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Sample records for plane systolic excursion

  1. Tricuspid annular plane systolic excursion and response to cardiac resynchronization therapy

    DEFF Research Database (Denmark)

    Kjaergaard, Jesper; Ghio, Stefano; St John Sutton, Martin

    2011-01-01

    The aims of this study were to evaluate tricuspid annular plane systolic excursion (TAPSE) as a predictor of left ventricular (LV) reverse remodeling and clinical benefit of cardiac synchronization therapy (CRT) and to evaluate the effect of CRT on TAPSE in patients with mildly symptomatic systol...

  2. Evaluation of tricuspid annular plane systolic excursion measured with cardiac MRI in children with tetralogy of Fallot.

    Science.gov (United States)

    Soslow, Jonathan H; Usoro, Emem; Wang, Li; Parra, David A

    2016-04-01

    Aneurysmal dilation of the right ventricular outflow tract complicates assessment of right ventricular function in patients with repaired tetralogy of Fallot. Tricuspid annular plane systolic excursion is commonly used to estimate ejection fraction. We hypothesised that tricuspid annular plane systolic excursion measured by cardiac MRI approximates global and segmental right ventricular function, specifically right ventricular sinus ejection fraction, in children with repaired tetralogy of Fallot. Tricuspid annular plane systolic excursion was measured retrospectively on cardiac MRIs in 54 patients with repaired tetralogy of Fallot. Values were compared with right ventricular global, sinus, and infundibular ejection fractions. Tricuspid annular plane systolic excursion was indexed to body surface area, converted into a fractional value, and converted into published paediatric Z-scores. Tricuspid annular plane systolic excursion measurements had good agreement between observers. Right ventricular ejection fraction did not correlate with the absolute or indexed tricuspid annular plane systolic excursion and correlated weakly with fractional tricuspid annular plane systolic excursion (r=0.41 and p=0.002). Segmental right ventricular function did not appreciably improve correlation with any of the tricuspid annular plane systolic excursion measures. Paediatric Z-scores were unable to differentiate patients with normal and abnormal right ventricular function. Tricuspid annular plane systolic excursion measured by cardiac MRI correlates poorly with global and segmental right ventricular ejection fraction in children with repaired tetralogy of Fallot. Tricuspid annular plane systolic excursion is an unreliable approximation of right ventricular function in this patient population.

  3. Evaluation of Tricuspid Annular Plane Systolic Excursion Measured with Cardiac Magnetic Resonance Imaging in Pediatric Patients with Tetralogy of Fallot

    Science.gov (United States)

    Soslow, Jonathan H.; Usoro, Emem; Wang, Li; Parra, David A.

    2015-01-01

    Background Aneurysmal dilation of the right ventricular outflow tract complicates assessment of right ventricular function in patients with repaired tetralogy of Fallot. Tricuspid annular plane systolic excursion is commonly used to estimate ejection fraction. We hypothesized that tricuspid annular plane systolic excursion measured by cardiac magnetic resonance imaging approximates global and segmental right ventricular function, specifically right ventricular sinus ejection fraction, in pediatric patients with repaired tetralogy of Fallot. Methods Tricuspid annular plane systolic excursion was measured retrospectively on cardiac magnetic resonance images in 54 patients with repaired tetralogy of Fallot. Values were compared with right ventricular global, sinus, and infundibular ejection fractions. Tricuspid annular plane systolic excursion was: 1) indexed to body surface area, 2) converted into a fractional value, and 3) converted into published pediatric Z-scores. Results Tricuspid annular plane systolic excursion measurements had good agreement between observers. Right ventricular ejection fraction did not correlate with the absolute or indexed tricuspid annular plane systolic excursion and correlated weakly with fractional tricuspid annular plane systolic excursion (r=0.41 and p=0.002). Segmental right ventricular function did not appreciably improve correlation with any of the tricuspid annular plane systolic excursion measures. Pediatric Z-scores were unable to differentiate patients with normal and abnormal right ventricular function. Conclusions Tricuspid annular plane systolic excursion measured on cardiac magnetic resonance imaging correlates poorly with global and segmental right ventricular ejection fraction in pediatric patients with repaired tetralogy of Fallot. Tricuspid annular plane systolic excursion is an unreliable approximation of right ventricular function in this patient population. PMID:26279488

  4. Tricuspid Annular Plane Systolic Excursion and Its Association with Mortality in Critically Ill Patients.

    Science.gov (United States)

    Gajanana, Deepakraj; Seetha Rammohan, Harish; Alli, Oluseun; Romero-Corral, Abel; Purushottam, Bhaskar; Ponamgi, Shiva; Figueredo, Vincent M; Pressman, Gregg S

    2015-08-01

    Transient left ventricular dysfunction can occur under conditions of extreme emotional or physiological stress. There is little data on right ventricular function in such situations. One hundred twenty patients admitted to an ICU with a noncardiac illness were studied. Those with documented coronary disease, ejection fraction <40%, sepsis, or intracranial hemorrhage were excluded. Echocardiograms were performed within 24 hours of admission. Tricuspid annular plane systolic excursion (TAPSE) was measured to assess right ventricular systolic function. Plasma catecholamines (norepinephrine, epinephrine, dopamine) were measured on admission. Clinical and demographic data were collected, along with data on ICU length of stay (LOS), hospital LOS, and in-hospital and long-term mortality. TAPSE was tested for correlation with adverse outcomes and length of stay. Mean TAPSE for the group was 2.05 ± 0.66 cm. Based on area under the ROC curve analysis, TAPSE <2.4 cm was the best cutoff for predicting in-hospital and long-term mortality. There were 13 in-hospital deaths, 12 in the group with TAPSE <2.4 cm and one among those with TAPSE ≥2.4 cm. On multivariate analysis, TAPSE <2.4 cm was a significant predictor of in-hospital mortality (χ(2)  = 4.6, P = 0.03). When tested against hospital LOS, an inverse correlation was found (P = 0.04). No association was found between TAPSE and catecholamine levels. Right ventricular systolic function, as assessed by TAPSE, has important prognostic value in critically ill patients. Mean values were lower in patients who died in-hospital versus those who survived to discharge. In addition, patients with TAPSE <2.4 cm had a longer hospital length of stay. © 2015, Wiley Periodicals, Inc.

  5. Tricuspid Annular Plane Systolic Excursion (TAPSE in a Patient with Pulmonary Emboli

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    Nicole Zawada

    2018-01-01

    Full Text Available History of present illness: A 60-year-old male with a history of pulmonary emboli (PE presented to the emergency department with exertional shortness of breath following a ten-hour flight. The patient admitted to recently stopping his previously prescribed rivaroxaban. His electrocardiogram (ECG showed findings consistent with a S1Q3T3 pattern. Point-of-care ultrasound (POCUS was performed using the curvilinear probe, which revealed a thrombus in the inferior vena cava (IVC. POCUS using the phased array probe demonstrated an abnormal tricuspid annular plane systolic excursion (TAPSE and a significantly dilated right ventricle (RV. Computed tomography angiogram (CTA showed evidence of acute emboli within the right and left distal main pulmonary arteries, left lobar, and left proximal segmental artery. Additionally, a thrombus was visualized in the left distal subhepatic IVC. The patient was admitted to telemetry for anticoagulation and monitoring. Right heart catheterization revealed a significantly elevated pulmonary artery pressure of 95/27. Significant findings: Video 1 and Image 1 show a thrombus in the patient’s IVC. Video 2 and Images 2-3 demonstrate a positive TAPSE of less than 17mm (blue arrow length with a significantly dilated RV, indicating abnormal excursion of the tricuspid annulus and right ventricular dysfunction. Discussion: Pulmonary embolism is the third leading cause of death from cardiovascular disease following myocardial infarction and stroke.1 Approximately half of all PEs are diagnosed in the emergency department2 and early detection and treatment have been shown to improve outcomes and survival.3 Pulmonary emboli can present with a wide range of symptoms including dyspnea, chest pain, shock, or sustained hypotension, and can even be asymptomatic, making it a potentially challenging diagnosis.4 Studies show a high specificity of over 80% but low sensitivity of lower than 60%, for echocardiography in the diagnosis of PE

  6. Predictors of right ventricular function as measured by tricuspid annular plane systolic excursion in heart failure

    DEFF Research Database (Denmark)

    Kjaergaard, Jesper; Iversen, Kasper K; Akkan, Dilek

    2009-01-01

    in heart failure patients, in particular with reduced septal longitudinal motion. TAPSE is decreased in patients with heart failure of ischemic etiology. However, the absolute reduction in TAPSE is small and seems to be of minor importance in the clinical utilization of TAPSE whether applied as a measure...... of right ventricular systolic function or as a prognostic factor....

  7. Tricuspid annular plane systolic excursion in the assessment of right ventricular function in children and adolescents after repair of tetralogy of Fallot.

    Science.gov (United States)

    Mercer-Rosa, Laura; Parnell, Aimee; Forfia, Paul R; Yang, Wei; Goldmuntz, Elizabeth; Kawut, Steven M

    2013-11-01

    Assessing right ventricular (RV) performance is essential for patients with tetralogy of Fallot (TOF). The aim of this study was to investigate the reliability and validity of tricuspid annular plane systolic excursion (TAPSE) against cardiac magnetic resonance imaging measures and cardiopulmonary exercise testing. A retrospective study was performed in 125 outpatients with repaired TOF with available protocol-driven echocardiography, cardiac magnetic resonance imaging, and exercise stress testing obtained as part of a cross-sectional study. TAPSE was measured on the two-dimensional apical four-chamber view on echocardiography by two readers. Multivariate linear regression was used to examine the association between TAPSE and measures of RV function and exercise capacity. The mean age was 12.6 ± 3.3 years, 41 patients (33%) were female, and 104 (83%) were white. TAPSE averaged 1.6 ± 0.37 cm, with an interreader intraclass correlation coefficient of 0.78 (n = 18). TAPSE was significantly associated with cardiac magnetic resonance-based RV stroke volume after adjustment for gender and body surface area (β = 13.8; 95% confidence interval, 2.25-25.30; P = .02). TAPSE was not associated with cardiac magnetic resonance-based RV ejection fraction (P = .77). On exercise testing, TAPSE was not associated with peak oxygen consumption, percentage of predicted oxygen consumption, oxygen pulse, or the ventilatory equivalent for carbon dioxide in patients with maximal exercise stress testing (n = 73 [58%]). TAPSE is reproducibly measured by echocardiography in patients with TOF. It is not associated with RV ejection fraction or exercise performance, and its association with RV stroke volume may be confounded by body size. On the basis of these results, TAPSE is not representative of global RV performance in patients with TOF. Copyright © 2013 American Society of Echocardiography. Published by Mosby, Inc. All rights reserved.

  8. Right ventricular systolic function in hypertensive heart failure

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    Oketona OA

    2017-09-01

    Full Text Available OA Oketona,1 MO Balogun,2 AO Akintomide,2 OE Ajayi,2 RA Adebayo,2 TO Mene-Afejuku,3 OT Oketona,1 OJ Bamikole2 1Fort Nelson General Hospital, Fort Nelson, BC, Canada; 2Cardiology Unit, Department of Medicine, Obafemi Awolowo University Teaching Hospitals Complex, Ife, Osun State, Nigeria; 3Department of Medicine, Metropolitan Hospital Center, New York, NY, USA Background: Heart failure (HF is a major cause of cardiovascular admissions and hypertensive heart failure (HHF is the most common cause of HF admissions in sub-Saharan Africa, Nigeria inclusive. Right ventricular (RV dysfunction is being increasingly recognized in HF and found to be an independent predictor of adverse outcomes in HF. This study aimed to determine the prevalence of RV systolic dysfunction in HHF by several echocardiographic parameters.Methodology: One hundred subjects with HHF were recruited consecutively into the study along with 50 age and sex-matched controls. All study participants gave written informed consent, and had a full physical examination, blood investigations, 12-lead electrocardiogram, and transthoracic echocardiography. RV systolic function was assessed in all subjects using different methods based on the American Society of Echocardiography guidelines for echocardiographic assessment of the right heart in adults. This included tricuspid annular plane systolic excursion (TAPSE, RV myocardial performance index (MPI, and RV systolic excursion velocity by tissue Doppler (S′.Results: RV systolic dysfunction was found in 53% of subjects with HHF by TAPSE, 56% by RV MPI, and 48% by tissue Doppler systolic excursion S′. RV systolic dysfunction increased with reducing left ventricular ejection fraction (LVEF in subjects with HHF.Conclusion: A high proportion of subjects with HHF were found to have RV systolic functional abnormalities using TAPSE, RV MPI, and RV S′. Prevalence of RV systolic dysfunction increased with reducing LVEF. Keywords: right ventricle

  9. Cruise tourism shore excursions

    DEFF Research Database (Denmark)

    João Lopes, Maria; Dredge, Dianne

    2018-01-01

    Very complex yet highly integrated business logics characterise cruise tourism with shore excursions frequently identified as a key source of value. This paper presents a case study of cruise tourism and shore excursion planning in Copenhagen, Denmark. The aim of this paper is to investigate...... the characteristics of cruise tourism, itinerary and shore excursion planning with a view to understanding the value generated from cruise tourism shore excursions. We argue that economic value is a blunt measure, and there are other types of value, positive and negative, that are also generated. This research...... reveals that a range of local conditions and structural characteristics create barriers and opportunities for generating different types of value. Using a case study of shore excursions in Copenhagen, the Baltic’s most important port, this paper explains the dynamics between cruise tourism and shore...

  10. Cardiac systolic function in cirrhotic patients’ candidate of liver trans-plantation compared with control group

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    Roya Sattarzadeh-Badkoubeh

    2017-02-01

    Full Text Available Background: We assessed different systolic cardiac indices to describe left and right ventricular dysfunction in cirrhotic patients before liver transplantation. Methods: In this case-control study, eighty-one consecutive individuals with the confirmed hepatic cirrhosis and candidate for liver transplantation in the Imam Khomeini Hospital between March 2008 and March 2010 were selected. Thirty-two age and gender cross-matched healthy volunteers were also selected as the control group. A detailed two-dimensional and Doppler echocardiography was obtained in all patients and controls performed by the same operator on the day of admission. Results: Dimensions of both left and right atriums as well as left ventricular end-diastolic volume and basal right ventricular dimension in the cirrhotic group were significantly higher than control group. Left ventricular end-systolic dimensions as well as aortic annulus diameter were not different between the two study groups. Left ventricular outflow tract velocity time integral, isovolumic pre-ejection time, isovolumic relaxation time, stroke volume, left ventricular ejection fraction, IVCT+IVRT+ET, systolic velocity of tricuspid annulus, systolic velocity of basal segment of RV free wall, systolic velocity of basal segment of septal wall, peak strain of septal margin (base, peak strain of septal margin (midpoint, peak strain of lateral margin (midpoint, strain rate of septal margin (base, strain rate of septal margin (midpoint, strain rate of lateral margin (base, strain rate of lateral margin (midpoint, Tei index (left and right ventricles, systolic time interval and tricuspid annular plane systolic excursion were higher in cirrhotic group, significantly, (P< 0.05. Left ventricular ejection time and systolic velocity of mid segment of lateral wall were lower in cirrhotic group, significantly, (P< 0.05. Conclusion: In this study, the effects of liver on heart were volume overload, hyperdynamic state and

  11. Educational role of excursion tourism

    OpenAIRE

    Stanić-Jovanović Sara

    2015-01-01

    Excursion tourism as a mode of travelling to closer destinations has had a long tradition and a cognitive character. Excursions belong to the specific forms of tourism trends and as such, can be viewed in terms of their significant impact on tourist trade within the Serbian tourism market. The demand for this type of tourist travel is constant, thereby highlighting its economic importance. Themed excursions of children in protected areas are developing an interest in nature and are building e...

  12. Excursion Processes Associated with Elliptic Combinatorics

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    Baba, Hiroya; Katori, Makoto

    2018-06-01

    Researching elliptic analogues for equalities and formulas is a new trend in enumerative combinatorics which has followed the previous trend of studying q-analogues. Recently Schlosser proposed a lattice path model in the square lattice with a family of totally elliptic weight-functions including several complex parameters and discussed an elliptic extension of the binomial theorem. In the present paper, we introduce a family of discrete-time excursion processes on Z starting from the origin and returning to the origin in a given time duration 2 T associated with Schlosser's elliptic combinatorics. The processes are inhomogeneous both in space and time and hence expected to provide new models in non-equilibrium statistical mechanics. By numerical calculation we show that the maximum likelihood trajectories on the spatio-temporal plane of the elliptic excursion processes and of their reduced trigonometric versions are not straight lines in general but are nontrivially curved depending on parameters. We analyze asymptotic probability laws in the long-term limit T → ∞ for a simplified trigonometric version of excursion process. Emergence of nontrivial curves of trajectories in a large scale of space and time from the elementary elliptic weight-functions exhibits a new aspect of elliptic combinatorics.

  13. Educational role of excursion tourism

    Directory of Open Access Journals (Sweden)

    Stanić-Jovanović Sara

    2015-01-01

    Full Text Available Excursion tourism as a mode of travelling to closer destinations has had a long tradition and a cognitive character. Excursions belong to the specific forms of tourism trends and as such, can be viewed in terms of their significant impact on tourist trade within the Serbian tourism market. The demand for this type of tourist travel is constant, thereby highlighting its economic importance. Themed excursions of children in protected areas are developing an interest in nature and are building environmental practices. Thus, children are introduced to the ways of environmental protection, fostering a positive attitude towards the values of preserved natural environment as an opportunity to raise environmental awareness of future generations.

  14. Quaternary magnetic excursions recorded in marine sediments.

    Science.gov (United States)

    Channell, J. E. T.

    2017-12-01

    This year is the golden (50th) anniversary of the first documentation of a magnetic excursion, the Laschamp excursion in volcanics from the Chaine des Puys (Bonhommet and Babkine, 1967). The first recording of an excursion in sediments was from the Blake Outer Ridge (Smith and Foster, 1969). Magnetic excursions are directional aberrations of the geomagnetic field apparently involving short-lived reversal of the main dipole field. They have durations of a few kyrs, and are therefore rarely recorded in sediments with mean sedimentation rates Palma), and 670 ka (Osaka Bay), implying at least 11 excursions in the Brunhes Chron. For the Matuyama Chron, excursions have been recorded in marine sediments at 868 ka (Kamikatsura?), 932 ka (Santa Rosa), 1051 ka (Intra-Jaramillo), 1115 ka (Punaruu), 1255 ka (Bjorn), 1476 ka (Gardar), 1580 ka (Gilsa), and 2737 ka (Porcupine). Excursions coincide with minima in relative paleointensity (RPI) records. Ages are from correlation of excursion records to oxygen isotope records in the same cores, and ice-volume calibration of the oxygen isotope template. The marine sediment record of excursions, combined with independent documentation of excursions in lavas with Ar/Ar age control, is progressively strengthening our knowledge of the excursion inventory in the Quaternary, and enhancing the importance of excursions and RPI in Quaternary stratigraphy.

  15. Additive functionals and excursions of Kuznetsov processes

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    Hacène Boutabia

    2005-01-01

    semigroup of transition. In this paper, we give the excursion laws of (Xtt∈ℝ+ conditioned on the strict past and future without duality hypothesis. We study excursions of a general regenerative system and of a regenerative system consisting of the closure of the set of times the regular points of B are visited. In both cases, those conditioned excursion laws depend only on two points Xg− and Xd, where ]g,d[ is an excursion interval of the regenerative set M. We use the (FDt-predictable exit system to bring together the isolated points of M and its perfect part and replace the classical optional exit system. This has been a subject in literature before (e.g., Kaspi (1988 under the classical duality hypothesis. We define an “additive functional” for (Ytt∈ℝ with B, we generalize the laws cited before to (Ytt∈ℝ, and we express laws of pairs of excursions.

  16. On excursion increments in heartbeat dynamics

    International Nuclear Information System (INIS)

    Guzmán-Vargas, L.; Reyes-Ramírez, I.; Hernández-Pérez, R.

    2013-01-01

    We study correlation properties of excursion increments of heartbeat time series from healthy subjects and heart failure patients. We construct the excursion time based on the original heartbeat time series, representing the time employed by the walker to return to the local mean value. Next, the detrended fluctuation analysis and the fractal dimension method are applied to the magnitude and sign of the increments in the time excursions between successive excursions for the mentioned groups. Our results show that for magnitude series of excursion increments both groups display long-range correlations with similar correlation exponents, indicating that large (small) increments (decrements) are more likely to be followed by large (small) increments (decrements). For sign sequences and for both groups, we find that increments are short-range anti-correlated, which is noticeable under heart failure conditions

  17. Power excursion models applied to the study of secundary excursion in sodium cooled fast breeder reactors

    International Nuclear Information System (INIS)

    Messainguiral, Christiane.

    1980-06-01

    An evaluation of the energy that a secondary power excursion could release has been sought throughout the present work. A parametric study was therefore made by means of a power excursion code in fast reactors. The work submitted is therefore made up of the three following parts: Part 1. - (a), the secondary excursion is situated in the generally envisaged programmes and (b) the role of the principal parameters is studied in the calculation effected by the nuclear excursion code that was available at the start of the study. Part 2. - the results obtained for the power excursion calculations made are presented, Part 3. - the insufficient modelling of the reactivity present during the secondary power excursion is deduced from the parametric study just made. A definition is made of the characteristics of a model adapted to the calculation of this hypothetical accident and a new model as worked out within the scope of this work is submitted [fr

  18. Hyperbolic isometries of systolic complexes

    DEFF Research Database (Denmark)

    Prytula, Tomasz Pawel

    The main topics of this thesis are the geometric features of systolic complexesarising from the actions of hyperbolic isometries. The thesis consists ofan introduction followed by two articles.Given a hyperbolic isometry h of a systolic complex X, our central theme isto study the minimal displace......The main topics of this thesis are the geometric features of systolic complexesarising from the actions of hyperbolic isometries. The thesis consists ofan introduction followed by two articles.Given a hyperbolic isometry h of a systolic complex X, our central theme isto study the minimal...... algebraic-topological features of systolic groups. In addition, we provide newexamples of systolic groups.In the first article we show that the minimal displacement set of a hyperbolicisometry of a systolic complex is quasi-isometric to the product of a tree andthe real line. We use this theorem...

  19. Geomagnetic field evolution during the Laschamp excursion

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    Leonhardt, Roman; Fabian, Karl; Winklhofer, Michael; Ferk, Annika; Laj, Carlo; Kissel, Catherine

    2009-02-01

    Since the last geomagnetic reversal, 780,000 years ago, the Earth's magnetic field repeatedly dropped dramatically in intensity. This has often been associated with large variations in local field direction, but without a persistent global polarity flip. The structure and dynamics of geomagnetic excursions, and especially the difference between excursions and polarity reversals, have remained elusive so far. For the best documented excursion, the Laschamp event at 41,000 years BP, we have reconstructed the evolution of the global field morphology by using a Bayesian inversion of several high-resolution palaeomagnetic records. We have obtained an excursion scenario in which inverse magnetic flux patches at the core-mantle boundary emerge near the equator and then move poleward. Contrary to the situation during the last reversal (Leonhardt, R., Fabian, K., 2007. Paleomagnetic reconstruction of the global geomagnetic field evolution during the Matuyama/Brunhes transition: Iterative Bayesian inversion and independent verification. Earth Planet. Sci. Lett. 253, 172-195), these flux patches do not cross the hydrodynamic boundary of the inner-core tangent cylinder. While the last geomagnetic reversal began with a substantial increase in the strength of the non-dipolar field components, prior to the Laschamp excursion, both dipolar and non-dipolar field decay at the same rate. This result suggests that the nature of an upcoming geomagnetic field instability can be predicted several hundred years in advance. Even though during the Laschamp excursion the dipolar field at the Earth's surface was dominant, the reconstructed dynamic non-dipolar components lead to considerable deviations among predicted records at different locations. The inverse model also explains why at some locations no directional change during the Laschamp excursion is observed.

  20. Isolated Systolic Hypertension: A Health Concern?

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    Isolated systolic hypertension: A health concern? Is having a high top number (systolic) blood pressure, but a normal bottom number (diastolic) ... mm Hg, you have a common type of high blood pressure called isolated systolic hypertension. Isolated systolic hypertension can ...

  1. Systolic ventricular filling.

    Science.gov (United States)

    Torrent-Guasp, Francisco; Kocica, Mladen J; Corno, Antonio; Komeda, Masashi; Cox, James; Flotats, A; Ballester-Rodes, Manel; Carreras-Costa, Francesc

    2004-03-01

    The evidence of the ventricular myocardial band (VMB) has revealed unavoidable coherence and mutual coupling of form and function in the ventricular myocardium, making it possible to understand the principles governing electrical, mechanical and energetical events within the human heart. From the earliest Erasistratus' observations, principal mechanisms responsible for the ventricular filling have still remained obscured. Contemporary experimental and clinical investigations unequivocally support the attitude that only powerful suction force, developed by the normal ventricles, would be able to produce an efficient filling of the ventricular cavities. The true origin and the precise time frame for generating such force are still controversial. Elastic recoil and muscular contraction were the most commonly mentioned, but yet, still not clearly explained mechanisms involved in the ventricular suction. Classical concepts about timing of successive mechanical events during the cardiac cycle, also do not offer understandable insight into the mechanism of the ventricular filling. The net result is the current state of insufficient knowledge of systolic and particularly diastolic function of normal and diseased heart. Here we summarize experimental evidence and theoretical backgrounds, which could be useful in understanding the phenomenon of the ventricular filling. Anatomy of the VMB, and recent proofs for its segmental electrical and mechanical activation, undoubtedly indicates that ventricular filling is the consequence of an active muscular contraction. Contraction of the ascendent segment of the VMB, with simultaneous shortening and rectifying of its fibers, produces the paradoxical increase of the ventricular volume and lengthening of its long axis. Specific spatial arrangement of the ascendent segment fibers, their interaction with adjacent descendent segment fibers, elastic elements and intra-cavitary blood volume (hemoskeleton), explain the physical principles

  2. Random-process excursions in radioisotope instruments

    International Nuclear Information System (INIS)

    Galochkin, D.V.; Polovko, S.A.

    1984-01-01

    Approximate expressions are derived for the mathematical expectation, variance, and distribution of the durations of the excursions of the output signal from a ratemeter in a radioisotope relay instrument. The tabulated comparison of results from Monte Carlo simulation and analytical calculation shows good agreement over the mean value and the variance of the excursion duration for T 0.2 sec as calculated and as obtained by Monte Carlo simulation with a computer using 5000 realizations. It is suggested that the results should be used in choosing the optimum parameters of radioisotope relay instruments

  3. Clericalization of the Russian Excursion Tourism

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    Boris Rodoman

    2014-05-01

    Full Text Available In the modern Russia almost every secular excursion is starting to resemble a religious pilgrimage, while reducing itself to a visit to Orthodox monasteries and temples. A lot of stories are told about saints and their actions, an unconcealed religious propaganda is carried on, and the history of the country is presented in a cleric-monarchical manner.

  4. International excursion hydrogeology, Slovakia, [September 8 - 15, 1996

    NARCIS (Netherlands)

    Dijksma, R.

    1996-01-01

    This is a report of the hydrogeological excursion to Slovakia, held in the period from September 8 up to September 15, 1996. This report is a compilation of the work of the participating students, parts of the excursion guide and also information, provided by the Slovak excursion guides.

  5. Bounded excursion stable gravastars and black holes

    Energy Technology Data Exchange (ETDEWEB)

    Rocha, P [Instituto de Fisica, Universidade Federal Fluminense, Avenida Litoranea, s/n, Boa Viagem 24210-340, Niteroi, RJ (Brazil); Miguelote, A Y; Chan, R [Coordenacao de Astronomia e Astrofisica, Observatorio Nacional, Rua General Jose Cristino, 77, Sao Cristovao 20921-400, Rio de Janeiro, RJ (Brazil); Da Silva, M F; Wang, Anzhong [Departamento de Fisica Teorica, Instituto de Fisica, Universidade do Estado do Rio de Janeiro, Rua Sao Francisco Xavier 524, Maracana 20550-900, Rio de Janeiro-RJ (Brazil); Santos, N O, E-mail: pedrosennarocha@gmail.com, E-mail: yasuda@on.br, E-mail: chan@on.br, E-mail: mfasnic@gmail.com, E-mail: N.O.Santos@qmul.ac.uk, E-mail: anzhong_wang@baylor.edu [LERMA/CNRS-FRE 2460, Universite Pierre et Marie Curie, ERGA, Boite 142, 4 Place Jussieu, 75005 Paris Cedex 05 (France)

    2008-06-15

    Dynamical models of prototype gravastars were constructed in order to study their stability. The models are the Visser-Wiltshire three-layer gravastars, in which an infinitely thin spherical shell of stiff fluid divides the whole spacetime into two regions, where the internal region is de Sitter, and the external one is Schwarzschild. It is found that in some cases the models represent the 'bounded excursion' stable gravastars, where the thin shell is oscillating between two finite radii, while in other cases they collapse until the formation of black holes occurs. In the phase space, the region for the 'bounded excursion' gravastars is very small in comparison to that of black holes, but not empty. Therefore, although the possibility of the existence of gravastars cannot be excluded from such dynamical models, our results indicate that, even if gravastars do indeed exist, that does not exclude the possibility of the existence of black holes.

  6. ORNITHOLOGICAL EXCURSIONS IN MURMANSK: GEOINFORMATION ASPECT

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    M. N. Kharlamova

    2014-01-01

    Full Text Available The method to use efficiently GIS-technologies in arranging the field practice of students on ornithology has been proposed. The ornithological excursions were performed in surroundings of the City of Murmansk in the conditions of weakly urbanized landscape. Using the facilities of freely distributed cartographic «SAS-Planet» software a simple GIS was formed in its environment where to the data on bird nest location with their description, the information about the route nodal points, water body crossing, stay places and others were put down. The mentioned data were obtained as a result of preliminary field research with the aid of satellite navigator including accumulating and summing up the information for a number of previous similar investigations. As a result, a final route in the current year was developed using which during the field practice the ornithological excursions were arranged.

  7. Nearaffine planes

    NARCIS (Netherlands)

    Wilbrink, H.A.

    1982-01-01

    In this paper we develop a theory for nearaffine planes analogous to the theory of ordinary affine translation planes. In a subsequent paper we shall use this theory to give a characterization of a certain class of Minkowski planes.

  8. Educational Excursions in Technical Schools of Pre-revolutionary Russia

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    Timur A. Magsumov

    2013-01-01

    Full Text Available The author, using the data of pre-revolutionary technical schools, traces the genesis and trends of educational excursions development in the Russian Empire. Special attention is attached to the types, organizational forms and methods of excursion activities, educational policy, concerning its development. The article presents author’s classification of educational excursions, notes that educational excursions have become traditional and were operated systematically by the early XX century. Field excursions, which in fact displaced introductive training, prevailed in technical schools

  9. Systolic trees and systolic language recognition by tree automata

    Energy Technology Data Exchange (ETDEWEB)

    Steinby, M

    1983-01-01

    K. Culik II, J. Gruska, A. Salomaa and D. Wood have studied the language recognition capabilities of certain types of systolically operating networks of processors (see research reports Cs-81-32, Cs-81-36 and Cs-82-01, Univ. of Waterloo, Ontario, Canada). In this paper, their model for systolic VLSI trees is formalised in terms of standard tree automaton theory, and the way in which some known facts about recognisable forests and tree transductions can be applied in VLSI tree theory is demonstrated. 13 references.

  10. Accuracy and interobserver concordance of echocardiographic assessment of right ventricular size and systolic function: a quality control exercise.

    Science.gov (United States)

    Ling, Lee Fong; Obuchowski, Nancy A; Rodriguez, Leonardo; Popovic, Zoran; Kwon, Deborah; Marwick, Thomas H

    2012-07-01

    Accurate assessment of right ventricular (RV) size (RVS) and RV systolic function (RVSF) is vital in the management of various conditions, but their assessment is challenging using echocardiography. The aim of this study was to determine the accuracy and interobserver concordance of qualitative and quantitative RV echocardiography. Fifteen readers evaluated RV function in 12 patients (360 readings) who underwent echocardiography and cardiac magnetic resonance for RV assessment. Readers qualitatively estimated RVS and RVSF as normal, mild, moderate, or severe and then reassessed quantitatively by adding RV dimensions, fractional area change, S', tricuspid annular plane systolic excursion, and RV index of myocardial performance. Cardiac magnetic resonance was used as the reference standard for grading RVS and RVSF. Quantitative measurements increased accuracy and interreader agreement compared to qualitative assessment alone, especially in normal categories. Readers' accuracy for diagnosing normal and severe RVS increased from 38% to 78% (P = .001) and from 70% to 97% (P = .018), and readers' accuracy for diagnosing normal and mild RVSF increased from 52% to 84% (P value of 0.40 to 0.77 (fair to good agreement) for RVS and from 0.43 to 0.66 (moderate to good agreement) for RVSF. Visual estimation of RVS and RVSF is inaccurate and has wide interobserver variability. Quantitation improves accuracy and reliability, especially in distinction of normal and abnormal. The reliability of mild and moderate grades remains inadequate, and further guidance is needed for the classification of abnormal categories. Copyright © 2012 American Society of Echocardiography. Published by Mosby, Inc. All rights reserved.

  11. Virtual reality excursions with programs in C

    CERN Document Server

    Watkins, Christopher D

    1994-01-01

    Virtual Reality Excursions with Programs in C provides the history, theory, principles and an account of the milestones in the development of virtual reality technology.The book is organized into five chapters. The first chapter explores the applications in the vast field of virtual reality. The second chapter presents a brief history of the field and its founders. Chapter 3 discusses human perception and how it works. Some interesting notes and much of the hot debate in the field are covered in Chapter 4. The fifth chapter describes many of the complexities involved in implementing virtual en

  12. Hyper-systolic matrix multiplication

    NARCIS (Netherlands)

    Lippert, Th.; Petkov, N.; Palazzari, P.; Schilling, K.

    A novel parallel algorithm for matrix multiplication is presented. It is based on a 1-D hyper-systolic processor abstraction. The procedure can be implemented on all types of parallel systems. (C) 2001 Elsevier Science B,V. All rights reserved.

  13. Simulation of power excursions - Osiris reactor; Simulation des excursions de puissance - pile Osiris

    Energy Technology Data Exchange (ETDEWEB)

    Pascouet, A [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1964-07-01

    Following the experimental work accomplished in the U.S.A. on Borax 1 and SPERT 1 and the accident of SL 1, the 'Commissariat a l'Energie Atomique' started a research program about the safety of its own swimming Pool reactors, with regard to power excursions. The first research work led to the design of programmed explosive charges, adapted to the simulation of a power excursion. This report describes the application of these methods to the investigation of Osiris safety. (author) [French] A la suite des essais effectues aux U.S.A. sur BORAX 1 et SPERT 1 et de l'accident survenu a SL 1, le Commissariat a l'Energie Atomique a lance un programme d'etudes sur la surete de ses reacteurs piscines vis-a-vis des excursions de puissance. Les premieres etudes ont abouti A la mise au point de charges programmees capables de simuler une excursion de puissance. On trouvera dans le present rapport l'application de ces methodes a l'etude de la surete d'OSIRIS. (auteur)

  14. Regional differences in prognostic value of cardiac valve plane displacement in systemic light-chain amyloidosis.

    Science.gov (United States)

    Ochs, Marco M; Fritz, Thomas; Arenja, Nisha; Riffel, Johannes; Andre, Florian; Mereles, Derliz; Siepen, Fabian Aus dem; Hegenbart, Ute; Schönland, Stefan; Katus, Hugo A; Friedrich, Matthias G W; Buss, Sebastian J

    2017-11-09

    To compare the prognostic value of cardiac valve plane displacement (CVPD) on various locations in cardiac light chain (AL) amyloidosis. Consecutive patients with biopsy-proven cardiac involvement in AL amyloidosis who had undergone cardiovascular magnetic resonance (CMR) between 2005 and 2014 in our institution, were retrospectively identified and data analyzed. The primary combined endpoint was all-cause mortality or heart transplantation. Systolic CVPD were obtained from standard cine bSSFP in 2-, 3- and 4-chamber views at anterior aortic plane systolic excursion (AAPSE); anterior, anterolateral, inferolateral, inferior, inferoseptal mitral (MAPSE); and lateral tricuspid (TAPSE) annular segments. We identified 68 patients (58 ± 10 years; 59% male). Median follow-up period was 1.2 years (IQR, 0.3-4.1). Significant differences in CVPD between patients who reached a primary endpoint (n = 44) and transplant-free survivors were found only for AAPSE (6.1 mm (IQR, 4.6-9.4) vs. 8.8 mm (IQR, 6.9-10.4); p = 0.02) and MAPSE anterolateral (7.3 mm (IQR, 5.4-11.7) vs. 10.5 mm (IQR, 8.1-13.4); p = 0.03). AAPSE (χ 2  = 15.6; p = 0.0002) provided the best predictive value for transplant-free survival compared to all other valvular plane locations. A high-risk cutoff (AAPSE ≤ 7.6 mm) was calculated by ROC analysis to predict all-cause death or heart transplantation within 6 months from index examination (AUC = 0.80; CI: 0.68 to 0.89; p model of late gadolinium enhancement and global longitudinal strain (GLS) (∆χ 2  = 5.8, p = 0.02) as well as to a clinical model including Karnofsky index and NT-proBNP (∆χ 2  = 6.2, p = 0.01). In patients with cardiac involvement in AL amyloidosis, systolic CVPD obtained from standard long axis cine views appear to indicate outcome better, when obtained in the anterior aortic plane (AAPSE) and provide incremental prognostic value to LGE and strain measurements.

  15. Mass functions from the excursion set model

    Science.gov (United States)

    Hiotelis, Nicos; Del Popolo, Antonino

    2017-11-01

    Aims: We aim to study the stochastic evolution of the smoothed overdensity δ at scale S of the form δ(S) = ∫0S K(S,u)dW(u), where K is a kernel and dW is the usual Wiener process. Methods: For a Gaussian density field, smoothed by the top-hat filter, in real space, we used a simple kernel that gives the correct correlation between scales. A Monte Carlo procedure was used to construct random walks and to calculate first crossing distributions and consequently mass functions for a constant barrier. Results: We show that the evolution considered here improves the agreement with the results of N-body simulations relative to analytical approximations which have been proposed from the same problem by other authors. In fact, we show that an evolution which is fully consistent with the ideas of the excursion set model, describes accurately the mass function of dark matter haloes for values of ν ≤ 1 and underestimates the number of larger haloes. Finally, we show that a constant threshold of collapse, lower than it is usually used, it is able to produce a mass function which approximates the results of N-body simulations for a variety of redshifts and for a wide range of masses. Conclusions: A mass function in good agreement with N-body simulations can be obtained analytically using a lower than usual constant collapse threshold.

  16. Axion excursions of the landscape during inflation

    Science.gov (United States)

    Palma, Gonzalo A.; Riquelme, Walter

    2017-07-01

    Because of their quantum fluctuations, axion fields had a chance to experience field excursions traversing many minima of their potentials during inflation. We study this situation by analyzing the dynamics of an axion field ψ , present during inflation, with a periodic potential given by v (ψ )=Λ4[1 -cos (ψ /f )]. By assuming that the vacuum expectation value of the field is stabilized at one of its minima, say, ψ =0 , we compute every n -point correlation function of ψ up to first order in Λ4 using the in-in formalism. This computation allows us to identify the distribution function describing the probability of measuring ψ at a particular amplitude during inflation. Because ψ is able to tunnel between the barriers of the potential, we find that the probability distribution function consists of a non-Gaussian multimodal distribution such that the probability of measuring ψ at a minimum of v (ψ ) different from ψ =0 increases with time. As a result, at the end of inflation, different patches of the Universe are characterized by different values of the axion field amplitude, leading to important cosmological phenomenology: (a) Isocurvature fluctuations induced by the axion at the end of inflation could be highly non-Gaussian. (b) If the axion defines the strength of standard model couplings, then one is led to a concrete realization of the multiverse. (c) If the axion corresponds to dark matter, one is led to the possibility that, within our observable Universe, dark matter started with a nontrivial initial condition, implying novel signatures for future surveys.

  17. Flow-excursion-induced dryout at low-heat-flux

    International Nuclear Information System (INIS)

    Khatib-Rahbar, M.; Cazzoli, E.G.

    1983-01-01

    Flow-excursion-induced dryout at low-heat-flux natural-convection boiling, typical of liquid-metal fast-breeder reactors, is addressed. Steady-state calculations indicate that low-quality boiling is possible up to the point of Ledinegg instability leading to flow excursion and subsequent dryout in agreement with experimental data. A flow-regime-dependent dryout heat flux relationship based upon saturated boiling criterion is also presented. Transient analysis indicates that premature flow excursion can not be ruled out and sodium boiling is highly transient dependent. Analysis of a high-heat-flux forced convection, loss-of-flow transient shows a significantly faster flow excursion leading to dryout in excellent agreement with parallel calculations using the two-dimensional THORAX code. 17 figures

  18. HMSRP Hawaiian Monk Seal Shark Predation Mitigation Fishing Excursions

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Fishing excursion information, including summary tables of: Fishing/culling efforts, including date, islets, latitude/longitude, fishing method, soak times, culled...

  19. Towards a global view of the Laschamp excursion

    Science.gov (United States)

    Laj, C.; Kissel, C.; Leonhardt, R.; Fabian, K.; Winklhofer, M.; Ferk, A.; Ninnemann, U.

    2009-04-01

    A new record of a geomagnetic excursion has been obtained from Core MD07-3128 taken at (75° 34' W ; 52° 40' S) off the Pacific coast of Southern Chile, during the IMAGES XV-MD159-PACHIDERME cruise of the R/V Marion Dufresne (IPEV). Radiocarbon datings extend for the moment to 36.3 kyr BP at 18 meters. Linear extrapolation of the last 2 dates downcore, gives an age of 40.7 for the middle point of the excursion at 20.5 m. This age is virtually identical to the most precise and reliable dating of the Laschamp excursion (obtained by K/Ar and 40Ar/39Ar) at the type locality at Laschamp, where Norbert Bonhommet first discovered the excursion during his PhD research work. We therefore consider that we have obtained a new record of the Laschamp Excursion. Because of the extraordinarily high sediment accumulation rate, the directional excursion is recorded over about 2 meters of sediment (between 19,65 and 21,5) and corresponds to a prolonged marked low in the relative paleointensity record. Details of the directional and relative paleointensity changes will be discussed. The high southern latitude at which this new record was obtained and its very detailed nature make it ideal to further constrain the inverse model of the Laschamp Excursion (IMOLEe) (Leonhardt et al. EPSL in press). The results obtained when these new data are considered in the model will be discussed in terms of dipolar versus non-dipolar components of the transistional field and comparison between predicted (modeled) and observed directions at all the sites used for the construction of this last version of the inverse model (IMOLEf).

  20. Disk Disruptions and X-ray Intensity Excursions in Cyg X-2, LMC X-3 and Cyg X-3

    Science.gov (United States)

    Boyd, P. T.; Smale, A. P.

    2001-05-01

    The RXTE All Sky Monitor soft X-ray light curves of many X-ray binaries show long-term intensity variations (a.k.a "superorbital periodicities") that have been ascribed to precession of a warped, tilted accretion disk around the X-ray source. We have found that the excursion times between X-ray minima in Cyg X-2 can be characterized as a series of integer multiples of the 9.8 binary orbital period, (as opposed to the previously reported stable 77.7 day single periodicity, or a single modulation whose period changes slowly with time). While the data set is too short for a proper statistical analysis, it is clear that the length of any given intensity excursion cannot be used to predict the next (integer) excursion length in the series. In the black hole candidate system LMC X-3, the excursion times are shown to be related to each other by rational fractions. We find that the long term light curve of the unusual galactic X-ray jet source Cyg X-3 can also be described as a series of intensity excursions related to each other by integer multiples of a fundamental underlying clock. In the latter cases, the clock is apparently not related to the known binary periods. A unified physical model, involving both an inclined accretion disk and a fixed-probability disk disruption mechanism is presented, and compared with three-body scattering results. Each time the disk passes through the orbital plane it experiences a fixed probability P that it will disrupt. This model has testable predictions---the distribution of integers should resemble that of an atomic process with a characteristic half life. Further analysis can support or refute the model, and shed light on what system parameters effectively set the value of P.

  1. Buoyancy-driven flow excursions in fuel assemblies

    International Nuclear Information System (INIS)

    Laurinat, J.E.; Paul, P.K.; Menna, J.D.

    1995-01-01

    A power limit criterion was developed for a postulated Loss of Pumping Accident (LOPA) in one of the recently shut down heavy water production reactors at the Savannah River Site. These reactors were cooled by recirculating heavy water moderator downward through channels in cylindrical fuel tubes. Powers were limited to safeguard against a flow excursion in one of more of these parallel channels. During-full-power operation, limits safeguarded against a boiling flow excursion. At low flow rates, during the addition of emergency cooling water, buoyant forces reverse the flow in one of the coolant channels before boiling occurs. As power increased beyond the point of flow reversal, the maximum wall temperature approaches the fluid saturation temperature, and a thermal excursion occurs. The power limit criterion for low flow rates was the onset of flow reversal. To determine conditions for flow reversal, tests were performed in a mock-up of a fuel assembly that contained two electrically heated concentric tubes surrounded by three flow channels. These tests were modeled using a finite difference thermal-hydraulic code. According to code calculations, flow reversed in the outer flow channel before the maximum wall temperature reached the local fluid saturation temperature. Thermal excursions occurred when the maximum wall temperature approximately equaled the saturation temperature. For a postulated LOPA, the flow reversal criterion for emergency cooling water addition was more limiting than the boiling excursion criterion for full power operation. This criterion limited powers to 37% of the limiting power for previous long-term reactor operations

  2. Diaphragmatic excursion: does it predict successful weaning from mechanical ventilation?

    International Nuclear Information System (INIS)

    Hayat, A.; Khalil, A.

    2017-01-01

    To measure the diaphragmatic excursion and its outcome on weani ng from mechanical ventilation. Study Design: Cross-sectional comparative study. Place and Duration of Study: Medical Intensive Care Unit (ICU), Military Hospital (MH), Rawalpindi, Pakistan, from January to December 2014. Methodology: Diaphragmatic excursion (DE) in cm was measured through ultrasound by marking liver and spleen displacement in patients who fulfilled the criteria of removal from ventilatory support. The patients were followed up for 48 hours and classified according to the outcome as successful weaning and weaning failure. Results: Out of 100 cases, 76 patients had a successful weaning while 24 had a failed weaning outcome. At a diaphragmatic excursion of 1.2 cm and more, out of 67 cases, 60 had a successful weaning (89.55%) while 7 cases (10.45%) had a weaning failure. At an excursion of less than 1. 2 cm, 17 out of 33 cases (51.5%) had successful weaning while 16 (48.48%) had weaning failure. At this cut off point (1.2 cm), the sensitivity and specificity for successful weaning were 78.95% and 70.83%, respectively. The positive and negative likelihood ratio (LR) for these values being 2.70 and 0.29, respectively. The positive predictive value was 82.35% and negative predictive value 60.00%. Conclusion: Ultrasonographic measurement of diaphragmatic excursion is a good method for predicting weaning outcome from mechanical ventilation. (author)

  3. K-Ar ages of the Auckland geomagnetic excursions

    International Nuclear Information System (INIS)

    Mochizuki, Nobutatsu; Tsunakawa, Hideo; Shibuya, Hidetoshi; Tagami, Takahiro; Ozawa, Ayako; Cassidy, John; Smith, E.M.

    2004-01-01

    K-Ar age determinations were made on two monogenetic volcanoes in the Auckland volcanic field, New Zealand, which have recorded the Auckland geomagnetic excursions. For the Wiri volcano with the north-down intermediate paleomagnetic direction, five samples gave a weighted mean age of 27±5 (1σ) ka. For the Hampton Park volcano with the west-up intermediate direction, three samples gave a weighted mean of 55±5(1σ) ka. Since these two K-Ar ages are distinguished at 2σ level, it is inferred that at least two geomagnetic excursions can be recognized in Auckland. The age of the Hampton Park is barely distinguished from the established age range of the Laschamp excursion (39-45 ka) at 2σ level. The age of the Wiri coincides with the age of c. 30 ka in which excursions have been found from sedimentary and volcanic records. The reported excursions from volcanic rocks show a VGP cluster in the central to northern Pacific region which is distinct from the VGP paths or clusters during polarity reversals. (author)

  4. Buoyancy-driven flow excursions in fuel assemblies

    Energy Technology Data Exchange (ETDEWEB)

    Laurinat, J.E.; Paul, P.K.; Menna, J.D. [Westinghouse Savannah River Company, Aiken, SC (United States)

    1995-09-01

    A power limit criterion was developed for a postulated Loss of Pumping Accident (LOPA) in one of the recently shut down heavy water production reactors at the Savannah River Site. These reactors were cooled by recirculating heavy water moderator downward through channels in cylindrical fuel tubes. Powers were limited to safeguard against a flow excursion in one of more of these parallel channels. During-full-power operation, limits safeguarded against a boiling flow excursion. At low flow rates, during the addition of emergency cooling water, buoyant forces reverse the flow in one of the coolant channels before boiling occurs. As power increased beyond the point of flow reversal, the maximum wall temperature approaches the fluid saturation temperature, and a thermal excursion occurs. The power limit criterion for low flow rates was the onset of flow reversal. To determine conditions for flow reversal, tests were performed in a mock-up of a fuel assembly that contained two electrically heated concentric tubes surrounded by three flow channels. These tests were modeled using a finite difference thermal-hydraulic code. According to code calculations, flow reversed in the outer flow channel before the maximum wall temperature reached the local fluid saturation temperature. Thermal excursions occurred when the maximum wall temperature approximately equaled the saturation temperature. For a postulated LOPA, the flow reversal criterion for emergency cooling water addition was more limiting than the boiling excursion criterion for full power operation. This criterion limited powers to 37% of the limiting power for previous long-term reactor operations.

  5. Buoyancy-driven flow excursions in fuel assemblies

    International Nuclear Information System (INIS)

    Laurinat, J.E.; Paul, P.K.; Menna, J.D.

    1995-01-01

    A power limit criterion was developed for a postulated Loss of Pumping Accident (LOPA) in one of the recently shut down heavy water production reactors at the Savannah River Site. These reactors were cooled by recirculating moderator downward through channels in cylindrical fuel tubes. Powers were limited to prevent a flow excursion from occurring in one or more of these parallel channels. During full-power operation, limits prevented a boiling flow excursion from taking place. At low flow rates, during the addition of emergency cooling water, buoyant forces reverse the flow in one of the coolant channels before boiling occurs. As power increases beyond the point of flow reversal, the maximum wall temperature approaches the fluid saturation temperature, and a thermal excursion occurs. The power limit criterion for low flow rates was the onset of flow reversal. To determine conditions for flow reversal, tests were performed in a mock-up of a fuel assembly that contained two electrically heated concentric tubes surrounded by three flow channels. These tests were modeled using a finite difference thermal-hydraulic code. According to code calculations, flow reversed in the outer flow channel before the maximum wall temperature reached the local fluid saturation temperature. Thermal excursions occurred when the maximum wall temperature approximately equaled the saturation temperature. For a postulated LOPA, the flow reversal criterion for emergency cooling water addition was more limiting than the boiling excursion criterion for full power operation. This criterion limited powers to 37% of historical levels

  6. Oskarshamn site investigation. Bedrock geology - overview and excursion guide

    Energy Technology Data Exchange (ETDEWEB)

    Wahlgren, Carl-Henric (Geological Survey of Sweden, Uppsala (Sweden))

    2010-09-15

    Bearing in mind the significance of the bedrock data from the ground surface for the geological 3D modelling work, SKB decided to present excursion guides that serve in the demonstration of the bedrock geology at the ground surface in both the Forsmark and Laxemar-Simpevarp (this guide) areas. An excursion guide is also available for the Olkiluoto area in south-western Finland, which has been selected for the construction of a repository for the disposal of highly radioactive, spent nuclear fuel. The current excursion guide presents the bedrock geology and describes in detail the character of the bedrock at eight representative outcrops or outcrop areas at the ground surface in the site investigation area at Laxemar-Simpevarp and at one locality north of this area, i.e. at a total of nine localities

  7. Forsmark site investigation. Bedrock geology - overview and excursion guide

    Energy Technology Data Exchange (ETDEWEB)

    Stephens, Michael B. (Geological Survey of Sweden, Uppsala (Sweden))

    2010-09-15

    Bearing in mind the significance of the bedrock data from the ground surface for the geological 3D modelling work, SKB decided to present excursion guides that serve in the demonstration of the bedrock geology at the ground surface in both the Forsmark (this guide) and Laxemar-Simpevarp areas. An excursion guide is also available for the Olkiluoto area in south-western Finland, which has been selected for the construction of a repository for the disposal of highly radioactive, spent nuclear fuel in Finland. The current excursion guide presents the bedrock geology and describes in detail the character of the bedrock at ten representative outcrops or outcrop areas at the ground surface in the site investigation area at Forsmark. All localities are located within or immediately adjacent to the proposed repository volume selected by SKB

  8. Forsmark site investigation. Bedrock geology - overview and excursion guide

    International Nuclear Information System (INIS)

    Stephens, Michael B.

    2010-09-01

    Bearing in mind the significance of the bedrock data from the ground surface for the geological 3D modelling work, SKB decided to present excursion guides that serve in the demonstration of the bedrock geology at the ground surface in both the Forsmark (this guide) and Laxemar-Simpevarp areas. An excursion guide is also available for the Olkiluoto area in south-western Finland, which has been selected for the construction of a repository for the disposal of highly radioactive, spent nuclear fuel in Finland. The current excursion guide presents the bedrock geology and describes in detail the character of the bedrock at ten representative outcrops or outcrop areas at the ground surface in the site investigation area at Forsmark. All localities are located within or immediately adjacent to the proposed repository volume selected by SKB

  9. Oskarshamn site investigation. Bedrock geology - overview and excursion guide

    International Nuclear Information System (INIS)

    Wahlgren, Carl-Henric

    2010-09-01

    Bearing in mind the significance of the bedrock data from the ground surface for the geological 3D modelling work, SKB decided to present excursion guides that serve in the demonstration of the bedrock geology at the ground surface in both the Forsmark and Laxemar-Simpevarp (this guide) areas. An excursion guide is also available for the Olkiluoto area in south-western Finland, which has been selected for the construction of a repository for the disposal of highly radioactive, spent nuclear fuel. The current excursion guide presents the bedrock geology and describes in detail the character of the bedrock at eight representative outcrops or outcrop areas at the ground surface in the site investigation area at Laxemar-Simpevarp and at one locality north of this area, i.e. at a total of nine localities

  10. Systolic hypertension in adult nigerians with hypertension

    International Nuclear Information System (INIS)

    Opadijo, O.G.; Salami, T.A.T.; Sanya, E.O.; Omotoso, A.B.O.

    2007-01-01

    To determine the prevalence of both systolic and diastolic hypertensions in relation to age and their impacts on target organ among adult Nigerians with hypertension. Newly diagnosed adult hypertensives, with blood pressure 140/90mm Hg, taken twice with mercury column sphygmomanometer at 3 weeks interval, were studied. The total number of hypertensive patients treated over this period was also taken into consideration. The newly diagnosed hypertensives were classified using JNC VI classification. The frequency of occurrence of target organ damage such as Left Ventricular Hypertrophy (LVH), heart failure, renal impairment etc. was charted according to systolic and or diastolic pressures. The occurrence of systolic or diastolic blood pressure was also related with the age of the patients. Blood metabolic parameters were compared in both systolic and diastolic blood pressures for their possible contributory role. Two thousand seven hundred and ninety-two adult hypertensive patients were managed over the study period. Of them, 218 (7.8%) were newly diagnosed and studied. There were 94 males and 124 females. Seventy-seven (35.3%) were aged 60 years and above with equal frequency in the gender. One hundred and seventy-eight (81.7%) cases had combined systolic and diastolic pressures. Twenty-nine (13.3%) patients had systolic hypertension. Twenty-five (86.2%) of these 29 were aged 50 years and above and 20 (69.0%) were aged 60 years and above. Eleven (5.0%) patients had isolated diastolic hypertension and they were all in the age bracket 40-49 years. Systolic blood pressure was found to be rising with advancing age while diastolic blood pressure peaked at mid 40's and declined. Target organ damage occurred more frequently with systolic hypertension and advancing age than with diastolic hypertension. Systolic hypertension occurred more frequently in this series of adult Nigerians with hypertension. It was higher with advancing age and associated with more target organ

  11. Reducing maternal mortality: Systolic blood pressure

    African Journals Online (AJOL)

    2006-03-21

    Mar 21, 2006 ... While deaths due to fluid overload have ... of better fluid balance management, we have made .... systolic blood pressure plays a significant role in the .... one looks at the work of Martin et al.5 ... Promoting Healthy Life.

  12. Systolic automata for VLSI on balanced trees

    Energy Technology Data Exchange (ETDEWEB)

    Culik, K Ii; Gruska, J; Salomaa, A

    1983-01-01

    Systolic tree automata with a binary (or, more generally, balanced) underlying tree are investigated. The main emphasis is on input conditions, decidability, and characterization of acceptable languages. 4 references.

  13. Potential Cislunar and Interplanetary Proving Ground Excursion Trajectory Concepts

    Science.gov (United States)

    McGuire, Melissa L.; Strange, Nathan J.; Burke, Laura M.; MacDonald, Mark A.; McElrath, Timothy P.; Landau, Damon F.; Lantoine, Gregory; Hack, Kurt J.; Lopez, Pedro

    2016-01-01

    NASA has been investigating potential translunar excursion concepts to take place in the 2020s that would be used to test and demonstrate long duration life support and other systems needed for eventual Mars missions in the 2030s. These potential trajectory concepts could be conducted in the proving ground, a region of cislunar and near-Earth interplanetary space where international space agencies could cooperate to develop the technologies needed for interplanetary spaceflight. Enabled by high power Solar Electric Propulsion (SEP) technologies, the excursion trajectory concepts studied are grouped into three classes of increasing distance from the Earth and increasing technical difficulty: the first class of excursion trajectory concepts would represent a 90-120 day round trip trajectory with abort to Earth options throughout the entire length, the second class would be a 180-210 day round trip trajectory with periods in which aborts would not be available, and the third would be a 300-400 day round trip trajectory without aborts for most of the length of the trip. This paper provides a top-level summary of the trajectory and mission design of representative example missions of these three classes of excursion trajectory concepts.

  14. Compensation for large thorax excursions in EIT imaging.

    Science.gov (United States)

    Schullcke, B; Krueger-Ziolek, S; Gong, B; Mueller-Lisse, U; Moeller, K

    2016-09-01

    Besides the application of EIT in the intensive care unit it has recently also been used in spontaneously breathing patients suffering from asthma bronchiole, cystic fibrosis (CF) or chronic obstructive pulmonary disease (COPD). In these cases large thorax excursions during deep inspiration, e.g. during lung function testing, lead to artifacts in the reconstructed images. In this paper we introduce a new approach to compensate for image artifacts resulting from excursion induced changes in boundary voltages. It is shown in a simulation study that boundary voltage change due to thorax excursion on a homogeneous model can be used to modify the measured voltages and thus reduce the impact of thorax excursion on the reconstructed images. The applicability of the method on human subjects is demonstrated utilizing a motion-tracking-system. The proposed technique leads to fewer artifacts in the reconstructed images and improves image quality without substantial increase in computational effort, making the approach suitable for real-time imaging of lung ventilation. This might help to establish EIT as a supplemental tool for lung function tests in spontaneously breathing patients to support clinicians in diagnosis and monitoring of disease progression.

  15. Correlation between glycemic excursion by CGMS and diabetic retinopathy among Type 2 diabetes mellitus

    International Nuclear Information System (INIS)

    Pu Li; Ji Ning; Zhu Wei

    2011-01-01

    Objective: To investigate correlation between glycemic excursion by CGMS and diabetic retinopathy among type 2 diabetes mellitus. Methods: Used continuous glucose monitoring system (CGMS) to monitoring glycemic excursion within a day of twenty four patients with type 2 diabetes mellitus, and inspect fundus photography, correlation was analyzed. Results: Glycemic excursion might reveal the risk for diabetic retinopathy better than HbA1c does. Conclusion: Diabetic retinopathy may correlate with glycemic excursion. (authors)

  16. Tube to tube excursive instability - sensitivities and transients

    International Nuclear Information System (INIS)

    Brown, M.; Layland, M.W.

    1980-01-01

    A simple basic analysis of excursive instability in a boiler tube shows how it depends upon operating conditions and physical properties. A detailed mathematical model of an AGR boiler is used to conduct a steady state parameter sensitivity survey. It is possible from this basis to anticipate the effects of changes in operating conditions and changes in design parameters upon tube to tube stability. Dynamic responses of tubes operating near the stability threshold are examined using a mathematical model. Simulated excursions are triggered by imparting small abrupt pressure changes on the boiler inlet pressure. The influences of the magnitude of the pressure change, waterside friction factor and gas side coupling between tubes are examined. (author)

  17. Magnetosheath excursion and the relevant transport process at the magnetopause

    Directory of Open Access Journals (Sweden)

    C. L. Cai

    2009-08-01

    Full Text Available A large-amplitude excursion of the magnetosheath (MS in quiet solar wind conditions on 17 March 2004 was recorded simultaneously by the Cluster and TC-1 spacecraft. During this period, the IMF Bz was entirely northward. The coherence between the bow shock motion and magnetopause (MP motion is revealed and the excursion velocities of the bow shock motion are analyzed. In addition, the relevant plasma transport phenomenon in the form of flux fluctuations below the ion gyrofrequency at the MP is exposed and is interpreted as manifestation of the drift instability. Correlated observations on charge accumulation and electrostatic potential perturbation are recorded by electron measurements in high energy regime, and also the eventual cross-field vortex motion in the nonlinear stage and the consequential mass exchange are exhibited. The present investigation gives some new insight into the MS plasma transport mechanism across the subsolar MP region in quiet solar wind conditions during a period of northward IMF.

  18. Estimates of fission yields in nuclear criticality excursions

    International Nuclear Information System (INIS)

    Choi, J.S.; Thompson, J.W.; Reed, R.

    1995-06-01

    There is a need for computer simulation of hypothetical criticality excursions involving significant quantities of fissionable materials, especially in fissile aqueous system. The need arises due to the requirements for the emergency planning of facilities where the fissionable materials are handled, processed, or stored; and the regulatory requirements associated with facility operation or conversion. It is proposed here that a data base of fission yeilds for critical experiments and known accidents (both aqueous and solid) should be generated by using existing or new computer codes. The success in compiling this data base would provide useful source-terms for criticality excursions, realistic estimates of emergency-response boundary, as well as a replacement for the ''rule-of-thumb'' or ''bounding'' method. 10 refs

  19. Geology and prospecting in the Carpatians conference excursion guide

    Directory of Open Access Journals (Sweden)

    Jacko Stanislav

    2000-06-01

    Full Text Available We would like to welcome you to the excursions finalizing the Geology and prospecting in the Carpathians Conference, Her¾any –2000. The aim of the excursions is to provide you an overview of these Western Carpathian lithostructural units – and their mineralization respectively, research progress of which has been (at that time closely connected with personal investigation enthusiasm of our Professors - the founders of our Faculty. The current state of geological development knowledge of principal structural units of the Western Carpathians is outlined in papers included in special issue of Mineralia Slovaca magazine you have received at the begining of the Conference. For this reason the content of this Excursion quide is exclusively concentrated to description of routes localities. Broader geological relationships of particular outcrops is possible to find in attached Geological map of the Slovak Republic 1:100 000. The organizers of the excursions gratefully acknowledge the efforts of all colleagues who contributed to this quide. We also like to express our thanks for the financial support to Slovak VEGA grant Agency (Grant No:1/7389/2 and to the following organizations: Association of Metallurgy, Minig Industry and Geology of Slovak Republic, Slovak Geological Society, Management of TU Košice, SAPTU Foundation of TU Košice, Geological Survey of the Slovak Republic Betox JSC. Košice, SMW JSC. Jelšava, Uranpress Ltd. Spišská Nová Ves, TESCO Košice, ŽELBA-Siderite JSC. Nižná Slaná and ŽELBA –JSC. Spišská Nová Ves.

  20. Age and Structure of the Laschamp Geomagnetic Excursion

    Science.gov (United States)

    Scaillet, S.; Laj, C.; Kissel, C.; Guillou, H.; Singer, B. S.

    2004-12-01

    The age of the Laschamp geomagnetic excursion has been recently re-investigated using unspiked K/Ar and Ar/Ar techniques (Guillou et al., Session V01, this conference). The new age determination of 40.4 +/- 2.0 ka (2 sigma) is more precise than those previously reported in the literature and agrees precisely with that deduced from the GLOPIS-75 sedimentary paleointensity stack calibrated against the GISP2 ice core chronology. Two of the North Atlantic cores used in GLOPIS-75 (MD95-2034 and PS2644-5) yield rather detailed transitional VGP paths. In the two cases the paths show large similarities, with the VGP initially descending along mid-western Pacific, then returning to normal polarities with a large clockwise loop over Africa and Europe. Differences in the highest southern latitudes reached by the VGP can be explained assuming more different degrees of smearing of the paleomagnetic record due to differences in sedimentation rate in the two cores. In the most detailed record, MD95-2034 , two smaller loops are present preceding the main excursion. In the two cores, the excursion is characterized by a significant drop in intensity. The reversal paths observed for the Laschamp event are very close in position to those reported for the Icelandic Basin Event (IBE) from sites in the North Atlantic and the South China Sea (Laj et al., this conference) but differ in the sense of looping: while a clockwise loop is observed here, a counterclockwise loop is observed for the IBE. Despite this difference, the similarity of the transitional records tends to suggest that a similar, relatively simple, geometry has dominated the two excursions and therefore that similar dynamo mechanisms have prevailed during the reversal process.

  1. Searching Algorithms Implemented on Probabilistic Systolic Arrays

    Czech Academy of Sciences Publication Activity Database

    Kramosil, Ivan

    1996-01-01

    Roč. 25, č. 1 (1996), s. 7-45 ISSN 0308-1079 R&D Projects: GA ČR GA201/93/0781 Keywords : searching algorithms * probabilistic algorithms * systolic arrays * parallel algorithms Impact factor: 0.214, year: 1996

  2. Is hydrotherapy an appropriate form of exercise for elderly patients with biventricular systolic heart failure?

    Science.gov (United States)

    Sveälv, Bente Grüner; Täng, Margareta Scharin; Cider, Åsa

    2012-01-01

    Hydrotherapy (exercise in warm water) is considered to be a safe and beneficial method to use in the rehabilitation of stable heart failure patients, but there is little information on the effect of the increased venous return and enhanced preload in elderly patients with biventricular heart failure. We present a case of an elderly man who was recruited to participate in a hydrotherapy study. We compared echocardiographic data during warm water immersion with land measurements, and observed increases in stroke volume from 32 mL (land) to 42 mL (water), left ventricular ejection fraction from 22% to 24%, left ventricular systolic velocity from 4.8 cm/s to 5.0 cm/s and left atrioventricular plane displacement from 2.1 mm to 2.2 mm. By contrast, right ventricular systolic velocity decreased from 11.2 cm/s to 8.4 cm/s and right atrioventricular plane displacement from 8.1 mm to 4.7 mm. The tricuspid pressure gradient rose from 18 mmHg on land to 50 mmHg during warm water immersion. Thus, although left ventricular systolic function was relatively unaffected during warm water immersion, we observed a decrease in right ventricular function with an augmented right ventricular pressure. We recommend further investigations to observe the cardiac effect of warm water immersion on patients with biventricular systolic heart failure and at risk of elevated right ventricular pressure. PMID:23341846

  3. SYSTOLIC HYPERTENSION. IMPACT ON CEREBROVASCULAR DISEASE

    Directory of Open Access Journals (Sweden)

    Juan Eloy Cruz Quesada

    2011-08-01

    Full Text Available Background: Atherosclerosis is a multifactor process in which several risk factors are involved. It is the leading cause of death and morbidity in hospital admitted patients, and it may cause a marked decrease in blood flow to all organs of the body.Objective: To determine the impact of systolic hypertension on cerebrovascular disease.Methods: A cross-sectional, observational and analytical study was conducted in 59 death patients who suffered from hypertension. Cerebral arteries were analyzed and atherosclerotic lesion and its variety were quantified by using the atherometric system. The different types of hypertension were considered. Statistical (central tendency measures and comparative (comparison test based on Student’s arithmetic t-test procedures were used.Results: Recent strokes were more frequent in systodiastolic hypertensive patients. There was no significant difference in the injury onset age for both sexes, but women with systolic hypertension were significantly more damaged (from a morphometric point of view. Significant correlation for both groups of hypertensive patients was observed between type of stroke and atherometric system variables.Conclusions: Systolic hypertension is an important factor in the genesis of cerebrovascular disease and is associated with the progression of atherosclerotic plaque.

  4. Mitral annular systolic velocity as a marker of preclinical systolic dysfunction among patients with arterial hypertension

    Directory of Open Access Journals (Sweden)

    Daskalov Ivaylo Rilkov

    2012-11-01

    Full Text Available Abstract Background The aim of this study was to investigate early changes in left ventricular longitudinal systolic function in patients with hypertension (HTN with and without concomitant diastolic dysfunction (DD and the clinical implications of these findings. Method We enrolled 299 patients with HTN and 297 age-matched patients with HTN and DD and compared both groups with an age-matched control group consisting of 100 healthy subjects. The long axis systolic function was investigated by determining the average peak systolic velocity of the septal and lateral mitral sites (Smavg using spectral pulsed wave tissue Doppler imaging (TDI. Results We found a strong negative trend toward the reduction of velocity, which is dependent on the grade of HTN, on the magnitude of DD, and also on the gender and age of the subjects (r=−0.891/-0.580; p Conclusion The strength of the study is the analysis of incremental changes in longitudinal contraction in patients with different stage of HTN but not so many the classification of the degree of systolic dysfunction. The importance of our results lies in the fact that these initial changes in systolic contraction could be used as an early sign that should prompt optimization of the treatment of HTN.

  5. Treatment of anemia with darbepoetin alfa in systolic heart failure

    DEFF Research Database (Denmark)

    Swedberg, Karl; Young, James B; Anand, Inder S

    2013-01-01

    Patients with systolic heart failure and anemia have worse symptoms, functional capacity, and outcomes than those without anemia. We evaluated the effects of darbepoetin alfa on clinical outcomes in patients with systolic heart failure and anemia.......Patients with systolic heart failure and anemia have worse symptoms, functional capacity, and outcomes than those without anemia. We evaluated the effects of darbepoetin alfa on clinical outcomes in patients with systolic heart failure and anemia....

  6. Global characteristics of geomagnetic excursions as seen in global empirical models and a numerical geodynamo simulation

    Science.gov (United States)

    Korte, M. C.; Wardinski, I.; Brown, M. C.

