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Sample records for plan pln-2498

  1. 40 CFR 52.2498 - Visibility protection.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Visibility protection. 52.2498 Section 52.2498 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Washington § 52.2498 Visibility protection...

  2. Next Generation Nuclear Plant Methods Technical Program Plan -- PLN-2498

    Energy Technology Data Exchange (ETDEWEB)

    Richard R. Schultz; Abderrafi M. Ougouag; David W. Nigg; Hans D. Gougar; Richard W. Johnson; William K. Terry; Chang H. Oh; Donald W. McEligot; Gary W. Johnsen; Glenn E. McCreery; Woo Y. Yoon; James W. Sterbentz; J. Steve Herring; Temitope A. Taiwo; Thomas Y. C. Wei; William D. Pointer; Won S. Yang; Michael T. Farmer; Hussein S. Khalil; Madeline A. Feltus

    2010-09-01

    One of the great challenges of designing and licensing the Very High Temperature Reactor (VHTR) is to confirm that the intended VHTR analysis tools can be used confidently to make decisions and to assure all that the reactor systems are safe and meet the performance objectives of the Generation IV Program. The research and development (R&D) projects defined in the Next Generation Nuclear Plant (NGNP) Design Methods Development and Validation Program will ensure that the tools used to perform the required calculations and analyses can be trusted. The Methods R&D tasks are designed to ensure that the calculational envelope of the tools used to analyze the VHTR reactor systems encompasses, or is larger than, the operational and transient envelope of the VHTR itself. The Methods R&D focuses on the development of tools to assess the neutronic and thermal fluid behavior of the plant. The fuel behavior and fission product transport models are discussed in the Advanced Gas Reactor (AGR) program plan. Various stress analysis and mechanical design tools will also need to be developed and validated and will ultimately also be included in the Methods R&D Program Plan. The calculational envelope of the neutronics and thermal-fluids software tools intended to be used on the NGNP is defined by the scenarios and phenomena that these tools can calculate with confidence. The software tools can only be used confidently when the results they produce have been shown to be in reasonable agreement with first-principle results, thought-problems, and data that describe the “highly ranked” phenomena inherent in all operational conditions and important accident scenarios for the VHTR.

  3. 46 CFR 249.8 - Limitation on risk.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Limitation on risk. 249.8 Section 249.8 Shipping... OPERATORS APPROVAL OF UNDERWRITERS FOR MARINE HULL INSURANCE § 249.8 Limitation on risk. (a) Underwriters may take a line on any single risk in excess of five percent of its Policyholders' Surplus only with...

  4. PLN's experience with the WASP-III model in generation expansion planning for the Java system

    International Nuclear Information System (INIS)

    Sudja, N.; Afiff, A.; Simarmata, B.

    1988-01-01

    The State Electric Power Corporation of Indonesia (PLN) was one of the first recipients of the WASP computer model, and since 1976 has been using the model (first the version WASP-II, and later the WASP-III version) for carrying out generation expansion planning studies for the country, and particularly, for the Java power system. This paper discusses PLN's experience with WASP-III and comments on some problems and constraints encountered, particularly: the time-fixed forced outage rate (FOR) assumed for generating units, simulation of the hydro system and computation time. The paper concludes with some suggestions about future enhancements to WASP-III. (author). 3 figs, 11 tabs

  5. Next Generation Nuclear Plant Methods Research and Development Technical Program Plan -- PLN-2498

    Energy Technology Data Exchange (ETDEWEB)

    Richard R. Schultz; Abderrafi M. Ougouag; David W. Nigg; Hans D. Gougar; Richard W. Johnson; William K. Terry; Chang H. Oh; Donald W. McEligot; Gary W. Johnsen; Glenn E. McCreery; Woo Y. Yoon; James W. Sterbentz; J. Steve Herring; Temitope A. Taiwo; Thomas Y. C. Wei; William D. Pointer; Won S. Yang; Michael T. Farmer; Hussein S. Khalil; Madeline A. Feltus

    2008-09-01

    One of the great challenges of designing and licensing the Very High Temperature Reactor (VHTR) is to confirm that the intended VHTR analysis tools can be used confidently to make decisions and to assure all that the reactor systems are safe and meet the performance objectives of the Generation IV Program. The research and development (R&D) projects defined in the Next Generation Nuclear Plant (NGNP) Design Methods Development and Validation Program will ensure that the tools used to perform the required calculations and analyses can be trusted. The Methods R&D tasks are designed to ensure that the calculational envelope of the tools used to analyze the VHTR reactor systems encompasses, or is larger than, the operational and transient envelope of the VHTR itself. The Methods R&D focuses on the development of tools to assess the neutronic and thermal fluid behavior of the plant. The fuel behavior and fission product transport models are discussed in the Advanced Gas Reactor (AGR) program plan. Various stress analysis and mechanical design tools will also need to be developed and validated and will ultimately also be included in the Methods R&D Program Plan. The calculational envelope of the neutronics and thermal-fluids software tools intended to be used on the NGNP is defined by the scenarios and phenomena that these tools can calculate with confidence. The software tools can only be used confidently when the results they produce have been shown to be in reasonable agreement with first-principle results, thought-problems, and data that describe the “highly ranked” phenomena inherent in all operational conditions and important accident scenarios for the VHTR.

  6. 7 CFR 249.8 - Level of benefits and eligible foods.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Level of benefits and eligible foods. 249.8 Section...) Participant Benefits § 249.8 Level of benefits and eligible foods. (a) General. State agencies must identify..., such as prunes (dried plums), raisins (dried grapes), sun-dried tomatoes, or dried chili peppers are...

  7. STRATEGI KOMUNIKASI DIVISI PUBLIC RELATIONS PLN DISTRIBUSI JAWA BARAT DALAM SOSIALISASI SUBSIDI LISTRIK TEPAT SASARAN

    Directory of Open Access Journals (Sweden)

    Lyza Audina Pangesti

    2018-03-01

    Full Text Available ABSTRACTThis thesis discuss about the communication  strategy which have been implemented by public relationsof PLN due to socializing well-targeted electricity subsidy program in West Java. This Well-targetedelectricity subsidy program is a government program which cuts the electricity subsidy for middleincome homes 900—watt customer, where West Java province is ranked the highest in Indonesia. Thegoal of this research is to know the steps of communication strategy which have been implementedby public relations PLN West Java Distribution due to socializing well-targeted electricity subsidy program. This research uses constructivist paradigm, qualitative approach and case-study research strategy. The data were collected by in depth interview and documentation study. The result revealed thatthe public relations of PLN becomes one of the communicator who planned and give the instructions topublic relations of PLN West Java Distribution in socializing well-targeted electricity subsidy program.The communication strategy steps which have been implemented by public relations of PLN due tosocializing well-targeted electricity subsidy program are determined the communicator, recognizes theaudiences, set the method and last selection and media uses. Key words: Communication Strategy, Public Relations, PT PLN

  8. Penerapan Budaya Organisasi pada Pt.pln(persero) Rayon Bangkinang

    OpenAIRE

    ", Kasmiruddin; Supariyanto, Sugeng

    2014-01-01

    This research was conducted at PT. PLN (Persero) rayon Bangkinang with the title on the application oforganizational culture PT.PLN (Persero) Rayon Bangkinang. Knowing the purpose of this study is theapplication of organizational culture on PT. PLN (Persero) Rayon Bangkinang. And the benefits of thisresearch is to add insight and understanding of science in the field of Human Resource Management and toto increase knowledge and understanding of the culture of the organization but also for the ...

  9. Role of plnB gene in the regulation of bacteriocin production in Lactobacillus paraplantarum L-XM1.

    Science.gov (United States)

    Zhang, Xiangmei; Shang, Nan; Zhang, Xu; Gui, Meng; Li, Pinglan

    2013-06-12

    Homologues of plnB gene have been shown to participate in regulation of bacteriocin production through quorum sensing system in other organisms, to investigate the possible role of plnB gene in Lactobacillus paraplantarum L-XM1, we cloned and insertionally inactivated the plnB gene. The plnB knockout mutant ΔplnB21 showed loss of bacteriocin production, its Bac⁺ phenotype could not be restored even after the addition of PlnA. Furthermore, reverse transcription-PCR analysis from total RNA preparations showed that the bacteriocin structural genes of the plnEF and plnJK were not transcribed in the plnB knockout mutant compared with the wild-type strain. It was therefore concluded that plnB is invovled in a quorum sensing based bacteriocin production. This is the first demonstration of a role for plnB by gene knockout in L. paraplantarum. Copyright © 2012 Elsevier GmbH. All rights reserved.

  10. YgdE is the 2'-O-ribose methyltransferase RlmM specific for nucleotide C2498 in bacterial 23S rRNA

    DEFF Research Database (Denmark)

    Purta, Elzbieta; O'Connor, Michelle; Bujnicki, Janusz M

    2009-01-01

    The rRNAs of Escherichia coli contain four 2'-O-methylated nucleotides. Similar to other bacterial species and in contrast with Archaea and Eukaryota, the E. coli rRNA modifications are catalysed by specific methyltransferases that find their nucleotide targets without being guided by small...... complementary RNAs. We show here that the ygdE gene encodes the methyltransferase that catalyses 2'-O-methylation at nucleotide C2498 in the peptidyl transferase loop of E. coli 23S rRNA. Analyses of rRNAs using MALDI mass spectrometry showed that inactivation of the ygdE gene leads to loss of methylation...... at nucleotide C2498. The loss of ygdE function causes a slight reduction in bacterial fitness. Methylation at C2498 was restored by complementing the knock-out strain with a recombinant copy of ygdE. The recombinant YgdE methyltransferase modifies C2498 in naked 23S rRNA, but not in assembled 50S subunits...

  11. PENJABARAN GOOD CORPORATE GOVERNANCE (GCG DALAM PENGADAAN BARANG DAN JASA PADA PLN BALI

    Directory of Open Access Journals (Sweden)

    Luh Putu Dwi Suarini

    2015-07-01

    Full Text Available Research in connection with the theme is “ Implementation of Good Corporate Governance (GCG in Procurement at PLN Bali”. The problems are researched the translation of good corporate governace forms in the procurement of goods and services at PLN Bali and the form of the procurement of goods and services at PLN Bali. This research includes the category of empirical legal research, legal research is a empirical means reviewing the practical reality in daily life - today. The nature of the research is descriptive research that has a goal to paint a picture of something in the area and at a certain moment. Furthermore, the technique used is to study documents, interviews, Non-Probability Sampling, purposive sampling. Procurement of goods or services in PLN involves many parties, the employees who were appointed to take care of such procurement and future providers of goods and services. In this relationship unfair business competition or the price is too high or low in supply. However, the existence of e-procurement and the correct procedures in the procurement of goods and services as well as the concept of GCG which also animates the principles of procurement of goods and services. Procedures in the procurement of goods and services as well as the principles of GCG, the procurement in PLN can be carried out transparently, responsibly, independently, fairly and equitably.

  12. DESAIN PEMIPIL JAGUNG DENGAN SUMBER ENERGI TENAGA SURYA DAN ENERGI LISTRIK PLN

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    Hasyim Asy’ari

    2015-09-01

    Hasi lpercobaan pertama dilakukan pada intensitas cahaya 103700 lux tegangan 19 V dan arus 2 A menghasilkan  kecepatan putar 1705 Rpm sehingga mesin pemipil jagung bekerja dengan sangat baik dengan waktu pemipilan 0,10 menit per jagung. Begitu seterusnya dengan intensitas yang berbeda sampai ke intensitas terendah yaitu 29300 lux tegangan 8,2 V dan arus 1 A menghasilkan kecepatan putar 402,4 Rpm sehingga mesin pemipil jagung tidak mampu lagi bekerja dengan baik (tidak dapat memipil jagung lagi. percobaan selanjutnya untuk melakukan pemipilan dengan energi listrik PLN disaat mesin pemipil jagung tidak mendapatkan suplai energi yang cukup dari panel surya karena intensitas cahaya yang rendah maka mesin dapat berpindah kesumber energi lain dengan memindahkan sumber energi ke listrik PLN. Pada penelitian ini didapati hasil setelah listrik PLN dikonversikan dengan konverter menunjukkan tegangan 11,2 V, arus 1,5 A dan kecepatan putar 910,2 Rpm sehingga didapati waktu pemipilan adalah 0,19 menit per jagung.

  13. Media Sosial dan Peran Manajerial Public Relations PT PLN Persero

    Directory of Open Access Journals (Sweden)

    Narayana Mahendra Prastya

    2013-12-01

    Full Text Available Abstract: Social media affect communication technicians and managerial roles in Public Relations (PR. This study observes PR managerial role in PT PLN Persero in the policy making of social media use for the company’s internal environment. This research use interviews, document studies, and observation as data collection techniques. The results show that the role of communicating the policy is more dominant than the managerial role. Factors influencing PR managerial role are organization’s recognition on the PR role and function in the organization, the number of personnel in the PR department, and the authority overlap within the organization.   Abstrak: Media sosial memengaruhi praktek Public Relations (PR sebagai teknisi komunikasi dan manajerial. Penelitian ini membahas peran manajerial PR d PT PLN Persero dalam penyusunan kebijakan penggunaan media sosial untuk lingkungan internal perusahaan. Penelitian menggunakan metode kualitatif dengan teknik pengumpulan data wawancara, studi dokumen, dan observasi. Hasil penelitian menunjukkan bahwa Bidang Komunikasi Korporat PT PLN Persero sudah melaksanakan peran manajerial walaupun masih didominasi peran mengomunikasikan kebijakan. Peran manajerial PR dipengaruhi oleh pemahaman dan pengakuan formal organisasi terhadap peran dan fungsi PR dalam organisasi, jumlah personel di departemen PR, dan tumpang tindih kewenangan dengan bidang kerja lain dalam organisasi.

  14. Penyusunan Perencanaan Keberlangsungan Bisnis PT PLN (Persero APD Jateng dan DIY dengan ISO 22301 dan Metode OCTAVE

    Directory of Open Access Journals (Sweden)

    Azmi Afifah Zahra

    2017-01-01

    Full Text Available Abstrak— Penelitian dalam tugas akhir ini adalah melakukan penyusunan perencanaan keberlangsungan bisnis teknologi informasi pada PT PLN (Persero APD Jateng dan DIY dengan berbasis risiko sebagai bentuk kesiapan perusahaan dalam menangani risiko dan dampak bisnis yang mengancam perusahaan. PT PLN (Persero APD Jateng dan DIY menggunakan sistem dan layanan TI sebagai daya dukung perusahaan dalam mencapai tujuannya. Penggunaan sistem dan layanan TI tersebut tidak terlepas dari adanya ancaman pada risiko sistem dan layanan TI serta dampak dari proses bisnis yang dijalankan oleh tiap fungsi bisnis perusahaan. Dalam proses penyusunan untuk perencanaan keberlangsungan bisnis akan dibuat terlebih dahulu alur kerja untuk kegiatan pengelolaan keberlangsungan bisnis (Business Continuity Management untuk PT PLN (Persero APD Jateng dan DIY dengan menggunakan acuan ISO 22301: 2012 dan alur kerja yang telah diterapkan oleh perusahaan lain yaitu dari Perusahaan Chubu Electric Power Company Group dan DHS Electricity dengan tetap memberikan prosedur praktis yang dapat disesuaikan oleh PT PLN (Persero APD Jateng dan DIY. Hasil akhir dari penelitian ini adalah berupa rekomendasi penerapan alur kerja dan strategi keberlangsungan bisnis untuk PT PLN (Persero berdasarkan pada risiko aset TI yang menjadi tanggung jawab tim SCADA dan Telekomunikasi.

  15. Tinjauan Hukum Terhadap Perjanjian Jual Beli Tenaga Listrik Antara PT. Pln (Persero) Dengan Pelanggan

    OpenAIRE

    SIMANJUNTAK, DEWI LESTARI

    2013-01-01

    The increasing growth of population, followed by the development of equipment and infrastructure and the increasing economic and business development need the availability and the increase in electricity in order to provide adequate, equally distributed, and good servicing electricity. The availability of electricity owned by the government and run by PT PLN is based on the legal provisions which state that PT PLN is the authorized representative in electric power system so tha...

  16. ANALISIS PENERIMAAN PEMBAYARAN LISTRIK PASKA BAYAR DAN PRABAYAR TERHADAP PENDAPATAN PT. PLN di NGAWI

    Directory of Open Access Journals (Sweden)

    Nurul Janahti

    2013-01-01

    Full Text Available The purpose of this study was to determine how the effectiveness of the receipt of payment postpaid and prepaid electricity to earnings PT. PLN in Ngawi. Type of research by the author is a qualitative descriptive study, the type of data the author was interviewing, observation and data analysis methods are collected, compiled, interpreted, analyzed, thus providing a complete description. Based on the research conducted, the authors conclude that the effectiveness tinggkat between postpaid and prepaid electricity in 2011 was still effective prepaid electricity, but for greater earnings power postpaid. For postpaid electricity ineffective due each month PT. PLN UPJ Ngawi suffered losses from delinquent customers and for prepaid electricity more effectively but the amount of prepaid electricity customers still small. Contributions related electric revenue postpaid and prepaid electricity PT.PLN UPJ Ngawi more profitable prepaid electricity, because of the effectiveness of the payment easier to use a prepaid system, it is also proportional to the increased number of prepaid subscribers in 2011.

  17. Peran Motivasi Kerja dalam Memoderasi Pengaruh Kepuasan Kerja Karyawan dan Komitmen Organisasi terhadap Kinerja Karyawan PT. PLN (Persero

    Directory of Open Access Journals (Sweden)

    Hartiwi Prabowo

    2013-05-01

    Full Text Available Employee performance is a major factor determining organizational success. Various complaints that arise related to power outages and high electricity tariff increase people demand as consumers on excellent service. Total consumers of PLN Disjaya reach 3,759,546 subscribers (March 2011, it is one unit that has the largest number of subscribers compared to other PLN units, and also provides the largest contribution to revenue. On a survey of Integrity, PLN Disjaya service from 2006 to 2010 showed that over the last five years, PLN Disjaya integrity is below target. The purpose of this study is to analyze the role of motivation in moderating influence between job satisfaction and organizational commitment partially and simultaneously on employee performance. Data collection techniques used questionnaires to 160 employees as respondents; data analysis techniques used Regresion Moderated Analysis (MRA. The results showed the role of motivation can moderate the job satisfaction on employee performance, but by individual motivation cannot moderate the commitment to employee performance.

  18. PERBEDAAN KEPUASAN KERJA PADA PEGAWAI OUTSOURCING DENGAN PEGAWAI TETAP PT. PLN (PERSERO

    Directory of Open Access Journals (Sweden)

    Annisa N. Amrullah

    2018-02-01

    Full Text Available Industrial employee recently faced outsourcing system, a process transfering bisnis activity to the third parties. This system will give an impact to job satisfaction of the employee if they feel unfairly treated such as no fringe benefit and discriminated salary. This comparative research design compared between 45 permanent employee and 75 outsourcing employee at PT. PLN (PERSERO UPJ Baleendah. Instrument used is job satisfaction scales from Herzberg. Statistical analysis used U Mann Whitney to test hypothesis proposed. Result using 95% trusted degree (α = 0,05 found p > α. It is concluded that Ho is accepted and H1 is not. Therefore, there is no significant differences between  outsourcing employee and permanent employee at di PT. PLN (PERSERO.

  19. Genetic Variation of pln Loci Among Probiotic Lactobacillus plantarum Group Strains with Antioxidant and Cholesterol-Lowering Ability.

    Science.gov (United States)

    Devi, Sundru Manjulata; Halami, Prakash M

    2017-10-13

    In the present study, 14 different plantaricin-encoding genes of pln loci were studied and compared to available sequences from public domain database of probiotic Lactobacillus plantarum strains. Based upon the presence and absence of selected genes, pln locus was grouped into eight clusters. Further, quantitative real-time PCR (qRT-PCR) analysis for seven genes has discriminated the complex pln locus into five types which includes WCFS1 (in Lactobacillus plantarum subsp. plantarum MCC 2976 and MCC 2974 and Lactobacillus paraplantarum MCC 2978), closely related to J51 (in Lb. paraplantarum MCC 2973 and MCC 2977), J23 (in Lb. plantarum MTCC 5422), NC8 (in Lb. paraplantarum MTCC 9483), and a new E1 type (in Lb. plantarum subsp. plantarum E1). It was observed that the plnA, EF, NC8βα, NC81F, NC8HK, and G were expressed in E1 strain. Further, southern hybridization confirmed the chromosome-encoded plantaricin in Lb. plantarum group (LPG) strains. Several PCR assays and DNA sequence analysis of the regions amplified in pln loci of E1 isolate suggested a hybrid variant of NC8 and J51 plantaritypes. This indicates the wide distribution of plantaricin with remarkable variation, diversity, and plasticity among the LPG strains of vegetable origin. Further, the selected strains were able to reduce the growth of Kocuria rhizophila ATCC 9341 by 40-54% within 6 h of co-incubation under in vitro pathogen exclusion assay. These isolates also possessed cholesterol-lowering and antioxidant activity suggesting their application in the development of functional foods.

  20. Modeling the Frequency of Cyclists’ Red-Light Running Behavior Using Bayesian PG Model and PLN Model

    Directory of Open Access Journals (Sweden)

    Yao Wu

    2016-01-01

    Full Text Available Red-light running behaviors of bicycles at signalized intersection lead to a large number of traffic conflicts and high collision potentials. The primary objective of this study is to model the cyclists’ red-light running frequency within the framework of Bayesian statistics. Data was collected at twenty-five approaches at seventeen signalized intersections. The Poisson-gamma (PG and Poisson-lognormal (PLN model were developed and compared. The models were validated using Bayesian p values based on posterior predictive checking indicators. It was found that the two models have a good fit of the observed cyclists’ red-light running frequency. Furthermore, the PLN model outperformed the PG model. The model estimated results showed that the amount of cyclists’ red-light running is significantly influenced by bicycle flow, conflict traffic flow, pedestrian signal type, vehicle speed, and e-bike rate. The validation result demonstrated the reliability of the PLN model. The research results can help transportation professionals to predict the expected amount of the cyclists’ red-light running and develop effective guidelines or policies to reduce red-light running frequency of bicycles at signalized intersections.

  1. ANALISIS SISTEM ANTRIAN PADA LOKET PEMBAYARAN PT. PLN (PERSERO AREA BALI SELATAN RAYON KUTA

    Directory of Open Access Journals (Sweden)

    NGURAH GDE PRABA MARTHA

    2012-09-01

    Full Text Available The purpose of the analysis of queuing systems is to find out the model and the performance of queuing system was run. The research was conducted at PT. PLN (Persero South Bali Area Rayon Kuta and the issue raised is about the analysis of queuing systems at the payment counter. Model queue is determined based on the Kendall notation and performance of queuing systems can be determined by calculating the utilization factor. At payment counter, the queuing model used is a model (M/G/4:(GD/?/?. The performance of queuing system at payment counter of PT. PLN (Persero South Bali Area Rayon Kuta is less effective because each servers was busy on average only between 30% – 50% of working hours so that more time unemployed servers.

  2. Technical Analysis Feasibility Study on Smart Microgrid System in Sekolah Tinggi Teknik PLN

    Science.gov (United States)

    Suyanto, Heri

    2018-02-01

    Nowadays application of new and renewable energy as main resource of power plant has greatly increased. High penetration of renewable energy into the grid will influence the quality and reliability of the electricity system, due to the intermittent characteristic of new and renewable energy resources. Smart grid or microgrid technology has the ability to deal with this intermittent characteristic especially if these renewable energy resources integrated to grid in large scale, so it can improve the reliability and efficiency of the grid. We plan to implement smart microgrid system at Sekolah Tinggi Teknik PLN as a pilot project. Before the pilot project start, the feasibility study must be conducted. In this feasibility study, the renewable energy resources and load characteristic at the site will be measured. Then the technical aspect of this feasibility study will be analyzed. This paper explains that analysis of ths feasibility study.

  3. Strategi Public Relations dalam Mendukung Pemasaran Pembangkit Listrik Nasional (PLN

    Directory of Open Access Journals (Sweden)

    Novi Anggraeni

    2014-07-01

    Full Text Available Public relations is one of the elements that determine the viability of an organization positively. The purpose of the research; 1. Knowing the planning public relations strategies in support of marketing; 2. Knowing the kinds of public relations activities; 3. Knowing the packaging contents of the message of the communication media used; 4. Knowing the effect to be achieved; and 5. Knowing the obstacles faced. The method used descriptive qualitative. Results of the study are: 1. Judging from the background criteria for Public Relations of PT. PLN (Persero APJ Cirebon is formal education, job experience, appearance, skills, individual characteristics, and adaptation, credible communicator. 2. Kegiatan Public Relations to support the marketing of which the existence of a local radio talk show in Cirebon (Cirebon FM, a local television talk show in Cirebon (RCTV, cooperation in carrying out tasks related to corporate law. 3. Packaging persuasive message content, preparation of informative messages are intended to provide excitement and build consumer understanding. 4. The effect achieved a change in opinions, attitudes and behavior. 5. Barriers found limited use of communication media and the lack of communication superiors and subordinates

  4. Aplikasi Data Pelanggan Berbasis Java dan Mobile pada PT. PLN (Persero Area Semarang

    Directory of Open Access Journals (Sweden)

    Rizaldi Habibie

    2016-01-01

    Full Text Available In modern times, like today, the role of software or applications that run on top of the platform is very important. This is because almost all of the work done by the people, made by the software or application. Applications can be used to assist in the processing of data and upload the final report. Data recorded previously processed by the paper can be recorded and processed by the application so that more efficiently. PT. PLN (Persero Semarang District State electricity company has many customers in the city of Semarang. Customer data belonging to this company has not been processed in digital form. This causes the data of regular visits undertaken are not directly connected with customer data, owned so inefficient and requires a long process in the course of the report. Thus, it takes an application that can help in the treatment of customer data, data of visited consumer, and generate reports . Customer data Java-based and mobile applications for PLN (Persero Semarang District State intended for the treatment of customer data, data of visited connsumer and generate reports. The application consists of two application. The first applications developed using the programming language Java, which can run on the operating system Windows. The second application was designed and implemented using the framework ionic, which can run on the Android operating system. This application uses MySQL as a database management system, which is used for data storage media.

  5. STRATEGI KOMUNIKASI DIVISI PUBLIC RELATIONS PLN DISTRIBUSI JAWA BARAT DALAM SOSIALISASI SUBSIDI LISTRIK TEPAT SASARAN

    OpenAIRE

    Lyza Audina Pangesti

    2018-01-01

    ABSTRACTThis thesis discuss about the communication  strategy which have been implemented by public relationsof PLN due to socializing well-targeted electricity subsidy program in West Java. This Well-targetedelectricity subsidy program is a government program which cuts the electricity subsidy for middleincome homes 900—watt customer, where West Java province is ranked the highest in Indonesia. Thegoal of this research is to know the steps of communication strategy which have been implemente...

  6. Persepsi Masyarakat Terhadap Program Corporate Social Responsibility (CSR) PT Pln Sektor Pembangkitan Tarahan Provinsi Lampung

    OpenAIRE

    Nurmayasari, Indah; Gitosaputro, Sumaryo; Kusnani, Dedeh Kurniasih

    2013-01-01

    Indicators of Corporate Social Responsibility programs by PT PLN Tarahan Power Sector, South Lampung are suitability, sustainability, and sociality of CSR programs. CSR programs are given for community and the environment. People who receive the programs will have perceptions. The external and internal factors of individuals suspected related to the perceptions are people€™s age, gender, educational level, emotional level, income level, the number of family members, and benefits of CSR progra...

  7. PENGARUH JUMLAH PELANGGAN PLN, HOTEL, INDUSTRI TERHADAP PENERIMAAN PAJAK PENERANGAN JALAN KOTA

    Directory of Open Access Journals (Sweden)

    Timung Tri Prasetyo

    2017-06-01

    Full Text Available Pajak penerangan jalan berkontribusi besar bagi Kota Semarang. Setiap tahunnya penerimaan pajak penerangan jalan di Kota Semarang selalu melebihi target yang telah ditetapkan. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh jumlah pelanggan PLN, jumlah hotel, jumlah industri terhadap penerimaan pajak penerangan jalan. Objek penelitian ini adalah penerimaan pajak penerangan jalan di Kota Semarang periode  1985-2014. Penelitian ini menggunakan desain penelitian dengan pendekatan kuantitatif. Analisis data menggunakan analisis Regresi Linier Berganda dengan metode Ordinary Least Square (OLS. Berdasarkan hasil penelitian dapat disimpulkan bahwa jumlah pelanggan berpengaruh signifikan terhadap penerimaan pajak penerangan jalan, jumlah hotel berpengaruh signifikan terhadap penerimaan pajak penerangan jalan, jumlah industri berpengaruh signifikan terhadap penerimaan pajak penerangan jalan. Street lighting contribute greatly to the tax for the city of Semarang. Each year a tax receipt street lighting in the city of Semarang have always exceeded the targets that have been set. The purpose of this research is to know the influence of the number of customers PLN, the number of hotels, the amount of the tax receipt against industry street lighting. The object of this study is the tax revenue street lighting in the city of Semarang in the period 1985-2014. This research uses a quantitative approach to design research. Data analysis using Multiple Linear regression analysis with the method of Ordinary Least Square (OLS. Based on the results of the study it can be concluded that the number of influential customers significantly to tax revenues, the number of hotel street lighting effect significantly to tax revenues, the number of street lighting industry's influential tax revenues significantly to street lighting.

  8. Pengaruh Sistem Pembayaran Listrik Online (Payment Point Online Bank Terhadap Pengendalian Internal Kas Pada PT. PLN (Persero DJBB

    Directory of Open Access Journals (Sweden)

    Maulana Yusup

    2012-04-01

    Full Text Available The company has its own way in the benefit and boost profits from year to year. Gains usually obtained sourced from a network perusahaan.System activities related procedures in a comprehensive series to carry out an enterprise activity. Therefore, the service strategy very big influence on the activities of the company. With the waiters are good, it is expected there will be no diversion of the company The research objective was to determine the effect of electricity online payment system (payment points online bank to internal control of cash at PT.PLN (Persero Distribution West Java and Banten Distribution Office. Conventional payment systems that rely on physical cash as a payment instrument has been shifted due to advances in technology can replace conventional ways of containing the risk of endangering safety. Based on research data on the PT. PLN (Persero Distribution West Java and Banten and discussion based on the theory, it can be concluded that the system of online payment of electricity was instrumental in supporting the effectiveness of internal control of cash, it can be seen from (1 The presence of general controls and application controls are adequate. Customers make payment through bank online payment points, (2 Reconciliation of receipt of funds receipt and bookkeeping is done regularly and directed accordingly (2 Process Online Payment System Electrical PPOB (Payment Point Online Bank is an electricity bill payment service and other bills online real -Time. For it can be suggested that understanding is not uniform (the existence of different viewpoints of employees with regard to the value and effect of the application of the company's progress PPOB can be removed and can eliminate the old paradigm of doing business processes PLN and increased knowledge of the mechanism of action of the system so as to improve performance and ultimately increase customer satisfaction and loyalty.

  9. Pengaruh Worklife Balance Dan Kompensasi Terhadap Kinerja Karyawan Pada PT Pln (Persero) Wilayah Suluttenggo Area Manado

    OpenAIRE

    Saina, Ischevell Vialara; Pio, Riane Johnly; Rumawas, Wihelmina

    2016-01-01

    .This study was conducted to determine the effect of Worklife Balance and Compensation for Employee Performance at PT PLN (Persero) Area Manado.Based on the results of the study states that Worklife Balance employees get a fairly good value, employee satisfaction in achieving harmony between the responsibilities in private life, and the responsibilities of work is urgently needed so that employees can work better, Compensation of employees received value very good, with a proper compensation ...

  10. PERANCANGAN SISTEM INFORMASI PENGADUAN PELANGGAN BAGIAN CATER PT PLN CABANG UPJ BEKASI KOTA

    Directory of Open Access Journals (Sweden)

    Eddy Sutedjo

    2007-10-01

    Full Text Available Article discusses the design of user complaint information system on Cater PLN Company Branch UPJ CityBekasi. The design systems consist of complaint acceptance module, scheduled module, field team determinationmodule, and complaint report module. This information system application program testing of user complaint isusing black-box testing method. Black-box testing method was done by giving a number of inputs to the applicationprogram that later processed suitable with the functional needs to produce the needed output. The research resultis the program able to give information about the complaint faster, accurate, and up to date compared to the use ofmanual document.Keywords: information system, customer

  11. APLIKASI REGRESI DATA PANEL DENGAN PENDEKATAN FIXED EFFECT MODEL (STUDI KASUS: PT PLN GIANYAR

    Directory of Open Access Journals (Sweden)

    NI PUTU ANIK MAS RATNASARI

    2014-01-01

    Full Text Available Panel data regression has three approaches. One of these approaches is Fixed Effect Model (FEM. FEM is common estimated using Least Square Dummy Variable. The use of dummy variable in FEM is based on assumption that slope coefficients are constant but intercept varies over individuals. One of application of FEM is to find out motivation of employees at PT PLN Gianyar for non-outsourcing and outsourcing employees based on existence, relatedness, and growth. This research yields the following two models: with 67% motivation non-outsourcing employees represented by existenceand73% motivation non-outsourcing employees represented by existence and growth.

  12. Pengaruh Gaya Kepemimpinan Terhadap Motivasi Kerja Karyawan (Studi Pada Karyawan Pt.pln (Persero) Area Pelayanan Dan Jaringan Malang)

    OpenAIRE

    YustiArini, Lia; Mukzam, M. Djudi; Prasetya, Arik

    2016-01-01

    The purposes of this study are to examine the influence of leadership style including directive leadership style, supportive leadership style, participative leadership style, and achievement oriented leadership style on employees work motivation in PT. PLN (Persero) Malang. The research type is explanatory research with a quantitative approach. The techniques of data analysis are descriptive statistical analysis and multiple linear regression method.The result indicates that the directive le...

  13. Boost first, eliminate systematic error, and individualize CTV to PTV margin when treating lymph nodes in high-risk prostate cancer

    International Nuclear Information System (INIS)

    Rossi, Peter J.; Schreibmann, Eduard; Jani, Ashesh B.; Master, Viraj A.; Johnstone, Peter A.S.

    2009-01-01

    Purpose: The purpose of this report is to evaluate the movement of the planning target volume (PTV) in relation to the pelvic lymph nodes (PLNs) during treatment of high-risk prostate cancer. Patients and methods: We reviewed the daily treatment course of ten consecutively treated patients with high-risk prostate cancer. PLNs were included in the initial PTV for each patient. Daily on-board imaging of gold fiducial markers implanted in the prostate was used; daily couch shifts were made as needed and recorded. We analyzed how the daily couch shifts impacted the dose delivered to the PLN. Results: A PLN clinical target volume was identified in each man using CT-based treatment planning. At treatment planning, median minimum planned dose to the PLN was 95%, maximum 101%, and mean 97%. Daily couch shifting to prostate markers degraded the dose slightly; median minimum dose to the PLN was 92%, maximum, 101%, and mean delivered, 96%. We found two cases, where daily systematic shifts resulted in an underdosing of the PLN by 9% and 29%, respectively. In other cases, daily shifts were random and led to a mean 2.2% degradation of planned to delivered PLN dose. Conclusions: We demonstrated degradation of the delivered dose to PLN PTV, which may occur if daily alignment only to the prostate is considered. To improve PLN PTV, it maybe preferable to deliver the prostate/boost treatment first, and adapt the PTV of the pelvic/nodal treatment to uncertainties documented during prostate/boost treatment

  14. ANALISIS KUALITAS PELAYANAN YANG BERPENGARUH TERHADAP KEPUASAN PELANGGAN MENGGUNAKAN METODE SERVQUAL DAN MODEL KANO (Studi Kasus: PT. PLN UPJ Semarang Selatan

    Directory of Open Access Journals (Sweden)

    Arfan Bakhtiar

    2012-02-01

    Full Text Available Tingginya angka keluhan masyarakat terhadap layanan menuntut PT. PLN (persero untuk mengevaluasi seperti apa tingkat pelayanan yang sudah diberikan kepada masyarakat. Hal tersebut dilakukan untuk membangun citra yang baik di mata masyarakat. Penelitian ini bertujuan untuk mengetahui apakah ada kesenjangan antara layanan yang dipersepsikan oleh pihak manajemen dan harapan pelanggan (gap 1, mengetahui apakah ada kesenjangan antara persepsi dan harapan pelanggan (gap 5 dan menganalisa penyebab terjadinya kesenjangan tersebut, serta menentukan variabel-variabel yang harus diprioritaskan untuk diperbaiki melalui pengintegrasian Metode Servqual dan Model Kano. Hasil penelitian yang dilakukan dengan menggunakan Metode Servqual terhadap lima dimensi kualitas jasa yaitu Tangible, Reliability, Responsiveness, Assurance dan Emphaty untuk gap 1 diketahui bahwa masih terdapat kesenjangan, ditunjukkan dengan nilai servqual yang negatif, untuk gap 5 juga ditemukan masih ada kesenjangan, nilai gap terbesar terdapat pada dimensi Emphaty. Berdasarkan hasil pengintegrasian Metode Servqual dan Model Kano diketahui kriteria yang harus diprioritaskan terlebih dahulu adalah kriteria yang termasuk dalam kategori must-be yang memiliki nilai servqual negatif terbesar, dalam penelitian ini terdapat pada variabel R5 yaitu kondisi KWH meter (perputaran angka sesuai dengan jumlah pemakaian. Kata Kunci: PT. PLN, Kualitas pelayanan, Metode Servqual, Model Kano       High number of public complaints against the service demands has urged PT. PLN (Persero to evaluate what level of service that has been given to community. Therefore, a well service should be build as good representatives in the eyes of society. This study is to determine whether there is a gap between services that are perceived by the management and customer expectations (Gap 1, determine if there is a gap between perception and customer expectations (gap 5 and analyze the causes of these disparities, and to

  15. EVALUASI PENGENDALIAN INTERNAL TERHADAP PENERIMAAN DAN PENGELUARAN KAS PADA PT PLN (PerseroUNIT INDUK PEMBANGUNAN XIII MAKASSAR

    Directory of Open Access Journals (Sweden)

    ESTER DEWI

    2017-05-01

    There is also the purpose of writing is: 1 .To analyze the structure of the organization, 2. Analyze the system mechanisms and procedures for cash receipts and expenditure, 3 Analyze healthy practice associated with research at PT PLN (Persero Parent Unit XIII development Makassar. The purpose of writing, 4. Analyzing the quality and reliability of employees in his work responsibility. The methodology used is the research field research and questionnaires while the analysis used was a descriptive comparative analysis aims to describe the activities of the company, especially in the Internal Control System Cash Receipts and Expenditure.

  16. Idaho National Laboratory Emergency Readiness Assurance Plan — Fiscal Year 2016

    International Nuclear Information System (INIS)

    None, None

    2016-01-01

    Battelle Energy Alliance, LLC, the prime contractor for Idaho National Laboratory (INL), provides this Emergency Readiness Assurance Plan (ERAP) for Fiscal Year 2016 in accordance with DOE O 151.1C, “Comprehensive Emergency Management System.” The ERAP documents the readiness of the INL Emergency Management Program using emergency response planning and preparedness activities as the basis. It describes emergency response planning and preparedness activities, and where applicable, summarizes and/or provides supporting information in tabular form for easy access to data. The ERAP also provides budget, personnel, and planning forecasts for Fiscal Year 2017. Specifically, the ERAP assures the Department of Energy Idaho Operations Office that stated emergency capabilities at INL are sufficient to implement PLN 114, “INL Emergency Plan/RCRA Contingency Plan.”

  17. Idaho National Laboratory Emergency Readiness Assurance Plan — Fiscal Year 2014

    Energy Technology Data Exchange (ETDEWEB)

    Bush, Shane [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2014-09-01

    Battelle Energy Alliance, LLC, the prime contractor for Idaho National Laboratory (INL), provides this Emergency Readiness Assurance Plan (ERAP) for Fiscal Year 2014 in accordance with DOE O 151.1C, “Comprehensive Emergency Management System.” The ERAP documents the readiness of the INL Emergency Management Program using emergency response planning and preparedness activities as the basis. It describes emergency response planning and preparedness activities, and where applicable, summarizes and/or provides supporting information in tabular form for easy access to data. The ERAP also provides budget, personnel, and planning forecasts for Fiscal Year 2015. Specifically, the ERAP assures the Department of Energy Idaho Operations Office that stated emergency capabilities at INL are sufficient to implement PLN-114, “INL Emergency Plan/RCRA Contingency Plan.”

  18. Idaho National Laboratory Emergency Readiness Assurance Plan — Fiscal Year 2016

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2016-09-13

    Battelle Energy Alliance, LLC, the prime contractor for Idaho National Laboratory (INL), provides this Emergency Readiness Assurance Plan (ERAP) for Fiscal Year 2016 in accordance with DOE O 151.1C, “Comprehensive Emergency Management System.” The ERAP documents the readiness of the INL Emergency Management Program using emergency response planning and preparedness activities as the basis. It describes emergency response planning and preparedness activities, and where applicable, summarizes and/or provides supporting information in tabular form for easy access to data. The ERAP also provides budget, personnel, and planning forecasts for Fiscal Year 2017. Specifically, the ERAP assures the Department of Energy Idaho Operations Office that stated emergency capabilities at INL are sufficient to implement PLN 114, “INL Emergency Plan/RCRA Contingency Plan.”

  19. PENGARUH KOMPETENSI PEGAWAI, KEPRIBADIAN PEGAWAI DAN LINGKUNGAN KERJA TERHADAP PELAYANAN DI PERUSAHAAN LISTRIK NEGARA (PLN PEKALONGAN

    Directory of Open Access Journals (Sweden)

    Sari Dian Martha

    2015-06-01

    Full Text Available Saat ini listrik menjadi hal penting dan keberadaannya menjadi pendukung untuk mewujudkan suatu pembangunan. Berdasarkan hasil observasi awal di Perusahaan Listrik Negara (PLN Pekalongan, peneliti menemukan bahwa masih terdapat ketidakpuasan dari pelanggan.adakah pengaruh kompetensi pegawai, kepribadian pegawai dan lingkungan kerja terhadap pelayanan di Perusahaan Listrik Negara (PLN Pekalongan baik secara parsial maupun bersama-sama. Sampel pada penelitian ini berjumlah 115 responden. Metode pengumpulan data menggunakan angket dan dokumentasi. Metode pengolahan dan analisis data menggunakan deskriptif persentase dan regresi linier berganda.Hasil uji regresi linier berganda menunjukkan kompetensi pegawai, kepribadian pegawai dan lingkungan kerja terhadap pelayananmemiliki pengaruh secara simultan dengan taraf signifikansi 0,000< 0,05. Sedangkan secara parsial juga memiliki taraf signifikansi 0,000< 0,05. Hanya variabel lingkungan kerja yang memiliki taraf signifikansi 0,005 < 0,05. Current electricity becomes something important and his whereabouts being stalwart to create a project. Much activity of putting electricity. Based on the results of preliminary observations in the state electricity company in pekalongan, Researchers found that there are still discontent from customers. Is there the influence of competence of employees , the personality of the service employees and work environment in the state electricity company in pekalongan both in the partial and simultaneous. Samples to research are always the 115 respondents.Data collection method poll and using documentation.A method of processing and analysis of data use descriptive the percentage and linear regression worship of idols.Linear regression test double showed competence of employees , the personality of employees and work environment to the economic situation of having simultaneously with the influence of significance 0,000 < 0,05. In partial while also having level of

  20. Alignment Focus of Daily Image Guidance for Concurrent Treatment of Prostate and Pelvic Lymph Nodes

    International Nuclear Information System (INIS)

    Ferjani, Samah; Huang, Guangshun; Shang, Qingyang; Stephans, Kevin L.; Zhong, Yahua; Qi, Peng; Tendulkar, Rahul D.; Xia, Ping

    2013-01-01

    Purpose: To determine the dosimetric impact of daily imaging alignment focus on the prostate soft tissue versus the pelvic bones for the concurrent treatment of the prostate and pelvic lymph nodes (PLN) and to assess whether multileaf collimator (MLC) tracking or adaptive planning (ART) is necessary with the current clinical planning margins of 8 mm/6 mm posterior to the prostate and 5 mm to the PLN. Methods and Materials: A total of 124 kilovoltage cone-beam computed tomography (kV-CBCT) images from 6 patients were studied. For each KV-CBCT, 4 plans were retrospectively created using an isocenter shifting method with 2 different alignment focuses (prostate, PLN), an MLC shifting method, and the ART method. The selected dosimetric endpoints were compared among these plans. Results: For the isoshift contour, isoshift bone, MLC shift, and ART plans, D99 of the prostate was ≥97% of the prescription dose in 97.6%, 73.4%, 98.4%, and 96.8% of 124 fractions, respectively. Accordingly, D99 of the PLN was ≥97% of the prescription dose in 98.4%, 98.4%, 98.4%, and 100% of 124 fractions, respectively. For the rectum, D5 exceeded 105% of the planned D5 (and D5 of ART plans) in 11% (4%), 10% (2%), and 13% (5%) of 124 fractions, respectively. For the bladder, D5 exceeded 105% of the planned D5 (and D5 of ART) plans in 0% (2%), 0% (2%), and 0% (1%) of 124 fractions, respectively. Conclusion: For concurrent treatment of the prostate and PLN, with a planning margin to the prostate of 8 mm/6 mm posterior and a planning margin of 5 mm to the PLN, aligning to the prostate soft tissue can achieve adequate dose coverage to the both target volumes; aligning to the pelvic bone would result in underdosing to the prostate in one-third of fractions. With these planning margins, MLC tracking and ART methods have no dosimetric advantages

  1. Alignment focus of daily image guidance for concurrent treatment of prostate and pelvic lymph nodes.

    Science.gov (United States)

    Ferjani, Samah; Huang, Guangshun; Shang, Qingyang; Stephans, Kevin L; Zhong, Yahua; Qi, Peng; Tendulkar, Rahul D; Xia, Ping

    2013-10-01

    To determine the dosimetric impact of daily imaging alignment focus on the prostate soft tissue versus the pelvic bones for the concurrent treatment of the prostate and pelvic lymph nodes (PLN) and to assess whether multileaf collimator (MLC) tracking or adaptive planning (ART) is necessary with the current clinical planning margins of 8 mm/6 mm posterior to the prostate and 5 mm to the PLN. A total of 124 kilovoltage cone-beam computed tomography (kV-CBCT) images from 6 patients were studied. For each KV-CBCT, 4 plans were retrospectively created using an isocenter shifting method with 2 different alignment focuses (prostate, PLN), an MLC shifting method, and the ART method. The selected dosimetric endpoints were compared among these plans. For the isoshift contour, isoshift bone, MLC shift, and ART plans, D99 of the prostate was ≥97% of the prescription dose in 97.6%, 73.4%, 98.4%, and 96.8% of 124 fractions, respectively. Accordingly, D99 of the PLN was ≥97% of the prescription dose in 98.4%, 98.4%, 98.4%, and 100% of 124 fractions, respectively. For the rectum, D5 exceeded 105% of the planned D5 (and D5 of ART plans) in 11% (4%), 10% (2%), and 13% (5%) of 124 fractions, respectively. For the bladder, D5 exceeded 105% of the planned D5 (and D5 of ART) plans in 0% (2%), 0% (2%), and 0% (1%) of 124 fractions, respectively. For concurrent treatment of the prostate and PLN, with a planning margin to the prostate of 8 mm/6 mm posterior and a planning margin of 5 mm to the PLN, aligning to the prostate soft tissue can achieve adequate dose coverage to the both target volumes; aligning to the pelvic bone would result in underdosing to the prostate in one-third of fractions. With these planning margins, MLC tracking and ART methods have no dosimetric advantages. Copyright © 2013 Elsevier Inc. All rights reserved.

  2. The Effect of Leadership Style, Organizational Culture, Employee Development and Training on Employee Performance (Study of PT. Pln (Persero) Suluttenggo Region)

    OpenAIRE

    Rumokoy, Farlane S.; Lumempow, Irta

    2015-01-01

    An organization or company€™s best asset is human resource or in this case is employee, because employee performance is related to organization or company€™s performance. So, to improve employee performance, company needs people who have expertise and unique capabilities that are in line with company€™s visions and missions. The purpose of this research is to find out the effect of leadership style, organizational culture, employee development and training on employee performance in PT. PLN (...

  3. Desain dan Implementasi Sistem Online Gudang Pada PT. PLN (Persero Distribusi Regional Jawa Tengah dan D.I Yogyakarta

    Directory of Open Access Journals (Sweden)

    Ervin Adhi Cahyanugraha

    2015-01-01

    Full Text Available The information system that can provide complete, accurate information in an integrated way with the ability to reach all people in the system is very important. The criteria are not fulfilled by the warehouse management system on PT. PLN (Persero, distribution of Central Java and Special Region of Yogyakarta. Some districts are not reached by the information system technology; some of them still use Microsoft Office Excel to manage the goods in the warehouse. . So, communication up to rayon is not good, rayon and area are so hard to exchange information, transaction between rayon and area is not quick. this case cause procurement goods is hampered, and this make direct impact to unfinished project . Therefore, the online system of this warehouse can solve the flaw of the old system. The Warehouse Online System is the ASP.Net-based web application. This development process uses Microsoft Visual Studio as the development tools. An information system is not separable from the database as the information data storage; Warehouse Online System uses Oracle as the Relational Database Management System (RDBMS. The Warehouse Online System is suitable with the Standard Operational Procedure (SOP of PT. PLN (Persero. Through Warehouse Online System, the distributors from the area or district can be integrated to communicate, to do the transaction on the material in the warehouse, and to get the access of the user based on their task and authority. Based on the Black Box test, the functions on Warehouse Online System function like what is expected. The maintenance process is still needed to improve the system in the future.

  4. Idaho National Laboratory Integrated Safety Management System FY 2013 Effectiveness Review and Declaration Report

    Energy Technology Data Exchange (ETDEWEB)

    Hunt, Farren [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2013-12-01

    Idaho National Laboratory (INL) performed an Annual Effectiveness Review of the Integrated Safety Management System (ISMS), per 48 Code of Federal Regulations (CFR) 970.5223 1, “Integration of Environment, Safety and Health into Work Planning and Execution.” The annual review assessed Integrated Safety Management (ISM) effectiveness, provided feedback to maintain system integrity, and identified target areas for focused improvements and assessments for Fiscal Year (FY) 2014. Results of the FY 2013 annual effectiveness review demonstrate that the INL’s ISMS program is “Effective” and continually improving and shows signs of being significantly strengthened. Although there have been unacceptable serious events in the past, there has also been significant attention, dedication, and resources focused on improvement, lessons learned and future prevention. BEA’s strategy of focusing on these improvements includes extensive action and improvement plans that include PLN 4030, “INL Sustained Operational Improvement Plan, PLN 4058, “MFC Strategic Excellence Plan,” PLN 4141, “ATR Sustained Excellence Plan,” and PLN 4145, “Radiological Control Road to Excellence,” and the development of LWP 20000, “Conduct of Research.” As a result of these action plans, coupled with other assurance activities and metrics, significant improvement in operational performance, organizational competence, management oversight and a reduction in the number of operational events is being realized. In short, the realization of the fifth core function of ISMS (feedback and continuous improvement) and the associated benefits are apparent.

  5. Estimasi Nilai Pasar Wajar Ekuitas PT Prima Layanan Nasional Enjiniring Dalam Persiapan Initial Public Offering (IPO

    Directory of Open Access Journals (Sweden)

    Ahmad Rizani

    2015-11-01

    Full Text Available PT Prima Layanan Nasional Enjiniring (PT PLN Enjiniring plans to conduct an initial public offering in 2012 that is intended for business development. Purpose of this research was to estimate the fair market value of equity of PT PLN Enjiniring in the framework of an initial public offering. Fair market value of equity of PT PLN Enjiniring is acquired by using discounted cash flow-free cash flow to equity method. Information used for this research come from two secondary data from financial reports and other information contained in the annual report 2008-2010 PT PLN Enjiniring years audited by public accountants, comperative financial reports, and company’s stock data comparison. The estimated fair market value of equity of PT PLN Enjiniring per December 31st 2011 by using the method of discounted cash flow-free cash flow to equity is obtained indication the fair market value of equity amounting to Rp2.583.155.716.515.

  6. Evaluasi Penerapan Internal Control dan Pelaksanaan Good Corporate Governance pada PT PLN (Persero Distribusi Jakarta Raya dan Tangerang

    Directory of Open Access Journals (Sweden)

    Iswandi Iswandi

    2011-11-01

    Full Text Available PT. PLN (Persero Distribusi Jakarta Raya dan Tangerang have implemented Internal Control and Good Corporate Governance. The research would like to evaluate the implementation of Internal Control accordance with COSO’s criteria (Committee of Sponsoring Organizations of the Treadway Commission and KNKG’s criteria (Komite Nasional Kebijakan Governance. Based on research found that five components of COSO such as control environment, risk assessment, control activities, information and communication, monitoring have been implemented but unfortunately one of the component such as control activities not yet implemented properly accordance with COSO’s criteria. The company also have been imlemented GCG accordance with KNKG’s criteria but still need development through internalization GCG’s spirit among the employees because some employees still have different perception related to GCG. For example from employee stand point there’s no problem receive special gift or receive special payment from customer and have a conflict of interest when deal with public accountant.

  7. Integración de un curso MOOC y de un PLN-PLE en un curso presencial sobre fundamentos de la programación

    Directory of Open Access Journals (Sweden)

    Joel Ricardo Jiménez Cruz

    2017-01-01

    Full Text Available En este trabajo se describen las experiencias educativas en un curso sobre Fundamentos d e Programación e n computadoras para alumnos de Ciencias Sociales y Humanidades que integra clases presenciales con elementos de la educación virtual como la participación en un curso masivo y abierto en línea (MOOC y la elaboración de entornos y redes personales de aprend izaje (PLE - PLN. Esta hibridación de componentes presenciales y virtuales requiere de una integración y sincronización adecuada. En este sentido se ha tomado al curso MOOC como un “a yudante” en la impartición de l a parte práctica del curso presencial y en el salón de clases se revisa la parte teórica y se llevan a cabo ejercicios y comentarios que tratan de integrar a las dos modalidades educativas. Esta integración se ve reforzada por el PLN - PLE que cada uno de los estudiantes va desarrollando conforme al avance en clase y en el curso masivo. Los PLNs - PLEs en su conjunto se pueden considerar como ciber - espacios de intercambio de información y construcción del conocimiento. La coordinación central de las actividades de ambas modalidades educativas se realiza por medio de un entorno virtual de enseñanza aprendizaje (EVEA implementado en Moodle. El diseño instruccional que se ha seguido en clases está sustentado por la metodología del aprendizaje basado en proyectos que le permite al profesor y a los alumnos t ener una visión y un objetivo bien planteados desde el principio del ciclo escolar. El marco pedagógico que soporta a los elementos presenciales y virtuales se da dentro de un contexto de aprendizaje conectivista que pretende alcanzar diferentes niveles de interacción e involucramiento cognitivo entre los participantes.

  8. Antagonistic Activity of Lactobacillus plantarum C11: Two New Two-Peptide Bacteriocins, Plantaricins EF and JK, and the Induction Factor Plantaricin A

    Science.gov (United States)

    Anderssen, Erlend L.; Diep, Dzung Bao; Nes, Ingolf F.; Eijsink, Vincent G. H.; Nissen-Meyer, Jon

    1998-01-01

    Six bacteriocinlike peptides (plantaricin A [PlnA], PlnE, PlnF, PlnJ, PlnK, and PlnN) produced by Lactobacillus plantarum C11 were detected by amino acid sequencing and mass spectrometry. Since purification to homogeneity was problematic, all six peptides were obtained by solid-phase peptide synthesis and were tested for bacteriocin activity. It was found that L. plantarum C11 produces two two-peptide bacteriocins (PlnEF and PlnJK); a strain-specific antagonistic activity was detected at nanomolar concentrations when PlnE and PlnF were combined and when PlnJ and PlnK were combined. Complementary peptides were at least 103 times more active when they were combined than when they were present individually, and optimal activity was obtained when the complementary peptides were present in approximately equal amounts. The interaction between complementary peptides was specific, since neither PlnE nor PlnF could complement PlnJ or PlnK, and none of these peptides could complement the peptides constituting the two-peptide bacteriocin lactococcin G. Interestingly, PlnA, which acts as an extracellular signal (pheromone) that triggers bacteriocin production, also possessed a strain-specific antagonistic activity. No bacteriocin activity could be detected for PlnN. PMID:9603847

  9. Analisis Sistem Informasi yang Sedang Berjalan dan Rencana Proyek E-Procurement dengan Pendekatan Metode New Information Economics

    Directory of Open Access Journals (Sweden)

    Idris Gautama So

    2010-05-01

    Full Text Available PT PLN (Persero is a state owned which manages the biggest electricity businesses that cover the entire territory of Indonesia. His position is very potential for the Indonesian public life requires that PLN is able to manage the investment means the supply of electricity to customers. This is done with the information systems that support business processes in the body of PLN. PT PLN (Persero has some application systems, infrastructure, service, and management used to increase the ability of the company. In PLN, there is an application that is capable of supporting PLN to conduct the procurement process is procurement information system (e-procurement. PSI Sub-party service providers as e-procurement to see investment information system (SI and Information Technology (IT which is proportional to the amount issued benefits and bottom-line impact for companies and can find out the level of funds / investment budgets and alignment of Information Technology there is a project in accordance with company requirements. Those needs based on business needs and applications currently running in the intersection so as to project better. Based on this, the author proposes to analyze the benefits of information technology investments by using the method of New Information Economics (NIE that combines the two approaches both financial and non-financial. In the method NIE (New Information Economics will be used four of the five practices that NIE Strategic Demand / Supply Planning, Innovation, Prioritization, and Alignment. The results are expected to help the company to allocate investments SI / IT is more appropriate and supports the company's performance, especially in providing added value to the parties concerned. 

  10. Aphid parasitoids (Hymenoptera, Braconidae, Aphidiinae) from Thailand

    Czech Academy of Sciences Publication Activity Database

    Starý, Petr; Rakhshani, E.; Tomanović, Ž.; Kavallieratos, N. G.; Sharkey, M.

    -, č. 2498 (2010), s. 47-52 ISSN 1175-5326 Grant - others:Ministry of Science of the Republic of Serbia(CS) 143006B; U. S. National Science Foundation(US) DEB 0542864 Institutional research plan: CEZ:AV0Z50070508 Keywords : aphids * parasitoids * biodiversity Subject RIV: EG - Zoology Impact factor: 0.853, year: 2010

  11. Design of nanocarriers for nanoscale drug delivery to enhance cancer treatment using hybrid polymer and lipid building blocks.

    Science.gov (United States)

    Zhang, Rui Xue; Ahmed, Taksim; Li, Lily Yi; Li, Jason; Abbasi, Azhar Z; Wu, Xiao Yu

    2017-01-26

    Polymer-lipid hybrid nanoparticles (PLN) are an emerging nanocarrier platform made from building blocks of polymers and lipids. PLN integrate the advantages of biomimetic lipid-based nanoparticles (i.e. solid lipid nanoparticles and liposomes) and biocompatible polymeric nanoparticles. PLN are constructed from diverse polymers and lipids and their numerous combinations, which imparts PLN with great versatility for delivering drugs of various properties to their nanoscale targets. PLN can be classified into two types based on their hybrid nanoscopic structure and assembly methods: Type-I monolithic matrix and Type-II core-shell systems. This article reviews the history of PLN development, types of PLN, lipid and polymer candidates, fabrication methods, and unique properties of PLN. The applications of PLN in delivery of therapeutic or imaging agents alone or in combination for cancer treatment are summarized and illustrated with examples. Important considerations for the rational design of PLN for advanced nanoscale drug delivery are discussed, including selection of excipients, synthesis processes governing formulation parameters, optimization of nanoparticle properties, improvement of particle surface functionality to overcome macroscopic, microscopic and cellular biological barriers. Future directions and potential clinical translation of PLN are also suggested.

  12. Integrated Waste Treatment Unit GFSI Risk Management Plan

    International Nuclear Information System (INIS)

    W. A. Owca

    2007-01-01

    This GFSI Risk Management Plan (RMP) describes the strategy for assessing and managing project risks for the Integrated Waste Treatment Unit (IWTU) that are specifically within the control and purview of the U.S. Department of Energy (DOE), and identifies the risks that formed the basis for the DOE contingency included in the performance baseline. DOE-held contingency is required to cover cost and schedule impacts of DOE activities. Prior to approval of the performance baseline (Critical Decision-2) project cost contingency was evaluated during a joint meeting of the Contractor Management Team and the Integrated Project Team for both contractor and DOE risks to schedule and cost. At that time, the contractor cost and schedule risk value was $41.3M and the DOE cost and schedule risk contingency value is $39.0M. The contractor cost and schedule risk value of $41.3M was retained in the performance baseline as the contractor's management reserve for risk contingency. The DOE cost and schedule risk value of $39.0M has been retained in the performance baseline as the DOE Contingency. The performance baseline for the project was approved in December 2006 (Garman 2006). The project will continue to manage to the performance baseline and change control thresholds identified in PLN-1963, ''Idaho Cleanup Project Sodium-Bearing Waste Treatment Project Execution Plan'' (PEP)

  13. Structure-function relation of phospholamban: modulation of channel activity as a potential regulator of SERCA activity.

    Directory of Open Access Journals (Sweden)

    Serena Smeazzetto

    Full Text Available Phospholamban (PLN is a small integral membrane protein, which binds and inhibits in a yet unknown fashion the Ca(2+-ATPase (SERCA in the sarcoplasmic reticulum. When reconstituted in planar lipid bilayers PLN exhibits ion channel activity with a low unitary conductance. From the effect of non-electrolyte polymers on this unitary conductance we estimate a narrow pore with a diameter of ca. 2.2 Å for this channel. This value is similar to that reported for the central pore in the structure of the PLN pentamer. Hence the PLN pentamer, which is in equilibrium with the monomer, is the most likely channel forming structure. Reconstituted PLN mutants, which either stabilize (K27A and R9C or destabilize (I47A the PLN pentamer and also phosphorylated PLN still generate the same unitary conductance of the wt/non-phosphorylated PLN. However the open probability of the phosphorylated PLN and of the R9C mutant is significantly lower than that of the respective wt/non-phosphorylated control. In the context of data on PLN/SERCA interaction and on Ca(2+ accumulation in the sarcoplasmic reticulum the present results are consistent with the view that PLN channel activity could participate in the balancing of charge during Ca(2+ uptake. A reduced total conductance of the K(+ transporting PLN by phosphorylation or by the R9C mutation may stimulate Ca(2+ uptake in the same way as an inhibition of K(+ channels in the SR membrane. The R9C-PLN mutation, a putative cause of dilated cardiomyopathy, might hence affect SERCA activity also via its inherent low open probability.

