U.S.-China Relations: Policy Issues

Science.gov (United States)

2010-03-12

China Relations: Policy Issues Congressional Research Service 8 Center; the U.S.-China Energy Efficiency Action Plan; and the U.S.-China Energy...January 25, 2010. 28 Liu Shengjun, “How to Better Use Forex Reserves,” China Daily, January 13, 2010. 29 Paul R. La Monica, “China Still Likes Us…For...or commercialization of carbon capture and sequestration technology, improve energy efficiency , or renewable energy sources. H.R. 2454 Waxman

DETECTION OF WEAK CIRCUMSTELLAR GAS AROUND THE DAZ WHITE DWARF WD 1124-293: EVIDENCE FOR THE ACCRETION OF MULTIPLE ASTEROIDS

Energy Technology Data Exchange (ETDEWEB)

Debes, J. H. [Space Telescope Science Institute, 3700 San Martin Dr., Baltimore, MD 21218 (United States); Kilic, M. [Homer L. Dodge Department of Physics and Astronomy, The University of Oklahoma, 440 W. Brooks St., Norman, OK 73019 (United States); Faedi, F. [Astrophysics Research Centre, School of Mathematics and Physics, Queen' s University Belfast, University Road, Belfast, BT7 1NN (United Kingdom); Shkolnik, E. L. [Lowell Observatory, Flagstaff, AZ 86001 (United States); Lopez-Morales, M. [Institut de Ciencies de l' Espai (CSIC-IEEC), Campus UAB, Facultat de Ciencies, Torre C5, parell, 2a pl, E-08193 Bellaterra, Barcelona (Spain); Weinberger, A. J.; Slesnick, C. [Department of Terrestrial Magnetism, Carnegie Institution of Washington, 5249 Broad Branch RD, N.W., Washington, DC 20015 (United States); West, R. G. [Department of Physics and Astronomy, University of Leicester, University Road, Leicester, LE1 7RH (United Kingdom)

2012-07-20

Single metal-polluted white dwarfs with no dusty disks are believed to be actively accreting metals from a circumstellar disk of gas caused by the destruction of asteroids perturbed by planetary systems. We report, for the first time, the detection of circumstellar Ca II gas in absorption around the DAZ WD 1124-293, which lacks an infrared excess. We constrain the gas to >7 R{sub WD} and <32000 AU, and estimate it to be at {approx}54 R{sub WD}, well within WD 1124-293's tidal disruption radius. This detection is based on several epochs of spectroscopy around the Ca II H and K lines ({lambda} = 3968 A, 3933 A) with the MIKE spectrograph on the Magellan/Clay Telescope at Las Campanas Observatory. We confirm the circumstellar nature of the gas by observing nearby sightlines and finding no evidence for gas from the local interstellar medium. Through archival data we have measured the equivalent width of the two photospheric Ca lines over a period of 11 years. We see <5%-7% epoch-to-epoch variation in equivalent widths over this time period, and no evidence for long term trends. The presence of a circumstellar gas implies a near edge-on inclination to the system, thus we place limits to short period transiting planetary companions with R > R{sub Circled-Plus} using the Wide Angle Search for Planets survey. The presence of gas in orbit around WD 1124-293 implies that most DAZs could harbor planetary systems. Since 25%-30% of white dwarfs show metal line absorption, the dynamical process for perturbing small bodies must be robust.

High-heat tank safety issue resolution program plan. Revision 2

International Nuclear Information System (INIS)

Wang, O.S.

1994-12-01

The purpose of this program plan is to provide a guide for selecting corrective actions that will mitigate and/or remediate the high-heat waste tank safety issue for single-shell tank 241-C-106. The heat source of approximately 110,000 Btu/hr is the radioactive decay of the stored waste material (primarily 90 Sr) inadvertently transferred into the tank in the later 1960s. Currently, forced ventilation, with added water to promote thermal conductivity and evaporation cooling, is used for heat removal. The method is very effective and economical. At this time, the only viable solution identified to permanently resolve this safety issue is the removal of heat-generating waste in the tank. This solution is being aggressively pursued as the only remediation method to this safety issue, and tank 241-C-106 has been selected as the first single-shell tank for retrieval. The current cooling method and other alternatives are addressed in this program as means to mitigate this safety issue before retrieval. This program plan has three parts. The first part establishes program objectives and defines safety issue, drivers, and resolution criteria and strategy. The second part evaluates the high-heat safety issue and its mitigation and remediation methods and other alternatives according to resolution logic. The third part identifies major tasks and alternatives for mitigation and resolution of the safety issue. A table of best-estimate schedules for the key tasks is also included in this program plan

High-heat tank safety issue resolution program plan

International Nuclear Information System (INIS)

Wang, O.S.

1993-12-01

The purpose of this program plan is to provide a guide for selecting corrective actions that will mitigate and/or remediate the high-heat waste tank safety issue for single-shell tank (SST) 241-C-106. This program plan also outlines the logic for selecting approaches and tasks to mitigate and resolve the high-heat safety issue. The identified safety issue for high-heat tank 241-C-106 involves the potential release of nuclear waste to the environment as the result of heat-induced structural damage to the tank's concrete, if forced cooling is interrupted for extended periods. Currently, forced ventilation with added water to promote thermal conductivity and evaporation cooling is used to cool the waste. At this time, the only viable solution identified to resolve this safety issue is the removal of heat generating waste in the tank. This solution is being aggressively pursued as the permanent solution to this safety issue and also to support the present waste retrieval plan. Tank 241-C-106 has been selected as the first SST for retrieval. The program plan has three parts. The first part establishes program objectives and defines safety issues, drivers, and resolution criteria and strategy. The second part evaluates the high-heat safety issue and its mitigation and remediation methods and alternatives according to resolution logic. The third part identifies major tasks and alternatives for mitigation and resolution of the safety issue. Selected tasks and best-estimate schedules are also summarized in the program plan

Editorial: Special Issue on Financial Planning

Directory of Open Access Journals (Sweden)

Mark Brimble

2012-11-01

Full Text Available AbstractThe special edition presents current research in the area of financial planning. With the continual upheaval inglobal financial markets (including Australia, the general trend towards self-funded retirement and lessreliance on the state, financial crises and the continual regulatory changes in the financial markets, this issue istimely and topical. This is the third special edition on financial planning, providing an excellent outlet forquality research in financial planning.

Introduction - AABFJ Financial Planning Special Issue 2009

Directory of Open Access Journals (Sweden)

Ciorstan J. Smark

2009-03-01

Full Text Available This special issue draws on recent work of financial planning specialists, finance specialists and economists todocument some of the trends, perception and challenges of financial planning in 2009. This diversity ofcontributors reflects the diversity and the multiplicity of influences that impact on financial planning.

Approval plans issues and innovations

CERN Document Server

Katz, Linda S

2013-01-01

How can you, as an acquisition librarians, keep current on the output of hundreds of publishers? The answer, of course, is that you cannot. For over 30 years, approval plans have been used by librarians to acquire current titles, save staff time, and build core collections. Even today, these reasons seem appropriate, as libraries try to maintain up-to-date collections and control personnel and operating budgets. However, as shown in Approval Plans: Issues and Innovations, the use of approval plans is not so simple and straightforward; their use is subject to complex procedures and policies--an

THE NIGERIAN GAS MASTER-PLAN, INVESTMENT OPPORTUNITIES, CHALLENGES, ISSUES AFFECTING POWER SECTOR: AN ANALYSIS

Directory of Open Access Journals (Sweden)

R. INGWE

2014-11-01

Full Text Available The Nigerian Gas Master-Plan, Investment Opportunities, Challenges, Issues Affecting Power Sector: an Analysis. The objective of this article is to contribute towards understanding of the Nigerian Gas Master Plan (NGMP/Plan and its bifurcations with key socio-economic development factors. I applied the method of discourse to bring to being some points that have hitherto been unknown about the Master-plan and its inter-relationships and bifurcations. Elaborated here are the spectacular gains that have accrued to the Latin American country, Trinidad and Tobago, from its recent development of natural gas resources. This was considered suitable and significant here for highlighting that if such spectacular achievements could be realized from Trinidad and Tobago’s relatively smaller gas deposit (15.3 tcf, probable reserves (8.4 tcf, possible reserves (6.2 tcf would be by far greater considering Nigeria’s larger natural gas reserves (184 tcf wealth as earlier stated. I show that the Plan is well designed relevant to addressing Nigeria’s current development needs generally. It presents potentials for stimulating Nigeria’s economic growth by harnessing the country’s abundant natural gas reserves. The Plan enumerates/ elaborates huge investment opportunities. Some challenges likely to be faced in the implementation/management of the Plan are already being surmounted as recent reports show that some of its key investments have been realized and the required infrastructure are being provided. Regarding the issues in the Master-plan that are likely to affect and are affecting Nigeria’s power sector development, I reckon that they are mostly positive factors due to the way the plan promises to stimulate electricity generation in our country.

Issues for a Model of Language Planning.

Science.gov (United States)

Bamgbose, Ayo

1989-01-01

Examines the following issues as they relate to a model of language planning: (1) types of decisions (policy or implemental, higher- or lower-level, rational or arbitrary); (2) the planning mechanism; (3) the role of fact finding (prepolicy, preimplementation, and intraimplementation); (4) levels of planning; and (5) the nature of status versus…

Legal issues in cash balance pension plan conversions.

Science.gov (United States)

Forman, J B

2001-01-01

Replacing a traditional pension with a cash balance plan raises a number of complicated and unsettled legal issues, including the protection of accrued benefits, the rate of benefit accrual, age discrimination and notice requirements. This article discusses those issues and concludes that routine conversions to cash balance plans appear to be legal both currently and into the foreseeable future.

WdStuAp, an APSES transcription factor, is a regulator of yeast-hyphal transitions in Wangiella (Exophiala) dermatitidis.

Science.gov (United States)

Wang, Qin; Szaniszlo, Paul J

2007-09-01

APSES transcription factors are well-known regulators of fungal cellular development and differentiation. To study the function of an APSES protein in the fungus Wangiella dermatitidis, a conidiogenous and polymorphic agent of human phaeohyphomycosis with yeast predominance, the APSES transcription factor gene WdSTUA was cloned, sequenced, disrupted, and overexpressed. Analysis showed that its derived protein was most similar to the APSES proteins of other conidiogenous molds and had its APSES DNA-binding domain located in the amino-terminal half. Deletion of WdSTUA in W. dermatitidis induced convoluted instead of normal smooth colony surface growth on the rich yeast maintenance agar medium yeast extract-peptone-dextrose agar (YPDA) at 37 degrees C. Additionally, deletion of WdSTUA repressed aerial hyphal growth, conidiation, and invasive hyphal growth on the nitrogen-poor, hypha-inducing agar medium potato dextrose agar (PDA) at 25 degrees C. Ectopic overexpression of WdSTUA repressed the convoluted colony surface growth on YPDA at 37 degrees C, and also strongly repressed hyphal growth on PDA at 25 degrees C and 37 degrees C. These new results provide additional insights into the diverse roles played by APSES factors in fungi. They also suggest that the transcription factor encoded by WdSTUA is both a positive and negative morphotype regulator in W. dermatitidis and possibly other of the numerous human pathogenic, conidiogenous fungi capable of yeast growth.

The WD+He star binaries as the progenitors of type Ia supernovae

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Wang Bo

2017-12-01

Full Text Available Employing the MESA stellar evolution code, we computed He accretion onto carbon-oxygen white dwarfs (CO WDs.We found two possible outcomes for models in which the WD steadily grows in mass towards the Chandrasekhar limit. For relatively low He-accretion rates carbon ignition occurs in the center, leading to a type Ia supernova (SN Ia explosion, whereas for relatively high accretion rates carbon is ignited off-center, probably leading to collapse. Thus the parameter space producing SNe Ia is reduced compared to what was assumed in earlier papers, in which the possibility of off-center ignition was ignored. We then applied these results in binary population synthesis modelling, finding a modest reduction in the expected birthrate of SNe Ia resulting from the WD+He star channel.

U.S. Nuclear Regulatory Commission human factors program plan

International Nuclear Information System (INIS)

1986-04-01

The purpose of the U.S. Nuclear Regulatory Commission (NRC) Human Factors Program Plan is to ensure that proper consideration is given to human factors in the design and operation of nuclear facilities. This revised plan addresses human factors issues related to the operation of nuclear power plants (NPPs). The three issues of concern are (1) the activities planned to provide the technical bases to resolve the remaining tasks related to human factors as described in NUREG-0660, The NRC Action Plan Developed as a Result of the TMI-2 Accident, and NUREG-0737, Clarification of TMI Action Plan Requirements; (2) the need to address the additional human factors efforts that were identified during implementation of the Action Plan; and (3) the actual fulfillment of those developmental activities specified in Revision 1 of this plan. The plan represents a systematic approach for addressing high priority human factors concerns important to NPP safety in FY 1986 through 1987

Rancang Bangun Sistem Smart Charging menggunakan Panel Surya pada Robot 6WD berbasis Mikrokontroler Arduino

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made yogi hendrayanto

2018-03-01

Full Text Available Ilmu pengetahuan dan teknologi dalam bidang robotika pada saat ini berkembang dengan sangat cepat. Teknologi robotika pada dasarnya dikembangkan dengan tujuan untuk membantu manusia dalam melakukan pekerjaan tertentu, seperti pekerjaan yang berisiko tinggi, pekerjaan yang tidak bisa dikerjakan oleh tangan manusia secara langsung dan pekerjaan yang membutuhkan ketelitian tinggi. Pada saat ini, robot masih dikendalikan secara manual oleh manusia menggunakan Baterai sebagai sumber energi robot dan melakukan pengisian secara manual. Berdasarkan hal tersebut maka ada suatu keinginan untuk berkontribusi dalam pengembangan teknologi robot 6WD yaitu dengan merancang sebuah sistem Smart charging menggunakan Panel surya sebagai sumber energi untuk melakukan pengisian baterai robot secara langsung. Sistem yang dibuat, nantinya dapat membuat robot 6WD, bergerak dengan cara manual menggunakan inputan dari komputer yang dikontrol manual dari manusia. Manusia hanya perlu menggerakkan dan dapat melihat kondisi dari 2 buah baterai robot 6WD dari Komputer, kemudian komunikasi yang terjadi antara komputer dengan robot dapat dilakukan secara dua arah, agar robot dapat memberikan informasi balik kepada komputer, baik itu daya baterai, loss area dan lain sebagainya.Arduino Mega 2560 digunakan sebagai sistem utama yang mengolah semua data input dan output pada sistem. Modul HM-TRP befungsi untuk mengirimkan data dari robot ke komputer untuk ditampilkan.Pengiriman informasi robot 6WD meliputi informasi kondisi status 2 buah baterai, arus baterai, tegangan baterai, dan arah dari gerakan robot yang akan dikendalikan melalui GCS(Ground Control Station.   [TURNITIN CHECK 8%, 18042017

Overexpression of MIP2, a novel WD-repeat protein, promotes proliferation of H9c2 cells

International Nuclear Information System (INIS)

Wei, Xing; Song, Lan; Jiang, Lei; Wang, Guiliang; Luo, Xinjing; Zhang, Bin; Xiao, Xianzhong

2010-01-01

WD40 repeat proteins have a wide range of diverse biological functions including signal transduction, cell cycle regulation, RNA splicing, and transcription. Myocardial ischemic preconditioning up-regulated protein 2 (MIP2) is a novel member of the WD40 repeat proteins superfamily that contains five WD40 repeats. Little is known about its biological role, and the purpose of this study was to determine the role of MIP2 in regulating cellular proliferation. Transfection and constitutive expression of MIP2 in the rat cardiomyoblast cell line H9c2 results in enhanced growth of those cells as measured by cell number and is proportional to the amount of MIP2 expressed. Overexpression of MIP2 results in a shorter cell cycle, as measured by flow cytometry. Collectively, these data suggest that MIP2 may participate in the progression of cell proliferation in H9c2 cells.

The pleiotropic effect of WD-40 domain containing proteins on cellular differentiation and production of secondary metabolites in Streptomyces coelicolor

Czech Academy of Sciences Publication Activity Database

Ulrych, Aleš; Goldová, Jana; Petříček, Miroslav; Benada, Oldřich; Kofroňová, Olga; Rampírová, Petra; Petříčková, Kateřina; Branny, Pavel

2013-01-01

Roč. 9, č. 6 (2013), s. 1453-1469 ISSN 1742-206X R&D Projects: GA MŠk LH12191; GA MŠk LH12055; GA MŠk 2B08064 Institutional support: RVO:61388971 Keywords : AERIAL MYCELIUM FORMATION * WD-REPEAT PROTEINS * BIOSYNTHESIS GENE-CLUSTER Subject RIV: EE - Microbiology, Virology Impact factor: 3.183, year: 2013

Dgp71WD is required for the assembly of the acentrosomal Meiosis I spindle, and is not a general targeting factor for the γ-TuRC

Directory of Open Access Journals (Sweden)

Richard F. Reschen

2012-03-01

Dgp71WD/Nedd1 proteins are essential for mitotic spindle formation. In human cells, Nedd1 targets γ-tubulin to both centrosomes and spindles, but in other organisms the function of Dgp71WD/Nedd1 is less clear. In Drosophila cells, Dgp71WD plays a major part in targeting γ-tubulin to spindles, but not centrosomes, while in Xenopus egg extracts, Nedd1 acts as a more general microtubule (MT organiser that can function independently of γ-tubulin. The interpretation of these studies, however, is complicated by the fact that some residual Dgp71WD/Nedd1 is likely present in the cells/extracts analysed. Here we generate a Dgp71WD null mutant lacking all but the last 12 nucleotides of coding sequence. The complete loss of Dgp71WD has no quantifiable effect on γ-tubulin or Centrosomin recruitment to the centrosome in larval brain cells. The recruitment of γ-tubulin to spindle MTs, however, is severely impaired, and spindle MT density is reduced in a manner that is indistinguishable from cells lacking Augmin or γ-TuRC function. In contrast, the absence of Dgp71WD leads to defects in the assembly of the acentrosomal female Meiosis I spindle that are more severe than those seen in Augmin or γ-TuRC mutants, indicating that Dgp71WD has additional functions that are independent of these complexes in oocytes. Moreover, the localisation of bicoid RNA during oogenesis, which requires γ-TuRC function, is unperturbed in Dgp71WD120 mutants. Thus, Dgp71WD is not simply a general cofactor required for γ-TuRC and/or Augmin targeting, and it appears to have a crucial role independent of these complexes in the acentrosomal Meiosis I spindle.

Constraining convection parameters from the light curve shapes of pulsating white dwarf stars: the cases of EC 14012-1446 and WD 1524-0030

Energy Technology Data Exchange (ETDEWEB)

Handler, G; Lendl, M; Beck, P [Institut fuer Astronomie, Universitaet Wien, Tuerkenschanzstrasse 17, A-1180 Wien (Austria); Provencal, J L; Montgomery, M H [Mt. Cuba Observatory and Department of Physics and Astronomy, University of Delaware, 223 Sharp Laboratory, Newark, DE 19716 (Cuba); Romero-Colmenero, E [South AfricAN Astronomical Observatory, PO Box 9, Observatory 7935 (South Africa); Sanchawala, K; Chen, W-P [Graduate Institute of Astronomy, National Central University, Chung-Li 32054, Taiwan (China); Wood, M A; Silver, I [Department of Physics and Space Sciences and SARA Observatory, Florida Institute of Technology, Melbourne, FL 32901 (United States)], E-mail: handler@astro.univie.ac.at

2008-10-15

Montgomery [1] developed a method to probe convection in pulsating white dwarf stars which allows the recovery of the thermal response time of the convection zone by fitting observed nonsinusoidal light curves. He applied this method to two objects; the Whole Earth Telescope (WET) observed the pulsating DB white dwarf GD 358 for just this purpose. Given this WET run's success, it is time to extend Montgomery's method to pulsating DA white dwarf (ZZ Ceti) stars. We present observations of two ZZ Ceti stars, WD 1524-0030 and EC 14012-1446, both observed from multiple sites. EC 14012-1446 seems better suited thAN WD1524-0030 for a future WET run because it has more pulsation modes excited and because it pulsation spectrum appears to be more stable in time. We call for participation in this effort to take place in April 2008.

'Public theology' from within the church? A reflection on aspects of the theology of W.D. Jonker (1929-2006)

OpenAIRE

Naudé, Piet J.

2014-01-01

In this essay, aspects of the work of theologian W.D. (Willie) Jonker are reframed to complement current debates about �public theology� in South Africa. The introduction points out that Jonker worked during a crucial period in South Africa�s history and that his theology is intrinsically linked to the church struggle between 1955 and 1994. The second part reframes Jonker�s theology as a public theology from within the church by referring to his understanding of preaching, confessions and pub...

Rancang Bangun Robot 6WD Dengan Sensor Gas TGS2600 Menggunakan Metode Wall Following Berbasis Arduino Mega 2560

Directory of Open Access Journals (Sweden)

I Made Arya Budhana

2017-07-01

Full Text Available Intisari— Perkembangan teknologi khususnya dibidang robotika saat ini sangat pesat, Salah satu bentuk aplikasi dari teknologi robotika yang erat kaitannya dengan sistem kontrol adalah wheel mobile robot. Beberapa metode dapat dilakukan untuk mendistribusikan gas alam salah satunya dengan pipa. Distribusi gas alam dengan menggunakan pipa sering mengalami kendala kebocoran yang disebabkan usia dari pipa distribusi yang sudah cukup tua. Untuk mempermudah pemantauan pipa gas yang berada di bawah tanah digunakan robot 6 WD (wheel drive yang memiliki 6 roda dan penggerak pada setiap rodanya untuk mengatasi medan yang berat. Pergerakan dari robot 6 WD mengacu pada sensor ultrasonik SRF HC-SR04, metode ini dinamakan wall following. Sensor gas tipe TGS dari figaro dimanfaatkan untuk mengetahui adanya kebocoran gas  pada pipa atau tidak. Selain itu, robot ini juga dilengkapi dengan kamera untuk mengirim gambar kerusakan pipa pada user agar dapat segera dilakukan perbaikan. Arduino Mega 2560 digunakan sebagai otak pada robot 6 WD yang bertugas untuk mengolah data yang masuk dan memberikan instruksi pada robot 6WD. Pengiriman data dari robot 6 WD pada pengguna meliputi, data sensor gas, data sensor kompas, data sensor jarak dan gambar kerusakan pada pipa. Seluruh data dapat dilihat pada GCS (Ground Control Station.   [TRUNITIN CHECK 20%, 26042017

Tank 241-S-107 tank characterization plan. Revision 1

International Nuclear Information System (INIS)

Homi, C.S.

1995-01-01

This document is a plan that identifies the information needed to address relevant issues concerning short-term and long-term safe storage and long-term management of Single-Shell Tank (SST) 241-S-107

Status of safety issues at licensed power plants: TMI Action Plan requirements; unresolved safety issues; generic safety issues; other multiplant action issues

International Nuclear Information System (INIS)

1993-12-01

As part of ongoing US Nuclear Regulatory Commission (NRC) efforts to ensure the quality and accountability of safety issue information, the NRC established a program for publishing an annual report on the status of licensee implementation and NRC verification of safety issues in major NRC requirements areas. This information was initially compiled and reported in three NUREG-series volumes. Volume 1, published in March 1991, addressed the status of Three Mile Island (TMI) Action Plan Requirements. Volume 2, published in May 1991, addressed the status of unresolved safety issues (USIs). Volume 3, published in June 1991, addressed the implementation and verification status of generic safety issues (GSIs). The first annual supplement, which combined these volumes into a single report and presented updated information as of September 30, 1991, was published in December 1991. The second annual supplement, which provided updated information as of September 30, 1992, was published in December 1992. Supplement 2 also provided the status of licensee implementation and NRC verification of other multiplant action (MPA) issues not related to TMI Action Plan requirements, USIs, or GSIs. This third annual NUREG report, Supplement 3, presents updated information as of September 30, 1993. This report gives a comprehensive description of the implementation and verification status of TMI Action Plan requirements, safety issues designated as USIs, GSIs, and other MPAs that have been resolved and involve implementation of an action or actions by licensees. This report makes the information available to other interested parties, including the public. Additionally, this report serves as a follow-on to NUREG-0933, ''A Prioritization of Generic Safety Issues,'' which tracks safety issues until requirements are approved for imposition at licensed plants or until the NRC issues a request for action by licensees

Rolling Stock Planning at DSB S-tog - Processes, Cost Structures and Requirements

DEFF Research Database (Denmark)

Thorlacius, Per

A central issue for operators of suburban passenger train transport systems is providing sufficient number of seats for the passengers while at the same time minimising operating costs. The process of providing this is called rolling stock planning. This technical report documents the terminology......, the processes, the cost structures and the requirements for rolling stock planning at DSB S-tog, the suburban passenger train operator of the City of Copenhagen. The focus of the technical report is directed at practical train operator oriented issues. The technical report is thought to serve as a basis...... for investigating better methods to perform the rolling stock planning (to be the topic of later papers). This technical report is produced as a part of the current industrial Ph. D. project to improve the rolling stock planning process of DSB S-tog....

WD60/FAP163 is a dynein intermediate chain required for retrograde intraflagellar transport in cilia

Science.gov (United States)

Patel-King, Ramila S.; Gilberti, Renée M.; Hom, Erik F. Y.; King, Stephen M.

2013-01-01

Retrograde intraflagellar transport (IFT) is required for assembly of cilia. We identify a Chlamydomonas flagellar protein (flagellar-associated protein 163 [FAP163]) as being closely related to the D1bIC(FAP133) intermediate chain (IC) of the dynein that powers this movement. Biochemical analysis revealed that FAP163 is present in the flagellar matrix and is actively trafficked by IFT. Furthermore, FAP163 copurified with D1bIC(FAP133) and the LC8 dynein light chain, indicating that it is an integral component of the retrograde IFT dynein. To assess the functional role of FAP163, we generated an RNA interference knockdown of the orthologous protein (WD60) in planaria. The Smed-wd60(RNAi) animals had a severe ciliary assembly defect that dramatically compromised whole-organism motility. Most cilia were present as short stubs that had accumulated large quantities of IFT particle–like material between the doublet microtubules and the membrane. The few remaining approximately full-length cilia had a chaotic beat with a frequency reduced from 24 to ∼10 Hz. Thus WD60/FAP163 is a dynein IC that is absolutely required for retrograde IFT and ciliary assembly. PMID:23864713

Navy Force Structure and Shipbuilding Plans: Background and Issues for Congress

Science.gov (United States)

2016-03-17

industrial base. Detailed coverage of certain individual Navy shipbuilding programs can be found in the following CRS reports:  CRS Report RS20643...U.S. Offset Strategy and its Implications for Partners and Allies, As Delivered by Deputy Secretary of Defense Bob Work, Willard Hotel , January 28...Contracting in Defense Acquisition : Background and Issues for Congress, by Ronald O’Rourke and Moshe Schwartz. Navy Force Structure and Shipbuilding Plans

Canada`s green plan and the earth summit

Energy Technology Data Exchange (ETDEWEB)

NONE

1993-12-31

In June 1992 one of the largest international conferences ever held took place in Rio de Janeiro, Brazil. It was attended by the heads of state of more than 100 countries. The ambitious aim of the United Nations Conference on Environment and Development (UNCED) -- the Earth Summit -- was to try to reconcile the need for global environmental protection with the need for continuing economic development. The purpose of this document is to provide a brief account of the results of Rio and the way Canadians participated. In addition, this document outlines the immediate priorities of the Government of Canada and the actions under way. It is not meant to be a comprehensive response to the entire Rio agenda. Rather, it is intended to report to Canadians on the steps the government has taken so far and, where possible, the direction in which it is headed. On the number of important issues, the government`s plans are well advanced. For example, action is well under way on the Convention on Climate Change, as high-lighted in the Green Plan`s National Action Strategy on Global Warming. On a number of other issues, it is clear that there is work to be done. The government is committed to completing the task through continuing action and leadership.

Program plan for the resolution of tank vapor issues

International Nuclear Information System (INIS)

Osborne, J.W.

1992-09-01

The purpose of this document is to provide a detailed description of the priorities, logic, work breakdown structure (WBS), task descriptions, and program milestones required for the resolution of tank vapor issues associated with the single-shell tanks (SST) and double-shell tanks (DST). The primary objective of this plan is to determine whether a health (personnel exposure) and/or safety (flammability) hazard exists. This plan is focused upon one waste tank, 241-C-103, but contains all elements required to bring the vapor issues to resolution

PFP issues/assumptions development and management planning guide

International Nuclear Information System (INIS)

SINCLAIR, J.C.

1999-01-01

The PFP Issues/Assumptions Development and Management Planning Guide presents the strategy and process used for the identification, allocation, and maintenance of an Issues/Assumptions Management List for the Plutonium Finishing Plant (PFP) integrated project baseline. Revisions to this document will include, as attachments, the most recent version of the Issues/Assumptions Management List, both open and current issues/assumptions (Appendix A), and closed or historical issues/assumptions (Appendix B). This document is intended be a Project-owned management tool. As such, this document will periodically require revisions resulting from improvements of the information, processes, and techniques as now described. Revisions that suggest improved processes will only require PFP management approval

Status of safety issues at licensed power plants: TMI Action Plan requirements, unresolved safety issues, generic safety issues, other multiplant action issues. Supplement 4

International Nuclear Information System (INIS)

1994-12-01

As part of ongoing US Nuclear Regulatory Commission (NRC) efforts to ensure the quality and accountability of safety issue information, the NRC established a program for publishing an annual report on the status of licensee implementation and NRC verification of safety issues in major NRC requirements areas. This information was initially compiled and reported in three NUREG-series volumes. Volume 1, published in March 1991, addressed the status of Three Mile Island (TMI) Action Plan Requirements. Volume 2, published in May 1991, addressed the status of unresolved safety issues (USIs). Volume 3, published in June 1991, addressed the implementation and verification status of generic safety issues (GSIs). The first annual supplement, which combined these volumes into a single report and presented updated information as of September 30, 1991, was published in December 1991. The second annual supplement, which provided updated information as of September 30, 1992, was published in December 1992. Supplement 2 also provided the status of licensee implementation and NRC verification of other multiplant action (MPA) issues not related to TMI Action Plan requirements, USIs, or GSIs. Supplement 3 gives status as of September 30, 1993. This annual report, Supplement 4, presents updated information as of September 30, 1994. This report gives a comprehensive description of the implementation and verification status of TMI Action Plan requirements, safety issues designated as USIs, GSIs, and other MPAs that have been resolved and involve implementation of an action or actions by licensees. This report makes the information available to other interested parties, including the public. Additionally, this report serves as a follow-on to NUREG-0933, ''A Prioritization of Generic Safety Issues,'' which tracks safety issues until requirements are approved for imposition at licensed plants or until the NRC issues a request for action by licensees

Identification of histone H4-like TAF in Schizosaccharomyces pombe as a protein that interacts with WD repeat-containing TAF

OpenAIRE

Mitsuzawa, Hiroshi; Ishihama, Akira

2002-01-01

The general transcription factor TFIID consists of the TATA-binding protein (TBP) and multiple TBP-associated factors (TAFs). We previously identified two distinct WD repeat-containing TAFs, spTAF72 and spTAF73, in the fission yeast Schizosaccharomyces pombe. Here we report the identification of another S.pombe TAF, spTAF50, which is the S.pombe homolog of histone H4-like TAFs such as human TAF80, Drosophila TAF60 and Saccharomyces cerevisiae TAF60. spTAF50 was identified in a two-hybrid scre...

222-S Laboratory Quality Assurance Plan. Revision 1

International Nuclear Information System (INIS)

Meznarich, H.K.

1995-01-01

This Quality Assurance Plan provides,quality assurance (QA) guidance, regulatory QA requirements (e.g., 10 CFR 830.120), and quality control (QC) specifications for analytical service. This document follows the U.S Department of Energy (DOE) issued Hanford Analytical Services Quality Assurance Plan (HASQAP). In addition, this document meets the objectives of the Quality Assurance Program provided in the WHC-CM-4-2, Section 2.1. Quality assurance elements required in the Guidelines and Specifications for Preparing Quality Assurance Program Plans (QAMS-004) and Interim Guidelines and Specifications for Preparing Quality Assurance Project Plans (QAMS-005) from the US Environmental Protection Agency (EPA) are covered throughout this document. A quality assurance index is provided in the Appendix A. This document also provides and/or identifies the procedural information that governs laboratory operations. The personnel of the 222-S Laboratory and the Standards Laboratory including managers, analysts, QA/QC staff, auditors, and support staff shall use this document as guidance and instructions for their operational and quality assurance activities. Other organizations that conduct activities described in this document for the 222-S Laboratory shall follow this QA/QC document

Integrating Gender Issues in Recovery and Reconstruction Planning

OpenAIRE

World Bank

2011-01-01

This note on integrating gender issues in recovery and reconstruction planning is the fifth in a series of guidance notes on gender issues in Disaster Risk Management (DRM) in East Asia and Pacific region. There are number of key challenges that women face in different elements of post disaster risk reconstruction and recovery. This note addresses the following bottlenecks: a) housing, lan...

Status of safety issues at licensed power plants: TMI Action Plan requirements, unresolved safety issues, generic safety issues, other multiplant action issues

International Nuclear Information System (INIS)

1992-12-01

This report is to provide a comprehensive description of the implementation and verification status of Three Mile Island (TMI) Action Plan requirements, safety issues designated as Unresolved Safety Issues (USIs), Generic Safety Issues(GSIs), and other Multiplant Actions (MPAs) that have been resolved and involve implementation of an action or actions by licensees. This report makes the information available to other interested parties, including the public. An additional purpose of this NUREG report is to serve as a follow-on to NUREG-0933, ''A Prioritization of Generic Safety Issues,'' which tracks safety issues up until requirements are approved for imposition at licensed plants or until the NRC issues a request for action by licensees

Status of safety issues at licensed power plants: TMI action plan requirements, unresolved safety issues, generic safety issues

International Nuclear Information System (INIS)

1991-12-01

As part of ongoing US Nuclear Regulatory Commission (NRC) efforts to ensure the quality and accountability of safety issue information, a program was established whereby an annual NUREG report would be published on the status of licensee implementation and NRC verification of safety issues in major NRC requirements areas. This information was compiled and reported in three NUREG volumes. Volume 1, published in March 1991, addressed the status of of Three Mile Island (TMI) Action Plan Requirements. Volume 2, published in May 1991, addressed the status of unresolved safety issues (USIs). Volume 3, published in June 1991, addressed the implementation and verification status of generic safety issues (GSIs). This annual NUREG report combines these volumes into a single report and provides updated information as of September 30, 1991. The data contained in these NUREG reports are a product of the NRC's Safety Issues Management System (SIMS) database, which is maintained by the Project Management Staff in the Office of Nuclear Reactor Regulation and by NRC regional personnel. This report is to provide a comprehensive description of the implementation and verification status of TMI Action Plan Requirements, safety issues designated as USIs, and GSIs that have been resolved and involve implementation of an action or actions by licensees. This report makes the information available to other interested parties, including the public. An additional purpose of this NUREG report is to serve as a follow-on to NUREG-0933, ''A Prioritization of Generic Safety Issues,'' which tracks safety issues up until requirements are approved for imposition at licensed plants or until the NRC issues a request for action by licensees

Resource planning for gas utilities: Using a model to analyze pivotal issues

Energy Technology Data Exchange (ETDEWEB)

Busch, J.F.; Comnes, G.A.

1995-11-01

With the advent of wellhead price decontrols that began in the late 1970s and the development of open access pipelines in the 1980s and 90s, gas local distribution companies (LDCs) now have increased responsibility for their gas supplies and face an increasingly complex array of supply and capacity choices. Heretofore this responsibility had been share with the interstate pipelines that provide bundled firm gas supplies. Moreover, gas supply an deliverability (capacity) options have multiplied as the pipeline network becomes increasing interconnected and as new storage projects are developed. There is now a fully-functioning financial market for commodity price hedging instruments and, on interstate Pipelines, secondary market (called capacity release) now exists. As a result of these changes in the natural gas industry, interest in resource planning and computer modeling tools for LDCs is increasing. Although in some ways the planning time horizon has become shorter for the gas LDC, the responsibility conferred to the LDC and complexity of the planning problem has increased. We examine current gas resource planning issues in the wake of the Federal Energy Regulatory Commission`s (FERC) Order 636. Our goal is twofold: (1) to illustrate the types of resource planning methods and models used in the industry and (2) to illustrate some of the key tradeoffs among types of resources, reliability, and system costs. To assist us, we utilize a commercially-available dispatch and resource planning model and examine four types of resource planning problems: the evaluation of new storage resources, the evaluation of buyback contracts, the computation of avoided costs, and the optimal tradeoff between reliability and system costs. To make the illustration of methods meaningful yet tractable, we developed a prototype LDC and used it for the majority of our analysis.

Major issues on establishing an emergency plan in nuclear facilities

International Nuclear Information System (INIS)

Chen, Zhu-zhou

1988-03-01

Several major issues on emergency planning and preparation in nuclear facilities were discussed -- such as the importance of emergency planning and preparation, basic principles of intervention and implementation of emergency plan and emergency training and drills to insure the effectiveness of the emergency plan. It is emphasized that the major key point of emergency planning and response is to avoid the occurrence of serious nonrandom effect. 12 refs., 3 tabs

Analysis of heterogeneous gallstones using laser-induced breakdown spectroscopy (LIBS) and wavelength dispersive X-ray fluorescence (WD-XRF).

Science.gov (United States)

Jaswal, Brij Bir S; Kumar, Vinay; Sharma, Jitendra; Rai, Pradeep K; Gondal, Mohammed A; Gondal, Bilal; Singh, Vivek K

2016-04-01

Laser-induced breakdown spectroscopy (LIBS) is an emerging analytical technique with numerous advantages such as rapidity, multi-elemental analysis, no specific sample preparation requirements, non-destructiveness, and versatility. It has been proven to be a robust elemental analysis tool attracting interest because of being applied to a wide range of materials including biomaterials. In this paper, we have performed spectroscopic studies on gallstones which are heterogeneous in nature using LIBS and wavelength dispersive X-ray fluorescence (WD-XRF) techniques. It has been observed that the presence and relative concentrations of trace elements in different kind of gallstones (cholesterol and pigment gallstones) can easily be determined using LIBS technique. From the experiments carried out on gallstones for trace elemental mapping and detection, it was found that LIBS is a robust tool for such biomedical applications. The stone samples studied in the present paper were classified using the Fourier transform infrared (FTIR) spectroscopy. WD-XRF spectroscopy has been applied for the qualitative and quantitative analysis of major and trace elements present in the gallstone which was compared with the LIBS data. The results obtained in the present paper show interesting prospects for LIBS and WD-XRF to study cholelithiasis better.

Implementation Issues for Departure Planning Systems

Science.gov (United States)

Hansman, R. John; Feron, Eric; Clarke, John-Paul; Odoni, Amedeo

1999-01-01

The objective of the proposed effort is to investigate issues associated with the design and implementation of decision aiding tools to assist in improving the departure process at congested airports. This effort follows a preliminary investigation of potential Departure Planning approaches and strategies, which identified potential benefits in departure efficiency, and also in reducing the environmental impact of aircraft in the departure queue. The preliminary study bas based, in large part, on observations and analysis of departure processes at Boston, Logan airport. The objective of this follow-on effort is to address key implementation issues and to expand the observational base to include airports with different constraints and traffic demand. Specifically, the objectives of this research are to: (1) Expand the observational base to include airports with different underlying operational dynamics. (2) Develop prototype decision aiding algorithms/approaches and assess potential benefits. and (3) Investigate Human Machine Integration (HMI) issues associated with decision aids in tower environments.

Safety issue resolution strategy plan for inactive miscellaneous underground storage tanks

International Nuclear Information System (INIS)

Wang, O.S.; Powers, T.B.

1994-09-01

The purpose of this strategy plan is to identify, confirm, and resolve safely issues associated with inactive miscellaneous underground storage tanks (MUSTs) using a risk-based priority approach. Assumptions and processes to assess potential risks and operational concerns are documented in this report. Safety issue priorities are ranked based on a number of considerations including risk ranking and cost effectiveness. This plan specifies work scope and recommends schedules for activities related to resolving safety issues, such as collecting historical data, searching for authorization documents, performing Unreviewed Safety Question (USQ) screening and evaluation, identifying safety issues, imposing operational controls and monitoring, characterizing waste contents, mitigating and resolving safety issues, and fulfilling other remediation requirements consistent with the overall Tank Waste Remediation System strategy. Recommendations for characterization and remediation are also recommended according to the order of importance and practical programmatic consideration

Issues Facing Pharmacy Leaders in 2015: Suggestions for Pharmacy Strategic Planning

Science.gov (United States)

Weber, Robert J.

2015-01-01

Issues facing pharmacy leaders in 2015 include practice model growth and the role of pharmacy students, clinical privileging of health-system pharmacists and provider status, medication error prevention, and specialty pharmacy services. The goal of this article is to provide practical approaches to 4 issues facing pharmacy leaders in 2015 to help them focus their department’s goals. This article will address (1) advances in the pharmacy practice model initiative and the role of pharmacy students, (2) the current thinking of pharmacists being granted clinical privileges in health systems, (3) updates on preventing harmful medication errors, and (4) the growth of specialty pharmacy services. The sample template of a strategic plan may be used by a pharmacy department in 2015 in an effort to continue developing patient-centered pharmacy services. PMID:25717212

Issues for the 1990s.

Science.gov (United States)

Weiner, Edith; Brown, Arnold

1986-01-01

Discussed are the issues now emerging that seem likely to dominate thinking, planning, and decision-making in the United States and elsewhere during the next decade. These include campus unrest, China as a world economic force, controlling health-care, birth defects, role of the computer in education, and human language/computer language. (RM)

Unilateral rubral tremors in Wilson′s disease treated with dimercaprol

Directory of Open Access Journals (Sweden)

Rahul T Chakor

2015-01-01

Full Text Available Tremors are reported as the most frequent neurological manifestation of Wilson′s disease (WD in some series. Postural tremors, rest tremors, action tremors and wing-beating (rubral tremors are the different types of tremors seen in WD. We report a patient of WD with unilateral rubral tremors refractory to 1-year therapy with Penicillamine and anti-tremor medications. The tremors decreased considerably after adding chelation therapy with dimercaprol. Combination of Penicillamine and dimercaprol is an effective decoppering measure in rubral tremors of WD.

A pomegranate (Punica granatum L.) WD40-repeat gene is a functional homologue of Arabidopsis TTG1 and is involved in the regulation of anthocyanin biosynthesis during pomegranate fruit development.

Science.gov (United States)

Ben-Simhon, Zohar; Judeinstein, Sylvie; Nadler-Hassar, Talia; Trainin, Taly; Bar-Ya'akov, Irit; Borochov-Neori, Hamutal; Holland, Doron

2011-11-01

Anthocyanins are the major pigments responsible for the pomegranate (Punica granatum L.) fruit skin color. The high variability in fruit external color in pomegranate cultivars reflects variations in anthocyanin composition. To identify genes involved in the regulation of anthocyanin biosynthesis pathway in the pomegranate fruit skin we have isolated, expressed and characterized the pomegranate homologue of the Arabidopsis thaliana TRANSPARENT TESTA GLABRA1 (TTG1), encoding a WD40-repeat protein. The TTG1 protein is a regulator of anthocyanins and proanthocyanidins (PAs) biosynthesis in Arabidopsis, and acts by the formation of a transcriptional regulatory complex with two other regulatory proteins: bHLH and MYB. Our results reveal that the pomegranate gene, designated PgWD40, recovered the anthocyanin, PAs, trichome and seed coat mucilage phenotype in Arabidopsis ttg1 mutant. PgWD40 expression and anthocyanin composition in the skin were analyzed during pomegranate fruit development, in two accessions that differ in skin color intensity and timing of appearance. The results indicate high positive correlation between the total cyanidin derivatives quantity (red pigments) and the expression level of PgWD40. Furthermore, strong correlation was found between the steady state levels of PgWD40 transcripts and the transcripts of pomegranate homologues of the structural genes PgDFR and PgLDOX. PgWD40, PgDFR and PgLDOX expression also correlated with the expression of pomegranate homologues of the regulatory genes PgAn1 (bHLH) and PgAn2 (MYB). On the basis of our results we propose that PgWD40 is involved in the regulation of anthocyanin biosynthesis during pomegranate fruit development and that expression of PgWD40, PgAn1 and PgAn2 in the pomegranate fruit skin is required to regulate the expression of downstream structural genes involved in the anthocyanin biosynthesis.

The site-characterization plan and its role in resolving siting and licensing issues

International Nuclear Information System (INIS)

Hanlon, C.L.

1986-01-01

As required by the Nuclear Waste Policy Act and the Nuclear Regulatory Commission (NRC) in 10 CFR Part 60, the Department of Energy is preparing plans for conducting site characterization at three candidate sites. Prepared according to a detailed annotated outline that is based on the NRC's Regulatory Guide 4.17, these plans will present the information collected to date about the geologic, hydrologic, geochemical, geoengineering, and climatic conditions of each site; describe the design of the repository and the waste package; and discuss the site-characterization program. The most important portions of the plan will be the strategy for resolving siting and licensing issues and the description of the testing and analysis program to be followed in resolving these issues. The issues-resolution strategy consists of identifying issues and the associated information needs; allocating performance goals for various components of the repository system; developing a testing plan to gather the necessary information; gathering and analyzing the information; and documenting the results for use in site selection and licensing. The issues-resolution strategy will allow the Department to define all of the issues that must be resolved in order to demonstrate compliance with applicable regulations and to specify the information needed to resolve these issues. It will provide a consistent framework and establish priorities for the Department's site-characterization effort for the next several years

The Norwegian Plan of Action for nuclear safety issues

International Nuclear Information System (INIS)

1997-07-01

The Plan of Action underlies Norwegian activities in the field of international co-operation to enhance nuclear safety and prevent radioactive contamination from activities in Eastern Europe and the former Soviet Union. Geographically the highest priority has been given to support for safety measures in north-west Russia. This information brochure outlines the main content of the Plan of Action for nuclear safety issues and lists a number of associated measures and projects

The Norwegian Plan of Action for nuclear safety issues

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-07-01

The Plan of Action underlies Norwegian activities in the field of international co-operation to enhance nuclear safety and prevent radioactive contamination from activities in Eastern Europe and the former Soviet Union. Geographically the highest priority has been given to support for safety measures in north-west Russia. This information brochure outlines the main content of the Plan of Action for nuclear safety issues and lists a number of associated measures and projects.

Bipolar disorders and Wilson’s disease

Directory of Open Access Journals (Sweden)

Carta Mauro

2012-05-01

Full Text Available Abstract Background The aim of this study was to determine the risk for Bipolar Disorder (BD in Wilson’s disease (WD and to measure the impaired Quality of Life (QL in BD with WD using standardized psychiatric diagnostic tools and a case control design. Methods This was a case control study. The cases were 23 consecutive patients with WD treated at the University Hospital in Cagliari, Italy, and the controls were 92 sex- and age-matched subjects with no diagnosis of WD who were randomly selected from a database used previously for an epidemiological study. Psychiatric diagnoses according to DSM-IV criteria were determined by physicians using structured interview tools (ANTAS-SCID. QL was measured by means of SF-12. Results Compared to controls, WD patients had lower scores on the SF-12 and higher lifetime prevalence of DSM-IV major depressive disorders (OR = 5.7, 95% CI 2.4–17.3 and bipolar disorders (OR = 12.9, 95% CI 3.6–46.3. BD was associated with lower SF-12 in WD patients. Conclusions This study was the first to show an association between BD and WD using standardized diagnostic tools and a case control design. Reports in the literature about increased schizophrenia-like psychosis in WD and a lack of association with bipolar disorders may thus have been based on a more inclusive diagnosis of schizophrenia in the past. Our findings may explain the frequent reports of loss of emotional control, hyperactivity, loss of sexual inhibition, and irritability in WD patients. This study was limited by a small sample size.

Estimation of a stress field in the earth`s crust using drilling-induced tensile fractures observed at well WD-1 in the Kakkonda geothermal field; Kakkonda WD-1 sei de kansokusareta drilling induced tensile fracture ni yoru chikaku oryokuba no suitei

Energy Technology Data Exchange (ETDEWEB)

Okabe, T. [GERD Geothermal Energy Research and Development Co. Ltd., Tokyo (Japan); Hayashi, K. [Tohoku Univ., Sendai (Japan). Inst. of Fluid Science; Kato, O.; Doi, N.; Miyazaki, S. [Japan Metals and Chemicals Co. Ltd., Tokyo (Japan); Uchida, T. [New Energy and Industrial Technology Development Organization, Tokyo, (Japan)

1997-05-27

This paper describes estimation of a stress field in the earth`s crust in the Kakkonda geothermal field. Formation micro imager (FMI) logging known as a crack detecting logging was performed in the well WD-1. This FMI logging has made observation possible on cracks along well axis thought to indicate size and direction of the crust stress, and drilling-induced tensile fractures (DTF). It was verified that these DTFs are generated initially in an azimuth determined by in-situ stress (an angle up to the DTF as measured counterclockwise with due north as a starting point, expressed in {theta}) in the well`s circumferential direction. It was also confirmed that a large number of cracks incline at a certain angle to the well axis (an angle made by the well axis and the DTF, expressed in {gamma}). The DTF is a crack initially generated on well walls as a result of such tensile stresses as mud pressure and thermal stress acting on the well walls during well excavation, caused by the in-situ stress field. Measurement was made on the {theta} and {gamma} from the FMI logging result, and estimation was given on a three-dimensional stress field. Elucidating the three-dimensional crust stress field in a geothermal reservoir is important in making clear the formation mechanism thereof and the growth of water-permeable cracks. This method can be regarded as an effective method. 9 refs., 8 figs., 1 tab.

The Online Catalog: Issues in Planning and Development.

Science.gov (United States)

Richards, Timothy F.

1984-01-01

Discusses key issues to be addressed in planning for introduction of online public access catalog in academic research library environment. Purpose of catalog, reasons to adopt catalog, user behavior, use of catalog records, authority control, shared or unique systems, and impact on staff are highlighted. Seventy-three sources are cited. (EJS)

Wilson’s disease presenting with HELLP syndrome; A case report

Directory of Open Access Journals (Sweden)

Sümeyra Nergiz Avcıoğlu

2015-03-01

Full Text Available Wilson’s disease (WD is an autosomal recessive disorder. It is characterized by toxic accumulation of copper mainly in the liver and brain but also in cornea and kidney due to a defect in biliary excretion of copper. The hepatic manifestation of WD is diverse and may include asymptomatic elevation of aminotransferase, chronic hepatitis, cirrhosis, or acute/fulminant hepatic failure. Characteristic of acute hepatic failure in WD is concomitance of acute intravascular hemolytic anemia. Acute intravascular hemolytic anemia and thrombocytopenia in WD may be interpreted as a feature of Hemolysis, Elevated Liver Enzymes, Low Platelet Count (HELLP syndrome besides acute liver failure. The differential diagnosis may be very difficult. Here, WD in pregnancy presenting with clinical symptoms of HELLP syndrome and developing acute liver failure in postpartum period is discussed.