    2016-12-01

    Paleomagnetic results from sediments and lava flows provide observational evidence of numerous geomagnetic excursions throughout Earth's history. Two new spherical harmonic geomagnetic field models covering 50-30 ka, including the Laschamp ( 41ka) and Mono Lake ( 32-35 ka) excursions allow us to characterize the global behaviour of these events, both at Earth's surface and the core-mantle boundary. We investigate the evolution of dipole and large-scale non-dipole power throughout the duration of the model and the morphology of the large-scale radial field at the core-mantle boundary. The models suggest clear differences in both the decrease in axial dipole strength and dipole tilt between the two excursions and unlike the previously published model by Leonhardt et al. (2009), they suggest some increase of non-dipole power during the early and late stages of the Laschamp excursion. Global characteristics from the models can be directly compared with results from numerical simulations. We do so for several excursions generated by a numerical simulation driven by purely compositional convection, which appears Earth-like in terms of excursion and reversal occurrence frequency. Excursions from this simulation show differing characteristics, including differences in spectral power evolution. Some cases show similarities to the Laschamp and Mono Lake excursions in the spherical harmonic models. In particular they all indicate that excursions are mainly governed by the axial dipole term and equatorial dipole terms play a minor role.

  7. Vertical orbit excursion fixed field alternating gradient accelerators

    Directory of Open Access Journals (Sweden)

    Stephen Brooks

    2013-08-01

    Full Text Available Fixed field alternating gradient (FFAG accelerators with vertical orbit excursion (VFFAGs provide a promising alternative design for rings with fixed-field superconducting magnets. They have a vertical magnetic field component that increases with height in the vertical aperture, yielding a skew quadrupole focusing structure. Scaling-type VFFAGs are found with fixed tunes and no intrinsic limitation on momentum range. This paper presents the first multiparticle tracking of such machines. Proton driver rings to accelerate the 800 MeV beam from the ISIS synchrotron are presented, in terms of both magnet field geometry and longitudinal behavior during acceleration with space charge. The 12 GeV ring produces an output power of at least 2.18 MW. Possible applications of VFFAGs to waste transmutation, hadron therapy, and energy-recovery electron accelerators are also discussed.

  8. Proofs of the Cantor-Bernstein theorem a mathematical excursion

    CERN Document Server

    Hinkis, Arie

    2013-01-01

    This book offers an excursion through the developmental area of research mathematics. It presents some 40 papers, published between the 1870s and the 1970s, on proofs of the Cantor-Bernstein theorem and the related Bernstein division theorem. While the emphasis is placed on providing accurate proofs, similar to the originals, the discussion is broadened to include aspects that pertain to the methodology of the development of mathematics and to the philosophy of mathematics. Works of prominent mathematicians and logicians are reviewed, including Cantor, Dedekind, Schröder, Bernstein, Borel, Zermelo, Poincaré, Russell, Peano, the Königs, Hausdorff, Sierpinski, Tarski, Banach, Brouwer and several others mainly of the Polish and the Dutch schools. In its attempt to present a diachronic narrative of one mathematical topic, the book resembles Lakatos’ celebrated book Proofs and Refutations. Indeed, some of the observations made by Lakatos are corroborated herein. The analogy between the two books is clearly an...

  9. The main problems of Cycling excursions on the Moscow market

    Directory of Open Access Journals (Sweden)

    Sergeev A.A.

    2016-12-01

    Full Text Available the article discusses the reasons of rejection of Bicycle transport. It is noted that the main causes are the heavy ecological situation in Moscow and a large number of vehicles. The authors note that according to the Department of natural resources 90% of pollution is caused by the road transport. To solve this problem, the authors offer to use bicycles and to develop a network of cycle routes and excursions, improve the quality of bike paths to connect them together, to approve the rules of the road (SDA for cyclists, which will reduce the number of accidents with their participation. The article presents strong arguments in favor of the development and use of bicycles and bicycle tours.

  10. Excursions to nuclear facilities in the Federal Republic of Germany

    International Nuclear Information System (INIS)

    1980-12-01

    Promoting young talents in the field of nuclear technology is considered one of the most important tasks the Kerntechnische Gesellschaft e.V. (Society for Nuclear Engineering) tries to fulfill in many ways. It has developed a curriculum for the specialty of nuclear technology, provides funds for attending conferences and gives financial support to student members. In line with these efforts to promote young talents, the Kerntechnische Gesellschaft now submits a list of nuclear facilities where to special excursions may be made in the course of corresponding training programmes. State-owned and private research and development centres, industrial factories and electricity-generating nuclear power plants as well as nuclear fuel cycle centres are thus concerned. (orig.) [de

  11. Translator’s inferential excursions, with imagination in the background

    Directory of Open Access Journals (Sweden)

    Bożena Tokarz

    2014-01-01

    Full Text Available In a literary work, signals that trigger reader’s inferential excursions allow the reader’s imagination to identify with and control the represented world. They constitute an important element of sense-generating mechanism. Thanks to imagination, the translator imitates the inferential mechanism of the original on various level’s of the text’s structure, activating the imagination of the reader. The translator’s imagination is bi- or multivalent in having the linguistic-semiotic, literary, and cultural quality. Although it manifests itself in language, it goes beyond the boundaries of language. Imagination is a form of consciousness which has no object of its own, and a medium connecting a specific non-imaginary knowledge with representations. It constitutes a mind faculty shaped on the basis of sensory and mental perception. It is derived from individual principles of perception and cognition data processing. It usually requires a stymulus to activate the capabilities of the imagining subject. As a mind faculty, imagination is based on the mental capability common to all people, which is the ability to create chains of associations.Translator’s respect for inferential excursions in the original text is necessary for retaining the original meaning, regardless of whether they occur on the phonetic-phonological level (as in Ionesco’s The Chairs, or on the level of image-semantic and syntactic relations (as in translation of Apollinaire’s Zone, or on the level of syntax (as in translation of Mrożek’s short stories into Slovenian, or on the level of cultural communication (as in Slovenian translation of Gombrowicz’s Trans-Atlantic.

  12. Systolic hypertension: an increasing clinical challenge in Asia

    Science.gov (United States)

    Park, Jeong Bae; Kario, Kazuomi; Wang, Ji-Guang

    2015-01-01

    Systolic hypertension, the predominant form of hypertension in patients aged over 50–60 years, is a growing health issue as the Asian population ages. Elevated systolic blood pressure is mainly caused by arterial stiffening, resulting from age-related vascular changes. Elevated systolic pressure increases the risk of cardiovascular disease, mortality and renal function decline, and this risk may increase at lower systolic pressure levels in Asian than Western subjects. Hence, effective systolic pressure lowering is particularly important in Asians yet blood pressure control remains inadequate despite the availability of numerous antihypertensive medications. Reasons for poor blood pressure control include low awareness of hypertension among health-care professionals and patients, under-treatment, and tolerability problems with antihypertensive drugs. Current antihypertensive treatments also lack effects on the underlying vascular pathology of systolic hypertension, so novel drugs that address the pathophysiology of arterial stiffening are needed for optimal management of systolic hypertension and its cardiovascular complications. PMID:25503845

  13. 49 CFR 38.177 - Ferries, excursion boats and other vessels. [Reserved

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Ferries, excursion boats and other vessels... DISABILITIES ACT (ADA) ACCESSIBILITY SPECIFICATIONS FOR TRANSPORTATION VEHICLES Other Vehicles and Systems § 38.177 Ferries, excursion boats and other vessels. [Reserved] ...

  14. Optimization of vehicle weight for Mars excursion missions

    Science.gov (United States)

    Ferebee, Melvin J., Jr.

    1991-01-01

    The excursion class mission to Mars is defined as a mission with one year durations coupled with a stay time of up to 30 days. The fuel budget for such a mission is investigated. The overall figure of merit in such an assessment is the vehicle weight ratio, the ratio between the wet vehicle weight to the dry vehicle weight. It is necessary to minimize the overall fuel budget for the mission in order to maximize the benefits that could be obtained by sending humans to Mars. Assumptions used in the analysis are: each mission will depart and terminate in low-earth-orbit (LEO) (500 km circular) and the maximum stay time at Mars is 30 days. The maximum mission duration is one year (355-375 days). The mass returned to LEO is 135,000 kg, the dropoff mass left at Mars is 168,000 kg. Three propulsive techniques for atmospheric interface are investigated: aerobraking, all-chemical propulsion, and nuclear thermal propulsion. By defining the fuel requirements, the space transfer vehicle's configuration is defined.

  15. Hydrodynamic analysis of the LMFBR prompt burst excursion (PBE) experiment

    International Nuclear Information System (INIS)

    Young, M.F.

    1977-01-01

    A series of in-pile experiments has been conducted at Sandia Laboratories to provide information on pressure levels and conversion of thermal energy into mechanical work in LMFBR cores during hypothetical, superprompt-critical excursions. Pressures generated in these experiments are recorded by a pressure transducer located at the top and bottom of a sodium channel surrounding a single, fresh UO 2 fuel pin. Work energy conversion is measured by a linear motion transducer connected to a piston at the top of the sodium column. Since the pressure transducers are located fairly far from the location of pin failure, it becomes necessary to determine the effect of channel geometry and piston motion on the observed pressure data. A two-dimensional, hydrodynamic analysis of pressure pulse propagation in the fuel pin-coolant channel geometry was therefore performed using the CSQII computer code. The initial series of PBE experiments consists of single, fresh UO 2 pins surrounded by a sodium-filled or dry-coolant channel contained in a closed test capsule. The capsule is subjected to a maximum pulse in the Annular Core Pulse Reactor (ACPR) resulting in an energy deposition of from 2350 to 2900 J/g (14 and 20 percent enriched pins). The pulse width at half maximum (PWHM) is about 5 ms

  16. Scope Complexity Options Risks Excursions (SCORE) Factor Mathematical Description.

    Energy Technology Data Exchange (ETDEWEB)

    Gearhart, Jared Lee [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Samberson, Jonell Nicole [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Shettigar, Subhasini [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Jungels, John [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Welch, Kimberly M. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Jones, Dean A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-03-01

    The purpose of the Scope, Complexity, Options, Risks, Excursions (SCORE) model is to estimate the relative complexity of design variants of future warhead options, resulting in scores. SCORE factors extend this capability by providing estimates of complexity relative to a base system (i.e., all design options are normalized to one weapon system). First, a clearly defined set of scope elements for a warhead option is established. The complexity of each scope element is estimated by Subject Matter Experts (SMEs), including a level of uncertainty, relative to a specific reference system. When determining factors, complexity estimates for a scope element can be directly tied to the base system or chained together via comparable scope elements in a string of reference systems that ends with the base system. The SCORE analysis process is a growing multi-organizational Nuclear Security Enterprise (NSE) effort, under the management of the NA-12 led Enterprise Modeling and Analysis Consortium (EMAC). Historically, it has provided the data elicitation, integration, and computation needed to support the out-year Life Extension Program (LEP) cost estimates included in the Stockpile Stewardship Management Plan (SSMP).

  17. Power Excursion Accident Analysis of Research Water Reactor

    International Nuclear Information System (INIS)

    Khaled, S.M.; Doaa, G.M.

    2009-01-01

    A three-dimensional neutronic code POWEX-K has been developed, and it has been coupled with the sub-channel thermal-hydraulic core analysis code SV based on the Single Mass Velocity Model. This forms the integrated neutronic/thermal hydraulics code system POWEX-K/SV for the accident analysis. The Training and Research Reactors at Budapest University of Technology and Economics (BME-Reactor) has been taken as a reference reactor. The cross-section generation procedure based on WIMS. The code uses an implicit difference approach for both the diffusion equations and thermal-hydraulics modules, with reactivity feedback effects due to coolant and fuel temperatures. The code system was applied to analyzing power excursion accidents initiated by ramp reactivity insertion of 1.2 $. The results show that the reactor is inherently safe in case of such accidents i.e. no core melt is expected even if the safety rods do not fall into the core

  18. Etiology and diagnosis of systolic murmurs in adults.

    Science.gov (United States)

    McGee, Steven

    2010-10-01

    It is unknown whether echocardiography can provide insights into the origin of systolic murmurs and the modern value of bedside cardiovascular diagnosis. The author examined 376 inpatients and compared their physical findings to transthoracic echocardiography, exploring the associations between echocardiography and systolic murmurs and investigating the diagnostic accuracy of physical examination for pathologic murmurs. Four echocardiographic variables predict the presence of systolic murmurs: peak aortic velocity (P onomatopoeia and classifying systolic murmurs into 1 of 6 patterns is diagnostically helpful. Copyright © 2010. Published by Elsevier Inc.

  19. The Excursion Set Theory of Halo Mass Functions, Halo Clustering, and Halo Growth

    Science.gov (United States)

    Zentner, Andrew R.

    I review the excursion set theory with particular attention toward applications to cold dark matter halo formation and growth, halo abundance, and halo clustering. After a brief introduction to notation and conventions, I begin by recounting the heuristic argument leading to the mass function of bound objects given by Press and Schechter. I then review the more formal derivation of the Press-Schechter halo mass function that makes use of excursion sets of the density field. The excursion set formalism is powerful and can be applied to numerous other problems. I review the excursion set formalism for describing both halo clustering and bias and the properties of void regions. As one of the most enduring legacies of the excursion set approach and one of its most common applications, I spend considerable time reviewing the excursion set theory of halo growth. This section of the review culminates with the description of two Monte Carlo methods for generating ensembles of halo mass accretion histories. In the last section, I emphasize that the standard excursion set approach is the result of several simplifying assumptions. Dropping these assumptions can lead to more faithful predictions and open excursion set theory to new applications. One such assumption is that the height of the barriers that define collapsed objects is a constant function of scale. I illustrate the implementation of the excursion set approach for barriers of arbitrary shape. One such application is the now well-known improvement of the excursion set mass function derived from the "moving" barrier for ellipsoidal collapse. I also emphasize that the statement that halo accretion histories are independent of halo environment in the excursion set approach is not a general prediction of the theory. It is a simplifying assumption. I review the method for constructing correlated random walks of the density field in the more general case. I construct a simple toy model to illustrate that excursion set

  20. 3-D Velocity Estimation for Two Planes in vivo

    DEFF Research Database (Denmark)

    Holbek, Simon; Pihl, Michael Johannes; Ewertsen, Caroline

    2014-01-01

    3-D velocity vectors can provide additional flow information applicable for diagnosing cardiovascular diseases e.g. by estimating the out-of-plane velocity component. A 3-D version of the Transverse Oscillation (TO) method has previously been used to obtain this information in a carotid flow...... and stored on the experimental scanner SARUS. The full 3-D velocity profile can be created and examined at peak-systole and end-diastole without ECG gating in two planes. Maximum out-of-plane velocities for the three peak-systoles and end-diastoles were 68.5 5.1 cm/s and 26.3 3.3 cm/s, respectively....... In the longitudinal plane, average maximum peak velocity in flow direction was 65.2 14.0 cm/s at peak-systole and 33.6 4.3 cm/s at end-diastole. A commercial BK Medical ProFocus UltraView scanner using a spectral estimator gave 79.3 cm/s and 14.6 cm/s for the same volunteer. This demonstrates that real-time 3-D...

  1. Invasively Measured Aortic Systolic Blood Pressure and Office Systolic Blood Pressure in Cardiovascular Risk Assessment: A Prospective Cohort Study

    DEFF Research Database (Denmark)

    Laugesen, Esben; Knudsen, Søren T; Hansen, Klavs W

    2016-01-01

    Aortic systolic blood pressure (BP) represents the hemodynamic cardiac and cerebral burden more directly than office systolic BP. Whether invasively measured aortic systolic BP confers additional prognostic value beyond office BP remains debated. In this study, office systolic BP and invasively......) and with myocardial infarction in patients without diabetes mellitus (hazard ratio, 1.07 [95% confidence interval, 1.02-1.12] and 1.05 [95% confidence interval, 1.01-1.10], respectively). In models including both BP measurements, aortic BP lost statistical significance and aortic BP did not confer improvement...

  2. Hyolaryngeal excursion as the physiological source of swallowing accelerometry signals

    International Nuclear Information System (INIS)

    Zoratto, D C B; Chau, T; Steele, C M

    2010-01-01

    Swallowing dysfunction, or dysphagia, is a serious condition that can result from any structural or neurological impairment (such as stroke, neurodegenerative disease or brain injury) that affects the swallowing mechanism. The gold-standard method of instrumental swallowing assessment is an x-ray examination known as the videofluoroscopic swallowing study, which involves radiation exposure. Consequently, there is interest in exploring the potential of less invasive methods, with lesser risks of biohazard, to accurately detect swallowing abnormalities. Accelerometry is one such technique, which measures the epidermal vibration signals on a patient's neck during swallowing. Determining the utility of accelerometry signals for detecting dysphagia requires an understanding of the physiological source of the vibrations that are measured on the neck during swallowing. The purpose of the current study was to determine the extent to which movement of the hyoid bone and larynx contributes to the vibration signal that is registered during swallowing accelerometry. This question was explored by mapping the movement trajectories of the hyoid bone and the arytenoid cartilages from lateral videofluoroscopy recordings collected during thin liquid swallowing, and comparing these trajectories to time-linked signals obtained from a dual-axis accelerometer placed on the neck, just anterior to the cricoid cartilage. Participants for this study included 43 adult patients referred for videofluoroscopic swallowing studies to characterize the nature and severity of suspected neurogenic dysphagia. A software program was created to allow frame-by-frame tracking of structural movement on the videofluoroscopy recordings. These movement data were then compared to the integrated acceleration data using multiple linear regressions. The results concur with previous studies, implicating hyolaryngeal excursion as the primary physiological source of swallowing accelerometry signals, with both

  3. Multi-unit shutdown due to boiler feedwater chemical excursion

    International Nuclear Information System (INIS)

    Diebel, M.E.

    1991-01-01

    Ontario Hydro's Bruce Nuclear Generating Station 'B' consists of four 935 W CANDU units located on the east shore of Lake Huron in the province of Ontario, Canada. On July 25 and 26, 1989 three of the four operating units were shutdown due to boiler feedwater chemical excursions initiated by a process upset in the Water Treatment Plant that provides demineralized make-up water to all four units. The chemicals that escaped from an ion exchange vessel during a routine regeneration very quickly spread through the condensate make-up system and into the boiler feedwater systems. This resulted in boiler sulfate levels exceeding shutdown limits. A total of 260 GWH of electrical generation was unexpectedly made unavailable to the grid at a time of peak seasonal demand. This event exposed several unforeseen deficiencies and vulnerabilities in the automatic demineralized water make-up quality protection scheme, system designs, operating procedures and the ability of operating personnel to recognize and appropriately respond to such an event. The combination of these factors contributed towards turning a minor system upset into a major multi-unit shutdown. This paper provides the details of the actual event initiation in the Water Treatment Plant and describes the sequence of events that led to the eventual shutdown of three units and near shutdown of the fourth. The design inadequacies, procedural deficiencies and operating personnel responses and difficulties are described. The process of recovering from this event, the flushing out of system piping, boilers and the feedwater train is covered as well as our experiences with setting up supplemental demineralized water supplies including trucking in water and the use of rental trailer mounted demineralizing systems. System design, procedural and operational changes that have been made and that are still being worked on in response to this event are described. The latest evidence of the effect of this event on boiler tube

  4. Spatial and temporal patterns of subtidal and intertidal crabs excursions

    Science.gov (United States)

    Silva, A. C. F.; Boaventura, D. M.; Thompson, R. C.; Hawkins, S. J.

    2014-01-01

    Highly mobile predators such as fish and crabs are known to migrate from the subtidal zone to forage in the intertidal zone at high-tide. The extent and variation of these habitat linking movements along the vertical shore gradient have not been examined before for several species simultaneously, hence not accounting for species interactions. Here, the foraging excursions of Carcinus maenas (L.), Necora puber (Linnaeus, 1767) and Cancer pagurus (Linnaeus, 1758) were assessed in a one-year mark-recapture study on two replicated rocky shores in southwest U.K. A comparison between the abundance of individuals present on the shore at high-tide with those present in refuges exposed at low-tide indicated considerable intertidal migration by all species, showing strong linkage between subtidal and intertidal habitats. Estimates of population size based on recapture of marked individuals indicated that an average of ~ 4000 individuals combined for the three crab species, can be present on the shore during one tidal cycle. There was also a high fidelity of individuals and species to particular shore levels. Underlying mechanisms for these spatial patterns such as prey availability and agonistic interactions are discussed. Survival rates were estimated using the Cormack-Jolly-Seber model from multi-recapture analysis and found to be considerably high with a minimum of 30% for all species. Growth rates were found to vary intraspecifically with size and between seasons. Understanding the temporal and spatial variations in predation pressure by crabs on rocky shores is dependent on knowing who, when and how many of these commercially important crab species depend on intertidal foraging. Previous studies have shown that the diet of these species is strongly based on intertidal prey including key species such as limpets; hence intertidal crab migration could be associated with considerable impacts on intertidal assemblages.

  5. Limitations of middle cerebral artery peak systolic velocity in the ...

    African Journals Online (AJOL)

    We present a case of a mother with severe pre-eclampsia at 32 weeks' gestation and non-immune fetal hydrops without obvious cause. Since the. MCA peak systolic velocity (PSV) was ... Limitations of middle cerebral artery peak systolic velocity .... [7] found MCA PSV of value in 9 women with chronic abruption, but in 5.

  6. Exercise training in older patients with systolic heart failure

    DEFF Research Database (Denmark)

    Prescott, Eva; Hjardem-Hansen, Rasmus; Dela, Flemming

    2009-01-01

    Training improves exercise capacity in patients with heart failure (CHF) but most evidence is on selected younger patients with systolic CHF.......Training improves exercise capacity in patients with heart failure (CHF) but most evidence is on selected younger patients with systolic CHF....

  7. Existence of Projective Planes

    OpenAIRE

    Perrott, Xander

    2016-01-01

    This report gives an overview of the history of finite projective planes and their properties before going on to outline the proof that no projective plane of order 10 exists. The report also investigates the search carried out by MacWilliams, Sloane and Thompson in 1970 [12] and confirms their result by providing independent verification that there is no vector of weight 15 in the code generated by the projective plane of order 10.

  8. Maximum Acceptable Vibrato Excursion as a Function of Vibrato Rate in Musicians and Non-musicians

    DEFF Research Database (Denmark)

    Vatti, Marianna; Santurette, Sébastien; Pontoppidan, Niels H.

    2014-01-01

    and, in most listeners, exhibited a peak at medium vibrato rates (5–7 Hz). Large across-subject variability was observed, and no significant effect of musical experience was found. Overall, most listeners were not solely sensitive to the vibrato excursion and there was a listener-dependent rate...... for which larger vibrato excursions were favored. The observed interaction between maximum excursion thresholds and vibrato rate may be due to the listeners’ judgments relying on cues provided by the rate of frequency changes (RFC) rather than excursion per se. Further studies are needed to evaluate......Human vibrato is mainly characterized by two parameters: vibrato extent and vibrato rate. These parameters have been found to exhibit an interaction both in physical recordings of singers’ voices and in listener’s preference ratings. This study was concerned with the way in which the maximum...

  9. Further development and verification of the calculating programme Felix for the simulation of criticality excursions

    International Nuclear Information System (INIS)

    Weber, J.; Denk, W.

    1985-01-01

    An improved version of the FELIX programme was applied to varify excursion experiments 01, 03 through 07, and 13. The correspondence of experiments and verification was good. Programme points to be further developed are shown. (orig.) [de

  10. Systolic array processing of the sequential decoding algorithm

    Science.gov (United States)

    Chang, C. Y.; Yao, K.

    1989-01-01

    A systolic array processing technique is applied to implementing the stack algorithm form of the sequential decoding algorithm. It is shown that sorting, a key function in the stack algorithm, can be efficiently realized by a special type of systolic arrays known as systolic priority queues. Compared to the stack-bucket algorithm, this approach is shown to have the advantages that the decoding always moves along the optimal path, that it has a fast and constant decoding speed and that its simple and regular hardware architecture is suitable for VLSI implementation. Three types of systolic priority queues are discussed: random access scheme, shift register scheme and ripple register scheme. The property of the entries stored in the systolic priority queue is also investigated. The results are applicable to many other basic sorting type problems.

  11. Sedimentary and Volcanic Records of the Laschamp and Mono Lake Excursions from Australia and New Zealand

    Science.gov (United States)

    Ingham, E. M.; Roberts, A. P.; Turner, G. M.; Heslop, D.; Ronge, T.; Conway, C.; Leonard, G.; Townsend, D.; Tiedemann, R.; Lamy, F.; Calvert, A. T.

    2014-12-01

    Geomagnetic excursions are short-lived deviations of the geomagnetic field from the normal range of secular variation. Despite significant advances in geomagnetic excursion research over the past 20 years, fundamental questions remain concerning the typical duration and global morphology of excursional geomagnetic fields. To answer such questions, more high-resolution, chronologically well-constrained excursion records are required, particularly from the Southern Hemisphere. We present preliminary paleomagnetic records of the Laschamp (~41 ka) and Mono Lake (~35 ka) excursions from three marine sediment cores from the Bounty Trough, New Zealand margin, and complementary volcanic records of the Laschamp excursion from lavas of Mt Ruapehu, New Zealand. Relatively high sedimentation rates of 12 - 26 cm/kyr in the Bounty Trough during glacial periods allow identification of excursional field behavior at each of the studied core locations. Each core displays one or two excursional events, with rapid directional swings between stable normal polarity and reversed excursional directions, each associated with coincident relative paleointensity minima. These anomalous paleomagnetic directions are interpreted to represent the Laschamp and Mono Lake excursions, based on a combination of tephrochronology, radiocarbon dating, and cyclostratigraphy (defined from core-scanning X-ray fluorescence and magnetic susceptibility records). Beside these records, we present results from fourteen lava flows, on Mt Ruapehu, for which 40Ar-39Ar dating indicates ages of between 39 and 45 ka. The step heating 40Ar-39Ar experiments produced particularly flat age plateaus, with corresponding 2 s.d. errors mostly approaching 1 kyr. The youngest and oldest flows carry normal polarity magnetization, however six flows, dated between 41 and 43 ka, display transitional field characteristics. Three of these flows display a declination swing of around 180o, which coincides with a previously published

  12. Statistical analysis of simulation-generated time series : Systolic vs. semi-systolic correlation on the Connection Machine

    NARCIS (Netherlands)

    Dontje, T.; Lippert, Th.; Petkov, N.; Schilling, K.

    1992-01-01

    Autocorrelation becomes an increasingly important tool to verify improvements in the state of the simulational art in Latice Gauge Theory. Semi-systolic and full-systolic algorithms are presented which are intensively used for correlation computations on the Connection Machine CM-2. The

  13. Cross plane scattering correction

    International Nuclear Information System (INIS)

    Shao, L.; Karp, J.S.

    1990-01-01

    Most previous scattering correction techniques for PET are based on assumptions made for a single transaxial plane and are independent of axial variations. These techniques will incorrectly estimate the scattering fraction for volumetric PET imaging systems since they do not take the cross-plane scattering into account. In this paper, the authors propose a new point source scattering deconvolution method (2-D). The cross-plane scattering is incorporated into the algorithm by modeling a scattering point source function. In the model, the scattering dependence both on axial and transaxial directions is reflected in the exponential fitting parameters and these parameters are directly estimated from a limited number of measured point response functions. The authors' results comparing the standard in-plane point source deconvolution to the authors' cross-plane source deconvolution show that for a small source, the former technique overestimates the scatter fraction in the plane of the source and underestimate the scatter fraction in adjacent planes. In addition, the authors also propose a simple approximation technique for deconvolution

  14. An excursion through elementary mathematics, volume ii euclidean geometry

    CERN Document Server

    Caminha Muniz Neto, Antonio

    2018-01-01

    This book provides a comprehensive, in-depth overview of elementary mathematics as explored in Mathematical Olympiads around the world. It expands on topics usually encountered in high school and could even be used as preparation for a first-semester undergraduate course. This second volume covers Plane Geometry, Trigonometry, Space Geometry, Vectors in the Plane, Solids and much more. As part of a collection, the book differs from other publications in this field by not being a mere selection of questions or a set of tips and tricks that applies to specific problems. It starts from the most basic theoretical principles, without being either too general or too axiomatic. Examples and problems are discussed only if they are helpful as applications of the theory. Propositions are proved in detail and subsequently applied to Olympic problems or to other problems at the Olympic level. The book also explores some of the hardest problems presented at National and International Mathematics Olympiads, as well as many...

  15. Fourier plane imaging microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Dominguez, Daniel, E-mail: daniel.dominguez@ttu.edu; Peralta, Luis Grave de [Department of Physics, Texas Tech University, Lubbock, Texas 79409 (United States); Nano Tech Center, Texas Tech University, Lubbock, Texas 79409 (United States); Alharbi, Nouf; Alhusain, Mdhaoui [Department of Physics, Texas Tech University, Lubbock, Texas 79409 (United States); Bernussi, Ayrton A. [Nano Tech Center, Texas Tech University, Lubbock, Texas 79409 (United States); Department of Electrical and Computer Engineering, Texas Tech University, Lubbock, Texas 79409 (United States)

    2014-09-14

    We show how the image of an unresolved photonic crystal can be reconstructed using a single Fourier plane (FP) image obtained with a second camera that was added to a traditional compound microscope. We discuss how Fourier plane imaging microscopy is an application of a remarkable property of the obtained FP images: they contain more information about the photonic crystals than the images recorded by the camera commonly placed at the real plane of the microscope. We argue that the experimental results support the hypothesis that surface waves, contributing to enhanced resolution abilities, were optically excited in the studied photonic crystals.

  16. Defibrillator Implantation in Patients with Nonischemic Systolic Heart Failure

    DEFF Research Database (Denmark)

    Køber, Lars; Thune, Jens J; Nielsen, Jens C

    2016-01-01

    Background The benefit of an implantable cardioverter-defibrillator (ICD) in patients with symptomatic systolic heart failure caused by coronary artery disease has been well documented. However, the evidence for a benefit of prophylactic ICDs in patients with systolic heart failure that is not due...... to coronary artery disease has been based primarily on subgroup analyses. The management of heart failure has improved since the landmark ICD trials, and many patients now receive cardiac resynchronization therapy (CRT). Methods In a randomized, controlled trial, 556 patients with symptomatic systolic heart.......6%) in the control group (P=0.29). Conclusions In this trial, prophylactic ICD implantation in patients with symptomatic systolic heart failure not caused by coronary artery disease was not associated with a significantly lower long-term rate of death from any cause than was usual clinical care. (Funded by Medtronic...

  17. Risk following hospitalization in stable chronic systolic heart failure

    DEFF Research Database (Denmark)

    Abrahamsson, Putte; Swedberg, Karl; Borer, Jeffrey S

    2013-01-01

    We explored the impact of being hospitalized due to worsening heart failure (WHF) or a myocardial infarction (MI) on subsequent mortality in a large contemporary data set of patients with stable chronic systolic heart failure (HF).......We explored the impact of being hospitalized due to worsening heart failure (WHF) or a myocardial infarction (MI) on subsequent mortality in a large contemporary data set of patients with stable chronic systolic heart failure (HF)....

  18. Instabilities of Kirkendall planes

    NARCIS (Netherlands)

    Dal, van M.J.H.; Gusak, A.M.; Cserhati, C.; Kodentsov, A.; Loo, van F.J.J.

    2001-01-01

    Reconsideration of the Kirkendall effect is presented. It is demonstrated (experimentally as well as theoretically) that Kirkendall planes can be multiple, stable or unstable within a single-phase reaction zone. A general criterion of instabilty is given.

  19. Comparison of clinical utility between diaphragm excursion and thickening change using ultrasonography to predict extubation success

    Science.gov (United States)

    Yoo, Jung-Wan; Lee, Seung Jun; Lee, Jong Deog; Kim, Ho Cheol

    2018-01-01

    Background/Aims Both diaphragmatic excursion and change in muscle thickening are measured using ultrasonography (US) to assess diaphragm function and mechanical ventilation weaning outcomes. However, which parameter can better predict successful extubation remains to be determined. The aim of this study was to compare the clinical utility of these two diaphragmatic parameters to predict extubation success. Methods This study included patients subjected to extubation trial in the medical or surgical intensive care unit of a university-affiliated hospital from May 2015 through February 2016. Diaphragm excursion and percent of thickening change (Δtdi%) were measured using US within 24 hours before extubation. Results Sixty patients were included, and 78.3% (47/60) of these patients were successfully extubated, whereas 21.7% (13/60) were not. The median degree of excursion was greater in patients with extubation success than in those with extubation failure (1.65 cm vs. 0.8 cm, p success had a greater Δtdi% than those with extubation failure (42.1% vs. 22.5%, p = 0.03). The areas under the receiver operating curve for excursion and Δtdi% were 0.836 (95% confidence interval [CI], 0.717 to 0.919) and 0.698 (95% CI, 0.566 to 0.810), respectively (p = 0.017). Conclusions Diaphragm excursion seems more accurate than a change in the diaphragm thickness to predict extubation success. PMID:29050461

  20. Algebraic Structures on MOD Planes

    OpenAIRE

    Kandasamy, Vasantha; Ilanthenral, K.; Smarandache, Florentin

    2015-01-01

    Study of MOD planes happens to a very recent one. In this book, systematically algebraic structures on MOD planes like, MOD semigroups, MOD groups and MOD rings of different types are defined and studied. Such study is innovative for a large four quadrant planes are made into a small MOD planes. Several distinct features enjoyed by these MOD planes are defined, developed and described.

  1. On the joint distribution of excursion duration and amplitude of a narrow-band Gaussian process

    DEFF Research Database (Denmark)

    Ghane, Mahdi; Gao, Zhen; Blanke, Mogens

    2018-01-01

    of amplitude and period are limited to excursion through a mean-level or to describe the asymptotic behavior of high level excursions. This paper extends the knowledge by presenting a theoretical derivation of probability of wave exceedance amplitude and duration, for a narrow-band Gaussian process......The probability density of crest amplitude and of duration of exceeding a given level are used in many theoretical and practical problems in engineering. The joint density is essential for design of constructions that are subjected to waves and wind. The presently available joint distributions...... distribution, as expected, and that the marginal distribution of excursion duration works both for asymptotic and non-asymptotic cases. The suggested model is found to be a good replacement for the empirical distributions that are widely used. Results from simulations of narrow-band Gaussian processes, real...

  2. Arterial wave reflection and subclinical left ventricular systolic dysfunction.

    Science.gov (United States)

    Russo, Cesare; Jin, Zhezhen; Takei, Yasuyoshi; Hasegawa, Takuya; Koshaka, Shun; Palmieri, Vittorio; Elkind, Mitchell Sv; Homma, Shunichi; Sacco, Ralph L; Di Tullio, Marco R

    2011-03-01

    Increased arterial wave reflection is a predictor of cardiovascular events and has been hypothesized to be a cofactor in the pathophysiology of heart failure. Whether increased wave reflection is inversely associated with left-ventricular (LV) systolic function in individuals without heart failure is not clear. Arterial wave reflection and LV systolic function were assessed in 301 participants from the Cardiovascular Abnormalities and Brain Lesions (CABL) study using two-dimensional echocardiography and applanation tonometry of the radial artery to derive central arterial waveform by a validated transfer function. Aortic augmentation index (AIx) and wasted energy index (WEi) were used as indices of wave reflection. LV systolic function was measured by LV ejection fraction (LVEF) and tissue Doppler imaging (TDI). Mitral annulus peak systolic velocity (Sm), peak longitudinal strain and strain rate were measured. Participants with history of coronary artery disease, atrial fibrillation, LVEF less than 50% or wall motion abnormalities were excluded. Mean age of the study population was 68.3 ± 10.2 years (64.1% women, 65% hypertensive). LV systolic function by TDI was lower with increasing wave reflection, whereas LVEF was not. In multivariate analysis, TDI parameters of LV longitudinal systolic function were significantly and inversely correlated to AIx and WEi (P values from 0.05 to 0.002). In a community cohort without heart failure and with normal LVEF, an increased arterial wave reflection was associated with subclinical reduction in LV systolic function assessed by novel TDI techniques. Further studies are needed to investigate the prognostic implications of this relationship.

  3. Volcanic records of the Laschamp geomagnetic excursion from Mt Ruapehu, New Zealand

    Science.gov (United States)

    Ingham, E.; Turner, G. M.; Conway, C. E.; Heslop, D.; Roberts, A. P.; Leonard, G.; Townsend, D.; Calvert, A.

    2017-08-01

    We present palaeodirectional records of the Laschamp geomagnetic excursion from lavas on Mt Ruapehu, New Zealand. Fourteen lava flows on the northwestern and southern flanks of Mt Ruapehu, with 40Ar/39Ar weighted mean plateau ages that range from 46.3 ± 2.0 to 39.9 ± 1.4 ka, were studied. The youngest and older flows carry a normal polarity magnetization; however, six flows, dated between 46.3 ± 2.0 and 42.7 ± 1.8 ka, record excursional directions. Three of these flows record southerly palaeomagnetic declinations and negative inclinations that agree well with a published Laschamp record from the Auckland Volcanic Field (AVF). Together, the AVF and Mt Ruapehu lavas currently represent the only volcanic records of the Laschamp excursion outside the Chaîne des Puys region, France. Thus, they make an important contribution to the global set of Laschamp excursion records. Virtual geomagnetic pole (VGP) groups for the New Zealand and French records early in the excursion are compatible with a dipole-dominated field that rotated to an equatorial orientation while simultaneously decaying in strength. In contrast, younger excursional flows from France and New Zealand yield separate VGP groups, which suggest either that the field had a nondipolar morphology in this later phase, or that the VGP groups were not synchronous. 40Ar/39Ar ages for the Mt Ruapehu record are on average slightly older than published northern hemisphere ages and from the relative palaeointensity minimum in the GLOPIS sedimentary stack. Although few individual ages differ significantly at the 2σ level, the spread suggests an overall excursion duration that is longer than the currently accepted 1500 years. This age spread may result from excess Ar in magmas at the time of the eruption biasing the results to slightly older ages, or from non-synchronous excursional field behaviour at near-antipodal locations, or, possibly, a precursory phase prior to the main excursion.

  4. FELIX - a computer code for simulation of criticality excursions in liquid fissile solutions

    International Nuclear Information System (INIS)

    Gmal, B.; Weber, J.

    1989-01-01

    Knowledge of characteristic parameters like evolved power fission yield during an accidental excursion is of essential importance to estimate possible radiological consequences and resulting safety hazards. The computer code 'FELIX' simulates excursion characteristics of aqueous critical assemblies: Starting out from given initial conditions the space-dependent neutron kinetic equations are solved in one-dimensional geometry. Power, fission yield, reactivity and temperature are calculated as a function of time. Reactivity-feedback includes density effects and radiolytic gas voids. Results from calculations are compared with CRAC-experiments. (orig.)

  5. The Hirnantian δ13C Positive Excursion in the Nabiullino Section (South Urals)

    Science.gov (United States)

    Yakupov, R. R.; Mavrinskaya, T. M.; Smoleva, I. V.

    2018-02-01

    The upper Sandbian, Katian, and Hirnantian complexes of conodonts in the upper Ordovician section of the western slope of the Southern Urals near the village of Nabiullino were studied. The δ13C positive excursion with a maximum of 3.3‰ associated with the global Hirnantian isotopic event, HICE, was fixed for the first time. This excursion shows the beginning of the Hirnantian stage in the terrigenous-carbonate section of the upper Ordovician in the Southern Urals. It coincides with the first occurrence of the Hirnantian conodont species of Gamachignathus ensifer and the conodonts of shallow-water biophacies, Aphelognathus-Ozarkodina, reflecting the global glacio-eustatic event.

  6. Transformational plane geometry

    CERN Document Server

    Umble, Ronald N

    2014-01-01

    Axioms of Euclidean Plane Geometry The Existence and Incidence Postulates The Distance and Ruler Postulates The Plane Separation Postulate The Protractor Postulate The Side-Angle-Side Postulate and the Euclidean Parallel Postulate Theorems of Euclidean Plane Geometry The Exterior Angle Theorem Triangle Congruence Theorems The Alternate Interior Angles Theorem and the Angle Sum Theorem Similar Triangles Introduction to Transformations, Isometries, and Similarities Transformations Isometries and SimilaritiesAppendix: Proof of Surjectivity Translations, Rotations, and Reflections Translations Rotations Reflections Appendix: Geometer's Sketchpad Commands Required by Exploratory Activities Compositions of Translations, Rotations, and Reflections The Three Points Theorem Rotations as Compositions of Two Reflections Translations as Compositions of Two Halfturns or Two Reflections The Angle Addition Theorem Glide Reflections Classification of Isometries The Fundamental Theorem and Congruence Classification of Isometr...

  7. Fast Plane Wave Imaging

    DEFF Research Database (Denmark)

    Jensen, Jonas

    This PhD project investigates and further develops methods for ultrasound plane wave imaging and blood flow estimation with the objective of overcoming some of the major limitations in conventional ultrasound systems, which are related to low frame rates and only estimation of velocities along...... the ultrasound beam. The first part of the contribution investigates the compromise between frame rate and plane wave image quality including the influence of grating lobes from a λ-pitch transducer. A method for optimizing the image quality is suggested, and it is shown that the frame rate can be increased...... healthy volunteers. Complex flow patterns were measured in an anthropomorphic flow phantom and showed good agreement with the velocity field simulated using computational fluid dynamics. The last part of the contribution investigates two clinical applications. Plane wave imaging was used for slow velocity...

  8. The OBS control plane

    DEFF Research Database (Denmark)

    Manolova, Anna Vasileva; Ruepp, Sarah Renée

    2010-01-01

    . The applicability analysis carried out here focuses on the actual feasibility of the integration and the potential trade-offs which appear when two contradicting principles are combined. Taking advantage of the flexibility of the GMPLS control plane does not seem to be as easy and as straightforward as expected...

  9. Low Power Systolic Array Based Digital Filter for DSP Applications

    Directory of Open Access Journals (Sweden)

    S. Karthick

    2015-01-01

    Full Text Available Main concepts in DSP include filtering, averaging, modulating, and correlating the signals in digital form to estimate characteristic parameter of a signal into a desirable form. This paper presents a brief concept of low power datapath impact for Digital Signal Processing (DSP based biomedical application. Systolic array based digital filter used in signal processing of electrocardiogram analysis is presented with datapath architectural innovations in low power consumption perspective. Implementation was done with ASIC design methodology using TSMC 65 nm technological library node. The proposed systolic array filter has reduced leakage power up to 8.5% than the existing filter architectures.

  10. Dairy consumption, systolic blood pressure, and risk of hypertension

    DEFF Research Database (Denmark)

    Ding, Ming; Huang, Tao; Bergholdt, Helle Km

    2017-01-01

    Objective To examine whether previous observed inverse associations of dairy intake with systolic blood pressure and risk of hypertension were causal.Design Mendelian randomization study using the single nucleotide polymorphism rs4988235 related to lactase persistence as an instrumental variable...... blood pressure but not risk of hypertension (odds ratio 0.98, 0.97 to 1.00; P=0.11).Conclusion The weak inverse association between dairy intake and systolic blood pressure in observational studies was not supported by a comprehensive instrumental variable analysis and systematic review of existing...

  11. A one night stand? Reproductive excursions of female roe deer as a breeding dispersal tactic

    Czech Academy of Sciences Publication Activity Database

    Debeffe, L.; Focardi, S.; Bonenfant, Ch.; Hewison, A. J. M.; Morellet, N.; Vanpé, C.; Heurich, M.; Kjellander, P.; Linnell, J. D. C.; Mysterud, A.; Pellerin, M.; Šustr, Pavel; Urbano, F.; Cagnacci, F.

    2014-01-01

    Roč. 176, č. 2 (2014), s. 431-443 ISSN 0029-8549 Institutional support: RVO:67179843 Keywords : Mate choice * Inbreeding avoidance * GPS telemetry * Rut excursion * Ungulate Subject RIV: EH - Ecology, Behaviour Impact factor: 3.093, year: 2014

  12. Multicultural Group Work on Field Excursions to Promote Student Teachers' Intercultural Competence

    Science.gov (United States)

    Brendel, Nina; Aksit, Fisun; Aksit, Selahattin; Schrüfer, Gabriele

    2016-01-01

    As a response to the intercultural challenges of Geography Education, this study seeks to determine factors fostering intercultural competence of student teachers. Based on a one-week multicultural field excursion of eight German and eight Turkish students in Kayseri (Turkey) on Education for Sustainable Development, we used qualitative interviews…

  13. Study of thermal and hydraulic phenomena accompanying a rapid power excursion on a heating channel

    International Nuclear Information System (INIS)

    Nyer, M.

    1989-01-01

    This document provides a study of power excursion phenomena and is divided into five sections. In the first chapter a summary of the principal research conducted world-wide on the thermal and hydrodynamic aspects of power excursions actualized either in the reactors or on installations outside of the pile is provided. In a second chapter, on the basis of the bibliographic study conducted previously, the characteristics and performance that an installation capable of correctly simulating a power excursion are indicated and the experimental device designed and developed is described with emphasis on the measurement methods used. In the third chapter the principal experimental results obtained, as well as their physical interpretation, are given. In the fourth chapter a simplified theoretical model that makes it possible to determine the manner of variation of the phenomena observed during our experiments is proposed, and in the fifth chapter what our study has added to the understanding of the phenomena that arise during a power excursion and the direction that the research should be continued is discussed. 38 refs., 69 figs

  14. Enabling the Development of Student Teacher Professional Identity through Vicarious Learning during an Educational Excursion

    Science.gov (United States)

    Steenekamp, Karen; van der Merwe, Martyn; Mehmedova, Aygul Salieva

    2018-01-01

    This paper explores the views of student teachers who were provided vicarious learning opportunities during an educational excursion, and how the learning enabled them to develop their teacher professional identity. This qualitative research study, using a social-constructivist lens highlights how vicarious learning influenced student teachers'…

  15. Traverse across the Nelspruit batholith and the geology of the excursion route between Sabie and Witbank

    International Nuclear Information System (INIS)

    Robb, L.J.; Anhaeusser, C.R.

    1981-01-01

    A geologic survey was done on the traverse across the Nelspruit batholith and the geology of the excursion route between Sabie and Witbank. Rubidium isotopes, strontium 86 and strontium 87 were used to determine the rock age. The petrogenetic aspects relating to the Nelspruit batholith were also studied

  16. Excursions in the catazonal rock complexes of the polyorogenic terrain of Cabo Ortegal (NW Spain)

    NARCIS (Netherlands)

    Vogel, D.E.

    1967-01-01

    This excursion program anticipates the publication of a PhD. thesis (Vogel, in preparation) in this periodical and is intended as a guide to those points at Cabo Ortegal, that are readily accessible, well exposed and of general petrological interest. The described localities are indicated on a small

  17. The impact of feedwater and condensate return excursions on boiler system component failures

    Energy Technology Data Exchange (ETDEWEB)

    Esmacher, Mel J. [GE Water and Process Technologies, The Woodlands, TX (United States); Rossi, Anthony [GE Water and Process Technologies, Trevose, PA (United States)

    2010-02-15

    During boiler operation, the transport of contaminants in boiler feedwater or condensate return via hardness excursions or transport of metal oxides due to corrosion can cause fouling and subsequent tube failure due to under-deposit corrosion or overheating. Case histories are reviewed and suitable corrective actions discussed. (orig.)

  18. Glucose and triglyceride excursions following a standardized meal in individuals with diabetes: ELSA-Brasil study.

    Science.gov (United States)

    Riboldi, Bárbara P; Luft, Vivian C; de Castilhos, Cristina D; de Cardoso, Letícia O; Schmidt, Maria I; Barreto, Sandhi M; de Sander, Maria F; Alvim, Sheila M; Duncan, Bruce B

    2015-02-13

    To assess glucose and triglyceride excursions 2 hours after the ingestion of a standardized meal and their associations with clinical characteristics and cardiovascular complications in individuals with diabetes. Blood samples of 898 subjects with diabetes were collected at fasting and 2 hours after a meal containing 455 kcal, 14 g of saturated fat and 47 g of carbohydrates. Self-reported morbidity, socio-demographic characteristics and clinical measures were obtained by interview and exams performed at the baseline visit of the ELSA-Brasil cohort study. Median (interquartile range, IQR) for fasting glucose was 150.5 (123-198) mg/dL and for fasting triglycerides 140 (103-199) mg/dL. The median excursion for glucose was 45 (15-76) mg/dL and for triglycerides 26 (11-45) mg/dL. In multiple linear regression, a greater glucose excursion was associated with higher glycated hemoglobin (10.7, 95% CI 9.1-12.3 mg/dL), duration of diabetes (4.5; 2.6-6.4 mg/dL, per 5 year increase), insulin use (44.4; 31.7-57.1 mg/dL), and age (6.1; 2.5-9.6 mg/dL, per 10 year increase); and with lower body mass index (-5.6; -8.4- -2.8 mg/dL, per 5 kg/m2 increase). In adjusted logistic regression models, a greater glucose excursion was marginally associated with the presence of cardiovascular comorbidities (coronary heart disease, myocardial infarction and angina) in those with obesity. A greater postprandial glycemic response to a small meal was positively associated with indicators of a decreased capacity for insulin secretion and negatively associated with obesity. No pattern of response was observed with a greater postprandial triglyceride excursion.

  19. The range of excursion of flexor tendons in Zone V: a comparison of active vs passive flexion mobilisation regimes.

    LENUS (Irish Health Repository)

    Panchal, J

    1997-10-01

    A number of early postoperative mobilisation regimes have been developed in an attempt to increase tendon excursion and gliding and thereby reduce formation of adhesions following repair of flexor tendons. Early active flexion mobilisation regimes are becoming more popular, and have replaced early passive flexion regimes in many centres. The aim of the present study was: (a) to determine the range of excursion of flexor tendons in Zone V, and (b) to compare the excursion ranges between active (Belfast) and passive (modified Duran) flexion mobilisation regimes postoperatively. This was done (a) in two cadavers, and (b) in two patients intraoperatively, and postoperatively at 10 days, 3 weeks and 6 weeks. With passive flexion, the mean tendon excursion in Zone V in cadavers was 1 mm for flexor digitorum superficialis (FDS), flexor digitorum profundus (FDP) and flexor pollicis longus (FPL) tendons respectively. With simulated active flexion, the mean tendon excursion was 14 mm, 10 mm and 11 mm respectively. The mean tendon excursion in clinical cases intraoperatively following passive flexion was 2 mm for FDS, FDP and FPL respectively; following simulated active flexion it was 10 mm, 11 mm and 11 mm for FDS, FDP and FPL respectively. On the tenth day following repair, the mean excursions of FDS, FDP and FPL were 1 mm, 4 mm and 4 mm on passive flexion as compared to 3 mm, 10 mm and 12 mm on active flexion respectively. Three weeks postoperatively, the mean excursions of FDS, FDP and FPL tendons were 1 mm, 2 mm and 1 mm on passive flexion as compared to 5 mm, 15 mm on active flexion respectively. Six weeks postoperatively, the mean excursions of FDS, FDP and FPL tendons were 9 mm, 7 mm and 4 mm on passive flexion as compared to 12 mm, 33 mm and 20 mm on active flexion respectively. These results demonstrate an increased excursion of repaired flexor tendons in Zone V following an active flexion mobilisation regime as compared to a passive flexion mobilisation regime.

  20. Left ventricular systolic function in sickle cell anaemia: an ...

    African Journals Online (AJOL)

    Keywords: Left ventricular systolic function, sickle cell anaemia, echocardiographic evaluation, adult Nigerian patients. ..... Quadratic .505. -0.390. 12.231. 8.587 .001*. Cubic .510. -0.180. 8.264. 8.619 .001*. This relationship was further evaluated by means of scat- ter plots and subsequently by regression analysis. The.

  1. Observation of the pulse oximeter trace to estimate systolic blood ...

    African Journals Online (AJOL)

    Southern African Journal of Anaesthesia and Analgesia is co-published by Medpharm .... a clinically relevant amount of time when compared with NIBP ... at the time of recruitment to the study. ... Inclusion criteria were age > 18 years, ASA Class 1 to 3 and .... measured systolic blood pressure values (mean [SD], mmHg) per.

  2. Observation of the pulse oximeter trace to estimate systolic blood ...

    African Journals Online (AJOL)

    Background: The estimation of systolic blood pressure by disappearance and reappearance of the pulse oximeter trace during cuff inflation and deflation was compared with non-invasive blood pressure (NIBP) measurement, across the range of body mass index (BMI), during spinal anaesthesia for Caesarean section.

  3. Characterizations and computational complexity of systolic trellis automata

    Energy Technology Data Exchange (ETDEWEB)

    Ibarra, O H; Kim, S M

    1984-03-01

    Systolic trellis automata are simple models for VLSI. The authors characterize the computing power of these models in terms of turing machines. The characterizations are useful in proving new results as well as giving simpler proofs of known results. They also derive lower and upper bounds on the computational complexity of the models. 18 references.

  4. Euglycemic clamp insulin sensitivity and longitudinal systolic blood pressure

    DEFF Research Database (Denmark)

    Petrie, John R; Malik, Muhammad Omar; Balkau, Beverley

    2013-01-01

    and Cardiovascular disease (RISC) study, we measured insulin sensitivity (M/I) using the euglycemic clamp technique in 1073 healthy European adults (587 women, 486 men) aged 30 to 60 years followed up 3 years later. Systolic BP (SBP) at baseline was higher in insulin-resistant women (ie, those in the low sex...

  5. BKP plane partitions

    International Nuclear Information System (INIS)

    Foda, Omar; Wheeler, Michael

    2007-01-01

    Using BKP neutral fermions, we derive a product expression for the generating function of volume-weighted plane partitions that satisfy two conditions. If we call a set of adjacent equal height-h columns, h > 0, an h-path, then 1. Every h-path can assume one of two possible colours. 2. There is a unique way to move along an h-path from any column to another

  6. BKP plane partitions

    Energy Technology Data Exchange (ETDEWEB)

    Foda, Omar; Wheeler, Michael [Department of Mathematics and Statistics, University of Melbourne, Parkville, Victoria 3010 (Australia)

    2007-01-15

    Using BKP neutral fermions, we derive a product expression for the generating function of volume-weighted plane partitions that satisfy two conditions. If we call a set of adjacent equal height-h columns, h > 0, an h-path, then 1. Every h-path can assume one of two possible colours. 2. There is a unique way to move along an h-path from any column to another.

  7. Carbon nanotube plane fastener

    Directory of Open Access Journals (Sweden)

    Kaori Hirahara

    2011-12-01

    Full Text Available We report a feature of carbon nanotubes (CNTs that arises when the surfaces of two vertically-aligned CNT brushes are pressed together. Adhesion between the CNTs creates a plane fastener-like device. Observations from scanning electron microscopy and measurements of adhesion properties indicate a device-dependence on CNT density and shape near the tip region. Among other applications, such fasteners have the potential to attach small components onto micron-sized electronic devices.

  8. Conquest of the Plane

    OpenAIRE

    Colignatus, Thomas

    2011-01-01

    CONQUEST OF THE PLANE provides: an integrated course for geometry and analysis a didactic build-up that avoids traditional clutter use of only the essentials for good understanding proper place for vectors, complex numbers, linear algebra and trigonometry an original and elegant development of trigonometry an original and elegant foundation for calculus examples from physics, economics and statistics integration within the dynamic environment of Mathematica ...

  9. An Algorithm for constructing Hjelmslev planes

    OpenAIRE

    Hall, Joanne L.; Rao, Asha

    2013-01-01

    Projective Hjelmslev planes and Affine Hjelmselv planes are generalisations of projective planes and affine planes. We present an algorithm for constructing a projective Hjelmslev planes and affine Hjelsmelv planes using projective planes, affine planes and orthogonal arrays. We show that all 2-uniform projective Hjelmslev planes, and all 2-uniform affine Hjelsmelv planes can be constructed in this way. As a corollary it is shown that all 2-uniform Affine Hjelmselv planes are sub-geometries o...

  10. Simultaneous orthogonal plane imaging.

    Science.gov (United States)

    Mickevicius, Nikolai J; Paulson, Eric S

    2017-11-01

    Intrafraction motion can result in a smearing of planned external beam radiation therapy dose distributions, resulting in an uncertainty in dose actually deposited in tissue. The purpose of this paper is to present a pulse sequence that is capable of imaging a moving target at a high frame rate in two orthogonal planes simultaneously for MR-guided radiotherapy. By balancing the zero gradient moment on all axes, slices in two orthogonal planes may be spatially encoded simultaneously. The orthogonal slice groups may be acquired with equal or nonequal echo times. A Cartesian spoiled gradient echo simultaneous orthogonal plane imaging (SOPI) sequence was tested in phantom and in vivo. Multiplexed SOPI acquisitions were performed in which two parallel slices were imaged along two orthogonal axes simultaneously. An autocalibrating phase-constrained 2D-SENSE-GRAPPA (generalized autocalibrating partially parallel acquisition) algorithm was implemented to reconstruct the multiplexed data. SOPI images without intraslice motion artifacts were reconstructed at a maximum frame rate of 8.16 Hz. The 2D-SENSE-GRAPPA reconstruction separated the parallel slices aliased along each orthogonal axis. The high spatiotemporal resolution provided by SOPI has the potential to be beneficial for intrafraction motion management during MR-guided radiation therapy or other MRI-guided interventions. Magn Reson Med 78:1700-1710, 2017. © 2016 International Society for Magnetic Resonance in Medicine. © 2016 International Society for Magnetic Resonance in Medicine.

  11. Automatic noninvasive measurement of systolic blood pressure using photoplethysmography

    Directory of Open Access Journals (Sweden)

    Glik Zehava

    2009-10-01

    Full Text Available Abstract Background Automatic measurement of arterial blood pressure is important, but the available commercial automatic blood pressure meters, mostly based on oscillometry, are of low accuracy. Methods In this study, we present a cuff-based technique for automatic measurement of systolic blood pressure, based on photoplethysmographic signals measured simultaneously in fingers of both hands. After inflating the pressure cuff to a level above systolic blood pressure in a relatively slow rate, it is slowly deflated. The cuff pressure for which the photoplethysmographic signal reappeared during the deflation of the pressure-cuff was taken as the systolic blood pressure. The algorithm for the detection of the photoplethysmographic signal involves: (1 determination of the time-segments in which the photoplethysmographic signal distal to the cuff is expected to appear, utilizing the photoplethysmographic signal in the free hand, and (2 discrimination between random fluctuations and photoplethysmographic pattern. The detected pulses in the time-segments were identified as photoplethysmographic pulses if they met two criteria, based on the pulse waveform and on the correlation between the signal in each segment and the signal in the two neighboring segments. Results Comparison of the photoplethysmographic-based automatic technique to sphygmomanometry, the reference standard, shows that the standard deviation of their differences was 3.7 mmHg. For subjects with systolic blood pressure above 130 mmHg the standard deviation was even lower, 2.9 mmHg. These values are much lower than the 8 mmHg value imposed by AAMI standard for automatic blood pressure meters. Conclusion The photoplethysmographic-based technique for automatic measurement of systolic blood pressure, and the algorithm which was presented in this study, seems to be accurate.

  12. Vacuum immobilisation reduces tumour excursion and minimises intrafraction error in a cohort study of stereotactic ablative body radiotherapy for pulmonary metastases

    International Nuclear Information System (INIS)

    Siva, Shankar; Devereux, Tomas; Kron, Tomas

    2014-01-01

    The purpose of this study is to assess the impact of a vacuum immobilisation system on reproducibility of patient set-up, interfraction stability and tumour motion amplitude. From February 2010 to February 2012 as part of a prospective clinical trial 12 patients with solitary pulmonary metastases had consecutive four-dimensional computed tomography (4DCT) scans performed with and without vacuum immobilisation. The displacement of the tumour centroid position was recorded in each of the 10 phases of the 4DCT reconstruction. A further six patients with seven metastases underwent single fraction stereotactic ablative body radiotherapy (SABR) during this period (a total of 19 targets) and were included in an analysis of positional reproducibility and intrafraction immobilisation. Couch shifts recorded in the medio-lateral (X), cranio-caudal (Y) and ventero-dorsal (Z) planes. For the 19 treatments delivered, the median (0–90% range) shift required immediately pretreatment was 1mm (0–3) in the X-plane, 2mm (0–6) in the Y-plane and 4mm (0–8) in the Z-plane, respectively. The mean (+/− standard deviation) of mid-treatment shifts were 0.3mm (+/− 0.7), 1.1mm (+/− 2) and 0.8mm (+/− 1.5) in the X, Y and Z planes, respectively. Mid-treatment shifts were <2mm in all directions (P=<0.001). The length of treatment time correlated to the required shifts in the Z plane (r2=0.377, P=0.005), but not in the X or Y planes (P=0.198 and P=0.653, respectively). In the subset of 12 patients who had two 4DCTs, the median (range) amplitude of tumour displacements in the X, Y and Z planes when immobilised were 0.9mm (0.3–2.9), 2.6mm (0.2–10.6) and 1.6mm (0.5–5.5), respectively. Immobilisation reduced the volume of tumour displacement during respiration by a median of 52.6% (P=0.021). Vacuum immobilisation reduces total tumour excursion, facilitates reproducible positioning and provides robust intrafractional immobilisation during SABR treatments for pulmonary metastases.

  13. Association of left ventricular longitudinal and circumferential systolic dysfunction with diastolic function in hypertension: a nonlinear analysis focused on the interplay with left ventricular geometry.

    Science.gov (United States)

    Ballo, Piercarlo; Nistri, Stefano; Cameli, Matteo; Papesso, Barbara; Dini, Frank Lloyd; Galderisi, Maurizio; Zuppiroli, Alfredo; Mondillo, Sergio

    2014-02-01

    The relationships of left ventricular (LV) longitudinal and circumferential systolic dysfunction with diastolic performance in hypertensive patients have never been compared. In 532 asymptomatic hypertensive patients, circumferential function was assessed with the use of midwall fractional shortening (mFS) and stress-corrected mFS (SCmFS), whereas longitudinal function was assessed with the use of left atrioventricular plane displacement (AVPD) and systolic mitral annulus velocity (s'). Early diastolic annular velocity (e') and the E/e' ratio were measured. Global longitudinal and circumferential strain were determined in a subset of 210 patients. e' was linearly related to all systolic indexes (AVPD: R = 0.40; s': R = 0.39; mFS: R = 0.16; SCmFS: R = 0.17; all P SCmFS. Longitudinal indexes were superior to circumferential ones in predicting e' <8 cm/s, E/e' <8, and E/e' ≥13. The effect of LV geometry on LV diastolic function was evident among patients with preserved systolic longitudinal function, but was blunted among patients with impaired longitudinal function. In multivariable analyses, only longitudinal indexes remained associated with e' and E/e'. Analyses using strains provided similar results. In asymptomatic hypertensive subjects, LV diastolic performance is independently associated with longitudinal systolic dysfunction, but not with circumferential systolic dysfunction. Subtle longitudinal systolic impairment plays a role in mediating the effect of LV geometry on diastolic performance. These findings may support the need of critically revising the concept of isolated diastolic dysfunction in these patients. Copyright © 2014 Elsevier Inc. All rights reserved.

  14. Peak systolic pressure-volume relationships in man

    International Nuclear Information System (INIS)

    Adachi, Haruhiko; Sugihara, Hiroki; Nakagawa, Hiroaki; Katsume, Hiroshi; Ochiai, Masakazu; Ijichi, Hamao

    1985-01-01

    We determined the relationship between left ventricular (LV) peak systolic pressure (PSP) and end-systolic volume, non-invasively using cuff sphygmomanometry and radionuclide angiocardiography (RNA). Systolic blood pressure (SBP) measured in the arm was substituted for PSP. LV enddiastolic volume (EDV), end-systolic volume (ESV) and ejection fraction (EF) were determined by a non-geometric method of gated RNA and recorded in three different hemodynamic states: at rest (basal state), during increased SBP after angiotensin administration (initial dose, 1-2 μg/min) and during decreased SBP after nitrate (sublingual nitroglycerin, 0.3-0.6 mg, or intravenous isosorbide dinitrate, 0.5-1.0 mg/min). The reproducibility of this method, tested in six subjects, proved to be good. Fifty-five subjects were divided into four groups based on EF at rest. The EDV and ESV were increased by angiotensin, and decreased by nitrate in all groups. EF was decreased by angiotensin and increased by nitrate. In contrast, the changes in PSP/ESVI due to these drugs remained in a narrow range in all groups. The regression lines of the PSP/ESVI relationship were almost linear and were steeper in the group with higher EF. Esub(max), the slope of the lines, was 5.75 +- 3.48 mmHg/ml/m 2 in group 1 (EF>50%), 3.16 +- 1.83 mmHg/ml/m 2 in group 2 (EF 49-40%), 2.27 +- 0.86 mmHg/ml/m 2 in group 3 (EF 39-30%) and 0.59 +- 0.50 mmHg/ml/m 2 in group 4 (EF<29%). The theoretical volume at zero pressure (VoI) did not meet in a definite value and was not related to EF at rest. Thus, the left ventricular peak systolic pressure-end-systolic volume relationship can be assessed non-invasively from radionuclide angiocardiography, which can be widely used for the evaluation of ventricular contractility, even in patients with asynergic ventricular contraction for whom echocardiography is unsuitable in measuring ventricular volume. (author)

  15. Plane partition vesicles

    International Nuclear Information System (INIS)

    Rensburg, E J Janse van; Ma, J

    2006-01-01

    We examine partitions and their natural three-dimensional generalizations, plane partitions, as models of vesicles undergoing an inflation-deflation transition. The phase diagrams of these models include a critical point corresponding to an inflation-deflation transition, and exhibits multicritical scaling in the vicinity of a multicritical point located elsewhere on the critical curve. We determine the locations of the multicritical points by analysing the generating functions using analytic and numerical means. In addition, we determine the numerical values of the multicritical scaling exponents associated with the multicritical scaling regimes in these models

  16. A long-term geomagnetic excursion from Plio-Pleistocene sediments in Java

    Science.gov (United States)

    Hyodo, Masayuki; Sunata, Wahyu; Susanto, Eko E.

    1992-06-01

    Duplicate records of a geomagnetic excursion at two sites separated by 200 km in Java, Indonesia, are reported. The existence of a large-scale wing of declination between the Olduvai and Jaramillo event is revealed. The field directions in reverse polarity show a gradual clockwise swing to almost west-pointing directions, followed by a rapid return to south-pointing directions. At both sites, the declinations have maximum deflection more than 70 deg from the axial dipole field direction, and the inclinations remain low during the swing. An upward-pointing eccentric radial dipole model rather than a downward-pointing one seems plausible to explain the geomagnetic behavior during the excursion.

  17. Revealing the Microscopic Real-Space Excursion of a Laser-Driven Electron

    Directory of Open Access Journals (Sweden)

    Heiko G. Kurz

    2016-08-01

    Full Text Available High-order harmonic spectroscopy allows one to extract information on fundamental quantum processes, such as the exit time in the tunneling of an electron through a barrier with attosecond time resolution and molecular structure with angstrom spatial resolution. Here, we study the spatial motion of the electron during high-order harmonic generation in an in situ pump-probe measurement using high-density liquid water droplets as a target. We show that molecules adjacent to the emitting electron-ion pair can disrupt the electron’s trajectory when positioned within the range of the maximum electronic excursion distance. This allows us to use the parent ion and the neighboring molecules as boundaries for the electronic motion to measure the maximum electronic excursion distance during the high-order harmonic generation process. Our analysis of the process is relevant for optimizing high-harmonic yields in dense media.

  18. Report of the excursion Energy from Biomass to Germany, 26-28 November 1997

    International Nuclear Information System (INIS)

    Gigler, J.K.

    1997-12-01

    The aim of the title excursion was to provide participants with up-to-date information of different aspects with respect to the production of energy from biomass. Visits were paid to the main office and the research centre of 'Lurgi Umwelt' in Frankfurt am Main, the cogeneration installation 'Pflanzenoel-Blockheizkraftwerk' in Greussenheim, a local government organization, involved in the management of biomass projects, CARMEN ('Centrales Agrar Rohstoff Marketing und Entwicklungs-Netzwerk' or Central Agricultural Raw Material Marketing and Development Network) in Wuerzburg, the 22 MW biomass heating power plant 'Biomasse-Heizkraftwerk Sulzbach-Rosenberg' in Sulzbach-Rosenberg, and the research institute (in particular with respect to miscanthus) 'Bayerische Landesanstalt fuer Weinbau und Gartenbau' in Wuerzburg. Next to an evaluation of the excursion and an overview of the experiences of the participants background information from the visited sites is presented

  19. Systolic pocessing and an implementation for signal and image processing

    Energy Technology Data Exchange (ETDEWEB)

    Kulkarni, A.V.; Yen, D.W.L.

    1982-10-01

    Many signal and image processing applications impose a severe demand on the I/O bandwidth and computation power of general-purpose computers. The systolic concept offers guidelines in building cost-effective systems that balance I/O with computation. The resulting simplicity and regularity of such systems leads to modular designs suitable for VLSI implementation. The authors describe a linear systolic array capable of evaluating a large class of inner-product functions used in signal and image processing. These include matrix multiplications, multidimensional convolutions using fixed or time-varying kernels, as well as various nonlinear functions of vectors. The system organization of a working prototype is also described. 11 references.

  20. Left Atrial Systolic Force in Asymptomatic Aortic Stenosis

    DEFF Research Database (Denmark)

    Cioffi, Giovanni; Cramariuc, Dana; Dalsgaard, Morten

    2011-01-01

    LASF in the total study population was 21 ± 14 kdynes/cm(2) . The determinants of LASF were higher age, heart rate, body mass index, systolic blood pressure, left ventricular (LV) mass, mitral peak early velocity, maximal LA volume, and longer mitral deceleration time (multiple R(2) = 0.37, P ...Background: There is a limited knowledge about left atrial (LA) systolic force (LASF) and its key determinants in patients with asymptomatic mild-moderate aortic stenosis (AS). Methods: We used baseline clinic and echocardiographic data from 1,566 patients recruited in the simvastatin ezetimibe...... in aortic stenosis study evaluating the effect of placebo-controlled combined simvastatin and ezetimibe treatment in asymptomatic AS. The LASF was calculated by Manning's method. Low and high LASF were defined as 95th percentile of the distribution within the study population, respectively. Results: Mean...

  1. Estimates of the effectiveness of automatic control in alleviating wake vortex induced roll excursions

    Science.gov (United States)

    Tinling, B. E.

    1977-01-01

    Estimates of the effectiveness of a model following type control system in reducing the roll excursion due to a wake vortex encounter were obtained from single degree of freedom computations with inputs derived from the results of wind tunnel, flight, and simulation experiments. The analysis indicates that the control power commanded by the automatic system must be roughly equal to the vortex induced roll acceleration if effective limiting of the maximum bank angle is to be achieved.

  2. The use of genetic programming to develop a predictor of swash excursion on sandy beaches

    OpenAIRE

    M. Passarella; E. B. Goldstein; S. De Muro; G. Coco

    2018-01-01

    We use genetic programming (GP), a type of machine learning (ML) approach, to predict the total and infragravity swash excursion using previously published data sets that have been used extensively in swash prediction studies. Three previously published works with a range of new conditions are added to this data set to extend the range of measured swash conditions. Using this newly compiled data set we demonstrate that a ML approach can reduce the prediction errors compared ...

  3. Cerium anomaly across the mid-Tournaisian carbon isotope excursion (TICE)

    Science.gov (United States)

    Jiang, G.; Morales, D. C.; Maharjan, D. K.