  14. Power plant allocation in East Kalimantan considering total cost and emissions

    Science.gov (United States)

    Muslimin; Utomo, D. S.

    2018-04-01

    The fulfillment of electricity need in East Kalimantan is the responsibility of State Electricity Company/Perusahaan Listrik Negara (PLN). But PLN faces constraints in the lack of generating capacity it has. So the allocation of power loads in East Kalimantan has its own challenges. Additional power supplies from other parties are required. In this study, there are four scenarios tested to meet the electricity needs in East Kalimantan with the goal of minimizing costs and emissions. The first scenario is only by using PLN power plant. The second scenario is by combining PLN + Independent Power Producer (IPP) power plants. The third scenario is by using PLN + Rented power plants. The fourth scenario is by using PLN + Excess capacity generation. Numerical experiment using nonlinear programming is conducted with the help of the solver. The result shows that in the peak load condition, the best combination is scenario 2 (PLN + IPP). While at the lowest load condition, the cheapest scenario is PLN + IPP while the lowest emission is PLN + Rent.

  15. TH-CD-207A-12: Impacts of Inter- and Intra-Fractional Organ Motion for High-Risk Prostate Cancer Stereotactic Body Radiation Therapy

    Energy Technology Data Exchange (ETDEWEB)

    Hassan Rezaeian, N; Chi, Y; Zhou, Y; Tian, Z; Jiang, S; Hannan, R; Jia, X [UT Southwestern Medical Center, Dallas, TX (United States)

    2016-06-15

    Purpose: We are conducting a clinical trial on stereotactic body radiation therapy (SBRT) for high-risk prostate cancer. Doses to three targets, prostate, intra-prostatic lesion, and pelvic lymph node (PLN) region, are escalated to three different levels via simultaneous integrated boost technique. Inter-/intra-fractional organ motions deteriorate planned dose distribution. This study aims at developing a dose reconstruction system to comprehensively understand the impacts of organ motion in our clinical trial. Methods: A 4D dose reconstruction system has been developed for this study. Using a GPU-based Monte-Carlo dose engine and delivery log file, the system is able to reconstruct dose on static or dynamic anatomy. For prostate and intra-prostatic targets, intra-fractional motion is the main concern. Motion trajectory acquired from Calypso in previously treated SBRT patients were used to perform 4D dose reconstructions. For pelvic target, inter-fractional motion is one concern. Eight patients, each with four cone beam CTs, were used to derive fractional motion. The delivered dose was reconstructed on the deformed anatomy. Dosimetric parameters for delivered dose distributions of the three targets were extracted and compared with planned levels. Results: For prostate intra-fractional motion, the mean 3D motion amplitude during beam delivery ranged from 1.5mm to 5.0mm and the average among all patients was 2.61mm. Inter-fractional motion for the PLN target was more significant. The average amplitude among patients was 4mm with the largest amplitude up to 9.6mm. The D95% deviation from planned level for prostate PTVs and GTVs are on average less than<0.1% and this deviation for intra-prostatic lesion PTVs and GTVs were more prominent. The dose at PLN was significantly affected with D{sub 95}% reduced by up to 44%. Conclusion: Intra-/inter-fractional organ motion is a concern for high-risk prostate SBRT, particularly for the PLN target. Our dose reconstruction

  16. Near-field/far-field azimuth and elevation angle estimation using a single vector hydrophone

    Czech Academy of Sciences Publication Activity Database

    Tichavský, Petr; Wong, K. T.; Zoltowski, M.

    2001-01-01

    Roč. 49, č. 11 (2001), s. 2498-2510 ISSN 1053-587X R&D Projects: GA ČR GA102/97/0466; GA ČR GA102/01/0021 Institutional research plan: AV0Z1075907 Keywords : acoustic signal processing * array signal processing * direction-of-arrival estimation Subject RIV: BB - Applied Statistics, Operational Research Impact factor: 1.268, year: 2001

  17. Phospholamban Is Downregulated by pVHL-Mediated Degradation through Oxidative Stress in Failing Heart

    Directory of Open Access Journals (Sweden)

    Shunichi Yokoe

    2017-10-01

    Full Text Available The E3 ubiquitin ligase, von Hippel–Lindau (VHL, regulates protein expression by polyubiquitination. Although the protein VHL (pVHL was reported to be involved in the heart function, the underlying mechanism is unclear. Here, we show that pVHL was upregulated in hearts from two types of genetically dilated cardiomyopathy (DCM mice models. In comparison with the wild-type mouse, both DCM mice models showed a significant reduction in the expression of phospholamban (PLN, a potent inhibitor of sarco(endoplasmic reticulum Ca2+-ATPase, and enhanced interaction between pVHL and PLN. To clarify whether pVHL is involved in PLN degradation in failing hearts, we used carbonylcyanide m-chlorophenylhydrazone (CCCP, a mitochondrial membrane potential (MMP-lowering reagent, to mimic the heart failure condition in PLN-expressing HEK293 cells and found that CCCP treatment resulted in PLN degradation and increased interaction between PLN and pVHL. However, these effects were reversed with the addition of N-acetyl-l-cysteine. Furthermore, the co-transfection of VHL and PLN in HEK293 cells decreased PLN expression under oxidative stress, whereas knockdown of VHL increased PLN expression both under normal and oxidative stress conditions. Together, we propose that oxidative stress upregulates pVHL expression to induce PLN degradation in failing hearts.

  18. Global Threat Reduction Initiative Fuel Thermo-Physical Characterization Project: Sample Management Plan

    Energy Technology Data Exchange (ETDEWEB)

    Casella, Amanda J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Pereira, Mario M. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Steen, Franciska H. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2013-01-01

    This sample management plan provides guidelines for sectioning, preparation, acceptance criteria, analytical path, and end-of-life disposal for the fuel element segments utilized in the Global Threat Reduction Initiative (GTRI), Fuel Thermo-Physical Characterization Project. The Fuel Thermo-Physical Characterization Project is tasked with analysis of irradiated Low Enriched Uranium (LEU) Molybdenum (U-Mo) fuel element samples to support the GTRI conversion program. Sample analysis may include optical microscopy (OM), scanning electron microscopy (SEM) fuel-surface interface analysis, gas pycnometry (density) measurements, laser flash analysis (LFA), differential scanning calorimetry (DSC), thermogravimetry and differential thermal analysis with mass spectroscopy (TG /DTA-MS), Inductively Coupled Plasma Spectrophotometry (ICP), alpha spectroscopy, and Thermal Ionization Mass Spectroscopy (TIMS). The project will utilize existing Radiochemical Processing Laboratory (RPL) operating, technical, and administrative procedures for sample receipt, processing, and analyses. Test instructions (TIs), which are documents used to provide specific details regarding the implementation of an existing RPL approved technical or operational procedure, will also be used to communicate to staff project specific parameters requested by the Principal Investigator (PI). TIs will be developed, reviewed, and issued in accordance with the latest revision of the RPL-PLN-700, RPL Operations Plan. Additionally, the PI must approve all project test instructions and red-line changes to test instructions.

  19. Quorum-Sensing Regulation of Constitutive Plantaricin by Lactobacillus plantarum Strains under a Model System for Vegetables and Fruits

    Science.gov (United States)

    Rizzello, Carlo G.; Filannino, Pasquale; Calasso, Maria; Gobbetti, Marco

    2014-01-01

    This study aimed at investigating the regulatory system of bacteriocin synthesis by Lactobacillus plantarum strains in vegetables and fruits in a model system. Sterile and neutralized cell-free supernatant (CFS) from L. plantarum strains grown in MRS broth showed in vitro antimicrobial activities toward various indicator strains. The highest activity was that of L. plantarum C2. The antimicrobial activity was further assayed on vegetable and fruit agar plates (solid conditions) and in juices (liquid conditions). A regulatory mechanism of bacteriocin synthesis via quorum sensing was hypothesized. The synthesis of antimicrobial compounds seemed to be constitutive under solid conditions of growth on vegetable and fruit agar plates. In contrast, it depended on the size of the inoculum when L. plantarum C2 was grown in carrot juice. Only the inoculum of ca. 9.0 log CFU ml−1 produced detectable activity. The genes plnA, plnEF, plnG, and plnH were found in all L. plantarum strains. The genes plnJK and plnN were detected in only three or four strains. Reverse-phase high-performance liquid chromatography purification and mass spectrometry analysis revealed the presence of a mixture of eight peptides in the most active fraction of the CFS from L. plantarum C2. Active peptides were encrypted into bacteriocin precursors, such as plantaricins PlnJ/K and PlnH and PlnG, which are involved in the ABC transport system. A real-time PCR assay showed an increase in the expression of plnJK and plnG during growth of L. plantarum C2 in carrot juice. PMID:24242246

  20. Inspection Methods in Programming.

    Science.gov (United States)

    1981-06-01

    Counting is a a specialization of Iterative-generation in which the generating function is Oneplus ) Waters’ second category of plan building method...is Oneplus and the initial input is 1. 0 I 180 CHAPTER NINE -ta a acio f igr9-.IeaieGnrtoPln 7 -7 STEADY STATE PLANS 181 TemporalPlan counting...specializalion iterative-generation roles .action(afu nction) ,tail(counting) conslraints .action.op = oneplus A .action.input = 1 The lItcrative-application

  1. Far-infrared soft-mode behavior in PbSc.sub.1/2./sub.Ta.sub.1/2./sub.O.sub.3./sub. thin films

    Czech Academy of Sciences Publication Activity Database

    Kamba, Stanislav; Berta, Milan; Kempa, Martin; Hlinka, Jiří; Petzelt, Jan; Brinkman, K.; Setter, N.

    2005-01-01

    Roč. 98, - (2005), 074103/1-074103/5 ISSN 0021-8979 R&D Projects: GA AV ČR(CZ) IAA1010213; GA ČR(CZ) GA202/04/0993; GA MŠk(CZ) OC 525.20 Institutional research plan: CEZ:AV0Z10100520 Keywords : relaxor ferroelectric * slim films * ferroelectric soft mode * central mode Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 2.498, year: 2005

  2. Power Doppler ultrasound phenotyping of expanding versus collapsed popliteal lymph nodes in murine inflammatory arthritis.

    Directory of Open Access Journals (Sweden)

    Echoe M Bouta

    Full Text Available Rheumatoid arthritis is a chronic inflammatory disease manifested by episodic flares in affected joints that are challenging to predict and treat. Longitudinal contrast enhanced-MRI (CE-MRI of inflammatory arthritis in tumor necrosis factor-transgenic (TNF-Tg mice has demonstrated that popliteal lymph nodes (PLN increase in volume and contrast enhancement during the pre-arthritic "expanding" phase of the disease, and then suddenly "collapse" during knee flare. Given the potential of this biomarker of arthritic flare, we aimed to develop a more cost-effective means of phenotyping PLN using ultrasound (US imaging. Initially we attempted to recapitulate CE-MRI of PLN with subcutaneous footpad injection of US microbubbles (DEFINITY®. While this approach allowed for phenotyping via quantification of lymphatic sinuses in PLN, which showed a dramatic decrease in collapsed PLN versus expanding or wild-type (WT PLN, electron microscopy demonstrated that DEFINITY® injection also resulted in destruction of the lymphatic vessels afferent to the PLN. In contrast, Power Doppler (PD US is innocuous to and efficiently quantifies blood flow within PLN of WT and TNF-Tg mice. PD-US demonstrated that expanding PLN have a significantly higher normalized PD volume (NPDV versus collapsed PLN (0.553 ± 0.007 vs. 0.008 ± 0.003; p0.030 and lower (<0.016 quartile NPDVs in this cohort of mice, which serve as conservative thresholds to phenotype PLN as expanding and collapsed, respectively. Interestingly, of the 12 PLN phenotyped by the two methods, there was disagreement in 4 cases in which they were determined to be expanding by CE-MRI and collapsed by PD-US. Since the adjacent knee had evidence of synovitis in all 4 cases, we concluded that the PD-US phenotyping was correct, and that this approach is currently the safest and most cost-effective in vivo approach to phenotype murine PLN as a biomarker of arthritic flare.

  3. Salmonella in Peripheral Lymph Nodes of Healthy Cattle at Slaughter

    Directory of Open Access Journals (Sweden)

    Hattie E. Webb

    2017-11-01

    Full Text Available To more fully characterize the burden of Salmonella enterica in bovine peripheral lymph nodes (PLN, PLN (n = 5,450 were collected from healthy cattle at slaughter in 12 commercial abattoirs that slaughtered feedlot-fattened (FF cattle exclusively (n = 7, cattle removed (or culled from breeding herds (n = 3, or both FF and cull cattle (n = 2. Qualitative and quantitative methods were used to estimate prevalence and concentration of Salmonella in PLN. Isolates were subjected to a variety of phenotypic, serological, and molecular assays. Overall, Salmonella prevalence in PLN from FF and cull cattle was 7.1 and 1.8%. However, burden varied by season in that observed prevalence in PLN collected in cooler or warmer seasons was 2.4 and 8.2%, respectively. Prevalence in PLN from cull cattle in the southwest region of the US was 2.1 and 1.1% for cool and warm seasons, respectively; however, prevalence in FF PLN was far greater in that it was 6.5 and 31.1%, respectively. Salmonella was recovered from 289 (5.6% PLN and 2.9% (n = 160 of all PLN tested had quantifiable concentrations that varied from 1.6 to 4.9 log10 colony forming units/PLN. The most common serotypes isolated from PLN were Montevideo (26.9%, Lille (14.9%, Cerro (13.0%, Anatum (12.8%, and Dublin (6.9%. In all, 376 unique isolates were collected from the 289 Salmonella-positive PLN. Antimicrobial susceptibility testing revealed the majority (80.6% of these isolates were pansusceptible; however, 10.7% of isolates were found to be resistant to two or more antimicrobial classes. We were able to document an observed increased in prevalence of Salmonella in PLN during the warmer season, particularly in FF cattle from the southwest region of the US. The mechanisms underlying the observed association between season, region, and production source have yet to be elucidated. Nevertheless, these findings increase our understanding of the sources of contamination of beef products and shed light on

  4. The prognostic relevance of parapyloric lymph node metastasis in Siewert type II/III adenocarcinoma of the esophagogastric junction.

    Science.gov (United States)

    Wang, Jia-Bin; Lin, Man-Qiang; Li, Ping; Xie, Jian-Wei; Lin, Jian-Xian; Lu, Jun; Chen, Qi-Yue; Cao, Long-Long; Lin, Mi; Zheng, Chao-Hui; Huang, Chang-Ming

    2017-12-01

    The purpose of this study was to evaluate the prognosis of patients with Siewert type II/III adenocarcinoma of the esophagogastric junction (AEG) with parapyloric lymph node (No. 5 and 6 lymph nodes, PLN) metastasis and to determine the need for PLN dissection for patients with type II/III AEG. A total of 1008 patients with type II/III AEG who underwent a transabdominal total gastrectomy were enrolled. The long-term surgical outcome of PLN-positive patients and the therapeutic value of PLN dissection were analyzed. There was no significant difference in the incidence of PLN metastasis between type II and III cancers (5.7% vs. 8.5%, P > 0.05). PLN metastasis was a significant prognostic factor for type II/III cancers (HR 1.63; P = 0.001). Among type II/III cancers, the 5-year survival of patients with PLN-positive cancers was much lower than that of patients with PLN-negative cancers (21.3% vs. 60.8%, P  0.05). In the analysis of the therapeutic value of lymph node dissection in each station for type II and III cancers after radical resection, lymph nodes with the lowest therapeutic value index after No. 12a were No. 5 and 6 lymph nodes. Patients with type II/III AEG with PLN metastasis have a poor prognosis, similar to patients with stage IV disease. PLN dissection offers marginal therapeutic value for patients with type II/III AEG. Copyright © 2017 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.

  5. Studi Kasus Kelayakan Penerapan Sistem Hybrid Building Applied Photovoltaics (BAPV-PLN pada Atap Gedung Politeknik Aceh

    Directory of Open Access Journals (Sweden)

    Rachmad Ikhsan

    2017-04-01

    Full Text Available With the undeveloped BAPV(Building Applied Photovoltaics at Office Building and Public Facilities, Caused the high price of solar modules and the lack the economic study on the use of solar modules that housed in the Banda Aceh region. Furthermore, the price of solar modules is expensive, so people think it will cost so much funds to building a BAPV’s system. These problems could be overcomed if the existing technical studies and economic studies of the application of the BAPV’s system. This study aims to assess the application of the BAPV’s system on institutions  building in terms of technical and economic value, in this case the building that is used as the study object is the Polytechnic Aceh’s Building. The method that used in the technical studies are theoretical calculations and simulations using helioscope software, while the methods used for economic studies is using the methods of cost-benefit analysis (cost benefit analysis. The method used to find the NPV (Net Present Value, PP (Payback Period, IRR (Internal Rate of Return, and BCR (Benefit Cost Ratio. If the average value of solar radiation reaching 4.79 kWh / m2 / day and the average daily energy requirement is 592 kWh, the energy generated from BAPV-PLN hybrid system on the roof of the object building will reach the amount of 237 MWh/year with the capacity charge controller used is 7490 A and the capacity of the battery used is 64.487 Ah. Panel tilt angle used is 25o and the type of panel used is Monocrystalline manifold. From the economic value will obtained NPV value of Rp. 20.022.106.937, PP during 5,2 years, IRR of 36% and 3,49 of BCR. Based on the evaluation results of the feasibility study, the project of hybrid BAPV-PLN’s system on the roof of the Polytechnic  Aceh’s  building can be realized, because its already meet the criteria of the feasibility study to make the systems get established in real term.

  6. June 2012 Groundwater Sampling at the Central Nevada Test Area (Data Validation Package)

    International Nuclear Information System (INIS)

    2013-01-01

    The U.S. Department of Energy Office of Legacy Management conducted annual sampling at the Central Nevada Test Area (CNTA) on June 26-27, 2012, in accordance with the 2004 Correction Action Decision Document/Corrective Action Plan for Corrective Action Unit 443: Central Nevada Test Area (CNTA)-Subsurface and the addendum to the 'Corrective Action Decision Document/Corrective Action Plan' completed in 2008. Sampling and analysis were conducted as specified in the Sampling and Analysis Plan for U.S. Department of Energy Office of Legacy Management Sites (LMS/PLN/S04351), continually updated).

  7. May 2011 Groundwater Sampling at the Central Nevada Test Area (Data Validation Package)

    International Nuclear Information System (INIS)

    2011-01-01

    The U.S. Department of Energy Office of Legacy Management conducted annual sampling at the Central Nevada Test Area (CNTA) on May 10-11, 2011, in accordance with the 2004 Correction Action Decision Document/Corrective Action Plan for Corrective Action Unit 443: Central Nevada Test Area (CNTA)-Subsurface and the addendum to the 'Corrective Action Decision Document/Corrective Action Plan' completed in 2008. Sampling and analysis were conducted as specified in the Sampling and Analysis Plan for U.S. Department of Energy Office of Legacy Management Sites (LMS/PLN/S04351), continually updated)

  8. Injectable perlecan domain 1-hyaluronan microgels potentiate the cartilage repair effect of BMP2 in a murine model of early osteoarthritis

    International Nuclear Information System (INIS)

    Srinivasan, Padma P; McCoy, Sarah Y; Yang Weidong; Farach-Carson, Mary C; Kirn-Safran, Catherine B; Jha, Amit K; Jia Xinqiao

    2012-01-01

    The goal of this study was to use bioengineered injectable microgels to enhance the action of bone morphogenetic protein 2 (BMP2) and stimulate cartilage matrix repair in a reversible animal model of osteoarthritis (OA). A module of perlecan (PlnD1) bearing heparan sulfate (HS) chains was covalently immobilized to hyaluronic acid (HA) microgels for the controlled release of BMP2 in vivo. Articular cartilage damage was induced in mice using a reversible model of experimental OA and was treated by intra-articular injection of PlnD1-HA particles with BMP2 bound to HS. Control injections consisted of BMP2-free PlnD1-HA particles, HA particles, free BMP2 or saline. Knees dissected following these injections were analyzed using histological, immunostaining and gene expression approaches. Our results show that knees treated with PlnD1-HA/BMP2 had lesser OA-like damage compared to control knees. In addition, the PlnD1-HA/BMP2-treated knees had higher mRNA levels encoding for type II collagen, proteoglycans and xylosyltransferase 1, a rate-limiting anabolic enzyme involved in the biosynthesis of glycosaminoglycan chains, relative to control knees (PlnD1-HA). This finding was paralleled by enhanced levels of aggrecan in the articular cartilage of PlnD1-HA/BMP2-treated knees. Additionally, decreases in the mRNA levels encoding for cartilage-degrading enzymes and type X collagen were seen relative to controls. In conclusion, PlnD1-HA microgels constitute a formulation improvement compared to HA for efficient in vivo delivery and stimulation of proteoglycan and cartilage matrix synthesis in mouse articular cartilage. Ultimately, PlnD1-HA/BMP2 may serve as an injectable therapeutic agent for slowing or inhibiting the onset of OA after knee injury.

  9. Penentuan Interval Waktu Perawatan Komponen Kritis pada Mesin Turbin di PT PLN (Persero Sektor Pembangkit Ombilin

    Directory of Open Access Journals (Sweden)

    Taufik Taufik

    2016-04-01

    Full Text Available Electrical energy requirements in Indonesia annually increase in line with economic growth and an increase in population. So, PT PLN (Persero have to be able to fulfill the public demands for electrical energy. One of the power generation existed is Steam PowerGeneration. The condition of power generation depended on the maintenance, so, well maintenance made power plant operated at ease condition. Production process in SteamPower Generation of Ombilin used a closed cycle or continuous process. If a machine or an equipment damaged, it will stop the whole function. In the production process, the company involved several main engines are boiler, turbine, condenser, and generator. But the damage often occurs in turbine engine which caused the generation power in Steam PowerGeneration of Ombilin can not operate. Therefore, it needs a maintenance action of machinery/equipment to be able to prevent the damage. The right strategy to keep the engine operating is determining the optimal maintenance interval of equipment for minimizing downtime.The stages of this research begin by determining the critical engine with Criticality Analysis method. Then, the determination of the critical components using Pareto diagram. Then, the determination of the probability density function (pdf and the reliability of critical components. After that, the determination of maintenance intervals of the critical components by using the criterion of minimizing the downtime that will be used to make maintenance scheduling.Based on the processing data has been done, it was found that the critical engine is a turbine engine with a total value is 44 and the critical components of a turbine engine are membrane turbine, bearing and turning gear with the examination time interval for each critical component are 960.48 hours (40 days, 908.57 hours (37 days and 1150.28 hours (48days. While the preventive replacement intervals for components of turbine membrane is after operating for

  10. Preparation of psoralen polymer-lipid hybrid nanoparticles and their reversal of multidrug resistance in MCF-7/ADR cells.

    Science.gov (United States)

    Huang, Qingqing; Cai, Tiange; Li, Qianwen; Huang, Yinghong; Liu, Qian; Wang, Bingyue; Xia, Xi; Wang, Qi; Whitney, John C C; Cole, Susan P C; Cai, Yu

    2018-11-01

    Multidrug resistance (MDR) is the leading cause of failure for breast cancer in the clinic. Thus far, polymer-lipid hybrid nanoparticles (PLN) loaded chemotherapeutic agents has been used to overcome MDR in breast cancer. In this study, we prepared psoralen polymer-lipid hybrid nanoparticles (PSO-PLN) to reverse drug resistant MCF-7/ADR cells in vitro and in vivo. PSO-PLN was prepared by the emulsification evaporation-low temperature solidification method. The formulation, water solubility and bioavailability, particle size, zeta potential and entrapment efficiency, and in vitro release experiments were optimized in order to improve the activity of PSO to reverse MDR. Optimal formulation: soybean phospholipids 50 mg, poly(lactic-co-glycolic) acid (PLGA) 15 mg, PSO 3 mg, and Tween-80 1%. The PSO-PLN possessed a round appearance, uniform size, exhibited no adhesion. The average particle size was 93.59 ± 2.87 nm, the dispersion co-efficient was 0.249 ± 0.06, the zeta potential was 25.47 ± 2.84 mV. In vitro analyses revealed that PSO resistance index was 3.2, and PSO-PLN resistance index was 5.6, indicating that PSO-PLN versus MCF-7/ADR reversal effect was significant. Moreover, PSO-PLN is somewhat targeted to the liver, and has an antitumor effect in the xenograft model of drug-resistant MCF-7/ADR cells. In conclusion, PSO-PLN not only reverses MDR but also improves therapeutic efficiency by enhancing sustained release of PSO.

  11. Transmembrane helix M6 in sarco(endo)plasmic reticulum Ca(2+)-ATPase forms a functional interaction site with phospholamban. Evidence for physical interactions at other sites.

    Science.gov (United States)

    Asahi, M; Kimura, Y; Kurzydlowski, K; Tada, M; MacLennan, D H

    1999-11-12

    In an earlier study (Kimura, Y., Kurzydlowski, K., Tada, M., and MacLennan, D. H. (1997) J. Biol. Chem. 272, 15061-15064), mutation of amino acids on one face of the phospholamban (PLN) transmembrane helix led to loss of PLN inhibition of sarco(endo)plasmic reticulum Ca(2+)-ATPase (SERCA) molecules. This helical face was proposed to form a site of PLN interaction with a transmembrane helix in SERCA molecules. To determine whether predicted transmembrane helices M4, M5, M6, or M8 in SERCA1a interact with PLN, SERCA1a mutants were co-expressed with wild-type PLN and effects on Ca(2+) dependence of Ca(2+) transport were measured. Wild-type inhibitory interactions shifted apparent Ca(2+) affinity of SERCA1a by an average of -0.34 pCa units, but four of the seven mutations in M4 led to a more inhibitory shift in apparent Ca(2+) affinity, averaging -0.53 pCa units. Seven mutations in M5 led to an average shift of -0.32 pCa units and seven mutations in M8 led to an average shift of -0.30 pCa units. Among 11 mutations in M6, 1, Q791A, increased the inhibitory shift (-0.59 pCa units) and 5, V795A (-0.11), L802A (-0.07), L802V (-0.04), T805A (-0.11), and F809A (-0.12), reduced the inhibitory shift, consistent with the view that Val(795), Leu(802), Thr(805), and Phe(809), located on one face of a predicted M6 helix, form a site in SERCA1a for interaction with PLN. Those mutations in M4, M6, or M8 of SERCA1a that enhanced PLN inhibitory function did not enhance PLN physical association with SERCA1a, but mutants V795A and L802A in M6, which decreased PLN inhibitory function, decreased physical association, as measured by co-immunoprecipitation. In related studies, those PLN mutants that gained inhibitory function also increased levels of co-immunoprecipitation of wild-type SERCA1a and those that lost inhibitory function also reduced association, correlating functional interaction sites with physical interaction sites. Thus, both functional and physical data confirm that PLN

  12. Erupce, lávové proudy a nebe plné popela

    Czech Academy of Sciences Publication Activity Database

    Filippi, Michal

    08, Speciál Sopky (2008), s. 90-95 ISSN 1213-1148 Institutional research plan: CEZ:AV0Z30130516 Keywords : volcanic activity * České středohoří Mts. (Czech Republic) * Doupovské hory Mts. Subject RIV: DB - Geology ; Mineralogy

  13. Modulation of cardiac contractility by the phospholamban/SERCA2a regulatome.

    Science.gov (United States)

    Kranias, Evangelia G; Hajjar, Roger J

    2012-06-08

    Heart disease remains the leading cause of death and disability in the Western world. Current therapies aim at treating the symptoms rather than the subcellular mechanisms, underlying the etiology and pathological remodeling in heart failure. A universal characteristic, contributing to the decreased contractile performance in human and experimental failing hearts, is impaired calcium sequestration into the sarcoplasmic reticulum (SR). SR calcium uptake is mediated by a Ca(2+)-ATPase (SERCA2), whose activity is reversibly regulated by phospholamban (PLN). Dephosphorylated PLN is an inhibitor of SERCA and phosphorylation of PLN relieves this inhibition. However, the initial simple view of a PLN/SERCA regulatory complex has been modified by our recent identification of SUMO, S100 and the histidine-rich Ca-binding protein as regulators of SERCA activity. In addition, PLN activity is regulated by 2 phosphoproteins, the inhibitor-1 of protein phosphatase 1 and the small heat shock protein 20, which affect the overall SERCA-mediated Ca-transport. This review will highlight the regulatory mechanisms of cardiac contractility by the multimeric SERCA/PLN-ensemble and the potential for new therapeutic avenues targeting this complex by using small molecules and gene transfer methods.

  14. Imitatio a aemulatio ve Slovníku klementinském

    Czech Academy of Sciences Publication Activity Database

    Voleková, Kateřina

    2010-01-01

    Roč. 133, 3/4 (2010), s. 335-356 ISSN 0024-4457 R&D Projects: GA ČR GAP406/10/1140; GA MŠk(CZ) LC546 Institutional research plan: CEZ:AV0Z90610518 Keywords : Old Czech * medieval lexicography * loan word * calque * medieval Latin-Czech dictionary Subject RIV: AI - Linguistics http://lf.clavmon.cz/LF/Plné%20texty/2010/Voleková_Imitatio.pdf

  15. Cloning and Expression of Plantaricin W Produced by Lactobacillus plantarum U10 Isolate from "Tempoyak" Indonesian Fermented Food as Immunity Protein in Lactococcus lactis.

    Science.gov (United States)

    Lages, Aksar Chair; Mustopa, Apon Zaenal; Sukmarini, Linda; Suharsono

    2015-10-01

    Plantaricins, one of bacteriocin produced by Lactobacillus plantarum, are already known to have activities against several pathogenic bacterium. L. plantarum U10 isolated from "tempoyak," an Indonesian fermented food, produced one kind of plantaricin designated as plantaricin W (plnW). The plnW is suggested as a putative membrane location of protein and has similar conserved motif which is important as immunity to bacteriocin itself. Thus, due to study about this plantaricin, several constructs have been cloned and protein was analyzed in Lactococcus lactis. In this study, plnW gene was successfully cloned into vector NICE system pNZ8148 and created the transformant named L. lactis NZ3900 pNZ8148-WU10. PlnW protein was 25.3 kDa in size. The concentration of expressed protein was significantly increased by 10 ng/mL nisin induction. Furthermore, PlnW exhibited protease activity with value of 2.22 ± 0.05 U/mL and specific activity about 1.65 ± 0.03 U/mg protein with 50 ng/mL nisin induction. Immunity study showed that the PlnW had immunity activity especially against plantaricin and rendered L. lactis recombinant an immunity broadly to other bacteriocins such as pediocin, fermentcin, and acidocin.

  16. ENERGY-DEPENDENT POWER SPECTRAL STATES AND ORIGIN OF APERIODIC VARIABILITY IN BLACK HOLE BINARIES

    International Nuclear Information System (INIS)

    Yu Wenfei; Zhang Wenda

    2013-01-01

    We found that the black hole candidate MAXI J1659–152 showed distinct power spectra, i.e., power-law noise (PLN) versus band-limited noise (BLN) plus quasi-periodic oscillations (QPOs) below and above about 2 keV, respectively, in observations with Swift and the Rossi X-ray Timing Explorer during the 2010 outburst, indicating a high energy cutoff of the PLN and a low energy cutoff of the BLN and QPOs around 2 keV. The emergence of the PLN and the fading of the BLN and QPOs initially took place below 2 keV when the source entered the hard intermediate state and settled in the soft state three weeks later. The evolution was accompanied by the emergence of the disk spectral component and decreases in the amplitudes of variability in the soft and hard X-ray bands. Our results indicate that the PLN is associated with an optically thick disk in both hard and intermediate states, and the power spectral state is independent of the X-ray energy spectral state in a broadband view. We suggest that in the hard or intermediate state, the BLN and QPOs emerge from the innermost hot flow subjected to Comptonization, while the PLN originates from the optically thick disk farther out. The energy cutoffs of the PLN and the BLN or QPOs then follow the temperature of the seed photons from the inner edge of the optically thick disk, while the high frequency cutoff of the PLN follows the orbital frequency of the inner edge of the optically thick disk as well.

  17. CONSTRUCTION, EXPRESSION AND PURIFICATION OF RECOMBINANT PRE-MATURE PEPTIDE OF PLANTARICIN F FROM Lactobacillus plantarum S34 IN Escherichia coli

    Directory of Open Access Journals (Sweden)

    Kusdianawati Kusdianawati

    2015-09-01

    Full Text Available Plantaricin is one of bacteriocins that have the potential to be used as food preservative. Plantaricin is safe for human consumption because it can be easily degraded by proteolytic enzymes. The objective of this study was to express and purify recombinant pre-mature peptide of plantaricin F from Lactobacillus plantarum S34 in Escherichia coli. Plantaricin gene-specific primer was used to obtain pln F structural gene amplicon from L. plantarum S34. This amplicon was cloned in pET32a vector and expressed in E. coli BL21 (DE3 pLysS. Pre-mature plantaricin F peptide was expressed as Histagged-fusion protein and separated by Co2+-chelating affinity chromatography. L. plantarum S34-derived pre-mature plantaricin F peptide fused with thioredoxin-(His6tag had successfully been expressed in E. coli BL21 (DE3 pLysS using pET32a as an expression vector. The fused recombinant pln F as pre-mature state expressed had a molecular mass of +24 kDa, meanwhile the fused recombinant that contained only the leader peptide of pln F appeared as +20 kDa based on SDS-PAGE separations. The optimal production of fused recombinant pln F as soluble fraction was obtained when culture condition was added with 0.5 mM of IPTG and incubated at 22°C for 5 hours (OD~1. Furthermore, the expression of fused recombinant pln F as its pre-mature peptide pointed out that the pln F’s leader peptide could be proteolytically cleaved by a system in heterologous cells. Overall, heterologous pln F production as pre-mature peptide fused with thioredoxin-(His6tag had been well established. From this research, we expect plantaricin F can be expressed and purified in E. coli.

  18. Diagnostic efficacy of ultrasound-guided core-needle biopsy of peripheral lymph nodes in sarcoidosis.

    Science.gov (United States)

    Boussouar, S; Medjhoul, A; Bernaudin, J F; Tayebjee, O; Soussan, M; Uzunhan, Y; Nunes, H; Kambouchner, M; Martin, A; Valeyre, D; Brillet, P Y

    2015-09-14

    Core-needle biopsy guided by ultrasound can be performed for investigating peripheral lymph node (PLN). The aim of this study was to determine the efficacy of this technique in sarcoidosis. Retrospective review of files of all patients in the database of the radiology department of Avicenne university hospital who underwent PLN biopsies guided by ultrasound from January 2008 to June 2011 (n=292). Cases with either granulomas at histology with the procedure or with a final diagnosis of sarcoidosis were included in the study. The histological specimens were adequate in 282 out of 292 cases (96%) showing non-caseating granulomas in 22 cases (n=20 patients with a final diagnosis of sarcoidosis and n=2 patients with tuberculosis). After reviewing clinical files of the 282 patient, 22 were confirmed to have sarcoidosis, at initial presentation (n=19) or later during flare-up or relapse (n=3) with only 2 patients having no granuloma on PLN biopsy. PLN were palpable in 18 cases and only detected by (18F)FDG-PET/CT showing increased PLN uptake in 4 cases. The sensitivity and specificity of adequate biopsy were 91 and 99% and the positive and negative predictive values were 91 and 99%, respectively. Core-needle biopsy guided by ultrasound has a high efficacy for evidencing granulomas in sarcoidosis patients with PLN involvement either clinically palpable or in the presence of (18F)FDG-PET/CT uptake.

  19. GenBank blastn search result: AK063155 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK063155 001-111-H11 X12844.1 Rice chloroplast DNA short interspersed repeat (pCt-3) upstream... rpl2 gene ( also present in mitDNA downstream rbcL gene).|PLN PLN 2e-28 Plus Plus ...

  20. GenBank blastn search result: AK106868 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK106868 002-118-D05 AF335504.1 Oryza sativa (japonica cultivar-group) hemoglobin 1 (hb1), hemoglobin... 3 (hb3), and hemoglobin 4 (hb4) genes, complete cds.|PLN PLN 4e-13 Plus Minus ...

  1. GenBank blastn search result: AK109468 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK109468 001-128-C06 AF335504.1 Oryza sativa (japonica cultivar-group) hemoglobin 1 (hb1), hemoglobin... 3 (hb3), and hemoglobin 4 (hb4) genes, complete cds.|PLN PLN 2e-24 Plus Minus ...

  2. GenBank blastn search result: AK064054 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK064054 001-125-F02 AF335504.1 Oryza sativa (japonica cultivar-group) hemoglobin 1 (hb1), hemoglobin... 3 (hb3), and hemoglobin 4 (hb4) genes, complete cds.|PLN PLN 1e-179 Plus Plus ...

  3. GenBank blastn search result: AK073899 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK073899 J033072H18 AF335504.1 Oryza sativa (japonica cultivar-group) hemoglobin 1 (hb1), hemoglobin... 3 (hb3), and hemoglobin 4 (hb4) genes, complete cds.|PLN PLN 1e-106 Plus Minus ...

  4. GenBank blastn search result: AK060730 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK060730 001-032-A03 AF335504.1 Oryza sativa (japonica cultivar-group) hemoglobin 1 (hb1), hemoglobin... 3 (hb3), and hemoglobin 4 (hb4) genes, complete cds.|PLN PLN 5e-17 Plus Minus ...

  5. Prognostic Significance of Nodal Location and Ratio in Stage IIIC Endometrial Carcinoma Among a Multi-Institutional Academic Collaboration.

    Science.gov (United States)

    Mayadev, Jyoti; Elshaikh, Mohamed A; Christie, Alana; Nagel, Christa; Kennedy, Vanessa; Khan, Nadia; Lea, Jayanthi; Ghanem, Ahmad; Miller, David; Xie, Xian-Jin; Folkert, Michael; Albuquerque, Kevin

    2018-04-20

    Stage IIIC endometrial carcinoma (EC) represents pathologically heterogenous patients with single/multiple pelvic (stage IIIC1) or paraaortic (stage IIIC2) lymph nodes (LNs). There is an increasing trend to offer adjuvant chemotherapy (CT) +/- radiation (RT) uniformly to these patients, regardless of substage. We investigate the prognostic significance of positive LN (pLN) number, ratio (%pLN), location (IIC1 vs. IIC2), and adjuvant treatment on patterns of failure and survival in a large collaborative multi-institutional series. Clinical data for stage III EC patients such as patient characteristics, surgery/pathologic details, adjuvant therapies (including CT, RT, and chemotherapy and radiation), and outcomes (including pelvic control [PC], disease-free survival [DFS], distant DFS, and overall survival [OS]) were collected from 3 academic institutions. Log-rank analyses, Cox regression univariate and multivariate analyses were performed. Of the 264 patients queried for stage III disease, 237 (73%) had pLN, and complete LN sampling for analysis. The mean number of pLN in the combined data were 3.9, with 26.1% of all LN sampled positive; 121 patients (51%) staged IIIC1, and 116 patients (49%) staged IIIC2. There was a significant difference in number of pLN (P=0.0006) and total LN sampled by institution (range, 13 to 35; P=0.0004), without a difference in %pLN (P=0.35). Ninety-seven of 220 (44.1%) have ≥20% pLN. While controlling for substage and institution, a decrease in DFS (hazard ratio [HR], 1.1; P=0.007), and OS (HR, 1.1; P=0.01) was observed with every increase of 10% in the pLN ratio. There was a significant difference in DFS (HR, 1.8; P=0.003), PC (HR, 1.9; P=0.004), and distant DFS (HR, 1.6; P=0.03), as well as a trend for decreased OS (HR, 1.6; P=0.08) for substage IIIC2 versus IIIC1 disease; 5 years DFS 40% versus 45%, OS 50% versus 57%. Patients received no adjuvant therapy (10%), CT alone (27%), RT alone (16%), or chemotherapy and radiation (47

  6. GenBank blastx search result: AK104002 [KOME

    Lifescience Database Archive (English)

    Full Text Available opy of the insertion element IS2 is inserted after cloning in E.coli by duplicating a 5 base pair sequence. This is the wildtype TRP5 gene before insertion of IS2.|PLN PLN 6e-22 +1 ...

  7. Endoplasmic reticulum protein targeting of phospholamban: a common role for an N-terminal di-arginine motif in ER retention?

    Directory of Open Access Journals (Sweden)

    Parveen Sharma

    2010-07-01

    Full Text Available Phospholamban (PLN is an effective inhibitor of the sarco(endoplasmic reticulum Ca(2+-ATPase, which transports Ca(2+ into the SR lumen, leading to muscle relaxation. A mutation of PLN in which one of the di-arginine residues at positions 13 and 14 was deleted led to a severe, early onset dilated cardiomyopathy. Here we were interested in determining the cellular mechanisms involved in this disease-causing mutation.Mutations deleting codons for either or both Arg13 or Arg14 resulted in the mislocalization of PLN from the ER. Our data show that PLN is recycled via the retrograde Golgi to ER membrane traffic pathway involving COP-I vesicles, since co-immunoprecipitation assays determined that COP I interactions are dependent on an intact di-arginine motif as PLN RDelta14 did not co-precipitate with COP I containing vesicles. Bioinformatic analysis determined that the di-arginine motif is present in the first 25 residues in a large number of all ER/SR Gene Ontology (GO annotated proteins. Mutations in the di-arginine motif of the Sigma 1-type opioid receptor, the beta-subunit of the signal recognition particle receptor, and Sterol-O-acyltransferase, three proteins identified in our bioinformatic screen also caused mislocalization of these known ER-resident proteins.We conclude that PLN is enriched in the ER due to COP I-mediated transport that is dependent on its intact di-arginine motif and that the N-terminal di-arginine motif may act as a general ER retrieval sequence.

  8. Anti-Myeloperoxidase Antibodies Associate with Future Proliferative Lupus Nephritis

    Directory of Open Access Journals (Sweden)

    S. W. Olson

    2017-01-01

    Full Text Available Background. The subclinical pathophysiology of proliferative lupus nephritis (PLN has not been fully elucidated. Myeloperoxidase anti-neutrophil cytoplasmic antibody (MPO-ANCA is associated with PLN, but prediagnostic levels have not been reported. Methods. We performed a retrospective case-control Department of Defense Serum Repository (DoDSR study comparing MPO-ANCA levels in longitudinal prediagnostic serum samples for 23 biopsy confirmed proliferative lupus nephritis (PLN patients to DoDSR identified age, sex, race, and age of serum matched healthy and SLE without LN disease controls. We also compared the temporal relationship of MPO-ANCA to anti-double stranded DNA antibodies (dsDNAab. Results. A greater proportion of PLN patients had prediagnostic MPO-ANCA levels above ≥3 U/mL and ≥6 U/mL compared to SLE without LN (91% versus 43%, p<0.001; 57% versus 5%, p<0.001, resp.. In subgroup analysis, the MPO-ANCA threshold of ≥3 U/mL was significant at <1 year (88% versus 39%, p=0.007 and 1–4 years (87% versus 38%, p=0.009 prior to diagnosis. Statistically significant subclinical MPO-ANCA levels (≥3 U/mL occurred prior to statistically significant dsDNAab ≥ 3 IU/ml (89% versus 11%, p=0.003. Conclusions. Subclinical MPO-ANCA levels could distinguish future PLN from SLE without LN. MPO-ANCA manifests prior to clinical disease and subclinical dsDNAab to suggest that it may contribute directly to PLN pathogenicity.

  9. Reliability-Based Performance Assessment of Damaged Ships

    Science.gov (United States)

    2006-10-01

    37OR.A 2 AceI 2 oce 3 3C7R Main Deck Plan View at 9.906 metre STAA T~SIc ACCa IC 111 tI RO MAO ’ 2 0004 M 3O m 3 STORES) me 3 1 002~s STOR1 PfIS PlnVIS...Vol. 15, pp.7 4 -9 3 . Kaplan , M. Benatar, M., Bentson, J., Achtarides, T.A. (1984). "Analysis and assessment of major uncertainties associated with

  10. Contribution of the Tyr-1 in Plantaricin149a to Disrupt Phospholipid Model Membranes

    Directory of Open Access Journals (Sweden)

    Georgina Tonarelli

    2013-06-01

    Full Text Available Plantaricin149a (Pln149a is a cationic antimicrobial peptide, which was suggested to cause membrane destabilization via the carpet mechanism. The mode of action proposed to this antimicrobial peptide describes the induction of an amphipathic α-helix from Ala7 to Lys20, while the N-terminus residues remain in a coil conformation after binding. To better investigate this assumption, the purpose of this study was to determine the contributions of the Tyr1 in Pln149a in the binding to model membranes to promote its destabilization. The Tyr to Ser substitution increased the dissociation constant (KD of the antimicrobial peptide from the liposomes (approximately three-fold higher, and decreased the enthalpy of binding to anionic vesicles from −17.2 kcal/mol to −10.2 kcal/mol. The peptide adsorption/incorporation into the negatively charged lipid vesicles was less effective with the Tyr1 substitution and peptide Pln149a perturbed the liposome integrity more than the analog, Pln149S. Taken together, the peptide-lipid interactions that govern the Pln149a antimicrobial activity are found not only in the amphipathic helix, but also in the N-terminus residues, which take part in enthalpic contributions due to the allocation at a lipid-aqueous interface.

  11. Salmonella in peripheral lymph nodes of healthy cattle at slaughter

    Science.gov (United States)

    To more fully characterize the burden of Salmonella enterica in bovine peripheral lymph nodes (PLN), PLN (n=5,450) were collected from healthy cattle at slaughter in 12 commercial abattoirs that slaughtered feedlot-fattened (FF) cattle exclusively (n=7), cattle removed (or culled) from breeding herd...

  12. PERLINDUNGAN HUKUM KONSUMEN LISTRIK PRABAYAR DI MAGELANG

    Directory of Open Access Journals (Sweden)

    Siti Vickie Dina Maulaya Adhiansyah

    2018-01-01

    Full Text Available Along with the development of technology, PT. PLN (Persero has developed a product called "Prepaid Electricity".Prepaid electricity PT.PLN a new service for customers to manage power consumption,that came into effect in 2008. In the course of pre-paid electricity it turns out there is still a shortage of electricity that causes consumer complaints in Magelang. Based on the existing background, the authors are interested in researching it.The problem of this thesis research is:1 How is the agreement between the electrical installation of prepaid electricity in Magelang, (2 How does the legal protection prepaid electricity consumers in Magelang, (3 What efforts were made by consumers of electricity when harmed in the use of prepaid electricity in Magelang.The method used in the preparation of this paper uses normative juridical approach. The research material used by the authors consisted of primary legal materials, secondary and tertiary.The data used is secondary data, research specifications is a research-analytical description. This study using purposive sampling method with the research tools shaped open questionnaire respondents as many as 25 people in the area of prepaid electricity consumers Magelang, interviews with officials of PLN Area Magelang and related parties.Based on the research results showed that the electricity trading mechanism consists of a new installation of electric power, electric power changes and migration electricity. Legal protection prepaid electricity include: (1 The Power Purchase Agreement (SPJBTL, these agreements can be categorized as a standard contract.If the terms of consumer protection laws, clauses in SPJBTL still containing the exoneration clause, thus infringing the rights of consumers,2Prepaid electricity rates are more expensive than postpaid electricity, this is caused by the electrical installation is not appropriate. Another factor that is coming into effect of the tariff adjustment is affected by

  13. Next Generation Nuclear Plant Intermediate Heat Exchanger Materials Research and Development Plan (PLN-2804)

    Energy Technology Data Exchange (ETDEWEB)

    J. K. Wright

    2008-04-01

    DOE has selected the High Temperature Gas-cooled Reactor (HTGR) design for the Next Generation Nuclear Plant (NGNP) Project. The NGNP will demonstrate the use of nuclear power for electricity and hydrogen production. It will have an outlet gas temperature in the range of 900°C and a plant design service life of 60 years. The reactor design will be a graphite moderated, helium-cooled, prismatic or pebble-bed reactor and use low-enriched uranium, Tri-Isotopic (TRISO)-coated fuel. The plant size, reactor thermal power, and core configuration will ensure passive decay heat removal without fuel damage or radioactive material releases during accidents. The NGNP Materials Research and Development (R&D) Program is responsible for performing R&D on likely NGNP materials in support of the NGNP design, licensing, and construction activities. Today’s high-temperature alloys and associated ASME Codes for reactor applications are approved up to 760°C. However, some primary system components, such as the Intermediate Heat Exchanger (IHX) for the NGNP will require use of materials that can withstand higher temperatures. The thermal, environmental, and service life conditions of the NGNP will make selection and qualification of some high-temperature materials a significant challenge. Examples include materials for the core barrel and core internals, such as the control rod sleeves. The requirements of the materials for the IHX are among the most demanding. Selection of the technology and design configuration for the NGNP must consider both the cost and risk profiles to ensure that the demonstration plant establishes a sound foundation for future commercial deployments. The NGNP challenge is to achieve a significant advancement in nuclear technology while at the same time setting the stage for an economically viable deployment of the new technology in the commercial sector soon after 2020. A number of solid solution strengthened nickel based alloys have been considered for application in heat exchangers and core internals for the NGNP. The primary candidates are Inconel 617, Haynes 230, Incoloy 800H and Hastelloy XR. Based on the technical maturity, availability in required product forms, experience base, and high temperature mechanical properties all of the vendor pre-conceptual design studies have specified Alloy 617 as the material of choice for heat exchangers. Also a draft code case for Alloy 617 was developed previously. Although action was suspended before the code case was accepted by ASME, this draft code case provides a significant head start for achieving codification of the material. Similarly, Alloy 800H is the material of choice for control rod sleeves. In addition to the above listed considerations, Alloy 800H is already listed in the nuclear section of the ASME Code; although the maximum use temperature and time need to be increased.

  14. Building Healthy Start Grantees' Capacity to Achieve Collective Impact: Lessons from the Field.

    Science.gov (United States)

    Bradley, Kimberly; Chibber, Karuna S; Cozier, Naima; Meulen, Peggy Vander; Ayres-Griffin, Colleen

    2017-12-01

    Purpose While Healthy Start has emphasized the need for multi-sectorial community engagement and collaboration since its inception, in 2014 Healthy Start adopted Collective Impact (CI) as a framework for reducing infant mortality. This paper describes the development of a peer-focused capacity-building strategy that introduced key elements of CI and preliminary findings of Healthy Start grantees' progress with using CI as an approach to collaboration. Description The Collective Impact Peer Learning Networks (CI-PLNs) consisted of eight 90-min virtual monthly meetings and one face-to-face session that reviewed CI pre-conditions and conditions. Evaluation sources included: a facilitated group discussion at the final CI-PLN exploring grantee CI and CAN accomplishments (n = 57); routine evaluations (n = 144 pre, 46 interim, and 40 post PLN) examining changes in knowledge and practices regarding CI; and post CI-PLN implementation, three in-depth interviews with grantees who volunteered to discuss their experience with CI and participation in the CI-PLN. Assessment CI-PLN participants reported increased knowledge and confidence in the application of CI. Several participants reported that the CI-PLN created a space for engaging in peer sharing challenges, successes, and best practices. Participants also reported a desire to continue implementing CI and furthering their learning. Conclusion The CI-PLNs met the initial goal of increasing Healthy Start grantees' understanding of CI and determining the initial focus of their efforts. By year five, the EPIC Center anticipates Healthy Start CANs will have a sustainable infrastructure in place that supports the established common agenda, shared measures, and ongoing and meaningful inclusion of community members.

  15. January 2012 Groundwater Sampling at the Gnome-Coach, New Mexico, Site (Data Validation Package)

    Energy Technology Data Exchange (ETDEWEB)

    Findlay, Richard C. [S.M. Stoller Corporation, Broomfield, CO (United States)

    2012-12-01

    Annual sampling was conducted January 18, 2012, to monitor groundwater for potential radionuclide contamination at the Gnome-Coach site in New Mexico. The sampling was performed as specified in the Sampling and Analysis Plan for U.S. Department of Energy Office of Legacy Management Sites (LMS/PLN/S04351, continually updated). Well LRL-7 was not sampled per instruction from the lead. A duplicate sample was collected from well USGS-1 and water levels were measured in the monitoring wells onsite.

  16. January 2012 Groundwater Sampling at the Gnome-Coach, New Mexico, Site (Data Validation Package)

    International Nuclear Information System (INIS)

    2012-01-01

    Annual sampling was conducted January 18, 2012, to monitor groundwater for potential radionuclide contamination at the Gnome-Coach site in New Mexico. The sampling was performed as specified in the Sampling and Analysis Plan for U.S. Department of Energy Office of Legacy Management Sites (LMS/PLN/S04351, continually updated). Well LRL-7 was not sampled per instruction from the lead. A duplicate sample was collected from well USGS-1 and water levels were measured in the monitoring wells onsite.

  17. January 2011 Groundwater Sampling at the Gnome-Coach, New Mexico, Site (Data Validation Package)

    International Nuclear Information System (INIS)

    2011-01-01

    Annual sampling was conducted January 19, 2011, to monitor groundwater for potential radionuclide contamination at the Gnome-Coach site in New Mexico. The sampling was performed as specified in the Sampling and Analysis Plan for U.S. Department of Energy Office of Legacy Management Sites (LMS/PLN/S04351, continually updated). Well LRL-7 was not sampled per instruction from the lead. A duplicate sample was collected from well USGS-1.Water levels were measured in the monitoring wells onsite.

  18. New insights into the burden and costs of multiple sclerosis in Europe: Results for Poland.

    Science.gov (United States)

    Selmaj, Krzysztof; Kobelt, Gisela; Berg, Jenny; Orlewska, Ewa; Capsa, Daniela; Dalén, Johan

    2017-08-01

    In order to estimate the value of interventions in multiple sclerosis (MS) - where lifetime costs and outcomes cannot be observed - outcome data have to be combined with costs. This requires that cost data be regularly updated. This study is part of a cross-sectional retrospective study in 16 European countries collecting current data on resource consumption, work capacity, health-related quality of life (HRQoL) and prevalent symptoms for patients with MS. Descriptive analyses are presented by level of severity, from the societal perspective, in 2015 Polish Zloty (PLN). A total of 411 MS patients (mean age = 40 years) participated in Poland; 94% were below retirement age, and of these, 59% were employed. Employment was related to disability, and MS affected productivity for 85% of those working. Overall, 97% and 71% of patients experienced fatigue and cognition as important problems, respectively. Mean utility and total annual costs were 0.686 and 48,700 PLN at Expanded Disability Status Scale (EDSS) 0-3, 0.521 and 59,200 PLN at EDSS 4-6.5 and 0.208 and 81,600 PLN at EDSS 7-9, respectively. The average cost of a relapse was 3,900 PLN. This study illustrates the burden of MS on Polish patients and provides current data that are important for developing health policies.

  19. Elevated Subclinical Double-Stranded DNA Antibodies and Future Proliferative Lupus Nephritis

    Science.gov (United States)

    Lee, Jessica J.; Prince, Lisa K.; Baker, Thomas P.; Papadopoulos, Patricia; Edison, Jess; Abbott, Kevin C.

    2013-01-01

    Summary Background and objectives Elevated anti–double-stranded DNA (dsDNA) antibody and C-reactive protein are associated with proliferative lupus nephritis (PLN). Progression of quantitative anti-dsDNA antibody in patients with PLN has not been compared with that in patients with systemic lupus erythematosus (SLE) without LN before diagnosis. The temporal relationship between anti-dsDNA antibody and C-reactive protein elevation has also not been evaluated. Design, setting, participants, & measurements This case-control Department of Defense Serum Repository (established in 1985) study compared longitudinal prediagnostic quantitative anti-dsDNA antibody and C-reactive protein levels in 23 patients with biopsy-proven PLN (Walter Reed Army Medical Center, 1993–2009) with levels in 21 controls with SLE but without LN matched for patient age, sex, race, and age of serum sample. The oldest (median, 2601 days; 25%, 1245 days, 75%, 3075 days), the second to last (368; 212, 635 days), and the last (180; 135, 477 days) serum sample before diagnosis were analyzed. Results More patients with PLN had an elevated anti-dsDNA antibody level than did the matched controls at any point (78% versus 5%; P4 years (33% versus 0%; P=0.04) before diagnosis. A rate of increase >1 IU/ml per year (70% versus 0%; P<0.001) was most specific for PLN. The anti-dsDNA antibody levels increased before C-reactive protein did in most patients with an antecedent elevation (92% versus 8%; P<0.001). Conclusions Elevated anti-dsDNA antibody usually precedes both clinical and subclinical evidence of proliferative LN, which suggests direct pathogenicity. Absolute anti-dsDNA antibody level and rate of increase could better establish risk of future PLN in patients with SLE. PMID:23833315

  20. Time course of myosin heavy chain transitions in neonatal rats: importance of innervation and thyroid state

    Science.gov (United States)

    Adams, G. R.; McCue, S. A.; Zeng, M.; Baldwin, K. M.

    1999-01-01

    During the postnatal period, rat limb muscles adapt to weight bearing via the replacement of embryonic (Emb) and neonatal (Neo) myosin heavy chains (MHCs) by the adult isoforms. Our aim was to characterize this transition in terms of the six MHC isoforms expressed in skeletal muscle and to determine the importance of innervation and thyroid hormone status on the attainment of the adult MHC phenotype. Neonatal rats were made hypothyroid via propylthiouracil (PTU) injection. In normal and PTU subgroups, leg muscles were unilaterally denervated at 15 days of age. The MHC profiles of plantaris (PLN) and soleus (Sol) muscles were determined at 7, 14, 23, and 30 days postpartum. At day 7, the Sol MHC profile was 55% type I, 30% Emb, and 10% Neo; in the PLN, the pattern was 60% Neo and 25% Emb. By day 30 the Sol and PLN had essentially attained an adult MHC profile in the controls. PTU augmented slow MHC expression in the Sol, whereas in the PLN it markedly repressed IIb MHC by retaining neonatal MHC expression. Denervation blunted the upregulation of IIb in the PLN and of Type I in the Sol and shifted the pattern to greater expression of IIa and IIx MHCs in both muscles. In contrast to previous observations, these findings collectively suggest that both an intact thyroid and innervation state are obligatory for the attainment of the adult MHC phenotype, particularly in fast-twitch muscles.

  1. Prakiraan Beban Listrik Jangka Pendek Kota Banda Aceh Berbasis Logika Fuzzy

    OpenAIRE

    Syukriyadin,; Syahputra, Rio

    2012-01-01

    One of the technical aspects that support the optimal operation planning of a power plant when viewed in terms of system reliability and economic is about short-term load forecasting. The objective of this research is to forcasting hourly short-term electric load peak (17:30 to 22:30 GMT) at loading area of Transmission Distribution Banda Aceh Unit of PT. PLN P3B Aceh 150-20 kV by using Adaptive Neuro Fuzzy Inference System (ANFIS) method. The toolbox used to predict short-term electric load ...

  2. Instrument Qualification of Custom Fabricated Water Activity Meter for Hot Cell Use

    Energy Technology Data Exchange (ETDEWEB)

    McCoskey, Jacob K. [Hanford Site (HNF), Richland, WA (United States)

    2014-01-22

    This report describes a custom fabricated water activity meter and the results of the qualification of this meter as described in the laboratory test plan LAB-PLN-11-00012, Testing and Validation of an Enhanced Acquisition and Control System. It was calibrated against several NaOH solutions of varying concentrations to quantify the accuracy and precision of the instrument at 20 °C and 60 °C. Also, a schematic and parts list of the equipment used to make the water activity meter will be presented in this report.

  3. N0/N1, PNL, or LNR? The effect of lymph node number on accurate survival prediction in pancreatic ductal adenocarcinoma.

    Science.gov (United States)

    Valsangkar, Nakul P; Bush, Devon M; Michaelson, James S; Ferrone, Cristina R; Wargo, Jennifer A; Lillemoe, Keith D; Fernández-del Castillo, Carlos; Warshaw, Andrew L; Thayer, Sarah P

    2013-02-01

    We evaluated the prognostic accuracy of LN variables (N0/N1), numbers of positive lymph nodes (PLN), and lymph node ratio (LNR) in the context of the total number of examined lymph nodes (ELN). Patients from SEER and a single institution (MGH) were reviewed and survival analyses performed in subgroups based on numbers of ELN to calculate excess risk of death (hazard ratio, HR). In SEER and MGH, higher numbers of ELN improved the overall survival for N0 patients. The prognostic significance (N0/N1) and PLN were too variable as the importance of a single PLN depended on the total number of LN dissected. LNR consistently correlated with survival once a certain number of lymph nodes were dissected (≥13 in SEER and ≥17 in the MGH dataset). Better survival for N0 patients with increasing ELN likely represents improved staging. PLN have some predictive value but the ELN strongly influence their impact on survival, suggesting the need for a ratio-based classification. LNR strongly correlates with outcome provided that a certain number of lymph nodes is evaluated, suggesting that the prognostic accuracy of any LN variable depends on the total number of ELN.

  4. Cost intensity of identifying contraindications to driving a company car through psychological tests on the basis of real-world data in Poland.

    Science.gov (United States)

    Juszczyk, Grzegorz; Czerw, Aleksandra; Tatara, Tomasz; Duda-Zalewska, Aneta; Walusiak-Skorupa, Joanna; Słoniewski, Robert; Staniszewska, Anna; Olejniczak, Dominik; Religioni, Urszula

    2017-12-01

    The study objective was to determine the cost intensity of identifying contraindications to fleet car driving in preventive care. The objective of a psychological examination is to identify impaired psychomotor function as well as any intellectual, cognitive or emotional incapacities, which may seriously impede safety. Real-world data were collected from the healthcare provider in Poland. A total of 8111 anonymous records from psychomotor tests performed between January 1 and December 31, 2012 were analysed. The number needed to screen to identify one person with contraindications to driving was 737. An individual examination costs PLN 150, thus the estimated cost of identifying one case was PLN 110,550 (EUR 25,000). The average number of tests in a small enterprise with 20-50 fleet cars was estimated at 5-25 in a 5-year period and their cost at PLN 3750 (PLN 750 annually). Health check-ups include ophthalmological and neurological consultations; therefore, psychological examination of fleet car drivers may be considered excessive due to cost and limited preventive value. High costs may be burdensome mainly to larger companies. A final decision regarding necessity of psychological testing should be preceded by medical assessment of the risk of work accidents.

