profit from the proposed research and development program

  1. Diagnostics Plan for the National Compact Stellarator Experiment

    International Nuclear Information System (INIS)

    D. Johnson; T. Brown; H. Neilson; G. Schilling; H. Takahashi; M. Zarnstorff; M. Cole; E. Lazarus; and M. Fenstermacher

    2002-01-01

    The National Compact Stellarator Experiment (NCSX) is a stellarator-tokamak hybrid seeking to combine the good confinement, high beta and moderate aspect ratio of the tokamak with the quasi-steady-state operation and good stability properties of the stellarator. A preliminary list of measurement requirements, intended to satisfy the needs of the phased research plan, provides the basis for a full complement of plasma diagnostics. It is important to consider this full set, even at this early stage, to assess the adequacy of the stellarator design for diagnostic port access. The 3-D nature of the plasma is a measurement challenge, as is the necessity for high spatial resolution to assess the quality of magnetic surfaces. Other diagnostic requirements include the need for re-entrant views that penetrate the cryostat, for a convenient e-beam probe for field line mapping, and for a diagnostic neutral beam for active spectroscopy

  2. Meta-Review of CSF core biomarkers in Alzheimer’s disease: the state-of-the-art after the new revised diagnostic criteria

    Directory of Open Access Journals (Sweden)

    Daniel eFerreira

    2014-03-01

    Full Text Available Background: Current research criteria for Alzheimer’s disease (AD include Cerebrospinal Fluid (CSF biomarkers into the diagnostic algorithm. However, spreading their use to the clinical routine is still questionable. Objective: To provide an updated, systematic and critical review on the diagnostic utility of the CSF core biomarkers for AD. Data sources: MEDLINE, PreMedline, EMBASE, PsycInfo, CINAHL, Cochrane Library, and CRD.Eligibility criteria: 1a Systematic reviews with meta-analysis; 1b Primary studies published after the new revised diagnostic criteria; 2 Evaluation of the diagnostic performance of at least one CSF core biomarker.Results: The diagnostic performance of CSF biomarkers is generally satisfactory. They are optimal for discriminating AD patients from healthy controls. Their combination may also be suitable for Mild Cognitive Impairment (MCI prognosis. However, CSF biomarkers fail to distinguish AD from other forms of dementia. Limitations: 1 use of clinical diagnosis as standard instead of pathological postmortem confirmation; 2 variability of methodological aspects; 3 insufficiently long follow-up periods in MCI studies; and 4 lower diagnostic accuracy in primary care compared with memory clinics. Conclusions: Additional work needs to be done to validate the application of CSF core biomarkers as they are proposed in the new revised diagnostic criteria. The use of CSF core biomarkers in clinical routine is more likely if these limitations are overcome. Early diagnosis is going to be of utmost importance when effective pharmacological treatment will be available and the CSF core biomarkers can also be implemented in clinical trials for drug development.

  3. Meta-Review of CSF Core Biomarkers in Alzheimer’s Disease: The State-of-the-Art after the New Revised Diagnostic Criteria

    Science.gov (United States)

    Ferreira, Daniel; Perestelo-Pérez, Lilisbeth; Westman, Eric; Wahlund, Lars-Olof; Sarría, Antonio; Serrano-Aguilar, Pedro

    2014-01-01

    Background: Current research criteria for Alzheimer’s disease (AD) include cerebrospinal fluid (CSF) biomarkers into the diagnostic algorithm. However, spreading their use to the clinical routine is still questionable. Objective: To provide an updated, systematic and critical review on the diagnostic utility of the CSF core biomarkers for AD. Data sources: MEDLINE, PreMedline, EMBASE, PsycInfo, CINAHL, Cochrane Library, and CRD. Eligibility criteria: (1a) Systematic reviews with meta-analysis; (1b) Primary studies published after the new revised diagnostic criteria; (2) Evaluation of the diagnostic performance of at least one CSF core biomarker. Results: The diagnostic performance of CSF biomarkers is generally satisfactory. They are optimal for discriminating AD patients from healthy controls. Their combination may also be suitable for mild cognitive impairment (MCI) prognosis. However, CSF biomarkers fail to distinguish AD from other forms of dementia. Limitations: (1) Use of clinical diagnosis as standard instead of pathological postmortem confirmation; (2) variability of methodological aspects; (3) insufficiently long follow-up periods in MCI studies; and (4) lower diagnostic accuracy in primary care compared with memory clinics. Conclusion: Additional work needs to be done to validate the application of CSF core biomarkers as they are proposed in the new revised diagnostic criteria. The use of CSF core biomarkers in clinical routine is more likely if these limitations are overcome. Early diagnosis is going to be of utmost importance when effective pharmacological treatment will be available and the CSF core biomarkers can also be implemented in clinical trials for drug development. PMID:24715863

  4. Program plan for shipment, receipt, and storage of the TMI-2 core. Revision 1

    International Nuclear Information System (INIS)

    Quinn, G.J.; Reno, H.W.; Schmitt, R.C.

    1985-01-01

    This plan addresses the preparation and shipment of core debris from Three Mile Island Unit 2 (TMI-2) to the Idaho National Engineering Laboratory (INEL) and receipt and storage of that core debris. The Manager of the Nuclear Materials Evaluation Programs Division of EG and G Idaho, Inc. will manage two separate but integrated programs, one located at TMI (Part 1) and the other at INEL (Part 2). The Technical Integration Office (at TMI) is responsible for developing and implementing Part 1, TMI-2 Core Shipment Program. The Technical Support Branch (at INEL) is responsible for developing and implementing Part 2, TMI-2 Core Receipt and Storage. The plan described herein is a revision of a previous document entitled Plan for Shipment, Storage, and Examination of TMI-2 Fuel. This revision was required to delineate changes, primarily in Part 2, Core Activities Program, of the previous document. That part of the earlier document related to core examination was reidentified in mid-FY-1984 as a separate trackable entity entitled Core Sample Acquisition and Examination Project, which is not included here

  5. Status of the R&D activities to the design of an ITER core CXRS diagnostic system

    Energy Technology Data Exchange (ETDEWEB)

    Mertens, Philippe, E-mail: ph.mertens@fz-juelich.de [Institute of Energy and Climate Research IEK-4 (Plasma Physics), Forschungszentrum Jülich (FZJ), Trilateral Euregio Cluster, D-52425 Jülich (Germany); Castaño Bardawil, David A. [Institute of Energy and Climate Research IEK-4 (Plasma Physics), Forschungszentrum Jülich (FZJ), Trilateral Euregio Cluster, D-52425 Jülich (Germany); Baross, Tétény [Wigner Research Centre for Physics (Wigner RCP), HU-1121 Budapest (Hungary); Biel, Wolfgang; Friese, Sebastian [Institute of Energy and Climate Research IEK-4 (Plasma Physics), Forschungszentrum Jülich (FZJ), Trilateral Euregio Cluster, D-52425 Jülich (Germany); Hawkes, Nick [Culham Centre for Fusion Energy (CCFE), Culham OX14 3DB (United Kingdom); Jaspers, Roger J.E. [Eindhoven University of Technology (TU/e), PO Box 513, NL-5600 MB Eindhoven (Netherlands); Kotov, Vladislav; Krasikov, Yury; Krimmer, Andreas; Litnovsky, Andrey; Marchuk, Oleksander; Neubauer, Olaf [Institute of Energy and Climate Research IEK-4 (Plasma Physics), Forschungszentrum Jülich (FZJ), Trilateral Euregio Cluster, D-52425 Jülich (Germany); Offermanns, Guido [Zentralinstitut für Engineering, Elektronik und Analytik ZEA-1 (Engineering and Technology), FZJ, Trilateral Euregio Cluster, D-52425 Jülich (Germany); Panin, Anatoly [Institute of Energy and Climate Research IEK-4 (Plasma Physics), Forschungszentrum Jülich (FZJ), Trilateral Euregio Cluster, D-52425 Jülich (Germany); and others

    2015-10-15

    Highlights: • The CXRS diagnostic for the core plasma of ITER will provide observation of the dedicated diagnostic beam (DNB) over a wide radial range, roughly r/a = 0.7 to 0. • A high performance (étendue × transmission, dynamic range) is expected for the port plug system since the beam attenuation is large and the background light omnipresent. • The design is particularly challenging in view of the ITER environment, especially with respect to the first mirror which faces the plasma. • The current status of development is presented by detailing several sub-systems before a four years design phase under an FPA between F4E and the ITER core CXRS Consortium (IC3). - Abstract: The CXRS (Charge-eXchange Recombination Spectroscopy) diagnostic for the core plasma of ITER will be designed to provide observation of the dedicated diagnostic beam (DNB) over a wide radial range, roughly from a normalised radius r/a = 0.7 to close to the plasma axis. The collected light will be transported through the Upper Port Plug #3 (UPP3) to a bundle of fibres and ultimately to a set of remote spectrometers. The design is particularly challenging in view of the ITER environment of particle, heat and neutron fluxes, temperature cycles, electromagnetic loads, vibrations, expected material degradation and fatigue, constraints against tritium penetration, integration in the plug and limited opportunities for maintenance. Moreover, a high performance (étendue × transmission, dynamic range) is expected for the port plug system since the beam attenuation is large and the background light omnipresent, especially in terms of bremsstrahlung, line radiation and reflections. The present contribution will give an overview of the current status and activities which deal with the core CXRS system, summarising the investigations which have taken place before entering the actual development and design phase.

  6. Tank 241-BY-105 rotary core sampling and analysis plan

    International Nuclear Information System (INIS)

    Sasaki, L.M.

    1995-01-01

    This Sampling and Analysis Plan (SAP) identifies characterization objectives pertaining to sample collection, laboratory analytical evaluation, and reporting requirements for two rotary-mode core samples from tank 241-BY-105 (BY-105)

  7. Ultrasound-guided diagnostic breast biopsy methodology: retrospective comparison of the 8-gauge vacuum-assisted biopsy approach versus the spring-loaded 14-gauge core biopsy approach

    Science.gov (United States)

    2011-01-01

    Background Ultrasound-guided diagnostic breast biopsy technology represents the current standard of care for the evaluation of indeterminate and suspicious lesions seen on diagnostic breast ultrasound. Yet, there remains much debate as to which particular method of ultrasound-guided diagnostic breast biopsy provides the most accurate and optimal diagnostic information. The aim of the current study was to compare and contrast the 8-gauge vacuum-assisted biopsy approach and the spring-loaded 14-gauge core biopsy approach. Methods A retrospective analysis was done of all ultrasound-guided diagnostic breast biopsy procedures performed by either the 8-gauge vacuum-assisted biopsy approach or the spring-loaded 14-gauge core biopsy approach by a single surgeon from July 2001 through June 2009. Results Among 1443 ultrasound-guided diagnostic breast biopsy procedures performed, 724 (50.2%) were by the 8-gauge vacuum-assisted biopsy technique and 719 (49.8%) were by the spring-loaded 14-gauge core biopsy technique. The total number of false negative cases (i.e., benign findings instead of invasive breast carcinoma) was significantly greater (P = 0.008) in the spring-loaded 14-gauge core biopsy group (8/681, 1.2%) as compared to in the 8-gauge vacuum-assisted biopsy group (0/652, 0%), with an overall false negative rate of 2.1% (8/386) for the spring-loaded 14-gauge core biopsy group as compared to 0% (0/148) for the 8-gauge vacuum-assisted biopsy group. Significantly more (P guided diagnostic breast biopsy procedure. Significantly more (P guided diagnostic breast biopsy procedure. Conclusions In appropriately selected cases, the 8-gauge vacuum-assisted biopsy approach appears to be advantageous to the spring-loaded 14-gauge core biopsy approach for providing the most accurate and optimal diagnostic information. PMID:21835024

  8. Thematic plan on diagnostic radiology

    International Nuclear Information System (INIS)

    2003-01-01

    Due to the vital importance of diagnostic radiology in both the diagnosis and management of disease processes, there is a need for a greater coherent international effort to help the developing nations create strategies for the incorporation of imaging into their healthcare systems. To meet the needs of such countries, a comprehensive programme is required to take into consideration the availability of local expertise (medical and technical), the infrastructure (stable electrical supply, water and air-conditioning) and the disease pattern or burden. In short, the total solution requires coordinating the International Atomic Energy Agency efforts with those of other partners. The Agency already has programmes in nuclear medicine and radiation therapy supported by activities in dosimetry and medical physics. Through the Technical Co-operation fund the Agency already supports projects in some areas of diagnostic imaging, dosimetry and radiation protection, but it lacks a comprehensive programme to provide a systematic approach focusing on the medical aspects of imaging science and including all the imaging technologies. Member States require the Agency's assistance in this area since no single UN organisation has the resources or the expertise to do the entire job without help. This document presents the proposed programme strategy and action plan

  9. The Effects of Signal Erosion and Core Genome Reduction on the Identification of Diagnostic Markers

    Directory of Open Access Journals (Sweden)

    Jason W. Sahl

    2016-09-01

    Full Text Available Whole-genome sequence (WGS data are commonly used to design diagnostic targets for the identification of bacterial pathogens. To do this effectively, genomics databases must be comprehensive to identify the strict core genome that is specific to the target pathogen. As additional genomes are analyzed, the core genome size is reduced and there is erosion of the target-specific regions due to commonality with related species, potentially resulting in the identification of false positives and/or false negatives.

  10. Aligning Funding and Need for Family Planning: A Diagnostic Methodology

    Science.gov (United States)

    Fan, Victoria Y.; Kim, Sunja; Choi, Seemoon; Grépin, Karen A.

    2017-01-01

    Abstract With limited international resources for family planning, donors must decide how to allocate their funds to different countries. How can a donor for family planning decide whether countries are adequately prioritized for funding? This article proposes an ordinal ranking framework to identify under‐prioritized countries by rank‐ordering countries by their need for family planning and separately rank‐ordering them by their development assistance for family planning. Countries for which the rank of the need for family planning is lower than the rank of its funding are deemed under‐prioritized. We implement this diagnostic methodology to identify under‐prioritized countries that have a higher need but lower development assistance for family planning. This approach indicates whether a country is receiving less compared to other countries with similar levels of need. PMID:29044592

  11. observer-based diagnostics and monitoring of vibrations in nuclear reactor core cooling system

    International Nuclear Information System (INIS)

    Siry, S.A K.

    2007-01-01

    analysis and diagnostics of vibration in industrial systems play a significant rule to prevent severe severe damages . drive shaft vibration is a complicated phenomenon composed of two independent forms of vibrations, translational and torsional. translational vibration measurements in case of the reactor core cooling system are introduced. the system under study consists of the three phase induction motor, flywheel, centrifugal pump, and two coupling between motor-flywheel, and flywheel-pump. this system structure is considered to be one where the blades are pegged into the discs fitting into the shafts. a non-linear model to simulate vibration in the reactor core cooling system will be introduced. simulation results of an operating reactor core cooling system using the actual parameters will be presented to validate the accuracy and reliability of the proposed analytical method the accuracy in analyzing the results depends on the system model. the shortcomings of the conventional model will be avoided through the use of that accurate nonlinear model which improve the simulation of the reactor core cooling system

  12. Some developments in core-barrel vibration diagnostics

    International Nuclear Information System (INIS)

    Pazsit, I.; Karlsson, J.; Garis, N.S.

    1998-01-01

    Diagnostics of core-barrel motion, and notably that of beam mode vibrations, has been usually performed by two distinct concepts. One strategy is to perform a qualitative analysis in the time domain, using descriptors such as vibration trajectory, probability distributions etc. This approach is rather realistic in the sense that it allows for general anisotropic pendular vibrations. The other strategy is to use frequency analysis with the goal of quantifying certain vibration properties. However, this second approach could so far handle only isotropic and unidirectional vibrations. In this paper we propose a unification of these two approaches by introducing a model by which general anisotropic vibrations can be quantified in the frequency domain. However, when separating the noise components prior to the frequency analysis, we suggest the use of symmetry properties of the noise in the time domain, based on reactor physics assumptions, as opposed to the earlier methods that use statistical independence of the components. Due to the unified approach, a combination of time and frequency domain analysis methods can be used for presentation and maximum information extraction

  13. Calibration of the charge exchange recombination spectroscopy diagnostic for core poloidal rotation velocity measurements on JET

    International Nuclear Information System (INIS)

    Crombe, K.; Andrew, Y.; Giroud, C.; Hawkes, N.C.; Murari, A.; Valisa, M.; Oost, G. van; Zastrow, K.-D.

    2004-01-01

    This article describes recent improvements in the measurement of C 6+ impurity ion poloidal rotation velocities in the core plasma of JET using charge exchange recombination spectroscopy. Two independent techniques are used to provide an accurate line calibration. The first method uses a Perkin-Elmer type 303-306 samarium hollow cathode discharge lamp, with a Sm I line at 528.291 nm close to the C VI line at 529.1 nm. The second method uses the Be II at 527.06 nm and C III at 530.47 nm in the plasma spectrum as two marker lines on either side of the C VI line. Since the viewing chords have both a toroidal and poloidal component, it is important to determine the contribution of the toroidal rotation velocity component separately. The toroidal rotation velocity in the plasma core is measured with an independent charge exchange recombination spectroscopy diagnostic, looking tangentially at the plasma core. The contribution of this velocity along the lines of sight of the poloidal rotation diagnostic has been determined experimentally in L-mode plasmas keeping the poloidal component constant (K. Crombe et al., Proc. 30th EPS Conference, St. Petersburg, Russia, 7-11 July 2003, p. 1.55). The results from these experiments are compared with calculations of the toroidal contribution that take into account the original design parameters of the diagnostic and magnetic geometry of individual shots

  14. Proceeding of JSPS-CAS Core University Program seminar on production and control of high performance plasmas with advanced plasma heating and diagnostic systems

    International Nuclear Information System (INIS)

    Gao Xiang; Morita, Shigeru

    2011-02-01

    The JSPS-CAS Core University Program (CUP) seminar on 'Production and control of high performance plasmas with advanced plasma heating and diagnostic systems' took place in Guilin Bravo Hotel, Guilin, China, 1-4 November 2010. This seminar was organized in the framework of CUP in the field of plasma and nuclear fusion. Two special talks and 46 oral talks were presented in the seminar including 36 Chinese, 18 Japanese and 4 Korean attendees. Production and control of high performance plasmas is a crucial issue for realizing an advanced nuclear fusion reactor in addition to developments of advanced plasma heating and diagnostics. This seminar was motivated along the issues. Results in the field of fusion experiments obtained through CUP activities during recent two years were summarized. Possible direction of future collaboration and further encouragement of scientific activity of younger scientists were also discussed in this seminar with future experimental plans in both countries. (author)

  15. Strategic planning for radiology: opening an outpatient diagnostic imaging center.

    Science.gov (United States)

    Leepson, Evan

    2003-01-01

    Launching a new diagnostic imaging center involves very specific requirements and roadmaps, including five major areas of change that have a direct impact on planning: Imaging and communication technology Finances and reimbursement Ownership structure of imaging entities Critical workforce shortages Imaging is moving outside radiology First, planning must focus on the strategic level of any organization, whether it is a multi-national corporation or a six-person radiology group. Think of all organizations as a triangle with three horizontal levels: strategic, managerial and operational. The strategic level of decision-making is at the top of the triangle, and here is where planning must take place. For strategic planning to work, there must be focused time and energy spent on this activity, usually away from the reading room and imaging center. There are five planning strategies, which must have the explicit goal of developing and growing the imaging center. The five strategies are: Clinical and quality issues, Governance and administration, Technology, Relationships, Marketing and business development. The best way to plan and implement these strategies is to create work groups of radiologists, technologists, and administrative and support staff. Once the group agrees on the strategy and tactic, it takes responsibility for implementation. Embarking on the launch of a new outpatient diagnostic imaging center is no small undertaking, and anyone who has struggled with such an endeavor can readily attest to the associated challenges and benefits. Success depends on many things, and one of the most important factors relates to the amount of time and the quality of effort spent on strategic planning at the outset. Neglecting or skimping on this phase may lead to unforeseen obstacles that could potentially derail the project.

  16. What is the added value of combined core biopsy and fine needle aspiration in the diagnostic process of renal tumours?

    NARCIS (Netherlands)

    Barwari, K.; Kümmerlin, I.P.E.D.; Ten Kate, F.J.; Algaba, F.; Trias, I.; Wijkstra, H.; Rosette, de la J.J.M.C.H.; Laguna, M.P.

    2013-01-01

    Purpose Non-diagnostic results still hinder the routine use of core biopsy (CB) and fine needle aspiration (FNA) in the diagnostic process of renal tumours. Furthermore, substantial interobserver variability has been reported. We assessed the added value of combining the results of CB and FNA by

  17. What is the added value of combined core biopsy and fine needle aspiration in the diagnostic process of renal tumours?

    NARCIS (Netherlands)

    Barwari, K.; Kummerlin, I. P.; ten Kate, F. J.; Algaba, F.; Trias, I.; Wijkstra, H.; de la Rosette, J. J.; Laguna, P.

    2013-01-01

    Non-diagnostic results still hinder the routine use of core biopsy (CB) and fine needle aspiration (FNA) in the diagnostic process of renal tumours. Furthermore, substantial interobserver variability has been reported. We assessed the added value of combining the results of CB and FNA by five

  18. International solar-terrestrial physics program: a plan for the core spaceflight missions

    Energy Technology Data Exchange (ETDEWEB)

    1985-01-01

    This brochure has been prepared to describe the scope of the science problems to be investigated and the mission plan for the core International Solar-Terrestrial Physics (ISTP) Program. This information is intended to stimulate discussions and plans for the comprehensive worldwide ISTP Program. The plan for the study of the solar - terrestrial system is included. The Sun, geospace, and Sun-Earth interaction is discussed as is solar dynamics and the origins of solar winds.

  19. Tank 241-U-105 push mode core sampling and analysis plan

    International Nuclear Information System (INIS)

    Bell, K.E.

    1995-01-01

    This Sampling and Analysis Plan (SAP) will identify characterization objectives pertaining to sample collection, laboratory analytical evaluation, and reporting requirements for vapor samples and two push mode core samples from tank 241-U-105 (U-105)

  20. Factors influencing diagnostic yield of CT-guided percutaneous core needle biopsy for bone lesions

    International Nuclear Information System (INIS)

    Li, Y.; Du, Y.; Luo, T.Y.; Yang, H.F.; Yu, J.H.; Xu, X.X.; Zheng, H.J.; Li, B.

    2014-01-01

    Aim: To evaluate the factors influencing diagnostic yield of computed tomography (CT)-guided percutaneous core needle biopsy (CNB) for bone lesions. Materials and methods: Between September 2005 and July 2011, 162 consecutive CT-guided CNB procedures were performed in 155 patients. The variables analysed were age, sex, lesion location, lesion type, lesion size, specimen size, biopsy needle gauge, and individual radiologist. The factors influencing diagnostic yield of CT-guided percutaneous CNB for bone lesions were determined by multivariate analysis of variables. Results: The diagnostic yield was 81.5%. Diagnostic yield was 89.9% for lytic bone lesions and 48.5% for sclerotic bone lesions (p < 0.001), and 89.2% for lesions ≥3 cm and 73.4% for lesions <3 cm (p = 0.010). The significant factors influencing diagnostic yield of CT-guided percutaneous CNB for bone lesions were lesion type [p < 0.001; odds ratio (OR) for a lytic lesion was approximately 12 times higher than that for a sclerotic lesion; 95% confidence interval (CI): 4.22–34.01], and lesion size (p = 0.012; OR for a lesion size ≥3 cm was about five-times higher than that for a lesion size <3 cm; 95% CI: 1.42–16.71). Conclusion: Lesion type and lesion size are determining factors in diagnostic yield. The higher diagnostic yield is correlated with lytic lesion and lesion size ≥3 cm

  1. Computed-Tomography-Guided Percutaneous Core Needle Biopsies of Suspected Malignant Lymphomas: Impact of Biopsy, Lesion, and Patient Parameters on Diagnostic Yield

    International Nuclear Information System (INIS)

    Hesselmann, V.; Zaehringer, M.; Krug, B.; Wesselmann, C.; Haferkamp, K.; Wickenhauser, C.; Lackner, K.

    2004-01-01

    Purpose: To investigate the diagnostic yield of core needle biopsy in patients with malignant lymphoma. Material and Methods: Computed-tomography-guided core needle biopsies in patients with malignant lymphoma performed in the period 1996 to 2001 were evaluated retrospectively. A biopsy was considered as 'fully diagnostic' if a histological diagnosis, including the histologic subtype in the event of malignant lymphoma, was achieved and the clinical course and CT follow-up of at least 6 months confirmed the biopsy results. A biopsy was regarded as 'partly diagnostic' if histological work-up defined malignant lymphoma but not the histological subtype, and if histological diagnosis bore therapeutic relevance. Diagnostic yield was correlated with features such as size of specimen, location and depth of the target lesion, and experience of the investigator. Results: 45 biopsies were performed in 40 patients. With respect to definite histopathological diagnosis, 31 biopsies (68.9%) were diagnostic and 14 (31.1%) non-diagnostic. In 4 cases (8.8%), biopsies yielded partly diagnostic results, since therapy could be scheduled after biopsy without final sub-classification. Statistical analysis of biopsy parameters revealed that sample sizes were significantly larger in the diagnostic group. Conclusion: CT-guided biopsy can be considered as an alternative for lymphoma diagnosis and should be the first interventional procedure. The most important parameter for diagnostic success is the size of the specimen

  2. Engineering Task Plan to Expand the Environmental Operational Envelope of Core Sampling

    International Nuclear Information System (INIS)

    BOGER, R.M.

    1999-01-01

    This Engineering Task Plan authorizes the development of an Alternative Generation and Analysis (AGA). The AGA will determine how to expand the environmental operating envelope during core sampling operations

  3. Approaches to Demonstrating the Reliability and Validity of Core Diagnostic Criteria for Chronic Pain.

    Science.gov (United States)

    Bruehl, Stephen; Ohrbach, Richard; Sharma, Sonia; Widerstrom-Noga, Eva; Dworkin, Robert H; Fillingim, Roger B; Turk, Dennis C

    2016-09-01

    The Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities, and Networks-American Pain Society Pain Taxonomy (AAPT) is designed to be an evidence-based multidimensional chronic pain classification system that will facilitate more comprehensive and consistent chronic pain diagnoses, and thereby enhance research, clinical communication, and ultimately patient care. Core diagnostic criteria (dimension 1) for individual chronic pain conditions included in the initial version of AAPT will be the focus of subsequent empirical research to evaluate and provide evidence for their reliability and validity. Challenges to validating diagnostic criteria in the absence of clear and identifiable pathophysiological mechanisms are described. Based in part on previous experience regarding the development of evidence-based diagnostic criteria for psychiatric disorders, headache, and specific chronic pain conditions (fibromyalgia, complex regional pain syndrome, temporomandibular disorders, pain associated with spinal cord injuries), several potential approaches for documentation of the reliability and validity of the AAPT diagnostic criteria are summarized. The AAPT is designed to be an evidence-based multidimensional chronic pain classification system. Conceptual and methodological issues related to demonstrating the reliability and validity of the proposed AAPT chronic pain diagnostic criteria are discussed. Copyright © 2016 American Pain Society. Published by Elsevier Inc. All rights reserved.

  4. Core competency model for the family planning public health nurse.

    Science.gov (United States)

    Hewitt, Caroline M; Roye, Carol; Gebbie, Kristine M

    2014-01-01

    A core competency model for family planning public health nurses has been developed, using a three stage Delphi Method with an expert panel of 40 family planning senior administrators, community/public health nursing faculty and seasoned family planning public health nurses. The initial survey was developed from the 2011 Title X Family Planning program priorities. The 32-item survey was distributed electronically via SurveyMonkey(®). Panelist attrition was low, and participation robust resulting in the final 28-item model, suggesting that the Delphi Method was a successful technique through which to achieve consensus. Competencies with at least 75% consensus were included in the model and those competencies were primarily related to education/counseling and administration of medications and contraceptives. The competencies identified have implications for education/training, certification and workplace performance. © 2014 Wiley Periodicals, Inc.

  5. The simultaneous measurements of core and outer core density fluctuations in L-H transition using CO2 laser collective scattering diagnostic in the EAST superconducting tokamak

    International Nuclear Information System (INIS)

    Cao, G.M.; Li, Y.D.; Zhang, X.D.; Sun, P.J.; Hu, L.Q.; Li, J.G.; Wu, G.J.

    2013-01-01

    The H-mode is the projected basic operation scenario for the ITER tokamak. The turbulence de-correlation by the synergistic effect of zonal flow and equilibrium ExB flow shear is believed to be the reason for L-H transition, however, the detailed physical mechanism has not been identified so far. Tangential multi-channel CO 2 laser collective scattering diagnostic system (mainly k r measurement) was first installed to investigate electron density fluctuations on EAST tokamak. The measurements in a spontaneous dithering L-H transition show that in core plasma (0 < r/a < 0.5) the low-frequency fluctuations strengthen greatly before L-H transition; meanwhile in outer core plasma (0.2 < r/a < 1) the low-frequency fluctuations strengthen slightly. Bispectral analysis reveals that the coupling strength between low- and high-frequency fluctuations in both core and outer core plasma strengthens greatly before the transition, but the latter is greater than the former. The results indicate that the low-frequency fluctuations of the core and outer core plasma play active, but different, roles in the spontaneous L-H transition. (author)

  6. Preparing diagnostic 3D images for image registration with planning CT images

    International Nuclear Information System (INIS)

    Tracton, Gregg S.; Miller, Elizabeth P.; Rosenman, Julian; Chang, Sha X.; Sailer, Scott; Boxwala, Azaz; Chaney, Edward L.

    1997-01-01

    Purpose: Pre-radiotherapy (pre-RT) tomographic images acquired for diagnostic purposes often contain important tumor and/or normal tissue information which is poorly defined or absent in planning CT images. Our two years of clinical experience has shown that computer-assisted 3D registration of pre-RT images with planning CT images often plays an indispensable role in accurate treatment volume definition. Often the only available format of the diagnostic images is film from which the original 3D digital data must be reconstructed. In addition, any digital data, whether reconstructed or not, must be put into a form suitable for incorporation into the treatment planning system. The purpose of this investigation was to identify all problems that must be overcome before this data is suitable for clinical use. Materials and Methods: In the past two years we have 3D-reconstructed 300 diagnostic images from film and digital sources. As a problem was discovered we built a software tool to correct it. In time we collected a large set of such tools and found that they must be applied in a specific order to achieve the correct reconstruction. Finally, a toolkit (ediScan) was built that made all these tools available in the proper manner via a pleasant yet efficient mouse-based user interface. Results: Problems we discovered included different magnifications, shifted display centers, non-parallel image planes, image planes not perpendicular to the long axis of the table-top (shearing), irregularly spaced scans, non contiguous scan volumes, multiple slices per film, different orientations for slice axes (e.g. left-right reversal), slices printed at window settings corresponding to tissues of interest for diagnostic purposes, and printing artifacts. We have learned that the specific steps to correct these problems, in order of application, are: Also, we found that fast feedback and large image capacity (at least 2000 x 2000 12-bit pixels) are essential for practical application

  7. TMI-2 core examination plan

    International Nuclear Information System (INIS)

    Owen, D.E.; MacDonald, P.E.; Hobbins, R.R.; Ploggr, S.A.

    1982-01-01

    The Three Mile Island (TMI-2) core examination is divided into four stages: (1) before removing the head; (2) before removing the plenum; (3) during defueling; and (4) offsite examinations. Core examinations recommended during the first three stages are primarily devoted to documenting the post-accident condition of the core. The detailed analysis of core damage structures will be performed during offsite examinations at government and commercial hot cell facilities. The primary objectives of these examinations are to enhance the understanding of the degraded core accident sequence, to develop the technical bases for reactor regulations, and to improve LWR design and operation

  8. Tank 241-AZ-102 Privatization Push Mode Core Sampling and Analysis Plan; FINAL

    International Nuclear Information System (INIS)

    TEMPLETON, A.M.

    1999-01-01

    This sampling and analysis plan (SAP) identifies characterization objectives pertaining to sample collection, laboratory analytical evaluation, and reporting requirements for samples obtained from tank 241-AZ-102. The purpose of this sampling event is to obtain information about the characteristics of the contents of 241-AZ-102. Push mode core samples will be obtained from risers 15C and 24A to provide sufficient material for the chemical analyses and tests required to satisfy these data quality objectives. The 222-S Laboratory will extrude core samples, composite the liquids and solids, perform chemical analyses, and provide subsamples to the Process Chemistry Laboratory. The Process Chemistry Laboratory will prepare test plans and perform process tests to evaluate the behavior of the 241-AZ-102 waste undergoing the retrieval and treatment scenarios defined in the applicable DQOs. Requirements for analyses of samples originating in the process tests will be documented in the corresponding test plan

  9. Tank 241-B-203 push mode core sampling and analysis plan. Revision 1

    International Nuclear Information System (INIS)

    Jo, J.

    1995-01-01

    This Sampling and Analysis Plan (SAP) identifies characterization objectives pertaining to sample collection, laboratory analytical evaluation, and reporting requirements for two push-mode core samples from tank 241-B-203 (B-203)

  10. Tank 241-B-204 push mode core sampling and analysis plan. Revision 1

    International Nuclear Information System (INIS)

    Sasaki, L.M.

    1995-01-01

    This Sampling and Analysis Plan (SAP) identifies characterization objectives pertaining to sample collection, laboratory analytical evaluation, and reporting requirements for two push-mode core samples from tank 241-B-204 (B-204)

  11. Engineering task plan for the development, fabrication and installation of rotary mode core sample truck bellows

    International Nuclear Information System (INIS)

    BOGER, R.M.

    1999-01-01

    The Rotary Mode Core Sampling Trucks (RMSCTs) currently use a multi-sectioned bellows between the grapple box and the quill rod to compensate for drill head motion and to provide a path for purge gas. The current bellows, which is detailed on drawing H-2-690059, is expensive to procure, has a lengthy procurement cycle, and is prone to failure. Therefore, a task has been identified to design, fabricate, and install a replacement bellows. This Engineering Task Plan (ETP) is the management plan document for accomplishing the identified tasks. Any changes in scope of the ETP shall require formal direction by the Characterization Engineering manager. This document shall also be considered the work planning document for developmental control per Development Control Requirements (HNF 1999a). This Engineering Task Plan (ETP) is the management plan document for accomplishing the design, fabrication, and installation of a replacement bellows assembly for the Rotary Mode Core Sampling Trucks 3 and 4 (RMCST)

  12. Development plan for an advanced drilling system with real-time diagnostics (Diagnostics-While-Drilling)

    Energy Technology Data Exchange (ETDEWEB)

    FINGER,JOHN T.; MANSURE,ARTHUR J.; PRAIRIE,MICHAEL R.; GLOWKA,D.A.

    2000-02-01

    This proposal provides the rationale for an advanced system called Diagnostics-while-drilling (DWD) and describes its benefits, preliminary configuration, and essential characteristics. The central concept is a closed data circuit in which downhole sensors collect information and send it to the surface via a high-speed data link, where it is combined with surface measurements and processed through drilling advisory software. The driller then uses this information to adjust the drilling process, sending control signals back downhole with real-time knowledge of their effects on performance. The report presents background of related previous work, and defines a Program Plan for US Department of Energy (DOE), university, and industry cooperation.

  13. Utility of core biopsy with concurrent ROSE FNA in the diagnosis of pancreatic tumor-does the biopsy add any diagnostic benefit?

    Science.gov (United States)

    Yan, Lei; Ikemura, Kenji; Park, Ji-Weon

    2018-02-01

    Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) and endoscopic ultrasound-guided core-needle biopsy (EUS-CNB) are widely used for diagnosis of pancreatic tumors. The aim of our study was to compare the diagnostic performance of ROSE EUS-FNA and EUS-CNB for diagnosis of pancreatic malignancy during the same EUS. Patients who underwent both FNA and CNB during the same EUS for pancreatic solid lesion were reviewed retrospectively. Sample adequacy, diagnostic yield (defined as percentage of definitive diagnosis), sensitivity and specificity for malignancy were compared between FNA and CNB. A total of 48 patients with solid pancreatic lesions were evaluated. The proportions of adequate samples were 48/48 (100%) for FNA and 45/48 (93.7%) for core biopsy (P = .24). The diagnostic yield was 42/48 (87.5%) and 33/48 (68.7%) for FNA and CNB respectively (P = .046). The incremental increase in diagnostic yield by combining both methods was 2/48 (4%). The diagnostic yield for malignancy was 30/32 (93.7%) for FNA and 23/32 (71.8%) for CNB (P = .043). The sensitivity for the diagnosis of malignancy for FNA and CNB were 90.6% and 69%, respectively (P = .045). The specificity was 100% for both methods. The sensitivity for diagnosing malignancy increased to 93.8% when the two methods were combined. The difference in diagnostic yield was not associated with lesion size or location. EUS-guided FNA is a superior method of assessing solid pancreatic lesion and pancreatic malignancy with better diagnostic yield and higher sensitivity than EUS-CNB. © 2017 Wiley Periodicals, Inc.

  14. CT-guided core needle biopsy of pleural lesions: Evaluating diagnostic yield and associated complications

    International Nuclear Information System (INIS)

    Niu, Xiang Ke; Bhetuwal, Anup; Yang, Han Feng

    2015-01-01

    The purpose of this study was to retrospectively evaluate the diagnostic accuracy and complications of CT-guided core needle biopsy (CT-guided CNB) of pleural lesion and the possible effects of influencing factors. From September 2007 to June 2013, 88 consecutive patients (60 men and 28 women; mean [+/- standard deviation] age, 51.1 +/- 14.4 years; range, 19-78 years) underwent CT-guided CNB, which was performed by two experienced chest radiologists in our medical center. Out of 88 cases, 56 (63%) were diagnosed as malignant, 28 (31%) as benign and 4 (5%) as indeterminate for CNB of pleural lesions. The final diagnosis was confirmed by either histopathological diagnosis or clinical follow-up. The diagnostic accuracy, sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and complication rates were statistically evaluated. Influencing factors (patient age, sex, lesion size, pleural-puncture angle, patient position, pleural effusion, and number of pleural punctures) were assessed for their effect on accuracy of CT-guided CNB using univariate and subsequent multivariate analysis. Diagnostic accuracy, sensitivity, specificity, PPV, and NPV were 89.2%, 86.1%, 100%, 100%, and 67.8%, respectively. The influencing factors had no significant effect in altering diagnostic accuracy. As far as complications were concerned, occurrence of pneumothorax was observed in 14 (16%) out of 88 patients. Multivariate analysis revealed lesion size/pleural thickening as a significant risk factor (odds ratio [OR]: 8.744, p = 0.005) for occurrence of pneumothorax. Moreover, presence of pleural effusion was noted as a significant protective factor (OR: 0.171, p = 0.037) for pneumothorax. CT-guided CNB of pleural lesion is a safe procedure with high diagnostic yield and low risk of significant complications.

  15. CT-guided core needle biopsy of pleural lesions: Evaluating diagnostic yield and associated complications

    Energy Technology Data Exchange (ETDEWEB)

    Niu, Xiang Ke [Dept. of Radiology, Affiliated Hospital of Chengdu University, Chengdu (China); Bhetuwal, Anup; Yang, Han Feng [Dept. of Radiology, Sichuan Key Laboratory of Medical Imaging, Affiliated Hospital of North Sichuan Medical College, Nanchong (China)

    2015-02-15

    The purpose of this study was to retrospectively evaluate the diagnostic accuracy and complications of CT-guided core needle biopsy (CT-guided CNB) of pleural lesion and the possible effects of influencing factors. From September 2007 to June 2013, 88 consecutive patients (60 men and 28 women; mean [+/- standard deviation] age, 51.1 +/- 14.4 years; range, 19-78 years) underwent CT-guided CNB, which was performed by two experienced chest radiologists in our medical center. Out of 88 cases, 56 (63%) were diagnosed as malignant, 28 (31%) as benign and 4 (5%) as indeterminate for CNB of pleural lesions. The final diagnosis was confirmed by either histopathological diagnosis or clinical follow-up. The diagnostic accuracy, sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and complication rates were statistically evaluated. Influencing factors (patient age, sex, lesion size, pleural-puncture angle, patient position, pleural effusion, and number of pleural punctures) were assessed for their effect on accuracy of CT-guided CNB using univariate and subsequent multivariate analysis. Diagnostic accuracy, sensitivity, specificity, PPV, and NPV were 89.2%, 86.1%, 100%, 100%, and 67.8%, respectively. The influencing factors had no significant effect in altering diagnostic accuracy. As far as complications were concerned, occurrence of pneumothorax was observed in 14 (16%) out of 88 patients. Multivariate analysis revealed lesion size/pleural thickening as a significant risk factor (odds ratio [OR]: 8.744, p = 0.005) for occurrence of pneumothorax. Moreover, presence of pleural effusion was noted as a significant protective factor (OR: 0.171, p = 0.037) for pneumothorax. CT-guided CNB of pleural lesion is a safe procedure with high diagnostic yield and low risk of significant complications.

  16. Application of diagnostic system for diesel engines in nuclear power plant

    International Nuclear Information System (INIS)

    Yoshinaga, Takeshi

    2004-01-01

    The diagnostic system for diesel engines makes a diagnosis of secular change and abnormal indications of diesel engines (DG) by combination of characteristic analysis of engine, lubricating oil, fuel oil, and cooling water. The principles of diagnostic system for DG, results of confirmation of the efficiency and the maintenance plan for DG in the Japan Atomic Power Company are described. DG in the company is classified to a safety device in order to supply the power source to the Emergency Core Cooling System etc., when the power source in the plant is lost, for example, at lightning struck. Characteristics of DG, outline of the diagnostic system for DG, diagnostic technologies such as engine signature analysis, chemical analysis of samples, temperature measurement, degradation mode of DG, and training in the company are stated. (S.Y.)

  17. Diagnostic feasibility and safety of CT-guided core biopsy for lung nodules less than or equal to 8 mm. A single-institution experience

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Ying-Yueh [Taipei Veterans General Hospital, Department of Radiology, Taipei (China); Chen, Chun-Ku [Taipei Veterans General Hospital, Department of Radiology, Taipei (China); National Yang-Ming University, School of Medicine, Taipei (China); National Yang-Ming University, Institute of Clinical Medicine, Taipei (China); Yeh, Yi-Chen [National Yang-Ming University, School of Medicine, Taipei (China); Taipei Veterans General Hospital, Department of Pathology and Laboratory Medicine, Taipei (China); Wu, Mei-Han [Taipei Veterans General Hospital, Department of Radiology, Taipei (China); National Yang-Ming University, School of Medicine, Taipei (China)

    2018-02-15

    This retrospective study evaluated the diagnostic yield and safety of CT-guided core biopsy of pulmonary nodules ≤8 mm. We determined the diagnostic yield and safety profile of CT-guided lung biopsies for 125 pulmonary nodules ≤8 mm. Pathological diagnoses were made by a combination of histopathological examination and imprint cytology. Results were compared with biopsy results for 134 pulmonary nodules >8 and ≤10 mm. Final diagnoses were established in 94 nodules ≤8 mm. The sensitivity, specificity and diagnostic accuracy of CT-guided core biopsy for nodules ≤8 mm were 87.1 % (61/70 nodules), 100 % (24/24) and 90.4 % (85/94), respectively. Diagnostic failure rates were comparable for nodules ≤8 mm and nodules >8 mm and ≤10 mm (9/94, 9.6 % and 7/111, 6.3 %, respectively, P=0.385). The rate of tube thoracostomy for nodules ≤8 mm was comparable to that for nodules >8 and ≤10 mm (1.6 % vs. 0.7 %, P=0.611). Nodules ≤6 mm had a higher non-diagnostic result rate of 15.4 % (6/39) than did nodules >8 and ≤10 mm (3.7 %, 5/134, P=0.017). CT-guided pulmonary biopsy is feasible for lung nodules ≤8 mm, especially those >6 mm, and has an acceptable diagnostic yield and safety profile. (orig.)

  18. SU-F-T-427: Utilization and Evaluation of Diagnostic CT Imaging with MAR Technique for Radiation Therapy Treatment Planning

    International Nuclear Information System (INIS)

    Xu, M; Foster, R; Parks, H; Pankuch, M

    2016-01-01

    Purpose: The objective was to utilize and evaluate diagnostic CT-MAR technique for radiation therapy treatment planning. Methods: A Toshiba-diagnostic-CT acquisition with SEMAR(Single-energy-MAR)-algorism was performed to make the metal-artifact-reduction (MAR) for patient treatment planning. CT-imaging datasets with and without SEMAR were taken on a Catphan-phantom. Two sets of CT-numbers were calibrated with the relative electron densities (RED). A tissue characterization phantom with Gammex various simulating material rods was used to establish the relationship between known REDs and corresponding CT-numbers. A GE-CT-sim acquisition was taken on the Catphan for comparison. A patient with bilateral hip arthroplasty was scanned in the radiotherapy CT-sim and the diagnostic SEMAR-CT on a flat panel. The derived SEMAR images were used as a primary CT dataset to create contours for the target, critical-structures, and for planning. A deformable registration was performed with VelocityAI to track voxel changes between SEMAR and CT-sim images. The SEMAR-CT images with minimal artifacts and high quality of geometrical and spatial integrity were employed for a treatment plan. Treatment-plans were evaluated based on deformable registration of SEMAR-CT and CT-sim dataset with assigned CT-numbers in the metal artifact regions in Eclipse v11 TPS. Results: The RED and CT-number relationships were consistent for the datasets in CT-sim and CT’s with and without SEMAR. SEMAR datasets with high image quality were used for PTV and organ delineation in the treatment planning process. For dose distribution to the PTV through the DVH analysis, the plan using CT-sim with the assigned CT-number showed a good agreement to those on deformable CT-SEMAR. Conclusion: A diagnostic-CT with MAR-algorithm can be utilized for radiotherapy treatment planning with CT-number calibrated to the RED. Treatment planning comparison and DVH shows a good agreement in the PTV and critical organs between

  19. Diagnostic and Hardware Upgrades for the US-PRC PMI Collaboration on EAST

    Science.gov (United States)

    Tritz, Kevin; Maingi, R.; Andruczyk, D.; Canik, J.; Wang, Z.; Wirth, B.; Zinkle, S.; Woller, K.; Hu, J. S.; Luo, G. N.; Gong, X. Z.; EAST Team

    2017-10-01

    Several collaborative diagnostic and hardware upgrades are planned to improve understanding and control of Plasma-Material Interactions on EAST, as part of the US-PRC PMI collaboration. Dual-band thermography adapters, designed by UT-K and ORNL, are being designed for existing IR cameras to improve the accuracy of the divertor heat flux measurements by reducing sensitivity to surface emissivity. These measurements should improve power accounting for EAST discharges, which can show a large gap between input power and divertor exhaust power. MIT is preparing tungsten tiles with fluorine depth markers to measure net erosion of PFC tiles. JHU plans to improve the electronics of the Multi-Energy Soft X-ray diagnostic as well as expand the present edge system to a full core-edge measurement; this will enhance the assessment of the effect of Li injection on tungsten accumulation and transport. In addition to PPPL-developed upgrades to the lithium granule and pellet delivery systems, LANL is assessing core-shell micropellets for pellet ablation analysis. Finally, UIUC and PPPL are developing flowing liquid lithium limiters, both with and without LiMIT tile features, for deployment on EAST. Work supported by DoE award DE-SC0016553.

  20. Thyroid nodules with isolated macrocalcification: Malignancy and diagnostic efficacy of fine-needle aspiration and core needle biopsy

    Energy Technology Data Exchange (ETDEWEB)

    Na, Dong Gyu; Kim, Dae Sik; Kim, Soo Jin [Dept. of Radiology, Human Medical Imaging and Intervention Center, Seoul (Korea, Republic of); Ryoo, Jae Wook [Dept. of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul (Korea, Republic of); Jung, So Lyung [Dept. of Radiology, Seoul St. Mary' s Hospital, College of Medicine, The Catholic University of Korea, Seoul (Korea, Republic of)

    2016-07-15

    This study was performed to determine the malignancy risk of thyroid nodules with isolated macrocalcification and to evaluate the diagnostic efficacy of fine-needle aspiration (FNA) and core needle biopsy (CNB). From May 2008 to December 2014, a total of 44 patients with isolated macrocalcifications were enrolled from 4,081 consecutive patients who underwent FNA or CNB at a single institution. We assessed the malignancy risk of nodules with isolated macrocalcification. We compared the diagnostic results between FNA and CNB, and the diagnostic efficacy of each procedure was evaluated by the rate of inconclusive results. We compared the diagnostic performance for malignancy between FNA and CNB with a criterion of malignant or atypia/follicular lesion of undetermined significance (indeterminate) diagnostic results. We investigated whether the ultrasonographic feature of isolated macrocalcification was predictive of malignancy. The malignancy risk of nodules with isolated macrocalcification was 16.1% in 31 nodules with final diagnoses and 11.4% in all nodules. CNB demonstrated a significantly lower rate of nondiagnostic and inconclusive results than FNA (7.7% vs. 53.8%, P=0.002 and 15.4% vs. 57.7%, P=0.003, respectively) in 26 nodules that underwent both FNA and CNB. CNB showed a marginally higher diagnostic performance for identifying malignancy than FNA (P=0.067). The ultrasonographic features of the anterior margin of isolated macrocalcification were not predictive of malignancy (P>0.999). Thyroid nodules with isolated macrocalcification had a low to intermediate malignancy risk and should not be considered benign nodules. CNB showed a higher diagnostic efficacy than FNA in these nodules.

  1. Thyroid nodules with isolated macrocalcification: Malignancy and diagnostic efficacy of fine-needle aspiration and core needle biopsy

    International Nuclear Information System (INIS)

    Na, Dong Gyu; Kim, Dae Sik; Kim, Soo Jin; Ryoo, Jae Wook; Jung, So Lyung

    2016-01-01

    This study was performed to determine the malignancy risk of thyroid nodules with isolated macrocalcification and to evaluate the diagnostic efficacy of fine-needle aspiration (FNA) and core needle biopsy (CNB). From May 2008 to December 2014, a total of 44 patients with isolated macrocalcifications were enrolled from 4,081 consecutive patients who underwent FNA or CNB at a single institution. We assessed the malignancy risk of nodules with isolated macrocalcification. We compared the diagnostic results between FNA and CNB, and the diagnostic efficacy of each procedure was evaluated by the rate of inconclusive results. We compared the diagnostic performance for malignancy between FNA and CNB with a criterion of malignant or atypia/follicular lesion of undetermined significance (indeterminate) diagnostic results. We investigated whether the ultrasonographic feature of isolated macrocalcification was predictive of malignancy. The malignancy risk of nodules with isolated macrocalcification was 16.1% in 31 nodules with final diagnoses and 11.4% in all nodules. CNB demonstrated a significantly lower rate of nondiagnostic and inconclusive results than FNA (7.7% vs. 53.8%, P=0.002 and 15.4% vs. 57.7%, P=0.003, respectively) in 26 nodules that underwent both FNA and CNB. CNB showed a marginally higher diagnostic performance for identifying malignancy than FNA (P=0.067). The ultrasonographic features of the anterior margin of isolated macrocalcification were not predictive of malignancy (P>0.999). Thyroid nodules with isolated macrocalcification had a low to intermediate malignancy risk and should not be considered benign nodules. CNB showed a higher diagnostic efficacy than FNA in these nodules

  2. TOWARDS DEVELOPING A SUSTAINABLE HERITAGE TOURISM AND CONSERVATION ACTION PLAN FOR IRBID’S HISTORIC CORE

    Directory of Open Access Journals (Sweden)

    Naif Adel Haddad

    2016-11-01

    Full Text Available Tal (mount Irbid in Irbid city, Jordan, with its continuous human occupation from the Bronze Age until the present, demonstrates the main landmark that has guided the spread of the urban growth of the city. The outcome of studies carried out at Irbid’s historic core, in relation to assessing the loss and degradation of the core’s cultural heritage, shall be analyzed, investigated, and discussed, as also concerns, obstacles, and issues of sustainability to this urban heritage conservation and tourism planning. The paper starts by defining the urban heritage for the historic core, which tends to be set aside, in the city’s rapid development. Actually, the remaining historic buildings can also provide the necessary inter-relationships between the historic core areas and the wider urban context to achieve a sustainable and integrated tourism and conservation action plan for the three heritage neighborhoods around the Tal, while building on tourism opportunities and taking into consideration the needs and the vital role of the local community. The paper concludes that urban heritage conservation and protection of the integrity and identity of the historic core city fabric can assist in its branding, promotion, and management in ways that could enhance the local community belonging, quality of everyday lifestyle, and visitors' experience.

  3. Core biopsies of the breast: Diagnostic pitfalls

    Directory of Open Access Journals (Sweden)

    Megha Joshi

    2011-01-01

    Full Text Available The incidence of breast cancer is increasing worldwide. In this review article, the authors compare and contrast the incidence of breast cancer, and the inherent differences in the United States (US and India in screening techniques used for diagnosing breast cancer. In spite of these differences, core biopsies of the breast are common for diagnosis of breast cancer in both countries. The authors describe "Best Practices" in the reporting and processing of core biopsies and in the analysis of estrogen receptor (ER, progesterone receptor (PR, and human epidermal growth factor Receptor 2 (Her2/neu. The pitfalls in the diagnosis of fibroepithelial lesions of the breast on core biopsy are discussed, as also the significance of pseudoangiomatous stromal hyperplasia of the breast (PASH is discussed in core biopsy. In this review, the management and diagnosis of flat epithelial atypia and radiation atypia are elaborated and the use of immunohistochemistry (IHC in papillary lesions, phyllodes tumor, and complex sclerosing lesions (radial scars is illustrated. Rarer lesions such as mucinous and histiocytoid carcinoma are also discussed.

  4. Core-adjacent instrumentation systems for pebble bed reactors for process heat application - state of planning

    International Nuclear Information System (INIS)

    Benninghofen, G.; Serafin, N.; Spillekothen, H.G.; Hecker, R.; Brixy, H.; Serpekian, T.

    1982-06-01

    Planning and theoretical/experimental development work for core surveillance instrumentation systems is being performed to meet requirements of pebble bed reactors for process heat application. Detailed and proved instrumentation concepts are now available for the core-adjacent instrumentation systems. The current work and the results of neutron flux measurements at high temperatures are described. Operation devices for long-term accurate gas outlet temperature measurements up to approximately 1423 deg. K will also be discussed. (author)

  5. Tank 241-TX-113 rotary mode core sampling and analysis plan

    International Nuclear Information System (INIS)

    McCain, D.J.

    1998-01-01

    This sampling and analysis plan (SAP) identities characterization objectives pertaining to sample collection, laboratory analytical evaluation, and reporting requirements for push mode core samples from tank 241-TX-113 (TX-113). The Tank Characterization Technical Sampling Basis document identities Retrieval, Pretreatment and Immobilization as an issue that applies to tank TX-113. As a result, a 150 gram composite of solids shall be made and archived for that program. This tank is not on a Watch List

  6. Thermal and mechanical design of the plasma core CXRS diagnostics for the fusion reactor ITER; Thermische und mechanische Auslegung der Plasma Core CXRS Diagnostik des ITER Kernfusionsreaktors

    Energy Technology Data Exchange (ETDEWEB)

    Greza, H. [WTI Wissenschaftlich-Technische Ingenieurberatung GmbH, Juelich (Germany); Neubauer, O.; Wolters, J. [Forschungszentrum Juelich GmbH (Germany)

    2009-07-01

    In the frame of the research project ITER (international thermonuclear experimental reactor) the plasma state is monitored using the plasma core diagnostics CXRS (charge exchange recombination spectroscopy).The authors describe the thermal and mechanical design of the first mirror of the CXRS diagnostics. The components of the first mirror are exposed to high heat and neutron irradiation. The surface temperature will be 300 to 400 deg C. The misalignment tolerance is plus or minus 0.1 degree. The maximum mechanical stresses in the mirror have to be minimized. The design calculations use the finite element code ANSYS. The results indicate that the heat input from the plasma can be removed by the coolant flow. Further calculation shave to concern the brazed joints between mirror and cooling block.

  7. Thermal and mechanical design of the plasma core CXRS diagnostics for the fusion reactor ITER; Thermische und mechanische Auslegung der Plasma Core CXRS Diagnostik des ITER Kernfusionsreaktors

    Energy Technology Data Exchange (ETDEWEB)

    Greza, H.; Knauff, R. [Wissenschaftlich-Technische Ingenieurberatung GmbH (WTI), Juelich (Germany); Neubauer, O.; Wolters, J.; Offermanns, G.; Biel, W. [Forschungszentrum Juelich GmbH (Germany)

    2011-07-01

    In the frame of the research project ITER (international thermonuclear experimental reactor) the plasma state is monitored using the plasma core diagnostics CXRS (charge exchange recombination spectroscopy).The authors describe the thermal and mechanical design of the first mirror of the CXRS diagnostics. The components of the first mirror are exposed to high heat and neutron irradiation. The surface temperature will be 300 to 400 deg C. The misalignment tolerance is plus or minus 0.1 degree. The maximum mechanical stresses in the mirror have to be minimized. The design calculations use the finite element code ANSYS. The results indicate that the heat input from the plasma can be removed by the coolant flow. Further calculation shave to concern the brazed joints between mirror and cooling block.

  8. Turkey's regulatory plans for high enriched to low enriched conversion of TR-2 reactor core

    International Nuclear Information System (INIS)

    Guelol Oezdere, Oya

    2003-01-01

    Turkey is a developing country and has three nuclear facilities two of which are research reactors and one pilot fuel production plant. One of the two research reactors is TR-2 which is located in Cekmece site in Istanbul. TR-2 Reactor's core is composed of both high enriched and low enriched fuel and from high enriched to low enriched core conversion project will take place in year 2005. This paper presents the plans for drafting regulations on the safety analysis report updates for high enriched to low enriched core conversion of TR-2 reactor, the present regulatory structure of Turkey and licensing activities of nuclear facilities. (author)

  9. Diagnostic system and diagnostic experiences at the Paks Nuclear Power Plant

    International Nuclear Information System (INIS)

    Katona, Tamas

    1986-01-01

    The major functions of the diagnostic system of the first two units of the Paks Nuclear Power Plant are as follows: monitoring the mechanical integrity of the reactor and the primary coolant circuit by means of vibration diagnostics; leakage detection of the primary coolant circuit by means of high frequency sonic analysis; loose parts monitoring based on the analysis of high frequency signals of acceleration detectors; and monitoring the vibration state of the turbines and rotary machines by the latter method or by a procedure based on the detection of mechanical vibrations. Up-to-date vibration diagnostics is based on the information supplied by either acceleration detectors or pressure fluctuation detectors, or in-core and ex-core neutron detectors. (V.N.)

  10. BDI behavior evaluation of an upgraded Monju core and a demonstration core. (1) Plans for the out of pile bundle compressive tests for large diameter pins

    International Nuclear Information System (INIS)

    Ichikawa, Shoichi; Haga, Hiroyuki; Katsuyama, Kozo; Uwaba, Tomoyuki; Maeda, Koji; Nishinoiri, Kenji

    2012-07-01

    The life of FBR (Fast Breeder Reactor) fuel assembly is restricted by BDI (Bundle-Duct Interaction). Therefore, it is very important to carry out the out pile bundle compressive tests which can imitate BDI, in order to evaluate BDI behavior. The target of the conventional BDI behavior was small diameter pins (φ6.5mm) for fuel pellets which were used with the assembly of Monju (the Monju prototype fast breeder reactor) etc. Furthermore by an upgraded Monju core and a demonstration core, adoption of large diameter pins for the holler annular pellets is planned. Therefore, it was necessary to carry out BDI evaluation of a large diameter pin. Then, the plans for out of pile bundle compressive test for large diameter pins were are reported. (author)

  11. Incorporating the Six Core Elements of Health Care Transition Into a Medicaid Managed Care Plan: Lessons Learned From a Pilot Project.

    Science.gov (United States)

    McManus, Margaret; White, Patience; Pirtle, Robin; Hancock, Catina; Ablan, Michael; Corona-Parra, Raquel

    2015-01-01

    This pediatric-to-adult health care transition pilot project describes the process and results of incorporating the "Six Core Elements of Health Care Transition (2.0)" into a Medicaid managed care plan with a group of 35 18-23 year olds who have chronic mental health, developmental, and complex medical conditions. The pilot project demonstrated an effective approach for customizing and delivering recommended transition services. At the start of the 18-month project, the Medicaid plan was at the basic level (1) of transition implementation of the Six Core Elements with no transition policy, member transition readiness assessment results, health care transition plans of care, updated medical summaries, transfer package for the adult-focused provider, and assurance of transfer completion and consumer feedback. At the conclusion of the pilot project, the plan scored at level 3 on each core element. The primary reason for not scoring at the highest level (4) was because the transition elements have not been incorporated into services for all enrollees within the plan. Future efforts in managed care will benefit from starting the transition process much earlier (ages 12-14), expanding the role of nurse care managers and participating pediatric and adult-focused clinicians in transition, and offering payment incentives to clinicians to implement the Six Core Elements of Health Care Transition. Copyright © 2015 Elsevier Inc. All rights reserved.

  12. Comparison of diagnostic classification systems for delirium with new research criteria that incorporate the three core domains.

    Science.gov (United States)

    Trzepacz, Paula T; Meagher, David J; Franco, José G

    2016-05-01

    Diagnostic classification systems do not incorporate phenomenological research findings about the three core symptom domains of delirium (Attentional/Cognitive, Circadian, Higher Level Thinking). We evaluated classification performances of novel Trzepacz, Meagher, and Franco research diagnostic criteria (TMF) that incorporate those domains and ICD-10, DSM-III-R, DSM-IV, and DSM-5. Primary data analysis of 641 patients with mixed neuropsychiatric profiles. Delirium (n=429) and nondelirium (n=212) reference standard groups were identified using cluster analysis of symptoms assessed using the Delirium Rating Scale-Revised-98. Accuracy, sensitivity, specificity, positive and negative predictive values (PPV, NPV), and likelihood ratios (LR+, LR-) are reported. TMF criteria had high sensitivity and specificity (87.4% and 89.2%), more balanced than DSM-III-R (100% and 31.6%), DSM-IV (97.7% and 74.1%), DSM-5 (97.7% and 72.6%), and ICD-10 (66.2% and 100%). PPV of DSM-III-R, DSM-IV, and DSM-5 were 90%. ICD-10 had the lowest NPV (59.4%). TMF had the highest LR+ (8.06) and DSM-III-R the lowest LR- (0.0). Overall, values for DSM-IV and DSM-5 were similar, whereas for ICD-10 and DSM-III-R were inverse of each other. In the pre-existing cognitive impairment/dementia subsample (n=128), TMF retained its highest LR+ though specificity (58.3%) became less well balanced with sensitivity (87.9%), which still exceeded that of DSM. TMF research diagnostic criteria performed well, with more balanced sensitivity and specificity and the highest likelihood ratio for delirium identification. Reflecting the three core domains of delirium, TMF criteria may have advantages in biological research where delineation of this syndrome is important. Copyright © 2016. Published by Elsevier Inc.

  13. Engineering Task Plan for Routine Engineering Support for Core Sampler System

    International Nuclear Information System (INIS)

    BOGER, R.M.

    1999-01-01

    Routine engineering support is required during normal operation of the core sampler trucks and associated ancillary equipment. This engineering support consists of, but is not limited to, troubleshooting operation problems, correcting minor design problems, assistance with work package preparation, assistance with procurement, fabrication shop support, planning of engineering tasks and preparation of associated Engineering Task Plans (ETP) and Engineering Service Requests (ESR). This ETP is the management plan document for implementing routine engineering support. Any additional changes to the scope of this ETP shall require a Letter of Instruction from Lockheed Martin Hanford Corp (LMHC). This document will also be the Work Planning Document for Development Control (HNF 1999a). The scope of this task will be to provide routine engineering support for Characterization equipment as required to support Characterization Operations. A task by task decision will be made by management to determine which tasks will be done per this ETP and if additional ETPs and/or ESRs are required. Due to the unique nature of this task, the only identifiable deliverable is to provide support as requested. Deliverables will be recorded in a task logbook as activities are identified. ESRs will be generated for tasks that require more than 40 person hours to complete, per Characterization Engineering Desk Instructions (DI 1999a)

  14. Monitoring core barrel motion by neutron noise diagnostics

    International Nuclear Information System (INIS)

    Por, G.

    1985-08-01

    The core barrel motion is detected by ionization chambers located around the reactor vessel. The method is based on the measurement of the neutron flux fluctuations. Calculations to determine the direction and the size of the motion are discussed. The identification of core barrel motion and its connection with the error of one of the main circulating pumps in the Rheinsberg nuclear power plant are described. Core barrel motion of 10 Hz with an amplitude less than 50 μm could be diagnozed at the Paks-1 reactor using the Dutch high accuracy evaluation system. (V.N.)

  15. Core Activities Program. TMI-2 Core Receipt and Storage Project Plan

    International Nuclear Information System (INIS)

    Ayers, A.L. Jr.