    2015-12-01

    The Early Mississippian (ca. 359-345 Ma) represents one of the most important greenhouse-icehouse climate transitions in Earth history. Closely associated with this critical transition is a prominent positive carbon isotope excursion (δ13C ≥ +5‰) that has been documented from numerous stratigraphic successions across the globe. This δ13C excursion, informally referred to as the TICE (mid-Tournaisian carbon isotope excursion) event, has been interpreted as resulting from enhanced organic carbon burial, with anticipated outcomes including the lowering of atmospheric CO2 and global cooling, the growth of continental ice sheets and sea-level fall, and the increase of ocean oxygenation and ocean redox changes. The casual relationship between these events has been addressed from various perspectives but not yet clearly demonstrated. To document the potential redox change associated with the perturbation of the carbon cycle, we have analyzed rare earth elements (REE) and trace elements across the TICE in two sections across a shallow-to-deep water transect in the southern Great Basin (Utah and Nevada), USA. In both sections, the REE data show a significant positive cerium (Ce) anomaly (Ce/Ce* = Ce/(0.5La+0.5Pr)). Prior to the positive δ13C shift, most Ce/Ce* values are around 0.3 (between 0.2 and 0.4). Across the δ13C peak, Ce/Ce* values increase up to 0.87, followed by a decrease back to 0.2~0.3 after the δ13C excursion (Figure 1). The positive Ce anomaly is best interpreted as recording expansion of oxygen minimum zone and anoxia resulted from increased primary production. This is consistent with a significant increase of nitrogen isotopes (δ15N) across the δ13C peak. Integration of the carbon, nitrogen, and REE data demonstrates a responsive earth systems change linked to the perturbation of the Early Mississippian carbon cycle.

  4. Fuel-steel mixing and radial mesh effects in power excursion simulations

    International Nuclear Information System (INIS)

    Chen, X.-N.; Rineiski, A.; Gabrielli, F.; Andriolo, L.; Vezzoni, B.; Li, R.; Maschek, W.; Kiefhaber, E.

    2016-01-01

    Highlights: • Fuel-steel mixing and radial mesh effects are significant on power excursion. • The earliest power peak is reduced and retarded by these two effects. • Unprotected loss of coolant transients in ESFR core are calculated. - Abstract: This paper deals with SIMMER-III once-through simulations of the earliest power excursion initiated by an unprotected loss of flow (ULOF) in the Working Horse design of the European Sodium Cooled Fast Reactor (ESFR). Since the sodium void effect is strictly positive in this core and dominant in the transient, a power excursion is initiated by sodium boiling in the ULOF case. Two major effects, namely (1) reactivity effects due to fuel-steel mixing after melting and (2) the radial mesh size, which were not considered originally in SIMMER simulations for ESFR, are studied. The first effect concerns the reactivity difference between the heterogeneous fuel/clad/wrapper configuration and the homogeneous mixture of steel and fuel. The full core homogenization (due to melting) effect is −2 $, though a smaller effect takes place in case of partial core melting. The second effect is due to the SIMMER sub-assembly (SA) coarse mesh treatment, where a simultaneous sodium boiling onset in all SAs belonging to one ring leads to an overestimated reactivity ramp. For investigating the influence of fuel/steel mixing effects, a lumped “homogenization” reactivity feedback has been introduced, being proportional to the molten steel mass. For improving the coarse mesh treatment, we employ finer radial meshes to take the subchannel effects into account, where the side and interior channels have different coolant velocities and temperatures. The simulation results show that these two effects have significant impacts on the earliest power excursion after the sodium boiling.

  5. Frequency modulation excursion and rate discrimination in normal-hearing and hearing-impaired listeners

    DEFF Research Database (Denmark)

    Schindwolf, Isabel; Vatti, Marianna; Santurette, Sébastien

    Most natural sounds contain frequency fluctuations over time such as changes in their fundamental frequency, non-periodic speech formant transitions, or periodic fluctuations like musical vibrato. These are sometimes characterized as frequency modulation (FM) with a given excursion (FMe) and rate......, this study investigated the effects of age and SNHL on FMe and FMr difference limens (DLs) for reference values typical of frequency fluctuations observed in speech and music signals....

  6. Glucose and triglyceride excursions following a standardized meal in individuals with diabetes: ELSA-Brasil study

    OpenAIRE

    Riboldi, B?rbara P; Luft, Vivian C; de Castilhos, Cristina D; de Cardoso, Let?cia O; Schmidt, Maria I; Barreto, Sandhi M; de Sander, Maria F; Alvim, Sheila M; Duncan, Bruce B

    2015-01-01

    Objective: To assess glucose and triglyceride excursions 2 hours after the ingestion of a standardized meal and their associations with clinical characteristics and cardiovascular complications in individuals with diabetes. Research design and methods: Blood samples of 898 subjects with diabetes were collected at fasting and 2 hours after a meal containing 455 kcal, 14 g of saturated fat and 47 g of carbohydrates. Self-reported morbidity, socio-demographic characteristics and clinical measure...

  7. Estimation method for first excursion probability of secondary system with impact and friction using maximum response

    International Nuclear Information System (INIS)

    Shigeru Aoki

    2005-01-01

    The secondary system such as pipings, tanks and other mechanical equipment is installed in the primary system such as building. The important secondary systems should be designed to maintain their function even if they are subjected to destructive earthquake excitations. The secondary system has many nonlinear characteristics. Impact and friction characteristic, which are observed in mechanical supports and joints, are common nonlinear characteristics. As impact damper and friction damper, impact and friction characteristic are used for reduction of seismic response. In this paper, analytical methods of the first excursion probability of the secondary system with impact and friction, subjected to earthquake excitation are proposed. By using the methods, the effects of impact force, gap size and friction force on the first excursion probability are examined. When the tolerance level is normalized by the maximum response of the secondary system without impact or friction characteristics, variation of the first excursion probability is very small for various values of the natural period. In order to examine the effectiveness of the proposed method, the obtained results are compared with those obtained by the simulation method. Some estimation methods for the maximum response of the secondary system with nonlinear characteristics have been developed. (author)

  8. Comparison of dynamic balance in collegiate field hockey and football players using star excursion balance test.

    Science.gov (United States)

    Bhat, Rashi; Moiz, Jamal Ali

    2013-09-01

    The preliminary study aimed to compare dynamic balance between collegiate athletes competing or training in football and hockey using star excursion balance test. A total thirty university level players, football (n = 15) and field hockey (n = 15) were participated in the study. Dynamic balance was assessed by using star excursion balance test. The testing grid consists of 8 lines each 120 cm in length extending from a common point at 45° increments. The subjects were instructed to maintain a stable single leg stance with the test leg with shoes off and to reach for maximal distance with the other leg in each of the 8 directions. A pencil was used to point and read the distance to which each subject's foot reached. The normalized leg reach distances in each direction were summed for both limbs and the total sum of the mean of summed normalized distances of both limbs were calculated. There was no significant difference in all the directions of star excursion balance test scores in both the groups. Additionally, composite reach distances of both groups also found non-significant (P=0.5). However, the posterior (P=0.05) and lateral (P=0.03) normalized reach distances were significantly more in field hockey players. Field hockey players and football players did not differ in terms of dynamic balance.

  9. Conditional Probabilities in the Excursion Set Theory. Generic Barriers and non-Gaussian Initial Conditions

    CERN Document Server

    De Simone, Andrea; Riotto, Antonio

    2011-01-01

    The excursion set theory, where density perturbations evolve stochastically with the smoothing scale, provides a method for computing the dark matter halo mass function. The computation of the mass function is mapped into the so-called first-passage time problem in the presence of a moving barrier. The excursion set theory is also a powerful formalism to study other properties of dark matter halos such as halo bias, accretion rate, formation time, merging rate and the formation history of halos. This is achieved by computing conditional probabilities with non-trivial initial conditions, and the conditional two-barrier first-crossing rate. In this paper we use the recently-developed path integral formulation of the excursion set theory to calculate analytically these conditional probabilities in the presence of a generic moving barrier, including the one describing the ellipsoidal collapse, and for both Gaussian and non-Gaussian initial conditions. The non-Markovianity of the random walks induced by non-Gaussi...

  10. Reduced Bearing Excursion After Mobile-Bearing Unicompartmental Knee Arthroplasty is Associated With Poor Functional Outcomes.

    Science.gov (United States)

    Wahal, Naman; Gaba, Sahil; Malhotra, Rajesh; Kumar, Vijay; Pegg, Elise C; Pandit, Hemant

    2018-02-01

    A small proportion of patients with mobile unicompartmental knee arthroplasty (UKA) report poor functional outcomes in spite of optimal component alignment on postoperative radiographs. The purpose of this study is to assess whether there is a correlation between functional outcome and knee kinematics. From a cohort of consecutive cases of 150 Oxford medial UKA, patients with fair/poor functional outcome at 1-year postsurgery (Oxford Knee Score [OKS] bearing position with knee flexion angle. Mean OKS in the fair/poor group was 29.9 and the mean OKS in the good/excellent group was 41.1. The tibial slope, time taken to complete the exercises, and patellar tendon angle trend over the flexion range were similar in both the groups; however, bearing position and the extent of bearing excursion differed significantly. The total bearing excursion in the OKS bearing was positioned 1.7 mm more posterior on the tibia in the OKS bearing excursion and positioning, are associated with worse functional outcomes after mobile UKA. Copyright © 2017 Elsevier Inc. All rights reserved.

  11. Duality and noncommutative planes

    DEFF Research Database (Denmark)

    Jøndrup, Søren

    2015-01-01

    We study extensions of simple modules over an associative ring A   and we prove that for twosided ideals mm and nn with artinian factors the condition ExtA1(A/m,A/n)≠0 holds for the left A  -modules A/mA/m and A/nA/n if and only if it holds for the right modules A/nA/n and A/mA/m. The methods pro...... proving this are applied to show that noncommutative models of the plane, i.e. algebras of the form k〈x,y〉/(f)k〈x,y〉/(f), where f∈([x,y])f∈([x,y]) are noetherian only in case (f)=([x,y])...

  12. Systolic Blood Pressure Accuracy Enhancement in the Electronic Palpation Method Using Pulse Waveform

    National Research Council Canada - National Science Library

    Sorvoja, H

    2001-01-01

    .... Systolic pressure errors were defined and correlations with other specific values, like pressure rise time, pulse wave velocity, systolic pressure, augmentation, arm circumference and body mass index were calculated...

  13. Atrial Fibrillation Ablation in Systolic Dysfunction: Clinical and Echocardiographic Outcomes

    Directory of Open Access Journals (Sweden)

    Tasso Julio Lobo

    2015-01-01

    Full Text Available Background: Heart failure and atrial fibrillation (AF often coexist in a deleterious cycle. Objective: To evaluate the clinical and echocardiographic outcomes of patients with ventricular systolic dysfunction and AF treated with radiofrequency (RF ablation. Methods: Patients with ventricular systolic dysfunction [ejection fraction (EF <50%] and AF refractory to drug therapy underwent stepwise RF ablation in the same session with pulmonary vein isolation, ablation of AF nests and of residual atrial tachycardia, named "background tachycardia". Clinical (NYHA functional class and echocardiographic (EF, left atrial diameter data were compared (McNemar test and t test before and after ablation. Results: 31 patients (6 women, 25 men, aged 37 to 77 years (mean, 59.8±10.6, underwent RF ablation. The etiology was mainly idiopathic (19 p, 61%. During a mean follow-up of 20.3±17 months, 24 patients (77% were in sinus rhythm, 11 (35% being on amiodarone. Eight patients (26% underwent more than one procedure (6 underwent 2 procedures, and 2 underwent 3 procedures. Significant NYHA functional class improvement was observed (pre-ablation: 2.23±0.56; postablation: 1.13±0.35; p<0.0001. The echocardiographic outcome also showed significant ventricular function improvement (EF pre: 44.68%±6.02%, post: 59%±13.2%, p=0.0005 and a significant left atrial diameter reduction (pre: 46.61±7.3 mm; post: 43.59±6.6 mm; p=0.026. No major complications occurred. Conclusion: Our findings suggest that AF ablation in patients with ventricular systolic dysfunction is a safe and highly effective procedure. Arrhythmia control has a great impact on ventricular function recovery and functional class improvement.

  14. Iron deficiency in chronic systolic heart failure(indic study

    Directory of Open Access Journals (Sweden)

    Sunil Verma

    2016-01-01

    Full Text Available Background: Chronic systolic heart failure (HF is characterized by the left ventricular dysfunction, exercise intolerance and is associated with neurohormonal activation that affects several organs such as kidney and skeletal muscle. Anemia is common in HF and may worsen symptoms. Iron deficiency (ID is also common in HF patients with or without anemia. Iron is the key cofactor in oxidative metabolism in skeletal muscle and the Krebs cycle. There is a paucity of data regarding iron metabolism in chronic systolic HF in India. Methods: IroN Deficiency In CHF study (INDIC is an observational study that investigated forty chronic heart failure patients for the presence of ID. Serum ferritin (micrograms per liter, serum iron (micrograms per liter, total iron binding capacity (micrograms per liter, transferring (milligrams per deciliter, and transferrin saturation were measured to assess iron status. Results: There were 67.5% (27/40 patients who had ID with a mean serum ferritin level of 76.4 μg/L. Of the 27 iron deficient patients, 22 (55% had an absolute ID, and 5 had a functional ID. Eight out of 27 of the iron deficient patients were anemic (20% of the total cohort, 30% of the iron deficient patients. Anemia was seen in 6 other patients, which was possibly anemia of chronic disease. There was a trend for more advanced New York Heart Association (NYHA class (NYHA III and NYHA IV patients with ID (37.4% vs. 30.77%, P = 0.697. Conclusion: In our study, ID was very common, affecting more than half of the patients with systolic HF. Absolute ID was the most common cause of ID and patients with ID had a tendency to have advanced NYHA class. Our study also demonstrated that ID can occur in the absence of anemia (iron depletion.

  15. Semantic Versus Syntactic Cutting Planes

    OpenAIRE

    Filmus, Yuval; Hrubeš, Pavel; Lauria, Massimo

    2016-01-01

    In this paper, we compare the strength of the semantic and syntactic version of the cutting planes proof system. First, we show that the lower bound technique of Pudlák applies also to semantic cutting planes: the proof system has feasible interpolation via monotone real circuits, which gives an exponential lower bound on lengths of semantic cutting planes refutations. Second, we show that semantic refutations are stronger than syntactic ones. In particular, we give a formula for whic...

  16. Neutronics simulations on hypothetical power excursion and possible core melt scenarios in CANDU6

    International Nuclear Information System (INIS)

    Kim, Yonghee

    2015-01-01

    LOCA (Loss of coolant accident) is an outstanding safety issue in the CANDU reactor system since the coolant void reactivity is strongly positive. To deal with the LOCA, the CANDU systems are equipped with specially designed quickly-acting secondary shutdown system. Nevertheless, the so-called design-extended conditions are requested to be taken into account in the safety analysis for nuclear reactor systems after the Fukushima accident. As a DEC scenario, the worst accident situation in a CANDU reactor system is a unprotected LOCA, which is supposed to lead to a power excursion and possibly a core melt-down. In this work, the hypothetical unprotected LOCA scenario is simulated in view of the power excursion and fuel temperature changes by using a simplified point-kinetics (PK) model accounting for the fuel temperature change. In the PK model, the core reactivity is assumed to be affected by a large break LOCA and the fuel temperature is simulated to account for the Doppler effect. In addition, unlike the conventional PK simulation, we have also considered the Xe-I model to evaluate the impact of Xe during the LOCA. Also, we tried to simulate the fuel and core melt-down scenario in terms of the reactivity through a series of neutronics calculations for hypothetical core conditions. In case of a power excursion and possible fuel melt-down situation, the reactor system behavior is very uncertain. In this work, we tried to understand the impacts of fuel melt and relocation within the pressure vessel on the core reactivity and failure of pressure and calandria tubes. (author)

  17. Star Excursion Balance Test Anterior Asymmetry Is Associated With Injury Status in Division I Collegiate Athletes.

    Science.gov (United States)

    Stiffler, Mikel R; Bell, David R; Sanfilippo, Jennifer L; Hetzel, Scott J; Pickett, Kristen A; Heiderscheit, Bryan C

    2017-05-01

    Study Design Retrospective cohort. Background Star Excursion Balance Test (SEBT) performance differs by sport in healthy collegiate athletes, and lower extremity injury rates also vary by sport, sex, and athletic exposure. The relationship between SEBT performance and injury risk has not been evaluated with consideration of these additional variables, which may be necessary to fully describe the relationship between SEBT performance and injury risk. Objectives To assess the association between preseason SEBT performance and noncontact injury occurrence to the knee or ankle in Division I collegiate athletes when controlling for sport, sex, and athletic exposure. Methods Star Excursion Balance Test performance, starting status, and injury status were reviewed retrospectively in National Collegiate Athletic Association Division I collegiate athletes from a single institution. A total of 147 athletes were healthy at the time of preseason SEBT testing and either remained healthy (n = 118) or sustained a noncontact injury to the knee or ankle (n = 29) during their sport's subsequent competitive season. Side-to-side asymmetries were calculated in each direction as the absolute difference in reach distance between limbs. Star Excursion Balance Test reach distances and asymmetries were compared between groups using multivariable regression, controlling for sport, sex, and athletic exposure (starter, nonstarter). Receiver operating characteristic curves were used to determine optimal sensitivity and specificity for significant models. Results When controlling for sport, sex, and athletic exposure, SEBT side-to-side asymmetry in the anterior direction, expressed as an absolute or normalized to limb length, discriminated between injured and noninjured athletes (area under the curve greater than 0.82). Conclusion Assessing side-to-side reach asymmetry in the anterior direction of the SEBT may assist in identifying collegiate athletes who are at risk for sustaining noncontact

  18. Analyses of hypothetical nuclear criticality excursions in 10- and 20-MW freezer/sublimer vessels

    International Nuclear Information System (INIS)

    Haught, C.F.; Jordan, W.C.; Basoglu, B.; Dodds, H.L.; Wilkinson, A.D.

    1995-01-01

    A theoretical model is used to predict the consequences of a postulated hypothetical nuclear criticality excursion in a freezer/sublimer (F/S). Previous work has shown that an intrusion of water into a F/S may result in a critical configuration. A first attempt is made to model the neutronic and thermal-hydraulic phenomena occurring during a criticality excursion involving both uranium hexafluoride (UF 6 ) and uranyl fluoride (UO 2 F 2 ) solution, which is present in the F/S during upset conditions. The model employs point neutronics coupled with simple thermal hydraulics. Reactivity feedback from changes in the properties of the system are included in the model. The excursion is studied in a 10-MW F/S with an initial load of 3,500 kg of 5% weight enriched UF 6 and in a 20-MW F/S with an initial load of 6,800 kg of 2% weight enriched UF 6 . The magnitude of the fission release determined in this work is 5.93 x 10 18 fissions in the 10-MW F/S and 4.21 x 10 18 fissions in the 20-MW F/S. In order to demonstrate the reliability of the techniques used in this work, a limited validation study was conducted by comparing the fission release and peak fission rate determined by this work with experimental results for a limited number of experiments. The agreement between calculations and experiments in the validation study is considered to be satisfactory. The calculational results for the hypothetical accidents in the two F/S vessels appear reasonable

  19. Visual evidence of the Sterno-Etrussia geomagnetic excursion (~2700 BP)?

    Science.gov (United States)

    Raspopov, O. M.; Dergachev, V. A.; Goos'kova, E. G.; Morner, N.-A.

    2003-04-01

    In the Bible's Old Testament Book of Ezekiel there is a description of the Ezekiel's vision of "a great cloud with brightness round about it" to the north of the observation site. The event described in the Bible occurred in 593 BC, i.e., approximately 2600 years ago. Ezekiel was at that time approximately 100 km south of Babylon (latitude ~ 32 N, longitude ~ 45 E). Auroral specialists interpret the Ezekiel's vision as observation of coronal auroral displays at low latitudes. However, to support this hypothesis, it is necessary to understand the physical mechanism responsible for generation of these forms of auroras at low latitudes. Analysis of palaeo- and archaeomagnetic data, including our data on magnetic properties of sediments of the Barents and White Seas and the literature data, has shown that about 2700 BP, i.e., in Ezekiel's time, development of a geomagnetic "Sterno-Etrussia" excursion took place. The duration of the excursion during which the northern geomagnetic pole wandered to the Southern Hemisphere was no more than 200-300 years. Manifestations of this excursion were found in 16 regions of the Eurasian continent and adjacent seas and also in the North and South America. By plotting the path along which the northern geomagnetic pole wandered to the southern latitudes during this excursion on the basis of palaeomagnetic data, we have found that it wandered in the longitude sector plus or minus 30 degrees, and about 2700 BP the northern geomagnetic pole was at the longitude close to the Babylon longitude, where Ezekiel had his vision. Thus, at that time Babylon was at high geomagnetic latitudes where regular coronal auroral displays occur. Records of observation of the unusual brightness of the sky in the V-VI centuries BC can also be found in Greek chronicles. This indicates that the Ezekiel's vision was not the only observation of auroras at low latitudes during the period considered here. This work was supported by INTAS, Grant 97-31008 and PFBR

  20. Postmeal exercise blunts postprandial glucose excursions in people on metformin monotherapy.

    Science.gov (United States)

    Erickson, Melissa L; Little, Jonathan P; Gay, Jennifer L; McCully, Kevin K; Jenkins, Nathan T

    2017-08-01

    Metformin is used clinically to reduce fasting glucose with minimal effects on postprandial glucose. Postmeal exercise reduces postprandial glucose and may offer additional glucose-lowering benefit beyond that of metformin alone, yet controversy exists surrounding exercise and metformin interactions. It is currently unknown how postmeal exercise and metformin monotherapy in combination will affect postprandial glucose. Thus, we examined the independent and combined effects of postmeal exercise and metformin monotherapy on postprandial glucose. A randomized crossover design was used to assess the influence of postmeal exercise on postprandial glucose excursions in 10 people treated with metformin monotherapy (57 ± 10 yr, HbA 1C  = 6.3 ± 0.6%). Each participant completed the following four conditions: sedentary and postmeal exercise (5 × 10-min bouts of treadmill walking at 60% V̇o 2max ) with metformin and sedentary and postmeal exercise without metformin. Peak postprandial glucose within a 2-h time window and 2-h total area under the curve was assessed after a standardized breakfast meal, using continuous glucose monitoring. Postmeal exercise significantly blunted 2-h peak ( P = 0.001) and 2-h area under the curve ( P = 0.006), with the lowest peak postprandial glucose excursion observed with postmeal exercise and metformin combined ( P exercise: 9.7 ± 2.3, washout/sedentary: 13.3 ± 3.2, washout/exercise: 11.1 ± 3.4 mmol/l). Postmeal exercise and metformin in combination resulted in the lowest peak postprandial glucose excursion compared with either treatment modality alone. Exercise timed to the postprandial phase may be important for optimizing glucose control during metformin monotherapy. NEW & NOTEWORTHY The interactive effects of metformin and exercise on key physiological outcomes remain an area of controversy. Findings from this study show that the combination of metformin monotherapy and moderate-intensity postmeal exercise led to

  1. Temperature measurement on Zircaloy-clad fuel pins during high temperature excursions

    International Nuclear Information System (INIS)

    Meservey, R.H.

    1976-04-01

    The development of a sheathed thermocouple suitable for attachment to zircaloy-clad fuel rods and for use during high temperature (2,800 0 F) excursions under loss-of-coolant accident conditions is described. Development, fabrication, and testing of the thermocouples is covered in detail. In addition, the development of a process for laser welding the thermocouples to fuel rods is discussed. The thermocouples and attachment welds have been tested for resistance to corrosion and nuclear radiation and have been subjected to fast thermal cycle, risetime, and blowdown accident tests

  2. Left ventricular systolic and diastolic function in hyperthyroidism

    International Nuclear Information System (INIS)

    Friedman, M.J.; Okada, R.D.; Ewy, G.A.; Hellman, D.J.

    1982-01-01

    In order to assess the effect of hyperthyroidism on systolic and diastolic function of the left ventricle, M-mode echocardiograms and systolic time intervals were obtained in 13 patients while they were clinically hyperthyroid and again when they were euthyroid following radioactive iodine therapy. Echocardiographic tracings of the septum and left ventricular posterior wall were digitized and analyzed to provide the maximum velocity of shortening and maximum velocity of lengthening. These velocities were normalized for left ventricular diastolic dimension. The left ventricular minor axis fractional shortening and the normalized maximum velocity of shortening were both increased during the hyperthyroid state. The normalized maximum velocity of lengthening, a measure of diastolic left ventricular function, was also increased during the hyperthyroid state when compared to the euthyroid state. The preejection period index and the preejection period/left ventricular ejection time ratio were lower when the patients were hyperthyroid than when they were euthyroid. These data confirm the increased inotropic state and demonstrated increased diastolic relaxation velocities of the hyperthyroid left ventricle

  3. Gravitational Couplings for Gop-Planes and y-Op-Planes

    OpenAIRE

    Giraldo, Juan Fernando Ospina

    2000-01-01

    The Wess-Zumino actions for generalized orientifold planes (GOp-planes) and y-deformed orientifold planes (yOp-planes) are presented and two series power expantions are realized from whiches processes that involves GOp-planes,yOp-planes, RR-forms, gravitons and gaugeons, are obtained. Finally non-standard GOp-planes and y-Op-planes are showed.

  4. Conceptual Design of Wave Plane

    DEFF Research Database (Denmark)

    Frigaard, Peter; Trewers, Andrew; Kofoed, Jens Peter

    The Wave Plane is a patented Wave Energy device of the overtopping type, designed to capture potential as well as kinetic energy. This is as such different to other overtopping devices, who usually only focus on potential energy. If Wave Plane A/S can deliver the turbine technology to utilize both...

  5. Mary Poppins and the Soviet Pilgrimage: P.L.Travers's Moscow Excursion (1934

    Directory of Open Access Journals (Sweden)

    John McNair

    2013-02-01

    Full Text Available Like the journey it chronicles, Moscow Excursion, P.L.Travers’s account of her 1932 visit to Russia, was in part inspired by the genre it effectively parodies: the ‘Soviet pilgrimage’ ‘truth about Russia’ narrative characteristic of the Stalin decades and exemplified (in the Australian context by Katharine Susannah Prichard’s The Real Russia, also published in 1934. The paper examines the ways in which Travers’s book is written against this genre to produce an avowedly ‘un-political’ record whose narrator rejects the restrictions of organized travel, and whose idiosyncratic and critical observations on Soviet reality contrast with the admiration of her more orthodox fellow-travellers for the usual showcase institutions on the official itinerary. At the same time, it is argued that in its blend of self-deprecating irony, whimsy and disillusioned idealism Moscow Excursion suggests parallels with Travers’s personal quest for ‘the truth’ and even with Mary Poppins, published only two months later.

  6. Variations in Star Excursion Balance Test Performance Between High School and Collegiate Football Players.

    Science.gov (United States)

    McCann, Ryan S; Kosik, Kyle B; Beard, Megan Q; Terada, Masafumi; Pietrosimone, Brian G; Gribble, Phillip A

    2015-10-01

    The Star Excursion Balance Test (SEBT) is a reliable inexpensive tool used to assess dynamic postural control deficits and efficacy in the prediction of musculoskeletal injuries, but with little previous consideration for performance differences across age and skill levels. The purpose of this study was to examine differences in SEBT scores between high school and collegiate football players. Three-hundred eighteen high school football players and 180 National Collegiate Athletic Association Division I collegiate football players volunteered to participate. Star Excursion Balance Test scores were obtained bilaterally for anterior (ANT), posterolateral (PL), and posteromedial (PM) directions, and for an overall composite (COMP) score. The mean of 3 trials from each leg was normalized to stance leg length and presented as a percentage score. Bilaterally averaged scores were compared between high school and collegiate football players using separate independent t-tests. A multiple linear backward regression determined the amount of variance in SEBT scores explained by age, mass, and height. Compared with collegiate athletes, high school athletes had lower PL (72.8 ± 11.4% vs. 77.1 ± 10.2%; p football players.

  7. [Clinical characteristics and medium-term prognosis of patients with heart failure and preserved systolic function. Do they differ in systolic dysfunction?].

    Science.gov (United States)

    Ojeda, Soledad; Anguita, Manuel; Muñoz, Juan F; Rodríguez, Marcos T; Mesa, Dolores; Franco, Manuel; Ureña, Isabel; Vallés, Federico

    2003-11-01

    To assess the prevalence, clinical profile and medium-term prognosis in patients with heart failure and preserved systolic ventricular function compared to those with systolic dysfunction. 153 patients were included, 62 with preserved systolic ventricular function (left ventricular ejection fraction > or = 45%) and 91 with impaired systolic ventricular function (left ventricular ejection fraction < 45%). The mean follow-up period was 25 10 months. Mean age was similar (66 10 vs. 65 10; p = 0.54). There was a higher proportion of women among patients with preserved systolic function (53% vs. 28%; p < 0.01). Ischemic and idiopathic cardiomyopathy were the most common causes of heart failure in patients with systolic dysfunction, whereas valvular disease and hypertensive cardiopathy were the most common in patients with preserved systolic function. Angiotensin-converting enzyme inhibitors and beta-blockers were more often prescribed in patients with impaired systolic ventricular function (86% vs. 52%; p < 0.01 and 33% vs. 11%; p < 0.01, respectively). There were no differences between the groups in terms of mortality rate (37% vs. 29%), readmission rate for other causes (29% vs. 23%), readmission rate for heart failure (45% vs. 45%), cumulative survival (51% vs. 62%) and the likelihood of not being readmitted for heart failure (50% vs. 52%). In the multivariate analysis, left ventricular ejection fraction was not a predictor of death or readmission because of heart failure. In a large proportion of patients with heart failure, systolic ventricular function is preserved. Despite the clinical differences between patients with preserved and impaired systolic ventricular function, the medium-term prognosis was similar in both groups.

  8. High Performance Systolic Array Core Architecture Design for DNA Sequencer

    Directory of Open Access Journals (Sweden)

    Saiful Nurdin Dayana

    2018-01-01

    Full Text Available This paper presents a high performance systolic array (SA core architecture design for Deoxyribonucleic Acid (DNA sequencer. The core implements the affine gap penalty score Smith-Waterman (SW algorithm. This time-consuming local alignment algorithm guarantees optimal alignment between DNA sequences, but it requires quadratic computation time when performed on standard desktop computers. The use of linear SA decreases the time complexity from quadratic to linear. In addition, with the exponential growth of DNA databases, the SA architecture is used to overcome the timing issue. In this work, the SW algorithm has been captured using Verilog Hardware Description Language (HDL and simulated using Xilinx ISIM simulator. The proposed design has been implemented in Xilinx Virtex -6 Field Programmable Gate Array (FPGA and improved in the core area by 90% reduction.

  9. Modelling the heart with the atrioventricular plane as a piston unit.

    Science.gov (United States)

    Maksuti, Elira; Bjällmark, Anna; Broomé, Michael

    2015-01-01

    Medical imaging and clinical studies have proven that the heart pumps by means of minor outer volume changes and back-and-forth longitudinal movements in the atrioventricular (AV) region. The magnitude of AV-plane displacement has also shown to be a reliable index for diagnosis of heart failure. Despite this, AV-plane displacement is usually omitted from cardiovascular modelling. We present a lumped-parameter cardiac model in which the heart is described as a displacement pump with the AV plane functioning as a piston unit (AV piston). This unit is constructed of different upper and lower areas analogous with the difference in the atrial and ventricular cross-sections. The model output reproduces normal physiology, with a left ventricular pressure in the range of 8-130 mmHg, an atrial pressure of approximatly 9 mmHg, and an arterial pressure change between 75 mmHg and 130 mmHg. In addition, the model reproduces the direction of the main systolic and diastolic movements of the AV piston with realistic velocity magnitude (∼10 cm/s). Moreover, changes in the simulated systolic ventricular-contraction force influence diastolic filling, emphasizing the coupling between cardiac systolic and diastolic functions. The agreement between the simulation and normal physiology highlights the importance of myocardial longitudinal movements and of atrioventricular interactions in cardiac pumping. Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

  10. Systolic Compression of Epicardial Coronary and Intramural Arteries

    Science.gov (United States)

    Mohiddin, Saidi A.; Fananapazir, Lameh

    2002-01-01

    It has been suggested that systolic compression of epicardial coronary arteries is an important cause of myocardial ischemia and sudden death in children with hypertrophic cardiomyopathy. We examined the associations between sudden death, systolic coronary compression of intra- and epicardial arteries, myocardial perfusion abnormalities, and severity of hypertrophy in children with hypertrophic cardiomyopathy. We reviewed the angiograms from 57 children with hypertrophic cardiomyopathy for the presence of coronary and septal artery compression; coronary compression was present in 23 (40%). The left anterior descending artery was most often affected, and multiple sites were found in 4 children. Myocardial perfusion abnormalities were more frequently present in children with coronary compression than in those without (94% vs 47%, P = 0.002). Coronary compression was also associated with more severe septal hypertrophy and greater left ventricular outflow gradient. Septal branch compression was present in 65% of the children and was significantly associated with coronary compression, severity of septal hypertrophy, and outflow obstruction. Multivariate analysis showed that septal thickness and septal branch compression, but not coronary compression, were independent predictors of perfusion abnormalities. Coronary compression was not associated with symptom severity, ventricular tachycardia, or a worse prognosis. We conclude that compression of coronary arteries and their septal branches is common in children with hypertrophic cardiomyopathy and is related to the magnitude of left ventricular hypertrophy. Our findings suggest that coronary compression does not make an important contribution to myocardial ischemia in hypertrophic cardiomyopathy; however, left ventricular hypertrophy and compression of intramural arteries may contribute significantly. (Tex Heart Inst J 2002;29:290–8) PMID:12484613

  11. A comparison between brachial and echocardiographic systolic time intervals.

    Directory of Open Access Journals (Sweden)

    Ho-Ming Su

    Full Text Available Systolic time interval (STI is an established noninvasive technique for the assessment of cardiac function. Brachial STIs can be automatically determined by an ankle-brachial index (ABI-form device. The aims of this study are to evaluate whether the STIs measured from ABI-form device can represent those measured from echocardiography and to compare the diagnostic values of brachial and echocardiographic STIs in the prediction of left ventricular ejection fraction (LVEF <50%. A total of 849 patients were included in the study. Brachial pre-ejection period (bPEP and brachial ejection time (bET were measured using an ABI-form device and pre-ejection period (PEP and ejection time (ET were measured from echocardiography. Agreement was assessed by correlation coefficient and Bland-Altman plot. Brachial STIs had a significant correlation with echocardiographic STIs (r = 0.644, P<0.001 for bPEP and PEP; r  = 0.850, P<0.001 for bET and ET; r = 0.708, P<0.001 for bPEP/bET and PEP/ET. The disagreement between brachial and echocardiographic STIs (brachial STIs minus echocardiographic STIs was 28.55 ms for bPEP and PEP, -4.15 ms for bET and ET and -0.11 for bPEP/bET and PEP/ET. The areas under the curve for bPEP/bET and PEP/ET in the prediction of LVEF <50% were 0.771 and 0.765, respectively. Brachial STIs were good alternatives to STIs obtained from echocardiography and also helpful in prediction of LVEF <50%. Brachial STIs automatically obtained from an ABI-form device may be helpful for evaluation of left ventricular systolic dysfunction.

  12. A school excursion to a museum can promote physical activity in children by integrating movement into curricular activities

    DEFF Research Database (Denmark)

    Mygind, Lærke; Kryger, Tine; Sidenius, Gry

    2017-01-01

    Since children spend a large proportion of their time in institutional settings such as schools, health promotion researchers have identified this as an important setting to promote physical activity (PA). Apart from physical education, PA could be integrated into the school curriculum in other...... consisted of an excursion day to a museum. While an increase in light physical activity and reduction in the amount of sedentary time was observed, students did not spend more time in moderate to vigorous PA (MVPA) during the visit to the museum than on a regular school day. However, over the full excursion...... day, the students accumulated more MVPA. One school used active transportation to and from the museum, which contributed to significantly more MVPA compared to the other schools. An excursion to a museum significantly reduced sedentary time, but was in itself not sufficient to increase MVPA....

  13. Analysis of LOF/TOP excursions in the SNR-300 Zielkern core with a stress controlled rip extension after failure

    International Nuclear Information System (INIS)

    Royl, P.

    1987-07-01

    An unprotected loss of flow (ULOF) accident can result in energetic power excursions due to reactivity effects from in-pile fuel motion and compaction after a near midplane failure of fuel pins in unvoided regions of the core (loss of flow driven transient overpower or LOF/TOP excursions). These excursions are strongly mitigated by a propagation of the failure rip, which reduces the fuel compaction and enhances fuel sweep-out. A simple model has been introduced into the SAS3D code in which this propagation is restricted to the expansion of the void zone that is firmed in the coolant channel due to thermal interactions of fuel and sodium (FCI) after failure. The rip propagation is demonstrated in this report in all investigated cases to be a strong mitigator that will limit the fuel compaction effects in the region where they originate

  14. A school excursion to a museum can promote physical activity in children by integrating movement into curricular activities

    DEFF Research Database (Denmark)

    Mygind, Lærke; Kryger, Tine B; Sidenius, Gry

    2018-01-01

    day, the students accumulated more MVPA. One school used active transportation to and from the museum, which contributed to significantly more MVPA compared to the other schools. An excursion to a museum significantly reduced sedentary time, but was in itself not sufficient to increase MVPA.......Since children spend a large proportion of their time in institutional settings such as schools, health promotion researchers have identified this as an important setting to promote physical activity (PA). Apart from physical education, PA could be integrated into the school curriculum in other...... consisted of an excursion day to a museum. While an increase in light physical activity and reduction in the amount of sedentary time was observed, students did not spend more time in moderate to vigorous PA (MVPA) during the visit to the museum than on a regular school day. However, over the full excursion...

  15. Generating asymptotically plane wave spacetimes

    International Nuclear Information System (INIS)

    Hubeny, Veronika E.; Rangamani, Mukund

    2003-01-01

    In an attempt to study asymptotically plane wave spacetimes which admit an event horizon, we find solutions to vacuum Einstein's equations in arbitrary dimension which have a globally null Killing field and rotational symmetry. We show that while such solutions can be deformed to include ones which are asymptotically plane wave, they do not posses a regular event horizon. If we allow for additional matter, such as in supergravity theories, we show that it is possible to have extremal solutions with globally null Killing field, a regular horizon, and which, in addition, are asymptotically plane wave. In particular, we deform the extremal M2-brane solution in 11-dimensional supergravity so that it behaves asymptotically as a 10-dimensional vacuum plane wave times a real line. (author)

  16. Two-transitive MInkowski planes

    NARCIS (Netherlands)

    Wilbrink, H.A.

    1982-01-01

    In this paper we determine all finite Minkowski planes with an automorphism group which satisfies the following transitivity property: any ordered pair of nonparallel points can be mapped onto any other ordered pair of nonparallel points.

  17. The use of genetic programming to develop a predictor of swash excursion on sandy beaches

    Directory of Open Access Journals (Sweden)

    M. Passarella

    2018-02-01

    Full Text Available We use genetic programming (GP, a type of machine learning (ML approach, to predict the total and infragravity swash excursion using previously published data sets that have been used extensively in swash prediction studies. Three previously published works with a range of new conditions are added to this data set to extend the range of measured swash conditions. Using this newly compiled data set we demonstrate that a ML approach can reduce the prediction errors compared to well-established parameterizations and therefore it may improve coastal hazards assessment (e.g. coastal inundation. Predictors obtained using GP can also be physically sound and replicate the functionality and dependencies of previous published formulas. Overall, we show that ML techniques are capable of both improving predictability (compared to classical regression approaches and providing physical insight into coastal processes.

  18. The use of genetic programming to develop a predictor of swash excursion on sandy beaches

    Science.gov (United States)

    Passarella, Marinella; Goldstein, Evan B.; De Muro, Sandro; Coco, Giovanni

    2018-02-01

    We use genetic programming (GP), a type of machine learning (ML) approach, to predict the total and infragravity swash excursion using previously published data sets that have been used extensively in swash prediction studies. Three previously published works with a range of new conditions are added to this data set to extend the range of measured swash conditions. Using this newly compiled data set we demonstrate that a ML approach can reduce the prediction errors compared to well-established parameterizations and therefore it may improve coastal hazards assessment (e.g. coastal inundation). Predictors obtained using GP can also be physically sound and replicate the functionality and dependencies of previous published formulas. Overall, we show that ML techniques are capable of both improving predictability (compared to classical regression approaches) and providing physical insight into coastal processes.

  19. Excursions in classical analysis pathways to advanced problem solving and undergraduate research

    CERN Document Server

    Chen, Hongwei

    2010-01-01

    Excursions in Classical Analysis introduces undergraduate students to advanced problem solving and undergraduate research in two ways. Firstly, it provides a colourful tour of classical analysis which places a wide variety of problems in their historical context. Secondly, it helps students gain an understanding of mathematical discovery and proof. In demonstrating a variety of possible solutions to the same sample exercise, the reader will come to see how the connections between apparently inapplicable areas of mathematics can be exploited in problem-solving. This book will serve as excellent preparation for participation in mathematics competitions, as a valuable resource for undergraduate mathematics reading courses and seminars and as a supplement text in a course on analysis. It can also be used in independent study, since the chapters are free-standing.

  20. Paleointensities of the Auckland Excursion from Volcanic Rocks in New Zealand

    Science.gov (United States)

    Mochizuki, N.; Tsunakawa, H.; Shibuya, H.; Cassidy, J.; Smith, I. E.

    2001-12-01

    Shibuya et al. (1992) reported the Auckland excursion from several basaltic lava flows of monogenetic volcanic centers (Auckland Volcanic Field, New Zealand. The Auckland excursion was recorded in five centers in three intermediate direction groups of north-down, west and south. We carried out paleointensity and rock-magnetic studies in order to obtain the absolute paleointensities associated with three intermediate geomagnetic fields. Thermomagnetic analyses indicated typical Curie temperatures of 150-200, 450-500 and/or 550-580 oC. The Day plot (Day et al., 1977) showed a linear trend in the pseudo-single-domain range of magnetic carriers. Those results, combined with the reflection microscope observations, identified the magnetic carriers as titanomagnetites with wide variation in titanium content and grain size. First, the Coe's version of the Thellier method (Coe, 1967) was applied to the samples. Several samples seemed to give paleointensities ranging from 3.2 to 6.4 μ T (Shibuya and Cassidy, 1995 AGU fall meeting), but they were often affected by thermal alteration in the furnace even from fairly low temperature steps like 200oC. We were forced to introduce correction for thermal alterations in laboratory heating, using low temperature part of the Arai plot. We, therefore, applied the double heating technique (DHT) of Shaw method (Tsunakawa and Shaw, 1994), which was capable of detecting inappropriate results by the ARM correction, to the samples. The low temperature demagnetization (LTD) was combined with DHT (Yamamoto et al., submitted) before AF demagnetization and samples were heated in a vacuum of 10-100 Pa. Sixty-one samples from the five lava flows were subjected to the LTD-DHT Shaw method. Twenty-three of these samples yielded successful results passing the selection criteria. Five out of six paleointensities from the Crater Hill lava were consistent with each other. A mean paleointensity was given to be 10.9+/- 1.9 μ T (N=5) for the Crater Hill

  1. Limnologic-geologic excursion in the territory of the lower Erft River

    Energy Technology Data Exchange (ETDEWEB)

    Friedrich, G.; Thome, K.N.

    1976-01-01

    The geography and hydrology of the area of the excursion are described. There is much damage due to brown coal strip mining operations. Ground water was drained through a canal leading to the Erft River. The water in nearby springs is rich in Fe which repels plant life. The canal contains only a few blue algae (Oscillatoria splendida) and filamentous green algae (Ulothrix tenerrima) which tolerate high Fe concentrations. The Erft shore plant population includes Sparganium erectum, Potamogeton natans, P. pectinatus and Ranunculus fluitans. On flowering plants and stones, diatoms, various green algae (Cladophora glomerata, Stigeoclonium tenue, Oedogonium capillare) and the tropical red alga Compsopogon hookeri were found. The macrozoobenthos is composed mainly of snails (Bithynia tenaculata, Lumnaea ovata, Physa fontinalis, P. acuta and worms of North American origin (Dugesia tifrina, Dendrocoelum lacteum and Planaria lugubris). The Isopoda included Asellus coxalis and A. aquaticus. Leeches (Herpobdella octoculata) and insect larvae (Chironomids, Limnephilids) were also found.

  2. Analysis of the progression of systolic blood pressure using imputation of missing phenotype values

    OpenAIRE

    Vaitsiakhovich, Tatsiana; Drichel, Dmitriy; Angisch, Marina; Becker, Tim; Herold, Christine; Lacour, André

    2014-01-01

    We present a genome-wide association study of a quantitative trait, "progression of systolic blood pressure in time," in which 142 unrelated individuals of the Genetic Analysis Workshop 18 real genotype data were analyzed. Information on systolic blood pressure and other phenotypic covariates was missing at certain time points for a considerable part of the sample. We observed that the dropout process causing missingness is not independent of the initial systolic blood pressure; that is, the ...

  3. Diastolic effects of chronic digitalization in systolic heart failure.

    Science.gov (United States)

    Hassapoyannes, C A; Bergh, M E; Movahed, M R; Easterling, B M; Omoigui, N A

    1998-10-01

    The efficacy of short-term digitalization on exercise tolerance may, in part, reflect enhanced diastolic performance. However, cardiac glycosides can impair ventricular relaxation from cytosolic Ca++ overload. To detect any time-dependent adverse effect, we assessed the diastolic function after long-term use of digitalis in patients with mild to moderate systolic left ventricular failure. From a cohort of 80 patients who received long-term, randomized, double-blind treatment with digitalis versus placebo at the WJB Dorn Veterans Affairs Medical Center, 38 survivors were evaluated at the end of follow-up (mean 48.4 months) with evaluators blinded to treatment used. Each survivor underwent equilibrium scintigraphic and echocardiographic assessment of diastolic function. Peak and mean filling rates normalized with filling volume (FV), diastolic phase durations normalized with duration of diastole, and filling fractions were measured from the time-activity curve. The isovolumic relaxation period and ventricular dimensions were computed echocardiographically. By actual-treatment-received analysis, treated versus untreated patients manifested a trend toward longer isovolumic relaxation (80.76 ms vs 61.54 ms, P = .06) but a markedly lower peak rapid filling rate (6.39 FV/sec vs 10.56 FV/sec, P = .02) despite comparable loading conditions. In addition, treated patients exhibited a lower mean rate of rapid filling (2.75 FV/sec vs 3.78 FV/sec, P = .05) in the absence of a longer rapid filling duration. However, the end-diastolic ventricular dimension did not differ between the 2 groups. Similar results were obtained by intention-to-treat analysis. Importantly, the mortality rate from worsening heart failure in the inception cohort was lower in the digitalis group versus the placebo group (P = .05) with no difference in total cardiac or all-cause mortality. After long-term digitalization for systolic left ventricular failure, cross-sectional comparison with a control group

  4. A comparison of economy and sagittal plane trunk movements among back-, back/front- and head-loading.

    Science.gov (United States)

    Hudson, Sean; Cooke, Carlton; Davies, Simeon; West, Sacha; Gamieldien, Raeeq; Low, Chris; Lloyd, Ray

    2018-05-14

    It has been suggested that freedom of movement in the trunk could influence load carriage economy. This study aimed to compare the economy and sagittal plane trunk movements associated with three load carriage methods that constrain posture differently. Eighteen females walked at 3 km.h -1 with loads of 0, 3, 6, 9, 12, 15 and 20 kg carried on the back, back/front and head. Load carriage economy was assessed using the Extra Load Index (ELI). Change in sagittal plane trunk forward lean and trunk angle excursion from unloaded to loaded walking were assessed. Results show no difference in economy between methods (p = 0.483), despite differences in the change in trunk forward lean (p = 0.001) and trunk angle excursion (p = 0.021) from unloaded to loaded walking. We conclude that economy is not different among the three methods of load carriage, despite significant differences in sagittal plane trunk movements.

  5. Eyelid reanimation with gold weight implant and tendon sling suspension: evaluation of excursion and velocity using the FACIAL CLIMA system.

    Science.gov (United States)

    Hontanilla, Bernardo; Marre, Diego

    2013-04-01

    This study aims to analyse the efficacy of static techniques, namely gold weight implant and tendon sling, in the reanimation of the paralytic eyelid. Upper eyelid rehabilitation in terms of excursion and blinking velocity is performed using the automatic motion capture system, FACIAL CLIMA. Seventy-four patients underwent a total of 101 procedures including 58 upper eyelid gold weight implants and 43 lower eyelid tendon suspension with 27 patients undergoing both procedures. The presence of lagophtalmos, eye dryness, corneal ulcer, epiphora and lower lid ptosis/ectropion was assessed preoperatively. The Wilcoxon signed-rank test was used to compare preoperative versus postoperative measurements of upper eyelid excursion and blinking velocity determined with FACIAL CLIMA. Significance was set at p CLIMA revealed significant improvement of eyelid excursion and velocity of blinking (p CLIMA system is a reliable method to quantify upper eyelid excursion and blinking velocity and to detect the exact position of the lower eyelid. Copyright © 2012 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.

  6. Rapid directional changes associated with a 6.5 kyr-long Blake geomagnetic excursion at the Blake-Bahama Outer Ridge

    DEFF Research Database (Denmark)

    Bourne, Mark; McNiocaill, Conall; Thomas, Alexander

    2012-01-01

    Geomagnetic excursions are recognized as intrinsic features of the Earth's magnetic field. High-resolution records of field behaviour, captured in marine sedimentary cores, present an opportunity to determine the temporal and geometric character of the field during geomagnetic excursions...... and provide constraints on the mechanisms producing field variability. We present here the highest resolution record yet published of the Blake geomagnetic excursion (similar to 125 ka) measured in three cores from Ocean Drilling Program (ODP) Site 1062 on the Blake-Bahama Outer Ridge. The Blake excursion has...... a controversial structure and timing but these cores have a sufficiently high sedimentation rate (similar to 10 cm ka(-1)) to allow detailed reconstruction of the field behaviour at this site during the excursion. Palaeomagnetic measurements of the cores reveal rapid transitions (

  7. Error Analysis on Plane-to-Plane Linear Approximate Coordinate ...

    Indian Academy of Sciences (India)

    Abstract. In this paper, the error analysis has been done for the linear approximate transformation between two tangent planes in celestial sphere in a simple case. The results demonstrate that the error from the linear transformation does not meet the requirement of high-precision astrometry under some conditions, so the ...

  8. Target blood pressure for treatment of isolated systolic hypertension in the elderly: valsartan in elderly isolated systolic hypertension study.

    Science.gov (United States)

    Ogihara, Toshio; Saruta, Takao; Rakugi, Hiromi; Matsuoka, Hiroaki; Shimamoto, Kazuaki; Shimada, Kazuyuki; Imai, Yutaka; Kikuchi, Kenjiro; Ito, Sadayoshi; Eto, Tanenao; Kimura, Genjiro; Imaizumi, Tsutomu; Takishita, Shuichi; Ueshima, Hirotsugu

    2010-08-01

    In this prospective, randomized, open-label, blinded end point study, we aimed to establish whether strict blood pressure control ( or =140 mm Hg to or =2 years. The strict control (1545 patients) and moderate control (1534 patients) groups were well matched (mean age: 76.1 years; mean blood pressure: 169.5/81.5 mm Hg). Median follow-up was 3.07 years. At 3 years, blood pressure reached 136.6/74.8 mm Hg and 142.0/76.5 mm Hg, respectively. The blood pressure difference between the 2 groups was 5.4/1.7 mm Hg. The overall rate of the primary composite end point was 10.6 per 1000 patient-years in the strict control group and 12.0 per 1000 patient-years in the moderate control group (hazard ratio: 0.89; [95% CI: 0.60 to 1.34]; P=0.38). In summary, blood pressure targets of or = 70 years of age with isolated systolic hypertension, although our trial was underpowered to definitively determine whether strict control was superior to less stringent blood pressure targets.

  9. Testing of focal plane arrays

    International Nuclear Information System (INIS)

    Merriam, J.D.

    1988-01-01

    Problems associated with the testing of focal plane arrays are briefly examined with reference to the instrumentation and measurement procedures. In particular, the approach and instrumentation used as the Naval Ocean Systems Center is presented. Most of the measurements are made with flooded illumination on the focal plane array. The array is treated as an ensemble of individual pixels, data being taken on each pixel and array averages and standard deviations computed for the entire array. Data maps are generated, showing the pixel data in the proper spatial position on the array and the array statistics

  10. Use of Inotropic Agents in Treatment of Systolic Heart Failure

    Directory of Open Access Journals (Sweden)

    Sohaib Tariq

    2015-12-01

    Full Text Available The most common use of inotropes is among hospitalized patients with acute decompensated heart failure, with reduced left ventricular ejection fraction and with signs of end-organ dysfunction in the setting of a low cardiac output. Inotropes can be used in patients with severe systolic heart failure awaiting heart transplant to maintain hemodynamic stability or as a bridge to decision. In cases where patients are unable to be weaned off inotropes, these agents can be used until a definite or escalated supportive therapy is planned, which can include coronary revascularization or mechanical circulatory support (intra-aortic balloon pump, extracorporeal membrane oxygenation, impella, left ventricular assist device, etc.. Use of inotropic drugs is associated with risks and adverse events. This review will discuss the use of the inotropes digoxin, dopamine, dobutamine, norepinephrine, milrinone, levosimendan, and omecamtiv mecarbil. Long-term inotropic therapy should be offered in selected patients. A detailed conversation with the patient and family shall be held, including a discussion on the risks and benefits of use of inotropes. Chronic heart failure patients awaiting heart transplants are candidates for intravenous inotropic support until the donor heart becomes available. This helps to maintain hemodynamic stability and keep the fluid status and pulmonary pressures optimized prior to the surgery. On the other hand, in patients with severe heart failure who are not candidates for advanced heart failure therapies, such as transplant and mechanical circulatory support, inotropic agents can be used for palliative therapy. Inotropes can help reduce frequency of hospitalizations and improve symptoms in these patients.

  11. Endothelial function in postmenopausal women with nighttime systolic hypertension.

    Science.gov (United States)

    Routledge, Faye S; Hinderliter, Alan L; McFetridge-Durdle, Judith; Blumenthal, James A; Paine, Nicola J; Sherwood, Andrew

    2015-08-01

    Hypertension becomes more prevalent in women during their postmenopausal years. Nighttime systolic blood pressure (SBP) is especially predictive of adverse cardiac events, and the relationship between rising nighttime SBP and cardiovascular risk increases more rapidly in women compared with men. The reasons for the prognostic significance of nighttime SBP are not completely known but may involve vascular endothelial dysfunction. The purposes of this study were to examine the relationship between nighttime SBP and endothelial function, as assessed by brachial artery flow-mediated dilation (FMD), and to determine whether postmenopausal women with nighttime hypertension (SBP ≥120 mm Hg) evidenced greater endothelial dysfunction compared with women with normal nighttime SBP. One hundred postmenopausal women (mean [SD] age, 65.8 [7.5] y; mean [SD] body mass index, 28.3 [4.7] kg/m; hypertension, 47%; coronary artery disease, 51%; mean [SD] clinic SBP, 137 [17] mm Hg; mean [SD] clinic diastolic blood pressure, 67 [11] mm Hg; nighttime hypertension, 34 women) underwent 24-hour ambulatory blood pressure monitoring, actigraphy, and brachial artery FMD assessment. Multivariate regression models showed that higher nighttime SBP and larger baseline artery diameter were inversely related to FMD. Nighttime SBP and baseline artery diameter accounted for 23% of the variance in FMD. After adjustment for baseline artery diameter, women with nighttime hypertension had lower mean (SD) FMD than women with normal nighttime SBP (2.95% [0.65%] vs 5.52% [0.46%], P = 0.002). Nighttime hypertension is associated with reduced endothelial function in postmenopausal women. Research examining the therapeutic benefits of nighttime hypertension treatment on endothelial function and future cardiovascular risk in postmenopausal women is warranted.

  12. Use of Inotropic Agents in Treatment of Systolic Heart Failure.

    Science.gov (United States)

    Tariq, Sohaib; Aronow, Wilbert S

    2015-12-04

    The most common use of inotropes is among hospitalized patients with acute decompensated heart failure, with reduced left ventricular ejection fraction and with signs of end-organ dysfunction in the setting of a low cardiac output. Inotropes can be used in patients with severe systolic heart failure awaiting heart transplant to maintain hemodynamic stability or as a bridge to decision. In cases where patients are unable to be weaned off inotropes, these agents can be used until a definite or escalated supportive therapy is planned, which can include coronary revascularization or mechanical circulatory support (intra-aortic balloon pump, extracorporeal membrane oxygenation, impella, left ventricular assist device, etc.). Use of inotropic drugs is associated with risks and adverse events. This review will discuss the use of the inotropes digoxin, dopamine, dobutamine, norepinephrine, milrinone, levosimendan, and omecamtiv mecarbil. Long-term inotropic therapy should be offered in selected patients. A detailed conversation with the patient and family shall be held, including a discussion on the risks and benefits of use of inotropes. Chronic heart failure patients awaiting heart transplants are candidates for intravenous inotropic support until the donor heart becomes available. This helps to maintain hemodynamic stability and keep the fluid status and pulmonary pressures optimized prior to the surgery. On the other hand, in patients with severe heart failure who are not candidates for advanced heart failure therapies, such as transplant and mechanical circulatory support, inotropic agents can be used for palliative therapy. Inotropes can help reduce frequency of hospitalizations and improve symptoms in these patients.

  13. Reference values of fetal peak systolic blood flow Velocity in the ...

    African Journals Online (AJOL)

    Objectives: The objectives of this prospective cross sectional study are (i) to establish new reference values of peak systolic blood flow velocity measurement in the fetal middle cerebral artery (MCA-PSV) following validated methodological guidelines (ii) to correlate peak systolic velocity with gestational age and (iii) to ...

  14. Left atrial systolic force in hypertensive patients with left ventricular hypertrophy: the LIFE study

    DEFF Research Database (Denmark)

    Chinali, M.; Simone, G. de; Wachtell, K.

    2008-01-01

    In hypertensive patients without prevalent cardiovascular disease, enhanced left atrial systolic force is associated with left ventricular hypertrophy and increased preload. It also predicts cardiovascular events in a population with high prevalence of obesity. Relations between left atrial...... systolic force and left ventricular geometry and function have not been investigated in high-risk hypertrophic hypertensive patients. Participants in the Losartan Intervention For Endpoint reduction in hypertension echocardiography substudy without prevalent cardiovascular disease or atrial fibrillation (n...... = 567) underwent standard Doppler echocardiography. Left atrial systolic force was obtained from the mitral orifice area and Doppler mitral peak A velocity. Patients were divided into groups with normal or increased left atrial systolic force (>14.33 kdyn). Left atrial systolic force was high in 297...

  15. Physiological Responses Associated with Nordic-Walking Training in Systolic Hypertensive Postmenopausal Women

    Directory of Open Access Journals (Sweden)

    Latosik Ewelina

    2014-12-01

    Full Text Available Loss of physical strength and hypertension are among the most pronounced detrimental factors accompanying aging. The aim of this study was to evaluate the influence of a supervised 8-week Nordic-walking training program on systolic blood pressure in systolic-hypertensive postmenopausal women. This study was a randomized control trial on a sample of 24 subjects who did not take any hypertension medications. There was a statistically significant decrease in systolic blood pressure and an increase in lower and upper-body strength in the group following Nordic-walking training. There was a decrease in serum levels of total cholesterol, triglycerides, and low-density cholesterol. The obtained results indicate that an 8-week Nordic-walking program may be efficiently employed for counteracting systolic hypertension through a direct abatement of systolic blood pressure and an increase of maximal aerobic capacity.

  16. Geological setting of the Olkiluoto investigation site, Eurajoki, SW Finland. Excursion guidebook

    International Nuclear Information System (INIS)

    Paulamaeki, S.

    2009-08-01

    -1250 million years in age. Their geochemical features suggest that they are feeder channels to continental flood basalts, which have not, however, been preserved in the Satakunta area. Lake Saeaeksjaervi, northeast of the Satakunta sandstone, hosts approximately 4.5 km wide impact structure of early Cambrian age (ca. 560 Ma). Below water level it contains unexposed suevite breccia and impact melt breccia. Day 1 of the field excursion introduces the Palaeoproterozoic geology of the Olkiluoto site, with special emphasis to the structural geology. Day 2 presents the Mesoproterozoic history of southern Satakunta area, including the Laitila and Eurajoki rapakivi granites, the Satakunta sandstone and the olivine diabases. The excursion ends to the Lake Saeaeksjaervi, where boulders of impact rocks can be found on the northern shore of the lake. (orig.)

  17. Interaction of gravitational plane waves

    International Nuclear Information System (INIS)

    Ferrari, V.

    1988-01-01

    The mathematical theory of colliding, infinite-fronted, plane gravitational waves is presented. The process of focusing, the creation of singularities and horizons, due to the interaction, and the lens effect due to a beam-like gravitational wave are discussed

  18. Force Lines in Plane Stress

    DEFF Research Database (Denmark)

    Rathkjen, Arne

    A state of plane stress is illustrated by means of two families of curves, each family representing constant values of a derivative of Airy's stress function. The two families of curves form a map giving in the first place an overall picture of regions of high and low stress, and in the second...

  19. Blocking sets in Desarguesian planes

    NARCIS (Netherlands)

    Blokhuis, A.; Miklós, D.; Sós, V.T.; Szönyi, T.

    1996-01-01

    We survey recent results concerning the size of blocking sets in desarguesian projective and affine planes, and implications of these results and the technique to prove them, to related problemis, such as the size of maximal partial spreads, small complete arcs, small strong representative systems

  20. Gravitational Couplings for y-Gop-Planes

    OpenAIRE

    Giraldo, Juan Fernando Ospina

    2000-01-01

    The Wess-Zumino action for y deformed and generalized orientifold planes (yGOp-planes) is presented and one power expantion is realized from which processes that involves yGOp-planes, RR-forms, gravitons and gaugeons, are obtained. Finally non-standard yGOp-planes are showed.

  1. Gravitational Couplings for Generalized Orientifold Planes

    OpenAIRE

    Giraldo, Juan Fernando Ospina

    2000-01-01

    The Wess-Zumino action for generalized orientifold planes (GOp-planes) is presented and a series power expantion is realized from which processes that involves GOp-planes, RR-forms, gravitons and gaugeons, are obtained. Finally non-standard GOp-planes are showed.

  2. Valuation of Normal Range of Ankle Systolic Blood Pressure in Subjects with Normal Arm Systolic Blood Pressure.

    Science.gov (United States)

    Gong, Yi; Cao, Kai-wu; Xu, Jin-song; Li, Ju-xiang; Hong, Kui; Cheng, Xiao-shu; Su, Hai

    2015-01-01

    This study aimed to establish a normal range for ankle systolic blood pressure (SBP). A total of 948 subjects who had normal brachial SBP (90-139 mmHg) at investigation were enrolled. Supine BP of four limbs was simultaneously measured using four automatic BP measurement devices. The ankle-arm difference (An-a) on SBP of both sides was calculated. Two methods were used for establishing normal range of ankle SBP: the 99% method was decided on the 99% reference range of actual ankle BP, and the An-a method was the sum of An-a and the low or up limits of normal arm SBP (90-139 mmHg). Whether in the right or left side, the ankle SBP was significantly higher than the arm SBP (right: 137.1 ± 16.9 vs 119.7 ± 11.4 mmHg, P<0.05). Based on the 99% method, the normal range of ankle SBP was 94~181 mmHg for the total population, 84~166 mmHg for the young (18-44 y), 107~176 mmHg for the middle-aged(45-59 y) and 113~179 mmHg for the elderly (≥ 60 y) group. As the An-a on SBP was 13 mmHg in the young group and 20 mmHg in both middle-aged and elderly groups, the normal range of ankle SBP on the An-a method was 103-153 mmHg for young and 110-160 mmHg for middle-elderly subjects. A primary reference for normal ankle SBP was suggested as 100-165 mmHg in the young and 110-170 mmHg in the middle-elderly subjects.

  3. The Relationship Between the Metabolic Syndrome and Systolic Inter-Arm Systolic Blood Pressure Difference in Korean Adults.

    Science.gov (United States)

    Yoon, Hyun; Choi, Seong Woo; Park, Jong; Ryu, So Yeon; Han, Mi Ah; Kim, Gwang Seok; Kim, Sung Gil; Oh, Hye Jong; Choi, Cheol Won

    2015-10-01

    The present study was conducted to assess the relationship between metabolic syndrome and systolic inter-arm blood pressure difference (sIAD) in Korean adults. This study included 410 adults (235 males, 175 females) who were over 30 years old and had undergone a health check from July to December in 2013. The incidence of high sIAD and metabolic syndrome were 23.4% and 23.2%, respectively. Key study results were as follows: First, the sIAD levels increased significantly with an increase in metabolic syndrome score (p<0.001), shown by sIAD levels after adjusted the variables that affect sIAD levels (age, gender, smoking, drinking, exercising, total cholesterol, and body mass index). These were 4.6±0.7 mmHg for metabolic syndrome score (MSS) 0; 5.8±0.5 mmHg for MSS 1; 6.2±0.6 mmHg for MSS 2, 9.2±0.8 mmHg for MSS 3; and 9.9±1.2 mmHg for MSS ≥4 (p<0.001). Second, the sIAD level of the metabolic syndrome group (9.3±0.7 mmHg) was significantly higher (p<0.001) than for the nonmetabolic syndrome group (5.7±0.3 mmHg). In conclusion, metabolic syndrome and an increased number of its components are associated with the sIAD levels in Korean adults.

  4. Two-phase flow and thermal response from nuclear excursions in tuff

    International Nuclear Information System (INIS)

    Rath, J.S.; Sanchez, L.C.; Taylor, L.L.

    1998-05-01

    Thermal hydrology calculations were performed to predict the geologic thermal and saturation response of a far-field nuclear criticality. The thermal hydrology (THX) calculations used an experimental version of a transient multi-phase fluid and energy simulator, BRAGFLO T. A total of 45 THX calculations were completed using various combinations of initial saturation S 0 , input heat generation zone (HGZ) radii r 0 , input energies E 0 , and input space power density functions (SPDFs). The thermal hydrology calculations were performed as a part the nuclear dynamics consequence analysis (NDCA) study for potential criticality consequences associated with disposal of high-level waste (HLW) and spent nuclear fuel (SNF) in an underground geologic repository. In the NDCA study it was identified that total fission energy E 0 , integrated from the power-time history, has an expected range of 10 17 --10 20 total fissions per excursion. This range of values is comparable to those reported for aqueous criticality accidents that had occurred in processing plants. The THX results show (using the conservative temperature recycle times) that a criticality frequency between 3 and 30 criticalities/yr is possible. Probability frequencies (generated by probabilistic risk analysis and the THX model) for these consequences indicate that any additional fissions are minor contributions to the biological hazards caused by the disposed fissile materials

  5. Hip strength and star excursion balance test deficits of patients with chronic ankle instability.

    Science.gov (United States)

    McCann, Ryan S; Crossett, Ian D; Terada, Masafumi; Kosik, Kyle B; Bolding, Brenn A; Gribble, Phillip A

    2017-11-01

    To examine isometric hip strength in those with and without CAI, and determine the degree of Star Excursion Balance Test (SEBT) variance explained by isometric hip strength. Single-blinded, cross-sectional, case-control study. Thirty individuals with CAI, 29 lateral ankle sprain (LAS) copers, and 26 healthy controls participated. We assessed dynamic postural control with the SEBT anterior (SEBT-ANT), posteromedial (SEBT-PM), and posterolateral (SEBT-PL) reaches, and isometric hip extension (EXT), abduction (ABD) and external rotation (ER) strength with hand-held dynamometry. The CAI and LAS coper groups' involved limbs and randomly selected limbs in controls were tested. Separate Kruskal-Wallis tests compared SEBT scores and isometric hip strength between groups. Backwards linear regression models determined the degree of SEBT variance explained by isometric hip strength. Statistical significance was set a priori at Phip strength compared to LAS copers and controls. Additionally, the CAI group's isometric hip strength significantly influenced dynamic postural control performance. Future CAI rehabilitation strategies should consider hip muscular strengthening to facilitate improvements in dynamic postural control. Copyright © 2017 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

  6. In search of mitochondrial mechanisms: interfield excursions between cell biology and biochemistry.

    Science.gov (United States)

    Bechtel, William; Abrahamsen, Adele

    2007-01-01

    Developing models of biological mechanisms, such as those involved in respiration in cells, often requires collaborative effort drawing upon techniques developed and information generated in different disciplines. Biochemists in the early decades of the 20th century uncovered all but the most elusive chemical operations involved in cellular respiration, but were unable to align the reaction pathways with particular structures in the cell. During the period 1940-1965 cell biology was emerging as a new discipline and made distinctive contributions to understanding the role of the mitochondrion and its component parts in cellular respiration. In particular, by developing techniques for localizing enzymes or enzyme systems in specific cellular components, cell biologists provided crucial information about the organized structures in which the biochemical reactions occurred. Although the idea that biochemical operations are intimately related to and depend on cell structures was at odds with the then-dominant emphasis on systems of soluble enzymes in biochemistry, a reconceptualization of energetic processes in the 1960s and 1970s made it clear why cell structure was critical to the biochemical account. This paper examines how numerous excursions between biochemistry and cell biology contributed a new understanding of the mechanism of cellular respiration.

  7. Fixed field alternating gradient accelerator with small orbit shift and tune excursion

    Directory of Open Access Journals (Sweden)

    Suzanne L. Sheehy

    2010-04-01

    Full Text Available A new design principle of a nonscaling fixed field alternating gradient accelerator is proposed. It is based on optics that produce approximate scaling properties. A large field index k is chosen to squeeze the orbit shift as much as possible by setting the betatron oscillation frequency in the second stability region of Hill’s equation. Then, the lattice magnets and their alignment are simplified. To simplify the magnets, we expand the field profile of r^{k} into multipoles and keep only a few lower order terms. A rectangular-shaped magnet is assumed with lines of constant field parallel to the magnet axis. The lattice employs a triplet of rectangular magnets for focusing, which are parallel to one another to simplify alignment. These simplifications along with fringe fields introduce finite chromaticity and the fixed field alternating gradient accelerator is no longer a scaling one. However, the tune excursion of the whole ring can be within half an integer and we avoid the crossing of strong resonances.

  8. Towards an Excursion Flora for Austria and all the Eastern Alps

    Directory of Open Access Journals (Sweden)

    Manfred A. Fischer

    2018-02-01

    Full Text Available This is on the one hand an announcement of the two-volume Fourth Edition of the Excursion Flora for Austria expanded by also including the remaining parts of the Eastern Alps (chapter 1, and on the other hand a rough survey of the flora of the Eastern Alps in connection with the main vegetation types (chapter 2. The geographical scope includes, besides Austria, the entire Eastern Alps from the Rhine valley in E Switzerland (Grisons to the Vipava valley in SW Slovenia. Volume 1 mainly contains comprehensive introductory chapters like introductions to plant morphology, taxonomy, and nomenclature, as well as a sketch of ecomorphology and habitat ecology, a survey of vegetation types (phytosociology and floristic peculiarities of the different natural regions, a rough history of floristic research, a detailed glossary including the meaning of epithets, etc., and drawings of several plant species characteristic of the flora covered. The structure of the keys concentrated in volume 2 is explained: besides the descriptive traits, they include for each taxon comprehensive ecological and plant geographical data, as well as information about Red Lists of the countries involved, plant uses, and taxonomical problems. Genus names are given not only in German, but also in the Romansh (Rumantsch Grischun, Italian, and Slovenian languages. In chapter 2, some important chorotypes including endemics are characterised, and an overview of floristic diversity (lists of exemplary taxa in accordance with the main and most characteristic vegetation types is presented.