  5. Direct healthcare costs and cost-effectiveness of acute coronary syndrome secondary prevention with ticagrelor compared to clopidogrel: economic evaluation from the public payer's perspective in Poland based on the PLATO trial results.

    Science.gov (United States)

    Pawęska, Justyna; Macioch, Tomasz; Perkowski, Piotr; Budaj, Andrzej; Niewada, Maciej

    2014-01-01

    Ticagrelor is the first reversibly binding oral P2Y12 receptor antagonist designed to reduce clinical thrombotic events in patients with acute coronary syndrome (ACS). Compared to clopidogrel, ticagrelor has been proven to significantly reduce the rate of death from vascular causes, myocardial infarction (MI), or stroke without an increase in the rate of overall major bleeding in patients who have an ACS with or without ST-segment elevation (STEMI and NSTEMI) or unstable angina (UA). To evaluate the cost-effectiveness and healthcare costs associated with secondary prevention of ACS using ticagrelor or clopidogrel in patients after STEMI, NSTEMI and UA. An economic model based on results from the PLATO trial was used to evaluate the cost-effectiveness of one-year therapy with ticagrelor or clopidogrel. The structure of the model consisted of two parts, i.e. the decision tree with one-year PLATO results and the Markov model with lifelong estimations, which exceeded PLATO follow-up data. The model was adjusted to Polish settings with country-specific data on death rates in the general population and direct medical costs calculated from the public payer's perspective. Costs were derived from the National Health Fund (NHF) and the Ministry of Health and presented in PLN 2013 values. Annual mean costs of second and subsequent years after stroke or MI were obtained from the literature. Uncertainty of assumed parameters was tested in scenarios and probabilistic sensitivity analyses. The adopted model allowed the estimation of an incremental cost-effectiveness ratio for life years gained (LYG) and an incremental cost-utility ratio for quality adjusted life years (QALY). Total direct medical costs to the public payer at a one year horizon were 2,905 PLN higher with ticagrelor than with clopidogrel. However, mean healthcare costs at a one year horizon (excluding drug costs and concomitant drugs) were 690 PLN higher for patients treated with clopidogrel. In a lifetime horizon

  6. An investigation into the population abundance distribution of mRNAs, proteins, and metabolites in biological systems.

    Science.gov (United States)

    Lu, Chuan; King, Ross D

    2009-08-15

    Distribution analysis is one of the most basic forms of statistical analysis. Thanks to improved analytical methods, accurate and extensive quantitative measurements can now be made of the mRNA, protein and metabolite from biological systems. Here, we report a large-scale analysis of the population abundance distributions of the transcriptomes, proteomes and metabolomes from varied biological systems. We compared the observed empirical distributions with a number of distributions: power law, lognormal, loglogistic, loggamma, right Pareto-lognormal (PLN) and double PLN (dPLN). The best-fit for mRNA, protein and metabolite population abundance distributions was found to be the dPLN. This distribution behaves like a lognormal distribution around the centre, and like a power law distribution in the tails. To better understand the cause of this observed distribution, we explored a simple stochastic model based on geometric Brownian motion. The distribution indicates that multiplicative effects are causally dominant in biological systems. We speculate that these effects arise from chemical reactions: the central-limit theorem then explains the central lognormal, and a number of possible mechanisms could explain the long tails: positive feedback, network topology, etc. Many of the components in the central lognormal parts of the empirical distributions are unidentified and/or have unknown function. This indicates that much more biology awaits discovery.

  7. Coculture-inducible bacteriocin activity of Lactobacillus plantarum strain J23 isolated from grape must.

    Science.gov (United States)

    Rojo-Bezares, Beatriz; Sáenz, Yolanda; Navarro, Laura; Zarazaga, Myriam; Ruiz-Larrea, Fernanda; Torres, Carmen

    2007-08-01

    Detection and characterization of bacteriocin production by Lactobacillus plantarum strain J23, recovered from a grape must sample in Spain, have been carried out. Bacteriocin activity was degraded by proteolytic enzymes (trypsin, alfa-chymotrypsin, papaine, protease, proteinase K and acid proteases), and it was stable at high temperatures (121 degrees C, 20min), in a wide range of pH (1-12), and after treatment with organic solvents. L. plantarum J23 showed antimicrobial activity against Oenococcus oeni, and a range of Lactobacillus and Pediococcus species. Bacteriocin production was detected in liquid media only when J23 was cocultivated with some inducing bacteria, and induction took place when intact cells or 55 degrees C heated cells of the inducer were cocultivated with J23, but not with their autoclaved cells. Bacteriocin activity of J23 was not induced by high initial J23 inocula, and it was detected in cocultures during the exponential phase. The presence of ethanol or acidic pH in the media reduced bacteriocin production in the cocultures of J23 with the inducing bacteria. The presence of plantaricin-related plnEF and plnJ genes was detected by PCR and sequencing. Nevertheless, negative results were obtained for plnA, plnK, plNC8, plS and plW genes.

  8. How much is a bee worth? Economic aspects of pollination of selected crops in Poland

    Directory of Open Access Journals (Sweden)

    Marcin Zych

    2012-12-01

    Full Text Available Scientific studies state that a considerable part of the economic value of crop plant production should be attributed to the free services of pollinating insects. Such calculations are available for several EU and North American countries, and the present paper evaluates the value of pollination services to 19 important Polish crop plants. It is estimated that the market value of 19 entomogamous crops reaches the sum of approx. 7.5 billion PLN (thousand million (approx. 1.8 billion EUR, 39% of this may be attributed to the insect activities, the most important being bees (the service value of approx. 2.5 billion PLN/0.6 billion EUR and dipterans (almost 0.3 billion PLN/ 74 billion EUR. The paper discusses also the challenges and pitfalls of similar estimations and the need for conservation actions directed on crop plant pollinators.

  9. Similarity of recombinant human perlecan domain 1 by alternative expression systems bioactive heterogenous recombinant human perlecan D1

    DEFF Research Database (Denmark)

    Ellis, April L; Pan, Wensheng; Yang, Guang

    2010-01-01

    BACKGROUND: Heparan sulfate glycosaminoglycans are diverse components of certain proteoglycans and are known to interact with growth factors as a co-receptor necessary to induce signalling and growth factor activity. In this report we characterize heterogeneously glycosylated recombinant human...... perlecan domain 1 (HSPG2 abbreviated as rhPln.D1) synthesized in either HEK 293 cells or HUVECs by transient gene delivery using either adenoviral or expression plasmid technology. RESULTS: By SDS-PAGE analysis following anion exchange chromatography, the recombinant proteoglycans appeared to possess...... glycosaminoglycan chains ranging, in total, from 6 kDa to >90 kDa per recombinant. Immunoblot analysis of enzyme-digested high Mr rhPln.D1 demonstrated that the rhPln.D1 was synthesized as either a chondroitin sulfate or heparan sulfate proteoglycan, in an approximately 2:1 ratio, with negligible hybrids. Secondary...

  10. Analisa Penggunaan Recloser untuk Pengaman Arus Lebih pada Jaringan Distribusi 20 Kv Gardu Induk Garuda Sakti

    OpenAIRE

    Putra, Ario; Firdaus, Firdaus

    2017-01-01

    PT.PLN: 20 kV network substations Garuda Sakti, frequently interference, one of interferences is the short-circuit current. To install equipment to include Recloser. This paper discuss the analysisof the use Recloser on distribution network 20 kV, this paper also be simulated using the software ETAP 12.6 which will feature some of the parameters for comparison of calculations and data thatalready exists in PLN, with two parameters, short circuit and coordination Recloser with overcurrent rela...

  11. Ca2+-regulatory proteins in cardiomyocytes from the right ventricle in children with congenital heart disease

    Directory of Open Access Journals (Sweden)

    Wu Yihe

    2012-04-01

    Full Text Available Abstract Background Hypoxia and hypertrophy are the most frequent pathophysiological consequence of congenital heart disease (CHD which can induce the alteration of Ca2+-regulatory proteins and inhibit cardiac contractility. Few studies have been performed to examine Ca2+-regulatory proteins in human cardiomyocytes from the hypertrophic right ventricle with or without hypoxia. Methods Right ventricle tissues were collected from children with tetralogy of Fallot [n = 25, hypoxia and hypertrophy group (HH group], pulmonary stenosis [n = 25, hypertrophy group (H group], or small isolated ventricular septal defect [n = 25, control group (C group] during open-heart surgery. Paraffin sections of tissues were stained with 3,3′-dioctadecyloxacarbocyanine perchlorate to measure cardiomyocyte size. Expression levels of Ca2+-regulatory proteins [sarcoplasmic reticulum Ca2+-ATPase (SERCA2a, ryanodine receptor (RyR2, sodiumcalcium exchanger (NCX, sarcolipin (SLN and phospholamban (PLN] were analysed by means of real-time PCR, western blot, or immunofluorescence. Additionally, phosphorylation level of RyR and PLN and activity of protein phosphatase (PP1 were evaluated using western blot. Results Mild cardiomyocyte hypertrophy of the right ventricle in H and HH groups was confirmed by comparing cardiomyocyte size. A significant reduction of SERCA2a in mRNA (P16-phosphorylated PLN was down-regulated (PP Conclusions The decreased SERCA2a mRNA may be a biomarker of the pathological process in the early stage of cyanotic CHD with the hypertrophic right ventricle. A combination of hypoxia and hypertrophy can induce the adverse effect of PLN-Ser16 dephosphorylation. Increased PP1 could result in the decreased PLN-Ser16 and inhibition of PP1 is a potential therapeutic target for heart dysfunction in pediatrics.

  12. Number of evaluated lymph nodes and positive lymph nodes, lymph node ratio, and log odds evaluation in early-stage pancreatic ductal adenocarcinoma: numerology or valid indicators of patient outcome?

    Science.gov (United States)

    Lahat, G; Lubezky, N; Gerstenhaber, F; Nizri, E; Gysi, M; Rozenek, M; Goichman, Y; Nachmany, I; Nakache, R; Wolf, I; Klausner, J M

    2016-09-29

    We evaluated the prognostic significance and universal validity of the total number of evaluated lymph nodes (ELN), number of positive lymph nodes (PLN), lymph node ratio (LNR), and log odds of positive lymph nodes (LODDS) in a relatively large and homogenous cohort of surgically treated pancreatic ductal adenocarcinoma (PDAC) patients. Prospectively accrued data were retrospectively analyzed for 282 PDAC patients who had pancreaticoduodenectomy (PD) at our institution. Long-term survival was analyzed according to the ELN, PLN, LNR, and LODDS. Of these patients, 168 patients (59.5 %) had LN metastasis (N1). Mean ELN and PLN were 13.5 and 1.6, respectively. LN positivity correlated with a greater number of evaluated lymph nodes; positive lymph nodes were identified in 61.4 % of the patients with ELN ≥ 13 compared with 44.9 % of the patients with ELN < 13 (p = 0.014). Median overall survival (OS) and 5-year OS rate were higher in N0 than in N1 patients, 22.4 vs. 18.7 months and 35 vs. 11 %, respectively (p = 0.008). Mean LNR was 0.12; 91 patients (54.1 %) had LNR < 0.3. Among the N1 patients, median OS was comparable in those with LNR ≥ 0.3 vs. LNR < 0.3 (16.7 vs. 14.1 months, p = 0.950). Neither LODDS nor various ELN and PLN cutoff values provided more discriminative information within the group of N1 patients. Our data confirms that lymph node positivity strongly reflects PDAC biology and thus patient outcome. While a higher number of evaluated lymph nodes may provide a more accurate nodal staging, it does not have any prognostic value among N1 patients. Similarly, PLN, LNR, and LODDS had limited prognostic relevance.

  13. How much does care in palliative care wards cost in Poland?

    Science.gov (United States)

    Ciałkowska-Rysz, Aleksandra D; Pokropska, Wieslawa; Łuczak, Jacek; Kaptacz, Anna; Stachowiak, Andrzej; Hurich, Krystyna; Koszela, Monika

    2016-04-01

    The main task of palliative care units is to provide a dignified life for people with advanced progressive chronic disease through appropriate symptom management, communication between medical specialists and the patient and his family, as well as the coordination of care. Many palliative care units struggle with low incomes from the National Health Fund (NHF), which causes serious economic problems. The aim of the study was to estimate of direct and administrative costs of care and the actual cost per patient per day in selected palliative care units and comparison of the results to the valuation of the NHF. The study of the costs of hospitalization of 175 patients was conducted prospectively in five palliative care units (PCUs). The costs directly associated with care were recorded on the specially prepared forms in each unit and also personnel and administrative costs provided by the accounting departments. The total costs of analyzed units amounted to 209 002 EUR (898 712 PLN), while the payment for palliative care services from the NHF amounted to 126 010 EUR (541 844 PLN), which accounted for only 60% of the costs incurred by the units. The average cost per person per day of hospitalization, calculated according to the actual duration of hospitalization in the unit, was 83 EUR (357 PLN), and the average payment from the NHF was 52.8 EUR (227 PLN). Underpayment per person per day was approximately 29.2 EUR (125 PLN). The study showed a significant difference between the actual cost of palliative care units and the level of refund from the NHF. Based on the analysis of costs, the application has been submitted to the NHF to change the reimbursement amount of palliative care services in 2013.

  14. Renovation and uprating of seven hydropower plants in Java

    International Nuclear Information System (INIS)

    Nuessli, W.

    1991-01-01

    The Indonesian Power Authority is planning to renovate and uprate seven hydropower stations in Java to expand plant life expectancy, ensure operating safety and reliability, and increase power and generation within economical limits. The power plants were constructed in the early 1920s and extended between 1945 and 1950. Their capacities vary between 4 and 20 MW. For the renovation project, Colenco Power Consulting Ltd. is acting as a consultant to PLN. In February 1990, Colenco inspected all seven power plants. The results of the inspections served as the basis for the development of renovation plans for each of the seven hydropower plants. To determine the cost of the proposed renovation plans, appraisers had to determine a method for comparing the value of an existing plant to that of a renovated one. The two different evaluation methods used for these comparisons are the focus of this paper

  15. Costs of Stream Maintenance Works in the Poznań District

    Directory of Open Access Journals (Sweden)

    Piotr Stachowski

    2017-12-01

    Full Text Available Water reclamation works, especially those related to stream maintenance, are necessary wherever their lack may cause a risk to the natural environment, as well as human life and property. This paper presents the assessment of the maintenance costs on natural and regulated streams in the years 2010-2016 in the Poznań district. In the analysed years, the costs for works on streams and water-drainage constructions amounted to an average of 1,214,800 PLN per year, which in terms of a 1km stream is approximately 3,575 PLN/km per year. Higher maintenance costs occurred on the regulated streams, where the average cost of a 1 km stream was approximately 7,042 PLN. Moreover, high costs were noted in the works on unregulated streams, where the average cost was approximately 8,948 PLN. The amount of public funding for the maintenance and current operation was quite insufficient, as it covered only 4.2% of the annual average demand. The positive trend is nearly a 6-fold increase in funds for current maintenance compared to the year 2010, when a flood occurred. The results of the conducted analyses indicate the cognitive need and purpose, as well as the economic importance, to establish water reclamation monitoring, as well as develop the existing IT system for recording water reclamation works and water management in agriculture.

  16. Economic efficiency of coal gasification in Poland in reference to the price of CO2 emission rights

    Directory of Open Access Journals (Sweden)

    Kopacz Michał

    2016-01-01

    Full Text Available The article presents the impact of prices of carbon dioxide on the economic efficiency of 14 coal gasification technologies employed for producing electricity, hydrogen and methanol measured with the use of NPV method. All technical, technological and economic assumptions in the assessment have been made for Polish conditions. The impact of CO2 prices were examined in the range of 30-200 PLN/Mg. The production capacity of the base technology corresponds with the fuel consumption of indicative coal having the calorific value of 20.5 GJ/Mg, used in the amount of 100 Mg/h. On the basis of the conducted research, with respect to all technical and economic assumptions, it can be stated that for the base scale there is a clear impact of prices of CO2 emission allowances above the 90 PLN/Mg CO2. Such a level of carbon dioxide prices makes the decision concerning construction of geological sequestration systems (CCS, carbon capture and storage worthwhile. This applies in particular to the production of electric energy. For the variants focused on hydrogen production there is a dominance of variants with CCS system only at the price exceeding 120 PLN/Mg CO2, and in the case of methanol such a situation occurs above 150 PLN/Mg CO2.

  17. A cross-comparison of different techniques for modeling macro-level cyclist crashes.

    Science.gov (United States)

    Guo, Yanyong; Osama, Ahmed; Sayed, Tarek

    2018-04-01

    Despite the recognized benefits of cycling as a sustainable mode of transportation, cyclists are considered vulnerable road users and there are concerns about their safety. Therefore, it is essential to investigate the factors affecting cyclist safety. The goal of this study is to evaluate and compare different approaches of modeling macro-level cyclist safety as well as investigating factors that contribute to cyclist crashes using a comprehensive list of covariates. Data from 134 traffic analysis zones (TAZs) in the City of Vancouver were used to develop macro-level crash models (CM) incorporating variables related to actual traffic exposure, socio-economics, land use, built environment, and bike network. Four types of CMs were developed under a full Bayesian framework: Poisson lognormal model (PLN), random intercepts PLN model (RIPLN), random parameters PLN model (RPPLN), and spatial PLN model (SPLN). The SPLN model had the best goodness of fit, and the results highlighted the significant effects of spatial correlation. The models showed that the cyclist crashes were positively associated with bike and vehicle exposure measures, households, commercial area density, and signal density. On the other hand, negative associations were found between cyclist crashes and some bike network indicators such as average edge length, average zonal slope, and off-street bike links. Copyright © 2018 Elsevier Ltd. All rights reserved.

  18. Intensive training and reduced volume increases muscle FXYD1 expression and phosphorylation at rest and during exercise in athletes

    DEFF Research Database (Denmark)

    Thomassen, Martin; Gunnarsson, Thomas Gunnar Petursson; Christensen, Peter Møller

    2016-01-01

    and phosphorylation were determined by western blotting. Expression of FXYD1 (30%), actin (40%), mTOR (12%), PLN (16%) and CaMKII γ/δ (25%) was higher (P... and during exercise, mainly achieved by an increased FXYD1 ser68 phosphorylation, compared to before the intervention. CaMKII thr287 and eEF2 thr56 phosphorylation at rest and during exercise, overall PKCα/β thr638/641 and mTOR ser2448 phosphorylation during repeated intense exercise as well as resting PLN...

  19. Studi Pemanfaatan Catu Daya Hibrida PLTS 3,7 kWp Dan PLN Pada Instalasi Pengolahan Air Limbah Desa Pemecutan Kaja Denpasar Bali

    Directory of Open Access Journals (Sweden)

    Aries Arimbawa

    2016-11-01

    Full Text Available Abstract—Pemecutan Kaja waste treatment plant (WTP was a community treatment plant located in one of Denpasar city ward to process sewerage produced by community members. The WTP uses radial flow anaerobic system which mainly consists of rabic pro and up flow tanks. The water produced by the WTP was released to nearby river as it already met envinronmental quality standard. The WTP was driven by an electric pump to circulate sewer material within the process flow. The pump was fed by hybrid power supply combining 3.7 kW solar PV and power from utility grid. The WTP was operated by village council of Pemecutan Kaja. The study presented here was result of firstly, evaluation on the utilization and performance of solar PV plant, and secondly, to propose managerial model that can manage the plant effectively and sustainably. The study found that daily average energy produced bythe PVplant was 23.59 kWh yielding cost of energy at IDR 7,766/kWh. Experiment to clean filters of the plant reduced daily energy consumption from 8.84 kWh to 3.05 kWh or 65%. Household that connected to the plant pay monthly subscription currently at IDR 10,000.  However, for sustainable operation of the plant, the household need to pay IDR 51,654. Keywords: Renewable Energy, Solar PV, Hybrid Power Supply, Waste Treatment, Managerial Model Abstrak—Instalasi Pengolahan Air Limbah (IPAL Desa Pemecutan Kaja adalah IPAL yang terletak di salah satu lingkungan kota Denpasar yang berfungi untuk mengolah air limbah yang dihasilkan oleh anggota masyarakat. IPAL ini meggunakan sistem radial flow anaerobic yang terdiri tangki rabic pro dan tangki up flow filter. Air hasil pengolahan limbah dapat langsung disalurkan ke sungai karena sudah memenuhi baku mutu limbah cair. IPAL ini menggunakan pompa listrik untuk mengalirkan limbah menuju tangki penyaringan. Pompa ini mengunakan catu daya hibrida PLTS 3,7 kW dan PLN. IPAL ini dikelola langsung oleh masyarakat desa Pemecutan Kaja. Hasil

  20. 8000 yr of vegetation reconstruction from the Great Basin (Nevada, USA): the contribution of Non-Pollen Palynomorphs.

    Science.gov (United States)

    Tunno, I.; Mensing, S. A.

    2017-12-01

    Multiproxy records from the Great Basin showed that a severe drought occurred in the area between 3000-1850 BP (Mensing et al., 2013). The pollen analysis on a 7m sediment core from Stonehouse Meadow revealed that during this period arboreal pollen dropped abruptly, reaching the lowest percentage ( 10%) around 2500 BP. At the same time, grass and herbs increased significantly ( 60%) together with the total carbonate percentage (TC%). To better understand this dramatic event, the analysis of Non-Pollen Palynomorphs (NPPs) was conducted. NPPs are microfossils that survive the chemical treatment during pollen extraction and appear in pollen slides. They are valuable indicators of climate- and human-induced changes, and due to their different origin, NPPs can be integrated with pollen analysis to corroborate and improve the information provided by pollen records. To obtain more reliable information, fossil NPPs from the sediment core were compared to modern NPPs and the pollen records. Modern samples, represented by mineral soil and sediment specimens, were collected around the meadow in 2015. Fossil NPPs were counted from the same sediment core subsamples previously analyzed for pollen records. A total of 64 different NPPs were identified from both modern and fossil samples, 33 of which were identified as unknowns and given an identification code. While several of the known NPPs were consistent with the data provided by pollen record, the most crucial information was provided by some of the unknown NPPs, such as PLN-01, PLN-20 and PLN-11. The presence of PLN-01 and PLN-20 on the edge of the meadow in the modern samples and right before and after the driest period in the core, supports the evidence of a drought, when the meadow was likely shrinking during the transition from a wetter to a drier period and expanding once again after the drought. PLN-11 appears to be related to the drought as well, occurring exclusively during the driest period. However, this NPP was not

  1. Viral Reservoirs in Lymph Nodes of FIV-Infected Progressor and Long-Term Non-Progressor Cats during the Asymptomatic Phase.

    Directory of Open Access Journals (Sweden)

    C D Eckstrand

    Full Text Available Examination of a cohort of cats experimentally infected with feline immunodeficiency virus (FIV for 5.75 years revealed detectable proviral DNA in peripheral blood mononuclear cells (PBMCs harvested during the asymptomatic phase, undetectable plasma viral RNA (FIV gag, and rarely detectable cell-associated viral RNA. Despite apparent viral latency in peripheral CD4+ T cells, circulating CD4+ T cell numbers progressively declined in progressor animals. The aim of this study was to explore this dichotomy of peripheral blood viral latency in the face of progressive immunopathology. The viral replication status, cellular immunophenotypes, and histopathologic features were compared between popliteal lymph nodes (PLNs and peripheral blood. Also, we identified and further characterized one of the FIV-infected cats identified as a long-term non-progressor (LTNP.PLN-derived leukocytes from FIV-infected cats during the chronic asymptomatic phase demonstrated active viral gag transcription and FIV protein translation as determined by real-time RT-PCR, Western blot and in situ immunohistochemistry, whereas viral RNA in blood leukocytes was either undetectable or intermittently detectable and viral protein was not detected. Active transcription of viral RNA was detectable in PLN-derived CD4+ and CD21+ leukocytes. Replication competent provirus was reactivated ex vivo from PLN-derived leukocytes from three of four FIV-infected cats. Progressor cats showed a persistent and dramatically decreased proportion and absolute count of CD4+ T cells in blood, and a decreased proportion of CD4+ T cells in PLNs. A single long-term non-progressor (LTNP cat persistently demonstrated an absolute peripheral blood CD4+ T cell count indistinguishable from uninfected animals, a lower proviral load in unfractionated blood and PLN leukocytes, and very low amounts of viral RNA in the PLN.Collectively our data indicates that PLNs harbor important reservoirs of ongoing viral

  2. Serial changes on MR imaging of herniated lumber discs treated by percutaneous laser nucleotomy. Correlation with early clinical results

    International Nuclear Information System (INIS)

    Hiraishi, Kumiko; Ohmori, Naoki; Kosaka, Riya; Yonezawa, Takumi; Onomura, Toshinobu; Adachi, Itaru; Matsuoka, Takae; Honghan, Gong; Narabayashi, Isamu

    1996-01-01

    Percutaneous Laser Nucleotomy (PLN) is a new treatment for disc herniation applying neodymium: yttrium-aluminum-garnet (Nd : YAG) laser through inserted needle into the center of the disc, with less invasion and shorter hospitalization than conventional open surgery. Serial MR images were observed in 21 patients before and after PLN. Canal occupying ratio (COR) and signal intensity (S.I.) of herniated disc were measured. Recovery rate of symptoms was 57.2%, based on scoring system proposed by the Japanese Orthopaedic Association for low-back pain (JOA score). The successful group (≥30% improvement in JOA score) showed rapid decrease in signal intensity, though the ineffective group ( 2 -weighted sequence. Increase of signal intensity was observed in some patients whose symptoms had become worse. This may correlate with increase of water content and inner pressure on the disc. There was no significant difference between pre- and post-COR; however, more than 10% COR decrease was observed in 7 patients and symptoms improved in these cases. Thus the prognosis of the patients treated with PLN can be assessed by MR findings. (author)

  3. Features of the popliteal lymph nodes seen on musculoskeletal MRI in a Western population

    Energy Technology Data Exchange (ETDEWEB)

    Musters, Gijsbert Daniel [University of Amsterdam, Master of Science at Academic Medical Center, Amsterdam (Netherlands); University of Amsterdam, Department of Radiology, Academic Medical Center, Amsterdam (Netherlands); Kleipool, Roeland P. [University of Amsterdam, Department of Anatomy, Embryology, and Physiology, Academic Medical Center, Amsterdam (Netherlands); Bipat, Shandra; Maas, Mario [University of Amsterdam, Department of Radiology, Academic Medical Center, Amsterdam (Netherlands)

    2011-08-15

    To asses the features and explore the clinical relevance of popliteal lymph nodes (PLNs) detected on MRI examination for different pathologies of the knee. A total of 150 knee MRIs, which were conducted for various indications, were retrospectively collected from the Picture Archiving and Communication System. Imaging planes in at least two orthogonal planes were mandatory, with a field of view extending 15 cm cranial from the joint space. The localization of the PLN was determined by measuring the distance of the lowest border of the PLN to the lowest border of the lateral femoral condyle. Clinical diagnosis was obtained from radiology reports and a statistician performed the statistical analysis. The patients were 70 males [mean age 36.6 years (range: 5-72 years)] and 80 females [mean age 41.1 years (range: 9-76 years)]. In 36.7% of the patients, a PLN was visible. The number of PLNs was negatively associated with age (p < 0.001). The mean number of PLNs was 0.5 PLN per patient. The mean length, height, and width were respectively: 0.57 cm (SD = 0.15), 0.84 cm (SD = 0.26), and 0.71 cm (SD = 0.23). The mean location was 5.8 cm (SD = 1.61). No association was found between the presence of PLNs and internal derangement, inflammation, or cancer (p = 0.368). PLNs appearance is age related, with a higher frequency at a young age. The presence of the PLNs showed no relation to a specific clinical situation. (orig.)

  4. Crew Transportation Technical Management Processes

    Science.gov (United States)

    Mckinnie, John M. (Compiler); Lueders, Kathryn L. (Compiler)

    2013-01-01

    Under the guidance of processes provided by Crew Transportation Plan (CCT-PLN-1100), this document, with its sister documents, International Space Station (ISS) Crew Transportation and Services Requirements Document (CCT-REQ-1130), Crew Transportation Technical Standards and Design Evaluation Criteria (CCT-STD-1140), Crew Transportation Operations Standards (CCT STD-1150), and ISS to Commercial Orbital Transportation Services Interface Requirements Document (SSP 50808), provides the basis for a National Aeronautics and Space Administration (NASA) certification for services to the ISS for the Commercial Provider. When NASA Crew Transportation System (CTS) certification is achieved for ISS transportation, the Commercial Provider will be eligible to provide services to and from the ISS during the services phase.

  5. Personality as a moderator of context effects on academic achievement

    NARCIS (Netherlands)

    Hendriks, A.A.J.; Kuyper, H.; Lubbers, M.J; Van der Werf, M.P.C.

    We investigated whether personality moderates group influence of classmates on academic achievement and whether these so-called context effects can be attributed to peer pressure. The sample consisted of 2498 students in their first year of Dutch secondary education. The data were analyzed by a

  6. Pečující otcové: Příběhy plné odlišnosti

    Czech Academy of Sciences Publication Activity Database

    Maříková, Hana

    2009-01-01

    Roč. 45, č. 1 (2009), s. 89-113 ISSN 0038-0288 R&D Projects: GA ČR(CZ) GA403/09/1839; GA AV ČR 1QS700280503 Institutional research plan: CEZ:AV0Z70280505 Keywords : gender difference * gender similarity * gender in/equality Subject RIV: AO - Sociology, Demography Impact factor: 0.562, year: 2009

  7. The membrane attack complex of complement contributes to plasmin-induced synthesis of platelet-activating factor by endothelial cells and neutrophils.

    Science.gov (United States)

    Lupia, Enrico; Del Sorbo, Lorenzo; Bergerone, Serena; Emanuelli, Giorgio; Camussi, Giovanni; Montrucchio, Giuseppe

    2003-08-01

    Thrombolytic agents, used to restore blood flow to ischaemic tissues, activate several enzymatic systems with pro-inflammatory effects, thus potentially contributing to the pathogenesis of ischaemia-reperfusion injury. Platelet-activating factor (PAF), a phospholipid mediator of inflammation, has been implicated in the pathogenesis of this process. We previously showed that the infusion of streptokinase (SK) induces the intravascular release of PAF in patients with acute myocardial infarction (AMI), and that cultured human endothelial cells (EC) synthesized PAF in response to SK and plasmin (PLN). In the present study, we investigated the role of the membrane attack complex (MAC) of complement in the PLN-induced synthesis of PAF. In vivo, we showed a correlation between the levels of soluble terminal complement components (sC5b-9) and the concentrations of PAF detected in blood of patients with AMI infused with SK. In vitro both EC and polymorphonuclear neutrophils (PMN), incubated in the presence of PLN and normal human serum, showed an intense staining for the MAC neoepitope, while no staining was detected when they were incubated with PLN in the presence of heat-inactivated normal human serum. Moreover, the insertion of MAC on EC and PMN plasmamembrane elicited the synthesis of PAF. In conclusion, our results elucidate the mechanisms involved in PAF production during the activation of the fibrinolytic system, showing a role for complement products in this setting. The release of PAF may increase the inflammatory response, thus limiting the beneficial effects of thrombolytic therapy. Moreover, it may have a pathogenic role in other pathological conditions, such as transplant rejection, tumoral angiogenesis, and septic shock, where fibrinolysis is activated.

  8. High resolution systematic digital histological quantification of cardiac fibrosis and adipose tissue in phospholamban p.Arg14del mutation associated cardiomyopathy.

    Directory of Open Access Journals (Sweden)

    Johannes M I H Gho

    Full Text Available Myocardial fibrosis can lead to heart failure and act as a substrate for cardiac arrhythmias. In dilated cardiomyopathy diffuse interstitial reactive fibrosis can be observed, whereas arrhythmogenic cardiomyopathy is characterized by fibrofatty replacement in predominantly the right ventricle. The p.Arg14del mutation in the phospholamban (PLN gene has been associated with dilated cardiomyopathy and recently also with arrhythmogenic cardiomyopathy. Aim of the present study is to determine the exact pattern of fibrosis and fatty replacement in PLN p.Arg14del mutation positive patients, with a novel method for high resolution systematic digital histological quantification of fibrosis and fatty tissue in cardiac tissue. Transversal mid-ventricular slices (n = 8 from whole hearts were collected from patients with the PLN p.Arg14del mutation (age 48±16 years; 4 (50% male. An in-house developed open source MATLAB script was used for digital analysis of Masson's trichrome stained slides (http://sourceforge.net/projects/fibroquant/. Slides were divided into trabecular, inner and outer compact myocardium. Per region the percentage of connective tissue, cardiomyocytes and fatty tissue was quantified. In PLN p.Arg14del mutation associated cardiomyopathy, myocardial fibrosis is predominantly present in the left posterolateral wall and to a lesser extent in the right ventricular wall, whereas fatty changes are more pronounced in the right ventricular wall. No difference in distribution pattern of fibrosis and adipocytes was observed between patients with a clinical predominantly dilated and arrhythmogenic cardiomyopathy phenotype. In the future, this novel method for quantifying fibrosis and fatty tissue can be used to assess cardiac fibrosis and fatty tissue in animal models and a broad range of human cardiomyopathies.

  9. Burden of suicide in Poland in 2012: how could it be measured and how big is it?

    Science.gov (United States)

    Orlewska, Katarzyna; Orlewska, Ewa

    2018-04-01

    The aim of our study was to estimate the health-related and economic burden of suicide in Poland in 2012 and to demonstrate the effects of using different assumptions on the disease burden estimation. Years of life lost (YLL) were calculated by multiplying the number of deaths by the remaining life expectancy. Local expected YLL (LEYLL) and standard expected YLL (SEYLL) were computed using Polish life expectancy tables and WHO standards, respectively. In the base case analysis LEYLL and SEYLL were computed with 3.5 and 0% discount rates, respectively, and no age-weighting. Premature mortality costs were calculated using a human capital approach, with discounting at 5%, and are reported in Polish zloty (PLN) (1 euro = 4.3 PLN). The impact of applying different assumptions on base-case estimates was tested in sensitivity analyses. The total LEYLLs and SEYLLs due to suicide were 109,338 and 279,425, respectively, with 88% attributable to male deaths. The cost of male premature mortality (2,808,854,532 PLN) was substantially higher than for females (177,852,804 PLN). Discounting and age-weighting have a large effect on the base case estimates of LEYLLs. The greatest impact on the estimates of suicide-related premature mortality costs was due to the value of the discount rate. Our findings provide quantitative evidence on the burden of suicide. In our opinion each of the demonstrated methods brings something valuable to the evaluation of the impact of suicide on a given population, but LEYLLs and premature mortality costs estimated according to national guidelines have the potential to be useful for local public health policymakers.

  10. Internet plan and planning

    Directory of Open Access Journals (Sweden)

    Kahriman Emina

    2008-01-01

    Full Text Available Paper discuss specific features of internet plan as well as planning as management process in general in the contemporary environment. No need to stress out that marketing plan and marketing planning is core activity in approaching to market. At the same time, there are a lot specific c request in preparing marketing plan comparing to business planning due to marketing plan is an essential part. The importance of internet plan and planning rely on specific features of the internet network but as a part of general corporate as well as marketing strategy.

  11. Effects of the Peptide Pheromone Plantaricin A and Cocultivation with Lactobacillus sanfranciscensis DPPMA174 on the Exoproteome and the Adhesion Capacity of Lactobacillus plantarum DC400

    Science.gov (United States)

    Calasso, Maria; Di Cagno, Raffaella; Campanella, Daniela; Minervini, Fabio; Gobbetti, Marco

    2013-01-01

    This study aimed at investigating the extracellular and cell wall-associated proteins (exoproteome) of Lactobacillus plantarum DC400 when cultivated on modified chemically defined medium (CDM) supplemented with the chemically synthesized pheromone plantaricin A (PlnA) or cocultured with L. plantarum DPPMA20 or Lactobacillus sanfranciscensis DPPMA174. Compared to monoculture, two-dimensional gel electrophoresis (2-DE) analysis showed that the exoproteome of L. plantarum DC400 was affected by PlnA and cocultivation with strains DPPMA20 and, especially, DPPMA174. The highest similarity of the 2-DE maps was found between DC400 cells cultivated in monoculture and in coculture with strain DPPMA20. Almost all extracellular proteins (22 spots) and cell wall-associated proteins (40 spots) which showed decreased or increased levels of synthesis during growth in CDM supplemented with PlnA and/or in coculture with strain DPPMA20 or DPPMA174 were identified. On the basis of the sequences in the Kyoto Encyclopedia of Genes and Genomes database, changes to the exoproteome concerned proteins involved in quorum sensing (QS), the transport system, stress response, carbohydrate metabolism and glycolysis, oxidation/reduction processes, the proteolytic system, amino acid metabolism, cell wall and catabolic processes, and cell shape, growth, and division. Cultivation with PlnA and cocultivation with strains DPPMA20 and, especially, DPMMA174 markedly increased the capacity of L. plantarum DC400 to form biofilms, to adhere to human Caco-2 cells, and to prevent the adhesion of potential intestinal pathogens. These phenotypic traits were in part related to oversynthesized moonlighting proteins (e.g., DnaK and GroEL, pyruvate kinase, enolase, and glyceraldehyde-3-phosphate dehydrogenase) in response to QS mechanisms and interaction with L. plantarum DPPMA20 and, especially, L. sanfranciscensis DPPMA174. PMID:23396346

  12. Probabilistic logic networks a comprehensive framework for uncertain inference

    CERN Document Server

    Goertzel, Ben; Goertzel, Izabela Freire; Heljakka, Ari

    2008-01-01

    This comprehensive book describes Probabilistic Logic Networks (PLN), a novel conceptual, mathematical and computational approach to uncertain inference. A broad scope of reasoning types are considered.

  13. Magnetic field effects in UNi.sub.1/3./sub.Ru.sub.2/3./sub.Al

    Czech Academy of Sciences Publication Activity Database

    Alsmadi, A. M.; El-Khatib, S.; de Chatel, P.F.; Nakotte, H.; Lacerda, A. H.; Jung, M. H.; Andreev, Alexander V.; Honda, F.; Sechovský, V.

    2005-01-01

    Roč. 97, - (2005), 10A919/1-10A919/3 ISSN 0021-8979 R&D Projects: GA ČR(CZ) GA202/02/0739 Keywords : UNi 1/3 Ru 2/3 Al * magnetic field effects Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 2.498, year: 2005

  14. 76 FR 19356 - Video Programming and Accessibility Advisory Committee; Announcement of Date of Next Meeting

    Science.gov (United States)

    2011-04-07

    ... you will need and tell us how to contact you if we need more information. Make your request as early...-418-2498 (voice), 202-418-1169 (TTY), or [email protected] (e-mail); or Alison Neplokh, Media Bureau... or digital broadcast television; accessible user interfaces on video programming devices; and...

  15. Looking for answers to L-type calcium channels in the ageing brain (Commentary on Zanos et al.)

    Czech Academy of Sciences Publication Activity Database

    Proft, Juliane; Weiss, Norbert

    2015-01-01

    Roč. 42, č. 8 (2015), s. 2496-2498 ISSN 0953-816X R&D Projects: GA ČR GA15-13556S; GA MŠk 7AMB15FR015 Institutional support: RVO:61388963 Keywords : rat basal forebrain * age * neurons Subject RIV: CE - Biochemistry Impact factor: 2.975, year: 2015

  16. Computed tomography, magnetic resonance imaging and FDG positron emission tomography in the management of vulvar malignancies

    International Nuclear Information System (INIS)

    Lin, Gigin; Chen, Chao-Yu; Liu, Feng-Yuan; Yang, Lan-Yan; Huang, Huei-Jean; Chou, Hung-Hsueh; Lai, Chyong-Huey; Huang, Yi-Ting; Jung, Shih-Ming; Ng, Koon-Kwan

    2015-01-01

    To prospectively evaluate the value of CT or MRI (CT/MRI) and PET in the management of vulvar malignancies. Abdominal and pelvic CT/MRI and whole-body 18 F-FDG (fluorodeoxyglucose) PET or PET/CT (collectively designated PET hereafter) were performed. Lesion status was determined by the pathological findings or clinical follow-up. The diagnostic efficacy was evaluated by receiver operating characteristic (ROC) curve analysis. The clinical impact of PET was determined on a per scan basis. Twenty-three patients were enrolled, and 38 PET examinations were performed. CT/MRI and PET studies were used for primary staging (n = 17), monitoring the response (n = 7) and restaging after recurrence (n = 14). In primary staging, there was no significant difference between CT/MRI and PET in detecting metastatic inguinal lymph nodes (ILN). CT/MRI was significantly more efficacious than PET in detecting pelvic lymph node (PLN) or distant metastasis (p = 0.007 by ROC per patient basis). PET findings resulted in two positive impacts and one negative impact for both primary staging and restaging. False-positive PLN or distant metastasis PET findings are not uncommon, and hence should be interpreted with caution. PET can be supportive when metastatic ILN/PLN or distant metastasis is suspected on CT/MRI. (orig.)

  17. Perlecan domain 1 recombinant proteoglycan augments BMP-2 activity and osteogenesis

    Directory of Open Access Journals (Sweden)

    DeCarlo Arthur A

    2012-09-01

    Full Text Available Abstract Background Many growth factors, such as bone morphogenetic protein (BMP-2, have been shown to interact with polymers of sulfated disacharrides known as heparan sulfate (HS glycosaminoglycans (GAGs, which are found on matrix and cell-surface proteoglycans throughout the body. HS GAGs, and some more highly sulfated forms of chondroitin sulfate (CS, regulate cell function by serving as co-factors, or co-receptors, in GF interactions with their receptors, and HS or CS GAGs have been shown to be necessary for inducing signaling and GF activity, even in the osteogenic lineage. Unlike recombinant proteins, however, HS and CS GAGs are quite heterogenous due, in large part, to post-translational addition, then removal, of sulfate groups to various positions along the GAG polymer. We have, therefore, investigated whether it would be feasible to deliver a DNA pro-drug to generate a soluble HS/CS proteoglycan in situ that would augment the activity of growth-factors, including BMP-2, in vivo. Results Utilizing a purified recombinant human perlecan domain 1 (rhPln.D1 expressed from HEK 293 cells with HS and CS GAGs, tight binding and dose-enhancement of rhBMP-2 activity was demonstrated in vitro. In vitro, the expressed rhPln.D1 was characterized by modification with sulfated HS and CS GAGs. Dose-enhancement of rhBMP-2 by a pln.D1 expression plasmid delivered together as a lyophilized single-phase on a particulate tricalcium phosphate scaffold for 6 or more weeks generated up to 9 fold more bone volume de novo on the maxillary ridge in a rat model than in control sites without the pln.D1 plasmid. Using a significantly lower BMP-2 dose, this combination provided more than 5 times as much maxillary ridge augmentation and greater density than rhBMP-2 delivered on a collagen sponge (InFuse™. Conclusions A recombinant HS/CS PG interacted strongly and functionally with BMP-2 in binding and cell-based assays, and, in vivo, the pln.247 expression plasmid

  18. DEVELOPMENT AND DEPLOYMENT OF THE MOBILE ARM RETRIEVAL SYSTEM (MARS) - 12187

    Energy Technology Data Exchange (ETDEWEB)

    BURKE CA; LANDON MR; HANSON CE

    2011-11-08

    Washington River Protection Solutions (WRPS) is developing and deploying Mobile Arm Retrieval System (MARS) technologies solutions to support retrieval of radioactive and chemical waste from underground single shell storage tanks (SST) located at the Hanford Site, which is near Richland, Washington. WRPS has developed the MARS using a standardized platform that is capable of deploying multiple retrieval technologies. To date, WRPS, working with their mentor-protege company, Columbia Energy and Environmental Services (CEES), has developed two retrieval mechanisms, MARS-Sluicing (MARS-S) and MARS-Vacuum (MARS-V). MARS-S uses pressurized fluids routed through spray nozzles to mobilize waste materials to a centrally located slurry pump (deployed in 2011). MARS-V uses pressurized fluids routed through an eductor nozzle. The eductor nozzle allows a vacuum to be drawn on the waste materials. The vacuum allows the waste materials to be moved to an in-tank vessel, then extracted from the SST and subsequently pumped to newer and safer double shell tanks (DST) for storage until the waste is treated for disposal. The MARS-S system is targeted for sound SSTs (i.e., non leaking tanks). The MARS-V is targeted for assumed leaking tanks or those tanks that are of questionable integrity. Both versions of MARS are beinglhave been developed in compliance with WRPS's TFC-PLN-90, Technology Development Management Plan [1]. TFC-PLN-90 includes a phased approach to design, testing, and ultimate deployment of new technologies. The MARS-V is scheduled to be deployed in tank 241-C-105 in late 2012.

  19. Research and development efforts in the implementation of nuclear power programme in Indonesia

    International Nuclear Information System (INIS)

    Suhaemi, T.

    1986-04-01

    Research and development efforts in the implementation of nuclear power programme in Indonesia are presented. According to Indonesia Law, the National Atomic Energy Agency (BATAN) is an official body which is reponsible for all aspects of nuclear development. In implementing the nuclear power, BATAN together with the State Electricity Corporation (PLN) have pioneered the introduction of nuclear power plant in Indonesia by carrying out various activities, studies, seminars, workshops and report writings. A nuclear power planning study was carried out jointly with the International Atomic Energy Agency. The feasibility studies were also carried out by NIRA, an Italian consultant firm in cooperation with BATAN and PLN. To improve research and development, BATAN has established 5 research nuclear centres which function as centres of basic and applied research, isotope and radiation application, standardization and calibration and uranium exploration. Nowadays BATAN is constructing a sophisticated and multidisciplinary complex at Serpong near Jakarta. It is hoped that the participation of the national industry can be synchronized to the construction of the first nuclear power in Indonesia. To endorse the movement towards the industrial and technological future, the National Centre for Research, Science and Technology (known as PUSPITEK) has been established. There will be 12 different laboratories providing facilities for research and development of all aspects of technology. For training manpower, BATAN has established the Education and Training Centre (PUSDIKLAT). BATAN has also collaborated with universities, such as Gadjahmada University in Yogyakarta, in establishing Nuclear Engineering Division in the School of Engineering. 6 refs, 3 figs

  20. Indonesia lays out a power privatisation agenda

    Energy Technology Data Exchange (ETDEWEB)

    1991-07-15

    Indonesia is preparing to embark on a major power sector privatisation programme in order to stimulate the installation of new electricity capacity, which at present stands at little more than 9,000 MW. This figure, however, represents a 100% increase in capacity in the last five years, up from 4,600 MW in 1984-85. Much of the new capacity is coal-based and the state utility, PLN, new operates 1,730 MW of coal-fired capacity. Backed by East Kalimantan and Sumatran coal deposits, Indonesia plans to further increase domestic coal use for electric power generation over the next 10 years. The PLN will add three 600MW units at Suralaya, four 400MW units at Paiton in East Java, two 65MW mine-mouth units at Bukit Asam, Sumatra and two 65MW mine-mouth units at Ombilin, Sumatra. Private generators will be given the opportunity to participate in coal-based electricity supply under build-own-operate schemes through the installation of four 600 MW units at Paiston, five 600 MW units at Tanjing Jati, Central Java, two 600 MW units in west Java, two 65 MW units at Taraham, Sumatra and four 45 MW units at Banjarmasin, Kalimantan. A substantial amount of private capacity is in fact already under development, particularly in Sumatra and Batam island. Some private companies have identified projects that will be required to supply power to industrial estates; some projects may consist of several units totalling 1,000 MW or more at a single site.

  1. DEVELOPMENT AND DEPLOYMENT OF THE MOBILE ARM RETRIEVAL SYSTEM (MARS) - 12187

    Energy Technology Data Exchange (ETDEWEB)

    BURKE CA; LANDON MR; HANSON CE

    2012-01-30

    Washington River Protection Solutions (WRPS) is developing and deploying Mobile Arm Retrieval System (MARS) technologies solutions to support retrieval of radioactive and chemical waste from underground single shell storage tanks (SST) located at the Hanford Site, which is near Richland, Washington. WRPS has developed the MARS using a standardized platform that is capable of deploying multiple retrieval technologies. To date, WRPS, working with their mentor-protege company, Columbia Energy and Environmental Services (CEES), has developed two retrieval mechanisms, MARS-Sluicing (MARS-S) and MARS-Vacuum (MARS-V). MARS-S uses pressurized fluids routed through spray nozzles to mobilize waste materials to a centrally located slurry pump (deployed in 2011). MARS-V uses pressurized fluids routed through an eductor nozzle. The eductor nozzle allows a vacuum to be drawn on the waste materials. The vacuum allows the waste materials to be moved to an in-tank vessel, then extracted from the SST and subsequently pumped to newer and safer double shell tanks (DST) for storage until the waste is treated for disposal. The MARS-S system is targeted for sound SSTs (i.e., non leaking tanks). The MARS-V is targeted for assumed leaking tanks or those tanks that are of questionable integrity. Both versions of MARS are being/have been developed in compliance with WRPS's TFC-PLN-90, Technology Development Management Plan. TFC-PLN-90 includes a phased approach to design, testing, and ultimate deployment of new technologies. The MARS-V is scheduled to be deployed in tank 241-C-105 in late 2012.

  2. Personality as a Moderator of Context Effects on Academic Achievement

    Science.gov (United States)

    Hendriks, A. A. Jolijn; Kuyper, Hans; Lubbers, Miranda J.; Van der Werf, Margaretha P. C.

    2011-01-01

    We investigated whether personality moderates group influence of classmates on academic achievement and whether these so-called context effects can be attributed to peer pressure. The sample consisted of 2498 students in their first year of Dutch secondary education. The data were analyzed by a two-level (students within classes) analysis,…

  3. PENGARUH ANTAR PERSPEKTIF NON KEUANGAN SERTA IMPLIKASINYA TERHADAP PERSPEKTIF KEUANGAN BERDASARKAN BALANCED SCORECARD

    Directory of Open Access Journals (Sweden)

    Alfira Sofia

    2015-08-01

    In this research note that there is significant influence between non financial perspective at PT PLN (Persero and there is significant influence from non-financial perspective to financial perspective.

  4. Autologous bone marrow mononuclear cell delivery to dilated ...

    African Journals Online (AJOL)

    Autologous bone marrow mononuclear cell delivery to dilated cardiomyopathy patients: A clinical trial. PLN Kaparthi, G Namita, LK Chelluri, VSP Rao, PK Shah, A Vasantha, SK Ratnakar, K Ravindhranath ...

  5. The costs of heart failure in Poland from the public payer's perspective. Polish programme assessing diagnostic procedures, treatment and costs in patients with heart failure in randomly selected outpatient clinics and hospitals at different levels of care: POLKARD.

    Science.gov (United States)

    Czech, Marcin; Opolski, Grzegorz; Zdrojewski, Tomasz; Dubiel, Jacek S; Wizner, Barbara; Bolisęga, Dorota; Fedyk-Łukasik, Małgorzata; Grodzicki, Tomasz

    2013-01-01

    Heart failure (HF) is a chronic disease of great clinical and economic significance for both the healthcare system and patients themselves. To determine the consumption of medical resources for treatment and care of HF patients and to estimate the related costs. The study involved 400 primary care practices and 396 specialist outpatient clinics, as well as 259 hospitals at all reference levels. The sample was representative and supplemented with patient interview data. Based on the consumption of particular resources and the unit costs of services in 2011, costs of care for HF patients in Poland were estimated. Separate analyses were conducted depending on the stage of the disease (according to NYHA classification I-IV). The public payer's perspective and a one year time horizon were adopted. Direct annual costs of an HF patient's treatment in Poland may range between PLN 3,373.23 and 7,739.49 (2011), the main cost item being hospitalisation. The total costs for the healthcare system could be as high as PLN 1,703 million, which is 3.16% of the National Health Fund's budget (Ex. rate from 05.03.2012: 1 EUR = 4.14 PLN). The costs of treating heart failure in Poland are high; proper allocation of resources to diagnostic procedures and treatment may contribute to rationalisation of the relevant expenditure.

  6. Bayesian Poisson hierarchical models for crash data analysis: Investigating the impact of model choice on site-specific predictions.

    Science.gov (United States)

    Khazraee, S Hadi; Johnson, Valen; Lord, Dominique

    2018-08-01

    The Poisson-gamma (PG) and Poisson-lognormal (PLN) regression models are among the most popular means for motor vehicle crash data analysis. Both models belong to the Poisson-hierarchical family of models. While numerous studies have compared the overall performance of alternative Bayesian Poisson-hierarchical models, little research has addressed the impact of model choice on the expected crash frequency prediction at individual sites. This paper sought to examine whether there are any trends among candidate models predictions e.g., that an alternative model's prediction for sites with certain conditions tends to be higher (or lower) than that from another model. In addition to the PG and PLN models, this research formulated a new member of the Poisson-hierarchical family of models: the Poisson-inverse gamma (PIGam). Three field datasets (from Texas, Michigan and Indiana) covering a wide range of over-dispersion characteristics were selected for analysis. This study demonstrated that the model choice can be critical when the calibrated models are used for prediction at new sites, especially when the data are highly over-dispersed. For all three datasets, the PIGam model would predict higher expected crash frequencies than would the PLN and PG models, in order, indicating a clear link between the models predictions and the shape of their mixing distributions (i.e., gamma, lognormal, and inverse gamma, respectively). The thicker tail of the PIGam and PLN models (in order) may provide an advantage when the data are highly over-dispersed. The analysis results also illustrated a major deficiency of the Deviance Information Criterion (DIC) in comparing the goodness-of-fit of hierarchical models; models with drastically different set of coefficients (and thus predictions for new sites) may yield similar DIC values, because the DIC only accounts for the parameters in the lowest (observation) level of the hierarchy and ignores the higher levels (regression coefficients

  7. The foundations and the benefactors of Nowodworski Schools in Krakow

    Directory of Open Access Journals (Sweden)

    Tomasz Graff

    2013-12-01

    Full Text Available Nowodworski Schools, whose current institutionalized continuator is Bartłomiej Nowodworski High School, have a legacy of a long history. The idea to found private schools was initially brought forward by the authorities and professors of the Cracovian University in 1586. The project was finally launched in 1588 mainly due to energetic steps taken by the subsequent chancellor of the Cracovian University doctor of medicine – Stanisław Pik Zawadzki. Over the first decades of its existence the schools faced numerous hardship. The institution was underfunded and both professors and students were exposed to epidemics so frequent in those times, such as for instance the plague in September 1588. Some conservative professors of the University also called for closing the academic colonies. Despite all the predicaments, the institution managed to survive. The most important benefactor for private schools in those difficult years was a Cracovian bishop Piotr Tylicki (in office: 1607–1616, who with the consent of the local chapter, donated PLN 10 000 to fund a separate professor department where the professors were obliged to give a one hour daily lecture in The Upper College as well as 2 hour classes in pronunciation and stylistic in private schools. The situation, however, did not improved significantly. In those times of crisis of private schooling there appeared the foundations of the Knight of the Maltese Order – Barłomiej Nowodworski. Nowodworski was a benefactor for numerous institutions, however, his most famous charity was his foundations for Nowodworski Schools. He donated PLN 8000 in 1612, 1617 and PLN 7000 in 1619 making it possible for those private schools to survive the difficult times. Nowodworski Schools had many benefactors, however, besides the foundation of B. Nowodworski the most prominent benefactors were Gabriel Prewancjusz Władysławski. He donated PLN 50 000. Thanks to his efforts and with the contribution from the King

  8. Planning documents: a business planning strategy.

    Science.gov (United States)

    Kaehrle, P A

    2000-06-01

    Strategic planning and business plan development are essential nursing management skills in today's competitive, fast paced, continually changing health care environment. Even in times of great uncertainty, nurse managers need to plan and forecast for the future. A well-written business plan allows nurse managers to communicate their expertise and proactively contribute to the programmatic decisions and changes occurring within their patient population or service area. This article presents the use of planning documents as a practical, strategic business planning strategy. Although the model addresses orthopedic services specifically, nurse managers can gain an understanding and working knowledge of planning concepts that can be applied to all patient populations.

  9. Non-parametric Bayesian models of response function in dynamic image sequences

    Czech Academy of Sciences Publication Activity Database

    Tichý, Ondřej; Šmídl, Václav

    2016-01-01

    Roč. 151, č. 1 (2016), s. 90-100 ISSN 1077-3142 R&D Projects: GA ČR GA13-29225S Institutional support: RVO:67985556 Keywords : Response function * Blind source separation * Dynamic medical imaging * Probabilistic models * Bayesian methods Subject RIV: BB - Applied Statistics, Operational Research Impact factor: 2.498, year: 2016 http://library.utia.cas.cz/separaty/2016/AS/tichy-0456983.pdf

  10. Prime Contract Awards by Service Category and Federal Supply Classification, Fiscal Years 1982, 1983, 1984, 1985.

    Science.gov (United States)

    1985-01-01

    GAMES TOYS AND WHEELED GOODS 711 351 568 380 7830 RECREATIONAL AND GYMNASTIC EQUIPMENT 3,938 2,498 5.248 3,790 TOTAL 8,292 5.278 7,703 6.107 79 CLEANING...PAINTS DOPES VARNISHES AND RELATED PROD 10,453 3.478 3.662 5,123 8020 PAINT AND ARTISTS BRUSHES 11 0 0 0 8030 PRESERVATIVE AND SEALING COMPOUNDS 2.169

  11. Preparative isoelectric focusing in a cellulose-based separation medium

    Czech Academy of Sciences Publication Activity Database

    Šalplachta, Jiří; Horká, Marie; Šlais, Karel

    2017-01-01

    Roč. 40, č. 11 (2017), s. 2498-2505 ISSN 1615-9306 R&D Projects: GA MZd(CZ) NV16-29916A; GA ČR(CZ) GA16-03749S; GA MV(CZ) VI20172020069 Institutional support: RVO:68081715 Keywords : isoelectric focusing * preparative * proteins * separation Subject RIV: CB - Analytical Chemistry, Separation OBOR OECD: Analytical chemistry Impact factor: 2.557, year: 2016

  12. Influenza-like illness in Mexico and the United States

    Indian Academy of Sciences (India)

    2009-04-13

    First page Back Continue Last page Graphics. Influenza-like illness in Mexico and the United States. Mexico. First case April 13, 2009 in Mexico. By May 3, 2,498 suspected cases,165 deaths in 31 of 32 States in Mexico. The USA. 24 April 2009. The US reported 7 confirmed human cases of Influenza A/H1N1. Five cases in ...

  13. Dinamika Kelompok Penerima CSR PLN Tarahan Lampung Selatan

    OpenAIRE

    Kusnani, Dedeh Kurniasih; Muljono, Pudji; Saleh, Amiruddin

    2015-01-01

    The study aims to: (1) analyze the level of group dynamics; (2) analyze relation between internal and external characteristics of members and group dynamics. The research uses survey method and was conducted in South Lampung. Numbers of samples are 50 respondents. Descriptive and correlational analysis was used to explain this research. The results of the research show that: (1) the level of group dynamics was low because the group goals are not specific, the structure is not clear, group rol...

  14. Distinct fibrosis pattern in desmosomal and phospholamban mutation carriers in hereditary cardiomyopathies

    NARCIS (Netherlands)

    Sepehrkhouy, Shahrzad; Gho, Johannes M.I.H.; van Es, René; Harakalova, Magdalena; de Jonge, Nicolaas; Dooijes, Dennis; van der Smagt, Jasper J.; Buijsrogge, Marc P.; Hauer, Richard N.W.; Goldschmeding, Roel; de Weger, Roel A.; Asselbergs, Folkert W.; Vink, Aryan

    2017-01-01

    Background Desmosomal and phospholamban (PLN) mutations are associated with arrhythmogenic cardiomyopathy. Ultimately, most cardiomyopathic hearts develop significant cardiac fibrosis. Objective To compare the fibrosis patterns of desmosomal and p. Arg14del PLN–associated cardiomyopathies with the

  15. Myocardial Response to Milrinone in Single Right Ventricle Heart Disease.

    Science.gov (United States)

    Nakano, Stephanie J; Nelson, Penny; Sucharov, Carmen C; Miyamoto, Shelley D

    2016-07-01

    Empiric treatment with milrinone, a phosphodiesterase (PDE) 3 inhibitor, has become increasingly common in patients with single ventricle heart disease of right ventricular (RV) morphology (SRV); our objective was to characterize the myocardial response to PDE3 inhibition (PDE3i) in the pediatric population with SRV. Cyclic adenosine monophosphate levels, PDE activity, and phosphorylated phospholamban (PLN) were determined in explanted human ventricular myocardium from nonfailing pediatric donors (n = 10) and pediatric patients transplanted secondary to SRV. Subjects with SRV were further classified by PDE3i treatment (n = 13 with PDE3i and n = 12 without PDE3i). In comparison with nonfailing RV myocardium (n = 8), cyclic adenosine monophosphate levels are lower in patients with SRV treated with PDE3i (n = 12, P = .021). Chronic PDE3i does not alter total PDE or PDE3 activity in SRV myocardium. Compared with nonfailing RV myocardium, SRV myocardium (both with and without PDE3i) demonstrates equivalent phosphorylated PLN at the protein kinase A phosphorylation site. As evidenced by preserved phosphorylated PLN, the molecular adaptation associated with SRV differs significantly from that demonstrated in pediatric heart failure because of dilated cardiomyopathy. These alterations support a pathophysiologically distinct mechanism of heart failure in pediatric patients with SRV, which has direct implications regarding the presumed response to PDE3i treatment in this population. Copyright © 2016 Elsevier Inc. All rights reserved.

  16. RUMUSAN METODE DETEKSI PENCURIAN LISTRIK MEMANFAATKAN PERANGKAT WSN

    Directory of Open Access Journals (Sweden)

    A Sony

    2017-03-01

    Full Text Available Mendeteksi kasus pencurian listrik di Indonesia memerlukan usaha dan biaya yang besar. PLN saat ini masih menggunakan metode lama dalam mendeteksi kasus pencurian yaitu dengan memeriksa pola tagihan listrik yang didapatkan dari pencatatan secara manual oleh petugas. Penelitian ini mengajukan suatu metode deteksi pencurian listrik dengan memanfaatkan perangkat WSN yang dipasangkan dimeteran pelanggan untuk memonitor jumlah pemakaian listrik. Logika pendeteksian adalah dengan membandingkan data konsumsi pada pelanggan dengan data jumlah listrik yang disalurkan oleh gardu penyalur pada suatu cakupan wilayah. Hasil penelitian berupa simulasi dengan bantuan perangkat lunak Excel, hasil simulasi menunjukkan keefektifan penggunaan metode yang diajukan dengan tingkat akurasi yang tinggi.Detecting theft electricity in Indonesia require enormous amount of efforts and money. PLN until these days still using the old school method to detect this case by checking the pattren of customers electricity bills manualy by the PLN employee. Purposed method in this research is to detect leak of electricity by spreading WSN devices inside each customers meteran to monitor total power consumtion. Logic of the method is compare sum of power consumtion in a testing area with amount of electricity flow in that area by monitor the gardu penyalur conductor. Result of this research is excel simulation, simulation outcome shows that using the purposed to decided system status is effective in the system operational with high accuracy with the actual condition.        