    1984-12-01

    The TMI-2 Core Receipt and Storage Project is funded by the US Department of Energy and managed by the Technical Support Branch of EG and G Idaho, Inc. at the Idaho National Engineering Laboratory (INEL). As part of the Core Activities Program, this project will include: (a) preparations for receipt and storage of the Three Mile Island Unit 2 core debris at INEL; and (b) receipt and storage operations. This document outlines procedures; project management; safety, environment, and quality; safeguards and security; deliverables; and cost and schedule for the receipt and storage activities at INEL

  16. Evaluation of The Value of Core Needle Biopsy in The Diagnosis of a Breast Mass

    Directory of Open Access Journals (Sweden)

    Asieh Sadat Fattahi

    2016-06-01

    Full Text Available Background: Core needle biopsy (CNB with histological findings is regarded as one of the most important diagnostic measures that make preoperative assessment and planning for appropriate treatment possible. The aim of this study was to determine the sensitivity and specificity of core biopsy results in our patients with benign and malignant breast lumps, especially for borderline breast lesions, by using a classification method.Methods: In this study, 116 patients who were referred to the Surgery Clinic of Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran with breast lump and underwent diagnostic procedures such as mammography and ultrasound were selected. Core needle biopsy (Tru-cut #14 or 16 was performed. After that, excisional biopsy was done. The benign, malignant and unspecified samples obtained by core needle biopsy were evaluated with the samples of the surgical and pathological findings. Then, false positive, false negative, sensitivity, specificity, and diagnostic accuracy of the core needle biopsy method were calculated. Also, the National Health Service Breast Screening Program (NHSBSP classification was employed.Results: The mean age of the participants in this study was 39±13.13 years and the mean tumor size was 2.7 cm. An average of 3.35 biopsies was taken from all patients. Most of the pathology samples taken from CNB and excisional biopsy were compatible with invasive ductal carcinoma. Of the B type classifications, B5 was the most frequent in both methods. Borderline lesions B3 and B4 had a change in their category after surgery. About 2.5% of the samples in core biopsy were inadequate. Skin bruising was the most common core biopsy complication reported. While, the most common complication of excisional biopsy was hematoma. Accuracy, sensitivity, specificity, positive and negative predictive values of the core needle biopsy procedure compared with excisional biopsy was 95.5%, 92.6%, 100%, 100%, and 91

  17. CT-guided transthoracic core needle biopsy for small pulmonary lesions: diagnostic performance and adequacy for molecular testing.

    Science.gov (United States)

    Tian, Panwen; Wang, Ye; Li, Lei; Zhou, Yongzhao; Luo, Wenxin; Li, Weimin

    2017-02-01

    Computed tomography (CT)-guided transthoracic needle biopsy is a well-established, minimally invasive diagnostic tool for pulmonary lesions. Few large studies have been conducted on the diagnostic performance and adequacy for molecular testing of transthoracic core needle biopsy (TCNB) for small pulmonary lesions. This study included CT-guided TCNB with 18-gauge cutting needles in 560 consecutive patients with small (≤3 cm) pulmonary lesions from January 2012 to January 2015. There were 323 males and 237 females, aged 51.8±12.7 years. The size of the pulmonary lesions was 1.8±0.6 cm. The sensitivity, specificity, accuracy and complications of the biopsies were investigated. The risk factors of diagnostic failure were assessed using univariate and multivariate analyses. The sample's adequacy for molecular testing of non-small cell lung cancer (NSCLC) was analyzed. The overall sensitivity, specificity, and accuracy for diagnosis of malignancy were 92.0% (311/338), 98.6% (219/222), and 94.6% (530/560), respectively. The incidence of bleeding complications was 22.9% (128/560), and the incidence of pneumothorax was 10.4% (58/560). Logistic multivariate regression analysis showed that the independent risk factors for diagnostic failure were a lesion size ≤1 cm [odds ratio (OR), 3.95; P=0.007], lower lobe lesions (OR, 2.83; P=0.001), and pneumothorax (OR, 1.98; P=0.004). Genetic analysis was successfully performed on 95.45% (168/176) of specimens diagnosed as NSCLC. At least 96.8% of samples with two or more passes from a lesion were sufficient for molecular testing. The diagnostic yield of small pulmonary lesions by CT-guided TCNB is high, and the procedure is relatively safe. A lesion size ≤1 cm, lower lobe lesions, and pneumothorax are independent risk factors for biopsy diagnostic failure. TCNB specimens could provide adequate tissues for molecular testing.

  18. Major aspects of the design of a first mirror for the ITER core CXRS diagnostics

    International Nuclear Information System (INIS)

    Krasikov, Yury; Panin, Anatoly; Biel, Wolfgang; Krimmer, Andreas; Litnovsky, Andrey; Mertens, Philippe; Neubauer, Olaf; Schrader, Michael

    2015-01-01

    Highlights: • Availability, technological issues, and changes in the ScMo structure to be solved in future. • Developed passively cooled mirror is a workable, flexible, scalable and robust concept. • The generic upper port plug is to be considerable customized. - Abstract: The ITER core charge exchange recombination spectroscopy diagnostics (cCXRS) occupies the vacuum vessel upper port #3 and includes, in its generic version, the following in-vessel components: an optical mirror system, a shutter, the diagnostic first wall and the neutron shielding block. The most vulnerable diagnostic mirror is obviously the first one (M1) directly observing the plasma. The M1 reference option is made of a single crystalline molybdenum (ScMo). The paper indicates major aspects influencing the first mirror design and identifies the most reasonable and reliable concept for cCXRS M1 at present. The applicability of the option presented is determined by many reasons, and especially, by the ITER generic upper port plug and its customization flexibility. The largest dimension of the mirror polished face is ∼300 mm. Such large ScMo workpieces are currently not available on the market. The mirror should be designed as an assembly of several ScMo pieces joined together. The M1 design is supported by multifield thermal, electromagnetic and structural analyses. The performed study confirms the feasibility of the proposed solutions. At the same time, the paper indicates numerous technological issues of the M1 unit to be solved in future.

  19. Major aspects of the design of a first mirror for the ITER core CXRS diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Krasikov, Yury, E-mail: y.krasikov@fz-juelich.de; Panin, Anatoly; Biel, Wolfgang; Krimmer, Andreas; Litnovsky, Andrey; Mertens, Philippe; Neubauer, Olaf; Schrader, Michael

    2015-10-15

    Highlights: • Availability, technological issues, and changes in the ScMo structure to be solved in future. • Developed passively cooled mirror is a workable, flexible, scalable and robust concept. • The generic upper port plug is to be considerable customized. - Abstract: The ITER core charge exchange recombination spectroscopy diagnostics (cCXRS) occupies the vacuum vessel upper port #3 and includes, in its generic version, the following in-vessel components: an optical mirror system, a shutter, the diagnostic first wall and the neutron shielding block. The most vulnerable diagnostic mirror is obviously the first one (M1) directly observing the plasma. The M1 reference option is made of a single crystalline molybdenum (ScMo). The paper indicates major aspects influencing the first mirror design and identifies the most reasonable and reliable concept for cCXRS M1 at present. The applicability of the option presented is determined by many reasons, and especially, by the ITER generic upper port plug and its customization flexibility. The largest dimension of the mirror polished face is ∼300 mm. Such large ScMo workpieces are currently not available on the market. The mirror should be designed as an assembly of several ScMo pieces joined together. The M1 design is supported by multifield thermal, electromagnetic and structural analyses. The performed study confirms the feasibility of the proposed solutions. At the same time, the paper indicates numerous technological issues of the M1 unit to be solved in future.

  20. New patient pathway using vacuum-assisted biopsy reduces diagnostic surgery for B3 lesions

    International Nuclear Information System (INIS)

    Rajan, S.; Shaaban, A.M.; Dall, B.J.G.; Sharma, N.

    2012-01-01

    Aim: To assess the clinical impact of a new patient management pathway incorporating vacuum-assisted biopsy for lesions of uncertain malignant potential (B3). Materials and methods: A retrospective analysis was undertaken of all B3 lesions on core biopsy in the pathology database from April 2008 to April 2010. Outcome measures assessed included final histological diagnosis, frequency of diagnostic surgical biopsy, and impact on management. Results: In the old pathway, there were 95 B3 lesions, of which 14% (13/95) were planned for vacuum-assisted biopsy and 86% (82/95) for surgical biopsy. In the new pathway, there were 94 B3 lesions, of which 68% (64/94) were planned for vacuum-assisted biopsy and 32% (30/94) for surgical biopsy. Following further sampling with vacuum-assisted biopsy, only 13% of patients required diagnostic surgical biopsy and in 25% of cases, a preoperative diagnosis of carcinoma was reached allowing patients to proceed to therapeutic surgery. Conclusion: The new pathway has reduced the number of benign diagnostic surgical biopsies performed and increased the preoperative diagnosis of breast cancer.

  1. Tank 241-AY-101 Privatization Push Mode Core Sampling and Analysis Plan

    International Nuclear Information System (INIS)

    TEMPLETON, A.M.

    2000-01-01

    This sampling and analysis plan (SAP) identifies characterization objectives pertaining to sample collection, laboratory analytical evaluation, and reporting requirements for samples obtained from tank 241-AY-101. The purpose of this sampling event is to obtain information about the characteristics of the contents of 241-AY-101 required to satisfy Data Quality Objectives For RPP Privatization Phase I: Confirm Tank T Is An Appropriate Feed Source For High-Level Waste Feed Batch X(HLW DQO) (Nguyen 1999a), Data Quality Objectives For TWRS Privatization Phase I : Confirm Tank T Is An Appropriate Feed Source For Low-Activity Waste Feed Batch X (LAW DQO) (Nguyen 1999b), Low Activity Waste and High-Level Waste Feed Data Quality Objectives (L and H DQO) (Patello et al. 1999), and Characterization Data Needs for Development, Design, and Operation of Retrieval Equipment Developed through the Data Quality Objective Process (Equipment DQO) (Bloom 1996). Special instructions regarding support to the LAW and HLW DQOs are provided by Baldwin (1999). Push mode core samples will be obtained from risers 15G and 150 to provide sufficient material for the chemical analyses and tests required to satisfy these data quality objectives. The 222-S Laboratory will extrude core samples; composite the liquids and solids; perform chemical analyses on composite and segment samples; archive half-segment samples; and provide subsamples to the Process Chemistry Laboratory. The Process Chemistry Laboratory will prepare test plans and perform process tests to evaluate the behavior of the 241-AY-101 waste undergoing the retrieval and treatment scenarios defined in the applicable DQOs. Requirements for analyses of samples originating in the process tests will be documented in the corresponding test plans and are not within the scope of this SAP

  2. Tank 241-AY-101 Privatization Push Mode Core Sampling and Analysis Plan

    International Nuclear Information System (INIS)

    TEMPLETON, A.M.

    2000-01-01

    This sampling and analysis plan (SAP) identifies characterization objectives pertaining to sample collection, laboratory analytical evaluation, and reporting requirements for samples obtained from tank 241-AY-101. The purpose of this sampling event is to obtain information about the characteristics of the contents of 241-AY-101 required to satisfy ''Data Quality Objectives For RPP Privatization Phase I: Confirm Tank T Is An Appropriate Feed Source For High-Level Waste Feed Batch X(HLW DQO)' (Nguyen 1999a), ''Data Quality Objectives For TWRS Privatization Phase I: Confirm Tank T Is An Appropriate Feed Source For Low-Activity Waste Feed Butch X (LAW DQO) (Nguyen 1999b)'', ''Low Activity Waste and High-Level Waste Feed Data Quality Objectives (L and H DQO)'' (Patello et al. 1999), and ''Characterization Data Needs for Development, Design, and Operation of Retrieval Equipment Developed through the Data Quality Objective Process (Equipment DQO)'' (Bloom 1996). Special instructions regarding support to the LAW and HLW DQOs are provided by Baldwin (1999). Push mode core samples will be obtained from risers 15G and 150 to provide sufficient material for the chemical analyses and tests required to satisfy these data quality objectives. The 222-S Laboratory will extrude core samples; composite the liquids and solids; perform chemical analyses on composite and segment samples; archive half-segment samples; and provide sub-samples to the Process Chemistry Laboratory. The Process Chemistry Laboratory will prepare test plans and perform process tests to evaluate the behavior of the 241-AY-101 waste undergoing the retrieval and treatment scenarios defined in the applicable DQOs. Requirements for analyses of samples originating in the process tests will be documented in the corresponding test plans and are not within the scope of this SAP

  3. Diagnostic performance of power doppler and ultrasound contrast agents in early imaging-based diagnosis of organ-confined prostate cancer: Is it possible to spare cores with contrast-guided biopsy?

    Energy Technology Data Exchange (ETDEWEB)

    Delgado Oliva, F., E-mail: frandelgol@hotmail.com; Arlandis Guzman, S.; Bonillo García, M.; Broseta Rico, E.; Boronat Tormo, F.

    2016-10-15

    % vs. 35%), and stage cT2 (43.5% vs. 66.6%), with a p value < 0.05. Following the “core-by-core” analysis, the detection rates by core of CEUS-targeted biopsy versus randomized biopsy were: Global population (16% vs. 13%), stage cT1 (30.3% vs. 28%), and stage cT2 (48% vs. 37%), with a p value > 0.05. The NNT for CEUS-targeted biopsy was 83.3. Conclusions: The low sensitivity, specificity, positive predictive and negative predictive values of gray scale-B-mode, PDUS and CEUS represent scant diagnostic performance of these variables in prostate cancer detection. Prostate cancer detection rates yielded by randomized biopsy were superior than the detection rate of targeted biopsy using B-mode, PDUS and CEUS; as a result, randomized biopsy versus CEUS-targeted biopsies cannot be excluded from biopsy strategy plans for the diagnosis of prostate cancer.

  4. Diagnostic performance of power doppler and ultrasound contrast agents in early imaging-based diagnosis of organ-confined prostate cancer: Is it possible to spare cores with contrast-guided biopsy?

    International Nuclear Information System (INIS)

    Delgado Oliva, F.; Arlandis Guzman, S.; Bonillo García, M.; Broseta Rico, E.; Boronat Tormo, F.

    2016-01-01

    % vs. 35%), and stage cT2 (43.5% vs. 66.6%), with a p value < 0.05. Following the “core-by-core” analysis, the detection rates by core of CEUS-targeted biopsy versus randomized biopsy were: Global population (16% vs. 13%), stage cT1 (30.3% vs. 28%), and stage cT2 (48% vs. 37%), with a p value > 0.05. The NNT for CEUS-targeted biopsy was 83.3. Conclusions: The low sensitivity, specificity, positive predictive and negative predictive values of gray scale-B-mode, PDUS and CEUS represent scant diagnostic performance of these variables in prostate cancer detection. Prostate cancer detection rates yielded by randomized biopsy were superior than the detection rate of targeted biopsy using B-mode, PDUS and CEUS; as a result, randomized biopsy versus CEUS-targeted biopsies cannot be excluded from biopsy strategy plans for the diagnosis of prostate cancer.

  5. An expert system for PWR core operation management

    Energy Technology Data Exchange (ETDEWEB)

    Ida, Toshio; Masuda, Masahiro; Nishioka, Hiromasa

    1988-01-01

    Planning for restartup after planned or unplanned reactor shutdown and load-follow operations is an important task in the core operation management of pressurized water reactors (PWRs). These planning problems have been solved by planning experts using their expertise and the computational prediction of core behavior. Therefore, the quality of the plan and the time consumed in the planning depend heavily on the skillfulness of the planning experts. A knowledge engineering approach has been recently considered as a promising means to solve such complicated planning problems. Many knowledge-based systems have been developed so far, and some of them have already been applied because of their effectiveness. The expert system REPLEX has been developed to aid core management engineers in making a successful plan for the restartup or the load-follow operation of PWRs within a shorter time. It can maintain planning tasks at a high-quality level independent of the skillfulness of core management engineers and enhance the efficiency of management. REPLEX has an explanation function that helps user understanding of plans. It could be a useful took, therefore, for the training of core management engineers.

  6. An expert system for PWR core operation management

    International Nuclear Information System (INIS)

    Ida, Toshio; Masuda, Masahiro; Nishioka, Hiromasa.

    1988-01-01

    Planning for restartup after planned or unplanned reactor shutdown and load-follow operations is an important task in the core operation management of pressurized water reactors (PWRs). These planning problems have been solved by planning experts using their expertise and the computational prediction of core behavior. Therefore, the quality of the plan and the time consumed in the planning depend heavily on the skillfulness of the planning experts. A knowledge engineering approach has been recently considered as a promising means to solve such complicated planning problems. Many knowledge-based systems have been developed so far, and some of them have already been applied because of their effectiveness. The expert system REPLEX has been developed to aid core management engineers in making a successful plan for the restartup or the load-follow operation of PWRs within a shorter time. It can maintain planning tasks at a high-quality level independent of the skillfulness of core management engineers and enhance the efficiency of management. REPLEX has an explanation function that helps user understanding of plans. It could be a useful took, therefore, for the training of core management engineers

  7. Test plan: Air intake shaft performance test -- Addendum for obtaining cores in the Culebra for radionuclide retardation studies

    International Nuclear Information System (INIS)

    Gelbard, F.

    1991-10-01

    Core samples are needed for obtaining data on radionuclide retardation. The cores will be used to first determine local basic properties of Culebra rock such as permeability, structural integrity, fracture spacing, and fracture size. These quantities will then be used to design a laboratory experimental program to determine radionuclide retardation in a column flow apparatus using the cores obtained in this project. This addendum covers only the coring activities necessary to retrieve Culebra cores. The laboratory work will be documented in a separate test plan. It is anticipated that Culebra rock samples will be highly fractured, with a fracture spacing on the order of 2 to 3 inches To obtain representative core samples that are intact, horizontal cores about 6 inches in diameter and several feet long will be needed. These cores will provide a good indication of Culebra rock fracturing and provide several samples needed to conduct column flow experiments. If the rock is so fractured that only rubble is obtained, then the rubble will be used in the column experiments. In addition, as a byproduct of the coring operation, natural groundwater collected from the holes will be used to develop a synthetic brine for the laboratory experiments

  8. Utilizing benchmark data from the ANL-ZPR diagnostic cores program

    International Nuclear Information System (INIS)

    Schaefer, R. W.; McKnight, R. D.

    2000-01-01

    The support of the criticality safety community is allowing the production of benchmark descriptions of several assemblies from the ZPR Diagnostic Cores Program. The assemblies have high sensitivities to nuclear data for a few isotopes. This can highlight limitations in nuclear data for selected nuclides or in standard methods used to treat these data. The present work extends the use of the simplified model of the U9 benchmark assembly beyond the validation of k eff . Further simplifications have been made to produce a data testing benchmark in the style of the standard CSEWG benchmark specifications. Calculations for this data testing benchmark are compared to results obtained with more detailed models and methods to determine their biases. These biases or corrections factors can then be applied in the use of the less refined methods and models. Data testing results using Versions IV, V, and VI of the ENDF/B nuclear data are presented for k eff , f 28 /f 25 , c 28 /f 25 , and β eff . These limited results demonstrate the importance of studying other integral parameters in addition to k eff in trying to improve nuclear data and methods and the importance of accounting for methods and/or modeling biases when using data testing results to infer the quality of the nuclear data files

  9. Reactor core operation management system

    International Nuclear Information System (INIS)

    Sato, Tomomi.

    1992-01-01

    Among operations of periodical inspection for a nuclear power plant, sequence, time and safety rule, as well as necessary equipments and the number thereof required for each of the operation are determined previously for given operation plannings, relevant to the reactor core operations. Operation items relative to each of coordinates of the reactor core are retrieved and arranged based on specified conditions, to use the operation equipments effectively. Further, a combination of operations, relative to the reactor core coordinates with no physical interference and shortest in accordance with safety rules is judged, and the order and the step of the operation relevant to the entire reactor core operations are planned. After the start of the operation, the necessity for changing the operation sequence is judged depending on the judgement as to whether it is conducted according to the safety rule and the deviation between the plan and the result, based on the information for the progress of each of the operations. Alternatively, the operation sequence and the step to be changed are planned again in accordance with the requirement for the change of the operation planning. Then, the shortest operation time can be planned depending on the simultaneous operation impossible condition and the condition for the operation time zone determined by labor conditions. (N.H.)

  10. Reactor core operation management system

    Energy Technology Data Exchange (ETDEWEB)

    Sato, Tomomi.

    1992-05-28

    Among operations of periodical inspection for a nuclear power plant, sequence, time and safety rule, as well as necessary equipments and the number thereof required for each of the operation are determined previously for given operation plannings, relevant to the reactor core operations. Operation items relative to each of coordinates of the reactor core are retrieved and arranged based on specified conditions, to use the operation equipments effectively. Further, a combination of operations, relative to the reactor core coordinates with no physical interference and shortest in accordance with safety rules is judged, and the order and the step of the operation relevant to the entire reactor core operations are planned. After the start of the operation, the necessity for changing the operation sequence is judged depending on the judgement as to whether it is conducted according to the safety rule and the deviation between the plan and the result, based on the information for the progress of each of the operations. Alternatively, the operation sequence and the step to be changed are planned again in accordance with the requirement for the change of the operation planning. Then, the shortest operation time can be planned depending on the simultaneous operation impossible condition and the condition for the operation time zone determined by labor conditions. (N.H.).

  11. ACVP-02: Plasma SIV/SHIV RNA Viral Load Measurements through the AIDS and Cancer Virus Program Quantitative Molecular Diagnostics Core | Frederick National Laboratory for Cancer Research

    Science.gov (United States)

    The SIV plasma viral load assay performed by the Quantitative Molecular Diagnostics Core (QMDC) utilizes reagents specifically designed to detect and accurately quantify the full range of SIV/SHIV viral variants and clones in common usage in the rese

  12. Quality of Diagnosis and Treatment Plans After Using the 'Diagnostic Guideline for Anxiety and Challenging Behaviours' in People with Intellectual Disabilities: A Comparative Multiple Case Study Design.

    Science.gov (United States)

    Pruijssers, Addy; van Meijel, Berno; Maaskant, Marian; Keeman, Noortje; van Achterberg, Theo

    2016-07-01

    People with intellectual disabilities often have a multitude of concurrent problems due to the combination of cognitive impairments, psychiatric disorders (particularly anxiety) and related challenging behaviours. Diagnoses in people with intellectual disabilities are complicated. This study evaluates the quality of the diagnoses and treatment plans after using a guideline that was developed to support professionals in their diagnostic tasks. A comparative multiple case study with an experimental and control condition, applying deductive analyses of diagnoses and treatment plans. The analyses revealed that the number of diagnostic statements and planned treatment actions in the experimental group was significantly larger and more differentiated than in the control condition. In the control group, consequential harm and protective factors were hardly mentioned in diagnoses and treatment plans. Working with the 'Diagnostic Guideline for Anxiety and CB' leads to improved diagnoses and treatment plans compared with care as usual. © 2015 John Wiley & Sons Ltd.

  13. Planning and Execution of a Marine Methane Hydrate Pressure Coring Program for the Walker Ridge and Green Canyon Areas of the Gulf of Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Humphrey, Gary [Fugro Geoconsulting Inc., Houston, TX (United States)

    2015-09-14

    The objective of this project (and report) is to produce a guide to developing scientific, operational, and logistical plans for a future methane hydrate-focused offshore pressure coring program. This report focuses primarily on a potential coring program in the Walker Ridge 313 and Green Canyon 955 blocks where previous investigations were undertaken as part of the 2009 Department of Energy JIP Leg II expedition, however, the approach to designing a pressure coring program that was utilized for this project may also serve as a useful model for planning pressure coring programs for hydrates in other areas. The initial portion of the report provides a brief overview of prior investigations related to gas hydrates in general and at the Walker Ridge 313 and Green Canyon 955 blocks in particular. The main content of the report provides guidance for various criteria that will come into play when designing a pressure coring program.

  14. Reviewing the quality of strategic environmental assessment reports for English spatial plan core strategies

    International Nuclear Information System (INIS)

    Fischer, Thomas B.

    2010-01-01

    This paper summarises the results of a research project from early 2008, involving the author of this paper, as well as 18 post-graduate University of Liverpool students, in which the quality of European Directive based strategic environmental assessment (SEA) reports of English spatial plan core strategies (conducted within the context of the spatial planning sustainability appraisal-SA-regime) was reviewed. The project aimed at establishing the extensiveness of emerging spatial plan related SEA practice, as well as highlighting shortcomings and problems. Overall, it was found that whilst some aspects of assessment were done well, others were not of a satisfactory quality. Shortcomings were connected particularly with the practice of listing potentially relevant baseline documents and data without distinguishing sufficiently between those that are important in terms of significant impacts and those that are not. Problems were also found to exist with the evaluation of options and impacts, the consideration of substantive aspects, such as health, as well as regarding the formulation of final recommendations and monitoring.

  15. Accessible or Inaccessible? Diagnostic Efficacy of CT-Guided Core Biopsies of Head and Neck Masses

    Energy Technology Data Exchange (ETDEWEB)

    Cunningham, Jane D., E-mail: janecunningham0708@gmail.com; McCusker, Mark W.; Power, Sarah; PearlyTi, Joanna; Thornton, John; Brennan, Paul; Lee, Michael J.; O’Hare, Alan; Looby, Seamus [Beaumont Hospital, Department of Radiology (Ireland)

    2015-04-15

    PurposeTissue sampling of lesions in the head and neck is challenging due to complex regional anatomy and sometimes necessitates open surgical biopsy. However, many patients are poor surgical candidates due to comorbidity. Thus, we evaluated the use of CT guidance for establishing histopathological diagnosis of head and neck masses.MethodsAll consecutive patients (n = 22) who underwent CT-guided core biopsy of head or neck masses between April 2009 and August 2012 were retrospectively reviewed using the departmental CT interventional procedures database. The indication for each biopsy performed was to establish or exclude a diagnosis of neoplasia in patients with suspicious head or neck lesions found on clinical examination or imaging studies. Patients received conscious sedation and 18 G, semiautomated core needle biopsies were performed by experienced neuroradiologists using 16-slice multidetector row CT imaging guidance (Somatom Definition Siemens Medical Solutions, Germany). Histopathology results of each biopsy were analysed.ResultsSixteen of 22 biopsies that were performed (73 %) yielded a pathological diagnosis. Anatomic locations biopsied included: masticator (n = 7), parapharyngeal (n = 3), parotid (n = 3), carotid (n = 3), perivertebral (n = 3), pharyngeal (n = 2), and retropharyngeal (n = 1) spaces. Six biopsies (27 %) were nondiagnostic due to inadequate tissue sampling, particularly small biopsy sample size and failure to biopsy the true sampling site due to extensive necrosis. No major complications were encountered.ConclusionsThe use of CT guidance to perform core biopsies of head and neck masses is an effective means of establishing histopathological diagnosis and reduces the need for diagnostic open surgical biopsy and general anaesthesia.

  16. Detection of HCV core antigen and its diagnostic significance

    Directory of Open Access Journals (Sweden)

    YANG Jie

    2013-02-01

    Full Text Available ObjectiveTo compare the abilities of the hepatitis C virus (HCV core antigen (cAg test and the HCV RNA assay for confirming anti-HCV presence in order to determine the clinical utility of the HCV-cAg as an alternative or confirmatory diagnostic tool. MethodsSerum samples collected from 158 patients diagnosed with HCV infection were subjected to the enzyme-linked immunosorbent assay-based HCV-cAg test. The optical density (OD measured values were used to calculate the ratio of specimen absorbance to the cutoff value (S/CO. Simultaneously, the serum samples were subjected to PCR-based nucleic acid amplification quantitative fluorescence detection of HCV RNA. ResultsNone of the serum samples had a S/CO value <1 for the HCV-cAg test (100% negative, but all of the samples had a S/CO value >5 (100% positive. The HCV-cAg test sensitivity was 87.05%, specificity was 76.67%, positive predictive value was 9653%, and negative predictive value was 44.23%. As the S/CO value gradually increased, the significantly higher positive coincident rate of the HCV RNA test decreased. The HCV RNA negative coincident rate was significantly higher than that of the HCV-cAg test. HCV-cAg S/CO values between 1 and 2 corresponded to an HCV RNA values between 1.0×103 copies/ml and 1.0×104 copies/ml. The highest S/CO value obtained was 1.992. ConclusionThe HCV-cAg test is comparable to the HCV RNA assay for diagnosing HCV infection.

  17. Test plan for core drilling ignitability testing

    International Nuclear Information System (INIS)

    Witwer, K.S.

    1996-01-01

    The objective of this testing is to determine if ignition occurs while core drilling in a flammable gas environment. Drilling parameters are chosen so as to provide bounding conditions for the core sampling environment. If ignition does not occur under the conditions set forth in this test, then a satisfactory level of confidence will be obtained which would allow field operations under the normal drilling conditions

  18. Relating DSM-5 section II and section III personality disorder diagnostic classification systems to treatment planning.

    Science.gov (United States)

    Morey, Leslie C; Benson, Kathryn T

    2016-07-01

    Beginning with DSM-III, the inclusion of a "personality" axis was designed to encourage awareness of personality disorders and the treatment-related implications of individual differences, but since that time there is little accumulated evidence that the personality disorder categories provide substantial treatment-related guidance. The DSM-5 Personality and Personality Disorders Work Group sought to develop an Alternative Model for personality disorder, and this study examined whether this model is more closely related to clinicians' decision-making processes than the traditional categorical personality disorder diagnoses. A national sample of 337 clinicians provided complete personality disorder diagnostic information and several treatment-related clinical judgments about one of their patients. The dimensional concepts of the DSM-5 Alternative Model for personality disorders demonstrated stronger relationships than categorical DSM-IV/DSM-5 Section II diagnoses to 10 of 11 clinical judgments regarding differential treatment planning, optimal treatment intensity, and long-term prognosis. The constructs of the DSM-5 Alternative Model for personality disorders may provide more clinically useful information for treatment planning than the official categorical personality disorder diagnostic system retained in DSM-5 Section II. Copyright © 2016 Elsevier Inc. All rights reserved.

  19. Tank 241-AZ-102 Privatization Push Mode Core Sampling and Analysis Plan

    International Nuclear Information System (INIS)

    RASMUSSEN, J.H.

    1999-01-01

    This sampling and analysis plan (SAP) identifies characterization objectives pertaining to sample collection, laboratory analytical evaluation, and reporting requirements for samples obtained from tank 241-AZ-102. The purpose of this sampling event is to obtain information about the characteristics of the contents of 241-AZ-102 required to satisfy the Data Quality Objectives For TWRS Privatization Phase I : Confirm Tank TIS An Appropriate Feed Source For High-Level Waste Feed Batch X(HLW DQO) (Nguyen 1999a), Data Quality Objectives For TWRS Privatization Phase 1: Confirm Tank TIS An Appropriate Feed Source For Low-Activity Waste Feed Batch X (LAW DQO) (Nguyen 1999b), Low Activity Waste and High Level Waste Feed Data Quality Objectives (L and H DQO) (Patello et al. 1999) and Characterization Data Needs for Development, Design, and Operation of Retrieval Equipment Developed through the Data Quality Objective Process (Equipment DQO) (Bloom 1996). The Tank Characterization Technical Sampling Basis document (Brown et al. 1998) indicates that these issues, except the Equipment DQO apply to tank 241-AZ-102 for this sampling event. The Equipment DQO is applied for shear strength measurements of the solids segments only. Poppiti (1999) requires additional americium-241 analyses of the sludge segments. Brown et al. (1998) also identify safety screening, regulatory issues and provision of samples to the Privatization Contractor(s) as applicable issues for this tank. However, these issues will not be addressed via this sampling event. Reynolds et al. (1999) concluded that information from previous sampling events was sufficient to satisfy the safety screening requirements for tank 241-AZ-102. Push mode core samples will be obtained from risers 15C and 24A to provide sufficient material for the chemical analyses and tests required to satisfy these data quality objectives. The 222-S Laboratory will extrude core samples, composite the liquids and solids, perform chemical analyses

  20. Internet plan and planning

    Directory of Open Access Journals (Sweden)

    Kahriman Emina

    2008-01-01

    Full Text Available Paper discuss specific features of internet plan as well as planning as management process in general in the contemporary environment. No need to stress out that marketing plan and marketing planning is core activity in approaching to market. At the same time, there are a lot specific c request in preparing marketing plan comparing to business planning due to marketing plan is an essential part. The importance of internet plan and planning rely on specific features of the internet network but as a part of general corporate as well as marketing strategy.

  1. Engineering task plan for upgrades to the leveling jacks on core sample trucks number 3 and 4; TOPICAL

    International Nuclear Information System (INIS)

    KOSTELNIK, A.J.

    1999-01-01

    Characterizing the waste in underground storage tanks at the Hanford Site is accomplished by obtaining a representative core sample for analysis. Core sampling is one of the numerous techniques that have been developed for use given the environmental and field conditions at the Hanford Site. Core sampling is currently accomplished using either Push Mode Core Sample Truck No.1 or; Rotary Mode Core Sample Trucks No.2, 3 or 4. Past analysis (WHC 1994) has indicated that the Core Sample Truck (CST) leveling jacks are structurally inadequate when lateral loads are applied. WHC 1994 identifies many areas where failure could occur. All these failures are based on exceeding the allowable stresses listed in the American Institute of Steel Construction (AISC) code. The mode of failure is for the outrigger attachments to the truck frame to fail resulting in dropping of the CST and possible overturning (Ref. Ziada and Hundal, 1996). Out of level deployment of the truck can exceed the code allowable stresses in the structure. Calculations have been performed to establish limits for maintaining the truck level when lifting. The calculations and the associated limits are included in appendix A. The need for future operations of the CSTS is limited. Sampling is expected to be complete in FY-2001. Since there is limited time at risk for continued use of the CSTS with the leveling controls without correcting the structural problems, there are several design changes that could give incremental improvements to the operational safety of the CSTS with limited impact on available operating time. The improvements focus on making the truck easier to control during lifting and leveling. Not all of the tasks identified in this ETP need to be performed. Each task alone can improve the safety. This engineering task plan is the management plan document for implementing the necessary additional structural analysis. Any additional changes to meet requirements of standing orders shall require a

  2. DIM and diagnostic placement for NIF experiments

    International Nuclear Information System (INIS)

    Kalantar, D.

    1999-01-01

    The input that has been provided on the NIF experiment setup sheets has allowed us to review the diagnostic and DIM placement as well as the baseline unconverted light management plan. We have done an iteration to identify common diagnostic lines of sight, and with additional requirements defined by specific experiments, we propose (1) a baseline plan for DIM placement requiring only five DIMs that may be moved between up to seven DIM ports, and (2) a modified baseline unconverted light management plan. We request additional input to identify primary vs. secondary diagnostics for each experiment definition

  3. The diagnostic ability of an additional midline peripheral zone biopsy in transrectal ultrasonography-guided 12-core prostate biopsy to detect midline prostate cancer

    Directory of Open Access Journals (Sweden)

    Inpyeong Hwang

    2016-01-01

    Full Text Available Purpose: The goal of this study was to evaluate the diagnostic effect of adding a midline peripheral zone (PZ biopsy to the 12-core biopsy protocol used to diagnose prostate cancer (PC, and to assess the clinical and pathologic characteristics of midline-positive PC in order to identify a potential subgroup of patients who would require midline PZ biopsy. Methods: This study included 741 consecutive patients who underwent a transrectal ultrasonography-guided, 12-core prostate biopsy with an additional midline core biopsy between October 2012 and December 2013. We grouped patients by the presence or absence of PC and subdivided patients with PC based on the involvement of the midline core. The clinical characteristics of these groups were compared, including serum prostate-specific antigen (PSA concentrations, PSA density, and pathological features in the biopsy specimens. Results: PC was detected in 289 patients (39.0%. Among the PC patients, 66 patients (22.8% had midline PC. No patients were diagnosed with PC based only on a midline core. The Gleason scores, number of positive cores, tumor core length, serum PSA concentrations, and PSA density were significantly higher in patients with midline-positive PC (P<0.001. Furthermore, significant cancer was more frequent in the midline-positive group (98.5% vs. 78.0%. Conclusion: Patients showing a positive result for PC in a midline PZ biopsy were more likely to have multiple tumors or large-volume PC with a high tumor burden. However, our data indicated that an additional midline core biopsy is unlikely to be helpful in detecting occult midline PC.

  4. The C's of Our Sea Change: Plans for Training Staff, from Core Competencies to Learning 2.0

    Science.gov (United States)

    Blowers, Helene; Reed, Lori

    2007-01-01

    This article explains a two-part plan, created by the people at the Public Library of Charlotte & Mecklenburg County (PLCMC), to help staff members keep up with the sea change of technology. A core competencies training program was developed. This keeps workers afloat by providing them with the technology skills they need to support the change…

  5. Engineering task plan for the annual revision of the rotary mode core sampling system safety equipment list

    International Nuclear Information System (INIS)

    BOGER, R.M.

    1999-01-01

    This Engineering Task Plan addresses an effort to provide an update to the RMCS Systems 3 and 4 SEL and DCM in order to incorporate the changes to the authorization basis implemented by HNF-SD-WM-BIO-001, Rev. 0 (Draft), Addendum 5 , Safety Analysis for Rotary Mode Core Sampling. Responsibilities, task description, cost estimate, and schedule are presented

  6. Tank 241-SX-105 rotary mode core sampling and analysis plan

    International Nuclear Information System (INIS)

    Simpson, B.C.

    1998-01-01

    This sampling and analysis plan (SAP) identifies characterization objectives pertaining to sample collection, laboratory analytical evaluation, and reporting requirements for rotary mode core samples from tank 241-SX-105 (SX-105). It is written in accordance with Tank Safety Screening Data Quality Objective (Dukelow et al. 1995) and Memorandum of Understanding for the Organic Complexant Safety Issue Data Requirements (Schreiber 1997a). Vapor screening issues apply as well, but are outside the scope of this SAP. A physical profile prediction based on waste fill history and previous sampling information is provided in Appendix A. Prior to core sampling, the dome space (below the riser) shall be measured for the presence of flammable gases. The measurement shall be taken from within the dome space and the data reported as a percentage of the lower flammability limit (LFL). The results shall be transmitted to the tank coordinator within ten working days of the sampling event (Schreiber 1997b). If the results are above 25 percent of the LFL when analyzing by gas chromatography/mass spectrometry or gas-specific monitoring gauges or above 10% of the LFL when analyzing with a combustible gas meter, the necessity for recurring sampling for flammable gas concentration and the frequency of such sampling will be determined by the Flammable Gas Safety Project. Any additional vapor sampling is not within the scope of this SAP

  7. Design advances of the Core Plasma Thomson Scattering diagnostic for ITER.

    Czech Academy of Sciences Publication Activity Database

    Scannell, R.; Maslov, M.; Naylor, G.; O’Gorman, T.; Kempenaars, M.; Carr, M.; Bílková, Petra; Böhm, Petr; Giudicotti, L.; Pasqualotto, R.; Bassan, M.; Vayakis, G.; Walsh, M.; Huxford, R.

    2017-01-01

    Roč. 12, November (2017), č. článku C11010. ISSN 1748-0221. [International Symposium on Laser-Aided Plasma Diagnostics (LAPD2017) /18./. Prague, 24.09.2017-28.09.2017] Institutional support: RVO:61389021 Keywords : Nuclear instruments and methods for hot plasma diagnostics * Plasma diagnostics - interferometry * spectroscopy and imaging Subject RIV: BL - Plasma and Gas Discharge Physics OBOR OECD: 2.11 Other engineering and technologies Impact factor: 1.220, year: 2016 http://iopscience.iop.org/article/10.1088/1748-0221/12/11/C11010/pdf

  8. Discussion and Reflection on Several Core Issues in the Grand Canal Heritage Conservation Planning Under the Background of Application for World Heritage

    Directory of Open Access Journals (Sweden)

    D. Yao

    2015-08-01

    Full Text Available At the turn of the century, a series of new heritage concepts have appeared in the area of international cultural heritage protection, such as cultural landscape, cultural route, heritage corridor, heritage canal, which presents the development of people’s recognition of cultural heritage. According to The Operational Guidelines for the Implementation of the World Heritage Convention, management planning must be contained in the material used to apply for world heritage. The State Administration of Cultural Heritage designed the mission and work schedule of China’s Grand Canal conservation planning in 2008. This research will introduce the working system of China’s Grand Canal conservation planning on three levels: city, province and nation. It will also summarize the characteristics of the core technologies in China’s Grand Canal conservation planning, including key issues like the identification of the core characteristic of China’s Grand Canal, value assessment and determination of the protection scope. Through reviewing, thinking and analyzing the previous accomplishments, the research will offer some advices for the similar world heritage conservation planning after.

  9. Molecular Diagnostics of the Internal Motions of Massive Cores

    Science.gov (United States)

    Pineda, Jorge; Velusamy, T.; Goldsmith, P.; Li, D.; Peng, R.; Langer, W.

    2009-12-01

    We present models of the internal kinematics of massive cores in the Orion molecular cloud. We use a sample of cores studied by Velusamy et al. (2008) that show red, blue, and no asymmetry in their HCO+ line profiles in equal proportion, and which therefore may represent a sample of cores in different kinematic states. We use the radiative transfer code RATRAN (Hogerheijde & van der Tak 2000) to model several transitions of HCO+ and H13CO+ as well as the dust continuum emission, of a spherical model cloud with radial density, temperature, and velocity gradients. We find that an excitation and velocity gradients are prerequisites to reproduce the observed line profiles. We use the dust continuum emission to constrain the density and temperature gradients. This allows us to narrow down the functional forms of the velocity gradient giving us the opportunity to test several theoretical predictions of velocity gradients produced by the effect of magnetic fields (e.g. Tassis et. al. 2007) and turbulence (e.g. Vasquez-Semanedi et al 2007).

  10. Diagnostic performance of power doppler and ultrasound contrast agents in early imaging-based diagnosis of organ-confined prostate cancer: Is it possible to spare cores with contrast-guided biopsy?

    Science.gov (United States)

    Delgado Oliva, F; Arlandis Guzman, S; Bonillo García, M; Broseta Rico, E; Boronat Tormo, F

    2016-10-01

    To evaluate the diagnostic performance of gray scale transrectal ultrasound-B-mode US (BMUS), power Doppler (PDUS), and sonographic contrast (CEUS) in early imaging-based diagnosis of localized prostate cancer (PCa) and to compare the diagnostic profitability of randomized biopsy (RB), US-targeted prostate biopsy by means of PDUS and CEUS. A single-center, prospective, transversal, epidemiological study was conducted from January 2010 to January 2014. We consecutively included patients who an imaging study of the prostate with BMUS, PDUS, and CEUS was performed, followed by prostate biopsy due to clinical suspicion of prostate cancer (PSA 4-20ng/mL and/or rectal exam suggestive of malignancy). The diagnostic performance of BMUS, PDUS, and CEUS was determined by calculating the Sensitivity (S), Specificity (Sp), Predictive values (PV), and diagnostic odds ratio (OR) of the diagnosis tests and, for these variables, in the population general and based on their clinical stage according to rectal exam (cT1 and cT2). PCa detection rates determined by means of a randomized 10-core biopsy scheme were compared with detection rates of CEUS-targeted (SonoVue) 2-core biopsies. Of the initial 984 patients, US contrast SonoVue was administered to 179 (18.2%). The PCa detection rate by organ of BMUS/PDUS in the global population was 38% versus 43% in the subpopulation with CEUS. The mean age of the patients was 64.3±7.01years (95% CI, 63.75-64.70); mean total PSA was 8.9±3.61ng/mL (95% CI, 8.67-9.13) and the mean prostate volume was 56.2±29cc (95% CI, 54.2-58.1). The detection rate by organ of targeted biopsy with BMUS, PDUS, and CEUS were as follows: Global population (10.6, 8.2, 24.5%), stage cT1 (5.6, 4.2, 16.4%), and stage cT2 (32.4, 22.3, 43.5%). Comparing the detection rates of the CEUS-targeted biopsy and randomized biopsy, the following results were obtained: Global population (24.5% vs. 41.8%), stage cT1 (16% vs. 35%), and stage cT2 (43.5% vs. 66.6%), with a p value0

  11. Strategic plan for the development of core technologies for the Korean advanced nuclear power reactor for export

    International Nuclear Information System (INIS)

    Moon, Joo Hyun; Cho, Young Ho

    2010-01-01

    With the soaring oil price and worsening global warming, nuclear power has attracted considerable attention on a global scale and a new large market of nuclear power plants (NPPs) is expected. The Korean government aims to export up to 10 NPPs by 2012, based on the successful export of 2 NPPs to the UAE in 2009. It is also going to develop a follow-up model of the Advanced Power Reactor (APR) 1400, and join the world's NPP market under the banner of Korea's original reactor type. For this, it promulgated the strategic plan, NuTech 2012, a technology development plan intended for the early acquisition of core technologies for the Korean advanced NPP design and domestic production of the main components in NPP. This paper introduces the strategic plan of NuTech 2012. (orig.)

  12. Diagnostics for the National Compact Stellarator Experiment

    International Nuclear Information System (INIS)

    Stratton, B.C.; Johnson, D.; Feder, R.; Fredrickson, E.; Neilson, H.; Takahashi, H.; Zarnstorf, M.; Cole, M.; Goranson, P.; Lazarus, E.; Nelson, B.

    2003-01-01

    The status of planning of the National Compact Stellarator Experiment (NCSX) diagnostics is presented, with the emphasis on resolution of diagnostics access issues and on diagnostics required for the early phases of operation

  13. The ITER bolometer diagnostic: Status and plansa)

    Science.gov (United States)

    Meister, H.; Giannone, L.; Horton, L. D.; Raupp, G.; Zeidner, W.; Grunda, G.; Kalvin, S.; Fischer, U.; Serikov, A.; Stickel, S.; Reichle, R.

    2008-10-01

    A consortium consisting of four EURATOM Associations has been set up to develop the project plan for the full development of the ITER bolometer diagnostic and to continue urgent R&D activities. An overview of the current status is given, including detector development, line-of-sight optimization, performance analysis as well as the design of the diagnostic components and their integration in ITER. This is complemented by the presentation of plans for future activities required to successfully implement the bolometer diagnostic, ranging from the detector development over diagnostic design and prototype testing to RH tools for calibration.

  14. Diagnostic system for primary circuits of pressurized-water reactors

    International Nuclear Information System (INIS)

    Liska, J.; Majer, J.

    1983-01-01

    The diagnostic system monitors the reactor, the main circulating pipe, the main circulating pump, the main shut-off valve, the steam generator and the pressurizer. Diagnostic signals are obtained from the sensors designed for operation measurements and from sensors for special diagnostic purposes. The following operations are carried out: detection of dangerous dynamic stress of components, detection of damage to functional surfaces of components, detection of occurrence and propagation of defects in component materials, detection of loose particles and foreign bodies, detection of coolant leakage, detection of coolant boiling in the core and detection of impermissible non-homogeneities of fields of physical quantities in the core. The diagnostic system comprises: monitoring, classification of properly investigated effects, periodical tracing and long-term tracing. The operational diagnostics system developed by the SKODA Concern consists of a vibration monitoring system, a spectral analysis system and a central evaluation system. (M.D.)

  15. MFTF-B plasma-diagnostic system

    International Nuclear Information System (INIS)

    Throop, A.L.; Goerz, D.A.; Thomas, S.R.

    1981-01-01

    This paper describes the current design status of the plasma diagnostic system for MFTF-B. In this paper we describe the system requirement changes which have occurred as a result of the funded rescoping of the original MFTF facility into MFTF-B. We outline the diagnostic instruments which are currently planned, and present an overview of the diagnostic system

  16. Evidence-based development of a diagnosis-dependent therapy planning system and its implementation in modern diagnostic software.

    Science.gov (United States)

    Ahlers, M O; Jakstat, H A

    2005-07-01

    The prerequisite for structured individual therapy of craniomandibular dysfunctions is differential diagnostics. Suggestions for the structured recording of findings and their structured evaluation beyond the global diagnosis of "craniomandibular disorders" have been published. Only this structured approach enables computerization of the diagnostic process. The respective software is available for use in practice (CMDcheck for CMD screening, CMDfact for the differential diagnostics). Based on this structured diagnostics, knowledge-based therapy planning is also conceivable. The prerequisite for this would be a model of achieving consensus on the indicated forms of therapy related to the diagnosis. Therefore, a procedure for evidence-based achievement of consensus on suitable forms of therapy in CMD was developed first in multicentric cooperation, and then implemented in corresponding software. The clinical knowledge of experienced specialists was included consciously for the consensus achievement process. At the same time, anonymized mathematical statistical evaluations were used for control and objectification. Different examiners form different departments of several universities working independently of one another assigned the theoretically conceiveable therapeutic alternatives to the already published diagnostic scheme. After anonymization, the correlation of these assignments was then calculated mathematically. For achieving consensus in those cases for which no agreement initally existed, agreement was subsequently arrived at in the course of a consensus conference on the basis of literature evaluations and the discussion of clinical case examples. This consensus in turn finally served as the basis of a therapy planner implemented in the above-mentioned diagnostic software CMDfact. Contributing to quality assurance, the principles of programming this assistant as well as the interface for linking into the diagnostic software are documented and also published

  17. Diagnostic accuracy of semi-automatic quantitative metrics as an alternative to expert reading of CT myocardial perfusion in the CORE320 study.

    Science.gov (United States)

    Ostovaneh, Mohammad R; Vavere, Andrea L; Mehra, Vishal C; Kofoed, Klaus F; Matheson, Matthew B; Arbab-Zadeh, Armin; Fujisawa, Yasuko; Schuijf, Joanne D; Rochitte, Carlos E; Scholte, Arthur J; Kitagawa, Kakuya; Dewey, Marc; Cox, Christopher; DiCarli, Marcelo F; George, Richard T; Lima, Joao A C

    2018-04-03

    To determine the diagnostic accuracy of semi-automatic quantitative metrics compared to expert reading for interpretation of computed tomography perfusion (CTP) imaging. The CORE320 multicenter diagnostic accuracy clinical study enrolled patients between 45 and 85 years of age who were clinically referred for invasive coronary angiography (ICA). Computed tomography angiography (CTA), CTP, single photon emission computed tomography (SPECT), and ICA images were interpreted manually in blinded core laboratories by two experienced readers. Additionally, eight quantitative CTP metrics as continuous values were computed semi-automatically from myocardial and blood attenuation and were combined using logistic regression to derive a final quantitative CTP metric score. For the reference standard, hemodynamically significant coronary artery disease (CAD) was defined as a quantitative ICA stenosis of 50% or greater and a corresponding perfusion defect by SPECT. Diagnostic accuracy was determined by area under the receiver operating characteristic curve (AUC). Of the total 377 included patients, 66% were male, median age was 62 (IQR: 56, 68) years, and 27% had prior myocardial infarction. In patient based analysis, the AUC (95% CI) for combined CTA-CTP expert reading and combined CTA-CTP semi-automatic quantitative metrics was 0.87(0.84-0.91) and 0.86 (0.83-0.9), respectively. In vessel based analyses the AUC's were 0.85 (0.82-0.88) and 0.84 (0.81-0.87), respectively. No significant difference in AUC was found between combined CTA-CTP expert reading and CTA-CTP semi-automatic quantitative metrics in patient based or vessel based analyses(p > 0.05 for all). Combined CTA-CTP semi-automatic quantitative metrics is as accurate as CTA-CTP expert reading to detect hemodynamically significant CAD. Copyright © 2018 Society of Cardiovascular Computed Tomography. Published by Elsevier Inc. All rights reserved.

  18. MTX [Microwave Tokamak Experiment] plasma diagnostic system

    International Nuclear Information System (INIS)

    Rice, B.W.; Hooper, E.B.; Brooksby, C.A.

    1987-01-01

    In this paper, a general overview of the MTX plasma diagnostics system is given. This includes a description of the MTX machine configuration and the overall facility layout. The data acquisition system and techniques for diagnostic signal transmission are also discussed. In addition, the diagnostic instruments planned for both an initial ohmic-heating set and a second FEL-heating set are described. The expected range of plasma parameters along with the planned plasma measurements will be reviewed. 7 refs., 5 figs

  19. Windscale pile core surveys

    International Nuclear Information System (INIS)

    Curtis, R.F.; Mathews, R.F.

    1996-01-01

    The two Windscale Piles were closed down, defueled as far as possible and mothballed for thirty years following a fire in the core of Pile 1 in 1957 resulting from the spontaneous release of stored Wigner energy in the graphite moderator. Decommissioning of the reactors commenced in 1987 and has reached the stage where the condition of both cores needs to be determined. To this end, non-intrusive and intrusive surveys and sampling of the cores have been planned and partly implemented. The objectives for each Pile differ slightly. The location and quantity of fuel remaining in the damaged core of Pile 1 needed to be established, whereas the removal of all fuel from Pile 2 needed to be confirmed. In Pile 1, the possible existence of a void in the core is to be explored and in Pile 2, the level of Wigner energy remaining required to be quantified. Levels of radioactivity in both cores needed to be measured. The planning of the surveys is described including strategy, design, safety case preparation and the remote handling and viewing equipment required to carry out the inspection, sampling and monitoring work. The results from the completed non-intrusive survey of Pile 2 are summarised. They confirm that the core is empty and the graphite is in good condition. The survey of Pile 1 has just started. (UK)

  20. Intersection planning in Safer Transportation Network Planning : safety principles, planning framework, and library information.

    NARCIS (Netherlands)

    Hummel, T.

    2001-01-01

    This report is one in a series of publications, used in the development of the network planning tool ‘Safer Transportation Network Planning’ (Safer-TNP). The publications were used to guide the development of planning structures, diagnostic tools, planning recommendations, and research information

  1. Edge diagnostics for tandem mirror machines

    International Nuclear Information System (INIS)

    Allen, S.L.

    1984-01-01

    The edge plasma in a tandem mirror machine shields the plasma core from cold neutral gas and impurities. A variety of diagnostics are used to measure the fueling, shielding, and confinement of the edge plasma in both the end plug and central cell regions. Fast ion gauges and residual gas analyzers measure the gas pressure and composition outside of the plasma. An array of Langmuir probes is used to measure the electron density and temperature. Extreme ultraviolet (euv) and visible spectroscopy are used to measure both the impurity and deuterium densities and to estimate the shielding factor for the core plasma. The linear geometry of a tandem mirror also allows direct measurements of the edge plasma by sampling the ions and electrons lost but the ends of the machine. Representative data obtained by these diagnostics during operation of the Tandem Mirror Experiment (TMX) and Tandem Mirror Experiment-Upgrade (TMX-U) experiments are presented. Diagnostics that are currently being developed to diagnose the edge plasma are also discussed

  2. National NIF Diagnostic Program Fiscal Year 2002 Second Quarter Report

    International Nuclear Information System (INIS)

    MacGowan, B

    2002-01-01

    Since October 2001 the development of the facility diagnostics for NIF has been funded by the NIF Director through the National NIF Diagnostic Program (NNDP). The current emphasis of the NNDP is on diagnostics for the early NIF quad scheduled to be available for experiment commissioning in FY03. During the past six months the NNDP has set in place processes for funding diagnostics, developing requirements for diagnostics, design reviews and monthly status reporting. Those processes are described in an interim management plan for diagnostics (National NIF Diagnostic Program Interim Plan, NIF-008 13 15, April 2002) and a draft Program Execution Plan (Program Execution Plan for the National NlF Diagnostic Program, NIF-0072083, October 2001) and documents cited therein. Work has been funded at Lawrence Livermore National Laboratory (LLNL), Los Alamos National Laboratory (LANL), Naval Research Laboratory (NRL), Sandia National Laboratories (SNL), Bechtel Nevada at Los Alamos and Santa Barbara. There are no major technical risks with the early diagnostics. The main concerns relate to integration of the diagnostics into the facility, all such issues are being worked. This report is organized to show the schedule and budget status and a summary of Change Control Board actions for the past six months. The following sections then provide short descriptions of the status of each diagnostic. Where design reviews or requirements documents are cited, the documents are available on the Diagnostics file server or on request

  3. Correlation ECE diagnostic in Alcator C-Mod

    International Nuclear Information System (INIS)

    Sung, C.; Irby, J.; Leccacorvi, R.; Vieira, R.; Oi, C.; Rice, J.; Reinke, M.; Gao, C.; Ennever, P.; Porkolab, M.; Churchill, R.; Theiler, C.; Walk, J.; Hughes, J.; Hubbard, A.; Greenwald, M.

    2015-01-01

    Correlation ECE (CECE) is a diagnostic technique that allows measurement of small amplitude electron temperature, Te, fluctuations through standard cross-correlation analysis methods. In Alcator C-Mod, a new CECE diagnostic has been installed[Sung RSI 2012], and interesting phenomena have been observed in various plasma conditions. We find that local Te fluctuations near the edge (ρ ~ 0:8) decrease across the linearto- saturated ohmic confinement transition, with fluctuations decreasing with increasing plasma density [Sung NF 2013], which occurs simultaneously with rotation reversals [Rice NF 2011]. Te fluctuations are also reduced across core rotation reversals with an increase of plasma density in RF heated L-mode plasmas, which implies that the same physics related to the reduction of Te fluctuations may be applied to both ohmic and RF heated L-mode plasmas. In I-mode plasmas, we observe the reduction of core Te fluctuations, which indicates changes of turbulence occur not only in the pedestal region but also in the core across the L/I transition [White NF 2014]. The present CECE diagnostic system in C-Mod and these experimental results are described in this paper

  4. Land use planning in Safer Transportation Network Planning : safety principles, planning framework, and library information.

    NARCIS (Netherlands)

    Hummel, T.

    2001-01-01

    This report is one in a series of publications, used in the development of the network planning tool ‘Safer Transportation Network Planning’ (Safer-TNP). The publications were used to guide the development of planning structures, diagnostic tools, planning recommendations, and research information

  5. Physics measurements on WWER-440 diagnostic assemblies

    International Nuclear Information System (INIS)

    Dach, K.; Jirousek, V.; Kott, J.; Horak, J.; Teren, S.; Nemec, J.

    1980-01-01

    The aims of physics measurements using diagnostic assemblies are the development of neutron noise diagnostics methods, the improvement of knowledge of the physical properties of the WWER reactor cores, the testing of computer programs, and the specification of nuclear safety criteria and the obtaining of information allowing the optimum nuclear fuel economy. The instrumentation of diagnostic assemblies is briefly described, including miniature fission chambers, SPN detectors and calorimeters. The method of evaluating and experimental testing is shown. (M.S.)

  6. The ICF National Diagnostic Plan (NDP) 9/19/17

    Energy Technology Data Exchange (ETDEWEB)

    Kilkenny, J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Richau, G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Sangster, C. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Batha, S. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Bell, P. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Larson, D. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Bradley, D. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Leeper, R. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Herrmann, H. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Bourdon, C. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Hilsabeck, T. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2017-10-02

    A major goal of the Stockpile Stewardship Program (SSP) is to deliver validated numerical models, benchmarked against experiments that address relevant and important issues and provide data that stress the codes and our understanding. DOENNSA has made significant investments in major facilities and high-performance computing to successfully execute the SSP. The more information obtained about the physical state of the plasmas produced, the more stringent the test of theories, models, and codes can be, leading to increased confidence in our predictive capability. To fully exploit the world-leading capabilities of the ICF program, a multi-year program to develop and deploy advanced diagnostics has been developed by the expert scientific community. To formalize these activities NNSA’s Acting Director for the Inertial Confinement Fusion Program directed the formation and duties of the National Diagnostics Working Group (NDWG) in a Memorandum 11/3/16 (Appendix A). The NDWG identified eight transformational diagnostics, shown in Table 1, that will provide unprecedented information from experiments in support of the SSP at NIF, Z and OMEGA. Table 1 shows how the missions of the SSP experiments including materials, complex hydrodynamics, radiation flow and effects and thermo-nuclear burn and boost will produce new observables, which will be measured using a variety of largely new diagnostic technologies used in the eight transformational diagnostics. The data provided by these diagnostics will validate and improve the physics contained within the SSP’s simulations and both uncover and quantify important phenomena that lie beyond our present understanding.

  7. CT Fluoroscopy-Guided Core Biopsy for Diagnosis of Small ({<=} 20 mm) Pulmonary Nodules

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Hye Larn; Kim, Yoon Kyung; Woo, Ok Hee; Yong, Hwan Seok; Kang, Eun Young [Dept. of Radiology, Korea University Guro Hospital, Korea University College of Medicine, Seoul (Korea, Republic of); Kim, Hyun Koo [Dept. of Thoracic Surgery, Korea University Guro Hospital, Korea University College of Medicine, Seoul (Korea, Republic of); Shin, Bong Kyung [Dept. of Pathology, Korea University Guro Hospital, Korea University College of Medicine, Seoul (Korea, Republic of)

    2011-10-15

    To evaluate the efficacy of CT fluoroscopy-guided core biopsy of small pulmonary nodules. This study included 62 patients (35 men, 27 women; age range, 36-85 years) that had a small ({<=} 20 mm) pulmonary nodule and underwent CT fluoroscopy-guided core biopsy. The overall diagnostic accuracy and complication rate were calculated. The diagnostic accuracy was compared between two groups according to the nodule size ({<=} 10 mm vs. > 10 mm), and nodule density (solid vs. subsolid). Malignant or premalignant lesions were finally diagnosed in 39 patients; 36 true-positive and three false-negative findings (sensitivity, 92%). A benign lesion was finally diagnosed in 23 patients, with no false-positive results (specificity, 100%). The overall diagnostic accuracy was 95%. The sensitivity and diagnostic accuracy were 85% and 91% for nodules {<=} 10 mm, and 96% and 97% for nodules > 10 mm (p > 0.05). The sensitivity and diagnostic accuracy were 93% and 96% in the solid group and 90% and 92% in the subsolid group (p > 0.05). Seventeen (27%) patients had a pneumothorax and two (3%) required a closed thoracostomy. CT fluoroscopy-guided core biopsy of small pulmonary nodules yields high diagnostic accuracy with acceptable complication rates.

  8. Study of the mechanism of clamping and detachment of a core sample by core lever lifters

    Energy Technology Data Exchange (ETDEWEB)

    Barabashkin, I I; Mizyakin, V M; Nikitin, S V

    1981-01-01

    Geometric dimensions of the basic elements of a core lifter should be determined depending on the clamping conditions. The changes should be determined depending on the conditions of the core sample diameter, critical angle between the lever and the core samples in the necessary depth of submersion of the contact edge of the lever into its surface. The core lifter KTsRZ-80 with eccentric core reception makes it possible to arrange more efficiently the core removing elements on the edge of the band. The use of the core lifters with eccentric plan of arrangement of the levers and their optimal length increases the removal of the core sample.

  9. Proceeding of JSPS-CAS core university program seminar on production and control of high performance plasmas with advanced plasma heating and diagnostic systems

    International Nuclear Information System (INIS)

    Gao Xiang; Morita, Shigeru

    2009-01-01

    The JSPS-CAS Core University Program (CUP) seminar on 'Production and control of high performance plasmas with advanced plasma heating and diagnostic systems' took place in Shiner hotel, Lijiang, China, 4-7 November 2008. This seminar was organized in the framework of CUP in the field of plasma and nuclear fusion. One special talk and 34 oral talks were presented in the seminar including 16 Japanese attendees. Production and control of high performance plasmas is a crucial issue for realizing an advanced nuclear fusion reactor in addition to developments of advanced plasma heating and diagnostics. This seminar was motivated along the issues. Results obtained from CUP activities during recent four years were summarized. Several crucial issues to be resolved near future were also extracted in this seminar. The 31 of the papers are indexed individually. (J.P.N.)

  10. Tank 241-SY-101 push mode core sampling and analysis plan

    International Nuclear Information System (INIS)

    CONNER, J.M.

    1998-01-01

    This sampling and analysis plan (SAP) identifies characterization objectives pertaining to sample collection, laboratory analytical evaluation, and reporting requirements for push mode core samples from tank 241-SY-101 (SY-101). It is written in accordance with Data Quality Objective to Support Resolution of the Flammable Gas Safety Issue (Bauer 1998), Low Activity Waste Feed Data Quality Objectives (Wiemers and Miller 1997 and DOE 1998), Data Quality Objectives for TWRS Privatization Phase I: Confirm Tank T is an Appropriate Feed Source for Low-Activity Waste Feed Batch X (Certa 1998), and the Tank Safety Screening Data Quality Objective (Dukelow et al. 1995). The Tank Characterization Technical Sampling Basis document (Brown et al. 1998) indicates that these issues apply to tank SY-101 for this sampling event. Brown et al. also identifies high-level waste, regulatory, pretreatment and disposal issues as applicable issues for this tank. However, these issues will not be addressed via this sampling event

  11. Expression of Hepatitis C Virus Core and E2 antigenic recombinant proteins and their use for development of diagnostic assays.