  9. Star Excursion Balance Test Performance Varies by Sport in Healthy Division I Collegiate Athletes.

    Science.gov (United States)

    Stiffler, Mikel R; Sanfilippo, Jennifer L; Brooks, M Alison; Heiderscheit, Bryan C

    2015-10-01

    Cross-sectional. To describe performance and asymmetry on the Star Excursion Balance Test (SEBT) by sex and sport, and to determine if differences exist within a collegiate athlete population. Performance on the SEBT may differ between sexes and levels of competition, though the results of previous studies have been inconsistent. Investigation of performance and asymmetry differences between sports is limited. Sex- and sport-specific reference values likely need to be determined to best assess SEBT performance. Performance on the SEBT was retrospectively reviewed in 393 healthy National Collegiate Athletic Association Division I collegiate athletes from 8 sports. Means, standard deviations, and 95% confidence intervals were calculated for all variables. Normalized reach distance (percent limb length) and asymmetry between limbs were compared for the anterior (ANT), posterolateral (PL), and posteromedial (PM) directions and for the composite (COMP) score using a 2-way analysis of variance (ANOVA) of sex by sport, and a 1-way ANOVA to separately compare sports within each sex. Average normalized reach distance ranged from 62% to 69%, 84% to 97%, and 99% to 113% in the ANT, PL, and PM directions, respectively, and from 82% to 92% in the COMP score. Normalized asymmetry ranged from 3% to 4%, 5% to 8%, and 5% to 6% in the ANT, PL, and PM directions, respectively. A significant sex-by-sport interaction (P = .039) was observed in the ANT direction, with a sex effect for soccer players (Psport.

  10. Analysis of hypothetical nuclear excursions in the external core retention system

    International Nuclear Information System (INIS)

    Froehlich, R.; Kussmaul, G.; Schmuck, P.

    1976-01-01

    The core catcher system of the SNR 300 is outside the reactor tank. The probability of recriticality phenomena is reduced by its design, but the licensing procedures still call for the analysis of strong recriticality phenomena in the core catcher system outside the reactor tank in order to achieve a better understanding of the possible physical effects and to get to know the safety limits of the system. For their theoretical investigations, the authors used a two-partner model as presented in fig. 1. At the bottom of the core catcher - which consists of depleted UO 2 - there is a fuel cylinder. Another fuel cylinder (with the same axis) is dropped from a height of 250 cm. The two cylindrical masses are immersed in sodium, but a free fall is assumed since the possibility cannot be excluded that the reactor bottom may be empty or only partially filled with sodium. It was found that under these conditions the strongest excursions may be expected in those cases where prompt criticality does not occur until just before the two partners meet. (orig./AK) [de

  11. Accidental nuclear excursion recuplex operation 234-5 facility: Final medical report

    Energy Technology Data Exchange (ETDEWEB)

    Fuqua, P. A.

    1962-04-07

    The April 7, 1962 criticality accident involving human exposures was the first to have occurred in any production facility at Hanford. The accidental nuclear excursion did not result in any mechanical damage or spread of contamination. Three employees received over-exposure to gamma and neutron radiation. None were fatally exposed and in each case the over-exposure was recognized promptly. Following an initial period of medical observation and testing, the men were released to work. They continued to be followed clinically. Clinical studies performed were hematological procedures including leukocyte chromosome aberrations, morphologically aberrant blood cells, bone marrow evaluations, blood chemistry determinations, amino acid excretion studies, seminal fluid, urinary gonadotropins and estrogen excretion studies, testicular biopsies and crystalline lens examinations. These studies, along with a brief description of the accident and of the dosimetry, are summarized in this report by those participating in the studies. In view of the dose ranges received in these cases, both the negative and positive findings are considered to be of unusual interest due to the lack of knowledge of effects following human exposures at these levels.

  12. Concurrent validity of an automated algorithm for computing the center of pressure excursion index (CPEI).

    Science.gov (United States)

    Diaz, Michelle A; Gibbons, Mandi W; Song, Jinsup; Hillstrom, Howard J; Choe, Kersti H; Pasquale, Maria R

    2018-01-01

    Center of Pressure Excursion Index (CPEI), a parameter computed from the distribution of plantar pressures during stance phase of barefoot walking, has been used to assess dynamic foot function. The original custom program developed to calculate CPEI required the oversight of a user who could manually correct for certain exceptions to the computational rules. A new fully automatic program has been developed to calculate CPEI with an algorithm that accounts for these exceptions. The purpose of this paper is to compare resulting CPEI values computed by these two programs on plantar pressure data from both asymptomatic and pathologic subjects. If comparable, the new program offers significant benefits-reduced potential for variability due to rater discretion and faster CPEI calculation. CPEI values were calculated from barefoot plantar pressure distributions during comfortable paced walking on 61 healthy asymptomatic adults, 19 diabetic adults with moderate hallux valgus, and 13 adults with mild hallux valgus. Right foot data for each subject was analyzed with linear regression and a Bland-Altman plot. The automated algorithm yielded CPEI values that were linearly related to the original program (R 2 =0.99; Pcomputation methods. Results of this analysis suggest that the new automated algorithm may be used to calculate CPEI on both healthy and pathologic feet. Copyright © 2017 Elsevier B.V. All rights reserved.

  13. Habitat Demonstration Unit (HDU) Pressurized Excursion Module (PEM) Systems Integration Strategy

    Science.gov (United States)

    Gill, Tracy; Merbitz, Jerad; Kennedy, Kriss; Tri, Terry; Toups, Larry; Howe, A. Scott

    2011-01-01

    The Habitat Demonstration Unit (HDU) project team constructed an analog prototype lunar surface laboratory called the Pressurized Excursion Module (PEM). The prototype unit subsystems were integrated in a short amount of time, utilizing a rapid prototyping approach that brought together over 20 habitation-related technologies from a variety of NASA centers. This paper describes the system integration strategies and lessons learned, that allowed the PEM to be brought from paper design to working field prototype using a multi-center team. The system integration process was based on a rapid prototyping approach. Tailored design review and test and integration processes facilitated that approach. The use of collaboration tools including electronic tools as well as documentation enabled a geographically distributed team take a paper concept to an operational prototype in approximately one year. One of the major tools used in the integration strategy was a coordinated effort to accurately model all the subsystems using computer aided design (CAD), so conflicts were identified before physical components came together. A deliberate effort was made following the deployment of the HDU PEM for field operations to collect lessons learned to facilitate process improvement and inform the design of future flight or analog versions of habitat systems. Significant items within those lessons learned were limitations with the CAD integration approach and the impact of shell design on flexibility of placing systems within the HDU shell.

  14. Analysis of fission product release from HTGR core during transient temperature excursion

    International Nuclear Information System (INIS)

    Saito, Takao; Yamatoya, Naotoshi; Onuma, Mamoru

    1978-01-01

    The computer program ''FRANC'' was developed to calculate the release activity of fission products from a high-temperature gas cooled reactor (HTGR) core during transient temperature excursions such as a hypothetical loss of forced circulation combined with design basis depressurization. The program utilizes a segmented cylindrical core spatial model with the associated values of the prior fuel irradiation history and temperature conditions. The fission product transport and decay chain behavior is expressed by a set of differential equations. This set of equations describes the entire core inventory of fission products by means of calculated parameters based on the detailed spatial core conditions. The program determines the time-dependent amounts of fission product nuclides escaping from the core into the coolant. Coded in Continuous System Simulation Language (CSSL) with double precision, FRANC showed appropriate results for both short- and long-lived fission product nuclides. The sample calculation conducted by applying the program to a large HTGR indicated that it would take about one hour for noble gases and volatile nuclides to be released to the coolant, and several hours for metalic nuclides. (auth.)

  15. Scope Complexity Options Risks Excursions (SCORE) Version 3.0 Mathematical Description.

    Energy Technology Data Exchange (ETDEWEB)

    Gearhart, Jared Lee [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Samberson, Jonell Nicole [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Shettigar, Subhasini [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Jungels, John [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Welch, Kimberly M. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Jones, Dean A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-03-01

    The purpose of the Scope, Complexity, Options, Risks, Excursions (SCORE) model is to estimate the relative complexity of design variants of future warhead options. The results of this model allow those considering these options to understand the complexity tradeoffs between proposed warhead options. The core idea of SCORE is to divide a warhead option into a well- defined set of scope elements and then estimate the complexity of each scope element against a well understood reference system. The uncertainty associated with estimates can also be captured. A weighted summation of the relative complexity of each scope element is used to determine the total complexity of the proposed warhead option or portions of the warhead option (i.e., a National Work Breakdown Structure code). The SCORE analysis process is a growing multi-organizational Nuclear Security Enterprise (NSE) effort, under the management of the NA- 12 led Enterprise Modeling and Analysis Consortium (EMAC), that has provided the data elicitation, integration and computation needed to support the out-year Life Extension Program (LEP) cost estimates included in the Stockpile Stewardship Management Plan (SSMP).

  16. An Excursion Set Model of the Cosmic Web: the Abundance of Sheets, Filaments And Halos

    Energy Technology Data Exchange (ETDEWEB)

    Shen, Jiajian; /Penn State U., Astron. Astrophys.; Abel, Tom; /KIPAC, Menlo Park; Mo, Houjun; /Massachusetts U., Amherst; Sheth, Ravi; /Pennsylvania U.

    2006-01-11

    We discuss an analytic approach for modeling structure formation in sheets, filaments and knots. This is accomplished by combining models of triaxial collapse with the excursion set approach: sheets are defined as objects which have collapsed along only one axis, filaments have collapsed along two axes, and halos are objects in which triaxial collapse is complete. In the simplest version of this approach, which we develop here, large scale structure shows a clear hierarchy of morphologies: the mass in large-scale sheets is partitioned up among lower mass filaments, which themselves are made-up of still lower mass halos. Our approach provides analytic estimates of the mass fraction in sheets, filaments and halos, and its evolution, for any background cosmological model and any initial fluctuation spectrum. In the currently popular {Lambda}CDM model, our analysis suggests that more than 99% of the mass in sheets, and 72% of the mass in filaments, is stored in objects more massive than 10{sup 10}M{sub {circle_dot}} at the present time. For halos, this number is only 46%. Our approach also provides analytic estimates of how halo abundances at any given time correlate with the morphology of the surrounding large-scale structure, and how halo evolution correlates with the morphology of large scale structure.

  17. Sensitivity analysis of power excursion in RSG-GAS reactor due to reactivity insertion

    International Nuclear Information System (INIS)

    Pinem, Surian; Sembiring, Tagor Malem

    2002-01-01

    Reactor kinetics has a very important role in reactor operation safety and nuclear reactor control. One of the important aspects in reactor kinetics is power behavior as function of time due to chain reaction in the core. The calculation was performed using kinetic equation and feedback reactivity and evaluated using static power coefficient. Analysis was performed for oxide 250 g, silicide 250 g and silicide 300 g fuel elements with insertion of positive reactivity, negative reactivity and reactivity close to delay neutron fraction. The calculation of power excursion sensitivity showed that the insertion of 0,5 % Δk/k, in the fuel element of silicide 300 g is bigger 5 % than the one of oxide 250 g or silicide 250 g. If inserted by - 1,2 % Δk/k, there is no change among three fuel elements. Therefore, in kinetic point of view, it is showed there is no significant influence in the RSG-GAS reactor operation safety is the current core of oxide 250 g is converted to silicide 250 g or to silicide 300 g

  18. Excursions out-of-lane versus standard deviation of lateral position as outcome measure of the on-the-road driving test.

    Science.gov (United States)

    Verster, Joris C; Roth, Thomas

    2014-07-01

    The traditional outcome measure of the Dutch on-the-road driving test is the standard deviation of lateral position (SDLP), the weaving of the car. This paper explores whether excursions out-of-lane are a suitable additional outcome measure to index driving impairment. A literature search was conducted to search for driving tests that used both SDLP and excursions out-of-lane as outcome measures. The analyses were limited to studies examining hypnotic drugs because several of these drugs have been shown to produce next-morning sedation. Standard deviation of lateral position was more sensitive in demonstrating driving impairment. In fact, solely relying on excursions out-of-lane as outcome measure incorrectly classifies approximately half of impaired drives as unimpaired. The frequency of excursions out-of-lane is determined by the mean lateral position within the right traffic lane. Defining driving impairment as having a ΔSDLP > 2.4 cm, half of the impaired driving tests (51.2%, 43/84) failed to produce excursions out-of-lane. Alternatively, 20.9% of driving tests with ΔSDLP < 2.4 cm (27/129) had at least one excursion out-of-lane. Excursions out-of-lane are neither a suitable measure to demonstrate driving impairment nor is this measure sufficiently sensitive to differentiate adequately between differences in magnitude of driving impairment. Copyright © 2014 John Wiley & Sons, Ltd.

  19. Reliability and feasibility of gait initiation centre-of-pressure excursions using a Wii® Balance Board in older adults at risk of falling.

    Science.gov (United States)

    Lee, James; Webb, Graham; Shortland, Adam P; Edwards, Rebecca; Wilce, Charlotte; Jones, Gareth D

    2018-04-17

    Impairments in dynamic balance have a detrimental effect in older adults at risk of falls (OARF). Gait initiation (GI) is a challenging transitional movement. Centre of pressure (COP) excursions using force plates have been used to measure GI performance. The Nintendo Wii Balance Board (WBB) offers an alternative to a standard force plate for the measurement of CoP excursion. To determine the reliability of COP excursions using the WBB, and its feasibility within a 4-week strength and balance intervention (SBI) treating OARF. Ten OARF subjects attending SBI and ten young healthy adults, each performed three GI trials after 10 s of quiet stance from a standardised foot position (shoulder width) before walking forward 3 m to pick up an object. Averaged COP mediolateral (ML) and anteroposterior (AP) excursions (distance) and path-length time (GI-onset to first toe-off) were analysed. WBB ML (0.866) and AP COP excursion (0.895) reliability (ICC 3,1 ) was excellent, and COP path-length reliability was fair (0.517). Compared to OARF, healthy subjects presented with larger COP excursion in both directions and shorter COP path length. OARF subjects meaningfully improved their timed-up-and-go and ML COP excursion between weeks 1-4, while AP COP excursions, path length, and confidence-in-balance remained stable. COP path length and excursion directions probably measure different GI postural control attributes. Limitations in WBB accuracy and precision in transition tasks needs to be established before it can be used clinically to measure postural aspects of GI viably. The WBB could provide valuable clinical evaluation of balance function in OARF.

  20. Hydrodynamics of planing monohull watercraft

    CERN Document Server

    Vorus, William S

    2017-01-01

    This book addresses the principles involved in the design and engineering of planing monohull power boats, with an emphasis on the theoretical fundamentals that readers need in order to be fully functional in marine design and engineering. Author William Vorus focuses on three topics: boat resistance, seaway response, and propulsion and explains the physical principles, mathematical details, and theoretical details that support physical understanding. In particular, he explains the approximations and simplifications in mathematics that lead to success in the applications of planing craft design engineering, and begins with the simplest configuration that embodies the basic physics. He leads readers, step-by-step, through the physical complications that occur, leading to a useful working knowledge of marine design and engineering. Included in the book are a wealth of examples that exemplify some of the most important naval architecture and marine engineering problems that challenge many of today’s engineers.

  1. Plane waves with weak singularities

    International Nuclear Information System (INIS)

    David, Justin R.

    2003-03-01

    We study a class of time dependent solutions of the vacuum Einstein equations which are plane waves with weak null singularities. This singularity is weak in the sense that though the tidal forces diverge at the singularity, the rate of divergence is such that the distortion suffered by a freely falling observer remains finite. Among such weak singular plane waves there is a sub-class which does not exhibit large back reaction in the presence of test scalar probes. String propagation in these backgrounds is smooth and there is a natural way to continue the metric beyond the singularity. This continued metric admits string propagation without the string becoming infinitely excited. We construct a one parameter family of smooth metrics which are at a finite distance in the space of metrics from the extended metric and a well defined operator in the string sigma model which resolves the singularity. (author)

  2. The museum “La casa encantada” of Briones in the teaching of history: proposed primary education school excursion

    Directory of Open Access Journals (Sweden)

    Sebastián Molina Puche

    2013-05-01

    Full Text Available It has been demonstrated, in order that the school excursions develop all his didactic potential (this is, in order that they serve to stimulate the “guided discovery” learning, have to be framed in didactic itineraries and with it, to be considered as an integral part of the didactic programming of the course. The curricular integration of the school excursions is one of the principal problems which the teacher meets at the moment of putting in practical this important didactic resource. With this work we claim, beside showing many possibilities that there has the museum of “The Enchanted House” of Briones (section ethnology of the Museum of La Rioja for the learning of the history in Primary Education, to indicate how they can integrate in the curriculum the visits to the museum in each of three cycles that shape this educational level.

  3. Functional Aesthetic Occlusal Plane (FAOP)

    OpenAIRE

    Câmara, Carlos Alexandre; Martins, Renato Parsekian

    2016-01-01

    ABSTRACT Introduction: A reasonable exposure of incisors and gingival tissues is generally considered more attractive than excess or lack of exposure. A reasonable gingival exposure is considered to be around 0 to 2 mm when smiling and 2-4 mm exposure of the maxillary incisor edge when the lips are at rest. Objective: The aim of this paper is to present the Functional Aesthetic Occlusal Plane (FAOP), which aims to help in the diagnosis of the relationships established among molars, incisors...

  4. [Development of an automatic pneumatic tourniquet system that determines pressures in synchrony with systolic blood pressure].

    Science.gov (United States)

    Liu, Hongyun; Li, Kaiyuan; Zhang, Zhengbo; Guo, Junyan; Wang, Weidong

    2012-11-01

    The correlation coefficients between arterial occlusion pressure and systolic blood pressure, diastolic blood pressure, limb circumference, body mass etc were obtained through healthy volunteer experiments, in which tourniquet were applied on upper/lower extremities. The prediction equations were derived from the data of experiments by multiple regression analysis. Based on the microprocessor C8051F340, a new pneumatic tourniquet system that can determine tourniquet pressure in synchrony with systolic blood pressure was developed and verified the function and stability of designed system. Results showed that the pneumatic tourniquet which automatically adjusts occlusion pressure in accordance with systolic blood pressure could stop the flow of blood to get a bloodless field.

  5. Plane waves and spacelike infinity

    International Nuclear Information System (INIS)

    Marolf, Donald; Ross, Simon F

    2003-01-01

    In an earlier paper, we showed that the causal boundary of any homogeneous plane wave satisfying the null convergence condition consists of a single null curve. In Einstein-Hilbert gravity, this would include any homogeneous plane wave satisfying the weak null energy condition. For conformally flat plane waves such as the Penrose limit of AdS 5 x S 5 , all spacelike curves that reach infinity also end on this boundary and the completion is Hausdorff. However, the more generic case (including, e.g., the Penrose limits of AdS 4 x S 7 and AdS 7 x S 4 ) is more complicated. In one natural topology, not all spacelike curves have limit points in the causal completion, indicating the need to introduce additional points at 'spacelike infinity' - the endpoints of spacelike curves. We classify the distinct ways in which spacelike curves can approach infinity, finding a two-dimensional set of distinct limits. The dimensionality of the set of points at spacelike infinity is not, however, fixed from this argument. In an alternative topology, the causal completion is already compact, but the completion is non-Hausdorff

  6. Effects of numerical dissipation and unphysical excursions on scalar-mixing estimates in large-eddy simulations

    Science.gov (United States)

    Sharan, Nek; Matheou, Georgios; Dimotakis, Paul

    2017-11-01

    Artificial numerical dissipation decreases dispersive oscillations and can play a key role in mitigating unphysical scalar excursions in large eddy simulations (LES). Its influence on scalar mixing can be assessed through the resolved-scale scalar, Z , its probability density function (PDF), variance, spectra, and the budget of the horizontally averaged equation for Z2. LES of incompressible temporally evolving shear flow enabled us to study the influence of numerical dissipation on unphysical scalar excursions and mixing estimates. Flows with different mixing behavior, with both marching and non-marching scalar PDFs, are studied. Scalar fields for each flow are compared for different grid resolutions and numerical scalar-convection term schemes. As expected, increasing numerical dissipation enhances scalar mixing in the development stage of shear flow characterized by organized large-scale pairings with a non-marching PDF, but has little influence in the self-similar stage of flows with marching PDFs. Flow parameters and regimes sensitive to numerical dissipation help identify approaches to mitigate unphysical excursions while minimizing dissipation.

  7. Shared Responsibility for Type 1 Diabetes Care Is Associated With Glycemic Variability and Risk of Glycemic Excursions in Youth.

    Science.gov (United States)

    Marker, Arwen M; Noser, Amy E; Clements, Mark A; Patton, Susana R

    2018-01-01

    We examined how parent and youth responsibility for type 1 diabetes (T1D) care is related to adherence and glycemic outcomes, namely, glycemic variability and risk of glycemic excursions. One hundred thirty-five parent-youth dyads (10-16 years old; diagnosed with T1D for at least 6 months) participated in this study. Percent responsibility of T1D care attributed to the youth, parent, or shared was measured using the Diabetes Family Responsibility Questionnaire. We collected youth's hemoglobin A1c (HbA1c) and glucometer downloads to examine relationships between responsibility and HbA1c, frequency of blood glucose monitoring (self-monitoring blood glucose, SMBG), risk of glycemic excursions, and actual glycemic variability using bivariate correlations and path analysis. Participants reported shared responsibility for almost half of T1D self-care tasks. Bivariate correlations showed shared responsibility was associated with less variability, whereas parent responsibility was associated with greater glycemic variability and risk for glycemic excursions. Youth responsibility was associated with lower frequency of SMBG. The path analyses confirmed our correlational findings (pshypothesis that shared T1D responsibility is associated with better diabetes outcomes in youth. © The Author 2017. Published by Oxford University Press on behalf of the Society of Pediatric Psychology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

  8. Are U-channels measurements appropriate for reversal or excursion records ?

    Science.gov (United States)

    Philippe, E. G. H.; Valet, J. P.

    2017-12-01

    Sampling of sediment cores by U-channel plastic tubes is a very successful technique that allows to perform measurements of the magnetic remanence and demagnetization of long sections of sediment. This approach made possible the acquisition of detailed records of paleosecular variation, geomagnetic polarity and relative paleointensity over the past million years and yielded significant advances in our knowledge of the geomagnetic field changes. The major pitfall is that the resolution of the signal which is imposed by the deposition rate of the sediment is also attenuated by the response curve of the magnetic sensors used for measurements. This is not so critical to document the dipole field changes, but may have a significant impact to recover fast field changes typical of the non-dipole field that prevail during reversals and excursions. We have investigated possible consequences by comparing 150 successive individual directions of 1 cm side successive single samples with the measurement of the 1.5m equivalent U-channel obtained by placing the same samples adjacent to each other. We compared different transition lengths and generated transitional directions that produce records with similar characteristics as those derived from volcanic records of reversals with a magnetization intensity dropping to 5% of the full polarity value during the transition. The results show that even with transitional intervals as long as 30 cm and therefore associated with deposition rates as high as 10 cm/ka the U-channels considerably smooth all variations with significant consequences on the VGP paths that become more constrained in longitude. Despite little similarity with the global structure of the transition, the U-channels fail to reproduce the complexity of the transitional period. The transitional VGPs never duplicate the variations of the non-dipole field even within several centimeters and generate artificial clusters or periods of apparent fast changes. We are currently

  9. Study of the thermal and hydraulic phenomena occurring during power excursion on a heated test section

    International Nuclear Information System (INIS)

    Nyer, M.

    1969-01-01

    The thermal and hydrodynamic phenomena occurring during a power excursion were studied in an out-of-pile loop with a water cooled channel at low pressure (1 to 4 atm. abs. ). Circular and rectangular test sections with electrically heated walls of two different thermal diffusivity materials(aluminium and stainless steel) were used. The rectangular test sections were 600 mm long, 35 mm wide and had a 2, 9 mm gap; they simulate two half plates of the M.T.R. fuel element. Natural or forced convection are possible in the test section; the water height above it can be varied from 2.8 to 8 meters and the maximum allowed pressure at its outlet is 4 atm. abs.The heating source is a series of lead batteries which is able to generate, for short periods of time, 85 volts and 25000 amperes; linear, square or exponential power rise versus time can be realized. A 14 channels tape recorder (0-10 000 Hz bandwidth; is used for the measurements of temperature (8/100 mm diameter thermocouple), pressure ('Statham' pressure transducers) and void fraction (X rays). More than 500 tests have been carried out. The influence of the initial water temperature, flow rate, pressure, water height on the water ejections, pressure variations and void fraction in the test section were studied. Tests with energies up to 3000 W/cm in 50 milliseconds were attempted. The energy above which the instabilities appear was determined. An interpretation of the observed phenomena and a simplified theoretical model are presented [fr

  10. Environmental forcing of terrestrial carbon isotope excursion amplification across five Eocene hyperthermals

    Science.gov (United States)

    Bowen, G. J.; Abels, H.

    2015-12-01

    Abrupt changes in the isotope composition of exogenic carbon pools accompany many major episodes of global change in the geologic record. The global expression of this change in substrates that reflect multiple carbon pools provides important evidence that many events reflect persistent, global redistribution of carbon between reduced and oxidized stocks. As the diversity of records documenting any event grows, however, discrepancies in the expression of carbon isotope change among substrates are almost always revealed. These differences in magnitude, pace, and pattern of change can complicate interpretations of global carbon redistribution, but under ideal circumstances can also provide additional information on changes in specific environmental and biogeochemical systems that accompanied the global events. Here we evaluate possible environmental influences on new terrestrial records of the negative carbon isotope excursions (CIEs) associated with multiple hyperthermals of the Early Eocene, which show a common pattern of amplified carbon isotope change in terrestrial paleosol carbonate records relative to that recorded in marine substrates. Scaling relationships between climate and carbon-cycle proxies suggest that that the climatic (temperature) impact of each event scaled proportionally with the magnitude of its marine CIE, likely implying that all events involved release of reduced carbon with a similar isotopic composition. Amplification of the terrestrial CIEs, however, does not scale with event magnitude, being proportionally less for the first, largest event (the PETM). We conduct a sensitivity test of a coupled plant-soil carbon isotope model to identify conditions that could account for the observed CIE scaling. At least two possibilities consistent with independent lines of evidence emerge: first, varying effects of pCO2 change on photosynthetic carbon isotope discrimination under changing background pCO2, and second, contrasting changes in regional

  11. Systolic time intervals vs invasive predictors of fluid responsiveness after coronary artery bypass surgery(dagger)

    NARCIS (Netherlands)

    Smorenberg, A.; Lust, E.J.; Beishuizen, A.; Meijer, J.H.; Verdaasdonk, R.M.; Groeneveld, A.B.J.

    2013-01-01

    OBJECTIVES: Haemodynamic parameters for predicting fluid responsiveness in intensive care patients are invasive, technically challenging or not universally applicable. We compared the initial systolic time interval (ISTI), a non-invasive measure of the time interval between the electrical and

  12. The systolic blood pressure difference between arms and cardiovascular disease in the Framingham Heart Study.

    Science.gov (United States)

    Weinberg, Ido; Gona, Philimon; O'Donnell, Christopher J; Jaff, Michael R; Murabito, Joanne M

    2014-03-01

    An increased interarm systolic blood pressure difference is an easily determined physical examination finding. The relationship between interarm systolic blood pressure difference and risk of future cardiovascular disease is uncertain. We described the prevalence and risk factor correlates of interarm systolic blood pressure difference in the Framingham Heart Study (FHS) original and offspring cohorts and examined the association between interarm systolic blood pressure difference and incident cardiovascular disease and all-cause mortality. An increased interarm systolic blood pressure difference was defined as ≥ 10 mm Hg using the average of initial and repeat blood pressure measurements obtained in both arms. Participants were followed through 2010 for incident cardiovascular disease events. Multivariable Cox proportional hazards regression analyses were performed to investigate the effect of interarm systolic blood pressure difference on incident cardiovascular disease. We examined 3390 (56.3% female) participants aged 40 years and older, free of cardiovascular disease at baseline, mean age of 61.1 years, who attended a FHS examination between 1991 and 1994 (original cohort) and from 1995 to 1998 (offspring cohort). The mean absolute interarm systolic blood pressure difference was 4.6 mm Hg (range 0-78). Increased interarm systolic blood pressure difference was present in 317 (9.4%) participants. The median follow-up time was 13.3 years, during which time 598 participants (17.6%) experienced a first cardiovascular event, including 83 (26.2%) participants with interarm systolic blood pressure difference ≥ 10 mm Hg. Compared with those with normal interarm systolic blood pressure difference, participants with an elevated interarm systolic blood pressure difference were older (63.0 years vs 60.9 years), had a greater prevalence of diabetes mellitus (13.3% vs 7.5%,), higher systolic blood pressure (136.3 mm Hg vs 129.3 mm Hg), and a higher total cholesterol

  13. Safety and effect of high dose allopurinol in patients with severe left ventricular systolic dysfunction

    Directory of Open Access Journals (Sweden)

    Mohammad Mostafa Ansari-Ramandi

    2017-06-01

    Conclusion: Allopurinol could be of benefit in non-hyperuricemic patients with severe LV systolic dysfunction without significant adverse effects. Randomized clinical trials are needed in future to confirm the results.

  14. THE HALO MASS FUNCTION FROM EXCURSION SET THEORY. I. GAUSSIAN FLUCTUATIONS WITH NON-MARKOVIAN DEPENDENCE ON THE SMOOTHING SCALE

    International Nuclear Information System (INIS)

    Maggiore, Michele; Riotto, Antonio

    2010-01-01

    A classic method for computing the mass function of dark matter halos is provided by excursion set theory, where density perturbations evolve stochastically with the smoothing scale, and the problem of computing the probability of halo formation is mapped into the so-called first-passage time problem in the presence of a barrier. While the full dynamical complexity of halo formation can only be revealed through N-body simulations, excursion set theory provides a simple analytic framework for understanding various aspects of this complex process. In this series of papers we propose improvements of both technical and conceptual aspects of excursion set theory, and we explore up to which point the method can reproduce quantitatively the data from N-body simulations. In Paper I of the series, we show how to derive excursion set theory from a path integral formulation. This allows us both to derive rigorously the absorbing barrier boundary condition, that in the usual formulation is just postulated, and to deal analytically with the non-Markovian nature of the random walk. Such a non-Markovian dynamics inevitably enters when either the density is smoothed with filters such as the top-hat filter in coordinate space (which is the only filter associated with a well-defined halo mass) or when one considers non-Gaussian fluctuations. In these cases, beside 'Markovian' terms, we find 'memory' terms that reflect the non-Markovianity of the evolution with the smoothing scale. We develop a general formalism for evaluating perturbatively these non-Markovian corrections, and in this paper we perform explicitly the computation of the halo mass function for Gaussian fluctuations, to first order in the non-Markovian corrections due to the use of a top-hat filter in coordinate space. In Paper II of this series we propose to extend excursion set theory by treating the critical threshold for collapse as a stochastic variable, which better captures some of the dynamical complexity of the

  15. Morphology of the Iceland Basin Excursion from a spherical harmonics analysis and an iterative Bayesian inversion procedure of sedimentary records

    Science.gov (United States)

    Lanci, Luca; Kissel, Catherine; Leonhardt, Roman; Laj, Carlo

    2008-08-01

    Based on 5 published marine high-resolution sedimentary records of the Iceland Basin Excursion [IBE; Channell, J.E.T., Hodell, D.A., Lehman, B., 1997. Relative geomagnetic paleointensity and ∂ 18O at ODP Site 983/Gardar Drift, North Atlantic since 350 ka. Earth Planet. Sci. Lett. 153, 103-118; Laj, C., Kissel, C., Roberts, A., 2006. Geomagnetic field behavior during the Iceland Basin and Laschamp geomagnetic excursions: a simple transitional field geometry? Geochem. Geophys. Geosystems. 7, Q03004, doi:10.1029/2005GC001122] dated around 186-190 kyr, we present models of the excursional geomagnetic field at the Earth's surface using two different approaches. First a spherical harmonics analysis is performed after synchronization of the records using their paleointensity profiles. Second, we have used an iterative Bayesian inversion procedure, calibrated using the single volcanic data available so far. Both modeling approaches suffer from imperfections of the paleomagnetic signals and mostly from the still poor geographical distribution of detailed records, presently available only from the North Atlantic and the West Pacific. For these reasons, our modeling results should only be regarded as preliminary models of the geomagnetic field during the IBE, susceptible to improvements when including results from future paleomagnetic studies. Nevertheless, both approaches show distinct similarities and are stable against moderate variations of modeling parameters. The general picture is that of a dipole field undergoing a strong reduction, but remaining higher than the non-dipole field all through the excursional process, except for a very short interval of time corresponding to the dipole minimum at the center of the excursion. On the other hand, some differences exist between the results of the two models with each other and with the real data when the virtual geomagnetic pole (VGP) paths are considered. The non-dipole field does not appear to undergo very significant

  16. Some Considerations Regarding Plane to Plane Parallelism Error Effects in Robotic Systems

    Directory of Open Access Journals (Sweden)

    Stelian Alaci

    2015-06-01

    Full Text Available The paper shows that by imposing the parallelism constraint between the measured plane and the reference plane, the position of the current plane is not univocal specified and is impossible to specify the way to attain the parallelism errors imposed by accuracy constrains. The parameters involved in the calculus of plane to plane parallelism error can be used to set univocal the relative position between the two planes.

  17. Civil and Patriotic Education of Students by Means of Excursion Activities in Russia in the Second Half of XIX – Early XX Centuries

    Directory of Open Access Journals (Sweden)

    Nadezhda V. Tarasova

    2014-06-01

    Full Text Available The article is concerned with the problem of civil and patriotic education of students by means of voluntary activity, presents historical and educational analysis of excursion activities as one of the major forms of volunteer work of schoolchildren in Russia in the second half of the XIX – early XX centuries, determines its major goals and objectives. The paper, using archive data, attempts to consider excursion activity as one of the major forms of volunteer work, promoting patriotism development in rising generation. The opinions of innovative teachers of the examined period, who considered that excursions had great educational potential are characterized. The position of the Ministry of Education, concerning educational potential of excursions is examined.

  18. Work Planing Automation at Mechanical Subdivision

    OpenAIRE

    Dzindzelėta, Vytautas

    2005-01-01

    Work planing automation, installation possibilities and future outlook at mechanical subdivision. To study how the work planing has changed before and after automation process and to analyse automation process methodology.

  19. Combinatorial geometry in the plane

    CERN Document Server

    Hadwiger, Hugo; Klee, Victor

    2014-01-01

    Geared toward advanced undergraduates familiar with analysis and college geometry, this concise book discusses theorems on topics restricted to the plane such as convexity, coverings, and graphs. In addition to helping students cultivate rigorous thought, the text encourages the development of mathematical intuition and clarifies the nature of mathematical research.The two-part treatment begins with specific topics including integral distances, covering problems, point set geometry and convexity, simple paradoxes involving point sets, and pure combinatorics, among other subjects. The second pa

  20. SNAP Satellite Focal Plane Development

    International Nuclear Information System (INIS)

    Bebek, C.; Akerlof, C.; Aldering, G.; Amanullah, R.; Astier, P.; Baltay, C.; Barrelet, E.; Basa, S.; Bercovitz, J.; Bergstrom, L.; Berstein, G.P.; Bester, M.; Bohlin, R.; Bonissent, A.; Bower, C.; Campbell, M.; Carithers, W.; Commins, E.; Day, C.; Deustua, S.; DiGennaro, R.; Ealet, A.; Ellis, R.; Emmett, W.; Eriksson, M.; Fouchez, D.; Fruchter, A.; Genat, J-F.; Goldhaber, G.; Goobar, A.; Groom, D.; Heetderks, H.; Holland, S.; Huterer, D.; Johnson, W.; Kadel, R.; Karcher, A.; Kim, A.; Kolbe, W.; Lafever, R.; Lamoureaux, J.; Lampton, M.; Lefevre, O.; Levi, M.; Levin, D.; Linder, E.; Loken, S.; Malina, R.; Mazure, A.; McKay, T.; McKee, S.; Miquel, R.; Morgan, N.; Mortsell, E.; Mostek, N.; Mufson, S.; Musser, J.; Roe, N.; Nugent, P.; Oluseyi, H.; Pain, R.; Palaio, N.; Pankow, D.; Perlmutter, S.; Prieto, E.; Rabinowitz, D.; Refregier, A.; Rhodes, J.; Schubnell, M.; Sholl, M.; Smadja, G.; Smith, R.; Smoot, G.; Snyder, J.; Spadafora, A.; Szymkowiak, A.; Tarle, G.; Taylor, K.; Tilquin, A.; Tomasch, A.; Vincent, D.; von der Lippe, H.; Walder, J-P.; Wang, G.

    2003-01-01

    The proposed SuperNova/Acceleration Probe (SNAP) mission will have a two-meter class telescope delivering diffraction-limited images to an instrumented 0.7 square degree field in the visible and near-infrared wavelength regime. The requirements for the instrument suite and the present configuration of the focal plane concept are presented. A two year R and D phase, largely supported by the Department of Energy, is just beginning. We describe the development activities that are taking place to advance our preparedness for mission proposal in the areas of detectors and electronics

  1. Transversus abdominis plane block for an emergency laparotomy in a high-risk, elderly patient

    Directory of Open Access Journals (Sweden)

    Surekha S Patil

    2010-01-01

    Full Text Available A 72-year-old male patient with gall bladder perforation and small intestinal obstruction from impacted gall stone was posted for emergency laparotomy. He had congestive heart failure, severe hypertension at admission and history of multiple other coexisting diseases. On admission, he developed pulmonary oedema from systolic hypertension which was controlled by ventilatory support, nitroglycerine and furosemide. Preoperative international normalized ratio was 2.34 and left ventricular ejection fraction was only 20%. Because of risk of exaggerated fall in blood pressure during induction of anaesthesia (general or neuraxial, a transversus abdominis plane block via combined Petit triangle and subcostal technique was administered and supplemented with Propofol sedation.

  2. Comparison of longitudinal excursion of a nerve-phantom model using quantitative ultrasound imaging and motion analysis system methods: A convergent validity study.

    Science.gov (United States)

    Paquette, Philippe; El Khamlichi, Youssef; Lamontagne, Martin; Higgins, Johanne; Gagnon, Dany H

    2017-08-01

    Quantitative ultrasound imaging is gaining popularity in research and clinical settings to measure the neuromechanical properties of the peripheral nerves such as their capability to glide in response to body segment movement. Increasing evidence suggests that impaired median nerve longitudinal excursion is associated with carpal tunnel syndrome. To date, psychometric properties of longitudinal nerve excursion measurements using quantitative ultrasound imaging have not been extensively investigated. This study investigates the convergent validity of the longitudinal nerve excursion by comparing measures obtained using quantitative ultrasound imaging with those determined with a motion analysis system. A 38-cm long rigid nerve-phantom model was used to assess the longitudinal excursion in a laboratory environment. The nerve-phantom model, immersed in a 20-cm deep container filled with a gelatin-based solution, was moved 20 times using a linear forward and backward motion. Three light-emitting diodes were used to record nerve-phantom excursion with a motion analysis system, while a 5-cm linear transducer allowed simultaneous recording via ultrasound imaging. Both measurement techniques yielded excellent association ( r  = 0.99) and agreement (mean absolute difference between methods = 0.85 mm; mean relative difference between methods = 7.48 %). Small discrepancies were largely found when larger excursions (i.e. > 10 mm) were performed, revealing slight underestimation of the excursion by the ultrasound imaging analysis software. Quantitative ultrasound imaging is an accurate method to assess the longitudinal excursion of an in vitro nerve-phantom model and appears relevant for future research protocols investigating the neuromechanical properties of the peripheral nerves.

  3. Author Correction: Reliability and feasibility of gait initiation centre-of-pressure excursions using a Wii® Balance Board in older adults at risk of falling.

    Science.gov (United States)

    Lee, James; Webb, Graham; Shortland, Adam P; Edwards, Rebecca; Wilce, Charlotte; Jones, Gareth D

    2018-05-12

    In the original publication, the article title was incorrectly published as 'Reliability and feasibility of gait initiation centre-of-pressure excursions using a Wii® Balance Board in older adults at risk of failing'. The correct title should read as 'Reliability and feasibility of gait initiation centre-of-pressure excursions using a Wii® Balance Board in older adults at risk of falling'.

  4. 2D-speckle tracking right ventricular strain to assess right ventricular systolic function in systolic heart failure. Analysis of the right ventricular free and posterolateral walls.

    Science.gov (United States)

    Mouton, Stéphanie; Ridon, Héléne; Fertin, Marie; Pentiah, Anju Duva; Goémine, Céline; Petyt, Grégory; Lamblin, Nicolas; Coisne, Augustin; Foucher-Hossein, Claude; Montaigne, David; de Groote, Pascal

    2017-10-15

    Right ventricular (RV) systolic function is a powerful prognostic factor in patients with systolic heart failure. The accurate estimation of RV function remains difficult. The aim of the study was to determine the diagnostic accuracy of 2D-speckle tracking RV strain in patients with systolic heart failure, analyzing both free and posterolateral walls. Seventy-six patients with dilated cardiopathy (left ventricular end-diastolic volume≥75ml/m 2 ) and left ventricular ejection fraction≤45% had an analysis of the RV strain. Feasibility, reproducibility and diagnostic accuracy of RV strain were analyzed and compared to other echocardiographic parameters of RV function. RV dysfunction was defined as a RV ejection fraction≤40% measured by radionuclide angiography. RV strain feasibility was 93.9% for the free-wall and 79.8% for the posterolateral wall. RV strain reproducibility was good (intra-observer and inter-observer bias and limits of agreement of 0.16±1.2% [-2.2-2.5] and 0.84±2.4 [-5.5-3.8], respectively). Patients with left heart failure have a RV systolic dysfunction that can be unmasked by advanced echocardiographic imaging: mean RV strain was -21±5.7% in patients without RV dysfunction and -15.8±5.1% in patients with RV dysfunction (p=0.0001). Mean RV strain showed the highest diagnostic accuracy to predict depressed RVEF (area under the curve (AUC) 0.75) with moderate sensitivity (60.5%) but high specificity (87.5%) using a cutoff value of -16%. RV strain seems to be a promising and more efficient measure than previous RV echocardiographic parameters for the diagnosis of RV systolic dysfunction. Copyright © 2017 Elsevier B.V. All rights reserved.

  5. Carbon isotopic record from Upper Devonian carbonates at Dongcun in Guilin, southern China, supporting the world-wide pattern of carbon isotope excursions during Frasnian-Famennian transition

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    Two positive δ13C excursions are presented in records from the Frasnian-Famennian (F-F) marine carbonate sediments in Europe, America, Africa, and Australia, having been considered as a worldwide pattern, and attributed to enhanced organic carbon burial during the F-F biological mass extinction. However, this worldwide pattern has not been revealed from the well-deposited Late Devonian sequences in southern China. In this paper, a detailed investigation has been made on the Late Devonian section at Dongcun, Guilin, southern China to constrain perturbations in δ13C of carbonates in the F-F deposited sequence. The result from this section also indicates two positive δ13C excursions during the F-F transition. The first excursion with an amplitude of 1.5‰ occurred at the bottom of linguiformis Zone, later than the early excursion existing in the Late rhenana Zone of the Late Devonian profiles in other continents, especially, in central Europe. This difference has been expected to be a result as conodont Palmatolepis linguiformis occurred earlier in southern China than other sites. The second excursion with an amplitude of 2.1‰ is located at the F-F boundary, same as the records from other continents. This result strongly supports the view that two carbon isotope positive excursions during the F-F transition are common in carbonate sediments, resulting from worldwide increases of organic carbon burial intensity.

  6. Free gracilis transfer for smile in children: the Massachusetts Eye and Ear Infirmary Experience in excursion and quality-of-life changes.

    Science.gov (United States)

    Hadlock, Tessa A; Malo, Juan S; Cheney, Mack L; Henstrom, Douglas K

    2011-01-01

    Free muscle transfer for facial reanimation has become the standard of care in recent decades and is now the cornerstone intervention for dynamic smile reanimation. We sought to quantify smile excursion and quality-of-life (QOL) changes in our pediatric free gracilis recipients following reanimation. We quantified gracilis muscle excursion in 17 pediatric patients undergoing 19 consecutive pediatric free gracilis transplantation operations, using our validated SMILE program, as an objective measure of functional outcome. These were compared against excursion measured the same way in a cohort of 17 adults with 19 free gracilis operations. In addition, we prospectively evaluated QOL outcomes in these children using the Facial Clinimetric Evaluation (FaCE) instrument. The mean gracilis excursion in our pediatric free gracilis recipients was 8.8 mm ± 5.0 mm, which matched adult results, but with fewer complete failures of less than 2-mm excursion, with 2 (11%) and 4 (21%), respectively. Quality-of-life measures indicated statistically significant improvements following dynamic smile reanimation (P = .01). Dynamic facial reanimation using free gracilis transfer in children has an acceptable success rate, yields improved commissure excursion, and improves QOL in the pediatric population. It should be considered first-line therapy for children with lack of a meaningful smile secondary to facial paralysis.

  7. Cinnamon extract inhibits α-glucosidase activity and dampens postprandial glucose excursion in diabetic rats

    Science.gov (United States)

    2011-01-01

    Background α-glucosidase inhibitors regulate postprandial hyperglycemia (PPHG) by impeding the rate of carbohydrate digestion in the small intestine and thereby hampering the diet associated acute glucose excursion. PPHG is a major risk factor for diabetic vascular complications leading to disabilities and mortality in diabetics. Cinnamomum zeylanicum, a spice, has been used in traditional medicine for treating diabetes. In this study we have evaluated the α-glucosidase inhibitory potential of cinnamon extract to control postprandial blood glucose level in maltose, sucrose loaded STZ induced diabetic rats. Methods The methanol extract of cinnamon bark was prepared by Soxhlet extraction. Phytochemical analysis was performed to find the major class of compounds present in the extract. The inhibitory effect of cinnamon extract on yeast α-glucosidase and rat-intestinal α-glucosidase was determined in vitro and the kinetics of enzyme inhibition was studied. Dialysis experiment was performed to find the nature of the inhibition. Normal male Albino wistar rats and STZ induced diabetic rats were treated with cinnamon extract to find the effect of cinnamon on postprandial hyperglycemia after carbohydrate loading. Results Phytochemical analysis of the methanol extract displayed the presence of tannins, flavonoids, glycosides, terpenoids, coumarins and anthraquinones. In vitro studies had indicated dose-dependent inhibitory activity of cinnamon extract against yeast α-glucosidase with the IC 50 value of 5.83 μg/ml and mammalian α-glucosidase with IC 50 value of 670 μg/ml. Enzyme kinetics data fit to LB plot pointed out competitive mode of inhibition and the membrane dialysis experiment revealed reversible nature of inhibition. In vivo animal experiments are indicative of ameliorated postprandial hyperglycemia as the oral intake of the cinnamon extract (300 mg/kg body wt.) significantly dampened the postprandial hyperglycemia by 78.2% and 52.0% in maltose and sucrose

  8. Cinnamon extract inhibits α-glucosidase activity and dampens postprandial glucose excursion in diabetic rats

    Directory of Open Access Journals (Sweden)

    Thirumurugan Kavitha

    2011-06-01

    Full Text Available Abstract Background α-glucosidase inhibitors regulate postprandial hyperglycemia (PPHG by impeding the rate of carbohydrate digestion in the small intestine and thereby hampering the diet associated acute glucose excursion. PPHG is a major risk factor for diabetic vascular complications leading to disabilities and mortality in diabetics. Cinnamomum zeylanicum, a spice, has been used in traditional medicine for treating diabetes. In this study we have evaluated the α-glucosidase inhibitory potential of cinnamon extract to control postprandial blood glucose level in maltose, sucrose loaded STZ induced diabetic rats. Methods The methanol extract of cinnamon bark was prepared by Soxhlet extraction. Phytochemical analysis was performed to find the major class of compounds present in the extract. The inhibitory effect of cinnamon extract on yeast α-glucosidase and rat-intestinal α-glucosidase was determined in vitro and the kinetics of enzyme inhibition was studied. Dialysis experiment was performed to find the nature of the inhibition. Normal male Albino wistar rats and STZ induced diabetic rats were treated with cinnamon extract to find the effect of cinnamon on postprandial hyperglycemia after carbohydrate loading. Results Phytochemical analysis of the methanol extract displayed the presence of tannins, flavonoids, glycosides, terpenoids, coumarins and anthraquinones. In vitro studies had indicated dose-dependent inhibitory activity of cinnamon extract against yeast α-glucosidase with the IC 50 value of 5.83 μg/ml and mammalian α-glucosidase with IC 50 value of 670 μg/ml. Enzyme kinetics data fit to LB plot pointed out competitive mode of inhibition and the membrane dialysis experiment revealed reversible nature of inhibition. In vivo animal experiments are indicative of ameliorated postprandial hyperglycemia as the oral intake of the cinnamon extract (300 mg/kg body wt. significantly dampened the postprandial hyperglycemia by 78.2% and 52

  9. Borneo stalagmites reveal climatic excursions associated with Toba ash layers prior to Greenland Stadial 20

    Science.gov (United States)

    Cobb, K. M.; Orland, I. J.; Carolin, S.; Adkins, J. F.; Valley, J. W.; Jersild, A.; LeGrande, A. N.; Colose, C.

    2017-12-01

    The Toba super-eruption occurred in close association with an abrupt climate transition from Greenland Interstadial (GI-) 20 to Greenland Stadial (GS-) 20, roughly 74 thousand years ago. However, recent attempts to characterize either the regional or global climate response to Toba have been limited by a lack of age control, geographic proximity, and/or convincing marker of the major eruption in most high-resolution paleoclimate archives. Here, we use a suite of micro-scale analytical techniques to evaluate the oxygen isotopic and geochemical composition of multiple stalagmites that grew across the Toba interval in Gunung Mulu National Park, northern Borneo. New timeseries of stalagmite d18O at 50-micron scales across the Toba horizon revleal a large (>1‰), rapid (<200 yr) increase in d18O values within age-error of the 40Ar/39Ar age of the Youngest Toba Tuff (73.9±0.6 ky BP; Storey et al., 2012). We supplement these traditional mass spectrometric measurements with d18O timeseries made on 9-micron spots using the WiscSIMS CAMECA ims 1280 ion microprobe in time-transgressive segments across the Toba horizon in two well-dated stalagmites previously published in Carolin et al., 2013 and Caroline et al., 2014. The SIMS d18O data reveal high-frequency d18O excursions of +2 and -2 per mil during the transition from GI-20 (warm conditions) to Greenland Stadial GS-20 (cool conditions), suggesting that this period was characterized by large fluctuations in regional hydroclimate in the western tropical Pacific, with potentially profound impacts on global atmospheric circulation. We also present results from synchrotron analyses of ash-related elements (S, P, Si, and Al) to resolve the number and relative magnitude of Toba-related eruptions as recorded in several different stalagmites from Borneo, where ash layers likely exceeded 2cm on the overlying terrain. Together, these results indicate that large, rapid ( 10yr-long) environmental changes with marked effects on both

  10. VENUS-2, Reactor Kinetics with Feedback, 2-D LMFBR Disassembly Excursions

    International Nuclear Information System (INIS)

    Jackson, J.F.; Nicholson, R.B.; Weber, D.P.

    1980-01-01

    1 - Description of problem or function: VENUS-2 is an improved edition of the VENUS fast-reactor disassembly program. It is a two- dimensional (r-z) coupled neutronics-hydrodynamics code that calculates the dynamic behavior of an LMFBR during a prompt-critical disassembly excursion. It calculates the power history and fission energy release as well as the space-time histories of the fuel temperatures, core material pressures, and core material motions. Reactivity feedback effects due to Doppler broadening and reactor material motion are taken into account. 2 - Method of solution: The power and energy release are calculated using a point-kinetics formulation with up to six delayed neutron groups. The reactivity is a combination of an input driving function and feedback effects due to Doppler broadening and material motion. An adiabatic model is used to calculate the temperature increase throughout the reactor based on an initial temperature distribution and power profile provided as input data. These temperatures are, in turn, converted to fuel pressures through one of several equation of state options provided. The material motion that results from the pressure buildup is calculated by a direct finite difference solution of a set of two-dimensional (r-z) hydrodynamics equations. This is done in Lagrangian coordinates. The reactivity change associated with this motion is calculated by first-order perturbation theory. The displacements are also used to adjust the fuel densities as required for the density dependent equation-of- state option. An automatic time-step-size selection scheme is provided. 3 - Restrictions on the complexity of the problem: VENUS-2 is written so that the dimensions of the storage arrays can be readily changed to accommodate a broad range of problem sizes. In the base version, the total number of mesh intervals is restricted such that (NR+3)*(NZ+3) is less than 700, where NR and NZ are the total number of mesh intervals in the r and z

  11. An introduction to finite projective planes

    CERN Document Server

    Albert, Abraham Adrian

    2015-01-01

    Geared toward both beginning and advanced undergraduate and graduate students, this self-contained treatment offers an elementary approach to finite projective planes. Following a review of the basics of projective geometry, the text examines finite planes, field planes, and coordinates in an arbitrary plane. Additional topics include central collineations and the little Desargues' property, the fundamental theorem, and examples of finite non-Desarguesian planes.Virtually no knowledge or sophistication on the part of the student is assumed, and every algebraic system that arises is defined and

  12. Systems considerations in mosaic focal planes

    Science.gov (United States)

    White, K. P., III

    1983-08-01

    Two key reasons for pursuing the development of mosaic focal planes are reviewed and it is shown that rapid frame repetition rate is the only requirement that can be solved no other way than through mosaic focal planes. With the view that spaceborne mosaic focal plane sensors are necessarily 'smart sensors' requiring a lot of onboard processing just to function, it is pointed out that various artificial intelligence techniques may be the most appropriate to incorporate in the data processing. Finally, a novel mosaic focal plane design is proposed, termed a virtual mosaic focal plane, in response to other system constraints.

  13. Systolic Strain Abnormalities to Predict Hospital Readmission in Patients With Heart Failure and Normal Ejection Fraction

    Science.gov (United States)

    Borer, Steven M.; Kokkirala, Aravind; O'Sullivan, David M.; Silverman, David I.

    2011-01-01

    Background Despite intensive investigation, the pathogenesis of heart failure with normal ejection fraction (HFNEF) remains unclear. We hypothesized that subtle abnormalities of systolic function might play a role, and that abnormal systolic strain and strain rate would provide a marker for adverse outcomes. Methods Patients of new CHF and left ventricular ejection fraction > 50% were included. Exclusion criteria were recent myocardial infarction, severe valvular heart disease, severe left ventricular hypertrophy (septum >1.8 cm), or a technically insufficient echocardiogram. Average peak systolic strain and strain rate were measured using an off-line grey scale imaging technique. Systolic strain and strain rate for readmitted patients were compared with those who remained readmission-free. Results One hundred consecutive patients with a 1st admission for HFNEF from January 1, 2004 through December 31, 2007, inclusive, were analyzed. Fifty two patients were readmitted with a primary diagnosis of heart failure. Systolic strain and strain rates were reduced in both study groups compared to controls. However, systolic strain did not differ significantly between the two groups (-11.7% for those readmitted compared with -12.9% for those free from readmission, P = 0.198) and systolic strain rates also were similar (-1.05 s-1 versus -1.09 s-1, P = 0.545). E/e’ was significantly higher in readmitted patients compared with those who remained free from readmission (14.5 versus 11.0, P = 0.013). E/e’ (OR 1.189, 95% CI 1.026-1.378; P = 0.021) was found to be an independent predictor for HFNEF readmission. Conclusions Among patients with new onset HFNEF, SS and SR rates are reduced compared with patients free of HFNEF, but do not predict hospital readmission. Elevated E/e’ is a predictor of readmission in these patients. PMID:28352395

  14. Influence of time restriction, 20 minutes and 94.6 months, of visual information on angular displacement during the sit-to-stand (STS) task in three planes.

    Science.gov (United States)

    Aylar, Mozhgan Faraji; Firouzi, Faramarz; Araghi, Mandana Rahnama

    2016-12-01

    [Purpose] The purpose of this investigation was to assess whether or not restriction of visual information influences the kinematics of sit-to-stand (STS) performance in children. [Subjects and Methods] Five girls with congenital blindness (CB) and ten healthy girls with no visual impairments were randomly selected. The girls with congenital blindness were placed in one group and the ten girls with no visual impairments were divided into two groups of five, control and treatment groups. The participants in the treatment group were asked to close their eyes (EC) for 20 minutes before the STS test, whereas those in the control group kept their eyes open (EO). The performance of the participants in all three groups was measured using a motion capture system and two force plates. [Results] The results show that the constraint duration of visual sensory information affected the range of motion (ROM), the excursion of the dominant side ankle, and the ROM of the dominant side knee in the EC group. However, only ankle excursion on the non-dominant side was affected in the CB group, and this was only observed in the sagittal plane. [Conclusion] These results indicate that visual memory does not affect the joint angles in the frontal and transverse planes. Moreover, all of the participants could perform the STS transition without falling, indicating; the participants performed the STS maneuver correctly in all planes except the sagittal one.

  15. Fractionation between inorganic and organic carbon during the Lomagundi (2.22 2.1 Ga) carbon isotope excursion

    Science.gov (United States)

    Bekker, A.; Holmden, C.; Beukes, N. J.; Kenig, F.; Eglinton, B.; Patterson, W. P.

    2008-07-01

    The Lomagundi (2.22-2.1 Ga) positive carbon isotope excursion in shallow-marine sedimentary carbonates has been associated with the rise in atmospheric oxygen, but subsequent studies have demonstrated that the carbon isotope excursion was preceded by the rise in atmospheric oxygen. The amount of oxygen released to the exosphere during the Lomagundi excursion is constrained by the average global fractionation between inorganic and organic carbon, which is poorly characterized. Because dissolved inorganic and organic carbon reservoirs were arguably larger in the Paleoproterozoic ocean, at a time of lower solar luminosity and lower ocean redox state, decoupling between these two variables might be expected. We determined carbon isotope values of carbonate and organic matter in carbonates and shales of the Silverton Formation, South Africa and in the correlative Sengoma Argillite Formation, near the border in Botswana. These units were deposited between 2.22 and 2.06 Ga along the margin of the Kaapvaal Craton in an open-marine deltaic setting and experienced lower greenschist facies metamorphism. The prodelta to offshore marine shales are overlain by a subtidal carbonate sequence. Carbonates exhibit elevated 13C values ranging from 8.3 to 11.2‰ vs. VPDB consistent with deposition during the Lomagundi positive excursion. The total organic carbon (TOC) contents range from 0.01 to 0.6% and δ13C values range from - 24.8 to - 13.9‰. Thus, the isotopic fractionation between organic and carbonate carbon was on average 30.3 ± 2.8‰ ( n = 32) in the shallow-marine environment. The underlying Sengoma shales have highly variable TOC contents (0.14 to 21.94%) and δ13C values (- 33.7 to - 20.8‰) with an average of - 27.0 ± 3.0‰ ( n = 50). Considering that the shales were also deposited during the Lomagundi excursion, and taking δ13C values of the overlying carbonates as representative of the δ13C value of dissolved inorganic carbon during shale deposition, a carbon

  16. Effect of atrial systole on canine and porcine coronary blood flow.

    Science.gov (United States)

    Bellamy, R F

    1981-09-01

    A feature of phasic coronary flow patterns recorded in conscious chronically instrumented dogs is the atrial cove--a transient depression of arterial flow that occurs during atrial systole. The association between the hemodynamic effects of atrial systole and the atrial cove was studied in anesthetized dogs and pigs with complete heart block. Many atrial coves are available for study in these preparations because atrial activity continues unabated during the diastolic ventricular arrest that follows cessation of electrical pacing. The effect of atrial systole is to translate the pressure-flow relation found during diastole to a higher intercept pressure without change in slope. The increase in the intercept pressure equals the increase in intramyocardial pressure measured with microtransducers embedded in the left ventricular wall. The decrement in flow during the atrial cove is a direct function of the change in intramyocardial pressure and an inverse function of coronary vascular resistance. Each atrial systole is associated with a forward flow transient in the coronary veins, the peak of which occurs at the same instant as does the nadir of atrial flow. These data suggest that the coronary vessels are acting as collapsible tubes and that the waterfall model of the coronary circulation is applicable. The following sequence is proposed to account for the atrial cove. Atrial systole ejects a bolus of blood into the left ventricle increasing both ventricular cavity and intramyocardial pressures. The increase in intramyocardial pressure raises the back pressure opposing coronary flow, reducing the arterial perfusion pressure gradient and causing flow to fall.

  17. Second measurement of morning systolic blood pressure is more closely associated with albuminuria.

    Science.gov (United States)

    Sakabe, Kazumi; Fukui, Michiaki; Ushigome, Emi; Hamaguchi, Masahide; Tanaka, Toru; Atsuta, Haruhiko; Ohnishi, Masayoshi; Oda, Yohei; Hasegawa, Goji; Nakamura, Naoto

    2012-08-01

    It is important to control blood pressure as well as to control blood glucose for the prevention of diabetic nephropathy. However, to our knowledge, there are no reports investigating which blood pressure, including morning, evening and clinic, is more closely associated with albuminuria and whether one measurement is sufficient or not in patients with Type 2 diabetes. We measured morning, evening and clinic blood pressure and compared the area under the curve (AUC) of blood pressure for urinary albumin excretion equal to or more than 30 mg/g creatinine using receiver-operating characteristic curve analyses and odds ratio for albuminuria defined as urinary albumin excretion equal to or more than 30 mg/g creatinine in 858 patients with Type 2 diabetes. Odds ratio (95% confidence interval (CI)) of morning, evening and clinic systolic blood pressure for albuminuria was 1.034 (1.024 - 1.044), 1.033 (1.023 - 1.043) and 1.013 (1.055 - 1.021), respectively (p AUC of morning, evening and clinic systolic blood pressure was 0.644 (0.628 - 0.700) (p AUC of the second morning systolic blood pressure was greater than the first (p = 0.033). The second measurement of morning systolic blood pressure is more closely associated with albuminuria than the first measurement of the morning in addition to clinic systolic blood pressure.

  18. Systolic blood pressure is superior to other haemodynamic predictors of outcome in community acquired pneumonia.

    Science.gov (United States)

    Chalmers, J D; Singanayagam, A; Hill, A T

    2008-08-01

    Admission blood pressure (BP) assessment is a central component of severity assessment for community acquired pneumonia. The aim of this study was to establish which readily available haemodynamic measure on admission is most useful for predicting severity in patients admitted with community acquired pneumonia. A prospective observational study of patients admitted with community acquired pneumonia was conducted in Edinburgh, UK. The measurements compared were systolic and diastolic BP, mean arterial pressure and pulse pressure. The outcomes of interest were 30 day mortality and the requirement for mechanical ventilation and/or inotropic support. Admission systolic BP pressure pressure AUC values for each predictor of 30 day mortality were as follows: systolic BP pressure pressure AUC values for each predictor of need for mechanical ventilation and/or inotropic support were as follows: systolic BP pressure pressure blood pressure AUC 0.76 vs 0.74) and to the standard CURB65 score (0.76 vs 0.76) for the prediction of 30 day mortality. The simplified CRB65 score was equivalent for prediction of mechanical ventilation and/or inotropic support to standard CRB65 (0.77 vs 0.77) and to CURB65 (0.77 vs 0.78). Systolic BP is superior to other haemodynamic predictors of 30 day mortality and need for mechanical ventilation and/or inotropic support in community acquired pneumonia. The CURB65 score can be simplified to a modified CRB65 score by omission of the diastolic BP criterion without compromising its accuracy.

  19. Impact of age on pulmonary artery systolic pressures at rest and with exercise

    Directory of Open Access Journals (Sweden)

    Garvan C Kane

    2016-06-01

    Full Text Available Aim: It is not well known if advancing age influences normal rest or exercise pulmonary artery pressures. The purpose of the study was to evaluate the association of increasing age with measurements of pulmonary artery systolic pressure at rest and with exercise. Subjects and methods: A total of 467 adults without cardiopulmonary disease and normal exercise capacity (age range: 18–85 years underwent symptom-limited treadmill exercise testing with Doppler measurement of rest and exercise pulmonary artery systolic pressure. Results: There was a progressive increase in rest and exercise pulmonary artery pressures with increasing age. Pulmonary artery systolic pressures at rest and with exercise were 25 ± 5 mmHg and 33 ± 9 mmHg, respectively, in those <40 years, and 30 ± 5 mmHg and 41 ± 12 mmHg, respectively, in those ≥70 years. While elevated left-sided cardiac filling pressures were excluded by protocol design, markers of arterial stiffness associated with the age-dependent effects on pulmonary pressures. Conclusion: These data demonstrate that in echocardiographically normal adults, pulmonary artery systolic pressure increases with advancing age. This increase is seen at rest and with exercise. These increases in pulmonary pressure occur in association with decreasing transpulmonary flow and increases in systemic pulse pressure, suggesting that age-associated blood vessel stiffening may contribute to these differences in pulmonary artery systolic pressure.

  20. Systolic function evaluated with cardiovascular magnetic resonance imaging in HIV-infected patients

    Directory of Open Access Journals (Sweden)

    Leonie Scholtz

    2016-11-01

    Objectives: To ascertain whether there were any morphological abnormalities or systolic functional impairments on CMR in untreated asymptomatic HIV-infected patients, compared with HIV-uninfected control individuals. Methods: The CMR studies were performed using a 1.5-T whole-body clinical magnetic resonance 16-channel scanner (Achieva, Philips Medical Systems, Best, The Netherlands, using a cardiac five-element phased-array receiver coil (SENSE coil. Functional assessment was performed on 36 HIV-infected patients and the findings compared with 35 HIV-uninfected control patients who were matched for age and sex. Results: There was no significant difference in systolic function between the HIV-uninfected and the HIV-infected patients. The left ventricular end diastolic mass (LVEDM was slightly higher in the HIV-infected group, but this was statistically insignificant. Conclusion: No significant differences were found regarding the CMR systolic functional analysis and morphological parameters between the HIV-infected and the healthy volunteers.

  1. Prognostic value of systolic mitral annular velocity measured with Doppler tissue imaging in patients with chronic heart failure caused by left ventricular systolic dysfunction

    Science.gov (United States)

    Nikitin, N P; Loh, P H; de Silva, R; Ghosh, J; Khaleva, O Y; Goode, K; Rigby, A S; Alamgir, F; Clark, A L; Cleland, J G F

    2006-01-01

    Objective To assess the prognostic value of various conventional and novel echocardiographic indices in patients with chronic heart failure (CHF) caused by left ventricular (LV) systolic dysfunction. Methods 185 patients with a mean (SD) age of 67 (11) years with CHF and LV ejection fraction < 45% despite optimal pharmacological treatment were prospectively enrolled. The patients underwent two dimensional echocardiography with tissue harmonic imaging to assess global LV systolic function and obtain volumetric data. Transmitral flow was assessed with conventional pulse wave Doppler. Systolic (Sm), early, and late diastolic mitral annular velocities were measured with the use of colour coded Doppler tissue imaging. Results During a median follow up of 32 months (range 24–38 months in survivors), 34 patients died and one underwent heart transplantation. Sm velocity (hazard ratio (HR) 0.648, 95% confidence interval (CI) 0.463 to 0.907, p  =  0.011), diastolic arterial pressure (HR 0.965, 95% CI 0.938 to 0.993, p  =  0.015), serum creatinine (HR 1.006, 95% CI 1.001 to 1.011, p  =  0.023), LV ejection fraction (HR 0.945, 95% CI 0.899 to 0.992, p  =  0.024), age (HR 1.035, 95% CI 1.000 to 1.071, p  =  0.052), LV end systolic volume index (HR 1.009, 95% CI 0.999 to 1.019, p  =  0.067), and restrictive pattern of transmitral flow (HR 0.543, 95% CI 0.278 to 1.061, p  =  0.074) predicted the outcome of death or transplantation on univariate analysis. On multivariate analysis, only Sm velocity (HR 0.648, 95% CI 0.460 to 0.912, p  =  0.013) and diastolic arterial pressure (HR 0.966, 95% CI 0.938 to 0.994, p  =  0.016) emerged as independent predictors of outcome. Conclusions In patients with CHF and LV systolic dysfunction despite optimal pharmacological treatment, the strongest independent echocardiographic predictor of prognosis was Sm velocity measured with quantitative colour coded Doppler tissue

  2. A Collaborative Knowledge Plane for Autonomic Networks

    Science.gov (United States)

    Mbaye, Maïssa; Krief, Francine

    Autonomic networking aims to give network components self-managing capabilities. Several autonomic architectures have been proposed. Each of these architectures includes sort of a knowledge plane which is very important to mimic an autonomic behavior. Knowledge plane has a central role for self-functions by providing suitable knowledge to equipment and needs to learn new strategies for more accuracy.However, defining knowledge plane's architecture is still a challenge for researchers. Specially, defining the way cognitive supports interact each other in knowledge plane and implementing them. Decision making process depends on these interactions between reasoning and learning parts of knowledge plane. In this paper we propose a knowledge plane's architecture based on machine learning (inductive logic programming) paradigm and situated view to deal with distributed environment. This architecture is focused on two self-functions that include all other self-functions: self-adaptation and self-organization. Study cases are given and implemented.

  3. A comparison of systolic time intervals measured by impedance cardiography and carotid pulse tracing

    DEFF Research Database (Denmark)

    Mehlsen, J; Bonde, J; Rehling, Michael

    1990-01-01

    The purpose of this study was to compare the systolic time intervals (STI) obtained by impedance cardiography and by the conventional carotid technique. This comparison was done with respect to: 1) correlations between variables obtained by the two methods, 2) ability to reflect drug-induced chan......The purpose of this study was to compare the systolic time intervals (STI) obtained by impedance cardiography and by the conventional carotid technique. This comparison was done with respect to: 1) correlations between variables obtained by the two methods, 2) ability to reflect drug...

  4. The impact of animation on the length of stay and radius of movement of the excursion-recreational tourism

    Directory of Open Access Journals (Sweden)

    Dimitrić Dragana

    2016-01-01

    Full Text Available The basic hypothesis from which we started in the paper is the claim that animation of visitors has a direct impact on the length and radius of excursion-recreational tourism. The main objective of the research is to define the role of animation in the choice of tourist destination and length of staying. In the area of the City of Belgrade, there are more protected natural areas and one of them is the Great War Island located at the confluence of the River Sava in River Danube. This area has three protected zones. Temporary population that was the subject of the interview, as well as the Association of Tourist Guides of Serbia occupate one of these zones. We concluded that one of the biggest advantages of developing tourism of the Great War Island is the possibility of developing certain forms of tourism, and one of these forms, the excursion-recreational tourism has multiple positive effects on the population. The paper concluded that the animation proportionally affects the length of stay of tourists, as well as the radius of their movement.