  17. Food hypersensitivity reactions in Soft Coated Wheaten Terriers with protein-losing enteropathy or protein-losing nephropathy or both: gastroscopic food sensitivity testing, dietary provocation, and fecal immunoglobulin E.

    Science.gov (United States)

    Vaden, S L; Hammerberg, B; Davenport, D J; Orton, S M; Trogdon, M M; Melgarejo, L T; VanCamp, S D; Williams, D A

    2000-01-01

    The purpose of this study was to evaluate Soft Coated Wheaten Terriers (SCWTs) affected with protein-losing enteropathy (PLE) or protein-losing nephropathy (PLN) or both for allergy to food. We performed gastroscopic food-sensitivity testing, a provocative dietary trial, and measurement of fecal immunoglobulin E (IgE) in 6 SCWTs affected with PLE or PLN or both. Positive gastroscopic food-sensitivity test reactions were noted in 5 of 6 dogs. Positive reactions were found to milk in 4 dogs, to lamb in 2 dogs, and to wheat and chicken each in 1 dog. Adverse reactions to food (diarrhea, vomiting, or pruritus) were detected in all 6 dogs during the provocative dietary trial. Adverse reactions were found to corn in 5 dogs, to tofu in 3 dogs, to cottage cheese in 2 dogs, to milk in 2 dogs, to farina cream of wheat in 2 dogs, and to lamb in 2 dogs. Serum albumin concentrations significantly decreased and fecal alpha1-protease inhibitor concentration significantly increased 4 days after the provocative trial when compared with baseline values. Antigen-specific fecal IgE varied throughout the provocative trial, with peak levels following ingestion of test meals. We conclude that food hypersensitivities are present in SCWTs affected with the syndrome of PLE/PLN. Mild inflammatory bowel disease was already established in the 6 SCWTs of this report at the time of study, making it impossible to determine if food allergies were the cause or result of the enteric disease.

  18. Conversion of helical tomotherapy plans to step-and-shoot IMRT plans--Pareto front evaluation of plans from a new treatment planning system.

    Science.gov (United States)

    Petersson, Kristoffer; Ceberg, Crister; Engström, Per; Benedek, Hunor; Nilsson, Per; Knöös, Tommy

    2011-06-01

    The resulting plans from a new type of treatment planning system called SharePlan have been studied. This software allows for the conversion of treatment plans generated in a TomoTherapy system for helical delivery, into plans deliverable on C-arm linear accelerators (linacs), which is of particular interest for clinics with a single TomoTherapy unit. The purpose of this work was to evaluate and compare the plans generated in the SharePlan system with the original TomoTherapy plans and with plans produced in our clinical treatment planning system for intensity-modulated radiation therapy (IMRT) on C-arm linacs. In addition, we have analyzed how the agreement between SharePlan and TomoTherapy plans depends on the number of beams and the total number of segments used in the optimization. Optimized plans were generated for three prostate and three head-and-neck (H&N) cases in the TomoTherapy system, and in our clinical treatment planning systems (TPS) used for IMRT planning with step-and-shoot delivery. The TomoTherapy plans were converted into step-and-shoot IMRT plans in SharePlan. For each case, a large number of Pareto optimal plans were created to compare plans generated in SharePlan with plans generated in the Tomotherapy system and in the clinical TPS. In addition, plans were generated in SharePlan for the three head-and-neck cases to evaluate how the plan quality varied with the number of beams used. Plans were also generated with different number of beams and segments for other patient cases. This allowed for an evaluation of how to minimize the number of required segments in the converted IMRT plans without compromising the agreement between them and the original TomoTherapy plans. The plans made in SharePlan were as good as or better than plans from our clinical system, but they were not as good as the original TomoTherapy plans. This was true for both the head-and-neck and the prostate cases, although the differences between the plans for the latter were

  19. Language Planning and Planned Languages: How Can Planned Languages Inform Language Planning?

    Directory of Open Access Journals (Sweden)

    Humphrey Tonkin

    2015-04-01

    Full Text Available The field of language planning (LP has largely ignored planned languages. Of classic descriptions of LP processes, only Tauli (preceded by Wüster suggests that planned languages (what Wüster calls Plansprache might bear on LP theory and practice. If LP aims "to modify the linguistic behaviour of some community for some reason," as Kaplan and Baldauf put it, creating a language de novo is little different. Language policy and planning are increasingly seen as more local and less official, and occasionally more international and cosmopolitan. Zamenhof's work on Esperanto provides extensive material, little studied, documenting the formation of the language and linking it particularly to issues of supranational LP. Defining LP decision-making, Kaplan & Baldauf begin with context and target population. Zamenhof's Esperanto came shortly before Ben-Yehuda's revived Hebrew. His target community was (mostly the world's educated elite; Ben-Yehuda's was worldwide Jewry. Both planners were driven not by linguistic interest but by sociopolitical ideology rooted in reaction to anti-Semitism and imbued with the idea of progress. Their territories had no boundaries, but were not imaginary. Function mattered as much as form (Haugen's terms, status as much as corpus. For Zamenhof, status planning involved emphasis on Esperanto's ownership by its community - a collective planning process embracing all speakers (cf. Hebrew. Corpus planning included a standardized European semantics, lexical selectivity based not simply on standardization but on representation, and the development of written, and literary, style. Esperanto was successful as linguistic system and community language, less as generally accepted lingua franca. Its terminology development and language cultivation offers a model for language revival, but Zamenhof's somewhat limited analysis of language economy left him unprepared to deal with language as power.

  20. Product annotations: AK240885 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK240885 J065029A17 BLASTN AF335504.1 PLN AF335504 Oryza sativa (japonica cultivar-group) hemoglobin... 1 (hb1), hemoglobin 3 (hb3), and hemoglobin 4 (hb4) genes, complete cds. 0.0 ...

  1. A case study of IMRT planning (Plan B) subsequent to a previously treated IMRT plan (Plan A)

    International Nuclear Information System (INIS)

    2Department of Radiation Oncology, Fraser Valley Centre, BC Cancer Agency, Surrey, British Columbia (Canada))" data-affiliation=" (Department of Medical Physics and 2Department of Radiation Oncology, Fraser Valley Centre, BC Cancer Agency, Surrey, British Columbia (Canada))" >Cao, F; 2Department of Radiation Oncology, Fraser Valley Centre, BC Cancer Agency, Surrey, British Columbia (Canada))" data-affiliation=" (Department of Medical Physics and 2Department of Radiation Oncology, Fraser Valley Centre, BC Cancer Agency, Surrey, British Columbia (Canada))" >Leong, C; 2Department of Radiation Oncology, Fraser Valley Centre, BC Cancer Agency, Surrey, British Columbia (Canada))" data-affiliation=" (Department of Medical Physics and 2Department of Radiation Oncology, Fraser Valley Centre, BC Cancer Agency, Surrey, British Columbia (Canada))" >Schroeder, J; 2Department of Radiation Oncology, Fraser Valley Centre, BC Cancer Agency, Surrey, British Columbia (Canada))" data-affiliation=" (Department of Medical Physics and 2Department of Radiation Oncology, Fraser Valley Centre, BC Cancer Agency, Surrey, British Columbia (Canada))" >Lee, B

    2014-01-01

    Background and purpose: Treatment of the contralateral neck after previous ipsilateral intensity modulated radiation therapy (IMRT) for head and neck cancer is a challenging problem. We have developed a technique that limits the cumulative dose to the spinal cord and brainstem while maximizing coverage of a planning target volume (PTV) in the contralateral neck. Our case involves a patient with right tonsil carcinoma who was given ipsilateral IMRT with 70Gy in 35 fractions (Plan A). A left neck recurrence was detected 14 months later. The patient underwent a neck dissection followed by postoperative left neck radiation to a dose of 66 Gy in 33 fractions (Plan B). Materials and Methods: The spinal cord-brainstem margin (SCBM) was defined as the spinal cord and brainstem with a 1.0 cm margin. Plan A was recalculated on the postoperative CT scan but the fluence outside of SCBM was deleted. A further modification of Plan A resulted in a base plan that was summed with Plan B to evaluate the cumulative dose received by the spinal cord and brainstem. Plan B alone was used to evaluate for coverage of the contralateral neck PTV. Results: The maximum cumulative doses to the spinal cord with 0.5cm margin and brainstem with 0.5cm margin were 51.96 Gy and 45.60 Gy respectively. For Plan B, 100% of the prescribed dose covered 95% of PTVb1. Conclusion: The use of a modified ipsilateral IMRT plan as a base plan is an effective way to limit the cumulative dose to the spinal cord and brainstem while enabling coverage of a PTV in the contralateral neck.

  2. Enhancing Emergency Preparedness and Response: Partnering with the Private Business Sector

    Science.gov (United States)

    2009-12-01

    Walmart, the world’s largest retailer, supplied 2,498 trailers of emergency merchandise , opened temporary mobile pharmacies, and used its stores to...World Trade Center (WTC) site over to safety in New Jersey, and restaurants , such as McDonalds, supplying food. Even chefs from local restaurants ...intentions, the unintended consequence leaves businesses unable to receive their routine deliveries of merchandise . The idea appears to be simple

  3. Effects of action planning and coping planning within the theory of planned behaviour

    DEFF Research Database (Denmark)

    Pakpour, Amir H.; Zedi, Isa mohammadi; Chatzisarantis, Nikos

    2011-01-01

    Objective: Patients on dialysis have low physical activity levels. The aim of the study was to examine the validity of action planning and coping planning within the theory of planned behaviour framework, for predicting physical activity behaviour of patients on hemodialysis. Methods: One hundred...... and forty four patients who were undergoing emodialysis were selected from dialysis centers. The mean age of the patients was 56.61 (SD= 11.38) years. The patients completed a questionnaire including variables from the theory of planned behaviour, action planning and coping planning. Physical activity...... was prospectively assessed at 4-weeks with the validated International Physical Activity Questionnaire self-report measure. A hierarchical regression analysis was performed to examine the effects of action planning and coping planning on physical activity behaviour. Results: There was a main effect for coping...

  4. The effect of serum angiotensin II and angiotensin II type 1 receptor ...

    African Journals Online (AJOL)

    Ehab

    2012-06-18

    Jun 18, 2012 ... case-control cross sectional study which included 24 patients with pLN ..... significantly high levels (1000-fold) of Ang II .... initial validation of the Systemic Lupus International ... Fyhrquist F, Metsärinne K, Tikkanen I. Role of.

  5. GenBank blastn search result: AK240885 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK240885 J065029A17 AF335504.1 AF335504 Oryza sativa (japonica cultivar-group) hemoglobin 1 (hb1), hemoglobi...n 3 (hb3), and hemoglobin 4 (hb4) genes, complete cds. PLN 0.0 1 1 ...

  6. GenBank blastx search result: AK241096 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK241096 J065076O13 AF335504.1 AF335504 Oryza sativa (japonica cultivar-group) hemoglobin 1 (hb1), hemoglobi...n 3 (hb3), and hemoglobin 4 (hb4) genes, complete cds. PLN 4e-79 1 ...

  7. GenBank blastx search result: AK240885 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK240885 J065029A17 AF335504.1 AF335504 Oryza sativa (japonica cultivar-group) hemoglobin 1 (hb1), hemoglobi...n 3 (hb3), and hemoglobin 4 (hb4) genes, complete cds. PLN 7e-89 1 ...

  8. Plan Repair as an Extension of Planning

    NARCIS (Netherlands)

    Van der Krogt, R.P.J.; De Weerdt, M.M.

    2005-01-01

    In dynamic environments, agents have to deal with changing situations. In these cases, repairing a plan is often more efficient than planning from scratch, but existing planning techniques are more advanced than existing plan repair techniques. Therefore, we propose a straightforward method to

  9. Automatic planning of head and neck treatment plans

    DEFF Research Database (Denmark)

    Hazell, Irene; Bzdusek, Karl; Kumar, Prashant

    2016-01-01

    radiation dose planning (dosimetrist) and potentially improve the overall plan quality. This study evaluates the performance of the Auto-Planning module that has recently become clinically available in the Pinnacle3 radiation therapy treatment planning system. Twenty-six clinically delivered head and neck...... as the previously delivered clinical plans. For all patients, the Auto-Planning tool produced clinically acceptable head and neck treatment plans without any manual intervention, except for the initial target and OAR delineations. The main benefit of the method is the likely improvement in the overall treatment......Treatment planning is time-consuming and the outcome depends on the person performing the optimization. A system that automates treatment planning could potentially reduce the manual time required for optimization and could also pro-vide a method to reduce the variation between persons performing...

  10. 30 CFR 780.14 - Operation plan: Maps and plans.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Operation plan: Maps and plans. 780.14 Section... PLAN § 780.14 Operation plan: Maps and plans. Each application shall contain maps and plans as follows: (a) The maps and plans shall show the lands proposed to be affected throughout the operation and any...

  11. Stratigrafie a malakofauna holocenní výplně jeskyně Pod valem (Zádielská tiesňava, NP Slovenský kras)

    Czech Academy of Sciences Publication Activity Database

    Ložek, Vojen

    2011-01-01

    Roč. 2010, - (2011), s. 62-65 ISSN 0514-8057 Institutional research plan: CEZ:AV0Z30130516 Keywords : Slovak Karst * cave fill * extreme habitat * Holocene * Mollusca * Zebrina detrita Subject RIV: DB - Geology ; Mineralogy http://www.geology.cz/zpravy/obsah/2010/zpravy-2010-14.pdf

  12. Managing Assets Of Agricultural Property Of The National Treasury In The Context Of State Aid Granted By The Agricultural Property Agency

    Directory of Open Access Journals (Sweden)

    Lizińska Wiesława

    2015-09-01

    Full Text Available This study covers the issue of activities of the Agricultural Property Agency in terms of state aid in the form of non-repayable financial aid, with the following specific objectives: determining the scale and diversity of state aid granted by the APA (including the local branch in Olsztyn, evaluating the current technical condition of some of the assets and their condition upon being handed over by the APA, determining their importance, main problems associated with resources which are taken over, identifying and assessing the importance of actions which encourage communes to take over property still held by the APA, assessing the scale and procedure of aid granted in the opinion of representatives of APA units. The article makes use of information obtained from the local branch of the APA in Olsztyn in the years 2003-2014. A direct survey among the entities was taken. The survey questionnaire was sent in 2014 to all communes (gminas of the Province (Voivodeship of Warmia and Mazury (116 units. Completed questionnaires were returned by 73 representatives of the communes. A total of PLN 327.1 million was allotted in the Agency’s financial plans for the program of non-repayable financial aid during the period from 2009 to 2014. Approximately 81.6% of PLN 164.4 million granted by the local branch of the APA in Olsztyn, was granted to units of the public finance sector. As was shown in the survey conducted among representatives of local governments, the interest of communes in taking over assets still held by2 the local branch of the APA in Olsztyn could be increased by limiting the number of tenants who do not pay the rent regularly and by increasing the amount of non-repayable financial aid. It is possible to carry out the latter action, but the former could prove to be extremely difficult.

  13. GenBank blastn search result: AK241681 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK241681 J065193N01 AF335504.1 AF335504 Oryza sativa (japonica cultivar-group) hemoglobin 1 (hb1), hemoglobi...n 3 (hb3), and hemoglobin 4 (hb4) genes, complete cds. PLN 3e-34 1 1 ...

  14. GenBank blastn search result: AK318581 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK318581 J090090I16 AF335504.1 AF335504 Oryza sativa (japonica cultivar-group) hemoglobin 1 (hb1), hemoglobi...n 3 (hb3), and hemoglobin 4 (hb4) genes, complete cds. PLN 1e-23 1 -1 ...

  15. GenBank blastn search result: AK241096 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK241096 J065076O13 AF335504.1 AF335504 Oryza sativa (japonica cultivar-group) hemoglobin 1 (hb1), hemoglobi...n 3 (hb3), and hemoglobin 4 (hb4) genes, complete cds. PLN 6e-56 1 1 ...

  16. GenBank blastn search result: AK289024 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK289024 J090090I16 AF335504.1 AF335504 Oryza sativa (japonica cultivar-group) hemoglobin 1 (hb1), hemoglobi...n 3 (hb3), and hemoglobin 4 (hb4) genes, complete cds. PLN 9e-24 1 -1 ...

  17. [Outsourcing: theory and practice at a clinical hospital in Szczecin exemplified by medical waste transport and treatment service].

    Science.gov (United States)

    Kotlega, Dariusz; Nowacki, Przemysław; Lewiński, Dariusz; Chmurowicz, Ryszard; Ciećwiez, Sylwester

    2011-01-01

    Outsourcing proves to be a useful tool in the difficult process of improving the financial result of hospitals. Outsourcing means separation of some functions and services in one entity and their transfer to another. The aim of this study was to analyze the use of outsourcing at the Second Independent Public University Hospital of the Pomeranian Medical University (SPSK 2 PUM) in Szczecin. We studied the transport and treatment of medical waste. Outsourcing of waste treatment services led to financial savings. The cost of treatment of one kilogram of waste by an external company was PLN 2.53. The same service provided by the hospital would cost approximately PLN 7 per kilogram. Appropriate attention should be paid to the quality of services. It seems useful to have appropriate tools for quality control and monitoring. SPSK 2 PUM can serve as a good example of effective use of outsourcing.

  18. Which characteristics of planning matter? Individual and dyadic physical activity plans and their effects on plan enactment.

    Science.gov (United States)

    Keller, Jan; Fleig, Lena; Hohl, Diana Hilda; Wiedemann, Amelie U; Burkert, Silke; Luszczynska, Aleksandra; Knoll, Nina

    2017-09-01

    Past research supports individual planning as an effective intervention strategy to increase physical activity in individuals. A similar strategy, dyadic planning, adds a planning partner who supports an individual's planning processes. Whether the two planning formats differ in terms of participants' entered plan content and whether and how different content characteristics are linked to plan enactment remains unknown. By investigating the content of generated plans, this study aimed at distinguishing plan characteristics of the two planning formats and examining their role as predictors of later plan enactment. Secondary analyses of a three-arm RCT with German couples (data collection between 2013 and 2015). Couples were assigned to an individual (IPC, n = 114) or dyadic planning condition (DPC, n = 111) and formulated up to 5 physical activity plans for a target person. Couples assigned to a control condition were not included as they did not generate plans. The following characteristics were distinguished and coded for each plan: number of planned opportunities, presence of a planned routine, planned cue- or activity-related specificity, activity-related intensity, and chronological plan rank. One week before (T0) and two weeks following (T2) the intervention (T1), increase vs. no increase of the planned activity was coded as a dichotomous plan enactment variable. Multilevel logistic regressions were fit. Plan enactment was higher in dyadic than in individual planners. Findings indicated that routines (e.g., after work) were positively related to plan enactment, whereas a high specificity of when-cues (e.g., Friday at 6.30 p.m.) showed a negative relationship. None of the examined plan characteristics could explain differences in enactment between IPC and DPC. Linking health behaviours to other behavioural routines seems beneficial for subsequent plan enactment. Dyadic planning was linked with higher enactment rates than individual planning. However, as

  19. 30 CFR 784.23 - Operation plan: Maps and plans.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Operation plan: Maps and plans. 784.23 Section... PLAN § 784.23 Operation plan: Maps and plans. Each application shall contain maps and plans as follows... INTERIOR SURFACE COAL MINING AND RECLAMATION OPERATIONS PERMITS AND COAL EXPLORATION SYSTEMS UNDER...

  20. Clostridium butyricum CGMCC0313.1 Protects against Autoimmune Diabetes by Modulating Intestinal Immune Homeostasis and Inducing Pancreatic Regulatory T Cells

    Directory of Open Access Journals (Sweden)

    Lingling Jia

    2017-10-01

    Full Text Available Recent evidence indicates that indigenous Clostridium species induce colonic regulatory T cells (Tregs, and gut lymphocytes are able to migrate to pancreatic islets in an inflammatory environment. Thus, we speculate that supplementation with the well-characterized probiotics Clostridium butyricum CGMCC0313.1 (CB0313.1 may induce pancreatic Tregs and consequently inhibit the diabetes incidence in non-obese diabetic (NOD mice. CB0313.1 was administered daily to female NOD mice from 3 to 45 weeks of age. The control group received an equal volume of sterile water. Fasting glucose was measured twice a week. Pyrosequencing of the gut microbiota and flow cytometry of mesenteric lymph node (MLN, pancreatic lymph node (PLN, pancreatic and splenic immune cells were performed to investigate the effect of CB0313.1 treatment. Early oral administration of CB0313.1 mitigated insulitis, delayed the onset of diabetes, and improved energy metabolic dysfunction. Protection may involve increased Tregs, rebalanced Th1/Th2/Th17 cells and changes to a less proinflammatory immunological milieu in the gut, PLN, and pancreas. An increase of α4β7+ (the gut homing receptor Tregs in the PLN suggests that the mechanism may involve increased migration of gut-primed Tregs to the pancreas. Furthermore, 16S rRNA gene sequencing revealed that CB0313.1 enhanced the Firmicutes/Bacteroidetes ratio, enriched Clostridium-subgroups and butyrate-producing bacteria subgroups. Our results provide the basis for future clinical investigations in preventing type 1 diabetes by oral CB0313.1 administration.

  1. Growth and characterization of Pb(Lu{sub 1/2}Nb{sub 1/2})O{sub 3}-Pb(Mg{sub 1/3}Nb{sub 2/3})O{sub 3}-PbTiO{sub 3} ternary piezo-/ferroelectric crystals

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Ying [Key Laboratory of Optoelectronic Materials Chemistry and Physics, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 350002 (China); College of Physics and Energy, Fujian Normal University, Fuzhou, Fujian 350117 (China); He, Chao [Key Laboratory of Optoelectronic Materials Chemistry and Physics, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 350002 (China); Yang, Xiaoming [Key Laboratory of Optoelectronic Materials Chemistry and Physics, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 350002 (China); College of Physics and Energy, Fujian Normal University, Fuzhou, Fujian 350117 (China); Li, Xiuzhi; Wang, Zujian [Key Laboratory of Optoelectronic Materials Chemistry and Physics, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 350002 (China); Huang, Zhigao; Lai, Fachun [College of Physics and Energy, Fujian Normal University, Fuzhou, Fujian 350117 (China); Long, Xifa, E-mail: lxf@fjirsm.ac.cn [Key Laboratory of Optoelectronic Materials Chemistry and Physics, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 350002 (China)

    2016-08-05

    Piezo-/ferroelectric crystals of Pb(Lu{sub 1/2}Nb{sub 1/2})O{sub 3}-Pb(Mg{sub 1/3}Nb{sub 2/3})O{sub 3}-PbTiO{sub 3} ternary solid solution system with high Curie temperature, in the vicinity of morphotropic phase boundary (MPB) region, are grown by the top-seeded solution growth (TSSG) method for the first time. The compositions and structures of the crystals are analyzed, all the structures are found to have pure perovskite structure using X-ray diffraction analysis. Di-/piezo-/ferroelectric properties of the crystals are also characterized systematically. The Curie temperature T{sub c} and coercive field E{sub c}, increase gradually with increasing PbTiO{sub 3} content. In particular, the crystal with composition 0.34PLN-0.31PMN-0.35PT possesses excellent electric properties including the Curie temperature, the rhombohedral–tetragonal phase transition temperature, the piezoelectric coefficient, the remnant polarization and the coercive field, which are T{sub c} = 228 °C, T{sub RT} = 156 °C, d{sub 33} = 2092 pC N{sup −1}, Pr = 35.5 μC cm{sup −2} and E{sub c} = 8.1 kV cm{sup −1}, respectively, making it a promising material for transducers or detectors in a wide temperature range. - Highlights: • PLN-PMN-PT Piezo-/ferroelectric crystals are grown by TSSG method. • The Curie temperature and coercive field increase gradually with increasing PT. • The crystal of 0.34PLN-0.31PMN-0.35PT possesses excellent electric properties.

  2. Induction of bacteriocin production by coculture is widespread among plantaricin-producing Lactobacillus plantarum strains with different regulatory operons.

    Science.gov (United States)

    Maldonado-Barragán, Antonio; Caballero-Guerrero, Belén; Lucena-Padrós, Helena; Ruiz-Barba, José Luis

    2013-02-01

    We describe the bacteriocin-production phenotype in a group of eight singular bacteriocinogenic Lactobacillus plantarum strains with three distinct genotypes regarding the plantaricin locus. Genotyping of these strains revealed the existence of two different plantaricin-production regulatory operons, plNC8-plNC8HK-plnD or plnABCD, involving three-component systems controlled each of them by a specific autoinducer peptide (AIP), i.e. PLNC8IF or PlnA. While all of the strains produced antimicrobial activity when growing on solid medium, most of them halted this production when cultured in broth, thus reflecting the functionality of regulatory mechanisms. Antimicrobial activity in broth cultures was re-established or enhanced when the specific AIP was added to the culture or by coculturing with specific bacterial strains. The latter trait appeared to be widespread in bacteriocinogenic L. plantarum strains independently of the regulatory system used to regulate bacteriocin production or the specific bacteriocins produced. The induction spectrum through coculture, i.e. the pattern of bacterial strains able to induce bacteriocin production, was characteristic of each individual L. plantarum strain. Also, the ability of some bacteria to induce bacteriocin production in L. plantarum by coculture appeared to be strain specific. The fact that induction of bacteriocin production by coculturing appeared to be a common feature in L. plantarum can be exploited accordingly to enhance the viability of this species in food and feed fermentations, as well as to contribute to probiotic functionality when colonising the gastrointestinal tract. Copyright © 2012 Elsevier Ltd. All rights reserved.

  3. Identifying Clinical Factors Which Predict for Early Failure Patterns Following Resection for Pancreatic Adenocarcinoma in Patients Who Received Adjuvant Chemotherapy Without Chemoradiation.

    Science.gov (United States)

    Walston, Steve; Salloum, Joseph; Grieco, Carmine; Wuthrick, Evan; Diaz, Dayssy A; Barney, Christian; Manilchuk, Andrei; Schmidt, Carl; Dillhoff, Mary; Pawlik, Timothy M; Williams, Terence M

    2018-05-04

    The role of radiation therapy (RT) in resected pancreatic cancer (PC) remains incompletely defined. We sought to determine clinical variables which predict for local-regional recurrence (LRR) to help select patients for adjuvant RT. We identified 73 patients with PC who underwent resection and adjuvant gemcitabine-based chemotherapy alone. We performed detailed radiologic analysis of first patterns of failure. LRR was defined as recurrence of PC within standard postoperative radiation volumes. Univariate analyses (UVA) were conducted using the Kaplan-Meier method and multivariate analyses (MVA) utilized the Cox proportional hazard ratio model. Factors significant on UVA were used for MVA. At median follow-up of 20 months, rates of local-regional recurrence only (LRRO) were 24.7%, LRR as a component of any failure 68.5%, metastatic recurrence (MR) as a component of any failure 65.8%, and overall disease recurrence (OR) 90.5%. On UVA, elevated postoperative CA 19-9 (>90 U/mL), pathologic lymph node positive (pLN+) disease, and higher tumor grade were associated with increased LRR, MR, and OR. On MVA, elevated postoperative CA 19-9 and pLN+ were associated with increased MR and OR. In addition, positive resection margin was associated with increased LRRO on both UVA and MVA. About 25% of patients with PC treated without adjuvant RT develop LRRO as initial failure. The only independent predictor of LRRO was positive margin, while elevated postoperative CA 19-9 and pLN+ were associated with predicting MR and overall survival. These data may help determine which patients benefit from intensification of local therapy with radiation.

  4. Strategic planning: the first step in the planning process.

    Science.gov (United States)

    Gelinas, Marc A

    2003-01-01

    Strategic planning is a systematic process through which an organization builds commitment among key stakeholders to goals and priorities which are essential to its mission and vision, and responsive to the operating environment. Strategic planning is the first step in a comprehensive planning process that also includes business planning and implementation planning. If all three steps are carried out in sequence, strategic planning can be a very effective means of educating the stakeholders about where the cancer program is and where it is going, gaining support and commitment for the direction that the cancer program will take, and assuring that everyone's expectations can be managed effectively. Unfortunately, some organizations and cancer program leaders misunderstand the process. Too often, strategic planning is used as a stand-alone activity. This article will describe what strategic planning is, how it should smoothly lead into business planning and implementation planning, and how to avoid the pitfalls that sometimes arise during the strategic planning effort.

  5. AGR-2 Data Qualification Report for ATR Cycles 147A, 148A, 148B, and 149A

    International Nuclear Information System (INIS)

    Abbott, Michael L.; Daum, Keith A.

    2011-01-01

    This report presents the data qualification status of fuel irradiation data from the first four reactor cycles (147A, 148A, 148B, and 149A) of the on-going second Advanced Gas Reactor (AGR-2) experiment as recorded in the NGNP Data Management and Analysis System (NDMAS). This includes data received by NDMAS from the period June 22, 2010 through May 21, 2011. AGR-2 is the second in a series of eight planned irradiation experiments for the AGR Fuel Development and Qualification Program, which supports development of the very high temperature gas-cooled reactor (VHTR) under the Next Generation Nuclear Plant (NGNP) Project. Irradiation of the AGR-2 test train is being performed at the Advanced Test Reactor (ATR) at the Idaho National Laboratory (INL) and is planned for 600 effective full power days (approximately 2.75 calendar years) (PLN-3798). The experiment is intended to demonstrate the performance of UCO (uranium oxycarbide) and UO2 (uranium dioxide) fuel produced in a large coater. Data qualification status of the AGR-1 experiment was reported in INL/EXT-10-17943 (Abbott et al. 2010).

  6. AGR-2 Data Qualification Report for ATR Cycles 147A, 148A, 148B, and 149A

    Energy Technology Data Exchange (ETDEWEB)

    Michael L. Abbott; Keith A. Daum

    2011-08-01

    This report presents the data qualification status of fuel irradiation data from the first four reactor cycles (147A, 148A, 148B, and 149A) of the on-going second Advanced Gas Reactor (AGR-2) experiment as recorded in the NGNP Data Management and Analysis System (NDMAS). This includes data received by NDMAS from the period June 22, 2010 through May 21, 2011. AGR-2 is the second in a series of eight planned irradiation experiments for the AGR Fuel Development and Qualification Program, which supports development of the very high temperature gas-cooled reactor (VHTR) under the Next Generation Nuclear Plant (NGNP) Project. Irradiation of the AGR-2 test train is being performed at the Advanced Test Reactor (ATR) at the Idaho National Laboratory (INL) and is planned for 600 effective full power days (approximately 2.75 calendar years) (PLN-3798). The experiment is intended to demonstrate the performance of UCO (uranium oxycarbide) and UO2 (uranium dioxide) fuel produced in a large coater. Data qualification status of the AGR-1 experiment was reported in INL/EXT-10-17943 (Abbott et al. 2010).

  7. Quality Assurance Project Plan for Facility Effluent Monitoring Plan activities

    International Nuclear Information System (INIS)

    Nickels, J.M.

    1991-06-01

    This Quality Assurance Project Plan addresses the quality assurance requirements for the Facility Monitoring Plans of the overall site-wide environmental monitoring plan. This plan specifically applies to the sampling and analysis activities and continuous monitoring performed for all Facility Effluent Monitoring Plan activities conducted by Westinghouse Hanford Company. It is generic in approach and will be implemented in conjunction with the specific requirements of individual Facility Effluent Monitoring Plans. This document is intended to be a basic road map to the Facility Effluent Monitoring Plan documents (i.e., the guidance document for preparing Facility Effluent Monitoring Plans, Facility Effluent Monitoring Plan determinations, management plan, and Facility Effluent Monitoring Plans). The implementing procedures, plans, and instructions are appropriate for the control of effluent monitoring plans requiring compliance with US Department of Energy, US Environmental Protection Agency, state, and local requirements. This Quality Assurance Project Plan contains a matrix of organizational responsibilities, procedural resources from facility or site manuals used in the Facility Effluent Monitoring Plans, and a list of the analytes of interest and analytical methods for each facility preparing a Facility Effluent Monitoring Plan. 44 refs., 1 figs., 2 tabs

  8. Epistemic Planning

    DEFF Research Database (Denmark)

    Baral, Chitta; Bolander, Thomas; van Ditmarsch, Hans

    The seminar Epistemic Planning brought together the research communities of Dynamic Epistemic Logic, Knowledge Representation and Reasoning, and Automated Planning to address fundamental problems on the topic of epistemic planning. In the context of this seminar, dynamic epistemic logic...... investigates the formal semantics of communication and communicative actions, knowledge representation and reasoning focuses on theories of action and change, and automated planning investigates computational techniques and tools to generate plans. The original goals of the seminar were to develop benchmarks...... for epistemic planning, to explore the relationship between knowledge and belief in multi-agent epistemic planning, to develop models of agency and capability in epistemic planning and to explore action types and their representations (these originally separate goals were merged during the seminar), and finally...

  9. Teaching planning theory as planner roles in urban planning education

    DEFF Research Database (Denmark)

    Olesen, Kristian

    2018-01-01

    Planning theory is often portrayed as a subject that urban planning students find too abstract and fail to see the relevance of. This paper advocates the perspective that planning theory can be made more student-friendly. This requires, firstly, that academic discussions about the relevance...... of planning theory for urban planning practice are integrated into the course module. If students are to appreciate planning theory, it requires that they understand how planning theory can inspire planning practice. Secondly, it requires careful considerations to the pedagogy of planning theory. The paper...... suggests that teaching planning theory as a variety of planner roles offers a helpful pedagogical approach for helping students construct their identities as urban planners. The paper builds on the author’s own experiences of teaching planning theory in a master’s urban planning programme, and has been...

  10. Self-interested Planning Agents using Plan Repair

    NARCIS (Netherlands)

    Van der Krogt, R.P.J.; De Weerdt, M.M.

    2005-01-01

    We present a novel approach to multiagent planning for selfinterested agents. The main idea behind our approach is that multiagent planning systems should be built upon (singleagent) plan repair systems. In our system agents can exchange goals and subgoals through an auction, using their own

  11. Self-interested planning agents using plan repair

    NARCIS (Netherlands)

    R.P.J. van der Krogt; M.M. de Weerdt (Mathijs)

    2005-01-01

    htmlabstractWe present a novel approach to multiagent planning for selfinterested agents. The main idea behind our approach is that multiagent planning systems should be built upon (singleagent) plan repair systems. In our system agents can exchange goals and subgoals through an auction, using

  12. Optimization of Electricity Generation Schemes in the Java-Bali Grid System with Co2 Reduction Consideration

    Directory of Open Access Journals (Sweden)

    Farizal Farizal

    2016-08-01

    Full Text Available This research considers the problem of reducing CO2 emissions from the Java-Bali power grid system that consists of a variety of power-generating plants: coal-fired, natural gas, oil, and renewable energy (PV, geothermal, hydroelectric, wind, and landfill gas. The problem is formulated as linear programming and solved using LINGO 10. The model was developed for a nation to meet a specified CO2 emission target. Two carbon dioxide mitigation options are considered in this study, i.e. fuel balancing and fuel switching. In order to reduce the CO2 emissions by 26% in 2021, State Electric Supply Company (PLN has to generate up to 30% of electricity from renewable energy (RE, and the cost of electricity (COE is expected to increase to 617.77 IDR per kWh for a fuel balancing option, while for fuel switching option, PLN has to generate 29% of electricity from RE, and the COE is expected to increase to 535.85 IDR per kWh.

  13. Creation and Valuation of Instruments Compensating Lower Share Prices with the Help of Black–Scholes Formula

    Directory of Open Access Journals (Sweden)

    Zaremba Leszek

    2017-02-01

    Full Text Available In this paper, we present a 1-period model of the Polish financial market from the view point of KGHM, the Polish largest listed company that suffered huge declines in share prices from 125 PLN in August 2015 to 60 PLN in January 2015. Our goal is to show how KGHM might create a portfolio (with practically zero cost, which would fully compensate the abovementioned declines. The methodology presented below may be equally well employed by many other listed companies and investment funds, as well. We create here a matrix model of the Polish financial market and employ the Black-Scholes formula to valuate portfolios compensating potential declines of KGHM’s shares prices. To give more insight to practitioners wishing to apply the results presented here to other listed companies, we distinguish two cases. In one of them, volatility of KGHM’s share prices is 20%, and in the other case it equals 33%.

  14. Modeling And Simulation Of Electrical Prevenion System Using Arduino Uno,Gsm Modem, And Acs712 Current Sensor

    Science.gov (United States)

    Khair, Ummul; Jabbar Lubis, Abdul; Agustha, Indra; Dharmawati; Zulfin, M.

    2017-12-01

    The current electricity needs is very primary, all objects including electronics require power, it encourages people not to be able to save electricity so the theft of electric power would be done. The use of ACS712 current sensor as the sensor with arduino uno would find out the power consumption continuously and prevent the theft of electricity because of the use of electricity which has been determined by PLN and the people fetl that it is not enough for every house, so the author made a tool for prevention of theft of electric power by using the arduino uno, buzzer, ACS712 current sensor, lcd, and relay then the power usage can be controlled according to the use to prevent the occurrence of theft of electricity so the use can be seen directly on the lcd 16x2and GSM modem to give information to employees of PLN so that it can reduceelectrical theft by the public.

  15. Conserved domains and SINE diversity during animal evolution.

    Science.gov (United States)

    Luchetti, Andrea; Mantovani, Barbara

    2013-10-01

    Eukaryotic genomes harbour a number of mobile genetic elements (MGEs); moving from one genomic location to another, they are known to impact on the host genome. Short interspersed elements (SINEs) are well-represented, non-autonomous retroelements and they are likely the most diversified MGEs. In some instances, sequence domains conserved across unrelated SINEs have been identified; remarkably, one of these, called Nin, has been conserved since the Radiata-Bilateria splitting. Here we report on two new domains: Inv, derived from Nin, identified in insects and in deuterostomes, and Pln, restricted to polyneopteran insects. The identification of Inv and Pln sequences allowed us to retrieve new SINEs, two in insects and one in a hemichordate. The diverse structural combination of the different domains in different SINE families, during metazoan evolution, offers a clearer view of SINE diversity and their frequent de novo emergence through module exchange, possibly underlying the high evolutionary success of SINEs. © 2013 Elsevier Inc. All rights reserved.

  16. Practical planning extending the classical AI planning paradigm

    CERN Document Server

    Wilkins, David E

    2014-01-01

    Planning, or reasoning about actions, is a fundamental element of intelligent behavior--and one that artificial intelligence has found very difficult to implement. The most well-understood approach to building planning systems has been under refinement since the late 1960s and has now reached a level of maturity where there are good prospects for building working planners. Practical Planning is an in-depth examination of this classical planning paradigm through an intensive case study of SIPE, a significantly implemented planning system. The author, the developer of SIPE, defines the plann

  17. INFORMATION SYSTEM STRATEGIC PLANNING WITH ENTERPRISE ARCHITECTURE PLANNING

    Directory of Open Access Journals (Sweden)

    Lola Yorita Astri

    2013-05-01

    Full Text Available An integrated information system is needed in an enterprise to support businessprocesses run by an enterprise. Therefore, to develop information system can use enterprisearchitecture approach which can define strategic planning of enterprise information system. SMPNegeri 1 Jambi can be viewed as an enterprise because there are entities that should be managedthrough an integrated information system. Since there has been no unification of different elementsin a unity yet, enterprise architecture model using Enterprise Architecture Planning (EAP isneeded which will obtain strategic planning of enterprise information system in SMP Negeri 1Jambi. The goal of strategic planning of information system with Enterprise Architecture Planning(EAP is to define primary activities run by SMP Negeri 1 Jambi and support activities supportingprimary activities. They can be used as a basis for making data architecture which is the entities ofapplication architecture. At last, technology architecture is designed to describe technology neededto provide environment for data application. The plan of implementation is the activity plan madeto implemented architectures by enterprise.

  18. 11. Strategic planning.

    Science.gov (United States)

    2014-05-01

    There are several types of planning processes and plans, including strategic, operational, tactical, and contingency. For this document, operational planning includes tactical planning. This chapter examines the strategic planning process and includes an introduction into disaster response plans. "A strategic plan is an outline of steps designed with the goals of the entire organisation as a whole in mind, rather than with the goals of specific divisions or departments". Strategic planning includes all measures taken to provide a broad picture of what must be achieved and in which order, including how to organise a system capable of achieving the overall goals. Strategic planning often is done pre-event, based on previous experience and expertise. The strategic planning for disasters converts needs into a strategic plan of action. Strategic plans detail the goals that must be achieved. The process of converting needs into plans has been deconstructed into its components and includes consideration of: (1) disaster response plans; (2) interventions underway or planned; (3) available resources; (4) current status vs. pre-event status; (5) history and experience of the planners; and (6) access to the affected population. These factors are tempered by the local: (a) geography; (b) climate; (c) culture; (d) safety; and (e) practicality. The planning process consumes resources (costs). All plans must be adapted to the actual conditions--things never happen exactly as planned.

  19. Role of common and rare variants in SCN10A

    DEFF Research Database (Denmark)

    Behr, Elijah R.; Savio-Galimberti, Eleonora; Barc, Julien

    2015-01-01

    AIMS: Brugada syndrome (BrS) remains genetically heterogeneous and is associated with slowed cardiac conduction. We aimed to identify genetic variation in BrS cases at loci associated with QRS duration. METHODS AND RESULTS: A multi-centre study sequenced seven candidate genes (SCN10A, HAND1, PLN,...

  20. Intersection planning in Safer Transportation Network Planning : safety principles, planning framework, and library information.

    NARCIS (Netherlands)

    Hummel, T.

    2001-01-01

    This report is one in a series of publications, used in the development of the network planning tool ‘Safer Transportation Network Planning’ (Safer-TNP). The publications were used to guide the development of planning structures, diagnostic tools, planning recommendations, and research information

  1. National Waste Terminal Storage Program: planning and control plan. Volume II. Plan description

    International Nuclear Information System (INIS)

    1977-05-01

    Objective of the NWTS program planning and control plan is to provide the information necessary for timely and effective OWI management decisions. Purpose is to describe the concepts and techniques that will be utilized by OWI to establish structured, completely planned and controlled technical, cost, and schedule NWTS baselines from which performance or progress can be accurately measured

  2. OCRWM's evolving strategic planning process and the 1990 plan

    International Nuclear Information System (INIS)

    Sprecher, W.M.; Munro, J.F.; Champagne, D.L.

    1991-01-01

    In 1990, the Secretary of Energy (Secretary Watkins) ordered that all 23 of the Department's major organizations adopt systems of strategic planning. This paper explains the strategic planning process being adopted by one of those organizations, the Office of Civilian Radioactive Waste Management (OCRWM). Secretary Watkins also ordered a much-abbreviated planning cycle for 1990 to produce the first set of plans in September. That first plan for OCRWM is also discussed here

  3. 76 FR 45606 - Desert Renewable Energy Conservation Plan, Habitat Conservation Plan and Possible Land Use Plan...

    Science.gov (United States)

    2011-07-29

    ...-N131; 80221-1112-80221-F2] Desert Renewable Energy Conservation Plan, Habitat Conservation Plan and Possible Land Use Plan Amendment, Southern California: Environmental Impact Statement AGENCY: Fish and..., as amended, for the proposed Desert Renewable Energy Conservation Plan (DRECP). The EIS will be a...

  4. 1994 Site Development Plan: A plan with vision

    Energy Technology Data Exchange (ETDEWEB)

    1994-07-01

    The 1994 Lawrence Livermore National Laboratory Site Development Plan has been developed during a period of great change and uncertainty. Our goal is to make possible the best use of the Laboratory`s resources to meet shifting national priorities in the post-Cold War world. Site Planning is an important component of the overall Laboratory strategic planning process. This plan focuses on opportunities for the Laboratory as well as on key site development issues including facility construction, redevelopment and reuse, site accessibility, and security. A major challenge is to achieve sufficient stability in the site planning and execution so that the processes of construction can occur efficiently while at the same time providing sufficient flexibility in site facilities so that a range of changing national needs can be accommodated. We are closely coupled to the DOE strategic planning process to meet this challenge.

  5. Conditional Epistemic Planning

    DEFF Research Database (Denmark)

    Andersen, Mikkel Birkegaard; Bolander, Thomas; Jensen, Martin Holm

    2012-01-01

    Recent work has shown that Dynamic Epistemic Logic (DEL) offers a solid foundation for automated planning under partial observability and non-determinism. Under such circumstances, a plan must branch if it is to guarantee achieving the goal under all contingencies (strong planning). Without...... branching, plans can offer only the possibility of achieving the goal (weak planning). We show how to formulate planning in uncertain domains using DEL and give a language of conditional plans. Translating this language to standard DEL gives verification of both strong and weak plans via model checking....... In addition to plan verification, we provide a tableau-inspired algorithm for synthesising plans, and show this algorithm to be terminating, sound and complete....

  6. Community development planning

    International Nuclear Information System (INIS)

    Gray, S.I.

    1983-01-01

    The focus of this paper will be methods of local community involvement in the community development planning efforts which will be required at the recommended sites. Community development planning will include capital improvement plans, housing plans, zoning changes, business development plans and other community service and fiscal plans required to meet the projected needs of new residents as a result of the repository construction and operation. This paper will present, (1) the need for community planning, (2) methods of responding to community planning needs, (3) current community planning issues to be addressed. 2 references, 1 figure

  7. Identification of Structural and Immunity Genes of a Class IIb Bacteriocin Encoded in the Enterocin A Operon of Enterococcus faecium Strain MXVK29.

    Science.gov (United States)

    Escamilla-Martínez, E E; Cisneros, Y M Álvarez; Fernández, F J; Quirasco-Baruch, M; Ponce-Alquicira, E

    2017-10-09

    The Enterococcus faecium strain MXVK29, isolated from fermented sausages, produces a bacteriocin with a molecular mass of 3.5 kDa that belongs to the class of enterocins II.1, according to the terminal amino acid sequence, and has been identified as enterocin A. This bacteriocin is active against selected strains of Listeria, Staphylococcus, Pediococcus, and Enterococcus. In this study, we identified the genes adjacent to the structural gene for this bacteriocin, such as the immunity gene (entI) and the inducer gene (entF). Accessory genes for this bacteriocin, such as entK, entR, and entT, were identified as well, in addition to the orf2 and orf3, showing a high identity with class IIb peptides bacteriocins. The orf2 shows the consensus motif GxxxG, similar to those shown by bacteriocins such as PlnNC8α, EntCα, and Ent1071A, whereas orf3 shows a consensus motif SxxxS similar to that present in PlnNC8β (AxxxA). PlnNC8 is expressed only in bacterial cocultures, so there is the possibility that the expression of this two-peptide bacteriocin can be induced by a similar mechanism. So far, only the expression of enterocin A has been found in this strain; however, the presence of the genes ent29α and ent29β opens the possibility for further research on its induction, functionality, and origin. Although there are reports on this type of bacteriocin (EntX, EntC, and Ent1071) in other strains of E. faecium, no report exists yet on an Enterococcus strain producing two different classes of bacteriocin.

  8. Comparison study on models for calculation of NPP’s levelized unit electricity cost

    International Nuclear Information System (INIS)

    Nuryanti; Mochamad Nasrullah; Suparman

    2014-01-01

    Economic analysis that is generally done through the calculation of Levelized Unit Electricity Cost (LUEC) is crucial to be done prior to any investment decision on the nuclear power plant (NPP) project. There are several models that can be used to calculate LUEC, which are: R&D PT. PLN (Persero) Model, Mini G4ECONS model and Levelized Cost model. This study aimed to perform a comparison between the three models. Comparison technique was done by tracking the similarity used for each model and then given a case of LUEC calculation for SMR NPP 2 x 100 MW using these models. The result showed that the R&D PT. PLN (Persero) Model have a common principle with Mini G4ECONS model, which use Capital Recovery Factor (CRF) to discount the investment cost which eventually become annuity value along the life of plant. LUEC on both models is calculated by dividing the sum of the annual investment cost and the cost for operating NPP with an annual electricity production.While Levelized Cost model based on the annual cash flow. Total of annual costs and annual electricity production were discounted to the first year of construction in order to obtain the total discounted annual cost and the total discounted energy generation. LUEC was obtained by dividing both of the discounted values. LUEC calculations on the three models produce LUEC value, which are: 14.5942 cents US$/kWh for R&D PT. PLN (Persero) Model, 15.056 cents US$/kWh for Mini G4ECONs model and 14.240 cents US$/kWh for Levelized Cost model. (author)

  9. PlanJury: probabilistic plan evaluation revisited

    Science.gov (United States)

    Witte, M.; Sonke, J.-J.; van Herk, M.

    2014-03-01

    Purpose: Over a decade ago, the 'Van Herk margin recipe paper' introduced plan evaluation through DVH statistics based on population distributions of systematic and random errors. We extended this work for structures with correlated uncertainties (e.g. lymph nodes or parotid glands), and considered treatment plans containing multiple (overlapping) dose distributions (e.g. conventional lymph node and hypo-fractionated tumor doses) for which different image guidance protocols may lead to correlated errors. Methods: A command-line software tool 'PlanJury' was developed which reads 3D dose and structure data exported from a treatment planning system. Uncertainties are specified by standard deviations and correlation coefficients. Parameters control the DVH statistics to be computed: e.g. the probability of reaching a DVH constraint, or the dose absorbed at given confidence in a (combined) volume. Code was written in C++ and parallelized using OpenMP. Testing geometries were constructed using idealized spherical volumes and dose distributions. Results: Negligible stochastic noise could be attained within two minutes computation time for a single target. The confidence to properly cover both of two targets was 90% for two synchronously moving targets, but decreased by 7% if the targets moved independently. For two partially covered organs at risk the confidence of at least one organ below the mean dose threshold was 40% for synchronous motion, 36% for uncorrelated motion, but only 20% for either of the organs separately. Two abutting dose distributions ensuring 91% confidence of proper target dose for correlated motions led to 28% lower confidence for uncorrelated motions as relative displacements between the doses resulted in cold spots near the target. Conclusions: Probabilistic plan evaluation can efficiently be performed for complicated treatment planning situations, thus providing important plan quality information unavailable in conventional PTV based evaluations.

  10. A comparison of forward planning and optimised inverse planning

    International Nuclear Information System (INIS)

    Oldham, Mark; Neal, Anthony; Webb, Steve

    1995-01-01

    A radiotherapy treatment plan optimisation algorithm has been applied to 48 prostate plans and the results compared with those of an experienced human planner. Twelve patients were used in the study, and a 3, 4, 6 and 8 field plan (with standard coplanar beam angles for each plan type) were optimised by both the human planner and the optimisation algorithm. The human planner 'optimised' the plan by conventional forward planning techniques. The optimisation algorithm was based on fast-simulated-annealing. 'Importance factors' assigned to different regions of the patient provide a method for controlling the algorithm, and it was found that the same values gave good results for almost all plans. The plans were compared on the basis of dose statistics and normal-tissue-complication-probability (NTCP) and tumour-control-probability (TCP). The results show that the optimisation algorithm yielded results that were at least as good as the human planner for all plan types, and on the whole slightly better. A study of the beam-weights chosen by the optimisation algorithm and the planner will be presented. The optimisation algorithm showed greater variation, in response to individual patient geometry. For simple (e.g. 3 field) plans it was found to consistently achieve slightly higher TCP and lower NTCP values. For more complicated (e.g. 8 fields) plans the optimisation also achieved slightly better results with generally less numbers of beams. The optimisation time was always ≤5 minutes; a factor of up to 20 times faster than the human planner

  11. Don't Plan for the Unexpected: Planning Based on Plausibility Models

    DEFF Research Database (Denmark)

    Andersen, Mikkel Birkegaard; Bolander, Thomas; Jensen, Martin Holm

    2015-01-01

    is not computationally feasible. Weak epistemic planning is not satisfactory either, as there is no way to qualify which of two weak plans is more likely to lead to the goal. This seriously limits the practical uses of weak planning, as the planning agent might for instance always choose a plan that relies...... that the agent achieves this goal. Conversely, a weak plan promises only the possibility of leading to the goal. In real-life planning scenarios where the planning agent is faced with a high degree of uncertainty and an almost endless number of possible exogenous events, strong epistemic planning...

  12. Quality Assurance Project Plan for Facility Effluent Monitoring Plan activities

    International Nuclear Information System (INIS)

    Frazier, T.P.

    1994-01-01

    This Quality Assurance Project Plan addresses the quality assurance requirements for the activities associated with the Facility Effluent Monitoring Plans, which are part of the overall Hanford Site Environmental Protection Plan. This plan specifically applies to the sampling and analysis activities and continuous monitoring performed for all Facility Effluent Monitoring Plan activities conducted by Westinghouse Hanford Company. It is generic in approach and will be implemented in conjunction with the specific requirements of the individual Facility Effluent Monitoring Plans

  13. Cost-effectiveness of a cardiovascular disease primary prevention programme in a primary health care setting. Results of the Polish part of the EUROACTION project.

    Science.gov (United States)

    Sović, Nevena; Pająk, Andrzej; Jankowski, Piotr; Duenas, Alejandra; Kawecka-Jaszcz, Kalina; Wolfshaut-Wolak, Renata; Stepaniak, Urszula; Kawalec, Paweł

    2013-01-01

    Well designed cardiovascular disease (CVD) prevention programmes appear to be generally applicable and effective in reducing exposure to risk factors and the incidence of disease. However, introducing them broadly into clinical practice would have a significant impact on the healthcare budget, and requires careful consideration. The purpose of this health economic analysis was to assess the potential cost-effectiveness of the model nurse-led, comprehensive CVD primary prevention programme which was prepared and introduced in the EUROACTION project, in high-risk patients in Poland. A Markov model was developed to assess the long-term costs of preventive intervention. The health states modelled were: event-free (all patients at the beginning of observation), stable angina first year, acute myocardial infarction, stable angina subsequent year, myocardial infarction subsequent year, CVD death, and other causes of death. Health benefits from the reduction in risk factors were estimated based on Framingham risk function assuming the probability of defined health states according to British registers. The time horizon of the analysis was ten years, and one Markov cycle length was one year. The analysis was prepared from the healthcare payer's perspective. A willingness to pay threshold of three gross domestic product (GDP) per capita / quality-adjusted life years (QALY) was used. Univariate sensitivity analysis was conducted. Results were presented as an incremental cost-effectiveness ratio (ICER) expressed as an incremental cost per QALY. In Poland, EUROACTION intervention resulted mainly in reductions in the prevalence of smoking (by 14%) and high blood pressure (by 7%). Intervention on other risk factors, including blood lipids, was found to be less effective. Estimated ICERs were 19,524 PLN for men and 82,262 PLN for women. The programme was even more cost-effective in smokers i.e. estimated ICERs were 12,377 PLN in men and 53,471 PLN in women. The results were most

  14. La versión débil de la hipótesis del pensamiento en lenguaje natural

    Directory of Open Access Journals (Sweden)

    Liza Skidelsky

    2009-11-01

    Full Text Available Normal 0 21 false false false ES X-NONE X-NONE MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabla normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} Entre los filósofos que consideran que pensamos utilizando representaciones simbólicas, P. Carruthers ha defendido, versus la hipótesis del ‘lenguaje del pensamiento' (LDP, una versión débil de la hipótesis del ‘pensamiento en lenguaje natural' (PLN. En este trabajo, me ocuparé, en primer lugar, de mostrar las razones por las cuales Carruthers, en su defensa de la hipótesis débil del PLN, siembra cierta confusión en la polémica entre el LDP y PLN. En segundo lugar, intentaré esbozar una salida de esta confusión, ofreciendo y evaluando dos opciones posibles, i.e. la estrategia trascendental y la de la inferencia a la mejor explicación revisada, para quien desee sostener una versión débil del PLN que no desvirtúe la polémica.Among the philosophers who believe that we think with symbolic representations, P. Carruthers has defended -against the ‘language of thought' hypothesis (LOT- a weak version of the ‘thinking in natural language' hypothesis (TNL. In this paper, I will firstly state the reasons why I think that Carruthers throws the LOT-TNL debate into some confusion. Secondly, I will try to outline a way out of this confusion, offering and evaluating two possible options -i.e., the

  15. Forward planning

    International Nuclear Information System (INIS)

    Fontenla, D.P.

    2008-01-01

    By definition, forward planning is a process where input consists of conditions on beam configurations and parameters and output consists of dose distributions on target and critical structures, in contrast to inverse planning, where the opposite is true. For forward planning IMRT, criteria are as follows: (i) Plans created as an extension of standard 3D conformational planning; (ii) No significant increase in the complexity of the treatment planning or treatment delivery process; (3) Treatment verification using standard QA procedures; and process consists of the following steps: (i) Create a standard 3D conformational treatment plan; (ii) Copy one of the existing beams; (iii) Create control points: design new beam segments, blocking high dose areas; (iv) Repeat for all beams; (v) Re-compute dose; and (vi) Adjust control points weights to achieve desired dose distribution. A detailed exposition, with many clinical examples, is given for the breast, lung, and brain (P.A.)

  16. Who plans for health improvement? SEA, HIA and the separation of spatial planning and health planning

    International Nuclear Information System (INIS)

    Bond, Alan; Cave, Ben; Ballantyne, Rob

    2013-01-01

    This study examines whether there is active planning for health improvement in the English spatial planning system and how this varies across two regions using a combination of telephone surveys and focus group interviews in 2005 and 2010. The spatial planning profession was found to be ill-equipped to consider the health and well-being implications of its actions, whilst health professionals are rarely engaged and have limited understanding and aspirations when it comes to influencing spatial planning. Strategic Environmental Assessment was not considered to be successful in integrating health into spatial plans, given it was the responsibility of planners lacking the capacity to do so. For their part, health professionals have insufficient knowledge and understanding of planning and how to engage with it to be able to plan for health gains rather than simply respond to health impacts. HIA practice is patchy and generally undertaken by health professionals outside the statutory planning framework. Thus, whilst appropriate assessment tools exist, they currently lack a coherent context within which they can function effectively and the implementation of the Kiev protocol requiring the engagement of health professionals in SEA is not to likely improve the consideration of health in planning while there continues to be separation of functions between professions and lack of understanding of the other profession. -- Highlights: ► Health professionals have limited aspirations for health improvement through the planning system. ► Spatial planners are ill-equipped to understand the health and well-being implications of their activities. ► SEA and HIA currently do not embed health consideration in planning decisions. ► The separation of health and planning functions is problematic for the effective conduct of SEA and/or HIA

  17. Who plans for health improvement? SEA, HIA and the separation of spatial planning and health planning

    Energy Technology Data Exchange (ETDEWEB)

    Bond, Alan, E-mail: alan.bond@uea.ac.uk [InteREAM (Interdisciplinary Research in Environmental Assessment and Management), School of Environmental Sciences, University of East Anglia, Norwich, NR4 7TJ (United Kingdom); Cave, Ben, E-mail: ben.cave@bcahealth.co.uk [Ben Cave Associates Ltd., Leeds (United Kingdom); Ballantyne, Rob, E-mail: robdballantyne@gmail.com [Planning and Health Consultant, Oxfordshire (United Kingdom)

    2013-09-15

    This study examines whether there is active planning for health improvement in the English spatial planning system and how this varies across two regions using a combination of telephone surveys and focus group interviews in 2005 and 2010. The spatial planning profession was found to be ill-equipped to consider the health and well-being implications of its actions, whilst health professionals are rarely engaged and have limited understanding and aspirations when it comes to influencing spatial planning. Strategic Environmental Assessment was not considered to be successful in integrating health into spatial plans, given it was the responsibility of planners lacking the capacity to do so. For their part, health professionals have insufficient knowledge and understanding of planning and how to engage with it to be able to plan for health gains rather than simply respond to health impacts. HIA practice is patchy and generally undertaken by health professionals outside the statutory planning framework. Thus, whilst appropriate assessment tools exist, they currently lack a coherent context within which they can function effectively and the implementation of the Kiev protocol requiring the engagement of health professionals in SEA is not to likely improve the consideration of health in planning while there continues to be separation of functions between professions and lack of understanding of the other profession. -- Highlights: ► Health professionals have limited aspirations for health improvement through the planning system. ► Spatial planners are ill-equipped to understand the health and well-being implications of their activities. ► SEA and HIA currently do not embed health consideration in planning decisions. ► The separation of health and planning functions is problematic for the effective conduct of SEA and/or HIA.

  18. Inspection planning

    International Nuclear Information System (INIS)

    Korosec, D.; Levstek, M.F.

    2001-01-01

    Slovenian Nuclear Safety Administration (SNSA) division of nuclear and radiological safety inspection has developed systematic approach to their inspections. To be efficient in their efforts regarding regular and other types of inspections, in past years, the inspection plan has been developed. It is yearly based and organized on a such systematic way, that all areas of nuclear safety important activities of the licensee are covered. The inspection plan assures appropriate preparation for conducting the inspections, allows the overview of the progress regarding the areas to be covered during the year. Depending on the licensee activities and nature of facility (nuclear power plant, research reactor, radioactive waste storage, others), the plan has different levels of intensity of inspections and also their frequency. One of the basic approaches of the plan is to cover all nuclear and radiological important activities on such way, that all regulatory requests are fulfilled. In addition, the inspection plan is a good tool to improve inspection effectiveness based on previous experience and allows to have the oversight of the current status of fulfillment of planned inspections. Future improvement of the plan is necessary in the light of newest achievements on this field in the nuclear world, that means, new types of inspections are planned and will be incorporated into plan in next year.(author)

  19. Peer-Learning Networks in Social Work Doctoral Education: An Interdisciplinary Model

    Science.gov (United States)

    Miller, J. Jay; Duron, Jacquelynn F.; Bosk, Emily Adlin; Finno-Velasquez, Megan; Abner, Kristin S.

    2016-01-01

    Peer-learning networks (PLN) can be valuable tools for doctoral students. Participation in these networks can aid in the completion of the dissertation, lead to increased scholarship productivity, and assist in student retention. Yet, despite the promise of PLNs, few studies have documented their effect on social work doctoral education. This…

  20. Systemic Planning: Dealing with Complexity by a Wider Approach to Planning

    DEFF Research Database (Denmark)

    Leleur, Steen

    2005-01-01

    and methodology that can be helpful for planning under circumstances characterised by complexity and uncertainty. It is argued that compared to conventional, planning – referred to as systematic planning - there is a need for a wider, more systemic approach to planning that is better suited to current real......On the basis of a new book Systemic Planning this paper addresses systems thinking and complexity in a context of planning. Specifically, renewal of planning thinking on this background is set out as so-called systemic planning (SP). The principal concern of SP is to provide principles...