    Science.gov (United States)

    Ali, Amjad; Nisar, Muhammad; Idrees, Muhammad; Rafique, Shazia; Iqbal, Muhammad

    2015-05-01

    Early diagnosis of HCV infection is based on detection of antibodies against HCV proteins using recombinant viral antigens. The present study was designed to select, clone and express the antigenic regions of Core and E2 genes from local HCV-3a genotype and to utilize the antigenic recombinant proteins (Core & E2) to develop highly sensitive, specific and economical diagnostic assays for detection of HCV infection. The antigenic sites were determined within Core and E2 genes and were then cloned in pET-28a expression vector. The right orientation of the desired inserted fragments of Core and E2 were confirmed via sequencing prior to expression and were then transformed in BL21 (DE3) pLysS strains of E. coli and induced with 0.5mM Isopropyl-b-D-thiogalactopyranoside (IPTG) for the production of antigenic recombinant proteins. The produced truncated antigens were then purified by Nickel affinity chromatography and were confirmed by western blotting, immunoblotting and enzyme-linked immunosorbent assay (ELISA). The expressed Core and E2 recombinant antigens were used to develop immunoblotting assay for the detection of anti-HCV antibodies in sera. With immunoblotting, a total of 93-HCV infected sera and 35-HCV negative individuals were tested for the presence of anti-HCV antibodies to the Core and E2 antigens. Recombinant antigen showed 100% reactivity against HCV infected sera, with no cross reactivity against HCV-negative sera. The immunoblot assay mixture of recombinant antigens (Core+E2) showed a strong reaction intensity in the test area (TA) as compared to the individual truncated Core and E2 recombinant antigens. In the in-house ELISA assay, mixed Core and E2 recombinant antigens showed 100% reactivity against a standardized panel of 150-HCV-positive sera and non reactivity against a standardized panel of 150 HCV-negative sera while also being non reactive to sera positive for other viral infections. The antigenic recombinant antigens also were tested for the

  12. Functional MRI in schizophrenia. Diagnostics and therapy monitoring of cognitive deficits of schizophrenic patients by functional MRI

    International Nuclear Information System (INIS)

    Furtner, J.; Prayer, D.; Sachs, G.

    2010-01-01

    Cognitive impairments are core psychopathological components of the symptomatic of schizophrenic patients. These dysfunctions are generally related to attention, executive functions and memory. This report provides information on the importance of using functional magnetic resonance imaging (fMRI) for the diagnostics and therapy monitoring of the different subtypes of cognitive dysfunctions. Furthermore, it describes the typical differences in the activation of individual brain regions between schizophrenic patients and healthy control persons. This information should be helpful in identifying the deficit profile of each patient and create an individual therapy plan. (orig.) [de

  13. Companion diagnostics: a regulatory perspective from the last 5 years of molecular companion diagnostic approvals.

    Science.gov (United States)

    Roscoe, Donna M; Hu, Yun-Fu; Philip, Reena

    2015-01-01

    Companion diagnostics are essential for the safe and effective use of the corresponding therapeutic products. The US FDA has approved a number of companion diagnostics used to select cancer patients for treatment with contemporaneously approved novel therapeutics. The processes of co-development and co-approval of a therapeutic product and its companion diagnostic have been a learning experience that continues to evolve. Using several companion diagnostics as examples, this article describes the challenges associated with the scientific, clinical and regulatory hurdles faced by FDA and industry alike. Taken together, this discussion is intended to assist manufacturers toward a successful companion diagnostics development plan.

  14. Calibration issues for neutron diagnostics

    International Nuclear Information System (INIS)

    Sadler, G.J.; Adams, J.M.; Barnes, C.W.

    1997-10-01

    In order for ITER to meet its operational and programmatic goals, it will be necessary to measure a wide range of plasma parameters. Some of the required parameters e.g., neutron yield, fusion power and power density, ion temperature profile in the core plasma, and characteristics of confined and escaping alpha particle populations are best measured by fusion product diagnostic techniques. To make these measurements, ITER will have dedicated diagnostic systems, including radial and vertical neutron cameras, neutron and gamma ray spectrometers, internal and external fission chambers, a neutron activation system, and diagnostics for confined and escaping alpha particles. Engineering integration of many of these systems is in progress, and other systems are under investigation. This paper summarizes the present state of design of fusion product diagnostic systems for ITER and discusses expected measurement capability

  15. Core Muscle Injury/Sports Hernia/Athletic Pubalgia, and Femoroacetabular Impingement.

    Science.gov (United States)

    Ross, James R; Stone, Rebecca M; Larson, Christopher M

    2015-12-01

    Core muscle injury/sports hernia/athletic pubalgia is an increasingly recognized source of pain, disability, and time lost from athletics. Groin pain among athletes, however, may be secondary to various etiologies. A thorough history and comprehensive physical examination, coupled with appropriate diagnostic imaging, may improve the diagnostic accuracy for patients who present with core muscular injuries. Outcomes of nonoperative management have not been well delineated, and multiple operative procedures have been discussed with varying return-to-athletic activity rates. In this review, we outline the clinical entity and treatment of core muscle injury and athletic pubalgia. In addition, we describe the relationship between athletic pubalgia and femoroacetabular impingement along with recent studies that have investigated the treatment of these related disorders.

  16. Performance, diagnostics, controls and plans for the gyrotron system on the DIII-D tokamak

    Directory of Open Access Journals (Sweden)

    Ponce D.M.

    2012-09-01

    Full Text Available The DIII-D ECH complex is being upgraded with three new depressed collector gyrotrons. The performance of the existing system has been very good. As more gyrotrons having higher power are added to the system, diagnostics of gyrotron operation, optimization of the performance and qualification of components for higher power become more important. A new FPGA-based gyrotron control system is being installed, additional capabilities for rapid real time variation of the rf injection angles by the DIII-D Plasma Control System are being tested and infrastructure enhancements are being completed. Longer term plans continue to include ECH as a major component in the DIII-D heating and current drive capabilities.

  17. Comment on the in-core measurement in the WWER nuclear power plant

    International Nuclear Information System (INIS)

    Krett, V.; Dach, K.; Erben, O.

    1985-01-01

    The activity of the Nuclear Research Institute (NRI) Rez in the field of in-core measurement sensors is described in the paper. The results of comparison and calibration experiments realized on the WWR-S research reactor at the NRI are presented. Measurements with fission calorimeters and SPN detectors carried out in the framework of diagnostic fuel assembly program of WWER NPP reactors are described. Noise measurements with detectors of in-core instrumentation of diagnostic fuel assemblies are also mentioned. Comparison experiments on the WWER-440 NPP reactor are described and the method of function verification of neutron sensors of the in-core control system of these reactors is given. (author)

  18. ARM Data-Oriented Metrics and Diagnostics Package for Climate Model Evaluation Value-Added Product

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Chengzhu [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Xie, Shaocheng [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2017-10-15

    A Python-based metrics and diagnostics package is currently being developed by the U.S. Department of Energy (DOE) Atmospheric Radiation Measurement (ARM) Infrastructure Team at Lawrence Livermore National Laboratory (LLNL) to facilitate the use of long-term, high-frequency measurements from the ARM Facility in evaluating the regional climate simulation of clouds, radiation, and precipitation. This metrics and diagnostics package computes climatological means of targeted climate model simulation and generates tables and plots for comparing the model simulation with ARM observational data. The Coupled Model Intercomparison Project (CMIP) model data sets are also included in the package to enable model intercomparison as demonstrated in Zhang et al. (2017). The mean of the CMIP model can serve as a reference for individual models. Basic performance metrics are computed to measure the accuracy of mean state and variability of climate models. The evaluated physical quantities include cloud fraction, temperature, relative humidity, cloud liquid water path, total column water vapor, precipitation, sensible and latent heat fluxes, and radiative fluxes, with plan to extend to more fields, such as aerosol and microphysics properties. Process-oriented diagnostics focusing on individual cloud- and precipitation-related phenomena are also being developed for the evaluation and development of specific model physical parameterizations. The version 1.0 package is designed based on data collected at ARM’s Southern Great Plains (SGP) Research Facility, with the plan to extend to other ARM sites. The metrics and diagnostics package is currently built upon standard Python libraries and additional Python packages developed by DOE (such as CDMS and CDAT). The ARM metrics and diagnostic package is available publicly with the hope that it can serve as an easy entry point for climate modelers to compare their models with ARM data. In this report, we first present the input data, which

  19. Current status of core needle biopsy of the thyroid

    Energy Technology Data Exchange (ETDEWEB)

    Baek, Jung Hwan [Dept. of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul (Korea, Republic of)

    2017-04-15

    Thyroid nodules are a common clinical problem. Fine-needle aspiration (FNA) and large-needle biopsy have been used to diagnose thyroid nodules. Before the 1980s, large-needle biopsy was the standard procedure for the thyroid, but FNA became the standard diagnostic tool in the 1980s because it is a safe procedure that leads to accurate diagnoses. With advances in core needle biopsy (CNB) devices (i.e., spring-activated core needles) and development of high-resolution ultrasound, it has become possible to make accurate diagnoses while minimizing complications. Although 18- to 21-gauge core needles can be used to biopsy thyroid nodules, 18-gauge needles are most commonly used in Korea. The relationships among the size of the needle, the number of core specimens, and diagnostic accuracy have not yet been conclusively established, but the general tendency is that thinner needles cause less damage to the normal thyroid, but allow a smaller amount of thyroid tissue to be biopsied to be obtained. These relationships may be validated in the future.

  20. Commissioning plans for SSC linac

    International Nuclear Information System (INIS)

    Hurd, J.W.; Aprile, R.L.; Chang, C.R.; Crist, C.E.; Cutler, R.I.; Funk, L.W.; Guy, F.W.; Leifeste, G.T.; Raparia, D.; Saadatmand, K.; Sethi, R.C.; Swenson, D.A.; Tooker, J.; Yao, C.G.

    1992-01-01

    Presented are the general description of the SSC linac and the plans for commissioning. Sections of the linac are installed, tested, and beam commissioned in a serial approach. A specialized set of diagnostics is used to characterize the beam through each section. In addition to the standard diagnostic set, plans call for the use of a bunch shape monitor and x-ray spectrometer. Streak camera and digital imaging diagnostics will be developed. The commissioning plan is folded into the general linac project schedule to show the relation between delivery, staging, installation, conditioning, and actual commissioning with beam. These plans form the basis for coordination between the various organizations responsible for different elements of the linac including the technical components, infrastructure, and temporary staging and operation facilities. (Author) 2 figs., 17 refs

  1. EPOS Thematic Core Service Anthropogenic Hazards: Implementation Plan

    Science.gov (United States)

    Orlecka-Sikora, Beata; Lasocki, Stanislaw; Grasso, Jean Robert; Schmittbuhl, Jean; Styles, Peter; Kwiatek, Grzegorz; Sterzel, Mariusz; Garcia, Alexander

    2015-04-01

    EPOS Thematic Core Service ANTHROPOGENIC HAZARDS (TCS AH) aims to integrate distributed research infrastructures (RI) to facilitate and stimulate research on anthropogenic hazards (AH) especially those associated with the exploration and exploitation of geo-resources. The innovative element is the uniqueness of the integrated RI which comprises two main deliverables: (1) Exceptional datasets, called "episodes", which comprehensively describe a geophysical process; induced or triggered by human technological activity, posing hazard for populations, infrastructure and the environment, (2) Problem-oriented, bespoke services uniquely designed for the discrimination and analysis of correlations between technology, geophysical response and resulting hazard. These objectives will be achieved through the Science-Industry Synergy (SIS) built by EPOS WG10, ensuring bi-directional information exchange, including unique and previously unavailable data furnished by industrial partners. The Episodes and services to be integrated have been selected using strict criteria during the EPOS PP. The data are related to a wide spectrum of inducing technologies, with seismic/aseismic deformation and production history as a minimum data set requirement and the quality of software services is confirmed and referenced in literature. Implementation of TCS AH is planned for four years and requires five major activities: (1) Strategic Activities and Governance: will define and establish the governance structure to ensure the long-term sustainability of these research infrastructures for data provision through EPOS. (2) Coordination and Interaction with the Community: will establish robust communication channels within the whole TCS AH community while supporting global EPOS communication strategy. (3) Interoperability with EPOS Integrated Core Service (ICS) and Testing Activities: will coordinate and ensure interoperability between the RIs and the ICS. Within this modality a functional e

  2. Wavelet and Spectral Analysis of Some Selected Problems in Reactor Diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Sunde, Carl

    2004-12-01

    Both spectral and wavelet analysis were successfully used in various diagnostic problems involving non-stationary core processes in nuclear power reactors. Three different problems were treated: two-phase flow identification, detector tube impacting and core-barrel vibrations. The first two problems are of non-stationary nature, whereas the last one is not. In the first problem, neutron radiographic and visible light images of four different vertical two-phase flow regimes, bubbly, slug, chum and annular flow, were analysed and classified with a neuro-wavelet algorithm. The algorithm consists of a wavelet part, using the 2-D discrete wavelet transform and of an artificial neural network. It classifies the different flow regimes with up to 99% efficiency. Detector tubes in a Boiling Water Reactor may execute vibrations and may also impact on nearby fuel-assemblies. Signals from in-core neutron detectors in Ringhals-1 were analysed, for detection of impacting, with both a classical spectral method and wavelet-based methods. The wavelet methods include both the discrete and the continuous 1-D wavelet transform. It was found that there is agreement between the different methods as well as with visual inspections made during the outage at the plant. However, the wavelet technique has the advantage that it does not require expert judgement for the interpretation of the analysis. In the last part two analytical calculations of the neutron noise, induced by shell-mode core-barrel vibrations, were carried out. The results are in good agreement with calculations from a numerical simulator. An out-of-phase behaviour between in-core and ex-core positions was found, which is in agreement with earlier measurements from the Pressurised Water Reactor Ringhals-3. The results from these calculations are planned to be used when diagnosing the shell-mode core-barrel vibrations in an operating plant.

  3. Wavelet and Spectral Analysis of Some Selected Problems in Reactor Diagnostics

    International Nuclear Information System (INIS)

    Sunde, Carl

    2004-12-01

    Both spectral and wavelet analysis were successfully used in various diagnostic problems involving non-stationary core processes in nuclear power reactors. Three different problems were treated: two-phase flow identification, detector tube impacting and core-barrel vibrations. The first two problems are of non-stationary nature, whereas the last one is not. In the first problem, neutron radiographic and visible light images of four different vertical two-phase flow regimes, bubbly, slug, chum and annular flow, were analysed and classified with a neuro-wavelet algorithm. The algorithm consists of a wavelet part, using the 2-D discrete wavelet transform and of an artificial neural network. It classifies the different flow regimes with up to 99% efficiency. Detector tubes in a Boiling Water Reactor may execute vibrations and may also impact on nearby fuel-assemblies. Signals from in-core neutron detectors in Ringhals-1 were analysed, for detection of impacting, with both a classical spectral method and wavelet-based methods. The wavelet methods include both the discrete and the continuous 1-D wavelet transform. It was found that there is agreement between the different methods as well as with visual inspections made during the outage at the plant. However, the wavelet technique has the advantage that it does not require expert judgement for the interpretation of the analysis. In the last part two analytical calculations of the neutron noise, induced by shell-mode core-barrel vibrations, were carried out. The results are in good agreement with calculations from a numerical simulator. An out-of-phase behaviour between in-core and ex-core positions was found, which is in agreement with earlier measurements from the Pressurised Water Reactor Ringhals-3. The results from these calculations are planned to be used when diagnosing the shell-mode core-barrel vibrations in an operating plant

  4. Diagnostic Imaging Workshop

    International Nuclear Information System (INIS)

    Sociedad Argentina de Fisica Medica

    2012-01-01

    The American Association of Physicist in Medicine (AAPM), the International Organization for Medical Physics (IOMP) and the Argentina Society of Medical Physics (SAFIM) was organized the Diagnostic Imaging Workshop 2012, in the city of Buenos Aires, Argentina. This workshop was an oriented training and scientific exchange between professionals and technicians who work in medical physics, especially in the areas of diagnostic imaging, nuclear medicine and radiotherapy, with special emphasis on the use of multimodal imaging for radiation treatment, planning as well of quality assurance associates.

  5. Enhanced NIF neutron activation diagnostics.

    Science.gov (United States)

    Yeamans, C B; Bleuel, D L; Bernstein, L A

    2012-10-01

    The NIF neutron activation diagnostic suite relies on removable activation samples, leading to operational inefficiencies and a fundamental lower limit on the half-life of the activated product that can be observed. A neutron diagnostic system measuring activation of permanently installed samples could remove these limitations and significantly enhance overall neutron diagnostic capabilities. The physics and engineering aspects of two proposed systems are considered: one measuring the (89)Zr/(89 m)Zr isomer ratio in the existing Zr activation medium and the other using potassium zirconate as the activation medium. Both proposed systems could improve the signal-to-noise ratio of the current system by at least a factor of 5 and would allow independent measurement of fusion core velocity and fuel areal density.

  6. Expert system for fast reactor diagnostic

    International Nuclear Information System (INIS)

    Parcy, J.P.

    1982-09-01

    A general description of expert systems is given. The operation of a fast reactor is reviewed. The expert system to the diagnosis of breakdowns limited to the reactor core. The structure of the system is described: specification of the diagnostics; structure of the data bank and evaluation of the rules; specification of the prediagnostics and evaluation; explanation of the diagnostics; time evolution of the system; comparison with other expert systems. Applications to some cases of faults are finally presented [fr

  7. The diagnostic and therapeutic impact of MRI: an observational multi-centre study

    International Nuclear Information System (INIS)

    Hollingworth, William; Todd, Christopher J.; Bell, Matthew I.; Arafat, Qais; Girling, Simon; Karia, Kanti R.; Dixon, Adrian K.

    2000-01-01

    AIM: To provide information about the diagnostic and therapeutic impact of magnetic resonance imaging (MRI) and to compare the findings across diagnostic groups. MATERIALS AND METHODS: A prospective, observational study of 2017 consecutive referrals for MRI of the head, spine or knee at four imaging centres. Clinicians completed questionnaires before MRI stating initial diagnoses, diagnostic confidence and treatment plans. After imaging, a second questionnaire evaluated clinicians' revised diagnosis and treatment plans in the light of imaging findings. Patients were grouped into nine diagnostic categories for analysis. Comparison between pre- and post-imaging was used to assess the diagnostic and therapeutic impact of MRI. RESULTS: In seven of nine diagnostic groups MRI findings were associated with a diagnostic impact. Diagnoses were revised or discarded following normal MR findings and diagnostic confidence was increased by confirmative MR findings. There was no statistically significant diagnostic impact for suspected pituitary or cerebello-pontine angle lesions. In five of nine diagnostic groups (knee meniscus, knee ligament, multiple sclerosis, lumbar and cervical spine) MRI findings had a clear impact on treatment plans. CONCLUSION: This study demonstrates that in most diagnostic categories, MRI influences diagnosis and treatment. However, experimental studies are needed to prove that these diagnostic and therapeutic impacts lead to improved health. Hollingworth (2000)

  8. The diagnostic and therapeutic impact of MRI: an observational multi-centre study

    Energy Technology Data Exchange (ETDEWEB)

    Hollingworth, William; Todd, Christopher J.; Bell, Matthew I.; Arafat, Qais; Girling, Simon; Karia, Kanti R.; Dixon, Adrian K

    2000-11-01

    AIM: To provide information about the diagnostic and therapeutic impact of magnetic resonance imaging (MRI) and to compare the findings across diagnostic groups. MATERIALS AND METHODS: A prospective, observational study of 2017 consecutive referrals for MRI of the head, spine or knee at four imaging centres. Clinicians completed questionnaires before MRI stating initial diagnoses, diagnostic confidence and treatment plans. After imaging, a second questionnaire evaluated clinicians' revised diagnosis and treatment plans in the light of imaging findings. Patients were grouped into nine diagnostic categories for analysis. Comparison between pre- and post-imaging was used to assess the diagnostic and therapeutic impact of MRI. RESULTS: In seven of nine diagnostic groups MRI findings were associated with a diagnostic impact. Diagnoses were revised or discarded following normal MR findings and diagnostic confidence was increased by confirmative MR findings. There was no statistically significant diagnostic impact for suspected pituitary or cerebello-pontine angle lesions. In five of nine diagnostic groups (knee meniscus, knee ligament, multiple sclerosis, lumbar and cervical spine) MRI findings had a clear impact on treatment plans. CONCLUSION: This study demonstrates that in most diagnostic categories, MRI influences diagnosis and treatment. However, experimental studies are needed to prove that these diagnostic and therapeutic impacts lead to improved health. Hollingworth (2000)

  9. Reduction of vibrational interference from the iron core on HBTXIA

    International Nuclear Information System (INIS)

    Wilcock, P.D.

    1981-01-01

    The HBTXIA machine is a toroidal reversed field pinch which utilises a 1 volt second iron core. This paper looks briefly at the sources of vibration from the iron core and describes the design of a novel support system that has been installed to minimise the transmission of vibration to plasma diagnostics and other equipment during the machine pulse. Vibration measurements on the completed installation when the core is driven to saturation are reported and compared with calculations for a ground mounted core. (author)

  10. Status of TMX upgrade diagnostics construction

    International Nuclear Information System (INIS)

    Hornady, R.S.; Davis, J.C.; Simonen, T.C.

    1981-01-01

    This report describes the status of the initial TMX Upgrade diagnostics and the state of development of additional diagnostics being prepared for later TMX Upgrade experiments. The initial diagnostic instrument set has been described in the TMX Upgrade Proposal. This set is required to get TMX Upgrade operational and to evaluate its initial performance. Additional diagnostic instruments are needed to then carry out the more detailed experiments outlined by the TMX Upgrade program milestones. The relation of these new measurements to the physics program is described in The TMX Upgrade Program Plan

  11. DIAGNOSTICS OF MOTOR ABILITY AS A BASE OF CORRECTION PLANNING OF TRANSFORMATION PROCESSES IN SPECIAL POPULATIONS

    Directory of Open Access Journals (Sweden)

    Kosta Goranović

    2011-08-01

    Full Text Available In the research, at sample of 80 tested, employees in the special police force, as representatives of police population age from 20 to 25, diagnostics of motor potential in transitive period of annual macrostructure was done. The aim of the research was doing potential correction in planning and programming of transformation process in the next cycles of sports preparation on the base of diagnosed quantitative value of motor abilities. Besides analyses of achieved values, the difference was established between two leading teams in the space of measuring potential. The research results indicated to statistically important differences between two groups of tested people, as well as to unacceptable level of development in some abilities. The achieved results are, from aspect of training process’ control, the indicator to instructors’ team on the need of correction of transformation process’ content, with aim of improving bad segments. Diagnostics of motor abilities with measuring instruments in terrain conditions is one of methods, which can be in function of valorising transformation process of the special police force, taking into account specifics of their professional manifestation.

  12. Uncovering student thinking about mathematics in the common core, grades 6-8 25 formative assessment probes

    CERN Document Server

    Tobey, Cheryl Rose

    2013-01-01

    Pinpoint and reverse math misconceptions with laser-like accuracyQuickly and reliably uncover common math misconceptions in Grades 6-8 with these convenient and easy-to-implement diagnostic tools! Bestselling authors Cheryl Tobey and Carolyn Arline provide 25 new assessment probes that pinpoint subconcepts within the new Common Core Standards for Mathematics to promote deep learning and expert math instruction--while learning is already underway.Completely CCSM aligned, these grade-specific probes eliminate the guesswork and help teachers: Systematically address conceptual and procedural mistakes Help students better understand areas of struggle Plan targeted instruction that covers Grades 6-8 CCSM mathematical processes and proficiencies.

  13. Comparison of Histologic Core Portions Acquired from a Core Biopsy Needle and a Conventional Needle in Solid Mass Lesions: A Prospective Randomized Trial.

    Science.gov (United States)

    Lee, Ban Seok; Cho, Chang-Min; Jung, Min Kyu; Jang, Jung Sik; Bae, Han Ik

    2017-07-15

    The superiority of endoscopic ultrasound-guided fine needle biopsy (EUS-FNB) over EUS-guided fine needle aspiration (EUS-FNA) remains controversial. Given the lack of studies analyzing histologic specimens acquired from EUS-FNB or EUS-FNA, we compared the proportion of the histologic core obtained from both techniques. A total of 58 consecutive patients with solid mass lesions were enrolled and randomly assigned to the EUS-FNA or EUS-FNB groups. The opposite needle was used after the failure of core tissue acquisition using the initial needle with up to three passes. Using computerized analyses of the scanned histologic slide, the overall area and the area of the histologic core portion in specimens obtained by the two techniques were compared. No significant differences were identified between the two groups with respect to demographic and clinical characteristics. Fewer needle passes were required to obtain core specimens in the FNB group (pcore (11.8%±19.5% vs 8.0%±11.1%, p=0.376) or in the diagnostic accuracy (80.6% vs 81.5%, p=0.935) between two groups. The proportion of histologic core and the diagnostic accuracy were comparable between the FNB and FNA groups. However, fewer needle passes were required to establish an accurate diagnosis in EUS-FNB.

  14. Metastatic renal cell carcinoma in the thyroid gland: ultrasonographic features and the diagnostic role of core needle biopsy

    Energy Technology Data Exchange (ETDEWEB)

    Song, Ok Kyu; Koo, Ja Seung; Kwak, Jin Young; Moon, Hee Jung; Yoon, Jung Hyun; Kim, Eun Kyung [Severance Hospital, Yonsei University College of Medicine, Seoul(Korea, Republic of)

    2017-07-15

    The aims of this study were to present the ultrasonographic (US) features of metastatic renal cell carcinoma (RCC) in the thyroid gland and to evaluate the diagnostic utility of fine needle aspiration (FNA) and core needle biopsy (CNB). Eight patients with nine metastatic RCC nodules in the thyroid glands who were treated from January 2002 to March 2015 in a single tertiary hospital were consecutively selected and retrospectively reviewed. US features and clinical history were obtained from the institution’s medical database. FNA was performed nine times on eight nodules and CNB was performed six times on six nodules. The diagnostic utility of FNA and CNB was evaluated. All nine nodules showed mass formation without diffuse thyroid involvement. On ultrasonography, metastatic RCC nodules were solid (100%), hypoechoic (100%), and ovalshaped nodules with a well-defined smooth margin (88.9%) and increased vascularity (100%, with 55% showing extensive vascularity). No calcifications were noted in any nodules. Lymph node metastasis and direct extension to nearby structures beyond the thyroid gland were not found. One FNA (11%) was able to confirm metastatic RCC, whereas all six CNBs confirmed metastatic RCC. Metastatic RCC appears as oval-shaped hypoechoic solid nodules with well-defined smooth margins, no calcifications, and increased vascularity on ultrasonography. Characteristic US features along with a previous history of RCC should raise clinical suspicion, and CNB should be performed to make an accurate diagnosis.

  15. Effectiveness of core biopsy for screen-detected breast lesions under 10 mm: implications for surgical management.

    Science.gov (United States)

    Farshid, Gelareh; Downey, Peter; Pieterse, Steve; Gill, P Grantley

    2017-09-01

    Technical advances have improved the detection of small mammographic lesions. In the context of mammographic screening, accurate sampling of these lesions by percutaneous biopsy is crucial in limiting diagnostic surgical biopsies, many of which show benign results. Women undergoing core biopsy between January 1997 and December 2007 for core histology, 345 women (43.0%) were immediately cleared of malignancy and 300 (37.4%) were referred for definitive cancer treatment. A further 157 women (19.6%) required diagnostic surgical biopsy because of indefinite or inadequate core results or radiological-pathological discordance, and one woman (0.1%) needed further imaging in 12 months. The open biopsies were malignant in 46 (29.3%) cases. The positive predictive value of malignant core biopsy was 100%. The negative predictive value for benign core results was 97.7%, and the false-negative rate was 2.6%. The lesion could not be visualized after core biopsy in 5.1% of women and in 4.0% of women with malignant core biopsies excision specimens did not contain residual malignancy. Excessive delays in surgery because of complications of core biopsy were not reported. Even at this small size range, core biopsy evaluation of screen-detected breast lesions is highly effective and accurate. A lesion miss rate of 3.1% and under-representation of lesions on core samples highlight the continued need for multidisciplinary collaboration and selective use of diagnostic surgical biopsy. © 2015 Royal Australasian College of Surgeons.

  16. Center of Cancer Nanotechnology Excellence for Translational Diagnostics

    Science.gov (United States)

    The Center of Cancer Nanotechnology Excellence for Translational Diagnostics, which forms the third cycle CCNE Program at Stanford University, is a consortium that has three highly synchronized Projects and three Cores.

  17. Plan-for-Gov[IT] - Planning for Governance of IT Method: use of the Techniques of "Text Retrieval" for mapping the expected support needs from IT Area to serve of the Corporation's Core-Business expectations

    Directory of Open Access Journals (Sweden)

    Altino José Mentzingen De Moraes

    2013-04-01

    Full Text Available The IT - Information Technology, in accordance with the philosophy of the IT Governance (and also as defined by Authors listed as follows requires its integration to the process of Strategic Planning of its Corporation, with the intention to align its actions with the Core-Business aiming at to reach the expected results by the IT Area. The question is how the IT can, under a methodological and direct way, to know how to interpret the expectations expressed by the Strategic Planning (a component of the Corporative Governance, in actions that are addressed to its Area in a practical manner and with an adequate tool kit related to the Frameworks (Models focused to the implementation of the IT Governance, for posterior creation of the necessary Effectiveness Indicators for monitoring about success level of the actions of IT in alignment with the Business. The result of this work is the proposal of the Text Retrieval and its subsequent validation (as a plausible resource for actual use to try to help the Governance of IT in its primary task of assisting the Corporation Core-Business, which was named as Plan-for- Gov[IT] - Planning for Governance of IT Method, which can be automated by the use of resources of "word finding" in Word Processors or in another software products with also this purpose.

  18. Functional requirements for core surveillance systems

    International Nuclear Information System (INIS)

    Andersson, T.

    2000-01-01

    Operating experience at Ringhals-2 has demonstrated the feasibility of a mixed core surveillance system comprised of fixed in-core detectors combined with the original movable detector system. A small number of fixed in-core detectors provide continuous measurement of the thermal margins while the movable detectors are used mainly at start-up to verify the expected power distribution. Reactor noise diagnostics and neural networks can further improve the monitoring system. The reliability of the movable detector system can be improved by mechanical simplification. Wear and maintenance costs are lowered if the required flux-mapping frequency is reduced. Improved computer codes make the measurement uncertainties less dependent on the number of instrumented positions. A mixed system requires new types of technical specifications. (author)

  19. Diagnostics for pellet experiments

    International Nuclear Information System (INIS)

    Johnson, R.R.

    1978-01-01

    The target diagnostics which are being used and planned in current laser driven ICF Experiments are described. Most of these diagnostics can be easily applied to future ion-beam fusion experiments. The status of laser fusion diagnostics has been much improved in the last 5 years and further improvements can be expected and should be available when the first ICF experiments using ion beams are performed. As an example, x-ray temporal and spatial resolutions are now approximately 5 psec and 3 μm, which is approximately a factor of 4 better than the resolution reported in the first implosion experiments. As one plans ahead for ion-beam fusion experiments it should be emphasized that high yield experiments are easier to diagnose provided adequate shielding is employed. However, in the event that the first high yield experiments fail it will be necessary to have diagnostics available to determine where the problems lie. In laser fusion it is interesting to note that higher laser powers are required now for breakeven experiments than first anticipated, mainly because some aspects of the laser-interaction physics were not recognized until the experiments were carefully diagnosed. Thus as has been pointed out, it may be necessary to increase the energy of the ion-beam driver to enable us to do breakeven experiments with high confidence

  20. [Variations in the diagnostic confirmation process between breast cancer mass screening units].

    Science.gov (United States)

    Natal, Carmen; Fernández-Somoano, Ana; Torá-Rocamora, Isabel; Tardón, Adonina; Castells, Xavier

    2016-01-01

    To analyse variations in the diagnostic confirmation process between screening units, variations in the outcome of each episode and the relationship between the use of the different diagnostic confirmation tests and the lesion detection rate. Observational study of variability of the standardised use of diagnostic and lesion detection tests in 34 breast cancer mass screening units participating in early-detection programmes in three Spanish regions from 2002-2011. The diagnostic test variation ratio in percentiles 25-75 ranged from 1.68 (further appointments) to 3.39 (fine-needle aspiration). The variation ratio in detection rates of benign lesions, ductal carcinoma in situ and invasive cancer were 2.79, 1.99 and 1.36, respectively. A positive relationship between rates of testing and detection rates was found with fine-needle aspiration-benign lesions (R(2): 0.53), fine-needle aspiration-invasive carcinoma (R(2): 0 28), core biopsy-benign lesions (R(2): 0.64), core biopsy-ductal carcinoma in situ (R(2): 0.61) and core biopsy-invasive carcinoma (R(2): 0.48). Variation in the use of invasive tests between the breast cancer screening units participating in early-detection programmes was found to be significantly higher than variations in lesion detection. Units which conducted more fine-needle aspiration tests had higher benign lesion detection rates, while units that conducted more core biopsies detected more benign lesions and cancer. Copyright © 2016 SESPAS. Published by Elsevier Espana. All rights reserved.

  1. Reversed field pinch diagnostics

    International Nuclear Information System (INIS)

    Weber, P.G.

    1986-01-01

    The Reversed Field Pinch (RFP) is a toroidal, axisymmetric magnetic confinement configuration characterized by a magnetic field configuration in which the toroidal magnetic field is of similar strength to the poloidal field, and is reversed at the edge compared to the center. The RFP routinely operates at high beta, and is a strong candidate for a compact fusion device. Relevant attributes of the configuration will be presented, together with an overview of present and planned experiments and their diagnostics. RFP diagnostics are in many ways similar to those of other magnetic confinement devices (such as tokamaks); these lectures will point out pertinent differences, and will present some diagnostics which provide special insights into unique attributes of the RFP

  2. Diagnostic imaging in pregraduate integrated curricula

    International Nuclear Information System (INIS)

    Kainberger, F.; Kletter, K.

    2007-01-01

    Pregraduate medical curricula are currently undergoing a reform process that is moving away from a traditional discipline-related structure and towards problem-based integrated forms of teaching. Imaging sciences, with their inherently technical advances, are specifically influenced by the effects of paradigm shifts in medical education. The teaching of diagnostic radiology should be based on the definition of three core competencies: in vivo visualization of normal and abnormal morphology and function, diagnostic reasoning, and interventional treatment. On the basis of these goals, adequate teaching methods and e-learning tools should be implemented by focusing on case-based teaching. Teaching materials used in the fields of normal anatomy, pathology, and clinical diagnosis may help diagnostic radiology to play a central role in modern pregraduate curricula. (orig.)

  3. [Diagnostic imaging in pregraduate integrated curricula].

    Science.gov (United States)

    Kainberger, F; Kletter, K

    2007-11-01

    Pregraduate medical curricula are currently undergoing a reform process that is moving away from a traditional discipline-related structure and towards problem-based integrated forms of teaching. Imaging sciences, with their inherently technical advances, are specifically influenced by the effects of paradigm shifts in medical education. The teaching of diagnostic radiology should be based on the definition of three core competencies: in vivo visualization of normal and abnormal morphology and function, diagnostic reasoning, and interventional treatment. On the basis of these goals, adequate teaching methods and e-learning tools should be implemented by focusing on case-based teaching. Teaching materials used in the fields of normal anatomy, pathology, and clinical diagnosis may help diagnostic radiology to play a central role in modern pregraduate curricula.

  4. The PWR cores management

    International Nuclear Information System (INIS)

    Barral, J.C.; Rippert, D.; Johner, J.

    2000-01-01

    During the meeting of the 25 january 2000, organized by the SFEN, scientists and plant operators in the domain of the PWR debated on the PWR cores management. The five first papers propose general and economic information on the PWR and also the fast neutron reactors chains in the electric power market: statistics on the electric power industry, nuclear plant unit management, the ITER project and the future of the thermonuclear fusion, the treasurer's and chairman's reports. A second part offers more technical papers concerning the PWR cores management: performance and optimization, in service load planning, the cores management in the other countries, impacts on the research and development programs. (A.L.B.)

  5. A study to evaluate the efficacy of image-guided core biopsy in the diagnosis and management of lymphoma-Results in 103 biopsies

    International Nuclear Information System (INIS)

    Vandervelde, C.; Kamani, T.; Varghese, A.; Ramesar, K.; Grace, R.; Howlett, D.C.

    2008-01-01

    The reason for this study was to evaluate the ability of image-guided core biopsy to replace surgical excision by providing sufficient diagnostic and treatment information. All consecutive image-guided core biopsies in patients with a final diagnosis of lymphoma over a 6-year period at our institution were collected retrospectively. Case notes and pathology reports were reviewed and the diagnostic techniques used were recorded. Pathology reports were graded according to their diagnostic completeness and their ability to provide treatment information. Out of a total of 328 instances of lymphoma, 103 image-guided core biopsies were performed in 96 patients. In 78% of these, the diagnostic information obtained from the biopsy provided a fully graded and subtyped diagnosis of lymphoma with sufficient information to initiate therapy. In the head and neck 67% of core biopsies were fully diagnostic for treatment purposes compared to 91% in the thorax, abdomen and pelvis. Image-guided core biopsy has a number of cost and safety advantages over surgical excision biopsy and in suitable cases it can obviate the need for surgery in cases of suspected lymphoma. This is especially relevant for elderly patients and those with poor performance status

  6. A study to evaluate the efficacy of image-guided core biopsy in the diagnosis and management of lymphoma-Results in 103 biopsies

    Energy Technology Data Exchange (ETDEWEB)

    Vandervelde, C. [Department of Radiology, Eastbourne District General Hospital, Kings Drive, Eastbourne, East Sussex BN21 2UD (United Kingdom)], E-mail: clivevandervelde@gmail.com; Kamani, T. [Department of ENT Surgery, Eastbourne District General Hospital, Kings Drive, Eastbourne, East Sussex BN21 2UD (United Kingdom)], E-mail: tkamany@yahoo.com; Varghese, A. [Department of Radiology, Eastbourne District General Hospital, Kings Drive, Eastbourne, East Sussex BN21 2UD (United Kingdom)], E-mail: vargheseajay@hotmail.com; Ramesar, K. [Department of Histopathology, Eastbourne District General Hospital, Kings Drive, Eastbourne, East Sussex BN21 2UD (United Kingdom)], E-mail: keith.ramesar@esht.nhs.uk; Grace, R. [Department of Haematology, Eastbourne District General Hospital, Kings Drive, Eastbourne, East Sussex BN21 2UD (United Kingdom)], E-mail: richard.grace@esht.nhs.uk; Howlett, D.C. [Department of Radiology, Eastbourne District General Hospital, Kings Drive, Eastbourne, East Sussex BN21 2UD (United Kingdom)], E-mail: david.howlett@esht.nhs.uk

    2008-04-15

    The reason for this study was to evaluate the ability of image-guided core biopsy to replace surgical excision by providing sufficient diagnostic and treatment information. All consecutive image-guided core biopsies in patients with a final diagnosis of lymphoma over a 6-year period at our institution were collected retrospectively. Case notes and pathology reports were reviewed and the diagnostic techniques used were recorded. Pathology reports were graded according to their diagnostic completeness and their ability to provide treatment information. Out of a total of 328 instances of lymphoma, 103 image-guided core biopsies were performed in 96 patients. In 78% of these, the diagnostic information obtained from the biopsy provided a fully graded and subtyped diagnosis of lymphoma with sufficient information to initiate therapy. In the head and neck 67% of core biopsies were fully diagnostic for treatment purposes compared to 91% in the thorax, abdomen and pelvis. Image-guided core biopsy has a number of cost and safety advantages over surgical excision biopsy and in suitable cases it can obviate the need for surgery in cases of suspected lymphoma. This is especially relevant for elderly patients and those with poor performance status.

  7. Test-Access Planning and Test Scheduling for Embedded Core-Based System Chips

    OpenAIRE

    Goel, Sandeep Kumar

    2005-01-01

    Advances in the semiconductor process technology enable the creation of a complete system on one single die, the so-called system chip or SOC. To reduce time-to-market for large SOCs, reuse of pre-designed and pre-veried blocks called cores is employed. Like the design style, testing of SOCs can be best approached in a core-based fashion. In order to enable core-based test development, an embedded core should be isolated from its surrounding circuitry and electrical test access from chip pins...

  8. Options for Parallelizing a Planning and Scheduling Algorithm

    Science.gov (United States)

    Clement, Bradley J.; Estlin, Tara A.; Bornstein, Benjamin D.

    2011-01-01

    Space missions have a growing interest in putting multi-core processors onboard spacecraft. For many missions processing power significantly slows operations. We investigate how continual planning and scheduling algorithms can exploit multi-core processing and outline different potential design decisions for a parallelized planning architecture. This organization of choices and challenges helps us with an initial design for parallelizing the CASPER planning system for a mesh multi-core processor. This work extends that presented at another workshop with some preliminary results.

  9. Access management in Safer Transportation Network Planning : safety principles, planning framework, and library information.

    NARCIS (Netherlands)

    Hummel, T.

    2001-01-01

    This report is one in a series of publications, used in the development of the network planning tool ‘Safer Transportation Network Planning’ (Safer-TNP). The publications were used to guide the development of planning structures, diagnostic tools, planning recommendations, and research information

  10. Route management in Safer Transportation Network Planning : safety principles, planning framework, and library information.

    NARCIS (Netherlands)

    Hummel, T.

    2001-01-01

    This report is one in a series of publications, used in the development of the network planning tool ‘Safer Transportation Network Planning’ (Safer-TNP). The publications were used to guide the development of planning structures, diagnostic tools, planning recommendations, and research information

  11. Diagnostic grand rounds: A new teaching concept to train diagnostic reasoning

    International Nuclear Information System (INIS)

    Stieger, Stefan; Praschinger, Andrea; Kletter, Kurt; Kainberger, Franz

    2011-01-01

    Introduction: Diagnostic reasoning is a core skill in teaching and learning in undergraduate curricula. Diagnostic grand rounds (DGRs) as a subform of grand rounds are intended to train the students' skills in the selection of appropriate tests and in the interpretation of test results. The aim of this study was to test DGRs for their ability to improve diagnostic reasoning by using a pre-post-test design. Methods: During one winter term, all 398 fifth-year students (36.1% male, 63.9% female) solved 23 clinical cases presented in 8 DGRs. In an online questionnaire, a Diagnostic Thinking Inventory (DTI) with 41 items was evaluated for flexibility in thinking and structure of knowledge in memory. Results were correlated with those from a summative multiple-choice knowledge test and of the learning objectives in a logbook. Results: The students' DTI scores in the post-test were significantly higher than those reported in the pre-test. DTI scores at either testing time did not correlate with medical knowledge as assessed by a multiple-choice knowledge test. Abilities acquired during clinical clerkships as documented in a logbook could only account for a small proportion of the increase in the flexibility subscale score. This effect still remained significant after accounting for potential confounders. Conclusion: Establishing DGRs proofed to be an effective way of successfully improving both students' diagnostic reasoning and the ability to select the appropriate test method in routine clinical practice.

  12. Diagnostic grand rounds: A new teaching concept to train diagnostic reasoning

    Energy Technology Data Exchange (ETDEWEB)

    Stieger, Stefan, E-mail: stefan.stieger@univie.ac.at [Department of Basic Psychological Research, School of Psychology, University of Vienna, Liebiggasse 5, A-1010 Vienna (Austria); Praschinger, Andrea, E-mail: andrea.praschinger@meduniwien.ac.at [Core Unit for Medical Education (BEMAW), Medical University of Vienna, Spitalgasse 23, BT87, P.O. 10, A-1097 Vienna (Austria); Kletter, Kurt, E-mail: kurt.kletter@meduniwien.ac.at [Department of Nuclear Medicine, General Hospital of Vienna, Waehringer Guertel 18-20, A-1090 Vienna (Austria); Kainberger, Franz, E-mail: franz.kainberger@meduniwien.ac.at [Department of Radiology, General Hospital of Vienna, Waehringer Guertel 18-20, A-1090 Vienna (Austria)

    2011-06-15

    Introduction: Diagnostic reasoning is a core skill in teaching and learning in undergraduate curricula. Diagnostic grand rounds (DGRs) as a subform of grand rounds are intended to train the students' skills in the selection of appropriate tests and in the interpretation of test results. The aim of this study was to test DGRs for their ability to improve diagnostic reasoning by using a pre-post-test design. Methods: During one winter term, all 398 fifth-year students (36.1% male, 63.9% female) solved 23 clinical cases presented in 8 DGRs. In an online questionnaire, a Diagnostic Thinking Inventory (DTI) with 41 items was evaluated for flexibility in thinking and structure of knowledge in memory. Results were correlated with those from a summative multiple-choice knowledge test and of the learning objectives in a logbook. Results: The students' DTI scores in the post-test were significantly higher than those reported in the pre-test. DTI scores at either testing time did not correlate with medical knowledge as assessed by a multiple-choice knowledge test. Abilities acquired during clinical clerkships as documented in a logbook could only account for a small proportion of the increase in the flexibility subscale score. This effect still remained significant after accounting for potential confounders. Conclusion: Establishing DGRs proofed to be an effective way of successfully improving both students' diagnostic reasoning and the ability to select the appropriate test method in routine clinical practice.

  13. Plasma Diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Zaveryaev, V [Kurchatov Institute, Moscow (Russian Federation); others, and

    2012-09-15

    The success in achieving peaceful fusion power depends on the ability to control a high temperature plasma, which is an object with unique properties, possibly the most complicated object created by humans. Over years of fusion research a new branch of science has been created, namely plasma diagnostics, which involves knowledge of almost all fields of physics, from electromagnetism to nuclear physics, and up-to-date progress in engineering and technology (materials, electronics, mathematical methods of data treatment). Historically, work on controlled fusion started with pulsed systems and accordingly the methods of plasma parameter measurement were first developed for short lived and dense plasmas. Magnetically confined hot plasmas require the creation of special experimental techniques for diagnostics. The diagnostic set is the most scientifically intensive part of a plasma device. During many years of research operation some scientific tasks have been solved while new ones arose. New tasks often require significant changes in the diagnostic system, which is thus a very flexible part of plasma machines. Diagnostic systems are designed to solve several tasks. As an example here are the diagnostic tasks for the International Thermonuclear Experimental Reactor - ITER: (1) Measurements for machine protection and basic control; (2) Measurements for advanced control; (3) Additional measurements for performance evaluation and physics. Every new plasma machine is a further step along the path to the main goal - controlled fusion - and nobody knows in advance what new phenomena will be met on the way. So in the planning of diagnostic construction we should keep in mind further system upgrading to meet possible new scientific and technical challenges. (author)

  14. Percutaneous computed tomography-guided core needle biopsy of soft tissue tumors: results and correlation with surgical specimen analysis

    Energy Technology Data Exchange (ETDEWEB)

    Chojniak, Rubens; Grigio, Henrique Ramos; Bitencourt, Almir Galvao Vieira; Pinto, Paula Nicole Vieira; Tyng, Chiang J.; Cunha, Isabela Werneck da; Aguiar Junior, Samuel; Lopes, Ademar, E-mail: chojniak@uol.com.br [Hospital A.C. Camargo, Sao Paulo, SP (Brazil)

    2012-09-15

    Objective: To evaluate the efficacy of percutaneous computed tomography (CT)-guided core needle biopsy of soft tissue tumors in obtaining appropriate samples for histological analysis, and compare its diagnosis with the results of the surgical pathology as available. Materials and Methods: The authors reviewed medical records, imaging and histological reports of 262 patients with soft-tissue tumors submitted to CT-guided core needle biopsy in an oncologic reference center between 2003 and 2009. Results: Appropriate samples were obtained in 215 (82.1%) out of the 262 patients. The most prevalent tumors were sarcomas (38.6%), metastatic carcinomas (28.8%), benign mesenchymal tumors (20.5%) and lymphomas (9.3%). Histological grading was feasible in 92.8% of sarcoma patients, with the majority of them (77.9%) being classified as high grade tumors. Out of the total sample, 116 patients (44.3%) underwent surgical excision and diagnosis confirmation. Core biopsy demonstrated 94.6% accuracy in the identification of sarcomas, with 96.4% sensitivity and 89.5% specificity. A significant intermethod agreement about histological grading was observed between core biopsy and surgical resection (p < 0.001; kappa = 0.75). Conclusion: CT-guided core needle biopsy demonstrated a high diagnostic accuracy in the evaluation of soft tissue tumors as well as in the histological grading of sarcomas, allowing an appropriate therapeutic planning (author)

  15. Management of Logistics Planning

    OpenAIRE

    Bjørnar Aas; Stein W. Wallace

    2010-01-01

    Logistics problems are gradually becoming more complex and a better understanding of logistics management as a subject is a key to deal with the new challenges. A core element of logistics management is logistics planning, which substitutes for low customer service levels, high waste, and the use of buffers and slacks in the execution of logistic activities. Furthermore, the availability of information and problem-solving capabilities are established as the core parts of logistics planning. B...

  16. Time-dependent electron temperature diagnostics for high-power aluminum z-pinch plasmas

    International Nuclear Information System (INIS)

    Sanford, T.W.L.; Nash, T.J.; Mock, R.C.

    1996-08-01

    Time-resolved x-ray pinhole photographs and time-integrated radially-resolved x-ray crystal-spectrometer measurements of azimuthally-symmetric aluminum-wire implosions suggest that the densest phase of the pinch is composed of a hot plasma core surrounded by a cooler plasma halo. The slope of the free-bound x-ray continuum, provides a time-resolved, model-independent diagnostic of the core electron temperature. A simultaneous measurement of the time-resolved K-shell line spectra provides the electron temperature of the spatially averaged plasma. Together, the two diagnostics support a 1-D Radiation-Hydrodynamic model prediction of a plasma whose thermalization on axis produces steep radial gradients in temperature, from temperatures in excess of a kilovolt in the core to below a kilovolt in the surrounding plasma halo

  17. Upgrading the reactor noise diagnostic systems at the Paks NPP

    International Nuclear Information System (INIS)

    Czibok, T.; Dezsoe, Z.; Kiss, K.; Krinizs, K.; Lipcsei, S.

    2002-01-01

    The paper reports on the actual step in upgrading process of the reactor noise diagnostic systems at Paks NPP. This step has mainly a technical character. Renewal of facilities for signal conditioning and for data acquisition is going on. Autonomous systems at each of the four reactor units will be able to acquire a set of data series which can be arbitrarily chosen from the whole set of several hundred in-core neutron and other signals. The autonomous systems can be remotely controlled by a central computer through the local network. Modularity and extensibility are important features of the new systems: the size of the set of available signals can be extended and new modules for more advanced evaluations can be installed later. Present plans for system hardware upgrading are outlined, together with some technical details of measurement control, data acquisition moduls and network communication.(abstract)

  18. Feasibility study for core protection calculator development

    International Nuclear Information System (INIS)

    In, W. K.; Han, J. B.

    2003-06-01

    This project confirmed the development feasibility of new digital core protection system and established development plan for ITOPS that can replace the CPC system. The development plan and implementation strategy for ITOPS proposed in this project will be useful to successfully develop advanced digital core protection system for the CPC replacement in KSNP plants. YGN units 3 and 4 are expected to replace the CPC system within next ten years and the other KSNP plants are followed. The localization model for advanced digital core protection system, ITOPS, is judged to upgrade the Common Q CPC system in both system configuration and algorithm performance and can reduce the cost for supply and maintenance. Hence, ITOPS is expected to be installed in new Korea nuclear power plants and also useful to export the associated technology in the future

  19. The Project of Planning

    DEFF Research Database (Denmark)

    Flyvbjerg, Bent

    1986-01-01

    This article contains an interview with John Friedmann. The interview covers two core areas in John Friedmann's work: (a) The history of planning, from the beginning of the industrial era till today and (b) radical planning and social mobilization. In relation to radical planning and social mobil...

  20. RANZAR Body Systems Framework of diagnostic imaging examination descriptors

    International Nuclear Information System (INIS)

    Pitman, Alexander D.; Penlington, Lisa; Doromal, Darren; Vukolova, Natalia; Slater, Gregory

    2014-01-01

    A unified and logical system of descriptors for diagnostic imaging examinations and procedures is a desirable resource for radiology in Australia and New Zealand and is needed to support core activities of RANZCR. Existing descriptor systems available in Australia and New Zealand (including the Medicare DIST and the ACC Schedule) have significant limitations and are inappropriate for broader clinical application. An anatomically based grid was constructed, with anatomical structures arranged in rows and diagnostic imaging modalities arranged in columns (including nuclear medicine and positron emission tomography). The grid was segregated into five body systems. The cells at the intersection of an anatomical structure row and an imaging modality column were populated with short, formulaic descriptors of the applicable diagnostic imaging examinations. Clinically illogical or physically impossible combinations were ‘greyed out’. Where the same examination applied to different anatomical structures, the descriptor was kept identical for the purposes of streamlining. The resulting Body Systems Framework of diagnostic imaging examination descriptors lists all the reasonably common diagnostic imaging examinations currently performed in Australia and New Zealand using a unified grid structure allowing navigation by both referrers and radiologists. The Framework has been placed on the RANZCR website and is available for access free of charge by registered users. The Body Systems Framework of diagnostic imaging examination descriptors is a system of descriptors based on relationships between anatomical structures and imaging modalities. The Framework is now available as a resource and reference point for the radiology profession and to support core College activities.

  1. RANZCR Body Systems Framework of diagnostic imaging examination descriptors.

    Science.gov (United States)

    Pitman, Alexander G; Penlington, Lisa; Doromal, Darren; Slater, Gregory; Vukolova, Natalia

    2014-08-01

    A unified and logical system of descriptors for diagnostic imaging examinations and procedures is a desirable resource for radiology in Australia and New Zealand and is needed to support core activities of RANZCR. Existing descriptor systems available in Australia and New Zealand (including the Medicare DIST and the ACC Schedule) have significant limitations and are inappropriate for broader clinical application. An anatomically based grid was constructed, with anatomical structures arranged in rows and diagnostic imaging modalities arranged in columns (including nuclear medicine and positron emission tomography). The grid was segregated into five body systems. The cells at the intersection of an anatomical structure row and an imaging modality column were populated with short, formulaic descriptors of the applicable diagnostic imaging examinations. Clinically illogical or physically impossible combinations were 'greyed out'. Where the same examination applied to different anatomical structures, the descriptor was kept identical for the purposes of streamlining. The resulting Body Systems Framework of diagnostic imaging examination descriptors lists all the reasonably common diagnostic imaging examinations currently performed in Australia and New Zealand using a unified grid structure allowing navigation by both referrers and radiologists. The Framework has been placed on the RANZCR website and is available for access free of charge by registered users. The Body Systems Framework of diagnostic imaging examination descriptors is a system of descriptors based on relationships between anatomical structures and imaging modalities. The Framework is now available as a resource and reference point for the radiology profession and to support core College activities. © 2014 The Royal Australian and New Zealand College of Radiologists.

  2. FAA Flight Plan 2009-2013

    Science.gov (United States)

    2009-01-01

    The Flight Plan is the strategic plan for the agency, the plan to help us prepare for the future. The majority of FAAs responsibilities are our core functionsour everyday roles and responsibilitieswhich are not specifically highlighted in th...

  3. TMI-2 reactor-vessel head removal and damaged-core-removal planning

    International Nuclear Information System (INIS)

    Logan, J.A.; Hultman, C.W.; Lewis, T.J.

    1982-01-01

    A major milestone in the cleanup and recovery effort at TMI-2 will be the removal of the reactor vessel closure head, planum, and damaged core fuel material. The data collected during these operations will provide the nuclear power industry with valuable information on the effects of high-temperature-dissociated coolant on fuel cladding, fuel materials, fuel support structural materials, neutron absorber material, and other materials used in reactor structural support components and drive mechanisms. In addition, examination of these materials will also be used to determine accident time-temperature histories in various regions of the core. Procedures for removing the reactor vessel head and reactor core are presented

  4. Software for Project-Based Learning of Robot Motion Planning

    Science.gov (United States)

    Moll, Mark; Bordeaux, Janice; Kavraki, Lydia E.

    2013-01-01

    Motion planning is a core problem in robotics concerned with finding feasible paths for a given robot. Motion planning algorithms perform a search in the high-dimensional continuous space of robot configurations and exemplify many of the core algorithmic concepts of search algorithms and associated data structures. Motion planning algorithms can…

  5. Design of full MOX core in ABWR

    International Nuclear Information System (INIS)

    Kinoshita, Y.; Hirose, T.; Sasagawa, M.; Sakuma, T

    1999-01-01

    A Full MOX-ABWR, loaded with mixed-oxide (MOX) fuels of up to 100% of the core, is planned. Increased MOX fuel utilization will result in greater savings of uranium. Studies on the fuel rod thermal-mechanical design, the core design and the safety evaluation have been made, and the results are summarized in this paper. To sum it all up, the safety of the Full MOX-ABWR has been confirmed through design evaluations adequately considering the MOX fuel and core characteristics. (author)

  6. Physics R and D in support of ITER/BPX diagnostic development

    International Nuclear Information System (INIS)

    Donne, A.J.H.; Boivin, R.; Costley, A.E.

    2003-01-01

    The development of diagnostics for a next step burning plasma experiment (BPX) is a major challenge. Within the International Tokamak Physics Activity (ITPA), one Topical Group (TG) specialises in diagnostics and aims to support the development and design of the needed systems. Several diagnostics issues have been identified as 'high priority' and form the focus of current work of the TG. The core of this paper is a presentation and discussion of recent progress in the field of these high priority research topics. Moreover, the status of the recently initiated International Diagnostic Database will be briefly described. (author)

  7. Proposed Diagnostic Criteria for Smartphone Addiction.

    Science.gov (United States)

    Lin, Yu-Hsuan; Chiang, Chih-Lin; Lin, Po-Hsien; Chang, Li-Ren; Ko, Chih-Hung; Lee, Yang-Han; Lin, Sheng-Hsuan

    2016-01-01

    Global smartphone penetration has led to unprecedented addictive behaviors. The aims of this study are to develop diagnostic criteria of smartphone addiction and to examine the discriminative ability and the validity of the diagnostic criteria. We developed twelve candidate criteria for characteristic symptoms of smartphone addiction and four criteria for functional impairment caused by excessive smartphone use. The participants consisted of 281 college students. Each participant was systematically assessed for smartphone-using behaviors by psychiatrist's structured diagnostic interview. The sensitivity, specificity, and diagnostic accuracy of the candidate symptom criteria were analyzed with reference to the psychiatrists' clinical global impression. The optimal model selection with its cutoff point of the diagnostic criteria differentiating the smartphone addicted subjects from non-addicted subjects was then determined by the best diagnostic accuracy. Six symptom criteria model with optimal cutoff point were determined based on the maximal diagnostic accuracy. The proposed smartphone addiction diagnostic criteria consisted of (1) six symptom criteria, (2) four functional impairment criteria and (3) exclusion criteria. Setting three symptom criteria as the cutoff point resulted in the highest diagnostic accuracy (84.3%), while the sensitivity and specificity were 79.4% and 87.5%, respectively. We suggested determining the functional impairment by two or more of the four domains considering the high accessibility and penetration of smartphone use. The diagnostic criteria of smartphone addiction demonstrated the core symptoms "impaired control" paralleled with substance related and addictive disorders. The functional impairment involved multiple domains provide a strict standard for clinical assessment.

  8. Proposed Diagnostic Criteria for Smartphone Addiction.

    Directory of Open Access Journals (Sweden)

    Yu-Hsuan Lin

    Full Text Available Global smartphone penetration has led to unprecedented addictive behaviors. The aims of this study are to develop diagnostic criteria of smartphone addiction and to examine the discriminative ability and the validity of the diagnostic criteria.We developed twelve candidate criteria for characteristic symptoms of smartphone addiction and four criteria for functional impairment caused by excessive smartphone use. The participants consisted of 281 college students. Each participant was systematically assessed for smartphone-using behaviors by psychiatrist's structured diagnostic interview. The sensitivity, specificity, and diagnostic accuracy of the candidate symptom criteria were analyzed with reference to the psychiatrists' clinical global impression. The optimal model selection with its cutoff point of the diagnostic criteria differentiating the smartphone addicted subjects from non-addicted subjects was then determined by the best diagnostic accuracy.Six symptom criteria model with optimal cutoff point were determined based on the maximal diagnostic accuracy. The proposed smartphone addiction diagnostic criteria consisted of (1 six symptom criteria, (2 four functional impairment criteria and (3 exclusion criteria. Setting three symptom criteria as the cutoff point resulted in the highest diagnostic accuracy (84.3%, while the sensitivity and specificity were 79.4% and 87.5%, respectively. We suggested determining the functional impairment by two or more of the four domains considering the high accessibility and penetration of smartphone use.The diagnostic criteria of smartphone addiction demonstrated the core symptoms "impaired control" paralleled with substance related and addictive disorders. The functional impairment involved multiple domains provide a strict standard for clinical assessment.

  9. Proton storage ring (PSR) diagnostics and control system

    International Nuclear Information System (INIS)

    Clout, P.

    1983-01-01

    When any new accelerator or storage ring is built that advances the state of the art, the diagnostic system becomes extremely important in tuning the facility to full specification. This paper will discuss the various diagnostic devices planned or under construction for the PSR and their connection into the control system

  10. Institutional Management of Core Facilities during Challenging Financial Times

    OpenAIRE

    Haley, Rand

    2011-01-01

    The economic downturn is likely to have lasting effects on institutions of higher education, prioritizing proactive institutional leadership and planning. Although by design, core research facilities are more efficient and effective than supporting individual pieces of research equipment, cores can have significant underlying financial requirements and challenges. This paper explores several possible institutional approaches to managing core facilities during challenging financial times.

  11. Institutional management of core facilities during challenging financial times.

    Science.gov (United States)

    Haley, Rand

    2011-12-01

    The economic downturn is likely to have lasting effects on institutions of higher education, prioritizing proactive institutional leadership and planning. Although by design, core research facilities are more efficient and effective than supporting individual pieces of research equipment, cores can have significant underlying financial requirements and challenges. This paper explores several possible institutional approaches to managing core facilities during challenging financial times.

  12. Diagnostic Yield of CT-Guided Percutaneous Transthoracic Needle Biopsy for Diagnosis of Anterior Mediastinal Masses.

    Science.gov (United States)

    Petranovic, Milena; Gilman, Matthew D; Muniappan, Ashok; Hasserjian, Robert P; Digumarthy, Subba R; Muse, Victorine V; Sharma, Amita; Shepard, Jo-Anne O; Wu, Carol C

    2015-10-01

    The purpose of this study was to evaluate the diagnostic yield and accuracy of CT-guided percutaneous biopsy of anterior mediastinal masses and assess prebiopsy characteristics that may help to select patients with the highest diagnostic yield. Retrospective review of all CT-guided percutaneous biopsies of the anterior mediastinum conducted at our institution from January 2003 through December 2012 was performed to collect data regarding patient demographics, imaging characteristics of biopsied masses, presence of complications, and subsequent surgical intervention or medical treatment (or both). Cytology, core biopsy pathology, and surgical pathology results were recorded. A per-patient analysis was performed using two-tailed t test, Fisher's exact test, and Pearson chi-square test. The study cohort included 52 patients (32 men, 20 women; mean age, 49 years) with mean diameter of mediastinal mass of 6.9 cm. Diagnostic yield of CT-guided percutaneous biopsy was 77% (40/52), highest for thymic neoplasms (100% [11/11]). Non-diagnostic results were seen in 12 of 52 patients (23%), primarily in patients with lymphoma (75% [9/12]). Fine-needle aspiration yielded the correct diagnosis in 31 of 52 patients (60%), and core biopsy had a diagnostic rate of 77% (36/47). None of the core biopsies were discordant with surgical pathology. There was no statistically significant difference between the diagnostic and the nondiagnostic groups in patient age, lesion size, and presence of necrosis. The complication rate was 3.8% (2/52), all small self-resolving pneumothoraces. CT-guided percutaneous biopsy is a safe diagnostic procedure with high diagnostic yield (77%) for anterior mediastinal lesions, highest for thymic neoplasms (100%), and can potentially obviate more invasive procedures.

  13. Analysis of prostate cancer localization toward improved diagnostic accuracy of transperineal prostate biopsy

    Directory of Open Access Journals (Sweden)

    Yoshiro Sakamoto

    2014-09-01

    Conclusions: The concordance of prostate cancer between prostatectomy specimens and biopsies is comparatively favorable. According to our study, the diagnostic accuracy of transperineal prostate biopsy can be improved in our institute by including the anterior portion of the Apex-Mid and Mid regions in the 12-core biopsy or 16-core biopsy, such that a 4-core biopsy of the anterior portion is included.

  14. Sixth meeting of the ITPA Topical Group on Diagnostics

    International Nuclear Information System (INIS)

    Donne, A.J.H.; Costley, A.E.

    2004-01-01

    The Sixth Meeting of the International Tokamak Physics Activities (ITPA) Topical Group (TG) on Diagnostics was held at JAERI, Naka from 19-21 February 2004. This meeting was combined with a Progress Meeting on ITER/BPX (burning plasma experiment) relevant diagnostic developments on-going in Japan. For the first time, ITPA members from China, as well as observers from South Korea, attended. In addition, an associated sub-meeting was held at General Atomics, San Diego, 23-24 April, immediately after the 15th Topical Conference on High Temperature Plasma Diagnostics. At the sub-meeting a special one-day session was devoted to issues related to beam-aided spectroscopy. In total more than 50 participants attended the meetings and all ITER partners were represented. The key topics reviewed and discussed at the TG meeting were: (i) the overall status of diagnostics developments for ITER, (ii) the progress in the research on the designated high priority topics, (iii) the progress with some key ITER/BPX-relevant diagnostic developments ongoing in the ITPA participant laboratories, (iv) the progress and plans for the work of the specialist working groups, (v) the status and plans for the International Diagnostic Database

  15. Knowledge-Based operation planning system for boiling water reactors

    International Nuclear Information System (INIS)

    Tatsuya Iwamoto; Shungo Sakurai; Hitoshi Uematsu; Makoto Tsuiki

    1987-01-01

    A knowledge-Based Boiling Water Reactor operation planning system was developed to support core operators or core management engineers in making core operation plans, by automatically generating suboptimum core operation procedures. The procedures are obtained by searching a branching tree of the possible core status (nodes) and the elementary operations to change the core status (branches). A path that ends at the target node, and contains only operationally feasible nodes can be a candidate of the solution. The core eigenvalue, the power distribution and the thermal limit parameters at key points are calculated by running a three-dimensional (3-D) BWR core physics simulator to examine the feasibility of the nodes and the performance of candidates. To obtain a practically acceptable solution within a reasonable time rather than making a time-consuming effort to get the optimum one, the Depth-First-Search method, together with the heuristic branch-bounding, was used to search the branching tree. The system was applied to actual operation plannings with real plant data, and gave satisfactory results. It can be concluded that the system can be applied to generate core operation procedures as a substitute for core management experts

  16. Small business development for molecular diagnostics.

    Science.gov (United States)

    Anagostou, Anthanasia; Liotta, Lance A

    2012-01-01

    Molecular profiling, which is the application of molecular diagnostics technology to tissue and blood -specimens, is an integral element in the new era of molecular medicine and individualized therapy. Molecular diagnostics is a fertile ground for small business development because it can generate products that meet immediate demands in the health-care sector: (a) Detection of disease risk, or early-stage disease, with a higher specificity and sensitivity compared to previous testing methods, and (b) "Companion diagnostics" for stratifying patients to receive a treatment choice optimized to their individual disease. This chapter reviews the promise and challenges of business development in this field. Guidelines are provided for the creation of a business model and the generation of a marketing plan around a candidate molecular diagnostic product. Steps to commercialization are outlined using existing molecular diagnostics companies as learning examples.