Strategic plan for science-U.S. Geological Survey, Ohio Water Science Center, 2010-15

Science.gov (United States)

,

2010-01-01

This Science Plan identifies specific scientific and technical programmatic issues of current importance to Ohio and the Nation. An examination of those issues yielded a set of five major focus areas with associated science goals and strategies that the Ohio Water Science Center will emphasize in its program during 2010-15. A primary goal of the Science Plan is to establish a relevant multidisciplinary scientific and technical program that generates high-quality products that meet or exceed the expectations of our partners while supporting the goals and initiatives of the U.S. Geological Survey. The Science Plan will be used to set the direction of new and existing programs and will influence future training and hiring decisions by the Ohio Water Science Center.

Effects of disrupting the polyketide synthase gene WdPKS1 in Wangiella [Exophiala] dermatitidis on melanin production and resistance to killing by antifungal compounds, enzymatic degradation, and extremes in temperature

Directory of Open Access Journals (Sweden)

Mandal Piyali

2006-06-01

Full Text Available Abstract Background Wangiella dermatitidis is a human pathogenic fungus that is an etiologic agent of phaeohyphomycosis. W. dermatitidis produces a black pigment that has been identified as a dihydroxynaphthalene melanin and the production of this pigment is associated with its virulence. Cell wall pigmentation in W. dermatitidis depends on the WdPKS1 gene, which encodes a polyketide synthase required for generating the key precursor for dihydroxynaphthalene melanin biosynthesis. Results We analyzed the effects of disrupting WdPKS1 on dihydroxynaphthalene melanin production and resistance to antifungal compounds. Transmission electron microscopy revealed that wdpks1Δ-1 yeast had thinner cell walls that lacked an electron-opaque layer compared to wild-type cells. However, digestion of the wdpks1Δ-1 yeast revealed small black particles that were consistent with a melanin-like compound, because they were acid-resistant, reacted with melanin-binding antibody, and demonstrated a free radical signature by electron spin resonance analysis. Despite lacking the WdPKS1 gene, the mutant yeast were capable of catalyzing the formation of melanin from L-3,4-dihyroxyphenylalanine. The wdpks1Δ-1 cells were significantly more susceptible to killing by voriconazole, amphotericin B, NP-1 [a microbicidal peptide], heat and cold, and lysing enzymes than the heavily melanized parental or complemented strains. Conclusion In summary, W. dermatitidis makes WdPKS-dependent and -independent melanins, and the WdPKS1-dependent deposition of melanin in the cell wall confers protection against antifungal agents and environmental stresses. The biological role of the WdPKS-independent melanin remains unclear.

ALWR severe accident issue resolution in support of updated emergency planning

International Nuclear Information System (INIS)

Additon, Stephen L.; Leaver, David E.; Sorrell, Steven W.; Theofanous, Theo G.

2004-01-01

. The severe accident risk characteristics of the ALWRs reflect an emphasis on accident prevention, which is quantified in the URD as a maximum permissible core damage frequency of less than one occurrence in 100,000 reactor years. For severe accident sequences of a frequency lower than this criterion, the URD safety policy requires provisions to arrest, mitigate, and contain the accident and, accordingly, opportunities to terminate a core melt sequence are provided whenever practical at every stage of core degradation. This includes design provisions to maximize the chances of success for reflooding the reactor by depressurizing the primary system, provisions to ensure retention of core debris in the reactor vessel by cooling the outside of the reactor vessel, and provisions for a more favorable geometry for core debris cooling in the reactor cavity in order to slow and then terminate a core-concrete interaction. For all risk-significant branches of the containment event tree, it must be demonstrated that early containment failure is avoided. This paper addresses the severe accident issue resolution tasks which were undertaken by the U.S. ALWR Program and ARSAP to ensure that the capability of passive ALWRs to arrest, mitigate and contain severe accidents would be sufficient to justify a significant change in the appropriate emergency planning requirements. The next section summarizes all of the issue resolution activities that will culminate in the issuance by the U.S. Nuclear Regulatory Commission (NRC) of a Final Safety Evaluation Report for the passive ALWR URD, scheduled for January 1994. The following section addresses more recent activities undertaken by ARSAP to enhance the issue resolution basis and to provide additional confirmatory evidence supporting the URD criteria. Included are the ongoing activities to establish a technical case, if possible, for in-vessel retention for the passive PWR and for the accommodation of ex-vessel steam explosions in the

The Capacity to Integrate and Deal with Environmental Issues in Local Transport Policy and Planning

DEFF Research Database (Denmark)

Hansen, Carsten Jahn

2002-01-01

The article identifies and discuss the capacity to integrate and deal with environmental issues in local transport policy-making and planning processes.......The article identifies and discuss the capacity to integrate and deal with environmental issues in local transport policy-making and planning processes....

Spectroscopic Evolution of Disintegrating Planetesimals: Minute to Month Variability in the Circumstellar Gas Associated with WD 1145+017

Energy Technology Data Exchange (ETDEWEB)

Redfield, Seth; Cauley, P. Wilson; Duvvuri, Girish M. [Astronomy Department and Van Vleck Observatory, Wesleyan University, Middletown, CT 06459 (United States); Farihi, Jay [Department of Physics and Astronomy, University College London, London WC1E 6BT (United Kingdom); Parsons, Steven G. [Department of Physics and Astronomy, University of Sheffield, Sheffield, S3 7RH (United Kingdom); Gänsicke, Boris T., E-mail: sredfield@wesleyan.edu [Department of Physics, University of Warwick, Coventry CV4 7AL (United Kingdom)

2017-04-10

With the recent discovery of transiting planetary material around WD 1145+017, a critical target has been identified that links the evolution of planetary systems with debris disks and their accretion onto the star. We present a series of observations, five epochs over a year, taken with Keck and the VLT, which for the first time show variability of circumstellar absorption in the gas disk surrounding WD 1145+017 on timescales of minutes to months. Circumstellar absorption is measured in more than 250 lines of 14 ions among 10 different elements associated with planetary composition, e.g., O, Mg, Ca, Ti, Cr, Mn, Fe, and Ni. Broad circumstellar gas absorption with a velocity spread of 225 km s{sup −1} is detected, but over the course of a year blueshifted absorption disappears, while redshifted absorption systematically increases. A correlation of equivalent width and oscillator strength indicates that the gas is not highly optically thick (median τ ≈ 2). We discuss simple models of an eccentric disk coupled with magnetospheric accretion to explain the basic observed characteristics of these high-resolution and high signal-to-noise observations. Variability is detected on timescales of minutes in the two most recent observations, showing a loss of redshifted absorption for tens of minutes, coincident with major transit events and consistent with gas hidden behind opaque transiting material. This system currently presents a unique opportunity to learn how the gas causing the spectroscopic, circumstellar absorption is associated with the ongoing accretion evidenced by photospheric contamination, as well as the transiting planetary material detected in photometric observations.

[Haikou issues circular on planned parenthood].

Science.gov (United States)

1981-02-03

The Organization Department of the Haikou Municipal CCP Committee, the municipal grain, finance, commerce, education bureau, personnel, public security, labor, civil affairs, public health, and housing bureaus, supply and marketing cooperative, and planned parenthood office recently issued a joint circular on implementing the provincial planned parenthood regulations. The circular demanded that the marriage registration and census system be seriously implemented. When people are registering for marriage, we must teach them to have only 1 child. We must give priority in housing and employment to an only child and his parents. When commercial, supply, and marketing departments are distributing coupons for fuel, and nonstaple food, they should supply a double amount to the only child. We must carry out serious health care for an only child and give them regular physical check-ups. When they are ill, hospitals should give them priority in registration, treatment, reservation of beds and medicines. The circular reiterated: We must seriously implement the stipulations on rewards and punishments contained in the provincial planned parenthood regulations. Cadres, staff, or workers who apply to have only 1 child must be given lump sums in addition to enjoying the relevant rewards stipulated by the regulations. Cadres, staff, workers, inhabitants, and commune workers who depend on state grain who violate the regulations must be punished according to the regulation. As for those who have 3 or more than 3 children, a 2nd child without planning, or an illegitimate child, the child's grain ration will be sold at negotiated price up to the age of 14. The grain department will distribute to them a supply ticket for negotiated price grain to buy grain in assigned grain shops. full text

Strategic Planning in U.S. Municipalities

Directory of Open Access Journals (Sweden)

James VAN RAVENSWAY

2015-12-01

Full Text Available Strategic planning started in the U.S. as a corporate planning endeavor. By the 1960’s, it had become a major corporate management tool in the Fortune 500. At fi rst, it was seen as a way of interweaving policies, values and purposes with management, resources and market information in a way that held the organization together. By the 1950’s, the concept was simplifi ed somewhat to focus on SWOT as a way of keeping the corporation afl oat in a more turbulent world. The public sector has been under pressure for a long time to become more effi cient, effective and responsive. Many have felt that the adoption of business practices would help to accomplish that. One tool borrowed from business has been strategic planning. At the local government level, strategic planning became popular starting in the 1980’s, and the community’s planning offi ce was called on to lead the endeavor. The planning offi ce was often the advocate of the process. Urban planning offi ces had been doing long-range plans for decades, but with accelerating urban change a more rapid action-oriented response was desired. The paper describes this history and process in the East Lansing, Michigan, U.S., where comprehensive community plans are the result of a multi-year visioning process and call for action- oriented, strategies for targeted parts of the community.

I support renewable energy but : significant planning issues for wind turbines

Energy Technology Data Exchange (ETDEWEB)

Pausner, J [County of Grey, ON (Canada)

2004-07-01

This PowerPoint presentation examined the wind power project of Blue Highlands, located in Eastern Grey County, Ontario. The project, for which no approval has yet been obtained, involves 67 turbines (120-130 MW). The staff of the Niagara Escarpment Commission (NEC) has made the following recommendations concerning wind energy development projects: (1) the Niagara Escarpment Plan should not be the focus of large-scale industrial type wind power development, (2) wind power developments should be allowed only in certain portions of the Plan area, (3) permission may be granted for household or farm generators throughout the Plan, on a case-by-case basis, (4) the NEC should review proposals adjacent to Plan boundaries which may have a visual impact, and (5) conduct further reviews after major parks are constructed elsewhere. The author identified important planning issues such as environmental impacts, visual impacts, and noise. Policy implementation through zoning is dependent on defining terms and establishing requirements for setbacks, signage, accessory structures and facilities, height maximums, decommissioning provisions, and site planning. The author discussed data collection and dissemination, as well as mapping. The presentation concluded with proposals for policy development, where the author argued that everyone should play their part. Areas with high potential should be examined and development constrained in order to ensure the protection of existing incompatible uses. The public must be involved in locally based projects. Wind theft issue must be addressed. figs.

China-U.S. Trade Issues

National Research Council Canada - National Science Library

Morrison, Wayne M

2005-01-01

.... With a huge population and a rapidly expanding economy, China is becoming a large market for U.S. exporters. Yet, U.S.-China commercial ties have been strained by a number of issues, including a surging...

Issues in Governance, Planning and Coordination. Staff Report No. 8.

Science.gov (United States)

Montana Commission on Post-Secondary Education, Helena.

This brief report consists of a series of observations on governance, planning, and coordination in Montana postsecondary education. It offers an impressionistic overview of three selected issues: the regents and the 1972 Constitution (background, governance, accountability, and legal protection); Governance of Vocational-Technical Centers (the…

Development of Lesson Plans and Student Worksheets Based Socio-Scientific Issues on Pollution Environmental Topic

Science.gov (United States)

Rahayu, S.; Meyliana, M.; Arlingga, A.; Reny, R.; Siahaan, P.; Hernani, H.

2017-09-01

The aim of this study is to develop lesson plans and student worksheets based socio-scientific issues on pollution environmental topic for seventh-grade junior high school students. Environmental pollution topic split into several subtopics namely air pollution, water pollution and soil pollution. The composing of lesson plans were developed based on socio-scientific issues with five stages, namely (1) Motivate; (2) Challenge; (3) Collect scientific evidence; (4) Analyse the evidence; (5) Build knowledge and make connections; and (6) Use evidence. While student worksheets contain articles on socio-scientific issues, practice, and there are a few questions to determine students’ reasoning. The method that is used in this research is research and development (R & D method). Development model used in this study is a model of Plomp that consists of four stages, namely: (1) Initial Research; (2) Design; (3) Realization or Construction; (4) Testing, evaluation and revision; (5) Implementation, while the research was limited to the fourth stage. Lesson plans and student worksheets based on socio-scientific issues was validated through an expert validation. The result showed that lesson plans and student worksheets based socio-scientific issues on pollution theme have a very decent and be able to apply in science classroom.

Material Accounting Issues at the U.S. MOX Fuel Fabrication Facility

International Nuclear Information System (INIS)

Lyman, E.

2015-01-01

The Mixed Oxide Fuel Fabrication Facility (MFFF) is under construction in the United States. The plant is being licenced by the U.S. Nuclear Regulatory Commission (NRC), which as the U.S. SSAC regulates both domestic MC and A and compliance with international safeguards (where applicable). Among the NRC's MC and A requirements for Category I fuel cycle facilities are programmes for item and process monitoring. The NRC also has requirements for timely resolution of alarms and assessment of the validity of alleged thefts. NRC's item monitoring requirement specifies that the operator must be able to verify the 'presence and integrity' of items, with the goal of detecting the loss of items containing 2 kilogrammes of plutonium within certain time periods. The requirements for resolution of alarms and assessment of alleged thefts also generally require some capability to locate and verify items on demand. However, to the extent these regulations mandate that individual items be physically located and verified by hand, they can be difficult (or impossible) to meet for facilities with large numbers of items. The MFFF design was based largely on French facilities that were not subject to similar requirements. Consequently, the applicant proposed a novel item monitoring approach that relies on the data within the plant's computerized inventory and process control systems. This proposal was challenged in July 2010 by intervenors, raising questions such as whether computer systems could be used as the sole means for verification, given the potential for data to be compromised. In February 2014, the NRC's Atomic Safety and Licencing Board issued a decision upholding the applicant's plan, but one of the three judges issued a dissent, citing concern about cyberterrorism. This paper will discuss the issues argued during the hearing and their broader relevance. (author)

The problem involving OPMEs and the health plans contracts: outline and analysis of the issue

Directory of Open Access Journals (Sweden)

MARTINS, Paulo Roberto do Nascimento

2016-06-01

Full Text Available This paper has as its scope to introduce and analyze some of most polemic issues involving the indications of OPMEs within the health plans contracts. During the text, are exhibited normative elements related to this context, as well as some judicial decisions concerning this matter, aiming to defend, with reasonable grounds, that the indication of the patient’s doctor, when choosing prostheses and orthoses, cannot be taken as the unique nor necessarily the best opinion, given the existence of other interests, beyond the patient’s health, that are often in stake as well. At the end, it is explained that, in light of the currently existing regulation in Brazil, in the context of the supplementary health system, to the patient’s doctor is given the authority only to indicate the characteristics of the materials needed, leaving it to the health plans Operators the choice of the brand and the manufacturer. As long as the courts deny these rules, this serious problem will not be solved.

Ademe et Vous. Research Newsletter No. 11, July 2015. Urban planning and climate change: intertwined issues and practices we should reconsider

International Nuclear Information System (INIS)

Varet, Anne; Guignard, Stephanie

2015-07-01

This Research Newsletter, the first in a series of three dedicated to climate change, focuses on the climate change research undertaken with ADEME's support and its relation to urban management, and the results obtained. Content: - urban planning and climate change: intertwined issues and practices we should reconsider; - significant results: climate change adaptation and urban planning: what sorts of challenges should this obligation meet? - meeting: Jacques Comby, climatologist and president of the university Jean Moulin Lyon III, and Emmanuel Acchiardi, deputy director of Ademe's sustainable cities and regions department

Evaluating the Effects of Restraint Systems on 4WD Testing Methodologies: A Collaborative Effort between the NVFEL and ANL

Science.gov (United States)

Testing vehicles for emissions and fuel economy has traditionally been conducted with a single-axle chassis dynamometer. The 2006 SAE All Wheel Drive Symposium cited four wheel drive (4WD) and all wheel drive (AWD) sales as climbing from 20% toward 30% of a motor vehicle mar...

Quality Assurance/Quality Control Issues for Intraoperative Planning and Adaptive Repeat Planning of Image-Guided Prostate Implants

International Nuclear Information System (INIS)

Zaider, Marco; Cohen, Gilad; Meli, Jerome; Rosenfeld, Anatoly B.

2008-01-01

The quality assurance/quality control purpose is this. We design a treatment plan, and we wish to be as certain as reasonably possible that the treatment is delivered as planned. In the case of conventionally planned prostate brachytherapy, implementing to the letter the implantation plan is rarely attainable and therefore can require adaptive replanning (a quality control issue). The reasons for this state of affairs include changes in the prostate shape and volume during implantation and treatment delivery (e.g., edema resolution) and unavoidable inaccuracy in the placement of the seeds in the prostate. As a result, quality-control activities (e.g., the need to monitor-ideally, on the fly-the target and urethral and rectal dosage) must be also addressed

MUTATION ON WD DIPEPTIDE MOTIFS OF THE p48 SUBUNIT OF CHROMATIN ASSEMBLY FACTOR-1 CAUSING VIABILITY AND GROWTH OF DT40 CHICKEN B CELL LINE

Directory of Open Access Journals (Sweden)

Ahyar Ahmad

2010-07-01

Full Text Available Chromatin assembly factor-1 (CAF-1, a protein complex consisting of three subunits, p150, p60, and p48, is highly conserved from yeast to humans and facilitated nucleosome assembly of newly replicated DNA. The p48 subunit, CAF-1p48 (p48, with seven WD (Trp-Asp repeat motifs, is a member of the WD protein family. The immunoprecipitation experiment revealed that ß-propeller structure of p48 was less stringent for it's binding to HDAC-1, but more stringent for its binding to both histones H4 and CAF-1p60 but not to ASF-1, indicating that the proper ß-propeller structure of p48 is essential for the binding to these two proteins histone H4 and CAF-1p60. Complementation experiments, involving missense and truncated mutants of FLAG-tagged p48, revealed that mutations of every of seven WD dipeptide motifs, like both the N-terminal and C-terminal truncated mutations, could not rescue for the tet-induced lethality. These results indicate not only that p48 is essential for the viability of vertebrate cells, although the yeast p48 homolog is nonessential, but also that all the seven WD dipeptide motifs are necessary for the maintenance of the proper structure of p48 that is fundamentally important for cell viability.   Keywords: Chromatin assembly factor-1, complementation experiments, viability

Public Voucher Plans. Trends and Issues.

Science.gov (United States)

Hadderman, Margaret

This document provides an overview of public-school voucher plans. Educational vouchers originated in the 1960s when Milton Friedman argued that vouchers would improve educational efficiency. Parents would receive the equivalent of per-pupil expenditures in the form of vouchers that could then be used at any school, either public and private. But…

Critical Issues in Language and Education Planning in Twenty First Century in South Africa

Science.gov (United States)

Brook Napier, Diane

2011-01-01

Language and education planning issues and democratic policy implementation in the post-apartheid era in South Africa encompass a range of language-related issues and dilemmas that have counterparts in many countries, within the emerging global education system. The issues in South Africa were and continue to be shaped by the historical legacy of…

Discussion and Reflection on Several Core Issues in the Grand Canal Heritage Conservation Planning Under the Background of Application for World Heritage

Directory of Open Access Journals (Sweden)

D. Yao

2015-08-01

Full Text Available At the turn of the century, a series of new heritage concepts have appeared in the area of international cultural heritage protection, such as cultural landscape, cultural route, heritage corridor, heritage canal, which presents the development of people’s recognition of cultural heritage. According to The Operational Guidelines for the Implementation of the World Heritage Convention, management planning must be contained in the material used to apply for world heritage. The State Administration of Cultural Heritage designed the mission and work schedule of China’s Grand Canal conservation planning in 2008. This research will introduce the working system of China’s Grand Canal conservation planning on three levels: city, province and nation. It will also summarize the characteristics of the core technologies in China’s Grand Canal conservation planning, including key issues like the identification of the core characteristic of China’s Grand Canal, value assessment and determination of the protection scope. Through reviewing, thinking and analyzing the previous accomplishments, the research will offer some advices for the similar world heritage conservation planning after.

Gender issues in planning with water

Science.gov (United States)

Bostenaru-Dan, Maria; Olga Gociman, Cristina

2016-04-01

buildings are endangered by demolition. At the same time, for water heritage, women built or are users of remarcable buildings. Some of these, as in case of hazards, need to take gender issues in consideration (ex. bath resorts). These are relevant for urban planning analysis by means of dedicated programmes such as SpaceSyntax. European programmes such as H2020 try to adapt their policies for gender, including in Security calls. In the genderSTE group we worked towards women and water issues in such calls policy, and there are couple of related initiatives as well which will be shown.

Planning for Site Transition to Long-Term Stewardship: Identification of Requirements and Issues

International Nuclear Information System (INIS)

Banaee, J.

2002-01-01

A systematic methodology is presented and applied for the identification of requirements and issues pertaining to the planning for, and transition to, long term stewardship (LTS). The method has been applied to three of the twelve identified LTS functions. The results of the application of the methodology to contaminated and uncontaminated federal real property in those three functions are presented. The issues that could be seen as impediments to the implementation of LTS are also identified for the three areas under consideration. The identified requirements are significant and in some cases complex to implement. It is clear that early and careful planning is required in all circumstances

Planning for Site Transition to Long-Term Stewardship: Identification of Requirements and Issues

Energy Technology Data Exchange (ETDEWEB)

Banaee, J.

2002-05-16

A systematic methodology is presented and applied for the identification of requirements and issues pertaining to the planning for, and transition to, long term stewardship (LTS). The method has been applied to three of the twelve identified LTS functions. The results of the application of the methodology to contaminated and uncontaminated federal real property in those three functions are presented. The issues that could be seen as impediments to the implementation of LTS are also identified for the three areas under consideration. The identified requirements are significant and in some cases complex to implement. It is clear that early and careful planning is required in all circumstances.

Planning for Site Transition to Long-Term Stewardship: Identification of Requirements and Issues

Energy Technology Data Exchange (ETDEWEB)

Banaee, Jila

2002-08-01

A systematic methodology is presented and applied for the identification of requirements and issues pertaining to the planning for, and transition to, long term stewardship (LTS). The method has been applied to three of the twelve identified LTS functions. The results of the application of the methodology to contaminated and uncontaminated federal real property in those three functions are presented. The issues that could be seen as impediments to the implementation of LTS are also identified for the three areas under consideration. The identified requirements are significant and in some cases complex to implement. It is clear that early and careful planning is required in all circumstances.

Issues and dilemmas in preparation and implementation of the spatial plan of the municipality

Directory of Open Access Journals (Sweden)

Maksin Marija

2012-01-01

Full Text Available Disadvantages of the Serbian planning system and dilemmas about the role of spatial planning in Serbia mainly is reflected at the local level of spatial planning. The focus of the spatial plan of the municipality from the strategic to regulatory role has been shifted by the changes of legal basis. In this paper the key issues and dilemmas in the practice of preparation and implementation of the spatial plan of the municipality in Serbia are pointed out. The review of the three key issues of importance for the direct implementation of planning solutions and concepts: identification of the construction zone, the establishment of rules for the protection, arrangement and construction of physical (natural, landscape and functional entities and settlements, and elaboration of arrangement scheme for the settlement are presented. It has still not made clear what the arrangement scheme for the settlement should represent, so that in practice there is wide variety of schemes, usually completely unenforceable. Good examples of arrangement schemes elaboration within spatial plan of the municipality have been presented and analyzed. Suggestions for improving the content of the strategic and regulatory elements of the spatial plan of the municipality, as well as recommendations to the basic content of the arrangement scheme for settlement as a part of this spatial plan are proposed.

Navy Force Structure and Shipbuilding Plans: Background and Issues for Congress

Science.gov (United States)

2017-02-02

international relations and strategy of basic world geographic features such as the size and location of continents, oceans, and individual countries. From...Navy Force Structure and Shipbuilding Plans: Background and Issues for Congress Ronald O’Rourke Specialist in Naval Affairs February 2, 2017...

[Tianjin issues decision on family planning].

Science.gov (United States)

1981-05-08

The Tianjin Municipal People's Government (China) recently issued a decision on family planning issues regarding encouragement of late childbirth and controlling the birth of a 2nd child. The decision indicated that newlyweds who decide to have their 1st child when they are at least 25 years old will be regarded as practicing late childbirth. A total of 34 days will be added to the present 56-day maternity leave for those newlyweds practicing late childbirth. Some prerequisites for having a 2nd child include the following: the 1st child has a nonhereditary deformity; of a newly married couple, for 1 party this is a 1st marriage while the other party has only 1 child from his or her previous marriage; and a married woman who has a medical certificate on sterility issued by medical and health units at or above the district level and has adopted a child with the approval of departments concerned is now allowed to have a 2nd child. To have a 2nd child without official approval is considered as giving birth to an unplanned child. Each parent of an unplanned child has to pay a special levy for 5 years from the day the child is born. If the interval between the 1st child and the 2nd child of a woman is less than 4 years, this woman and her husband will have to pay the special levies for 5 years and will have to pay levies to make up for the deficiencies caused by the insufficient interval between their 1st and 2nd child. Due to the great differences in economic conditions existing in the rural counties, every rural county People's Government may formulate its own stipulations concerning the length and amount of levies in accordance with local conditions.

Dream Recall Frequencies and Dream Content in Wilson’s Disease with and without REM Sleep Behaviour Disorder: A Neurooneirologic Study

Directory of Open Access Journals (Sweden)

Gotthard G. Tribl

2016-01-01

Full Text Available Objective. Violent dream content and its acting out during rapid eye movement sleep are considered distinctive for rapid eye movement sleep behaviour disorder (RBD. This study reports first quantitative data on dreaming in a cohort of patients with treated Wilson’s disease (WD and in patients with WD with RBD. Methods. Retrospective questionnaires on different dimensions of dreaming and a prospective two-week home dream diary with self-rating of emotions and blinded, categorical rating of content by an external judge. Results. WD patients showed a significantly lower dream word count and very few other differences in dream characteristics compared to age- and sex-matched healthy controls. Compared to WD patients without RBD, patients with WD and RBD reported significantly higher nightmare frequencies and more dreams with violent or aggressive content retrospectively; their prospectively collected dream reports contained significantly more negative emotions and aggression. Conclusions. The reduction in dream length might reflect specific cognitive deficits in WD. The lack of differences regarding dream content might be explained by the established successful WD treatment. RBD in WD had a strong impact on dreaming. In accordance with the current definition of RBD, violent, aggressive dream content seems to be a characteristic of RBD also in WD.

U.S.-China Relations: Policy Issues

Science.gov (United States)

2011-01-12

global issues on which the Obama Administration has sought to work with China are the international financial crisis, climate change, and nuclear non-proliferation. In remarks in July 2009, President Obama declared that partnership between the United States and China was a prerequisite for progress on many of the most pressing global challenges. Continuing major bilateral issues in the relationship include trade and...into the Obama Administration, U.S. officials point to some successes in their efforts to work with China on global issues , including

The gender issue in energy project planning. Welfare, empowerment or efficiency?

NARCIS (Netherlands)

Skutsch, Margaret

1998-01-01

The gap between gender policy as adopted by governments and donors, and the inclusion of gender issues in energy planning practice at project level, is great, despite the fact that there are many manuals available which demonstrate how to go about gathering gender-based data and analysing this. This

Current issues and strategies for transmission planning

Energy Technology Data Exchange (ETDEWEB)

Isaacs, A.L. [Electranix, Winnipeg, MB (Canada); Rajapakse, A. [Manitoba Univ., Winnipeg, MB (Canada)

2008-07-01

Following the widespread deregulation of the electric power industry in the early 1990s, significant changes occurred in the regulatory and planning environments of the industry. Several regions of North America remain fully or partially regulated in the traditional sense including most Canadian provinces, except for Alberta and Ontario. Although the Mexican system has separate generation and transmission companies and current restructuring efforts are underway, all companies are state-owned, and private investment in energy is heavily constrained by the Mexican constitution. In these regulated regions, traditional generation and transmission expansion planning methods remain in use. This paper presented an overview of current trends in transmission planning strategies that have evolved in response to the restructuring of the power industry, and a conceptual framework of a procedure that would guide planners faced with the challenges of incorporating large scale wind generation in deregulated environments. The paper provided background information on the effect of deregulation on transmission planning. Planning strategies that were discussed included quantifying risk to help identify best alternatives; use of reference systems to estimate generator costs and reduce uncertainty; project based transmission expansion; transmission construction ahead of generation; and generation ahead of transmission. The impact of wind on transmission planning as well as future work addressing challenges posed by wind were also addressed. Research is continuing in this area to illustrate the concepts proposed through a detailed case study. 15 refs., 2 figs.

Canada`s green plan - The second year. Summary

Energy Technology Data Exchange (ETDEWEB)

NONE

1994-12-31

Canada`s Green Plan is the national strategy and action plan for sustainable development launched by the federal government. The Green Plan`s goal is `to secure for current and future generations a safe and healthy environment and a sound and prosperous economy.` It represents a fundamental shift in the way the federal government views economic development and environmental protection: they are inextricably linked; both are critical to the health and well-being of Canadians. Substantial development has been made in Canada, with advances being made on the Green Plan`s short-term objectives and on our longer term priorities.

State Performance-Based Regulation Using Multiyear Rate Plans for U.S. Electric Utilities

Energy Technology Data Exchange (ETDEWEB)

Lowry, Mark Newton [Pacific Economics Group Research LLC (United States); Makos, Matt [Pacific Economics Group Research LLC (United States); Deason, Jeff [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Schwartz, Lisa [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

2017-07-31

Electric utilities today must contain costs at a time when many need to modernize aging systems and all face major changes in technologies, customer preferences and competitive pressures.Most U.S. electric utility facilities are investor-owned, subject to rate and service regulation by state public utility commissions. Regulatory systems under which these utilities operate affect their performance and ability to meet these challenges. In this business environment, multiyear rate plans have some advantages over traditional rate regulation.The report focuses on key design issues and provides case studies of the multiyear rate plan approach, applicable to both vertically integrated and restructured states. Mark Newton Lowry and Matt Makos of Pacific Energy Group Research and Jeff Deason of Berkeley Lab authored the report; Lisa Schwartz, Berkeley Lab, was project manager and technical editor.The report is aimed primarily at state utility regulators and stakeholders in the state regulatory process. The multiyear rate approach also provides ideas on how to streamline oversight of public power utilities and rural electric cooperatives for their governing boards.Two key provisions of multiyear rate plans strengthen cost containment incentives and streamline regulation: 1. Reducing frequency of rate cases, typically to every four or five years 2. Using an attrition relief mechanism to escalate rates or revenue between rate cases to address cost pressures such as inflation and growth in number of customers, independently of the utility’s own cost Better utility performance can be achieved under well-designed multiyear rate plans while achieving lower regulatory costs. Benefits can be shared between utilities and their customers. But plans can be complex and involve significant changes in the regulatory system. Designing plans that stimulate utility performance without undue risk and share benefits fairly can be challenging.This report discusses the rationale for multiyear

Prevalence and causes of work disability among working-age U.S. adults, 2011-2013, NHIS.

Science.gov (United States)

Theis, Kristina A; Roblin, Douglas W; Helmick, Charles G; Luo, Ruiyan

2018-01-01

Chronic conditions are among the major causes of work disability (WD), which is associated with lower employment, less economic activity, and greater dependence on social programs, while limiting access to the benefits of employment participation. We estimated the overall prevalence of WD among working-age (18-64 years) U.S. adults and the most common causes of WD overall and by sex. Next, we estimated the prevalence and most common causes of WD among adults with 12 common chronic conditions by sex and age. We hypothesized that musculoskeletal conditions would be among the most common causes of WD overall and for individuals with other diagnosed chronic conditions. Data were obtained from years 2011, 2012, and 2013 of the National Health Interview Survey. WD was defined by a "yes" response to one or both of: "Does a physical, mental, or emotional problem NOW keep you from working at a job or business?" and "Are you limited in the kind OR amount of work you can do because of a physical, mental or emotional problem?" Overall, 20.1 million adults (10.4% (95% CI = 10.1-10.8) of the working-age population) reported WD. The top three most commonly reported causes of WD were back/neck problems 30.3% (95% CI = 29.1-31.5), depression/anxiety/emotional problems 21.0% (19.9-22.0), and arthritis/rheumatism 18.6 (17.6-19.6). Musculoskeletal conditions were among the three most common causes of WD overall and by age- and sex-specific respondents across diagnosed chronic conditions. Quantifying the prevalence and causes of work disability by age and sex can help prioritize interventions. Published by Elsevier Inc.

ECOWindS Joint Action Plan

DEFF Research Database (Denmark)

2014-01-01

The Joint Action Plan (JAP) is a deliverable of the ECOWindS project Work Package 4 (WP4) “Joint Action Plan”. It presents a plan of action or a roadmap for research, development, and innovation (RDI) for the Offshore Wind Service (OWS) industry. The objective of the JAP is to be an international...

The nuclear industry's plan to achieve new nuclear power plant orders in the 1990's

International Nuclear Information System (INIS)

Bayne, P.

1993-01-01

Since the Arab Oil Embargo of 1973, there has been a direct relationship between the growth in the Gross Domestic Product and the growth in the use of electricity in the United States. That close relationship between economic growth and electricity will continue. If that is true, the United States Department of Energy says this country will need between 190,000 to 275,000 megawatts of new generating capacity in the next 20 years. Electricity is one of the cleanest and most efficient uses of energy. Of all the ways to generate electricity, nuclear power plants are the cleanest, producing no air pollution and no greenhouse gases. To help supply the needed increase in electricity generating capacity, the US nuclear power industry has developed a Strategic Plan for Building New Nuclear Power Plants. The plan identified fourteen issues which must be dealt with to create the conditions under which utilities could place orders for new nuclear plants by the mid-1990's. The plan was published in November of 1990 and significant progress has been made on most of the fourteen issues. The plan and progress made are reviewed in depth

Glove box adaptation, installation and commissioning of WD-XRF system for determination of PuO2 in MOX fuel samples

International Nuclear Information System (INIS)

Aher, Sachin; Pandey, Ashish; Khan, F.A.; Das, D.K.; Kumar, Surendra; Behere, P.G.; Mohd Afzal

2015-01-01

Glove Box facility forms the foremost important confinement system at nuclear fuel fabrication facility for handling of Plutonium based MOX fuels. Due to limited resources of Natural Uranium and maximum utilization of thorium, India has adopted 'Close Fuel Cycle Strategy' which involves use of Plutonium based fuels in Thermal and Fast reactors. Plutonium being radio toxic material with a higher biological half-life, Plutonium based fuel fabrication facility requires special techniques and confinement as a primary method for protection against spreading of powder contamination. Glove Box along with dynamic ventilation and HEPA Filters forms the preeminent facility for safe handling of plutonium based MOX fuels. Various equipment's, systems and instruments associated with MOX fuel production are need to be adapted inside the Glove Box with considerations of safety, ergonomics, accessibility for operations and maintenance, connections of various feed through like electrical connections, gas line supply etc. Quality Control plays the vital role in production of MOX fuels to ensure the finest quality of product to meet the defined specifications of MOX fuels. Presently AFFF is fabricating MOX fuel containing 21% and 28% PuO 2 along with DDUO 2 the first core of PFBR. Precise quantification of PuO 2 in MOX fuel pellets is necessary process control steps after batch preparation in Milling and Mixing operation. At AFFF, WD-XRF is one of the system used for determination of percentage of PuO 2 in MOX fuel batch. Glove Box adaptation of WD-XRF system along with 30 Tones Hydraulic press for sample preparation is being carried out in Type VI and Type IV Glove Boxes connected through transfer tunnel. Due to restrictions of space inside the Glove Box, a special mechanism is developed and installed for safe titling of WD-XRF system inside the Glove Box during the need of maintenance. These Glove Boxes are leak tested by various leak testing technique to meet the

Policy planning for nuclear power: An overview of the main issues and requirements

International Nuclear Information System (INIS)

1993-08-01

This special report, Policy Planning for Nuclear Power: An Overview of the Main Issues and Requirements, has been prepared in response to the express request of a number of IAEA Member States for a document to assist makers in developing countries on the introduction of nuclear power. The report contains information on the political, governmental, economic, financial and technical issues and requirements associated with planning and implementing a safe, economic and reliable nuclear power programme. It highlights the main areas in which policies must be developed and decisions taken, as well as the role and responsibilities of government, the plant owner and national industry. Also presented are the main criteria to assist policy planners in defining options and strategies which can achieve a balance among such objectives as cost effective and efficient electricity production, realistic and acceptable financing arrangements, national development requirements, safety and environmental protection. Further information and details on the technical and other issues presented in this report are given in the list of related IAEA publications and documents at the end of this report

Wilson’s Disease: Expect the Unexpected

Science.gov (United States)

Al Moussawi, Hassan; Haddad, Fady G.; Felix, Richard; Mulrooney, Stephen M

2018-01-01

A 64-year-old woman, presented with abdominal distention, jaundice and resting tremor, was found to have liver injury and abnormal liver enzymes. A computed tomography (CT) scan of the abdomen and pelvis showed abdominopelvic ascites and signs of liver cirrhosis. An extensive liver disease workup was performed and came back negative; therefore, a liver biopsy was obtained and showed evidence of cirrhosis with elevated liver copper consistent with Wilson’s disease (WD). We report a unique case of late-onset WD in which the ceruloplasmin level and 24-h urinary copper excretion were all normal. PMID:29644160

International Thermonuclear Experimental Reactor: Physics issues, capabilities and physics program plans

International Nuclear Information System (INIS)

Wesley, J.C.

1997-01-01

Present status and understanding of the principal plasma-performance determining physics issues that affect the physics design and operational capabilities of the International Thermonuclear Experimental Reactor (ITER) [ITER EDA Agreement and Protocol 2 (International Atomic Energy Agency, Vienna, 1994)] are presented. Emphasis is placed on the five major physics-basis issues emdash energy confinement, beta limit, density limit, impurity dilution and radiation loss, and the feasibility of obtaining partial-detached divertor operation emdash that directly affect projections of ITER fusion power and burn duration performance. A summary of these projections is presented and the effect of uncertainties in the physics-basis issues is examined. ITER capabilities for experimental flexibility and plasma-performance optimization are also described, and how these capabilities may enter into the ITER physics program plan is discussed. copyright 1997 American Institute of Physics

Nuclear weapons modernization: Plans, programs, and issues for Congress

Science.gov (United States)

Woolf, Amy F.

2017-11-01

The United States is currently recapitalizing each delivery system in its "nuclear triad" and refurbishing many of the warheads carried by those systems. The plans for these modernization programs have raised a number of questions, both within Congress and among analysts in the nuclear weapons and arms control communities, about the costs associated with the programs and the need to recapitalize each leg of the triad at the same time. This paper covers four distinct issues. It begins with a brief review of the planned modernization programs, then addresses questions about why the United States is pursuing all of these modernization programs at this time. It then reviews the debate about how much these modernization programs are likely to cost in the next decade and considers possible changes that might reduce the cost. It concludes with some comments about congressional views on the modernization programs and prospects for continuing congressional support in the coming years.

Population issues in economic planning: uses of demography in business.

Science.gov (United States)

Graham, R J

1984-01-01

Economists use demography in planning and forecasting business needs. As a bank, Westpac uses the information for its own internal business purposes and to assess general economic trends. Externally, the bank is expected by government and the public to have some authoritative views on the state of the economy. To form these views, it is necessary to understand a very wide array of statistical indicators, including demographic statistics. The main population issues of concern are: size, location, and changes in the population of Australia as a whole and by State; labor force (including projections); age profile of Australia and by State. The major source for this information is the Australian Bureau of Statistics. More detailed patterns often emerge, particularly for individual States, from papers prepared by others. This information is used by Westpac in 3 main planning areas and 2 broad assessment areas: planning -- location of bank branches, products/services offered, and marketing of products/services; and assessment -- economic outlook (labor force, housing needs, demand for funds) and specific industries. Recently, Westpac restructured its organization to cater to the changing needs of customers and the changing geographic patterns of population spread. The bank now has 4 major groups: retail financial services for personal and commercial markets; corporate and international; management services; and group planning (includes economic department). To offer products that fit the market, the bank needs to know the characteristics of the population by age, spending patterns, lifestyle preferences, and investment needs. Within Australia, a relatively new service offered by most financial institutions, which is directly related to population issues, is a counseling service for retirees. Westpac has a product called Club 55, which is a package of services designed for persons who have retired or are planning to retire. Another clearly perceived community need is for

Genome-wide identification, sequence characterization, and protein-protein interaction properties of DDB1 (damaged DNA binding protein-1)-binding WD40-repeat family members in Solanum lycopersicum.

Science.gov (United States)

Zhu, Yunye; Huang, Shengxiong; Miao, Min; Tang, Xiaofeng; Yue, Junyang; Wang, Wenjie; Liu, Yongsheng

2015-06-01

One hundred DDB1 (damaged DNA binding protein-1)-binding WD40-repeat domain (DWD) family genes were identified in the S. lycopersicum genome. The DWD genes encode proteins presumably functioning as the substrate recognition subunits of the cullin4-ring ubiquitin E3 ligase complex. These findings provide candidate genes and a research platform for further gene functionality and molecular breeding study. A subclass of DDB1 (damaged DNA binding protein-1)-binding WD40-repeat domain (DWD) family proteins has been demonstrated to function as the substrate recognition subunits of the cullin4-ring ubiquitin E3 ligase complex. However, little information is available about the cognate subfamily genes in tomato (S. lycopersicum). In this study, based on the recently released tomato genome sequences, 100 tomato genes encoding DWD proteins that potentially interact with DDB1 were identified and characterized, including analyses of the detailed annotations, chromosome locations and compositions of conserved amino acid domains. In addition, a phylogenetic tree, which comprises of three main groups, of the subfamily genes was constructed. The physical interaction between tomato DDB1 and 14 representative DWD proteins was determined by yeast two-hybrid and co-immunoprecipitation assays. The subcellular localization of these 14 representative DWD proteins was determined. Six of them were localized in both nucleus and cytoplasm, seven proteins exclusively in cytoplasm, and one protein either in nucleus and cytoplasm, or exclusively in cytoplasm. Comparative genomic analysis demonstrated that the expansion of these subfamily members in tomato predominantly resulted from two whole-genome triplication events in the evolution history.

Education issues in disaster medicine: summary and action plan.

Science.gov (United States)

Armour, S J; Bastone, P; Birnbaum, M; Garrett, C; Greenough, P G; Manni, C; Ninomiya, N; Renderos, J; Rottman, S; Sahni, P; Shih, C L; Siegel, D; Younggren, B

2001-01-01

Change must begin with education. Theme 8 explored issues that need attention in Disaster Medicine education. Details of the methods used are provided in the introductory paper. The chairs moderated all presentations and produced a summary that was presented to an assembly of all of the delegates. The chairs then presided over a workshop that resulted in the generation of a set of action plans that then were reported to the collective group of all delegates. Main points developed during the presentations and discussion included: (1) formal education, (2) standardized definitions, (3) integration, (4) evaluation of programs and interventions, (5) international cooperation, (6) identifying the psychosocial consequences of disaster, (7) meaningful research, and (8) hazard, impact, risk and vulnerability analysis. Three main components of the action plans were identified as evaluation, research, and education. The action plans recommended that: (1) education on disasters should be formalized, (2) evaluation of education and interventions must be improved, and (3) meaningful research should be promulgated and published for use at multiple levels and that applied research techniques be the subject of future conferences. The one unanimous conclusion was that we need more and better education on the disaster phenomenon, both in its impacts and in our response to them. Such education must be increasingly evidence-based.

Distributed generation - SHPP - Small hydroelectric power plants: technical and environmental issues; Geracao distribuida - PCH'S: aspectos tecnicos e ambientais

Energy Technology Data Exchange (ETDEWEB)

Andrade, Moacyr Trindade de Oliveira [Comissao de Servicos Publicos de Energia do Estado de Sao Paulo (CSPE), SP (Brazil)]. E-mail: mtandrade@sp.gov.br

2004-07-01

The Brazilian electrical system is presenting significant changes in its organizational structure in order to adapt to the new government's policies, market characteristics and the need for expansion of generation systems (supply), transmission and distribution (transport), and commercialization (demand) of energy. The previous structure propitiated the absolute control of the Union in the introduction of new plants, searching for a prioritization to their unit cost of energy, used as an 'Index of Merit' and expressed by U.S. $ / MWh, with planning costs increasing extent. This alternative did not address the environmental issues, referring only those technical aspects and costs of implementation. The socio-environmental issues were relegated to second plan. The significant interest of manufacturers prioritized the {sup b}ig construction{sup ,} as the simultaneous achievement of several big constructions enabling the consolidation of a constant flow of resources and sedimentary longevity of the situation. This paper aims to discuss and present the benefits of distributed generation electric power, with features to complement the offer, but with benefits for micro-regions in which they are deployed, based on technical, economic and socio environmental issues. (author)

Public issues associated with planning a large diameter pipeline in a multi-use urban corridor

Energy Technology Data Exchange (ETDEWEB)

Buszynski, M. [SENES Consultants Ltd., Richmond Hill, ON (Canada)

2004-07-01

The demand for natural gas in a downtown area of Toronto is expected to increase significantly due to the proposed construction of two new generation stations. However, there are few opportunities to locate the pipelines in large urban centers because of the lack of foresight by municipalities and others in preserving corridors for utilities. Enbridge Gas conducted a system planning study to determine the best methods for overcoming public issues that were encountered while planning the route for a NPS 36 inch diameter natural gas pipeline in this urban region. In Ontario, distribution pipelines are regulated by the Ontario Energy Board, whose environmental guidelines for the location, construction and operation of hydrocarbon pipelines require the identification of indirectly affected landowners and detailed analysis of public issues and how they can be resolved. Issues include noise, vibration, dust and traffic. Secondary use of the electric transmission rights-of-way resulted in the identification of several other issues, including aesthetics of the right-of-way and loss of privacy for adjacent residential properties. It was determined that the optimal solution was to parallel a section of existing NPS 30 pipeline running in a north-south right-of-way located east of the Don Valley Parkway. The techniques used to address public issues identified 180 directly affected and 3,200 indirectly affected landowners. The Enbridge study revealed that it is possible to plan a right-of-way through an urban corridor in a manner that is compatible with existing development and that satisfies the general public. 6 figs.

International Population Assistance and Family Planning Programs: Issues for Congress

National Research Council Canada - National Science Library

Blanchfield, Luisa

2008-01-01

...." The Mexico City policy denies U.S. funds to foreign nongovernmental organizations (NGOs) that perform or promote abortion as a method of family planning -- even if the activities are undertaken with non-U.S. funds...

Technical planning activity: Final report

Energy Technology Data Exchange (ETDEWEB)

1987-01-01

In April 1985, the US Department of Energy's (DOE's) Office of Fusion Energy commissioned the Technical Planning Activity (TPA). The purpose of this activity was to develop a technical planning methodology and prepare technical plans in support of the strategic and policy framework of the Magnetic Fusion Program Plan issued by DOE in February 1985. Although this report represents the views of only the US magnetic fusion community, it is international in scope in the sense that the technical plans contained herein describe the full scope of the tasks that are prerequisites for the commercialization of fusion energy. The TPA has developed a well-structured methodology that includes detailed definitions of technical issues, definitions of program areas and elements, statements of research and development objectives, identification of key decision points and milestones, and descriptions of facility requirements.

Successful Splenectomy for Hypersplenism in Wilson’s Disease: A Single Center Experience from China

Science.gov (United States)

Chen, Huai-Zhen; Wu, Yun-Hu; Fang, Xiang; Zhang, Jing; Wang, Zhen; Han, Yong-Sheng; Wang, Yu

2015-01-01

Splenomegaly and pancytopenia are common in Wilson’s disease (WD) and splenectomy is one of the conventional treatments for splenomegaly and the associated pancytopenia. However, splenectomy remained controversial for hypersplenism in WD as it was reported that splenectomy leaded to serious emotional and neurological deterioration in WD patients with hypersplenism. In the current study, we present our experiences in 70 WD patients with hypersplenism who had undergone splenectomy, outlining the safety and efficacy of splenectomy in WD. The clinical database of 70 WD patients with hypersplenism who had undergone splenectomy in our hospital between 2009 and 2013 were reviewed and followed-up regularly. Before splenectomy, all the patients accepted a short period of anti-copper treatment with intravenous sodium 2, 3-dimercapto-1-propane sulfonate (DMPS). All the patients demonstrated a marked improvement in platelet and leucocyte counts after splenectomy. No severe postoperative complication was observed. In particular, none of the 37 patients with mixed neurologic and hepatic presentations experienced neurological deterioration after splenectomy, and none of the patients with only hepatic presentations newly developed neurological symptoms. During the one year follow-up period, no patient presented hepatic failure or hepatic encephalopathy, no hepatic patient newly developed neurological presentations, and only 3 patients with mixed neurologic and hepatic presentations suffered neurological deterioration and these 3 patients had poor compliance of anti-copper treatment. Quantative analysis of the neurological symptoms in the 37 patients using the Unified Wilson’s Disease Rating Scale (UWDRS) showed that the neurological symptoms were not changed in a short-term of one week after splenectomy but significantly improved in a long-term of one year after splenectomy. Additionally, compared to that before splenectomy, the esophageal gastric varices in most patients

Planning Electric Transmission Lines: A Review of Recent Regional Transmission Plans

Energy Technology Data Exchange (ETDEWEB)

Eto, Joseph H. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

2017-04-13

The first Quadrennial Energy Review (QER) recommends that the U.S. Department of Energy (DOE) conduct a national review of transmission plans and assess the barriers and incentives to their implementation. DOE tasked Lawrence Berkeley National Laboratory (LBNL) to prepare two reports to support the agency’s response to this recommendation. This report reviews regional transmission plans and regional transmission planning processes that have been directed by Federal Energy Regulatory Commission (FERC) Order Nos. 890 and 1000. We focus on the most recent regional transmission plans (those issued in 2015 and through approximately mid-year 2016) and current regional transmission planning processes. A companion report focuses on non-plan-related factors that affect transmission projects.

The Jasmonate-ZIM-domain proteins interact with the WD-Repeat/bHLH/MYB complexes to regulate Jasmonate-mediated anthocyanin accumulation and trichome initiation in Arabidopsis thaliana.