  1. What contributes to action plan enactment? Examining characteristics of physical activity plans.

    Science.gov (United States)

    Fleig, Lena; Gardner, Benjamin; Keller, Jan; Lippke, Sonia; Pomp, Sarah; Wiedemann, Amelie U

    2017-11-01

    Individuals with chronic conditions can benefit from formulating action plans to engage in regular physical activity. However, the content and the successful translation of plans into action, so-called plan enactment, are rarely adequately evaluated. The aim of this study was to describe the content of user-specified plans and to examine whether participants were more likely to enact their plans if these plans were highly specific, viable, and instrumental. The study presents secondary analyses from a larger behavioural intervention in cardiac and orthopaedic rehabilitation. The content of 619 action plans from 229 participants was evaluated by two independent raters (i.e., qualitative analyses and ratings of specificity) and by participants themselves (i.e., instrumentality and viability). Plan enactment was also measured via self-reports. Multilevel analyses examined the relationship between these plan characteristics and subsequent plan enactment, and between plan enactment and aggregated physical activity. Participants preferred to plan leisure-time physical activities anchored around time-based cues. Specificity of occasion cues (i.e., when to act) and highly instrumental plans were positively associated with plan enactment. Interestingly, individuals who planned less specific behavioural responses (i.e., what to do) were more likely to enact their plans. Plan enactment was positively associated with aggregated behaviour. Interventions should not only emphasize the importance of planning, but also the benefits of formulating specific contextual cues. Planning of the behavioural response seems to require less precision. Allowing for some flexibility in executing the anticipated target behaviour seems to aid successful plan enactment. Statement of Contribution What is already known on this subject? Action planning interventions are efficacious in promoting health behaviour. Characteristics of plan content (i.e., specificity) matter for unconditional behaviour

  2. Radiation Planning Assistant - A Streamlined, Fully Automated Radiotherapy Treatment Planning System

    Science.gov (United States)

    Court, Laurence E.; Kisling, Kelly; McCarroll, Rachel; Zhang, Lifei; Yang, Jinzhong; Simonds, Hannah; du Toit, Monique; Trauernicht, Chris; Burger, Hester; Parkes, Jeannette; Mejia, Mike; Bojador, Maureen; Balter, Peter; Branco, Daniela; Steinmann, Angela; Baltz, Garrett; Gay, Skylar; Anderson, Brian; Cardenas, Carlos; Jhingran, Anuja; Shaitelman, Simona; Bogler, Oliver; Schmeller, Kathleen; Followill, David; Howell, Rebecca; Nelson, Christopher; Peterson, Christine; Beadle, Beth

    2018-01-01

    The Radiation Planning Assistant (RPA) is a system developed for the fully automated creation of radiotherapy treatment plans, including volume-modulated arc therapy (VMAT) plans for patients with head/neck cancer and 4-field box plans for patients with cervical cancer. It is a combination of specially developed in-house software that uses an application programming interface to communicate with a commercial radiotherapy treatment planning system. It also interfaces with a commercial secondary dose verification software. The necessary inputs to the system are a Treatment Plan Order, approved by the radiation oncologist, and a simulation computed tomography (CT) image, approved by the radiographer. The RPA then generates a complete radiotherapy treatment plan. For the cervical cancer treatment plans, no additional user intervention is necessary until the plan is complete. For head/neck treatment plans, after the normal tissue and some of the target structures are automatically delineated on the CT image, the radiation oncologist must review the contours, making edits if necessary. They also delineate the gross tumor volume. The RPA then completes the treatment planning process, creating a VMAT plan. Finally, the completed plan must be reviewed by qualified clinical staff. PMID:29708544

  3. Comparison of CT based-CTV plan and CT based-ICRU38 plan in brachytherapy planning of uterine cervix cancer

    International Nuclear Information System (INIS)

    Shim, Jin Sup; Jo, Jung Kun; Si, Chang Keun; Lee, Ki Ho; Lee, Du Hyun; Choi, Kye Suk

    2004-01-01

    Although Improve of CT, MRI Radio-diagnosis and Radiation Therapy Planing, but we still use ICRU38 Planning system(2D film-based) broadly. 3-Dimensional ICR plan(CT image based) is not only offer tumor and normal tissue dose but also support DVH information. On this study, we plan irradiation-goal dose on CTV(CTV plan) and irradiation-goal dose on ICRU 38 point(ICRU38 plan) by use CT image. And compare with tumor-dose, rectal-dose, bladder-dose on both planning, and analysis DVH Sample 11 patients who treated by Ir-192 HDR. After 40 Gy external radiation therapy, ICR plan established. All the patients carry out CT-image scanned by CT-simulator. And we use PLATO(Nucletron) v.14.2 planing system. We draw CTV, rectum, bladder on the CT image. And establish plan irradiation- dose on CTV(CTV plan) and irradiation- dose on A-point(ICRU38 plan) CTV volume(average±SD) is 21.8±26.6 cm 3 , rectum volume(average±SD) is 60.9±25.0 cm 3 , bladder volume(average±SD) is 116.1±40.1cm 3 sampled 11 patients. The volume including 100% dose is 126.7±18.9 cm 3 on ICRU plan and 98.2±74.5 cm 3 on CTV plan. On ICRU planning, the other one's 22.0 cm 3 CTV volume who residual tumor size excess 4cm is not including 100% isodose. 8 patient's 12.9±5.9 cm 3 tumor volume who residual tumor size below 4 cm irradiated 100% dose. Bladder dose(recommended by ICRU 38) is 90.1±21.3 % on ICRU plan, 68.7±26.6% on CTV plan, and rectal dose is 86.4±18.3%, 76.9±15.6%. Bladder and Rectum maximum dose is 137.2±5.9%, 101.1±41.8% on ICRU plan, 107.6±47.9%, 86.9±30.8% on CTV plan. Therefore CTV plan more less normal issue-irradiated dose than ICRU plan. But one patient case who residual tumor size excess 4 cm, Normal tissue dose more higher than critical dose remarkably on CTV plan. 80% over-Irradiated rectal dose(V80rec) is 1.8±2.4 cm 3 on ICRU plan, 0.7±1.0 cm 3 on CTV plan. 80% over-Irradiated bladder dose(V80bla) is 12.2%±8.9 cm 3 on ICRU plan, 3.5±4.1 cm 3 on CTV plan. Likewise, CTV

  4. Land use planning in Safer Transportation Network Planning : safety principles, planning framework, and library information.

    NARCIS (Netherlands)

    Hummel, T.

    2001-01-01

    This report is one in a series of publications, used in the development of the network planning tool ‘Safer Transportation Network Planning’ (Safer-TNP). The publications were used to guide the development of planning structures, diagnostic tools, planning recommendations, and research information

  5. To plan or not to plan: Does planning for production remove facilitation from associative priming?

    Science.gov (United States)

    Jongman, Suzanne R; Meyer, Antje S

    2017-11-01

    Theories of conversation propose that in order to have smooth transitions from one turn to the next, speakers already plan their response while listening to their interlocutor. Moreover, it has been argued that speakers align their linguistic representations (i.e. prime each other), thereby reducing the processing costs associated with concurrent listening and speaking. In two experiments, we assessed how identity and associative priming from spoken words onto picture naming were affected by a concurrent speech planning task. In a baseline (no name) condition, participants heard prime words that were identical, associatively related, or unrelated to target pictures presented two seconds after prime onset. Each prime was accompanied by a non-target picture and followed by its recorded name. The participant did not name the non-target picture. In the plan condition, the participants first named the non-target picture, instead of listening to the recording, and then the target. In Experiment 1, where the plan- and no-plan conditions were tested between participants, priming effects of equal strength were found in the plan and no-plan condition. In Experiment 2, where the two conditions were tested within participants, the identity priming effect was maintained, but the associative priming effect was only seen in the no-plan but not in the plan condition. In this experiment, participant had to decide at the onset of each trial whether or not to name the non-target picture, rendering the task more complex than in Experiment 1. These decision processes may have interfered with the processing of the primes. Thus, associative priming can take place during speech planning, but only if the cognitive load is not too high. Copyright © 2017 Elsevier B.V. All rights reserved.

  6. Teaching Treatment Planning.

    Science.gov (United States)

    Seligman, Linda

    1993-01-01

    Describes approach to teaching treatment planning that author has used successfully in both seminars and graduate courses. Clarifies nature and importance of systematic treatment planning, then describes context in which treatment planning seems more effectively taught, and concludes with step-by-step plan for teaching treatment planning.…

  7. Marine Spatial Planning: Norway´s management plans

    OpenAIRE

    Hoel, Alf Håkon; Olsen, Erik

    2010-01-01

    Since the adoption of a government white paper on ocean governance in 2001, Norway has worked on the development and implementation of marine spatial planning in the format of regional management plans. Management plans for the Barents Sea and the oceans off northern Norway and the Norwegian Sea were adopted in 2006 and 2009, respect...

  8. Climate plan 2004; Plan climat 2004

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    The Climate Plan is an action plan drawn up by the French Government to respond to the climate change challenge, first by 2010 (complying with the Kyoto Protocol target), and, secondly, beyond this date. Projections for France show that national emissions could be 10% higher than the Kyoto target in 2010 if no measures are taken. This is particularly due to increasing emissions in the sectors affecting daily life (residential-tertiary sectors, transport, etc.). For this reason, the Climate Plan contains measures affecting all sectors of the economy and the daily life of all French citizens with a view to economizing the equivalent of 54 million tonnes of CO{sub 2} each year by the year 2010, which will help to reverse the trend significantly. Beyond 2010, the Climate Plan sets out a strategy for technological research which will enable France to meet a target of reducing greenhouse gas emissions four or fivefold by 2050. (author)

  9. 76 FR 67105 - Cash Balance Plans; Benefit Determinations and Plan Valuations for Statutory Hybrid Plans...

    Science.gov (United States)

    2011-10-31

    ... annuity conversion rate. Under PBGC's operating policy on cash balance plans (established pre-PPA 2006... pension equity plan that provides for the use of deferred annuity conversion factors (or an interest rate... annuity conversion plan that uses a variable interest rate to determine the amount of a benefit, PBGC...

  10. DEFINED CONTRIBUTION PLANS, DEFINED BENEFIT PLANS, AND THE ACCUMULATION OF RETIREMENT WEALTH

    Science.gov (United States)

    Poterba, James; Rauh, Joshua; Venti, Steven; Wise, David

    2010-01-01

    The private pension structure in the United States, once dominated by defined benefit (DB) plans, is currently divided between defined contribution (DC) and DB plans. Wealth accumulation in DC plans depends on the participant's contribution behavior and on financial market returns, while accumulation in DB plans is sensitive to a participant's labor market experience and to plan parameters. This paper simulates the distribution of retirement wealth under representative DB and DC plans. It uses data from the Health and Retirement Study (HRS) to explore how asset returns, earnings histories, and retirement plan characteristics contribute to the variation in retirement wealth outcomes. We simulate DC plan accumulation by randomly assigning individuals a share of wages that they and their employer contribute to the plan. We consider several possible asset allocation strategies, with asset returns drawn from the historical return distribution. Our DB plan simulations draw earnings histories from the HRS, and randomly assign each individual a pension plan drawn from a sample of large private and public defined benefit plans. The simulations yield distributions of both DC and DB wealth at retirement. Average retirement wealth accruals under current DC plans exceed average accruals under private sector DB plans, although DC plans are also more likely to generate very low retirement wealth outcomes. The comparison of current DC plans with more generous public sector DB plans is less definitive, because public sector DB plans are more generous on average than their private sector counterparts. PMID:21057597

  11. Automated IMRT planning with regional optimization using planning scripts.

    Science.gov (United States)

    Xhaferllari, Ilma; Wong, Eugene; Bzdusek, Karl; Lock, Michael; Chen, Jeff

    2013-01-07

    Intensity-modulated radiation therapy (IMRT) has become a standard technique in radiation therapy for treating different types of cancers. Various class solutions have been developed for simple cases (e.g., localized prostate, whole breast) to generate IMRT plans efficiently. However, for more complex cases (e.g., head and neck, pelvic nodes), it can be time-consuming for a planner to generate optimized IMRT plans. To generate optimal plans in these more complex cases which generally have multiple target volumes and organs at risk, it is often required to have additional IMRT optimization structures such as dose limiting ring structures, adjust beam geometry, select inverse planning objectives and associated weights, and additional IMRT objectives to reduce cold and hot spots in the dose distribution. These parameters are generally manually adjusted with a repeated trial and error approach during the optimization process. To improve IMRT planning efficiency in these more complex cases, an iterative method that incorporates some of these adjustment processes automatically in a planning script is designed, implemented, and validated. In particular, regional optimization has been implemented in an iterative way to reduce various hot or cold spots during the optimization process that begins with defining and automatic segmentation of hot and cold spots, introducing new objectives and their relative weights into inverse planning, and turn this into an iterative process with termination criteria. The method has been applied to three clinical sites: prostate with pelvic nodes, head and neck, and anal canal cancers, and has shown to reduce IMRT planning time significantly for clinical applications with improved plan quality. The IMRT planning scripts have been used for more than 500 clinical cases.

  12. Planning for seven generations: Energy planning of American Indian tribes

    International Nuclear Information System (INIS)

    Brookshire, Daniel; Kaza, Nikhil

    2013-01-01

    The prevalence of energy resources on American Indian lands, the links between energy management and tribal sovereignty, and recent federal government incentives make tribal energy planning an interesting case study for community energy planning in the US. This paper studies the strategic energy planning efforts, energy resource development, and energy efficiency policies established by tribes within the continental US. The paper analyzes the results of a survey of various tribes′ energy resource development and planning efforts and supplements the responses with publicly available information on resources, economics, and demographics. We find that incentives and advisory services from the federal government are key to developing the capacity of the tribes to pursue energy planning and energy resource development. These incentives largely avoid the misdeeds of past federal policy by promoting tribal control over energy planning and energy resource development efforts. Tribes with formal energy plans or visions are more likely to develop energy resources than tribes without them and are engaged in a more comprehensive and sustainable approach to energy resource development and energy efficiency. - Highlights: • American Indian tribal energy planning is an understudied topic. • Tribal energy planning is interconnected with tribal sovereignty and sustainability. • We report the results of a survey of energy planning and development efforts. • Federal Government assistance is critical to the efforts of the tribes. • Tribes with energy plans take a more comprehensive approach to energy resource development

  13. Planning principles as integral tool of financial planning implementation at enterprise

    Directory of Open Access Journals (Sweden)

    A.V. Overchuk

    2016-09-01

    Full Text Available The main problems of using financial planning tools, namely its principles, in order to achieve an effective system of financial planning at the enterprise are considered. Planning is an integral part of management and provides achievement of sustainable enterprise development, that is why, effective financial planning is the necessary means of realization of the main objective of the company – profit maximization. It is determined that the principles of financial planning are the objective category of planning science, which serves as a starting fundamental concept that expresses the cumulative effect of a number of laws. In addition, on the base of the aggregation and analysis of planning principles the system of financial planning principles is specified, providing efficient financial planning and control functions use, achievement of the mission and objectives of the economic entity activity management and ensuring of its profitability. The scientific novelty of the research lies in the specification of financial planning principles defining at the enterprise and their semantic characteristics

  14. LANDSCAPE PLANNING IN UKRAINE: THE FIRST LANDSCAPE-PLANNING PROGRAM

    Directory of Open Access Journals (Sweden)

    Leonid Rudenko

    2013-01-01

    Full Text Available The paper presents the results of the first, in Ukraine; project on landscape planning widely accepted in European countries. Under the project implemented in 2010–2013, a landscape-planning program has been developed for the Cherkassy oblast. This is the first document of this kind in Ukraine. The program is mainly based on the experience of the German and Russian schools of landscape planning and on research and assessment conducted by the authors, which allowed identifying approaches to landscape planning, principles of the national policy, and characteristics and potential of environmentally friendly planning in Ukraine. The paper discusses the main phases of the work on the development of the landscape program for the oblast. It also identifies the main stages and key concepts and principles of landscape planning. The paper presents the results of integrated research on the identification and classification of conflicts in land use and the integral concept of the developmental goals for the oblast. The results can be the foundation for adopting management decisions and development of action plans for the lower hierarchal branches.

  15. Operation planning device

    International Nuclear Information System (INIS)

    Watanabe, Takashi; Odakawa, Naoto; Erikuchi, Makoto; Okada, Masayuki; Koizumi, Atsuhiko.

    1996-01-01

    The device of the present invention provides a device suitable for monitoring a reactor core state and operation replanning in terms of reactor operation. Namely, (1) an operation result difference judging means judges that replanning is necessary when the operation results deviates from the operation planning, (2) an operation replanning rule data base storing means stores a deviation key which shows various kinds of states where the results deviate from the planning and a rule for replanning for returning to the operation planning on every deviating key, (3) an operation replanning means forms a new operation planning in accordance with the rule which is retrieved based on the deviation key, (4) an operation planning optimizing rule data base storing means evaluates the reformed planning and stores it on every evaluation item, (5) an operation planning optimization means correct the operation planning data so as to be optimized when the evaluation of the means (4) is less than a reference value, and (6) an operation planning display means edits adaptable operation planning data and the result of the evaluation and displays them. (I.S.)

  16. 14 CFR 152.105 - Sponsors and planning agencies: Airport planning.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Sponsors and planning agencies: Airport planning. 152.105 Section 152.105 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF....105 Sponsors and planning agencies: Airport planning. (a) To be eligible to apply for a project for...

  17. Planning hierarchy, modeling and sdvanced planning dystems

    OpenAIRE

    Meyr, Herbert Ottmar

    2003-01-01

    Planning hierarchy, modeling and sdvanced planning dystems / B. Fleischmann, H. Meyr. - In: Supply chain management / ed. by A. G. de Kok ... - Amsterdam u.a. : Elsevier, 2003. - (Handbooks in operations research and management science ; 11)

  18. Assessment of PlanIQ Feasibility DVH for head and neck treatment planning.

    Science.gov (United States)

    Fried, David V; Chera, Bhishamjit S; Das, Shiva K

    2017-09-01

    Designing a radiation plan that optimally delivers both target coverage and normal tissue sparing is challenging. There are limited tools to determine what is dosimetrically achievable and frequently the experience of the planner/physician is relied upon to make these determinations. PlanIQ software provides a tool that uses target and organ at risk (OAR) geometry to indicate the difficulty of achieving different points for organ dose-volume histograms (DVH). We hypothesized that PlanIQ Feasibility DVH may aid planners in reducing dose to OARs. Clinically delivered head and neck treatments (clinical plan) were re-planned (re-plan) putting high emphasis on maximally sparing the contralateral parotid gland, contralateral submandibular gland, and larynx while maintaining routine clinical dosimetric objectives. The planner was blinded to the results of the clinically delivered plan as well as the Feasibility DVHs from PlanIQ. The re-plan treatments were designed using 3-arc VMAT in Raystation (RaySearch Laboratories, Sweden). The planner was then given the results from the PlanIQ Feasibility DVH analysis and developed an additional plan incorporating this information using 4-arc VMAT (IQ plan). The DVHs across the three treatment plans were compared with what was deemed "impossible" by PlanIQ's Feasibility DVH (Impossible DVH). The impossible DVH (red) is defined as the DVH generated using the minimal dose that any voxel outside the targets must receive given 100% target coverage. The re-plans performed blinded to PlanIQ Feasibilty DVH achieved superior sparing of aforementioned OARs compared to the clinically delivered plans and resulted in discrepancies from the impossible DVHs by an average of 200-700 cGy. Using the PlanIQ Feasibility DVH led to additionalOAR sparing compared to both the re-plans and clinical plans and reduced the discrepancies from the impossible DVHs to an average of approximately 100 cGy. The dose reduction from clinical to re-plan and re-plan to

  19. Improved Planning Time and Plan Quality Through Multicriteria Optimization for Intensity-Modulated Radiotherapy

    International Nuclear Information System (INIS)

    Craft, David L.; Hong, Theodore S.; Shih, Helen A.; Bortfeld, Thomas R.

    2012-01-01

    Purpose: To test whether multicriteria optimization (MCO) can reduce treatment planning time and improve plan quality in intensity-modulated radiotherapy (IMRT). Methods and Materials: Ten IMRT patients (5 with glioblastoma and 5 with locally advanced pancreatic cancers) were logged during the standard treatment planning procedure currently in use at Massachusetts General Hospital (MGH). Planning durations and other relevant planning information were recorded. In parallel, the patients were planned using an MCO planning system, and similar planning time data were collected. The patients were treated with the standard plan, but each MCO plan was also approved by the physicians. Plans were then blindly reviewed 3 weeks after planning by the treating physician. Results: In all cases, the treatment planning time was vastly shorter for the MCO planning (average MCO treatment planning time was 12 min; average standard planning time was 135 min). The physician involvement time in the planning process increased from an average of 4.8 min for the standard process to 8.6 min for the MCO process. In all cases, the MCO plan was blindly identified as the superior plan. Conclusions: This provides the first concrete evidence that MCO-based planning is superior in terms of both planning efficiency and dose distribution quality compared with the current trial and error–based IMRT planning approach.

  20. Planning Tool for Strategic Evaluation of Facility Plans - 13570

    Energy Technology Data Exchange (ETDEWEB)

    Magoulas, Virginia; Cercy, Michael [Savannah River National Laboratory, Savannah River Site, Aiken, SC 29808 (United States); Hall, Irin [Newport News Shipbuilding, 4101 Washington Ave., Newport News, VA 23607 (United States)

    2013-07-01

    Savannah River National Laboratory (SRNL) has developed a strategic planning tool for the evaluation of the utilization of its unique resources for processing and research and development of nuclear materials. The Planning Tool is a strategic level tool for assessing multiple missions that could be conducted utilizing the SRNL facilities and showcasing the plan. Traditional approaches using standard scheduling tools and laying out a strategy on paper tended to be labor intensive and offered either a limited or cluttered view for visualizing and communicating results. A tool that can assess the process throughput, duration, and utilization of the facility was needed. SRNL teamed with Newport News Shipbuilding (NNS), a division of Huntington Ingalls Industries, to create the next generation Planning Tool. The goal of this collaboration was to create a simulation based tool that allows for quick evaluation of strategies with respect to new or changing missions, and clearly communicates results to the decision makers. This tool has been built upon a mature modeling and simulation software previously developed by NNS. The Planning Tool provides a forum for capturing dependencies, constraints, activity flows, and variable factors. It is also a platform for quickly evaluating multiple mission scenarios, dynamically adding/updating scenarios, generating multiple views for evaluating/communicating results, and understanding where there are areas of risks and opportunities with respect to capacity. The Planning Tool that has been developed is useful in that it presents a clear visual plan for the missions at the Savannah River Site (SRS). It not only assists in communicating the plans to SRS corporate management, but also allows the area stakeholders a visual look at the future plans for SRS. The design of this tool makes it easily deployable to other facility and mission planning endeavors. (authors)

  1. Planning Tool for Strategic Evaluation of Facility Plans - 13570

    International Nuclear Information System (INIS)

    Magoulas, Virginia; Cercy, Michael; Hall, Irin

    2013-01-01

    Savannah River National Laboratory (SRNL) has developed a strategic planning tool for the evaluation of the utilization of its unique resources for processing and research and development of nuclear materials. The Planning Tool is a strategic level tool for assessing multiple missions that could be conducted utilizing the SRNL facilities and showcasing the plan. Traditional approaches using standard scheduling tools and laying out a strategy on paper tended to be labor intensive and offered either a limited or cluttered view for visualizing and communicating results. A tool that can assess the process throughput, duration, and utilization of the facility was needed. SRNL teamed with Newport News Shipbuilding (NNS), a division of Huntington Ingalls Industries, to create the next generation Planning Tool. The goal of this collaboration was to create a simulation based tool that allows for quick evaluation of strategies with respect to new or changing missions, and clearly communicates results to the decision makers. This tool has been built upon a mature modeling and simulation software previously developed by NNS. The Planning Tool provides a forum for capturing dependencies, constraints, activity flows, and variable factors. It is also a platform for quickly evaluating multiple mission scenarios, dynamically adding/updating scenarios, generating multiple views for evaluating/communicating results, and understanding where there are areas of risks and opportunities with respect to capacity. The Planning Tool that has been developed is useful in that it presents a clear visual plan for the missions at the Savannah River Site (SRS). It not only assists in communicating the plans to SRS corporate management, but also allows the area stakeholders a visual look at the future plans for SRS. The design of this tool makes it easily deployable to other facility and mission planning endeavors. (authors)

  2. Strategies for automatic online treatment plan reoptimization using clinical treatment planning system: A planning parameters study

    International Nuclear Information System (INIS)

    Li, Taoran; Wu, Qiuwen; Zhang, You; Vergalasova, Irina; Lee, W. Robert; Yin, Fang-Fang; Wu, Q. Jackie

    2013-01-01

    Purpose: Adaptive radiation therapy for prostate cancer using online reoptimization provides an improved control of interfractional anatomy variations. However, the clinical implementation of online reoptimization is currently limited by the low efficiency of current strategies and the difficulties associated with integration into the current treatment planning system. This study investigates the strategies for performing fast (∼2 min) automatic online reoptimization with a clinical fluence-map-based treatment planning system; and explores the performance with different input parameters settings: dose-volume histogram (DVH) objective settings, starting stage, and iteration number (in the context of real time planning).Methods: Simulated treatments of 10 patients were reoptimized daily for the first week of treatment (5 fractions) using 12 different combinations of optimization strategies. Options for objective settings included guideline-based RTOG objectives, patient-specific objectives based on anatomy on the planning CT, and daily-CBCT anatomy-based objectives adapted from planning CT objectives. Options for starting stages involved starting reoptimization with and without the original plan's fluence map. Options for iteration numbers were 50 and 100. The adapted plans were then analyzed by statistical modeling, and compared both in terms of dosimetry and delivery efficiency.Results: All online reoptimized plans were finished within ∼2 min with excellent coverage and conformity to the daily target. The three input parameters, i.e., DVH objectives, starting stage, and iteration number, contributed to the outcome of optimization nearly independently. Patient-specific objectives generally provided better OAR sparing compared to guideline-based objectives. The benefit in high-dose sparing from incorporating daily anatomy into objective settings was positively correlated with the relative change in OAR volumes from planning CT to daily CBCT. The use of the

  3. Plan's CCCD approach - Country study PLAN-Bangladesh

    NARCIS (Netherlands)

    Uffelen, van G.J.

    2009-01-01

    PLAN Netherlands National Organisation has in coordination with PLAN International Headquarters commissioned an independent formative evaluation study to get systematic insight in the preconditions for appropriate functionality of Child Centred Community Development (CCCD) and to strengthen common

  4. LAND USE PLANNING AND URBAN PLANS: TERRITORIAL BALANCE AS ETHICS

    Directory of Open Access Journals (Sweden)

    Eunice Helena Sguizzardi Abascal

    2012-07-01

    Full Text Available The article suggests a necessary link between urban planning and territorial organization, in order to, through the synergistic relationship between planning tools and their application to planning, implementing a policy of urban and regional management. By linking the development plan for territorial development plans and categories of land use, this methodology helps to streamline operations at multiple scales. The establishment of this network of instruments and shapes the actions of government action against the rapid and intense increase of only economic forces that shape the territory today, suggesting that it is possible to regulate the action of the housing market through planned interventions, valuing the regional balance, social and environmental - ethical by definition. It is suggested that the possible effects predatory natural and built environment can be reversed or prevented by an action articulating these planning instruments are linked to the development and implementation of plans (and projects at multiple scales, approaching from the regional to the local and metropolitan, from regional policies to sectors, that are incidents in the municipal territory. However, the speed and magnitude of the occupation and transformation of soil occur mainly in periods of heating housing, often jeopardize the balance and environmental quality, natural heritage, urban and landscape. It assumes the argument that the overcoming of undesirable environmental effects, triggered by occupation of the ground guided by the real estate sector fast action can be successful with the articulation of levels of planning and intervention. It is proposed that the complexity of contemporary urban and metropolitan requires the articulation of different scales through the use of innovative urban instruments. By articulating these different scales, at the municipal and other levels supra, contributes to, through a network plan to overcome the undesirable dichotomy

  5. Development Plans and Life Plans: Knowledge Sharing?

    Directory of Open Access Journals (Sweden)

    Juan José Vieco Albarracín

    2010-02-01

    Full Text Available This article explores the possibilities of establishing knowledge sharing between governmental development plans and the “life plans” (planes de vida made by indigenous organizations, in particular the life plan of the Asociación de Autoridades Indígenas del Resguardo Tikuna, Cocama, Yagua (Aticoya, municipality of Puerto Nariño, Amazonas, Colombia. Colombia’s Constitution of 1991 created the ETI (Entidad Territorial Indígena,“indigenous territorial entity” as a territorial unit, just like municipalities, departments, and districts. This means that indigenous reservations (or “reserves” or “preserves” and associations should manage public funds, for which they must design a life plan. This inclusion and recognition of indigenous peoples entails that those life plans should articulate with the municipal, departmental, and national development plans. The article illustrates this situation by comparing two welfare programs –Resa (Red de Seguridad Alimentaria “Food Security Network” and Familias Guardabosques (“Forest Ranger Families”– and two income-generating productive and service (tourism projects carried out by Aticoya and the local indigenous councils of communities on the Amazon and Loretoyacu Rivers.

  6. Inverse planning and class solutions for brachytherapy treatment planning

    International Nuclear Information System (INIS)

    Trnkova, P.

    2010-01-01

    Brachytherapy or interventional radiooncology is a method of radiation therapy. It is a method, where a small encapsulated radioactive source is placed near to / in the tumour and therefore delivers high doses directly to the target volume. Organs at risk (OARs) are spared due to the inverse square dose fall-off. In the past years there was a slight stagnation in the development of techniques for brachytherapy treatment. While external beam radiotherapy became more and more sophisticated, in brachytherapy traditional methods have been still used. Recently, 3D imaging was considered also as the modality for brachytherapy and more precise brachytherapy could expand. Nowadays, an image guided brachytherapy is state-of-art in many centres. Integration of imaging methods lead to the dose distribution individually tailored for each patient. Treatment plan optimization is mostly performed manually as an adaptation of a standard loading pattern. Recently, inverse planning approaches have been introduced into brachytherapy. The aim of this doctoral thesis was to analyze inverse planning and to develop concepts how to integrate inverse planning into cervical cancer brachytherapy. First part of the thesis analyzes the Hybrid Inverse treatment Planning and Optimization (HIPO) algorithm and proposes a workflow how to safely work with this algorithm. The problem of inverse planning generally is that only the dose and volume parameters are taken into account and spatial dose distribution is neglected. This fact can lead to unwanted high dose regions in a normal tissue. A unique implementation of HIPO into the treatment planning system using additional features enabled to create treatment plans similar to the plans resulting from manual optimization and to shape the high dose regions inside the CTV. In the second part the HIPO algorithm is compared to the Inverse Planning Simulated Annealing (IPSA) algorithm. IPSA is implemented into the commercial treatment planning system. It

  7. Radioactive waste management plan. Plan 82

    International Nuclear Information System (INIS)

    1982-06-01

    The report is the first account of the nuclear power utilities of Sweden about the plans for the final disposal of the radioactive waste products of the nuclear power. Part 1 describes the general background, the plans for research and development, including the necessary facilities. The time schedule and the calculated costs of the operations are presented. (G.B.)

  8. Comparison of CT based-CTV plan and CT based-ICRU38 plan in brachytherapy planning of uterine cervix cancer

    International Nuclear Information System (INIS)

    Cho, Jung Keun; Han, Tae Jong

    2007-01-01

    Purpose : In spite of recent remarkable improvement of diagnostic imaging modalities such as CT, MRI, and PET and radiation therapy planing systems, ICR plan of uterine cervix cancer, based on recommendation of ICRU38(2D film-based) such as point A, is still used widely. A 3-dimensional ICR plan based on CT image provides Dose-Volume Histogram(DVH) information of the tumor and normal tissue. In this study, we compared tumor-dose, rectal-dose and bladder-dose through an analysis of DVH between CTV plan and ICRU38 plan based on CT image. Method and Material : We analyzed 11 patients with a cervix cancer who received the ICR of Ir-192 HDR. After 40Gy of external beam radiation therapy, ICR plan was established using PLATO(Nucletron) v.14.2 planning system. CT scan was done to all the patients using CT-simulator(Ultra Z, Philips). We contoured CTV, rectum and bladder on the CT image and established CTV plan which delivers the 100% dose to CTV and ICRU plan which delivers the 100% dose to the point A. Result : The volume(average±SD) of CTV, rectum and bladder in all of 11 patients is 21.8±6.6cm 3 , 60.9±25.0cm 3 , 111.6±40.1cm 3 respectively. The volume covered by 100% isodose curve is 126.7±18.9cm 3 in ICRU plan and 98.2±74.5cm 3 in CTV plan(p=0.0001), respectively. In (On) ICRU planning 22.0cm 3 of CTV volume was not covered by 100% isodose curve in one patient whose residual tumor size is greater than 4cm, while more than 100% dose was irradiated unnecessarily to the normal organ of 62.2±4.8cm 3 other than the tumor in the remaining 10 patients with a residual tumor less than 4cm in size. Bladder dose recommended by ICRU 38 was 90.1±21.3% and 68.7±26.6% in ICRU plan and in CTV plan respectively(p=0.001) while rectal dose recommended by ICRU 38 was 86.4±18.3% and 76.9±15.6% in ICRU plan and in CTV plan, respectively(p=0.08). Bladder and rectum maximum dose was 137.2±50.1%, 101.1±41.8% in ICRU plan and 107.6±47.9%, 86.9±30.8% in CTV plan, respectively

  9. Planning integration FY 1996 program plan. Revision 1

    International Nuclear Information System (INIS)

    1995-09-01

    This Multi-Year Program Plan (MAP) Planning Integration Program, Work Breakdown Structure (WBS) Element 1.8.2, is the primary management tool to document the technical, schedule, and cost baseline for work directed by the US Department of Energy (DOE), Richland Operations Office (RL). As an approved document, it establishes an agreement between RL and the performing contractors for the work to be performed. It was prepared by Westinghouse Hanford Company (WHC) and Pacific Northwest Laboratory (PNL). The MYPPs for the Hanford Site programs are to provide a picture from fiscal year (FY) 1996 through FY 2002. At RL Planning and Integration Division (PID) direction, only the FY 1996 Planning Integration Program work scope has been planned and presented in this MAP. Only those known significant activities which occur after FY 1996 are portrayed in this MAP. This is due to the uncertainty of who will be accomplishing what work scope when, following the award of the Management and Integration (M ampersand I) contract

  10. CaMKII effects on inotropic but not lusitropic force frequency responses require phospholamban

    Science.gov (United States)

    Wu, Yiming; Luczak, Elizabeth D; Lee, Eun-Jeong; Hidalgo, Carlos; Yang, Jinying; Gao, Zhan; Li, Jingdong; Wehrens, Xander; Granzier, Henk; Anderson, Mark E

    2014-01-01

    Increasing heart rate enhances cardiac contractility (force frequency relationship, FFR) and accelerates cardiac relaxation (frequency-dependent acceleration of relaxation, FDAR). The positive FFR together with FDAR promotes rapid filling and ejection of blood from the left ventricle (LV) at higher heart rates. Recent studies indicate that the multifunctional Ca2+/calmodulin-dependent protein kinase II (CaMKII) is involved in regulating FFR and FDAR. We used isolated perfused mouse hearts to study the mechanisms of FFR and FDAR in different genetic models, including transgenic myocardial CaMKII inhibition (AC3-I) and phosphalamban knockout (PLN−/−). When the rate was increased from 360 beats/min to 630 beats/min in wild type mouse hearts, the LV developed pressure (LVDP) and the maximum rate of increase in pressure (dP/dt max) increased by 37.6 ± 4.7% and 77.0 ± 8.1%, respectively. However, hearts from AC3-I littermates showed no increase of LVDP and a relatively modest (20.4 ± 3.9 %) increase in dP/dt max. PLN−/− hearts had a negative FFR, and myocardial AC3-I expression did not change the FFR in PLN−/− mice. PLN−/− mouse hearts did not exhibit FDAR, while PLN−/−mice with myocardial AC3-I expression showed further frequency dependent reductions in cardiac relaxation, suggesting CaMKII targets in addition to PLN were critical to myocardial relaxation. We incubated a constitutively active form of CaMKII with chemically-skinned myocardium and found that several myofilament proteins were phosphorylated by CaMKII. However, CaMKII did not affect myofilament calcium sensitivity. Our study shows that CaMKII plays an important role in modulating FFR and FDAR in murine hearts and suggest that PLN is a critical target for CaMKII effects on FFR, while CaMKII effects on FDAR partially require PLN-alternative targets. PMID:22796260

  11. Application of Pharmacokinetics Modelling to Predict Human Exposure of a Cationic Liposomal Subunit Antigen Vaccine System

    Directory of Open Access Journals (Sweden)

    Raj K. S. Badhan

    2017-12-01

    Full Text Available The pharmacokinetics of a liposomal subunit antigen vaccine system composed of the cationic lipid dimethyldioctadecylammonium bromide (DDA and the immunostimulatory agent trehalose 6,6-dibehenate (TDB (8:1 molar ratio combined with the Ag85B-ESAT-6 (H1 antigen were modelled using mouse in-vivo data. Compartment modelling and physiologically based pharmacokinetics (PBPK were used to predict the administration site (muscle and target site (lymph temporal concentration profiles and factors governing these. Initial estimates using compartmental modelling established that quadriceps pharmacokinetics for the liposome demonstrated a long half-life (22.6 days compared to the associated antigen (2.62 days. A mouse minimal-PBPK model was developed and successfully predicted quadriceps liposome and antigen pharmacokinetics. Predictions for the popliteal lymph node (PLN aligned well at earlier time-points. A local sensitivity analysis highlighted that the predicted AUCmuscle was sensitive to the antigen degradation constant kdeg (resulting in a 3-log change more so than the fraction escaping the quadriceps (fe (resulting in a 10-fold change, and the predicted AUCPLN was highly sensitive to fe. A global sensitivity analysis of the antigen in the muscle demonstrated that model predictions were within the 50th percentile for predictions and showed acceptable fits. To further translate in-vitro data previously generated by our group, the mouse minimal-PBPK model was extrapolated to humans and predictions made for antigen pharmacokinetics in muscle and PLN. Global analysis demonstrated that both kdeg and fe had a minimal impact on the resulting simulations in the muscle but a greater impact in the PLN. In summary, this study has predicted the in-vivo fate of DDA:TDB:H1 in humans and demonstrated the roles that formulation degradation and fraction escaping the depot site can play upon the overall depot effect within the site of administration.

  12. Role of regional planning organizations in transportation planning across boundaries

    Science.gov (United States)

    2014-06-11

    The Volpe Center conducted research for the Federal Highway Administration Office of Planning that explores the implications of Regional Planning Organizations (RPO) engaging in transportation planning partnerships and projects of megaregions signifi...

  13. Analysis on factors affecting household customers decision in using electricity at peak time and its correlation towards saving electricity

    Science.gov (United States)

    Pasasa, Linus; Marbun, Parlin; Mariza, Ita

    2015-09-01

    The purpose of this paper is to study and analyse the factors affecting customer decisions in using electricity at peak-load hours (between 17.00 to 22.00 WIB) and their behaviors towards electricity conservation in Indonesian household. The underlying rationale is to influence a reduction in energy consumption by stimulating energy saving behaviors, thereby reducing the impact of energy use on the environment. How is the correlation between the decisions in using electricity during peak load hours with the household customer's behavior towards saving electricity? The primary data is obtained by distributing questionnaires to customers of PT. PLN Jakarta Raya and Tangerang Distribution from Household segment. The data is analysed using the Structural Equation Model (SEM) and AMOS Software. The research is finding that all factors (Personal, Social, PLN Services, Psychological, and Cultural) are positively influence customer decision in using electricity at peak load hours. There is a correlation between the decisions in using electricity during peak load hours with the household customer's behavior towards saving electricity.

  14. Installation design of pump motor control systems for supplied of the RSG-GAS secondary raw water cooling system

    International Nuclear Information System (INIS)

    Kiswanto; Teguh Sulistyo; M-Taufik

    2013-01-01

    It has designed already of an installation of the pump motor control system for supplied of raw water to fulfil the RSG-GAS secondary cooling system. The installation design of this plant is used to supply electrical energy from PLN and 3 phase generator to operate the pump motor embedded multilevel type, capacity, Q = 30 m 3 /h; electric power, PN = 4 kW; voltage, 380V/3-/50Hz, and Y connections that can be operated manually or automatically by using the automatic transfer switch. The results obtained recapitulation total load of 4 kW, the magnitude of the nominal current of 9.5 A; kind of safety and capacity are used NFB 16 A, use of this type of cable to the control panel is PLN NYY 6 mm 2 diameter maximum current capacity of 25 A cable and use the control panel to the pump motor cable type NYY 4 mm 2 diameter maximum current capacity of 20 A. The design of the pump motor control system installation is ready to be implemented. (author)

  15. DOE/NREL supported wind energy activities in Indonesia

    Energy Technology Data Exchange (ETDEWEB)

    Drouilhet, S.

    1997-12-01

    This paper describes three wind energy related projects which are underway in Indonesia. The first is a USAID/Winrock Wind for Island and Nongovernmental Development (WIND) project. The objectives of this project are to train local nongovernmental organizations (NGOs) in the siting, installation, operation, and maintenance of small wind turbines. Then to install up to 20 wind systems to provide electric power for productive end uses while creating micro-enterprises which will generate enough revenue to sustain the wind energy systems. The second project is a joint Community Power Corporation/PLN (Indonesian National Electric Utility) case study of hybrid power systems in village settings. The objective is to evaluate the economic viability of various hybrid power options for several different situations involving wind/photovoltaics/batteries/diesel. The third project is a World Bank/PLN preliminary market assessment for wind/diesel hybrid systems. The objective is to estimate the size of the total potential market for wind/diesel hybrid power systems in Indonesia. The study will examine both wind retrofits to existing diesel mini-grids and new wind-diesel plants in currently unelectrified villages.

  16. Smart City Planning

    DEFF Research Database (Denmark)

    Ekman, Ulrik

    2018-01-01

    This article reflects on the challenges for urban planning posed by the emergence of smart cities in network societies. In particular, it reflects on reductionist tendencies in existing smart city planning. Here the concern is with the implications of prior reductions of complexity which have been...... undertaken by placing primacy in planning on information technology, economical profit, and top-down political government. Rather than pointing urban planning towards a different ordering of these reductions, this article argues in favor of approaches to smart city planning via complexity theory....... Specifically, this article argues in favor of approaching smart city plans holistically as topologies of organized complexity. Here, smart city planning is seen as a theory and practice engaging with a complex adaptive urban system which continuously operates on its potential. The actualizations in the face...

  17. Changed planning for planned and unplanned change

    NARCIS (Netherlands)

    Woerkum, van C.; Aarts, N.; Herzele, Van A.

    2011-01-01

    Change, planned and unplanned, can be the product of events (change by chance), new language (change from societal interaction), and practices (track-bound change), and can involve many different societal actors. To position planning as an activity within this broader context, we present a model

  18. Planned hospital birth versus planned home birth

    DEFF Research Database (Denmark)

    Olsen, O.; Clausen, J.A.

    2012-01-01

    Observational studies of increasingly better quality and in different settings suggest that planned home birth in many places can be as safe as planned hospital birth and with less intervention and fewer complications. This is an update of a Cochrane review first published in 1998....

  19. Planning for strategic change? A participative planning approach for community hospitals.

    Science.gov (United States)

    MacDonald, S K; Beange, J E; Blachford, P C

    1992-01-01

    Strategic planning is becoming to hospitals what business case analysis is to private corporations. In fact, this type of planning is becoming essential for the professional management of Ontario hospitals. The participative strategic planning process at Toronto East General Hospital (TEGH) is an example of how a professionally structured and implemented strategic planning process can be successfully developed and implemented in a community hospital. In this article, the environmental factors driving planning are reviewed and the critical success factors for the development and implementation of a strategic plan are examined in the context of TEGH's experience.

  20. Radiation therapy treatment planning: CT, MR imaging and three-dimensional planning

    International Nuclear Information System (INIS)

    Lichter, A.S.

    1987-01-01

    The accuracy and sophistication of radiation therapy treatment planning have increased rapidly in the last decade. Currently, CT-based treatment planning is standard throughout the country. Care must be taken when CT is used for treatment planning because of clear differences between diagnostic scans and scans intended for therapeutic management. The use of CT in radiation therapy planning is discussed and illustrated. MR imaging adds another dimension to treatment planning. The ability to use MR imaging directly in treatment planning involves an additional complex set of capabilities from a treatment planning system. The ability to unwarp the geometrically distorted MR image is a first step. Three-dimensional dose calculations are important to display the dose on sagittal and acoronal sections. The ability to integrate the MR and CT images into a unified radiographic image is critical. CT and MR images are two-dimensional representations of a three-dimensional problem. Through sophisticated computer graphics techniques, radiation therapists are now able to integrate a three-dimensional image of the patient into the treatment planning process. This allows the use of noncoplanar treatment plans and a detailed analysis of tumor and normal tissue anatomy; it is the first step toward a fully conformational treatment planning system. These concepts are illustrated and future research goals outlined

  1. Preliminary Hanford Waste Vitrification Plan Waste Form Qualification Plan

    International Nuclear Information System (INIS)

    Nelson, J.L.

    1987-09-01

    This Waste Form Qualification Plan describes the waste form qualification activities that will be followed during the design and operation of the Hanford Waste Vitrification Plant to ensure that the vitrified Hanford defense high-level wastes will meet the acceptance requirements of the candidate geologic repositories for nuclear waste. This plan is based on the defense waste processing facility requirements. The content of this plan is based on the assumption that the Hanford Waste Vitrification Plant high-level waste form will be disposed of in one of the geologic repository projects. Proposed legislation currently under consideration by Congress may change or delay the repository site selection process. The impacts of this change will be assessed as details of the new legislation become available. The Plan describes activities, schedules, and programmatic interfaces. The Waste Form Qualification Plan is updated regularly to incorporate Hanford Waste Vitrification Plant-specific waste acceptance requirements and to serve as a controlled baseline plan from which changes in related programs can be incorporated. 10 refs., 5 figs., 5 tabs

  2. From action planning and plan enactment to fruit consumption: moderated mediation effects.

    Science.gov (United States)

    Kasten, Stefanie; van Osch, Liesbeth; Eggers, Sander Matthijs; de Vries, Hein

    2017-10-23

    Sufficient fruit consumption is beneficial for a healthy live. While many Dutch adults intent to eat the recommended amount of fruit, only 5-10% of the population actually adheres to the recommendation. One mechanism that can help to narrow this gap between intention and actual fruit consumption is action planning. However, action planning is only assumed to be effective if plans are enacted. This study assessed which action plans are made and enacted, and further aimed to investigate two main hypotheses: 1. the effect of action planning (at T1) on fruit consumption (at T2) is mediated by plan enactment (at T3); 2. positive intentions (2a), high self-efficacy (2b) and a strong habit to eat fruit (2c) enhance the mediation of plan enactment, whereas a strong habit to eat snacks (2d) hinders the mediation of plan enactment. This study was a self-reported longitudinal online survey study. A total of 428 participants filled in a survey, measuring demographic factors (e.g. gender, age, education level), several socio-cognitive constructs (i.e. attitudes, self-efficacy, habit, action planning, plan enactment), and fruit consumption, at three points in time (baseline, after 1 month, and after 3 months). Mediation and moderated mediation analyses were used to investigate the planning-plan enactment- fruit consumption relationship. Up to 70% of the participants reported to have enacted their T1 action plans at T2. Action planning on fruit consumption was fully mediated by plan enactment (Hypothesis 1). All four proposed moderators (i.e. intention, self-efficacy, habit to consume fruit, and habit to consume snacks) significantly influenced the mediation (Hypotheses 2a-2d). Mediation of plan enactment was only present with high levels of intention, high levels of self-efficacy, strong habits to eat fruit, and weak habits to eat snacks. The study suggests the importance of plan enactment for fruit consumption. Furthermore, it emphasizes the necessity of facilitating factors

  3. Scenario planning.

    Science.gov (United States)

    Enzmann, Dieter R; Beauchamp, Norman J; Norbash, Alexander

    2011-03-01

    In facing future developments in health care, scenario planning offers a complementary approach to traditional strategic planning. Whereas traditional strategic planning typically consists of predicting the future at a single point on a chosen time horizon and mapping the preferred plans to address such a future, scenario planning creates stories about multiple likely potential futures on a given time horizon and maps the preferred plans to address the multiple described potential futures. Each scenario is purposefully different and specifically not a consensus worst-case, average, or best-case forecast; nor is scenario planning a process in probabilistic prediction. Scenario planning focuses on high-impact, uncertain driving forces that in the authors' example affect the field of radiology. Uncertainty is the key concept as these forces are mapped onto axes of uncertainty, the poles of which have opposed effects on radiology. One chosen axis was "market focus," with poles of centralized health care (government control) vs a decentralized private market. Another axis was "radiology's business model," with one pole being a unified, single specialty vs a splintered, disaggregated subspecialty. The third axis was "technology and science," with one pole representing technology enabling to radiology vs technology threatening to radiology. Selected poles of these axes were then combined to create 3 scenarios. One scenario, termed "entrepreneurialism," consisted of a decentralized private market, a disaggregated business model, and threatening technology and science. A second scenario, termed "socialized medicine," had a centralized market focus, a unified specialty business model, and enabling technology and science. A third scenario, termed "freefall," had a centralized market focus, a disaggregated business model, and threatening technology and science. These scenarios provide a range of futures that ultimately allow the identification of defined "signposts" that can

  4. Hanford Site Development Plan

    International Nuclear Information System (INIS)

    Rinne, C.A.; Curry, R.H.; Hagan, J.W.; Seiler, S.W.; Sommer, D.J.; Yancey, E.F.

    1990-01-01

    The Hanford Site Development Plan (Site Development Plan) is intended to guide the short- and long-range development and use of the Hanford Site. All acquisition, development, and permanent facility use at the Hanford Site will conform to the approved plan. The Site Development Plan also serves as the base document for all subsequent studies that involve use of facilities at the Site. This revision is an update of a previous plan. The executive summary presents the highlights of the five major topics covered in the Site Development Plan: general site information, existing conditions, planning analysis, Master Plan, and Five-Year Plan. 56 refs., 67 figs., 31 tabs

  5. Hanford Site Development Plan

    Energy Technology Data Exchange (ETDEWEB)

    Rinne, C.A.; Curry, R.H.; Hagan, J.W.; Seiler, S.W.; Sommer, D.J. (Westinghouse Hanford Co., Richland, WA (USA)); Yancey, E.F. (Pacific Northwest Lab., Richland, WA (USA))

    1990-01-01

    The Hanford Site Development Plan (Site Development Plan) is intended to guide the short- and long-range development and use of the Hanford Site. All acquisition, development, and permanent facility use at the Hanford Site will conform to the approved plan. The Site Development Plan also serves as the base document for all subsequent studies that involve use of facilities at the Site. This revision is an update of a previous plan. The executive summary presents the highlights of the five major topics covered in the Site Development Plan: general site information, existing conditions, planning analysis, Master Plan, and Five-Year Plan. 56 refs., 67 figs., 31 tabs.

  6. Inverse planning for interstitial gynecologic template brachytherapy: truly anatomy-based planning

    International Nuclear Information System (INIS)

    Lessard, Etienne; Hsu, I-Chou; Pouliot, Jean

    2002-01-01

    Purpose: Commercially available optimization schemes generally result in an undesirable dose distribution, because of the particular shapes of tumors extending laterally from the tandem. Dose distribution is therefore manually obtained by adjusting relative dwell time values until an acceptable solution is found. The objective of this work is to present the clinical application of an inverse planning dose optimization tool for the automatic determination of source dwell time values in the treatment of interstitial gynecologic templates. Methods and Materials: In cases where the tumor extends beyond the range of the tandem-ovoid applicator, catheters as well as the tandem are inserted into the paravaginal and parametrial region in an attempt to cover the tumor volume. CT scans of these patients are then used for CT-based dose planning. Dose distribution is obtained manually by varying the relative dwell times until adequate dose coverage is achieved. This manual planning is performed by an experienced physician. In parallel, our in-house inverse planning based on simulated annealing is used to automatically determine which of all possible dwell positions will become active and to calculate the dwell time values needed to fulfill dose constraints applied to the tumor volume and to each organ at risk. To compare the results of these planning methods, dose-volume histograms and isodose distributions were generated for the target and each organ at risk. Results: This procedure has been applied for the dose planning of 12 consecutive interstitial gynecologic templates cases. For all cases, once the anatomy was contoured, the routine of inverse planning based on simulated annealing found the solution to the dose constraints within 1 min of CPU time. In comparison, manual planning took more than 45 min. The inverse planning-generated plans showed improved protection to organs at risk for the same coverage compared to manual planning. Conclusion: This inverse planning tool

  7. The text plan concept: contributions to the writing planning process

    Directory of Open Access Journals (Sweden)

    Ana Lúcia Tinoco Cabral

    2013-12-01

    Full Text Available Students - at different levels, ranging from early grades up to PhD - face problems both on comprehension and text production. This paper focuses on the text plan concept according to the DTA (Discourse Text Analysis approach, i.e., a principle of organization that allows students to put into practice the production intention as well as to arrange text information while producing; being responsible for the text compositional structure (Adam, 2008. The study analyzes the relation between text plan and the writing planning process, in which the first one provides the second with theoretical support. In order to develop such research, the study covers some issues related to the reading skill, analyzes an argumentative text as per its textual plan, and presents some reflections on the writing process, focusing on the relation between textual plan and the writing planning process.

  8. The Modern Management of Urban Planning and the Controlling Planning

    Institute of Scientific and Technical Information of China (English)

    1991-01-01

    <正> Since 1980s,with the further reform of political and economic systems,the urban construc-tion in our country has undergone great changes,greater than ever.Such changes pose a series ofnew problems to urban planning:How should planning be suitable for the development of moderncities?How should planning management coordinate with urban planning?How to carry out ur-ban planning under new situations? etc.The answers to these problems lie in one point:urbanplanning and plann ing management must be restructured.Only when the former is well com-bined with the latter can the above problems be solved satisfactorily.This article provides someviews in this respect.

  9. Penerapan Preventive Maintenance Untuk Meningkatkan Reliability Pada Boiler Feed Pump PLTU Tarahan Unit 3 & 4

    OpenAIRE

    Saputra, Melki

    2015-01-01

    Pemeliharaan dan perawatan merupakan kegiatan untuk menjamin mesin dapat bekerja sebagaimana mestinya. Pemeliharaan dan perawatan menyeluruh untuk meningkatkan produktivitas perusahaan dikenal dengan Preventive Maintenance. pemeliharaan keterlibatan operator melalui kegiatan autonomous maintenance. PT. PLN (Persero) Pembangkitan Sumatera Bagian Selatan Sektor Tarahan merupakan salah satu perusahaan penghasil listrik dan semua mesinnya beroperasi selama 24 jam. Beroperasinya mesin secara c...

  10. 26 CFR 1.401(a)(4)-5 - Plan amendments and plan terminations.

    Science.gov (United States)

    2010-04-01

    ... employer decides to wind up its business. In the process of ceasing operations, but at a time when the plan.... (4) Operational restrictions on certain money purchase pension plans. A money purchase pension plan... 26 Internal Revenue 5 2010-04-01 2010-04-01 false Plan amendments and plan terminations. 1.401(a...

  11. Multiemployer Pension Plans

    Data.gov (United States)

    Pension Benefit Guaranty Corporation — This spreadsheet lists the active multiemployer pensions plans insured by PBGC. Plans are identified by name, employer identification number (EIN) and plan number...

  12. Is pregnancy planning associated with background characteristics and pregnancy-planning behavior?

    DEFF Research Database (Denmark)

    Stern, Jenny; Salih Joelsson, Lana; Tydén, Tanja

    2016-01-01

    household income, to be currently working (≥50%) and to have longer relationships than women with unplanned pregnancies. The level of pregnancy planning was associated with planning behavior, such as information-seeking and intake of folic acid, but without a reduction in alcohol consumption. One......-third of all women took folic acid 1 month prior to conception, 17% used tobacco daily and 11% used alcohol weekly 3 months before conception. Conclusions A majority rated their pregnancy as very or fairly planned, with socio-economic factors as explanatory variables. The level of pregnancy planning should......Introduction Prevalence of planned pregnancies varies between countries but is often measured in a dichotomous manner. The aim of this study was to investigate to what level pregnant women had planned their pregnancies and whether pregnancy planning was associated with background characteristics...

  13. Planning integration FY 1995 Multi-Year Program Plan (MYPP)/Fiscal Year Work Plan (FYWP)

    International Nuclear Information System (INIS)

    1994-09-01

    This Multi-Year Program Plan (MYPP) for the Planning Integration Program, Work Breakdown structure (WBS) Element 1.8.2, is the primary management tool to document the technical, schedule, and cost baseline for work directed by the US Department of Energy (DOE), Richland Operations Office (RL). As an approved document, it establishes a binding agreement between RL and the performing contractors for the work to be performed. It was prepared by the Westinghouse Hanford Company (WHC) and the Pacific Northwest Laboratory (PNL). This MYPP provides a picture from fiscal year 1995 through FY 2001 for the Planning Integration Program. The MYPP provides a window of detailed information for the first three years. It also provides 'execution year' work plans. The MYPP provides summary information for the next four years, documenting the same period as the Activity Data Sheets

  14. Planning integration FY 1995 Multi-Year Program Plan (MYPP)/Fiscal Year Work Plan (FYWP)

    Energy Technology Data Exchange (ETDEWEB)

    1994-09-01

    This Multi-Year Program Plan (MYPP) for the Planning Integration Program, Work Breakdown structure (WBS) Element 1.8.2, is the primary management tool to document the technical, schedule, and cost baseline for work directed by the US Department of Energy (DOE), Richland Operations Office (RL). As an approved document, it establishes a binding agreement between RL and the performing contractors for the work to be performed. It was prepared by the Westinghouse Hanford Company (WHC) and the Pacific Northwest Laboratory (PNL). This MYPP provides a picture from fiscal year 1995 through FY 2001 for the Planning Integration Program. The MYPP provides a window of detailed information for the first three years. It also provides `execution year` work plans. The MYPP provides summary information for the next four years, documenting the same period as the Activity Data Sheets.

  15. Hanford Facility contingency plan

    International Nuclear Information System (INIS)

    Sutton, L.N.; Miskho, A.G.; Brunke, R.C.

    1993-10-01

    The Hanford Facility Contingency Plan, together with each TSD unit-specific contingency plan, meets the WAC 173-303 requirements for a contingency plan. This plan includes descriptions of responses to a nonradiological hazardous materials spill or release at Hanford Facility locations not covered by TSD unit-specific contingency plans or building emergency plans. This plan includes descriptions of responses for spills or releases as a result of transportation activities, movement of materials, packaging, and storage of hazardous materials

  16. Planning Electric Transmission Lines: A Review of Recent Regional Transmission Plans

    Energy Technology Data Exchange (ETDEWEB)

    Eto, Joseph H. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2017-04-13

    The first Quadrennial Energy Review (QER) recommends that the U.S. Department of Energy (DOE) conduct a national review of transmission plans and assess the barriers and incentives to their implementation. DOE tasked Lawrence Berkeley National Laboratory (LBNL) to prepare two reports to support the agency’s response to this recommendation. This report reviews regional transmission plans and regional transmission planning processes that have been directed by Federal Energy Regulatory Commission (FERC) Order Nos. 890 and 1000. We focus on the most recent regional transmission plans (those issued in 2015 and through approximately mid-year 2016) and current regional transmission planning processes. A companion report focuses on non-plan-related factors that affect transmission projects.

  17. Calfornia General Plans

    Data.gov (United States)

    California Natural Resource Agency — We undertook creating the first ever seamless statewide General Plan map for California. All county general plans and many city general plans were integrated into 1...

  18. Public affairs plan

    Energy Technology Data Exchange (ETDEWEB)

    1994-09-01

    The purpose of the Uranium Mill Tailings Remedial Action (UMTRA) Project Public Affairs Plan is to establish goals for the Fiscal Year 1995 UMTRA public affairs program and identify specific activities to be conducted during the year. It also describes the roles of various agencies involved in the conduct of the public affairs program and defines the functions of the Technical Assistance Contractor (TAC) Public Affairs Department. It integrates and replaces the Public Participation Plan (DOE/AL/62350-47D) and Public Information Plan (DOE/AL/623590-71). The plan describes the US Department of Energy`s (DOE) plans to keep stakeholders and other members of the public informed about project policies, plans, and activities, and provide opportunities for stakeholders and interested segments of the public to participate in project decision-making processes. The plan applies to the UMTRA Project Office; the DOE Albuquerque Operations Office, Office of Intergovernmental and External Affairs (OIEA); the UMTRA TAC; the UMTRA Remedial Action Contractor (RAC); and other cooperating agencies.

  19. Public affairs plan

    International Nuclear Information System (INIS)

    1994-09-01

    The purpose of the Uranium Mill Tailings Remedial Action (UMTRA) Project Public Affairs Plan is to establish goals for the Fiscal Year 1995 UMTRA public affairs program and identify specific activities to be conducted during the year. It also describes the roles of various agencies involved in the conduct of the public affairs program and defines the functions of the Technical Assistance Contractor (TAC) Public Affairs Department. It integrates and replaces the Public Participation Plan (DOE/AL/62350-47D) and Public Information Plan (DOE/AL/623590-71). The plan describes the US Department of Energy's (DOE) plans to keep stakeholders and other members of the public informed about project policies, plans, and activities, and provide opportunities for stakeholders and interested segments of the public to participate in project decision-making processes. The plan applies to the UMTRA Project Office; the DOE Albuquerque Operations Office, Office of Intergovernmental and External Affairs (OIEA); the UMTRA TAC; the UMTRA Remedial Action Contractor (RAC); and other cooperating agencies

  20. Feature-based plan adaptation for fast treatment planning in scanned ion beam therapy

    International Nuclear Information System (INIS)

    Chen Wenjing; Gemmel, Alexander; Rietzel, Eike

    2013-01-01

    We propose a plan adaptation method for fast treatment plan generation in scanned ion beam therapy. Analysis of optimized treatment plans with carbon ions indicates that the particle number modulation of consecutive rasterspots in depth shows little variation throughout target volumes with convex shape. Thus, we extract a depth-modulation curve (DMC) from existing reference plans and adapt it for creation of new plans in similar treatment situations. The proposed method is tested with seven CT serials of prostate patients and three digital phantom datasets generated with the MATLAB code. Plans are generated with a treatment planning software developed by GSI using single-field uniform dose optimization for all the CT datasets to serve as reference plans and ‘gold standard’. The adapted plans are generated based on the DMC derived from the reference plans of the same patient (intra-patient), different patient (inter-patient) and phantoms (phantom-patient). They are compared with the reference plans and a re-positioning strategy. Generally, in 1 min on a standard PC, either a physical plan or a biological plan can be generated with the adaptive method provided that the new target contour is available. In all the cases, the V95 values of the adapted plans can achieve 97% for either physical or biological plans. V107 is always 0 indicating no overdosage, and target dose homogeneity is above 0.98 in all cases. The dose received by the organs at risk is comparable to the optimized plans. The plan adaptation method has the potential for on-line adaptation to deal with inter-fractional motion, as well as fast off-line treatment planning, with either the prescribed physical dose or the RBE-weighted dose. (paper)

  1. Logistics planning and logistics planning factors for humanitarian operations

    OpenAIRE

    Sullivan, Donna Marie.