  17. Engineering task plan for the development, fabrication and installation of rotary mode core sample truck grapple hoist box level wind system

    International Nuclear Information System (INIS)

    BOGER, R.M.

    1999-01-01

    This Engineering Task Plan is to design, generate fabrication drawings, fabricate, test, and install the grapple hoist level wind system for Rotary Mode Core Sample Trucks (RMCST) 3 and 4. Deliverables will include generating fabrication drawings, fabrication of one level wind system, updating fabrication drawings as required, and installation of level wind systems on RMCST 3 or 4. The installation of the level wind systems will be done during a preventive maintenance outage

  18. Nuclear start-up, testing and core management of the Fast Test Reactor (FTR)

    International Nuclear Information System (INIS)

    Bennett, R.A.; Daughtry, J.W.; Harris, R.A.; Jones, D.H.; Nelson, J.V.; Rawlins, J.A.; Rothrock, R.B.; Sevenich, R.A.; Zimmerman, B.D.

    1980-01-01

    Plans for the nuclear start-up, low and high power physics testing, and core management of the Fast Test Reactor (FTR) are described. Owing to the arrangement of the fuel-handling system, which permits continuous instrument lead access to experiments during refuelling, it is most efficient to load the reactor in an asymmetric fashion, filling one-third core sectors at a time. The core neutron level will be monitored during this process using both in-core and ex-core detectors. A variety of physics tests are planned following the core loading. Because of the experimental purpose of the reactor, these tests will include a comprehensive characterization programme involving both active and passive neutron and gamma measurements. Following start-up tests, the FTR will be operated as a fast neutron irradiation facility, to test a wide variety of fast reactor core components and materials. Nuclear analyses will be made prior to each irradiation cycle to confirm that the planned arrangement of standard and experimental components satisfies all safety and operational constraints, and that all experiments are located so as to achieve their desired irradiation environment. (author)

  19. Installation of JMTR core management system

    International Nuclear Information System (INIS)

    Imaizumi, Tomomi; Ide, Hiroshi; Naka, Michihiro; Komukai, Bunsaku; Nagao, Yoshiharu

    2013-01-01

    In order to carry out the core management after the reoperation of JMTR quickly and accurately, the authors took up the Standard Reactor Analysis Code (SRAC) system and core management support programs that are operating in a general-purpose large computer and transferred them to PC (OS: Linux), and newly established a JMTR core management system. As for the core analysis, this measure enabled an increase in the processing speed from the check of core arrangement to the result display of nuclear restriction values to about 60 times, compared with the conventional method. It was confirmed that the differences of calculation results originated from the difference of internal display of computers, associated with the transfer of each analysis code from GS21-400 system to PC-Linux, were within practically allowable level. In the future, this system will be applied to the core analysis of JMTR, as well as to the preparation of operation plans. (A.O.)

  20. Retrospective study comparing six - and twelve-core prostate biopsy in detection of prostate cancer

    Directory of Open Access Journals (Sweden)

    Motoi Tobiume

    2008-02-01

    Full Text Available OBJECTIVE: We compared the safety and efficacy of the 12-core biopsy with those of the conventional systematic 6-core biopsy with PSA levels between 4.1 and 20.0 ng/mL. MATERIALS AND METHODS: This study included 428 patients who underwent a 6-core biopsy and 128 patients who underwent a 12-core biopsy. Biopsies were performed transrectally under ultrasound guidance. The 12-core biopsy scheme involved obtaining 6 far lateral cores. RESULTS: For patients with PSA level between 4.1 and 10.1 ng/mL, 47 of the 265 patients who underwent 6-core biopsy and 32 of the 91 patients who underwent a12-core biopsy were diagnosed with prostate cancer (p = 0.0006. Among the patients with a PSA level between 10.1 and 20.0 ng/mL, 48 of 163 patients who underwent the 6-core biopsy and 16 of 37 patients who underwent the 12-core biopsy were diagnosed with prostate cancer (p = 0.0606. Three of the 95 patients who were diagnosed with prostate cancer through the 6-core biopsy and 12 of the 48 patients who were diagnosed through the 12-core biopsy had cancer located in the anterior apex. The 12-core biopsy increased the diagnostic rate in the apex (p = 0.001. No statistically significant differences were found in incidence of complications. CONCLUSION: We concluded that the 12-core biopsy is a safe and more effective procedure for increasing the diagnostic rate of prostate cancer than the 6-core biopsy in patients with PSA level between 4.1 and 10.0 ng/mL, and the most useful anatomical area to be added was found to be cores from the anterior apex.

  1. Point-of-care diagnostics for niche applications.

    Science.gov (United States)

    Cummins, Brian M; Ligler, Frances S; Walker, Glenn M

    2016-01-01

    Point-of-care or point-of-use diagnostics are analytical devices that provide clinically relevant information without the need for a core clinical laboratory. In this review we define point-of-care diagnostics as portable versions of assays performed in a traditional clinical chemistry laboratory. This review discusses five areas relevant to human and animal health where increased attention could produce significant impact: veterinary medicine, space travel, sports medicine, emergency medicine, and operating room efficiency. For each of these areas, clinical need, available commercial products, and ongoing research into new devices are highlighted. Copyright © 2016 Elsevier Inc. All rights reserved.

  2. System theory in medical diagnostic devices: an overview.

    Science.gov (United States)

    Baura, Gail D

    2006-01-01

    Medical diagnostics refers to testing conducted either in vitro or in vivo to provide critical health care information for risk assessment, early diagnosis, treatment, or disease management. Typical in vivo diagnostic tests include the computed tomography scan, magnetic resonance imaging, and blood pressure screening. Typical in vitro diagnostic tests include cholesterol, Papanicolaou smear, and conventional glucose monitoring tests. Historically, devices associated with both types of diagnostics have used heuristic curve fitting during signal analysis. However, since the early 1990s, a few enterprising engineers and physicians have used system theory to improve their core processing for feature detection and system identification. Current applications include automated Pap smear screening for detection of cervical cancer and diagnosis of Alzheimer's disease. Future applications, such as disease prediction before symptom onset and drug treatment customization, have been catalyzed by the Human Genome Project.

  3. Is stereotactic large-core needle biopsy beneficial prior to surgical treatment in BI-RADS 5 lesions?

    NARCIS (Netherlands)

    Hoorntje, LE; Peeters, PHM; Mali, WPTM; Rinkes, IHMB

    Introduction. Due to screening mammography, more nonpalpable mammographic lesions warrant histological evaluation. Stereotactic large-core needle biopsy (SLCNB) has been shown to be as effective in diagnosing these lesions as diagnostic surgical excision, and has become the preferred diagnostic

  4. Development of in-core measuring method using optical techniques

    International Nuclear Information System (INIS)

    Kakuta, Tsunemi; Shikama, Tatsuo; Narui, Minoru; Sagawa, Tsutomu.

    1994-01-01

    Since applying to more severe radiation environments in nuclear plants, e.g., in-core measuring systems, diagnostics for fusion reactors, radiation related subjects should be considered by more severe radiation and environmental conditions. Owing to this, preliminary studies of heavy neutron irradiation effects on optical fibers are conducted in the core region of fission reactor. Two kinds of SiO 2 core optical fibers, highly pure SiO 2 with OH content core and SiO 2 with fluorine doped core, were irradiated in the core region of Japan Material Testing Reactor (JMTR). Both fibers were irradiated with fast neutron (E>1.0 MeV) fluence of about 1.6x10 19 n/cm 2 and gamma-ray doses of 3.3x10 9 Gy. The optical absorption and the light-emission spectrum were measured in-situ along the irradiation. This paper mainly outlines the fundamental effects of neutron irradiation and discuss the possibility of neutron detection in the core region of reactor. (J.P.N.)

  5. MCNPX simulations of fast neutron diagnostics for accelerator-driven systems

    Energy Technology Data Exchange (ETDEWEB)

    Habob, Moinul

    2005-12-15

    In accelerator-driven systems, the neutron spectrum will extend all the way up to the incident beam energy, i.e., several hundred MeV or even up to GeV energies. The high neutron energy allows novel diagnostics with a set of measurement techniques that can be used in a sub-critical reactor environment. Such measurements are primarily connected to system safety and validation. This report shows that in-core fast-neutron diagnostics can be employed to monitor changes in the position of incidence of the primary proton beam onto the neutron production target. It has also been shown that fast neutrons can be used to detect temperature-dependent density changes in a liquid lead-bismuth target. Fast neutrons can escape the system via the beam pipe for the incident proton beam. Out-of-core monitoring of these so called back-streaming neutrons could potentially be used to monitor beam changes if the target has a suitable shape. Moreover, diagnostics of back-streaming neutrons might be used for validation of the system design.

  6. MCNPX simulations of fast neutron diagnostics for accelerator-driven systems

    International Nuclear Information System (INIS)

    Habib, Moinul

    2005-12-01

    In accelerator-driven systems, the neutron spectrum will extend all the way up to the incident beam energy, i.e., several hundred MeV or even up to GeV energies. The high neutron energy allows novel diagnostics with a set of measurement techniques that can be used in a sub-critical reactor environment. Such measurements are primarily connected to system safety and validation. This report shows that in-core fast-neutron diagnostics can be employed to monitor changes in the position of incidence of the primary proton beam onto the neutron production target. It has also been shown that fast neutrons can be used to detect temperature-dependent density changes in a liquid lead-bismuth target. Fast neutrons can escape the system via the beam pipe for the incident proton beam. Out-of-core monitoring of these so called back-streaming neutrons could potentially be used to monitor beam changes if the target has a suitable shape. Moreover, diagnostics of back-streaming neutrons might be used for validation of the system design

  7. Status of ITER neutron diagnostic development

    Science.gov (United States)

    Krasilnikov, A. V.; Sasao, M.; Kaschuck, Yu. A.; Nishitani, T.; Batistoni, P.; Zaveryaev, V. S.; Popovichev, S.; Iguchi, T.; Jarvis, O. N.; Källne, J.; Fiore, C. L.; Roquemore, A. L.; Heidbrink, W. W.; Fisher, R.; Gorini, G.; Prosvirin, D. V.; Tsutskikh, A. Yu.; Donné, A. J. H.; Costley, A. E.; Walker, C. I.

    2005-12-01

    Due to the high neutron yield and the large plasma size many ITER plasma parameters such as fusion power, power density, ion temperature, fast ion energy and their spatial distributions in the plasma core can be measured well by various neutron diagnostics. Neutron diagnostic systems under consideration and development for ITER include radial and vertical neutron cameras (RNC and VNC), internal and external neutron flux monitors (NFMs), neutron activation systems and neutron spectrometers. The two-dimensional neutron source strength and spectral measurements can be provided by the combined RNC and VNC. The NFMs need to meet the ITER requirement of time-resolved measurements of the neutron source strength and can provide the signals necessary for real-time control of the ITER fusion power. Compact and high throughput neutron spectrometers are under development. A concept for the absolute calibration of neutron diagnostic systems is proposed. The development, testing in existing experiments and the engineering integration of all neutron diagnostic systems into ITER are in progress and the main results are presented.

  8. Status of ITER neutron diagnostic development

    International Nuclear Information System (INIS)

    Krasilnikov, A.V.; Sasao, M.; Kaschuck, Yu.A.; Nishitani, T.; Batistoni, P.; Zaveryaev, V.S.; Popovichev, S.; Iguchi, T.; Jarvis, O.N.; Kaellne, J.; Fiore, C.L.; Roquemore, A.L.; Heidbrink, W.W.; Fisher, R.; Gorini, G.; Prosvirin, D.V.; Tsutskikh, A.Yu.; Donne, A.J.H.; Costley, A.E.; Walker, C.I.

    2005-01-01

    Due to the high neutron yield and the large plasma size many ITER plasma parameters such as fusion power, power density, ion temperature, fast ion energy and their spatial distributions in the plasma core can be measured well by various neutron diagnostics. Neutron diagnostic systems under consideration and development for ITER include radial and vertical neutron cameras (RNC and VNC), internal and external neutron flux monitors (NFMs), neutron activation systems and neutron spectrometers. The two-dimensional neutron source strength and spectral measurements can be provided by the combined RNC and VNC. The NFMs need to meet the ITER requirement of time-resolved measurements of the neutron source strength and can provide the signals necessary for real-time control of the ITER fusion power. Compact and high throughput neutron spectrometers are under development. A concept for the absolute calibration of neutron diagnostic systems is proposed. The development, testing in existing experiments and the engineering integration of all neutron diagnostic systems into ITER are in progress and the main results are presented

  9. Status of ITER neutron diagnostic development

    International Nuclear Information System (INIS)

    Sasao, M.; Krasilnikov, A.V.; Kaschuck, Yu.A.; Nishitani, T.; Batistoni, P.; Zaveryaev, V.S.; Popovichev, S.; Jarvis, O.N.; Iguchi, T.; Kaellne, J.; Fiore, C.L.; Roquemore, A.L.; Heidbrink, W.W.; Fisher, R.; Gorini, G.; Donne, A.J.H.; Costley, A.E.; Walker, C.I.

    2005-01-01

    Due to the high neutron yield and the large plasma size many ITER plasma parameters such as fusion power, power density, ion temperature, fast ion energy and their spatial distributions in the plasma core can be well measured by various neutron diagnostics. Neutron diagnostic systems under consideration and development for ITER include: radial and vertical neutron cameras (RNC and VNC), internal and external neutron flux monitors, neutron activation systems and neutron spectrometers. The two-dimensional neutron source strength and spectral measurements can be provided by the combined RNC and VNC. The neutron flux monitors need to meet the ITER requirement of time-resolved measurements of the neutron source strength and can provide the signals necessary for real-time control of the ITER fusion power. Compact and high throughput neutron spectrometers are under development. A concept for the absolute calibration of neutron diagnostic systems is proposed. The development, testing in existing experiments and the engineering integration of all neutron diagnostic systems into ITER are in progress and the main results are presented. (author)

  10. The efficacy of an ultrasound-guided core needle biopsy with an 18G cutting needle for the diagnosis of pancreatic diseases

    International Nuclear Information System (INIS)

    Jung, Sung Hwa; Park, Won Kyu; Chang, Jay Chun; Kim, Jae Woon; Cho, Jae Ho; Jang, Han Won; Lee, Jae Kyo; Choi, Joon Hyuk

    2008-01-01

    The objective of this study is to evaluate the efficacy and safety of an ultrasound-guided core needle biopsy with an 18G cutting needle in patients suspected of having a pancreatic disease by analyzing the diagnostic performance and complication rate. The study population comprised 35 consecutive patients who underwent an ultrasound-guided core needle biopsy using a high-speed biopsy gun accompanied with an 18G cutting-type needle between May of 2001 and October of 2005. The diagnostic performance (i.e., the acquisition rate and diagnostic accuracy) and complications associated with core needle biopsies were evaluated for its efficacy and safety. Thirty-six sessions of ultrasound-guided core needle biopsies were performed in 35 consecutive patients. All patients, except two (serous cystadenoma and autoimmune pancreatitis) were diagnosed with various subtypes of pancreatic cancer. The acquisition rate and diagnostic accuracy were 97% (35/36) and 94% (34/36), respectively. A complication occurred only in one patient (3%), which further proved to be a delayed complication (i.e., needle tract implantation). According to our findings, the ultrasound-guided core needle biopsy is a viable and safe method for the diagnosis of pancreatic diseases. Moreover, it enables the diagnosis of the pancreatic cancer subtype

  11. Concordance between fine-needle aspiration and core biopsies for osseous lesions by lesion imaging appearance and CT attenuation.

    Science.gov (United States)

    Li, John; Weissberg, Zoe; Bevilacqua, Thomas A; Yu, Gordon; Weber, Kristy; Sebro, Ronnie

    2018-04-01

    To compare the concordance between fine-needle aspiration and core biopsies for osseous lesions by lesion imaging appearance and CT attenuation. Retrospective review of 215 FNAs of osseous lesions performed in conjunction with core biopsy at our institution over a 6-year period (2011-2016). FNAs were interpreted independently of core biopsies. We assessed if FNA in conjunction with core biopsy increased diagnostic accuracy compared to core biopsy alone. We also calculated the concordance between FNA and core biopsy by lesion appearance, lesion CT attenuation, lesion histology, lesion location and FNA needle gauge size. Core biopsy alone provided the diagnosis in 207/215 cases (96.3%), however, the FNA provided the diagnosis in the remaining 8/215 cases (3.7%) where the core biopsy was non-diagnostic. There were 154 (71.6%) lytic lesions, 21 (9.8%) blastic lesions, 25 (11.6%) mixed lytic and blastic lesions and 15 (7.0%) lesions that were neither lytic nor blastic. The concordance between FNA and core biopsy for lytic osseous lesions (136/154 cases, 88.3%) was statistically significantly higher than that for blastic osseous lesions (13/21 cases, 61.9%) [P = 4.2 × 10 -3 ; 95% CI (0.02, 0.50)]. The concordance between FNA and core biopsy was higher for low-attenuation- (110/126) than high-attenuation (58/77) lesions (P = 0.028). The concordance between FNA and core biopsy was also higher for metastases (102/119 cases, 85.7%) than non-metastases (78/96, 81.3%) [P = 0.487; 95% CI (- 0.15, 0.065)]. There was no difference in the rate of concordance between FNA and core biopsy by lesion location or FNA needle gauge size (P > 0.05). FNA with core biopsy increases diagnostic rate compared to core biopsy alone or FNA alone. The concordance between FNA and core biopsy is higher for lytic lesions than for blastic lesions; and higher for low-attenuation lesions than for high-attenuation lesions.

  12. Education plan

    International Nuclear Information System (INIS)

    Baur, J.

    1987-01-01

    There is pressing need for education of fusion people and those in the radiation effects community on the role of radiation hardening in radiation diagnostic. There is no plan at present to do this. The plan is to be proposed and developed. The education methods should include distribution of a primer, the proceedings of this workshop, and updated data compilations and talks by experts at the fusion labs, universities, and meetings

  13. Plan for shipment, storage, and examination of TMI-2 fuel

    International Nuclear Information System (INIS)

    Quinn, G.J.; Engen, I.A.; Tyacke, M.J.; Reno, H.W.

    1984-05-01

    This Plan addresses the preparation and shipment of core debris from Three Mile Island Unit 2 (TMI-2) to the Idaho National Engineering Laboratory (INEL) for receipt, storage, and examination. The Manager of the Nuclear Materials Evaluation Programs Division of EG and G Idaho, Inc. will manage two separate but integrated programs, one located at TMI (Part 1) and the other at INEL (Part 2). The Technical Integration Office (at TMI) is responsible for developing and implementing Part 1, TMI-2 Core Shipment Program. That portion of the Plan establishes coordination between TMI and INEL (and others) for shipment of core debris, and it provides the coordination by which handling systems at both locations are designed, constructed, or modified to establish and maintain system compatibility. The Technical Support Branch (at INEL) is responsible for developing and implementing Part 2, Core Activities Program. That portion of the Plan details operational and examination activities at INEL, as well as defines core-related activities planned at other DOE laboratories

  14. Establishment of computer aided technology for operation, maintenance, and core management

    International Nuclear Information System (INIS)

    Iguchi, Masaki; Isomura, Kazutoshi; Okawa, Tsuyoshi; Sakurai, Naoto

    2003-01-01

    In Fugen, the accumulated know-how of skilled operators, maintenance engineers, and core management engineers have been systematized by using the latest computer technology. These computerized systems have enhanced the technology of operating, maintenance and core management. This report describes the development of a reactor feed water control system with fuzzy logic, a refueling support system, and an automatic refueling planning system. Since operation of reactor feedwater control at low power requires a delicate operational technique and the knowledge and experience of operators, the application of a fuzzy algorithm was deemed effective in Fugen. Its good performance comparable to that of experienced operators can be realized. The fuel-handling operation takes proposed plans, fuel management and efficient operation by skilled operators. AI technology was applied to fuel-handling support system using past operation results and experience of skilled operators. This system is as capable of fuel-handling as skilled operators. Planning an adequate fuel loading pattern is time-consuming even for expert core management engineers. The Automatic Refueling Planning System (ARPS) was developed using Genetic Algorithms (GA) and a Simulated Annealing (SA). It has been verified that long-term fuel loading patterns of the Fugen NPS evaluated by ARPS are equivalent to that of an expert core management engineer. (author)

  15. TMI-2 Core Shipping Preparations

    International Nuclear Information System (INIS)

    Ball, L.J.; Barkanic, R.J.; Conaway, W.T. II; Schmoker, D. S.; Post, Roy G.

    1988-01-01

    Shipping the damaged core from the Unit 2 reactor of Three Mile Island Nuclear Power Station near Harrisburg, PA, to the Idaho National Engineering Laboratory near Idaho Falls, ID, required development and implementation of a completely new spent fuel transportation system. This paper describes of the equipment developed, the planning and activities used to implement the hard-ware-systems into the facilities, and the planning involved in making the rail shipments. It also includes a summary of recommendations resulting from this experience. (author)

  16. Surveillance test of the JMTR core components

    International Nuclear Information System (INIS)

    Takeda, Takashi; Amezawa, Hiroo; Tobita, Kenji

    1986-02-01

    Surveillance test for the core components of Japan Materials Testing Reactor (JMTR) was started in 1966, and completed in 1985 without one capsule. Most of capsules in the program, except one beryllium specimens, were removed from the core, and carred out the post-irradiation tests at the JMTR Hot Laboratory. The data is applied to review of JMTR core components management plan. JMTR surveillance test was carried out with several kind of materials of JMTR core components, Berylium as the reflector, Hafnium as the neutron absorber of control rod, 17-4PH stainless steel as a roller spring of the control rod, and 304 stainless steel as the grid plate. Results are described in this report. (author)

  17. Two dimensional radiated power diagnostics on Alcator C-Mod

    International Nuclear Information System (INIS)

    Reinke, M. L.; Hutchinson, I. H.

    2008-01-01

    The radiated power diagnostics for the Alcator C-Mod tokamak have been upgraded to measure two dimensional structure of the photon emissivity profile in order to investigate poloidal asymmetries in the core radiation. Commonly utilized unbiased absolute extreme ultraviolet (AXUV) diode arrays view the plasma along five different horizontal planes. The layout of the diagnostic set is shown and the results from calibrations and recent experiments are discussed. Data showing a significant, 30%-40%, inboard/outboard emissivity asymmetry during ELM-free H-mode are presented. The ability to use AXUV diode arrays to measure absolute radiated power is explored by comparing diode and resistive bolometer-based emissivity profiles for highly radiative L-mode plasmas seeded with argon. Emissivity profiles match in the core but disagree radially outward resulting in an underprediction of P rad of nearly 50% by the diodes compared to P rad determined using resistive bolometers.

  18. Two dimensional radiated power diagnostics on Alcator C-Moda)

    Science.gov (United States)

    Reinke, M. L.; Hutchinson, I. H.

    2008-10-01

    The radiated power diagnostics for the Alcator C-Mod tokamak have been upgraded to measure two dimensional structure of the photon emissivity profile in order to investigate poloidal asymmetries in the core radiation. Commonly utilized unbiased absolute extreme ultraviolet (AXUV) diode arrays view the plasma along five different horizontal planes. The layout of the diagnostic set is shown and the results from calibrations and recent experiments are discussed. Data showing a significant, 30%-40%, inboard/outboard emissivity asymmetry during ELM-free H-mode are presented. The ability to use AXUV diode arrays to measure absolute radiated power is explored by comparing diode and resistive bolometer-based emissivity profiles for highly radiative L-mode plasmas seeded with argon. Emissivity profiles match in the core but disagree radially outward resulting in an underprediction of Prad of nearly 50% by the diodes compared to Prad determined using resistive bolometers.

  19. Diagnostic radiology in the nearest future

    International Nuclear Information System (INIS)

    Lindenbraten, L.D.

    1984-01-01

    Basic trends of diagnostic radiology (DR) development in the nearest future are formulated. Possibilities of perspective ways and means of DR studies are described. The prohlems of strategy, tactics, organization of diagnostic radiological service are considered. An attempt has been made to outline the professional image of a specialist in the DR of the future. It is shown that prediction of the DR future development is the planning stage of the present, the choice of a right way of development

  20. Expert system for aiding fuel exchange planning

    International Nuclear Information System (INIS)

    Shiratori, Yoshitake.

    1992-01-01

    A fuel exchange plan is prepared based on intelligence bases such as a method of zoning a reactor core, a fuel arrangement rule and a procedure for fuel exchange, as well as initial data. Then, the fuel exchange plans are patterned to several groups based on the intelligence bases such as patterning of fuel arrangement. A typical pattern is analyzed by a reactor core analyzing code and allowance or rejection for the analyzed patterns is judged based on intelligence bases regarding life time of the reactor core, thermal limit value of fuels, burning of fuel for irradiation test. The result of the judgement is fed-back as an estimation information and the initial data and the intelligence data are added to prepare a plan again. A similar analysis is also conducted for the plan of the rejected group. The allowance or rejection is judged for all of the plans in the same manner. The intelligence bases are used and the result of the judgement is fed-back as a condition for estimation, thereby enabling to remarkably save labors and time and prepare non-typical exchange plans. (N.H.)

  1. Ra reactor operation plan for 1976 - Annex 6

    International Nuclear Information System (INIS)

    Martinc, R.

    1976-01-01

    Contrary to previous years the RA reactor operation plan for 1976 is conditioned by more uncertainties than ever for the following reasons. It is planned for February to repair the components in order to eliminate the consequences of leaking from the vertical experimental channel VK-4 which happened in december 1975. Apart from this, measurements related to transfer of the core to highly enriched fuel under minimum power are foreseen to be performed in February. In April, it would be indispensable to locate the point of He gas leaking and its prevention. Core transfer to highly enriched fuel is planned for April for testing of the fuel elements under operating conditions and step by step increase of the power density up to the nominal power. Complete plan for core transfer would be available by the end of February 1976. It is planned to make-up for the mentioned delays from May-December 1976 [sr

  2. Ultrasound-guided percutaneous core needle biopsy of splenic lesions

    Energy Technology Data Exchange (ETDEWEB)

    Park, SangIk; Shin, Yong Moon; Won, Hyung Jin; Kim, Pyo Nyun; Lee, Moon Gyu [Dept. of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul (Korea, Republic of)

    2017-05-15

    To evaluate the safety and efficacy of ultrasound-guided percutaneous core needle biopsy of splenic lesions. This retrospective study included 30 patients who underwent percutaneous core needle biopsy of their splenic lesions using 18- or 20-gauge needles between January 2001 and July 2016 in a single tertiary care center. The characteristics of the splenic lesions were determined by reviewing the ultrasound and computed tomography examinations. Acquisition rate and diagnostic accuracy were calculated, using pathologic results of the splenectomy specimen, clinical course and/or imaging follow-up as a reference standard. Post-procedure complications were identified from electronic medical records, laboratory findings and computed tomography images. Seventy-three specimens were obtained from the 30 patients and splenectomy was performed in 2 patients. Twenty-nine of the 30 patients had focal splenic lesions, while the remaining patient had homogeneous splenomegaly. Acquisition rate and diagnostic accuracy were 80.0% (24/30) and 76.7% (23/30), respectively. Perisplenic hemorrhage without hemodynamic instability developed in one patient. Ultrasound-guided percutaneous core needle biopsy of splenic lesions is a safe method for achieving a histopathologic diagnosis and can be considered as an alternative to splenectomy in patients with a high risk of splenectomy-related complications.

  3. Ultrasound-guided percutaneous core needle biopsy of splenic lesions

    International Nuclear Information System (INIS)

    Park, SangIk; Shin, Yong Moon; Won, Hyung Jin; Kim, Pyo Nyun; Lee, Moon Gyu

    2017-01-01

    To evaluate the safety and efficacy of ultrasound-guided percutaneous core needle biopsy of splenic lesions. This retrospective study included 30 patients who underwent percutaneous core needle biopsy of their splenic lesions using 18- or 20-gauge needles between January 2001 and July 2016 in a single tertiary care center. The characteristics of the splenic lesions were determined by reviewing the ultrasound and computed tomography examinations. Acquisition rate and diagnostic accuracy were calculated, using pathologic results of the splenectomy specimen, clinical course and/or imaging follow-up as a reference standard. Post-procedure complications were identified from electronic medical records, laboratory findings and computed tomography images. Seventy-three specimens were obtained from the 30 patients and splenectomy was performed in 2 patients. Twenty-nine of the 30 patients had focal splenic lesions, while the remaining patient had homogeneous splenomegaly. Acquisition rate and diagnostic accuracy were 80.0% (24/30) and 76.7% (23/30), respectively. Perisplenic hemorrhage without hemodynamic instability developed in one patient. Ultrasound-guided percutaneous core needle biopsy of splenic lesions is a safe method for achieving a histopathologic diagnosis and can be considered as an alternative to splenectomy in patients with a high risk of splenectomy-related complications

  4. A Common Definition of the System Operators' Core Activities

    International Nuclear Information System (INIS)

    2006-02-01

    In this report a common definition of the system operator's core activities in the Nordic countries is identified and also a list of non-core activities is introduced. As a starting point the common tasks for system responsibility as identified by Nordel has been used for the work. The term TSO (Transmission System Operator) is employed as a common denominator in the report. It is found out that the TSOs carry out common core activities in the roles as a transmission operator, a system operator and a balance settlement responsible. The core activities for the TSO as a transmission network operator are: Maintain the adequate transmission system in the long run and network development plan on the national as well as on the Nordic level using sophisticated analysis and planning methods and tools. Plan the transmission network on the national as well as on the Nordic level utilising new investments, renewal and maintenance of existing network components so that the network is secure to operate and adequate transmission capacity is guaranteed. Aim at timely network expansions using enhanced information exchange between the Nordic TSOs, and on the national level between the TSO and distribution and regional network operators, large consumers and large producers. Secure the technical compatibility with networks across the border and within a country by establishing connection requirements on the national level and ensuring that the national requirements are compatible across the Nordic power system. The core activities for the TSO as a system operator are: Define common technical requirements for the secure system operation using common planning, operation, connection and data exchange procedures. Secure the system operation with the operational planning for the following year by using information exchange between TSOs enabling the TSOs to make the best possible forecast of the global grid situation in order to assess the flows in their network and the available

  5. A retrospective analysis of ultrasound-guided large core needle ...

    African Journals Online (AJOL)

    A retrospective analysis of ultrasound-guided large core needle biopsies of breast lesions at a regional public hospital in Durban, KwaZulu-Natal, South Africa. ... Objective: To assess the influence of technical variables on the diagnostic yield of breast specimens obtained by using US-LCNB, and the sensitivity of detecting ...

  6. Overview of ion source characterization diagnostics in INTF

    Science.gov (United States)

    Bandyopadhyay, M.; Sudhir, Dass; Bhuyan, M.; Soni, J.; Tyagi, H.; Joshi, J.; Yadav, A.; Rotti, C.; Parmar, Deepak; Patel, H.; Pillai, S.; Chakraborty, A.

    2016-02-01

    INdian Test Facility (INTF) is envisaged to characterize ITER diagnostic neutral beam system and to establish the functionality of its eight inductively coupled RF plasma driver based negative hydrogen ion source and its beamline components. The beam quality mainly depends on the ion source performance and therefore, its diagnostics plays an important role for its safe and optimized operation. A number of diagnostics are planned in INTF to characterize the ion source performance. Negative ions and its cesium contents in the source will be monitored by optical emission spectroscopy (OES) and cavity ring down spectroscopy. Plasma near the extraction region will be studied using standard electrostatic probes. The beam divergence and negative ion stripping losses are planned to be measured using Doppler shift spectroscopy. During initial phase of ion beam characterization, carbon fiber composite based infrared imaging diagnostics will be used. Safe operation of the beam will be ensured by using standard thermocouples and electrical voltage-current measurement sensors. A novel concept, based on plasma density dependent plasma impedance measurement using RF electrical impedance matching parameters to characterize the RF driver plasma, will be tested in INTF and will be validated with OES data. The paper will discuss about the overview of the complete INTF diagnostics including its present status of procurement, experimentation, interface with mechanical systems in INTF, and integration with INTF data acquisition and control systems.

  7. Application of digital diagnostic impression, virtual planning, and computer-guided implant surgery for a CAD/CAM-fabricated, implant-supported fixed dental prosthesis: a clinical report.

    Science.gov (United States)

    Stapleton, Brandon M; Lin, Wei-Shao; Ntounis, Athanasios; Harris, Bryan T; Morton, Dean

    2014-09-01

    This clinical report demonstrated the use of an implant-supported fixed dental prosthesis fabricated with a contemporary digital approach. The digital diagnostic data acquisition was completed with a digital diagnostic impression with an intraoral scanner and cone-beam computed tomography with a prefabricated universal radiographic template to design a virtual prosthetically driven implant surgical plan. A surgical template fabricated with computer-aided design and computer-aided manufacturing (CAD/CAM) was used to perform computer-guided implant surgery. The definitive digital data were then used to design the definitive CAD/CAM-fabricated fixed dental prosthesis. Copyright © 2014 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.

  8. Core concepts of spatial prioritisation in systematic conservation planning.

    Science.gov (United States)

    Kukkala, Aija S; Moilanen, Atte

    2013-05-01

    Systematic conservation planning (SCP) is a field of conservation biology concerned with delivering on-the-ground actions that achieve conservation goals. It describes a set of operational models that cover both design and implementation of conservation, with a strong focus on mobilising the collective action typically required to implement conservation. SCP, as it was originally described, was composed of six different stages: collection of data, identification of conservation goals, evaluation of the existing protected area network, design of expansions, implementation of conservation action, and long-term maintenance of biodiversity in the network. Since then, the operational model has been expanded into several different variants. Conservation actions applied inside SCP include establishment and expansion of reserve networks and allocation of habitat restoration and management. Within the broader context of SCP, there is a fundamental biogeographic-economic analysis frequently called spatial conservation prioritisation or conservation assessment, which is used for identifying where important areas for biodiversity are and how conservation goals might be achieved efficiently. Here, we review the usage and meaning of the 12 biogeographic-economic core concepts of SCP: adequacy, complementarity, comprehensiveness, effectiveness, efficiency, flexibility, irreplaceability, replacement cost, representation, representativeness, threat, and vulnerability. Some of the concepts have clear definitions whereas others may have alternative and possibly conflicting definitions. With a comprehensive literature review literature, we elucidate the historical backgrounds of these concepts, the first definitions and usages, alternative later definitions, key applications, and prior reviews. This review reduces linguistic uncertainty in the application of SCP. Since SCP is a global activity with a multitude of different stakeholders involved, it is vital that those involved can

  9. The role of neural networks in reactor diagnostics and control

    International Nuclear Information System (INIS)

    Pazsit, I.; Kitamura, M.

    1997-01-01

    Reactor diagnostics and core diagnostics in particular, is an inverse task, just as most other diagnostics. One measures some physical parameter at some position, or the fluctuation thereof, which is given rise by the fluctuation of another parameter, presumably at a different position. In neutron noise diagnostics, the measured quantity is the neutron noise, whereas the cause, fluctuations of the core material, is called the open-quotes noise sourceclose quotes. The relationship between the cause (noise source) and the induced noise (effect) is determined by the physics of the process and can usually be described by a theory. This means that the direct task, calculation of the noise from the noise source, can always be achieved. In diagnostics, however, the process starts from the back end, i.e. one observes the effect of some cause. The task is to infer the cause (noise source) from the effect (induced noise), which is an inverse task (sometimes also called unfolding). The situation is very much similar even regarding control problems. The system state is described by a vector in the parameter space. When it deviates from the desired one, the control parameters need to be changed to bring the system into the desired state. The computation of the change in the state vector, due to a change in the control vector, can be calculated with no difficulty in principle. The control requires however the inverse task to be performed, i.e. to determine which changes of the control vector would bring the state vector into the desired state

  10. Diagnostics for PLX-alpha

    Science.gov (United States)

    Gilmore, Mark; Hsu, Scott

    2015-11-01

    The goal of the Plasma Liner eXperiment PLX-alpha at Los Alamos National Laboratory is to establish the viability of creating a spherically imploding plasma liner for MIF and HED applications, using a spherical array of supersonic plasma jets launched by innovative contoured-gap coaxial plasma guns. PLX- α experiments will focus in particular on establishing the ram pressure and uniformity scalings of partial and fully spherical plasma liners. In order to characterize these parameters experimentally, a suite of diagnostics is planned, including multi-camera fast imaging, a 16-channel visible interferometer (upgraded from 8 channels) with reconfigurable, fiber-coupled front end, and visible and VUV high-resolution and survey spectroscopy. Tomographic reconstruction and data fusion techniques will be used in conjunction with interferometry, imaging, and synthetic diagnostics from modeling to characterize liner uniformity in 3D. Diagnostic and data analysis design, implementation, and status will be presented. Supported by the Advanced Research Projects Agency - Energy - U.S. Department of Energy.

  11. Pacific Northwest National Laboratory institutional plan: FY 1996--2001

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-01-01

    This report contains the operation and direction plan for the Pacific Northwest National Laboratory of the US Department of Energy. The topics of the plan include the laboratory mission and core competencies, the laboratory strategic plan; the laboratory initiatives in molecular sciences, microbial biotechnology, global environmental change, complex modeling of physical systems, advanced processing technology, energy technology development, and medical technologies and systems; core business areas, critical success factors, and resource projections.

  12. Evidence for the diagnostic criteria of delirium: an update.

    Science.gov (United States)

    Blazer, Dan G; van Nieuwenhuizen, Adrienne O

    2012-05-01

    Since the publication of DSM-III in 1980, the essential criteria for delirium have been reduced progressively through DSM-III-R to DSM-IV. As the field moves toward DSM-V and ICD-11, new data can shed light on the nosological changes that are needed so that diagnostic criteria can reflect empirical data. In this study, we reassess the existing or potential criteria for delirium. Phenomenological studies in recent years have informed the criteria for delirium, including the appropriateness of the term 'consciousness' as a core symptom of the diagnosis, additional symptoms of delirium that are frequent but are not currently part of the diagnostic criteria, subsyndromal delirium, motoric subtypes of delirium (hyperactive, hypoactive), and the association of delirium with dementia. Recent studies suggest that motoric subtypes should be included as a subtype for delirium but that subsyndromal delirium, although a useful research construct, should not be included in clinical diagnostic criteria given the frequent fluctuation in symptoms over short periods. In addition, though the core symptoms are probably adequate to make the diagnosis, clinicians must be aware of the frequency of other symptoms, for symptoms such as profound sleep disturbance or psychotic symptoms may dominate the clinical picture.

  13. Fuzzy based method for project planning of the infrastructure design for the diagnostic in ITER

    International Nuclear Information System (INIS)

    Piros, Attila; Veres, Gábor

    2013-01-01

    The long-term design projects need special preparation before the start of the execution. This preparation usually includes the drawing of the network diagram for the whole procedure. This diagram includes the time estimation of the individual subtasks and gives us information about the predicted dates of the milestones. The calculated critical path in this network characterizes a specific design project concerning to its duration very well. Several methods are available to support this step of preparation. This paper describes a new method to map the structure of the design process and clarify the milestones and predict the dates of these milestones. The method is based on the PERT (Project Evaluation and Review Technique) network but as a novelty it applies fuzzy logic to find out the concerning times in this graph. With the application of the fuzzy logic the handling of the different kinds of design uncertainties becomes feasible. Many kinds of design uncertainties exist from the possible electric blackout up to the illness of an engineer. In many cases these uncertainties are related with human errors and described with linguistic expressions. The fuzzy logic enables to transform these ambiguous expressions into numeric values for further mathematical evaluation. The method is introduced in the planning of the design project of the infrastructure for the diagnostic systems of ITER. The method not only helps the project in the planning phase, but it will be a powerful tool in mathematical modeling and monitoring of the project execution

  14. Fuzzy based method for project planning of the infrastructure design for the diagnostic in ITER

    Energy Technology Data Exchange (ETDEWEB)

    Piros, Attila, E-mail: attila.piros@gt3.bme.hu [Department of Machine and Product Design, Budapest University of Technology and Economics, Budapest (Hungary); Veres, Gábor [Department of Plasma Physics, Wigner Research Centre for Physics, Hungarian Academy of Sciences, Budapest (Hungary)

    2013-10-15

    The long-term design projects need special preparation before the start of the execution. This preparation usually includes the drawing of the network diagram for the whole procedure. This diagram includes the time estimation of the individual subtasks and gives us information about the predicted dates of the milestones. The calculated critical path in this network characterizes a specific design project concerning to its duration very well. Several methods are available to support this step of preparation. This paper describes a new method to map the structure of the design process and clarify the milestones and predict the dates of these milestones. The method is based on the PERT (Project Evaluation and Review Technique) network but as a novelty it applies fuzzy logic to find out the concerning times in this graph. With the application of the fuzzy logic the handling of the different kinds of design uncertainties becomes feasible. Many kinds of design uncertainties exist from the possible electric blackout up to the illness of an engineer. In many cases these uncertainties are related with human errors and described with linguistic expressions. The fuzzy logic enables to transform these ambiguous expressions into numeric values for further mathematical evaluation. The method is introduced in the planning of the design project of the infrastructure for the diagnostic systems of ITER. The method not only helps the project in the planning phase, but it will be a powerful tool in mathematical modeling and monitoring of the project execution.

  15. 9 CFR 147.8 - Procedures for preparing egg yolk samples for diagnostic tests.

    Science.gov (United States)

    2010-01-01

    ... samples for diagnostic tests. 147.8 Section 147.8 Animals and Animal Products ANIMAL AND PLANT HEALTH... IMPROVEMENT PLAN Blood Testing Procedures § 147.8 Procedures for preparing egg yolk samples for diagnostic... for diagnostic testing. (b) The authorized laboratory must identify each egg as to the breeding flock...

  16. HYDRATE CORE DRILLING TESTS

    Energy Technology Data Exchange (ETDEWEB)

    John H. Cohen; Thomas E. Williams; Ali G. Kadaster; Bill V. Liddell

    2002-11-01

    The ''Methane Hydrate Production from Alaskan Permafrost'' project is a three-year endeavor being conducted by Maurer Technology Inc. (MTI), Noble, and Anadarko Petroleum, in partnership with the U.S. DOE National Energy Technology Laboratory (NETL). The project's goal is to build on previous and ongoing R&D in the area of onshore hydrate deposition. The project team plans to design and implement a program to safely and economically drill, core and produce gas from arctic hydrates. The current work scope includes drilling and coring one well on Anadarko leases in FY 2003 during the winter drilling season. A specially built on-site core analysis laboratory will be used to determine some of the physical characteristics of the hydrates and surrounding rock. Prior to going to the field, the project team designed and conducted a controlled series of coring tests for simulating coring of hydrate formations. A variety of equipment and procedures were tested and modified to develop a practical solution for this special application. This Topical Report summarizes these coring tests. A special facility was designed and installed at MTI's Drilling Research Center (DRC) in Houston and used to conduct coring tests. Equipment and procedures were tested by cutting cores from frozen mixtures of sand and water supported by casing and designed to simulate hydrate formations. Tests were conducted with chilled drilling fluids. Tests showed that frozen core can be washed out and reduced in size by the action of the drilling fluid. Washing of the core by the drilling fluid caused a reduction in core diameter, making core recovery very difficult (if not impossible). One successful solution was to drill the last 6 inches of core dry (without fluid circulation). These tests demonstrated that it will be difficult to capture core when drilling in permafrost or hydrates without implementing certain safeguards. Among the coring tests was a simulated hydrate

  17. [Use of diagnostic templates at stages of prosthetics treatment with implant-retained restorations].

    Science.gov (United States)

    Gvetadze, R Sh; Abramyan, S V; Ivanov, A A; Nubaryan, A P

    The comparative analysis of efficiency of various types of diagnostic templates for planning orthopedic treatment of 50 patients with partial or complete absence of teeth was performed. The patients were divided in 3 groups according to template manufacturing technique. All diagnostic templates made in accordance with clinical conditions allowed transfering digital data of the scheduled prosthetic construction for virtual implantation planning. Advantages and pitfalls of each template type are discussed.

  18. Accuracy of CT-guided percutaneous core needle biopsy for assessment of pediatric musculoskeletal lesions

    International Nuclear Information System (INIS)

    Hryhorczuk, Anastasia L.; Strouse, Peter J.; Biermann, J.S.

    2011-01-01

    CT-guided percutaneous core needle biopsy has been shown in adults to be an effective diagnostic tool for a large number of musculoskeletal malignancies. To characterize our experience with CT-guided percutaneous core needle biopsy of pediatric bone lesions and determine its utility in diagnosing pediatric osseous lesions, in a population where such lesions are commonly benign. From 2000 to 2009, 61 children underwent 63 CT-guided percutaneous biopsies. Radiological, pathological and clinical records were reviewed. Fourteen biopsies (22%) were performed on malignant lesions, while 49 biopsies (78%) were performed on benign lesions. Forty-nine of the 63 biopsies (78%) were adequate; these children underwent no further tissue sampling. Fourteen of the 63 biopsies (22%) were inadequate or non-conclusive. Of these patients, 12 underwent open biopsy. Retrospective analysis of percutaneous biopsies in these patients demonstrates that 9/12 provided clinically relevant information, and 4/12 patients received final diagnoses that confirmed initial core biopsy findings. No malignancies were diagnosed as benign on percutaneous biopsy. Overall, percutaneous core needle biopsy provided accurate diagnostic information in 84% (53/63) of biopsies. Our results demonstrate that CT-guided percutaneous biopsy is safe and beneficial in children. This study supports the use of CT-guided percutaneous core needle biopsy for primary diagnosis of pediatric bone lesions. (orig.)

  19. Cylindrical core reflood test facility (CCTF) and slab core reflood test facility (SCTF) for Japan Atomic Energy Research Institute (JAERI)

    International Nuclear Information System (INIS)

    1981-01-01

    IHI has designed and constructed the CCTF at JAERI to be used in the safety analysis research on the loss of coolant accident in a PWR plant. This test facility is planned so that reflood phenomenon in the PWR plant (a phenomenon is that the bared and overheated core is reflooded by the emergency core cooling system when the coolant loss accident occurred) is simulated under various test conditions. The CCTF is the largest-scale test plant in the world, composed of approximately 2000 simulated fuel rods (electric heaters), 1 simulated pressure vessel, 4 primary cooling loops, 2 simulated steam generators, emergency core cooling system, and so on. The test conditions are controlled, and the test steps are sequentially progressed by the computing system, and test data are collected by the data acquisition system. Furthermore, IHI is now designing and constructing the SCTF in accordance with the JAERI research plan. The SCTF is similar to the CCTF in scale. Main feature of the SCTF is the form of the simulated core and the simulated pressure vessel, which is of slab construction to be representative of the radial section of the PWR reactor. Reliable and various data for safety analysis are expected by the CCTF and the SCTF. (author)

  20. WCRP COordinated Regional Downscaling EXperiment (CORDEX: a diagnostic MIP for CMIP6

    Directory of Open Access Journals (Sweden)

    W. J. Gutowski Jr.

    2016-11-01

    Full Text Available The COordinated Regional Downscaling EXperiment (CORDEX is a diagnostic model intercomparison project (MIP in CMIP6. CORDEX builds on a foundation of previous downscaling intercomparison projects to provide a common framework for downscaling activities around the world. The CORDEX Regional Challenges provide a focus for downscaling research and a basis for making use of CMIP6 global climate model (GCM output to produce downscaled projected changes in regional climates and assess sources of uncertainties in the projections, all of which can potentially be distilled into climate change information for vulnerability, impacts and adaptation studies. CORDEX Flagship Pilot Studies advance regional downscaling by targeting one or more of the CORDEX Regional Challenges. A CORDEX-CORE framework is planned that will produce a baseline set of homogeneous high-resolution, downscaled projections for regions worldwide. In CMIP6, CORDEX coordinates with ScenarioMIP and is structured to allow cross comparisons with HighResMIP and interaction with the CMIP6 VIACS Advisory Board.

  1. Core monitoring with analytical model adaption

    International Nuclear Information System (INIS)

    Linford, R.B.; Martin, C.L.; Parkos, G.R.; Rahnema, F.; Williams, R.D.

    1992-01-01

    The monitoring of BWR cores has evolved rapidly due to more capable computer systems, improved analytical models and new types of core instrumentation. Coupling of first principles diffusion theory models such as applied to design to the core instrumentation has been achieved by GE with an adaptive methodology in the 3D Minicore system. The adaptive methods allow definition of 'leakage parameters' which are incorporated directly into the diffusion models to enhance monitoring accuracy and predictions. These improved models for core monitoring allow for substitution of traversing in-core probe (TIP) and local power range monitor (LPRM) with calculations to continue monitoring with no loss of accuracy or reduction of thermal limits. Experience in small BWR cores has shown that with one out of three TIP machines failed there was no operating limitation or impact from the substitute calculations. Other capabilities exist in 3D Monicore to align TIPs more accurately and accommodate other types of system measurements or anomalies. 3D Monicore also includes an accurate predictive capability which uses the adaptive results from previous monitoring calculations and is used to plan and optimize reactor maneuvers/operations to improve operating efficiency and reduce support requirements

  2. Developmentally sensitive diagnostic criteria for mental health disorders in early childhood: the diagnostic and statistical manual of mental disorders-IV, the research diagnostic criteria-preschool age, and the diagnostic classification of mental health and developmental disorders of infancy and early childhood-revised.

    Science.gov (United States)

    Egger, Helen L; Emde, Robert N

    2011-01-01

    As the infant mental health field has turned its focus to the presentation, course, and treatment of clinically significant mental health disorders, the need for reliable and valid criteria for identifying and assessing mental health symptoms and disorders in early childhood has become urgent. In this article we offer a critical perspective on diagnostic classification of mental health disorders in young children. We place the issue of early childhood diagnosis within the context of classification of psychopathology at other ages and describe, in some detail, diagnostic classifications that have been developed specifically for young children, including the Diagnostic Classification of Mental Health and Developmental Disorders of Infancy and Early Childhood (DC:0-3R; ZERO TO THREE, 2005), a diagnostic classification for mental health symptoms and disorders in infants, toddlers, and preschoolers. We briefly outline the role of diagnostic classification in clinical assessment and treatment planning. Last, we review the limitations of current approaches to the diagnostic classification of mental health disorders in young children. PsycINFO Database Record (c) 2010 APA, all rights reserved.

  3. Fine-needle versus core-needle biopsy – which one to choose in preoperative assessment of focal lesions in the breasts? Literature review

    Directory of Open Access Journals (Sweden)

    Ewa Łukasiewicz

    2017-12-01

    Full Text Available Aim: The aim of the study was to review two techniques that can be used to verify focal lesions in the breasts: fine-needle aspiration biopsy and core-needle biopsy. Material and methods: Fifty-five articles (original papers and reviews, half of them published within the past 5 years, were included in the analysis. The authors also took their own experience into account. Results: Pre-operative assessment of focal lesions in the breasts is crucial in the planning of further therapeutic management. The role of fine-needle aspiration biopsy has been reduced lately due to its low sensitivity and specificity as well as a high rate of non-diagnostic, suspicious and false negative results. This method does not enable one to differentiate between in situ and invasive disease. Currently, fine-needle biopsy is recommended for cystic lesions, suspected of being recurrences in the chest wall, and lymph node metastases. Core-needle biopsy is the basic diagnostic method of breast lesions. According to the recommendations of the Polish Ultrasound Society and American College of Radiology, BIRADS 4 and 5 lesions should be evaluated histopathologically. Core-needle biopsy makes it possible to establish a final diagnosis more frequently than fine-needle biopsy, both in the case of benign and malignant lesions. It delivers more information about the nature of a tumor (mutation of HER-2, estrogen and progesterone receptors and Ki-67 index. Its limitations include: underestimation of invasion and failure to recognize the components of ductal carcinoma in situ in papillary and atypical lesions. Single fine-needle aspiration biopsy is inexpensive, but when considering the cost of further diagnosis due to non-diagnostic, suspicious and atypical results, this method generates high additional costs. Conclusions: Microscopic verification of focal breast lesions is crucial for further therapeutic decisions. It has been proven that histopathological verification is more

  4. Use and evaluation of molecular diagnostics for pneumonia etiology studies

    NARCIS (Netherlands)

    Bhat, Niranjan; O'Brien, Katherine L.; Karron, Ruth A.; Driscoll, Amanda J.; Murdoch, David R.; Black, Robert E.; Bhutta, Zulfiqar A.; Campbell, Harry; Cherian, Thomas; Crook, Derrick W.; de Jong, Menno D.; Dowell, Scott F.; Graham, Stephen M.; Klugman, Keith P.; Lanata, Claudio F.; Madhi, Shabir A.; Martin, Paul; Nataro, James P.; Piazza, Franco M.; Qazi, Shamim A.; Zar, Heather J.

    2012-01-01

    Comprehensive microbiological testing will be a core function of the Pneumonia Etiology Research for Child Health (PERCH) project. The development stage of PERCH provided the time and resources necessary for us to conduct a comprehensive review of the current state of respiratory diagnostics. These

  5. 216-Day report for Tank 241-C-111, cores 58 and 59

    International Nuclear Information System (INIS)

    Rice, A.D.

    1994-01-01

    Three core samples from tank C-111, and a field blank, were received by the 222-S laboratories. Cores 58, 59, and the field blank were analyzed in accordance with plans. A hot cell blank was analyzed at the direction of the hot cell chemist. No sample results exceeded the notification limits. Core 60 was not analyzed

  6. An edge over diagnostic setup

    Directory of Open Access Journals (Sweden)

    Sridhar Kannan

    2017-01-01

    Full Text Available Diagnostic setup proposed by H.D. Kingsley serves as a practical aid in treatment planning and diagnosis. These setups have some inherent shortcomings. A simple technique of duplication of the setups in dental stone can solve problems encountered before as well as provide many other advantages over the conventional procedure. The diagnostic setup is prepared by the conventional method [Figure 1]. An alginate impression is then taken of the setups and poured in dental stone to obtain the derived treatment model [Figure 2]. The same setup can now be further modified for alternate lines of treatment. Subsequently models could then be obtained as required [Figure 3].

  7. Does MR imaging effectively replace diagnostic arthroscopy

    International Nuclear Information System (INIS)

    Ruwe, P.; McCarthy, S.; Wright, J.; Randall, L.; Lynch, K.; Jokyl, P.

    1990-01-01

    This paper determines if MR imaging reduces the number of diagnostic arthroscopic procedures required in patients with knee complaints and if MR imaging is cost-effective compared with diagnostic arthroscopy. The cohort analysis consists of 100 patients seen in a sports medicine clinic by two orthopedic surgeons who agreed on well-defined criteria for performing MR imaging and arthroscopy. Each orthopedic surgeon referring a patient for MR imaging checked a form regarding the plans for arthroscopy. Outcome analysis was conducted at 6 months

  8. TMI-2 core-examination program: INEL facilities readiness study

    International Nuclear Information System (INIS)

    McLaughlin, T.B.

    1983-02-01

    This report reviews the capability and readiness of remote handling facilities at the Idaho National Engineering Laboratory (INEL) to receive, and store the TMI-2 core, and to examine and analyze TMI-2 core samples. To accomplish these objectives, the facilities must be able to receive commercial casks, unload canisters from the casks, store the canisters, open the canisters, handle the fuel debris and assemblies, and perform various examinations. The report identifies documentation, including core information, necessary to INEL before receiving the entire TMI-2 core. Also identified are prerequisites to INEL's receipt of the first canister: costs, schedules, and a preliminary project plan for the tasks

  9. A review of the core catcher design in LMR

    International Nuclear Information System (INIS)

    Lee, Yong Bum; Hahn, Do Hee

    2001-08-01

    The overwhelming emphasis in reactor safety is on the prevention of core meltdown. Moreover, although there have been several accidents that have resulted in some fuel melting, to date there have been no accidents severe enough to cause the syndrome of core collapse, reactor vessel melt-through, containment penetration, and dispersal into the ground. Nevertheless, a number of proposals have been made for the design of core catcher systems to control or stop the motion of the molten core mass should such an accident take place. Core catchers may differ in both their location within the reactor system and in the mechanism that is used to cool and control the motion of the core debris. In this report the classification, configuration and main features of the core catcher are described. And also, The core catcher design technologies and processes are presented. Finally the core catcher provisions in constructed and planned LMRs (Liquid Metal Reactors) are summarized and the preliminary assessment on the core catcher installation in KALIMER is presented

  10. 40 CFR 35.6225 - Activities eligible for funding under Core Program Cooperative Agreements.

    Science.gov (United States)

    2010-07-01

    ... under a Core Program Cooperative Agreement, activities must develop and maintain a recipient's abilities... safety plans, quality assurance project plans, and community relation plans); (2) Provisions for... staff to manage publicly-funded cleanups, oversee responsible party-lead cleanups, and provide clerical...

  11. Lanczos Tridiagonalization and Core Problems

    Czech Academy of Sciences Publication Activity Database

    Hnětynková, Iveta; Strakoš, Zdeněk

    2007-01-01

    Roč. 421, č. 2-3 (2007), s. 243-251 ISSN 0024-3795 R&D Projects: GA AV ČR 1ET400300415 Institutional research plan: CEZ:AV0Z10300504 Keywords : linear approximation problem * orthogonal transformation * core problem * Golub-Kahan bidiagonalization * Lanczos tridiagonalization * Jacobi matrix Subject RIV: BA - General Mathematics Impact factor: 0.702, year: 2007

  12. Dislocation core structures in Si-doped GaN

    International Nuclear Information System (INIS)

    Rhode, S. L.; Fu, W. Y.; Sahonta, S.-L.; Kappers, M. J.; Humphreys, C. J.; Horton, M. K.; Pennycook, T. J.; Dusane, R. O.; Moram, M. A.

    2015-01-01

    Aberration-corrected scanning transmission electron microscopy was used to investigate the core structures of threading dislocations in plan-view geometry of GaN films with a range of Si-doping levels and dislocation densities ranging between (5 ± 1) × 10 8  and (10 ± 1) × 10 9  cm −2 . All a-type (edge) dislocation core structures in all samples formed 5/7-atom ring core structures, whereas all (a + c)-type (mixed) dislocations formed either double 5/6-atom, dissociated 7/4/8/4/9-atom, or dissociated 7/4/8/4/8/4/9-atom core structures. This shows that Si-doping does not affect threading dislocation core structures in GaN. However, electron beam damage at 300 keV produces 4-atom ring structures for (a + c)-type cores in Si-doped GaN

  13. Dislocation core structures in Si-doped GaN

    Energy Technology Data Exchange (ETDEWEB)

    Rhode, S. L., E-mail: srhode@imperial.ac.uk; Fu, W. Y.; Sahonta, S.-L.; Kappers, M. J.; Humphreys, C. J. [Department of Materials Science and Metallurgy, University of Cambridge, Charles Babbage Road, Cambridge CB3 0FS (United Kingdom); Horton, M. K. [Department of Materials, Imperial College London, Exhibition Road, London SW7 2AZ (United Kingdom); Pennycook, T. J. [SuperSTEM, STFC Daresbury Laboratories, Warrington WA4 4AD (United Kingdom); Department of Materials, University of Oxford, Parks Road, Oxford OX1 3PH (United Kingdom); Dusane, R. O. [Department of Metallurgical Engineering and Materials Science, Indian Institute of Technology Bombay, Mumbai 400076 (India); Moram, M. A. [Department of Materials Science and Metallurgy, University of Cambridge, Charles Babbage Road, Cambridge CB3 0FS (United Kingdom); Department of Materials, Imperial College London, Exhibition Road, London SW7 2AZ (United Kingdom)

    2015-12-14

    Aberration-corrected scanning transmission electron microscopy was used to investigate the core structures of threading dislocations in plan-view geometry of GaN films with a range of Si-doping levels and dislocation densities ranging between (5 ± 1) × 10{sup 8} and (10 ± 1) × 10{sup 9} cm{sup −2}. All a-type (edge) dislocation core structures in all samples formed 5/7-atom ring core structures, whereas all (a + c)-type (mixed) dislocations formed either double 5/6-atom, dissociated 7/4/8/4/9-atom, or dissociated 7/4/8/4/8/4/9-atom core structures. This shows that Si-doping does not affect threading dislocation core structures in GaN. However, electron beam damage at 300 keV produces 4-atom ring structures for (a + c)-type cores in Si-doped GaN.

  14. Abnormality diagnostic technology for nuclear power plants

    International Nuclear Information System (INIS)

    Ishikawa, Satoshi

    1986-01-01

    In nuclear power plants, it is feared that the failure of the installations containing radioactive substances may inflict serious damage on public and workers. Therefore in nuclear power plants, the ensuring of safety is planned by supposing hypothetical accidents which are not likely to occur from engineering viewpoint, and multiple protection measures are taken in the plant constitution. In addition to the safety measures from such hardware aspect, recently in order to prevent the occurrence of accidents by using various safety-confirming means, and to detect early when any accident occurred, the development and putting in practical use of many monitoring equipments have been promoted. In such background, the development of nuclear power generation supporting system was carried out for five years since fiscal year 1980, subsidized by the Ministry of International Trade and Industry, and in this report, the technology of equipment abnormality diagnosis developed as a part of that project and the diagnostic techniques for actual plants are described. The technology of diagnosing nuclear reactor abnormality includes the diagnosis of loose metal pieces and the abnormal vibration of in-core structures. The detection and diagnosis of valve leak and the diagnosis of the deterioration of detectors are also explained. (Kako, I.)

  15. Innovative diagnostics for ITER physics addressed in JET

    Energy Technology Data Exchange (ETDEWEB)

    Murari, A; Alfier, A; Pasqualotto, R [Associazione EURATOM-ENEA per la Fusione, Consorzio RFX, 4-35127 Padova (Italy); Edlington, T; Andrew, Y; Arnoux, G; Beurskens, M; Coad, P; Kempenaars, M; Kiptily, V; Meigs, A [Euratom/UKAEA Fusion Association, Culham Science Centre, Abingdon, Oxon, OX14 3DB (United Kingdom); Alonso, A; Hidalgo, C [Asociacion EURATOM-CIEMAT para Fusion, CIEMAT, Madrid (Spain); Crombe, C [Department of Applied Physics, Ghent University, Rozier 44, 900 Gent (Belgium); Gauthier, E; Giroud, C; Hong, S; Loarer, T [Association EURATOM-CEA, CEA Cadarache, 13108 Saint-Paul-lez-Durance (France); Tala, T [Association EURATOM-Tekes, VTT, PO Box 1000, FIN-02044 VTT (Finland)

    2008-12-15

    In recent years, JET diagnostic capability has been significantly improved to widen the range of physical phenomena that can be studied and thus contribute to the understanding of some ITER relevant issues. The most significant results reported in this paper refer to the plasma wall interactions, the interplay between core and edge physics and fast particles. A synergy between new infrared cameras, visible cameras and spectroscopy diagnostics has allowed investigating a series of new aspects of the plasma wall interactions. The power loads on the plasma facing components of JET main chambers have been assessed at steady state and during transient events like ELMs and disruptions. Evidence of filaments in the edge region of the plasma has been collected with a new fast visible camera and high resolution Thomson scattering. The physics of detached plasmas and some new aspects of dust formation have also been devoted particular attention. The influence of the edge plasma on the core has been investigated with upgraded active spectroscopy, providing new information on momentum transport and the effects of impurity injection on ELMs and ITBs and their interdependence. Given the fact that JET is the only machine with a plasma volume big enough to confine the alphas, a coherent programme of diagnostic developments for the energetic particles has been undertaken. With upgraded {gamma}-ray spectroscopy and a new scintillator probe, it is now possible to study both the redistribution and the losses of the fast particles in various plasma conditions.