  5. Accidental nuclear excursion Recuplex operation 234-5 facility. Final report: Date of incident: April 7, 1962

    Energy Technology Data Exchange (ETDEWEB)

    1962-08-01

    On Saturday morning, April 7, 1962, at about 1059 Armed Forces time, an accidental nuclear excursion occurred in the plutonium waste recovery facility (Recuplex) of the 234-5 Building. This excursion did not result in any mechanical damage or spread of contamination. Three employees of the General Electric Company received overexposures to gamma and neutron radiation. None were fatally exposed; in each case the overexposure was recognized promptly, and following medical observation and testing the men were released to return to work. In compliance with AEC Manual Chapter 0703, an AEC-HAPO committee composed of two AEC employees and five General Electric employees was appointed by the Manger, HOO, with the concurrence of the General Manager, HAPO, to conduct an investigation of the incident. The committee`s purpose was to determine the cause, nature, and extent of the incident, and recommend action to be taken by others to minimize or preclude future incidents of this magnitude. A study of operating practices and operating conditions that appeared to exist prior to, during, and subsequent to the accident was made by the committee. The committee believes that this report provides sufficient information to answer questions which may arise as a result of the criticality incident except those relating to its cause.

  6. Radioactivity in the galactic plane

    Science.gov (United States)

    Walraven, G. D.; Haymes, R. C.

    1976-01-01

    The paper reports the detection of a large concentration of interstellar radioactivity during balloon-altitude measurements of gamma-ray energy spectra in the band between 0.02 and 12.27 MeV from galactic and extragalactic sources. Enhanced counting rates were observed in three directions towards the plane of the Galaxy; a power-law energy spectrum is computed for one of these directions (designated B 10). A large statistical deviation from the power law in a 1.0-FWHM interval centered near 1.16 MeV is discussed, and the existence of a nuclear gamma-ray line at 1.15 MeV in B 10 is postulated. It is suggested that Ca-44, which emits gamma radiation at 1.156 MeV following the decay of radioactive Sc-44, is a likely candidate for this line, noting that Sc-44 arises from Ti-44 according to explosive models of supernova nucleosynthesis. The 1.16-MeV line flux inferred from the present data is shown to equal the predicted flux for a supernova at a distance of approximately 3 kpc and an age not exceeding about 100 years.

  7. Compact planes, mostly 8-dimensional. A retrospect

    OpenAIRE

    Salzmann, Helmut R.

    2014-01-01

    Results on $8$-dimensional topological planes are scattered in the literature. It is the aim of the present paper to give a survey of these geometries, in particular of information obtained after the appearance of the treatise Compact Projective Planes or not included in this book. For some theorems new proofs are given and a few related results concerning planes of other dimensions are presented.

  8. Highway driving safety the day after using sleep medication: the direction of lapses and excursions out-of-lane in drowsy drivers.

    Science.gov (United States)

    Verster, Joris C; Mooren, Loes; Bervoets, Adriana C; Roth, Thomas

    2017-10-24

    The primary outcome measure of the on-road driving test is the Standard Deviation of Lateral Position. However, other outcome measures, such as lapses and excursions out-of-lane, also need to be considered as they may be related to crash risk. The aim of this study was to determine the direction of lapses and excursions out-of-lane (i.e. towards/into the adjacent traffic lane or towards/into the road shoulder). In total, data from 240 driving tests were re-analysed, and 628 lapses and 401 excursions out-of-lane were identified. The analyses revealed that lapses were made equally frequently over left (49.4%) and over right (43.3%). In contrast, excursions out-of-lane were almost exclusively directed over right into the (safer) road shoulder (97.3%). These findings suggest that drivers are unaware of having lapses, whereas excursions out-of-lane are events where the driver is aware of loss of vehicle control. © 2017 The Authors. Journal of Sleep Research published by John Wiley & Sons Ltd on behalf of European Sleep Research Society.

  9. Nanostructured carbon films with oriented graphitic planes

    International Nuclear Information System (INIS)

    Teo, E. H. T.; Kalish, R.; Kulik, J.; Kauffmann, Y.; Lifshitz, Y.

    2011-01-01

    Nanostructured carbon films with oriented graphitic planes can be deposited by applying energetic carbon bombardment. The present work shows the possibility of structuring graphitic planes perpendicular to the substrate in following two distinct ways: (i) applying sufficiently large carbon energies for deposition at room temperature (E>10 keV), (ii) utilizing much lower energies for deposition at elevated substrate temperatures (T>200 deg. C). High resolution transmission electron microscopy is used to probe the graphitic planes. The alignment achieved at elevated temperatures does not depend on the deposition angle. The data provides insight into the mechanisms leading to the growth of oriented graphitic planes under different conditions.

  10. Lower incisor inclination regarding different reference planes.

    Science.gov (United States)

    Zataráin, Brenda; Avila, Josué; Moyaho, Angeles; Carrasco, Rosendo; Velasco, Carmen

    2016-09-01

    The purpose of this study was to assess the degree of lower incisor inclination with respect to different reference planes. It was an observational, analytical, longitudinal, prospective study conducted on 100 lateral cephalograms which were corrected according to the photograph in natural head position in order to draw the true vertical plane (TVP). The incisor mandibular plane angle (IMPA) was compensated to eliminate the variation of the mandibular plane growth type with the formula "FMApx.- 25 (FMA) + IMPApx. = compensated IMPA (IMPACOM)". As the data followed normal distribution determined by the KolmogorovSmirnov test, parametric tests were used for the statistical analysis, Ttest, ANOVA and Pearson coefficient correlation test. Statistical analysis was performed using a statistical significance of p planes. There were statistically significant differences among the means of the planes measured, except for IMPACOM, FMIA and TVP. The IMPA differed significantly from the IMPACOM. The compensated IMPA and the FMIA did not differ significantly from the TVP. The true horizontal plane was mismatched with Frankfort plane in 84% of the sample with a range of 19°. The true vertical plane is adequate for measuring lower incisor inclination. Sociedad Argentina de Investigación Odontológica.

  11. Flux dynamics in ultrasensitive superconducting focal planes

    Data.gov (United States)

    National Aeronautics and Space Administration — The performance of superconducting focal planes will drive the achievable specifications of ultrasensitive instruments for NASA astrophysics missions, yet they have...

  12. Additional diagnostic value of systolic dysfunction induced by dipyridamole stress cardiac magnetic resonance used in detecting coronary artery disease.

    Science.gov (United States)

    Husser, Oliver; Bodí, Vicente; Sanchís, Juan; Mainar, Luis; Núñez, Julio; López-Lereu, María P; Monmeneu, José V; Ruiz, Vicente; Rumiz, Eva; Moratal, David; Chorro, Francisco J; Llácer, Angel

    2009-04-01

    Dipyridamole stress perfusion cardiovascular magnetic resonance (CMR) is used to detect coronary artery disease (CAD). However, few data are available on the diagnostic value of the systolic dysfunction induced by dipyridamole. This study investigated whether the induction of systolic dysfunction supplements the diagnostic information provided by perfusion imaging in the detection of CAD. Overall, 166 patients underwent dipyridamole CMR and quantitative coronary angiography, with CAD being defined as a stenosis > or =70%. Systolic dysfunction at rest, systolic dysfunction with dipyridamole, induced systolic dysfunction, and stress first-pass perfussion deficit (PD) and delayed enhancement were quantified. In the multivariate analysis, PD (hazard ratio [HR]=1.6; 95% confidence interval [CI], 1.33-1.91;Pstatistic for predicting CAD (0.81 vs. 0.87; P=.02). Combining induced systolic dysfunction with perfusion imaging increases the diagnostic accuracy of detecting CAD and enables patients with severe ischemia and a high probability of CAD to be identified.

  13. Colliding almost-plane gravitational waves: Colliding plane waves and general properties of almost-plane-wave spacetimes

    International Nuclear Information System (INIS)

    Yurtsever, U.

    1988-01-01

    It is well known that when two precisely plane-symmetric gravitational waves propagating in an otherwise flat background collide, they focus each other so strongly as to produce a curvature singularity. This paper is the first of several devoted to almost-plane gravitational waves and their collisions. Such waves are more realistic than plane waves in having a finite but very large transverse size. In this paper we review some crucial features of the well-known exact solutions for colliding plane waves and we argue that one of these features, the breakdown of ''local inextendibility'' can be regarded as nongeneric. We then introduce a new framework for analyzing general colliding plane-wave spacetimes; we give an alternative proof of a theorem due to Tipler implying the existence of singularities in all generic colliding plane-wave solutions; and we discuss the fact that the recently constructed Chandrasekhar-Xanthopoulos colliding plane-wave solutions are not strictly plane symmetric and thus do not satisfy the conditions and the conclusion of Tipler's theorem

  14. Systolic left ventricular function according to left ventricular concentricity and dilatation in hypertensive patients

    DEFF Research Database (Denmark)

    Bang, Casper; Gerdts, Eva; Aurigemma, Gerard P

    2013-01-01

    Left ventricular hypertrophy [LVH, high left ventricular mass (LVM)] is traditionally classified as concentric or eccentric based on left ventricular relative wall thickness. We evaluated left ventricular systolic function in a new four-group LVH classification based on left ventricular dilatation...... [high left ventricular end-diastolic volume (EDV) index and concentricity (LVM/EDV)] in hypertensive patients....

  15. Decreasing systolic blood pressure and declining mortality rates in an untreated population

    DEFF Research Database (Denmark)

    Andersen, Ulla O; Marott, Jacob L; Jensen, Gorm B

    2011-01-01

    The aim of the present study was to evaluate developments in 30 years mortality risk that may be associated with developments in population systolic blood pressure (SBP) and to evaluate possible secular trends in BP-associated mortality risk in the untreated population....

  16. Systolic blood pressure reactivity during submaximal exercise and acute psychological stress in youth

    Science.gov (United States)

    Background: Studies in youth show an association between systolic blood-pressure (SBP) reactivity to acute psychological stress and carotid artery intima-media thickness (CIMT). However, it has not yet been determined whether SBP reactivity during submaximal exercise is also associated with CIMT i...

  17. Effect of preload alternations on a new Doppler echocardiographic index of combined systolic and diastolic performance

    DEFF Research Database (Denmark)

    Møller, J E; Poulsen, S H; Egstrup, K

    1999-01-01

    The objective of the study was to assess the effect of preload alternations on a nongeometric Doppler index of combined systolic and diastolic myocardial performance (MPI). Doppler echocardiography was performed during Valsalva maneuver, passive leg lifting, and after sublingual administration of...

  18. Dairy consumption, systolic blood pressure, and risk of hypertension: Mendelian randomization study

    Science.gov (United States)

    This study examined whether previous observed inverse associations of dairy intake with systolic blood pressure and risk of hypertension were causal. A Mendelian randomization study was employed, using the single nucleotide polymorphism rs4988235 related to lactase persistence as an instrumental var...

  19. Automatic selection of optimal systolic and diastolic reconstruction windows for dual-source CT coronary angiography

    International Nuclear Information System (INIS)

    Seifarth, H.; Puesken, M.; Wienbeck, S.; Maintz, D.; Heindel, W.; Juergens, K.U.; Fischbach, R.

    2009-01-01

    The aim of this study was to assess the performance of a motion-map algorithm that automatically determines optimal reconstruction windows for dual-source coronary CT angiography. In datasets from 50 consecutive patients, optimal systolic and diastolic reconstruction windows were determined using the motion-map algorithm. For manual determination of the optimal reconstruction window, datasets were reconstructed in 5% steps throughout the RR interval. Motion artifacts were rated for each major coronary vessel using a five-point scale. Mean motion scores using the motion-map algorithm were 2.4 ± 0.8 for systolic reconstructions and 1.9 ± 0.8 for diastolic reconstructions. Using the manual approach, overall motion scores were significantly better (1.9 ± 0.5 and 1.7 ± 0.6, p 90% of cases using either approach. Using the automated approach, there was a negative correlation between heart rate and motion scores for systolic reconstructions (ρ = -0.26, p 80 bpm (systolic reconstruction). (orig.)

  20. Microalbuminuria in patients with non-insulin-dependent diabetes mellitus relates to nocturnal systolic blood pressure.

    LENUS (Irish Health Repository)

    Mitchell, T H

    2012-02-03

    PURPOSE: Microalbuminuria predicts early mortality in non-insulin-dependent-diabetes mellitus patients (NIDDM). Our objective in the present study was to compare and assess the relationship between 24-hour, day and nocturnal ambulatory blood pressure (BP) and urinary albumin excretion rate (UAE) in microalbuminuric and normoalbuminuric NIDDM and in normal control subjects. PATIENTS AND METHODS: In the present cross-sectional study, 24 hour ambulatory BP (daytime BP and nocturnal BP) and HbA1c were compared in microalbuminuric (n = 10) and nonmicroalbuminuric NIDDM patients (n = 10) and in nondiabetic controls (n = 9). None of the patients were taking antihypertensive agents. RESULTS: In the microlbuminuric group, whereas 24 hour and daytime systolic BP differed significantly from control values (P < 0.025 and P < 0.05 respectively), there was no difference between diabetic groups. However, nocturnal systolic BP in the microalbuminuric group was significantly higher than in the normoalbuminuric diabetic patients (139 vs. 125) (P < 0.05) and a significant difference was also found between the NIDDM patients and the control group (139, 125 vs. 114) (P < 0.025). In multiple regression analysis, only nocturnal systolic BP showed a significant relationship with UAE (P < 0.05). CONCLUSIONS: We suggest that the higher nocturnal systolic blood pressure seen in our microalbuminuric NIDDM patients may contribute to the increased morbidity in this group.

  1. Exercise reveals impairments in left ventricular systolic function in patients with metabolic syndrome.

    Science.gov (United States)

    Fournier, Sara B; Reger, Brian L; Donley, David A; Bonner, Daniel E; Warden, Bradford E; Gharib, Wissam; Failinger, Conard F; Olfert, Melissa D; Frisbee, Jefferson C; Olfert, I Mark; Chantler, Paul D

    2014-01-01

    Metabolic syndrome (MetS) is the manifestation of a cluster of cardiovascular risk factors and is associated with a threefold increase in the risk of cardiovascular morbidity and mortality, which is suggested to be mediated, in part, by resting left ventricular (LV) systolic dysfunction. However, to what extent resting LV systolic function is impaired in MetS is controversial, and there are no data indicating whether LV systolic function is impaired during exercise. Accordingly, the objective of this study was to examine comprehensively the LV and arterial responses to exercise in individuals with MetS without diabetes and/or overt cardiovascular disease in comparison to a healthy control population. Cardiovascular function was characterized using Doppler echocardiography and gas exchange in individuals with MetS (n = 27) versus healthy control subjects (n = 20) at rest and during peak exercise. At rest, individuals with MetS displayed normal LV systolic function but reduced LV diastolic function compared with healthy control subjects. During peak exercise, individuals with MetS had impaired contractility, pump performance and vasodilator reserve capacity versus control subjects. A blunted contractile reserve response resulted in diminished arterial-ventricular coupling reserve and limited aerobic capacity in individuals with MetS versus control subjects. These findings are of clinical importance, because they provide insight into the pathophysiological changes in MetS that may predispose this population of individuals to an increased risk of cardiovascular morbidity and mortality.

  2. Systolically gated 3D phase contrast MRA of mesenteric arteries in suspected mesenteric ischemia

    Energy Technology Data Exchange (ETDEWEB)

    Wasser, M.N.; Schultze Kool, L.J.; Roos, A. de [Leiden Univ. Hospital (Netherlands)] [and others

    1996-03-01

    Our goal was to assess the value of MRA for detecting stenoses in the celiac (CA) and superior mesenteric (SMA) arteries in patients suspected of having chronic mesenteric ischemia, using an optimized systolically gated 3D phase contrast technique. In an initial study in 24 patients who underwent conventional angiography of the abdominal vessels for different clinical indications, a 3D phase contrast MRA technique (3D-PCA) was evaluated and optimized to image the CAs and SMAs. Subsequently, a prospective study was performed to assess the value of systolically gated 3D-PCA in evaluation of the mesenteric arteries in 10 patients with signs and symptoms of chronic mesenteric ischemia. Intraarterial digital subtraction angiography and surgical findings were used as the reference standard. In the initial study, systolic gating appeared to be essential in imaging the SMA on 3D-PCA. In 10 patients suspected of mesenteric ischemia, systolically gated 3D-PCA identified significant proximal disease in the two mesenteric vessels in 4 patients. These patients underwent successful reconstruction of their stenotic vessels. Cardiac-gated MRA may become a useful tool in selection of patients suspected of having mesenteric ischemia who may benefit from surgery. 16 refs., 6 figs., 4 tabs.

  3. Decreased mitochondrial oxidative phosphorylation capacity in the human heart with left ventricular systolic dysfunction

    DEFF Research Database (Denmark)

    Stride, Nis; Larsen, Steen; Hey-Mogensen, Martin

    2013-01-01

    Heart failure (HF) with left ventricular systolic dysfunction (LVSD) is associated with a shift in substrate utilization and a compromised energetic state. Whether these changes are connected with mitochondrial dysfunction is not known. We hypothesized that the cardiac phenotype in LVSD could...

  4. Systolic blood pressure estimation using PPG and ECG during physical exercise

    NARCIS (Netherlands)

    Sun, S.; Bezemer, R.; Long, X.; Muehlsteff, J.; Aarts, R.M.

    2016-01-01

    In this work, a model to estimate systolic blood pressure (SBP) using photoplethysmography (PPG) and electrocardiography (ECG) is proposed. Data from 19 subjects doing a 40 min exercise was analyzed. Reference SBP was measured at the finger based on the volume-clamp principle. PPG signals were

  5. Incidence and predictors of end-stage renal disease in outpatients with systolic heart failure

    DEFF Research Database (Denmark)

    Bosselmann, Helle; Gislason, Gunnar; Gustafsson, Finn

    2013-01-01

    Background- Renal dysfunction is an important prognostic factor in heart failure (HF), but whether this dysfunction progresses to end-stage renal disease (ESRD) is unknown. Therefore, we examined incidence and predictors of ESRD in outpatients with HF. Methods and Results- Patients with systolic ...

  6. Ratio of Systolic Blood Pressure to Right Atrial Pressure, a Novel Marker to Predict Morbidity and Mortality in Acute Systolic Heart Failure.

    Science.gov (United States)

    Omar, Hesham R; Charnigo, Richard; Guglin, Maya

    2017-04-01

    Congestion is the main contributor to heart failure (HF) morbidity and mortality. We assessed the combined role of congestion and decreased forward flow in predicting morbidity and mortality in acute systolic HF. The Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness trial data set was used to determine if the ratio of simultaneously measured systolic blood pressure (SBP)/right atrial pressure (RAP) on admission predicted HF rehospitalization and 6-month mortality. One hundred ninety-five patients (mean age 56.5 years, 75% men) who received pulmonary artery catheterization were studied. The RAP, SBP, and SBP/RAP had an area under the curve (AUC) of 0.593 (p = 0.0205), 0.585 (p = 0.0359), and 0.621 (p = 0.0026), respectively, in predicting HF rehospitalization. The SBP/RAP was a superior marker of HF rehospitalization compared with RAP alone (difference in AUC 0.0289, p = 0.0385). The optimal criterion of SBP/RAP AUC 0.622, p = 0.0108, and a cut-off value of SBP/RAP <8 had a sensitivity of 61.9% and specificity 64.1% in predicting mortality. Multivariate analysis showed that an SBP/RAP <11 independently predicted rehospitalization for HF (estimated odds ratio 3.318, 95% confidence interval 1.692 to 6.506, p = 0.0005) and an SBP/RAP <8 independently predicted mortality (estimated hazard ratio 2.025, 95% confidence interval 1.069 to 3.833, p = 0.030). In conclusion, SBP/RAP ratio is a marker that identifies a spectrum of complications after hospitalization of patients with decompensated systolic HF, starting with increased incidence of HF rehospitalization at SBP/RAP <11 to increased mortality with SBP/RAP <8. Copyright © 2017 Elsevier Inc. All rights reserved.

  7. Duration of and decoupling between carbon isotope excursions during the end-Triassic mass extinction and Central Atlantic Magmatic Province emplacement

    Science.gov (United States)

    Yager, Joyce A.; West, A. Joshua; Corsetti, Frank A.; Berelson, William M.; Rollins, Nick E.; Rosas, Silvia; Bottjer, David J.

    2017-09-01

    Changes in δ13Ccarb and δ13Corg from marine strata occur globally in association with the end-Triassic mass extinction and the emplacement of the Central Atlantic Magmatic Province (CAMP) during the break up of Pangea. As is typical in deep time, the timing and duration of these isotopic excursions has remained elusive, hampering attempts to link carbon cycle perturbations to specific processes. Here, we report δ13Ccarb and δ13Corg from Late Triassic and Early Jurassic strata near Levanto, Peru, where intercalated dated ash beds permit temporal calibration of the carbon isotope record. Both δ13Ccarb and δ13Corg exhibit a broad positive excursion through the latest Triassic into the earliest Jurassic. The first order positive excursion in δ13Corg is interrupted by a negative shift noted in many sections around the world coincident with the extinction horizon. Our data indicate that the negative excursion lasts 85 ± 25 kyrs, longer than inferred by previous studies based on cyclostratigraphy. A 260 ± 80 kyr positive δ13Corg shift follows, during which the first Jurassic ammonites appear. The overall excursion culminates in a return to pre-perturbation carbon isotopic values over the next 1090 ± 70 kyrs. Via chronologic, isotopic, and biostratigraphic correlation to other successions, we find that δ13Ccarb and δ13Corg return to pre-perturbation values as CAMP volcanism ceases and in association with the recovery of pelagic and benthic biota. However, the initiation of the carbon isotope excursion at Levanto predates the well-dated CAMP sills from North America, indicating that CAMP may have started earlier than thought based on these exposures, or that the onset of carbon cycle perturbations was not related to CAMP.

  8. Relationship of medial gastrocnemius relative fascicle excursion and ankle joint power and work performance during gait in typically developing children: A cross-sectional study.

    Science.gov (United States)

    Martín Lorenzo, Teresa; Albi Rodríguez, Gustavo; Rocon, Eduardo; Martínez Caballero, Ignacio; Lerma Lara, Sergio

    2017-07-01

    Muscle fascicles lengthen in response to chronic passive stretch through in-series sarcomere addition in order to maintain an optimum sarcomere length. In turn, the muscles' force generating capacity, maximum excursion, and contraction velocity is enhanced. Thus, longer fascicles suggest a greater capacity to develop joint power and work. However, static fascicle length measurements may not be taking sarcomere length differences into account. Thus, we considered relative fascicle excursions through passive ankle dorsiflexion may better correlate with the capacity to generate joint power and work than fascicle length. Therefore, the aim of the present study was to determine if medial gastrocnemius relative fascicle excursions correlate with ankle joint power and work generation during gait in typically developing children. A sample of typically developing children (n = 10) were recruited for this study and data analysis was carried out on 20 legs. Medial gastrocnemius relative fascicle excursion from resting joint angle to maximum dorsiflexion was estimated from trigonometric relations of medial gastrocnemius pennation angle and thickness obtained from B-mode real-time ultrasonography. Furthermore, a three-dimensional motion capture system was used to obtain ankle joint work and power during the stance phase of gait. Significant correlations were found between relative fascicle excursion and peak power absorption (-) r(14) = -0.61, P = .012 accounting for 31% variability, positive work r(18) = 0.56, P = .021 accounting for 31% variability, and late stance positive work r(15) = 0.51, P = .037 accounting for 26% variability. The large unexplained variance may be attributed to mechanics of neighboring structures (e.g., soleus or Achilles tendon mechanics) and proximal joint kinetics which may also contribute to ankle joint power and work performance, and were not taken into account. Further studies are encouraged to provide greater insight

  9. Discretization of superintegrable systems on a plane

    Science.gov (United States)

    Kabát, Z.

    2012-02-01

    We construct difference analogues of so called Smorodinsky-Winternitz superintegrable systems in the Euclidean plane. Using methods of umbral calculus, we obtain difference equations for generalized isotropic harmonic oscillator on the uniform lattice, and also its solution in terms of power series. In the case of gauge-rotated Hamiltonian, the solution is a polynomial, well-defined in the whole plane.

  10. Slipping and Rolling on an Inclined Plane

    Science.gov (United States)

    Aghamohammadi, Cina; Aghamohammadi, Amir

    2011-01-01

    In the first part of the paper, using a direct calculation two-dimensional motion of a particle sliding on an inclined plane is investigated for general values of friction coefficient ([mu]). A parametric equation for the trajectory of the particle is also obtained. In the second part of the paper, the motion of a sphere on the inclined plane is…

  11. Moving vertices to make drawings plane

    NARCIS (Netherlands)

    Goaoc, X.; Kratochvil, J.; Okamoto, Y.; Shin, C.S.; Wolff, A.; Hong, S.K.; Nishizeki, T.; Quan, W.

    2008-01-01

    In John Tantalo’s on-line game Planarity the player is given a non-plane straight-line drawing of a planar graph. The aim is to make the drawing plane as quickly as possible by moving vertices. In this paper we investigate the related problem MinMovedVertices which asks for the minimum number of

  12. The Mono Lake geomagnetic excursion recorded in loess: Its application as time marker and implications for its geomagnetic nature

    Science.gov (United States)

    Hambach, U.; Hark, M.; Zeeden, C.; Reddersen, B.; Zöller, L.; Fuchs, M.

    2009-04-01

    One of the youngest and worldwide documented geomagnetic excursions in the Brunhes Chron is the Mono Lake excursion (MLE). It has been detected in marine and terrestrial sedimentary archives as well as in lavas. Recent age determinations and age estimates for the MLE centre around an age interval of approximately 31 - 34 ka. Likewise the Laschamp excursion the MLE goes along with a distinct peak in cosmogenic radionuclides in ice cores and sedimentary archives. It provides therefore an additional geomagnetic time marker for various geoarchives to synchronise different climate archives. Here we report on a detailed record of the MLE from a loess site at Krems, Lower Austria. The site is situated on the southern slope of the Wachtberg hill in the vicinity of the old city centre of Krems. The archive comprises Middle to Upper Würmian (Late Pleistocene) loess in which an Upper Palaeolithic (Early Gravettian) cultural layer is embedded. The most spectacular finds are a double infant burial found in 2005 and a single burial discovered in 2006 (Einwögerer et al., 2006). Generally, archaeological findings show an extraordinarily good preservation due to embedding in rapidly sedimented loess (Händel et al., 2008). The about 10 m thick loess pile consists of calcareous sandy, coarse silt which is rich in mica indicating local sources. It is well stratified with brownish horizons representing embryonic soils pointing to incipient pedogenesis. Some of the pedo-horizons show occasionally indications of minor erosion and bedding-parallel sediment transport, but no linear erosional features. Pale greyish horizons are the result of partial gleying under permafrost conditions. No strong pedogenesis including decalcification and clay formation is present. The cultural layer is still covered by more than 5 m of loess, and dated by radiocarbon to ~27 ka 14C BP (Einwögerer et al., 2006). Below this layer up to 2.5 m of loess resting on Lower Pleistocene fluvial gravels are

  13. Open Cluster Dynamics via Fundamental Plane

    Science.gov (United States)

    Lin, Chien-Cheng; Pang, Xiao-Ying

    2018-04-01

    Open clusters (OCs) are important objects for stellar dynamics studies. The short survival timescale of OCs makes them closely related to the formation of Galactic field stars. We motivate to investigate the dynamical evolution of OCs on the aspect of internal effect and the external influence. Firstly, we make use of the known OC catalog to obtain OCs masses, effective radii. Additionally, we estimate OCs kinematics properties by OC members cross-matched with radial velocity and metallicity from SDSSIV/APOGEE2. We then establish the fundamental plane of OCs based on the radial velocity dispersion, the effective radius, and average surface brightness. The deviation of the fundamental plane from the Virial Plane, so called the tilt, and the r.m.s. dispersion of OCs around the average plane are used to indicate the dynamical status of OCs. Parameters of the fitted plane will vary with cluster age and distance.

  14. Slipping and rolling on an inclined plane

    International Nuclear Information System (INIS)

    Aghamohammadi, Cina; Aghamohammadi, Amir

    2011-01-01

    In the first part of the paper, using a direct calculation two-dimensional motion of a particle sliding on an inclined plane is investigated for general values of friction coefficient (μ). A parametric equation for the trajectory of the particle is also obtained. In the second part of the paper, the motion of a sphere on the inclined plane is studied. It is shown that the evolution equation for the contact point of a sliding sphere is similar to that of a point particle sliding on an inclined plane whose friction coefficient is 7/2 μ. If μ > 2/7 tan θ, for any arbitrary initial velocity and angular velocity, the sphere will roll on the inclined plane after some finite time. In other cases, it will slip on the inclined plane. In the case of rolling, the centre of the sphere moves on a parabola. Finally the velocity and angular velocity of the sphere are exactly computed.

  15. Coherent field propagation between tilted planes.

    Science.gov (United States)

    Stock, Johannes; Worku, Norman Girma; Gross, Herbert

    2017-10-01

    Propagating electromagnetic light fields between nonparallel planes is of special importance, e.g., within the design of novel computer-generated holograms or the simulation of optical systems. In contrast to the extensively discussed evaluation between parallel planes, the diffraction-based propagation of light onto a tilted plane is more burdensome, since discrete fast Fourier transforms cannot be applied directly. In this work, we propose a quasi-fast algorithm (O(N 3  log N)) that deals with this problem. Based on a proper decomposition into three rotations, the vectorial field distribution is calculated on a tilted plane using the spectrum of plane waves. The algorithm works on equidistant grids, so neither nonuniform Fourier transforms nor an explicit complex interpolation is necessary. The proposed algorithm is discussed in detail and applied to several examples of practical interest.

  16. Reliability of the Star Excursion Balance Test and Two New Similar Protocols to Measure Trunk Postural Control.

    Science.gov (United States)

    López-Plaza, Diego; Juan-Recio, Casto; Barbado, David; Ruiz-Pérez, Iñaki; Vera-Garcia, Francisco J

    2018-05-18

    Although the Star Excursion Balance test (SEBT) has shown a good intrasession reliability, the intersession reliability of this test has not been deeply studied. Furthermore, there is an evident high influence of the lower limbs in the performance of the SEBT, so even if it has been used to measure core stability, it is possibly not the most suitable measurement. The aims of this study were to (1) to assess the absolute and relative between-session reliability of the SEBT and 2 novel variations of this test to assess trunk postural control while sitting, ie, the Star Excursion Sitting Test (SEST) and the Star Excursion Timing Test (SETT); and (2) to analyze the relationships between these 3 test scores. Correlational and reliability test-retest study. Controlled laboratory environment. Twenty-seven physically active men (age: 24.54 ± 3.05 years). Relative and absolute reliability of the SEBT, SEST, and SETT were calculated through the intraclass correlation coefficient (ICC) and standard error of measurement (SEM), respectively. A Pearson correlation analysis was carried out between the variables of the 3 tests. Maximum normalized reach distances were assessed for different SEBT and SEST directions. In addition, composite indexes were calculated for SEBT, SEST, and SETT. The SEBT (dominant leg: ICC = 0.87 [0.73-0.94], SEM = 2.12 [1.66-2.93]; nondominant leg: ICC = 0.74 [0.50-0.87], SEM = 3.23 [2.54-4.45]), SEST (ICC = 0.85 [0.68-0.92], SEM = 1.27 [1.03-1.80]), and SETT (ICC = 0.61 [0.30-0.80], SEM = 2.31 [1.82-3.17]) composite indexes showed moderate-to-high 1-month reliability. A learning effect was detected for some SEBT and SEST directions and for SEST and SETT composite indexes. No significant correlations were found between SEBT and its 2 variations (r ≤ .366; P > .05). A significant correlation was found between the SEST and SETT composite indexes (r = .520; P > .01). SEBT, SEST, and SETT are reliable field protocols to measure postural control. However

  17. Characteristic systolic waveform of left ventricular longitudinal strain rate in patients with hypertrophic cardiomyopathy.

    Science.gov (United States)

    Okada, Kazunori; Kaga, Sanae; Mikami, Taisei; Masauzi, Nobuo; Abe, Ayumu; Nakabachi, Masahiro; Yokoyama, Shinobu; Nishino, Hisao; Ichikawa, Ayako; Nishida, Mutsumi; Murai, Daisuke; Hayashi, Taichi; Shimizu, Chikara; Iwano, Hiroyuki; Yamada, Satoshi; Tsutsui, Hiroyuki

    2017-05-01

    We analyzed the waveform of systolic strain and strain-rate curves to find a characteristic left ventricular (LV) myocardial contraction pattern in patients with hypertrophic cardiomyopathy (HCM), and evaluated the utility of these parameters for the differentiation of HCM and LV hypertrophy secondary to hypertension (HT). From global strain and strain-rate curves in the longitudinal and circumferential directions, the time from mitral valve closure to the peak strains (T-LS and T-CS, respectively) and the peak systolic strain rates (T-LSSR and T-CSSR, respectively) were measured in 34 patients with HCM, 30 patients with HT, and 25 control subjects. The systolic strain-rate waveform was classified into 3 patterns ("V", "W", and "√" pattern). In the HCM group, T-LS was prolonged, but T-LSSR was shortened; consequently, T-LSSR/T-LS ratio was distinctly lower than in the HT and control groups. The "√" pattern of longitudinal strain-rate waveform was more frequently seen in the HCM group (74 %) than in the control (4 %) and HT (20 %) groups. Similar but less distinct results were obtained in the circumferential direction. To differentiate HCM from HT, the sensitivity and specificity of the T-LSSR/T-LS ratio patients with HCM, a reduced T-LSSR/T-LS ratio and a characteristic "√"-shaped waveform of LV systolic strain rate was seen, especially in the longitudinal direction. The timing and waveform analyses of systolic strain rate may be useful to distinguish between HCM and HT.

  18. Study the Z-Plane Strip Capacitance

    International Nuclear Information System (INIS)

    Parikh, H.; Swain, S.

    2005-01-01

    The BaBaR detector at the Stanford Linear Accelerator Center is currently undergoing an upgrade to improve its muon and neutral hadron detection system. The Resistive Plate Chambers (RPCs) that had been used till now have deteriorated in performance over the past few years and are being replaced by Limited Streamer Tube (LSTs). Each layer of the system consists of a set of up to 10 streamer tube modules which provide one coordinate (φ coordinate) and a single ''Z-plane'' which provides the Z coordinate of the hit. The large area Z-planes (up to 12m 2 ) are 1mm thick and contain 96 copper strips that detect the induced charge from avalanches created in the streamer tube wires. All the Z-planes needed for the upgrade have already been constructed, but only a third of the planes were installed last summer. After installing the 24 Z-planes last year, it was learned that 0.7% of the strips were dead when put inside the detector. This was mainly due to the delicate solder joint between the read-out cable and the strip, and since it is difficult to access or replace the Z-planes inside the detector, it is very important to perform various tests to make sure that the Z-planes will be efficient and effective in the long term. We measure the capacitance between the copper strips and the ground plane, and compare it to the theoretical value that we expect. Instead of measuring the capacitance channel by channel, which would be a very tedious job, we developed a more effective method of measuring the capacitance. Since all the Z-planes were built at SLAC, we also built a smaller 46 cm by 30 cm Z-plane with 12 strips just to see how they were constructed and to gain a better understanding about the solder joints

  19. Relationship Between 24-Hour Ambulatory Central Systolic Blood Pressure and Left Ventricular Mass: A Prospective Multicenter Study.

    Science.gov (United States)

    Weber, Thomas; Wassertheurer, Siegfried; Schmidt-Trucksäss, Arno; Rodilla, Enrique; Ablasser, Cornelia; Jankowski, Piotr; Lorenza Muiesan, Maria; Giannattasio, Cristina; Mang, Claudia; Wilkinson, Ian; Kellermair, Jörg; Hametner, Bernhard; Pascual, Jose Maria; Zweiker, Robert; Czarnecka, Danuta; Paini, Anna; Salvetti, Massimo; Maloberti, Alessandro; McEniery, Carmel

    2017-12-01

    We investigated the relationship between left ventricular mass and brachial office as well as brachial and central ambulatory systolic blood pressure in 7 European centers. Central systolic pressure was measured with a validated oscillometric device, using a transfer function, and mean/diastolic pressure calibration. M-mode images were obtained by echocardiography, and left ventricular mass was determined by one single reader blinded to blood pressure. We studied 289 participants (137 women) free from antihypertensive drugs (mean age: 50.8 years). Mean office blood pressure was 145/88 mm Hg and mean brachial and central ambulatory systolic pressures were 127 and 128 mm Hg, respectively. Mean left ventricular mass was 93.3 kg/m 2 , and 25.6% had left ventricular hypertrophy. The correlation coefficient between left ventricular mass and brachial office, brachial ambulatory, and central ambulatory systolic pressure was 0.29, 0.41, and 0.47, respectively ( P =0.003 for comparison between brachial office and central ambulatory systolic pressure and 0.32 for comparison between brachial and central ambulatory systolic pressure). The results were consistent for men and women, and young and old participants. The areas under the curve for prediction of left ventricular hypertrophy were 0.618, 0.635, and 0.666 for brachial office, brachial, and central ambulatory systolic pressure, respectively ( P =0.03 for comparison between brachial and central ambulatory systolic pressure). In younger participants, central ambulatory systolic pressure was superior to both other measurements. Central ambulatory systolic pressure, measured with an oscillometric cuff, shows a strong trend toward a closer association with left ventricular mass and hypertrophy than brachial office/ambulatory systolic pressure. URL: https://www.clinicaltrials.gov. Unique identifier: NCT01278732. © 2017 American Heart Association, Inc.

  20. Hyperglycemia acutely lowers the postprandial excursions of glucagon-like Peptide-1 and gastric inhibitory polypeptide in humans

    DEFF Research Database (Denmark)

    Vollmer, Kirsten; Gardiwal, Husai; Menge, Bjoern A

    2009-01-01

    INTRODUCTION: Impaired secretion of glucagon-like peptide 1 (GLP-1) has been suggested to contribute to the deficient incretin effect in patients with type 2 diabetes. It is unclear whether this is a primary defect or a consequence of the hyperglycemia in type 2 diabetes. We examined whether acute...... hyperglycemia reduces the postprandial excursions of gastric inhibitory polypeptide (GIP) and GLP-1, and if so, whether this can be attributed to changes in gastric emptying. PATIENTS AND METHODS: Fifteen nondiabetic individuals participated in a euglycemic clamp and a hyperglycemic clamp experiment, carried...... the hyperglycemic clamp experiments and 83 +/- 3 mg/dl during the euglycemia (P hyperglycemia, but meal ingestion led to a decline in glucose requirements in both experiments (P

  1. Investigation on the effect of temperature excursion on the helium defects of tungsten surface by using compact plasma device

    International Nuclear Information System (INIS)

    Takamura, S.; Miyamoto, T.; Tomida, Y.; Minagawa, T.; Ohno, N.

    2011-01-01

    The effects of temperature excursion on the helium defects of tungsten surface have been investigated by using compact plasma device AIT-PID (Aichi Institute of Technology - Plasma Irradiation Device). An initial stage of bubble formation has been identified with an order of smaller (sub-micron) bubbles and holes than those in the past in which the micron size is the standard magnitude. The radiation cooling has been detected when a blacking of tungsten surface coming from nanostructure formation is proceeding due to an increase in the emissivity. The temperature increase to the domain (∼1600 K) in bubble/hole formation from that in nanostructure formation has been found to bring a constriction in diameter and a reduction in length of fiber-form nanostructure.

  2. Evaluation of postprandial glucose excursion using a novel minimally invasive glucose area-under-the-curve monitoring system.

    Science.gov (United States)

    Kuranuki, Sachi; Sato, Toshiyuki; Okada, Seiki; Hosoya, Samiko; Seko, Akinobu; Sugihara, Kaya; Nakamura, Teiji

    2013-01-01

    To develop a minimally invasive interstitial fluid extraction technology (MIET) to monitor postprandial glucose area under the curve (AUC) without blood sampling, we evaluated the accuracy of glucose AUC measured by MIET and compared with that by blood sampling after food intake. Interstitial fluid glucose AUC (IG-AUC) following consumption of 6 different types of foods was measured by MIET. MIET consisted of stamping microneedle arrays, placing hydrogel patches on the areas, and calculating IG-AUC based on glucose levels in the hydrogels. Glycemic index (GI) was determined using IG-AUC and reference AUC measured by blood sampling. IG-AUC strongly correlated with reference AUC (R = 0.91), and GI determined using IG-AUC showed good correlation with that determined by reference AUC (R = 0.88). IG-AUC obtained by MIET can accurately predict the postprandial glucose excursion without blood sampling. In addition, feasibility of GI measurement by MIET was confirmed.

  3. Total flying hours and risk of high systolic blood pressure in the civilian pilot in Indonesia

    Directory of Open Access Journals (Sweden)

    Ferdi Afian

    2016-07-01

    Full Text Available Abstrak Latar belakang: Tekanan darah sistolik tinggi di antara pilot sipil antara lain akan menyebabkan gangguan kardiovaskular sehingga akan mengganggu kelancaran penerbangan. Tujuan penelitian ini ialah untuk mengetahui faktor-faktor dominan terhadap tekanan darah sistolik tinggi pada pilot sipil. Metode: Penelitian potong lintang dengan metode sampling purposif pada pilot yang melakukan pemeriksaan kesehatan berkala di Balai Kesehatan Penerbangan pada tanggal 18-29 Mei 2015. Data yang dikumpulkan adalah karakteristik demografi dan pekerjaan, klinis, kebiasaan olahraga, kebiasaan makan, indeks massa tubuh dan riwayat penyakit. Tekanan darah sistolik tinggi ialah tekanan darah sistolik140 mmHg atau lebih. Hasil: Dari 690 pilot yang melakukan pemeriksaan kesehatan berkala, 428 pilot laki-laki bersedia berpartisipasi mengikuti penelitian ini. Usia dan riwayat penyakit hipertensi merupakan faktor risiko dominan yang berhubungan dengan tekanan darah sistolik tinggi. Jika dibandingkan dengan pilot usia 19-39 tahun, yang berusia 40-65 tahun mempunyai 15,1 kali lipat lebih besar risiko terkena tekanan darah sistolik tinggi [rasio odds suaian (ORa= 15,12; p= 0,001]. Pilot dengan riwayat penyakit hipertensi dibandingkan dengan yang tidak ada riwayat memiliki risiko tekanan darah sistolik tinggi 93,2 kali lipat lebih besar (ORa= 93,21; p= 0,001 Kesimpulan: Usia 40-65 tahun dan memiliki riwayat hipertensi meningkatkan risiko tekanan darah sistolik tinggi di antara pilot sipil di Indonesia. Kata kunci: tekanan darah sistolik, total jam terbang, pilot sipil, Indonesia.  Abstract Background: Systolic high blood pressure among civilian pilots among others will cause cardiovascular disease and this condition will disrupt the flight.The purpose of this study was to identified the dominant factors related to high systolic blood pressure in the civilian pilots. Methods: A cross-sectional study with a purposive sampling method on a pilot who performed periodic

  4. Validation of the Serpent 2-DYNSUB code sequence using the Special Power Excursion Reactor Test III (SPERT III)

    International Nuclear Information System (INIS)

    Knebel, Miriam; Mercatali, Luigi; Sanchez, Victor; Stieglitz, Robert; Macian-Juan, Rafael

    2016-01-01

    Highlights: • Full few-group cross section tables created by Monte Carlo lattice code Serpent 2. • Serpent 2 group constant methodology verified for HFP static and transient cases. • Serpent 2-DYNSUB tool chainvalidated using SPERT III REA experiments. • Serpent 2-DYNSUB tool chain suitable to model RIAs in PWRs. - Abstract: The Special Power Excursion Reactor Test III (SPERT III) is studied using the Serpent 2-DYNSUB code sequence in order to validate it for modeling reactivity insertion accidents (RIA) in PWRs. The SPERT III E-core was a thermal research reactor constructed to analyze reactor dynamics. Its configuration resembles a commercial PWR on terms of fuel type, choice of moderator, coolant flow and system pressure. The initial conditions of the rod ejection accident experiments (REA) performed cover cold startup, hot startup, hot standby and operating power scenarios. Eight of these experiments were analyzed in detail. Firstly, multi-dimensional nodal diffusion cross section tables were created for the three-dimensional reactor simulator DYNSUB employing the Monte Carlo neutron transport code Serpent 2. In a second step, DYNSUB stationary simulations were compared to Monte Carlo reference three-dimensional full scale solutions obtained with Serpent 2 (cold startup conditions) and Serpent 2/SUBCHANFLOW (operating power conditions) with a good agreement being observed. The latter tool is an internal coupling of Serpent 2 and the sub-channel thermal-hydraulics code SUBCHANFLOW. Finally, DYNSUB was utilized to study the eight selected transient experiments. Results were found to match measurements well. As the selected experiments cover much of the possible transient (delayed super-critical, prompt super-critical and super-prompt critical excursion) and initial conditions (cold and hot as well as zero, little and full power reactor states) one expects in commercial PWRs, the obtained results give confidence that the Serpent 2-DYNSUB tool chain is

  5. Slip patterns and preferred dislocation boundary planes

    DEFF Research Database (Denmark)

    Winther, G.

    2003-01-01

    The planes of deformation induced extended planar dislocation boundaries are analysed in two different co-ordinate systems, namely the macroscopic system defined by the deformation axes and the crystallographic system given by the crystallographic lattice. The analysis covers single and polycryst......The planes of deformation induced extended planar dislocation boundaries are analysed in two different co-ordinate systems, namely the macroscopic system defined by the deformation axes and the crystallographic system given by the crystallographic lattice. The analysis covers single...... and polycrystals of fcc metals in three deformation modes (rolling, tension and torsion). In the macroscopic system, boundaries lie close to the macroscopically most stressed planes. In the crystallographic system, the boundary plane depends on the grain/crystal orientation. The boundary planes in both co......-ordinate systems are rationalised based on the slip. The more the slip is concentrated on a slip plane, the closer the boundaries lie to this. The macroscopic preference arises from the macroscopic directionality of the slip. The established relations are applied to (a) prediction of boundary planes from slip...

  6. Adding serial N-terminal pro brain natriuretic peptide measurements to optimal clinical management in outpatients with systolic heart failure

    DEFF Research Database (Denmark)

    Schou, Morten; Gustafsson, Finn; Videbaek, Lars

    2013-01-01

    AIMS: This study was designed to evaluate a new NT-proBNP monitoring concept in outpatients with systolic heart failure (HF). METHODS AND RESULTS: This was a multicentre, prospective randomized open-label blinded endpoint study. A total of 407 systolic HF patients were allocated to either clinical...

  7. Contributions of social context to blood pressure: findings from a multilevel analysis of social capital and systolic blood pressure.

    Science.gov (United States)

    Hamano, Tsuyoshi; Fujisawa, Yoshikazu; Yamasaki, Masayuki; Ito, Katsuhisa; Nabika, Toru; Shiwaku, Kuninori

    2011-06-01

    In recent years, few studies have quantified the effect of residential context on blood pressure. Although these studies have emphasized the importance of socioeconomic influences such as education or poverty levels, the association between the features of social structure such as social capital and blood pressure remain unclear. Therefore, we investigated whether social capital was associated with systolic blood pressure after controlling for individual potential confounders. We analyzed data from the Shimane Study conducted from 2006 to 2008 in rural mountainous regions of Japan. After excluding the missing data and data of participants taking hypertension medication, we conducted a multilevel analysis of the data for 335 individuals nested within 30 postcode sectors. Systolic blood pressure increased with increasing age and body mass index. We also found that a higher systolic blood pressure was observed among smokers and those taking medication for diabetes. Regarding the contextual effects of social capital, systolic blood pressure increased with an increasing proportion of lack of fairness, after adjustment for individual confounders. To the best of our knowledge, this study is the first to investigate the association between social capital and systolic blood pressure by using a multilevel methodological framework. Surprisingly, we found that lack of fairness had a strong effect on systolic blood pressure. However, we could not find any significant associations between other items of social capital and systolic blood pressure. Further studies are needed to clarify the mechanism by which lack of fairness may have an effect on systolic blood pressure.

  8. Forward coronary flow normally seen in systole is the result of both forward and concealed back flow

    NARCIS (Netherlands)

    Spaan, J. A.; Breuls, N. P.; Laird, J. D.

    1981-01-01

    Normally systolic coronary blood flow is almost entirely forward. As perfusion pressure was lowered through the autoregulatory range in open-chest dogs, net systolic back flow appeared at approximately 70 mm Hg. Imposing a series resistance (Rs), which impedes both forward and back flow, abolished

  9. End-systolic stress-velocity relation and circumferential fiber velocity shortening for analysing left ventricular function in mice

    Energy Technology Data Exchange (ETDEWEB)

    Fayssoil, A. [Cardiologie, Hopital europeen Georges Pompidou, 20, rue le blanc, Paris (France)], E-mail: fayssoil2000@yahoo.fr; Renault, G. [CNRS UMR 8104, Inserm, U567, Institut Cochin, Universite Paris Descartes, Paris (France); Fougerousse, F. [Genethon, RD, Evry (France)

    2009-08-15

    Traditionally, analysing left ventricular (LV) performance relies on echocardiography by evaluating shortening fraction (SF) in mice. SF is influenced by load conditions. End-systolic stress-velocity (ESSV) relation and circumferential fiber velocity (VcF) shortening are more relevant parameters for evaluating systolic function regardless load conditions particularly in mice's models of heart failure.

  10. In-plane and cross-plane thermal conductivities of molybdenum disulfide

    International Nuclear Information System (INIS)

    Ding, Zhiwei; Pei, Qing-Xiang; Zhang, Yong-Wei; Jiang, Jin-Wu

    2015-01-01

    We investigate the in-plane and cross-plane thermal conductivities of molybdenum disulfide (MoS 2 ) using non-equilibrium molecular dynamics simulations. We find that the in-plane thermal conductivity of monolayer MoS 2 is about 19.76 W mK −1 . Interestingly, the in-plane thermal conductivity of multilayer MoS 2 is insensitive to the number of layers, which is in strong contrast to the in-plane thermal conductivity of graphene where the interlayer interaction strongly affects the in-plane thermal conductivity. This layer number insensitivity is attributable to the finite energy gap in the phonon spectrum of MoS 2 , which makes the phonon–phonon scattering channel almost unchanged with increasing layer number. For the cross-plane thermal transport, we find that the cross-plane thermal conductivity of multilayer MoS 2 can be effectively tuned by applying cross-plane strain. More specifically, a 10% cross-plane compressive strain can enhance the thermal conductivity by a factor of 10, while a 5% cross-plane tensile strain can reduce the thermal conductivity by 90%. Our findings are important for thermal management in MoS 2 based nanodevices and for thermoelectric applications of MoS 2 . (paper)

  11. Influence of mandibular fixation method on stability of the maxillary occlusal plane after occlusal plane alteration.

    Science.gov (United States)

    Yosano, Akira; Katakura, Akira; Takaki, Takashi; Shibahara, Takahiko

    2009-05-01

    In this study, we investigated how method of mandibular fixation influenced longterm postoperative stability of the maxilla in Class III cases. In particular, we investigated change in the maxillary occlusal plane after Occlusal Plane Alteration. Therefore, we focused on change in the palatal plane to evaluate stability of the maxillary occlusal plane, as the position of the palatal plane affects the maxillary occlusal plane. This study included 16 patients diagnosed with mandibular protrusion. Alteration of the occlusal plane was achieved by clockwise rotation of the maxilla by Le Fort I osteotomy and mandibular setback was performed by bilateral sagittal split ramus osteotomy. We analyzed and examined lateral cephalometric radiographs taken at 1 month, 3 months, 6 months, and 1 year after surgery. Stability achieved by two methods of mandibular fixation was compared. In one group of patients (group S) titanium screws were used, and in the other group (group P) titanium-locking mini-plates were used. No significant displacement was recognized in group S, whereas an approximately 0.7mm upward vertical displacement was recognized in the anterior nasal spine in group P. As a result, not only the angle of the palatal plane and S-N plane, but also occlusal plane angle in group P showed a greater decrease than that in group S. The results suggest that fixing the mandible with screws yielded greater stability of the maxilla and maxillary occlusal plane than fixing the mandible with titanium plates.

  12. 8-isorpostanes – markers for oxidative stress in obstructive sleep apnea patients with systolic dysfunction

    Directory of Open Access Journals (Sweden)

    Cherneva RV

    2013-06-01

    Full Text Available Radostina Vlaeva Cherneva,1 Ognian Borisov Georgiev,1 Daniela Stoichkova Petrova,1 Emil Ivanov Manov,2 Sylvia Rumenova Ruseva,3 Vanio Ivanov Mitev,3 Julia Ivanova Petrova4 1Department of Internal Medicine, Division of Pulmonary Medicine, Medical University of Sofia, Sofia, Bulgaria; 2Department of Internal Medicine, Division of Cardiology, Medical University of Sofia, Sofia, Bulgaria; 3Department of Medical Chemistry and Biochemistry, Laboratory of Synthesis and Analysis of Bioactive Substances, Medical University of Sofia, Sofia, Bulgaria; 4Department of Neurology, Medical University of Sofia, Sofia, Bulgaria Objective: Increased oxidative stress is considered to be an independent risk factor for cardiovascular diseases, but remains disputed in obstructive sleep apnea (OSA. Among oxidative stress markers, isorpostanes are considered to be the most sensitive and specific. Aims: The aim of the study was to compare urinary isorpostanes in patients with OSA and systolic dysfunction to patients with OSA and preserved ejection fraction (EF and determine their role as markers for increased oxidative stress and early cardiac damage. Materials and methods: Urinary 8F2-isorpostanes were measured in 30 patients with OSA and mild systolic dysfunction (EF = 45.7% ± 6.17% and compared to 15 patients with OSA and normal EF (EF = 60.3% ± 6.3%. Univariate regression analysis was performed to find predictors of left systolic dysfunction. Correlations between 8-isorpostanes, anthropometric, metabolic, and sleep study characteristics were explored. In addition, in 19 patients the effect of bilevel positive airway pressure (BiPAP therapy was evaluated during a 3 month follow-up. Markers of hemodynamic stress, N-terminal prohormone of brain natriuretic peptide and oxidative stress, measured by 8-isorpostanes were compared before and after the follow-up. Results: Urinary levels of 8-isorpostanes were significantly higher in the group with mild systolic dysfunction

  13. The influence of heel height on sagittal plane knee kinematics during landing tasks in recreationally active and athletic collegiate females.

    Science.gov (United States)

    Lindenberg, Kelly M; Carcia, Christopher R; Phelps, Amy L; Martin, Robroy L; Burrows, Anne M

    2011-09-01

    To determine if heel height alters sagittal plane knee kinematics when landing from a forward hop or drop landing. Knee angles close to extension during landing are theorized to increase ACL injury risk in female athletes. Fifty collegiate females performed two single-limb landing tasks while wearing heel lifts of three different sizes (0, 12 & 24 mm) attached to the bottom of a sneaker. Using an electrogoniometer, sagittal plane kinematics (initial contact [KA(IC)], peak flexion [KA(Peak)], and rate of excursion [RE]) were examined. Repeated measures ANOVAs were used to determine the influence of heel height on the dependent measures. Forward hop task- KA(IC) with 0 mm, 12 mm, and 24 mm lifts were 8.88±6.5, 9.38±5.8 and 11.28±7.0, respectively. Significant differences were noted between 0 and 24 mm lift (psneaker significantly alters sagittal plane knee kinematics upon landing from a unilateral forward hop but not from a drop jump.

  14. Streptococcus anginosus infections: crossing tissue planes.

    Science.gov (United States)

    Sunwoo, Bernie Y; Miller, Wallace T

    2014-10-01

    Streptococcus anginosus has long been recognized to cause invasive pyogenic infections. This holds true for thoracic infections where S. anginosus has a propensity for abscess and empyema formation. Early diagnosis is important given the significant morbidity and mortality associated with thoracic S. anginosus infections. Yet, distinguishing thoracic S. anginosus clinically is difficult. We present three cases of thoracic S. anginosus that demonstrated radiographic extension across tissue planes, including the interlobar fissure, diaphragm, and chest wall. Few infectious etiologies are known to cross tissue planes. Accordingly, we propose S. anginosus be considered among the differential diagnosis of potential infectious etiologies causing radiographic extension across tissue planes.

  15. Optically sectioned imaging by oblique plane microscopy

    Science.gov (United States)

    Kumar, Sunil; Lin, Ziduo; Lyon, Alex R.; MacLeod, Ken T.; Dunsby, Chris

    2011-03-01

    Oblique Plane Microscopy (OPM) is a light sheet microscopy technique that combines oblique illumination with correction optics that tilt the focal plane of the collection system. OPM can be used to image conventionally mounted specimens on coverslips or tissue culture dishes and has low out-of-plane photobleaching and phototoxicity. No moving parts are required to achieve an optically sectioned image and so high speed optically sectioned imaging is possible. The first OPM results obtained using a high NA water immersion lens on a commercially available inverted microscope frame are presented, together with a measurement of the achievable optical resolution.

  16. Excursions out-of-lane versus standard deviation of lateral position as outcome measure of the on-the-road driving test

    NARCIS (Netherlands)

    Verster, Joris C; Roth, Thomas

    BACKGROUND: The traditional outcome measure of the Dutch on-the-road driving test is the standard deviation of lateral position (SDLP), the weaving of the car. This paper explores whether excursions out-of-lane are a suitable additional outcome measure to index driving impairment. METHODS: A

  17. Students' Long-Term Memories from an Ecology Field Excursion: Retelling a Narrative as an Interplay between Implicit and Explicit Memories

    Science.gov (United States)

    Stolpe, Karin; Bjorklund, Lars

    2013-01-01

    This study aims to investigate the science content remembered by biology students 6 and 12 months after an ecology excursion. The students' memories were tested during a stimulated recall interview. The authors identified three different types of memories: "recall," "recognition" and "narratives." The "dual…

  18. Prognostic implications of left ventricular diastolic dysfunction with preserved systolic function following acute myocardial infarction

    DEFF Research Database (Denmark)

    Poulsen, S H; Møller, J E; Nørager, B

    2001-01-01

    of the mitral and pulmonary venous flow, and the propagation velocity of early mitral flow by color M-mode Doppler echocardiography in 183 consecutive patients at day 5-7 following their first acute MI. Patients were classified into four groups: group A: preserved LV systolic and diastolic function (n = 73......%) and D (38%) compared to A (2%) (p class >or=II (p = 0.006), and age (0.008) as predictors of cardiac death or readmission due to heart failure. The presence of LV diastolic dysfunction with preserved......The contribution of diastolic dysfunction in patients with preserved left ventricular (LV) systolic function to impaired functional status and cardiac mortality in myocardial infarction (MI) is unknown. In the present study, assessment of LV diastolic function was performed by Doppler analysis...

  19. Effect of hematocrit and systolic blood pressure on cerebral blood flow in newborn infants

    International Nuclear Information System (INIS)

    Younkin, D.P.; Reivich, M.; Jaggi, J.L.; Obrist, W.D.; Delivoria-Papadopoulos, M.

    1987-01-01

    The effects of hematocrit and systolic blood pressure on cerebral blood flow were measured in 15 stable, low birth weight babies. CBF was measured with a modification of the xenon-133 ( 133 Xe) clearance technique, which uses an intravenous bolus of 133 Xe, an external chest detector to estimate arterial 133 Xe concentration, eight external cranial detectors to measure cephalic 133 Xe clearance curves, and a two-compartmental analysis of the cephalic 133 Xe clearance curves to estimate CBF. There was a significant inverse correlation between hematocrit and CBF, presumably due to alterations in arterial oxygen content and blood viscosity. Newborn CBF varied independently of systolic blood pressure between 60 and 84 mm Hg, suggesting an intact cerebrovascular autoregulatory mechanism. These results indicate that at least two of the factors that affect newborn animal CBF are operational in human newborns and may have important clinical implications

  20. Long-term L-Triiodothyronine (T3) treatment in stable systolic heart failure patients

    DEFF Research Database (Denmark)

    Holmager, Pernille; Schmidt, Ulla; Mark, Peter

    2015-01-01

    %, range: 37-52 and serum T3 levels 1·4 nmol/l (0·9-1·6). The T3 dose was 20 μg per day (10-40). TSH levels did not change between groups, whereas serum T3 levels increased in the active arm. Cardiac function as measured by LVEF, end-diastolic and end-systolic volumes and cardiac output did not change...... during T3-treatment and neither did the neurohormonal profile. There were no side-effects in terms of cardiac arrhythmias and no change in resting heart rate. CONCLUSIONS: This study does not support the hypothesis that oral T3 treatment might be beneficial to patients with chronic, stable systolic HF...

  1. Causal inheritance in plane wave quotients

    International Nuclear Information System (INIS)

    Hubeny, Veronika E.; Rangamani, Mukund; Ross, Simon F.

    2003-01-01

    We investigate the appearance of closed timelike curves in quotients of plane waves along spacelike isometries. First we formulate a necessary and sufficient condition for a quotient of a general spacetime to preserve stable causality. We explicitly show that the plane waves are stably causal; in passing, we observe that some pp-waves are not even distinguishing. We then consider the classification of all quotients of the maximally supersymmetric ten-dimensional plane wave under a spacelike isometry, and show that the quotient will lead to closed timelike curves iff the isometry involves a translation along the u direction. The appearance of these closed timelike curves is thus connected to the special properties of the light cones in plane wave spacetimes. We show that all other quotients preserve stable causality

  2. Lieb's correlation inequality for plane rotors

    International Nuclear Information System (INIS)

    Rivasseau, V.

    1980-01-01

    We prove a conjecture by E. Lieb, which leads to the Lieb inequality for plane rotors. As in the Ising model case, this inequality implies the existence of an algorithm to compute the transition temperature of this model. (orig.)

  3. Titanium Heat Pipe Thermal Plane, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — The objective of the Phase II program is to complete the development of the titanium heat pipe thermal plane and establish all necessary steps for production of this...

  4. Null-plane quantization of fermions

    International Nuclear Information System (INIS)

    Mustaki, D.

    1990-01-01

    Massive Dirac fermions are canonically quantized on the null plane using the Dirac-Bergmann algorithm. The procedure is carried out in the framework of quantum electrodynamics as an illustration of a rigorous treatment of interacting fermion fields

  5. Some Features of the Plane Couette Flow

    National Research Council Canada - National Science Library

    Skovorodko, Petr

    2000-01-01

    In the previous paper 1 it was found, in particular, that in the transition regime of the plane Couette flow the values of total energy flux and shear stress may exceed the corresponding free molecular values...

  6. Causal inheritance in plane wave quotients

    Science.gov (United States)

    Hubeny, Veronika E.; Rangamani, Mukund; Ross, Simon F.

    2004-01-01

    We investigate the appearance of closed timelike curves in quotients of plane waves along spacelike isometries. First we formulate a necessary and sufficient condition for a quotient of a general space-time to preserve stable causality. We explicitly show that the plane waves are stably causal; in passing, we observe that some pp waves are not even distinguishing. We then consider the classification of all quotients of the maximally supersymmetric ten-dimensional plane wave under a spacelike isometry, and show that the quotient will lead to closed timelike curves iff the isometry involves a translation along the u direction. The appearance of these closed timelike curves is thus connected to the special properties of the light cones in plane wave space-times. We show that all other quotients preserve stable causality.

  7. Effects of parental smoking on exercise systolic blood pressure in adolescents.

    Science.gov (United States)

    Hacke, Claudia; Weisser, Burkhard

    2015-05-11

    In adults, exercise blood pressure seems to be more closely related to cardiovascular risk than resting blood pressure; however, few data are available on the effects of familial risk factors, including smoking habits, on exercise blood pressure in adolescents. Blood pressure at rest and during exercise, parental smoking, and other familial risk factors were investigated in 532 adolescents aged 12 to 17 years (14.6±1.5 years) in the Kiel EX.PRESS. (EXercise PRESSure) Study. Exercise blood pressure was determined at 1.5 W/kg body weight using a standardized submaximal cycle ergometer test. Mean resting blood pressure was 113.1±12.8/57.2±7.1 mm Hg, and exercise blood pressure was 149.9±19.8/54.2±8.6 mm Hg. Parental smoking increased exercise systolic blood pressure (+4.0 mm Hg, 3.1 to 4.9; P=0.03) but not resting blood pressure of the subjects (adjusted for age, sex, height, body mass index percentile, fitness). Parental overweight and familial hypertension were related to both higher resting and exercise systolic blood pressure values, whereas associations with an inactive lifestyle and a low educational level of the parents were found only with adolescents' blood pressure during exercise. The cumulative effect of familial risk factors on exercise systolic blood pressure was more pronounced than on blood pressure at rest. Parental smoking might be a novel risk factor for higher blood pressure, especially during exercise. In addition, systolic blood pressure during a submaximal exercise test was more closely associated with familial risk factors than was resting blood pressure, even in adolescents. © 2015 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell.

  8. The effect of chronic digitalization on pump function in systolic heart failure.

    Science.gov (United States)

    Hassapoyannes, C A; Easterling, B M; Chavda, K; Chavda, K K; Movahed, M R; Welch, G W

    2001-10-01

    Short- and intermediate-term use of cardiac glycosides promotes inotropy and improves the ejection fraction in systolic heart failure. To determine whether chronic digitalization alters left ventricular function and performance. Eighty patients with mild-to-moderate systolic heart failure (baseline ejection fraction < or =45%) participated from our institution in a multi-center, chronic, randomized, double-blind study of digitalis vs. placebo. Of the 40 survivors, 38 (20 allocated to the digitalis arm and 18 to the placebo arm) were evaluated at the end of follow-up (mean, 48.4 months). Left ventricular systolic function was assessed by both nuclear ventriculography and echocardiography. The ejection fraction was measured scintigraphically, while the ventricular volumes were computed echocardiographically. The groups did not differ, at baseline or end-of-study, with respect to the ejection fraction and the loading conditions (arterial pressure, ventricular volumes and heart rate) by either intention-to-treat or actual-treatment-received analysis. Over the course of the trial, the digitalis arm exhibited no significant increase in the use of diuretics (18%, P=0.33), in distinction from the placebo group (78%, P=0.004), and a longer stay on study drug among those patients who withdrew from double-blind treatment (28.6 vs. 11.4 months, P=0.01). Following chronic use of digitalis for mild-to-moderate heart failure, cross-sectional comparison with a control group from the same inception cohort showed no appreciable difference in systolic function or performance. Thus, the suggested clinical benefit cannot be explained by an inotropic effect.

  9. Mitral Regurgitation Severity and Left Ventricular Systolic Dimension Predict Survival in Young Cavalier King Charles Spaniels

    DEFF Research Database (Denmark)

    Reimann, M. J.; Moller, J. E.; Haggstrom, J.

    2017-01-01

    Background Development and progression of myxomatous mitral valve disease (MMVD) in dogs are difficult to predict. Identification at a young age of dogs at high risk of adverse outcome in the future is desirable. Hypothesis/Objectives To study the predictive value of selected clinical.......016) mortality increased with increasing left ventricular end-systolic internal dimension normalized for body weight (LVIDSN). Conclusions and clinical importance Moderate to severe MR, even if intermittent, and increased LVIDSN in dogs

  10. Analysis of end-systolic pressure-volume relation by gated radionuclide angiocardiography

    International Nuclear Information System (INIS)

    Adachi, Haruhiko; Sugihara, Horoki; Katsume, Hiroshi; Ijichi, Hamao; Miyanaga, Hajime

    1982-01-01

    Left ventricular end-systolic pressure-volume relation has been proved experimentally to b e an useful index of left ventricular contractility relatively independent of preload or afterload. But less clinical application has been reported because of its invasive nature, and we evaluated this relationship non-invasively using gated radionuclide angiocardiography as volume determination and cuff sphyngomanometer in the arm as pressure measurement. Gated equilibrium blood pool scintigrams were obtained at rest and during intravenous infusion of angiotensin or nitrate. Ventricular volumes were derived from ventricular activity and peripheral blood volume and activity. The peak systolic pressure (PSP) by cuff method to end-systolic volume index (ESVI) relations showed good linearity (r gt .930 in 84% of consecutive 50 cases) and were gentler in the groups with more impaired left ventricular function. Emax was related exponentially to ejection fraction (EF) and hyperbolically to end-diastolic volume index. The dead volume (VoI) was unfixed and fell into positive or negative value, and was not related to EF under control condition. PSP/ESVI in each loading condition was less variable with the alteration of blood pressure than EF. The linear relation was found between PSP/ESVI under control condition and Emax (PSP/ESVI = 0.651.Emax + 0.958, r = 0.841, p lt .001). Thus in measuring ventricular volume, gated radionuclide angiocardiography is a non-invasive method less affected by the geometry of the left ventricle. Non-invasive determination of end-systolic pressure-volume relation using the volume by radionuclide and the blood pressure by cuff method is clinically useful in the assessment of left ventricular contractility. (author)

  11. Automatic detection of end-diastolic and end-systolic frames in 2D echocardiography.

    Science.gov (United States)

    Zolgharni, Massoud; Negoita, Madalina; Dhutia, Niti M; Mielewczik, Michael; Manoharan, Karikaran; Sohaib, S M Afzal; Finegold, Judith A; Sacchi, Stefania; Cole, Graham D; Francis, Darrel P

    2017-07-01

    Correctly selecting the end-diastolic and end-systolic frames on a 2D echocardiogram is important and challenging, for both human experts and automated algorithms. Manual selection is time-consuming and subject to uncertainty, and may affect the results obtained, especially for advanced measurements such as myocardial strain. We developed and evaluated algorithms which can automatically extract global and regional cardiac velocity, and identify end-diastolic and end-systolic frames. We acquired apical four-chamber 2D echocardiographic video recordings, each at least 10 heartbeats long, acquired twice at frame rates of 52 and 79 frames/s from 19 patients, yielding 38 recordings. Five experienced echocardiographers independently marked end-systolic and end-diastolic frames for the first 10 heartbeats of each recording. The automated algorithm also did this. Using the average of time points identified by five human operators as the reference gold standard, the individual operators had a root mean square difference from that gold standard of 46.5 ms. The algorithm had a root mean square difference from the human gold standard of 40.5 ms (P<.0001). Put another way, the algorithm-identified time point was an outlier in 122/564 heartbeats (21.6%), whereas the average human operator was an outlier in 254/564 heartbeats (45%). An automated algorithm can identify the end-systolic and end-diastolic frames with performance indistinguishable from that of human experts. This saves staff time, which could therefore be invested in assessing more beats, and reduces uncertainty about the reliability of the choice of frame. © 2017, Wiley Periodicals, Inc.