    1995-01-01

    Due to the increasing demand on the military to conduct humanitarian operations, the need for logistics planning factors that are applicable to these operations has arisen. This thesis develops a model for humanitarian operations and employs the model to develop logistics planning factors for material consumption and a computer-assisted planning aid relating to the support of the victim population. U.S. Navy (U.S.N.) author.

  2. Legal consequences of the special development plan 'power plant sites' on regional planning and on guidelines for building plans

    International Nuclear Information System (INIS)

    1978-01-01

    The Special Development Plan 'Power plant sites' was made compulsory by the regulation given by the Land government in Juli 1976. For extending the energy supply system this Special Development Plan intends to provide a sufficient amount of power plant sites suitably located with regard to present and future consumption centres and permitting a cooling by means of river water while safeguarding the interests of water resources policy. The Special Development Plan established in accordance with the articles 25 and 27 of the planning law of the Land lays down that 14 specified areas are to be kept free from utilization purposes which could be opposed to the realization of power plant projects. Thus the securing of these (potential) sites has become an objective of area planning and planning of the Land in the sense of article 5 paragraph 4 of the Federal law on area planning. (orig./HP) [de

  3. Explicit optimization of plan quality measures in intensity-modulated radiation therapy treatment planning.

    Science.gov (United States)

    Engberg, Lovisa; Forsgren, Anders; Eriksson, Kjell; Hårdemark, Björn

    2017-06-01

    To formulate convex planning objectives of treatment plan multicriteria optimization with explicit relationships to the dose-volume histogram (DVH) statistics used in plan quality evaluation. Conventional planning objectives are designed to minimize the violation of DVH statistics thresholds using penalty functions. Although successful in guiding the DVH curve towards these thresholds, conventional planning objectives offer limited control of the individual points on the DVH curve (doses-at-volume) used to evaluate plan quality. In this study, we abandon the usual penalty-function framework and propose planning objectives that more closely relate to DVH statistics. The proposed planning objectives are based on mean-tail-dose, resulting in convex optimization. We also demonstrate how to adapt a standard optimization method to the proposed formulation in order to obtain a substantial reduction in computational cost. We investigated the potential of the proposed planning objectives as tools for optimizing DVH statistics through juxtaposition with the conventional planning objectives on two patient cases. Sets of treatment plans with differently balanced planning objectives were generated using either the proposed or the conventional approach. Dominance in the sense of better distributed doses-at-volume was observed in plans optimized within the proposed framework. The initial computational study indicates that the DVH statistics are better optimized and more efficiently balanced using the proposed planning objectives than using the conventional approach. © 2017 American Association of Physicists in Medicine.

  4. Study on Runoff Debit in the Catchment Area of Waduk Gajah Mungkur Wonogiri

    Directory of Open Access Journals (Sweden)

    Alif Noor Anna

    2004-01-01

    Water resource is one of natural resources, that is very vital. It needed to be used and to be kept throughly. For those purposes need good and directed plan, in which one of the basic component of it plan have to be supported by available a complete hydrological data and it analysis. One of hydrological data analysis is to estimate runoff of catchement area, which can be used for planning the hydrologi construction. This research aim: 1 to calculate the run off discharge by thornwaite Mather Method, monthly, annualy, and the average on the catchment through a sample of Keduang, Temon, Alang, and Wuryantoro areas; 2 to analyze the difference of the run off discharge (at no. 1 by observation resulted from trend analysis. Based on the calculation, it appears, thornwaite-mather method showed that high discharge (moreover limit 0 in dry month. From the research result, it appears, that calculation discharge graphic had lower differentation than observation discharge graphic. From sample of catchment areas that have been investigated, from the highest to the lowest deviation was Wuryantoro catchment area (78,8%, Temon catchment area (47,38%, Alang catchment area (46,45%, and Keduang catchment area (24,98% respectively. The condition like above caused by intervation of man. Not only did he influence vegetatively, but he influenced technically as well. From these conservation, technical conservation (flood and construction and reservoir was the highest influence to run off discharge calculation. The run off discharge that was calculated by thornthwite-Mather Method based on air temperate, rainy, altitude, and water holding capacity only, but groundwater supply didn’t be calculated.

  5. Agent independent task planning

    Science.gov (United States)

    Davis, William S.

    1990-01-01

    Agent-Independent Planning is a technique that allows the construction of activity plans without regard to the agent that will perform them. Once generated, a plan is then validated and translated into instructions for a particular agent, whether a robot, crewmember, or software-based control system. Because Space Station Freedom (SSF) is planned for orbital operations for approximately thirty years, it will almost certainly experience numerous enhancements and upgrades, including upgrades in robotic manipulators. Agent-Independent Planning provides the capability to construct plans for SSF operations, independent of specific robotic systems, by combining techniques of object oriented modeling, nonlinear planning and temporal logic. Since a plan is validated using the physical and functional models of a particular agent, new robotic systems can be developed and integrated with existing operations in a robust manner. This technique also provides the capability to generate plans for crewmembers with varying skill levels, and later apply these same plans to more sophisticated robotic manipulators made available by evolutions in technology.

  6. To Plan or Not to Plan, That Is the Question

    Science.gov (United States)

    Dolph, David A.

    2016-01-01

    Strategic planning is a process utilized by numerous organizations, including K-12 school boards, intent on improvement and reform. A thoughtful strategic planning process can help develop a board's desired future driven by goals and strategies aimed at progress. However, improvement processes such as strategic planning are challenging. In fact,…

  7. Maintenance Business Plans.

    Science.gov (United States)

    Adams, Matt

    2002-01-01

    Discusses maintenance business plans, statements which provide accountability for facilities maintenance organizations' considerable budgets. Discusses the plan's components: statement of plan objectives, macro and detailed description of the facility assets, maintenance function descriptions, description of key performance indicators, milestone…

  8. Drug plan design incentives among Medicare prescription drug plans.

    Science.gov (United States)

    Huskamp, Haiden A; Keating, Nancy L; Dalton, Jesse B; Chernew, Michael E; Newhouse, Joseph P

    2014-07-01

    Medicare Advantage prescription drug plans (MA-PDs) and standalone prescription drug plans (PDPs) face different incentives for plan design resulting from the scope of covered benefits (only outpatient drugs for PDPs versus all drug and nondrug services for Medicare Advantage [MA]/MA-PDs). The objective is to begin to explore how MA-PDs and PDPs may be responding to their different incentives related to benefit design. We compared 2012 PDP and MA-PD average formulary coverage, prior authorization (PA) or step therapy use, and copayment requirements for drugs in 6 classes used commonly among Medicare beneficiaries. We primarily used 2012 Prescription Drug Plan Formulary and Pharmacy Network Files and MA enrollment data. 2011 Truven Health MarketScan claims were used to estimate drug prices and to compute drug market share. Average coverage and PA/step rates, and average copayment requirements, were weighted by plan enrollment and drug market share. MA-PDs are generally more likely to cover and less likely to require PA/step for brand name drugs with generic alternatives than PDPs, and MA-PDs often have lower copayment requirements for these drugs. For brands without generics, we generally found no differences in average rates of coverage or PA/step, but MA-PDs were more likely to cover all brands without generics in a class. We found modest, confirmatory evidence suggesting that PDPs and MA-PDs respond to different incentives for plan design. Future research is needed to understand the factors that influence Medicare drug plan design decisions.

  9. Making Planning Work

    DEFF Research Database (Denmark)

    Eibe Sørensen, Hans

    2018-01-01

    Planning for a growth opportunity's success remains a challenge. Under which conditions does planning work, then? This exploratory study investigates the business development tasks and processes that span a growth opportunity's planning phase and its implementation phase and their unique performa...

  10. The ground based plan

    International Nuclear Information System (INIS)

    1989-01-01

    The paper presents a report of ''The Ground Based Plan'' of the United Kingdom Science and Engineering Research Council. The ground based plan is a plan for research in astronomy and planetary science by ground based techniques. The contents of the report contains a description of:- the scientific objectives and technical requirements (the basis for the Plan), the present organisation and funding for the ground based programme, the Plan, the main scientific features and the further objectives of the Plan. (U.K.)

  11. The Trade-Off between Planning Objectives and Planning Success

    Directory of Open Access Journals (Sweden)

    Laval Valerian

    2016-12-01

    Full Text Available The aim of this paper it to analyse, why companies face difficulties in implementing modern planning concepts. For this the paper will discuss and define the terminology and goals of modern planning. Based on this, the article analyses how strategy orientation influences the willingness of companies to move from traditional budgeting to modern budgeting concepts. It will be outlined, why especially companies pursuing a cost leadership strategy are still reluctant to open themselves for modern budgeting concepts. The contribution of this paper is to analyse the influence of the strategy orientation on the readiness of organizations. Also it will be illustrated, how the overall value added of the corporate planning can be improved by prioritizing the most appropriate planning objectives.

  12. Strategic Planning and the Long-term R&D Plan

    International Nuclear Information System (INIS)

    Cooley, J.

    2015-01-01

    The Department of Safeguards of the International Atomic Energy Agency implements a structured strategic planning process to ensure that safeguards will continue to be both effective and efficient in the future. This process provides the Department with a comprehensive and coherent planning framework for the short (2 years), medium (6 years) and long (12 years) term. The Department's suite of planning documents includes a long-term strategic plan and an associated long-term research and development plan as well as a biennial development and implementation support programme. The Department's Long-Term Strategic Plan 2012-2023 addresses the conceptual framework for safeguards implementation, legal authority, technical capabilities (expertise, equipment and infrastructure) and the human and financial resources necessary for Agency verification activities. As research and development (R&D) are essential to meet the safeguards needs of the future, the Department-s Long-Term R&D Plan 2012-2023 is designed to support the Long-Term Strategic Plan 2012-2023 by setting out the capabilities that the Department needs to achieve its strategic objectives, and key milestones towards achieving those capabilities for which Member State R&D support is needed. The Long-Term R&D Plan 2012-2023 addresses the Department's R&D requirements in areas such as safeguards concepts and approaches; detection of undeclared nuclear material and activities; safeguards equipment and communication; information technology, collection, analysis and security; analytical services; new mandates; and training. Long-term capabilities discussed in the presentation include deployed systems (e.g., equipment at facilities); analytical (e.g., sample analysis), operational (e.g., staff expertise and skills) and readiness (e.g., safeguarding new types of facilities) capabilities. To address near-term development objectives and support the implementation of its verification activities as well as to

  13. Planning Public Transport

    DEFF Research Database (Denmark)

    Andersen, Jonas Lohmann Elkjær; Landex, Alex

    2009-01-01

    This good practice guide is composed for the master course 13120 Public Transport Planning held at the Department of Transport, Technical University of Denmark. It is intended to use as guide in the different planning aspects and assignments of the course. Since the course is about the planning...... of new public transport infrastructure this guide also focuses on the planning of new infrastructure. Furthermore, the new infrastructure in the course is expected to be a light rail and even though this guide aims at being general for public transport some of the issues evidently become more relevant...... will enable a capability for planning both bus and rail. The guide is build as a full sketch investigation of a new public transport project ranging chronological from project clarification to physical and timetable planning to traffic modeling and project appraisal. The same steps that are expected...

  14. Business plan competition

    CERN Multimedia

    2007-01-01

    "Venture – Companies for tomorrow" is a business plan competition, which supports students and other junior entrepreneurs in developing their business plans. The sixth edition of the competition is now taking place. Venture 2008 highlights: - prize money totalling CHF 150’000; - possibility to optimize business ideas and business plans with the help of experienced coaches: around 200 coaches are available, with a wide range of backgrounds, entrepreneurs as well as venture capitalists; -\tpossibility to present business ideas and business plans to potential investors ("Investor Days" - 17 January and 7 May); - active involvement in the start-up community; -\tcontribution to potential independence. The competition consists of two phases: Phase I, Business idea, Deadline for submission of business idea: 5 December 2007 (online at http://www.venture.ch). Award Ceremony: 17 January 2008 Phase II, Business plan Deadline for submission of business plan: 2 April 2008 (online at...

  15. Planning oral narrative tasks: optimizing strategic planning condition through strategy instruction

    Directory of Open Access Journals (Sweden)

    André Luís Specht

    2017-06-01

    Full Text Available This article presents the results of a master thesis, which aimed at investigating the impact of strategic planning instruction on the speech performance of 6 L2 Brazilian learners. The participants, Letras-Inglês students, performed three now-and-there picture-cued narrative tasks under three different conditions: (1 no planning, (2 planning before instruction, and (3 planning after instruction. In addition, the participants filled in post-task questionnaires after the performance of each task, aiming at understanding their opinion on the conditions and tasks. Quantitative and qualitative analyses were conducted in order to examine participants’ oral production and perception, respectively. In general, there was no statistical evidence supporting the impact of instruction on participants’ oral planned performance; however, some statistical results approached significance, which may suggest some positive effects. Qualitative analyses provided positive evidence of the impact of strategic planning instruction on participant perception and their use of strategies during planning time. Moreover, the results of this study can contribute to the fields of Second Language Acquisition and Language Pegadogy.

  16. Planning and Foucault

    DEFF Research Database (Denmark)

    Flyvbjerg, Bent; Richardson, Tim

    In this paper we argue that the use of the communicative theory of Jürgen Habermas in planning theory is problematic because it hampers an understanding of how power shapes planning. We posit an alternative approach based on the power analytics of Michel Foucault which focuses on "what is actually...... done", as opposed to Habermas`  focus on "what should be done". We discuss how the Foucauldian stance problematises planning, asking difficult questions about the treatment of legitimacy, rationality, knowledge and spatiality. We conclude that Foucault offers a type of analytic planning theory which...... offers better prospects than does Habermas for those interested in understanding and bringing about democratic social change through planning....

  17. Planning and Foucault

    DEFF Research Database (Denmark)

    Flyvbjerg, Bent; Richardson, Tim

    2002-01-01

    In this paper we argue that the use of the communicative theory of Jürgen Habermas in planning theory is problematic because it hampers an understanding of how power shapes planning. We posit an alternative approach based on the power analytics of Michel Foucault which focuses on ?what is actually...... done?, as opposed to Habermas?s focus on ?what should be done?. We discuss how the Foucauldian stance problematises planning, asking difficult questions about the treatment of legitimacy, rationality, knowledge and spatiality. We conclude that Foucault offers a type of analytic planning theory which...... offers better prospects than does Habermas for those interested in understanding and bringing about democratic social change through planning....

  18. Planning for agroforestry

    NARCIS (Netherlands)

    Budd, W.W.; Duchhart, I.; Hardesty, L.N.; Steiner, F.

    1990-01-01

    In this book a selection of contributions to the international symposium "Planning for agroforestry", held at Washington State University on April 24-27, 1989, is published. First the planning for agroforestry and agroforestry diagnosis and design is viewed over. Then the planning for and

  19. Automation of radiation treatment planning. Evaluation of head and neck cancer patient plans created by the Pinnacle"3 scripting and Auto-Planning functions

    International Nuclear Information System (INIS)

    Speer, Stefan; Weiss, Alexander; Bert, Christoph; Klein, Andreas; Kober, Lukas; Yohannes, Indra

    2017-01-01

    Intensity-modulated radiotherapy (IMRT) techniques are now standard practice. IMRT or volumetric-modulated arc therapy (VMAT) allow treatment of the tumor while simultaneously sparing organs at risk. Nevertheless, treatment plan quality still depends on the physicist's individual skills, experiences, and personal preferences. It would therefore be advantageous to automate the planning process. This possibility is offered by the Pinnacle"3 treatment planning system (Philips Healthcare, Hamburg, Germany) via its scripting language or Auto-Planning (AP) module. AP module results were compared to in-house scripts and manually optimized treatment plans for standard head and neck cancer plans. Multiple treatment parameters were scored to judge plan quality (100 points = optimum plan). Patients were initially planned manually by different physicists and re-planned using scripts or AP. Script-based head and neck plans achieved a mean of 67.0 points and were, on average, superior to manually created (59.1 points) and AP plans (62.3 points). Moreover, they are characterized by reproducibility and lower standard deviation of treatment parameters. Even less experienced staff are able to create at least a good starting point for further optimization in a short time. However, for particular plans, experienced planners perform even better than scripts or AP. Experienced-user input is needed when setting up scripts or AP templates for the first time. Moreover, some minor drawbacks exist, such as the increase of monitor units (+35.5% for scripted plans). On average, automatically created plans are superior to manually created treatment plans. For particular plans, experienced physicists were able to perform better than scripts or AP; thus, the benefit is greatest when time is short or staff inexperienced. (orig.) [de

  20. Automation of radiation treatment planning : Evaluation of head and neck cancer patient plans created by the Pinnacle3 scripting and Auto-Planning functions.

    Science.gov (United States)

    Speer, Stefan; Klein, Andreas; Kober, Lukas; Weiss, Alexander; Yohannes, Indra; Bert, Christoph

    2017-08-01

    Intensity-modulated radiotherapy (IMRT) techniques are now standard practice. IMRT or volumetric-modulated arc therapy (VMAT) allow treatment of the tumor while simultaneously sparing organs at risk. Nevertheless, treatment plan quality still depends on the physicist's individual skills, experiences, and personal preferences. It would therefore be advantageous to automate the planning process. This possibility is offered by the Pinnacle 3 treatment planning system (Philips Healthcare, Hamburg, Germany) via its scripting language or Auto-Planning (AP) module. AP module results were compared to in-house scripts and manually optimized treatment plans for standard head and neck cancer plans. Multiple treatment parameters were scored to judge plan quality (100 points = optimum plan). Patients were initially planned manually by different physicists and re-planned using scripts or AP. Script-based head and neck plans achieved a mean of 67.0 points and were, on average, superior to manually created (59.1 points) and AP plans (62.3 points). Moreover, they are characterized by reproducibility and lower standard deviation of treatment parameters. Even less experienced staff are able to create at least a good starting point for further optimization in a short time. However, for particular plans, experienced planners perform even better than scripts or AP. Experienced-user input is needed when setting up scripts or AP templates for the first time. Moreover, some minor drawbacks exist, such as the increase of monitor units (+35.5% for scripted plans). On average, automatically created plans are superior to manually created treatment plans. For particular plans, experienced physicists were able to perform better than scripts or AP; thus, the benefit is greatest when time is short or staff inexperienced.

  1. Intelligent robot action planning

    Energy Technology Data Exchange (ETDEWEB)

    Vamos, T; Siegler, A

    1982-01-01

    Action planning methods used in intelligent robot control are discussed. Planning is accomplished through environment understanding, environment representation, task understanding and planning, motion analysis and man-machine communication. These fields are analysed in detail. The frames of an intelligent motion planning system are presented. Graphic simulation of the robot's environment and motion is used to support the planning. 14 references.

  2. The nuclear emergency plans

    International Nuclear Information System (INIS)

    Fuertes Menendez, M. J.; Gasco Leonarte, L.; Granada Ferrero, M. J.

    2007-01-01

    Planning of the response to emergencies in nuclear plants is regulated by the Basic Nuclear Emergency Plan (PLABEN). This basic Plan is the guidelines for drawing up, implementing and maintaining the effectiveness of the nuclear power plant exterior nuclear emergency plans. The five exterior emergency plans approved as per PLABEN (PENGUA, PENCA, PENBU, PENTA and PENVA) place special emphasis on the preventive issues of emergency planning, such as implementation of advance information programs to the population, as well as on training exercises and drills. (Author)

  3. When does treatment plan optimization require inverse planning?

    International Nuclear Information System (INIS)

    Sherouse, George W.

    1995-01-01

    Increasing maturity of image-based computer-aided design of three-dimensional conformal radiotherapy has recently sparked a great deal of work in the area of treatment plan optimization. Optimization of a conformal photon beam treatment plan is that exercise through which a set of intensity-modulated static beams or arcs is specified such that, when the plan is executed, 1) a region of homogeneous dose is produced in the patient with a shape which geometrically conforms (within a specified tolerance) to the three-dimensional shape of a designated target volume and 2) acceptably low incidental dose is delivered to non-target tissues. Interest in conformal radiotherapy arise from a fundamental assumption that there is significant value to be gained from aggressive customization of the treatment for each individual patient In our efforts to design optimal treatments, however, it is important to remember that, given the biological and economic realities of clinical radiotherapy, mathematical optimization of dose distribution metrics with respect to some minimal constraint set is not a necessary or even sufficient condition for design of a clinically optimal treatment. There is wide variation in the complexity of the clinical situations encountered in practice and there are a number of non-physical criteria to be considered in planning. There is also a complementary variety of computational and engineering means for achieving optimization. To date, the scientific dialogue regarding these techniques has concentrated on development of solutions to worst-case scenarios, largely in the absence of consideration of appropriate matching of solution complexity to problem complexity. It is the aim of this presentation to propose a provisional stratification of treatment planning problems, stratified by relative complexity, and to identify a corresponding stratification of necessary treatment planning techniques. It is asserted that the subset of clinical radiotherapy cases for

  4. Personal strategic planning

    Directory of Open Access Journals (Sweden)

    Rolando Juan Soliz Estrada

    2011-01-01

    Full Text Available Reconciling personal skills with the demands of a globalized and competitive market has become a pre-requisite for professionals aspiring for success in their careers. The quest for personal fulfillment has encouraged people to search for tools which develop their talents and balance their efforts, in order to achieve a better, happier and healthier life. As an option, planning, which historically was restricted to being an organizational tool, today has also come to be used by individuals who desire personal success. In this way, the objective of this article is to develop a model of Personal Strategic Planning which takes into account the various operation areas and human performance. The proposed model is divided into: Individual Planning, Professional Planning, Family Planning, Personal Business Planning and Political Participation, Social and Religious/Spiritual Planning and their respective fields. In order to analyse and validate the model, exploratory research of a qualitative nature was used through primary and secondary data sources. From the results obtained by the model, it is possible to consider their importance to future research, once the studied areas can be developed in subsequent works.

  5. Interactive Energy Planning

    DEFF Research Database (Denmark)

    Blarke, Morten Boje

    2006-01-01

    Though it is being questioned whether planning theory should be fitted into neat typologies, some have described evolving planning theory as a journey away from ethnocentrism, through the lands of rationalism, pragmatism, socio-ecological idealism, political-economic mobilization, currently...... anchoring along the shores of the land of communications and collaboration. Whether or not a particular typology is applicable, theory and praxis are establishing standpoints, which strengthens our understanding of the planning complex, and which should inspire improved energy planning methodologies...

  6. Marketing plan

    OpenAIRE

    Jantunen, Essi; Hellman, Annika

    2012-01-01

    The aim of this bachelor’s thesis was to draw up an efficient marketing plan for Pohjolan Vihreä Polku Oy, which offers meeting and nature activity services. The company was in a process of conversion and needed a structured marketing plan. The objectives of the company were perceived through severe research. The main purposes of the marketing plan were to raise the visibility of the company and increase its clientele. The proposed marketing actions are also to be used to improve the company’...

  7. Operating plan FY 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-10-01

    This document is the first edition of Argonne`s new Operating Plan. The Operating Plan complements the strategic planning in the Laboratory`s Institutional Plan by focusing on activities that are being pursued in the immediate fiscal year, FY 1998. It reflects planning that has been done to date, and it will serve in the future as a resource and a benchmark for understanding the Laboratory`s performance. The heart of the Institutional Plan is the set of major research initiatives that the Laboratory is proposing to implement in future years. In contrast, this Operating Plan focuses on Argonne`s ongoing R&D programs, along with cost-saving measures and other improvements being implemented in Laboratory support operations.

  8. Setup planning for machining

    CERN Document Server

    Hazarika, Manjuri

    2015-01-01

    Professionals as well as researchers can benefit from this comprehensive introduction into the topic of setup planning, which reflects the latest state of research and gives hands-on examples. Starting with a brief but thorough introduction, this book explains the significance of setup planning in process planning and includes a reflection on its external constraints. Step-by-step the different phases of setup planning are outlined and traditional as well as modern approaches, such as fuzzy logic based setup planning, on the solution of setup planning problems are presented. Three detailed examples of applications provide a clear and accessible insight into the up-to-date techniques and various approaches in setup planning.

  9. Public affairs plan

    International Nuclear Information System (INIS)

    1995-09-01

    The purpose of the Uranium Mill Tailings Remedial Action (UMTRA) Project Public Affairs Plan is to establish goals for the fiscal year (FY) 1996 UMTRA Project public affairs program and to identify specific activities to be conducted during the year. It describes the roles of various agencies involved in the public affairs program and defines the functions of the UMTRA Project Technical Assistance Contractor (TAC) Public Affairs Department. It replaces the FY 1995 Public Affairs Plan (DOE/AL/62350-154). The plan also describes the US Department of Energy's (DOE) plans to keep stakeholders and other members of the public informed about UMTRA Project policies, plans, and activities, and provide opportunities for stakeholders and interested segments of the public to participate in UMTRA Project decision-making processes. The plan applies to the UMTRA Project Team; the DOE Grand Junction Projects Office (GJPO); the DOE Albuquerque Operations Office, Office of Public Affairs (OPA); the TAC; the UMTRA Project Remedial Action Contractor (RAC); and other cooperating agencies

  10. Planning for information systems

    CERN Document Server

    King, William R

    2015-01-01

    Edited by one of the best-known and most widely respected figures in the field, ""Planning for Information Systems"" is a comprehensive, single source overview of the myriad ideas and processes that are identified with IS planning. While many chapters deal with high level strategic planning, the book gives equal attention to on-the-ground planning issues.Part I, 'Key Concepts of IS Planning', focuses on how IS planning has evolved over the years; business-IS strategic alignment; and the role of dynamic organizational capabilities in leveraging IS competencies. Part II, 'The Organizational IS P

  11. Views on planning and expectations of SEA: the case of transport planning

    International Nuclear Information System (INIS)

    Hilden, Mikael; Furman, Eeva; Kaljonen, Minna

    2004-01-01

    This paper examines the effectiveness of strategic environmental assessment (SEA) in transport planning in the light of different views of planning: synoptic optimising planning, communicative planning and planning as a social struggle. The analysis uses empirical materials from 17 case studies collected by survey from Member Countries of the United Nation's Economic Commission for Europe (UN/ECE) and further processed in a practitioners' workshop, and also a detailed case study carried out in Finland. The case studies and the workshop identified a set of necessary conditions and facilitating factors that contribute to the effectiveness of strategic environmental assessments in transport planning. Our findings suggest that transport planning can often best be characterised as a social struggle over problem definitions and future choices. Thus, the effectiveness of SEA will depend on how well the assessment fits into the planning context and on its actual contribution to debates on problem definitions. Specific procedural steps may improve the effectiveness but explicit requirements to recognise SEA in decision making are likely to be a key condition

  12. An Analysis of Plan Robustness for Esophageal Tumors: Comparing Volumetric Modulated Arc Therapy Plans and Spot Scanning Proton Planning

    International Nuclear Information System (INIS)

    Warren, Samantha; Partridge, Mike; Bolsi, Alessandra; Lomax, Anthony J.; Hurt, Chris; Crosby, Thomas; Hawkins, Maria A.

    2016-01-01

    Purpose: Planning studies to compare x-ray and proton techniques and to select the most suitable technique for each patient have been hampered by the nonequivalence of several aspects of treatment planning and delivery. A fair comparison should compare similarly advanced delivery techniques from current clinical practice and also assess the robustness of each technique. The present study therefore compared volumetric modulated arc therapy (VMAT) and single-field optimization (SFO) spot scanning proton therapy plans created using a simultaneous integrated boost (SIB) for dose escalation in midesophageal cancer and analyzed the effect of setup and range uncertainties on these plans. Methods and Materials: For 21 patients, SIB plans with a physical dose prescription of 2 Gy or 2.5 Gy/fraction in 25 fractions to planning target volume (PTV)_5_0_G_y or PTV_6_2_._5_G_y (primary tumor with 0.5 cm margins) were created and evaluated for robustness to random setup errors and proton range errors. Dose–volume metrics were compared for the optimal and uncertainty plans, with P<.05 (Wilcoxon) considered significant. Results: SFO reduced the mean lung dose by 51.4% (range 35.1%-76.1%) and the mean heart dose by 40.9% (range 15.0%-57.4%) compared with VMAT. Proton plan robustness to a 3.5% range error was acceptable. For all patients, the clinical target volume D_9_8 was 95.0% to 100.4% of the prescribed dose and gross tumor volume (GTV) D_9_8 was 98.8% to 101%. Setup error robustness was patient anatomy dependent, and the potential minimum dose per fraction was always lower with SFO than with VMAT. The clinical target volume D_9_8 was lower by 0.6% to 7.8% of the prescribed dose, and the GTV D_9_8 was lower by 0.3% to 2.2% of the prescribed GTV dose. Conclusions: The SFO plans achieved significant sparing of normal tissue compared with the VMAT plans for midesophageal cancer. The target dose coverage in the SIB proton plans was less robust to random setup errors and might be

  13. An Analysis of Plan Robustness for Esophageal Tumors: Comparing Volumetric Modulated Arc Therapy Plans and Spot Scanning Proton Planning

    Energy Technology Data Exchange (ETDEWEB)

    Warren, Samantha, E-mail: samantha.warren@oncology.ox.ac.uk [Cancer Research UK/Medical Research Council Oxford Institute for Radiation Oncology, Gray Laboratories, University of Oxford, Oxford (United Kingdom); Partridge, Mike [Cancer Research UK/Medical Research Council Oxford Institute for Radiation Oncology, Gray Laboratories, University of Oxford, Oxford (United Kingdom); Bolsi, Alessandra; Lomax, Anthony J. [Centre for Proton Therapy, Paul Scherrer Institute, Villigen (Switzerland); Hurt, Chris [Wales Cancer Trials Unit, School of Medicine, Heath Park, Cardiff (United Kingdom); Crosby, Thomas [Velindre Cancer Centre, Velindre Hospital, Cardiff (United Kingdom); Hawkins, Maria A. [Cancer Research UK/Medical Research Council Oxford Institute for Radiation Oncology, Gray Laboratories, University of Oxford, Oxford (United Kingdom)

    2016-05-01

    Purpose: Planning studies to compare x-ray and proton techniques and to select the most suitable technique for each patient have been hampered by the nonequivalence of several aspects of treatment planning and delivery. A fair comparison should compare similarly advanced delivery techniques from current clinical practice and also assess the robustness of each technique. The present study therefore compared volumetric modulated arc therapy (VMAT) and single-field optimization (SFO) spot scanning proton therapy plans created using a simultaneous integrated boost (SIB) for dose escalation in midesophageal cancer and analyzed the effect of setup and range uncertainties on these plans. Methods and Materials: For 21 patients, SIB plans with a physical dose prescription of 2 Gy or 2.5 Gy/fraction in 25 fractions to planning target volume (PTV){sub 50Gy} or PTV{sub 62.5Gy} (primary tumor with 0.5 cm margins) were created and evaluated for robustness to random setup errors and proton range errors. Dose–volume metrics were compared for the optimal and uncertainty plans, with P<.05 (Wilcoxon) considered significant. Results: SFO reduced the mean lung dose by 51.4% (range 35.1%-76.1%) and the mean heart dose by 40.9% (range 15.0%-57.4%) compared with VMAT. Proton plan robustness to a 3.5% range error was acceptable. For all patients, the clinical target volume D{sub 98} was 95.0% to 100.4% of the prescribed dose and gross tumor volume (GTV) D{sub 98} was 98.8% to 101%. Setup error robustness was patient anatomy dependent, and the potential minimum dose per fraction was always lower with SFO than with VMAT. The clinical target volume D{sub 98} was lower by 0.6% to 7.8% of the prescribed dose, and the GTV D{sub 98} was lower by 0.3% to 2.2% of the prescribed GTV dose. Conclusions: The SFO plans achieved significant sparing of normal tissue compared with the VMAT plans for midesophageal cancer. The target dose coverage in the SIB proton plans was less robust to random setup

  14. Knowledge-based radiation therapy (KBRT) treatment planning versus planning by experts: validation of a KBRT algorithm for prostate cancer treatment planning

    International Nuclear Information System (INIS)

    Nwankwo, Obioma; Mekdash, Hana; Sihono, Dwi Seno Kuncoro; Wenz, Frederik; Glatting, Gerhard

    2015-01-01

    A knowledge-based radiation therapy (KBRT) treatment planning algorithm was recently developed. The purpose of this work is to investigate how plans that are generated with the objective KBRT approach compare to those that rely on the judgment of the experienced planner. Thirty volumetric modulated arc therapy plans were randomly selected from a database of prostate plans that were generated by experienced planners (expert plans). The anatomical data (CT scan and delineation of organs) of these patients and the KBRT algorithm were given to a novice with no prior treatment planning experience. The inexperienced planner used the knowledge-based algorithm to predict the dose that the OARs receive based on their proximity to the treated volume. The population-based OAR constraints were changed to the predicted doses. A KBRT plan was subsequently generated. The KBRT and expert plans were compared for the achieved target coverage and OAR sparing. The target coverages were compared using the Uniformity Index (UI), while 5 dose-volume points (D 10 , D 30, D 50 , D 70 and D 90 ) were used to compare the OARs (bladder and rectum) doses. Wilcoxon matched-pairs signed rank test was used to check for significant differences (p < 0.05) between both datasets. The KBRT and expert plans achieved mean UI values of 1.10 ± 0.03 and 1.10 ± 0.04, respectively. The Wilcoxon test showed no statistically significant difference between both results. The D 90 , D 70, D 50 , D 30 and D 10 values of the two planning strategies, and the Wilcoxon test results suggests that the KBRT plans achieved a statistically significant lower bladder dose (at D 30 ), while the expert plans achieved a statistically significant lower rectal dose (at D 10 and D 30 ). The results of this study show that the KBRT treatment planning approach is a promising method to objectively incorporate patient anatomical variations in radiotherapy treatment planning

  15. Planning ahead

    Energy Technology Data Exchange (ETDEWEB)

    Davies, J. [Mintec Inc. (US)

    2004-09-01

    The paper presents a state-of-the-art mine planning program that facilitates data storage and provides easy access to essential mine information. MineSight from Mintec, Inc., and the addition MineSight 3D provide a powerful tool used by major coal companies worldwide, offering modelling of different deposit types and complete planning tools including advanced surface/surface and solid/surface intersection routines. The new MineSight Operations addition helps to streamline the planning process and store raw blasthole data (in acQuire) and essential cut attribute information. 12 figs.

  16. Data-Driven Planning: Using Assessment in Strategic Planning

    Science.gov (United States)

    Bresciani, Marilee J.

    2010-01-01

    Data-driven planning or evidence-based decision making represents nothing new in its concept. For years, business leaders have claimed they have implemented planning informed by data that have been strategically and systematically gathered. Within higher education and student affairs, there may be less evidence of the actual practice of…

  17. Urban sustainability through strategic planning: A case of metropolitan planning in Khulna city, Bangladesh

    Directory of Open Access Journals (Sweden)

    Md. Ashiq Ur Rahman

    2016-06-01

    Full Text Available Planning is a crucial element for any development initiative. Planning entails choice making in pursuit of stated goals e.g. improving living conditions for individuals and societies. Planning initiatives are employed within social systems that are governed by institution, and planning intervenes with and may reconfigure these institutions resulting in social change. This paper discusses how urban sustainability can be achieved through strategic action in urban development by analysing the planning process of Khulna city, Bangladesh. This paper reviews different scholarly articles to draw a conceptual framework for identifying the interface of strategic planning, components of strategic action planning and urban sustainability. Based on this conceptual framework this paper identifies the scope of achieving urban sustainability through analysing the current planning practice of Khulna city, Bangladesh. This paper identifies that though the Khulna city plan adopted the approach of strategic planning but it failed to comply with its theoretical notion to achieve the issues related to urban sustainability. Analysis reveals that in terms of social attribute that recognizes the interest of different group of people the exiting planning packages is not sustainable. Similar phenomenon have been observed in terms of recognition of gender and marginalized people in planning, equitable provision of income and employment generation, peoples’ participation in planning and polices for ensuring equitable access to infrastructure services. Therefore the existing planning package of Khulna city failed to achieve the issues of urban sustainability through its adapted strategic planning approach.

  18. Marketing Planning: Feeniks Koulu

    OpenAIRE

    Raut, Biranjan

    2013-01-01

    Degree Thesis “Marketing Planning: Feeniks Koulu” demonstrates structured marketing planning process with the help of case company “Feeniks Koulu”. The central idea of Thesis is to come up with systematic marketing plan following structured process. Thesis employs qualitative research methodology following inductive reasoning approach. Thesis, initiates by outlining theoretical planning methods, which then is materialized into marketing plan with the help of empirical research. Discussion and...

  19. The Importance of a Business Plan when Planning a ...

    African Journals Online (AJOL)

    The Importance of a Business Plan when Planning a Lexicographical Project* ... It is, however, an important step towards the establishment of a dictionary project. The compilation of a dictionary ... AJOL African Journals Online. HOW TO USE ...

  20. SU-E-T-173: Clinical Comparison of Treatment Plans and Fallback Plans for Machine Downtime

    Energy Technology Data Exchange (ETDEWEB)

    Cruz, W [University of Texas Health Science Center at San Antonio, San Antonio, TX (United States); Cancer Therapy and Research Center, San Antonio, TX (United States); Papanikolaou, P [University of Texas Health Science Center at San Antonio, San Antonio, TX (United States); Mavroidis, P [University of North Carolina, Chapel Hill, NC (United States); Stathakis, S [Cancer Therapy and Research Center, San Antonio, TX (United States)

    2015-06-15

    Purpose: The purpose of this study was to determine the clinical effectiveness and dosimetric quality of fallback planning in relation to machine downtime. Methods: Plans for a Varian Novalis TX were mimicked, and fallback plans using an Elekta VersaHD machine were generated using a dual arc template. Plans for thirty (n=30) patients of various treatment sites optimized and calculated using RayStation treatment planning system. For each plan, a fall back plan was created and compared to the original plan. A dosimetric evaluation was conducted using the homogeneity index, conformity index, as well as DVH analysis to determine the quality of the fallback plan on a different treatment machine. Fallback plans were optimized for 60 iterations using the imported dose constraints from the original plan DVH to give fallback plans enough opportunity to achieve the dose objectives. Results: The average conformity index and homogeneity index for the NovalisTX plans were 0.76 and 10.3, respectively, while fallback plan values were 0.73 and 11.4. (Homogeneity =1 and conformity=0 for ideal plan) The values to various organs at risk were lower in the fallback plans as compared to the imported plans across most organs at risk. Isodose difference comparisons between plans were also compared and the average dose difference across all plans was 0.12%. Conclusion: The clinical impact of fallback planning is an important aspect to effective treatment of patients. With the complexity of LINACS increasing every year, an option to continue treating during machine downtime remains an essential tool in streamlined treatment execution. Fallback planning allows the clinic to continue to run efficiently should a treatment machine become offline due to maintenance or repair without degrading the quality of the plan all while reducing strain on members of the radiation oncology team.

  1. Subseabed Disposal Program Plan. Volume II. FY80 budget and subtask work plans

    International Nuclear Information System (INIS)

    1980-01-01

    This volume of the Subseabed Disposal Program Plan presents a breakdown of the master program structure by major activity. Each activity is described and accompanied by a specific cost plan schedule and a milestone plan. The costs have been compiled in the Cost Plan Schedules attached to each Subtask Work Plan. The FY 1980 budget for the Subseabed Disposal Program is summarized at the second level of the Work Breakdown Structure. The milestone plans for FY 80 are presented. The milestones can be changed only with the concurrence of the Sandia Subseabed Program Manager

  2. Analysis of The Planning Education in the Light of the Contemporary Trends in Planning

    Science.gov (United States)

    Husar, Milan; Ceren Varis, Sila; Ondrejicka, Vladimir

    2017-12-01

    This paper examines the way the planning education is taught and examines the recent trends in the curricula of planning education institutions. The introduction of changing economic systems and planning in the field of education is discussed against these changes. Additionally, the evolution in the planner’s role and how it affects the planning education is discussed. The paper is addressing trends and challenges the countries and their planning changes are facing in 21st century. The trends such as increasing globalization, fuzziness of spatial structures and their borders, complexity and uncertainty and the growing interconnectedness of the world are discussed. Another aim is to prepare a common ground, a platform at the university level for scientific cooperation in the field of planning. This study aims at examining the situation of planning in the contemporary world. The identified challenges include the need for more flexibility in planning and planning education, the emergence of innovations and creativity in planners and planning projects, the necessity of promoting soft skills while keeping the existing technical nature of planning and lastly, the need for more interdisciplinary work. The final part of the paper is discussing the future planning education and recommendations on how the schools of planning should reflect these changes.

  3. Reasoning about plans

    CERN Document Server

    Allen, James; Pelavin, Richard; Tenenberg, Josh

    1991-01-01

    This book presents four contributions to planning research within an integrated framework. James Allen offers a survey of his research in the field of temporal reasoning, and then describes a planning system formalized and implemented directly as an inference process in the temporal logic. Starting from the same logic, Henry Kautz develops the first formal specification of the plan recognition process and develops a powerful family of algorithms for plan recognition in complex situations. Richard Pelavin then extends the temporal logic with model operators that allow the representation to

  4. 75 FR 26270 - Environmental Planning and Historic Preservation Compliance Costs Policy; Environmental Planning...

    Science.gov (United States)

    2010-05-11

    ...] Environmental Planning and Historic Preservation Compliance Costs Policy; Environmental Planning and Historic... draft Environmental Planning and Historic Preservation Compliance Costs policy and a draft Environmental Planning and Historic Preservation Mitigation policy. DATES: Comments must be received by June 10, 2010...

  5. 7 CFR 1210.303 - Plan.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Plan. 1210.303 Section 1210.303 Agriculture... PLAN Watermelon Research and Promotion Plan Definitions § 1210.303 Plan. Plan means this watermelon research and promotion Plan issued by the Secretary pursuant to the Act. ...

  6. Health Workforce Planning

    Science.gov (United States)

    Al-Sawai, Abdulaziz; Al-Shishtawy, Moeness M.

    2015-01-01

    In most countries, the lack of explicit health workforce planning has resulted in imbalances that threaten the capacity of healthcare systems to attain their objectives. This has directed attention towards the prospect of developing healthcare systems that are more responsive to the needs and expectations of the population by providing health planners with a systematic method to effectively manage human resources in this sector. This review analyses various approaches to health workforce planning and presents the Six-Step Methodology to Integrated Workforce Planning which highlights essential elements in workforce planning to ensure the quality of services. The purpose, scope and ownership of the approach is defined. Furthermore, developing an action plan for managing a health workforce is emphasised and a reviewing and monitoring process to guide corrective actions is suggested. PMID:25685381

  7. Customer-focused planning: Beyond integrated resource planning

    International Nuclear Information System (INIS)

    Hastings, P.C.

    1992-01-01

    Integrated resource planning (IRP) evolved from the growing recognition by utilities and regulators that efforts to influence the use of electricity by customers could be more cost-effective than simply expanding the generation system. Improvements in IRP methodology are taking many different forms. One major effort is to move planning closer to the customer. Customer-focused planning (CFP) starts with customer values and uses these to drive decision-making within the utility. CFP is process- rather than product- oriented and typically operates at the bulk power system level. Options available to meet customer needs include electricity, alternative fuels, capital substitution, and end-use management or control. The customer selects the option(s) based on a value set that typically includes safety, reliability, convenience, and cost. There are also four possible levels of decision-making: the end-use; customer/power meter; transmission/distribution interface; and the utility bulk power system. Challenges of implementing CFP include identifying customer wants, needs, and values; integration of utility planning efforts; and the dynamics of the CFP process, in which costs can change with each modification of the transmission and distribution system. Two examples of recent moves toward CFP at Central Maine Power are reviewed. 2 refs., 1 fig

  8. Human-scientific Planning Theory

    OpenAIRE

    Hagen, Aksel

    1998-01-01

    This working report is a paper written to XII AESOP Congress 22 – 25 July 1998, Aveiro, Portugal. It is a presentation of human-scientific action theory and its linkage to planning, both planning theory and planning practice. Human-scientific action theory is created by professor Gunnar Olsson and professor José Luis Ramírez, Nordic School of Planning, Stockholm. Planning is primarily a practical and reflective activity. The notion ”Planning” may, therefore, describe the activi...

  9. Village family planning volunteers in Indonesia: their role in the family planning programme.

    Science.gov (United States)

    Utomo, Iwu Dwisetyani; Arsyad, Syahmida S; Hasmi, Eddy Nurul

    2006-05-01

    Family planning was once a sensitive issue in Indonesia, but today it is considered essential. This paper reports on a study in 1997-98 of the role of village family planning volunteers and the cadres who worked under them in West Java, Central Java and DI Yogyakarta, in implementing the national family planning programme in Indonesia. A total of 108 village family planning volunteers, 108 family planning cadres, 108 local leaders and 324 couples eligible for family planning from 36 villages in the three provinces were interviewed. The volunteers and cadres have made a significant contribution to the implementation of the family planning programme. They promote family planning, organise meetings, provide information, organise income-generation activities, give savings and credit assistance, collect and report data and deliver other family welfare services. Teachers, wives of government officials and others recognised by the community as better off in terms of education and living conditions were most often identified to become family planning volunteers. Because they are women and because they are the most distant arm of the programme, their work is taken for granted. As their activities are directed towards women, especially in women's traditional roles, the programme tends to entrench the existing gender gap in responsibility for family planning and family welfare.

  10. Evaluation of Plan Implementation: Peri-urban Development and the Shanghai Master Plan 1999-2020

    Directory of Open Access Journals (Sweden)

    Jinghuan He

    2015-01-01

    Full Text Available Since the 1980s China has experienced unprecedented urbanisation as a result of a series of reforms promoting rapid economic development. Shanghai, like the other big cities along China’s coastline, has witnessed extraordinary growth in its economy and population with industrial development and rural-to-urban migration generating extensive urban expansion. Shanghai’s GDP growth rate has been over 10 per cent for more than 15 years. Its population in 2013 was estimated at 23.47 million, which is double its size in 1979. The urban area enlarged by four times from 644 to 2,860 km2 between 1977 and 2010. Such demanding growth and dramatic changes present big challenges for urban planning practice in Shanghai. Plans have not kept up with development and the mismatch between the proposals in plans and the actual spatial development has gradually increased, reaching a critical level since 2000. The mismatch in the periurban areas is more notable than that in the existing urban area, but there has not been a systematic review of the relationship between plan and implementation. Indeed, there are few studies on the evaluation of plan implementation in China generally. Although many plans at numerous spatial levels are successively prepared and revised, only few of them have been evaluated in terms of their effectiveness and implementation.  This particularly demanding context for planning where spatial development becomes increasingly unpredictable and more difficult to influence presents an opportunity to investigate the role of plans under conditions of rapid urbanisation. The research project asks to what extent have spatial plans influenced the actual spatial development in the peri-urban areas of Shanghai? The research pays particular attention to the role of the Shanghai Master Plan 1999-2020 (Plan 1999. By answering the main research question this study seeks to contribute to a better understanding of present planning practice in Shanghai

  11. TrainerPlan : Tu plan de entrenamientos en tu móvil

    OpenAIRE

    López de Aberasturi Ortiz de Pinedo, Aitor

    2017-01-01

    TrainerPlan es una aplicación móvil desarrollada para terminales Android que permitirá la generación y consulta de planes de entrenamiento que podrán ser compartidos por diferentes usuarios. TrainerPlan és una aplicació mòbil desenvolupada per a terminals Android que permetrà la generació i consulta de plans d'entrenament que podran ser compartits per diferents usuaris. TrainerPlan is a mobile application developed for Android terminals that will allow the generation and consultation of...

  12. Factor 4 planning

    International Nuclear Information System (INIS)

    Bariol-Mathais, Brigitte; Lavoillotte, Philippine; Gall-Sorrentino, Florence; Malez, Marianne; Sanna, Daniela; Marsauche, Maud; Marquet, Sarah; Debergue, Sophie; Aminu, Olufunmi; Bernard, Helene; Marchand, Jean-Michel; Blin, Frederic; Grange, Jerome; Caillierez, Sophie; Muller, Dania; Clement, Bob; Desire, Jean-Charles; Metais, Benedicte; Lannuzel, Philippe; Pezet-Kuhn, Murielle; Pons, Anne; Rivoire-Meley, Benedicte; Tissot, Heloise

    2015-07-01

    Factor 4 is the goal of cutting our greenhouse gas emissions by 75% by 2050. Achieving this objective will necessitate radical changes in our practices, in particular concerning transport and housing; the measures currently implemented, such as positive-energy buildings, low-impact mobility and eco-neighbourhoods, will not be enough to meet this goal. These measures must be conceived in the framework of broad territorial planning that integrates environmental and energy objectives far upstream. To this end, the French Environment and Energy Management Agency (ADEME) and the French network of Urban Planning Agencies (FNAU), pursuing their missions in their respective areas of competence, have joined forces to make infrastructure and land use planning an integral part of the environmental and energy transition process. In 2013, the two organisations signed a partnership agreement and compiled an inventory of practices that are relevant to Factor 4 planning. This work was led by Epures, Saint-etienne urban planning agency, along with FNAU, drawing upon the expertise of a dozen urban planning agencies in precursor territories. This inventory describes the stakes, resources and strengths for each territory, which have led to cross-sectoral territorial planning exercises with ambitious environmental and energy objectives; the importance of evaluation in attaining these goals is emphasised. Current experience, questions and available methodological tools are summarised in this document, to encourage territories and help them design their planning policies along a trajectory to achieve Factor 4 goals. The compilation also aims to be a contribution to the COP21 climate conference

  13. Account-based retiree medical plans: what's good for your pension plan may be good for your retiree medical plan.

    Science.gov (United States)

    Ruschau, W J

    2001-09-01

    Many of the same forces that caused employers to gravitate toward account-based pension plans are beginning to spark similar changes in retiree medical plans. As medical costs continue to escalate, account-based retiree medical plans offer a new way to manage company outlays, while preserving an important benefit for retirees.

  14. Automating Space Station operations planning

    Science.gov (United States)

    Ziemer, Kathleen A.

    1989-01-01

    The development and implementation of the operations planning processes for the Space Station are discussed. A three level planning process, consisting of strategic, tactical, and execution level planning, is being developed. The integration of the planning procedures into a tactical planning system is examined and the planning phases are illustrated.

  15. 1990-1991 Marketing Plan. Year II: Planning To Meet the Future.

    Science.gov (United States)

    Turcott, Frances; And Others

    In Maryland, Catonsville Community College's (CCC) 1990-91 marketing plan deals with the community's perceptions of the institution and strategies to improve CCC's image. Both the 1989-90 and 1990-91 plans targeted the same markets for special recruitment strategies; i.e., high school graduates with transfer plans, part-time adult students,…

  16. Research Planning Process

    Science.gov (United States)

    Lofton, Rodney

    2010-01-01

    This presentation describes the process used to collect, review, integrate, and assess research requirements desired to be a part of research and payload activities conducted on the ISS. The presentation provides a description of: where the requirements originate, to whom they are submitted, how they are integrated into a requirements plan, and how that integrated plan is formulated and approved. It is hoped that from completing the review of this presentation, one will get an understanding of the planning process that formulates payload requirements into an integrated plan used for specifying research activities to take place on the ISS.

  17. Lognormal Distribution of Cellular Uptake of Radioactivity: Statistical Analysis of α-Particle Track Autoradiography

    Science.gov (United States)

    Neti, Prasad V.S.V.; Howell, Roger W.

    2010-01-01

    Recently, the distribution of radioactivity among a population of cells labeled with 210Po was shown to be well described by a log-normal (LN) distribution function (J Nucl Med. 2006;47:1049–1058) with the aid of autoradiography. To ascertain the influence of Poisson statistics on the interpretation of the autoradiographic data, the present work reports on a detailed statistical analysis of these earlier data. Methods The measured distributions of α-particle tracks per cell were subjected to statistical tests with Poisson, LN, and Poisson-lognormal (P-LN) models. Results The LN distribution function best describes the distribution of radioactivity among cell populations exposed to 0.52 and 3.8 kBq/mL of 210Po-citrate. When cells were exposed to 67 kBq/mL, the P-LN distribution function gave a better fit; however, the underlying activity distribution remained log-normal. Conclusion The present analysis generally provides further support for the use of LN distributions to describe the cellular uptake of radioactivity. Care should be exercised when analyzing autoradiographic data on activity distributions to ensure that Poisson processes do not distort the underlying LN distribution. PMID:18483086

  18. Topology and immersion depth of an integral membrane protein by paramagnetic rates from dissolved oxygen.

    Science.gov (United States)

    Al-Abdul-Wahid, M Sameer; Verardi, Raffaello; Veglia, Gianluigi; Prosser, R Scott

    2011-09-01

    In studies of membrane proteins, knowledge of protein topology can provide useful insight into both structure and function. In this work, we present a solution NMR method for the measurement the tilt angle and average immersion depth of alpha helices in membrane proteins, from analysis of the paramagnetic relaxation rate enhancements arising from dissolved oxygen. No modification to the micelle or protein is necessary, and the topology of both transmembrane and amphipathic helices are readily determined. We apply this method to the measure the topology of a monomeric mutant of phospholamban (AFA-PLN), a 52-residue membrane protein containing both an amphipathic and a transmembrane alpha helix. In dodecylphosphocholine micelles, the amphipathic helix of AFA-PLN was found to have a tilt angle of 87° ± 1° and an average immersion depth of 13.2 Å. The transmembrane helix was found to have an average immersion depth of 5.4 Å, indicating residues 41 and 42 are closest to the micelle centre. The resolution of paramagnetic relaxation rate enhancements from dissolved oxygen compares favourably to those from Ni (II), a hydrophilic paramagnetic species.

  19. Survey Potensi Pembangkit Listrik Tenaga Mikro Hidro di Kuta Malaka Kabupaten Aceh Besar Propinsi Nanggroe Aceh Darussalam

    Directory of Open Access Journals (Sweden)

    Ridwan Arief Subekti

    2012-03-01

    Full Text Available Generator set is one of the devices able to produces electrics. Generator set used when electrics supply of PLN insufficient or even there no. This matter experienced in Kuta Malaka, Aceh Besar, Nanggroe Aceh Darussalam there will be developed a tour area. Because electrical supply from PLN not yet, power electric to support the area used generator set. Future, that tour area apply hydro power station for electrical energy requirement. From that background, the purpose of water potential survey was conducted to get beginning data and information of water power potential as reference to develop PLTMH. The potential survey cover determination of location and head measurement use global positioning system Garmin GPSMAP 76CSx. The other using altimeter, head also was measure manually used the meter by spirit level and string method. The river rate of flow measurement within measuring to speed of rivers flow use propeller devices or current meters brand Flowatch. From data of PLTMH potential survey in Kuta Malaka area known that there are three potential locations able to be developed as PLTMH with effective head 5 until 16 meter and output power 3.7 until 9.1 kW.

  20. Topology and immersion depth of an integral membrane protein by paramagnetic rates from dissolved oxygen

    International Nuclear Information System (INIS)

    Al-Abdul-Wahid, M. Sameer; Verardi, Raffaello; Veglia, Gianluigi; Prosser, R. Scott

    2011-01-01

    In studies of membrane proteins, knowledge of protein topology can provide useful insight into both structure and function. In this work, we present a solution NMR method for the measurement the tilt angle and average immersion depth of alpha helices in membrane proteins, from analysis of the paramagnetic relaxation rate enhancements arising from dissolved oxygen. No modification to the micelle or protein is necessary, and the topology of both transmembrane and amphipathic helices are readily determined. We apply this method to the measure the topology of a monomeric mutant of phospholamban (AFA-PLN), a 52-residue membrane protein containing both an amphipathic and a transmembrane alpha helix. In dodecylphosphocholine micelles, the amphipathic helix of AFA-PLN was found to have a tilt angle of 87° ± 1° and an average immersion depth of 13.2 Å. The transmembrane helix was found to have an average immersion depth of 5.4 Å, indicating residues 41 and 42 are closest to the micelle centre. The resolution of paramagnetic relaxation rate enhancements from dissolved oxygen compares favourably to those from Ni (II), a hydrophilic paramagnetic species.

  1. CHANGES IN PRODUCTIVITY OF SELECTED BRANCHES OF THE POLISH FOOD SECTOR IN THE YEARS 2004–2013

    Directory of Open Access Journals (Sweden)

    Joanna Baran

    2016-09-01

    Full Text Available The aim of this paper is to specify changes in productivity of the Polish food sector as a whole and its selected branches in the years 2004–2013. Analyses were conducted based on the Malmquist Productivity Index (MPI. In the MPI model the following variables were adopted: the output – sold production (million PLN, inputs – average number of employees (thous and gross value of fi xed assets (million PLN. It was confi rmed that productivity of the Polish food sector improved in the years 2004–2013. Results of analyses showed that changes in technical effi ciency had a greater eff ect on changes in food sector productivity in Poland – particularly in the fi rst period following Poland’s accession to the EU and starting from 2009, i.e. the outbreak of the economic crisis. Technical change had a considerable eff ect on the improvement of productivity in the food sector only in the years 2006– 2008. The greatest mean annual improvement in productivity in the analysed period was observed in meat and milk processing and beverage production

  2. On strategic spatial planning

    Directory of Open Access Journals (Sweden)

    Tošić Branka

    2014-01-01

    Full Text Available The goal of this paper is to explain the origin and development of strategic spatial planning, to show complex features and highlight the differences and/or advantages over traditional, physical spatial planning. Strategic spatial planning is seen as one of approaches in legally defined planning documents, and throughout the display of properties of sectoral national strategies, as well as issues of strategic planning at the local level in Serbia. The strategic approach is clearly recognized at the national and sub-national level of spatial planning in European countries and in our country. It has been confirmed by the goals outlined in documents of the European Union and Serbia that promote the grounds of territorial cohesion and strategic integrated planning, emphasizing cooperation and the principles of sustainable spatial development. [Projekat Ministarstva nauke Republike Srbije, br. 176017

  3. Communication Planning.

    Science.gov (United States)

    Development Communication Report, 1978

    1978-01-01

    Communication planning in developing countries is discussed in individual articles on theory, knowledge production and utilization, planning at the regional level, software, and rural development. A nutrition education project and three experiments in developing educational materials with feedback from villagers in Africa are described in the…

  4. Knowledge-based treatment planning and its potential role in the transition between treatment planning systems.

    Science.gov (United States)

    Masi, Kathryn; Archer, Paul; Jackson, William; Sun, Yilun; Schipper, Matthew; Hamstra, Daniel; Matuszak, Martha

    2017-11-22

    Commissioning a new treatment planning system (TPS) involves many time-consuming tasks. We investigated the role that knowledge-based planning (KBP) can play in aiding a clinic's transition to a new TPS. Sixty clinically treated prostate/prostate bed intensity-modulated radiation therapy (IMRT) plans were exported from an in-house TPS and were used to create a KBP model in a newly implemented commercial application. To determine the benefit that KBP may have in a TPS transition, the model was tested on 2 groups of patients. Group 1 consisted of the first 10 prostate/prostate bed patients treated in the commercial TPS after the transition from the in-house TPS. Group 2 consisted of 10 patients planned in the commercial TPS after 8 months of clinical use. The KBP-generated plan was compared with the clinically used plan in terms of plan quality (ability to meet planning objectives and overall dose metrics) and planning efficiency (time required to generate clinically acceptable plans). The KBP-generated plans provided a significantly improved target coverage (p = 0.01) compared with the clinically used plans for Group 1, but yielded plans of comparable target coverage to the clinically used plans for Group 2. For the organs at risk, the KBP-generated plans produced lower doses, on average, for every normal-tissue objective except for the maximum dose to 0.1 cc of rectum. The time needed for the KBP-generated plans ranged from 6 to 15 minutes compared to 30 to 150 and 15 to 60 minutes for manual planning in Groups 1 and 2, respectively. KBP is a promising tool to aid in the transition to a new TPS. Our study indicates that high-quality treatment plans could have been generated in the newly implemented TPS more efficiently compared with not using KBP. Even after 8 months of the clinical use, KBP still showed an increase in plan quality and planning efficiency compared with manual planning. Copyright © 2017 American Association of Medical Dosimetrists. Published

  5. En Route Descent Advisor Multi-Sector Planning Using Active and Provisional Controller Plans

    Science.gov (United States)

    Vivona, Robert; Green, Steven

    2003-01-01

    As decision support tools are developed to support controllers in complex air traffic control environments, new approaches to maintaining situation awareness and managing traffic planning must be developed to handle the ever-increasing amounts of alerting and advisory data. Within high-density metering and other environments where flight path changes are the rule, not the exception, and where interactions between these changes are required, current trial planning approaches are limited by potential increases in workload. The Enroute Descent Advisor (EDA) is a set of decision support tool capabilities for managing high-density en route traffic subject to metering restrictions. The EDA system s novel approach builds aircraft plans from combinations of user intent data and builds controller plans from combinations of aircraft plans to effectively maintain situation awareness during traffic planning. By maintaining both active (current) and provisional (proposed) controller plans, EDA supports controllers in coordinated traffic planning both within and between sectors. Ultimately, EDA s multi-sector planning approach will facilitate a transition from current sector-oriented operations to a new trajectory-oriented paradigm, enabling new levels of efficiency and collaboration in air traffic control.