Science.gov (United States)

Qi, Tiancong; Song, Susheng; Ren, Qingcuo; Wu, Dewei; Huang, Huang; Chen, Yan; Fan, Meng; Peng, Wen; Ren, Chunmei; Xie, Daoxin

2011-05-01

Jasmonates (JAs) mediate plant responses to insect attack, wounding, pathogen infection, stress, and UV damage and regulate plant fertility, anthocyanin accumulation, trichome formation, and many other plant developmental processes. Arabidopsis thaliana Jasmonate ZIM-domain (JAZ) proteins, substrates of the CORONATINE INSENSITIVE1 (COI1)-based SCF(COI1) complex, negatively regulate these plant responses. Little is known about the molecular mechanism for JA regulation of anthocyanin accumulation and trichome initiation. In this study, we revealed that JAZ proteins interact with bHLH (Transparent Testa8, Glabra3 [GL3], and Enhancer of Glabra3 [EGL3]) and R2R3 MYB transcription factors (MYB75 and Glabra1), essential components of WD-repeat/bHLH/MYB transcriptional complexes, to repress JA-regulated anthocyanin accumulation and trichome initiation. Genetic and physiological evidence showed that JA regulates WD-repeat/bHLH/MYB complex-mediated anthocyanin accumulation and trichome initiation in a COI1-dependent manner. Overexpression of the MYB transcription factor MYB75 and bHLH factors (GL3 and EGL3) restored anthocyanin accumulation and trichome initiation in the coi1 mutant, respectively. We speculate that the JA-induced degradation of JAZ proteins abolishes the interactions of JAZ proteins with bHLH and MYB factors, allowing the transcriptional function of WD-repeat/bHLH/MYB complexes, which subsequently activate respective downstream signal cascades to modulate anthocyanin accumulation and trichome initiation.

Ukraine: Current Issues and U.S. Policy

Science.gov (United States)

2014-09-04

as Putin’s attempt to test how far he can go in destabilizing Ukraine while avoiding the imposition of additional sanctions by the EU and United...cooperative threat reduction and other nonproliferation activities with Russia. Figure 1. Ukraine Ukraine: Current Issues and U.S. Policy

Updated science issues and observation plans of BepiColombo Mercury Magnetosphere Orbiter (MMO)

Science.gov (United States)

Murakami, G.; Fujimoto, M.; Hayakawa, H.

2017-12-01

After the successful observation by the first Mercury orbiter MESSENGER ended in 2015, Mercury becomes one of the most curious planets to investigate. MESSENGER raised new science issues, such as the northward offset of planetary dipole magnetic filed, the highly dynamic magnetosphere, and the year-to-year constant exosphere. These outstanding discoveries still remain as open issues due to some limitations of instruments onboard MESSENGER and its extended elliptical orbit with apherm in southern hemisphere. The next Mercury exploration project BepiColombo will address these open issues. BepiColombo is an ESA-JAXA joint mission to Mercury with the aim to understand the process of planetary formation and evolution as well as to understand Mercury's extreme environment in the solar system. Two spacecraft, i.e. the Mercury Planetary Orbiter (MPO) and the Mercury Magnetospheric Orbiter (MMO), will be launched in October 2018 by an Ariane-5 launch vehicle and arrive at Mercury in December 2025. The mechanical test in a complete stack configuration has been performed in the ESA test center and successfully finished. MMO is mainly designed for plasma observations and is expected to extract essential elements of space plasma physics that become visible in the Hermean environment. MMO has large constraints on science operations, such as thermal issue and limited telemetry rate. Due to the thermal issue each science instrument cannot always be turned on. In addition, due to the low telemetry rate in average, only a part ( 20-30%) of science mission data with high resolution can be downlinked. Therefore, in order to maximize the scientific results and outcomes to be achieved by MMO, we are now working to optimize the science observation and downlink plans in detail. Here we present the updated science goals for MMO based on the latest MESSENGER results and the current observation plans how to approach these science issues.

U.S.-China Counterterrorism Cooperation: Issues for U.S. Policy

National Research Council Canada - National Science Library

Kan, Shirley A

2008-01-01

... (Operation Enduring Freedom). Longer-term issues have concerned whether counterterrorism has strategically transformed bilateral relations and whether China's support has been valuable and not obtained at the expense of other U.S. interests...

Plan well, plan often

Science.gov (United States)

Bill Block

2013-01-01

This issue includes an invited paper by Courtney Schultz and her colleagues commenting on the application of the newly adopted U.S. Forest Service Planning Rule (hereafter, the rule) for wildlife. The rule is basically implementing language to interpret the spirit and intent of the National Forest Management Act (NFMA) of 1976. Laws such as NFMA require additional...

41 CFR 102-76.20 - What issues must Federal agencies consider in providing site planning and landscape design services?

Science.gov (United States)

2010-07-01

... agencies consider in providing site planning and landscape design services? 102-76.20 Section 102-76.20... What issues must Federal agencies consider in providing site planning and landscape design services? In providing site planning and design services, Federal agencies must— (a) Make the site planning and landscape...

Extraction of resins from WD-22 tank in Jose Cabrera Nuclear Power Plant

International Nuclear Information System (INIS)

Benavides, E.

1997-01-01

The Spent Resin Tank (WD-22) is located in the Auxiliary Building of Jose Cabrera Nuclear Plant (PWR 150 Mwe). This tank has a nominal capacity of 4 m 3 and is almost full of spent resins that has been stored from the late sixties to early eighties. As the lines are completely plugged with resins and due to the difficulties in the pipe lay-out, it has not been possible to transfer the resins to the cementation plant since that date. The plant decided, by an open bid quotation, to select the most suitable process to transfer the resins to the cementation plant avoiding the high doses existing in the tank cubicle and in a reasonable time schedule. The solution given in this paper contemplates that sometimes there is an imaginative answer to a problem that seems to be difficult to solve. (authors)

Plan de empresa DROP S.A.S. artículos y accesorios para mascotas

OpenAIRE

2012-01-01

Este trabajo es un plan de empresa que determina la viabilidad del proyecto DROP S.A.S, que tiene como finalidad la producción y comercialización de artículos para mascotas. Para lograr este fin, se ha realizado el plan de mercadeo, plan de producción, plan de organización y plan financiero, al hacer un estudio detallado de cada uno de estos módulos Inicialmente se elaboró el plan de mercadeo, en el que se hizo un análisis de las fuerzas del entorno, dentro del cual, se encuentra el estud...

[Materiality Analysis of Health Plans Based on Stakeholder Engagement and the Issues Included at ISO 26000:2010].

Science.gov (United States)

Moyano Santiago, Miguel Angel; Rivera Lirio, Juana María

2017-01-18

Health plans of the Spanish autonomous communities can incorporate sustainable development criteria in its development. There have been no analysis or proposals about development and indicators. The goal is to add a contribution to help build better health plans aimed at sustainable development and help to manage economic, social and environmental impacts of health systems criteria. We used a variation of the RAND/UCLA or modified Delphi technique method. The process consisted of a bibliographical and context matters and issues related to health and social responsibility analysis based on ISO 26000: 2010. A survey by deliberately to a selection of 70 expert members of the identified stakeholders was carried out and a discussion group was held to determine the consensus on the issues addressed in the survey sample. The research was conducted in 2015. From the literature review 33 health issues included in ISO 26000:2010 were obtained. 7 survey proved relevant high consensus, 8 relevance and average consensus and 18 with less relevance and high level of dissent. The expert group excluded 4 of the 18 subjects with less consensus. 29 issues included 33 at work, divided into 7 subjects contained in the guide ISO 26000 of social responsibility, were relevant stakeholders regarding possible inclusion in health plans. Considering the direct relationship published by ISO (International Organization for Standardization) among the issues ISO 26000 and the economic, social and environmental indicators in GRI (Global Reporting Initiative) in its G4 version, a panel with monitoring indicators related to relevant issues were elaborated.

Transportation Institutional Plan

Energy Technology Data Exchange (ETDEWEB)

1986-08-01

This Institutional Plan is divided into three chapters. Chapter 1 provides background information, discusses the purposes of the Plan and the policy guidance for establishing the transportation system, and describes the projected system and the plans for its integrated development. Chapter 2 discusses the major participants who must interact to build the system. Chapter 3 suggests mechanisms for interaction that will foster wide participation in program planning and implementation and provides a framework for managing and resolving the issues related to development and operation of the transportation system. A list of acronyms and a glossary are included for the reader's convenience. Also included in this Plan are four appendices. Of particular importance is Appendix A, which includes detailed discussion of specific transportation issues. Appendices B, C, and D provide supporting material to assist the reader in understanding the roles of the involved institutions.

FY 1996 annual work plan

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-09-30

In April 1994, the Department of Energy (DOE) Strategic Plan was issued. This Plan presents the Department`s strategic outlook in response to a changing world. It discusses the Department`s unique capabilities; its mission, vision, and core values; and key customer and stakeholder considerations. The DOE Strategic Plan lists business strategies and critical success factors which are intended to aid the Department in accomplishing its mission and reaching its vision of itself in the future. The Office of Inspector General (OIG) has an important role in carrying out the goals and objectives of the Secretary`s Strategic Plan. The ultimate goal of the OIG is to facilitate positive change by assisting its customers, responsible Government officials, in taking actions to improve programs and operations. The Inspector General annually issues his own Strategic Plan that contains program guidance for the next fiscal year. As part of its responsibility in carrying out the OIG mission, the Office of the Deputy Inspector General for Audit Services (Office of Audit Services) publishes an Annual Work Plan that sets forth audits that are planned for the next fiscal year. Selection of these audits is based on the overall budget of the Department, analyses of trends in Departmental operations, guidance contained in the agency`s strategic plans, statutory requirements, and the expressed needs and audit suggestions of Departmental program managers and OIG managers and staff. This work plan includes audits that are carried over from FY 1995 and audits scheduled to start during FY 1996. Audits included in the plan will be performed by OIG staff.

Unresolved safety issues summary: aqua book

International Nuclear Information System (INIS)

1983-06-01

The unresolved safety issues summary is designed to provide the management of the nuclear regulatory commission with a quarterly overview of the progress and plans for completion of generic tasks addressing unresolved safety issues reported to congress pursuant to section 210 of the Energy Reorganization Act of 1974 as amended. The schedules in this book include a milestone at the end of each action plan which represents the initiation of the implementation process both with respect to incorporation of the technical resolution in the NRC official guidance or requirements and also the application of changes to individual operating plants. The schedule for implementation will not normally be included in the task action plan(s) for the resolution of a USI since the nature and extent of the activities necessary to accomplish the implementation cannot normally be reasonably determined prior to the determination of a technical resolution. The progress and status for implementation of unresolved safety issues for which a technical resolution has been completed are reported specifically in a separate table provided in this summary

Plan de marketing: Dougall’s

OpenAIRE

Cambero Yllera, Jaime

2016-01-01

RESUMEN: El presente Trabajo Fin de Grado supone un acercamiento al sector cervecero en España, y su objetivo fundamental es elaborar un Plan de Marketing para una empresa de cerveza en Liérganes, Cantabria; cerveza Dougall’s. El Plan de Marketing de la empresa estará enfocado a la creación de un nuevo producto, una cerveza de trigo. Para ello partiremos de cero, mostrando todos los pasos necesarios que conlleva el lanzamiento del producto, desde el comienzo de su elaboración en fabrica hasta...

International Population Assistance and Family Planning Programs: Issues for Congress

National Research Council Canada - National Science Library

Nowels, Larry; Veillette, Connie

2006-01-01

.... international family planning programs. In 1984, controversy arose over U.S. population aid policy when the Reagan Administration introduced restrictions, which became known as the "Mexico City policy...

International Population Assistance and Family Planning Programs: Issues for Congress

National Research Council Canada - National Science Library

Blanchfield, Luisa

2008-01-01

.... international family planning programs. In 1984, controversy arose over U.S. population aid policy when the Reagan Administration introduced restrictions, which became known as the "Mexico City policy...

The analysis of strategic planning in transport

OpenAIRE

Išoraitė, Margarita

2006-01-01

Strategic planning is a process whish brings to life the mission and vision of an enterprise. The article analyses the following issues: 1. Concepts of strategy. 2. Components of strategic planning. 3. The basis of strategic planning. 4. Formal strategic planning. 5. Tools used in strategy development. 6. Problems of strategic planning. Strateginis planavimas yra procesas, kurio metu įgyvendinami įmonės tikslai. Šiame straipsnyje nagrinėjama: strategijos sąvoka; strateginio planavimo kompo...

International Population Assistance and Family Planning Programs: Issues for Congress

National Research Council Canada - National Science Library

Nowels, Larry; Veillette, Connie

2006-01-01

Since 1965, U.S. policy has supported international population planning based on principles of volunteerism and informed choice that gives participants access to information on all methods of birth control...

Planning issues for IMRT

International Nuclear Information System (INIS)

Hoban, P.; Schneider, M.; Smee, R.

2001-01-01

Full text: Despite the 'inverse planning' stage of an intensity modulated radiotherapy (IMRT) treatment there remains a large number of variables that can, and must, be set manually. These variables can significantly affect the quality of the dose distribution arrived at by the optimisation. Clinical IMRT planning with the Radionics XPlan system for micro-multileaf collimator (MMLC) delivery has allowed for important lessons to be learned regarding the best beam and organ configurations prior to optimisation of beamlet weights. Important user-definable variables are beam directions, organ parameters (dose goals/penalties), and the margin (if any) around the planning target volume (PTV) used to aid coverage. Conventional stereotactic radiotherapy (SRT) treatments typically involve non-coplanar beams since there is often an advantage in terms of cranial organ at risk (OAR) sparing. IMRT can also benefit from such a configuration. The balance between target coverage and OAR sparing is largely controlled by user-defined goal doses and penalties. Once optimisation has been performed, intensity maps can be discretised into a selected number of levels. Less levels means less field segments and thus a shorter treatment time. Although IMRT beams attempt to spare structures which are in the 'beam's eye view' (BEV) of the target volume, sparing is greater if beams which minimise the involvement of OARs in their view are used. It has been found that the use of a margin is an effective way to ensure adequate PTV coverage. Alternatively the PTV penalties can be made larger. The best result is often obtained by the use of a 3-4 mm margin, whose penalty for underdosage is somewhat less than that for the PTV. Discretising the intensity maps to 4 or 5 levels is typically a good balance between shortening treatment time and not overly degrading the dose distribution. Beam configuration is still an important step in IMRT planning, even though optimisation of intensity maps is

International Population Assistance and Family Planning Programs: Issues for Congress

National Research Council Canada - National Science Library

Blanchfield, Luisa

2008-01-01

Since 1965, the U.S. Government has supported international population planning based on principles of volunteerism and informed choice that gives participants access to information on all methods of birth control...

Do U.S. family planning clinics encourage parent-child communication? Findings from an exploratory survey.

Science.gov (United States)

Jones, Rachel K

2006-09-01

Clinics that receive Title X funding have a mandate to encourage parent-child communication for minors seeking family planning services. Little is known about the programs and practices that clinics have adopted to achieve this goal, or whether clinics not receiving Title X funds encourage family participation. As part of a larger project examining parental engagement among adolescents using family planning clinics, 81 clinics that served 200 or more adolescent contraceptive clients in 2001 completed a questionnaire containing closed- and open-ended items. Topic areas included clinic counseling and policies regarding clients younger than 18, activities to improve parent-child communication and community relations. Frequency distributions were calculated for the prevalence of activities, and cross-tabulations were used to compare prevalence by clinic characteristics. Every clinic engaged in at least one activity to promote parent-child communication, and nine in 10 offered multiple activities. Most of the clinics used counseling sessions to talk to adolescent clients about the importance of discussing sexual health issues with parents (73-94%, depending on the reason for the visit). More than eight in 10 clinics (84%) distributed pamphlets on how to talk about these issues. A substantial minority (43%) offered or referred interested individuals to educational programs designed to improve communication. Some of these exploratory findings reflect the prevalence of activities among all U.S. family planning clinics that serve adolescent clients. Evaluation and expansion of clinic efforts to promote voluntary communication about sexual health issues between parents and children could help encourage family participation.

Choosing Pre-conception Planning for Women/Families: Counselling and Informed Consent (Part 2) - Pre-conception Reproductive Planning, Lifestyle, Immunization, and Psychosocial Issues.

Science.gov (United States)

Wilson, R Douglas

2017-12-06

To inform reproductive and other health care providers about pre-conception evaluation, including considerations for reproductive planning, lifestyle modification, immunization status and attitudes, and psychosocial issues. This counselling information can be used for patient education and planning and possible pre-conception and/or prenatal testing. This information may allow for improved risk assessment when pre-conception counselling for individual patients and their families is used. CONSIDERATIONS FOR PRE-CONCEPTION CARE (PART 2) REGARDING PRE-CONCEPTION REPRODUCTIVE PLANNING, LIFESTYLE, IMMUNIZATIONS, AND PSYCHOSOCIAL ISSUES: CONSIDERATION FOR CARE STATEMENTS: For this review article, the Consideration for Care Statements use the Grading of Recommendations, Assessment, Development and Evaluations strength and quality principles because they are comparable for the clinician and the patient/public user. For example, "Strong" for clinicians is defined as "the recommendation would apply to most individuals. Formal discussion aids are not likely to be needed to help individuals make decisions consistent with their values and preferences." For patients/the public, "Strong" is defined as, "we believe most people in this situation would want the recommended course of actions and only a small number would not." Quality of evidence (High, Moderate, Low) is based on the confidence that the true effect lies close to that of the estimate of the effect. In addition, the Canadian Task Force on Preventive Health Care key to evidence statements and grading of recommendations are included. PubMed, Medline, and the Cochrane Database were searched until May 2017, using appropriate key words (i.e., preconception, reproductive planning, lifestyle modification, immunization risks and benefits, psychosocial pregnancy factors/issues). Grey (unpublished) literature was identified through searching websites of health technology assessment and health technology assessment

Integrating population variation and protein structural analysis to improve clinical interpretation of missense variation: application to the WD40 domain.

Science.gov (United States)

Laskowski, Roman A; Tyagi, Nidhi; Johnson, Diana; Joss, Shelagh; Kinning, Esther; McWilliam, Catherine; Splitt, Miranda; Thornton, Janet M; Firth, Helen V; Wright, Caroline F

2016-03-01

We present a generic, multidisciplinary approach for improving our understanding of novel missense variants in recently discovered disease genes exhibiting genetic heterogeneity, by combining clinical and population genetics with protein structural analysis. Using six new de novo missense diagnoses in TBL1XR1 from the Deciphering Developmental Disorders study, together with population variation data, we show that the β-propeller structure of the ubiquitous WD40 domain provides a convincing way to discriminate between pathogenic and benign variation. Children with likely pathogenic mutations in this gene have severely delayed language development, often accompanied by intellectual disability, autism, dysmorphology and gastrointestinal problems. Amino acids affected by likely pathogenic missense mutations are either crucial for the stability of the fold, forming part of a highly conserved symmetrically repeating hydrogen-bonded tetrad, or located at the top face of the β-propeller, where 'hotspot' residues affect the binding of β-catenin to the TBLR1 protein. In contrast, those altered by population variation are significantly less likely to be spatially clustered towards the top face or to be at buried or highly conserved residues. This result is useful not only for interpreting benign and pathogenic missense variants in this gene, but also in other WD40 domains, many of which are associated with disease. © The Author 2016. Published by Oxford University Press.

U.S.-Mexico Economic Relations: Trends, Issues, and Implications

Science.gov (United States)

2012-01-25

Time,” Economia , Fall 2003. 49 Esquivel, Gerardo, and José Antonio Rodríguez-López, “Technology, trade, and wage inequality in Mexico before and after...CRS Report for Congress Prepared for Members and Committees of Congress U.S.- Mexico Economic Relations: Trends, Issues, and Implications...25 JAN 2012 2. REPORT TYPE 3. DATES COVERED 00-00-2012 to 00-00-2012 4. TITLE AND SUBTITLE U.S.- Mexico Economic Relations: Trends, Issues, and

The vital issues process: Strategic planning for a changing world

Energy Technology Data Exchange (ETDEWEB)

Engi, D.; Glicken, J.

1995-05-01

The Vital Issues process (VIp) is a strategic planning tool initially developed by Sandia National Laboratories (SNL) for the Office of Foreign Intelligence (OFI)* of the US Department of Energy (DOE). It was further developed and refined through its application to a variety of strategic purposes for a range of public and semipublic organizations. The VIp provides a structured mechanism for assisting organizations in accomplishing specified objectives by identifying and prioritizing a portfolio of strategic issues, programmatic areas, or responses to a specified problem. It employs day-long panel meetings in a specified format to elicit a broad range of perspectives on a particular issue in a nonconfrontational manner and to facilitate the interaction and synthesis of diverse viewpoints on a specific topic. The VIp is unique in its incorporation of two primary approaches in each panel session: a qualitative or transactional segment, which entails the synthesis of the alternatives through negotiations or discussion, and a quantitative or net benefit maximization segment, an analytical approach, which involves prioritization of the alternatives using pairwise comparisons. This combination of facilitated group discussion and quantitative ranking provides input to strategic management decisions in the form of stakeholder-defined and -prioritized items as well as information on potential barriers to the implementation of policies and programs. This is the final volume in the series Identifying Vital Issues: New Intelligence Strategies for a New World, a three-volume set that gives an accounting of the VIp as implemented for OFI. This volume provides an in-depth description of the methodology used in the VIp.

American’s Energy Future: An Analysis of the Proposed Energy Policy Plans in Presidential Election

Directory of Open Access Journals (Sweden)

Ming-Hsun Cheng

2016-11-01

Full Text Available As the leader of the largest economy, President of the United States has substantive influence on addressing climate change problems. However, a presidential election is often dominated by issues other than energy problems. This paper focuses on the 2016 presidential election, and examines the energy plans proposed by the leading Democrat and Republican candidates. Our data from the Iowa caucus survey in January 2016 suggests that voters were more concerned about terrorism and economic issues than environmental issues. We then compare the Democratic and Republican candidate’s view of America’s energy future, and evaluate their proposed renewable energy targets. We find that the view on renewable energy is polarized between Democratic and Republican candidates, while candidates from both parties agree on the need for energy efficiency. Results from our ordinal least squares regression models suggests that Democratic candidates have moderate to ambitious goals for developing solar and other renewables. The Republican candidates favor fossil fuels and they choose not to provide any specific target for developing renewable energy. In addition, this trend of party polarization has grown more significant when compared with the past three presidential elections. Our observation suggests that energy policies need to be discussed more often regarding the diversification and decarbonization of the nation’s energy system.

Status report : British Columbia`s economic plan

Energy Technology Data Exchange (ETDEWEB)

NONE

1999-01-01

A sector-by-sector update of actions taken under British Columbia`s three-year economic plan is outlined and the progress to date reviewed. The three year plan includes the support for industry growth in partnership with the private sector, making Vancouver a major international conference destination, and developing Vancouver International Airport into a major gateway to the Pacific. The plan also includes the promotion of adventure tourism in major international markets, and promoting aboriginal tourism and culture. The government also plans to stimulate the economy by providing $973 million in tax reductions for BC families and business. 1 tab.

Federal Employees Health Benefits Program: Enrollment Options Following the Termination of a Plan or Plan Option. Final rule.

Science.gov (United States)

2015-10-28

The U.S. Office of Personnel Management (OPM) is issuing a final rule to amend the Federal Employees Health Benefits (FEHB) Program regulations regarding enrollment options following the termination of a plan or plan option.

Rationale and operational plan for a U.S. high-altitude magnetic survey

Science.gov (United States)

Hildenbrand, Thomas G.; Acuna, Mario; Bracken, Robert E.; Hardwick, Doug; Hinze, William J.; Keller, Gordon R.; Phillips, Jeff; Roest, Walter

2002-01-01

On August 8, 2002, twenty-one scientists from the federal, private and academic sectors met at a workshop in Denver, Co., to discuss the feasibility of collecting magnetic anomaly data on a Canberra aircraft (Figure 1). The need for this 1-day workshop arose because of an exciting and cost-effective opportunity to collect invaluable magnetic anomaly data during a Canberra mission over the U.S. in 2003 and 2004. High Altitude Mapping Missions (HAMM) is currently planning a mission to collect Interferometric Synthetic Aperture Radar (IFSAR) imagery at an altitude of about 15 km and with a flight-line spacing of about 18 km over the conterminous U.S. and Alaska. The additional collection of total and vector magnetic field data would represent a secondary mission objective (i.e., a "piggy-back" magnetometer system). Because HAMM would fund the main flight costs of the mission, the geomagnetic community would obtain invaluable magnetic data at a nominal cost. These unique data would provide new insights on fundamental tectonic and thermal processes and give a new view of the structural and lithologic framework of the crust and possibly the upper mantle. This document highlights: (1) the reasons to conduct this national survey and (2) a preliminary operational plan to collect high-altitude magnetic data of a desired quality and for the expected resources. Although some operational plan issues remain to be resolved, the important conclusions of the workshop are that the Canberra is a very suitable platform to measure the magnetic field and that the planned mission will result in quality high-altitude magnetic data to greatly expand the utility of our national magnetic database.

Workshop on Regulatory Review and Safety Assessment Issues in Repository Licensing

Energy Technology Data Exchange (ETDEWEB)

Wilmot, Roger D. (Galson Sciences Limited (United Kingdom))

2011-02-15

The workshop described here was organised to address more general issues regarding regulatory review of SKB's safety assessment and overall review strategy. The objectives of the workshop were: - to learn from other programmes' experiences on planning and review of a license application for a nuclear waste repository, - to offer newly employed SSM staff an opportunity to learn more about selected safety assessment issues, and - to identify and document recommendations and ideas for SSM's further planning of the licensing review

Japan-U.S. Relations: Issues for Congress

Science.gov (United States)

2013-02-15

China called for a boycott on Japanese goods and defaced Japanese retail stores. Japanese auto manufacturers experienced sharp declines in sales in...TPP is now an agreement under negotiation among the original four countries plus the United States, Australia, Canada, Mexico, Peru, Malaysia , and...Inside U.S. Trade, April 27, 2012. 44 World Trade Online , April 5, 2012. Japan-U.S. Relations: Issues for Congress Congressional Research Service 25

The Jasmonate-ZIM-Domain Proteins Interact with the WD-Repeat/bHLH/MYB Complexes to Regulate Jasmonate-Mediated Anthocyanin Accumulation and Trichome Initiation in Arabidopsis thaliana[C][W

Science.gov (United States)

Qi, Tiancong; Song, Susheng; Ren, Qingcuo; Wu, Dewei; Huang, Huang; Chen, Yan; Fan, Meng; Peng, Wen; Ren, Chunmei; Xie, Daoxin

2011-01-01

Jasmonates (JAs) mediate plant responses to insect attack, wounding, pathogen infection, stress, and UV damage and regulate plant fertility, anthocyanin accumulation, trichome formation, and many other plant developmental processes. Arabidopsis thaliana Jasmonate ZIM-domain (JAZ) proteins, substrates of the CORONATINE INSENSITIVE1 (COI1)–based SCFCOI1 complex, negatively regulate these plant responses. Little is known about the molecular mechanism for JA regulation of anthocyanin accumulation and trichome initiation. In this study, we revealed that JAZ proteins interact with bHLH (Transparent Testa8, Glabra3 [GL3], and Enhancer of Glabra3 [EGL3]) and R2R3 MYB transcription factors (MYB75 and Glabra1), essential components of WD-repeat/bHLH/MYB transcriptional complexes, to repress JA-regulated anthocyanin accumulation and trichome initiation. Genetic and physiological evidence showed that JA regulates WD-repeat/bHLH/MYB complex-mediated anthocyanin accumulation and trichome initiation in a COI1-dependent manner. Overexpression of the MYB transcription factor MYB75 and bHLH factors (GL3 and EGL3) restored anthocyanin accumulation and trichome initiation in the coi1 mutant, respectively. We speculate that the JA-induced degradation of JAZ proteins abolishes the interactions of JAZ proteins with bHLH and MYB factors, allowing the transcriptional function of WD-repeat/bHLH/MYB complexes, which subsequently activate respective downstream signal cascades to modulate anthocyanin accumulation and trichome initiation. PMID:21551388

Institutional Plan FY 2003 - 2007

Energy Technology Data Exchange (ETDEWEB)

Chartock, Michael; Hansen, Todd

2003-01-27

The Fiscal Year (FY) 2003-2007 Institutional Plan describes the strategic directions and key issues that Lawrence Berkeley National Laboratory management must address with the Department of Energy (DOE) in charting its future as a multiprogram national laboratory. The Plan provides an overview of the Laboratory's mission, strategic plan, initiatives, and the resources required to fulfill its role in support of national needs in fundamental science and technology, energy resources, and environmental quality. The Plan facilitates the Department of Energy's ongoing efforts to strengthen the Integrated Laboratory System. Preparation and review of the Institutional Plan is one element of the Department of Energy's strategic management planning activities, implemented through an annual planning process. The Plan supports the President's Management Agenda and the Government Performance and Results Act of 1993. The Plan complements the current performance-based contract between the Department of Energy and the Regents of the University of California, and summarizes Best Management Practices for a potential future results-based contract as a basis for achieving DOE goals and the Laboratory's scientific and operations objectives. It identifies technical and administrative directions in the context of national energy policy and research needs and the Department of Energy's program planning initiatives. Preparation of the Plan is coordinated by the Planning and Strategic Development Office from information contributed by Berkeley Lab's scientific and support divisions and DOE comments on prior years' plans. The Laboratory Mission section identifies the specific strengths of Berkeley Lab that contribute to the mission in general and the Integrated Laboratory System in particular. The Laboratory Strategic Plan section identifies the existing activities in support of DOE Office of Science and other sponsors; support for DOE goals; and the

Science and technology planning in LDCs: major policy issues

Energy Technology Data Exchange (ETDEWEB)

Wionczek, M S

1979-05-01

Science in the less-developed countries (LDCs) should be underplanned rather than overplanned. Furthermore, the planning should be directed to the outer fringes of the scientific endeavor and to its infrastructure and not to the substance of scientific research itself. Planning of applied research and technological development in the LDC is another story. It cannot be done without entering into the substantive problems of applied research and technological development. Attempts to set the broad overall national targets for science and technology (S and T) expenditures -in terms of the proportion of the (GNP) or the per capita income- which do not consider the science and technology system's financial and human resources absorption capacity, are useless. 8 references.

S-phenylpiracetam, a selective DAT inhibitor, reduces body weight gain without influencing locomotor activity.

Science.gov (United States)

Zvejniece, Liga; Svalbe, Baiba; Vavers, Edijs; Makrecka-Kuka, Marina; Makarova, Elina; Liepins, Vilnis; Kalvinsh, Ivars; Liepinsh, Edgars; Dambrova, Maija

2017-09-01

S-phenylpiracetam is an optical isomer of phenotropil, which is a clinically used nootropic drug that improves physical condition and cognition. Recently, it was shown that S-phenylpiracetam is a selective dopamine transporter (DAT) inhibitor that does not influence norepinephrine (NE) or serotonin (5-HT) receptors. The aim of the present study was to study the effects of S-phenylpiracetam treatment on body weight gain, blood glucose and leptin levels, and locomotor activity. Western diet (WD)-fed mice and obese Zucker rats were treated daily with peroral administration of S-phenylpiracetam for 8 and 12weeks, respectively. Weight gain and plasma metabolites reflecting glucose metabolism were measured. Locomotor activity was detected in an open-field test. S-phenylpiracetam treatment significantly decreased body weight gain and fat mass increase in the obese Zucker rats and in the WD-fed mice. In addition, S-phenylpiracetam reduced the plasma glucose and leptin concentration and lowered hyperglycemia in a glucose tolerance test in both the mice and the rats. S-phenylpiracetam did not influence locomotor activity in the obese Zucker rats or in the WD-fed mice. The results demonstrate that S-phenylpiracetam reduces body weight gain and improves adaptation to hyperglycemia without stimulating locomotor activity. Our findings suggest that selective DAT inhibitors, such as S-phenylpiracetam, could be potentially useful for treating obesity in patients with metabolic syndrome with fewer adverse health consequences compared to other anorectic agents. Copyright © 2017. Published by Elsevier Inc.

Exploring factors influencing farmers' willingness to pay (WTP) for a planned adaptation programme to address climatic issues in agricultural sectors.

Science.gov (United States)

Ahmed, Adeel; Masud, Muhammad Mehedi; Al-Amin, Abul Quasem; Yahaya, Siti Rohani Binti; Rahman, Mahfuzur; Akhtar, Rulia

2015-06-01

This study empirically estimates farmers' willingness to pay (WTP) for a planned adaptation programme for addressing climate issues in Pakistan's agricultural sectors. The contingent valuation method (CVM) was employed to determine a monetary valuation of farmers' preferences for a planned adaptation programme by ascertaining the value attached to address climatic issues. The survey was conducted by distributing structured questionnaires among Pakistani farmers. The study found that 67 % of respondents were willing to pay for a planned adaptation programme. However, several socioeconomic and motivational factors exert greater influence on their willingness to pay (WTP). This paper specifies the steps needed for all institutional bodies to better address issues in climate change. The outcomes of this paper will support attempts by policy makers to design an efficient adaptation framework for mitigating and adapting to the adverse impacts of climate change.

Issues facing the U. S. mirror program

Energy Technology Data Exchange (ETDEWEB)

George, T.V.

1978-07-01

Some of the current issues associated with the U.S. Magnetic Mirror Program are analyzed. They are presented as five separate papers entitled: (1) Relevant Issues Broughtup by the Mirror Reactor Design Studies. (2) An Assessment of the Design Study of the 1 MeV Neutral Beam Injector Required for a Tandem Mirror Reactor. (3) The Significance of the Radial Plasma Size Measured in Units of Ion Gyroradii in Tandem Mirrors and Field Reversed Mirrors. (4) Producing Field Reversed Mirror Plasmas by Methods used in Field Reversed Theta Pinch. (5) RF Stoppering of Mirror Confined Plasma.

Evaluation of maize S2 lines in test cross combinations I : flowering and morphological traits

International Nuclear Information System (INIS)

Rahman, H.; Shah, A.Z.; Shah, S.M.A.; Khalil, I.H.

2010-01-01

This research work was conducted at N.W.F.P. Agricultural University, Peshawar to test 24 maize S2 lines using line x tester analysis. Data were recorded on days to 50% pollen shedding and silking, anthesis silking interval (ASI), ear height and plant height. Results revealed highly significant differences among the testcrosses for all these parameters. Maximum days to silking (62) were observed for TC-13, using WD 2x8 as a tester, while SCA for day to silking was recorded 3.15. Maximum days to anthesis were observed (60) for TC-36, using WD 3x6 as a tester. Maximum value (3 days) for anthesis silking interval was observed for TC-13, using WD 2x8 as a tester, while SCA for anthesis silking interval was recorded to be 1.60 days. Maximum ear height (82cm) was observed for the TC-21, using WD 3x6 as a tester, while SCA for ear height was 1.5 cm. Maximum plant eight (161 cm) was observed for TC-21, using WD 3x6 as a tester, while SCA for plant height was found to be -17.8 cm. These testcrosses are recommended to be included in further breeding programs for developing maize germplasm with earlier flowering and desirable plant and ear height attributes. (author)

Approach to Issues in Planning and Operation of Railway BOT Projects

Institute of Scientific and Technical Information of China (English)

Zhao Xianghong; Chen Min

2009-01-01

As an internationally popular mode of public infrastructures' investment,construction and operation,BOT (build-operate-transfer) has been successfully applied in some countries and regions of the world for their infrastructures' construction and playing an important role in promoting the construction of public infrastructures.The Ministry of Railways clearly proposed in its Suggestions for Implementation of Encouraging,Supporting and Guiding Participation of Non-public-owned Economy in Railway Construction and Operation that it was necessary to study and take for reference multiple modes of public infrastructures'investment,construction and operation including BOT.It is more complicated and risky for the process of planning and operation of BOT projects.The paper takes for reference the domestic and foreign experiences in the operation of BOT projects,analyzes the issues that will arise such as risk control in implementing railway BOT projects,employment of professional consultants,financing coordination,tariff making,non-commercial subsidy,as well as operation and management,and puts forward corresponding suggestions for these issues.

Experimental investigations on the fluid flow through an asymmetric rod bundle (W/D = 1.026)

International Nuclear Information System (INIS)

Rehme, K.

1982-05-01

Measurements of the distributions of the mean velocity, the wall shear stresses and the turbulence were performed in a wall subchannel of a rod bundle of four parallel rods arranged asymmetrically in a rectangular channel (P/D = 1.07, W/D = 1.026). The Reynolds number of this investigation was Re = 5.46 x 10 4 . The experimental results show that the momentum transport is highly anisotropic especially in the gaps of the rod bundle. Influences of secondary flow cannot be detected in the distribution of the time-mean velocity, however, such influences are found in the distributions of the turbulence intensities and the kinetic energy of turbulence. The comparison between experimental wall shear stress distributions and those calculated with the VELASCO-code shows discrepancies especially in the gap between the rod and channel walls. (orig.) [de

China-U.S. Relations: Current Issues and Implications for U.S. Policy

National Research Council Canada - National Science Library

Dumbaugh, Kerry

2007-01-01

.... policy makers have adopted tougher stances on issues involving China and U.S.-China relations, concerned about the impact of the PRC's strong economic growth and a more assertive international diplomacy...

1994 Site Development Plan: A plan with vision

Energy Technology Data Exchange (ETDEWEB)

1994-07-01

The 1994 Lawrence Livermore National Laboratory Site Development Plan has been developed during a period of great change and uncertainty. Our goal is to make possible the best use of the Laboratory`s resources to meet shifting national priorities in the post-Cold War world. Site Planning is an important component of the overall Laboratory strategic planning process. This plan focuses on opportunities for the Laboratory as well as on key site development issues including facility construction, redevelopment and reuse, site accessibility, and security. A major challenge is to achieve sufficient stability in the site planning and execution so that the processes of construction can occur efficiently while at the same time providing sufficient flexibility in site facilities so that a range of changing national needs can be accommodated. We are closely coupled to the DOE strategic planning process to meet this challenge.

Jordan: U.S. Relations and Bilateral Issues

Science.gov (United States)

2007-01-25

bring about a compromise solution to Iraq’s sectarian violence and insurgency. Nevertheless, should the Administration heed the main recommendations of...Committee (NLC), a New York-based human rights advocacy group, issued a 161-page report alleging sweatshop -like conditions in 28 out of 100 Qualified

Quality-assurance plan for groundwater activities, U.S. Geological Survey, Washington Water Science Center

Science.gov (United States)

Kozar, Mark D.; Kahle, Sue C.

2013-01-01

This report documents the standard procedures, policies, and field methods used by the U.S. Geological Survey’s (USGS) Washington Water Science Center staff for activities related to the collection, processing, analysis, storage, and publication of groundwater data. This groundwater quality-assurance plan changes through time to accommodate new methods and requirements developed by the Washington Water Science Center and the USGS Office of Groundwater. The plan is based largely on requirements and guidelines provided by the USGS Office of Groundwater, or the USGS Water Mission Area. Regular updates to this plan represent an integral part of the quality-assurance process. Because numerous policy memoranda have been issued by the Office of Groundwater since the previous groundwater quality assurance plan was written, this report is a substantial revision of the previous report, supplants it, and contains significant additional policies not covered in the previous report. This updated plan includes information related to the organization and responsibilities of USGS Washington Water Science Center staff, training, safety, project proposal development, project review procedures, data collection activities, data processing activities, report review procedures, and archiving of field data and interpretative information pertaining to groundwater flow models, borehole aquifer tests, and aquifer tests. Important updates from the previous groundwater quality assurance plan include: (1) procedures for documenting and archiving of groundwater flow models; (2) revisions to procedures and policies for the creation of sites in the Groundwater Site Inventory database; (3) adoption of new water-level forms to be used within the USGS Washington Water Science Center; (4) procedures for future creation of borehole geophysics, surface geophysics, and aquifer-test archives; and (5) use of the USGS Multi Optional Network Key Entry System software for entry of routine water-level data

Repair and maintenance costs of 4WD tractors and self propelled combine harvesters in Italy

Directory of Open Access Journals (Sweden)

Aldo Calcante

2013-09-01

Full Text Available Purchasing and maintaining tractors and operating machines are two of the most considerable costs of the agricultural sector, which includes farm equipment manufacturers, farm contractors and farms. In this context, repair and maintenance costs (R&M costs generally constitute 10-15% of the total costs related to agricultural equipment and tend to increase with the age of the equipment; hence, an important consideration in farm management is the optimal time for equipment replacement. Classical, R&M cost estimation models, calculated as a function of accumulated working hours, are usually developed by ASAE/ASABE for the United States operating conditions. However, R&M costs are strongly influenced by farming practices, operative conditions, crop and soil type, climatic conditions, etc. which can be specific for individual countries. In this study, R&M cost model parameters were recalculated for the current Italian situation. For this purpose, data related to the R&M costs of 100 4WD tractors with engine power ranging from 59 to 198 kW, and of 20 SP combine harvesters (10 straw walkers combines and 10 axial flow combines with engine power ranging from 159 to 368 kW working in Italy were collected. According to the model, which was obtained by interpolating the data through a two-parameter power function (proposed by ASAE/ASABE, the R&M cost incidence on the list price of Italian tractors at 12,000 working hours (estimated life of the machines was 48.6%, as compared with 43.2% calculated through the most recent U.S. model while, for self propelled combine harvesters, the R&M cost incidence at 3,000 working hours was 23.1 % as compared with 40.2% calculated through the same U.S. model.

Missense mutations in the WD40 domain of AHI1 cause non-syndromic retinitis pigmentosa.

Science.gov (United States)

Nguyen, Thanh-Minh T; Hull, Sarah; Roepman, Ronald; van den Born, L Ingeborgh; Oud, Machteld M; de Vrieze, Erik; Hetterschijt, Lisette; Letteboer, Stef J F; van Beersum, Sylvia E C; Blokland, Ellen A; Yntema, Helger G; Cremers, Frans P M; van der Zwaag, Paul A; Arno, Gavin; van Wijk, Erwin; Webster, Andrew R; Haer-Wigman, Lonneke

2017-09-01

Recent findings suggesting that Abelson helper integration site 1 ( AHI1 ) is involved in non-syndromic retinal disease have been debated, as the functional significance of identified missense variants was uncertain. We assessed whether AHI1 variants cause non-syndromic retinitis pigmentosa (RP). Exome sequencing was performed in three probands with RP. The effects of the identified missense variants in AHI1 were predicted by three-dimensional structure homology modelling. Ciliary parameters were evaluated in patient's fibroblasts, and recombinant mutant proteins were expressed in ciliated retinal pigmented epithelium cells. In the three patients with RP, three sets of compound heterozygous variants were detected in AHI1 (c.2174G>A; p.Trp725* and c.2258A>T; p.Asp753Val, c.660delC; p.Ser221Glnfs*10 and c.2090C>T; p.Pro697Leu, c.2087A>G; p.His696Arg and c.2429C>T; p.Pro810Leu). All four missense variants were present in the conserved WD40 domain of Jouberin, the ciliary protein encoded by AHI1 , with variable predicted implications for the domain structure. No significant changes in the percentage of ciliated cells, nor in cilium length or intraflagellar transport were detected. However, expression of mutant recombinant Jouberin in ciliated cells showed a significantly decreased enrichment at the ciliary base. This report confirms that mutations in AHI1 can underlie autosomal recessive RP. Moreover, it structurally and functionally validates the effect of the RP-associated AHI1 variants on protein function, thus proposing a new genotype-phenotype correlation for AHI1 mutation associated retinal ciliopathies. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

NRC program for the resolution of generic issues related to nuclear power plants. (Includes plans for the resolution of ''unresolved safety issues'' pursuant to Section 210 of the Energy Reorganization Act of 1974, as amended)

International Nuclear Information System (INIS)

1977-12-01

This report provides a description of the Nuclear Regulatory Commission's Program for the Resolution of Generic Issues Related to Nuclear Power Plants. The NRC program is of considerably broader scope than the ''Unresolved Safety Issues Plan'' required by Section 210. The NRC program does include plans for the resolution of ''Unresolved Safety Issues''; however, in addition, it includes generic tasks for the resolution of environmental issues, for the development of improvements in the reactor licensing process and for consideration of less conservative design criteria or operating limitations in areas where over conservatisms may be unnecessarily restrictive or costly

White plan and crisis management. Help guide for the elaboration of extended white plans and of white plans for health establishments. Issue 2006, appendix to circular nr DHOS/CGR/2006/401 of 2006 September 14

International Nuclear Information System (INIS)

2006-01-01

White plans are specific emergency plans to be implemented in public and private health establishments. While introducing necessary modifications and taking public health policy effects into account, this document first defines crises and their management (levels of intervention from the local to the national level, typology of emergency plans, emergency medical chain, extended white plans). The second part proposes a set of sheets which aim to be a support in the elaboration of the extended white plan and of the white plan. The third part, based on professional contributions and lessons learned, addresses two important issues: firstly, the crisis management exercise, and secondly the hospital under tension and white plan triggering thresholds

Ztráta bydlení a možnost reintegrace

Czech Academy of Sciences Publication Activity Database

Mikeszová, Martina

2011-01-01

Roč. 22, č. 16 (2011), s. 16-19 ISSN 1213-6581 R&D Projects: GA MMR WD-05-07-3 Institutional research plan: CEZ:AV0Z70280505 Keywords : housing * homelessness * social policy Subject RIV: AO - Sociology, Demography

Issues of the '90s

International Nuclear Information System (INIS)

Barber, C.F.

1990-01-01

Milt Ward has asked me to say a few words on two issues which have been high on the AMC regulatory agenda for many years--access to the public lands and the environment. Both lie at the interface between mining, an essential industrial activity, and the protection and conservation of other resource values. The operation of the mining law of 1872 has been under public scrutiny for many years. Many in the mining industry have cooperated in the development of workable regulations, realizing that regulation could have the effect of ameliorating the pressure for additional withdrawals or legislation limiting access to the public lands for exploration. Thus by the 1980s, the activities of some explorers and miners which in an earlier day gave rise to justified concern, all but disappeared from Public Lands. There can be no doubt that environmental issues are the most pressing issues confronting the domestic mining and minerals processing industries. Leaders in government willing to take a position on the appropriate balance between measurable costs and presumed benefits of environmental regulations are rare. Thus those of us involved in the creation of wealth for the use and benefit of our fellow men must commit ourselves to the unending task of communicating the benefits of our activities to the public which enjoy those benefits. The mining industry is an industry essential to our way of life. That fact should give us the continuing confidence to demonstrate and to communicate that we are responsible guardians of the world's resources

Mezi-krajské a vnitro-krajské rozdíly v dostupnosti tržního nájemního bydlení

Czech Academy of Sciences Publication Activity Database

Lux, Martin; Mikeszová, Martina

2009-01-01

Roč. 12, č. 4 (2009), s. 46-48 ISSN 1212-0855 R&D Projects: GA MMR WD-05-07-3 Institutional research plan: CEZ:AV0Z70280505 Keywords : regional differences * housing affordability * rental housing Subject RIV: AO - Sociology, Demography

233S Decommissioning Project Environmental Control Plan

International Nuclear Information System (INIS)

Zoric, J.P.

2000-01-01

This Environmental Control Plan is for the 233S Decommissioning activities conducted under the removal action report for the 233S Decontamination and Demolition Project. The purpose of this ECP is to identify environmental requirements for the 233S project. The ECP is a compilation of existing environmental permit conditions, regulatory requirements, and environmental requirements applicable to the specific project or functional activity

Site Selection, Acquisition, and Planning for Aquaculture in Dredged Material Containment Areas

Science.gov (United States)

1993-08-01

LCUIRSETTIWVIN Figure ACUAT 6. Fowhr o ei gnpoeuefrstln n nta trg RAEQUREDt S RACErmadWd 98 18~RE FORte 2- SiteA Selej) Site characteristics Table 1 lists...seeds, spores, organisms, etc.) (5) Effects on preserves, etc. Imvact f Attraction of vectors ( insects or rodents) due to creation of favorable

Water temperature issues in the 90's and beyond

International Nuclear Information System (INIS)

Railsback, S.F.

1993-01-01

Water temperature issues are expected to receive increasing attention in the 1990s. Temperature impacts are among the most common and most expensive environmental issues requiring mitigation at water projects, but few changes in mitigation technologies and little research have occurred in the past decade. Water projects alter water temperatures because the heat balances in reservoirs and in streams with altered flows are significantly different from natural. Several emerging environmental and regulatory concerns and issues are likely to focus additional attention on temperature. Climate change, should it occur as predicted, can be expected to worsen many water temperature problems and complicate the determination of appropriate mitigation for water projects. The purposes of this paper are to review current water temperature issues and mitigation methods, to identify new and future temperature issues, and to identify research needs

ECOWindS Joint Action Plan - Guidelines for Implementation

DEFF Research Database (Denmark)

2015-01-01

The Joint Action Plan (JAP) is a deliverable of the European Clusters for Offshore Wind Servicing (ECOWindS) project Work Package 4 (WP4) “Joint Action Plan”. It presents a plan of action or a roadmap for research, development, and innovation (RDI) for the Offshore Wind Service (OWS) industry. Th...

An Explanation on the Tenth-Five-Year Plan of China’s Auto Industry

Institute of Scientific and Technical Information of China (English)

2002-01-01

<正> The Tenth-Five-Year-Plan of the auto industry recently issued has made an analysis on the market demand, development environment and situation that the auto industry will face and advanced the idea for solving contractions and problems, taking the restructuring as motif. Compared with the previous medium-and-long-term programs, the plan is more macroscopic, strategical,

The transportation institutional plan: Cooperative planning for NWPA transportation

International Nuclear Information System (INIS)

Denny, S.H.; Livingston-Behan, E.A.