  16. Modelling of magnetostriction of transformer magnetic core for vibration analysis

    Science.gov (United States)

    Marks, Janis; Vitolina, Sandra

    2017-12-01

    Magnetostriction is a phenomenon occurring in transformer core in normal operation mode. Yet in time, it can cause the delamination of magnetic core resulting in higher level of vibrations that are measured on the surface of transformer tank during diagnostic tests. The aim of this paper is to create a model for evaluating elastic deformations in magnetic core that can be used for power transformers with intensive vibrations in order to eliminate magnetostriction as a their cause. Description of the developed model in Matlab and COMSOL software is provided including restrictions concerning geometry and properties of materials, and the results of performed research on magnetic core anisotropy are provided. As a case study modelling of magnetostriction for 5-legged 200 MVA power transformer with the rated voltage of 13.8/137kV is conducted, based on which comparative analysis of vibration levels and elastic deformations is performed.

  17. Modelling of magnetostriction of transformer magnetic core for vibration analysis

    Directory of Open Access Journals (Sweden)

    Marks Janis

    2017-12-01

    Full Text Available Magnetostriction is a phenomenon occurring in transformer core in normal operation mode. Yet in time, it can cause the delamination of magnetic core resulting in higher level of vibrations that are measured on the surface of transformer tank during diagnostic tests. The aim of this paper is to create a model for evaluating elastic deformations in magnetic core that can be used for power transformers with intensive vibrations in order to eliminate magnetostriction as a their cause. Description of the developed model in Matlab and COMSOL software is provided including restrictions concerning geometry and properties of materials, and the results of performed research on magnetic core anisotropy are provided. As a case study modelling of magnetostriction for 5-legged 200 MVA power transformer with the rated voltage of 13.8/137kV is conducted, based on which comparative analysis of vibration levels and elastic deformations is performed.

  18. The neutron imaging diagnostic at NIF (invited).

    Science.gov (United States)

    Merrill, F E; Bower, D; Buckles, R; Clark, D D; Danly, C R; Drury, O B; Dzenitis, J M; Fatherley, V E; Fittinghoff, D N; Gallegos, R; Grim, G P; Guler, N; Loomis, E N; Lutz, S; Malone, R M; Martinson, D D; Mares, D; Morley, D J; Morgan, G L; Oertel, J A; Tregillis, I L; Volegov, P L; Weiss, P B; Wilde, C H; Wilson, D C

    2012-10-01

    A neutron imaging diagnostic has recently been commissioned at the National Ignition Facility (NIF). This new system is an important diagnostic tool for inertial fusion studies at the NIF for measuring the size and shape of the burning DT plasma during the ignition stage of Inertial Confinement Fusion (ICF) implosions. The imaging technique utilizes a pinhole neutron aperture, placed between the neutron source and a neutron detector. The detection system measures the two dimensional distribution of neutrons passing through the pinhole. This diagnostic has been designed to collect two images at two times. The long flight path for this diagnostic, 28 m, results in a chromatic separation of the neutrons, allowing the independently timed images to measure the source distribution for two neutron energies. Typically the first image measures the distribution of the 14 MeV neutrons and the second image of the 6-12 MeV neutrons. The combination of these two images has provided data on the size and shape of the burning plasma within the compressed capsule, as well as a measure of the quantity and spatial distribution of the cold fuel surrounding this core.

  19. The neutron imaging diagnostic at NIF (invited)

    Energy Technology Data Exchange (ETDEWEB)

    Merrill, F. E.; Clark, D. D.; Danly, C. R.; Drury, O. B.; Fatherley, V. E.; Gallegos, R.; Grim, G. P.; Guler, N.; Loomis, E. N.; Martinson, D. D.; Mares, D.; Morley, D. J.; Morgan, G. L.; Oertel, J. A.; Tregillis, I. L.; Volegov, P. L.; Wilde, C. H.; Wilson, D. C. [Los Alamos National Laboratory, Los Alamos, New Mexico 87544 (United States); Bower, D.; Dzenitis, J. M. [Livermore National Laboratory, Livermore, California 94550 (United States); and others

    2012-10-15

    A neutron imaging diagnostic has recently been commissioned at the National Ignition Facility (NIF). This new system is an important diagnostic tool for inertial fusion studies at the NIF for measuring the size and shape of the burning DT plasma during the ignition stage of Inertial Confinement Fusion (ICF) implosions. The imaging technique utilizes a pinhole neutron aperture, placed between the neutron source and a neutron detector. The detection system measures the two dimensional distribution of neutrons passing through the pinhole. This diagnostic has been designed to collect two images at two times. The long flight path for this diagnostic, 28 m, results in a chromatic separation of the neutrons, allowing the independently timed images to measure the source distribution for two neutron energies. Typically the first image measures the distribution of the 14 MeV neutrons and the second image of the 6-12 MeV neutrons. The combination of these two images has provided data on the size and shape of the burning plasma within the compressed capsule, as well as a measure of the quantity and spatial distribution of the cold fuel surrounding this core.

  20. Quality Assurance Programme for Computed Tomography: Diagnostic and Therapy Applications

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-08-15

    This publication presents a harmonized approach to quality assurance in the field of computed tomography applied to both diagnostics and therapy. It gives a careful analysis of the principles and specific instructions that can be used for a quality assurance programme for optimal performance and reduced patient dose in diagnostic radiology. In some cases, radiotherapy programmes are making a transition from 2-D to 3-D radiotherapy, a complex process which critically depends on accurate treatment planning. In this respect, the authors also provide detailed information about the elements needed for quality assurance testing, including those relating to accurate patient characterization as needed for radiotherapy treatment planning.

  1. Automated tru-cut imaging-guided core needle biopsy of canine ...

    African Journals Online (AJOL)

    The purpose of this study was to evaluate the diagnostic value of imaging-guided core needle biopsy for canine orbital mass diagnosis. A second excisional biopsy obtained during surgery or necropsy was used as the reference standard. A prospective feasibility study was conducted in 23 canine orbital masses at a single ...

  2. A condensed review of the core catcher in the LMR

    International Nuclear Information System (INIS)

    Lee, Yong Bum; Hahn, Do hee

    2001-03-01

    The overwhelming emphasis in reactor safety is on the prevention of core meltdown. Moreover, although there have been several accidents that have resulted in some fuel melting, to date there have been no accidents severe enough to cause the syndrome of core collapse, reactor vessel melt-through, containment penetration, and dispersal into the ground. Nevertheless, a number of proposals have been made for the design of core catcher systems to control or stop the motion of the molten core mass should such an accident take place. Core catchers may differ in both their location within the reactor system and in the mechanism that is used to cool and control the motion of the core debris. In this report the classification, configuration and main features of the core catcher are described. And also, the core catcher provisions in constructed and planned LMRs (Liquid Metal Reactors) are summarized

  3. Plasma Diagnostics of Coronal Dimming Events

    Science.gov (United States)

    Vanninathan, Kamalam; Veronig, Astrid M.; Dissauer, Karin; Temmer, Manuela

    2018-04-01

    Coronal mass ejections are often associated with coronal dimmings, i.e., transient dark regions that are most distinctly observed in Extreme Ultra-violet wavelengths. Using Atmospheric Imaging Assembly (AIA) data, we apply Differential Emission Measure diagnostics to study the plasma characteristics of six coronal dimming events. In the core dimming region, we find a steep and impulsive decrease of density with values up to 50%–70%. Five of the events also reveal an associated drop in temperature of 5%–25%. The secondary dimming regions also show a distinct decrease in density, but less strong, decreasing by 10%–45%. In both the core and the secondary dimming the density changes are much larger than the temperature changes, confirming that the dimming regions are mainly caused by plasma evacuation. In the core dimming, the plasma density reduces rapidly within the first 20–30 minutes after the flare start and does not recover for at least 10 hr later, whereas the secondary dimming tends to be more gradual and starts to replenish after 1–2 hr. The pre-event temperatures are higher in the core dimming (1.7–2.6 MK) than in the secondary dimming regions (1.6–2.0 MK). Both core and secondary dimmings are best observed in the AIA 211 and 193 Å filters. These findings suggest that the core dimming corresponds to the footpoints of the erupting flux rope rooted in the AR, while the secondary dimming represents plasma from overlying coronal structures that expand during the CME eruption.

  4. A comparison of diagnostic performance of vacuum-assisted biopsy and core needle biopsy for breast microcalcification: a systematic review and meta-analysis.

    Science.gov (United States)

    Huang, Xu Chen; Hu, Xu Hua; Wang, Xiao Ran; Zhou, Chao Xi; Wang, Fei Fei; Yang, Shan; Wang, Gui Ying

    2018-03-16

    Core needle biopsy (CNB) and vacuum-assisted biopsy (VAB) are both popularly used breast percutaneous biopsies. Both of them have become reliable alternatives to open surgical biopsy (OSB) for breast microcalcification (BM). It is controversial that which biopsy method is more accurate and safer for BM. Hence, we conducted this meta-analysis to compare the diagnostic performance between CNB and VAB for BM, aiming to find out the better method. Articles according with including and excluding criteria were collected from the databases, PubMed, Embase, and the Cochrane Library. Preset outcomes were abstracted and pooled to find out the potential advantages in CNB or VAB. Seven studies were identified and entered final meta-analysis from initially found 138 studies. The rate of ductal carcinoma in situ (DCIS) underestimation was significantly lower in VAB than CNB group [risk ratio (RR) = 1.83, 95% confidence interval (CI) 1.40 to 2.40, p < 0.001]. The microcalcification retrieval rate was significantly higher in VAB than CNB group (RR = 0.89, 95% CI 0.81 to 0.98, p = 0.02), while CNB owned a significantly lower complication rate than VAB (RR = 0.18, 95% CI 0.03 to 0.93, p = 0.04). The atypical ductal hyperplasia (ADH) underestimation rates were not compared for the limited number of studies reporting this outcome. Compared with CNB, VAB shows better diagnostic performance in DCIS underestimation rate and microcalcification retrieval rate. However, CNB shows a significantly lower complication rate. More studies are needed to verify these findings.

  5. TMI-2 core-examination program: INEL facilities-readiness study

    International Nuclear Information System (INIS)

    McLaughlin, T.B.

    1982-09-01

    This document is a review of the Idaho National Engineering Laboratory's (INEL) remote handling facilities. Their availability and readiness to conduct examination and analyses of TMI-2 core samples was determined. Examination of these samples require that the facilities be capable of receiving commercial casks, unloading canisters from the casks, opening the canisters, handling the fuel debris and assemblies, and performing various examinations. The documentation that was necessary for the INEL to have before the receipt of the core material was identified. The core information was also required for input to these documents. The costs, schedules, and a preliminary-project plan are presented for the tasks which are identified as prerequisites to the receipt of the first core sample

  6. Accuracy of Core Needle Biopsy Versus Fine Needle Aspiration Cytology for Diagnosing Salivary Gland Tumors

    Directory of Open Access Journals (Sweden)

    In Hye Song

    2015-03-01

    Full Text Available Background: Core needle biopsy is a relatively new technique used to diagnose salivary gland lesions, and its role in comparison with fine needle aspiration cytology needs to be refined. Methods: We compared the results of 228 ultrasound-guided core needle biopsy and 371 fine needle aspiration procedures performed on major salivary gland tumors with their postoperative histological diagnoses. Results: Core needle biopsy resulted in significantly higher sensitivity and more accurate tumor subtyping, especially for malignant tumors, than fine needle aspiration. No patient developed major complications after core needle biopsy. Conclusions: We recommend ultrasoundguided core needle biopsy as the primary diagnostic tool for the preoperative evaluation of patients with salivary gland lesions, especially when malignancy is suspected.

  7. Study on practical of eddy current testing of core and core support graphite components in HTTR

    International Nuclear Information System (INIS)

    Ishihara, Masahiro; Iyoku, Tatsuo; Ooka, Norikazu; Shindo, Yoshihisa; Kawae, Hidetoshi; Hayashi, Motomitsu; Kambe, Mamoru; Takahashi, Masaaki; Ide, Akira.

    1994-01-01

    Core and core support graphite components in the HTTR (High Temperature Engineering Test Reactor) are mainly made of nuclear-grade IG-110 and PGX graphites. Nondestructive inspection with Eddy Current Testing (ECT) is planned to be applied to these components. The method of ECT has been already established for metallic components, however, cannot be applied directly to the graphite ones, because the characteristics of graphite are quite different in micro-structure from those of metals. Therefore, ECT method and condition were studied for the application of the ECT to the graphite components. This paper describes the study on practical method and conditions of ECT for above mentioned graphite structures. (author)

  8. Cost allocation in distribution planning

    International Nuclear Information System (INIS)

    Engevall, S.

    1996-01-01

    This thesis concerns cost allocation problems in distribution planning. The cost allocation problems we study are illustrated using the distribution planning situation at the Logistics department of Norsk Hydro Olje AB. The planning situation is modeled as a Traveling Salesman Problem and a Vehicle Routing Problem with an inhomogeneous fleet. The cost allocation problems are the problems of how to divide the transportation costs among the customers served in each problem. The cost allocation problems are formulated as cooperative games, in characteristic function form, where the customers are defined to be the players. The games contain five and 21 players respectively. Game theoretical solution concepts such as the core, the nucleolus, the Shapley value and the τ-value are discussed. From the empirical results we can, among other things, conclude that the core of the Traveling Salesman Game is large, and that the core of the Vehicle Routing Game is empty. In the accounting of Norsk Hydro the cost per m 3 can be found for each tour. We conclude that for a certain definition of the characteristic function, a cost allocation according to this principle will not be included in the core of the Traveling Salesman Game. The models and methods presented in this thesis can be applied to transportation problems similar to that of Norsk Hydro, independent of the type of products that are delivered. 96 refs, 11 figs, 26 tabs

  9. Cost allocation in distribution planning

    Energy Technology Data Exchange (ETDEWEB)

    Engevall, S.

    1996-12-31

    This thesis concerns cost allocation problems in distribution planning. The cost allocation problems we study are illustrated using the distribution planning situation at the Logistics department of Norsk Hydro Olje AB. The planning situation is modeled as a Traveling Salesman Problem and a Vehicle Routing Problem with an inhomogeneous fleet. The cost allocation problems are the problems of how to divide the transportation costs among the customers served in each problem. The cost allocation problems are formulated as cooperative games, in characteristic function form, where the customers are defined to be the players. The games contain five and 21 players respectively. Game theoretical solution concepts such as the core, the nucleolus, the Shapley value and the {tau}-value are discussed. From the empirical results we can, among other things, conclude that the core of the Traveling Salesman Game is large, and that the core of the Vehicle Routing Game is empty. In the accounting of Norsk Hydro the cost per m{sup 3} can be found for each tour. We conclude that for a certain definition of the characteristic function, a cost allocation according to this principle will not be included in the core of the Traveling Salesman Game. The models and methods presented in this thesis can be applied to transportation problems similar to that of Norsk Hydro, independent of the type of products that are delivered. 96 refs, 11 figs, 26 tabs

  10. Cost allocation in distribution planning

    Energy Technology Data Exchange (ETDEWEB)

    Engevall, S

    1997-12-31

    This thesis concerns cost allocation problems in distribution planning. The cost allocation problems we study are illustrated using the distribution planning situation at the Logistics department of Norsk Hydro Olje AB. The planning situation is modeled as a Traveling Salesman Problem and a Vehicle Routing Problem with an inhomogeneous fleet. The cost allocation problems are the problems of how to divide the transportation costs among the customers served in each problem. The cost allocation problems are formulated as cooperative games, in characteristic function form, where the customers are defined to be the players. The games contain five and 21 players respectively. Game theoretical solution concepts such as the core, the nucleolus, the Shapley value and the {tau}-value are discussed. From the empirical results we can, among other things, conclude that the core of the Traveling Salesman Game is large, and that the core of the Vehicle Routing Game is empty. In the accounting of Norsk Hydro the cost per m{sup 3} can be found for each tour. We conclude that for a certain definition of the characteristic function, a cost allocation according to this principle will not be included in the core of the Traveling Salesman Game. The models and methods presented in this thesis can be applied to transportation problems similar to that of Norsk Hydro, independent of the type of products that are delivered. 96 refs, 11 figs, 26 tabs

  11. Degraded core studies at INEL

    International Nuclear Information System (INIS)

    Buescher, B.J.; Howe, T.M.; Miller, R.W.

    1982-01-01

    During 1980, planning of prototypical severe fuel damage tests to be conducted in the Power Burst Facility (PBF) to investigate fuel behavior in severe accidents up to temperatures of 2400 0 K was initiated. This first series of tests is designated Phase I. Also, a code development effort was initiated to provide a reliable predictive tool for core behavior during severe accidents. During 1981, an assessment of capabilities and preliminary planning were begun for an in-pile experimental program to investigate the behavior of larger arrays of previously irradiated fuel rods at temperatures through UO 2 melting. This latter series of tests is designated Phase II

  12. Research and development of in-core transducers at the CIAE

    International Nuclear Information System (INIS)

    Huang Yucai; Liu Yupu; Jia Guozhen; Liu Lianping

    1996-01-01

    In this paper, R and D of in-core transducers at the CIAE are briefly summarized. With the construction and commissioning of PWR nuclear power plant in China, fuel rod behaviour need to be studied carefully. As conventional transducers cannot meet the requirements of in-core applications, R and D of in-core transducers are developed. Since 1980's, several kinds of in-core transducers have been successfully fabricated and tested under the conditions simulating PWR. At present, in-pile tests of the transducers combining with the studies of individual behaviour of PWR fuel rod are being planned at the CIAE. (author). 11 refs, 12 figs, 4 tabs

  13. Core skills assessment to improve mathematical competency

    Science.gov (United States)

    Carr, Michael; Bowe, Brian; Fhloinn, Eabhnat Ní

    2013-12-01

    Many engineering undergraduates begin third-level education with significant deficiencies in their core mathematical skills. Every year, in the Dublin Institute of Technology, a diagnostic test is given to incoming first-year students, consistently revealing problems in basic mathematics. It is difficult to motivate students to address these problems; instead, they struggle through their degree, carrying a serious handicap of poor core mathematical skills, as confirmed by exploratory testing of final year students. In order to improve these skills, a pilot project was set up in which a 'module' in core mathematics was developed. The course material was basic, but 90% or higher was required to pass. Students were allowed to repeat this module throughout the year by completing an automated examination on WebCT populated by a question bank. Subsequent to the success of this pilot with third-year mechanical engineering students, the project was extended to five different engineering programmes, across three different year-groups. Full results and analysis of this project are presented, including responses to interviews carried out with a selection of the students involved.

  14. DOE Radiological Control Manual Core Training Program

    International Nuclear Information System (INIS)

    Scott, H.L.; Maisler, J.

    1993-01-01

    Over the past year, the Department of Energy (DOE) Office of Health (EH-40) has taken a leading role in the development of new standardized radiological control training programs for use throughout the DOE complex. The Department promulgated its Radiological Control (RadCon) Manual in June 1992. To ensure consistent application of the criteria presented in the RadCon Manual, standardized radiological control core training courses and training materials have been developed for implementation at all DOE facilities. In producing local training programs, standardized core courses are to be supplemented with site-specific lesson plans, viewgraphs, student handbooks, qualification standards, question banks, and wallet-sized training certificates. Training programs for General Employee Radiological Training, Radiological Worker I and II Training, and Radiological Control Technician Training have been disseminated. Also, training committees under the direction of the Office of Health (EH-40) have been established for the development of additional core training courses, development of examination banks, and the update of the existing core training courses. This paper discusses the current activities and future direction of the DOE radiological control core training program

  15. Integration of Biosafety into Core Facility Management

    Science.gov (United States)

    Fontes, Benjamin

    2013-01-01

    This presentation will discuss the implementation of biosafety policies for small, medium and large core laboratories with primary shared objectives of ensuring the control of biohazards to protect core facility operators and assure conformity with applicable state and federal policies, standards and guidelines. Of paramount importance is the educational process to inform core laboratories of biosafety principles and policies and to illustrate the technology and process pathways of the core laboratory for biosafety professionals. Elevating awareness of biohazards and the biosafety regulatory landscape among core facility operators is essential for the establishment of a framework for both project and material risk assessment. The goal of the biohazard risk assessment process is to identify the biohazard risk management parameters to conduct the procedure safely and in compliance with applicable regulations. An evaluation of the containment, protective equipment and work practices for the procedure for the level of risk identified is facilitated by the establishment of a core facility registration form for work with biohazards and other biological materials with potential risk. The final step in the biocontainment process is the assumption of Principal Investigator role with full responsibility for the structure of the site-specific biosafety program plan by core facility leadership. The presentation will provide example biohazard protocol reviews and accompanying containment measures for core laboratories at Yale University.

  16. Korrelasjon mellom core styrke, core stabilitet og utholdende styrke i core

    OpenAIRE

    Berg-Olsen, Andrea Marie; Fugelsøy, Eivor; Maurstad, Ann-Louise

    2010-01-01

    Formålet med studien var å se hvilke korrelasjon det er mellom core styrke, core stabilitet og utholdende styrke i core. Testingen bestod av tre hoveddeler hvor vi testet core styrke, core stabilitet og utholdende styrke i core. Innenfor core styrke og utholdende styrke i core ble tre ulike tester utført. Ved måling av core stabilitet ble det gjennomført kun en test. I core styrke ble isometrisk abdominal fleksjon, isometrisk rygg ekstensjon og isometrisk lateral fleksjon testet. Sit-ups p...

  17. Institutional plan FY 1998--FY 2003

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-10-01

    The Institutional Plan has been rearranged this year as a reflection of new Department of Energy (DOE) guidelines and to better illustrate the Laboratory`s mission-oriented focus. In Section 1 of this plan, the authors set forth their vision, mission, core competencies, strategic view, and related material. This section illustrates integration with the vision, mission, priorities, and core businesses of DOE. They define strategies, tactics, and guidelines and describe how they measure progress. In Section 2, they have elaborated on how they plan to address the Laboratory`s mission, describing programs and activities in the context of their role in this mission. Section 3 contains information on their approach to managing their business and operations. First they address the most critical issue safety. In this section, they confirm that Los Alamos is addressing the DOE critical success factors and describe the initiatives and plans that make their mission successful and leads them toward their vision. Section 4 contains details of their resources. 44 figs., 56 tabs.

  18. Analysis of RA-8 critical facility core in some configurations

    International Nuclear Information System (INIS)

    Abbate, Maximo J.; Sbaffoni, Maria M.

    2000-01-01

    The RA-8 critical facility was designated and built to be used in the experimental plan of the 'CAREM' Project but is, in itself, very versatile and adequate to perform many types of other experiments. The present paper includes calculated estimates of some critical configurations and comparisons with experimental results obtained during its start up. Results for Core 1 with homogeneous arrangement of rods containing 1.8 % enriched uranium, showed very good agreement. In fact, an experimentally critical configuration was reached with 1.300 rods and calculated values were: 1.310 using the WIMS code and 1.148 from the CONDOR code. Moreover, it was verified that the estimated number of 3.4% enriched uranium rods to be fabricated is enough to build a heterogeneous core or even a homogeneous core with this enrichment. The replacement of 3.4 % enriched uranium by 3.6 % will not present problems related with the original plan. (author)

  19. Diagnostics for FIRE: A Status Report

    International Nuclear Information System (INIS)

    Kenneth M. Young

    2002-01-01

    The mission for the proposed FIRE (Fusion Ignition Research Experiment) device is to ''attain, explore, understand and optimize fusion-dominated plasmas.'' Operation at Q * 5, for 20 sec with a fusion power output of *150 MW is the major goal. Attaining this mission sets demands for plasma measurement that are at least as comprehensive as on present tokamaks, with the additional capabilities needed for control of the plasma and for understanding the effects of the alpha-particles. Because of the planned operation in advanced tokamak scenarios, with steep transport barriers, the diagnostic instrumentation must be able to provide fine spatial and temporal resolution. It must also be able to withstand the impact of the intense neutron and gamma irradiation. There are practical engineering issues of minimizing radiation streaming while providing essential diagnostic access to the plasma. Many components will operate close to the first wall, e.g. ceramics and mineral insulated cable for magnetic diagnostics and mirrors for optical diagnostics; these components must be selected and mounted so that they will operate and survive in fluxes which require special material selection. The measurement requirements have been assessed so that the diagnostics for the FIRE device can be defined. Clearly a better set of diagnostics of alpha-particles than that available for TFTR is essential, since the alpha-particles provide the dominant sources of heating and of instability-drive in the plasma

  20. Web-based Core Design System Development

    International Nuclear Information System (INIS)

    Moon, So Young; Kim, Hyung Jin; Yang, Sung Tae; Hong, Sun Kwan

    2011-01-01

    The selection of a loading pattern is one of core design processes in the operation of a nuclear power plant. A potential new loading pattern is identified by selecting fuels that to not exceed the major limiting factors of the design and that satisfy the core design conditions for employing fuel data from the existing loading pattern of the current operating cycle. The selection of a loading pattern is also related to the cycle plan of an operating nuclear power plant and must meet safety and economic requirements. In selecting an appropriate loading pattern, all aspects, such as input creation, code runs and result processes are processed as text forms manually by a designer, all of which may be subject to human error, such as syntax or running errors. Time-consuming results analysis and decision-making processes are the most significant inefficiencies to avoid. A web-based nuclear plant core design system was developed here to remedy the shortcomings of an existing core design system. The proposed system adopts the general methodology of OPR1000 (Korea Standard Nuclear Power Plants) and Westinghouse-type plants. Additionally, it offers a GUI (Graphic User Interface)-based core design environment with a user-friendly interface for operators. It reduces human errors related to design model creation, computation, final reload core model selection, final output confirmation, and result data validation and verification. Most significantly, it reduces the core design time by more than 75% compared to its predecessor

  1. [Non-palpable breast cancer malignant on needle core biopsy and no malignancy in surgical excision: how to manage?].

    Science.gov (United States)

    Cheurfa, N; Giard, S

    2015-01-01

    Despite the standard management of non-palpable breast cancer (needle core biopsy diagnostic, accurate preoperative localization), there are differences in some cases between the malignant histo-pathological finding in diagnostic biopsy results and negative histo-pathological finding after surgical excision. The aim of this study is to evaluate this incidence and classifying them under three category: failure of surgical excision after preoperative identification; removal of the tumor was already completed by percutaneous biopsy; percutaneous biopsy true false positive. We conducted a study based on prospective database, all patients included in this study had partial mastectomy for ductal carcinoma in-situ or invasive cancer which was diagnosed by needle core biopsy and normal/benign after surgery. Regarding the partial mastectomy, 1863 was performed in the last three years in our center. Thirty-seven patients (2%) correspond our study criteria. After discussion of cases in our multidisciplinary reunion, 6 patients (16%) were considered as failure of surgical excision, 26 patients (70%) as true removal of the whole lesion in the core, and 5 patients (13%) as true false-positive cores. This is the first study witch investigate all factors that influence the results of negative final histo-pathological finding of surgical excision of the tumor after malignant diagnostic needle core biopsy. This rare situation need a multidisciplinary meeting to analyse all the steps of management and to determine causes of those false results and try to find adequate management to solve this problem. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  2. Operation planning device

    International Nuclear Information System (INIS)

    Watanabe, Takashi; Odakawa, Naoto; Erikuchi, Makoto; Okada, Masayuki; Koizumi, Atsuhiko.

    1996-01-01

    The device of the present invention provides a device suitable for monitoring a reactor core state and operation replanning in terms of reactor operation. Namely, (1) an operation result difference judging means judges that replanning is necessary when the operation results deviates from the operation planning, (2) an operation replanning rule data base storing means stores a deviation key which shows various kinds of states where the results deviate from the planning and a rule for replanning for returning to the operation planning on every deviating key, (3) an operation replanning means forms a new operation planning in accordance with the rule which is retrieved based on the deviation key, (4) an operation planning optimizing rule data base storing means evaluates the reformed planning and stores it on every evaluation item, (5) an operation planning optimization means correct the operation planning data so as to be optimized when the evaluation of the means (4) is less than a reference value, and (6) an operation planning display means edits adaptable operation planning data and the result of the evaluation and displays them. (I.S.)

  3. THREE-DIMENSIONAL CORE-COLLAPSE SUPERNOVA SIMULATED USING A 15 M{sub ⊙} PROGENITOR

    Energy Technology Data Exchange (ETDEWEB)

    Lentz, Eric J.; Mezzacappa, Anthony; Harris, J. Austin; Yakunin, Konstantin N. [Department of Physics and Astronomy, University of Tennessee, Knoxville, TN 37996-1200 (United States); Bruenn, Stephen W. [Department of Physics, Florida Atlantic University, 777 Glades Road, Boca Raton, FL 33431-0991 (United States); Hix, W. Raphael [Physics Division, Oak Ridge National Laboratory, P.O. Box 2008, Oak Ridge, TN 37831-6354 (United States); Messer, O. E. Bronson [National Center for Computational Sciences, Oak Ridge National Laboratory, P.O. Box 2008, Oak Ridge, TN 37831-6164 (United States); Endeve, Eirik [Computer Science and Mathematics Division, Oak Ridge National Laboratory, P.O. Box 2008, Oak Ridge, TN 37831-6164 (United States); Blondin, John M. [Department of Physics, North Carolina State University, Raleigh, NC 27695-8202 (United States); Marronetti, Pedro, E-mail: elentz@utk.edu [Physics Division, National Science Foundation, Arlington, VA 22207 (United States)

    2015-07-10

    We have performed ab initio neutrino radiation hydrodynamics simulations in three and two spatial dimensions (3D and 2D) of core-collapse supernovae from the same 15 M{sub ☉} progenitor through 440 ms after core bounce. Both 3D and 2D models achieve explosions; however, the onset of explosion (shock revival) is delayed by ∼100 ms in 3D relative to the 2D counterpart and the growth of the diagnostic explosion energy is slower. This is consistent with previously reported 3D simulations utilizing iron-core progenitors with dense mantles. In the ∼100 ms before the onset of explosion, diagnostics of neutrino heating and turbulent kinetic energy favor earlier explosion in 2D. During the delay, the angular scale of convective plumes reaching the shock surface grows and explosion in 3D is ultimately lead by a single, large-angle plume, giving the expanding shock a directional orientation not dissimilar from those imposed by axial symmetry in 2D simulations. We posit that shock revival and explosion in the 3D simulation may be delayed until sufficiently large plumes form, whereas such plumes form more rapidly in 2D, permitting earlier explosions.

  4. MFTF plasma diagnostics data acquisition system

    International Nuclear Information System (INIS)

    Davis, G.E.; Coffield, F.E.

    1979-01-01

    The initial goal of the Data Acquisition System (DAS) is to control 11 instruments chosen as the startup diagnostic set and to collect, process, and display the data that these instruments produce. These instruments are described in a paper by Stan Thomas, et. al. entitled ''MFTF Plasma Diagnostics System.'' The DAS must be modular and flexible enough to allow upgrades in the quantity of data taken by an instrument, and also to allow new instruments to be added to the system. This is particularly necessary to support a research project where needs and requirements may change rapidly as a result of experimental findings. Typically, the startup configuration of the diagnostic instruments will contain only a fraction of the planned detectors, and produce approximately one half the data that the expanded version is designed to generate. Expansion of the system will occur in fiscal year 1982

  5. Progress in Neutron Diagnostics at JET

    Czech Academy of Sciences Publication Activity Database

    Mlynář, Jan; Bonheure, G.; Murari, A.; Bertalot, L.; Angelone, M.; Pillon, M.; Conroy, S.; Ericsson, G.; Kaellne, J.; Popovichev, S.

    2006-01-01

    Roč. 56, suppl.B (2006), B118-B124 ISSN 0011-4626. [Symposium on Plasma Physics and Technology /22nd./. Praha, 26.6.2006-29.6.2006] Institutional research plan: CEZ:AV0Z20430508 Keywords : tokamak * JET * fusion * neutrons diagnostics Subject RIV: BL - Plasma and Gas Discharge Physics Impact factor: 0.568, year: 2006

  6. Spectroscopic diagnostics of high temperature plasmas

    International Nuclear Information System (INIS)

    Moos, W.

    1990-01-01

    A three-year research program for the development of novel XUV spectroscopic diagnostics for magnetically confined fusion plasmas is proposed. The new diagnostic system will use layered synthetic microstructures (LSM) coated, flat and curved surfaces as dispersive elements in spectrometers and narrow band XUV filter arrays. In the framework of the proposed program we will develop impurity monitors for poloidal and toroidal resolved measurements on PBX-M and Alcator C-Mod, imaging XUV spectrometers for electron density and temperature fluctuation measurements in the hot plasma core in TEXT or other similar tokamaks and plasma imaging devices in soft x-ray light for impurity behavior studies during RF heating on Phaedrus T and carbon pellet ablation in Alcator C-Mod. Recent results related to use of multilayer in XUV plasma spectroscopy are presented. We also discuss the latest results reviewed to q o and local poloidal field measurements using Zeeman polarimetry

  7. ICF in the U.S.: Facilities and diagnostics

    International Nuclear Information System (INIS)

    Coleman, L.W.

    1988-08-01

    In the last few years there has been significant progress in ICF research in laboratories in the United States and elsewhere. These advances have occurred in areas that range from demonstrating an innovative laser beam smoothing techniques important for both directly and indirectly driven ICF, to achieving a more complete understanding of capsule implosions and related physics. This progress has been possible because of the capabilities provided by the ICF laser-target facilities currently in operation and the new developments in diagnostics, particularly for measurements of the implosion process and the conditions in the compressed capsule core. Both of these topics, facilities and selected new diagnostics capabilities in the US ICF Program, are summarized in this paper. 32 refs., 19 figs., 6 tabs

  8. Using Multi-Core Systems for Rover Autonomy

    Science.gov (United States)

    Clement, Brad; Estlin, Tara; Bornstein, Benjamin; Springer, Paul; Anderson, Robert C.

    2010-01-01

    Task Objectives are: (1) Develop and demonstrate key capabilities for rover long-range science operations using multi-core computing, (a) Adapt three rover technologies to execute on SOA multi-core processor (b) Illustrate performance improvements achieved (c) Demonstrate adapted capabilities with rover hardware, (2) Targeting three high-level autonomy technologies (a) Two for onboard data analysis (b) One for onboard command sequencing/planning, (3) Technologies identified as enabling for future missions, (4)Benefits will be measured along several metrics: (a) Execution time / Power requirements (b) Number of data products processed per unit time (c) Solution quality

  9. Greater Biopsy Core Number Is Associated With Improved Biochemical Control in Patients Treated With Permanent Prostate Brachytherapy

    International Nuclear Information System (INIS)

    Bittner, Nathan; Merrick, Gregory S.; Galbreath, Robert W.; Butler, Wayne M.; Adamovich, Edward; Wallner, Kent E.

    2010-01-01

    Purpose: Standard prostate biopsy schemes underestimate Gleason score in a significant percentage of cases. Extended biopsy improves diagnostic accuracy and provides more reliable prognostic information. In this study, we tested the hypothesis that greater biopsy core number should result in improved treatment outcome through better tailoring of therapy. Methods and Materials: From April 1995 to May 2006, 1,613 prostate cancer patients were treated with permanent brachytherapy. Patients were divided into five groups stratified by the number of prostate biopsy cores (≤6, 7-9, 10-12, 13-20, and >20 cores). Biochemical progression-free survival (bPFS), cause-specific survival (CSS), and overall survival (OS) were evaluated as a function of core number. Results: The median patient age was 66 years, and the median preimplant prostate-specific antigen was 6.5 ng/mL. The overall 10-year bPFS, CSS, and OS were 95.6%, 98.3%, and 78.6%, respectively. When bPFS was analyzed as a function of core number, the 10-year bPFS for patients with >20, 13-20, 10-12, 7-9 and ≤6 cores was 100%, 100%, 98.3%, 95.8%, and 93.0% (p < 0.001), respectively. When evaluated by treatment era (1995-2000 vs. 2001-2006), the number of biopsy cores remained a statistically significant predictor of bPFS. On multivariate analysis, the number of biopsy cores was predictive of bPFS but did not predict for CSS or OS. Conclusion: Greater biopsy core number was associated with a statistically significant improvement in bPFS. Comprehensive regional sampling of the prostate may enhance diagnostic accuracy compared to a standard biopsy scheme, resulting in better tailoring of therapy.

  10. Software for project-based learning of robot motion planning

    Science.gov (United States)

    Moll, Mark; Bordeaux, Janice; Kavraki, Lydia E.

    2013-12-01

    Motion planning is a core problem in robotics concerned with finding feasible paths for a given robot. Motion planning algorithms perform a search in the high-dimensional continuous space of robot configurations and exemplify many of the core algorithmic concepts of search algorithms and associated data structures. Motion planning algorithms can be explained in a simplified two-dimensional setting, but this masks many of the subtleties and complexities of the underlying problem. We have developed software for project-based learning of motion planning that enables deep learning. The projects that we have developed allow advanced undergraduate students and graduate students to reflect on the performance of existing textbook algorithms and their own variations on such algorithms. Formative assessment has been conducted at three institutions. The core of the software used for this teaching module is also used within the Robot Operating System, a widely adopted platform by the robotics research community. This allows for transfer of knowledge and skills to robotics research projects involving a large variety robot hardware platforms.

  11. The strategic plan for combating antimicrobial resistance in Gulf Cooperation Council States.

    Science.gov (United States)

    Balkhy, Hanan H; Assiri, Abdullah M; Mousa, Haifa Al; Al-Abri, Seif S; Al-Katheeri, Huda; Alansari, Huda; Abdulrazzaq, Najiba M; Aidara-Kane, Awa; Pittet, Didier

    2016-01-01

    The Gulf Cooperation Council Center for Infection Control (GCC-IC) has placed the emergence of antimicrobial resistance (AMR) on the top of its agenda for the past four years. The board members have developed the initial draft for the GCC strategic plan for combating AMR in 2014. The strategic plan stems from the WHO mandate to combat AMR at all levels. The need for engaging a large number of stakeholders has prompted the GCC-IC to engage a wider core of professionals in finalizing the plan. A multi-disciplinary group of more than 40 experts were then identified. And a workshop was conducted in Riyadh January 2015 and included, for the first time, representation of relevant ministries and agencies as well as international experts in the field. Participants worked over a period of two and a half days in different groups. International experts shared the global experiences and challenges in addressing human, food, animal, and environmental aspects of controlling AMR. Participants were then divided into 4 groups each to address the human, animal, microbiological and diagnostic, or the environmental aspect of AMR. At the end of the workshop, the strategic plan was revised and endorsed by all participants. The GCC-IC board members then approved it as the strategic plan for AMR. The document produced here is the first GCC strategic plan addressing AMR, which shall be adopted by GCC countries to develop country-based plans and related key performance indicators (KPIs). It is now the role of each country to identify the body that will be accountable for implementing the plan at the country level. Copyright © 2016 King Saud Bin Abdulaziz University for Health Sciences. Published by Elsevier Ltd. All rights reserved.

  12. Spatially resolved soft x-ray diagnostics in fusion energy research

    International Nuclear Information System (INIS)

    Mlynar, J.; Weinzettl, V.; Imrisek, M.; Loeffelmann, V.

    2013-01-01

    With construction of ITER, the fusion community has progressed into a new stage of research with increased focus on reactor technologies. Corresponding development of diagnostic systems for fusion is required, including research of novel diagnostic methods, validation of radiation hard detectors, and tests of sensors for real-time operation and control, which comprise development of tools for fast data analyses. In parallel, diagnostic systems on running fusion experiments substantially contribute to better understanding of reactor-relevant plasma physics, in particular of energy confinement, plasma stability and transport of impurities. In this respect, spatially resolved Soft X-ray (SXR) diagnostic systems present an interesting case study of development towards reactor-relevant systems. In magnetic confinement fusion research, spatial distribution of SXR radiation with spectral range typically 1 keV - 15 keV is mostly measured by a photosensitive single-row semiconductor elements in a pinhole camera shielded by a beryllium foil. The SXR intensity strongly depends on plasma density, temperature and effective charge, which carry a valuable information on the plasma core physics. Data from SXR diagnostic can be also used for the operation control, among others due to their sensitivity to heavy impurity concentration or to the position of the peak temperature. In order to reconstruct the spatial distribution of SXR plasma emission from the measured line integrated signals, several tomographic methods have been developed and validated. However, the semiconductor elements cannot survive in harsh conditions of future fusion reactors due to radiation damage, which calls for development of radiation hard SXR cameras. In this contribution, role of the SXR diagnostics will be presented in experience and future plans of the Czech tokamak COMPASS (IPP Prague) and the French tokamak TORE SUPRA (CEA Cadarache). In IPP Prague, data from SXR cameras recently contributed to

  13. Density-based and transport-based core-periphery structures in networks.

    Science.gov (United States)

    Lee, Sang Hoon; Cucuringu, Mihai; Porter, Mason A

    2014-03-01

    Networks often possess mesoscale structures, and studying them can yield insights into both structure and function. It is most common to study community structure, but numerous other types of mesoscale structures also exist. In this paper, we examine core-periphery structures based on both density and transport. In such structures, core network components are well-connected both among themselves and to peripheral components, which are not well-connected to anything. We examine core-periphery structures in a wide range of examples of transportation, social, and financial networks-including road networks in large urban areas, a rabbit warren, a dolphin social network, a European interbank network, and a migration network between counties in the United States. We illustrate that a recently developed transport-based notion of node coreness is very useful for characterizing transportation networks. We also generalize this notion to examine core versus peripheral edges, and we show that the resulting diagnostic is also useful for transportation networks. To examine the properties of transportation networks further, we develop a family of generative models of roadlike networks. We illustrate the effect of the dimensionality of the embedding space on transportation networks, and we demonstrate that the correlations between different measures of coreness can be very different for different types of networks.

  14. Review of diagnostic tools to investigate the physical state of rapid granular filters

    DEFF Research Database (Denmark)

    Lopato, Laure Rose; Binning, Philip John; Arvin, Erik

    2012-01-01

    This paper reviews diagnostic tools that can be used at waterworks to investigate the physical and operational state of rapid granular filters. Diagnostic tools can be of interest for the Water Safety Plans of WHO to monitor filters in a proactive manner. The review considers conventional and state...

  15. The calculation of the MEU-HEU coupled core in the KUCA

    International Nuclear Information System (INIS)

    Hayashi, M.; Shiroya, S.; Kanda, K.; Shibata, T.

    1984-01-01

    The KUCA has a plan for critical experiments of the MEU-HEU coupled core in 1984. The neutronics calculation has been performed for the MEU-HEU coupled core in the KUCA. The GGC-4 and THERMOS were used to generate the four-group constants and the 2D-FEM-KUR, based on the finite-element method, was used for the diffusion calculation. The calculations with four-group constants agreed with experiments within 1.8% for the both single-cores with the MEU and the HEU. (author)

  16. Development of high performance core for large fast breeder reactors

    International Nuclear Information System (INIS)

    Inoue, Kotaro; Kawashima, Katsuyuki; Watari, Yoshio.

    1982-01-01

    Subsequently to the fast breeder prototype reactor ''Monju'', the construction of a demonstration reactor with 1000 MWe output is planned. This research aims at the establishment of the concept of a large core with excellent fuel breeding property and safety for a demonstration and commercial reactors. For the purpose, the optimum specification of fuel design as a large core was clarified, and the new construction of a core was examined, in which a disk-shaped blanket with thin peripheral edge is introduced at the center of a core. As the result, such prospect was obtained that the time for fuel doubling would be 1/2, and the energy generated in a core collapse accident would be about 1/5 as compared with a large core using the same fuel as ''Monju''. Generally, as a core is enlarged, the rate of breeding lowers. If a worst core collapse accident occurs, the scale of accident will be very large in the case of a ''Monju'' type large core. In an unhomogeneous core, an internal blanket is provided in the core for the purpose of improving the breeding property and safety. Hitachi Ltd. developed the concept of a large core unhomogeneous in axial direction and proposed it. The research on the fuel design for a large core, an unhomogeneous core and its core collapse accident is reported. (Kako, I.)

  17. Test plan: Potash Core Test. WIPP experimental program borehole plugging

    International Nuclear Information System (INIS)

    Christensen, C.L.

    1979-09-01

    The Potash Core Test will utilize a WIPP emplaced plug to obtain samples of an in-situ cured plug of known mix constituents for bench scale testing. An earlier effort involved recovery at the salt horizon of Plug 217, a 17 year old plug in a potash exploration hole for bond testing, but the lack of particulars in the emplacement precluded significant determination of plug performance

  18. Nonrigid Image Registration for Head and Neck Cancer Radiotherapy Treatment Planning With PET/CT

    International Nuclear Information System (INIS)

    Ireland, Rob H.; Dyker, Karen E.; Barber, David C.; Wood, Steven M.; Hanney, Michael B.; Tindale, Wendy B.; Woodhouse, Neil; Hoggard, Nigel; Conway, John; Robinson, Martin H.

    2007-01-01

    Purpose: Head and neck radiotherapy planning with positron emission tomography/computed tomography (PET/CT) requires the images to be reliably registered with treatment planning CT. Acquiring PET/CT in treatment position is problematic, and in practice for some patients it may be beneficial to use diagnostic PET/CT for radiotherapy planning. Therefore, the aim of this study was first to quantify the image registration accuracy of PET/CT to radiotherapy CT and, second, to assess whether PET/CT acquired in diagnostic position can be registered to planning CT. Methods and Materials: Positron emission tomography/CT acquired in diagnostic and treatment position for five patients with head and neck cancer was registered to radiotherapy planning CT using both rigid and nonrigid image registration. The root mean squared error for each method was calculated from a set of anatomic landmarks marked by four independent observers. Results: Nonrigid and rigid registration errors for treatment position PET/CT to planning CT were 2.77 ± 0.80 mm and 4.96 ± 2.38 mm, respectively, p = 0.001. Applying the nonrigid registration to diagnostic position PET/CT produced a more accurate match to the planning CT than rigid registration of treatment position PET/CT (3.20 ± 1.22 mm and 4.96 ± 2.38 mm, respectively, p = 0.012). Conclusions: Nonrigid registration provides a more accurate registration of head and neck PET/CT to treatment planning CT than rigid registration. In addition, nonrigid registration of PET/CT acquired with patients in a standardized, diagnostic position can provide images registered to planning CT with greater accuracy than a rigid registration of PET/CT images acquired in treatment position. This may allow greater flexibility in the timing of PET/CT for head and neck cancer patients due to undergo radiotherapy

  19. KNGR core proection calculator, software, verification and validation plan

    International Nuclear Information System (INIS)

    Kim, Jang Yeol; Park, Jong Kyun; Lee, Ki Young; Lee, Jang Soo; Cheon, Se Woo

    2001-05-01

    This document describes the Software Verification and Validation Plan(SVVP) Guidance to be used in reviewing the Software Program Manual(SPM) in Korean Next Generation Reactor(KNGR) projects. This document is intended for a verifier or reviewer who is involved with performing of software verification and validation task activity in KNGR projects. This document includeds the basic philosophy, performing V and V effort, software testing techniques, criteria of review and audit on the safety software V and V activity. Major review topics on safety software addresses three kinds of characteristics based on Standard Review Plan(SRP) Chapter 7, Branch Technical Position(BTP)-14 : management characteristics, implementation characteristics and resources characteristics when reviewing on SVVP. Based on major topics of this document, we have produced the evaluation items list such as checklist in Appendix A

  20. Process and overview of diagnostics integration in ITER ports

    International Nuclear Information System (INIS)

    Drevon, J.M.; Walsh, M.; Andrew, P.; Barnsley, R.; Bertalot, L.; Bock, M. de; Bora, D.; Bouhamou, R.; Direz, M.F.; Encheva, A.; Fang, T.; Feder, R.; Giacomin, T.; Hellermann, M. von; Jakhar, S.; Johnson, D.; Kaschuk, Y.; Kusama, Y.; Lee, H.G.; Levesy, B.

    2013-01-01

    Highlights: ► An overview of the Port Integration hardware for tenant system hosting inside ITER diagnostics ports is given. ► The main challenges for diagnostic port integration engineering are presented. ► The actions taken for a common modular approach and a coordinated design are detailed. -- Abstract: ITER will have a set of 45 diagnostics to ensure controlled operation. Many of them are integrated in the ITER ports. This paper addresses the integration process of the diagnostic systems and the approach taken to enable coordinated progress. An overview of the Port Integration hardware introduces the various structures needed for hosting tenant systems inside ITER diagnostics ports. The responsibilities of the different parties involved (ITER Organization and the Domestic Agencies) are outlined. The main challenges for diagnostic port integration engineering are summarized. The plan for a common approach to design and manufacture of the supporting structures, in particular the Port Plug is detailed. A coordinated design including common components and a common approach for neutronic analyses is proposed. One particular port, the equatorial port 11, is used to illustrate the approach

  1. Eight meeting of the ITER diagnostic expert group

    International Nuclear Information System (INIS)

    Costley, A.E.; Young, K.M.

    1998-01-01

    The 8. Meeting of the ITER Diagnostics Expert Group which was held in San Diego, February 1998 had two main technical goals: to discuss the status and plans for developing kinetic control, and to review the current status of the design of the magnetic system

  2. Design of a reactor core in the Oma Full MOX-ABWR

    International Nuclear Information System (INIS)

    Hama, Teruo

    1999-01-01

    The Electric Power Development Co., Ltd. has progressed a construction plan on an improved boiling-water reactor aiming at loading of MOX fuel in all reactor cores (full MOX-ABWR) at Oma-cho, Aomori prefecture, which is a last stage on application of approval on establishment at present. Here were described on outlines of reactor core in the full MOX-ABWR and its safety evaluation. For the full MOX-ABWR loading MOX fuel assembly into all reactor core, thermal and mechanical design analysis of fuel bars and core design analysis were conducted. As a result, it was confirmed that judgement standards in mixed core of MOX fuel and uranium fuel were also applicable as well as that in uranium fuel. (G.K.)

  3. Measurements of confined alphas and tritons in the MHD quiescent core of TFTR plasmas using the pellet charge exchange diagnostic

    International Nuclear Information System (INIS)

    Medley, S.S.; Budny, R.V.; Mansfield, D.K.

    1996-05-01

    The energy distributions and radial density profiles of the fast confined trapped alpha particles in DT experiments on TFTR are being measured in the energy range 0.5--3.5 MeV using a Pellet Charge eXchange (PCX) diagnostic. A brief description of the measurement technique which involves active neutral particle analysis using the ablation cloud surrounding an injected impurity pellet as the neutralizer is presented. This paper focuses on alpha and triton measurements in the core of MHD quiescent TFTR discharges where the expected classical slowing down and pitch angle scattering effects are not complicated by stochastic ripple diffusion and sawtooth activity. In particular, the first measurement of the alpha slowing down distribution up to the birth energy, obtained using boron pellet injection, is presented. The measurements are compared with predictions using either the TRANSP Monte-Carlo code and/or a Fokker-Planck Post-TRANSP processor code, which assumes that the alphas and tritons are well confined and slow down classically. Both the shape of the measured alpha and triton energy distributions and their density ratios are in good agreement with the code calculations. The authors conclude that the PCX measurements are consistent with classical thermalization of the fusion-generated alphas and tritons

  4. Looking for trouble? Diagnostics expanding disease and producing patients.

    Science.gov (United States)

    Hofmann, Bjørn

    2018-05-23

    Novel tests give great opportunities for earlier and more precise diagnostics. At the same time, new tests expand disease, produce patients, and cause unnecessary harm in overdiagnosis and overtreatment. How can we evaluate diagnostics to obtain the benefits and avoid harm? One way is to pay close attention to the diagnostic process and its core concepts. Doing so reveals 3 errors that expand disease and increase overdiagnosis. The first error is to decouple diagnostics from harm, eg, by diagnosing insignificant conditions. The second error is to bypass proper validation of the relationship between test indicator and disease, eg, by introducing biomarkers for Alzheimer's disease before the tests are properly validated. The third error is to couple the name of disease to insignificant or indecisive indicators, eg, by lending the cancer name to preconditions, such as ductal carcinoma in situ. We need to avoid these errors to promote beneficial testing, bar harmful diagnostics, and evade unwarranted expansion of disease. Accordingly, we must stop identifying and testing for conditions that are only remotely associated with harm. We need more stringent verification of tests, and we must avoid naming indicators and indicative conditions after diseases. If not, we will end like ancient tragic heroes, succumbing because of our very best abilities. © 2018 John Wiley & Sons, Ltd.

  5. “Burning Plasma” Diagnostics for the Physics of JET and ITER

    Czech Academy of Sciences Publication Activity Database

    Murari, A.; Bertalot, L.; Bonheure, G.; Conroy, S.; Ericsson, G.; Kiptily, V.G.; Lawson, K.; Popovichev, S.; Tardocchi, M.; Afanasyiev, V.; Angelone, M.; Fasoli, A.; Kallne, J.; Mironov, M.; Mlynář, Jan; Testa, D.; Zastrow, K.D.

    2005-01-01

    Roč. 47, 12B (2005), B249-B262 ISSN 0741-3335. [EPS Conference on Plasma Physics/32nd./. Tarragona, 27.6.2005-1.7.2005] Institutional research plan: CEZ:AV0Z20430508 Keywords : JET * ITER * neutrons diagnostics * alphas diagnostics * burning plasma * reactor * isotopic composition Subject RIV: BL - Plasma and Gas Discharge Physics Impact factor: 2.902, year: 2005 http://eps2005.ciemat.es

  6. DEMO diagnostics and burn control

    Energy Technology Data Exchange (ETDEWEB)

    Biel, Wolfgang, E-mail: w.biel@fz-juelich.de [Institute of Energy and Climate Research, Forschungszentrum Jülich GmbH, Jülich (Germany); Department of Applied Physics, Ghent University (Belgium); Baar, Marco de [FOM-Institute DIFFER, Nieuwegein (Netherlands); Eindhoven University of Technology (Netherlands); Dinklage, Andreas [Max-Planck-Institut für Plasmaphysik, Greifswald (Germany); Felici, Federico [Eindhoven University of Technology (Netherlands); König, Ralf [Max-Planck-Institut für Plasmaphysik, Greifswald (Germany); Meister, Hans; Treutterer, Wolfgang [Max-Planck-Institut für Plasmaphysik, Garching (Germany); Wenninger, Ronald [Max-Planck-Institut für Plasmaphysik, Garching (Germany); EFDA Power Plant Physics and Technology, Garching (Germany)

    2015-10-15

    Highlights: • An initial concept for the DEMO diagnostic and control system is presented. • A preliminary list of control functions and candidate diagnostics is developed. • Challenges regarding disruptions, power exhaust and radiation control are highlighted. • The need for introducing realistic control margins is emphasized. • On outline of the future R&D plan is presented. - Abstract: The development of the control system for a tokamak demonstration fusion reactor (DEMO) faces unprecedented challenges. First, the requirements for control reliability and accuracy are more stringent than on existing fusion devices: any loss of plasma control on DEMO may result in a disruption which could damage the inner wall of the machine, while operating the device with larger margins against the operational limits would lead to a reduction of the electrical output power. Second, the performance of DEMO control is limited by space restrictions for the implementation of components (optimization of the tritium breeding rate), by lifetime issues for the front-end parts (neutron and gamma radiation, erosion and deposition acting on all components) and by slow, weak and indirect action of the available actuators (plasma shaping, heating and fuelling). The European DEMO conceptual design studies include the development of a reliable control system, since the details of the achievable plasma scenario and the machine design may depend on the actual performance of the control system. In the first phase of development, an initial understanding of the prime choices of diagnostic methods applicable to DEMO, implementation and performance issues, the interrelation with the plasma scenario definition, and the planning of necessary future R&D have been obtained.

  7. Study on the reactivity behavior partially loaded reactor cores using SIMULATE-3

    International Nuclear Information System (INIS)

    Holzer, Robert; Zeitz, Andreas; Grimminger, Werner; Lubczyk, Tobias

    2009-01-01

    The reactor core design for the NPP Gundremmingen unit B and C is performed since several years using the validated 3D reactor core calculation program SIMULATE-3. The authors describe a special application of the program to study the reactivity for different partial core loadings. Based on the comparison with results of the program CASMO-4 the program SIMULATE-3 was validated for the calculation of partially loaded reactor cores. For the planned reactor operation in NPP Gundremmingen using new MOX fuel elements the reactivity behavior was studied with respect to the KTA-Code requirements.

  8. Appendix BB: long coring facility (LCF)

    International Nuclear Information System (INIS)

    Driscoll, A.H.; Silva, A.J.

    1981-01-01

    During the 1979 performance period the Engineering Design of the Long Coring Facility has addressed a variety of tasks relating to the establishment of a series of operating parameters for a conceptual 50 meter long coring system. The results of these efforts have indicated that an operational system capable of the recovery of 50 meter long cores, from oceanic depths in sediments of 400 gm cm 2 is wholly possible given existing technology. Specific tasks included in the 1979 Engineering Design are as follows: (1) Hydrodynamic Stability; (2) Corer Structural Stability; (3) Corer Penetration Mechanics; (4) Anticipated Corer Pullout forces; (5) LCF Cable Dynamics; and (6) Core Head Instrumentation. Within the realm of Subseabed Disposal Programs Master Plan the LCF, as a part of the Instrumentation Development activity, is currently on schedule. Delays in receiving funding during 1979 have reduced, some what, the latitude enjoyed by the LCF project and have limited our progress to a point where any future delay can result in the LCF's falling behind the program schedule. However, at this time the LCF is considered to be on schedule, but lacking in flexibility to respond to any major contingency that may arise in the future

  9. Radiographer-performed stereotactic needle core biopsy: Making a difference

    Energy Technology Data Exchange (ETDEWEB)

    Dixon, Anne-Marie [School of Health Studies, University of Bradford, Unity Building, 25 Trinity Road, Bradford BD5 0BB (United Kingdom)], E-mail: a.m.dixon@leeds.ac.uk; Dearnley, Christine [School of Health Studies, University of Bradford, Unity Building, 25 Trinity Road, Bradford BD5 0BB (United Kingdom)

    2008-12-15

    This case study describes a qualitative investigation of the experiences of 14 experienced mammography radiographers who successfully undertook a formal programme of education and training in stereotactic needle core biopsy (SNCB) of the breast. They now routinely perform SNCB within symptomatic and screening breast services in a variety of NHS hospitals across the country. All 14 radiographers completed a semi-structured postal questionnaire approximately six months after the end of the course. A tentative theory derived from the data suggests that the professional challenge associated with radiographer-performed SNCB builds personal confidence and effects positive change. Three main categories emerging from the data - challenge, confidence and change are underpinned by two main themes - educational, professional and service drivers that promote the realisation of goals and vision; and personal, peer and external motivation sustained by respect, recognition and reward. SNCB role extension as explored in this study is having a positive and transformational impact on patient users of breast diagnostic clinical services and on the professional health carers providing them. The key drivers for this as identified in the study are a formal educational experience, professional role extension opportunities and the NHS modernisation process. The participants experienced positive change as individuals and as professional breast cancer multidisciplinary team members. Academic and financial rewards, respect and recognition from colleagues across professional disciplines and from patients, were key motivators that sustained the process. This study indicates that radiographer-performed SNCB can help deliver the NHS Plan and the NHS Cancer Plan and in doing so has the potential to improve the working lives of health care professionals and ultimately to improve the quality of care for patients.

  10. Radiographer-performed stereotactic needle core biopsy: Making a difference

    International Nuclear Information System (INIS)

    Dixon, Anne-Marie; Dearnley, Christine

    2008-01-01

    This case study describes a qualitative investigation of the experiences of 14 experienced mammography radiographers who successfully undertook a formal programme of education and training in stereotactic needle core biopsy (SNCB) of the breast. They now routinely perform SNCB within symptomatic and screening breast services in a variety of NHS hospitals across the country. All 14 radiographers completed a semi-structured postal questionnaire approximately six months after the end of the course. A tentative theory derived from the data suggests that the professional challenge associated with radiographer-performed SNCB builds personal confidence and effects positive change. Three main categories emerging from the data - challenge, confidence and change are underpinned by two main themes - educational, professional and service drivers that promote the realisation of goals and vision; and personal, peer and external motivation sustained by respect, recognition and reward. SNCB role extension as explored in this study is having a positive and transformational impact on patient users of breast diagnostic clinical services and on the professional health carers providing them. The key drivers for this as identified in the study are a formal educational experience, professional role extension opportunities and the NHS modernisation process. The participants experienced positive change as individuals and as professional breast cancer multidisciplinary team members. Academic and financial rewards, respect and recognition from colleagues across professional disciplines and from patients, were key motivators that sustained the process. This study indicates that radiographer-performed SNCB can help deliver the NHS Plan and the NHS Cancer Plan and in doing so has the potential to improve the working lives of health care professionals and ultimately to improve the quality of care for patients

  11. Draft of diagnostic techniques for primary coolant circuit facilities using control computer

    International Nuclear Information System (INIS)

    Suchy, R.; Procka, V.; Murin, V.; Rybarova, D.

    A method is proposed of in-service on-line diagnostics of primary circuit selected parts by means of a control computer. Computer processing will involve the measurements of neutron flux, pressure difference in pumps and in the core, and the vibrations of primary circuit mechanical parts. (H.S.)

  12. Core biopsy as a simple and effective diagnostic tool in head and neck focal myositis.

    Science.gov (United States)

    Tan, Chun Yee; Chong, Sheldon; Shaw, Chi-Kee Leslie

    2015-12-01

    Most unilateral head and neck masses are benign, although malignancy is a possibility in some cases. However, there are other rare causes of unilateral neck masses, such as focal myositis, which is a rare, benign condition belonging to the family of inflammatory pseudotumors of the skeletal muscles, with rare presentations in the head and neck region. Focal myositis presents as a rapidly enlarging neck mass that can be misdiagnosed by fine-needle aspiration biopsy and/or radiologic imaging as either an infective or a neoplastic process. To date, there are only 5 reported cases of adult focal myositis of the sternocleidomastoid muscle in the medical literature. In this article, the authors present 2 cases involving patients with focal myositis of the sternocleidomastoid muscle that were successfully diagnosed with core-needle biopsy and managed conservatively. The pros and cons of fine-needle aspiration biopsy and core-needle biopsy are discussed. Based on the authors' results, fine-needle aspiration biopsy universally fails to provide the diagnosis of focal myositis. In contrast, core-needle biopsy successfully diagnosed focal myositis in both of our patients. Both of them had complete resolution with conservative management.

  13. Report on the diagnostics for control of the fusion DEMO reactors

    International Nuclear Information System (INIS)

    2014-05-01

    The range of diagnostics that can be used in DEMO will be severely restricted compared to that used in the current experiments or to be used in ITER. Therefore, a study is planned on the technical feasibility of sensors and diagnostics on the basis of specific tokamak and helical DEMO designs, with the involvement of a wide range of specialists covering reactor design, diagnostics, neutronics, reactor structure, remote maintenance, plasma physics, plasma and machine control, and computer simulation. Topics included typical characteristic times of target plasma behavior, diagnostics tools with their resolution and lifetime, response time of actuators, and plasmas. Through these studies, possible candidates for DEMO diagnostics were identified. The outcome of two years of activities is summarized in this report with a recommendation to the government of Japan. (J.P.N.)

  14. Characterization of the core poloidal flow at ASDEX Upgrade

    Science.gov (United States)

    Lebschy, Alexander

    2017-10-01

    An essential result from neoclassical (NC) theory is that the fluid poloidal rotation (upol) of the main ions is strongly damped by magnetic pumping and, therefore, expected to be small (theory has been found at both DIII-D and TCV. This is qualitatively consistent with the edge results from both Alcator C-Mod and ASDEX Upgrade (AUG). At AUG thanks to an upgrade of the core charge exchange recombination spectroscopy (CXRS) diagnostics, the core upol can be evaluated through the inboard-outboard asymmetry of the toroidal rotation with an accuracy of 0.5 - 1 km / s . This measurement also provides the missing ingredient to evaluate the core (E-> × B->) velocity (uE-> × B->) via the radial force balance equation. At AUG the core upol (0.35 × B-> determined from CXRS and the perpendicular velocity measured from turbulence propagation. The difference between these two quantities is the turbulent phase velocity. The gathered dataset indicates that the transition in the turbulence regime occurs after the saturation of the energy confinement time. The author thankfully acknowledges the financial support from the Helmholtz Association of German Research Centers through the Helmholtz Young Investigators Group program.

  15. Diagnostics of mobile dust in scrape-off layer plasmas

    International Nuclear Information System (INIS)

    Ratynskaia, S; Castaldo, C; Bergsaaker, H; Rudakov, D

    2011-01-01

    Dust production and accumulation pose serious safety and operational implications for the next generation fusion devices. Mobile dust particles can result in core plasma contamination with impurities, and those with high velocities can significantly contribute to the wall erosion. Diagnostics for monitoring dust in tokamaks during plasma discharges are hence important as they can provide information on dust velocity and size, and-in some cases-on dust composition. Such measurements are also valuable as an input for theoretical models of dust dynamics in scrape-off layer plasmas. Existing in situ dust diagnostics, focusing on the range of dust parameters they can detect, are reviewed. Particular attention is paid to the diagnostics which allow us to detect tails of the dust velocity and size distributions, e.g. small and very fast particles. Some of the techniques discussed have been adopted from space-related research and have been shown to be feasible and useful for tokamak applications as well.

  16. Circulating nucleic acids as a new diagnostic tool

    Czech Academy of Sciences Publication Activity Database

    Urbanová, Markéta; Plzák, J.; Strnad, Hynek; Betka, J.