  6. Family planning education.

    Science.gov (United States)

    Hamburg, M V

    1983-02-01

    17 days were spent devoted to the effort of learning about China's educational approach to family planning in the hope of discovering how they are achieving their remarkable success in reducing population growth. As a member of the 1981 New York University/SIECUS Colloquim in China, it was necessary to rely on the translation provided by the excellent guides. Discussions were focused on questions prepared in advance about the topics that concerned the group. These observations, based on a short and limited exposure, cover the following areas: marriage and family planning policies; the family planning program; school programs; adult education; family planning workers; and unique aspects of the program. China has an official position on marriage and family planning that continues to undergo revisions. The new marriage law sets the minimum ages of marriage at 22 for men and 20 for women. Almost everyone marries, and an unmarried person over age 28 is a rarity. The family planning program in China is carried out by an extensive organizational network at national, provincial, and local government levels. Officials termed it a "propaganda campaign." Hospitals, clinics, and factories invariably displayed posters; a popular set of four presents the advantages of the 1 child family as follows: late marriage is best, for it allows more time to work and study; 1 child is best for the health of the mother; one gets free medical care for his/her child if a family has only 1 child; and there is more time to teach 1 child. The state operated television regularly explains the 1 child policy utilizing special films. According to 1 family planning official, "before marriage there is little sex." There are few abortions for unmarried women. Education about sex is for adults, for those persons who are about to be married. There is little if any sex education in schools. Sexual teaching is not generally acceptable, especially in the rural areas. By contrast, in Shanghai the physiology

  7. Practical Planning in COLLAGE

    Science.gov (United States)

    Lansky, Amy L.; Getoor, Lise C.; Friedland, Peter (Technical Monitor)

    1994-01-01

    COLLAGE is a domain-independent planner that differs from traditional planners in two key ways: (1) it uses a diverse and extendible set of (it action-based) plan constructions methods; and (2) it utilizes a technique called (it localization) to partition the planning problem into smaller (and potentially interacting) sub problems. In this paper, we describe these features and how they are exploited in two different real-world planning domains. The first domain, building construction planning, has served as a framework for us to investigate how localization can improve scalability. The second domain, data analysis planning, benefits from COLLAGE's unique plan construction and representation methods. In addition, we describe extensions that were necessary to tackle these real-world problems.

  8. Planning Practice and Research

    DEFF Research Database (Denmark)

    2013-01-01

    Urban planning has dramatically shifted when compared with its former logics and styles. Increasingly, the dynamics of large urban agglomerations spanning multiple boundaries put significant pressure on planning institutions to scale up. In this shifting context, how can both planning theory...... and practice co- evolve in adapting to the ever-increasing transformation of cities and urban regions? In this context, Planning Practice and Research (PPR) is seeking perspectives from the young academic community in planning. We propose to publish at least one special edition of PPR with a number of short...... papers from Young Academics. The contributions should address the question of how planning theory and practice can respond to the increasing complexity of cities and regions....

  9. Tax Planning for Enterprises

    Institute of Scientific and Technical Information of China (English)

    Fan Weiqing

    2011-01-01

    @@ Tax planning is legal planning activities for tax savings, meaning tax payers make operation plans within the national policy framework and choose operation programs favorable to tax savings.Along with a maturing socialist market economy system in China, tax planning is becoming an integral part of enterprise management and operation.For a better tax planning, enterprises have to fully understand the meaning, get proficient at relevant strategies, and apply these methods to save taxes and realize the maximization of enterprise value while considering the actual situation.

  10. Systemic Planning

    DEFF Research Database (Denmark)

    Leleur, Steen

    This book presents principles and methodology for planning in a complex world. It sets out a so-called systemic approach to planning, among other things, by applying “hard” and “soft” methodologies and methods in combination. The book is written for Ph.D and graduate students in engineering...

  11. Hanford 300 Area Development Plan

    International Nuclear Information System (INIS)

    Daly, K.S.; Seiler, S.W.; Hail, J.C.

    1991-09-01

    The purpose of the Hanford 300 Area Development Plan (Development Plan) is to guide the physical development of the 300 Area in accordance with US Department of Energy (DOE) Order 4320.1B (DOE 1991b) by performing the following: (1) Establishing a land use plan, setting land use categories that meet the needs of existing and proposed activities; (2) Coordinating existing, 5-yr, and long-range development plans and guiding growth in accordance with those plans; (3) Establishing development guidelines to encourage cost-effective development and minimize conflicts between adjacent activities; (4) Identifying site development issues that need further analysis; Integrating program plans with development plans to ensure a logical progression of development; and, (6) Integrating DOE plans with local agency plans (i.e., city, country, state, and Tri-Cities Science and Technology Park plans)

  12. Contingency planning: preparation of contingency plans

    DEFF Research Database (Denmark)

    Westergaard, J M

    2008-01-01

    . The risk of introducing disease pathogens into a country and the spread of the agent within a country depends on a number of factors including import controls, movement of animals and animal products and the biosecurity applied by livestock producers. An adequate contingency plan is an important instrument...... in the preparation for and the handling of an epidemic. The legislation of the European Union requires that all Member States draw up a contingency plan which specifies the national measures required to maintain a high level of awareness and preparedness and is to be implemented in the event of disease outbreak...

  13. What's an Asthma Action Plan?

    Science.gov (United States)

    ... Educators Search English Español What's an Asthma Action Plan? KidsHealth / For Parents / What's an Asthma Action Plan? ... acción contra el asma? What's an Asthma Action Plan? An asthma action plan (or management plan) is ...

  14. PTTSA Action Plan Report

    International Nuclear Information System (INIS)

    1991-02-01

    The Pre-Tiger Team Self-Assessment (PTTSA) Report identified findings with respect to the way Sandia National Laboratories (SNL), Albuquerque, (including Tonopah Test Range (TTR) and Kauai Test Facility (KTF)) conducts its environment, safety, and health (ES ampersand H) activities. It presented Action Plan Requirements (APR) addressing these findings. The purpose of this PTTSA Action Plan Report is to assist in managing these action plan requirements by collecting, prioritizing, and estimating required resources. The specific objectives addressed by this report include: collection of requirements for the resolution of the findings presented in the PTTSA Report; consolidation of proposed Action Plan Requirements into logical Action Plan groupings for efficiency of resolution; categorization of Action Plans according to severity of the hazards represented by the findings; provision of a basis for long-range planning and issues management; documentation of the status of the proposed corrective actions; establishment of traceability of the corrective action to the original problem or issue; and integration of these plans into the existing ES ampersand H structure. The Action Plans in this report are an intermediate step between the identification of a problem or a finding in the PTTSA Report and the execution of the solution. They consist of requirements for solution, proposed actions, and an estimate of the time and (where applicable) resources required to develop the solution. This report is an input to the process of planning, resource commitment, development, testing, implementation, and maintenance of problem resolution. 2 figs

  15. Single-employer Pension Plans

    Data.gov (United States)

    Pension Benefit Guaranty Corporation — This spreadsheet lists the active single-employer pensions plans insured by PBGC. Plans are identified by name, employer identification number (EIN) and plan number...

  16. 'Plans are useless'.

    Science.gov (United States)

    Bland, Michael

    2013-01-01

    An essential element in crisis recovery is the protection and/or recovery of reputation. This calls for a crisis communications function that is of more than passing interest to the business continuity specialist and which presents two major challenges in this era of process-driven management: (1) it is an inexact science, more about common sense, psychology, empathy and 'playing it by ear' than about box ticking; (2) it does not lend itself to detailed, rigid plans, although some degree of planning is essential. This paper outlines a flexible approach that will help the crisis team to develop a workable communications plan that strikes a balance between being too detailed and too sketchy. It argues that the whole management team should be involved in developing the plan and sets a number of questions, which, on being answered, will help a realistic, achievable and effective plan to evolve.

  17. Transportation Institutional Plan

    Energy Technology Data Exchange (ETDEWEB)

    1986-08-01

    This Institutional Plan is divided into three chapters. Chapter 1 provides background information, discusses the purposes of the Plan and the policy guidance for establishing the transportation system, and describes the projected system and the plans for its integrated development. Chapter 2 discusses the major participants who must interact to build the system. Chapter 3 suggests mechanisms for interaction that will foster wide participation in program planning and implementation and provides a framework for managing and resolving the issues related to development and operation of the transportation system. A list of acronyms and a glossary are included for the reader's convenience. Also included in this Plan are four appendices. Of particular importance is Appendix A, which includes detailed discussion of specific transportation issues. Appendices B, C, and D provide supporting material to assist the reader in understanding the roles of the involved institutions.

  18. SU-D-BRD-04: The Impact of Automatic Radiation Therapy Plan Checks in Treatment Planning

    International Nuclear Information System (INIS)

    Gopan, O; Yang, F; Ford, E

    2015-01-01

    Purpose: The physics plan check verifies various aspects of a treatment plan after dosimetrists have finished creating the plan. Some errors in the plan which are caught by the physics check could be caught earlier in the departmental workflow. The purpose of this project was to evaluate a plan checking script that can be run within the treatment planning system (TPS) by the dosimetrists prior to plan approval and export to the record and verify system. Methods: A script was created in the Pinnacle TPS to automatically check 15 aspects of a plan for clinical practice conformity. The script outputs a list of checks which the plan has passed and a list of checks which the plan has failed so that appropriate adjustments can be made. For this study, the script was run on a total of 108 plans: IMRT (46/108), VMAT (35/108) and SBRT (27/108). Results: Of the plans checked by the script, 77/108 (71%) failed at least one of the fifteen checks. IMRT plans resulted in more failed checks (91%) than VMAT (51%) or SBRT (63%), due to the high failure rate of an IMRT-specific check, which checks that no IMRT segment < 5 MU. The dose grid size and couch removal checks caught errors in 10% and 14% of all plans – errors that ultimately may have resulted in harm to the patient. Conclusion: Approximately three-fourths of the plans being examined contain errors that could be caught by dosimetrists running an automated script embedded in the TPS. The results of this study will improve the departmental workflow by cutting down on the number of plans that, due to these types of errors, necessitate re-planning and re-approval of plans, increase dosimetrist and physician workload and, in urgent cases, inconvenience patients by causing treatment delays

  19. Systems Engineering Management Plan

    International Nuclear Information System (INIS)

    1994-01-01

    The purpose of this Monitored Retrievable Storage (MRS) Project Systems Engineering Management Plan (SEMP) is to define and establish the MRS Project Systems Engineering process that implements the approved policy and requirements of the Office of Civilian Radioactive Waste Management (OCRWM) for the US Department of Energy (DOE). This plan is Volume 5 of the MRS Project Management Plan (PMP). This plan provides the framework for implementation of systems engineering on the MRS Project consistent with DOE Order 4700.1, the OCRWM Program Management System Manual (PMSM), and the OCRWM Systems Engineering Management Plan (SEMP)

  20. Configuration Management Program Plan

    International Nuclear Information System (INIS)

    1991-01-01

    Westinghouse Savannah River Company (WSRC) has established a configuration management (CM) plan to execute the SRS CM Policy and the requirements of the DOE Order 4700.1. The Reactor Restart Division (RRD) has developed its CM Plan under the SRS CM Program and is implementing it via the RRD CM Program Plan and the Integrated Action Plan. The purpose of the RRD CM program is to improve those processes which are essential to the safe and efficient operation of SRS production reactors. This document provides details of this plan

  1. Inspection and test planning

    International Nuclear Information System (INIS)

    Miller, T.

    1980-01-01

    Purpose of Quality Plan - arrangement of all necessary tests or inspections as far as possible filted to certain components or systems. Subject of Quality Plan - precise determination of tests or inspections and - according to the actual safety significance - the certificates to be done. Disposition of Quality Plan - accommodation of tests to the actual state of fabrication. Application of Quality Plan - to any component or system that is regarded. Supervision of Employment - by authorized personnel of manufacturer, customer or authority providing exact employment of quality plan. Overservance of Instructions - certificates given by authorized personnel. (orig./RW)

  2. Fund management plan

    International Nuclear Information System (INIS)

    1984-08-01

    This revision of the Fund Management Plan updates the original plan published in May 1983. It is derived from and supplements the Mission Plan of the Office of Civilian Radioactive Waste Management. A major purpose in preparing this Plan is to inform the public about management of the Nuclear Waste Fund and the Interim Storage Fund. The purpose of the Interim Storage Fund is to finance the provision of the Federal interim storage capacity of up to 1900 metric tons of spent nuclear fuel. The Nuclear Waste Fund is a separate account for all revenues and expenditures related to the geological disposal and monitored retrieval storage of civilian radioactive waste

  3. Public Participation Plan

    International Nuclear Information System (INIS)

    1993-07-01

    The purpose of this Public Participation Plan is to describe the US Department of Energy's (DOE) plan for involving the public in the decision-making process for the Uranium Mill Tailings Remedial Action (UMTRA) Project. The plan describes how the DOE will meet the public participation requirements of the Uranium Mill Tailings Radiation Control Act (UMTRCA) of 1978, as amended, and of the National Environmental Policy Act (NEPA) of 1969. It includes the UMTRA Project Office plans for complying with DOE Order 5440.1D and for implementing the DOE's Public Participation Policy for Environmental Restoration and Waste Management (1992) and Public Participation Guidance for Environmental Restoration and Waste Management (1993)

  4. Ontological Planning

    Directory of Open Access Journals (Sweden)

    Ahmet Alkan

    2017-12-01

    • Is it possible to redefine ontology within the hierarchical structure of planning? We are going to seek answers to some of these questions within the limited scope of this paper and we are going to offer the rest for discussion by just asking them. In light of these assessments, drawing attention, based on ontological knowledge relying on the wholeness of universe, to the question, on macro level planning, of whether or not the ontological realities of man, energy and movements of thinking can provide macro data for planning on a universal level as important factors affecting mankind will be one of the limited objectives of the paper.

  5. Comparison of attitudes related with family planning methods before and after effective family planning counseling.

    Directory of Open Access Journals (Sweden)

    Esra Esim Büyükbayrak

    2010-09-01

    Full Text Available Objective: To evaluate the effect of family planning counseling on the changeover of the family planning method and to determine level of knowledge of participants on family planning methods and their attitude towards changeover of the method after counseling. Setting: Kartal education and reseach hospital obstetrics and gynecology clinic, department of family planning. Patients. 500 consecutive women applying to family planning department for any reason. Interventions: Effective family planning counseling service was given to each participant then a questioner containin 14 questions was applied with face to face technique. Main Outcome Measures: Attitude towards family planning counseling, comparison of the preference of family planning method before and after family planning counseling service and influential sociodemographic parameters on method choise were studied. Results: 45,2% of the participants were not taken family planning counseling service before. knowledge on family planning methods was sufficient in 25,2% of the participants, insufficient in 56,8% of the participants and 18% of the participants reported that they have no idea. 57,8% of the participants change mind about family planning counseling. 52,2% of the participants changeover perious method after counseling. 99,4% of the participants said that family planning counseling service should be given to every women. Preference of family planning method before and after family planning counseling service was statistically significantly different (p<0.01. Educational level, income and age were found to be influential sociodemographic factors for method preference. Conclusions: Effective family planning counseling service is found to have favorable effect on attitude and knowledge about family planning methods. Modern method usage increase as educational level and income of the participants increase.

  6. Planning for What Kind of Teaching? Supporting Cooperating Teachers as Teachers of Planning

    Science.gov (United States)

    Norman, Patricia J.

    2011-01-01

    Planning is a central task of teaching and a central focus in learning to teach. But what does planning entail, and how is planning best learned? What challenges do experienced teachers serving as school-based teacher educators face in becoming teachers of planning? What role can university teacher educators play in helping mentor teachers learn…

  7. Conference Planning.

    Science.gov (United States)

    Carter, Richard

    1982-01-01

    Presents an overview of the management planning technique known as Break Even Analysis and outlines its use as a tool in financial planning for organizations intending to conduct or sponsor a conference, seminar, or workshop. Three figures illustrating Break Even Analysis concepts and a Break Even Analysis worksheet are included. (JL)

  8. Communicative planning as counter-power

    DEFF Research Database (Denmark)

    Elling, Bo

    2017-01-01

    This article presents a theory of communicative planning in which the power of citizens is conceived as a resource in the promotion of long-term planning against the short-term interests of investors in public planning. Its point of departure is the depiction of three planning paradigms – traditi......This article presents a theory of communicative planning in which the power of citizens is conceived as a resource in the promotion of long-term planning against the short-term interests of investors in public planning. Its point of departure is the depiction of three planning paradigms...... – traditional synoptic, incremental and participatory planning – and a critical discussion of different theories within the latter. In the light of this, it is argued that, in practice, planning authorities most often regard public participation as a problem, rather than as a potential. The article dismisses...... this conception and (a) conceptualizes planning on the basis of a Habermasian theory of communicative action and power, (b) shows that the participation of citizens is necessary to secure the inclusion of ethical and aesthetic rationalities in the planning process, and also that (c) citizens may constitute...

  9. SU-E-T-43: A Methodology for Quality Control of IMPT Treatment Plan Based On VMAT Plan

    International Nuclear Information System (INIS)

    Jiang, S; Yang, Y; Liao, L; Wang, X; Li, H; Zhu, X; Zhang, X

    2015-01-01

    Purpose: IMPT plan design is highly dependent on planner’s experiences. VMAT plan design is relatively mature and can even be automated. The quality of IMPT plan designed by in-experienced planner could be inferior to that of VMAT plan designed by experienced planner or automatic planning software. Here we introduce a method for designing IMPT plan based on VMAT plan to ensure the IMPT plan be superior to IMRT/VMAT plan for majority clinical scenario. Methods: To design a new IMPT plan, a VMAT plan is first generated either by experienced planner or by in-house developed automatic planning system. An in-house developed tool is used to generate the dose volume constrains for the IMPT plan as plan template to Eclipse TPS. The beam angles for IMPT plan are selected based on the preferred angles in the VMAT plan. IMPT plan is designed by importing the plan objectives generated from VMAT plan. Majority thoracic IMPT plans are designed using this plan approach in our center. In this work, a thoracic IMPT plan under RTOG 1308 protocol is selected to demonstrate the effectiveness and efficiency of this approach. The dosimetric indices of IMPT are compared with VMAT plan. Results: The PTV D95, lung V20, MLD, mean heart dose, esophagus D1, cord D1 are 70Gy, 31%, 17.8Gy, 25.5Gy, 73Gy, 45Gy for IMPT plan and 65.3Gy, 34%, 21.6Gy, 35Gy, 74Gy, 48Gy for VMAT plan. For majority cases, the high dose region of the normal tissue which is in proximity of PTV is comparable between IMPT and VMAT plan. The low dose region of the IMPT plan is significantly better than VMAT plan. Conclusion: Using the knowledge gained in VMAT plan design can help efficiently and effectively design high quality IMPT plan. The quality of IMPT plan can be controlled to ensure the superiority of IMPT plan compared to VMAT/IMRT plan

  10. SU-E-T-43: A Methodology for Quality Control of IMPT Treatment Plan Based On VMAT Plan

    Energy Technology Data Exchange (ETDEWEB)

    Jiang, S [UT MD Anderson Cancer Center (United States); Tianjin Medical University Cancer Institute and Hospital (China); Yang, Y [UT MD Anderson Cancer Center (United States); Tianjin First Center Hospital (China); Liao, L; Wang, X; Li, H; Zhu, X; Zhang, X [UT MD Anderson Cancer Center (United States)

    2015-06-15

    Purpose: IMPT plan design is highly dependent on planner’s experiences. VMAT plan design is relatively mature and can even be automated. The quality of IMPT plan designed by in-experienced planner could be inferior to that of VMAT plan designed by experienced planner or automatic planning software. Here we introduce a method for designing IMPT plan based on VMAT plan to ensure the IMPT plan be superior to IMRT/VMAT plan for majority clinical scenario. Methods: To design a new IMPT plan, a VMAT plan is first generated either by experienced planner or by in-house developed automatic planning system. An in-house developed tool is used to generate the dose volume constrains for the IMPT plan as plan template to Eclipse TPS. The beam angles for IMPT plan are selected based on the preferred angles in the VMAT plan. IMPT plan is designed by importing the plan objectives generated from VMAT plan. Majority thoracic IMPT plans are designed using this plan approach in our center. In this work, a thoracic IMPT plan under RTOG 1308 protocol is selected to demonstrate the effectiveness and efficiency of this approach. The dosimetric indices of IMPT are compared with VMAT plan. Results: The PTV D95, lung V20, MLD, mean heart dose, esophagus D1, cord D1 are 70Gy, 31%, 17.8Gy, 25.5Gy, 73Gy, 45Gy for IMPT plan and 65.3Gy, 34%, 21.6Gy, 35Gy, 74Gy, 48Gy for VMAT plan. For majority cases, the high dose region of the normal tissue which is in proximity of PTV is comparable between IMPT and VMAT plan. The low dose region of the IMPT plan is significantly better than VMAT plan. Conclusion: Using the knowledge gained in VMAT plan design can help efficiently and effectively design high quality IMPT plan. The quality of IMPT plan can be controlled to ensure the superiority of IMPT plan compared to VMAT/IMRT plan.

  11. Management Planning In Transport

    Directory of Open Access Journals (Sweden)

    Teodor Perić

    2004-07-01

    Full Text Available Management planning in traffic and other activities includesa choice of missions and goals, as well as actions undertakenfor their realisation. It requires decision-making, that is,a choice among alternative trends of future actions. Therefore,planning and control are closely related.There are several types of plans: purposes or missions,goals, strategies, policies, procedures, rules, programs and calculations.Once managers become aware of the opportunities, they rationallyplan the setting of the goals and assumptions about thecurrent and future environment, finding and evaluating alternativetrends, and selecting the one that is to be followed.Therefore, planning means looking ahead and controlmeans looking backwards. The concept of overall planning,thus including traffic planning, illustrates the approach to managementwhich is based on the achieved goals.

  12. Utility planning for decommissioning

    International Nuclear Information System (INIS)

    Williams, D.H.

    1982-01-01

    Though the biggest impact on a utility of nuclear power plant decommissioning may occur many years from now, procrastination of efforts to be prepared for that time is unwarranted. Foresight put into action through planning can significantly affect that impact. Financial planning can assure the recovery of decommissioning costs in a manner equitable to customers. Decision-making planning can minimize adverse affects of current decisions on later decommissioning impacts and prepare a utility to be equipped to make later decommissioning decisions. Technological knowledge base planning can support all other planning aspects for decommissioning and prepare a utility for decommissioning decisions. Informed project planning can ward off potentially significant pitfalls during decommissioning and optimize the effectiveness of the actual decommissioning efforts

  13. Planning Systems for Distributed Operations

    Science.gov (United States)

    Maxwell, Theresa G.

    2002-01-01

    This viewgraph representation presents an overview of the mission planning process involving distributed operations (such as the International Space Station (ISS)) and the computer hardware and software systems needed to support such an effort. Topics considered include: evolution of distributed planning systems, ISS distributed planning, the Payload Planning System (PPS), future developments in distributed planning systems, Request Oriented Scheduling Engine (ROSE) and Next Generation distributed planning systems.

  14. Scenario-based transportation planning with involvement of metropolitan planning organizations.

    Science.gov (United States)

    2009-01-01

    The Office of Virginia's Secretary of Transportation identified 21 transportation policies and 42 performance criteria in Virginia's long-range multimodal transportation plan, VTrans2025. A subsequent planning effort, VTrans2035, provided direction f...

  15. 7 CFR 1207.303 - Plan.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Plan. 1207.303 Section 1207.303 Agriculture... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE POTATO RESEARCH AND PROMOTION PLAN Potato Research and Promotion Plan Definitions § 1207.303 Plan. Plan means this potato research and...

  16. 24 CFR 1003.205 - Eligible planning, urban environmental design and policy-planning-management-capacity building...

    Science.gov (United States)

    2010-04-01

    ... environmental design and policy-planning-management-capacity building activities. 1003.205 Section 1003.205... planning, urban environmental design and policy-planning-management-capacity building activities. (a... plans, general environmental studies, and strategies and action programs to implement plans, including...

  17. The Mission Operations Planning Assistant

    Science.gov (United States)

    Schuetzle, James G.

    1987-01-01

    The Mission Operations Planning Assistant (MOPA) is a knowledge-based system developed to support the planning and scheduling of instrument activities on the Upper Atmospheric Research Satellite (UARS). The MOPA system represents and maintains instrument plans at two levels of abstraction in order to keep plans comprehensible to both UARS Principal Investigators and Command Management personnel. The hierarchical representation of plans also allows MOPA to automatically create detailed instrument activity plans from which spacecraft command loads may be generated. The MOPA system was developed on a Symbolics 3640 computer using the ZetaLisp and ART languages. MOPA's features include a textual and graphical interface for plan inspection and modification, recognition of instrument operational constraint violations during the planning process, and consistency maintenance between the different planning levels. This paper describes the current MOPA system.

  18. Natural Resource Management Plan

    Energy Technology Data Exchange (ETDEWEB)

    Green, T. [Brookhaven National Laboratory (BNL), Upton, NY (United States); Schwager, K. [Brookhaven National Laboratory (BNL), Upton, NY (United States)

    2016-10-01

    This comprehensive Natural Resource Management Plan (NRMP) for Brookhaven National Laboratory (BNL) was built on the successful foundation of the Wildlife Management Plan for BNL, which it replaces. This update to the 2003 plan continues to build on successes and efforts to better understand the ecosystems and natural resources found on the BNL site. The plan establishes the basis for managing the varied natural resources located on the 5,265-acre BNL site, setting goals and actions to achieve those goals. The planning of this document is based on the knowledge and expertise gained over the past 15 years by the Natural Resources management staff at BNL in concert with local natural resource agencies including the New York State Department of Environmental Conservation, Long Island Pine Barrens Joint Planning and Policy Commission, The Nature Conservancy, and others. The development of this plan works toward sound ecological management that not only benefits BNL’s ecosystems but also benefits the greater Pine Barrens habitats in which BNL is situated. This plan applies equally to the Upton Ecological and Research Reserve (Upton Reserve). Any difference in management between the larger BNL area and the Upton Reserve are noted in the text.

  19. US ITER Management Plan

    International Nuclear Information System (INIS)

    1991-12-01

    This US ITER Management Plan is the plan for conducting the Engineering Design Activities within the US. The plan applies to all design, analyses, and associated physics and technology research and development (R ampersand D) required to support the program. The plan defines the management considerations associated with these activities. The plan also defines the management controls that the project participants will follow to establish, implement, monitor, and report these activities. The activities are to be conducted by the project in accordance with this plan. The plan will be updated to reflect the then-current management approach required to meet the project objectives. The plan will be reviewed at least annually for possible revision. Section 2 presents the ITER objectives, a brief description of the ITER concept as developed during the Conceptual Design Activities, and comments on the Engineering Design Activities. Section 3 discusses the planned international organization for the Engineering Design Activities, from which the tasks will flow to the US Home Team. Section 4 describes the US ITER management organization and responsibilities during the Engineering Design Activities. Section 5 describes the project management and control to be used to perform the assigned tasks during the Engineering Design Activities. Section 6 presents the references. Several appendices are provided that contain detailed information related to the front material

  20. Financial planning considerations at retirement.

    Science.gov (United States)

    Cole, R J

    1998-03-01

    The process of retirement planning is a difficult one for a physician. The Planning process should address the areas of Investment Planning, Estate Planning, and Risk Management. This article examines each of these dimensions with special emphasis on Modern Portfolio Theory as the basis for investment planning.

  1. Planning ahead: Improving escalation plans before the weekend.

    Science.gov (United States)

    Zarkali, Angeliki; Black, Duncan; Smee, Elizabeth; Deshraj, Anshul; Smallwood, Nicholas

    2014-01-01

    Handover is the system by which responsibility for patient care is transferred between healthcare professionals. A significant aspect of handover is the existence of an escalation plan for each patient in case of deterioration over the weekend. According to the Royal College of Physicians, all patients should have a clear escalation plan documented in the notes before a weekend, since parent medical teams (Consultant team in charge of care) are best placed to make these decisions. If left to on-call teams, at a time of deterioration over a weekend, they might not have all available information, the patient might be unable to be involved in the decisions, and the family might not be consulted. With this is mind, we decided to analyse the existing handover process in a medium sized district general hospital, with the aim of improving the process and the documentation of escalation plans. The results from our retrospective analysis of the system in place revealed a significant lack of documentation of escalation plans in the medical notes. Three sample wards were selected to analyse the current handover system and test proposed measures before hospital-wide implementation. After trialling of a physical handover meeting in addition to the existing intranet system and a proforma for the Friday ward round, the documentation of escalation plans in the patients' notes improved from 9.1% to 41.1%. Based on these results, as well as formal feedback from junior doctors and informal feedback from other staff, the physical handover meeting and Friday ward round proforma will be implemented throughout the Trust. Our interventions led to an improvement in the documentation of escalation plans in our hospital, thus saving precious time in the event of a patient's deterioration. This also ensures that families and patients are involved in the decision making process and kept informed, and reduces the burden for the weekend on-call teams.

  2. Behavior-based evacuation planning

    KAUST Repository

    Rodriguez, Samuel

    2010-05-01

    In this work, we present a formulation of an evacuation planning problem that is inspired by motion planning and describe an integrated behavioral agent-based and roadmap-based motion planning approach to solve it. Our formulation allows users to test the effect on evacuation of a number of different environmental factors. One of our main focuses is to provide a mechanism to investigate how the interaction between agents influences the resulting evacuation plans. Specifically, we explore how various types of control provided by a set of directing agents effects the overall evacuation planning strategies of the evacuating agents. ©2010 IEEE.

  3. Behavior-based evacuation planning

    KAUST Repository

    Rodriguez, Samuel; Amato, Nancy M

    2010-01-01

    In this work, we present a formulation of an evacuation planning problem that is inspired by motion planning and describe an integrated behavioral agent-based and roadmap-based motion planning approach to solve it. Our formulation allows users to test the effect on evacuation of a number of different environmental factors. One of our main focuses is to provide a mechanism to investigate how the interaction between agents influences the resulting evacuation plans. Specifically, we explore how various types of control provided by a set of directing agents effects the overall evacuation planning strategies of the evacuating agents. ©2010 IEEE.

  4. Disease activity, quality of life and indirect costs of reduced productivity at work, generated by Polish patients with ankylosing spondylitis

    Directory of Open Access Journals (Sweden)

    Paweł Kawalec

    2016-02-01

    Full Text Available Objectives: The aim of the study was to investigate the association between activity of ankylosing spondylitis (AS and decrease in quality of life as well as productivity loss of affected patients in a specified group of patients in the Polish setting. Material and methods : An questionnaire survey was conducted using the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI to assess disease activity, as well as the Work Productivity and Activity Impairment Questionnaires to assess productivity loss; quality of life was presented as utility calculated using the EuroQol 5 questionnaire and also measured on a visual analogue scale (VAS. Indirect costs were assessed with the human capital approach implying gross domestic product per capita or gross value added per worker in Poland in 2014 and were expressed in Polish zlotys (PLN as well as in euros. Correlation was presented using Spearman’s rank correlation coefficient. Results : We performed our analysis based on 78 full questionnaires collected. A mean BASDAI score of 5.91 in the analysed group of patients was detected and mean utility of 0.5135 was observed. Average quality of life measured on the visual analogue scale was 46.55. Mean number of days off work was 45.26 days per year and mean on-the-job productivity loss was 49.29%. Average annual indirect costs per patient were €4241 (17 686 PLN calculated using gross domestic product and €10 172 (42 417 PLN estimated using gross value added. Total productivity loss was significantly correlated with disease activity (strong correlation of 0.6005 and utility (moderate correlation of –0.3698. Conclusions : Ankylosing spondylitis causes a great decrease in quality of life as well as patients’ productivity loss associated with both absenteeism and presenteeism. The greater the disease activity is, the lower is the utility, the lower is the quality of life measured on the VAS, and the greater are the total annual indirect costs. Total

  5. National Waste Terminal Storage Program: information management plan. Volume II. Plan description

    International Nuclear Information System (INIS)

    1977-05-01

    A comprehensive information management plan to provide for the systematic processing of large amounts of internally prepared and externally acquired documentation that will accrue to the Office of Waste Isolation (OWI) during the next decade is outlined. The Information Management Plan of the National Waste Terminal Storage (NWTS) Program is based on time proven procedures developed by government and industry for the requirements determination, acquisition, and the administration of documentation. The NWTS Information Management Plan is designed to establish the basis for the planning, development, implemenation, operation and maintenance of the NWTS Information Management System. This plan will help assure that documentation meets required quality standards and that each organization's needs are reflected when soliciting documentation from subcontractors. An example would be the Quality Assurance documentation requirement necessary to comply with eventual NRC licensing regulations. The provisions of the NWTS Information Management Plan will apply to all documentation from OWI contractors, subcontractors, and suppliers, and to OWI organizations for documentation prepared periodically for external dissemination

  6. Treatment planning for MLC based robotic radiosurgery for brain metastases: plan comparison with circular fields and suggestions for planning strategies

    Directory of Open Access Journals (Sweden)

    Schmitt Daniela

    2017-09-01

    Full Text Available To evaluate the possible range of application of the new InCise2 MLC for the CyberKnife M6 system in brain radiosurgery, a plan comparison was made for 10 brain metastases sized between 1.5 and 9cm3 in 10 patients treated in a single fraction each. The target volumes consist of a PTV derived by expanding the GTV by 1mm and were chosen to have diversity in the cohort regarding regularity of shape, location and the structures needed to be blocked for beam transmission in the vicinity. For each case, two treatment plans were optimized: one using the MLC and one using the IRIS-collimator providing variable circular fields. Plan re-quirements were: dose prescription to the 70% isodose line (18 or 20Gy, 100% GTV coverage, ≥98% PTV coverage, undisturbed central high dose region (95% of maximum dose and a conformity index as low as possible. Plan com-parison parameters were: conformity index (CI, high-dose gradient index (GIH, low-dose gradient index (GIL, total number of monitor units (MU and expected treatment time (TT. For all cases, clinically acceptable plans could be gen-erated with the following results (mean±SD for CI, GIH, GIL, MU and TT, respectively for the MLC plans: 1.09±0.03, 2.77±0.26, 2.61±0.08, 4514±830MU and 27±5min and for the IRIS plans: 1.05±0.01, 3.00±0.35, 2.46±0.08, 8557±1335MU and 42±7min. In summary, the MLC plans were on average less conformal and had a shallower dose gradient in the low dose region, but a steeper dose gradient in the high dose region. This is accompanied by a smaller vol-ume receiving 10Gy. A plan by plan comparison shows that usage of the MLC can spare about one half of the MUs and one third of treatment time. From these experiences and results suggestions for MLC planning strategy can be de-duced.

  7. Environmental Monitoring Plan

    Energy Technology Data Exchange (ETDEWEB)

    Holland, R.C. [Science Applications International Corp., San Diego, CA (United States)

    1993-07-01

    This Environmental Monitoring Plan was written to fulfill the requirements of Department of Energy (DOE) Order 5400.1 and DOE Environmental Regulatory Guide DOE/EH 0173T. This Plan documents the background, organizational structure, and methods used for effluent monitoring and environmental surveillance at Sandia National Laboratories/California. The design, rationale, and historical results of the environmental monitoring system are discussed in detail. Throughout the Plan, recommendations for improvements to the monitoring system are made. This revision to the Environmental Monitoring Plan was written to document the changes made to the Monitoring Program during 1992. Some of the data (most notably the statistical analyses of past monitoring data) has not been changed.

  8. Environmental Implementation Plan

    International Nuclear Information System (INIS)

    1993-01-01

    The purpose of the Environmental Implementation Plan (EIP) is to show the current and future (five years) environmental plans from individual site organizations and divisions, as well as site environmental programs and initiatives which are designed to protect the environment and meet or exceed changing environmental/regulatory requirements. Communicating with site organizations, departments, and committees is essential in making the site's environmental-planning process work. The EIP gives the site the what, when, how, and why for environmental requirements. Through teamwork and proactive planning, a partnership for environmental excellence is formed to achieve the site vision for SRS to become the recognized model for Environmental Excellence in the Department of Energy's Nuclear Weapons Complex

  9. Environmental Implementation Plan

    Energy Technology Data Exchange (ETDEWEB)

    1993-03-15

    The purpose of the Environmental Implementation Plan (EIP) is to show the current and future (five years) environmental plans from individual site organizations and divisions, as well as site environmental programs and initiatives which are designed to protect the environment and meet or exceed changing environmental/regulatory requirements. Communicating with site organizations, departments, and committees is essential in making the site's environmental-planning process work. The EIP gives the site the what, when, how, and why for environmental requirements. Through teamwork and proactive planning, a partnership for environmental excellence is formed to achieve the site vision for SRS to become the recognized model for Environmental Excellence in the Department of Energy's Nuclear Weapons Complex.

  10. Environmental Implementation Plan

    Energy Technology Data Exchange (ETDEWEB)

    1993-03-15

    The purpose of the Environmental Implementation Plan (EIP) is to show the current and future (five years) environmental plans from individual site organizations and divisions, as well as site environmental programs and initiatives which are designed to protect the environment and meet or exceed changing environmental/regulatory requirements. Communicating with site organizations, departments, and committees is essential in making the site`s environmental-planning process work. The EIP gives the site the what, when, how, and why for environmental requirements. Through teamwork and proactive planning, a partnership for environmental excellence is formed to achieve the site vision for SRS to become the recognized model for Environmental Excellence in the Department of Energy`s Nuclear Weapons Complex.

  11. Environmental Monitoring Plan

    International Nuclear Information System (INIS)

    Holland, R.C.

    1993-07-01

    This Environmental Monitoring Plan was written to fulfill the requirements of Department of Energy (DOE) Order 5400.1 and DOE Environmental Regulatory Guide DOE/EH 0173T. This Plan documents the background, organizational structure, and methods used for effluent monitoring and environmental surveillance at Sandia National Laboratories/California. The design, rationale, and historical results of the environmental monitoring system are discussed in detail. Throughout the Plan, recommendations for improvements to the monitoring system are made. This revision to the Environmental Monitoring Plan was written to document the changes made to the Monitoring Program during 1992. Some of the data (most notably the statistical analyses of past monitoring data) has not been changed

  12. Informal Planning in Depopulating Rural Areas : A resource-based view on informal planning practices

    NARCIS (Netherlands)

    Syssner, Josefina; Meijer, M.

    2017-01-01

    Planning research has increasingly recognised that planning in depopulating areas differs from planning in growth areas. Several studies have sought to identify planning theories and strategies that are capable of meeting the challenges presented by depopulating areas. However, most of these studies

  13. Maternal and newborn outcomes in planned home birth vs planned hospital births: a metaanalysis.

    Science.gov (United States)

    Wax, Joseph R; Lucas, F Lee; Lamont, Maryanne; Pinette, Michael G; Cartin, Angelina; Blackstone, Jacquelyn

    2010-09-01

    We sought to systematically review the medical literature on the maternal and newborn safety of planned home vs planned hospital birth. We included English-language peer-reviewed publications from developed Western nations reporting maternal and newborn outcomes by planned delivery location. Outcomes' summary odds ratios with 95% confidence intervals were calculated. Planned home births were associated with fewer maternal interventions including epidural analgesia, electronic fetal heart rate monitoring, episiotomy, and operative delivery. These women were less likely to experience lacerations, hemorrhage, and infections. Neonatal outcomes of planned home births revealed less frequent prematurity, low birthweight, and assisted newborn ventilation. Although planned home and hospital births exhibited similar perinatal mortality rates, planned home births were associated with significantly elevated neonatal mortality rates. Less medical intervention during planned home birth is associated with a tripling of the neonatal mortality rate. Copyright 2010 Mosby, Inc. All rights reserved.

  14. Understanding health insurance plans

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/patientinstructions/000879.htm Understanding health insurance plans To use the sharing features on this ... plan for you and your family. Types of Health Insurance Plans Depending on how you get your health ...

  15. Institutional Plan FY 2001-2005

    Energy Technology Data Exchange (ETDEWEB)

    Chartock, Michael; Hansen, Todd, editors

    2000-07-01

    The FY 2001-2005 Institutional Plan provides an overview of the Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab, the Laboratory) mission, strategic plan, initiatives, and the resources required to fulfill its role in support of national needs in fundamental science and technology, energy resources, and environmental quality. To advance the Department of Energy's ongoing efforts to define the Integrated Laboratory System, the Berkeley Lab Institutional Plan reflects the strategic elements of our planning efforts. The Institutional Plan is a management report that supports the Department of Energy's mission and programs and is an element of the Department of Energy's strategic management planning activities, developed through an annual planning process. The Plan supports the Government Performance and Results Act of 1993 and complements the performance-based contract between the Department of Energy and the Regents of the University of California. It identifies technical and administrative directions in the context of the national energy policy and research needs and the Department of Energy's program planning initiatives. Preparation of the Plan is coordinated by the Office of Planning and Communications from information contributed by Berkeley Lab's scientific and support divisions.

  16. A planning concept incorporating the knowledge of both planning and operations personnel

    Energy Technology Data Exchange (ETDEWEB)

    Valenca, M M; Nepomuceno, L; Teixeira, J C.F.; Santos, Junior, A [Universidade Estadual de Campinas, SP (Brazil)

    1994-12-31

    In this paper, the electrical operation planning problem and the available technological possibilities for the improvement of planner`s work process are analyzed. The importance of the expert`s experience in efficient operation plans production is pointed out. The useful knowledge in planning and operating environments and their automation by Artificial Intelligence techniques are evaluated. Finally, conception of a decision-making support system allowing the interaction of storage expertise with analysis programs proposed, in order to improve the planning process. (author) 15 refs., 4 figs.

  17. Rulison Monitoring Plan

    Energy Technology Data Exchange (ETDEWEB)

    None

    2010-07-01

    The Project Rulison Monitoring Plan has been developed as part of the U.S. Department of Energy (DOE) Office of Legacy Management's mission to protect human health and the environment. The purpose of the plan is to monitor fluids from gas wells for radionuclides that would indicate contamination is migrating from the Rulison detonation zone to producing gas wells, allowing action to be taken before the contamination could pose a risk. The Monitoring Plan (1) lists the contaminants present and identifies those that have the greatest potential to migrate from the detonation zone (radionuclide source term), (2) identifies locations that monitor the most likely transport pathways, (3) identifies which fluids will be sampled (gas and liquid) and why, (4) establishes the frequency of sampling, and (5) specifies the most practical analyses and where the analysis results will be reported. The plan does not affect the long-term hydrologic sampling conducted by DOE since 1972, which will continue for the purpose of sampling shallow groundwater and surface water near the site. The Monitoring Plan was developed in anticipation of gas wells being drilled progressively nearer the Rulison site. DOE sampled 10 gas wells in 1997 and 2005 at distances ranging from 2.7 to 7.6 miles from the site to establish background concentrations for radionuclides. In a separate effort, gas industry operators and the Colorado Oil and Gas Conservation Commission (COGCC) developed an industry sampling and analysis plan that was implemented in 2007. The industry plan requires the sampling of gas wells within 3 miles of the site, with increased requirements for wells within 1 mile of the site. The DOE plan emphasizes the sampling of wells near the site (Figure 1), specifically those with a bottom-hole location of 1 mile or less from the detonation, depending on the direction relative to the natural fracture trend of the producing formation. Studies indicate that even the most mobile

  18. The interventional radiology business plan.

    Science.gov (United States)

    Beheshti, Michael V; Meek, Mary E; Kaufman, John A

    2012-09-01

    Strategic planning and business planning are processes commonly employed by organizations that exist in competitive environments. Although it is difficult to prove a causal relationship between formal strategic/business planning and positive organizational performance, there is broad agreement that formal strategic and business plans are components of successful organizations. The various elements of strategic plans and business plans are not common in the vernacular of practicing physicians. As health care becomes more competitive, familiarity with these tools may grow in importance. Herein we provide an overview of formal strategic and business planning, and offer a roadmap for an interventional radiology-specific plan that may be useful for organizations confronting competitive and financial threats. Copyright © 2012 SIR. Published by Elsevier Inc. All rights reserved.

  19. Robinson Rancheria Strategic Energy Plan; Middletown Rancheria Strategic Energy Plan, Scotts Valley Rancheria Strategic Energy Plan, Elem Indian Colony Strategic Energy Plan, Upperlake Rancheria Strategic Energy Plan, Big Valley Rancheria Strategic Energy Plan

    Energy Technology Data Exchange (ETDEWEB)

    McGinnis and Associates LLC

    2008-08-01

    The Scotts Valley Band of Pomo Indians is located in Lake County in Northern California. Similar to the other five federally recognized Indian Tribes in Lake County participating in this project, Scotts Valley Band of Pomo Indians members are challenged by generally increasing energy costs and undeveloped local energy resources. Currently, Tribal decision makers lack sufficient information to make informed decisions about potential renewable energy resources. To meet this challenge efficiently, the Tribes have committed to the Lake County Tribal Energy Program, a multi Tribal program to be based at the Robinson Rancheria and including The Elem Indian Colony, Big Valley Rancheria, Middletown Rancheria, Habematolel Pomo of Upper Lake and the Scotts Valley Pomo Tribe. The mission of this program is to promote Tribal energy efficiency and create employment opportunities and economic opportunities on Tribal Lands through energy resource and energy efficiency development. This program will establish a comprehensive energy strategic plan for the Tribes based on Tribal specific plans that capture economic and environmental benefits while continuing to respect Tribal cultural practices and traditions. The goal is to understand current and future energy consumption and develop both regional and Tribe specific strategic energy plans, including action plans, to clearly identify the energy options for each Tribe.

  20. Biodiesel Test Plan

    Science.gov (United States)

    2014-07-01

    Biodiesel Test Plan Distribution Statement A: Approved for Public Release; distribution is unlimited. July 2014 Report No. CG-D-07-14...Appendix C) Biodiesel Test Plan ii UNCLAS//Public | CG-926 R&DC | G. W. Johnson, et al. Public | July 2014 N O T I C E This...Development Center 1 Chelsea Street New London, CT 06320 Biodiesel Test Plan iii UNCLAS//Public | CG-926 R&DC | G. W. Johnson, et al

  1. Evaluation of participatory planning: Lessons from Hungarian Natura 2000 management planning processes.

    Science.gov (United States)

    Kovács, Eszter; Kelemen, Eszter; Kiss, Gabriella; Kalóczkai, Ágnes; Fabók, Veronika; Mihók, Barbara; Megyesi, Boldizsár; Pataki, György; Bodorkós, Barbara; Balázs, Bálint; Bela, Györgyi; Margóczi, Katalin; Roboz, Ágnes; Molnár, Dániel

    2017-12-15

    Stakeholder participation in nature conservation policies and especially in the management of protected areas has gained importance in the last decades. These changes are underlined by democratic principles and the perceived contribution of stakeholder involvement to the effectiveness of conservation management. Evaluating participatory processes is essential to learn about the past and thus increase the quality of future processes. The evaluation can be useful for the organisations responsible for planning and management, stakeholders and policy makers as well. The present paper shows the results of a systematic evaluation of 25 participatory processes related to the development of management plans for Natura 2000 sites in Hungary between 2007 and 2015. A conceptual framework was developed to evaluate the process and outcome of participatory management planning processes. Criteria were based on the scientific literature on public participation and tailored to conservation-related management planning and stakeholder involvement. Evaluated processes were grouped in three cases based on their time range and financial sources. Overall, the analysed processes scored at a medium level, showing better performance in the process criteria than in the outcome criteria. The best case scored significantly higher in four criteria compared to the other cases: representativeness, resource availability for facilitation, new, creative ideas and impact on the plan. The main factors behind the success were (1) embeddedness of the planning process in a larger project, where the plan was a tool for conservation, (2) carrying out only one process at a time, (3) previous experience of facilitators and planners with participatory planning and (4) the opportunity and capacity to propose a payment scheme as an incentive. But even this case received low scores in some criteria: conflict resolution, early involvement and well defined goals. Based on the results we suggest that more data is

  2. International benchmark and best practices on national infrastructure plans. Application to Spanish strategic planning

    Energy Technology Data Exchange (ETDEWEB)

    Pino Hernandez, E.M.; Delgado Quiralte, C.

    2016-07-01

    The need for planning regarding investment in infrastructures is recognised and supported by most governments around the world. Planning helps to take effective and correct decisions, provides a basis for monitoring its impacts and also facilitates further developments. However it requires a high level of organization, coordination among stakeholders and anticipation of transport needs. There are some different methodological approaches for strategic planning. This paper examines the importance of infrastructure planning and how it is undertaken in different countries from Europe and other continents. It is based on a benchmarking about planning procedures of 7 reference countries (UK, France, the Netherlands, Poland, Germany, Japan and USA), in addition to others whose strategic plans are being developed at the present moment such as Croatia or Romania. This benchmarking aims to extract and compare best practices carried out in this field and to define the optimal formulation of strategic planning. In this regard, the benchmarking is focused on some key aspects: firstly, on the plan structure and its main contents. There are a lot of differences about how each country defines the future needs for transport and how it establishes the objectives and the strategies to be followed. Secondly, on the characterisation of the authorities which are responsible of the plan development (level of dependence from the government, know-how…) along with the time frame and final validity of the plans. And finally, the level of detail of the proposed actions and budgetary commitments provided by the strategic plans. Throughout the comparative analysis, the knowledge generated by this benchmarking has allowed setting a series of specific recommendations in strategic planning which can be applied as innovative solutions and best practices in future planning processes in Spain. (Author)

  3. Emerging digital plan data – New research perspectives into planning practice and evaluation

    DEFF Research Database (Denmark)

    Fertner, Christian

    Profound digitalization in public administration in many European countries is gaining momentum and spatial planning is no exception. International policies as e.g. EU’s INSPIRE directive from 2007, EU’s strategy for a digital single market or also the Arctic SDI Strategy from 2015 are driving......) planning databases and portals. Denmark is one of the forerunners in that digitalization, e.g. with its digital plan platform “plandata.dk” which, since 2006, collects all regional, municipal and local plans in a geodatabase. This includes e.g. over 33,000 local plans which are currently effective...

  4. Countywide Evaluation of the Long-Term Family Self-Sufficiency Plan. Assessing the Utility of the LTFSS Plan Service Delivery and Planning Framework

    National Research Council Canada - National Science Library

    Davis, Lois

    2002-01-01

    ...) is the lead agency responsible for implementing the evaluation of the LTFSS Plan. On December 5, 2000, the Board approved the implementation plan for the evaluation of the LTFSS Plan, LTFSS Project #46...

  5. Energy Efficiency Plan 2009-2012; Energie Efficiency Plan 2009-2012

    Energy Technology Data Exchange (ETDEWEB)

    Meulen, M.M.W. (ed.)

    2009-02-15

    The aim of the Energy Efficiency Plan is to give an overview of the energy conservation plans of the Eindhoven University of Technology in Eindhoven, Netherlands, which must result in efficient use of energy conform the long-range agreements between businesses, industry and organizations and the Dutch government to improve energy efficiency (MJA3) [Dutch] Het doel van het EEP (Energie Efficiency Plan) is het in beeld brengen van de energiebesparingsplannen die leiden tot een efficienter gebruik van energie conform de MJA-3 afspraak (de derde Meerjaren Afspraak)

  6. Family planning management for the migrant population in sending areas. Urban family planning programme.

    Science.gov (United States)

    1997-02-01

    This brief article was adapted from a report by the Longchang County Government, Sichuan Province, China, at the National Conference on Urban Family Planning Programs. The Longchang County family planning program has shifted emphasis since 1990 toward management of out-migrant workers. Overpopulation in the family planning region resulted in each person having about one-sixth of an acre (0.6 mu) of land. There were about 200,000 surplus rural workers. 75,000 migrants left the region in 1995, of which 70,300 had signed birth control contracts and had received family planning certificates. Family planning township agencies in Longchang County increased their IEC and counseling services for migrants and their families. The Longchang County family planning program maintained family planning contacts in receiving areas in order to obtain pregnancy and birth information on the migrant population. During 1991-95 the number of unplanned births declined from 1394 to 71, and 97% of the births were planned.

  7. Developing nursing care plans.

    Science.gov (United States)

    Ballantyne, Helen

    2016-02-24

    This article aims to enhance nurses' understanding of nursing care plans, reflecting on the past, present and future use of care planning. This involves consideration of the central theories of nursing and discussion of nursing models and the nursing process. An explanation is provided of how theories of nursing may be applied to care planning, in combination with clinical assessment tools, to ensure that care plans are context specific and patient centred.

  8. Sport event marketing plan

    Directory of Open Access Journals (Sweden)

    Gašović Milan

    2007-01-01

    Full Text Available A marketing plan details how an event organization will compete in the marketplace in terms of its service offerings, promotions and evaluation. During the first stage of the marketing plan process, a number of its consumers (current, former and prospective and competitors. Marketing objectives are developed and implemented using an action plan. The marketing plan objectives are evaluated using an objective-discrepancy approach to determine the extent to which they were attained.

  9. Integrating design and production planning with knowledge-based inspection planning system

    International Nuclear Information System (INIS)

    Abbasi, Ghaleb Y.; Ketan, Hussein S.; Adil, Mazen B.

    2005-01-01

    In this paper an intelligent environment to integrate design and inspection earlier to the design stage. A hybrid knowledge-based approach integrating computer-aided design (CAD) and computer-aided inspection planning (CAIP) was developed, thereafter called computer-aided design and inspection planning (CADIP). CADIP was adopted for automated dimensional inspection planning. Critical functional features were screened based on certain attributes for part features for inspection planning application. Testing the model resulted in minimizing the number of probing vectors associated with the most important features in the inspected prismatic part, significant reduction in inspection costs and release of human labor. In totality, this tends to increase customer satisfaction as a final goal of the developed system. (author)

  10. Strategic planning--a plan for excellence for South Haven Health System.

    Science.gov (United States)

    Urbanski, Joanne; Baskel, Maureen; Martelli, Mary

    2011-01-01

    South Haven Health System has developed an innovative approach to strategic planning. The key to success of this process has been the multidisciplinary involvement of all stakeholders from the first planning session through the final formation of a strategic plan with measurable objectives for each goal. The process utilizes a Conversation Café method for identifying opportunities and establishing goals, Strategic Oversight Teams to address each goal and a Champion for implementation of each objective. Progress is measured quarterly by Strategic Oversight Team report cards. Transparency of communication within the organization and the sharing of information move the plan forward. The feedback from participant evaluations has been overwhelmingly positive. They are involved and excited.

  11. TECHNOLOGICAL IMPLEMENTATION PLAN

    DEFF Research Database (Denmark)

    Bellini, Anna

    2004-01-01

    This document has the purpose to describe the technological implementation plan in the IDEAL project.......This document has the purpose to describe the technological implementation plan in the IDEAL project....

  12. Wilderness fire management planning guide

    Science.gov (United States)

    William C. Fischer

    1984-01-01

    Outlines a procedure for fire management planning for parks; wilderness areas; and other wild, natural, or essentially undeveloped areas. Discusses background and philosophy of wilderness fire management, planning concepts, planning elements, and planning methods.

  13. Making a Quit Plan

    Science.gov (United States)

    ... BACK CLOSE SMOKEFREE.GOV HOME Create My Quit Plan Quitting starts now. Make a plan . Step 1 of 7 mark Step 2 of ... boosts your chances of success. Build a quit plan to get ready and find out what to ...

  14. Space Station Freedom operations planning

    Science.gov (United States)

    Accola, Anne L.; Keith, Bryant

    1989-01-01

    The Space Station Freedom program is developing an operations planning structure which assigns responsibility for planning activities to three tiers of management. The strategic level develops the policy, goals and requirements for the program over a five-year horizon. Planning at the tactical level emphasizes program integration and planning for a two-year horizon. The tactical planning process, architecture, and products have been documented and discussed with the international partners. Tactical planning includes the assignment of user and system hardware as well as significant operational events to a time increment (the period of time from the arrival of one Shuttle to the manned base to the arrival of the next). Execution-level planning emphasizes implementation, and each organization produces detailed plans, by increment, that are specific to its function.

  15. A Planning Palimpsest

    DEFF Research Database (Denmark)

    Carter, Helen Frances Lindsay; Gutzon Larsen, Henrik; Olesen, Kristian

    2015-01-01

    In this article, we analyse the evolution and transformation of Danish spatial planning from its tentative origins in liberalist politics, through its rise as a central feature of the welfare state project, to its more recent entrepreneurial forms in a context of neoliberalisation. The article...... demonstrates how transformations of Danish spatial planning discourses and practices must be understood in context of previous discourses and practices sedimented as layers of meaning and materiality through time and over space. These layers do not completely overlay one another, but present a palimpsest...... saturated with contradictions as well as possibilities. We propose the notion of the ‘planning palimpsest’ as a helpful metaphor for drawing attention to the historical-geographical characteristics of planning discourses and practices....

  16. Curative procedures of oral health and structural characteristics of primary dental care.

    Science.gov (United States)

    Baumgarten, Alexandre; Hugo, Fernando Neves; Bulgarelli, Alexandre Fávero; Hilgert, Juliana Balbinot

    2018-04-09

    To evaluate if the provision of clinical dental care, by means of the main curative procedures recommended in Primary Health Care, is associated with team structural characteristics, considering the presence of a minimum set of equipment, instrument, and supplies in Brazil's primary health care services. A cross-sectional exploratory study based on data collected from 18,114 primary healthcare services with dental health teams in Brazil, in 2014. The outcome was created from the confirmation of five clinical procedures performed by the dentist, accounting for the presence of minimum equipment, instrument, and supplies to carry them out. Covariables were related to structural characteristics. Poisson regression with robust variance was used to obtain crude and adjusted prevalence ratios, with 95% confidence intervals. A total of 1,190 (6.5%) dental health teams did not present the minimum equipment to provide clinical dental care and only 2,498 (14.8%) had all the instrument and supplies needed and provided the five curative procedures assessed. There was a positive association between the outcome and the composition of dental health teams, higher workload, performing analysis of health condition, and monitoring of oral health indicators. Additionally, the dental health teams that planned and programmed oral health actions with the primary care team monthly provided the procedures more frequently. Dentists with better employment status, career plans, graduation in public health or those who underwent permanent education activities provided the procedures more frequently. A relevant number of Primary Health Care services did not have the infrastructure to provide clinical dental care. However, better results were found in dental health teams with oral health technicians, with higher workload and that plan their activities, as well as in those that employed dentists with better working relationships, who had dentists with degrees in public health and who underwent

  17. Curative procedures of oral health and structural characteristics of primary dental care

    Directory of Open Access Journals (Sweden)

    Alexandre Baumgarten

    2018-04-01

    Full Text Available ABSTRACT OBJECTIVE To evaluate if the provision of clinical dental care, by means of the main curative procedures recommended in Primary Health Care, is associated with team structural characteristics, considering the presence of a minimum set of equipment, instrument, and supplies in Brazil’s primary health care services. METHODS A cross-sectional exploratory study based on data collected from 18,114 primary healthcare services with dental health teams in Brazil, in 2014. The outcome was created from the confirmation of five clinical procedures performed by the dentist, accounting for the presence of minimum equipment, instrument, and supplies to carry them out. Covariables were related to structural characteristics. Poisson regression with robust variance was used to obtain crude and adjusted prevalence ratios, with 95% confidence intervals. RESULTS A total of 1,190 (6.5% dental health teams did not present the minimum equipment to provide clinical dental care and only 2,498 (14.8% had all the instrument and supplies needed and provided the five curative procedures assessed. There was a positive association between the outcome and the composition of dental health teams, higher workload, performing analysis of health condition, and monitoring of oral health indicators. Additionally, the dental health teams that planned and programmed oral health actions with the primary care team monthly provided the procedures more frequently. Dentists with better employment status, career plans, graduation in public health or those who underwent permanent education activities provided the procedures more frequently. CONCLUSIONS A relevant number of Primary Health Care services did not have the infrastructure to provide clinical dental care. However, better results were found in dental health teams with oral health technicians, with higher workload and that plan their activities, as well as in those that employed dentists with better working relationships

  18. Curative procedures of oral health and structural characteristics of primary dental care

    Science.gov (United States)

    Baumgarten, Alexandre; Hugo, Fernando Neves; Bulgarelli, Alexandre Fávero; Hilgert, Juliana Balbinot

    2018-01-01

    ABSTRACT OBJECTIVE To evaluate if the provision of clinical dental care, by means of the main curative procedures recommended in Primary Health Care, is associated with team structural characteristics, considering the presence of a minimum set of equipment, instrument, and supplies in Brazil’s primary health care services. METHODS A cross-sectional exploratory study based on data collected from 18,114 primary healthcare services with dental health teams in Brazil, in 2014. The outcome was created from the confirmation of five clinical procedures performed by the dentist, accounting for the presence of minimum equipment, instrument, and supplies to carry them out. Covariables were related to structural characteristics. Poisson regression with robust variance was used to obtain crude and adjusted prevalence ratios, with 95% confidence intervals. RESULTS A total of 1,190 (6.5%) dental health teams did not present the minimum equipment to provide clinical dental care and only 2,498 (14.8%) had all the instrument and supplies needed and provided the five curative procedures assessed. There was a positive association between the outcome and the composition of dental health teams, higher workload, performing analysis of health condition, and monitoring of oral health indicators. Additionally, the dental health teams that planned and programmed oral health actions with the primary care team monthly provided the procedures more frequently. Dentists with better employment status, career plans, graduation in public health or those who underwent permanent education activities provided the procedures more frequently. CONCLUSIONS A relevant number of Primary Health Care services did not have the infrastructure to provide clinical dental care. However, better results were found in dental health teams with oral health technicians, with higher workload and that plan their activities, as well as in those that employed dentists with better working relationships, who had dentists

  19. 26 CFR 1.381(c)(11)-1 - Contributions to pension plan, employees' annuity plans, and stock bonus and profit-sharing plans.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 4 2010-04-01 2010-04-01 false Contributions to pension plan, employees... TAXES Insolvency Reorganizations § 1.381(c)(11)-1 Contributions to pension plan, employees' annuity... or transferor corporation in respect of any pension, annuity, stock bonus, or profit-sharing plan. (b...

  20. Regional manpower planning

    OpenAIRE

    G. Erens; P. Salamink; C.A. Van der Merwe CA

    2003-01-01

    Particular problems come to the fore when planning development at the regional level. These range from the complexities of the multifarious interactions between the sect oral and local components of the region to the necessity of achieving extensive participation of regional stakeholders in the planning process. In this paper a methodology for regional manpower planning is proposed. The methodology is designed to accommodate the full range of problems by applying a systems approach which is b...

  1. Improving IMRT-plan quality with MLC leaf position refinement post plan optimization

    International Nuclear Information System (INIS)

    Niu Ying; Zhang Guowei; Berman, Barry L.; Parke, William C.; Yi Byongyong; Yu, Cedric X.