  12. Measurement of pulmonary arterial elastance in patients with systolic heart failure using Doppler echocardiography

    Science.gov (United States)

    Taghavi, Sepideh; Esmaeilzadeh, Maryam; Amin, Ahmad; Naderi, Nasim; Abkenar, Hooman Bakhshandeh; Maleki, Majid; Mitra, Chitsazan

    2016-01-01

    Objective: A reliable and easy-to-perform method for measuring right ventricular (RV) afterload is desirable when scheduling patients with systolic heart failure to undergo heart transplantation. The present study aimed to investigate the accuracy of echocardiographically-derived pulmonary arterial elastance as a measurement of pulmonary vascular resistance by comparing it with invasive measures. Methods: Thirty-one patients with moderate to severe systolic heart failure, including 22 (71%) male patients, with a mean age of 41.16±15.9 years were enrolled in the study. Right heart catheterization and comprehensive echocardiography during the first hour after completion of cardiac catheterization were performed in all the patients. The pulmonary artery elastance was estimated using the ratio of end-systolic pressure (Pes) over the stroke volume (SV) by both cardiac catheterization [Ea (PV)-C] and echocardiography [Ea (PV)-E]. Results: The mean Ea (PV)-C and Ea (PV)-E were estimated to be 0.73±0.49 mm Hg/mL and 0.67±0.44 mm Hg/mL, respectively. There was a significant relation between Ea (PV)-E and Ea (PV)-C (r=0.897, pechocardiography and catheterization methods for estimating Ea (PV), investigated by the Bland-Altman method, showed a mean bias of -0.06, with 95% limits of agreement from -0.36 mm Hg/mL to 0.48 mm Hg/mL. Conclusion: Doppler echocardiography is an easy, non-invasive, and inexpensive method for measuring pulmonary arterial elastance, which provides accurate and reliable estimation of RV afterload in patients with systolic heart failure. PMID:26467379

  13. Significance of white-coat hypertension in older persons with isolated systolic hypertension

    DEFF Research Database (Denmark)

    Franklin, Stanley S; Thijs, Lutgarde; Hansen, Tine W

    2012-01-01

    The significance of white-coat hypertension in older persons with isolated systolic hypertension remains poorly understood. We analyzed subjects from the population-based 11-country International Database on Ambulatory Blood Pressure Monitoring in Relation to Cardiovascular Outcomes database who ...... had daytime ambulatory blood pressure (BP; ABP) and conventional BP (CBP) measurements. After excluding persons with diastolic hypertension by CBP (=90 mm Hg) or by daytime ABP (=85 mm Hg), a history of cardiovascular disease, and persons...

  14. Proof of Polyakov conjecture on supercomplex plane

    International Nuclear Information System (INIS)

    Kachkachi, M.; Kouadik, S.

    1994-10-01

    Using Neumann series, we solve iteratively SBE to arbitrary order. Then applying this, we compute the energy momentum tensor and n points functions for generic n starting from WZP action on the supercomplex plane. We solve the superconformal Ward identity and we show that the iterative solution to arbitrary order is resumed by WZP action. This proves the Polyakov conjecture on supercomplex plane. (author). 8 refs

  15. Constructive curves in non-Euclidean planes

    OpenAIRE

    Horváth, Ákos G.

    2016-01-01

    In this paper we overview the theory of conics and roulettes in four non-Euclidean planes. We collect the literature about these classical concepts, from the eighteenth century to the present, including papers available only on arXiv. The comparison of the four non-Euclidean planes, in terms of the known results on conics and roulettes, reflects only the very subjective view of the author.

  16. Heteroepitaxial growth of basal plane stacking fault free a-plane GaN

    Energy Technology Data Exchange (ETDEWEB)

    Wieneke, Matthias; Hempel, Thomas; Noltemeyer, Martin; Witte, Hartmut; Dadgar, Armin; Blaesing, Juergen; Christen, Juergen; Krost, Alois [Otto-von-Guericke Universitaet Magdeburg, FNW/IEP, Magdeburg (Germany)

    2010-07-01

    Growth of light emitting quantum-wells based on a-plane GaN is a possibility to reduce or even to avoid polarization correlated luminescence red shift and reduction of radiative recombination efficiency. But until now heteroepitaxially grown a-plane GaN films are characterized by a poor crystalline quality expressed by a high density of basal plane stacking faults (BSF) and partial dislocations. We present Si doped a-plane GaN films grown on r-plane sapphire substrates by metal organic vapor phase epitaxy using high temperature AlGaN nucleation layers. FE-SEM images revealed three dimensionally grown GaN crystallites sized up to tenth micrometer in the basal plane and a few tenth micrometers along the c-axes. Though, the full width at half maxima of the X-ray diffraction {omega}-scans of the in-plane GaN(1 anti 100) and GaN(0002) Bragg reflections exhibited a very high crystal quality. Furthermore, luminescence spectra were dominated by near band gap emission, while there was no separated peak of the basal plane stacking fault. In summary we present heteroepitaxially grown a-plane GaN without an evidence of basal plane stacking faults in X-ray diffraction measurements and luminescence spectra.

  17. Optimal algorithm switching for the estimation of systole period from cardiac microacceleration signals (SonR).

    Science.gov (United States)

    Giorgis, L; Frogerais, P; Amblard, A; Donal, E; Mabo, P; Senhadji, L; Hernández, A I

    2012-11-01

    Previous studies have shown that cardiac microacceleration signals, recorded either cutaneously, or embedded into the tip of an endocardial pacing lead, provide meaningful information to characterize the cardiac mechanical function. This information may be useful to personalize and optimize the cardiac resynchronization therapy, delivered by a biventricular pacemaker, for patients suffering from chronic heart failure (HF). This paper focuses on the improvement of a previously proposed method for the estimation of the systole period from a signal acquired with a cardiac microaccelerometer (SonR sensor, Sorin CRM SAS, France). We propose an optimal algorithm switching approach, to dynamically select the best configuration of the estimation method, as a function of different control variables, such as the signal-to-noise ratio or heart rate. This method was evaluated on a database containing recordings from 31 patients suffering from chronic HF and implanted with a biventricular pacemaker, for which various cardiac pacing configurations were tested. Ultrasound measurements of the systole period were used as a reference and the improved method was compared with the original estimator. A reduction of 11% on the absolute estimation error was obtained for the systole period with the proposed algorithm switching approach.

  18. Perceived Social Standing, Medication Nonadherence, and Systolic Blood Pressure in the Rural South.

    Science.gov (United States)

    Cummings, Doyle M; Wu, Jia-Rong; Cene, Crystal; Halladay, Jacquie; Donahue, Katrina E; Hinderliter, Alan; Miller, Cassandra; Garcia, Beverly; Penn, Dolly; Tillman, Jim; DeWalt, Darren

    2016-01-01

    Little is known about how perceived social standing versus traditional socioeconomic characteristics influence medication adherence and blood pressure (BP) among African American and white patients with hypertension in the rural southeastern United States. Perceived social standing, socioeconomic characteristics, self-reported antihypertensive medication adherence, and BP were measured at baseline in a cohort of rural African American and white patients (n = 495) with uncontrolled hypertension attending primary care practices. Multivariate models examined the relationship of perceived social standing and socioeconomic indicators with medication adherence and systolic BP. Medication nonadherence was reported by 40% of patients. Younger age [β = 0.20; P = .001], African American race [β = -0.30; P = .03], and lower perceived social standing [β = 0.08; P = .002] but not sex or traditional socioeconomic characteristics including education and household income, were significantly associated with lower medication adherence. Race-specific analyses revealed that this pattern was limited to African Americans and not observed in whites. In stepwise modeling, older age [β = 0.57, P = .001], African American race [β = 4.4; P = .03], and lower medication adherence [β = -1.7, P = .01] but not gender, education, or household income, were significantly associated with higher systolic BP. Lower perceived social standing and age, but not traditional socioeconomic characteristics, were significantly associated with lower medication adherence in African Americans. Lower medication adherence was associated with higher systolic BP. These findings suggest the need for tailored, culturally relevant medication adherence interventions in rural communities. © 2015 National Rural Health Association.

  19. Automatic detection of end-diastole and end-systole from echocardiography images using manifold learning

    International Nuclear Information System (INIS)

    Gifani, Parisa; Behnam, Hamid; Shalbaf, Ahmad; Sani, Zahra Alizadeh

    2010-01-01

    The automatic detection of end-diastole and end-systole frames of echocardiography images is the first step for calculation of the ejection fraction, stroke volume and some other features related to heart motion abnormalities. In this paper, the manifold learning algorithm is applied on 2D echocardiography images to find out the relationship between the frames of one cycle of heart motion. By this approach the nonlinear embedded information in sequential images is represented in a two-dimensional manifold by the LLE algorithm and each image is depicted by a point on reconstructed manifold. There are three dense regions on the manifold which correspond to the three phases of cardiac cycle ('isovolumetric contraction', 'isovolumetric relaxation', 'reduced filling'), wherein there is no prominent change in ventricular volume. By the fact that the end-systolic and end-diastolic frames are in isovolumic phases of the cardiac cycle, the dense regions can be used to find these frames. By calculating the distance between consecutive points in the manifold, the isovolumic frames are mapped on the three minimums of the distance diagrams which were used to select the corresponding images. The minimum correlation between these images leads to detection of end-systole and end-diastole frames. The results on six healthy volunteers have been validated by an experienced echo cardiologist and depict the usefulness of the presented method

  20. On-Treatment Blood Pressure and Cardiovascular Outcomes in Older Adults With Isolated Systolic Hypertension.

    Science.gov (United States)

    Yano, Yuichiro; Rakugi, Hiromi; Bakris, George L; Lloyd-Jones, Donald M; Oparil, Suzanne; Saruta, Takao; Shimada, Kazuyuki; Matsuoka, Hiroaki; Imai, Yutaka; Ogihara, Toshio

    2017-02-01

    Our aim was to assess optimal on-treatment blood pressure (BP) at which cardiovascular disease (CVD) and all-cause mortality risks are minimized in Japanese older adults with isolated systolic hypertension. We used data from the VALISH study (Valsartan in Elderly Isolated Systolic Hypertension) that recruited older adults (n=3035; mean age, 76 years) with systolic BP (SBP) of ≥160 mm Hg and diastolic BP of secondary outcome being all-cause mortality. Cox proportional hazards models were used to assess the CVD risk for each group. Over a median 3-year follow-up (8022 person-years), 93 CVD events and 52 deaths occurred. Using the on-treatment SBP of 130 to hypertension, SBP in the range between 130 and 144 mm Hg was associated with minimal adverse outcomes and a reduction in CVD and all-cause mortality. The BP range will need to be confirmed in randomized controlled trials. URL: https://www.clinicaltrials.gov. Unique identifier: NCT00151229. © 2017 American Heart Association, Inc.

  1. Quantitative assessment of left ventricular systolic function using 3-dimensional echocardiography

    Directory of Open Access Journals (Sweden)

    Rahul Mehrotra

    2013-09-01

    Full Text Available Assessment of left ventricular systolic function is the commonest and one of the most important indications for performance of echocardiography. It is important for prognostication, determination of treatment plan, for decisions related to expensive device therapies and for assessing response to treatment. The current methods based on two-dimensional echocardiography are not reliable, have high degree of inter-observer and intra-observer variability and are based on presumptions about the geometry of left ventricle (LV. Real-time three-dimensional echocardiography (RT3DE on the other hand is fast, easy, accurate, relatively operator independent and is not based on any assumptions related to the shape of LV. Owing to these advantages, it is the Echocardiographic modality of choice for assessment of systolic function of the LV. We describe here a step by step approach to evaluation of LV volumes, ejection fraction, regional systolic function and Dyssynchrony analysis based on RT3DE. It has been well validated in clinical studies and is rapidly being incorporated in routine clinical practice.

  2. Systolic and Diastolic Left Ventricular Mechanics during and after Resistance Exercise.

    Science.gov (United States)

    Stöhr, Eric J; Stembridge, Mike; Shave, Rob; Samuel, T Jake; Stone, Keeron; Esformes, Joseph I

    2017-10-01

    To improve the current understanding of the impact of resistance exercise on the heart, by examining the acute responses of left ventricular (LV) strain, twist, and untwisting rate ("LV mechanics"). LV echocardiographic images were recorded in systole and diastole before, during and immediately after (7-12 s) double-leg press exercise at two intensities (30% and 60% of maximum strength, one-repetition maximum). Speckle tracking analysis generated LV strain, twist, and untwisting rate data. Additionally, beat-by-beat blood pressure was recorded and systemic vascular resistance (SVR) and LV wall stress were calculated. Responses in both exercise trials were statistically similar (P > 0.05). During effort, stroke volume decreased, whereas SVR and LV wall stress increased (P mechanics (P 0.05). Immediately after exercise, systolic LV mechanics returned to baseline levels (P mechanics, but increases diastolic mechanics after exercise, suggesting that resistance exercise has a differential impact on systolic and diastolic heart muscle function. The findings may explain why acute resistance exercise has been associated with reduced stroke volume but chronic exercise training may result in increased LV volumes.

  3. Two-dimensional systolic-array architecture for pixel-level vision tasks

    Science.gov (United States)

    Vijverberg, Julien A.; de With, Peter H. N.

    2010-05-01

    This paper presents ongoing work on the design of a two-dimensional (2D) systolic array for image processing. This component is designed to operate on a multi-processor system-on-chip. In contrast with other 2D systolic-array architectures and many other hardware accelerators, we investigate the applicability of executing multiple tasks in a time-interleaved fashion on the Systolic Array (SA). This leads to a lower external memory bandwidth and better load balancing of the tasks on the different processing tiles. To enable the interleaving of tasks, we add a shadow-state register for fast task switching. To reduce the number of accesses to the external memory, we propose to share the communication assist between consecutive tasks. A preliminary, non-functional version of the SA has been synthesized for an XV4S25 FPGA device and yields a maximum clock frequency of 150 MHz requiring 1,447 slices and 5 memory blocks. Mapping tasks from video content-analysis applications from literature on the SA yields reductions in the execution time of 1-2 orders of magnitude compared to the software implementation. We conclude that the choice for an SA architecture is useful, but a scaled version of the SA featuring less logic with fewer processing and pipeline stages yielding a lower clock frequency, would be sufficient for a video analysis system-on-chip.

  4. Echocardiographic parameters and survival in Chagas heart disease with severe systolic dysfunction.

    Science.gov (United States)

    Rassi, Daniela do Carmo; Vieira, Marcelo Luiz Campos; Arruda, Ana Lúcia Martins; Hotta, Viviane Tiemi; Furtado, Rogério Gomes; Rassi, Danilo Teixeira; Rassi, Salvador

    2014-03-01

    Echocardiography provides important information on the cardiac evaluation of patients with heart failure. The identification of echocardiographic parameters in severe Chagas heart disease would help implement treatment and assess prognosis. To correlate echocardiographic parameters with the endpoint cardiovascular mortality in patients with ejection fraction Celular em Cardiopatias) - Chagas heart disease arm. The following parameters were collected: left ventricular systolic and diastolic diameters and volumes; ejection fraction; left atrial diameter; left atrial volume; indexed left atrial volume; systolic pulmonary artery pressure; integral of the aortic flow velocity; myocardial performance index; rate of increase of left ventricular pressure; isovolumic relaxation time; E, A, Em, Am and Sm wave velocities; E wave deceleration time; E/A and E/Em ratios; and mitral regurgitation. In the mean 24.18-month follow-up, 27 patients died. The mean ejection fraction was 26.6 ± 5.34%. In the multivariate analysis, the parameters ejection fraction (HR = 1.114; p = 0.3704), indexed left atrial volume (HR = 1.033; p 70.71 mL/m2 were associated with a significant increase in mortality (log rank p < 0.0001). The indexed left atrial volume was the only independent predictor of mortality in this population of Chagasic patients with severe systolic dysfunction.

  5. Systolic peak detection in acceleration photoplethysmograms measured from emergency responders in tropical conditions.

    Science.gov (United States)

    Elgendi, Mohamed; Norton, Ian; Brearley, Matt; Abbott, Derek; Schuurmans, Dale

    2013-01-01

    Photoplethysmogram (PPG) monitoring is not only essential for critically ill patients in hospitals or at home, but also for those undergoing exercise testing. However, processing PPG signals measured after exercise is challenging, especially if the environment is hot and humid. In this paper, we propose a novel algorithm that can detect systolic peaks under challenging conditions, as in the case of emergency responders in tropical conditions. Accurate systolic-peak detection is an important first step for the analysis of heart rate variability. Algorithms based on local maxima-minima, first-derivative, and slope sum are evaluated, and a new algorithm is introduced to improve the detection rate. With 40 healthy subjects, the new algorithm demonstrates the highest overall detection accuracy (99.84% sensitivity, 99.89% positive predictivity). Existing algorithms, such as Billauer's, Li's and Zong's, have comparable although lower accuracy. However, the proposed algorithm presents an advantage for real-time applications by avoiding human intervention in threshold determination. For best performance, we show that a combination of two event-related moving averages with an offset threshold has an advantage in detecting systolic peaks, even in heat-stressed PPG signals.

  6. Significance of White-Coat Hypertension in Older Persons With Isolated Systolic Hypertension

    Science.gov (United States)

    Franklin, Stanley S.; Thijs, Lutgarde; Hansen, Tine W.; Li, Yan; Boggia, José; Kikuya, Masahiro; Björklund-Bodegård, Kristina; Ohkubo, Takayoshi; Jeppesen, Jørgen; Torp-Pedersen, Christian; Dolan, Eamon; Kuznetsova, Tatiana; Stolarz-Skrzypek, Katarzyna; Tikhonoff, Valérie; Malyutina, Sofia; Casiglia, Edoardo; Nikitin, Yuri; Lind, Lars; Sandoya, Edgardo; Kawecka-Jaszcz, Kalina; Imai, Yutaka; Wang, Jiguang; Ibsen, Hans; O’Brien, Eoin; Staessen, Jan A.

    2013-01-01

    The significance of white-coat hypertension in older persons with isolated systolic hypertension remains poorly understood. We analyzed subjects from the population-based 11-country International Database on Ambulatory Blood Pressure Monitoring in Relation to Cardiovascular Outcomes database who had daytime ambulatory blood pressure (BP; ABP) and conventional BP (CBP) measurements. After excluding persons with diastolic hypertension by CBP (≥90 mm Hg) or by daytime ABP (≥85 mm Hg), a history of cardiovascular disease, and persons hypertension. During a median follow-up of 10.6 years, there was a total of 655 fatal and nonfatal cardiovascular events. The analyses were stratified by treatment status. In untreated subjects, those with white-coat hypertension (CBP ≥140/hypertension, the cardiovascular risk was similar in elevated conventional and normal daytime systolic BP as compared with those with normal conventional and normal daytime BPs (adjusted hazard rate: 1.10 [95% CI: 0.79–1.53]; P=0.57). However, both treated isolated systolic hypertension subjects with white-coat hypertension (adjusted hazard rate: 2.00; [95% CI: 1.43–2.79]; Phypertension who have their ABP normalized on antihypertensive therapy but with residual white-coat effect by CBP measurement have an entity that we have termed, “treated normalized hypertension.” Therefore, one should be cautious in applying the term “white-coat hypertension” to persons receiving antihypertensive treatment. PMID:22252396

  7. "A Tale of Two Planes": Deep Versus Superficial Serratus Plane Block for Postmastectomy Pain Syndrome.

    Science.gov (United States)

    Piracha, Mohammad M; Thorp, Stephen L; Puttanniah, Vinay; Gulati, Amitabh

    Postmastectomy pain syndrome (PMPS) is a significant burden for breast cancer survivors. Although multiple therapies have been described, an evolving field of serratus anterior plane blocks has been described in this population. We describe the addition of the deep serratus anterior plane block (DSPB) for PMPS. Four patients with history of PMPS underwent DSPB for anterior chest wall pain. A retrospective review of these patients' outcomes was obtained through postprocedure interviews. Three of the patients previously had a superficial serratus anterior plane block, which was not as efficacious as the DSPB. The fourth patient had a superficial serratus anterior plane that was difficult to separate with hydrodissection but had improved pain control with a DSPB. We illustrate 4 patients who have benefitted from a DSPB and describe indications that this block may be more efficacious than a superficial serratus plane block. Further study is recommended to understand the intercostal nerve branches within the lateral and anterior muscular chest wall planes.

  8. Spectral analyses of systolic blood pressure and heart rate variability and their association with cognitive performance in elderly hypertensive subjects.

    Science.gov (United States)

    Santos, W B; Matoso, J M D; Maltez, M; Gonçalves, T; Casanova, M; Moreira, I F H; Lourenço, R A; Monteiro, W D; Farinatti, P T V; Soares, P P; Oigman, W; Neves, M F T; Correia, M L G

    2015-08-01

    Systolic hypertension is associated with cognitive decline in the elderly. Altered blood pressure (BP) variability is a possible mechanism of reduced cognitive performance in elderly hypertensives. We hypothesized that altered beat-to-beat systolic BP variability is associated with reduced global cognitive performance in elderly hypertensive subjects. In exploratory analyses, we also studied the correlation between diverse discrete cognitive domains and indices of systolic BP and heart rate variability. Disproving our initial hypothesis, we have shown that hypertension and low education, but not indices of systolic BP and heart rate variability, were independent predictors of lower global cognitive performance. However, exploratory analyses showed that the systolic BP variability in semi-upright position was an independent predictor of matrix reasoning (B = 0.08 ± .03, P-value = 0.005), whereas heart rate variability in semi-upright position was an independent predictor of the executive function score (B = -6.36 ± 2.55, P-value = 0.02). We conclude that myogenic vascular and sympathetic modulation of systolic BP do not contribute to reduced global cognitive performance in treated hypertensive subjects. Nevertheless, our results suggest that both systolic BP and heart rate variability might be associated with modulation of frontal lobe cognitive domains, such as executive function and matrix reasoning.

  9. Affine planes, ternary rings, and examples of non-Desarguesian planes

    OpenAIRE

    Ivanov, Nikolai V.

    2016-01-01

    The paper is devoted to a detailed self-contained exposition of a part of the theory of affine planes leading to a construction of affine (or, equivalently, projective) planes not satisfying the Desarques axiom. It is intended to complement the introductory expositions of the theory of affine and projective planes. A novelty of our exposition is a new notation for the ternary operation in a ternary ring, much more suggestive than the standard one.

  10. Recruitment strategies and challenges in a large intervention trial: Systolic Blood Pressure Intervention Trial.

    Science.gov (United States)

    Ramsey, Thomas M; Snyder, Joni K; Lovato, Laura C; Roumie, Christianne L; Glasser, Steven P; Cosgrove, Nora M; Olney, Christine M; Tang, Rocky H; Johnson, Karen C; Still, Carolyn H; Gren, Lisa H; Childs, Jeffery C; Crago, Osa L; Summerson, John H; Walsh, Sandy M; Perdue, Letitia H; Bankowski, Denise M; Goff, David C

    2016-06-01

    The Systolic Blood Pressure Intervention Trial is a multicenter, randomized clinical trial of 9361 participants with hypertension who are ≥50 years old. The trial is designed to evaluate the effect of intensive systolic blood pressure control (systolic blood pressure goal recruitment strategies and lessons learned during recruitment of the Systolic Blood Pressure Intervention Trial cohort and five targeted participant subgroups: pre-existing cardiovascular disease, pre-existing chronic kidney disease, age ≥75 years, women, and minorities. In collaboration with the National Institutes of Health Project Office and Systolic Blood Pressure Intervention Trial Coordinating Center, five Clinical Center Networks oversaw clinical site selection, recruitment, and trial activities. Recruitment began on 8 November 2010 and ended on 15 March 2013 (about 28 months). Various recruitment strategies were used, including mass mailing, brochures, referrals from healthcare providers or friends, posters, newspaper ads, radio ads, and electronic medical record searches. Recruitment was scheduled to last 24 months to enroll a target of 9250 participants; in just over 28 months, the trial enrolled 9361 participants. The trial screened 14,692 volunteers, with 33% of initial screens originating from the use of mass mailing lists. Screening results show that participants also responded to recruitment efforts through referral by Systolic Blood Pressure Intervention Trial staff, healthcare providers, or friends (45%); brochures or posters placed in clinic waiting areas (15%); and television, radio, newspaper, Internet ads, or toll-free numbers (8%). The overall recruitment yield (number randomized/number screened) was 64% (9361 randomized/14,692 screened), 77% for those with cardiovascular disease, 79% for those with chronic kidney disease, 70% for those aged ≥75 years, 55% for women, and 61% for minorities. As recruitment was observed to lag behind expectations, additional

  11. Aircraft vibration and other factors related to high systolic blood pressure in Indonesian Air Force pilots

    Directory of Open Access Journals (Sweden)

    Minarma Siagian

    2013-05-01

    Full Text Available AbstrakLatar belakang: Penerbangan dapat berdampak pada sistem kardiovaskular manusia. Penerbang terpajan antara lain pada bising dan vibrasi pesawat. Penelitian bertujuan untuk mengetahui pengaruh beberapa faktor penerbangan pada tekanan darah sistolik.Metode: Penelitian nested case-control dilakukan pada penerbang Angkatan Udara Republik Indonesia yang melakukan pemeriksaan fisik tahunan di Lembaga Kesehatan Penerbangan dan Ruang Angkasa (LAKESPRA Saryanto tahun 2003–2008. Data yang diperoleh dari rekam medik berupa umur, jumlah jam terbang, jenis pesawat, kadar glukosa puasa dan kadar kholesterol darah, lingkaran pinggang, tinggi dan berat badan, tinggi badan, serta tekanan darah.Hasil: Dari 336 penerbang, terdapat 16 penerbanga dengan tekanan sistolik ³ 140 mmHg. Penerbang dengan rata-rata jam penerbangan 300-622 jam per tahun dibandingkan dengan 29-299 jam per tahun mempunyai risiko peningkatan tekanan darah sistolik tinggi sebesarf 5 kali [rasio odds suaian (ORa = 5,05, 95% interval kepercayaan (CI = 0,88 -23,30, P = 0,070]. Menurut jam terbang total, mereka yang memiliki 1.401-1,1125 jam dibandingkan 147-1.400 jam berisiko 3,6 kali mengalami tekanan darah sistolik tinggi (ORa = 3,58, 95% CI = 1,24-10,38. Selain itu, mereka dengan denyut nadi istirahat tinggi dibandingkan dengan denyut nadi normal istirahat memiliki 2,4 kali mengalami tekanan darah sistolik tinggi (ORa = 2,37, CI = 0,74-7,50 95, P = 0,147].Kesimpulan: Vibrasi pesawat terbang tinggi, rata-rata jam terbang per tahun tinggi, dan frekuensi nadi istirahat yang tinggi meningkatkan risiko tekanan sistolik tinggi.Kata kunci:tekanan darah sistolik, vibrasi pesawat terbang, frekuensi nadi istirahat, pilotAbstractBackground:Flight may affect the human cardiovascular system. Pilots are exposed among others to aircraft noise and vibration. This study aimed to investigate the effects of aircraft flight on systolic blood pressure.Methods:A nested case-control study was conducted on

  12. Meal sequence and glucose excursion, gastric emptying and incretin secretion in type 2 diabetes: a randomised, controlled crossover, exploratory trial.

    Science.gov (United States)

    Kuwata, Hitoshi; Iwasaki, Masahiro; Shimizu, Shinobu; Minami, Kohtaro; Maeda, Haruyo; Seino, Susumu; Nakada, Koji; Nosaka, Chihiro; Murotani, Kenta; Kurose, Takeshi; Seino, Yutaka; Yabe, Daisuke

    2016-03-01

    Investigation of dietary therapy for diabetes has focused on meal size and composition; examination of the effects of meal sequence on postprandial glucose management is limited. The effects of fish or meat before rice on postprandial glucose excursion, gastric emptying and incretin secretions were investigated. The experiment was a single centre, randomised controlled crossover, exploratory trial conducted in an outpatient ward of a private hospital in Osaka, Japan. Patients with type 2 diabetes (n = 12) and healthy volunteers (n = 10), with age 30-75 years, HbA1c 9.0% (75 mmol/mol) or less, and BMI 35 kg/m(2) or less, were randomised evenly to two groups by use of stratified randomisation, and subjected to meal sequence tests on three separate mornings; days 1 and 2, rice before fish (RF) or fish before rice (FR) in a crossover fashion; and day 3, meat before rice (MR). Pre- and postprandial levels of glucose, insulin, C-peptide and glucagon as well as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide were evaluated. Gastric emptying rate was determined by (13)C-acetate breath test involving measurement of (13)CO2 in breath samples collected before and after ingestion of rice steamed with (13)C-labelled sodium acetate. Participants, people doing measurements or examinations, and people assessing the outcomes were not blinded to group assignment. FR and MR in comparison with RF ameliorated postprandial glucose excursion (AUC-15-240 min-glucose: type 2 diabetes, FR 2,326.6 ± 114.7 mmol/l × min, MR 2,257.0 ± 82.3 mmol/l × min, RF 2,475.6 ± 87.2 mmol/l × min [p Japan Society for Promotion of Science, Japan Association for Diabetes Education and Care, and Japan Vascular Disease Research Foundation.

  13. Accuracy and Precision of a Plane Wave Vector Flow Imaging Method in the Healthy Carotid Artery

    DEFF Research Database (Denmark)

    Jensen, Jonas; Villagómez Hoyos, Carlos Armando; Traberg, Marie Sand

    2018-01-01

    The objective of the study described here was to investigate the accuracy and precision of a plane wave 2-D vector flow imaging (VFI) method in laminar and complex blood flow conditions in the healthy carotid artery. The approach was to study (i) the accuracy for complex flow by comparing...... of laminar flow in vivo. The precision in vivo was calculated as the mean standard deviation (SD) of estimates aligned to the heart cycle and was highest in the center of the common carotid artery (SD = 3.6% for velocity magnitudes and 4.5° for angles) and lowest in the external branch and for vortices (SD...... the velocity field from a computational fluid dynamics (CFD) simulation to VFI estimates obtained from the scan of an anthropomorphic flow phantom and from an in vivo scan; (ii) the accuracy for laminar unidirectional flow in vivo by comparing peak systolic velocities from VFI with magnetic resonance...

  14. Deflection of electron beams by ground planes

    International Nuclear Information System (INIS)

    Fernsler, R.F.; Lampe, M.

    1991-01-01

    Analytic methods are used to determine the effect of a nearby ground plane on the trajectory of a relativistic electron beam passing through dense gas. The beam is shown to respond to the ground plane in one of two distinct modes, determined by beam current and energy. Low-power beams deflect from the ground plane and tear longitudinally. High-power beams do not deflect or tear but tilt, i.e., the beam axis is no longer parallel to the direction of propagation. This conclusion is reached by computing the net beam force as a superposition of the ''bare'' ground-plane forces, the shielding forces from the beam-generated plasma, the body coupling forces induced by beam tilt, and the force that arises as the beam separates from the plasma. Effects from electromagnetic retardation and ground resistivity are shown to be negligible in typical cases of interest, and the interaction between ground planes and other external forces is discussed as well

  15. The horizontal plane appearances of scoliosis

    DEFF Research Database (Denmark)

    Illés, Tamás S.; Burkus, Máté; Somoskeőy, Szabolcs

    2017-01-01

    Purpose: A posterior-anterior vertebral vector is proposed to facilitate visualization and understanding of scoliosis. The aim of this study was to highlight the interest of using vertebral vectors, especially in the horizontal plane, in clinical practice. Methods: We used an EOS two-/three-dimen......Purpose: A posterior-anterior vertebral vector is proposed to facilitate visualization and understanding of scoliosis. The aim of this study was to highlight the interest of using vertebral vectors, especially in the horizontal plane, in clinical practice. Methods: We used an EOS two...... cases of a normal spine and a thoracic scoliosis are presented. Results: For a normal spine, vector projections in the transverse plane are aligned with the posterior-anterior anatomical axis. For a scoliotic spine, vector projections in the horizontal plane provide information on the lateral...... decompensation of the spine and the lateral displacement of vertebrae. In the horizontal plane view, vertebral rotation and projections of the sagittal curves can also be analyzed simultaneously. Conclusions: The use of posterior-anterior vertebral vector facilitates the understanding of the 3D nature...

  16. A Viewpoint on the Quantity "Plane Angle"

    Science.gov (United States)

    Eder, W. E.

    1982-01-01

    Properties of the quantity "plane angle" are explored under the hypothesis that it is a dimensional quantity. The exploration proceeds especially with respect to the physical concept, its mathematical treatment, vector concepts, measurement theory, units of related quantities, engineering pragmatism, and SI. An attempt is made to bring these different relations into a rational, logical and consistent framework, and thus to justify the hypothesis. Various types of vectorial quantities are recognized, and their properties described with an outline of the necessary algebraic manipulations. The concept of plane angle is amplified, and its interdependence with the circular arc is explored. The resulting units of plane angle form a class of similar scales of measurement. Consequences of the confirmed hypothesis are developed for mathematical expressions involving trigonometric functions, rotational volumes and areas, mathematical limits, differentiation and series expansion. Consequences for mechanical rotational quantities are developed, with proposals for revisions to a number of expressions for derived units within SI. A revised definition for the quantity "plane angle" is stated to take account of the developed insights. There is a clear need to reconsider the status of plane angle and some other quantities within the international framework of SI.

  17. Computed tomography of peripancreatic fat planes

    International Nuclear Information System (INIS)

    Wittich, G.R.; Van Sonnenberg, E.; Willson, S.A.; Tobin, R.S.; Cubberley, D.A.; Marx, M.Q.

    1987-01-01

    Obliteration of peripancreatic fat planes usually is considered an indicator of peripancreatic tumour infiltration in the presence of a malignant mass, or of inflammation of peripancreatic tissues in patients with pancreatitis. However, absence of peripancreatic fat planes also may be found in patients without evidence of pancreatic disease. Hence, CT scans of 125 patients without clinical or computed tomographic evidence of pancreatic disease were evaluated to assess normal variations in the anatomy of the pancreas and its relation to surrounding vessels and bowel loops. The fat plane separating the superior mesenteric artery from the pancreas was preserved in 100% of patients. Conversely, fat planes between the pancreas and the superior mesenteric vein, inferior vena cava, and adjacent bowel loops were partially or totally obliterated in 13% to 50% of patients. It is concluded that the absence of fat around the superior mesenteric artery is highly suggestive of pathologic changes of the pancreas, while the lack of fat planes between the pancreas and other splanchnic vessels or bowel loops frequently is normal, and therefore, is an unreliable sign of pancreatic disease. The applications of these findings to the assessment of tumour resectability by CT, and to CT scanning techniques, are discussed. (orig.)

  18. On the theory of twinning plane superconductivity

    International Nuclear Information System (INIS)

    Mishonov, T.M.

    1988-01-01

    The thermodynamic potential of the superconducting layer in the twinning plane (TP) vicinity for the type I superconductors is found. The corrections to the surface tension in powers of the Ginsburg-Landau parameter κ are obtained. The corresponding states law for the supercooling field for the type I twinning plane superconductivity (TPS) is obtained, as well as the critical field law for the type II TPS. A review of experimental and theoretical works on TPS and some similar systems is given. The conditions for the Berezinski-Kosterlitz-Thouless transition for the proximity effect are discussed, as well as the possible mechanisms for the conducting phase transition TPS in Nb and the pinning forces close to the twinning plane. The obtained order parameter distribution can be used for description of the superlattices from normal and superconducting metals as well. 6 figs., 44 refs

  19. Plane wave limits and T-duality

    International Nuclear Information System (INIS)

    Guven, R.

    2000-04-01

    The Penrose limit is generalized to show that, any leading order solution of the low-energy field equations in any one of the five string theories has a plane wave solution as a limit. This limiting procedure takes into account all the massless fields that may arise and commutes with the T-duality so that any dual solution has again a plane wave limit. The scaling rules used in the limit are unique and stem from the scaling property of the D = 11 supergravity action. Although the leading order dual solutions need not be exact or supersymmetric, their plane wave limits always preserve some portion of the Poincare supersymmetry and solve the relevant field equations in all powers of the string tension parameter. Further properties of the limiting procedure are discussed. (author)

  20. Evaluation of the qualification of SPERT [Special Power Excursion Reactor Test] fuel for use in non-power reactors

    International Nuclear Information System (INIS)

    1987-08-01

    This report summarizes the US Nuclear Regulatory Commission staff's evaluation of the qualification of the stainless-steel-clad uranium/oxide (UO 2 ) fuel pins for use in non-power reactors. The fuel pins were originally procured in the 1960's as part of the Special Power Excursion Reactor Test (SPERT) program. Argonne National Laboratory (ANL) examined 600 SPERT fuel pins to verify that the pins were produced according to specification and to assess their present condition. The pins were visually inspected under 6X magnification and by X-radiographic, destructive, and metallographic examinations. Spectrographic and chemical analyses were performed on the UO 2 fuel. The results of the qualification examinations indicated that the SPERT fuel pins meet the requirements of Phillips Specification No. F-1-SPT and have suffered no physical damage since fabrication. Therefore, the qualification results give reasonable assurance that the SPERT fuel rods are suitable for use in non-power reactors provided that the effects of thin-wall defects in the region of the upper end cap and low-density fuel pellets are evaluated for the intended operating conditions. 1 ref., 4 figs., 11 tabs

  1. The ability of modified star excursion balance test to differentiate between women athletes with and without chronic ankle instability

    Directory of Open Access Journals (Sweden)

    Asma Razeghi

    2016-05-01

    Full Text Available The Star Excursion Balance Test (SEBT is one functional clinical test that widely used to assess dynamic balance in patients with ankle injuries. Since the ability of this test to detect impairments between athletes with and without chronic ankle instability(CAI is not clear, the aim of present study was to determine if the modified SEBT could detect reach deficits in patients with unilateral CAI. A convenience sample of thirty elite and sub elite women athletes were selected and assigned into two groups: CAI group (Mean ± SD: age: 25±3.5 years; height: 1.68±0.09 m; weight: 62.7±7.3kg, and healthy controls (Mean ± SD: age: 26±4.2 years; height: 1.69±0.05 m; weigh t: 62.7±7.3 kg.The dynamic balance test was obtained using modified SEBT from both limbs of each participant. The independent sample t-test was used for both between group and within group inter-limb comparisons. There was no significant difference in any directions of modified SEBT between two groups in both limbs. No significant interlimb differences were also observed within both groups. The modified SEBT may not enough sensitive to differentiate between athletes with and without CAI. Other factors such as ankle range of motion, muscle strength and pain intensity should be considered for better interpretation of the SEBT results.

  2. Oxygen-isotope trends and seawater temperature changes across the Late Cambrian Steptoean positive carbon-isotope excursion (SPICE event)

    Science.gov (United States)

    Elrick, M.; Rieboldt, S.; Saltzman, M.; McKay, R.M.

    2011-01-01

    The globally recognized Late Cambrian Steptoean positive C-isotope excursion (SPICE) is characterized by a 3???-5??? positive ??13C shift spanning SPICE represents a widespread ocean anoxic event leading to enhanced burial/preservation of organic matter (Corg) and pyrite. We analyzed ??18O values of apatitic inarticulate brachiopods from three Upper Cambrian successions across Laurentia to evaluate paleotemperatures during the SPICE. ??18O values range from ~12.5??? to 16.5???. Estimated seawater temperatures associated with the SPICE are unreasonably warm, suggesting that the brachiopod ??18O values were altered during early diagenesis. Despite this, all three localities show similar trends with respect to the SPICE ??13C curve, suggesting that the brachiopod apatite preserves a record of relative ??18O and temperature changes. The trends include relatively high ??18O values at the onset of the SPICE, decreasing and lowest values during the main event, and an increase in values at the end of the event. The higher ??18O values during the global extinction at the onset of the SPICE suggests seawater cooling and supports earlier hypotheses of upwelling of cool waters onto the shallow shelf. Decreasing and low ??18O values coincident with the rising limb of the SPICE support the hypothesis that seawater warming and associated reduced thermohaline circulation rates contributed to decreased dissolved O2 concentrations, which enhanced the preservation/burial of Corg causing the positive ??13C shift. ?? 2011 Geological Society of America.

  3. Geometry and scaling laws of excursion and iso-sets of enstrophy and dissipation in isotropic turbulence

    Science.gov (United States)

    Elsas, José Hugo; Szalay, Alexander S.; Meneveau, Charles

    2018-04-01

    Motivated by interest in the geometry of high intensity events of turbulent flows, we examine the spatial correlation functions of sets where turbulent events are particularly intense. These sets are defined using indicator functions on excursion and iso-value sets. Their geometric scaling properties are analysed by examining possible power-law decay of their radial correlation function. We apply the analysis to enstrophy, dissipation and velocity gradient invariants Q and R and their joint spatial distributions, using data from a direct numerical simulation of isotropic turbulence at Reλ ≈ 430. While no fractal scaling is found in the inertial range using box-counting in the finite Reynolds number flow considered here, power-law scaling in the inertial range is found in the radial correlation functions. Thus, a geometric characterisation in terms of these sets' correlation dimension is possible. Strong dependence on the enstrophy and dissipation threshold is found, consistent with multifractal behaviour. Nevertheless, the lack of scaling of the box-counting analysis precludes direct quantitative comparisons with earlier work based on multifractal formalism. Surprising trends, such as a lower correlation dimension for strong dissipation events compared to strong enstrophy events, are observed and interpreted in terms of spatial coherence of vortices in the flow.

  4. Concurrent and discriminant validity of the Star Excursion Balance Test for military personnel with lateral ankle sprain.

    Science.gov (United States)

    Bastien, Maude; Moffet, Hélène; Bouyer, Laurent; Perron, Marc; Hébert, Luc J; Leblond, Jean

    2014-02-01

    The Star Excursion Balance Test (SEBT) has frequently been used to measure motor control and residual functional deficits at different stages of recovery from lateral ankle sprain (LAS) in various populations. However, the validity of the measure used to characterize performance--the maximal reach distance (MRD) measured by visual estimation--is still unknown. To evaluate the concurrent validity of the MRD in the SEBT estimated visually vs the MRD measured with a 3D motion-capture system and evaluate and compare the discriminant validity of 2 MRD-normalization methods (by height or by lower-limb length) in participants with or without LAS (n = 10 per group). There is a high concurrent validity and a good degree of accuracy between the visual estimation measurement and the MRD gold-standard measurement for both groups and under all conditions. The Cohen d ratios between groups and MANOVA products were higher when computed from MRD data normalized by height. The results support the concurrent validity of visual estimation of the MRD and the use of the SEBT to evaluate motor control. Moreover, normalization of MRD data by height appears to increase the discriminant validity of this test.

  5. Relationship between the modified star excursion balance test and the 4x10 m shuttle run test in children

    Directory of Open Access Journals (Sweden)

    Joaquín Calatayud

    2017-01-01

    Full Text Available Resumen La agilidad y el equilibrio dinámico son habilidades cruciales en la actividad física prepuberal y la participación deportiva, por lo tanto es necesaria la identificación de pruebas eficientes para su evaluación. Evaluar la correlación entre la agilidad y el equilibrio dinámico en niños escolares de primaria. Veintisiete niños y veinte niñas de 10 años participaron voluntariamente en el estudio. El Star Excursion Balance Test (SEBT modificado y el 4x10 m Shuttle Run Test se utilizaron respectivamente para evaluar el equilibrio dinámico y agilidad. Las puntuaciones compuestas del equilibrio dinámico con apoyo diestro mostraron solo entre los niños una moderada correlación significativa (r = -0.51, p < 0.05 con la prueba de agilidad. Sin embargo, entre las niñas se mostró una correlación significativa (r = -0.45, p < 0.05 durante la distancia de alcance posterolateral obtenida en el SEBT. La realización del test completo o de las distancias alcanzadas a nivel posteromedial y posterolateral del SEBT se asocia moderadamente con la agilidad entre los niños, mientras que la distancia posterolateral se asocia con la agilidad entre las niñas.

  6. Bound on largest r ∼< 0.1 from sub-Planckian excursions of inflaton

    International Nuclear Information System (INIS)

    Chatterjee, Arindam; Mazumdar, Anupam

    2015-01-01

    In this paper we will discuss the range of large tensor to scalar ratio, r, obtainable from a sub-Planckian excursion of a single, slow roll driven inflaton field. In order to obtain a large r for such a scenario one has to depart from a monotonic evolution of the slow roll parameters in such a way that one still satisfies all the current constraints of \\texttt(Planck), such as the scalar amplitude, the tilt in the scalar power spectrum, running and running of the tilt close to the pivot scale. Since the slow roll parameters evolve non-monotonically, we will also consider the evolution of the power spectrum on the smallest scales, i.e. at P s (k ∼ 10 16  Mpc −1 )∼< 10 −2 , to make sure that the amplitude does not become too large. All these constraints tend to keep the tensor to scalar ratio, r ∼< 0.1. We scan three different kinds of potential for supersymmetric flat directions and obtain the benchmark points which satisfy all the constraints. We also show that it is possible to go beyond r ∼> 0.1 provided we relax the upper bound on the power spectrum on the smallest scales

  7. Evaluation of Postprandial Glucose Excursion Using a Novel Minimally Invasive Glucose Area-Under-the-Curve Monitoring System

    Directory of Open Access Journals (Sweden)

    Sachi Kuranuki

    2013-01-01

    Full Text Available Objective: To develop a minimally invasive interstitial fluid extraction technology (MIET to monitor postprandial glucose area under the curve (AUC without blood sampling, we evaluated the accuracy of glucose AUC measured by MIET and compared with that by blood sampling after food intake. Methods: Interstitial fluid glucose AUC (IG-AUC following consumption of 6 different types of foods was measured by MIET. MIET consisted of stamping microneedle arrays, placing hydrogel patches on the areas, and calculating IG-AUC based on glucose levels in the hydrogels. Glycemic index (GI was determined using IG-AUC and reference AUC measured by blood sampling. Results: IG-AUC strongly correlated with reference AUC (R = 0.91, and GI determined using IG-AUC showed good correlation with that determined by reference AUC (R = 0.88. Conclusions: IG-AUC obtained by MIET can accurately predict the postprandial glucose excursion without blood sampling. In addition, feasibility of GI measurement by MIET was confirmed.

  8. Topologically protected edge states for out-of-plane and in-plane bulk elastic waves

    Science.gov (United States)

    Huo, Shao-Yong; Chen, Jiu-Jiu; Huang, Hong-Bo

    2018-04-01

    Topological phononic insulators (TPnIs) show promise for application in the manipulation of acoustic waves for the design of low-loss transmission and perfectly integrated communication devices. Since solid phononic crystals exist as a transverse polarization mode and a mixed longitudinal-transverse polarization mode, the realization of topological edge states for both out-of-plane and in-plane bulk elastic waves is desirable to enhance the controllability of the edge waves in solid systems. In this paper, a two-dimensional (2D) solid/solid hexagonal-latticed phononic system that simultaneously supports the topologically protected edge states for out-of-plane and in-plane bulk elastic waves is investigated. Firstly, two pairs of two-fold Dirac cones, respectively corresponding to the out-of-plane and in-plane waves, are obtained at the same frequency by tuning the crystal parameters. Then, a strategy of zone folding is invoked to form double Dirac cones. By shrinking and expanding the steel scatterer, the lattice symmetry is broken, and band inversions induced, giving rise to an intriguing topological phase transition. Finally, the topologically protected edge states for both out-of-plane and in-plane bulk elastic waves, which can be simultaneously located at the frequency range from 1.223 to 1.251 MHz, are numerically observed. Robust pseudospin-dependent elastic edge wave propagation along arbitrary paths is further demonstrated. Our results will significantly broaden its practical application in the engineering field.

  9. Beat-to-beat systolic time-interval measurement from heart sounds and ECG

    International Nuclear Information System (INIS)

    Paiva, R P; Carvalho, P; Couceiro, R; Henriques, J; Antunes, M; Quintal, I; Muehlsteff, J

    2012-01-01

    Systolic time intervals are highly correlated to fundamental cardiac functions. Several studies have shown that these measurements have significant diagnostic and prognostic value in heart failure condition and are adequate for long-term patient follow-up and disease management. In this paper, we investigate the feasibility of using heart sound (HS) to accurately measure the opening and closing moments of the aortic heart valve. These moments are crucial to define the main systolic timings of the heart cycle, i.e. pre-ejection period (PEP) and left ventricular ejection time (LVET). We introduce an algorithm for automatic extraction of PEP and LVET using HS and electrocardiogram. PEP is estimated with a Bayesian approach using the signal's instantaneous amplitude and patient-specific time intervals between atrio-ventricular valve closure and aortic valve opening. As for LVET, since the aortic valve closure corresponds to the start of the S2 HS component, we base LVET estimation on the detection of the S2 onset. A comparative assessment of the main systolic time intervals is performed using synchronous signal acquisitions of the current gold standard in cardiac time-interval measurement, i.e. echocardiography, and HS. The algorithms were evaluated on a healthy population, as well as on a group of subjects with different cardiovascular diseases (CVD). In the healthy group, from a set of 942 heartbeats, the proposed algorithm achieved 7.66 ± 5.92 ms absolute PEP estimation error. For LVET, the absolute estimation error was 11.39 ± 8.98 ms. For the CVD population, 404 beats were used, leading to 11.86 ± 8.30 and 17.51 ± 17.21 ms absolute PEP and LVET errors, respectively. The results achieved in this study suggest that HS can be used to accurately estimate LVET and PEP. (paper)

  10. Systolic reconstruction in patients with low heart rate using coronary dual-source CT angiography

    International Nuclear Information System (INIS)

    Okada, Munemasa; Nakashima, Yoshiteru; Shigemoto, Youko; Matsunaga, Naofumi; Miura, Toshiro; Nao, Tomoko; Sano, Yuichi; Narazaki, Akiko; Kido, Shoji

    2011-01-01

    Objectives: The purpose of our study was to determine the relationship between the predictive factors and systolic reconstruction (SR) as an optimal reconstruction window in patients with low heart rate (LHR; less than 65 bpm). Methods: 391 patients (262 male and 129 female, mean age; 67.1 ± 10.1 years of age) underwent coronary CTA without the additional administration of a beta-blocker. Affecting factors for SR were analyzed in age, gender, body weight (BW), diabetes mellitus (DM), coronary arterial disease (CAD), ejection fraction (EF), systolic and diastolic body pressure (BP) and heart rate variability (HRV) during coronary CTA. Results: In 29 (7.4%) of the 391 patients, SR was needed, but there was no apparent characteristic difference between the systolic and diastolic reconstruction groups in terms of gender, age, BW, DM, CAD and EF. In a multivariate analysis, the co-existence of DM [P < 0.05; OR, 0.27; 95% CI, 0.092-0.80], diastolic BP [P < 0.01; OR, 0.95; 95% CI, 0.92-0.98] and HRV [P < 0.01; OR, 0.98; 95% CI, 0.96-0.99] were found to be the factors for SR. In gender-related analysis, HRV was an important factor regardless of sex, but co-existence of DM affected especially for female and BP for male. Conclusion: Especially in the patients with LHR who had a medication of DM, high HRV or high BP, SR, in addition to DR, was needed to obtain high-quality coronary CTA images.

  11. [Type B natriuretic peptide in the diagnosis of heart failure with preserved systolic function].

    Science.gov (United States)

    Castro, A; Dias, P; Pereira, M; Pimenta, J; Friões, F; Rodrigues, R; Ferreira, A; Bettencourt, P

    2001-11-01

    Heart failure (HF) with preserved left ventricular systolic function (LVSF) is observed in up to 50% patients with HF. There is no consensus on non-invasive diagnosis of this entity. Evaluation of B-type natriuretic peptide (BNP) in the diagnosis of HF with preserved left ventricular systolic function. Prospective study. One hundred and seventy-six consecutive patients with suspected HF were evaluated. Patients were classified as having HF with preserved LVSF, if they had symptoms and signs of HF, an ejection fraction greater than 40% and an abnormal Doppler pattern of the mitral inflow or atrial fibrilation and no other causes for the symptoms. All patients had a 12-lead EKG, chest roentgenogram, simple spirometry, M-mode and 2D echocardiogram with pulsed Doppler study of transmitral inflow and determination of plasma BNP levels. Of the 176 patients, 65 had ejection fraction greater than 40%. Of these patients 46 were classified as having HF with preserved LVSF and 19 as not having HF. Patients with HF and preserved LVSF were older, had a higher systolic blood pressure (SBP), less pathologic Q waves on ECG and higher left ventricular ejection fraction and plasma BNP than patients without HF. Multivariate analysis revealed that BNP and SBP were independently associated with the diagnosis of HF. The accuracy of BNP in the diagnosis of HF with preserved LVSF evaluated by the area under the receiver operating characteristic curve was 0.94. These results suggest that the measurement of BNP levels can help clinicians in the diagnosis of HF with preserved LVSF. Whether BNP levels might be used in clinical practice as a test for the diagnosis of HF with preserved LVSF is a question that merits further studies.

  12. Systolic reconstruction in patients with low heart rate using coronary dual-source CT angiography

    Energy Technology Data Exchange (ETDEWEB)

    Okada, Munemasa, E-mail: radokada@yamaguchi-u.ac.jp [Department of Radiology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minamikogushi, Ube, Yamaguchi 755-8505 (Japan); Nakashima, Yoshiteru; Shigemoto, Youko; Matsunaga, Naofumi [Department of Radiology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minamikogushi, Ube, Yamaguchi 755-8505 (Japan); Miura, Toshiro; Nao, Tomoko [Department of Cardiology, Yamaguchi University Graduate School of Medicine (Japan); Sano, Yuichi; Narazaki, Akiko [Department of Radiology, Yamaguchi University Hospital (Japan); Kido, Shoji [Computer-aided Diagnosis and Biomedical Imaging Research Biomedical Engineering, Applied Medical Engineering Science Graduate School of Medicine, Yamaguchi University (Japan)

    2011-11-15

    Objectives: The purpose of our study was to determine the relationship between the predictive factors and systolic reconstruction (SR) as an optimal reconstruction window in patients with low heart rate (LHR; less than 65 bpm). Methods: 391 patients (262 male and 129 female, mean age; 67.1 {+-} 10.1 years of age) underwent coronary CTA without the additional administration of a beta-blocker. Affecting factors for SR were analyzed in age, gender, body weight (BW), diabetes mellitus (DM), coronary arterial disease (CAD), ejection fraction (EF), systolic and diastolic body pressure (BP) and heart rate variability (HRV) during coronary CTA. Results: In 29 (7.4%) of the 391 patients, SR was needed, but there was no apparent characteristic difference between the systolic and diastolic reconstruction groups in terms of gender, age, BW, DM, CAD and EF. In a multivariate analysis, the co-existence of DM [P < 0.05; OR, 0.27; 95% CI, 0.092-0.80], diastolic BP [P < 0.01; OR, 0.95; 95% CI, 0.92-0.98] and HRV [P < 0.01; OR, 0.98; 95% CI, 0.96-0.99] were found to be the factors for SR. In gender-related analysis, HRV was an important factor regardless of sex, but co-existence of DM affected especially for female and BP for male. Conclusion: Especially in the patients with LHR who had a medication of DM, high HRV or high BP, SR, in addition to DR, was needed to obtain high-quality coronary CTA images.

  13. Echocardiographic Parameters and Survival in Chagas Heart Disease with Severe Systolic Dysfunction

    International Nuclear Information System (INIS)

    Rassi, Daniela do Carmo; Vieira, Marcelo Luiz Campos; Arruda, Ana Lúcia Martins; Hotta, Viviane Tiemi; Furtado, Rogério Gomes; Rassi, Danilo Teixeira; Rassi, Salvador

    2014-01-01

    Echocardiography provides important information on the cardiac evaluation of patients with heart failure. The identification of echocardiographic parameters in severe Chagas heart disease would help implement treatment and assess prognosis. To correlate echocardiographic parameters with the endpoint cardiovascular mortality in patients with ejection fraction < 35%. Study with retrospective analysis of pre-specified echocardiographic parameters prospectively collected from 60 patients included in the Multicenter Randomized Trial of Cell Therapy in Patients with Heart Diseases (Estudo Multicêntrico Randomizado de Terapia Celular em Cardiopatias) - Chagas heart disease arm. The following parameters were collected: left ventricular systolic and diastolic diameters and volumes; ejection fraction; left atrial diameter; left atrial volume; indexed left atrial volume; systolic pulmonary artery pressure; integral of the aortic flow velocity; myocardial performance index; rate of increase of left ventricular pressure; isovolumic relaxation time; E, A, Em, Am and Sm wave velocities; E wave deceleration time; E/A and E/Em ratios; and mitral regurgitation. In the mean 24.18-month follow-up, 27 patients died. The mean ejection fraction was 26.6 ± 5.34%. In the multivariate analysis, the parameters ejection fraction (HR = 1.114; p = 0.3704), indexed left atrial volume (HR = 1.033; p < 0.0001) and E/Em ratio (HR = 0.95; p = 0.1261) were excluded. The indexed left atrial volume was an independent predictor in relation to the endpoint, and values > 70.71 mL/m 2 were associated with a significant increase in mortality (log rank p < 0.0001). The indexed left atrial volume was the only independent predictor of mortality in this population of Chagasic patients with severe systolic dysfunction

  14. Cardiac I123-MIBG Correlates Better than Ejection Fraction with Symptoms Severity in Systolic Heart Failure

    Energy Technology Data Exchange (ETDEWEB)

    Miranda, Sandra M.; Moscavitch, Samuel D.; Carestiato, Larissa R. [Programa de Pós-Graduação em Ciências Cardiovasculares, Hospital Universitário Antonio Pedro, Universidade Federal Fluminense, Rio de Janeiro, RJ (Brazil); Felix, Renata M. [Departamento de Medicina Nuclear, Hospital Pró-Cardíaco, Rio de Janeiro, RJ (Brazil); Rodrigues, Ronaldo C.; Messias, Leandro R. [Programa de Pós-Graduação em Ciências Cardiovasculares, Hospital Universitário Antonio Pedro, Universidade Federal Fluminense, Rio de Janeiro, RJ (Brazil); Azevedo, Jader C. [Programa de Pós-Graduação em Ciências Cardiovasculares, Hospital Universitário Antonio Pedro, Universidade Federal Fluminense, Rio de Janeiro, RJ (Brazil); Departamento de Medicina Nuclear, Hospital Pró-Cardíaco, Rio de Janeiro, RJ (Brazil); Nóbrega, Antonio Cláudio L.; Mesquita, Evandro Tinoco [Programa de Pós-Graduação em Ciências Cardiovasculares, Hospital Universitário Antonio Pedro, Universidade Federal Fluminense, Rio de Janeiro, RJ (Brazil); Mesquita, Claudio Tinoco, E-mail: ctinocom@cardiol.br [Programa de Pós-Graduação em Ciências Cardiovasculares, Hospital Universitário Antonio Pedro, Universidade Federal Fluminense, Rio de Janeiro, RJ (Brazil); Departamento de Medicina Nuclear, Hospital Pró-Cardíaco, Rio de Janeiro, RJ (Brazil)

    2013-07-15

    The association of autonomic activation, left ventricular ejection fraction (LVEF) and heart failure functional class is poorly understood. Our aim was to correlate symptom severity with cardiac sympathetic activity, through iodine-123-metaiodobenzylguanidine ({sup 123}I-MIBG) scintigraphy and with LVEF in systolic heart failure (HF) patients without previous beta-blocker treatment. Thirty-one patients with systolic HF, class I to IV of the New York Heart Association (NYHA), without previous beta-blocker treatment, were enrolled and submitted to {sup 123}I-MIBG scintigraphy and to radionuclide ventriculography for LVEF determination. The early and delayed heart/mediastinum (H/M) ratio and the washout rate (WR) were performed. According with symptom severity, patients were divided into group A, 13 patients in NYHA class I/II, and group B, 18 patients in NYHA class III/IV. Compared with group B patients, group A had a significantly higher LVEF (25% ± 12% in group B vs. 32% ± 7% in group A, p = 0.04). Group B early and delayed H/M ratios were lower than group A ratios (early H/M 1.49 ± 0.15 vs. 1.64 ± 0.14, p = 0.02; delayed H/M 1.39 ± 0.13 vs. 1.58 ± 0.16, p = 0.001, respectively). WR was significantly higher in group B (36% ± 17% vs. 30% ± 12%, p= 0.04). The variable that showed the best correlation with NYHA class was the delayed H/M ratio (r= -0.585; p=0.001), adjusted for age and sex. This study showed that cardiac {sup 123}I-MIBG correlates better than ejection fraction with symptom severity in systolic heart failure patients without previous beta-blocker treatment.

  15. Urinary albumin excretion is associated with nocturnal systolic blood pressure in resistant hypertensives.

    Science.gov (United States)

    Oliveras, Anna; Armario, Pedro; Martell-Clarós, Nieves; Ruilope, Luis M; de la Sierra, Alejandro

    2011-03-01

    Microalbuminuria is a known marker of subclinical organ damage. Its prevalence is higher in patients with resistant hypertension than in subjects with blood pressure at goal. On the other hand, some patients with apparently well-controlled hypertension still have microalbuminuria. The current study aimed to determine the relationship between microalbuminuria and both office and 24-hour ambulatory blood pressure. A cohort of 356 patients (mean age 64 ± 11 years; 40.2% females) with resistant hypertension (blood pressure ≥ 140 and/or 90 mm Hg despite treatment with ≥ 3 drugs, diuretic included) were selected from Spanish hypertension units. Patients with estimated glomerular filtration rate <30 mL/min/1.73 m(2) were excluded. All patients underwent clinical and demographic evaluation, complete laboratory analyses, and good technical-quality 24-hour ambulatory blood pressure monitoring. Urinary albumin/creatinine ratio was averaged from 3 first-morning void urine samples. Microalbuminuria (urinary albumin/creatinine ratio ≥ 2.5 mg/mmol in males or ≥ 3.5 mg/mmol in females) was detected in 46.6%, and impaired renal function (estimated glomerular filtration rate <60 mL/min/1.73 m(2)) was detected in 26.8%. Bivariate analyses showed significant associations of microalbuminuria with older age, reduced estimated glomerular filtration rate, increased nighttime systolic blood pressure, and elevated daytime, nighttime, and 24-hour diastolic blood pressure. In a logistic regression analysis, after age and sex adjustment, elevated nighttime systolic blood pressure (multivariate odds ratio, 1.014 [95% CI, 1.001 to 1.026]; P=0.029) and reduced estimated glomerular filtration rate (multivariate odds ratio, 2.79 [95% CI, 1.57 to 4.96]; P=0.0005) were independently associated with the presence of microalbuminuria. We conclude that microalbuminuria is better associated with increased nighttime systolic blood pressure than with any other office and 24-hour ambulatory blood

  16. Echocardiographic Parameters and Survival in Chagas Heart Disease with Severe Systolic Dysfunction

    Energy Technology Data Exchange (ETDEWEB)

    Rassi, Daniela do Carmo, E-mail: dani.rassi@hotmail.com [Faculdade de Medicina e Hospital das Clínicas da Universidade Federal de Goiás (UFG), Goiânia, GO (Brazil); Vieira, Marcelo Luiz Campos [Instituto do Coração da Faculdade de Medicina da Universidade de São Paulo (USP), São Paulo, SP (Brazil); Arruda, Ana Lúcia Martins [Instituto de Radiologia da Faculdade de Medicina da Universidade de São Paulo (USP), São Paulo, SP (Brazil); Hotta, Viviane Tiemi [Instituto do Coração da Faculdade de Medicina da Universidade de São Paulo (USP), São Paulo, SP (Brazil); Furtado, Rogério Gomes; Rassi, Danilo Teixeira; Rassi, Salvador [Faculdade de Medicina e Hospital das Clínicas da Universidade Federal de Goiás (UFG), Goiânia, GO (Brazil)

    2014-03-15

    Echocardiography provides important information on the cardiac evaluation of patients with heart failure. The identification of echocardiographic parameters in severe Chagas heart disease would help implement treatment and assess prognosis. To correlate echocardiographic parameters with the endpoint cardiovascular mortality in patients with ejection fraction < 35%. Study with retrospective analysis of pre-specified echocardiographic parameters prospectively collected from 60 patients included in the Multicenter Randomized Trial of Cell Therapy in Patients with Heart Diseases (Estudo Multicêntrico Randomizado de Terapia Celular em Cardiopatias) - Chagas heart disease arm. The following parameters were collected: left ventricular systolic and diastolic diameters and volumes; ejection fraction; left atrial diameter; left atrial volume; indexed left atrial volume; systolic pulmonary artery pressure; integral of the aortic flow velocity; myocardial performance index; rate of increase of left ventricular pressure; isovolumic relaxation time; E, A, Em, Am and Sm wave velocities; E wave deceleration time; E/A and E/Em ratios; and mitral regurgitation. In the mean 24.18-month follow-up, 27 patients died. The mean ejection fraction was 26.6 ± 5.34%. In the multivariate analysis, the parameters ejection fraction (HR = 1.114; p = 0.3704), indexed left atrial volume (HR = 1.033; p < 0.0001) and E/Em ratio (HR = 0.95; p = 0.1261) were excluded. The indexed left atrial volume was an independent predictor in relation to the endpoint, and values > 70.71 mL/m{sup 2} were associated with a significant increase in mortality (log rank p < 0.0001). The indexed left atrial volume was the only independent predictor of mortality in this population of Chagasic patients with severe systolic dysfunction.

  17. Acute Effects of Positive Airway Pressure on Functional Mitral Regurgitation in Patients with Systolic Heart Failure

    Directory of Open Access Journals (Sweden)

    Takao Kato

    2017-11-01

    Full Text Available Background: Acute effects of positive airway pressure (PAP [including continuous PAP (CPAP and adaptive servo-ventilation, an advanced form of bi-level PAP] on functional mitral regurgitation (fMR in patients with heart failure (HF with left ventricular (LV systolic dysfunction remain unclear. Thus, whether PAP therapy reduces fMR in such patients with HF was investigated.Methods and Results: Twenty patients with HF and LV systolic dysfunction defined as LV ejection fraction (LVEF <50% (14 men; mean LVEF, 35.0 ± 11.5% with fMR underwent echocardiography during 10-min CPAP (4 and 8 cm H2O and adaptive servo-ventilation. For fMR assessment, MR jet area fraction, defined as the ratio of MR jet on color Doppler to the left atrial area, was measured. The forward stroke volume (SV index (fSVI was calculated from the time-velocity integral, cross-sectional area of the aortic annulus, and body surface area. fMR significantly reduced on CPAP at 8 cm H2O (0.30 ± 0.12 and adaptive servo-ventilation (0.29 ± 0.12, compared with the baseline phase (0.37 ± 0.12 and CPAP at 4 cm H2O (0.34 ± 0.12 (P < 0.001. The fSVI did not change in any of the PAP sessions (P = 0.888. However, significant differences in fSVI responses to PAP were found between sexes (P for interaction, 0.006, with a significant reduction in fSVI in women (P = 0.041 and between patients with baseline fSVI ≥ and < the median value (27.8 ml/m2, P for interaction, 0.018, with a significant fSVI reduction in patients with high baseline fSVI (P = 0.028. In addition, significant differences were found in fSVI responses to PAP between patients with LV end-systolic volume (LVESV index ≥ and < the median value (62.0 ml/m2, P for interaction, 0.034, with a significant fSVI increase in patients with a high LVESV index (P = 0.023.Conclusion: In patients with HF, LV systolic dysfunction, and fMR, PAP can alleviate fMR without any overall changes in forward SV. However, MR alleviation due to PAP

  18. Central aortic systolic blood pressure can predict prolonged QTc duration better than brachial artery systolic blood pressure in rural community residents.

    Science.gov (United States)

    Huang, Yuqing; Tang, Songtao; Chen, Ji-Yan; Huang, Cheng; Li, Jie; Cai, An-Ping; Feng, Yingqing

    2018-01-01

    Previous studies have suggested that prolonged electrocardiogram QTc duration was independent risk factor for both increased cardiovascular and all-cause mortality, but there was no dating about the relationship between central aortic systolic blood pressure (CASP) and QTc duration. The aim of this study was to analyze the relationship between CASP and QTc duration, and assess whether CASP can predict prolonged QTc duration more than BSBP. A total of 500 patients were enrolled in this study, central and brachial aortic blood pressure and electrocardiogram QTc duration were measured. Pearson correlation was assessed for determining the associations of QTc duration with clinical conditions. Multivariate logistic regression analyses were performed to determine the independent predictor of prolonged QTc duration. Receiver operating characteristic (ROC) curve was used to evaluate the utility of blood pressure for prolonged QTc duration. We found QTc durations were significantly positive with CASP (r = 0.308, p AUC: 0.771 vs. 0.646, p < 0.001) BSBP. Our results suggested that the non-invasive CASP is independently correlated with QTc duration, and CASP can predict prolonged QTc duration more than BSBP.

  19. A new dynamic myocardial phantom for evaluation of SPECT and PET quantitation in systolic and diastolic conditions

    International Nuclear Information System (INIS)

    Dreuille, O. de; Bendriem, B.; Riddell, C.

    1996-01-01

    We present a new dynamic myocardial phantom designed to evaluate SPECT and PET imaging in systolic and diastolic conditions. The phantom includes a thoracic attenuating media and the myocardial wall thickness varying during the scan can be performed. In this study the phantom was used with three different wall thickness characteristic of a systolic, end-diastolic and pathologic end-diastolic condition. The myocardium was filled with 99m Tc, 18 F and Gd and imaged by SPECT, PET and MRI. SPECT attenuation correction was performed using a modified PET transmission. A bull's eyes image was obtained for all data and wall ROI were then drawn for analysis. Using MRI as a reference, error from PET, SPECT and attenuation corrected SPECT were calculated. Systolic PET performances agree with MRI. Quantitation loss due to wall thickness reduction compared to the systole. Attenuation correction in SPECT leads to significant decrease of the error both in systole (from 29% to 14%) and diastole (35% to 22%). This is particularly sensitive for septum and inferior walls. SPECT residual errors (14% in systole and 22% in pathologic end-diastole) are likely caused by scatter, noise and depth dependent resolution effect. The results obtained with this dynamical phantom demonstrate the quantitation improvement achieved in SPECT with attenuation correction and also reinforce the need for variable resolution correction in addition to attenuation correction

  20. Prevalence and implications of a difference in systolic blood pressure between one arm and the other in vascular surgical patients.

    Science.gov (United States)

    Durrand, J W; Batterham, A M; O'Neill, B R; Danjoux, G R

    2013-12-01

    Inter-arm differences in blood pressure may confound haemodynamic management in vascular surgery. We evaluated 898 patients in the vascular pre-assessment clinic to determine the prevalence of inter-arm differences in systolic and mean arterial pressure, quantify the consequent risk of clinical error in siting monitoring peri-operatively and evaluate systolic inter-arm difference as a predictor of all-cause mortality (median follow-up 49 months). The prevalence of a systolic inter-arm difference ≥ 15 mmHg was 26% (95% CI 23-29%). The prevalence of an inter-arm mean arterial pressure difference ≥ 10 mmHg was 26% (95% CI 23-29%) and 11% (95% CI 9-13%) for a difference ≥ 15 mmHg. Monitoring could be erroneously sited in an arm reading lower for systolic pressure once in every seven to nine patients. The hazard ratio for a systolic inter-arm difference ≥ 15 mmHg vs arm blood pressure differences are common in this population, with a high potential for monitoring errors. Systolic inter-arm difference was not associated with medium-term mortality. [Correction added on 17 October 2013, after first online publication: In the Summary the sentence beginning 'We evaluated 898 patients' was corrected from (median (IQR [range]) follow-up 49 months) to read (median follow up 49 months)]. © 2013 The Association of Anaesthetists of Great Britain and Ireland.