1987-01-01

The Transportation Institutional Plan, published in 1986 by the U.S. Department of Energy's Office of Civilian Radioactive Waste Management (OCRWM), defines a process for effective interaction among those who may be affected by transportation activities conducted under provisions of the Nuclear Waste Policy Act of 1982 (NWPA). The Plan describes formal mechanisms for identifying, addressing, and resolving specific transportation issues. An appendix to the Plan includes detailed discussion of the following transportation issues: (1) the transportation of defense waste; (2) prenotification; (3) physical and rail shipments; (4) highway routing; (5) rail routing; (6) inspection and enforcement for highway and rail shipments; (7) emergency response; (8) liability coverage for transportation to NWPA facilities; (9) cask design and testing; (10) overweight truck shipments; (11) rail service analysis; (12) mixture of transportation modes; (13) transportation infrastructure improvements; (14) OCRWM training standards; (15) transportation operational procedures; and (16) State, Tribal, and local regulation of transportation. The OCRWM's intent is to provide an open accounting of planning, to identify opportunities for public involvement in program activities, and to foster communication and negotiation in the cooperative development of a safe, efficient, and cost-effective NWPA transportation program

U.S. Strategic Nuclear Forces: Background, Developments, and Issues

Science.gov (United States)

2017-02-10

Cost $85 Billion,” Bloomberg News , September 6, 2016. 62 Aaron Mehta, “Planned ICBM Replacement To Move Forward Without Consensus,” Defense News ...bombers, consistent with the terms of the New START Treaty, it also plans to develop new delivery systems for deployment over the next 20-30 years. The 115...1,550 deployed warheads in 2018, after the New START Treaty completes implementation. At the present time, the U.S. land-based ballistic missile force

Ternary WD40 repeat-containing protein complexes: evolution, composition and roles in plant immunity

Directory of Open Access Journals (Sweden)

Jimi C. Miller

2016-01-01

Full Text Available Plants, like mammals, rely on their innate immune system to perceive and discriminate among the majority of their microbial pathogens. Unlike mammals, plants respond to this molecular dialogue by unleashing a complex chemical arsenal of defense metabolites to resist or evade pathogen infection. In basal or non-host resistance, plants utilize signal transduction pathways to detect non-self, damaged-self and altered-self-associated molecular patterns and translate these danger signals into largely inducible chemical defenses. The WD40 repeat (WDR-containing proteins Gβ and TTG1 are constituents of two independent ternary protein complexes functioning at opposite ends of a plant immune signaling pathway. Gβ and TTG1 are also encoded by single-copy genes that are ubiquitous in higher plants, implying the limited diversity and functional conservation of their respective complexes. In this review, we summarize what is currently known about the evolutionary history of these WDR-containing ternary complexes, their repertoire and combinatorial interactions, and their downstream effectors and pathways in plant defense.

78 FR 51754 - Request To Modify License by Replacing Security Plan With New Radiation Safety Plan; U.S...

Science.gov (United States)

2013-08-21

... Replacing Security Plan With New Radiation Safety Plan; U.S. Department of the Army, Jefferson Proving... security plan with a new radiation safety plan. DATES: Submit comments by September 20, 2013. Requests for.... The proposed change is to modify License Condition No. 12 D which refers to the security plan of...

'Morals can not be drawn from facts but guidance may be': the early life of W.D. Hamilton's theory of inclusive fitness.

Science.gov (United States)

Swenson, Sarah A

2015-12-01

W.D. Hamilton's theory of inclusive fitness saw the evolution of altruism from the point of view of the gene. It was at heart a theory of limits, redefining altruistic behaviours as ultimately selfish. This theory inspired two controversial texts published almost in tandem, E.O. Wilson's Sociobiology: The New Synthesis (1975) and Richard Dawkins's The Selfish Gene (1976). When Wilson and Dawkins were attacked for their evolutionary interpretations of human societies, they claimed a distinction between reporting what is and declaring what ought to be. Can the history of sociobiological theories be so easily separated from its sociopolitical context? This paper draws upon unpublished materials from the 1960s and early 1970s and documents some of the ways in which Hamilton saw his research as contributing to contemporary concerns. It pays special attention to the 1969 Man and Beast Smithsonian Institution symposium in order to explore the extent to which Hamilton intended his theory to be merely descriptive versus prescriptive. From this, we may see that Hamilton was deeply concerned about the political chaos he perceived in the world around him, and hoped to arrive at a level of self-understanding through science that could inform a new social order.

TOWARDS DEVELOPING A SUSTAINABLE HERITAGE TOURISM AND CONSERVATION ACTION PLAN FOR IRBID’S HISTORIC CORE

Directory of Open Access Journals (Sweden)

Naif Adel Haddad

2016-11-01

Full Text Available Tal (mount Irbid in Irbid city, Jordan, with its continuous human occupation from the Bronze Age until the present, demonstrates the main landmark that has guided the spread of the urban growth of the city. The outcome of studies carried out at Irbid’s historic core, in relation to assessing the loss and degradation of the core’s cultural heritage, shall be analyzed, investigated, and discussed, as also concerns, obstacles, and issues of sustainability to this urban heritage conservation and tourism planning. The paper starts by defining the urban heritage for the historic core, which tends to be set aside, in the city’s rapid development. Actually, the remaining historic buildings can also provide the necessary inter-relationships between the historic core areas and the wider urban context to achieve a sustainable and integrated tourism and conservation action plan for the three heritage neighborhoods around the Tal, while building on tourism opportunities and taking into consideration the needs and the vital role of the local community. The paper concludes that urban heritage conservation and protection of the integrity and identity of the historic core city fabric can assist in its branding, promotion, and management in ways that could enhance the local community belonging, quality of everyday lifestyle, and visitors' experience.

Improvement Plans of Fermilab’s Proton Accelerator Complex

Science.gov (United States)

Shiltsev, Vladimir

2017-09-01

The flagship of Fermilab’s long term research program is the Deep Underground Neutrino Experiment (DUNE), located Sanford Underground Research Facility (SURF) in Lead, South Dakota, which will study neutrino oscillations with a baseline of 1300 km. The neutrinos will be produced in the Long Baseline Neutrino Facility (LBNF), a proposed new beam line from Fermilab’s Main Injector. The physics goals of the DUNE require a proton beam with a power of some 2.4 MW at 120 GeV, which is roughly four times the current maximum power. Here I discuss current performance of the Fermilab proton accelerator complex, our plans for construction of the SRF proton linac as key part of the Proton Improvement Plan-II (PIP-II), outline the main challenges toward multi-MW beam power operation of the Fermilab accelerator complex and the staged plan to achieve the required performance over the next 15 years.

Planning for an ageing population: strategic considerations

LENUS (Irish Health Repository)

O'Shea, Dr Eamon

2005-01-01

This report presents both the proceedings of the Council’s conference, Planning for an Ageing Population: Strategic Considerations, and the Council’s discussion paper, ‘The Older Population: Information Issues and Deficits’, which was introduced at that conference.\\r\

U.S. Arctic Voyage Planning Guide (AVPG)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — The Arctic Voyage Planning Guide is a compilation of official U.S. Government information and references to sources of information that may be consulted by mariners...

Issues in regional planning and development in Nigeria

Directory of Open Access Journals (Sweden)

Oladayo Ramon Ibrahim

2017-10-01

Full Text Available Till date,Nigeria can not boast of a specific, well-formulated, clear regional development policy framework despite several urban planning, development and governance initiatives including passage of regulations at both federal and state government levels that have been undertaken since independence by successive post- colonial governments. Most of the country's claims of regional development are products of other policies, and intentions, which do not have any bearing on, deliberate regional planning policies. Policy and decision-making on development planning often do not incorporate the implications of the ways in which we use land and the consequences for different places (economic planning. The neglect of place, in particular, the way that different policies combine to affect places in different ways (regional planning, has contributed to a range of negative economic, social and environmental outcomes. This paper relies mainly on the secondary data and literature exploration to demonstrate that the little role accorded to spatial planning, especially, regional planning, in the development efforts is largely responsible for the underdevelopment, imbalance, and inequalities in the country, as well as poverty of the citizens. The conclusion of the paper is that regional planning should be an integral part and complementary to economic planning in the national development planning of the country. For regional planning to aid in the development of the country and promote the well-being of the citizens, appropriate recommendations have been included in the paper.

Schedule optimization study implementation plan

International Nuclear Information System (INIS)

1993-11-01

This Implementation Plan is intended to provide a basis for improvements in the conduct of the Environmental Restoration (ER) Program at Hanford. The Plan is based on the findings of the Schedule Optimization Study (SOS) team which was convened for two weeks in September 1992 at the request of the U.S. Department of Energy (DOE) Richland Operations Office (RL). The need for the study arose out of a schedule dispute regarding the submission of the 1100-EM-1 Operable Unit (OU) Remedial Investigation/Feasibility Study (RI/FS) Work Plan. The SOS team was comprised of independent professionals from other federal agencies and the private sector experienced in environmental restoration within the federal system. The objective of the team was to examine reasons for the lengthy RI/FS process and recommend ways to expedite it. The SOS team issued their Final Report in December 1992. The report found the most serious impediments to cleanup relate to a series of management and policy issues which are within the control of the three parties managing and monitoring Hanford -- the DOE, U.S. Environmental Protection Agency (EPA), and the State of Washington Department of Ecology (Ecology). The SOS Report identified the following eight cross-cutting issues as the root of major impediments to the Hanford Site cleanup. Each of these eight issues is quoted from the SOS Report followed by a brief, general description of the proposed approach being developed

Essential role of the NH2-terminal WD/EPF motif in the phosphorylation-activated protective function of mammalian Hsp27.

Science.gov (United States)

Thériault, Jimmy R; Lambert, Herman; Chávez-Zobel, Aura T; Charest, Gabriel; Lavigne, Pierre; Landry, Jacques

2004-05-28

Hsp27 is expressed at high levels after mild heat shock and contributes to making cells extremely resistant to subsequent treatments. The activity of the protein is regulated at the transcriptional level, but also by phosphorylation, which occurs rapidly during stress and is responsible for causing the dissociation of large 700-kDa Hsp27 oligomers into dimers. We investigated the mechanism by which phosphorylation and oligomerization modulate the protective activity of Chinese hamster Hsp27. In contrast to oligomer dissociation, which only required Ser90 phosphorylation, activation of Hsp27 thermoprotective activity required the phosphorylation of both Ser90 and Ser15. Replacement of Ser90 by Ala90, which prevented the dissociation of the oligomer upon stress, did cause a severe defect in the protective activity. Dissociation was, however, not a sufficient condition to activate the protein because replacement of Ser15 by Ala15, which caused little effect in the oligomeric organization of the protein, also yielded an inactive protein. Analyzes of mutants with short deletions in the NH2 terminus identified the Hsp27 WD/EPF or PF-rich domain as essential for protection, maintenance of the oligomeric structure, and in vitro chaperone activity of the protein. In light of a three-dimensional model of Hsp27 based on the crystallographic structure of wheat Hsp16.9, we propose that the conserved WD/EPF motif of mammalian Hsp27 mediates important intramolecular interactions with hydrophic surfaces of the alpha-crystallin domain of the protein. These interactions are destabilized by Ser90 phosphorylation, making the motif free to interact with heterologous molecular targets upon the additional phosphorylation of the nearby Ser15.

Structure of Life’s Plans of Socially Maladjusted Young People

Directory of Open Access Journals (Sweden)

Marcin Szulc

2013-12-01

Full Text Available The plans creating is a sign of human activity on the conscious level. Plans prove the creativity of the man. Plans permit to see the man as the active author. Life plans are modified by life experiences. The aim of research was to illustrate a structure of life plans of socially maladjusted young people. The study used B.R Little’s Personal Project Analyses (PPA. The studies show that socially maladjusted adolescents differ in the assessment of plans and evaluation of youth in the control group.

1997 U.S. Department of Energy Strategic Plan

Energy Technology Data Exchange (ETDEWEB)

None,

1997-09-01

With the end of the Cold War and the election of President Clinton, the Department of Energy (DOE) set a new course which began with the publication of its first departmental strategic plan in April 1994. Entitled ``Fueling a Competitive Economy, it provided the framework and shared vision for meeting responsibilities in energy, national security, environmental quality, and science and technology. The strategic plan was the guidepost for the formulation of the Department`s FY 1996, FY 1997, and FY 1998 budgets and was critical to the development of the Department`s Strategic Alignment Initiative, designed to save $1.7 billion over five years. This current plan, which has been significantly improved through a very close consultation process with Congress and customers stakeholders, takes DOE to the next important performance level by being more directly linked to actions and results. It defines a strategic goal for each of the Department`s four business lines and, in the spirit of the Government Performance and Results Act and the National Performance Review, identifies a fifth goal addressing corporate management. Reengineering the business practices, managing for results, being open with neighbors and stakeholders, and ensuring the safety and health of DOE workers and the public are, and will continue to be, among the highest of priorities. Over the coming years, DOE plans to achieve their strategic goals through specific identifiable strategies. Each business line has clear objectives and straightforward ways of defining whether DOE has succeeded in meeting those objectives.

The main issues preventing Kosovo’s economic development

Directory of Open Access Journals (Sweden)

Demir Lima

2017-11-01

Full Text Available This study provides an analysis of several problematic factors preventing Kosovo’s economic development. Several sectors that could have been the main pillars of economic development, such as manufacturing, energy, mines and minerals, and other economic sectors have been neglected from the development by domestic institutions or were used clandestinely by certain interest groups, whose focus was not in the development of the country but rather their personal gain. Trade remained the preferred activity throughout these years, which cannot be considered a beneficial sector for economic development, as much as manufacturing, which remains to date as Kosovo’s most underdeveloped sector. As long as Kosovo’s exports cover only 12% of total imports, no economic growth can be expected. Kosovo’s failure to attract strategic investors in years, which could open new jobs, has also contributed its lack of sufficient economic development. Thus, the most concerning issue during this period is the decline in foreign direct investments, which were expected to increase after the declaration of independence. In the lack of a long-term development strategy for certain sectors or priority activities, such as mines, energy, industry etc., there is no progress in the country's economic development. The main issue is that we should only favor those activities or identify segments where we have competitive advantages compared to other countries.

DDoS Attacks in Cloud Computing: Issues, Taxonomy, and Future Directions

OpenAIRE

Somani, Gaurav; Gaur, Manoj Singh; Sanghi, Dheeraj; Conti, Mauro; Buyya, Rajkumar

2015-01-01

Security issues related to the cloud computing are relevant to various stakeholders for an informed cloud adoption decision. Apart from data breaches, the cyber security research community is revisiting the attack space for cloud-specific solutions as these issues affect budget, resource management, and service quality. Distributed Denial of Service (DDoS) attack is one such serious attack in the cloud space. In this paper, we present developments related to DDoS attack mitigation solutions i...

Application of MRIL-WD (Magnetic Resonance Imaging Logging While Drilling) for irreducible water saturation, total reservoir, free-fluid, bound-fluid porosity measurements and its value for the petrophysical analysis of RT/RM data from the Shah Deniz well

Science.gov (United States)

Amirov, Elnur

2016-04-01

Sperry-Sun (Sperry Drilling Services) is the leader in MWD/LWD reliability, has developed the industry's first LWD NMR/MRIL-WD (nuclear magnetic resonance) tool. The MRIL-WD (magnetic resonance imaging logging-while-drilling) service directly measures the T1 component of hydrogen in subsurface rock units while drilling to obtain total reservoir porosity and to dissect the observed total porosity into its respective components of free fluid and bound fluid porosity. These T1 data are used to secure accurate total, free-fluid, capillary-bound water, and clay-bound water porosity of the reservoir sections which can be drilled in the several Runs. Over the last decade, results from Magnetic Resonance Imaging logs (NMR) have added significant value to petrophysical analysis and understanding by providing total, free-fluid and bound-fluid porosities, combined with fluid typing capabilities. With MRIL-WD very valuable Real-Time or Recorded Memory data/information is now available during or shortly after the drilling operation (formation properties measurement can be taken right after a drill bit penetration), while trip in and trip out as well. A key point in utilizing MRIL in an LWD environment is motion-tolerant measurements. Recent MRIL-WD logging runs from the Shah Deniz wells located in the Khazarian-Caspian Sea of the Azerbaijan Republic helped to delineate and assess hydrocarbon bearing zones. Acquired results demonstrate how MRIL data can be acquired while-drilling and provide reliable/high quality measurements. Magnetic Resonance Imaging logs at some developments wells have become a cornerstone in formation evaluation and petrophysical understanding. By providing total, free-fluid, and bound-fluid porosities together with fluid typing, MRIL results have significantly added to the assessment of reservoirs. In order to reduce NPT (Non-Productive Time) and save the rig operations time, there is always the desire to obtain logging results as soon as possible

Wildland Fire Management Plan

Energy Technology Data Exchange (ETDEWEB)

Schwager, K. [Brookhaven National Lab. (BNL), Upton, NY (United States)

2017-09-30

The Wildland Fire Management Plan (FMP) for Brookhaven National Lab (BNL) is written to comply with Department of Energy (DOE) Integrated Safety Management Policy; Federal Wildland Fire Management Policy and Program Review; and Wildland and Prescribed Fire Management Policy and Implementation Procedures Reference Guide. This current plan incorporates changes resulting from new policies on the national level as well as significant changes to available resources and other emerging issues, and replaces BNL's Wildland FMP dated 2014.

Loss of γ-tubulin, GCP-WD/NEDD1 and CDK5RAP2 from the Centrosome of Neurons in Developing Mouse Cerebral and Cerebellar Cortex

International Nuclear Information System (INIS)

Yonezawa, Satoshi; Shigematsu, Momoko; Hirata, Kazuto; Hayashi, Kensuke

2015-01-01

It has been recently reported that the centrosome of neurons does not have microtubule nucleating activity. Microtubule nucleation requires γ-tubulin as well as its recruiting proteins, GCP-WD/NEDD1 and CDK5RAP2 that anchor γ-tubulin to the centrosome. Change in the localization of these proteins during in vivo development of brain, however, has not been well examined. In this study we investigate the localization of γ-tubulin, GCP-WD and CDK5RAP2 in developing cerebral and cerebellar cortex with immunofluorescence. We found that γ-tubulin and its recruiting proteins were localized at centrosomes of immature neurons, while they were lost at centrosomes in mature neurons. This indicated that the loss of microtubule nucleating activity at the centrosome of neurons is due to the loss of γ-tubulin-recruiting proteins from the centrosome. RT-PCR analysis revealed that these proteins are still expressed after birth, suggesting that they have a role in microtubule generation in cell body and dendrites of mature neurons. Microtubule regrowth experiments on cultured mature neurons showed that microtubules are nucleated not at the centrosome but within dendrites. These data indicated the translocation of microtubule-organizing activity from the centrosome to dendrites during maturation of neurons, which would explain the mixed polarity of microtubules in dendrites

Stealing the spotlight: CUL4-DDB1 ubiquitin ligase docks WD40-repeat proteins to destroy

Directory of Open Access Journals (Sweden)

Zhang Hui

2007-02-01

Full Text Available Abstract Recent investigation of Cullin 4 (CUL4 has ushered this class of multiprotein ubiquitin E3 ligases to center stage as critical regulators of diverse processes including cell cycle regulation, developmental patterning, DNA replication, DNA damage and repair, and epigenetic control of gene expression. CUL4 associates with DNA Damage Binding protein 1 (DDB1 to assemble an ubiquitin E3 ligase that targets protein substrates for ubiquitin-dependent proteolysis. CUL4 ligase activity is also regulated by the covalent attachment of the ubiquitin-like protein NEDD8 to CUL4, or neddylation, and the COP9 signalosome complex (CSN that removes this important modification. Recently, multiple WD40-repeat proteins (WDR were found to interact with DDB1 and serve as the substrate-recognition subunits of the CUL4-DDB1 ubiquitin ligase. As more than 150–300 WDR proteins exist in the human genome, these findings impact a wide array of biological processes through CUL4 ligase-mediated proteolysis. Here, we review the recent progress in understanding the mechanism of CUL4 ubiquitin E3 ligase and discuss the architecture of CUL4-assembled E3 ubiquitin ligase complexes by comparison to CUL1-based E3s (SCF. Then, we will review several examples to highlight the critical roles of CUL4 ubiquitin ligase in genome stability, cell cycle regulation, and histone lysine methylation. Together, these studies provide insights into the mechanism of this novel ubiquitin ligase in the regulation of important biological processes.

Government Performance and Results Act: Performance plan FY 1999, U.S. Nuclear Regulatory Commission. Volume 1

Energy Technology Data Exchange (ETDEWEB)

Fuches, J.L.

1998-02-01

The Nuclear Regulatory Commission`s (NRC) strategic plan [NUREG-1614, Vol. 1, September 1997] establishes a strategic framework that will guide future decision-making and will help the NRC continue to meet its responsibility for protecting public health and safety, promoting the common defense and security, and protecting the environment. This performance plan complements the agency`s strategic plan by setting annual goals with measurable target levels of performance for FY 1999, as required by the Government Performance and Results Act. No significant contribution was made to the preparation of the performance plan by any non-Federal entity. However, a contractor was used to help facilitate discussions and resolution of issues. Within six months after the close of FY 1999, the NRC will submit to the President and the Congress a report on program performance for FY 1999. This performance report will review the success of the agency in achieving the performance goals established for FY 1999. Where those goals have been achieved, the underlying assumptions and strategies will be examined to ensure that continued applicability is warranted in the future. If any of the FY 1999 performance goals are not met, the agency will conduct a thorough analysis of why it did not meet the goal and the actions necessary to meet-the goal in the future. One result of this analysis will be the documentation of plans and schedules for achieving the established performance goal. If the analysis should indicate that the performance goal is impractical or infeasible, the performance report will document why that is the case and what action is recommended.

International Thermonuclear Experimental Reactor U.S. Home Team Quality Assurance Plan

Energy Technology Data Exchange (ETDEWEB)

Sowder, W. K.

1998-10-01

The International Thermonuclear Experimental Reactor (ITER) project is unique in that the work is divided among an international Joint Central Team and four Home Teams, with the overall responsibility for the quality of activities performed during the project residing with the ITER Director. The ultimate responsibility for the adequacy of work performed on tasks assigned to the U.S. Home Team resides with the U.S. Home Team Leader and the U.S. Department of Energy Office of Fusion Energy (DOE-OFE). This document constitutes the quality assurance plan for the ITER U.S. Home Team. This plan describes the controls exercised by U.S. Home Team management and the Performing Institutions to ensure the quality of tasks performed and the data developed for the Engineering Design Activities assigned to the U.S. Home Team and, in particular, the Research and Development Large Projects (7). This plan addresses the DOE quality assurance requirements of 10 CFR 830.120, "Quality Assurance." The plan also describes U.S. Home Team quality commitments to the ITER Quality Assurance Program. The ITER Quality Assurance Program is based on the principles described in the International Atomic Energy Agency Standard No. 50-C-QA, "Quality Assurance for Safety in Nuclear Power Plants and Other Nuclear Facilities." Each commitment is supported with preferred implementation methodology that will be used in evaluating the task quality plans to be submitted by the Performing Institutions. The implementing provisions of the program are based on guidance provided in American National Standards Institute/American Society of Mechanical Engineers NQA-1 1994, "Quality Assurance." The individual Performing Institutions will implement the appropriate quality program provisions through their own established quality plans that have been reviewed and found to comply with U.S. Home Team quality assurance plan commitments to the ITER Quality Assurance Program. The extent of quality program provisions

Functional Characterization of Rare RAB12 Variants and Their Role in Musician’s and Other Dystonias

Directory of Open Access Journals (Sweden)

Eva Hebert

2017-10-01

Full Text Available Mutations in RAB (member of the Ras superfamily genes are increasingly recognized as cause of a variety of disorders including neurological conditions. While musician’s dystonia (MD and writer’s dystonia (WD are task-specific movement disorders, other dystonias persistently affect postures as in cervical dystonia. Little is known about the underlying etiology. Next-generation sequencing revealed a rare missense variant (c.586A>G; p.Ile196Val in RAB12 in two of three MD/WD families. Next, we tested 916 additional dystonia patients; 512 Parkinson’s disease patients; and 461 healthy controls for RAB12 variants and identified 10 additional carriers of rare missense changes among dystonia patients (1.1% but only one carrier in non-dystonic individuals (0.1%; p = 0.005. The detected variants among index patients comprised p.Ile196Val (n = 6; p.Ala174Thr (n = 3; p.Gly13Asp; p.Ala148Thr; and p.Arg181Gln in patients with MD; cervical dystonia; or WD. Two relatives of MD patients with WD also carried p.Ile196Val. The two variants identified in MD patients (p.Ile196Val; p.Gly13Asp were characterized on endogenous levels in patient-derived fibroblasts and in two RAB12-overexpressing cell models. The ability to hydrolyze guanosine triphosphate (GTP, so called GTPase activity, was increased in mutants compared to wildtype. Furthermore, subcellular distribution of RAB12 in mutants was altered in fibroblasts. Soluble Transferrin receptor 1 levels were reduced in the blood of all three tested p.Ile196Val carriers. In conclusion, we demonstrate an enrichment of missense changes among dystonia patients. Functional characterization revealed altered enzyme activity and lysosomal distribution in mutants suggesting a contribution of RAB12 variants to MD and other dystonias.

Recent environment, energy and resources cases and issues in Alberta

Energy Technology Data Exchange (ETDEWEB)

Kruhlak, R.; Naffin, D.K. [McLennan Ross LLP, Edmonton, AB (Canada)

2005-07-01

Significant environmental issues and regulatory proceedings in Alberta were discussed. The Mackenzie Valley Pipeline Project was reviewed in relation to the Deh Cho First Nation's advanced actions in the federal court to enjoin the review panel from proceeding with the review process. The Deh Cho First Nation is seeking a declaration that the plan violates their rights under the Canadian Charter of Rights and Freedoms and the Constitution Act. Various regulatory and government agencies have now developed a plan to coordinate their different regulatory processes and approvals in the Cooperation Plan for the Environmental Impact Assessment and Regulatory Review of the Northern Gas Pipeline project. The Deh Cho allege that they were not afforded the opportunity to participate in the development and implementation of the plan. A review panel plans to proceed once the environmental and social impacts are determined, and the consortiums plan to minimize harm has been submitted. Issues concerning contaminated sites were discussed with reference to Lynnview Ridge, where Imperial Oil and Devon Estates Ltd. built a residential subdivision built on the site of a decommissioned oil storage tank site. Periodic monitoring detected some general concerns, including high lead levels in soil and hydrocarbon vapors. Environmental Protection Orders (EPO) and appeals were discussed, including Imperial and Devon's appeal that the pollution problem should have been addressed through the contaminated sites provision and not the substance release EPO. Several recommendations were made, including better definition processes for liability allocation; a clarification of persons excluded from responsibility; voluntary remediation agreements that limit liability; and environmental site information systems to support due diligence. It was expected that the final set of recommendations will be of use to all jurisdictions in Canada. Regulatory issues concerning public safety were

Integrating stakeholders' issues and concerns into Nirex's technical research

International Nuclear Information System (INIS)

Atherton, Elisabeth

2004-01-01

This note outlines some of the activities that Nirex has undertaken to try and integrate stakeholders' issues and concerns into the technical research we have undertaken and how we are attempting to address their issues. Nirex arranges a range of dialogue activities including workshops, meetings, interviews and focus groups with a wide range of stakeholders. These events are coordinated under what is called the Nirex Involvement Programme. The feedback and inputs we have received at these events have been used to influence the work that we undertake. Nirex's interactions with stakeholders, particularly members of the public and local councillors in the aftermath of losing the 1997 rock characterisation facility public inquiry at Sellafield, has been fundamental to changing our whole approach. We are now trying to understand people's issues and recognising that Nirex is accountable to a wide constituency of stakeholders, but particularly the general public and their elected representatives. It has also enabled Nirex to attempt to integrate people's issues and concerns into its work programmes. Specific examples of where stakeholders' issues have impacted on the technical work Nirex undertakes are outlined. (author)

31 CFR 546.409 - Credit extended and cards issued by U.S. financial institutions.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Credit extended and cards issued by U... SANCTIONS REGULATIONS Interpretations § 546.409 Credit extended and cards issued by U.S. financial..., charge cards, debit cards, or other credit facilities issued by a U.S. financial institution to a person...

31 CFR 548.409 - Credit extended and cards issued by U.S. financial institutions.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Credit extended and cards issued by U... SANCTIONS REGULATIONS Interpretations § 548.409 Credit extended and cards issued by U.S. financial..., charge cards, debit cards, or other credit facilities issued by a U.S. financial institution to a person...

31 CFR 588.409 - Credit extended and cards issued by U.S. financial institutions.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Credit extended and cards issued by U... BALKANS STABILIZATION REGULATIONS Interpretations § 588.409 Credit extended and cards issued by U.S... not limited to, charge cards, debit cards, or other credit facilities issued by a U.S. financial...

31 CFR 542.409 - Credit extended and cards issued by U.S. financial institutions.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Credit extended and cards issued by U... SANCTIONS REGULATIONS Interpretations § 542.409 Credit extended and cards issued by U.S. financial..., charge cards, debit cards, or other credit facilities issued by a U.S. financial institution to a person...

Profit shifting and 'aggressive' tax planning by multinational firms: Issues and options for reform

OpenAIRE

Fuest, Clemens; Spengel, Christoph; Finke, Katharina; Heckemeyer, Jost; Nusser, Hannah

2013-01-01

This paper discusses the issue of profit shifting and ‘aggressive’ tax planning by multinational firms. The paper makes two contributions. Firstly, we provide some background information to the debate by giving a brief overview over existing empirical studies on profit shifting and by describing arrangements for IP-based profit shifting which are used by the companies currently accused of avoiding taxes. We then show that preventing this type of tax avoidance is, in principle, straightforward...

31 CFR 541.408 - Credit extended and cards issued by U.S. financial institutions.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Credit extended and cards issued by U... ZIMBABWE SANCTIONS REGULATIONS Interpretations § 541.408 Credit extended and cards issued by U.S. financial..., charge cards, debit cards, or other credit facilities issued by a U.S. financial institution to a person...

31 CFR 543.409 - Credit extended and cards issued by U.S. financial institutions.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Credit extended and cards issued by U...'IVOIRE SANCTIONS REGULATIONS Interpretations § 543.409 Credit extended and cards issued by U.S. financial..., charge cards, debit cards, or other credit facilities issued by a U.S. financial institution to a person...

Audit of Sandia Corporation`s pension plans and other prefunded benefits

Energy Technology Data Exchange (ETDEWEB)

1994-04-06

The audit disclosed that Sandia`s pension plans had $588.9 million in excess assets as of December 31, 1990, on a current value basis. If plan terminations and spin-offs occurred, at least $408.8 million of this amount could be returned to the Government without affecting the pension benefits that Sandia employees and retirees have earned. We recommended that Albuquerque take the necessary action to reduce the excess assets in the pension plans and recover the Government`s share. However, Albuquerque disagreed with the recommendation. Albuquerque justified leaving the excess assets in the pension plans to fund future plan amendments; to avoid future funding contributions; to avoid the costs and time-consuming administrative steps associated with taking action; and to prevent damaging effects on employee morale. We analyzed these points, and concluded that they should not prevent the Department from initiating action to return excess assets to the Government. Actuarial analysis of the pension plans showed that, even if certain plan adjustments were made, the plans were overfunded by $256 million as of December 31, 1991 (on an actuarial value basis).

WOMEN’S EMPOWERMENT AND FAMILY PLANNING: A REVIEW OF THE LITERATURE

Science.gov (United States)

PRATA, NDOLA; FRASER, ASHLEY; HUCHKO, MEGAN J.; GIPSON, JESSICA D.; WITHERS, MELLISSA; LEWIS, SHAYNA; CIARALDI, ERICA J.; UPADHYAY, USHMA D.

2017-01-01

Summary This paper reviews the literature examining the relationship between women’s empowerment and contraceptive use, unmet need for contraception and related family planning topics in developing countries. Searches were conducted using PubMed, Popline and Web of Science search engines in May 2013 to examine literature published between January 1990 and December 2012. Among the 46 articles included in the review, the majority were conducted in South Asia (n = 24). Household decision-making (n = 21) and mobility (n = 17) were the most commonly examined domains of women’s empowerment. Findings show that the relationship between empowerment and family planning is complex, with mixed positive and null associations. Consistently positive associations between empowerment and family planning outcomes were found for most family planning outcomes but those investigations represented fewer than two-fifths of the analyses. Current use of contraception was the most commonly studied family planning outcome, examined in more than half the analyses, but reviewed articles showed inconsistent findings. This review provides the first critical synthesis of the literature and assesses existing evidence between women’s empowerment and family planning use. PMID:28069078

Quality-assurance plan for water-resources activities of the U.S. Geological Survey in Idaho

Science.gov (United States)

Packard, F.A.

1996-01-01

To ensure continued confidence in its products, the Water Resources Division of the U.S. Geological Survey implemented a policy that all its scientific work be performed in accordance with a centrally managed quality-assurance program. This report establishes and documents a formal policy for current (1995) quality assurance within the Idaho District of the U.S. Geological Survey. Quality assurance is formalized by describing district organization and operational responsibilities, documenting the district quality-assurance policies, and describing district functions. The districts conducts its work through offices in Boise, Idaho Falls, Twin Falls, Sandpoint, and at the Idaho National Engineering Laboratory. Data-collection programs and interpretive studies are conducted by two operating units, and operational and technical assistance is provided by three support units: (1) Administrative Services advisors provide guidance on various personnel issues and budget functions, (2) computer and reports advisors provide guidance in their fields, and (3) discipline specialists provide technical advice and assistance to the district and to chiefs of various projects. The district's quality-assurance plan is based on an overall policy that provides a framework for defining the precision and accuracy of collected data. The plan is supported by a series of quality-assurance policy statements that describe responsibilities for specific operations in the district's program. The operations are program planning; project planning; project implementation; review and remediation; data collection; equipment calibration and maintenance; data processing and storage; data analysis, synthesis, and interpretation; report preparation and processing; and training. Activities of the district are systematically conducted under a hierarchy of supervision an management that is designed to ensure conformance with Water Resources Division goals quality assurance. The district quality

Zdroje institucionální důvěry v České republice

Czech Academy of Sciences Publication Activity Database

Čermák, Daniel; Stachová, Jana

2010-01-01

Roč. 46, č. 5 (2010), s. 683-717 ISSN 0038-0288 R&D Projects: GA MMR WD -13-07-1 Institutional research plan: CEZ:AV0Z70280505 Keywords : trust in institutions * political institutions * logistic regression Subject RIV: AO - Sociology, Demography Impact factor: 0.389, year: 2010

Integration of Environmental Planning Into the Army Master Planning Process

Science.gov (United States)

1992-10-01

the issues specific to the later assessment (ETL 1110-3-407, pp 1-9 to 1-10). Under the : estructured master planning process discussed in this report...Lisa~m 0111utHars M143 AMW PRO*b LAMM~e 0)3. AMW uaides, Uso ~ow (M Port RJ." 21719 7%s pubhicaton was repfodaaced on moycled V&Mp. /| / 121 DATEI:

202-S Hexone Facility supplemental information to the Hanford Facility Contingency Plan

International Nuclear Information System (INIS)

Ingle, S.J.

1996-03-01

This document is a unit-specific contingency plan for the 202-S Hexone Facility and is intended to be used as a supplement to the Hanford Facility Contingency Plan. This unit-specific plan is to be used to demonstrate compliance with the contingency plan requirements of WAC 173-303 for certain Resource Conservation and Recovery Act of 1976 (RCRA) waste management units. The 202-S Hexone Facility is not used to process radioactive or nonradioactive hazardous material. Radioactive, dangerous waste material is contained in two underground storage tanks, 276-S-141 and 276-S-142. These tanks do not present a significant hazard to adjacent facilities, personnel, or the environment. Currently, dangerous waste management activities are not being applied at the tanks. It is unlikely that any incidents presenting hazards to public health or the environment would occur at the 202-S Hexone Facility

Kenya's Climate Change Action Plan. Low Carbon Climate Resilient Development Pathway

Energy Technology Data Exchange (ETDEWEB)

Murphy, D.; Sawyer, D.; Stiebert, S.; McFatridge, S. [International Institute for Sustainable Development IISD, Winnipeg, Manitoba (Canada); Wuertenberger, L.; Van Tilburg, X.; Hekkenberg, M. [Energy research Centre of the Netherlands ECN, Policy Studies, Amsterdam (Netherlands); Owino, T.; Battye, W. [ClimateCare, Nairobi (Kenya); Mutia, T. [Regional Institute for Social Enterprise Kenya RISE, Nairobi (Kenya); Olum, P. [Climate Change Consultant (Kenya)

2012-12-15

Kenya Vision 2030 - the long-term development blueprint for the country - aims to transform Kenya into 'a newly industrialising, middle-income country providing a high quality of life to all its citizens in a clean and secure environment'. A low carbon climate resilient development pathway, as set out in this Climate Change Action Plan, can help meet Vision 2030 goals through actions that address both sustainable development and climate change. This pathway can also help the Government achieve the Millennium Development Goals and other internationally agreed development goals without compromising the environment and its natural resources. As Kenya realizes its development aspirations, there will be gains and risks. A growing population and economy with migration to cities will mean increases in greenhouse gas (GHG) emissions. Resulting environmental and social conditions, including increased competition over resources, could intensify vulnerability to climate risks. Transitioning to a low carbon climate resilient development pathway can address future risks thereby improving Kenya's ability to prosper under a changing climate while reducing the emissions intensity of a growing economy. Moving forward on the 2010 National Climate Change Response Strategy will help Kenya transition to a low carbon climate resilient development pathway that puts people and livelihoods at the forefront. The strategy recognized the importance of climate change and development, and this Climate Change Action Plan is the logical next step. A yearlong multistakeholder participatory process involving the public sector, private sector and civil society resulted in this Action Plan that identifies priority climate change actions for Kenya for the short, medium and long term. The Government of Kenya takes climate change and its impact on development seriously. Climate change is considered a crosscutting issue that will be mainstreamed in the planning process both at the national

Sub-Chandrasekhar-mass White Dwarf Detonations Revisited

Science.gov (United States)

Shen, Ken J.; Kasen, Daniel; Miles, Broxton J.; Townsley, Dean M.

2018-02-01

The detonation of a sub-Chandrasekhar-mass white dwarf (WD) has emerged as one of the most promising Type Ia supernova (SN Ia) progenitor scenarios. Recent studies have suggested that the rapid transfer of a very small amount of helium from one WD to another is sufficient to ignite a helium shell detonation that subsequently triggers a carbon core detonation, yielding a “dynamically driven double-degenerate double-detonation” SN Ia. Because the helium shell that surrounds the core explosion is so minimal, this scenario approaches the limiting case of a bare C/O WD detonation. Motivated by discrepancies in previous literature and by a recent need for detailed nucleosynthetic data, we revisit simulations of naked C/O WD detonations in this paper. We disagree to some extent with the nucleosynthetic results of previous work on sub-Chandrasekhar-mass bare C/O WD detonations; for example, we find that a median-brightness SN Ia is produced by the detonation of a 1.0 {M}ȯ WD instead of a more massive and rarer 1.1 {M}ȯ WD. The neutron-rich nucleosynthesis in our simulations agrees broadly with some observational constraints, although tensions remain with others. There are also discrepancies related to the velocities of the outer ejecta and light curve shapes, but overall our synthetic light curves and spectra are roughly consistent with observations. We are hopeful that future multidimensional simulations will resolve these issues and further bolster the dynamically driven double-degenerate double-detonation scenario’s potential to explain most SNe Ia.

Final disposal of spent nuclear fuel in Sweden. Some unresolved issues and challenges in the design and implementation of the forthcoming planning and EIA processes

International Nuclear Information System (INIS)

Bjarnadottir, H.; Hilding-Rydevik, T.

2001-06-01

The aim of the study is to highlight some unresolved and challenging issues in the forthcoming approximately six year long Environmental Impact Assessment (EIA) and planning process of the long-term disposal of spent nuclear fuel in Sweden. Different international and Nordic experiences of the processes for final disposal as well as from other development of similar scope, where experiences assumed to be of importance for final disposal of nuclear waste, have been described. Furthermore, issues relating to 'good EIA practice' as well as certain aspects of planning theory have also been presented. The current Swedish situation for the planning and EIA process of the final disposal of spent nuclear fuel was also been summarized. These different 'knowledge areas' have been compared and measured against our perception of the expectations towards the forthcoming process, put forward by different Swedish actors in the field. The result is a presentation of a number of questions and identification issues that the authors consider need special attention in the design and conduction of the planning and EIA process. The study has been realized through a literature survey and followed by reading and analysis of the written material. The main focus of the literature search was on material describing planning processes, actor perspectives and EIA. Material and literature on the technical and scientific aspects of spent nuclear fuel disposal was however deliberately avoided. There is a wealth of international and Swedish literature concerning final disposal of spent nuclear fuel - concerning both technical issues and issues concerning for example public participation and risk perception. But material of a more systematic and comparative nature (relating to both empirical and theoretical issues, and to practical experiences) in relation to EIA processes and communicative planning for final disposal of spent nuclear fuel seems to be more sparsely represented. Our perception of

Socioeconomic assessment: issues, status, and plans

International Nuclear Information System (INIS)

Boryczka, M.K.

1983-01-01

Numerous public meetings and hearings have been held in Texas, Mississippi, Louisiana and Utah on the issue of siting a nuclear waste repository in salt. Citizens in these potential site areas have raised many questions about how this facility will affect their quality of life. Questions about population and economic changes have been of particular concern. In developing a socioeconomic program, these issues and others have been an integral part of Battelle's socioeconomic studies. The three elements of Battelle's socioeconomic program are comprised of three elements: impact assessment, impact mitigation and community development, and impact monitoring. In addition, our approach to assessing socioeconomic impacts for the environmental assessment (EA) required by the Nuclear Waste Policy Act of 1982 are described. Since the EA analysis will address many of the issues raised in the site areas, these concerns will be elaborated on. Finally, various techniques for managing socioeconomic impacts will be presented. 6 references, 1 figure

Telecommunications network modelling, planning and design

CERN Document Server

Evans, Sharon

2003-01-01

Telecommunication Network Modelling, Planning and Design addresses sophisticated modelling techniques from the perspective of the communications industry and covers some of the major issues facing telecommunications network engineers and managers today. Topics covered include network planning for transmission systems, modelling of SDH transport network structures and telecommunications network design and performance modelling, as well as network costs and ROI modelling and QoS in 3G networks.

Fusion Canada issue 13

International Nuclear Information System (INIS)

1991-01-01

A short bulletin from the National Fusion Program. Included in this issue is a report on Canada's plans to participate in the Engineering Design Activities (EDA), bilateral meetings with Canada and the U.S., committee meeting with Canada-Europe, an update at Tokamak de Varennes on Plasma Biasing experiments and boronized graphite tests, fusion materials research at the University of Toronto using a dual beam accelerator and a review of the CFFTP and the CCFM. 2 figs

Enhanced Expression of WD Repeat-Containing Protein 35 via Nuclear Factor-Kappa B Activation in Bupivacaine-Treated Neuro2a Cells

Science.gov (United States)

Huang, Lei; Kondo, Fumio; Harato, Misako; Feng, Guo-Gang; Ishikawa, Naoshisa; Fujiwara, Yoshihiro; Okada, Shoshiro

2014-01-01

The family of WD repeat proteins comprises a large number of proteins and is involved in a wide variety of cellular processes such as signal transduction, cell growth, proliferation, and apoptosis. Bupivacaine is a sodium channel blocker administered for local infiltration, nerve block, epidural, and intrathecal anesthesia. Recently, we reported that bupivacaine induces reactive oxygen species (ROS) generation and p38 mitogen-activated protein kinase (MAPK) activation, resulting in an increase in the expression of WD repeat-containing protein 35 (WDR35) in mouse neuroblastoma Neuro2a cells. It has been shown that ROS activate MAPK through phosphorylation, followed by activation of nuclear factor-kappa B (NF-κB) and activator protein 1 (AP-1). The present study was undertaken to test whether NF-κB and c-Jun/AP-1 are involved in bupivacaine-induced WDR35 expression in Neuro2a cells. Bupivacaine activated both NF-κB and c-Jun in Neuro2a cells. APDC, an NF-κB inhibitor, attenuated the increase in NF-κB activity and WDR35 protein expression in bupivacaine-treated Neuro2a cells. GW9662, a selective peroxisome proliferator-activated receptor-γ antagonist, enhanced the increase in NF-κB activity and WDR35 protein expression in bupivacaine-treated Neuro2a cells. In contrast, c-Jun siRNA did not inhibit the bupivacaine-induced increase in WDR35 mRNA expression. These results indicate that bupivacaine induces the activation of transcription factors NF-κB and c-Jun/AP-1 in Neuro2a cells, while activation of NF-κB is involved in bupivacaine-induced increases in WDR35 expression. PMID:24466034

Navy Force Structure and Shipbuilding Plans: Background and Issues for Congress

Science.gov (United States)

2013-11-08

Issues for Congress Congressional Research Service 32 availabilit [ies], so that’s 34 [canceled surface ship maintenance availabilities]. We’ll cancel...to carry out the missions we may face in the future… we will need numbers, speed, and the ability to operate in shallow waters .” So as the Air-Sea

European Telecommunications Conference. Strategic Planning for the 1990s

Science.gov (United States)

Blackburn, J. F.

1990-06-01

The European Telecommunications Conference Strategic Planning for the 1990s provided information to delegates and their companies on strategic planning for the European market, particularly after the advent of the European Single Market at the end of 1992. The conference objective was to examine the impact of the initiatives of the European Commission (EC) and the changing attitudes to service provision by public and private sector organizations on industry and marketing. Organized by Blenheim Online and Logica, 40 delegates attended this conference, mainly from Europe, but with a few from the U.S. The papers were designed to illuminate such questions as emerging market sectors, impact of U.S telecommunications organizations in Europe, mergers and acquisition, standards, and value-added services.

World population growth, family planning, and American foreign policy.

Science.gov (United States)

Sharpless, J

1995-01-01

The US decision since the 1960s to link foreign policy with family planning and population control is noteworthy for its intention to change the demographic structure of foreign countries and the magnitude of the initiative. The current population ideologies are part of the legacy of 19th century views on science, morality, and political economy. Strong constraints were placed on US foreign policy since World War II, particularly due to presumptions about the role of developing countries in Cold War ideology. Domestic debates revolved around issues of feminism, birth control, abortion, and family political issues. Since the 1960s, environmental degradation and resource depletion were an added global dimension of US population issues. Between 1935 and 1958 birth control movements evolved from the ideologies of utopian socialists, Malthusians, women's rights activists, civil libertarians, and advocates of sexual freedom. There was a shift from acceptance of birth control to questions about the role of national government in supporting distribution of birth control. Immediately postwar the debates over birth control were outside political circles. The concept of family planning as a middle class family issue shifted the focus from freeing women from the burdens of housework to making women more efficient housewives. Family planning could not be taken as a national policy concern without justification as a major issue, a link to national security, belief in the success of intervention, and a justifiable means of inclusion in public policy. US government involvement began with agricultural education, technological assistance, and economic development that would satisfy the world's growing population. Cold War politics forced population growth as an issue to be considered within the realm of foreign policy and diplomacy. US government sponsored family planning was enthusiastic during 1967-74 but restrained during the 1980s. The 1990s has been an era of redefinition of

Policy planning for nuclear power: an overview of the main issues and requirements

International Nuclear Information System (INIS)

1995-05-01

The report contains information on the political, governmental, economic, financial and technical issues and requirements associated with planning and implementing a safe, economic and reliable nuclear power programme. It highlights the main areas in which policies must be developed and decisions taken, as well as the role and responsibilities of government, the plant owner and national industry. Also presented are the main criteria to assist policy planners in defining options and strategies which can achieve a balance among such objectives as cost effective and efficient electricity production, realistic and acceptable financing arrangements, national development requirements, safety and environmental protection. (NHA)

Micmac Strategic Energy Planning Initiative

Energy Technology Data Exchange (ETDEWEB)

Fred Corey

2007-02-02

In February 2005 the Aroostook Band of Micmacs submitted a grant application to the U.S. Department of Energy’s (DOE) Tribal First Steps Program. The purpose of the application was to request funding and technical assistance to identify and document Tribal energy issues, develop a Tribal energy vision, evaluate potential energy opportunities, and to develop an action plan for future Tribal energy activities. The grant application was subsequently funded by DOE, and the Aroostook Band of Micmacs hired an energy consultant to assist with completion of the project. In addition to identification and documentation of Tribal energy issues, and the development of a Tribal energy vision, the potential for wind energy development on Tribal land, and residential energy efficiency issues were thoroughly evaluated.

Housing Restitution and Privatisation: Both Catalysts and Obstacles to the Formation of Private Rental Housing in the Czech Republic and Estonia

Czech Academy of Sciences Publication Activity Database

Lux, Martin; Kährik, A.; Sunega, Petr

2012-01-01

Roč. 12, č. 2 (2012), s. 137-158 ISSN 1461-6718 R&D Projects: GA MMR WD-05-07-3 Institutional research plan: CEZ:AV0Z70280505 Keywords : Czech Republic * Estonia * housing tenure Subject RIV: AO - Sociology, Demography http://www.tandfonline.com/doi/abs/10.1080/14616718.2012.681574

Příčiny bezdomovství v ČR

Czech Academy of Sciences Publication Activity Database

Mikeszová, Martina

2011-01-01

Roč. 9, č. 5 (2011), s. 2-4 ISSN 1214-1720 R&D Projects: GA MMR WD-05-07-3 Institutional research plan: CEZ:AV0Z70280505 Keywords : homelessness * housing * poverty Subject RIV: AO - Sociology, Demography http://www.socioweb.cz/upl/editorial/download/190_SOCIOWEB_05_2011.pdf

Enhancing Student’s Understanding in Entrepreneurship Through Business Plan Simulation

OpenAIRE

Guzairy M.; Mohamad N.; Yunus A.R.

2018-01-01

Business Plan is an important document for entrepreneurs to guide them managing their business. Business Plan also assist the entrepreneur to strategies their business and manage future growth. That is why Malaysian government has foster all Higher Education Provider to set entrepreneurship education as compulsory course. One of the entrepreneurship education learning outcome is the student can write effective business plan. This study focused on enhancing student’s understanding in entrepren...

Transgenesis of the Wolffian duct visualizes dynamic behavior of cells undergoing tubulogenesis in vivo.

Science.gov (United States)

Atsuta, Yuji; Tadokoro, Ryosuke; Saito, Daisuke; Takahashi, Yoshiko

2013-05-01

Deciphering how the tubulogenesis is regulated is an essential but unsolved issue in developmental biology. Here, using Wolffian duct (WD) formation in chicken embryos, we have developed a novel method that enables gene manipulation during tubulogenesis in vivo. Exploiting that WD arises from a defined site located anteriorly in the embryo (pronephric region), we targeted this region with the enhanced green fluorescent protein (EGFP) gene by the in ovo electroporation technique. EGFP-positive signals were detected in a wide area of elongating WD, where transgenic cells formed an epithelial component in a mosaic manner. Time-lapse live imaging analyses further revealed dynamic behavior of cells during WD elongation: some cells possessed numerous filopodia, and others exhibited cellular tails that repeated elongation and retraction. The retraction of the tail was precisely regulated by Rho activity via actin dynamics. When electroporated with the C3 gene, encoding Rho inhibitor, WD cells failed to contract their tails, resulting in an aberrantly elongated process. We further combined with the Tol2 transposon-mediated gene transfer technique, and could trace EGFP-positive cells at later stages in the ureteric bud sprouting from WD. This is the first demonstration that exogenous gene(s) can directly be introduced into elongating tubular structures in living amniote embryos. This method has opened a way to investigate how a complex tubulogenesis proceeds in higher vertebrates. © 2013 The Authors Development, Growth & Differentiation © 2013 Japanese Society of Developmental Biologists.