    2012-01-01

    Purpose: In intensity-modulated radiation therapy (IMRT) planning, reducing the pencil-beam size may lead to a significant improvement in dose conformity, but also increase the time needed for the dose calculation and plan optimization. The authors develop and evaluate a postoptimization refinement (POpR) method, which makes fine adjustments to the multileaf collimator (MLC) leaf positions after plan optimization, enhancing the spatial precision and improving the plan quality without a significant impact on the computational burden. Methods: The authors’ POpR method is implemented using a commercial treatment planning system based on direct aperture optimization. After an IMRT plan is optimized using pencil beams with regular pencil-beam step size, a greedy search is conducted by looping through all of the involved MLC leaves to see if moving the MLC leaf in or out by half of a pencil-beam step size will improve the objective function value. The half-sized pencil beams, which are used for updating dose distribution in the greedy search, are derived from the existing full-sized pencil beams without need for further pencil-beam dose calculations. A benchmark phantom case and a head-and-neck (HN) case are studied for testing the authors’ POpR method. Results: Using a benchmark phantom and a HN case, the authors have verified that their POpR method can be an efficient technique in the IMRT planning process. Effectiveness of POpR is confirmed by noting significant improvements in objective function values. Dosimetric benefits of POpR are comparable to those of using a finer pencil-beam size from the optimization start, but with far less computation and time. Conclusions: The POpR is a feasible and practical method to significantly improve IMRT-plan quality without compromising the planning efficiency.

  2. SBNCT plan: A 3-dimensional treatment planning system for boron neutron capture therapy

    International Nuclear Information System (INIS)

    Reinstein, L.E.; Ramsay, E.B.; Gajewski, J.; Ramamoorthy, S.; Meek, A.G.

    1993-01-01

    The need for accurate and comprehensive 3-dimensional treatment planning for boron neutron capture therapy (BNCT) has been debated for the past several years. Although many argue against the need for elaborate and expensive treatment planning programs which mimic conventional radiotherapy planning systems, it is clear that in order to realize significant gains over conventional fractionated radiation therapy, patients must be treated to the edge of normal tissue tolerance. Just how close to this edge is dictated by the uncertainties in dosimetry. Hence the focus of BNCT planning is the determination of dose distribution throughout normal tissue volumes. Although precise geometric manipulation of the epithermal neutron beam is not achievable, the following variables play an important role in BNCT optimization: patient orientation, dose fractionation, number of fields, megawatt-minutes per fraction, use of surface bolus, and use of collimation. Other variables which are not as easily adjustable and would not, therefore, be part of treatment planning optimization, include external patient contour, internal patient heterogeneities, boron compound distributions, and RBE's. The boron neutron capture therapy planning system developed at SUNY Stony Brook (SBNCT-Plan) was designed as an interactive graphic tool to assist the radiation oncologist in generating the optimum plan for a neutron capture treatment

  3. Influenza pandemic planning guide

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-11-15

    An influenza pandemic will have serious economic impacts on the natural gas industry due to absenteeism as well as downstream effects due to supply disruption.This guide was prepared to assist gas distribution companies in planning for an influenza epidemic. The guide aimed to minimize the risks that an influenza pandemic might pose to the health and safety of employees and the continuity of business operations. The guide discussed 5 critical aspects of emergency planning: (1) prevention and threat mitigation; (2) preparedness; (3) response; (4) business continuity; and (5) communication. The legal context of the emergency plans were discussed. The plans were also discussed to other essential infrastructure emergency response plans. Recommendations were presented for infection control, decentralization and access restriction. Outlines for pandemic response planning teams and training and exercise programs were provided. Issues related to alert, mobilization, and response procedures were also discussed. 10 refs., 3 tabs., 1 fig.

  4. Language Planning: Corpus Planning.

    Science.gov (United States)

    Baldauf, Richard B., Jr.

    1989-01-01

    Focuses on the historical and sociolinguistic studies that illuminate corpus planning processes. These processes are broken down and discussed under two categories: those related to the establishment of norms, referred to as codification, and those related to the extension of the linguistic functions of language, referred to as elaboration. (60…

  5. Dynamics in self-regulation : Plan execution self-efficacy and mastery of action plans

    OpenAIRE

    Scholz, Urte; Sniehotta, Falco F.; Schüz, Benjamin; Oeberst, Andries

    2007-01-01

    This study investigated whether an individual's plan execution self-efficacy precedes mastery of the respective action plan or vice versa. Study participants were 122 cardiac rehabilitation patients. Plan execution self-efficacy and mastery of a personal action plan on physical activity were assessed each week for 6 weeks after discharge from rehabilitation. Physical exercise was assessed 2 months after discharge. Multilevel cross-lagged panel analyses resulted in a positive effect of mastery...

  6. A novel implementation of mARC treatment for non-dedicated planning systems using converted IMRT plans

    International Nuclear Information System (INIS)

    Dzierma, Yvonne; Nuesken, Frank; Licht, Norbert; Ruebe, Christian

    2013-01-01

    The modulated arc (mARC) technique has recently been introduced by Siemens as an analogue to VMAT treatment. However, up to now only one certified treatment planning system supports mARC planning. We therefore present a conversion algorithm capable of converting IMRT plans created by any treatment planning system into mARC plans, with the hope of expanding the availability of mARC to a larger range of clinical users and researchers. As additional advantages, our implementation offers improved functionality for planning hybrid arcs and provides an equivalent step-and-shoot plan for each mARC plan, which can be used as a back-up concept in institutions where only one linac is equipped with mARC. We present a feasibility study to outline a practical implementation of mARC plan conversion using Philips Pinnacle and Prowess Panther. We present examples for three different kinds of prostate and head-and-neck plans, for 6 MV and flattening-filter-free (FFF) 7 MV photon energies, which are dosimetrically verified. It is generally more difficult to create good quality IMRT plans in Pinnacle using a large number of beams and few segments. We present different ways of optimization as examples. By careful choosing the beam and segment arrangement and inversion objectives, we achieve plan qualities similar to our usual IMRT plans. The conversion of the plans to mARC format yields functional plans, which can be irradiated without incidences. Absolute dosimetric verification of both the step-and-shoot and mARC plans by point dose measurements showed deviations below 5% local dose, mARC plans deviated from step-and-shoot plans by no more than 1%. The agreement between GafChromic film measurements of planar dose before and after mARC conversion is excellent. The comparison of the 3D dose distribution measured by PTW Octavius 729 2D-Array with the step-and-shoot plans and with the TPS is well above the pass criteria of 90% of the points falling within 5% local dose and 3 mm distance

  7. Emergency plan belgian experience

    International Nuclear Information System (INIS)

    Clymans, A.

    1989-01-01

    The Chernobyl disaster prompted authorities in Belgium to carry out a comprehensive review of all emergency plans and, in particular, those designed specifically for nuclear accidents. This review was aimed at determining what type of plans existed and to what extent such plans were operational. This paper sets out to present a broad overview of different aspects of this problem: organization of public emergency plans, co-ordination of operations, merits and demerits of centralization as opposed to decentralization, planning zones, obligation to release information to the public and relations with the media, and finally the international dimension to the problem. The author expresses the hope that the latter area will inspire practical suggestions [fr

  8. Project Management Plan Solution Stabilization

    International Nuclear Information System (INIS)

    SATO, P.K.

    1999-01-01

    This plan presents the overall objectives, description, justification and planning for the Plutonium Finishing Plant (PFP) Solutions Stabilization subproject. The intent of this plan is to describe how this project will be managed and integrated with other facility stabilization and deactivation activities. This plan supplements the overall integrated plan presented in the Integrated Project Management Plan (IPMP) for the Plutonium Finishing Plant Stabilization and Deactivation Project, HNF-3617. This project plan is the top-level definitive project management document for the PFP Solution Stabilization subproject. It specifies the technical, schedule, requirements and the cost baselines to manage the execution of the Solution Stabilization subproject. Any deviations to the document must be authorized through the appropriate change control process

  9. Project Management Plan Solution Stabilization

    Energy Technology Data Exchange (ETDEWEB)

    SATO, P.K.

    1999-08-31

    This plan presents the overall objectives, description, justification and planning for the Plutonium Finishing Plant (PFP) Solutions Stabilization subproject. The intent of this plan is to describe how this project will be managed and integrated with other facility stabilization and deactivation activities. This plan supplements the overall integrated plan presented in the Integrated Project Management Plan (IPMP) for the Plutonium Finishing Plant Stabilization and Deactivation Project, HNF-3617. This project plan is the top-level definitive project management document for the PFP Solution Stabilization subproject. It specifies the technical, schedule, requirements and the cost baselines to manage the execution of the Solution Stabilization subproject. Any deviations to the document must be authorized through the appropriate change control process.

  10. Person-Centered Transition Planning.

    Science.gov (United States)

    Miner, Craig A.; Bates, Paul E.

    1997-01-01

    Describes a person-centered planning approach for involving students with disabilities and their families in the transition planning process. Components of person-centered planning are discussed, including development of a personal profile, identification of future lifestyle preferences, action steps and responsible parties, and necessary changes…

  11. NACS Store Planning Manual.

    Science.gov (United States)

    College Store Journal, 1979

    1979-01-01

    Topics discussed by the NACS Store Planning/Renovation Committees in this updated version of the college store renovation manual include: short- and long-range planning, financial considerations, professional planning assistance, the store's image and business character, location considerations, building requirements, space requirements, fixtures,…

  12. Influence of increment of gantry angle and number of arcs on esophageal volumetric modulated arc therapy planning in Monaco planning system: A planning study

    Directory of Open Access Journals (Sweden)

    L Nithya

    2014-01-01

    Full Text Available The objective of this study was to analyze the influence of the increment of gantry angle and the number of arcs on esophageal volumetric modulated arc therapy plan. All plans were done in Monaco planning system for Elekta Synergy linear accelerator with 80 multileaf collimator (MLC. Volumetric modulated arc therapy (VMAT plans were done with different increment of gantry angle like 15 o , 20 o , 30 o and 40 o . The remaining parameters were similar for all the plans. The results were compared. To compare the plan quality with number of arcs, VMAT plans were done with single and dual arc with increment of gantry angle of 20 o . The dose to gross tumor volume (GTV for 60 Gy and planning target volume (PTV for 48 Gy was compared. The dosimetric parameters D 98% , D 95% , D 50% and D max of GTV were analyzed. The homogeneity index (HI and conformity index (CI of GTV were studied and the dose to 98% and 95% of PTV was analyzed. Maximum dose to spinal cord and planning risk volume of cord (PRV cord was compared. The Volume of lung receiving 10 Gy, 20 Gy and mean dose was analyzed. The volume of heart receiving 30 Gy and 45 Gy was compared. The volume of normal tissue receiving greater than 2 Gy and 5 Gy was compared. The number of monitor units (MU required to deliver the plans were compared. The plan with larger increment of gantry angle proved to be superior to smaller increment of gantry angle plans in terms of dose coverage, HI, CI and normal tissue sparing. The number of arcs did not make any difference in the quality of the plan.

  13. Feasibility of identification of gamma knife planning strategies by identification of pareto optimal gamma knife plans.

    Science.gov (United States)

    Giller, C A

    2011-12-01

    The use of conformity indices to optimize Gamma Knife planning is common, but does not address important tradeoffs between dose to tumor and normal tissue. Pareto analysis has been used for this purpose in other applications, but not for Gamma Knife (GK) planning. The goal of this work is to use computer models to show that Pareto analysis may be feasible for GK planning to identify dosimetric tradeoffs. We define a GK plan A to be Pareto dominant to B if the prescription isodose volume of A covers more tumor but not more normal tissue than B, or if A covers less normal tissue but not less tumor than B. A plan is Pareto optimal if it is not dominated by any other plan. Two different Pareto optimal plans represent different tradeoffs between dose to tumor and normal tissue, because neither plan dominates the other. 'GK simulator' software calculated dose distributions for GK plans, and was called repetitively by a genetic algorithm to calculate Pareto dominant plans. Three irregular tumor shapes were tested in 17 trials using various combinations of shots. The mean number of Pareto dominant plans/trial was 59 ± 17 (sd). Different planning strategies were identified by large differences in shot positions, and 70 of the 153 coordinate plots (46%) showed differences of 5mm or more. The Pareto dominant plans dominated other nearby plans. Pareto dominant plans represent different dosimetric tradeoffs and can be systematically calculated using genetic algorithms. Automatic identification of non-intuitive planning strategies may be feasible with these methods.

  14. Multicriteria optimization informed VMAT planning

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Huixiao; Craft, David L.; Gierga, David P., E-mail: dgierga@partners.org

    2014-04-01

    We developed a patient-specific volumetric-modulated arc therapy (VMAT) optimization procedure using dose-volume histogram (DVH) information from multicriteria optimization (MCO) of intensity-modulated radiotherapy (IMRT) plans. The study included 10 patients with prostate cancer undergoing standard fractionation treatment, 10 patients with prostate cancer undergoing hypofractionation treatment, and 5 patients with head/neck cancer. MCO-IMRT plans using 20 and 7 treatment fields were generated for each patient on the RayStation treatment planning system (clinical version 2.5, RaySearch Laboratories, Stockholm, Sweden). The resulting DVH of the 20-field MCO-IMRT plan for each patient was used as the reference DVH, and the extracted point values of the resulting DVH of the MCO-IMRT plan were used as objectives and constraints for VMAT optimization. Weights of objectives or constraints of VMAT optimization or both were further tuned to generate the best match with the reference DVH of the MCO-IMRT plan. The final optimal VMAT plan quality was evaluated by comparison with MCO-IMRT plans based on homogeneity index, conformity number of planning target volume, and organ at risk sparing. The influence of gantry spacing, arc number, and delivery time on VMAT plan quality for different tumor sites was also evaluated. The resulting VMAT plan quality essentially matched the 20-field MCO-IMRT plan but with a shorter delivery time and less monitor units. VMAT plan quality of head/neck cancer cases improved using dual arcs whereas prostate cases did not. VMAT plan quality was improved by fine gantry spacing of 2 for the head/neck cancer cases and the hypofractionation-treated prostate cancer cases but not for the standard fractionation–treated prostate cancer cases. MCO-informed VMAT optimization is a useful and valuable way to generate patient-specific optimal VMAT plans, though modification of the weights of objectives or constraints extracted from resulting DVH of MCO

  15. Environmental monitoring plan

    International Nuclear Information System (INIS)

    Holland, R.C.

    1997-02-01

    This Environmental Monitoring Plan was written to fulfill the requirements of Department of Energy (DOE) Order 5400.1 and DOE Environmental Regulatory Guide DOE/EH 0173T. This Plan documents the background, organizational structure, and methods used for effluent monitoring and environmental surveillance at Sandia National Laboratories/California. The design, rationale, and historical results of the environmental monitoring system are discussed in detail. Throughout the Plan, recommendations for improvements to the monitoring system are made. 52 refs., 10 figs., 12 tabs

  16. Planning for exercises of the Federal Radiological Monitoring and Assessment Plan

    International Nuclear Information System (INIS)

    Adler, M.V.

    1985-11-01

    This report is to be used in planning radiological emergency exercises to test the Federal Radiological Monitoring and Assessment Plan (FRMAP). Although developed for this specific purpose, the document also contains material that may be useful for planning other types of exercises. This report describes the types of exercises that might be used, the steps in planning and conducting the exercises, and the special considerations required for exercises to test the FRMAP. FRMAP exercises typically involve several federal and state agencies. General and specific objectives that could guide these exercises, as well as the possible activities of all the participants - players, controllers, and evaluators - are discussed. The resources that each participating federal agency might provide during an exercise are listed

  17. Complexity Results in Epistemic Planning

    DEFF Research Database (Denmark)

    Bolander, Thomas; Jensen, Martin Holm; Schwarzentruber, Francois

    2015-01-01

    Epistemic planning is a very expressive framework that extends automated planning by the incorporation of dynamic epistemic logic (DEL). We provide complexity results on the plan existence problem for multi-agent planning tasks, focusing on purely epistemic actions with propositional preconditions...

  18. Is it possible for knowledge-based planning to improve intensity modulated radiation therapy plan quality for planners with different planning experiences in left-sided breast cancer patients?

    Science.gov (United States)

    Wang, Juanqi; Hu, Weigang; Yang, Zhaozhi; Chen, Xiaohui; Wu, Zhiqiang; Yu, Xiaoli; Guo, Xiaomao; Lu, Saiquan; Li, Kaixuan; Yu, Gongyi

    2017-05-22

    Knowledge-based planning (KBP) is a promising technique that can improve plan quality and increase planning efficiency. However, no attempts have been made to extend the domain of KBP for planners with different planning experiences so far. The purpose of this study was to quantify the potential gains for planners with different planning experiences after implementing KBP in intensity modulated radiation therapy (IMRT) plans for left-sided breast cancer patients. The model libraries were populated with 80 expert clinical plans from treated patients who previously received left-sided breast-conserving surgery and IMRT with simultaneously integrated boost. The libraries were created on the RapidPlan TM . 6 planners with different planning experiences (2 beginner planners, 2 junior planners and 2 senior planners) generated manual and KBP optimized plans for additional 10 patients, similar to those included in the model libraries. The plan qualities were compared between manual and KBP plans. All plans were capable of achieving the prescription requirement. There were almost no statistically significant differences in terms of the planning target volume (PTV) coverage and dose conformality. It was demonstrated that the doses for most of organs-at-risk (OARs) were on average lower or equal in KBP plans compared to manual plans except for the senior planners, where the very small differences were not statistically significant. KBP data showed a systematic trend to have superior dose sparing at most parameters for the heart and ipsilateral lung. The observed decrease in the doses to these OARs could be achieved, particularly for the beginner and junior planners. Many differences were statistically significant. It is feasible to generate acceptable IMRT plans after implementing KBP for left-sided breast cancer. KBP helps to effectively improve the quality of IMRT plans against the benchmark of manual plans for less experienced planners without any manual intervention. KBP

  19. AECB strategic plan 1999

    International Nuclear Information System (INIS)

    1999-03-01

    This strategic plan provides the direction and focus required to successfully carry out our mandate in an efficient and effective manner over the next two to three years. It gives broad corporate direction by identifying where efforts need to be focussed, and therefore provides guidance for setting priorities and allocating resources. While we cannot ignore any aspect of our mandate, we must recognize that we will always have more work to do than can be accomplished within the resources available to us. Therefore we must set priorities and develop appropriate management systems to ensure that our major efforts and our resources are being directed towards those priorities. Our strategic plan is not a static document. We will always be faced with new challenges, and our strategies for meeting those challenges will also have to change. Therefore our strategic plan must be seen as a guide that reflects both the ever-changing environment and our ability to deal with new or evolving changes effectively. This plan is not intended to be a detailed operational plan. Each directorate must develop its own operational plans and procedures based on the directions in this strategic plan, and on corporate priorities and policies. (author)

  20. Animation of planning algorithms

    OpenAIRE

    Sun, Fan

    2014-01-01

    Planning is the process of creating a sequence of steps/actions that will satisfy a goal of a problem. The partial order planning (POP) algorithm is one of Artificial Intelligence approach for problem planning. By learning G52PAS module, I find that it is difficult for students to understand this planning algorithm by just reading its pseudo code and doing some exercise in writing. Students cannot know how each actual step works clearly and might miss some steps because of their confusion. ...

  1. Energy planning in Spain

    International Nuclear Information System (INIS)

    Cortina Garcia, J.

    1995-01-01

    This report aims to describe energy planning in Spain. It briefly analyses the three completed national energy plans (Plan Energetico Nacional, PEN). The fourth PEN 1991-2000 is analysed in detail, by reference to its objectives and characteristics and to developments during its first five years in operation. The Ministry of Industry and Energy has updated PEN en 1995, almost halfway through its period, and this is also summarised. Finally, there are some reflections on the future of energy planning. (Author) 46 refs

  2. Holiday Meal Planning

    Science.gov (United States)

    ... Count Glycemic Index Low-Calorie Sweeteners Sugar and Desserts Fitness Exercise & Type 1 Diabetes Get Started Safely ... plan ahead. Fitting in Sweets Learn about eating desserts on special occasions. In this section Planning Meals ...

  3. DASH Eating Plan

    Science.gov (United States)

    ... Approaches to Stop Hypertension. It is an eating plan that is based on research studies sponsored by ... risk of getting heart disease. The DASH eating plan Emphasizes vegetables, fruits, and whole-grains Includes fat- ...

  4. Planning a pregnancy

    Science.gov (United States)

    ... on Twitter Facebook Pinterest Email Print Planning a pregnancy Lupus Foundation of America September 27, 2017 Resource ... History or presence of antiphospholipid antibodies Planning Your Pregnancy Although many lupus pregnancies will have no complications, ...

  5. Automatic treatment plan re-optimization for adaptive radiotherapy guided with the initial plan DVHs

    International Nuclear Information System (INIS)

    Li, Nan; Zarepisheh, Masoud; Uribe-Sanchez, Andres; Moore, Kevin; Tian, Zhen; Zhen, Xin; Graves, Yan Jiang; Gautier, Quentin; Mell, Loren; Jia, Xun; Jiang, Steve; Zhou, Linghong

    2013-01-01

    Adaptive radiation therapy (ART) can reduce normal tissue toxicity and/or improve tumor control through treatment adaptations based on the current patient anatomy. Developing an efficient and effective re-planning algorithm is an important step toward the clinical realization of ART. For the re-planning process, manual trial-and-error approach to fine-tune planning parameters is time-consuming and is usually considered unpractical, especially for online ART. It is desirable to automate this step to yield a plan of acceptable quality with minimal interventions. In ART, prior information in the original plan is available, such as dose–volume histogram (DVH), which can be employed to facilitate the automatic re-planning process. The goal of this work is to develop an automatic re-planning algorithm to generate a plan with similar, or possibly better, DVH curves compared with the clinically delivered original plan. Specifically, our algorithm iterates the following two loops. An inner loop is the traditional fluence map optimization, in which we optimize a quadratic objective function penalizing the deviation of the dose received by each voxel from its prescribed or threshold dose with a set of fixed voxel weighting factors. In outer loop, the voxel weighting factors in the objective function are adjusted according to the deviation of the current DVH curves from those in the original plan. The process is repeated until the DVH curves are acceptable or maximum iteration step is reached. The whole algorithm is implemented on GPU for high efficiency. The feasibility of our algorithm has been demonstrated with three head-and-neck cancer IMRT cases, each having an initial planning CT scan and another treatment CT scan acquired in the middle of treatment course. Compared with the DVH curves in the original plan, the DVH curves in the resulting plan using our algorithm with 30 iterations are better for almost all structures. The re-optimization process takes about 30

  6. Hyperthermia treatment planning

    International Nuclear Information System (INIS)

    Lagendijk, J.J.W.

    2000-01-01

    The development of hyperthermia, the treatment of tumours with elevated temperatures in the range of 40-44 deg. C with treatment times over 30 min, greatly benefits from the development of hyperthermia treatment planning. This review briefly describes the state of the art in hyperthermia technology, followed by an overview of the developments in hyperthermia treatment planning. It particularly highlights the significant problems encountered with heating realistic tissue volumes and shows how treatment planning can help in designing better heating technology. Hyperthermia treatment planning will ultimately provide information about the actual temperature distributions obtained and thus the tumour control probabilities to be expected. This will improve our understanding of the present clinical results of thermoradiotherapy and thermochemotherapy, and will greatly help both in optimizing clinical heating technology and in designing optimal clinical trials. (author)

  7. External plans for radiological emergency; Plan de emergencia radiologica externo

    Energy Technology Data Exchange (ETDEWEB)

    Suarez, G; Vizuet G, J; Benitez S, J A [Instituto Nacional de Investigaciones Nucleares, A.P. 18-1027, 11801 Mexico D.F. (Mexico)

    1999-07-01

    Since 1989, the National Institute of Nuclear Research in Mexico shares in the task of Food and Water Control corresponding to the FT-86 task force of External Plans for Radiological Emergency (PERE), in charge of the Veracruz Health Services. In the PERE preparation stage previous actions are necessary developed for the preparation and updating of this plan and the task organization with the purpose to maintaining standing and operable in any time and circumstance, the capability to response in the face of an emergency. This stage englobes activities which must be realized before to carry out the Plan as they are the specialized training of personnel which participates and the execution of exercises and simulacrums. Until 1998, training and exercises for this task had been realized under diverse possible sceneries but in conditions that simulated the presence of radioactive material. For this reason, it should be emphasized the training realized during the days 6th, 7th, 8th July, 1999, in the emergency planning zone of the Plan, which to carry out using radioactive material. The National Institute of Nuclear Research had in charge of the training. This work describes all the activities for the realization of this training. (Author)

  8. Canada's green plan: Summary. Le plan vert du Canada: Resume

    Energy Technology Data Exchange (ETDEWEB)

    1990-01-01

    A summary is presented of Canada's Green Plan, a comprehensive action plan to ensure a healthy environment for the future. The plan defines targets and schedules which will drive federal environmental initiatives, and incorporates concepts of sustainable development. Elements of the plan include initiatives to combat and prevent water pollution; control ocean dumping; control smog-causing emissions; provide tighter air pollution standards; provide for sound waste management according to the principles of reduce, reuse, recycle, and recover; assess and control chemical wastes; sustain Canadian forests and maintain their diversity while shifting forest management from sustained yield to sustainable development; maintain and enhance environmental sustainability in the agro-food sector and the fishery sector; preserve and protect national parks and wildlife; and preserve and enhance the integrity, health, biodiversity and productivity of Arctic ecosystems. With respect to global-scale problems, measures will be taken to stabilize greenhouse gas emissions, limit acid rain-related emissions, and phase out the use of ozone-depleting substances. The plan also intends to improve Canada's capability to respond to environmental emergencies, improve environmental decision-making by strengthening and building of partnerships, promote environmental science research and development, and make effective and balanced use of enviromental laws, with market-based approaches for environmental protection.

  9. The Project of Planning

    DEFF Research Database (Denmark)

    Flyvbjerg, Bent

    1986-01-01

    This article contains an interview with John Friedmann. The interview covers two core areas in John Friedmann's work: (a) The history of planning, from the beginning of the industrial era till today and (b) radical planning and social mobilization. In relation to radical planning and social mobil...

  10. Generational Pension Plan Designs

    NARCIS (Netherlands)

    Huang, Xiaohong; Mahieu, Ronald

    2010-01-01

    We propose a generational plan for the occupational pension provision in which people from the same generation are pooled in a generational fund. Each fund can set its own policies independently. This plan provides the benefits of differentiation missing in the prevailing collective plan and the

  11. Language Policy and Planning.

    Science.gov (United States)

    Takala, Sauli; Sajavaara, Kari

    2000-01-01

    Focuses on foreign language planning, or the planned changes in foreign language instructional systems and in uses of languages in different social contexts with special reference to the Nordic and Baltic countries. Special attention is given to the relationship between language planning and evaluation. (Author/VWL)

  12. Hanford 200 Areas Development Plan

    Energy Technology Data Exchange (ETDEWEB)

    Rinne, C.A.; Daly, K.S.

    1993-08-01

    The purpose of the Hanford 200 Areas Development Plan (Development Plan) is to guide the physical development of the 200 Areas (which refers to the 200 East Area, 200 West Area, and 200 Area Corridor, located between the 200 East and 200 West Areas) in accordance with US Department of Energy (DOE) Order 4320.lB (DOE 1991a) by performing the following: Establishing a land-use plan and setting land-use categories that meet the needs of existing and proposed activities. Coordinating existing, 5-year, and long-range development plans and guiding growth in accordance with those plans. Establishing development guidelines to encourage cost-effective development and minimize conflicts between adjacent activities. Identifying site development issues that need further analysis. Integrating program plans with development plans to ensure a logical progression of development. Coordinate DOE plans with other agencies [(i.e., Washington State Department of Ecology (Ecology) and US Environmental Protection Agency (EPA)]. Being a support document to the Hanford Site Development Plan (DOE-RL 1990a) (parent document) and providing technical site information relative to the 200 Areas.

  13. Hanford 200 Areas Development Plan

    International Nuclear Information System (INIS)

    Rinne, C.A.; Daly, K.S.

    1993-08-01

    The purpose of the Hanford 200 Areas Development Plan (Development Plan) is to guide the physical development of the 200 Areas (which refers to the 200 East Area, 200 West Area, and 200 Area Corridor, located between the 200 East and 200 West Areas) in accordance with US Department of Energy (DOE) Order 4320.lB (DOE 1991a) by performing the following: Establishing a land-use plan and setting land-use categories that meet the needs of existing and proposed activities. Coordinating existing, 5-year, and long-range development plans and guiding growth in accordance with those plans. Establishing development guidelines to encourage cost-effective development and minimize conflicts between adjacent activities. Identifying site development issues that need further analysis. Integrating program plans with development plans to ensure a logical progression of development. Coordinate DOE plans with other agencies [(i.e., Washington State Department of Ecology (Ecology) and US Environmental Protection Agency (EPA)]. Being a support document to the Hanford Site Development Plan (DOE-RL 1990a) (parent document) and providing technical site information relative to the 200 Areas

  14. Role and importance of the spatial planning plan in the Republic of Serbia

    Directory of Open Access Journals (Sweden)

    Marinković Goran

    2017-01-01

    Full Text Available When it comes to spatial planning, it is impossible to circumvent the cadastre, which in essence is the basis for the preparation and realization of planning documents. Considering this fact in this paper, an analysis of the importance and role of the cadastre for spatial planning was carried out, whereby the obligations and procedures implemented by the cadastre in the spatial and urban planning situation in the Republic of Serbia are described in detail.

  15. Employer-sponsored pension plans

    Directory of Open Access Journals (Sweden)

    Rakonjac-Antić Tatjana N.

    2004-01-01

    Full Text Available Apart from pension plans within social insurance, in developed pension systems there are also available to individuals schemes which may to a large extent ensure a significant part of their total pension. Among them are the following: employer-sponsored pension plans or individual pension plans. The most widely used employer-sponsored pension plan in the USA is 401(k, in which both the employer and the employee contribute to the financing of the pension. These contributions as well as the return to their investment have a preferential tax treatment, i.e. do not enter a tax base. The funds are taxed only when drawn from the account in the form of a pension. This paper aims to present the functioning of 401(k pension plan as the most widely used employer sponsored pension plan in the USA, which is likely, in a modified form, to have an important place within our future reformed pension insurance system.

  16. Planning and Resource Allocation Management.

    Science.gov (United States)

    Coleman, Jack W.

    1986-01-01

    Modern scientific management techniques provide college administrators with valuable planning and resource allocation insights and enhances the decision process. The planning model should incorporate assessment, strategic planning, dynamic and long-term budgeting, operational planning, and feedback and control for actual operations. (MSE)

  17. Community participation in fire management planning: The Trinity county fire safe council's fire plan

    Science.gov (United States)

    Yvonne Everett

    2008-01-01

    In 1999, Trinity County CA, initiated a participatory fire management planning effort. Since that time, the Trinity County Fire Safe Council has completed critical portions of a fire safe plan and has begun to implement projects defined in the plan. Completion of a GIS based, landscape scale fuels reduction element in the plan defined by volunteer fire fighters, agency...

  18. Robot Plans and Human Plans: Implications for Models of Communication. Technical Report No. 314.

    Science.gov (United States)

    Bruce, Bertram

    People in interaction with others organize their perceptions of a social situation in terms of plans even when the others' plans are poorly formulated. They use their models of others' plans in formulating their own. Much of what occurs in discourse centers on a continual communication about and reformulation of one's own plans and one's own…

  19. Analysing contemporary metropolitan spatial plans in Europe through their institutional context, instrumental content and planning process

    DEFF Research Database (Denmark)

    Elinbaum, Pablo; Galland, Daniel

    2016-01-01

    This article sets out to propose and apply a qualitative framework for thinking about how to analyze and compare metropolitan spatial plans in a milieu of divergent spatial planning traditions and discretionary planning practices. In doing so, the article reviews and develops an understanding...... concerning the institutional context, instrumental content and planning processes associated with four contemporary metropolitan spatial plans in Europe, namely London, Copenhagen, Paris and Barcelona. Through the results of a multiple case study and a subsequent cross comparative analysis, the article...... stresses that contemporary metropolitan spatial plans tend to merge characteristics associated with project-based and strategy-based spatial plans, thus contrasting with the typical land-use character of municipal plans and the often strategic, growth-oriented pursuit of regional plans in Europe...

  20. business plan

    OpenAIRE

    Luzan, Dmitrij

    2009-01-01

    My thesis is dedicated to the business plan of the gastronomic facility. The thesis describes foundation of the company, analyses demand for the gastronomic services. The financial plan is being presented as well. The thesis includes the analysis of the company's environment, suppliers and customers. SWOT analysis, net present value analysis, index of the net present value and other ratio indexes are the parts of this thesis.

  1. A dosimetric comparison between traditionally planned and inverse planned radiation therapy of non-small cell lung cancer

    International Nuclear Information System (INIS)

    Wu, V.W.C.; Sham, J.S.T.; Kwong, D.L.W.

    2003-01-01

    This study applied inverse planning in 3-dimensional conformal radiation therapy (3DCRT) of non-small cell lung cancer (NSCLC) patients and evaluated its dosimetric results by comparison with the forward planning of 3DCRT and inverse planning of intensity modulated radiotherapy (IMRT). For each of the 15 NSCLC patients recruited, the forward 3DCRT, inverse 3DCRT and inverse EVIRT plans were produced using the FOCUS treatment planning system. The dosimetric results and the planner's time of all treatment plans were recorded and compared. The inverse 3DCRT plans demonstrated the best target dose homogeneity among the three planning methods. The tumour control probability of the inverse 3DCRT plans was similar to the forward plans (p 0.217) but inferior to the IMRT plans (p < 0.001). A similar pattern was observed in uncomplicated tumour control. The average planning time for the inverse 3DCRT plans was the shortest and its difference was significant compared with the forward 3DCRT plans (p < 0.001) but not with the IMRT plans (p = 0.276). In conclusion, inverse planning for 3DCRT is a reasonable alternative to the forward planning for NSCLC patients with a reduction of the planner's time. However, further dose escalation and improvement of tumour control have to rely on IMRT. Copyright (2003) Australian Institute of Radiography

  2. Planning Support Systems (PSS-Based Spatial Plan Alternatives and Environmental Assessment

    Directory of Open Access Journals (Sweden)

    Hee-Sun Choi

    2016-03-01

    Full Text Available Spatial planning is at the core of national land and urban development. Many countries and cities seek sustainable development through various means such as coordinated environmental planning, environmental assessment, and internalization of environmental analysis and planning. A Planning Support System (PSS is a GIS (Geographic Information System-based, spatial decision-making support system that incorporates a variety of theories and pertinent models. This study adopted the “What if?” model to design an alternative spatial plan that includes generation of predictive scenarios and is relatively easy to use. In the cities studied, we identified a total of six scenarios based on the main drivers of development—namely, population and spatial policies. Subsequently, we assessed the alternatives for their environmental impact, preparing sensitivity maps for each major environmental issue in the target area (natural ecosystem, air and microclimate, natural disasters. One projected advantage of the “What if?” model is that its digital visualization of proposed plans may improve public awareness and involvement. Furthermore, the tool is expected to be highly useful in ensuring the objectivity of quantitative analyses. However, it is necessary to develop a PSS that is both standardized and tailored to the particular needs of each area. Finally, the development of an e-governance system will be beneficial in ensuring public access to the decision making process.

  3. Bounded Intention Planning Revisited

    OpenAIRE

    Sievers Silvan; Wehrle Martin; Helmert Malte

    2014-01-01

    Bounded intention planning provides a pruning technique for optimal planning that has been proposed several years ago. In addition partial order reduction techniques based on stubborn sets have recently been investigated for this purpose. In this paper we revisit bounded intention planning in the view of stubborn sets.

  4. 23 CFR 710.303 - Planning.

    Science.gov (United States)

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Planning. 710.303 Section 710.303 Highways FEDERAL... ESTATE Project Development § 710.303 Planning. State and local governments conduct metropolitan and statewide planning to develop coordinated, financially constrained system plans to meet transportation needs...

  5. Energy planning and management plan

    International Nuclear Information System (INIS)

    1996-01-01

    This paper contains printed copies of 60FR 53181, October 12, 1995 and 60 FR 54151. This is a record of decision concerning the Western Area Power Administration's final draft and environmental impact statement, and Energy Planning and Management Program

  6. Federal Facilities Compliance Act, Draft Site Treatment Plan: Compliance Plan Volume. Part 2, Volume 2

    International Nuclear Information System (INIS)

    1994-01-01

    This document presents the details of the implementation of the Site Treatment Plan developed by Ames Laboratory in compliance with the Federal Facilities Compliance Act. Topics discussed in this document include: implementation of the plan; milestones; annual updates to the plan; inclusion of new waste streams; modifications of the plan; funding considerations; low-level mixed waste treatment plan and schedules; and TRU mixed waste streams

  7. National Energy Plan II

    Energy Technology Data Exchange (ETDEWEB)

    None

    1979-01-01

    This volume contains the Administration's second National Energy Plan, as required by section 801 of the Department of Energy Organization Act (Public Law 95-91). A second volume will contain an assessment of the environmental trends associated with the energy futures reported here. Detailed appendices to the Plan will be published separately. The eight chapters and their subtitles are: Crisis and Uncertainty in the World Energy Future (The Immediate Crisis and the Continuing Problem, The Emergence of the Energy Problem, The Uncertainties of the World Energy Future, World Oil Prices, Consequences for the U.S.); The U.S. Energy Future: The Implications for Policy (The Near-, Mid-, and Long-Term, The Strategy in Perspective); Conservation (Historical Changes in Energy Use, Post-Embargo Changes - In Detail, Conservation Policies and Programs, The Role of Conservation); Oil and Gas (Oil, Natural Gas); Coal and Nuclear (Coal, Nuclear, Policy for Coal and Nuclear Power); Solar and Other Inexhaustible Energy Sources (Solar Energy, Geothermal, Fusion, A Strategy for Inexhaustible Resources); Making Decisions Promptly and Fairly (Managing Future Energy Crises: Emergency Planning, Managing the Current Shortfall: The Iranian Response Plan, Managing the Long-Term Energy Problem: The Institutional Framework, Fairness in Energy Policy, Public Participation in the Development of Energy Policy); and NEP-II and the Future (The Second National Energy Plan and the Nation's Energy Future, The Second National Energy Plan and the Economy, Employment and Energy Policy, The Second National Energy Plan and Individuals, The Second National Energy Plan and Capital Markets, and The Second National Energy Plan and the Environment). (ERA citation 04:041097)

  8. Institutional Plan FY 2003 - 2007

    Energy Technology Data Exchange (ETDEWEB)

    Chartock, Michael; Hansen, Todd

    2003-01-27

    The Fiscal Year (FY) 2003-2007 Institutional Plan describes the strategic directions and key issues that Lawrence Berkeley National Laboratory management must address with the Department of Energy (DOE) in charting its future as a multiprogram national laboratory. The Plan provides an overview of the Laboratory's mission, strategic plan, initiatives, and the resources required to fulfill its role in support of national needs in fundamental science and technology, energy resources, and environmental quality. The Plan facilitates the Department of Energy's ongoing efforts to strengthen the Integrated Laboratory System. Preparation and review of the Institutional Plan is one element of the Department of Energy's strategic management planning activities, implemented through an annual planning process. The Plan supports the President's Management Agenda and the Government Performance and Results Act of 1993. The Plan complements the current performance-based contract between the Department of Energy and the Regents of the University of California, and summarizes Best Management Practices for a potential future results-based contract as a basis for achieving DOE goals and the Laboratory's scientific and operations objectives. It identifies technical and administrative directions in the context of national energy policy and research needs and the Department of Energy's program planning initiatives. Preparation of the Plan is coordinated by the Planning and Strategic Development Office from information contributed by Berkeley Lab's scientific and support divisions and DOE comments on prior years' plans. The Laboratory Mission section identifies the specific strengths of Berkeley Lab that contribute to the mission in general and the Integrated Laboratory System in particular. The Laboratory Strategic Plan section identifies the existing activities in support of DOE Office of Science and other sponsors; support for DOE goals; and the

  9. SU-E-T-357: Semi-Automated Knowledge-Based Radiation Therapy (KBRT) Planning for Head-And-Neck Cancer (HNC): Can KBRT Plans Achieve Better Results Than Manual Planning?

    International Nuclear Information System (INIS)

    Lutzky, C; Grzetic, S; Lo, J; Das, S

    2014-01-01

    Purpose: Knowledge Based Radiation Therapy Treatment (KBRT) planning can be used to semi-automatically generate IMRT plans for new patients using constraints derived from previously manually-planned, geometrically similar patients. We investigate whether KBRT plans can achieve greater dose sparing than manual plans using optimized, organspecific constraint weighting factors. Methods: KBRT planning of HNC radiotherapy cases geometrically matched each new (query) case to one of the 105 clinically approved plans in our database. The dose distribution of the planned match was morphed to fit the querys geometry. Dose-volume constraints extracted from the morphed dose distribution were used to run the IMRT optimization with no user input. In the first version, all constraints were multiplied by a weighting factor of 0.7. The weighting factors were then systematically optimized (in order of OARs with increasing separation from the target) to maximize sparing to each OAR without compromising other OARs. The optimized, second version plans were compared against the first version plans and the clinically approved plans for 45 unilateral/bilateral target cases using the dose metrics: mean, median and maximum (brainstem and cord) doses. Results: Compared to the first version, the second version significantly reduced mean/median contralateral parotid doses (>2Gy) for bilateral cases. Other changes between the two versions were not clinically meaningful. Compared to the original clinical plans, both bilateral and unilateral plans in the second version had lower average dose metrics for 5 of the 6 OARs. Compared to the original plans, the second version achieved dose sparing that was at least as good for all OARs and better for the ipsilateral parotid (bilateral) and oral cavity (bilateral/unilateral). Differences in planning target volume coverage metrics were not clinically significant. Conclusion: HNC-KBRT planning generated IMRT plans with at least equivalent dose sparing to

  10. SU-E-T-357: Semi-Automated Knowledge-Based Radiation Therapy (KBRT) Planning for Head-And-Neck Cancer (HNC): Can KBRT Plans Achieve Better Results Than Manual Planning?

    Energy Technology Data Exchange (ETDEWEB)

    Lutzky, C; Grzetic, S; Lo, J; Das, S [Duke University Medical Center, Durham, NC (United States)

    2014-06-01

    Purpose: Knowledge Based Radiation Therapy Treatment (KBRT) planning can be used to semi-automatically generate IMRT plans for new patients using constraints derived from previously manually-planned, geometrically similar patients. We investigate whether KBRT plans can achieve greater dose sparing than manual plans using optimized, organspecific constraint weighting factors. Methods: KBRT planning of HNC radiotherapy cases geometrically matched each new (query) case to one of the 105 clinically approved plans in our database. The dose distribution of the planned match was morphed to fit the querys geometry. Dose-volume constraints extracted from the morphed dose distribution were used to run the IMRT optimization with no user input. In the first version, all constraints were multiplied by a weighting factor of 0.7. The weighting factors were then systematically optimized (in order of OARs with increasing separation from the target) to maximize sparing to each OAR without compromising other OARs. The optimized, second version plans were compared against the first version plans and the clinically approved plans for 45 unilateral/bilateral target cases using the dose metrics: mean, median and maximum (brainstem and cord) doses. Results: Compared to the first version, the second version significantly reduced mean/median contralateral parotid doses (>2Gy) for bilateral cases. Other changes between the two versions were not clinically meaningful. Compared to the original clinical plans, both bilateral and unilateral plans in the second version had lower average dose metrics for 5 of the 6 OARs. Compared to the original plans, the second version achieved dose sparing that was at least as good for all OARs and better for the ipsilateral parotid (bilateral) and oral cavity (bilateral/unilateral). Differences in planning target volume coverage metrics were not clinically significant. Conclusion: HNC-KBRT planning generated IMRT plans with at least equivalent dose sparing to

  11. Planning for Pregnancy

    Science.gov (United States)

    ... Before Pregnancy Home Overview Planning for Pregnancy Women Men Image Library Women Who Want to Become Pregnant Women Who Do Not Want to Become Pregnant Hugging Nutrition Physical Activity Visiting the Doctor Planning for Pregnancy Language: English ( ...

  12. Planning of nets

    International Nuclear Information System (INIS)

    Carberry, M

    1996-01-01

    The paper is about the planning of nets in areas of low density like it is the case of the rural areas. The author includes economic and technological aspects, planning of nets, demands and management among others

  13. Breastfeeding: Planning Ahead

    Medline Plus

    Full Text Available ... To receive Breastfeeding email updates Enter email Submit Planning ahead From choosing the crib to finding a ... care Get health insurance Get help with family planning Get help with mental health Find girls' health ...

  14. Breastfeeding: Planning Ahead

    Medline Plus

    Full Text Available ... and jobs View all pages in this section Home It's Only Natural Planning ahead It's Only Natural Planning ahead Breastfeeding and baby basics Making breastfeeding work for you Addressing breastfeeding myths Overcoming challenges Finding ...

  15. Preparing strategic information management plans for hospitals: a practical guideline SIM plans for hospitals: a guideline.

    Science.gov (United States)

    Brigl, B; Ammenwerth, E; Dujat, C; Gräber, S; Grosse, A; Häber, A; Jostes, C; Winter, A

    2005-01-01

    Systematic information management in hospitals demands for a strategic information management plan (SIM plan). As preparing a SIM plan is a considerable challenge we provide a practical guideline that is directly applicable when a SIM plan is going to be prepared. The guideline recommends a detailed structure of a SIM plan and gives advice about its content and the preparation process. It may be used as template, which can be adapted to the individual demands of any hospital. The guideline was used in several hospitals preparing a SIM plan. Experiences showed that the SIM plans could be prepared very efficiently and timely using the guideline, that the proposed SIM plan structure suited well, that the guideline offers enough flexibility to meet the requirements of the individual hospitals and that the specific recommendations of the guideline were very helpful. Nevertheless, we must strive for a more comprehensive theory of strategic information management planning which -- in the sense of enterprise architecture planning -- represents the intrinsic correlations of the different parts of a SIM plan to a greater extent.

  16. ANSTO strategic plan 1988-1993

    International Nuclear Information System (INIS)

    1988-12-01

    This Strategic Plan outlines the development of the Australian Nuclear Science and Technology Organisation in the five year period 1988/89-1992/93. Its formulation is a continuation of the corporate planning process, initiated after the promulgation of the ANSTO Act in April 1987, which culminated in the publication of the ANSTO Corporate Plan, 1987. The Plan constitutes the basis for the development of business plans for each sector of the Organisation

  17. Develop a Professional Learning Plan

    Science.gov (United States)

    Journal of Staff Development, 2013

    2013-01-01

    A professional learning plan establishes short-and long-term plans for professional learning and implementation of the learning. Such plans guide individuals, schools, districts, and states in coordinating learning experiences designed to achieve outcomes for educators and students. Professional learning plans focus on the program of educator…

  18. 44 CFR 10.7 - Planning.

    Science.gov (United States)

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Planning. 10.7 Section 10.7... GENERAL ENVIRONMENTAL CONSIDERATIONS Agency Implementing Procedures § 10.7 Planning. (a) Early planning. The Regional Administrator shall integrate the NEPA process with other planning at the earliest...

  19. Retirement Planning the Easy Way.

    Science.gov (United States)

    Fields, Cheryl D.

    1996-01-01

    Options available to college faculty for planning their retirement benefits are described, including defined benefit plans, defined contribution plans, and methods for customizing a pension plan. Data for 1993 on American households owning interest-earning assets (passbook savings, money market deposit accounts, certificates of deposit, checking…

  20. Plan Merging : Experimental results

    NARCIS (Netherlands)

    De Weerdt, M.M.; Van der Krogt, R.P.J.; Zutt, J.

    2003-01-01

    In this paper we discuss the results of a plan merging algorithm. This algorithm coordinates the plans of multiple, autonomous agents, each able to independently find a plan. This algorithm is evaluated using realistic data from a taxi company. We show that when we allow passengers to be a few

  1. The transportation institutional plan: Cooperative planning for NWPA transportation

    International Nuclear Information System (INIS)

    Denny, S.H.; Livingston-Behan, E.A.

    1987-01-01

    The Transportation Institutional Plan, published in 1986 by the U.S. Department of Energy's Office of Civilian Radioactive Waste Management (OCRWM), defines a process for effective interaction among those who may be affected by transportation activities conducted under provisions of the Nuclear Waste Policy Act of 1982 (NWPA). The Plan describes formal mechanisms for identifying, addressing, and resolving specific transportation issues. An appendix to the Plan includes detailed discussion of the following transportation issues: (1) the transportation of defense waste; (2) prenotification; (3) physical and rail shipments; (4) highway routing; (5) rail routing; (6) inspection and enforcement for highway and rail shipments; (7) emergency response; (8) liability coverage for transportation to NWPA facilities; (9) cask design and testing; (10) overweight truck shipments; (11) rail service analysis; (12) mixture of transportation modes; (13) transportation infrastructure improvements; (14) OCRWM training standards; (15) transportation operational procedures; and (16) State, Tribal, and local regulation of transportation. The OCRWM's intent is to provide an open accounting of planning, to identify opportunities for public involvement in program activities, and to foster communication and negotiation in the cooperative development of a safe, efficient, and cost-effective NWPA transportation program

  2. The Waypoint Planning Tool: Real Time Flight Planning for Airborne Science

    Science.gov (United States)

    He, M.; Goodman, H. M.; Blakeslee, R.; Hall, J. M.

    2010-12-01

    NASA Earth science research utilizes both spaceborne and airborne real time observations in the planning and operations of its field campaigns. The coordination of air and space components is critical to achieve the goals and objectives and ensure the success of an experiment. Spaceborne imagery provides regular and continual coverage of the Earth and it is a significant component in all NASA field experiments. Real time visible and infrared geostationary images from GOES satellites and multi-spectral data from the many elements of the NASA suite of instruments aboard the TRMM, Terra, Aqua, Aura, and other NASA satellites have become norm. Similarly, the NASA Airborne Science Program draws upon a rich pool of instrumented aircraft. The NASA McDonnell Douglas DC-8, Lockheed P3 Orion, DeHavilland Twin Otter, King Air B200, Gulfstream-III are all staples of a NASA’s well-stocked, versatile hangar. A key component in many field campaigns is coordinating the aircraft with satellite overpasses, other airplanes and the constantly evolving, dynamic weather conditions. Given the variables involved, developing a good flight plan that meets the objectives of the field experiment can be a challenging and time consuming task. Planning a research aircraft mission within the context of meeting the science objectives is complex task because it is much more than flying from point A to B. Flight plans typically consist of flying a series of transects or involve dynamic path changes when “chasing” a hurricane or forest fire. These aircraft flight plans are typically designed by the mission scientists then verified and implemented by the navigator or pilot. Flight planning can be an arduous task requiring frequent sanity checks by the flight crew. This requires real time situational awareness of the weather conditions that affect the aircraft track. Scientists at the University of Alabama-Huntsville and the NASA Marshall Space Flight Center developed the Waypoint Planning Tool

  3. Technology Implementation Plan

    DEFF Research Database (Denmark)

    Jensen, Karsten Ingerslev; Schultz, Jørgen Munthe

    The Technology Implementation Plan (TIP) describes the main project results and the intended future use. The TIP is confidential.......The Technology Implementation Plan (TIP) describes the main project results and the intended future use. The TIP is confidential....

  4. Oncentra brachytherapy planning system.

    Science.gov (United States)

    Yang, Jack

    2018-03-27

    In modern cancer management, treatment planning has progressed as a contemporary tool with all the advances in computing power in recent years. One of the advanced planning tools uses 3-dimensional (3D) data sets for accurate dose distributions in patient prescription. Among these planning processes, brachytherapy has been a very important part of a successful cancer management program, offering clinical benefits with specific or combined treatments with external beam therapy. In this chapter, we mainly discussed the Elekta Oncentra planning system, which is the main treatment planning tool for high-dose rate (HDR) modality in our facility and in many other facilities in the United States. HDR is a technically advanced form of brachytherapy; a high-intensity radiation source (3.6 mm in length) is delivered with step motor in submillimeter precision under computer guidance directly into the tumor areas while minimizing injury to surrounding normal healthy tissue. Oncentra planning is the key component to generate a deliverable brachytherapy procedure, which is executed on the microSelectron V3 remote afterloader treatment system. Creating a highly conformal plan can be a time-consuming task. The development of Oncentra software (version 4.5.3) offers a variety of useful tools that facilitate many of the clinical challenging tasks for planning, such as contouring and image reconstruction, as well as rapid planning calculations with dose and dose volume histogram analysis. Oncentra Brachy module creates workflow and optimizes the planning accuracy for wide varieties of clinical HDR treatments, such as skin, gynecologic (GYN), breast, prostate, and many other applications. The treatment file can also be transferred to the afterloader control station for speedy delivery. The design concept, calculation algorithms, and optimization modules presented some key characteristics to plan and treat the patients effectively and accurately. The dose distribution and accuracy of

  5. Environmental Implementation Plan

    International Nuclear Information System (INIS)

    1994-02-01

    The Environmental Implementation Plan (EIP) is a dynamic long-range environmental-protection plan for SRS. The EIP communicates the current and future (five year) environmental plans from individual organizations and divisions as well as site environmental initiatives which are designed to protect the environment and meet or exceed compliance with changing environmental/ regulatory requirements. Communication with all site organizations is essential for making the site environmental planning process work. Demonstrating environmental excellence is a high priority embodied in DOE and WSRC policy. Because of your support and participation in the three EIP initiatives; Reflections, Sectional Revision, and Integrated Planning, improvements are being made to the EIP and SRS environmental protection programs. I appreciate the ''Partnership in Environmental Excellence'' formed by the environmental coordinators and professionals who work daily toward our goal of compliance and environmental excellence. I look forward to seeing continued success and improvement in our environmental protection programs through combined efforts of all site organizations to protect our employees, the public health, and the environment. Together, we will achieve our site vision for SRS to be the recognized model for Environmental Excellence in the DOE Nuclear Weapons Complex

  6. Environmental Implementation Plan

    Energy Technology Data Exchange (ETDEWEB)

    1994-02-01

    The Environmental Implementation Plan (EIP) is a dynamic long-range environmental-protection plan for SRS. The EIP communicates the current and future (five year) environmental plans from individual organizations and divisions as well as site environmental initiatives which are designed to protect the environment and meet or exceed compliance with changing environmental/ regulatory requirements. Communication with all site organizations is essential for making the site environmental planning process work. Demonstrating environmental excellence is a high priority embodied in DOE and WSRC policy. Because of your support and participation in the three EIP initiatives; Reflections, Sectional Revision, and Integrated Planning, improvements are being made to the EIP and SRS environmental protection programs. I appreciate the ``Partnership in Environmental Excellence`` formed by the environmental coordinators and professionals who work daily toward our goal of compliance and environmental excellence. I look forward to seeing continued success and improvement in our environmental protection programs through combined efforts of all site organizations to protect our employees, the public health, and the environment. Together, we will achieve our site vision for SRS to be the recognized model for Environmental Excellence in the DOE Nuclear Weapons Complex.

  7. Evaluating the role of collaborative planning in BC's Parks and Protected Areas Management Planning process

    OpenAIRE

    Ronmark, Tracy

    2005-01-01

    BC's protected areas system has recently doubled in size as a result of land use planning across the province. Managing protected areas to meet many goals requires thoughtful planning that involves stakeholder participation and dispute resolution through the plan development and implementation stages. This research identifies the best practices for planning and evaluates protected areas management planning processes based on those criteria. Evaluative criteria were developed from a literature...

  8. Strategic planning for neuroradiologists.

    Science.gov (United States)

    Berlin, Jonathan W; Lexa, Frank J

    2012-08-01

    Strategic planning is becoming essential to neuroradiology as the health care environment continues to emphasize cost efficiency, teamwork and collaboration. A strategic plan begins with a mission statement and vision of where the neuroradiology division would like to be in the near future. Formalized strategic planning frameworks, such as the strengths, weaknesses, opportunities and threats (SWOT), and the Balanced Scorecard frameworks, can help neuroradiology divisions determine their current position in the marketplace. Communication, delegation, and accountability in neuroradiology is essential in executing an effective strategic plan. Copyright © 2012 Elsevier Inc. All rights reserved.

  9. Business Plans For Dummies

    CERN Document Server

    Tiffany, Paul; Barrow, Colin

    2011-01-01

    A full updated and extended second edition of an established UK bestseller Business Plans For Dummies 2nd Edition features new and updated information on formulating a solid business plan to build a secure business - even in an economic downturn. Complete with a brand new business plan template to get you started this expert guide offers fresh advice on reading the competitive marketplace and assessing your business in the current economic climate. It walks you step-by-step through every aspect of planning achievable business goals and diversification strategies, identifying trends, exploring

  10. Planning Complex Projects Automatically

    Science.gov (United States)

    Henke, Andrea L.; Stottler, Richard H.; Maher, Timothy P.

    1995-01-01

    Automated Manifest Planner (AMP) computer program applies combination of artificial-intelligence techniques to assist both expert and novice planners, reducing planning time by orders of magnitude. Gives planners flexibility to modify plans and constraints easily, without need for programming expertise. Developed specifically for planning space shuttle missions 5 to 10 years ahead, with modifications, applicable in general to planning other complex projects requiring scheduling of activities depending on other activities and/or timely allocation of resources. Adaptable to variety of complex scheduling problems in manufacturing, transportation, business, architecture, and construction.

  11. Inverse planning IMRT

    International Nuclear Information System (INIS)

    Rosenwald, J.-C.

    2008-01-01

    The lecture addressed the following topics: Optimizing radiotherapy dose distribution; IMRT contributes to optimization of energy deposition; Inverse vs direct planning; Main steps of IMRT; Background of inverse planning; General principle of inverse planning; The 3 main components of IMRT inverse planning; The simplest cost function (deviation from prescribed dose); The driving variable : the beamlet intensity; Minimizing a 'cost function' (or 'objective function') - the walker (or skier) analogy; Application to IMRT optimization (the gradient method); The gradient method - discussion; The simulated annealing method; The optimization criteria - discussion; Hard and soft constraints; Dose volume constraints; Typical user interface for definition of optimization criteria; Biological constraints (Equivalent Uniform Dose); The result of the optimization process; Semi-automatic solutions for IMRT; Generalisation of the optimization problem; Driving and driven variables used in RT optimization; Towards multi-criteria optimization; and Conclusions for the optimization phase. (P.A.)

  12. The two faces of plan repair

    NARCIS (Netherlands)

    Van der Krogt, R.P.J.; De Weerdt, M.M.

    2004-01-01

    Plan repair has two faces. Alternately, a plan repair method looks like a planning method, or looks like a method that does exactly the opposite, i.e., removing actions from a plan. We propose a general framework for plan repair that shows the relation between these two alternating steps. Any plan

  13. Diagnosis of plan structure Violations

    NARCIS (Netherlands)

    Roos, Nico

    2007-01-01

    Failures in plan execution can be attributed to errors in the execution of plan steps or violations of the plan structure. The structure of a plan prescribes which actions have to be performed and which precedence constraints between them have to be respected. Especially in multi-agent environments

  14. When daily planning improves employee performance: The importance of planning type, engagement, and interruptions.

    Science.gov (United States)

    Parke, Michael R; Weinhardt, Justin M; Brodsky, Andrew; Tangirala, Subrahmaniam; DeVoe, Sanford E

    2018-03-01

    Does planning for a particular workday help employees perform better than on other days they fail to plan? We investigate this question by identifying 2 distinct types of daily work planning to explain why and when planning improves employees' daily performance. The first type is time management planning (TMP)-creating task lists, prioritizing tasks, and determining how and when to perform them. We propose that TMP enhances employees' performance by increasing their work engagement, but that these positive effects are weakened when employees face many interruptions in their day. The second type is contingent planning (CP) in which employees anticipate possible interruptions in their work and plan for them. We propose that CP helps employees stay engaged and perform well despite frequent interruptions. We investigate these hypotheses using a 2-week experience-sampling study. Our findings indicate that TMP's positive effects are conditioned upon the amount of interruptions, but CP has positive effects that are not influenced by the level of interruptions. Through this study, we help inform workers of the different planning methods they can use to increase their daily motivation and performance in dynamic work environments. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  15. Education plan

    International Nuclear Information System (INIS)

    Baur, J.

    1987-01-01

    There is pressing need for education of fusion people and those in the radiation effects community on the role of radiation hardening in radiation diagnostic. There is no plan at present to do this. The plan is to be proposed and developed. The education methods should include distribution of a primer, the proceedings of this workshop, and updated data compilations and talks by experts at the fusion labs, universities, and meetings

  16. Supply chain planning classification

    Science.gov (United States)

    Hvolby, Hans-Henrik; Trienekens, Jacques; Bonde, Hans

    2001-10-01

    Industry experience a need to shift in focus from internal production planning towards planning in the supply network. In this respect customer oriented thinking becomes almost a common good amongst companies in the supply network. An increase in the use of information technology is needed to enable companies to better tune their production planning with customers and suppliers. Information technology opportunities and supply chain planning systems facilitate companies to monitor and control their supplier network. In spite if these developments, most links in today's supply chains make individual plans, because the real demand information is not available throughout the chain. The current systems and processes of the supply chains are not designed to meet the requirements now placed upon them. For long term relationships with suppliers and customers, an integrated decision-making process is needed in order to obtain a satisfactory result for all parties. Especially when customized production and short lead-time is in focus. An effective value chain makes inventory available and visible among the value chain members, minimizes response time and optimizes total inventory value held throughout the chain. In this paper a supply chain planning classification grid is presented based current manufacturing classifications and supply chain planning initiatives.

  17. Breastfeeding: Planning Ahead

    Medline Plus

    Full Text Available ... health care Get health insurance Get help with family planning Get help with mental health Find girls' health ... health care Get health insurance Get help with family planning Get help with mental health Find girls' health ...

  18. Breastfeeding: Planning Ahead

    Medline Plus

    Full Text Available ... health topics Find Help Get breastfeeding help Get health care Get health insurance Get help with family planning ... health topics Find Help Get breastfeeding help Get health care Get health insurance Get help with family planning ...

  19. Breastfeeding: Planning Ahead

    Medline Plus

    Full Text Available ... Help Get breastfeeding help Get health care Get health insurance Get help with family planning Get help with ... Help Get breastfeeding help Get health care Get health insurance Get help with family planning Get help with ...

  20. ECP divisional training: plan 1996

    OpenAIRE

    Storr, Kenneth Mick

    1996-01-01

    The divisional training plan is produced each year at the request of the Joint Training Board (JTB) following a recommendation in the 1991 CERN Training Plan which states that divisions should produce a plan setting out training priorities. This plan presents a review of training activities. a report on ECP progress in implementing the recommendations of the 1995 CERN training plan, a discussion of divisional training objectives, and a summary of training requests generated by the 1996 period...