  1. Study of the thermal and hydraulic phenomena occurring during power excursion on a heated test section; Etude des phenomenes thermiques et hydrauliques accompagnant une excursion rapide de puissance sur un canal chauffant

    Energy Technology Data Exchange (ETDEWEB)

    Nyer, M [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1969-07-01

    The thermal and hydrodynamic phenomena occurring during a power excursion were studied in an out-of-pile loop with a water cooled channel at low pressure (1 to 4 atm. abs. ). Circular and rectangular test sections with electrically heated walls of two different thermal diffusivity materials(aluminium and stainless steel) were used. The rectangular test sections were 600 mm long, 35 mm wide and had a 2, 9 mm gap; they simulate two half plates of the M.T.R. fuel element. Natural or forced convection are possible in the test section; the water height above it can be varied from 2.8 to 8 meters and the maximum allowed pressure at its outlet is 4 atm. abs.The heating source is a series of lead batteries which is able to generate, for short periods of time, 85 volts and 25000 amperes; linear, square or exponential power rise versus time can be realized. A 14 channels tape recorder (0-10 000 Hz bandwidth; is used for the measurements of temperature (8/100 mm diameter thermocouple), pressure ('Statham' pressure transducers) and void fraction (X rays). More than 500 tests have been carried out. The influence of the initial water temperature, flow rate, pressure, water height on the water ejections, pressure variations and void fraction in the test section were studied. Tests with energies up to 3000 W/cm in 50 milliseconds were attempted. The energy above which the instabilities appear was determined. An interpretation of the observed phenomena and a simplified theoretical model are presented. [French] Les phenomenes thermiques et hydrodynamiques qui apparaissent au cours d'une excursion de puissance ont ete etudies sur un canal refroidi par de l'eau a basse pression situe sur une installation hors pile. On a utilise des sections d'essais de geometrie cylindrique ou parallipedique dont les parois chauffees par effet Joule sont constituees de materiaux de diffusivite calorifique differente (aluminium et acier inoxydable). La section d'essais parallipedique a 600 mm de long

  2. Study of the thermal and hydraulic phenomena occurring during power excursion on a heated test section; Etude des phenomenes thermiques et hydrauliques accompagnant une excursion rapide de puissance sur un canal chauffant

    Energy Technology Data Exchange (ETDEWEB)

    Nyer, M. [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1969-07-01

    The thermal and hydrodynamic phenomena occurring during a power excursion were studied in an out-of-pile loop with a water cooled channel at low pressure (1 to 4 atm. abs. ). Circular and rectangular test sections with electrically heated walls of two different thermal diffusivity materials(aluminium and stainless steel) were used. The rectangular test sections were 600 mm long, 35 mm wide and had a 2, 9 mm gap; they simulate two half plates of the M.T.R. fuel element. Natural or forced convection are possible in the test section; the water height above it can be varied from 2.8 to 8 meters and the maximum allowed pressure at its outlet is 4 atm. abs.The heating source is a series of lead batteries which is able to generate, for short periods of time, 85 volts and 25000 amperes; linear, square or exponential power rise versus time can be realized. A 14 channels tape recorder (0-10 000 Hz bandwidth; is used for the measurements of temperature (8/100 mm diameter thermocouple), pressure ('Statham' pressure transducers) and void fraction (X rays). More than 500 tests have been carried out. The influence of the initial water temperature, flow rate, pressure, water height on the water ejections, pressure variations and void fraction in the test section were studied. Tests with energies up to 3000 W/cm in 50 milliseconds were attempted. The energy above which the instabilities appear was determined. An interpretation of the observed phenomena and a simplified theoretical model are presented. [French] Les phenomenes thermiques et hydrodynamiques qui apparaissent au cours d'une excursion de puissance ont ete etudies sur un canal refroidi par de l'eau a basse pression situe sur une installation hors pile. On a utilise des sections d'essais de geometrie cylindrique ou parallipedique dont les parois chauffees par effet Joule sont constituees de materiaux de diffusivite calorifique differente (aluminium et acier inoxydable). La section d

  3. Validation of the U.S. NRC coupled code system TRITON/TRACE/PARCS with the special power excursion reactor test III (SPERT III)

    Energy Technology Data Exchange (ETDEWEB)

    Wang, R. C.; Xu, Y.; Downar, T. [Dept. of Nuclear Engineering and Radiological Sciences, Univ. of Michigan, Ann Arbor, MI 48104 (United States); Hudson, N. [RES Div., U.S. NRC, Rockville, MD (United States)

    2012-07-01

    The Special Power Excursion Reactor Test III (SPERT III) was a series of reactivity insertion experiments conducted in the 1950's. This paper describes the validation of the U.S. NRC Coupled Code system TRITON/PARCS/TRACE to simulate reactivity insertion accidents (RIA) by using several of the SPERT III tests. The work here used the SPERT III E-core configuration tests in which the RIA was initiated by ejecting a control rod. The resulting super-prompt reactivity excursion and negative reactivity feedback produced the familiar bell shaped power increase and decrease. The energy deposition during such a power peak has important safety consequences and provides validation basis for core coupled multi-physics codes. The transients of five separate tests are used to benchmark the PARCS/TRACE coupled code. The models were thoroughly validated using the original experiment documentation. (authors)

  4. Multiple fracture planes in deuteron irradiated metals

    International Nuclear Information System (INIS)

    Jones, W.R.; Johnson, P.B.

    1987-01-01

    Evidence has been found of multiple fracture planes in the blistering and flaking of metals observed at room temperature following irradiation at 120 K with 200 keV deuterons. In particular, two fracture planes are identified in copper, gold and stainless steel and three in aluminium. In nickel only one fracture plane is found. Qualitative models are proposed which explain the different fracture planes that are observed. In these models it is proposed that several mechanisms are important. (i) High levels of compressional stress in the implanted layer inhibits bubble nucleation and bubble growth in the depth region near the maxima in the damage and gas deposition profiles. (ii) The lateral stress varies from compression in the implant region to tension in the material below. In the region of tension bubble growth is enhanced. The vertical gradient in the lateral stress may also assist gas to move deeper into the target to further enhance bubble growth in this region. (iii) Shear resulting from differential expansion due to a combination of radiation induced swelling and localised heating is an important mechanism leading to fracture. (orig.)

  5. Copernican Revolution in the Complex Plane

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 17; Issue 11. Copernican Revolution in the Complex Plane - An Algebraic Way to Show the "Chief Point" of Copernican Innovation. Giorgio Goldoni. General Article Volume 17 Issue 11 November 2012 pp 1065-1084 ...

  6. Infrared MUSIC from Z technology focal planes

    International Nuclear Information System (INIS)

    Waters, C.R.; Sommese, A.; Johnston, D.; Landau, H.

    1989-01-01

    Presented is the Multiple Signal Classification (MUSIC) algorithm which uses the high frequency differences in sensed time signals to discriminate, count, and accurately locate closely spaced targets. Z technology focal planes allow the implementation of this algorithm and the trade-off between finer spatial resolution systems and systems with coarser resolution but higher sampling rates

  7. Construction of the STAR Event Plane Detector

    Science.gov (United States)

    Adams, Joseph

    2017-09-01

    The Event Plane Detector (EPD) is an upgrade to the STAR experiment at RHIC, providing high granularity and acceptance in the forward (2.2 run for commissioning. In this talk I will discuss the construction of the EPD, the installation of the quarter wheel, and plans for full installation in 2018.

  8. Ruler of the plane - Games of geometry

    NARCIS (Netherlands)

    Beekhuis, S.; Buchin, K.; Castermans, T.; Hurks, T.; Sonke, W.; Aronov, B.; Katz, M.J.

    2017-01-01

    Ruler of the Plane is a set of games illustrating concepts from combinatorial and computational geometry. The games are based on the art gallery problem, ham-sandwich cuts, the Voronoi game, and geometric network connectivity problems like the Euclidean minimum spanning tree and traveling

  9. Trigonometric Characterization of Some Plane Curves

    Indian Academy of Sciences (India)

    IAS Admin

    (Figure 1). A relation between tan θ and tanψ gives the trigonometric equation of the family of curves. In this article, trigonometric equations of some known plane curves are deduced and it is shown that these equations reveal some geometric characteristics of the families of the curves under consideration. In Section 2,.

  10. On Generalisation of Polynomials in Complex Plane

    Directory of Open Access Journals (Sweden)

    Maslina Darus

    2010-01-01

    Full Text Available The generalised Bell and Laguerre polynomials of fractional-order in complex z-plane are defined. Some properties are studied. Moreover, we proved that these polynomials are univalent solutions for second order differential equations. Also, the Laguerre-type of some special functions are introduced.

  11. Covariant quantum mechanics on a null plane

    International Nuclear Information System (INIS)

    Leutwyler, H.; Stern, J.

    1977-03-01

    Lorentz invariance implies that the null plane wave functions factorize into a kinematical part describing the motion of the system as a whole and an inner wave function that involves the specific dynamical properties of the system - in complete correspondence with the non-relativistic situation. Covariance is equivalent to an angular condition which admits non-trivial solutions

  12. Does monocular visual space contain planes?

    NARCIS (Netherlands)

    Koenderink, Jan J.; Albertazzi, Liliana; van Doorn, Andrea J.; van Ee, Raymond; van de Grind, Wim A.; Kappers, Astrid M L; Lappin, Joe S.; Farley Norman, J.; (Stijn) Oomes, A. H J; te Pas, Susan P.; Phillips, Flip; Pont, Sylvia C.; Richards, Whitman A.; Todd, James T.; Verstraten, Frans A J; de Vries, Sjoerd

    The issue of the existence of planes-understood as the carriers of a nexus of straight lines-in the monocular visual space of a stationary human observer has never been addressed. The most recent empirical data apply to binocular visual space and date from the 1960s (Foley, 1964). This appears to be

  13. In-plane user positioning indoors

    NARCIS (Netherlands)

    Jovanovic, N.; Özçelebi, T.; Lukkien, J.J.; Skoric, B.; Ignatenko, T.

    2014-01-01

    Indoor positioning is a service required by many smart environment applications for various purposes, such as activity classification, indoor navigation and context awareness. In this paper, we present a novel approach to the user positioning problem based on in-plane detection enabled by a set of

  14. Techniques to measure complex-plane fields

    CSIR Research Space (South Africa)

    Dudley, Angela L

    2014-09-25

    Full Text Available In this work we construct coherent superpositions of Gaussian and vortex modes which can be described to occupy the complex-plane. We demonstrate how these fields can be experimentally constructed in a digital, controllable manner with a spatial...

  15. Personnel thermoluminescent dosimetry of plane pilots

    International Nuclear Information System (INIS)

    Azorin V, J.C.; Rivera M, T.; Azorin N, J.

    1999-01-01

    In this work are presented the results of the research realized in the pilots of commercial planes of the different flight equipment existing. The results obtained show that the pilots receive during their work, doses of ionizing radiation greater than the limit recommended by the International Commission of Radiological Protection. (Author)

  16. Elastic Constants of Plane Orthotropic Elasticity

    DEFF Research Database (Denmark)

    Krenk, Steen

    1979-01-01

    The four independent material parameters of plane orthotropic elasti city are introduced as the effective stiffness, the effective Poisson ratio, the stiffness ratio and the shear parameter. It is proved that stress boundary value problems with zero resulting force on internal contours lead...

  17. Cues for localization in the horizontal plane

    DEFF Research Database (Denmark)

    Jeppesen, Jakob; Møller, Henrik

    2005-01-01

    manipulated in HRTFs used for binaural synthesis of sound in the horizontal plane. The manipulation of cues resulted in HRTFs with cues ranging from correct combinations of spectral information and ITDs to combinations with severely conflicting cues. Both the ITD and the spectral information seem...

  18. Locating a minisum circle in the plane

    DEFF Research Database (Denmark)

    Brimberg, Jack; Juel, Henrik; Schöbel, Anita

    2009-01-01

    We consider the problem of locating a circle with respect to existing facilities in the plane such that the sum of weighted distances between the circle and the facilities is minimized, i.e., we approximate a set of given points by a circle regarding the sum of weighted distances. If the radius...

  19. Crack initiation under generalized plane strain conditions

    International Nuclear Information System (INIS)

    Shum, D.K.M.; Merkle, J.G.

    1991-01-01

    A method for estimating the decrease in crack-initiation toughness, from a reference plane strain value, due to positive straining along the crack front of a circumferential flaw in a reactor pressure vessel is presented in this study. This method relates crack initiation under generalized plane strain conditions with material failure at points within a distance of a few crack-tip-opening displacements ahead of a crack front, and involves the formulation of a micromechanical crack-initiation model. While this study is intended to address concerns regarding the effects of positive out-of- plane straining on ductile crack initiation, the approach adopted in this work can be extended in a straightforward fashion to examine conditions of macroscopic cleavage crack initiation. Provided single- parameter dominance of near-tip fields exists in the flawed structure, results from this study could be used to examine the appropriateness of applying plane strain fracture toughness to the evaluation of circumferential flaws, in particular to those in ring-forged vessels which have no longitudinal welds. In addition, results from this study could also be applied toward the analysis of the effects of thermal streaming on the fracture resistance of circumferentially oriented flaws in a pressure vessel. 37 refs., 8 figs., 1 tab

  20. The impact of round window vs cochleostomy surgical approaches on interscalar excursions in the cochlea: Preliminary results from a flat-panel computed tomography study

    Directory of Open Access Journals (Sweden)

    Nicole T. Jiam

    2016-09-01

    Full Text Available Objective: To evaluate incidence of interscalar excursions between round window (RW and cochleostomy approaches for cochlear implant (CI insertion. Methods: This was a retrospective case-comparison. Flat-panel CT (FPCT scans for 8 CI users with Med-El standard length electrode arrays were collected. Surgical technique was identified by a combination of operative notes and FPCT imaging. Four cochleae underwent round window insertion and 4 cochleae underwent cochleostomy approaches anterior and inferior to the round window. Results: In our pilot study, cochleostomy approaches were associated with a higher likelihood of interscalar excursion. Within the cochleostomy group, we found 29% of electrode contacts (14 of 48 electrodes to be outside the scala tympani. On the other hand, 8.5% of the electrode contacts (4 of 47 electrodes in the round window insertion group were extra-scalar to the scala tympani. These displacements occurred at a mean angle of occurrence of 364° ± 133°, near the apex of the cochlea. Round window electrode displacements tend to localize at angle of occurrences of 400° or greater. Cochleostomy electrodes occurred at an angle of occurrence of 19°–490°. Conclusions: Currently, the optimal surgical approach for standard CI electrode insertion is highly debated, to a certain extent due to a lack of post-operative assessment of intracochlear electrode contact. Based on our preliminary findings, cochleostomy approach is associated with an increased likelihood of interscalar excursions, and these findings should be further evaluated with future prospective studies. Keywords: Cochlear implantation, Round window insertion, Cochleostomy, Interscalar excursion, Electrode position, Flat-panel computed tomography, Surgical approach

  1. 40Ar/ 39Ar, K-Ar and 230Th- 238U dating of the Laschamp excursion: A radioisotopic tie-point for ice core and climate chronologies

    Science.gov (United States)

    Singer, Brad S.; Guillou, Hervé; Jicha, Brian R.; Laj, Carlo; Kissel, Catherine; Beard, Brian L.; Johnson, Clark M.

    2009-08-01

    A brief period of enhanced 10Be flux that straddles the interstadial warm period known as Dansgaard-Oeschger event 10 in Greenland and its counterpart in Antarctica, the Antarctic Isotope Maximum 10 is but one consequence of the weakening of Earth's magnetic field associated with the Laschamp excursion. This 10Be peak measured in the GRIP ice core is dated at 41,250 y b2k (= before year 2000 AD) in the most recent GICC05 age model obtained from the NorthGRIP core via multi-parameter counting of annual layers. Uncertainty in the age of the 10Be peak is, however, no better than ± 1630 y at the 95% confidence level, reflecting accumulated error in identifying annual layers. The age of the Laschamp excursion [Guillou, H., Singer, B.S., Laj, C., Kissel, C., Scaillet, S., Jicha, B., 2004. On the age of the Laschamp geomagnetic excursion. Earth Planet. Sci. Lett. 227, 331-343.] is revised on the basis of new 40Ar/ 39Ar, unspiked K-Ar and 238U- 230Th data from three lava flows in the Massif Central, France, together with the 40Ar/ 39Ar age of a transitionally magnetized lava flow at Auckland, New Zealand. Combined, these data yield an age of 40,700 ± 950 y b2k, where the uncertainty includes both analytical and systematic ( 40K and 230Th decay constant) errors. Taking the radioisotopic age as a calibration tie point suggests that the layer-counting chronologies for the NorthGRIP and GISP2 ice cores are more accurate and precise than previously thought at depths corresponding to the Laschamp excursion.

  2. SIMMER-III parametric studies of fuel-steel mixing and radial mesh effects on power excursion in ESFR ULOF transients - 15033

    International Nuclear Information System (INIS)

    Chen, X.N.; Rineiski, A.; Gabrielli, F.; Andriolo, L.; Li, R.; Maschek, W.

    2015-01-01

    This paper deals with SIMMER-III once-through simulations of the first power excursion initiated by an unprotected loss of flow (ULOF) in the Working Horse design of the European Sodium Cooled Fast Reactor (ESFR). Since the sodium void effect is strictly positive in this core and dominant in the transient, a power excursion is initiated by sodium boiling in the ULOF case. Two major effects, namely (1) reactivity effects due to fuel-steel mixing after melting and (2) the radial mesh size, which were not considered initially in SIMMER simulations for ESFR, are studied. The first effect concerns the reactivity difference between the heterogeneous fuel/clad/wrapper configuration and the homogeneous mixture of steel and fuel. The full core homogenization (due to melting) effect is ∼ 2 dollars, though a smaller effect takes place in case of partial core melting. The second effect is due to the SIMMER sub-assembly coarse mesh treatment, where a simultaneous sodium boiling onset in all sub-assemblies belonging to one ring leads to an overestimated reactivity ramp. For investigating the influence of fuel/steel mixing effects, a lumped 'homogenization' reactivity feedback has been introduced, being proportional to the molten steel mass. For improving the coarse mesh treatment, we employ finer radial meshes to take the subchannel effects into account, where the side and interior channels have different coolant velocities and temperatures. The simulation results show that these two effects have significant impacts on the first power excursion after the sodium boiling: both effects delay the power excursion and significantly reduce the height of the power peaks in case of a ULOF

  3. Effect of hamstring flexibility on hip and lumbar spine joint excursions during forward-reaching tasks in participants with and without low back pain.

    Science.gov (United States)

    Johnson, Erica N; Thomas, James S

    2010-07-01

    To examine the correlation between hamstring flexibility and hip and lumbar spine joint excursions during standardized reaching and forward-bending tasks. Retrospective analysis of data obtained during 2 previous prospective studies that examined kinematics and kinetics during forward-reaching tasks in participants with and without low back pain (LBP). The 2 previous studies were conducted in the Motor Control Lab at Ohio University and the Orthopaedic Ergonomics Laboratory at The Ohio State University. Data from a total of 122 subjects from 2 previous studies: study 1: 86 subjects recovered from an episode of acute LBP (recovered) and study 2 (A.I. McCallum, unpublished data): 18 chronic LBP subjects and 18 healthy-matched controls (healthy). Not applicable. Correlation values between hamstring flexibility as measured by straight leg raise (SLR) and amount of hip and lumbar spine joint excursions used during standardized reaching and forward-bending tasks. No significant correlation was found between hamstring flexibility and hip and lumbar joint excursions during forward-bending tasks in the LBP or recovered groups. The SLR had a significant negative correlation with lumbar spine excursions during reaching tasks to a low target in the healthy group (right SLR: P=.011, left SLR: P=.004). Hamstring flexibility is not strongly related to the amount of lumbar flexion used to perform forward-reaching tasks in participants who have chronic LBP or who have recovered from LBP. More research needs to be conducted to examine the influence of hamstring flexibility on observed movement patterns to further evaluate the efficacy of flexibility training in the rehabilitation of patients with LBP. Copyright 2010 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

  4. Sagittal plane gait characteristics in hip osteoarthritis patients with mild to moderate symptoms compared to healthy controls: a cross-sectional study

    Directory of Open Access Journals (Sweden)

    Eitzen Ingrid

    2012-12-01

    Full Text Available Abstract Background Existent biomechanical studies on hip osteoarthritic gait have primarily focused on the end stage of disease. Consequently, there is no clear consensus on which specific gait parameters are of most relevance for hip osteoarthritis patients with mild to moderate symptoms. The purpose of this study was to explore sagittal plane gait characteristics during the stance phase of gait in hip osteoarthritis patients not eligible for hip replacement surgery. First, compared to healthy controls, and second, when categorized into two subgroups of radiographic severity defined from a minimal joint space of ≤/>2 mm. Methods Sagittal plane kinematics and kinetics of the hip, knee and ankle joint were calculated for total joint excursion throughout the stance phase, as well as from the specific events initial contact, midstance, peak hip extension and toe-off following 3D gait analysis. In addition, the Western Ontario and McMaster Universities Osteoarthritis Index, passive hip range of motion, and isokinetic muscle strength of hip and knee flexion and extension were included as secondary outcomes. Data were checked for normality and differences evaluated with the independent Student’s t-test, Welch’s t-test and the independent Mann–Whitney U-test. A binary logistic regression model was used in order to control for velocity in key variables. Results Fourty-eight hip osteoarthritis patients and 22 controls were included in the final material. The patients walked significantly slower than the controls (p=0.002, revealed significantly reduced joint excursions of the hip (pp=0.011, and a reduced hip flexion moment at midstance and peak hip extension (p2 mm suggested that the observed deviations were more pronounced in patients with greater radiographic severity. The biomechanical differences were, however, not reflected in self-reported symptoms or function. Conclusions Reduced gait velocity, reduced sagittal plane joint excursion, and

  5. Ischemic preconditioning of the lower extremity attenuates the normal hypoxic increase in pulmonary artery systolic pressure.

    Science.gov (United States)

    Foster, Gary P; Westerdahl, Daniel E; Foster, Laura A; Hsu, Jeffrey V; Anholm, James D

    2011-12-15

    Ischemic pre-condition of an extremity (IPC) induces effects on local and remote tissues that are protective against ischemic injury. To test the effects of IPC on the normal hypoxic increase in pulmonary pressures and exercise performance, 8 amateur cyclists were evaluated under normoxia and hypoxia (13% F(I)O(2)) in a randomized cross-over trial. IPC was induced using an arterial occlusive cuff to one thigh for 5 min followed by deflation for 5 min for 4 cycles. In the control condition, the resting pulmonary artery systolic pressure (PASP) increased from a normoxic value of 25.6±2.3 mmHg to 41.8±7.2 mmHg following 90 min of hypoxia. In the IPC condition, the PASP increased to only 32.4±3.1 mmHg following hypoxia, representing a 72.8% attenuation (p=0.003). No significant difference was detected in cycle ergometer time trial duration between control and IPC conditions with either normoxia or hypoxia. IPC administered prior to hypoxic exposure was associated with profound attenuation of the normal hypoxic increase of pulmonary artery systolic pressure. Published by Elsevier B.V.

  6. Older Women with Controlled Isolated Systolic Hypertension: Exercise and Blood Pressure.

    Science.gov (United States)

    Ubolsakka-Jones, Chulee; Sangthong, Benjarat; Aueyingsak, Sahachat; Jones, David A

    2016-06-01

    Exercise is generally regarded as beneficial for health, but the consequent increases in blood pressure might pose a risk for hypertensive subjects. The purpose of this study was to determine blood pressure responses to dynamic exercise and sustained handgrip in patients with isolated systolic hypertension (ISH) who were stable on medication. Nineteen female ISH patients (66 ± 5 yr) and 19 age-matched normotensive (NT) female controls undertook a 5-min cycle exercise (60% heart rate reserve [HRR]) and a 2-min handgrip exercise (30% maximum voluntary contraction). Blood pressure responses were measured using an oscillometric cuff, together with heart rate and resting brachial pulse transit times. Systolic blood pressure (SBP) levels after cycle exercise were 194 ± 18 and 153 ± 19 mm Hg for ISH and NT, respectively, with the increase above resting being greater for ISH (P exercise, SBP rose to 168 ± 19 and 140 ± 8 mm Hg for ISH and NT, respectively. The increases above baseline were greater for ISH both during the exercise and postexercise circulatory occlusion (P = 0.017). The increase in DBP levels during exercise and postexercise occlusion were similar in ISH and NT, suggesting little difference in metaboreflex sensitivity. Pulse transit time was shorter for ISH compared with NT (166 ± 6 ms and 242 ± 24 ms, respectively, P exercises, which may constitute a risk for cardiovascular incidents.

  7. VLSI design of an RSA encryption/decryption chip using systolic array based architecture

    Science.gov (United States)

    Sun, Chi-Chia; Lin, Bor-Shing; Jan, Gene Eu; Lin, Jheng-Yi

    2016-09-01

    This article presents the VLSI design of a configurable RSA public key cryptosystem supporting the 512-bit, 1024-bit and 2048-bit based on Montgomery algorithm achieving comparable clock cycles of current relevant works but with smaller die size. We use binary method for the modular exponentiation and adopt Montgomery algorithm for the modular multiplication to simplify computational complexity, which, together with the systolic array concept for electric circuit designs effectively, lower the die size. The main architecture of the chip consists of four functional blocks, namely input/output modules, registers module, arithmetic module and control module. We applied the concept of systolic array to design the RSA encryption/decryption chip by using VHDL hardware language and verified using the TSMC/CIC 0.35 m 1P4 M technology. The die area of the 2048-bit RSA chip without the DFT is 3.9 × 3.9 mm2 (4.58 × 4.58 mm2 with DFT). Its average baud rate can reach 10.84 kbps under a 100 MHz clock.

  8. Right ventricular systolic and diastolic function at rest in patients with coronary artery disease

    International Nuclear Information System (INIS)

    Caglar, N.M.; Araki, Haruo; Taira, Yuji; Fukuyama, Takaya; Nakamura, Motoomi

    1985-01-01

    Right ventricular systolic and diastolic function was studied in patients with ischemic heart disease using equilibrium radionuclide ventriculography. In patients with inferior myocardial infarction and proximal right coronary lesions, the right ventricular ejection fraction (0.43+-0.06, n=10, mean+-SD) and peak filling rate (1.7+-0.4 EDV/sec) were lower than normals (0.57+-0.07 and 2.7+-0.4 EDV/sec, n=10, p<0.001, respectively). In these patients, the right ventricular time to peak filling rate was longer than in normals (225+-36 msec vs 136+-45 msec, p<0.001), while the left ventricular ejection fraction remained normal. In patients with inferior myocardial infarction and distal right coronary lesions, the right ventricular ejection fraction, peak filling rate and time to peak filling rate were not different from those in normals. Even in patients with proximal right coronary lesions, the right ventricular ejection fraction was normal unless they had an inferior myocardial infarction. A decreased left ventricular ejection fraction and abnormal motion of the ventricular septum did not affect the right ventricular ejection fraction. The present results suggest that patients with an inferior myocardial infarction and proximal right coronary lesion often develop right ventricular systolic and diastolic dysfunction. (author)

  9. Retinopathy of Prematurity Is Associated with Increased Systolic Blood Pressure in Adults Who Were Born Preterm.

    Science.gov (United States)

    Kistner, Anna; Jacobson, Lena; Östergren, Jan; Hellström, Ann

    2017-01-01

    Adults born preterm are at risk of developing cardiovascular morbidities. The aim of this study was to evaluate the relationship between retinopathy of prematurity (ROP) and blood pressure (BP) and salivary cortisol levels during adulthood. Sixty-nine subjects (mean age 22.6 years) were included. Subjects were adults who were: (a) ex-preterm infants with severe ROP (n = 22), born at gestational age (GA) <30 weeks with a birth weight (BW) <1,000 g, (b) ex-preterm infants with no/mild ROP (n = 21), born at GA <28 weeks with a BW <1,000 g, or (c) full-term controls (n = 26). Anthropometric data, office BP, ambulatory BP, and morning and evening salivary cortisol were analyzed. As adults, ex-preterm infants with severe ROP had on average 7.4 mm Hg higher systolic office BP than those with no/mild ROP (p = 0.019) and controls (p = 0.007). A high cortisol level, tall height, and severe ROP were independent predictors of higher ambulatory systolic BP during adulthood in forward stepwise regression analysis, independent of GA. Our results indicate that preterm infants with severe abnormal retinal vascular development during the neonatal period may be at an increased risk for increased BP during adulthood. We found no differences between those with no/mild ROP as infants and controls with regard to BP data. © 2017 The Author(s) Published by S. Karger AG, Basel.

  10. Effect of Sex on Reverse Remodeling in Chronic Systolic Heart Failure.

    Science.gov (United States)

    Aimo, Alberto; Vergaro, Giuseppe; Castiglione, Vincenzo; Barison, Andrea; Pasanisi, Emilio; Petersen, Christina; Chubuchny, Vladyslav; Giannoni, Alberto; Poletti, Roberta; Maffei, Silvia; Januzzi, James L; Passino, Claudio; Emdin, Michele

    2017-10-01

    This study sought to investigate sex-related differences in reverse remodeling (RR). RR, that is, the recovery from left ventricular (LV) dilation and dysfunction in response to treatment for heart failure (HF), is associated with improved prognosis. Data from patients with stable systolic HF (LV ejection fraction [LVEF] of sex. Women showed a higher incidence of RR (41% vs. 27%, respectively; p 35%, according to current indication for device implantation, and LVEF definition of HF with reduced or mid-range EF). In the whole population, female sex was an independent predictor of RR (hazard ratio: 1.54; 95% confidence interval: 1.11 to 2.14; p = 0.011), together with cause of HF, disease duration, and left bundle branch block. Female sex was again an independent predictor of RR in all LVEF categories. Reverse remodeling is more frequent among women, regardless of cause and severity of LV dysfunction. Female sex is an independent predictor of RR in all categories of LV systolic dysfunction. Copyright © 2017 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

  11. Predictors of systolic BP benazepril plus amlodipine or hydrochlorothiazide) in the ACCOMPLISH Study.

    Science.gov (United States)

    Kjeldsen, Sverre E; Jamerson, Kenneth A; Bakris, George L; Pitt, Bertram; Dahlöf, Björn; Velazquez, Eric J; Hua, Tsushung A; Kelly, Roxzana Y; Zappe, Dion; Hester, Allen; Tuomilehto, Jaakko; Ostergren, Jan; Ibsen, Hans; Weber, Michael

    2012-04-01

    The ACCOMPLISH Trial investigated intensive antihypertensive combination treatment with benazepril + amlodipine (B+A) or benazepril + hydrochlorothiazide (B+H) on cardiovascular outcomes in patients with systolic hypertension. We analyzed the baseline predictors of achieving a systolic blood pressure (SBP) Nordic region) and Caucasian ethnicity in both randomization arms. A higher diastolic BP and the use of lipid lowering agents indicated favorable effects in the B+H arm only. The predictors of uncontrolled SBP were: (i) higher baseline SBP values, (ii) higher number of previous antihypertensive medications in both arms, (iii) the previous use of insulin in the B+A arm, and (iv) pre-trial calcium channel blocker (CCB) use in the B+H arm. Additionally, pre-trial use of thiazides and electrocardiogram (ECG)-left ventricular hypertrophy (LVH) at baseline predicted higher, and smoking lower absolute SBP in the B+A arm and the use of thiazides and proteinuria a higher SBP in the B+H arm. Irrespective of treatment, patients in the USA and Caucasians achieved better SBP control, whereas higher baseline SBP and more previous antihypertensive medications indicated less control. Concomitant use of lipid lowering treatment indicated a better SBP control in the benazepril + hydrochlorothiazide arm. Lastly, insulin use and ECG-LVH in the benazepril + amlodipine arm and proteinuria in the benazepril + hydrochlorothiazide arm indicated poor control.

  12. Hypertension Treatment and Concern About Falling: Baseline Data from the Systolic Blood Pressure Intervention Trial.

    Science.gov (United States)

    Berlowitz, Dan R; Breaux-Shropshire, Tonya; Foy, Capri G; Gren, Lisa H; Kazis, Lewis; Lerner, Alan J; Newman, Jill C; Powell, James R; Riley, William T; Rosman, Robert; Wadley, Virginia G; Williams, Julie A

    2016-11-01

    To determine the extent of concern about falling in older adults with hypertension, whether lower blood pressure (BP) and greater use of antihypertensive medications are associated with greater concern about falling, and whether lower BP has a greater effect on concern about falling in older and more functionally impaired individuals. Secondary analysis involving cross-sectional study of baseline characteristics of participants enrolled in the Systolic Blood Pressure Intervention Trial (SPRINT). Approximately 100 outpatient sites. SPRINT enrollees aged 50 and older (mean age 69) diagnosed with hypertension (N = 2,299). Concern about falling was determined using the shortened version of the Falls Efficacy Scale International as measured at the baseline examination. Mild concern about falling was present in 29.3% of participants and moderate to severe concern in 17.9%. Neither low BP (systolic BPconcern about falling (P > .10). Participants with moderate to severe concern about falling were taking significantly more antihypertensive medications than those with mild or no concern. After adjusting for baseline characteristics, no associations were evident between BP, medications, and concern about falling. Results were similar in older and younger participants; interactions between BP and age and functional status were not significantly associated with concern about falling. Although concern about falling is common in older adults with hypertension, it was not found to be associated with low BP or use of more antihypertensive medications in baseline data from SPRINT. © 2016, Copyright the Authors Journal compilation © 2016, The American Geriatrics Society.

  13. Impedance cardiography: a comparison of cardiac output vs waveform analysis for assessing left ventricular systolic dysfunction.

    Science.gov (United States)

    DeMarzo, Arthur P; Kelly, Russell F; Calvin, James E

    2007-01-01

    Early detection of asymptomatic left ventricular systolic dysfunction (LVSD) is beneficial in managing heart failure. Recent studies have cast doubt on the usefulness of cardiac output as an indicator of LVSD. In impedance cardiography (ICG), the dZ/dt waveform has a systolic wave called the E wave. This study looked at measurements of the amplitude and area of the E wave compared with ICG-derived cardiac output, stroke volume, cardiac index, and stroke index as methods of assessing LVSD. ICG data were obtained from patients (n=26) admitted to a coronary care unit. Clinical LVSD severity was stratified into 4 groups (none, mild, moderate, and severe) based on echocardiography data and standard clinical assessment by a cardiologist blinded to ICG data. Statistical analysis showed that the E wave amplitude and area were better indicators of the level of LVSD than cardiac output, stroke volume, cardiac index, or stroke index. ICG waveform analysis has potential as a simple point-of-care test for detecting LVSD in asymptomatic patients at high risk for developing heart failure and for monitoring LVSD in patients being treated for heart failure.

  14. Effect of Right Heart Systolic Function on Outcomes in Patients with Constrictive Pericarditis Undergoing Pericardiectomy

    Directory of Open Access Journals (Sweden)

    Xue Lin

    2016-01-01

    Full Text Available Background: To determine the influence of right ventricular function in patients with constrictive pericarditis (CP undergoing surgery and to compare the outcomes of patients who received surgery with those managed medically. Methods: Patients with the diagnosis of CP and healthy volunteers were recruited from January 2006 to November 2011. Patients with CP chose to either receive pericardiectomy or medical management. Echocardiographic measurements were performed to evaluate heart function, and survival was recorded. Results: A total of 58 patients with CP (36 received pericardiectomy, 22 managed medically, and 43 healthy volunteers were included. CP patients who received surgery had a higher survival rate than those managed medically (P = 0.003, and higher survival was also seen in the subgroup of CP patients with severely impaired right systolic function. Albumin level, left ventricular end-diastolic dimension, and tricuspid regurgitation velocity were associated with survival in CP patients who received surgery. Conclusions: Preoperative right heart function does not affect surgical outcomes. Patients with severely impaired preoperative right systolic function obtain a greater survival advantage with surgery than with medical treatment.

  15. The measurement of digital systolic blood pressure by strain gauge technique

    DEFF Research Database (Denmark)

    Nielsen, P E; Bell, G; Lassen, N A

    1972-01-01

    The systolic blood pressure on the finger, toe, and ankle has been measured by a strain gauge technique in 10 normal subjects aged 17-31 years and 14 normal subjects aged 43-57 years. The standard deviation in repeated measurements lies between 2 and 6 mm Hg. The finger pressure in the younger...... group was significantly higher than the corresponding arm pressure (+ 9.3 mm Hg, S.D. 6.8), but equalled this in the older group (- 0.5 mm Hg, S.D. 6.6). In the two groups the ankle pressures were + 19.3 mm Hg (S.D. 7.5) and + 23.6 mm Hg (S.D. 9.5) higher than the systolic arm pressures. The toe...... pressures were lower than the arm pressures, in the two groups - 4.8 mm Hg (S.D. 6.6) and - 9.8 mm Hg (S.D. 10.7) respectively. The ankle-toe gradient was in the younger group 24.3 mm Hg (S.D. 7.3) and in the older group 33.3 mm Hg (S.D. 12.1). Using mean minus 2.5 X S.D. as the lower limit of normality...

  16. Relationship of hemoglobin and hematocrit to systolic function in advanced heart failure.

    Science.gov (United States)

    Guglin, Maya; Darbinyan, Nellie

    2012-01-01

    The dataset from the Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness (ESCAPE) trial provides a rare opportunity to evaluate the whole spectrum of associations of hemoglobin (HB) and hematocrit (HCT) in heart failure (HF). In that trial, subjective and objective data were recorded at multiple time points when HB and HCT were also measured. We investigated the relationship between anemia and ventricular systolic function. A limited access dataset from the ESCAPE trial, provided by the National Heart, Lung and Blood Institute, was analyzed. Linear regression analysis, correlation coefficients and Student's t test were utilized. Besides the known association of anemia with poor prognosis, more severe symptoms, decreased functional capacity and impaired kidney function, we found a significant and very consistent inverse correlation between HB and HCT and ventricular contractility. Both left ventricular ejection fraction and right ventricular fractional area change improved with a decrease in HB and vice versa. We hypothesize that this effect can result from a change in viscosity, which decreases with a decrease in HCT, and may facilitate adaptation of the heart to a volume overload state accompanied by hemodilution. In HF, anemia is associated with poor prognosis and functional impairment, but also with mildly improved systolic function. It may represent an adaptive reaction to congestion. Copyright © 2012 S. Karger AG, Basel.

  17. Doppler ultrasound surveillance in deep tunneling compressed-air work with Trimix breathing: bounce dive technique compared to saturation-excursion technique.

    Science.gov (United States)

    Vellinga, T P van Rees; Sterk, W; de Boer, A G E M; van der Beek, A J; Verhoeven, A C; van Dijk, F J H

    2008-01-01

    The Western Scheldt Tunneling Project in The Netherlands provided a unique opportunity to evaluate two deep-diving techniques with Doppler ultrasound surveillance. Divers used the bounce diving techniques for repair and maintenance of the TBM. The tunnel boring machine jammed at its deepest depth. As a result the work time was not sufficient. The saturation diving technique was developed and permitted longer work time at great depth. Thirty-one divers were involved in this project. Twenty-three divers were examined using Doppler ultrasound. Data analysis addressed 52 exposures to Trimix at 4.6-4.8 bar gauge using the bounce technique and 354 exposures to Trimix at 4.0-6.9 bar gauge on saturation excursions. No decompression incidents occurred with either technique during the described phase of the project. Doppler ultrasound revealed that the bubble loads assessed in both techniques were generally low. We find out, that despite longer working hours, shorter decompression times and larger physical workloads, the saturation-excursion technique was associated with significant lower bubble grades than in the bounce technique using Doppler Ultrasound. We conclude that the saturation-excursion technique with Trimix is a good option for deep and long exposures in caisson work. The Doppler technique proved valuable, and it should be incorporated in future compressed-air work.

  18. Comparison of excursive occlusal force parameters in post-orthodontic and non-orthodontic subjects using T-Scan® III.

    Science.gov (United States)

    Qadeer, Sarah; Abbas, Ahmed A; Sarinnaphakorn, Lertrit; Kerstein, Robert B

    2018-01-01

    Published studies indicate that orthodontically treated patients demonstrate increased posterior occlusal friction contributing to temporomandibular disorder (TMD) symptoms. This study investigated measured excursive movement occlusal contact parameters and their association with TMD symptoms between non- and post-orthodontic subjects. Twenty-five post-orthodontic and 25 non-orthodontic subjects underwent T-Scan® computerized occlusal analysis to determine their disclusion time (DT), the excursive frictional contacts, and occlusal scheme. Each subject answered a TMD questionnaire to determine the presence or absence of TMD symptoms. Statistical analysis compared the within group and between group differences (p orthodontic and 1.36 s in the non-orthodontic group. In the non-orthodontic group, 72.7% working and 27.3% non-working side contacts were seen, while in the post-orthodontic group, (near equal) 54.7% working and 45.3% non-working side contacts were seen. Presence of canine guidance was seen in 60% of the non-orthodontic group and 24% in the post-orthodontic group. Seventy-two percent of the post orthodontics subjects presented with one or more TMD symptoms. Significantly longer disclusion time, higher posterior frictional contacts, and more TMD symptoms were observed in the post-orthodontic group, suggesting that orthodontic treatment increases posterior tooth friction. Computerized occlusal analysis is an objective diagnostic tool determining the quality of excursive movements following orthodontic treatment.

  19. Origin of the Local Group satellite planes

    Science.gov (United States)

    Banik, Indranil; O'Ryan, David; Zhao, Hongsheng

    2018-04-01

    We attempt to understand the planes of satellite galaxies orbiting the Milky Way (MW) and M31 in the context of Modified Newtonian Dynamics (MOND), which implies a close MW-M31 flyby occurred ≈8 Gyr ago. Using the timing argument, we obtain MW-M31 trajectories consistent with cosmological initial conditions and present observations. We adjust the present M31 proper motion within its uncertainty in order to simulate a range of orbital geometries and closest approach distances. Treating the MW and M31 as point masses, we follow the trajectories of surrounding test particle disks, thereby mapping out the tidal debris distribution. Around each galaxy, the resulting tidal debris tends to cluster around a particular orbital pole. We find some models in which these preferred spin vectors align fairly well with those of the corresponding observed satellite planes. The radial distributions of material in the simulated satellite planes are similar to what we observe. Around the MW, our best-fitting model yields a significant fraction (0.22) of counter-rotating material, perhaps explaining why Sculptor counter-rotates within the MW satellite plane. In contrast, our model yields no counter-rotating material around M31. This is testable with proper motions of M31 satellites. In our best model, the MW disk is thickened by the flyby 7.65 Gyr ago to a root mean square height of 0.75 kpc. This is similar to the observed age and thickness of the Galactic thick disk. Thus, the MW thick disk may have formed together with the MW and M31 satellite planes during a past MW-M31 flyby.

  20. Instability of in-plane vortices in two-dimensional easy-plane ferromagnets

    International Nuclear Information System (INIS)

    Wysin, G.M.

    1994-01-01

    An analysis of the core region of an in-plane vortex in the two-dimensional Heisenberg model with easy-plane anisotropy λ=J z /J xy leads to a clear understanding of the instability towards transformation into an out-of-plane vortex as a function of anisotropy. The anisotropy parameter λ c at which the in-plane vortex becomes unstable and develops into an out-of-plane vortex is determined with an accuracy comparable to computer simulations for square, hexagonal, and triangular lattices. For λ c , the in-plane vortex is stable but exhibits a normal mode whose frequency goes to zero as ω∝(λ c -λ) 1/2 as λ approaches λ c . For λ>λ c , the static nonzero out-of-plane spin components grow as (λ-λ c ) 1/2 . The lattice dependence of λ c is determined strongly by the number of spins in the core plaquette, is fundamentally a discreteness effect, and cannot be obtained in a continuum theory

  1. Determining the ice-binding planes of antifreeze proteins by fluorescence-based ice plane affinity.

    Science.gov (United States)

    Basu, Koli; Garnham, Christopher P; Nishimiya, Yoshiyuki; Tsuda, Sakae; Braslavsky, Ido; Davies, Peter

    2014-01-15

    Antifreeze proteins (AFPs) are expressed in a variety of cold-hardy organisms to prevent or slow internal ice growth. AFPs bind to specific planes of ice through their ice-binding surfaces. Fluorescence-based ice plane affinity (FIPA) analysis is a modified technique used to determine the ice planes to which the AFPs bind. FIPA is based on the original ice-etching method for determining AFP-bound ice-planes. It produces clearer images in a shortened experimental time. In FIPA analysis, AFPs are fluorescently labeled with a chimeric tag or a covalent dye then slowly incorporated into a macroscopic single ice crystal, which has been preformed into a hemisphere and oriented to determine the a- and c-axes. The AFP-bound ice hemisphere is imaged under UV light to visualize AFP-bound planes using filters to block out nonspecific light. Fluorescent labeling of the AFPs allows real-time monitoring of AFP adsorption into ice. The labels have been found not to influence the planes to which AFPs bind. FIPA analysis also introduces the option to bind more than one differently tagged AFP on the same single ice crystal to help differentiate their binding planes. These applications of FIPA are helping to advance our understanding of how AFPs bind to ice to halt its growth and why many AFP-producing organisms express multiple AFP isoforms.

  2. The diode pump: its application to nuclear particle counting and to the detection of rapid neutronic power excursions in atomic piles (1962); La pompe a diodes, son application au comptage de particules nucleaires et a la detection des excursions rapides de puissance neutronique d'une pile atomique (1962)

    Energy Technology Data Exchange (ETDEWEB)

    Nicolo, G [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1962-05-15

    This work deals in particular with three applications of an electronic device whose principle is based on that of the diode pump. 1- Linear response circuit 2- Logarithmic response circuit 3- Detection of neutronic power excursions in atomic piles using a circuit or a combination of several circuits of the linear response type. Each of the applications has been studied theoretically and experimentally. Finally, the detection of rapid power excursions is extensively discussed with reference to the many methods available, emphasis being laid on the rapidity of the electronic response. (author) [French] Cet ouvrage traite plus particulierement de trois applications d'un dispositif electronique dont le principe de fonctionnement est base sur celui de la pompe a diodes. 1- Circuit a reponse lineaire 2- Circuit a reponse logarithmique 3- Detection des excursions de puissance neutronique d'une pile atomique a l'aide d'un circuit ou d'une association de plusieurs circuits a reponse lineaire. Chacune des applications fait l'objet d'une etude theorique et experimentale. Enfin, la detection des excursions rapides de puissance est tres largement discutee a travers plusieurs methodes, notamment sur la partie concernant la rapidite de reponse de l'electronique. (auteur)

  3. Relationship between selected measures of strength and hip and knee excursion during unilateral and bilateral landings in women.

    Science.gov (United States)

    McCurdy, Kevin; Walker, John; Armstrong, Rusty; Langford, George

    2014-09-01

    The purpose of this study was to compare the relationship between several measures of single-joint, isometric, eccentric, and squat strength and unilateral and bilateral landing mechanics at the hip and knee in women. Twenty six healthy female subjects with previous athletic experience (height, 165.1 ± 7.01 cm; mass, 60.91 ± 7.14 kg; age, 20.9 ± 1.62 years) participated in this study. Hip and knee mechanics were measured using the MotionMonitor capture system (Innovative Sports Training, Inc.) with 3-dimensional electromagnetic sensors during bilateral (60 cm) and unilateral drop jumps (30 cm). On a separate day, isometric hip extension, external rotation, and abduction strength (lbs) were measured using a handheld dynamometer (Hoggan Health Industries, Inc.). Eccentric and isometric knee strength were measured on the Biodex IV Isokinetic Dynamometer (Biodex Medical Systems, Inc.). Free weight was used to measure the bilateral squat and a modified single-leg squat. The strongest correlations were found between squat strength and knee valgus (-0.77 ≤ r ≤ -0.83) and hip adduction (-0.5 ≤ r ≤ -0.65). After controlling for squat strength, hip external rotation strength and unilateral knee valgus (-0.41), hip abduction strength and bilateral knee valgus (-0.43), and knee flexion strength and bilateral hip adduction (-0.57) remained significant. Eccentric knee flexion strength and unilateral knee internal rotation was the only significant correlation for eccentric strength (-0.40). Squat strength seems to be the best predictor of knee valgus and was consistently related to hip adduction. Isometric and eccentric measures demonstrated few significant correlations with hip and knee excursion while demonstrating a low-to-moderate relationship. Hip and knee flexion and rotation do not seem to be related to strength. Squat strength should receive consideration during risk assessment for noncontact knee injury.

  4. NGC 404: A REJUVENATED LENTICULAR GALAXY ON A MERGER-INDUCED, BLUEWARD EXCURSION INTO THE GREEN VALLEY

    International Nuclear Information System (INIS)

    Thilker, David A.; Bianchi, Luciana; Schiminovich, David; Gil de Paz, Armando; Seibert, Mark; Madore, Barry F.; Wyder, Ted; Barlow, Tom; Conrow, Tim; Forster, Karl; Friedman, Peter; Martin, Chris; Morrissey, Patrick; Small, Todd; Rich, R. Michael; Yi, Sukyoung; Neff, Susan

    2010-01-01

    We have discovered recent star formation in the outermost portion ((1-4) x R 25 ) of the nearby lenticular (S0) galaxy NGC 404 using Galaxy Evolution Explorer UV imaging. FUV-bright sources are strongly concentrated within the galaxy's H I ring (formed by a merger event according to del RIo et al.), even though the average gas density is dynamically subcritical. Archival Hubble Space Telescope imaging reveals resolved upper main-sequence stars and conclusively demonstrates that the UV light originates from recent star formation activity. We present FUV, NUV radial surface brightness profiles, and integrated magnitudes for NGC 404. Within the ring, the average star formation rate (SFR) surface density (Σ SFR ) is ∼2.2 x 10 -5 M sun yr -1 kpc -2 . Of the total FUV flux, 70% comes from the H I ring which is forming stars at a rate of 2.5 x 10 -3 M sun yr -1 . The gas consumption timescale, assuming a constant SFR and no gas recycling, is several times the age of the universe. In the context of the UV-optical galaxy color-magnitude diagram, the presence of the star-forming H I ring places NGC 404 in the green valley separating the red and blue sequences. The rejuvenated lenticular galaxy has experienced a merger-induced, disk-building excursion away from the red sequence toward bluer colors, where it may evolve quiescently or (if appropriately triggered) experience a burst capable of placing it on the blue/star-forming sequence for up to ∼1 Gyr. The green valley galaxy population is heterogeneous, with most systems transitioning from blue to red but others evolving in the opposite sense due to acquisition of fresh gas through various channels.

  5. The Paleocene Eocene carbon isotope excursion in higher plant organic matter: Differential fractionation of angiosperms and conifers in the Arctic

    Science.gov (United States)

    Schouten, Stefan; Woltering, Martijn; Rijpstra, W. Irene C.; Sluijs, Appy; Brinkhuis, Henk; Sinninghe Damsté, Jaap S.

    2007-06-01

    A study of upper Paleocene-lower Eocene (P-E) sediments deposited on the Lomonosov Ridge in the central Arctic Ocean reveals relatively high abundances of terrestrial biomarkers. These include dehydroabietane and simonellite derived from conifers (gymnosperms) and a tetra-aromatic triterpenoid derived from angiosperms. The relative percentage of the angiosperm biomarker of the summed angiosperm + conifer biomarkers was increased at the end of the Paleocene-Eocene thermal maximum (PETM), different when observed with pollen counts which showed a relative decrease in angiosperm pollen. Stable carbon isotopic analysis of these biomarkers shows that the negative carbon isotope excursion (CIE) during the PETM amounts to 3‰ for both conifer biomarkers, dehydroabietane and simonellite, comparable to the magnitude of the CIE inferred from marine carbonates, but significantly lower than the 4.5‰ of the terrestrial C 29n-alkane [M. Pagani, N. Pedentchouk, M. Huber, A. Sluijs, S. Schouten, H. Brinkhuis, J.S. Sinninghe Damsté, G.R. Dickens, and the IODP Expedition 302 Expedition Scientists (2006), Arctic's hydrology during global warming at the Paleocene-Eocene thermal maximum. Nature, 442, 671-675.], which is a compound sourced by both conifers and angiosperms. Conspicuously, the angiosperm-sourced aromatic triterpane shows a much larger CIE of 6‰ and suggests that angiosperms increased in their carbon isotopic fractionation during the PETM. Our results thus indicate that the 4.5‰ C 29n-alkane CIE reported previously represents the average CIE of conifers and angiosperms at this site and suggest that the large and variable CIE observed in terrestrial records may be partly explained by the variable contributions of conifers and angiosperms. The differential response in isotopic fractionation of angiosperms and conifers points to different physiological responses of these vegetation types to the rise in temperature, humidity, and greenhouse gases during the PETM.

  6. Heat transfer in fish: are short excursions between habitats a thermoregulatory behaviour to exploit resources in an unfavourable thermal environment?

    Science.gov (United States)

    Pépino, Marc; Goyer, Katerine; Magnan, Pierre

    2015-11-01

    Temperature is the primary environmental factor affecting physiological processes in ectotherms. Heat-transfer models describe how the fish's internal temperature responds to a fluctuating thermal environment. Specifically, the rate coefficient (k), defined as the instantaneous rate of change in body temperature in relation to the difference between ambient and body temperature, summarizes the combined effects of direct thermal conduction through body mass, passive convection (intracellular and intercellular fluids) and forced convective heat transfer (cardiovascular system). The k-coefficient is widely used in fish ecology to understand how body temperature responds to changes in water temperature. The main objective of this study was to estimate the k-coefficient of brook charr equipped with internal temperature-sensitive transmitters in controlled laboratory experiments. Fish were first transferred from acclimation tanks (10°C) to tanks at 14, 19 or 23°C (warming experiments) and were then returned to the acclimation tanks (10°C; cooling experiments), thus producing six step changes in ambient temperature. We used non-linear mixed models to estimate the k-coefficient. Model comparisons indicated that the model incorporating the k-coefficient as a function of absolute temperature difference (dT: 4, 9 and 13°C) best described body temperature change. By simulating body temperature in a heterogeneous thermal environment, we provide theoretical predictions of maximum excursion duration between feeding and resting areas. Our simulations suggest that short (i.e. behaviour adopted by cold freshwater fish species to sustain body temperature below a critical temperature threshold, enabling them to exploit resources in an unfavourable thermal environment. © 2015. Published by The Company of Biologists Ltd.

  7. Testing the ``Wildfire Hypothesis:'' Terrestrial Organic Carbon Burning as the Cause of the Paleocene-Eocene Boundary Carbon Isotope Excursion

    Science.gov (United States)

    Moore, E. A.; Kurtz, A. C.

    2005-12-01

    The 3‰ negative carbon isotope excursion (CIE) at the Paleocene-Eocene boundary has generally been attributed to dissociation of seafloor methane hydrates. We are testing the alternative hypothesis that the carbon cycle perturbation resulted from wildfires affecting the extensive peatlands and coal swamps formed in the Paleocene. Accounting for the CIE with terrestrial organic carbon rather than methane requires a significantly larger net release of fossil carbon to the ocean-atmosphere, which may be more consistent with the extreme global warming and ocean acidification characteristic of the Paleocene-Eocene Thermal Maximum (PETM). While other researchers have noted evidence of fires at the Paleocene-Eocene boundary in individual locations, the research presented here is designed to test the "wildfire hypothesis" for the Paleocene-Eocene boundary by examining marine sediments for evidence of a global increase in wildfire activity. Such fires would produce massive amounts of soot, widely distributed by wind and well preserved in marine sediments as refractory black carbon. We expect that global wildfires occurring at the Paleocene-Eocene boundary would produce a peak in black carbon abundance at the PETM horizon. We are using the method of Gelinas et al. (2001) to produce high-resolution concentration profiles of black carbon across the Paleocene-Eocene boundary using seafloor sediments from ODP cores, beginning with the Bass River core from ODP leg 174AX and site 1209 from ODP leg 198. This method involves the chemical and thermal extraction of non-refractory carbon followed by combustion of the residual black carbon and measurement as CO2. Measurement of the δ 13C of the black carbon will put additional constraints on the source of the organic material combusted, and will allow us to determine if this organic material was formed prior to or during the CIE.

  8. Development and validation of a protocol for field validation of passive dosimeters for ethylene oxide excursion limit monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Puskar, M.A.; Szopinski, F.G.; Hecker, L.H. (Corporate Industrial Hygiene Laboratory, Abbott Laboratories, North Chicago, IL (USA))

    1991-04-01

    An exposure and analysis protocol is described for the field validation of passive dosimeters for ethylene oxide (EtO) excursion limit monitoring. The protocol calls for the use of a field exposure chamber with concurrent sampling using Tedlar air-sampling bags. The bags are analyzed immediately after sampling by gas chromatography with flame ionization detection (GC-FID). The chamber design allows all monitors to be exposed for the exact same time in the field. The sampling and analysis procedure not only determines the actual concentration of EtO present during the monitor's exposure but estimates if concentrations of EtO vary from point to point in the monitor array during the exposure. In chamber operation, the accuracy of the standard generator used to calibrate the GC-FID was independently verified in the field by the standard additions method. The sampling bias of the sampling train was determined to be -3.5% in the 2.4 ppm to 14.3 ppm concentration range. To estimate the stability of collected EtO samples in Tedlar bags, the rate of EtO loss in the bags was determined to be 0.011 ppm/hr at 2.57 ppm and 0.066 ppm/hr at 8.07 ppm. Sampling bias of the passive methods by additional EtO exposure of the monitors in the closed chamber after sampling and during purging was determined to be +1.5%. The Tedlar bag sampling method with subsequent GC-FID determination demonstrated a coefficient of variation of 1.8% at 2.43 ppm.

  9. THE ROLE OF FOLK ARTS AND CRAFTS OF DAGESTAN IN CONSOLIDATING AND EXPANDING THE TOURIST-EXCURSION ROUTES

    Directory of Open Access Journals (Sweden)

    G. G. Gazimagomedov

    2017-01-01

    Full Text Available Aim. The aim of this study is to create and represent the tourist routes in the places of the traditional folk arts and crafts in the Republic of Dagestan.Research Methodology. In the first stage of the study, according to the register and public materials we identified and studied traditional places of folk arts and crafts; carried out monitoring of existing tourist routes and programs. Developed routes are included in the tourist route map.Findings and discussion. We developed five radial exit routes from the city of Makhachkala, characteristics of which are presented below. Folk arts and crafts of Dagestan are a unique part of the artistic culture and at the same time, it is a branch of industry with a high level of tourist attractiveness. Today, Dagestan is one of the few areas in the modern world where traditional folk art is naturally a part of a contemporary social life having the rights of the dominant cultural unity due to the peculiarities of its historical development. Archaeological studies show that due to the geographical position, in Dagestan, there has been an interaction of significant aspects of cultural phenomena relating to the ancient civilizations of the Mediterranean, Western, Central and Eastern Europe, on the one hand, and the development of cultures of different regions of Asia, on the other hand. Coupled with the traditions of the ancient population of the Caucasus, they formed complex and varied artistic conglomerate.Conclusion. The study revealed the basic centers of traditional arts and crafts of the Republic of Dagestan, hiving a high tourism potential. On this basis, we developed five tourist-excursion routes. These routes are included in the information booklet, which has a marketing and information value. 

  10. Accurate Predictions of Mean Geomagnetic Dipole Excursion and Reversal Frequencies, Mean Paleomagnetic Field Intensity, and the Radius of Earth's Core Using McLeod's Rule

    Science.gov (United States)

    Voorhies, Coerte V.; Conrad, Joy

    1996-01-01

    The geomagnetic spatial power spectrum R(sub n)(r) is the mean square magnetic induction represented by degree n spherical harmonic coefficients of the internal scalar potential averaged over the geocentric sphere of radius r. McLeod's Rule for the magnetic field generated by Earth's core geodynamo says that the expected core surface power spectrum (R(sub nc)(c)) is inversely proportional to (2n + 1) for 1 less than n less than or equal to N(sub E). McLeod's Rule is verified by locating Earth's core with main field models of Magsat data; the estimated core radius of 3485 kn is close to the seismologic value for c of 3480 km. McLeod's Rule and similar forms are then calibrated with the model values of R(sub n) for 3 less than or = n less than or = 12. Extrapolation to the degree 1 dipole predicts the expectation value of Earth's dipole moment to be about 5.89 x 10(exp 22) Am(exp 2)rms (74.5% of the 1980 value) and the expected geomagnetic intensity to be about 35.6 (mu)T rms at Earth's surface. Archeo- and paleomagnetic field intensity data show these and related predictions to be reasonably accurate. The probability distribution chi(exp 2) with 2n+1 degrees of freedom is assigned to (2n + 1)R(sub nc)/(R(sub nc). Extending this to the dipole implies that an exceptionally weak absolute dipole moment (less than or = 20% of the 1980 value) will exist during 2.5% of geologic time. The mean duration for such major geomagnetic dipole power excursions, one quarter of which feature durable axial dipole reversal, is estimated from the modern dipole power time-scale and the statistical model of excursions. The resulting mean excursion duration of 2767 years forces us to predict an average of 9.04 excursions per million years, 2.26 axial dipole reversals per million years, and a mean reversal duration of 5533 years. Paleomagnetic data show these predictions to be quite accurate. McLeod's Rule led to accurate predictions of Earth's core radius, mean paleomagnetic field

  11. Assessment of myocardial bridge by cardiac CT: Intracoronary transluminal attenuation gradient derived from diastolic phase predicts systolic compression

    Energy Technology Data Exchange (ETDEWEB)

    Yu, Meng Meng; Zhang, Yang; Li, Yue Hua; Li, Wen Bin; Li, Ming Hua; Zhang, Jiayin [Institute of Diagnostic and Interventional Radiology, Shanghai Jiao Tong University Affiliated Sixth People' s Hospital, Shangha (China)

    2017-08-01

    To study the predictive value of transluminal attenuation gradient (TAG) derived from diastolic phase of coronary computed tomography angiography (CCTA) for identifying systolic compression of myocardial bridge (MB). Consecutive patients diagnosed with MB based on CCTA findings and without obstructive coronary artery disease were retrospectively enrolled. In total, 143 patients with 144 MBs were included in the study. Patients were classified into three groups: without systolic compression, with systolic compression < 50%, and with systolic compression ≥ 50%. TAG was defined as the linear regression coefficient between intraluminal attenuation in Hounsfield units (HU) and length from the vessel ostium. Other indices such as the length and depth of the MB were also recorded. TAG was the lowest in MB patients with systolic compression ≥ 50% (-19.9 ± 8.7 HU/10 mm). Receiver operating characteristic curve analysis was performed to determine the optimal cutoff values for identifying systolic compression ≥ 50%. The result indicated an optimal cutoff value of TAG as -18.8 HU/10 mm (area under curve = 0.778, p < 0.001), which yielded higher sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy (54.1, 80.5, 72.8, and 75.0%, respectively). In addition, the TAG of MB with diastolic compression was significantly lower than the TAG of MB without diastolic compression (-21.4 ± 4.8 HU/10 mm vs. -12.7 ± 8 HU/10 mm, p < 0.001). TAG was a better predictor of MB with systolic compression ≥ 50%, compared to the length or depth of the MB. The TAG of MB with persistent diastolic compression was significantly lower than the TAG without diastolic compression.

  12. Experience as Excursion

    DEFF Research Database (Denmark)

    Svabo, Connie; Shanks, Michael

    2014-01-01

    researchers and practitioners to travel – making it possible to follow experiences as they are enacted across and between places, modes of transportation, mobile mediation and assemblages of things. Drawing on the nomadic metaphysics of philosopher Michel Serres, the journeying, shifting and propagating...... qualities of experience are highlighted as part of a suggestion that design may indeed relate as much to metaphysics as to mechanics, materials science, and the psychology of the consumer and user. An Experience Design is sketched out as the choreography of temporary and shifting engagements across...

  13. Excursions through KK modes

    Energy Technology Data Exchange (ETDEWEB)

    Furuuchi, Kazuyuki [Manipal Centre for Natural Sciences, Manipal University,Manipal, Karnataka 576104 (India)

    2016-07-07

    In this article we study Kaluza-Klein (KK) dimensional reduction of massive Abelian gauge theories with charged matter fields on a circle. Since local gauge transformations change position dependence of the charged fields, the decomposition of the charged matter fields into KK modes is gauge dependent. While whole KK mass spectrum is independent of the gauge choice, the mode number depends on the gauge. The masses of the KK modes also depend on the field value of the zero-mode of the extra dimensional component of the gauge field. In particular, one of the KK modes in the KK tower of each massless 5D charged field becomes massless at particular values of the extra-dimensional component of the gauge field. When the extra-dimensional component of the gauge field is identified with the inflaton, this structure leads to recursive cosmological particle productions.

  14. Excursions through KK modes

    International Nuclear Information System (INIS)

    Furuuchi, Kazuyuki

    2016-01-01

    In this article we study Kaluza-Klein (KK) dimensional reduction of massive Abelian gauge theories with charged matter fields on a circle. Since local gauge transformations change position dependence of the charged fields, the decomposition of the charged matter fields into KK modes is gauge dependent. While whole KK mass spectrum is independent of the gauge choice, the mode number depends on the gauge. The masses of the KK modes also depend on the field value of the zero-mode of the extra dimensional component of the gauge field. In particular, one of the KK modes in the KK tower of each massless 5D charged field becomes massless at particular values of the extra-dimensional component of the gauge field. When the extra-dimensional component of the gauge field is identified with the inflaton, this structure leads to recursive cosmological particle productions.

  15. A Scientific Excursion: Volcanoes.

    Science.gov (United States)

    Olds, Henry, Jr.

    1983-01-01

    Reviews an educationally valuable and reasonably well-designed simulation of volcanic activity in an imaginary land. VOLCANOES creates an excellent context for learning information about volcanoes and for developing skills and practicing methods needed to study behavior of volcanoes. (Author/JN)

  16. Recruitment strategies and challenges in a large intervention trial: Systolic Blood Pressure Intervention Trial (SPRINT)

    Science.gov (United States)

    Ramsey, Thomas M; Snyder, Joni K; Lovato, Laura C; Roumie, Christianne L; Glasser, Steven P; Cosgrove, Nora M; Olney, Christine M; Tang, Rocky H; Johnson, Karen C; Still, Carolyn H; Gren, Lisa H; Childs, Jeffery C; Crago, Osa L; Summerson, John H; Walsh, Sandy M; Perdue, Letitia H; Bankowski, Denise M; Goff, David C

    2016-01-01

    Background The Systolic Blood Pressure Intervention Trial (SPRINT) is a multicenter, randomized clinical trial of 9,361 participants with hypertension who are ≥ 50 years old. The trial is designed to evaluate the effect of intensive systolic blood pressure control (systolic blood pressure goal recruitment strategies and lessons learned during recruitment of the SPRINT cohort and five targeted participant subgroups: pre-existing cardiovascular disease, pre-existing chronic kidney disease, age ≥ 75 years, women, and minorities. Methods In collaboration with the National Institutes of Health Project Office and SPRINT Coordinating Center, five Clinical Center Networks oversaw clinical site selection, recruitment, and trial activities. Recruitment began November 8, 2010 and ended March 15, 2013 (about 28 months). Various recruitment strategies were used, including mass mailing, brochures, referrals from healthcare providers or friends, posters, newspaper ads, radio ads, and electronic medical record searches. Results Recruitment was scheduled to last 24 months to enroll a target of 9,250 participants; in just over 28 months, the trial enrolled 9,361 participants. The trial screened 14,692 volunteers, with 33% of initial screens originating from the use of mass mailing lists. Screening results show that participants also responded to recruitment efforts through referral by SPRINT staff, healthcare providers, or friends (45%); brochures or posters placed in clinic waiting areas (15%); and television, radio, newspaper, internet ads, or toll-free numbers (8%). The overall recruitment yield (number randomized /number screened) was 64% (9,361 randomized /14,692 screened), 77% for those with cardiovascular disease, 79% for those with chronic kidney disease, 70% for those age ≥ 75 years, 55% for women, and 61% for minorities. As recruitment was observed to lag behind expectations, additional clinics were included and inclusion criteria were broadened, keeping event rates

  17. Complex Association of Sex Hormones on Left Ventricular Systolic Function: Insight into Sexual Dimorphism.

    Science.gov (United States)

    Salem, Joe-Elie; Nguyen, Lee S; Hammoudi, Nadjib; Preud'homme, Gisèle; Hulot, Jean-Sebastien; Leban, Monique; Funck-Brentano, Christian; Touraine, Philippe; Isnard, Richard; Bachelot, Anne

    2018-02-01

    Normal values of left ventricular ejection fraction (LVEF) and absolute values of global longitudinal strain (GLS) are lower in men than in women. Data concerning the association of sex hormone levels on these left ventricular systolic function surrogates are scarce. The aim of this study was to determine the association of sex hormones with systolic left ventricular function in healthy subjects and patients with congenital adrenal hyperplasia (CAH) as a model of testosterone dysregulation. Eighty-four adult patients with CAH (58 women; median age, 27 years; interquartile range, 23-36 years) and 84 healthy subjects matched for sex and age were prospectively included. Circulating concentrations of sex hormones were measured within 48 hours of echocardiography with assessment of LVEF and left ventricular longitudinal, radial, and circumferential strain. LVEF and GLS were higher in healthy women than in healthy men (63.9 ± 4.2% vs 60.9 ± 5.1% [P interquartile range, 0.04-0.14 ng/mL] vs 0.16 ng/mL [interquartile range, 0.04-0.3 ng/mL], P interquartile range, 1.3-3 ng/mL] vs 2.9 ng/mL [interquartile range, 2.5-3.4 ng/mL], P < .05). In men, LVEF and GLS were negatively correlated with bioavailable testosterone levels (r = -0.3, P ≤ .05, and r = -0.45, P < .01, respectively), while midventricular radial strain was positively correlated with bioavailable testosterone level (r = 0.38, P < .05). The absolute value of circumferential strain was positively correlated with follicle-stimulating hormone (r = 0.65, P < .0001). These data support that the existence of sex dimorphism concerning left ventricular systolic cardiac function is significantly associated with testosterone levels. Copyright © 2017 American Society of Echocardiography. Published by Elsevier Inc. All rights reserved.

  18. Multi-planed unified switching topologies

    Science.gov (United States)

    Chen, Dong; Heidelberger, Philip; Sugawara, Yutaka

    2017-07-04

    An apparatus and method for extending the scalability and improving the partitionability of networks that contain all-to-all links for transporting packet traffic from a source endpoint to a destination endpoint with low per-endpoint (per-server) cost and a small number of hops. An all-to-all wiring in the baseline topology is decomposed into smaller all-to-all components in which each smaller all-to-all connection is replaced with star topology by using global switches. Stacking multiple copies of the star topology baseline network creates a multi-planed switching topology for transporting packet traffic. Point-to-point unified stacking method using global switch wiring methods connects multiple planes of a baseline topology by using the global switches to create a large network size with a low number of hops, i.e., low network latency. Grouped unified stacking method increases the scalability (network size) of a stacked topology.

  19. Suicide plane crash against nuclear power plants

    International Nuclear Information System (INIS)

    Richard, A.