Liquidity-related plan asset issues.

Science.gov (United States)

Murphy, B B; Johnson, M K; Zorn, W P

2000-12-01

By about 2025, most baby boomers will have retired, which will put a tremendous strain on public sector pension plans. Many will experience negative cash flows, and liquidity will be an increasing concern. Asset/liability studies can help measure the effect of this risk on system funding and contribution requirements, resulting in more informed asset allocation choices and benefit policies.

The transportation issue management system: A tool for issue resolution

International Nuclear Information System (INIS)

Branch, K.M.; Boryczka, M.K.

1987-01-01

During the last decade, issue management programs have been developed and used by a number of large corporations in the United States. These systems have generally been designed to help senior program managers identify issues, develop strategic plans, and resolve issues. These systems involve scanning and abstracting literature to create a database that is then used for 1) issue identification, 2) issue analysis, 3) priority assessment, 4) development of corporate position/strategic options, and 5) action planning and implementation. Most of the existing systems rely on staff to identify trends in the computerized output, analyze the importance of the issue to the company, and assist in developing corporate responses. The Department of Energy has recently developed an issue management system for the Office of Civilian Radioactive Waste Management's (OCRWM) transportation program. This system is designed to help DOE identify institutional issues related to radioactive waste transportation, analyze the issues, and resolve them in a manner that is responsive to interested parties. The system will contain pertinent information from DOE technical reports, other federal documents, correspondence, professional journals, popular literature, newsclips, legislation and testimony. The program is designed around a number of institutional issues including: prenotification, physical protection procedures; highway, rail, and barge routing; inspections and enforcement of shipments; emergency response; liability, cask design and testing; overweight trucks; rail service; modal mix; infrastructure improvements; training standards, and operational procedures

Final disposal of spent nuclear fuel in Sweden. Some unresolved issues and challenges in the design and implementation of the forthcoming planning and EIA processes

Energy Technology Data Exchange (ETDEWEB)

Bjarnadottir, H.; Hilding-Rydevik, T. [Nordregio, Stockholm (Sweden)

2001-06-01

The aim of the study is to highlight some unresolved and challenging issues in the forthcoming approximately six year long Environmental Impact Assessment (EIA) and planning process of the long-term disposal of spent nuclear fuel in Sweden. Different international and Nordic experiences of the processes for final disposal as well as from other development of similar scope, where experiences assumed to be of importance for final disposal of nuclear waste, have been described. Furthermore, issues relating to 'good EIA practice' as well as certain aspects of planning theory have also been presented. The current Swedish situation for the planning and EIA process of the final disposal of spent nuclear fuel was also been summarized. These different 'knowledge areas' have been compared and measured against our perception of the expectations towards the forthcoming process, put forward by different Swedish actors in the field. The result is a presentation of a number of questions and identification issues that the authors consider need special attention in the design and conduction of the planning and EIA process. The study has been realized through a literature survey and followed by reading and analysis of the written material. The main focus of the literature search was on material describing planning processes, actor perspectives and EIA. Material and literature on the technical and scientific aspects of spent nuclear fuel disposal was however deliberately avoided. There is a wealth of international and Swedish literature concerning final disposal of spent nuclear fuel - concerning both technical issues and issues concerning for example public participation and risk perception. But material of a more systematic and comparative nature (relating to both empirical and theoretical issues, and to practical experiences) in relation to EIA processes and communicative planning for final disposal of spent nuclear fuel seems to be more sparsely represented

The Creeping Irrelevance of U.S. Force Planning

National Research Council Canada - National Science Library

Record, Jeffrey

1998-01-01

... disintegration of established states. He believes U.S. force planning, for decades riveted on the prospect of massive conventional and even nuclear operations against a militarily-like adversary, now confronts a strategic environment heavily populated...

Safeguards and security issues at the MRS facility

International Nuclear Information System (INIS)

McGuinn, E.; Birch, M.; Jones, J.; Floyd, W.

1993-01-01

The U.S. Department of Energy's (DOE) Office of Civilian Radioactive Waste Management (OCRWM) is responsible for disposing of the nation's high level radioactive waste in a way that ensures the protection of the public from any unacceptable radiological risks and the maintenance of the national security. To achieve these objectives, OCRWM plans to institute a Nuclear Regulatory Commission (NRC)-approved security program at its facilities including the Monitored Retrievable Storage (MRS) facility. This program will safeguard nuclear information and provide not only for the physical protection of facilities but also for the nuclear material being handled and stored. Several key regulatory issues were identified during the development of the safeguards and security (S ampersand S) program for the MRS. These issues relate to developing a realistic definition of the security threat at the MRS and establishing a single set of regulatory requirements. Resolution of these issues is important to implement a realistic S ampersand S program who scope is commensurate with the potential risk at the MRS and complies with all appropriate regulatory requirements. OCRWM is working toward a timely resolution of these issues and on the formulation of an S ampersand S program for implementation at the MRS. As an initial step, DOE has proposed an S ampersand S strategy for the MRS based on a set of assumed resolutions to the key regulatory issues. With this approach, the facility designers will be able to evaluate possible S ampersand S concepts for integration into the MRS early in the design process

Technical issues related to NUREG 0800, Chapter 18: Human Factors Engineering/Standard Review Plan

International Nuclear Information System (INIS)

Savage, J.W.

1982-01-01

The revision of Chapter 18 of NUREG 0800, Human Factors Engineering Standard Review Plan (SRP) will be based on SECY 82-111 and guidance contained in NUREG 0700, NUREG 0801 and NUREG 0835, plus other references. In conducting field reviews of control rooms, the NRC has identified technical issues which can be used to enhance the development of the revised version of NUREG 0800, and to establish priorities among the list of possible Branch Technical Positions (BTP) in NUREG 0800, Rev. 0, Table 18.0-2. This report is a compilation of comments and suggestions from the people who used NUREG 0700 in the Control Room field reviews. This information was used to establish possible BTP topic priorities so that the most important BTPs could be issued first. The comments and suggestions are included for HFEB review in conjunction with the table of priorities

An overview of Ontario's 2013 long term energy plan

International Nuclear Information System (INIS)

Jobe, C.

2014-01-01

Ontario's 2013 Long Term Energy /Plan (LTEP) takes a pragmatic approach. The plan is designed to balance the following five principles namely: Cost effectiveness, Reliability, Clean energy, Community engagement, and Emphasis on conservation and demand management before building new generation. By taking a pragmatic and flexible approach and balancing these principles, Ontario's 2013 Long Term Energy Plan builds on the foundation laid by the 2010 LTEP while also lowering the projected total system costs. The key elements of the 2013 LTEP are described in this paper by highlighting the major features of these elements. (author)

COOLING WATER ISSUES AND OPPORTUNITIES AT U.S. NUCLEAR POWER PLANTS

Energy Technology Data Exchange (ETDEWEB)

Gary Vine

2010-12-01

This report has been prepared for the Department of Energy, Office of Nuclear Energy (DOE-NE), for the purpose of providing a status report on the challenges and opportunities facing the U.S. commercial nuclear energy industry in the area of plant cooling water supply. The report was prompted in part by recent Second Circuit and Supreme Court decisions regarding cooling water system designs at existing thermo-electric power generating facilities in the U.S. (primarily fossil and nuclear plants). At issue in the courts have been Environmental Protection Agency regulations that define what constitutes “Best Technology Available” for intake structures that withdraw cooling water that is used to transfer and reject heat from the plant’s steam turbine via cooling water systems, while minimizing environmental impacts on aquatic life in nearby water bodies used to supply that cooling water. The report was also prompted by a growing recognition that cooling water availability and societal use conflicts are emerging as strategic energy and environmental issues, and that research and development (R&D) solutions to emerging water shortage issues are needed. In particular, cooling water availability is an important consideration in siting decisions for new nuclear power plants, and is an under-acknowledged issue in evaluating the pros and cons of retrofitting cooling towers at existing nuclear plants. Because of the significant ongoing research on water issues already being performed by industry, the national laboratories and other entities, this report relies heavily on ongoing work. In particular, this report has relied on collaboration with the Electric Power Research Institute (EPRI), including its recent work in the area of EPA regulations governing intake structures in thermoelectric cooling water systems.

Marine Spatial Planning: Norway´s management plans

OpenAIRE

Hoel, Alf Håkon; Olsen, Erik

2010-01-01

Since the adoption of a government white paper on ocean governance in 2001, Norway has worked on the development and implementation of marine spatial planning in the format of regional management plans. Management plans for the Barents Sea and the oceans off northern Norway and the Norwegian Sea were adopted in 2006 and 2009, respect...

U.S. NRC's generic issues program

International Nuclear Information System (INIS)

Kauffman, J.V.; Foster, J.W.

2008-01-01

The United States Nuclear Regulatory Commission (NRC) has a Generic Issues Program (GIP) to address Generic Issues (GI). A GI is defined as 'a regulatory matter involving the design, construction, operation, or decommissioning of several, or a class of, NRC licensees or certificate holders that is not sufficiently addressed by existing rules, guidance, or programs'. This rather legalistic definition has several practical corollaries: First, a GI must involve safety. Second, the issue must involve at least two plants, or it would be a plant-specific issue rather than a GI. Third, the potential safety question must not be covered by existing regulations and guidance (compliance). Thus, the effect of a GI is to potentially change the body of regulations and associated guidance (e.g., regulatory guides). The GIP was started in 1976, thus it is a relatively mature program. Approximately 850 issues have been processed by the program to date. More importantly, even after 30 years, new GIs continue to be proposed. The entire set of Generic Issues (GIs) is updated annually in NUREG-0933, 'A Prioritization of Generic Safety Issues'. GIs normally involve complex questions of safety and regulation. Efficient and effective means of addressing these issues are very important for regulatory effectiveness. If an issue proves to pose a genuine, significant safety question, then swift, effective, enforceable, and cost-effective action needs to be taken. Conversely, if an issue is of little safety significance, the issue should be dismissed in an expeditious manner, avoiding unnecessary expenditure of resources and regulatory burden or uncertainty. This paper provides a summary of the 5-stage program, from identification through the regulatory assessment stage. The paper also includes a discussion of the program's seven criteria, sources of proposed GIs, recent improvements, publicly available information, historical performance, and status of current GIs. (authors)

Some recent human performance issues at U.S. nuclear plants

International Nuclear Information System (INIS)

Kauffman, John V.

1998-01-01

Some recent events at U.S. operating nuclear power plants revealed interesting human performance issues. Events discussed in this paper are: (1) a September 1996 event at Clinton, (2) a February 1997 event at Zion 1, and (3) March 1997 operator failures of 'in-house' examinations at LaSalle. The specific human performance weaknesses exhibited in these events, some underlying organizational or institutional issues and factors which influenced operators and their management, and implications regarding regulatory oversight are discussed. (author)

Bezdomovství v Praze a ve větších městech Středočeského kraje

Czech Academy of Sciences Publication Activity Database

Mikeszová, Martina

2010-01-01

Roč. 8, č. 5 (2010), s. 3-5 ISSN 1214-1720 R&D Projects: GA MMR WD-05-07-3 Institutional research plan: CEZ:AV0Z70280505 Keywords : housing * regions * homelessness Subject RIV: AO - Sociology, Demography http://www.socioweb.cz/upl/editorial/download/179_soc.web._05-2010%20final!.pdf

Women in Iraq: Background and Issues for U.S. Policy

National Research Council Canada - National Science Library

Pina, Aaron D

2006-01-01

The issue of women's rights in Iraq has taken on new relevance, following the U.S.-led invasion of Iraq in 2003, efforts to reconstruct Iraq, and recent elections for a Transitional National Assembly...

RING finger and WD repeat domain 3 (RFWD3) associates with replication protein A (RPA) and facilitates RPA-mediated DNA damage response.

Science.gov (United States)

Liu, Shangfeng; Chu, Jessica; Yucer, Nur; Leng, Mei; Wang, Shih-Ya; Chen, Benjamin P C; Hittelman, Walter N; Wang, Yi

2011-06-24

DNA damage response is crucial for maintaining genomic integrity and preventing cancer by coordinating the activation of checkpoints and the repair of damaged DNA. Central to DNA damage response are the two checkpoint kinases ATM and ATR that phosphorylate a wide range of substrates. RING finger and WD repeat domain 3 (RFWD3) was initially identified as a substrate of ATM/ATR from a proteomic screen. Subsequent studies showed that RFWD3 is an E3 ubiquitin ligase that ubiquitinates p53 in vitro and positively regulates p53 levels in response to DNA damage. We report here that RFWD3 associates with replication protein A (RPA), a single-stranded DNA-binding protein that plays essential roles in DNA replication, recombination, and repair. Binding of RPA to single-stranded DNA (ssDNA), which is generated by DNA damage and repair, is essential for the recruitment of DNA repair factors to damaged sites and the activation of checkpoint signaling. We show that RFWD3 is physically associated with RPA and rapidly localizes to sites of DNA damage in a RPA-dependent manner. In vitro experiments suggest that the C terminus of RFWD3, which encompass the coiled-coil domain and the WD40 domain, is necessary for binding to RPA. Furthermore, DNA damage-induced phosphorylation of RPA and RFWD3 is dependent upon each other. Consequently, loss of RFWD3 results in the persistent foci of DNA damage marker γH2AX and the repair protein Rad51 in damaged cells. These findings suggest that RFWD3 is recruited to sites of DNA damage and facilitates RPA-mediated DNA damage signaling and repair.

Concept and Method of Asset-Based Community Development Planning: A Case Study on Minlecun Community in Chongqing’s Yuzhong District

Institute of Scientific and Technical Information of China (English)

Huang; Ling; Liu; Yang; Xu; Jianfeng

2015-01-01

With the transformation of the Chinese economy from an extensive growth to intensive development, city development is also gradually turning from incremental construction to stock management. Community, as a basic unit of human settlements, is an important platform to build and improve the social governance capability. In 2013, Shiyoulu Jiedao Offi ce of Yuzhong District led the 1st urban community development planning, which was a milestone of Chongqing’s city regeneration and governance innovation. This paper focuses on two key issues: how to understand the community values and make the community development planning based on the above, and how to integrate with the local forces so that the community development planning can be integrated into the action plan. Combined with the practice of Minlecun Community Development Planning, using the concept of asset-based community development, a comprehensive survey is conducted on community assets(including three aspects of physical, human, and social capital), and a community comprehensive planning strategy is formulated which covers two parts: the optimization of community spaces and the upgrading of community governance. The paper explores the local-based community planning theories and methods from such aspects as value attitude, public participation, role transformation of urban planners, and others.

CITATION ANALYSIS OF URBAN PLANNING SCHOLARS IN THE U.S.

Directory of Open Access Journals (Sweden)

Sanchez Thomas W

2015-03-01

Full Text Available This article provides a complete citation analysis for the field of urban planning in the U.S. Urban planning is multi-disciplinary with a rich tradition of debate about the knowledge domain of both research and practice. Urban planning includes consideration of social, economic, technological, environmental, and political systems that are highly sophisticated, which therefore has an extensive body of scholarship. The article argues that Google Scholar is an appropriate source of citation data for urban planning and includes a brief example of one urban planning scholar to demonstrate GS citation patterns. This is followed by the results of a descriptive analysis showing general patterns of citation activity for urban planning schools. A greater depth of analysis is required to better understand the dynamics of these scholarly activities.

222-S laboratory quality assurance plan

International Nuclear Information System (INIS)

Meznarich, H.K.

1995-01-01

This document provides quality assurance guidelines and quality control requirements for analytical services. This document is designed on the basis of Hanford Analytical Services Quality Assurance Plan (HASQAP) technical guidelines and is used for governing 222-S and 222-SA analytical and quality control activities. The 222-S Laboratory provides analytical services to various clients including, but not limited to, waste characterization for the Tank Waste Remediation Systems (TWRS), waste characterization for regulatory waste treatment, storage, and disposal (TSD), regulatory compliance samples, radiation screening, process samples, and TPA samples. A graded approach is applied on the level of sample custody, QC, data verification, and data reporting to meet the specific needs of the client

U.S. national issues on environmental hydrology and hydrogeology - Local and emerging global perspectives

International Nuclear Information System (INIS)

Sharp, J.M. Jr.

1991-01-01

In the US, hydrologic considerations have risen to the forefront of a number of important national issues. These issues focus on aspects of water availability and quality, but also impact other environmental, economic, and social situations. Surface-water resources in the US are essentially allocated and new socioenvironmental concerns may limit further surface-water exploitation. Ground-water use is increasing, but availability is not uniform. Some areas suffer from ground-water depletion and associated social and economic hardships. The quality of US coastal waters, rivers, lakes, and ground-water resources has seriously deteriorated in the last fifty years. Pollution is ubiquitous; vast sums of money have been spent in attempts at remediation. New methods for the disposal of sewage, industrial wastes, and nuclear wastes and for water treatment must be developed. Furthermore, the widespread agricultural contamination of ground water is just now being documented. This is leading to development of well-head protection criteria, a small but important venture into land-use planning. It is in comprehensive land-use planning that hydrology and hydrogeology should be of greatest value. The loss of prime agricultural lands and wildlife habitat as well as localized problems, such as flooding, subsidence, and pollution of water resources are problems which require vigorous emerging global issues will place great reliance on hydrologists and hydrogeologists of the future. Potential climate changes may alter our water resources base; population growth and third-world development will stress global water resources; aerosols are polluting water resources; and pollution does not stop at national boundaries. How to solve these newly emerging global problems is also an important US national issue

An audit of local government planning tools for their potential use in addressing community food and nutrition issues.

Science.gov (United States)

Good, Elizabeth; Hammond, Melinda; Martin, Caroline; Burns, Catherine; Groos, Anita

2010-04-01

This project aimed to identify how local government planning tools could be used to influence physical and policy environments to support healthy eating behaviours in communities. An audit of Queensland's legislative and non-legislative local government planning tools was conducted by a public health nutritionist to assess their potential use in addressing strategies to achieve positive nutrition outcomes. Ten strategies were identified and covered the following themes: improving access to healthy foods and drinks; increasing access to breastfeeding facilities; decreasing fast food outlet density; and unhealthy food advertising. The audit found that all of the 10 strategies to achieve positive nutrition outcomes could be considered through three or more of the planning tools. Based on the findings of this audit, local government planning tools provide opportunities to address food and nutrition issues and contribute toward creating physical and policy environments that support healthy eating behaviours.

How public issues shape environmental restoration plans - experiences with Colorado UMTRA projects

International Nuclear Information System (INIS)

Hunt, B.; Monaghan, J.

1991-01-01

Federal environmental restoration plans are being significantly impacted by open-quotes grassrootsclose quotes public pressure and by community demands, some of which have little relation to the technical standards of remediation and which go well beyond authorizing legislation. These demands often represent significant additional project costs. A review of Uranium Mill Tailings Remedial Action (UMTRA) Program experiences in Colorado suggests that the more serious open-quotes grassrootsclose quotes issues associated with remediation rarely diminish and, in fact, will intensify over time. This presents program administrators with the dilemma of attempting to adhere to program mandates and keep projects within budget, while at the same time trying to be responsive to community concerns. Such high-profiled community debates have the ability to delay remediation and even jeopardize important projects. After prolonged public debate, when it becomes clear an issue will not dissipate, project officials may be forced to meet certain community demands. Often, this results in not only increased costs, but a loss of public confidence in clean-up efforts. Evidence also suggests, however, that when critical public issues can be identified and addressed before they become overly contentious, significant problems and controversy can be avoided; but, the situation is made difficult because project officials often lack the policy guidance to determine which, if any, community demands should be addressed and to what extent they should be met. The adoption of several key public policy principles by program administrators will provide a greater ability to address community demands in a timely and successful manner

The Waste Management Plan integration into Decommissioning Plan of the WWR-S research reactor from Romania

International Nuclear Information System (INIS)

Barariu, Gheorghe; Oprescu, Theodor; Filip, Mihaela; Sociu, Florin

2008-01-01

The paper presents the progress of the Radioactive Waste Management Plan which accompanies the Decommissioning Plan for research reactor WWR-S located in Magurele, Ilfov, near Bucharest, Romania. The new variant of the Decommissioning Plan was elaborated taking into account the IAEA recommendation concerning radioactive waste management. A new feasibility study for WWR-S decommissioning was also developed. The preferred safe management strategy for radioactive wastes produced by reactor decommissioning is outlined. The strategy must account for reactor decommissioning, as well as rehabilitation of the existing Radioactive Waste Treatment Plant and the upgrade of the Radioactive Waste Disposal Facility at Baita-Bihor. Furthermore, the final rehabilitation of the laboratories and reusing of cleaned reactor building is envisaged. An inventory of each type of radioactive waste is presented. The proposed waste management strategy is selected in accordance with the IAEA assistance. Environmental concerns are part of the radioactive waste management strategy. (authors)

Effects of Manufacturing Firm’s Capacity Planning on Performance of the Firm

Directory of Open Access Journals (Sweden)

Kifordu Anthony

2017-12-01

Full Text Available This study investigated capacity planning and performance in the manufacturing sector in the Southeastern States of Nigeria based on selected Brewing industries. The population of the study was 740 staff of the brewing industry in South-Eastearn Nigeria. The sample size of 509 was obtained using a Taro Yamani’s statistical formula. The study used questionnaire and oral interview guide for data gathering. A test- retest stood completed using Spearman’s rank correlation, giving a coefficient of 0.9. Findings revealed that capacity planning significantly enriched economic performance of the industry studied. There existed a strong affirmative relationship among capacity necessities planning and resources requirements planning. The paper suggested use of capacity planning as a technique to improve all performance factors. Similarly, performance advantage subsist from the correlation of volume requirements plans and resources requirements planning. The paper summarily held the position that volume preparation improved the economic performance in the industry under review. This inferred that goals achievement is possible. Likewise, the finding of substantial constructive association between volume supplies planning and resources supplies planning inferred an affirmative communication between the variables. This meant that resources supplies planning which was a method of organizing the detailed production plans could lead to an improvement of capacity supplies planning. That is to say, they are taking future decisions on the substances required for production capability of the brewing facility.

Renewing U.S. mathematics: A plan for the 1990s

Energy Technology Data Exchange (ETDEWEB)

NONE

1990-12-31

In 1981 a committee of the National Research Council was formed to investigate the health of the mathematical sciences in the US. Its 1984 report, Renewing US Mathematics: Critical Resource for the future found that although the field was thriving intellectually, government support had deteriorated to a dangerously low level. Moreover, the number of young people entering the mathematical sciences had decreased to a level inadequate to replenish the field. The 1984 Report recommended a plan for renewal, the National Plan for Graduate and Postdoctoral Education in the Mathematical Sciences. That plan`s essential feature was a call for funding to bring support for the mathematical sciences into balance with support for the physical sciences and engineering. The interdisciplinary committee that wrote the 1984 Report quickly realized that the low level of research support for US mathematical sciences was so severe that it threatened the vitality of the entire scientific enterprise. As requested by the National Science Foundation (NSF) and the Interagency Committee for Extramural Mathematics Programs (ICEMAP), this report updates the 1984 Report. Specifically, the charge directed the committee to (1) update that report, describing the infrastructure and support for US mathematical sciences research; (2) assess trends and progress over the intervening five years against the recommendations of the 1984 Report; (3) briefly assess the field scientifically and identify significant opportunities for research, including cross-disciplinary collaboration; and (4) make appropriate recommendations designed to ensure that US mathematical sciences research will meet national needs in coming years.

Moderní nástroje sociálního bydlení pro mladé rodiny jako nepřímá podpora růstu porodnosti

Czech Academy of Sciences Publication Activity Database

Lux, Martin

2010-01-01

Roč. 8, č. 5 (2010), s. 1-3 ISSN 1214-1720 R&D Projects: GA MMR WD-05-07-3 Institutional research plan: CEZ:AV0Z70280505 Keywords : housing * housing affordability * regional differences Subject RIV: AO - Sociology, Demography http://www.socioweb.cz/upl/editorial/download/179_soc.web._05-2010%20final!.pdf

Enhancing Student’s Understanding in Entrepreneurship Through Business Plan Simulation

Directory of Open Access Journals (Sweden)

Guzairy M.

2018-01-01

Full Text Available Business Plan is an important document for entrepreneurs to guide them managing their business. Business Plan also assist the entrepreneur to strategies their business and manage future growth. That is why Malaysian government has foster all Higher Education Provider to set entrepreneurship education as compulsory course. One of the entrepreneurship education learning outcome is the student can write effective business plan. This study focused on enhancing student’s understanding in entrepreneurship through business plan simulation. This study also considers which of the factor that most facilitate the business simulation that help the student to prepare effective business plan. The methodology of this study using quantitative approach with pre-and post-research design. 114 students take part as respondent in the business simulation and answer quantitative survey pre-question and post question. The crucial findings of this study are student characteristic factor after playing the simulation contribute much on facilitate business plan learning. The result has shown that the business plan simulation can enhance undergraduate student in understanding entrepreneurship by preparing effective business plan before opening new startup.

Ecodriver. D2.1: Dissemination and Communication plan_Issue2 (Incl. D2.2: Project Website)

NARCIS (Netherlands)

Winder, A.; Coppola, C.

2014-01-01

The Dissemination and Communication Plan sets the reference for all planned dissemination activities during the project lifetime. It defines target groups, communication actions, how they will be performed, by whom and when, as well as the project’s identity. This report also incorporates an outline

Experimental investigations on the fluid flow through an asymmetric rod bundle (P/D = 1.148, W/D = 1.045)

International Nuclear Information System (INIS)

Rehme, K.

1983-11-01

Measurements of the distributions of the mean velocity, the wall shear stresses and the turbulence were performed in a wall subchannel of a rod bundle of four parallel rods arranged asymmetrically in a rectangular channel (P/D = 1.148, W/D = 1.045). The Reynolds number of this investigations was Re = 5.88 x 10 4 . The experimental results show that the momentum transport is highly anisotropic especially in the gaps of the rod bundle. Influences of secondary flow cannot be detected in the distribution of the time-mean velocity. The comparison between experimental wall shear stress distributions and those calculated with the VELASCO-code shows discrepancies both in the gap between the rod and channel walls and in the gap between the rods caused by the high momentum transport between the two subchannels. (orig.) [de

U.S.-Vietnam Relations in 2010: Current Issues and Implications for U.S. Policy

Science.gov (United States)

2010-08-06

with Aluminum Corp. of China Ltd to mine bauxite in Vietnam’s Central Highlands.68 The venture appears to be part of a larger Vietnamese government...increasing its economic influence over and within Vietnam, as shown by the criticisms that followed the spring 2009 announcement of a bauxite mining joint...27 Controversial Bauxite Plan for Central Highlands.......................................................... 28 Political

Editor’s Note Vol. 2 Issue 1

Directory of Open Access Journals (Sweden)

Elisa Boff

2013-03-01

Full Text Available The International Journal of Interactive Multimedia and Artificial Intelligence provides an interdisciplinary forum in which scientists and professionals can share their research results and report new advances on Artificial Intelligence and Interactive Multimedia techniques.This special issue “Artificial Intelligence and Social Application” includes extended versions of selected papers from Artificial Intelligence and Education area of the 13th edition of the Ibero-American Conference on Artificial Intelligence, held in Cartagena de Indias - Colombia, November, 2012. The issue includes, thus, five selected papers, describing innovative research work, on Artificial Intelligence in Education area including, among others: Recommender Systems, Learning Objects, Intelligent Tutoring Systems, Multi-Agent Systems, Virtual Learning Environments, Case-based reasoning and Classifiers Algorithms. This issue also includes six papers in the Interactive Multimedia and Artificial Intelligence areas, dealing with subjects such as User Experience, E-Learning, Communication Tools, Multi-Agent Systems, Grid Computing. IBERAMIA 2012 was the 13th edition of the Ibero-American Conference on Artificial Intelligence, a leading symposium where the Ibero-American AI community comes together to share research results and experiences with researchers in Artificial Intelligence from all over the world. The papers were organized in topical sections on knowledge representation and reasoning, information and knowledge processing, knowledge discovery and data mining, machine learning, bio-inspired computing, fuzzy systems, modelling and simulation, ambient intelligence, multi-agent systems, human-computer interaction, natural language processing, computer vision and robotics, planning and scheduling, AI in education, and knowledge engineering and applications.The Ibero-American Society of Artificial Intelligence (IBERAMIA is a legally-constituted non-profit association

EUROPEAN INTEGRATION FROM POLAND’S VIEWPOINT. SELECTED ISSUES

OpenAIRE

Iwona M. Pawlas

2014-01-01

It has been ten years since Poland joined the European Union in May 2004. Integration with the EU structures resulted in considerable economic, social and political advantages. On the other hand membership in the EU created new challenges for Poland, the Polish companies and the Polish citizens. The paper reviews selected issues of Poland’s integration with the European Union with special focus on net financial effect of membership, competitiveness of Polish goods on single European market, p...

Proposals for enhancing tactical planning in grocery retailing with S&OP

DEFF Research Database (Denmark)

Dreyer, Heidi Carin; Kiil, Kasper; Dukovska-Popovska, Iskra

2018-01-01

Purpose-The purpose of this paper is to explore tactical planning in grocery retailing and propose how process and integration mechanisms from sales and operations planning (S&OP) can enhance retail tactical planning.Design/methodology/approach-This work follows an explorative design with case...... studies from the grocery retailing industry in Finland, Norway, and the UK.Findings-The tactical planning process focuses on demand management and securing product availability from suppliers in order to reach sales targets. Less attention is directed toward balancing supply and demand or toward providing...... a single plan to guide company operations. Planning appeared to be functionally oriented with limited coordination between functional plans, but it did include external integration that improved forecast accuracy.Research limitations/implications-The study involves grocery retailer cases with variable...

Planning Curriculum in International Education.

Science.gov (United States)

Durtka, Sharon; Dye, Alex; Freund, Judy; Harris, Jay; Kline, Julie; LeBreck, Carol; Reimbold, Rebecca; Tabachnick, Robert; Tantala, Renee; Wagler, Mark

International education begins at home, in the very communities and environments most familiar to students. A student does not need to travel outside U.S. borders to meet the peoples or understand the issues of the global village. This planning guide shows how curriculum in all subject areas encompasses global challenges, global cultures, and…

The Blayais major construction project into perspective: nuclear power and land use planning in France, from the 1960's to the 1990's

International Nuclear Information System (INIS)

Cardarelly, Sebastien

2014-01-01

The energy issue has heavily influenced the regional planning of the French territory. As a massive public investment endeavour, the nuclear power program propelled the development of an important industry and rose the question of its incorporation into regional planning policies. This article focuses on the 'Grand Chantier' of the Blayais power station

Concentrating Solar Power and Water Issues in the U.S. Southwest

Energy Technology Data Exchange (ETDEWEB)

Bracken, Nathan [Western States Water Council, Murray, UT (United States); Macknick, Jordan [National Renewable Energy Lab. (NREL), Golden, CO (United States); Tovar-Hastings, Angelica [National Renewable Energy Lab. (NREL), Golden, CO (United States); Komor, Paul [Univ. of Colorado, Boulder, CO (United States); Gerritsen, Margot [Stanford Univ., CA (United States); Mehta, Shweta [Stanford Univ., CA (United States)

2015-03-01

Concentrating solar power (CSP) systems utilize the sun's energy to create heat that is used to generate electrical power. CSP systems in the United States are installed primarily in the Southwest, with 92% of plants that are operational, under construction, or under development located in three western states--Arizona, California, and Nevada. This report provides an overview of CSP development in these states, or the 'Southwest' for the purposes of this discussion, with a particular focus on the water supply issues associated with CSP. The Western Governors' Association (WGA) commissioned staff from the Western States Water Council (WSWC) to collaborate with staff from the National Renewable Energy Laboratory (NREL) to prepare this report. The WGA has long supported the effective management of the West's water resources, as well as the development of a clean, diverse, reliable, and affordable energy supply consisting of traditional and renewable energy resources. This report is specifically intended to help inform these goals, especially as WGA continues to underwrite a Regional Transmission Expansion Planning project, undertaken by the WSWC and the Western Electricity Coordinating Council (WECC), to better understand energy development within the existing and future water resource constraints of the West. This report builds upon earlier research conducted by NREL, the University of Colorado-Boulder, and Stanford University that was supported through the Joint Institute for Strategic Energy Analysis (JISEA) and presents information gathered through extensive research and literature reviews, as well as interviews and outreach with state water administrators and energy regulators, WECC and other experts familiar with CSP development in the Southwest.

Financial Planning and Financial Instruments: 2013 in Review, 2014 in Prospect

OpenAIRE

Mark Brimble; Ciorstan Smark

2013-01-01

The Global Financial Crisis (GFC); changes in regulation; issues in public perception and trust have contributed to a troubled 2013 for financial planners. As financial planning and wealth management providers seek to bolster their professional status, the Financial Planning Education Council’s National Curriculum and Accreditation Framework and ASIC’s minimum training requirements are also a space to watch. In prospect, 2014 will offer opportunities and challenges in the form of ...

Planning and managing a corporate event : case: Event Activation Galaxy Studio Samsung S7/ S7 Edge

OpenAIRE

Bui, Quyen; Tran, Fa

2017-01-01

The thesis was written about the case: Event Activation Studio Galaxy Samsung S7/S7 Edge. Samsung is a global leading conglomerate company in the technology industry. This thesis discusses how to plan and manage an Event Activation for Samsung. The primary objective of this thesis was to provide a step-by-step guideline for planning and managing a corporate event. This objective was achieved by performing the following tasks: clarifying the influential role of corporate events in marketi...

31 CFR 594.410 - Credit extended and cards issued by U.S. financial institutions.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Credit extended and cards issued by U... TERRORISM SANCTIONS REGULATIONS Interpretations § 594.410 Credit extended and cards issued by U.S. financial... agreements, including, but not limited to, charge cards, debit cards, or other credit facilities issued by a...

Energy planning and investment for increased earnings: the case of Nigeria's oil and gas resources

Energy Technology Data Exchange (ETDEWEB)

Ojo, A.T.

1984-03-01

In view of Nigeria's limited reserves of oil and the high growth rate of oil consumption, and in the wake of the developments in the world oil market since 1981 which have resulted in a drastic shortfall in Nigeria's revenues, the main objective of this article is to highlight some important issues that would spur policy makers towards improved energy planning and increased energy investment in Nigeria so as to assist her in the rationalization of the energy production-mix and consumption, as well as in earning increased revenues from her oil and gas resources. Policymakers in Nigeria are called upon to put an end to further procrastination concerning the liquefied natural gas (LNG) investment project so that the bulk of the country's gas, which is presently being flared, can be re-injected, consumed locally, and exported to supplement dwindling oil revenues. 23 notes and references, 3 tables.

Year 2000 commercial issues

International Nuclear Information System (INIS)

Kratz, M.P.J.; Booth, R.T.

1998-01-01

This presentation focused on commercial aspects of the Y2K including: (1) special communication issues, (2) outsourcing transactions, (3) joint ventures and the significance for the oil and gas industry, and (4) contingency planning. Communication issues involve interaction with suppliers and vendors of critical systems, liability for Y2K communications (misrepresentation, defamation, promissory estoppel, statutory liability), securities disclosure (Canadian and US SEC requirements), protected communications, protection for Year 2000 statements. Outsourcing problems highlighted include resistance of suppliers to assume responsibility for Y2K problem remediation, factors which support and negate supplier responsibility, scope of suppliers' obligation, and warranties in respect of third party software. Regarding joint ventures, questions concerning limitations on liability, supply warranties, stand-by arrangements, stockpiling inventory, indemnities, confidentiality, operator compensation versus operator risk, and insurance were raised and addressed. Among contingency planning issues the questions of Y2K legal audit, and disclosure aspects of contingency planning were the featured concerns. figs

Year 2000 commercial issues

Energy Technology Data Exchange (ETDEWEB)

Kratz, M.P.J.; Booth, R.T. [Bennett Jones, Calgary, AB (Canada)

1998-12-31

This presentation focused on commercial aspects of the Y2K including: (1) special communication issues, (2) outsourcing transactions, (3) joint ventures and the significance for the oil and gas industry, and (4) contingency planning. Communication issues involve interaction with suppliers and vendors of critical systems, liability for Y2K communications (misrepresentation, defamation, promissory estoppel, statutory liability), securities disclosure (Canadian and US SEC requirements), protected communications, protection for Year 2000 statements. Outsourcing problems highlighted include resistance of suppliers to assume responsibility for Y2K problem remediation, factors which support and negate supplier responsibility, scope of suppliers` obligation, and warranties in respect of third party software. Regarding joint ventures, questions concerning limitations on liability, supply warranties, stand-by arrangements, stockpiling inventory, indemnities, confidentiality, operator compensation versus operator risk, and insurance were raised and addressed. Among contingency planning issues the questions of Y2K legal audit, and disclosure aspects of contingency planning were the featured concerns. figs.

Sustainable food planning: evolving theory and practice

NARCIS (Netherlands)

Viljoen, A.; Wiskerke, J.S.C.

2012-01-01

Half the world’s population is now urbanised and cities are assuming a larger role in debates about the security and sustainability of the global food system. Hence, planning for sustainable food production and consumption is becoming an increasingly important issue for planners, policymakers,

Analyzing an Integrated Planning Approach Among Planning Scale and Sector A Case Study of Malang City’s Vision as The City of Education

Directory of Open Access Journals (Sweden)

Akhmad Amirudin

2014-04-01

Full Text Available Integrated planning is more needed by government today because of the complexity of problems and limited resources. Integrated planning can undertake the problems by giving comprehensive solution and provide how much resources are needed to reach the goal. Integrated planning approach is implied to provide better tools to guide actions towards the development of cities, improvement of human conditions, and ultimately a better urbanism. So the research focused on integrated planning in Malang City based on Malang City’s vision, strategic planning, operational planning, budgeting planning in Malang City to achieve Malang City’s vision as the city of Education. In this study, researcher used qualitative method with descriptive research, which is a research process aims to describe the exact nature / something happened and took place on the research conducted. The research purpose is to identify and describe and analyze the process of Malang City Planning Agency integrate other planning scale and sector in developing planning; and to identify, describe and analyze the process of Malang City Planning Agency integrated all stakeholders in Integrated Planning process. This research use descriptive research method. The reason to use descriptive research method in this study because the principle objectives of this study aimed to describe, illustrate in a systematic, factual and accurate statement of the facts and the relationship between phenomenon. Then qualitative method was directed at the individual's background and a holistic (whole. So in this case should not isolate the individual or organization into a variable or hypothesis, but should view it as part of wholeness. The result of this research in the case study of Malang City has shown thatThe case study of Malang City showed that various sectors recognized but did not pay much attention to Malang City’s vision as City of Education in their plans; however, Regional Mid-term Development

Slavic issue and Russian nationalism in liberal journalism in 1860s

Directory of Open Access Journals (Sweden)

Екатерина Юрьевна Федорова

2013-12-01

Full Text Available The article is devoted to the problems of the nationalism perception in the liberal journalism in the 1860s. The author reveals the political and ideological factors which prompted liberalism theorists K.D. Kavelin, B.N. Chicherin, A.D. Gradovsky to consider national issues. There are analyzed the common and particular features in the works of publicists of public school. Special attention is paid to their attitude to the Slavic idea, the Polish issue and the Russian nationalism.

Banner plans to issue new bonds to cover university of Arizona medical center purchase

Directory of Open Access Journals (Sweden)

Robbns RA

2015-10-01

Full Text Available No abstract available. Article truncated at 150 words. Modern Healthcare is reporting that Banner Health is issuing new bonds this week to refinance older debt (1. Banner financed the $1 billion purchase of the University of Arizona Health Network (UAHN including the University of Arizona Medical Center with a $700 million short-term loan from investment bank Mizuho in February. Banner is issuing $100 million in tax-exempt, fixed rate Series 2015A bonds. It is also planning to take on an additional $500 million in taxable and tax-exempt debt that will be used to replace the short-term loans associated with the purchase. Banner is focusing on how to improve the return on its UAHN investment, which has dragged down its earnings. UAHN's financial performance has deteriorated with an operating margin declining to -4.3% in fiscal 2014, down from -1.2% the previous fiscal year. Before that, UAHN was profitable, according to Banner Chief Financial Officer Dennis Dahlen. Banner reported an operating ...

Studi Faktor-faktor Pemotivasi Manajemen Melakukan Tax Planning

OpenAIRE

Indrawati Indrawati; Gideon Setyo Budiwitaksono

2015-01-01

The purpose of this study is to examine the influence of Tax Policy, Tax Law, and Tax Administration on Tax Planning. Our samples consist of 20 Tax Cosultant’s Clients in Surabaya.The Results of this study show that tax policy and tax administration is not a factor that can motivate management to perform tax planning. While the tax laws is a factor that can motivate management to perform tax planning. This research suggests to the Government to issue tax regulations clearly and unambigu...

Prioritization of generic safety issues

International Nuclear Information System (INIS)

Emrit, R.; Minners, W.; VanderMolen, H.

1983-12-01

This report presents the priority rankings for generic safety issues related to nuclear power plants. The purpose of these rankings is to assist in the timely and efficient allocation of NRC resources for the resolution of those safety issues that have a significant potential for reducing risk. The report focuses on the prioritization of generic safety issues. Issues primarily concerned with the licensing process or environmental protection and not directly related to safety have been excluded from prioritization. The prioritized issues include: TMI Action Plan items under development; previously proposed issues covered by Task Action Plans, except issues designated at Unresolved Safety Issues (USIs) which had already been assigned high priority; and newly-proposed issues. Future supplements to this report will include the prioritization of additional issues. The safety priority rankings are HIGH, MEDIUM, LOW, and DROP and have been assigned on the basis of risk significance estimates, the ratio of risk to costs and other impacts estimated to result if resolutions of the safety issues were implemented, and the consideration of uncertainties and other quantitative or qualitative factors. To the extent practical, estimates are quantitative

Experimental investigations on the fluid flow through an asymmetric rod bundle (P/D = 1.148, W/D = 1.074)

International Nuclear Information System (INIS)

Rehme, K.

1984-12-01

Measurements of the distributions of the mean velocity, the wall shear stresses and the turbulence were performed in a wall subchannel of a rod bundle of four prallel rods arranged asymmetrically in a rectangular (P/D = 1.148, W/D = 1.074). The Reynolds number of this investigations was Re = 7.89 x 10 4 . The results obtained by a fully automated rig are compared with those from manual operation. The experimental results show that the momentum transport is highly anisotropyc especially in the gaps of the rod bundle. Influences of secondary flow cannot be detected in the distribution of the time-mean velocity. The comparison between experimental wall shear stress distributions and those calculated with the VELASCO-code shows discrepancies both in the gap between the rod and channel walls and in the gap between the rods caused by the high momentum transport between the two subchannels. (orig.) [de

High attributable risk due to arsenic for lung cancer in Yunnan tin mine reported by WD Hazelton et al

International Nuclear Information System (INIS)

Sun Shiquan

2004-01-01

Using two-stage clonal expansion model with data-base provided by Lubin, WD Hazelton et al indicated the high risk of arsenic, but not radon, in the etiology of Yunnan tin miner's lung cancer. The author of this review iterated the problems in the data-base of Lubin, and considered that it may result in low estimate for the risk of radon in paper of Hazelton et al. Attributable risk was estimated by them with changing exposure patterns of each individual ,but the efficacy of this two-stage model will be violated by the invariability of appointed radon/arsenic exposures. Risk comparison was used to distinguish the contribution from radon/arsenic, which was hampered by the high correlation between their joint exposures. As Lubin, Hazelton et al neglected the confounding from environmental arsenic pollution in early years. From all of above, their viewpoint is worth to be deliberated

Ethical issues in measuring biomarkers in children´s environmental health

Czech Academy of Sciences Publication Activity Database

Sly, P. D.; Eskenazi, B.; Pronczuk, J.; Šrám, Radim; Diaz-Barriga, F.; Machin, D. G.; Carpenter, D. O.; Surdu, S.; Meslin, E. M.

2009-01-01

Roč. 117, č. 8 (2009), s. 1185-1190 ISSN 0091-6765 Institutional research plan: CEZ:AV0Z50390512 Keywords : biobanks * biomarkers * children Subject RIV: DN - Health Impact of the Environment Quality Impact factor: 6.191, year: 2009

HUMAN-MACHINE INTERACTION IN SOLVING TASKS OF THE PLANNING DEPARTMENT

Directory of Open Access Journals (Sweden)

Boris Alekseyevich Kucherov

2017-12-01

Full Text Available The paper discusses issues of human-machine interaction in solving tasks of the planning department under severe resource restrictions using information technology. The negative factors influencing specialists of the planning department in solving their tasks under the given circumstances are shown. Specific features of designing the user interface in this subject area are noted. Directions to increase the efficiency of reaction of the planning department’s specialists to change the current situation by visual and sound notification of various events are marked. Various ways to develop user interface to generate a conflict-free plan under severe resource restrictions are considered. The variants of informative presentation of operational and statistical information to stakeholders are analyzed. These issues are discussed by the example of the planning department which solves the tasks of allocation of control facilities for spacecraft (a subset of satellite range scheduling problem,

Institutional plan FY 1998--FY 2003

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-10-01

The Institutional Plan has been rearranged this year as a reflection of new Department of Energy (DOE) guidelines and to better illustrate the Laboratory`s mission-oriented focus. In Section 1 of this plan, the authors set forth their vision, mission, core competencies, strategic view, and related material. This section illustrates integration with the vision, mission, priorities, and core businesses of DOE. They define strategies, tactics, and guidelines and describe how they measure progress. In Section 2, they have elaborated on how they plan to address the Laboratory`s mission, describing programs and activities in the context of their role in this mission. Section 3 contains information on their approach to managing their business and operations. First they address the most critical issue safety. In this section, they confirm that Los Alamos is addressing the DOE critical success factors and describe the initiatives and plans that make their mission successful and leads them toward their vision. Section 4 contains details of their resources. 44 figs., 56 tabs.

COOLING WATER ISSUES AND OPPORTUNITIES AT U.S. NUCLEAR POWER PLANTS

International Nuclear Information System (INIS)

Vine, Gary

2010-01-01

This report has been prepared for the Department of Energy, Office of Nuclear Energy (DOE-NE), for the purpose of providing a status report on the challenges and opportunities facing the U.S. commercial nuclear energy industry in the area of plant cooling water supply. The report was prompted in part by recent Second Circuit and Supreme Court decisions regarding cooling water system designs at existing thermo-electric power generating facilities in the U.S. (primarily fossil and nuclear plants). At issue in the courts have been Environmental Protection Agency regulations that define what constitutes 'Best Technology Available' for intake structures that withdraw cooling water that is used to transfer and reject heat from the plant's steam turbine via cooling water systems, while minimizing environmental impacts on aquatic life in nearby water bodies used to supply that cooling water. The report was also prompted by a growing recognition that cooling water availability and societal use conflicts are emerging as strategic energy and environmental issues, and that research and development (R and D) solutions to emerging water shortage issues are needed. In particular, cooling water availability is an important consideration in siting decisions for new nuclear power plants, and is an under-acknowledged issue in evaluating the pros and cons of retrofitting cooling towers at existing nuclear plants. Because of the significant ongoing research on water issues already being performed by industry, the national laboratories and other entities, this report relies heavily on ongoing work. In particular, this report has relied on collaboration with the Electric Power Research Institute (EPRI), including its recent work in the area of EPA regulations governing intake structures in thermoelectric cooling water systems.

Sampling and Analysis Plan for the 233-S Plutonium Concentration Facility

International Nuclear Information System (INIS)

Mihalic, M.A.

1998-02-01

This Sampling and Analysis Plan (SAP) provides the information and instructions to be used for sampling and analysis activities in the 233-S Plutonium Concentration Facility. The information and instructions herein are separated into three parts and address the Data Quality Objective (DQO) Summary Report, Quality Assurance Project Plan (QAP), and SAP

Lac du Flambeau Band of Lake Superior Chippewa Indians Strategic Energy Plan

Energy Technology Data Exchange (ETDEWEB)

Bryan Hoover

2009-11-16

This plan discusses the current energy use on the Lac du Flambeau Reservation, the current status of the Tribe's energy program, as well as the issues and concerns with energy on the reservation. This plan also identifies and outlines energy opportunities, goals, and objectives for the Tribe to accomplish. The overall goal of this plan is to address the energy situation of the reservation in a holistic manner for the maximum benefit to the Tribe. This plan is an evolving document that will be re-evaluated as the Tribe's energy situation changes.

The big issue: environment and large dams

Energy Technology Data Exchange (ETDEWEB)

Rogers, Peter [Harvard Univ. (United States)

1999-09-01

Some of the environmental issues associated with large dams are discussed. Prior to commencement of construction of the Three Gorges dam in China in 1993, 50 years of planning and 20 years of environmental argument had taken place. The Chinese were conscious of the need to consider the environmental issues as a factor in attracting foreign investment for the world's biggest and most expensive dam. While the resettlement issues (1.2 M people were resettled) have dominated the current arguments, the other important issues are environment, economics and safety. Despite criticism from environmentalists, both at home and abroad, the Chinese went ahead with the project. With regard to resettlement, the Chinese appear to be much more considerate than some other countries in providing housing and agricultural land. Perhaps the main losses were suffered by cultural heritage sites and aquatic systems, rather than by the resettled population. (UK)

Planning for a Distributed Disruption: Innovative Practices for Incorporating Distributed Solar into Utility Planning

Energy Technology Data Exchange (ETDEWEB)

Mill, Andrew [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Barbose, Galen [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Seel, Joachim [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Dong, Changgui [National Renewable Energy Lab. (NREL), Golden, CO (United States); Mai, Trieu [National Renewable Energy Lab. (NREL), Golden, CO (United States); Sigrin, Ben [National Renewable Energy Lab. (NREL), Golden, CO (United States); Zuboy, Jarrett [Independent Consultant

2016-08-19

implemented to evaluate system needs, hosting capacities, and system investments needed to accommodate DPV deployment. 7) Estimating avoided losses associated with DPV: A time-differentiated marginal loss rate provides the most comprehensive estimate of avoided losses due to DPV, but no studies appear to use it. 8) Considering changes in DPV’s value with higher solar penetration: Innovative methods for addressing the value changes at high solar penetrations are lacking among the studies we evaluate. 9) Integrating DPV in planning across generation, transmission, and distribution: A few states and regions have started to develop more comprehensive processes that link planning forums, but there are still many issues to address.