    2010-01-01

    Roč. 15, č. 2 (2010), s. 242-259 ISSN 1425-8153 R&D Projects: GA MŠk 2B06106 Institutional research plan: CEZ:AV0Z50520514 Keywords : circulating nucleic acids * diagnostics * cancer Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 1.455, year: 2010

  17. Diagnostic Technology Development for Core Internal Structure in CANDU reactor

    International Nuclear Information System (INIS)

    Jung, Hyun Kyu; Cheong, Y. M.; Lee, Y. S. and others

    2005-04-01

    Degradation of critical components of nuclear power plants has become important as the operating years of plants increase. The necessity of degradation study including measurement and monitoring technology has increased continuously. Because the fuel channels and the neighboring sensing tubes and control rods are particularly one of the critical components in CANDU nuclear plant, they are treated as a major research target in order to counteract the possible problems and establish the counterplan for the CANDU reactor safety improvement. To ensure the core structure integrity in CANDU nuclear plant, the following 2 research tasks were performed: Development of NDE technologies for the gap measurement between the fuel channels and LIN tubes. Development of vibration monitoring technology of the fuel channels and sensing tubes. The technologies developed in this study could contribute to the nuclear safety and estimation of the remaining life of operating CANDU nuclear power plants

  18. Revolutionizing radiographic diagnostic accuracy in periodontics

    Directory of Open Access Journals (Sweden)

    Brijesh Sharma

    2016-01-01

    Full Text Available Effective diagnostic accuracy has in some way been the missing link between periodontal diagnosis and treatment. Most of the clinicians rely on the conventional two-dimensional (2D radiographs. But being a 2D image, it has its own limitations. 2D images at times can give an incomplete picture about the severity or type of disease and can further affect the treatment plan. Cone beam computed tomography (CBCT has a better potential for detecting periodontal bone defects with accuracy. The purpose here is to describe how CBCT imaging is beneficial in accurate diagnosis and will lead to a precise treatment plan.

  19. Temporal reflectance from a light pulse irradiated medium embedded with highly scattering cores

    International Nuclear Information System (INIS)

    Hsu Peifeng; Lu Xiaodong

    2007-01-01

    This paper presents a new approach to utilize ultrashort pulsed laser for optical diagnostics with numerical simulations. The method is based on the use of ultrafast pulses with a pulsewidth selected according to the probed medium's radiative property and/or size. Our previous work in nonhomogeneous media has shown that the resulting time-resolved reflectance signal will have a unique characteristic: it will show a direct correlation of ballistic photon travel time and interface location, which is in between different layers or nonhomogeneous regions. The premise is based on utilizing the medium's structural information carried by the ballistic and snake photons without being masked by the diffuse photons. In this study, the space-time correlation is further explored in the case of minimally scattered photons from a large scattering coefficient core region embedded within a less-scattering medium. Time-resolved reflectance signals of the single scattering core and multiple scattering cores within a three-dimensional medium demonstrate the concept and illustrate the additional effect due to the scattered photons from the core region. A unique temporal signal profile's correlation at various detector positions with respect to the scattering core is explained in detail. The result has important implications. This approach will lead to a much simpler and more precise determination of the probed medium's composition or structure. Due to the large computational requirement to obtain the physical details of the light pulse propagation inside highly scattering multi-dimensional media, the reverse Monte-Carlo method is used. The potential applications of the method include non-destructive diagnostics, optical imaging, and remote sensing of underwater objects

  20. Dome style heavy wall steel casting manufactured by metallic core mould system

    International Nuclear Information System (INIS)

    Yamamoto, Shiro; Saeki, Keiji; Hirose, Yutaka; Takebayashi, Kazunari; Kawasaki, Masatoshi

    1986-01-01

    Semi-spherical thick walled steel castings are one of the main products of Nippon Chutanko K.K., but there have been the problems of internal defects peculiar to large thick walled steel castings, and the various improvements have been carried out so far for the manufacturing method, but still some of those remains. Based on the anxiety about the reliability of large steel castings, the conversion to forging has been studied. For the purpose of thoroughly improving the internal quality of thick walled steel castings to compete with forgings, on the basis of the operating experience of chills, the development of the casting techniques changing cores completely to metallic cores has been advanced. After the preliminary experiment using models, a semi-spherical thick walled steel casting mentioned before was manufactured by this metallic core casting method for trial, and the detailed investigation was carried out. As the result, the excellent internal quality was confirmed, accordingly at present, the production is made by this method. The form, dimensions and specification of the semi-spherical thick walled steel castings, the conventional casting plan, the metallic core casting plan, the design of metallic cores, molding and casting, and the examination of the castings made for trial are reported. (Kako, I.)

  1. Core concept for long operating cycle simplified BWR (LSBWR)

    International Nuclear Information System (INIS)

    Kouji, Hiraiwa; Noriyuki, Yoshida; Mikihide, Nakamaru; Hideaki, Heki; Masanori, Aritomi

    2002-01-01

    An innovative core concept for a long operating cycle simplified BWR (LSBWR) is currently being developed under a Toshiba Corporation and Tokyo Institute of Technology joint study. In this core concept, the combination of enriched uranium oxide fuels and loose-pitched lattice is adopted for an easy application of natural circulation. A combination of enriched gadolinium and 0.7-times sized small bundle with peripheral-positioned gadolinium rod is also adopted as a key design concept for 15-year cycle operation. Based on three-dimensional nuclear and thermal hydraulic calculation, a nuclear design for fuel bundle has been determined. Core performance has been evaluated based on this bundle design and shows that thermal performance and reactivity characteristics meet core design criteria. Additionally, a control rod operation plan for an extension of control rod life has been successfully determined. (author)

  2. LBNL Institutional Plan, FY 1996--2001. Draft

    International Nuclear Information System (INIS)

    1995-06-01

    The FY 1996-2001 Institutional Plan provides an overview of the Lawrence Berkeley National Laboratory mission, strategic plan, core business areas, critical success factors, and the resource requirements to fulfill its mission in support of national needs in fundamental science and technology, energy resources, and environmental quality. The Strategic Plan section identifies long-range conditions that will influence the Laboratory, as well as potential research trends and management implications. The Core Business Areas section identifies those initiatives that are potential new research programs representing major long-term opportunities for the Laboratory, and the resources required for their implementation. It also summarizes current programs and potential changes in research program activity, science and technology partnerships, and university and science education. The Critical Success Factors section reviews human resources; work force diversity; environment, safety, and health programs; management practices; site and facility needs; and communications and trust. The Resource Projections are estimates of required budgetary authority for the Laboratory's ongoing research programs. The Institutional Plan is a management report for integration with the Department of Energy's strategic planning activities, developed through an annual planning process. The plan identifies technical and administrative directions in the context of the national energy policy and research needs and the Department of Energy's program planning initiatives. Preparation of the plan is coordinated by the Office for Planning and Communications from information contributed by the Laboratory's scientific and support divisions

  3. LBNL Institutional Plan, FY 1996--2001. Draft

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-06-01

    The FY 1996-2001 Institutional Plan provides an overview of the Lawrence Berkeley National Laboratory mission, strategic plan, core business areas, critical success factors, and the resource requirements to fulfill its mission in support of national needs in fundamental science and technology, energy resources, and environmental quality. The Strategic Plan section identifies long-range conditions that will influence the Laboratory, as well as potential research trends and management implications. The Core Business Areas section identifies those initiatives that are potential new research programs representing major long-term opportunities for the Laboratory, and the resources required for their implementation. It also summarizes current programs and potential changes in research program activity, science and technology partnerships, and university and science education. The Critical Success Factors section reviews human resources; work force diversity; environment, safety, and health programs; management practices; site and facility needs; and communications and trust. The Resource Projections are estimates of required budgetary authority for the Laboratory`s ongoing research programs. The Institutional Plan is a management report for integration with the Department of Energy`s strategic planning activities, developed through an annual planning process. The plan identifies technical and administrative directions in the context of the national energy policy and research needs and the Department of Energy`s program planning initiatives. Preparation of the plan is coordinated by the Office for Planning and Communications from information contributed by the Laboratory`s scientific and support divisions.

  4. Monitoring of core barrel vibrations in WWER type reactor using out-of-reactor ionization chambers

    International Nuclear Information System (INIS)

    Dach, K.

    1982-01-01

    Vibration of the core barrel is least desirable for safe operation of the PWR reactor. These mechanical vibrations are in correlation with the fluctuations of neutron flux density whose time and frequency analysis serves failure diagnosis. The mathematical model is described of the transfer of mechanical vibrations of the core barrel to neutron noise. Other steps are indicated indispensable for the application of the method of neutron noise analysis for in-service diagnostics of nuclear power plants. (Z.M.)

  5. SU-F-T-617: Remotely Pre-Planned Stereotactic Ablative Radiation Therapy: Validation of Treatment Plan Quality

    International Nuclear Information System (INIS)

    Juang, T; Bush, K; Loo, B; Gensheimer, M

    2016-01-01

    Purpose: We propose a workflow to improve access to stereotactic ablative radiation therapy (SABR) for rural patients. When implemented, a separate trip to the central facility for simulation can be eliminated. Two elements are required: (1) Fabrication of custom immobilization devices to match positioning on prior diagnostic CT (dxCT). (2) Remote radiation pre-planning on dxCT, with transfer of contours/plan to simulation CT (simCT) and initiation of treatment same-day or next day. In this retrospective study, we validated part 2 of the workflow using patients already treated with SABR for upper lobe lung tumors. Methods: Target/normal structures were contoured on dxCT; a plan was created and approved by the physician. Structures were transferred to simCT using deformable image registration and the plan was re-optimized on simCT. Plan quality was evaluated through comparison to gold-standard structures contoured on simCT and a gold-standard plan based on these structures. Workflow-generated plan quality in this study represents a worst-case scenario as these patients were not treated using custom immobilization to match dxCT position as would be done when the workflow is implemented clinically. Results: 5/6 plans created through the pre-planning workflow were clinically acceptable. For all six plans, the gold-standard GTV received full prescription dose, along with median PTV V95%=95.2% and median PTV D95%=95.4%. Median GTV DSC=0.80, indicating high degree of similarity between the deformed and gold-standard GTV contours despite small GTV sizes (mean=3.0cc). One outlier (DSC=0.49) resulted in inadequate PTV coverage (V95%=62.9%) in the workflow plan; in clinical practice, this mismatch between deformed/gold-standard GTV would be revised by the physician after deformable registration. For all patients, normal tissue doses were comparable to the gold-standard plan and well within constraints. Conclusion: Pre-planning SABR cases on diagnostic imaging generated

  6. Ductal carcinoma in a multiple fibroadenoma: Diagnostic inaccuracies

    Directory of Open Access Journals (Sweden)

    Rao Shalinee

    2010-01-01

    Full Text Available We present the diagnostic inaccuracies encountered in a case of multiple fibroadenoma with malignant transformation. A 30-year-old lady presented with lump in the right breast of one month duration which on clinical examination, X-ray mammogram, sonomammogram were suggestive of multiple fibroadenomas. Fine needle aspiration cytology of the largest lump revealed features of malignancy and a core biopsy showed pleomorphic cells that could not be categorized. Due to the clinical, radiological and pathological diagnostic ambiguity, lumpectomy was performed and frozen section showed features of only conventional fibroadenoma. Representative bits on routine processing showed only features of fibroadenoma. Hence, complete submission of all lumps was done, which revealed fibroadenoma with invasive ductal carcinoma in one. Patient underwent modified radical mastectomy which showed multiple fibroadenomas, focal fibrocystic disease with a focus of residual invasive tumor and metastatic deposit in one axillary lymph node. This case report highlights the diagnostic challenges in detecting malignancy in fibroadenoma and a need for extensive tissue sampling in multiple fibroadenomas to detect the rare occurrence of carcinoma.

  7. Ductal carcinoma in a multiple fibroadenoma: diagnostic inaccuracies.

    Science.gov (United States)

    Rao, Shalinee; Latha, P Suvarna; Ravi, A; Thanka, J

    2010-01-01

    We present the diagnostic inaccuracies encountered in a case of multiple fibroadenoma with malignant transformation. A 30-year-old lady presented with lump in the right breast of one month duration which on clinical examination, X-ray mammogram, sonomammogram were suggestive of multiple fibroadenomas. Fine needle aspiration cytology of the largest lump revealed features of malignancy and a core biopsy showed pleomorphic cells that could not be categorized. Due to the clinical, radiological and pathological diagnostic ambiguity, lumpectomy was performed and frozen section showed features of only conventional fibroadenoma. Representative bits on routine processing showed only features of fibroadenoma. Hence, complete submission of all lumps was done, which revealed fibroadenoma with invasive ductal carcinoma in one. Patient underwent modified radical mastectomy which showed multiple fibroadenomas, focal fibrocystic disease with a focus of residual invasive tumor and metastatic deposit in one axillary lymph node. This case report highlights the diagnostic challenges in detecting malignancy in fibroadenoma and a need for extensive tissue sampling in multiple fibroadenomas to detect the rare occurrence of carcinoma.

  8. Epistemic and Doxastic Planning

    DEFF Research Database (Denmark)

    Jensen, Martin Holm

    This thesis is concerned with planning and logic, which are both core areas of Artificial Intelligence (AI). A wide range of research disciplines deal with AI, including philosophy, economy, psychology, neuroscience, mathematics and computer science. The approach of this thesis is based...

  9. Refinery production planning and scheduling: the refining core business

    Directory of Open Access Journals (Sweden)

    M. Joly

    2012-06-01

    Full Text Available Intelligent production planning and scheduling are of paramount importance to ensure refinery profitability, logistic reliability and safety at the local and corporate levels. In Brazil, such activities play a particularly critical role, since the Brazilian downstream model is moving towards a demand-driven model rather than a supply-driven one. Moreover, new and specialized non-linear constraints are continuously being incorporated into these large-scale problems: increases in oil prices implying the need for processing poor quality crudes, increasing demand and new demand patterns for petroleum products, new stringent environmental regulations related to clean fuels and start-up of new production technologies embedded into more complex refining schemes. This paper aims at clarifying the central role of refinery planning and scheduling activities in the Petrobras refining business. Major past and present results are outlined and corporate long-term strategies to deal with present and future challenges are presented.

  10. Preliminary considerations on the startup phase for the ASTRID core

    International Nuclear Information System (INIS)

    Mignot, G.

    2015-01-01

    This paper presents preliminary considerations on the startup phase for the ASTRID core, as well as an overview of the different steps before reaching the optimised equilibrium core. The start-up phase is assumed to cover the period between loading the dummy core into the reactor (for commissioning tests) and achieving the optimised equilibrium core. Four main stages are considered: a first stage of start-up tests before fuel core loading, a second stage related to zero power and power ramp-up tests, a third stage corresponding to the transition from the first core to the equilibrium contractual core, and the last stage to reach the optimised performance for the equilibrium core. In the two last stages, a sub-assembly surveillance plan based on post-irradiation examinations is taken into account. As this work is in its preliminary stages, the first scenarios shown for the start-up phase must not be considered as the ASTRID reference scenarios. The scenarios strongly depend on the assumptions considered in the analysis, whereas those discussed in this paper aim at outlining the content and the duration of the starting phases for the ASTRID core, which will be useful in subsequently assessing the core sub-assembly fabrication needs. Assumptions for the start-up phase will be updated in accordance with progress on the ASTRID core design development and core qualification programme. (author)

  11. Ra reactor operation plan for 1976 - Annex 6; Prilog 6 - Plan rada reaktora RA za 1976. godinu

    Energy Technology Data Exchange (ETDEWEB)

    Martinc, R [Institute of Nuclear Sciences Boris Kidric, Vinca, Beograd (Serbia and Montenegro)

    1976-01-15

    Contrary to previous years the RA reactor operation plan for 1976 is conditioned by more uncertainties than ever for the following reasons. It is planned for February to repair the components in order to eliminate the consequences of leaking from the vertical experimental channel VK-4 which happened in december 1975. Apart from this, measurements related to transfer of the core to highly enriched fuel under minimum power are foreseen to be performed in February. In April, it would be indispensable to locate the point of He gas leaking and its prevention. Core transfer to highly enriched fuel is planned for April for testing of the fuel elements under operating conditions and step by step increase of the power density up to the nominal power. Complete plan for core transfer would be available by the end of February 1976. It is planned to make-up for the mentioned delays from May-December 1976. [Serbo-Croat] Za razliku od prethodnih godina izrada plana rada reaktora RA za 1976. godinu vezana je za mnogo vise neizvesnosti nego ikada ranije iz sledecih razloga. U februaru se vrsi remont opreme i uklanjanja posledica procurivanja vertikalnog eksperimentalog kanala VK-4, koje se dogodilo decembra 1975. Sem toga u februaru se vrse merenja na minimalnim snagama u sklopu priprema za prelazak na novo gorivo. U aprilu ce biti neophodno lociranje mesta gde istice He gas kao i otklanjanje uzroka ovog curenja. Planirano je da se u aprilu ubaci novo gorivo u jezgro u cilju testiranja pod radnim uslovima uz postepeno povecanje snage do nominalne. Planirano je da se smanjeni obim rada usled navedenih uslova nadoknadi u potpunosti u periodu maj-decembar 1976.

  12. Radiation therapy treatment planning: CT, MR imaging and three-dimensional planning

    International Nuclear Information System (INIS)

    Lichter, A.S.

    1987-01-01

    The accuracy and sophistication of radiation therapy treatment planning have increased rapidly in the last decade. Currently, CT-based treatment planning is standard throughout the country. Care must be taken when CT is used for treatment planning because of clear differences between diagnostic scans and scans intended for therapeutic management. The use of CT in radiation therapy planning is discussed and illustrated. MR imaging adds another dimension to treatment planning. The ability to use MR imaging directly in treatment planning involves an additional complex set of capabilities from a treatment planning system. The ability to unwarp the geometrically distorted MR image is a first step. Three-dimensional dose calculations are important to display the dose on sagittal and acoronal sections. The ability to integrate the MR and CT images into a unified radiographic image is critical. CT and MR images are two-dimensional representations of a three-dimensional problem. Through sophisticated computer graphics techniques, radiation therapists are now able to integrate a three-dimensional image of the patient into the treatment planning process. This allows the use of noncoplanar treatment plans and a detailed analysis of tumor and normal tissue anatomy; it is the first step toward a fully conformational treatment planning system. These concepts are illustrated and future research goals outlined

  13. Design of Diagnostics: Case Studies for Wendelstein 7-X

    International Nuclear Information System (INIS)

    Dreier, H.; Dinklage, A.; Fischer, R.; Hirsch, M.; Kornejew, P.; Pasch, E.

    2005-01-01

    The set of start-up diagnostics for Wendelstein 7-X is oriented to resolve physical issues of stellarator optimization [1]. The diagnostics philosophy of W7-X aims at extendable set-ups which are to be supplemented along the operation of the device. Planning diagnostics directly lead to the requirement to optimize their respective outcome. In many cases, the optimization is much restricted by technical constraints. But even in those cases, figures of robustness of the chosen design settings are beneficial for the diagnostic strategy. In this paper a framework for diagnostic design is presented employing the Bayesian probability theory. Part of the approach can be regarded as a virtual diagnostic, which describes the future experimental unit including its error statistics and is able to produce artificial data. The virtual diagnostic is fed with mock-up quantities of interest and hence it enables the designer to compare the outcome of the virtual diagnostic with its input. For the design of diagnostics in fusion experiments several figures of merit are possible, depend- ing on the optimization goal. Here physical questions like estimation of the density distribution or the density gradient are possible optimization targets as well as technical issues as the robustness of density measurements, e.g, for controlling purposes. Also the estimation of derived quantities - like gradients needed for modeling of the bootstrap current or of the radial electric field - might be considered to be the goal of a diagnostic design. (Author)

  14. Introducing FACETS, the Framework Application for Core-Edge Transport Simulations

    International Nuclear Information System (INIS)

    Cary, John R.; Candy, Jeff; Cohen, Ronald H.; Krasheninnikov, Sergei I.; McCune, Douglas C.; Estep, Donald J.; Larson, Jay W.; Malony, Allen; Worley, Patrick H.; Carlsson, Johann Anders; Hakim, A.H.; Hamill, P.; Kruger, Scott E.; Muzsala, S.; Pletzer, Alexander; Shasharina, Svetlana; Wade-Stein, D.; Wang, N.; McInnes, Lois C.; Wildey, T.; Casper, T.A.; Diachin, Lori A.; Epperly, Thomas; Rognlien, T.D.; Fahey, Mark R.; Kuehn, Jeffery A.; Morris, A.; Shende, Sameer; Feibush, E.; Hammett, Gregory W.; Indireshkumar, K.; Ludescher, C.; Randerson, L.; Stotler, D.; Pigarov, A.; Bonoli, P.; Chang, C.S.; D'Ippolito, D.A.; Colella, Philip; Keyes, David E.; Bramley, R.

    2007-01-01

    The FACETS (Framework Application for Core-Edge Transport Simulations) project began in January 2007 with the goal of providing core to wall transport modeling of a tokamak fusion reactor. This involves coupling previously separate computations for the core, edge, and wall regions. Such a coupling is primarily through connection regions of lower dimensionality. The project has started developing a component-based coupling framework to bring together models for each of these regions. In the first year, the core model will be a 1 dimensional model (1D transport across flux surfaces coupled to a 2D equilibrium) with fixed equilibrium. The initial edge model will be the fluid model, UEDGE, but inclusion of kinetic models is planned for the out years. The project also has an embedded Scientific Application Partnership that is examining embedding a full-scale turbulence model for obtaining the crosssurface fluxes into a core transport code.

  15. Cruise report on geotechnical core processing; Cruise: ATLAS-84, ISHTE Component Test, R/V Melville Sept.-Oct., 1984

    International Nuclear Information System (INIS)

    Silva, A.J.; Lipkin, J.; Brandes, H.

    1986-01-01

    The primary objectives of the geotechnical core processing program on the component test cruise were to: a) obtain additional base line physical property data of the ISHTE site sediments in MPG-I; b) compare strengths determined in the cored sediments to those obtained in situ with the In Situ Vane (ISV) system; and c) obtain samples for detailed laboratory analysis. Original plans called for processing of at least four cores obtained with the 10.2 cm APL hydrostatic corer (HLC) and at least one core obtained with the 20.3 cm WHOI corer (GC). If possible it was also planned to process one of the HLC cores at dockside in an attempt to assess the effects of ship motions on shear strength measurements. Shipboard laboratory facilities were set up for geotechnical processing with the URI sampling gear. Sandia Laboratory supplied a laboratory miniature vane device and apparatus for conducting thermal conductivity tests. Shipboard measurements included shear strength (miniature vane and Torvane) and thermal conductivity. Sampling included disturbed samples for water content, bulk density and classification tests and undisturbed samples for consolidation, permeability, strength, creep and fabric analyses. Unfortunately no GC cores were obtained. Three HLC cores, obtained on two lowerings of the large platform, were processed in considerable detail. In addition it was decided to process three of the box cores recovered by the SIO biology group. Therefore, a total of six cores were processed for geotechnical purposes. The dockside processing plan was deleted because of uncertainties caused by recovery procedures and the fact that only three HLC cores were available. Results are summarized

  16. Image-guided automated needle biopsy of 106 thoracic lesions: a retrospective review of diagnostic accuracy and complication rates

    International Nuclear Information System (INIS)

    Connor, S.; Dyer, J.; Guest, P.

    2000-01-01

    We reviewed the diagnostic accuracy and complication rates of transthoracic needle biopsy (TNB) with an automated 18-gauge core biopsy needle and gun, using either fluoroscopic or CT guidance. One hundred six lesions were biopsied in 103 patients between 1992 and 1998. Hard-copy images, imaging reports, pathology reports and clinical notes were reviewed. In 3 patients it was not possible to establish the lesion as either malignant or benign from the available follow-up, so these were removed from the analysis of diagnostic accuracy. Adequate samples for histological diagnosis were obtained in 104 of 106 (98 %) biopsies. There were 75 of 85 (88 %) true-positive core biopsies for malignant lesions and a specific cell type was identified in 70 of 85 (82 %) cases. A specific histological diagnosis was obtained in 12 of 18 (66 %) biopsies. There was a 19 % rate of pneumothorax with only 2.4 % requiring drainage. Minor haemoptysis occurred in 3.8 % of procedures. The TNB technique with an automated core biopsy needle provides a high level of diagnostic accuracy, effectively distinguishes cell type in malignancy and provides a definite diagnosis in benign disease more frequently than fine needle aspiration (FNA). There is no increased complication rate compared with FNA. (orig.)

  17. Test Plan for Rotary Mode Core Sample Truck Grapple Hoist Level Wind System

    International Nuclear Information System (INIS)

    BOGER, R.M.

    1999-01-01

    A Grapple Hoist Assembly is currently used on the Rotary Mode Core Sampling Trucks (RMCSTs) to actuate the sampler and retrieve the pintle rod during sampling operations. The hoist assembly includes a driven drum approximately two inches wide and six inches in diameter that rotates to pay out or reel in the 5/32-in. cable The current Grapple Hoist Assembly, detailed on drawing H-2-690057, is prone to ''bird nesting'' the cable on the drum. ''Bird nesting'' is a condition in which the cable does not wind onto the drum in a uniformly layered manner, but winds in a random fashion where the cable essentially ''piles up'' inappropriately on the drum and, on some occasions, winds on the drum drive shaft. A system to help control this ''bird nesting'' problem has been designed as an addition to the existing components of the Grapple Hoist Assembly. The new design consists of a mechanism that is timed with, and driven by, the shaft that drives the drum. This mechanism traverses back and forth across the width of the drum to lay the cable on the drum in a uniformly layered manner. This test plan establishes the acceptance criteria, test procedure and test conditions It also describes the test apparatus necessary to verify the adequacy of the level wind system design. The test is defined as qualification testing (LMHC 1999b) and as such will be performed at conditions beyond the parameters that the Grapple Hoist Assembly is allowed to operate by the Safety Equipment List (SEL)(LMHC 1998)

  18. Test Plan for Rotary Mode Core Sample Truck Grapple Hoist Level Wind System

    International Nuclear Information System (INIS)

    BOGER, R.M.

    1999-01-01

    A Grapple Hoist Assembly is currently used on the Rotary Mode Core Sampling Trucks (RMCSTs) to actuate the sampler and retrieve the pintle rod during sampling operations. The hoist assembly includes a driven drum approximately two inches wide and six inches in diameter that rotates to pay out or reel in the 5/32-in. cable. The current Grapple Hoist Assembly, detailed on drawing H-2-690057, is prone to ''bird nesting'' the cable on the drum. ''Bird nesting'' is a condition in which the cable does not wind onto the drum in a uniformly layered manner, but winds in a random fashion where the cable essentially ''piles up'' inappropriately on the drum and, on some occasions, winds on the drum drive shaft. A system to help control this ''bird nesting'' problem has been designed as an addition to the existing components of the Grapple Hoist Assembly. The new design consists of a mechanism that is timed with, and driven by, the shaft that drives the drum. This mechanism traverses back and forth across the width of the drum to lay the cable on the drum in a uniformly layered manner. This test plan establishes the acceptance criteria, test procedure and test conditions. It also describes the test apparatus necessary to verify the adequacy of the level wind system design. The test is defined as qualification testing (LMHC 1999b) and as such will be performed at conditions beyond the parameters that the Grapple Hoist Assembly is allowed to operate by the Safety Equipment List

  19. Handbook of technical diagnostics fundamentals and application to structures and systems

    CERN Document Server

    2013-01-01

    This book presents concepts, methods and techniques to examine symptoms of faults and failures of structures, systems and components and to monitor functional performance and structural integrity. The book is organized in five parts. Part A introduces the scope and application of technical diagnostics and gives a comprehensive overview of the physics of failure. Part B presents all relevant methods and techniques for diagnostics and monitoring: from stress, strain, vibration analysis, nondestructive evaluation, thermography and industrial radiology to computed tomography and subsurface microstructural analysis. Part C cores the principles and concepts of technical failure analysis, illustrates case studies, and outlines machinery diagnostics with an emphasis on tribological systems. Part D describes the application of structural health monitoring and performance control to plants and the technical infrastructure, including buildings, bridges, pipelines, electric power stations, offshore wind structures, and r...

  20. Soft x-ray power diagnostic improvements at the Omega Laser Facility

    International Nuclear Information System (INIS)

    Sorce, C.; Schein, J.; Weber, F.; Widmann, K.; Campbell, K.; Dewald, E.; Turner, R.; Landen, O.; Jacoby, K.; Torres, P.; Pellinen, D.

    2006-01-01

    Soft x-ray power diagnostics are essential for evaluating high temperature laser plasma experiments. The Dante soft x-ray spectrometer, a core diagnostic for radiation flux and temperature measurements of Hohlraums, installed on the Omega Laser Facility at the Laboratory for Laser Energetics has recently undergone a series of upgrades. Work performed at Brookhaven National Laboratory for the development of the National Ignition Facility (NIF) Dante spectrometer enables the Omega Dante to offer a total of 18 absolutely calibrated channels in the energy range from 50 eV to 20 keV. This feature provides Dante with the capability to measure higher, NIF relevant, radiation temperatures with increased accuracy including a differentiation of higher energy radiation such as the Au M and L bands. Diagnostic monitoring using experimental data from directly driven Au spherical shots is discussed

  1. Pacific Northwest Laboratory Institutional Plan FY 1995-2000

    Energy Technology Data Exchange (ETDEWEB)

    1994-12-01

    This report serves as a document to describe the role PNL is positioned to take in the Department of Energy`s plans for its national centers in the period 1995-2000. It highlights the strengths of the facilities and personnel present at the laboratory, touches on the accomplishments and projects they have contributed to, and the direction being taken to prepare for the demands to be placed on DOE facilities in the near and far term. It consists of sections titled: director`s statement; laboratory mission and core competencies; laboratory strategic plan; laboratory initiatives; core business areas; critical success factors.

  2. Diagnostic Value of ERG in Prostate Needle Biopsies Containing Minute Cancer Foci

    Directory of Open Access Journals (Sweden)

    Bachurska Svitlana Y.

    2017-03-01

    Full Text Available Background: Prostate carcinoma (PC is the second most diagnosed cancer in men population worldwide. The small amount of the tissue in prostate needle biopsy is often sufficient for the correct interpretation. Novel antibodies, as ERG, could add to the diagnostic value of IHC study in analysing difficult core biopsies.

  3. CT-guided core needle biopsy of mediastinal nodes through a transpulmonary approach: retrospective analysis of the procedures conducted over six years.

    Science.gov (United States)

    Yin, Zhongyuan; Liang, Zhiwen; Li, Pengcheng; Wang, Qiong

    2017-08-01

    To retrospectively evaluate the diagnostic performance and complications of a CT-guided core needle cutting biopsy of mediastinal nodes through a transpulmonary approach. From January 2009 to December 2014, we used a coaxial positioning system and an 18G cutting-type biopsy device to perform CT-guided percutaneous transpulmonary needle biopsies of mediastinal nodes for 127 patients. The diagnostic performance, complication rate, influencing factors, distribution of mediastinal nodes and pathological diagnoses were investigated. Among 127 patients, pathologic analyses showed that all of the biopsies were technically successful. The sensitivity, specificity, positive predictive value, and negative predictive value were all 100%. As for complications, the ratios for pneumothorax and hemoptysis were 33.9% and 4.7%, respectively. Multivariate analyses revealed that the distance from the pleura to the target lesion (P = 0.008) and the numbers of visceral pleura injuries (P = 0.006) were the two most significant risk factors for pneumothorax, and that the distance from the pleura to the target lesion (P = 0.004) was the most significant risk factor for hemoptysis. CT-guided core needle cutting biopsy of mediastinal nodes through a transpulmonary approach is a safe and efficient diagnostic method. • CT-guided core needle biopsy is an accurate technique for diagnosing mediastinal nodes. • The rates of complications are similar to those for pulmonary lesion biopsy. • Pneumothorax risk factors include distance from pleura to target lesion and number of visceral pleura. • Distance from pleura to target lesion is the risk factor for hemoptysis. • CT-guided core needle biopsy is an important diagnostic method for mediastinal nodes.

  4. VERA-CS Verification & Validation Plan

    Energy Technology Data Exchange (ETDEWEB)

    Downar, Thomas [Univ. of Michigan, Ann Arbor, MI (United States)

    2017-02-01

    This report summarizes the current status of VERA-CS Verification and Validation for PWR Core Follow operation and proposes a multi-phase plan for continuing VERA-CS V&V in FY17 and FY18. The proposed plan recognizes the hierarchical nature of a multi-physics code system such as VERA-CS and the importance of first achieving an acceptable level of V&V on each of the single physics codes before focusing on the V&V of the coupled physics solution. The report summarizes the V&V of each of the single physics codes systems currently used for core follow analysis (ie MPACT, CTF, Multigroup Cross Section Generation, and BISON / Fuel Temperature Tables) and proposes specific actions to achieve a uniformly acceptable level of V&V in FY17. The report also recognizes the ongoing development of other codes important for PWR Core Follow (e.g. TIAMAT, MAMBA3D) and proposes Phase II (FY18) VERA-CS V&V activities in which those codes will also reach an acceptable level of V&V. The report then summarizes the current status of VERA-CS multi-physics V&V for PWR Core Follow and the ongoing PWR Core Follow V&V activities for FY17. An automated procedure and output data format is proposed for standardizing the output for core follow calculations and automatically generating tables and figures for the VERA-CS Latex file. A set of acceptance metrics is also proposed for the evaluation and assessment of core follow results that would be used within the script to automatically flag any results which require further analysis or more detailed explanation prior to being added to the VERA-CS validation base. After the Automation Scripts have been completed and tested using BEAVRS, the VERA-CS plan proposes the Watts Bar cycle depletion cases should be performed with the new cross section library and be included in the first draft of the new VERA-CS manual for release at the end of PoR15. Also, within the constraints imposed by the proprietary nature of plant data, as many as possible of the FY17

  5. New Ideas for Confined Alpha Diagnostics on ITER

    Science.gov (United States)

    Fisher, R. K.

    2003-10-01

    Understanding the dynamics of a burning plasma will require development of adequate alpha particle diagnostics. Three new approaches to obtain information on the confined fast alphas in ITER are proposed. The first technique measures the energetic D and T charge exchange (CX) neutrals that result from the alpha collision-induced knock-on fuel ion tails undergoing electron capture on the MeV D neutral beams planned for heating and current drive. CX neutrals with energies >1 ,MeV would be measured to avoid the background due to the large population of injected beam ions. The second technique measures the energetic knock-on neutron tail due to alphas using the lengths of the proton recoil tracks produced by neutron collisions in the film. The range of the 14 to 18 MeV recoil protons increases by ˜400 microns per MeV. The third approach would measure the CX helium neutrals resulting from confined alphas capturing two electrons in the ablation cloud surrounding a dense gas jet that has been proposed for disruption mitigation in ITER. Jet Charge Exchange (JCX) could allow measurements in the plasma core, while the Pellet Charge Exchange (PCX) technique that provided much of the data on confined alphas in TFTR, will likely be limited by pellet penetration to measurements outside r/ a , ˜ ,0.5 in ITER.

  6. Design of new Thomson scattering diagnostic system on COMPASS tokamak

    Czech Academy of Sciences Publication Activity Database

    Bílková, Petra; Aftanas, Milan; Böhm, Petr; Weinzettl, Vladimír; Šesták, David; Melich, Radek; Stöckel, Jan; Scannell, R.; Walsh, M.

    2010-01-01

    Roč. 623, č. 2 (2010), s. 656-659 ISSN 0168-9002. [International Conference on Frontiers in Diagnostic Technologies/1st./. Frascati, 25.11.2009-27.11.2009] R&D Projects: GA ČR GA202/09/1467; GA ČR GD202/08/H057 Institutional research plan: CEZ:AV0Z20430508 Keywords : Thomson scattering * Laser diagnostic * Electron temperature * Electron density Subject RIV: BL - Plasma and Gas Discharge Physics Impact factor: 1.142, year: 2010 www.elsevier.com/locate/nima

  7. Comparison of Battery-Powered and Manual Bone Biopsy Systems for Core Needle Biopsy of Sclerotic Bone Lesions.

    Science.gov (United States)

    Cohen, Micah G; McMahon, Colm J; Kung, Justin W; Wu, Jim S

    2016-05-01

    The purpose of this study was to compare manual and battery-powered bone biopsy systems for diagnostic yield and procedural factors during core needle biopsy of sclerotic bone lesions. A total of 155 consecutive CT-guided core needle biopsies of sclerotic bone lesions were performed at one institution from January 2006 to November 2014. Before March 2012, lesions were biopsied with manual bone drill systems. After March 2012, most biopsies were performed with a battery-powered system and either noncoaxial or coaxial biopsy needles. Diagnostic yield, crush artifact, CT procedure time, procedure radiation dose, conscious sedation dose, and complications were compared between the manual and battery-powered core needle biopsy systems by Fisher exact test and t test. One-way ANOVA was used for subgroup analysis of the two battery-powered systems for procedure time and radiation dose. The diagnostic yield for all sclerotic lesions was 60.0% (93/155) and was significantly higher with the battery-powered system (73.0% [27/37]) than with the manual systems (55.9% [66/118]) (p = 0.047). There was no significant difference between the two systems in terms of crush artifact, procedure time, radiation dose, conscious sedation administered, or complications. In subgroup analysis, the coaxial battery-powered biopsies had shorter procedure times (p = 0.01) and lower radiation doses (p = 0.002) than the coaxial manual systems, but the noncoaxial battery-powered biopsies had longer average procedure times and higher radiation doses than the coaxial manual systems. In biopsy of sclerotic bone lesions, use of a battery-powered bone drill system improves diagnostic yield over use of a manual system.

  8. Experience and evaluation of advanced on-line core monitoring system 'BEACON' at IKATA site

    International Nuclear Information System (INIS)

    Fujitsuka, Nobumichi; Tanouchi, Hideyuki; Imamura, Yasuhiro; Mizobuchil, Daisuke

    1997-01-01

    Shikoku Electric Power Company installed BEACON core monitoring system into IKATA unit 3 in May 1994. During its first cycle of core operation, various operational data were obtained including data of some anomalous reactor conditions introduced for the test objective of the plant start-up. This paper presents the evaluation of the BEACON system capability based on this experience. The system functions such as core monitoring and anomaly detection, prediction of future reactor conditions and increased efficiency of core management activities are discussed. Our future plan to utilize the system is also presented. (authors)

  9. RA reactor action plan for 1977 - Annex VI; Prilog VI - Plan rada reaktora RA za 1977. godinu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1976-12-15

    In the RA reactor action plan for 1977 it is foreseen that the reactor would be operated for 181 days, mostly at nominal power of 6.5 MW. It is planned to produce 28236 MWh in total. Five reactor core exchanges (refuelling) are planned. The plan includes time for repair of components as well as for cooling. [Serbo-Croat] Plan rada reaktora RA predvidja rad tokom 181 dana, vecim delom na nominalnoj snazi od 6,5 MW tokom 1977. godine. Planirano je da ukupni rad iznosi 28236 MWh. Planom je predvidjeno i pet izmena goriva kao i vreme potrebno za remont opreme i hladjenje.

  10. Diagnostic imaging in pregraduate integrated curricula; Radiologie in einem praegraduellen problembasiert-integrierten Medizincurriculum

    Energy Technology Data Exchange (ETDEWEB)

    Kainberger, F.; Kletter, K. [Universitaetsklinik fuer Radiodiagnostik, Medizinische Univ. Wien (Austria)

    2007-11-15

    Pregraduate medical curricula are currently undergoing a reform process that is moving away from a traditional discipline-related structure and towards problem-based integrated forms of teaching. Imaging sciences, with their inherently technical advances, are specifically influenced by the effects of paradigm shifts in medical education. The teaching of diagnostic radiology should be based on the definition of three core competencies: in vivo visualization of normal and abnormal morphology and function, diagnostic reasoning, and interventional treatment. On the basis of these goals, adequate teaching methods and e-learning tools should be implemented by focusing on case-based teaching. Teaching materials used in the fields of normal anatomy, pathology, and clinical diagnosis may help diagnostic radiology to play a central role in modern pregraduate curricula. (orig.)

  11. Finding optimal measures of core inflation in the Kyrgyz Republic

    Czech Academy of Sciences Publication Activity Database

    Uzagalieva, Ainura

    -, č. 261 (2005), s. 1-37 ISSN 1211-3298 Institutional research plan: CEZ:AV0Z70850503 Keywords : Kyrgyz Republic * core inflation * monetary policy Subject RIV: AH - Economics http://www.cerge-ei.cz/pdf/wp/Wp261.pdf

  12. The role of femoroacetabular impingement in core muscle injury/athletic pubalgia: diagnosis and management

    Directory of Open Access Journals (Sweden)

    Thomas eEllis

    2016-02-01

    Full Text Available Chronic groin pain in athletes represents a major diagnostic and therapeutic challenge in sports medicine. Two recognized causes of inguinal pain in the young adult athlete are core muscle injury/athletic pubalgia (CMI/AP and femoroacetabular impingement (FAI. CMI/AP and FAI were previously considered to be two distinct entities, however recent studies have suggested both entities to frequently coincide in the athlete with groin pain. This article briefly discusses the role of femoroacetabular impingement in core muscle injury/athletic pubalgia, and the diagnosis and management of this complex disease.

  13. Multi-Directional Optical Diagnostics of Thermal Plasma Jets

    Czech Academy of Sciences Publication Activity Database

    Hlína, Jan; Chvála, František; Šonský, Jiří; Gruber, Jan

    2008-01-01

    Roč. 19, č. 1 (2008), s. 1-6 ISSN 0957-0233 R&D Projects: GA ČR(CZ) GA202/05/0728 Institutional research plan: CEZ:AV0Z20570509 Keywords : thermal plasma jet * optical diagnostics * Radon transform Subject RIV: BL - Plasma and Gas Discharge Physics Impact factor: 1.493, year: 2008

  14. DIAGNOSTICS FOR ION BEAM DRIVEN HIGH ENERGY DENSITY PHYSICS EXPERIMENTS

    International Nuclear Information System (INIS)

    Bieniosek, F.M.; Henestroza, E.; Lidia, S.; Ni, P.A.

    2010-01-01

    Intense beams of heavy ions are capable of heating volumetric samples of matter to high energy density. Experiments are performed on the resulting warm dense matter (WDM) at the NDCX-I ion beam accelerator. The 0.3 MeV, 30-mA K + beam from NDCX-I heats foil targets by combined longitudinal and transverse neutralized drift compression of the ion beam. Both the compressed and uncompressed parts of the NDCX-I beam heat targets. The exotic state of matter (WDM) in these experiments requires specialized diagnostic techniques. We have developed a target chamber and fielded target diagnostics including a fast multi-channel optical pyrometer, optical streak camera, laser Doppler-shift interferometer (VISAR), beam transmission diagnostics, and high-speed gated cameras. We also present plans and opportunities for diagnostic development and a new target chamber for NDCX-II.

  15. Heat removal capability of core-catcher with inclined cooling channels

    International Nuclear Information System (INIS)

    Suzuki, Y.; Tahara, M.; Kurita, T.; Hamazaki, R.; Morooka, S.

    2009-01-01

    A core-catcher is one of the mitigation systems that provide functions of molten corium cooling and stabilization during a severe accident. Toshiba has been developing a compact core-catcher to be placed at the lower drywell floor in the containment vessel for the next generation BWR as well as near term ABWR. This paper presents the evaluation of heat removal capability of the core-catcher with inclined cooling channels, our verification status and plan. The heat removal capability of the core-catcher is analyzed by using the newly developed two-phase flow analysis code which incorporates drift flux parameters for inclined channels and the CHF correlation obtained from SULTAN tests. Effects of geometrical parameters such as the inclination and the gap size of the cooling channel on the heat removal capability are also evaluated. These results show that the core-catcher has sufficient capability to cool the molten corium during a severe accident. Based on the analysis, it has been shown that the core-catcher has an efficient capability of heat removal to cool the molten corium. (author)

  16. Ultrasound-guided core needle biopsy in diagnosis of abdominal and pelvic neoplasm in pediatric patients.

    Science.gov (United States)

    Wang, Hailing; Li, Fangxuan; Liu, Juntian; Zhang, Sheng

    2014-01-01

    Ultrasound-guided core needle biopsy of abdominal and pelvic masses in adults has gained tremendous popularity. However, the application of the same treatment in children is not as popular because of apprehensions regarding inadequate tissues for the biopsy and accidental puncture of vital organs. Data of the application of ultrasound-guided core needle biopsy in 105 pediatric patients with clinically or ultrasound-diagnosed abdominopelvic masses were reviewed. Diagnostic procedures were conducted in our institution from May 2011 to May 2013. The biopsies were conducted on 86 malignant lesions and 19 benign lesions. 86 malignant tumors comprised neuroblastomas (30 cases), hepatoblastomas (15 cases), nephroblastomas (11 cases), and primitive neuroectodermal tumors/malignant small round cells (6 cases). Among malignant tumor cases, only a pelvic primitive neuroectodermal tumor did not receive a pathological diagnosis. Therefore, the biopsy accuracy was 98.8 % in malignant tumor. However, the biopsies for one neuroblastomas and one malignant small round cell tumor were inadequate for cytogenetic analysis. Therefore, 96.5 % of the malignant tumor patients received complete diagnosis via biopsy. 19 benign tumors comprised mature teratoma (10 cases), hemangioendothelioma (3 cases), paraganglioma (2 cases), and infection (2 cases). The diagnostic accuracy for benign neoplasm was 100 %. Five patients experienced postoperative complications, including pain (2 patients), bleeding from the biopsy site (2 patients), and wound infection (1 patient). Ultrasound-guided core needle biopsy is an efficient, minimally invasive, accurate, and safe diagnostic method that can be applied in the management of abdominal or pelvic mass of pediatric patients.

  17. Measurement of core plasma temperature and rotation on W7-X made available by the x-ray imaging crystal spectrometer (XICS)

    Energy Technology Data Exchange (ETDEWEB)

    Pablant, N A; Bitter, M; Burhenn, R; Delgado-Aparicio, L; Ellis, R; Gates, D; Goto, M; Hill, K W; Langenberg, A; Lazerson, S; Mardenfeld, M; Morita, S; Neilson, G H; Oishi, T; Pedersen, T S

    2014-07-01

    A new x-ray imaging crystal spectrometer diagnostic (XICS) is currently being built for installation on W7-X. This diagnostic will contribute to the study of ion and electron thermal transport and the evolution of the radial electric field by providing high resolution temperature and rotation measurements under many plasma conditions, including ECH heated plasmas. Installation is expected before the first experimental campaign (OP1.1), making an important set of measurements available for the first W7-X plasmas. This diagnostic will also work in concert with the HR-XCS diagnostic to provide an excellent diagnostic set for core impurity transport on W7-X.

  18. Engineering review of the core support structure of the Gas Cooled Fast Breeder Reactor

    International Nuclear Information System (INIS)

    1978-09-01

    The review of the core support structure of the gas cooled fast breeder reactor (GCFR) covered such areas as the design criteria, the design and analysis of the concepts, the development plan, and the projected manufacturing costs. Recommendations are provided to establish a basis for future work on the GCFR core support structure

  19. Diagnostic reasoning strategies and diagnostic success.

    Science.gov (United States)

    Coderre, S; Mandin, H; Harasym, P H; Fick, G H

    2003-08-01

    Cognitive psychology research supports the notion that experts use mental frameworks or "schemes", both to organize knowledge in memory and to solve clinical problems. The central purpose of this study was to determine the relationship between problem-solving strategies and the likelihood of diagnostic success. Think-aloud protocols were collected to determine the diagnostic reasoning used by experts and non-experts when attempting to diagnose clinical presentations in gastroenterology. Using logistic regression analysis, the study found that there is a relationship between diagnostic reasoning strategy and the likelihood of diagnostic success. Compared to hypothetico-deductive reasoning, the odds of diagnostic success were significantly greater when subjects used the diagnostic strategies of pattern recognition and scheme-inductive reasoning. Two other factors emerged as independent determinants of diagnostic success: expertise and clinical presentation. Not surprisingly, experts outperformed novices, while the content area of the clinical cases in each of the four clinical presentations demonstrated varying degrees of difficulty and thus diagnostic success. These findings have significant implications for medical educators. It supports the introduction of "schemes" as a means of enhancing memory organization and improving diagnostic success.

  20. A near-infrared spectroscopic study of the starburst core of M82

    International Nuclear Information System (INIS)

    Lester, D.F.; Gaffney, N.; Carr, J.S.; Joy, M.

    1990-01-01

    Near-IR spectroscopy of the M82 starburst core is presented, including complete J, H, and K band spectra with a resolution of 0.0035-micron for the inner 60 pc of the galaxy. Also, spatial profiles along the starburst ridge are presented for Br-gamma, molecular hydrogen, and forbidden Fe II line fluxes. Emission from shocked molecular hydrogen is detected from the core of M82. The distribution of features across the starburst disk are mapped to study the relationships between spectral diagnostics. The observations are used to test the appropriateness of single-beam, aggregate models for studying the physical conditions in starbursts. 68 refs

  1. A near-infrared spectroscopic study of the starburst core of M82

    Science.gov (United States)

    Lester, D. F.; Gaffney, N.; Carr, J. S.; Joy, M.

    1990-01-01

    Near-IR spectroscopy of the M82 starburst core is presented, including complete J, H, and K band spectra with a resolution of 0.0035-micron for the inner 60 pc of the galaxy. Also, spatial profiles along the starburst ridge are presented for Br-gamma, molecular hydrogen, and forbidden Fe II line fluxes. Emission from shocked molecular hydrogen is detected from the core of M82. The distribution of features across the starburst disk are mapped to study the relationships between spectral diagnostics. The observations are used to test the appropriateness of single-beam, aggregate models for studying the physical conditions in starbursts.

  2. [Dealing with diagnostic uncertainty in general practice].

    Science.gov (United States)

    Wübken, Magdalena; Oswald, Jana; Schneider, Antonius

    2013-01-01

    In general, the prevalence of diseases is low in primary care. Therefore, the positive predictive value of diagnostic tests is lower than in hospitals where patients are highly selected. In addition, the patients present with milder forms of disease; and many diseases might hide behind the initial symptom(s). These facts lead to diagnostic uncertainty which is somewhat inherent to general practice. This narrative review discusses different sources of and reasons for uncertainty and strategies to deal with it in the context of the current literature. Fear of uncertainty correlates with higher diagnostic activities. The attitude towards uncertainty correlates with the choice of medical speciality by vocational trainees or medical students. An intolerance of uncertainty, which still increases as medicine is making steady progress, might partly explain the growing shortage of general practitioners. The bio-psycho-social context appears to be important to diagnostic decision-making. The effect of intuition and heuristics are investigated by cognitive psychologists. It is still unclear whether these aspects are prone to bias or useful, which might depend on the context of medical decisions. Good communication is of great importance to share uncertainty with the patients in a transparent way and to alleviate shared decision-making. Dealing with uncertainty should be seen as an important core component of general practice and needs to be investigated in more detail to improve the respective medical decisions. Copyright © 2013. Published by Elsevier GmbH.

  3. Approval plans issues and innovations

    CERN Document Server

    Katz, Linda S

    2013-01-01

    How can you, as an acquisition librarians, keep current on the output of hundreds of publishers? The answer, of course, is that you cannot. For over 30 years, approval plans have been used by librarians to acquire current titles, save staff time, and build core collections. Even today, these reasons seem appropriate, as libraries try to maintain up-to-date collections and control personnel and operating budgets. However, as shown in Approval Plans: Issues and Innovations, the use of approval plans is not so simple and straightforward; their use is subject to complex procedures and policies--an

  4. The core to regulatory reform

    International Nuclear Information System (INIS)

    Partridge, J.W. Jr.

    1993-01-01

    Federal Energy Regulatory Commission (FERC) Orders 436, 500, and 636, the Clean Air Act Amendments of 1990, Public Utility Holding Company Act reform, and the 1992 Energy Policy Act all can have significant effects on an LDC's operations. Such changes in an LDC's environments must be balanced by changes within the utility, its marketplace, and its state regulatory environment. The question is where to start. For Columbia Gas Distribution Cos., based in Columbus, OH, the new operating foundation begins with each employee. Internal strength is critical in designing initiatives that meet the needs of the marketplace and are well-received by regulators. Employees must understand not only the regulatory environment in which the LDC operates, but also how their work contributes to a positive regulatory relationship. To achieve this, Columbia initiated the COntinuing Regulatory Education program, or CORE, in 1991. CORE is a regulatory-focused, information-initiative program coordinated by Columbia's Regulatory Policy, Planning, and Government Affairs Department. The CORE programs can take many forms, such as emerging issue discussions, dialogues with regulators and key parties, updates on regulatory fillings, regulatory policy meetings, and formal training classes. The speakers and discussion facilitators can range from human resource department trainers to senior officers, from regulatory department staff members to external experts, or from state commissioners to executives from other LDCs. The goals of CORE initiatives are to: Support a professional level of regulatory expertise through employee participation in well-developed regulatory programs presented by credible experts. Encourage a constructive state regulatory environment founded on communication and cooperation. CORE achieves these goals via five program levels: introductory basics, advanced learning, professional expertise, crossfunctional dialogues, and external idea exchanges

  5. Analysis of the priority of anatomic structures according to the diagnostic task in cone-beam computed tomographic images

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Jin Woo [Dept. of Oral and Maxillofacial Radiology, Dankook University College of Dentistry, Chunan (Korea, Republic of)

    2016-12-15

    This study was designed to evaluate differences in the required visibility of anatomic structures according to the diagnostic tasks of implant planning and periapical diagnosis. Images of a real skull phantom were acquired under 24 combinations of different exposure conditions in a cone-beam computed tomography scanner (60, 70, 80, 90, 100, and 110 kV and 4, 6, 8, and 10 mA). Five radiologists evaluated the visibility of anatomic structures and the image quality for diagnostic tasks using a 6-point scale. The visibility of the periodontal ligament space showed the closest association with the ability to use an image for periapical diagnosis in both jaws. The visibility of the sinus floor and canal wall showed the closest association with the ability to use an image for implant planning. Variations in tube voltage were associated with significant differences in image quality for all diagnostic tasks. However, tube current did not show significant associations with the ability to use an image for implant planning. The required visibility of anatomic structures varied depending on the diagnostic task. Tube voltage was a more important exposure parameter for image quality than tube current. Different settings should be used for optimization and image quality evaluation depending on the diagnostic task.

  6. Institutional plan. FY 1997-2002

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-06-01

    The FY 1997-2002 Institutional Plan provides an overview of the Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab) mission, strategic plan, core business areas, critical success factors, and the resource requirements to fulfill its mission in support of national needs in fundamental science and technology, energy resources, and environmental quality. Of particular significance this year is the role of computing sciences in supporting a broad range of research activities, at Berkeley Lab in particular and throughout the entire Department of Energy system in general. The Institutional Plan is a management report for integration with the Department of Energy`s mission and programs and is an element of Department of Energy`s strategic management planning activities, developed through an annual planning process. The plan identifies technical and administrative directions in the context of the national energy policy and research needs and the Department of Energy`s program planning initiatives.

  7. [Modifications in health and welfare jobs transferred to thirty-five participating "core cities"].

    Science.gov (United States)

    Hara, Kunio; Hoshiko, Michiko; Ishitake, Tatsuya

    2010-06-01

    The aim of this study was to determine modifications in health and welfare jobs transferred to thirty-five participating "core cities. We focused on health and welfare jobs in the following sectors: (1) local welfare; (2) health care; (3) city planning; (4) environmental protection; (5) education; and (6) urban revitalization. We developed a self-report questionnaire regarding implementation of administrative jobs transferred from prefectures to the core cities with attention to affects of changes in the jobs on the city administrative efficiency and the health of both the citizens and the city officials. The questionnaire, consisting of 27 multiple-choice and 12 open-ended questions, was forwarded via e-mail to lead city officials of the thirty-five core cities in mid-February 2008. Twenty-seven cities responded to the questionnaire in mid-March 2008 (collection rate: 77%). The core cities incorporated almost all the jobs transferred from the prefectures, in spite of some limitations regarding time taken for delivering assistive equipment to disabled children, implementing wider administrative plans and establishing educational centers. Almost all core cities answered that they implemented their jobs independently, autonomously and systematically. Seventeen out of 27 core cities established new health care centers during the transition period and increased their number of staff. The majority of these 17 answered that establishment of organizations directly providing services to citizens contributed to improvement in the efficiency of the administrative jobs. The core cities incorporated almost all the jobs transferred from the prefectures in spite of some limitations. The core cities which established their new health care centers during this transition period increased their number of staff to address modifications to the work load.

  8. Cancer physics: diagnostics based on damped cellular elastoelectrical vibrations in microtubules.

    Science.gov (United States)

    Pokorný, Jiří; Vedruccio, Clarbruno; Cifra, Michal; Kučera, Ondřej

    2011-06-01

    This paper describes a proposed biophysical mechanism of a novel diagnostic method for cancer detection developed recently by Vedruccio. The diagnostic method is based on frequency selective absorption of electromagnetic waves by malignant tumors. Cancer is connected with mitochondrial malfunction (the Warburg effect) suggesting disrupted physical mechanisms. In addition to decreased energy conversion and nonutilized energy efflux, mitochondrial malfunction is accompanied by other negative effects in the cell. Diminished proton space charge layer and the static electric field around the outer membrane result in a lowered ordering level of cellular water and increased damping of microtubule-based cellular elastoelectrical vibration states. These changes manifest themselves in a dip in the amplitude of the signal with the fundamental frequency of the nonlinear microwave oscillator-the core of the diagnostic device-when coupled to the investigated cancerous tissue via the near-field. The dip is not present in the case of healthy tissue.

  9. Whole-core LEU fuel demonstration in the ORR

    International Nuclear Information System (INIS)

    Snelgrove, J.L.; Bretscher, M.M.; Cornella, R.J.; Hobbs, R.W.

    1985-01-01

    A whole-core demonstration of LEU fuel in the ORR is expected to begin during November 1985. Fuel elements will contain U 3 Si 2 at 4.8 Mg U/m 3 and shim rod fuel followers will contain U 3 Si 2 at 3.5 Mg U/m 3 . Fuel fabrication is underway at B and W, CERCA, and NUKEM, with shipments scheduled to commence in October. The primary objectives of the demonstration are to provide data for validation of LEU and mixed-core fuel cycle calculations and to provide a large-scale demonstration of the acceptable performance of production-line U 3 Si 2 fuel elements. It is planned to approach the full LEU core through a series of mixed cores. Measurements to be made include flux distribution, reactivity swing, control rod worths, cycle length, fuel discharge burnup, gamma heating rates, β/sub eff/l, and isothermal temperature coefficient. Measurements will also be made on fresh LEU and fresh HEU critical configurations. Preliminary safety approval has been received and the final safety assessment is being reviewed

  10. NETWORK SERVICES FOR DIAGNOSTIC OPTODIGITAL COMPLEX FOR TELEMEDICINE

    Directory of Open Access Journals (Sweden)

    D. S. Kopylov

    2014-03-01

    Full Text Available The paper deals with a result of the network services development for the optodigital complex for telemedicine diagnostics. This complex is designed for laboratory and clinical tests in health care facilities. Composition of network services includes the following: a client application for database of diagnostic test, a web-service, a web interface, a video server and microimage processing server. Structure of these services makes it possible to combine set of software for transferring depersonalized medical data via the Internet and operating with optodigital devices included in the complex. Complex is consisted of three systems: micro-vision, endoscopic and network. The micro-vision system includes an automated digital microscope with two highly sensitive cameras which can be controlled remotely via the Internet. The endoscopic system gives the possibility to implement video broadcasting to remote users both during diagnostic tests and also off-line after tests. The network system is the core of the complex where network services and application software are functioning, intended for archiving, storage and providing access to the database of diagnostic tests. The following subjects are developed and tested for functional stability: states transfer protocol, commands transfer protocol and video-stream transfer protocol from automated digital microscope and video endoscope. These protocols can work in web browsers on modern mobile devices without additional software.

  11. A study of passive safety conditions for fast reactor core

    International Nuclear Information System (INIS)

    Shimizu, Akinao

    1991-01-01

    A study has been made for passive safety conditions of fast reactor cores. Objective of the study is to develop a concept of a core with passive safety as well as a simple safety philosophy. A simple safety philosophy, which is wore easy to explain to the public, is needed to enhance the public acceptance for nuclear reactors. The present paper describes a conceptual plan of the study including the definition of the problem a method of approach and identification of tasks to be solved

  12. Experiences with 'on-line' diagnostic instrumentation in nuclear power plants

    International Nuclear Information System (INIS)

    Gopal, R.; Ciaramitaro, W.; Smith, J.R.

    1981-01-01

    Over the past several years, Westinghouse has developed a coordinated system of on-line diagnostic instrumentation for the acquisition and analysis of data for diagnostics and incipient failure detection of critical plant equipment and systems. Primary motivation for this work is to improve Nuclear Steam Supply System (NSSS) availability and maintainability through the detection of malfunctions at their inception. These systems include: 1) Acoustic leak monitoring for detection and location of leaks in the primary system pressure boundary and other piping systems in PWR's; 2) Metal impact monitoring for detection of loose debris in the reactor vessel and steam generators; 3) Nuclear noise monitoring for monitoring core barrel vibration. Summarized in this paper are some of the features of the systems and inplant experience. (author)

  13. Opacity in compact extragalactic radio sources and the core shift effect

    International Nuclear Information System (INIS)

    Kovalev, Y Y; Lobanov, A P; Pushkarev, A B; Zensus, J A

    2008-01-01

    The apparent position of the 'core' in a parsec-scale radio jet (a compact, bright emitting region at the narrow end of the jet) depends on the observing frequency, owing to synchrotron self-absorption and external absorption. This dependency both provides a tool to probe physical conditions in the vicinity of the core and poses problems for astrometric studies using compact radio sources. We investigate the frequency-dependent shift of the positions of the cores (core shift) observed with very long baseline interferometry (VLBI) in parsec-scale jets. We present results for 29 selected active galactic nuclei (AGN). In these AGN, the magnitude of the measured core shift between 2.3 and 8.6 GHz reaches 1.4 mas, with a median value for the sample of 0.44 mas. We discuss related physics as well as astrometry applications and plans for further studies.

  14. Oak Ridge National Laboratory Institutional Plan, FY 1995--FY 2000

    Energy Technology Data Exchange (ETDEWEB)

    1994-11-01

    This report discusses the institutional plan for Oak Ridge National Laboratory for the next five years (1995-2000). Included in this report are the: laboratory director`s statement; laboratory mission, vision, and core competencies; laboratory plan; major laboratory initiatives; scientific and technical programs; critical success factors; summaries of other plans; and resource projections.

  15. Test Plan for Rotary Mode Core Sample Truck Grapple Hoist Level Wind System

    Energy Technology Data Exchange (ETDEWEB)

    BOGER, R.M.

    1999-12-09

    A Grapple Hoist Assembly is currently used on the Rotary Mode Core Sampling Trucks (RMCSTs) to actuate the sampler and retrieve the pintle rod during sampling operations. The hoist assembly includes a driven drum approximately two inches wide and six inches in diameter that rotates to pay out or reel in the 5/32-in. cable The current Grapple Hoist Assembly, detailed on drawing H-2-690057, is prone to ''bird nesting'' the cable on the drum. ''Bird nesting'' is a condition in which the cable does not wind onto the drum in a uniformly layered manner, but winds in a random fashion where the cable essentially ''piles up'' inappropriately on the drum and, on some occasions, winds on the drum drive shaft. A system to help control this ''bird nesting'' problem has been designed as an addition to the existing components of the Grapple Hoist Assembly. The new design consists of a mechanism that is timed with, and driven by, the shaft that drives the drum. This mechanism traverses back and forth across the width of the drum to lay the cable on the drum in a uniformly layered manner. This test plan establishes the acceptance criteria, test procedure and test conditions It also describes the test apparatus necessary to verify the adequacy of the level wind system design. The test is defined as qualification testing (LMHC 1999b) and as such will be performed at conditions beyond the parameters that the Grapple Hoist Assembly is allowed to operate by the Safety Equipment List (SEL)(LMHC 1998).

  16. Experience with diagnostic instrumentation in nuclear power plants

    International Nuclear Information System (INIS)

    Gopal, R.; Ciaramitaro, W.

    1977-01-01

    Over the past several years, Westinghouse has developed a coordinated system of on-line diagnostic instrumentation for the acquisition and analysis of data for diagnostics and incipient failure detection of critical plant equipment and systems. Primary motivation for this work is to improve NSSS availability and Maintainability through the detection of malfunctions at their inception. These systems encompass the following areas: (1) Vibration Monitoring System for detection of changes in vibrational characteristics of the major components of Nuclear Steam Supply System (NSSS) and Balance of Plant (BOP); (2) Acoustic Monitoring System for detection and location of leaks in the primary system pressure boundary and other piping systems in PWRs; (3) Metal Impact Monitoring for detection of loose debris in the reactor vessel and steam generators; (4) Nuclear Noise Monitoring System for monitoring core barrel vibration; (5) Sensor Response Time Measurement System for detecting any degradation of process sensors; and (6) Transit Time Flow Meter for determining primary coolant flow rate. Summarized in this paper are some of the features of the systems and in-plant experience. These experiences demonstrate that diagnostic systems in combination with analytical and laboratory work for data interpretation do improve plant availability. (author)

  17. Construction of the HTTR in-core components

    International Nuclear Information System (INIS)

    Maruyama, S.; Saikusa, A.; Shiozawa, S.; Tsuji, N.; Jinza, K.; Miki, T.