    2002-01-01

    Cea (French atomic energy commission) and EDF (Electricity of France) are reassessing their safety standards concerning suicide plane attacks against nuclear facilities. The general idea is to study the non-linear behaviour of reinforced concrete in case of mechanical impact. American studies carried out in 1988 show that a F-14 phantom crashing into a 3,6 meter thick wall at a speed of 774 km/h penetrates only the first 5 cm of the wall. More recent studies performed in Germany and based on computerized simulations show that the reactor containment can sustain impacts from a F15 plane or even from a 747-Boeing but contiguous buildings like the one which houses spent fuels might be more easily damaged because of their metal roofing. (A.C.)

  20. A multiplicity jump trigger using silicon planes

    International Nuclear Information System (INIS)

    Alexopoulos, T.; Erwin, A.R.

    1993-01-01

    Since silicon tracking planes are already present in a B decay experiment, it is an attractive idea to use these as part of a multiplicity jump detector. Two average B decays would produce a multiplicity jump of around 10 in the final state. Such a trigger has been tried for a fixed target Charm experiment with disappointing success. The failure was attributed to the difficulty in adequately controlling the gains of a large number of microstrip amplifies

  1. Wafer plane inspection for advanced reticle defects

    Science.gov (United States)

    Nagpal, Rajesh; Ghadiali, Firoz; Kim, Jun; Huang, Tracy; Pang, Song

    2008-05-01

    Readiness of new mask defect inspection technology is one of the key enablers for insertion & transition of the next generation technology from development into production. High volume production in mask shops and wafer fabs demands a reticle inspection system with superior sensitivity complemented by a low false defect rate to ensure fast turnaround of reticle repair and defect disposition (W. Chou et al 2007). Wafer Plane Inspection (WPI) is a novel approach to mask defect inspection, complementing the high resolution inspection capabilities of the TeraScanHR defect inspection system. WPI is accomplished by using the high resolution mask images to construct a physical mask model (D. Pettibone et al 1999). This mask model is then used to create the mask image in the wafer aerial plane. A threshold model is applied to enhance the inspectability of printing defects. WPI can eliminate the mask restrictions imposed on OPC solutions by inspection tool limitations in the past. Historically, minimum image restrictions were required to avoid nuisance inspection stops and/or subsequent loss of sensitivity to defects. WPI has the potential to eliminate these limitations by moving the mask defect inspections to the wafer plane. This paper outlines Wafer Plane Inspection technology, and explores the application of this technology to advanced reticle inspection. A total of twelve representative critical layers were inspected using WPI die-to-die mode. The results from scanning these advanced reticles have shown that applying WPI with a pixel size of 90nm (WPI P90) captures all the defects of interest (DOI) with low false defect detection rates. In validating CD predictions, the delta CDs from WPI are compared against Aerial Imaging Measurement System (AIMS), where a good correlation is established between WPI and AIMSTM.

  2. Cues for localization in the horizontal plane

    DEFF Research Database (Denmark)

    Jeppesen, Jakob; Møller, Henrik

    2005-01-01

    Spatial localization of sound is often described as unconscious evaluation of cues given by the interaural time difference (ITD) and the spectral information of the sound that reaches the two ears. Our present knowledge suggests the hypothesis that the ITD roughly determines the cone of the perce...... independently in HRTFs used for binaural synthesis. The ITD seems to be dominant for localization in the horizontal plane even when the spectral information is severely degraded....

  3. Resonant power processors. I - State plane analysis

    Science.gov (United States)

    Oruganti, R.; Lee, F. C.

    1984-01-01

    State-plane techniques in conjunction with piecewise-linear analysis is employed to study the steady-state and transient characteristics of a series resonant converter. With the direct viewing of the resonant tank energy and the device switching instants, the state portrayal provides unique insights into the complex behavior of the converter. Operation of the converter under both continuous and discontinuous current modes and at frequencies both below and above resonant frequency are discussed.

  4. The Off-plane Grating Rocket Experiment

    Science.gov (United States)

    Donovan, Benjamin

    2018-01-01

    The next generation of X-ray spectrometers necessitate significant increases in both resolution and effective area to achieve the science goals set forth in the 2010 Decadal Survey and the 2013 Astrophysics Roadmap. The Off-plane Grating Rocket Experiment (OGRE), an X-ray spectroscopy suborbital rocket payload currently scheduled for launch in Q3 2020, will serve as a testbed for several key technologies which can help achieve the desired performance increases of future spectrometers. OGRE will be the first instrument to fly mono-crystalline silicon X-ray mirrors developed at NASA Goddard Space Flight Center. The payload will also utilize an array of off-plane gratings manufactured at The Pennsylvania State University. Additionally, the focal plane will be populated with an array of four electron-multiplying CCDs developed by the Open University and XCAM Ltd. With these key technologies, OGRE hopes to achieve the highest resolution on-sky soft X-ray spectrum to date. We discuss the optical design, expected performance, and the current status of the payload.

  5. Blackfolds, plane waves and minimal surfaces

    Energy Technology Data Exchange (ETDEWEB)

    Armas, Jay [Physique Théorique et Mathématique, Université Libre de Bruxelles and International Solvay Institutes, ULB-Campus Plaine CP231, B-1050 Brussels (Belgium); Albert Einstein Center for Fundamental Physics, University of Bern,Sidlerstrasse 5, 3012 Bern (Switzerland); Blau, Matthias [Albert Einstein Center for Fundamental Physics, University of Bern,Sidlerstrasse 5, 3012 Bern (Switzerland)

    2015-07-29

    Minimal surfaces in Euclidean space provide examples of possible non-compact horizon geometries and topologies in asymptotically flat space-time. On the other hand, the existence of limiting surfaces in the space-time provides a simple mechanism for making these configurations compact. Limiting surfaces appear naturally in a given space-time by making minimal surfaces rotate but they are also inherent to plane wave or de Sitter space-times in which case minimal surfaces can be static and compact. We use the blackfold approach in order to scan for possible black hole horizon geometries and topologies in asymptotically flat, plane wave and de Sitter space-times. In the process we uncover several new configurations, such as black helicoids and catenoids, some of which have an asymptotically flat counterpart. In particular, we find that the ultraspinning regime of singly-spinning Myers-Perry black holes, described in terms of the simplest minimal surface (the plane), can be obtained as a limit of a black helicoid, suggesting that these two families of black holes are connected. We also show that minimal surfaces embedded in spheres rather than Euclidean space can be used to construct static compact horizons in asymptotically de Sitter space-times.

  6. Focal plane scanner with reciprocating spatial window

    Science.gov (United States)

    Mao, Chengye (Inventor)

    2000-01-01

    A focal plane scanner having a front objective lens, a spatial window for selectively passing a portion of the image therethrough, and a CCD array for receiving the passed portion of the image. All embodiments have a common feature whereby the spatial window and CCD array are mounted for simultaneous relative reciprocating movement with respect to the front objective lens, and the spatial window is mounted within the focal plane of the front objective. In a first embodiment, the spatial window is a slit and the CCD array is one-dimensional, and successive rows of the image in the focal plane of the front objective lens are passed to the CCD array by an image relay lens interposed between the slit and the CCD array. In a second embodiment, the spatial window is a slit, the CCD array is two-dimensional, and a prism-grating-prism optical spectrometer is interposed between the slit and the CCD array so as to cause the scanned row to be split into a plurality of spectral separations onto the CCD array. In a third embodiment, the CCD array is two-dimensional and the spatial window is a rectangular linear variable filter (LVF) window, so as to cause the scanned rows impinging on the LVF to be bandpass filtered into spectral components onto the CCD array through an image relay lens interposed between the LVF and the CCD array.

  7. Blackfolds, plane waves and minimal surfaces

    Science.gov (United States)

    Armas, Jay; Blau, Matthias

    2015-07-01

    Minimal surfaces in Euclidean space provide examples of possible non-compact horizon geometries and topologies in asymptotically flat space-time. On the other hand, the existence of limiting surfaces in the space-time provides a simple mechanism for making these configurations compact. Limiting surfaces appear naturally in a given space-time by making minimal surfaces rotate but they are also inherent to plane wave or de Sitter space-times in which case minimal surfaces can be static and compact. We use the blackfold approach in order to scan for possible black hole horizon geometries and topologies in asymptotically flat, plane wave and de Sitter space-times. In the process we uncover several new configurations, such as black helicoids and catenoids, some of which have an asymptotically flat counterpart. In particular, we find that the ultraspinning regime of singly-spinning Myers-Perry black holes, described in terms of the simplest minimal surface (the plane), can be obtained as a limit of a black helicoid, suggesting that these two families of black holes are connected. We also show that minimal surfaces embedded in spheres rather than Euclidean space can be used to construct static compact horizons in asymptotically de Sitter space-times.

  8. Linearized motion estimation for articulated planes.

    Science.gov (United States)

    Datta, Ankur; Sheikh, Yaser; Kanade, Takeo

    2011-04-01

    In this paper, we describe the explicit application of articulation constraints for estimating the motion of a system of articulated planes. We relate articulations to the relative homography between planes and show that these articulations translate into linearized equality constraints on a linear least-squares system, which can be solved efficiently using a Karush-Kuhn-Tucker system. The articulation constraints can be applied for both gradient-based and feature-based motion estimation algorithms and to illustrate this, we describe a gradient-based motion estimation algorithm for an affine camera and a feature-based motion estimation algorithm for a projective camera that explicitly enforces articulation constraints. We show that explicit application of articulation constraints leads to numerically stable estimates of motion. The simultaneous computation of motion estimates for all of the articulated planes in a scene allows us to handle scene areas where there is limited texture information and areas that leave the field of view. Our results demonstrate the wide applicability of the algorithm in a variety of challenging real-world cases such as human body tracking, motion estimation of rigid, piecewise planar scenes, and motion estimation of triangulated meshes.

  9. Comparison of frequencies of left ventricular systolic and diastolic heart failure in Chinese living in Hong Kong.

    Science.gov (United States)

    Yip, G W; Ho, P P; Woo, K S; Sanderson, J E

    1999-09-01

    There is a wide variation (13% to 74%) in the reported prevalence of heart failure associated with normal left ventricular (LV) systolic function (diastolic heart failure). There is no published information on this condition in China. To ascertain the prevalence of diastolic heart failure in this community, 200 consecutive patients with the typical features of congestive heart failure were studied with standard 2-dimensional Doppler echocardiography. A LV ejection fraction (LVEF) >45% was considered normal. The results showed that 12.5% had significant valvular heart disease. Of the remaining 175 patients, 132 had a LVEF >45% (75%). Therefore, 66% of patients with a clinical diagnosis of heart failure had a normal LVEF. Heart failure with normal LV systolic function was more common than systolic heart failure in those >70 years old (65% vs 47%; p = 0.015). Most (57%) had an abnormal relaxation pattern in diastole and 14% had a restrictive filling pattern. In the systolic heart failure group, a restrictive filling pattern was more common (46%). There were no significant differences in the sex distribution, etiology, or prevalence of LV hypertrophy between these 2 heart failure groups. In conclusion, heart failure with a normal LVEF or diastolic heart failure is more common than systolic heart failure in Chinese patients with the symptoms of heart failure. This may be related to older age at presentation and the high prevalence of hypertension in this community.

  10. The correlation between psychological intervention and heart rate,systolic pressure in patients of cervical cancer treated with interventional chemoembolization

    International Nuclear Information System (INIS)

    Qiao Cuiyun; Lan Guiyun; Liu Shuang; Chen Bao'e; Liu Yali; Wang Zhujun

    2010-01-01

    Objective: To discuss the effect of psychological intervention on the heart rate, systolic pressure of the patients with cervical cancer who are treated with interventional chemoembolization. Methods: Eighty patients with cervical cancer were randomly and equally divided into two groups. Transcatheter arterial chemoembolization (TACE) was performed in all cases. Patients in study group (n=10) received systemic psychological intervention 30 minutes before TACE. The heart rate and systolic pressure of the patients were measured when TACE started. The results were compared with that obtained at the time of admission. Patients in control group (n=10) did not receive systemic psychological intervention before TACE and their heart rate and systolic pressure were measured in the same way as in study group. Results: At the time TACE started the heart rate and systolic pressure of the patients in study group were significantly lower than that in control group (P < 0.05). Conclusion: Preoperative psychological intervention is very helpful for reducing psychological stress and mental tension,in stabilizing heart rate and systolic pressure of the patients with cervical cancer who are treated with TACE. (authors)

  11. Use of different types of angiotensin converting enzyme inhibitors and mortality in systolic heart failure

    DEFF Research Database (Denmark)

    Svanström, Henrik; Pasternak, Björn; Melbye, Mads

    2015-01-01

    BACKGROUND: Angiotensin converting enzyme-inhibitors (ACEIs) are the first-line treatment for patients with heart failure (HF) with reduced ejection fraction (EF). The benefit of ACEIs in HF is regarded as a class effect and different types of agents are used interchangeably. However, evidence......-2012, were identified using the Danish HF Registry. New users of enalapril (n=1807), perindopril (n=1064), ramipril (n=3270), or trandolapril (n=1150), who started treatment within 60days of first-time hospital diagnosis of HF, were selected for inclusion. Subgroup analyses were conducted by sex, age, NYHA...... with ramipril. No significant differences were observed in subgroup analyses. CONCLUSIONS: These findings suggest equal effect of different types of ACEIs on mortality in systolic HF....

  12. 2014 Hypertension Guideline: Recommendation for a Change in Goal Systolic Blood Pressure

    Science.gov (United States)

    Handler, Joel

    2015-01-01

    The 2014 Kaiser Permanente Care Management Institute National Hypertension Guideline was developed to assist primary care physicians and other health care professionals in the outpatient treatment of uncomplicated hypertension in adult men and nonpregnant women aged 18 years and older. The new guideline reflects general acceptance, with minor modifications, of the “Evidence-Based Guideline” report by the panel members appointed to the National Heart, Lung, and Blood Institute 8th Joint National Committee. A major practice change is the recommendation for goal systolic blood pressure less than 150 mmHg in patients aged 60 years and older who are treated for hypertension in the absence of diabetes or chronic kidney disease. This article describes the reasons for, evidence for, and consequences of the change, and is followed by the National Guidelines handout. PMID:26057683

  13. Life course path analysis of birth weight, childhood growth, and adult systolic blood pressure

    DEFF Research Database (Denmark)

    Gamborg, Michael; Andersen, Per Kragh; Baker, Jennifer L

    2009-01-01

    body size, and thereby the total effect, of size and changes in size on later outcomes. Using data on childhood body size and adult systolic blood pressure from a sample of 1,284 Danish men born between 1936 and 1970, the authors compared results from path analysis with results from 3 standard...... regression methods. Path analysis produced easily interpretable results, and compared with standard regression methods it produced a noteworthy gain in statistical power. The effect of change in relative body size on adult blood pressure was more pronounced after age 11 years than in earlier childhood....... These results suggest that increases in body size prior to age 11 years are less harmful to adult blood pressure than increases occurring after this age....

  14. [Major tricuspid insufficiency and absence of systolic valvular coaptation. Echocardiographic study. Apropos of 6 cases].

    Science.gov (United States)

    Roudaut, R; Héraudeau, A; Gosse, P; Aouizerate, E; Dequecker, J L; Dallocchio, M

    1986-09-01

    In a retrospective series of 960 cases of tricuspid regurgitation studied by two-dimensional echocardiography 6 patients presented a systolic defect of valvular coaptation. The origin of this defect varied: one case was due to carcinoid, two to rheumatic cardiopathy, two to papyraceous right ventricle and one to sclerodermia associated with pulmonary arterial hypertension. The mechanism of the lacking coaptation varies according to the etiology: valvular retraction in carcinoid cardiopathy, right-ventricle dilatation, dilatation of the tricuspid ring and altered kinetics of the right ventricle in the other cases. Changed contractility of the right ventricle is the only element allowing to distinguish tricuspid regurgitation with and without a coaptation defect. Clinically this abnormality always points to an advanced stage of severe tricuspid regurgitation.

  15. New and emerging biomarkers in left ventricular systolic dysfunction--insight into dilated cardiomyopathy.

    Science.gov (United States)

    Gopal, Deepa M; Sam, Flora

    2013-08-01

    Dilated cardiomyopathy (DCM) is characterized by deteriorating cardiac performance, impaired contraction and dilation of the left ventricle (or both ventricles). Blood markers--known as "biomarkers"--allow insight into underlying pathophysiologic mechanisms and biologic pathways while predicting outcomes and guiding heart failure management and/or therapies. In this review, we provide an alternative approach to conceptualize heart failure biomarkers: the cardiomyocyte, its surrounding microenvironment, and the macroenvironment, integrating these entities which may impact cellular processes involved in the pathogenesis and/or propagation of DCM. Newer biomarkers of left ventricular systolic dysfunction can be categorized under: (a) myocyte stress and stretch, (b) myocyte apoptosis, (c) cardiac interstitium, (d) inflammation, (e) oxidative stress, (f) cardiac energetics, (g) neurohormones, and (h) renal biomarkers. Biomarkers provide insight into the pathogenesis of DCM while predicting and potentially providing prognostic information in these patients with heart failure.

  16. New and Emerging Biomarkers in Left Ventricular Systolic Dysfunction - Insight into Dilated Cardiomyopathy

    Science.gov (United States)

    Gopal, Deepa M.; Sam, Flora

    2013-01-01

    Background Dilated cardiomyopathy (DCM) is characterized by deteriorating cardiac performance and impaired contraction and dilation of the left (or both) ventricles. Blood markers – known as “biomarkers” allow insight into underlying pathophysiologic mechanisms and biologic pathways, while predicting outcomes and guiding heart failure management and/or therapies. Content In this review, we provide an alternative approach to conceptualize heart failure biomarkers: the cardiomyocyte, its surrounding microenvironment, and the macroenvironment with clear interaction between these entities which may impact cellular processes involved in the pathogenesis and/or propagation of DCM. Newer biomarkers of left ventricular systolic dysfunction can be categorized under: (a) myocyte stress and stretch, (b) myocyte apoptosis, (c) cardiac interstitium, (d) inflammation, (e) oxidative stress, (f) cardiac energetics, (g) neurohormones and (h) renal biomarkers. Summary Biomarkers provide insight into the pathogenesis of DCM while predicting and potentially providing prognostic information in these patients with heart failure. PMID:23609585

  17. Quantitative assessment of left ventricular systolic wall thickening using multidetector computed tomography

    DEFF Research Database (Denmark)

    Kristensen, Thomas S; Kofoed, Klaus F; Møller, Daniel V

    2009-01-01

    BACKGROUND: Multidetector computed tomography (MDCT) of the heart provides both anatomical and functional information. The objective of this study was to evaluate the accuracy of quantitative assessment of left ventricular contractile function in relation to two-dimensional transthoracic echocard......BACKGROUND: Multidetector computed tomography (MDCT) of the heart provides both anatomical and functional information. The objective of this study was to evaluate the accuracy of quantitative assessment of left ventricular contractile function in relation to two-dimensional transthoracic...... echocardiography (TTE). MATERIALS AND METHODS: Sixty-four patients with known or suspected coronary artery disease underwent ECG-gated 64-slice MDCT and TTE. Regional left ventricular contractile function was measured by percent systolic wall thickening (SWT) in 16 myocardial segments using MDCT, and compared...

  18. Left ventricular systolic dysfunction after transcatheter closure of a large patent ductus arteriosus.

    Science.gov (United States)

    Galal, Mohammed Omar; Arfi, Muhammed Amin; Nicole, Sekarski; Payot, Maurice; Hussain, Arif; Qureshi, Shakeel

    2005-11-01

    A 12-year-old boy reported in outpatient department with history of shortness of breath and dyspnoea on moderate exertion. Physical examination was significant for bounding pulses and for a continuous murmur III/VI, best heard at the left upper sternal border. Echocardiography confirmed a large patent arterial duct with shortening fraction of 33%. He underwent successful transcatheter closure of the patent arterial, using Amplatzer duct occluder 12/10. Few hours later echocardiography revealed an unexpected, yet important depression of left ventricular systolic function with shortening fraction decreasing to 24% and then two weeks later decreasing further to 20%. At a follow-up after four months, he had improved clinically but left ventricular dysfunction still persisted with shortening fraction of 24%.

  19. Interankle systolic blood pressure difference and renal outcomes in patients with chronic kidney disease.

    Science.gov (United States)

    Chen, Szu-Chia; Tsai, Yi-Chun; Huang, Jiun-Chi; Lee, Su-Chu; Chang, Jer-Ming; Hwang, Shang-Jyh; Chen, Hung-Chun

    2016-05-01

    Interankle blood pressure (BP) difference has been associated with peripheral artery disease and adverse cardiovascular outcomes. However, the relationship between interankle BP difference and renal outcomes in chronic kidney disease (CKD) has never been evaluated. The purpose of this study was to determine whether interankle BP difference is associated with the rate of renal function decline and progression to renal end points in patients with stage 3-5 CKD. We enrolled 144 patients with CKD from one regional hospital. The BP in four limbs was simultaneously measured using an ABI-form device. The decline in renal function was evaluated using an estimated glomerular filtration rate (eGFR) slope. Rapid renal progression was defined as an eGFR slope < -3 mL/min per 1.73 m(2) per year. The renal end points were defined as ≥ 25% decline in eGFR or commencement of dialysis during the follow-up period. During a mean follow-up period of 3.1 years, 90 patients (62.5%) reached renal end points. Multivariate analysis showed that an increased interankle systolic BP difference (per 5 mmHg) was associated with a worse eGFR slope (regression β, -0.292; 95% confidence interval [CI], -0.482 to -0.102; P = 0.003), rapid renal progression (odds ratio, 1.189; 95% CI, 1.015-1.394; P = 0.032), and an increased risk of progression to renal end points (hazard ratio, 1.126; 95% CI, 1.052-1.204, P = 0.001). Interankle systolic BP difference was associated with rapid renal progression and progression to renal end points in patients with stage 3-5 CKD in our study. © 2015 Asian Pacific Society of Nephrology.

  20. Psychological gender of men with systolic heart failure: a neglected strategy to cope with the disease?

    Science.gov (United States)

    Makowska, Agata; Rydlewska, Agnieszka; Krakowiak, Bartosz; Kuczyłska, Alicja; Sorokowski, Piotr; Danel, Dariusz; Pawłowski, Bogusław; Banasiak, Waldemar; Ponikowski, Piotr; Jankowska, Ewa A

    2014-05-01

    Diminished exercise capacity is a fundamental symptom of heart failure (HF), which is particularly disadvantageous for men for whom exercise capacity contributes significantly to their gender identity, self-esteem, and quality of life. In this study, we aimed to examine whether psychological gender would be different in men with systolic HF as compared with their healthy peers. The authors examined 48 men with systolic HF (age = 64 ± 10 years; body mass index = 28.3 ± 3.4 kg/m(2); NYHA I/II/III [%] = 25/65/10; left ventricular ejection fraction [LVEF] = 32.1 ± 7.8%) and 15 age-matched healthy men. Based on the results of the Polish version of the Bem Sex Role Inventory, the examined men were divided into four types of psychological gender: "masculine" (M), "feminine" (F), "unspecified" (U), and "androgynous" (A). None of the men with HF presented M type of psychological gender, whereas this type was found in 27% of the healthy men (p = .0002). The prevalence of both A (38% vs. 47%) and F (10% vs. 20%, both p > .05) types of psychological gender was similar between men with HF versus without HF. More men with HF fulfilled the criteria of the U type of psychological gender as compared with healthy peers (51% vs. 7%, p = .002). Men with HF and the F type of psychological gender were treated with spironolactone more frequently than those classified with the U and A types (both p masculine" and the overrepresentation of "psychologically unspecified" gender types in the HF group suggests that psychological gender may be affected among men with HF.

  1. Measuring systolic arterial blood pressure. Possible errors from extension tubes or disposable transducer domes.

    Science.gov (United States)

    Rothe, C F; Kim, K C

    1980-11-01

    The purpose of this study was to evaluate the magnitude of possible error in the measurement of systolic blood pressure if disposable, built-in diaphragm, transducer domes or long extension tubes between the patient and pressure transducer are used. Sinusoidal or arterial pressure patterns were generated with specially designed equipment. With a long extension tube or trapped air bubbles, the resonant frequency of the catheter system was reduced so that the arterial pulse was amplified as it acted on the transducer and, thus, gave an erroneously high systolic pressure measurement. The authors found this error to be as much as 20 mm Hg. Trapped air bubbles, not stopcocks or connections, per se, lead to poor fidelity. The utility of a continuous catheter flush system (Sorenson, Intraflow) to estimate the resonant frequency and degree of damping of a catheter-transducer system is described, as are possibly erroneous conclusions. Given a rough estimate of the resonant frequency of a catheter-transducer system and the magnitude of overshoot in response to a pulse, the authors present a table to predict the magnitude of probable error. These studies confirm the variability and unreliability of static calibration that may occur using some safety diaphragm domes and show that the system frequency response is decreased if air bubbles are trapped between the diaphragms. The authors conclude that regular procedures should be established to evaluate the accuracy of the pressure measuring systems in use, the transducer should be placed as close to the patient as possible, the air bubbles should be assiduously eliminated from the system.

  2. Validity of Some Anthropometric Indicators in the Prediction of High Systolic Blood Pressure among Indian Adolescents

    Directory of Open Access Journals (Sweden)

    Shobha Rao

    2008-01-01

    Full Text Available Background In view of the increasing prevalence of obesity in children, it is necessary to investigate the relative performance of different indicators used for its assessment and health consequences. Objectives To examine concordance between various indicators used for assessing obesity among adolescents and to examine their ability to predict risk of high systolic blood pressure. Design Cross-sectional study, from two schools catering to affluent class. Subjects Children in age 9–16 yr (n = 1146 boys and 1036 girls. Measurements Body weight, height, skinfold thickness at triceps (TSFT and body fat percent by trained investigators and blood pressure measurement by a pediatrician using sphygmomanometer. Results Prevalence of overweight was lowest with criterion of TSFT (11.7% in boys; 7.6% in girls and was highest using criterion of body fat percent (53.7% in boys and 28.4% in girls. Body mass index (BMI had high significant correlation with each of the indicator and with systolic blood pressure (SBP as well, in both sexes. All the indicators with conventional cut offs showed poor sensitivity for predicting high SBP. However, receiver operating characteristics (ROC cut-offs improved sensitivity considerably, but the values were much lower compared to conventional cut-offs. Conclusions There is considerable disparity in the estimates of overweight children obtained by different indicators. Lower values of ROC cut-offs highlights the need for population specific customized classification systems for assessing obesity in view of the probable population differences in relative risks of non-communicable adult diseases.

  3. Autonomic Predictors of Hospitalization Due to Heart Failure Decompensation in Patients with Left Ventricular Systolic Dysfunction.

    Directory of Open Access Journals (Sweden)

    Ludmiła Daniłowicz-Szymanowicz

    Full Text Available Autonomic nervous system balance can be significantly deteriorated during heart failure exacerbation. However, it is still unknown whether these changes are only the consequence of heart failure decompensation or can also predict development thereof. Objectives were to verify if simple, non-invasive autonomic parameters, such as baroreflex sensitivity and short-term heart rate variability can provide independent of other well-known clinical parameters information on the risk of heart failure decompensation in patients with left ventricular systolic dysfunction.In 142 stable patients with left ventricular ejection fraction ≤ 40%, baroreflex sensitivity and short-term heart rate variability, as well as other well-known clinical parameters, were analyzed. During 23 ± 9 months of follow-up 19 patients were hospitalized due to the heart failure decompensation (EVENT.Pre-specified cut-off values of baroreflex sensitivity (≤2.4 ms/mmHg and low frequency power index of heart rate variability (≤19 ms2 were significantly associated with the EVENTs (hazard ratio 4.43, 95% confidence interval [CI] 1.35-14.54 and 5.41, 95% CI 1.87-15.65 respectively. EVENTs were also associated with other parameters, such as left ventricular ejection fraction, NYHA class, diuretic use, renal function, brain natriuretic peptide and hemoglobin level, left atrial size, left and right ventricular heart failure signs. After adjusting baroreflex sensitivity and low frequency power index for each of the abovementioned parameters, autonomic parameters were still significant predictors of hospitalization due to the heart failure decompensation.Simple, noninvasive autonomic indices can be helpful in identifying individuals with increased risk of hospitalization due to the heart failure decompensation among clinically stable patients with left ventricular systolic dysfunction, even when adjusted for other well-known clinical parameters.

  4. IGF-1 Prevents Diastolic and Systolic Dysfunction Associated with Cardiomyopathy and Preserves Adrenergic Sensitivity

    Science.gov (United States)

    Roof, Steve R.; Boslett, James; Russell, Duncan; del Rio, Carlos; Alecusan, Joe; Zweier, Jay L.; Ziolo, Mark T.; Hamlin, Robert; Mohler, Peter J.; Curran, Jerry

    2015-01-01

    Aims Insulin-like growth factor 1 (IGF-1)-dependent signaling promotes exercise-induced physiological cardiac hypertrophy. However, the in vivo therapeutic potential of IGF-1 for heart disease is not well established. Here we test the potential therapeutic benefits of IGF-1 on cardiac function using an in vivo model of chronic catecholamine-induced cardiomyopathy. Methods Rats were perfused with isoproterenol via osmotic pump (1 mg/kg/day) and treated with 2 mg/kg IGF-1 (2 mg/kg/day, 6 days a week) for 2 or 4 weeks. Echocardiography, ECG, and blood pressure were assessed. In vivo pressure-volume loop studies were conducted at 4 weeks. Heart sections were analyzed for fibrosis and apoptosis, and relevant biochemical signaling cascades were assessed. Results After 4 weeks, diastolic function (EDPVR, EDP, tau, E/A ratio), systolic function (PRSW, ESPVR, dP/dtmax), and structural remodeling (LV chamber diameter, wall thickness) were all adversely affected in isoproterenol-treated rats. All these detrimental effects were attenuated in rats treated with Iso+IGF-1. Isoproterenol-dependent effects on BP were attenuated by IGF-1 treatment. Adrenergic sensitivity was blunted in isoproterenol-treated rats but was preserved by IGF-1 treatment. Immunoblots indicate that cardioprotective p110α signaling and activated Akt are selectively upregulated in Iso+IGF-1 treated hearts. Expression of iNOS was significantly increased in both the Iso and Iso+IGF-1 groups, however tetrahydrobiopterin (BH4) levels were decreased in the Iso group and maintained by IGF-1 treatment. Conclusion IGF-1 treatment attenuates diastolic and systolic dysfunction associated with chronic catecholamine-induced cardiomyopathy while preserving adrenergic sensitivity and promoting BH4 production. These data support the potential use of IGF-1 therapy for clinical applications for cardiomyopathies. PMID:26399932

  5. Echocardiographic assessment of systolic pulmonary arterial pressure in HIV-positive patients.

    Directory of Open Access Journals (Sweden)

    Mehrnaz Rasoulinejad

    2014-11-01

    Full Text Available Pulmonary hypertension is rare but is one of the complications that occur due to HIV infection. Symptoms of HIV-associated pulmonary arterial hypertension are often non-specific but the main symptom of the disease is dyspnea. In this cross-sectional study, we measured systolic pulmonary arterial pressure (SPAP by echocardiographic methods among HIV-positive patients who received ART. This research is a descriptive, cross-sectional study of 170 HIV-positive patients that was conducted in Imam-Khomeini hospital, Tehran, Iran during 2011-2013. All patients regularly received antiretroviral therapy at least for recent 2 years. There were not any cardiopulmonary symptoms (cough, dyspnea, exertional fatigue and chest discomfort in these patients. All participants underwent echocardiography to estimate SPAP. The participants comprised 108 males (63.5% and 62 females (46.5%. The mean age of patients was 41 years old, and the mean duration of HIV infection was 5.5 years. The mean CD4 cell count was 401 cell/µl. The principal regimen of antiretroviral therapy included two nucleoside reverse transcriptase inhibitor (NRTI and one non-nucleoside reverse transcriptase inhibitor (NNRTI in the hospital. The mean of systolic pulmonary arterial pressure was 25 mmHg in the participants; 156 (93.4% of them had SPAP ≤ 30 mmHg (normal, six (3.6% had SPAP: 31-35 mmHg (borderline and five (3% had SPAP > 35 mmHg (pulmonary hypertension. Our results indicated a significant increase of pulmonary hypertension in asymptomatic HIV-positive patients that had no association with any other risk factor. Also, antiretroviral therapy was not a risk factor for pulmonary hypertension in this study.

  6. Desmin loss and mitochondrial damage precede left ventricular systolic failure in volume overload heart failure.

    Science.gov (United States)

    Guichard, Jason L; Rogowski, Michael; Agnetti, Giulio; Fu, Lianwu; Powell, Pamela; Wei, Chih-Chang; Collawn, James; Dell'Italia, Louis J

    2017-07-01

    Heart failure due to chronic volume overload (VO) in rats and humans is characterized by disorganization of the cardiomyocyte desmin/mitochondrial network. Here, we tested the hypothesis that desmin breakdown is an early and continuous process throughout VO. Male Sprague-Dawley rats had aortocaval fistula (ACF) or sham surgery and were examined 24 h and 4 and 12 wk later. Desmin/mitochondrial ultrastructure was examined by transmission electron microscopy (TEM) and immunohistochemistry (IHC). Protein and kinome analysis were performed in isolated cardiomyocytes, and desmin cleavage was assessed by mass spectrometry in left ventricular (LV) tissue. Echocardiography demonstrated a 40% decrease in the LV mass-to-volume ratio with spherical remodeling at 4 wk with ACF and LV systolic dysfunction at 12 wk. Starting at 24 h and continuing to 4 and 12 wk, with ACF there is TEM evidence of extensive mitochondrial clustering, IHC evidence of disorganization associated with desmin breakdown, and desmin protein cleavage verified by Western blot analysis and mass spectrometry. IHC results revealed that ACF cardiomyocytes at 4 and 12 wk had perinuclear translocation of αB-crystallin from the Z disk with increased α, β-unsaturated aldehyde 4-hydroxynonelal. Use of protein markers with verification by TUNEL staining and kinome analysis revealed an absence of cardiomyocyte apoptosis at 4 and 12 wk of ACF. Significant increases in protein indicators of mitophagy were countered by a sixfold increase in p62/sequestosome-1, which is indicative of an inability to complete autophagy. An early and continuous disruption of the desmin/mitochondrial architecture, accompanied by oxidative stress and inhibition of apoptosis and mitophagy, suggests its causal role in LV dilatation and systolic dysfunction in VO. NEW & NOTEWORTHY This study provides new evidence of early onset (24 h) and continuous (4-12 wk) desmin misarrangement and disruption of the normal sarcomeric and mitochondrial

  7. Laboratory Measures of Postural Control During the Star Excursion Balance Test After Acute First-Time Lateral Ankle Sprain

    Science.gov (United States)

    Doherty, Cailbhe; Bleakley, Chris M.; Hertel, Jay; Caulfield, Brian; Ryan, John; Delahunt, Eamonn

    2015-01-01

    Context No researchers, to our knowledge, have investigated the immediate postinjury-movement strategies associated with acute first-time lateral ankle sprain (LAS) as quantified by center of pressure (COP) and kinematic analyses during performance of the Star Excursion Balance Test (SEBT). Objective To analyze the kinematic and COP patterns of a group with acute first-time LAS and a noninjured control group during performance of the SEBT. Design Case-control study. Setting University biomechanics laboratory. Patients or Other Participants A total of 81 participants with acute first-time LAS (53 men, 28 women; age = 23.22 ± 4.93 years, height = 1.73 ± 0.09 m, mass = 75.72 ± 13.86 kg) and 19 noninjured controls (15 men, 4 women; age = 22.53 ± 1.68 years, height = 1.74 ± 0.08 m, mass = 71.55 ± 11.31 kg). Intervention Participants performed the anterior (ANT), posterolateral (PL), and posteromedial (PM) reach directions of the SEBT. Main Outcome Measure(s) We assessed 3-dimensional kinematics of the lower extremity joints and associated fractal dimension (FD) of the COP path during performance of the SEBT. Results The LAS group had decreased normalized reach distances in the ANT, PL, and PM directions when compared with the control group on their injured (ANT: 58.16% ± 6.86% versus 64.86% ± 5.99%; PL: 85.64% ± 10.62% versus 101.14% ± 8.39%; PM: 94.89% ± 9.26% versus 107.29 ± 6.02%) and noninjured (ANT: 60.98% ± 6.74% versus 64.76% ± 5.02%; PL: 88.95% ± 11.45% versus 102.36% ± 8.53%; PM: 97.13% ± 8.76% versus 106.62% ± 5.78%) limbs (P postural control, as evidenced by the bilateral reduction in angular displacement of the lower extremity joints and reduced reach distances and FD of the COP path on the injured limb during performance of the SEBT. PMID:25811845

  8. Performance on the modified star excursion balance test at the time of return to sport following anterior cruciate ligament reconstruction.

    Science.gov (United States)

    Clagg, Sarah; Paterno, Mark V; Hewett, Timothy E; Schmitt, Laura C

    2015-06-01

    Cross-sectional. Objectives To compare performance on the modified Star Excursion Balance Test (SEBT) between participants with anterior cruciate ligament reconstruction (ACLR) at the time of return to sport and uninjured control participants. The modified SEBT is a clinical tool to assess neuromuscular control deficits. Deficits in dynamic stability and neuromuscular control persist after ACLR, but assessment with the modified SEBT in this population at the time of return to sport has not been reported. Sixty-six participants (mean age, 17.6 years) at the time of return to sport following unilateral primary ACLR (ACLR group) and 47 uninjured participants (mean age, 17.0 years) serving as a control group participated. For the modified SEBT, the anterior, posteromedial, and posterolateral reach distances were recorded. Lower extremity muscle strength was quantified with isokinetic dynamometry. Independent-sample t tests were used to evaluate performance differences between the ACLR group and the control group and between the ACLR subgroups. In the ACLR group, bivariate correlations determined the association of modified SEBT performance with time since surgery and lower extremity muscle strength. The ACLR group had lower anterior reach distances on the involved and uninvolved limbs compared to the control group. There were no differences observed between groups in reach distances for the posteromedial and posterolateral directions or in limb symmetry indices for any of the reach directions. In the ACLR group, time from surgery and meniscal status at the time of ACLR did not influence modified SEBT performance, whereas participants with patellar bone-tendon-bone grafts had a lower posterolateral reach distance compared to those with hamstring grafts. In the ACLR group, involved-limb hip abduction strength positively correlated with all reach distances, and quadriceps strength positively correlated with posterolateral reach. At the time of return to sport

  9. Assessment of regional systolic and diastolic myocardial function using tissue Doppler and strain imaging in dogs with dilated cardiomyopathy.

    Science.gov (United States)

    Chetboul, Valérie; Gouni, Vassiliki; Sampedrano, Carolina Carlos; Tissier, Renaud; Serres, François; Pouchelon, Jean-Louis

    2007-01-01

    Tissue Doppler Imaging (TDI) or strain (St) imaging could provide sensitive indices for early detection and treatment follow-up of canine dilated cardiomyopathy (DCM). Analysis of TDI and St features in dogs with overt DCM is a prerequisite before using these new criteria in prospective screenings of predisposed families or in clinical trials. Radial and longitudinal right and left myocardial motion, assessed by TDI and St variables, is altered in dogs with DCM. Case records for 26 dogs; 14 with DCM and 12 healthy controls of comparable age and weight were reviewed. A retrospective analysis was conducted of conventional echocardiography, 2-dimensional color TDI, and St imaging data. The DCM group was characterized by decreases in radial and longitudinal systolic velocity gradients of the left ventricular free wall (LVFW), radial and longitudinal absolute values of peak systolic St of the LVFW, and longitudinal systolic right ventricular (RV) velocities (all P canine DCM.

  10. [Stroke. are there any difference between patients with or without patent foramen ovale in left atrial appendage systolic function?].

    Science.gov (United States)

    Contreras, Alejandro E; Perrote, Federico; Concari, Ignacio; Brenna, Eduardo J; Lucero, Cecilia

    2012-01-01

    The aim of this study was to evaluate the systolic function of the left atrial appendage (LAA) in a group with and without patent foramen ovale (PFO) who suffered ischemic cerebrovascular events. Between September 2010 and October 2011, 17 patients were referred for transesophageal echocardiography (TEE) after suffering a stroke. PFO was defined as the passage of at least one bubble through atrial septum with bubble test. We compared systolic velocity in the appendage between patients with and without PFO and a control group. Were 8 women and 9 men, mean age 54.1 ± 19.5 years and 8 patients were under 55 years of age. All patients had suffered a ischemic cerebrovascular events, 41.2% had stroke, 52.9% transient ischemic attack and amaurosis fugax 5.9%. In the assessment of TEE, 11.8% had atrial septal aneurysm and 35.3% PFO. Mean LAA systolic velocity was 66.3 ± 20.3 cm / sec. There was no difference in systolic velocity of the LAA between patients with and without PFO (67.5 ± 11.8 cm / sec vs 65.7 ± 24.3 cm / sec respectively, p = 0.87). The control group of 8 patients, 5 women and 3 men, mean age 39.5 ± 18 years, had a LAA systolic velocity of 77.6 ± 28.9 cm / sec, no significant differences with ischemic patients. There were no differences in systolic function of the LAA between patients with and without PFO with ischemic cerebrovascular event.

  11. Cholecalciferol treatment to reduce blood pressure in older patients with isolated systolic hypertension: the VitDISH randomized controlled trial.

    Science.gov (United States)

    Witham, Miles D; Price, Rosemary J G; Struthers, Allan D; Donnan, Peter T; Messow, Claudia-Martina; Ford, Ian; McMurdo, Marion E T

    2013-10-14

    Observational data link low 25-hydroxyvitamin D levels to both prevalent blood pressure and incident hypertension. No clinical trial has yet examined the effect of vitamin D supplementation in isolated systolic hypertension, the most common pattern of hypertension in older people. To test whether high-dose, intermittent cholecalciferol supplementation lowers blood pressure in older patients with isolated systolic hypertension. Parallel group, double-blind, placebo-controlled randomized trial. Primary care clinics and hospital clinics. Patients 70 years and older with isolated systolic hypertension (supine systolic blood pressure >140 mm Hg and supine diastolic blood pressure blood pressure, 24-hour blood pressure, arterial stiffness, endothelial function, cholesterol level, insulin resistance, and b-type natriuretic peptide level during 12 months. A total of 159 participants were randomized (mean age, 77 years). Mean baseline office systolic blood pressure was 163/78 mm Hg. Mean baseline 25-hydroxyvitamin D level was 18 ng/mL. 25-Hydroxyvitamin D levels increased in the treatment group compared with the placebo group (+8 ng/mL at 1 year, P blood pressure (−1 [−6 to 4]/−2 [−4 to 1] mm Hg at 3 months and 1 [−2 to 4]/0 [−2 to 2] mm Hg overall treatment effect). No significant treatment effect was evident for any of the secondary outcomes (24-hour blood pressure, arterial stiffness, endothelial function, cholesterol level, glucose level, and walking distance). There was no excess of adverse events in the treatment group, and the total number of falls was nonsignificantly lower in the group receiving vitamin D (36 vs 46, P = .24). Vitamin D supplementation did not improve blood pressure or markers of vascular health in older patients with isolated systolic hypertension. isrctn.org Identifier: ISRCTN92186858.

  12. Solar cycle variations of the energetic H/He intensity ratio at high heliolatitudes and in the ecliptic plane

    Directory of Open Access Journals (Sweden)

    D. Lario

    Full Text Available We study the variability of the heliospheric energetic proton-to-helium abundance ratios during different phases of the solar cycle. We use energetic particle, solar wind, and magnetic field data from the Ulysses, ACE and IMP-8 spacecraft to compare the H/He intensity ratio at high heliographic latitudes and in the ecliptic plane. During the first out-of-ecliptic excursion of Ulysses (1992–1996, the HI-SCALE instrument measured corotating energetic particle intensity enhancements characterized by low values (< 10 of the 0.5–1.0 MeV nucleon-1 H/He intensity ratio. During the second out-of-ecliptic excursion of Ulysses (1999–2002, the more frequent occurrence of solar energetic particle events resulted in almost continuously high (< 20 values of the H/He ratio, even at the highest heliolatitudes reached by Ulysses. Comparison with in-ecliptic measurements from an identical instrument on the ACE spacecraft showed similar H/He values at ACE and Ulysses, suggesting a remarkable uniformity of energetic particle intensities in the solar maximum heliosphere at high heliolatitudes and in the ecliptic plane. In-ecliptic observations of the H/He intensity ratio from the IMP-8 spacecraft show variations between solar maximum and solar minimum similar to those observed by Ulysses at high heliographic latitudes. We suggest that the variation of the H/He intensity ratio throughout the solar cycle is due to the different level of transient solar activity, as well as the different structure and duration that corotating solar wind structures have under solar maximum and solar minimum conditions. During solar minimum, the interactions between the two different types of solar wind streams (slow vs. fast are strong and long-lasting, allowing for a continuous and efficient acceleration of interstellar pickup He +. During solar maximum, transient events of solar origin (characterized by high values of the H/He ratio are able to globally

  13. Simulation Exploration through Immersive Parallel Planes: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Brunhart-Lupo, Nicholas; Bush, Brian W.; Gruchalla, Kenny; Smith, Steve

    2016-03-01

    We present a visualization-driven simulation system that tightly couples systems dynamics simulations with an immersive virtual environment to allow analysts to rapidly develop and test hypotheses in a high-dimensional parameter space. To accomplish this, we generalize the two-dimensional parallel-coordinates statistical graphic as an immersive 'parallel-planes' visualization for multivariate time series emitted by simulations running in parallel with the visualization. In contrast to traditional parallel coordinate's mapping the multivariate dimensions onto coordinate axes represented by a series of parallel lines, we map pairs of the multivariate dimensions onto a series of parallel rectangles. As in the case of parallel coordinates, each individual observation in the dataset is mapped to a polyline whose vertices coincide with its coordinate values. Regions of the rectangles can be 'brushed' to highlight and select observations of interest: a 'slider' control allows the user to filter the observations by their time coordinate. In an immersive virtual environment, users interact with the parallel planes using a joystick that can select regions on the planes, manipulate selection, and filter time. The brushing and selection actions are used to both explore existing data as well as to launch additional simulations corresponding to the visually selected portions of the input parameter space. As soon as the new simulations complete, their resulting observations are displayed in the virtual environment. This tight feedback loop between simulation and immersive analytics accelerates users' realization of insights about the simulation and its output.

  14. Wafer plane inspection with soft resist thresholding

    Science.gov (United States)

    Hess, Carl; Shi, Rui-fang; Wihl, Mark; Xiong, Yalin; Pang, Song

    2008-10-01

    Wafer Plane Inspection (WPI) is an inspection mode on the KLA-Tencor TeraScaTM platform that uses the high signalto- noise ratio images from the high numerical aperture microscope, and then models the entire lithographic process to enable defect detection on the wafer plane[1]. This technology meets the needs of some advanced mask manufacturers to identify the lithographically-significant defects while ignoring the other non-lithographically-significant defects. WPI accomplishes this goal by performing defect detection based on a modeled image of how the mask features would actually print in the photoresist. There are several advantages to this approach: (1) the high fidelity of the images provide a sensitivity advantage over competing approaches; (2) the ability to perform defect detection on the wafer plane allows one to only see those defects that have a printing impact on the wafer; (3) the use of modeling on the lithographic portion of the flow enables unprecedented flexibility to support arbitrary illumination profiles, process-window inspection in unit time, and combination modes to find both printing and non-printing defects. WPI is proving to be a valuable addition to the KLA-Tencor detection algorithm suite. The modeling portion of WPI uses a single resist threshold as the final step in the processing. This has been shown to be adequate on several advanced customer layers, but is not ideal for all layers. Actual resist chemistry has complicated processes including acid and base-diffusion and quench that are not consistently well-modeled with a single resist threshold. We have considered the use of an advanced resist model for WPI, but rejected it because the burdensome requirements for the calibration of the model were not practical for reticle inspection. This paper describes an alternative approach that allows for a "soft" resist threshold to be applied that provides a more robust solution for the most challenging processes. This approach is just

  15. Simulation Exploration through Immersive Parallel Planes

    Energy Technology Data Exchange (ETDEWEB)

    Brunhart-Lupo, Nicholas J [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Bush, Brian W [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Gruchalla, Kenny M [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Smith, Steve [Los Alamos Visualization Associates

    2017-05-25

    We present a visualization-driven simulation system that tightly couples systems dynamics simulations with an immersive virtual environment to allow analysts to rapidly develop and test hypotheses in a high-dimensional parameter space. To accomplish this, we generalize the two-dimensional parallel-coordinates statistical graphic as an immersive 'parallel-planes' visualization for multivariate time series emitted by simulations running in parallel with the visualization. In contrast to traditional parallel coordinate's mapping the multivariate dimensions onto coordinate axes represented by a series of parallel lines, we map pairs of the multivariate dimensions onto a series of parallel rectangles. As in the case of parallel coordinates, each individual observation in the dataset is mapped to a polyline whose vertices coincide with its coordinate values. Regions of the rectangles can be 'brushed' to highlight and select observations of interest: a 'slider' control allows the user to filter the observations by their time coordinate. In an immersive virtual environment, users interact with the parallel planes using a joystick that can select regions on the planes, manipulate selection, and filter time. The brushing and selection actions are used to both explore existing data as well as to launch additional simulations corresponding to the visually selected portions of the input parameter space. As soon as the new simulations complete, their resulting observations are displayed in the virtual environment. This tight feedback loop between simulation and immersive analytics accelerates users' realization of insights about the simulation and its output.

  16. ARC Code TI: X-Plane Communications Toolbox (XPC)

    Data.gov (United States)

    National Aeronautics and Space Administration — The X-Plane Communications Toolbox (XPC) is an open source research tool used to interact with the commercial flight simulator software X-Plane. XPC allows users to...

  17. Dose distributions of pendulum fields in the field border plane

    International Nuclear Information System (INIS)

    Schrader, R.

    1986-01-01

    Calculations (program SIDOS-U2) and LiF measurements taken in a cylindric water phantom are used to investigate the isodose distributions of different pendulum irradiation methods (Co-60) in a plane which is parallel to the central ray plane and crosses the field borders at the depth of the axis. The dose values compared to the maximum values of the central ray plane are completely different for each pendulum method. In case of monoaxial pendulum methods around small angles, the maximum dose value found in the border plane is less than 50% of the dose in the central ray plane. The relative maximum of the border plane moves to tissues laying in a greater depth. In case of bi-axial methods, the maximum value of the border plane can be much more than 50% of the maximum dose measured in the central ray plane. (orig.) [de

  18. Vacuum Predisperser For A Large Plane-Grating Spectrograph

    Science.gov (United States)

    Engleman, R.; Palmer, B. A.; Steinhaus, D. W.

    1980-11-01

    A plane grating predisperser has been constructed which acts as an "order-sorter" for a large plane-grating spectrograph. This combination can photograph relatively wide regions of spectra in a single exposure with no loss of resolution.

  19. Plane wave fast color flow mode imaging

    DEFF Research Database (Denmark)

    Bolic, Ibrahim; Udesen, Jesper; Gran, Fredrik

    2006-01-01

    A new Plane wave fast color flow imaging method (PWM) has been investigated, and performance evaluation of the PWM based on experimental measurements has been made. The results show that it is possible to obtain a CFM image using only 8 echo-pulse emissions for beam to flow angles between 45...... degrees and 75 degrees. Compared to the conventional ultrasound imaging the frame rate is similar to 30 - 60 times higher. The bias, B-est of the velocity profile estimate, based on 8 pulse-echo emissions, is between 3.3% and 6.1% for beam to flow angles between 45 degrees and 75 degrees, and the standard...

  20. Synchrotron-radiation plane-wave topography

    International Nuclear Information System (INIS)

    Riglet, P.; Sauvage, M.; Petroff, J.F.; Epelboin, Y.

    1980-01-01

    A computer program based on the Takagi-Taupin differential equations for X-ray propagation in distorted crystals has been developed in order to simulate dislocation images in the Bragg case. The program is valid both for thin and thick crystals. Simulated images of misfit dislocations formed either in a thin epilayer or in a thick substrate are compared with experimental images obtained by synchrotron-radiation plane-wave topography. The influence of the various strain components on the image features is discussed. (author)

  1. PSB Chromaticity Correction in both Planes

    CERN Document Server

    Bartosik, Hannes; CERN. Geneva. ATS Department

    2017-01-01

    In view of the LHC injector upgrade program (LIU[1]), all LHC pre-accelerators and in particular the CERN Booster (PSB) are being reviewed for potential lattice optics and equipment optimizations. The option to correct the chromaticity in both planes would be very helpful for a better control of the beam in the presence of both non-linearities and space charge. Moreover, one could reduce decoherence phenomena that otherwise limit the usefulness of resonance measurement techniques based on a turn-by-turn BPM system.

  2. New plastic plane stress model for concrete

    International Nuclear Information System (INIS)

    Winnicki, A.; Cichon, Cz.

    1993-01-01

    In the paper a description of concrete behaviour in the plane stress case is given on the basis of the modified bounding surface plasticity theory. Three independent plastic mechanisms have been introduced describing axiatoric and deviatoric plastic strains and their coupling. All the new analytical formulae for material functions being in agreement with experiments and loading/unloading criteria have been proposed. In addition, for the proper description of concrete behaviour in tension a new, separate function of bounding surface shrinkage has been introduced. (author)

  3. The Simbol-X Focal Plane

    Science.gov (United States)

    Laurent, P.

    2009-05-01

    The Simbol-X focal plane is designed to detect photons focused by the mirror in the 0.5 to 100 keV energy band. Composed of two detectors, it will measure the position, energy, and arrival time of each incoming X-ray. On top of it will be a collimator to shield all photons not coming from the mirror field of view. The whole system is surrounded by an active and passive shielding in order to ensure the required very low background.

  4. Characterization of DECam focal plane detectors

    Energy Technology Data Exchange (ETDEWEB)

    Diehl, H.Thomas; Angstadt, Robert; Campa, Julia; Cease, Herman; Derylo, Greg; Emes, John H.; Estrada, Juan; Kibik, Donna; Flaugher, Brenna L.; Holland, Steve E.; Jonas, Michelle; /Fermilab /Madrid, CIEMAT /LBL, Berkeley /Argonne /Pennsylvania U.

    2008-06-01

    DECam is a 520 Mpix, 3 square-deg FOV imager being built for the Blanco 4m Telescope at CTIO. This facility instrument will be used for the 'Dark Energy Survey' of the southern galactic cap. DECam has chosen 250 ?m thick CCDs, developed at LBNL, with good QE in the near IR for the focal plane. In this work we present the characterization of these detectors done by the DES team, and compare it to the DECam technical requirements. The results demonstrate that the detectors satisfy the needs for instrument.

  5. The memory effect for plane gravitational waves

    Science.gov (United States)

    Zhang, P.-M.; Duval, C.; Gibbons, G. W.; Horvathy, P. A.

    2017-09-01

    We give an account of the gravitational memory effect in the presence of the exact plane wave solution of Einstein's vacuum equations. This allows an elementary but exact description of the soft gravitons and how their presence may be detected by observing the motion of freely falling particles. The theorem of Bondi and Pirani on caustics (for which we present a new proof) implies that the asymptotic relative velocity is constant but not zero, in contradiction with the permanent displacement claimed by Zel'dovich and Polnarev. A non-vanishing asymptotic relative velocity might be used to detect gravitational waves through the "velocity memory effect", considered by Braginsky, Thorne, Grishchuk, and Polnarev.

  6. On Helmholtz Problem for Plane Periodical Structures

    International Nuclear Information System (INIS)

    Akishin, P.G.; Vinitskij, S.I.

    1994-01-01

    The plane Helmholtz problem of the periodical disc structures with the phase shifts conditions of the solutions along the basis lattice vectors and the Dirichlet conditions on the basic boundaries is considered. The Green function satisfying the quasi periodical conditions on the lattice is constructed. The Helmholtz problem is reduced to the boundary integral equations for the simple layer potentials of this Green function. The methods of the discretization of the arising integral equations are proposed. The procedures of calculation of the matrix elements are discussed. The reality of the spectral parameter of the nonlinear continuous and discretized problems is shown. 8 refs., 2 figs

  7. Glycemic excursions are positively associated with HbA1c reduction from baseline after treatment with acarbose in patients with type 2 diabetes on metformin monotherapy.

    Science.gov (United States)

    Wang, Jun-Sing; Lee, I-Te; Lee, Wen-Jane; Lin, Shi-Dou; Su, Shih-Li; Tu, Shih-Te; Tseng, Yao-Hsien; Lin, Shih-Yi; Sheu, Wayne Huey-Herng

    2017-03-01

    The aim of the present study was to examine the association between glycemic excursions before treatment and HbA1c reduction after treatment intensification with acarbose or glibenclamide in patients with type 2 diabetes (T2D). Patients receiving single or dual oral antidiabetic drug treatment with an HbA1c of 7.0-11.0 % (53-97 mmol/mol) were switched to metformin monotherapy (500 mg, t.i.d.) for 8 weeks, followed by randomization to either acarbose (100 mg, t.i.d.) or glibenclamide (5 mg, t.i.d.) as add-on treatment for 16 weeks. Glycemic excursions were assessed as mean amplitude of glycemic excursions (MAGE) with 72-h ambulatory continuous glucose monitoring. Treatment efficacy was evaluated as relative HbA1c reduction (%), calculated as (baseline HbA1c - post-treatment HbA1c)/baseline HbA1c × 100. Fifty patients (mean [±SD] age 53.5 ± 8.2 years, 48 % men, mean baseline HbA1c 8.4 ± 1.2 %) were analyzed. Baseline MAGE was positively correlated with relative HbA1c reduction from baseline in patients treated with acarbose (r = 0.421, P = 0.029) but not glibenclamide (r = 0.052, P = 0.813). Linear regression analysis revealed that the association between baseline MAGE and relative HbA1c reduction from baseline (β = 0.125, P = 0.029) in patients treated with acarbose remained significant after adjustment for several confounders (P HbA1c reduction from baseline after treatment with acarbose, but not glibenclamide. These findings highlight the importance of glycemic excursions in individualized treatment for patients with T2D. © 2016 Ruijin Hospital, Shanghai JiaoTong University School of Medicine (SJTU), Chinese Society of Endocrinology and Chinese Endocrinologist Association and John Wiley & Sons Australia, Ltd.

  8. Effect of flow leakage on the benchmarking of FLOWTRAN with Mark-22 mockup flow excursion test data from Babcock and Wilcox

    International Nuclear Information System (INIS)

    Chen, Kuo-Fu.

    1992-10-01

    This report presents a revised analysis of the Babcock and Wilcox (B and W) downflow flow excursion tests that accounts for leakage between flow channels in the test assembly. Leak rates were estimated by comparing results from the downflow tests with those for upflow tests conducted using an identical assembly with some minor modifications. The upflow test assembly did not contain leaks. This revised analyses shows that FLOWTRAN with the SRS working criterion conservatively predicts onset of flow instability without using a local peaking factor to model heat transfer variations near the ribs

  9. In-plane and out-of-plane nonlinear dynamics of an axially moving beam

    International Nuclear Information System (INIS)

    Farokhi, Hamed; Ghayesh, Mergen H.; Amabili, Marco

    2013-01-01

    In the present study, the nonlinear forced dynamics of an axially moving beam is investigated numerically taking into account the in-plane and out-of-plane motions. The nonlinear partial differential equations governing the motion of the system are derived via Hamilton’s principle. The Galerkin scheme is then introduced to these partial differential equations yielding a set of second-order nonlinear ordinary differential equations with coupled terms. This set is transformed into a new set of first-order nonlinear ordinary differential equations by means of a change of variables. A direct time integration technique is conducted upon the new set of equations resulting in the bifurcation diagrams of Poincaré maps of the system. The dynamical characteristics of the system are investigated for different system parameters and presented through use of time histories, phase-plane portraits, Poincaré sections, and fast Fourier transforms

  10. 16-dimensional smooth projective planes with large collineation groups

    OpenAIRE

    Bödi, Richard

    1998-01-01

    Erworben im Rahmen der Schweizer Nationallizenzen (http://www.nationallizenzen.ch) Smooth projective planes are projective planes defined on smooth manifolds (i.e. the set of points and the set of lines are smooth manifolds) such that the geometric operations of join and intersection are smooth. A systematic study of such planes and of their collineation groups can be found in previous works of the author. We prove in this paper that a 16-dimensional smooth projective plane which admits a ...

  11. Predictors of high central blood pressure in young with isolated systolic hypertension

    Directory of Open Access Journals (Sweden)

    Radchenko GD

    2016-08-01

    Full Text Available G D Radchenko, O O Torbas, Yu M Sirenko State Institute National Scientific Center, M.D. Strazhesko Institute of Cardiology, National Academy of Medical Science, Kyiv, Ukraine Objective: According to the European Society of Cardiology/European Society of Hypertension 2013 guidelines, evaluation of aortic blood pressure (BP is needed in young with isolated systolic hypertension (ISH, but using special devices is not common, especially in Ukraine, where only a few centers have these devices. The purpose of our study was to identify the simple clinical predictors for differentiation (with or without elevated aortic systolic BP [SBP] of the young with ISH without the need for further extensive work-up. Patients and methods: The study included 44 young men (mean age: 32.2±1.3 years with office SBP ≥140 mmHg and office diastolic BP (DBP <90 mmHg (average: 153.4±2.1 mmHg and 83.4±1.7 mmHg, respectively. The following procedures were performed in all the subjects: body weight and height evaluation; measurement of office SBP, DBP, and heart rate; ambulatory BP monitoring; measurement of pulse wave velocity in arteries of elastic and muscle types and central SBP (cSBP; biochemical blood tests; electrocardiography; echocardiography; and carotid ultrasound investigations. Step-by-step multifactor regression analyses were used for finding the predictors of high cSBP. Results: Depending on the cSBP level, all the patients were divided into two groups: first group (n=17, subjects with normal cSBP, and second group (n=27, subjects with elevated cSBP. Patients in the second group were significantly older, with less height and higher body mass index; they had significantly higher levels of office SBP and DBP. Characteristics of target organ damage were within normal limits in both groups and did not differ significantly. Only pulse wave velocity in arteries of elastic type was significantly higher in the second group. The independent predictors of

  12. Effect of tender coconut water on systolic and diastolic blood pressure in prehypertensive women

    Directory of Open Access Journals (Sweden)

    Farapti Farapti

    2014-02-01

    . Dietary intakes of high potassium will decrease blood pressure (BP. Tender coconut water (TCW is a typical drink high in potassium. This study aimed to investigate the effect of TCW on BP in female teachers and employees prehypertension. Methods: The research was a parallel single blind randomized clinical trial. A total of 32 female prehypertension subjects aged 25-44 years. The subjects were selected using certain criteria and randomly allocated to one of two groups using block randomized, 16 subjects each. The treatment group received TCW 300 ml twice daily for 14 days and nutritional counseling, and the control group received water 300 ml twice daily for 14 days and nutritional counseling. Assessment of BP was done on day 0, day 8, and day 15. Statistical analysis were done using t-test and Mann-Whitney test. Results: Mean dietary intakes of potassium were 1420.28±405.54 mg/day or 30.22±8.63% compared to Recommended Dietary Allowance (RDA. During treatment period, potassium intake increased significantly in the treatment group. There were decreased BP in both groups, which were greater in the treatment group, but not statistically significant different (P > 0.05. The mean decrease of systolic BP was significant in treatment group (P = 0.031, meanwhile the mean decrease of diastolic BP was not significant (P=0.134. Conclusion: Tender coconut water 300 ml twice daily for 14 consecutive days has tendency to decrease systolic BP, but not diastolic blood pressure. (Health Science Indones 2013;2: 64-8Key words: coconut water, systolic and diastolic blood pressure

  13. On Finite Hjelmslev Planes of Parameters (pk−1, p)

    OpenAIRE

    Atilla Akpinar

    2010-01-01

    In this paper, we study on finite projective Hjelmslev planes M(Zq) coordinatized by Hjelmslev ring Zq (where prime power q = pk). We obtain finite hyperbolic Klingenberg planes from these planes under certain conditions. Also, we give a combinatorical result on M(Zq), related by deleting a line from lines in same neighbour.

  14. Multispectral linear array (MLA) focal plane mechanical and thermal design

    Science.gov (United States)

    Mitchell, A. S.; Kaminski, E. F.

    1982-01-01

    The mechanical and thermal design of an integrated focal plane subsystem of a Multispectral Linear Array (MLA) instrument is discussed in terms of focal-plane alignment, thermoelastic performance, and thermal requirements. The modular construction and thermal control of the focal plane array are discussed.

  15. The Curious Out-of-Plane Conductivity of PEDOT : PSS

    NARCIS (Netherlands)

    van de Ruit, Kevin; Katsouras, Ilias; Bollen, Dirk; van Mol, Ton; Janssen, Rene A. J.; de Leeuw, Dago M.; Kemerink, Martijn

    2013-01-01

    For its application as transparent conductor in light-emitting diodes and photovoltaic cells, both the in-plane and out-of-plane conductivity of PEDOT:PSS are important. However, studies into the conductivity of PEDOT:PSS rarely address the out-of-plane conductivity and those that do, report widely

  16. Fermi system with planes and charge reservoir: Anisotropic in-plane resistivity

    International Nuclear Information System (INIS)

    Levin, G.A.; Quader, K.F.

    1992-01-01

    The authors explore the normal state in-plane resistivity of a model Fermi system with two planes and a charge reservoir. When the Fermi energy lies near the top of one of the resulting sub-bands, the system can be described by two types of quasiparticle excitations with different energy spectra and relaxation times. They show that for certain stoichiometry, ρ ab is linear in temperature with positive or negative intercepts. A relation between the slopes and intercepts of resistivities in the a and b directions in untwinned crystals is derived. The results are in good agreement with experimental data on YBCO. 7 refs., 1 tab

  17. Clinical and Echocardiographic Evaluation of Regional Systolic Function Detected by Tissue Doppler Imaging in Hypertrophic Cardiomyopathy

    Directory of Open Access Journals (Sweden)

    A Sadeghpour

    2009-09-01

    Full Text Available Background: Hypertrophic cardiomyopathy (HCM is the most common type of the genetic cardiovasculardiseases. Regarding to tremendous heterogeneity in the phenotypic expression of HCM, which is generally unrelatedto genotype, we aimed to study, clinical and echocardiographic parameters such as Tissue Doppler Imaging(TDI in various subtypes of HCM patients and evaluate the influence of race and gender in Iranian patients.Methods: Patients with HCM underwent a complete clinical and echocardiographic study including TDI toassess regional systolic contraction( in the 12 segments and early diastolic annular velocity (Em from theseptal mitral annulus.Results: The study comprised 41 patients (20 women, mean age = 41 ± 15 years with mean LVEF 55%±4.8%and mean maximal septal thickness 2.07cm. Considering LVOT gradient>30mmHg, hypertrophic obstructivecardiomyopathy (HOCM was found in 18 (45%. Asymmetric septal hypertrophy (ASH existed in 27 patients(67%, systolic anterior motion of anterior mitral leaflet (SAM in 25 persons (64%. Nineteen patients (46.3%were included in NYHA function class (FC II and 6 (14.7% in FC III or higher. We found syncope in 10(24.4%, chest pain in 4 (9.8%, atrial fibrilation in 14.6 % and ventricular arrhythmias in (17.1% of patients.History of ICD was seen in 7 (17.1% and PPM in 9 cases. Mean E’ velocity was 5.44± 1.65 cm/sec and S velocity5.70± 1.49 cm/sec with significant lower S velocity and E’ in syncope patients. Overall, HOCM patients hadgrade II diastolic dysfunction with E/É >15(17.54±7.46. Majority (25 of cases (61% were categorized in typeIII of HCM. RV involvement was observed in 11 patients (28.2%.No significant differences existed betweenprevalence of syncope and dysrhythmia among HCM and HOCM patients.Conclusion: In our study, we found lower detection of latent HOCM, compared to other studies, suggestive ofinadequate use of appropriate provocative maneuvers such as exercise stress echocardiography and amyl

  18. Traces of chiral symmetry on light planes

    International Nuclear Information System (INIS)

    Sazdjian, Hagop.

    1975-01-01

    The possibility of a description of the hadronic world by field theories defined on light planes and formulated in terms of three interacting quark field variables has been investigated. The framework of models where the chiral symmetry breaking is produced by the only mechanical masses of quarks has been considered. The hypothesis that the light plane charges generate in the real world approximate symmetries of one particle states has also been emitted. The projection of the algebraic structure of the observables in the space of physical states have yielded various relations in terms of the masses and couplings of the low lying mesons. They seem to be in agreement with experimental data, and suggest the consistency of the adopted model to describe symmetry breaking phenomena. The quark mechanical masses m(u) approximately 30MeV and m(s) approximately 200MeV have also been estimated. The smallness of these masses in respect to those of hadrons seems to indicate that they do not constitute the only mass scale of the hadronic world, but that there should exist another scale parameter, independent of the quark mechanical masses, and symmetric of SU(3) [fr

  19. The plane motion control of the quadrocopter

    Directory of Open Access Journals (Sweden)

    A. N. Kanatnikov

    2015-01-01

    Full Text Available Among a large number of modern flying vehicles, the quadrocopter relates to unmanned aerial vehicles (UAV which are relatively cheap and easy to design. Quadrocopters are able to fly in bad weather, hang in the air for quite a long time, observe the objects and perform many other tasks. They have been applied in rescue operations, in agriculture, in the military and many other fields.For quadrocopters, the problems of path planning and control are relevant. These problems have many variants in which limited resources of modern UAV, possible obstacles, for instance, for flying in a cross-country terrain or in a city environment and weather conditions (particularly, wind conditions are taken into account. Many research studies are concerned with these problems and reflected in series of publications (note the interesting survey [1] and references therein. Various methods were used for the control synthesis for these vehicles: linear approximations [2], sliding mode control [3], the covering method [4] and so on.In the paper, a quadrocopter is considered as a rigid body. The kinematic and dynamic equations of the motion are analyzed. Two cases of motion are emphasized: a motion in a vertical plane and in a horizontal plane. The control is based on transferring of the affine system to the canonical form [5] and the nonlinear stabilization method [6].

  20. The Sentinel-4 UVN focal plane assemblies

    Science.gov (United States)

    Hinger, Jürgen; Hohn, Rüdiger; Gebhardt, Eyk; Reichardt, Jörg

    2017-09-01

    The Sentinel-4 UVN Instrument is a dispersive imaging spectrometer covering the UV-VIS and the NIR wavelength. It is developed and built under an ESA contract by an industrial consortium led by Airbus Defence and Space. It will be accommodated on board of the MTG-S (Meteosat Third Generation - Sounder) satellite that will be placed in a geostationary orbit over Europe sampling data for generating two-dimensional maps of a number of atmospheric trace gases. The incoming light is dispersed by reflective gratings and detected by the two (UVVIS and NIR) CCDs mounted inside the focal plane assemblies. Both CCD detectors acquire spectral channels and spatial sampling in two orthogonal directions and will be operated at about 215 K mainly to minimize random telegraph signal effects and to reduce dark current. Stringent detector temperature as well as alignment stability requirements of less than +/-0.1 K per day respectively of less than 2 micrometers/2 arcseconds from ground to orbit are driving the FPA thermo-mechanical design. A specific FPA design feature is the redundant LED-calibration system for bad pixel detection as well as pixel gain and linearity monitoring. This paper reports on the design and qualification of the Focal Plane Assemblies with emphasis on thermo-mechanical as well as alignment stability verification.