Planning for a Distributed Disruption: Innovative Practices for Incorporating Distributed Solar into Utility Planning

Energy Technology Data Exchange (ETDEWEB)

Mills, Andrew D.; Barbose, Galen L.; Seel, Joachim; Dong, Changgui; Mai, Trieu; Sigrin, Ben; Zuboy, Jarett

2016-08-01

practices are being implemented to evaluate system needs, hosting capacities, and system investments needed to accommodate DPV deployment. (7) Estimating avoided losses associated with DPV: A time-differentiated marginal loss rate provides the most comprehensive estimate of avoided losses due to DPV, but no studies appear to use it. (8) Considering changes in DPV's value with higher solar penetration: Innovative methods for addressing the value changes at high solar penetrations are lacking among the studies we evaluate. (9) Integrating DPV in planning across generation, transmission, and distribution: A few states and regions have started to develop more comprehensive processes that link planning forums, but there are still many issues to address.

Equal employment opportunity plan development guidance

Energy Technology Data Exchange (ETDEWEB)

None

1978-09-01

The purpose of this publication is to provide instructions for the development of EEO Plans for Fiscal Year 1979. It supplements the National EEO Plan for the Department of Energy issued in August 1978 (DOE/S-0002). The material included should be used immediately as guidance to develop, document, and implement subordinate echelon commitments to EEO. A schedule for the development and submission of EEO Plans is included. Most of the continuing requirements will be published at a later date as part of the directives system. Any comments or helpful suggestions concerned with the program outlined would be appreciated by the Office of Equal Opportunity.

Environmental, planning, and communication strategies and experience for windfarm developments in Yorkshire

International Nuclear Information System (INIS)

Pitcher, K.; Wade-Smith, R.; Fawcett, F.

1991-01-01

Two windfarms are planned for development in Yorkshire: at Chelker, comprising 4 WEG MS3 wind turbines of total capacity 1.3MW, by Yorkshire Water; and Ovenden Moor, comprising 23 Vestas WD34 wind turbines of total capacity 9MW, by Yorkshire Windpower, a joint venture between Yorkshire Water and Yorkshire Electricity. In order for these windfarms to be successfully realised, it was necessary to develop strategies to manage the planning applications, produce the Environmental Statements and communicate to local, regional and national organisations, groups and individuals what these windfarms will really achieve. The paper will describe how these strategies were developed and will show how the communication framework was established with all of the consultees. The paper will illustrate examples of how this essential dialogue assisted in the formation of important areas of the Environmental Statements and how the windfarms will be positively viewed and received by the communities. Details of the established planning procedures and those still requiring development and implementation will be discussed in the paper. The progress, timescales and current position of the Chelker and Ovenden Moor windfarms will be summarised. (author)

MUSICAL LANGUAGE AND LEARNER`S PLANNING: WHEN THE TONES DON´T COINCIDE

Directory of Open Access Journals (Sweden)

Maria da Conceição Costa

2016-07-01

Full Text Available It´s about the music and its utilization in the initial years in the place it occupies deployment in class. By means of classroom observations with teachers of 2nd and 3th grade classes from a state public school in Pau dos Ferros city, RN and its respective plans, notes that in the lesson plans, the occupied place by music is focused on acquisition of contents approached in the subject taught on initial years. Both the lesson plans and the teaching practice have gaps in the clearly defined objectives, on coherence between what is placed in the plan into its items and the didactic transposition. Such finding contributes to an emptying of a work with the musical art while individual and collective professional that enable creative learner´s conduct relegating the educational role at school.

Unresolved safety issues summary. Volume 3, Number 3. Aqua book

International Nuclear Information System (INIS)

1981-01-01

The 'Unresolved Safety Issues' summary is designed to provide the management of the Nuclear Regulatory Commission with a quarterly overview of the progress and plans for completion of generic tasks addressing Unresolved Safety Issues reported to Congress pursuant to section 210 of The Energy Reorganization Act of 1974 as amended. This summary utilizes data collected from the Office of Nuclear Reactor Regulation, Office of Nuclear Regulatory Research, and the National Laboratories and is prepared by the office of Management and Program Analysis. The definition of what constitutes completion of an unresolved safety issue (USI) has recently been expanded to include the implementation of the technical resolution. This is in acknowledgement of the fact that real safety benefits occur only after the implementation has taken place. The schedules in this book include a milestone at the end of each action plan which represents the initiation of the implementation process both with respect to incorporation of the technical resolution in the NRC official guidance or requirements and also the application of changes to individual operating plants. The schedule for implementation will not normally be included in the task action plan(s) for the resolution of a USI since the nature and extent of the activities necessary to accomplish the implementation cannot normally be reasonably determined prior to the determination of a technical resolution. The progress and status for implementation of unresolved safety issues for which a technical resolution has been completed are reported specifically in a separate table provided in this summary

The Cossacks of the South of Russia in R.A. Fadeev’s geopolitical plans

Directory of Open Access Journals (Sweden)

Kuznetsov Oleg Viktorovich

2013-11-01

Full Text Available The political project of a conservative writer of political essays of the second half of the XIX c. R.A. Fadeev (1824–1883, in which a key part is assigned to the attraction of the Cossacks of Southern Russia to solving the pressing foreign policy issues, is analyzed. A conclusion that the Cossacks could be used as a militant vanguard, i.e. military force (infantry, cavalry, reconnaissance and an effective tool of the colonization of the suburbs of the Russian Empire – is drawn. The conditions under which R.A. Fadeev could implement his plans are revealed. The key condition is the preservation of the identity of the Cossacks as a class and as a sub-ethnos. The historical assessment of the R.A. Fadeev’s plans is given. According to the plans R.A. Fadeev, revived after the reforms of its military power, Russia should not only play a key role in international relations, but also strive for a first impact and then rule on its neighboring Asian and European territories. And in the perspective he saw the new world order, in which there would be two dominating superpowers, Russia and the United States. The Cossacks were assigned an important role in the implementation of these plans by the publicist.This geopolitical project, no matter how attractive it was not for the Russians at first glance, was a utopia. The publicist obviously overestimated the military and economic capabilities of contemporary Imperial Russia, the ability of the autocracy to the socio-economic and political renewal of the country corresponding to the demands of the times. Consequently, the Cossacks were not destined to play the role which was assigned to them by R.A. Fadeev. Althoughhe anticipated accurately the individual elements of the future world order established for several decades in the XX century.

Socioeconomic issues for the Bear River Watershed Conservation Land Area Protection Plan

Science.gov (United States)

Thomas, Catherine Cullinane; Huber, Christopher; Gascoigne, William; Koontz, Lynne

2012-01-01

The Bear River Watershed Conservation Area is located in the Bear River Watershed, a vast basin covering fourteen counties across three states. Located in Wyoming, Utah, and Idaho, the watershed spans roughly 7,500 squares miles: 1,500 squares miles in Wyoming; 2,700 squares miles in Idaho; and 3,300 squares miles in Utah (Utah Division of Water Resources, 2004). Three National Wildlife Refuges are currently contained within the boundary of the BRWCA: the Bear River Migratory Bird Refuge in Utah, the Bear Lake National Wildlife Refuge in Idaho, and the Cokeville Meadows National Wildlife Refuge in Wyoming. In 2010, the U.S. Fish and Wildlife Service conducted a Preliminary Project Proposal and identified the Bear River Watershed Conservation Area as having high-value wildlife habitat. This finding initiated the Land Protection Planning process, which is used by the U.S. Fish and Wildlife Service to study land conservation opportunities including adding lands to the National Wildlife Refuge System. The U.S. Fish and Wildlife Service proposes to include part of the Bear River Watershed Conservation Area in the Refuge System by acquiring up to 920,000 acres of conservation easements from willing landowners to maintain landscape integrity and habitat connectivity in the region. The analysis described in this report provides a profile of the social and economic conditions in the Bear River Watershed Conservation Area and addresses social and economic questions and concerns raised during public involvement in the Land Protection Planning process.

The Issues of Human Rights in the India-U.S. Relations

Directory of Open Access Journals (Sweden)

Zakharov Aleksey I.

2016-10-01

Full Text Available The article presents a brief overview of India-U.S. relations during the period of Narendra Modi’s government and Barack Obama’s administration. The author analyzes the dynamics of cooperation development after the victory of Bharatiya Janata Party in the 2014 Parliamentary elections in India and studies the key directions of bilateral agenda. The current condition of India-U.S. strategic dialogue and the influence of human rights issues on the countries’ cooperation are characterized. Since 2014 the states’ cooperation has been growing rapidly. The bilateral investment, trade and economic interdependence have significantly increased. Some experts and mass media note that Barack Obama and Narendra Modi are having friendly relations. From a different angle, a number of agreements between countries still remain unaccomplished. For instance, the U.S. support for India’s permanent seat in the United Nations Security Council, its accession to APEC and the implementation of nuclear deal have yet to be turned into achievement. Together with strengthening the bilateral strategic dialogue, the U.S. has intensified the criticism of India’s human rights record. The main part of it includes the cases of religious intolerance, which are observed in the United States Commission on International Religious Freedom reports and the remarks given by U.S. lawmakers and official representatives, including the Ambassador to India. Washington’s careful attention to the human rights issues and religious violence in particular is one of the major irritants in the U.S.-India relations. The engagement of Indian Americans in the local U.S. politics and their lobbying efforts in the context of U.S.-India relations are revealed. The author outlines the near-terms perspectives of bilateral cooperation.

Maintenance Implementation Plan for the 222-S Laboratory

International Nuclear Information System (INIS)

Stark, T.E.

1992-10-01

This Maintenance Implementation Plan (MIP) has been developed for the 222-S Laboratory at Hanford. It is based on assessments of the existing maintenance program to the requirements specified by US Department of Energy (DOE) Order 4330.4A, Maintenance Management Program (DOE 1990), Chapter II, Change 3. The results of these assessments were evaluated to determine corrective actions required. The 222-S Laboratory is currently supporting the waste management, chemical processing, and environmental monitoring programs presently under Westinghouse Hanford Company (Westinghouse Hanford) responsibility. This is done through quality analytical and process chemistry services

METHODOLOGICAL ISSUES OF CLINICAL TRIALS IN THE PEDIATRIC POPULATION

Directory of Open Access Journals (Sweden)

S.V. Topolyanskaya

2010-01-01

Full Text Available Conducting clinical trials on children population is a challenge both for organizers and pediatricians involved in trials. Difficulties in recruiting patients, a significant heterogenecity of the population, specific side reactions, difficulties in identifying the objective final points warrant the specific nature of designing clinical trials in pediatrics. The article illustrates key issues and methodology aspects: planning, design, control groups, patient recruitment. It stresses the need to carefully consider specific characteristics of a child’s system and multi-disciplinary approach involving a pediatrician at the early stages of planning, preliminary consultations with parent organizations, children and regulators.Key words: clinical trials, methodology, planning, design, patient recruitment, children. (Pediatric Pharmacology. – 2010; 7(5:6-10

U.S. nuclear fuel cycle regulatory issues on exclusion, exemption, and clearance

International Nuclear Information System (INIS)

Meck, R.A.

1997-01-01

The U.S. Nuclear Regulatory Commission is considering the use of exclusion and clearance in connection with the nuclear fuel cycle regulations. Clearance of licensed lands, buildings, structures, materials, and equipment could expose members of the public to radiation in addition to background. Establishing and implementing dose criteria for allowed concentrations of radioactivity in the various media raise challenging issues for the regulator. Clearance also raises significant regulatory issues, and these issues reflect trade-offs between concerns for protecting public health and safety, as well as other socioeconomic values and concerns. At the heart of the issues are the adequacy of risk analyses, acceptability of risks, underlying rationales, feasibility and cost of implementation, and exposures of the public to man-made radiation in relation to natural sources of radiation. (author)

State regulatory issues in acid rain compliance

International Nuclear Information System (INIS)

Solomon, B.D.; Brick, S.

1992-01-01

This article discusses the results of a US EPA workshop for state regulators and commission staff on acid rain compliance concerns. The topics of the article include the results of market-based emissions control, how emissions trading is expected to reduce emissions, public utility commissions approval of compliance plans, the purposes of the workshop, market information, accounting issues, regulatory process and utility planning, multi-state compliance planning, and relationship to other compliance issues

Issues in focus.

Science.gov (United States)

1994-08-01

The issues worldwide that deserve attention pertain to international migration, the education of women, family planning, missing female children, and prevention and control of AIDS cases. Migration outside country borders has been increasing due to economic and social disparities, and uncounted and unrecognized refugees are fleeing environmental disasters. The educational status of women has increased over the past 30 years. For example, female illiteracy has declined among women aged 20-24 years from 19% to 8% in Latin America, from 38% to 12% in eastern and western Asia, and from 80% to 49% in Africa. These improvements are significant, but the problem remains, where, for instance in Africa, there is still extensive illiteracy (75% of females aged under 25 years). A 1993 Population Action International Report states that low female educational levels and weak family planning and health programs are related to large family size and high child death rates. During the 1980s family planning was linked with ecological concerns. Progress has been made in the increase in contraceptive users in developing countries from 14% to 53% during 1965-70. Fertility has declined from 6.1 children per woman in the 1950s to 3.7. Kenya is a good example of a country with high fertility that reduced fertility through its emphasis on family planning. Obstacles to increased prevalence of contraception still remain. In Mexico more than 50% of public birth control services are provided to women in secret due to fear of their husband's abuse. Population pressure can result in the loss of girl children through higher mortality, better nutrition, neglect, or gender preference in the early fetal stages. The challenge of AIDS will be in caring for the sick and adjusting to social changes due to the expected increases in orphaned children.

Retirement planning: conceptualisation, challenges and policy options

OpenAIRE

Adenutsi, Deodat E.

2009-01-01

The central objective of this paper is to explain the concept and relevance of retirement planning within a vibrant Christian organisation such as the Assemblies of God’s Church. In particular, an attempt is made to expose participants to the theoretical relevance and application of the benefits of retirement planning to the church as an employer, and the pastors as employees of the church. Accordingly, issues related to the role of the church and beneficiary pastors and other full-time worke...

Planning in the human ecotone: Managing wild places on the Togiak National Wildlife Refuge

Science.gov (United States)

Stewart Allen

2002-01-01

The U.S. Fish and Wildlife Service is revising the long-range plan for Alaska’s Togiak National Wildlife Refuge, over half of which is designated as the Togiak Wilderness Area. Many of the planning issues are social rather than biological, involving public use and its effects on Refuge resources and opportunities. Planners, managers, and stakeholders are finding...

Critical human-factors issues in nuclear-power regulation and a recommended comprehensive human-factors long-range plan. Executive summary

International Nuclear Information System (INIS)

Hopkins, C.O.; Snyder, H.L.; Price, H.E.; Hornick, R.J.; Mackie, R.R.; Smillie, R.J.; Sugarman, R.C.

1982-08-01

This comprehensive long-range human factors plan for nuclear reactor regulation was developed by a Study Group of the Human Factors Society, Inc. This Study Group was selected by the Executive Council of the Society to provide a balanced, experienced human factors perspective to the applications of human factors scientific and engineering knowledge to nuclear power generation. The report is presented in three volumes. Volume 1 contains an Executive Summary of the 18-month effort and its conclusions. Volume 2 summarizes all known nuclear-related human factors activities, evaluates these activities wherever adequate information is available, and describes the recommended long-range (10-year) plan for human factors in regulation. Volume 3 elaborates upon each of the human factors issues and areas of recommended human factors involvement contained in the plan, and discusses the logic that led to the recommendations

Exploring women’s perceptions regarding successful investment planning practices

Directory of Open Access Journals (Sweden)

Elmarie Venter

2017-08-01

Aim: Therefore, the primary objective of this research was to investigate the factors that influence women’s perceived successful investment planning in the Nelson Mandela Bay area. After conducting a comprehensive literature study, six factors (independent variables, namely, values, attitudes, time horizon, personal life cycle, risks and returns, and investment knowledge, were identified as influencing the perceived successful investment planning (dependent variable of women. Setting: As this study focussed on the perceptions of women concerning the factors that influence successful investment planning, the target population was all women in the Nelson Mandela Bay area older than 20 years with some investment experience. Methods: A quantitative research methodology was followed, and data were collected from 207 women using a structured self-administered questionnaire. Results: The results of the multiple regression analysis revealed that only one independent variable emerged as having a significant influence on perceived successful investment planning of women, namely, investment knowledge. Conclusion: Based on the empirical results of this study, several recommendations have been made in an attempt to assist women to make more informed investment decisions and manage their investment planning more effectively as they progress through life.

5 CFR 2640.302 - Waivers issued pursuant to 18 U.S.C. 208(b)(3).

Science.gov (United States)

2010-01-01

... actual or potential profit or loss or cost of the matter to the company issuing the stock, the change in...) Requirements for issuing an individual waiver under 18 U.S.C. 208(b)(3). Pursuant to 18 U.S.C. 208(b)(3), an...) The type of interest that is creating the disqualification (e.g. stock, bonds, real estate, other...

Financial Planning and Financial Instruments: 2013 in Review, 2014 in Prospect

Directory of Open Access Journals (Sweden)

Mark Brimble

2013-09-01

Full Text Available The Global Financial Crisis (GFC; changes in regulation; issues in public perception and trust have contributed to a troubled 2013 for financial planners. As financial planning and wealth management providers seek to bolster their professional status, the Financial Planning Education Council’s National Curriculum and Accreditation Framework and ASIC’s minimum training requirements are also a space to watch. In prospect, 2014 will offer opportunities and challenges in the form of a changed government; regulatory changes; accreditation challenges and the hope of the recruitment of strong financial planning and wealth management professionals for the future.

Wilson's disease: {sup 31}P and {sup 1}H MR spectroscopy and clinical correlation

Energy Technology Data Exchange (ETDEWEB)

Sinha, Sanjib; Taly, A.B.; Prashanth, L.K. [National Institute of Mental Health and Neurosciences (NIMHANS), Department of Neurology, Bangalore (India); Ravishankar, S.; Vasudev, M.K. [National Institute of Mental Health and Neurosciences (NIMHANS), Department of Neuroimaging and Interventional Radiology, Bangalore (India)

2010-11-15

Proton ({sup 1}H) magnetic resonance spectroscopy (MRS) changes are noted in Wilson's disease (WD). However, there are no studies regarding membrane phospholipid abnormality using {sup 31}P MRS in these patients. We aimed to analyze the striatal spectroscopic abnormalities using {sup 31}P and {sup 1}H MRS in WD. Forty patients of WD (treated, 29; untreated,11) and 30 controls underwent routine MR image sequences and in vivo 2-D {sup 31}P and {sup 1}H MRS of basal ganglia using an image-selected technique on a 1.5-T MRI scanner. Statistical analysis was done using Student's t test. The mean durations of illness and treatment were 6.2 {+-} 7.4 and 4.8 {+-} 5.9 years, respectively. MRI images were abnormal in all the patients. {sup 1}H MRS revealed statistically significant reduction of N-acetyl aspartate (NAA)/choline (Cho) and NAA/creatine ratios in striatum ({sup 1}H MRS) of treated patients compared to controls. The mean values of phosphomonoesters (PME) (p < 0.0001), phosphodiesters (PDE) (p < 0.0001), and total phosphorus (TPh) (p < 0.0001) were elevated in patients compared to controls. Statistically significant elevated levels of ratio of PME/PDE (p = 0.05) observed in the striatum were noted in treated patients as compared to controls in the {sup 31}P MRS study. The duration of illness correlated well with increased PME/PDE [p < 0.001], PME/TPh [p < 0.05], and PDE/TPh [p < 0.05] and decreased NAA/Cho [p < 0.05] ratios. There was correlation of MRI score and reduced NAA/Cho ratio with disease severity. The PME/PDE ratio (right) was elevated in the treated group [p < 0.001] compared to untreated group. There is reduced breakdown and/or increased synthesis of membrane phospholipids and increased neuronal damage in basal ganglia in patients with WD. (orig.)

China’s Foreign Policy Toward North Korea: The Nuclear Issue

Science.gov (United States)

2012-12-01

black or white, what matters is it catches mice ,” represented China’s strategy. Among Western countries, China understood that rapprochement with...nonproliferation issue. Until 1970, China considered that superpowers used nuclear nonproliferation as a way to monopolize nuclear weapons. Thus, in

SKI's and SSI's comments on SKB's RandD/RDandD Programme 1986-2007; SKI:s och SSI:s synpunkter paa SKB:s FoU/Fud-program 1986-2007

Energy Technology Data Exchange (ETDEWEB)

Toverud, Oeivind (Bromma Geokonsult (Sweden))

2010-10-15

SKB has since 1986 submitted RDandD program every three years to former Nuclear Power Inspectorate (SKI) for review and evaluation. SKI and former Radiation Protection Inst. (SSI) have commented on a large number of issues in connection with the audits. The authorities' goal has been to influence the SKB's design of the RDandD programs, inter alia with a view to future repository applications to fulfill the requirements they are tested against. SKB plans to submit applications for the final repository for spent Fuel first quarter of 2011 and it is therefore important for Radiation Safety Authority (SSM) to follow up on SKB's handling of critical comments on RDandD programs. A starting point for this monitoring is to establish how SKB has dealt with major issues raised by authorities in the audits of the RDandD programs and in consultation process which has been linked to the programs. The follow-up is expected to be an important contribution to the planning and implementation of the examination of applications for nuclear fuel repository

U.S. Military Operations in Iraq: Planning, Combat, and Occupation

National Research Council Canada - National Science Library

Phillips, Kate; Lauth, Shane; Schenck, Erin

2006-01-01

On November 2, 2005, a colloquium entitled "U.S. Military Operations in Iraq: Planning, Combat and Occupation" was held in Washington, DC, at the Johns Hopkins School of Advanced International Studies (SAIS...

WD-repeat instability and diversification of the Podospora anserina hnwd non-self recognition gene family.

Science.gov (United States)

Chevanne, Damien; Saupe, Sven J; Clavé, Corinne; Paoletti, Mathieu

2010-05-06

Genes involved in non-self recognition and host defence are typically capable of rapid diversification and exploit specialized genetic mechanism to that end. Fungi display a non-self recognition phenomenon termed heterokaryon incompatibility that operates when cells of unlike genotype fuse and leads to the cell death of the fusion cell. In the fungus Podospora anserina, three genes controlling this allorecognition process het-d, het-e and het-r are paralogs belonging to the same hnwd gene family. HNWD proteins are STAND proteins (signal transduction NTPase with multiple domains) that display a WD-repeat domain controlling recognition specificity. Based on genomic sequence analysis of different P. anserina isolates, it was established that repeat regions of all members of the gene family are extremely polymorphic and undergoing concerted evolution arguing for frequent recombination within and between family members. Herein, we directly analyzed the genetic instability and diversification of this allorecognition gene family. We have constituted a collection of 143 spontaneous mutants of the het-R (HNWD2) and het-E (hnwd5) genes with altered recognition specificities. The vast majority of the mutants present rearrangements in the repeat arrays with deletions, duplications and other modifications as well as creation of novel repeat unit variants. We investigate the extreme genetic instability of these genes and provide a direct illustration of the diversification strategy of this eukaryotic allorecognition gene family.

Landslides along Highways: GIS-based Inventory and Planning Issues

Science.gov (United States)

Jaeger, Ann-Kathrin; Klose, Martin; Damm, Bodo

2015-04-01

assess landslide impacts and the effectiveness of measures for their mitigation. The landslide inventory is part of an ongoing study concerned with the problems of damage financing at low-volume roads in mountain areas with shrinking populations and fiscal deficits. Using the example of the Harz Mountains, a key research question refers to a comparison of the costs necessary to spend for safe road operations with the benefits from providing traffic connections to landslide-prone rural communities. This study combines the damage and loss data stored in the inventory with different data sets on traffic density, local population, and road financing. The research results contribute to the development of planning strategies for cost-efficient maintenance of highway infrastructures exposed to landslide hazards. References Bhandary, N.P., Yatabe, R., Dahal, R.K., Hasegawa, S., Inagaki, H., 2013. Areal distribution of large-scale landslides along highway corridors in central Nepal. Georisk 7, 1-20. Hungr, O., Evans, S.G., Hazzard, J., 1999. Magnitude and frequency of rock falls and rockslides along the main transportation corridors of southwestern British Columbia. Canadian Geotechnical Journal 36, 224-238 Klose, M., Damm, B., Terhorst, B., 2014b. Landslide cost modeling for transportation infrastructures: a methodological approach. Landslides, DOI 10.1007/s10346-014-0481-1. Saha, A.K., Arora, M.K., Gupta, R.P., Virdi, M.L., Csaplovics, E., 2005. GIS-based route planning in landslide-prone areas. International Journal of Geographical Information Science 19, 1149-1175.

N Area Final Project Program Plan

International Nuclear Information System (INIS)

Day, R.S.; Duncan, G.M; Trent, S.J.

1998-07-01

The N Area Final Project Program Plan is issued for information and use by the U.S. Department of Energy (DOE), the Environmental Restoration Contractor (ERC) for the Hanford Site, and other parties that require workscope knowledge for the deactivation of N Reactor facilities and remediation of the 100-N Area. This revision to the program plan contains the updated critical path schedule to deactivate N Reactor and its supporting facilities, cleanout of the N Reactor Fuel Storage Basin (105-N Basin), and remediate the 100-N Area. This document reflects notable changes in the deactivation plan for N Reactor, including changes in deactivation status, the N Basin cleanout task, and 100-N Area remediation

The U.S. Department of Energy Environmental Restoration and Waste Management Five-Year Plan

International Nuclear Information System (INIS)

Grimm, P.

1990-01-01

Within the first month after being confirmed as this country's sixth secretary of energy, Admiral James D. Watkins (US Navy, Retired) promised Congress that he would deliver a comprehensive plan that outlines specific actions to undertake over the next 5 yr to achieve compliance with US environmental laws and to begin to clean up and restore those sites that we have contaminated over the past 40 yr. The Environmental Restoration and Waste Management Five-Year Plan was published in August 1989. As the admiral committed, the plan established and documented an agenda for compliance and cleanup against which progress in the area of environmental restoration and waste management would be measured and specifically identified actions and commitments to achieve this progress. In November 1989, an additional chapter identifying the applied research, development, demonstration, testing, and evaluation (RDDT and E) activities that would support the implementation of the plan was published. Last June, the US Department of Energy (DOE) issued the first annual update of the 5-yr plan. This update covers the years 1992-1996, notes the progress achieved during the past year, and incorporates the scope of both the original plan and the RDDT and E plan. The plan is divided into five sections: corrective activities, environmental restoration, waste operations, technology development, and transportation. Each section explains DOE's overall policies and plans for achieving compliance and cleanup at DOE's nuclear-related facilities

Development plan of Pu NDA system using ZnS ceramic scintillator

International Nuclear Information System (INIS)

Kureta, Masatoshi; Soyama, Kazuhiko; Seya, Michio; Ohzu, Akira; Haruyama, Mitsuo; Takase, Misao; Sakasai, Kaoru; Nakamura, Tatsuya; Toh, Kentaro

2012-01-01

Alternative techniques to neutron detection by He-3 for nuclear security and safeguards systems are necessary to be developed since He-3 shortage is serious. With support of Japanese government (the Ministry of Education, Culture, Sports, and Technology), we have started an R and D project of Pu NDA system using ZnS ceramic scintillator. Here we present development plan, production of a new type of ZnS ceramic scintillator experimentally and basic design of a PCAS alternative Pu NDA system. We are planning the demonstration tests using the alternative NDA system comparing with the current PCAS in which the He-3 counters are installed. (author)

ANL site response for the DOE FY1994 information resources management long-range plan

Energy Technology Data Exchange (ETDEWEB)

Boxberger, L.M.

1992-03-01

Argonne National Laboratory's ANL Site Response for the DOE FY1994 Information Resources Management (IRM) Long-Range Plan (ANL/TM 500) is one of many contributions to the DOE information resources management long-range planning process and, as such, is an integral part of the DOE policy and program planning system. The Laboratory has constructed this response according to instructions in a Call issued in September 1991 by the DOE Office of IRM Policy, Plans and Oversight. As one of a continuing series, this Site Response is an update and extension of the Laboratory's previous submissions. The response contains both narrative and tabular material. It covers an eight-year period consisting of the base year (FY1991), the current year (FY1992), the budget year (FY1993), the plan year (FY1994), and the out years (FY1995-FY1998). This Site Response was compiled by Argonne National Laboratory's Computing and Telecommunications Division (CTD), which has the responsibility to provide leadership in optimizing computing and information services and disseminating computer-related technologies throughout the Laboratory. The Site Response consists of 5 parts: (1) a site overview, describes the ANL mission, overall organization structure, the strategic approach to meet information resource needs, the planning process, major issues and points of contact. (2) a software plan for DOE contractors, Part 2B, Software Plan FMS plan for DOE organizations, (3) computing resources telecommunications, (4) telecommunications, (5) printing and publishing.

ANL site response for the DOE FY1994 information resources management long-range plan

Energy Technology Data Exchange (ETDEWEB)

Boxberger, L.M.

1992-03-01

Argonne National Laboratory`s ANL Site Response for the DOE FY1994 Information Resources Management (IRM) Long-Range Plan (ANL/TM 500) is one of many contributions to the DOE information resources management long-range planning process and, as such, is an integral part of the DOE policy and program planning system. The Laboratory has constructed this response according to instructions in a Call issued in September 1991 by the DOE Office of IRM Policy, Plans and Oversight. As one of a continuing series, this Site Response is an update and extension of the Laboratory`s previous submissions. The response contains both narrative and tabular material. It covers an eight-year period consisting of the base year (FY1991), the current year (FY1992), the budget year (FY1993), the plan year (FY1994), and the out years (FY1995-FY1998). This Site Response was compiled by Argonne National Laboratory`s Computing and Telecommunications Division (CTD), which has the responsibility to provide leadership in optimizing computing and information services and disseminating computer-related technologies throughout the Laboratory. The Site Response consists of 5 parts: (1) a site overview, describes the ANL mission, overall organization structure, the strategic approach to meet information resource needs, the planning process, major issues and points of contact. (2) a software plan for DOE contractors, Part 2B, ``Software Plan FMS plan for DOE organizations, (3) computing resources telecommunications, (4) telecommunications, (5) printing and publishing.

A prioritization of generic safety issues

International Nuclear Information System (INIS)

Emrit, R.; Riggs, R.; Milstead, W.; Pittman, J.

1991-07-01

This report presents the priority rankings for generic safety issues and related to nuclear power plants. The purpose of these rankings is to assist in the timely and efficient allocation of NRC resources for the resolution of those safety issues that have a significant potential for reducing risk. The report focuses on the prioritization of generic safety issues. Issues primarily concerned with the licensing process or environmental protection and not directly related to safety have been excluded from prioritization. The prioritized issues include: TMI Action Plan items under development; previously proposed issues covered by Task Action Plans, except issues designated as Un-resolved Safety Issues (USIs) which had already been assigned high priority; and newly-proposed issues. Future supplements to this report will include the prioritization of additional issues. The safety priority rankings are High, Medium, Low, and Drop and have been assigned on the basis of risk significance estimates, the ratio of risk to costs and other impacts estimated to result if resolutions of the safety issues were implemented, and the consideration of uncertainties and other quantitative or qualitative factors. To the extent practical, estimates are quantitative. 1310 refs

A Study on Strategic Planning and Procurement of Medicals in Uganda’s Regional Referral Hospitals

Science.gov (United States)

2016-01-01

This study was an analysis of the effect of strategic planning on procurement of medicals in Uganda’s regional referral hospitals (RRH’s). Medicals were defined as essential medicines, medical devices and medical equipment. The Ministry of Health (MOH) has been carrying out strategic planning for the last 15 years via the Health Sector Strategic Plans. Their assumption was that strategic planning would translate to strategic procurement and consequently, availability of medicals in the RRH’s. However, despite the existence of these plans, there have been many complaints about expired drugs and shortages in RRH’s. For this purpose, a third variable was important because it served the role of mediation. A questionnaire was used to obtain information on perceptions of 206 respondents who were selected using simple random sampling. 8 key informant interviews were held, 2 in each RRH. 4 Focus Group Discussions were held, 1 for each RRH, and between 5 and 8 staff took part as discussants for approximately three hours. The findings suggested that strategic planning was affected by funding to approximately 34% while the relationship between funding and procurement was 35%. The direct relationship between strategic planning and procurement was 18%. However when the total causal effect was computed it turned out that strategic planning and the related variable of funding contributed 77% to procurement of medicals under the current hierarchical model where MOH is charged with development of strategic plans for the entire health sector. Since even with this contribution there were complaints, the study proposed a new model called CALF which according to a simulation, if adopted by MOH, strategic planning would contribute 87% to effectiveness in procurement of medicals. PMID:28299158

Is the IAEA's Safeguard Strategic Plan Sufficient?

International Nuclear Information System (INIS)

Sokolski, H.; Gilinsky, V.

2015-01-01

IAEA safeguards have much improved and the Safeguards Department is commendably planning to further its technical capabilities and to make full use of its authority. Will this be enough to keep countries from exploiting nuclear power programmes to develop nuclear weapons, or to be in a position to do so rapidly should they so decide? Depending on nuclear programmes developments worldwide, especially on expansions in enrichment and reprocessing, and on how international affairs unfold, the answer may well be no. The fundamental limitations on the Department's ability to prevent proliferation are not technical, but conceptual. The Department is clearly motivated to carry out its technical activities competently. Yet it takes a relatively passive view of its role in the worldwide development of nuclear power-whatever technology comes into use, and whoever deploys it, the Department promises to exert its best effort to safeguard. In our view the Department should be more open about what it can or cannot realistically safeguard, and therefore what technology is permissible for deployment in national programmes. The Department's Strategic Plan says at the outset that its verifications assist the Agency to fulfil its statutory objective to ''accelerate and enlarge the contribution of atomic energy. . . '' The Department should judge itself by how well it promotes international security, not by its contribution to expanding nuclear power use. The Department's Vision includes advancing toward a nuclear weapons free world. That vision should include keeping states from deploying technologies that put them within easy reach of nuclear weapons. Our paper will suggest how the Department might supplement its current plan to best accomplish this. (author)

Sandia National Laboratories Institutional Plan FY1994--1999

Energy Technology Data Exchange (ETDEWEB)

1993-10-01

This report presents a five year plan for the laboratory. This plan takes advantage of the technical strengths of the lab and its staff to address issues of concern to the nation on a scope much broader than Sandia`s original mission, while maintaining the general integrity of the laboratory. The plan proposes initiatives in a number of technologies which overlap the needs of its customers and the strengths of its staff. They include: advanced manufacturing technology; electronics; information and computational technology; transportation energy technology and infrastructure; environmental technology; energy research and technology development; biomedical systems engineering; and post-cold war defense imperatives.

Citizens and the planning of sustainability of mining

DEFF Research Database (Denmark)

Hoffmann, Birgitte

2014-01-01

will have a large impact on the citizen’s everyday life through the ongoing changes of settlement patterns and livelihoods. The key question of this paper is how the citizens may inform and influence the sustainability of planning and implementation of local raw material projects and urban planning. Further...... that the social, economic and environmental sustainability will depend on the degree to which the citizens are engaged in both local developments of specific mining projects, as well as in societal planning where multiple and complex issues are at stake such as urban settlement patterns, cultures, livelihood...

The 13 february action plan and the prospects for the North Korean nuclear issue

Energy Technology Data Exchange (ETDEWEB)

Narushige, Muchishita

2007-07-01

involved. In agreeing to the plan, all parties made minimum necessary concessions, and gained minimum satisfactory outcome. For example, North Korea succeeded in bringing the United States back on the engagement track, but it had to freeze the important part of its nuclear facilities and be satisfied with 50,000 tons of HFO, a tenth of the amount that North Korea received annually under the 1994 Agreed Framework. The United States had North Korea committed to the freeze of its nuclear facility again at the price far cheaper than in 1994, but had to soften its North Korea policy at the risk of appearing to give in to North Korea's brinkmanship diplomacy and reward its 'bad behavior', or nuclear test more specifically. China and South Korea successfully persuaded the United States to go back on the engagement track. But to compensate for the U.S. concession, China had to provide strong political leadership, and South Korea had to bear the financial cost involved in implementing the Action Plan. Japan got upset about the shift in the U.S. position since the policy change left Japan alone on the containment track. However, it was not such a bad deal for Japan to be able to have North Korea's nuclear facilities frozen without making substantial financial contributions as it did under the Agreed Framework. The U.S. policy toward North Korea seems to have been significantly affected by the developments in Iraq and Iran. The United States has decided to increase its commitment, particularly military commitment, to the situations in these countries, and the decision made it necessary for it to reduce its commitment to North Korea. Given the high priorities put on Iraq and Iran, North Korea policy was relatively expendable for the United States. This assessment might sound somewhat puzzling because the United States has become more engaged with North Korea diplomatically. However, it was the reduction in U.S. policy commitment to North Korea in the sense that the

Planning of renewables schemes: Deliberative and fair decision-making on landscape issues instead of reproachful accusations of non-cooperation

International Nuclear Information System (INIS)

Wolsink, Maarten

2007-01-01

The main issues related to successful implementation policies concern the socio-economic institutions that are conditional to planning in the energy policy domain, but also in the domain of spatial planning. Successful investments and the siting of renewable power plants eventually determine the success rate of national efforts in establishing renewable capacity. Central planning usually has several objectives and these often have a detrimental effect on the goal of renewable energy application. Current problems related to implementation decisions concerning wind power schemes are an example to those who will be faced by other renewable power plants, notably biomass. Regarding community acceptance of wind power schemes, the visual evaluation of the impact of wind power on the values of the landscape is by far the most dominant factor in explaining opposition or support. Type of landscape fully overshadows other attitudinal attributes, as well as other visual and scenic factors such as the design of wind turbines and wind farms, and the number and the size of turbines. Planning regimes and decision-making practices that really enhance the implementation processes of renewable energy require 'strong' ecological modernization. This means institutional changes that create involvement and trust of actors at the actual implementation level. Local opposition cannot be explained by the egotistical motives of local residents. When the inclination to behave according to (supposed) backyard motives is investigated, the scale to measure this phenomenon appears to indicate commitment to equity issues and fairness of decision-making. Hence, for wind power, local involvement to represent the local values of site-specific landscapes is crucial. For other renewables the source-specific features are different, but conflicts can be expected as well because the fairness of implementation decisions will be equally significant

New Tsunami Response, Mitigation, and Recovery Planning "Playbooks" for California (USA) Maritime Communities

Science.gov (United States)

Wilson, R. I.; Lynett, P. J.; Miller, K.; Eskijian, M.; Dengler, L. A.; Ayca, A.; Keen, A.; Admire, A. R.; Siegel, J.; Johnson, L. A.; Curtis, E.; Hornick, M.

2015-12-01

The 2010 Chile and 2011 Japan tsunamis both struck the California coast offering valuable experience and raised a number of significant issues for harbor masters, port captains, and other maritime entities. There was a general call for more planning products to help guide maritime communities in their tsunami response, mitigation, and recovery activities. The State of California is working with the U.S. Federal Emergency Management Agency (FEMA), the U.S. National Tsunami Hazard Mitigation Program (NTHMP), and other tsunami experts to provide communities with new tsunami planning tools to address these issues: Response Playbooks and plans have been developed for ports and harbors identifying potential tsunami current hazards and related damage for various size events. Maps have been generated showing minor, moderate, and severe damage levels that have been linked to current velocity thresholds of 3, 6, and 9 knots, respectively. Knowing this information allows harbor personnel to move ships or strengthen infrastructure prior to the arrival of distant source tsunamis. Damage probability tools and mitigation plans have been created to help reduce tsunami damage by evaluating the survivability of small and large vessels in harbors and ports. These results were compared to the actual damage assessments performed in California and Japan following the 2011 Japanese tsunami. Fragility curves were developed based on current velocity and direction to help harbor and port officials upgrade docks, piles, and related structures. Guidance documents are being generated to help in the development of both local and statewide recovery plans. Additional tools, like post-tsunami sediment and debris movement models, will allow harbors and ports to better understand if and where recovery issues are most likely to occur. Streamlining the regulatory and environmental review process is also a goal of the guidance. These maritime products and procedures are being integrated into guidance

Women’s Opinion about Women’s Rights regarding Family Planning in Hegarmanah Village, Jatinangor Subdistrict, West Java in 2013

Directory of Open Access Journals (Sweden)

Suzanne Saw

2015-09-01

Full Text Available Background: Universal Declaration of Human Rights stated that all mankind have equal right and dignity. Both woman and man have rights regarding family planning. It is often assumed that in developing country, women do not consider their rights in family planning decision making process. This study was carried out to determine the opinion of women regarding women’s rights in family planning. Methods: A descriptive study was carried out to 99 respondents during the period of August to October 2013, in Hegarmanah village, Jatinangor subdistrict. The inclusion criteria were women aged 15–49 years old, able to speak Bahasa Indonesia, and agreed to participate. Variables for this study were the opinions of the respondents regarding woman’s rights in family planning which were represented in 12 questions. Collected data were presented as percentages shown in tables. Results: Most of the respondents stated that they had the rights in family planning decision making, including choosing contraceptive methods, number of children, and spacing of each child. However, all of the respondents agreed that men should be involved in it. More than half of the respondents stated that they asked opinion from family member regarding family planning especially their mothers. Cultural norms did not influence the family planning decision making. However, religion influenced the family planning decision making. Conclusions: Majority of the women in Hegarmanah village have the role to make decision on family planning by considering the opinions of their spouses, other family members, friends and their religions.

Developing The Organized Village of Kasaan's Strategic Energy Plan

Energy Technology Data Exchange (ETDEWEB)

Hamar, Glenn P. [The Organized Village of Kasaan, Ketchikan, AK (United States)

2013-02-01

The overall goal of this project is to create a Tribal Energy Action Plan that will serve as the Tribe's blueprint for creating long term energy self sufficiency. The Plan will be developed with input from a committed group of key stakeholders and landowners in the area, will be based on sound data and research, and will address both supply side options of the development of sustainable energy sources, as well as demand-side options for reducing energy consumption. The resulting plan will include defined comprehensive energy strategies and built upon a baseline assessment of where the Tribe currently is in terms of alternative and renewable energy activities; a vision of where the Tribe wants to go; and an action plan of how the Tribe will reach its vision including the identification of viable energy options based on the long-term strategic plan of the Tribe.

40 CFR 300.220 - Related Title III issues.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 27 2010-07-01 2010-07-01 false Related Title III issues. 300.220 Section 300.220 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SUPERFUND, EMERGENCY... PLAN Planning and Preparedness § 300.220 Related Title III issues. Other related Title III requirements...

31 CFR 598.409 - Credit extended and cards issued by U.S. financial institutions.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Credit extended and cards issued by U... NARCOTICS KINGPIN SANCTIONS REGULATIONS Interpretations § 598.409 Credit extended and cards issued by U.S... existing credit agreements, including, but not limited to, charge cards, debit cards, or other credit...

Efficient energy utilization and environmental issues applied to power planning

International Nuclear Information System (INIS)

Campbell, Hector; Montero, Gisela; Perez, Carlos; Lambert, Alejandro

2011-01-01

This document shows the importance of policies for electric energy savings and efficient energy utilization in power planning. The contributions of economic, social, and environmental items were evaluated according to their financial effects in the delay of investments, reduction of production costs and decrement of environmental emissions. The case study is Baja California, Mexico; this system has a unique primary source: geothermal energy. Whether analyzing the planning as usual or planning from the supply side, the forecast for 2005-2025 indicates that 4500 MW additional installed capacity will be required (3-times current capacity), representing an investment that will emit 12.7 Mton per year of CO 2 to the atmosphere and will cost US$2.8 billion. Systemic planning that incorporates polices of energy savings and efficiency allows the reduction of investments and pollutant emissions. For example, a reduction of 20% in the growth trend of the electricity consumption in the industrial customers would save US$10.4 billion over the next 20 years, with a potential reduction of 1.6 Mton/year of CO 2 . The increase in geothermal power generation is also attractive, and it can be combined with the reduction of use and energy losses of utilities, which would save US$13.5 billion and prevent the discharge of 8.5 Mton/year of CO 2 . - Highlights: → We contrast power planning methods for supply electricity for economy development. → Importance of policies for electricity savings and efficient use in power planning. → Systemic planning facilitates decision-making process for electricity optimization. → Supply-side planning will cause climb in prices and loss of energy self-sufficiency. → Power planning should be immersed in an environment of appropriate energy policies.

Planning for the Transition to Long-Term Stewardship at Three U.S. Department of Energy-Chicago Operations Office Facilities

International Nuclear Information System (INIS)

Moos, L. P.; Ditmars, J. D.; Heston, S. L.; Granzen, G. A.; Holzemer, M. J.; Bennett, D. B.

2003-01-01

This paper describes a pilot study that resulted in the generation of draft planning documents for the upcoming transition from remediation construction to long-term stewardship at three national laboratories managed by the U.S. Department of Energy (DOE)-Chicago Operations Office (CH). The remediation construction work at these facilities is being completed under the DOE's Office of Environmental Management (EM) Program. Once the remediation is complete, the responsibility for long-term stewardship (LTS) of the closed waste sites is expected to be transferred to the DOE organization responsible for managing each of the three facilities (i.e., the site landlord). To prepare for this transfer, an extensive planning effort is required. This pilot study utilized the DOE guidance in effect at the time to (1) develop a series of documents identifying applicable requirements that the LTS Programs will need to satisfy, issues that need to be resolved before the transfer can proceed, and criteria to be used to determine when active remediation is complete and a given site is ready for transfer to the LTS Program; (2) examine alternate structures for possible LTS Programs; and (3) develop draft LTS Implementation Plans. This advanced planning effort yielded a number of observations and lessons learned that are applicable to any facility approaching the end of its remediation construction phase

Groundwater Protection Program Management Plan for the U.S. Department of Energy Y-12 National Security Complex, Oak Ridge, Tennessee

Energy Technology Data Exchange (ETDEWEB)

Elvado Environmental LLC; Environmental Compliance Department Environment, Safety, and Health Division Y-12 National Security Complex

2004-03-31

This document presents the Groundwater Protection Program (GWPP) management plan for the U.S. Department of Energy (DOE) Y-12 National Security Complex (hereafter referenced as Y-12). The Y-12 GWPP functions as the primary point-of-contact for groundwater-related issues at Y-12, provides stewardship of the extensive network of groundwater monitoring wells at Y-12, and serves as a resource for technical expertise, support, and historical data for groundwater-related activities at Y-12. These organizational functions each serve the primary programmatic purpose of the GWPP, which is to ensure that groundwater monitoring activities within areas under Y-12 administrative control provide representative data in compliance with the multiple purposes of applicable state and federal regulations, DOE orders, and the corporate policies of BWXT Y-12, L.L.C. (hereafter referenced as BWXT), the Y-12 management and operations (M&O) contractor for DOE. This GWPP management plan addresses the requirements of DOE Order 450.1 (BWXT Y12 S/RID) regarding the implementation of a site-wide approach for groundwater protection at each DOE facility. Additionally, this plan is a ''living'' document that is reviewed annually, revised and reissued every three years, and is formatted to provide for updating individual sections independent of the rest of the document. Section 2 includes a short description of the groundwater system at Y-12, the history of groundwater monitoring at Y-12 and the corresponding evolution of the GWPP, and an overview of ongoing Y-12 groundwater monitoring activities. Section 3 describes the key elements of the GWPP management strategy. Organizational roles and responsibilities of GWPP personnel are outlined in Section 4. Section 5 presents an overview of the GWPP project plans for applicable programmatic elements. Section 6 lists the reports, plans, and documents that are referenced for technical and administrative details.

Italy’s “Industry 4.0” Plan: A labour law analysis

Directory of Open Access Journals (Sweden)

Michele Tiraboschi

2016-12-01

Full Text Available New technologies and productive models lie at the heart of so-called Indus-try 4.0, a concept which has recently entered socio-economic and political discourse in a number of countries. Lately, Italy too has presented an action plan on Industry 4.0 and some operational measures on this issue have al-ready been envisaged in the Budget Law for 2017. Consequently, the aim of this paper is to look at Italy’s Industry 4.0 plan, focusing on consequences arising from labour law. The labour law perspective has been given scant consideration in the public debate, seeing that so far the latter has given pri-ority on technological aspects and on economic resources needed to imple-ment the plan. An approach of this kind enables us to appreciate the major changes that the Industry 4.0 paradigm will bring about in labour markets – either inside or outside companies – and in industrial relations. The idea of labour and that of doing business will also be questioned, leading to the conclusion that labour rules and active policies can also be factors enabling new productive processes. Examining the major challenges posed by Indus-try 4.0 to workers and employers (e.g. the crisis of subordination, the new roles of skills, the risk of technological unemployment, new decentralized and participatory forms of collective bargaining, this paper sets out to iden-tify actions and perspectives to manage current changes, focusing on work-ers rather than on those technologies that will be used to work in the years to come. In the authors’ opinion, this perspective might help raise awareness that labour law is not only tasked with providing protection and resources and with favouring production, but it has important functions in historical and political terms. Therefore, this branch of law is not doomed to be set aside following the demise of Fordism, but it will innovate over time to ena-ble and balance the new productive model underlying Industry 4.0., particu

Planning Cultures and Histories: Influences on the Evolution of Planning Systems and Spatial Development Patterns

NARCIS (Netherlands)

Stead, D.; de Vries, J.; Tasan-Kok, T.

2015-01-01

This special issue addresses the influences of planning cultures and histories on the evolution of planning systems and spatial development. As well as providing an international comparative perspective on these issues, the collection of articles also engages in a search for new conceptual

31 CFR 593.409 - Credit extended and cards issued by U.S. financial institutions.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Credit extended and cards issued by U... LIBERIAN REGIME OF CHARLES TAYLOR SANCTIONS REGULATIONS Interpretations § 593.409 Credit extended and cards..., including, but not limited to, charge cards, debit cards, or other credit facilities issued by a U.S...

31 CFR 587.408 - Credit extended and cards issued by U.S. financial institutions.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Credit extended and cards issued by U... Credit extended and cards issued by U.S. financial institutions. Section 587.201 on dealing in property... institutions from performing under any existing credit agreements, including, but not limited to, charge cards...

31 CFR 547.409 - Credit extended and cards issued by U.S. financial institutions.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Credit extended and cards issued by U... DEMOCRATIC REPUBLIC OF THE CONGO SANCTIONS REGULATIONS Interpretations § 547.409 Credit extended and cards..., including, but not limited to, charge cards, debit cards, or other credit facilities issued by a U.S...

SWiFT Software Quality Assurance Plan.

Energy Technology Data Exchange (ETDEWEB)

Berg, Jonathan Charles [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2016-01-01

This document describes the software development practice areas and processes which contribute to the ability of SWiFT software developers to provide quality software. These processes are designed to satisfy the requirements set forth by the Sandia Software Quality Assurance Program (SSQAP). APPROVALS SWiFT Software Quality Assurance Plan (SAND2016-0765) approved by: Department Manager SWiFT Site Lead Dave Minster (6121) Date Jonathan White (6121) Date SWiFT Controls Engineer Jonathan Berg (6121) Date CHANGE HISTORY Issue Date Originator(s) Description A 2016/01/27 Jon Berg (06121) Initial release of the SWiFT Software Quality Assurance Plan

The U.S. program for fusion nuclear technology development

International Nuclear Information System (INIS)

Clarke, J.F.; Haas, G.M.