    1996-01-01

    The reactor internals of HTTR consist of graphite and metallic core support structures and shielding blocks and are designed to support core elements and to shield neutron fluence. They also have functions to restrict by-pass flow for ensuring the core cooling performance and to maintain the temperature of metallic core support structures within their design limits. The detailed design of the HTTR core support structure was approved by the government through safety review, 1990-1991. Machining of all graphite components, which consist of about 150 large blocks, was finished in September 1994 successfully. Machining and fabricating of the metallic components were also finished in September. Prior to their installation in the reactor pressure vessel (RPV), the assembly test of actual reactor internals was performed at the works to confirm above mentioned functions. The assembly test was conducted by examining fabricating precision of each component and alignment of piled-up structures, measuring circumferential coolant velocity profile in the passage between the RPV and reactor internals as well as under the core support plates with respect to structural integrity, and measuring by-pass flow rate through gaps between graphite components which may degrade core performance. The another purpose of the assembly test was to confirm the installation procedure of those components. All components were assembled at the works according to the planned procedure, and the tests were executed while assembling. As a result of the tests, measured level difference and gap width between reactor internals were negligible from core thermal and hydraulic performance point of view. Coolant flows uniformly in circumferential direction at any axial level in the RPV. By-pass flow rate was found to be suppressed sufficiently and far less than the design limit. (J.P.N.)

  18. Chesapeake Bay Impact Structure Deep Drilling Project Completes Coring

    Directory of Open Access Journals (Sweden)

    the Scientific Staff of the Chesapeake Bay Impact Structure Deep Drilling Project

    2006-09-01

    Full Text Available The Chesapeake Bay Impact Structure Deep Drilling Project (CBIS Project completed its coring operations during September–December 2005 and April–May 2006. Cores were collected continuously to a total depth of 1766 m. The recovered section consists of 1322 m of impactites beneath 444 m of post-impact continental shelf sediments.The CBIS Project is a joint venture of the International Continental Scientifi c Drilling Program (ICDP and the U.S. Geological Survey (USGS. Project activities began with a planning workshop in September 2003 attended by sixtythree scientists from ten countries. Field operations began with site preparation in July 2005, and coring began in September 2005. Drilling, Observation and Sampling of theEarth’s Continental Crust (DOSECC was the general contractor for the drilling operations throughout 2005.

  19. Diagnostic Risk Adjustment for Medicaid: The Disability Payment System

    Science.gov (United States)

    Kronick, Richard; Dreyfus, Tony; Lee, Lora; Zhou, Zhiyuan

    1996-01-01

    This article describes a system of diagnostic categories that Medicaid programs can use for adjusting capitation payments to health plans that enroll people with disability. Medicaid claims from Colorado, Michigan, Missouri, New York, and Ohio are analyzed to demonstrate that the greater predictability of costs among people with disabilities makes risk adjustment more feasible than for a general population and more critical to creating health systems for people with disability. The application of our diagnostic categories to State claims data is described, including estimated effects on subsequent-year costs of various diagnoses. The challenges of implementing adjustment by diagnosis are explored. PMID:10172665

  20. Wide-view charge exchange recombination spectroscopy diagnostic for Alcator C-Moda)

    Science.gov (United States)

    Rowan, W. L.; Bespamyatnov, I. O.; Granetz, R. S.

    2008-10-01

    This diagnostic measures temperature, density, and rotation for the fully stripped boron ion between the pedestal top and the plasma core with resolution consistent with the profile gradients. The diagnostic neutral beam used for the measurements generates a 50 keV, 6 A hydrogen beam. The optical systems provide views in both poloidal and toroidal directions. The imaging spectrometer is optimized to simultaneously accept 45 views as input with minimum cross-talk. In situ calibration techniques are applied for spatial location, spectral intensity, and wavelength. In the analysis, measured spectra are fitted to a model constructed from a detailed description of the emission physics. Methods for removal of interfering spectra are included. Applications include impurity and thermal transport.

  1. Action plan for 1965, Annex 2; Prilog br. 2 - Plan zadataka u 1965. godini

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1965-12-15

    Action plan presented in this annex includes tasks of the mechanics, electrical and electronic equipment services. It includes a detailed list of planned and preventive maintenance actions related to the heavy water system, technical water system, helium system, reactor core, transportation equipment, hot cells, heating and ventilation systems in the reactor building, power supply system, auxiliary systems in the RA reactor building. [Serbo-Croat] Plan zadataka obuhvata aktivnosti masinske i elektro grupe na preventivnom odrzavanju i planskom remontu sistema teske vode, sistema tehnicke vode, sistema helijuma, centralnog tela reaktora, sistema grejanja i ventilacije, sistema za snabdevanje elektricnom energijom, i ostalih pomocnih sistema u zgradi reaktora RA.

  2. Core of Coalition Games on MV-algebras

    Czech Academy of Sciences Publication Activity Database

    Kroupa, Tomáš

    2011-01-01

    Roč. 21, č. 3 (2011), s. 479-492 ISSN 0955-792X R&D Projects: GA MŠk 1M0572; GA ČR GA102/08/0567 Institutional research plan: CEZ:AV0Z10750506 Keywords : coalition game * core * MV-algebra Subject RIV: BA - General Mathematics Impact factor: 0.611, year: 2011 http://library.utia.cas.cz/separaty/2011/MTR/kroupa-0359839.pdf

  3. CT-guided percutaneous core needle biopsy in deep seated musculoskeletal lesions: a prospective study of 128 cases

    International Nuclear Information System (INIS)

    Puri, A.; Shingade, V.U.; Agarwal, M.G.; Anchan, C.; Juvekar, S.; Desai, S.; Jambhekar, N.A.

    2006-01-01

    28 were inconclusive (diagnostic yield of 79.41%). Of 108 diagnostic biopsies, five were considered inaccurate (accuracy rate of 95.37%). The overall diagnostic yield and accuracy rate for bony lesions were 81.03% and 95.74%; and those for soft-tissue lesions were 70% and 92.85%. There were two complications with no permanent sequelae. CT-guided core needle biopsy is a safe, easy, and effective technique for the evaluation of deep-seated musculoskeletal lesions, with a high rate of diagnostic yield and accuracy. It facilitates definitive therapy without the patient having to undergo a major surgical procedure for diagnosis. (orig.)

  4. Thematic report on urban energy planning

    DEFF Research Database (Denmark)

    Meijers, Evert; Romein, Arie; Stead, Dominic

    The report reviews relations between urban structure (spatial structure + institutional structure) and four core themes of urban energy: • Urban planning and energy use in buildings (mainly residential buildings) • Industrial energy use and urban form • Spatial Planning, Urban Form and Transport...... Energy Consumption • Urban energy generation The reports ends with a summary of potential measure and policies of spatial planning in each of the four themes. However, we highlight also that it is crucial to consider the wider perspective and include considerations of potential rebound effects on direct...

  5. Earth's core convection: Boussinesq approximation or incompressible approach?

    Czech Academy of Sciences Publication Activity Database

    Anufriev, A. P.; Hejda, Pavel

    2010-01-01

    Roč. 104, č. 1 (2010), s. 65-83 ISSN 0309-1929 R&D Projects: GA AV ČR IAA300120704 Grant - others:INTAS(XE) 03-51-5807 Institutional research plan: CEZ:AV0Z30120515 Keywords : geodynamic models * core convection * Boussinesq approximation Subject RIV: DE - Earth Magnetism, Geodesy, Geography Impact factor: 0.831, year: 2010

  6. Core Support of the Board on Mathematical Sciences

    Energy Technology Data Exchange (ETDEWEB)

    None

    1995-04-04

    This proposal summarizes activities conducted by the Board on Mathematical Sciences (BMS) during the period August 1, 1994 to July 31, 1995 and describes future plans of the Board for the period August 1, 1995 to July 31, 1998. We are requesting core support in the amount of $105,000 ($35,000 each year) from the Department of Energy for the additional three-year period. The BMS activities supported exclusively by core funding are the annual Department Chairs Colloquia, the National Science and Technology Symposia, specific reports, the initiation of all projects, continuous oversight of all activities, and partial core support of the Committee on Applied and Theoretical Statistics (CATS). Other activities of the Board include giving recommendations on research directions to federal agencies, and reports on education in the mathematical sciences, interaction of mathematical sciences with other areas, health of the mathematical sciences, and emerging research directions.

  7. The whole-core LEU fuel demonstration in the ORR

    International Nuclear Information System (INIS)

    Snelgrove, J.L.; Bretscher, M.M.; Cornella, R.J.; Hobbs, R.W.

    1985-01-01

    A whole-core demonstration of LEU fuel in the ORR is expected to begin during November 1985. Fuel elements will contain U 3 Si 2 at 4.8 Mg U/m 3 and shim rod fuel followers will contain U 3 Si 2 at 3.5 Mg U/m 3 . Fuel fabrication is underway at B and W, CERCA, and NUKEM, with shipments scheduled to commence in October. The primary objectives of the demonstration are to provide data for validation of LEU and mixed-core fuel cycle calculations and to provide a large-scale demonstration of the acceptable performance of production-line U 3 Si 2 fuel elements. It is planned to approach the full LEU core through a series of mixed cores. Measurements to be made include flux distribution, reactivity swing, control rod worth, cycle length, fuel discharge burn-up, gamma heating rate, β eff /l, and isothermal temperature coefficient. Measurements will also be made on fresh LEU and fresh HEU critical configurations. Preliminary safety approval has been received and the final safety assessment is being reviewed. Key issues being addressed in the safety assessment are fuel performance, radiological consequences, margin to burnout and transient behavior. The LEU core is comparable in all safety aspects to the HEU core and the transition core is only marginally worse owing to higher power seeking factors. (author)

  8. Examining the Common Core State Standards in Agricultural Education

    Science.gov (United States)

    McKim, Aaron J.; Lambert, Misty D.; Sorensen, Tyson J.; Velez, Jonathan J.

    2015-01-01

    The Common Core State Standards (CCSS) represent a shift in the American education system. Included in the CCSS are opportunities for agriculture teachers to integrate math and English language arts content into their curriculum. Using the theory of planned behavior, we sought to identify Oregon agriculture teachers' attitudes, familiarity with,…

  9. Image registration: An essential part of radiation therapy treatment planning

    International Nuclear Information System (INIS)

    Rosenman, Julian G.; Miller, Elizabeth P.; Tracton, Gregg; Cullip, Tim J.

    1998-01-01

    Purpose: We believe that a three-dimensional (3D) registration of nonplanning (diagnostic) imaging data with the planning computed tomography (CT) offers a substantial improvement in tumor target identification for many radiation therapy patients. The purpose of this article is to review and discuss our experience to date. Methods and Materials: We reviewed the charts and treatment planning records of all patients that underwent 3D radiation treatment planning in our department from June 1994 to December 1995, to learn which patients had image registration performed and why it was thought they would benefit from this approach. We also measured how much error would have been introduced into the target definition if the nonplanning imaging data had not been available and only the planning CT had been used. Results: Between June 1994 and December 1995, 106 of 246 (43%) of patients undergoing 3D treatment planning had image registration. Four reasons for performing registration were identified. First, some tumor volumes have better definition on magnetic resonance imaging (MRI) than on CT. Second, a properly contrasted diagnostic CT sometimes can show the tumor target better than can the planning CT. Third, the diagnostic CT or MR may have been preoperative, with the postoperative planning CT no longer showing the tumor. Fourth, the patient may have undergone cytoreductive chemotherapy so that the postchemotherapy planning CT no longer showed the original tumor volume. In patients in whom the planning CT did not show the tumor volume well an analysis was done to determine how the treatment plan was changed with the addition of a better tumor-defining nonplanning CT or MR. We have found that the use of this additional imaging modality changed the tumor location in the treatment plan at least 1.5 cm for half of the patients, and up to 3.0 cm for ((1)/(4)) of the patients. Conclusions: Multimodality and/or sequential imaging can substantially aid in better tumor

  10. Strategic planning in healthcare organizations.

    Science.gov (United States)

    Rodríguez Perera, Francisco de Paula; Peiró, Manel

    2012-08-01

    Strategic planning is a completely valid and useful tool for guiding all types of organizations, including healthcare organizations. The organizational level at which the strategic planning process is relevant depends on the unit's size, its complexity, and the differentiation of the service provided. A cardiology department, a hemodynamic unit, or an electrophysiology unit can be an appropriate level, as long as their plans align with other plans at higher levels. The leader of each unit is the person responsible for promoting the planning process, a core and essential part of his or her role. The process of strategic planning is programmable, systematic, rational, and holistic and integrates the short, medium, and long term, allowing the healthcare organization to focus on relevant and lasting transformations for the future. Copyright © 2012 Sociedad Española de Cardiología. Published by Elsevier Espana. All rights reserved.

  11. Core designs for new VVER reactors and operational experience of immediate prototypes

    International Nuclear Information System (INIS)

    Vasilchenko, I.; Mokhov, V.; Ryzhov, S.

    2011-01-01

    The paper covers the recent improvements analyzed in order to implement the enhanced core performances. AES-2006 reactor core design is considered from the point of view of its application and improvement in the planned VVER-TOI project and of the possibilities of using the basic engineering solutions for the cores with spectral control. The discussion of several types of mixing grids considered in the paper involves a preliminary assessment of their efficiency and the information on their introduction into pilot operation at the VVER-1000 Units. Special attention is given to the results of the operation of immediate prototypes (TVS-2 and TVS-2M) that corroborate the reliability of the design both with regard for the core geometrical stability and fuel cladding tightness

  12. Historical summary of the Three Mile Island Unit 2 core debris transportation campaign

    Energy Technology Data Exchange (ETDEWEB)

    Schmitt, R.C.; Tyacke, M.J. [EG and G Idaho, Inc., Idaho Falls, ID (United States); Quinn, G.J. [Wastren, Inc., Germantown, MD (United States)

    1993-03-01

    Transport of the damaged core materials from the Unit 2 reactor of the Three Mile Island Nuclear Power Station (TMI-2) to the Idaho National Engineering Laboratory (INEL) for examination and storage presented many technical and institutional challenges, including assessing the ability to transport the damaged core; removing and packaging core debris in ways suitable for transport; developing a transport package that could both meet Federal regulations and interface with the facilities at TMI-2 and the INEL; and developing a transport plan, support logistics, and public communications channels suited to the task. This report is a historical summary of how the US Department of Energy addressed those challenges and transported, received, and stored the TMI-2 core debris at the INEL. Subjects discussed include preparations for transport, loading at TMI-2, institutional issues, transport operations, receipt and storage at the INEL, governmental inquiries/investigations, and lessons learned. Because of public attention focused on the TMI-2 Core Debris Transport Program, the exchange of information between the program and public was extensive. This exchange is a focus for parts of this report to explain why various operations were conducted as they were and why certain technical approaches were employed. And, because of that exchange, the program may have contributed to a better public understanding of such actions and may contribute to planning and execution of similar future actions.

  13. Historical summary of the Three Mile Island Unit 2 core debris transportation campaign

    International Nuclear Information System (INIS)

    Schmitt, R.C.; Tyacke, M.J.; Quinn, G.J.

    1993-03-01

    Transport of the damaged core materials from the Unit 2 reactor of the Three Mile Island Nuclear Power Station (TMI-2) to the Idaho National Engineering Laboratory (INEL) for examination and storage presented many technical and institutional challenges, including assessing the ability to transport the damaged core; removing and packaging core debris in ways suitable for transport; developing a transport package that could both meet Federal regulations and interface with the facilities at TMI-2 and the INEL; and developing a transport plan, support logistics, and public communications channels suited to the task. This report is a historical summary of how the US Department of Energy addressed those challenges and transported, received, and stored the TMI-2 core debris at the INEL. Subjects discussed include preparations for transport, loading at TMI-2, institutional issues, transport operations, receipt and storage at the INEL, governmental inquiries/investigations, and lessons learned. Because of public attention focused on the TMI-2 Core Debris Transport Program, the exchange of information between the program and public was extensive. This exchange is a focus for parts of this report to explain why various operations were conducted as they were and why certain technical approaches were employed. And, because of that exchange, the program may have contributed to a better public understanding of such actions and may contribute to planning and execution of similar future actions

  14. Diagnostic accuracy of organ electrodermal diagnostics | Szopinski ...

    African Journals Online (AJOL)

    Objective. To estimate the diagnostic accuracy as well as the scope of utilisation of a new bio-electronic method of organ diagnostics. Design. Double-blind comparative study of the diagnostic results obtained by means of organ electrodermal diagnostics (OED) and clinical diagnoses, as a criterion standard. Setting.

  15. Transactions of the second technical exchange meeting on fuel- and clad-motion diagnostics for LMFBR safety test facilities

    Energy Technology Data Exchange (ETDEWEB)

    DeVolpi, A. (comp.)

    1976-01-01

    Papers are presented which deal with diagnostic requirements and fuel motion monitoring capabilities of hodoscopes, coded aperture systems, x-ray radiography, and in-core detectors. Separate abstracts and indexing were prepared for each paper. (DG)

  16. Diagnosis demystified: CT as diagnostic tool in endodontics

    Science.gov (United States)

    Shruthi, Nagaraja; Sreenivasa Murthy, B V; Sundaresh, K J; Mallikarjuna, Rachappa

    2013-01-01

    Diagnosis in endodontics is usually based on clinical and radiographical presentations, which are only empirical methods. The role of healing profession is to apply knowledge and skills towards maintaining and restoring the patient's health. Recent advances in imaging technologies have added to correct interpretation and diagnosis. CT is proving to be an effective tool in solving endodontic mysteries through its three-dimensional visualisation. CT imaging offers many diagnostic advantages to produce reconstructed images in selected projection and low-contrast resolution far superior to that of all other X-ray imaging modalities. This case report is an endeavour towards effective treatment planning of cases with root fracture, root resorption using spiral CT as an adjuvant diagnostic tool. PMID:23814212

  17. A Common Definition of the System Operators' Core Activities[Electric Power Transmission System Operator

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-02-15

    In this report a common definition of the system operator's core activities in the Nordic countries is identified and also a list of non-core activities is introduced. As a starting point the common tasks for system responsibility as identified by Nordel has been used for the work. The term TSO (Transmission System Operator) is employed as a common denominator in the report. It is found out that the TSOs carry out common core activities in the roles as a transmission operator, a system operator and a balance settlement responsible. The core activities for the TSO as a transmission network operator are: Maintain the adequate transmission system in the long run and network development plan on the national as well as on the Nordic level using sophisticated analysis and planning methods and tools. Plan the transmission network on the national as well as on the Nordic level utilising new investments, renewal and maintenance of existing network components so that the network is secure to operate and adequate transmission capacity is guaranteed. Aim at timely network expansions using enhanced information exchange between the Nordic TSOs, and on the national level between the TSO and distribution and regional network operators, large consumers and large producers. Secure the technical compatibility with networks across the border and within a country by establishing connection requirements on the national level and ensuring that the national requirements are compatible across the Nordic power system. The core activities for the TSO as a system operator are: Define common technical requirements for the secure system operation using common planning, operation, connection and data exchange procedures. Secure the system operation with the operational planning for the following year by using information exchange between TSOs enabling the TSOs to make the best possible forecast of the global grid situation in order to assess the flows in their network and the available

  18. A Diagnostic Approach to Corrective Reading in the Classroom.

    Science.gov (United States)

    Dietrich, Dorothy M.

    To meet the needs of students reading below their potentials, teachers must learn more about the reading process, become more diagnostic in determining pupils' strengths and weaknesses, and couple their knowledge of reading with an understanding of pupil deficiencies to plan a program to improve the child's ability to read. Diagnosis, though…

  19. Test-Access Planning and Test Scheduling for Embedded Core-Based System Chips

    NARCIS (Netherlands)

    Goel, Sandeep Kumar

    2005-01-01

    Advances in the semiconductor process technology enable the creation of a complete system on one single die, the so-called system chip or SOC. To reduce time-to-market for large SOCs, reuse of pre-designed and pre-veried blocks called cores is employed. Like the design style, testing of SOCs can be

  20. General review of diagnostic systems in EDF PWR units

    International Nuclear Information System (INIS)

    Chevalier, R.; Brasseur, S.; Ricard, B.

    1998-01-01

    Since the beginning of the French nuclear program, Electricite de France (EDF) has looked for ways to improve the availability and safety of its nuclear units. Therefore, monitoring systems on turbogenerators, reactor coolant pumps, primary circuits and core internal structures were designed by the Research and Development Division and implemented with technologies available during the 1970's. However, mainly because of difficulties for data interpretation by plant personnel, EDF subsequently decided to design and develop different tools to help plant operators to process a diagnosis: - a new generation of the Monitoring and Diagnostic System called PSAD, - expert systems for diagnosis on reactor coolant pumps (RCP) 'DIAPO' and turbogenerator units (TG) 'DIVA', - diagnostic guides written for most equipment pending the installation of new monitoring and diagnosis systems. The first version of PSAD, installed in five units, performs on-line monitoring of the turbogenerator shaft line, steam inlet valves, the reactor coolant pumps and the generator stator. The second version not yet implemented, will include Loose Part Detection (LPD) and Core Internal Structure Monitoring (CISM). The level of diagnosis achieved by PSAD depends on the component monitored. The TG and RCP monitoring functions of PSAD compute high level diagnosis descriptors such as natural frequencies and long term trends but do not elaborate a diagnosis automatically. However, a diagnostic assistance window is available on-line, whenever a warning message is displayed, whether for immediate or later action. The window presents a diagnostic approach whose purpose is to find the causes of the symptoms observed. This diagnosis approach is automated in the DIVA and DIAPO expert systems. Numerous potential faults can be identified for both systems thanks to a hierarchy of abnormal situations. The user interactively answers questions when information is needed to progress in the diagnosis. The resulting

  1. Tank 241-BY-109, cores 201 and 203, analytical results for the final report

    International Nuclear Information System (INIS)

    Esch, R.A.

    1997-01-01

    This document is the final laboratory report for tank 241-BY-109 push mode core segments collected between June 6, 1997 and June 17, 1997. The segments were subsampled and analyzed in accordance with the Tank Push Mode Core Sampling and Analysis Plan (Bell, 1997), the Tank Safety Screening Data Quality Objective (Dukelow, et al, 1995). The analytical results are included

  2. Status of the Munich compact core reactor project

    International Nuclear Information System (INIS)

    Boening, K.; Glaeser, W.; Meier, J.; Rau, G.; Roehrmoser, A.; Steichele, E.

    1991-01-01

    A new national, high performance research reactor is being planned in Munich which shall provide an unperturbed thermal neutron flux of about 8.10 14 cm -2 s -1 at only 20 MW power. This object can be achieved with the concept of a small, light water cooled 'compact core' situated in the center of a large heavy water moderator tank. In the first part of this paper an overview is given on the status of the necessary fuel enrichment is discussed. In becomes clear that the potential of the compact core concept can only be developed without compromises when using highly enriched uranium in combination with the new high density fuel. (orig.)

  3. Vinten exposure measurements of the Salem Unit 1 lower core barrel

    International Nuclear Information System (INIS)

    Glennon, P.T.

    1988-01-01

    On November 6, 1987, the lower core barrel of Salem Unit I was removed from the reactor vessel and placed in the refueling pool as part of the unit's ten year inspection program. This paper deals with the supporting actions of the dosimetry group of PSE ampersand G. Prior to the move of the lower core barrel, Westinghouse predicted dose rates at one foot in water as a function of axial distance along the core barrel. This prediction was used in planning the health physics requirements associated with the move. It was agreed that a measurement of the axial dose rates would either lend confidence to the predictions or identify weaknesses in them

  4. Ultrasound-guided core needle biopsy for breast cancer

    International Nuclear Information System (INIS)

    Naqvi, S.Q.H.; Solangi, R.A.; Memon, M.; Solangi, R.A.

    2008-01-01

    To evaluate the efficacy of ultrasound-guided core needle biopsy (US-CNB) as a preoperative diagnostic modality for breast cancer. Females with solid and/or intermediate breast lesions visualized on ultrasonography. Apart from clinical work-up, all the above mentioned patients underwent ultrasound-guided core needle biopsy and excisional biopsy of their breast lesions. The histopathological diagnosis on ultrasound-guided core needle biopsy was then compared with the findings of the excisional biopsy. Out of the total 93 cases, 47(50.5%) had benign lesions on ultrasound; US-CNB showed 24 as fibroadenomata, four with chronic non-specific mastitis, five chronic suppurative mastitis, one tuberculosis, four fat necrosis, two lactational adenoma and seven cases with benign ductal hyperplasia without atypia. Nine (9.7%) cases showed suspicious abnormality on ultrasound; US-CNB revealed five cases with atypical ductal hyperplasia, one ductal carcinoma in situ and three invasive ductal carcinoma. Thirty seven (39.8%) cases were highly suggestive of malignancy on ultrasound; US-CNB showed 34 as invasive ductal carcinoma, two invasive lobular and one medullary carcinoma. Excisional biopsy confirmed the diagnosis of ultrasound-guided core needle biopsy in all cases except four; one case of chronic suppurative mastitis was diagnosed as that of tuberculosis and three cases of atypial ductal hyperplasia as invasive ductal carcinoma. Hence there was no false positive case, but four (4.3%) false negative cases. The sensitivity of the US-CNB was thus 100% and specificity 91.1%. Ultrasound guided core needle biopsy is a satisfactory procedure for the histopathological diagnosis of breast lesions. Any unsatisfactory, suspicious or atypical change on US-CNB should be followed by an open biopsy. (author)

  5. Core Hunter 3: flexible core subset selection.

    Science.gov (United States)

    De Beukelaer, Herman; Davenport, Guy F; Fack, Veerle

    2018-05-31

    Core collections provide genebank curators and plant breeders a way to reduce size of their collections and populations, while minimizing impact on genetic diversity and allele frequency. Many methods have been proposed to generate core collections, often using distance metrics to quantify the similarity of two accessions, based on genetic marker data or phenotypic traits. Core Hunter is a multi-purpose core subset selection tool that uses local search algorithms to generate subsets relying on one or more metrics, including several distance metrics and allelic richness. In version 3 of Core Hunter (CH3) we have incorporated two new, improved methods for summarizing distances to quantify diversity or representativeness of the core collection. A comparison of CH3 and Core Hunter 2 (CH2) showed that these new metrics can be effectively optimized with less complex algorithms, as compared to those used in CH2. CH3 is more effective at maximizing the improved diversity metric than CH2, still ensures a high average and minimum distance, and is faster for large datasets. Using CH3, a simple stochastic hill-climber is able to find highly diverse core collections, and the more advanced parallel tempering algorithm further increases the quality of the core and further reduces variability across independent samples. We also evaluate the ability of CH3 to simultaneously maximize diversity, and either representativeness or allelic richness, and compare the results with those of the GDOpt and SimEli methods. CH3 can sample equally representative cores as GDOpt, which was specifically designed for this purpose, and is able to construct cores that are simultaneously more diverse, and either are more representative or have higher allelic richness, than those obtained by SimEli. In version 3, Core Hunter has been updated to include two new core subset selection metrics that construct cores for representativeness or diversity, with improved performance. It combines and outperforms the

  6. Electron cyclotron-electron Bernstein wave emission diagnostics for the COMPASS tokamak

    Czech Academy of Sciences Publication Activity Database

    Zajac, Jaromír; Preinhaelter, Josef; Urban, Jakub; Žáček, František; Šesták, David; Nanobashvili, S.

    2010-01-01

    Roč. 81, č. 10 (2010), 10D911-10D911 ISSN 0034-6748. [TOPICAL CONFERENCE ON HIGH-TEMPERATURE PLASMA DIAGNOSTICS/18th./. Wildwood, New Jersey, 16.05.2010-20.05.2010] R&D Projects: GA ČR GA202/08/0419 Institutional research plan: CEZ:AV0Z20430508 Keywords : antenna radiation patterns * antennas in plasma * plasma diagnostics * Tokamak Subject RIV: BL - Plasma and Gas Discharge Physics Impact factor: 1.598, year: 2010 http://link.aip.org/link/?RSI/81/10D911

  7. SPECIFICITY OF MANIFACTURING PROCESS VALIDATION FOR DIAGNOSTIC SEROLOGICAL DEVICES

    Directory of Open Access Journals (Sweden)

    O. Yu. Galkin

    2018-02-01

    Full Text Available The aim of this research was to analyze recent scientific literature, as well as national and international legislature on manifacturing process validation of biopharmaceutical production, in particular devices for serological diagnostics. Technology validation in the field of medical devices for serological diagnostics is most influenced by the Technical Regulation for Medical Devices for in vitro Diagnostics State Standards of Ukraine – SSU EN ISO 13485:2015 “Medical devices. Quality management system. Requirements for regulation”, SSU EN ISO 14971:2015 “Medical devices. Instructions for risk management”, Instruction ST-N of the Ministry of Healthcare of Ukraine 42-4.0:2014 “Medications. Suitable industrial practice”, State Pharmacopoeia of Ukraine and Instruction ICH Q9 on risk management. Current recommendations for validations of drugs manufacturing process, including biotechnological manufacturing, can not be directly applied to medical devices for in vitro diagnostics. It was shown that the specifics of application and raw materials require individual validation parameters and process validations for serological diagnostics devices. Critical parameters to consider in validation plans were provided for every typical stage of production of in vitro diagnostics devices on the example of immunoassay kits, such as obtaining protein antigens, including recombinant ones, preparations of mono- and polyclonal antibodies, immunoenzyme conjugates and immunosorbents, chemical reagents etc. The bottlenecks of technologies for in vitro diagnostics devices were analyzed from the bioethical and biosafety points of view.

  8. Quality of Care for Lung Cancer in Taiwan: A Pattern of Care Based on Core Measures in the Taiwan Cancer Database Registry

    Directory of Open Access Journals (Sweden)

    Chun-Ru Chien

    2008-08-01

    Conclusion: It is very likely that significant variation in QOC for lung cancer in Taiwan exists among different types but not locations of hospitals, at least in the diagnostic domain. The introduction of internal benchmarking (TCDB and core measures was associated with some changes, at least in some diagnostic domains, which may lead to improvement in QOC for lung cancer in Taiwan.

  9. [Self-evaluation of core competencies and related factors among baccalaureate nursing students].

    Science.gov (United States)

    Wu, Chen-Ting; Hsieh, Suh-Ing; Hsu, Li-Ling

    2013-02-01

    Evaluations of higher education programs are increasingly centered on the learner and designed to assess learning effectiveness and core competencies. Although the Taiwan Nursing Accreditation Council (TNAC) has established eight core competencies for college nursing departments, little research has been done to identify the most salient contributors to undergraduate nursing students' perceived competency levels. This paper investigates the influence of student demographic factors and learning experience on students' development in terms of a selected sample of core nursing competencies and then identifies factors that significantly predicts such development. This is a cross-sectional descriptive correlational study. We collected data from a sample of freshmen students currently enrolled in a two-year nursing bachelor degree program at a private vocational university in Taipei, Taiwan. Participants self-assessed abilities in designated core nursing competencies using the Competency Inventory of Nursing Students (CINS). A total of 279 of 290 distributed questionnaires were returned and used in data collection, giving this study a valid return rate of 96.2%. Participants earned a mean CINS score of 5.23 (SD = 0.49). Scale dimensions from highest to lowest mean score rank were: ethics, accountability, caring spirit, communication and cooperation, lifelong learning, general clinical nursing skills, critical thinking, and basic biomedical science. Differentiated analysis revealed that nursing students who expressed a strong interest in nursing, had a clear career plan, held aspirations to pursue higher nursing education, designated "major hospital" as their first workplace of choice, designated a post-college department / workplace preference, had participated in campus activities, were outspoken in classroom discussions and debates, made consistent effort to complete homework assignments and prepare for examinations, and performed relatively strong academically earned

  10. Planning Of Drainage Channel Dimension In The Core Zone Of Muara Takus Temple

    Science.gov (United States)

    Saleh, Alfian

    2017-12-01

    Preservation of Cultural Heritage is a dynamic effort to maintain the existence of cultural heritage by protecting, developing, and utilizing the cultural heritage in the contemporary context. To protect the cultural heritage in term of conservation called protection of which the effort to prevent and overcome from damage, it needs to do destruction or obliteration through rescue, security, zoning, maintenance, and restoration of cultural heritage. The most fundamental issue is the hydrological impact of the existence of Hydroelectric Power Koto Panjang located around Muara Takus temple that could threaten the sustainability of the region. In this case, hydroelectric dam frequently causes Kampar Kanan River overflowed thus potentially floods, especially in the rainy season that could eventually submerges Muara Takus area. The total area of the region Muara Takus enshrinement is ± 94.5 hectares that are divided into two main parts. Those are the terrestrial land of ± 56.44 m², and PLTA Koto Panjang lake of ± 38.06 m². Consequently, it is necessary for drainage planning of economical dimension in the core zone of Muara Takus temple. Furthermore, from the data of the maximum rainfall of 101 mm/day obtained a discharge of rainfall of 0.38 m3/second so that this discharge of rainfall can be designed drainage channel dimension to accommodate the discharge of rainfall. From the analysis of dimension designed drainage is the size of 30 cm x 45 cm. this dimension can accommodate the discharge rainfall that is equal to 0.43 m3 / second. Regarding the finding, it can be concluded that the discharge of rainfall that occurred less than discharge calculation of dimensional analysis of drainage channel so that the size of this dimension can accommodate discharge rainfall occurs.

  11. Final results from the development of the diagnostic expert system DESYRE

    International Nuclear Information System (INIS)

    Scherer, K.P.; Eggert, H.; Sheleisiek, K.; Stille, P.; Schoeller, H.

    1997-01-01

    In the Kernforschungszentrum Karlsruhe (KfK), a distributed knowledge based diagnostic system is developed to supervise the primary system including the core of the Kompakte Natriumgekuehlte Kernreaktoranlage (KNK II), a 20 MWe experimental fast reactor. The problem is to detect anomalies and disturbances in the beginning state before fault propagation - early diagnosis - and provide the scram analysis to detect the causality when a system shutdwon occurs. (author). 9 refs, 15 figs

  12. Transjugular liver biopsy : the efficacy of quick-core biopsy needle system

    Energy Technology Data Exchange (ETDEWEB)

    Jung, Gyoo Sik; Ahn, Byung Kwon; Lee, Sang Ouk; Chang, Hee Kyong; Oh, Kyung Seung; Huh, Jin Do; Joh, Young Duk [Kosin Medical College, Pusan (Korea, Republic of)

    1998-02-01

    To evaluate the efficacy of the Quick-Core biopsy needle system in performing transjugular liver biopsy. Between December 1995 and June 1997, eight patients underwent transjugular liver biopsy involving use of the Quick-Core biopsy needle system; the conditions involved were coagulopathy (n=4), thrombocytopenia (n=3), and ascites (n=1). Via the right internal jugular vein, the right hepatic vein was selectively catheterized with a 7-F transjugular guiding catheter, and a14-guage stiffening cannula was then inserted through this catheter; to obtain core tissue, a Quick-Core needle was then advanced into the liver parenchyma through the catheter-cannula combination. Eighteen- and 19-guage needles were used in three and five patients, respectively; specimen size, adequacy of the biopsy specimen and histologic diagnosis were determined, and complications were recorded. Biopsy was successful in all patients. The mean length of the specimen was 1.4 cm (1.0 - 1.8 cm), and all were adequate for pathologic examinations ; specific diagnosis was determined in all patients. There were two malignant neoplasms, two cases of veno-occlusive disease, and one case each of cirrhosis, fulminant hepatitis, Banti syndrome and Budd-Chiari syndrome. One patient complained of neck pain after the procedure, but no serious procedural complications were noted. Our preliminary study shows that the Quick-Core biopsy needle system is safe and provides adequate core tissues with high diagnostic yields. (author). 23 refs., 1 tab., 3 figs.

  13. Transjugular liver biopsy : the efficacy of quick-core biopsy needle system

    International Nuclear Information System (INIS)

    Jung, Gyoo Sik; Ahn, Byung Kwon; Lee, Sang Ouk; Chang, Hee Kyong; Oh, Kyung Seung; Huh, Jin Do; Joh, Young Duk

    1998-01-01

    To evaluate the efficacy of the Quick-Core biopsy needle system in performing transjugular liver biopsy. Between December 1995 and June 1997, eight patients underwent transjugular liver biopsy involving use of the Quick-Core biopsy needle system; the conditions involved were coagulopathy (n=4), thrombocytopenia (n=3), and ascites (n=1). Via the right internal jugular vein, the right hepatic vein was selectively catheterized with a 7-F transjugular guiding catheter, and a14-guage stiffening cannula was then inserted through this catheter; to obtain core tissue, a Quick-Core needle was then advanced into the liver parenchyma through the catheter-cannula combination. Eighteen- and 19-guage needles were used in three and five patients, respectively; specimen size, adequacy of the biopsy specimen and histologic diagnosis were determined, and complications were recorded. Biopsy was successful in all patients. The mean length of the specimen was 1.4 cm (1.0 - 1.8 cm), and all were adequate for pathologic examinations ; specific diagnosis was determined in all patients. There were two malignant neoplasms, two cases of veno-occlusive disease, and one case each of cirrhosis, fulminant hepatitis, Banti syndrome and Budd-Chiari syndrome. One patient complained of neck pain after the procedure, but no serious procedural complications were noted. Our preliminary study shows that the Quick-Core biopsy needle system is safe and provides adequate core tissues with high diagnostic yields. (author). 23 refs., 1 tab., 3 figs

  14. Liquid metal reactor core material HT9

    International Nuclear Information System (INIS)

    Kim, S. H.; Kuk, I. H.; Ryu, W. S. and others

    1998-03-01

    A state-of-the art is surveyed on the liquid metal reactor core materials HT9. The purpose of this report is to give an insight for choosing and developing the materials to be applied to the KAERI prototype liquid metal reactor which is planned for the year of 2010. In-core stability of cladding materials is important to the extension of fuel burnup. Austenitic stainless steel (AISI 316) has been used as core material in the early LMR due to the good mechanical properties at high temperatures, but it has been found to show a poor swelling resistance. So many efforts have been made to solve this problem that HT9 have been developed. HT9 is 12Cr-1MoVW steel. The microstructure of HT9 consisted of tempered martensite with dispersed carbide. HT9 has superior irradiation swelling resistance as other BCC metals, and good sodium compatibility. HT9 has also a good irradiation creep properties below 500 dg C, but irradiation creep properties are degraded above 500 dg C. Researches are currently in progress to modify the HT9 in order to improve the irradiation creep properties above 500 dg C. New design studies for decreasing the core temperature below 500 dg C are needed to use HT9 as a core material. On the contrary, decrease of the thermal efficiency may occur due to lower-down of the operation temperature. (author). 51 refs., 6 tabs., 19 figs

  15. Three principles to define the success of a diagnostic study could be identified

    DEFF Research Database (Denmark)

    Vach, Werner; Gerke, Oke; Høilund-Carlsen, Poul Flemming

    2012-01-01

    of a diagnostic study on a single binary test and investigation of common statistical approaches in relation to these criteria. RESULTS: Three criteria for defining the overall success of a diagnostic study could be identified: a strong criterion, a liberal criterion, and a weak criterion. The strong criterion...... can be implemented by comparing the lower bounds of the confidence intervals for sensitivity and specificity with prespecified target values, as is typically done in many diagnostic studies. The liberal criterion allows a clinically meaningful compensation between sensitivity and specificity and can...... be implemented in different ways. If the liberal criterion is applied instead of the strong criterion, this can lead to a substantial reduction in the sample size required for a diagnostic study. The weak criterion is not very adequate for defining the success of a diagnostic study. CONCLUSION: When planning...

  16. Development of a new virtual diagnostic for V3FIT

    Energy Technology Data Exchange (ETDEWEB)

    Trevisan, G. L., E-mail: gtrevisan@igi.cnr.it; Terranova, D. [Consorzio RFX (CNR, ENEA, INFN, Università di Padova, Acciaierie Venete SpA), corso Stati Uniti 4-35127 Padova (Italy); Cianciosa, M. R.; Hanson, J. D. [Auburn University, Physics Department, Auburn, Alabama 36849 (United States)

    2014-12-15

    The determination of plasma equilibria from diagnostic information is a fundamental issue. V3FIT is a fully three-dimensional reconstruction code capable of solving the inverse problem using both magnetic and kinetic measurements. It uses VMEC as core equilibrium solver and supports both free- and fixed-boundary reconstruction approaches. In fixed-boundary mode VMEC does not use explicit information about currents in external coils, even though it has important effects on the shape of the safety factor profile. Indeed, the edge safety factor influences the reversal position in RFP plasmas, which then determines the position of the m = 0 island chain and the edge transport properties. In order to exploit such information a new virtual diagnostic has been developed, that thanks to Ampère's law relates the external current through the center of the torus to the circulation of the toroidal magnetic field on the outermost flux surface. The reconstructions that exploit the new diagnostic are indeed found to better interpret the experimental data with respect to edge physics.

  17. Recent improvements in on-line core supervision at Loviisa NPP

    International Nuclear Information System (INIS)

    Antila, M.; Kuusisto, J.

    1999-01-01

    On-line core supervision system (RESU) based on monitoring of local fuel limits has been in use at the Loviisa VVER-440 reactors for more than twenty years. Minor modifications were made ten years ago when the computer hardware was upgraded. In April 1998 Loviisa got the licence for 1500 MW power. Power uprating and introduction of new fuel types gave rise to the latest improvements in the core supervision system, which is called RESU-98. In August 1999 the Finnish Safety Authority (STUK) has given approval for RESU-98, which is now in use at the Loviisa NPP. RESU-98 includes essentially the same computer codes, which are used in reload planning. The extensive in-core instrumentation is utilised to adjust the theoretical 3D-power distribution to get a best-estimate results. In this paper a general review of the RESU-98 system is given including instrumentation, methods, core monitoring, predictive functions and validation. Special attention is paid on the recent improvements. (Authors)

  18. Recent improvements in on-line core supervision at Loviisa NPP

    International Nuclear Information System (INIS)

    Antila, M.; Kuusisto, J.

    2000-01-01

    AN on-line core supervision system (RESU) based on monitoring of local fuel limits has been in use at the Loviisa VVER-440 reactors for more than twenty years. Minor modifications were made ten years ago to upgrade the computer hardware. In April 1998 Loviisa obtained a licence for 1500 MW th power. Power up-rating and introduction of new fuel types gave rise to the latest improvements in the core supervision system, which is called RESU-98. In August 1999 the Finnish Safety Authority (STUCK) officially approved RESU-98, which is now in use at the Loviisa NPP. RESU-98 includes essentially the same computer codes, which are used in reload planning. The extensive in-core instrumentation is utilised to adjust the theoretical 3-D power distribution to get a best-estimate result. In this paper a general review of the RESU-98 system is given including instrumentation, methods, core monitoring, predictive functions and validation. Special attention is paid to recent improvements. (author)

  19. TARMS, an on-line boiling water reactor operation management system. [3 D core simulator LOGOS 2

    Energy Technology Data Exchange (ETDEWEB)

    Iwamoto, T.; Sakurai, S.; Uematsu, H.; Tsuiki, M.; Makino, K.

    1984-12-01

    The TARMS (Toshiba Advanced Reactor Management System) software package was developed as an effective on-line, on-site tool for boiling water reactor core operation management. It was designed to support a complete function set to meet the requirement to the current on-line process computers. The functions can be divided into two categories. One is monitoring of the present core power distribution as well as related limiting parameters. The other is aiding site engineers or reactor operators in making the future reactor operating plan. TARMS performs these functions with a three-dimensional BWR core physics simulator LOGOS 2, which is based on modified one-group, coarse-mesh nodal diffusion theory. A method was developed to obtain highly accurate nodal powers by coupling LOGOS 2 calculations with the readings of an in-core neutron flux monitor. A sort of automated machine-learning method also was developed to minimize the errors caused by insufficiency of the physics model adopted in LOGOS 2. In addition to these fundamental calculational methods, a number of core operation planning aid packages were developed and installed in TARMS, which were designed to make the operator's inputs simple and easy.

  20. Business plan of a food truck in Saint Petersburg

    OpenAIRE

    Zavyalova, Ekaterina

    2017-01-01

    The purpose of the thesis was to investigate how to write a proper business plan and then implement gained knowledge in creating a business plan of a food truck in Saint Petersburg. A business plan serves as a guide for an entrepreneur in the process of company establishment and enables to gain funding from potential investors. The primary objective was to study essential components of a business plan. The theoretical framework comprises of core issues on company establishment and desc...

  1. Twelfth meeting of the ITER physics expert group on diagnostics

    International Nuclear Information System (INIS)

    Costley, A.E.; Donne, A.J.H.

    2000-01-01

    The main technical objectives of the meeting were to review the present status of ITER and to determine any required changes in the specifications for plasma measurements; to review the progress and develop plans for meeting the goals of the voluntary R and D tasks approved by the ITER Physics Committee within the Parties; to review and plan the work of the five specialists electronic working groups, and to hear reports of ITER relevant diagnostic developments in the Party Laboratories and assess their possible application to ITER

  2. Axillary lymph node core biopsy for breast cancer metastases — How many needle passes are enough?

    International Nuclear Information System (INIS)

    Macaskill, E.J.; Purdie, C.A.; Jordan, L.B.; Mclean, D.; Whelehan, P.; Brown, D.C.; Evans, A.

    2012-01-01

    Aim: To determine the diagnostic yield of each of three core passes when sampling abnormal lymph nodes in patients presenting with breast cancer. Materials and methods: All patients suspected of having breast cancer had axillary ultrasound as part of initial assessment. Radiologically abnormal nodes (cortical thickness >2.3 mm or round shape) were biopsied with three passes of a 22 mm throw 14 G core biopsy needle and sent for histopathology in separate numbered pots. Data were collected prospectively, and analysis performed on the data of 55 consecutive patients who had positive nodes on at least one core biopsy needle pass. Results: Of 55 patients with a positive node on core biopsy, tumour was noted in all three cores taken in 39 (70.9%). Lymph node metastasis was detected in 45 (81.8%) first core biopsies. With the first two cores taken, positive results were detected in 53 of 55 cases (96.4%). In both cases where tumour was only found on a third core biopsy pass, no lymph node tissue was present in the first two biopsy passes. Conclusion: Two well-directed 14 G core biopsy samples from an abnormal axillary node are adequate for diagnosis of breast cancer metastasis.

  3. Applications of a surveillance and diagnostics methodology using neutron noise from a pressurized-water reactor

    International Nuclear Information System (INIS)

    Wood, R.T.; Miller, L.F.; Perez, R.B.

    1992-01-01

    Two applications of a noise diagnostic methodology were performed with ex-core neutron detector data from a pressurized-water reactor (PWR). A feedback dynamics model of the neutron power spectral denisty was derived from a low-order whole-plant physical model made stochastic with the Langevin technique. From a functional fit to plant data, the response of the dynamic system to changes in important physical parameters was evaluated by a direct sensitivity analysis. In addition, changes in monitored spectra were related to changes in physical parameters, and detection thresholds using common surveillance discriminants were determined. A resonance model was developed from perturbation theory to give the ex-core neutron detector response for small in-core mechanical motions in terms of a pole-strength factor, a resonance asymmetry (or skewness) factor, a vibration damping factor, and a frequency of vibration. The mechanical motion paramters for several resonances were determined by a functional fit of the model to plant data taken at various times during a fuel cycle and were tracked to determined trends that indicated vibrational changes of reactor internals. In addition, the resonance model gave the ability to separate the resonant components of the power spectral density after the parameters had been identified. As a result, the behavior of several vibration peaks was monitored over a fuel cycle. The noise diagnostic methodology illustrated by these applications can be used in monitoring the condition of the reactor system. Early detection of degraded mechanical components or undesirable operating conditions by using such surveillance and diagnostic techniques would enhance plant safety. 15 refs., 6 figs., 1 tab

  4. Los Alamos contribution to target diagnostics on the National Ignition Facility

    Energy Technology Data Exchange (ETDEWEB)

    Mack, J.M.; Baker, D.A.; Caldwell, S.E. [and others

    1994-07-01

    The National Ignition Facility (NIF) will have a large suite of sophisticated target diagnostics. This will allow thoroughly diagnosed experiments to be performed both at the ignition and pre-ignition levels. As part of the national effort Los Alamos National Laboratory will design, construct and implement a number of diagnostics for the NIF. This paper describes Los Alamos contributions to the ``phase I diagnostics.`` Phase I represents the most fundamental and basic measurement systems that will form the core for most work on the NIF. The Los Alamos effort falls into four categories: moderate to hard X-ray (time resolved imaging neutron spectroscopy- primarily with neutron time of flight devices; burn diagnostics utilizing gamma ray measurements; testing measurement concepts on the TRIDENT laser system at Los Alamos. Because of the high blast, debris and radiation environment, the design of high resolution X-ray imaging systems present significant challenges. Systems with close target proximity require special protection and methods for such protection is described. The system design specifications based on expected target performance parameters is also described. Diagnosis of nuclear yield and burn will be crucial to the NIF operation. Nuclear reaction diagnosis utilizing both neutron and gamma ray detection is discussed. The Los Alamos TRIDENT laser system will be used extensively for the development of new measurement concepts and diagnostic instrumentation. Some its potential roles in the development of diagnostics for NIF are given.

  5. Los Alamos contribution to target diagnostics on the National Ignition Facility

    International Nuclear Information System (INIS)

    Mack, J.M.; Baker, D.A.; Caldwell, S.E.

    1994-01-01

    The National Ignition Facility (NIF) will have a large suite of sophisticated target diagnostics. This will allow thoroughly diagnosed experiments to be performed both at the ignition and pre-ignition levels. As part of the national effort Los Alamos National Laboratory will design, construct and implement a number of diagnostics for the NIF. This paper describes Los Alamos contributions to the ''phase I diagnostics.'' Phase I represents the most fundamental and basic measurement systems that will form the core for most work on the NIF. The Los Alamos effort falls into four categories: moderate to hard X-ray (time resolved imaging neutron spectroscopy- primarily with neutron time of flight devices; burn diagnostics utilizing gamma ray measurements; testing measurement concepts on the TRIDENT laser system at Los Alamos. Because of the high blast, debris and radiation environment, the design of high resolution X-ray imaging systems present significant challenges. Systems with close target proximity require special protection and methods for such protection is described. The system design specifications based on expected target performance parameters is also described. Diagnosis of nuclear yield and burn will be crucial to the NIF operation. Nuclear reaction diagnosis utilizing both neutron and gamma ray detection is discussed. The Los Alamos TRIDENT laser system will be used extensively for the development of new measurement concepts and diagnostic instrumentation. Some its potential roles in the development of diagnostics for NIF are given

  6. Divergence-based tests for model diagnostic

    Czech Academy of Sciences Publication Activity Database

    Hobza, Tomáš; Esteban, M. D.; Morales, D.; Marhuenda, Y.

    2008-01-01

    Roč. 78, č. 13 (2008), s. 1702-1710 ISSN 0167-7152 R&D Projects: GA MŠk 1M0572 Grant - others:Instituto Nacional de Estadistica (ES) MTM2006-05693 Institutional research plan: CEZ:AV0Z10750506 Keywords : goodness of fit * devergence statistics * GLM * model checking * bootstrap Subject RIV: BB - Applied Statistics, Operational Research Impact factor: 0.445, year: 2008 http://library.utia.cas.cz/separaty/2008/SI/hobza-divergence-based%20tests%20for%20model%20diagnostic.pdf

  7. Reactor core with rod-shaped fuel cells

    International Nuclear Information System (INIS)

    Dworak, A.

    1977-01-01

    The aim is an optimization of load distribution in the core so that the load decreases in the direction of coolant flow (with gas cooling from above downwards) but so that it remains constant in horizontal layers to the edge of the core. The former produces optimum cooling, because the coolant has to take up decreasing heat output in the direction of flow. The latter simplifies refueling, because replacement of a whole layer having the same burn-up takes place. The upper two layers with the highest output and the shortest dwell time are replaced every 300 days, for example, the third layer is replaced after double this time and 5 more layers after four times this dwell time. After the simultaneous replacement of all layers, the reactor is in the same state as at commissioning. The fuel cells consist of hexagonal graphite blocks about 1.65 metres in height and 0.75 wide, for example. Each block contains about 100 through cooling channels and about 200 fuel channels closed on both sides. A large number of columns each consisting of 8 blocks is arranged in a tight honeycomb pattern and forms the core. Within each of the 8 horizontal layers of blocks, each fuel cell contains the same fuel mixture with predetermined dwell time. The fuel mixture is suited to the dwell time planned for each layer. The various fuel cells are kept at the same output by burnable neutron poisons in special channels provided for this purpose in the fuel cell and/or by absorber rods, or a planned load distribution is maintained. (HP) [de

  8. New plan of strategy and organization. Annual report 1995; Ny strategisk plan og organisasjon. Aarsberetning 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-10-01

    The annual report from EFI (Norwegian Research Institute for Electricity) relates to an new strategic plan and organization of the institute. An example of this is the Research Council of Norway`s new R and D programme EFFEKT, which will be a major locomotive for research up to the year 2000. Topics are: EFI`s new strategic plan and organization; extracts from the Board`s annual report; extract from the accounts; diagnostic testing of circuit-breakers; breakdown and interruption statistics from the grid; power system reliability

  9. Effects of nitrogen seeding on core ion thermal transport in JET ILW L-mode plasmas

    NARCIS (Netherlands)

    Bonanomi, N.; Mantica, P.; Citrin, J.; Giroud, C.; Lerche, E.; Sozzi, C.; Taylor, D.; Tsalas, M.; Van Eester, D.; JET Contributors,

    2018-01-01

    A set of experiments was carried out in JET ILW (Joint European Torus with ITER-Like Wall) L-mode plasmas in order to study the effects of light impurities on core ion thermal transport. N was puffed into some discharges and its profile was measured by active Charge Exchange diagnostics, while ICRH

  10. Noise diagnostics research at the Institute for Electric Power Research

    International Nuclear Information System (INIS)

    Voeroess, L.

    1983-01-01

    The main goal of recent research is the designing of a diagnostic system for the Paks nuclear power plant. It includes the designing of measuring cascades for measuring mechanical vibrations caused by flow and pressure fluctuations in the primary coolant circuit, the arrangement of measuring cascades for measuring turbine bearing vibrations in the secondary coolant circuit, and the development, manufacturing and commissioning of a central data acquisition and processing unit for the whole diagnostic system. Simultaneously computer models are developed for improving the interpretation. Moreover, it is planned to develop methods for estimating residual lifetime and the status of plant components. (author)

  11. Development and psychometric evaluation of the Core Nurse Resource Scale.

    Science.gov (United States)

    Simpson, Michelle R

    2010-11-01

    To examine the factor structure, internal consistency reliability and concurrent-related validity of the Core Nurse Resource Scale. A cross-sectional survey study design was used to obtain a sample of 149 nurses and nursing staff [Registered Nurse (RNs), Licensed Practical Nurse (LPNs) and Certified Nursing Assistant (CNAs)] working in long-term care facilities. Exploratory factor analysis, Cronbach's alpha and bivariate correlations were used to evaluate validity and reliability. Exploratory factor analysis yielded a scale with 18 items on three factors, accounting for 52% of the variance in scores. Internal consistency reliability for the composite and Core Nurse Resource Scale factors ranged from 0.79 to 0.91. The Core Nurse Resource Scale composite scale and subscales correlated positively with a measure of work engagement (r=0.247-0.572). The initial psychometric evaluation of the Core Nurse Resource Scale demonstrates it is a sound measure. Further validity and reliability assessment will need to be explored and assessed among nurses and other nursing staff working in other practice settings. The intent of the Core Nurse Resource Scale is to evaluate the presence of physical, psychological and social resources of the nursing work environment, to identify workplaces at risk for disengaged (low work engagement) nursing staff and to provide useful diagnostic information to healthcare administrators interested in interventions to improve the nursing work environment. © 2010 The Author. Journal compilation © 2010 Blackwell Publishing Ltd.

  12. Plan Nacional de Desarrollo y Seguridad 1971-1975 (National Plan for Development and Security, 1971-1975).

    Science.gov (United States)

    Boletin del Centro Nacional de Documentacion e Informacion Educativa, 1971

    1971-01-01

    This article discusses the education provisions established in the Argentine Plan for Development and Security (1971-1975). The statements on educational development call for a diagnostic study of the current cultural and educational situation, the establishment of objectives and strategies, goals for each level of education, steps for the…

  13. Equipment concept design and development plans for microgravity science and applications research on space station: Combustion tunnel, laser diagnostic system, advanced modular furnace, integrated electronics laboratory

    Science.gov (United States)

    Uhran, M. L.; Youngblood, W. W.; Georgekutty, T.; Fiske, M. R.; Wear, W. O.

    1986-01-01

    Taking advantage of the microgravity environment of space NASA has initiated the preliminary design of a permanently manned space station that will support technological advances in process science and stimulate the development of new and improved materials having applications across the commercial spectrum. Previous studies have been performed to define from the researcher's perspective, the requirements for laboratory equipment to accommodate microgravity experiments on the space station. Functional requirements for the identified experimental apparatus and support equipment were determined. From these hardware requirements, several items were selected for concept designs and subsequent formulation of development plans. This report documents the concept designs and development plans for two items of experiment apparatus - the Combustion Tunnel and the Advanced Modular Furnace, and two items of support equipment the Laser Diagnostic System and the Integrated Electronics Laboratory. For each concept design, key technology developments were identified that are required to enable or enhance the development of the respective hardware.

  14. Development of procedures to ensure quality and integrity in Tandem Mirror Experiment-Upgrade (TMX-U) diagnostics systems

    International Nuclear Information System (INIS)

    Coutts, G.W.; Coon, M.L.; Hinz, A.F.; Hornady, R.S.; Lang, D.D.; Lund, N.P.

    1983-01-01

    The diagnostic systems for Tandem Mirror Experiment-Upgrade (TMX-U) have grown from eleven initial systems to more than twenty systems. During operation, diagnostic system modifications are sometimes required to complete experimental objectives. Also, during operations new diagnostic systems are being developed and implemented. To ensure and maintain the quality and integrity of the data signals, a set of plans and systematic actions are being developed. This paper reviews the procedures set in place to maintain the integrity of existing data systems and ensure the performance objectives of new diagnostics being added

  15. Analysis Of Core Management For The Transition Cores Of RSG-GAS Reactor To Full-Silicide Core

    International Nuclear Information System (INIS)

    Malem Sembiring, Tagor; Suparlina, Lily; Tukiran

    2001-01-01

    The core conversion of RSG-GAS reactor from oxide to silicide core with meat density of 2.96 g U/cc is still doing. At the end of 2000, the reactor has been operated for 3 transition cores which is the mixed core of oxide-silicide. Based on previous work, the calculated core parameter for the cores were obtained and it is needed 10 transition cores to achieve a full-silicide core. The objective of this work is to acquire the effect of the increment of the number of silicide fuel on the core parameters such as excess reactivity and shutdown margin. The measurement of the core parameters was carried out using the method of compensation of couple control rods. The experiment shows that the excess reactivity trends lower with the increment of the number of silicide fuel in the core. However, the shutdown margin is not change with the increment of the number of silicide fuel. Therefore, the transition cores can be operated safety to a full-silicide core

  16. TH-E-201-01: Diagnostic Radiology Residents Physics Curriculum and Updates

    Energy Technology Data Exchange (ETDEWEB)

    Sensakovic, W. [Florida Hospital (United States)

    2016-06-15

    The ABR Core Examination stresses integrating physics into real-world clinical practice and, accordingly, has shifted its focus from passive recall of facts to active application of physics principles. Physics education of radiology residents poses a challenge. The traditional method of didactic lectures alone is insufficient, yet it is difficult to incorporate physics teaching consistently into clinical rotations due to time constraints. Faced with this challenge, diagnostic medical physicists who teach radiology residents, have been thinking about how to adapt their teaching to the new paradigm, what to teach and meet expectation of the radiology resident and the radiology residency program. The proposed lecture attempts to discuss above questions. Newly developed diagnostic radiology residents physics curriculum by the AAPM Imaging Physics Curricula Subcommittee will be reviewed. Initial experience on hands-on physics teaching will be discussed. Radiology resident who will have taken the BAR Core Examination will share the expectation of physics teaching from a resident perspective. The lecture will help develop robust educational approaches to prepare radiology residents for safer and more effective lifelong practice. Learning Objectives: Learn updated physics requirements for radiology residents Pursue effective approaches to teach physics to radiology residents Learn expectation of physics teaching from resident perspective J. Zhang, This topic is partially supported by RSNA Education Scholar Grant.

  17. TH-E-201-01: Diagnostic Radiology Residents Physics Curriculum and Updates

    International Nuclear Information System (INIS)

    Sensakovic, W.

    2016-01-01

    The ABR Core Examination stresses integrating physics into real-world clinical practice and, accordingly, has shifted its focus from passive recall of facts to active application of physics principles. Physics education of radiology residents poses a challenge. The traditional method of didactic lectures alone is insufficient, yet it is difficult to incorporate physics teaching consistently into clinical rotations due to time constraints. Faced with this challenge, diagnostic medical physicists who teach radiology residents, have been thinking about how to adapt their teaching to the new paradigm, what to teach and meet expectation of the radiology resident and the radiology residency program. The proposed lecture attempts to discuss above questions. Newly developed diagnostic radiology residents physics curriculum by the AAPM Imaging Physics Curricula Subcommittee will be reviewed. Initial experience on hands-on physics teaching will be discussed. Radiology resident who will have taken the BAR Core Examination will share the expectation of physics teaching from a resident perspective. The lecture will help develop robust educational approaches to prepare radiology residents for safer and more effective lifelong practice. Learning Objectives: Learn updated physics requirements for radiology residents Pursue effective approaches to teach physics to radiology residents Learn expectation of physics teaching from resident perspective J. Zhang, This topic is partially supported by RSNA Education Scholar Grant

  18. CAD-Based Shielding Analysis for ITER Port Diagnostics

    Directory of Open Access Journals (Sweden)

    Serikov Arkady

    2017-01-01

    Full Text Available Radiation shielding analysis conducted in support of design development of the contemporary diagnostic systems integrated inside the ITER ports is relied on the use of CAD models. This paper presents the CAD-based MCNP Monte Carlo radiation transport and activation analyses for the Diagnostic Upper and Equatorial Port Plugs (UPP #3 and EPP #8, #17. The creation process of the complicated 3D MCNP models of the diagnostics systems was substantially accelerated by application of the CAD-to-MCNP converter programs MCAM and McCad. High performance computing resources of the Helios supercomputer allowed to speed-up the MCNP parallel transport calculations with the MPI/OpenMP interface. The found shielding solutions could be universal, reducing ports R&D costs. The shield block behind the Tritium and Deposit Monitor (TDM optical box was added to study its influence on Shut-Down Dose Rate (SDDR in Port Interspace (PI of EPP#17. Influence of neutron streaming along the Lost Alpha Monitor (LAM on the neutron energy spectra calculated in the Tangential Neutron Spectrometer (TNS of EPP#8. For the UPP#3 with Charge eXchange Recombination Spectroscopy (CXRS-core, an excessive neutron streaming along the CXRS shutter, which should be prevented in further design iteration.

  19. CAD-Based Shielding Analysis for ITER Port Diagnostics

    Science.gov (United States)

    Serikov, Arkady; Fischer, Ulrich; Anthoine, David; Bertalot, Luciano; De Bock, Maartin; O'Connor, Richard; Juarez, Rafael; Krasilnikov, Vitaly

    2017-09-01

    Radiation shielding analysis conducted in support of design development of the contemporary diagnostic systems integrated inside the ITER ports is relied on the use of CAD models. This paper presents the CAD-based MCNP Monte Carlo radiation transport and activation analyses for the Diagnostic Upper and Equatorial Port Plugs (UPP #3 and EPP #8, #17). The creation process of the complicated 3D MCNP models of the diagnostics systems was substantially accelerated by application of the CAD-to-MCNP converter programs MCAM and McCad. High performance computing resources of the Helios supercomputer allowed to speed-up the MCNP parallel transport calculations with the MPI/OpenMP interface. The found shielding solutions could be universal, reducing ports R&D costs. The shield block behind the Tritium and Deposit Monitor (TDM) optical box was added to study its influence on Shut-Down Dose Rate (SDDR) in Port Interspace (PI) of EPP#17. Influence of neutron streaming along the Lost Alpha Monitor (LAM) on the neutron energy spectra calculated in the Tangential Neutron Spectrometer (TNS) of EPP#8. For the UPP#3 with Charge eXchange Recombination Spectroscopy (CXRS-core), an excessive neutron streaming along the CXRS shutter, which should be prevented in further design iteration.

  20. Core-to-core uniformity improvement in multi-core fiber Bragg gratings

    Science.gov (United States)

    Lindley, Emma; Min, Seong-Sik; Leon-Saval, Sergio; Cvetojevic, Nick; Jovanovic, Nemanja; Bland-Hawthorn, Joss; Lawrence, Jon; Gris-Sanchez, Itandehui; Birks, Tim; Haynes, Roger; Haynes, Dionne

    2014-07-01

    Multi-core fiber Bragg gratings (MCFBGs) will be a valuable tool not only in communications but also various astronomical, sensing and industry applications. In this paper we address some of the technical challenges of fabricating effective multi-core gratings by simulating improvements to the writing method. These methods allow a system designed for inscribing single-core fibers to cope with MCFBG fabrication with only minor, passive changes to the writing process. Using a capillary tube that was polished on one side, the field entering the fiber was flattened which improved the coverage and uniformity of all cores.