1989-01-01

The Fusion Nuclear Technology (FNT) research and development program in the United States is shaped by a hierarchy of documents and by the environment for nuclear energy existing in the United States. The fission nuclear industry in the United States has suffered problems with public perception of safety, waste disposal issues, and economics as influenced by safety and environmental issues. For fusion to be a viable energy alternative, it must offer significant improvements in these areas. The hierarchy of documents defining objectives, plans, and strategy of the U.S. FNT program consists of the Magnetic Fusion Program Plan (MFPP) (February 1985), the Technical Planning Activity Final Report (January 1987), the Finesse Program Report (January 1987), and the Blanket Comparison and Selection Study Final Report (September 1984). In addition, two other documents are also significant in shaping FNT policy. These are the IEA report on Material for Fusion (December 1986) and the Summary of the Report of the Senior Committee on Environmental, Safety, and Economic Aspects of Magnetic Fusion Energy (September 1987). The U.S. Magnetic Fusion Program Plan defines four key technical issues (magnetic confinement systems, properties of burning plasmas, fusion nuclear technology, and fusion materials). (orig./KP)

WD40-repeat proteins in plant cell wall formation: current evidence and research prospects

Directory of Open Access Journals (Sweden)

Gea eGuerriero

2015-12-01

Full Text Available The metabolic complexity of living organisms relies on supramolecular protein structures which ensure vital processes, such as signal transduction, transcription, translation and cell wall synthesis. In eukaryotes WD40-repeat (WDR proteins often function as molecular hubs mediating supramolecular interactions. WDR proteins may display a variety of interacting partners and participate in the assembly of complexes involved in distinct cellular functions. In plants, the formation of lignocellulosic biomass involves extensive synthesis of cell wall polysaccharides, a process that requires the assembly of large transmembrane enzyme complexes, intensive vesicle trafficking, interactions with the cytoskeleton, and coordinated gene expression. Because of their function as supramolecular hubs, WDR proteins could participate in each or any of these steps, although to date only few WDR proteins have been linked to the cell wall by experimental evidence. Nevertheless, several potential cell wall-related WDR proteins were recently identified using in silico aproaches, such as analyses of co-expression, interactome and conserved gene neighbourhood. Notably, some WDR genes are frequently genomic neighbours of genes coding for GT2-family polysaccharide synthases in eukaryotes, and this WDR-GT2 collinear microsynteny is detected in diverse taxa. In angiosperms, two WDR genes are collinear to cellulose synthase genes, CESAs, whereas in ascomycetous fungi several WDR genes are adjacent to chitin synthase genes, chs. In this Perspective we summarize and discuss experimental and in silico studies on the possible involvement of WDR proteins in plant cell wall formation. The prospects of biotechnological engineering for enhanced biomass production are discussed.

Proceedings - Limits of Acceptable Change and related planning processes: Progress and future directions

Science.gov (United States)

Stephen F. McCool; David N. Cole

1997-01-01

Experience with Limits of Acceptable Change (LAC) and related planning processes has accumulated since the mid-1980's. These processes were developoed as a means of dealing with recreation carrying capacity issues in wilderness and National Parks. These processes clearly also have application outside of protected areas and to issues other than recreation...

7 CFR 1210.303 - Plan.

Science.gov (United States)

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false Plan. 1210.303 Section 1210.303 Agriculture... PLAN Watermelon Research and Promotion Plan Definitions § 1210.303 Plan. Plan means this watermelon research and promotion Plan issued by the Secretary pursuant to the Act. ...

40 CFR 52.970 - Identification of plan.

Science.gov (United States)

2010-07-01

... Revision of Bubble Permit. Issued 10/17/84, amended 07/20/89. Ref 52.999(c)(53) Vista Chemical Company... Submitted as part of the Baton Rouge, LA Post-1996 ROP Plan (e) EPA approved nonregulatory provisions and.../subject State approval/effective date EPA approval date Comments LA. R.S. of 1950. Title 40, Chapter 12...

Women’s experiences after Planned Parenthood’s exclusion from a family planning program in Texas☆

Science.gov (United States)

Woo, C. Junda; Alamgir, Hasanat; Potter, Joseph E.

2016-01-01

Objective We assessed the impact on depot medroxyprogesterone continuation when a large care provider was banned from a state-funded family planning program. Study Design We used three methods to assess the effect of the ban: (a) In a records review, we compared how many state program participants returned to two Planned Parenthood affiliates for a scheduled dose of depot medroxyprogesterone acetate (DMPA) immediately after the ban; (b) We conducted phone interviews with 224 former Planned Parenthood patients about DMPA use and access to contraception immediately after the ban; (c) We compared current contraceptive method of our interviewees to that of comparable DMPA users in the National Survey of Family Growth 2006–2010 (NSFG). Results (a) Fewer program clients returned for DMPA at a large urban Planned Parenthood, compared to a remotely located affiliate (14.4%, vs. 64.8%), reflecting different levels of access to alternative providers in the two cities. (b) Among program participants who went elsewhere for the injection, only 56.8% obtained it at no cost and on time. More than one in five women missed a dose because of barriers, most commonly due to difficulty finding a provider. (c) Compared to NSFG participants, our interviewees used less effective methods of contraception, even more than a year after the ban went into effect. Conclusions Injectable contraception use was disrupted during the rollout of the state-funded family planning program. Women living in a remote area of Texas encountered more barriers. Implications Requiring low-income family planning patients to switch healthcare providers has adverse consequences. PMID:26680757

Impact of occupational issues on DOE's environmental restoration program

International Nuclear Information System (INIS)

Siegel, M.R.; Lesperance, A.M.; Smith, D.

1992-01-01

The U.S. Department of Energy (DOE) is in the midst of a 30-yr, multi-billion-dollar environmental restoration program for most of the facilities included in its nuclear weapons complex. Long-term planning efforts are under way to identify strategies and approaches for carrying out this extraordinarily complicated task. The DOE has already entered into interagency agreements with the U.S. Environmental Protection Agency and states for many of its environmental restoration sites. These agreements set legally enforceable deadlines for cleanup activities at these sites. In addition, DOE has made other commitments to Congress and the public regarding its environmental restoration schedule. Thousands of workers will be directly involved in environmental restoration activities at DOE sites. Cleanup activity will be carried out in environments involving potential exposure to highly toxic chemical substances and radionuclides. It is inevitable that occupational safety and health (OSH) issues will become both critical and highly visible to DOE. The OSH issues associated with cleanup activities will likely attract the attention of workers, unions, the media, regulators, and the public. This paper reviews three case studies describing OSH activities in DOE's environmental restoration program. These case studies will help alert DOE officials to ways that various OSH issues should be considered when planning environmental restoration activities. This activity is being coordinated with other DOE work to identify occupational requirements that are applicable to DOE cleanup work

Calendar Year 1997 Annual Groundwater Monitoring Report For The Upper East Fork Poplar Creek Hydrogeologic Regime At The U.S. Department of Energy Y-12 Plant, Oak Ridge, Tennessee

Energy Technology Data Exchange (ETDEWEB)

Jones, S.B.

1998-02-01

This report contains the groundwater monitoring data obtained during calendar year (CY) 1997 in compliance with the Resource Conservation Wd Recovery Act (RCRA) post-closure permit (PCP) for the Upper East Fork Poplar Creek Hydrogeologic Regime (East Fork Regime) at the U.S. Department of Energy (DOE) Y-12 Plant in Oak Ridge, Tennessee. Issued by the Tennessee Department of Environment and Conservation (TDEC), the PCP defines the RCRA post-closure corrective action monitoring requirements for the portion of the groundwater contaminant plume that has migrated into the East Fork Regime ftom the S-3 Ponds, a closed RCW-regulated former surface impoundment located in Bear Creek Valley near the west end of the Y-12 Plant. In addition to the RCIL4 post-closure corrective action monitoring results, this report contains the groundwater and surface water monitoring data obtained during CY 1997 to fulfill requirements of DOE Order 5400.1.

Waste Isolation Pilot Plant disposal phase supplemental environmental impact statement. Implementation plan

Energy Technology Data Exchange (ETDEWEB)

NONE

1996-05-01

The Implementation Plan for the Waste Isolation Pilot Plant Disposal Phase Supplemental Environmental Impact Statement (SEIS-II) has two primary purposes: (1) To report on the results of the scoping process (2) To provide guidance for preparing SEIS-II SEIS-II will be the National Environmental Policy Act (NEPA) review for WIPP`s disposal phase. Chapter 1 of this plan provides background on WIPP and this NEPA review. Chapter 2 describes the purpose and need for action by the Department of Energy (hereafter DOE or the Department), as well as a description of the Proposed Action and alternatives being considered. Chapter 3 describes the work plan, including the schedule, responsibilities, and planned consultations with other agencies and organizations. Chapter 4 describes the scoping process, presents major issues identified during the scoping process, and briefly indicates how issues will be addressed in SEIS-II.

Piping research program plan

International Nuclear Information System (INIS)

1988-09-01

This document presents the piping research program plan for the Structural and Seismic Engineering Branch and the Materials Engineering Branch of the Division of Engineering, Office of Nuclear Regulatory Research. The plan describes the research to be performed in the areas of piping design criteria, environmentally assisted cracking, pipe fracture, and leak detection and leak rate estimation. The piping research program addresses the regulatory issues regarding piping design and piping integrity facing the NRC today and in the foreseeable future. The plan discusses the regulatory issues and needs for the research, the objectives, key aspects, and schedule for each research project, or group of projects focussing of a specific topic, and, finally, the integration of the research areas into the regulatory process is described. The plan presents a snap-shot of the piping research program as it exists today. However, the program plan will change as the regulatory issues and needs change. Consequently, this document will be revised on a bi-annual basis to reflect the changes in the piping research program. (author)

Aviation Safety Issues Database

Science.gov (United States)

Morello, Samuel A.; Ricks, Wendell R.

2009-01-01

The aviation safety issues database was instrumental in the refinement and substantiation of the National Aviation Safety Strategic Plan (NASSP). The issues database is a comprehensive set of issues from an extremely broad base of aviation functions, personnel, and vehicle categories, both nationally and internationally. Several aviation safety stakeholders such as the Commercial Aviation Safety Team (CAST) have already used the database. This broader interest was the genesis to making the database publically accessible and writing this report.

Facility Effluent Monitoring Plan for the 222-S Laboratory

International Nuclear Information System (INIS)

Robinson, A.V.

1991-11-01

A facility effluent monitoring plan is required by the US Department of Energy in DOE Order 5400.1 for any operations that involve hazardous materials and radioactive substances that could impact employee or public safety or the environment. This document is prepared using the specific guidelines identified in A Guide for Preparing Hanford Site Facility Effluent Monitoring Plans, WHC-EP-0438. This facility effluent monitoring plan assesses effluent monitoring systems against applicable federal, state, and local requirements. This facility effluent monitoring plan is the first annual report. It shall ensure long-range integrity of the effluent monitoring systems by requiring an update whenever a new process or operation introduces new hazardous materials or significant radioactive materials. The current operation of the 222-S facilities includes the provision of analytical and radiological chemistry services in support of Hanford Site processing plants. The emphasis is on waste management, chemical processing, environmental monitoring effluent programs at B Plant, the Uranium Oxide Plant, Tank Farms, the 242-A Evaporator, the Waste Encapsulation and Storage Facility, the Plutonium-Uranium Extraction Facility, the Plutonium Finishing Plant, process development/impact activities, and essential materials. The laboratory also supplies analytical services in support of ongoing waste tank characterization

Key projects to be enforced during the 11th Five-year Plan

Institute of Scientific and Technical Information of China (English)

无

2009-01-01

@@ Addressing major S&T issues of strategic importance to China's socioeconomic growth, national security and development sustainability, the key projects of CAS during the period of the 11th Five-year Plan (2006-2010) are large-scale research initiatives with an expectation to give rise to S&T breakthroughs.

Worldwide Emerging Environmental Issues Affecting the U.S. Military. November 2006 Report

Science.gov (United States)

2006-11-01

agricultural and industrial demands, falling water tables, and changes in glacial and snow-cap melting patterns. On November 20, Beijing’s air...efficient communication of biomonitoring studies’ results; and a review of the bioethical issues concerning biomonitoring, including confidentiality and

The Korean Study of Women’s Health-Related Issues (K-Stori: Rationale and Study Design

Directory of Open Access Journals (Sweden)

Ha Na Cho

2017-06-01

Full Text Available Abstract Background Measures to address gender-specific health issues are essential due to fundamental, biological differences between the sexes. Studies have increasingly stressed the importance of customizing approaches directed at women’s health issues according to stages in the female life cycle. In Korea, however, gender-specific studies on issues affecting Korean women in relation to stages in their life cycle are lacking. Accordingly, the Korean Study of Women’s Health-Related Issues (K-Stori was designed to investigate life cycle-specific health issues among women, covering health status, awareness, and risk perceptions. Methods K-Stori was conducted as a nationwide cross-sectional survey targeting Korean women aged 14–79 years. Per each stage in the female life cycle (adolescence, childbearing age, pregnancy & postpartum, menopause, and older adult stage, 3000 women (total 15,000 were recruited by stratified multistage random sampling for geographic area based on the 2010 Resident Registration Population in Korea. Specialized questionnaires per each stage (total of five were developed in consultation with multidisciplinary experts and by reflecting upon current interests into health among the general population of women in Korea. This survey was conducted from April 1 to June 31, 2016, at which time investigators from a professional research agency went door-to-door to recruit residents and conducted in-person interviews. Discussion The study’s findings may help with elucidating health issues and unmet needs specific to each stage in the life cycle of Korean women that have yet to be identified in present surveys.

Brain MRI and SPECT in the diagnosis of early neurological involvement in Wilson's disease

Energy Technology Data Exchange (ETDEWEB)

Piga, Mario; Satta, Loredana; Serra, Alessandra; Loi, Gianluigi [Policlinico Universitario, University of Cagliari, Nuclear Medicine, Department of Medical Science, Monserrato, Cagliari (Italy); Murru, Alessandra; Demelia, Luigi [Policlinico Universitario, University of Cagliari, Gastroenterology, Department of Medical Science, Monserrato, Cagliari (Italy); Sias, Alessandro [Policlinico Universitario, University of Cagliari, Radiology, Department of Medical Science, Monserrato, Cagliari (Italy); Marrosu, Francesco [Policlinico Universitario, University of Cagliari, Neurology, Department of Medical Science, Monserrato, Cagliari (Italy)

2008-04-15

To evaluate the impact of brain MRI and single-photon emission computed tomography (SPECT) in early detection of central nervous system abnormalities in patients affected by Wilson's disease (WD) with or without neurological involvement. Out of 25 consecutive WD patients, 13 showed hepatic involvement, ten hepatic and neurological manifestations, and twp hepatic, neurological, and psychiatric symptoms, including mainly movement disorders, major depression, and psychosis. Twenty-four healthy, age-gender matched subjects served as controls. All patients underwent brain MRI and {sup 99m}Tc-ethyl-cysteinate dimer (ECD) SPECT before starting specific therapy. Voxel-by-voxel analyses were performed using statistical parametric mapping to compare differences in {sup 99m}Tc-ECD brain uptake between the two groups. Brain MRI showed T2-weighted hyperintensities in seven patients (28%), six of whom were affected by hepatic and neurological forms. Brain perfusion SPECT showed pathological data in 19 patients (76%), revealing diffuse or focal hypoperfusion in superior frontal (Brodmann area (BA) 6), prefrontal (BA 9), parietal (BA 40), and occipital (BA 18, BA 39) cortices in temporal gyri (BA 37, BA 21) and in caudatus and putamen. Moreover, hepatic involvement was detected in nine subjects; eight presented both hepatic and neurological signs, while two exhibited WD-correlated hepatic, neurological, and psychiatric alterations. All but one patient with abnormal MRI matched with abnormal ECD SPECT. Pathologic MRI findings were obtained in six out of ten patients with hepatic and neurological involvement while abnormal ECD SPECT was revealed in eight patients. Both patients with hepatic, neurological, and psychiatric involvement displayed abnormal ECD SPECT and one displayed an altered MRI. These findings suggest that ECD SPECT might be useful in detecting early brain damage in WD, not only in the perspective of assessing and treating motor impairment but also in evaluating

Forest planning at territory level: a methodological proposal

Directory of Open Access Journals (Sweden)

Agnoloni S

2009-05-01

Full Text Available This paper describes goals and methodologies of the Land Plan for Forest and Natural Environment Management Guidance (PFTI stemming from the Ri.Selv.Italia national project (within the “Forest Land Planning” 4.2 subproject. The PFTI geographic range of application is at an intermediate level between single forest-management-unit-level plan and regional forest plans, and deals with forest and pastures resources management. PFTI’s main purposes concern forest resource and forest economy analysis and assessment of the benefits that can be provided to local population through a rational forest management, taking into account also the social structure and potential local conflicts. PFTI’s final task is then to weigh up all these issues in order to give specific participated forest management guidelines at a territorial scale. Unlike the forest-management-unit-level plan, whose specific duties are predetermined and fixed, the PFTI is not necessarily a mandatory plan. On the opposite, PFTI should suggest several specific silviculture guidelines and alternative management scenarios.

An Analysis of Policy Issues in Natural Gas Industry Restructuring

Energy Technology Data Exchange (ETDEWEB)

Seo, J.K. [Korea Energy Economics Institute, Euiwang (Korea)

2001-12-01

This report explores controversial issues and problems that could emerge in the process of implementing the government's restructuring plan for natural gas industry and aims to suggest policy directions regarding the restructuring. To begin with, it examines current conditions surrounding natural gas industry including domestic demand and supply conditions, world LNG market trend, structural changes of the industry in OECD countries, possibilities of introducing effective competition and assignment of existing import contracts. In doing so, we probe whether the direction of the natural gas industry restructuring is proper and suggest that the results be reflected when a more detailed restructuring implementation plan is formulated. Also, this report suggests possible schemes related to major institutional changes expected by the basic restructuring plan and the detailed restructuring implementation plan announced by the government. First, it presents several alternative ways to properly divide up the import/wholesales section of Korea Gas Corporation. Second, it examines critical issues such as the method of using gas supply facilities and gas balancing mechanism, and presents adoptable alternatives for each issue. These issues constitute the core of network and market operation rules which need to be in place when adopting an open access system, which in turn is a prerequisite for sales competition. Third, the report examines price systems, including gas commodity pricing and rate-making design for transportation service, by first anticipating the direction of changes in gas rate regulation. Specifically, it presents possible ways to design the service rate for each function of pipeline network and import terminals, and discusses controversial issues in determining total cost-of-service and allocating the cost-of-service to each functional service offered such as distance-related rates, interruptible service rate. Lastly, in relation to the opening of retail

Technology for Democracy in Smart City Planning

Directory of Open Access Journals (Sweden)

Paolo De Pascali

2014-02-01

Full Text Available In recent history the relationship between technology and urban planning has been variously taken into account (and possibly also undervalued, but lately it has come into focus with the maturation ofthe concept of the Smart City. Building on an analysis of documents dealing with the issue andcurrent experiences, this paper tries to determine which opportunity factors the new technologies are offering for the improvement of urban planning. In particular it considers how these technologies arebeing integrated into the processes of participatory planning thus supporting the development of direct democracy. The resulting complex framework suggests four main fields of application where the new technologies can contribute to addressing contents and governance of the plan for an urban organisation that enhances virtuous behaviours and steers the town’s residents towardsadopting them.

China Naval Modernization: Implications for U.S. Navy Capabilities -- Background and Issues for Congress

Science.gov (United States)

2008-09-12

1995 the Spanish shipbuilder Empresa Nacional Bazan (now Navantia) offered to build for the PLAN a low-cost, lightweight conventional-takeoff-and...in one of China’s premier naval journals.172 These same observers stated that: Chinese researchers display intimate familiarity with all U.S. Navy

Subglotic Stenosis as manifestation in Wegener’s Disease. A case report

Directory of Open Access Journals (Sweden)

Sofía VALLE-OLSEN

2017-03-01

Full Text Available Introduction and objective: Subglottic stenosis in Wegener’s disease (WD represents a diagnostic challenge because it’s ability to be the unique manifestation. Description: A case of subglottic GW described in a woman 14 years. Discussion: Subglottic stenosis secondary to Wegener’s disease use to be associated with ENT symptoms, so these can give us the etiological suspicion. In the absence of these, we should include it in the differential diagnosis and try a histopathologic confirmation. Conclusions: In an isolated subglottic stenosis, rule Wegener's disease performing a biopsy of nasal mucosa and two serology tests.

Community development planning

International Nuclear Information System (INIS)

Gray, S.I.

1983-01-01

The focus of this paper will be methods of local community involvement in the community development planning efforts which will be required at the recommended sites. Community development planning will include capital improvement plans, housing plans, zoning changes, business development plans and other community service and fiscal plans required to meet the projected needs of new residents as a result of the repository construction and operation. This paper will present, (1) the need for community planning, (2) methods of responding to community planning needs, (3) current community planning issues to be addressed. 2 references, 1 figure

2727-S Nonradioactive Dangerous Waste Storage Facility Closure Plan

International Nuclear Information System (INIS)

Wilczek, T.A.; Laws, J.R.; Izatt, R.D.

1992-01-01

This closure plan describes the activities for final closure of the 2727-S Nonradioactive Dangerous Waste Storage (NRDWS) Facility at the Hanford Site. The 2727-S NRDWS Facility provided container storage for nonradioactive dangerous and extremely hazardous wastes generated in the research and development laboratories, process operations, and maintenance and transportation functions throughout the Hanford Site. Storage operations began at the 2727-S NRDWS Facility March 14, 1983, and continued until December 30, 1986, when the last shipment of materials from the facility took place. These storage operations have been moved to the new 616 NRDWS Facility, which is an interim status unit located between the 200 East and 200 West Areas of the Hanford Site

Challenges and Approaches in River Delta Planning - report on training workshop

NARCIS (Netherlands)

Wosten, J.H.M.; Douven, W.; Long Phi, H.; Fida Abdullah Khan, M.

2012-01-01

River delta’s, like the Mekong Delta (Vietnam), Ganges-Brahmaputra Delta (Bangladesh), Irrawady (Myanmar) and Ciliwung Delta (Indonesia) are developing rapidly and characterized by large-scale urbanization and industrialization processes. They are facing serious planning challenges related to issues

Editorial: AABFJ Volume 8, Issue 4 Special Issue in Financial Markets and Financial Instruments

Directory of Open Access Journals (Sweden)

Ciorstan Smark

2014-10-01

Full Text Available Financial planning in Australia is in a time of change and challenge. Educational standards and regulation are in flux. There is a strong need to move financial planning into a more esteemed professional position as financial planners are not always considered the safest source of advice for people in Asia and the pacific rim when it comes to investing their much needed retirement funds. This Special Issue on Financial Planning and Financial Instruments brings together articles from financial planning, banking, financial markets and retirement policy.

Strategic Program Planning Lessons Learned in Developing the LTS S&T Roadmap

Energy Technology Data Exchange (ETDEWEB)

Duane Hanson; Brent Dixon; Gretchen Matthern

2003-07-01

Technology roadmapping is a strategic planning method used by companies to identify and plan the development of technologies necessary for new products. The U.S. Department of Energy’s Office of Environmental Management has used this same method to refine requirements and identify knowledge and tools needed for completion of defined missions. This paper describes the process of applying roadmapping to clarify mission requirements and identify enhancing technologies for the Long-Term Stewardship (LTS) of polluted sites after site cleanup has been completed. The nature of some contamination problems is such that full cleanup is not achievable with current technologies and some residual hazards remain. LTS maintains engineered contaminant barriers and land use restriction controls, and monitors residual contaminants until they no longer pose a risk to the public or the environment. Roadmapping was used to clarify the breadth of the LTS mission, to identify capability enhancements needed to improve mission effectiveness and efficiency, and to chart out the research and development efforts to provide those enhancements. This paper is a case study of the application of roadmapping for program planning and technical risk management. Differences between the planned and actual application of the roadmapping process are presented along with lessons learned. Both the process used and lessons learned should be of interest for anyone contemplating a similar technology based planning effort.

Exploring the relationship between planning and procurement in Western U.S. electric utilities

Energy Technology Data Exchange (ETDEWEB)

Carvallo Bodelon, Juan Pablo [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Energy Analysis and Environmental Impacts Division; Sanstad, Alan H. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Energy Analysis and Environmental Impacts Division; Larsen, Peter H. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Energy Analysis and Environmental Impacts Division

2017-06-01

Integrated resource planning (IRP) is an important regulatory process used in many U.S. states to formulate and evaluate least-cost and risk-assessed portfolios to meet future load requirements for electric utilities. In principle, effective implementation of IRP seeks to assure regulators and the public that utility investment decisions, given uncertainty, are as cost-effective as possible. However, to date, there is no empirical assessment on the effectiveness of IRP implementation. In this analysis, we compare planning, procurement processes and actual decisions for a sample of twelve load serving entities (LSEs) across the Western U. S. from 2003-2014. The 2008/2009 recession provides a unique “stress test” to the planning process and offers an excellent opportunity to trace how procurement decisions responded to this largely unforeseen event. In aggregate, there is a general alignment between planned and procured supply-side capacity. However, there are significant differences in the choice of supply-side resources and type of ownership for individual LSEs. We develop case studies for three LSEs and find that subsequent plans differ significantly due to changes in the planning environment and that procurement decisions in some cases are impacted by factors that are not accounted for in the planning process. Our results reveal that a limited amount of information produced during the long-term planning process (e.g., forecasts, methods, and least cost/risk portfolios) are ultimately used during the procurement process, and that the latter process relies extensively on the most recent information available for decision making. These findings suggest that states' IRP rules and regulations mandating long-term planning horizons with the same analytical complexity throughout the planning period may not create useful information for the procurement process. The social value of a long-term planning process that departs from procurement and the balance between

Planning, Promoting and Passing School Tax Issues. [Revised Edition].

Science.gov (United States)

Whitman, Robert L.; Pittner, Nicholas A.

This book provides Ohio citizens with information on school tax issues and levy campaigning. The material is presented in a structural step-by-step process that lends itself to the practical application for preparing a levy. This book is a guide to understanding various tax issues, tax reduction factors, and the changing tax duplicate that affects…

Highlights of the new U.S. Energy Policy Plan

International Nuclear Information System (INIS)

Rusche, B.C.

1982-01-01

This paper gives the highlights of the New U.S. Energy Policy Plan, a reformulation of policies affecting energy, as part of President Reagan's comprehensive Program for Economic Recovery. A survey is given of the different energy sources and their importances now and in the future along with a definition of the government's and the private sector's roles in energy production. (orig.)

Evacuation planning for Lilco's Shoreham plant

International Nuclear Information System (INIS)

Zorpette, G.

1987-01-01

This article reports that the Shoreham Nuclear Power Station, an 820-megawatt boiling-water reactor built by the Long Island Lighting Co., has taken 19 years to build and has so far cost nearly $5 billion. Because no emergency plan for coping with a major accident has been approved by the U.S. Nuclear Regulatory Commission, the plant has not been issued a Federal license to operate at full power. The cause of this impasse is the refusal of New York State and Suffolk County to participate in any emergency plan, on the ground that the geography of Long Island would make such a plan impossible to execute. The regulatory commission's rules require the operator of a nuclear plant to enlist cooperation from state and local authorities in an emergency plan. Shoreham's supporters charge that state and county are exploiting that requirement to block operation of the politically unpopular plant

The 13 february action plan and the prospects for the North Korean nuclear issue

International Nuclear Information System (INIS)

Narushige, Muchishita

2007-01-01

parties made minimum necessary concessions, and gained minimum satisfactory outcome. For example, North Korea succeeded in bringing the United States back on the engagement track, but it had to freeze the important part of its nuclear facilities and be satisfied with 50,000 tons of HFO, a tenth of the amount that North Korea received annually under the 1994 Agreed Framework. The United States had North Korea committed to the freeze of its nuclear facility again at the price far cheaper than in 1994, but had to soften its North Korea policy at the risk of appearing to give in to North Korea's brinkmanship diplomacy and reward its 'bad behavior', or nuclear test more specifically. China and South Korea successfully persuaded the United States to go back on the engagement track. But to compensate for the U.S. concession, China had to provide strong political leadership, and South Korea had to bear the financial cost involved in implementing the Action Plan. Japan got upset about the shift in the U.S. position since the policy change left Japan alone on the containment track. However, it was not such a bad deal for Japan to be able to have North Korea's nuclear facilities frozen without making substantial financial contributions as it did under the Agreed Framework. The U.S. policy toward North Korea seems to have been significantly affected by the developments in Iraq and Iran. The United States has decided to increase its commitment, particularly military commitment, to the situations in these countries, and the decision made it necessary for it to reduce its commitment to North Korea. Given the high priorities put on Iraq and Iran, North Korea policy was relatively expendable for the United States. This assessment might sound somewhat puzzling because the United States has become more engaged with North Korea diplomatically. However, it was the reduction in U.S. policy commitment to North Korea in the sense that the United States no longer aims at regime change, which

The Challenges of Implementing Sustainable Development: The Case of Sofia’s Master Plan

Directory of Open Access Journals (Sweden)

Aleksandar D. Slaev

2016-12-01

Full Text Available In this paper, we explore how master planning promotes and implements particular urban development patterns and, more generally, contributes to sustainability. Our goal is to understand the link between urban growth intentions articulated through the master planning process and realisation of its specific forms, e.g., monocentric or polycentric, compact or dispersed. As a case study, we examine the current General Urban Development Plan (GUDP of the Bulgarian capital Sofia against the city’s actual development pattern. We observe that the primary goals of the GUDP are to promote a polycentric urban structure and low-density expansion, as well as preserve green edges. While the question of whether and how these goals reflect the sustainability ideal requires further consideration, there are some indications that Sofia’s GUDP may not be effective in encouraging sustainable forms of growth. Substantial inconsistencies exist between the plan’s overall goals and some of its measures and implementation tools. The results on the ground suggest that, despite the plan’s low-density aspirations, Sofia is becoming more compact and densified, while losing its green edges and failing to redirect growth to its northern territories where ample space and opportunities exist. We conclude that employing the achievements of research on sustainability and developing relevant implementation tools such as more effective zoning regulations and viable suburban transportation infrastructure are necessary for realising both the patterns proposed through master planning and achieving sustainable urban growth.

Wave-equation dispersion inversion of surface waves recorded on irregular topography

KAUST Repository

Li, Jing; Schuster, Gerard T.; Lin, Fan-Chi; Alam, Amir

2017-01-01

Significant topographic variations will strongly influence the amplitudes and phases of propagating surface waves. Such effects should be taken into account, otherwise the S-velocity model inverted from the Rayleigh dispersion curves will contain significant inaccuracies. We now show that the recently developed wave-equation dispersion inversion (WD) method naturally takes into account the effects of topography to give accurate S-velocity tomograms. Application of topographic WD to demonstrates that WD can accurately invert dispersion curves from seismic data recorded over variable topography. We also apply this method to field data recorded on the crest of mountainous terrain and find with higher resolution than the standard WD tomogram.

Wave-equation dispersion inversion of surface waves recorded on irregular topography

KAUST Repository

Li, Jing

2017-08-17

Significant topographic variations will strongly influence the amplitudes and phases of propagating surface waves. Such effects should be taken into account, otherwise the S-velocity model inverted from the Rayleigh dispersion curves will contain significant inaccuracies. We now show that the recently developed wave-equation dispersion inversion (WD) method naturally takes into account the effects of topography to give accurate S-velocity tomograms. Application of topographic WD to demonstrates that WD can accurately invert dispersion curves from seismic data recorded over variable topography. We also apply this method to field data recorded on the crest of mountainous terrain and find with higher resolution than the standard WD tomogram.

Recent NRC research activities addressing valve and pump issues

Energy Technology Data Exchange (ETDEWEB)

Morrison, D.L.

1996-12-01

The mission of the U.S. Nuclear Regulatory Commission (NRC) is to ensure the safe design, construction, and operation of commercial nuclear power plants and other facilities in the U.S.A. One of the main roles that the Office of Nuclear Regulatory Research (RES) plays in achieving the NRC mission is to plan, recommend, and implement research programs that address safety and technical issues deemed important by the NRC. The results of the research activities provide the bases for developing NRC positions or decisions on these issues. Also, RES performs confirmatory research for developing the basis to evaluate industry responses and positions on various regulatory requirements. This presentation summarizes some recent RES supported research activities that have addressed safety and technical issues related to valves and pumps. These activities include the efforts on determining valve and motor-operator responses under dynamic loads and pressure locking events, evaluation of monitoring equipment, and methods for detecting and trending aging of check valves and pumps. The role that RES is expected to play in future years to fulfill the NRC mission is also discussed.

Save with Solar newsletter, Spring 2000 Issue, Vol. 3, No. 1

Energy Technology Data Exchange (ETDEWEB)

NONE

2000-04-21

This is the first issue of the third volume (Spring 2000) of a technical bulletin produced for the Department of Energy's (DOE's) Federal Energy Management Program (FEMP). It is intended for Federal solar energy champions; that is, energy officers, contracting officials, facility managers, and others who plan or work on projects in which solar and other renewable energy technologies are installed in Federal government facilities, per the directives of Executive Order 13123 and the President's Million Solar Roofs Initiative. This issue contains an article about a new initiative led by DOE and the Department of the Interior/National Park Service; it involves obtaining more renewable energy systems for the national parks. Another article describes projects adding solar and wind systems to government facilities serving Native Americans, and there are other news items as well.

Research plan for lands administered by the U.S. Department of the Interior in the Interior Columbia Basin and Snake River Plateau

Science.gov (United States)

Beever, Erik A.; Pyke, David A.

2002-01-01

This document presents a long-term research strategy designed to address current and future research needs for management of Department of the Interior-administered ecosystems in the Intermountain West. Although the research plan was developed in the context of the Interior Columbia Basin Ecosystem Management Project, the plan addresses many high-priority issues facing land managers throughout the Intermountain West. These issues pose management challenges that may be addressed with applied research both currently and in upcoming decades. Possessing a particular focus on semiarid ecosystems, the plan is a collection of research questions under five categories of research emphases: 1) restoration; 2) rangeland health; 3) aquatic-terrestrial connections; 4) development of monitoring and evaluation protocols; and 5) species and habitats at risk.

Penobscot Indian Nation's Strategic Energy Planning Efficiency on tribal Lands

Energy Technology Data Exchange (ETDEWEB)

Sockalexis, Mike; Fields, Brenda

2006-11-30

The energy grant provided the resources to evaluate the wind, hydro, biomass, geothermal and solar resource potential on all Penobscot Indian Naiton's Tribal lands. The two objectives address potential renewable energy resources available on tribal lands and energy efficiency measures to be taken after comprehensive energy audits of commercial facilities. Also, a Long Term Strategic Energy Plan was developed along with a plan to reduce high energy costs.

NNSA?s Computing Strategy, Acquisition Plan, and Basis for Computing Time Allocation

Energy Technology Data Exchange (ETDEWEB)

Nikkel, D J

2009-07-21

This report is in response to the Omnibus Appropriations Act, 2009 (H.R. 1105; Public Law 111-8) in its funding of the National Nuclear Security Administration's (NNSA) Advanced Simulation and Computing (ASC) Program. This bill called for a report on ASC's plans for computing and platform acquisition strategy in support of stockpile stewardship. Computer simulation is essential to the stewardship of the nation's nuclear stockpile. Annual certification of the country's stockpile systems, Significant Finding Investigations (SFIs), and execution of Life Extension Programs (LEPs) are dependent on simulations employing the advanced ASC tools developed over the past decade plus; indeed, without these tools, certification would not be possible without a return to nuclear testing. ASC is an integrated program involving investments in computer hardware (platforms and computing centers), software environments, integrated design codes and physical models for these codes, and validation methodologies. The significant progress ASC has made in the past derives from its focus on mission and from its strategy of balancing support across the key investment areas necessary for success. All these investment areas must be sustained for ASC to adequately support current stockpile stewardship mission needs and to meet ever more difficult challenges as the weapons continue to age or undergo refurbishment. The appropriations bill called for this report to address three specific issues, which are responded to briefly here but are expanded upon in the subsequent document: (1) Identify how computing capability at each of the labs will specifically contribute to stockpile stewardship goals, and on what basis computing time will be allocated to achieve the goal of a balanced program among the labs. (2) Explain the NNSA's acquisition strategy for capacity and capability of machines at each of the labs and how it will fit within the existing budget constraints. (3

Hanford Waste Vitrification Plant Technology Plan

International Nuclear Information System (INIS)

Sexton, R.A.

1988-06-01

The reference Hanford plan for disposal of defense high-level waste is based on waste immobilization in glass by the vitrification process and temporary vitrified waste storage at the Hanford Site until final disposal in a geologic repository. A companion document to the Hanford Waste Management Plan (HWMP) is the Draft, Interim Hanford Waste Management Technology Plan (HWMTP), which provides a description of the technology that must be developed to meet the reference waste management plan. One of the issues in the HWMTP is DST-6, Immobilization (Glass). The HWMTP includes all expense funding needed to complete the Hanford Waste Vitrification Plant (HWVP) project. A preliminary HWVP Technology Plan was prepared in 1985 as a supporting document to the HWMTP to provide a more detailed description of the technology needed to construct and operate a vitrification facility. The plan was updated and issued in 1986, and revised in 1987. This document is an annual update of the plan. The HWVP Technology Plan is limited in scope to technology that requires development or confirmation testing. Other expense-funded activities are not included. The relationship between the HWVP Technology Plan and other waste management issues addressed in the HWMTP is described in section 1.6 of this plan. 6 refs., 4 figs., 34 tabs

Issues of governance in water resource management and spatial planning

NARCIS (Netherlands)

Rocco de Campos Pereira, R.C.; Schweitzer, R.

2013-01-01

This paper describes governance arrangements in regional spatial planning and water resources management at the regional level from a normative point of view. It discusses the need to integrate spatial planning and resources management in order to deliver socially sustainable integral territorial

Experimental investigations on the fluid flow through a wall subchannel of a rod bundle (P/D = 1.036, W/D = 1.072)

International Nuclear Information System (INIS)

Rehme, K.

1982-07-01

Measurements of the distributions of the mean velocity, the wall shear stresses and the turbulence were performed in a wall subchannel of a rod bundle of four parallel rods arranged symmetrically in a rectangular channel (P/D = 1.036, W/D = 1.072). The Reynolds number of this investigation was Re = 7.60 x 10 4 . The experimental results show that the momentum transport is highly anisotropic especially in the gaps of the rod bundle. Influences of secondary flow cannot be detected in the distribution of the time-mean velocity, however, such influences are found in the distributions of the turbulence intensities and the kinetic energy of turbulence. Very high turbulence intensities were observed in the gap between the rods. The comparison between experimental wall shear stress distributions and those calculated with the VELASCO-code shows discrepancies especially in the gap between the rods. (orig.) [de

Planning for Integrated Transport in Indonesia: Some Lessons from the UK’s Experience

Directory of Open Access Journals (Sweden)

Yos Sunitiyoso

2012-01-01

Full Text Available Traffic congestion has been a major problem in many cities in Indonesia, thus requiring abetter transport policy. Many developed countries, including the United Kingdom, has beenimplementing the integrated transport policy to replace traditional transport policy that focuson only building roads to anticipate traffic demand. This paper provides a highlight on theimplementation of integrated transport policy in the United Kingdom. Some key issues thatcan be learnt by the Indonesian government from their experience are discussed. This includesthe integration within and between all types of transport, integration with land use planning,integration with environment policy and integration with policies for education, health andwealth creations. In the implementation, the policy requires continuity and stability inorganization and politics, coordination in local transport plans, more devolution on powerand revenue funding from the government in addition to capital funding.Key words: traffic congestion, integrated transport policy

Groundwater Protection Program Management Plan For The U.S. Department Of Energy Y-12 National Security Complex, Oak Ridge, Tennessee

Energy Technology Data Exchange (ETDEWEB)

Elvado Environmental, LLC

2009-09-01

This document presents the Groundwater Protection Program (GWPP) management plan for the U.S. Department of Energy (DOE) Y-12 National Security Complex (hereafter referenced as Y-12). The Y-12 GWPP functions as the primary point-of-contact for groundwater-related issues at Y-12, provides stewardship of the extensive network of groundwater monitoring wells at Y-12, and serves as a resource for technical expertise, support, and historical data for groundwater-related activities at Y-12. These organizational functions each serve the primary programmatic purpose of the GWPP, which is to ensure that groundwater monitoring activities within areas under Y-12 administrative control provide representative data in compliance with the multiple purposes of applicable state and federal regulations, DOE orders, and the corporate policies of Babcock & Wilcox Technical Services Y-12 LLC (hereafter referenced as B&W Y-12), the Y-12 management and operations (M&O) contractor for DOE. B&W Y-12 is a new corporate name, assumed in January 2007, for the company formerly known as BWXT Y-12, L.L.C., hereafter referenced as BWXT. This GWPP management plan addresses the requirements of DOE Order 450.1A Environmental Protection Program (hereafter referenced as DOE O 450.1A), which emphasize a site-wide approach for groundwater protection at each DOE facility through implementation of groundwater surveillance monitoring. Additionally, this plan addresses the relevant and applicable GWPP elements and goals described in the DOE O 450.1A technical guidance documents issued in June 2004 (DOE 2004) and May 2005 (DOE 2005). This GWPP management plan is a 'living' document that is reviewed annually, revised and reissued every three years, and is formatted to provide for updating individual sections independent of the rest of the document. Section 2 includes a short description of the groundwater system at Y-12, the history of groundwater monitoring at Y-12 and the corresponding evolution of the GWPP

Animal Experimentation: Issues for the 1980s.

Science.gov (United States)

Zola, Judith C.; And Others

1984-01-01

Examines the extent to which issues related to animal experimentation are in conflict and proposes choices that might least comprise them. These issues include animal well-being, human well-being, self-interest of science, scientific validity and responsibility, progress in biomedical and behavioral science, and the future quality of medical care.…

Trends in Technology Planning and Funding in Florida K-12 Public Schools

Directory of Open Access Journals (Sweden)

ALBERT DIETER RITZHAUPT

2008-12-01

Full Text Available This empirical research investigates trends in technology planning and funding in Florida’s K–12 public schools between the 2003–04 and 2005–06 academic years. Survey items that focused on funding and planning issues on Florida’s statewide school technology integration survey were analyzed using logistic models. Results indicate a significant increase in the number of schools revising their technology plans on a regular basis; a significant increase in the frequency with which Florida’s K–12 public schools are seeking funding for technology-related initiatives; a significant increase in parent, administrator, teacher, and student involvement in the technology planning process; and a significant decline in adequate funding for software and hardware needs. In addition, schools with low proportions of economically disadvantaged students sought and were awarded significantly more funds from donations and federal and state grants. Implications for educational leadership and policy are provided.

Research on evacuation planning as nuclear emergency preparedness

International Nuclear Information System (INIS)

Yamamoto, Kazuya

2007-10-01

The International Atomic Energy Agency (IAEA) has introduced new concepts of precautionary action zone (PAZ) and urgent protective action planning zone (UPZ) in 'Preparedness and Response for a Nuclear or Radiological Emergency' (GS-R-2 (2002)), in order to reduce substantially the risk of severe deterministic health effects. Open literature based research was made to reveal problems on evacuation planning and the preparedness for nuclear emergency arising from introduction of PAZ into Japan that has applied the emergency planning zone (EPZ) concept currently. In regard to application of PAZ, it should be noted that the requirements for preparedness and response for a nuclear or radiological emergency are not only dimensional but also timely. The principal issue is implementation of evacuation of precautionary decided area within several hours. The logic of evacuation planning for a nuclear emergency and the methods of advance public education and information in the U.S. is effective for even prompt evacuation to the outside of the EPZ. As concerns evacuation planning for a nuclear emergency in Japan, several important issues to be considered were found, that is, selection of public reception centers which are outside area of the EPZ, an unique reception center assigned to each emergency response planning area, public education and information of practical details about the evacuation plan in advance, and necessity of the evacuation time estimates. To establish a practical evacuation planning guide for nuclear emergencies, further researches on application of traffic simulation technology to evacuation time estimates and on knowledge of actual evacuation experience in natural disasters and chemical plant accidents are required. (author)

Stormwater Pollution Prevention Plan for the TA-03-38 Carpenter's Shop, Los Alamos National Laboratory, Revision 3, January 2018

Energy Technology Data Exchange (ETDEWEB)

Burgin, Jillian Elizabeth [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

2018-02-01

This Storm Water Pollution Prevention Plan (SWPPP) was developed in accordance with the provisions of the Clean Water Act (33 U.S.C. §§1251 et seq., as amended), and the Multi-Sector General Permit for Storm Water Discharges Associated with Industrial Activity (U.S. EPA, June 2015) issued by the U.S. Environmental Protection Agency (EPA) for the National Pollutant Discharge Elimination System (NPDES) and using the industry specific permit requirements for Sector A–Timber Products, Subsector A4 (Wood Products Facilities not elsewhere classified) as a guide. This SWPPP applies to discharges of stormwater from the operational areas of the TA-03-38 Carpenter’s Shop at Los Alamos National Laboratory. Los Alamos National Laboratory (also referred to as LANL or the “Laboratory”) is owned by the Department of Energy (DOE), and is operated by Los Alamos National Security, LLC (LANS). Throughout this document, the term “facility” refers to the TA-03-38 Carpenter’s Shop and associated areas. The current permit expires at midnight on June 4, 2020.

Idaho National Engineering Laboratory site development plan

International Nuclear Information System (INIS)

1994-09-01

This plan briefly describes the 20-year outlook for the Idaho National Engineering Laboratory (INEL). Missions, workloads, worker populations, facilities, land, and other resources necessary to fulfill the 20-year site development vision for the INEL are addressed. In addition, the plan examines factors that could enhance or deter new or expanded missions at the INEL. And finally, the plan discusses specific site development issues facing the INEL, possible solutions, resources required to resolve these issues, and the anticipated impacts if these issues remain unresolved

Results of the Workshop on Two-Phase Flow, Fluid Stability and Dynamics: Issues in Power, Propulsion, and Advanced Life Support Systems

Science.gov (United States)

McQuillen, John; Rame, Enrique; Kassemi, Mohammad; Singh, Bhim; Motil, Brian

2003-01-01

The Two-phase Flow, Fluid Stability and Dynamics Workshop was held on May 15, 2003 in Cleveland, Ohio to define a coherent scientific research plan and roadmap that addresses the multiphase fluid problems associated with NASA s technology development program. The workshop participants, from academia, industry and government, prioritized various multiphase issues and generated a research plan and roadmap to resolve them. This report presents a prioritization of the various multiphase flow and fluid stability phenomena related primarily to power, propulsion, fluid and thermal management and advanced life support; and a plan to address these issues in a logical and timely fashion using analysis, ground-based and space-flight experiments.

Regional analysis of S emission-deposition trends in North America from 1979 through 1988

International Nuclear Information System (INIS)

Shannon, J.D.

1991-01-01

Variations in SO x emissions weighted by a regional deposition model are shown to account for most of the variance in regionally averaged annual wet deposition (WD) and precipitation-weighted concentrations (PWCs) of sulfate in the United States and Canada during the period 1979--1988. Total emissions decreased about 15% during that time. For all sites combined, weighted emissions accounted for about two-thirds of the variance, with slightly better performance for PWC than for WD. Restricting the emission regions to the states containing the monitoring sites in each region led to very mixed results, with good explanation of WD and PWC variance in the Midwest and in all sites combined but generally poor explanation elsewhere, particularly for WD. In some regions, local emission densities are quite low, and most deposition would be expected to result from outside sources, so no strong relationship between local emission rates and deposition would be expected. Including annual meteorological variability in the emission weighting improved variance explanation in several of the peripheral regions, but reduced variance explanation elsewhere, particularly in the Midwest, the region of the highest emission density. 10 refs., 2 figs., 1 tab

Strategic Sustainability Performance Plan. Discovering Sustainable Solutions to Power and Secure America’s Future

Energy Technology Data Exchange (ETDEWEB)

None, None

2010-09-01

Sustainability is fundamental to the Department of Energy’s research mission and operations as reflected in the Department’s Strategic Plan. Our overarching mission is to discover the solutions to power and secure America’s future.

The Back Office of School Reform: Educational Planning Units in German-Speaking Switzerland (1960s and 1970s)

Science.gov (United States)

Bosche, Anne

2016-01-01

The present article investigates what consequences for educational policy and/or educational administration were drawn from the upheavals of the 1960s and 1970s. A popular diagnosis in political science is that political decision-makers were pushed into a "reactive" role. In the context of a general "planning euphoria", and an…

75 FR 27141 - Group Health Plans and Health Insurance Issuers Providing Dependent Coverage of Children to Age...

Science.gov (United States)

2010-05-13

... Group Health Plans and Health Insurance Issuers Providing Dependent Coverage of Children to Age 26 Under... Information and Insurance Oversight of the U.S. Department of Health and Human Services are issuing substantially similar interim final regulations with respect to group health plans and health insurance coverage...

75 FR 41787 - Requirement for Group Health Plans and Health Insurance Issuers To Provide Coverage of Preventive...

Science.gov (United States)

2010-07-19

... Requirement for Group Health Plans and Health Insurance Issuers To Provide Coverage of Preventive Services... Insurance Oversight of the U.S. Department of Health and Human Services are issuing substantially similar interim final regulations with respect to group health plans and health insurance coverage offered in...

U.S. Support of Plan Colombia: Rethinking the Ends and Means

National Research Council Canada - National Science Library

Flynn, Stephen

2001-01-01

Dr. Stephen Flynn argues that the U.S. emphasis on drug control in its support of Plan Colombia is misguided and akin to prescribing an antibiotic regime to combat a disease not caused by bacteria or similar micro-organisms...

Clinical Use of Next-Generation Sequencing in the Diagnosis of Wilson’s Disease

Directory of Open Access Journals (Sweden)

Dániel Németh

2016-01-01

Full Text Available Objective. Wilson’s disease is a disorder of copper metabolism which is fatal without treatment. The great number of disease-causing ATP7B gene mutations and the variable clinical presentation of WD may cause a real diagnostic challenge. The emergence of next-generation sequencing provides a time-saving, cost-effective method for full sequencing of the whole ATP7B gene compared to the traditional Sanger sequencing. This is the first report on the clinical use of NGS to examine ATP7B gene. Materials and Methods. We used Ion Torrent Personal Genome Machine in four heterozygous patients for the identification of the other mutations and also in two patients with no known mutation. One patient with acute on chronic liver failure was a candidate for acute liver transplantation. The results were validated by Sanger sequencing. Results. In each case, the diagnosis of Wilson’s disease was confirmed by identifying the mutations in both alleles within 48 hours. One novel mutation (p.Ala1270Ile was found beyond the eight other known ones. The rapid detection of the mutations made possible the prompt diagnosis of WD in a patient with acute liver failure. Conclusions. According to our results we found next-generation sequencing a very useful, reliable, time-saving, and cost-effective method for diagnosing Wilson’s disease in selected cases.

Launching and implementing FEMP`s 1997 outreach plan featuring the ``You Have the Power`` campaign

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-11-01

The Federal Energy Management Program`s (FEMP`s) mission is to help Federal agencies reduce energy costs by delivering effective technology transfer and outreach programs. It is important that FEMP provide leadership and good examples to the Federal sector so that FEMP`s programs and priorities can be transferred throughout Federal agencies and offices across the Nation. In order to achieve this mission, FEMP must send a clear message to everyone involved with the management of Federal facilities concerning its available resources, effective information and assistance, educational programs, tools, and training. To achieve this objective, American Ideas and Designs, Inc., d/b/a Greening America (hereinafter referred to as Recipient) has assisted FEMP in developing a comprehensive energy efficiency technology transfer program plan (hereinafter referred to as the outreach plan). A key component of the outreach plan involved the development and launch of a technology transfer campaign entitled ``You Have the Power.`` The outreach plan and the ``You Have the Power`` campaign emphasized the ability of individual Federal employees, Federal agencies, and stakeholder organizations to easily access FEMP`s energy efficiency tools and resources through a set of integrated interagency delivery programs.

Performance-based ratemaking for electric utilities: Review of plans and analysis of economic and resource-planning issues. Volume 2, Appendices

Energy Technology Data Exchange (ETDEWEB)

Comnes, G.A.; Stoft, S.; Greene, N. [Lawrence Berkeley Lab., CA (United States); Hill, L.J. [Oak Ridge National Lab., TN (United States)

1995-11-01

This document contains summaries of the electric utilities performance-based rate plans for the following companies: Alabama Power Company; Central Maine Power Company; Consolidated Edison of New York; Mississippi Power Company; New York State Electric and Gas Corporation; Niagara Mohawk Power Corporation; PacifiCorp; Pacific Gas and Electric; Southern California Edison; San Diego Gas & Electric; and Tucson Electric Power. In addition, this document also contains information about LBNL`s Power Index and Incentive Properties of a Hybrid Cap and Long-Run Demand Elasticity.

Translating disaster resilience into spatial planning practice in South Africa: Challenges and champions

Directory of Open Access Journals (Sweden)

Willemien van Niekerk

2013-03-01

Full Text Available It is highly likely that hazards and extreme climatic events will occur more frequently in the future and will become more severe – increasing the vulnerability and risk of millions of poor urbanites in developing countries. Disaster resilience aims to reduce disaster losses by equipping cities to withstand, absorb, adapt to or recover from external shocks. This paper questions whether disaster resilience is likely to be taken up in spatial planning practices in South Africa, given its immediate developmental priorities and challenges. In South Africa, issues of development take precedence over issues of sustainability, environmental management and disaster reduction. This is illustrated by the priority given to ‘servicing’ settlements compared to the opportunities offered by ‘transforming’ spaces through post-apartheid spatial planning. The City of Durban’s quest in adapting to climate change demonstrates hypothetically that if disaster resilience were to be presented as an issue distinct from what urban planners are already doing, then planners would see it as insignificant as compared to addressing the many developmental backlogs and challenges. If, however, it is regarded as a means to secure a city’s development path whilst simultaneously addressing sustainability, then disaster resilience is more likely to be translated into spatial planning practices in South Africa.

Metro Vancouver air quality management plan : progress report

Energy Technology Data Exchange (ETDEWEB)

NONE

2008-10-15

The Greater Vancouver Regional District (GVRD) developed an air quality management plan (AQMP) in 2005 as a means of addressing air quality issues in the region. The plan required progress reports every 2 years as well as a comprehensive review every 5 years. The AQMP established goals to minimize risk to public health from air pollution, improve visibility, and minimize the region's contributions to global climatic change by reducing emissions; implementing local air quality management programs; and enhancing air quality information and public awareness. The AQMP also included a sustainability framework for GVRD's policies and regulations related to regional growth, service delivery and political leadership. Regional strategies for solid waste and liquid waste management were developed in 2008. The sustainability framework has developed 3 priority goals: (1) to reduce diesel particulates by 75 per cent from Metro Vancouver corporate sources by 2012, (2) to be carbon neutral by 2012 excluding solid waste operations, and (3) to reduce regional GHGs by 15 per cent by 2015, and 33 per cent by 2020. Progress updates on regional planning efforts for the AQMP were presented. The report also outlined trends and performance measures used by the GVRD, and discussed changes in air quality issues and priorities that have occurred since the AQMP was adopted in 2005. 1 tab., 8 figs.

U.S. Air Force Bomber Sustainment and Modernization: Background and Issues for Congress

Science.gov (United States)

2014-06-04

Rebalancing ” Toward Asia, coordinated by Mark E. Manyin. 5 For in-depth analysis of DOD’s new strategic guidance, see CRS Report R42146, In Brief...Pacific region as part of the Obama Administration’s rebalancing strategy. On multiple occasions, Deputy Secretary of Defense Ashton Carter has stated...modernization plan. The resulting B-1 SAIP provides detailed analysis and recommendations for the period 2014 to 2025 and presents optimum B-1 portfolios

Landscape ecological assessment: a tool for integrating biodiversity issues in strategic environmental assessment and planning.

Science.gov (United States)

Mörtberg, U M; Balfors, B; Knol, W C

2007-03-01

To achieve a sustainable development, impacts on biodiversity of urbanisation, new infrastructure projects and other land use changes must be considered on landscape and regional scales. This requires that important decisions are made after a systematic evaluation of environmental impacts. Landscape ecology can provide a conceptual framework for the assessment of consequences of long-term development processes like urbanisation on biodiversity components, and for evaluating and visualising the impacts of alternative planning scenarios. The aim of this paper was to develop methods for integrating biodiversity issues in planning and strategic environmental assessment in an urbanising environment, on landscape and regional levels. In order to test developed methods, a case study was conducted in the region of Stockholm, the capital of Sweden, and the study area embraced the city centre, suburbs and peri-urban areas. Focal species were tested as indicators of habitat quality, quantity and connectivity in the landscape. Predictive modelling of habitat distribution in geographic information systems involved the modelling of focal species occurrences based on empirical data, incorporated in a landscape ecological decision support system. When habitat models were retrieved, they were applied on future planning scenarios in order to predict and assess the impacts on focal species. The scenario involving a diffuse exploitation pattern had the greatest negative impacts on the habitat networks of focal species. The scenarios with concentrated exploitation also had negative impacts, although they were possible to mitigate quite easily. The predictions of the impacts on habitats networks of focal species made it possible to quantify, integrate and visualise the effects of urbanisation scenarios on aspects of biodiversity on a landscape level.

Waking and sleeping following water deprivation in the rat.

Directory of Open Access Journals (Sweden)

Davide Martelli

Full Text Available Wake-sleep (W-S states are affected by thermoregulation. In particular, REM sleep (REMS is reduced in homeotherms under a thermal load, due to an impairment of hypothalamic regulation of body temperature. The aim of this work was to assess whether osmoregulation, which is regulated at a hypothalamic level, but, unlike thermoregulation, is maintained across the different W-S states, could influence W-S occurrence. Sprague-Dawley rats, kept at an ambient temperature of 24°C and under a 12 h∶12 h light-dark cycle, were exposed to a prolonged osmotic challenge of three days of water deprivation (WD and two days of recovery in which free access to water was restored. Two sets of parameters were determined in order to assess: i the maintenance of osmotic homeostasis (water and food consumption; changes in body weight and fluid composition; ii the effects of the osmotic challenge on behavioral states (hypothalamic temperature (Thy, motor activity, and W-S states. The first set of parameters changed in WD as expected and control levels were restored on the second day of recovery, with the exception of urinary Ca(++ that almost disappeared in WD, and increased to a high level in recovery. As far as the second set is concerned, WD was characterized by the maintenance of the daily oscillation of Thy and by a decrease in activity during the dark periods. Changes in W-S states were small and mainly confined to the dark period: i REMS slightly decreased at the end of WD and increased in recovery; ii non-REM sleep (NREMS increased in both WD and recovery, but EEG delta power, a sign of NREMS intensity, decreased in WD and increased in recovery. Our data suggest that osmoregulation interferes with the regulation of W-S states to a much lesser extent than thermoregulation.

Monarto’s Contested Landscape

Directory of Open Access Journals (Sweden)

Paul Walker

2015-11-01

Full Text Available The proposal to develop a new city at Monarto in South Australia during the 1970s was an important project of the reforming government of Don Dunstan. Dunstan’s view was that Monarto would be a city environmentally suited to the tough conditions of its site, and to an ‘Australian way of life’. As planning and preliminary design proceeded from 1972 to 1975, the landscape potential of the city’s selected site became central to its conception. This paper draws on new research comprising interviews with key participants and archival material to examine four issues: the adoption of an environmental orientation in Australian urban planning and discourse in the 1970s; strategies in the design proposals that seemingly gave Monarto validity even as the demographic and political drivers for it dissolved away; the investigations that supported Monarto’s landscape strategies; and attitudes to social and cultural history that the Monarto project adopted. While ultimately the plan for Monarto was abandoned, the projected city’s landscape can be seen as a theatre for competing values in relation to natural and cultural heritage and design ambitions. The paper situates Monarto within national and international urban discourse that is more complex than has been previously acknowledged, indicative of competing values and ideologies in the planning, landscape and design discourses of the period.

A model for effective intergovernmental planning

International Nuclear Information System (INIS)

Moore, R.C.

1991-01-01

Effective intergovernmental planning processes are essential to the resolution of potential affects created by federal projects. Intergovernmental planning for the proposed Yucca Mountain High-level Nuclear Waste Repository has not been effective to date. In this paper, two successful planning efforts are described. The common elements of these processes are analyzed to provide a model that can be used for the resolution of impacts from other projects. Management authorities of the entities involved should establish a working group to conduct the intergovernmental planning. The parties must identify issues that can be resolved through intergovernmental planning. Clear management authority and direction to the staff participating the planning process is essential. Issues which cannot be resolved should not be included in the goals of the working group. Funding to support the planning process is essential

Nevada State plan; final approval determination. Occupational Safety and Health Administration (OSHA), U.S. Department of Labor. Final State plan approval--Nevada.

Science.gov (United States)

2000-04-18

This document amends OSHA's regulations to reflect the Assistant Secretary's decision granting final approval to the Nevada State plan. As a result of this affirmative determination under section 18(e) of the Occupational Safety and Health Act of 1970, Federal OSHA's standards and enforcement authority no longer apply to occupational safety and health issues covered by the Nevada plan, and authority for Federal concurrent jurisdiction is relinquished. Federal enforcement jurisdiction is retained over any private sector maritime employment, private sector employers on Indian land, and any contractors or subcontractors on any Federal establishment where the land is exclusive Federal jurisdiction. Federal jurisdiction remains in effect with respect to Federal government employers and employees. Federal OSHA will also retain authority for coverage of the United States Postal Service (USPS), including USPS employees, contract employees, and contractor-operated facilities engaged in USPS mail operations.

New model of enterprises resource planning implementation planning process in manufacturing enterprises

Directory of Open Access Journals (Sweden)

Mirjana Misita

2016-05-01

Full Text Available This article presents new model of enterprises resource planning implementation planning process in manufacturing enterprises based on assessment of risk sources. This assessment was performed by applying analytic hierarchy process. Analytic hierarchy process method allows variation of relative importance of specific risk sources dependent on the section from which the risk source originates (organizational environment, technical issues, people issues, adoption process management, and external support. Survey was conducted on 85 manufacturing enterprises involved with an enterprises resource planning solution. Ranking of risk sources assessments returns most frequent risks of enterprises resource planning implementation success in manufacturing enterprises, and representative factors were isolated through factor analysis by risk source origin. Finally, results indicate that there are hidden causes of failed implementation, for example, risk source “top management training and education,” from risk origin “adoption process management.”

Advanced Reactor Technologies - Regulatory Technology Development Plan (RTDP)

Energy Technology Data Exchange (ETDEWEB)

Moe, Wayne L. [Idaho National Lab. (INL), Idaho Falls, ID (United States)

2017-08-23

This DOE-NE Advanced Small Modular Reactor (AdvSMR) regulatory technology development plan (RTDP) will link critical DOE nuclear reactor technology development programs to important regulatory and policy-related issues likely to impact a “critical path” for establishing a viable commercial AdvSMR presence in the domestic energy market. Accordingly, the regulatory considerations that are set forth in the AdvSMR RTDP will not be limited to any one particular type or subset of advanced reactor technology(s) but rather broadly consider potential regulatory approaches and the licensing implications that accompany all DOE-sponsored research and technology development activity that deal with commercial non-light water reactors. However, it is also important to remember that certain “minimum” levels of design and safety approach knowledge concerning these technology(s) must be defined and available to an extent that supports appropriate pre-licensing regulatory analysis within the RTDP. Final resolution to advanced reactor licensing issues is most often predicated on the detailed design information and specific safety approach as documented in a facility license application and submitted for licensing review. Because the AdvSMR RTDP is focused on identifying and assessing the potential regulatory implications of DOE-sponsored reactor technology research very early in the pre-license application development phase, the information necessary to support a comprehensive regulatory analysis of a new reactor technology, and the resolution of resulting issues, will generally not be available. As such, the regulatory considerations documented in the RTDP should be considered an initial “first step” in the licensing process which will continue until a license is issued to build and operate the said nuclear facility. Because a facility license application relies heavily on the data and information generated by technology development studies, the anticipated regulatory

Advanced Reactor Technology -- Regulatory Technology Development Plan (RTDP)

Energy Technology Data Exchange (ETDEWEB)

Moe, Wayne Leland [Idaho National Lab. (INL), Idaho Falls, ID (United States)

2015-05-01

This DOE-NE Advanced Small Modular Reactor (AdvSMR) regulatory technology development plan (RTDP) will link critical DOE nuclear reactor technology development programs to important regulatory and policy-related issues likely to impact a “critical path” for establishing a viable commercial AdvSMR presence in the domestic energy market. Accordingly, the regulatory considerations that are set forth in the AdvSMR RTDP will not be limited to any one particular type or subset of advanced reactor technology(s) but rather broadly consider potential regulatory approaches and the licensing implications that accompany all DOE-sponsored research and technology development activity that deal with commercial non-light water reactors. However, it is also important to remember that certain “minimum” levels of design and safety approach knowledge concerning these technology(s) must be defined and available to an extent that supports appropriate pre-licensing regulatory analysis within the RTDP. Final resolution to advanced reactor licensing issues is most often predicated on the detailed design information and specific safety approach as documented in a facility license application and submitted for licensing review. Because the AdvSMR RTDP is focused on identifying and assessing the potential regulatory implications of DOE-sponsored reactor technology research very early in the pre-license application development phase, the information necessary to support a comprehensive regulatory analysis of a new reactor technology, and the resolution of resulting issues, will generally not be available. As such, the regulatory considerations documented in the RTDP should be considered an initial “first step” in the licensing process which will continue until a license is issued to build and operate the said nuclear facility. Because a facility license application relies heavily on the data and information generated by technology development studies, the anticipated regulatory

'From Man to Bacteria': W.D. Hamilton, the theory of inclusive fitness, and the post-war social order.

Science.gov (United States)

Swenson, Sarah A

2015-02-01

W.D. Hamilton's theory of inclusive fitness aimed to define the evolved limits of altruism with mathematical precision. Although it was meant to apply universally, it has been almost irretrievably entwined with the particular case of social insects that featured in his famous 1964 papers. The assumption that social insects were central to Hamilton's early work contradicts material in his rich personal archive. In fact, careful study of Hamilton's notes, letters, diaries, and early essays indicates the extent to which he had humans in mind when he decided altruism was a topic worthy of biological inquiry. For this reason, this article reconsiders the role of extra-scientific factors in Hamilton's early theorizing. In doing so, it offers an alternative perspective as to why Hamilton saw self-sacrifice to be an important subject. Although the traditional narrative prioritizes his distaste for benefit-of-the-species explanations as a motivating factor behind his foundational work, I argue that greater attention ought to be given to Hamilton's hope that science could be used to address social ills. By reconsidering the meaning Hamilton intended inclusive fitness to have, we see that while he was no political ideologue, the socio-political relevance of his theory was nevertheless integral to its development. Copyright © 2015 Elsevier Ltd. All rights reserved.

City planning in Yugoslavia in the 20th century: The case study of Belgrade

Directory of Open Access Journals (Sweden)

Bajić-Brković Milica V.

2002-01-01

Full Text Available The long term planning in Yugoslavia is usually associated with early 1930s and with issuing of the Building Code in 1931, which represented the first official document legally regulating planning and construction of cities and towns. The term planning in its nowadays meaning has first appeared only after the Second World War. In 1949 the Act on General Urban Plan (GUP was issued and according to many authors that was a crucial point that marked the very beginning of the long term planning in Yugoslavia. Since then its development has been characterized by numerous changes resulting from the political, economic and social modifications and tendencies, as well as influences from other environments and disciplines. Finally, in the mid-1960s a paradigm of GUP was established, which despite several modifications regarding some methodological and procedural questions, has remained unchanged up to our day. The General Urban Planning in Yugoslavia has developed in a paradigm manner, in Kuhn’s sense of meaning. In this paper this fifty year process has been explored and discussed. Kuhn’s views and theory on the structure of scientific revolution have provided the conceptual background for it, and helped in guiding analysis of the phenomena as well as in explaining certain phases or particular facets within each of them. The General Urban Planning has undergone the whole process of a paradigm change but with a specific pace of progress, with some of the phases being very long and others being exceedingly short. In this paper this process has been reviewed and development of the GUP model presented and discussed. To illustrate the point the case study of the city of Belgrade has been drawn.

Support of Publication Costs, Atlantic Meridional Overturning Circulation Special Issue of Deep Sea Research II Journal

Energy Technology Data Exchange (ETDEWEB)

Amy Honchar

2012-11-12

The contribution of funds from DOE supported publication costs of a special issue of Deep Sea Research arising from presentations at the First U.S. Atlantic Meridional Overturning Circulation (AMOC) Meeting held 4-6 May, 2009 to review the US implementation plan and its coordination with other monitoring activities. The special issue includes a total of 16 papers, including publications from three DOE-supported investigators (ie Sevellec, F., and A.V. Fedorov; Hu et. al., and Wan et. al.,). The special issue addresses DOE interests in understanding and simulation/modeling of abrupt climate change.

Transit's leading edge : innovations in service and technology : issue paper 7

Energy Technology Data Exchange (ETDEWEB)

NONE

2003-11-01

The Canadian Urban Transit Association is committed to raising awareness of the social, environmental and economic benefits of mass transit systems. Innovation is needed to address the challenges of attracting new riders, resolving fiscal imbalances, and meeting environmental concerns. This issue paper presents examples of how Canada's transit industry has used innovation to address the issue of climate change and fight smog. It includes a brief description of some of the ways that Canadian transit suppliers and transit systems are going green: Canada's bus builders are developing hybrid buses; Grand River Transit is improving air quality with clean diesel; Montreal's Transit Society is reducing emissions with biodiesel buses; Saskatoon Transit Service is using biodiesel buses; Laval's Transit Society is listening to customer complaints in an effort to reduce response times and improve customer service; Canadian Urban Transit Association is improving customer service; Transit Windsor is promoting a smog solution; Winnipeg Transit is working with employers to boost ridership; Trapeze Software Group is providing customers with quick and accurate trip itineraries; St. John's Transportation Commission has added solar-powered, light emitting diode illumination to bus stops; the City of Ottawa has an established transit priority measures; and, Infodev EDI Inc. has supplied automated high-technology solutions for passenger counting and vehicle location tracking to several Canadian transit systems. refs., figs.

Development Planning & Policies under Mahalanobis Strategy: A Tale of India’s Dilemma

Directory of Open Access Journals (Sweden)

Dr. Asim K. Karmakar

2013-07-01

In the above backdrop the present paper gives a short review of Mahalanobis strategy of development planning in the context of the then India’s dilemma: dynamic industrialization and static agriculture.

Proposed plan for the K-Area Bingham Pump Outage Pit (643-1G)

International Nuclear Information System (INIS)

Palmer, E.

1997-06-01

This Proposed Plan is issued by the U.S. Department of Energy (DOE), which functions as the lead agency for SRS remedial activities, and with concurrence by the U.S. Environmental Protection Agency (EPA) and the South Carolina Department of Health and Environmental Control (SCDHEC). The purpose of this Proposed Plan is to describe the preferred remedial alternative for addressing the K-Area Bingham Pump Outage Pit (643-1G) (K BPOP) located at the Savannah River Site (SRS) in Aiken, South Carolina and to solicit public comments on the preferred alternative

Planning for gasification of cellulosic wastes: Issues, feasibility and case study

International Nuclear Information System (INIS)

Staniewski, M.E.

1993-01-01

Gasification is presented as a concept that can assist municipalities and private companies to reduce the amount of solid waste generated and to utilize the cellulosic fraction of such waste as a biofuel. The technical and economic feasibility of cellulosic waste gasification is examined along with the implications associated with the environmental, social, and regulatory issues within a planning context. Study methods included a literature review, survey research employing nonstructured interviews, and a case study analysis. Opportunities for gasification are focused on regional governments in Ontario. The case study concentrated on the Regional Municipality of Waterloo. Regional governments in Ontario can benefit from utilizing the gasification concept to achieve a substantial reduction in the waste stream in an environmentally sound manner and contribute to solving worldwide problems associated with fossil fuel utilization. However, provincial and public acceptance will affect regional government decisions regarding gasification. Separate legislation should be enacted distinguishing gasification from incineration. In addition, the effectiveness of the environmental approval process must be improved; present procedures consume excess time and resources and act to discourage the involvement of public and private proponents. Public acceptance is likely to be affected by negative experiences associated with solid waste combustion. Nonbiased, reliable information is needed to clarify doubts and stress gasification's potential benefits. 85 refs., 15 figs., 26 tabs

The U.S. National Action Plan to Improve Health Literacy: A Model for Positive Organizational Change.

Science.gov (United States)

Baur, Cynthia; Harris, Linda; Squire, Elizabeth

2017-01-01

This chapter presents the U.S. National Action Plan to Improve Health Literacy and its unique contribution to public health and health care in the U.S. The chapter details what the National Action Plan is, how it evolved, and how it has influenced priorities for health literacy improvement work. Examples of how the National Action Plan fills policy and research gaps in health care and public health are included. The first part of the chapter lays the foundation for the development of the National Action Plan, and the second part discusses how it can stimulate positive organizational change to help create health literate organizations and move the nation towards a health literate society.

Energy investments and environmental implications: key policy issues in developing countries

Energy Technology Data Exchange (ETDEWEB)

Siddayao, Corazon M. (World Bank Washington, DC (USA). Economic Development Institute)

1992-03-15

Energy investments imply changes in the physical, social, and economic environment. Hence, both the short-term and the long-term costs and benefits of these investments must be taken into account. These changes may affect not only the immediate environment of the investment site but may extend geographically far beyond national borders as well as beyond the lifetimes of the people for whom the investments are intended. This paper reviews the issues relevant to developing countries. General conceptual and policies issues are discussed. Issues about the measurement of costs and benefits (including issues of 'sustainability' and the internalization of externalities resulting from environmental changes) as well as the role of opportunity costs in deciding a country's energy investment strategies are raised. The macroeconomic and institutional issues relevant to environmental impacts that might be incorporated in energy planning are suggested. The paper is based on a presentation to the 'Workshop on energy investments and the environment'. 24 refs., 1 fig.

Mexico's Regulatory Engagement in Bulk Electric Power System Planning: An Overview of U.S. Practices and Tools

Energy Technology Data Exchange (ETDEWEB)

O' Neill, Barbara; Hurlbut, David; Pena, Ivonne; Gagne, Douglas; Cook, Jeff; Bracho, Ricardo

2016-06-01

Mexico's transition to a modern wholesale power market will place new demands on how regulators evaluate and approve transmission expansion projects. Transmission projects in a modern wholesale market fulfill one of several needs, and utilities, regional transmission organizations, and regulatory authorities in the United States have encountered comparable challenges in their market transitions to ensure projects meeting each type of need can be built. The purpose of this report is to open a window to view that experience. The report examines key practices of different U.S. jurisdictions that have moved from transmission planning to transmission approval, and it focuses on the role of the regulator in supporting a planning process that equitably meets identified needs.

Planned place of birth

DEFF Research Database (Denmark)

Overgaard, Charlotte; Coxon, Kirstie; Stewart, Mary

Title Planned place of birth: issues of choice, access and equity. Outline In Northern European countries, giving birth is generally safe for healthy women with uncomplicated pregnancies, and their babies. However, place of birth can affect women’s outcomes and experiences of birth. Whilst tertiary...... countries, maternity care is provided free to women, through public financing of health care; universal access to care is therefore secured. Nevertheless, different models of care exist, and debates about the appropriateness of providing maternity care in different settings take place in both countries...... in Denmark Coxon K et al: Planned place of birth in England: perceptions of accessing obstetric units, midwife led units and home birth amongst women and their partners. How these papers interrelate These papers draw upon recent research in maternity care, undertaken in Denmark and in England. In both...

An analysis of operational experience during low power and shutdown and a plan for addressing human reliability assessment issues

International Nuclear Information System (INIS)

Barriere, M.; Luckas, W.; Whitehead, D.; Ramey-Smith, A.

1994-06-01

Recent nuclear power plant events (e.g. Chernobyl, Diablo Canyon, and Vogtle) and US Nuclear Regulatory Commission (NRC) reports (e.g. NUREG-1449) have led to concerns regarding human reliability during low power and shutdown (LP ampersand S) conditions and limitations of human reliability analysis (HRA) methodologies in adequately representing the LP ampersand S environment. As a result of these concerns, the NRC initiated two parallel research projects to assess the influence of LP ampersand S conditions on human reliability through an analysis of operational experience at pressurized water reactors (PWRs) an boiling water reactors (BWRs). These research projects, performed by Brookhaven National Laboratory for PWRS, and Sandia National Laboratories for BWRs, identified unique aspects of human performance during LP ampersand S conditions and provided a program plan for research and development necessary to improve existing HRA methodologies. This report documents the results of the analysis of LP ampersand S operating experience and describes the improved HRA program plan

Report of the AAPM Task Group No. 105: Issues associated with clinical implementation of Monte Carlo-based photon and electron external beam treatment planning

International Nuclear Information System (INIS)

Chetty, Indrin J.; Curran, Bruce; Cygler, Joanna E.; DeMarco, John J.; Ezzell, Gary; Faddegon, Bruce A.; Kawrakow, Iwan; Keall, Paul J.; Liu, Helen; Ma, C.-M. Charlie; Rogers, D. W. O.; Seuntjens, Jan; Sheikh-Bagheri, Daryoush; Siebers, Jeffrey V.

2007-01-01

The Monte Carlo (MC) method has been shown through many research studies to calculate accurate dose distributions for clinical radiotherapy, particularly in heterogeneous patient tissues where the effects of electron transport cannot be accurately handled with conventional, deterministic dose algorithms. Despite its proven accuracy and the potential for improved dose distributions to influence treatment outcomes, the long calculation times previously associated with MC simulation rendered this method impractical for routine clinical treatment planning. However, the development of faster codes optimized for radiotherapy calculations and improvements in computer processor technology have substantially reduced calculation times to, in some instances, within minutes on a single processor. These advances have motivated several major treatment planning system vendors to embark upon the path of MC techniques. Several commercial vendors have already released or are currently in the process of releasing MC algorithms for photon and/or electron beam treatment planning. Consequently, the accessibility and use of MC treatment planning algorithms may well become widespread in the radiotherapy community. With MC simulation, dose is computed stochastically using first principles; this method is therefore quite different from conventional dose algorithms. Issues such as statistical uncertainties, the use of variance reduction techniques, the ability to account for geometric details in the accelerator treatment head simulation, and other features, are all unique components of a MC treatment planning algorithm. Successful implementation by the clinical physicist of such a system will require an understanding of the basic principles of MC techniques. The purpose of this report, while providing education and review on the use of MC simulation in radiotherapy planning, is to set out, for both users and developers, the salient issues associated with clinical implementation and

Nordic nuclear safety research program 1994-1997. Project coordination incl. SAM-4 general information issues. Report 1996. Plans for 1997

International Nuclear Information System (INIS)

1997-04-01

NKS (Nordic Nuclear Safety Research) is a cooperative body in nuclear safety, radiation protection and emergency preparedness. Its purpose is to carry out cost-effective Nordic projects, thus producing research results, exercises, information, recommendations, manuals etc., to be used by decision makers and other concerned staff members at authorities and within the nuclear industry. This is the annual report for 1996, the third year of the fifth four-year NKS program (1994-1997). The report also contains plans for the rest of the program period, including budget proposals. The following major fields of research have been identified: reactor safety; radioactive waste; radioecology; emergency preparedness; and information issues. A total of nine projects are now under way within that framework. One project (RAK-1) is dedicated to reactor safety strategies: how to avoid serious accidents. A parallel project (RAK-2) deals with minimizing releases in case of an accident. When can an overheated reactor core still be water-cooled? What might be the consequences of the cooling? All Nordic countries have long-lived low and medium level radioactive waste that requires final disposal. One project (AFA-1) addresses that issue. Environmental impact of radioactive releases is studied in two radioecology projects. The project on marine radioecology, including sediment research (EKO-1), encompasses sampling, analysis and modeling. These are also key issues in the project on long ecological half-lives in semi-natural systems (EKO-2). The transfer of radioactive cesium and strontium in the chains soil - vegetation - sheep and mushroom - roe deer is studied, along with freshwater systems. Long-term doses to main is the ultimate output from the obtained models. Another aspect of environmental impact is emergency preparedness. A recently started project, EKO-5, addresses the issue of early planning for cleanup operations following a fallout. 'Early' in this context means within the

Wilson's disease: two treatment modalities. Correlations to pretreatment and posttreatment brain MRI

Energy Technology Data Exchange (ETDEWEB)

Leiros da Costa, Maria do Desterro [Federal University of Paraiba, Movement Disorders Unit, Paraiba (Brazil); Spitz, Mariana; Bacheschi, Luiz Alberto; Barbosa, Egberto Reis [University of Sao Paulo, Movement Disorders Unit, Sao Paulo (Brazil); Leite, Claudia Costa; Lucato, Leandro Tavares [University of Sao Paulo, Department of Radiology, Sao Paulo (Brazil)

2009-10-15

Brain magnetic resonance imaging (MRI) studies on Wilson's disease (WD) show lack of correlations between neurological and neuroimaging features. Long-term follow-up reports with sequential brain MRI in patients with neurological WD comparing different modalities of treatment are scarce. Eighteen patients with neurological WD underwent pretreatment and posttreatment brain MRI scans to evaluate the range of abnormalities and the evolution along these different periods. All patients underwent at least two MRI scans at different intervals, up to 11 years after the beginning of treatment. MRI findings were correlated with clinical picture, clinical severity, duration of neurological symptoms, and treatment with two different drugs. Patients were divided into two groups according to treatment: d-penicillamine (D-P), zinc (Zn), and Zn after the onset of severe intolerance to D-P. MRI scans before treatment showed, in all patients, hypersignal intensity lesions on T2- and proton-density-weighted images bilaterally and symmetrically at basal nuclei, thalamus, brain stem, cerebellum, brain cortex, and brain white matter. The most common neurological symptoms were: dysarthria, parkinsonism, dystonia, tremor, psychiatric disturbances, dysphagia, risus sardonicus, ataxia, chorea, and athetosis. From the neurological point of view, there was no difference on the evolution between the group treated exclusively with D-P and the one treated with Zn. Analysis of MRI scans with longer intervals after the beginning of treatment depicted a trend for neuroimaging worsening, without neurological correspondence, among patients treated with Zn. Neuroimaging pattern of evolution was more favorable for the group that received exclusively D-P. (orig.)

The nuclear emergency plans

International Nuclear Information System (INIS)

Fuertes Menendez, M. J.; Gasco Leonarte, L.; Granada Ferrero, M. J.

2007-01-01

Planning of the response to emergencies in nuclear plants is regulated by the Basic Nuclear Emergency Plan (PLABEN). This basic Plan is the guidelines for drawing up, implementing and maintaining the effectiveness of the nuclear power plant exterior nuclear emergency plans. The five exterior emergency plans approved as per PLABEN (PENGUA, PENCA, PENBU, PENTA and PENVA) place special emphasis on the preventive issues of emergency planning, such as implementation of advance information programs to the population, as well as on training exercises and drills. (Author)

Interim Hanford Waste Management Technology Plan

International Nuclear Information System (INIS)

1985-09-01

The Interim Hanford Waste Management Technology Plan (HWMTP) is a companion document to the Interim Hanford Waste Management Plan (HWMP). A reference plan for management and disposal of all existing and certain projected future radioactive Hanford Site Defense Wastes (HSDW) is described and discussed in the HWMP. Implementation of the reference plan requires that various open technical issues be satisfactorily resolved. The principal purpose of the HWMTP is to present detailed descriptions of the technology which must be developed to close each of the technical issues associated with the reference plan identified in the HWMP. If alternative plans are followed, however, technology development efforts including costs and schedules must be changed accordingly. Technical issues addressed in the HWMTP and HWMP are those which relate to disposal of single-shell tank wastes, contaminated soil sites, solid waste burial sites, double-shell tank wastes, encapsulated 137 CsCl and 90 SrF 2 , stored and new solid transuranic (TRU) wastes, and miscellaneous wastes such as contaminated sodium metal. Among the high priority issues to be resolved are characterization of various wastes including early determination of the TRU content of future cladding removal wastes; completion of development of vitrification (Hanford Waste Vitrification Plant) and grout technology; control of subsidence in buried waste sites; and development of criteria and standards including performance assessments of systems proposed for disposal of HSDW. Estimates of the technology costs shown in this report are made on the basis that all identified tasks for all issues associated with the reference disposal plan must be performed. Elimination of, consolidation of, or reduction in the scope of individual tasks will, of course, be reflected in corresponding reduction of overall technology costs

Moving ERP Systems to the Cloud - Data Security Issues

OpenAIRE

Pablo Saa; Andrés Cueva Costales; Oswaldo Moscoso-Zea; Sergio Lujan-Mora

2017-01-01

This paper brings to light data security issues and concerns for organizations by moving their Enterprise Resource Planning (ERP) systems to the cloud. Cloud computing has become the new trend of how organizations conduct business and has enabled them to innovate and compete in a dynamic environment through new and innovative business models. The growing popularity and success of the cloud has led to the emergence of cloud-based Software-as-a-Service (SaaS) ERP systems, a new alternative appr...

Carlsbad Area Office strategic plan

International Nuclear Information System (INIS)

1995-10-01

This edition of the Carlsbad Area Office Strategic Plan captures the U.S. Department of Energy's new focus, and supercedes the edition issued previously in 1995. This revision reflects a revised strategy designed to demonstrate compliance with environmental regulations earlier than the previous course of action; and a focus on the selected combination of scientific investigations, engineered alternatives, and waste acceptance criteria for supporting the compliance applications. An overview of operations and historical aspects of the Waste Isolation Pilot Plant near Carlsbad, New Mexico is presented

Lidar Remote Sensing for Characterizing Forest Vegetation - Special Issue. Foreword

Science.gov (United States)

Popescu, Sorin C.; Nelson, Ross F.

2011-01-01

The Silvilaser 2009 conference held in College Station, Texas, USA, was the ninth conference in the Silvilaser series, which started in 2002 with the international workshop on using lidar (Light Detection and Ranging) for analyzing forest structure, held in Victoria, British Columbia, Canada. Following the Canadian workshop, subsequent forestry-lidar conferences took place in Australia, Sweden, Germany, USA, Japan, Finland, and the United Kingdom (UK). By the time this Silvilaser 2009 special issue of PE&RS is published, the 10th international conference will have been held in Freiburg, Germany, and planning will be ongoing for the 11th meeting to take place in Tasmania, Australia, in October 2011. Papers presented at the 2005 conference held in Blacksburg, Virginia, USA, were assembled in a special issue of PE&RS published in December 2006. Other special issues resulting from previous conferences were published in journals such as the Canadian Journal of Remote Sensing (2003), the Scandinavian Journal of Forest Research (2004), and Japan s Journal of Forest Planning (2008). Given the conference history and the much longer record of publications on lidar applications for estimating forest biophysical parameters, which dates back to the early 1980s, we may consider lidar an established remote sensing technology for characterizing forest canopy structure and estimating forest biophysical parameters. Randy Wynne, a professor at Virginia Tech and the final keynote speaker at Silvilaser 2009, made the case that it was time to push 30 years of research into operations, along the lines of what has already been done to good effect in the Scandinavian countries. In Randy s words, it s time to "Just do it!" This special issue includes a selection of papers presented during the 2009 Silvilaser conference, which consisted of eight sections as follows: (1) biomass and carbon stock estimates, (2) tree species and forest type classification, (3) data fusion and integration, (4, 5

THE EFFECT OF A SUPEROUTBURST ON THE WHITE DWARF AND DISK OF VW HYDRI AS OBSERVED WITH FUSE

International Nuclear Information System (INIS)

Long, Knox S.; Gaensicke, Boris T.; Knigge, Christian; Froning, Cynthia S.; Monard, Berto

2009-01-01

We have used Far Ultraviolet Spectroscopic Explorer (FUSE) to obtain a series of 13 observations of the nearby dwarf nova VW Hyi that cover the period from the end of a superoutburst through the following normal outburst of the system. Here, we present the quiescent spectra taken after each outburst event. The spectra obtained during quiescence contain at least three components. The dominant component over most of the FUSE wavelength range is the white dwarf (WD), which cools following the superoutburst. The amount of cooling is dependent on the WD models utilized. For log g of 8.0, the temperature drops from 24,000 K just after the outburst to 20,000 K just before the normal outburst. For this model, and for a distance of 65 pc, the radius of the WD is approximately 8 x 10 8 cm and v sin(i) is ∼420 km s -1 . The fact that the derived radius is smaller than expected for a WD with log g = 8 suggests a higher gravity WD or that VW Hyi is somewhat further than its canonical distance of 65 pc. Either is possible given the current uncertainty (±20 pc) in the distance to VW Hyi. Earlier suggestions that the WD photosphere show evidence of CNO processed material are confirmed, but our analysis also highlights the fact that significant issues remain in terms of analyzing the spectra of WDs in such unusual physical situations. The second component is relatively featureless and shows substantial modulation on the orbital (and just after outburst, the superhump) period. The second component is most likely associated with the hot spot where material from the secondary encounters the disk, rather than emission from the boundary layer region between the inner disk and WD. This second component fades about 10 days after the superoutburst. There is also a third component, clearly visible in terms of broad emission lines of C III λ977, N III λ991, and a combination of Lyβ and O VI λλ1032, 1038, which appears to be accompanied by a flat continuum. The strength of the

Workforce and planning issues for the profession of periodontics in Australia and New Zealand.

Science.gov (United States)

Brown, Louise; Seymour, Gregory; Holborow, Douglas

2002-10-01

The speciality of periodontics in Australia and New Zealand has seen steady growth since 1986, when the Australian and New Zealand Academy of Periodontics (ANZAP) was formed. Very few members of ANZAP have retired in the 16 years since its formation. However, the results of a survey of members revealed that one-third of members plan to retire within the next 10 years, and over 50% of members will have retired within 15 years. The survey also revealed that most members were heavily booked, and nearly half were concerned by their level of busyness. A total of 22 members are currently seeking to employ a periodontist in their practice, and yet only three students will complete the MDSc program in periodontics in Australia at the end of this year. This paper presents the results of the ANZAP survey of members and addresses issues affecting the training of periodontists in Australia and New Zealand.

Ethical, legal and social issues in the context of the planning stages of the Southern African Human Genome Programme.

Science.gov (United States)

de Vries, Jantina; Slabbert, Melodie; Pepper, Michael S

2012-03-01

As the focus on the origin of modern man appears to be moving from eastern to southern Africa, it is recognised that indigenous populations in southern Africa may be the most genetically diverse on the planet and hence a valuable resource for human genetic diversity studies. In order to build regional capacity for the generation, analysis and application of genomic data, the Southern African Human Genome Programme was recently launched with the aid of seed funding from the national Department of Science and Technology in South Africa. The purpose of the article is to investigate pertinent ethical, legal and social issues that have emerged during the planning stages of the Southern African Human Genome Programme. A careful consideration of key issues such as public perception of genomic research, issues relating to genetic and genomic discrimination and stigmatisation, informed consent, privacy and data protection, and the concept of genomic sovereignty, is of paramount importance in the early stages of the Programme. This article will also consider the present legal framework governing genomic research in South Africa and will conclude with proposals regarding such a framework for the future.

Cross-border issues that arise in conjunction with the execution of U.S.-Canadian natural gas contracts

International Nuclear Information System (INIS)

Martin, J. G.

1999-01-01

Development of the U.S.-Canadian natural gas market as it is today and the issues that may arise in cross-border transactions involving natural gas contracts between the two countries are reviewed. In this context, the paper reviews recent history of U.S.-Canadian trade relations culminating in the development of NAFTA, the U.S. regulatory and legislative framework surrounding cross-border natural gas transactions, and general U.S. foreign trade policy that may come into play at the U.S.- Canada border. The paper also examines certain issues arising in the U.S. commercial context that may be of interest to Canadian corporations, specifically the U.S. Uniform Commercial Code, state jurisdiction on the U.S. side of the border, state and federal tax concerns, and the mechanics and potential benefits for a Canadian parent company in forming a U.S.-based subsidiary to handle U.S.-Canada natural gas transactions. 71 refs

Effective energy planning for improving the enterprise’s energy performance

Directory of Open Access Journals (Sweden)

Păunescu Carmen

2016-09-01

Full Text Available The global pressing need to protect the environment, save energy and reduce greenhouse gas emissions worldwide has prompted the enterprises to implementing both individual energy saving measures and a more systematic approach to improve the overall enterprise’s energy performance. Energy management is becoming a priority as enterprises strive to reduce energy costs, conform to regulatory requirements, and improve their corporate image. As such, enterprises are encouraged to manage their energy related matters in a systematic manner and a more harmonized way, to ensure continual improvement on their energy efficiency. Despite the increasing interest in energy management standards, a gap persists between energy management literature and current implementation practices. The release of the ISO 50001 international standard was meant to help the organizations develop sound energy management systems and effective process-based energy management structures that could be recognized through third-party certification. Building on the energy management literature and energy management standards, the current paper presents the essential steps the enterprises should take to practically design a sustainable energy management system. Also, by using multiple case studies of enterprises that have implemented an ISO 50001 energy management system, it introduces a structured approach that companies can use to effectively develop their energy planning and improve energy performance. The key components of the enterprise’s energy planning are discussed, as well as practical examples of energy objectives and performance indicators from various industries are offered. The paper shows that by establishing an effective energy planning system, this will efficiently meet demands for achieving energy performance indicators and international certification.

Planning and urbanistic projects – the non-author approach and issues of synergy in cooperation

Directory of Open Access Journals (Sweden)

Liljana Jankovič Grobelšek

2005-01-01

Full Text Available The article presents the non-author approach to urbanistic and planning projects. The project leader guides the entire project team, yet particular coordinators are also important. Contrary to authorship in architectural projects, in physical planning authorship is often or even always completely shared. Not only because planning projects can change significantly during adoption procedures, but mainly because there are many participating actors (designers, planners, commissioners and/or investors etc. that are involved in any project’s undertaking. Experience proves that the non-author approach is beneficial for good project management and creation of conditions for constructive cooperation within an interdisciplinary working group and with all the other contributing parties. Two tested examples are presented. Their comparison is very interesting, since the first example shows a project where good cooperation between the client, investor and designers, as well as willing interested public, conditioned quality improvements, while the second (because of the public and consequently against its interests diminished its quality significantly. Our judgement is that the quantity of the often mentioned necessity of public involvement is actually sufficient. There are no obstacles for public participation in urbanistic and physical planning, as long as the public is interested. Troubles are often triggered elsewhere – how to safeguard the common, public interest before particular publics (e.g. neighbours, the immediately affected etc..

THE CORRELATION BETWEEN STRATEGIC PLANNING AND ECONOMIC MOROCCAN SME’s PERFORMANCE

Directory of Open Access Journals (Sweden)

Hassan ABBAR

2016-11-01

Full Text Available Among management activities, the strategic function retains increasingly attention of authors being interested in SME's (small and medium-sized enterprise performance. Indeed, there are many authors who think that by following a strategy building formal process, SMEs can increase chances of success, while others consider that by trusting their manager’s intuition, SMEs can stimulate creativity and develop important competitive advantages at the same time. Further to these controversies, we aim through this communication to partake in this debate mattering to both researchers and managers by revising the relation between strategic planning and SMEs' economic performance. So as to handle this matter, we verify nearby 100 Moroccan SMEs, the degree of importance they grant to strategic planning. We also examine how SMEs strategic planning may or not be associated with their economic performance as measured by average variation sales over the last three years.

The treatment of Parkinson′s disease with deep brain stimulation: current issues

Directory of Open Access Journals (Sweden)

Alexia-Sabine Moldovan

2015-01-01

Full Text Available Deep brain stimulation has become a well-established symptomatic treatment for Parkinson′s disease during the last 25 years. Besides improving motor symptoms and long-term motor complications, positive effects on patients′ mobility, activities of daily living, emotional well-being and health-related quality of life have been recognized. Apart from that, numerous clinical trials analyzed effects on non-motor symptoms and side effects of deep brain stimulation. Several technical issues and stimulation paradigms have been and are still being developed to optimize the therapeutic effects, minimize the side effects and facilitate handling. This review summarizes current therapeutic issues, i.e., patient and target selection, surgical procedure and programming paradigms. In addition it focuses on neuropsychological effects and side effects of deep brain stimulation.

Pacific Northwest National Laboratory’s Climate Resiliency Planning Process and Lessons Learned

Energy Technology Data Exchange (ETDEWEB)

Fowler, Kimberly M. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Judd, Kathleen S. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Brandenberger, Jill M. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

2016-02-22

In 2015, the Pacific Northwest National Laboratory (PNNL) developed its first Climate Resilience Plan for its Richland Campus. PNNL has performed Climate Resilience Planning for the Department of Defense, Nuclear Regulatory Commission, and Department of Energy (DOE) over the past 5 years. The assessment team included climate scientists, social scientists, engineers, and operations managers. A multi-disciplinary team was needed to understand the potential exposures to future changes at the site, the state of the science on future impacts, and the best process for “mainstreaming” new actions into existing activities. The team uncovered that the site’s greatest vulnerabilities, and therefore priorities for climate resilience planning, are high temperature due to degraded infrastructure, increased wildfire frequency, and intense precipitation impacts on stormwater conveyance systems.

Children’s Exposure to Environmental Contaminants: An Editorial Reflection of Articles in the IJERPH Special Issue Entitled, “Children’s Exposure to Environmental Contaminants”

Directory of Open Access Journals (Sweden)

Alesia Ferguson

2016-11-01

Full Text Available Children are at increased vulnerability to many environmental contaminants compared to adults due to their unique behavior patterns, increased contaminant intake per body weight, and developing biological systems. Depending upon their age, young children may crawl on the floor and may practice increased hand to mouth activity that may increase their dose-intake of specific contaminants that accumulate in dust and other matrices. Children are also smaller in size than adults, resulting in a greater body burden for a given contaminant dose. Because children undergo rapid transitions through particular developmental stages they are also especially vulnerable during certain growth-related time windows. A Special Issue was organized focused on the latest findings in the field of children’s environmental exposure for these reasons. This editorial introduces articles in this Special Issue and emphasizes their main findings in advancing the field. From the many articles submitted to this Special Issue from around the world, 23 were accepted and published. They focus on a variety of research areas such as children’s activity patterns, improved risk assessment methods to estimate exposures, and exposures in various contexts and to various contaminants. The future health of a nation relies on protecting the children from adverse exposures and understanding the etiology of childhood diseases. The field of children’s environmental exposures must consider improved and comprehensive research methods aimed at introducing mitigation strategies locally, nationally, and globally. We are happy to introduce a Special Issue focused on children’s environmental exposure and children’s health and hope that it contributes towards improved health of children.

The DOE transportation strategy: Public information, communications network and issue resolution

International Nuclear Information System (INIS)

Philpott, R.E.

1986-01-01

The OCRWM plans to issue a draft ''comprehensive transportation plan'' in the fall of 1987 that combines the Institutional Plan, the Transportation Business Plan (DOE/RW-0046, January 1986), and a framework for transportation operational procedures. This paper reviews the major elements of the OCRWM's institutional strategy. The OCRWM's strategy for addressing transportation issues relies on the development of public information to foster public understanding and acceptance of program activities and goals, and active communication and interaction with all parties having an interest in the development and operation of the NWPA transportation program. The OCRWM's goal in conducting such activities is to foster cooperative effort in addressing transportation issues, and to focus on communication and constructive interaction rather than conflict

76 FR 53853 - Approval and Promulgation of Implementation Plans and Designation of Areas for Air Quality...

Science.gov (United States)

2011-08-30

... Action Network (LEAN) v. EPA, No. 02-60991). The issues raised concerned EPA's decision to approve... Ambient Air Quality Standard,'' Memorandum from John S. Seitz, Director, Office of Air Quality Planning...

NO NEUTRON STAR COMPANION TO THE LOWEST MASS SDSS WHITE DWARF

International Nuclear Information System (INIS)

Agueeros, Marcel A.; Camilo, Fernando; Heinke, Craig; Kilic, Mukremin; Anderson, Scott F.; Silvestri, Nicole M.; Freire, Paulo; Kleinman, Scot J.; Liebert, James W.

2009-01-01

SDSS J091709.55+463821.8 (hereafter J0917+4638) is the lowest surface gravity white dwarf (WD) currently known, with log g = 5.55 ± 0.05 (M ∼ 0.17 M sun ). Such low-mass white dwarfs (LMWDs) are believed to originate in binaries that evolve into WD/WD or WD/neutron star (NS) systems. An optical search for J0917+4638's companion showed that it must be a compact object with a mass ≥0.28 M sun . Here we report on Green Bank Telescope 820 MHz and XMM-Newton X-ray observations of J0917+4638 intended to uncover a potential NS companion to the LMWD. No convincing pulsar signal is detected in our radio data. Our X-ray observation also failed to detect X-ray emission from J0917+4638's companion, while we would have detected any of the millisecond radio pulsars in 47 Tuc. We conclude that the companion is almost certainly another WD.

Technical planning activity: Final report