  1. The Diagnostics of the kappa-Distributions from EUV Spectra

    Czech Academy of Sciences Publication Activity Database

    Dzifčáková, Elena; Kulinová, Alena

    2010-01-01

    Roč. 263, 1-2 (2010), s. 25-41 ISSN 0038-0938 R&D Projects: GA ČR GA205/09/1705 Grant - others:VEGA(SK) 1/0069/08 Institutional research plan: CEZ:AV0Z10030501 Keywords : EUV spectra * non- thermal distributions * plasma diagnostics Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics Impact factor: 3.386, year: 2010

  2. Comparison of a newly developed automated and quantitative hepatitis C virus (HCV) core antigen test with the HCV RNA assay for clinical usefulness in confirming anti-HCV results.

    Science.gov (United States)

    Kesli, Recep; Polat, Hakki; Terzi, Yuksel; Kurtoglu, Muhammet Guzel; Uyar, Yavuz

    2011-12-01

    Hepatitis C virus (HCV) is a global health care problem. Diagnosis of HCV infection is mainly based on the detection of anti-HCV antibodies as a screening test with serum samples. Recombinant immunoblot assays are used as supplemental tests and for the final detection and quantification of HCV RNA in confirmatory tests. In this study, we aimed to compare the HCV core antigen test with the HCV RNA assay for confirming anti-HCV results to determine whether the HCV core antigen test may be used as an alternative confirmatory test to the HCV RNA test and to assess the diagnostic values of the total HCV core antigen test by determining the diagnostic specificity and sensitivity rates compared with the HCV RNA test. Sera from a total of 212 treatment-naive patients were analyzed for anti-HCV and HCV core antigen both with the Abbott Architect test and with the molecular HCV RNA assay consisting of a reverse transcription-PCR method as a confirmatory test. The diagnostic sensitivity, specificity, and positive and negative predictive values of the HCV core antigen assay compared to the HCV RNA test were 96.3%, 100%, 100%, and 89.7%, respectively. The levels of HCV core antigen showed a good correlation with those from the HCV RNA quantification (r = 0.907). In conclusion, the Architect HCV antigen assay is highly specific, sensitive, reliable, easy to perform, reproducible, cost-effective, and applicable as a screening, supplemental, and preconfirmatory test for anti-HCV assays used in laboratory procedures for the diagnosis of hepatitis C virus infection.

  3. A motional Stark effect diagnostic analysis routine for improved resolution of iota in the core of the large helical device.

    Science.gov (United States)

    Dobbins, T J; Ida, K; Suzuki, C; Yoshinuma, M; Kobayashi, T; Suzuki, Y; Yoshida, M

    2017-09-01

    A new Motional Stark Effect (MSE) analysis routine has been developed for improved spatial resolution in the core of the Large Helical Device (LHD). The routine was developed to reduce the dependency of the analysis on the Pfirsch-Schlüter (PS) current in the core. The technique used the change in the polarization angle as a function of flux in order to find the value of diota/dflux at each measurement location. By integrating inwards from the edge, the iota profile can be recovered from this method. This reduces the results' dependency on the PS current because the effect of the PS current on the MSE measurement is almost constant as a function of flux in the core; therefore, the uncertainty in the PS current has a minimal effect on the calculation of the iota profile. In addition, the VMEC database was remapped from flux into r/a space by interpolating in mode space in order to improve the database core resolution. These changes resulted in a much smoother iota profile, conforming more to the physics expectations of standard discharge scenarios in the core of the LHD.

  4. Diagnostics

    DEFF Research Database (Denmark)

    Donné, A.J.H.; Costley, A.E.; Barnsley, R.

    2007-01-01

    of the measurements—time and spatial resolutions, etc—will in some cases be more stringent. Many of the measurements will be used in the real time control of the plasma driving a requirement for very high reliability in the systems (diagnostics) that provide the measurements. The implementation of diagnostic systems...... on ITER is a substantial challenge. Because of the harsh environment (high levels of neutron and gamma fluxes, neutron heating, particle bombardment) diagnostic system selection and design has to cope with a range of phenomena not previously encountered in diagnostic design. Extensive design and R......&D is needed to prepare the systems. In some cases the environmental difficulties are so severe that new diagnostic techniques are required. The starting point in the development of diagnostics for ITER is to define the measurement requirements and develop their justification. It is necessary to include all...

  5. Design and engineering of optical diagnostics for COMPASS

    Czech Academy of Sciences Publication Activity Database

    Šesták, David; Weinzettl, Vladimír; Bílková, Petra; Böhm, Petr; Aftanas, Milan; Naydenkova, Diana; Stöckel, Jan; Ďuran, Ivan; Walsh, M.J.

    2009-01-01

    Roč. 84, 7-11 (2009), s. 1755-1758 ISSN 0920-3796. [Symposium on Fusion Technology(SOFT-25) /25th./. Rostock, 15.09.2008-19.09.2008] R&D Projects: GA ČR GD202/08/H057 Institutional research plan: CEZ:AV0Z20430508 Keywords : COMPASS * tokamak * optical diagnostic * Thomson scattering Subject RIV: BL - Plasma and Gas Discharge Physics Impact factor: 1.122, year: 2009

  6. Image microarrays derived from tissue microarrays (IMA-TMA: New resource for computer-aided diagnostic algorithm development

    Directory of Open Access Journals (Sweden)

    Jennifer A Hipp

    2012-01-01

    Full Text Available Background: Conventional tissue microarrays (TMAs consist of cores of tissue inserted into a recipient paraffin block such that a tissue section on a single glass slide can contain numerous patient samples in a spatially structured pattern. Scanning TMAs into digital slides for subsequent analysis by computer-aided diagnostic (CAD algorithms all offers the possibility of evaluating candidate algorithms against a near-complete repertoire of variable disease morphologies. This parallel interrogation approach simplifies the evaluation, validation, and comparison of such candidate algorithms. A recently developed digital tool, digital core (dCORE, and image microarray maker (iMAM enables the capture of uniformly sized and resolution-matched images, with these representing key morphologic features and fields of view, aggregated into a single monolithic digital image file in an array format, which we define as an image microarray (IMA. We further define the TMA-IMA construct as IMA-based images derived from whole slide images of TMAs themselves. Methods: Here we describe the first combined use of the previously described dCORE and iMAM tools, toward the goal of generating a higher-order image construct, with multiple TMA cores from multiple distinct conventional TMAs assembled as a single digital image montage. This image construct served as the basis of the carrying out of a massively parallel image analysis exercise, based on the use of the previously described spatially invariant vector quantization (SIVQ algorithm. Results: Multicase, multifield TMA-IMAs of follicular lymphoma and follicular hyperplasia were separately rendered, using the aforementioned tools. Each of these two IMAs contained a distinct spectrum of morphologic heterogeneity with respect to both tingible body macrophage (TBM appearance and apoptotic body morphology. SIVQ-based pattern matching, with ring vectors selected to screen for either tingible body macrophages or apoptotic

  7. Disturbances of Embodiment as Core Phenomena of Depression in Clinical Practice.

    Science.gov (United States)

    Doerr-Zegers, Otto; Irarrázaval, Leonor; Mundt, Adrian; Palette, Virginie

    2017-01-01

    This paper proposes a phenomenological approach to the diagnosis of depression, with the aim of overcoming the broadness and nonspecificity of the concept of major depressive disorder (MDD) in current systems of diagnostic classification of mental disorders. Firstly, we outline the methodological limitations of the current classification systems for the diagnosis of MDD. Secondly, we offer a conceptual differentiation between a "symptomatological" versus a "phenomenological" diagnosis of depression. Thirdly, we propose characteristic "disturbances of embodiment" as the fundamental phenomena of "core depression", which manifest themselves in 3 dimensions: embodied self, embodied intentionality, and embodied time. A more useful diagnosis of depression may be achieved by describing the phenomena that constitute a core depression, in order to avoid the overdiagnosis of MDD and its negative consequences in clinical practice. © 2017 S. Karger AG, Basel.

  8. BUSINESS PLAN BLUEPRINT OF A CAFE IN RUSSIA

    OpenAIRE

    Geraskin, Dmitry

    2010-01-01

    This thesis provides an insight into business plan core chapters from the viewpoint of a starting company in North-Western Russia. The aim of the thesis was to comprehend the main steps on the way to the successful business plan such as the marketing plan, risk management issues, human resource management features and to facet the business idea itself with the help of the project commissioner. Catering business, marketing, risk management and other special literature was used along with i...

  9. OEDGE modeling for the planned tungsten ring experiment on DIII-D

    Directory of Open Access Journals (Sweden)

    J.D. Elder

    2017-08-01

    Full Text Available The OEDGE code is used to model tungsten erosion and transport for experiments with toroidal rings of high-Z metal tiles in the DIII-D tokamak. Such modeling is needed for both experimental and diagnostic design to have estimates of the expected core and edge tungsten density and to understand the various factors contributing to the uncertainties in these calculations. OEDGE simulations are performed using the planned experimental magnetic geometries and plasma conditions typical of both L-mode and inter-ELM H-mode discharges in DIII-D. OEDGE plasma reconstruction based on specific representative discharges for similar geometries is used to determine the plasma conditions applied to tungsten plasma impurity simulations. A new model for tungsten erosion in OEDGE was developed which imports charge-state resolved carbon impurity fluxes and impact energies from a separate OEDGE run which models the carbon production, transport and deposition for the same plasma conditions as the tungsten simulations. These values are then used to calculate the gross tungsten physical sputtering due to carbon plasma impurities which is then added to any sputtering by deuterium ions; tungsten self-sputtering is also included. The code results are found to be dependent on the following factors: divertor geometry and closure, the choice of cross-field anomalous transport coefficients, divertor plasma conditions (affecting both tungsten source strength and transport, the choice of tungsten atomic physics data used in the model (in particular ionization rate for W-atoms, and the model of the carbon flux and energy used for calculating the tungsten source due to sputtering. Core tungsten density is found to be of order 1015m−3 (excluding effects of any core transport barrier and with significant variability depending on the other factors mentioned with density decaying into the scrape off layer. For the typical core density in the plasma conditions examined of 2 to 4

  10. The HTA core model: a novel method for producing and reporting health technology assessments

    DEFF Research Database (Denmark)

    Lampe, Kristian; Mäkelä, Marjukka; Garrido, Marcial Velasco

    2009-01-01

    OBJECTIVES: The aim of this study was to develop and test a generic framework to enable international collaboration for producing and sharing results of health technology assessments (HTAs). METHODS: Ten international teams constructed the HTA Core Model, dividing information contained...... for diagnostic technologies. Two Core HTAs were produced in parallel with developing the model, providing the first real-life testing of the Model and input for further development. The results of formal validation and public feedback were primarily positive. Development needs were also identified and considered....... An online Handbook is available. CONCLUSIONS: The HTA Core Model is a novel approach to HTA. It enables effective international production and sharing of HTA results in a structured format. The face validity of the Model was confirmed during the project, but further testing and refining are needed to ensure...

  11. Coupling between core and cladding modes in a helical core fiber with large core offset

    International Nuclear Information System (INIS)

    Napiorkowski, Maciej; Urbanczyk, Waclaw

    2016-01-01

    We analyzed the effect of resonant coupling between core and cladding modes in a helical core fiber with large core offset using the fully vectorial method based on the transformation optics formalism. Our study revealed that the resonant couplings to lower order cladding modes predicted by perturbative methods and observed experimentally in fibers with small core offsets are in fact prohibited for larger core offsets. This effect is related to the lack of phase matching caused by elongation of the optical path of the fundamental modes in the helical core. Moreover, strong couplings to the cladding modes of the azimuthal modal number much higher than predicted by perturbative methods may be observed for large core offsets, as the core offset introduces higher order angular harmonics in the field distribution of the fundamental modes. Finally, in contrast to previous studies, we demonstrate the existence of spectrally broad polarization sensitive couplings to the cladding modes suggesting that helical core fibers with large core offsets may be used as broadband circular polarizers. (paper)

  12. Research reactor core conversion programmes, Department of Research and Isotopes, International Atomic Energy Agency

    International Nuclear Information System (INIS)

    Muranaka, R.G.

    1985-01-01

    In order to put the problem of core conversion into perspective, statistical information on research reactors on a global scale is presented (from IAEA Research reactor Data Base). This paper describes the research reactor core conversion program of the Department of Research and Isotopes. Technical committee Meetings were held on the subject of research reactor core conversion since 1978, and results of these meetings are published in TECDOC-233, TECDOC-324, TECDOC-304. Additional publications are being prepared, several missions of experts have visited countries to discuss and help to plan core conversion programs; training courses and seminars were organised; IAEA has supported attendance of participants from developing countries to RERTR Meetings

  13. Refurbishment, core conversion and safety analysis of Apsara reactor

    Energy Technology Data Exchange (ETDEWEB)

    Raina, V.K.; Sasidharan, K.; Sengupta, S. [Bhabha Atomic Research Centre, Mumbai (India)]. E-mail: nram@@apsara.barc.ernet.in

    1998-07-01

    Apsara, a 1 MWt pool type reactor using HEU fuel has been in operation at the Bhabha Atomic Research Centre, Trombay since 1956. In view of the long service period seen by the reactor it is now planned to carry out extensive refurbishment of the reactor with a view to extend its useful life. It is also proposed to modify the design of the reactor wherein the core will be surrounded by a heavy water reflector tank to obtain a good thermal neutron flux over a large radial distance from the core. Beam holes and the majority of the irradiation facilities will be located inside the reflector tank. The coolant flow direction through the core will be changed from the existing upward flow to downward flow. A delay tank, located inside the pool, is provided to facilitate decay of short lived radioactivity in the coolant outlet from the core in order to bring down radiation field in the operating areas. Analysis of various anticipated operational occurrences and accident conditions like loss of normal power, core coolant flow bypass, fuel channel blockage and degradation of primary coolant pressure boundary have been performed for the proposed design. Details of the proposed design modifications and the safety analyses are given in the paper. (author)

  14. Core schemas and suicidality in a chronically traumatized population.

    Science.gov (United States)

    Dutra, Lissa; Callahan, Kelley; Forman, Evan; Mendelsohn, Michaela; Herman, Judith

    2008-01-01

    The Young Schema Questionnaire (YSQ) has been demonstrated to tap into core beliefs, or maladaptive schemas, of clinical populations. This study used the YSQ to investigate maladaptive schemas of 137 chronically traumatized patients seeking outpatient psychiatric treatment and to assess whether specific schemas might be associated with suicide risk in this population. Participants completed a modified version of the YSQ-S (short form), post-traumatic diagnostic scale, dissociative experiences scale and self-harm and risk behaviors questionnaire-revised at treatment intake. Significant correlations were found between most YSQ scales and the post-traumatic diagnostic scale, and between all YSQ scales and the dissociative experiences scale. Suicide risk variables were most highly correlated with the social isolation/alienation, defectiveness/shame and failure YSQ scales, suggesting that these schemas may mark individuals at particularly high risk for suicidal ideation and suicide attempts. These results offer important implications for the assessment and treatment of high-risk traumatized patients.

  15. Qualification testing program plan for SIMMER. A computer code for LMFBR disrupted core analysis

    International Nuclear Information System (INIS)

    Basdekas, D.L.; Silberberg, M.; Curtis, R.T.; Kelber, C.N.

    1978-07-01

    The objective of SIMMER qualification testing program is to assure that the mathematical models and input parameters are derived from experimental data, which, on the basis of criteria still to be established, are representative of the phenomena and processes governing the progression of a CDA in an LMFBR. At the present time, the work to meet this objective can be classified into three general task areas as they relate to the use of SIMMER in CDA analysis: (1) The whole-core energetic disassembly accident, or the ''vessel problem'': The objective here is to predict the partition of the total energy release, by a postulated severe power excursion, between the primary containment and the energy absorbed through nondestructive dissipative processes. (2) Single subassembly accident: The objective here is to determine the pertinent phenomena and to develop the capability to assess the significance and likelihood that such accidents might propagate to involvement of larger fraction of the core. (3) The whole-core transition phase accident: The objective here is to advance the understanding of the phenomena and processes involved, so that reliable predictions can be made of the possible consequences of a CDA and the potential for further nuclear excursions through recriticality

  16. Evaluation of In-Core Fuel Management for the Transition Cores of RSG-GAS Reactor to Full-Silicide Core

    International Nuclear Information System (INIS)

    S, Tukiran; MS, Tagor; P, Surian

    2003-01-01

    The core conversion of RSG-GAS reactor from oxide to silicide core with meat density of 2.96 gU/cc has been done. The core-of RSG-GAS reactor has been operated full core of silicide fuels which is started with the mixed core of oxide-silicide start from core 36. Based on previous work, the calculated core parameter for the cores were obtained and it is needed 9 transition cores (core 36 - 44) to achieve a full-silicide core (core 45). The objective of this work is to acquire the effect of the increment of the number of silicide fuel on the core parameters. Conversion core was achieved by transition cores mixed oxide-silicide fuels. Each transition core is calculated and measured core parameter such as, excess reactivity and shutdown margin. Calculation done by Batan-EQUIL-2D code and measurement of the core parameters was carried out using the method of compensation of couple control rods. The results of calculation and experiment shows that the excess reactivity trends lower with the increment of the number of silicide fuel in the core. However, the shutdown margin is not change with the increment of the number of silicide fuel. Therefore, the transition cores can be operated safely to a full-silicide core

  17. Percutaneous CT-Guided Core Needle Biopsy Versus Fine Needle Aspiration in Diagnosing Pneumonia and Mimics of Pneumonia

    International Nuclear Information System (INIS)

    Thanos, Loukas; Galani, Panagiota; Mylona, Sophia; Pomoni, Maria; Mpatakis, Nikolaos

    2004-01-01

    The purpose of this study was to determine the diagnostic value of percutaneous core needle biopsy (CNB) relative to fine needle aspiration (FNA) in patients with pneumonia and pneumonia mimics. In this prospective study we present our experience with 48 thoracic FNAs and CNBs carried out on 48 patients with pneumonia and pneumonia mimics. Samples were obtained from all patients using both CNB (with an automated 18-G core biopsy needle and a gun) and FNA (with a 22-G needle). A specific diagnosis was made in 10/48 cases (20.83%) by FNA and in 42/48 (87.5%) by CNB. The main complications encountered were pneumothorax (n = 4) and hemoptysis (n = 2), yielding a total complication rate of 12.5%. We concluded that CNB using an automated biopsy gun results in a higher diagnostic accuracy for pneumonia and pneumonia mimic biopsies than FNA. Complications should be considered and proper patient observation should follow the procedure

  18. New finite element-based modeling of reactor core support plate failure

    Energy Technology Data Exchange (ETDEWEB)

    Pandazis, Peter; Lovasz, Liviusz [Gesellschaft fuer Anlagen- und Reaktorsicherheit gGmbH, Garching (Germany). Forschungszentrum; Babcsany, Boglarka [Budapest Univ. of Technology and Economics, Budapest (Hungary). Inst. of Nuclear Techniques; Hajas, Tamas

    2017-12-15

    ATHLET-CD is the severe accident module of the code system AC{sup 2} that is designed to simulate the core degradation phenomena including fission product release and transport in the reactor circuit, as well as the late phase processes in the lower plenum. In case of a severe accident degradation of the reactor core occurs, the fuel assemblies start to melt. The evolution of such processes is usually accompanied with the failure of the core support plate and relocation of the molten core to the lower plenum. Currently, the criterion for the failure of the support plate applied by ATHLET-CD is a user-defined signal which can be a specific time or process variable like mass, temperature, etc. A new method, based on FEM approach, was developed that could lead in the future to a more realistic criterion for the failure of the core support plate. This paper presents the basic idea and theory of this new method as well as preliminary verification calculations and an outlook on the planned future development.

  19. Microscopic findings in EUS-guided fine needle (SharkCore) biopsies with type 1 and type 2 autoimmune pancreatitis

    DEFF Research Database (Denmark)

    Detlefsen, Sönke; Joergensen, Maiken Thyregod; Mortensen, Michael Bau

    2017-01-01

    The International Consensus Diagnostic Criteria (ICDC) for the diagnosis of autoimmune pancreatitis (AIP) include the histological criterion that is based on either pancreatic core needle biopsies (CNBs) or surgical specimens. However, CNBs are difficult to obtain by endoscopic ultrasound (EUS......). EUS fine-needle aspiration (EUS-FNA) cytology is usually not sufficient for the diagnosis of AIP, but may sometimes contain tissue microfragments. Another approach is EUS-guided histological fine-needle biopsy (EUS-FNB), using needles such as the SharkCore or ProCore needle. Published data regarding...... EUS-guided SharkCore FNB for the diagnosis of AIP are lacking. We aimed to describe our histological findings in one type 1 and two type 2 AIP patients who underwent EUS SharkCore FNB. The EUS-FNBs of two patients fulfilled the histological level 2 ICDC for type 1 AIP or type 2 AIP. The EUS-FNB of one...

  20. A Review of Inflammatory Processes of the Breast with a Focus on Diagnosis in Core Biopsy Samples

    Directory of Open Access Journals (Sweden)

    Timothy M. D’Alfonso

    2015-07-01

    Full Text Available Inflammatory and reactive lesions of the breast are relatively uncommon among benign breast lesions and can be the source of an abnormality on imaging. Such lesions can simulate a malignant process, based on both clinical and radiographic findings, and core biopsy is often performed to rule out malignancy. Furthermore, some inflammatory processes can mimic carcinoma or other malignancy microscopically, and vice versa. Diagnostic difficulty may arise due to the small and fragmented sample of a core biopsy. This review will focus on the pertinent clinical, radiographic, and histopathologic features of the more commonly encountered inflammatory lesions of the breast that can be characterized in a core biopsy sample. These include fat necrosis, mammary duct ectasia, granulomatous lobular mastitis, diabetic mastopathy, and abscess. The microscopic differential diagnoses for these lesions when seen in a core biopsy sample will be discussed.

  1. A Review of Inflammatory Processes of the Breast with a Focus on Diagnosis in Core Biopsy Samples.

    Science.gov (United States)

    D'Alfonso, Timothy M; Ginter, Paula S; Shin, Sandra J

    2015-07-01

    Inflammatory and reactive lesions of the breast are relatively uncommon among benign breast lesions and can be the source of an abnormality on imaging. Such lesions can simulate a malignant process, based on both clinical and radiographic findings, and core biopsy is often performed to rule out malignancy. Furthermore, some inflammatory processes can mimic carcinoma or other malignancy microscopically, and vice versa. Diagnostic difficulty may arise due to the small and fragmented sample of a core biopsy. This review will focus on the pertinent clinical, radiographic, and histopathologic features of the more commonly encountered inflammatory lesions of the breast that can be characterized in a core biopsy sample. These include fat necrosis, mammary duct ectasia, granulomatous lobular mastitis, diabetic mastopathy, and abscess. The microscopic differential diagnoses for these lesions when seen in a core biopsy sample will be discussed.

  2. Overview of the COMPASS diagnostics

    Czech Academy of Sciences Publication Activity Database

    Weinzettl, Vladimír; Pánek, Radomír; Hron, Martin; Stöckel, Jan; Žáček, František; Havlíček, Josef; Bílková, Petra; Naydenkova, Diana; Háček, Pavel; Zajac, Jaromír; Dejarnac, Renaud; Horáček, Jan; Adámek, Jiří; Mlynář, Jan; Janky, Filip; Aftanas, Milan; Böhm, Petr; Brotánková, Jana; Šesták, David; Ďuran, Ivan; Melich, Radek; Jareš, Daniel; Anda, B.; Veres, G.; Szappanos, A.; Zoletnik, S.; Berta, M.; Shevchenko, V. F.; Scannell, R.; Walsh, D.; Müller, H. W.; Igochine, V.; Silva, A.; Manso, M.; Gomes, R.; Popov, Tsv.; Sarychev, D.; Kiselov, V.K.; Nanobashvili, S.; Ghosh, J.

    2011-01-01

    Roč. 86, 6-8 (2011), s. 1227-1231 ISSN 0920-3796. [Symposium of Fusion Technology (SOFT-26). Porto, 27.09.2010-01.10.2010] R&D Projects: GA ČR GA202/09/1467; GA ČR GA202/08/0419; GA ČR GD202/08/H057; GA AV ČR KJB100430901; GA MŠk 7G09042 Institutional research plan: CEZ:AV0Z20430508 Keywords : plasma diagnostics * tokamak * COMPASS Subject RIV: BL - Plasma and Gas Discharge Physics Impact factor: 1.490, year: 2011 http://www.sciencedirect.com/science/article/pii/S0920379610005594

  3. SCDAP: a light water reactor computer code for severe core damage analysis

    International Nuclear Information System (INIS)

    Marino, G.P.; Allison, C.M.; Majumdar, D.

    1982-01-01

    Development of the first code version (MODO) of the Severe Core Damage Analysis Package (SCDAP) computer code is described, and calculations made with SCDAP/MODO are presented. The objective of this computer code development program is to develop a capability for analyzing severe disruption of a light water reactor core, including fuel and cladding liquefaction, flow, and freezing; fission product release; hydrogen generation; quenched-induced fragmentation; coolability of the resulting geometry; and ultimately vessel failure due to vessel-melt interaction. SCDAP will be used to identify the phenomena which control core behavior during a severe accident, to help quantify uncertainties in risk assessment analysis, and to support planning and evaluation of severe fuel damage experiments and data. SCDAP/MODO addresses the behavior of a single fuel bundle. Future versions will be developed with capabilities for core-wide and vessel-melt interaction analysis

  4. The Kinematics of Molecular Cloud Cores in the Presence of Driven and Decaying Turbulence: Comparisons with Observations

    Energy Technology Data Exchange (ETDEWEB)

    Offner, S R; Krumholz, M R; Klein, R I; McKee, C F

    2007-12-17

    In this study we investigate the formation and properties of prestellar and protostellar cores using hydrodynamic, self-gravitating Adaptive Mesh Refinement simulations, comparing the cases where turbulence is continually driven and where it is allowed to decay. We model observations of these cores in the C{sup 18}O(2 {yields} 1), NH{sub 3}(1, 1), and N{sub 2}H{sup +}(1 {yields} 0) lines, and from the simulated observations we measure the linewidths of individual cores, the linewidths of the surrounding gas, and the motions of the cores relative to one another. Some of these distributions are significantly different in the driven and decaying runs, making them potential diagnostics for determining whether the turbulence in observed star-forming clouds is driven or decaying. Comparing our simulations with observed cores in the Perseus and {rho} Ophiuchus clouds shows reasonably good agreement between the observed and simulated core-to-core velocity dispersions for both the driven and decaying cases. However, we find that the linewidths through protostellar cores in both simulations are too large compared to the observations. The disagreement is noticeably worse for the decaying simulation, in which cores show highly supersonic in fall signatures in their centers that decrease toward their edges, a pattern not seen in the observed the regions.

  5. 77 FR 41273 - Core Values and Characteristics of the Department

    Science.gov (United States)

    2012-07-13

    ... single worker plays a critical role in supporting the overall strategic vision and mission of the agency..., most importantly, become an enduring part of the VA culture. The ``I CARE'' logo will be prominently... all the time, the Core Values and Characteristics are meant to endure. There are no immediate plans to...

  6. Engineering task plan for rotary mode core sampling exhausters CAM high radiation interlock

    International Nuclear Information System (INIS)

    BOGER, R.M.

    1999-01-01

    The Rotary Mode Core Sampling (RMCS) system is primarily made up of the Rotary Mode Core Sample Trucks (RMCST) and the RMCS Exhausters. During RMCS operations an Exhauster is connected to a tank riser and withdraws gases from the tank dome vapor space at approximately 200 Standard Cubic Feet per Minute (SCFM). The gases are passed through two High Efficiency Particulate Air (HEPA) filters before passing out the exhaust stack to the atmosphere. A Continuous Air Monitor (CAM) monitors the exhaust gases in the exhaust stack for beta particle and gamma radiation. The CAM has a high radiation alarm output and a detector fail alarm output. The CAM alarms are currently connected to the data logger only. The CAM alarms require operator response per procedure LMHC 1998 but no automatic functions are initiated by the CAM alarms. Currently, there are three events that can cause an automatic shut down of the Exhauster. These are, Low Tank Pressure, Highnow Stack Flow and High HEPA Filter Differential Pressure (DP)

  7. Minimally invasive breast surgery: vacuum-assisted core biopsy

    Directory of Open Access Journals (Sweden)

    A. V. Goncharov

    2017-01-01

    Full Text Available Fibrocystic breast disease is diagnosed in 20 % of women. Morphological verification of breast lumps is an important part of monitoring of these patients.Study objective. To study the role of vacuum-assisted core biopsy (VAB in differential diagnosis of fibrocystic breast disease.Materials and methods. In 2014 in Innomed plus clinic the VAB method for tumor diagnostics was introduced for the first time in the PrimorskyRegion. We studied application of VAB in 22 patients with a diagnosis of nonpalpable breast lesion.Results. Relapse rate for VAB is 4.5 %, complication rate in the form of postoperative hematomas is 22.7 %, but these complications do not increase duration of rehabilitation and are not clinically relevant.Conclusion. VAB is a minimally invasive surgical approach which allows to collect the same volume of tumor tissue as sectoral resection. The benefits of the method are better cosmetic results and shorter rehabilitation period with comparable complication rate. This allows to use VAB not only for diagnostic purposes but as a treatment for benign breast tumors.

  8. Virtual Learning Factory on VR-Supported Factory Planning

    OpenAIRE

    Weidig , Christian; Menck , Nicole; Winkes , Pascal ,; Aurich , Jan ,

    2014-01-01

    Part 13: Virtual Reality and Simulation; International audience; Learning Factories are becoming popular as tangible measures to teach engineering methods while making use of them in an industrial-like environment. Their core component is usually a factory demonstrator, users are physically working with. For factory planning such approaches can hardly be adapted, due to long lasting realization phases.To overcome this obstacle a virtual learning factory has been developed whose core component...

  9. Planning successful change incorporating processes and people.

    Science.gov (United States)

    Hewitt-Taylor, Jaqui

    Implementing change is a core element of developing healthcare practice. While planning the practical aspects of change is vital, so too is considering how people will perceive and be affected by an innovation, including what individuals and teams will gain or lose, who the opinion leaders will be and the influence of workplace culture. The aim of this article is to highlight some of the considerations that may be useful in planning successful change.

  10. Earth's inner core: Innermost inner core or hemispherical variations?

    NARCIS (Netherlands)

    Lythgoe, K. H.; Deuss, A.|info:eu-repo/dai/nl/412396610; Rudge, J. F.; Neufeld, J. A.

    2014-01-01

    The structure of Earth's deep inner core has important implications for core evolution, since it is thought to be related to the early stages of core formation. Previous studies have suggested that there exists an innermost inner core with distinct anisotropy relative to the rest of the inner core.

  11. Dependence of Core and Extended Flux on Core Dominance ...

    Indian Academy of Sciences (India)

    Abstract. Based on two extragalactic radio source samples, the core dominance parameter is calculated, and the correlations between the core/extended flux density and core dominance parameter are investi- gated. When the core dominance parameter is lower than unity, it is linearly correlated with the core flux density, ...

  12. Core design aspects of SNR 2

    International Nuclear Information System (INIS)

    Wehmann, U.K.

    1987-01-01

    The paper describes in its first part the main characteristics of the core of the SNR 2 fast breeder reactor which is being planned within the European collaboration on fast breeder reactors. In the second part some core design aspects are discussed. The fuel element management with an inwards shuffling after each cycle is illustrated which offers advantages with respect to linear rating, steel damage and average discharge burnup. For this management, the full three-dimensional power and burnup history has been calculated and some typical results are presented. The shutdown requirements and the capabilities of the two shutdown systems of SNR 2 are discussed. The necessity for a reliable surveillance of the power distribution is demonstrated by the pronounced power tilts in case of the unintentional withdrawal of an absorber rod. Finally, a short review of the main nuclear design methods and their validation with help of the evaluation of experiments in zero power facilities and power reactors is given

  13. AAPT Diagnostic Criteria for Chronic Cancer Pain Conditions.

    Science.gov (United States)

    Paice, Judith A; Mulvey, Matt; Bennett, Michael; Dougherty, Patrick M; Farrar, John T; Mantyh, Patrick W; Miaskowski, Christine; Schmidt, Brian; Smith, Thomas J

    2017-03-01

    Chronic cancer pain is a serious complication of malignancy or its treatment. Currently, no comprehensive, universally accepted cancer pain classification system exists. Clarity in classification of common cancer pain syndromes would improve clinical assessment and management. Moreover, an evidence-based taxonomy would enhance cancer pain research efforts by providing consistent diagnostic criteria, ensuring comparability across clinical trials. As part of a collaborative effort between the Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities, and Networks (ACTTION) and the American Pain Society (APS), the ACTTION-APS Pain Taxonomy initiative worked to develop the characteristics of an optimal diagnostic system. After the establishment of these characteristics, a working group consisting of clinicians and clinical and basic scientists with expertise in cancer and cancer-related pain was convened to generate core diagnostic criteria for an illustrative sample of 3 chronic pain syndromes associated with cancer (ie, bone pain and pancreatic cancer pain as models of pain related to a tumor) or its treatment (ie, chemotherapy-induced peripheral neuropathy). A systematic review and synthesis was conducted to provide evidence for the dimensions that comprise this cancer pain taxonomy. Future efforts will subject these diagnostic categories and criteria to systematic empirical evaluation of their feasibility, reliability, and validity and extension to other cancer-related pain syndromes. The ACTTION-APS chronic cancer pain taxonomy provides an evidence-based classification for 3 prevalent syndromes, namely malignant bone pain, pancreatic cancer pain, and chemotherapy-induced peripheral neuropathy. This taxonomy provides consistent diagnostic criteria, common features, comorbidities, consequences, and putative mechanisms for these potentially serious cancer pain conditions that can be extended and applied with other cancer

  14. Validation of the production process of core-equipment HYNIC-Bombesin-Sn

    International Nuclear Information System (INIS)

    Rubio C, N. I.

    2008-01-01

    The validation process is establishing documented evidence that provides a high degree of assurance that a specific process consistently will produce a product that will meet specifications and quality attributes preset and, therefore, ensures the efficiency and effectiveness of a product. The radiopharmaceutical 99m Tc-HYNlC-Bombesin is part of the gastrin-releasing peptide (GRP) analogues of bombesin that are radiolabelled with technetium 99 metastable for molecular images obtention. Is obtained from freeze-dry formulations kits (core- equipment)) and has reported a very high stability in human serum, specific binding to receptors and rapid internalization. Biodistribution data in mice showed rapid blood clearance with predominant renal excretion and specific binding to tissues with positive response to GRP receptors. According to biokinetics studies performed on patients with breast cancer, breast show a marked asymmetry with increased uptake in neoplastic breast in healthy women and the uptake of radiopharmaceuticals is symmetrical in both breasts. No reported adverse reactions. In this paper, the prospective validation core-equipment HYNlC-Bombesin-Sn, which was shown consistently that the product meets the specifications and quality, attributes to preset from the obtained from the diagnostic radiopharmaceutical third generation: 99m Tc-HYNlC-Bombesin. The process was successfully validated and thereby ensuring the efficiency and effectiveness of this agent as a preliminary diagnostic for approval to be marketed. (Author)

  15. On-line core monitoring with CORE MASTER / PRESTO

    International Nuclear Information System (INIS)

    Lindahl, S.O.; Borresen, S.; Ovrum, S.

    1986-01-01

    Advanced calculational tools are instrumental in improving reactor plant capacity factors and fuel utilization. The computer code package CORE MASTER is an integrated system designed to achieve this objective. The system covers all main activities in the area of in-core fuel management for boiling water reactors; design, operation support, and on-line core monitoring. CORE MASTER operates on a common data base, which defines the reactor and documents the operating history of the core and of all fuel bundles ever used

  16. Oak Ridge National Laboratory institutional plan, FY 1996--FY 2001

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-01

    This report discusses the institutional plan for Oak Ridge National Laboratory for the next five years. Included in the report are: laboratory director`s statement; laboratory mission, vision, and core competencies; laboratory strategic plan; major laboratory initiatives; scientific and technical programs; critical success factors; summaries of other plans; resource projections; appendix which contains data for site and facilities, user facility, science and mathematic education and human resources; and laboratory organization chart.

  17. Diagnostic Development for ST Plasmas on NSTX

    International Nuclear Information System (INIS)

    Johnson, D.

    2003-01-01

    Spherical tokamaks (STs) have much lower aspect ratio (a/R) and lower toroidal magnetic field, relative to tokamaks and stellarators. This paper will highlight some of the challenges and opportunities these features pose in the diagnosis of ST plasmas on the National Spherical Torus Experiment (NSTX), and discuss some of the corresponding diagnostic development that is underway. The low aspect ratio necessitates a small center stack, with tight space constraints and large thermal excursions, complicating the design of magnetic sensors in this region. The toroidal magnetic field on NSTX is less than or equal to 0.6 T, making it impossible to use ECE as a good monitor of electron temperature. A promising new development for diagnosing electron temperature is electron Bernstein wave (EBW) radiometry, which is currently being pursued on NSTX. A new high-resolution charge exchange recombination spectroscopy system is being installed. Since non-inductive current initiation and sustainment ar e top-level NSTX research goals, measurements of the current profile J(R) are essential to many planned experiments. On NSTX several modifications are planned to adapt the MSE technique to lower field, and two novel MSE systems are being prototyped. Several high speed 2-D imaging techniques are being developed, for viewing both visible and x-ray emission. The toroidal field is comparable to the poloidal field at the outside plasma edge, producing a large field pitch (>50 o ) at the outer mid-plane. The large shear in pitch angle makes some fluctuation diagnostics like beam emission spectroscopy very difficult, while providing a means of achieving spatial localization for microwave scattering investigations of high-k turbulence, which are predicted to be virulent for NSTX plasmas. A brief description of several of these techniques will be given in the context of the current NSTX diagnostic set

  18. Stress ratio determination from the core-disking phenomenon

    International Nuclear Information System (INIS)

    Lehnhoff, T.F.; Stefansson, B.; Thirumalai, K.

    1982-08-01

    The ability to predict in situ stress conditions from standard core samples offers planning and site-selection advantages for most underground facilities. This paper presents an empirical relation for estimating the horizontal to vertical stress ratio in basalt. The resulting estimates can then be used to help assess the extent to which measurement of in situ stress is required. The core disking phenomenon has long been used as an indicator of high in situ stress. It is concluded that disks form as the result of tensile failure initiation rather than shear failure initiation of the core. It is deduced that the tensile failure begins at the edge of the core and propagates toward the center in shear rather than beginning at the center and propagating outward. An empirical relation for horizontal to vertical stress ratio variation with depth has been developed and is shown to agree substantially with previous measured horizontal to vertical stress ratios for locations in several areas of the world. The stress-ratio predictions are justified based on finite-element studies using linear elastic analysis and also nonlinear (tension cut-off) analysis. Indications of fracture propagation paths were determined from the analyses. The shape of the predicted propagation path agrees well with physical observations

  19. In vessel core melt progression phenomena

    International Nuclear Information System (INIS)

    Courtaud, M.

    1993-01-01

    For all light water reactor (LWR) accidents, including the so called severe accidents where core melt down can occur, it is necessary to determine the amount and characteristics of fission products released to the environment. For existing reactors this knowledge is used to evaluate the consequences and eventual emergency plans. But for future reactors safety authorities demand decrease risks and reactors designed in such a way that fission products are retained inside the containment, the last protective barrier. This requires improved understanding and knowledge of all accident sequences. In particular it is necessary to be able to describe the very complex phenomena occurring during in vessel core melt progression because they will determine the thermal and mechanical loads on the primary circuit and the timing of its rupture as well as the fission product source term. On the other hand, in case of vessel failure, knowledge of the physical and chemical state of the core melt will provide the initial conditions for analysis of ex-vessel core melt progression and phenomena threatening the containment. Finally a good understanding of in vessel phenomena will help to improve accident management procedures like Emergency Core Cooling System water injection, blowdown and flooding of the vessel well, with their possible adverse effects. Research and Development work on this subject was initiated a long time ago and is still in progress but now it must be intensified in order to meet the safety requirements of the next generation of reactors. Experiments, limited in scale, analysis of the TMI 2 accident which is a unique source of global information and engineering judgment are used to establish and assess physical models that can be implemented in computer codes for reactor accident analysis

  20. Self-Organization Observed in Numerical Simulations of a Hard-Core Diffuse Z Pinch

    International Nuclear Information System (INIS)

    Makhin, V; Siemon, R E; Bauer, B S; Esaulov, A; Lindemuth, I R; Ryutov, D D; Sheehey, P T; Sotnikov, V I

    2005-04-01

    The evolution of an unstable plasma profile into a stable profile, which we term self-organization, appears to be a robust process. Although it was not termed self organization, the same effect has been noted in past simulations with the same code. The result has been made easier to discern by the introduction of z-averaged profiles. A recent report of PIC simulations in the hard-core z-pinch configuration also shows self-organization. Figures 3 and 4 in Reference 21 show how pressure profiles in a low-β PIC simulation relax from unstable to stable. The non-linear evolution of the interchange motion has been studied under controlled initial conditions that result in exponential growth of a mode with a prescribed axial wavelength. An interesting feature of such growth is an abrupt transition from coherent to incoherent motion, after which the z-averaged pressure, current, and temperature profiles become quasi stationary. According to our understanding of MAGO experiments, the observed plasma behavior is consistent with the expectation of self-organization, but the diagnostics are not sufficiently detailed thus far to make a definite conclusion. The results of this simulations reported in this paper add motivation to planned experiments on an inverse pinch at UNR

  1. Development of Core Design Technology for LMR

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Yeong Il; Hong, S. G.; Jang, J. W. (and others)

    2007-06-15

    This report describes the contents of core design technology and computer code system development performed during 2005 and 2006 on the objects of nuclear proliferation resistant core and nuclear fuel basic key technology development security. Also, it is including the future application plans for the results and the developed methodology, important information and the materials acquired in this period. Two core designs with single enrichment were considered for the KALIMER-600 during the first year : 1) the first core uses the non-fuel rods such as B4C, ZrH1.8, and dummy rods, 2) the core using different cladding thickness for each core region (inner, middle, and outer cores) without non-fuel rods to flatten the power distribution. In particular, the latter design was intended to simplify the fuel assembly design by eliminating the heterogeneity. It was found that the proposed design satisfy all of the Gen IV SFR design goals on the cycle length longer than 18 EFPM, fuel discharge burnup larger than 80GWd/t, sodium void worth, conversion ratio, reactivity burnup swing and so on. For this object reactor, the structure integrity outside of reactor is confirmed for the radiation exposure during the plant life according to the result of shielding design and evaluation. The transmutation capability and the core characteristics of sodium cooled fast reactor was also evaluated according to the change of MA amount. The reactivity coefficients for the BN-600 reactor with MA fueled are calculated and the results are compared and evaluated with other participants results. Even though the discrepancies between the results of participants are somewhat large but the K-CORE results are close to the average within a standard deviation. To have the capability of 3-dimensional core dynamic analysis such as analyzing power distribution and reactivity variations according to the asymmetric insertion/withdrawal of control rods, the calculation module for core dynamic parameters was

  2. Core OCD Symptoms: Exploration of Specificity and Relations with Psychopathology

    Science.gov (United States)

    Stasik, Sara M.; Naragon-Gainey, Kristin; Chmielewski, Michael; Watson, David

    2012-01-01

    Obsessive-compulsive disorder (OCD) is a heterogeneous condition, comprised of multiple symptom domains. This study used aggregate composite scales representing three core OCD dimensions (Checking, Cleaning, Rituals), as well as Hoarding, to examine the discriminant validity, diagnostic specificity, and predictive ability of OCD symptom scales. The core OCD scales demonstrated strong patterns of convergent and discriminant validity – suggesting that these dimensions are distinct from other self-reported symptoms – whereas hoarding symptoms correlated just as strongly with OCD and non-OCD symptoms in most analyses. Across analyses, our results indicated that Checking is a particularly strong, specific marker of OCD diagnosis, whereas the specificity of Cleaning and Hoarding to OCD was less strong. Finally, the OCD Checking scale was the only significant predictor of OCD diagnosis in logistic regression analyses. Results are discussed with regard to the importance of assessing OCD symptom dimensions separately and implications for classification. PMID:23026094

  3. Turning the Page: Advancing Paper-Based Microfluidics for Broad Diagnostic Application.

    Science.gov (United States)

    Gong, Max M; Sinton, David

    2017-06-28

    Infectious diseases are a major global health issue. Diagnosis is a critical first step in effectively managing their spread. Paper-based microfluidic diagnostics first emerged in 2007 as a low-cost alternative to conventional laboratory testing, with the goal of improving accessibility to medical diagnostics in developing countries. In this review, we examine the advances in paper-based microfluidic diagnostics for medical diagnosis in the context of global health from 2007 to 2016. The theory of fluid transport in paper is first presented. The next section examines the strategies that have been employed to control fluid and analyte transport in paper-based assays. Tasks such as mixing, timing, and sequential fluid delivery have been achieved in paper and have enabled analytical capabilities comparable to those of conventional laboratory methods. The following section examines paper-based sample processing and analysis. The most impactful advancement here has been the translation of nucleic acid analysis to a paper-based format. Smartphone-based analysis is another exciting development with potential for wide dissemination. The last core section of the review highlights emerging health applications, such as male fertility testing and wearable diagnostics. We conclude the review with the future outlook, remaining challenges, and emerging opportunities.

  4. MODERN CAPABILITIES OF BREAST PATHOLOGY DIAGNOSTICS

    Directory of Open Access Journals (Sweden)

    I. V. Vysotskaya

    2015-01-01

    Full Text Available Every year more than 1 million new cases of breast cancer are being recorded worldwide. Choice of appropriate tactics of treatment depends on the timely diagnosis and correct assessment of the prevalence of cancer.The algorithm of patient»s examination includes clinical examination, X-ray mammography and ultrasonic diagnosis of breast. However, this is not sufficient for a complete interpretation of the patient»s condition in case of non-palpable breast formations, ambiguous interpretation of imaging under structural changes, increased density of breast tissue, etc.In this regard, the introduction of new technologies and their evaluation in terms of practicality is a logical and developing method of early diagnosis of breast pathology.One of the methods that enables enhancing the information capability of ultrasonic diagnosis of breast is elastography. It allows for the differential diagnosis of benign and malignant changes not only in the breast tissue, but also in the areas of regional lymph drainage.Promising method of modern diagnostic breast care is digital mammography tomosynthesis. However, in spite of the first and very optimisticdata, this technique is still far from standard.Complex diagnostics of breast pathology, in addition to clinical data and imaging results, are based on information obtained from biopsies. At the present stage core-biopsy is considered as the best way of verification, where the resulting material is subjected to immunohistochemical studies.Thus, the spectrum of diagnostic capabilities is constantly expanding. Highly informative techniques included in the daily practice today enable clinicians to achieve optimal results in curing even greater number of patients.

  5. Newly discovered young CORE-SINEs in marsupial genomes.

    Science.gov (United States)

    Munemasa, Maruo; Nikaido, Masato; Nishihara, Hidenori; Donnellan, Stephen; Austin, Christopher C; Okada, Norihiro

    2008-01-15

    Although recent mammalian genome projects have uncovered a large part of genomic component of various groups, several repetitive sequences still remain to be characterized and classified for particular groups. The short interspersed repetitive elements (SINEs) distributed among marsupial genomes are one example. We have identified and characterized two new SINEs from marsupial genomes that belong to the CORE-SINE family, characterized by a highly conserved "CORE" domain. PCR and genomic dot blot analyses revealed that the distribution of each SINE shows distinct patterns among the marsupial genomes, implying different timing of their retroposition during the evolution of marsupials. The members of Mar3 (Marsupialia 3) SINE are distributed throughout the genomes of all marsupials, whereas the Mac1 (Macropodoidea 1) SINE is distributed specifically in the genomes of kangaroos. Sequence alignment of the Mar3 SINEs revealed that they can be further divided into four subgroups, each of which has diagnostic nucleotides. The insertion patterns of each SINE at particular genomic loci, together with the distribution patterns of each SINE, suggest that the Mar3 SINEs have intensively amplified after the radiation of diprotodontians, whereas the Mac1 SINE has amplified only slightly after the divergence of hypsiprimnodons from other macropods. By compiling the information of CORE-SINEs characterized to date, we propose a comprehensive picture of how SINE evolution occurred in the genomes of marsupials.

  6. 2012 HIV Diagnostics Conference: the molecular diagnostics perspective.

    Science.gov (United States)

    Branson, Bernard M; Pandori, Mark

    2013-04-01

    2012 HIV Diagnostic Conference Atlanta, GA, USA, 12-14 December 2012. This report highlights the presentations and discussions from the 2012 National HIV Diagnostic Conference held in Atlanta (GA, USA), on 12-14 December 2012. Reflecting changes in the evolving field of HIV diagnostics, the conference provided a forum for evaluating developments in molecular diagnostics and their role in HIV diagnosis. In 2010, the HIV Diagnostics Conference concluded with the proposal of a new diagnostic algorithm which included nucleic acid testing to resolve discordant screening and supplemental antibody test results. The 2012 meeting, picking up where the 2010 meeting left off, focused on scientific presentations that assessed this new algorithm and the role played by RNA testing and new developments in molecular diagnostics, including detection of total and integrated HIV-1 DNA, detection and quantification of HIV-2 RNA, and rapid formats for detection of HIV-1 RNA.

  7. VALIDITY OF CORE NEEDLE BIOPSY IN THE HISTOPATHOLOGICAL VERIFICATION OF PAROTID GLAND LESIONS

    Directory of Open Access Journals (Sweden)

    Oroz Aleksandar

    2016-07-01

    Full Text Available Background and purpose: An adequate diagnosis of a parotid gland enlargement is crucial for an appropriate treatment. The aim of the study was to evaluate effectiveness and minimal invasiveness of diagnostic procedures of core-needle biopsy. Materials and Methods: This study involved 67 patients, aged 40 to 90 years, with a tumor mass in the submandibular and parotid region. Method used for taking samples of pathological masses was BD Disposable guillotine spring-loaded needle for biopsies on soft tissues. Final diagnoses were established on the basis of surgical-pathological results in 67 cases, and on the basis of histopathological analysis of core-biopsy samples. Results: Compared with results of surgical biopsy, core-needle biopsy had sensitivity of 100% in differentiating benign from malignant lesions and in setting up an adequate diagnosis. Its positive predictive values were 100% in diagnosing malignancy. There were found 28 non-malignant and 39 malignant lesions with fewer disadvantages for patients.

  8. Prediction and Optimization of Key Performance Indicators in the Production of Stator Core Using a GA-NN Approach

    Science.gov (United States)

    Rajora, M.; Zou, P.; Xu, W.; Jin, L.; Chen, W.; Liang, S. Y.

    2017-12-01

    With the rapidly changing demands of the manufacturing market, intelligent techniques are being used to solve engineering problems due to their ability to handle nonlinear complex problems. For example, in the conventional production of stator cores, it is relied upon experienced engineers to make an initial plan on the number of compensation sheets to be added to achieve uniform pressure distribution throughout the laminations. Additionally, these engineers must use their experience to revise the initial plans based upon the measurements made during the production of stator core. However, this method yields inconsistent results as humans are incapable of storing and analysing large amounts of data. In this article, first, a Neural Network (NN), trained using a hybrid Levenberg-Marquardt (LM) - Genetic Algorithm (GA), is developed to assist the engineers with the decision-making process. Next, the trained NN is used as a fitness function in an optimization algorithm to find the optimal values of the initial compensation sheet plan with the aim of minimizing the required revisions during the production of the stator core.

  9. Sampling and analysis plan for the gunite and associated tanks interim remedial action, wall coring and scraping at Oak Ridge National Laboratory, Oak Ridge, Tennessee

    International Nuclear Information System (INIS)

    1998-02-01

    This Sampling and Analysis Plan documents the procedures for collecting and analyzing wall core and wall scraping samples from the Gunite and Associated Tanks. These activities are being conducted to support the Comprehensive Environmental Response, Compensation, and Liability Act at the gunite and associated tanks interim remedial action at Oak Ridge National Laboratory in Oak Ridge, Tennessee. The sampling and analysis activities will be performed in concert with sludge retrieval and sluicing of the tanks. Wall scraping and/or wall core samples will be collected from each quadrant in each tank by using a scraping sampler and/or a coring drill deployed by the Houdini robot vehicle. Each sample will be labeled, transported to the Radioactive Materials Analytical Laboratory, and analyzed for physical and radiological characteristics, including total activity, gross alpha, gross beta, radioactive strontium and cesium, and other alpha- and gamma-emitting radionuclides. The data quality objectives process, based on US Environmental Protection Agency guidance, was applied to identify the objectives of this sampling and analysis. The results of the analysis will be used to (1) validate predictions of a strontium concrete diffusion model, (2) estimate the amount of radioactivity remaining in the tank shells, (3) provide information to correlate with measurements taken by the Gunite Tank Isotope Mapping Probe and the Characterization End Effector, and (4) estimate the performance of the wall cleaning system. This revision eliminates wall-scraping samples from all tanks, except Tank W-3. The Tank W-3 experience indicated that the wall scrapper does not collect sufficient material for analysis

  10. Restraint system for core elements of a reactor core

    International Nuclear Information System (INIS)

    Class, G.

    1975-01-01

    In a nuclear reactor, a core element bundle formed of a plurality of side-by-side arranged core elements is surrounded by restraining elements that exert a radially inwardly directly restraining force generating friction forces between the core elements in a restraining plane that is transverse to the core element axes. The adjoining core elements are in rolling contact with one another in the restraining plane by virtue of rolling-type bearing elements supported in the core elements. (Official Gazette)

  11. The influence of cephalometrics on orthodontic treatment planning

    NARCIS (Netherlands)

    Nijkamp, P.G.; Habets, L.L.M.H.; Aartman, I.H.A.; Zentner, A.

    2008-01-01

    SUMMARY Since its introduction, cephalometrics, i.e. cephalometric radiography and analysis, has been used for orthodontic treatment planning. However, the effectiveness of this diagnostic method remains questionable. A randomized crossover study was designed to assess the infl uence of

  12. Final report for Tank 241-B-101, push mode cores 90 and 91. Revision 1

    International Nuclear Information System (INIS)

    Schreiber, R.D.

    1995-11-01

    This is the final report for tank 241-at sign 101, cores 90 and 91. Samples from these cores were analyzed for safety screening purposes in accordance with the Tank 241-B-101 Tank Characterization Plan (TCP) (Reference 1). This final report contains the results for three sets of TGA and gravimetric analyses performed after the 90-day report was issued. Two of these TGA/gravimetric percent water sets of analyses were done because low original TGA results were obtained for the lower half segment of core 90, segment 2 and the facie of core 91, segment 2; the third set of analyses were performed because the TGA and gravimetric percent water results for the upper half segment of core 90, segment 2 differed by approximately a factor of three and further investigation was warranted

  13. Environmental mining plan of the construction materials industry in Cartagena, Phase 1 Diagnostic. Vol.1 and Vol.2(Annex)

    International Nuclear Information System (INIS)

    Castiblanco, Carmen Rosa; Franco Serna, Jose Vicente; Nino, Jaime

    1996-01-01

    INGEOMINAS carried out this project in the cities of Cartagena, Bucaramanga, Cali and Bogota, in two phases: Phase 1 (Diagnostic) and Phase II (Formulation of Handling Plan). The phase 1 that here is described, it upgrades the knowledge of the extractive industry of the construction materials for the city of Cartagena, through bibliographical revision and field work, carried out in 50 quarries that supply from these materials to the city. This study, besides the economic and legal handling, identifies technical aspects related with the geology, the mining and the environmental situation. In accordance with their likeness, geologic, morphological and of exploitation (extraction methods and mining development), the quarries met in five groups: Exploitations on calcareous deposits of the La Popa Formation, exploitations on clay deposits of the La Popa Formation, exploitations on detritus deposits of half grain to thick (La Popa-Arenosa Formation; Pendales Conglomerate and Rotinet Formation) and exploitation of calcareous of the Arroyo de Piedra Formation. The extraction of these materials is characterized by its low degree of development technician, lack of planning mining, lack of appropriate infrastructure that allows a better development of the sector, is also evident the control lack on the part of the entities in charge of the handling of this industry. These factors added to a demand every time in increase of these materials, they have taken to a progressive deterioration in the landscape, increase of the noise and particles in the air and in the waters. The low control in this activity has generated the proliferation of informal exploitations that they find in this activity a way of subsistence

  14. Advanced probes for edge plasma diagnostics on the CASTOR tokamak

    Czech Academy of Sciences Publication Activity Database

    Stöckel, Jan; Adámek, Jiří; Balan, P.; Hronová-Bilyková, Olena; Brotánková, Jana; Dejarnac, Renaud; Devynck, P.; Ďuran, Ivan; Gunn, J. P.; Hron, Martin; Horáček, Jan; Ionita, C.; Kocan, M.; Martines, E.; Pánek, Radomír; Peleman, P.; Schrittwieser, R.; Van Oost, G.; Žáček, František

    2006-01-01

    Roč. 63, č. 0 (2006), 012001-012002 E-ISSN 1742-6596. [SECOND INTERNATIONAL WORKSHOP AND SUMMER SCHOOL ON PLASMA PHYSICS. Kiten, 03.07.2006-09.07.2006] R&D Projects: GA AV ČR KJB100430504 Institutional research plan: CEZ:AV0Z20430508 Keywords : plasma * tokamak * electric probes * diagnostics Subject RIV: BL - Plasma and Gas Discharge Physics

  15. Detection of binaries in the core of the globular cluster M15 using calcium emission lines

    Energy Technology Data Exchange (ETDEWEB)

    Murphy, B W [Rijksuniversiteit Utrecht (Netherlands). Inst. of Astronomy; Rutten, R G.M. [Astronomical Inst. ' Anton Pannekoek' , Amsterdam (Netherlands); Callanan, P J [Oxford Univ. (UK). Dept. of Astrophysics; Seitzer, Patrick [Space Telescope Science Inst., Baltimore, MD (USA); Charles, P A [Oxford Univ. (UK). Dept. of Astrophysics Observatorio del Roque do los Muchachos, Santa Cruz de La Palma, Tenerife, Canary Islands (Spain); Cohn, H N; Lugger, P M [Indiana Univ., Bloomington, IN (USA). Dept. of Astronomy

    1991-05-09

    M12 is the prototypical collapsed-core globular cluster. Having undergone collapse, its core is believed now to be expanding, with energy for the re-expansion provided by binary stars, which turn gravitational potential energy into kinetic energy. Because these binary stars are generally more massive than single stars, they will have settled to the centre of the cluster. We report here that several of the stars at the core of M15 show Ca II H- and K-line emission characteristic of young, rapidly rotating stars and close binaries. We argue that the emission from M15 comes from primordial binaries, in which a period of spin-up has led to magnetic field generation by enhanced dynamo action, which in turn causes heating of the stellar chromospheres. If this interpretation is correct, the Ca H and K emission may provide an important diagnostic tool of the binary population in cluster cores, and thus of the cluster dynamics. (author).

  16. Detection of binaries in the core of the globular cluster M15 using calcium emission lines

    International Nuclear Information System (INIS)

    Murphy, B.W.; Callanan, P.J.; Charles, P.A.; Cohn, H.N.; Lugger, P.M.

    1991-01-01

    M12 is the prototypical collapsed-core globular cluster. Having undergone collapse, its core is believed now to be expanding, with energy for the re-expansion provided by binary stars, which turn gravitational potential energy into kinetic energy. Because these binary stars are generally more massive than single stars, they will have settled to the centre of the cluster. We report here that several of the stars at the core of M15 show Ca II H- and K-line emission characteristic of young, rapidly rotating stars and close binaries. We argue that the emission from M15 comes from primordial binaries, in which a period of spin-up has led to magnetic field generation by enhanced dynamo action, which in turn causes heating of the stellar chromospheres. If this interpretation is correct, the Ca H and K emission may provide an important diagnostic tool of the binary population in cluster cores, and thus of the cluster dynamics. (author)

  17. The National Ignition Facility (NIF) Diagnostic Set at the Completion of the National Ignition Campaign (NIC) September 2013

    Energy Technology Data Exchange (ETDEWEB)

    Kilkenny, J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Bell, P. E. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Bradley, D. K. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Bleuel, D. L. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Caggiano, J. A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Dewald, E. L. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Hsing, W. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Kalantar, H. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Kauffman, R. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Moody, J. D. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Schneider, M. B. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Shaughnessy, D. A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Shelton, R. T. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Yeamans, C. B. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Batha, S. H. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Grim, G. P. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Herrmann, H. W. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Merrill, F. E. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Leeper, R. J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Sangster, T. C. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Edgell, D. H. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Glebov, V. Y. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Regan, S. P. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Frenje, J. A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Gatu-Johnson, M. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Petrasso, R. D. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Rindernecht, H. G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Zylstra, A. B. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Cooper, G. W. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Ruiz, C. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2015-01-05

    At the completion of the National Ignition Campaign NIF had about 36 different types of diagnostics. These were based on several decades of development on Nova and OMEGA and involved the whole US ICF community. A plan for a limited of NIF Diagnostics was documented by the Joint Central Diagnostic Team in the NIF Conceptual Design Report in 1994. These diagnostics and many more were installed diagnostics by two decades later. We give a short description of each of the 36 different types of NIC diagnostics grouped by the function of the diagnostics, namely target drive, target response and target assembly, stagnation and burn. A comparison of NIF diagnostics with the Nova diagnostics shows that the NIF diagnostic capability is broadly equivalent to that of Nova’s in 1999. NIF diagnostics have a much greater degree of automation and rigor than Nova’s and the NIF diagnostic suite incorporates some scientific innovation compared to Nova and OMEGA namely one much higher speed x-ray imager. Directions for future NIF diagnostics are discussed.

  18. Severe Accident Research Program plan update

    International Nuclear Information System (INIS)

    1992-12-01

    In August 1989, the staff published NUREG-1365, ''Revised Severe Accident Research Program Plan.'' Since 1989, significant progress has been made in severe accident research to warrant an update to NUREG-1365. The staff has prepared this SARP Plan Update to: (1) Identify those issues that have been closed or are near completion, (2) Describe the progress in our understanding of important severe accident phenomena, (3) Define the long-term research that is directed at improving our understanding of severe accident phenomena and developing improved methods for assessing core melt progression, direct containment heating, and fuel-coolant interactions, and (4) Reflect the growing emphasis in two additional areas--advanced light water reactors, and support for the assessment of criteria for containment performance during severe accidents. The report describes recent major accomplishments in understanding the underlying phenomena that can occur during a severe accident. These include Mark I liner failure, severe accident scaling methodology, source term issues, core-concrete interactions, hydrogen transport and combustion, TMI-2 Vessel Investigation Project, and direct containment heating. The report also describes the major planned activities under the SARP over the next several years. These activities will focus on two phenomenological issues (core melt progression, and fuel-coolant interactions and debris coolability) that have significant uncertainties that impact our understanding and ability to predict severe accident phenomena and their effect on containment performance SARP will also focus on severe accident code development, assessment and validation. As the staff completes the research on severe accident issues that relate to current generation reactors, continued research will focus on efforts to independently evaluate the capability of new advanced light water reactor designs to withstand severe accidents

  19. An overview of SST-1 diagnostics and results from recent campaigns

    International Nuclear Information System (INIS)

    Kumar, Ajai; Adhiya, Asha N.; Joshi, Hemchandra C.

    2015-01-01

    SST-1 is a large aspect ratio tokomak with superconducting magnets designed to operate in steady-state mode for around 1000 seconds. All essential diagnostics for the machine operation and advance diagnostics are commissioned in SST-1 during the different phases of its operation. This report describes the various diagnostics in SST-1 and the results of recent SST-1 campaign with Plasma Facing components. The chord averaged electron density of SST-1 plasma is recorded in the range of 2-5 x 10 12 /cc and the electron temperature is estimated around 100 eV. Various spectral line emissions from plasma and temporal evolutions of some of them have been recorded by spectroscopy diagnostics to understand the impurity behaviour in the SST-1 plasma. The radiation power loss and the power deposited on limiter has been estimated using bolometry and IR thermography respectively. Plasma evolution recorded using visible imaging diagnostics. The energy distribution of non-thermal electron has been characterised using LaBr spectrometer and NaI detector. This article will also be discussing about the possible additions and modification planned for the near future. (author)

  20. The circuit of polychromator for Experimental Advanced Superconducting Tokamak edge Thomson scattering diagnostic

    International Nuclear Information System (INIS)

    Zang, Qing; Zhao, Junyu; Chen, Hui; Li, Fengjuan; Hsieh, C. L.

    2013-01-01

    The detector circuit is the core component of filter polychromator which is used for scattering light analysis in Thomson scattering diagnostic, and is responsible for the precision and stability of a system. High signal-to-noise and stability are primary requirements for the diagnostic. Recently, an upgraded detector circuit for weak light detecting in Experimental Advanced Superconducting Tokamak (EAST) edge Thomson scattering system has been designed, which can be used for the measurement of large electron temperature (T e ) gradient and low electron density (n e ). In this new circuit, a thermoelectric-cooled avalanche photodiode with the aid circuit is involved for increasing stability and enhancing signal-to-noise ratio (SNR), especially the circuit will never be influenced by ambient temperature. These features are expected to improve the accuracy of EAST Thomson diagnostic dramatically. Related mechanical construction of the circuit is redesigned as well for heat-sinking and installation. All parameters are optimized, and SNR is dramatically improved. The number of minimum detectable photons is only 10